Supercinski, Danielle
2006-01-01
stream_source_info A dash of salt.pdf.txt stream_content_type text/plain stream_size 9159 Content-Encoding ISO-8859-1 stream_name A dash of salt.pdf.txt Content-Type text/plain; charset=ISO-8859-1 tx H2O | pg. 18 A... Texas A&M researcher is assessing the impact of using moderately saline water for irrigating urban landscapes in West Texas and southern New Mexico. A DASH OF SALT Researcher assesses salinity impacts on grasses, trees and shrubs A Dash of Salt...
Quasielastic electron-deuteron scattering in the weak binding approximation
Ethier, Jacob J. [William and Mary College, JLAB; Doshi, Nidhi P. [Carnegie Mellon University; Malace, Simona P. [JLAB; Melnitchouk, Wally [JLAB
2014-06-01
We perform a global analysis of all available electron-deuteron quasielastic scattering data using Q^2-dependent smearing functions that describe inclusive inelastic e-d scattering within the weak binding approximation. We study the dependence of the cross sections on the deuteron wave function and the off-shell extrapolation of the elastic electron-nucleon cross section, which show particular sensitivity at x >> 1. The excellent overall agreement with data over a large range of Q^2 and x suggest a limited need for effects beyond the impulse approximation, with the exception of the very high-x or very low-Q^2 regions, where short-distance effects in the deuteron become more relevant.
Ferguson, Scarlett Blair
2012-10-19
Phosphofructokinase (PFK) from the lactic acid bacterium Lactobacillus delbrueckii subspecies bulgaricus (LbPFK) is a non-allosteric PFK with weak binding affinity for both the allosteric ligands phospho(enol)pyruvate (PEP) ...
Dash: Improving Community Repositories for Better Data Sharing
Strasser, Carly; Cruse, Patricia; Abrams, Stephen
2014-01-01
Tail of Science. Library Trends 57(2) Fall 2008. Dash:Preservation Program." Library Trends, 57:3 (2009): 301-314.
Bell, Geoffrey C.
2010-01-01
of Datacenter Automation Software and Hardware (DASH) at theof Datacenter Automation Software and Hardware (DASH) at theprotocol for building automation and control networks. It is
Dusanowski, ?.; Syperek, M. Rudno-Rudzi?ski, W.; Mrowi?ski, P.; Sek, G.; Misiewicz, J.; Somers, A.; Reithmaier, J. P.; Höfling, S.; Forchel, A.
2013-12-16
Exciton and biexciton dynamics in a single self-assembled InAs/In{sub 0.53}Ga{sub 0.23}Al{sub 0.24}As/InP(001) quantum dash emitting near 1.55??m has been investigated by micro-photoluminescence and time-resolved micro-photoluminescence at T?=?4.2?K. The exciton and biexciton fine structure splitting of ?60??eV, the biexciton binding energy of ?3.5?meV, and the characteristic exciton and biexciton decay times of 2.0?±?0.1?ns and 1.1?±?0.1?ns, respectively, have been determined. The measurement of the biexciton and exciton cross-correlation statistics of the photon emission confirmed the cascaded relaxation process. The exciton-to-biexciton decay time ratio and a small fine structure splitting suggest carrier localization within the investigated quantum dash.
Al-Hamdani, Yasmine S.; Alfè, Dario; von Lilienfeld, O. Anatole; Michaelides, Angelos
2014-10-22
Density functional theory (DFT) studies of weakly interacting complexes have recently focused on the importance of van der Waals dispersion forces, whereas the role of exchange has received far less attention. Here, by exploiting the subtle binding between water and a boron and nitrogen doped benzene derivative (1,2-azaborine) we show how exact exchange can alter the binding conformation within a complex. Benchmark values have been calculated for three orientations of the water monomer on 1,2-azaborine from explicitly correlated quantum chemical methods, and we have also used diffusion quantum Monte Carlo. For a host of popular DFT exchange-correlation functionals we show that the lack of exact exchange leads to the wrong lowest energy orientation of water on 1,2-azaborine. As such, we suggest that a high proportion of exact exchange and the associated improvement in the electronic structure could be needed for the accurate prediction of physisorption sites on doped surfaces and in complex organic molecules. Meanwhile to predict correct absolute interaction energies an accurate description of exchange needs to be augmented by dispersion inclusive functionals, and certain non-local van der Waals functionals (optB88- and optB86b-vdW) perform very well for absolute interaction energies. Through a comparison with water on benzene and borazine (B?N?H?) we show that these results could have implications for the interaction of water with doped graphene surfaces, and suggest a possible way of tuning the interaction energy.
Tensile GaAs(111) quantum dashes with tunable luminescence below the bulk bandgap
Yerino, Christopher D., E-mail: christopher.yerino@yale.edu; Jung, Daehwan; Lee, Minjoo Larry [Department of Electrical Engineering, Yale University, New Haven, Connecticut 06520 (United States); Simmonds, Paul J.; Liang, Baolai [California NanoSystems Institute, University of California, Los Angeles, California 90095 (United States); Dorogan, Vitaliy G.; Ware, Morgan E.; Mazur, Yuriy I.; Salamo, Gregory J. [Institute for Nanoscience and Engineering, University of Arkansas, Fayetteville, Arkansas 72701 (United States); Huffaker, Diana L. [California NanoSystems Institute, University of California, Los Angeles, California 90095 (United States); Department of Electrical Engineering, University of California, Los Angeles, California 90095 (United States)
2014-08-18
Strain-based band engineering in quantum dots and dashes has been predominantly limited to compressively strained systems. However, tensile strain strongly reduces the bandgaps of nanostructures, enabling nanostructures to emit light at lower energies than they could under compressive strain. We demonstrate the self-assembled growth of dislocation-free GaAs quantum dashes on an InP(111)B substrate, using a 3.8% tensile lattice-mismatch. Due to the high tensile strain, the GaAs quantum dashes luminesce at 110–240?meV below the bandgap of bulk GaAs. The emission energy is readily tuned by adjusting the size of the quantum dashes via deposition thickness. Tensile self-assembly creates new opportunities for engineering the band alignment, band structure, and optical properties of epitaxial nanostructures.
DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)
Al-Hamdani, Yasmine S.; Alfè, Dario; von Lilienfeld, O. Anatole; Michaelides, Angelos
2014-10-22
Density functional theory (DFT) studies of weakly interacting complexes have recently focused on the importance of van der Waals dispersion forces, whereas the role of exchange has received far less attention. Here, by exploiting the subtle binding between water and a boron and nitrogen doped benzene derivative (1,2-azaborine) we show how exact exchange can alter the binding conformation within a complex. Benchmark values have been calculated for three orientations of the water monomer on 1,2-azaborine from explicitly correlated quantum chemical methods, and we have also used diffusion quantum Monte Carlo. For a host of popular DFT exchange-correlation functionals we showmore »that the lack of exact exchange leads to the wrong lowest energy orientation of water on 1,2-azaborine. As such, we suggest that a high proportion of exact exchange and the associated improvement in the electronic structure could be needed for the accurate prediction of physisorption sites on doped surfaces and in complex organic molecules. Meanwhile to predict correct absolute interaction energies an accurate description of exchange needs to be augmented by dispersion inclusive functionals, and certain non-local van der Waals functionals (optB88- and optB86b-vdW) perform very well for absolute interaction energies. Through a comparison with water on benzene and borazine (B?N?H?) we show that these results could have implications for the interaction of water with doped graphene surfaces, and suggest a possible way of tuning the interaction energy.« less
Al-Hamdani, Yasmine S.; Michaelides, Angelos; Alfè, Dario; Lilienfeld, O. Anatole von
2014-11-14
Density functional theory (DFT) studies of weakly interacting complexes have recently focused on the importance of van der Waals dispersion forces, whereas the role of exchange has received far less attention. Here, by exploiting the subtle binding between water and a boron and nitrogen doped benzene derivative (1,2-azaborine) we show how exact exchange can alter the binding conformation within a complex. Benchmark values have been calculated for three orientations of the water monomer on 1,2-azaborine from explicitly correlated quantum chemical methods, and we have also used diffusion quantum Monte Carlo. For a host of popular DFT exchange-correlation functionals we show that the lack of exact exchange leads to the wrong lowest energy orientation of water on 1,2-azaborine. As such, we suggest that a high proportion of exact exchange and the associated improvement in the electronic structure could be needed for the accurate prediction of physisorption sites on doped surfaces and in complex organic molecules. Meanwhile to predict correct absolute interaction energies an accurate description of exchange needs to be augmented by dispersion inclusive functionals, and certain non-local van der Waals functionals (optB88- and optB86b-vdW) perform very well for absolute interaction energies. Through a comparison with water on benzene and borazine (B{sub 3}N{sub 3}H{sub 6}) we show that these results could have implications for the interaction of water with doped graphene surfaces, and suggest a possible way of tuning the interaction energy.
Optical injection modulation of quantum-dash semiconductor lasers by intra-cavity stimulated
.5960) Semiconductor lasers; (190.5650) Raman effect; (250.5590) quantum- well, -wire and -dot devices. References-temperature operation of InAs quantum-dash lasers on InP (001)," IEEE Photon. Technol. Lett. 13(8), 767769 (2001). 2. D. Loualiche, "Low-threshold current density InAs quantum dash lasers on InP (100) grown by molecular beam
Broadband emission in InAs/InGaAlAs quantum-dash-in-well laser Boon S. Ooi1, a
: Quantum dash, Quantum dot, Broadband emission, Semiconductor Laser. Abstract. We report on the developmentBroadband emission in InAs/InGaAlAs quantum-dash-in-well laser Boon S. Ooi1, a , Hery S. Djie1 of wide gain InAs/InGaAlAs/InP quantum-dash structure for broadband diode laser and amplifier
Single photon emission at 1.55??m from charged and neutral exciton confined in a single quantum dash
Dusanowski, ?. Syperek, M.; Mrowi?ski, P.; Rudno-Rudzi?ski, W.; Misiewicz, J.; S?k, G.; Somers, A.; Kamp, M.; Höfling, S.; Reithmaier, J. P.
2014-07-14
We investigate charged and neutral exciton complexes confined in a single self-assembled InAs/InGaAlAs/InP quantum dash emitting at 1.55??m. The emission characteristics have been probed by measuring high-spatial-resolution polarization-resolved photoluminescence and cross-correlations of photon emission statistics at T?=?5?K. The photon auto-correlation histogram of the emission from both the neutral and charged exciton indicates a clear antibunching dip with as-measured g{sup (2)}(0) values of 0.18 and 0.31, respectively. It proves that these exciton complexes confined in single quantum dashes of InP-based material system can act as true single photon emitters being compatible with standard long-distance fiber communication technology.
Weakly sufficient quantum statistics
Katarzyna Lubnauer; Andrzej ?uczak; Hanna Pods?dkowska
2009-11-23
Some aspects of weak sufficiency of quantum statistics are investigated. In particular, we give necessary and sufficient conditions for the existence of a weakly sufficient statistic for a given family of vector states, investigate the problem of its minimality, and find the relation between weak sufficiency and other notions of sufficiency employed so far.
Weak Interaction | Jefferson Lab
Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)
Weak Interaction February 22, 2011 Jefferson Lab has an accelerator designed to do incisive medium energy physics. This program is dominated by experiments aimed at developing our...
Galer, Meghan; Heiner, Jason
2014-01-01
Figure. Appearance of the patient’s affected right arm andnormal left arm. Volume XV, NO . 4 : July 2014 WesternI n E mergency M edicine Arm Weakness and Deformity Meghan
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DASH | Open Energy Information
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION J APPENDIX E LISTStar EnergyLawler,CoalConcordiaConsumerLEDSEnergy Information aka
Ultrastrong Optical Binding of Metallic Nanoparticles Vassili Demergis and Ernst-Ludwig Florin*
Texas at Austin. University of
Ultrastrong Optical Binding of Metallic Nanoparticles Vassili Demergis and Ernst-Ludwig Florin the optical binding force, which has been assumed to be weak compared to the optical gradient and scattering forces. We show that trapping by the optical binding force can be over 20 times stronger than
Emergent Soft Monopole Modes in Weakly-Bound Deformed Nuclei
J. C. Pei; M. Kortelainen; Y. N. Zhang; F. R. Xu
2014-11-13
Based on the Hartree-Fock-Bogoliubov solutions in large deformed coordinate spaces, the finite amplitude method for quasiparticle random phase approximation (FAM-QRPA) has been implemented, providing a suitable approach to probe collective excitations of weakly-bound nuclei embedded in the continuum. The monopole excitation modes in Magnesium isotopes up to the neutron drip line have been studied with the FAM-QRPA framework on both the coordinate-space and harmonic oscillator basis methods. Enhanced soft monopole strengths and collectivity as a result of weak-binding effects have been unambiguously demonstrated.
A Universe Without Weak Interactions
Harnik, Roni; Kribs, Graham D.; Perez, Gilad
2006-01-01
stars in the Weakless Universe begin fusion by the fastof obtaining a habitable universe. Acknowledgments We11795, hep-ph/0604027 A Universe Without Weak Interactions
Logistic regression Weakly informative priors
Gelman, Andrew
Logistic regression Weakly informative priors Conclusions Bayesian generalized linear models default p #12;Logistic regression Weakly informative priors Conclusions Classical logistic regression The problem of separation Bayesian solution Logistic regression -6 -4 -2 0 2 4 6 0.00.20.40.60.81.0 y = logit
Quantum Averages of Weak Values
Yakir Aharonov; Alonso Botero
2005-08-23
We re-examine the status of the weak value of a quantum mechanical observable as an objective physical concept, addressing its physical interpretation and general domain of applicability. We show that the weak value can be regarded as a \\emph{definite} mechanical effect on a measuring probe specifically designed to minimize the back-reaction on the measured system. We then present a new framework for general measurement conditions (where the back-reaction on the system may not be negligible) in which the measurement outcomes can still be interpreted as \\emph{quantum averages of weak values}. We show that in the classical limit, there is a direct correspondence between quantum averages of weak values and posterior expectation values of classical dynamical properties according to the classical inference framework.
Niemi, Sami-Matias; Cropper, Mark
2015-01-01
One of the most powerful techniques to study the dark sector of the Universe is weak gravitational lensing. In practice, to infer the reduced shear, weak lensing measures galaxy shapes, which are the consequence of both the intrinsic ellipticity of the sources and of the integrated gravitational lensing effect along the line of sight. Hence, a very large number of galaxies is required in order to average over their individual properties and to isolate the weak lensing cosmic shear signal. If this `shape noise' can be reduced, significant advances in the power of a weak lensing surveys can be expected. This paper describes a general method for extracting the probability distributions of parameters from catalogues of data using Voronoi cells, which has several applications, and has synergies with Bayesian hierarchical modelling approaches. This allows us to construct a probability distribution for the variance of the intrinsic ellipticity as a function of galaxy property using only photometric data, allowing a ...
Weak Deeply Virtual Compton Scattering
Ales Psaker; Wolodymyr Melnitchouk; Anatoly Radyushkin
2007-03-01
We extend the analysis of the deeply virtual Compton scattering process to the weak interaction sector in the generalized Bjorken limit. The virtual Compton scattering amplitudes for the weak neutral and charged currents are calculated at the leading twist within the framework of the nonlocal light-cone expansion via coordinate space QCD string operators. Using a simple model, we estimate cross sections for neutrino scattering off the nucleon, relevant for future high intensity neutrino beam facilities.
Weak-Chaos Ratchet Accelerator
Itzhack Dana; Vladislav B. Roitberg
2012-05-28
Classical Hamiltonian systems with a mixed phase space and some asymmetry may exhibit chaotic ratchet effects. The most significant such effect is a directed momentum current or acceleration. In known model systems, this effect may arise only for sufficiently strong chaos. In this paper, a Hamiltonian ratchet accelerator is introduced, featuring a momentum current for arbitrarily weak chaos. The system is a realistic, generalized kicked rotor and is exactly solvable to some extent, leading to analytical expressions for the momentum current. While this current arises also for relatively strong chaos, the maximal current is shown to occur, at least in one case, precisely in a limit of arbitrarily weak chaos.
Weak Values and Relational Generalisations
Thomas Marlow
2006-04-20
We justify generalisations of weak values from a tentatively relational perspective by deriving them from a generalisation of Bayes' rule. We also argue that these generalisations have implications of quantum nonlocality and may form a novel approach to quantum gravity and cosmology.
Dismantlability of weakly systolic complexes and applications
Chepoi, Victor
2009-01-01
In this paper, we investigate the structural properties of weakly systolic complexes introduced recently by the second author and of their 1-skeletons, the weakly bridged graphs. We present several characterizations of weakly systolic complexes and weakly bridged graphs. Then we prove that weakly bridged graphs are dismantlable. Using this, we establish the fixed point theorem for weakly systolic complexes. As a consequence, we get results about conjugacy classes of finite subgroups and classifying spaces for finite subgroups of weakly systolic groups. As immediate corollaries, we obtain new results on systolic complexes and systolic groups.
Weak values and weak coupling maximizing the output of weak measurements
Di Lorenzo, Antonio, E-mail: dilorenzo.antonio@gmail.com
2014-06-15
In a weak measurement, the average output ?o? of a probe that measures an observable A{sup -hat} of a quantum system undergoing both a preparation in a state ?{sub i} and a postselection in a state E{sub f} is, to a good approximation, a function of the weak value A{sub w}=Tr[E{sub f}A{sup -hat} ?{sub i}]/Tr[E{sub f}?{sub i}], a complex number. For a fixed coupling ?, when the overlap Tr[E{sub f}?{sub i}] is very small, A{sub w} diverges, but ?o? stays finite, often tending to zero for symmetry reasons. This paper answers the questions: what is the weak value that maximizes the output for a fixed coupling? What is the coupling that maximizes the output for a fixed weak value? We derive equations for the optimal values of A{sub w} and ?, and provide the solutions. The results are independent of the dimensionality of the system, and they apply to a probe having a Hilbert space of arbitrary dimension. Using the Schrödinger–Robertson uncertainty relation, we demonstrate that, in an important case, the amplification ?o? cannot exceed the initial uncertainty ?{sub o} in the observable o{sup -hat}, we provide an upper limit for the more general case, and a strategy to obtain ?o???{sub o}. - Highlights: •We have provided a general framework to find the extremal values of a weak measurement. •We have derived the location of the extremal values in terms of preparation and postselection. •We have devised a maximization strategy going beyond the limit of the Schrödinger–Robertson relation.
Grossman, Jeffrey C.
We analyze the density-functional theory (DFT) description of weak interactions by employing diffusion and reptation quantum Monte Carlo (QMC) calculations, for a set of benzene-molecule complexes. While the binding energies ...
Global Superdiffusion of Weak Chaos
Itzhack Dana
2003-10-20
A class of kicked rotors is introduced, exhibiting accelerator-mode islands (AIs) and {\\em global} superdiffusion for {\\em arbitrarily weak} chaos. The corresponding standard maps are shown to be exactly related to generalized web maps taken modulo an ``oblique cylinder''. Then, in a case that the web-map orbit structure is periodic in the phase plane, the AIs are essentially {\\em normal} web islands folded back into the cylinder. As a consequence, chaotic orbits sticking around the AI boundary are accelerated {\\em only} when they traverse tiny {\\em ``acceleration spots''}. This leads to chaotic flights having a quasiregular {\\em steplike} structure. The global weak-chaos superdiffusion is thus basically different in nature from the strong-chaos one in the usual standard and web maps.
Probing the Proton's Weak Side | Jefferson Lab
Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)
force. The weak force acts on subatomic particles, such as the protons, neutrons and electrons that make up atoms. These particles carry a weak charge, a measure of the influence...
Chanowitz, M.S.
1986-03-01
Prospects for the study of standard model weak interactions at the SSC are reviewed, with emphasis on the unique capability of the SSC to study the mechanism of electroweak symmetry breaking whether the associated new quanta are at the TeV scale or higher. Symmetry breaking by the minimal Higgs mechanism and by related strong interaction dynamical variants is summarized. A set of measurements is outlined that would calibrate the proton structure functions and the backgrounds to new physics. The ability to measure the three weak gauge boson vertex is found to complement LEP II, with measurements extending to larger Q/sup 2/ at a comparable statistical level in detectable decays. B factory physics is briefly reviewed as one example of a possible broad program of high statistics studies of sub-TeV scale phenomena. The largest section of the talk is devoted to the possible manifestations of symmetry breaking in the WW and ZZ production cross sections. Some new results are presented bearing on the ability to detect high mass WW and ZZ pairs. The principal conclusion is that although nonstandard model scenarios are typically more forgiving, the capability to study symmetry breaking in the standard model (and in related strong interaction dynamical variants) requires achieving the SSC design goals of ..sqrt.. s,L = 40Tev, 10/sup 33/cm/sup -2/sec/sup -1/. 28 refs., 5 figs.
Cellulose binding domain proteins
Shoseyov, Oded (Karmey Yosef, IL); Shpiegl, Itai (Rehovot, IL); Goldstein, Marc (Davis, CA); Doi, Roy (Davis, CA)
1998-01-01
A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production thereof. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques.
Cellulose binding domain proteins
Shoseyov, O.; Shpiegl, I.; Goldstein, M.; Doi, R.
1998-11-17
A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques. 16 figs.
Structural and Histone Binding Ability Characterizations of Human PWWP Domains
Wu, Hong; Zeng, Hong; Lam, Robert; Tempel, Wolfram; Amaya, Maria F.; Xu, Chao; Dombrovski, Ludmila; Qiu, Wei; Wang, Yanming; Min, Jinrong (Toronto); (Penn)
2013-09-25
The PWWP domain was first identified as a structural motif of 100-130 amino acids in the WHSC1 protein and predicted to be a protein-protein interaction domain. It belongs to the Tudor domain 'Royal Family', which consists of Tudor, chromodomain, MBT and PWWP domains. While Tudor, chromodomain and MBT domains have long been known to bind methylated histones, PWWP was shown to exhibit histone binding ability only until recently. The PWWP domain has been shown to be a DNA binding domain, but sequence analysis and previous structural studies show that the PWWP domain exhibits significant similarity to other 'Royal Family' members, implying that the PWWP domain has the potential to bind histones. In order to further explore the function of the PWWP domain, we used the protein family approach to determine the crystal structures of the PWWP domains from seven different human proteins. Our fluorescence polarization binding studies show that PWWP domains have weak histone binding ability, which is also confirmed by our NMR titration experiments. Furthermore, we determined the crystal structures of the BRPF1 PWWP domain in complex with H3K36me3, and HDGF2 PWWP domain in complex with H3K79me3 and H4K20me3. PWWP proteins constitute a new family of methyl lysine histone binders. The PWWP domain consists of three motifs: a canonical {beta}-barrel core, an insertion motif between the second and third {beta}-strands and a C-terminal {alpha}-helix bundle. Both the canonical {beta}-barrel core and the insertion motif are directly involved in histone binding. The PWWP domain has been previously shown to be a DNA binding domain. Therefore, the PWWP domain exhibits dual functions: binding both DNA and methyllysine histones.
Maximal Holevo quantity based on weak measurements
Yao-Kun Wang; Shao-Ming Fei; Zhi-Xi Wang; Jun-Peng Cao; Heng Fan
2015-01-13
The Holevo bound is a keystone in many applications of quantum information theory. We propose "weak maximal Holevo quantity" with weak measurements as the generalization of the standard Holevo quantity which is defined as the optimal projective measurements. The scenarios that weak measurements is necessary are that only the weak measurements can be performed because for example the system is macroscopic or that one intentionally tries to do so such that the disturbance on the measured system can be controlled for example in quantum key distribution protocols. We evaluate systematically the weak maximal Holevo quantity for Bell-diagonal states and find a series of results. Furthermore, we find that weak measurements can be realized by noise and project measurements.
Weak measurement and control of entanglement generation
Charles D. Hill; J. F. Ralph
2008-01-28
In this paper we show how weak joint measurement and local feedback can be used to control entanglement generation between two qubits. To do this, we make use of a decoherence free subspace (DFS). Weak measurement and feedback can be used to drive the system into this subspace rapidly. Once within the subspace, feedback can generate entanglement rapidly, or turn off entanglement generation dynamically. We also consider, in the context of weak measurement, some of differences between purification and generating entanglement.
Low-energy Electro-weak Reactions
Doron Gazit
2012-10-16
Chiral effective field theory (EFT) provides a systematic and controlled approach to low-energy nuclear physics. Here, we use chiral EFT to calculate low-energy weak Gamow-Teller transitions. We put special emphasis on the role of two-body (2b) weak currents within the nucleus, and discuss their applications in predicting physical observables.
Weak rigidity in the PPN formalism
del Olmo, V.; Olivert, J.
1987-04-01
The influence of the concept of weakly rigid almost-thermodynamic material schemes on the classical deformations is analyzed. The methods of the PPN approximation are considered. In this formalism, the equations that characterize the weak rigidity are expressed. As a consequence of that, an increase of two orders of magnitude in the strain rate tensor is obtained.
Weak measurement based on thermal noise effect
Gang Li; Tao Wang; Shuang Xu; He-Shan Song
2015-07-03
Weak measurement with thermal state pointer can give rise to an amplification effect, and we give the generalization of the mechanism behind the amplification with pure Gaussion state pointer. We find that the maximal value of this effect can reach thermal fluctuations, and propose two schemes to implement room temperature weak measurement with thermal state pointer in optomechanical system.
SEEING AND COMMUNICATING THROUGH WEAK ELECTRIC
their lives bathed in their own internally generated mild electric field, interpreting perturbations. But in the case of electric field generation, the signals are easy to record, analyse and mimic, and you canInside JEB i SEEING AND COMMUNICATING THROUGH WEAK ELECTRIC FIELDS Weakly electric fish spend
Quantum correlation cost of the weak measurement
Jun Zhang; Shao-xiong Wu; Chang-shui Yu
2014-09-14
Quantum correlation cost (QCC) characterizing how much quantum correlation is used in a weak-measurement process is presented based on the trace norm. It is shown that the QCC is related to the trace-norm-based quantum discord (TQD) by only a factor that is determined by the strength of the weak measurement, so it only catches partial quantumness of a quantum system compared with the TQD. We also find that the residual quantumness can be `extracted' not only by the further von Neumann measurement, but also by a sequence of infinitesimal weak measurements. As an example, we demonstrate our outcomes by the Bell-diagonal state.
MANAGING TIGHT BINDING RECEPTORS FOR NEW SPEARATIONS TECHNOLOGIES
DARYLE H BUSCH RICHARD S GIVENS
2004-12-10
Much of the earth's pollution involves compounds of the metallic elements, including actinides, strontium, cesium, technetium, and RCRA metals. Metal ions bind to molecules called ligands, which are the molecular tools that can manipulate the metal ions under most conditions. This DOE-EMSP sponsored program strives (1) to provide the foundations for using the most powerful ligands in transformational separations technologies and (2) to produce seminal examples of their applications to separations appropriate to the DOE EM mission. These ultra tight-binding ligands can capture metal ions in the most competitive of circumstances (from mineralized sites, lesser ligands, and even extremely dilute solutions), but they react so slowly that they are useless in traditional separations methodologies. Two attacks on this problem are underway. The first accommodates to the challenging molecular lethargy by developing a seminal slow separations methodology termed the soil poultice. The second designs ligands that are only tight-binding while wrapped around the targeted metal ion, but can be put in place by switch-binding and removed by switch-release. We envision a kind of molecular switching process to accelerate the union between metal ion and tight-binding ligand. Molecular switching processes are suggested for overcoming the slow natural equilibration rate with which ultra tight-binding ligands combine with metal ions. Ligands that bind relatively weakly combine with metal ions rapidly, so the trick is to convert a ligand from a weak, rapidly binding species to a powerful, slow releasing ligand--during the binding of the ligand to the metal ion. Such switch-binding ligands must react with themselves, and the reaction must take place under the influence of the metal ion. For example, our generation 1 ligands showed that a well-designed linear ligand with ends that readily combine, forms a cyclic molecule when it wraps around a metal ion. Our generation 2 ligands are even more interesting. They convert from rings to structures that wrap around a metal ion to form a cage. These ligands are called cryptands. Switch release is accomplished by photolytic cleavage of a bond to convert a cyclic ligand into a linear ligand or to break similar bonds in a cryptate. Our studies have demonstrated switch binding and switch release with cryptates of calcium. These remarkable cyclic ligands and cage-like ligands are indeed tight-binding and may, in principle, be incorporated in various separations methodologies, including the soil poultice. The soil poultice mimics the way in which microbes secrete extremely powerful ligands into the soil in order to harvest iron. The cellular membrane of the microbe recognizes the iron/ligand complex and admits it into the cell. The soil poultice uses molecularly imprinted polymers (MIPs) to play the role of the cellular membrane. Imprinting involves creation of the polymer in the presence of the metal/ligand complex. In principle, a well design ligand/MIP combination can be highly selective toward almost any targeted metal ion. The principles for that design are the focus of these investigations. An imprinting molecule can interact with the polymer through any, some, or all of the so-called supramolecular modes; e.g., hydrogen bonding, electrostatic charge, minor ligand bonding, Pi-Pi stacking, and hydrophobic and van der Waals interactions. Historically these modes of binding have given MIPs only small re-binding capacities and very limited selectivities. This program has shown that each mode of interaction can be made more powerful than previously suspected and that combinations of different supramolecular interaction modes can produce remarkable synergisms. The results of this systematic study provide a firm foundation for tailoring molecular imprinted polymers for reclamation of specific metal ion, including those important to the DOE EM mission.
Weak Lensing Simulations for the SKA
Patel, Prina; Makhathini, Sphesihle; Abdalla, Filipe; Bacon, David; Brown, Michael L; Heywood, Ian; Jarvis, Matt; Smirnov, Oleg
2015-01-01
Weak gravitational lensing measurements are traditionally made at optical wavelengths where many highly resolved galaxy images are readily available. However, the Square Kilometre Array (SKA) holds great promise for this type of measurement at radio wavelengths owing to its greatly increased sensitivity and resolution over typical radio surveys. The key to successful weak lensing experiments is in measuring the shapes of detected sources to high accuracy. In this document we describe a simulation pipeline designed to simulate radio images of the quality required for weak lensing, and will be typical of SKA observations. We provide as input, images with realistic galaxy shapes which are then simulated to produce images as they would have been observed with a given radio interferometer. We exploit this pipeline to investigate various stages of a weak lensing experiment in order to better understand the effects that may impact shape measurement. We first show how the proposed SKA1-Mid array configurations perfor...
WEAK APPROXIMATION OF FRACTIONAL SDES: THE DONSKER ...
2010-07-23
Jun 6, 2010 ... introduction. Indeed, in the latter reference, the .... Electronic Communications in Probability .... structure of weakly controlled process introduced in [10]. ...... [13] T. Lyons and Z. Qian (2002): System control and rough paths.
Can the trace formula describe weak localisation?
Robert S. Whitney; Igor V. Lerner; Robert A. Smith
1999-02-24
We attempt to systematically derive perturbative quantum corrections to the Berry diagonal approximation of the two-level correlation function (TLCF) for chaotic systems. To this end, we develop a ``weak diagonal approximation'' based on a recent description of the first weak localisation correction to conductance in terms of the Gutzwiller trace formula. This semiclassical method is tested by using it to derive the weak localisation corrections to the TLCF for a semiclassically disordered system. Unfortunately the method is unable to correctly reproduce the ``Hikami boxes'' (the relatively small regions where classical paths are glued together by quantum processes). This results in the method failing to reproduce the well known weak localisation expansion. It so happens that for the first order correction it merely produces the wrong prefactor. However for the second order correction, it is unable to reproduce certain contributions, and leads to a result which is of a different form to the standard one.
Uncertainty and Complementarity Relations in Weak Measurement
Arun Kumar Pati; Junde Wu
2014-11-26
We prove uncertainty relations that quantitatively express the impossibility of jointly sharp preparation of pre- and post-selected quantum states for measuring incompatible observables during the weak measurement. By defining a suitable operator whose average in the pre-selected quantum state gives the weak value, we show that one can have new uncertainty relations for variances of two such operators corresponding to two non-commuting observables. These generalize the recent stronger uncertainty relations that give non-trivial lower bounds for the sum of variances of two observables which fully capture the concept of incompatible observables. Furthermore, we show that weak values for two non-commuting projection operators obey a complementarity relation. Specifically, we show that for a pre-selected state if we measure a projector corresponding to an observable $A$ weakly followed by the strong measurement of another observable $B$ (for the post-selection) and, for the same pre-selected state we measure a projector corresponding to an observable $B$ weakly followed by the strong measurement of the observable $A$ (for the post-selection), then the product of these two weak values is always less than one. This shows that even though individually they are complex and can be large, their product is always bounded.
Q-weak Experiment Determines Proton's Weak Charge | U.S. DOE...
Office of Science (SC) Website
of how the universe works-postulates that there are only four fundamental forces: electromagnetism, gravity, the "strong" force, and the "weak" force. The latter two are...
Origins of weak lensing systematics, and requirements on future...
Office of Scientific and Technical Information (OSTI)
Origins of weak lensing systematics, and requirements on future instrumentation (or knowledge of instrumentation) Citation Details In-Document Search Title: Origins of weak lensing...
Theory and Modeling of Weakly Bound/Physisorbed Materials for...
Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site
Theory and Modeling of Weakly BoundPhysisorbed Materials for Hydrogen Storage Theory and Modeling of Weakly BoundPhysisorbed Materials for Hydrogen Storage Presentation on the...
Gunasekara, Nirosha [Department of Laboratory Medicine and Pathology, University of Alberta, 5B4.21 WCM Health Science Centre, 8440-112th Street, Edmonton, Alberta, Canada T6G 2R7 (Canada)] [Department of Laboratory Medicine and Pathology, University of Alberta, 5B4.21 WCM Health Science Centre, 8440-112th Street, Edmonton, Alberta, Canada T6G 2R7 (Canada); Sykes, Brian, E-mail: brian.sykes@ualberta.ca [Department of Biochemistry, 4-19B Medical Sciences Bldg., University of Alberta Edmonton, Alberta, Canada T6G 2H7 (Canada)] [Department of Biochemistry, 4-19B Medical Sciences Bldg., University of Alberta Edmonton, Alberta, Canada T6G 2H7 (Canada); Hugh, Judith, E-mail: judithh@ualberta.ca [Department of Laboratory Medicine and Pathology, University of Alberta, 5B4.21 WCM Health Science Centre, 8440-112th Street, Edmonton, Alberta, Canada T6G 2R7 (Canada)] [Department of Laboratory Medicine and Pathology, University of Alberta, 5B4.21 WCM Health Science Centre, 8440-112th Street, Edmonton, Alberta, Canada T6G 2R7 (Canada)
2012-05-18
Highlights: Black-Right-Pointing-Pointer MUC1 binds the Src-SH3 domain potentially triggering Src dependent cell migration. Black-Right-Pointing-Pointer NMR Spectroscopy was used to monitor MUC1-CD and Src SH3 domain titrations. Black-Right-Pointing-Pointer MUC1-CD peptides bind with a low affinity (K{sub d} of 2-3 mM) to a non-canonical site. Black-Right-Pointing-Pointer Weak interactions may mediate dynamic processes like migration. Black-Right-Pointing-Pointer The MUC1-CD and Src-SH3 interaction may be a prime target to inhibit cell migration. -- Abstract: Breast cancer causes death through cancer cell migration and subsequent metastasis to distant organs. In vitro, the MUC1 mucin can mediate breast cancer cell migration by binding to intercellular adhesion molecule-1 (ICAM-1). This migration is dependent on MUC1 cytoplasmic domain (MUC1-CD) activation of the non-receptor tyrosine kinase, Src, possibly through competitive displacement of an inhibitory Src intramolecular SH3 binding. Therefore, we characterized the binding site and affinity of the MUC1-CD for Src-SH3 using multidimensional nuclear magnetic resonance (NMR) spectroscopy to monitor the titration of the {sup 15}N labeled Src-SH3 domain with synthetic native and mutant peptides of MUC1-CD. The results revealed that the dissociation constant (K{sub d}) for the interaction of the native MUC1-CD peptides and Src-SH3 domain was weak with a K{sub d} of 2-3 mM. Notably, the SH3 residues most perturbed upon peptide binding were located outside the usual hydrophobic binding cleft in a previously described alternate binding site on the Src-SH3, suggesting that MUC1-CD binds to a non-canonical site. The binding characteristics outlined here suggest that the interaction between Src-SH3 and MUC1-CD represents a novel weak electrostatic interaction of the type which is increasingly recognized as important in transient and dynamic protein complexes required for cell migration and signal transduction. As such, this study forms the foundation for the design of specific inhibitors of this interaction which may target breast cancer metastases with exquisite specificity.
Quantum Communication Protocol Employing Weak Measurements
Alonso Botero; Benni Reznik
1999-09-27
We propose a communication protocol exploiting correlations between two events with a definite time-ordering: a) the outcome of a {\\em weak measurement} on a spin, and b) the outcome of a subsequent ordinary measurement on the spin. In our protocol, Alice, first generates a "code" by performing weak measurements on a sample of N spins. The sample is sent to Bob, who later performs a post-selection by measuring the spin along either of two certain directions. The results of the post-selection define the "key', which he then broadcasts publicly. Using both her previously generated code and this key, Alice is able to infer the {\\em direction} chosen by Bob in the post-selection. Alternatively, if Alice broadcasts publicly her code, Bob is able to infer from the code and the key the direction chosen by Alice for her weak measurement. Two possible experimental realizations of the protocols are briefly mentioned.
Strong effects in weak nonleptonic decays
Wise, M.B.
1980-04-01
In this report the weak nonleptonic decays of kaons and hyperons are examined with the hope of gaining insight into a recently proposed mechanism for the ..delta..I = 1/2 rule. The effective Hamiltonian for ..delta..S = 1 weak nonleptonic decays and that for K/sup 0/-anti K/sup 0/ mixing are calculated in the six-quark model using the leading logarithmic approximation. These are used to examine the CP violation parameters of the kaon system. It is found that if Penguin-type diagrams make important contributions to K ..-->.. ..pi pi.. decay amplitudes then upcoming experiments may be able to distinguish the six-quark model for CP violation from the superweak model. The weak radiative decays of hyperons are discussed with an emphasis on what they can teach us about hyperon nonleptonic decays and the ..delta..I = 1/2 rule.
Kirby, James T.
Formation of Hydro-acoustic Waves in Weakly Compressible Fluid Interacting with Viscous Weakly@udel.edu, giorgio.bellotti@uniroma3.it 1. Objective Enhancement of Tsunami Early Warning Systems (TEWS) Hydro/s) [2]. Study of the characteristics of hydro-acoustic waves generated by sudden sea bottom motion
Weak Lensing: Dark Matter, Dark Energy
Jain, Bhuvnesh (University of Pennsylvania) [University of Pennsylvania
2006-02-27
The light rays from distant galaxies are deflected by massive structures along the line of sight, causing the galaxy images to be distorted. Measurements of these distortions, known as weak lensing, provide a way of measuring the distribution of dark matter as well as the spatial geometry of the universe. I will describe the ideas underlying this approach to cosmology. With planned large imaging surveys, weak lensing is a powerful probe of dark energy. I will discuss the observational challenges ahead and recent progress in developing multiple, complementary approaches to lensing measurements.
Nuclear weak interaction rates in primordial nucleosynthesis
George M. Fuller; Christel J. Smith
2010-09-01
We calculate the weak interaction rates of selected light nuclei during the epoch of Big Bang Nucleosynthesis (BBN), and we assess the impact of these rates on nuclear abundance flow histories and on final light element abundance yields. We consider electron and electron antineutrino captures on 3He and 7Be, and the reverse processes of positron capture and electron neutrino capture on 3H and 7Li. We also compute the rates of positron and electron neutrino capture on 6He. We calculate beta and positron decay transitions where appropriate. As expected, the final standard BBN abundance yields are little affected by addition of these weak processes, though there can be slight alterations of nuclear flow histories. However, non-standard BBN scenarios, e.g., those involving out of equilibrium particle decay with energetic final state neutrinos, may be affected by these processes.
The strict-weak lattice polymer
Ivan Corwin; Timo Seppäläinen; Hao Shen
2015-07-06
We introduce the strict-weak polymer model, and show the KPZ universality of the free energy fluctuation of this model for a certain range of parameters. Our proof relies on the observation that the discrete time geometric q-TASEP model, studied earlier by A. Borodin and I. Corwin, scales to this polymer model in the limit q->1. This allows us to exploit the exact results for geometric q-TASEP to derive a Fredholm determinant formula for the strict-weak polymer, and in turn perform rigorous asymptotic analysis to show KPZ scaling and GUE Tracy-Widom limit for the free energy fluctuations. We also derive moments formulae for the polymer partition function directly by Bethe ansatz, and identify the limit of the free energy using a stationary version of the polymer model.
Weakly nonlocal fluid mechanics - the Schrodinger equation
P. Van; T. Fulop
2004-06-09
A weakly nonlocal extension of ideal fluid dynamics is derived from the Second Law of thermodynamics. It is proved that in the reversible limit the additional pressure term can be derived from a potential. The requirement of the additivity of the specific entropy function determines the quantum potential uniquely. The relation to other known derivations of Schr\\"odinger equation (stochastic, Fisher information, exact uncertainty) is clarified.
Novel Weak Decays in Doubly Strange Systems
A. Parreno; A. Ramos; C. Bennhold
2001-06-22
The strangeness-changing ($\\Delta S = 1$) weak baryon-baryon interaction is studied through the nonmesonic weak decay of double-$\\Lambda$ hypernuclei. Besides the usual nucleon-induced decay $\\Lambda N \\to N N$ we discuss novel hyperon-induced decay modes $\\Lambda \\Lambda \\to \\Lambda N$ and $\\Lambda \\Lambda \\to \\Sigma N$. These reactions provide unique access to the exotic $\\Lambda \\Lambda$K and $\\Lambda \\Sigma$K vertices which place new constraints on Chiral Pertubation Theory ($\\chi$PT) in the weak SU(3) sector. Within a meson-exchange framework, we use the pseudoscalar $\\pi,\\eta,K$ octet for the long-range part while parametrizing the short-range part through the vector mesons $\\rho, \\omega, K^*$. Realistic baryon-baryon forces for the $S=0,-1$ and -2 sectors account for the strong interaction in the initial and final states. For $^6_{\\Lambda \\Lambda}$He the new hyperon-induced decay modes account for up to 4% of the total nonmesonic decay rate. Predictions are made for all possible nonmesonic decay modes.
Weak measurement and Bohmian conditional wave functions
Norsen, Travis; Struyve, Ward
2014-11-15
It was recently pointed out and demonstrated experimentally by Lundeen et al. that the wave function of a particle (more precisely, the wave function possessed by each member of an ensemble of identically-prepared particles) can be “directly measured” using weak measurement. Here it is shown that if this same technique is applied, with appropriate post-selection, to one particle from a perhaps entangled multi-particle system, the result is precisely the so-called “conditional wave function” of Bohmian mechanics. Thus, a plausibly operationalist method for defining the wave function of a quantum mechanical sub-system corresponds to the natural definition of a sub-system wave function which Bohmian mechanics uniquely makes possible. Similarly, a weak-measurement-based procedure for directly measuring a sub-system’s density matrix should yield, under appropriate circumstances, the Bohmian “conditional density matrix” as opposed to the standard reduced density matrix. Experimental arrangements to demonstrate this behavior–and also thereby reveal the non-local dependence of sub-system state functions on distant interventions–are suggested and discussed. - Highlights: • We study a “direct measurement” protocol for wave functions and density matrices. • Weakly measured states of entangled particles correspond to Bohmian conditional states. • Novel method of observing quantum non-locality is proposed.
Synthetic heparin-binding growth factor analogs
Pena, Louis A.; Zamora, Paul; Lin, Xinhua; Glass, John D.
2007-01-23
The invention provides synthetic heparin-binding growth factor analogs having at least one peptide chain that binds a heparin-binding growth factor receptor, covalently bound to a hydrophobic linker, which is in turn covalently bound to a non-signaling peptide that includes a heparin-binding domain. The synthetic heparin-binding growth factor analogs are useful as soluble biologics or as surface coatings for medical devices.
Mad Dash Inc | Open Energy Information
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION J APPENDIXsource HistoryScenarios Towards 2050EnermarGeneration Jump to: navigation, search
A comparison of weak-turbulence and PIC simulations of weak electron-beam plasma interaction
Ratcliffe, Heather; Rozenan, Mohammed B Che; Nakariakov, Valery
2014-01-01
Quasilinear theory has long been used to treat the problem of a weak electron beam interacting with plasma and generating Langmuir waves. Its extension to weak-turbulence theory treats resonant interactions of these Langmuir waves with other plasma wave modes, in particular ion-sound waves. These are strongly damped in plasma of equal ion and electron temperatures, as sometimes seen in, for example, the solar corona and wind. Weak turbulence theory is derived in the weak damping limit, with a term describing ion-sound wave damping then added. In this paper we use the EPOCH particle-in-cell code to numerically test weak turbulence theory for a range of electron-ion temperature ratios. We find that in the cold ion limit the results agree well, but increasing ion temperature the three-wave resonance becomes broadened in proportion to the ion-sound wave damping rate. This may be important in, for example, the theory of solar radio bursts, where the spectrum of Langmuir waves is critical. Additionally we establish...
Lossy compression of weak lensing data
DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)
Vanderveld, R. Ali; Bernstein, Gary M.; Stoughton, Chris; Rhodes, Jason; Massey, Richard; Dobke, Benjamin M.
