Analytical tools to assess aging in humans: The rise of geri-omics
- Authors:
- Publication Date:
- Sponsoring Org.:
- USDOE Office of Nuclear Energy (NE), Nuclear Fuel Cycle and Supply Chain
- OSTI Identifier:
- 1244563
- Grant/Contract Number:
- UID/AMB/50017/2013
- Resource Type:
- Publisher's Accepted Manuscript
- Journal Name:
- TrAC, Trends in Analytical Chemistry (Personal Edition)
- Additional Journal Information:
- Journal Name: TrAC, Trends in Analytical Chemistry (Personal Edition) Journal Volume: 80 Journal Issue: C; Journal ID: ISSN 0165-9936
- Publisher:
- Elsevier
- Country of Publication:
- Netherlands
- Language:
- English
Citation Formats
da Costa, João Pinto, Rocha-Santos, Teresa, and Duarte, Armando C. Analytical tools to assess aging in humans: The rise of geri-omics. Netherlands: N. p., 2016.
Web. doi:10.1016/j.trac.2015.09.011.
da Costa, João Pinto, Rocha-Santos, Teresa, & Duarte, Armando C. Analytical tools to assess aging in humans: The rise of geri-omics. Netherlands. https://doi.org/10.1016/j.trac.2015.09.011
da Costa, João Pinto, Rocha-Santos, Teresa, and Duarte, Armando C. Wed .
"Analytical tools to assess aging in humans: The rise of geri-omics". Netherlands. https://doi.org/10.1016/j.trac.2015.09.011.
@article{osti_1244563,
title = {Analytical tools to assess aging in humans: The rise of geri-omics},
author = {da Costa, João Pinto and Rocha-Santos, Teresa and Duarte, Armando C.},
abstractNote = {},
doi = {10.1016/j.trac.2015.09.011},
journal = {TrAC, Trends in Analytical Chemistry (Personal Edition)},
number = C,
volume = 80,
place = {Netherlands},
year = {Wed Jun 01 00:00:00 EDT 2016},
month = {Wed Jun 01 00:00:00 EDT 2016}
}
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https://doi.org/10.1016/j.trac.2015.09.011
https://doi.org/10.1016/j.trac.2015.09.011
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Works referenced in this record:
Vascular biology of ageing—Implications in hypertension
journal, June 2015
- Harvey, Adam; Montezano, Augusto C.; Touyz, Rhian M.
- Journal of Molecular and Cellular Cardiology, Vol. 83
A novel classification system for evolutionary aging theories
journal, January 2013
- Trindade, Lucas S.; Aigaki, Toshiro; Peixoto, Alexandre A.
- Frontiers in Genetics, Vol. 4
Proteomic quantification and identification of carbonylated proteins upon oxidative stress and during cellular aging
journal, October 2013
- Baraibar, Martin A.; Ladouce, Romain; Friguet, Bertrand
- Journal of Proteomics, Vol. 92
Metabolite profiles and the risk of developing diabetes
journal, March 2011
- Wang, Thomas J.; Larson, Martin G.; Vasan, Ramachandran S.
- Nature Medicine, Vol. 17, Issue 4
Comparative proteomic analysis of human oral fluids according to gender and age: Salivary protein expression according to gender and age
journal, June 2010
- Fleissig, Y.; Reichenberg, E.; Redlich, M.
- Oral Diseases, Vol. 16, Issue 8
Lipidomics of familial longevity
journal, April 2013
- Gonzalez‐Covarrubias, Vanessa; Beekman, Marian; Uh, Hae‐Won
- Aging Cell, Vol. 12, Issue 3
Proteomic urinary biomarker approach in renal disease: from discovery to implementation
journal, March 2014
- Schanstra, Joost P.; Mischak, Harald
- Pediatric Nephrology, Vol. 30, Issue 5
Theories of biological aging: Genes, proteins, and free radicals
journal, January 2006
- Rattan, Suresh I. S.
