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Note: This page contains sample records for the topic "venezuela regulation induced" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


1

Universidad Central de Venezuela Facultad de Ciencias  

E-Print Network [OSTI]

Universidad Central de Venezuela Facultad de Ciencias Escuela de Computación Lecturas en Ciencias, Universidad Central de Venezuela, Ap. 47002, Caracas 1041-A, Venezuela (mmonsalv, Universidad Central de Venezuela, Ap. 47002, Caracas 1041-A, Venezuela (mraydan

Raydan, Marcos

2

Experimental Theatre in Venezuela  

E-Print Network [OSTI]

4 LATIN AMERICAN THEATRE REVIEW Experimental Theatre in Venezuela The I Jornadas de Búsqueda y Experimentación Teatral took place March 21-May 19, 1985 in Caracas. Organized by the Centro Latinoamericano de Creación e Investigación Teatral... of the festival was to give an opportunity for experimental theatre groups to present their work and thus to show the current tendencies of unconventional theatre in Venezuela. The participating groups (among them Shock Teatral, Contradanza, Taller...

Editors

1985-10-01T23:59:59.000Z

3

THE PEARL FISHERY OF VENEZUELA  

E-Print Network [OSTI]

THE PEARL FISHERY OF VENEZUELA Marine Biological Lafi'ir-toiy X.I B K. A. R TT JUN 2 41950 WOODS Albert M. Day, Director Special Scientific Report - Fisheries Ho. 26 THE PEARL FISHERY OF VENEZUELA Paul to Venezuela, made travel arrangements, arranged for the cooperation of Venecuelan agencies, and otheri

4

Cephalopod Resources of Venezuela Introduction  

E-Print Network [OSTI]

Cephalopod Resources of Venezuela Introduction The cephalopods in the Western Central Atlantic producing nations in the Western Central Atlantic are Mexico and Ven ezuela. While Venezuela has the lead in production of octopus (mainly Octopus maya). In Venezuela, both squid and octopus are produced as a by

5

COLOMBIA GUYANA VENEZUELA FR.  

E-Print Network [OSTI]

PERU CHILE ARGENTINA PARAGUAY BOLIVIA COLOMBIA GUYANA SURINAME URUGUAY VENEZUELA FR. GUIANA POPULATION DENSITY, 2000 Population density measures the number of persons per square kilometer of land area the population grids and thus may appear coarse. Lambert Azimuthal Equal Area Projection ´ 0 500 1,000 km

Columbia University

6

¿Qué pasa con el teatro de Venezuela?  

E-Print Network [OSTI]

PASA CON EL TEATRO El\\l VENEZUELA? Lü nueva diaiiiatiirgiaRico contó con Cámara de Venezuela, grupo que presentó diuoallí que, a pesar de que Venezuela sea probablemente el país

Castillo, Susana D.

1973-01-01T23:59:59.000Z

7

Un teatro campesino en Venezuela  

E-Print Network [OSTI]

102 LATIN AMERICAN THEATRE REVIEW Un teatro campesino en Venezuela GUILLERMO KORN Producto espontáneo de la participación colectiva nació el grupo de teatro del Asentamiento Campesino Sabaneta, en el Estado Aragua de Venezuela. Las obras de su..., despertó interés. En la Universidad Central de Venezuela quieren saber más de ustedes. Para eso he venido. . . ? ¿Podrían eventualmente hacer una representación en la Escuela de Comuni cación Social? Almeida: {Claro que sí! Si nos dan un medio para...

Korn, Guillermo

1976-10-01T23:59:59.000Z

8

Hctor L. Palacios Verdes Caracas, Venezuela  

E-Print Network [OSTI]

Héctor L. Palacios Verdes Caracas, Venezuela Phone: ask Email: hectorpal@gmail.com Web page: http://www.ldc.usb.ve/~hlp Citizen: Venezuela Residence: Venezuela Education Ph. D. Informatics and Digital Communication December. Caracas, Venezuela. Thesis: Planning as Branch and Bound: a Constraint Programming implementation. Advisor

Palacios, Héctor

9

The Price of Political Opposition: Evidence from Venezuela's Maisanta  

E-Print Network [OSTI]

Spending in Chavez’s Venezuela”, unpublished manuscript,de la discriminación política en Venezuela. Caracas: Súmate.Producto Interno Bruto de Venezuela, 1957-2001. ” Revista

Hsieh, Chang-Tai; Miguel, Edward; Ortega, Daniel; Rodriguez, Francisco

2009-01-01T23:59:59.000Z

10

Venezuela at a Crossroads: Will the re-election of Chvez be a victory for Venezuela?  

E-Print Network [OSTI]

Venezuela at a Crossroads: Will the re-election of Chávez be a victory for Venezuela? November 2012 as having significantly changed the po- litical landscape and prospects for Venezuela, giving hope to the 44

Habib, Ayman

11

E-Print Network 3.0 - acid regulates ozone-induced Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

ozone-induced Search Powered by Explorit Topic List Advanced Search Sample search results for: acid regulates ozone-induced Page: << < 1 2 3 4 5 > >> 1 Plant Molecular Biology 51:...

12

State and Power after Neoliberalism in Bolivarian Venezuela  

E-Print Network [OSTI]

Gobierno Bolivariano de Venezuela. ———. 2005. Understandingp. 3–15. ———. 2007b. Venezuela: Hugo Chávez and the DeclineA Closed Bridge Mirrors Venezuela’s Many Woes. ” The New

Kingsbury, Donald V.

2012-01-01T23:59:59.000Z

13

UNIVERSIDAD SIMN BOLVAR Caracas-Venezuela  

E-Print Network [OSTI]

UNIVERSIDAD SIM�N BOLÍVAR Caracas-Venezuela INFORME TRIMESTRAL ACERCA DE LA MARCHA DE LA UNIVERSIDAD julio ­ septiembre 2004 Junio, 2005 #12;#12;UNIVERSIDAD SIM�N BOLÍVAR Caracas-Venezuela INFORME

Vásquez, Carlos

14

Universidad Central de Venezuela Facultad de Ciencias  

E-Print Network [OSTI]

Universidad Central de Venezuela Facultad de Ciencias Escuela de Computación Lecturas en Ciencias-02 Centro CCCT Caracas, Abril, 2007. #12;Universidad Central de Venezuela Facultad de Ciencias Escuela de

Raydan, Marcos

15

Universidad Central de Venezuela Facultad de Ciencias  

E-Print Network [OSTI]

Universidad Central de Venezuela Facultad de Ciencias Escuela de Computación Lecturas en Ciencias ecoto@strix.ciens.ucv.ve ecoto@opalo.ciens.ucv.ve Universidad Central de Venezuela. Facultad de Ciencias. Escuela de Computación. Laboratorio de Computación Gráfica (LCG) Venezuela. Caracas Apdo. 47002, 1041-A ND

Coto, Ernesto

16

Universidad Central de Venezuela Facultad de Ciencias  

E-Print Network [OSTI]

Universidad Central de Venezuela Facultad de Ciencias Escuela de Computación Lecturas en Ciencias@lmpa.univ-littoral.fr) Departamento de Computaci´on, Facultad de Ciencias, Universidad Central de Venezuela, Ap. 47002, Caracas 1041-A, Venezuela (mraydan@kuaimare.ciens.ucv.ve). Sponsored by the Center of Scientific Com- puting at UCV. 1 #12

Raydan, Marcos

17

Universidad Central de Venezuela Facultad de Ciencias  

E-Print Network [OSTI]

Universidad Central de Venezuela Facultad de Ciencias Escuela de Computación Una herramienta para. Universidad Central de Venezuela. {ecoto, hnavarro, omaira}@opalo.ciens.ucv.ve **Laboratorio TOOLS. Escuela de Computación. Facultad de Ciencias. Universidad Central de Venezuela. amatteo@isys.ciens.ucv.ve Caracas, Enero

Coto, Ernesto

18

Universidad Central de Venezuela Facultad de Ciencias  

E-Print Network [OSTI]

Universidad Central de Venezuela Facultad de Ciencias Escuela de Computación Lecturas en Ciencias@opalo.ciens.ucv.ve Universidad Central de Venezuela. Facultad de Ciencias. Escuela de Computación. Laboratorio de Computación Gráfica (LCG) Venezuela. Caracas Apdo. 47002, 1041-A. ND 2003-02 Resumen Los grafos son solo abstracciones

Coto, Ernesto

19

Universidad Central de Venezuela Facultad de Ciencias  

E-Print Network [OSTI]

Universidad Central de Venezuela Facultad de Ciencias Escuela de Computación Lecturas en Ciencias) for some E Cn�n with E Venezuela Venezuela, Centro de C´alculo Cient´ifico y Tecnol´ogico, (zenaida.castillo@ciens.ucv.ve). 1 #12;2 R

Astudillo, Reinaldo

20

Universidad Central de Venezuela Facultad de Ciencias  

E-Print Network [OSTI]

Universidad Central de Venezuela Facultad de Ciencias Escuela de Computación Lecturas en Ciencias ecoto@strix.ciens.ucv.ve ecoto@opalo.ciens.ucv.ve Universidad Central de Venezuela. Facultad de Ciencias. Escuela de Computación. Laboratorio de Computación Gráfica (LCG) Venezuela. Caracas Apdo. 47002, 1041-A

Coto, Ernesto

Note: This page contains sample records for the topic "venezuela regulation induced" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


21

Universidad Central de Venezuela Facultad de Ciencias  

E-Print Network [OSTI]

Universidad Central de Venezuela Facultad de Ciencias Escuela de Computación Lecturas en Ciencias Construcción de Algoritmos Ernesto Coto ecoto@strix.ciens.ucv.ve Universidad Central de Venezuela. Facultad de Ciencias. Escuela de Computación. Laboratorio de Computación Gráfica (LCG) Venezuela. Caracas Apdo. 47002

Coto, Ernesto

22

The Importance of Regulation-Induced Innovation for Sustainable Development  

E-Print Network [OSTI]

This article explores the complex relationship between environmental regulation, innovation, and sustainable development within the context of an increasingly globalizing economy. The economic development, environment, and ...

Ashford, Nicholas A.

23

Engineering a Direct and Inducible Protein-RNA Interaction To Regulate RNA Biology  

E-Print Network [OSTI]

The importance and pervasiveness of naturally occurring regulation of RNA function in biology is increasingly being recognized. A common mechanism uses inducible protein?RNA interactions to shape diverse aspects of cellular ...

Belmont, Brian Joshua

24

Plenia Locatel Group: Globalizing from Venezuela  

E-Print Network [OSTI]

In 2009 the founders and top executives of Plenia Locatel Group, a retail business in Venezuela specializing in health care products and services, were planning a global

Gibson, Cyrus

2009-05-01T23:59:59.000Z

25

Original article Regulation of inducible nitric oxide synthase  

E-Print Network [OSTI]

of the MCF- 7 human breast cancer cell line. The results showed that biochanin A treatment induced dose- and time- dependent inhibition on MCF-7 cell growth at concentrations above 20 µg.mL­1. An examination of treated MCF-7 cell morphology revealed condensation of the chromosome and dehydration of the cyto- plasm

Paris-Sud XI, Université de

26

TIMP3 is the primary TIMP to regulate agonist-induced vascular remodelling and hypertension  

E-Print Network [OSTI]

3 is the primary TIMP to regulate agonist- induced vascular remodelling and hypertension Ratnadeep Hypertension is accompanied by structural remodelling of vascular extracellular matrix (ECM). Tissue inhibitor. In response to a hypertensive stimulus, the balance between MMPs and TIMPs is altered. We examined the role

MacMillan, Andrew

27

A soil bacterium regulates plant acquisition of iron via deficiency-inducible mechanisms  

E-Print Network [OSTI]

A soil bacterium regulates plant acquisition of iron via deficiency-inducible mechanisms Huiming in most soils. While certain soil microbes produce chelating agents that enhance the solubility of iron understanding that select soil microbes play a signaling role in activating growth and stress responses

Paré, Paul W.

28

La República y las Letras — literatura y carácter nacional en Brasil y Venezuela  

E-Print Network [OSTI]

nacional en Brasil y Venezuela* Introducción La Segundaes la nación (Brasil y Venezuela), pero este adentro sePor lo en esta nueva Venezuela es fundamental. Ésta será

Oliveira, Emanuelle K. F.

1995-01-01T23:59:59.000Z

29

Reflections on relationships between national and world events and development of dermatology. Venezuela as a model  

E-Print Network [OSTI]

development of dermatology. Venezuela as a model MauricioVargas School of Medicine, Central University of Venezuela,Caracas Venezuela. ABSTRACT From a personal vantage, the

Goihman-Yahr, Mauricio

2013-01-01T23:59:59.000Z

30

Hacia una redefinición del desarraigo: diálogos narrativos entre Mozambique y Venezuela  

E-Print Network [OSTI]

Banco Central de Venezuela. “Indicadores”. Internet. 20entre Mozambique y Venezuela MAGDALENA LÓPEZ UNIVERSIDADE DEen pedazos” (86). Venezuela, como la aldea de Tizangara,

López, Magdalena

2014-01-01T23:59:59.000Z

31

Equal rights for equal action : women's mobilization for suffrage in Venezuela  

E-Print Network [OSTI]

and Dictatorship in Venezuela, 1945-1959. Hamden, CT: Archonand Political Change in Venezuela. Princeton, NJ: Princetonand the Church in Venezuela. ” Journal of Interamerican

Skog, Erica Lynn

2008-01-01T23:59:59.000Z

32

The Ambiguous Transition: Building State Capacity and Expanding Popular Participation in Venezuela's Agrarian Reform  

E-Print Network [OSTI]

El Universal, Caracas, Venezuela. Bengelsdorf, Carollee.Crisis and Reform in Venezuela. ” Journal of Interamerican2):27-61. Datamonitor. (2004). “Venezuela Country Profile. ”

Page, Tiffany Linton

2011-01-01T23:59:59.000Z

33

Massive Variability Surveys from Venezuela  

E-Print Network [OSTI]

At the Venezuela National Astronomical Observatory we are carrying out variability surveys spanning many hundreds of square degrees near the celestial equator, using an 8k x 8k CCD Mosaic Camera optimized for drift-scanning on a 1m Schmidt telescope. Among the initial efforts was a project to obtain the first moderately deep, homogeneous sample of young stars over an area of ~180sqr.deg. encompassing the entire Orion OB1 association, one of the nearest and most active regions of star formation. The results show that variability is a powerful technique to identify pre-main sequence populations, specially in sparse areas devoid of gas and dust. We are currently developing a massive database, equipped with web-based data mining tools, that will make our data and results available to the astronomical community.

Cesar Briceno

2003-04-03T23:59:59.000Z

34

Venezuela : dix ans de gouvernement Chvez Julien Rebotier1  

E-Print Network [OSTI]

1 Venezuela : dix ans de gouvernement Chávez Julien Rebotier1 , Sandrine Revet2 Au Venezuela, le mesures phares pour le proceso, du nom donné au « processus révolutionnaire » en cours au Venezuela. L du Parti socialiste unifié du Venezuela (PSUV). Les élections régionales du 23 novembre 2008 ont, en

Paris-Sud XI, Université de

35

Four New Hypancistrus (Siluriformes: Loricariidae) from Amazonas, Venezuela  

E-Print Network [OSTI]

Four New Hypancistrus (Siluriformes: Loricariidae) from Amazonas, Venezuela JONATHAN W. ARMBRUSTER. lunaorum are described based on specimens from the upper Ri´o Orinoco of southern Venezuela. Hypancistrus la base de especi´menes provenientes de la cuenca alta del ri´o Orinoco en el sur de Venezuela

Armbruster, Jonathan W.

36

BROWN Y FERNNDEZ, Heliconiini de Venezuela Los Heliconiini (Lepidoptera, Nymphalidae)  

E-Print Network [OSTI]

BROWN Y FERNÁNDEZ, Heliconiini de Venezuela 29 Los Heliconiini (Lepidoptera, Nymphalidae) de Venezuela KEITH S. BROWN, JR.* Y F. FERNÁNDEZ Y�PEZ** RESUMEN Se ilustran y presentan datos sobre variación, distribución y biología de las 42 especies y 88 subespecies de Heliconiini conocidas de Venezuela, con

Mallet, James

37

Repblica Bolivariana de Venezuela Consejo Nacional de Universidades  

E-Print Network [OSTI]

1 República Bolivariana de Venezuela Consejo Nacional de Universidades Núcleo de Vice requerida para una función determinada. #12;2 República Bolivariana de Venezuela Consejo Nacional de mundo tecnologizado y globalizado que habitamos. " #12;3 República Bolivariana de Venezuela Consejo

Vásquez, Carlos

38

Sir --Venezuela has entered 2003 deadlocked in a dangerous political  

E-Print Network [OSTI]

Sir -- Venezuela has entered 2003 deadlocked in a dangerous political confrontation and a general to preserve Venezuela's science and its natural environment, which is rich in biodiversity. We ask for Scientific Research, PO Box 21827, Caracas 1020A, Venezuela correspondence NATURE |VOL 421 |30 JANUARY 2003

Chapman, Clark R.

39

Original article Honey production in Venezuela: effects of feeding  

E-Print Network [OSTI]

Original article Honey production in Venezuela: effects of feeding sugar syrup on colony weight to the nectar flow was studied through a complete honey production sea- son in Venezuela. A significant honeybee / European honeybee / feeding / honey production / Venezuela INTRODUCTION Feeding honey bee

Paris-Sud XI, Université de

40

Light-induced nuclear import of phytochrome-A:GFP fusion proteins is differentially regulated in transgenic tobacco  

E-Print Network [OSTI]

Light-induced nuclear import of phytochrome-A:GFP fusion proteins is differentially regulated of the fusion protein was observed. By contrast, light-dependent nuclear import of the same fusion protein have recently shown that nuclear import of rice phyA:GFP is regulated by VLFR in transgenic tobacco

Schäfer, Eberhard

Note: This page contains sample records for the topic "venezuela regulation induced" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


41

Organo de VENEZUELA ESPERANTO-ASOCIO 33-a Jaro = N. 77 = 2-a Semestro 2005  

E-Print Network [OSTI]

VENEZUELA STELO Organo de VENEZUELA ESPERANTO-ASOCIO 33-a Jaro = N. 77 = 2-a Semestro 2005 ISSN venezuela kulturo, historio kaj idiosinkrazio (Venezuela Esperanto-Asocio, Caracas, 1975); b) La traduko de L A Apartado 47675, Caracas 1041 ­ A http://www.esperanto-ve.org esperanto-en-venezuela

Sirvent, Víctor F.

42

Study Abroad in Venezuela ON-SITE GUIDE 201415  

E-Print Network [OSTI]

Study Abroad in Venezuela ON-SITE GUIDE 2014­15 S T U D Y A B R O A D THE AMERICAS #12;2 Important and can contact the on-site director if needed. In Venezuela VENUSA College 49-49 Avenida Urdaneta Edificio Guilam Mérida, Venezuela Phone: 58.274.263.7631 Fax: 58.274.263.3525 www

Weiblen, George D

43

Le Venezuela en un clin d'oeil !  

E-Print Network [OSTI]

Le Venezuela en un clin d'oeil ! Vie scolaire CALENDRIER UNIVERSITAIRE Peut varier d votre session à l'Université de Montréal. SYST�ME D'ENSEIGNEMENT Québec Venezuela Baccalauréat. Le Venezuela étant un pays limitrophe à la Colombie, le thème de la sécurité est un sujet important à

Charette, André

44

REPBLICA BOLIVARIANA DE VENEZUELA Consejo Nacional de Universidades  

E-Print Network [OSTI]

REP�BLICA BOLIVARIANA DE VENEZUELA Consejo Nacional de Universidades Núcleo de Autoridades de Instituciones de Educación Universitaria de Venezuela (NAEX), reunido en sesión Ordinaria en la sede de la Dirección de Extensión de la Universidad Central de Venezuela en la ciudad de Caracas el día 15 de mayo de

Vásquez, Carlos

45

Study Abroad in Venezuela ON-SITE GUIDE 201415  

E-Print Network [OSTI]

Study Abroad in Venezuela ON-SITE GUIDE 2014­15 S T U D Y A B R O A D THE AMERICAS #12;2 Important and can contact the on-site director if needed. In Venezuela VENUSA College 49-49 Avenida Urdaneta Edificio Guilam Mérida, Venezuela Phone: 58.274.263.7631 Fax: 58.274.263.3525 www.VENUSAcollege.org Francy

Minnesota, University of

46

alto orinoco venezuela: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Venezuela, aerial view looking north. important area of natural hazard research Eaton, L. Scott 118 Different methodologies for obtaining a permeability distribution in...

47

E-Print Network 3.0 - astrobiology caracas venezuela Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

caracas venezuela Search Powered by Explorit Topic List Advanced Search Sample search results for: astrobiology caracas venezuela Page: << < 1 2 3 4 5 > >> 1 Geophysical Research...

48

Prostaglandin E2 Receptor, EP3, Is Induced in Diabetic Islets and Negatively Regulates Glucose-and Hormone-  

E-Print Network [OSTI]

Prostaglandin E2 Receptor, EP3, Is Induced in Diabetic Islets and Negatively Regulates Glucose, the gene for the pros- taglandin E receptor 3 (EP3), was upregulated with diabetes. The EP3 receptor involved in the synthesis of PGE2. We hypothesized that increased signaling through EP3 might be coincident

Attie, Alan D.

49

e-Science perspectives in Venezuela  

E-Print Network [OSTI]

We describe the e-Science strategy in Venezuela, in particular initiatives by the Centro Nacional de Calculo Cientifico Universidad de Los Andes (CECALCULA), Merida, the Universidad de Los Andes (ULA), Merida, and the Instituto Venezolano de Investigaciones Cientificas (IVIC), Caracas. We present the plans for the Venezuelan Academic Grid and the current status of Grid ULA supported by Internet2. We show different web-based scientific applications that are being developed in quantum chemistry, atomic physics, structural damage analysis, biomedicine and bioclimate within the framework of the E-Infrastructure shared between Europe and Latin America (EELA)

Díaz, G; Hamar, V; Hoeger, H; Mendoza, C; Mendez, Z; Núñez, L A; Ruiz, N; Torrens, R; Uzcategui, M

2008-01-01T23:59:59.000Z

50

Martinez, Carlos, Michael Fox and JoJo Farrell. Venezuela Speaks! Voices from the Grassroots. Oakland, CA: PM Press, 2010. 343 pp.  

E-Print Network [OSTI]

well read specialists on Venezuela. This book represents anthe grassroots movements in Venezuela today. Michelle LeighFOX and JOJO FARRELL. Venezuela Speaks! Voices from the

Farrell, Michelle Leigh

2010-01-01T23:59:59.000Z

51

Late Quaternary climate change from delta 13 O records of multiple species of planktonic foraminifera: High-resolution records from the Anoxic Cariaco Basin, Venezuela  

E-Print Network [OSTI]

the Lake Valencia Basin, Venezuela, Ecology, 66, 1279-1295,1954. waters of eastern Venezuela, Bol. Inst. Oceanogr.Los foraminiferos de Venezuela (resumen), Acta Geol. Hisp. ,

Lin, Hui-Ling; Peterson, Larry C; Overpeck, Jonathan T; Trumbore, Susan E; Murray, David W

1997-01-01T23:59:59.000Z

52

e-Science initiatives in Venezuela  

E-Print Network [OSTI]

Within the context of the nascent e-Science infrastructure in Venezuela, we describe several web-based scientific applications developed at the Centro Nacional de Calculo Cientifico Universidad de Los Andes (CeCalCULA), Merida, and at the Instituto Venezolano de Investigaciones Cientificas (IVIC), Caracas. The different strategies that have been followed for implementing quantum chemistry and atomic physics applications are presented. We also briefly discuss a damage portal based on dynamic, nonlinear, finite elements of lumped damage mechanics and a biomedical portal developed within the framework of the \\textit{E-Infrastructure shared between Europe and Latin America} (EELA) initiative for searching common sequences and inferring their functions in parasitic diseases such as leishmaniasis, chagas and malaria.

Chaves, J L; Hamar, V; Isea, R; Rojas, F; Ruiz, N; Torrens, R; Uzcategui, M; Florez-Lopez, J; Hoeger, H; Mendoza, C; Núñez, L A

2007-01-01T23:59:59.000Z

53

A reservoir management strategy for multilayered reservoirs in eastern Venezuela  

E-Print Network [OSTI]

A reservoir management strategy has been developed for a field located in eastern Venezuela. The field contains deep, high pressure, multilayer reservoirs. A thorough formation evaluation was accomplished using the log data, core data, PVT data...

Espinel Diaz, Arnaldo Leopoldo

1998-01-01T23:59:59.000Z

54

Tax effects upon oil field development in Venezuela  

E-Print Network [OSTI]

Important reforms have been made to the oil sector tax code in Venezuela. Given its diversity of oil resources, there was a concern that some resources were not being exploited because of the structure of the tax code. ...

Manzano, Osmel

2000-01-01T23:59:59.000Z

55

The Difference Between Certainly and Perhaps: The Bargaining Strategies of Venezuela and Argentina In Commercial Debt Negotiations  

E-Print Network [OSTI]

n.a. n.a. Brazil Mexico Venezuela Chile Total Note: BankThe Renegotiation of Venezuela's Foreign Debt During 1982of repayment was whether Venezuela would have to accept an

Doherty, E.

1995-01-01T23:59:59.000Z

56

Edinburgh Research Explorer Flavones induce neutrophil apoptosis by down-regulation of Mcl-  

E-Print Network [OSTI]

- regulation of Mcl-1 via a proteasomal- dependent pathway Christopher D. Lucas,*,1 Keith C. Allen,* David A. Dorward,* Laura J. Hoodless,* Lauren A. Melrose,* John A. Marwick,* Carl S. Tucker, Christopher Haslett

Millar, Andrew J.

57

In situ combustion field experiences in Venezuela  

SciTech Connect (OSTI)

A literature review of four in situ combustion projects: in Miga, Tia Juana, Melones and Morichal fields in Venezuela was made, and a summary of these projects is presented. Reservoir description and project performance data were analyzed. The behavior of the four in situ combustion field tests can be summarized as follows: The problems most often encountered were corrosion and high temperature producing wells. The direction in which the burning front moved was guided essentially by reservoir characteristics. The produced oil was upgraded by about 4{degrees} API, and viscosity was substantially reduced. For Mirochal and Miga fields, the analyses of available information from the combustion projects indicated that the process has been successful in the affected region. Conclusions from this review indicate that the two most frequent problems encountered were operational problems in producing wells and the direction of the burning front. The heterogeneous nature of the sands probably resulted in the burning front moving in a preferential direction, hence reducing areal sweep efficiency.

Villalba, M.; Estrada, M.; Bolivar, J. [INTEVEP, Caracas (Venezuela)

1995-02-01T23:59:59.000Z

58

Ecology of large piscivorous fishes in Guri Reservoir, Venezuela, with notes on fish community structure  

E-Print Network [OSTI]

Venezuela's growing human population is accompanied by a growing need for electricity which has largely been met with hydroelectric power, and yet the full effects of river impoundment on river ecosystems are not known. Venezuela currently has...

Williams, John David

1995-01-01T23:59:59.000Z

59

La República y las Letras — literatura y carácter nacional en Brasil y Venezuela  

E-Print Network [OSTI]

o mito da revolução no Brasil (1897- francesa e a formaçãoy carácter nacional en Brasil y Venezuela* Introducción LaEl adentro es la nación (Brasil y Venezuela), pero este

Oliveira, Emanuelle K. F.

1995-01-01T23:59:59.000Z

60

Accelerated Publications Three-Dimensional Structure of DesVI from Streptomyces Venezuelae: A Sugar  

E-Print Network [OSTI]

Accelerated Publications Three-Dimensional Structure of DesVI from Streptomyces Venezuelae: A Sugar for the biosynthesis of dTDP-desosamine in Streptomyces Venezuelae, with the last step catalyzed by DesVI, an N

Holden, Hazel

Note: This page contains sample records for the topic "venezuela regulation induced" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


61

Molecular architecture of DesV from Streptomyces venezuelae: A PLP-dependent transaminase involved in  

E-Print Network [OSTI]

Molecular architecture of DesV from Streptomyces venezuelae: A PLP-dependent transaminase involved are required for its biosynthesis in Streptomyces venezuelae. The focus of this article is DesV, which

Holden, Hazel

62

From Saudi Arabia to Venezuela: Energy Resources, Market Factors & ConflictsEnergy Resources, Market Factors & Conflicts  

E-Print Network [OSTI]

From Saudi Arabia to Venezuela: Energy Resources, Market Factors & ConflictsEnergy Resources, or in U.S. relations with Venezuela, Russia, China, Saudi Arabia, Israel and Nigeria? We will analyze

O'Donnell, Tom

63

Pathogenicity of seven species of the Botryosphaeriaceae on Eucalyptus clones in Venezuela  

E-Print Network [OSTI]

Pathogenicity of seven species of the Botryosphaeriaceae on Eucalyptus clones in Venezuela S. R Milla, 5101-A Mérida, Venezuela. B Department of Genetics, Forestry and Agricultural Biotechnology found on Eucalyptus spp. in Venezuela. An initial inoculation trial was conducted using seven species

64

MARINE PALEOENVIRONMENTS OF MIOCENEPLIOCENE FORMATIONS OF NORTH-CENTRAL FALCO N STATE, VENEZUELA  

E-Print Network [OSTI]

MARINE PALEOENVIRONMENTS OF MIOCENE­PLIOCENE FORMATIONS OF NORTH-CENTRAL FALCO´ N STATE, VENEZUELA Venezuela, were used in determinations of the marine paleoenvironments of the Urumaco, Codore, Caujarao, La sequences of Falco´n are compared to other formations of Venezuela and Colombia with similar

Bermingham, Eldredge

65

Potential role of event-driven sediment transport on sediment accumulation in the Cariaco Basin, Venezuela  

E-Print Network [OSTI]

Basin, Venezuela Laura Lorenzoni a, , Claudia R. Benitez-Nelson b,c , Robert C. Thunell b,c , David, Venezuela e Venezuelan Foundation for Seismological Research (FUNVISIS), Apartado Postal 76880, Caracas 1070-A, Venezuela a b s t r a c ta r t i c l e i n f o Article history: Received 8 June 2011 Received

Meyers, Steven D.

66

Receiver function study of the crustal structure of the southeastern Caribbean plate boundary and Venezuela  

E-Print Network [OSTI]

and Venezuela Fenglin Niu,1 Tammy Bravo,2 Gary Pavlis,2 Frank Vernon,3 Herbert Rendon,4 Maximiliano Bezada,1 broadband array deployed under the BOLIVAR project and the permanent national seismic network of Venezuela northeastern Venezuela and the Venezuelan Andes. There is a good correlation between crustal structure

Niu, Fenglin

67

BREEDING BIOLOGY AND NATURAL HISTORY OF THE SLATE-THROATED WHITESTART IN VENEZUELA  

E-Print Network [OSTI]

BREEDING BIOLOGY AND NATURAL HISTORY OF THE SLATE-THROATED WHITESTART IN VENEZUELA ROMA´ N A´ National Park, Venezuela. Nesting activity peaked in late April and May. Only the female built the nest is the most common race in the Andes of Venezuela, Colombia, and part of Ecuador. Genetic information for our

Martin, Thomas E.

68

Evidence for clonal propagation in natural isolates of Plasmodium falciparum from Venezuela  

E-Print Network [OSTI]

Evidence for clonal propagation in natural isolates of Plasmodium falciparum from Venezuela Ludmel, Estado Aragua, Venezuela; Division of Parasitic Diseases, National Center for Infectious Diseases, 2001 We have analyzed 75 isolates of Plasmodium falciparum, collected in Venezuela during both the dry

69

Quantifying the seasonal variations in fluvial and eolian sources of terrigenous material to Cariaco Basin, Venezuela  

E-Print Network [OSTI]

to Cariaco Basin, Venezuela Aurora C. Elmore a,*, Robert C. Thunell b , Richard Styles b , David Black c, Venezuela a r t i c l e i n f o Article history: Received 27 February 2008 Accepted 10 November 2008 the northern continental shelf of Venezuela and consists of two 1400 m deep sub-basins separated by an 900 m

Meyers, Steven D.

70

POTENTIAL EFFECTS OF GLOBAL CLIMATIC CHANGE ON THE PHENOLOGY AND YIELD OF MAIZE IN VENEZUELA *  

E-Print Network [OSTI]

POTENTIAL EFFECTS OF GLOBAL CLIMATIC CHANGE ON THE PHENOLOGY AND YIELD OF MAIZE IN VENEZUELA de Ciencias, Universidad de Los Andes, Mdrida 5101, Venezuela 21nstitute of Applied Sciences, Venezuela 4Centro de Estudios Avanzados del Clima Tropical (CEACT), Ministerio deI Ambiente y de los

Robock, Alan

71

BREEDING BIOLOGY OF THE GOLDEN-FACED TYRANNULET (ZIMMERIUS CHRYSOPS) IN VENEZUELA  

E-Print Network [OSTI]

BREEDING BIOLOGY OF THE GOLDEN-FACED TYRANNULET (ZIMMERIUS CHRYSOPS) IN VENEZUELA WILLIAM GOULDING1 Park, Venezuela during the 2002 to 2008 breeding seasons. The enclosed nest was similar to descriptions, it is broadly distributed with a range that extends from Peru, north through the Andes to Colombia and Venezuela

Martin, Thomas E.

72

Ingeniero Diana Awais GACETA OFICIAL DE LA REPBLICA BOLIVARIANA DE VENEZUELA  

E-Print Network [OSTI]

Ingeniero Diana Awais GACETA OFICIAL DE LA REP�BLICA BOLIVARIANA DE VENEZUELA A�O CXXX-MES IX Funcional, que en ella se especifican. REP�BLICA BOLIVARIANA DE VENEZUELA CONSEJO NACIONAL DE UNIVERSIDADES de la República Bolivariana de Venezuela, introduce innovaciones en el campo jurídico

Vásquez, Carlos

73

TWO NEW SPECIES OF LEPIDOCYRTUS FROM PARAMO DE MUCUBAJI MERIDA, VENEZUELA  

E-Print Network [OSTI]

TWO NEW SPECIES OF LEPIDOCYRTUS FROM PARAMO DE MUCUBAJI MERIDA, VENEZUELA (COLLEMBOLA ejemplares colectados en Paramo de Mucubaji, Estado de Merida, Venezuela. Los individuos fueron encontrados in Venezuela but only one, L. summersii (MacGillivray) 1894, has been described or reported from this country

Mari-Mutt, José A.

74

Nitrogen isotope dynamics of the Cariaco Basin, Venezuela Robert C. Thunell,1  

E-Print Network [OSTI]

Nitrogen isotope dynamics of the Cariaco Basin, Venezuela Robert C. Thunell,1 Daniel M. Sigman,2 of Venezuela. Water column denitrification occurring in the basin has only a very small isotopic imprint-Karger, Y. Astor, and R. Varela (2004), Nitrogen isotope dynamics of the Cariaco Basin, Venezuela, Global

Sigman, Daniel M.

75

NATURAL HAZARDS ON ALLUVIAL FANS: THE VENEZUELA DEBRIS FLOW AND FLASH FLOOD DISASTER  

E-Print Network [OSTI]

NATURAL HAZARDS ON ALLUVIAL FANS: THE VENEZUELA DEBRIS FLOW AND FLASH FLOOD DISASTER In December Venezuela. Rainfall on December 2-3 totaled 200 millimeters (8 inches) and was followed by a major storm, Denver, Colorado, Naples, Italy, and Vargas, Venezuela. In time scales spanning thousands of years

Eaton, L. Scott

76

Ecology of an isolated mangrove lagoon (Playa Medina, Venezuela) and its potential  

E-Print Network [OSTI]

Ecology of an isolated mangrove lagoon (Playa Medina, Venezuela) and its potential use as sewage pond Teresa Vegas Vilarrubia Geohidra Consultores C.A.. P.O. Box 47851, Caracas 1040-A, Venezuela conditions of a coastal mangrove lagoon in Venezuela which is completely isolated from the sea, lacking any

Vegas Vlarrúbia, Teresa

77

EPIDEMIOLOGY OF BOVINE LEUKEMIA IN VENEZUELA C. MARN NANCY M. DE LPEZ LUISA ALVAREZ O. LOZANO  

E-Print Network [OSTI]

EPIDEMIOLOGY OF BOVINE LEUKEMIA IN VENEZUELA C. MARÍN NANCY M. DE L�PEZ LUISA ALVAREZ O. LOZANO W. ESPANA H. CASTA�OS A. LE�N '! Instltuto de Investigaciones Veterinarias, Apartado 70. Maracay. Venezuela. R6sum6 EPIDEMIOLOGIE DE LA LEUCOSE BOVINE AU VENEZUELA. - Environ 20 000 bovins de races autochtones

Paris-Sud XI, Université de

78

Mantle flow beneath northwestern Venezuela: Seismic evidence for a deep origin of the Mrida Andes  

E-Print Network [OSTI]

Mantle flow beneath northwestern Venezuela: Seismic evidence for a deep origin of the Mérida Andes University, Houston, TX, USA b Fundación de Investigaciones Simológicas (FUNVISIS), Caracas, Venezuela a b wave splitting from SKS data recorded by the national seismic network of Venezuela and a linear

Niu, Fenglin

79

Be dating of river terraces of Santo Domingo river, on Southeastern flank of the Mrida Andes, Venezuela: Tectonic and climatic  

E-Print Network [OSTI]

, Venezuela: Tectonic and climatic implications Oswaldo Guzmán a, b, *, Riccardo Vassallo b , Franck Audemard, Caracas 1081-A, Venezuela b ISTerre, Université de Savoie, CNRS, F-73376 Le Bourget du Lac, France c, Venezuela d Escuela de Geología, Minas y Geofísica, Facultad de Ingeniería, Universidad Central de Venezuela

80

Molecular dynamics simulation of phosphorylation-induced conformational transitions in the mycobacterium tuberculosis response regulator PrrA  

SciTech Connect (OSTI)

Phosphorylation-activated modulation of response regulators (RR) is predominantly used by bacteria as a strategy in regulating their two-component signaling (TCS) systems, the underlying molecular mechanisms are however far from fully understood. In this work we have conducted a molecular dynamics (MD) simulation of the phosphorylation-induced conformational transitions of RRs with the Mycobacterium Tuberculosis PrrA as a particular example. Starting from the full-length inactive structure of PrrA we introduced a local disturbance by phosphorylating the conserved aspartic acid residue, Asp-58, in the regulatory domain. A Go-model-type algorithm packaged with AMBER force fields was then applied to simulate the dynamics upon phosphorylation. The MD simulation shows that the phosphorylation of Asp-58 facilitates PrrA, whose inactive state has a compact conformation with a closed interdomain interface, to open up with its interdomain separation being increased by an average of about 1.5 {angstrom} for a simulation of 20 ns. The trans-activation loop, which is completely buried within the interdomain interface in the inactive PrrA, is found to become more exposed with the phosphorylated structure as well. These results provide more structural details of how the phosphorylation of a local aspartate activates PrrA to undergo a global conformational rearrangement toward its extended active state. This work also indicates that MD simulations can serve as a fast tool to unravel the regulation mechanisms of all RRs, which is especially valuable when the structures of full-length active RRs are currently unavailable.

Chen, Guo [Los Alamos National Laboratory; Mcmahon, Benjamin H [Los Alamos National Laboratory; Tung, Chang - Shung [Los Alamos National Laboratory

2008-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "venezuela regulation induced" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


81

An investigation of rainfall variability and distribution in Venezuela  

E-Print Network [OSTI]

'966. Grosske, F. , Sabre I a Pluviosidad en Caracas, Universidad Central De Venezuela, Facultad De Ingenieria, Depart- amento De Meteorogia e Hidrologia, 144 pp. , Marzo 1967. Henry, tI. K. , Gr if'ithes, 3- F . , Cobb, G. L. and Coligado, M. C. , "Research...

Gibson, Donald Reid

1968-01-01T23:59:59.000Z

82

Magnetically-Regulated Fragmentation Induced by Nonlinear Flows and Ambipolar Diffusion  

E-Print Network [OSTI]

We present a parameter study of simulations of fragmentation regulated by gravity, magnetic fields, ambipolar diffusion, and nonlinear flows. The thin-sheet approximation is employed with periodic lateral boundary conditions, and the nonlinear flow field ("turbulence") is allowed to freely decay. In agreement with previous results in the literature, our results show that the onset of runaway collapse (formation of the first star) in subcritical clouds is significantly accelerated by nonlinear flows in which a large-scale wave mode dominates the power spectrum. In addition, we find that a power spectrum with equal energy on all scales also accelerates collapse, but by a lesser amount. For a highly super-Alfvenic initial velocity field with most power on the largest scales, the collapse occurs promptly during the initial compression wave. However, for trans-Alfvenic perturbations, a subcritical magnetic field causes a rebound from the initial compression, and the system undergoes several oscillations before runaway collapse occurs. Models that undergo prompt collapse have highly supersonic infall motions at the core boundaries. Cores in magnetically subcritical models with trans-Alfvenic initial perturbations also pick up significant systematic speeds by inheriting motions associated with magnetically-driven oscillations. Core mass distributions are much broader than in models with small-amplitude initial perturbations, although the disturbed structure of cores that form due to nonlinear flows does not guarantee subsequent monolithic collapse. Our simulations also demonstrate that significant power can (if present initially) be maintained with negligible dissipation in large-scale compressive modes of a magnetic thin sheet, in the limit of perfect flux freezing.

Shantanu Basu; Glenn E. Ciolek; Wolf Dapp; James Wurster

2009-01-14T23:59:59.000Z

83

Re-Regulating the Mexican Gulf  

E-Print Network [OSTI]

energy sovereignty as manifest in Venezuela’s recent endorsement of Petroleo Caribe as well as in Bolivia’

Zalik, Anna

2006-01-01T23:59:59.000Z

84

Downregualtion of dynamin-related protein 1 attenuates glutamate-induced excitotoxicity via regulating mitochondrial function in a calcium dependent manner in HT22 cells  

SciTech Connect (OSTI)

Highlights: •Downregulation of Drp-1 attenuates glutamate-induced excitotoxicity. •Downregulation of Drp-1 inhibits glutamate-induced apoptosis. •Downregulation of Drp-1 reduces glutamate-induced mitochondrial dysfunction. •Downregulation of Drp-1 preserves intracellular calcium homeostasis. -- Abstract: Glutamate-mediated excitotoxicity is involved in many acute and chronic brain diseases. Dynamin related protein 1 (Drp-1), one of the GTPase family of proteins that regulate mitochondrial fission and fusion balance, is associated with apoptotic cell death in cancer and neurodegenerative diseases. Here we investigated the effect of downregulating Drp-1 on glutamate excitotoxicity-induced neuronal injury in HT22 cells. We found that downregulation of Drp-1 with specific small interfering RNA (siRNA) increased cell viability and inhibited lactate dehydrogenase (LDH) release after glutamate treatment. Downregulation of Drp-1 also inhibited an increase in the Bax/Bcl-2 ratio and cleavage of caspase-9 and caspase-3. Drp-1 siRNA transfection preserved the mitochondrial membrane potential (MMP), reduced cytochrome c release, enhanced ATP production, and partly prevented mitochondrial swelling. In addition, Drp-1 knockdown attenuated glutamate-induced increases of cytoplasmic and mitochondrial Ca{sup 2+}, and preserved the mitochondrial Ca{sup 2+} buffering capacity after excitotoxicity. Taken together, these results suggest that downregulation of Drp-1 protects HT22 cells against glutamate-induced excitatory damage, and this neuroprotection may be dependent at least in part on the preservation of mitochondrial function through regulating intracellular calcium homeostasis.

