Computational protein design enables a novel one-carbon assimilation pathway
- Authors:
- Publication Date:
- Sponsoring Org.:
- USDOE Advanced Research Projects Agency - Energy (ARPA-E)
- OSTI Identifier:
- 1235188
- Grant/Contract Number:
- AC02-05CH11231; AR0000091
- Resource Type:
- Published Article
- Journal Name:
- Proceedings of the National Academy of Sciences of the United States of America
- Additional Journal Information:
- Journal Name: Proceedings of the National Academy of Sciences of the United States of America Journal Volume: 112 Journal Issue: 12; Journal ID: ISSN 0027-8424
- Publisher:
- National Academy of Sciences, Washington, DC (United States)
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Siegel, Justin B., Smith, Amanda Lee, Poust, Sean, Wargacki, Adam J., Bar-Even, Arren, Louw, Catherine, Shen, Betty W., Eiben, Christopher B., Tran, Huu M., Noor, Elad, Gallaher, Jasmine L., Bale, Jacob, Yoshikuni, Yasuo, Gelb, Michael H., Keasling, Jay D., Stoddard, Barry L., Lidstrom, Mary E., and Baker, David. Computational protein design enables a novel one-carbon assimilation pathway. United States: N. p., 2015.
Web. doi:10.1073/pnas.1500545112.
Siegel, Justin B., Smith, Amanda Lee, Poust, Sean, Wargacki, Adam J., Bar-Even, Arren, Louw, Catherine, Shen, Betty W., Eiben, Christopher B., Tran, Huu M., Noor, Elad, Gallaher, Jasmine L., Bale, Jacob, Yoshikuni, Yasuo, Gelb, Michael H., Keasling, Jay D., Stoddard, Barry L., Lidstrom, Mary E., & Baker, David. Computational protein design enables a novel one-carbon assimilation pathway. United States. https://doi.org/10.1073/pnas.1500545112
Siegel, Justin B., Smith, Amanda Lee, Poust, Sean, Wargacki, Adam J., Bar-Even, Arren, Louw, Catherine, Shen, Betty W., Eiben, Christopher B., Tran, Huu M., Noor, Elad, Gallaher, Jasmine L., Bale, Jacob, Yoshikuni, Yasuo, Gelb, Michael H., Keasling, Jay D., Stoddard, Barry L., Lidstrom, Mary E., and Baker, David. Mon .
"Computational protein design enables a novel one-carbon assimilation pathway". United States. https://doi.org/10.1073/pnas.1500545112.
@article{osti_1235188,
title = {Computational protein design enables a novel one-carbon assimilation pathway},
author = {Siegel, Justin B. and Smith, Amanda Lee and Poust, Sean and Wargacki, Adam J. and Bar-Even, Arren and Louw, Catherine and Shen, Betty W. and Eiben, Christopher B. and Tran, Huu M. and Noor, Elad and Gallaher, Jasmine L. and Bale, Jacob and Yoshikuni, Yasuo and Gelb, Michael H. and Keasling, Jay D. and Stoddard, Barry L. and Lidstrom, Mary E. and Baker, David},
abstractNote = {},
doi = {10.1073/pnas.1500545112},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
number = 12,
volume = 112,
place = {United States},
year = {Mon Mar 09 00:00:00 EDT 2015},
month = {Mon Mar 09 00:00:00 EDT 2015}
}
Free Publicly Available Full Text
Publisher's Version of Record
https://doi.org/10.1073/pnas.1500545112
https://doi.org/10.1073/pnas.1500545112
Other availability
Cited by: 196 works
Citation information provided by
Web of Science
Web of Science
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.
Works referenced in this record:
Next generation biofuel engineering in prokaryotes
journal, June 2013
- Gronenberg, Luisa S.; Marcheschi, Ryan J.; Liao, James C.