- Free Radical Research, Vol. 40, Issue 12
Genomics of human health and aging
journal, December 2011
- Kulminski, Alexander M.; Culminskaya, Irina
- AGE, Vol. 35, Issue 2
A Computer Program for Aligning a cDNA Sequence with a Genomic DNA Sequence
journal, September 1998
- Florea, Liliana; Hartzell, George; Zhang, Zheng
- Genome Research, Vol. 8, Issue 9
KEGG: Kyoto Encyclopedia of Genes and Genomes
journal, January 2000
- Kanehisa, Minoru; Goto, Susumu
- Nucleic Acids Research, Vol. 28, Issue 1, p. 27-30
From cellular senescence to Alzheimer’s disease: The role of telomere shortening
journal, July 2015
- Boccardi, Virginia; Pelini, Luca; Ercolani, Sara
- Ageing Research Reviews, Vol. 22
AgeFactDB—the JenAge Ageing Factor Database—towards data integration in ageing research
journal, November 2013
- Hühne, Rolf; Thalheim, Torsten; Sühnel, Jürgen
- Nucleic Acids Research, Vol. 42, Issue D1
Gene expression profiles of single human mature oocytes in relation to age
journal, February 2010
- Grøndahl, M. L.; Yding Andersen, C.; Bogstad, J.
- Human Reproduction, Vol. 25, Issue 4
Human Ageing Genomic Resources: Integrated databases and tools for the biology and genetics of ageing
journal, November 2012
- Tacutu, Robi; Craig, Thomas; Budovsky, Arie
- Nucleic Acids Research, Vol. 41, Issue D1
Biomarkers of healthy ageing: expectations and validation
journal, May 2014
- Martin-Ruiz, Carmen; von Zglinicki, Thomas
- Proceedings of the Nutrition Society, Vol. 73, Issue 3
SignalP 4.0: discriminating signal peptides from transmembrane regions
journal, September 2011
- Petersen, Thomas Nordahl; Brunak, Søren; von Heijne, Gunnar
- Nature Methods, Vol. 8, Issue 10
Characterization of the Yeast Transcriptome
journal, January 1997
- Velculescu, Victor E.; Zhang, Lin; Zhou, Wei
- Cell, Vol. 88, Issue 2
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
journal, September 1997
- Altschul, Stephen F.; Madden, Thomas L.; Schäffer, Alejandro A.
- Nucleic Acids Research, Vol. 25, Issue 17, p. 3389-3402
Cerebrospinal Fluid Metabolome in Mood Disorders-Remission State has a Unique Metabolic Profile
journal, September 2012
- Kaddurah-Daouk, Rima; Yuan, Peixiong; Boyle, Stephen H.
- Scientific Reports, Vol. 2, Issue 1
Global metabolic profiling of animal and human tissues via UPLC-MS
journal, December 2012
- Want, Elizabeth J.; Masson, Perrine; Michopoulos, Filippos
- Nature Protocols, Vol. 8, Issue 1
Metabolomics: from small molecules to big ideas
journal, January 2011
- Baker, Monya
- Nature Methods, Vol. 8, Issue 2
Metabolite identification via the Madison Metabolomics Consortium Database
journal, February 2008
- Cui, Qiu; Lewis, Ian A.; Hegeman, Adrian D.
- Nature Biotechnology, Vol. 26, Issue 2
Metabolomics approach of infant formula for the evaluation of contamination and degradation using hydrophilic interaction liquid chromatography coupled with mass spectrometry
journal, August 2015
- Inoue, Koichi; Tanada, Chihiro; Sakamoto, Tasuku
- Food Chemistry, Vol. 181
Ageing as developmental decay: insights from p16INK4a
journal, December 2014
- Martin, Nadine; Beach, David; Gil, Jesús
- Trends in Molecular Medicine, Vol. 20, Issue 12
FlyBase: enhancing Drosophila Gene Ontology annotations
journal, January 2009
- Tweedie, S.; Ashburner, M.; Falls, K.
- Nucleic Acids Research, Vol. 37, Issue Database
Comparative pathway and network analysis of brain transcriptome changes during adult aging and in Parkinson's disease
journal, February 2015
- Glaab, Enrico; Schneider, Reinhard
- Neurobiology of Disease, Vol. 74
The EMBL Nucleotide Sequence Database
journal, December 2004
- Kanz, C.
- Nucleic Acids Research, Vol. 33, Issue Database issue
Evolution of the Urinary Proteome During Human Renal Development and Maturation
book, October 2014
- Wang, Zi; Li, Mingxi
- Urine Proteomics in Kidney Disease Biomarker Discovery
On the programmed/non-programmed aging controversy
journal, July 2012
- Goldsmith, T. C.
- Biochemistry (Moscow), Vol. 77, Issue 7
Let Me Count the Ways: Mechanisms of Gene Regulation by miRNAs and siRNAs
journal, January 2008
- Wu, Ligang; Belasco, Joel G.
