Sample records for underlying controlling biological

  1. Uncertainty in synthetic biology for release and possibilities for regulation under the Toxic Substances Control Act

    E-Print Network [OSTI]

    Lightfoot, Shlomiya

    2014-01-01T23:59:59.000Z

    The emerging field of synthetic biology is developing rapidly and promises diverse applications. Many anticipated applications, particularly those involving release of engineered microbes into the environment or human ...

  2. BIOLOGICAL AND MICROBIAL CONTROL Potential of Entomopathogenic Nematodes for Biological Control of

    E-Print Network [OSTI]

    nematodes, biological control, cucumber BLACK PLASTIC MULCH and drip or trickle irrigation). Drip irrigation, installed simulta- neously under the plastic mulch, uses less water than conventional is concentrated around the base of the plants (Orzolek et al. 1996). Used in combination, black plastic mulch

  3. SPECIAL ISSUE ON SYSTEMS BIOLOGY, JANUARY 2008 51 Stochastic Modeling and Control of Biological

    E-Print Network [OSTI]

    Pappas, George J.

    of modeling, abstraction, and control of a biological system, namely, the lactose regulation systemSPECIAL ISSUE ON SYSTEMS BIOLOGY, JANUARY 2008 51 Stochastic Modeling and Control of Biological for stochastic modeling, model abstraction, and controller design for a biological system. The first half

  4. Qubit dynamics under alternating controls

    E-Print Network [OSTI]

    Aiello, Clarice Demarchi

    2014-01-01T23:59:59.000Z

    In this thesis, we discuss two problems of quantum dynamics in the presence of alternating controls. Alternating controls arise in many protocols designed to extend the duration over which a qubit is a useful computational ...

  5. AN INTEGRATED BIOLOGICAL CONTROL SYSTEM AT HANFORD

    SciTech Connect (OSTI)

    JOHNSON AR; CAUDILL JG; GIDDINGS RF; RODRIGUEZ JM; ROOS RC; WILDE JW

    2010-02-11T23:59:59.000Z

    In 1999 an integrated biological control system was instituted at the U.S. Department of Energy's Hanford Site. Successes and changes to the program needed to be communicated to a large and diverse mix of organizations and individuals. Efforts at communication are directed toward the following: Hanford Contractors (Liquid or Tank Waste, Solid Waste, Environmental Restoration, Science and Technology, Site Infrastructure), General Hanford Employees, and Hanford Advisory Board (Native American Tribes, Environmental Groups, Local Citizens, Washington State and Oregon State regulatory agencies). Communication was done through direct interface meetings, individual communication, where appropriate, and broadly sharing program reports. The objectives of the communication efforts was to have the program well coordinated with Hanford contractors, and to have the program understood well enough that all stakeholders would have confidence in the work performed by the program to reduce or elimated spread of radioactive contamination by biotic vectors. Communication of successes and changes to an integrated biological control system instituted in 1999 at the Department of Energy's Hanford Site have required regular interfaces with not only a diverse group of Hanford contractors (i.e., those responsible for liquid or tank waste, solid wastes, environmental restoration, science and technology, and site infrastructure), and general Hanford employees, but also with a consortium of designated stake holders organized as the Hanford Advisory Board (i.e., Native American tribes, various environmental groups, local citizens, Washington state and Oregon regulatory agencies, etc.). Direct interface meetings, individual communication where appropriate, and transparency of the biological control program were the methods and outcome of this effort.

  6. Dynamic control of catalysis within biological cells

    E-Print Network [OSTI]

    Biman Jana; Biman Bagchi

    2011-05-26T23:59:59.000Z

    We develop a theory of enzyme catalysis within biological cells where the substrate concentration [S](t) is time dependent, in contrast to the Michaelis-Menten theory that assumes a steady state. We find that the time varying concentration can combine, in a non-linear way, with the ruggedness of the free energy landscape of enzymes (discovered both in single molecule studies and in simulations) to provide a highly efficient switch (or, bifurcation) between two catalytically active states, at a critical substrate concentration. This allows a dynamic control of product synthesis in cell.

  7. Electric Drive Vehicle Level Control Development Under Various...

    Broader source: Energy.gov (indexed) [DOE]

    Compo. Validate Standalone validation Under different temperature conditions (hotcold) Vehicle Control Supervisory controller Vehicle Validate Under different...

  8. Controlling biological systems: the lactose regulation system of Escherichia coli

    E-Print Network [OSTI]

    Pappas, George J.

    Controlling biological systems: the lactose regulation system of Escherichia coli A. Agung Julius hybrid model of the lactose regulation system of E. coli bacteria that capture important phenomena which In this paper we present a framework that consists of modeling, abstraction and control of a biological system

  9. Optimal control for biological movement systems

    E-Print Network [OSTI]

    Li, Weiwei

    2006-01-01T23:59:59.000Z

    Kalman. When is a linear control system optimal? Journal ofOptimal stationary control of linear systems with control-J. Mclane. Optimal stochastic control of linear systems with

  10. BIOLOGICAL AND MICROBIAL CONTROL Biology and Rearing of Cleruchoides noackae (Hymenoptera

    E-Print Network [OSTI]

    : Mymaridae), an Egg Parasitoid for the Biological Control of Thaumastocoris peregrinus (Hemiptera egg para- sitoid of Thaumastocoris peregrinus Carpintero and Dellape´ (Hemiptera: Thaumastocoridae peregrinus Carpintero and Dellape´ (Hemiptera: Thaumastocoridae) is a se- rious and widespread pest

  11. Arms Control: US and International efforts to ban biological weapons

    SciTech Connect (OSTI)

    Not Available

    1992-12-01T23:59:59.000Z

    The Bacteriological (Biological) and Toxin Weapons Convention, the treaty that bans the development, production, and stockpiling and acquisition of biological weapons was opened for signature in 1972 and came into force in 1975 after being ratified by 22 governments, including the depository nations of the USA, the United Kingdom, and the former Soviet Union. In support of the Convention, the USA later established export controls on items used to make biological weapons. Further, in accordance with the 1990 President`s Enhanced Proliferation Control Initiative, actions were taken to redefine and expand US export controls, as well as to encourage multilateral controls through the Australia Group. Thus far, the Convention has not been effective in stopping the development of biological weapons. The principal findings as to the reasons of the failures of the Convention are found to be: the Convention lacks universality, compliance measures are effective, advantage of verification may outweigh disadvantages. Recommendations for mitigating these failures are outlined in this report.

  12. Characterization and Control of Biological Microrobots

    E-Print Network [OSTI]

    magnetic system is five orders-of-magnitude less than the propulsion force gener- ated by the flagellum proposed for propulsion: extracting energy from an ex- ternal magnetic field [4], or extracting energy from of Magnetotactic Bacterium (MTB) which can be considered as a biological microrobot. Magnetic dipole moment

  13. Selection of bioclimatically representative biological reserve systems under climate change

    E-Print Network [OSTI]

    Pyke, C R; Fischer, Douglas T

    2005-01-01T23:59:59.000Z

    of bioclimatically representative biological reserve systemsthat are bioclimatically representative across a range ofa ?at line (i.e. a representative sample of current climate

  14. Biology and Control of Floating Heart (Nymphoides cristata)

    E-Print Network [OSTI]

    Watson, Craig A.

    Biology and Control of Floating Heart (Nymphoides cristata) Leif Willey ­ University of Florida approaches ­ no accepted standard for control · Grass carp are not a viable option ­ Rapid spread in Lake · 3 soil types -L ake Toho (97% sand), -Orange Lake (77% O.M) -Potting soil mix · Highly fertile sand

  15. Fuzzy predictive control for nitrogen removal in biological wastewater treatment

    E-Print Network [OSTI]

    Fuzzy predictive control for nitrogen removal in biological wastewater treatment S. Marsili predictive control; wastewater treatment plant Introduction The problem of improving the nitrogen removal wastewater is too low, full denitrification is difficult to obtain and an additional source of organic carbon

  16. Neuropsychologia xxx (2005) xxxxxx Electrophysiological activity underlying inhibitory control

    E-Print Network [OSTI]

    2005-01-01T23:59:59.000Z

    Neuropsychologia xxx (2005) xxx­xxx Electrophysiological activity underlying inhibitory control. / Neuropsychologia xxx (2005) xxx­x

  17. Thermodynamics of quantum systems under dynamical control

    E-Print Network [OSTI]

    D. Gelbwaser-Klimovsky; Wolfgang Niedenzu; Gershon Kurizki

    2015-03-04T23:59:59.000Z

    In this review the debated rapport between thermodynamics and quantum mechanics is addressed in the framework of the theory of periodically-driven/controlled quantum-thermodynamic machines. The basic model studied here is that of a two-level system (TLS), whose energy is periodically modulated while the system is coupled to thermal baths. When the modulation interval is short compared to the bath memory time, the system-bath correlations are affected, thereby causing cooling or heating of the TLS, depending on the interval. In steady state, a periodically-modulated TLS coupled to two distinct baths constitutes the simplest quantum heat machine (QHM) that may operate as either an engine or a refrigerator, depending on the modulation rate. We find their efficiency and power-output bounds and the conditions for attaining these bounds. An extension of this model to multilevel systems shows that the QHM power output can be boosted by the multilevel degeneracy. These results are used to scrutinize basic thermodynamic principles: (i) Externally-driven/modulated QHMs may attain the Carnot efficiency bound, but when the driving is done by a quantum device ("piston"), the efficiency strongly depends on its initial quantum state. Such dependence has been unknown thus far. (ii) The refrigeration rate effected by QHMs does not vanish as the temperature approaches absolute zero for certain quantized baths, e.g., magnons, thous challenging Nernst's unattainability principle. (iii) System-bath correlations allow more work extraction under periodic control than that expected from the Szilard-Landauer principle, provided the period is in the non-Markovian domain. Thus, dynamically-controlled QHMs may benefit from hitherto unexploited thermodynamic resources.

  18. Fast, Cheap, and Under Control: Evaluating Revision Data Reliably Daghstuhl: Mining Programs and Processes Fast, Cheap and Under Control

    E-Print Network [OSTI]

    Godfrey, Michael W.

    release time Abram Hindle 5 #12;Fast, Cheap, and Under Control: Evaluating Revision Data ReliablyFast, Cheap, and Under Control: Evaluating Revision Data Reliably Daghstuhl: Mining Programs and Processes Fast, Cheap and Under Control: Evaluating Revision Data Reliably Abram Hindle, Michael W. Godfrey

  19. What is compost? Composting refers to biological decomposition and stabilization of organic materials by microorganisms under

    E-Print Network [OSTI]

    Mukhtar, Saqib

    What is compost? Composting refers to biological decomposition and stabilization of organic materials by microorganisms under aerobic conditions (in the presence of oxygen). During the composting is production of good-quality compost that is biologically stable, relatively uniform in appearance, free

  20. Mdp Optimal Control under Temporal Logic Constraints

    E-Print Network [OSTI]

    Ding, Xu Chu

    In this paper, we develop a method to automatically generate a control policy for a dynamical system modeled as a Markov Decision Process (MDP). The control specification is given as a Linear Temporal Logic (LTL) formula ...

  1. Optimal generation of entanglement under local control

    E-Print Network [OSTI]

    Raffaele Romano; Alessio Del Fabbro

    2007-07-11T23:59:59.000Z

    We study the optimal generation of entanglement between two qubits subject to local unitary control. With the only assumptions of linear control and unitary dynamics, by means of a numerical protocol based on the variational approach (Pontryagin's Minimum Principle), we evaluate the optimal control strategy leading to the maximal achievable entanglement in an arbitrary interaction time, taking into account the energy cost associated to the controls. In our model we can arbitrarily choose the relative weight between a large entanglement and a small energy cost.

  2. Electric Drive Vehicle Level Control Development Under Various...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Review 2014: Vehicle Level Model and Control Development and Validation Under Various Thermal Conditions Advanced Technology Vehicle Lab Benchmarking - Level 2 (in-depth)...

  3. Putting the Squeeze on Biology: Biomolecules Under Pressure

    ScienceCinema (OSTI)

    Sol Gruner

    2010-01-08T23:59:59.000Z

    Modest pressures encountered in the biosphere (i.e., below a few kbar) have extraordinary effects on biomembranes and proteins. These include pressure denaturation of proteins, dramatic changes in protein-protein association, substrate binding, membrane ion transport, DNA transcription, virus infectivity, and enzyme kinetics. Yet all of the biomaterials involved are highly incompressible. The challenge to the physicist is to understand the structural coupling between these effects and pressure to elucidate the relevant mechanisms. X-ray diffraction studies of membranes and proteins under pressure will be described. It is seen that it is not so much the magnitude of the changes, but rather the differential compressibilities of different parts of the structure that are responsible for effects.

  4. Topology Control Problems Under Symmetric and Asymmetric Power Thresholds

    E-Print Network [OSTI]

    Krumke, Sven O.

    Topology Control Problems Under Symmetric and Asymmetric Power Thresholds Sven O. Krumke1 , Rui Liu performance guarantees. Previous work on topology control has assumed the symmetric power thresh- old model, NY 12222. Email: rav i@cs . a l bany . edu. Abstract. We consider topology control problems where

  5. WILD PIGS: BIOLOGY, DAMAGE, CONTROL TECHINQUES AND MANAGEMENT

    SciTech Connect (OSTI)

    Mayer, John; Brisbin, I. Lehr

    2009-12-31T23:59:59.000Z

    The existence of problems with wild pigs (Sus scrofa) is nothing new to the Western Hemisphere. Damage by these introduced animals was reported as far back as 1505 by the early Spanish colonies in the Caribbean, where wild pigs were killing the colonists cattle. Droves of these animals also ravaged cultivated crops of maize and sugarcane on islands in the West Indies during this same time period. These wild pigs reportedly were very aggressive and often attacked Spanish soldiers hunting rebellious Indians or escaped slaves on these islands, especially when these animals were cornered. The documentation of such impacts by introduced populations of this species in the United States has subsequently increased in recent years, and continued up through the present (Towne and Wentworth. 1950, Wood and Barrett 1979, Mayer and Brisbin 1991, Dickson et al. 2001). In spite of a fairly constant history in this country since the early 1900s, wild pigs have had a dramatic recent increase in both distribution and numbers in the United States. Between 1989 and 2009, the number of states reporting the presence of introduced wild pigs went from 19 up to as many as 44. This increase, in part natural, but largely manmade, has caused an increased workload and cost for land and resource managers in areas where these new populations are found. This is the direct result of the damage that these introduced animals do. The cost of both these impacts and control efforts has been estimated to exceed a billion dollars annually (Pimentel 2007). The complexity of this problem has been further complicated by the widespread appeal and economic potential of these animals as a big game species (Tisdell 1982, Degner 1989). Wild pigs are a controversial problem that is not going away and will likely only get worse with time. Not only do they cause damage, but wild pigs are also survivors. They reproduce at a rate faster than any other mammal of comparable size, native or introduced; they can eat just about anything; and, they can live just about anywhere. On top of that, wild pigs are both very difficult to control and, with the possible exception of island ecosystems, almost impossible to eradicate (Dickson et al. 2001, Sweeney et al. 2003). The solution to the wild pig problem has not been readily apparent. The ultimate answer as to how to control these animals has not been found to date. In many ways, wild pigs are America's most successful large invasive species. All of which means that wild pigs are a veritable nightmare for land and resource managers trying to keep the numbers of these animals and the damage that they do under control. Since the more that one knows about an invasive species, the easier it is to deal with and hopefully control. For wild pigs then, it is better to 'know thy enemy' than to not, especially if one expects to be able to successfully control them. In an effort to better 'know thy enemy,' a two-day symposium was held in Augusta, Georgia, on April 21-22, 2004. This symposium was organized and sponsored by U.S.D.A. Forest Service-Savannah River (USFS-SR), U. S. Department of Energy-Savannah River Operations Office (DOE-SR), the Westinghouse Savannah River Company (WSRC), the South Carolina Chapter of the Soil & Water Conservation Society, and the Savannah River Ecology Laboratory (SREL). The goal of this symposium was to assemble researchers and land managers to first address various aspects of the biology and damage of wild pigs, and then review the control techniques and management of this invasive species. The result would then be a collected synopsis of what is known about wild pigs in the United States. Although the focus of the symposium was primarily directed toward federal agencies, presenters also included professionals from academic institutions, and private-sector control contractors and land managers. Most of the organizations associated with implementing this symposium were affiliated with the Savannah River Site (SRS), a 803 km{sup 2} federal nuclear facility, located in western South Carolina along the Savannah

  6. Control and estimation problems under partially nested information pattern

    E-Print Network [OSTI]

    Gattami, Ather Said

    In this paper we study distributed estimation and control problems over graphs under partially nested information patterns. We show a duality result that is very similar to the classical duality result between state ...

