Engineering Paper-Based Sensors for Zika Virus

Meagher, Robert J.; Negrete, Oscar A.; Van Rompay, Koen K.

doi:10.1016/j.molmed.2016.05.009

Title: Engineering Paper-Based Sensors for Zika Virus

Abstract

The emergence of Zika virus in Latin America has created an urgent need for new, simple yet sensitive diagnostic tests. We highlight recent work using paper-based sensors coupled with CRISPR/Cas9 to detect Zika RNA, as a new approach to rapid development and deployment of field-ready diagnostics for emerging infectious diseases.

Authors:

Meagher, Robert J. ^[1]; Negrete, Oscar A. ^[1]; Van Rompay, Koen K. ^[2]

Sandia National Lab. (SNL-CA), Livermore, CA (United States)
Univ. of California, Davis, CA (United States). California Natiional Primate Research Center

Publication Date:: Mon May 30 00:00:00 EDT 2016

Research Org.:: Sandia National Lab. (SNL-CA), Livermore, CA (United States)

Sponsoring Org.:: USDOE National Nuclear Security Administration (NNSA)

OSTI Identifier:: 1259488

Alternate Identifier(s):: OSTI ID: 1435397

Report Number(s):: SAND-2016-4594J
Journal ID: ISSN 1471-4914; 640221

Grant/Contract Number:: AC04-94AL85000

Resource Type:: Accepted Manuscript

Journal Name:: Trends in Molecular Medicine

Additional Journal Information:: Journal Volume: 22; Journal Issue: 7; Journal ID: ISSN 1471-4914

Publisher:: Elsevier

Country of Publication:: United States

Language:: English

Subject:: 60 APPLIED LIFE SCIENCES

Citation Formats


                    Meagher, Robert J., Negrete, Oscar A., and Van Rompay, Koen K. Engineering Paper-Based Sensors for Zika Virus.  United States: N. p., 2016. 
Web.  doi:10.1016/j.molmed.2016.05.009.

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                    Meagher, Robert J., Negrete, Oscar A., & Van Rompay, Koen K. Engineering Paper-Based Sensors for Zika Virus.  United States.  https://doi.org/10.1016/j.molmed.2016.05.009

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                    Meagher, Robert J., Negrete, Oscar A., and Van Rompay, Koen K. Mon .  
"Engineering Paper-Based Sensors for Zika Virus".  United States.  https://doi.org/10.1016/j.molmed.2016.05.009.  https://www.osti.gov/servlets/purl/1259488.

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@article{osti_1259488,

  title        = {Engineering Paper-Based Sensors for Zika Virus},

  author       = {Meagher, Robert J. and Negrete, Oscar A. and Van Rompay, Koen K.},

  abstractNote = {The emergence of Zika virus in Latin America has created an urgent need for new, simple yet sensitive diagnostic tests. We highlight recent work using paper-based sensors coupled with CRISPR/Cas9 to detect Zika RNA, as a new approach to rapid development and deployment of field-ready diagnostics for emerging infectious diseases.},

  doi          = {10.1016/j.molmed.2016.05.009},

  journal      = {Trends in Molecular Medicine},

  number       = 7,

  volume       = 22,

  place        = {United States},

  year         = {Mon May 30 00:00:00 EDT 2016},

  month        = {Mon May 30 00:00:00 EDT 2016}

}

Copy to clipboard

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https://doi.org/10.1016/j.molmed.2016.05.009

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Title: Engineering Paper-Based Sensors for Zika Virus

Abstract

Citation Formats

What Ebola tells us about outbreak diagnostic readiness journal, May 2015

Paper-Based Synthetic Gene Networks journal, November 2014

Nucleic acid sequence-based amplification journal, March 1991

NASBATM isothermal enzymatic in vitro nucleic acid amplification optimized for the diagnosis of HIV-1 infection journal, December 1991

Isothermal nucleic acid amplification technologies for point-of-care diagnostics: a critical review journal, January 2012

Quenching of Unincorporated Amplification Signal Reporters in Reverse-Transcription Loop-Mediated Isothermal Amplification Enabling Bright, Single-Step, Closed-Tube, and Multiplexed Detection of RNA Viruses journal, March 2016

Development and deployment of a rapid recombinase polymerase amplification Ebola virus detection assay in Guinea in 2015 journal, November 2015

Zika Virus journal, March 2016

The applications of CRISPR/Cas system in molecular detection journal, October 2018

Detection of chikungunya virus‐specific IgM on laser‐cut paper‐based device using pseudo‐particles as capture antigen journal, February 2019

Field-Effect Biosensors for On-Site Detection: Recent Advances and Promising Targets journal, September 2017