- Molecular Cell, Vol. 29, Issue 1
Aging, Cellular Senescence, and Cancer
journal, February 2013
- Campisi, Judith
- Annual Review of Physiology, Vol. 75, Issue 1
Increased levels of lipid oxidation products in low density lipoproteins of patients suffering from rheumatoid arthritis
journal, May 1997
- Jira, Wolfgang; Spiteller, Gerhard; Richter, Andreas
- Chemistry and Physics of Lipids, Vol. 87, Issue 1
Kidney tissue proteomics reveals regucalcin downregulation in response to diabetic nephropathy with reflection in urinary exosomes
journal, November 2015
- Zubiri, Irene; Posada-Ayala, Maria; Benito-Martin, Alberto
- Translational Research, Vol. 166, Issue 5
Free Radical Involvement in Aging: Pathophysiology and Therapeutic Implications
journal, January 1993
- Harman, Denham
- Drugs & Aging, Vol. 3, Issue 1
Transcriptome-Wide Assessment of Human Brain and Lymphocyte Senescence
journal, August 2008
- Hong, Mun-Gwan; Myers, Amanda J.; Magnusson, Patrik K. E.
- PLoS ONE, Vol. 3, Issue 8
Quantitative metabolic profiling based on gas chromatography.
journal, October 1978
- Gates, S. C.; Sweeley, C. C.
- Clinical Chemistry, Vol. 24, Issue 10
Aging is not programmed: Genetic pseudo-program is a shadow of developmental growth
journal, December 2013
- Blagosklonny, Mikhail V.
- Cell Cycle, Vol. 12, Issue 24
Mass spectrometry-based proteomic analysis of middle-aged vs. aged vastus lateralis reveals increased levels of carbonic anhydrase isoform 3 in senescent human skeletal muscle
journal, July 2012
- Staunton, Lisa; Zweyer, Margit; Swandulla, Dieter
- International Journal of Molecular Medicine, Vol. 30, Issue 4
LongevityMap: a database of human genetic variants associated with longevity
journal, October 2013
- Budovsky, Arie; Craig, Thomas; Wang, Jingwei
- Trends in Genetics, Vol. 29, Issue 10
Enhancing metabolomics research through data mining
journal, September 2015
- Martínez-Arranz, Ibon; Mayo, Rebeca; Pérez-Cormenzana, Miriam
- Journal of Proteomics, Vol. 127
The Crosslinkage Theory of Aging
journal, April 1968
- Bjorksten, Johan
- Journal of the American Geriatrics Society, Vol. 16, Issue 4
Improvements in protein secondary structure prediction by an enhanced neural network
journal, July 1990
- Kneller, D. G.; Cohen, F. E.; Langridge, R.
- Journal of Molecular Biology, Vol. 214, Issue 1
A perspective on proteomics in cell biology
journal, April 2014
- Ahmad, Yasmeen; Lamond, Angus I.
- Trends in Cell Biology, Vol. 24, Issue 4
Metabolomic Fingerprinting: Challenges and Opportunities
journal, January 2013
- Kosmides, Alyssa K.; Kamisoglu, Kubra; Calvano, Steve E.
- Critical Reviews in Biomedical Engineering, Vol. 41, Issue 3
RNA-Seq: a revolutionary tool for transcriptomics
journal, January 2009
- Wang, Zhong; Gerstein, Mark; Snyder, Michael
- Nature Reviews Genetics, Vol. 10, Issue 1
Ensembl 2012
journal, November 2011
- Flicek, P.; Amode, M. R.; Barrell, D.
- Nucleic Acids Research, Vol. 40, Issue D1
Trendspotting in the Protein Data Bank
journal, January 2013
- Berman, Helen M.; Coimbatore Narayanan, Buvaneswari; Costanzo, Luigi Di
- FEBS Letters, Vol. 587, Issue 8
MARK-AGE biomarkers of ageing
journal, November 2015
- Bürkle, Alexander; Moreno-Villanueva, María; Bernhard, Jürgen
- Mechanisms of Ageing and Development, Vol. 151
Theories of ageing
journal, January 2007
- Viña, Jose; Borrás, Consuelo; Miquel, Jaime
- IUBMB Life, Vol. 59, Issue 4
The role of protein and peptide separation before mass spectrometry analysis in clinical proteomics
journal, February 2015
- Camerini, Serena; Mauri, Pierluigi
- Journal of Chromatography A, Vol. 1381
Integromics network meta-analysis on cardiac aging offers robust multi-layer modular signatures and reveals micronome synergism
journal, January 2015
- Dimitrakopoulou, Konstantina; Vrahatis, Aristidis G.; Bezerianos, Anastasios
- BMC Genomics, Vol. 16, Issue 1
Identification of Rack1, EF-Tu and Rhodanese as Aging-Related Proteins in Human Colonic Epithelium by Proteomic Analysis
journal, January 2010
- Yi, Hong; Li, Xin-Hui; Yi, Bin
- Journal of Proteome Research, Vol. 9, Issue 3
Antimicrobial peptides: an alternative for innovative medicines?