  7. Optimal Control of a Continuous Distillation Process under Probabilistic Constraints

    E-Print Network [OSTI]

    Henrion, René

    Optimal Control of a Continuous Distillation Process under Probabilistic Constraints René Henrion1 Universität Berlin, Germany Abstract A continuous distillation process with random inflow rate is considered model including the dynamics of the distillation process and proba- bilistic constraints under different

  8. An Optimal Control Approach to Cancer Treatment under Immunological Activity

    E-Print Network [OSTI]

    Ledzewicz, Urszula

    An Optimal Control Approach to Cancer Treatment under Immunological Activity Urszula Ledzewicz Mathematical models for cancer treatment that include immunological activity are con- sidered as an optimal. For various growth models on the cancer cells the existence and optimality of singular controls

  9. For many of these pests biological control is the best,if not the only,option for control.However,biological control

    E-Print Network [OSTI]

    and greenhouse,three laboratories,numerous growth rooms and walk-in cold storage facilities. In addition of new pests, means that the forestry industry needs significant capacity in this field.The Tree Protection Cooperative Programme (TPCP) provides the industry with support for the biological control

  10. A passivity-based controller under low sampling for speed control of PMSM

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    A passivity-based controller under low sampling for speed control of PMSM M. Khanchoul a , M: Permanent magnet synchronous motor (PMSM) Sampled-data control Port-controlled Hamiltonian systems IDA. All rights reserved. 1. Introduction Nowadays, PMSM is used in many fields. This gain in popularity

  11. Mitochondrial DNA diversity of Cleruchoides noackae (Hymenoptera: Mymaridae): a potential biological control

    E-Print Network [OSTI]

    biological control agent for Thaumastocoris peregrinus (Hemiptera: Thaumastocoridae) R. L. Nadel · M. J Control (IOBC) 2011 Abstract Thaumastocoris peregrinus Carpintero and Dellape´ (Hemiptera parasitoid Á Hemiptera Á Hymenoptera Á Laboratory rearing Á Mymaridae Á Thaumastocoridae Introduction

  12. Optimal control of a gasolinefueled car engine under pollution constraint

    E-Print Network [OSTI]

    Bonnans, Frédéric

    Optimal control of a gasoline­fueled car engine under pollution constraint J. Fr'ed'eric Bonnans was introduced in order to decrease fuel consumption. This technology, called ``lean­burn engine'', uses an air­fuel mixture which contains less fuel than in a classical engine. The air­fuel mixture of an engine

  13. Optimal Control of Residential Energy Storage Under Price Fluctuations

    E-Print Network [OSTI]

    Optimal Control of Residential Energy Storage Under Price Fluctuations Peter van de ven Department.hegde,laurent.massoulie,theodoros.salonidis}@technicolor.com Abstract--An increasing number of retail energy markets exhibit price fluctuations and provide home users the oppor- tunity to buy energy at lower than average prices. However, such cost savings are hard to realize

  14. Motivation to study security of control systems. Our Results/Contribution. Summary. Security constrained control under

    E-Print Network [OSTI]

    Hu, Fei

    . Research challenges. Investigate realistic models of attacks to control systems from the "systemsMotivation to study security of control systems. Our Results/Contribution. Summary. Security constrained control under denial-of-service attacks. Saurabh Amin1 Alvaro Cárdenas2 Alexandre Bayen1 Shankar

  15. Spin system trajectory analysis under optimal control pulses

    E-Print Network [OSTI]

    Ilya Kuprov

    2012-12-18T23:59:59.000Z

    Several methods are proposed for the analysis, visualization and interpretation of high-dimensional spin system trajectories produced by quantum mechanical simulations. It is noted that expectation values of specific observables in large spin systems often feature fast, complicated and hard-to-interpret time dynamics and suggested that populations of carefully selected subspaces of states are much easier to analyze and interpret. As an illustration of the utility of the proposed methods, it is demonstrated that the apparent "noisy" appearance of many optimal control pulses in NMR and EPR spectroscopy is an illusion - the underlying spin dynamics is shown to be smooth, orderly and very tightly controlled.

  16. Oxygen as a control on seafloor biological communities and their roles in sedimentary carbon cycling

    E-Print Network [OSTI]

    Oxygen as a control on seafloor biological communities and their roles in sedimentary carbon experiments were conducted at sites spanning the steep oxygen, organic matter, and biological community gradients across the Arabian Sea oxygen minimum zone, in order to quantify the role that fauna play

  17. Breaking news: Biological control agent for Thaumastocoris peregrinus to be released in South Africa

    E-Print Network [OSTI]

    milestone in terms of ensuring sustainable plantation forestry in South Africa was safe to release in South Africa as a biological control agent. The release strategy for C. noackae in South Africa must still be finalized. But

  18. Controlled polymer synthesis--from biomimicry towards synthetic biology

    E-Print Network [OSTI]

    Davis, Ben G.

    . In particular, he develops competitive search methodologies and intelligent decision support systems over lengthscales ranging from a few nm to several microns is generating systems that not only begin and soft materials for synthetic biology. He is currently a research associate at IESL-FORTH, Heraklion

  19. Interactions between Two Biological Control Agents and an Herbicide for

    E-Print Network [OSTI]

    Maxwell, Bruce D.

    biomass, root biomass, and shoot number, the integration of more than one control method would have States, Canada (Moore 1975), and northern Europe (Rydberg and Milberg 2000). In the Southern Hemisphere

  20. Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625govInstrumentstdmadapInactiveVisiting the TWP TWPAlumniComplexMaterialProductionBiological andU.S.Biology

  1. Biologic

    E-Print Network [OSTI]

    Louis H. Kauffman

    2002-04-03T23:59:59.000Z

    In this paper we explore the boundary between biology and the study of formal systems (logic). In the end, we arrive at a summary formalism, a chapter in "boundary mathematics" where there are not only containers but also extainers >protein folding and the basic structure of the Temperley Lieb algebra at the foundations of topological invariants of knots and links.

  2. The establishment, biological success and host impact of Diorhabda elongata, imported biological control agents of invasive Tamarix in the United States

    E-Print Network [OSTI]

    Hudgeons, Jeremy L.

    2009-05-15T23:59:59.000Z

    Diorhabda elongata elongata leaf beetles were released at two field locations in the upper Colorado River watershed of Texas in 2003 and 2004 for the biological control of invasive Tamarix, exotic trees deteriorating riparian ecosystems of western...

  3. 14 Climate control of biological UV exposure in polar and alpine aquatic ecosystems

    E-Print Network [OSTI]

    Vincent, Warwick F.

    + ) = the incident solar irradiance in relative energy units; F = factor modifying that flux as a function of ozone14 Climate control of biological UV exposure in polar and alpine aquatic ecosystems Warwick F in these ecosystems may also be more vulnerable to UV toxicity because of the inhibiting effects of cold tempera

  4. BIOLOGICAL AND MICROBIAL CONTROL Host Range Testing of Tamarixia radiata (Hymenoptera: Eulophidae)

    E-Print Network [OSTI]

    Hoddle, Mark S.

    ) Sourced From the Punjab of Pakistan for Classical Biological Control of Diaphorina citri (Hemiptera citrus psyllid, Diaphorina citri Kuwayama (Hemiptera: Liviidae), sourced from the Punjab of Pakistan 2008, Asian citrus psyllid, Diaphorina citri Kuwayama (Hemiptera: Liviidae), was detected for the Þrst

  5. Boundary control for an industrial under-actuated tubular chemical reactor

    E-Print Network [OSTI]

    Boundary control for an industrial under-actuated tubular chemical reactor D. Del Vecchio a , N and studied for an industrial under-actuated tubular chemical reactor. This work presents a case-study of the performance of a decentralized versus centralized control strategy. The tubular reactor under consideration

  6. Do You Have Adequate Staffing to Keep Costs Under Control?

    E-Print Network [OSTI]

    Mergens, E. H.

    Competitive pressures have forced companies to seek reduced costs through reduced staffing. The emphasis has been on fixed cost control at the expense of some loss in variable cost control. Restructuring through reduced staffing has some pitfalls...

  7. MinMax Control of LQ Systems under the H1 Norm Constraint

    E-Print Network [OSTI]

    Ito, Satoshi

    ** Abstract: Satisfactory optimal control of linear systems under the existence of distur­ bance is studiedMin­Max Control of LQ Systems under the H1 Norm Constraint Kiyotaka Shimizu* and Satoshi Ito. The satisfactory optimal control minimizes a quadratic maximal­valued objective functional subject to the H1 norm

  8. An Optimal Resource Control Scheme under Fidelity and Energy Constraints in Sensor Networks

    E-Print Network [OSTI]

    Zhang, Yanyong

    1 An Optimal Resource Control Scheme under Fidelity and Energy Constraints in Sensor Networks control under the fidelity and energy constraints, we present a resource increase and decrease algorithm networks, Resource control, Fidelity, Energy efficiency I. INTRODUCTION As the technologies in MEMS

  9. Searching for quantum optimal controls under severe constraints

    E-Print Network [OSTI]

    Gregory Riviello; Katharine Moore Tibbetts; Constantin Brif; Ruixing Long; Re-Bing Wu; Tak-San Ho; Herschel Rabitz

    2015-02-03T23:59:59.000Z

    The success of quantum optimal control for both experimental and theoretical objectives is connected to the topology of the corresponding control landscapes, which are free from local traps if three conditions are met: (1) the quantum system is controllable, (2) the Jacobian of the map from the control field to the evolution operator is of full rank, and (3) there are no constraints on the control field. This paper investigates how the violation of assumption (3) affects gradient searches for globally optimal control fields. The satisfaction of assumptions (1) and (2) ensures that the control landscape lacks fundamental traps, but certain control constraints can still introduce artificial traps. Proper management of these constraints is an issue of great practical importance for numerical simulations as well as optimization in the laboratory. Using optimal control simulations, we show that constraints on quantities such as the number of control variables, the control duration, and the field strength are potentially severe enough to prevent successful optimization of the objective. For each such constraint, we show that exceeding quantifiable limits can prevent gradient searches from reaching a globally optimal solution. These results demonstrate that careful choice of relevant control parameters helps to eliminate artificial traps and facilitate successful optimization.

  10. CONTROLLER TUNING FREEDOM UNDER PLANT IDENTIFICATION UNCERTAINTY: DOUBLE YOULA BEATS

    E-Print Network [OSTI]

    Van den Hof, Paul

    Onderzoek (NWO)'. C G0· ·· Õ¹ ¹ ¹ ¹ ¹ r1 r2 u y Fig. 1. Feedback interconnection H´G0 Cµ. which maps of a nominal model and some norm-bounded model or parameter un- certainty. See e.g. (Ninness and Goodwin, 1995 the control design step is a robust control design optimizing the worst-case performance cost

  11. Online regulations of low order systems under bounded control

    E-Print Network [OSTI]

    Arora, Sumit

    2004-09-30T23:59:59.000Z

    Time-optimal solutions provide us with the fastest means to regulate a system in presence of input constraints. This advantage of time-optimal control solutions is offset by the fact that their real-time implementation involves computationally...

  12. The biological control of brown soft scale Coccus hesperidum L. (Homoptera: Coccidae) in interior plantscapes

    E-Print Network [OSTI]

    Stauffer, Robert Stevens

    1996-01-01T23:59:59.000Z

    underway. I would also like to thank Texas Instruments, 3M Corporanon, and the Conroe Elementary School District for allowing their interior plantscapes to be used as research sites. And finally, thanks to the San Antonio Botanical Gardens, for giving me.... BIOLOGICAL CONTROL UTILIZING METAPHYCUS ALBERTI(HOWARD) . . . . . 56 Introduction . Materials and Methods. Site Selection. Site Preparation and Sampling Methods Introduction of Parasites and Measurement Intervals . . . Results...

  13. Economic Implications of Biological Control of Arundo donax in the Texas Rio Grande Basin

    E-Print Network [OSTI]

    Seawright, Emily; Rister, M. Edward; Lacewell, Ronald; McCorkle, Dean; Sturdivant, Allen; Goolsby, John; Yang, Chenghai; Harris, B.L.

    , TX. 3 Texas AgriLife Extension Service, College Station, TX. 4 Texas A&M University, Agricultural Research and Extension Center, Weslaco, TX. 5 United States Department of Agriculture-Agricultural Research Service, Weslaco, TX. 6 Texas Water... Resources Institute, College Station, TX Texas Water Resources Institute Technical Report No. 358 Texas A&M University System College Station, Texas 77843-2118 November 2009 TR-358 November 2009 Economic Implications of Biological Control...

  14. Quantum Information Processing with Delocalized Qubits under Global Control

    E-Print Network [OSTI]

    Joseph Fitzsimons; Li Xiao; Simon C. Benjamin; Jonathan A. Jones

    2006-06-22T23:59:59.000Z

    Any technology for quantum information processing (QIP) must embody within it quantum bits (qubits) and maintain control of their key quantum properties of superposition and entanglement. Typical QIP schemes envisage an array of physical systems, such as electrons or nuclei, with each system representing a given qubit. For adequate control, systems must be distinguishable either by physical separation or unique frequencies, and their mutual interactions must be individually manipulable. These difficult requirements exclude many nanoscale technologies where systems are densely packed and continuously interacting. Here we demonstrate a new paradigm: restricting ourselves to global control pulses we permit systems to interact freely and continuously, with the consequence that qubits can become delocalized over the entire device. We realize this using NMR studies of three carbon-13 nuclei in alanine, demonstrating all the key aspects including a quantum mirror, one- and two-qubit gates, permutation of densely packed qubits and Deutsch algorithms.

  15. Towards Biological Control of Kudzu Through an Improved Understanding of Insect-Kudzu Interactions

    SciTech Connect (OSTI)

    Orr, D.; Barber, G.; DeBarr, G.; Thornton, M.

    2001-08-03T23:59:59.000Z

    The authors evaluated various approaches to the biological control of kudzu and exotic weed that infests the SRS. A large number of native pollinators were found to be attracted to kudzu. The viability of seed was found to be low, between 2% and 11%. This is the result of native Hemiptera. The results suggest that seed feeding insects should not be targeted for importation. Both kudzu and soybeans had the same level of abundance and diversity of herbivore insects and the same levels of defoliation. No vine or root damaging species were found. Efforts should be targeted to the latter insects to control kudzu.

  16. Linear Feedback Control Input under Actuator Saturation: a Takagi-Sugeno Approach

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Linear Feedback Control Input under Actuator Saturation: a Takagi-Sugeno Approach Souad Bezzaoucha into account the effect of saturation throughout the design procedure, a controller that may be linear. The third strategy is a two-step approach in which a nominal linear controller is first constructed

  17. Design of penalty functions for optimal control of linear dynamical systems under state and input constraints

    E-Print Network [OSTI]

    Design of penalty functions for optimal control of linear dynamical systems under state and input of solving a constrained optimal control for a general single-input single output linear time varying system dimensional (functional optimization) case. The main novelty is that both the bounds on the control variable

  18. A Dynamic Inventory Control Policy Under Demand, Yield and Lead Time Uncertainties

    E-Print Network [OSTI]

    Boyer, Edmond

    A Dynamic Inventory Control Policy Under Demand, Yield and Lead Time Uncertainties Mohamed Zied@lgi.ecp.fr, dallery@lgi.ecp.fr) ABSTRACT In this paper, we analyze a single-stage and single-item inventory control it. Keywords: inventory control, forecasts, cycle service level, fill rate, safety stock, policy

  19. Interference Mitigation via Power Control under the One-Power-Zone Constraint

    E-Print Network [OSTI]

    Yu, Wei

    Interference Mitigation via Power Control under the One-Power-Zone Constraint Hayssam Dahrouj, Wei on different zones. The objective of this paper is to design power control strategies to mitigation inter this constrained power control problem based on an iterative function evaluation technique. The proposed algorithms

  20. Learning Multiple Models of Non-Linear Dynamics for Control under Varying Contexts

    E-Print Network [OSTI]

    Vijayakumar, Sethu

    Learning Multiple Models of Non-Linear Dynamics for Control under Varying Contexts Georgios Petkos for adaptive motor control exist which learn the system's inverse dynamics online and use this single model;II Command Context 1 Context 2 Dynamics models Context n Control Learning Commands Switch / Mix

  1. Learning Multiple Models of Non-Linear Dynamics for Control under Varying Contexts

    E-Print Network [OSTI]

    Toussaint, Marc

    Learning Multiple Models of Non-Linear Dynamics for Control under Varying Contexts Georgios Petkos for adaptive motor control exist which learn the system's inverse dynamics online and use this single model version - to appear in ICANN 2006 #12;II Command Context 1 Context 2 Dynamics models Context n Control

  2. Classical biological control of Mediterranean fruit fly, Ceratitis capitata (Wiedemann), (Diptera:Tephritidae): natural enemy exploration and nontarget testing

    E-Print Network [OSTI]

    Trostle Duke, Marcia Katherine

    2006-08-16T23:59:59.000Z

    This work covers stages one through seven (of nine stages) of a classical biological control program for Mediterranean fruit fly (=medfly), Ceratitis capitata (Wiedemann). Major research objectives concentrate on stage five (exploration...

  3. Queue and Power Control for Rechargeable Sensor Networks under SINR Interference Model

    E-Print Network [OSTI]

    Koksal, Can Emre

    Queue and Power Control for Rechargeable Sensor Networks under SINR Interference Model Zhoujia Mao buffers to maximize the throughput with renewable energy sources under protocol interference model@ece.osu.edu Abstract--Renewable energy sources can be attached to sensor nodes to substantially improve the performance

  4. USE OF GCLS TO CONTROL LEAKAGE THROUGH GEOMEMBRANE DEFECTS UNDER HIGH HYDRAULIC HEADS

    E-Print Network [OSTI]

    Zornberg, Jorge G.

    USE OF GCLS TO CONTROL LEAKAGE THROUGH GEOMEMBRANE DEFECTS UNDER HIGH HYDRAULIC HEADS Christine T liners under conditions representative of dams (i.e., high hydraulic heads). Specifically, the objective of interface contact, hydraulic head, and GCL hydration procedures on the leakage rate were considered

  5. Optimal Control of Multi-Vehicle-Systems Under Communication Constraints Using Mixed-Integer

    E-Print Network [OSTI]

    Stryk, Oskar von

    Optimal Control of Multi-Vehicle-Systems Under Communication Constraints Using Mixed-Integer Linear Programming Christian Reinl and Oskar von Stryk Simulation, Systems Optimization and Robotics Group Technische" (Athens, Greece, October 15 - 17, 2007) Abstract-- A new planning method for optimal cooperative control

  6. Networked Control Systems under Cyber Attacks with Applications to Power Networks

    E-Print Network [OSTI]

    Johansson, Karl Henrik

    Terms-- Networked Control Systems, Fault Detection, Power Systems I. INTRODUCTION Several infrastructure infrastructure systems are vulnerable to cyber attacks [1], [2], which are performed on the information residingNetworked Control Systems under Cyber Attacks with Applications to Power Networks Andr´e Teixeira

  7. Impacts of Control and Communication System Vulnerabilities on Power Systems Under

    E-Print Network [OSTI]

    Hayat, Majeed M.

    1 Impacts of Control and Communication System Vulnerabilities on Power Systems Under Contingencies, NM, USA Abstract--Modern power grids rely heavily on their control systems operating over and blackouts remain possible if the initial disturbances in the power grid are accompanied by other system

  8. Biological aspects and control of johnsongrass (Sorghum halepense (L.) Pers.) in grain sorghum (Sorghum bicolor (L.) Moench)

    E-Print Network [OSTI]

    Lopez, Juan Alberto

    1988-01-01T23:59:59.000Z

    BIOLOGICAL ASPECTS AND CONTROL OF JDH((SON(il(ASS (~S( ~ll (L. ( P . ] IN GRAIN SORGHUM [SorcOhum bicolor (L. ) Moench] A Thesis JUAN ALBERTO LOPEZ Submitted to the Graduate College of Texas ALM University in partial fulfillment... of the requirements for the degree of MASTER OF SCIENCE May 1988 Major Subject: Agronomy BIOLOGICAL ASPECTS AND CONTROL OF JDNNSDNGNSSS [~SD t~t t L. t P . ] IN GRAIN SORGHUM [~Sor hum bicolor (L. ) Moench] A Thesis JUAN ALBERTO LOPEZ Approved as to style...