Zhang, Chi; Yuan, Xian-rui; Li, Hao-yu; Zhao, Zi-jin; Liao, Yi-wei; Wang, Xiang-yu; Su, Jun; Sang, Shu-shan; Liu, Qing, E-mail: xiangyaliuqing@163.com

2014-01-03T23:59:59.000Z

85

Les risques sismiques Mrida (Venezuela). Pour une association des communauts la prvention de catastrophe dans les  

E-Print Network [OSTI]

Les risques sismiques à Mérida (Venezuela). Pour une association des communautés à la prévention de louest) et de Trujillo (à lest) sont les trois états andins du Venezuela. Ils occupent le tracé de la cordillère andine du Venezuela qui se dégrade au nord-est dans létat de Lara en une transition montagneuse

Paris-Sud XI, Université de

86

Au-del de la Revolucin ! Un regard critique sur le Venezuela contemporain  

E-Print Network [OSTI]

1 Au-delà de la ¡ Revolución ! Un regard critique sur le Venezuela contemporain Julien REBOTIER du Venezuela, affecte á différents degrés la géopolitique régionale, mais peine á consacrer les cambia la cara de Venezuela, modifica la geopolítica regional a diferentes grados, pero no logra que

Paris-Sud XI, Université de

87

Sesin 3 -Sistemas Distribuidos y Aplicaciones Mdicas 89 Escuela de Computacin Universidad Central de Venezuela UCV  

E-Print Network [OSTI]

Central de Venezuela UCV #12;II Simposio Científico y Tecnológico en Computación 201290 Escuela de Computación Universidad Central de Venezuela UCV #12;Sesión 3 - Sistemas Distribuidos y Aplicaciones Médicas 91 Escuela de Computación Universidad Central de Venezuela UCV #12;II Simposio Científico y

Coto, Ernesto

88

E-Print Network 3.0 - amazonas state venezuela Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Summary: Fig. 6).--VENEZUELA: Amazonas, BuenaVista, RioCasiquiare (Sanborn, 1937). SURINAME: Para, Zanderij... . Marginal localities of record (South America only, see Fig....

89

E-Print Network 3.0 - aragua state venezuela Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

State in Brazil (Fig. 3; Cabrera 1957; Eisenberg and Redford 1999; Jones... , in Suriname, Peru, and Venezuela (Guerrero 1996; Wenzel 1976). BEHAVIOR. In French Guiana,...

90

E-Print Network 3.0 - area east venezuela Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Effect Summary: , 2008. Municipalities across Venezuela, from Caracas to the smallest rural areas, remain covered... david rockefeller center for latin american studies, Harvard...

91

Curcumin Regulates Low-Linear Energy Transfer {gamma}-Radiation-Induced NF{kappa}B-Dependent Telomerase Activity in Human Neuroblastoma Cells  

SciTech Connect (OSTI)

Purpose: We recently reported that curcumin attenuates ionizing radiation (IR)-induced survival signaling and proliferation in human neuroblastoma cells. Also, in the endothelial system, we have demonstrated that NF{kappa}B regulates IR-induced telomerase activity (TA). Accordingly, we investigated the effect of curcumin in inhibiting IR-induced NF{kappa}B-dependent hTERT transcription, TA, and cell survival in neuroblastoma cells. Methods and Materials: SK-N-MC or SH-SY5Y cells exposed to IR and treated with curcumin (10-100 nM) with or without IR were harvested after 1 h through 24 h. NF{kappa}B-dependent regulation was investigated either by luciferase reporter assays using pNF{kappa}B-, pGL3-354-, pGL3-347-, or pUSE-I{kappa}B{alpha}-Luc, p50/p65, or RelA siRNA-transfected cells. NF{kappa}B activity was analyzed using an electrophoretic mobility shift assay and hTERT expression using the quantitative polymerase chain reaction. TA was determined using the telomerase repeat amplification protocol assay and cell survival using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltertrazolium bromide and clonogenic assay. Results: Curcumin profoundly inhibited IR-induced NF{kappa}B. Consequently, curcumin significantly inhibited IR-induced TA and hTERT mRNA at all points investigated. Furthermore, IR-induced TA is regulated at the transcriptional level by triggering telomerase reverse transcriptase (TERT) promoter activation. Moreover, NF{kappa}B becomes functionally activated after IR and mediates TA upregulation by binding to the {kappa}B-binding region in the promoter region of the TERT gene. Consistently, elimination of the NF{kappa}B-recognition site on the telomerase promoter or inhibition of NF{kappa}B by the I{kappa}B{alpha} mutant compromises IR-induced telomerase promoter activation. Significantly, curcumin inhibited IR-induced TERT transcription. Consequently, curcumin inhibited hTERT mRNA and TA in NF{kappa}B overexpressed cells. Furthermore, curcumin enhanced the IR-induced inhibition of cell survival. Conclusions: These results strongly suggest that curcumin inhibits IR-induced TA in an NF{kappa}B dependent manner in human neuroblastoma cells.

Aravindan, Natarajan, E-mail: naravind@ouhsc.ed [Department of Radiation Oncology, University of Oklahoma Health Sciences Center, Oklahoma City, OK (United States); Veeraraghavan, Jamunarani; Madhusoodhanan, Rakhesh; Herman, Terence S. [Department of Radiation Oncology, University of Oklahoma Health Sciences Center, Oklahoma City, OK (United States); Natarajan, Mohan [Department of Otolaryngology, Head and Neck Surgery, University of Texas Health Sciences Center at San Antonio, San Antonio, TX (United States)

2011-03-15T23:59:59.000Z

92

DHA down-regulates phenobarbital-induced cytochrome P450 2B1 gene expression in rat primary hepatocytes by attenuating CAR translocation  

SciTech Connect (OSTI)

The constitutive androstane receptor (CAR) plays an important role in regulating the expression of detoxifying enzymes, including cytochrome P450 2B (CYP 2B). Phenobarbital (PB) induction of human CYP 2B6 and mouse CYP 2b10 has been shown to be mediated by CAR. Our previous study showed that PB-induced CYP 2B1 expression in rat primary hepatocytes is down-regulated by both n-6 and n-3 polyunsaturated fatty acids (PUFAs), especially docosahexaenoic acid (DHA); however, the mechanism for this down-regulation by DHA was previously unknown. The objective of the present study was to determine whether change in CAR translocation is involved in the down-regulation by n-6 and n-3 PUFAs of PB-induced CYP 2B1 expression in rat primary hepatocytes. We used 100 {mu}M arachidonic acid, linoleic acid, eicosapentaenoic acid, and DHA to test this hypothesis. PB triggered the translocation of CAR from the cytosol into the nucleus in a dose-dependent and time-dependent manner in our hepatocyte system, and the CAR distribution in rat primary hepatocytes was significantly affected by DHA. DHA treatment decreased PB-inducible accumulation of CAR in the nuclear fraction and increased it in the cytosolic fraction in a dose-dependent manner. The down-regulation of CYP 2B1 expression by DHA occurred in a dose-dependent manner, and a similar pattern was found for the nuclear accumulation of CAR. The results of immunoprecipitation showed a CAR/RXR heterodimer bound to nuclear receptor binding site 1 (NR-1) of the PB-responsive enhancer module (PBREM) of the CYP 2B1gene. The EMSA results showed that PB-induced CAR binding to NR-1 was attenuated by DHA. Taken together, these results suggest that attenuation of CAR translocation and decreased subsequent binding to NR-1 are involved in DHA's down-regulation of PB-induced CYP 2B1 expression.

Li, C.-C.; Lii, C.-K.; Liu, K.-L. [Department of Nutrition, Chung Shan Medical University, Taichung, Taiwan (China); Yang, J.-J. [School of Dentistry, Chung Shan Medical University, Taichung, Taiwan (China); Chen, H.-W. [Department of Nutrition, Chung Shan Medical University, Taichung, Taiwan (China)], E-mail: hawwen@csmu.edu.tw

2007-12-15T23:59:59.000Z

93

Nickel-induced down-regulation of {Delta}Np63 and its role in the proliferation of keratinocytes  

SciTech Connect (OSTI)

Epidemiological, animal, and cell studies have demonstrated that nickel compounds are human carcinogens. The mechanisms of their carcinogenic actions remain to be investigated. p63, a close homologue of the p53 tumor suppressor protein, has been linked to cell fate determination and/or maintenance of self-renewing populations in several epithelial tissues, including skin, mammary gland, and prostate. {Delta}Np63, a dominant negative isoform of p63, is amplified in a variety of epithelial tumors including squamous cell carcinomas and carcinomas of the prostate and mammary glands. The present study shows that nickel suppressed {Delta}Np63 expression in a short-time treatment (up to 48 h). Nickel treatment caused activation of NF-{kappa}B. Blockage of NF-{kappa}B partially reversed nickel-induced {Delta}Np63 suppression. Nickel decreased interferon regulatory factor (IRF) 3 and IRF7, IKK{epsilon}, and Sp100. Over-expression of IRF3 increased {Delta}Np63 expression suppressed by nickel. Nickel was able to activate p21, and its activation was offset by the over-expression of {Delta}Np63. In turn, elevated p63 expression counteracted the ability of nickel to restrict cell growth. The present study demonstrated that nickel decreased interferon regulatory proteins IRF3 and IRF7, and activated NF-{kappa}B, resulting in {Delta}Np63 suppression and then p21 up-regulation. {Delta}Np63 plays an important role in nickel-induced cell proliferation. - Highlights: > Ni suppressed {Delta}Np63 expression in HaCat cells. > Ni activated NF-{kappa}B, decreased expressions of IRF3 and IRF7, IKK{epsilon}, and Sp100. > Over-expression of IRF3 increased {Delta}Np63 expression suppressed by Ni. > Ni activated p21, and its activation was offset by over-expression of {Delta}Np63. > Elevated p63 expression counteracted the ability of nickel to restrict cell growth.

Zhang Zhuo, E-mail: zhuo.zhang@uky.edu [Department of Preventive Medicine and Environmental Health, University of Kentucky, 121 Washington Avenue, Lexington, KY 40536 (United States); Li Wenqi [Department of Preventive Medicine and Environmental Health, University of Kentucky, 121 Washington Avenue, Lexington, KY 40536 (United States); Cheng Senping [Graduate Center for Toxicology, University of Kentucky, 1095 VA Drive, Lexington, KY 40536 (United States); Yao Hua [Department of Stomatology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003 (China); Zhang Fan; Chang Qingshan [Graduate Center for Toxicology, University of Kentucky, 1095 VA Drive, Lexington, KY 40536 (United States); Ke Zunji [Department of Internal Medicine, University of Kentucky, 800 Rose Street, Lexington, KY 40536 (United States); Wang Xin; Son, Young-Ok [Graduate Center for Toxicology, University of Kentucky, 1095 VA Drive, Lexington, KY 40536 (United States); Luo Jia [Department of Internal Medicine, University of Kentucky, 800 Rose Street, Lexington, KY 40536 (United States); Shi Xianglin [Graduate Center for Toxicology, University of Kentucky, 1095 VA Drive, Lexington, KY 40536 (United States)

2011-06-15T23:59:59.000Z

94

Clay mineralogy of surface sediments as a tool for deciphering river contributions to the Cariaco Basin (Venezuela)  

E-Print Network [OSTI]

Basin (Venezuela) V. Bout-Roumazeilles,1 A. Riboulleau,1 E. Armynot du Châtelet,1 L. Lorenzoni,3 N for deciphering river contributions to the Cariaco Basin (Venezuela), J. Geophys. Res. Oceans, 118, doi:10

Meyers, Steven D.

95

Seismic Anisotropy and Mantle flow beneath Western Venezuela Jeniffer Masy,1 Fenglin Niu1 and Alan Levander1  

E-Print Network [OSTI]

Seismic Anisotropy and Mantle flow beneath Western Venezuela Jeniffer Masy,1 Fenglin Niu1 and Alan the Caribbean (CAR) and South American (SA) plates in western Venezuela is a wide area where a variety- mic Network of Venezuela. Yellow and red symbols represent temporal de- ployments under the first

Alvarez, Pedro J.

96

Two new Fusicoccum species from Acacia and Eucalyptus in Venezuela, based on morphology and DNA sequence data  

E-Print Network [OSTI]

Two new Fusicoccum species from Acacia and Eucalyptus in Venezuela, based on morphology and DNA in Venezuela, based on morphological features in culture and comparisons of DNA se- quence data. The two taxa y Ambientales, Universidad de los Andes, Me´rida 5101-A, Venezuela. available at www

97

Expression of the chaplin and rodlin hydrophobic sheath proteins in Streptomyces venezuelae is controlled by sBldN  

E-Print Network [OSTI]

Expression of the chaplin and rodlin hydrophobic sheath proteins in Streptomyces venezuelae) genes by exploiting a new model species, Streptomyces venezuelae, which sporulates in liquid culture discussed in this report, Streptomy- ces venezuelae has two long chaplins (ChpB and ChpC) and four short

Buttner, Mark

98

Comparison of species-specific oxygen isotope paleotemperature equations: Sensitivity analysis using planktonic foraminifera from the Cariaco Basin, Venezuela  

E-Print Network [OSTI]

using planktonic foraminifera from the Cariaco Basin, Venezuela Katherine E. Wejnert a, , Robert C, Venezuela a b s t r a c ta r t i c l e i n f o Article history: Received 6 December 2011 Received in revised biweekly sediment trap samples collected in Cariaco Basin, Venezuela between 2003 and 2008. Sixteen

Meyers, Steven D.

99

EL IMPACTO DEL CONFLICTO POLTICO SOBRE LAS ORGANIZACIONES DE LA SOCIEDAD CIVIL EN VENEZUELA: EL DILEMA ENTRE PARTICIPACIN Y REPRESENTACIN.  

E-Print Network [OSTI]

EL IMPACTO DEL CONFLICTO POLÍTICO SOBRE LAS ORGANIZACIONES DE LA SOCIEDAD CIVIL EN VENEZUELA: EL Universidad Central de Venezuela gomezcal@cantv.net RESUMEN: En los años recientes, la pérdida de legitimidad, conflicto político, Venezuela #12;INTRODUCCI�N En este trabajo intentamos analizar algunos de los impactos

Paris-Sud XI, Université de

100

Lactoferrin inhibits dexamethasone-induced chondrocyte impairment from osteoarthritic cartilage through up-regulation of extracellular signal-regulated kinase 1/2 and suppression of FASL, FAS, and Caspase 3  

SciTech Connect (OSTI)

Highlights: •Dex exerts dose-dependant inhibition of HACs viability and induction of apoptosis. •Dex-induced impairment of chondrocytes was attenuated by rhLF. •ERK and FASL/FAS signaling are involved in the effects of rhLF. •OA patients with glucocorticoid-induced cartilage damage may benefit from treatment with rhLF. -- Abstract: Dexamethasone (Dex) is commonly used for osteoarthritis (OA) with excellent anti-inflammatory and analgesic effect. However, Dex also has many side effects following repeated use over prolonged periods mainly through increasing apoptosis and inhibiting proliferation. Lactoferrin (LF) exerts significantly anabolic effect on many cells and little is known about its effect on OA chondrocytes. Therefore, the aim of this study is to investigate whether LF can inhibit Dex-induced OA chondrocytes apoptosis and explore its possible molecular mechanism involved in. MTT assay was used to determine the optimal concentration of Dex and recombinant human LF (rhLF) on chondrocytes at different time and dose points. Chondrocytes were then stimulated with Dex in the absence or presence of optimal concentration of rhLF. Cell proliferation and viability were evaluated using MTT and LIVE/DEAD assay, respectively. Cell apoptosis was evaluated by multi-parameter apoptosis assay kit using both confocal microscopy and flow cytometry, respectively. The expression of extracellular signal-regulated kinase (ERK), FAS, FASL, and Caspase-3 (CASP3) at the mRNA and protein levels were examined by real-time polymerase chain reaction (PCR) and immunocytochemistry, respectively. The optimal concentration of Dex (25 ?g/ml) and rhLF (200 ?g/ml) were chosen for the following experiments. rhLF significantly reversed the detrimental effect of Dex on chondrocytes proliferation, viability, and apoptosis. In addition, rhLF significantly prevented Dex-induced down-regulation of ERK and up-regulation of FAS, FASL, and CASP3. These findings demonstrated that rhLF acts as an anabolic effect on chondrocytes through significantly reversing Dex-induced chondrocytes apoptosis. This study may contribute to further investigating the clinical application of LF on OA.

Tu, Yihui [Department of Orthopaedics, Yangpu District Central Hospital Affiliated to Tongji University School of Medicine, 450 Tengyue Road, Shanghai (China)] [Department of Orthopaedics, Yangpu District Central Hospital Affiliated to Tongji University School of Medicine, 450 Tengyue Road, Shanghai (China); Xue, Huaming [Department of Orthopaedics, Yangpu District Central Hospital Affiliated to Tongji University School of Medicine, 450 Tengyue Road, Shanghai (China) [Department of Orthopaedics, Yangpu District Central Hospital Affiliated to Tongji University School of Medicine, 450 Tengyue Road, Shanghai (China); Institute of Life Science, College of Medicine, Swansea University, Singleton Park (United Kingdom); Francis, Wendy [Institute of Life Science, College of Medicine, Swansea University, Singleton Park (United Kingdom)] [Institute of Life Science, College of Medicine, Swansea University, Singleton Park (United Kingdom); Davies, Andrew P. [Department of Orthopaedics and Trauma, Moriston Hospital, Swansea (United Kingdom)] [Department of Orthopaedics and Trauma, Moriston Hospital, Swansea (United Kingdom); Pallister, Ian; Kanamarlapudi, Venkateswarlu [Institute of Life Science, College of Medicine, Swansea University, Singleton Park (United Kingdom)] [Institute of Life Science, College of Medicine, Swansea University, Singleton Park (United Kingdom); Xia, Zhidao, E-mail: zhidao.xia@gmail.com [Institute of Life Science, College of Medicine, Swansea University, Singleton Park (United Kingdom)] [Institute of Life Science, College of Medicine, Swansea University, Singleton Park (United Kingdom)

2013-11-08T23:59:59.000Z

Note: This page contains sample records for the topic "venezuela regulation induced" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


101

Moderate extracellular acidification inhibits capsaicin-induced cell death through regulating calcium mobilization, NF-{kappa}B translocation and ROS production in synoviocytes  

SciTech Connect (OSTI)

Highlights: Black-Right-Pointing-Pointer Moderate extracellular acidification regulates intracellular Ca{sup 2+} mobilization. Black-Right-Pointing-Pointer Moderate acidification activates NF-{kappa}B nuclear translocation in synoviocytes. Black-Right-Pointing-Pointer Moderate acidification depresses the ROS production induced by capsaicin. Black-Right-Pointing-Pointer Moderate acidification inhibits capsaicin-caused synoviocyte death. -- Abstract: We previously show the expression of transient receptor potential vanilloid 1 (TRPV1) in primary synoviocytes from collagen-induced arthritis (CIA) rats. Capsaicin and lowered extracellular pH from 7.4 to 5.5 induce cell death through TRPV1-mediated Ca{sup 2+} entry and reactive oxygen species (ROS) production. However, under the pathological condition in rheumatoid arthritis, the synovial fluid is acidified to a moderate level (about pH 6.8). In the present study, we examined the effects of pH 6.8 on the TRPV1-mediated cell death. Our finding is different or even opposite from what was observed at pH 5.5. We found that the moderate extracellular acidification (from pH 7.4 to 6.8) inhibited the capsaicin-induced Ca{sup 2+} entry through attenuating the activity of TRPV1. In the mean time, it triggered a phospholipse C (PLC)-related Ca{sup 2+} release from intracellular stores. The nuclear translocation of NF-{kappa}B was found at pH 6.8, and this also depends on PLC activation. Moreover, the capsaicin-evoked massive ROS production and cell death were depressed at pH 6.8, both of which are dependent on the activation of PLC and NF-{kappa}B. Taken together, these results suggested that the moderate extracellular acidification inhibited the capsaicin-induced synoviocyte death through regulating Ca{sup 2+} mobilization, activating NF-{kappa}B nuclear translocation and depressing ROS production.

Hu, Fen; Yang, Shuang; Zhao, Dan; Zhu, Shuyan; Wang, Yuxiang [Department of Biophysics, School of Physics and Key Laboratory of Bioactive Materials of Education Ministry, Nankai University, Tianjin 300071 (China)] [Department of Biophysics, School of Physics and Key Laboratory of Bioactive Materials of Education Ministry, Nankai University, Tianjin 300071 (China); Li, Junying, E-mail: jyli04@nankai.edu.cn [Department of Biophysics, School of Physics and Key Laboratory of Bioactive Materials of Education Ministry, Nankai University, Tianjin 300071 (China)] [Department of Biophysics, School of Physics and Key Laboratory of Bioactive Materials of Education Ministry, Nankai University, Tianjin 300071 (China)

2012-07-20T23:59:59.000Z

102

Copper deficiency alters cell bioenergetics and induces mitochondrial fusion through up-regulation of MFN2 and OPA1 in erythropoietic cells  

SciTech Connect (OSTI)

Highlights: •In copper deficiency, cell proliferation is not affected. In turn, cell differentiation is impaired. •Enlarged mitochondria are due to up-regulation of MNF2 and OPA1. •Mitochondria turn off respiratory chain and ROS production. •Energy metabolism switch from mitochondria to glycolysis. -- Abstract: Copper is essential in cell physiology, participating in numerous enzyme reactions. In mitochondria, copper is a cofactor for respiratory complex IV, the cytochrome c oxidase. Low copper content is associated with anemia and the appearance of enlarged mitochondria in erythropoietic cells. These findings suggest a connection between copper metabolism and bioenergetics, mitochondrial dynamics and erythropoiesis, which has not been explored so far. Here, we describe that bathocuproine disulfonate-induced copper deficiency does not alter erythropoietic cell proliferation nor induce apoptosis. However it does impair erythroid differentiation, which is associated with a metabolic switch between the two main energy-generating pathways. That is, from mitochondrial function to glycolysis. Switching off mitochondria implies a reduction in oxygen consumption and ROS generation along with an increase in mitochondrial membrane potential. Mitochondrial fusion proteins MFN2 and OPA1 were up-regulated along with the ability of mitochondria to fuse. Morphometric analysis of mitochondria did not show changes in total mitochondrial biomass but rather bigger mitochondria because of increased fusion. Similar results were also obtained with human CD34+, which were induced to differentiate into red blood cells. In all, we have shown that adequate copper levels are important for maintaining proper mitochondrial function and for erythroid differentiation where the energy metabolic switch plus the up-regulation of fusion proteins define an adaptive response to copper deprivation to keep cells alive.

Bustos, Rodrigo I.; Jensen, Erik L.; Ruiz, Lina M.; Rivera, Salvador; Ruiz, Sebastián [Center for Biomedical Research, Faculty of Biological Sciences and Faculty of Medicine, Universidad Andres Bello, Santiago (Chile)] [Center for Biomedical Research, Faculty of Biological Sciences and Faculty of Medicine, Universidad Andres Bello, Santiago (Chile); Simon, Felipe; Riedel, Claudia [Center for Biomedical Research, Faculty of Biological Sciences and Faculty of Medicine, Universidad Andres Bello, Santiago (Chile) [Center for Biomedical Research, Faculty of Biological Sciences and Faculty of Medicine, Universidad Andres Bello, Santiago (Chile); Millennium Institute of Immunology and Immunotherapy, Santiago (Chile); Ferrick, David [Seahorse Bioscience, Billerica, MA (United States)] [Seahorse Bioscience, Billerica, MA (United States); Elorza, Alvaro A., E-mail: aelorza@unab.cl [Center for Biomedical Research, Faculty of Biological Sciences and Faculty of Medicine, Universidad Andres Bello, Santiago (Chile); Millennium Institute of Immunology and Immunotherapy, Santiago (Chile)

2013-08-02T23:59:59.000Z

103

E-Print Network 3.0 - alta guajira venezuela Sample Search Results  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

on taxes paid by its NOC is second only to Venezuela in the Western Hemisphere. Pemex has had Source: Texas at Austin, University of - George E. Brown, Jr. Network for...

104

Fertility and rate of growth in a beef cattle herd in the 0rient of Venezuela  

E-Print Network [OSTI]

to express his utmost gratitude to Venezuela for giving him the opportunity to work toward the Master of Science degree through a scholarship of the Consejo Nacional de Investigaciones Cientzficas (CONICIT) and the Universidad de Oriente. Special...

Gonzalez Crespo, Justo Nicolas

1978-01-01T23:59:59.000Z

105

Review of the Berosus Leach of Venezuela (Coleoptera, Hydrophilidae, Berosini) with description of fourteen new species  

E-Print Network [OSTI]

The species of the water scavenger beetle genus Berosus Leach occurring in Venezuela are reviewed. Thirty-six species are recorded, including fifteen new species, fourteen of which are described here as new: Berosus aragua sp. n., Berosus...

Oliva, Adriana; Short, Andrew E. Z.

2012-07-06T23:59:59.000Z

106

A revision of the Larainae (Coleoptera, Elmidae) of Venezuela, with description of nine new species  

E-Print Network [OSTI]

The species of the riffle beetle subfamily Larainae occurring in Venezuela are revised. Examination of 756 specimens yielded 22 species in nine genera occurring throughout the country. Seven species are newly recorded from the country: Phanoceroides...

Maier, Crystal A.

2013-09-05T23:59:59.000Z

107

Library Regulations Library Regulations  

E-Print Network [OSTI]

Library Regulations 2012-13 Library Regulations UNIVERSITY OF BIRMINGHAM REGULATIONS LIBRARY REGULATIONS Preamble: The Library Regulations apply to all users of library facilities managed on behalf of the University by Library Services, and thus there are sections that apply also to non- members of the University

Birmingham, University of

108

Characterization of Habitat for Hawksbill Turtle (Eretmochelys imbricata) in Los Roques Archipelago National Park, Venezuela  

E-Print Network [OSTI]

CHARACTERIZATION OF HABITAT FOR HAWKSBILL TURTLE (Eretmochelys imbricata) IN LOS ROQUES ARCHIPELAGO NATIONAL PARK, VENEZUELA A Thesis by LUCIANA ESTELA HUNT Submitted to the Office of Graduate Studies of Texas A&M University..., VENEZUELA A Thesis by LUCIANA ESTELA HUNT Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE Approved by: Chair of Committee, William D. Heyman...

Hunt, Luciana E.

2010-10-12T23:59:59.000Z

109

EGCG protects endothelial cells against PCB 126-induced inflammation through inhibition of AhR and induction of Nrf2-regulated genes  

SciTech Connect (OSTI)

Tea flavonoids such as epigallocatechin gallate (EGCG) protect against vascular diseases such as atherosclerosis via their antioxidant and anti-inflammatory functions. Persistent and widespread environmental pollutants, including polychlorinated biphenyls (PCB), can induce oxidative stress and inflammation in vascular endothelial cells. Even though PCBs are no longer produced, they are still detected in human blood and tissues and thus considered a risk for vascular dysfunction. We hypothesized that EGCG can protect endothelial cells against PCB-induced cell damage via its antioxidant and anti-inflammatory properties. To test this hypothesis, primary vascular endothelial cells were pretreated with EGCG, followed by exposure to the coplanar PCB 126. Exposure to PCB 126 significantly increased cytochrome P450 1A1 (Cyp1A1) mRNA and protein expression and superoxide production, events which were significantly attenuated following pretreatment with EGCG. Similarly, EGCG also reduced DNA binding of NF-?B and downstream expression of inflammatory markers such as monocyte chemotactic protein-1 (MCP-1) and vascular cell adhesion protein-1 (VCAM-1) after PCB exposure. Furthermore, EGCG decreased endogenous or base-line levels of Cyp1A1, MCP-1 and VCAM-1 in endothelial cells. Most of all, treatment of EGCG upregulated expression of NF-E2-related factor 2 (Nrf2)-controlled antioxidant genes, including glutathione S transferase (GST) and NAD(P)H:quinone oxidoreductase 1 (NQO1), in a dose-dependent manner. In contrast, silencing of Nrf2 increased Cyp1A1, MCP-1 and VCAM-1 and decreased GST and NQO1 expression, respectively. These data suggest that EGCG can inhibit AhR regulated genes and induce Nrf2-regulated antioxidant enzymes, thus providing protection against PCB-induced inflammatory responses in endothelial cells. -- Highlights: ? PCBs cause endothelial inflammation and subsequent atherosclerosis. ? Nutrition can modulate toxicity by environmental pollutants. ? We demonstrated that EGCG can decrease PCB-induced inflammation. ? EGCG protection was via inhibition of AhR and induction of Nrf2 regulatory genes.

Han, Sung Gu [Superfund Research Program, University of Kentucky, Lexington, KY 40536 (United States) [Superfund Research Program, University of Kentucky, Lexington, KY 40536 (United States); Department of Animal and Food Sciences, College of Agriculture, University of Kentucky, Lexington, KY 40536 (United States); Han, Seong-Su [Department of Pathology, College of Medicine, University of Iowa, Iowa City, IA 52242 (United States)] [Department of Pathology, College of Medicine, University of Iowa, Iowa City, IA 52242 (United States); Toborek, Michal [Department of Neurosurgery, University of Kentucky, Lexington, KY 40536 (United States)] [Department of Neurosurgery, University of Kentucky, Lexington, KY 40536 (United States); Hennig, Bernhard, E-mail: bhennig@uky.edu [Superfund Research Program, University of Kentucky, Lexington, KY 40536 (United States) [Superfund Research Program, University of Kentucky, Lexington, KY 40536 (United States); Department of Animal and Food Sciences, College of Agriculture, University of Kentucky, Lexington, KY 40536 (United States)

2012-06-01T23:59:59.000Z

110

Roles of Sensory Nerves in the Regulation of Radiation-Induced Structural and Functional Changes in the Heart  

SciTech Connect (OSTI)

Purpose: Radiation-induced heart disease (RIHD) is a chronic severe side effect of radiation therapy of intrathoracic and chest wall tumors. The heart contains a dense network of sensory neurons that not only are involved in monitoring of cardiac events such as ischemia and reperfusion but also play a role in cardiac tissue homeostasis, preconditioning, and repair. The purpose of this study was to examine the role of sensory nerves in RIHD. Methods and Materials: Male Sprague-Dawley rats were administered capsaicin to permanently ablate sensory nerves, 2 weeks before local image-guided heart x-ray irradiation with a single dose of 21 Gy. During the 6 months of follow-up, heart function was assessed with high-resolution echocardiography. At 6 months after irradiation, cardiac structural and molecular changes were examined with histology, immunohistochemistry, and Western blot analysis. Results: Capsaicin pretreatment blunted the effects of radiation on myocardial fibrosis and mast cell infiltration and activity. By contrast, capsaicin pretreatment caused a small but significant reduction in cardiac output 6 months after irradiation. Capsaicin did not alter the effects of radiation on cardiac macrophage number or indicators of autophagy and apoptosis. Conclusions: These results suggest that sensory nerves, although they play a predominantly protective role in radiation-induced cardiac function changes, may eventually enhance radiation-induced myocardial fibrosis and mast cell activity.

Sridharan, Vijayalakshmi; Tripathi, Preeti [Department of Pharmaceutical Sciences, Division of Radiation Health, University of Arkansas for Medical Sciences, Little Rock, Arkansas (United States); Sharma, Sunil [Department of Radiation Oncology, Division of Radiation Health, University of Arkansas for Medical Sciences, Little Rock, Arkansas (United States); Moros, Eduardo G. [Department of Radiation Oncology, Moffitt Cancer Center and Research Institute, Tampa, Florida (United States); Zheng, Junying [Department of Pharmaceutical Sciences, Division of Radiation Health, University of Arkansas for Medical Sciences, Little Rock, Arkansas (United States); Hauer-Jensen, Martin [Department of Pharmaceutical Sciences, Division of Radiation Health, University of Arkansas for Medical Sciences, Little Rock, Arkansas (United States); Surgical Service, Central Arkansas Veterans Healthcare System, Little Rock, Arkansas (United States); Boerma, Marjan, E-mail: mboerma@uams.edu [Department of Pharmaceutical Sciences, Division of Radiation Health, University of Arkansas for Medical Sciences, Little Rock, Arkansas (United States)

2014-01-01T23:59:59.000Z

111

Vertical fluxes of particulate biogenic material through the euphotic and twilight zones in the Cariaco Basin, Venezuela  

E-Print Network [OSTI]

in the Cariaco Basin, Venezuela Enrique Montes a,n , Frank Muller-Karger a , Robert Thunell b , David Hollander, Venezuela a r t i c l e i n f o Article history: Received 2 May 2011 Received in revised form 5 May 2012

Meyers, Steven D.

112

Comparison of Petrophysical Rock Types from Core and Well-logs using Post-stack 3D Seismic Data: Field Example from Maracaibo-Venezuela  

E-Print Network [OSTI]

: Field Example from Maracaibo-Venezuela Francisco Cheng* and Kumar Ramachandran, The University of Tulsa in an area located on the West side of Lake Maracaibo-Venezuela. The calculated petrophysical rock types were Description The study area is located on the West side of Lake Maracaibo-Venezuela, in shallow, transition

Ramachandran, Kumar

113

CONDICIONES DE TRABAJO EN VENEZUELA EN EL PERODO 1999-2005: ELEMENTOS PARA UN BALANCE DE LA CUESTIN LABORAL EN EL PROCESO BOLIVARIANO  

E-Print Network [OSTI]

CONDICIONES DE TRABAJO EN VENEZUELA EN EL PERÍODO 1999-2005: ELEMENTOS PARA UN BALANCE DE LA; informalidad; desempleo; salarios. #12;1. Introducción: el proyecto económico del proceso bolivariano Venezuela vigor de la nueva Constitución de 1999, en Venezuela se ha abierto un espacio político fabuloso donde el

Paris-Sud XI, Université de

114

A social learning approach to the study of intrastate political violence: the case of Venezuela  

E-Print Network [OSTI]

dictators for Venezuela for a period of fifty-nine years. Juan Vicente Gomez was literally the caud111o to end all caudillos in Venezuela. Gomez, acting as vice- president in the Castro regime, usurped the presid. ency in 1908. 23 The regime established... by Gomez ended the system in wnich the national caudillo was merely the foremost member of a "pecking order" of caudillos. He defeated regional, state and local caudi. llos and organized a national army of profess1onal officers trained in the Prussian...

Roberts, Sherman Douglas

1971-01-01T23:59:59.000Z

115

Regulating energy transfer of excited carriers and the case for...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Regulating energy transfer of excited carriers and the case for excitation-induced hydrogen dissociation on hydrogenated Regulating energy transfer of excited carriers and the case...

116

Risk prevention and policy formulation : responding to the 1999 mud-floods catastrophe in El Litoral Central, Venezuela  

E-Print Network [OSTI]

Fifteen days of constant and intense rainfall in Venezuela culminated on December 16 1999, in catastrophic landslides and flooding along 25 miles of the Vargas State coastal strip. This catastrophe ravaged the Caracas ...

Parisca-Blanco, Sonia

2005-01-01T23:59:59.000Z

117

Analysis of reservoir performance and forecasting for the eastern area of the C-2 Reservoir, Lake Maracaibo, Venezuela  

E-Print Network [OSTI]

This research developed a numerical simulation based on the latest reservoir description to evaluate the feasibility of new infill wells to maximize the recovery specifically in the eastern region of the reservoir operated by Petroleos de Venezuela...

Urdaneta Anez, Jackeline C

2001-01-01T23:59:59.000Z

118

Misión Madres Del Barrio: A Bolivarian Social Program Recognizing Housework and Creating A Caring Economy in Venezuela  

E-Print Network [OSTI]

ABSTRACT: This thesis began as a project about Misión Madres del Barrio; and it quickly transformed into a glimpse of the Bolivarian Revolution underway in Venezuela. Misión Madres del Barrio (MMB) is one of the pioneering social programs...

Fischer-Hoffman, Cory

2008-08-20T23:59:59.000Z

119

Identification and characterization of Hydraulic Flow Units in the San Juan Formation, Orocual Field, Venezuela  

E-Print Network [OSTI]

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 CHAPTER VI SUMMARY AND CONCLUSIONS. . 92 6. 1 Summary . 6. 1. 1 Introduction. 6. 1. 2 Objectives of this Study. 6. 1. 3 Results and Summary. 6. 2 Conclusions 6. 3 Recommendations for Future Work . . . 92 92 93 93 94 95 NOMENCLATURE 96... (Head of Department) May 2001 Major Subject: Petroleum Engineering ABSTRACT Identification and Characterization of Hydraulic Flow Units in the San Juan Formation, Orocual Field, Venezuela. (May 2001) Odilia Deghirmandjian, B. S. , Universidad de...

Deghirmandjian, Odilia

2012-06-07T23:59:59.000Z

120

Estradiol-Induced Object Memory Consolidation in Middle-Aged Female Mice Requires Dorsal Hippocampal Extracellular Signal-Regulated Kinase and Phosphatidylinositol 3-Kinase Activation  

E-Print Network [OSTI]

We previously demonstrated that dorsal hippocampal extracellular signal-regulated kinase (ERK) activation is necessary for 17?[beta]-estradiol (E2[E subscript 2]) to enhance novel object recognition in young ovariectomized ...

Lewis, Michael C.

Note: This page contains sample records for the topic "venezuela regulation induced" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


121

Universidad Simn Bolvar, Edif. Energtica, Planta Baja. Valle de Sartenejas, Baruta, Caracas, Edo. Miranda, Venezuela, Telef.: 58 212 906-3708 / 3709 / 3710 / 3711 Fax: 58 212 906-3712 www.ulab.usb.ve  

E-Print Network [OSTI]

. Miranda, Venezuela, 89000 Telef.: 58 212 906-3708 / 3709 / 3710 / 3711 Fax: 58 212 906-3712 www. Miranda, 1080 Venezuela Cód. Doc.: UL02-I03 Fecha: 03/11/2014 #12;

Vásquez, Carlos

122

Lysyl oxidase like 4, a novel target gene of TGF-{beta}1 signaling, can negatively regulate TGF-{beta}1-induced cell motility in PLC/PRF/5 hepatoma cells  

SciTech Connect (OSTI)

Transforming growth factor-{beta}1 (TGF-{beta}1) is a multi-functional cytokine involved in the regulation of cell proliferation, differentiation and extracellular matrix formation. In search for novel genes mediating the TGF-{beta}1 function at downstream signaling, we performed a cDNA microarray analysis and identified 60 genes whose expression is regulated by TGF-{beta}1 in the liver cancer cell line PLC/PRF/5. Among them, we report here lysyl oxidase like 4 (LOXL4) as a novel target of TGF-{beta}1 signaling, and provide experimental evidence for its expression regulation and function. LOXL4 was found to be the only member of LOX family whose expression is induced by TGF-{beta}1 in hepatoma cells. Deletion mapping of the LOXL4 promoter indicated that the TGF-{beta}1 regulation of LOXL4 expression is mediated through the binding of AP1 transcription factor to a conserved region of the promoter. This was confirmed by the chromatin immunoprecipitation assay that captured c-Fos-bound chromatin from TGF-{beta}1-treated cells. Forced expression of LOXL4 in PLC/PRF/5 cells resulted in inhibition of cell motility through Matrigel in the presence of TGF-{beta}1 treatment. In parallel, LOXL4 suppressed the expression of laminins and {alpha}3 integrin and the activity of MMP2. These results suggest that LOXL4 may function as a negative feedback regulator of TGF-{beta}1 in cell invasion by inhibiting the metabolism of extracellular matrix (ECM) components.

Kim, Dong Joon [Medical Genomics Research Center, KRIBB, P.O. Box 115, Yusong, Daejeon 305-806 (Korea, Republic of); College of Pharmacy, Chungnam National University, Daejeon 305-764 (Korea, Republic of); Lee, Dong Chul; Yang, Suk-Jin; Lee, Jung Ju; Bae, Eun Mi; Kim, Dong Min; Min, Sang Hyun; Kim, Soo Jung [Medical Genomics Research Center, KRIBB, P.O. Box 115, Yusong, Daejeon 305-806 (Korea, Republic of); Kang, Dong Chul [Ilsong Institute of Life Science, Hallym University, Anyang 431-060 (Korea, Republic of); Sang, Byung Chan [College of Agricultural Life and Sciences, Chungnam National University, Daejeon 305-764 (Korea, Republic of); Myung, Pyung Keun [College of Pharmacy, Chungnam National University, Daejeon 305-764 (Korea, Republic of); Park, Kyung Chan [Medical Genomics Research Center, KRIBB, P.O. Box 115, Yusong, Daejeon 305-806 (Korea, Republic of)], E-mail: kpark@kribb.re.kr; Yeom, Young Il [Medical Genomics Research Center, KRIBB, P.O. Box 115, Yusong, Daejeon 305-806 (Korea, Republic of)], E-mail: yeomyi@kribb.re.kr

2008-09-05T23:59:59.000Z

123

Overexpression of KAI1 induces autophagy and increases MiaPaCa-2 cell survival through the phosphorylation of extracellular signal-regulated kinases  

SciTech Connect (OSTI)

Research highlights: {yields} We first investigate the effects of KAI1 on autophagy in MiaPaCa-2 cells. {yields} Our findings demonstrate that KAI1 induces autophagy, which in turn inhibits KAI1-induced apoptosis. {yields} This study also supplies a possible novel therapeutic method for the treatment of pancreatic cancer using autophagy inhibitors. -- Abstract: KAI1, a metastasis-suppressor gene belonging to the tetraspanin family, is known to inhibit cancer metastasis without affecting the primary tumorigenicity by inhibiting the epidermal growth factor (EGF) signaling pathway. Recent studies have shown that hypoxic conditions of solid tumors induce high-level autophagy and KAI1 expression. However, the relationship between autophagy and KAI1 remains unclear. By using transmission electron microscopy, confocal microscopy, and Western blotting, we found that KAI1 can induce autophagy in a dose- and time-dependent manner in the human pancreatic cell line MiaPaCa-2. KAI1-induced autophagy was confirmed by the expression of autophagy-related proteins LC3 and Beclin 1. KAI1 induces autophagy through phosphorylation of extracellular signal-related kinases rather than that of AKT. KAI1-induced autophagy protects MiaPaCa-2 cells from apoptosis and proliferation inhibition partially through the downregulation of poly [adenosine diphosphate (ADP)-ribose] polymerase (PARP) cleavage and caspase-3 activation.

Wu, Chun-Yan [State Key Laboratory of Cancer Biology and Institute of Digestive Diseases, Xijing Hospital of Digestive Disease, Fourth Military Medical University, Xi'an 710032 (China) [State Key Laboratory of Cancer Biology and Institute of Digestive Diseases, Xijing Hospital of Digestive Disease, Fourth Military Medical University, Xi'an 710032 (China); Department of Gastroenterology, Shenyang General Hospital of PLA, 83 Wenhua Road, Shenyang 110016 (China); Yan, Jun; Yang, Yue-Feng; Xiao, Feng-Jun; Li, Qing-Fang; Zhang, Qun-Wei; Wang, Li-Sheng [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China)] [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China); Guo, Xiao-Zhong, E-mail: guoxiaozhong1962@163.com [Department of Gastroenterology, Shenyang General Hospital of PLA, 83 Wenhua Road, Shenyang 110016 (China)] [Department of Gastroenterology, Shenyang General Hospital of PLA, 83 Wenhua Road, Shenyang 110016 (China); Wang, Hua, E-mail: wanghua@bmi.ac.cn [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China)] [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China)

2011-01-21T23:59:59.000Z

124

Diverse cell stresses induce unique patterns of tRNA up- and down-regulation: tRNA-seq for quantifying changes in tRNA copy number  

E-Print Network [OSTI]

Emerging evidence points to roles for tRNA modifications and tRNA abundance in cellular stress responses. While isolated instances of stress-induced tRNA degradation have been reported, we sought to assess the effects of ...

Pang, Yan Ling Joy

125

Resumen. La fosa de Cariaco, ubicada al sur del Caribe en el margen continental de Venezuela, ha sido el foco de muchos estudios de relevancia global sobre la qumica de las aguas marinas y la  

E-Print Network [OSTI]

Resumen. La fosa de Cariaco, ubicada al sur del Caribe en el margen continental de Venezuela, ha ("2004"), 161-162: 215-234 #12;216 Características de la fosa de Cariaco, Venezuela Cariaco basin on the continental margin of Venezuela, has been the focus of many marine chemistry and paleoclimatology studies

Meyers, Steven D.