journal, January 2015
- da Costa, João Pinto; Cova, Marta; Ferreira, Rita
- Applied Microbiology and Biotechnology, Vol. 99, Issue 5
A Transcriptional Profile of Aging in the Human Kidney
journal, November 2004
- Rodwell, Graham E. J.; Sonu, Rebecca; Zahn, Jacob M.
- PLoS Biology, Vol. 2, Issue 12
The UniProtKB/Swiss-Prot knowledgebase and its Plant Proteome Annotation Program
journal, April 2009
- Schneider, Michel; Lane, Lydie; Boutet, Emmanuel
- Journal of Proteomics, Vol. 72, Issue 3
Proteome analysis in the assessment of ageing
journal, November 2014
- Nkuipou-Kenfack, Esther; Koeck, Thomas; Mischak, Harald
- Ageing Research Reviews, Vol. 18
A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing
journal, June 2007
- Landgraf, Pablo; Rusu, Mirabela; Sheridan, Robert
- Cell, Vol. 129, Issue 7
GMD@CSB.DB: the Golm Metabolome Database
journal, December 2004
- Kopka, J.; Schauer, N.; Krueger, S.
- Bioinformatics, Vol. 21, Issue 8
The human urinary proteome reveals high similarity between kidney aging and chronic kidney disease
journal, April 2009
- Zürbig, Petra; Decramer, Stéphane; Dakna, Mohammed
- PROTEOMICS, Vol. 9, Issue 8
New Approaches to Comparative and Animal Stress Biology Research in the Post-genomic Era: A Contextual Overview
journal, September 2014
- Biggar, Kyle K.; Storey, Kenneth B.
- Computational and Structural Biotechnology Journal, Vol. 11, Issue 19
Role of epoxyeicosatrienoic acids in protecting the myocardium following ischemia/reperfusion injury
journal, January 2007
- Seubert, John M.; Zeldin, Darryl C.; Nithipatikom, Kasem
- Prostaglandins & Other Lipid Mediators, Vol. 82, Issue 1-4
The 2013 SFRBM discovery award: Selected discoveries from the butterfield laboratory of oxidative stress and its sequela in brain in cognitive disorders exemplified by Alzheimer disease and chemotherapy induced cognitive impairment
journal, September 2014
- Butterfield, D. Allan
- Free Radical Biology and Medicine, Vol. 74
SCRATCH: a protein structure and structural feature prediction server
journal, July 2005
- Cheng, J.; Randall, A. Z.; Sweredoski, M. J.
- Nucleic Acids Research, Vol. 33, Issue Web Server
The proteome of erythrocyte-derived microparticles from plasma: new clues for erythrocyte aging and vesiculation
journal, December 2012
- Bosman, Giel J. C. G. M.; Lasonder, Edwin; Groenen-Döpp, Yvonne A. M.
- Journal of Proteomics, Vol. 76
Transcriptional Profiling of Aging in Human Muscle Reveals a Common Aging Signature
journal, July 2006
- Zahn, Jacob M.; Sonu, Rebecca; Vogel, Hannes
- PLoS Genetics, Vol. 2, Issue 7
Urine proteomes of healthy aging humans reveal extracellular matrix (ECM) alterations and immune system dysfunction
journal, August 2013
- Bakun, M.; Senatorski, G.; Rubel, T.
- AGE, Vol. 36, Issue 1
Post-translational Modifications and Mass Spectrometry Detection
journal, December 2013
- Silva, André M. N.; Vitorino, Rui; Domingues, M. Rosário M.
- Free Radical Biology and Medicine, Vol. 65
Musite, a Tool for Global Prediction of General and Kinase-specific Phosphorylation Sites
journal, December 2010
- Gao, Jianjiong; Thelen, Jay J.; Dunker, A. Keith
- Molecular & Cellular Proteomics, Vol. 9, Issue 12
The 1000 Genomes Project: data management and community access
journal, April 2012
- Clarke, Laura; Zheng-Bradley, Xiangqun; Smith, Richard
- Nature Methods, Vol. 9, Issue 5
The etiology of age-related dementia is more complicated than we think
journal, December 2010
- McDonald, Robert J.; Craig, Laura A.; Hong, Nancy S.