  9. Bifurcation of Singular Arcs in an Optimal Control Problem for Cancer Immune System Interactions under Treatment

    E-Print Network [OSTI]

    Ledzewicz, Urszula

    , 63130-4899, hms@wustl.edu Abstract-- A mathematical model for cancer treatment that includesBifurcation of Singular Arcs in an Optimal Control Problem for Cancer Immune System Interactions under Treatment Urszula Ledzewicz Dept. of Mathematics and Statistics, Southern Illinois University

  10. Joint Power Control and Beamforming Codebook Design for MISO Channels under the Outage

    E-Print Network [OSTI]

    Yu, Wei

    Joint Power Control and Beamforming Codebook Design for MISO Channels under the Outage Criterion and beamforming codebooks for limited-feedback multiple-input single-output (MISO) wireless systems. The problem focuses on optimal design of single-user limited-feedback systems over multiple-input single-output (MISO

  11. CHANCE CONSTRAINED OPTIMAL POWER FLOW: RISK-AWARE NETWORK CONTROL UNDER UNCERTAINTY

    E-Print Network [OSTI]

    Bienstock, Daniel

    resulting in automatic line tripping to protect lines from thermal stress, a risky and undesirable outcome control sophistication and careful long-term planning. Nevertheless, the grid is under growing stress in the grid are largely of an engineering nature (i.e. the flywheel-directed generator response used to handle

  12. Minimax Control For Cyber-Physical Systems under Network Packet Scheduling Attacks

    E-Print Network [OSTI]

    Johansson, Karl Henrik

    Minimax Control For Cyber-Physical Systems under Network Packet Scheduling Attacks Yasser Shoukry. Unfortunately, this re- liance on networks also brings new security vulnerabilities for con- trol systems. We and distribute reprints for Governmental purposes notwith- standing any copyright notation thereon. The views

  13. Agricultural and Related Pest Control Applicator License Classifications under the Florida Department of

    E-Print Network [OSTI]

    Watson, Craig A.

    PI-59 Agricultural and Related Pest Control Applicator License Classifications under the Florida Department of Agriculture and Consumer Services (FDACS)1 Frederick M. Fishel2 1. This document is PI-59, one Gainesville, FL 32611. The Institute of Food and Agricultural Sciences (IFAS) is an Equal Opportunity

  14. Analysis and control of the thermal runaway of ceramic slab under microwave heating

    E-Print Network [OSTI]

    Sheen, Dongwoo

    Analysis and control of the thermal runaway of ceramic slab under microwave heating Changjun Liu of the dielectrics during microwave heating, in which there is a big jump of the steady-state temperature while the applied microwave power varies slightly. It hinders engineers in the applications of microwave heating

  15. CHANCE CONSTRAINED OPTIMAL POWER FLOW: RISK-AWARE NETWORK CONTROL UNDER UNCERTAINTY

    E-Print Network [OSTI]

    Bienstock, Daniel

    which compromises stability. Smart grid goals include a commitment to large penetration of highly and careful long-term planning, with only very rare disruptions. However, the grid is under growing stress generation (coal, gas and hy- dro plants) over control areas of transmission networks, can result in grid

  16. Scheduling Job Families on Non-Identical Parallel Machines under Run-To-Run Control Constraints

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    1 Scheduling Job Families on Non-Identical Parallel Machines under Run-To-Run Control Constraints A constraint on jobs of the same product, i.e. the time interval between two consecutive jobs of the same are presented for scheduling jobs on non-identical parallel machines with setup times. In semiconductor

  17. Modeling and Control of Aggregated Air Conditioning Loads Under Realistic Conditions

    SciTech Connect (OSTI)

    Chang, Chin-Yao; Zhang, Wei; Lian, Jianming; Kalsi, Karanjit

    2013-02-24T23:59:59.000Z

    Demand-side control is playing an increasingly important role in smart grid control strategies. Modeling the dynamical behavior of a large population of appliances is especially important to evaluate the effectiveness of various load control strategies. In this paper, a high accuracy aggregated model is first developed for a population of HVAC units. The model efficiently includes statistical information of the population, systematically deals with heterogeneity, and accounts for a second-order effect necessary to accurately capture the transient dynamics in the collective response. Furthermore, the model takes into account the lockout effect of the compressor in order to represent the dynamics of the system under control more accurately. Then, a novel closed loop load control strategy is designed to track a desired demand curve and to ensure a stable and smooth response.

  18. Monotonically convergent optimal control theory of quantum systems under a nonlinear interaction with the control field

    E-Print Network [OSTI]

    M. Lapert; R. Tehini; G. Turinici; D. Sugny

    2009-05-29T23:59:59.000Z

    We consider the optimal control of quantum systems interacting non-linearly with an electromagnetic field. We propose new monotonically convergent algorithms to solve the optimal equations. The monotonic behavior of the algorithm is ensured by a non-standard choice of the cost which is not quadratic in the field. These algorithms can be constructed for pure and mixed-state quantum systems. The efficiency of the method is shown numerically on molecular orientation with a non-linearity of order 3 in the field. Discretizing the amplitude and the phase of the Fourier transform of the optimal field, we show that the optimal solution can be well-approximated by pulses that could be implemented experimentally.

  19. Entanglement preservation for multilevel systems under non-ideal pulse control

    E-Print Network [OSTI]

    Xu, Z Y

    2010-01-01T23:59:59.000Z

    We investigate how to effectively preserve the entanglement between two noninteracting multilevel oscillators coupled to a common reservoir under non-ideal pulse control. A universal characterization using fidelity is developed for the behavior of the system based on Nakajima-Zwanzig projection operator technique. Our analysis includes the validity of the approximation method and the decoherence-suppression by the non-ideal pulse control. The power of our strategy for protecting entanglement is numerically tested, showing potential applications for quantum information processing.

  20. Entanglement preservation for multilevel systems under non-ideal pulse control

    E-Print Network [OSTI]

    Z. Y. Xu; M. Feng

    2010-05-18T23:59:59.000Z

    We investigate how to effectively preserve the entanglement between two noninteracting multilevel oscillators coupled to a common reservoir under non-ideal pulse control. A universal characterization using fidelity is developed for the behavior of the system based on Nakajima-Zwanzig projection operator technique. Our analysis includes the validity of the approximation method and the decoherence-suppression by the non-ideal pulse control. The power of our strategy for protecting entanglement is numerically tested, showing potential applications for quantum information processing.

  1. Power Smoothing and Limitation Control of a PMSG-Based Marine Current Turbine under Swell Waves

    E-Print Network [OSTI]

    Boyer, Edmond

    Power Smoothing and Limitation Control of a PMSG-Based Marine Current Turbine under Swell Waves la puissance maximale (MPPT) nécessiterait d'accélérer ou de décélérer fréquemment la turbine à par une turbine marine associée à un générateur synchrone à aimants permanents (GSAP). Un algorithme

  2. The yield of Amorphous Solids Under Stress Control at Low Temperatures

    E-Print Network [OSTI]

    Valery Ilyin; Itamar Procaccia; Carmel Shor; Murari Singh

    2015-04-21T23:59:59.000Z

    The yield of amorphous solids like metallic glasses under external stress was discussed asserting that it is related to the glass transition by increasing temperature, or that it can be understood using statistical theories of various sorts. Here we study the approach to stress-controlled yield and argue that neither assertions can be supported, at least at low temperatures. The yield of amorphous solids at low temperatures is a highly structured phenomenon, characterized by a specific series of mechanical instabilities, and having no similarity at all to fluidization by increased temperature, real or fictive. The series of instabilities followed by stress controlled yield at low but finite temperature protocols can be predicted by analyzing athermal quasi-static strain controlled protocols, making the latter highly relevant for the deep understanding of the mechanical properties of amorphous solids.

  3. affects inhibitory control: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    or few glomeruli, receive slowly Paris-Sud XI, Universit de 7 Inhibitory Control in Mind and Brain: The Mathematics and Neurophysiology of the Underlying Computation Biology...

  4. Direct power control of shunt active filter using high selectivity filter (HSF) under distorted or unbalanced conditions

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    4 Direct power control of shunt active filter using high selectivity filter (HSF) under distorted.A. Djaffar) Abstract This paper describes the design of a new configuration of direct power control (DPC, Direct power control (DPC), Switching table, High selectivity filter, Distorted or unbalanced conditions

  5. Method and apparatus for single-stepping coherence events in a multiprocessor system under software control

    DOE Patents [OSTI]

    Blumrich, Matthias A. (Ridgefield, CT); Salapura, Valentina (Chappaqua, NY)

    2010-11-02T23:59:59.000Z

    An apparatus and method are disclosed for single-stepping coherence events in a multiprocessor system under software control in order to monitor the behavior of a memory coherence mechanism. Single-stepping coherence events in a multiprocessor system is made possible by adding one or more step registers. By accessing these step registers, one or more coherence requests are processed by the multiprocessor system. The step registers determine if the snoop unit will operate by proceeding in a normal execution mode, or operate in a single-step mode.

  6. Chance Constrained Optimal Power Flow: Risk-Aware Network Control under Uncertainty

    E-Print Network [OSTI]

    Bienstock, Daniel; Harnett, Sean

    2012-01-01T23:59:59.000Z

    When uncontrollable resources fluctuate, Optimum Power Flow (OPF), routinely used by the electric power industry to re-dispatch hourly controllable generation (coal, gas and hydro plants) over control areas of transmission networks, can result in grid instability, and, potentially, cascading outages. This risk arises because OPF dispatch is computed without awareness of major uncertainty, in particular fluctuations in renewable output. As a result, grid operation under OPF with renewable variability can lead to frequent conditions where power line flow ratings are significantly exceeded. Such a condition, which is borne by simulations of real grids, would likely resulting in automatic line tripping to protect lines from thermal stress, a risky and undesirable outcome which compromises stability. Smart grid goals include a commitment to large penetration of highly fluctuating renewables, thus calling to reconsider current practices, in particular the use of standard OPF. Our Chance Constrained (CC) OPF correct...

  7. WHAT IS COMPOST? Composting refers to the biological decomposition and stabilization of organic materials by microorganisms under

    E-Print Network [OSTI]

    Mukhtar, Saqib

    , good quality compost is produced that is biologically stable, relatively uniform in appearance, free as 10 to 20 times greater than that from agricultural lands. Research reports from academia, the EPA or topsoil blend to improve soil structure. Both practices help establish a protective vegetation cover

  8. Biology and chemical control of the sugarcane rootstock weevil, Anacentrinus deplanatus Csy., on grain sorghum

    E-Print Network [OSTI]

    Goode, J. P

    1960-01-01T23:59:59.000Z

    Tia. Iafersatiea Eertaiaisg te the iaseet's biology was ebtaiss4 by broakiag the-Eareffia seal, swjaratisg the tso ylaat parts, as4 observtag the saeeessive stages of ~ ef the iasect. Stalk seetieas were zoasseabls4 as4 reseale4 with aelte4 Laraffia after each...

  9. Predictive Control Algorithms Using Biological Signals for Active Relative Motion Canceling in

    E-Print Network [OSTI]

    Cavusoglu, Cenk

    @case.edu, cavusoglu@case.edu Abstract-- Robotics technology promises an enhanced way of performing off-pump coronary of the algorithm implemented on a 3-DOF robotic test-bed system are reported. I. INTRODUCTION Off-pump coronary). The earlier studies in the literature on canceling biological motion in robotic assisted medical interventions

  10. Feedback-based Information Roadmap (FIRM): Graph-based Estimation and Control of Robotic Systems Under Uncertainty

    E-Print Network [OSTI]

    Aghamohammadi, Aliakbar

    2014-05-07T23:59:59.000Z

    This dissertation addresses the problem of stochastic optimal control with imperfect measurements. The main application of interest is robot motion planning under uncertainty. In the presence of process uncertainty and imperfect measurements...

  11. Economic Incentives for Controlling Trade-Related Biological Invasions in the

    E-Print Network [OSTI]

    Lupi, Frank

    efforts focused on post-invasion control or eradication (Lupi, Hoehn, and Christie 2003). But there is now

  12. Biologically Inspired Kinematic Synergies Provide a New Paradigm for Balance Control of Humanoid

    E-Print Network [OSTI]

    Maass, Wolfgang

    be applied to balance control of humanoid robots. In contrast to existing approaches, this control strategy, and therefore cannot be applied in situations where the dynamic model of the robot may change online, due recent work on whole-body movements of humans [7], [8] shows that balance control and other human body

  13. In vitro colony interactions among species of trichoderma with inference toward biological control. Forest Service research paper

    SciTech Connect (OSTI)

    Reaves, J.L.; Crawford, R.H.

    1994-07-01T23:59:59.000Z

    Colony of interactions among 15 isolates representing seven species of Trichoderma were evaluated in vitro interactions characterized by zones of inhibition, demarcation lines, ridges of conidia, overgrowth, intermingling, anastomosis, and hyphal coiling in self-pairings and intraspecific and interspecific pairings of the seven species were recorded. Antagnostic interactions such as zones of inhibition were prevelent in these pairings. An understanding of the compatibility between species of isolates of Trichoderma will provide information on the use of multiple species of Trichoderma as biological control agents.

  14. Remote control and telescope auto-alignment system for multiangle LIDAR under development at CEILAP, Argentina

    E-Print Network [OSTI]

    Pallotta, Juan; Otero, Lidia; Chouza, Fernando; Raul, Delia; Gonzalez, Francisco; Etchegoyen, Alberto; Quel, Eduardo

    2013-01-01T23:59:59.000Z

    At CEILAP (CITEDEF-CONICET), a multiangle LIDAR is under development to monitor aerosol extinction coefficients in the frame of the CTA (Cherenkov Telescope Array) Project. This is an initiative to build the next generation of ground-based instruments to collect very high energy gamma-ray radiation (>10 GeV). The atmospheric conditions are very important for CTA observations, and LIDARs play an important role in the measurement of the aerosol optical depth at any direction. The LIDAR being developed at CEILAP was conceived to operate in harsh environmental conditions during the shifts, and these working conditions may produce misalignments. To minimize these effects, the telescopes comprising the reception unit are controlled by a self-alignment system. This paper describes the self-alignment method and hardware automation.

  15. Evidence for 2D Solitary Sound Waves in a Lipid Controlled Interface and its Biological Implications

    E-Print Network [OSTI]

    Shamit Shrivastava; Matthias F. Schneider

    2014-05-08T23:59:59.000Z

    Biological membranes by virtue of their elastic properties should be capable of propagating localized perturbations analogous to sound waves. However, the existence and the possible role of such waves in communication in biology remains unexplored. Here we report the first observations of 2D solitary elastic pulses in lipid interfaces, excited mechanically and detected by FRET. We demonstrate that the nonlinearity near a maximum in the susceptibility of the lipid monolayer results in solitary pulses that also have a threshold for excitation. These experiments clearly demonstrate that the state of the interface regulates the propagation of pulses both qualitatively and quantitatively. We elaborate on the striking similarity of the observed phenomenon to nerve pulse propagation and a thermodynamic basis of cell signaling in general.

  16. A Self-triggered Visual Servoing Model Predictive Control Scheme for Under-actuated Underwater Robotic Vehicles

    E-Print Network [OSTI]

    Dimarogonas, Dimos

    extensively used in the past for the autonomous operation of underwater robotic vehicles. Complex missions Robotic Vehicles Shahab Heshmati-Alamdari, Alina Eqtami, George C. Karras, Dimos V. Dimarogonas and Kostas Control (NMPC) scheme for an under- actuated underwater robotic vehicle. In this scheme, the control loop

  17. Growth control of the eukaryote cell: A systems biology study in yeast

    E-Print Network [OSTI]

    Castrillo, Juan I; Zeef, Leo A; Hoyle, David C; Zhang, Nianshu; Hayes, Andrew; Gardner, David C J; Cornell, Michael J; Petty, June; Hakes, Luke; Wardleworth, Leanne; Rash, Bharat; Brown, Marie; Dunn, Warwick B; Broadhurst, David; O'Donoghue, Kerry; Hester, Svenja S; Dunkley, Tom P J; Hart, Sarah; Swainston, Neil; Li, Peter; Gaskell, Simon J; Paton, Norman W; Lilley, Kathryn S; Kell, Douglas B; Oliver, Stephen G

    2007-04-30T23:59:59.000Z

    -line. At appropriate intervals, culture samples were collected for determination of biomass concentration. Biomass levels were monitored both spectrophotometrically at a wavelength of 600 nm, and by dry weight. Dry weight measurements were determined as described... , corresponding to the biological process: tRNA aminoacylation for protein translation (GO tool: GenMAPP). Colour code as in Fig. S17. Fig. S20. Storage vacuole. Groups of genes significantly up-regulated and down-regulated corresponding to the cellular...

  18. Pore-Scale Characterization of Biogeochemical Controls on Iron and Uranium Speciation under Flow Conditions

    SciTech Connect (OSTI)

    Pearce, Carolyn I.; Wilkins, Michael J.; Zhang, Changyong; Heald, Steve M.; Fredrickson, Jim K.; Zachara, John M.

    2012-09-17T23:59:59.000Z

    Etched silicon microfluidic pore network models (micromodels) with controlled chemical and redox gradients, mineralogy, and microbiology under continuous flow conditions are used for the incremental development of complex microenvironments that simulate subsurface conditions. We demonstrate the colonization of micromodel pore spaces by an anaerobic Fe(III)-reducing bacterial species (Geobacter sulfurreducens) and the enzymatic reduction of a bioavailable Fe(III) phase within this environment. Using both X-ray Microprobe and X-ray Absorption Spectroscopy, we investigate the combined effects of the precipitated Fe(III) phases and the microbial population on uranium biogeochemistry under flow conditions. Precipitated Fe(III) phases within the micromodel were most effectively reduced in the presence of an electron shuttle (AQDS), and Fe(II) ions adsorbed onto the precipitated mineral surface without inducing any structural change. In the absence of Fe(III), U(VI) was effectively reduced by the microbial population to insoluble U(IV), which was precipitated in discrete regions associated with biomass. In the presence of Fe(III) phases, however, both U(IV) and U(VI) could be detected associated with biomass, suggesting re-oxidation of U(IV) by localized Fe(III) phases. These results demonstrate the importance of the spatial localization of biomass and redox active metals, and illustrate the key effects of pore-scale processes on contaminant fate and reactive transport.

