Bio-corrosion and cytotoxicity studies on novel Zr55Co30Ti15 and Cu60Zr20Ti20 metallic glasses

Vincent, S.; Daiwile, A.; Devi, S. S.; Kramer, M. J.; Besser, M. F.; Murty, B. S.; Bhatt, Jatin

doi:10.1007/s11661-014-2574-9

Title: Bio-corrosion and cytotoxicity studies on novel Zr₅₅Co₃₀Ti₁₅ and Cu₆₀Zr₂₀Ti₂₀ metallic glasses

Abstract

Metallic glasses are a potential and compatible implant candidate for biomedical applications. In the present investigation, a comparative study between novel Zr₅₅Co₃₀Ti₁₅ and Cu₆₀Zr₂₀Ti₂₀ metallic glasses is carried out to evaluate in vitro biocompatibility using simulated body fluids. The bio-corrosion behavior of Zr- and Cu-based metallic glasses in different types of artificial body fluids such as artificial saliva solution, phosphate-buffered saline solution, artificial blood plasma solution, and Hank’s balanced saline solution is evaluated using potentiodynamic polarization studies at a constant body temperature of 310.15 K (37 °C). Surface morphology of samples after bio-corrosion experiments was observed by scanning electron microscopy. In vitro cytotoxicity test on glassy alloys were performed using human osteosarcoma cell line as per 10993-5 guidelines from International Organization for Standardization. As a result, the comparative study between Zr- and Cu-based glassy alloys provides vital information about the effect of elemental composition on biocompatibility of metallic glasses.

Authors:

Vincent, S. ^[1]; Daiwile, A. ^[2]; Devi, S. S. ^[2]; Kramer, M. J. ^[3]; Besser, M. F. ^[4]; Murty, B. S. ^[5]; Bhatt, Jatin ^[1]

Visvesvaraya National Institute of Technology, Nagour (India)
National Environmental Engineering Research Institute, Nagpur (India)
Ames Lab., Ames, IA (United States)
Iowa State Univ., Ames, IA (United States)
Indian Inst. of Technology (IIT), Madras (India)

Publication Date:: Fri Sep 26 00:00:00 EDT 2014

Research Org.:: Ames Lab., Ames, IA (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1227146

Report Number(s):: IS-J-8662
Journal ID: ISSN 1073-5623; PII: 2574

Grant/Contract Number:: AC02-07CH11358

Resource Type:: Accepted Manuscript

Journal Name:: Metallurgical and Materials Transactions. A, Physical Metallurgy and Materials Science

Additional Journal Information:: Journal Volume: 46; Journal Issue: 6; Journal ID: ISSN 1073-5623

Publisher:: ASM International

Country of Publication:: United States

Language:: English

Subject:: 36 MATERIALS SCIENCE; 60 APPLIED LIFE SCIENCES; glassy alloy; ho cell; metallic glass; artificial saliva solution; ho cell line; artificial body fluid; SBF solution; melt-spun alloy; potentiodynamic polarization; 316L stainless steel; passive film; osteosarcoma cell line; simulated body fluid; corrosion behavior; cell viability

Citation Formats


                    Vincent, S., Daiwile, A., Devi, S. S., Kramer, M. J., Besser, M. F., Murty, B. S., and Bhatt, Jatin. Bio-corrosion and cytotoxicity studies on novel Zr55Co30Ti15 and Cu60Zr20Ti20 metallic glasses.  United States: N. p., 2014. 
Web.  doi:10.1007/s11661-014-2574-9.

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                    Vincent, S., Daiwile, A., Devi, S. S., Kramer, M. J., Besser, M. F., Murty, B. S., & Bhatt, Jatin. Bio-corrosion and cytotoxicity studies on novel Zr55Co30Ti15 and Cu60Zr20Ti20 metallic glasses.  United States.  https://doi.org/10.1007/s11661-014-2574-9

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                    Vincent, S., Daiwile, A., Devi, S. S., Kramer, M. J., Besser, M. F., Murty, B. S., and Bhatt, Jatin. Fri .  
"Bio-corrosion and cytotoxicity studies on novel Zr55Co30Ti15 and Cu60Zr20Ti20 metallic glasses".  United States.  https://doi.org/10.1007/s11661-014-2574-9.  https://www.osti.gov/servlets/purl/1227146.