- Behavioural Brain Research, Vol. 214, Issue 1
Finishing the euchromatic sequence of the human genome
journal, October 2004
- ,
- Nature, Vol. 431, Issue 7011, p. 931-945
Metabolomics analysis reveals insights into biochemical mechanisms of mental stress-induced left ventricular dysfunction
journal, September 2014
- Boyle, Stephen H.; Matson, Wayne R.; Velazquez, Eric J.
- Metabolomics, Vol. 11, Issue 3
Metabonomics
journal, October 2008
- Nicholson, Jeremy K.; Lindon, John C.
- Nature, Vol. 455, Issue 7216
Mapping cis- and trans-regulatory effects across multiple tissues in twins
journal, September 2012
- Grundberg, Elin; Small, Kerrin S.; Hedman, Åsa K.
- Nature Genetics, Vol. 44, Issue 10
Characterising neural signatures of successful aging: Electrophysiological correlates of preserved episodic memory in older age
journal, July 2015
- Dockree, Paul M.; Brennan, Sabina; O’Sullivan, Michael
- Brain and Cognition, Vol. 97
A graphical representation of protein based on a novel iterated function system
journal, June 2014
- Ma, Tingting; Liu, Yuxin; Dai, Qi
- Physica A: Statistical Mechanics and its Applications, Vol. 403
Age ≥60years was an independent risk factor for diabetes-related complications despite good control of cardiovascular risk factors in patients with type 2 diabetes mellitus
journal, May 2013
- Chew, Boon How; Shariff Ghazali, Sazlina; Ismail, Mastura
- Experimental Gerontology, Vol. 48, Issue 5
DNA damage and repair in telomeres: relation to aging.
journal, January 1995
- Kruk, P. A.; Rampino, N. J.; Bohr, V. A.
- Proceedings of the National Academy of Sciences, Vol. 92, Issue 1
Genetic variation in human telomerase is associated with telomere length in Ashkenazi centenarians
journal, November 2009
- Atzmon, G.; Cho, M.; Cawthon, R. M.
- Proceedings of the National Academy of Sciences, Vol. 107, Issue suppl_1
Omics technologies and the study of human ageing
journal, August 2013
- Valdes, Ana M.; Glass, Daniel; Spector, Tim D.
- Nature Reviews Genetics, Vol. 14, Issue 9
GenBank
journal, November 2012
- Benson, Dennis A.; Cavanaugh, Mark; Clark, Karen
- Nucleic Acids Research, Vol. 41, Issue D1
Correction: Metabolic Signatures of Extreme Longevity in Northern Italian Centenarians Reveal a Complex Remodeling of Lipids, Amino Acids, and Gut Microbiota Metabolism
journal, August 2013
- Collino, Sebastiano; Montoliu, Ivan; Martin, François-Pierre J.
- PLoS ONE, Vol. 8, Issue 8
Metabolomics in cell culture—A strategy to study crucial metabolic pathways in cancer development and the response to treatment
journal, December 2014
- Halama, Anna
- Archives of Biochemistry and Biophysics, Vol. 564
Bionanoconjugation for Proteomics applications — An overview
journal, September 2014
- da Costa, João Pinto; Oliveira-Silva, Rui; Daniel-da-Silva, Ana Luísa
- Biotechnology Advances, Vol. 32, Issue 5
Microbial–Mammalian Cometabolites Dominate the Age-associated Urinary Metabolic Phenotype in Taiwanese and American Populations
journal, June 2013
- Swann, Jonathan R.; Spagou, Konstantina; Lewis, Matthew
- Journal of Proteome Research, Vol. 12, Issue 7
Metabolomics in Nephrotoxicity
book, January 2014
- Zhao, Ying-Yong; Lin, Rui-Chao
- Advances in Clinical Chemistry
Aging Theories and the Zero-Sum Game
journal, February 2014
- Goldsmith, Theodore C.
- Rejuvenation Research, Vol. 17, Issue 1
Mitochondria: In Sickness and in Health
journal, March 2012
- Nunnari, Jodi; Suomalainen, Anu
- Cell, Vol. 148, Issue 6
NCBI reference sequences (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins
journal, January 2007
- Pruitt, K. D.; Tatusova, T.; Maglott, D. R.