2011-07-12
Future orbiting observatories will survey large areas of sky in order to constrain the physics of dark matter and dark energy using weak gravitational lensing and other methods. Lossy compression of the resultant data will improve the cost and feasibility of transmitting the images through the space communication network. We evaluate the consequences of the lossy compression algorithm of Bernstein et al. (2010) for the high-precision measurement of weak-lensing galaxy ellipticities. This square-root algorithm compresses each pixel independently, and the information discarded is by construction less than the Poisson error from photon shot noise. For simulated space-based images (without cosmicmore »rays) digitized to the typical 16 bits per pixel, application of the lossy compression followed by image-wise lossless compression yields images with only 2.4 bits per pixel, a factor of 6.7 compression. We demonstrate that this compression introduces no bias in the sky background. The compression introduces a small amount of additional digitization noise to the images, and we demonstrate a corresponding small increase in ellipticity measurement noise. The ellipticity measurement method is biased by the addition of noise, so the additional digitization noise is expected to induce a multiplicative bias on the galaxies measured ellipticities. After correcting for this known noise-induced bias, we find a residual multiplicative ellipticity bias of m {approx} -4 x 10-4. This bias is small when compared to the many other issues that precision weak lensing surveys must confront, and furthermore we expect it to be reduced further with better calibration of ellipticity measurement methods.« less
HISTORY OF WEAK INTERACTIONS. | SciTech Connect
Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)
HISTORY OF WEAK INTERACTIONS. Citation Details In-Document Search Title: HISTORY OF WEAK INTERACTIONS. You are accessing a document from the Department of Energy's (DOE) SciTech...
Contradiction and grammar : the case of weak islands
Abrusán, Márta
2007-01-01
This thesis is about weak islands. Weak islands are contexts that are transparent to some but not all operator-variable dependencies. For this reason, they are also sometimes called selective islands. Some paradigmatic ...
Wave turbulent statistics in non-weak wave turbulence
Naoto Yokoyama
2011-05-08
In wave turbulence, it has been believed that statistical properties are well described by the weak turbulence theory, in which nonlinear interactions among wavenumbers are assumed to be small. In the weak turbulence theory, separation of linear and nonlinear time scales derived from the weak nonlinearity is also assumed. However, the separation of the time scales is often violated even in weak turbulent systems where the nonlinear interactions are actually weak. To get rid of this inconsistency, closed equations are derived without assuming the separation of the time scales in accordance with Direct-Interaction Approximation (DIA), which has been successfully applied to Navier--Stokes turbulence. The kinetic equation of the weak turbulence theory is recovered from the DIA equations if the weak nonlinearity is assumed as an additional assumption. It suggests that the DIA equations is a natural extension of the conventional kinetic equation to not-necessarily-weak wave turbulence.
Weak crystallization theory of metallic alloys
Ivar Martin; Sarang Gopalakrishnan; Eugene A. Demler
2015-06-09
We extend the Weak Crystallization theory to the case of metallic alloys. The additional ingredient -- itinerant electrons -- generates nontrivial dependence of free energy on the angles between ordering wave vectors of ionic density. That leads to stabilization of FCC, Rhombohedral, and icosahedral quasicrystalline (iQC) phases, which are absent in the generic theory with only local interactions. The condition for stability of iQC that we find, is consistent with the Hume-Rothery rules known empirically for majority of stable iQC; namely, the length of the primary Bragg peak wavevector is approximately equal to the diameter of the Fermi surface.
Thermodynamics of weakly measured quantum systems
Jose Joaquin Alonso; Eric Lutz; Alessandro Romito
2015-08-03
We consider continuously monitored quantum systems and introduce definitions of work and heat along individual quantum trajectories that are valid for coherent superpositions of energy eigenstates. We use these quantities to extend the first and second laws of stochastic thermodynamics to the quantum domain. We illustrate our results with the case of a weakly measured driven two-level system and show how to distinguish between quantum work and heat contributions. We finally employ quantum feedback control to suppress detector backaction and determine the work statistics.
PLASMA EMISSION BY WEAK TURBULENCE PROCESSES
Ziebell, L. F.; Gaelzer, R.; Yoon, P. H.; Pavan, J. E-mail: rudi.gaelzer@ufrgs.br E-mail: joel.pavan@ufpel.edu.br
2014-11-10
The plasma emission is the radiation mechanism responsible for solar type II and type III radio bursts. The first theory of plasma emission was put forth in the 1950s, but the rigorous demonstration of the process based upon first principles had been lacking. The present Letter reports the first complete numerical solution of electromagnetic weak turbulence equations. It is shown that the fundamental emission is dominant and unless the beam speed is substantially higher than the electron thermal speed, the harmonic emission is not likely to be generated. The present findings may be useful for validating reduced models and for interpreting particle-in-cell simulations.
Supersymmetric Higgs Bosons in Weak Boson Fusion
W. Hollik; T. Plehn; M. Rauch; H. Rzehak
2008-04-17
We compute the complete supersymmetric next-to-leading order corrections to the production of a light Higgs boson in weak boson fusion. The size of the electroweak corrections is of similar order as the next-to-leading order corrections in the Standard Model. The supersymmetric QCD corrections turn out to be significantly smaller than their electroweak counterparts. These higher--order corrections are an important ingredient to a precision analysis of the (supersymmetric) Higgs sector at the LHC, either as a known correction factor or as a contribution to the theory error.
Boson Hubbard model with weakly coupled fermions
Lutchyn, Roman M.; Tewari, Sumanta; Das Sarma, S.
2008-12-01
Using an imaginary-time path integral approach, we develop the perturbation theory suited to the boson Hubbard model and apply it to calculate the effects of a dilute gas of spin-polarized fermions weakly interacting with the bosons. The full theory captures both the static and the dynamic effects of the fermions on the generic superfluid-insulator phase diagram. We find that, in a homogenous system described by a single-band boson Hubbard Hamiltonian, the intrinsic perturbative effect of the fermions is to generically suppress the insulating lobes and to enhance the superfluid phase.
Cellulose binding domain fusion proteins
Shoseyov, O.; Yosef, K.; Shpiegl, I.; Goldstein, M.A.; Doi, R.H.
1998-02-17
A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques. 16 figs.
Cellulose binding domain fusion proteins
Shoseyov, Oded (Karmey Yosef, IL); Shpiegl, Itai (Rehovot, IL); Goldstein, Marc A. (Davis, CA); Doi, Roy H. (Davis, CA)
1998-01-01
A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production thereof. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques.
Geometric control theory, closing lemma, and weak KAM theory
Rifford, Ludovic
Geometric control theory, closing lemma, and weak KAM theory Ludovic Rifford UniversitÂ´e de Nice - Sophia Antipolis Ludovic Rifford Weak KAM Theory in Italy #12;Outline Lecture 1: Geometric control) Lecture 4: Closing Aubry sets Ludovic Rifford Weak KAM Theory in Italy #12;Lecture 1 Geometric control
Neutrino energy transport in weak decoupling and big bang nucleosynthesis
Grohs, E; Kishimoto, C T; Paris, M W; Vlasenko, A
2015-01-01
We calculate the evolution of the early universe through the epochs of weak decoupling, weak freeze-out and big bang nucleosynthesis (BBN) by simultaneously coupling a full strong, electromagnetic, and weak nuclear reaction network with a multi-energy group Boltzmann neutrino energy transport scheme. Such an approach allows a detailed accounting of the evolution of the $\
Testing Bell inequalities with weak measurements
Shmuel Marcovitch; Benni Reznik
2011-01-18
Quantum theory is inconsistent with any local hidden variable model as was first shown by Bell. To test Bell inequalities two separated observers extract correlations from a common ensemble of identical systems. Since quantum theory does not allow simultaneous measurements of noncommuting observables, on each system every party measures a single randomly chosen observable out of a given set. Here we suggest a different approach for testing Bell inequalities that is experimentally realizable by current methods. We show that Bell inequalities can be maximally violated even when all observables are measured on each member of the ensemble. This is possible by using weak measurements that produce small disturbance, at the expense of accuracy. However, our approach does not constitute an independent test of quantum nonlocality since the local hidden variables may correlate the noise of the measurement instruments. Nevertheless, by adding a randomly chosen precise measurement at the end of every cycle of weak measurements, the parties can verify that the hidden variables were not interfering with the noise, and thus validate the suggested test.
MOSFET Operation in Weak and Moderate Inversion R.R. Harrison The MOS Transistor in Weak Inversion
Harrison, Reid R.
exponentially with decreasing gate voltage. Depletion Weak inversion Moderate inversion Strong inversion VGB VT0 axis: Weak inversion Moderate inversion Strong inversion VGB VT0 QI = -Cox(VGB VT0) log |QI| QI -exp(VGB
Rheology of weakly wetted granular materials - a comparison of experimental and numerical data
Ruediger Schwarze; Anton Gladkyy; Fabian Uhlig; Stefan Luding
2014-09-12
Shear cell simulations and experiments of weakly wetted particles (a few volume percent liquid binders) are compared, with the goal to understand their flow rheology. Application examples are cores for metal casting by core shooting made of sand and liquid binding materials. The experiments are carried out with a Couette-like rotating viscometer. The weakly wetted granular materials are made of quartz sand and small amounts of Newtonian liquids. For comparison, experiments on dry sand are also performed with a modified configuration of the viscometer. The numerical model involves spherical, monodisperse particles with contact forces and a simple liquid bridge model for individual capillary bridges between two particles. Different liquid content and properties lead to different flow rheology when measuring the shear stress-strain relations. In the experiments of the weakly wetted granular material, the apparent shear viscosity $\\eta_g$ scales inversely proportional to the inertial number $I$, for all shear rates. On the contrary, in the dry case, an intermediate scaling regime inversely quadratic in $I$ is observed for moderate shear rates. In the simulations, both scaling regimes are found for dry and wet granular material as well.
Energy Transport in Weakly Anharmonic Chains
Kenichiro Aoki; Jani Lukkarinen; Herbert Spohn
2006-02-05
We investigate the energy transport in a one-dimensional lattice of oscillators with a harmonic nearest neighbor coupling and a harmonic plus quartic on-site potential. As numerically observed for particular coupling parameters before, and confirmed by our study, such chains satisfy Fourier's law: a chain of length N coupled to thermal reservoirs at both ends has an average steady state energy current proportional to 1/N. On the theoretical level we employ the Peierls transport equation for phonons and note that beyond a mere exchange of labels it admits nondegenerate phonon collisions. These collisions are responsible for a finite heat conductivity. The predictions of kinetic theory are compared with molecular dynamics simulations. In the range of weak anharmonicity, respectively low temperatures, reasonable agreement is observed.
Modeling active electrolocation in weakly electric fish
Habib Ammari; Thomas Boulier; Josselin Garnier
2013-03-06
In this paper, we provide a mathematical model for the electrolocation in weakly electric fishes. We first investigate the forward complex conductivity problem and derive the approximate boundary conditions on the skin of the fish. Then we provide a dipole approximation for small targets away from the fish. Based on this approximation, we obtain a non-iterative location search algorithm using multi-frequency measurements. We present numerical experiments to illustrate the performance and the stability of the proposed multi-frequency location search algorithm. Finally, in the case of disk- and ellipse-shaped targets, we provide a method to reconstruct separately the conductivity, the permittivity, and the size of the targets from multi-frequency measurements.
Analysing weak orbital signals in Gaia data
Lucy, L B
2014-01-01
Anomalous orbits are found when minimum-chi^{2} estimation is applied to synthetic Gaia data for weak orbital signals - i.e., orbits whose astrometric signatures are comparable to the single-scan measurement error (Pourbaix 2002). These orbits are nearly parabolic, edge-on, and their major axes align with the line-of-sight to the observer. Such orbits violate the Copernican principle (CPr) and as such could be rejected. However, the preferred alternative is to develop a statistical technique that incorporates the CPr as a fundamental postulate. This can be achieved in the context of Bayesian estimation by defining a Copernican prior. With this development, Pourbaix's anomalous orbits no longer arise. Instead, orbits with a somewhat higher chi^{2} but which do not violate the CPr are selected. Other areas of astronomy where the investigator must analyse data from 'imperfect experiments' might similarly benefit from appropriately- defined Copernican priors.
Erythropoietin binding protein from mammalian serum
Clemons, Gisela K. (Berkeley, CA)
1997-01-01
Purified mammalian erythropoietin binding-protein is disclosed, and its isolation, identification, characterization, purification, and immunoassay are described. The erythropoietin binding protein can be used for regulation of erythropoiesis by regulating levels and half-life of erythropoietin. A diagnostic kit for determination of level of erythropoietin binding protein is also described.
Erythropoietin binding protein from mammalian serum
Clemons, G.K.
1997-04-29
Purified mammalian erythropoietin binding-protein is disclosed, and its isolation, identification, characterization, purification, and immunoassay are described. The erythropoietin binding protein can be used for regulation of erythropoiesis by regulating levels and half-life of erythropoietin. A diagnostic kit for determination of level of erythropoietin binding protein is also described. 11 figs.
Atmospheric Dispersion Effects in Weak Lensing Measurements
DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)
Plazas, Andrés Alejandro; Bernstein, Gary
2012-10-01
The wavelength dependence of atmospheric refraction causes elongation of finite-bandwidth images along the elevation vector, which produces spurious signals in weak gravitational lensing shear measurements unless this atmospheric dispersion is calibrated and removed to high precision. Because astrometric solutions and PSF characteristics are typically calibrated from stellar images, differences between the reference stars' spectra and the galaxies' spectra will leave residual errors in both the astrometric positions (dr) and in the second moment (width) of the wavelength-averaged PSF (dv) for galaxies.We estimate the level of dv that will induce spurious weak lensing signals in PSF-corrected galaxy shapes that exceed themore »statistical errors of the DES and the LSST cosmic-shear experiments. We also estimate the dr signals that will produce unacceptable spurious distortions after stacking of exposures taken at different airmasses and hour angles. We also calculate the errors in the griz bands, and find that dispersion systematics, uncorrected, are up to 6 and 2 times larger in g and r bands,respectively, than the requirements for the DES error budget, but can be safely ignored in i and z bands. For the LSST requirements, the factors are about 30, 10, and 3 in g, r, and i bands,respectively. We find that a simple correction linear in galaxy color is accurate enough to reduce dispersion shear systematics to insignificant levels in the r band for DES and i band for LSST,but still as much as 5 times than the requirements for LSST r-band observations. More complex corrections will likely be able to reduce the systematic cosmic-shear errors below statistical errors for LSST r band. But g-band effects remain large enough that it seems likely that induced systematics will dominate the statistical errors of both surveys, and cosmic-shear measurements should rely on the redder bands.« less
The Q_weak Experimental Apparatus
Qweak Collaboration; T. Allison; M. Anderson; D. Androic; D. S. Armstrong; A. Asaturyan; T. D. Averett; R. Averill; J. Balewski; J. Beaufait; R. S. Beminiwattha; J. Benesch; F. Benmokhtar; J. Bessuille; J. Birchall; E. Bonnell; J. Bowman; P. Brindza; D. B. Brown; R. D. Carlini; G. D. Cates; B. Cavness; G. Clark; J. C. Cornejo; S. Covrig Dusa; M. M. Dalton; C. A. Davis; D. C. Dean; W. Deconinck; J. Diefenbach; K. Dow; J. F. Dowd; J. A. Dunne; D. Dutta; W. S. Duvall; J. R. Echols; M. Elaasar; W. R. Falk; K. D. Finelli; J. M. Finn; D. Gaskell; M. T. W. Gericke; J. Grames; V. M. Gray; K. Grimm; F. Guo; J. Hansknecht; D. J. Harrison; E. Henderson; J. R. Hoskins; E. Ihloff; K. Johnston; D. Jones; M. Jones; R. Jones; M. Kargiantoulakis; J. Kelsey; N. Khan; P. M. King; E. Korkmaz; S. Kowalski; A. Kubera; J. Leacock; J. P. Leckey; A. R. Lee; J. H. Lee; L. Lee; Y. Liang; S. MacEwan; D. Mack; J. A. Magee; R. Mahurin; J. Mammei; J. W. Martin; A. McCreary; M. H. McDonald; M. J. McHugh; P. Medeiros; D. Meekins; J. Mei; R. Michaels; A. Micherdzinska; A. Mkrtchyan; H. Mkrtchyan; N. Morgan; J. Musson; K. E. Mesick; A. Narayan; L. Z. Ndukum; V. Nelyubin; Nuruzzaman; W. T. H. van Oers; A. K. Opper; S. A. Page; J. Pan; K. D. Paschke; S. K. Phillips; M. L. Pitt; M. Poelker; J. F. Rajotte; W. D. Ramsay; W. R. Roberts; J. Roche; P. W. Rose; B. Sawatzky; T. Seva; M. H. Shabestari; R. Silwal; N. Simicevic; G. R. Smith; S. Sobczynski; P. Solvignon; D. T. Spayde; B. Stokes; D. W. Storey; A. Subedi; R. Subedi; R. Suleiman; V. Tadevosyan; W. A. Tobias; V. Tvaskis; E. Urban; B. Waidyawansa; P. Wang; S. P. Wells; S. A. Wood; S. Yang; S. Zhamkochyan; R. B. Zielinski
2015-01-06
The Jefferson Lab Q_weak experiment determined the weak charge of the proton by measuring the parity-violating elastic scattering asymmetry of longitudinally polarized electrons from an unpolarized liquid hydrogen target at small momentum transfer. A custom apparatus was designed for this experiment to meet the technical challenges presented by the smallest and most precise ${\\vec{e}}$p asymmetry ever measured. Technical milestones were achieved at Jefferson Lab in target power, beam current, beam helicity reversal rate, polarimetry, detected rates, and control of helicity-correlated beam properties. The experiment employed 180 microA of 89% longitudinally polarized electrons whose helicity was reversed 960 times per second. The electrons were accelerated to 1.16 GeV and directed to a beamline with extensive instrumentation to measure helicity-correlated beam properties that can induce false asymmetries. Moller and Compton polarimetry were used to measure the electron beam polarization to better than 1%. The electron beam was incident on a 34.4 cm liquid hydrogen target. After passing through a triple collimator system, scattered electrons between 5.8 degrees and 11.6 degrees were bent in the toroidal magnetic field of a resistive copper-coil magnet. The electrons inside this acceptance were focused onto eight fused silica Cerenkov detectors arrayed symmetrically around the beam axis. A total scattered electron rate of about 7 GHz was incident on the detector array. The detectors were read out in integrating mode by custom-built low-noise pre-amplifiers and 18-bit sampling ADC modules. The momentum transfer Q^2 = 0.025 GeV^2 was determined using dedicated low-current (~100 pA) measurements with a set of drift chambers before (and a set of drift chambers and trigger scintillation counters after) the toroidal magnet.
Atmospheric Dispersion Effects in Weak Lensing Measurements
Plazas, Andrés Alejandro; Bernstein, Gary
2012-10-01
The wavelength dependence of atmospheric refraction causes elongation of finite-bandwidth images along the elevation vector, which produces spurious signals in weak gravitational lensing shear measurements unless this atmospheric dispersion is calibrated and removed to high precision. Because astrometric solutions and PSF characteristics are typically calibrated from stellar images, differences between the reference stars' spectra and the galaxies' spectra will leave residual errors in both the astrometric positions (dr) and in the second moment (width) of the wavelength-averaged PSF (dv) for galaxies.We estimate the level of dv that will induce spurious weak lensing signals in PSF-corrected galaxy shapes that exceed the statistical errors of the DES and the LSST cosmic-shear experiments. We also estimate the dr signals that will produce unacceptable spurious distortions after stacking of exposures taken at different airmasses and hour angles. We also calculate the errors in the griz bands, and find that dispersion systematics, uncorrected, are up to 6 and 2 times larger in g and r bands,respectively, than the requirements for the DES error budget, but can be safely ignored in i and z bands. For the LSST requirements, the factors are about 30, 10, and 3 in g, r, and i bands,respectively. We find that a simple correction linear in galaxy color is accurate enough to reduce dispersion shear systematics to insignificant levels in the r band for DES and i band for LSST,but still as much as 5 times than the requirements for LSST r-band observations. More complex corrections will likely be able to reduce the systematic cosmic-shear errors below statistical errors for LSST r band. But g-band effects remain large enough that it seems likely that induced systematics will dominate the statistical errors of both surveys, and cosmic-shear measurements should rely on the redder bands.
Magnified Weak Lensing Cross Correlation Tomography
Ulmer, Melville P., Clowe, Douglas I.
2010-11-30
This project carried out a weak lensing tomography (WLT) measurement around rich clusters of galaxies. This project used ground based photometric redshift data combined with HST archived cluster images that provide the WLT and cluster mass modeling. The technique has already produced interesting results (Guennou et al, 2010,Astronomy & Astrophysics Vol 523, page 21, and Clowe et al, 2011 to be submitted). Guennou et al have validated that the necessary accuracy can be achieved with photometric redshifts for our purposes. Clowe et al titled "The DAFT/FADA survey. II. Tomographic weak lensing signal from 10 high redshift clusters," have shown that for the **first time** via this purely geometrical technique, which does not assume a standard rod or candle, that a cosmological constant is **required** for flat cosmologies. The intent of this project is not to produce the best constraint on the value of the dark energy equation of state, w. Rather, this project is to carry out a sustained effort of weak lensing tomography that will naturally feed into the near term Dark Energy Survey (DES) and to provide invaluable mass calibration for that project. These results will greatly advance a key cosmological method which will be applied to the top-rated ground-based project in the Astro2020 decadal survey, LSST. Weak lensing tomography is one of the key science drivers behind LSST. CO-I Clowe is on the weak lensing LSST committee, and senior scientist on this project, at FNAL James Annis, plays a leading role in the DES. This project has built on successful proposals to obtain ground-based imaging for the cluster sample. By 1 Jan, it is anticipated the project will have accumulated complete 5-color photometry on 30 (or about 1/3) of the targeted cluster sample (public webpage for the survey is available at http://cencos.oamp.fr/DAFT/ and has a current summary of the observational status of various clusters). In all, the project has now been awarded the equivalent of over 60 nights on 4-m class telescopes, which gives concrete evidence of strong community support for this project. The WLT technique is based on the dependence of the gravitational shear signal on the angular diameter distances between the observer, the lens, and the lensed galaxy to measure cosmological parameters. By taking the ratio of measured shears of galaxies with different redshifts around the same lens, one obtains a measurement of the ratios of the angular diameter distances involved. Making these observations over a large range of lenses and background galaxy redshifts will measure the history of the expansion rate of the universe. Because this is a purely geometric measurement, it is insensitive to any form of evolution of objects or the necessity to understand the physics in the early universe. Thus, WLT was identified by the Dark Energy Task Force as perhaps the best method to measure the evolution of DE. To date, however, the conjecture of the DETF has not been experimentally verified, but will be by the proposed project. The primary reason for the lack of tomography measurements is that one must have an exceptional data-set to attempt the measurement. One needs both extremely good seeing (or space observations) in order to minimize the point spread function smearing corrections on weak lensing shear measurements and deep, multi-color data, from B to z, to measure reliable photometric redshifts of the background galaxies being lensed (which are typically too faint to obtain spectroscopic redshifts). Because the entire process from multi-drizzling the HST images, and then creating shear maps, to gathering the necessary ground based observations, to generating photo-zs and then carrying out the tomography is a complicated task, until the creation of our team, nobody has taken the time to connect all the levels of expertise necessary to carry out this project based on HST archival data. Our data are being used in 2 Ph.D. theses. Kellen Murphy, at Ohio University, is using the tomography data along with simulations in a thesis expected to be completed in Jun
Fisher, Andrew J.
1) binds transition metals and rare earths with extreme stability under physiological conditionsA Rare Earth-DOTA-Binding Antibody: Probe Properties and Binding Affinity across the Lanthanide affinity and exquisite specificity.1 An antibody that binds rare earth complexes selectively could be used
Synthetic heparin-binding factor analogs
Pena, Louis A. (Poquott, NY); Zamora, Paul O. (Gaithersburg, MD); Lin, Xinhua (Plainview, NY); Glass, John D. (Shoreham, NY)
2010-04-20
The invention provides synthetic heparin-binding growth factor analogs having at least one peptide chain, and preferably two peptide chains branched from a dipeptide branch moiety composed of two trifunctional amino acid residues, which peptide chain or chains bind a heparin-binding growth factor receptor and are covalently bound to a non-signaling peptide that includes a heparin-binding domain, preferably by a linker, which may be a hydrophobic linker. The synthetic heparin-binding growth factor analogs are useful as pharmaceutical agents, soluble biologics or as surface coatings for medical devices.
Weak gravitational lensing with the Square Kilometre Array
Brown, M L; Camera, S; Harrison, I; Joachimi, B; Metcalf, R B; Pourtsidou, A; Takahashi, K; Zuntz, J A; Abdalla, F B; Bridle, S; Jarvis, M; Kitching, T D; Miller, L; Patel, P
2015-01-01
We investigate the capabilities of various stages of the SKA to perform world-leading weak gravitational lensing surveys. We outline a way forward to develop the tools needed for pursuing weak lensing in the radio band. We identify the key analysis challenges and the key pathfinder experiments that will allow us to address them in the run up to the SKA. We identify and summarize the unique and potentially very powerful aspects of radio weak lensing surveys, facilitated by the SKA, that can solve major challenges in the field of weak lensing. These include the use of polarization and rotational velocity information to control intrinsic alignments, and the new area of weak lensing using intensity mapping experiments. We show how the SKA lensing surveys will both complement and enhance corresponding efforts in the optical wavebands through cross-correlation techniques and by way of extending the reach of weak lensing to high redshift.
Weak nuclear forces cause the strong nuclear force
E. L. Koschmieder
2007-12-11
We determine the strength of the weak nuclear force which holds the lattices of the elementary particles together. We also determine the strength of the strong nuclear force which emanates from the sides of the nuclear lattices. The strong force is the sum of the unsaturated weak forces at the surface of the nuclear lattices. The strong force is then about ten to the power of 6 times stronger than the weak force between two lattice points.
Graphene transparency in weak magnetic fields
David Valenzuela; Saúl Hernández-Ortiz; Marcelo Loewe; Alfredo Raya
2014-10-20
We carry out an explicit calculation of the vacuum polarization tensor for an effective low-energy model of monolayer graphene in the presence of a weak magnetic field of intensity $B$ perpendicularly aligned to the membrane. By expanding the quasiparticle propagator in the Schwinger proper time representation up to order $(eB)^2$, where $e$ is the unit charge, we find an explicitly transverse tensor, consistent with gauge invariance. Furthermore, assuming that graphene is radiated with monochromatic light of frequency $\\omega$ along the external field direction, from the modified Maxwell's equations we derive the intensity of transmitted light and the angle of polarization rotation in terms of the longitudinal ($\\sigma_{xx}$) and transverse ($\\sigma_{xy}$) conductivities. Corrections to these quantities, both calculated and measured, are of order $(eB)^2/\\omega^4$. Our findings generalize and complement previously known results reported in literature regarding the light absorption problem in graphene from the experimental and theoretical points of view, with and without external magnetic fields.
Perturbations of Weakly Resonant Power System Electromechanical Modes
1 Perturbations of Weakly Resonant Power System Electromechanical Modes Ian Dobson, Senior Member. The possible perturbations are illustrated with interactions between electromechanical modes in a 4 bus power
Origins of weak lensing systematics, and requirements on future...
Office of Scientific and Technical Information (OSTI)
Journal Article: Origins of weak lensing systematics, and requirements on future instrumentation (or knowledge of instrumentation) Citation Details In-Document Search Title:...
Binding and structure of tetramers in the scaling limit
Hadizadeh, M R; Tomio, L; Delfino, A; Frederico, T
2011-01-01
The momentum-space structure of the Faddeev-Yakubovsky (FY) components of weakly-bound tetramers is investigated at the unitary limit using a renormalized zero-range two-body interaction. The results, obtained by considering a given trimer level with binding energy $B_3$, provide further support to a universal scaling function relating the binding energies of two successive tetramer states. The correlated scaling between the tetramer energies comes from the sensitivity of the four-boson system to a short-range four-body scale. Each excited $N-$th tetramer energy $B_4^{(N)}$ moves as the short-range four-body scale changes, while the trimer properties are kept fixed, with the next excited tetramer $B_4^{(N+1)}$ emerging from the atom-trimer threshold for a universal ratio $B_4^{(N)}/B_3 = B_4^ {(N)}/B_4^{(N+1)} \\simeq 4.6$, which does not depend on $N$. We show that both channels of the FY decomposition [atom-trimer ($K-$type) and dimer-dimer ($H-$type)] present high momentum tails, which reflect the short-ran...
Binding and structure of tetramers in the scaling limit
M. R. Hadizadeh; M. T. Yamashita; L. Tomio; A. Delfino; T. Frederico
2012-01-17
The momentum-space structure of the Faddeev-Yakubovsky (FY)components of weakly-bound tetramers is investigated at the unitary limit using a renormalized zero-range two-body interaction. The results, obtained by considering a given trimer level with binding energy $B_3$, provide further support to a universal scaling function relating the binding energies of two successive tetramer states. The correlated scaling between the tetramer energies comes from the sensitivity of the four-boson system to a short-range four-body scale. Each excited $N-$th tetramer energy $B_4^{(N)}$ moves as the short-range four-body scale changes, while the trimer properties are kept fixed, with the next excited tetramer $B_4^{(N+1)}$ emerging from the atom-trimer threshold for a universal ratio $B_4^{(N)}/B_3 = B_4^ {(N)}/B_4^{(N+1)} \\simeq 4.6$, which does not depend on $N$. We show that both channels of the FY decomposition [atom-trimer ($K-$type) and dimer-dimer ($H-$type)] present high momentum tails, which reflect the short-range four-body scale. We also found that the $H-$channel is favored over $K-$channel at low momentum when the four-body momentum scale largely overcomes the three-body one.
The COS Stream Ciphers are Extremely Weak Steve Babbage
International Association for Cryptologic Research (IACR)
The COS Stream Ciphers are Extremely Weak Steve Babbage Vodafone Group R&D, Newbury, UK steve.babbage@vodafone.com Abstract: A new family of very fast stream ciphers called COS (for "crossing over system") has been. In this note we show that the COS ciphers are very weak indeed -- it requires negligible effort to reconstruct
The COS Stream Ciphers are Extremely Weak Steve Babbage
International Association for Cryptologic Research (IACR)
The COS Stream Ciphers are Extremely Weak Steve Babbage Vodafone Group R&D, Newbury, UK steve.babbage@vodafone.com Abstract: A new family of very fast stream ciphers called COS (for ``crossing over system'') has been. In this note we show that the COS ciphers are very weak indeed --- it requires negligible effort to reconstruct
Higgs Production via Gluon-Induced Weak Boson Fusion
Jens Vollinga
2008-09-22
We present a calculation that allows for an estimation of the NNLO contributions to the Higgs production in the weak boson fusion channel. A possible deterioration of this important channel for the Higgs discoveries at the LHC can be ruled out by this calculation due to the small remaining cross section after the weak boson cuts.
CH-{\\pi} interaction-induced deep orbital deformation in a benzene-methane weak binding system
Li, Jianfu
2015-01-01
The nonbonding interaction between benzene and methane, called CH-{\\pi} interaction, plays an important role in physical, chemical, and biological fields. CH-{\\pi} interaction can decrease the system total energy and promote the formation of special geometric configurations. This work investigates systemically the orbital distribution and composition of the benzene-methane complex for the first time using ab initio calculation based on different methods and basis sets. Surprisingly, we find strong deformation in HOMO-4 and LUMO+2 induced by CH-{\\pi} interaction, extending the general view that nonbonding interaction does not cause orbital change of molecules.
International Association for Cryptologic Research (IACR)
Statistical weaknesses in 20 RC4-like algorithms and (probably) the simplest algorithm free from statistical weaknesses in 20 RC4-like algorithms including the original RC4, RC4A, PC-RC4 and others. This is achieved using a simple statistical test. We found only one algorithm which was able to pass the test
Docking Small Ligands in Flexible Binding Sites
Caflisch, Amedeo
binding site. For all three systems the best minima in terms of free energy have a root mean square 3100-043423.95 Contractrgrant sponsor: Swiss Federal Office of Public Health; contractrgrant number the conformational space that has to be searched. There are known examples where the empty receptor cannot bind
Capture and release of mixed acid gasses with binding organic liquids
Heldebrant, David J. (Richland, WA); Yonker, Clement R. (Kennewick, WA)
2010-09-21
Reversible acid-gas binding organic liquid systems that permit separation and capture of one or more of several acid gases from a mixed gas stream, transport of the liquid, release of the acid gases from the ionic liquid and reuse of the liquid to bind more acid gas with significant energy savings compared to current aqueous systems. These systems utilize acid gas capture compounds made up of strong bases and weak acids that form salts when reacted with a selected acid gas, and which release these gases when a preselected triggering event occurs. The various new materials that make up this system can also be included in various other applications such as chemical sensors, chemical reactants, scrubbers, and separators that allow for the specific and separate removal of desired materials from a gas stream such as flue gas.
Weak Quenched Limiting Distributions for One-dimensional RWRE
Jonathon Peterson
2010-09-12
Sep 13, 2010 ... Ladder locations {?n} defined by ?0 = 0, ?n := inf{i > ?n?1 : V(i) < V(?n?1)} .... Weak quenched limits. Proofs. Heuristics of Quenched Limit Laws.
Ultra-weak sector, Higgs boson mass, and the dilaton
Allison, Kyle; Hill, Christopher T.; Ross, Graham G.
2014-09-26
The Higgs boson mass may arise from a portal coupling to a singlet field $\\sigma$ which has a very large VEV $f \\gg m_\\text{Higgs}$. This requires a sector of "ultra-weak" couplings $\\zeta_i$, where $\\zeta_i \\lesssim m_\\text{Higgs}^2 / f^2$. Ultra-weak couplings are technically naturally small due to a custodial shift symmetry of $\\sigma$ in the $\\zeta_i \\rightarrow 0$ limit. The singlet field $\\sigma$ has properties similar to a pseudo-dilaton. We engineer explicit breaking of scale invariance in the ultra-weak sector via a Coleman-Weinberg potential, which requires hierarchies amongst the ultra-weak couplings.
Supplementary Information for Simulating weak localization in superconducting quantum circuit
Martinis, John M.
Supplementary Information for Simulating weak localization in superconducting quantum circuit Yu-type entangled state in superconducting quantum circuits.[2, 3] We rst generated a photon in the readout qubit
Ultra-weak sector, Higgs boson mass, and the dilaton
DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)
Allison, Kyle; Hill, Christopher T.; Ross, Graham G.
2014-11-01
The Higgs boson mass may arise from a portal coupling to a singlet field $\\sigma$ which has a very large VEV $f \\gg m_\\text{Higgs}$. This requires a sector of "ultra-weak" couplings $\\zeta_i$, where $\\zeta_i \\lesssim m_\\text{Higgs}^2 / f^2$. Ultra-weak couplings are technically naturally small due to a custodial shift symmetry of $\\sigma$ in the $\\zeta_i \\rightarrow 0$ limit. The singlet field $\\sigma$ has properties similar to a pseudo-dilaton. We engineer explicit breaking of scale invariance in the ultra-weak sector via a Coleman-Weinberg potential, which requires hierarchies amongst the ultra-weak couplings.
Nuclear Constraints on the Weak Nucleon-Nucleon Interaction
W. C. Haxton
2008-02-21
I discuss the current status of efforts to constrain the strangeness-conserving weak hadronic interaction, which can be isolated in nuclear systems because of the associated parity violation.
Weak Identification in Maximum Likelihood: A Question of Information
Andrews, Isaiah
In this paper we connect the discrepancy between two estimates of Fisher information, one based on the quadratic variation of the score and the other based on the negative Hessian of the log-likelihood, to weak identification. ...
Evidence for a Weak Iron Core at Earth's Center
Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)
Evidence for a Weak Iron Core at Earth's Center Print Seismic waves that pass through the center of the Earth travel faster going from pole to pole than along the equatorial...
Evidence for a Weak Iron Core at Earth's Center
Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)
Evidence for a Weak Iron Core at Earth's Center Print Wednesday, 30 April 2014 00:00 Seismic waves that pass through the center of the Earth travel faster going from pole to pole...
Improved flow cytometer measurement of binding assays
Saunders, G.C.
1984-05-30
The invention relates to a method of measuring binding assays carried out with different size particles wherein the binding assay sample is run through a flow cytometer without separating the sample from the marking agent. The amount of a binding reactant present in a sample is determined by providing particles with a coating of binder and also a known quantity of smaller particles with a coating of binder reactant. The binding reactant is the same as the binding reactant present in the sample. The smaller particles also contain a fluorescent chemical. The particles are combined with the sample and the binding reaction is allowed to occur for a set length of time followed by combining the smaller particles with the mixture of the particles and the sample produced and allowing the binding reactions to proceed to equilibrium. The fluorescence and light scatter of the combined mixture is then measured as the combined mixture passes through a flow cytometer equipped with a laser to bring about fluorescence, and the number and strength of fluorescent events are compared. A similar method is also provided for determining the amount of antigen present in the sample by providing spheres with an antibody coating and some smaller spheres with an antigen coating. (LEW)
Bipolaron and N-Polaron Binding Energies
Frank, Rupert L. [Department of Mathematics, Princeton University, Washington Road, Princeton, New Jersey 08544 (United States); Lieb, Elliott H. [Department of Mathematics, Princeton University, Washington Road, Princeton, New Jersey 08544 (United States); Department of Physics, Princeton University, P.O. Box 708, Princeton, New Jersey 08542 (United States); Seiringer, Robert [Department of Physics, Princeton University, P.O. Box 708, Princeton, New Jersey 08542 (United States); Thomas, Lawrence E. [Department of Mathematics, University of Virginia, Charlottesville, Virginia 22904 (United States)
2010-05-28
The binding of polarons, or its absence, is an old and subtle topic. Here we prove two things rigorously. First, the transition from many-body collapse to the existence of a thermodynamic limit for N polarons occurs precisely at U=2{alpha}, where U is the electronic Coulomb repulsion and {alpha} is the polaron coupling constant. Second, if U is large enough, there is no multipolaron binding of any kind. Considering the known fact that there is binding for some U>2{alpha}, these conclusions are not obvious and their proof has been an open problem for some time.
Sequestering Uranium from Seawater: Binding Strength and Modes...
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Sequestering Uranium from Seawater: Binding Strength and Modes of Uranyl Complexes with Glutarimidedioxime Sequestering Uranium from Seawater: Binding Strength and Modes of Uranyl...
Ratcliffe, H. Brady, C. S.; Che Rozenan, M. B.; Nakariakov, V. M.
2014-12-15
Quasilinear theory has long been used to treat the problem of a weak electron beam interacting with plasma and generating Langmuir waves. Its extension to weak-turbulence theory treats resonant interactions of these Langmuir waves with other plasma wave modes, in particular, ion-sound waves. These are strongly damped in plasma of equal ion and electron temperatures, as sometimes seen in, for example, the solar corona and wind. Weak turbulence theory is derived in the weak damping limit, with a term describing ion-sound wave damping then added. In this paper, we use the EPOCH particle-in-cell code to numerically test weak turbulence theory for a range of electron-ion temperature ratios. We find that in the cold ion limit, the results agree well, but for increasing ion temperature the three-wave resonance becomes broadened in proportion to the ion-sound wave damping rate. Additionally, we establish lower limits on the number of simulation particles needed to accurately reproduce the electron and wave distributions in their saturated states and to reproduce their intermediate states and time evolution. These results should be taken into consideration in, for example, simulations of plasma wave generation in the solar corona of Type III solar radio bursts from the corona to the solar wind and in weak turbulence investigations of ion-acoustic lines in the ionosphere.
Metal-binding polymesr as chelating agents
Mohammadi, Zahra
2011-04-11
, high affinity binding of toxic metals by these functionalized hydrogels offers potential applications in waste water treatment and may enable applications in acute metal poisoning. Finally, a unique synthetic methodology using similar metal chelating...
Hardware device binding and mutual authentication
Hamlet, Jason R; Pierson, Lyndon G
2014-03-04
Detection and deterrence of device tampering and subversion by substitution may be achieved by including a cryptographic unit within a computing device for binding multiple hardware devices and mutually authenticating the devices. The cryptographic unit includes a physically unclonable function ("PUF") circuit disposed in or on the hardware device, which generates a binding PUF value. The cryptographic unit uses the binding PUF value during an enrollment phase and subsequent authentication phases. During a subsequent authentication phase, the cryptographic unit uses the binding PUF values of the multiple hardware devices to generate a challenge to send to the other device, and to verify a challenge received from the other device to mutually authenticate the hardware devices.
Searching for massive clusters in weak lensing surveys
Takashi Hamana; Masahiro Takada; Naoki Yoshida
2004-02-02
We explore the ability of weak lensing surveys to locate massive clusters. We use both analytic models of dark matter halos and mock weak lensing surveys generated from a large cosmological N-body simulation. The analytic models describe average properties of weak lensing halos and predict the number counts, enabling us to compute an effective survey selection function. We test the model prediction for the peak number counts in weak lensing mass maps against the mock numerical data, and find that the noise due to intrinsic galaxy ellipticities causes a systematic effect which increases the peak counts. We develop a correction scheme for the systematic effect in an empirical manner, and show that, after the correction, the model prediction agrees well with the mock data. The mock data is also used to examine the completeness and efficiency of the weak lensing halo search with fully taking into account the noise and the projection effect by large-scale structures. We show that the detection threshold of S/N=4-5 gives an optimal balance between completeness and efficiency. Our results suggest that, for a weak lensing survey with a galaxy number density of ng=30/arcmin^2 with a mean redshift z=1, the mean number of peaks in the 10sq deg area is N_peak=62 for a detection threshold S/N=4. The contamination rate is 42%, and thus, on average, 36 out of 62 peaks (at least) are signals from real halos. Weak lensing surveys thus provide a reasonably efficient way to searching for massive clusters.
RNA binding protein and binding site useful for expression of recombinant molecules
Mayfield, Stephen (Cardiff, CA)
2000-01-01
The present invention relates to a gene expression system in eukaryotic and prokaryotic cells, preferably plant cells and intact plants. In particular, the invention relates to an expression system having a RB47 binding site upstream of a translation initiation site for regulation of translation mediated by binding of RB47 protein, a member of the poly(A) binding protein family. Regulation is further effected by RB60, a protein disulfide isomerase. The expression system is capable of functioning in the nuclear/cytoplasm of cells and in the chloroplast of plants. Translation regulation of a desired molecule is enhanced approximately 100 fold over that obtained without RB47 binding site activation.
RNA binding protein and binding site useful for expression of recombinant molecules
Mayfield, Stephen P.
2006-10-17
The present invention relates to a gene expression system in eukaryotic and prokaryotic cells, preferably plant cells and intact plants. In particular, the invention relates to an expression system having a RB47 binding site upstream of a translation initiation site for regulation of translation mediated by binding of RB47 protein, a member of the poly(A) binding protein family. Regulation is further effected by RB60, a protein disulfide isomerase. The expression system is capable of functioning in the nuclear/cytoplasm of cells and in the chloroplast of plants. Translation regulation of a desired molecule is enhanced approximately 100 fold over that obtained without RB47 binding site activation.
Lossy compression of weak lensing data (Journal Article) | SciTech...
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Lossy compression of weak lensing data Citation Details In-Document Search Title: Lossy compression of weak lensing data You are accessing a document from the Department of...
Lossy compression of weak lensing data (Journal Article) | SciTech...
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Journal Article: Lossy compression of weak lensing data Citation Details In-Document Search Title: Lossy compression of weak lensing data Future orbiting observatories will survey...
Designing Weak Lensing Surveys: A Generalised Eigenmode Analysis
Martin Kilbinger; Dipak Munshi
2005-11-17
We study the estimators of various second-order weak lensing statistics such as the shear correlation functions xi_\\pm and the aperture mass dispersion which can directly be constructed from weak lensing shear maps. We compare the efficiency with which these estimators can be used to constrain cosmological parameters. To this end we introduce the Karhunen-Loeve (KL) eigenmode analysis techniques for weak lensing surveys. These tools are shown to be very effective as a diagnostics for optimising survey strategies. The usefulness of these tools to study the effect of angular binning, the depth and width of the survey and noise contributions due to intrinsic ellipticities and number density of source galaxies on the estimation of cosmological parameters is demonstrated. Results from independent analysis of various parameters and joint estimations are compared. We also study how degeneracies among various cosmological and survey parameters affect the eigenmodes associated with these parameters.
Gravitational Interaction of Higgs Boson and Weak Boson Scattering
Zhong-Zhi Xianyu; Jing Ren; Hong-Jian He
2013-11-04
With the LHC discovery of a 125 GeV Higgs-like boson, we study gravitational interaction of the Higgs boson via the unique dimension-4 operator involving Higgs doublet and scalar curvature, $\\,\\xi H^\\dag H R\\,$, with nonminimal coupling $\\,\\xi\\,$. This Higgs portal term can be transformed away in Einstein frame and induces gauge-invariant effective interactions in the Higgs sector. We study the weak boson scattering in Einstein frame, and explicitly demonstrate the longitudinal-Goldstone boson equivalence theorem in the presence of $\\,\\xi\\,$ coupling. With these, we derive unitarity bound on the Higgs gravitational coupling $\\,\\xi\\,$ in Einstein frame, which is stronger than that inferred from the current LHC Higgs measurements. We further study $\\xi$-dependent weak boson scattering cross sections at TeV scale, and propose a new LHC probe of the Higgs-gravity coupling $\\,\\xi\\,$ via weak boson scattering experiments.
Separating weak lensing and intrinsic alignments using radio observations
Whittaker, Lee; Battye, Richard A
2015-01-01
We discuss methods for performing weak lensing using radio observations to recover information about the intrinsic structural properties of the source galaxies. Radio surveys provide unique information that can benefit weak lensing studies, such as HI emission, which may be used to construct galaxy velocity maps, and polarized synchrotron radiation; both of which provide information about the unlensed galaxy and can be used to reduce galaxy shape noise and the contribution of intrinsic alignments. Using a proxy for the intrinsic position angle of an observed galaxy, we develop techniques for cleanly separating weak gravitational lensing signals from intrinsic alignment contamination in forthcoming radio surveys. Random errors on the intrinsic orientation estimates introduce biases into the shear and intrinsic alignment estimates. However, we show that these biases can be corrected for if the error distribution is accurately known. We demonstrate our methods using simulations, where we reconstruct the shear an...