Validation of use of the miniPCR thermocycler for Ebola and Zika virus detection journal, May 2019

Simpler, Faster, and Sensitive Zika Virus Assay Using Smartphone Detection of Loop-mediated Isothermal Amplification on Paper Microfluidic Chips journal, August 2018

Loop-Mediated Isothermal Amplification (LAMP) for the Diagnosis of Zika Virus: A Review journal, December 2019

A sensitive electrochemical immunosensor for label-free detection of Zika-virus protein journal, June 2018

Synthetic Biology Enables Programmable Cell‐Based Biosensors journal, January 2020

Computing with biological switches and clocks journal, June 2018

In vitro multi-enzymatic cascades using recombinant lysates of E. coli: an emerging biocatalysis platform journal, January 2020

Precise and Programmable Detection of Mutations Using Ultraspecific Riboregulators journal, October 2020

Cell-free microcompartmentalised transcription–translation for the prototyping of synthetic communication networks journal, August 2019

Cell-free synthetic biology for in vitro biosynthesis of pharmaceutical natural products journal, June 2018

Synergistic and non-specific nucleic acid production by T7 RNA polymerase and Bsu DNA polymerase catalyzed by single-stranded polynucleotides journal, June 2018

Blossom of CRISPR technologies and applications in disease treatment journal, December 2018

Methods to reduce variability in E. Coli-based cell-free protein expression experiments journal, December 2019

Long-Term Stability Monitoring of Printed Proteins on Paper-Based Membranes journal, August 2019

Complex cellular logic computation using ribocomputing devices journal, July 2017

Orthogonal regulation of DNA nanostructure self-assembly and disassembly using antibodies journal, December 2019

A sensitive electrochemical immunosensor for label-free detection of Zika-virus protein journal, June 2018

Simpler, Faster, and Sensitive Zika Virus Assay Using Smartphone Detection of Loop-mediated Isothermal Amplification on Paper Microfluidic Chips journal, August 2018

Rapid, Affordable and Portable Medium-Throughput Molecular Device for Zika Virus journal, December 2016

Rapid acquisition and model-based analysis of cell-free transcription–translation reactions from nonmodel bacteria journal, April 2018

Achieving large dynamic range control of gene expression with a compact RNA transcription–translation regulator journal, April 2017

Addressable configurations of DNA nanostructures for rewritable memory journal, August 2017

High-density functional-RNA arrays as a versatile platform for studying RNA-based interactions journal, May 2018

Strategies for in vitro engineering of the translation machinery journal, November 2019

Low-cost detection of norovirus using paper-based cell-free systems and synbody-based viral enrichment journal, January 2018

Microbially derived biosensors for diagnosis, monitoring and epidemiology journal, August 2017

A modular yeast biosensor for low-cost point-of-care pathogen detection journal, June 2017

BioBits™ Explorer: A modular synthetic biology education kit journal, August 2018

BioBits™ Bright: A fluorescent synthetic biology education kit journal, August 2018

Point-of-care biomarker quantification enabled by sample-specific calibration journal, September 2019

Rapid colorimetric detection of Zika virus from serum and urine specimens by reverse transcription loop-mediated isothermal amplification (RT-LAMP) journal, September 2017

Validation of use of the miniPCR thermocycler for Ebola and Zika virus detection journal, May 2019

Computer‐aided biochemical programming of synthetic microreactors as diagnostic devices journal, June 2018

New Paradigms for Virus Detection, Surveillance and Control of Zika Virus Vectors in the Settings of Southeast Asia journal, September 2016

An Alternative Medical Diagnosis Method: Biosensors for Virus Detection journal, May 2019

Loop-Mediated Isothermal Amplification (LAMP) for the Diagnosis of Zika Virus: A Review journal, December 2019

A Paper-Based Device for Performing Loop-Mediated Isothermal Amplification with Real-Time Simultaneous Detection of Multiple DNA Targets journal, January 2017

Development of a novel peptide aptamer-based immunoassay to detect Zika virus in serum and urine journal, January 2018

What Ebola tells us about outbreak diagnostic readiness
journal, May 2015

Paper-Based Synthetic Gene Networks
journal, November 2014

Nucleic acid sequence-based amplification
journal, March 1991

NASBA^TM isothermal enzymatic in vitro nucleic acid amplification optimized for the diagnosis of HIV-1 infection
journal, December 1991

Isothermal nucleic acid amplification technologies for point-of-care diagnostics: a critical review
journal, January 2012

Quenching of Unincorporated Amplification Signal Reporters in Reverse-Transcription Loop-Mediated Isothermal Amplification Enabling Bright, Single-Step, Closed-Tube, and Multiplexed Detection of RNA Viruses
journal, March 2016