- Nucleic Acids Research, Vol. 35, Issue Database
Initial sequencing and analysis of the human genome
journal, February 2001
- Lander, Eric S.; Linton, Lauren M.
- Nature, Vol. 409, Issue 6822, p. 860-921
Widespread splicing changes in human brain development and aging
journal, January 2013
- Mazin, Pavel; Xiong, Jieyi; Liu, Xiling
- Molecular Systems Biology, Vol. 9, Issue 1
Cellular Metabolism and Disease: What Do Metabolic Outliers Teach Us?
journal, March 2012
- DeBerardinis, Ralph J.; Thompson, Craig B.
- Cell, Vol. 148, Issue 6
PhosPhAt: a database of phosphorylation sites in Arabidopsis thaliana and a plant-specific phosphorylation site predictor
journal, December 2007
- Heazlewood, J. L.; Durek, P.; Hummel, J.
- Nucleic Acids Research, Vol. 36, Issue Database
MicroRNAs and their roles in aging
journal, January 2012
- Smith-Vikos, T.; Slack, F. J.
- Journal of Cell Science, Vol. 125, Issue 1
Computational approaches to selecting and optimising targets for structural biology
journal, September 2011
- Overton, Ian M.; Barton, Geoffrey J.
- Methods, Vol. 55, Issue 1
Advantages of combined transmembrane topology and signal peptide prediction--the Phobius web server
journal, May 2007
- Kall, L.; Krogh, A.; Sonnhammer, E. L. L.
- Nucleic Acids Research, Vol. 35, Issue Web Server
Emerging field of metabolomics: Big promise for cancer biomarker identification and drug discovery
journal, March 2015
- Patel, Seema; Ahmed, Shadab
- Journal of Pharmaceutical and Biomedical Analysis, Vol. 107
Association of FOXO3A variation with human longevity confirmed in German centenarians
journal, February 2009
- Flachsbart, Friederike; Caliebe, Amke; Kleindorp, Rabea
- Proceedings of the National Academy of Sciences, Vol. 106, Issue 8
Genome-wide miRNA signatures of human longevity: miRNAs in long-lived individuals
journal, May 2012
- ElSharawy, Abdou; Keller, Andreas; Flachsbart, Friederike
- Aging Cell, Vol. 11, Issue 4
Genetics and genomics of human ageing
journal, January 2011
- Wheeler, Heather E.; Kim, Stuart K.
- Philosophical Transactions of the Royal Society B: Biological Sciences, Vol. 366, Issue 1561
Metabolomics for laboratory diagnostics
journal, September 2015
- Bujak, Renata; Struck-Lewicka, Wiktoria; Markuszewski, Michał J.
- Journal of Pharmaceutical and Biomedical Analysis, Vol. 113
Next-generation sequencing in aging research: Emerging applications, problems, pitfalls and possible solutions
journal, July 2010
- de Magalhães, João Pedro; Finch, Caleb E.; Janssens, Georges
- Ageing Research Reviews, Vol. 9, Issue 3
Oxidative proteome modifications target specific cellular pathways during oxidative stress, cellular senescence and aging
journal, July 2013
- Baraibar, Martin A.; Friguet, Bertrand
- Experimental Gerontology, Vol. 48, Issue 7
Toward rational protein crystallization: A Web server for the design of crystallizable protein variants
journal, August 2007
- Goldschmidt, Lukasz; Cooper, David R.; Derewenda, Zygmunt S.
- Protein Science, Vol. 16, Issue 8
Can We Delay Aging? The Biology and Science of Aging
journal, December 2005
- Anton, B.
- Annals of the New York Academy of Sciences, Vol. 1057, Issue 1
Epigenetics of Aging and Aging-related Disease
journal, May 2014
- Brunet, A.; Berger, S. L.
- The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, Vol. 69, Issue Suppl 1
The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
journal, May 2015
- Ardlie, K. G.; Deluca, D. S.; Segre, A. V.
- Science, Vol. 348, Issue 6235
Understanding fibroblast heterogeneity in the skin
journal, February 2015
- Driskell, Ryan R.; Watt, Fiona M.
- Trends in Cell Biology, Vol. 25, Issue 2
Integrating -Omics: Systems Biology as Explored Through C. elegans Research
journal, October 2015
- Van Assche, Roel; Broeckx, Valérie; Boonen, Kurt
- Journal of Molecular Biology, Vol. 427, Issue 21
Gene expression changes with age in skin, adipose tissue, blood and brain
journal, January 2013
- Glass, Daniel; Viñuela, Ana; Davies, Matthew N.