Weak Measurement and Feedback in Superconducting Quantum Circuits
K. W. Murch; R. Vijay; I. Siddiqi
2015-07-16
We describe the implementation of weak quantum measurements in superconducting qubits, focusing specifically on transmon type devices in the circuit quantum electrodynamics architecture. To access this regime, the readout cavity is probed with on average a single microwave photon. Such low-level signals are detected using near quantum-noise-limited superconducting parametric amplifiers. Weak measurements yield partial information about the quantum state, and correspondingly do not completely project the qubit into an eigenstate. As such, we use the measurement record to either sequentially reconstruct the quantum state at a given time, yielding a quantum trajectory, or to close a direct quantum feedback loop, stabilizing Rabi oscillations indefinitely.
Weak Measurement and Feedback in Superconducting Quantum Circuits
K. W. Murch; R. Vijay; I. Siddiqi
2015-07-28
We describe the implementation of weak quantum measurements in superconducting qubits, focusing specifically on transmon type devices in the circuit quantum electrodynamics architecture. To access this regime, the readout cavity is probed with on average a single microwave photon. Such low-level signals are detected using near quantum-noise-limited superconducting parametric amplifiers. Weak measurements yield partial information about the quantum state, and correspondingly do not completely project the qubit into an eigenstate. As such, we use the measurement record to either sequentially reconstruct the quantum state at a given time, yielding a quantum trajectory, or to close a direct quantum feedback loop, stabilizing Rabi oscillations indefinitely.
Gap asymptotics in a weakly bent leaky quantum wire
Pavel Exner; Sylwia Kondej
2015-06-24
The main question studied in this paper concerns the weak-coupling behavior of the geometrically induced bound states of singular Schr\\"odinger operators with an attractive $\\delta$ interaction supported by a planar, asymptotically straight curve $\\Gamma$. We demonstrate that if $\\Gamma$ is only slightly bent or weakly deformed, then there is a single eigenvalue and the gap between it and the continuum threshold is in the leading order proportional to the fourth power of the bending angle, or the deformation parameter. For comparison, we analyze the behavior of a general geometrical induced eigenvalue in the situation when one of the curve asymptotes is wiggled.
The cosmology dependence of weak lensing cluster counts
Laura Marian; Robert E. Smith; Gary M. Bernstein
2009-06-30
We present the main results of a numerical study of weak lensing cluster counting. We examine the scaling with cosmology of the projected-density-peak mass function. Our main conclusion is that the projected-peak and the three-dimensional mass functions scale with cosmology in an astonishingly close way. This means that, despite being derived from a two-dimensional field, the weak lensing cluster abundance can be used to constrain cosmology in the same way as the three-dimensional mass function probed by other types of surveys.
Lesch, K.P.; Schott, W.; Gross, S.
1987-09-01
The existence of estrogen receptors in human meningiomas has long been a controversial issue. This may be explained, in part, by apparent heterogeneity of estrogen binding sites in meningioma tissue. In this study, estrogen receptors were determined in 58 meningiomas with an enzyme immunoassay using monoclonal antibodies against human estrogen receptor protein (estrophilin) and with a sensitive radioligand binding assay using /sup 125/I-labeled estradiol (/sup 125/I-estradiol) as radioligand. Low levels of estrophilin immunoreactivity were found in tumors from 62% of patients, whereas radioligand binding activity was demonstrated in about 46% of the meningiomas examined. In eight (14%) tissue samples multiple binding sites for estradiol were observed. The immunoreactive binding sites correspond to the classical, high affinity estrogen receptors: the Kd for /sup 125/I-estradiol binding to the receptor was approximately 0.2 nM and the binding was specific for estrogens. The second, low affinity class of binding sites considerably influenced measurement of the classical receptor even at low ligand concentrations. The epidemiological and clinical data from patients with meningiomas, and the existence of specific estrogen receptors confirmed by immunochemical detection, may be important factors in a theory of oncogenesis.
Show No Weakness: Sequentially Consistent Specifications of TSO Libraries
Gotsman, Alexey
Show No Weakness: Sequentially Consistent Specifications of TSO Libraries Alexey Gotsman1.g., for those that are data-race free (DRF). However, performance-critical libraries often violate, it is important for these libraries to protect their otherwise well-behaved clients from the weaker memory model
Corrigendum and addendum. Modeling weakly nonlinear acoustic wave propagation
DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)
Christov, Ivan; Christov, C. I.; Jordan, P. M.
2014-12-18
This article presents errors, corrections, and additions to the research outlined in the following citation: Christov, I., Christov, C. I., & Jordan, P. M. (2007). Modeling weakly nonlinear acoustic wave propagation. The Quarterly Journal of Mechanics and Applied Mathematics, 60(4), 473-495.
Weak interactions of quarks and leptons: experimental status
Wojcicki, S.
1984-09-01
The present experimental status of weak interactions is discussed with emphasis on the problems and questions and on the possible lines of future investigations. Major topics include; (1) the quark mixing matrix, (2) CP violation, (3) rare decays, (4) the lepton sector, and (5) right handed currents. 118 references. (WHK)
Periodic Orbits in Triaxial Galaxies with Weak Cusps
Tema Fridman; David Merritt
1997-05-19
The orbital structure of triaxial models with weak central density cusps, $\\rho\\propto r^{-\\gamma}, gamma fish boxlets in the $x-z$ (long axis-short axis) plane are stable over a wide range of model parameters. The boxlets in the $x-y$ and $y-z$ planes are generally vertically unstable.
Weakly dispersive hydraulic flows in a contraction --Nonlinear stability analysis
Ee, Bernard Kuowei
match an asymptotically flat upstream subcritical state with a similar downstream supercritical state of hydraulic transitions connecting upstream solitary wave-trains and a downstream plateau or steady downstream and their corresponding linear stability were considered. Let the upstream and downstream height of a weakly dispersive
Security weakness in the Proof of Storage with Deduplication
International Association for Cryptologic Research (IACR)
) scheme for a secure and efficient cloud storage service [1]. Ex- ploiting the public verifiability [2Security weakness in the Proof of Storage with Deduplication Youngjoo Shin1 , Junbeom Hur2@cau.ac.kr Abstract. Achieving both security and efficiency is the challenging issue for a data outsourcing service
Tachyon warm inflationary universe model in the weak dissipative regime
Sergio del Campo; Ramon Herrera; Joel Saavedra
2008-12-05
Warm inflationary universe model in a tachyon field theory is studied in the weak dissipative regime. We develop our model for an exponential potential and the dissipation parameter $\\Gamma=\\Gamma_0$=constant. We describe scalar and tensor perturbations for this scenario.
Early Results from the Q{sub weak} Experiment
Androic, D.; Armstrong, D.S.; Asaturyan, A.; Averett, T.; Balewski, J.; Beaufait, J.; Beminiwattha, R.S.; Benesch, J.; Benmokhtar, F.; Birchall, J.; Carlini, R.D.; Cates, G.D.; Cornejo, J.C.; Covrig, S.; Dalton, M.M.; Davis, C.A.; Deconinck, W.; Diefenbach, J.; Dowd, J.F.; Dunne, J.A.; Dutta, D.; Duvall, W.S.; Elaasar, M.; Falk, W.R.; Finn, J.M.; Forest, T.; Gaskel, D.; Gericke, M.T.W.; Grames, J.; Gray, V.M.; Grimm, K.; Guo, F.; Hoskins, J.R.; Johnston, K.; Jones, D.; Jones, M.; Jones, R.; Kargiantoulakis, M.; King, P.M.; Korkmaz, E.; Kowalski, S.; Leacock, J.; Leckey, J.; Lee, A.R.; Lee, J.H.; Lee, L.; MacEwan, S.; Mack, D.; Magee, J.A.; Mahurin, R.; Mammei, J.; Martin, J.; McHugh, M.J.; Meekins, D.; Mei, J.; Michaels, R.; Micherdzinska, A.; Mkrtchyan, A.; Mkrtchyan, H.; Morgan, N.; Myers, K.E.; Narayan, A.; Ndukum, L.Z.; Nelyubin, V.; W T H, Nuruzzaman; Oers, van; Opper, A.K.; Page, S.A.; Pan, J.; Paschke, K.; Phillips, S.K.; Pitt, M.L.; Poelker, M.; Rajotte, J.F.; Ramsay, W.D.; Roche, J.; Sawatzky, B.; Seva, T.; Shabestari, M.H.; Silwal, R.; Simicevic, N.; Smith, G.R.; Solvignon, P.; Spayde, D.T.; Subedi, A.; Subedi, R.; Suleiman, R.; Tadevosyan, V.; Tobias, W.A.; Tvaskis, V.; Waidyawansa, B.; Wang, P.; Wells, S.P.; Wood, S.A.; Yang, S.; Young, R.D.; Zhamkochyan, S.
2014-03-01
A subset of results from the recently completed Jefferson Lab Q{sub weak} experiment are reported. This experiment, sensitive to physics beyond the Standard Model, exploits the small parity-violating asymmetry in elastic {vector e}p scattering to provide the first determination of the protons weak charge Q{sub w}{sup p}. The experiment employed a 180 {micro}A longitudinally polarized 1.16 GeV electron beam on a 35 cm long liquid hydrogen target. Scattered electrons corresponding to Q{sup 2} of 0.025 GeV{sup 2} were detected in eight Cerenkov detectors arrayed symmetrically around the beam axis. The goals of the experiment were to provide a measure of Q{sub w}{sup p} to 4.2 percent (combined statistical and systematic error), which implies a measure of sin2(thetaw) at the level of 0.3 percent, and to help constrain the vector weak quark charges C{sub 1u} and C{sub 1d}. The experimental method is described, with particular focus on the challenges associated with the worlds highest power LH{sub 2} target. The new constraints on C{sub 1u} and C{sub 1d} provided by the subset of the experiments data analyzed to date will also be shown, together with the extracted weak charge of the neutron.
First Determination of the Weak Charge of the Proton
Balewski, Jan T.
The Q[subscript weak] experiment has measured the parity-violating asymmetry in e? p elastic scattering at Q[superscript 2] = 0.025?(GeV/c)[superscript 2], employing 145???A of 89% longitudinally polarized electrons on a ...
Lyapunov Exponents and Uniform Weak Normally Repelling Invariant Sets
Smith, Hal
Lyapunov Exponents and Uniform Weak Normally Repelling Invariant Sets Paul Leonard Salceanu and Hal repelling in directions normal to the boundary in which M resides provided all normal Lyapunov exponents that Lyapunov exponents can be used to establish the requisite repelling properties for both discrete
Higgs Production by Gluon initiated Weak Boson Fusion
M. M. Weber
2007-09-17
The gluon-gluon induced terms for Higgs production through weak-boson fusion are calculated. They form a finite and gauge-invariant subset of the NNLO corrections in the strong coupling constant. This is also the lowest order with sizeable t-channel colour exchange contributions, leading to additional hadronic activity between the outgoing jets.
Swelling Dynamics of Multilayer Films of Weak Polyelectrolytes
Barrett, Christopher
Swelling Dynamics of Multilayer Films of Weak Polyelectrolytes Oleh M. Tanchak and Christopher J humidity. Introduction Polymer multilayers can be prepared by the sequen- tial electrostatic adsorption of oppositely charged poly- electrolytes onto a substrate. Through control of various assembly parameters one
Chisholm, J S R
1984-01-01
Spin gauge theory of the first generation ; 2, basic theory of strong, weak, and electromagnetic interactions
Formation of slot-shaped borehole breakout within weakly cemented sandstones
Nakagawa, Seiji; Tomutsa, Liviu; Myer, Larry R.
2008-01-01
within weakly cemented sandstones Seiji Nakagawa, Liviusynthetic high-porosity sandstone with controlled porosity
Adsorption of small weak organic acids on goethite: Modeling of mechanisms
Filius, J.D.; Hiemstra, T.; Riemsdijk, W.H. Van
1997-11-15
The adsorption of lactate, oxalate, malonate, phthalate, and citrate has been determined experimentally as a function of concentration, pH, and ionic strength. The data have been described with the CD-MUSIC model of Hiemstra and Van Riemsdijk which allows a distribution of charge of the organic molecule over the surface and the Stern layer. Simultaneously, the concentration, pH, and salt dependency as well as the basic charging behavior of goethite could be described well. On the basis of model calculations, a distinction is made between inner and outer sphere complexation of weak organic acids by goethite. The results indicate that the affinity of the organic acids is dominated by the electrostatic attraction. The intrinsic affinity constants for the exchange reaction of surface water groups and organic acids, expressed per bond, increases with increasing number of reactive groups on the organic molecule. Ion pair formation between noncoordinated carboxylic groups of adsorbed organic acids and cations of the background electrolyte proved to be important for the salt dependency. The knowledge obtained may contribute to the interpretation of the binding of larger organic acids like fulvic and humic acids.
Design of Bcl-2 and Bcl-xL Inhibitors with Subnanomolar Binding Affinities Based upon a New Scaffold
Zhou, Haibin; Chen, Jianfang; Meagher, Jennifer L.; Yang, Chao-Yie; Aguilar, Angelo; Liu, Liu; Bai, Longchuan; Cong, Xin; Cai, Qian; Fang, Xueliang; Stuckey, Jeanne A.; Wang, Shaomeng
2014-10-02
Employing a structure-based strategy, we have designed a new class of potent small-molecule inhibitors of the anti-apoptotic proteins Bcl-2 and Bcl-xL. An initial lead compound with a new scaffold was designed based upon the crystal structure of Bcl-xL and U.S. Food and Drug Administration (FDA) approved drugs and was found to have an affinity of 100 {micro}M for both Bcl-2 and Bcl-xL. Linking this weak lead to another weak-affinity fragment derived from Abbott's ABT-737 led to an improvement of the binding affinity by a factor of >10,000. Further optimization ultimately yielded compounds with subnanomolar binding affinities for both Bcl-2 and Bcl-xL and potent cellular activity. The best compound (21) binds to Bcl-xL and Bcl-2 with K{sub i} < 1 nM, inhibits cell growth in the H146 and H1417 small-cell lung cancer cell lines with IC{sub 50} values of 60-90 nM, and induces robust cell death in the H146 cancer cell line at 30-100 nM.
Binding Energies in Nonrelativistic Field Theories
Andreas S. Kronfeld
1996-08-26
Relativistic corrections communicate the binding energy of a bound state to its kinetic mass. This mechanism is reviewed and used to explain anomalous results of Collins, Edwards, Heller, and Sloan (hep-lat/9512026), which compared rest and kinetic masses of heavy-light mesons and quarkonia.
Nucleic acids encoding a cellulose binding domain
Shoseyov, O.; Shpiegl, I.; Goldstein, M.A.; Doi, R.H.
1996-03-05
A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques. 15 figs.
BOUND SYSTEMS 4.A Binding Energy
Boal, David
CHAPTER 4 BOUND SYSTEMS 4.A Binding Energy The mass-energy equation (3.2) is valid for a single linear momentum and its energy. While we introduced the equation in order to describe the energy is measurable. The implication of (4.1) taken with (3.2) is that the mass energy of a bound state is less than
Nucleic acids encoding a cellulose binding domain
Shoseyov, Oded (Karmey Yosef, IL); Shpiegl, Itai (Rehovot, IL); Goldstein, Marc A. (Davis, CA); Doi, Roy H. (Davis, CA)
1996-01-01
A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production thereof. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques.
Homotopy Theory of Strong and Weak Topological Insulators
Ricardo Kennedy; Charles Guggenheim
2014-09-08
We use homotopy theory to extend the notion of strong and weak topological insulators to the non-stable regime (low numbers of occupied/empty energy bands). We show that for strong topological insulators in d spatial dimensions to be "truly d-dimensional", i.e. not realizable by stacking lower-dimensional insulators, a more restrictive definition of "strong" is required. However, this does not exclude weak topological insulators from being "truly d-dimensional", which we demonstrate by an example. Additionally, we prove some useful technical results, including the homotopy theoretic derivation of the factorization of invariants over the torus into invariants over spheres in the stable regime, as well as the rigorous justification of replacing $T^d$ by $S^d$ and $T^{d_k}\\times S^{d_x}$ by $S^{d_k+d_x}$ as is common in the current literature.
Nonlocal resonances in weak turbulence of gravity-capillary waves
Quentin Aubourg; Nicolas Mordant
2015-03-13
We report a laboratory investigation of weak turbulence of water surface waves in the gravity-capillary crossover. By using time-space resolved profilometry and a bicoherence analysis, we observe that the nonlinear processes involve 3-wave resonant interactions. By studying the solutions of the resonance conditions we show that the nonlinear interaction is dominantly 1D and involves collinear wave vectors. Furthermore taking into account the spectral widening due to weak nonlinearity explains that nonlocal interactions are possible between a gravity wave and high frequency capillary ones. We observe also that nonlinear 3-wave coupling is possible among gravity waves and we raise the question of the relevance of this mechanism for oceanic waves.
"Weak Quantum Chaos" and its resistor network modeling
Alexander Stotland; Louis M. Pecora; Doron Cohen
2011-04-29
Weakly chaotic or weakly interacting systems have a wide regime where the common random matrix theory modeling does not apply. As an example we consider cold atoms in a nearly integrable optical billiard with displaceable wall ("piston"). The motion is completely chaotic but with small Lyapunov exponent. The Hamiltonian matrix does not look like one taken from a Gaussian ensemble, but rather it is very sparse and textured. This can be characterized by parameters $s$ and $g$ that reflect the percentage of large elements, and their connectivity, respectively. For $g$ we use a resistor network calculation that has a direct relation to the semi-linear response characteristics of the system, hence leading to a novel prediction regarding the rate of heating of cold atoms in optical billiards with vibrating walls.
Isospin violation and the proton's neutral weak magnetic form factor
Randy Lewis; Nader Mobed
1998-10-05
The effects of isospin violation on the neutral weak magnetic form factor of the proton are studied using two-flavour chiral perturbation theory. The first nonzero contributions appear at O(p^4) in the small-momentum expansion, and the O(p^5) corrections are also calculated. The leading contributions from an explicit Delta(1232) isomultiplet are included as well. At such a high order in the chiral expansion, one might have expected a large number of unknown parameters to contribute. However, it is found that no unknown parameters can appear within loop diagrams, and a single tree-level counterterm at O(p^4) is sufficient to absorb all divergences. The momentum dependence of the neutral weak magnetic form factor is not affected by this counterterm.
The cause of the weak solar cycle 24
Jiang, Jie; Schuessler, Manfred
2015-01-01
The ongoing 11-year cycle of solar activity is considerably less vigorous than the three cycles before. It was preceded by a very deep activity minimum with a low polar magnetic flux, the source of the toroidal field responsible for solar magnetic activity in the subsequent cycle. Simulation of the evolution of the solar surface field shows that the weak polar fields and thus the weakness of the present cycle 24 are mainly caused by a number of bigger bipolar regions emerging at low latitudes with a `wrong' (i.e., opposite to the majority for this cycle) orientation of their magnetic polarities in the North-South direction, which impaired the growth of the polar field. These regions had a particularly strong effect since they emerged within $\\pm10^\\circ$ latitude from the solar equator.
Sensitivity studies for the weak r process: neutron capture rates
Surman, R., E-mail: surmanr@union.edu [Department of Physics and Astronomy, Union College, Schenectady, NY 12308 (United States); Mumpower, M. [Department of Physics, University of Notre Dame, Notre Dame, IN 46556 (United States)] [Department of Physics, University of Notre Dame, Notre Dame, IN 46556 (United States); Sinclair, R.; Jones, K. L. [Department of Physics and Astronomy, University of Tennessee, Knoxville, TN 37996 (United States)] [Department of Physics and Astronomy, University of Tennessee, Knoxville, TN 37996 (United States); Hix, W. R. [Department of Physics and Astronomy, University of Tennessee, Knoxville, TN 37996 (United States) [Department of Physics and Astronomy, University of Tennessee, Knoxville, TN 37996 (United States); Physics Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831 (United States); McLaughlin, G. C. [Department of Physics, North Carolina State University, Raleigh, NC 27695 (United States)] [Department of Physics, North Carolina State University, Raleigh, NC 27695 (United States)
2014-04-15
Rapid neutron capture nucleosynthesis involves thousands of nuclear species far from stability, whose nuclear properties need to be understood in order to accurately predict nucleosynthetic outcomes. Recently sensitivity studies have provided a deeper understanding of how the r process proceeds and have identified pieces of nuclear data of interest for further experimental or theoretical study. A key result of these studies has been to point out the importance of individual neutron capture rates in setting the final r-process abundance pattern for a ‘main’ (A ? 130 peak and above) r process. Here we examine neutron capture in the context of a ‘weak’ r process that forms primarily the A ? 80 r-process abundance peak. We identify the astrophysical conditions required to produce this peak region through weak r-processing and point out the neutron capture rates that most strongly influence the final abundance pattern.
Reduced Generalization in Autism: An Alternative to Weak Central Coherence
Plaisted, Kate C.
2015-06-24
Generalization in Autism: An Alternative to Weak Central Coherence Kate C. Plaisted This chapter appeared in: “The development of Autism: Perspectives from Theory and Research” (2001) Eds :Jacob A. Burack, Tony Charman... , Nurit Yirmiya & Philip R. Zelazo Lawrence Erlbaum Associates, Inc, Publishers. (p 149-169) KC Plaisted-Grant 2015 It has long been observed that individuals with autism exhibit peculiar attentional and perceptual abnormalities...
Weakly Turbulent Magnetohydrodynamic Waves in Compressible Low-{beta} Plasmas
Chandran, Benjamin D. G.
2008-12-05
In this Letter, weak-turbulence theory is used to investigate interactions among Alfven waves and fast and slow magnetosonic waves in collisionless low-{beta} plasmas. The wave kinetic equations are derived from the equations of magnetohydrodynamics, and extra terms are then added to model collisionless damping. These equations are used to provide a quantitative description of a variety of nonlinear processes, including parallel and perpendicular energy cascade, energy transfer between wave types, 'phase mixing', and the generation of backscattered Alfven waves.
Exploration of photon-number entangled states using weak nonlinearities
Yingqiu He; Dong Ding; Fengli Yan; Ting Gao
2015-04-03
A method for exploring photon-number entangled states with weak nonlinearities is described. We show that it is possible to create and detect such entanglement at various scales, ranging from microscopic to macroscopic systems. In the present architecture, we suggest that the maximal phase shift induced in the process of interaction between photons is proportional to photon numbers. Also, in the absence of decoherence we analyze maximum error probability and show its feasibility with current technology.
Unambiguous discrimination of extremely similar states by a weak measurement
Chang Qiao; Shengjun Wu; Zeng-Bing Chen
2013-02-25
In this paper, we propose a method to discriminate two extremely similar quantum states via a weak measurement. For the two states with equal prior probabilities, the optimum discrimination probability given by Ivanovic-Dieks-Peres limit can be achieved by our protocol with an appropriate choice of the interaction strength. However, compared with the conventional method for state discrimination, our approach shows the advantage of error-tolerance by achieving a better ratio of the success probability to the probability of error.
Effective Supergravity from the Weakly Coupled HeteroticString
Gaillard, Mary K.
2005-05-01
The motivation for Calabi-Yau-like compactifications of the weakly coupled E{sub 8} {circle_times} E{sub 8} heterotic string theory, its particle spectrum and the issue of dilaton stabilization are briefly reviewed. Modular invariant models for hidden sector condensation and supersymmetry breaking are described at the quantum level of the effective field theory. Their phenomenological and cosmological implications, including a possible origin for R-parity, are discussed.
Torsion-balance tests of the weak equivalence principle
T. A. Wagner; S. Schlamminger; J. H. Gundlach; E. G. Adelberger
2012-07-10
We briefly summarize motivations for testing the weak equivalence principle and then review recent torsion-balance results that compare the differential accelerations of beryllium-aluminum and beryllium-titanium test body pairs with precisions at the part in $10^{13}$ level. We discuss some implications of these results for the gravitational properties of antimatter and dark matter, and speculate about the prospects for further improvements in experimental sensitivity.
Subsets of superstable structures are weakly benign Bektur Baizhanov
Baldwin, John T.
! x! and R denote {0, 1}. Define E(x, y, 0) to hold if the first coordinates of* * x and y are the same and E(x, y, 1) to hold if the second coordinates of x and y are the same. * *Let A consist Th (M) is stable, fails to be weakly benign. Fix (M, A), a ~+ -saturated of a s* *table theory
Weakly screened thermonuclear reactions in astrophysical plasmas: Improving Salpeter's model
Theodore E. Liolios
2003-06-23
This paper presents a detailed study of the electron degeneracy and nonlinear screening effects which play a crucial role in the validity of Salpeter's weak-screening model. The limitations of that model are investigated and an improved one is proposed which can take into account nonlinear screening effects. Its application to the solar pp reaction derives an accurate screening enhancement factor and provides a very reliable estimation of the associated neutrino flux uncertanties.
Weak Equivalence Principle, Lorentz Non-invariance, and Nuclear Decays
E. Fischbach; V. E. Barnes; J. M. Heim; D. E. Krause; J. M. Nistor
2015-05-16
We consider three possible manifestations of physics beyond the Standard Model, and the relations among them. These are Lorentz non-invariance (LNI), violations of the Weak Equivalence Principle (WEP), and indications of time-varying nuclear decay constants. We present preliminary results from a new experiment indicating the presence of annual and subannual periodicities in decay data, and discuss their implications for physics beyond the Standard Model.
Entrainment of Weakly Coupled Oscillators by External Driving
Anlage, Steven
Entrainment of Weakly Coupled Oscillators by External Driving Rose Faghih and John Platig Advisers entrainment? Entrainment: The response of the oscillator system varies periodically at the period of the drive is a threshold for entrainment. Our Result 0 0.5 1 1.5 2 2.5 3 0 0.5 1 1.5 2 2.5 3 M Entrainment Threshold in M
Universality and scaling limit of weakly-bound tetramers
M. R. Hadizadeh; M. T. Yamashita; Lauro Tomio; A. Delfino; T. Frederico
2011-01-02
The occurrence of a new limit cycle in few-body physics, expressing a universal scaling function relating the binding energies of two consecutive tetramer states, is revealed, considering a renormalized zero-range two-body interaction applied to four identical bosons. The tetramer energy spectrum is obtained when adding a boson to an Efimov bound state with energy $B_3$ in the unitary limit (for zero two-body binding, or infinite two-body scattering length). Each excited $N-$th tetramer energy $B_4^{(N)}$ is shown to slide along a scaling function as a short-range four-body scale is changed, emerging from the 3+1 threshold for a universal ratio $B_4^ {(N)}/B_3 \\simeq 4.6$, which does not depend on $N$. The new scale can also be revealed by a resonance in the atom-trimer recombination process.
Universality and scaling limit of weakly-bound tetramers
Hadizadeh, M R; Tomio, Lauro; Delfino, A; Frederico, T
2011-01-01
The occurrence of a new limit cycle in few-body physics, expressing a universal scaling function relating the binding energies of two consecutive tetramer states, is revealed, considering a renormalized zero-range two-body interaction applied to four identical bosons. The tetramer energy spectrum is obtained when adding a boson to an Efimov bound state with energy $B_3$ in the unitary limit (for zero two-body binding, or infinite two-body scattering length). Each excited $N-$th tetramer energy $B_4^{(N)}$ is shown to slide along a scaling function as a short-range four-body scale is changed, emerging from the 3+1 threshold for a universal ratio $B_4^ {(N)}/B_3 \\simeq 4.6$, which does not depend on $N$. The new scale can also be revealed by a resonance in the atom-trimer recombination process.
Approximations of very weak solutions to boundary-value problems.
Berggren, Martin Olof
2003-03-01
Standard weak solutions to the Poisson problem on a bounded domain have square-integrable derivatives, which limits the admissible regularity of inhomogeneous data. The concept of solution may be further weakened in order to define solutions when data is rough, such as for inhomogeneous Dirichlet data that is only square-integrable over the boundary. Such very weak solutions satisfy a nonstandard variational form (u, v) = G(v). A Galerkin approximation combined with an approximation of the right-hand side G defines a finite-element approximation of the very weak solution. Applying conforming linear elements leads to a discrete solution equivalent to the text-book finite-element solution to the Poisson problem in which the boundary data is approximated by L{sub 2}-projections. The L{sub 2} convergence rate of the discrete solution is O(h{sub s}) for some s {element_of} (0,1/2) that depends on the shape of the domain, asserting a polygonal (two-dimensional) or polyhedral (three-dimensional) domain without slits and (only) square-integrable boundary data.
Collective transport of weakly interacting molecular motors with Langmuir kinetics
Sameep Chandel; Abhishek Chaudhuri; Sudipto Muhuri
2015-01-09
Filament based intracellular transport involves the collective action of molecular motor proteins. Experimental evidences suggest that microtubule (MT) filament bound motor proteins such as {\\it kinesins} weakly interact among themselves during transport and with the surrounding cellular environment. Motivated by these observations we study a driven lattice gas model for collective unidirectional transport of molecular motors on open filament, which incorporates the short-range interactions between the motors on filaments and couples the transport process on filament with surrounding cellular environment through adsorption-desorption Langmuir (LK) kinetics of the motors. We analyse this model within the framework of a Mean Field (MF) theory in the limit of {\\it weak} interactions between the motors. We point to the mapping of this model with the non-conserved version of Katz-Lebowitz-Spohn (KLS) model. The system exhibits rich phase behavior with variety of inhomogeneous phases including localized shocks in the bulk of the filament. We obtain the steady state density and current profiles and analyse their variation as function of the strength of interaction. We compare these MF results with Monte Carlo simulations and find that the MF analysis shows reasonably good agreement as long as the motors are weakly interacting. We also construct the non-equilibrium MF phase diagram.
Catastrophic photometric redshift errors: Weak-lensing survey requirements
DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)
Bernstein, Gary; Huterer, Dragan
2010-01-11
We study the sensitivity of weak lensing surveys to the effects of catastrophic redshift errors - cases where the true redshift is misestimated by a significant amount. To compute the biases in cosmological parameters, we adopt an efficient linearized analysis where the redshift errors are directly related to shifts in the weak lensing convergence power spectra. We estimate the number Nspec of unbiased spectroscopic redshifts needed to determine the catastrophic error rate well enough that biases in cosmological parameters are below statistical errors of weak lensing tomography. While the straightforward estimate of Nspec is ~106 we find that using onlymore »the photometric redshifts with z ? 2.5 leads to a drastic reduction in Nspec to ~ 30,000 while negligibly increasing statistical errors in dark energy parameters. Therefore, the size of spectroscopic survey needed to control catastrophic errors is similar to that previously deemed necessary to constrain the core of the zs – zp distribution. We also study the efficacy of the recent proposal to measure redshift errors by cross-correlation between the photo-z and spectroscopic samples. We find that this method requires ~ 10% a priori knowledge of the bias and stochasticity of the outlier population, and is also easily confounded by lensing magnification bias. In conclusion, the cross-correlation method is therefore unlikely to supplant the need for a complete spectroscopic redshift survey of the source population.« less
Efficient Topological Compilation for Weakly-Integral Anyon Model
Alex Bocharov; Xingshan Cui; Vadym Kliuchnikov; Zhenghan Wang
2015-04-13
In a recent series of two research papers Cui, Wang and Hong proposed a class of anyonic models for universal quantum computation based on weakly-integral anyons. While universal set of gates cannot be obtained in this context by anyon braiding alone, designing a certain type of sector charge measurement provides universality. From the mathematical standpoint the underlying unitary bases arising in various versions of the weakly-integral anyonic models are defined over a certain ring of Eisenstein rationals, that has useful number-theoretic properties. In this paper we develop a compilation algorithm to approximate arbitrary $n$-qutrit unitaries with asymptotically efficient circuits over the metaplectic anyon model, the most recent instance of the weakly-integral anyonic class. One flavor of our algorithm produces efficient circuits with upper complexity bound asymptotically in $O(3^{2\\,n} \\, \\log{1/\\varepsilon})$ and entanglement cost that is exponential in $n$. Another flavor of the algorithm produces efficient circuits with upper complexity bound in $O(n\\,3^{2\\,n} \\, \\log{1/\\varepsilon})$ and no additional entanglement cost.
First Determination of the Weak Charge of the Proton
Androic, D; Armstrong, D S; Asaturyan, A; Averett, T; Balewski, J; Beaufait, J; Beminiwattha, R S; Benesch, J; Benmokhtar, F; Birchall, J; Carlini, R D [JLAB; Cates, G D; Cornejo, J C; Covrig, S; Dalton, M M; Davis, C A; Deconinck, W; Diefenbach, J; Dowd, J F; Dunne, J A; Dutta, D; Duvall, W S; Elaasar, M; Falk, W R; Finn, J M; Forest, T; Gaskell, D; Gericke, M T. W.; Grames, J; Gray, V M; Grimm, K; Guo, F; Hoskins, J R; Johnston, K; Jones, D; Jones, M; Jones, R; Kargiantoulakis, M; King, P M; Korkmaz, E; Kowalski, S; Leacock, J; Leckey, J; Lee, A R; Lee, J H; Lee, L; MacEwan, S; Mack, D; Magee, J A; Mahurin, R; Mammei, J; Martin, J W; McHugh, M J; Meekins, D; Mei, J; Michaels, R; Micherdzinska, A; Mkrtchyan, A; Mkrtchyan, H; Morgan, N; Myers, K E; Narayan, A; Ndukum, L Z; Nelyubin, V; van Oers, W T H; Nuruzzaman,; Opper, A K; Page, S A; Pan, J; Paschke, K D; Phillips, S K; Pitt, M L; Poelker, M; Rajotte, J F; Ramsay, W D; Roche, J; Sawatzky, B; Seva, T; Shabestari, M H; Silwal, R; Simicevic, N; Smith, G R; Solvignon, P; Spayde, D T; Subedi, A; Subedi, R; Suleiman, R; Tadevosyan, V; Tobias, W A; Tvaskis, V; Waidyawansa, B; Wang, P; Wells, S P; Wood, S A; Yang, S; Young, R D; Zhamkochyan, S
2013-10-01
The Qweak experiment has measured the parity-violating asymmetry in polarized e-p elastic scattering at Q^2 = 0.025(GeV/c)^2, employing 145 microamps of 89% longitudinally polarized electrons on a 34.4cm long liquid hydrogen target at Jefferson Lab. The results of the experiment's commissioning run are reported here, constituting approximately 4% of the data collected in the experiment. From these initial results the measured asymmetry is A_e_p = -279 +- 35 (statistics) +- 31 (systematics) ppb, which is the smallest and most precise asymmetry ever measured in polarized e-p scattering. The small Q^2 of this experiment has made possible the first determination of the weak charge of the proton, Q^p_W, by incorporating earlier parity-violating electron scattering (PVES) data at higher Q^2 to constrain hadronic corrections. The value of Q^p_W obtained in this way is Q^p_W(PVES) = 0.064 +- 0.012, in good agreement with the Standard Model prediction of Q^p_W(SM) = 0.0710 +- 0.0007. When this result is further combined with the Cs atomic parity violation (APV) measurement, significant constraints on the weak charges of the up and down quarks can also be extracted. That PVES+APV analysis reveals the neutron's weak charge to be Q^n_W(PVES+APV) = -0.975 +- 0.010.
Optimizing weak lensing mass estimates for cluster profile uncertainty
DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)
Gruen, D.; Bernstein, G. M.; Lam, T. Y.; Seitz, S.
2011-09-11
Weak lensing measurements of cluster masses are necessary for calibrating mass-observable relations (MORs) to investigate the growth of structure and the properties of dark energy. However, the measured cluster shear signal varies at fixed mass M200m due to inherent ellipticity of background galaxies, intervening structures along the line of sight, and variations in the cluster structure due to scatter in concentrations, asphericity and substructure. We use N-body simulated halos to derive and evaluate a weak lensing circular aperture mass measurement Map that minimizes the mass estimate variance ap - M200m)2> in the presence of all these forms of variability. Dependingmore »on halo mass and observational conditions, the resulting mass estimator improves on Map filters optimized for circular NFW-profile clusters in the presence of uncorrelated large scale structure (LSS) about as much as the latter improve on an estimator that only minimizes the influence of shape noise. Optimizing for uncorrelated LSS while ignoring the variation of internal cluster structure puts too much weight on the profile near the cores of halos, and under some circumstances can even be worse than not accounting for LSS at all. As a result, we discuss the impact of variability in cluster structure and correlated structures on the design and performance of weak lensing surveys intended to calibrate cluster MORs.« less
Measuring primordial non-Gaussianity through weak lensing peak counts
Laura Marian; Stefan Hilbert; Robert E. Smith; Peter Schneider; Vincent Desjacques
2012-04-18
We explore the possibility of detecting primordial non-Gaussianity of the local type using weak lensing peak counts. We measure the peak abundance in sets of simulated weak lensing maps corresponding to three models f_NL={0, +100, -100}. Using survey specifications similar to those of Euclid and without assuming any knowledge of the lens and source redshifts, we find the peak functions of the non-Gaussian models with f_NL=+-100 to differ by up to 15% from the Gaussian peak function at the high-mass end. For the assumed survey parameters, the probability of fitting an f_NL=0 peak function to the f_NL=+-100 peak functions is less than 0.1%. Assuming the other cosmological parameters known, f_NL can be measured with an error \\Delta f_NL ~ 13. It is therefore possible that future weak lensing surveys like Euclid and LSST may detect primordial non-Gaussianity from the abundance of peak counts, and provide complementary information to that obtained from the cosmic microwave background.
A. Boulbitch
2004-08-25
A model system has been recently developed to study adhesion. It consists of a giant lipid bilayer vesicle with reconstituted lipo-polymers (repellers) as well as with lipo-ligands recognized by receptors covering the substrate. Adhesion in this system is studied theoretically. The state of the weak adhesion is shown to be dominated by the competition of the gravitation and the undulation repulsion between the membrane and the substrate. The state of the tight adhesion is formed by a competition of the ligand-receptor binding and the lateral osmotic pressure of the mobile repeller molecules. The regions of the weak and the tight adhesion are separated on the phase diagram by a whole transition region due to the scattering in parameters of vesicles.
Study of fragmentation using clusterization algorithm with realistic binding energies
Yogesh K. Vermani; Jatinder K. Dhawan; Supriya Goyal; Rajeev K. Puri; J. Aichelin
2009-12-28
We here study fragmentation using \\emph{simulated annealing clusterization algorithm} (SACA) with binding energy at a microscopic level. In an earlier version, a constant binding energy (4 MeV/nucleon) was used. We improve this binding energy criterion by calculating the binding energy of different clusters using modified Bethe-Weizs\\"{a}cker mass (BWM) formula. We also compare our calculations with experimental data of ALADiN group. Nearly no effect is visible of this modification.
Predicting Metal-Binding Sites from Protein Sequence
Passerini, Andrea
Predicting Metal-Binding Sites from Protein Sequence Andrea Passerini, Marco Lippi, and Paolo algorithmic ideas based on structured- output learning for determining transition-metal-binding sites coordinate more than one metal ion, we prove that metal binding has the algebraic structure of a matroid
Ferrate(VI) oxidation of weak-acid dissociable cyanides
Ria A. Yngard; Virender K. Sharma; Jan Filip; Radek Zboril [Florida Institute of Technology, Melbourne, FL (United States). Chemistry Department, Florida Institute of Technology
2008-04-15
Cyanide is commonly found in electroplating, mining, coal gasification, and petroleum refining effluents, which require treatment before being discharged. Cyanide in effluents exists either as free cyanide or as a metal complex. The kinetics of the oxidation of weak-acid dissociable cyanides by an environmentally friendly oxidant, ferrate, were studied as a function of pH (9.1-10.5) and temperature (15-45{sup o}C) using a stopped-flow technique. The weak-acid dissociable cyanides were Cd(CN){sub 4}{sup 2-} and Ni(CN){sub 4}{sup 2-}, and the rate-laws for the oxidation may be -d(Fe(VI))/dt = k (Fe(VI))(M(CN){sub 4}{sup 2-}){sup n} where n = 0.5 and 1 for Cd(CN){sub 4}{sup 2-} and Ni(CN){sub 4}{sup 2-}, respectively. The rates decreased with increasing pH and were mostly related to a decrease in concentration of the reactive protonated Fe(VI) species, HFeO{sub 4}{sup -}. The stoichiometries with Fe(VI) were determined to be: 4HFeO{sub 4}{sup -} + M(CN){sub 4}{sup 2-} + 6H{sub 2}O {yields} 4Fe(OH){sub 3} + M{sup 2+} + 4NCO{sup -} + O{sub 2} + 4OH{sup -}. Mechanisms are proposed that agree with the observed reaction rate-laws and stoichiometries of the oxidation of weak-acid dissociable cyanides by Fe(VI). Results indicate that Fe(VI) is effective in removing cyanide in coke oven plant effluent, where organics are also present. 27 refs., 3 figs., 2 tabs.
Optimal generation of Fock states in a weakly nonlinear oscillator
B. Khani; J. M. Gambetta; F. Motzoi; F. K. Wilhelm
2009-09-25
We apply optimal control theory to determine the shortest time in which an energy eigenstate of a weakly anharmonic oscillator can be created under the practical constraint of linear driving. We show that the optimal pulses are beatings of mostly the transition frequencies for the transitions up to the desired state and the next leakage level. The time of a shortest possible pulse for a given nonlinearity scale with the nonlinearity parameter delta as a power law of alpha with alpha=-0.73 +/-0.029. This is a qualitative improvement relative to the value alpha=1 suggested by a simple Landau-Zener argument.
Semiclassical suppression of weak anisotropies of a generic Universe
Marco Valerio Battisti; Riccardo Belvedere; Giovanni Montani
2009-06-11
A semiclassical mechanism which suppresses the weak anisotropies of an inhomogeneous cosmological model is developed. In particular, a wave function of this Universe having a meaningful probabilistic interpretation is obtained that is in agreement with the Copenhagen School. It describes the evolution of the anisotropies with respect to the isotropic scale factor which is regarded as a semiclassical variable playing an observer-like role. Near the cosmological singularity the solution spreads over all values of the anisotropies while, when the Universe expands sufficiently, the closed Friedmann-Robertson-Walker model appears to be the favorite state.
Utilizing weak pump depletion to stabilize squeezed vacuum states
Timo Denker; Dirk Schütte; Maximilian H. Wimmer; Trevor A. Wheatley; Elanor H. Huntington; Michèle Heurs
2015-03-10
We propose and demonstrate a pump-phase locking technique that makes use of weak pump depletion (WPD) - an unavoidable effect that is usually neglected - in a sub-threshold optical parametric oscillator (OPO). We show that the phase difference between seed and pump beam is imprinted on both light fields by the non-linear interaction in the crystal and can be read out without disturbing the squeezed output. Our new locking technique allows for the first experimental realization of a pump-phase lock by reading out the pre-existing phase information in the pump field. There is no degradation of the detected squeezed states required to implement this scheme.
Dark-Matter-Induced Violation of the Weak Equivalence Principle
Carroll, Sean M.; Mantry, Sonny [California Institute of Technology, Pasadena, California 91125 (United States); Ramsey-Musolf, Michael J. [University of Wisconsin-Madison, Madison, Wisconsin 53706 (United States); California Institute of Technology, Pasadena, California 91125 (United States); Stubbs, Christoper W. [Harvard-Smithsonian Center for Astrophysics, Cambridge, Massachusetts 02138 (United States)
2009-07-03
A long-range fifth force coupled to dark matter can induce a coupling to ordinary matter if the dark matter interacts with standard model fields. We consider constraints on such a scenario from both astrophysical observations and laboratory experiments. We also examine the case where the dark matter is a weakly interacting massive particle, and derive relations between the coupling to dark matter and the coupling to ordinary matter for different models. Currently, this scenario is most tightly constrained by galactic dynamics, but improvements in Eoetvoes experiments can probe unconstrained regions of parameter space.
Linear and nonlinear wave propagation in weakly relativistic quantum plasmas
Stefan, Martin; Brodin, Gert [Department of Physics, Umea University, SE-901 87 Umea (Sweden)
2013-01-15
We consider a recently derived kinetic model for weakly relativistic quantum plasmas. We find that that the effects of spin-orbit interaction and Thomas precession may alter the linear dispersion relation for a magnetized plasma in case of high plasma densities and/or strong magnetic fields. Furthermore, the ponderomotive force induced by an electromagnetic pulse is studied for an unmagnetized plasma. It turns out that for this case the spin-orbit interaction always gives a significant contribution to the quantum part of the ponderomotive force.
Optimal waveform for the entrainment of a weakly forced oscillator
Takahiro Harada; Hisa-Aki Tanaka; Michael J. Hankins; István Z. Kiss
2010-07-24
A theory for obtaining waveform for the effective entrainment of a weakly forced oscillator is presented. Phase model analysis is combined with calculus of variation to derive a waveform with which entrainment of an oscillator is achieved with minimum power forcing signal. Optimal waveforms are calculated from the phase response curve and a solution to a balancing condition. The theory is tested in chemical entrainment experiments in which oscillations close to and further away from a Hopf bifurcation exhibited sinusoidal and higher harmonic nontrivial optimal waveforms, respectively.