126

FRONTISPIECE. Three-striped Warblers (Basileuterus tristriatus) were studied in the northern Andes of Venezuela. Temperate and tropical parulids differ strongly in life histories. Three-striped Warblers have smaller clutches, longer  

E-Print Network [OSTI]

of Venezuela. Temperate and tropical parulids differ strongly in life histories. Three-striped Warblers have(4):667­678, 2009 BREEDING BIOLOGY OF THE THREE-STRIPED WARBLER IN VENEZUELA: A CONTRAST BETWEEN TROPICAL traits of the Three-striped Warbler (Basileuterus tristriatus) from 146 nests in Venezuela and compare

Martin, Thomas E.

127

Carbachol ameliorates lipopolysaccharide-induced intestinal epithelial tight junction damage by down-regulating NF-{kappa}{beta} and myosin light-chain kinase pathways  

SciTech Connect (OSTI)

Highlights: Black-Right-Pointing-Pointer Carbachol reduced the lipopolysaccharide-induced intestinal barrier breakdown. Black-Right-Pointing-Pointer Carbachol ameliorated the lipopolysaccharide-induced ileal tight junction damage. Black-Right-Pointing-Pointer Carbachol prevented the LPS-induced NF-{kappa}{beta} and myosin light-chain kinase activation. Black-Right-Pointing-Pointer Carbachol exerted its beneficial effects in an {alpha}7 nicotinic receptor-dependent manner. -- Abstract: Carbachol is a cholinergic agonist that protects the intestines after trauma or burn injury. The present study determines the beneficial effects of carbachol and the mechanisms by which it ameliorates the lipopolysaccharide (LPS)-induced intestinal barrier breakdown. Rats were injected intraperitoneally with 10 mg/kg LPS. Results showed that the gut barrier permeability was reduced, the ultrastructural disruption of tight junctions (TJs) was prevented, the redistribution of zonula occludens-1 and claudin-2 proteins was partially reversed, and the nuclear factor-kappa beta (NF-{kappa}{beta}) and myosin light-chain kinase (MLCK) activation in the intestinal epithelium were suppressed after carbachol administration in LPS-exposed rats. Pretreatment with the {alpha}7 nicotinic acetylcholine receptor ({alpha}7nAchR) antagonist {alpha}-bungarotoxin blocked the protective action of carbachol. These results suggested that carbachol treatment can protect LPS-induced intestinal barrier dysfunction. Carbachol exerts its beneficial effect on the amelioration of the TJ damage by inhibiting the NF-{kappa}{beta} and MLCK pathways in an {alpha}7nAchR-dependent manner.

Zhang, Ying [Department of Anesthesia, Critical Care Medicine and Emergency Medicine Center, Zhongnan Hospital, Wuhan University, Wuhan 430071, Hubei Province, People's Republic of China (China)] [Department of Anesthesia, Critical Care Medicine and Emergency Medicine Center, Zhongnan Hospital, Wuhan University, Wuhan 430071, Hubei Province, People's Republic of China (China); Li, Jianguo, E-mail: 2010lijianguo@sina.cn [Department of Anesthesia, Critical Care Medicine and Emergency Medicine Center, Zhongnan Hospital, Wuhan University, Wuhan 430071, Hubei Province, People's Republic of China (China)] [Department of Anesthesia, Critical Care Medicine and Emergency Medicine Center, Zhongnan Hospital, Wuhan University, Wuhan 430071, Hubei Province, People's Republic of China (China)

2012-11-16T23:59:59.000Z

128

{gamma}-aminobutyric acid{sub A} (GABA{sub A}) receptor regulates ERK1/2 phosphorylation in rat hippocampus in high doses of Methyl Tert-Butyl Ether (MTBE)-induced impairment of spatial memory  

SciTech Connect (OSTI)

Experimental and occupational exposure to Methyl Tert-Butyl Ether (MTBE) has been reported to induce neurotoxicological and neurobehavioral effects, such as headache, nausea, dizziness, and disorientation, etc. However, the molecular mechanisms involved in MTBE-induced neurotoxicity are still not well understood. In the present study, we investigated the effects of MTBE on spatial memory and the expression and function of GABA{sub A} receptor in the hippocampus. Our results demonstrated that intraventricular injection of MTBE impaired the performance of the rats in a Morris water maze task, and significantly increased the expression of GABA{sub A} receptor {alpha}1 subunit in the hippocampus. The phosphorylation of ERK1/2 decreased after the MTBE injection. Furthermore, the decreased ability of learning and the reduction of phosphorylated ERK1/2 level of the MTBE-treated rats was partly reversed by bicuculline injected 30 min before the training. These results suggested that MTBE exposure could result in impaired spatial memory. GABA{sub A} receptor may play an important role in the MTBE-induced impairment of learning and memory by regulating the phosphorylation of ERK in the hippocampus.

Zheng Gang; Zhang Wenbin [Department of Occupational and Environmental Health, School of Public Health and Military Preventive Medicine, Fourth Military Medical University, Xi'an 710032 (China); Zhang Yun [465 Hospital, Jilin Medical College, Jilin 132001 (China); Chen Yaoming; Liu Mingchao; Yao Ting; Yang Yanxia; Zhao Fang [Department of Occupational and Environmental Health, School of Public Health and Military Preventive Medicine, Fourth Military Medical University, Xi'an 710032 (China); Li Jingxia; Huang Chuanshu [Nelson Institute of Environmental Medicine, New York University School of Medicine, Tuxedo, New York 10987 (United States); Luo Wenjing [Department of Occupational and Environmental Health, School of Public Health and Military Preventive Medicine, Fourth Military Medical University, Xi'an 710032 (China)], E-mail: luowenj@fmmu.edu.cn; Chen Jingyuan [Department of Occupational and Environmental Health, School of Public Health and Military Preventive Medicine, Fourth Military Medical University, Xi'an 710032 (China)], E-mail: jy_chen@fmmu.edu.cn

2009-04-15T23:59:59.000Z

129

The Long-Run Relationship between Money, Nominal GDP, and the Price Level in Venezuela: 1950 to 1996  

E-Print Network [OSTI]

that structural breaks may be important. Since the economy depends heavily on oil revenue, oil price shocks haveThe Long-Run Relationship between Money, Nominal GDP, and the Price Level in Venezuela: 1950 and the price level in the Venezuelan economy. We apply time-series econometric techniques to annual data

Ahmad, Sajjad

130

Sedimentological characterization of the C2' sequence, Block Lamar field, Maracaibo basin, Venezuela  

SciTech Connect (OSTI)

Through the study of 2,109 ft of core from the Block V-Lamar field, central Maracaibo basin, Venezuela, the environments of deposition were established. The studied interval corresponds to the informal C2 sands of the Misoa Formation (Eocene). Seven different lithofacies were identified and later grouped into three sedimentary units deposited in a general, fluvial-dominated deltaic environment. The organization of the different lithofacies along with palynological data permitted the assignment of lower delta plain, upper delta plain, and, again, lower delta plain for the sedimentary units. The main subenvironments encountered include amalgamated distributary channel bars and related interdistributary bays. The distributary channels are thicker in the upper delta plain unit owing to a higher degree of stacking. Furthermore, sandstone thickness decreases in a southwest-northwest sense which indicates the direction of regression. This can be documented also with petrophysical characteristics of the reservoir reflected as a continuous decrease in porosity from 25 to 18%.

Gustavo, F.B.; Gonzales, C. (INTEVEP, S.A., Caracas (Venezuela))

1991-03-01T23:59:59.000Z

131

Training Hybrid Neuro-Fuzzy System to Infer Permeability in Wells on Maracaibo Lake, Venezuela  

E-Print Network [OSTI]

The high accuracy on inferrring of rocks properties, such as permeability ($k$), is a very useful study in the analysis of wells. This has led to development and use of empirical equations like Tixier, Timur, among others. In order to improve the inference of permeability we used a hybrid Neuro-Fuzzy System (NFS). The NFS allowed us to infer permeability of well, from data of porosity ($\\phi$) and water saturation ($Sw$). The work was performed with data from wells VCL-1021 (P21) and VCL-950 (P50), Block III, Maracaibo Lake, Venezuela. We evaluated the NFS equations ($k_{P50,i}(\\phi_i,Sw_i)$) with neighboring well data ($P21$), in order to verify the validity of the equations in the area. We have used ANFIS in MatLab.

Hurtado, Nuri; Torres, Julio

2014-01-01T23:59:59.000Z

132

Involvement of a chromatin modifier in response to mono-(2-ethylhexyl) phthalate (MEHP)-induced Sertoli cell injury: Probably an indirect action via the regulation of NF?B/FasL circuitry  

SciTech Connect (OSTI)

Highlights: •MTA1 expression is upregulated in SCs upon MEHP treatment. •Knockdown of MTA1 in SCs impairs the MEHP-induced NF?B signaling activation. •Knockdown of MTA1 inhibits recruitment of NF?B onto FasL promoter in MEHP-treated SCs. -- Abstract: The Fas/FasL signaling pathway, controlled by nuclear factor-?B (NF?B) at the transcriptional level, is critical for triggering germ cell apoptosis in response to mono-(2-ethylhexyl) phthalate (MEHP)-induced Sertoli cell (SC) injury, but the exact regulation mechanism remain unknown. Here, we discovered that expression level of Metastasis associated protein 1 (MTA1), a component of the Mi-2/nucleosome remodeling and deacetylase complex, was upregulated in SCs during the early recovery after MEHP exposure. This expression change was in line with the dynamic changes in germ cell apoptosis in response to MEHP treatment. Furthermore, a knockdown of MTA1 by RNAi in SCs was found to impair the MEHP-induced early activation of NF?B pathway and abolish the recruitment of NF?B onto FasL promoter, which consequently diminished the MEHP-triggered FasL induction. Considering that Fas/FasL is a well characterized apoptosis initiating signaling during SCs injury, our results point to a potential “switch on” effect of MTA1, which may govern the activation of NF?B/FasL cascade in MEHP-insulted SCs. Overall, the MTA1/NF?B/FasL circuit may serve as an important defensive/repairing mechanism to help to control the germ cell quality after SCs injury.

Chen, Shiwei [Department of Urology, 174th Hospital of PLA, Fujian 361001 (China)] [Department of Urology, 174th Hospital of PLA, Fujian 361001 (China); Dong, Yushu [Department of Neurosurgery, 463rd Hospital of PLA, Shenyang 110042 (China)] [Department of Neurosurgery, 463rd Hospital of PLA, Shenyang 110042 (China); Xu, Chun; Jiang, Liming; Chen, Yongjie; Jiang, Cheng [Department of Urology, 174th Hospital of PLA, Fujian 361001 (China)] [Department of Urology, 174th Hospital of PLA, Fujian 361001 (China); Hou, Wugang, E-mail: gangwuhou@163.com [Department of Anesthesiology, Xijing Hospital, Fourth Military Medical University, Xi’an 710032 (China)] [Department of Anesthesiology, Xijing Hospital, Fourth Military Medical University, Xi’an 710032 (China); Li, Wei, E-mail: liweipepeyato@163.com [Department of Human Anatomy, Histology and Embryology, Fourth Military Medical University, Xi’an 710032 (China)] [Department of Human Anatomy, Histology and Embryology, Fourth Military Medical University, Xi’an 710032 (China)

2013-11-01T23:59:59.000Z

133

Late Quaternary climate change from delta 13 O records of multiple species of planktonic foraminifera: High-resolution records from the Anoxic Cariaco Basin, Venezuela  

E-Print Network [OSTI]

252, 149-158. , 1954. waters of eastern Venezuela, Bol.C. Urey, Revised carbonate-water isotopic temperature scale,Atlantic-Mediterranean water H. -L. Lin, Institute of Marine

Lin, Hui-Ling; Peterson, Larry C; Overpeck, Jonathan T; Trumbore, Susan E; Murray, David W

1997-01-01T23:59:59.000Z

134

Settlement patterns in the eastern coast of Maracaibo Lake, Venezuela : evaluation of existing settlements and model for a low income sector of El Menito new town  

E-Print Network [OSTI]

This thesis is divided in two parts; The First part is the physical analysis of residential settlements in the Eastern Coast of Maracaibo Lake, Venezuela. The work is based on surveys, evaluations and comparisons of four ...

Rodriguez Navas, Humberto José

1983-01-01T23:59:59.000Z

135

The inhibitory effect of dexamethasone on platelet-derived growth factor-induced vascular smooth muscle cell migration through up-regulating PGC-1{alpha} expression  

SciTech Connect (OSTI)

Dexamethasone has been shown to inhibit vascular smooth muscle cell (VSMC) migration, which is required for preventing restenosis. However, the mechanism underlying effect of dexamethasone remains unknown. We have previously demonstrated that peroxisome proliferator-activated receptor gamma (PPAR{gamma}) coactivator-1 alpha (PGC-1{alpha}) can inhibit VSMC migration and proliferation. Here, we investigated the role of PGC-1{alpha} in dexamethasone-reduced VSMC migration and explored the possible mechanism. We first examined PGC-1{alpha} expression in cultured rat aortic VSMCs. The results revealed that incubation of VSMCs with dexamethasone could significantly elevate PGC-1{alpha} mRNA expression. In contrast, platelet-derived growth factor (PDGF) decreased PGC-1{alpha} expression while stimulating VSMC migration. Mechanistic study showed that suppression of PGC-1{alpha} by small interfering RNA strongly abrogated the inhibitory effect of dexamethasone on VSMC migration, whereas overexpression of PGC-1{alpha} had the opposite effect. Furthermore, an analysis of MAPK signal pathways showed that dexamethasone inhibited ERK and p38 MAPK phosphorylation in VSMCs. Overexpression of PGC-1{alpha} decreased both basal and PDGF-induced p38 MAPK phosphorylation, but it had no effect on ERK phosphorylation. Finally, inhibition of PPAR{gamma} activation by a PPAR{gamma} antagonist GW9662 abolished the suppressive effects of PGC-1{alpha} on p38 MAPK phosphorylation and VSMC migration. These effects of PGC-1{alpha} were enhanced by a PPAR{gamma} agonist troglitazone. Collectively, our data indicated for the first time that one of the anti-migrated mechanisms of dexamethasone is due to the induction of PGC-1{alpha} expression. PGC-1{alpha} suppresses PDGF-induced VSMC migration through PPAR{gamma} coactivation and, consequently, p38 MAPK inhibition.

Xu, Wei [Jiangsu Diabetes Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing 210093 (China) [Jiangsu Diabetes Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing 210093 (China); Department of cardiology, the Second Affiliated Hospital of Harbin Medical University, 246 Xuefu Road, Harbin 150081 (China); Guo, Ting; Zhang, Yan; Jiang, Xiaohong; Zhang, Yongxian [Jiangsu Diabetes Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing 210093 (China)] [Jiangsu Diabetes Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing 210093 (China); Zen, Ke, E-mail: kzen@nju.edu.cn [Jiangsu Diabetes Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing 210093 (China)] [Jiangsu Diabetes Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing 210093 (China); Yu, Bo, E-mail: yubodr@163.com [Department of cardiology, the Second Affiliated Hospital of Harbin Medical University, 246 Xuefu Road, Harbin 150081 (China)] [Department of cardiology, the Second Affiliated Hospital of Harbin Medical University, 246 Xuefu Road, Harbin 150081 (China); Zhang, Chen-Yu, E-mail: cyzhang@nju.edu.cn [Jiangsu Diabetes Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing 210093 (China)] [Jiangsu Diabetes Center, State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 22 Hankou Road, Nanjing 210093 (China)

2011-05-01T23:59:59.000Z

136

Alternative Regulation (Vermont)  

Broader source: Energy.gov [DOE]

Utility regulators, including the Public Service Board, have applied a new type of regulation, often called "alternative regulation" or "incentive regulation." There are many variants of this type...

137

Government Regulation  

E-Print Network [OSTI]

Abstract. Interest in the use of so-called voluntary approaches to supplement or replace formal environmental regulation is on the rise, both in Europe and in the United States. These approaches fall into two general ...

Ashford, Nicholas

2005-01-01T23:59:59.000Z

138

Mathis, J. T. et al., (2012). Storm-induced upwelling of high pCO2 waters onto the continental shelf of the western Arctic Ocean and implications for carbonate mineral saturation states. Geophysical  

E-Print Network [OSTI]

Mathis, J. T. et al., (2012). Storm-induced upwelling of high pCO2 waters onto the continental. Zhao, and G. Vargo (2011). Did the northeastern Gulf of Mexico become greener after the Deepwater-driven sediment transport on sediment accumulation in the Cariaco Basin, Venezuela. Marine Geology. Muhling, B

Meyers, Steven D.

139

Three-Dimensional Reconstruction of Tarantula Myosin Filaments Suggests How Phosphorylation May Regulate  

E-Print Network [OSTI]

, Instituto Venezolano de Investigaciones Científicas, Apdo. 20632, Caracas 1020A, Venezuela 2 University

Wriggers, Willy

140

Uptake of donor lymphocytes treated with 8-methoxypsoralen and ultraviolet A light by recipient dendritic cells induces CD4{sup +}CD25{sup +}Foxp3{sup +} regulatory T cells and down-regulates cardiac allograft rejection  

SciTech Connect (OSTI)

Extracorporeal photopheresis (ECP) is an effective immunomodulatory therapy and has been demonstrated to be beneficial for graft-vs-host disease and solid-organ allograft rejection. ECP involves reinfusion of a patient's autologous peripheral blood leukocytes treated ex vivo with 8-methoxypsoralen and UVA light radiation (PUVA). Previous studies focused only on ECP treatment of recipient immune cells. Our study is the first to extend the target of ECP treatment to donor immune cells. The results of in vitro co-culture experiments demonstrate uptake of donor PUVA-treated splenic lymphocytes (PUVA-SPs) by recipient immature dendritic cells (DCs). Phagocytosis of donor PUVA-SPs does not stimulate phenotype maturation of recipient DCs. In the same co-culture system, donor PUVA-SPs enhanced production of interleukin-10 and interferon-{gamma} by recipient DCs and impaired the subsequent capability of recipient DCs to stimulate recipient naive T cells. Phagocytosis of donor PUVA-SP (PUVA-SP DCs) by recipient DCs shifted T-cell responses in favor of T helper 2 cells. Infusion of PUVA-SP DCs inhibited cardiac allograft rejection in an antigen-specific manner and induced CD4{sup +}CD25{sup high}Foxp3{sup +} regulatory T cells. In conclusion, PUVA-SP DCs simultaneously deliver the donor antigen and the regulatory signal to the transplant recipient, and thus can be used to develop a novel DC vaccine for negative immune regulation and immune tolerance induction.

Zheng, De-Hua [Organ Transplant Center, Chinese PLA 309th Hospital, No. 17A Hei-Shan-Hu Road, Beijing 100091 (China)] [Organ Transplant Center, Chinese PLA 309th Hospital, No. 17A Hei-Shan-Hu Road, Beijing 100091 (China); Dou, Li-Ping [Department of Hematology, Chinese PLA General Hospital, No. 28 Fu-Xing Road, Beijing 100853 (China)] [Department of Hematology, Chinese PLA General Hospital, No. 28 Fu-Xing Road, Beijing 100853 (China); Wei, Yu-Xiang; Du, Guo-Sheng; Zou, Yi-Ping; Song, Ji-Yong; Zhu, Zhi-Dong; Cai, Ming; Qian, Ye-Yong [Organ Transplant Center, Chinese PLA 309th Hospital, No. 17A Hei-Shan-Hu Road, Beijing 100091 (China)] [Organ Transplant Center, Chinese PLA 309th Hospital, No. 17A Hei-Shan-Hu Road, Beijing 100091 (China); Shi, Bing-Yi, E-mail: shibingyi@medmail.com.cn [Organ Transplant Center, Chinese PLA 309th Hospital, No. 17A Hei-Shan-Hu Road, Beijing 100091 (China)] [Organ Transplant Center, Chinese PLA 309th Hospital, No. 17A Hei-Shan-Hu Road, Beijing 100091 (China)

2010-05-14T23:59:59.000Z

Note: This page contains sample records for the topic "venezuela regulation induced" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
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141

Nuclear apoJ: A low dose radiation inducible regulator of cell death. Final report for period September 15, 1998 - September 14, 2001  

SciTech Connect (OSTI)

This project was based on preliminary data that was published by Dr. Boothman (Yang et al. 2000) which indicated a strong induction of apoJ gene expression, increased secretion of the protein, and accumulation of an apparently somewhat different form of the apoJ protein in the nucleus of MCF-7 breast carcinoma cells undergoing response to DNA damage. A clone expressing apoJ protein was isolated that was capable of interacting with Ku80, a component of the double strand break repair complex that is essential for the successful repair of rearranging immunoglobulin and T-cell receptor genes as evidenced by failure to produce mature B and T cells in the absence of Ku70. ApoJ clones isolated and characterized by Dr. Boothman bound strongly to a Ku-70 ''bait'' protein. Over-expression of these same clones in a cell line was capable of killing the cell. ApoJ is very strongly induced in many instances of programmed cell death and has been proposed repeatedly to play some sort of effector role in the process. Our principle hypothesis for this study was that the strong induction of the apoJ gene and the particular expression of a nuclear form of the protein was potentially a causal factor in the decision point made by the cell as it attempts to repair double-strand breakage based DNA damage. The hypothesis was that if sufficiently high damage occurred, it would be deleterious to maintain the cell's viability through continued DNA repair. One method to inhibit DNA repair might be by inhibiting proteins such as Ku-70 that are necessary for double-strand break repair. If apoJ does play a critical role in tipping the decision balance over to cell death, we reasoned that deficiency of apoJ would cause increased accumulation of cells with DNA damage and that this might decrease cell death in response to DNA damage and increase tumor occurrence rates. To test this hypothesis and its potential implications, we exposed wildtype and apoJ deficient animals that we constructed through gene targeting to increasing levels of ionizing radiation from a Cesium source. Data gathered under the support of this grant application initially indicated that apoJ deficient animals were more resistant to radiation, but as we accumulated more and more data points and covered a tighter exposure range, the genotype-based differences became insignificant. However, the possibility existed that because mortality based radiation-resistance could be attributable to mechanism for which nuclear apoJ was not rate determining, we maintained a very large of colony of apoJ knockout and wildtype animals in both the C57/B16 and Cv129 strain backgrounds that were exposed to sub-lethal levels of ionizing radiation to monitor for the occurrence of tumors. These animals were allowed to fully recover and age normally in either germ free or normal animal housing. Our results demonstrated no significant differences between wildtype and apoJ knockout animals over a period that extended up to 30 months for individual animals. We recorded similar weight gain, a relatively low mortality rate, and a similar mixture and rate of sarcoma and adenocarcinomas after surviving the initial ionizing radiation exposures. Thus we conclude that apoJ gene function, which was totally eliminated by our gene targeting, did not influence radiation sensitivity or serve as a tumor suppressor in response to DNA damage.

Aronow, Bruce J.

2002-04-19T23:59:59.000Z

142

Diagenesis and reservoir characterization of the Block V-Lamar field, Maracaibo basin, Venezuela  

SciTech Connect (OSTI)

The Block V-Lamar field, located in the central portion of Maracaibo basin, Venezuela, is the subject of this study. The sedimentary section corresponds to a section of the Misoa Formation of early to middle Eocene age. These sediments were deposited in the upper delta plain as stacked distributary channel bars and associated facies and consist of relatively clean sandstones, fine to medium grained, with a sublitharenitic to subarkosic composition. The clay mineral assemblage is mainly composed of kaolinite, followed by chlorite and subordinate amounts of discrete smectite, discrete illite, and mixed-layer illite/smectite with order stratification with 20-30% of expandable layers, all of diagenetic origin. Even though there is a remnant of primary porosity reduced by silica cement, most porosity is secondary as a result of cement, matrix, and unstable grain dissolution. The petrographic XRD and SEM data obtained allow the authors to define the following paragenetic sequences: (1) mechanical compaction; (2) silica cementation; (3) patchy calcite cementation; (4) dissolution of matrix, cements, feldspars, and rock fragments; (5) kaolinite precipitation at or near feldspar intragranular pores; (6) matrix recrystallization to chlorite; (7) precipitation of second generation of kaolinite; and (8) precipitation of smectite. The porosity and permeability distribution in the reservoirs is the result of the net effect of the different diagenetic events that include early diagenesis, medium to late diagenesis, and telodiagenesis, mainly in response to basinwide tectonism.

Gonzales, C.; Gustavo, F. (INTEVEP, S.A., Caracas (Venezuela))

1991-03-01T23:59:59.000Z

143

Regulation 28: Library REGULATION 28: LIBRARY  

E-Print Network [OSTI]

Regulation 28: Library 180 REGULATION 28: LIBRARY The purpose of this Regulation is to safeguard the common interests of all Library users. All persons are admitted on the understanding that they have read and agreed to observe the Library Regulations. Breach of this Regulation could result in membership being

Sussex, University of

144

Universidad Simn Bolvar, Edif. Energtica, Planta Baja. Valle de Sartenejas, Baruta, Caracas, Edo. Miranda, Venezuela, 89000 Telef.: 58 212 906-3708 / 3709 / 3710 / 3711 Fax: 58 212 906-3712 www.ulab.usb.ve  

E-Print Network [OSTI]

. Miranda, Venezuela, 89000 Telef.: 58 212 906-3708 / 3709 / 3710 / 3711 Fax: 58 212 906-3712 www siguiente: Universidad Simón Bolívar Valle de Sartenejas Baruta; Edo. Miranda, 1080 Venezuela Cód. Doc.: UL

Vásquez, Carlos

145

E-Print Network 3.0 - apoptotic mechanisms induced Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

cells induced... Ab with nave apoptotic T cells induced robust immunity. The infusion of large numbers of apoptotic cells has... Regulation of Immune ... Source: Iowa...

146

Regulators, Requirements, Statutes  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Statutes Regulators, Requirements, Statutes The Laboratory must comply with environmental laws and regulations that apply to Laboratory operations. Contact Environmental...

147

Venezuela-MEM/USA-DOE Fossil Energy Report IV-11: Supporting technology for enhanced oil recovery - EOR thermal processes  

SciTech Connect (OSTI)

This report contains the results of efforts under the six tasks of the Tenth Amendment anti Extension of Annex IV, Enhanced Oil Recovery Thermal Processes of the Venezuela/USA Energy Agreement. This report is presented in sections (for each of the six Tasks) and each section contains one or more reports that were prepared to describe the results of the effort under each of the Tasks. A statement of each Task, taken from the Agreement Between Project Managers, is presented on the first page of each section. The Tasks are numbered 68 through 73. The first through tenth report on research performed under Annex IV Venezuela MEM/USA-DOE Fossil Energy Report Number IV-1, IV-2, IV-3, IV-4, IV-5, IV-6, IV-7, IV-8, IV-9, IV-10 contain the results of the first 67 Tasks. These reports are dated April 1983, August 1984, March 1986, July 1987, November 1988, December 1989, October 1991, February 1993, March 1995, and December 1997, respectively.

Venezuela

2000-04-06T23:59:59.000Z

148

Hypsilara royi gen. n. and sp. n. (Coleoptera, Elmidae, Larainae) from Southern Venezuela, with a revised key to Larainae of the Western Hemisphere  

E-Print Network [OSTI]

Here we describe a new genus, for a new species of riffle beetle, Hypsilara royi gen. n. and sp. n., from the tepui Cerro de la Neblina in southern Venezuela. This new genus can be distinguished from all other laraine genera by its small size (ca. 4...

Maier, Crystal A.; Spangler, Paul J.

2011-07-07T23:59:59.000Z

149

Forest Road Building Regulations  

Broader source: Energy.gov [DOE]

The Wisconsin Department of Natural Resources has regulations for building a forest road, if development requires one. Regulations include zoning ordinances and permits for stream crossing, grading...

150

Workshop in Regulation &  

E-Print Network [OSTI]

Electric Institute, "Regulatory Issues" Michael A. Crew, Rutgers University, "Incentive Regulation" Howard

Lin, Xiaodong

151

An investigation of the probability of occurrence of dry periods during the rainy season in the grassy highlands of Western Venezuela  

E-Print Network [OSTI]

. To him my deepest gratitude. To the Dean of the "Programa de Conservacion de Recursos Naturales Renovables, Universidad Nacional Experimental de los Llanos Dccidentales, Ezequiel Zamora, " Dr. R. Schargel, for his help, suggestions and ideas through...-1982. The data, daily precipita- tion values, were taken from five stations of the Ministerio del Ambiente y de los Recursos Naturales Renovables, Zona 8, Guanare, Venezuela (MARNR - monthly hydroclimatological bulletins) for the period 1960 to 1982. The five...

Quintana Gomez, Ramon Alfonso

1983-01-01T23:59:59.000Z

152

Natural Gas Regulations (Kentucky)  

Broader source: Energy.gov [DOE]

Kentucky Administrative Regulation title 805 promulgates the rules and regulations pertaining to natural gas production in Kentucky. In addition to KAR title 405, chapter 30, which pertains to any...

153

Approaches to identifying reservoir heterogeneity and reserve growth opportunities from subsurface data: The Oficina Formation, Budare field, Venezuela  

SciTech Connect (OSTI)

We applied an integrated geologic, geophysical, and engineering approach devised to identify heterogeneities in the subsurface that might lead to reserve growth opportunities in our analysis of the Oficina Formation at Budare field, Venezuela. The approach involves 4 key steps: (1) Determine geologic reservoir architecture; (2) Investigate trends in reservoir fluid flow; (3) Integrate fluid flow trends with reservoir architecture; and (4) Estimate original oil-in-place, residual oil saturation, and remaining mobile oil, to identify opportunities for reserve growth. There are three main oil-producing reservoirs in the Oficina Formation that were deposited in a bed-load fluvial system, an incised valley-fill, and a barrier-strandplain system. Reservoir continuity is complex because, in addition to lateral facies variability, the major Oficina depositional systems were internally subdivided by high-frequency stratigraphic surfaces. These surfaces define times of intermittent lacustrine and marine flooding events that punctuated the fluvial and marginal marine sedimentation, respectively. Syn and post depositional faulting further disrupted reservoir continuity. Trends in fluid flow established from initial fluid levels, response to recompletion workovers, and pressure depletion data demonstrated barriers to lateral and vertical fluid flow caused by a combination of reservoir facies pinchout, flooding shale markers, and the faults. Considerable reserve growth potential exists at Budare field because the reservoir units are highly compartment by the depositional heterogeneity and structural complexity. Numerous reserve growth opportunities were identified in attics updip of existing production, in untapped or incompletely drained compartments, and in field extensions.

Hamilton, D.S.; Raeuchle, S.K.; Holtz, M.H. [Bureau of Economic Geology, Austin, TX (United States)] [and others

1997-08-01T23:59:59.000Z

154

Venezuela-MEM/USA-DOE Fossil Energy Report XIII-1, Supporting Technology for Enhanced Oil Recovery, Microbial EOR  

SciTech Connect (OSTI)

The results from Annex XIII of the Cooperative Agreement between the United States Department of Energy (DOE) and the Ministry of Energy and Mines of the Republic of Venezuela (MEMV) have been documented and published with many researchers involved. Integrate comprehensive research programs in the area of Microbial Enhanced Oil Recovery (MEOR) ranged from feasibility laboratory studies to full-scale multi-well field pilots. The objective, to cooperate in a technical exchange of ideas and information was fully met throughout the life of the Annex. Information has been exchanged between the two countries through published reports and technical meetings between experts in both country's research communities. The meetings occurred every two years in locations coincident with the International MEOR conferences & workshops sponsored by DOE (June 1990, University of Oklahoma, September 1992, Brookhaven, September 1995, National Institute of Petroleum and Energy Research). Reports and publications produced during these years are listed in Appendix B. Several Annex managers have guided the exchange through the years. They included Luis Vierma, Jose Luis Zirritt, representing MEMV and E. B. Nuckols, Edith Allison, and Rhonda Lindsey, representing the U.S. DOE. Funding for this area of research remained steady for a few years but decreased in recent years. Because both countries have reduced research programs in this area, future exchanges on this topic will occur through ANNEX XV. Informal networks established between researchers through the years should continue to function between individuals in the two countries.

Ziritt, Jose Luis

1999-11-03T23:59:59.000Z

155

3 Library Regulations Definitions  

E-Print Network [OSTI]

3 Library Regulations Definitions In Regulation 3: 'Library' means the University Library as defined in Regulation 3.1; 'Library staff' means the staff of the University Library; 'Librarian' means the University Librarian and Head of Information Resources Directorate or nominee; `Library Committee' means

Mottram, Nigel

156

Computer Use Regulation Introduction  

E-Print Network [OSTI]

Computer Use Regulation #12;Introduction · The following training materials will reference the contents of the Computer Use Regulations, but should not serve as a substitute for reading the actual responsibilities NCSU employees have under the regulations. · North Carolina State University's computer networks

Liu, Paul

157

Load regulating expansion fixture  

DOE Patents [OSTI]

A free standing self contained device for bonding ultra thin metallic films, such as 0.001 inch beryllium foils is disclosed. The device will regulate to a predetermined load for solid state bonding when heated to a bonding temperature. The device includes a load regulating feature, whereby the expansion stresses generated for bonding are regulated and self adjusting. The load regulator comprises a pair of friction isolators with a plurality of annealed copper members located therebetween. The device, with the load regulator, will adjust to and maintain a stress level needed to successfully and economically complete a leak tight bond without damaging thin foils or other delicate components. 1 fig.

Wagner, L.M.; Strum, M.J.

1998-12-15T23:59:59.000Z

158

Load regulating expansion fixture  

DOE Patents [OSTI]

A free standing self contained device for bonding ultra thin metallic films, such as 0.001 inch beryllium foils. The device will regulate to a predetermined load for solid state bonding when heated to a bonding temperature. The device includes a load regulating feature, whereby the expansion stresses generated for bonding are regulated and self adjusting. The load regulator comprises a pair of friction isolators with a plurality of annealed copper members located therebetween. The device, with the load regulator, will adjust to and maintain a stress level needed to successfully and economically complete a leak tight bond without damaging thin foils or other delicate components.

Wagner, Lawrence M. (San Jose, CA); Strum, Michael J. (San Jose, CA)

1998-01-01T23:59:59.000Z

159

The inverted Lamar sub-basin, Lake Maracaibo, Venezuela: Tectonic evolution and hydrocarbon habitat  

SciTech Connect (OSTI)

In the central part of the Maracaibo basin, integration of recently acquired 3-D seismic and existing geological data has led to the definition of the Lamar sub-basin as an array of partially inverted half grabens which formed during Late Cretaceous and Early to Middle Eocene times as a result of transtensional episodes along older rift structures. This integration exercise has also led to the addition of new reserves in a mature oil province. Six major tectonic phases can be distinguished: (a.) Extension of the existing Paleozoic substrate during Jurassic rifting; (b.) Passive margin tectonic quiescence from Middle to Late Cretaceous; (c.) Paleocene uplift and erosion; (d.) Eocene transtension along reactivated Jurassic lineaments; (e.) Late Eocene to Mid Miocene inversion; (f.) Late Miocene to Recent post inversion and regional tilt. Distinctive tectonically induced unconformities within the Eocene sedimentary fill imply tectonic overprint rather than eustatic controls. The Eocene extensional structures were inverted in a selective manner depending upon their orientation relative to the dominant compressional vector. This in turn resulted in significant hydrocarbon re-migration and a rather complex fluid distribution throughout the area.

Arminio, J.F. [Maraven S.A., Caracas (Venezuela); Growcott, A.M. [Intera Information Technologies, Henley-Upon-Thames, Oxfordshire, (United Kingdom)

1996-08-01T23:59:59.000Z

160

Cenozoic oblique collision of South American and Caribbean plates: New evidence in the Coastal Cordillera of Venezuela and Trinidad  

SciTech Connect (OSTI)

The hinterland of the Caribbean Mts. orogen in Trinidad and Venezuela contains schist and gneiss whole protoliths are wholly or partly of continental provenance. The hinterland lies between the foreland thrust belt and terranes. The terranes are alien to continental South America (SA) and may have proto-Caribbean or Caribbean plate origins. The hinterland rocks were widely thought to come from sediments and granitoids of Mesozoic protolithic ages and to be of Cretaceous metamorphic age. Such rocks are now know to be of at least two or more types, as follows: (1) low grade, protoliths of pre-Mesozoic basement and shelfal cover of uncertain age range, inboard locus, Oligocene to mid-Miocene metamorphic ages younging eastward (Caracas, Paria, and Northern Range belts), and (2) higher grade including high P/T, varies protoliths of uncertain age range, Cretaceous and ( )early Paleogene metamorphic ages (Tacagua, Araya, Margarita). The geometry, protoliths, structures, and metamorphic ages of type 1 parautochthoneity and an origin as a thickened wedge of crust-cored passive margin cover. The wedge grew by accretion between about 35 and 20 Ma during oblique transport toward the foreland. The diachroneity of metamorphism implies, as does the timing of foreland deformation, that the wedge evolved in a right-oblique collision between northern SA and terranes moving wholly or partly with the Caribbean plate since the Eocene. Type 2 rocks probably came with the terranes and are products of convergent zone tectonics, either in the proto-Caribbean plate. The hinterland boundaries are brittle thrusts that are out of sequence and imply progressive contraction from mid-Cenozoic to the present.

Speed, R.C. (Northwestern Univ., Evanston, IL (United States)); Russo, R.M. (Carnegie Institute of Washington (United States)); Foland, K.A. (Ohio State Univ., Columbus (United States))

1993-02-01T23:59:59.000Z

Note: This page contains sample records for the topic "venezuela regulation induced" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


161

Pressure reducing regulator  

DOE Patents [OSTI]

A pressure reducing regulator that controls its downstream or outlet pressure to a fixed fraction of its upstream or inlet pressure. The regulator includes a housing which may be of a titanium alloy, within which is located a seal or gasket at the outlet end which may be made of annealed copper, a rod, and piston, each of which may be made of high density graphite. The regulator is insensitive to temperature by virtue of being without a spring or gas sealed behind a diaphragm, and provides a reference for a system in which it is being used. The rod and piston of the regulator are constructed, for example, to have a 1/20 ratio such that when the downstream pressure is less than 1/20 of the upstream pressure the regulator opens and when the downstream pressure exceeds 1/20 of the upstream pressure the regulator closes.

Whitehead, John C. (Davis, CA); Dilgard, Lemoyne W. (Willits, CA)

1995-01-01T23:59:59.000Z

162

Tidal Wetlands Regulations (Connecticut)  

Broader source: Energy.gov [DOE]

Most activities occurring in or near tidal wetlands are regulated, and this section contains information on such activities and required permit applications for proposed activities. Applications...

163

Regulation of natural monopolies  

E-Print Network [OSTI]

This chapter provides a comprehensive overview of the theoretical and empirical literature on the regulation of natural monopolies. It covers alternative definitions of natural monopoly, regulatory goals, alternative ...

Joskow, Paul L.

2005-01-01T23:59:59.000Z

164

Regulations of Wells (Florida)  

Broader source: Energy.gov [DOE]

The Department of Environmental Protection regulates the construction, repair, and abandonment of wells, as well as the persons and businesses undertaking such practices. Governing boards of water...

165

Nuclear Regulation (Montana)  

Broader source: Energy.gov [DOE]

This statute establishes a regulatory program for sources of ionizing radiation, to be administered by the Montana Department of Health and Human Services. These regulations address permitting and...

166

Utility Regulation (Indiana)  

Broader source: Energy.gov [DOE]

The Indiana Utility Regulatory Commission enforces regulations in this legislation that apply to all individuals, corporations, companies, and partnerships that may own, operate, manage, or control...

167

Coal Mining Regulations (Kentucky)  

Broader source: Energy.gov [DOE]

Kentucky Administrative Regulation Title 405 chapters 1, 2, 3, 5, 7, 8, 10, 12, 16, 18 and 20 establish the laws governing coal mining in the state.

168

E-Print Network 3.0 - atp induced vasodilatation Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Search Powered by Explorit Topic List Advanced Search Sample search results for: atp induced vasodilatation Page: << < 1 2 3 4 5 > >> 1 Current concepts of the regulation...

169

alpha-related apoptosis-inducing ligand: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

c release channel MAC, mitochondrial apoptosis-induced channel CiteSeer Summary: Bcl-2 family proteins regulate apoptosis, in part, by controlling formation of the mitochondrial...

170

Workshop in Regulation &  

E-Print Network [OSTI]

Smart Grid and Regulatory Issues April 1, 2011 K&L Gates LLP, 1601 K Street, NW, Washington, DC Viable Regulation." Victor Glass, NECA, Comments January 14, 2011 Smart Grid and Regulatory Issues Location: Rutgers, The Brattle Group, "Smart Grid/Smart Regulation" John Caldwell, EEI, "Economic Efficiency and the Smart Grid

Lin, Xiaodong

171

California Energy Commission ADOPTED REGULATIONS  

E-Print Network [OSTI]

California Energy Commission ADOPTED REGULATIONS FEBRUARY 2013 CEC-400-2010-004-CMF NONRESIDENTIAL BUILDING ENERGY USE DISCLOSURE PROGRAM Proposed Regulations: California Code of Regulations, Title 20, Division 2, Chapter 4, Article 9, Sections 1680 1685 CALIFORNIA ENERGY COMMISSION Edmund

172

Sulfur Dioxide Regulations (Ohio)  

Broader source: Energy.gov [DOE]

This chapter of the law establishes that the Ohio Environmental Protection Agency provides sulfur dioxide emission limits for every county, as well as regulations for the emission, monitoring and...

173

Dam Safety Regulation (Mississippi)  

Broader source: Energy.gov [DOE]

The purpose of the Dam Safety Regulation is to ensure that all dams constructed in the state of Mississippi are permitted and thus do not potentially harm wildlife, water supplies and property. ...

174

Dam Safety Regulations (Connecticut)  

Broader source: Energy.gov [DOE]

All dams, except those owned by the U.S., are under the jurisdiction of these regulations. These dams will be classified by hazard rating, and may be subject to periodic inspections. The...

175

Underground Storage Tank Regulations  

Broader source: Energy.gov [DOE]

The Underground Storage Tank Regulations is relevant to all energy projects that will require the use and building of pipelines, underground storage of any sorts, and/or electrical equipment. The...

176

SB 4 Well Stimulation Treatment Regulations Text of Proposed Regulations  

E-Print Network [OSTI]

surveys; routine activities that do not affect the integrity of the well or the formation; the removal SB 4 Well Stimulation Treatment Regulations Text of Proposed Regulations Page 1 of 13 SB 4 WELL STIMULATION TREATMENT REGULATIONS TEXT OF PROPOSED REGULATIONS Added text is shown in underline

177

Price regulation for waste hauling franchises in California: an examination of how regulators regulate pricing and the effects of competition on regulated markets  

E-Print Network [OSTI]

and popular recent “incentive regulation” alternatives,if costs increase. Incentive regulation – most particularly

Seltzer, Steven A.