  19. Instrument for controlling the application of mechanical loads to biological and bicompatible test subjects

    DOE Patents [OSTI]

    Lintilhac, Phillip M. (Shelburne, VT); Vesecky, Thompson B. (Essex Junction, VT)

    1995-01-01T23:59:59.000Z

    Apparatus and methods are disclosed facilitating the application of forces and measurement of dimensions of a test subject. In one arrangement the test subject is coupled to a forcing frame and controlled forces applied thereto. Force applied to the test subject is measured and controlled. A dimensional characteristic of the test subject, such as growth, is measured by a linear variable differential transformer. The growth measurement data can be used to control the force applied. The transducer module receives force and dimensional data from the forcing frame. The transducer module is a separate, microprocessor-based unit that communicates the test data to a controller unit that controls the application of force to the test subject and receives the test data from the transducer module for force control, storage, and/or communication to the user.

  20. Instrument for controlling the application of mechanical loads to biological and bicompatible test subjects

    DOE Patents [OSTI]

    Lintilhac, P.M.; Vesecky, T.B.

    1995-09-19T23:59:59.000Z

    An apparatus and methods are disclosed facilitating the application of forces and measurement of dimensions of a test subject. In one arrangement the test subject is coupled to a forcing frame and controlled forces applied thereto. Force applied to the test subject is measured and controlled. A dimensional characteristic of the test subject, such as growth, is measured by a linear variable differential transformer. The growth measurement data can be used to control the force applied. The transducer module receives force and dimensional data from the forcing frame. The transducer module is a separate, microprocessor-based unit that communicates the test data to a controller unit that controls the application of force to the test subject and receives the test data from the transducer module for force control, storage, and/or communication to the user. 8 figs.

  1. Biology 494 Biology Internship

    E-Print Network [OSTI]

    Wurtele, Eve Syrkin

    Biology 494 Biology Internship Guidelines The Biology Program encourages students to seek out and participate in internship opportunities that have a clear biological focus. Internships may be arranged may receive credit in Biology 494 (Biology Internship) for participation in internships, regardless

  2. Motion Planning Under Uncertainty for Steerable Needles Real-time ControlMotivation LQG-based Planning and Control

    E-Print Network [OSTI]

    North Carolina at Chapel Hill, University of

    needle in 3D deformable tissue using a model-predictive controller (MPC), which steers the needle along 3-based Planning and Control Motion Planner Model Linearization LQG Controller Deformable Simulator Select high, and K. Goldberg. "Feedback Control For Steering Need Through 3D Deformable Tissue Using Helical Paths

  3. Biologically-Inspired Control Architecture for an Upper Limb, Intelligent Robotic Orthosis

    E-Print Network [OSTI]

    to activate the human muscles. The humanoid robot's muscles, actuated by pressure control, are controlled human motion and will facilitate a more human-friendly human-robot interaction. This leads to our illustration of applying the architecture to a proposed upper limb, robotic orthosis. Such an orthosis

  4. Optimal Control of Distributed Energy Resources and Demand Response under Uncertainty

    E-Print Network [OSTI]

    Siddiqui, Afzal

    2010-01-01T23:59:59.000Z

    Energy Resources and Demand Response under Uncertainty AfzalEnergy Resources and Demand Response under Uncertainty ?DER in conjunction with demand response (DR): the expected

  5. Faculty Expertise Index Advanced Artificial Intelligence, Technology, & Control Systems Development for Biological &

    E-Print Network [OSTI]

    Amin, S. Massoud

    Faculty Expertise Index Advanced Artificial Intelligence, Technology, & Control Systems Development-Paul Schirle-Keller Food Additives ­ Artificial Sweeteners ­ Ted Labuza Food Analysis Chromatographic Processing (see Phytochemicals, Advanced Artificial Intelligence) Canning Technology ­ Ted Labuza Cheese

  6. Tri-trophic Analyses of Rice, the Sugarcane Borer, and Putative Biological Control Agents

    E-Print Network [OSTI]

    Lv, Jiale

    2010-01-14T23:59:59.000Z

    . flavipes. Alam (1980) reported the introduction of C. flavipes and Lixophaga diatraeae (Townsend) (Diptera: Tachinidae), two larval parasitoids, succesfully reduced sugarcane borer injury to sub-economic levels in Barbados. The succesful control...

  7. The biology and control of the three-cornered alfalfa hopper Spissistilus festinus (Say)

    E-Print Network [OSTI]

    Jordan, Cedric Roy

    1952-01-01T23:59:59.000Z

    to Marshall et al (H9). Marshall and Gyrisco (US) reported that toxaphene was a good insecticide when used for meadow spittlebug control, but somewhat less effective than benzene hexachloride and dieldrin. Aldrin and parathion were not as satisfactory...

  8. Optimal Control of Distributed Energy Resources and Demand Response under Uncertainty

    E-Print Network [OSTI]

    Siddiqui, Afzal

    2010-01-01T23:59:59.000Z

    Rio de Janeiro, Brazil Optimal Control of Distributed EnergyRio de Janeiro, Brazil Optimal Control of Distributed EnergyRio de Janeiro, Brazil Optimal Control of Distributed Energy

  9. Assessment of Controlling Processes for Field-Scale Uranium Reactive Transport under Highly Transient Flow Conditions

    SciTech Connect (OSTI)

    Ma, Rui; Zheng, Chunmiao; Liu, Chongxuan; Greskowiak, Janek; Prommer, Henning; Zachara, John M.

    2014-02-13T23:59:59.000Z

    This paper presents the results of a comprehensive model-based analysis of a uranium tracer test conducted at the U.S Department of Energy Hanford 300 Area (300A) IFRC site. A three-dimensional multi-component reactive transport model was employed to assess the key factors and processes that control the field-scale uranium reactive transport. Taking into consideration of relevant physical and chemical processes, the selected conceptual/numerical model replicates the spatial and temporal variations of the observed U(VI) concentrations reasonably well in spite of the highly complex field conditions. A sensitivity analysis was performed to interrogate the relative importance of various processes and factors for reactive transport of U(VI) at the field-scale. The results indicate that multi-rate U(VI) sorption/desorption, U(VI) surface complexation reactions, and initial U(VI) concentrations were the most important processes and factors controlling U(VI) migration. On the other hand, cation exchange reactions, the choice of the surface complexation model, and dual-domain mass transfer processes, which were previously identified to be important in laboratory experiments, played less important roles under the field-scale experimental condition at the 300A site. However, the model simulations also revealed that the groundwater chemistry was relatively stable during the uranium tracer experiment and therefore presumably not dynamic enough to appropriately assess the effects of ion exchange reaction and the choice of surface complexation models on U(VI) sorption and desorption. Furthermore, it also showed that the field experimental duration (16 days) was not sufficiently long to precisely assess the role of a majority of the sorption sites that were accessed by slow kinetic processes within the dual domain model. The sensitivity analysis revealed the crucial role of the intraborehole flow that occurred within the long-screened monitoring wells and thus significantly affected both field-scale measurements and simulated U(VI) concentrations as a combined effect of aquifer heterogeneity and highly dynamic flow conditions. Overall, this study, which provides one of the few detailed and highly data-constrained uranium transport simulations, highlights the difference in controlling processes between laboratory and field scale that prevent a simple direct upscaling of laboratory-scale models.

  10. Optimal Control of Distributed Energy Resources and Demand Response under Uncertainty

    E-Print Network [OSTI]

    Siddiqui, Afzal

    2010-01-01T23:59:59.000Z

    Control of Distributed Energy Resources and Demand ResponseControl of Distributed Energy Resources and Demand Responseinstalled distribution energy resources (DER) in the form of

  11. A new control strategy to improve the performance of PWM ac to dc converter under unbalanced operating condition 

    E-Print Network [OSTI]

    Choudhury, Shamim A.

    1992-01-01T23:59:59.000Z

    A NEW CONTROL STRATEGY TO IMPROVE THE PERFORMANCE OF PWM AC TO DC CONVERTER UNDER UNBALANCED OPERATING CONDITION A Thesis by SHAMIM A. CHOUDHURY Submitted to the Office of Graduate Studies of Texas ARM University in partial fulfillment... of the requirements for the degree of MASTER 0 F S CIE'VCE t&fay 1992 Major Subject: Electrical Engineering A NEW CONTROL STRATEGY TO IMPROVE THE PERFORMANCE OF PWM AC TO DC CONVERTER UNDER UNBALANCED OPERATING CONDITION A Thesis by SHAMIM A. CHOUDHURY...

  12. Impact of interspecific interactions among parasitoids on inoculative biological control of leafminers attacking chrysanthemum

    E-Print Network [OSTI]

    Bader, Amy Elaine

    2007-09-17T23:59:59.000Z

    ................................................. x CHAPTER I INTRODUCTION..................................... 1 Introduction.................................... 1 I REPRODUCTIVE POTENTIAL AND HOST KIL ASESMENT OF DIGLYPHUS ISAEA ND ACNUSA SIBIRICA ON LIRIOMYZA LANGEI ATACKING... ....................................................................................................................... 86 ix LIST OF FIGURES FIGURE Page 1. Mean number of unparasitized dead leafminer larvae in the control, D. isaea, and D. sibirica cages.................................. 25 2. Mean number of parasitized leafminer larvae...

  13. Analysis of an Up/Down Power Control Algorithm for the CDMA Reverse Link under Fading #

    E-Print Network [OSTI]

    Mandayam, Narayan

    derive a stochastic nonlinear feedback con­ trol system model for the power controlled reverse link and study the power control performance based on the nonlinear model using the technique of statistical, Nonlinear Control, CDMA. 1 Introduction Power control is essential in CDMA systems to provide satisfactory

  14. Biological Control of Rhodesgrass Scale in Texas by Neodusmetia sangwani (Rao): Effectiveness and Colonization Studies.

    E-Print Network [OSTI]

    Schuster, Michael F.; Boling, J. C.

    1971-01-01T23:59:59.000Z

    . The potential number of parasites per stem was esti- mated by scale dissection. Release of one colony per mile was made, and colony spread and coalescence was evaluated in a pasture near Encino. The study showed that under the conditions of this test, 4... .----.----------.------------- 1 1 \\lol)ility of AT. sangzunni Females ----......-.------------ 12 ( olonv Spread in Grasslands -----.-.------------------------ 12 (, ,on)7 Establishment as Influenced by Yr~mber of Females Released \

  15. The biology and control of the southern corn rootworm Diabrotica undecimpunctata howardi Barber

    E-Print Network [OSTI]

    Daughdrill, Billy Hugh

    1958-01-01T23:59:59.000Z

    complete generation and sometimes a partial second in Nebraska, It was not until the advent of the chlorinated hydrocarbons that there was any effective insecticidal control of the southern porn root? worm, The early workers recommended various cultural... in Plate I s B. Immediately before each molt, the head cap? sule and anal shield are dark and considerably narrower than the body (Plate I, B, b, d, f,). Shortly after the larva hatches and infcnediately following each molt, the head and anal shield...

  16. Antinociceptive effects, metabolism and disposition of ketamine in ponies under target-controlled drug infusion

    SciTech Connect (OSTI)

    Knobloch, M. [Division Veterinary Pharmacology and Toxicology, University of Bern, 3012 Bern (Switzerland); Portier, C.J. [Environmental Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709 (United States); Levionnois, O.L. [Division Anesthesiology, Department of Clinical Veterinary Medicine, University of Bern 3012, Bern (Switzerland); Theurillat, R. [Department of Clinical Pharmacology, University of Bern, 3010 Bern (Switzerland); Thormann, W. [Department of Clinical Pharmacology, University of Bern, 3010 Bern (Switzerland); Spadavecchia, C. [Division Anesthesiology, Department of Clinical Veterinary Medicine, University of Bern 3012, Bern (Switzerland); Mevissen, M. [Division Veterinary Pharmacology and Toxicology, University of Bern, 3012 Bern (Switzerland)]. E-mail: meike.mevissen@vpi.unibe.ch

    2006-11-01T23:59:59.000Z

    Ketamine is widely used as an anesthetic in a variety of drug combinations in human and veterinary medicine. Recently, it gained new interest for use in long-term pain therapy administered in sub-anesthetic doses in humans and animals. The purpose of this study was to develop a physiologically based pharmacokinetic (PBPk) model for ketamine in ponies and to investigate the effect of low-dose ketamine infusion on the amplitude and the duration of the nociceptive withdrawal reflex (NWR). A target-controlled infusion (TCI) of ketamine with a target plasma level of 1 {mu}g/ml S-ketamine over 120 min under isoflurane anesthesia was performed in Shetland ponies. A quantitative electromyographic assessment of the NWR was done before, during and after the TCI. Plasma levels of R-/S-ketamine and R-/S-norketamine were determined by enantioselective capillary electrophoresis. These data and two additional data sets from bolus studies were used to build a PBPk model for ketamine in ponies. The peak-to-peak amplitude and the duration of the NWR decreased significantly during TCI and returned slowly toward baseline values after the end of TCI. The PBPk model provides reliable prediction of plasma and tissue levels of R- and S-ketamine and R- and S-norketamine. Furthermore, biotransformation of ketamine takes place in the liver and in the lung via first-pass metabolism. Plasma concentrations of S-norketamine were higher compared to R-norketamine during TCI at all time points. Analysis of the data suggested identical biotransformation rates from the parent compounds to the principle metabolites (R- and S-norketamine) but different downstream metabolism to further metabolites. The PBPk model can provide predictions of R- and S-ketamine and norketamine concentrations in other clinical settings (e.g. horses)

  17. The secretion of prolactin (PRL) from pituitary lactotrophs of the rat is predominantly under inhibitory control exerted by

    E-Print Network [OSTI]

    Bertram, Richard

    The secretion of prolactin (PRL) from pituitary lactotrophs of the rat is predominantly under inhibitory control exerted by dopamine (DA) of hypothalamic origin (1). Other PRL-inhibit- ing substances from the Stojilkovic lab (3) and of this report. In addition to the PRL-inhibiting substances, a host

  18. Learning Multiple Models of Non-Linear Dynamics for Control under Varying Contexts 

    E-Print Network [OSTI]

    Petkos, Georgios; Toussaint, Marc; Vijayakumar, Sethu

    For stationary systems, efficient techniques for adaptive motor control exist which learn the system’s inverse dynamics online and use this single model for control. However, in realistic domains the system dynamics often ...

  19. Lateral control of articulated vehicles for automated highway systems under uncertainty in vehicle parameters

    E-Print Network [OSTI]

    Daud, Omar

    1998-01-01T23:59:59.000Z

    Studied in this thesis is the formulation of lateral control algorithms for articulated vehicles performing a lane following maneuver on Automated Highway Systems (AHS). A steering control algorithm using the input/output linearization scheme...

  20. Optimal Waterflood Management under Geologic Uncertainty Using Rate Control: Theory and Field Applications

    E-Print Network [OSTI]

    Alhuthali, Ahmed Humaid H.

    2010-01-16T23:59:59.000Z

    Waterflood optimization via rate control is receiving increased interest because of rapid developments in the smart well completions and I-field technology. The use of inflow control valves (ICV) allows us to optimize the production/injection rates...

  1. The biology and control of the hickory shuckworm Laspeyresia caryana (Fitch) in Texas

    E-Print Network [OSTI]

    Welch, Jimmy Joe

    1968-01-01T23:59:59.000Z

    ) (????ev?b -=) (i Je:. 3. ?e - ) An' n s ???J ?C R The Bioloay and Control of the Hickory Shuckwn -m, Laspeyresia caryana (Fitch), in Texas. (August 1968) Jimmy J. Welch, B. S. , Texas A6?) University Directed by: Dr. P. L. Adkisson ABSTBACT... members of the author's committee: Dr. p. L. Adkisson, Dr. R, L. Hanna, Dr. G. N. Krise, and Mr. N. N. Randolph for their suggestions in planning the grad- uate program and constructive criticism cn this manuscript. Special thanks are extended to Nr...

  2. Robust control under weakened real-time constraints Patrick Jocelyn Andrianiaina, Alexandre Seuret and Daniel Simon

    E-Print Network [OSTI]

    Boyer, Edmond

    of concerns between control design and implementation, [1], [2]. On one hand, traditional control design) is precisely known. This assumption has served the separation between control and scheduling designs, but leads real-time systems design methods and associated analysis tools do not provide a model flexible enough

  3. Steady-state bumpless transfer under controller uncertainty using the state/output feedback topology

    SciTech Connect (OSTI)

    Zheng, K.; Lee, A.H.; Bentsman, J.; Taft, C.W. [University of Illinois, Urbana, IL (United States)

    2006-01-15T23:59:59.000Z

    Linear quadratic (LQ) bumpless transfer design introduced recently by Turner and Walker gives a very convenient and straightforward computational procedure for the steady-state bumpless transfer operator synthesis. It is, however, found to be incapable of providing convergence of the output of the offline controller to that of the online controller in several industrial applications, producing bumps in the plant output in the wake of controller transfer. An examination of this phenomenon reveals that the applications in question are characterized by a significant mismatch, further referred to as controller uncertainty, between the dynamics of the implemented controllers and their models used in the transfer operator computation. To address this problem, while retaining the convenience of the Turner and Walker design, a novel state/output feedback bumpless transfer topology is introduced that employs the nominal state of the offline controller and, through the use of an additional controller/model mismatch compensator, also the offline controller output. A corresponding steady-state bumpless transfer design procedure along with the supporting theory is developed for a large class of systems. Due to these features, it is demonstrated to solve a long-standing problem of high-quality steady-state bumpless transfer from the industry standard low-order nonlinear multiloop PID-based controllers to the modern multiinput-multioutput (MIMO) robust controllers in the megawatt/throttle pressure control of a typical coal-fired boiler/turbine unit.