HISTORY OF WEAK INTERACTIONS. (Technical Report) | SciTech Connect
Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverse (Journalvivo Low-Dose Lowï‚— WeUpdateScienceForTripHISTORY OF WEAK
Evidence for a Weak Iron Core at Earth's Center
Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansasCommunitiesof Energy8) Wigner Home Â·theEvenEvidence for a Weak Iron
Evidence for a Weak Iron Core at Earth's Center
Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansasCommunitiesof Energy8) Wigner Home Â·theEvenEvidence for a Weak
Dual chain synthetic heparin-binding growth factor analogs
Zamora, Paul O. (Gaithersburg, MD); Pena, Louis A. (Poquott, NY); Lin, Xinhua (Plainview, NY)
2012-04-24
The invention provides synthetic heparin-binding growth factor analogs having two peptide chains each branched from a branch moiety, such as trifunctional amino acid residues, the branch moieties separated by a first linker of from 3 to about 20 backbone atoms, which peptide chains bind a heparin-binding growth factor receptor and are covalently bound to a non-signaling peptide that includes a heparin-binding domain, preferably by a second linker, which may be a hydrophobic second linker. The synthetic heparin-binding growth factor analogs are useful as pharmaceutical agents, soluble biologics or as surface coatings for medical devices.
Dual chain synthetic heparin-binding growth factor analogs
Zamora, Paul O. (Gaithersburg, MD); Pena, Louis A. (Poquott, NY); Lin, Xinhua (Plainview, NY)
2009-10-06
The invention provides synthetic heparin-binding growth factor analogs having two peptide chains each branched from a branch moiety, such as trifunctional amino acid residues, the branch moieties separated by a first linker of from 3 to about 20 backbone atoms, which peptide chains bind a heparin-binding growth factor receptor and are covalently bound to a non-signaling peptide that includes a heparin-binding domain, preferably by a second linker, which may be a hydrophobic second linker. The synthetic heparin-binding growth factor analogs are useful as pharmaceutical agents, soluble biologics or as surface coatings for medical devices.
Dismantlability of weakly systolic complexes and applications Victor Chepoi1 and Damian Osajda2
Osajda, Damian
Dismantlability of weakly systolic complexes and applications Victor Chepoi1 and Damian Osajda2 1 and groups. The fixed point theorem is proved by using a graph-theoretical tool -- dismantlability. In particular we show that 1skeleta of weakly systolic complexes, i.e. weakly bridged graphs, are dismantlable
RESTRICTING THE WEAK-GENERATIVE CAPACITY OF SYNCHRONOUS TREE-ADJOINING GRAMMARS
Shieber, Stuart
RESTRICTING THE WEAK-GENERATIVE CAPACITY OF SYNCHRONOUS TREE-ADJOINING GRAMMARS STUART M. SHIEBER: Synchronous tree-adjoining grammars, weak-generative ca- pacity, machine translation, natural reasons. First, the weak-generative expressivity of TAGs is increased through the synchronization
ON THE SUSTAINABILITY AND ARREST OF WEAK LAYER FRACTURE IN WHUMPFS AND Dave Gauthier*1
Jamieson, Bruce
ON THE SUSTAINABILITY AND ARREST OF WEAK LAYER FRACTURE IN WHUMPFS AND AVALANCHES Dave Gauthier*1, Alberta, Canada ABSTRACT: Recent theoretical and practical descriptions of weak layer fracture have-sustaining. Arrest of weak layer fracture has been addressed for shear-based models, but has often been overlooked
The emergence of weakly twisted magnetic fields in the sun
Archontis, V.; Hood, A. W.; Tsinganos, K.
2013-11-20
We have studied the emergence of a weakly twisted magnetic flux tube from the upper convection zone into the solar atmosphere. It is found that the rising magnetized plasma does not undergo the classical, single ?-shaped loop emergence, but it becomes unstable in two places, forming two magnetic lobes that are anchored in small-scale bipolar structures at the photosphere, between the two main flux concentrations. The two magnetic lobes rise and expand into the corona, forming an overall undulating magnetic flux system. The dynamical interaction of the lobes results in the triggering of high-speed and hot jets and the formation of successive cool and hot loops that coexist in the emerging flux region. Although the initial emerging field is weakly twisted, a highly twisted magnetic flux rope is formed at the low atmosphere, due to shearing and reconnection. The new flux rope (hereafter post-emergence flux rope) does not erupt. It remains confined by the overlying field. Although there is no ejective eruption of the post-emergence rope, it is found that a considerable amount of axial and azimuthal flux is transferred into the solar atmosphere during the emergence of the magnetic field.
Weak chaos, infinite ergodic theory, and anomalous dynamics
Rainer Klages
2015-07-15
This book chapter introduces to the concept of weak chaos, aspects of its ergodic theory description, and properties of the anomalous dynamics associated with it. In the first half of the chapter we study simple one-dimensional deterministic maps, in the second half basic stochastic models and eventually an experiment. We start by reminding the reader of fundamental chaos quantities and their relation to each other, exemplified by the paradigmatic Bernoulli shift. Using the intermittent Pomeau-Manneville map the problem of weak chaos and infinite ergodic theory is outlined, defining a very recent mathematical field of research. Considering a spatially extended version of the Pomeau-Manneville map leads us to the phenomenon of anomalous diffusion. This problem will be discussed by applying stochastic continuous time random walk theory and by deriving a fractional diffusion equation. Another important topic within modern nonequilibrium statistical physics are fluctuation relations, which we investigate for anomalous dynamics. The chapter concludes by showing the importance of anomalous dynamics for understanding experimental results on biological cell migration.
Linearly resummed hydrodynamics in a weakly curved spacetime
Yanyan Bu; Michael Lublinsky
2015-02-27
We extend our study of all-order linearly resummed hydrodynamics in a flat space~\\cite{1406.7222,1409.3095} to fluids in weakly curved spaces. The underlying microscopic theory is a finite temperature $\\mathcal{N}=4$ super-Yang-Mills theory at strong coupling. The AdS/CFT correspondence relates black brane solutions of the Einstein gravity in asymptotically \\emph{locally} $\\textrm{AdS}_5$ geometry to relativistic conformal fluids in a weakly curved 4D background. To linear order in the amplitude of hydrodynamic variables and metric perturbations, the fluid's energy-momentum tensor is computed with derivatives of both the fluid velocity and background metric resummed to all orders. We extensively discuss the meaning of all order hydrodynamics by expressing it in terms of the memory function formalism, which is also suitable for practical simulations. In addition to two viscosity functions discussed at length in refs.~\\cite{1406.7222,1409.3095}, we find four curvature induced structures coupled to the fluid via new transport coefficient functions. In ref.~\\cite{0905.4069}, the latter were referred to as gravitational susceptibilities of the fluid. We analytically compute these coefficients in the hydrodynamic limit, and then numerically up to large values of momenta.
Polynucleotides encoding TRF1 binding proteins
Campisi, Judith (Berkeley, CA); Kim, Sahn-Ho (Albany, CA)
2002-01-01
The present invention provides a novel telomere associated protein (Trf1-interacting nuclear protein 2 "Tin2") that hinders the binding of Trf1 to its specific telomere repeat sequence and mediates the formation of a Tin2-Trf1-telomeric DNA complex that limits telomerase access to the telomere. Also included are the corresponding nucleic acids that encode the Tin2 of the present invention, as well as mutants of Tin2. Methods of making, purifying and using Tin2 of the present invention are described. In addition, drug screening assays to identify drugs that mimic and/or complement the effect of Tin2 are presented.
Connotation Lexicon: A Dash of Sentiment Beneath the Surface Meaning
Anderson, Richard
of sentiment beyond denotative or surface meaning of text. For instance, consider the following: Geothermal toward "geothermal". In order to sense the subtle overtone of sentiments, one needs to know that the word "emissions" has generally negative connota- tion, which geothermal reduces. In fact, depend- ing
Dash for Bikes, Walk for Trikes | National Nuclear Security Administration
National Nuclear Security Administration (NNSA)
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefield Municipal Gas &SCE-SessionsSouthReporteeo | National/%2A en| National Nuclear
Borbulevych, Oleg Y.; Piepenbrink, Kurt H.; Baker, Brian M.
2012-03-16
Molecular mimicry between foreign and self Ags is a mechanism of TCR cross-reactivity and is thought to contribute to the development of autoimmunity. The {alpha}{beta} TCR A6 recognizes the foreign Ag Tax from the human T cell leukemia virus-1 when presented by the class I MHC HLA-A2. In a possible link with the autoimmune disease human T cell leukemia virus-1-associated myelopathy/tropical spastic paraparesis, A6 also recognizes a self peptide from the neuronal protein HuD in the context of HLA-A2. We found in our study that the complexes of the HuD and Tax epitopes with HLA-A2 are close but imperfect structural mimics and that in contrast with other recent structures of TCRs with self Ags, A6 engages the HuD Ag with the same traditional binding mode used to engage Tax. Although peptide and MHC conformational changes are needed for recognition of HuD but not Tax and the difference of a single hydroxyl triggers an altered TCR loop conformation, TCR affinity toward HuD is still within the range believed to result in negative selection. Probing further, we found that the HuD-HLA-A2 complex is only weakly stable. Overall, these findings help clarify how molecular mimicry can drive self/nonself cross-reactivity and illustrate how low peptide-MHC stability can permit the survival of T cells expressing self-reactive TCRs that nonetheless bind with a traditional binding mode.
Simple pulses for elimination of leakage in weakly nonlinear qubits
F. Motzoi; J. M. Gambetta; P. Rebentrost; F. K. Wilhelm
2009-10-22
In realizations of quantum computing, a two-level system (qubit) is often singled out of the many levels of an anharmonic oscillator. In these cases, simple qubit control fails on short time scales because of coupling to leakage levels. We provide an easy to implement analytic formula that inhibits this leakage from any single-control analog or pixelated pulse. It is based on adding a second control that is proportional to the time-derivative of the first. For realistic parameters of superconducting qubits, this strategy reduces the error by an order of magnitude relative to the state of the art, all based on smooth and feasible pulse shapes. These results show that even weak anharmonicity is sufficient and in general not a limiting factor for implementing quantum gates.
PROTOSTELLAR DISK FORMATION ENABLED BY WEAK, MISALIGNED MAGNETIC FIELDS
Krumholz, Mark R.; Crutcher, Richard M.; Hull, Charles L. H.
2013-04-10
The gas from which stars form is magnetized, and strong magnetic fields can efficiently transport angular momentum. Most theoretical models of this phenomenon find that it should prevent formation of large (>100 AU), rotationally supported disks around most protostars, even when non-ideal magnetohydrodynamic (MHD) effects that allow the field and gas to decouple are taken into account. Using recent observations of magnetic field strengths and orientations in protostellar cores, we show that this conclusion is incorrect. The distribution of magnetic field strengths is very broad, and alignments between fields and angular momentum vectors within protostellar cores are essentially random. By combining the field strength and misalignment data with MHD simulations showing that disk formation is expected for both weak and misaligned fields, we show that these observations imply that we should expect disk fractions of {approx}10%-50% even when protostars are still deeply embedded in their parent cores, and even if the gas is governed by ideal MHD.
Absolute Dynamical Limit to Cooling Weakly-Coupled Quantum Systems
X. Wang; Sai Vinjanampathy; Frederick W. Strauch; Kurt Jacobs
2012-05-15
Cooling of a quantum system is limited by the size of the control forces that are available (the "speed" of control). We consider the most general cooling process, albeit restricted to the regime in which the thermodynamics of the system is preserved (weak coupling). Within this regime, we further focus on the most useful control regime, in which a large cooling factor, and good ground-state cooling can be achieved. We present a control protocol for cooling, and give clear structural arguments, as well as strong numerical evidence, that this protocol is globally optimal. From this we obtain simple expressions for the limit to cooling that is imposed by the speed of control.
Continuum discretized BCS approach for weakly bound nuclei
J. A. Lay; C. E. Alonso; L. Fortunato; A. Vitturi
2015-10-12
The Bardeen-Cooper-Schrieffer (BCS) formalism is extended by including the single-particle continuum, thus enabling the analysis of an isotopic chain from stability up to the drip line. We propose a continuum discretized generalized BCS based on single-particle pseudostates (PS). These PS are generated from the diagonalization of the single-particle Hamiltonian within a Transformed Harmonic Oscillator (THO) basis. The consistency of the results versus the size of the basis is studied. The method is applied to neutron rich Oxygen and Carbon isotopes and compared with similar previous works and available experimental data. We make use of the flexibility of the proposed model in order to study the evolution of the occupation of the low-energy continuum when the system becomes weakly bound. We find a larger influence of the non-resonant continuum as long as the Fermi level approaches zero.
Cubic Ideal Ferromagnets at Low Temperature and Weak Magnetic Field
Christoph P. Hofmann
2015-11-10
The low-temperature series for the free energy density, pressure, magnetization and susceptibility of cubic ideal ferromagnets in weak external magnetic fields are discussed within the effective Lagrangian framework up to three loops. The structure of the simple, body-centered, and face-centered cubic lattice is taken into account explicitly. The expansion involves integer and half-integer powers of the temperature. The corresponding coefficients depend on the magnetic field and on low-energy effective constants that can be expressed in terms of microscopic quantities. Our formulas may also serve as efficiency or consistency check for other techniques like Green's function methods, where spurious terms in the low-temperature expansion have appeared. We explore the sign and magnitude of the spin-wave interaction in the pressure, magnetization and susceptibility, and emphasize that our effective field theory approach is fully systematic and rigorous.
Weak-strong clustering transition in renewing compressible flows
Ajinkya Dhanagare; Stefano Musacchio; Dario Vincenzi
2014-11-01
We investigate the statistical properties of Lagrangian tracers transported by a time-correlated compressible renewing flow. We show that the preferential sampling of the phase space performed by tracers yields significant differences between the Lagrangian statistics and its Eulerian counterpart. In particular, the effective compressibility experienced by tracers has a non-trivial dependence on the time correlation of the flow. We examine the consequence of this phenomenon on the clustering of tracers, focusing on the transition from the weak- to the strong-clustering regime. We find that the critical compressibility at which the transition occurs is minimum when the time correlation of the flow is of the order of the typical eddy turnover time. Further, we demonstrate that the clustering properties in time-correlated compressible flows are non-universal and are strongly influenced by the spatio-temporal structure of the velocity field.
Weak-strong clustering transition in renewing compressible flows
Dhanagare, Ajinkya; Vincenzi, Dario
2014-01-01
We investigate the statistical properties of Lagrangian tracers transported by a time-correlated compressible renewing flow. We show that the preferential sampling of the phase space performed by tracers yields significant differences between the Lagrangian statistics and its Eulerian counterpart. In particular, the effective compressibility experienced by tracers has a non-trivial dependence on the time correlation of the flow. We examine the consequence of this phenomenon on the clustering of tracers, focusing on the transition from the weak- to the strong-clustering regime. We find that the critical compressibility at which the transition occurs is minimum when the time correlation of the flow is of the order of the typical eddy turnover time. Further, we demonstrate that the clustering properties in time-correlated compressible flows are non-universal and are strongly influenced by the spatio-temporal structure of the velocity field.
Bremsstrahlung function, leading Luscher correction at weak coupling and localization
Bonini, Marisa; Preti, Michelangelo; Seminara, Domenico
2015-01-01
We discuss the near BPS expansion of the generalized cusp anomalous dimension with L units of R-charge. Integrability provides an exact solution, obtained by solving a general TBA equation in the appropriate limit: we propose here an alternative method based on supersymmetric localization.The basic idea is to relate the computation to the vacuum expectation value of certain 1/8 BPS Wilson loops with local operator insertions along the contour. These observables localize on a two-dimensional gauge theory on S^2, opening the possibility of exact calculations. As a test of our proposal, we reproduce the leading Luscher correction at weak coupling to the generalized cusp anomalous dimension. This result is also checked against a genuine Feynman diagram approach in N=4 Super Yang-Mills theory.
Autoresonance energy transfer versus localization in weakly coupled oscillators
Agnessa Kovaleva; Leonid Manevitch
2014-10-22
In this paper we investigate the distribution of energy between weakly coupled linear and nonlinear oscillators in a two-degree-of-freedom (2D) system. Two classes of problems are studied analytically and numerically: (1) a periodic force with constant frequency is applied to the nonlinear (Duffing) oscillator with slowly time-decreasing linear stiffness; (2) the time-independent nonlinear oscillator is excited by a force with slowly increasing frequency. In both cases, stiffness of the attached linear oscillator and linear coupling remain constant, and the system is initially engaged in resonance. This paper demonstrates that in the systems of the first type autoresonance (AR) occurs in both oscillators while in systems of the second type AR occurs only in the excited nonlinear oscillator but the coupled linear oscillator exhibits small bounded oscillations. Considering slow detuning, we obtain explicit asymptotic approximations for the amplitudes and the phases of oscillations close to exact (numerical) results.
The Weak-Coupling Limit of Simplicial Quantum Gravity
G. Thorleifsson; P. Bialas; B. Petersson
1998-12-23
In the weak-coupling limit, kappa_0 going to infinity, the partition function of simplicial quantum gravity is dominated by an ensemble of triangulations with the ratio N_0/N_D close to the upper kinematic limit. For a combinatorial triangulation of the D--sphere this limit is 1/D. Defining an ensemble of maximal triangulations, i.e. triangulations that have the maximal possible number of vertices for a given volume, we investigate the properties of this ensemble in three dimensions using both Monte Carlo simulations and a strong-coupling expansion of the partition function, both for pure simplicial gravity and a with a suitable modified measure. For the latter we observe a continuous phase transition to a crinkled phase and we investigate the fractal properties of this phase.
Weak Matrix Elements on the Lattice --- Circa 1995
A. Soni
1995-10-20
Status of weak matrix elements is reviewed. In particular, $\\epspeps$, $\\bkastg$, $B_K$, $B_B$ and $B_{B_s}$ are discussed and the overall situation with respect to the lattice effort and some of its phenomenological implications are summarized. For $\\epspeps$ the need for the relevant matrix elements is stressed in view of the forthcoming improved experiments. For some of the operators, (e.g.\\ $O_6$), even bounds on their matrix elements would be very helpful. On $\\bkastg$, a constant behavior of $T_2$ appears disfavored although dependence of $T_2$ could, of course, be milder than a simple pole. Improved data is badly needed to settle this important issue firmly, especially in view of its ramification for extractions of $V_{td}$ from $B\\to\\rho\\gamma$. On $B_K$, the preliminary result from JLQCD appears to contradict Sharpe \\etal\\ JLQCD data seems to fit very well to linear $a$ dependence and leads to an appreciably lower value of $B_K$. Four studies of $B_K$ in the ``full'' ($n_f=2$) theory indicate very little quenching effects on $B_K$; the full theory value seems to be just a little less than the quenched result. Based on expectations from HQET, analysis of the $B$-parameter ($B_{h\\ell}$) for the heavy-light mesons via $B_{h\\ell}={}$constant${}+{}$constants$^\\prime/m_{h\\ell}$ is suggested. A summary of an illustrative sample of hadron matrix elements is given and constraints on CKM parameters (e.g.\\ $V_{td}/V_{ts}$), on the unitarity triangle and on $x_s/x_d$, emerging from the lattice calculations along with experimental results are briefly discussed. In quite a few cases, for the first time, some indication of quenching errors on weak matrix elements are now becoming available.
Hardware device to physical structure binding and authentication
Hamlet, Jason R.; Stein, David J.; Bauer, Todd M.
2013-08-20
Detection and deterrence of device tampering and subversion may be achieved by including a cryptographic fingerprint unit within a hardware device for authenticating a binding of the hardware device and a physical structure. The cryptographic fingerprint unit includes an internal physically unclonable function ("PUF") circuit disposed in or on the hardware device, which generate an internal PUF value. Binding logic is coupled to receive the internal PUF value, as well as an external PUF value associated with the physical structure, and generates a binding PUF value, which represents the binding of the hardware device and the physical structure. The cryptographic fingerprint unit also includes a cryptographic unit that uses the binding PUF value to allow a challenger to authenticate the binding.
Crown Ethers Flatten in Graphene for Strong, Specific Binding...
Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)
2011 2010 News Home | ORNL | News | Features | 2014 SHARE Crown Ethers Flatten in Graphene for Strong, Specific Binding ORNL discovery holds potential for separations, sensors,...
Neptunium Binding Kinetics with Arsenazo(III)
Leigh R. Martin; Aaron T. Johnson; Stephen P. Mezyk
2014-08-01
This document has been prepared to meet FCR&D level 2 milestone M2FT-14IN0304021, “Report on the results of actinide binding kinetics with aqueous phase complexants” This work was carried out under the auspices of the Thermodynamics and Kinetics of Advanced Separations Systems FCR&D work package. The report details kinetics experiments that were performed to measure rates of aqueous phase complexation for pentavalent neptunium with the chromotropic dye Arsenazo III (AAIII). The studies performed were designed to determine how pH, ionic strength and AAIII concentration may affect the rate of the reaction. A brief comparison with hexavalent neptunium is also made. It was identified that as pH was increased the rate of reaction also increased, however increasing the ionic strength and concentration of AAIII had the opposite effect. Interestingly, the rate of reaction of Np(VI) with AAIII was found to be slower than that of the Np(V) reaction.
Chinchilla, Diana, E-mail: Diana_Chinchilla@yahoo.com; Kilheeney, Heather, E-mail: raindropszoo@yahoo.com; Vitello, Lidia B., E-mail: lvitello@niu.edu; Erman, James E., E-mail: jerman@niu.edu
2014-01-03
Highlights: •Cytochrome c peroxidase (CcP) binds acrylonitrile in a pH-independent fashion. •The spectrum of the CcP/acrylonitrile complex is that of a 6c–ls ferric heme. •The acrylonitrile/CcP complex has a K{sub D} value of 1.1 ± 0.2 M. •CcP compound I oxidizes acrylonitrile with a maximum turnover rate of 0.61 min{sup ?1}. -- Abstract: Ferric heme proteins bind weakly basic ligands and the binding affinity is often pH dependent due to protonation of the ligand as well as the protein. In an effort to find a small, neutral ligand without significant acid/base properties to probe ligand binding reactions in ferric heme proteins we were led to consider the organonitriles. Although organonitriles are known to bind to transition metals, we have been unable to find any prior studies of nitrile binding to heme proteins. In this communication we report on the equilibrium and kinetic properties of acrylonitrile binding to cytochrome c peroxidase (CcP) as well as the oxidation of acrylonitrile by CcP compound I. Acrylonitrile binding to CcP is independent of pH between pH 4 and 8. The association and dissociation rate constants are 0.32 ± 0.16 M{sup ?1} s{sup ?1} and 0.34 ± 0.15 s{sup ?1}, respectively, and the independently measured equilibrium dissociation constant for the complex is 1.1 ± 0.2 M. We have demonstrated for the first time that acrylonitrile can bind to a ferric heme protein. The binding mechanism appears to be a simple, one-step association of the ligand with the heme iron. We have also demonstrated that CcP can catalyze the oxidation of acrylonitrile, most likely to 2-cyanoethylene oxide in a “peroxygenase”-type reaction, with rates that are similar to rat liver microsomal cytochrome P450-catalyzed oxidation of acrylonitrile in the monooxygenase reaction. CcP compound I oxidizes acrylonitrile with a maximum turnover number of 0.61 min{sup ?1} at pH 6.0.
Photoexcited energy transfer in a weakly coupled dimer
DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)
Hernandez, Laura Alfonso; Nelson, Tammie; Tretiak, Sergei; Fernandez-Alberti, Sebastian
2015-01-08
Nonadiabatic excited-state molecular dynamics (NA-ESMD) simulations have been performed in order to study the time-dependent exciton localization during energy transfer between two chromophore units of the weakly coupled anthracene dimer dithia-anthracenophane (DTA). Simulations are done at both low temperature (10 K) and room temperature (300 K). The initial photoexcitation creates an exciton which is primarily localized on a single monomer unit. Subsequently, the exciton experiences an ultrafast energy transfer becoming localized on either one monomer unit or the other, whereas delocalization between both monomers never occurs. In half of the trajectories, the electronic transition density becomes completely localized on themore »same monomer as the initial excitation, while in the other half, it becomes completely localized on the opposite monomer. In this article, we present an analysis of the energy transfer dynamics and the effect of thermally induced geometry distortions on the exciton localization. Finally, simulated fluorescence anisotropy decay curves for both DTA and the monomer unit dimethyl anthracene (DMA) are compared. As a result, our analysis reveals that changes in the transition density localization caused by energy transfer between two monomers in DTA is not the only source of depolarization and exciton relaxation within a single DTA monomer unit can also cause reorientation of the transition dipole.« less
Wormholes, Emergent Gauge Fields, and the Weak Gravity Conjecture
Harlow, Daniel
2015-01-01
This paper revisits the question of reconstructing bulk gauge fields as boundary operators in AdS/CFT. In the presence of the wormhole dual to the thermofield double state of two CFTs, the existence of bulk gauge fields is in some tension with the microscopic tensor factorization of the Hilbert space. I explain how this tension can be resolved by splitting the gauge field into charged constituents, and I argue that this leads to a new argument for the "principle of completeness", which states that the charge lattice of a gauge theory coupled to gravity must be fully populated. I also claim that it leads to a new motivation for (and a clarification of) the "weak gravity conjecture", which I interpret as a strengthening of this principle. This setup gives a simple example of a situation where describing low-energy bulk physics in CFT language requires knowledge of high-energy bulk physics. This contradicts to some extent the notion of "effective conformal field theory", but in fact is an expected feature of the...
Weak lensing by galaxy troughs in DES Science Verification data
Gruen, D; Amara, A; Bacon, D; Bonnett, C; Hartley, W; Jain, B; Jarvis, M; Kacprzak, T; Krause, E; Mana, A; Rozo, E; Rykoff, E S; Seitz, S; Sheldon, E; Troxel, M A; Vikram, V; Abbott, T; Abdalla, F B; Allam, S; Armstrong, R; Banerji, M; Bauer, A H; Becker, M R; Benoit-Levy, A; Bernstein, G M; Bernstein, R A; Bertin, E; Bridle, S L; Brooks, D; Buckley-Geer, E; Burke, D L; Capozzi, D; Rosell, A Carnero; Kind, M Carrasco; Carretero, J; Crocce, M; Cunha, C E; D'Andrea, C B; da Costa, L N; DePoy, D L; Desai, S; Diehl, H T; Dietrich, J P; Doel, P; Eifler, T F; Neto, A Fausti; Fernandez, E; Flaugher, B; Fosalba, P; Frieman, J; Gerdes, D W; Gruendl, R A; Gutierrez, G; Honscheid, K; James, D J; Kuehn, K; Kuropatkin, N; Lahav, O; Li, T S; Lima, M; Maia, M A G; March, M; Martini, P; Melchior, P; Miller, C J; Miquel, R; Mohr, J J; Nord, B; Ogando, R; Plazas, A A; Reil, K; Romer, A K; Roodman, A; Sako, M; Sanchez, E; Scarpine, V; Schubnell, M; Sevilla-Noarbe, I; Smith, R C; Soares-Santos, M; Sobreira, F; Suchyta, E; Swanson, M E C; Tarle, G; Thaler, J; Thomas, D; Walker, A R; Wechsler, R H; Weller, J; Zhang, Y; Zuntz, J
2015-01-01
We measure the weak lensing shear around galaxy troughs, i.e. the radial alignment of background galaxies relative to underdensities in projections of the foreground galaxy field over a wide range of redshift in Science Verification data from the Dark Energy Survey. Our detection of the shear signal is highly significant (10 to 15sigma for the smallest angular scales) for troughs with the redshift range z in [0.2,0.5] of the projected galaxy field and angular diameters of 10'...1{\\deg}. These measurements probe the connection between the galaxy, matter density, and convergence fields. By assuming galaxies are biased tracers of the matter density with Poissonian noise, we find agreement of our measurements with predictions in a fiducial LambdaCDM model. The prediction for the lensing signal on large trough scales is virtually independent of the details of the underlying model for the connection of galaxies and matter. Our comparison of the shear around troughs with that around cylinders with large galaxy count...
The effect of weak lensing on distance estimates from supernovae
Smith, Mathew; Maartens, Roy [Department of Physics, University of the Western Cape, Cape Town 7535 (South Africa); Bacon, David J.; Nichol, Robert C.; Campbell, Heather; D'Andrea, Chris B. [Institute of Cosmology and Gravitation, University of Portsmouth, Portsmouth, PO1 3FX (United Kingdom); Clarkson, Chris [Astrophysics, Cosmology and Gravity Centre (ACGC), Department of Mathematics and Applied Mathematics, University of Cape Town, Rondebosch 7701 (South Africa); Bassett, Bruce A. [South African Astronomical Observatory, P.O. Box 9, Observatory 7935 (South Africa); Cinabro, David [Wayne State University, Department of Physics and Astronomy, Detroit, MI 48202 (United States); Finley, David A.; Frieman, Joshua A. [Center for Particle Astrophysics, Fermi National Accelerator Laboratory, P.O. Box 500, Batavia, IL 60510 (United States); Galbany, Lluis [CENTRA Centro Multidisciplinar de Astrofísica, Instituto Superior Técnico, Av. Rovisco Pais 1, 1049-001 Lisbon (Portugal); Garnavich, Peter M. [Department of Physics, University of Notre Dame, Notre Dame, IN 46556 (United States); Olmstead, Matthew D. [Department of Physics and Astronomy, University of Utah, Salt Lake City, UT 84112 (United States); Schneider, Donald P. [Department of Astronomy and Astrophysics, The Pennsylvania State University, University Park, PA 16802 (United States); Shapiro, Charles [Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, La Canada Flintridge, CA 91109 (United States); Sollerman, Jesper, E-mail: matsmith2@gmail.com [The Oskar Klein Centre, Department of Astronomy, AlbaNova, SE-106 91 Stockholm (Sweden)
2014-01-01
Using a sample of 608 Type Ia supernovae from the SDSS-II and BOSS surveys, combined with a sample of foreground galaxies from SDSS-II, we estimate the weak lensing convergence for each supernova line of sight. We find that the correlation between this measurement and the Hubble residuals is consistent with the prediction from lensing (at a significance of 1.7?). Strong correlations are also found between the residuals and supernova nuisance parameters after a linear correction is applied. When these other correlations are taken into account, the lensing signal is detected at 1.4?. We show, for the first time, that distance estimates from supernovae can be improved when lensing is incorporated, by including a new parameter in the SALT2 methodology for determining distance moduli. The recovered value of the new parameter is consistent with the lensing prediction. Using cosmic microwave background data from WMAP7, H {sub 0} data from Hubble Space Telescope and Sloan Digital Sky Survey (SDSS) Baryon acoustic oscillations measurements, we find the best-fit value of the new lensing parameter and show that the central values and uncertainties on ? {sub m} and w are unaffected. The lensing of supernovae, while only seen at marginal significance in this low-redshift sample, will be of vital importance for the next generation of surveys, such as DES and LSST, which will be systematics-dominated.
High Shear Regions in Weak Lensing Surveys Determine Cosmology
Sheng Wang; Zoltan Haiman; Morgan May; John Kehayias
2008-09-24
We propose to use a simple observable, the fractional area of "hot spots" in weak lensing mass maps which are detected with high significance, to determine background cosmological parameters. Because these high-shear regions are directly related to the physical non-linear structures of the universe, they derive cosmological information mainly from the non-linear regime of density fluctuations. We show that in combination with future cosmic microwave background (CMB) anisotropy measurements, this method can place constraints on cosmological parameters that are comparable to those from the redshift distribution of galaxy cluster abundances. In particular, adding the information from this simple shear statistic derived from an LSST-like survey to CMB anisotropy information from a Planck-like experiment improves the constraints on the dark energy parameters (energy density and equation of state) and the normalization of the matter power spectrum by over a factor of ten. The main advantage of the statistic proposed in this paper is that projection effects, normally the main source of uncertainty when determining the presence and the mass of a galaxy cluster, here serve as a source of information.
Quantum Lukewarm Black Holes and Weak Gravitational Lensing
Ghaffarnejad, H
2015-01-01
Aim of the paper is study gravitational lensing of quantum Lukewarm black hole (QLBL) and compare with results of gravitational lensing from classical Lukewarm black hole lens (CLBL). Applying numerical method, we evaluate deflection angle, image positions and magnifications in weak deflection limits. In CLBL case, bending light ray moves from both side of the lens but in QLBL case it moves from one side of the lens. Increasing amount of dimensionless cosmological parameter (quantum matter interaction parameter), rake of bending light ray is decreased in case of QLBL with respect to CLBL. Number and size of radius of Einstein rings rises in case of QLBL with respect to CLBL. Maximum number of rings is 3 in case of QLBL namely one more with respect to case of CLBL which is physically related to effects of quantum matter. There is two images (elementary and secondary) with maximum magnification which their locations are changed in case of QLBL with respect to case of CLBL. Also their locations changed by increa...
Quantum Lukewarm Black Holes and Weak Gravitational Lensing
H. Ghaffarnejad; M. A. Mojahedi
2015-07-10
Aim of the paper is study gravitational lensing of quantum Lukewarm black hole (QLBL) and compare with results of gravitational lensing from classical Lukewarm black hole lens (CLBL). Applying numerical method, we evaluate deflection angle, image positions and magnifications in weak deflection limits. In CLBL case, bending light ray moves from both side of the lens but in QLBL case it moves from one side of the lens. Increasing amount of dimensionless cosmological parameter (quantum matter interaction parameter), rake of bending light ray is decreased in case of QLBL with respect to CLBL. Number and size of radius of Einstein rings rises in case of QLBL with respect to CLBL. Maximum number of rings is 3 in case of QLBL namely one more with respect to case of CLBL which is physically related to effects of quantum matter. There is two images (elementary and secondary) with maximum magnification which their locations are changed in case of QLBL with respect to case of CLBL. Also their locations changed by increasing amount of dimensionless cosmological parameter. Same results are obtained for tangential magnification. Location of image with minimum radial magnification is lefthanded (righthanded) in case of QLBL (CLBL) and rises by decreasing the cosmological parameter. Also maximum value of the radial magnification decreases by increasing the effects of dimensionless cosmological parameter.
CP violation and Kaon weak matrix elements from Lattice QCD
Garron, Nicolas
2015-01-01
In this short review, I present the recent lattice computations of kaon weak matrix elements relevant to $K \\to \\pi\\pi$ decays and neutral kaon mixing. These matrix elements are key to the theoretical determination of the CP violation parameters $\\epsilon$ and $\\epsilon'$ . Impressive progress have been achieved recently, in particular the first realistic computation of $\\epsilon'/\\epsilon$ with physical kinematics has been reported in [1]. The novelty is the $\\Delta I = 1/2$ channel, whereas the $\\Delta I = 3/2$ contribution is now computed at several values of the lattice spacing and extrapolated to the continuum limit. I will also present the status of $B_K$ and discuss its error budget, with a particular emphasis on the perturbative error. Finally I will review the matrix elements of neutral kaon mixing beyond the standard model and will argue that the discrepancy observed by different collaborations could be explained by the renormalisation procedure of the relevant four-quark operators.
Weak power law rheology of soft glassy and gelled materials
Pedro Patricio; Catarina R. Leal
2015-09-07
We make a parallel excursion to the generalised Maxwell and Kelvin-Voigt models to find which general conditions may lead to the weak power law behaviours of the elastic and viscous moduli, $G'(w)\\sim G''(w)\\sim w^\\alpha$, with $0cells. We find that these behaviours are obtained for analogous, but essentially different power law spectra of relaxation and retardation times, stemming from the different nature of the models. The first, based on the generalised Maxwell model, retains the fluid properties of a soft glassy material (SGM) above the glass transition. The second, based on the generalised Kelvin-Voigt model, retains the elastic properties of a soft solid or gelled material. Using these models, we calculate with accuracy the power law exponents of $G'(w)\\sim w^x$ and $G''(w)\\sim w^y$, for the whole families of relaxation and retardation spectra previously obtained. Within the region corresponding to $0 y\\approx \\alpha$ and $y> x\\approx \\alpha$ for respectively the generalised Maxwell and Kelvin-Voigt models. Beyond this region, we find very different and interesting exponents.
Probing the Goldstone equivalence theorem in Heavy Weak Doublet Decays
Dutta, Bhaskar; Sanford, David; Walker, Joel W
2015-01-01
This paper investigates the decays from heavy higgsino-like weak-doublets into Z, h bosons and missing particles. When pair-produced at the LHC, the subsequent Z, h to 2l, 2b decays in the doublet decay cascade can yield 4l, 2l 2b, and 4b + MET + jets final states. Mutual observation of any two of these channels would provide information on the the associated doublets' decay branching fractions into a Z or h, thereby probing the Goldstone equivalence relation, shedding additional light on the Higgs sector of beyond the Standard Model theories, and facilitating the discrimination of various contending models, in turn. We compare the Z/h decay ratio expected in the Minimal Supersymmetric model, the Next-to Minimal Supersymmetric model and a minimal singlet-doublet dark matter model. Additionally, we conduct a full Monte Carlo analysis of the prospects for detecting the targeted final states during 14 TeV running of the LHC in the context of a representative NMSSM benchmark model.
Quark deconfinement and gluon condensate in a weak magnetic field
Alejandro Ayala; C. A. Dominguez; L. A. Hernandez; M. Loewe; Juan Cristobal Rojas; Cristian Villavicencio
2015-07-01
We study QCD finite energy sum rules (FESR) for the axial-vector current correlator in the presence of a magnetic field, in the weak field limit and at zero temperature. We find that the perturbative QCD as well as the hadronic contribution to the sum rules get explicit magnetic field-dependent corrections and that these in turn induce a magnetic field dependence on the deconfinement phenomenological parameter s_0 and on the gluon condensate. The leading corrections turn out to be quadratic in the field strength. We find from the dimension d=2 first FESR that the magnetic field dependence of s_0 is proportional to the absolute value of the light-quark condensate. Hence, it increases with increasing field strength. This implies that the parameters describing chiral symmetry restoration and deconfinement behave similarly as functions of the magnetic filed. Thus, at zero temperature the magnetic field is a catalysing agent of both chiral symmetry breaking and confinement. From the dimension d=4 second FESR we obtain the behavior of the gluon condensate in the presence of the external magnetic field. This condensate also increases with increasing field strength.
Aging generates regular motions in weakly chaotic systems
Takuma Akimoto; Eli Barkai
2012-09-27
Using intermittent maps with infinite invariant measures, we investigate the universality of time-averaged observables under aging conditions. According to Aaronson-Darling-Kac theorem, in non-aged dynamical systems with infinite invariant measures, the distribution of the normalized time averages of integrable functions converge to the Mittag-Leffler distribution. This well known theorem holds when the start of observations coincides with the start of the dynamical processes. Introducing a concept of the aging limit where the aging time $t_a$ and the total measurement time $t$ goes to infinity while the aging ratio $t_a/t$ is a constant, we obtain a novel distributional limit theorem of time-averaged observables integrable with respect to the infinite invariant density. Applying the theorem to the Lyapunov exponent in intermittent maps, we find that regular motions and a weakly chaotic behavior coexist in the aging limit. This mixed type of dynamics is controlled by the aging ratio and hence is very different from the usual scenario of regular and chaotic motions in Hamiltonian systems. The probability of finding regular motions in non-aged processes is zero, while in the aging regime it is finite and it increases when system ages.
An Extended Magnetohydrodynamics Model for Relativistic Weakly Collisional Plasmas
Chandra, Mani; Foucart, Francois; Quataert, Eliot
2015-01-01
Black holes that accrete far below the Eddington limit are believed to accrete through a geometrically thick, optically thin, rotationally supported plasma that we will refer to as a radiatively inefficient accretion flow (RIAF). RIAFs are typically collisionless in the sense that the Coulomb mean free path is large compared to $GM/c^2$, and relativistically hot near the event horizon. In this paper we develop a phenomenological model for the plasma in RIAFs, motivated by the application to sources such as Sgr A* and M87. The model is derived using Israel-Stewart theory, which considers deviations up to second order from thermal equilibrium, but modified for a magnetized plasma. This leads to thermal conduction along magnetic field lines and a difference in pressure, parallel and perpendicular to the field lines (which is equivalent to anisotrotropic viscosity). In the non-relativistic limit, our model reduces to the widely used Braginskii theory of magnetized, weakly collisional plasmas. We compare our model...
An Extended Magnetohydrodynamics Model for Relativistic Weakly Collisional Plasmas
Mani Chandra; Charles F. Gammie; Francois Foucart; Eliot Quataert
2015-08-04
Black holes that accrete far below the Eddington limit are believed to accrete through a geometrically thick, optically thin, rotationally supported plasma that we will refer to as a radiatively inefficient accretion flow (RIAF). RIAFs are typically collisionless in the sense that the Coulomb mean free path is large compared to $GM/c^2$, and relativistically hot near the event horizon. In this paper we develop a phenomenological model for the plasma in RIAFs, motivated by the application to sources such as Sgr A* and M87. The model is derived using Israel-Stewart theory, which considers deviations up to second order from thermal equilibrium, but modified for a magnetized plasma. This leads to thermal conduction along magnetic field lines and a difference in pressure, parallel and perpendicular to the field lines (which is equivalent to anisotrotropic viscosity). In the non-relativistic limit, our model reduces to the widely used Braginskii theory of magnetized, weakly collisional plasmas. We compare our model to the existing literature on dissipative relativistic fluids, describe the linear theory of the plasma, and elucidate the physical meaning of the free parameters in the model. We also describe limits of the model when the conduction is saturated and when the viscosity implies a large pressure anisotropy. In future work, the formalism developed in this paper will be used in numerical models of RIAFs to assess the importance of non-ideal processes for the dynamics and radiative properties of slowly accreting black holes.
Chemomechanical mapping of ligandreceptor binding kinetics on cells
Van Vliet, Krystyn J.
Chemomechanical mapping of ligandreceptor binding kinetics on cells Sunyoung Lee, Jelena Mandic, Providence, RI, April 23, 2007 (received for review January 2, 2007) The binding kinetics between cell activity. Modeling and prediction of receptor-mediated cell func- tions are facilitated by measurement
Water at biomolecular binding interfaces Zheng Li and Themis Lazaridis*
Lazaridis, Themis
Water at biomolecular binding interfaces Zheng Li and Themis Lazaridis* Received 29th August 2006.1039/b612449f Water molecules are often found at the binding interface of biomolecular complexes Waals interactions. Recent studies have demonstrated the importance of taking such water molecules
Hydrogen Bonding Penalty upon Ligand Binding Hongtao Zhao, Danzhi Huang*
Caflisch, Amedeo
Hydrogen Bonding Penalty upon Ligand Binding Hongtao Zhao, Danzhi Huang* Department of Biochemistry, University of Zurich, Zurich, Switzerland Abstract Ligand binding involves breakage of hydrogen bonds with water molecules and formation of new hydrogen bonds between protein and ligand. In this work, the change
ORIGINAL ARTICLE Analysis of RUNX1 binding site and RAPTOR
Abecasis, Goncalo
ORIGINAL ARTICLE Analysis of RUNX1 binding site and RAPTOR polymorphisms in psoriasis: no evidence psoriasis and single nucleotide polymorphisms (SNPs) mapping to distal chromosome 17q, including a disease for the previously identified RUNX1 binding site or for the RAPTOR locus as genetic determinants of psoriasis
Performance-Guided Character Bind Pose for Deformations
Pena, Benito
2011-08-08
Current production methods for creating a motion system for a deformable digital character model involve providing an underlying joint structure based o of a T-Pose, A-Pose or another arbitrary bind pose of the character. A bind pose is required...
NUCLEAR FISSION AND FUSION 6.A Nuclear Binding Energies
Boal, David
CHAPTER 6 NUCLEAR FISSION AND FUSION 6.A Nuclear Binding Energies A nucleus is characterized emphasis on the nuclear charge, the mass number of a nucleus plays a large role in its binding energy, and is denoted by 7Li. Some further items from the nuclear lexicon: nuclei with the same Z and differing N
Statistical weaknesses in the alleged RC4 keystream generator Marina Pudovkina
International Association for Cryptologic Research (IACR)
1 Statistical weaknesses in the alleged RC4 keystream generator Marina Pudovkina Moscow Engineering RC4 keystream generator is an algorithm for generating an arbitrarily long pseudorandom sequences
Alavi, Ali
Water on BN doped benzene: A hard test for exchange-correlation functionals and the impact of exact on benzene, coronene, and graphene from quantum Monte Carlo calculations J. Chem. Phys. 134, 134701 (2011); 10.1063/1.3569134 The water-benzene interaction: Insight from electronic structure theories J. Chem
Shubina-McGresham, Maria
2012-10-19
Characterization of allosteric properties of phosphofructokinase from the extreme thermophile Thermus thermophilus (TtPFK) using thermodynamic linkage analysis revealed several peculiarities. Inhibition and activation of ...
Nonmesonic Weak Decay Dynamics from proton spectra of $?$-Hypernuclei
Franjo Krmpotic; Cláudio De Conti
2015-03-06
A novel comparison between the data and the theory is proposed for the nonmesonic (NM) weak decay of hypernuclei. Instead of confronting the primary decay rates, as is usually done, we focus attention on the effective decay rates that are straightforwardly related with the number of emitted particles. Proton kinetic energy spectra of $^5_\\Lambda$He, $^7_\\Lambda$Li, $^9_\\Lambda$Be, $^{11}_\\Lambda$B, $^{12}_{\\Lambda}$C, $^{13}_\\Lambda$C, $^{15}_{\\Lambda}$N and $^{16}_{\\Lambda}$O, measured by FINUDA, are evaluated theoretically. The Independent Particle Shell Model (IPSM) is used as the nuclear structure framework, while the dynamics is described by the One-Meson-Exchange (OME) potential. Only for the $^{5}_{\\Lambda}$He, $^{7}_{\\Lambda}$Li, and $^{12}_{\\Lambda}$C hypernuclei is it possible to make a comparison with the data, since for the rest there is no published experimental information on number of produced hypernuclei. Considering solely the one-nucleon-induced ($1N$-NM) decay channel, the theory reproduces correctly the shapes of all three spectra at medium and high energies ($E_p \\geq 40 $ MeV). Yet, it greatly overestimates their magnitudes, as well as the corresponding transition rates when the full OME ($\\pi+K+ \\eta+\\rho+\\omega+K^*$) model is used. The agreement is much improved when only the $\\pi+K$ mesons with soft dipole cutoff parameters participate in the decay process. We find that the IPSM is a fair first order approximation to disentangle the dynamics of the $1N$-NM decay, the knowledge of which is indispensable to inquire about the baryon-baryon strangeness-flipping interaction. It is shown that the IPSM provides very useful insights regarding the determination the $2N$-NM decay rate. In a new analysis of the FINUDA data, we derive two results for this quantity with one of them close to that obtained previously.