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@article{osti_1227146,

  title        = {Bio-corrosion and cytotoxicity studies on novel Zr55Co30Ti15 and Cu60Zr20Ti20 metallic glasses},

  author       = {Vincent, S. and Daiwile, A. and Devi, S. S. and Kramer, M. J. and Besser, M. F. and Murty, B. S. and Bhatt, Jatin},

  abstractNote = {Metallic glasses are a potential and compatible implant candidate for biomedical applications. In the present investigation, a comparative study between novel Zr55Co30Ti15 and Cu60Zr20Ti20 metallic glasses is carried out to evaluate in vitro biocompatibility using simulated body fluids. The bio-corrosion behavior of Zr- and Cu-based metallic glasses in different types of artificial body fluids such as artificial saliva solution, phosphate-buffered saline solution, artificial blood plasma solution, and Hank’s balanced saline solution is evaluated using potentiodynamic polarization studies at a constant body temperature of 310.15 K (37 °C). Surface morphology of samples after bio-corrosion experiments was observed by scanning electron microscopy. In vitro cytotoxicity test on glassy alloys were performed using human osteosarcoma cell line as per 10993-5 guidelines from International Organization for Standardization. As a result, the comparative study between Zr- and Cu-based glassy alloys provides vital information about the effect of elemental composition on biocompatibility of metallic glasses.},

  doi          = {10.1007/s11661-014-2574-9},

  journal      = {Metallurgical and Materials Transactions. A, Physical Metallurgy and Materials Science},

  number       = 6,

  volume       = 46,

  place        = {United States},

  year         = {Fri Sep 26 00:00:00 EDT 2014},

  month        = {Fri Sep 26 00:00:00 EDT 2014}

}

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Works referenced in this record:

Bulk metallic glasses for biomedical applications
journal, September 2009

Schroers, Jan; Kumar, Golden; Hodges, Thomas M.
JOM, Vol. 61, Issue 9
DOI: 10.1007/s11837-009-0128-1

Biocompatibility Study of Zirconium-Based Bulk Metallic Glasses for Orthopedic Applications
journal, January 2010

He, Wei; Chuang, Andrew; Cao, Zheng
Metallurgical and Materials Transactions A, Vol. 41, Issue 7
DOI: 10.1007/s11661-009-0150-5

Study on bio-corrosion and cytotoxicity of a sr-based bulk metallic glass as potential biodegradable metal
journal, November 2011

Li, H. F.; Zhao, K.; Wang, Y. B.
Journal of Biomedical Materials Research Part B: Applied Biomaterials, Vol. 100B, Issue 2
DOI: 10.1002/jbm.b.31958

Responses of bone-forming cells on pre-immersed Zr-based bulk metallic glasses: Effects of composition and roughness
journal, January 2011

Huang, L.; Cao, Z.; Meyer, H. M.
Acta Biomaterialia, Vol. 7, Issue 1
DOI: 10.1016/j.actbio.2010.08.002

Electrochemical behavior of a Ti-based bulk metallic glass
journal, July 2007

Morrison, M. L.; Buchanan, R. A.; Peker, A.
Journal of Non-Crystalline Solids, Vol. 353, Issue 22-23
DOI: 10.1016/j.jnoncrysol.2007.03.012

Ni- and Cu-free Zr–Al–Co–Ag bulk metallic glasses with superior glass-forming ability
journal, February 2011

Hua, Nengbin; Pang, Shujie; Li, Yan
Journal of Materials Research, Vol. 26, Issue 4
DOI: 10.1557/jmr.2010.65

Corrosion behavior and in vitro biocompatibility of Zr–Al–Co–Ag bulk metallic glasses: An experimental case study
journal, July 2012