  4. Optimal Control of Distributed Energy Resources and Demand Response under Uncertainty

    E-Print Network [OSTI]

    Siddiqui, Afzal

    2010-01-01T23:59:59.000Z

    of Distributed Energy Resources and Demand Response underof Distributed Energy Resources and Demand Response underof Distributed Energy Resources and Demand Response under

  5. Self-referencing cellular automata: A model of the evolution of information control in biological systems

    E-Print Network [OSTI]

    Theodore P. Pavlic; Alyssa M. Adams; Paul C. W. Davies; Sara Imari Walker

    2014-05-16T23:59:59.000Z

    Cellular automata have been useful artificial models for exploring how relatively simple rules combined with spatial memory can give rise to complex emergent patterns. Moreover, studying the dynamics of how rules emerge under artificial selection for function has recently become a powerful tool for understanding how evolution can innovate within its genetic rule space. However, conventional cellular automata lack the kind of state feedback that is surely present in natural evolving systems. Each new generation of a population leaves an indelible mark on its environment and thus affects the selective pressures that shape future generations of that population. To model this phenomenon, we have augmented traditional cellular automata with state-dependent feedback. Rather than generating automata executions from an initial condition and a static rule, we introduce mappings which generate iteration rules from the cellular automaton itself. We show that these new automata contain disconnected regions which locally act like conventional automata, thus encapsulating multiple functions into one structure. Consequently, we have provided a new model for processes like cell differentiation. Finally, by studying the size of these regions, we provide additional evidence that the dynamics of self-reference may be critical to understanding the evolution of natural language. In particular, the rules of elementary cellular automata appear to be distributed in the same way as words in the corpus of a natural language.

  6. Sediment studies of the biological factors controlling the reduction of U(VI).

    SciTech Connect (OSTI)

    Lovley, derek, R.

    2004-08-04T23:59:59.000Z

    Studies were conducted primarily with sediments, both in laboratory incubations and in a field experiment, with supporting studies with pure cultures. To our knowledge the sediment studies were the first on microbial U(VI) reduction in actual uranium-contaminated subsurface sediments, under conditions that mimic those found in situ. Important findings included: (1) U(VI) reduction is a biotic process in subsurface sediments. (2) U(VI) reduction can be stimulated most effectively with the addition of acetate. Although it had been speculated that microbial U(VI) reduction might be capable of this type of environmental remediation ever since the discovery of microbial U(VI) reduction, this had not been previously demonstrated under environmentally relevant conditions. (3) U(VI) is reduced concurrently with Fe(III) and prior to sulfate reduction. U(VI) and Fe(III) reduction proceeded concurrently, accompanied by a dramatic enrichment in organisms in the Geobacteraceae. Sulfate-reducing microorganisms do not appear to be important components of the microbial community reducing U(VI) in these subsurface sediments. (4) Nitrate has important influences on U(VI) reduction. Nitrate inhibits the reduction of metals until nitrate is depleted. Fe(III)-reducing microorganisms such as Geobacter metallireducens and Desulfitobacterium species can oxidize Fe(II) with the reduction of nitrate which is an important consideration because our previous studies have demonstrated that freshly precipitated Fe(III) oxides can reoxidize U(IV) to U(VI). The discovery that G. metallireducens can ''run backwards'' and oxidize U(IV) when nitrate is present reveals another mechanism preventing precipitation of U(IV) in the presence of nitrate as well as potential novel strategy for removing uranium from the subsurface after a site has been remediated. (5) Importance of understanding Fe(III) forms available for microbial reduction. Fe(III) is orders of magnitude more abundant than U(VI) as an electron acceptor to support microbial growth. It was demonstrated that poorly crystalline Fe(III) oxides and structural Fe(III) in clays are the predominant forms of microbially reducible Fe(III). Such findings are important for the development of models of Fe(III) reduction in similar aquifer environments, such as those found at many UMTRA sites. (6) Mechanisms for Fe(III) oxide reduction. It was discovered that phylogenetically distinct Fe(III) reducer have different strategies for reducing Fe(III) and the fact that Geobacter species must directly contact Fe(III) in order to reduce it may help explain its predominance over other Fe(III) reducers in the subsurface. (7) Transfer of laboratory results to the field. Results from laboratory studies were used to design a field experiment in which U(VI) reduction was successfully precipitated from the contaminated water with the injection of acetate.

  7. Biological and Environmental Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Focus Area team for Soil Metagenomics and Carbon Cycling develops and uses community genomics approaches to link the biological processes controlling belowground carbon storage...

  8. Absolute vs. Intensity Limits for CO2 Emission Control: Performance Under Uncertainty

    E-Print Network [OSTI]

    Sue Wing, Ian.

    We elucidate the differences between absolute and intensity-based limits of CO2 emission when there is uncertainty about the future. We demonstrate that the two limits are identical under certainty, and rigorously establish ...

  9. Apparatus and method to control atmospheric water vapor composition and concentration during dynamic cooling of biological tissues in conjunction with laser irradiations

    DOE Patents [OSTI]

    Nelson, J. Stuart (Laguna Niguel, CA); Anvari, Bahman (Houston, TX); Tanenbaum, B. Samuel (Irvine, CA); Milner, Thomas E. (Austin, TX)

    1999-01-01T23:59:59.000Z

    Cryogen spray cooling of skin surface with millisecond cryogen spurts is an effective method for establishing a controlled temperature distribution in tissue and protecting the epidermis from nonspecific thermal injury during laser mediated dermatological procedures. Control of humidity level, spraying distance and cryogen boiling point is material to the resulting surface temperature. Decreasing the ambient humidity level results in less ice formation on the skin surface without altering the surface temperature during the cryogen spurt. For a particular delivery nozzle, increasing the spraying distance to 85 millimeters lowers the surface temperature. The methodology comprises establishing a controlled humidity level in the theater of operation of the irradiation site of the biological tissues before and/or during the cryogenic spray cooling of the biological tissue. At cold temperatures calibration was achieved by mounting a thermistor on a thermoelectric cooler. The thermal electric cooler was cooled from from 20.degree. C. to about -20.degree. C. while measuring its infrared emission.

  10. Method for use of hydraulically or electrically controlled solenoids under failed on conditions

    DOE Patents [OSTI]

    Bolenbaugh, Jonathan M.; Naqi, Syed

    2014-07-08T23:59:59.000Z

    A method to operate a clutch device in an electro-mechanical transmission mechanically-operatively coupled to an internal combustion engine and at least one electric machine includes, in response to a failure condition detected within a flow control device configured to facilitate flow of hydraulic fluid for operating the clutch device, selectively preventing the flow of hydraulic fluid from entering the flow control device and feeding the clutch device. Synchronization of the clutch device is initiated when the clutch device is intended for activation, and only if the clutch device is synchronized, the flow of hydraulic fluid is selectively permitted to enter the flow control device to activate the clutch device.

  11. High Performance Repetitive Control of an Active Filter under Varying Network

    E-Print Network [OSTI]

    Hammerton, James

    -Castell´o, Shane Malo, Robert Gri~n´o Institut d'Organitzaci´o i Control de Sistemes Industrials (IOC), Universitat proposed including parallel (shunt active filters), serial and hybrid serial-parallel connections, mixed

  12. Microfluidic devices for studying heterotypic cell-cell interactions and tissue specimen cultures under controlled microenvironments

    E-Print Network [OSTI]

    Zervantonakis, Ioannis K.

    Microfluidic devices allow for precise control of the cellular and noncellular microenvironment at physiologically relevant length- and time-scales. These devices have been shown to mimic the complex in vivo microenvironment ...

  13. Minimum State Awareness for Resilient Control Systems Under Cyber-Attack

    SciTech Connect (OSTI)

    Kisner, Roger [ORNL; Fugate, David L [ORNL; McIntyre, Timothy J [ORNL

    2012-01-01T23:59:59.000Z

    State awareness for a control system is the accurate knowledge of the internal states of the system realization. To maintain stable operation, a controller requires a certain degree of state awareness. By definition, a cyber-attacker decreases the state awareness by modifying or removing the information available to the operator and control system. By doing so, the attacker can directly cause damage to the physical system through the control system, or indirectly by causing the operator to react in a damaging manner to the false information. In a number of recent papers, detection and mitigation strategies have been proposed that assume state awareness. The goal of the attacker to reduce or remove state awareness makes this assumption invalid for most situations. One of the central problems of resilient control is developing methods to retain sufficient state awareness to continue operation during a cyberattack. In this paper, we will define state awareness, discuss the consequences of loss of state awareness, and some potential research directions for maintaining state awareness.

  14. Biological Control of Saltcedar

    E-Print Network [OSTI]

    Knutson, Allen E.; DeLoach, C. Jack; Muegge, Mark A.

    2003-10-21T23:59:59.000Z

    Saltcedar is an exotic shrub or small tree that has spread throughout the rivers, streams and lakes of west and southwest Texas and other areas of the western United States. This brochure explains an effort to introduce the saltcedar leaf beetle...

  15. Design and implementation of a universal controller working under the MCX-16 real-time kernel

    E-Print Network [OSTI]

    Xue, Yuannong

    1995-01-01T23:59:59.000Z

    Cenunl Kelp'aue 10 3 DA0832 2- LF351 3 4 I 5 256K 2- LF351 3 4 I 5 I OK I OK LF35 I + I 5 nut 4 6 -IOV 6 -IOV 6 -I OV Figure 11 Level shift circuit 2. Gain control amplifier Again, the programmable amplifier in Figure 10 is used...

  16. Contraction Control of a Fleet Circular Formation of AUVs under Limited Communication Range

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    including cooperative control of underwater and unmanned air vehicles (AUVs and UAVs) [3], [4], consensus [1 at http://www.lag.ensieg.inpg.fr/connect/ In the context of the source seeking for underwater vehi- cles be more adequate to produce efficient search motions. Another difficulty in the underwater fleet formation

  17. ACTIVE VIBRATION CONTROL OF A DOUBLY-CURVED PANEL UNDER PRESSURISATION

    E-Print Network [OSTI]

    Sóbester, András

    in the aircraft, naval and automotive industries. From a structural dynamics point of view, shells tend of the cabin for the vibrations generated by the engine, turbulent airflow and/or road-tyre interactions. With the rising demand for quieter, lighter and more fuel efficient vehicles, active structural control may

  18. Risk-Sensitive Control Under a Markov Modulated Denial-of-Service Attack Model

    E-Print Network [OSTI]

    Gupta, Vijay

    attacks against critical infrastructure such as power grids and industrial control systems (e.g., see, increasing effort has been placed in addressing the problem of risk and vulnerability assessment to malicious design. As these critical infrastructures become more interconnected and complex, solutions that ensure

  19. Modeling and Control of Aggregated Air Conditioning Loads Under Realistic Conditions

    E-Print Network [OSTI]

    Zhang, Wei

    heaters are examples of TCLs. They use local hysteresis control to maintain either air or water units and water heaters is developed in [7] using detailed physical models. In all the aforementioned for a large fraction of electric demand. HVAC (Heating, Ventilation and air conditioning) systems and water

  20. Control of the local devitrification on oxyfluoride glass doped with Er{sup 3+} ions under diode laser irradiation

    SciTech Connect (OSTI)

    Gonzalez-Perez, S.; Martin, I. R. [Departamento de Fisica Fundamental y Experimental, Electronica y Sistemas, Universidad de La Laguna, 38206 La Laguna, Tenerife (Spain); MALTA Consolider Team, Universidad de La Laguna, 38206 La Laguna, Tenerife (Spain); Jaque, D. [Departamento de Fisica de Materiales, Universidad Autonoma de Madrid, 28049 Madrid (Spain); Haro-Gonzalez, P. [Departamento de Fisica Fundamental y Experimental, Electronica y Sistemas, Universidad de La Laguna, 38206 La Laguna, Tenerife (Spain); Capuj, N. [Departamento de Fisica Basica, Universidad de La Laguna, 38206 La Laguna, Tenerife (Spain)

    2010-11-15T23:59:59.000Z

    Temperature control of the devitrification process in an erbium doped oxyfluoride glass under laser irradiation is reported. The green upconversion emissions around 525 and 545 nm originated from the thermalized {sup 2}H{sub 11/2} and {sup 4}S{sub 3/2} levels were studied when the glass structure changes to glass ceramic during irradiation with a laser beam. Power dependence of the fluorescence intensity ratio was used to determine the temperature of the irradiated zone. The transition from glass to glass ceramic takes place under 2300 mW of laser power with an estimated temperature around 783 K. This result agrees with the one obtained in the samples devitrified under conventional furnace treatment. Therefore, the estimation of the temperature of the irradiated zone through the fluorescence intensity ratio method allows a controlled devitrification. Moreover, an irradiated line has been written in the glass showing an important diffusion of the Pb{sup 2+} and F{sup -} ions. These results confirm that nanocrystals have been created due to the laser action.

  1. EA-2011: Proposed Release of Three Parasitoids for the Biological Control of the Emerald Ash Borer (Agrilus Planipennis) in the Continental United States

    Broader source: Energy.gov [DOE]

    USDA Animal and Plant Health Inspection Service issued an EA (July 2007) that analyzed the potential environmental impacts of the release of three parasitoids into the continental U.S. for the biological control of the emerald ash borer, a nonnative invasive beetle. The DOE Oak Ridge Office reviewed the EA, adopted it, and issued a FONSI for the proposed release of the same parasitoids into the environment on the Oak Ridge Reservation.

  2. Market behavior under partial price controls: the case of the retail gasoline market

    SciTech Connect (OSTI)

    Camm, F.

    1983-03-01T23:59:59.000Z

    The use of firm-specific controls on the price of gasoline during 1979 and 1980, at both the wholesale and the retail level, dramatically affected the retail market for gasoline. The most visible effect was a diversity of monetary prices across service stations within particular retail market areas. Price could no longer play its usual role in clearing the retail market for gasoline. Queues and other changes in quality of service at stations arose to maintain the balance of market demand and supply. This report examines the behavior of an otherwise competitive market in the presence of such regulation-induced nonprice phenomena. In such a market, consumers consider both monetary prices and costs imposed by queues in deciding where to buy gasoline and how much to buy. Using a price-theoretic model of behavior, this paper predicts how various changes in effective price regulation affect consumers. 14 references, 7 figures, 2 tables.

  3. Concepts and Tests for the Remote-Controlled Dismantling of the Biological Shield and Form work of the KNK Reactor - 13425

    SciTech Connect (OSTI)

    Neff, Sylvia; Graf, Anja; Petrick, Holger; Rothschmitt, Stefan [WAK Rueckbau- und Entsorgungs- GmbH, P.O.Box 12 63, 76339 Eggenstein- Leopoldshafen (Germany)] [WAK Rueckbau- und Entsorgungs- GmbH, P.O.Box 12 63, 76339 Eggenstein- Leopoldshafen (Germany); Klute, Stefan [Siempelkamp Nukleartechnik GmbH, Am Taubenfeld 25/1, 69123 Heidelberg (Germany)] [Siempelkamp Nukleartechnik GmbH, Am Taubenfeld 25/1, 69123 Heidelberg (Germany); Stanke, Dieter [Siempelkamp NIS Ingenieurgesellschaft mbH, Industriestrasse 13, 63755 Alzenau (Germany)] [Siempelkamp NIS Ingenieurgesellschaft mbH, Industriestrasse 13, 63755 Alzenau (Germany)

    2013-07-01T23:59:59.000Z

    The compact sodium-cooled nuclear reactor facility Karlsruhe (KNK), a prototype Fast Breeder, is currently in an advanced stage of dismantling. Complete dismantling is based on 10 partial licensing steps. In the frame of the 9. decommissioning permit, which is currently ongoing, the dismantling of the biological shield is foreseen. The biological shield consists of heavy reinforced concrete with built-in steel fitments, such as form-work of the reactor tank, pipe sleeves, ventilation channels, and measuring devices. Due to the activation of the inner part of the biological shield, dismantling has to be done remote-controlled. During a comprehensive basic design phase a practical dismantling strategy was developed. Necessary equipment and tools were defined. Preliminary tests revealed that hot wire plasma cutting is the most favorable cutting technology due to the geometrical boundary conditions, the varying distance between cutter and material, and the heavy concrete behind the steel form-work. The cutting devices will be operated remotely via a carrier system with an industrial manipulator. The carrier system has expandable claws to adjust to the varying diameter of the reactor shaft during dismantling progress. For design approval of this prototype development, interaction between manipulator and hot wire plasma cutting was tested in a real configuration. For the demolition of the concrete structure, an excavator with appropriate tools, such as a hydraulic hammer, was selected. Other mechanical cutting devices, such as a grinder or rope saw, were eliminated because of concrete containing steel spheres added to increase the shielding factor of the heavy concrete. Dismantling of the biological shield will be done in a ring-wise manner due to static reasons. During the demolition process, the excavator is positioned on its tripod in three concrete recesses made prior to the dismantling of the separate concrete rings. The excavator and the manipulator carrier system will be operated alternately. Main boundary condition for all the newly designed equipment is the decommissioning housing of limited space within the reactor building containment. To allow for a continuous removal of the concrete rubble, an additional opening on the lowest level of the reactor shaft will be made. All equipment and the interaction of the tools have to be tested before use in the controlled area. Therefore a full-scale model of the biological shield will be provided in a mock-up. The tests will be performed in early 2014. The dismantling of the biological shield is scheduled for 2015. (authors)

  4. Transurethral ultrasound applicators with dynamic multi-sector control for prostate thermal therapy: In vivo evaluation under MR guidance

    SciTech Connect (OSTI)

    Kinsey, Adam M.; Diederich, Chris J.; Rieke, Viola; Nau, William H.; Pauly, Kim Butts; Bouley, Donna; Sommer, Graham [Thermal Therapy Research Group, Department of Radiation Oncology, University of California, San Francisco, California 94143 (United States) and Joint Graduate Group in Bioengineering, University of California, Berkeley and San Francisco, California 94158 (United States); Department of Radiology, Stanford University Medical Center, Stanford, California 94305 (United States); Thermal Therapy Research Group, Department of Radiation Oncology, University of California, San Francisco, California 94143 (United States); Department of Radiology, Stanford University Medical Center, Stanford, California 94305 (United States); Department of Comparative Medicine, Stanford University, Stanford, California 94305 (United States); Department of Radiology, Stanford University Medical Center, Stanford, California 94305 (United States)

    2008-05-15T23:59:59.000Z

    The purpose of this study was to explore the feasibility and performance of a multi-sectored tubular array transurethral ultrasound applicator for prostate thermal therapy, with potential to provide dynamic angular and length control of heating under MR guidance without mechanical movement of the applicator. Test configurations were fabricated, incorporating a linear array of two multi-sectored tubular transducers (7.8-8.4 MHz, 3 mm OD, 6 mm length), with three 120 deg. independent active sectors per tube. A flexible delivery catheter facilitated water cooling (100 ml min{sup -1}) within an expandable urethral balloon (35 mm longx10 mm diameter). An integrated positioning hub allows for rotating and translating the transducer assembly within the urethral balloon for final targeting prior to therapy delivery. Rotational beam plots indicate {approx}90 deg. - 100 deg. acoustic output patterns from each 120 deg. transducer sector, negligible coupling between sectors, and acoustic efficiencies between 41% and 53%. Experiments were performed within in vivo canine prostate (n=3), with real-time MR temperature monitoring in either the axial or coronal planes to facilitate control of the heating profiles and provide thermal dosimetry for performance assessment. Gross inspection of serial sections of treated prostate, exposed to TTC (triphenyl tetrazolium chloride) tissue viability stain, allowed for direct assessment of the extent of thermal coagulation. These devices created large contiguous thermal lesions (defined by 52 deg. C maximum temperature, t{sub 43}=240 min thermal dose contours, and TTC tissue sections) that extended radially from the applicator toward the border of the prostate ({approx}15 mm) during a short power application ({approx}8-16 W per active sector, 8-15 min), with {approx}200 deg. or 360 deg. sector coagulation demonstrated depending upon the activation scheme. Analysis of transient temperature profiles indicated progression of lethal temperature and thermal dose contours initially centered on each sector that coalesced within {approx}5 min to produce uniform and contiguous zones of thermal destruction between sectors, with smooth outer boundaries and continued radial propagation in time. The dimension of the coagulation zone along the applicator was well-defined by positioning and active array length. Although not as precise as rotating planar and curvilinear devices currently under development for MR-guided procedures, advantages of these multi-sectored transurethral applicators include a flexible delivery catheter and that mechanical manipulation of the device using rotational motors is not required during therapy. This multi-sectored tubular array transurethral ultrasound technology has demonstrated potential for relatively fast and reasonably conformal targeting of prostate volumes suitable for the minimally invasive treatment of BPH and cancer under MR guidance, with further development warranted.