- Current Opinion in Chemical Biology, Vol. 17, Issue 3
Benzaldehyde lyase, a novel thiamine PPi-requiring enzyme, from Pseudomonas fluorescens biovar I.
journal, May 1989
- González, B.; Vicuña, R.
- Journal of Bacteriology, Vol. 171, Issue 5
Ultrahigh Performance Liquid Chromatography−Tandem Mass Spectrometry Method for Fast and Robust Quantification of Anionic and Aromatic Metabolites
journal, June 2010
- Buescher, Joerg Martin; Moco, Sofia; Sauer, Uwe
- Analytical Chemistry, Vol. 82, Issue 11
Integrated Electromicrobial Conversion of CO2 to Higher Alcohols
journal, March 2012
- Li, H.; Opgenorth, P. H.; Wernick, D. G.
- Science, Vol. 335, Issue 6076, p. 1596-1596
eQuilibrator--the biochemical thermodynamics calculator
journal, November 2011
- Flamholz, A.; Noor, E.; Bar-Even, A.
- Nucleic Acids Research, Vol. 40, Issue D1
The Enzymic Interconversion of Acetate and Acetyl-coenzyme A in Escherichia coli
journal, October 1977
- Brown, T. D. K.; Jones-Mortimer, M. C.; Kornberg, H. L.
- Journal of General Microbiology, Vol. 102, Issue 2
Pathway Thermodynamics Highlights Kinetic Obstacles in Central Metabolism
journal, February 2014
- Noor, Elad; Bar-Even, Arren; Flamholz, Avi
- PLoS Computational Biology, Vol. 10, Issue 2
Electro-reduction of carbon dioxide to formate on lead electrode in aqueous medium
journal, September 2008
- Innocent, B.; Liaigre, D.; Pasquier, D.
- Journal of Applied Electrochemistry, Vol. 39, Issue 2, p. 227-232
De Novo Enzyme Design Using Rosetta3
journal, May 2011
- Richter, Florian; Leaver-Fay, Andrew; Khare, Sagar D.
- PLoS ONE, Vol. 6, Issue 5
Structure and mechanism of the ThDP-dependent benzaldehyde lyase from Pseudomonas fluorescens: ThDP-depending benzaldehyde lyase
journal, November 2005
- Mosbacher, Tanja G.; Mueller, Michael; Schulz, Georg E.
- FEBS Journal, Vol. 272, Issue 23
Computation of metabolic fluxes and efficiencies for biological carbon dioxide fixation
journal, March 2011
- Boyle, Nanette R.; Morgan, John A.
- Metabolic Engineering, Vol. 13, Issue 2
Structure and Mechanisms of a Protein-Based Organelle in Escherichia coli
journal, December 2009
- Tanaka, S.; Sawaya, M. R.; Yeates, T. O.
- Science, Vol. 327, Issue 5961
Metabolic Engineering: Past and Future
journal, June 2013
- Woolston, Benjamin M.; Edgar, Steven; Stephanopoulos, Gregory
- Annual Review of Chemical and Biomolecular Engineering, Vol. 4, Issue 1
Design and analysis of metabolic pathways supporting formatotrophic growth for electricity-dependent cultivation of microbes
journal, August 2013
- Bar-Even, Arren; Noor, Elad; Flamholz, Avi
- Biochimica et Biophysica Acta (BBA) - Bioenergetics, Vol. 1827, Issue 8-9
Isolation and characterization of hypophosphite-resistant mutants of Escherichia coli: identification of the FocA protein, encoded by the pfl operon, as a putative formate transporter
journal, March 1994
- Suppmann, Bernhard; Sawers, Gary
- Molecular Microbiology, Vol. 11, Issue 5
BRENDA, enzyme data and metabolic information
journal, January 2002
- Schomburg, I.