2011-01-01T23:59:59.000Z

178

Distinct promoters regulate tissue-specific and differential expression of kallikrein 6 in CNS demyelinating disease  

E-Print Network [OSTI]

, and therein is regulated by injury. In the case of CNS demyelinating disease, K6 expression in CNS occurs in a tissue- specific fashion and are differentially regulated in response to CNS injury. While the human peripheral tissue. In a murine model of human CNS demyelinating inflammatory disease induced by Theiler's pi

Blaber, Michael

179

The availability of purine nucleotides regulates natural competence by controlling translation of the competence  

E-Print Network [OSTI]

The availability of purine nucleotides regulates natural competence by controlling translation that the depletion of purine nucleotides under competence- inducing conditions activates the CRP-dependent competence-specific regulator Sxy. Depletion of extra- or intra-cellular purine nucleotides activates Sxy translation, while

Redfield, Rosemary J. "Rosie"

180

Cell cycle regulators in the control of Emilie Blanchet, Jean-Sbastien Annicotte, and Lluis Fajas*  

E-Print Network [OSTI]

in the regulation of glucose-induced insulin secretion. There is enough evidence to indicate that the CDK4-pRB-E2F1 cycle regulators in lipids and adipocytes metabolism Lipids metabolism not only consists on lipid synthesis and degradation, but also on lipid signaling, and fatty acid storage in adipose tissue

Paris-Sud XI, Université de

Note: This page contains sample records for the topic "venezuela regulation induced" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


181

Design of Optimal Regulators  

E-Print Network [OSTI]

Current research suggests the use of a liner quadratic performance index for optimal control of regulators in various applications. Some examples include correcting the trajectory of rocket and air vehicles, vibration suppression of flexible structures, and airplane stability. In all these cases, the focus is in suppressing/decreasing system deviations rapidly. However, if one compares the Linear Quadratic Regulator (LQR) solution with optimal solutions (minimum time), it is seen that the LQR solution is less than optimal in some cases indeed (3-6) times that obtained using a minimum time solution. Moreover, the LQR solution is sometimes unacceptable in practice due to the fact that values of control extend beyond admissible limits and thus the designer must choose coefficients in the linear quadratic form, which are unknown. The authors suggest methods which allow finding a quasi-optimal LQR solution with bounded control which is closed to the minimum time solution. They also remand the process of the minimum time decision. Keywords: Optimal regulator, minimum time controller, Linear Quadratic Regulator (LQR). -- This paper is declared a work of the U.S. Government and not subject to copyright protection in the USA. The manuscript is accepted as paper AIAA-2003-6638 by 2nd AIAA Unmanned Unlimited Systems, Technologies, and Operations-Aerospace, Land, and See Conference and Workshop - Exhibit, San Diego, California, USA, 15-18 Sep. 2003.

Alexander Bolonkin; Robert Sierakowski

2007-01-19T23:59:59.000Z

182

Oleic AcidDependent Modulation of NITRIC OXIDE ASSOCIATED1 Protein Levels Regulates Nitric  

E-Print Network [OSTI]

of Agriculture­Agricultural Research Service, Washington State University, Prosser, Washington 99350 acid, which induces anti-inflammatory effects (Denys et al., 2001). FAs also serve as alarm molecules also regulate salt, drought, and heavy metal tolerance as well as wounding-induced responses

Kachroo, Pradeep

183

CREB regulation of nucleus accumbens excitability mediates social isolationinduced behavioral deficits  

E-Print Network [OSTI]

CREB regulation of nucleus accumbens excitability mediates social isolation­induced behavioral, Rachael L Neve4, Don C Cooper1, Carlos A Bolan~os3, Michel Barrot5, Colleen A McClung1 & Eric J Nestler1 and reduced electrical excitability of NAcSh neurons, which was sufficient to induce anxiety- like behaviors

Kalueff, Allan V.

184

Interrelationship of Program Regulations and Financial Assistance Regulations  

Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

The purpose of this Order is to set forth the interrelationship between all program regulations which will result in assistance awards (Program Regulations) and the Department of Energy Assistance Regulations (DOE-AR, 10 CRF Part 600), including procedures for exceptions, deviations or waivers.

1980-04-24T23:59:59.000Z

185

Emotion Regulation JAMES J. GROSS  

E-Print Network [OSTI]

CHAPTER 31 ·Emotion Regulation JAMES J. GROSS Have you ever gotten so angry that you've done), and self-regulation (Mischel, Shoda, & Rodriguez, 1989). What is new are the theoretical and empiri cal

Gross, James J.

186

Hazardous Waste Management Regulations (Mississippi)  

Broader source: Energy.gov [DOE]

The Hazardous Waste Management Regulations follow the EPA's definitions and guidelines for the most part, which are listed in 40 CFR parts 260-282. In addition to these federal regulations the...

187

Corporate governance and banking regulation  

E-Print Network [OSTI]

The globalisation of banking markets has raised important issues regarding corporate governance regulation for banking institutions. This research paper addresses some of the major issues of corporate governance as it relates to banking regulation...

Alexander, Kern

188

Private Regulation of Consumer Arbitration  

E-Print Network [OSTI]

of the need for future legislative action should take into account the effectiveness of this private regulation. That said, we do not assert that private regulation alone - with no public regulatory backstop, such as through court oversight - suffices...

Drahozal, Christopher R.; Zyontz, Samantha

2012-01-01T23:59:59.000Z

189

Surface Coal Mining Regulations (Mississippi)  

Broader source: Energy.gov [DOE]

The Surface Coal Mining Regulations are a combination of permitting requirements and environmental regulations that limit how, where and when coal can be mined. It protects lands that are under...

190

Cogeneration and its regulations  

SciTech Connect (OSTI)

In the near term, regulators, utility managements, and legislators will grapple with numerous issues surrounding the development of cogeneration projects as sources of electric power. The Federal Energy Regulatory Commission predicts that 12,000 MW of new cogeneration plants will be constructed during the 1980s, and all 50 states are in the process of implementing new regulations pursuant to the Public Utility Regulatory Policies Act. The US utility system's overall fuel efficiency of 29% offers rich opportunities to conserve fuel, reduce costs, and decrease pollution via cogeneration. Policymakers should stop viewing utilities simply as efficiency tax collectors on the one hand and opponents of innovation on the other. In addition to mothballing inefficient central utility stations, the US must rapidly deploy district heating with cogenerated heat; policymakers should look beyond the obsolete stream systems and encourage development of the high-temperature hot-water systems so successful in Europe.

Casten, T.R.; Ross, H.E.

1981-03-26T23:59:59.000Z

191

Regulation of Meiotic Recombination  

SciTech Connect (OSTI)

Meiotic recombination results in the heritable rearrangement of DNA, primarily through reciprocal exchange between homologous chromosome or gene conversion. In plants these events are critical for ensuring proper chromosome segregation, facilitating DNA repair and providing a basis for genetic diversity. Understanding this fundamental biological mechanism will directly facilitate trait mapping, conventional plant breeding, and development of genetic engineering techniques that will help support the responsible production and conversion of renewable resources for fuels, chemicals, and the conservation of energy (1-3). Substantial progress has been made in understanding the basal recombination machinery, much of which is conserved in organisms as diverse as yeast, plants and mammals (4, 5). Significantly less is known about the factors that regulate how often and where that basal machinery acts on higher eukaryotic chromosomes. One important mechanism for regulating the frequency and distribution of meiotic recombination is crossover interference - or the ability of one recombination event to influence nearby events. The MUS81 gene is thought to play an important role in regulating the influence of interference on crossing over. The immediate goals of this project are to use reverse genetics to identify mutants in two putative MUS81 homologs in the model plant Arabidopsis thaliana, characterize those mutants and initiate a novel forward genetic screen for additional regulators of meiotic recombination. The long-term goal of the project is to understand how meiotic recombination is regulated in higher eukaryotes with an emphasis on the molecular basis of crossover interference. The ability to monitor recombination in all four meiotic products (tetrad analysis) has been a powerful tool in the arsenal of yeast geneticists. Previously, the qrt mutant of Arabidopsis, which causes the four pollen products of male meiosis to remain attached, was developed as a facile system for assaying recombination using tetrad analysis in a higher eukaryotic system (6). This system enabled the measurement of the frequency and distribution of recombination events at a genome wide level in wild type Arabidopsis (7), construction of genetic linkage maps which include positions for each centromere (8), and modeling of the strength and pattern of interference (9). This proposal extends the use of tetrad analysis in Arabidopsis by using it as the basis for assessing the phenotypes of mutants in genes important for recombination and the regulation of crossover interference and performing a novel genetic screen. In addition to broadening our knowledge of a classic genetic problem - the regulation of recombination by crossover interference - this proposal also provides broader impact by: generating pedagogical tools for use in hands-on classroom experience with genetics, building interdisciplinary collegial partnerships, and creating a platform for participation by junior scientists from underrepresented groups. There are three specific aims: (1) Isolate mutants in Arabidopsis MUS81 homologs using T-DNA and TILLING (2) Characterize recombination levels and interference in mus81 mutants (3) Execute a novel genetic screen, based on tetrad analysis, for genes that regulate meiotic recombination

Gregory p. Copenhaver

2011-11-09T23:59:59.000Z

192

Improving CS regulations.  

SciTech Connect (OSTI)

President Carter issued Executive Order 12044 (3/28/78) that required all Federal agencies to distinguish between significant and insignificant regulations, and to determine whether a regulation will result in major impacts. This study gathered information on the impact of the order and the guidelines on the Office of Conservation and Solar Energy (CS) regulatory practices, investigated problems encountered by the CS staff when implementing the order and guidelines, and recommended solutions to resolve these problems. Major tasks accomplished and discussed are: (1) legislation, Executive Orders, and DOE Memoranda concerning Federal administrative procedures relevant to the development and analysis of regulations within CS reviewed; (2) relevant DOE Orders and Memoranda analyzed and key DOE and CS staff interviewed in order to accurately describe the current CS regulatory process; (3) DOE staff from the Office of the General Counsel, the Office of Policy and Evaluation, the Office of the Environment, and the Office of the Secretary interviewed to explore issues and problems encountered with current CS regulatory practices; (4) the regulatory processes at five other Federal agencies reviewed in order to see how other agencies have approached the regulatory process, dealt with specific regulatory problems, and responded to the Executive Order; and (5) based on the results of the preceding four tasks, recommendations for potential solutions to the CS regulatory problems developed. (MCW)

Nesse, R.J.; Scheer, R.M.; Marasco, A.L.; Furey, R.

1980-10-01T23:59:59.000Z

193

Self-regulating valve  

DOE Patents [OSTI]

A variable, self-regulating valve having a hydraulic loss coefficient proportional to a positive exponential power of the flow rate. The device includes two objects in a flow channel and structure which assures that the distance between the two objects is an increasing function of the flow rate. The range of spacing between the objects is such that the hydraulic resistance of the valve is an increasing function of the distance between the two objects so that the desired hydraulic loss coefficient as a function of flow rate is obtained without variation in the flow area.

Humphreys, D.A.

1982-07-20T23:59:59.000Z

194

WIPP Documents - Federal Regulations  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary)morphinanInformation Desert SouthwestTechnologies | Blandine Jerome VelenciaNewsNewsFederal Regulations 40 CFR

195

CO{sub 2} emissions from developing countries: Better understanding the role of Energy in the long term. Volume 2, Argentina, Brazil, Mexico, and Venezuela  

SciTech Connect (OSTI)

Recent years have witnessed a growing recognition of the link between emissions of carbon dioxide (CO{sub 2}) and changes in the global climate. Of all anthropogenic activities, energy production and use generate the single largest portion of these greenhouse gases. Although developing countries currently account for a small share of global carbon emissions, their contribution is increasing rapidly. Due to the rapid expansion of energy demand in these nations, the developing world`s share in global modern energy use rose from 16 to 27 percent between 1970 and 1990. If the growth rates observed over the past 20 years persist energy demand in developing will surpass that in the countries of the Organization for Economic Cooperation and Development (OECD) early in the 21st century. The study seeks to examine the forces that galvanize the growth of energy use and carbon emissions, to assess the likely future levels of energy and CO{sub 2} in selected developing nations and to identify opportunities for restraining this growth. The purpose of this report is to provide the quantitative information needed to develop effective policy options, not to identify the options themselves. These individual studies were conducted fro Argentina, Brazil, Mexico and Venezuela in Latin America.

Ketoff, A.; Sathaye, J.; Goldman, N. [eds.

1991-07-01T23:59:59.000Z

196

Nebraska Hazardous Waste Regulations (Nebraska)  

Broader source: Energy.gov [DOE]

These regulations, promulgated by the Department of Environmental Quality, contain provisions pertaining to hazardous waste management, waste standards, permitting requirements, and land disposal...

197

Nebraska Air Quality Regulations (Nebraska)  

Broader source: Energy.gov [DOE]

These regulations, promulgated by the Department of Environmental Quality, contain provisions pertaining to ambient air quality standards, pollution source operating permits, emissions reporting,...

198

Regulations For Gas Companies (Tennessee)  

Broader source: Energy.gov [DOE]

The Regulations for Gas Companies, implemented by the Tennessee Regulatory Authority (Authority) outline the standards for metering, distribution and electricity generation for utilities using gas....

199

Environmental Regulation, Globalization, and Innovation  

E-Print Network [OSTI]

This essay explores the complex relationship between environmental regulation, innovation, and sustainable development within the context of an increasingly globalizing economy. It will be argued that industrial policy, ...

Ashford, Nicholas

2009-01-01T23:59:59.000Z

200

Underground Injection Control Regulations (Kansas)  

Broader source: Energy.gov [DOE]

This article prohibits injection of hazardous or radioactive wastes into or above an underground source of drinking water, establishes permit conditions and states regulations for design,...

Note: This page contains sample records for the topic "venezuela regulation induced" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


201

TABLE OF CONTENTS CALIFORNIA CODE OF REGULATIONS ADMINISTRATIVE REGULATIONS  

E-Print Network [OSTI]

#12;#12;i TABLE OF CONTENTS CALIFORNIA CODE OF REGULATIONS ADMINISTRATIVE REGULATIONS Section 10............................................. Admin-7 Section 10-106 -- Locally Adopted Energy Standards Product U-Values, Solar Heat Gain Coefficient, and Air Leakage....... Admin-12 Section 10-112 -- Criteria

202

Regulating competitive markets: How to proceed?  

SciTech Connect (OSTI)

This paper describes the regulation of electricity and natural gas market. The prerequisites for market-based rates, regulating potentially competitive markets, regulating services where market power exists, and electronic communications and trading systems are discussed.

Santa, D.F. Jr.

1995-12-31T23:59:59.000Z

203

Post regulation circuit with energy storage  

DOE Patents [OSTI]

A charge regulation circuit provides regulation of an unregulated voltage supply and provides energy storage. The charge regulation circuit according to the present invention provides energy storage without unnecessary dissipation of energy through a resistor as in prior art approaches.

Ball, Don G. (Livermore, CA); Birx, Daniel L. (Oakley, CA); Cook, Edward G. (Livermore, CA)

1992-01-01T23:59:59.000Z

204

Vermont Hazardous Waste Management Regulations (Vermont)  

Broader source: Energy.gov [DOE]

These regulations are intended to protect public health and the environment by comprehensively regulating the generation, storage, collection, transport, treatment, disposal, use, reuse, and...

205

Aquifer Protection Area Land Use Regulations (Connecticut)  

Broader source: Energy.gov [DOE]

These regulations describe allowable activities within aquifer protection areas, the procedure by which such areas are delineated, and relevant permit requirements. The regulations also describe...

206

Price regulation for waste hauling franchises in California: an examination of how regulators regulate pricing and the effects of competition on regulated markets  

E-Print Network [OSTI]

Thomadakis, Stavros. “Price Regulation Under Uncertainty in698. Bös, Dieter. Pricing and Price Regulation. Elsevier.Optimal Structure of Public Prices. ” The American Economic

Seltzer, Steven A.

2011-01-01T23:59:59.000Z

207

International Electricity Regulation | Department of Energy  

Office of Environmental Management (EM)

Regulation International Electricity Regulation U.S. trade in electric energy with Canada and Mexico is rising, bringing economic and reliability benefits to the United States and...

208

Virginia Electric Utility Regulation Act (Virginia)  

Broader source: Energy.gov [DOE]

The Virginia Electric Utility Regulation Act constitutes the main legislation in Virginia that pertains to the regulation of the state's electric utilities. The Act directs the State Corporation...

209

Kansas Air Quality Regulations (Kansas)  

Broader source: Energy.gov [DOE]

All new air contaminant emission sources or alterations to emission sources that are required to be reported shall be in compliance with all applicable emission control regulations at the time that...

210

Water Quality Regulations (Rhode Island)  

Broader source: Energy.gov [DOE]

The purpose of these regulations is to establish water quality standards for the state's surface waters. These standards are intended to restore, preserve and enhance the physical, chemical and...

211

Ground Water Management Regulations (Louisiana)  

Broader source: Energy.gov [DOE]

The rules and regulations apply to the management of the state's ground water resources. In addition, the Commissioner of Conservation has recommended that oil and gas operators with an interest...

212

Modellering og regulering af affaldsforbrnding  

E-Print Network [OSTI]

deals with the regulation of a Danish waste incineration plant. It is tested if the flame front can on the Waste Incineration Plant, Haderslev Kraftvar- meværk in Denmark. Concurrently the position of the flame

213

State Water Permit Regulation (Arkansas)  

Broader source: Energy.gov [DOE]

It is the purpose of this regulation to adopt standards applicable to the storage, discharge, or disposal of any waste which, if unregulated, will cause pollution of waters of the state or result...

214

Mechanical regulation of signaling pathways in bone, William R. Thompson a,  

E-Print Network [OSTI]

Review Mechanical regulation of signaling pathways in bone, William R. Thompson a, , Clinton T A wide range of cell types depend on mechanically induced signals to enable appropriate physiological re- sponses. The skeleton is particularly dependent on mechanical information to guide the resident cell

215

Cavitation-resistant inducer  

DOE Patents [OSTI]

An improvement in an inducer for a pump wherein the inducer includes a hub, a plurality of radially extending substantially helical blades and a wall member extending about and encompassing an outer periphery of the blades. The improvement comprises forming adjacent pairs of blades and the hub to provide a substantially rectangular cross-sectional flow area which cross-sectional flow area decreases from the inlet end of the inducer to a discharge end of the inducer, resulting in increased inducer efficiency improved suction performance, reduced susceptibility to cavitation, reduced susceptibility to hub separation and reduced fabrication costs.

Dunn, Charlton (Calabasas, CA); Subbaraman, Maria R. (Canoga Park, CA)

1989-01-01T23:59:59.000Z

216

Cavitation-resistant inducer  

DOE Patents [OSTI]

An improvement in an inducer for a pump is disclosed wherein the inducer includes a hub, a plurality of radially extending substantially helical blades and a wall member extending about and encompassing an outer periphery of the blades. The improvement comprises forming adjacent pairs of blades and the hub to provide a substantially rectangular cross-sectional flow area which cross-sectional flow area decreases from the inlet end of the inducer to a discharge end of the inducer, resulting in increased inducer efficiency improved suction performance, reduced susceptibility to cavitation, reduced susceptibility to hub separation and reduced fabrication costs. 11 figs.

Dunn, C.; Subbaraman, M.R.

1989-06-13T23:59:59.000Z

217

Implementation Regulations 3TU MSc Sustainable Energy Technology Delft, 2014-2015 THE IMPLEMENTATION REGULATIONS  

E-Print Network [OSTI]

Implementation Regulations 3TU MSc Sustainable Energy Technology ­ Delft, 2014-2015 THE IMPLEMENTATION REGULATIONS 2014 - 2015 3TU MASTER'S DEGREE PROGRAMME Sustainable Energy Technology - Delft (SET) DELFT UNIVERSITY OF TECHNOLOGY #12;Implementation Regulations MSc Sustainable Energy Technology SET

218

Advanced Workshop in Regulation and  

E-Print Network [OSTI]

Forces in Regulated Industries January 13, 2012 Smart Grid and Rates Location: Rutgers Business School 1 Business Case for the Smart Grid" Glenn George, Bates White Economic Consulting, 11:15am-11:50am "Smart "Smart Grid in Virginia" Lunch 12:15pm-1:15pm Sheldon Switzer, Baltimore Gas & Electric Company, 1:15pm-1

Lin, Xiaodong

219

Advanced Workshop in Regulation and  

E-Print Network [OSTI]

Forces in Regulated Industries January 14, 2010 Smart Grid and Regulatory Issues Rutgers University 1, "Utility DR in Deregulated Markets" 11:50-12:20 James Reitzes, The Brattle Group, "Smart Grid/Smart and the Smart Grid" 1:50 ­ 2:20 Howard Spinner, Virginia State Corporation Commission, "Smart Grid in Virginia

Lin, Xiaodong

220

REGULATION SCOPING Alternative and Renewable  

E-Print Network [OSTI]

guidelines, definitions, and other provisions necessary for the administration of the Program Assessment · Fuel and Vehicle Technology Definitions · Sustainability Goals · Revenue Streams · Measure Program Results · AntiBacksliding Guidelines (Regulations developed by the Air Resources Board [ARB

Note: This page contains sample records for the topic "venezuela regulation induced" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


221

REGULATIONS OF UNIVERSITY OF FLORIDA  

E-Print Network [OSTI]

REGULATIONS OF UNIVERSITY OF FLORIDA 6C1-3.0051 Lost or Abandoned Property. (1) For the purposes and Archer Road on the south, along with any other educational or residential facilities occupied as the date on which an identified owner of lost or abandoned property is notified by the Property Custodian

Pilyugin, Sergei S.

222

VMP1 related autophagy and apoptosis in colorectal cancer cells: VMP1 regulates cell death  

SciTech Connect (OSTI)

Highlights: •This research confirmed VMP1 as a regulator of autophagy in colorectal cancer cell lines. •We proved the pro-survival role of VMP1-mediated autophagy in colorectal cancer cell lines. •We found the interaction between VMP1 and BECLIN1 also existing in colorectal cancer cell lines. -- Abstract: Vacuole membrane protein 1 (VMP1) is an autophagy-related protein and identified as a key regulator of autophagy in recent years. In pancreatic cell lines, VMP1-dependent autophagy has been linked to positive regulation of apoptosis. However, there are no published reports on the role of VMP1 in autophagy and apoptosis in colorectal cancers. Therefore, to address this gap of knowledge, we decided to interrogate regulation of autophagy and apoptosis by VMP1. We have studied the induction of autophagy by starvation and rapamycin treatment in colorectal cell lines using electron microscopy, immunofluorescence, and immunoblotting. We found that starvation-induced autophagy correlated with an increase in VMP1 expression, that VMP1 interacted with BECLIN1, and that siRNA mediated down-regulation of VMP1-reduced autophagy. Next, we examined the relationship between VMP1-dependent autophagy and apoptosis and found that VMP1 down-regulation sensitizes cells to apoptosis and that agents that induce apoptosis down-regulate VMP1. In conclusion, similar to its reported role in other cell types, VMP1 is an important regulator of autophagy in colorectal cell lines. However, in contrast to its role in pancreatic cell lines, in colorectal cancer cells, VMP1-dependent autophagy appears to be pro-survival rather than pro-cell death.

Qian, Qinyi [Department of Ultrasonograph, Changshu No. 2 People’s Hospital, Changshu (China)] [Department of Ultrasonograph, Changshu No. 2 People’s Hospital, Changshu (China); Zhou, Hao; Chen, Yan [Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou (China)] [Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou (China); Shen, Chenglong [Department of General Surgery, Changshu No. 2 People’s Hospital, Changshu (China)] [Department of General Surgery, Changshu No. 2 People’s Hospital, Changshu (China); He, Songbing; Zhao, Hua; Wang, Liang [Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou (China)] [Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou (China); Wan, Daiwei, E-mail: 372710369@qq.com [Department of Hepatobiliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou (China)] [Department of Hepatobiliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou (China); Gu, Wen, E-mail: 505339704@qq.com [Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou (China)] [Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou (China)

2014-01-17T23:59:59.000Z

223

Radiation-induced angiosarcoma  

E-Print Network [OSTI]

1a Figure 1b Figure 1. Radiation-induced angiosarcoma in afollowing completion of radiation therapy. Figure 2a Figurecell histiocytosis after radiation for breast carcinoma: can

Anzalone, C Lane; Cohen, Philip R; Diwan, Abdul H; Prieto, Victor G

2013-01-01T23:59:59.000Z

224

Friction Induced Skin Tags  

E-Print Network [OSTI]

Duplantis KL, Jones BH. Friction blisters. Pathophysiology,Friction Induced Skin Tags Francisco Allegue MD 1 , Carmenetiopathogenic role for friction. Introduction Skin tags (

Allegue, Francisco; Fachal, Carmen; Pérez-Pérez, Lidia

2008-01-01T23:59:59.000Z

225

Of Refrigerators & Regulations | Department of Energy  

Broader source: Energy.gov (indexed) [DOE]

Regulations Of Refrigerators & Regulations February 8, 2011 - 9:29am Addthis Jesse Lee White House Director of Online Affairs Editor's Note: This entry has been cross-posted from...

226

Stream Flow Standards and Regulations (Connecticut)  

Broader source: Energy.gov [DOE]

These regulations apply to all rivers and streams in Connecticut. Dam owners need to comply with these regulations unless the dam is principally used for hydroelectric power generation and is under...

227

The Building Standard (Scotland) Amendment Regulations 1964   

E-Print Network [OSTI]

STATUTORY INSTRUMENTS 1964 No. 802 (S. 50) BUILDING AND BUILDINGS The Building Standards (Scotland) Amendment Regulations 1964...

Noble, Michael

1964-01-01T23:59:59.000Z

228

Solid Waste and Infectious Waste Regulations (Ohio)  

Broader source: Energy.gov [DOE]

This chapter of the law that establishes the Ohio Environmental Protection Agency establishes the rules and regulations regarding solid waste.

229

Natural gas cavern storage regulation  

SciTech Connect (OSTI)

Investigation of an incident at an LPG storage facility in Texas by U.S. Department of Transportation resulted in recommendation that state regulation of natural gas cavern storage might be improved. Interstate Oil & Gas Compact Commission has established a subcommittee to analyze the benefits and risks associated with natural gas cavern storage, and to draft a regulation model which will suggest engineering and performance specifications. The resulting analysis and regulatory language will be reviewed by I.O.G.C.C., and if approved, distributed to member states (including New York) for consideration. Should the states desire assistance in modifying the language to reflect local variables, such as policy and geology, I.O.G.C.C. may offer assistance. The proposed presentation will review the I.O.G.C.C. product (if published at that date), and discuss implications of its application in New York.

Heneman, H.

1995-09-01T23:59:59.000Z

230

NARUC: Regulation at the crossroads  

SciTech Connect (OSTI)

This article reports on the review of changes during the last decade of the regulation of industries by the federal government. The state commissioners that make up the National Association of Regulatory Utility Commissioners discuss the changing regulatory climate for a competitive industry, changes in the federal-state relationship, proposed changes in jurisdictional boundaries, acid rain legislation and emissions trading, and Senator J. Bennet Johnson's amendment to the Public Utilities Holding Company Act.

Not Available

1990-01-04T23:59:59.000Z

231

Frequency regulator for synchronous generators  

DOE Patents [OSTI]

The present invention is directed to a novel frequency regulator which controls a generator output frequency for variations in both the input power to the generator and the power supplied to an uncontrolled external load. The present invention further includes over current and current balance protection devices which are relatively inexpensive to manufacture, which may be encapsulated to provide protection from the operating environment and which respond more quickly than previously known electromechanical devices. 11 figs.

Karlicek, R.F.

1982-08-10T23:59:59.000Z

232

Regulation of Tidal and Wave Energy Projects (Maine)  

Broader source: Energy.gov [DOE]

State regulation of tidal and wave energy projects is covered under the Maine Waterway Development and Conservation Act (MWDCA), and complements regulation by the Federal Energy Regulation...

233

Reformulating Competition? Gasoline Content Regulation and Wholesale Gasoline Prices  

E-Print Network [OSTI]

Regulation and Arbitrage in Wholesale Gasoline Markets,Content Regulation and Wholesale Gasoline Prices JenniferCONTENT REGULATION AND WHOLESALE GASOLINE PRICES by Jennifer

Brown, Jennifer; Hastings, Justine; Mansur, Erin T.; Villas-Boas, Sofia B

2007-01-01T23:59:59.000Z

234

Advanced Clean Cars Zero Emission Vehicle Regulation  

E-Print Network [OSTI]

Advanced Clean Cars Zero Emission Vehicle Regulation ZEV #12;Advanced Clean Cars ZEV Program 2020 2021 2022 2023 2024 2025 Current Regulation -ZEVs Current Regulation -PHEVs Projected: PHEVs 15Net ­ Blueprint Plan ­ Regional clusters, environmental and economic analysis · Clean Fuels Outlet

California at Davis, University of

235

Regulation of Hydraulic Fracturing in California  

E-Print Network [OSTI]

APRIL 2013 Regulation of Hydraulic Fracturing in California: A WAsteWAteR And WAteR QuAlity Pe | Regulation of Hydraulic Fracturing in California Wheeler Institute for Water Law & Policy Center for Law #12;Regulation of Hydraulic Fracturing in California | 3Berkeley law | wheeler InstItute for water law

Kammen, Daniel M.

236

NRC - regulator of nuclear safety  

SciTech Connect (OSTI)

The U.S. Nuclear Regulatory Commission (NRC) was formed in 1975 to regulate the various commercial and institutional uses of nuclear energy, including nuclear power plants. The agency succeeded the Atomic Energy Commission, which previously had responsibility for both developing and regulating nuclear activities. Federal research and development work for all energy sources, as well as nuclear weapons production, is now conducted by the U.S. Department of Energy. Under its responsibility to protect public health and safety, the NRC has three principal regulatory functions: (1) establish standards and regulations, (2) issue licenses for nuclear facilities and users of nuclear materials, and (3) inspect facilities and users of nuclear materials to ensure compliance with the requirements. These regulatory functions relate to both nuclear power plants and to other uses of nuclear materials - like nuclear medicine programs at hospitals, academic activities at educational institutions, research work, and such industrial applications as gauges and testing equipment. The NRC places a high priority on keeping the public informed of its work. The agency recognizes the interest of citizens in what it does through such activities as maintaining public document rooms across the country and holding public hearings, public meetings in local areas, and discussions with individuals and organizations.

NONE

1997-05-01T23:59:59.000Z

237

Final Report for Regulation of Embryonic Development in Higher Plants  

SciTech Connect (OSTI)

The overall goal of the project was to define the cellular processes that underlie embryo development in plants at a mechanistic level. Our studies focused on a critical transcriptional regulator, Arabidopsis LEAFY COTYLEDON (LEC1), that is necessary and sufficient to induce processes required for embryo development. Because LEC1 regulates lipid accumulation during the maturation phase of embryo development, information about LEC1 may be useful in designing approaches to enhance biofuel production in plants. During the tenure of this project, we determined the molecular mechanisms by which LEC1 acts as a transcription factor in embryos. We also identified genes directly regulated by LEC1 and showed that many of these genes are involved in maturation processes. This information has been useful in dissecting the gene regulatory networks controlling embryo development. Finally, LEC1 is a novel isoform of a transcription factor that is conserved among eukaryotes, and LEC1 is active primarily in seeds. Therefore, we determined that the LEC1-type transcription factors first appeared in lycophytes during land plant evolution. Together, this study provides basic information that has implications for biofuel production.

Harada, John J. [University of California, Davis] [University of California, Davis

2013-10-22T23:59:59.000Z

238

Frequency Regulation Basics and Trends  

SciTech Connect (OSTI)

The electric power system must address two unique requirements: the need to maintain a near real-time balance between generation and load, and the need to adjust generation (or load) to manage power flows through individual transmission facilities. These requirements are not new: vertically integrated utilities have been meeting them for a century as a normal part of conducting business. With restructuring, however, the services needed to meet these requirements, now called ''ancillary services'', are being more clearly defined. Ancillary services are those functions performed by the equipment and people that generate, control, and transmit electricity in support of the basic services of generating capacity, energy supply, and power delivery. The Federal Energy Regulatory Commission (FERC) has defined such services as those ''necessary to support the transmission of electric power from seller to purchaser given the obligations of control areas and transmitting utilities within those control areas to maintain reliable operations of the interconnected transmission system''. This statement recognizes the importance of ancillary services for both bulk-power reliability and support of commercial transactions. Balancing generation and load instantaneously and continuously is difficult because loads and generators are constantly fluctuating. Minute-to-minute load variability results from the random turning on and off of millions of individual loads. Longer-term variability results from predictable factors such as the daily and seasonal load patterns as well as more random events like shifting weather patterns. Generators also introduce unexpected fluctuations because they do not follow their generation schedules exactly and they trip unexpectedly due to a range of equipment failures. The output from wind generators varies with the wind. Storage technologies should be ideal suppliers of several ancillary services, including regulation, contingency reserves (spinning reserve, supplemental reserve, replacement reserve), and voltage support. These services are not free; in regions with energy markets, generators are paid to supply these services. In vertically integrated utilities (without energy markets) the utility incurs significant costs to supply these services. Supplying these services may be a significant business opportunity for emerging storage technologies. This report briefly explores the various ancillary services that may be of interest to storage. It then focuses on regulation, the most expensive ancillary service. It also examines the impact that increasing amounts of wind generation may have on regulation requirements, decreasing conventional regulation supplies, and the implications for energy storage.

Kirby, BJ

2005-05-06T23:59:59.000Z

239

Systems analysis of multiple regulator perturbations allows discoveryo...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Systems analysis of multiple regulator perturbations allows discoveryof virulence factors in Salmonella. Systems analysis of multiple regulator perturbations allows discoveryof...

240

Endocrine regulation of placental phenotype  

E-Print Network [OSTI]

substrate uptake during increased ovine fetal cortisol concentration. 682 Am J Physiol 1996; 271:E186-E191. 683 102 Timmerman M, Teng C, Wilkening RB, Fennessey P, Battaglia FC, Meschia G. Effect of 684 dexamethasone on fetal hepatic glutamine... -glutamate exchange. Am J Physiol 2000; 685 278: E839-E845. 686 103 Barbera A, Wilkening RB, Teng C, Battaglia FC, Meschia G. Metabolic alterations in the 687 fetal hepatic and umbilical circulations during glucocorticoid-induced parturition in 688 sheep. Pediatr...

Fowden, A.L.; Forhead, A.J.; Sferruzzi-Perri, A.N.; Burton, G. J.; Vaughan, O.R.

2014-12-03T23:59:59.000Z

Note: This page contains sample records for the topic "venezuela regulation induced" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


241

Dynamic Voltage Regulation Using Distributed Energy Resources  

SciTech Connect (OSTI)

Many distributed energy resources (DE) are near load centres and equipped with power electronics converters to interface with the grid, therefore it is feasible for DE to provide ancillary services such as voltage regulation, nonactive power compensation, and power factor correction. A synchronous condenser and a microturbine with an inverter interface are implemented in parallel in a distribution system to regulate the local voltage. Voltage control schemes of the inverter and the synchronous condenser are developed. The experimental results show that both the inverter and the synchronous condenser can regulate the local voltage instantaneously, while the dynamic response of the inverter is faster than the synchronous condenser; and that integrated voltage regulation (multiple DE perform voltage regulation) can increase the voltage regulation capability, increase the lifetime of the equipment, and reduce the capital and operation costs.

Xu, Yan [ORNL; Rizy, D Tom [ORNL; Li, Fangxing [ORNL; Kueck, John D [ORNL

2007-01-01T23:59:59.000Z

242

The Arabidopsis blue light receptor cryptochrome 2 is a nuclear protein regulated by a blue light-dependent post-  

E-Print Network [OSTI]

The Arabidopsis blue light receptor cryptochrome 2 is a nuclear protein regulated by a blue light Charles E. Young Dr. South, Los Angeles, CA 90095-1606, USA Summary Cryptochrome 2 is a ¯avin-type blue light receptor mediating ¯oral induction in response to photoperiod and a blue light-induced hypocotyl

Lin, Chentao

243

Regulations for Air Quality (Quebec, Canada)  

Broader source: Energy.gov [DOE]

This Regulation establishes emission standards for particulates and gases, emission opacity standards, standards of air quality and control measures to prevent, eliminate or reduce the emission of...

244

Council on Environmental Quality - Regulations for Implementing...  

Open Energy Info (EERE)

OpenEI Reference LibraryAdd to library Legal Document- StatuteStatute: Council on Environmental Quality - Regulations for Implementing the Procedural Provisions of the NEPALegal...

245

Water Pollution Control Permit Regulations (Vermont)  

Broader source: Energy.gov [DOE]

These regulations outline the permits and permitting processes for point discharges to surface waters and outline the monitoring and reporting requirements.

246

Rhode Island Pretreatment Regulations (Rhode Island)  

Broader source: Energy.gov [DOE]

These regulations set standards for water pretreatment prior to release to Publicly Owned Treatment Works (POTWs), and require effluent data including the identity, amount, frequency, concentration...

247

Inland Wetlands and Water Courses Regulations (Connecticut)  

Broader source: Energy.gov [DOE]

Regulated activities in or near inland wetlands and water courses include the removal or depositing of material, land or water obstruction or alteration, construction, pollution, or water diversion...

248

Massachusetts Endangered Species Act Regulations (Massachusetts)  

Broader source: Energy.gov [DOE]

The regulations that accompany the Massachusetts Endangered Species Act list three categories of animals and plants in need of protection: endangered, threatened, and species of special concern....

249

Exporting licensing regulations affecting US geothermal firms  

SciTech Connect (OSTI)

This document presents a brief introduction and overview of the Department of Commerce's Export Administration Regulations which might affect potential US geothermal goods exporters. It is intended to make US geothermal firms officials aware of the existence of such regulations and to provide them with references, contacts and phone numbers where they can obtain specific and detailed information and assistance. It must be stressed however, that the ultimate responsibility for complying with the above mentioned regulations lies with the exporter who must consult the complete version of the regulations.

Not Available

1988-08-01T23:59:59.000Z

250

Gas and Electric Utilities Regulation (South Dakota)  

Broader source: Energy.gov [DOE]

This legislation contains provisions for gas and electric utilities. As part of these regulations, electric utilities are required to file with the Public Utilities Commission a document regarding...

251

Solid Waste Regulations (Nova Scotia, Canada)  

Broader source: Energy.gov [DOE]

Nova Scotia Environment administers waste management for the province. Regulations include specific rules and standards for landfills, establish a Resource Recovery Fund, and guidelines for...

252

Implementation Regulations MSc Chemical Engineering 2013-2014 THE IMPLEMENTATION REGULATIONS  

E-Print Network [OSTI]

.......................................................................................................4 Article 7 ­ The Nuclear Science & Engineering track. The programme comprises the following tracks: - Chemical Product Engineering, - Process Engineering, - NuclearImplementation Regulations MSc Chemical Engineering 2013-2014 THE IMPLEMENTATION REGULATIONS 2013

253

Chk2 regulates transcription-independent p53-mediated apoptosis in response to DNA damage  

SciTech Connect (OSTI)

The tumor suppressor protein p53 plays a central role in the induction of apoptosis in response to genotoxic stress. The protein kinase Chk2 is an important regulator of p53 function in mammalian cells exposed to ionizing radiation (IR). Cells derived from Chk2-deficient mice are resistant to the induction of apoptosis by IR, and this resistance has been thought to be a result of the defective transcriptional activation of p53 target genes. It was recently shown, however, that p53 itself and histone H1.2 translocate to mitochondria and thereby induces apoptosis in a transcription-independent manner in response to IR. We have now examined whether Chk2 also regulates the transcription-independent induction of apoptosis by p53 and histone H1.2. The reduced ability of IR to induce p53 stabilization in Chk2-deficient thymocytes was associated with a marked impairment of p53 and histone H1 translocation to mitochondria. These results suggest that Chk2 regulates the transcription-independent mechanism of p53-mediated apoptosis by inducing stabilization of p53 in response to IR.

Chen Chen [Department of Geriatric Research, National Institute for Longevity Sciences, National Center for Geriatrics and Gerontology, Obu, Aichi 474-8522 (Japan); Shimizu, Shigeomi [Department of Post-Genomics Diseases, Osaka University Medical School, Suita, Osaka 565-0871 (Japan); Tsujimoto, Yoshihide [Department of Post-Genomics Diseases, Osaka University Medical School, Suita, Osaka 565-0871 (Japan); Motoyama, Noboru [Department of Geriatric Research, National Institute for Longevity Sciences, National Center for Geriatrics and Gerontology, Obu, Aichi 474-8522 (Japan)]. E-mail: motoyama@nils.go.jp

2005-07-29T23:59:59.000Z

254

Use of geostatistic techniques to describe a reservoir to be submitted into a secondary recovery process field case: {open_quotes}Eocene B-Inferior/VLG-3659, Ceuta, Venezuela{close_quotes}  

SciTech Connect (OSTI)

This study presents the results of an integrated reservoir study of the Eocene B-Inferior/VLG-3659, Area 7, Ceuta filed. This field located in the Maracaibo Lake in the western side of Venezuela. The objective was to evaluating the feasibility to implement a secondary recovery project by means of water flooding. Core information was used for this study (194 ft), PVT analysis, RFI, build-up and statistic`s pressure analysis, modem logs and production history data. Using geostatistical techniques (Kriging) it was defined a low uncertainty geological model that was validated by means of a black oil simulator (Eclipse). The results showed a good comparison of historical pressure of the reservoir against those obtained from the model, without the need of {open_quotes}history matching{close_quotes}. It means without modifying neither the initial rock properties nor reservoir fluids. The results of this study recommended drilling in two new locations, also the reactivation of four producing wells and water flooding under peripherical array by means of four injection wells, with the recovery of an additional 30.2 MMSTB. The economical evaluation shows an internal return rate of 31.4%.

Hernandez, T.; Poquioma, W. [Maraven, S.A., Caracas (Venezuela)

1997-08-01T23:59:59.000Z

255

Regulation of phosphate starvation response in Arabidopsis  

E-Print Network [OSTI]

for the degree of MASTER OF SCIENCE December 2006 Major Subject: Biology REGULATION OF PHOSPHATE STARVATION RESPONSE IN ARABIDOPSIS A Thesis by BETH ELENE ARMSTRONG THOMAS Submitted... Alan Pepper Dorothy Shippen Head of Department, Vincent Cassone December 2006 Major Subject: Biology iii ABSTRACT Regulation of Phosphate Starvation Response...

Thomas, Beth Elene Armstrong

2007-04-25T23:59:59.000Z

256

Student Regulations and Procedures Academic Division  

E-Print Network [OSTI]

Student Regulations and Procedures Academic Division 2007/2008 3 RULES FOR STUDENT CONDUCT fees, award ceremonies and other matters www.mmu.ac.uk/academic/student_regulations.php #12;RULES of Governors in accordance with the following Articles of Government: 7.1.6 Subject to the responsibilities

257

Engineer Regulation 1110-2-1150  

E-Print Network [OSTI]

CECW-EP Engineer Regulation 1110-2-1150 Department of the Army U.S. Army Corps of Engineers Washington, DC 20314-1000 ER 1110-2-1150 31 August 1999 Engineering and Design ENGINEERING AND DESIGN 1110-2-1150 U.S. Army Corps of Engineers CECW-EP Washington, D.C. 20314-1000 Regulation No. 1110

US Army Corps of Engineers

258

Geometrically induced magnetic catalysis and critical dimensions  

E-Print Network [OSTI]

We discuss the combined effect of magnetic fields and geometry in interacting fermionic systems. At leading order in the heat-kernel expansion, the infrared singularity (that in flat space leads to the magnetic catalysis) is regulated by the chiral gap effect and the catalysis is deactivated by effect of the curvature. We discover that an infrared singularity may reappear from higher-order terms in the heat kernel expansion leading to a novel form of geometrically induced magnetic catalysis (absent in flat space). The dynamical mass squared is then modified not only due to the chiral gap effect by an amount proportional to the curvature, but also by a magnetic shift $\\propto (4-D)eB$ where $D$ represents the number of space-time dimensions. We argue that $D=4$ is a critical dimension across which the behaviour of the magnetic shift changes qualitatively.

Antonino Flachi; Kenji Fukushima; Vincenzo Vitagliano

2015-02-21T23:59:59.000Z

259

Geometrically induced magnetic catalysis and critical dimensions  

E-Print Network [OSTI]

We discuss the combined effect of magnetic fields and geometry in interacting fermionic systems. At leading order in the heat-kernel expansion, the infrared singularity (that in flat space leads to the magnetic catalysis) is regulated by the chiral gap effect and the catalysis is deactivated by effect of the curvature. We discover that an infrared singularity may reappear from higher-order terms in the heat kernel expansion leading to a novel form of geometrically induced magnetic catalysis (absent in flat space). The dynamical mass squared is then modified not only due to the chiral gap effect by an amount proportional to the curvature, but also by a magnetic shift $\\propto (4-D)eB$ where $D$ represents the number of space-time dimensions. We argue that $D=4$ is a critical dimension across which the behaviour of the magnetic shift changes qualitatively.