  5. Development and evaluation of a lignite-stillage carrier system for application and study of biological control agents 

    E-Print Network [OSTI]

    Jones, Richard Worth

    1983-01-01T23:59:59.000Z

    Approved as to style and content by: (Chairman of Committee) (Member) (Member) (Head of Department) December 1983 ABSTRACT Development and Evaluation of a Lignite-Sti liege Carrier System for Application and Study of Biological Agents. (December 1983.... The carrier system consisted of lignite granules amended with thin liquid sti llage. This carrier system supported fungal propagule production as high as 2. 0 x 10g propagules/g carrier. Thin liquid sti llage supported the production of 4. 0-4. 5 mg of g...

  6. 2372 IEEE TRANSACTIONS ON AUTOMATIC CONTROL, VOL. 58, NO. 9, SEPTEMBER 2013 Observability of a Linear System Under

    E-Print Network [OSTI]

    Yüksel, Serdar

    notion of controllability, these form the essence of modern linear control theory. In this technical note states intact. Furthermore, with the increasing emphasis on networked control systems, it has been realized that the controllability and observability concepts for linear systems with controllers having

  7. AGRI-SCIENCE CHEMICAL BIOLOGY

    E-Print Network [OSTI]

    photosynthetic efficiency Improve chemical agronomic and agro-ecological control measures Modelling through translation of chemical biology tools and technologies Control weeds, disease and pests Minimise a platform to steer future research and policy directions. · Encourage external outreach to engage

  8. Oxygen Modulation via Microfluidic Devices Oxygen is a key but under-studied metabolic variable. It influences biological phenomena as diverse as

    E-Print Network [OSTI]

    Ben-Arie, Jezekiel

    Oxygen Modulation via Microfluidic Devices Oxygen is a key but under-studied metabolic variable methods to modulate oxygen are crude and inefficient. Our lab has developed a suite of devices which can rapidly alter oxygen conditions surrounding cells in both position and time.[1-3]. Moreover, because

  9. Classical biological control of Mediterranean fruit fly, Ceratitis capitata (Wiedemann), (Diptera:Tephritidae): natural enemy exploration and nontarget testing 

    E-Print Network [OSTI]

    Trostle Duke, Marcia Katherine

    2006-08-16T23:59:59.000Z

    (Wiedemann) is endemic to tropical, sub-Saharan Africa (Gasparich et al., 1997), and can complete development in the fruiting bodies of over 400 plant species in tropical, subtropical and temperate regions (Copeland et al., 2002; Liquido et al., 1998...). Thus, medfly is one of the most widespread and serious pests of edible fruit (Weems, 1981; Liquido et al., 1990, 1991; White and Elson-Harris, 1992). Damage to fruit initiates when a female oviposits under the fruit?s outer skin. Eggs hatch one...

  10. Control of biologically active degradation zones by vertical heterogeneity: Applications in fractured media. 1997 annual progress report

    SciTech Connect (OSTI)

    Colwell, F.S.; Smith, R.W.; McKinley, J.; Fredrickson, J.; Onstott, T.C.; Reysenbach, A.L.

    1997-11-01T23:59:59.000Z

    'The objective of this research is to determine the relationship between of biologically active contaminant degradation zones in a fractured, subsurface medium and vertical geological heterogeneities. The research is being performed on samples collected from the Test Area North (TAN) site at the Idaho National Engineering and Environmental Laboratory (INEEL) where a dissolved trichloroethylene (TCE) plume is migrating in the basalts and interbed sediments of the Eastern Snake River Plain (ESRP) aquifer. Research results are leading to an enhanced understanding of the constraints that the geochemical and hydrological environment place on the activities and distribution of TCE-degrading organisms in this fractured subsurface medium. Enhanced understanding allows better decisions to be made regarding the use of remedial technologies such as natural attenuation and in situ bioremediation at geologically complex waste sites. Through this research, investigations conducted by the Subsurface Science Program (SSP) at TAN are being extended in order to develop a mechanistic understanding of the coupled geomicrobial and hydrogeochemical processes that are necessary to predict the field-scale intrinsic degradation rates of TCE. The research objective is being accomplished by characterizing paired cores and water samples from boreholes located in differing geochemical and flow environments within the plume. Analysis of these samples will allow the determination of the spatial correlation and microbial characterization. The results presented in this report consist primarily of TAN-33 data as many of those analyses have been completed. Nearly all of the TAN-37 data has yet to be acquired. It should be noted that most of the cores were collected from zones that consist of relatively competent, massive basalt. This was because the authors were doubtful about the quality of samples obtained from rubble zones due to potential alteration by the drilling fluids. Thus, microbiological results on the core samples likely represent a conservative estimate of the types, activities and numbers of the microorganisms present in the borehole.'

  11. Report on the research conducted under the funding of the Sloan foundation postdoctoral fellowship in Computational Molecular Biology [Systematic study of protein-protein complexes] Final report

    SciTech Connect (OSTI)

    Sheinerman, Felix

    2001-06-01T23:59:59.000Z

    A central question in molecular biology is what structural features are common at protein-protein interfaces and what energetic factors define the affinity and specificity of protein-protein association. Analysis of structural and mutational data on protein-protein interfaces revealed that protein-protein interfaces of different functional classes contain many more energetically important charged and polar residues than was previously thought. Since, in the context of protein folding studies, polar interactions are believed to destabilize the folded proteins, this observation raised the question as to the forces that determine the stability of protein complexes. To investigate this issue in detail, the authors developed a number of partitioning schemes that allowed them to investigate the role of selected residues, ion pairs, and networks of polar interactions in protein-protein association. The methods developed were applied to the analysis of four different protein-protein interfaces: the ribonuclease barnase and its inhibitor barstar, the human growth hormone and its receptor, subtype N9 influenze virus neuraminidase and NC41 antibody, and the Ras Binding Domain of kinase cRaf and a Ras homologue Rap1A. The calculations revealed a surprising variability in how polar interactions affect the stability of different complexes. The finding that positions of charged and polar residues on protein-protein interfaces are optimized with respect to electrostatic interactions suggests that this property can be employed for the discrimination between native conformations and trial complexes generated by a docking algorithm. Analysis indicated the presence of SH2 domains in Janus family of non-receptor protein tyrosine kinases.

  12. Investigation of Dynamic Aerodynamics and Control of Wind Turbine Sections Under Relevant Inflow/Blade Attitude Conditions

    SciTech Connect (OSTI)

    Naughton, Jonathan W. [University of Wyoming

    2014-08-05T23:59:59.000Z

    The growth of wind turbines has led to highly variable loading on the blades. Coupled with the relative reduced stiffness of longer blades, the need to control loading on the blades has become important. One method of controlling loads and maximizing energy extraction is local control of the flow on the wind turbine blades. The goal of the present work was to better understand the sources of the unsteady loading and then to control them. This is accomplished through an experimental effort to characterize the unsteadiness and the effect of a Gurney flap on the flow, as well as an analytical effort to develop control approaches. It was planned to combine these two efforts to demonstrate control of a wind tunnel test model, but that final piece still remains to be accomplished.

  13. A test platform for measuring the energy efficiency of AC induction motors under various loading conditions and control schemes/

    E-Print Network [OSTI]

    Granata, John A. (John Anthony)

    2012-01-01T23:59:59.000Z

    A test platform was developed to measure and compare the energy efficiency of an AC induction motor under steady-state and cyclical loading conditions while operating in both a constant speed mode and while performing speed ...

  14. MS.BIOLOGY.THESIS ACADEMIC LEARNING PLAN

    E-Print Network [OSTI]

    O'Laughlin, Jay

    effectively to constructive feedback. Job Prospects for Biology Graduates MS in Biology Bioremediation Biotechnology Medical Research Industry Government Education Microbiology Health Professions Research Health Food Production Pollution Control Environmental Diagnostics Forestry Agriculture #12;APPENDIX B

  15. Experimental investigation of piston heat transfer under conventional diesel and reactivity-controlled compression ignition combustion regimes

    SciTech Connect (OSTI)

    Splitter, Derek A [ORNL; Hendricks, Terry Lee [Sandia National Laboratories (SNL); Ghandhi, Jaal B [University of Wisconsin

    2014-01-01T23:59:59.000Z

    The piston of a heavy-duty single-cylinder research engine was instrumented with 11 fast-response surface thermocouples, and a commercial wireless telemetry system was used to transmit the signals from the moving piston. The raw thermocouple data were processed using an inverse heat conduction method that included Tikhonov regularization to recover transient heat flux. By applying symmetry, the data were compiled to provide time-resolved spatial maps of the piston heat flux and surface temperature. A detailed comparison was made between conventional diesel combustion and reactivity-controlled compression ignition combustion operations at matched conditions of load, speed, boost pressure, and combustion phasing. The integrated piston heat transfer was found to be 24% lower, and the mean surface temperature was 25 C lower for reactivity-controlled compression ignition operation as compared to conventional diesel combustion, in spite of the higher peak heat release rate. Lower integrated piston heat transfer for reactivity-controlled compression ignition was found over all the operating conditions tested. The results showed that increasing speed decreased the integrated heat transfer for conventional diesel combustion and reactivity-controlled compression ignition. The effect of the start of injection timing was found to strongly influence conventional diesel combustion heat flux, but had a negligible effect on reactivity-controlled compression ignition heat flux, even in the limit of near top dead center high-reactivity fuel injection timings. These results suggest that the role of the high-reactivity fuel injection does not significantly affect the thermal environment even though it is important for controlling the ignition timing and heat release rate shape. The integrated heat transfer and the dynamic surface heat flux were found to be insensitive to changes in boost pressure for both conventional diesel combustion and reactivity-controlled compression ignition. However, for reactivity-controlled compression ignition, the mean surface temperature increased with changes in boost suggesting that equivalence ratio affects steady-state heat transfer.

  16. Biological Safety

    Broader source: Energy.gov [DOE]

    The DOE's Biological Safety Program provides a forum for the exchange of best practices, lessons learned, and guidance in the area of biological safety. This content is supported by the Biosurety Executive Team. The Biosurety Executive Team is a DOE-chartered group. The DOE Office of Worker Safety and Health Policy provides administrative support for this group. The group identifies biological safety-related issues of concern to the DOE and pursues solutions to issues identified.

  17. BIOLOGICAL CONTROL Classical Biological Control of the Australian Weevil Gonipterus

    E-Print Network [OSTI]

    Hanks, Lawrence M.

    (Coleoptera: Curculionidae) in California L. M. HANKS, J. G. MILLAR,1 T. D. PAINE,1 AND C. D. CAMPBELL1 deposit hard brown egg capsules on shoots and the youngest leaves, and may produce 20Ð30 capsules, each

  18. Biological Control of Music Systems

    E-Print Network [OSTI]

    Miranda, Eduardo Reck

    ? Sonification for Auditory Display Some sort of compositional system Tenney's Meta-Hodos is current source Rock-Music #12;Music for Solo Performer Performed November 14, 1999 Used "Automates Ki" system February 2006 in TheUpgrade! Human multi-band EEG 8-channel sound reproduction Hybrid physical/source

  19. Control Optimization for a Chilled Water Thermal Storage System Under a Complicated Time-of-Use Electricity Rate Schedule

    E-Print Network [OSTI]

    Zhou, J.; Wei, G.; Turner, W.D.; Deng, S.; Claridge, D.E.; Contreras, O.

    processes. A chiller start-stop optimization program was developed and implemented into the Energy Management and Control System (EMCS) to determine the number of chillers that need to be brought on line and the start and stop times for each chiller... every day, based on the prediction of the campus cooling load within the next 24 hours. With timely and accurate weather forecasting, the actual tank charging and discharging process closely matches the simulated process. The chiller plant...

  20. A new control strategy to improve the performance of PWM ac to dc converter under unbalanced operating condition

    E-Print Network [OSTI]

    Choudhury, Shamim A.

    1992-01-01T23:59:59.000Z

    , this improved performance of the converter is not necessarily achieved. Unbalanced voltage inputs introduce a significant amount of unwanted harmonics in the input current and output voltage of the converter. These unwanted harmonics result in increased... and to develop some techniques to preserve their high performance features. This thesis. therefore. presents a new control strategy which selectively cancels the generated abnormal harmonics from the input and output waveforms without the addition of any...

  1. Systems Biology. | EMSL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biology. Systems Biology. Abstract: The biology revolution over the last 50 years has been driven by the ascendancy of molecular biology. This was enthusiastically embraced by most...

  2. Impact evaluation of a refrigeration control system installed at Vitamilk Dairy, Incorporated under the Energy $avings Plan

    SciTech Connect (OSTI)

    Brown, D.R.; Dixon, D.R.; Spanner, G.E.

    1995-01-01T23:59:59.000Z

    This impact evaluation of a refrigeration control system (RCS) recently installed at Vitamilk Dairy, Inc. (Vitamilk) was conducted for the Bonneville Power Administration (Bonneville) as part of an evaluation of its Energy $avings Plan (E$P) Program. The RCS installation at Vitamilk uses microcomputer- based controls to automate refrigeration equipment previously controlled manually. This impact evaluation assessed how much electricity is being saved at Vitamilk as a result of the E$P and to determine how much the savings cost Bonneville and the region. On a unit savings basis, this project will save 9.7 kWh/tonne (8-8 kWh/ton) of milk and ice cream produced, based on the product mix for June 1992 through May 1993, representing a 28% reduction in energy consumption. The project was installed in 1992 for a total cost of $129,330, and Vitamilk received payment of $62,974 from Bonneville in 1993 for the acquisition of energy savings. The real levelized cost of these energy savings to Bonneville is 8.5 mills/kWh (in 1993 dollars) over the project`s assumed 15-year life, and the real levelized cost to the region is 17.9 mills/kWh (in 1993 dollars), not including transmission and distribution effects. Based on the expected project installation costs and energy savings benefits, the RCS would not have been implemented by Vitamilk without the E$P acquisition payment. The expected acquisition payment reduced the estimated payback period from 7.0 to 2.8 years. Although Vitamilk would generally require an energy conservation project to have a payback period of two years or less, the slightly longer payback period was accepted in this case.

  3. Cloning and characterization of EXC-1, an IRGP homologue that controls Intracellular Trafficking and the Maintenance of Shape in Small Biological Tubes

    E-Print Network [OSTI]

    Grussendorf, Kelly Ann

    2013-08-31T23:59:59.000Z

    Biological tubes are ubiquitous structures that carry out vital roles. The formation and maintenance of these tubule structures is a fundamental process in most organisms. The goal of this work is to get a better understanding ...

  4. Biological preconcentrator

    DOE Patents [OSTI]

    Manginell, Ronald P. (Albuquerque, NM); Bunker, Bruce C. (Albuquerque, NM); Huber, Dale L. (Albuquerque, NM)

    2008-09-09T23:59:59.000Z

    A biological preconcentrator comprises a stimulus-responsive active film on a stimulus-producing microfabricated platform. The active film can comprise a thermally switchable polymer film that can be used to selectively absorb and desorb proteins from a protein mixture. The biological microfabricated platform can comprise a thin membrane suspended on a substrate with an integral resistive heater and/or thermoelectric cooler for thermal switching of the active polymer film disposed on the membrane. The active polymer film can comprise hydrogel-like polymers, such as poly(ethylene oxide) or poly(n-isopropylacrylamide), that are tethered to the membrane. The biological preconcentrator can be fabricated with semiconductor materials and technologies.