Weakly Ionized Plasmas in Hypersonics: Fundamental Kinetics and Flight Applications
Macheret, Sergey
2005-05-16
The paper reviews some of the recent studies of applications of weakly ionized plasmas to supersonic/hypersonic flight. Plasmas can be used simply as means of delivering energy (heating) to the flow, and also for electromagnetic flow control and magnetohydrodynamic (MHD) power generation. Plasma and MHD control can be especially effective in transient off-design flight regimes. In cold air flow, nonequilibrium plasmas must be created, and the ionization power budget determines design, performance envelope, and the very practicality of plasma/MHD devices. The minimum power budget is provided by electron beams and repetitive high-voltage nanosecond pulses, and the paper describes theoretical and computational modeling of plasmas created by the beams and repetitive pulses. The models include coupled equations for non-local and unsteady electron energy distribution function (modeled in forward-back approximation), plasma kinetics, and electric field. Recent experimental studies at Princeton University have successfully demonstrated stable diffuse plasmas sustained by repetitive nanosecond pulses in supersonic air flow, and for the first time have demonstrated the existence of MHD effects in such plasmas. Cold-air hypersonic MHD devices are shown to permit optimization of scramjet inlets at Mach numbers higher than the design value, while operating in self-powered regime. Plasma energy addition upstream of the inlet throat can increase the thrust by capturing more air (Virtual Cowl), or it can reduce the flow Mach number and thus eliminate the need for an isolator duct. In the latter two cases, the power that needs to be supplied to the plasma would be generated by an MHD generator downstream of the combustor, thus forming the 'reverse energy bypass' scheme. MHD power generation on board reentry vehicles is also discussed.
Combining weak-lensing tomography and spectroscopic redshift surveys
DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)
Cai, Yan -Chuan; Bernstein, Gary
2012-05-11
Redshift space distortion (RSD) is a powerful way of measuring the growth of structure and testing General Relativity, but it is limited by cosmic variance and the degeneracy between galaxy bias b and the growth rate factor f. The cross-correlation of lensing shear with the galaxy density field can in principle measure b in a manner free from cosmic variance limits, breaking the f-b degeneracy and allowing inference of the matter power spectrum from the galaxy survey. We analyze the growth constraints from a realistic tomographic weak lensing photo-z survey combined with a spectroscopic galaxy redshift survey over the samemore »sky area. For sky coverage fsky = 0.5, analysis of the transverse modes measures b to 2-3% accuracy per ?z = 0.1 bin at z –2 are measured in the lensing survey and all halos with M > Mmin = 1013h–1M? have spectra. For the gravitational growth parameter parameter ? (f = ??m), combining the lensing information with RSD analysis of non-transverse modes yields accuracy ?(?) ? 0.01. Adding lensing information to the RSD survey improves \\sigma(\\gamma) by an amount equivalent to a 3x (10x) increase in RSD survey area when the spectroscopic survey extends down to halo mass 1013.5 (1014) h–1 M?. We also find that the ?(?) of overlapping surveys is equivalent to that of surveys 1.5-2 times larger if they are separated on the sky. This gain is greatest when the spectroscopic mass threshold is 1013 -1014 h–1 M?, similar to LRG surveys. The gain of overlapping surveys is reduced for very deep or very shallow spectroscopic surveys, but any practical surveys are more powerful when overlapped than when separated. As a result, the gain of overlapped surveys is larger in the case when the primordial power spectrum normalization is uncertain by > 0.5%.« less
Measuring primordial non-Gaussianity with weak-lensing surveys
Stefan Hilbert; Laura Marian; Robert E. Smith; Vincent Desjacques
2012-11-02
We study the ability of future weak lensing (WL) surveys to constrain primordial non-Gaussianity of the local type. We use a large ensemble of simulated WL maps with survey specifications relevant to Euclid and LSST. The simulations assume Cold Dark Matter cosmologies that vary certain parameters around fiducial values: the non-Gaussianity parameter f_NL, the matter density parameter Omega_m, the amplitude of the matter power spectrum sigma_8, the spectral index of the primordial power spectrum n_s, and the dark-energy equation-of-state parameter w_0. We assess the sensitivity of the cosmic shear correlation functions, the third-order aperture mass statistics, and the abundance of shear peaks to these parameters. We find that each of the considered probes provides unmarginalized constraints of Delta f_NL ~ 20 on f_NL. Marginalized constraints from any individual WL probe are much weaker due to strong correlations between parameters. However, the parameter errors can be substantially reduced by combining information from different WL probes. Combining all WL probes yields the following marginal (68% confidence level) uncertainties: Delta f_NL ~ 50, Delta Omega_m ~ 0.002, Delta sigma_8 ~ 0.004, Delta n_s ~ 0.007, and Delta w_0 ~ 0.03. We examine the bias induced by neglecting f_NL on the constraints on the other parameters. We find sigma_8 and w_0 to be the most affected. Moreover, neglecting non-Gaussianity leads to a severe underestimation of the uncertainties in the other cosmological parameters.
McIntosh, Lawrence P.
Calcium Binding by the N-Terminal Cellulose-Binding Domain from Cellulomonas fimi -1,4-Glucanase, 1998 ABSTRACT: The interaction of the N-terminal cellulose-binding domain, CBDN1, from Cellulomonas-state stability. Enzymes that degrade cellulose often contain one or more domains that mediate binding
COS Ciphers are not "extremely weak" ! The Design Rationale of COS Ciphers
International Association for Cryptologic Research (IACR)
COS Ciphers are not "extremely weak" ! The Design Rationale of COS Ciphers Eric Filiol ESAT summarizes the results of Babbage's cryptanalysis of COS ciphers and shows that in fact COS ciphers are not weak as claimed. COS ciphers have been designed according a novel conception of encryption directly
Bounds on the Mobility of Electrons in Weakly Ionized Plasmas A. Rokhlenko, Department energy of electrons, driven by an external field in a weakly ionized plasma (swarm approximation. The bounds prove rigorously that it is possible to increase the electron mobility by the addition of suitably
Existence of global weak solution for a reduced gravity two and a half layer model
Guo, Zhenhua Li, Zilai Yao, Lei
2013-12-15
We investigate the existence of global weak solution to a reduced gravity two and a half layer model in one-dimensional bounded spatial domain or periodic domain. Also, we show that any possible vacuum state has to vanish within finite time, then the weak solution becomes a unique strong one.
INTRODUCTION Weakly electric knifefish have been studied for several decades to
Curet, Oscar M.
the mechanical principles of force generation by the ribbon fin in the context of the South American weakly the electric field generator, and movement of the tail causes modulations of the field that are more than3490 INTRODUCTION Weakly electric knifefish have been studied for several decades to gain insights
Generation of strong mesoscale eddies by weak ocean gyres by Michael A. Spall1
Generation of strong mesoscale eddies by weak ocean gyres by Michael A. Spall1 ABSTRACT The generation of strong mesoscale variability through instability of the large-scale circulation in the interior of oceanic gyres is addressed. While previous studies have shown that eddies generated from weakly sheared
PHYSICAL REVIEW E 83, 066216 (2011) "Weak quantum chaos" and its resistor network modeling
Cohen, Doron
2011-01-01
PHYSICAL REVIEW E 83, 066216 (2011) "Weak quantum chaos" and its resistor network modeling number(s): 05.45.Mt, 03.65.-w, 73.23.-b I. INTRODUCTION So-called quantum chaos is the study of quantized. This is the case if we have weak quantum chaos (WQC) circumstances, in which the traditional RMT modeling does
Freezing and orientational order in weakly anisotropic fluids Hyung-June Woo and Xueyu Song
Song, Xueyu
Freezing and orientational order in weakly anisotropic fluids Hyung-June Woo and Xueyu Song 2001 A simple theoretical method of studying the effect of weak anisotropy on the freezing of classical to the freezing of hard dumbbell fluids yields results in good agreement with simulations. DOI: 10.1103/Phys
ON THE ENERGY SPECTRUM FOR WEAK SOLUTIONS OF THE NAVIER-STOKES EQUATIONS
Mazzucato, Anna
ON THE ENERGY SPECTRUM FOR WEAK SOLUTIONS OF THE NAVIER-STOKES EQUATIONS ANNA L. MAZZUCATO Abstract. We consider the decay at high wavenumbers of the energy spec- trum for weak solutions to the three to a class of solutions with infinite global energy by localiz- ing the Navier-Stokes equation. We consider
Complete Spectrum of Kinetic Eigenmodes for Plasma Oscillations in a Weakly Collisional Plasma
Ng, Chung-Sang
Complete Spectrum of Kinetic Eigenmodes for Plasma Oscillations in a Weakly Collisional Plasma C. S. These eigenmodes, which are smooth and compose a complete discrete spectrum, play the same role for weakly and completeness theorems [2,3]. In most situations of physical interest where the initial conditions are smooth
ON THE CONVERGENCE RATE OF OPERATOR SPLITTING FOR WEAKLY COUPLED SYSTEMS OF HAMILTON-JACOBI for weakly coupled systems of Hamilton-Jacobi equations, we establish a linear L 1 convergence rate of operator splitting for scalar Hamilton-Jacobi equations with source term. 1. Introduction The purpose
Weak charge form factor and radius of 208Pb through parity violation in electron scattering
DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)
Horowitz, C J; Jen, C -M; Rakhman, A; Souder, P A; Dalton, M M; Liyanage, N; Paschke, K D; Saenboonruang, K; Silwal, R; Franklin, G B; Friend, M; Quinn, B; Kumar, K S; McNulty, D; Mercado, L; Riordan, S; Wexler, J
2012-03-01
We use distorted wave electron scattering calculations to extract the weak charge form factor FW(q?), the weak charge radius RW, and the point neutron radius Rn, of 208Pb from the PREX parity violating asymmetry measurement. The form factor is the Fourier transform of the weak charge density at the average momentum transfer q? = 0.475 fm-1. We find FW(q?) = 0.204 ± 0.028(exp) ± 0.001(model). We use the Helm model to infer the weak radius from FW(q?). We find RW = 5.826 ± 0.181(exp) ± 0.027(model) fm. Here the exp error includes PREX statistical and systematic errors, while the model error describes the uncertainty in RW from uncertainties in the surface thickness ? of the weak charge density. The weak radius is larger than the charge radius, implying a 'weak charge skin' where the surface region is relatively enriched in weak charges compared to (electromagnetic) charges. We extract the point neutron radius Rn = 5.751 ± 0.175 (exp) ± 0.026(model) ± 0.005(strange) fm, from RW. Here there is only a very small error (strange) from possible strange quark contributions. We find Rn to be slightly smaller than RW because of the nucleon's size. Finally, we find a neutron skin thickness of Rn-Rp = 0.302 ± 0.175 (exp) ± 0.026 (model) ± 0.005 (strange) fm, where Rp is the point proton radius.
Volume 50, Number 4 2009 361 Weakly electric fishes have been an important model system
Chacron, Maurice
Volume 50, Number 4 2009 361 Abstract Weakly electric fishes have been an important model system in behavioral neuroscience for more than 40 years. These fishes use a specialized electric organ to produce fish. Weakly electric fish have been routinely used in tightly con- trolled neurophysiological
Liu, Peng; Stajich, Jason E
2015-01-01
a! chitin9binding! module. ! Appl! Microbiol! Biotechnol. !Species9specific! chitin9binding! module! 18! expansion! in!of the Carbohydrate Binding Module 18 gene family in the
Page 1 A dedicated binding mechanism for the visual control of movement
Diedrichsen, Jörn
Page 1 A dedicated binding mechanism for the visual control of movement results therefore suggest the existence of a dedicated visuo-motor binding mechanism visual target information · A dedicated visuo-motor binding mechanism links visual
Applications of Laminar Weak-Link Mechanisms for Ultraprecision Synchrotron Radiation Instruments
Shu, D.; Toellner, T. S.; Alp, E. E.; Maser, J.; Ilavsky, J.; Shastri, S. D.; Lee, P. L.; Narayanan, S.; Long, G. G. [Advanced Photon Source, Argonne National Laboratory, Argonne, IL 60439 (United States)
2007-01-19
Unlike traditional kinematic flexure mechanisms, laminar overconstrained weak-link mechanisms provide much higher structure stiffness and stability. Using a laminar structure configured and manufactured by chemical etching and lithography techniques, we are able to design and build linear and rotary weak-link mechanisms with ultrahigh positioning sensitivity and stability for synchrotron radiation applications. Applications of laminar rotary weak-link mechanism include: high-energy-resolution monochromators for inelastic x-ray scattering and x-ray analyzers for ultra-small-angle scattering and powder-diffraction experiments. Applications of laminar linear weak-link mechanism include high-stiffness piezo-driven stages with subnanometer resolution for an x-ray microscope. In this paper, we summarize the recent designs and applications of the laminar weak-link mechanisms at the Advanced Photon Source.
Shishova,E.; Yu, F.; Miller, D.; Faraldos, J.; Zhao, Y.; Coates, R.; Allemann, R.; Cane, D.; Christianson, D.
2008-01-01
The universal sesquiterpene precursor, farnesyl diphosphate (FPP), is cyclized in an Mg2+-dependent reaction catalyzed by the tetrameric aristolochene synthase from Aspergillus terreus to form the bicyclic hydrocarbon aristolochene and a pyrophosphate anion (PPi) coproduct. The 2.1- Angstroms resolution crystal structure determined from crystals soaked with FPP reveals the binding of intact FPP to monomers A-C, and the binding of PPi and Mg2+B to monomer D. The 1.89- Angstroms resolution structure of the complex with 2-fluorofarnesyl diphosphate (2F-FPP) reveals 2F-FPP binding to all subunits of the tetramer, with Mg2+Baccompanying the binding of this analogue only in monomer D. All monomers adopt open activesite conformations in these complexes, but slight structural changes in monomers C and D of each complex reflect the very initial stages of a conformational transition to the closed state. Finally, the 2.4- Angstroms resolution structure of the complex with 12,13-difluorofarnesyl diphosphate (DF-FPP) reveals the binding of intact DF-FPP to monomers A-C in the open conformation and the binding of PPi, Mg2+B, and Mg2+C to monomer D in a predominantly closed conformation. Taken together, these structures provide 12 independent 'snapshots' of substrate or product complexes that suggest a possible sequence for metal ion binding and conformational changes required for catalysis.
Hussey, Richard S.
Cellulose Binding Protein from the Parasitic Nematode Heterodera schachtii Interacts Heterodera glycines also produces a cellulose binding protein (Hg CBP) secretory protein. To determine
Post-transcriptional coordination by an RNA-binding protein
Wolf, Joshua Jaeger
2010-01-01
RNA-binding proteins can regulate the stability, localization, and translation of their target mRNAs. Post-transcriptional regulation can orchestrate dynamic changes in gene expression, and can coordinate multiple cellular ...
Original article Distribution of endogenous retinoids, retinoid binding
Paris-Sud XI, Université de
of specific retinoid-binding proteins was investigated; these are involved in vitamin A transport, metabolism is induced by a concentration gradient (high posteri- orly) of all-trans-RA along the anterior-p
Metal binding proteins, recombinant host cells and methods
Summers, Anne O.; Caguiat, Jonathan J.
2004-06-15
The present disclosure provides artificial heavy metal binding proteins termed chelons by the inventors. These chelons bind cadmium and/or mercuric ions with relatively high affinity. Also disclosed are coding sequences, recombinant DNA molecules and recombinant host cells comprising those recombinant DNA molecules for expression of the chelon proteins. In the recombinant host cells or transgenic plants, the chelons can be used to bind heavy metals taken up from contaminated soil, groundwater or irrigation water and to concentrate and sequester those ions. Recombinant enteric bacteria can be used within the gastrointestinal tracts of animals or humans exposed to toxic metal ions such as mercury and/or cadmium, where the chelon recombinantly expressed in chosen in accordance with the ion to be rededicated. Alternatively, the chelons can be immobilized to solid supports to bind and concentrate heavy metals from a contaminated aqueous medium including biological fluids.
Linear Scaling of the Exciton Binding Energy versus the Band...
Office of Scientific and Technical Information (OSTI)
Linear Scaling of the Exciton Binding Energy versus the Band Gap of Two-Dimensional Materials This content will become publicly available on August 6, 2016 Prev Next Title:...
Second-order susceptibility from a tight-binding Hamiltonian
Dumitrica, T.; Graves, JS; Allen, Roland E.
1998-01-01
Using a new formalism that modifies a tight-binding Hamiltonian to include interaction with a time-dependent electromagnetic field, we have obtained an analytical expression for the second-order susceptibility. This expression has been used...
Sampling Weak Values: A Non-Linear Bayesian Model for Non-Ideal Quantum Measurements
Alonso Botero
2003-06-11
A model is proposed for the statistical analysis of arbitrary-strength quantum measurements, based on a picture of "sampling weak values" from different configurations of the system. The model is comprised of two elements: a "local weak value" and a "likelihood factor". The first describes the response of an idealized weak measurement situation where the back-reaction on the system is perfectly controlled. The second assigns a weight factor to possible configurations of the system. The distribution of the data in a measurement of arbitrary strength may the be viewed as the net result of interfering different samples weighted by the likelihood factor, each of which implements a weak measurement of a different local weak value. It is shown that the mean and variance of the data can be connected directly to the means and variances of the sampled weak values. The model is then applied to a situation similar to a phase transition, where the distribution of the data exhibits two qualitatively different shapes as the strength parameter is slightly varied away from a critical value: one below the critical point, where an unusual weak value is resolved, the other above the critical point, where the spectrum of the measured observable is resolved. In the picture of sampling, the transition corresponds to a qualitative change in the sampling profile brought about by the competition between the prior sampling distribution and the likelihood factor.
MCM ring hexamerization is a prerequisite for DNA-binding
DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)
Froelich, Clifford A.; Nourse, Amanda; Enemark, Eric J.
2015-09-13
The hexameric Minichromosome Maintenance (MCM) protein complex forms a ring that unwinds DNA at the replication fork in eukaryotes and archaea. Our recent crystal structure of an archaeal MCM N-terminal domain bound to single-stranded DNA (ssDNA) revealed ssDNA associating across tight subunit interfaces but not at the loose interfaces, indicating that DNA-binding is governed not only by the DNA-binding residues of the subunits (MCM ssDNA-binding motif, MSSB) but also by the relative orientation of the subunits. We now extend these findings to show that DNA-binding by the MCM N-terminal domain of the archaeal organism Pyrococcus furiosus occurs specifically in themore »hexameric oligomeric form. We show that mutants defective for hexamerization are defective in binding ssDNA despite retaining all the residues observed to interact with ssDNA in the crystal structure. One mutation that exhibits severely defective hexamerization and ssDNA-binding is at a conserved phenylalanine that aligns with the mouse Mcm4(Chaos3) mutation associated with chromosomal instability, cancer, and decreased intersubunit association.« less
Method and apparatus for evaluating structural weakness in polymer matrix composites
Wachter, Eric A. (Oak Ridge, TN); Fisher, Walter G. (Knoxville, TN)
1996-01-01
A method and apparatus for evaluating structural weaknesses in polymer matrix composites is described. An object to be studied is illuminated with laser radiation and fluorescence emanating therefrom is collected and filtered. The fluorescence is then imaged and the image is studied to determine fluorescence intensity over the surface of the object being studied and the wavelength of maximum fluorescent intensity. Such images provide a map of the structural integrity of the part being studied and weaknesses, particularly weaknesses created by exposure of the object to heat, are readily visible in the image.
Method and apparatus for evaluating structural weakness in polymer matrix composites
Wachter, E.A.; Fisher, W.G.
1996-01-09
A method and apparatus for evaluating structural weaknesses in polymer matrix composites is described. An object to be studied is illuminated with laser radiation and fluorescence emanating therefrom is collected and filtered. The fluorescence is then imaged and the image is studied to determine fluorescence intensity over the surface of the object being studied and the wavelength of maximum fluorescent intensity. Such images provide a map of the structural integrity of the part being studied and weaknesses, particularly weaknesses created by exposure of the object to heat, are readily visible in the image. 6 figs.
Samutpraphoot, Polnop
We present a simple method for narrowing the intrinsic Lorentzian linewidth of a commercial ultraviolet grating extended-cavity diode laser (TOPTICA DL Pro) using weak optical feedback from a long external cavity. We achieve ...
A weak-value interpretation of the Schwinger mechanism of massless/massive pair productions
Kazuhiro Yokota; Nobuyuki Imoto
2015-04-28
According to the Schwinger mechanism, a uniform electric field brings about pair productions in vacuum; the relationship between the production rate and the electric field is different, depending on the dimension of the system. In this paper, we make an offer of another model for the pair productions, in which weak values are incorporated: energy fluctuations trigger the pair production, and a weak value appears as the velocity of a particle there. Although our model is only available for the approximation of the pair production rates, the weak value reveals a new aspect of the pair production. Especially, within the first order, our estimation approximately agrees with the exponential decreasing rate of the Landau-Zener tunneling through the mass energy gap. In other words, such tunneling can be associated with energy fluctuations via the weak value, when the tunneling gap can be regarded as so small due to the high electric field.
ABOUT TRANSFINITE COMPOSITIONS OF WEAK EQUIVALENCES OF HIGHER DIMENSIONAL TRANSITION SYSTEMS
Gaucher, Philippe - Laboratoire Preuves, Programmes et Systèmes, Université Paris 7
transition systems WTS and CTS. All generating cofibrations of WTS, CTS, CTS+ are maps between weak transition systems containing a finite number of states and actions by [Gau11, Proposition 5.4] for WTS
Haun, Phil M
2010-01-01
Great Powers often adopt coercive strategies, threatening or using limited force to convince weak states to comply with their demands. While coercive strategies have succeeded in just over half of asymmetric crises since ...
Search for Low-Mass Weakly Interacting Massive Particles with SuperCDMS
Agnese, R.
We report a first search for weakly interacting massive particles (WIMPs) using the background rejection capabilities of SuperCDMS. An exposure of 577 kg days was analyzed for WIMPs with mass < 30??GeV/c[superscript 2], ...
Efficient weakly-radiative wireless energy transfer: An EIT-like approach
Hamam, Rafif E.
Inspired by a quantum interference phenomenon known in the atomic physics community as electromagnetically induced transparency (EIT), we propose an efficient weakly radiative wireless energy transfer scheme between two ...
Hwang, D S; Ne'eman, Yuval
1994-01-01
BRST quantization of SU(2/1) electro-weak theory in the superconnection approach - and the Higgs meson mass
Weak lensing of large scale structure in the presence of screening
Tessore, Nicolas; Metcalf, R Benton; Ferreira, Pedro G
2015-01-01
A number of alternatives to general relativity exhibit gravitational screening in the non-linear regime of structure formation. We describe a set of algorithms that can produce weak lensing maps of large scale structure in such theories and can be used to generate mock surveys for cosmological analysis. By analysing a few basic statistics we indicate how these alternatives can be distinguished from general relativity with future weak lensing surveys.
Analytic Expression of the Genus in Weakly Non-Gaussian Field Induced by Gravity
T. Matsubara
1994-05-16
The gravitational evolution of the genus of the density field in large-scale structure is analytically studied in a weakly nonlinear regime using second-order perturbation theory. Weakly nonlinear evolution produces asymmetry in the symmetric genus curve for Gaussian initial density field. The effect of smoothing the density field in perturbation theory on the genus curve is also evaluated and gives the dependence of the asymmetry of the genus curve on spectra of initial fluctuations.
Harrison, Ian
2015-01-01
This document was submitted as supporting material to an Engineering Change Proposal (ECP) for the Square Kilometre Array (SKA). This ECP requests gridded visibilities as an extra imaging data product from the SKA, in order to enable bespoke analysis techniques to measure source morphologies to the accuracy necessary for precision cosmology with radio weak lensing. We also discuss the properties of an SKA weak lensing data set and potential overlaps with other cosmology science goals.
A compilation of weak gravitational lensing studies of clusters of galaxies
H. Dahle
2007-01-21
We present a list of clusters that have had their dark matter content measured using weak gravitational lensing. The list consists of 139 clusters, with weak lensing measurements reported in 64 different publications. Details are provided about the selection criteria and some basic properties of the sample, such as the redshift distribution. An electronic, sortable version of this list with links to public database information on the clusters and publications is provided at http://folk.uio.no/hdahle/WLclusters.html
Weak charge form factor and radius of 208Pb through parity violation in electron scattering
DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)
Horowitz, C. J.; Ahmed, Z.; Jen, C. -M.; Rakhman, A.; Souder, P. A.; Dalton, M. M.; Liyanage, N.; Paschke, K. D.; Saenboonruang, K.; Silwal, R.; et al
2012-03-26
We use distorted wave electron scattering calculations to extract the weak charge form factor FW($\\bar{q}$), the weak charge radius RW, and the point neutron radius Rn, of 208Pb from the PREX parity violating asymmetry measurement. The form factor is the Fourier transform of the weak charge density at the average momentum transfer $\\bar{q}$ = 0.475 fm-1. We find FW($\\bar{q}$) = 0.204 ± 0.028(exp) ± 0.001(model). We use the Helm model to infer the weak radius from FW($\\bar{q}$). We find RW = 5.826 ± 0.181(exp) ± 0.027(model) fm. Here the exp error includes PREX statistical and systematic errors, while the modelmore »error describes the uncertainty in RW from uncertainties in the surface thickness ? of the weak charge density. The weak radius is larger than the charge radius, implying a 'weak charge skin' where the surface region is relatively enriched in weak charges compared to (electromagnetic) charges. We extract the point neutron radius Rn = 5.751 ± 0.175 (exp) ± 0.026(model) ± 0.005(strange) fm, from RW. Here there is only a very small error (strange) from possible strange quark contributions. We find Rn to be slightly smaller than RW because of the nucleon's size. As a result, we find a neutron skin thickness of Rn-Rp = 0.302 ± 0.175 (exp) ± 0.026 (model) ± 0.005 (strange) fm, where Rp is the point proton radius.« less
Weak Restricted and Very Restricted Operators on L2 J. Marshall Ash
Ash, J. Marshall
Weak Restricted and Very Restricted Operators on L2 J. Marshall Ash Transactions of the American OPERATORS ON L* BY J. MARSHALL ASH' Dedicated to the memory of Kurel de Leeuw ABSTRACT.A battlement per page #12;676 J. M. ASH Say that T is of weak type (2,2) and write T E w.(2,2) if (1.4) holds
Acid Gas Capture Using CO2-Binding Organic Liquids
Heldebrant, David J.; Koech, Phillip K.; Rainbolt, James E.; Zheng, Feng
2010-11-10
Current chemical CO2 scrubbing technology is primarily aqueous alkanolamine based. These systems rapidly bind CO2 (forming water-soluble carbamate and bicarbonate salts) however, the process has serious disadvantages. The concentration of monoethanolamine rarely exceeds 30 wt % due to the corrosive nature of the solution, and this reduces the maximum CO2 volumetric (?108 g/L) and gravimetric capacity (?7 wt%) of the CO2 scrubber. The ?30 wt % loading of ethanolamine also means that a large excess of water must be pumped and heated during CO2 capture and release, and this greatly increases the energy requirements especially considering the high specific heat of water (4 j/g-1K-1). Our approach is to switch to organic systems that chemically bind CO2 as liquid alkylcarbonate salts. Our CO2-binding organic liquids have higher CO2 solubility, lower specific heats, potential for less corrosion and lower binding energies for CO2 than aqueous systems. CO2BOLs also reversibly bind and release mixed sulfur oxides. Furthermore the CO2BOL system can be direct solvent replacements for any solvent based CO2 capture systems because they are commercially available reagents and because they are fluids they would not require extensive process re-engineering.
Dynamic Structural Rearrangements Between DNA Binding Modes of E. coli SSB Protein
Lohman, Timothy M.
an oligonucleotide/oligosaccharide bind- ing (OB) fold,5,79 hence the tetramer has four po- tential ssDNA binding sites. The SSB tetramer can bind long ssDNA in a variety of binding modes depending on solutionCl) and high protein to DNA ratios, an SSB tetramer binds to ssDNA with high inter-tetramer cooperativity using
McIntosh, Lawrence P.
The Cellulose-binding Domains from Cellulomonas fimi bbb-1,4-Glucanase CenC Bind Nitroxide Spin6T 1Z3, Canada The N-terminal cellulose-binding domains CBDN1 and CBDN2 from Cellulomonas ®mi cellulase CenC each adopt a jelly-roll b-sandwich struc- ture with a cleft into which amorphous cellulose
COMPARING DENSE GALAXY CLUSTER REDSHIFT SURVEYS WITH WEAK-LENSING MAPS
Hwang, Ho Seong; Geller, Margaret J.; Zahid, H. Jabran [Smithsonian Astrophysical Observatory, 60 Garden Street, Cambridge, MA 02138 (United States); Diaferio, Antonaldo [Dipartimento di Fisica, Università degli Studi di Torino, V. Pietro Giuria 1, I-10125 Torino (Italy); Rines, Kenneth J., E-mail: hhwang@cfa.harvard.edu, E-mail: mgeller@cfa.harvard.edu, E-mail: harus.zahid@cfa.harvard.edu, E-mail: diaferio@ph.unito.it, E-mail: kenneth.rines@wwu.edu [Department of Physics and Astronomy, Western Washington University, Bellingham, WA 98225 (United States)
2014-12-20
We use dense redshift surveys of nine galaxy clusters at z ? 0.2 to compare the galaxy distribution in each system with the projected matter distribution from weak lensing. By combining 2087 new MMT/Hectospec redshifts and the data in the literature, we construct spectroscopic samples within the region of weak-lensing maps of high (70%-89%) and uniform completeness. With these dense redshift surveys, we construct galaxy number density maps using several galaxy subsamples. The shape of the main cluster concentration in the weak-lensing maps is similar to the global morphology of the number density maps based on cluster members alone, mainly dominated by red members. We cross-correlate the galaxy number density maps with the weak-lensing maps. The cross-correlation signal when we include foreground and background galaxies at 0.5z {sub cl} < z < 2z {sub cl} is 10%-23% larger than for cluster members alone at the cluster virial radius. The excess can be as high as 30% depending on the cluster. Cross-correlating the galaxy number density and weak-lensing maps suggests that superimposed structures close to the cluster in redshift space contribute more significantly to the excess cross-correlation signal than unrelated large-scale structure along the line of sight. Interestingly, the weak-lensing mass profiles are not well constrained for the clusters with the largest cross-correlation signal excesses (>20% for A383, A689, and A750). The fractional excess in the cross-correlation signal including foreground and background structures could be a useful proxy for assessing the reliability of weak-lensing cluster mass estimates.
Orientation-dependent binding energy of graphene on palladium
Kappes, Branden B.; Ebnonnasir, Abbas; Ciobanu, Cristian V. [Department of Mechanical Engineering and Materials Science Program, Colorado School of Mines, Golden, Colorado 80401 (United States)] [Department of Mechanical Engineering and Materials Science Program, Colorado School of Mines, Golden, Colorado 80401 (United States); Kodambaka, Suneel [Department of Materials Science and Engineering, University of California, Los Angeles, Los Angeles, California 90095 (United States)] [Department of Materials Science and Engineering, University of California, Los Angeles, Los Angeles, California 90095 (United States)
2013-02-04
Using density functional theory calculations, we show that the binding strength of a graphene monolayer on Pd(111) can vary between physisorption and chemisorption depending on its orientation. By studying the interfacial charge transfer, we have identified a specific four-atom carbon cluster that is responsible for the local bonding of graphene to Pd(111). The areal density of such clusters varies with the in-plane orientation of graphene, causing the binding energy to change accordingly. Similar investigations can also apply to other metal substrates and suggests that physical, chemical, and mechanical properties of graphene may be controlled by changing its orientation.
Potential sources of contamination to weak lensing measurements: constraints from N-body simulations
Catherine Heymans; Martin White; Alan Heavens; Chris Vale; Ludovic Van Waerbeke
2006-06-16
We investigate the expected correlation between the weak gravitational shear of distant galaxies and the orientation of foreground galaxies, through the use of numerical simulations. This shear-ellipticity correlation can mimic a cosmological weak lensing signal, and is potentially the limiting physical systematic effect for cosmology with future high-precision weak lensing surveys. We find that, if uncorrected, the shear-ellipticity correlation could contribute up to 10% of the weak lensing signal on scales up to 20 arcminutes, for lensing surveys with a median depth z=1. The most massive foreground galaxies are expected to cause the largest correlations, a result also seen in the Sloan Digital Sky Survey. We find that the redshift dependence of the effect is proportional to the lensing efficiency of the foreground, and this offers prospects for removal to high precision, although with some model dependence. The contamination is characterised by a weakly negative B-mode, which can be used as a diagnostic of systematic errors. We also provide more accurate predictions for a second potential source of error, the intrinsic alignment of nearby galaxies. This source of contamination is less important, however, as it can be easily removed with distance information.
Molecular Cell High-Affinity Binding of Chp1 Chromodomain
Halazonetis, Thanos
Molecular Cell Article High-Affinity Binding of Chp1 Chromodomain to K9 Methylated Histone H3, Chp1, and siRNAs derived from centro- meric repeats. Recruitment of RITS to centromeres has been establishment. Our crystal structure of Chp1's chromodomain in complex with a trimethylated lysine 9 H3 peptide
Telomeres and telomere binding proteins in Arabidopsis thaliana
Shakirov, Yevgeniy Vitalievich
2004-09-30
. Additionally, two Arabidopsis genes, AtPot1 and AtPot2, were identified and characterized. The genes encode two single-strand telomeric DNA binding proteins. AtPot1 and AtPot2 proteins can homo- and heterodimerize in vitro. Pot1 protein predominantly localizes...
CAR2 Displays Unique Ligand Binding and RXR Heterodimerization Characteristics
Omiecinski, Curtis
CAR2 Displays Unique Ligand Binding and RXR Heterodimerization Characteristics Scott S. Auerbach ABSTRACT: The constitutive androstane receptor (CAR; NR1I3) regulates the expression of genes involved in xenobiotic metabolism. Alternative splicing of the human CAR gene yields an array of mRNAs that encode
Binding of Harvested Bacterial Exopolymers to the Surface of
of the EPS showed that binding strength to calcite depended on the chemical nature of the polymer. Introduction Dissolution of calcium carbonate (calcite) affects global carbon cycling (1), the chemistry of calcium carbonate in the form of limestone or marble. Retardation of deterioration is important
A probabilistic approach to microRNA-target binding
Ogul, Hasan; Umu, Sinan U.; Bioinformatics Program, Informatics Institute, Middle East Technical University, Cankaya TR-06800, Ankara ; Tuncel, Y. Yener; Akkaya, Mahinur S.
2011-09-16
Highlights: {yields} A new probabilistic model is introduced for microRNA-target binding. {yields} The new model significantly outperforms RNAHybrid and miRTif. {yields} The experiments can unveil the effects of the type and directions of distinct base pairings. -- Abstract: Elucidation of microRNA activity is a crucial step in understanding gene regulation. One key problem in this effort is how to model the pairwise interactions of microRNAs with their targets. As this interaction is strongly mediated by their sequences, it is desired to set-up a probabilistic model to explain the binding preferences between a microRNA sequence and the sequence of a putative target. To this end, we introduce a new model of microRNA-target binding, which transforms an aligned duplex to a new sequence and defines the likelihood of this sequence using a Variable Length Markov Chain. It offers a complementary representation of microRNA-mRNA pairs for microRNA target prediction tools or other probabilistic frameworks of integrative gene regulation analysis. The performance of present model is evaluated by its ability to predict microRNA-target mRNA interaction given a mature microRNA sequence and a putative mRNA binding site. In regard to classification accuracy, it outperforms two recent methods based on thermodynamic stability and sequence complementarity. The experiments can also unveil the effects of base pairing types and non-seed region in duplex formation.
Expression and subcellular localisation of poly(A)-binding proteins
Burgess, Hannah
2010-11-24
Poly(A)-binding proteins (PABPs) are important regulators of mRNA translation and stability. In mammals four cytoplasmic PABPs with a similar domain structure have been described - PABP1, tPABP, PABP4 and ePABP. The ...
Compilation as Metacomputation: Binding Time Separation in Modular Compilers
Kamin, Sam
Compilation as Metacomputation: Binding Time Separation in Modular Compilers (Extended Abstract ings. Metacomputationstyle specification lends itself to semanticsdirected compilation, which we demonstrate by creating a modular compiler for a higherorder, imperative, Algollike language. Keywords
Methods of use of cellulose binding domain proteins
Shoseyov, O.; Shpiegl, I.; Goldstein, M.A.; Doi, R.H.
1997-09-23
A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques. 16 figs.
Workshop on gate valve pressure locking and thermal binding
Brown, E.J.
1995-07-01
The purpose of the Workshop on Gate Valve Pressure Locking and Thermal Binding was to discuss pressure locking and thermal binding issues that could lead to inoperable gate valves in both boiling water and pressurized water reactors. The goal was to foster exchange of information to develop the technical bases to understand the phenomena, identify the components that are susceptible, discuss actual events, discuss the safety significance, and illustrate known corrective actions that can prevent or limit the occurrence of pressure locking or thermal binding. The presentations were structured to cover U.S. Nuclear Regulatory Commission staff evaluation of operating experience and planned regulatory activity; industry discussions of specific events, including foreign experience, and efforts to determine causes and alleviate the affects; and valve vendor experience and recommended corrective action. The discussions indicated that identifying valves susceptible to pressure locking and thermal binding was a complex process involving knowledge of components, systems, and plant operations. The corrective action options are varied and straightforward.
Host Cell Responses Induced by Hepatitis C Virus Binding
Timmer, Jens
Host Cell Responses Induced by Hepatitis C Virus Binding Xinhua Fang,1 Mirjam B. Zeisel,1 Jochen. Blum,1 and Thomas F. Baumert1,5 Initiation of hepatitis C virus (HCV) infection is mediated by docking nitiation of hepatitis C virus (HCV) infection is me- diated by docking of the viral envelope to the hepa
Inhibition Of Call-Cell Binding By Kipid Assemblies
Nagy, Jon O. (Rodeo, CA), Bargatze, Robert F. (Bozeman, MT)
2003-12-16
This invention relates generally to the field of therapeutic compounds designed to interfere between the binding of ligands and their receptors on cell surface. More specifically, it provides products and methods for inhibiting cell migration and activation using lipid assemblies with surface recognition elements that are specific for the receptors involved in cell migration and activation.
Inhibition of cell-cell binding by lipid assemblies
Nagy, Jon O. (Rodeo, CA); Bargatze, Robert F. (Bozeman, MT)
2001-05-22
This invention relates generally to the field of therapeutic compounds designed to interfere between the binding of ligands and their receptors on cell surface. More specifically, it provides products and methods for inhibiting cell migration and activation using lipid assemblies with surface recognition elements that are specific for the receptors involved in cell migration and activation.
Automatic Generation of Tcl Bindings for C and C++ Libraries
Heidrich, Wolfgang
functions. This facility has been used to create a variety of language bindings for C libraries, ranging++ library functions to Tcl, is that they do not normally receive their arguments using this argc public member function, but since C(++) data can not be addressed directly from Tcl, string handles need
Analysis of the Vertebrate Insulator Protein CTCF-Binding
D. Green,4 Michael Q. Zhang,3 Victor V. Lobanenkov,2 and Bing Ren1, * 1 Ludwig Institute for Cancer by preventing the spread of heterochromatin and restricting transcriptional enhancers from acti- vation ex- pressed nuclear protein with 11-zinc finger (ZF) DNA- binding domain (Filippova et al., 1996
The peanut lectin-binding glycoproteins of human epidermal keratinocytes
Morrison, A.I. (Max-Planck-Institute fuer Systemphysiologie, Dortmund (West Germany)); Keeble, S.; Watt, F.M. (Imperial Cancer Research Fund, London (England))
1988-08-01
The peanut lectin (PNA) is known to bind more strongly to keratinocytes that are undergoing terminal differentiation than to proliferating keratinocytes. In order to investigate the significance of this change in cell-surface carbohydrate authors have identified the PNA-binding glycoproteins of cultured human keratinocytes and antibodies against them. Two heavily glycosylated bands of 110 and 250 kDa were resolved by PAGE of ({sup 14}C)galactose- or ({sup 14}C)mannose- and ({sup 14}C)glucosamine-labeled cell extracts eluted with galactose from PNA affinity columns. The higher molecular weight band was also detected on PNA blots of unlabeled cell extracts transferred to nitrocellulose. Both bands were sensitive to pronase digestion, but only the 250-kDa band was digested with trypsin. A rabbit antiserum that we prepared (anti-PNA-gp) immunoprecipitated both bands from cell extracts. In contrast to PNA, anti-PNA-gp bound equally to proliferating and terminally differentiating cells, indicating that some epitope(s) of the PNA-binding glycoproteins is present on the cell surface prior to terminal differentiation. When keratinocytes grown as a monolayer in low-calcium medium were switched to medium containing 2 mM calcium ions in order to induce desmosome formation and stratification, there was a dramatic redistribution of the PNA-binding glycoproteins, which became concentrated at the boundaries between cells. This may suggest a role for the glycoproteins in cell-cell interactions during stratification.
Methods of detection using a cellulose binding domain fusion product
Shoseyov, Oded (Shimshon, IL); Shpiegl, Itai (North Gallilea, IL); Goldstein, Marc A. (Davis, CA); Doi, Roy H. (Davis, CA)
1999-01-01
A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production thereof. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques.
Methods of use of cellulose binding domain proteins
Shoseyov, Oded (Karmey Yosef, IL); Shpiegl, Itai (Rehovot, IL); Goldstein, Marc A. (Davis, CA); Doi, Roy H. (Davis, CA)
1997-01-01
A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production thereof. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques.
Methods of detection using a cellulose binding domain fusion product
Shoseyov, O.; Shpiegl, I.; Goldstein, M.A.; Doi, R.H.
1999-01-05
A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques. 34 figs.
Zhao, Xiaopeng Song, Kun
2014-10-15
Metamaterials are artificial media designed to control electromagnetic wave propagation. Due to resonance, most present-day metamaterials inevitably suffer from narrow bandwidth, extremely limiting their practical applications. On the basis of tailored properties, a metamaterial within which each distinct unit cell resonates at its inherent frequency and has almost no coupling effect with the other ones, termed as weak interaction system, can be formulated. The total response of a weak interaction system can be treated as an overlap of the single resonance spectrum of each type of different unit cells. This intriguing feature therefore makes it possible to accomplish multiband or broadband metamaterials in a simple way. By introducing defects into metamaterials to form a weak interaction system, multiband and broadband electromagnetic metamaterials have first been experimentally demonstrated by our group. The similar concept can also be readily extended to acoustic and seismic metamaterials.
Chaotic Weak Chimeras and their Persistence in Coupled Populations of Phase Oscillators
Christian Bick; Peter Ashwin
2015-09-29
Nontrivial collective behavior may emerge from the interactive dynamics of many oscillatory units. Chimera states are chaotic patterns of spatially localized coherent and incoherent oscillations. The recently-introduced notion of a weak chimera gives a rigorously testable characterization of chimera states for finite-dimensional phase oscillator networks. In this paper we give some persistence results for dynamically invariant sets under perturbations and apply them to coupled populations of phase oscillators with generalized coupling. In contrast to the weak chimeras with nonpositive maximal Lyapunov exponents constructed so far, we show that weak chimeras that are chaotic can exist in the limit of vanishing coupling between coupled populations of phase oscillators. We present numerical evidence that positive Lyapunov exponents can persist for a positive measure set of this inter-population coupling strength.
Measurement of the Effective Weak Mixing Angle inpp¯?Z/?*?e+e-Events
DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)
Abazov, V.? M.; Abbott, B.; Acharya, B.? S.; Adams, M.; Adams, T.; Agnew, J.? P.; Alexeev, G.? D.; Alkhazov, G.; Alton, A.; Askew, A.; et al
2015-07-22
We present a measurement of the fundamental parameter of the standard model, the weak mixing angle sin2??eff which determines the relative strength of weak and electromagnetic interactions, in pp¯?Z/?*?e+e- events at a center of mass energy of 1.96 TeV, using data corresponding to 9.7 fb-1 of integrated luminosity collected by the D0 detector at the Fermilab Tevatron. The effective weak mixing angle is extracted from the forward-backward charge asymmetry as a function of the invariant mass around the Z boson pole. The measured value of sin2??eff=0.23147±0.00047 is the most precise measurement from light quark interactions to date, with a precisionmore »close to the best LEP and SLD results.« less
ATMOSPHERIC COMPOSITION OF WEAK G BAND STARS: CNO AND Li ABUNDANCES
Adamczak, Jens; Lambert, David L., E-mail: adamczak@astro.as.utexas.edu [McDonald Observatory, University of Texas, Austin, TX 78712 (United States)
2013-03-10
We determined the chemical composition of a large sample of weak G band stars-a rare class of G and K giants of intermediate mass with unusual abundances of C, N, and Li. We have observed 24 weak G band stars with the 2.7 m Harlan J. Smith Telescope at the McDonald Observatory and derived spectroscopic abundances for C, N, O, and Li, as well as for selected elements from Na-Eu. The results show that the atmospheres of weak G band stars are highly contaminated with CN-cycle products. The C underabundance is about a factor of 20 larger than for normal giants and the {sup 12}C/{sup 13}C ratio approaches the CN-cycle equilibrium value. In addition to the striking CN-cycle signature the strong N overabundance may indicate the presence of partially ON-cycled material in the atmospheres of the weak G band stars. The exact mechanism responsible for the transport of the elements to the surface has yet to be identified but could be induced by rapid rotation of the main sequence progenitors of the stars. The unusually high Li abundances in some of the stars are an indicator for Li production by the Cameron-Fowler mechanism. A quantitative prediction of a weak G band star's Li abundance is complicated by the strong temperature sensitivity of the mechanism and its participants. In addition to the unusual abundances of CN-cycle elements and Li, we find an overabundance of Na that is in accordance with the NeNa chain running in parallel with the CN cycle. Apart from these peculiarities, the element abundances in a weak G band star's atmosphere are consistent with those of normal giants.