Flachi, Antonino; Vitagliano, Vincenzo

2015-01-01T23:59:59.000Z

260

NOTICE OF PROPOSED REGULATION AMENDMENT Date: November 8, 2011  

E-Print Network [OSTI]

REGULATION AMENDMENT: Dr. James Fenton, Director, Florida Solar Energy Center COMMENTS CONCERNING.: Solar Thermal PV Equipment Testing Standards UCF-8.007 SUMMARY OF REGULATION: This regulation-mail: regulations@mail.ucf.edu FULL TEXT OF THE PROPOSED REGULATION AMENDMENT: UCF-8.007 Solar Thermal PV Equipment

Richardson, Martin C.

Note: This page contains sample records for the topic "venezuela regulation induced" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


261

NOTICE OF REGULATION REPEAL Date: July 1, 2010  

E-Print Network [OSTI]

. James Fenton, Director, Florida Solar Energy Center COMMENTS CONCERNING THE REGULATION REPEAL SHOULDNOTICE OF REGULATION REPEAL Date: July 1, 2010 REGULATION TITLE: REGULATION NO.: Solar Thermal OF THE PROPOSED REGULATION REPEAL: UCF-8.002 Solar Thermal Collector and PV Module Testing Standards. (1

Wu, Shin-Tson

262

NOTICE OF PROPOSED REGULATION AMENDMENT Date: November 8, 2011  

E-Print Network [OSTI]

REGULATION AMENDMENT: Dr. James Fenton, Director, Florida Solar Energy Center COMMENTS CONCERNING.: Solar Thermal Collector and PV Module Certification UCF-8.008 SUMMARY OF REGULATION: This regulation-mail: regulations@mail.ucf.edu FULL TEXT OF THE PROPOSED REGULATION AMENDMENT: UCF-8.008 Solar Thermal Collector

Richardson, Martin C.

263

NOTICE OF PROPOSED REGULATION AMENDMENT Date: August 18, 2005  

E-Print Network [OSTI]

PROPOSED REGULATION AMENDMENT: Philip Fairey, Deputy Director of Florida Solar Energy Center COMMENTS.: Solar Collector Certification 6C7-8.003 SUMMARY OF REGULATION AMENDMENT: This regulation is revised-mail: regulations@mail.ucf.edu FULL TEXT OF THE PROPOSED REGULATION AMENDMENT: 6C7-8.003 Solar Thermal Collector

Wu, Shin-Tson

264

NOTICE OF REGULATION REPEAL Date: July 1, 2010  

E-Print Network [OSTI]

, Florida Solar Energy Center COMMENTS CONCERNING THE REGULATION REPEAL SHOULD BE SUBMITTED WITHIN 14 DAYSNOTICE OF REGULATION REPEAL Date: July 1, 2010 REGULATION TITLE: REGULATION NO.: Solar Thermal REGULATION REPEAL: UCF-8.003 Solar Thermal Collector and PV Module Certification. (1) The Center shall

Wu, Shin-Tson

265

NOTICE OF REGULATION REPEAL Date: July 1, 2010  

E-Print Network [OSTI]

. James Fenton, Director, Florida Solar Energy Center COMMENTS CONCERNING THE REGULATION REPEAL SHOULDNOTICE OF REGULATION REPEAL Date: July 1, 2010 REGULATION TITLE: REGULATION NO.: Solar Thermal OF THE PROPOSED REGULATION REPEAL: UCF-8.005 Solar Thermal and Photovoltaic System Standards and Certification

Wu, Shin-Tson

266

Shrouded inducer pump  

DOE Patents [OSTI]

An improvement in a pump is described including a shrouded inducer, the improvement comprising first and second sealing means which cooperate with a first vortex cell and a series of secondary vortex cells to remove any tangential velocity components from the recirculation flow. 3 figs.

Meng, S.Y.

1989-08-08T23:59:59.000Z

267

Rictor regulates FBXW7-dependent c-Myc and cyclin E degradation in colorectal cancer cells  

SciTech Connect (OSTI)

Highlights: Black-Right-Pointing-Pointer Rictor associates with FBXW7 to form an E3 complex. Black-Right-Pointing-Pointer Knockdown of rictor decreases ubiquitination of c-Myc and cylin E. Black-Right-Pointing-Pointer Knockdown of rictor increases protein levels of c-Myc and cylin E. Black-Right-Pointing-Pointer Overexpression of rictor induces the degradation of c-Myc and cyclin E proteins. Black-Right-Pointing-Pointer Rictor regulation of c-Myc and cyclin E requires FBXW7. -- Abstract: Rictor (Rapamycin-insensitive companion of mTOR) forms a complex with mTOR and phosphorylates and activates Akt. Activation of Akt induces expression of c-Myc and cyclin E, which are overexpressed in colorectal cancer and play an important role in colorectal cancer cell proliferation. Here, we show that rictor associates with FBXW7 to form an E3 complex participating in the regulation of c-Myc and cyclin E degradation. The Rictor-FBXW7 complex is biochemically distinct from the previously reported mTORC2 and can be immunoprecipitated independently of mTORC2. Moreover, knocking down of rictor in serum-deprived colorectal cancer cells results in the decreased ubiquitination and increased protein levels of c-Myc and cyclin E while overexpression of rictor induces the degradation of c-Myc and cyclin E proteins. Genetic knockout of FBXW7 blunts the effects of rictor, suggesting that rictor regulation of c-Myc and cyclin E requires FBXW7. Our findings identify rictor as an important component of FBXW7 E3 ligase complex participating in the regulation of c-Myc and cyclin E protein ubiquitination and degradation. Importantly, our results suggest that elevated growth factor signaling may contribute to decrease rictor/FBXW7-mediated ubiquitination of c-Myc and cyclin E, thus leading to accumulation of cyclin E and c-Myc in colorectal cancer cells.

Guo, Zheng [Markey Cancer Center, The University of Kentucky, 800 Rose Street, Lexington, KY 40536 (United States) [Markey Cancer Center, The University of Kentucky, 800 Rose Street, Lexington, KY 40536 (United States); Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, 1838 Guangzhou Dadao Bei, Guangzhou 510515 (China); Zhou, Yuning [Markey Cancer Center, The University of Kentucky, 800 Rose Street, Lexington, KY 40536 (United States)] [Markey Cancer Center, The University of Kentucky, 800 Rose Street, Lexington, KY 40536 (United States); Evers, B. Mark [Markey Cancer Center, The University of Kentucky, 800 Rose Street, Lexington, KY 40536 (United States) [Markey Cancer Center, The University of Kentucky, 800 Rose Street, Lexington, KY 40536 (United States); Department of Surgery, The University of Kentucky, 800 Rose Street, Lexington, KY 40536 (United States); Wang, Qingding, E-mail: qingding.wang@uky.edu [Markey Cancer Center, The University of Kentucky, 800 Rose Street, Lexington, KY 40536 (United States) [Markey Cancer Center, The University of Kentucky, 800 Rose Street, Lexington, KY 40536 (United States); Department of Surgery, The University of Kentucky, 800 Rose Street, Lexington, KY 40536 (United States)

2012-02-10T23:59:59.000Z

268

Regulation and Moral Hazard in Forest Concessions in Brazil  

E-Print Network [OSTI]

E. M. Designing incentive regulation. Review of IndustrialAgent approach for incentive regulation can be defined,the theory of incentive regulation as a tool to solve the

Balbinotto Neto, Giácomo; Tillmann, Eduardo A; Ratnieks, Ianes

2012-01-01T23:59:59.000Z

269

Harnessing science for environmental regulation  

SciTech Connect (OSTI)

An introductory chapter by Graham frames the issues to be discussed; then the following three chapters describe the formation and character of three organizations. These chapters are written by authors who have each had an active management role in the organization they are writing about: Terry F. Yosie, now at the American Petroleum Institute, who staffed the SAB (Science Advisory Board) while he was at EPA; Robert A. Neal, who headed CIIT (Chemical Industry Institute of Toxicology) before leaving for a position at Vanderbilt University; and Thomas P. Grumbly, former executive director of HEI (Health Effects Institute) now president of Clean Sites, Inc. While these chapters are well written and make a vital contribution to the overall development of the book's themes, the most valuable and enjoyable parts of the book are the succeeding five chapters, which present case studies dealing with EPA's regulatory efforts on unleaded gasoline, perchloroethylene, formaldehyde, nitrates in drinking water, and carbon monoxide. Each of these case studies, nominally historical accounts of how one or more of these (three) organizations participated in the regulatory controversy, offer insight into the broader issues of dealing with, and incorporating into regulations scientific information that has high uncertainty. One of the richest aspects of the five case studies is the extensive use of referenced interviews with identified participants from all aspects of the regulatory process. This material illuminates the motivation, emotions, and goals of the different players, helping the reader to understand their positions and other issues, such as why industry pursues, and EPA and the environmental movement appear to resist, good science; what underlies EPA's preferences for one regulatory option over another; and why scientists are histant to give yes-or-no answers in accord with the real time needs of the regulatory agency.

Graham, J.D. (ed.)

1991-01-01T23:59:59.000Z

270

Laser-Induced Breakdown Spectroscopy  

E-Print Network [OSTI]

LIBS-1 Laser-Induced Breakdown Spectroscopy LIBS ANALYSIS OF METAL SURFACES Last updated: June 17, 2014 #12;LIBS-2 Laser­Induced Breakdown Spectroscopy (LIBS) LIBS ANALYSIS OF METAL SURFACES of species at a distance or in hard­to­reach or hazardous environments. Laser­Induced Breakdown Spectroscopy

Nizkorodov, Sergey

271

Update on Diesel Exhaust Emission Control Technology and Regulations...  

Broader source: Energy.gov (indexed) [DOE]

Update on Diesel Exhaust Emission Control Technology and Regulations Update on Diesel Exhaust Emission Control Technology and Regulations 2004 Diesel Engine Emissions Reduction...

272

Technical Demonstration of 2010 Emissions Regulations over Transient...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

Demonstration of 2010 Emissions Regulations over Transient Operation Technical Demonstration of 2010 Emissions Regulations over Transient Operation Presentation given at DEER 2006,...

273

Comparing Emissions Benefits from Regulating Heavy Vehicle Idling...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

Emissions Benefits from Regulating Heavy Vehicle Idling Comparing Emissions Benefits from Regulating Heavy Vehicle Idling 2005 Diesel Engine Emissions Reduction (DEER) Conference...

274

A trophic cascade regulates salt marsh primary production  

E-Print Network [OSTI]

) Nutrient supply is widely thought to regulate primary production of many ecosystems including salt marshes, predator regulation of marine macrophyte production via trophic cascades (kelps, seagrasses, intertidal

Bertness, Mark D.

275

Air Pollution Control Regulations: No. 13 - Particulate Emissions...  

Broader source: Energy.gov (indexed) [DOE]

Environmental Regulations Provider Department of Environmental Management The purpose of this regulation is to limit emissions of particulate matter from fossil fuel fired and...

276

Air Pollution Control Regulations: No. 41 - Nox Budget Trading...  

Broader source: Energy.gov (indexed) [DOE]

Savings Category Fuel Cells Program Info State Rhode Island Program Type Environmental Regulations Provider Department of Environmental Management These regulations establish a...

277

Office of the Assistant General Counsel for Legislation, Regulation...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Office of the Assistant General Counsel for Legislation, Regulation and Energy Efficiency Office of the Assistant General Counsel for Legislation, Regulation and Energy...

278

Contacts for the Assistant General Counsel for Legislation, Regulation...  

Energy Savers [EERE]

Legislation, Regulation, and Energy Efficiency Contacts for the Assistant General Counsel for Legislation, Regulation, and Energy Efficiency Office of the Assistant General Counsel...

279

EO 13211: Regulations That Significantly Affect Energy Supply...  

Energy Savers [EERE]

1: Regulations That Significantly Affect Energy Supply, Distribution, or Use EO 13211: Regulations That Significantly Affect Energy Supply, Distribution, or Use I am requiring that...

280

Update on Diesel Exhaust Emission Control Technology and Regulations  

Broader source: Energy.gov (indexed) [DOE]

Control Technology and Regulations Tim Johnson August 2004 2 Diesel emission control technology is making significant progress * Diesel regulations are getting tighter in all...

Note: This page contains sample records for the topic "venezuela regulation induced" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


281

Air Emissions Operating Permit Regulations for the Purposes of...  

Broader source: Energy.gov (indexed) [DOE]

Regulations Provider Department of Environmental Quality The Air Emissions Operating Permit Regulations for the Purpose of Title V of the Federal Clean Air Act make the state...

282

Incomplete Environmental Regulation, Imperfect Competition, and Emissions Leakage  

E-Print Network [OSTI]

D. (2005), ‘ Economic impacts of RGGI under the proposed SWGenvironmental regulation (RGGI, 2007; CEC 2006c). Emissionsfrom environmental regulation (RGGI, 2007; CCAP, 2005). In a

Fowlie, Meredith

2007-01-01T23:59:59.000Z

283

REEEP/UNIDO Sustainable Energy Regulation and Policymaking for...  

Open Energy Info (EERE)

REEEPUNIDO Sustainable Energy Regulation and Policymaking for Africa Toolkit < REEEP Jump to: navigation, search Tool Summary LAUNCH TOOL Name: Sustainable Energy Regulation and...

284

Guide to Federal Regulation of Sales of Imported Electricity...  

Broader source: Energy.gov (indexed) [DOE]

Federal Regulation of Sales of Imported Electricity in Canada, Mexico and the United States Guide to Federal Regulation of Sales of Imported Electricity in Canada, Mexico and the...

285

Hazardous Waste Management Standards and Regulations (Kansas)  

Broader source: Energy.gov [DOE]

This act states the standards and regulations for the management of hazardous waste. No person shall construct, modify or operate a hazardous waste facility or otherwise dispose of hazardous waste...

286

Regulating new construction in historic areas  

E-Print Network [OSTI]

This study is an examination of how the restrictiveness of different design regulations impacts the process of new construction in historic areas. The North End, South End, and Back Bay neighborhoods of Boston were identified ...

Sellers-Garcia, Oliver

2006-01-01T23:59:59.000Z

287

Essays on entry regulation, institutions, and development  

E-Print Network [OSTI]

This thesis is a collection of three essays on entry regulation, institutions, and development.Chapter 1 examines the effect of a business registration reform in Mexico on economic activity. This reform made registration ...

Bruhn, Miriam

2007-01-01T23:59:59.000Z

288

Is Conservation a Legitimate Goal of Regulation?  

E-Print Network [OSTI]

Conservation of energy is a frequently cited goal of utility rate regulation. Implementing this goal through modification of consumer behavior has been achieved with varying degrees of success through rate design, incentive programs, direct load...

Goble, G. L.

1984-01-01T23:59:59.000Z

289

Book review Photosynthesis: Regulation under Varying Light  

E-Print Network [OSTI]

pages); (4) Leaf heliotropism, solar tracking and regulation of light interception (10 pages); (5 topic of heliotropism (a subject of interest to Rama Das), and of the transgenic and biotechnological

Govindjee "Gov"

290

Regulation of Branching by Phytochrome and Phytohormones  

E-Print Network [OSTI]

Light is the fundamental source of energy and information throughout the plant life cycle. Light signals regulate plant architecture and branching, key processes that determine biomass production and grain yield. Low red (R) to far-red (FR) light...

Krishnareddy, Srirama R.

2012-07-16T23:59:59.000Z

291

Plant phytotoxicity: A self-regulating pathway  

SciTech Connect (OSTI)

During the session on regulating sludge utilization, held at BioCycle's 19th Annual National conference on Composting and Recycling, a participant asked one of the speakers, Dr. Alan Rubin of the US EPA's Office of Water Regulations and Standards, why the plant phytotoxicity pathway should be the most limiting, especially when there is no concern about human or animal health. The question related specifically to copper being the most limiting metal concentration limit for many sludge composting and land application programs under the proposed Part 503 regulations. And the most limiting pathway for copper is Pathway 7, sludge-soil-plant phytotoxicity. Rubin responded that the regulation is supposed to protect both human health and the environment, e.g. plants and animals other than humans.

Not Available

1989-07-01T23:59:59.000Z

292

State Natural Gas Regulation Act (Nebraska)  

Broader source: Energy.gov [DOE]

This act gives the Nebraska Public Service Commission authority to regulate natural gas utilities and pipelines within the state, except as provided for in the Nebraska Natural Gas Pipeline Safety...

293

certification, compliance and enforcement regulations for Commercial...  

Broader source: Energy.gov (indexed) [DOE]

no sense". The regulations define the basic model as any product that has a different energy use or efficiency level. It does not allow for modeling the performance of our...

294

Comprehensive Everglades Restoration Plan Regulation Act (Florida)  

Broader source: Energy.gov [DOE]

This Act enacts the Comprehensive Everglades Restoration Plan, which is a joint state and federal effort to provide for the conservation of the Everglades region. The plan regulates land and water...

295

Issues paper on radiation site cleanup regulations  

SciTech Connect (OSTI)

EPA prepared the document to present issues, approaches, and preliminary analyses related to its development of radiation site cleanup regulations. It focuses exclusively on issues and approaches related to developing cleanup regulations; it does not address issues specific to waste management regulations, which will be addressed in a separate document. The first three chapters discuss Significant Issues, Regulatory Approaches, and Summary and Next Steps. Appendix A presents background information on radioactive waste and provides additional details of EPA coordination of its rulemaking effort. Appendix B discusses statutory authorities upon which EPA may base its cleanup regulations. Appendix C is a copy of the EPA/NRC MOU. Appendix D discusses the issues raised in NRC's Enhanced Participatory Rulemaking on Radiological Criteria for Decommissioning, in which EPA participated. Appendix E is a list of acronyms, and Appendix F is a glossary of terms used throughout the document.

Not Available

1993-09-01T23:59:59.000Z

296

Environment induced incoherent controllability  

E-Print Network [OSTI]

We prove that the environment induced entanglement between two non interacting, two-dimensional quantum systems S and P can be used to control the dynamics of S by means of the initial state of P. Using a simple, exactly solvable model, we show that both accessibility and controllability of S can be achieved under suitable conditions on the interaction of S and P with the environment.

Raffaele Romano; Domenico D'Alessandro

2005-11-08T23:59:59.000Z

297

Regulation of the genes involved in nitrification.  

SciTech Connect (OSTI)

OAK-B135 This project focuses on the characterization of the regulation of the genes involved in nitrification in the bacterium Nitrosomonas europaea. The key genes in the nitrification pathway, amo and hao, are present in multiple copies in the genome. The promoters for these genes were identified and characterized. It was shown that there were some differences in the transcriptional regulation of the copies of these genes.

Arp, D.J.; Sayavedra-Soto, L.A.

2003-08-14T23:59:59.000Z

298

Smart Grid Newsletter ? The Regulators Role in Grid Modernization...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

the National Energy Technology Laboratory Leadership from state regulators can make the Smart Grid a reality In previous articles we discussed the principal characteristics that...

299

Apigenin suppresses migration and invasion of transformed cells through down-regulation of C-X-C chemokine receptor 4 expression  

SciTech Connect (OSTI)

Environmental exposure to arsenic is known to cause various cancers. There are some potential relationships between cell malignant transformation and C-X-C chemokine receptor type 4 (CXCR4) expressions. Metastasis, one of the major characteristics of malignantly transformed cells, contributes to the high mortality of cells. CXCR4 and its natural chemokine ligand C-X-C motif ligand 12 (CXCL12) play a critical role in metastasis. Therefore, identification of nutritional factors which are able to inhibit CXCR4 is important for protection from environmental arsenic-induced carcinogenesis and for abolishing metastasis of malignantly transformed cells. The present study demonstrates that apigenin (4?,5,7-trihydroxyflavone), a natural dietary flavonoid, suppressed CXCR4 expression in arsenic-transformed Beas-2B cells (B-AsT) and several other types of transformed/cancer cells in a dose- and time-dependent manner. Neither proteasome nor lysosome inhibitor had any effect in reducing the apigenin-induced down-regulation of CXCR4, indicating that apigenin-induced down-regulation of CXCR4 is not due to proteolytic degradation. The down-regulation of CXCR4 is mainly due to the inhibition of nuclear factor ?B (NF-?B) transcriptional activity. Apigenin also abolished migration and invasion of transformed cells induced by CXCL12. In a xenograft mouse model, apigenin down-regulated CXCR4 expression and suppressed tumor growth. Taken together, our results show that apigenin is a novel inhibitor of CXCR4 expression. This dietary flavonoid has the potential to suppress migration and invasion of transformed cells and prevent environmental arsenic-induced carcinogenesis. - Highlights: • Apigenin has a potential in preventing environmental arsenic induced carcinogenesis. • Apigenin suppresses CXCR4 in malignant transformed cells in vitro and in vivo. • The down-regulation of CXCR4 is mainly due to inhibition of NF-?B activity.

Wang, Lei; Kuang, Lisha; Hitron, John Andrew; Son, Young-Ok; Wang, Xin; Budhraja, Amit [Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, KY 40536 (United States); Lee, Jeong-Chae [Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, KY 40536 (United States); Institute of Oral Biosciences and BK21 Program, Research Center of Bioactive Materials, Chonbuk National University, Jeonju 561-756 (Korea, Republic of); Pratheeshkumar, Poyil [Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, KY 40536 (United States); Chen, Gang [Department of Internal Medicine, University of Kentucky College of Medicine, Lexington, KY 40536 (United States); Zhang, Zhuo [Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, KY 40536 (United States); Luo, Jia [Department of Internal Medicine, University of Kentucky College of Medicine, Lexington, KY 40536 (United States); Shi, Xianglin, E-mail: xshi5@email.uky.edu [Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, KY 40536 (United States)

2013-10-01T23:59:59.000Z

300

IKK{epsilon} modulates RSV-induced NF-{kappa}B-dependent gene transcription  

SciTech Connect (OSTI)

Respiratory syncytial virus (RSV), a negative-strand RNA virus, is the most common cause of epidemic respiratory disease in infants and young children. RSV infection of airway epithelial cells induces the expression of immune/inflammatory genes through the activation of a subset of transcription factors, including Nuclear Factor-{kappa}B (NF-{kappa}B). In this study we have investigated the role of the non canonical I{kappa}B kinase (IKK){epsilon} in modulating RSV-induced NF-{kappa}B activation. Our results show that inhibition of IKK{epsilon} activation results in significant impairment of viral-induced NF-{kappa}B-dependent gene expression, through a reduction in NF-{kappa}B transcriptional activity, without changes in nuclear translocation or DNA-binding activity. Absence of IKK{epsilon} results in a significant decrease of RSV-induced NF-{kappa}B phosphorylation on serine 536, a post-translational modification important for RSV-induced NF-{kappa}B-dependent gene expression, known to regulate NF-{kappa}B transcriptional activity without affecting nuclear translocation. This study identifies a novel mechanism by which IKK{epsilon} regulates viral-induced cellular signaling.

Bao Xiaoyong; Indukuri, Hemalatha; Liu Tianshuang; Liao Suiling [Department of Pediatrics, University of Texas Medical Branch, Galveston, TX (United States); Tian, Bing; Brasier, Allan R. [Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX (United States); Garofalo, Roberto P. [Department of Pediatrics, University of Texas Medical Branch, Galveston, TX (United States); Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX (United States); Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, TX (United States); Casola, Antonella, E-mail: ancasola@utmb.ed [Department of Pediatrics, University of Texas Medical Branch, Galveston, TX (United States); Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX (United States); Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, TX (United States)

2010-12-20T23:59:59.000Z

Note: This page contains sample records for the topic "venezuela regulation induced" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


301

Method for inducing hypothermia  

DOE Patents [OSTI]

Systems for phase-change particulate slurry cooling equipment and methods to induce hypothermia in a patient through internal and external cooling are provided. Subcutaneous, intravascular, intraperitoneal, gastrointestinal, and lung methods of cooling are carried out using saline ice slurries or other phase-change slurries compatible with human tissue. Perfluorocarbon slurries or other slurry types compatible with human tissue are used for pulmonary cooling. And traditional external cooling methods are improved by utilizing phase-change slurry materials in cooling caps and torso blankets.

Becker, Lance B. (Chicago, IL); Hoek, Terry Vanden (Chicago, IL); Kasza, Kenneth E. (Palos Park, IL)

2008-09-09T23:59:59.000Z

302

Method for inducing hypothermia  

DOE Patents [OSTI]

Systems for phase-change particulate slurry cooling equipment and methods to induce hypothermia in a patient through internal and external cooling are provided. Subcutaneous, intravascular, intraperitoneal, gastrointestinal, and lung methods of cooling are carried out using saline ice slurries or other phase-change slurries compatible with human tissue. Perfluorocarbon slurries or other slurry types compatible with human tissue are used for pulmonary cooling. And traditional external cooling methods are improved by utilizing phase-change slurry materials in cooling caps and torso blankets.

Becker, Lance B. (Chicago, IL); Hoek, Terry Vanden (Chicago, IL); Kasza, Kenneth E. (Palos Park, IL)

2003-04-15T23:59:59.000Z

303

Electromagnetic Induced Gravitational Perturbations  

E-Print Network [OSTI]

We study the physical consequences of two diffferent but closely related perturbation schemes applied to the Einstein-Maxwell equations. In one case the starting space-time is flat while in the other case it is Schwarzschild. In both cases the perturbation is due to a combined electric and magnetic dipole field. We can see, within the Einstein-Maxwell equations a variety of physical consequences. They range from induced gravitational energy-momentum loss, to a well defined spin angular momentum with its loss and a center-of-mass with its equations of motion.

T. M. Adamo; E. T. Newman

2008-07-23T23:59:59.000Z

304

Method for inducing hypothermia  

DOE Patents [OSTI]

Systems for phase-change particulate slurry cooling equipment and methods to induce hypothermia in a patient through internal and external cooling are provided. Subcutaneous, intravascular, intraperitoneal, gastrointestinal, and lung methods of cooling are carried out using saline ice slurries or other phase-change slurries compatible with human tissue. Perfluorocarbon slurries or other slurry types compatible with human tissue are used for pulmonary cooling. And traditional external cooling methods are improved by utilizing phase-change slurry materials in cooling caps and torso blankets.

Becker, Lance B.; Hoek, Terry Vanden; Kasza, Kenneth E.

2005-11-08T23:59:59.000Z

305

May 22, 2002 Advanced Workshop in Regulation and Competition  

E-Print Network [OSTI]

%Restructuring &Strategies under Competition and Deregulation %Incentive Regulation %Market Innovation Who should

Lin, Xiaodong

306

Advanced Workshop in Regulation and Competition Annual Western Conference  

E-Print Network [OSTI]

and Deregulation %Incentive Regulation %Auctions Who should attend: &Industry Economists %Marketing and Regulatory

Lin, Xiaodong

307

Rules and Regulations for Hazardous Waste Management (Rhode Island)  

Broader source: Energy.gov [DOE]

These regulations establish permitting and operational requirements for hazardous waste facilities. They are designed to minimize...

308

NOTICE OF PROPOSED REGULATION AMENDMENT Date: April 15, 2009  

E-Print Network [OSTI]

REGULATION AMENDMENT: Philip Fairey, Deputy Director, Florida Solar Energy Center COMMENTS CONCERNING.: Solar Thermal Collector and PV Module Testing Standards UCF-8.002 SUMMARY OF REGULATION AMENDMENT-mail: regulations@mail.ucf.edu FULL TEXT OF THE PROPOSED REGULATION AMENDMENT: UCF6C7-8.002 Solar Thermal Collector

Wu, Shin-Tson

309

NOTICE OF PROPOSED REGULATION AMENDMENT Date: November 8, 2011  

E-Print Network [OSTI]

PROPOSED REGULATION AMENDMENT: Dr. James Fenton, Director, Florida Solar Energy Center COMMENTS CONCERNING.: Solar Thermal and Photovoltaic System Standards UCF-8.010 and Certification SUMMARY OF REGULATION-mail: regulations@mail.ucf.edu FULL TEXT OF THE PROPOSED REGULATION AMENDMENT: UCF-8.010 Solar Thermal

Richardson, Martin C.

310

NOTICE OF PROPOSED REGULATION AMENDMENT Date: August 18, 2005  

E-Print Network [OSTI]

.: Florida Solar Energy Center Operations 6C7-8.001 SUMMARY OF REGULATION AMENDMENT: This regulation is revised to update the location of the Florida Solar Energy Center. This regulation is amended also of Florida Solar Energy Center COMMENTS CONCERNING THE PROPOSED REGULATION AMENDMENT SHOULD BE SUBMITTED

Wu, Shin-Tson

311

NOTICE OF PROPOSED REGULATION AMENDMENT Date: November 8, 2011  

E-Print Network [OSTI]

.: Florida Solar Energy Center Operations UCF-8.006 SUMMARY OF REGULATION: This regulation is an updated-mail: regulations@mail.ucf.edu FULL TEXT OF THE PROPOSED REGULATION AMENDMENT: UCF-8.006 Florida Solar Energy Center AMENDMENT: Dr. James Fenton, Director, Florida Solar Energy Center COMMENTS CONCERNING THE PROPOSED

Richardson, Martin C.

312

NOTICE OF PROPOSED REGULATION AMENDMENT Date: April 15, 2009  

E-Print Network [OSTI]

REGULATION AMENDMENT: Philip Fairey, Deputy Director, Florida Solar Energy Center COMMENTS CONCERNING.: Solar Thermal Collector and PV Module Certification UCF-8.003 SUMMARY OF REGULATION AMENDMENT-mail: regulations@mail.ucf.edu FULL TEXT OF THE PROPOSED REGULATION AMENDMENT: UCF6C7-8.003 Solar Thermal Collector

Wu, Shin-Tson

313

NOTICE OF PROPOSED REGULATION AMENDMENT Date: April 15, 2009  

E-Print Network [OSTI]

.: Florida Solar Energy Center Operations UCF-8.001 SUMMARY OF REGULATION AMENDMENT: The regulation Director, Florida Solar Energy Center COMMENTS CONCERNING THE PROPOSED REGULATION AMENDMENT SHOULD TEXT OF THE PROPOSED REGULATION AMENDMENT: UCF6C7-8.001 Florida Solar Energy Center Operations. (1

Wu, Shin-Tson

314

Genetic regulation of dietary restriction-induced longevity in Caenorhabditis elegans  

E-Print Network [OSTI]

Dietary restriction (DR), the limitation of food intake below the ad libidum (AL) level without malnutrition, extends mean and maximum lifespan in every organism in which it has been tested. Perhaps even more significantly, ...

Bishop, Nicholas A

2007-01-01T23:59:59.000Z

315

E-Print Network 3.0 - antipsychotic-induced gene regulation Sample...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

and Information Sciences 42 Estimation of Gene Induction Enables a Relevance-Based Ranking of Gene Sets Summary: methods which are focused on significance, our approach...

316

RESEARCH ARTICLE Effectiveness of pulse flows in a regulated river for inducing  

E-Print Network [OSTI]

) in a reach of the Puntledge River where water is diverted for power generation, resulting in stable low flows (i.e., turbine out flows), and/or the presence of non-optimal environmental conditions (i.e., cold, Courtenay, BC V9N 2Z5, Canada B. Mossop BC Hydro, 6911 Southpoint Drive, Burnaby, BC V3N 4X8, Canada S. G

Hinch, Scott G.

317

microRNA-223 Regulates Macrophage Polarization and Diet-induced Insulin Resistance  

E-Print Network [OSTI]

network for macrophage activation and adipose tissue function. We have examined the activity of microRNA-223 (miR-223) and its role in controlling macrophage functions in adipose tissue inflammation and systemic insulinresistance. miR-223-/- mice on a...

Meng, Cong

2013-05-01T23:59:59.000Z

318

E-Print Network 3.0 - acid-induced p-glycoprotein up-regulation...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

1999. 39:36198 BIOCHEMICAL, CELLULAR, Summary: .ramachandra@canjii.com; pasta@helix.nih.gov; and mgottesman@nih.gov KEY WORDS: multidrug resistance, P-glycoprotein, drug......

319

Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival  

E-Print Network [OSTI]

for post-menopausal osteoporosis (Sambrook and Cooper, 2006). Estrogen and ERs are important for bone and Musculoskeletal Biology, Wyeth Research, Collegeville, PA, USA Estrogen deficiency in menopause is a major cause of osteoporosis in women. Estrogen acts to maintain the appropriate ratio between bone-forming osteoblasts

Brown, Myles

320

A DNA Damage-Induced, SOS-Independent Checkpoint Regulates Cell Division in Caulobacter crescentus  

E-Print Network [OSTI]

Cells must coordinate DNA replication with cell division, especially during episodes of DNA damage. The paradigm for cell division control following DNA damage in bacteria involves the SOS response where cleavage of the ...

Modell, Joshua W.

Note: This page contains sample records for the topic "venezuela regulation induced" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


321

Selective effect of the metallocarcinogen beryllium on hormonal regulation of gene expression in cultured cells  

SciTech Connect (OSTI)

Effects of the metallocarcinogen beryllium on regulation of gene expression were assessed by analysis of hormonal regulation of synthesis of tyrosine aminotransferase in beryllium-treated hepatoma cell cultures. Cell growth was not affected by exposure of the cells to 1 ..mu..M BeSO/sub 4/ throughout their 4- to 5-day growth cycle. In cells pretreated in this way, the induction by glucocorticoids was specifically impaired, the extent of induced enzyme synthesis being reduced about 50%. Inductions by insulin or cyclic adenosine 3':5'-monophosphate were not influenced by the metal. The results suggest that low concentrations of beryllium selectively interfere with regulatory mechanisms controlling transcriptional events in gene expression.

Perry, S.T.; Kulkarni, S.B.; Lee, K.L.; Kenney, F.T.

1982-02-01T23:59:59.000Z

322

Regulation of bcl-2 proto-oncogene expression during normal human lymphocyte proliferation  

SciTech Connect (OSTI)

The bcl-2 and c-myc proto-oncogenes are brought into juxtaposition with the immuno-globulin heavy chain locus in particular B-cell lymphomas, resulting in high levels of constitutive accumulation of their messenger RNAs. Precisely how the products of the bcl-2 and c-myc genes contribute to tumorigenesis is unknown, but observations that c-myc expression is rapidly induced in nonneoplastic lymphocytes upon stimulation of proliferation raise the possibility that this proto-oncogene is involved in the control of normal cellular growth. In addition to c-myc, the bcl-2 proto-oncogene also was expressed in normal human B and T lymphocytes after stimulation with appropriate mitogens. Comparison of the regulation of the expression of these proto-oncogenes demonstrated marked differences and provided evidence that, in contrast to c-myc, levels of bcl-2 messenger RNA are regulated primarily though transcriptional mechanisms. 10 references, 3 figures.

Reed, J.C.; Tsujimoto, Y.; Alpers, J.D.; Croce, C.M.; Nowell, P.C.

1987-06-05T23:59:59.000Z

323

Transport and Induced Elastic Stress  

E-Print Network [OSTI]

Title: Variational Approach in Studying the Mixture of the Fluids: Transport and Induced Elastic Stress Abstract: From the energetic point of view, most ...

324

Environmental regulations handbook for enhanced oil recovery  

SciTech Connect (OSTI)

This handbook is intended to assist owners and operators of enhanced oil recovery (EOR) operations in acquiring some introductory knowledge of the various state agencies, the US Environmental Protection Agency, and the many environmental laws, rules and regulations which can have jurisdiction over their permitting and compliance activities. It is a compendium of summarizations of environmental rules. It is not intended to give readers specific working details of what is required from them, nor can it be used in that manner. Readers of this handbook are encouraged to contact environmental control offices nearest to locations of interest for current regulations affecting them.

Madden, M.P. [National Inst. for Petroleum and Energy Research, Bartlesville, OK (United States); Blatchford, R.P.; Spears, R.B. [Spears and Associates, Inc., Tulsa, OK (United States)

1991-12-01T23:59:59.000Z

325

The cAMP Response Element Binding protein (CREB) is activated by Insulin-like Growth Factor-1 (IGF-1) and regulates myostatin gene expression in skeletal myoblast  

SciTech Connect (OSTI)

Highlights: •IGF-1 induces the activation of CREB via IGF-1R/PI3K/PLC signaling pathway. •Calcium dependent signaling pathways regulate myostatin gene expression. •IGF-1 regulates myostatin gene expression via CREB transcription in skeletal myoblast. -- Abstract: Myostatin, a member of the Transforming Growth Factor beta (TGF-?) superfamily, plays an important role as a negative regulator of skeletal muscle growth and differentiation. We have previously reported that IGF-1 induces a transient myostatin mRNA expression, through the activation of the Nuclear Factor of Activated T cells (NFAT) in an IP{sub 3}/calcium-dependent manner. Here we examined the activation of CREB transcription factor as downstream targets of IGF-1 during myoblast differentiation and its role as a regulator of myostatin gene expression. In cultured skeletal myoblast, IGF-1 induced the phosphorylation and transcriptional activation of CREB via IGF-1 Receptor/Phosphatidylinositol 3-Kinase (PI3K)/Phospholipase C gamma (PLC ?), signaling pathways. Also, IGF-1 induced calcium-dependent molecules such as Calmodulin Kinase II (CaMK II), Extracellular signal-regulated Kinases (ERK), Protein Kinase C (PKC). Additionally, we examined myostatin mRNA levels and myostatin promoter activity in differentiated myoblasts stimulated with IGF-1. We found a significant increase in mRNA contents of myostatin and its reporter activity after treatment with IGF-1. The expression of myostatin in differentiated myoblast was downregulated by the transfection of siRNA–CREB and by pharmacological inhibitors of the signaling pathways involved in CREB activation. By using pharmacological and genetic approaches together these data demonstrate that IGF-1 regulates the myostatin gene expression via CREB transcription factor during muscle cell differentiation.

Zuloaga, R. [Facultad de Ciencias Biológicas, Universidad Andres Bello, Santiago (Chile)] [Facultad de Ciencias Biológicas, Universidad Andres Bello, Santiago (Chile); Fuentes, E.N.; Molina, A. [Facultad de Ciencias Biológicas, Universidad Andres Bello, Santiago (Chile) [Facultad de Ciencias Biológicas, Universidad Andres Bello, Santiago (Chile); Interdisciplinary Center for Aquaculture Research (INCAR), Víctor Lamas 1290, PO Box 160-C, Concepción (Chile); Valdés, J.A., E-mail: jvaldes@unab.cl [Facultad de Ciencias Biológicas, Universidad Andres Bello, Santiago (Chile); Interdisciplinary Center for Aquaculture Research (INCAR), Víctor Lamas 1290, PO Box 160-C, Concepción (Chile)

2013-10-18T23:59:59.000Z

326

MicroRNA Regulation of IGF-1  

E-Print Network [OSTI]

an incredible learning experience. Finally, I would like to thank my friends and family for their continuous love and support. 4 ABSTRACT MicroRNA Regulation of IGF. (May 2013) Kayla Anne Filan McEnery Department of Biochemistry & Biophysics Texas A...

McEnery, Kayla Anne Filan

2013-02-04T23:59:59.000Z

327

RULES AND REGULATIONS GOVERNING PUBLIC USE  

E-Print Network [OSTI]

.12 Restrictions. 327.13 Explosives, firearms, other weapons and fireworks. 327.14 Public property. 327 of Engineers. ALL OTHER FEDERAL, STATE AND LOCAL LAWS AND REGULATIONS REMAIN IN FULL FORCE AND EFFECT WHERE force and effect on project lands or waters which are outgranted by the District Commander by lease

US Army Corps of Engineers

328

Student Regulations and Procedures Academic Division  

E-Print Network [OSTI]

Student Regulations and Procedures Academic Division 2007/2008 11 Students Union Code information regarding their course, tuition fees, award ceremonies and other matters www.mmu.ac.uk/academic's Articles of Government (Article 1.1). As prescribed in the Articles of Government (Article 12

329

RULES AND REGULATIONS Title 7--AGRICULTURE  

E-Print Network [OSTI]

RULES AND REGULATIONS Title 7--AGRICULTURE DEPARTMENT OF AGRICULTURE [7 PA. CODE CH. 130b] Nutrient Management Certification [35 Pa.B. 6504] The Department of Agriculture (Department), under section 7(a or the Senate or House Agricultural and Rural Affairs Committees regarding the proposed rulemaking

Guiltinan, Mark

330

Voltage regulation in linear induction accelerators  

DOE Patents [OSTI]

Improvement in voltage regulation in a Linear Induction Accelerator wherein a varistor, such as a metal oxide varistor, is placed in parallel with the beam accelerating cavity and the magnetic core. The non-linear properties of the varistor result in a more stable voltage across the beam accelerating cavity than with a conventional compensating resistance.

Parsons, William M. (Santa Fe, NM)

1992-01-01T23:59:59.000Z

331

Voltage regulation in linear induction accelerators  

DOE Patents [OSTI]

Improvement in voltage regulation in a linear induction accelerator wherein a varistor, such as a metal oxide varistor, is placed in parallel with the beam accelerating cavity and the magnetic core is disclosed. The non-linear properties of the varistor result in a more stable voltage across the beam accelerating cavity than with a conventional compensating resistance. 4 figs.

Parsons, W.M.

1992-12-29T23:59:59.000Z

332

FLORIDA BOARD OF GOVERNORS Regulation Development Procedure  

E-Print Network [OSTI]

be any natural person with an interest within the zone of interest protected or regulated who suffers. A substantially affected person shall also mean any association with a majority of natural persons as members, amendment or repeal shall include publication on a clearly marked area on the university's internet website

Wu, Shin-Tson

333

FOOD AND DRINK REGULATIONS Serving hot food  

E-Print Network [OSTI]

of food poisoning increases as time passes. · Hand contact with unwrapped food should be kept to a minimum1 FOOD AND DRINK REGULATIONS Serving hot food Home made hot food may not be served at events conditions must be adhered to: · The caterer must have HSE Food Hygiene Certification, which

O'Mahony, Donal E.

334

LIBRARY REGULATIONS 1. THE LIBRARY POLICY COMMITTEE  

E-Print Network [OSTI]

1 LIBRARY REGULATIONS 1. THE LIBRARY POLICY COMMITTEE 1.1 The Library Policy Committee shall shall be: [i] to formulate proposals in regard to policy matters relating to the Library for consideration by the Academic Council and the Governing Body; [ii] to monitor the implementation of Library

Schellekens, Michel P.

335

Method for regulation of plant lignin composition  

DOE Patents [OSTI]

A method is disclosed for the regulation of lignin composition in plant tissue. Plants are transformed with a gene encoding an active F5H gene. The expression of the F5H gene results in increased levels of syringyl monomer providing a lignin composition more easily degraded with chemicals and enzymes.