- Genome Biology, Vol. 14, Issue 7
miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging
journal, April 2010
- Hackl, Matthias; Brunner, Stefan; Fortschegger, Klaus
- Aging Cell, Vol. 9, Issue 2
Molecular responses in the telomere-mitochondrial axis of ageing in the elderly: A candidate gene approach
journal, January 2015
- Pieters, Nicky; Janssen, Bram G.; Valeri, Linda
- Mechanisms of Ageing and Development, Vol. 145
Proteomic profiling reveals a catalogue of new candidate proteins for human skin aging: Proteomic profiling of human skin aging
journal, September 2010
- Laimer, Martin; Kocher, Thomas; Chiocchetti, Andreas
- Experimental Dermatology, Vol. 19, Issue 10
An Attempt at a Rational Classification of Theories of Ageing
journal, August 1990
- Medvedev, Zhores A.
- Biological Reviews, Vol. 65, Issue 3
Aging without Apolipoprotein D: Molecular and cellular modifications in the hippocampus and cortex
journal, July 2015
- Sanchez, Diego; Bajo-Grañeras, Raquel; Del Caño-Espinel, Manuela
- Experimental Gerontology, Vol. 67
Changes in proteomic profiles in different prostate lobes of male rats throughout growth and development and aging stages of the life span
journal, August 2012
- Das, Arunangshu; Bortner, James D.; Aliaga, Cesar A.
- The Prostate, Vol. 73, Issue 4
METLIN: A Metabolite Mass Spectral Database
journal, January 2005
- Smith, Colin A.; Maille, Grace O??; Want, Elizabeth J.
- Therapeutic Drug Monitoring, Vol. 27, Issue 6
Plasma biomarkers of mouse aging
journal, September 2010
- Ding, Juan; Kopchick, John J.
- AGE, Vol. 33, Issue 3
Age impact on clinical risk factors does not justify the age related change in referral pattern for osteoporosis assessment—Data from the Aalborg University Hospital Record for Osteoporosis Risk Assessment (AURORA)
journal, March 2015
- Andersen, Stig; Laurberg, Peter
- Maturitas, Vol. 80, Issue 3
Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry
journal, June 2011
- Dunn, Warwick B.; Broadhurst, David; Begley, Paul
- Nature Protocols, Vol. 6, Issue 7
Understanding the Odd Science of Aging
journal, February 2005
- Kirkwood, Thomas B. L.
- Cell, Vol. 120, Issue 4
Human infant saliva peptidome is modified with age and diet transition
journal, June 2012
- Morzel, Martine; Jeannin, Aline; Lucchi, Géraldine
- Journal of Proteomics, Vol. 75, Issue 12
Brain Derived Neurotrophic Factor (BDNF) Expression Is Regulated by MicroRNAs miR-26a and miR-26b Allele-Specific Binding
journal, December 2011
- Caputo, Viviana; Sinibaldi, Lorenzo; Fiorentino, Alessia
- PLoS ONE, Vol. 6, Issue 12
Metabolomic markers reveal novel pathways of ageing and early development in human populations
journal, June 2013
- Menni, Cristina; Kastenmüller, Gabriella; Petersen, Ann Kristin
- International Journal of Epidemiology, Vol. 42, Issue 4
Methods for Building Quantitative Structure–Activity Relationship (QSAR) Descriptors and Predictive Models for Computer-Aided Design of Antimicrobial Peptides
book, September 2009
- Taboureau, Olivier
- Methods in Molecular Biology
Global Proteomics Remodeling of Cardiac Aging and Pressure-Overload Induced Heart Failure is Attenuated by Suppression rf Target of Rapamycin
journal, April 2014
- Dai, Dao-Fu
- Journal of the American College of Cardiology, Vol. 63, Issue 12
The emergence of metabolomics as a key discipline in the drug discovery process
journal, June 2015
- Fillet, Marianne; Frédérich, Michel
- Drug Discovery Today: Technologies, Vol. 13
Normalization, testing, and false discovery rate estimation for RNA-sequencing data
journal, October 2011
- Li, J.; Witten, D. M.; Johnstone, I. M.
