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Title: Improved ion optics for introduction of ions into a 9.4-T Fourier transform ion cyclotron resonance mass spectrometer

Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry provides unparalleled mass accuracy and resolving power.[1],[2] With electrospray ionization (ESI), ions are typically transferred into the mass spectrometer through a skimmer, which serves as a conductance-limiting orifice. However, the skimmer allows only a small fraction of incoming ions to enter the mass spectrometer. An ion funnel, originally developed by Smith and coworkers at Pacific Northwest National Laboratory (PNNL)[3-5] provides much more efficient ion focusing and transfer. The large entrance aperture of the ion funnel allows almost all ions emanating from a heated capillary to be efficiently captured and transferred, resulting in nearly lossless transmission.
Authors:
 [1] ;  [2] ;  [1] ;  [3] ;  [2] ;  [2] ;  [2] ;  [2] ;  [4]
  1. Florida State Univ., Tallahassee, FL (United States). National High Magnetic Field Lab. (MagLab), Ion Cyclotron Resonance Program
  2. Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
  3. Florida State Univ., Tallahassee, FL (United States). Dept. of Chemistry and Biochemistry
  4. Florida State Univ., Tallahassee, FL (United States). National High Magnetic Field Lab. (MagLab), Ion Cyclotron Resonance Program; Florida State Univ., Tallahassee, FL (United States). Dept. of Chemistry and Biochemistry
Publication Date:
OSTI Identifier:
1188871
Report Number(s):
PNNL-SA--104452
Journal ID: ISSN 1076-5174; 48135; 47418; KP1601010
Grant/Contract Number:
AC05-76RL01830; CHE-1019193; DMR-11-57490; P41 GM103493
Type:
Accepted Manuscript
Journal Name:
Journal of Mass Spectrometry
Additional Journal Information:
Journal Volume: 50; Journal Issue: 1; Journal ID: ISSN 1076-5174
Publisher:
Wiley
Research Org:
Pacific Northwest National Laboratory (PNNL), Richland, WA (US), Environmental Molecular Sciences Laboratory (EMSL)
Sponsoring Org:
USDOE; National Science Foundation (NSF)
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION; 42 ENGINEERING FT MS; ICR; quadrupole ion guide; ion funnel; mass selection; Environmental Molecular Sciences Laboratory