Chapple, Clint (West Lafayette, IN)

1999-01-01T23:59:59.000Z

336

Regulative and voluntary instruments for responsible forest  

E-Print Network [OSTI]

carrotssermonssticks PES Comand and control Taxes and subsibies ­ Directness + Education ­Useofeconomicincentives,700 ha di farmland producing corn converted to organic · 92% of the area involved in the program · 200) A similar type of classification " Regulative instruments promoted by public institutions: international

Pettenella, Davide

337

Denman Forestry Issues Series: Washington's Forest Regulations  

E-Print Network [OSTI]

Denman Forestry Issues Series: Washington's Forest Regulations and Their Impacts on The Private College of Forest Resources continued its Denman Forestry Issues Series on May 30, 2001. Alumni landowners. Policy analysts and speakers representing the Washington Farm Forestry Assn., Washington Forest

Borenstein, Elhanan

338

Effects of caseinomacropeptide (CMP) on digestion regulation  

E-Print Network [OSTI]

Effects of caseinomacropeptide (CMP) on digestion regulation M Yvon S Beucher P Guilloteau2 I Le sums up the knowledge concerning its effects on the digestive function. Part 1 recalls the origin to be defined accurately. Part 2 summarizes the effects of CMP on digestive secretions. The major effect

Paris-Sud XI, Université de

339

RULES AND REGULATIONS ENVIRONMENTAL QUALITY BOARD  

E-Print Network [OSTI]

on best management practices to protect and restore that important resource, and to meet PennsylvaniaRULES AND REGULATIONS ENVIRONMENTAL QUALITY BOARD [25 PA. CODE CHS. 91 AND 92] Concentrated Animal Feeding Operations and Other Agricultural Operations [35 Pa.B. 5796] The Environmental Quality Board

Guiltinan, Mark

340

Global protein phosphorylation dynamics during deoxynivalenol-induced ribotoxic stress response in the macrophage  

SciTech Connect (OSTI)

Deoxynivalenol (DON), a trichothecene mycotoxin produced by Fusarium that commonly contaminates food, is capable of activating mononuclear phagocytes of the innate immune system via a process termed the ribotoxic stress response (RSR). To encapture global signaling events mediating RSR, we quantified the early temporal (? 30 min) phosphoproteome changes that occurred in RAW 264.7 murine macrophage during exposure to a toxicologically relevant concentration of DON (250 ng/mL). Large-scale phosphoproteomic analysis employing stable isotope labeling of amino acids in cell culture (SILAC) in conjunction with titanium dioxide chromatography revealed that DON significantly upregulated or downregulated phosphorylation of 188 proteins at both known and yet-to-be functionally characterized phosphosites. DON-induced RSR is extremely complex and goes far beyond its prior known capacity to inhibit translation and activate MAPKs. Transcriptional regulation was the main target during early DON-induced RSR, covering over 20% of the altered phosphoproteins as indicated by Gene Ontology annotation and including transcription factors/cofactors and epigenetic modulators. Other biological processes impacted included cell cycle, RNA processing, translation, ribosome biogenesis, monocyte differentiation and cytoskeleton organization. Some of these processes could be mediated by signaling networks involving MAPK-, NF?B-, AKT- and AMPK-linked pathways. Fuzzy c-means clustering revealed that DON-regulated phosphosites could be discretely classified with regard to the kinetics of phosphorylation/dephosphorylation. The cellular response networks identified provide a template for further exploration of the mechanisms of trichothecenemycotoxins and other ribotoxins, and ultimately, could contribute to improved mechanism-based human health risk assessment. - Highlights: ? Mycotoxin deoxynivalenol (DON) induces immunotoxicity via ribotoxic stress response. ? SILAC phosphoproteomics using TiO{sub 2} was applied to DON-treated RAW 264.7 cells. ? DON induces extensive protein phosphorylation changes involving 188 phosphoproteins. ? The main target of early DON-induced RSR is transcriptional regulation. ? Early DON-induced RSR is mediated by MAPK-, NF?B-, AKT- and AMPK-linked pathways.

Pan, Xiao [Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824 (United States); Center for Integrative Toxicology, Michigan State University, East Lansing, MI 48824 (United States); Whitten, Douglas A. [Research Technology Support Facility, Proteomics Core, Michigan State University, East Lansing, MI 48824 (United States); Wu, Ming [Department of Computer Science and Engineering, Michigan State University, East Lansing, MI 48824 (United States); Chan, Christina [Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824 (United States); Department of Computer Science and Engineering, Michigan State University, East Lansing, MI 48824 (United States); Wilkerson, Curtis G. [Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824 (United States); Research Technology Support Facility, Proteomics Core, Michigan State University, East Lansing, MI 48824 (United States); Pestka, James J., E-mail: pestka@msu.edu [Center for Integrative Toxicology, Michigan State University, East Lansing, MI 48824 (United States); Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI 48824 (United States); Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI 48824 (United States)

2013-04-15T23:59:59.000Z

Note: This page contains sample records for the topic "venezuela regulation induced" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


341

Hedgehog pathway regulators influence cervical cancer cell proliferation, survival and migration  

SciTech Connect (OSTI)

Highlights: Black-Right-Pointing-Pointer Unknown cellular mutations complement papillomavirus-induced carcinogenesis. Black-Right-Pointing-Pointer Hedgehog pathway components are expressed by cervical cancer cells. Black-Right-Pointing-Pointer Hedgehog pathway activators and inhibitors regulate cervical cancer cell biology. Black-Right-Pointing-Pointer Cell immortalization by papillomavirus and activation of Hedgehog are independent. -- Abstract: Human papillomavirus (HPV) infection is considered to be a primary hit that causes cervical cancer. However, infection with this agent, although needed, is not sufficient for a cancer to develop. Additional cellular changes are required to complement the action of HPV, but the precise nature of these changes is not clear. Here, we studied the function of the Hedgehog (Hh) signaling pathway in cervical cancer. The Hh pathway can have a role in a number of cancers, including those of liver, lung and digestive tract. We found that components of the Hh pathway are expressed in several cervical cancer cell lines, indicating that there could exists an autocrine Hh signaling loop in these cells. Inhibition of Hh signaling reduces proliferation and survival of the cervical cancer cells and induces their apoptosis as seen by the up-regulation of the pro-apoptotic protein cleaved caspase 3. Our results indicate that Hh signaling is not induced directly by HPV-encoded proteins but rather that Hh-activating mutations are selected in cells initially immortalized by HPV. Sonic Hedgehog (Shh) ligand induces proliferation and promotes migration of the cervical cancer cells studied. Together, these results indicate pro-survival and protective roles of an activated Hh signaling pathway in cervical cancer-derived cells, and suggest that inhibition of this pathway may be a therapeutic option in fighting cervical cancer.

Samarzija, Ivana [Ecole Polytechnique Federale Lausanne (EPFL), Department of Life Sciences, Swiss Institute for Experimental Cancer Research (ISREC), 1015 Lausanne (Switzerland)] [Ecole Polytechnique Federale Lausanne (EPFL), Department of Life Sciences, Swiss Institute for Experimental Cancer Research (ISREC), 1015 Lausanne (Switzerland); Beard, Peter, E-mail: peter.beard@epfl.ch [Ecole Polytechnique Federale Lausanne (EPFL), Department of Life Sciences, Swiss Institute for Experimental Cancer Research (ISREC), 1015 Lausanne (Switzerland)] [Ecole Polytechnique Federale Lausanne (EPFL), Department of Life Sciences, Swiss Institute for Experimental Cancer Research (ISREC), 1015 Lausanne (Switzerland)

2012-08-17T23:59:59.000Z

342

Regulation of Nuclear Localization of Signaling Proteins by Cytokinin  

SciTech Connect (OSTI)

Cytokinins are a class of mitogenic plant hormones that play an important role in most aspects of plant development, including shoot and root growth, vascular and photomorphogenic development and leaf senescence. A model for cytokinin perception and signaling has emerged that is similar to bacterial two-component phosphorelays. In this model, binding of cytokinin to the extracellular domain of the Arabidopsis histidine kinase (AHKs) receptors induces autophosphorylation within the intracellular histidine-kinase domain. The phosphoryl group is subsequently transferred to cytosolic Arabidopsis histidine phosphotransfer proteins (AHPs), which have been suggested to translocate to the nucleus in response to cytokinin treatment, where they then transfer the phosphoryl group to nuclear-localized response regulators (Type-A and Type-B ARRs). We examined the effects of cytokinin on AHP subcellular localization in Arabidopsis and, contrary to expectations, the AHPs maintained a constant nuclear/cytosolic distribution following cytokinin treatment. Furthermore, mutation of the conserved phosphoacceptor histidine residue of the AHP, as well as disruption of multiple cytokinin signaling elements, did not affect the subcellular localization of the AHP proteins. Finally, we present data indicating that AHPs maintain a nuclear/cytosolic distribution by balancing active transport into and out of the nucleus. Our findings suggest that the current models indicating relocalization of AHP protein into the nucleus in response to cytokinin are incorrect. Rather, AHPs actively maintain a consistent nuclear/cytosolic distribution regardless of the status of the cytokinin response pathway.

Kieber, J.J.

2010-05-01T23:59:59.000Z

343

Nickel (II)-induced cytotoxicity and apoptosis in human proximal tubule cells through a ROS- and mitochondria-mediated pathway  

SciTech Connect (OSTI)

Nickel compounds are known to be toxic and carcinogenic in kidney and lung. In this present study, we investigated the roles of reactive oxygen species (ROS) and mitochondria in nickel (II) acetate-induced cytotoxicity and apoptosis in the HK-2 human renal cell line. The results showed that the cytotoxic effects of nickel (II) involved significant cell death and DNA damage. Nickel (II) increased the generation of ROS and induced a noticeable reduction of mitochondrial membrane potential (MMP). Analysis of the sub-G1 phase showed a significant increase in apoptosis in HK-2 cells after nickel (II) treatment. Pretreatment with N-acetylcysteine (NAC) not only inhibited nickel (II)-induced cell death and DNA damage, but also significantly prevented nickel (II)-induced loss of MMP and apoptosis. Cell apoptosis triggered by nickel (II) was characterized by the reduced protein expression of Bcl-2 and Bcl-xL and the induced the protein expression of Bad, Bcl-Xs, Bax, cytochrome c and caspases 9, 3 and 6. The regulation of the expression of Bcl-2-family proteins, the release of cytochrome c and the activation of caspases 9, 3 and 6 were inhibited in the presence of NAC. These results suggest that nickel (II) induces cytotoxicity and apoptosis in HK-2 cells via ROS generation and that the mitochondria-mediated apoptotic signaling pathway may be involved in the positive regulation of nickel (II)-induced renal cytotoxicity.

Wang, Yi-Fen; Shyu, Huey-Wen [Department of Medical Laboratory Sciences and Biotechnology, Fooyin University, Kaohsiung, Taiwan (China)] [Department of Medical Laboratory Sciences and Biotechnology, Fooyin University, Kaohsiung, Taiwan (China); Chang, Yi-Chuang [Department of Nursing, Fooyin University, Kaohsiung, Taiwan (China)] [Department of Nursing, Fooyin University, Kaohsiung, Taiwan (China); Tseng, Wei-Chang [Department of Medical Laboratory Sciences and Biotechnology, Fooyin University, Kaohsiung, Taiwan (China)] [Department of Medical Laboratory Sciences and Biotechnology, Fooyin University, Kaohsiung, Taiwan (China); Huang, Yeou-Lih [Department of Medical Laboratory Science and Biotechnology, Kaohsiung Medical University, Kaohsiung, Taiwan (China)] [Department of Medical Laboratory Science and Biotechnology, Kaohsiung Medical University, Kaohsiung, Taiwan (China); Lin, Kuan-Hua; Chou, Miao-Chen; Liu, Heng-Ling [Department of Medical Laboratory Sciences and Biotechnology, Fooyin University, Kaohsiung, Taiwan (China)] [Department of Medical Laboratory Sciences and Biotechnology, Fooyin University, Kaohsiung, Taiwan (China); Chen, Chang-Yu, E-mail: mt037@mail.fy.edu.tw [Department of Medical Laboratory Sciences and Biotechnology, Fooyin University, Kaohsiung, Taiwan (China)] [Department of Medical Laboratory Sciences and Biotechnology, Fooyin University, Kaohsiung, Taiwan (China)

2012-03-01T23:59:59.000Z

344

Atomic Energy and Radioactive Substances: Licensing and Regulation of Sites: The Nuclear Installations Regulations, 1962   

E-Print Network [OSTI]

These regulations, made by the Minister of Power and the Secretary of State for Scotland acting jointly, prescribe for the purpose of subsection (1)(b) of section one of the Nuclear Installations (Licensing and Insurance) Act, 1959, certain classes...

Wood, Richard; Maclay, John. S.

1962-01-01T23:59:59.000Z

345

Preferences for change: Do individuals prefer voluntary actions, soft regulations, or hard regulations to  

E-Print Network [OSTI]

' environmental attitudes (as assessed using the New Ecological Paradigm scale) had a strong positive relationship states sued the EPA to force the agency to regulate carbon dioxide and other green- house gases (GHGs

Indiana University

346

SirT1 regulates bone mass in vivo through regulation of osteoblast and osteoclast differentiation  

E-Print Network [OSTI]

As mammals age, osteoblast numbers decrease while osteoclast numbers increase, resulting in age-related or post-menopausal osteoporosis. SirT1, the mammalian orthologue of yeast Sir2, has been shown to be a negative regulator ...

Zainabadi, Kayvan

2009-01-01T23:59:59.000Z

347

CALCIUM SULFATE-INDUCED ACCELERATED CORROSION  

E-Print Network [OSTI]

INDUCED ACCELERATED CORROSION Hilary Chikezie Akuezue (M. S.deposit on Caso 4-induced corrosion. This will involve poreAlso, Caso 4 deposit-induced corrosion will be compared with

Akuezue, Hilary Chikezie

2013-01-01T23:59:59.000Z

348

CALCIUM SULFATE-INDUCED ACCELERATED CORROSION  

E-Print Network [OSTI]

10286 CALCIUM SULFATE-INDUCED ACCELERATED CORROSION HilaryCT Calcium Sulf(1te··induced Accelerated Corrosion By Hilaryof the Caso - induced accelerated attack on pure iron and

Akuezue, Hilary Chikezie

2013-01-01T23:59:59.000Z

349

Electromagnetically Induced Flows Michiel de Reus  

E-Print Network [OSTI]

Electromagnetically Induced Flows in Water Michiel de Reus 8 maart 2013 () Electromagnetically Conclusion and future research () Electromagnetically Induced Flows 2 / 56 #12;1 Introduction 2 Maxwell Navier Stokes equations 5 Simulations 6 Conclusion and future research () Electromagnetically Induced

Vuik, Kees

350

FLORIDA ATLANTIC UNVIERSITY NOTICE OF PROPOSED REGULATION REPEAL  

E-Print Network [OSTI]

TITLE AND NUMBER: Statutory References (1.004). SUMMARY: Regulation 1.004 was last amended in 1987 OF REGULATIONS IS: Myrlande Dessalines, Paralegal, Office of the General Counsel, 777 Glades Road, Boca Raton

Richman, Fred

351

Understanding regulation of mRNA by RNA binding proteins  

E-Print Network [OSTI]

Posttranscriptional regulation of mRNA by RNA-binding proteins plays key roles in regulating the transcriptome over the course of development, between tissues and in disease states. The specific interactions between mRNA ...

Robertson, Alexander De Jong

2014-01-01T23:59:59.000Z

352

Oil and Gas Commission General Rules and Regulations (Arkansas)  

Broader source: Energy.gov [DOE]

The Oil and Gas Commission General Rules and Regulations are the body of rules and regulations that relate to natural gas production in Arkansas. The statutory law is found Arkansas Code Annotated...

353

Amino acid regulation of mTORC1  

E-Print Network [OSTI]

Mammalian target of rapamycin complex I (mTORC1) is an atypical Ser/Thr kinase that regulates cellular and organismal growth. Accordingly, mTORC1 has substantial roles in regulating insulin sensitivity and lifespan, and ...

Bar-Peled, Liron

2013-01-01T23:59:59.000Z

354

Energy storage for frequency regulation on the electric grid  

E-Print Network [OSTI]

Ancillary services such as frequency regulation are required for reliable operation of the electric grid. Currently, the same traditional thermal generators that supply bulk power also perform nearly all frequency regulation. ...

Leitermann, Olivia

2012-01-01T23:59:59.000Z

355

Regulatory Takings and Environmental Regulation in NAFTA's Chapter 11  

E-Print Network [OSTI]

for regulation is known only after the investment is sunk. The ex- istence of sunk costs combined with the fact

Karp, Larry S.

356

Electric holding company regulation by multistate compact  

SciTech Connect (OSTI)

This article is divided into five sections. The first section discusses the market and regulatory environment of bulk power sales. The second presents the legal framework for compacting and discusses the minimal constitutional barriers presented by the Compact Clause. The next section discusses the economic considerations inherent in attempting to regulate a national activity through regional authorities. The fourth section more fully develops the administrative and political problems that regional regulation must overcome to be successful. Using the legal, economic, and policy framework developed in the preceding sections, the final section analyzes the proposal encompassed in Senate Bill 2607, a proposal by the Arkansas Public Service Commission and Entergy Corporation to create regional organizations to provide integrated resource planning.

Darr, F.P.

1993-01-01T23:59:59.000Z

357

Environmental radiation exposure: Regulation, monitoring, and assessment  

SciTech Connect (OSTI)

Radioactive releases to the environment from nuclear facilities constitute a public health concern. Protecting the public from such releases can be achieved through the establishment and enforcement of regulatory standards. In the United States, numerous standards have been promulgated to regulate release control at nuclear facilities. Most recent standards are more restrictive than those in the past and require that radioactivity levels be as low as reasonably achievable (ALARA). Environmental monitoring programs and radiological dose assessment are means of ensuring compliance with regulations. Environmental monitoring programs provide empirical information on releases, such as the concentrations of released radioactivity in environmental media, while radiological dose assessment provides the analytical means of quantifying dose exposures for demonstrating compliance.

Chen, S.Y.; Yu, C.; Hong, K.J.

1991-01-01T23:59:59.000Z

358

Development of EPA radiation site cleanup regulations  

SciTech Connect (OSTI)

This paper summarizes the EPA program to develop radiation site cleanup and identifies many of the issues related to that effort. The material is drawn from portions of the Agency`s Issues Paper on Radiation Site Cleanup Regulations (EPA 402-R-93-084). The site cleanup regulations will be designed to protect human health and the environment and to facilitate the cleanup of sites. EPA believes that developing specific cleanup standards for radionuclides will ensure consistent, protective, and cost-effective site remediation. They will apply to all Federal facilities such as those operated by the US Department of Energy (DOE), the US Department of Defense (DoD), and sites licensed by the US Nuclear Regulatory Commission (NRC) and its Agreement States.

Burnett, J.

1994-12-31T23:59:59.000Z

359

The orphan nuclear receptor Nur77 regulates decidual prolactin expression in human endometrial stromal cells  

SciTech Connect (OSTI)

Research highlights: {yields} Decidually produced PRL plays a key role during pregnancy. {yields} Overexpression of Nur77 increased PRL mRNA expression and enhanced decidual PRL promoter activity. {yields} Knockdown of Nur77 decreased decidual PRL secretion induced by 8-Br-cAMP and MPA. {yields} Nur77 is a novel transcription factor that plays an active role in decidual prolactin expression. -- Abstract: Prolactin (PRL) is synthesized and released by several extrapituitary tissues, including decidualized stromal cells. Despite the important role of decidual PRL during pregnancy, little is understood about the factors involved in the proper regulation of decidual PRL expression. Here we present evidence that the transcription factor Nur77 plays an active role in decidual prolactin expression in human endometrial stromal cells (hESCs). Nur77 mRNA expression in hESCs was significantly increased after decidualization stimulated by 8-Br-cAMP and medroxyprogesterone acetate (MPA). Adenovirus-mediated overexpression of Nur77 in hESCs markedly increased PRL mRNA expression and enhanced decidual PRL promoter (dPRL/-332Luc) activity in a concentration-dependent manner. Furthermore, knockdown of Nur77 in hESCs significantly decreased decidual PRL promoter activation and substantially attenuated PRL mRNA expression and PRL secretion (P < 0.01) induced by 8-Br-cAMP and MPA. These results demonstrate that Nur77 is a novel transcription factor that contributes significantly to the regulation of prolactin gene expression in human endometrial stromal cells.

Jiang, Yue; Hu, Yali; Zhao, Jing; Zhen, Xin [Reproductive Medicine Center, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008 (China)] [Reproductive Medicine Center, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008 (China); Yan, Guijun, E-mail: yanguijun33@gmail.com [Reproductive Medicine Center, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008 (China)] [Reproductive Medicine Center, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008 (China); Sun, Haixiang, E-mail: stevensunz@163.com [Reproductive Medicine Center, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008 (China)] [Reproductive Medicine Center, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008 (China)

2011-01-14T23:59:59.000Z

360

UNIVERSIDAD CENTRAL DE VENEZUELA FACULTAD DE CIENCIAS  

E-Print Network [OSTI]

sistemas li- neales y problemas de autovalores por m´etodos iterativos y para re- solver en forma num multivaluadas. 2. Ceros de funciones: M´etodo de bisecci´on. Iteraciones de punto fijo. M´etodo de Newton y de la Secante. Ceros de Polinomios. Caso multivaria- ble: m´etodo de Newton y m´etodo de Broyden. 3. C

Astudillo, Reinaldo

Note: This page contains sample records for the topic "venezuela regulation induced" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


361

El teatro de corte histórico en Venezuela  

E-Print Network [OSTI]

su proceso creador el dramaturgo necesita represen tar esos sucesos históricos para hablarle a sus contemporáneos de otras significaciones. Cabría entonces preguntarse: ¿Cuáles son las relaciones entre el teatro y la historia (entendiéndose al... partir de 1940, la renovación teatral en el país empezaba a orientarse en la búsqueda de una nueva línea de acción que supliera las limitaciones de un teatro y una dramaturgia costumbrista cuyos ingredientes más evidentes se conjugaban sin ningún tipo...

Herrera, Carlos E.

1988-04-01T23:59:59.000Z

362

Snubdrilling a new well in Venezuela  

SciTech Connect (OSTI)

A new well was successfully drilled using a snubbing jack. The drill bit was rotated using a rotary table, downhole motors and combination of the two. Expected high-pressure zones prompted this use of ``snubdrilling.`` The primary objective was to drill a vertical well through underlying sands and gain information about formation pressures. This data would aid in the drilling of a relief well using a conventional drilling rig. The secondary objective was to relieve pressure by putting this new well on production. In addition to special high-pressure drilling jobs, there are other drilling applications where snubbing jacks are a feasible alternative to conventional rotary drilling rigs or coiled tubing units. Slimhole, underbalanced and flow drilling, and sidetracking of existing wells are excellent applications for snubdrilling. Advantages of snubdrilling vs. coiled tubing drilling, include ability to rotate drillstrings, use high-torque downhole motors, pump at high rates and pressures, apply significant overpull in case of stuck pipe, and run casing and liners without rigging down. Shortcomings of drilling with snubbing jacks compared to coiled tubing are the need to stop circulation while making new connections and inability to run continuous cable inside workstrings.

Aasen, J.

1995-12-01T23:59:59.000Z

363

Universidad Central de Venezuela Facultad de Ciencias  

E-Print Network [OSTI]

#12;La Tecnología Verde, Green Computing o Green IT Algunos conceptos Huella energética (energy de la Computación Composición de Servicios Web La Tecnología Verde, Green Computing o Green tóxicos sin posibilidad de reciclaje) Green Computing o Computación Verde(informática ecológicamente

Cardinale Villarreal, Yudith C.

364

Venezuela: Energy Resources | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home5b9fcbce19 NoPublic Utilities Address: 160 East 300 South Place: Salt Lake City, Utah Zip:ScaleVegetation Jump Address: 65

365

Caracas, Venezuela: Energy Resources | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Office of Inspector GeneralDepartmentAUDIT REPORTOpenWendeGuo FengBoulder,Research JumpEnergyEnergyOpen EnergyCaracas,

366

Alternative Regulation for North American Electric Utilities  

SciTech Connect (OSTI)

After a decade of favorable operating conditions, utilities find themselves faced with accelerating prices for key inputs and a growing need for new capacity. These pressures are likely to prompt increasingly frequent, and perhaps more contentious, rate cases. Steady progress in the development of alternative regulation provides hope that the utility industry will respond to these challenges much better than in 1975-85. (author)

Lowry, Mark Newton; Kaufmann, Lawrence

2006-06-15T23:59:59.000Z

367

Policy and Regulations | Department of Energy  

Energy Savers [EERE]

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious RankCombustion |Energy UsageAUDITVehicles »ExchangeDepartment of Energy PinpointingRegulations Policy

368

Property:Regulations | Open Energy Information  

Open Energy Info (EERE)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data CenterFranconia, Virginia: EnergyPotentialUrbanUtilityScalePVCapacity Jump to: navigation,Website PropertyRegulations Property Type String

369

Rethinking Downstream Regulation: California's Opportunity to Engage Households in Reducing Greenhouse Gases  

E-Print Network [OSTI]

D. , et al. , Rethinking downstream regulation: California’sD. , et al. , Rethinking downstream regulation: California’slocate/enpol Rethinking downstream regulation: California’s

2008-01-01T23:59:59.000Z

370

Shaping the terms of competition : environmental regulation and corporate strategies to reduce diesel vehicle emissions  

E-Print Network [OSTI]

Environmental regulations are typically portrayed as an outside force stimulating development of environmental technologies in regulated industries. In reality, firms influence regulation by communicating their technological ...

Ng, Christine Bik-Kay, 1979-

2006-01-01T23:59:59.000Z

371

REVISED 3/27/01 Advanced Workshop in Regulation  

E-Print Network [OSTI]

NETWORK INDUSTRIES November 17, 2000 AUCTIONS IN NETWORK INDUSTRIES January 19, 2001 INCENTIVE REGULATION" January 19, 2001 INCENTIVE REGULATION: MAKING IT WORK Michael A. Crew (Rutgers University) and Paul R. Kleindorfer (University of Pennsylvania) "Incentive Regulation: Theory and Practice" Karl McDermot (NERA

Lin, Xiaodong

372

Hormonal regulation of microRNA expression in the ovary  

E-Print Network [OSTI]

forms of gene regulation, including post-transcriptional gene regulation. One mechanism of post-transcriptional gene regulation is the expression and function of microRNA (miRNA). These highly conserved, short, non-coding RNA molecules primarily silence...

Luense, Lacey J.

2012-12-31T23:59:59.000Z

373

Control of Wind Turbines for Power Regulation and  

E-Print Network [OSTI]

Control of Wind Turbines for Power Regulation and Load Reduction Juan Jose Garcia Quirante Kongens regulation and load reduction and their ensemble in a variable-speed wind turbine. The power regulation aspects of mathematical modelling of wind turbines, and especially the control methods suited for power

374

01.03 1 Policy & Regulation Manuals REGENTS' POLICY  

E-Print Network [OSTI]

01.03 1 Policy & Regulation Manuals REGENTS' POLICY PART I ­ MISSION AND GENERAL PROVISIONS Chapter 01.03 ­ Policy and Regulation Manuals P01.03.010. Policies and Regulations; Manuals. A. Policies by the President of the University. Adopted policies shall be maintained in the form of a Policy Manual and set out

Pantaleone, Jim

375

Coordinated Output Regulation of Multiple Heterogeneous Linear Systems  

E-Print Network [OSTI]

, the generalizations of coordination of multiple linear dynamic systems to the cooperative output regulation problemCoordinated Output Regulation of Multiple Heterogeneous Linear Systems Ziyang Meng, Tao Yang, Dimos V. Dimarogonas, and Karl H. Johansson Abstract-- The coordinated output regulation problem

Dimarogonas, Dimos

376

NOTICE OF PROPOSED REGULATION AMENDMENT Date: April 15, 2009  

E-Print Network [OSTI]

, Florida Solar Energy Center COMMENTS CONCERNING THE PROPOSED REGULATION AMENDMENT SHOULD BE SUBMITTED.: Solar Thermal and Photovoltaic System Standards UCF-8.005 and Certification SUMMARY OF REGULATION OF THE PROPOSED REGULATION AMENDMENT: UCF6C7-8.005 Solar Thermal and Photovoltaic System Standards

Wu, Shin-Tson

377

Economic Inducement Financing Program (Connecticut)  

Broader source: Energy.gov [DOE]

Companies relocating to or expanding within the state are eligible for CDA direct loans up to $5 million through its Economic Inducement Financing Program. proceeds may be used for working capital...

378

Motor regulation results in distal forces that bend partially disintegrated Chlamydomonas axonemes into circular arcs  

E-Print Network [OSTI]

The bending of cilia and flagella is driven by forces generated by dynein motor proteins. These forces slide adjacent microtubule doublets within the axoneme, the motile cytoskeletal structure. To create regular, oscilla- tory beating patterns, the activities of the axonemal dyneins must be coordinated both spatially and temporally. It is thought that coordination is mediated by stresses or strains, which build up within the moving axoneme, and somehow regulate dynein activity. While experimenting with axonemes subjected to mild proteolysis, we observed pairs of doublets associate with each other and form bends with almost constant curvature. By model- ing the statics of a pair of filaments, we show that the activity of the motors concentrates at the distal tips of the doublets. Furthermore, we show that this distribution of motor activity accords with models in which curvature, or curvature-induced normal forces, regulates the activity of the motors. These observations, together with our theoretical analysis, provide evidence that dynein activity can be regulated by curvature or normal forces, which may, therefore, play a role in coordinating the beating of cilia and flagella.

V. Mukundan; P. Sartori; V. F. Geyer; F. Julicher; J. Howard

2014-04-08T23:59:59.000Z

379

Positive feedback and temperature mediated molecular switch controls differential gene regulation in Bordetella pertussis  

E-Print Network [OSTI]

Based on the phosphorelay kinetics operative within BvgAS two component system we propose a mathematical framework for signal transduction and gene regulation of phenotypic phases in Bordetella pertussis. The proposed model identifies a novel mechanism of transcriptional interference between two promoters present in the bvg locus. To understand the system behavior under elevated temperature, the developed model has been studied in two different ways. First, a quasi-steady state analysis has been carried out for the two component system, comprising of sensor BvgS and response regulator BvgA. The quasi-steady state analysis reveals temperature induced sharp molecular switch, leading to amplification in the output of BvgA. Accumulation of a large pool of BvgA thus results into differential regulation of the downstream genes, including the gene encoding toxin. Numerical integration of the full network kinetics is then carried out to explore time dependent behavior of different system components, that qualitatively capture the essential features of experimental results performed in vivo. Furthermore, the developed model has been utilized to study mutants that are impaired in their ability to phosphorylate the transcription factor, BvgA, of the signaling network.

Arnab Bandyopadhyay; Suman K. Banik

2012-08-17T23:59:59.000Z

380

Regulation of mammary gland remodelling and lactation  

E-Print Network [OSTI]

and their expression, organization and physico-chemical properties of casein micelle, and subcellular transport not induce any insulin resistance, but it improves the insulin- stimulated glucose disposal in lactating presented: laser scanning cytometry for mammary apoptosis research, septaplex PCR for "parent- age control

Paris-Sud XI, Université de

Note: This page contains sample records for the topic "venezuela regulation induced" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


381

INPP4B-mediated tumor resistance is associated with modulation of glucose metabolism via hexokinase 2 regulation in laryngeal cancer cells  

SciTech Connect (OSTI)

Highlights: •HIF-1?-regulated INPP4B enhances glycolysis. •INPP4B regulates aerobic glycolysis by inducing HK2 via Akt-mTOR pathway. •Blockage of INPP4B and HK2 sensitizes radioresistant laryngeal cancer cells to radiation and anticancer drug. •INPP4B is associated with HK2 in human laryngeal cancer tissues. -- Abstract: Inositol polyphosphate 4-phosphatase type II (INPP4B) was recently identified as a tumor resistance factor in laryngeal cancer cells. Herein, we show that INPP4B-mediated resistance is associated with increased glycolytic phenotype. INPP4B expression was induced by hypoxia and irradiation. Intriguingly, overexpression of INPP4B enhanced aerobic glycolysis. Of the glycolysis-regulatory genes, hexokinase 2 (HK2) was mainly regulated by INPP4B and this regulation was mediated through the Akt-mTOR pathway. Notably, codepletion of INPP4B and HK2 markedly sensitized radioresistant laryngeal cancer cells to irradiation or anticancer drug. Moreover, INPP4B was significantly associated with HK2 in human laryngeal cancer tissues. Therefore, these results suggest that INPP4B modulates aerobic glycolysis via HK2 regulation in radioresistant laryngeal cancer cells.

Min, Joong Won [Division of Radiation Cancer Research, Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of)] [Division of Radiation Cancer Research, Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of); Kim, Kwang Il [Molecular Imaging Research Center, Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of)] [Molecular Imaging Research Center, Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of); Kim, Hyun-Ah; Kim, Eun-Kyu; Noh, Woo Chul [Department of Surgery, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of)] [Department of Surgery, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of); Jeon, Hong Bae [Biomedical Research Institute, MEDIPOST Co., Ltd., Seoul (Korea, Republic of)] [Biomedical Research Institute, MEDIPOST Co., Ltd., Seoul (Korea, Republic of); Cho, Dong-Hyung [Graduate School of East-West Medical Science, Kyung Hee University, Gyeonggi-do (Korea, Republic of)] [Graduate School of East-West Medical Science, Kyung Hee University, Gyeonggi-do (Korea, Republic of); Oh, Jeong Su [Department of Genetic Engineering, Sungkyunkwan University, Suwon (Korea, Republic of)] [Department of Genetic Engineering, Sungkyunkwan University, Suwon (Korea, Republic of); Park, In-Chul; Hwang, Sang-Gu [Division of Radiation Cancer Research, Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of)] [Division of Radiation Cancer Research, Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of); Kim, Jae-Sung, E-mail: jaesung@kirams.re.kr [Division of Radiation Cancer Research, Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of)] [Division of Radiation Cancer Research, Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of)

2013-10-11T23:59:59.000Z

382

Evolving Role of the Power Sector Regulator: A Clean Energy Regulators Initiative Report  

SciTech Connect (OSTI)

This paper seeks to briefly characterize the evolving role of power sector regulation. Given current global dynamics, regulation of the power sector is undergoing dramatic changes. This transformation is being driven by various factors including technological advances and cost reductions in renewable energy, energy efficiency, and demand management; increasing air pollution and climate change concerns; and persistent pressure for ensuring sustainable economic development and increased access to energy services by the poor. These issues add to the already complex task of power sector regulation, of which the fundamental remit remains to objectively and transparently ensure least-cost service delivery at high quality. While no single regulatory task is trivial to undertake, it is the prioritization and harmonization of a multitude of objectives that exemplifies the essential challenge of power sector regulation. Evolving regulatory roles can be understood through the concept of existing objectives and an additional layer of emerging objectives. Following this categorization, we describe seven existing objectives of power sector regulators and nine emerging objectives, highlighting key challenges and outlining interdependencies. This essay serves as a preliminary installment in the Clean Energy Regulatory Initiative (CERI) series, and aims to lay the groundwork for subsequent reports and case studies that will explore these topics in more depth.

Zinaman, O.; Miller, M.; Bazilian, M.

2014-04-01T23:59:59.000Z

383

PES1 regulates sensitivity of colorectal cancer cells to anticancer drugs  

SciTech Connect (OSTI)

Highlights: ? PES1 was overexpressed in diverse cancer cell lines. ? PES1-ablation enhances DNA damage response by decreasing DNA repair. ? PES1-ablation increases the sensitivity of HCT116 cells to chemotherapeutic agents. ? PES1-ablation is associated with diminished nuclear entry of RAD51. -- Abstract: PES1 (also known as Pescadillo), a nucleolar protein, was involved in biogenesis of ribosomal RNA. Up-regulation of PES1 has been documented in some human cancers, indicating that PES1 may play some crucial roles in tumorigenesis. In our previous study, it was found that silencing of PES1 resulted in decreased proliferation of colorectal cancer cells. We also noticed that depletion of PES1 altered expression profiles of diverse genes. In the present study, we validated the expression changes of a subset of genotoxic stress-related genes in PES1-silenced HCT116 cells by quantitative RT-PCR. The steady and etoposide-induced phosphorylated H2AX (?-H2AX) were higher in PES1-silenced cells than in control cells. Besides, etoposide-induced ?-H2AX persisted longer in PES1-silenced cells after removing the etoposide. Next, results of comet assay revealed decreased DNA repair after PES1-ablation. PES1-ablated cells were more sensitive to chemotherapeutic agents, which could be reversed by reconstitution with exogenous PES1. Furthermore, deletion of PES1 diminished steady and DNA damage-induced levels of nuclear RAD51. Our results uncover a potential role of PES1 in chemoresistance by regulating DNA damage response in colorectal cancer cells.

Xie, Wei [Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Biochemistry and Molecular Biology, Peking University Cancer Hospital and Institute, Beijing 100142 (China)] [Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Biochemistry and Molecular Biology, Peking University Cancer Hospital and Institute, Beijing 100142 (China); Qu, Like, E-mail: qulike@bjcancer.org [Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Biochemistry and Molecular Biology, Peking University Cancer Hospital and Institute, Beijing 100142 (China)] [Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Biochemistry and Molecular Biology, Peking University Cancer Hospital and Institute, Beijing 100142 (China); Meng, Lin; Liu, Caiyun; Wu, Jian [Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Biochemistry and Molecular Biology, Peking University Cancer Hospital and Institute, Beijing 100142 (China)] [Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Biochemistry and Molecular Biology, Peking University Cancer Hospital and Institute, Beijing 100142 (China); Shou, Chengchao, E-mail: scc@bjcancer.org [Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Biochemistry and Molecular Biology, Peking University Cancer Hospital and Institute, Beijing 100142 (China)] [Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Biochemistry and Molecular Biology, Peking University Cancer Hospital and Institute, Beijing 100142 (China)

2013-02-15T23:59:59.000Z

384

Self-regulated gravitational accretion in protostellar discs  

E-Print Network [OSTI]

We present a numerical model for the evolution of a protostellar disc that has formed self-consistently from the collapse of a molecular cloud core. The global evolution of the disc is followed for several million years after its formation. The capture of a wide range of spatial and temporal scales is made possible by use of the thin-disc approximation. We focus on the role of gravitational torques in transporting mass inward and angular momentum outward during different evolutionary phases of a protostellar disc with disc-to-star mass ratio of order 0.1. In the early phase, when the infall of matter from the surrounding envelope is substantial, mass is transported inward by the gravitational torques from spiral arms that are a manifestation of the envelope-induced gravitational instability in the disc. In the late phase, when the gas reservoir of the envelope is depleted, the distinct spiral structure is replaced by ongoing irregular nonaxisymmetric density perturbations. The amplitude of these density perturbations decreases with time, though this process is moderated by swing amplification aided by the existence of the disc's sharp outer edge. Our global modelling of the protostellar disc reveals that there is typically a residual nonzero gravitational torque from these density perturbations, i.e. their effects do not exactly cancel out in each region. In particular, the net gravitational torque in the inner disc tends to be negative during first several million years of the evolution, while the outer disc has a net positive gravitational torque. Our global model of a self-consistently formed disc shows that it is also self-regulated in the late phase, so that it is near the Toomre stability limit, with a near-uniform Toomre parameter Q\\approx 1.5-2.0. (Abstract abridged).

E. I. Vorobyov; S. Basu

2007-09-13T23:59:59.000Z

385

Self-regulating flow control device  

DOE Patents [OSTI]

A variable, self-regulating valve having a hydraulic loss coefficient proportional to a positive exponential power of the flow rate. The device includes two objects in a flow channel and structure which assures that the distance between the two objects is an increasing function of the flow rate. The range of spacing between the objects is such that the hydraulic resistance of the valve is an increasing function of the distance between the two objects so that the desired hydraulic loss coefficient as a function of flow rate is obtained without variation in the flow area.

Humphreys, Duane A. (Pittsburgh, PA)

1984-01-01T23:59:59.000Z

386

International Electricity Regulation | Department of Energy  

Office of Environmental Management (EM)

AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE:1 First Use of Energy for All Purposes (Fuel and Nonfuel),Feet) Year Jan Feb Mar Apr May Jun Jul(Summary) " ,"ClickPipelinesProvedDecemberInitiatives Initiatives Through a varietyInternationalRegulation

387

Environmental Regulation Impacts on Eastern Interconnection Performance  

SciTech Connect (OSTI)

In the United States, recent environmental regulations will likely result in the removal of nearly 30 GW of oil and coal-fired generation from the power grid, mostly in the Eastern Interconnection (EI). The effects of this transition on voltage stability and transmission line flows have previously not been studied from a system-wide perspective. This report discusses the results of power flow studies designed to simulate the evolution of the EI over the next few years as traditional generation sources are replaced with environmentally friendlier ones such as natural gas and wind.

Markham, Penn N [ORNL; Liu, Yilu [ORNL; Young II, Marcus Aaron [ORNL

2013-07-01T23:59:59.000Z

388

Nickel-regulated heart rate variability: The roles of oxidative stress and inflammation  

SciTech Connect (OSTI)

Heart rate variability (HRV) has been reported to be a putative marker of cardiac autonomic imbalance caused by exposure to ambient particulate matter (PM). Our objective in this study was to determine the effects on HRV from exposure to nickel, an important chemical component of ambient PM that results in oxidative stress and inflammation. HRV data were collected for 72 h before lung exposure (baseline) and 72 h after intratracheal exposure (response) to nickel sulphate (NiSO{sub 4}; 526 ?g) in Wistar Kyoto (WKY) and spontaneously hypertensive (SH) rats. The antioxidant N-acetyl-L-cysteine (NAC) and the anti-inflammatory celecoxib were intraperitoneally injected to examine post-exposure oxidative and inflammatory responses. Self-controlled experiments examined the effects of NiSO{sub 4} exposure on average normal-to-normal intervals (ANN), natural logarithm-transformed standard deviation of the normal-to-normal intervals (LnSDNN) and root mean square of successive differences of adjacent normal-to-normal intervals (LnRMSSD); the resulting data were sequentially analysed using the generalised estimating equation model. HRV effects on NiSO{sub 4}-exposed SH rats were greater than those on NiSO{sub 4}-exposed WKY rats. After adjusted the HRV responses in the WKY rats as control, ANN and LnRMSSD were found to be quadratically increased over 72 h after exposure to NiSO{sub 4}. Both NAC and celecoxib mitigated the NiSO{sub 4}-induced alterations in HRV during the exposure period. The results suggest that concurrent Ni-induced oxidative stress and inflammatory responses play important roles in regulating HRV. These findings help bridge the gap between epidemiological and clinical studies on the plausible mechanisms of the cardiovascular consequences induced by chemical components in ambient PM. -- Highlights: ? To determine the effects on HRV from exposure to nickel. ? ANN and LnRMSSD were found to be quadratically increased after exposure to Ni. ? NAC and celecoxib mitigated the Ni-induced alterations in HRV. ? Ni-induced oxidative stress and inflammation play the roles in regulating HRV.

Chuang, Hsiao-Chi, E-mail: r92841005@ntu.edu.tw [School of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei, Taiwan (China) [School of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei, Taiwan (China); Division of Pulmonary Medicine, Department of Internal Medicine, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan (China); Hsueh, Tzu-Wei, E-mail: r95841015@ntu.edu.tw [Institute of Occupational Medicine and Industrial Hygiene, Department of Public Health, National Taiwan University, Taipei, Taiwan (China)] [Institute of Occupational Medicine and Industrial Hygiene, Department of Public Health, National Taiwan University, Taipei, Taiwan (China); Chang, Chuen-Chau, E-mail: nekota@tmu.edu.tw [Department of Anaesthesiology, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan (China)] [Department of Anaesthesiology, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan (China); Hwang, Jing-Shiang, E-mail: jshwang@stat.sinica.edu.tw [Institute of Statistical Science, Academia Sinica, Taipei, Taiwan (China)] [Institute of Statistical Science, Academia Sinica, Taipei, Taiwan (China); Chuang, Kai-Jen, E-mail: kjc@tmu.edu.tw [Department of Public Health, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan (China) [Department of Public Health, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan (China); School of Public Health, College of Public Health and Nutrition, Taipei Medical University, Taipei, Taiwan (China); Yan, Yuan-Horng, E-mail: d97841006@ntu.edu.tw [Institute of Occupational Medicine and Industrial Hygiene, Department of Public Health, National Taiwan University, Taipei, Taiwan (China) [Institute of Occupational Medicine and Industrial Hygiene, Department of Public Health, National Taiwan University, Taipei, Taiwan (China); Department of Medical Research, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chiayi City, Taiwan (China); Cheng, Tsun-Jen, E-mail: tcheng@ntu.edu.tw [Institute of Occupational Medicine and Industrial Hygiene, Department of Public Health, National Taiwan University, Taipei, Taiwan (China) [Institute of Occupational Medicine and Industrial Hygiene, Department of Public Health, National Taiwan University, Taipei, Taiwan (China); Department of Public Health, College of Public Health, National Taiwan University, Taipei, Taiwan (China)

2013-01-15T23:59:59.000Z

389

Review: Endocrine regulation of placental phenotype  

E-Print Network [OSTI]

substrate uptake during increased ovine fetal cortisol concentration. 682 Am J Physiol 1996; 271:E186-E191. 683 102 Timmerman M, Teng C, Wilkening RB, Fennessey P, Battaglia FC, Meschia G. Effect of 684 dexamethasone on fetal hepatic glutamine... -glutamate exchange. Am J Physiol 2000; 685 278: E839-E845. 686 103 Barbera A, Wilkening RB, Teng C, Battaglia FC, Meschia G. Metabolic alterations in the 687 fetal hepatic and umbilical circulations during glucocorticoid-induced parturition in 688 sheep. Pediatr...

