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 The development of MP3 technologies illustrates the unexpected benefits of basic research. In 1965, a hand-sized storage and playback device that would hold 15,000 recorded songs was the stuff of science fiction. Even simple hand-held calculators were rare and expensive at that time.

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Godfrey Kneller's 1689 portrait of Isaac NewtonAs Isaac Newton said, "If I have seen further than others, it is by standing on...