Note: On-line weak signal detection via adaptive stochastic resonance
Lu, Siliang; He, Qingbo Kong, Fanrang
2014-06-15
We design an instrument with a novel embedded adaptive stochastic resonance (SR) algorithm that consists of a SR module and a digital zero crossing detection module for on-line weak signal detection in digital signal processing applications. The two modules are responsible for noise filtering and adaptive parameter configuration, respectively. The on-line weak signal detection can be stably achieved in seconds. The prototype instrument exhibits an advance of 20 dB averaged signal-to-noise ratio and 5 times averaged adjust R-square as compared to the input noisy signal, in considering different driving frequencies and noise levels.
Weakly first-order phase transitions: the epsilon expansion vs. numerical simulations
Peter Arnold; Stephen R. Sharpe; Laurence G. Yaffe; Yan Zhang
1996-10-31
Some phase transitions of cosmological interest may be weakly first-order and cannot be analyzed by a simple perturbative expansion around mean field theory. We propose a simple two-scalar model--the cubic anisotropy model--as a foil for theoretical techniques to study such transitions, and we review its similarities and dissimilarities to the electroweak phase transition in the early universe. We present numerical Monte Carlo results for various discontinuities across very weakly first-order transitions in this model and, as an example, compare them to epsilon-expansion results. For this purpose, we have computed through next-to-next-to-leading order in epsilon.
Glucose oxidation in heart-type fatty acid binding protein null mice
Adhikari, Sean
2006-10-30
Heart-type fatty acid binding protein (H-FABP) is a major fatty acid binding factor in skeletal muscles. Genetic lack of H-FABP severely impairs the esterification and oxidation of exogenous fatty acids in soleus muscles ...
Insight into Ligand Diversity and Novel Biological Roles for Family 32 Carbohydrate-Binding Modules
Eirin Lopez, Jose Maria
a new platform for the prediction of CBM binding specificity and highlight significant new targets et al. 2007). For example, Yersinia enterocolitica contains a family 32 car- bohydrate-binding module
Expression and characterisation of a novel poly(A)-binding protein, PABP5
Anderson, Ross Calley
2010-11-24
The poly(A)-binding proteins (PABPs) are a family of eukaryotic RNA-binding proteins with key roles in mRNA translation and stability. The molecular function of PABPs have been largely revealed through study of the ...
Common binding by redundant group B Sox proteins is evolutionarily conserved in Drosophila.
Carl, Sarah H.; Russell, Steven
2015-04-13
Three-way comparison of Dichaete binding. (A) Pie chart showin present in one species (47%), two species (23%) or all three species (30%). in D. melanogaster, D. simulans and D. yakuba clustered by binding affinity key and histogram shows...
Syntax-driven bindings of Spanish clitic pronoun Ivan V. Meza Ruiz
Pineda, Luis
´on con la teor´ia de binding. Los pronombres cl´iticos del espa~nol presentan un comportamiento dual dado control de objeto. Palabras clave: Pronombres cl´iticos, Teor´ia de Binding, Reflexividad, HPSG Abstract
Weak law of large numbers for some Markov chains along non homogeneous genealogies
Paris-Sud XI, Université de
Weak law of large numbers for some Markov chains along non homogeneous genealogies Vincent Bansaye goes to infinity. It is described by a discrete genealogy which may be time non-homogeneous and we pay of the trait of each individual along this genealogy and may also be time non- homogeneous. Such models
MAKING SENSE: WEAKLY ELECTRIC FISH MODULATE SENSORY FEEDBACK VIA SOCIAL BEHAVIOR AND MOVEMENT
MAKING SENSE: WEAKLY ELECTRIC FISH MODULATE SENSORY FEEDBACK VIA SOCIAL BEHAVIOR AND MOVEMENT. This dissertation examines the role of social behavior and movement for the modulation of electrosensory feedback social grouping and movement can produce higher order modulations (termed `envelopes'), which can have
Efficient weakly-radiative wireless energy transfer: An EIT-like approach
of renewable energy, energy storage and management, etc. In particular, there is a substantial recent interest [15] in enabling efficient and safe wireless energy transfer, motivated by the increased 0003Efficient weakly-radiative wireless energy transfer: An EIT-like approach Rafif E. Hamam
Quantifying changes in weak layer microstructure associated with artificial load changes
Marshall, Hans-Peter
a,b, , Karl Birkeland a,c , Hans-Peter Marshall d,e a Department of Earth Sciences, Montana State a compression test at a micro-scale, the force required for the SMP to rupture individual structures as well blocks of snow. A decrease in observed rupture frequency within the weak layer (or an increase
Pugh, Mary
THE LUBRICATION APPROXIMATION FOR THIN VISCOUS FILMS: REGULARITY AND LONG TIME BEHAVIOR OF WEAK = - Â· (f(h) h) in one space dimension. This equation, derived from a `lubrication approximation', models from a `lubrication approximation', models surface tension dominated motion of thin viscous films
Pugh, Mary
THE LUBRICATION APPROXIMATION FOR THIN VISCOUS FILMS: REGULARITY AND LONG TIME BEHAVIOR OF WEAK t = -# Â· (f(h)##h) in one space dimension. This equation, derived from a `lubrication approximation', models. This equation, derived from a `lubrication approximation', models surface tension dominated motion of thin
Lemmon, Michael
a part of microgrids, are incorporated to improve power quality and reliability when disruptions happen of microgrids [13], together with oth- er generation, storage and load units. These microgrid- s are installedVoltage Stability and Frequency Synchronization of Weak Power Distribution Networks with Inverter
On the notion of laminar and weakly turbulent elementary fluid flows: a simple mathematical model
Gianluca Argentini
2006-08-28
An elementary analytical fluid flow is composed by a geometric domain, a list of analytical constraints and by the function which depends on the physical properties, as Reynolds number, of the considered fluid. For this object, notions of laminar or weakly turbulent behavior are described using a simple mathematical model.
parameter mismatch when cooling down the sample from the graphene preparation temperature to the measurement to the preparation conditions. All these effects are consistent with initial growth and subsequent pining of grapheneLocal deformations and incommensurability of high quality epitaxial graphene on a weakly
Systematic Derivation of the Weakly Non-Linear Theory of Thermoacoustic Devices
Eindhoven, Technische Universiteit
Systematic Derivation of the Weakly Non-Linear Theory of Thermoacoustic Devices P.H.M.W. in 't Eindhoven P.O. Box 513, 5600 MB Eindhoven, The Netherlands Abstract Thermoacoustics is the field concerned of thermoacoustic devices: the ther- moacoustic prime mover and the thermoacoustic heat pump or refrigerator. Two
Weak Data Secrecy via Obfuscation in Network Coding Based Content Distribution
Battiti, Roberto
Weak Data Secrecy via Obfuscation in Network Coding Based Content Distribution Roberto G. Cascella of California Los Angeles, 3732F Boelter Hall, CA 90095 Los Angeles Email: {cascella, crispo, battiti in terms of error/loss protection and faster dissemination at the cost of exposing the data to intermediate
Applied Radiation and Isotopes 64 (2006) 6062 Weak energy dependence of EBT gafchromic film dose
Yu, Peter K.N.
2006-01-01
Applied Radiation and Isotopes 64 (2006) 6062 Weak energy dependence of EBT gafchromic film dose to megavoltage X-rays. The film is auto-developing and sensitive, it provides accurate dose assessment of low; Gafchromic EBT; Radiation dosimetry; Energy dependence; Dose response 1. Introduction In medical radiotherapy
UNUSUALLY WEAK DIFFUSE INTERSTELLAR BANDS TOWARD HD 62542 Theodore P. Snow,1
McCall, Benjamin J.
UNUSUALLY WEAK DIFFUSE INTERSTELLAR BANDS TOWARD HD 62542 Theodore P. Snow,1 Daniel E. Welty,2 approaches were made to the task of identifying the carriers (see Herbig 1995 or Snow 1995, 2001 for recent conclusions (Snow, York, & Welty 1977). With the advent of electronic detec- tors in the 1970s, however
QCD Corrections to Vector Boson Pair Production via Weak Boson Fusion
B. Jager; C. Oleari; D. Zeppenfeld
2006-08-24
NLO-QCD corrections to vector boson pair production via weak boson fusion have recently been calculated and implemented into flexible parton-level Monte-Carlo programs. These allow for the computation of cross sections and kinematical distributions within realistic experimental cuts. We summarize the basic elements of the calculation and review phenomenological results for the LHC.
A dropped cellphone call is a common frustration often caused by a weak
Herr, Hugh
A dropped cellphone call is a common frustration often caused by a weak signal or a strong to smaller, lighter, less- powered platforms. In order for small-platform sensors to detect low-level RF signals effec- tively, they must have high dynamic range, be small and light, consume little power
Lemmon, Michael
Stability analysis of weak rural electrification microgrids with droop-controlled rotational--Droop-controlled distributed generation (DG) units are widely used in microgrids for rural electrification applica- tions. In these microgrids, power quality is vulnerable to voltage and frequency instabilities due to limited generation
Exploring the Environmental Preference of Weak Interactions in ( / )8 Barrel Proteins
Babu, M. Madan
Exploring the Environmental Preference of Weak Interactions in ( / )8 Barrel Proteins S interactions, in a data set containing 71 nonredundant ( / )8 barrel proteins, with re- spect to amino acid of the protein; (e) majority of the interactions involve long-range con- tacts; (f) the preference of Arg
LEBESGUE-BOCHNER SPACES, DECOMPOSABLE SETS AND STRONG WEAKLY COMPACT GENERATION
RodrÃguez, JosÃ©
LEBESGUE-BOCHNER SPACES, DECOMPOSABLE SETS AND STRONG WEAKLY COMPACT GENERATION SEBASTIÂ´AN LAJARA is strongly reflexive (resp. super-reflexive) generated if, and only if, there exist a reflexive (resp. super Let X be a Banach space and let BX be its closed unit ball. We say that X is strongly generated
Weak -nets and interval chains Noga Alon, Haim Kaplan, Gabriel Nivasch1
Shamir, Ron
Weak -nets and interval chains Noga Alon, Haim Kaplan, Gabriel Nivasch1 , Micha Sharir, Shakhar@post.tau.ac.il, gnivasch@post.tau.ac.il, michas@post.tau.ac.il, shakhar@courant.nyu.edu. Noga Alon, Haim Kaplan, GabrielMINERVA Center for Geometry at Tel Aviv University. Work by Haim Kaplan was partially supported by ISF Grant 975
The full weak charge density distribution of 48Ca from parity violating electron scattering
Lin, Z
2015-01-01
Background: The ground state neutron density of a medium mass nucleus contains fundamental nuclear structure information and is at present relatively poorly known. Purpose: We explore if parity violating elastic electron scattering can provide a feasible and model independent way to determine not just the neutron radius but the full radial shape of the neutron density $\\rho_n(r)$ and the weak charge density $\\rho_W(r)$ of a nucleus. Methods: We expand the weak charge density of $^{48}$Ca in a model independent Fourier Bessel series and calculate the statistical errors in the individual coefficients that might be obtainable in a model parity violating electron scattering experiment. Results: We find that it is feasible to determine roughly six Fourier Bessel coefficients of the weak charge density of 48Ca within a reasonable amount of beam time. However, it would likely be much harder to determine the full weak density of a significantly heavier nucleus such as 208Pb. Conclusions: Parity violating elastic elec...
ELECTRICAL STIMULATION REDUCES AGE RELATED ATROPHY AND WEAKNESS IN EDL MUSCLES OF RATS
Dennis, Robert G.
the atrophy and weakness. We electrically stimulated EDL muscles of adult and old rats during a 2 month period of denervation. The control muscles of old rats had declines in muscle mass and maximum force compared with adult control muscles. Denervated muscles of either adult or old rats had even larger declines. Stimulated
Evolving a robust signal transduction pathway from weak cross-talk
Siryaporn, Albert
We have evolved a robust two-component signal transduction pathway from a sensor kinase (SK) and non-partner response regulator (RR) that show weak cross-talk in vitro and no detectable cross-talk in vivo in wild-type ...
Weakly Dispersive Hydraulic Flows in a Contraction -Parametric Solutions and Linear Stability
Ee, Bernard Kuowei
Weakly Dispersive Hydraulic Flows in a Contraction - Parametric Solutions and Linear Stability typically results is a transition of flow characteristics within the contraction yielding hydraulic flows of the contraction. As considered here, a hydraulic solution is generally one where the fluid response is a function
Evolving a robust signal transduction pathway from weak cross-talk
Siryaporn, Albert
We have evolved a robust two?component signal transduction pathway from a sensor kinase (SK) and non?partner response regulator (RR) that show weak cross?talk in vitro and no detectable cross?talk in vivo in wild?type ...
Field theory and weak Euler-Lagrange equation for classical particle-field systems
Hong Qin; J. W. Burby; Ronald C. Davidson
2015-04-17
It is commonly believed as a fundamental principle that energy-momentum conservation of a physical system is the result of space-time symmetry. However, for classical particle-field systems, e.g., charged particles interacting through self-consistent electromagnetic or electrostatic fields, such a connection has only been cautiously suggested. It has not been formally established. The difficulty is due to the fact that the dynamics of particles and the electromagnetic fields reside on different manifolds. We show how to overcome this difficulty and establish the connection by generalizing the Euler-Lagrange equation, the central component of a field theory, to a so-called weak form. The weak Euler-Lagrange equation induces a new type of flux, called the weak Euler-Lagrange current, which enters conservation laws. Using field theory together with the weak Euler-Lagrange equation developed here, energy-momentum conservation laws that are difficult to find otherwise can be systematically derived from the underlying space-time symmetry.
Weak Temperature Dependence of the Free Energy Surface and Folding Pathways of Structured Peptides
Caflisch, Amedeo
Weak Temperature Dependence of the Free Energy Surface and Folding Pathways of Structured Peptides a thermodynamic description of minima and transi- tion states on the free energy surface, which is determined near equilibrium by counting popula- tions. The free energy surface, plotted as a function of two-order parameters
Coating Flows of Non-Newtonian Fluids: Weakly and Strongly Elastic Limits
is on viscoelastic effects on single roll coating at low dimensionless speeds, although the analytical results weCoating Flows of Non-Newtonian Fluids: Weakly and Strongly Elastic Limits J. Ashmore(1,a), A February 2007 Abstract. We present an asymptotic analysis of the thickness of the liquid film that coats
CP Violation in Bs J/ decays at LHCb and Sensitivity to the Weak Mixing Phase s
Edinburgh, University of
both a quantitative and qualitative improvement in the precision with which s is obtained to the Weak Mixing Phase s Author: Colin David MCLEAN THESIS SUBMITTED IN FULFILLMENT OF THE REQUIREMENTS of the Bs J/ decay channel at LHCb. I hereby declare that the writing of this thesis is my own work
APS 2013 W.K.H Panofsky Prize 1 The Search for Weakly Interacting
California at Berkeley, University of
for physics beyond standard model! Tev scale or totally different origin? #12;B.Sadoulet APS 2013 WB.Sadoulet APS 2013 W.K.H Panofsky Prize 1 The Search for Weakly Interacting Massive Particle Dark Matter Science motivations and strategies Is dark matter made of particles? What physics? Complementarity
A weakness in Sun-Chen-Hwang's three-party key agreement protocols using passwords
International Association for Cryptologic Research (IACR)
A weakness in Sun-Chen-Hwang's three-party key agreement protocols using passwords Junghyun Nam Cheoncheon-dong, Jangan-gu, Suwon-si, Gyeonggi-do 440-746, Republic of Korea Abstract Recently, Sun, Chen. In this paper, we show that both of Sun-Chen-Hwang's protocols are insecure against an active adversary who can
Introduction Weakly electric fish (Fig.1A) have been a leading model system
Bustamante, Fabián E.
2501 Introduction Weakly electric fish (Fig.1A) have been a leading model system within sensory, cockroaches and fish, among others (Chiel et al., 2009; Nishikawa et al., 2007; Cowan and Fortune, 2007 fish including the African mormyrids. The mechanics exhibited by mormyrids differs greatly from
Carbon Lock-in Through Capital Stock Inertia Associated with Weak Near-term Climate Policies
Bertram, Christoph; Johnson, Nils; Luderer, Gunnar; Riahi, Keywan; Isaac, Morna; Eom, Jiyong
2015-01-01
Stringent long-term climate targets necessitate a strict limit on cumulative emissions in this century for which sufficient policy signals are so far lacking. Based on an ensemble of ten energy-economy models, we explore how long-term transformation pathways depend on policies pursued during the next two decades. We find that weak GHG emission targets for 2030 lead, in that year alone, to excess carbon dioxide emissions of nearly half of the annual emissions in 2010, mainly through coal electricity generation. Furthermore, by consuming more of the long-term cumulative emissions budget in the first two decades, weak policy increases the likelihood of overshooting the budget and the urgency of reducing GHG emissions. Therefore, to be successful under weak policies, models must prematurely retire much of the additional coal capacity post-2030 and remove large quantities of carbon dioxide from the atmosphere in the latter half of the century. While increased energy efficiency lowers mitigation costs considerably, even with weak near-term policies, it does not substantially reduce the short term reliance on coal electricity. However, increased energy efficiency does allow the energy system more flexibility in mitigating emissions and, thus, makes the post-2030 transition easier.
Precision of electro--weak couplings of scalar leptoquarks at TESLA
Johannes Blümlein
2000-11-29
We investigate the potential to measure the electro-weak couplings of scalar leptoquarks $\\Phi_s$ at TESLA for energies in the range of $\\sqrt{s} \\simeq 1 \\TeV$ using the pair production process $e^+e^- \\to \\Phi_s \\bar{\\Phi}_s$.
The role of strong and weak ties in Facebook: a community structure perspective
Ferrara, Emilio
The role of strong and weak ties in Facebook: a community structure perspective Emilio Ferrara of the well-known Facebook network. In particular, we discuss the quantitative assessment of the strength-scale online social network such as Facebook. Complex networks, Social network analysis, Community structure
On Facebook, Most Ties are Weak The emergence of pervasive socio-technical networks brings new
Ferrara, Emilio
On Facebook, Most Ties are Weak Abstract The emergence of pervasive socio-technical networks brings's theory can be extended to online social networks like Facebook, suggesting to use interaction data requires knowledge of the topology of the social network, e.g., who is friend with whom on Facebook. Our
Numerical Modeling of Hydro-acoustic Waves In Weakly Compressible Fluid Ali Abdolali1,2
Kirby, James T.
Numerical Modeling of Hydro-acoustic Waves In Weakly Compressible Fluid Ali Abdolali1,2 , James T of Civil Engineering, University of Roma Tre Low-frequency hydro-acoustic waves are precursors of tsunamis. Detection of hydro-acoustic waves generated due to the water column compression triggered by sudden seabed
Kawasaki, Masashi
Emergence of temporal-pattern sensitive neurons in the midbrain of weakly electric fish Gymnarchus fish, Gymnarchus niloticus, to two stimulus parameters that are critical for its behavior the jamming frequencies of fish's own electric organ and that of a neighbor's. The second parameter is the spatial
Derived equivalence classi cation of weakly symmetric algebras of Euclidean type
Holm, Thorsten
is isomorphic to its top P= rad P . The classical examples of sel#12;njective algebras (respectively, symmetricDerived equivalence classi#12;cation of weakly symmetric algebras of Euclidean type Rafa l Bocian Copernicus University, Chopina 12/18, 87-100 Toru#19;n, Poland b Institut fur Algebra und Geometrie, Fakult
Band, Yehuda B.
T-shaped quantum wires in magnetic fields: Weakly confined magnetoexcitons beyond the diamagnetic at vanishing magnetic field26 to B 0. Exciton states for interacting electron-hole pairs confined to a T-particle states confined to the T intersection in a magnetic field and then using these single- particle states
Limits on weak magnetic confinement of neutral atoms C. A. Sackett*
Sackett, Cass
Limits on weak magnetic confinement of neutral atoms C. A. Sackett* Physics Department, University It is shown that when a magnetic field is used to support neutral atoms against the gravitational force mg, the total curvature of the field magnitude B must be larger than m2 g2 / 2 2 B , where is the magnetic
Global weak solutions to magnetic fluid flows with nonlinear Maxwell-Cattaneo heat transfer law
Boyer, Edmond
Global weak solutions to magnetic fluid flows with nonlinear Maxwell-Cattaneo heat transfer law F transfer in a magnetic fluid flow under the action of an applied magnetic field. Instead of the usual heat-Cattaneo law, heat transfer, magnetic field, magnetization AMS subject classifications: 76N10, 35Q35. 1
Structural Weaknesses in the Open Smart Grid Protocol Klaus Kursawe Christiane Peters
International Association for Cryptologic Research (IACR)
Structural Weaknesses in the Open Smart Grid Protocol Klaus Kursawe Christiane Peters European The Open Smart Grid Protocol (OSGP) is currently deployed in various countries in large-scale Smart, a smart meter can also give input to grid control algorithms, be used for electricity markets, communicate
Directed Polymers in Random Environment are Diffusive at Weak Francis COMETS 2
Directed Polymers in Random Environment are Diffusive at Weak Disorder 1 Francis COMETS 2 Universit8502, Japan. email: nobuo@math.kyotou.ac.jp Abstract In this paper, we consider directed polymers in random and temperature), we prove monotonicity of the phase diagram in the temperature. Les Polym`eres Dirig'es En Milieu
Weak turbulence and collapses in the Majda-McLaughlin-Tabak equation: Fluxes in
Biven, Laura J.
., New York, NY, 10002, USA Preprint submitted to Elsevier Preprint 28 February 2005 #12;[4][5]. Important cases of weak turbulence have been found in the dynamics of Langmuir waves in plasmas [6, with the existence of a small parameter, the nonlinear coupling is much smaller than the linear dispersive effects
A Chemical Potential "Battery" for Superfluid 4He Weak E. Hoskinson
Sato, Yuki
A Chemical Potential "Battery" for Superfluid 4He Weak Links E. Hoskinson , Y. Sato , K. Penanen, similar to a simple battery or voltage source for analogous superconducting devices. We describe here, indicates both the pres- sure P across the array, and fluid flow through it. If a small power W is applied
Yang, Jingsong; Campobasso, Nino; Biju, Mangatt P.; Fisher, Kelly; Pan, Xiao-Qing; Cottom, Josh; Galbraith, Sarah; Ho, Thau; Zhang, Hong; Hong, Xuan; Ward, Paris; Hofmann, Glenn; Siegfried, Brett; Zappacosta, Francesca; Washio, Yoshiaki; Cao, Ping; Qu, Junya; Bertrand, Sophie; Wang, Da-Yuan; Head, Martha S.; Li, Hu; Moores, Sheri; Lai, Zhihong; Johanson, Kyung; Burton, George; Erickson-Miller, Connie; Simpson, Graham; Tummino, Peter; Copeland, Robert A.; Oliff, Allen
2014-10-02
c-Abl kinase activity is regulated by a unique mechanism involving the formation of an autoinhibited conformation in which the N-terminal myristoyl group binds intramolecularly to the myristoyl binding site on the kinase domain and induces the bending of the {alpha}I helix that creates a docking surface for the SH2 domain. Here, we report a small-molecule c-Abl activator, DPH, that displays potent enzymatic and cellular activity in stimulating c-Abl activation. Structural analyses indicate that DPH binds to the myristoyl binding site and prevents the formation of the bent conformation of the {alpha}I helix through steric hindrance, a mode of action distinct from the previously identified allosteric c-Abl inhibitor, GNF-2, that also binds to the myristoyl binding site. DPH represents the first cell-permeable, small-molecule tool compound for c-Abl activation.
The role of cooperative binding on noise expression
P. S. Gutierrez; D. Monteoliva; L. Diambra
2009-08-02
The origin of stochastic fluctuations in gene expression has received considerable attention recently. Fluctuations in gene expression are particularly pronounced in cellular systems because of the small copy number of species undergoing transitions between discrete chemical states and the small size of biological compartments. In this paper, we propose a stochastic model for gene expression regulation including several binding sites, considering elementary reactions only. The model is used to investigate the role of cooperativity on the intrinsic fluctuations of gene expression, by means of master equation formalism. We found that the Hill coefficient and the level of noise increases as the interaction energy between activators increases. Additionally, we show that the model allows to distinguish between two cooperative binding mechanisms.
Improved value for the silicon free exciton binding energy
Green, Martin A., E-mail: m.green@unsw.edu.au [Australian Centre for Advanced Photovoltaics, School of Photovoltaic and Renewable Energy Engineering, University of New South Wales, Sydney, Australia 2052 (Australia)
2013-11-15
The free exciton binding energy is a key parameter in silicon material and device physics. In particular, it provides the necessary link between the energy threshold for valence to conduction band optical absorption and the bandgap determining electronic properties. The long accepted low temperature binding energy value of 14.7 ± 0.4 meV is reassessed taking advantage of developments subsequent to its original determination, leading to the conclusion that this value is definitely an underestimate. Using three largely independent experimental data sets, an improved low temperature value of 15.01 ± 0.06 meV is deduced, in good agreement with the most comprehensive theoretical calculations to date.
Syntheses and DNA binding of new cationic porphyrintetrapeptide conjugates Gbor Mez a
Langowski, Jörg
shifts and hypochromicities. Decomposition of absorption spectra suggested the formation of two of di- and tricationic porphyrins bind to DNA by two distinct binding modes which can be identi ed agents [6,7]. The binding of cationic porphyrin derivatives to nucleic acids has been the subject
Promiscuous binding of extracellular peptides to cell surface class I MHC protein
Eisen, Herman N.
Algorithms derived from measurements of short-peptide (8–10 mers) binding to class I MHC proteins suggest that the binding groove of a class I MHC protein, such as K[superscript b], can bind well over 1 million different ...
SFmap: a web server for motif analysis and prediction of splicing factor binding sites
Mandel-Gutfreund, Yael
SFmap: a web server for motif analysis and prediction of splicing factor binding sites Inbal Paz1) that bind to sequence elements on the RNA. SFmap is a web server for predicting putative SF binding sites by the user. SFmap results are provided both as a text file and as a graphical web interface. INTRODUCTION
Theory of Free Energy and Entropy in Noncovalent Binding Huan-Xiang Zhou*,
Weston, Ken
Theory of Free Energy and Entropy in Noncovalent Binding Huan-Xiang Zhou*, and Michael K. Gilson, Rockville, Maryland 20850 Received December 23, 2008 Contents 1. Introduction 4092 2. Free Energy, Partition.4. Solvation and a Temperature-Dependent Energy Function 4096 3. Binding Free Energy and Binding Constant 4096
Metal binding in proteins: machine learning complements X-ray absorption spectroscopy
Passerini, Andrea
Metal binding in proteins: machine learning complements X-ray absorption spectroscopy Marco Lippi1 for the identification of metalloproteins and metal binding sites on a genome scale. An extensive evaluation conducted in combination with X- ray absorption spectroscopy shows the great potentiality of the approach. 1 Metal binding
Caflisch, Amedeo
Efficient Evaluation of Binding Free Energy Using Continuum Electrostatics Solvation Danzhi Huang of the absolute free energy of binding. A predictive accuracy of about 1.0 kcal/mol is obtained for 13 and 29 into proteins of known structure require fast and accurate methods for the evaluation of binding free energies.1
Non-binding of Flavor-Singlet Hadrons to Nuclei
Glennys R. Farrar; Gabrijela Zaharijas
2003-02-20
Strongly attractive color forces in the flavor singlet channel may lead to a stable H dibaryon. Here we show that an H or other compact, flavor singlet hadron is unlikely to bind to nuclei, so that bounds on exotic isotopes do not exclude their stability. Remarkably, a stable H appears to evade other experimental constraints as well, when account is taken of its expected compact spatial wavefunction.
Reversible Acid Gas Capture Using CO2-Binding Organic Liquids
Heldebrant, David J.; Koech, Phillip K.; Yonker, Clement R.; Rainbolt, James E.; Zheng, Feng
2010-08-31
Acid gas scrubbing technology is predominantly aqueous alkanolamine based. Of the acid gases, CO2, H2S and SO2 have been shown to be reversible, however there are serious disadvantages with corrosion and high regeneration costs. The primary scrubbing system composed of monoethanolamine is limited to 30% by weight because of the highly corrosive solution. This gravimetric limitation limits the CO2 volumetric (?108 g/L) and gravimetric capacity (?7 wt%) of the system. Furthermore the scrubbing system has a large energy penalty from pumping and heating the excess water required to dissolve the MEA bicarbonate salt. Considering the high specific heat of water (4 j/g-1K-1), low capacities and the high corrosion we set out to design a fully organic solvent that can chemically bind all acid gases i.e. CO2 as reversible alkylcarbonate ionic liquids or analogues thereof. Having a liquid acid gas carrier improves process economics because there is no need for excess solvent to pump and to heat. We have demonstrated illustrated in Figure 1, that CO2-binding organic liquids (CO2BOLs) have a high CO2 solubility paired with a much lower specific heat (<1.5 J/g-1K-1) than aqueous systems. CO2BOLs are a subsection of a larger class of materials known as Binding Organic Liquids (BOLs). Our BOLs have been shown to reversibly bind and release COS, CS2, and SO2, which we denote COSBOLS, CS2BOLs and SO2BOLs. Our BOLs are highly tunable and can be designed for post or pre-combustion gas capture. The design and testing of the next generation zwitterionic CO2BOLs and SO2BOLs are presented.
Synthesis and Characterization of Polyamine Bicycles for Anion Binding
Morehouse, Paula Kay
2007-10-09
,4,12,15,18,26,31,39-octaazapentacyclo [13.13.13.1.6,101.20,241.33,37] tetratetraconta-6, 7,9,20(43), 21,23,33(42),34,36-nonaene], N(CH2CH2NHCH2-m-xylyl-CH2NHCH2CH2)3N), 12, is readily capable of being protonated at the bridgehead amines. As a result it is also capable of binding anions...
High molecular weight polysaccharide that binds and inhibits virus
Konowalchuk, Thomas W
2014-01-14
This invention provides a high molecular weight polysaccharide capable of binding to and inhibiting virus and related pharmaceutical formulations and methods on inhibiting viral infectivity and/or pathogenicity, as well as immunogenic compositions. The invention further methods of inhibiting the growth of cancer cells and of ameliorating a symptom of aging. Additionally, the invention provides methods of detecting and/or quantifying and/or isolating viruses.
Bounds to binding energies from the concavity of thermodynamical functions
B. K. Jennings; B. R. Barrett; B. G. Giraud
2007-08-22
Sequences of experimental ground-state energies are mapped onto concave patterns cured from convexities due to pairing and/or shell effects. The same patterns, completed by a list of excitation energies, can be used to give numerical estimates of the grand potential $\\Omega(\\beta,\\mu)$ for a mixture of nuclei at low or moderate temperatures $T=\\beta^{-1}$ and at many chemical potentials $\\mu.$ The average nucleon number $(\\beta,\\mu)$ then becomes a continuous variable, allowing extrapolations towards nuclear masses closer to drip lines. We study the possible concavity of several thermodynamical functions, such as the free energy and the average energy, as functions of $.$ Concavity, when present in such functions, allows trivial interpolations and extrapolations providing upper and lower bounds, respectively, to binding energies. Such bounds define an error bar for the prediction of binding energies. An extrapolation scheme for such concave functions is tested. We conclude with numerical estimates of the binding energies of a few nuclei closer to drip lines.
Binding energy of the $X(3872)$ at unphysical pion masses
Baru, V; Filin, A A; Gegelia, J; Nefediev, A V
2015-01-01
Chiral extrapolation of the $X(3872)$ binding energy is investigated using the modified Weinberg formulation of chiral effective field theory for the $D \\bar{D}^*$ scattering. Given its explicit renormalisability, this approach is particularly useful to explore the interplay of the long- and short-range $D \\bar{D}^*$ forces in the $X(3872)$ from studying the light-quark (pion) mass dependence of its binding energy. In particular, the parameter-free leading-order calculation shows that the $X$-pole disappears for unphysical large pion masses. On the other hand, without contradicting the naive dimensional analysis, the higher-order pion-mass-dependent contact interaction can change the slope of the binding energy at the physical point yielding the opposite scenario of a stronger bound $X$ at pion masses larger than its physical value. An important role of the pion dynamics and of the 3-body $D\\bar{D}\\pi$ effects for chiral extrapolations of the $X$-pole is emphasised. The results of the present study should be ...
Gold Binding by Native and Chemically Modified Hops Biomasses
DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)
López, M. Laura; Gardea-Torresdey, J. L.; Peralta-Videa, J. R.; de la Rosa, G.; Armendáriz, V.; Herrera, I.; Troiani, H.; Henning, J.
2005-01-01
Heavy metals from mining, smelting operations and other industrial processing facilities pollute wastewaters worldwide. Extraction of metals from industrial effluents has been widely studied due to the economic advantages and the relative ease of technical implementation. Consequently, the search for new and improved methodologies for the recovery of gold has increased. In this particular research, the use of cone hops biomass ( Humulus lupulus ) was investigated as a new option for gold recovery. The results showed that the gold binding to native hops biomass was pH dependent from pH 2 to pH 6, with a maximum percentage bindingmore »at pH 3. Time dependency studies demonstrated that Au(III) binding to native and modified cone hops biomasses was found to be time independent at pH 2 while at pH 5, it was time dependent. Capacity experiments demonstrated that at pH 2, esterified hops biomass bound 33.4 mg Au/g of biomass, while native and hydrolyzed hops biomasses bound 28.2 and 12.0 mg Au/g of biomass, respectively. However, at pH 5 the binding capacities were 38.9, 37.8 and 11.4 mg of Au per gram of native, esterified and hydrolyzed hops biomasses, respectively. « less
GOTO, ATSUSHI
2012-01-01
Consumption in Relation to Sex Hormone–Binding Globulin andin Relation to Circulating Sex Hormone-binding GlobulinReferences 4. Genes in Sex Hormone Pathways and Diabetes
Paris 7 - Denis Diderot, Université
Transverse Shear Oscillator Investigation of Boundary Lubrication in Weakly Adhered Films J. Le received 16 October 2010; published 20 December 2010) We investigate the boundary lubrication in weakly, or lubrication. As the thickness of the thin film h is decreased down to a characteristic length scale relevant
Energy-Constrained Scheduling for Weakly-Hard Real-Time Systems Tarek A. AlEnawy and Hakan Aydin
Aydin, Hakan
a different type of problem. In the energy-constrained settings, the energy is more than an important designEnergy-Constrained Scheduling for Weakly-Hard Real-Time Systems Tarek A. AlEnawy and Hakan Aydin energy budget during an operation/mission. We adopt the weakly-hard real- time scheduling paradigm
Linear Boltzmann equation as the long time dynamics of an electron weakly coupled to a phonon eld
Linear Boltzmann equation as the long time dynamics of an electron weakly coupled to a phonon #12 that in the weak coupling limit the Wigner distribution of the electron density matrix converges to the solution of the linear Boltzmann equation globally in time. The collision kernel is identi#12;ed as the sum
A Continuous-State Coalescent and the Impact of Weak Selection on the Structure of Gene Genealogies
Adler, Fred
A Continuous-State Coalescent and the Impact of Weak Selection on the Structure of Gene Genealogies for understanding the shape of gene genealogies and resulting patterns of genetic diversity. However, the coalescent words: coalescent, weak selection, gene genealogies, interference,multisite selection. Researcharticle
Black, Carrie; Ng, C. S.
2013-01-15
It has been demonstrated that in the presence of weak collisions, described by the Lenard-Bernstein (LB) collision operator, the Landau-damped solutions become true eigenmodes of the system and constitute a complete set [C.-S. Ng et al., Phys. Rev. Lett. 83, 1974 (1999) and C. S. Ng et al., Phys. Rev. Lett. 96, 065002 (2004)]. We present numerical results from an Eulerian Vlasov code that incorporates the Lenard-Bernstein collision operator [A. Lenard and I. B. Bernstein, Phys. Rev. 112, 1456 (1958)]. The effect of collisions on the numerical recursion phenomenon seen in Vlasov codes is discussed. The code is benchmarked against exact linear eigenmode solutions in the presence of weak collisions, and a spectrum of Landau-damped solutions is determined within the limits of numerical resolution. Tests of the orthogonality and the completeness relation are presented.
An ultra-weak sector, the strong CP problem and the pseudo-Goldstone dilaton
DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)
Allison, Kyle; Hill, Christopher T.; Ross, Graham G.
2015-02-01
In the context of a Coleman–Weinberg mechanism for the Higgs boson mass, we address the strong CP problem. We show that a DFSZ-like invisible axion model with a gauge-singlet complex scalar field S, whose couplings to the Standard Model are naturally ultra-weak, can solve the strong CP problem and simultaneously generate acceptable electroweak symmetry breaking. The ultra-weak couplings of the singlet S are associated with underlying approximate shift symmetries that act as custodial symmetries and maintain technical naturalness. The model also contains a very light pseudo-Goldstone dilaton that is consistent with cosmological Polonyi bounds, and the axion can be themore »dark matter of the universe. We further outline how a SUSY version of this model, which may be required in the context of Grand Unification, can avoid introducing a hierarchy problem.« less
Symmetries of the triple degenerate DNLS equations for weakly nonlinear dispersive MHD waves
Webb, G. M.; Brio, M.; Zank, G. P.
1996-07-20
A formulation of Hamiltonian and Lagrangian variational principles, Lie point symmetries and conservation laws for the triple degenerate DNLS equations describing the propagation of weakly nonlinear dispersive MHD waves along the ambient magnetic field, in {beta}{approx}1 plasmas is given. The equations describe the interaction of the Alfven and magnetoacoustic modes near the triple umbilic point, where the fast magnetosonic, slow magnetosonic and Alfven speeds coincide and a{sub g}{sup 2}=V{sub A}{sup 2} where a{sub g} is the gas sound speed and V{sub A} is the Alfven speed. A discussion is given of the travelling wave similarity solutions of the equations, which include solitary wave and periodic traveling waves. Strongly compressible solutions indicate the necessity for the insertion of shocks in the flow, whereas weakly compressible, near Alfvenic solutions resemble similar, shock free travelling wave solutions of the DNLS equation.
Experimental Investigation of Weak Non-Mesonic Decay of 10Be(Lambda)Hypernuclei at CEBAF
S. Majewski; L. Majling; A. Margaryan; L. Tang
2005-08-05
Hypernuclei are convenient laboratory to study the baryon-baryon weak interaction and associated effective Hamiltonian. The strangeness changing process, in which a Lambda hyperon converts to a neutron with a release up to 176 MeV, provides a clear signal for a conversion of an s-quark to a d-quark. We propose to perform a non-mesonic weak decay study of 10Be(Lambda)hypernuclei using the (e,eK) reaction. These investigations will fully utilize the unique parameters of the CEBAF CW electron beam and RF system and are enabled by (1) the use of new detector for alpha particles based on the recently developed RF timing technique with picosecond resolution and (2) the small angle and large acceptance kaon spectrometer-HKS in Hall C.
Hemmerle, Arnaud; Charitat, Thierry; Lecuyer, Sigolène; Fragneto, Giovanna; Daillant, Jean; 10.1073/pnas.1211669109
2013-01-01
Understanding interactions between membranes requires measurements on well-controlled systems close to natural conditions, in which fluctuations play an important role. We have determined, by grazing incidence X-ray scattering, the interaction potential between two lipid bilayers, one adsorbed on a solid surface and the other floating close by. We find that interactions in this highly hydrated model system are two orders of magnitude softer than in previously reported work on multilayer stacks. This is attributed to the weak electrostatic repulsion due to the small fraction of ionized lipids in supported bilayers with a lower number of defects. Our data are consistent with the Poisson-Boltzmann theory, in the regime where repulsion is dominated by the entropy of counter ions. We also have unique access to very weak entropic repulsion potentials, which allowed us to discriminate between the various models proposed in the literature. We further demonstrate that the interaction potential between supported bilaye...
Conduction in low Mach number flows: Part I Linear & weakly nonlinear regimes
Lecoanet, Daniel; Zweibel, Ellen G; Burns, Keaton J; Oishi, Jeffrey S; Vasil, Geoffrey M
2014-01-01
Thermal conduction is an important energy transfer and damping mechanism in astrophysical flows. Fourier's law - the heat flux is proportional to the negative temperature gradient, leading to temperature diffusion - is a well-known empirical model of thermal conduction. However, entropy diffusion has emerged as an alternative thermal conduction model, despite not ensuring the monotonicity of entropy. This paper investigates the differences between temperature and entropy diffusion for both linear internal gravity waves and weakly nonlinear convection. In addition to simulating the two thermal conduction models with the fully compressible Navier-Stokes equations, we also study their effects in the reduced, "sound-proof" anelastic and pseudo-incompressible equations. We find that in the linear and weakly nonlinear regimes, temperature and entropy diffusion give quantitatively similar results, although there are some larger errors in the pseudo-incompressible equations with temperature diffusion due to inaccurac...
A Primer for Electro-Weak Induced Low Energy Nuclear Reactions
Y. N. Srivastava; A. Widom; L. Larsen
2008-10-01
In a series of papers, cited in the main body of the paper below, detailed calculations have been presented which show that electromagnetic and weak interactions can induce low energy nuclear reactions to occur with observable rates for a variety of processes. A common element in all these applications is that the electromagnetic energy stored in many relatively slow moving electrons can -under appropriate circumstances- be collectively transferred into fewer, much faster electrons with energies sufficient for the latter to combine with protons (or deuterons, if present) to produce neutrons via weak interactions. The produced neutrons can then initiate low energy nuclear reactions through further nuclear transmutations. The aim of this paper is to extend and enlarge upon various examples analyzed previously, present simplified order of magnitude estimates for each and to illuminate a common unifying theme amongst all of them.
Test of weak and strong factorization in nucleus-nucleuscollisions atseveral hundred MeV/nucleon
La Tessa, Chiara; Sihver, Lembit; Zeitlin, Cary; Miller, Jack; Guetersloh, Stephen; Heilbronn, Lawrence; Mancusi, Davide; Iwata,Yoshiuki; Murakami, Takeshi
2006-06-21
Total and partial charge-changing cross sections have been measured for argon projectiles at 400 MeV/nucleon in carbon, aluminum, copper, tin and lead targets; cross sections for hydrogen were also obtained, using a polyethylene target. The validity of weak and strong factorization properties has been investigated for partial charge-changing cross sections; preliminary cross section values obtained for carbon, neon and silicon at 290 and 400 MeV/nucleon and iron at 400 MeV/nucleon, in carbon, aluminum, copper, tin and lead targets have been also used for testing these properties. Two different analysis methods were applied and both indicated that these properties are valid, without any significant difference between weak and strong factorization. The factorization parameters have then been calculated and analyzed in order to find some systematic behavior useful for modeling purposes.
Forward Compton scattering with weak neutral current: Constraints from sum rules
DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)
Gorchtein, Mikhail; Zhang, Xilin
2015-07-01
We generalize forward real Compton amplitude to the case of the interference of the electromagnetic and weak neutral current, formulate a low-energy theorem, relate the new amplitudes to the interference structure functions and obtain a new set of sum rules. We address a possible new sum rule that relates the product of the axial charge and magnetic moment of the nucleon to the 0th moment of the structure function g?(?0). For the dispersive ? ?-box correction to the proton's weak charge, the application of the GDH sum rule allows us to reduce the uncertainty due to resonance contributions by amore »factor of two. The finite energy sum rule helps addressing the uncertainty in that calculation due to possible duality violations.« less
David J. Starling; P. Ben Dixon; Andrew N. Jordan; John C. Howell
2009-10-13
The amplification obtained using weak values is quantified through a detailed investigation of the signal to noise ratio for an optical beam deflection measurement. We show that for a given deflection, input power and beam radius, the use of interferometric weak values allows one to obtain the optimum signal to noise ratio using a coherent beam. This method has the advantage of reduced technical noise and allows for the use of detectors with a low saturation intensity. We report on an experiment which improves the signal to noise ratio for a beam deflection measurement by a factor of 54 when compared to a measurement using the same beam size and a quantum limited detector.
The Critical Curve of the Random Pinning and Copolymer Models at Weak Coupling
Quentin Berger; Francesco Caravenna; Julien Poisat; Rongfeng Sun; Nikos Zygouras
2013-06-19
We study random pinning and copolymer models, when the return distribution of the underlying renewal process has a polynomial tail with finite mean. We compute the asymptotic behavior of the critical curves of the models in the weak coupling regime, showing that it is universal. This proves a conjecture of Bolthausen, den Hollander and Opoku for copolymer models (ref. [8]), which we also extend to pinning models.
A spherically symmetric and stationary universe from a weak modification of general relativity
Christian Corda; Herman J. Mosquera Cuesta
2009-04-01
It is shown that a weak modification of general relativity, in the linearized approach, renders a spherically symmetric and stationary model of the universe. This is due to the presence of a third mode of polarization in the linearized gravity in which a "curvature" energy term is present. Such an energy can, in principle, be identified as the Dark Energy. The model can also help to a better understanding of the framework of the Einstein-Vlasov system.