Development and deployment of a rapid recombinase polymerase amplification Ebola virus detection assay in Guinea in 2015
journal, November 2015

Zika Virus
journal, March 2016

The applications of CRISPR/Cas system in molecular detection
journal, October 2018

Detection of chikungunya virus‐specific IgM on laser‐cut paper‐based device using pseudo‐particles as capture antigen
journal, February 2019

Field-Effect Biosensors for On-Site Detection: Recent Advances and Promising Targets
journal, September 2017

Validation of use of the miniPCR thermocycler for Ebola and Zika virus detection
journal, May 2019

Simpler, Faster, and Sensitive Zika Virus Assay Using Smartphone Detection of Loop-mediated Isothermal Amplification on Paper Microfluidic Chips
journal, August 2018

Loop-Mediated Isothermal Amplification (LAMP) for the Diagnosis of Zika Virus: A Review
journal, December 2019

A sensitive electrochemical immunosensor for label-free detection of Zika-virus protein
journal, June 2018

Synthetic Biology Enables Programmable Cell‐Based Biosensors
journal, January 2020

Computing with biological switches and clocks
journal, June 2018

In vitro multi-enzymatic cascades using recombinant lysates of E. coli: an emerging biocatalysis platform
journal, January 2020

Precise and Programmable Detection of Mutations Using Ultraspecific Riboregulators
journal, October 2020

Cell-free microcompartmentalised transcription–translation for the prototyping of synthetic communication networks
journal, August 2019

Cell-free synthetic biology for in vitro biosynthesis of pharmaceutical natural products
journal, June 2018

Synergistic and non-specific nucleic acid production by T7 RNA polymerase and Bsu DNA polymerase catalyzed by single-stranded polynucleotides
journal, June 2018

Blossom of CRISPR technologies and applications in disease treatment
journal, December 2018

Methods to reduce variability in E. Coli-based cell-free protein expression experiments
journal, December 2019

Long-Term Stability Monitoring of Printed Proteins on Paper-Based Membranes
journal, August 2019

Complex cellular logic computation using ribocomputing devices
journal, July 2017

Orthogonal regulation of DNA nanostructure self-assembly and disassembly using antibodies
journal, December 2019

A sensitive electrochemical immunosensor for label-free detection of Zika-virus protein
journal, June 2018

Simpler, Faster, and Sensitive Zika Virus Assay Using Smartphone Detection of Loop-mediated Isothermal Amplification on Paper Microfluidic Chips
journal, August 2018

Rapid, Affordable and Portable Medium-Throughput Molecular Device for Zika Virus
journal, December 2016

Rapid acquisition and model-based analysis of cell-free transcription–translation reactions from nonmodel bacteria
journal, April 2018

Achieving large dynamic range control of gene expression with a compact RNA transcription–translation regulator
journal, April 2017

Addressable configurations of DNA nanostructures for rewritable memory
journal, August 2017

High-density functional-RNA arrays as a versatile platform for studying RNA-based interactions
journal, May 2018

Strategies for in vitro engineering of the translation machinery
journal, November 2019

Low-cost detection of norovirus using paper-based cell-free systems and synbody-based viral enrichment
journal, January 2018

Microbially derived biosensors for diagnosis, monitoring and epidemiology
journal, August 2017

A modular yeast biosensor for low-cost point-of-care pathogen detection
journal, June 2017

BioBits™ Explorer: A modular synthetic biology education kit
journal, August 2018

BioBits™ Bright: A fluorescent synthetic biology education kit
journal, August 2018

Point-of-care biomarker quantification enabled by sample-specific calibration
journal, September 2019

Rapid colorimetric detection of Zika virus from serum and urine specimens by reverse transcription loop-mediated isothermal amplification (RT-LAMP)
journal, September 2017

Validation of use of the miniPCR thermocycler for Ebola and Zika virus detection
journal, May 2019

Computer‐aided biochemical programming of synthetic microreactors as diagnostic devices
journal, June 2018

New Paradigms for Virus Detection, Surveillance and Control of Zika Virus Vectors in the Settings of Southeast Asia
journal, September 2016

An Alternative Medical Diagnosis Method: Biosensors for Virus Detection
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Loop-Mediated Isothermal Amplification (LAMP) for the Diagnosis of Zika Virus: A Review
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A Paper-Based Device for Performing Loop-Mediated Isothermal Amplification with Real-Time Simultaneous Detection of Multiple DNA Targets
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Development of a novel peptide aptamer-based immunoassay to detect Zika virus in serum and urine
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