  5. 2013 IREP Symposium-Bulk Power System Dynamics and Control -IX (IREP), August 25-30, 2013, Rethymnon, Greece A Probabilistic Approach to Power System Security Assessment under Uncertainty

    E-Print Network [OSTI]

    Gross, George

    2013 IREP Symposium-Bulk Power System Dynamics and Control -IX (IREP), August 25-30, 2013, Rethymnon, Greece A Probabilistic Approach to Power System Security Assessment under Uncertainty D. D. Le, A uncer- tainty into power system operation and control. This added uncertainty, together

  6. Optimal Feedback Control for Anthropomorphic Manipulators Djordje Mitrovic, Sho Nagashima, Stefan Klanke, Takamitsu Matsubara, Sethu Vijayakumar

    E-Print Network [OSTI]

    Vijayakumar, Sethu

    anthropomorphic manipulators under the premise of minimal energy consumption and compliance during motion. We. We highlight the benefits of this biologically plausible motor control strategy over traditional (open loop) optimal controllers: The presented approach proves to be significantly more energy efficient

  7. Biological particle identification apparatus

    DOE Patents [OSTI]

    Salzman, Gary C. (Los Alamos, NM); Gregg, Charles T. (Los Alamos, NM); Grace, W. Kevin (Los Alamos, NM); Hiebert, Richard D. (Los Alamos, NM)

    1989-01-01T23:59:59.000Z

    An apparatus and method for making multiparameter light scattering measurements from suspensions of biological particles is described. Fourteen of the sixteen Mueller matrix elements describing the particles under investigation can be substantially individually determined as a function of scattering angle and probing radiations wavelength, eight elements simultaneously for each of two apparatus configurations using an apparatus which incluees, in its simplest form, two polarization modulators each operating at a chosen frequency, one polarizer, a source of monochromatic electromagnetic radiation, a detector sensitive to the wavelength of radiation employed, eight phase-sensitive detectors, and appropriate electronics. A database of known biological particle suspensions can be assembled, and unknown samples can be quickly identified once measurements are performed on it according to the teachings of the subject invention, and a comparison is made with the database.

  8. Bioinformatics & Computational Biology

    E-Print Network [OSTI]

    Richner, Heinz

    Bioinformatics & Computational Biology Master of Science in Bioinformatics and Computational Biology (90 ECTS) Contact Information Programme administration Bioinformatics and Computational Biology.unifr.ch/msc Programme administration Bioinformatics and Computational Biology University of Bern Baltzerstrasse 6 CH

  9. Probe into Gaseous Pollution and Assessment of Air Quality Benefit under Sector Dependent Emission Control Strategies over Megacities in Yangtze River Delta, China

    SciTech Connect (OSTI)

    Dong, Xinyi; Gao, Yang; Fu, Joshua S.; Li, Juan; Huang, Kan; Zhuang, G.; Zhou, Ying

    2013-11-01T23:59:59.000Z

    On February 29th 2012, China published its new National Ambient Air Quality Standard (CH-NAAQS) aiming at revising the standards and measurements for both gaseous pollutants including ozone (O3), nitrogen dioxide (NO2), and sulfur dioxide (SO2), and also particle pollutants including PM10 and PM2.5. In order to understand the air pollution status regarding this new standard, the integrated MM5/CMAQ modeling system was applied over Yangtze River Delta (YRD) within this study to examine the criteria gaseous pollutants listed in the new CH-NAAQS. Sensitivity simulations were also conducted to assess the responses of gaseous pollutants under 8 different sector-dependent emission reduction scenarios in order to evaluate the potential control strategies. 2006 was selected as the simulation year in order to review the air quality condition at the beginning of China’s 11th Five-Year-Plan (FYP, from 2006 to 2010), and also compared with air quality status in 2010 as the end of 11th FYP to probe into the effectiveness of the national emission control efforts. Base case simulation showed distinct seasonal variation for gaseous pollutants: SO2, and NO2 were found to have higher surface concentrations in winter while O3 was found to have higher concentrations in spring and summer than other seasons. According to the analyses focused on 3 megacities within YRD, Shanghai, Nanjing, and Hangzhou, we found different air quality conditions among the cities: NO2 was the primary pollutant that having the largest number of days exceeding the CH-NAAQS daily standard (80 ?g/m3) in Shanghai (59 days) and Nanjing (27 days); SO2 was the primary pollutant with maximum number of days exceeding daily air quality standard (150 ?g/m3) in Hangzhou (28 days), while O3 exceeding the daily maximum 8-hour standard (160 ?g/m3) for relatively fewer days in all the three cities (9 days in Shanghai, 14 days in Nanjing, and 11 days in Hangzhou). Simulation results from predefined potential applicable emission control scenarios suggested significant air quality improvements from emission reduction: 90% of SO2 emission removed from power plant in YRD would be able to reduce more than 85% of SO2 pollution, 85% NOx emission reduction from power plant would reduce more than 60% of NO2 pollution, in terms of reducing the number of days exceeding daily air quality standard. NOx emission reduction from transportation and industry were also found to effectively reduce NO2 pollution but less efficient than emission control from power plants. We also found that multi-pollutants emission control including both NOx and VOC would be a better strategy than independent NOx control over YRD which is China’s 12th Five-Year-Plan (from 2011 to 2015), because O3 pollution would be increased as a side effect of NOx control and counteract NO2 pollution reduction benefit.

  10. An Introduction to Quantum Control

    E-Print Network [OSTI]

    James, Matthew

    , stochastic control, quantum control, systems biology, networks, etc modern control #12;Quantum Control: Control of physical systems whose behaviour is dominated by the laws of quantum mechanics. 2003: Dowling of Quantum Control: controller quantum system control actions #12;· Closed loop - control actions depend

  11. 2013 IREP Symposium-Bulk Power System Dynamics and Control -IX (IREP), August 25-30, 2013, Rethymnon, Greece Active network management: planning under

    E-Print Network [OSTI]

    Ernst, Damien

    , Rethymnon, Greece Active network management: planning under uncertainty for exploiting load modulation

  12. Biological Statistics and Computational Biology Seminar Series

    E-Print Network [OSTI]

    Keinan, Alon

    . Williams Professor of Biomedical Informations and Co-Director, Yale Computational Biology & Bioinformatics co-director of the Yale Computational Biology and Bioinformatics Program. In addition to the KeckBiological Statistics and Computational Biology Seminar Series Dr. Mark B. Gerstein Albert L

  13. MS.BIOLOGY.NON-THESIS ACADEMIC LEARNING PLAN

    E-Print Network [OSTI]

    O'Laughlin, Jay

    to constructive feedback Job Prospects for Biology Graduates MS/non-thesis in Biology Bioremediation Biotechnology Medical Research Industry Government Education Microbiology Health Professions Research Laboratories Find Food Production Pollution Control Environmental Diagnostics Forestry Agriculture #12;MS

  14. Crack stability in a representative piping system under combined inertial and seismic/dynamic displacement-controlled stresses. Subtask 1.3 final report

    SciTech Connect (OSTI)

    Scott, P.; Olson, R.; Wilkowski, O.G.; Marschall, C.; Schmidt, R.

    1997-06-01T23:59:59.000Z

    This report presents the results from Subtask 1.3 of the International Piping Integrity Research Group (IPIRG) program. The objective of Subtask 1.3 is to develop data to assess analysis methodologies for characterizing the fracture behavior of circumferentially cracked pipe in a representative piping system under combined inertial and displacement-controlled stresses. A unique experimental facility was designed and constructed. The piping system evaluated is an expansion loop with over 30 meters of 16-inch diameter Schedule 100 pipe. The experimental facility is equipped with special hardware to ensure system boundary conditions could be appropriately modeled. The test matrix involved one uncracked and five cracked dynamic pipe-system experiments. The uncracked experiment was conducted to evaluate piping system damping and natural frequency characteristics. The cracked-pipe experiments evaluated the fracture behavior, pipe system response, and stability characteristics of five different materials. All cracked-pipe experiments were conducted at PWR conditions. Material characterization efforts provided tensile and fracture toughness properties of the different pipe materials at various strain rates and temperatures. Results from all pipe-system experiments and material characterization efforts are presented. Results of fracture mechanics analyses, dynamic finite element stress analyses, and stability analyses are presented and compared with experimental results.

  15. Genome Biology 2006, 7:320 commentreviewsreportsdepositedresearchinteractionsinformationrefereedresearch

    E-Print Network [OSTI]

    Pritham, Ellen J.

    Genome Biology 2006, 7:320 commentreviewsreportsdepositedresearchinteractionsinformationrefereedresearch Meeting report Mobile DNA: genomes under the influence Cédric Feschotte and Ellen J Pritham Feschotte. Email: cedric@uta.edu Published: 30 June 2006 Genome Biology 2006, 7:320 (doi:10.1186/gb-2006

  16. Characterisation of the bacterial flora associated with the grey field slug Deroceras reticulatum and assessment of its suitability as a target for biological control 

    E-Print Network [OSTI]

    Wilkinson, Peter Graham

    2011-06-27T23:59:59.000Z

    The field slug Deroceras reticulatum is a major pest in UK agriculture and amidst growing concern and regulatory pressures surrounding chemical molluscicides, innovation is required to advance the current repertoire of slug controls. This study set...

  17. Genomics-Bioinformatics Day: "Bioinformatics, Computational Biology, Systems Biology & Mathematical

    E-Print Network [OSTI]

    Goldschmidt, Christina

    3rd Genomics-Bioinformatics Day: "Bioinformatics, Computational Biology, Systems Biology on "Bioinformatics, Computational Biology, Systems Biology & Mathematical Biology: Their Relationship". Genomics, Bioinformatics, Computational Biology have a tremendous appeal and these fields have originated or grown

  18. ANAEROBIC BIOLOGICAL TREATMENT OF PRODUCED WATER

    SciTech Connect (OSTI)

    John R. Gallagher

    2001-07-31T23:59:59.000Z

    During the production of oil and gas, large amounts of water are brought to the surface and must be disposed of in an environmentally sensitive manner. This is an especially difficult problem in offshore production facilities where space is a major constraint. The chief regulatory criterion for produced water is oil and grease. Most facilities have little trouble meeting this criterion using conventional oil-water separation technologies. However, some operations have significant amounts of naphthenic acids in the water that behave as oil and grease but are not well removed by conventional technologies. Aerobic biological treatment of naphthenic acids in simulated-produced water has been demonstrated by others; however, the system was easily overloaded by the large amounts of low-molecular-weight organic acids often found in produced waters. The objective of this research was to determine the ability of an anaerobic biological system to treat these organic acids in a simulated produced water and to examine the potential for biodegradation of the naphthenic acids in the anaerobic environment. A small fixed-film anaerobic biological reactor was constructed and adapted to treat a simulated produced water. The bioreactor was tubular, with a low-density porous glass packing material. The inocula to the reactor was sediment from a produced-water holding pond from a municipal anaerobic digester and two salt-loving methanogenic bacteria. During start-up, the feed to the reactor contained glucose as well as typical produced-water components. When glucose was used, rapid gas production was observed. However, when glucose was eliminated and the major organic component was acetate, little gas was generated. Methane production from acetate may have been inhibited by the high salt concentrations, by sulfide, or because of the lack, despite seeding, of microbes capable of converting acetate to methane. Toluene, a minor component of the produced water (0.1 g/L) was removed in the reactor. Batch tests were conducted to examine naphthenic acid biodegradability under several conditions. The conditions used were seed from the anaerobic reactor, wetland sediments under aerobic and anaerobic conditions, and a sterile control. The naphthenic acid was from a commercial source isolated from Gulf Coast petroleum as was dosed at 2 mg/mL. The incubations were for 30 days at 30 C. The results showed that the naphthenic acids were not biodegraded under anaerobic conditions, but were degraded under aerobic conditions. Despite poor performance of the anaerobic reactor, it remains likely that anaerobic treatment of acetate, toluene, and, potentially, other produced-water components is feasible.

  19. Systems biology approach to bioremediation

    SciTech Connect (OSTI)

    Chakraborty, R.; Wu, C. H.; Hazen, T. C.

    2012-01-01T23:59:59.000Z

    Bioremediation has historically been approached as a ?black box? in terms of our fundamental understanding. Thus it succeeds and fails, seldom without a complete understanding of why. Systems biology is an integrated research approach to study complex biological systems, by investigating interactions and networks at the molecular, cellular, community, and ecosystem level. The knowledge of these interactions within individual components is fundamental to understanding the dynamics of the ecosystem under investigation. Understanding and modeling functional microbial community structure and stress responses in environments at all levels have tremendous implications for our fundamental understanding of hydrobiogeochemical processes and the potential for making bioremediation breakthroughs and illuminating the ?black box?.

  20. Bioinformatics Computational Biology

    E-Print Network [OSTI]

    Mayfield, John

    Bioinformatics and Computational Biology Interdepartmental Graduate Program GRADUATE STUDENT HANDBOOK FALL 2006 Bioinformatics and Computational Biology Interdepartmental Graduate Program GRADUATE STUDENT HANDBOOK FALL 2006 #12;1 Welcome to the Bioinformatics and Computational Biology (BCB) program

  1. Biological Statistics and Computational Biology Seminar Series

    E-Print Network [OSTI]

    Keinan, Alon

    Science and the Center for Computational Biology and Bioinformatics at Columbia University. Dr. PeBiological Statistics and Computational Biology Seminar Series Dr. Itsik Pe'er Associate Professor of Computer Science Columbia University Itsik Pe'er is an associate professor in the Department of Computer

  2. Dissecting Cell Signaling Using Synthetic Biology: New Methods...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Dissecting Cell Signaling Using Synthetic Biology: New Methods for Engineered Control of Protein Kinases and Phosphatases Event Sponsor: Argonne Leadership Computing Facility...

  3. Microfluidics for quantitative biology

    E-Print Network [OSTI]

    Adler, Micha

    2012-01-01T23:59:59.000Z

    CALIFORNIA, SAN DIEGO Microfluidics for Quantitative BiologyChapter 1: Microfluidics.………………………………………………………..… 1 1.1OF THE DISSERTATION Microfluidics for Quantitative Biology

  4. Genomics and Systems Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Genomics and Systems Biology Genomics and Systems Biology Los Alamos scientists perform research in functional genomics and structural genomics, and applications for such work...

  5. Plant Vascular Biology 2010

    SciTech Connect (OSTI)

    Ding, Biao

    2014-11-17T23:59:59.000Z

    This grant supported the Second International Conference on Plant Vascular Biology (PVB 2010) held July 24-28, 2010 on the campus of Ohio State University, Columbus, Ohio. Biao Ding (Ohio State University; OSU) and David Hannapel (Iowa State University; ISU) served as co-chairs of this conference. Biao Ding served as the local organizer. PVB is defined broadly here to include studies on the biogenesis, structure and function of transport systems in plants, under conditions of normal plant growth and development as well as of plant interactions with pathogens. The transport systems cover broadly the xylem, phloem, plasmodesmata and vascular cell membranes. The PVB concept has emerged in recent years to emphasize the integrative nature of the transport systems and approaches to investigate them.

  6. A modeling and control framework for operating large-scale electric power systems under present and newly evolving competitive industry structures

    E-Print Network [OSTI]

    Ilic, Marija

    1995-01-01T23:59:59.000Z

    This paper introduces a systematic, structure-based modeling framework for analysis and control of electric power systems for processes evolving over the mid-term and long-term time horizons. Much simpler models than the ...

  7. Ground Control | EMSL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Ground Control Ground Control Released: April 22, 2015 EMSL scientists develop new methods to dig deeper into soil organic matter International Year of the Soils Under our feet...

  8. 2003 Synthetic Biology study

    E-Print Network [OSTI]

    Endy, Drew

    2007-08-14T23:59:59.000Z

    Biology is a technology for processing information, materials, and energy. As a technology platform, biological systems provide access to artifacts and processes across a range of scales (e.g., the ribosome is a programmable ...

  9. INT. 1. CONTROL, 1993, VOL. 58, No.2, 337-348 Necessary and sufficient conditions under which an H2 optimal

    E-Print Network [OSTI]

    Benmei, Chen

    optimal control problem has a unique solution BEN M. CHENt and ALl SABERI:!: 1 A set of necessary and Moore 1989, Fleming and Rishel 1975, Geerts 1989, Kailath 1974, Kwakernaak and Sivan 1972, Saberi.00 @ 1993 Taylor & Francis LId #12;338 B. M. Chen and A. Saberi class of singular H roptimization problems

  10. Biological Systems Facilities

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    encompasses the areas of priority pathogen detection, extremophile biology and genomics, biohydrometallurgy, biomass conversion, coal bioprocessing, biodegradation...

  11. Micro/nanofabricated environments for synthetic biology

    SciTech Connect (OSTI)

    Collier, Pat [ORNL; Simpson, Michael L [ORNL

    2011-01-01T23:59:59.000Z

    A better understanding of how confinement, crowding and reduced dimensionality modulate reactivity and reaction dynamics will aid in the rational and systematic discovery of functionality in complex biological systems. Artificial micro- and nanofabricated structures have helped elucidate the effects of nanoscale spatial confinement and segregation on biological behavior, particularly when integrated with microfluidics, through precise control in both space and time of diffusible signals and binding interactions. Examples of nanostructured interfaces for synthetic biology include the development of cell-like compartments for encapsulating biochemical reactions, nanostructured environments for fundamental studies of diffusion, molecular transport and biochemical reaction kinetics, and regulation of biomolecular interactions as functions of micro- and nanofabricated topological constraints.

  12. Process Manual Biological & Agricultural

    E-Print Network [OSTI]

    Boas, Harold P.

    · · · · ·t t ·t ·t t t ·t . ~ t · · Process· Manual Biological & Agricultural Engineering MANUAL FOR THE BIOLOGICAL AND AGRICULTURAL ENGINEERING DEPARTMENT TexasA&MUniversity Article I. NAME The name ofthis organization shall be the Biological and Agricultural Engineering Department (abbreviated

  13. Computational Biology & Bioinformatics

    E-Print Network [OSTI]

    Johnson, Marcia K.