Hua, Nengbin; Huang, Lu; Wang, Jianfeng
Journal of Non-Crystalline Solids, Vol. 358, Issue 12-13
DOI: 10.1016/j.jnoncrysol.2012.04.022

Zr61Ti2Cu25Al12 metallic glass for potential use in dental implants: Biocompatibility assessment by in vitro cellular responses
journal, May 2013

Li, Jing; Shi, Ling-ling; Zhu, Zhen-dong
Materials Science and Engineering: C, Vol. 33, Issue 4
DOI: 10.1016/j.msec.2013.01.033

Disturbance of DNA damage recognition after UV-irradiation by nickel(II) and cadmium(II) in mammalian cells
journal, April 1998

Hartmann, M.
Carcinogenesis, Vol. 19, Issue 4
DOI: 10.1093/carcin/19.4.617

Bulk metallic glass formation in Zr–Cu–Fe–Al alloys
journal, June 2005

Jin, Kaifeng; Löffler, Jörg F.
Applied Physics Letters, Vol. 86, Issue 24
DOI: 10.1063/1.1948513

Cytotoxicity of Zr-based bulk metallic glasses
journal, July 2006

Buzzi, Stefano; Jin, Kaifeng; Uggowitzer, Peter J.
Intermetallics, Vol. 14, Issue 7
DOI: 10.1016/j.intermet.2005.11.003

MgZnCa glasses without clinically observable hydrogen evolution for biodegradable implants
journal, September 2009

Zberg, Bruno; Uggowitzer, Peter J.; Löffler, Jörg F.
Nature Materials, Vol. 8, Issue 11
DOI: 10.1038/nmat2542

The effect of Nb addition on mechanical properties, corrosion behavior, and metal-ion release of ZrAlCuNi bulk metallic glasses in artificial body fluid
journal, January 2005

Qiu, C. L.; Liu, L.; Sun, M.
Journal of Biomedical Materials Research Part A, Vol. 75A, Issue 4
DOI: 10.1002/jbm.a.30502

A novel Ni-free Zr-based bulk metallic glass with enhanced plasticity and good biocompatibility
journal, October 2006

Qiu, C. L.; Chen, Q.; Liu, L.
Scripta Materialia, Vol. 55, Issue 7
DOI: 10.1016/j.scriptamat.2006.06.018

Enhanced glass forming ability and plasticity of a Ni-free Zr-based bulk metallic glass
journal, November 2009

Liu, Z.; Chan, K. C.; Liu, L.
Journal of Alloys and Compounds, Vol. 487, Issue 1-2
DOI: 10.1016/j.jallcom.2009.08.030

Deformation behavior, corrosion resistance, and cytotoxicity of Ni-free Zr-based bulk metallic glasses
journal, January 2008

Liu, L.; Qiu, C. L.; Chen, Q.
Journal of Biomedical Materials Research Part A, Vol. 86A, Issue 1
DOI: 10.1002/jbm.a.31425

Bio-activation of Ni-free Zr-based bulk metallic glass by surface modification
journal, October 2010

Liu, L.; Chan, K. C.; Yu, Y.
Intermetallics, Vol. 18, Issue 10
DOI: 10.1016/j.intermet.2010.02.039

A Ni-free ZrCuFeAlAg bulk metallic glass with potential for biomedical applications
journal, June 2013

Liu, Yan; Wang, Yi-Mei; Pang, Hui-Fang
Acta Biomaterialia, Vol. 9, Issue 6
DOI: 10.1016/j.actbio.2013.02.019

Corrosion resistance and biocompatibility of Ni-free Zr-based bulk metallic glass for biomedical applications
journal, November 2012

Huang, Her-Hsiung; Sun, Ying-Sui; Wu, Chia-Ping
Intermetallics, Vol. 30
DOI: 10.1016/j.intermet.2012.03.015

Copper toxicity in the general population
journal, April 2010

Brewer, George J.
Clinical Neurophysiology, Vol. 121, Issue 4
DOI: 10.1016/j.clinph.2009.12.015