Fowden, A.L.; Forhead, A.J.; Sferruzzi-Perri, A.N.; Burton, G.J.; Vaughan, O.R.

2014-12-03T23:59:59.000Z

390

Quantifying the relative importance of flow regulation and grain size regulation of suspended sediment transport and  

E-Print Network [OSTI]

sediment transport and tracking changes in grain size of bed sediment David M. Rubin U.S. Geological Survey changes in sediment transport, it is essential to know whether transport is regulated mainly by changes in flow or by changes in grain size of sediment on the bed. In flows where changes in suspended sediment

391

Regulation of indoor air quality: The last frontier of environmental regulation  

SciTech Connect (OSTI)

Indoor air pollution (IAP) is ranked by the Environmental Protection Agency (EPA) among the top five environmental risks to human health. The World Health Organization estimates that nearly one in every six commercial buildings in the United States suffers from sick-building syndrome and that occupants of another one in twelve suffer from building-related illnesses. Indoor air quality (IAQ) problems cost American business $10 billion per year through lowered productivity, absenteeism, and medical costs. Yet despite the importance and high cost of IAQ problems, indoor air is not yet specifically addressed in any federal regulatory program. The reason probably is because indoor air is a quanitatively different environment in which traditional modes of regulation, based on pollutant-by pollutant risk assessments, are of limited utility. This paper covers the following topics: four factors influencing IAQ regulation; EPA regulation of indoor air; the role of the consumer product safety commission; OSHA and IAQ issues; state regulation and economic concerns; the pressure for legislation.

Dickson, R.B. [Paul, Hastings, Janofsky & Walker, Washington, DC (United States)

1994-12-31T23:59:59.000Z

392

University Computing Regulations The University of Edinburgh has adopted a set of Regulations to cover the  

E-Print Network [OSTI]

applicable to investigating breaches or suspected breaches are in Regulation 6 below. 2. Private education. All other use is private. Private use is allowed, as a privilege and not a right, but if abused. Damage of computing facilities No person shall, unless appropriately authorised, take any action which

Koehn, Philipp

393

Graphene with geometrically induced vorticity  

E-Print Network [OSTI]

At half filling, the electronic structure of graphene can be modelled by a pair of free two-dimensional Dirac fermions. We explicitly demonstrate that in the presence of a geometrically induced gauge field, an everywhere-real Kekule modulation of the hopping matrix elements can correspond to a non-real Higgs field with non-trivial vorticity. This provides a natural setting for fractionally charged vortices with localized zero modes. For fullerene-like molecules we employ the index theorem to demonstrate the existence of six low-lying states that do not depend strongly on the Kekule-induced mass gap.

Jiannis K. Pachos; Michael Stone; Kristan Temme

2008-03-26T23:59:59.000Z

394

Glycogen synthase kinase 3 regulates PAX3-FKHR-mediated cell proliferation in human alveolar rhabdomyosarcoma cells  

SciTech Connect (OSTI)

Patients with alveolar rhabdomyosarcoma (ARMS) have poorer response to conventional chemotherapy and lower survival rates than those with embryonal RMS (ERMS). To identify compounds that preferentially block the growth of ARMS, we conducted a small-scale screen of 160 kinase inhibitors against the ARMS cell line Rh30 and ERMS cell line RD and identified inhibitors of glycogen synthase kinase 3 (GSK3), including TWS119 as ARMS-selective inhibitors. GSK3 inhibitors inhibited cell proliferation and induced apoptosis more effectively in Rh30 than RD cells. Ectopic expression of fusion protein PAX3-FKHR in RD cells significantly increased their sensitivity to TWS119. Down-regulation of GSK3 by GSK3 inhibitors or siRNA significantly reduced the transcriptional activity of PAX3-FKHR. These results suggest that GSK3 is directly involved in regulating the transcriptional activity of PAX3-FKHR. Also, GSK3 phosphorylated PAX3-FKHR in vitro, suggesting that GSK3 might regulate PAX3-FKHR activity via phosphorylation. These findings support a novel mechanism of PAX3-FKHR regulation by GSK3 and provide a novel strategy to develop GSK inhibitors as anti-ARMS therapies.

Zeng, Fu-Yue; Dong, Hanqing; Cui, Jimmy; Liu, Lingling [Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105 (United States)] [Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105 (United States); Chen, Taosheng, E-mail: taosheng.chen@stjude.org [Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105 (United States)] [Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105 (United States)

2010-01-01T23:59:59.000Z

395

Title of Thesis: COMPARING MICROWAVE INDUCED POLYMERIZATION TO THERMAL INDUCED POLYMERIZATION OF THE  

E-Print Network [OSTI]

ABSTRACT Title of Thesis: COMPARING MICROWAVE INDUCED POLYMERIZATION TO THERMAL INDUCED POLYMERIZATION OF THE RESIN BISPHENOL A-GLYCIDYL METHACRYLATE. Degree candidate: Thomas J. Miller Degree and year Engineering This thesis presents a theoretical and experimental comparison of polymerization induced

Anlage, Steven

396

Regulating forest practices in Texas: a problem analysis  

E-Print Network [OSTI]

REGULATING FOREST PRACTICES IN TEXAS: A PROBLEM ANALYSIS A Thesis by ALAN DALE DREESEN Submitted to the Graduate College of Texas A&M University in partial fulfillment of the requirement for the degree of MASTER OF SCIENCE August 1977 Ma...]or Subject: Forestry REGULATING FOREST PRACTICES IN TEXAS: A PROBLEM ANALYSIS A Thesis by ALAN DALE DREESEN Approved as to style and content by: (Chair of Committee) ( ead of Depa t nt) (Member) (Member) August 1977 ABSTRACT Regulating Forest...

Dreesen, Alan D

1977-01-01T23:59:59.000Z

397

Radiation Induced Instability Patrick Hagerty  

E-Print Network [OSTI]

Radiation Induced Instability Patrick Hagerty #3; Department of Mathematics University of Michigan of Michigan Ann Arbor, MI 48109 abloch@math.lsa.umich.edu Michael I. Weinstein z Fundamental Mathematics a central rigid body which can radiate energy through exible components such as solar panels and antennae

Bloch, Anthony

398

Induced geometry from disformal transformation  

E-Print Network [OSTI]

In this note, we use the disformal transformation to induce a geometry from the manifold which is originally Riemannian. The new geometry obtained here can be considered as a generalization of Weyl integrable geometry. Based on these results, we further propose a geometry which is naturally a generalization of Weyl geometry.

Yuan, Fang-Fang

2015-01-01T23:59:59.000Z

399

Induced geometry from disformal transformation  

E-Print Network [OSTI]

In this note, we use the disformal transformation to induce a geometry from the manifold which is originally Riemannian. The new geometry obtained here can be considered as a generalization of Weyl integrable geometry. Based on these results, we further propose a geometry which is naturally a generalization of Weyl geometry.

Fang-Fang Yuan; Peng Huang

2015-02-08T23:59:59.000Z

400

Regulation of Gas, Electric, and Water Companies (Maryland)  

Broader source: Energy.gov [DOE]

The Public Service Commission is responsible for regulating gas, electric, and water companies in the state. This legislation contains provisions for such companies, addressing planning and siting...

Note: This page contains sample records for the topic "venezuela regulation induced" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


401

Hazardous and Nonhazardous Solid Waste Applicant Disclosure Regulations (Mississippi)  

Broader source: Energy.gov [DOE]

The purpose of the Hazardous and Nonhazardous Solid Waste Applicant Disclosure Regulations is to help maintain accountability and track data on the hazardous and nonhazardous waste sites in...

402

Biomass Boiler and Furnace Emissions and Safety Regulations in...  

Open Energy Info (EERE)

Biomass Boiler and Furnace Emissions and Safety Regulations in the Northeast States Jump to: navigation, search Tool Summary LAUNCH TOOL Name: Biomass Boiler and Furnace Emissions...

403

National Energy Board Export and Import Reporting Regulations (Canada)  

Broader source: Energy.gov [DOE]

These regulations of the Canadian National Energy Board are for the administration of importing and exporting energy, including natural gas and electricity.

404

Air Pollution Control Regulations: No.27 - Control of Nitrogen...  

Broader source: Energy.gov (indexed) [DOE]

Commercial Industrial Investor-Owned Utility MunicipalPublic Utility Rural Electric Cooperative Utility Program Info State Rhode Island Program Type Environmental Regulations...

405

Air Pollution Control Regulations: No. 7 - Emission of Air Contaminant...  

Broader source: Energy.gov (indexed) [DOE]

with the enjoyment of life and property. The criteria for determining compliance is listed in the regulations, and is based on other air pollution and ambient air standards...

406

Air Pollution Control Regulations: No. 6 - Continuous Emissions...  

Broader source: Energy.gov (indexed) [DOE]

Commercial Industrial Investor-Owned Utility MunicipalPublic Utility Rural Electric Cooperative Utility Program Info State Rhode Island Program Type Environmental Regulations...

407

UNIDO-Training Program on Sustainable Energy Regulation and Policymaki...  

Open Energy Info (EERE)

The main focuses of the training package are the energy regulation and power sector reform, the increased renewable energy technology penetration for rural electrification as...

408

Distribution System Voltage Regulation by Distributed Energy Resources  

SciTech Connect (OSTI)

This paper proposes a control method to regulate voltages in 3 phase unbalanced electrical distribution systems. A constrained optimization problem to minimize voltage deviations and maximize distributed energy resource (DER) active power output is solved by harmony search algorithm. IEEE 13 Bus Distribution Test System was modified to test three different cases: a) only voltage regulator controlled system b) only DER controlled system and c) both voltage regulator and DER controlled system. The simulation results show that systems with both voltage regulators and DER control provide better voltage profile.

Ceylan, Oguzhan [ORNL; Liu, Guodong [ORNL; Xu, Yan [ORNL; Tomsovic, Kevin [University of Tennessee, Knoxville (UTK)

2014-01-01T23:59:59.000Z

409

Regulation of Zinc Transport in the Choroid Plexus  

E-Print Network [OSTI]

expression by prolactin. These data indicate there is a coordinated regulation of MT-1 and zinc transporters during extracellular zinc depletion or supplementation....

Aquino, Mayra

2014-07-21T23:59:59.000Z

410

The regulation of internet interconnection : assessing network market power  

E-Print Network [OSTI]

Interconnection agreements in the telecommunications industry have always been constrained by regulation. Internet interconnection has not received the same level of scrutiny. Recent debates regarding proposed mergers, ...

Maida, Elisabeth M. (Elisabeth Marigo)

2013-01-01T23:59:59.000Z

411

Council on Environmental Quality (CEQ) NEPA Regulations: 40 CFR...  

Open Energy Info (EERE)

to library Legal Document- Secondary Legal SourceSecondary Legal Source: Council on Environmental Quality (CEQ) NEPA Regulations: 40 CFR 1500 - 1518Legal Author CEQ Published NA...

412

Natural Gas Regulation- Delaware Public Service Commission (Delaware)  

Broader source: Energy.gov [DOE]

The Delaware Public Service Commission regulates only the distribution of natural gas to Delaware consumers. The delivery and administrative costs associated with natural gas distribution are...

413

Regulated Emissions from Diesel and Compressed Natural Gas Transit...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

Emissions from Diesel and Compressed Natural Gas Transit Buses Regulated Emissions from Diesel and Compressed Natural Gas Transit Buses Poster presentaiton at the 2007 Diesel...

414

Providing Minute-to-Minute Regulation from Wind Plants: Preprint  

SciTech Connect (OSTI)

In this paper, we extend the previous analysis using time series data from existing wind plants, system loads, and regulation and energy markets.

Kirby, B.; Milligan, M.; Ela, E.

2010-10-01T23:59:59.000Z

415

Rules and Regulations Pertaining to the Management of Wastes (Nebraska)  

Broader source: Energy.gov [DOE]

These regulations, promulgated by the Department of Environmental Quality, contain provisions pertaining to waste management permits and licenses, wastewater, and the release of hazardous substances.

416

administration regulations based: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

regulation when damages vary across sources: What are the gains from differentiation? Power Transmission, Distribution and Plants Websites Summary: For much of the air pollution...

417

Electricity Merger Policy in the Shadow of Regulation  

E-Print Network [OSTI]

Caps to ?! #? #!? ,” The Electricity Journal, vol. 14, May,Analysis of the New Jersey Electricity Market ” New Jersey2005), “Regulating the Electricity Supply Industry in

Gilbert, Richard J; Newberry, David M

2006-01-01T23:59:59.000Z

418

Goodyear's Self-Regulating Tires Save Fuel, Improve Safety, Win...  

Energy Savers [EERE]

on the environment. Addthis Related Articles This graphic shows how Goodyear's new Air Maintenance Technology -- also called the self-regulating tire -- works. | Graphic...

419

Evolutionary-Economic Principles as Regulators of Soil Enzyme Production  

E-Print Network [OSTI]

Chapter 12 Evolutionary-Economic Principles as Regulators of Soil Enzyme Production and Ecosystem (chitinases), organic phosphates (phosphatases), and lignins (oxidases, peroxidases) (Burns 1978; Allison et

German, Donovan P.

420

Transport Regulation from Theory to Practice: General Observations...  

Open Energy Info (EERE)

and a Case Study Jump to: navigation, search Tool Summary LAUNCH TOOL Name: Transport Regulation from Theory to Practice: General Observations and a Case Study Agency...

Note: This page contains sample records for the topic "venezuela regulation induced" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


421

Guide to Federal Regulation of Sales of Imported Electricity...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

use of energy. Introduction This Guide to Federal Regulation of Sales of Imported Electricity in Canada, Mexico, and the United States is intended to inform national energy...

422

Code of Federal Regulations PART 835-OCCUPATIONAL RADIATION PROTECTION...  

Office of Environmental Management (EM)

& Publications Code of Federal Regulations OCCUPATIONAL RADIATION PROTECTION An Engine Exhaust Particle SizerTM Spectrometer for Transient Emission Particle Measurements...

423

50 CFR 216 - Regulations Governing the Taking and Importing of...  

Open Energy Info (EERE)

Mammals (2014). Retrieved from "http:en.openei.orgwindex.php?title50CFR216-RegulationsGoverningtheTakingandImportingofMarineMammals&oldid790887" Categories:...

424

Comments Received on Proposed Rulemaking for regulation implementing...  

Broader source: Energy.gov (indexed) [DOE]

DOE published a Notice of Proposed Rulemaking for regulation implementing section 216(h). Comments on the proposed rule were originally due on January 27, 2012. The comment...

425

Protocadherin-7 induces bone metastasis of breast cancer  

SciTech Connect (OSTI)

Highlights: •PCDH7 is overexpression in high bone metastatic MDA-MB-231 cells. •PCDH7 is up-regulation in bone metastatic breast cancer tissues. •Suppression of PCDH7 inhibits cell proliferation, migration, and invasion in vitro. •PCDH7 induces breast cancer bone metastasis in vivo. -- Abstract: Breast cancer had a propensity to metastasize to bone, resulting in serious skeletal complications associated with poor outcome. Previous study showed that Protocadherin-7 (PCDH7) play an important role in brain metastatic breast cancer, however, the role of PCDH7 in bone metastatic breast cancer has never been explored. In the present study, we found that PCDH7 expression was up-regulation in bone metastatic breast cancer tissues by real-time PCR and immunohistochemistry assays. Furthermore, suppression of PCDH7 inhibits breast cancer cell proliferation, migration, and invasion in vitro by MTT, scratch, and transwell assays. Most importantly, overexpression of PCDH7 promotes breast cancer cell proliferation and invasion in vitro, and formation of bone metastasis in vivo. These data provide an important insight into the role of PCDH7 in bone metastasis of breast cancer.

Li, Ai-Min [Department of Orthopedics, The 5th Central Hospital of Tianjin, Tianjin (China)] [Department of Orthopedics, The 5th Central Hospital of Tianjin, Tianjin (China); Tian, Ai-Xian [Department of Biochemistry and Molecular Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China)] [Department of Biochemistry and Molecular Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China); Zhang, Rui-Xue [Department of Clinical Laboratory Diagnosis, Tianjin Medical University, Tianjin (China)] [Department of Clinical Laboratory Diagnosis, Tianjin Medical University, Tianjin (China); Ge, Jie [Department of Breast Surgery, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China) [Department of Breast Surgery, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China); Key Laboratory of Breast Cancer Prevention and Treatment of the Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China); Sun, Xuan [Department of Breast Surgery, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China)] [Department of Breast Surgery, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China); Cao, Xu-Chen, E-mail: caoxuch@126.com [Department of Breast Surgery, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China) [Department of Breast Surgery, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China); Key Laboratory of Breast Cancer Prevention and Treatment of the Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin (China)

2013-07-05T23:59:59.000Z

426

Bending-induced Symmetry Breaking of Lithiation in Germanium Nanowires  

SciTech Connect (OSTI)

From signal transduction of living cells to oxidation and corrosion of metals, mechanical stress intimately couples with chemical reactions, regulating these biological and physiochemical processes. The coupled effect is particularly evident in electrochemical lithiation/delithiation cycling of high-capacity electrodes, such as silicon (Si), where on one hand lithiation-generated stress mediates lithiation kinetics, and on the other electrochemical reaction rate regulates stress generation and mechanical failure of the electrodes. Here we report for the first time the evidence on the controlled lithiation in germanium nanowires (GeNWs) through external bending. Contrary to the symmetric core-shell lithiation in free-standing GeNWs, we show bending GeNWs breaks the lithiation symmetry, speeding up lithaition at the tensile side while slowing down at the compressive side of the GeNWs. The bending-induced symmetry breaking of lithiation in GeNWs is further corroborated by chemomechanical modeling. In the light of the coupled effect between lithiation kinetics and mechanical stress in the electrochemical cycling, our findings shed light on strain/stress engineering of durable high-rate electrodes and energy harvesting through mechanical motion.

Gu, Meng; Yang, Hui; Perea, Daniel E.; Zhang, Jiguang; Zhang, Sulin; Wang, Chong M.

2014-08-01T23:59:59.000Z

427

System and method for regulating resonant inverters  

DOE Patents [OSTI]

A technique is provided for direct digital phase control of resonant inverters based on sensing of one or more parameters of the resonant inverter. The resonant inverter control system includes a switching circuit for applying power signals to the resonant inverter and a sensor for sensing one or more parameters of the resonant inverter. The one or more parameters are representative of a phase angle. The resonant inverter control system also includes a comparator for comparing the one or more parameters to a reference value and a digital controller for determining timing of the one or more parameters and for regulating operation of the switching circuit based upon the timing of the one or more parameters.

Stevanovic, Ljubisa Dragoljub (Clifton Park, NY); Zane, Regan Andrew (Superior, CO)

2007-08-28T23:59:59.000Z

428

Economics and regulation of petroleum futures markets  

SciTech Connect (OSTI)

Because the futures market in petroleum products is a relatively recent phenomenon, the implications of public policies formulated for that market have not yet been fully explored. To provide the Office of Competition of the Department of Energy (DOE) with sufficient information to assess policy alternatives, Resource Planning Associates, Inc. (RPA) was asked to analyze the development of the futures market in No. 2 oil, assess the potential for futures markets in other petroleum products, and identify policy alternatives available to DOE. To perform this analysis, the criteria for a viable futures market was established first. Then, the experience to date with the 18-month-old futures market in No. 2 oil was examined, and the potential for viable futures markets in No. 6 oil, gasoline, jet fuel, and crude oil was assessed. Finally, how existing DOE regulations and prospective actions might affect petroleum futures market development was investigated.

Not Available

1980-08-01T23:59:59.000Z

429

Coherent regulation in yeast cell cycle network  

E-Print Network [OSTI]

We define a measure of coherent activity for gene regulatory networks, a property that reflects the unity of purpose between the regulatory agents with a common target. We propose that such harmonious regulatory action is desirable under a demand for energy efficiency and may be selected for under evolutionary pressures. We consider two recent models of the cell-cycle regulatory network of the budding yeast, Saccharomyces cerevisiae, as a case study and calculate their degree of coherence. A comparison with random networks of similar size and composition reveals that the yeast's cell-cycle regulation is wired to yield and exceptionally high level of coherent regulatory activity. We also investigate the mean degree of coherence as a function of the network size, connectivity and the fraction of repressory/activatory interactions.

Nese Aral; Alkan Kabakcioglu

2014-12-14T23:59:59.000Z

430

Incentive regulation of investor-owned nuclear power plants by public utility regulators. Revision 1  

SciTech Connect (OSTI)

The US Nuclear Regulatory Commission (NRC) periodically surveys the Federal Energy Regulatory Commission (FERC) and state regulatory commissions that regulate utility owners of nuclear power plants. The NRC is interested in identifying states that have established economic or performance incentive programs applicable to nuclear power plants, how the programs are being implemented, and in determining the financial impact of the programs on the utilities. The NRC interest stems from the fact that such programs have the potential to adversely affect the safety of nuclear power plants. The current report is an update of NUREG/CR-5975, Incentive Regulation of Investor-Owned Nuclear Power Plants by Public Utility Regulators, published in January 1993. The information in this report was obtained from interviews conducted with each state regulatory agency that administers an incentive program and each utility that owns at least 10% of an affected nuclear power plant. The agreements, orders, and settlements that form the basis for each incentive program were reviewed as required. The interviews and supporting documentation form the basis for the individual state reports describing the structure and financial impact of each incentive program.

McKinney, M.D.; Seely, H.E.; Merritt, C.R.; Baker, D.C. [Pacific Northwest Lab., Richland, WA (United States)

1995-04-01T23:59:59.000Z

431

Dark energy induced by neutrino mixing  

E-Print Network [OSTI]

The energy content of the vacuum condensate induced by the neutrino mixing is interpreted as dynamically evolving dark energy.

Antonio Capolupo; Salvatore Capozziello; Giuseppe Vitiello

2006-12-11T23:59:59.000Z

432

Ly49Q, an ITIM-bearing NK receptor, positively regulates osteoclast differentiation  

SciTech Connect (OSTI)

Osteoclasts, multinucleated cells that resorb bone, play a key role in bone remodeling. Although immunoreceptor tyrosine-based activation motif (ITAM)-mediated signaling is critical for osteoclast differentiation, the significance of immunoreceptor tyrosine-based inhibitory motif (ITIM) has not been well understood. Here we report the function of Ly49Q, an Ly49 family member possessing an ITIM motif, in osteoclastogenesis. Ly49Q is selectively induced by receptor activator of nuclear factor-{kappa}B (NF-{kappa}B) ligand (RANKL) stimulation in bone marrow-derived monocyte/macrophage precursor cells (BMMs) among the Ly49 family of NK receptors. The knockdown of Ly49Q resulted in a significant reduction in the RANKL-induced formation of tartrate-resistance acid phosphatase (TRAP)-positive multinucleated cells, accompanied by a decreased expression of osteoclast-specific genes such as Nfatc1, Tm7sf4, Oscar, Ctsk, and Acp5. Osteoclastogenesis was also significantly impaired in Ly49Q-deficient cells in vitro. The inhibitory effect of Ly49Q-deficiency may be explained by the finding that Ly49Q competed for the association of Src-homology domain-2 phosphatase-1 (SHP-1) with paired immunoglobulin-like receptor-B (PIR-B), an ITIM-bearing receptor which negatively regulates osteoclast differentiation. Unexpectedly, Ly49Q deficiency did not lead to impaired osteoclast formation in vivo, suggesting the existence of a compensatory mechanism. This study provides an example in which an ITIM-bearing receptor functions as a positive regulator of osteoclast differentiation.

Hayashi, Mikihito [Department of Cell Signaling, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8549 (Japan) [Department of Cell Signaling, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8549 (Japan); Global Center of Excellence Program, International Research Center for Molecular Science in Tooth and Bone Diseases, Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8549 (Japan); Nakashima, Tomoki [Department of Cell Signaling, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8549 (Japan) [Department of Cell Signaling, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8549 (Japan); Japan Science and Technology Agency, ERATO, Takayanagi Osteonetwork Project, Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8549 (Japan); Global Center of Excellence Program, International Research Center for Molecular Science in Tooth and Bone Diseases, Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8549 (Japan); Kodama, Tatsuhiko [Research Center for Advanced Science and Technology, Department of Molecular Biology and Medicine, University of Tokyo, Tokyo 153-8904 (Japan)] [Research Center for Advanced Science and Technology, Department of Molecular Biology and Medicine, University of Tokyo, Tokyo 153-8904 (Japan); Makrigiannis, Andrew P. [Laboratory of Molecular Immunology, Institute de Recherches Cliniques de Montreal, Montreal, Quebec, Canada H2W 1R7 (Canada)] [Laboratory of Molecular Immunology, Institute de Recherches Cliniques de Montreal, Montreal, Quebec, Canada H2W 1R7 (Canada); Toyama-Sorimachi, Noriko [Department of Gastroenterology, Research Institute, International Medical Center of Japan, Toyama 1-21-1, Shinjuku-ku, Tokyo 162-8655 (Japan)] [Department of Gastroenterology, Research Institute, International Medical Center of Japan, Toyama 1-21-1, Shinjuku-ku, Tokyo 162-8655 (Japan); Takayanagi, Hiroshi, E-mail: taka.csi@tmd.ac.jp [Department of Cell Signaling, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8549 (Japan) [Department of Cell Signaling, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8549 (Japan); Japan Science and Technology Agency, ERATO, Takayanagi Osteonetwork Project, Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8549 (Japan); Global Center of Excellence Program, International Research Center for Molecular Science in Tooth and Bone Diseases, Yushima 1-5-45, Bunkyo-ku, Tokyo 113-8549 (Japan)

2010-03-12T23:59:59.000Z

433

Silencing MR-1 attenuates inflammatory damage in mice heart induced by AngII  

SciTech Connect (OSTI)

Myofibrillogenesis regulator-1(MR-1) can aggravate cardiac hypertrophy induced by angiotensin(Ang) II in mice through activation of NF-{kappa}B signaling pathway, and nuclear transcription factor (NF)-{kappa}B and activator protein-1(AP-1) regulate inflammatory and immune responses by increasing the expression of specific inflammatory genes in various tissues including heart. Whether inhibition of MR-1 expression will attenuate AngII-induced inflammatory injury in mice heart has not been explored. Herein, we monitored the activation of NF-{kappa}B and AP-1, together with expression of pro-inflammatory of interleukin(IL)-6, tumor necrosis factor(TNF)-{alpha}, vascular-cell adhesion molecule (VCAM)-1, platelet endothelial cell adhesion molecule (PECAM), and inflammatory cell infiltration in heart of mice which are induced firstly by AngII (PBS),then received MR-1-siRNA or control-siRNA injecting. We found that the activation of NF-{kappa}B and AP-1 was inhibited significantly, together with the decreased expression of IL-6, TNF-{alpha}, VCAM-1, and PECAM in AngII-induced mice myocardium in MR-1-siRNA injection groups compared with control-siRNA injecting groups. However, the expression level of MR-1 was not an apparent change in PBS-infused groups than in unoperation groups, and MR-1-siRNA do not affect the expression of MR-1 in PBS-infused mice. Our findings suggest that silencing MR-1 protected mice myocardium against inflammatory injury induced by AngII by suppression of pro-inflammatory transcription factors NF-{kappa}B and AP-1 signaling pathway.

Dai, Wenjian [Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Key Lab of Antibiotic Biotechnology, Ministry of Health, Beijing 100050 (China) [Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Key Lab of Antibiotic Biotechnology, Ministry of Health, Beijing 100050 (China); Hunan Environment-Biological Polytechnic College, Hengyang Hunan 421005 (China); Chen, Haiyang [Hunan Environment-Biological Polytechnic College, Hengyang Hunan 421005 (China)] [Hunan Environment-Biological Polytechnic College, Hengyang Hunan 421005 (China); Jiang, Jiandong [Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Key Lab of Antibiotic Biotechnology, Ministry of Health, Beijing 100050 (China)] [Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Key Lab of Antibiotic Biotechnology, Ministry of Health, Beijing 100050 (China); Kong, Weijia, E-mail: wjkong894@sohu.com [Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Key Lab of Antibiotic Biotechnology, Ministry of Health, Beijing 100050 (China)] [Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Key Lab of Antibiotic Biotechnology, Ministry of Health, Beijing 100050 (China); Wang, Yiguang, E-mail: wangyh456@yahoo.com.cn [Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Key Lab of Antibiotic Biotechnology, Ministry of Health, Beijing 100050 (China)] [Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Key Lab of Antibiotic Biotechnology, Ministry of Health, Beijing 100050 (China)

2010-01-15T23:59:59.000Z

434

Ursolic acid improves domoic acid-induced cognitive deficits in mice  

SciTech Connect (OSTI)

Our previous findings suggest that mitochondrial dysfunction is the mechanism underlying cognitive deficits induced by domoic acid (DA). Ursolic acid (UA), a natural triterpenoid compound, possesses many important biological functions. Evidence shows that UA can activate PI3K/Akt signaling and suppress Forkhead box protein O1 (FoxO1) activity. FoxO1 is an important regulator of mitochondrial function. Here we investigate whether FoxO1 is involved in the oxidative stress-induced mitochondrial dysfunction in DA-treated mice and whether UA inhibits DA-induced mitochondrial dysfunction and cognitive deficits through regulating the PI3K/Akt and FoxO1 signaling pathways. Our results showed that FoxO1 knockdown reversed the mitochondrial abnormalities and cognitive deficits induced by DA in mice through decreasing HO-1 expression. Mechanistically, FoxO1 activation was associated with oxidative stress-induced JNK activation and decrease of Akt phosphorylation. Moreover, UA attenuated the mitochondrial dysfunction and cognitive deficits through promoting Akt phosphorylation and FoxO1 nuclear exclusion in the hippocampus of DA-treated mice. LY294002, an inhibitor of PI3K/Akt signaling, significantly decreased Akt phosphorylation in the hippocampus of DA/UA mice, which weakened UA actions. These results suggest that UA could be recommended as a possible candidate for the prevention and therapy of cognitive deficits in excitotoxic brain disorders. - Highlights: • Ursolic acid (UA) is a naturally triterpenoid compound. • UA attenuated the mitochondrial dysfunction and cognitive deficits. • Mechanistically, UA activates PI3K/Akt signaling and suppresses FoxO1 activity. • UA could be recommended as a possible candidate for anti-excitotoxic brain disorders.

Wu, Dong-mei [School of Environment and Spatial Informatics, China University of Mining and Technology, Xuzhou 221008, Jiangsu Province (China); Key Laboratory for Biotechnology on Medicinal Plants of Jiangsu Province, School of Life Science, Xuzhou Normal University, Xuzhou 221116, Jiangsu Province (China); Lu, Jun, E-mail: lu-jun75@163.com [Key Laboratory for Biotechnology on Medicinal Plants of Jiangsu Province, School of Life Science, Xuzhou Normal University, Xuzhou 221116, Jiangsu Province (China); Zhang, Yan-qiu [School of Environment and Spatial Informatics, China University of Mining and Technology, Xuzhou 221008, Jiangsu Province (China); Zheng, Yuan-lin, E-mail: ylzheng@xznu.edu.cn [Key Laboratory for Biotechnology on Medicinal Plants of Jiangsu Province, School of Life Science, Xuzhou Normal University, Xuzhou 221116, Jiangsu Province (China); Hu, Bin [Key Laboratory for Biotechnology on Medicinal Plants of Jiangsu Province, School of Life Science, Xuzhou Normal University, Xuzhou 221116, Jiangsu Province (China); Cheng, Wei [School of Environment and Spatial Informatics, China University of Mining and Technology, Xuzhou 221008, Jiangsu Province (China); Zhang, Zi-feng; Li, Meng-qiu [Key Laboratory for Biotechnology on Medicinal Plants of Jiangsu Province, School of Life Science, Xuzhou Normal University, Xuzhou 221116, Jiangsu Province (China)

2013-09-01T23:59:59.000Z

435

Anti-inflammatory effect of resveratrol on TNF-{alpha}-induced MCP-1 expression in adipocytes  

SciTech Connect (OSTI)

Chronic low-grade inflammation characterized by adipose tissue macrophage accumulation and abnormal cytokine production is a key feature of obesity and type 2 diabetes. Adipose-tissue-derived monocyte chemoattractant protein (MCP)-1, induced by cytokines, has been shown to play an essential role in the early events during macrophage infiltration into adipose tissue. In this study we investigated the effects of resveratrol upon both tumor necrosis factor (TNF)-{alpha}-induced MCP-1 gene expression and its underlying signaling pathways in 3T3-L1 adipoctyes. Resveratrol was found to inhibit TNF-{alpha}-induced MCP-1 secretion and gene transcription, as well as promoter activity, which based on down-regulation of TNF-{alpha}-induced MCP-1 transcription. Nuclear factor (NF)-{kappa}B was determined to play a major role in the TNF-{alpha}-induced MCP-1 expression. Further analysis showed that resveratrol inhibited DNA binding activity of the NF-{kappa}B complex and subsequently suppressed NF-{kappa}B transcriptional activity in TNF-{alpha}-stimulated cells. Finally, the inhibition of MCP-1 may represent a novel mechanism of resveratrol in preventing obesity-related pathologies.

Zhu Jian [Department of Endocrinology, First Affiliated Hospital, Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029 (China); Key Laboratory of Human Functional Genomics of Jiangsu Province, School of Basic Medical Science, Jiangsu Province Diabetes Center, Nanjing Medical University, 140 Hanzhong Road, Nanjing 210029 (China); Yong Wei [Key Laboratory of Human Functional Genomics of Jiangsu Province, School of Basic Medical Science, Jiangsu Province Diabetes Center, Nanjing Medical University, 140 Hanzhong Road, Nanjing 210029 (China); Wu Xiaohong [Department of Endocrinology, First Affiliated Hospital, Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029 (China); Yu Ying; Lv Jinghuan [Key Laboratory of Human Functional Genomics of Jiangsu Province, School of Basic Medical Science, Jiangsu Province Diabetes Center, Nanjing Medical University, 140 Hanzhong Road, Nanjing 210029 (China); Liu Cuiping; Mao Xiaodong [Department of Endocrinology, First Affiliated Hospital, Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029 (China); Zhu Yunxia [Key Laboratory of Human Functional Genomics of Jiangsu Province, School of Basic Medical Science, Jiangsu Province Diabetes Center, Nanjing Medical University, 140 Hanzhong Road, Nanjing 210029 (China); Xu Kuanfeng [Department of Endocrinology, First Affiliated Hospital, Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029 (China); Han Xiao [Key Laboratory of Human Functional Genomics of Jiangsu Province, School of Basic Medical Science, Jiangsu Province Diabetes Center, Nanjing Medical University, 140 Hanzhong Road, Nanjing 210029 (China)], E-mail: hanxiao@njmu.edu.cn; Liu Chao [Department of Endocrinology, First Affiliated Hospital, Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029 (China)], E-mail: liuchao@nfmcn.com

2008-05-02T23:59:59.000Z

436

LM137/LM337 3-Terminal Adjustable Negative Regulators  

E-Print Network [OSTI]

LM137/LM337 3-Terminal Adjustable Negative Regulators General Description The LM137/LM337 design has been opti- mized for excellent regulation and low thermal transients. Further, the LM137 virtually blowout-proof against overloads. The LM137/LM337 serve a wide variety of applications in- cluding

Ravikumar, B.

437

LM2940/LM2940C 1A Low Dropout Regulator  

E-Print Network [OSTI]

LM2940/LM2940C 1A Low Dropout Regulator General Description The LM2940/LM2940C positive voltage the regulator is in the dropout mode (VIN - VOUT 3V). Designed also for vehicular applications, the LM2940/ LM circuits and the load. The LM2940/ LM2940C cannot be harmed by temporary mirror-image in- sertion. Familiar

Berns, Hans-Gerd

438

LM137/LM337 3-Terminal Adjustable Negative Regulators  

E-Print Network [OSTI]

LM137/LM337 3-Terminal Adjustable Negative Regulators General Description The LM137/LM337. The circuit design has been opti- mized for excellent regulation and low thermal transients. Further, the LM them virtually blowout-proof against overloads. The LM137/LM337 serve a wide variety of applications in

Berns, Hans-Gerd

439

Regulation of Stock Externalities with Correlated Abatement Costsw  

E-Print Network [OSTI]

Regulation of Stock Externalities with Correlated Abatement Costsw LARRY KARP1;Ã? and JIANGFENG externality. The regulator and firms have asymmetric information about serially correlated abatement costs about abatement costs. Weitzman (1974) showed that there is a simple criterion for ranking the policies

Karp, Larry S.

440

NOTICE OF PROPOSED REGULATION AMENDMENT Date: March 22, 2007  

E-Print Network [OSTI]

.: Florida Solar Energy Center Operations 6C7-8.001 SUMMARY OF REGULATION AMENDMENT: The amendments INITIATED PROPOSED REGULATION AMENDMENT: Philip Fairey, Deputy Director of Florida Solar Energy CenterC7-8.001 Florida Solar Energy Center Operations. (1) The Florida Solar Energy Center, (herein called

Wu, Shin-Tson

Note: This page contains sample records for the topic "venezuela regulation induced" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


441

NOTICE OF REGULATION REPEAL Date: July 1, 2010  

E-Print Network [OSTI]

, Florida Solar Energy Center COMMENTS CONCERNING THE REGULATION REPEAL SHOULD BE SUBMITTED WITHIN 14 DAYS REGULATION REPEAL: UCF-8.001 Florida Solar Energy Center Operations. (1) The Florida Solar Energy Center-5703. The development of #12;standards and testing criteria for solar energy systems, testing and evaluation

Wu, Shin-Tson

442

Updated June 16, 2003 Advanced Workshop in Regulation and Competition  

E-Print Network [OSTI]

Market Kevin Woodruff: Re-Restructuring the Electricity Industry: Identifying Roles for the Private: Emerging Issues in the Regulation of Utility: Power Procurement in Restructured Electricity Markets Robert Michaels: Market Monitoring in Electricity: What can We Learn from the Economics of Regulation? 6:00 - 9

Lin, Xiaodong

443

Centre for the study of Regulated Industries PUBLICATIONS &  

E-Print Network [OSTI]

, National Audit Office · Social issues in energy and water ~ Professor Cosmo Graham, University of Leicester Norton of Louth, University of Hull · The National Audit Office's audit programme ~ Ed Humpherson Nisbet & Alan Greig, QCA · Energy regulation ~ Maxine Frerk, Ofgem · Food standards regulation ~ Dame

Burton, Geoffrey R.

444

NOTICE OF PROPOSED REGULATION AMENDMENT Date: August 18, 2005  

E-Print Network [OSTI]

Plate Liquid Type Solar Collectors," Standard 96-1980 of the American Society of Heating, Refrigeration.: Solar Collector Testing Standards 6C7-8.002 SUMMARY OF REGULATION AMENDMENT: This regulation is revised to reflect updated information regarding the testing and standards for solar thermal collectors

Wu, Shin-Tson

445

actin dynamics regulate: Topics by E-print Network  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

actin dynamics regulate First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Regulation of Actin Dynamics in...

446

NOTICE OF PROPOSED REGULATION AMENDMENT Date: August 18, 2005  

E-Print Network [OSTI]

, Deputy Director of Florida Solar Energy Center COMMENTS CONCERNING THE PROPOSED REGULATION AMENDMENT in the solar hearing industry and to refer to updated standards prepared by the Florida Solar Energy Center TEXT OF THE PROPOSED REGULATION AMENDMENT: 6C7-8.005 SolarThermal and Photovoltaic Domestic Water

Wu, Shin-Tson

447

Automotive friction-induced noises A. Elmaiana  

E-Print Network [OSTI]

Automotive friction-induced noises A. Elmaiana , J.-M. Duffala , F. Gautiera , C. Pezeratb and J, France 3143 #12;Friction-induced noises are numerous in the automotive field. They also involve a large friction-induced noises with simple structures and automotive materials. Qualitative sensitivity studies

Paris-Sud XI, Université de

448

Irradiation-induced phenomena in carbon  

E-Print Network [OSTI]

Chapter 1 Irradiation-induced phenomena in carbon nanotubes To appear in "Chemistry of Carbon@acclab.helsinki.fi 1 #12;2CHAPTER 1. IRRADIATION-INDUCED PHENOMENA IN CARBON NANOTUBES #12;Contents 1 Irradiation-induced phenomena in carbon nanotubes 1 1.1 Introduction

Krasheninnikov, Arkady V.

449

Identification of GPR65, a novel regulator of matrix metalloproteinases using high through-put screening  

SciTech Connect (OSTI)

Highlights: •A novel mechanism of MMP3 regulation by proton-sensing G-protein-coupled receptors was defined. •GPR65 was identified to induce the MMP3 expression. •GPR65 mediated MMP induction under acidic conditions. •AP-1 binding site in MMP3 promoter was crucial for MMP3 induction. •GPR65 overexpression can accelerate the invision of A549 cells. -- Abstract: Matrix metalloproteinases (MMPs) are over-expressed in nearly all cancers. To study novel regulatory factors of MMP expression in head and neck cancer (HNC), we screened a total of 636 candidate genes encoding putative human transmembrane proteins using MMP promoter reporter in a dual luciferase assay system. Three genes GPR65, AXL and TNFRSF10B dramatically activated the induction of MMP3 expression. The induction of MMP expression by GPR65 was further confirmed in A549 and/or FaDu cells. GPR65 mediated MMP induction under acidic conditions. The AP-1 binding site in MMP3 promoter was crucial for MMP3 induction. Moreover, the A549 cells infected by recombinant adenovirus of GPR65 showed accelerated cell invasion. In conclusion, we validate that GPR65 is vital regulatory genes upstream of MMP3, and define a novel mechanism of MMP3 regulation by proton-sensing G-protein-coupled receptors.