- Biostatistics, Vol. 13, Issue 3
Epigenetics and aging
journal, February 2013
- D’Aquila, Patrizia; Rose, Giuseppina; Bellizzi, Dina
- Maturitas, Vol. 74, Issue 2
NMR-based metabolomics approach to study the toxicity of lambda-cyhalothrin to goldfish (Carassius auratus)
journal, January 2014
- Li, Minghui; Wang, Junsong; Lu, Zhaoguang
- Aquatic Toxicology, Vol. 146
The Rat Genome Database, update 2007--Easing the path from disease to data and back again
journal, January 2007
- Twigger, S. N.; Shimoyama, M.; Bromberg, S.
- Nucleic Acids Research, Vol. 35, Issue Database
deepBase: a database for deeply annotating and mining deep sequencing data
journal, December 2009
- Yang, Jian-Hua; Shao, Peng; Zhou, Hui
- Nucleic Acids Research, Vol. 38, Issue suppl_1
Sensitivity and Selectivity in Protein Similarity Searches: A Comparison of Smith–Waterman in Hardware to BLAST and FASTA
journal, December 1996
- Shpaer, Eugene G.; Robinson, Max; Yee, David
- Genomics, Vol. 38, Issue 2
Transcriptomic profiles of aging in purified human immune cells
journal, April 2015
- Reynolds, Lindsay M.; Ding, Jingzhong; Taylor, Jackson R.
- BMC Genomics, Vol. 16, Issue 1
voom: precision weights unlock linear model analysis tools for RNA-seq read counts
journal, January 2014
- Law, Charity W.; Chen, Yunshun; Shi, Wei
- Genome Biology, Vol. 15, Issue 2
Modern evolutionary mechanics theories and resolving the programmed/non-programmed aging controversy
journal, October 2014
- Goldsmith, Theodore C.
- Biochemistry (Moscow), Vol. 79, Issue 10
Association of the FOXO3A Locus with Extreme Longevity in a Southern Italian Centenarian Study
journal, April 2009
- Anselmi, Chiara Viviani; Malovini, Alberto; Roncarati, Roberta
- Rejuvenation Research, Vol. 12, Issue 2
EMBOSS: The European Molecular Biology Open Software Suite
journal, June 2000
- Rice, Peter; Longden, Ian; Bleasby, Alan
- Trends in Genetics, Vol. 16, Issue 6
Human serum metabolic profiles are age dependent
journal, August 2012
- Yu, Zhonghao; Zhai, Guangju; Singmann, Paula
- Aging Cell, Vol. 11, Issue 6
Synaptic genes are extensively downregulated across multiple brain regions in normal human aging and Alzheimer's disease
journal, June 2013
- Berchtold, Nicole C.; Coleman, Paul D.; Cribbs, David H.
- Neurobiology of Aging, Vol. 34, Issue 6
Arguments against non-programmed aging theories
journal, September 2013
- Goldsmith, T. C.
- Biochemistry (Moscow), Vol. 78, Issue 9
1H NMR metabolomics analysis of the effect of dichloroacetate and allopurinol on breast cancers
journal, May 2014
- Lefort, Natalie; Brown, Amy; Lloyd, Vett
- Journal of Pharmaceutical and Biomedical Analysis, Vol. 93
HMDB 3.0—The Human Metabolome Database in 2013
journal, November 2012
- Wishart, David S.; Jewison, Timothy; Guo, An Chi
- Nucleic Acids Research, Vol. 41, Issue D1
A comprehensive evaluation of normalization methods for Illumina high-throughput RNA sequencing data analysis
journal, September 2012
- Dillies, M. -A.; Rau, A.; Aubert, J.
- Briefings in Bioinformatics, Vol. 14, Issue 6
Meta-analysis of age-related gene expression profiles identifies common signatures of aging
journal, February 2009
- de Magalhães, João Pedro; Curado, João; Church, George M.
- Bioinformatics, Vol. 25, Issue 7
A Parsimonious Model for Gene Regulation by miRNAs
journal, February 2011
- Djuranovic, S.; Nahvi, A.; Green, R.
- Science, Vol. 331, Issue 6017
ZFIN: enhancements and updates to the zebrafish model organism database
journal, October 2010
- Bradford, Y.; Conlin, T.; Dunn, N.
- Nucleic Acids Research, Vol. 39, Issue Database
Protein intake and exercise for optimal muscle function with aging: Recommendations from the ESPEN Expert Group
journal, December 2014
- Deutz, Nicolaas E. P.; Bauer, Jürgen M.; Barazzoni, Rocco
- Clinical Nutrition, Vol. 33, Issue 6
Roy Walford and the immunologic theory of aging
journal, April 2005
- Effros, Rita B.
- Immunity & Ageing, Vol. 2, Issue 1