Sources of contamination to weak lensing three-point statistics: constraints from N-body simulations
Elisabetta Semboloni; Catherine Heymans; Ludovic van Waerbeke; Peter Schneider
2008-02-27
We investigate the impact of the observed correlation between a galaxies shape and its surrounding density field on the measurement of third order weak lensing shear statistics. Using numerical simulations, we estimate the systematic error contribution to a measurement of the third order moment of the aperture mass statistic (GGG) from three-point intrinsic ellipticity correlations (III), and the three-point coupling between the weak lensing shear experienced by distant galaxies and the shape of foreground galaxies (GGI and GII). We find that third-order weak lensing statistics are typically more strongly contaminated by these physical systematics compared to second-order shear measurements, contaminating the measured three-point signal for moderately deep surveys with a median redshift z_m ~ 0.7 by ~ 15%. It has been shown that accurate photometric redshifts will be crucial to correct for this effect, once a model and the redshift dependence of the effect can be accurately constrained. To this end we provide redshift-dependent fitting functions to our results and propose a new tool for the observational study of intrinsic galaxy alignments. For a shallow survey with z_m ~ 0.4 we find III to be an order of magnitude larger than the expected cosmological GGG shear signal. Compared to the two-point intrinsic ellipticity correlation which is similar in amplitude to the two-point shear signal at these survey depths, third order statistics therefore offer a promising new way to constrain models of intrinsic galaxy alignments. Early shallow data from the next generation of very wide weak lensing surveys will be optimal for this type of study.
Next-to-leading order QCD corrections to photon production via weak-boson fusion
B. Jager
2010-04-06
We present a calculation of next-to-leading order QCD corrections to gamma jj production via weak-boson fusion at a hadron collider in the form of a flexible parton-level Monte Carlo program which allows us to study cross sections and distributions within experimentally relevant selection cuts. The radiative corrections are found to be moderate with residual scale uncertainties being considerably improved beyond tree level. The sensitivity of the reaction to anomalous W+ W- gamma couplings is investigated.
Nuclear magnetic absorption line widths in weak magnetic fields with a Robinson oscillator
Flugum, Timothy Lee
1987-01-01
precession Effects of a weak transverse rotating field C. Nuclear Magnetic Relaxation Introduction The Boltzmann factor The longitudinal relaxation time, T, The transverse relaxation time. Tz Instrument Tq and magnetic field homogeneity requirements... the oscillating (effectively rotating) magnetic field, Bt, was used by Bloch in his pioneer "nuclear induction" NMR experiments using bulk matter. The nuclear induction method thus uses "crossed coils" with their axes both perpendicular to the strong, steady...
Relative contributions of the weak, main and fission-recycling r-process
S. Shibagaki; T. Kajino; G. J. Mathews; S. Chiba; S. Nishimura; G. Lorusso
2015-12-26
There has been a persistent conundrum in attempts to model the nucleosynthesis of heavy elements by rapid neutron capture (the $r$-process). Although the location of the abundance peaks near nuclear mass numbers 130 and 195 identify an environment of rapid neutron capture near closed nuclear shells, the abundances of elements just above and below those peaks are often underproduced by more than an order of magnitude in model calculations. At the same time there is a debate in the literature as to what degree the $r$-process elements are produced in supernovae or the mergers of binary neutron stars. In this paper we propose a novel solution to both problems. We demonstrate that the underproduction of elements above and below the $r$-process peaks characteristic in the main or weak $r$-process events (like magnetohydrodynamic jets or neutrino-driven winds in core-collapse supernovae) can be supplemented via fission fragment distributions from the recycling of material in a neutron-rich environment such as that encountered in neutron star mergers. In this paradigm, the abundance peaks themselves are well reproduced by a moderately neutron rich, main $r$-process environment such as that encountered in the magnetohydrodynamical jets in supernovae supplemented with a high-entropy, weakly neutron rich environment such as that encountered in the neutrino-driven-wind model to produce the lighter $r$-process isotopes. Moreover, we show that the relative contributions to the $r$-process abundances in both the solar-system and metal-poor stars from the weak, main, and fission-recycling environments required by this proposal are consistent with estimates of the relative Galactic event rates of core-collapse supernovae for the weak and main $r$-process and neutron star mergers for the fission-recycling $r$-process.
Relative contributions of the weak, main and fission-recycling r-process
S. Shibagaki; T. Kajino; G. J. Mathews; S. Chiba; S. Nishimura; G. Lorusso
2015-05-09
There has been a persistent conundrum in attempts to model the nucleosynthesis of heavy elements by rapid neutron capture (the $r$-process). Although the location of the abundance peaks near nuclear mass numbers 130 and 195 identify an environment of rapid neutron capture near closed nuclear shells, the abundances of elements just above and below those peaks are often underproduced by more than an order of magnitude in model calculations. At the same time there is a debate in the literature as to what degree the $r$-process elements are produced in supernovae or the mergers of binary neutron stars. In this paper we propose a novel solution to both problems. We demonstrate that the underproduction of elements above and below the $r$-process peaks characteristic in the main or weak $r$-process events (like magnetohydrodynamic jets or neutrino-driven winds in core-collapse supernovae) can be supplemented via fission fragment distributions from the recycling of material in a neutron-rich environment such as that encountered in neutron star mergers. In this paradigm, the abundance peaks themselves are well reproduced by a moderately neutron rich, main $r$-process environment such as that encountered in the magnetohydrodynamical jets in supernovae supplemented with a high-entropy, weakly neutron rich environment such as that encountered in the neutrino-driven-wind model to produce the lighter $r$-process isotopes. Moreover, we show that the relative contributions to the $r$-process abundances in both the solar-system and metal-poor stars from the weak, main, and fission-recycling environments required by this proposal are consistent with estimates of the relative Galactic event rates of core-collapse supernovae for the weak and main $r$-process and neutron star mergers for the fission-recycling $r$-process.
The effective description of non-strange hadrons low-energy electro-weak transitions
Bunatian, Gevorg G
2015-01-01
Starting with the general principles of global and local symmetries, the effective pion-nucleon lagrangian, essentially non-linear in pion field, to describe the non-strange hadrons low-energy electro-weak transitions is developed. We encounter no divergence summarizing properly all the infinite power series in pion field which occur in the course of treatment. Our consistent approach proves to be relevant in considering P-parity violation in pion-nucleon interactions.
CONDUCTION IN LOW MACH NUMBER FLOWS. I. LINEAR AND WEAKLY NONLINEAR REGIMES
Lecoanet, Daniel; Brown, Benjamin P.; Zweibel, Ellen G.; Burns, Keaton J.; Oishi, Jeffrey S.; Vasil, Geoffrey M.
2014-12-20
Thermal conduction is an important energy transfer and damping mechanism in astrophysical flows. Fourier's law, in which the heat flux is proportional to the negative temperature gradient, leading to temperature diffusion, is a well-known empirical model of thermal conduction. However, entropy diffusion has emerged as an alternative thermal conduction model, despite not ensuring the monotonicity of entropy. This paper investigates the differences between temperature and entropy diffusion for both linear internal gravity waves and weakly nonlinear convection. In addition to simulating the two thermal conduction models with the fully compressible Navier-Stokes equations, we also study their effects in the reduced ''soundproof'' anelastic and pseudoincompressible (PI) equations. We find that in the linear and weakly nonlinear regime, temperature and entropy diffusion give quantitatively similar results, although there are some larger errors in the PI equations with temperature diffusion due to inaccuracies in the equation of state. Extrapolating our weakly nonlinear results, we speculate that differences between temperature and entropy diffusion might become more important for strongly turbulent convection.
Ren, Jing; Xianyu, Zhong-Zhi; He, Hong-Jian E-mail: xianyuzhongzhi@gmail.com
2014-06-01
We study gravitational interaction of Higgs boson through the unique dimension-4 operator ?H{sup †}HR, with H the Higgs doublet and R the Ricci scalar curvature. We analyze the effect of this dimensionless nonminimal coupling ? on weak gauge boson scattering in both Jordan and Einstein frames. We explicitly establish the longitudinal-Goldstone equivalence theorem with nonzero ? coupling in both frames, and analyze the unitarity constraints. We study the ?-induced weak boson scattering cross sections at O(1?30) TeV scales, and propose to probe the Higgs-gravity coupling via weak boson scattering experiments at the LHC (14 TeV) and the next generation pp colliders (50-100 TeV). We further extend our study to Higgs inflation, and quantitatively derive the perturbative unitarity bounds via coupled channel analysis, under large field background at the inflation scale. We analyze the unitarity constraints on the parameter space in both the conventional Higgs inflation and the improved models in light of the recent BICEP2 data.
Qweak: First Direct Measurement of the Weak Charge of the Proton
Nuruzzaman, NFN
2014-04-01
The Qweak experiment at Hall C of Thomas Jefferson National Accelerator Facility has made the first direct measurement of the weak charge of the proton, QWp, through a precision measurement of the parity-violating asymmetry in elastic e-p scattering at low momentum transfer Q2= 0.025 (GeV/c)2 with incident electron beam energy of 1.155 GeV. The Qweak experiment, along with earlier results of parity violating elastic scattering experiments, is expected to determine the most precise value of QWp which is suppressed in the Standard Model. If this result is further combined with the 133Cs atomic parity violation (APV) measurement, significant constraints on the weak charge of the up quark, down quark, and neutron can be extracted. This data will also be used to determine the weak-mixing angle, sin2 ?W, with a relative uncertainty of < 0.5% that will provide a competitive measurement of the running of sin2 ?W to low Q2. An overview of the experiment and its results using the commissioning dataset, constituting approximately 4% of the data collected in the experiment, are reported here.
Planck Scale Physics, Gravi-Weak Unification and the Higgs Inflation
L. V. Laperashvili; H. B. Nielsen; B. G. Sidharth
2015-04-24
Starting with a theory of the discrete space-time at the Planck scale, we developed a Gravi-Weak Unification (GWU) - a $Spin(4,4)$-invariant model unified gravity with weak $SU(2)$ gauge and Higgs fields in the visible and invisible sectors of the Universe. Considering the Gravi-Weak symmetry breaking, we showed that the obtained sub-algebras contain the self-dual left-handed gravity in the OW, and the anti-self-dual right-handed gravity in the MW. Finally, at the low energy limit, we have only the Standard Model (SM) and the Einstein-Hilbert's gravity. The Froggatt-Nielsen's prediction of the top-quark and Higgs masses was given in the assumption that there exist two degenerate vacua in the SM. This prediction was improved by the next order calculations. We have developed a model of the Higgs Inflation using the GWU action. According to this inflationary model, a scalar field (inflaton) starts trapped from the "false vacuum" of the Universe at the Higgs field's VEV $v_2 \\sim 10^{18}$ GeV. The interaction between the ordinary and mirror Higgs fields $\\phi$ and $\\widetilde{\\phi}$ generates a Hybrid model by A.~Linde of the Higgs Inflation in our Universe.
Planck Scale Physics, Gravi-Weak Unification and the Higgs Inflation
Laperashvili, L V; Sidharth, B G
2015-01-01
Starting with a theory of the discrete space-time at the Planck scale, we developed a Gravi-Weak Unification (GWU) - a $Spin(4,4)$-invariant model unified gravity with weak $SU(2)$ gauge and Higgs fields in the visible and invisible sectors of the Universe. Considering the Gravi-Weak symmetry breaking, we showed that the obtained sub-algebras contain the self-dual left-handed gravity in the OW, and the anti-self-dual right-handed gravity in the MW. Finally, at the low energy limit, we have only the Standard Model (SM) and the Einstein-Hilbert's gravity. The Froggatt-Nielsen's prediction of the top-quark and Higgs masses was given in the assumption that there exist two degenerate vacua in the SM. This prediction was improved by the next order calculations. We have developed a model of the Higgs Inflation using the GWU action. According to this inflationary model, a scalar field (inflaton) starts trapped from the "false vacuum" of the Universe at the Higgs field's VEV $v_2 \\sim 10^{18}$ GeV. The interaction bet...
DNA-Binding Mechanism in Prokaryotic Partition Complex Formation
Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalent Bonding Low-Cost Ground8 GasDEVELOPMENTS E P I IT h itDNA-Binding
Vibrational Softening of a Protein on Ligand Binding
Balog, Erica [Semmelweis University, Budapest, Hungary; Perahia, David [Ecole Normale Superieure de Cachan, Cachan, France; Smith, Jeremy C [ORNL; Merzel, Franci [National Institute of Chemistry, Solvenia
2011-01-01
Neutron scattering experiments have demonstrated that binding of the cancer drug methotrexate softens the low-frequency vibrations of its target protein, dihydrofolate reductase (DHFR). Here, this softening is fully reproduced using atomic detail normal-mode analysis. Decomposition of the vibrational density of states demonstrates that the largest contributions arise from structural elements of DHFR critical to stability and function. Mode-projection analysis reveals an increase of the breathing-like character of the affected vibrational modes consistent with the experimentally observed increased adiabatic compressibility of the protein on complexation.
Towards engineering hormone-binding globulins as drug delivery agents
Chan, Wee Lee; Zhou, Aiwu; Read, Randy J.
2014-11-26
(2014) Towards Engineering Hormone-Binding Globulins as Drug Delivery Agents. PLoS ONE 9(11): e113402. doi:10.1371/journal.pone. 0113402 Editor: Ashley M. Buckle, Monash University, Australia Received: June 10, 2014 Accepted: October 24, 2014 Published... stock solution was prepared by dissolving lyophilised cortisol (Sigma Aldrich) in 80% ethanol to make a 500 mM solution, which was then diluted with water to make solutions of 20, 40 and 80 mM, with water being used as a negative control. Aliquots...
Hydroxyapatite-binding peptides for bone growth and inhibition
Bertozzi, Carolyn R. (Berkeley, CA); Song, Jie (Shrewsbury, MA); Lee, Seung-Wuk (Walnut Creek, CA)
2011-09-20
Hydroxyapatite (HA)-binding peptides are selected using combinatorial phage library display. Pseudo-repetitive consensus amino acid sequences possessing periodic hydroxyl side chains in every two or three amino acid sequences are obtained. These sequences resemble the (Gly-Pro-Hyp).sub.x repeat of human type I collagen, a major component of extracellular matrices of natural bone. A consistent presence of basic amino acid residues is also observed. The peptides are synthesized by the solid-phase synthetic method and then used for template-driven HA-mineralization. Microscopy reveal that the peptides template the growth of polycrystalline HA crystals .about.40 nm in size.
Climate change: Clinton affirms binding emissions reduction policy
Fairley, P.
1996-12-04
In Australia last month President Clinton called for an international agreement to negotiate {open_quotes}legally binding commitments to fight climate change.{close_quotes} His comments affirmed the line the Administration adopted in July and lent prominence to the effort to bring about a treaty by December 1997. Environmentalists welcomed Clinton`s comments, but industry response is divided. The Global Climate Coalition (Washington), of which CMA is a member, has tried to slow negotiations by questioning the scientific consensus on climate change and suggesting {open_quotes}serious damage to the American economy{close_quotes} could result from emissions reduction.
Functionalized polymers for binding to solutes in aqueous solutions
Smith, Barbara F.; Robison, Thomas W.
2006-11-21
A functionalized polymer for binding a dissolved molecule in an aqueous solution is presented. The polymer has a backbone polymer to which one or more functional groups are covalently linked. The backbone polymer can be such polymers as polyethylenimine, polyvinylamine, polyallylamine, and polypropylamine. These polymers are generally water-soluble, but can be insoluble when cross-linked. The functional group can be for example diol derivatives, polyol derivatives, thiol and dithiol derivatives, guest-host groups, affinity groups, beta-diphosphonic acids, and beta-diamides
Characterization of Selective Binding of Alkali Cations with Carboxylate
Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)
AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 OutreachProductswsicloudwsiclouddenDVA N C E D BGene Network ShapingDate:Characterization of Selective Binding of
Relativistic Nuclear Energy Density Functionals: adjusting parameters to binding energies
T. Niksic; D. Vretenar; P. Ring
2008-09-08
We study a particular class of relativistic nuclear energy density functionals in which only nucleon degrees of freedom are explicitly used in the construction of effective interaction terms. Short-distance (high-momentum) correlations, as well as intermediate and long-range dynamics, are encoded in the medium (nucleon density) dependence of the strength functionals of an effective interaction Lagrangian. Guided by the density dependence of microscopic nucleon self-energies in nuclear matter, a phenomenological ansatz for the density-dependent coupling functionals is accurately determined in self-consistent mean-field calculations of binding energies of a large set of axially deformed nuclei. The relationship between the nuclear matter volume, surface and symmetry energies, and the corresponding predictions for nuclear masses is analyzed in detail. The resulting best-fit parametrization of the nuclear energy density functional is further tested in calculations of properties of spherical and deformed medium-heavy and heavy nuclei, including binding energies, charge radii, deformation parameters, neutron skin thickness, and excitation energies of giant multipole resonances.
125 Gev Higgs-Boson as Scalar partner of 91 Gev $Z^{0}$-Weak-boson in Composite subquark model
Takeo Matsushima
2012-07-10
The composite subquark model previously proposed by us shows that the intermediate $Z^{0}$-weak-boson is realized as the composite particle and that its scalar partner has the mass value larger than $Z^{0}$-weak-boson mass. It is suggested that 125 Gev Higgs-boson found at LHC is a scalar partner of 91 Gev $Z^{0}$-weak-boson. We predict the existence of charged Higgs-bosons with the mass value around 100 to 120 Gev as the scalar partners of $W^{\\pm}$. We also discuss about Dark energy and Dark matter.
Francois Louchet
2015-04-07
Snow slab avalanche release usually results from failure of weak layers made of loose ice crystals. In previous field experiments, we evidenced for the first time an interesting stress-driven transition in the weak layer between a granular fluid and a solid phase. We propose here an original model involving the kinetics of ice grains bonds failure and reconstruction. The model evidences a sudden transition between two drastically different types of weak layer behaviors. It accounts for the characteristics of both the studied fluid-solid transition and for slab avalanche release observations. It may possibly apply to a number of other granular materials.
Binding of transcription factors adapts to resolve information-energy trade-off
Kagan, Yonatan Savir Jacob
2015-01-01
We examine the binding of transcription factors to DNA in terms of an information transfer problem. The input of the noisy channel is the biophysical signal of a factor bound to a DNA site, and the output is a distribution of probable DNA sequences at this site. This task involves an inherent tradeoff between the information gain and the energetics of the binding interaction - high binding energies provide higher information gain but hinder the dynamics of the system as factors are bound too tightly. We show that adaptation of the binding interaction towards increasing information transfer under energy constraints implies that the information gain per specific binding energy at each base-pair is maximized. We analyze hundreds of prokaryote and eukaryote transcription factors from various organisms to evaluate the discrimination energies. We find that, in accordance with our theoretical argument, binding energies nearly maximize the information gain per energy. This work suggests the adaptation of information ...
Evolutionary patterns of group B Sox binding and function in Drosophila
Carl, Sarah Hamilton
2015-04-07
ChIP-seq reads and input reads from three biological replicates in D. pseudoobscura . . . . . . . . . . . . . . . . . . . . 89 4.1 Reproducibility of biological replicate DamID samples . . . . . . . 97 4.2 Translated reads for Sox fusion proteins... ) is to bind DNA and regulate the expression of target genes; however, the complexity of combinatorial binding patterns and the sheer quantity of binding events, even in the model organism Drosophila, which has a smaller and more compact genome than hu- mans...
NOISY WEAK-LENSING CONVERGENCE PEAK STATISTICS NEAR CLUSTERS OF GALAXIES AND BEYOND
Fan Zuhui; Shan Huanyuan; Liu Jiayi
2010-08-20
Taking into account noise from intrinsic ellipticities of source galaxies, in this paper, we study the peak statistics in weak-lensing convergence maps around clusters of galaxies and beyond. We emphasize how the noise peak statistics is affected by the density distribution of nearby clusters, and also how cluster-peak signals are changed by the existence of noise. These are the important aspects to be thoroughly understood in weak-lensing analyses for individual clusters as well as in cosmological applications of weak-lensing cluster statistics. We adopt Gaussian smoothing with the smoothing scale {theta} {sub G} = 0.5arcmin in our analyses. It is found that the noise peak distribution near a cluster of galaxies sensitively depends on the density profile of the cluster. For a cored isothermal cluster with the core radius R{sub c} , the inner region with R {<=} R{sub c} appears noisy containing on average {approx}2.4 peaks with {nu} {>=} 5 for R{sub c} = 1.7arcmin and the true peak height of the cluster {nu} = 5.6, where {nu} denotes the convergence signal-to-noise ratio. For a Navarro-Frenk-White (NFW) cluster of the same mass and the same central {nu}, the average number of peaks with {nu} {>=} 5 within R {<=} R{sub c} is {approx}1.6. Thus a high peak corresponding to the main cluster can be identified more cleanly in the NFW case. In the outer region with R{sub c} < R {<=} 5R{sub c} , the number of high noise peaks is considerably enhanced in comparison with that of the pure noise case without the nearby cluster. For {nu} {>=} 4, depending on the treatment of the mass-sheet degeneracy in weak-lensing analyses, the enhancement factor f is in the range of {approx}5 to {approx}55 for both clusters as their outer density profiles are similar. The properties of the main-cluster-peak identified in convergence maps are also significantly affected by the presence of noise. Scatters as well as a systematic shift for the peak height are present. The height distribution is peaked at {nu} {approx} 6.6, rather than at {nu} = 5.6, corresponding to a shift of {Delta}{nu} {approx} 1, for the isothermal cluster. For the NFW cluster, {Delta}{nu} {approx} 0.8. The existence of noise also causes a location offset for the weak-lensing identified main-cluster-peak with respect to the true center of the cluster. The offset distribution is very broad and extends to R {approx} R{sub c} for the isothermal case. For the NFW cluster, it is relatively narrow and peaked at R {approx} 0.2R{sub c} . We also analyze NFW clusters of different concentrations. It is found that the more centrally concentrated the mass distribution of a cluster is, the less its weak-lensing signal is affected by noise. Incorporating these important effects and the mass function of NFW dark matter halos, we further present a model calculating the statistical abundances of total convergence peaks, true and false ones, over a large field beyond individual clusters. The results are in good agreement with those from numerical simulations. The model then allows us to probe cosmologies with the convergence peaks directly without the need of expensive follow-up observations to differentiate true and false peaks.
Tian, Guoxin
2013-01-01
binding strength and modes of uranyl complexes withand the coordination modes in the uranyl glutarimidedioximeof the bonding orbitals of uranyl (? u , ? g , ? u and ? g )
Jinglei Hu; Guang-Kui Xu; Reinhard Lipowsky; Thomas R. Weikl
2015-11-24
The adhesion of biological membranes is mediated by the binding of membrane-anchored receptor and ligand proteins. Central questions are how the binding kinetics of these proteins is affected by the membranes and by the membrane anchoring of the proteins. In this article, we (i) present detailed data for the binding of membrane-anchored proteins from coarse-grained molecular dynamics simulations, and (ii) provide a theory that describes how the binding kinetics depends on the average separation and thermal roughness of the adhering membranes, and on the anchoring, lengths, and length variations of the proteins. An important element of our theory is the tilt of bound receptor-ligand complexes and transition-state complexes relative to the membrane normals. This tilt results from an interplay of the anchoring energy and rotational entropy of the complexes and facilitates the formation of receptor-ligand bonds at membrane separations smaller than the preferred separation for binding. In our simulations, we have considered both lipid-anchored and transmembrane receptor and ligand proteins. We find that the binding equilibrium constant and binding on-rate constant of lipid-anchored proteins are considerably smaller than the binding constant and on-rate constant of rigid transmembrane proteins with identical binding domains.
Energy landscapes for protein folding, binding, and aggregation : simple funnels and beyond
Cho, Samuel Sung-Il
2007-01-01
coordinates capture protein folding on smooth landscapes.in the Prediction of Protein Folding Kinetics. Proc. Natl.Landscapes for Protein Folding, Binding, and Aggregation:
Binding Energies of the Alpha Particle and the A=3 Isobars from a Theoretical Geometric Model
Gustavo R. Gonzalez-Martin
2008-05-03
We assume a triple geometric structure for the electromagnetic nuclear interaction. This nuclear electromagnetism is used to calculate the binding energies of the alpha particle and the A=3 isobar nuclides. The approximation for the resultant wave equation which lead to the deuteron binding energy from the modified Mathieu equation for the radial eigenvalue equation also establishes proton-electron-proton magnetic bonds in these nuclides and determines their binding energies. Completely theoretical calculations give 28.5 Mev., 7.64 Mev. and 8.42 Mev. for the binding energies of the alpha particle, the helium 3 isotope and tritium respectively. These values admit correction factors due to the approximations made.
Tian, Guoxin
2013-01-01
data_request/cif. OECD, Uranium 2009: Resources, Productionthermodynamics of uranium”, (H. Wanner and I. Forest,of California. Sequestering uranium from seawater: binding
Analytic control methods for high fidelity unitary operations in a weakly nonlinear oscillator
J. M. Gambetta; F. Motzoi; S. T. Merkel; F. K. Wilhelm
2011-01-20
In qubits made from a weakly anharmonic oscillator the leading source of error at short gate times is leakage of population out of the two dimensional Hilbert space that forms the qubit. In this paper we develop a general scheme based on an adiabatic expansion to find pulse shapes that correct this type of error. We find a family of solutions that allows tailoring to what is practical to implement for a specific application. Our result contains and improves the previously developed DRAG technique [F. Motzoi, et. al., Phys. Rev. Lett. 103, 110501 (2009)] and allows a generalization to other non-linear oscillators with more than one leakage transition.
Crossover from weak to strong coupling regime in dispersive circuit QED
I. Serban; E. Solano; F. K. Wilhelm
2007-10-30
We study the decoherence of a superconducting qubit due to the dispersive coupling to a damped harmonic oscillator. We go beyond the weak qubit-oscillator coupling, which we associate with a phase Purcell effect, and enter into a strong coupling regime, with qualitatively different behavior of the dephasing rate. We identify and give a physicaly intuitive discussion of both decoherence mechanisms. Our results can be applied, with small adaptations, to a large variety of other physical systems, e. g. trapped ions and cavity QED, boosting theoretical and experimental decoherence studies.
Weak low-energy couplings from topological zero-mode wavefunctions
P. Hernandez; M. Laine; C. Pena; E. Torro; J. Wennekers; H. Wittig
2007-10-30
We discuss a new method to determine the low-energy couplings of the $\\Delta S=1$ weak Hamiltonian in the $\\epsilon$-regime. It relies on a matching of the topological poles in $1/m^2$ of three-point functions of two pseudoscalar densities and a four-fermion operator computed in lattice QCD, to the same observables in the Chiral Effective Theory. We present the results of a NLO computation in chiral perturbation theory of these correlation functions together with some preliminary numerical results.
A Lorentz-Poincaré type interpretation of the Weak Equivalence Principle
Jan; Broekaert
2007-03-22
The validity of the Weak Equivalence Principle relative to a local inertial frame is detailed in a scalar-vector gravitation model with Lorentz-Poincar\\'e type interpretation. Given the previously established first Post-Newtonian concordance of dynamics with General Relativity, the principle is to this order compatible with GRT. The gravitationally modified Lorentz transformations, on which the observations in physical coordinates depend, are shown to provide a physical interpretation of \\emph{parallel transport}. A development of ``geodesic'' deviation in terms of the present model is given as well.
Neutral weak-current two-body contributions in inclusive scattering from {sup 12}C
Lovato, Alessandro; Gandolfi, Stefano; Carlson, Joseph; Pieper, S. C.; Schiavilla, Rocco
2014-05-01
An {\\it ab initio} calculation of the sum rules of the neutral weak response functions in $^{12}$C is reported, based on a realistic Hamiltonian, including two- and three-nucleon potentials, and on realistic currents, consisting of one- and two-body terms. We find that the sum rules of the response functions associated with the longitudinal and transverse components of the (space-like) neutral current are largest and that a significant portion ($\\simeq 30$\\%) of the calculated strength is due to two-body terms. This fact may have implications for the MiniBooNE and other neutrino quasi-elastic scattering data on nuclei.
Testing the Standard Model by precision measurement of the weak charges of quarks
Ross Young; Roger Carlini; Anthony Thomas; Julie Roche
2007-05-01
In a global analysis of the latest parity-violating electron scattering measurements on nuclear targets, we demonstrate a significant improvement in the experimental knowledge of the weak neutral-current lepton-quark interactions at low-energy. The precision of this new result, combined with earlier atomic parity-violation measurements, limits the magnitude of possible contributions from physics beyond the Standard Model - setting a model-independent, lower-bound on the scale of new physics at ~1 TeV.
Effects of a weakly 3-D equilibrium on ideal magnetohydrodynamic instabilities
Hegna, C. C. [Departments of Engineering Physics and Physics, University of Wisconsin-Madison, Madison, Wisconsin 53706 (United States)
2014-07-15
The effect of a small three-dimensional equilibrium distortion on an otherwise axisymmetric configuration is shown to be destabilizing to ideal magnetohydrodynamic modes. The calculations assume that the 3-D fields are weak and that shielding physics is present so that no islands appear in the resulting equilibrium. An eigenfunction that has coupled harmonics of different toroidal mode number is constructed using a perturbation approach. The theory is applied to the case of tokamak H-modes with shielded resonant magnetic perturbations (RMPs) present indicating RMPs can be destabilizing to intermediate-n peeling-ballooning modes.
Sundar, Sita; Das, Amita; Kaw, Predhiman [Institute for Plasma Research, Bhat, Gandhinagar-382428 (India)
2012-05-15
In the interaction of intense lasers with matter/plasma, energetic electrons having relativistic energies get created. These energetic electrons can often have sheared flow profiles as they propagate through the plasma medium. In an earlier study [Phys. Plasmas 17, 022101 (2010)], it was shown that a relativistic sheared electron flow modifies the growth rate and threshold condition of the conventional Kelvin-Helmholtz instability. A perturbative analytic treatment for the case of weakly relativistic regime has been provided here. It provides good agreement with the numerical results obtained earlier.
Hobbs, D.; Elvington, M.; Click, D.
2009-11-11
Inorganic, titanate-based sorbents are tested with respect to adsorption of a variety of sorbates under weakly acidic conditions (pH 3). Specifically, monosodium titanate (MST) and amorphous peroxotitanate (APT) sorption characteristics are initially probed through a screening process consisting of a pair of mixed metal solutions containing a total of 29 sorbates including alkali metals, alkaline earth metals, transition metals, metalloids and nonmetals. MST and APT sorption characteristics are further analyzed individually with chromium(III) and cadmium(II) using a batch method at ambient laboratory temperature, varying concentrations of the sorbents and sorbates and contact times. Maximum sorbate loadings are obtained from the respective adsorption isotherms.
Dynamics of a charged particle around a weakly magnetized naked singularity
Gulmina Zaman Babar; Mubasher Jamil; Yen-Kheng Lim
2015-10-17
We examine the motion of a charged particle in the vicinity of a weakly magnetized naked singularity. The escape velocity and energy of the particle moving around the naked singularity after being kicked by another particle or photon are investigated. Also at the innermost stable circular orbit (ISCO) escape velocity and energy are examined. Effective potential and angular momentum of the particle are also discussed. We discuss the center of mass energy after collision between two particles having same mass and opposite charges moving along the same circular orbit in the opposite direction. It is investigated that under what conditions maximum energy can be produced as a result of collision.
Reversing the weak measurement of an arbitrary field with finite photon number
Sun, Qingqing; Al-Amri, M.; Zubairy, M. Suhail.
2009-01-01
?, can still be reversed probabilistically. If the photon de- tector registered k ?m?n?k? clicks during time t, the com- ponent ?n? will change into e??a? ?a?ta?k?n? = e???n?k?t n ! /?n ? k?!?n ? k? , ?11? where we have ignored the prefactor e???t1... efficiency of the reversing operation ?10?. In a recent experiment ?11?, based on a proposal by Korotkov and Jordan ?12?, the rever- sal of a weak measurement on a superconducting phase qubit was performed. A general procedure for N-dimensional sys- tem...
Doppler-Free Spectroscopy of Weak Transitions: An Analytical Model Applied to Formaldehyde
Zeppenfeld, M; Pinkse, P W H; Rempe, G
2007-01-01
Experimental observation of Doppler-free signals for weak transitions can be greatly facilitated by an estimate for the expected amplitude of the signal. We derive an analytical model which allows the Doppler-free signal amplitude to be estimated for small Doppler-free signals. Application of this model to formaldehyde allows the amplitude of experimentally observed Doppler-free signals to be reproduced to within a factor of two and the relative amplitude of different lines to be reproduced to within a few percent.
Global Solutions of Viscous Transonic Flows in Kerr Geometry I: Weak Viscosity Limit
Sandip K. Chakrabarti
1996-11-04
We present fully general relativistic equations governing viscous transonic flows in vertical equilibrium in Kerr geometry. We find the complete set of global solutions (both for Optically thick and optically thin flows) in the weak viscosity limit. We show that for a large region of parameter space, centrifugal pressure supported standing shocks can form in accretion and winds very close to the black hole horizon, both for co-rotating and contra-rotating flows. We compute the nature of the shear tensor for complete transonic solutions and discuss the consequences of its reversal properties.
Estimation of temporal separation of slow light pulses in atomic vapors by weak measurement
Pardeep Kumar; Shubhrangshu Dasgupta
2015-03-16
We show how two circular polarization components of a linearly polarized pulse, propagating through a coherently driven dilute atomic vapor, can be well resolved in time domain by weak measurement. Slower group velocity of one of the components due to electromagnetically induced transparency leads to a differential group delay between the two components. For low number density, this delay may not be large enough to temporally resolve the two components. We show how this can be enhanced in terms of mean time of arrival of the output pulse through a post-selected polarizer. We demonstrate the idea with all the analytical and numerical results, with a specific example of alkali atoms.
Field theory and weak Euler-Lagrange equation for classical particle-field systems
Qin, Hong; Burby, Joshua W; Davidson, Ronald C
2014-10-01
It is commonly believed that energy-momentum conservation is the result of space-time symmetry. However, for classical particle-field systems, e.g., Klimontovich-Maxwell and Klimontovich- Poisson systems, such a connection hasn't been formally established. The difficulty is due to the fact that particles and the electromagnetic fields reside on different manifolds. To establish the connection, the standard Euler-Lagrange equation needs to be generalized to a weak form. Using this technique, energy-momentum conservation laws that are difficult to find otherwise can be systematically derived.
Calculating work in weakly driving quantum master equations: backward and forward equations
Fei Liu
2015-06-28
We present a technical report that the two methods of calculating characteristic functions for the work distribution in the weakly driven quantum master equations are equivalent. One is obtained by the notion of quantum jump trajectory [Phys. Rev. E 89, 042122 (2014)], while the other is based on the two time energy measurements on the combined system and reservoir [Silaev, et al., Phys. Rev. E 90, 022103 (2014)]. They are indeed the backward and forward methods, respectively, which is very similar to the case of the Kolmogorov backward and forward equations in classical stochastic theory. The microscopic basis of the former method is also clarified.
Seyyedi, S A
2015-01-01
Fusion reactions with a weakly bound projectile are studied using the double-folding model along with a repulsive interaction modifying term. Using this modified potential, including nuclear matter incompressibility effects, the fusion reaction cross sections and suppression parameters are calculated for 9Be +209Bi,208Pb,29Si and 27Al reactions. The results show that applying these effects at energies near the Coulomb barrier improves the agreement between the calculated and experimental cross sections, and modifies the mean values of the suppression parameter.
S. A. Seyyedi; H. Golnarkar
2015-01-19
Fusion reactions with a weakly bound projectile are studied using the double-folding model along with a repulsive interaction modifying term. Using this modified potential, including nuclear matter incompressibility effects, the fusion reaction cross sections and suppression parameters are calculated for 9Be +209Bi,208Pb,29Si and 27Al reactions. The results show that applying these effects at energies near the Coulomb barrier improves the agreement between the calculated and experimental cross sections, and modifies the mean values of the suppression parameter.
Okura, Yuki; Futamase, Toshifumi E-mail: tof@astr.tohoku.ac.jp
2013-07-01
This is the third paper on the improvement of systematic errors in weak lensing analysis using an elliptical weight function, referred to as E-HOLICs. In previous papers, we succeeded in avoiding errors that depend on the ellipticity of the background image. In this paper, we investigate the systematic error that depends on the signal-to-noise ratio of the background image. We find that the origin of this error is the random count noise that comes from the Poisson noise of sky counts. The random count noise makes additional moments and centroid shift error, and those first-order effects are canceled in averaging, but the second-order effects are not canceled. We derive the formulae that correct this systematic error due to the random count noise in measuring the moments and ellipticity of the background image. The correction formulae obtained are expressed as combinations of complex moments of the image, and thus can correct the systematic errors caused by each object. We test their validity using a simulated image and find that the systematic error becomes less than 1% in the measured ellipticity for objects with an IMCAT significance threshold of {nu} {approx} 11.7.
Anderson, Adam J. (Adam Jonathan)
2015-01-01
Cosmological and astrophysical evidence indicates that 85% of the matter content of the universe is in the form of non-baryonic dark matter. A large number of experiments are currently undertaking searches for weakly-interacting ...
DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)
Christov, Ivan C.; Jordan, Pedro M.
2015-07-17
Errors in Morse and Ingard’s treatment of the topic of weakly-nonlinear acoustics in §6.2 of their book [Theoretical Acoustics (McGraw-Hill, New York, 1968)] are noted and corrected.
Completion for Weakly-supervised Multi-label Image Classification Ricardo Cabral, Fernando De la Torre, João segmentation. While efforts have been made to Ricardo Cabral is with the ECE Department, Carnegie Mellon Univer
Linear Boltzmann equation as the long time dynamics of an electron weakly coupled to a phonon field
Laszlo Erdos
2001-08-29
We consider the long time evolution of a quantum particle weakly interacting with a phonon field. We show that in the weak coupling limit the Wigner distribution of the electron density matrix converges to the solution of the linear Boltzmann equation globally in time. The collision kernel is identified as the sum of an emission and an absorption term that depend on the equilibrium distribution of the free phonon modes.
Mapping small molecule binding data to structural domains
Kruger, Felix A.; Rostom, Raghd; Overington, John P.
2012-12-07
R_lig-bind 25 128 P40238 fn3 391 475 P48443 Nuc_recep-AF1 24 134 P48443 Hormone_recep 248 443 P48443 zf-C4 137 206 P54219 MFS_1 77 433 P54219 MFS_1 422 493 Q92813 T4_deiodinase 4 262 P08506 PBP5_C 285 376 P08506 Peptidase_S11 28 266 P10826 Hormone_recep 222 406... P10826 zf-C4 86 155 P10828 Hormone_recep 257 445 P10828 zf-C4 105 176 P11926 Orn_Arg_deC_N 44 282 P11926 Orn_DAP_Arg_deC 285 408 P19793 Nuc_recep-AF1 16 127 P19793 Hormone_recep 251 442 P19793 zf-C4 133 202 P27815 PDEase_I 432 676 P28702 Hormone...
On the nuclear interaction. Potential, binding energy and fusion reaction
I. Casinos
2008-05-22
The nuclear interaction is responsible for keeping neutrons and protons joined in an atomic nucleus. Phenomenological nuclear potentials, fitted to experimental data, allow one to know about the nuclear behaviour with more or less success where quantum mechanics is hard to be used. A nuclear potential is suggested and an expression for the potential energy of two nuclear entities, either nuclei or nucleons, is developed. In order to estimate parameters in this expression, some nucleon additions to nuclei are considered and a model is suggested as a guide of the addition process. Coulomb barrier and energy for the addition of a proton to each one of several nuclei are estimated by taking into account both the nuclear and electrostatic components of energy. Studies on the binding energies of several nuclei and on the fusion reaction of two nuclei are carried out.
Development of Gamma-Emitting Receptor Binding Radiopharmace
Reba, Richard
2003-02-20
The long-term objective is to develop blood-brain barrier (BBB) permeable m2-selective (relative to m1, m3, and m4) receptor-binding radiotracers and utilize these radiotracers for quantifying receptor concentrations obtained from PET or SPECT images of human brain. In initial studies, we concluded that the lipophilicity and high affinity prevented (R,S)-I-QNB from reaching a flow-independent and receptor-dependent state in a reasonable time. Thus, it was clear that (R,S)-I-QNB should be modified. Therefore, during the last portion of this funded research, we proposed that more polar heterocycles should help accomplish that. Since reports of others concluded that radiobromination and radiofluorination of the unactivated phenyl ring is not feasible (Newkome et al,,1982), we, therefore, explored during this grant period a series of analogues of (R)-QNB in which one or both of the six-membered phenyl rings is replaced by a five-membered thienyl (Boulay et al., 1995), or furyl ring. The chemistry specific aims were to synthesize novel compounds designed to be m2-selective mAChR ligands capable of penetrating into the CNS, and develop methods for efficient radiolabeling of promising m2-selective muscarinic ligands. The pharmacology specific aims were to determine the affinity and subtype-selectivity of the novel compounds using competition binding studies with membranes from cells that express each of the five muscarinic receptor subtypes, to determine the ability of the promising non-radioactive compounds and radiolabeled novel compounds to cross the BBB, to determine the biodistribution, in-vivo pharmacokinetics, and in-vitm kinetics of promising m2-selective radioligands and to determine the distribution of receptors for the novel m2-selective radioligands using quantitative autoradiography of rat brain, and compare this distribution to the distribution of known m2-selective compounds.
Weak Values and Modular Variables From a Quantum Phase Space Perspective
Augusto C. Lobo; Yakir Aharonov; Jeff Tollaksen; Elizabeth M. Berrigan; Clyffe A. Ribeiro
2014-09-09
We address two major conceptual developments introduced by Aharonov and collaborators through a \\textit{quantum phase space} approach: the concept of \\textit{modular variables} devised to explain the phenomena of quantum dynamical non-locality and the \\textit{two-state formalism} for Quantum Mechanics which is a retrocausal time-symmetric interpretation of quantum physics which led to the discovery of \\textit{weak values.} We propose that a quantum phase space structure underlies these profound physical insights in a unifying manner. For this, we briefly review the Weyl-Wigner and the coherent state formalisms as well as the inherent symplectic structures of quantum projective spaces in order to gain a deeper understanding of the weak value concept. We also review Schwinger's finite quantum kinematics so that we may apply this discrete formalism to understand Aharonov's modular variable concept in a different manner that has been proposed before in the literature. We discuss why we believe that this\\ is indeed the correct kinematic framework for the modular variable concept and how this may shine some light on the physical distinction between quantum dynamical non-locality and the kinematic non-locality, generally associated with entangled quantum systems.
Lian-Ao Wu; Claire X. Yu; Dvira Segal
2012-07-30
We demonstrate an exact mapping of a class of models of two interacting qubits in thermal reservoirs to two separate spin-bath problems. Based on this mapping, exact numerical simulations of the qubits dynamics can be performed, beyond the weak system-bath coupling limit. Given the time evolution of the system, we study, in a numerically exact way, the dynamics of entanglement between pair of qubits immersed in boson thermal baths, showing a rich phenomenology, including an intermediate oscillatory behavior, the entanglement sudden birth, sudden death, and revival. We find that stationary entanglement develops between the qubits due to their coupling to a thermal environment, unlike the isolated qubits case in which the entanglement oscillates. We also show that the occurrence of entanglement sudden death in this model depends on the portion of the zero and double excitation states in the subsystem initial state. In the long-time limit, analytic expressions are presented at weak system-bath coupling, for a range of relevant qubit parameters.
The MOLLER Experiment: An Ultra-Precise Measurement of the Weak Mixing Angle Using Møller Scattering
MOLLER Collaboration; J. Benesch; P. Brindza; R. D. Carlini; J-P. Chen; E. Chudakov; S. Covrig; M. M. Dalton; A. Deur; D. Gaskell; A. Gavalya; J. Gomez; D. W. Higinbotham; C. Keppel; D. Meekins; R. Michaels; B. Moffit; Y. Roblin; R. Suleiman; R. Wines; B. Wojtsekhowski; G. Cates; D. Crabb; D. Day; K. Gnanvo; D. Keller; N. Liyanage; V. V. Nelyubin; H. Nguyen; B. Norum; K. Paschke; V. Sulkosky; J. Zhang; X. Zheng; J. Birchall; P. Blunden; M. T. W. Gericke; W. R. Falk; L. Lee; J. Mammei; S. A. Page; W. T. H. van Oers; K. Dehmelt; A. Deshpande; N. Feege; T. K. Hemmick; K. S. Kumar; T. Kutz; R. Miskimen; M. J. Ramsey-Musolf; S. Riordan; N. Hirlinger Saylor; J. Bessuille; E. Ihloff; J. Kelsey; S. Kowalski; R. Silwal; G. De Cataldo; R. De Leo; D. Di Bari; L. Lagamba; E. NappiV. Bellini; F. Mammoliti; F. Noto; M. L. Sperduto; C. M. Sutera; P. Cole; T. A. Forest; M. Khandekar; D. McNulty; K. Aulenbacher; S. Baunack; F. Maas; V. Tioukine; R. Gilman; K. Myers; R. Ransome; A. Tadepalli; R. Beniniwattha; R. Holmes; P. Souder; D. S. Armstrong; T. D. Averett; W. Deconinck; W. Duvall; A. Lee; M. L. Pitt; J. A. Dunne; D. Dutta; L. El Fassi; F. De Persio; F. Meddi; G. M. Urciuoli; E. Cisbani; C. Fanelli; F. Garibaldi; K. Johnston; N. Simicevic; S. Wells; P. M. King; J. Roche; J. Arrington; P. E. Reimer; G. Franklin; B. Quinn; A. Ahmidouch; S. Danagoulian; O. Glamazdin; R. Pomatsalyuk; R. Mammei; J. W. Martin; T. Holmstrom; J. Erler; Yu. G. Kolomensky; J. Napolitano; K. A. Aniol; W. D. Ramsay; E. Korkmaz; D. T. Spayde; F. Benmokhtar; A. Del Dotto; R. Perrino; S. Barkanova; A. Aleksejevs; J. Singh
2014-12-03
The physics case and an experimental overview of the MOLLER (Measurement Of a Lepton Lepton Electroweak Reaction) experiment at the 12 GeV upgraded Jefferson Lab are presented. A highlight of the Fundamental Symmetries subfield of the 2007 NSAC Long Range Plan was the SLAC E158 measurement of the parity-violating asymmetry $A_{PV}$ in polarized electron-electron (M{\\o}ller) scattering. The proposed MOLLER experiment will improve on this result by a factor of five, yielding the most precise measurement of the weak mixing angle at low or high energy anticipated over the next decade. This new result would be sensitive to the interference of the electromagnetic amplitude with new neutral current amplitudes as weak as $\\sim 10^{-3}\\cdot G_F$ from as yet undiscovered dynamics beyond the Standard Model. The resulting discovery reach is unmatched by any proposed experiment measuring a flavor- and CP-conserving process over the next decade, and yields a unique window to new physics at MeV and multi-TeV scales, complementary to direct searches at high energy colliders such as the Large Hadron Collider (LHC). The experiment takes advantage of the unique opportunity provided by the upgraded electron beam energy, luminosity, and stability at Jefferson Laboratory and the extensive experience accumulated in the community after a round of recent successfully completed parity-violating electron scattering experiments
Target Mass Corrections to Electro-Weak Structure Functions and Perturbative Neutrino Cross Sections
S. Kretzer; M. H. Reno
2003-11-14
We provide a complete and consistent framework to include subasymptotic perturbative as well as mass corrections to the leading twist (tau=2) evaluation of charged and neutral current weak structure functions and the perturbative neutrino cross sections. We revisit previous calculations in a modern language and fill in the gaps that we find missing for a complete and ready-to-use "NLO xi-scaling" formulary. In particular, as a new result we formulate the mixing of the partonic and hadronic structure function tensor basis in the operator approach to deep inelastic scattering. As an underlying framework we follow the operator product expansion a la Georgi & Politzer that allows the inclusion of target mass corrections at arbitrary order in QCD and we provide explicit analytical and numerical results at NLO. We compare this approach with a simpler collinear parton model approach to xi-scaling. Along with target mass corrections we include heavy quark mass effects as a calculable leading twist power suppressed correction. The complete corrections have been implemented into a Monte Carlo integration program to evaluate structure functions and/or integrated cross sections. As applications, we compare the operator approach with the collinear approximation numerically and we investigate the NLO and mass corrections to observables that are related to the extraction of the weak mixing angle from a Paschos-Wolfenstein-like relation in neutrino-iron scattering. We expect that the interpretation of neutrino scattering events in terms of oscillation physics and electroweak precision physics will benefit from our results.
