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Title: The increase in animal mortality risk following exposure to sparsely ionizing radiation is not linear quadratic with dose

The US government regulates allowable radiation exposures relying, in large part, on the seventh report from the committee to estimate the Biological Effect of Ionizing Radiation (BEIR VII), which estimated that most contemporary exposures- protracted or low-dose, carry 1.5 fold less risk of carcinogenesis and mortality per Gy than acute exposures of atomic bomb survivors. This correction is known as the dose and dose rate effectiveness factor for the life span study of atomic bomb survivors (DDREFLSS). As a result, it was calculated by applying a linear-quadratic dose response model to data from Japanese atomic bomb survivors and a limited number of animal studies.
Authors:
 [1] ;  [1] ;  [2] ;  [1] ;  [3]
  1. Northwestern Univ., Chicago, IL (United States)
  2. Univ. of Chicago, Chicago, IL (United States)
  3. Univ. of Oklahoma, Norman, OK (United States)
Publication Date:
OSTI Identifier:
1240244
Grant/Contract Number:
SC0001271
Type:
Accepted Manuscript
Journal Name:
PLoS ONE
Additional Journal Information:
Journal Volume: 10; Journal Issue: 12; Journal ID: ISSN 1932-6203
Publisher:
Public Library of Science
Research Org:
Northwestern Univ., Chicago, IL (United States)
Sponsoring Org:
USDOE Office of Science (SC)
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT. bombs; death rates; radiation exposure; carcinogenesis; dose prediction methods; animal studies; archives; ionizing radiation