Corrosion characterization on melt spun Cu60Zr20Ti20 metallic glass: An experimental case study
journal, November 2013

Vincent, S.; Khan, A. F.; Murty, B. S.
Journal of Non-Crystalline Solids, Vol. 379
DOI: 10.1016/j.jnoncrysol.2013.07.007

Bio-corrosion study on zirconium-based bulk-metallic glasses
journal, April 2009

Huang, Lu; Qiao, Dongchun; Green, Brandice A.
Intermetallics, Vol. 17, Issue 4
DOI: 10.1016/j.intermet.2008.07.020

Corrosion resistance of Zr-based bulk amorphous alloys containing Pd
journal, July 2004

Qin, F. X.; Zhang, H. F.; Deng, Y. F.
Journal of Alloys and Compounds, Vol. 375, Issue 1-2
DOI: 10.1016/j.jallcom.2003.12.004

Electrochemical behavior of multicomponent amorphous and nanocrystalline Zr-based alloys in different environments
journal, August 2006

Mondal, K.; Murty, B. S.; Chatterjee, U. K.
Corrosion Science, Vol. 48, Issue 8
DOI: 10.1016/j.corsci.2005.09.001

Micro indentation study on Cu60Zr20Ti20 metallic glass
journal, July 2012

Vincent, S.; Basu, Joysurya; Murty, B. S.
Materials Science and Engineering: A, Vol. 550
DOI: 10.1016/j.msea.2012.04.050

Biomimetic Modification of Porous TiNbZr Alloy Scaffold for Bone Tissue Engineering
journal, January 2010

Wang, Xiaojian; Li, Yuncang; Hodgson, Peter D.
Tissue Engineering Part A, Vol. 16, Issue 1
DOI: 10.1089/ten.tea.2009.0074

Thermodynamic prediction of bulk metallic glass forming alloys in ternary Zr–Cu–X (X=Ag, Al, Ti, Ga) systems
journal, October 2011

Vincent, S.; Peshwe, D. R.; Murty, B. S.
Journal of Non-Crystalline Solids, Vol. 357, Issue 19-20
DOI: 10.1016/j.jnoncrysol.2011.06.024

Thermodynamic Basis for Glass Formation in Cu-Zr Rich Ternary Systems and Their Synthesis by Mechanical Alloying
journal, July 2013

Vincent, S.; Bhatt, Jatin; Murty, B. S.
Metallurgical and Materials Transactions A, Vol. 45, Issue 5
DOI: 10.1007/s11661-013-1855-z

Works referencing / citing this record:

Recent Advancements in Bulk Metallic Glasses and Their Applications: A Review
journal, August 2017

Khan, Muhammad Mudasser; Nemati, Ali; Rahman, Zia Ur
Critical Reviews in Solid State and Materials Sciences, Vol. 43, Issue 3
DOI: 10.1080/10408436.2017.1358149

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Title: Bio-corrosion and cytotoxicity studies on novel Zr55Co30Ti15 and Cu60Zr20Ti20 metallic glasses

Abstract

Citation Formats

Bulk metallic glasses for biomedical applications journal, September 2009

Biocompatibility Study of Zirconium-Based Bulk Metallic Glasses for Orthopedic Applications journal, January 2010

Study on bio-corrosion and cytotoxicity of a sr-based bulk metallic glass as potential biodegradable metal journal, November 2011

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Disturbance of DNA damage recognition after UV-irradiation by nickel(II) and cadmium(II) in mammalian cells journal, April 1998

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Title: Bio-corrosion and cytotoxicity studies on novel Zr₅₅Co₃₀Ti₁₅ and Cu₆₀Zr₂₀Ti₂₀ metallic glasses

Bulk metallic glasses for biomedical applications
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Biocompatibility Study of Zirconium-Based Bulk Metallic Glasses for Orthopedic Applications
journal, January 2010

Study on bio-corrosion and cytotoxicity of a sr-based bulk metallic glass as potential biodegradable metal
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journal, January 2011

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Micro indentation study on Cu60Zr20Ti20 metallic glass
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