- Nucleic Acids Research, Vol. 30, Issue 1
Engineering Escherichia coli for methanol conversion
journal, March 2015
- Müller, Jonas E. N.; Meyer, Fabian; Litsanov, Boris
- Metabolic Engineering, Vol. 28, p. 190-201
Short N-terminal sequences package proteins into bacterial microcompartments
journal, March 2010
- Fan, C.; Cheng, S.; Liu, Y.
- Proceedings of the National Academy of Sciences, Vol. 107, Issue 16
Engineering BioBrick vectors from BioBrick parts
journal, January 2008
- Shetty, Reshma P.; Endy, Drew; Knight, Thomas F.
- Journal of Biological Engineering, Vol. 2, Article No. 5
Steady-state and pre-steady-state kinetics of coenzyme A-linked aldehyde dehydrogenase from Escherichia coli
journal, December 1981
- Shone, Clifford C.; Fromm, Herbert J.
- Biochemistry, Vol. 20, Issue 26
Metabolic Fluxes during Strong Carbon Catabolite Repression by Malate in Bacillus subtilis
journal, November 2009
- Kleijn, Roelco J.; Buescher, Joerg M.; Le Chat, Ludovic
- Journal of Biological Chemistry, Vol. 285, Issue 3
IsoCor: correcting MS data in isotope labeling experiments
journal, March 2012
- Millard, P.; Letisse, F.; Sokol, S.
- Bioinformatics, Vol. 28, Issue 9
Acetyl-coenzyme A synthetase (AMP forming)
journal, August 2004
- Starai, V. J.; Escalante-Semerena, J. C.
- Cellular and Molecular Life Sciences, Vol. 61, Issue 16
On the mechanism of the formose reaction
journal, January 1959
- Breslow, Ronald
- Tetrahedron Letters, Vol. 1, Issue 21
Manufacturing Molecules Through Metabolic Engineering
journal, December 2010
- Keasling, Jay D.
- Science, Vol. 330, Issue 6009, p. 1355-1358
Increased Diels-Alderase activity through backbone remodeling guided by Foldit players
journal, January 2012
- Eiben, Christopher B.; Siegel, Justin B.; Bale, Jacob B.
- Nature Biotechnology, Vol. 30, Issue 2
Design and analysis of synthetic carbon fixation pathways
journal, April 2010
- Bar-Even, A.; Noor, E.; Lewis, N. E.
- Proceedings of the National Academy of Sciences, Vol. 107, Issue 19, p. 8889-8894
The Electrochemical Reduction of Carbon Dioxide to Formate/Formic Acid: Engineering and Economic Feasibility
journal, September 2011
- Agarwal, Arun S.; Zhai, Yumei; Hill, Davion
- ChemSusChem, Vol. 4, Issue 9
Conserving a Volatile Metabolite: a Role for Carboxysome-Like Organelles in Salmonella enterica
journal, April 2006
- Penrod, J. T.; Roth, J. R.
- Journal of Bacteriology, Vol. 188, Issue 8
Snapshot of a Reaction Intermediate: Analysis of Benzoylformate Decarboxylase in Complex with a Benzoylphosphonate Inhibitor †
journal, April 2009
- Brandt, Gabriel S.; Kneen, Malea M.; Chakraborty, Sumit
- Biochemistry, Vol. 48, Issue 15
Rapid and efficient site-specific mutagenesis without phenotypic selection.
journal, January 1985
- Kunkel, T. A.
- Proceedings of the National Academy of Sciences, Vol. 82, Issue 2, p. 488-492
Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli
journal, June 2009
- Bennett, Bryson D.; Kimball, Elizabeth H.; Gao, Melissa
- Nature Chemical Biology, Vol. 5, Issue 8
Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel
journal, November 2009
- Wang, Yi; Huang, Yongjian; Wang, Jiawei
- Nature, Vol. 462, Issue 7272
EcoCyc: fusing model organism databases with systems biology
journal, November 2012
- Keseler, Ingrid M.; Mackie, Amanda; Peralta-Gil, Martin
- Nucleic Acids Research, Vol. 41, Issue D1