Xu, Hongbo; Chen, Xiaohong; Huang, Junwei [Department of Otolaryngology-Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Key Laboratory of Otolaryngology Head and Neck Surgery, Beijing (China)] [Department of Otolaryngology-Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Key Laboratory of Otolaryngology Head and Neck Surgery, Beijing (China); Deng, Weiwei [Functional Genomics Group, Chinese National Human Genome Center (CHGB) at Beijing (China)] [Functional Genomics Group, Chinese National Human Genome Center (CHGB) at Beijing (China); Zhong, Qi [Department of Otolaryngology-Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Key Laboratory of Otolaryngology Head and Neck Surgery, Beijing (China)] [Department of Otolaryngology-Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Key Laboratory of Otolaryngology Head and Neck Surgery, Beijing (China); Yue, Changli [Department of Pathology, Beijing Tongren Hospital, Capital Medical University, Beijing (China)] [Department of Pathology, Beijing Tongren Hospital, Capital Medical University, Beijing (China); Wang, Pingzhang, E-mail: wangpzh@bjmu.edu.cn [Department of Immunology, School of Basic Medical Sciences, Peking University Health Science Center, Peking University Center for Human Disease Genomics, Key Laboratory of Medical Immunology, Ministry of Health (China) [Department of Immunology, School of Basic Medical Sciences, Peking University Health Science Center, Peking University Center for Human Disease Genomics, Key Laboratory of Medical Immunology, Ministry of Health (China); Functional Genomics Group, Chinese National Human Genome Center (CHGB) at Beijing (China); Huang, Zhigang, E-mail: enthuangzhigang@sohu.com [Department of Otolaryngology-Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Key Laboratory of Otolaryngology Head and Neck Surgery, Beijing (China)] [Department of Otolaryngology-Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Key Laboratory of Otolaryngology Head and Neck Surgery, Beijing (China)

2013-06-21T23:59:59.000Z

450

Extracellular Matrix-Regulated Gene Expression RequiresCooperation of SWI/SNF and Transcription Factors  

SciTech Connect (OSTI)

Extracellular cues play crucial roles in the transcriptional regulation of tissue-specific genes, but whether and how these signals lead to chromatin remodeling is not understood and subject to debate. Using chromatin immunoprecipitation (ChIP) assays and mammary-specific genes as models, we show here that extracellular matrix (ECM) molecules and prolactin cooperate to induce histone acetylation and binding of transcription factors and the SWI/SNF complex to the {beta}- and ?-casein promoters. Introduction of a dominant negative Brg1, an ATPase subunit of SWI/SNF complex, significantly reduced both {beta}- and ?-casein expression, suggesting that SWI/SNF-dependent chromatin remodeling is required for transcription of mammary-specific genes. ChIP analyses demonstrated that the ATPase activity of SWI/SNF is necessary for recruitment of RNA transcriptional machinery, but not for binding of transcription factors or for histone acetylation. Coimmunoprecipitation analyses showed that the SWI/SNF complex is associated with STAT5, C/EBP{beta}, and glucocorticoid receptor (GR). Thus, ECM- and prolactin-regulated transcription of the mammary-specific casein genes requires the concerted action of chromatin remodeling enzymes and transcription factors.

Xu, Ren; Spencer, Virginia A.; Bissell, Mina J.

2006-05-25T23:59:59.000Z

451

Regulation of ERK5 by insulin and angiotensin-II in vascular smooth muscle cells  

SciTech Connect (OSTI)

ERK5 is involved in proliferation of vascular smooth muscle cells (VSMC). The proliferative actions of insulin and angiotensin-II (A-II) in VSMC are mediated in part by ERK1/2. We hypothesized that insulin and A-II also regulate ERK5 activity in VSMC. Acute treatment (<60 min) with insulin or A-II increased phosphorylation of ERK1/2 at 15 min and ERK5 at 5 min. Chronic treatment ({<=}8 h) with insulin increased ERK1/2 phosphorylation by 4 h and ERK5 by 8 h. A-II-stimulated phosphorylation of ERK1/2 by 8 h and ERK5 by 4 h. The EC{sub 50} for insulin treatment effecting ERK1/2 and ERK5 phosphorylation was 1.5 and 0.1 nM, whereas the EC{sub 50} for A-II was 2 nM, each. Insulin plus A-II induced an additive effect only on ERK5 phosphorylation. Inhibition of insulin- and A-II-stimulated phosphorylation of ERK5 and ERK1/2 by PD98059 and Wortmannin exhibited differential and time-dependent effects. Taken together, these data indicate that insulin and A-II regulate the activity of ERK5, but different from that seen for ERK1/2.

Sharma, Girish [University of Colorado at Denver and Health Sciences Center, Aurora, CO (United States); Goalstone, Marc Lee [University of Colorado at Denver and Health Sciences Center, Aurora, CO (United States); Veterans Affairs Medical Center, Denver, CO 80220 (United States); E-mail: Marc.Goalstone@uchsc.edu

2007-03-23T23:59:59.000Z

452

Basic Fibroblast Growth Factor Regulates Persistent ERK Osciliations in Premaligant but not Malignant JB6 Cells  

SciTech Connect (OSTI)

basic fibroblast growth factor (bFGF or FGF2) plays an important role in epidermal wound healing in vivo and is associated with a persistent increased in the extracellular signal-regulated kinase (ERK) pathway in vitro. Here we have examined whether bFGF induces the closure of an experimental scratch wound in JB6 mouse epidermal cells and have explored the regulation of the ERK pathway by bFGF in the context of kinase oscillations. bFGF stimulation is associated with increases in cellular phospho-ERK and phospho-c-Jun levels. In addition, bFGF increases cell proliferation and a change in cell morphology (stellate appearance) in a dose-dependent fashion (0.1 – 100 ng/ml). bFGF treatment also promoted the closure of an experimental scratch wound in vitro. JB6 cells were stably transfected with an ERK1-GFP chimera to follow temporal ERK subcellular distribution patterns. We observe a persistent upregulation of the ERK pathway, as evidenced by a significant increase in nuclear ERK1-GFP levels at time points up to 24 hr after bFGF treatment. Interestingly, at the single cell level, ERK is observed to oscillate between nuclear and cytosolic compartments in response to bFGF treatment. Because this oscillatory behavior is asynchronous in the cell population, it is only clearly resolved at the single cell level. Collectively, data presented here are consistent with an important role for bFGF in wound healing and suggest a more complex regulation of the ERK pathway by bFGF than has previously been appreciated.

Weber, Thomas J.; Shankaran, Harish; Wiley, H. S.; Opresko, Lee K.; Chrisler, William B.; Quesenberry, Ryan D.

2010-05-02T23:59:59.000Z

453

2-(3-Methoxyphenyl)-5-methyl-1,8-naphthyridin-4(1H)-one (HKL-1) induces G2/M arrest and mitotic catastrophe in human leukemia HL-60 cells  

SciTech Connect (OSTI)

2-(3-Methoxyphenyl)-5-methyl-1,8-naphthyridin-4(1H)-one (HKL-1), a 2-phenyl-1,8-naphthyridin-4-one (2-PN) derivative, was synthesized and evaluated as an effective antimitotic agent in our laboratory. However, the molecular mechanisms are uncertain. In this study, HKL-1 was demonstrated to induce multipolar spindles, sustain mitotic arrest and generate multinucleated cells, all of which indicate mitotic catastrophe, in human leukemia HL-60 cells. Western blotting showed that HKL-1 induces mitotic catastrophe in HL-60 cells through regulating mitotic phase-specific kinases (down-regulating CDK1, cyclin B1, CENP-E, and aurora B) and regulating the expression of Bcl-2 family proteins (down-regulating Bcl-2 and up-regulating Bax and Bak), followed by caspase-9/-3 cleavage. These findings suggest that HKL-1 appears to exert its cytotoxicity toward HL-60 cells in culture by inducing mitotic catastrophe. Highlights: ? HKL-1 is a potential antimitotic agent against HL-60 cells. ? HKL-1 induces spindle disruption and sustained resulted in mitotic catastrophe. ? CENP-E and aurora B protein expressions significantly reduced. ? Bcl-2 family protein expressions altered and caspase-9/-3 activation. ? HKL-1 is an attractive candidate for possible use as a novel antimitotic agent.

Hsu, Mei-Hua; Liu, Chin-Yu; Lin, Chiao-Min; Chen, Yen-Jung; Chen, Chun-Jen; Lin, Yu-Fu; Huang, Li-Jiau [Graduate Institute of Pharmaceutical Chemistry, China Medical University, Taichung, Taiwan, ROC (China)] [Graduate Institute of Pharmaceutical Chemistry, China Medical University, Taichung, Taiwan, ROC (China); Lee, Kuo-Hsiung [Natural Products Research Laboratories, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599 (United States) [Natural Products Research Laboratories, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599 (United States); Chinese Medicine Research and Development Center, China Medical University and Hospital, Taichung, Taiwan, ROC (China); Kuo, Sheng-Chu, E-mail: sckuo@mail.cmu.edu.tw [Graduate Institute of Pharmaceutical Chemistry, China Medical University, Taichung, Taiwan, ROC (China)] [Graduate Institute of Pharmaceutical Chemistry, China Medical University, Taichung, Taiwan, ROC (China)

2012-03-01T23:59:59.000Z

454

Hypoxia reduces constitutive and TNF-{alpha}-induced expression of monocyte chemoattractant protein-1 in human proximal renal tubular cells  

SciTech Connect (OSTI)

Chronic hypoxia has been reported to be associated with macrophage infiltration in progressive forms of kidney disease. Here, we investigated the regulatory effects of hypoxia on constitutive and TNF-{alpha}-stimulated expression of monocyte chemoattractant protein-1 (MCP-1) in cultured human proximal renal tubular cells (HPTECs). Hypoxia reduced constitutive MCP-1 expression at the mRNA and protein levels in a time-dependent fashion for up to 48 h. Hypoxia also inhibited MCP-1 up-regulation by TNF-{alpha}. Treatment with actinomycin D showed that hypoxic down-regulation of MCP-1 expression resulted mainly from a decrease in the transcription but not the mRNA stability. Immunoblot and immunofluorescence analyses revealed that treatment with hypoxia or an iron chelator, desferrioxamine, induced nuclear accumulation of hypoxia-inducible factor-1{alpha} (HIF-1{alpha}) in HPTECs. Desferrioxamine mimicked hypoxia in the reduction of MCP-1 expression. However, overexpression of a dominant negative form of HIF-1{alpha} did not abolish the hypoxia-induced reduction of MCP-1 expression in HPTECs. These results suggest that hypoxia is an important negative regulator of monocyte chemotaxis to the renal inflamed interstitium, by reducing MCP-1 expression partly via hypoxia-activated signals other than the HIF-1 pathway.

Li Xuan [Division of Nephrology, Department of General Medicine, School of Medicine, Faculty of Medical Sciences, University of Fukui, Fukui (Japan); Kimura, Hideki [Division of Nephrology, Department of General Medicine, School of Medicine, Faculty of Medical Sciences, University of Fukui, Fukui (Japan)]. E-mail: hkimura@fmsrsa.fukui-med.ac.jp; Hirota, Kiichi [Department of Anesthesia, Tazuke Kofukai Medical Research Institute Kitano Hospital, Osaka (Japan); Department of Anesthesia, School of Medicine, Kyoto University, Kyoto (Japan); Sugimoto, Hidehiro [Division of Nephrology, Department of General Medicine, School of Medicine, Faculty of Medical Sciences, University of Fukui, Fukui (Japan); Yoshida, Haruyoshi [Division of Nephrology, Department of General Medicine, School of Medicine, Faculty of Medical Sciences, University of Fukui, Fukui (Japan)

2005-10-07T23:59:59.000Z

455

Cadmium induces autophagy through ROS-dependent activation of the LKB1-AMPK signaling in skin epidermal cells  

SciTech Connect (OSTI)

Cadmium is a toxic heavy metal which is environmentally and occupationally relevant. The mechanisms underlying cadmium-induced autophagy are not yet completely understood. The present study shows that cadmium induces autophagy, as demonstrated by the increase of LC3-II formation and the GFP-LC3 puncta cells. The induction of autophagosomes was directly visualized by electron microscopy in cadmium-exposed skin epidermal cells. Blockage of LKB1 or AMPK by siRNA transfection suppressed cadmium-induced autophagy. Cadmium-induced autophagy was inhibited in dominant-negative AMPK-transfected cells, whereas it was accelerated in cells transfected with the constitutively active form of AMPK. mTOR signaling, a negative regulator of autophagy, was downregulated in cadmium-exposed cells. In addition, cadmium generated reactive oxygen species (ROS) at relatively low levels, and caused poly(ADP-ribose) polymerase-1 (PARP) activation and ATP depletion. Inhibition of PARP by pharmacological inhibitors or its siRNA transfection suppressed ATP reduction and autophagy in cadmium-exposed cells. Furthermore, cadmium-induced autophagy signaling was attenuated by either exogenous addition of catalase and superoxide dismutase, or by overexpression of these enzymes. Consequently, these results suggest that cadmium-mediated ROS generation causes PARP activation and energy depletion, and eventually induces autophagy through the activation of LKB1-AMPK signaling and the down-regulation of mTOR in skin epidermal cells. - Highlights: > Cadmium, a toxic heavy metal, induces autophagic cell death through ROS-dependent activation of the LKB1-AMPK signaling. > Cadmium generates intracellular ROS at low levels and this leads to severe DNA damage and PARP activation, resulting in ATP depletion, which are the upstream events of LKB1-AMPK-mediated autophagy. > This novel finding may contribute to further understanding of cadmium-mediated diseases.

Son, Young-Ok; Wang Xin; Hitron, John Andrew [Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, KY 40536-0305 (United States); Zhang Zhuo [Department of Preventive Medicine and Environmental Health, College of Public Health, University of Kentucky, Lexington, KY 40536-0305 (United States); Cheng Senping; Budhraja, Amit; Ding Songze [Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, KY 40536-0305 (United States); Lee, Jeong-Chae [Institute of Oral Biosciences and BK21 Program, Research Center of Bioactive Materials, Chonbuk National University, Jeonju 561-756 (Korea, Republic of); Shi Xianglin, E-mail: xshi5@email.uky.edu [Graduate Center for Toxicology, College of Medicine, University of Kentucky, Lexington, KY 40536-0305 (United States)

2011-09-15T23:59:59.000Z

456

Field-regulated force by grafted polyelectrolytes  

E-Print Network [OSTI]

Generation of mechanical force regulated by external electric field is studied both theoretically and by molecular dynamics (MD) simulations. The force arises in deformable bodies linked to the free end of a grafted polyelectrolyte chain which is exposed to electric field that favours its adsorption. We consider a few target bodies with different force-deformation relations including (i) linear and (ii) cubic dependences as well as (iii) Hertzian-like force. Such force-deformation relations mimic the behaviour of (i) coiled and (ii) stretched polymer chains, respectively, or (iii) that of a squeezed colloidal particle. The magnitude of the arising force varies over a wide interval although the electric field alters within a relatively narrow range only. The predictions of our theory agree quantitatively well with the results of numerical simulations. Both cases of zero and finite electrical current are investigated and we do not obtain substantial differences in the force generated. The phenomenon studied could possibly be utilised to design, e.g., vice-like devices to fix nano-sized objects.

Christian Seidel; Yury A. Budkov; Nikolay V. Brilliantov

2014-11-08T23:59:59.000Z

457

How simple regulations can deeply reduce inequality  

E-Print Network [OSTI]

Many models of market dynamics make use of the idea of wealth exchanges among economic agents. A simple analogy compares the wealth in a society with the energy in a physical system, and the trade between agents to the energy exchange between molecules during collisions. However, while in physical systems the equipartition of energy is valid, in most exchange models for economic markets the system converges to a very unequal "condensed" state, where one or a few agents concentrate all the wealth of the society and the wide majority of agents shares zero or a very tiny fraction of the wealth. Here we present an exchange model where the goal is not only to avoid condensation but also to reduce the inequality; to carry out this objective the choice of interacting agents is not at random, but follows an extremal dynamics regulated by the wealth of the agent. The wealth of the agent with the minimum capital is changed at random and the difference between the ancient and the new wealth of this poorest agent is take...

Iglesias, J R

2010-01-01T23:59:59.000Z

458

Improving Collision Induced Dissociation (CID), High Energy Collision...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Collision Induced Dissociation (CID), High Energy Collision Dissociation (HCD), and Electron Transfer Dissociation Improving Collision Induced Dissociation (CID), High Energy...

459

Transition from Irradiation-Induced Amorphization to Crystallization...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

from Irradiation-Induced Amorphization to Crystallization in Nanocrystalline Silicon Carbide. Transition from Irradiation-Induced Amorphization to Crystallization in...

460

The Mineralogic Transformation of Ferrihydrite Induced by Heterogeneou...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

Transformation of Ferrihydrite Induced by Heterogeneous Reaction with Bioreduced Anthraquinone Disulfonate (AQDS The Mineralogic Transformation of Ferrihydrite Induced by...

Note: This page contains sample records for the topic "venezuela regulation induced" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


461

Prolyl oligopeptidase inhibition-induced growth arrest of human gastric cancer cells  

SciTech Connect (OSTI)

Highlights: •We examined the effects of prolyl oligopeptidase (POP) inhibition on p53 null gastric cancer cell growth. •POP inhibition-induced cell growth suppression was associated with an increase in a quiescent G{sub 0} state. •POP might regulate the exit from and/or reentry into the cell cycle. -- Abstract: Prolyl oligopeptidase (POP) is a serine endopeptidase that hydrolyzes post-proline peptide bonds in peptides that are <30 amino acids in length. We recently reported that POP inhibition suppressed the growth of human neuroblastoma cells. The growth suppression was associated with pronounced G{sub 0}/G{sub 1} cell cycle arrest and increased levels of the CDK inhibitor p27{sup kip1} and the tumor suppressor p53. In this study, we investigated the mechanism of POP inhibition-induced cell growth arrest using a human gastric cancer cell line, KATO III cells, which had a p53 gene deletion. POP specific inhibitors, 3-((4-[2-(E)-styrylphenoxy]butanoyl)-L-4-hydroxyprolyl)-thiazolidine (SUAM-14746) and benzyloxycarbonyl-thioprolyl-thioprolinal, or RNAi-mediated POP knockdown inhibited the growth of KATO III cells irrespective of their p53 status. SUAM-14746-induced growth inhibition was associated with G{sub 0}/G{sub 1} cell cycle phase arrest and increased levels of p27{sup kip1} in the nuclei and the pRb2/p130 protein expression. Moreover, SUAM-14746-mediated cell cycle arrest of KATO III cells was associated with an increase in the quiescent G{sub 0} state, defined by low level staining for the proliferation marker, Ki-67. These results indicate that POP may be a positive regulator of cell cycle progression by regulating the exit from and/or reentry into the cell cycle by KATO III cells.

Suzuki, Kanayo [Laboratory of Cell Biology, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094 (Japan)] [Laboratory of Cell Biology, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094 (Japan); Sakaguchi, Minoru, E-mail: sakaguti@gly.oups.ac.jp [Laboratory of Cell Biology, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094 (Japan)] [Laboratory of Cell Biology, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094 (Japan); Tanaka, Satoshi [Laboratory of Cell Biology, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094 (Japan)] [Laboratory of Cell Biology, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094 (Japan); Yoshimoto, Tadashi [Department of Life Science, Setsunan University, 17-8 Ikeda-Nakamachi, Neyagawa, Osaka 572-8508 (Japan)] [Department of Life Science, Setsunan University, 17-8 Ikeda-Nakamachi, Neyagawa, Osaka 572-8508 (Japan); Takaoka, Masanori [Laboratory of Cell Biology, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094 (Japan)] [Laboratory of Cell Biology, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094 (Japan)

2014-01-03T23:59:59.000Z

462

NF-kB activity-dependent P-selectin involved in ox-LDL-induced foam cell formation in U937 cell  

SciTech Connect (OSTI)

Highlights: {yields} Ox-LDL induced foam cell formation in the human U937 promonocytic cell line in a dose- and time-dependent manner. {yields} Ox-LDL induced expression of P-selectin through degradation of IkBa and augment of NF-kB activity and protein level during macrophage-derived foam cell formation. {yields} P-selectin and NF-kB may be identified as pivotal regulators of ox-LDL-induced foam cell formation. {yields} Therapy based on the inhibition of P-selectin and NF-kB may complement conventional treatments to prevent atherosclerosis. -- Abstract: Oxidized low-density lipoprotein (ox-LDL) plays a critical role in regulation of atherosclerosis. However, little is known about the role of Nuclear factor kB (NF-kB) activity-dependent P-selectin in ox-LDL-induced foam cell formation during atherosclerosis. In this study, we first investigated ox-LDL induced foam cell formation in the human U937 promonocytic cell line in a dose- and time-dependent manner. Treatment of U937 cells with ox-LDL increased lipid accumulation as well as intracellular cholesterol content. Next, a comparative analysis of gene expression profiling using cDNA microarray and Real-time-PCR indicated that ox-LDL exposure induced, in three treated groups, an extremely marked increase in the mRNA level of P-selectin. Protein levels of P-selectin and its upstream regulators IkBa and NF-kB showed that NF-kB pathway is involved in the ox-LDL-induced foam cell formation. Finally, overexpression of NF-kB significantly accelerated, whereas, inhibition of NF-kB with siRNA remarkably attenuated ox-LDL-induced macrophage-derived foam cell formation. It was concluded that the activity of NF-kB is augmented during macrophage-derived foam cell formation. Activation of NF-kB increased, whereas, inhibition of NF-kB decreased ox-LDL-induced P-selectin expression and lipid accumulation in macrophages, suggesting ox-LDL induced expression of P-selectin through degradation of IkBa and activation of NF-kB in the regulation of foam cell formation.

Wang, Yi, E-mail: wangyi2004a@126.com [Department of Cardiology, Shanghai First People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200080 (China)] [Department of Cardiology, Shanghai First People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200080 (China); Wang, Xiang; Sun, Minghui; Zhang, Zhenyu; Cao, Heng; Chen, Xiaoqing [Department of Cardiology, Shanghai First People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200080 (China)] [Department of Cardiology, Shanghai First People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200080 (China)

2011-08-05T23:59:59.000Z

463

A primer on incentive regulation for electric utilities  

SciTech Connect (OSTI)

In contemplating a regulatory approach, the challenge for regulators is to develop a model that provides incentives for utilities to engage in socially desirable behavior. In this primer, we provide guidance on this process by discussing (1) various models of economic regulation, (2) problems implementing these models, and (3) the types of incentives that various models of regulation provide electric utilities. We address five regulatory models in depth. They include cost-of-service regulation in which prudently incurred costs are reflected dollar-for-dollar in rates and four performance-based models: (1) price-cap regulation, in which ceilings are placed on the average price that a utility can charge its customers; (2) revenue-cap regulation, in which a ceiling is placed on revenues; (3) rate-of-return bandwidth regulation, in which a utility`s rates are adjusted if earnings fall outside a {open_quotes}band{close_quotes} around equity returns; and (4) targeted incentives, in which a utility is given incentives to improve specific components of its operations. The primary difference between cost-of-service and performance-based approaches is the latter sever the tie between costs and prices. A sixth, {open_quotes}mixed approach{close_quotes} combines two or more of the five basic ones. In the recent past, a common mixed approach has been to combine targeted incentives with cost-of-service regulation. A common example is utilities that are subject to cost-of-service regulation are given added incentives to increase the efficiency of troubled electric-generating units.

Hill, L.J.

1995-10-01T23:59:59.000Z

464

Advanced Workshop in Regulation and Competition COMPETITIVE CHANGE IN NETWORK INDUSTRIES  

E-Print Network [OSTI]

in Pricing and Technology %Restructuring &Strategies under Competition and Deregulation %Incentive Regulation & James Cater: Restructuring in a Low-Cost State: The Virginia Experience INCENTIVE REGULATION Chair Incentive Regulation "Cause" Degradation of Retail Telephone Service Quality? Ingo Vogelsang: Incentive

Lin, Xiaodong

465

The end of core : should disruptive innovation in telecommunication invoke discontinuous regulation?  

E-Print Network [OSTI]

This research analyzes how a telecommunications regulator can balance regulation with innovation, at a reasonable cost. This question has gained critical importance for telecom regulators as the unregulated Internet ...

Vaishnav, Chintan

2010-01-01T23:59:59.000Z

466

Research on Fuzzy Regulation Strategies in the Constant Air Volume Air Conditioning System  

E-Print Network [OSTI]

The energy consumption of the constant air volume (CAV) system largely depends on the regulation strategies. Although some air conditioning systems are equipped with automatic regulation devices, others lack effective regulation strategies. To avoid...

Bai, T.; Zhang, J.; Ning, N.; Tong, K.; Wu, Y.; Wang, H.

2006-01-01T23:59:59.000Z

467

Colorado 4 CCR 723-3001, Definitions for Rules Regulating Electric...  

Open Energy Info (EERE)

CCR 723-3001, Definitions for Rules Regulating Electric Utilities Jump to: navigation, search OpenEI Reference LibraryAdd to library Legal Document- RegulationRegulation: Colorado...

468

41st Annual Securities Regulation Institute January 27-29, 2014 Coronado, California 41st Annual  

E-Print Network [OSTI]

from the general counsel's per- spective-day event, attendees learn from regulators who write the new regulations, judges who interpret the law regulations, judges who interpret the law to resolve complex disputes, and prominent practitioners who guide

Shahriar, Selim

469

2 C.C.R. 410 - Rules and Regulations for the Management and Control...  

Open Energy Info (EERE)

and Regulations for the Management and Control of Designated Ground Water Jump to: navigation, search OpenEI Reference LibraryAdd to library Legal Document- RegulationRegulation: 2...

470

Industry Self-Regulation as a Means to Promote Nonproliferation  

SciTech Connect (OSTI)

Companies within numerous industries that have been “early adopters” of self-regulation concept, considering the environment and society alongside business issues, have realized several benefits and some competitive advantage while substantially improving their environmental performance. Given that proliferation prevention is also a public good, our premise is that the experience gained and lessons learned from the self-regulation initiative in other industries and more broadly in the arena of sustainable development provide a basis for examining the feasibility of developing self-regulation mechanisms applicable to industries involved with sensitive technologies (nuclear, radiological source, and other dual-use industries)

Hund, Gretchen; Elkhamri, Oksana O.

2005-10-01T23:59:59.000Z

471

Opposing regulation of cytochrome P450 expression by CAR and PXR in hypothyroid mice  

SciTech Connect (OSTI)

Clinical hypothyroidism affects various metabolic processes including drug metabolism. CYP2B and CYP3A are important cytochrome P450 drug metabolizing enzymes that are regulated by the xenobiotic receptors constitutive androstane receptor (CAR, NR1I3) and pregnane X receptor (PXR, NR1I2). We evaluated the regulation of the hepatic expression of CYPs by CAR and PXR in the hypothyroid state induced by a low-iodine diet containing 0.15% propylthiouracil. Expression of Cyp3a11 was suppressed in hypothyroid C57BL/6 wild type (WT) mice and a further decrement was observed in hypothyroid CAR{sup ?/?} mice, but not in hypothyroid PXR{sup ?/?} mice. In contrast, expression of Cyp2b10 was induced in both WT and PXR{sup ?/?} hypothyroid mice, and this induction was abolished in CAR{sup ?/?} mice and in and CAR{sup ?/?} PXR{sup ?/?} double knockouts. CAR mRNA expression was increased by hypothyroidism, while PXR expression remained unchanged. Carbamazepine (CBZ) is a commonly used antiepileptic that is metabolized by CYP3A isoforms. After CBZ treatment of normal chow fed mice, serum CBZ levels were highest in CAR{sup ?/?} mice and lowest in WT and PXR{sup ?/?} mice. Hypothyroid WT or PXR{sup ?/?} mice survived chronic CBZ treatment, but all hypothyroid CAR{sup ?/?} and CAR{sup ?/?} PXR{sup ?/?} mice died, with CAR{sup ?/?}PXR{sup ?/?} mice surviving longer than CAR{sup ?/?} mice (12.3 ± 3.3 days vs. 6.3 ± 2.1 days, p = 0.04). All these findings suggest that hypothyroid status affects xenobiotic metabolism, with opposing responses of CAR and PXR and their CYP targets that can cancel each other out, decreasing serious metabolic derangement in response to a xenobiotic challenge. -- Highlights: ? Hypothyroid status activates CAR in mice and induces Cyp2b10 expression. ? Hypothyroid status suppresses PXR activity in mice and represses Cyp3a11 expression. ? These responses balance each other out in normal mice. ? Hypothyroidism sensitizes CAR null mice to toxic effects of carbamazepine.

Park, Young Joo [Department of Internal Medicine, Seoul National University College of Medicine (Korea, Republic of) [Department of Internal Medicine, Seoul National University College of Medicine (Korea, Republic of); Seoul National University Bundang Hospital, Seoul (Korea, Republic of); Lee, Eun Kyung [Department of Internal Medicine, Seoul National University College of Medicine (Korea, Republic of)] [Department of Internal Medicine, Seoul National University College of Medicine (Korea, Republic of); Lee, Yoon Kwang [Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030 (United States)] [Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030 (United States); Park, Do Joon; Jang, Hak Chul [Department of Internal Medicine, Seoul National University College of Medicine (Korea, Republic of)] [Department of Internal Medicine, Seoul National University College of Medicine (Korea, Republic of); Moore, David D., E-mail: moore@bcm.edu [Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030 (United States)

2012-09-01T23:59:59.000Z

472

Single particle-induced latchup  

SciTech Connect (OSTI)

This paper presents an up-to-date overview of the single-event latchup (SEL) hard failure mode encountered in electronic device applications involving heavy ion environment. This phenomenon is specific to CMOS technology. Single-event latchup is discussed after a short description of the effects induced by the interaction of a heavy ion with silicon. Understanding these effects is necessary to understand the different failures. This paper includes a description of the latchup phenomenon and the different triggering modes, reviews of models and hardening solutions, and finally presents new developments in simulation approaches.

Bruguier, G.; Palau, J.M. [Univ. Montpellier II (France). Centre d`Electronique de Montpellier] [Univ. Montpellier II (France). Centre d`Electronique de Montpellier

1996-04-01T23:59:59.000Z

473

Cell recognition molecule L1 promotes embryonic stem cell differentiation through the regulation of cell surface glycosylation  

SciTech Connect (OSTI)

Highlights: •Down-regulating FUT9 and ST3Gal4 expression blocks L1-induced neuronal differentiation of ESCs. •Up-regulating FUT9 and ST3Gal4 expression in L1-ESCs depends on the activation of PLC?. •L1 promotes ESCs to differentiate into neuron through regulating cell surface glycosylation. -- Abstract: Cell recognition molecule L1 (CD171) plays an important role in neuronal survival, migration, differentiation, neurite outgrowth, myelination, synaptic plasticity and regeneration after injury. Our previous study has demonstrated that overexpressing L1 enhances cell survival and proliferation of mouse embryonic stem cells (ESCs) through promoting the expression of FUT9 and ST3Gal4, which upregulates cell surface sialylation and fucosylation. In the present study, we examined whether sialylation and fucosylation are involved in ESC differentiation through L1 signaling. RNA interference analysis showed that L1 enhanced differentiation of ESCs into neurons through the upregulation of FUT9 and ST3Gal4. Furthermore, blocking the phospholipase C? (PLC?) signaling pathway with either a specific PLC? inhibitor or knockdown PLC? reduced the expression levels of both FUT9 and ST3Gal4 mRNAs and inhibited L1-mediated neuronal differentiation. These results demonstrate that L1 promotes neuronal differentiation from ESCs through the L1-mediated enhancement of FUT9 and ST3Gal4 expression.

Li, Ying [Department of Biochemistry and Molecular Biology, Dalian Medical University, Dalian 116044 (China) [Department of Biochemistry and Molecular Biology, Dalian Medical University, Dalian 116044 (China); Department of Clinical Laboratory, Second Affiliated Hospital of Dalian Medical University, Dalian 116023 (China); Huang, Xiaohua [Department of Biochemistry and Molecular Biology, Dalian Medical University, Dalian 116044 (China) [Department of Biochemistry and Molecular Biology, Dalian Medical University, Dalian 116044 (China); Department of Clinical Biochemistry, College of Laboratory Medicine, Dalian Medical University, Dalian 116044 (China); An, Yue [Department of Clinical Laboratory, Second Affiliated Hospital of Dalian Medical University, Dalian 116023 (China)] [Department of Clinical Laboratory, Second Affiliated Hospital of Dalian Medical University, Dalian 116023 (China); Ren, Feng [Department of Biochemistry and Molecular Biology, Dalian Medical University, Dalian 116044 (China)] [Department of Biochemistry and Molecular Biology, Dalian Medical University, Dalian 116044 (China); Yang, Zara Zhuyun; Zhu, Hongmei; Zhou, Lei [The Key Laboratory of Stem Cell and Regenerative Medicine, Institute of Molecular and Clinical Medicine, Kunming Medical University, Kunming 650228 (China) [The Key Laboratory of Stem Cell and Regenerative Medicine, Institute of Molecular and Clinical Medicine, Kunming Medical University, Kunming 650228 (China); Department of Anatomy and Developmental Biology, Monash University, Clayton 3800 (Australia); He, Xiaowen; Schachner, Melitta [Keck Center for Collaborative Neuroscience and Department of Cell Biology and Neuroscience, Rutgers University, New Brunswick, NJ (United States)] [Keck Center for Collaborative Neuroscience and Department of Cell Biology and Neuroscience, Rutgers University, New Brunswick, NJ (United States); Xiao, Zhicheng, E-mail: zhicheng.xiao@monash.edu [The Key Laboratory of Stem Cell and Regenerative Medicine, Institute of Molecular and Clinical Medicine, Kunming Medical University, Kunming 650228 (China) [The Key Laboratory of Stem Cell and Regenerative Medicine, Institute of Molecular and Clinical Medicine, Kunming Medical University, Kunming 650228 (China); Department of Anatomy and Developmental Biology, Monash University, Clayton 3800 (Australia); Ma, Keli, E-mail: makeli666@aliyun.com [Department of Biochemistry and Molecular Biology, Dalian Medical University, Dalian 116044 (China)] [Department of Biochemistry and Molecular Biology, Dalian Medical University, Dalian 116044 (China); Li, Yali, E-mail: yalilipaper@gmail.com [Department of Biochemistry and Molecular Biology, Dalian Medical University, Dalian 116044 (China) [Department of Biochemistry and Molecular Biology, Dalian Medical University, Dalian 116044 (China); Department of Anatomy, National University of Singapore, Singapore 119078 (Singapore)

2013-10-25T23:59:59.000Z

474

Axion-induced oscillations of cooperative electric field in a cosmic magneto-active plasma  

E-Print Network [OSTI]

We consider one cosmological application of an axionic extension of the Maxwell-Vlasov theory, which describes axionically induced oscillatory regime in the state of global magnetic field evolving in the anisotropic expanding (early) universe. We show that the cooperative electric field in the relativistic plasma, being coupled to the pseudoscalar (axion) and global magnetic fields, plays the role of a regulator in this three-level system; in particular, the cooperative (Vlasov) electric field converts the regime of anomalous growth of the pseudoscalar field, caused by the axion-photon coupling at the inflationary epoch of the universe expansion, into an oscillatory regime with finite density of relic axions. We analyze solutions to the dispersion equations for the axionically induced cooperative oscillations of the electric field in the relativistic plasma.

Balakin, Alexander B; Zayats, Alexei E

2014-01-01T23:59:59.000Z

475

Axion-induced oscillations of cooperative electric field in a cosmic magneto-active plasma  

E-Print Network [OSTI]

We consider one cosmological application of an axionic extension of the Maxwell-Vlasov theory, which describes axionically induced oscillatory regime in the state of global magnetic field evolving in the anisotropic expanding (early) universe. We show that the cooperative electric field in the relativistic plasma, being coupled to the pseudoscalar (axion) and global magnetic fields, plays the role of a regulator in this three-level system; in particular, the cooperative (Vlasov) electric field converts the regime of anomalous growth of the pseudoscalar field, caused by the axion-photon coupling at the inflationary epoch of the universe expansion, into an oscillatory regime with finite density of relic axions. We analyze solutions to the dispersion equations for the axionically induced cooperative oscillations of the electric field in the relativistic plasma.

Alexander B. Balakin; Ruslan K. Muharlyamov; Alexei E. Zayats

2014-05-26T23:59:59.000Z

476

Page 1 of 5 Narrative Description of Hydraulic Fracturing Draft Regulations  

E-Print Network [OSTI]

Page 1 of 5 Narrative Description of Hydraulic Fracturing Draft Regulations The Department of Conservation has released a discussion draft of hydraulic fracturing (HF) regulations. This narrative attempts

477

Rules and Regulations for the Investigation and Remediation of Hazardous Material Releases (Rhode Island)  

Broader source: Energy.gov [DOE]

These regulations establish procedures for the investigation and remediation of contamination resulting from the unpermitted release of hazardous materials. The regulations aim to protect water...

478

Chromatin landscaping in algae reveals novel regulation pathway for biofuels production  

E-Print Network [OSTI]

regulation pathway for biofuels production Chew Yee Ngan ,regulation pathway for biofuels production Chew Yee Ngan,for the development of biofuels. Biofuels are produced from

Ngan, Chew Yee

2014-01-01T23:59:59.000Z

479

Transcriptional Regulation in Algae, Fungi and Plants: Mating Loci, Splicing, and miRNAs  

E-Print Network [OSTI]

from organisms ranging from algae to fungi and plants. WeTranscriptional Regulation in Algae, Fungi and Plants:Transcriptional Regulation in Algae, Fungi and Plants:

Douglass, Stephen Michael

2014-01-01T23:59:59.000Z

480

E-Print Network 3.0 - adam-17 regulates endothelial Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

aorta of the normal rabbit exhibits focal sites Summary: to repair this injury. Because fluid mechanical forces regulate such fundamental endothelial processes... regulates the...

Note: This page contains sample records for the topic "venezuela regulation induced" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


481

E-Print Network 3.0 - acids differentially regulate Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

acids might participate in MP2C regulation... involved in MAP kinase regulation in alfalfa, is inhibited by fatty ... Source: Hirt, Heribert - Department of Genetics,...

482

E-Print Network 3.0 - acquisition regulation supplement Sample...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

NOTICE OF PROPOSED REGULATION AMENDMENT Date: July 29, 2009 Summary: 's acquisition (by lease or purchase), management or sale of real property. 12;(2) These regulations shall...

483

Arabidopsis Adapts to Copper Deficient Conditions via SPL7, a Master Regulator for Copper Homeostasis  

E-Print Network [OSTI]

systemic down-regulation of copper protein expression inresponse to low copper availability in Arabidopsis. J. Biol.A regulator of nutritional copper signaling in Chlamydomonas

Yamasaki, Hiroaki; Shikanai, Toshiharu

2009-01-01T23:59:59.000Z

484

Rules and Regulations for Dredging and the Management of Dredged Material (Rhode Island)  

Broader source: Energy.gov [DOE]

These regulations apply to dredging conducted in a marine environment. The regulations aim to ensure that dredging does not unduly impact groundwater and surface water quality while streamlining...

485

Solid Waste Regulation No. 8- Solid Waste Composting Facilities (Rhode Island)  

Broader source: Energy.gov [DOE]

Facilities which compost putrescible waste and/or leaf and yard waste are subject to these regulations. The regulations establish permitting, registration, and operational requirements for...

486

Rules and Regulations for Underground Storage Facilities Used for Petroleum Products and Hazardous Materials (Rhode Island)  

Broader source: Energy.gov [DOE]

These regulations apply to underground storage facilities for petroleum and hazardous waste, and seek to protect water resources from contamination. The regulations establish procedures for the...

487

Division of Water, Part 675: Great Lakes Water Withdrawal Registration Regulations (New York)  

Broader source: Energy.gov [DOE]

These regulations set forth requirements for the registration of water withdrawals and reporting of water losses from the Great Lakes Basin. The regulations apply to water withdrawals from...

488

National Energy Board Act Part VI (Oil and Gas) Regulations (Canada)  

Broader source: Energy.gov [DOE]

These regulations from the National Energy Board cover licensing for oil and gas, including the exportation and importation of natural gas. The regulations also cover inspections, reporting...

489

E-Print Network 3.0 - activation linker regulates Sample Search...  

Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

regulated isozymes. The XY linker... that the XY linker serves to autoinhibit PLC-b2 and that regulated removal of the linker from the active... . Similar ... Source:...

490

Ion-induced nuclear radiotherapy  

DOE Patents [OSTI]

Ion-induced Nuclear Radiotherapy (INRT) is a technique for conducting radiosurgery and radiotherapy with a very high degree of control over the spatial extent of the irradiated volume and the delivered dose. Based upon the concept that low energy, ion induced atomic and nuclear reactions can be used to produce highly energetic reaction products at the site of a tumor, the INRT technique is implemented through the use of a conduit-needle or tube which conducts a low energy ion beam to a position above or within the intended treatment area. At the end of the conduit-needle or tube is a specially fabricated target which, only when struck by the ion beam, acts as a source of energetic radiation products. The inherent limitations in the energy, and therefore range, of the resulting reaction products limits the spatial extent of irradiation to a pre-defined volume about the point of reaction. Furthermore, since no damage is done to tissue outside this irradiated volume, the delivered dose may be made arbitrarily large. INRT may be used both as a point-source of radiation at the site of a small tumor, or as a topical bath of radiation to broad areas of diseased tissue.

Horn, Kevin M. (Albuquerque, NM); Doyle, Barney L. (Albuquerque, NM)

1996-01-01T23:59:59.000Z

491

Ion-induced nuclear radiotherapy  

DOE Patents [OSTI]

Ion-induced Nuclear Radiotherapy (INRT) is a technique for conducting radiosurgery and radiotherapy with a very high degree of control over the spatial extent of the irradiated volume and the delivered dose. Based upon the concept that low energy, ion induced atomic and nuclear reactions can be used to produce highly energetic reaction products at the site of a tumor, the INRT technique is implemented through the use of a conduit-needle or tube which conducts a low energy ion beam to a position above or within the intended treatment area. At the end of the conduit-needle or tube is a specially fabricated target which, only when struck by the ion beam, acts as a source of energetic radiation products. The inherent limitations in the energy, and therefore range, of the resulting reaction products limits the spatial extent of irradiation to a pre-defined volume about the point of reaction. Furthermore, since no damage is done to tissue outside this irradiated volume, the delivered dose may be made arbitrarily large. INRT may be used both as a point-source of radiation at the site of a small tumor, or as a topical bath of radiation to broad areas of diseased tissue. 25 figs.

Horn, K.M.; Doyle, B.L.

1996-08-20T23:59:59.000Z

492

The Economics of Interchange Fees and Their Regulation: An Overview  

E-Print Network [OSTI]

This essay surveys the economic literature on interchange fees and the debate over whether interchange should be regulated and, if so, how. We consider, first, the operation of unitary payment systems, like American Express, ...

Evans, David

2005-07-08T23:59:59.000Z

493

U.S. Department of Defense's Rebates and Incentives Regulations  

Broader source: Energy.gov [DOE]

Presentation—given at the Spring 2009 Federal Utility Partnership Working Group (FUPWG) meeting—covers the U.S. Department of Defense's (DoD's) statuatory authority and financial management regulation for rebates and incentives.

494

Market-Based Emissions Regulation and Industry Dynamics  

E-Print Network [OSTI]

We assess the long-run dynamic implications of market-based regulation of carbon dioxide emissions in the US Portland cement industry. We consider several alternative policy designs, including mechanisms that use production ...

Fowlie, Meredith

495

Minimum Purchase Price Regulations (Prince Edward Island, Canada)  

Broader source: Energy.gov [DOE]

The Minimum Purchase Price Regulations establish the price which utilities must pay for power produced by large-scale renewable energy generators – that is those capable of producing more than 100...

496

Ena/VASP Proteins Regulate Cortical Neuronal Positioning  

E-Print Network [OSTI]

Development of the multilayered cerebral cortex involves extensive regulated migration of neurons arising from the deeper germinative layers of the mammalian brain [1]. The anatomy and formation of the cortical layers has ...

Goh, Keow Lin

497

Negotiated Regulation, Implementation and Compliance in the United States  

E-Print Network [OSTI]

Interest in the use of so-called voluntary approaches to supplement or replace formal environmental regulation is on the rise, both in Europe and in the United States. These approaches fall into two general categories: (1) ...

Ashford, Nicholas

2007-01-01T23:59:59.000Z

498

Effective Regulatory Institutions: The Regulator's Role in the...  

Open Energy Info (EERE)

may be regarded by others, and (3) the issue of independence of regulation from undue political intervention. LEDSGP green logo.png This tool is included in the Transportation...

499

ANALYSIS AND CHARACTERIZATION OF A PROGRAMMABLE LOW-DROPOUT REGULATOR  

E-Print Network [OSTI]

As portable electronic devices become a part of daily life, it creates a huge market for electronic components for those battery driven devices. Low-dropout (LDO) voltage regulator is an important part that provides steady DC supplies for other...

Qiu, Xiaofan

2007-09-17T23:59:59.000Z

500

Stability issues in IC Low Drop Out voltage regulators  

E-Print Network [OSTI]

Performance issues of IC Low Drop Out (LDO) voltage regulators, with specific reference to stability, are discussed in this thesis. Evaluation of existing frequency compensation schemes and their performances across operating loads is presented...

Chava, Krishna Chaitanya

2002-01-01T23:59:59.000Z