Calibrating the Nonlinear Matter Power Spectrum: Requirements for Future Weak Lensing Surveys
Dragan Huterer; Masahiro Takada
2005-06-01
Uncertainties in predicting the nonlinear clustering of matter are among the most serious theoretical systematics facing the upcoming wide-field weak gravitational lensing surveys. We estimate the accuracy with which the matter power spectrum will need to be calibrated in order not to contribute appreciably to the error budget for future weak lensing surveys. We consider the random statistical errors and the systematic biases in P(k), as well as some estimates based on current N-body simulations. While the power spectrum on relevant scales (0.1 < k/h Mpc^{-1} < 10) is currently calibrated with N-body simulations to about 5-10%, in the future it will have to be calibrated to about 1-2% accuracy, depending on the specifications of the survey. Encouragingly, we find that even the worst-case error that mimics the effect of cosmological parameters needs to be calibrated to no better than about 0.5-1%. These goals require a suite of high resolution N-body simulations on a relatively fine grid in cosmological parameter space, and should be achievable in the near future.
Resonance reactions and enhancement of weak interactions in collisions of cold molecules
Flambaum, V. V.; Ginges, J. S. M. [School of Physics, University of New South Wales, Sydney 2052 (Australia)
2006-08-15
With the creation of ultracold atoms and molecules, a new type of chemistry - 'resonance' chemistry - emerges: chemical reactions can occur when the energy of colliding atoms and molecules matches a bound state of the combined molecule (Feshbach resonance). This chemistry is rather similar to reactions that take place in nuclei at low energies. In this paper we suggest some problems for future experimental and theoretical work related to the resonance chemistry of ultracold molecules. Molecular Bose-Einstein condensates are particularly interesting because in this system collisions and chemical reactions are extremely sensitive to weak fields; also, a preferred reaction channel may be enhanced due to a finite number of final states. The sensitivity to weak fields arises due to the high density of narrow compound resonances and the macroscopic number of molecules with kinetic energy E=0 (in the ground state of a mean-field potential). The high sensitivity to the magnetic field may be used to measure the distribution of energy intervals, widths, and magnetic moments of compound resonances and study the onset of quantum chaos. A difference in the production rate of right-handed and left-handed chiral molecules may be produced by external electric E and magnetic B fields and the finite width {gamma} of the resonance (correlation {gamma}E{center_dot}B). The same effect may be produced by the parity-violating energy difference in chiral molecules.
Stefanos D. Anogiannakis; Christos Tzoumanekas; Doros N. Theodorou
2013-01-30
We present atomistic molecular dynamics simulations of two Polyethylene systems where all entanglements are trapped: a perfect network, and a melt with grafted chain ends. We examine microscopically at what level topological constraints can be considered as a collective entanglement effect, as in tube model theories, or as certain pairwise uncrossability interactions, as in slip-link models. A pairwise parameter, which varies between these limiting cases, shows that, for the systems studied, the character of the entanglement environment is more pairwise than collective. We employ a novel methodology, which analyzes entanglement constraints into a complete set of pairwise interactions, similar to slip links. Entanglement confinement is assembled by a plethora of links, with a spectrum of confinement strengths, from strong to weak. The strength of interactions is quantified through a link `persistence', which is the fraction of time for which the links are active. By weighting links according to their strength, we show that confinement is imposed mainly by the strong ones, and that the weak, trapped, uncrossability interactions cannot contribute to the low frequency modulus of an elastomer, or the plateau modulus of a melt. A self-consistent scheme for mapping topological constraints to specific, strong binary links, according to a given entanglement density, is proposed and validated. Our results demonstrate that slip links can be viewed as the strongest pairwise interactions of a collective entanglement environment. The methodology developed provides a basis for bridging the gap between atomistic simulations and mesoscopic slip link models.
Effects of Breakup of Weakly Bound Projectile and Neutron Transfer on Fusion Reactions
Lin, C. J.; Zhang, H. Q.; Yang, F.; Ruan, M.; Liu, Z. H.; Wu, X. K.; Zhou, P.; Zhang, C. L.; Zhang, G. L.; An, G. P.; Jia, H. M.; Xu, X. X. [China Institute of Atomic Energy, P.O. Box 275 (10), Beijing 102413 (China)
2006-11-02
The excitation functions of elastic and quasielastic scattering at backward angles are measured for the systems 16O + 152Sm , 6,7Li + 208Pb. The barrier distributions are extracted from these measured excitation functions and compared with the corresponding fusion barrier distributions. Except some details, the barrier distributions derived from the data of fusion and elastic/quasielastic scattering are almost the same for the tightly bound reaction systems. For the reaction systems with weakly bound projectile, the barrier distributions extracted from quasielastic scattering are obviously different the fusion barrier distributions. However, the barrier distributions extracted from the excitation functions of the quasielastic scattering plus breakup are almost the same as the one extracted from the complete fusion data. This result means that barrier distribution not only bears the information of nuclear structures but also contains the knowledge of reaction mechanisms. In addition, the measured barrier distribution of 32S + 96Zr is flat and extends to lower energy due to the coupling of neutron transfer with positive Q-values, which will result in a significant enhancement effusion cross sections at the subbarrier energies. However, our results show that the complete fusion of the weakly bound projectile with heavy target is suppressed at the above barrier energies as compared with the model predictions.
Stacking weak lensing signals of SZ clusters to constrain cluster physics
Carolyn Sealfon; Licia Verde; Raul Jimenez
2006-01-12
We show how to place constraints on cluster physics by stacking the weak lensing signals from multiple clusters found through the Sunyaev-Zeldovich (SZ) effect. For a survey that covers about 200 sq. deg. both in SZ and weak lensing observations, the slope and amplitude of the mass vs. SZ luminosity relation can be measured with few percent error for clusters at z~0.5. This can be used to constrain cluster physics, such as the nature of feedback. For example, we can distinguish a pre-heated model from a model with a decreased accretion rate at more than 5sigma. The power to discriminate among different non-gravitational processes in the ICM becomes even stronger if we use the central Compton parameter y_0, which could allow one to distinguish between models with pre-heating, SN feedback and AGN feedback, for example, at more than 5sigma. Measurement of these scaling relations as a function of redshift makes it possible to directly observe e.g., the evolution of the hot gas in clusters. With this approach the mass-L_SZ relation can be calibrated and its uncertainties can be quantified, leading to a more robust determination of cosmological parameters from clusters surveys. The mass-L_SZ relation calibrated in this way from a small area of the sky can be used to determine masses of SZ clusters from very large SZ-only surveys and is nicely complementary to other techniques proposed in the literature.
Rej, Pramit; Ghoshal, Arijit
2014-09-15
Formation of Rydberg atoms due to 1s?nlm excitations of hydrogen, for arbitrary n, l, m, by positron impact in weakly coupled plasma has been investigated using a distorted-wave theory in the momentum space. The interactions among the charged particles in the plasma have been represented by Debye-Huckel potentials. Making use of a simple variationally determined wave function for the hydrogen atom, it has been possible to obtain the distorted-wave scattering amplitude in a closed analytical form. A detailed study has been made on the effects of plasma screening on the differential and total cross sections in the energy range 20–300?eV of incident positron. For the unscreened case, our results agree nicely with some of the most accurate results available in the literature. To the best of our knowledge, such a study on the differential and total cross sections for 1s?nlm inelastic positron-hydrogen collisions for arbitrary n, l, m in weakly coupled plasmas is the first reported in the literature.
Searching for the metal-weak thick disc in the solar neighbourhood
Bacham E. Reddy; David L. Lambert
2008-09-05
An abundance analysis is presented of 60 metal-poor stars drawn from catalogues of nearby stars provided by Ariyanto et al. (2005) and Schuster et al. (2006). In an attempt to isolate a sample of metal-weak thick disc stars, we applied the kinematic criteria $V_{\\rm rot} \\geq 100$ km s$^{-1}$, $|U_{LSR}| \\leq 140$ km s$^{-1}$, and $|W_{LSR}| \\leq 100$ km s$^{-1}$. Fourteen stars satisfying these criteria and having [Fe/H] $\\leq -1.0$ are included in the sample of 60 stars. Eight of the 14 have [Fe/H] $\\geq -1.3$ and may be simply thick disc stars of slightly lower than average [Fe/H]. The other six have [Fe/H] from -1.3 to -2.3 and are either metal-weak thick disc stars or halo stars with kinematics mimicking those of the thick disc. The sample of 60 stars is completed by eight thick disc stars, 20 stars of a hybrid nature (halo or thick disc stars), and 18 stars with kinematics distinctive of the halo.
Direct Evidence of the Transition from Weak to Strong MHD Turbulence
Romain Meyrand; Sebastien Galtier; Khurom H. Kiyani
2015-09-21
One of the most important predictions in magnetohydrodynamics (MHD) is that in the presence of a uniform magnetic field $\\textbf{b}_{0}$ a transition from weak to strong wave turbulence should occur when going from large to small perpendicular scales. This transition is believed to be a universal property of several anisotropic turbulent systems. We present for the first time direct evidence of such a transition thanks to a three-dimensional direct numerical simulation of incompressible balanced MHD turbulence with a grid resolution of $3072^2 \\times 256$. From large to small-scales, the change of regime is characterized by i) a change of slope in the energy spectrum going from approximately $-2$ to $-3/2$; ii) an increase of the ratio between the wave and nonlinear times, with a critical ratio of $\\chi_{c}\\sim0.35$; iii) an absence followed by a dramatic increase of the communication between Alfv\\'en modes; and iv) a modification of the iso-contours of energy revealing a transition from a purely perpendicular cascade to a cascade compatible with the critical balance type phenomenology. All these changes happen at approximately the same transition scale and therefore can be seen as manifest signatures of the transition from weak to strong wave turbulence.
The Weak Charge of the Proton: A Search For Physics Beyond the Standard Model
MacEwan, Scott
2015-05-01
The Qweak experiment, which completed running in May of 2012 at Jefferson Laboratory, has measured the parity-violating asymmetry in elastic electron-proton scattering at four-momentum transfer Q^2=0.025 (GeV/c)^2 in order to provide the first direct measurement of the proton?s weak charge, Qpw. The Standard Model makes firm predictions for the weak charge; deviations from the predicted value would provide strong evidence of new physics beyond the Standard Model. Using an 89% polarized electron beam at 145 microA scattering from a 34.4 cm long liquid hydrogen target, scattered electrons were detected using an array of eight fused-silica detectors placed symmetric about the beam axis. The parity-violating asymmetry was then measured by reversing the helicity of the incoming electrons and measuring the normalized difference in rate seen in the detectors. The low Q^2 enables a theoretically clean measurement; the higher order hadronic corrections are constrained using previous parity-violating electron scattering world data. The experimental method will be discussed, with recent results constituting 4% of our total data and projections of our proposed uncertainties on the full data set.
Single-Molecule Dynamics Reveals Cooperative Binding-Folding in Protein Recognition
Wang, Jin; Lu, Qiang N.; Lu, H PETER.
2006-07-01
The study of associations between two biomolecules is the key to understand molecular recognition and function. Molecular function is often thought to be determined by the underlying structures. Here, combining single molecule study of protein binding with an energy landscape inspired microscopic model, we found strong evidences that bio-molecular recognition is determined by flexibilities in addition to structures. Our model is based on coarse grained molecular dynamics performed on the residue level with the energy function biased towards the native binding structure (Go model). With our model, the underlying free energy landscape of the binding can be explored. Two distinct conformational states as free energy minimum, one with partially folding of CBD and significant binding of CBD to CDC42, and another with native folding of CBD and native binding of CBD to CDC42, are clearly seen. This shows the binding process proceeds with significant interface binding of CBD with CDC42 first without complete folding of CBD. Finally binding and folding are coupled with each other cooperatively to reach the native binding state. The single molecule experimental finding of the dynamic fluctuations between the loosely bound and closely bound conformational states can be identified with theoretically calculated free energy minimum and quantitatively explained in our model as a result of binding associated with large conformational changes. Theoretical predictions have identified certain key residues for binding which are consistent with mutational experiments. The combined study provides a test ground for fundamental mechanisms as well as insights into design and further explorations on biomolecular recognition with large conformational changes.
Knott, Michael [Department of Chemistry, Cambridge University, Lensfield Road, Cambridge CB2 1EW (United Kingdom)] [Department of Chemistry, Cambridge University, Lensfield Road, Cambridge CB2 1EW (United Kingdom); Best, Robert B., E-mail: robertbe@helix.nih.gov [Department of Chemistry, Cambridge University, Lensfield Road, Cambridge CB2 1EW (United Kingdom); Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892-0520 (United States)
2014-05-07
Many proteins undergo a conformational transition upon binding to their cognate binding partner, with intrinsically disordered proteins (IDPs) providing an extreme example in which a folding transition occurs. However, it is often not clear whether this occurs via an “induced fit” or “conformational selection” mechanism, or via some intermediate scenario. In the first case, transient encounters with the binding partner favour transitions to the bound structure before the two proteins dissociate, while in the second the bound structure must be selected from a subset of unbound structures which are in the correct state for binding, because transient encounters of the incorrect conformation with the binding partner are most likely to result in dissociation. A particularly interesting situation involves those intrinsically disordered proteins which can bind to different binding partners in different conformations. We have devised a multi-state coarse-grained simulation model which is able to capture the binding of IDPs in alternate conformations, and by applying it to the binding of nuclear coactivator binding domain (NCBD) to either ACTR or IRF-3 we are able to determine the binding mechanism. By all measures, the binding of NCBD to either binding partner appears to occur via an induced fit mechanism. Nonetheless, we also show how a scenario closer to conformational selection could arise by choosing an alternative non-binding structure for NCBD.
USING DNASE DIGESTION DATA TO ACCURATELY IDENTIFY TRANSCRIPTION FACTOR BINDING SITES
Hartemink, Alexander
USING DNASE DIGESTION DATA TO ACCURATELY IDENTIFY TRANSCRIPTION FACTOR BINDING SITES KAIXUAN LUO1. But methods combining DNase digestion data with TF binding specificity information could potentially be used on the genomic digestion prod- ucts of deoxyribonuclease I (DNase I, which we will simply call DNase) might
ContextSensitive Binding by the Laminar Circuits of V1 and V2
Grossberg, Stephen
ContextSensitive Binding by the Laminar Circuits of V1 and V2: Unified Model Perceptual Grouping is presented how laminar circuits visual cortical areas implement contextsensitive binding processes such perceptual grouping and attention. model proposes how specific laminar circuits allow responses visual
Kinetics of Bile Salt Binding to Liposomes Revealed by Carboxyfluorescein Release and
Hinow, Peter
Kinetics of Bile Salt Binding to Liposomes Revealed by Carboxyfluorescein Release and Mathematical by the binding of different bile salts to the leaflets of the lipid bilayer. We find that the permeability of the liposomal bilayer depends on the difference in the concentrations of bile salt in the inner and outer
Contributions to the Binding Free Energy of Ligands to Avidin and Streptavidin
Lazaridis, Themis
of New York, New York, New York ABSTRACT The free energy of binding of a ligand to a macromoleculeContributions to the Binding Free Energy of Ligands to Avidin and Streptavidin Themis Lazaridis is here formally decom- posed into the (effective) energy of interaction, reorganization energy
Using Multiconformation Continuum Electrostatics to Compare Chloride Binding Motifs in -Amylase,
Gunner, Marilyn
Using Multiconformation Continuum Electrostatics to Compare Chloride Binding Motifs in -Amylase electrostatics (MCCE), we show that the changes of chloride binding to -amylase, human serum albumin (HSA) and Omp32 with pH, and of -amylase with mutation agree well with experimental data. The three proteins
Smith, Dayle MA; Straatsma, TP; Squier, Thomas C.
2012-10-03
Calmodulin (CaM) is a highly flexible calcium-binding protein that mediates signal transduction through an ability to differentially bind to highly variable binding sequences in target proteins. To identify how binding affects CaM motions, and its relationship to conformational entropy and target peptide sequence, we have employed fully atomistic, explicit solvent molecular dynamics simulations of unbound CaM and CaM bound to five different target peptides. The calculated CaM conformational binding entropies correlate with experimentally derived conformational entropies with a correlation coefficient R2 of 0.95. Selected side-chain interactions with target peptides restrain interhelical loop motions, acting to tune the conformational entropy of the bound complex via widely distributed CaM motions. In the complex with the most conformational entropy retention (CaM in complex with the neuronal nitric oxide synthase binding sequence), Lys-148 at the C-terminus of CaM forms transient salt bridges alternating between Glu side chains in the N-domain, the central linker, and the binding target. Additional analyses of CaM structures, fluctuations, and CaM-target interactions illuminate the interplay between electrostatic, side chain, and backbone properties in the ability of CaM to recognize and discriminate against targets by tuning its conformational entropy, and suggest a need to consider conformational dynamics in optimizing binding affinities.
Distinct p53 genomic binding patterns in normal and cancer-derived human cells
Botcheva K.; McCorkle S. R.; McCombie W. R.; Dunn J. J.; Anderson C. W.
2011-12-15
We report here genome-wide analysis of the tumor suppressor p53 binding sites in normal human cells. 743 high-confidence ChIP-seq peaks representing putative genomic binding sites were identified in normal IMR90 fibroblasts using a reference chromatin sample. More than 40% were located within 2 kb of a transcription start site (TSS), a distribution similar to that documented for individually studied, functional p53 binding sites and, to date, not observed by previous p53 genome-wide studies. Nearly half of the high-confidence binding sites in the IMR90 cells reside in CpG islands, in marked contrast to sites reported in cancer-derived cells. The distinct genomic features of the IMR90 binding sites do not reflect a distinct preference for specific sequences, since the de novo developed p53 motif based on our study is similar to those reported by genome-wide studies of cancer cells. More likely, the different chromatin landscape in normal, compared with cancer-derived cells, influences p53 binding via modulating availability of the sites. We compared the IMR90 ChIPseq peaks to the recently published IMR90 methylome1 and demonstrated that they are enriched at hypomethylated DNA. Our study represents the first genome-wide, de novo mapping of p53 binding sites in normal human cells and reveals that p53 binding sites reside in distinct genomic landscapes in normal and cancer-derived human cells.
Identification of Substrate Binding Sites in Enzymes by Computational Solvent Mapping
Vajda, Sandor
. Dennis, Biotechnology Research Institute, National Research Council of Canada, Montreal, Canada; L. Brown * 1 Program in Bioinformatics Boston University, Boston, MA 02215, USA 2 Department of Biomedical with the most favorable binding free energy. The method then finds the con- sensus site that binds the highest
A PARLOG Implementation of Government-Binding Theory Robert J. Kuhns
on the principles and constraints of Government- Binding Theory. The parser outputs a set of licensing relations~odules of tile theory. BACKGROUND Parse,'s based oil Government-Binding (GB) Theory have been tile subject\\er, they all approach parsing as a sequential process, and allhough there have been a number o[' efforts oil
STAR/MPI: Binding a Parallel Library to Interactive Symbolic Algebra Systems
Cooperman, Gene
STAR/MPI: Binding a Parallel Library to Interactive Symbolic Algebra Systems Gene Cooperman 1 gene of symbolic algebra systems have felt the need for greater CPU power. Yet few of them have ventured/MPI includes a simple SPMD architecture on top of this MPI binding. An important class of sequential algo
Roberto Chignola; Alessio Del Fabbro; Edoardo Milotti
2009-09-10
We study the dynamics of intracellular calcium oscillations in the presence of proteins that bind calcium on multiple sites and that are generally believed to act as passive calcium buffers in cells. We find that multisite calcium-binding proteins set a sharp threshold for calcium oscillations. Even with high concentrations of calcium-binding proteins, internal noise, which shows up spontaneously in cells in the process of calcium wave formation, can lead to self-oscillations. This produces oscillatory behaviors strikingly similar to those observed in real cells. In addition, for given intracellular concentrations of both calcium and calcium-binding proteins the regularity of these oscillations changes and reaches a maximum as a function noise variance, and the overall system dynamics displays stochastic coherence. We conclude that calcium-binding proteins may have an important and active role in cellular communication.
Marr, Eric; Tardie, Mark; Carty, Maynard; Brown Phillips, Tracy; Wang, Ing-Kae; Soeller, Walt; Qiu, Xiayang Karam, George
2006-11-01
The crystal structure of human adipocyte lipid-binding protein (aP2) with a bound palmitate is reported at 1.5 Å resolution. Human adipocyte lipid-binding protein (aP2) belongs to a family of intracellular lipid-binding proteins involved in the transport and storage of lipids. Here, the crystal structure of human aP2 with a bound palmitate is described at 1.5 Å resolution. Unlike the known crystal structure of murine aP2 in complex with palmitate, this structure shows that the fatty acid is in a folded conformation and that the loop containing Phe57 acts as a lid to regulate ligand binding by excluding solvent exposure to the central binding cavity.
Mask effects on cosmological studies with weak-lensing peak statistics
Liu, Xiangkun; Pan, Chuzhong; Fan, Zuhui; Wang, Qiao
2014-03-20
With numerical simulations, we analyze in detail how the bad data removal, i.e., the mask effect, can influence the peak statistics of the weak-lensing convergence field reconstructed from the shear measurement of background galaxies. It is found that high peak fractions are systematically enhanced because of the presence of masks; the larger the masked area is, the higher the enhancement is. In the case where the total masked area is about 13% of the survey area, the fraction of peaks with signal-to-noise ratio ? ? 3 is ?11% of the total number of peaks, compared with ?7% of the mask-free case in our considered cosmological model. This can have significant effects on cosmological studies with weak-lensing convergence peak statistics, inducing a large bias in the parameter constraints if the effects are not taken into account properly. Even for a survey area of 9 deg{sup 2}, the bias in (? {sub m}, ?{sub 8}) is already intolerably large and close to 3?. It is noted that most of the affected peaks are close to the masked regions. Therefore, excluding peaks in those regions in the peak statistics can reduce the bias effect but at the expense of losing usable survey areas. Further investigations find that the enhancement of the number of high peaks around the masked regions can be largely attributed to the smaller number of galaxies usable in the weak-lensing convergence reconstruction, leading to higher noise than that of the areas away from the masks. We thus develop a model in which we exclude only those very large masks with radius larger than 3' but keep all the other masked regions in peak counting statistics. For the remaining part, we treat the areas close to and away from the masked regions separately with different noise levels. It is shown that this two-noise-level model can account for the mask effect on peak statistics very well, and the bias in cosmological parameters is significantly reduced if this model is applied in the parameter fitting.
Conformational Variability of Organophosphorus Hydrolase upon Soman and Paraoxon Binding
Gomes, Diego Eb; Lins, Roberto D.; Pascutti, Pedro G.; Lei, Chenghong; Soares, Thereza A.
2011-12-31
The bacterial enzyme organophosphorus hydrolase (OPH) exhibits both catalytic and substrate promiscuity. It hydrolyzes bonds in a variety of phosphotriester (P-O), phosphonothioate (P-S), phosphofluoridate (P-F) and phosphonocyanate (F-CN) compounds. However, its catalytic efficiency varies markedly for different substrates, limiting the broad-range application of OPH as catalyst in the bioremediation of pesticides and chemical war agents. In the present study, pK{sub a} calculations and multiple explicit-solvent molecular dynamics (MD) simulations were performed to characterize and contrast the structural dynamics of OPH bound to two substrates hydrolyzed with very distinct catalytic efficiencies: the nerve agent soman (O-pinacolyl-methyl-phosphonofluoridate) and the pesticide paraoxon (diethyl p-nitrophenyl phosphate). pK{sub a} calculations for the substrate-bound and unbound enzyme showed a significant pK{sub a} shift from standard values ({Delta}pK{sub a} = {+-} 3 units) for residues 254His and 275Arg. MD simulations of the doubly protonated 254His revealed a dynamic hydrogen bond network connecting the catalytic residue 301Asp via 254His to 232Asp, 233Asp, 275Arg and 235Asp, and is consistent with a previously postulated proton relay mechanism to ferry protons away from the active site with substrates that do not require activation of the leaving group. Hydrogen bonds between 301Asp and 254His were persistent in the OPH-paraoxon complex but not in the OPH-soman one, suggesting a potential role for such interaction in the more efficient hydrolysis of paraoxon over soman by OPH. These results are in line with previous mutational studies of residue 254His, which led to an increase of the catalytic efficiency of OPH over soman yet decreased its efficiency for paraoxon. In addition, comparative analysis of the molecular trajectories for OPH bound to soman and paraoxon suggests that binding of the latter facilitates the conformational transition of OPH from the open to the closed substate promoting a tighter binding of paraoxon.
Weak Interaction Rates of Nuclei Near the R-Process Paths
Borzov, I. N.; Cuenca-Garcia, J. J.; Langanke, K.; Martinez-Pinedo, G.; Kelic, A. [Gesellschaft fuer Schwerionenforschung, Darmstadt, D-64291 (Germany); Zinner, N. T. [Institute for Physics and Astronomy, University of Aarhus, DK-8000 Aarhus C (Denmark)
2007-05-22
Systematic calculations of the beta- and neutrino-induced rates are performed for the nuclei at Z=92-96 approaching the possible r-process paths in vicinity of the spherical neutron shell at N=184. The nuclear ground states are treated self-consistently in the framework of the local energy-density functional (DF) theory. The beta-strength-functions of the Gamow-Teller and first-forbidden decays are calculated within the continuum QRPA approach of the finite Fermi system theory. The beta-decay half-lives and beta-delayed neutron emission probabilities are analyzed simultaneously. Within the same approach the weak interaction rates are calculated for the fission products around Z{approx_equal}50, N=82 forming the A=130 peak in the r-process isotopic abundance. A shell-model study of selected Pd isotopes is performed. An analysis of available experimental data and theoretical predictions from the FRDM is also presented.
An integral formulation for wave propagation on weakly non-uniform potential flows
Mancini, Simone; Sinayoko, Samuel; Gabard, Gwenael; Tournour, Michel
2015-01-01
An integral formulation for acoustic radiation in moving flows is presented. It is based on a potential formulation for acoustic radiation on weakly non-uniform subsonic mean flows. This work is motivated by the absence of suitable kernels for wave propagation on non-uniform flow. The integral solution is formulated using a Green's function obtained by combining the Taylor and Lorentz transformations. Although most conventional approaches based on either transform solve the Helmholtz problem in a transformed domain, the current Green's function and associated integral equation are derived in the physical space. A dimensional error analysis is developed to identify the limitations of the current formulation. Numerical applications are performed to assess the accuracy of the integral solution. It is tested as a means of extrapolating a numerical solution available on the outer boundary of a domain to the far field, and as a means of solving scattering problems by rigid surfaces in non-uniform flows. The results...
Storage and recall of weak coherent optical pulses with an efficiency of 25%
M. Sabooni; F. Beaudoin; A. Walther; N. Lin; A. Amari; M. Huang; S. Kröll
2009-12-14
We demonstrate experimentally a quantum memory scheme for the storage of weak coherent light pulses in an inhomogeneously broadened optical transition in a Pr^{3+}: YSO crystal at 2.1 K. Precise optical pumping using a frequency stable (about 1kHz linewidth) laser is employed to create a highly controllable Atomic Frequency Comb (AFC) structure. We report single photon storage and retrieval efficiencies of 25%, based on coherent photon echo type re-emission in the forward direction. The coherence property of the quantum memory is proved through interference between a super Gaussian pulse and the emitted echo. Backward retrieval of the photon echo emission has potential for increasing storage and recall efficiency.
Analytical study of the propagation of acoustic waves in a 1D weakly disordered lattice
Richoux, O. Morand, E.; Simon, L.
2009-09-15
This paper presents an analytical approach of the propagation of an acoustic wave through a normally distributed disordered lattice made up of Helmholtz resonators connected to a cylindrical duct. This approach allows to determine analytically the exact transmission coefficient of a weakly disordered lattice. Analytical results are compared to a well-known numerical method based on a matrix product. Furthermore, this approach gives an analytical expression of the localization length apart from the Bragg stopband which depends only on the standard deviation of the normal distribution disorder. This expression permits to study on one hand the localization length as a function of both disorder strength and frequency, and on the other hand, the propagation characteristics on the edges of two sorts of stopbands (Bragg and Helmholtz stopbands). Lastly, the value of the localization length inside the Helmholtz stopband is compared to the localization length in the Bragg stopband.
Anogiannakis, Stefanos D; Theodorou, Doros N
2012-01-01
We present atomistic molecular dynamics simulations of two Polyethylene systems where all entanglements are trapped: a perfect network, and a melt with grafted chain ends. We examine microscopically at what level topological constraints can be considered as a collective entanglement effect, as in tube model theories, or as certain pairwise uncrossability interactions, as in slip-link models. A pairwise parameter, which varies between these limiting cases, shows that, for the systems studied, the character of the entanglement environment is more pairwise than collective. We employ a novel methodology, which analyzes entanglement constraints into a complete set of pairwise interactions, similar to slip links. Entanglement confinement is assembled by a plethora of links, with a spectrum of confinement strengths, from strong to weak. The strength of interactions is quantified through a link `persistence', which is the fraction of time for which the links are active. By weighting links according to their strength,...
Photo-induced strengthening of weak bonding in noble gas dimers
Miyamoto, Yoshiyuki; Miyazaki, Takehide; Rubio, Angel
2014-05-19
We demonstrate through extensive first-principles time-dependent density functional calculations that attractive van der Waals interaction between closed-shell atoms can be enhanced by light with constant spatial intensity. We illustrate this general phenomenon for a He dimer as a prototypical case of complex van der Waals interactions and show that when excited by light with a frequency close to the 1s ? 2p He-atomic transition, an attractive force larger than 7 pN is produced. This force gain is manifested as a larger acceleration of He-He contraction under an optical field. The concerted dynamical motions of the He atoms together with polarity switching of the charge-induced dipole cause the contraction of the dimer. These findings are relevant for the photo-induced control of weakly bonded molecular species, either in gas phase or in solution.
Probing weak force induced parity violation by high resolution mid-infrared molecular spectroscopy
Tokunaga, Sean K; Auguste, Frédéric; Shelkovnikov, Alexander; Daussy, Christophe; Amy-Klein, Anne; Chardonnet, Christian; Darquié, Benoît
2013-01-01
To date no experiment has reached the level of sensitivity required to observe weak nuclear force induced parity violation (PV) energy differences in chiral molecules. In this paper, we present the approach, adopted at Laboratoire de Physique des Lasers (LPL), to measure frequency differences in the vibrational spectrum of enantiomers. We review different spectroscopic methods developed at LPL leading to the highest resolutions, as well as 20 years of CO2 laser stabilization work enabling such precise measurements. After a first attempt to observe PV vibrational frequency shifts using sub-Doppler saturated absorption spectroscopy in a cell, we are currently aiming at an experiment based on Doppler-free two-photon Ramsey interferometry on a supersonic beam. We report on our latest progress towards observing PV with chiral organo-metallic complexes containing a heavy rhenium atom.
Probing weak force induced parity violation by high resolution mid-infrared molecular spectroscopy
Sean K. Tokunaga; Clara Stoeffler; Frédéric Auguste; Alexander Shelkovnikov; Christophe Daussy; Anne Amy-Klein; Christian Chardonnet; Benoît Darquié
2013-09-22
To date no experiment has reached the level of sensitivity required to observe weak nuclear force induced parity violation (PV) energy differences in chiral molecules. In this paper, we present the approach, adopted at Laboratoire de Physique des Lasers (LPL), to measure frequency differences in the vibrational spectrum of enantiomers. We review different spectroscopic methods developed at LPL leading to the highest resolutions, as well as 20 years of CO2 laser stabilization work enabling such precise measurements. After a first attempt to observe PV vibrational frequency shifts using sub-Doppler saturated absorption spectroscopy in a cell, we are currently aiming at an experiment based on Doppler-free two-photon Ramsey interferometry on a supersonic beam. We report on our latest progress towards observing PV with chiral organo-metallic complexes containing a heavy rhenium atom.
Long, Mingsheng; Gong, Youpin; Wei, Xiangfei; Zhu, Chao; Xu, Jianbao; Liu, Ping; Guo, Yufen; Li, Weiwei; Liu, Liwei, E-mail: lwliu2007@sinano.ac.cn [Key Laboratory of Nanodevices and Applications-CAS and Collaborative Innovation Center of Suzhou Nano Science and Technology, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences (CAS), Suzhou 215123 (China); Liu, Guangtong [Institute of Physics, Chinese Academy of Sciences, Beijing 100190 (China)
2014-04-14
We fabricated a vertical structure device, in which graphene is sandwiched between two asymmetric ferromagnetic electrodes. The measurements of electron and spin transport were performed across the combined channels containing the vertical and horizontal components. The presence of electron-electron interaction (EEI) was found not only at low temperatures but also at moderate temperatures up to ?120?K, and EEI dominates over weak localization (WL) with and without applying magnetic fields perpendicular to the sample plane. Moreover, spin valve effect was observed when magnetic filed is swept at the direction parallel to the sample surface. We attribute the EEI and WL surviving at a relatively high temperature to the effective suppress of phonon scattering in the vertical device structure. The findings open a way for studying quantum correlation at relatively high temperature.
Park, Sanghoo; Choe, Wonho, E-mail: wchoe@kaist.ac.kr [Department of Physics, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu, Daejeon 305-701 (Korea, Republic of); Youn Moon, Se [High-enthalpy Plasma Research Center, Chonbuk National University, 567 Baekje-daero, Deokjin-gu, Jeonju 561-756 (Korea, Republic of); Park, Jaeyoung [5771 La Jolla Corona Drive, La Jolla, CA 92037 (United States)
2014-02-24
The electron-atom neutral bremsstrahlung continuum radiation emitted from weakly ionized plasmas is investigated for electron density and temperature diagnostics. The continuum spectrum in 450–1000?nm emitted from the argon atmospheric pressure plasma is found to be in excellent agreement with the neutral bremsstrahlung formula with the electron-atom momentum transfer cross-section given by Popovi?. In 280–450?nm, however, a large discrepancy between the measured and the neutral bremsstrahlung emissivities is observed. We find that without accounting for the radiative H{sub 2} dissociation continuum, the temperature, and density measurements would be largely wrong, so that it should be taken into account for accurate measurement.
In-Medium Chiral Perturbation Theory and Pion Weak Decay in the Presence of Background Matter
Kirchbach, M; Kirchbach, Mariana; Wirzba, Andreas
1997-01-01
Two-point functions related to the pion weak decay constant f_\\pi are calculated from the generating functional of chiral perturbation theory in the mean-field approximation and the heavy-baryon limit. The aim is to demonstrate that Lorentz invariance is violated in the presence of background matter. This fact manifests itself in the splitting of both f_\\pi and the pion mass into uncorrelated time- and spacelike parts. We emphasize the different in-medium renormalizations of the correlation functions, show the inequivalence between the in-medium values of f_\\pi deduced from Walecka-type models, on the one hand, and QCD sum rules, on the other hand, and elaborate on the importance for some nuclear physics observables.
In-Medium Chiral Perturbation Theory and Pion Weak Decay in the Presence of Background Matter
Mariana Kirchbach; Andreas Wirzba
1997-01-07
Two-point functions related to the pion weak decay constant f_\\pi are calculated from the generating functional of chiral perturbation theory in the mean-field approximation and the heavy-baryon limit. The aim is to demonstrate that Lorentz invariance is violated in the presence of background matter. This fact manifests itself in the splitting of both f_\\pi and the pion mass into uncorrelated time- and spacelike parts. We emphasize the different in-medium renormalizations of the correlation functions, show the inequivalence between the in-medium values of f_\\pi deduced from Walecka-type models, on the one hand, and QCD sum rules, on the other hand, and elaborate on the importance for some nuclear physics observables.
Colored-noise magnetization dynamics: from weakly to strongly correlated noise
Tranchida, Julien; Nicolis, Stam
2015-01-01
Statistical averaging theorems allow us to derive a set of equations for the averaged magnetization dynamics in the presence of colored (non-Markovian) noise. The non-Markovian character of the noise is described by a finite auto-correlation time, tau, that can be identified with the finite response time of the thermal bath to the system of interest. Hitherto, this model was only tested for the case of weakly correlated noise (when tau is equivalent or smaller than the integration timestep). In order to probe its validity for a broader range of auto-correlation times, a non-Markovian integration model, based on the stochastic Landau-Lifshitz-Gilbert equation is presented. Comparisons between the two models are discussed, and these provide evidence that both formalisms remain equivalent, even for strongly correlated noise (i.e. tau much larger than the integration timestep).
Colored-noise magnetization dynamics: from weakly to strongly correlated noise
Julien Tranchida; Pascal Thibaudeau; Stam Nicolis
2015-11-06
Statistical averaging theorems allow us to derive a set of equations for the averaged magnetization dynamics in the presence of colored (non-Markovian) noise. The non-Markovian character of the noise is described by a finite auto-correlation time, tau, that can be identified with the finite response time of the thermal bath to the system of interest. Hitherto, this model was only tested for the case of weakly correlated noise (when tau is equivalent or smaller than the integration timestep). In order to probe its validity for a broader range of auto-correlation times, a non-Markovian integration model, based on the stochastic Landau-Lifshitz-Gilbert equation is presented. Comparisons between the two models are discussed, and these provide evidence that both formalisms remain equivalent, even for strongly correlated noise (i.e. tau much larger than the integration timestep).
Correlative methods for dual-species quantum tests of the weak equivalence principle
Barrett, B; Chichet, L; Battelier, B; Gominet, P -A; Bertoldi, A; Bouyer, P; Landragin, A
2015-01-01
Matter-wave interferometers utilizing non-identical elements intrinsically have different sensitivities, and the analysis tools available until now are insufficient for accurately estimating the atomic phase difference under many experimental conditions. In this work, we describe and demonstrate two new methods for extracting the differential phase between dual-species atom interferometers for precise tests of the weak equivalence principle. The first method is a generalized Bayesian analysis, which uses knowledge of the system noise to estimate the differential phase based on a statistical model. The second method utilizes a mechanical accelerometer to reconstruct single-sensor interference fringes based on measurements of the vibration-induced phase. An improved ellipse-fitting algorithm is also implemented as a third method for comparison. These analysis tools are investigated using both numerical simulations and experimental data from simultaneous $^{87}$Rb and $^{39}$K interferometers, and both new techn...
A Hidden Broad-Line Region in the Weak Seyfert 2 Galaxy NGC 788
Laura E. Kay; Edward C. Moran
1998-07-23
We have detected a broad H alpha emission line in the polarized flux spectrum of the Seyfert 2 galaxy NGC 788, indicating that it contains an obscured Seyfert 1 nucleus. While such features have been observed in ~15 other Seyfert 2s, this example is unusual because it has a higher fraction of galaxy starlight in its spectrum, a lower average measured polarization, and a significantly lower radio luminosity than other hidden Seyfert 1s discovered to date. This demonstrates that polarized broad-line regions can be detected in relatively weak classical Seyfert 2s, and illustrates why well-defined, reasonably complete spectropolarimetric surveys at H alpha are necessary in order to assess whether or not all Seyfert 2s are obscured Seyfert 1s.
Weak lensing study of low mass galaxy groups: implications for Omega_m
H. Hoekstra; M. Franx; K. Kuijken; R. G. Carlberg; H. K. C. Yee; H. Lin; S. L. Morris; P. B. Hall; D. R. Patton; M. Sawicki; G. D. Wirth
2000-12-07
We report on the first measurement of the average mass and mass-to-light ratio of galaxy groups by analysing the weak lensing signal induced by these systems. The groups, which have velocity dispersions of 50-400 km/s, have been selected from the Canadian Network for Observational Cosmology Field Galaxy Redshift Survey (CNOC2). This survey allows the identification of a large number of groups with redshifts ranging from z=0.12-0.55, ideal for a weak lensing analysis of their mass distribution. For our analysis we use a sample of 50 groups which are selected on the basis of a careful dynamical analysis of group candidates. We detect a signal at the 99% confidence limit. The best fit singular isothermal sphere model yields an Einstein radius of 0.72+-0.29". This corresponds to a velocity dispersion of 274^{+48}_{-59} km/s (using photometric redshift distributions for the source galaxies), which is in good agreement with the dynamical estimate. Under the assumption that the light traces the mass, we find an average mass-to-light ratio of 191+-83 h Msun/Lsun in the restframe B band. Unlike dynamical estimates, this result is insensitive to problems associated with determining group membership. After correction of the observed mass-to-light ratio for luminosity evolution to z=0, we find 254+-110 h Msun/Lsun, lower than what is found for rich clusters. We use the observed mass-to-light ratio to estimate the matter density of the universe, for which we find Omega_m=0.19+-0.10 (Omega_Lambda=0), in good agreement with other recent estimates. For a closed universe, we obtain Omega_m=0.13+-0.07.
Correlative methods for dual-species quantum tests of the weak equivalence principle
B. Barrett; L. Antoni-Micollier; L. Chichet; B. Battelier; P. -A. Gominet; A. Bertoldi; P. Bouyer; A. Landragin
2015-08-11
Matter-wave interferometers utilizing different isotopes or chemical elements intrinsically have different sensitivities, and the analysis tools available until now are insufficient for accurately estimating the atomic phase difference under many experimental conditions. In this work, we describe and demonstrate two new methods for extracting the differential phase between dual-species atom interferometers for precise tests of the weak equivalence principle. The first method is a generalized Bayesian analysis, which uses knowledge of the system noise to estimate the differential phase based on a statistical model. The second method utilizes a mechanical accelerometer to reconstruct single-sensor interference fringes based on measurements of the vibration-induced phase. An improved ellipse-fitting algorithm is also implemented as a third method for comparison. These analysis tools are investigated using both numerical simulations and experimental data from simultaneous $^{87}$Rb and $^{39}$K interferometers, and both new techniques are shown to produce bias-free estimates of the differential phase. We also report observations of phase correlations between atom interferometers composed of different chemical species. This correlation enables us to reject common-mode vibration noise by a factor of 730, and to make preliminary tests of the weak equivalence principle with a sensitivity of $1.6 \\times 10^{-6}$ per measurement with an interrogation time of $T = 10$ ms. We study the level of vibration rejection by varying the temporal overlap between interferometers in a symmetric timing sequence. Finally, we discuss the limitations of the new analysis methods for future applications of differential atom interferometry.
Subedi, Adesh
2014-12-01
The Qweak experiment has taken data to make a 2.5% measurement of parity violating elastic e+p asymmetry in the four momentum transfer region of 0.0250 (GeV/c)^2. This asymmetry is proportional to the weak charge of the proton, which is related to the weak mixing angle, sin^2(theta_W). The final Qweak measurement will provide the most precise measurement of the weak mixing angle below the Z^0 pole to test the Standard Model prediction. A description of the experimental apparatus is provided in this dissertation. The experiment was carried out using a longitudinally polarized electron beam of up to 180 microampere on a 34.5 cm long unpolarized liquid hydrogen target. The Qweak target is not only the world's highest cryogenic target ever built for a parity experiment but also is the least noisy target. This dissertation provides a detailed description of this target and presents a thorough analysis of the target performance. Statistical analysis of Run 1 data, collected between Feb - May 2011, is done to extract a blinded parity violating asymmetry of size -299.7 ± 13.4 (stat.) ± 17.2 (syst.) ± 68 (blinding) parts-per-billion. This resulted in a preliminary proton's weak charge of value 0.0865 ± 0.0085, a 9% measurement. Based on this blinded asymmetry, the weak mixing angle was determined to be sin^2(theta_W) = 0.23429 ± 0.00211.