    Computational Biology & Bioinformatics at Yale An Interdepartmental PhD Program and a Track within://www.yale.edu/graduateschool/admissions/apply_online.html 2 #12;Introduction Computational Biology and Bioinformatics (CBB) is a rapidly developing multi experimentation. Computational and theoretical approaches to understanding biological systems provide an essential

  14. Computational Biology & Bioinformatics

    E-Print Network [OSTI]

    Computational Biology & Bioinformatics at Yale An Interdepartmental PhD Program and a Track within://www.yale.edu/graduateschool/admissions/apply_online.html #12;3 Introduction Computational Biology and Bioinformatics (CBB) is a rapidly developing multi experimentation. Computational and theoretical approaches to understanding biological systems provide an essential

  15. Effect of salinity and temperature under controlled conditions on survival, growth and generation time of a mysid from the Gulf of Mexico 

    E-Print Network [OSTI]

    Rhoads, Joane Shirley

    1966-01-01T23:59:59.000Z

    and Florida. Tulane Stu4. Zool. , 12:15-18 ~ Cannon, H. Q. , an4 S. W. Hwnton. 1928 ~ Qn the feeding mechanism of a mysid crustacean, ~Hem ~ms s lamornae. Trans. Roy. Soo. -'"dinburg, ~:219-253. Costlow, John D. , Jr. 196$. Larval development. i ISS hull...EFFECT GF MLIHITY AHD TEHFKBATUBK UNDER CONTBOLLKD CONDITIONS 'H SURVIVAL& GBOMTR AHD QKNKRATIO? TIFIE OF A HYSID FRON THE GULF OP HKAICO A Thesis Joene Shirley Rhesus Submitted to the Qradmate College of the Texss AkH University in parti?1...

  16. Morphology-controlled synthesis of Ti{sup 3+} self-doped yolk–shell structure titanium oxide with superior photocatalytic activity under visible light

    SciTech Connect (OSTI)

    Wang, Shixiong [School of Chemistry Science and Engineering, Yunnan University, No. 2, Green Lake North Road, Kunming 650091, Yunnan (China); Yang, Xiangjun, E-mail: 573134536@qq.com [School of Chemistry Science and Engineering, Yunnan University, No. 2, Green Lake North Road, Kunming 650091, Yunnan (China); Wang, Yapeng; Liu, Lixiang; Guo, Yuanyuan [School of Chemistry Science and Engineering, Yunnan University, No. 2, Green Lake North Road, Kunming 650091, Yunnan (China); Guo, Hong, E-mail: guohongcom@126.com [School of Chemistry Science and Engineering, Yunnan University, No. 2, Green Lake North Road, Kunming 650091, Yunnan (China); School of Chemistry and Chemical Engineering, Qujing Normal University, Qujing 655000, Yunnan (China)

    2014-05-01T23:59:59.000Z

    Ti{sup 3+} self-doped yolk–shell structure titanium oxide nanoparticle aggregates are fabricated through an environmental template-free route and the reduction reaction at low temperature subsequently. After the Ti{sup 3+} doping, the reduced TiO{sub 2} sample exhibits a wide visible-light absorption ranged from 400 nm to 800 nm. The intrinsic hollow core–shell microstructure can make multiple reflections of light within the chamber, and thus results in more efficient use of the light source compared with solid structure. Besides, the large surface area can render the sample with a high activity. Therefore, Ti{sup 3+} self-doped yolk–shell structure titanium oxide exhibits a superior photocatalytic activity under visible light. This strategy is simple, cheap and mass-productive, which may shed light on a new avenue for large scale production of self-doped yolk–shell structural nano functional materials for catalyst, sensors, energy storage and other new applications. - Graphical abstract: A facile generic strategy is employed to prepare Ti{sup 3+} self-doped yolk–shell structure titanium oxide nanoparticle aggregates with the superior photocatalytic activity under visible light. - Highlights: • Yolk–shell TiO{sub 2} mesospheres are synthesized by solvothermal alcoholysis. • Ti{sup 3+} self-doped yolk–shell structure titanium oxide is obtained at low temperature. • It exhibits a remarkable photocatalytic activity.

  17. Nanostructure Control of Biologically Inspired Polymers

    E-Print Network [OSTI]

    Rosales, Adrianne

    2013-01-01T23:59:59.000Z

    E. B. ; Wagener, K. B. Polymer 2008, 49, 2985-2995. Boz,T. ; Matyjaszewski, K. Polymer 2008, 49, 1567-1578. Kim,Flory, P. J. ; Jackson, J. B. Polymer 1963, 4, (2), 221-236.

  18. Nanostructure Control of Biologically Inspired Polymers

    E-Print Network [OSTI]

    Rosales, Adrianne

    2013-01-01T23:59:59.000Z

    HPLC gradient was 5-95% acetonitrile (solvent B was water)HPLC gradient was 5- 95% acetonitrile (solvent B was water)instead of blocky. Using acetonitrile titrations, it was

  19. Biological Air Emissions Control | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't Your Destiny: The FutureCommentsEnergyandapproximately 10 wt%inand Fuel CellsDepartment

  20. Department of Chemical and Biological Engineering Department of Chemical and Biological Engineering

    E-Print Network [OSTI]

    Heller, Barbara

    Dynamics Lab Fuel Cell Lab Fuel Cell Battery Lab Fluidization Lab Gas Processing Lab Interfacial Phenomena: Energy and Sustainability Fuel Cells Fluidization and Gasification Hybrid Systems Biological Engineering Lab Process Control & Optimization Lab Process Modeling, Monitoring and Control Lab Rheology Lab Riser

  1. Soft Selves and Ecological Control 

    E-Print Network [OSTI]

    Clark, Andy

    2006-01-01T23:59:59.000Z

    Advanced biological brains are by nature open-ended opportunistic controllers. Such controllers compute, pretty much on a moment-to-moment basis, what problem-solving resources are readily available and recruit them into temporary problem...

  2. Controlling Nutria Damage

    E-Print Network [OSTI]

    Texas Wildlife Services

    2007-03-13T23:59:59.000Z

    Nutria are large, semi-aquatic rodents resembling beavers or muskrats. They eat desirable vegetation, girdle trees and burrow into banks and dams. The biological, reproductive and behavioral characteristics of nutria are listed, as well as control...

  3. Biological tracer method

    DOE Patents [OSTI]

    Strong-Gunderson, J.M.; Palumbo, A.V.

    1998-09-15T23:59:59.000Z

    The present invention is a biological tracer method for characterizing the movement of a material through a medium, comprising the steps of: introducing a biological tracer comprising a microorganism having ice nucleating activity into a medium; collecting at least one sample of the medium from a point removed from the introduction point; and analyzing the sample for the presence of the biological tracer. The present invention is also a method for using a biological tracer as a label for material identification by introducing a biological tracer having ice nucleating activity into a material, collecting a sample of a portion of the labelled material and analyzing the sample for the presence of the biological tracer. 2 figs.

  4. Biological tracer method

    DOE Patents [OSTI]

    Strong-Gunderson, Janet M. (Ten Mile, TN); Palumbo, Anthony V. (Oak Ridge, TN)

    1998-01-01T23:59:59.000Z

    The present invention is a biological tracer method for characterizing the movement of a material through a medium, comprising the steps of: introducing a biological tracer comprising a microorganism having ice nucleating activity into a medium; collecting at least one sample of the medium from a point removed from the introduction point; and analyzing the sample for the presence of the biological tracer. The present invention is also a method for using a biological tracer as a label for material identification by introducing a biological tracer having ice nucleating activity into a material, collecting a sample of a portion of the labelled material and analyzing the sample for the presence of the biological tracer.

  5. Biological detector and method

    DOE Patents [OSTI]

    Sillerud, Laurel; Alam, Todd M; McDowell, Andrew F

    2014-04-15T23:59:59.000Z

    A biological detector includes a conduit for receiving a fluid containing one or more magnetic nanoparticle-labeled, biological objects to be detected and one or more permanent magnets or electromagnet for establishing a low magnetic field in which the conduit is disposed. A microcoil is disposed proximate the conduit for energization at a frequency that permits detection by NMR spectroscopy of whether the one or more magnetically-labeled biological objects is/are present in the fluid.

  6. Safety and Health Policy and Procedure Manual Biological Safety Manual

    E-Print Network [OSTI]

    Saidak, Filip

    Biological Safety Association (ABSA) best practices as well as all federal, state, and local regulations. IISafety and Health Policy and Procedure Manual Biological Safety Manual Section 280 INDEX I. Policy space suitable for work being conducted · Under the Office of Research Compliance, establish and manage

  7. A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology

    E-Print Network [OSTI]

    Raines, Ronald T.

    Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, infantile CI deficiency. Our results have important implications for under- standing CI function-onset neurodegeneration and is a likely contributor to cancer and type II diabetes (DiMauro and Schon, 2003; Lowell

  8. Genomics and Systems Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Genomics and Systems Biology LANL leads the world in computational finishing of microbial genomes Read caption + In 2013, Los Alamos scientist Richard Sayre and his team...

  9. Roadmap: Environmental and Conservation Biology Conservation Biology Bachelor of Science

    E-Print Network [OSTI]

    Sheridan, Scott

    Roadmap: Environmental and Conservation Biology ­Conservation Biology Bachelor of Science [AS or upper division) 4 #12;Roadmap: Environmental and Conservation Biology ­Conservation Biology Bachelor Summary on page 2 Conservation Biology Concentration Elective 2 See note 3 on page 2 Semester Five: [15

  10. Apparatus for automated testing of biological specimens

    DOE Patents [OSTI]

    Layne, Scott P. (Los Angeles, CA); Beugelsdijk, Tony J. (Los Alamos, NM)

    1999-01-01T23:59:59.000Z

    An apparatus for performing automated testing of infections biological specimens is disclosed. The apparatus comprise a process controller for translating user commands into test instrument suite commands, and a test instrument suite comprising a means to treat the specimen to manifest an observable result, and a detector for measuring the observable result to generate specimen test results.

  11. AGRICULTURAL AND BIOLOGICAL

    E-Print Network [OSTI]

    Gilbert, Matthew

    AGRICULTURAL AND BIOLOGICAL ENGINEERING UNDERGRADUATE PROGRAM Prepare... yourself for a career in integrating life and engineering for systems in agriculture, food, environment, and energy, and to contribute to the world's largest industry. COLLEGE OF ACES COLLEGE OF ENGINEERING #12;AGRICULTURAL AND BIOLOGICAL

  12. Human Embryology & Developmental Biology

    E-Print Network [OSTI]

    Levi, Ran

    Biology is the modern synthesis of biological and medical sciences that looks at how the tissues, and is at the forefront of recent advances in modern medicine. Current research has shown that many of the molecular Web Pages for names). The Head of School of Medical Sciences is always available for advice regarding

  13. Molecular Biology DEGREE PROGRAMME

    E-Print Network [OSTI]

    Levi, Ran

    to the course co-ordinator for that module (See University Catalogue of Courses or SMS World Wide Web Pages in molecular biology have a wide range of career options, including virtually all areas of biology, medicine with mastering statistics, graphics and word processing software packages. General Enquiries The Degree Programme

  14. Decentralized customerlevel under frequency load shedding in...

    Open Energy Info (EERE)

    enables the management of large groups of distributed loads under a single innovative control schemes to use the flexibility of electrical loads for power system purposes....

  15. Frequency Control Performance Measurement and Requirements

    E-Print Network [OSTI]

    Illian, Howard F.

    2011-01-01T23:59:59.000Z

    Governing under the Power System Stability Subcommittee ofModeling under the Power System Stability Subcommittee ofPGFR) under the Power System Stability Controls Subcommittee

  16. A Study on Biological Threats to Texas Freshwater Resources

    E-Print Network [OSTI]

    Neisch, Michael

    2014-01-15T23:59:59.000Z

    . The second experiment sought to determine the effectiveness of triploid grass carp, Ctenopharyngodon idella, as a biological control for two species of invasive macrophytes, which were giant salvinia, Salvinia molesta, and hygrophila, Hygrophila polysperma...

  17. A Biologically Inspired Networking Model for Wireless Sensor Networks 

    E-Print Network [OSTI]

    Charalambous, Charalambos

    2011-02-22T23:59:59.000Z

    in sensor nodes demand energy-aware network control. In this thesis, we propose an energy- efficient topology management model inspired by biological inter-cellular signaling schemes. The model allows sensor nodes to cluster around imminent targets in a...

  18. Selection of bioclimatically representative biological reserve systems under climate change

    E-Print Network [OSTI]

    Pyke, C R; Fischer, Douglas T

    2005-01-01T23:59:59.000Z

    Journal of the American Water Resources Association 39, 771–for bicriterion problems. Water Resources Research 15, 1001–the accumulation of rain water while restricting the in?

  19. Extracting information from biological networks

    E-Print Network [OSTI]

    Chindelevitch, Leonid Alexandrovich

    2010-01-01T23:59:59.000Z

    Systems biology, the study of biological systems in a holistic manner, has been catalyzed by a dramatic improvement in experimental techniques, coupled with a constantly increasing availability of biological data. The ...

  20. Master track Theoretical Biology & Bioinformatics

    E-Print Network [OSTI]

    Utrecht, Universiteit

    their master. Our two MSc courses "Computational Biology" and "Bioinformatics and Evolutionary GenomicsMaster track Theoretical Biology & Bioinformatics Modeling and bioinformatics is an important Biology & Bioinformatics provides courses introducing you to the basic concepts of modeling

  1. Exploring the Possible Use of Information Barriers for future Biological Weapons Verification Regimes

    SciTech Connect (OSTI)

    Luke, S J

    2011-12-20T23:59:59.000Z

    This report describes a path forward for implementing information barriers in a future generic biological arms-control verification regime. Information barriers have become a staple of discussion in the area of arms control verification approaches for nuclear weapons and components. Information barriers when used with a measurement system allow for the determination that an item has sensitive characteristics without releasing any of the sensitive information. Over the last 15 years the United States (with the Russian Federation) has led on the development of information barriers in the area of the verification of nuclear weapons and nuclear components. The work of the US and the Russian Federation has prompted other states (e.g., UK and Norway) to consider the merits of information barriers for possible verification regimes. In the context of a biological weapons control verification regime, the dual-use nature of the biotechnology will require protection of sensitive information while allowing for the verification of treaty commitments. A major question that has arisen is whether - in a biological weapons verification regime - the presence or absence of a weapon pathogen can be determined without revealing any information about possible sensitive or proprietary information contained in the genetic materials being declared under a verification regime. This study indicates that a verification regime could be constructed using a small number of pathogens that spans the range of known biological weapons agents. Since the number of possible pathogens is small it is possible and prudent to treat these pathogens as analogies to attributes in a nuclear verification regime. This study has determined that there may be some information that needs to be protected in a biological weapons control verification regime. To protect this information, the study concludes that the Lawrence Livermore Microbial Detection Array may be a suitable technology for the detection of the genetic information associated with the various pathogens. In addition, it has been determined that a suitable information barrier could be applied to this technology when the verification regime has been defined. Finally, the report posits a path forward for additional development of information barriers in a biological weapons verification regime. This path forward has shown that a new analysis approach coined as Information Loss Analysis might need to be pursued so that a numerical understanding of how information can be lost in specific measurement systems can be achieved.

  2. The central role of line tension in the fusion of biological membranes

    E-Print Network [OSTI]

    M. Schick; K. Katsov; M. Mueller

    2005-04-21T23:59:59.000Z

    Recent progress in the fusion of biological membranes is reviewed to highlight the central role played by the line tension, which permits exquisite control of the process.

  3. Viewing biology in action | EMSL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    biology in action Released: June 11, 2014 DOE-funded pilot program will create mesoscale biological imaging platform James Evans EMSL received first-year funding of almost...

  4. Todd Newberry: Professor of Biology

    E-Print Network [OSTI]

    Newberry, Andrew Todd; Jarrell, Randall; Regional History Project, UCSC Library

    2006-01-01T23:59:59.000Z

    Professor of Biology: Early Retirement page 44 Jarrell: ToProfessor of Biology: Early Retirement page 45 Jarrell: ToWar 33 Voluntary Early Retirement Incentive Program (VERIP)

  5. Biological Interactions and Dynamics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    proactive "EMSL 2.0-style" research paradigm. Because of the rapid pace of modern genomics and systems biology research, it is necessary to respond rapidly and flexibly to...

  6. Work with Biological Materials

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Work with Biological Materials Print Planning A complete Experiment Safety Sheet (ESS) is required before work can be done at the ALS. This ESS is either a part of the proposal...

  7. Modeling And Control Of Articulated Vehicles

    E-Print Network [OSTI]

    Chen, Chieh; Tomizuka, Masayoshi

    1997-01-01T23:59:59.000Z

    Modeling, Advanced Vehicle Control Systems, Lateral control, SteeringSteering and Braking Control of Heavy Duty Vehicles. Under this project, dynamic modeling

  8. Worldwide report: Arms control, [May 29, 1987

    SciTech Connect (OSTI)

    NONE

    1987-05-29T23:59:59.000Z

    This report contains information concerning arms control of the USSR. Topics include: (1) intermediate range nuclear forces, (2) chemical and biological weapons, and (3) related issues.

  9. 7th Annual Systems Biology Symposium: Systems Biology and Engineering

    SciTech Connect (OSTI)

    Galitski, Timothy P.

    2008-04-01T23:59:59.000Z

    Systems biology recognizes the complex multi-scale organization of biological systems, from molecules to ecosystems. The International Symposium on Systems Biology has been hosted by the Institute for Systems Biology in Seattle, Washington, since 2002. The annual two-day event gathers the most influential researchers transforming biology into an integrative discipline investingating complex systems. Engineering and application of new technology is a central element of systems biology. Genome-scale, or very small-scale, biological questions drive the enigneering of new technologies, which enable new modes of experimentation and computational analysis, leading to new biological insights and questions. Concepts and analytical methods in engineering are now finding direct applications in biology. Therefore, the 2008 Symposium, funded in partnership with the Department of Energy, featured global leaders in "Systems Biology and Engineering."

  10. Biological effectiveness of neutrons: Research needs

    SciTech Connect (OSTI)

    Casarett, G.W.; Braby, L.A.; Broerse, J.J.; Elkind, M.M.; Goodhead, D.T.; Oleinick, N.L.

    1994-02-01T23:59:59.000Z

    The goal of this report was to provide a conceptual plan for a research program that would provide a basis for determining more precisely the biological effectiveness of neutron radiation with emphasis on endpoints relevant to the protection of human health. This report presents the findings of the experts for seven particular categories of scientific information on neutron biological effectiveness. Chapter 2 examines the radiobiological mechanisms underlying the assumptions used to estimate human risk from neutrons and other radiations. Chapter 3 discusses the qualitative and quantitative models used to organize and evaluate experimental observations and to provide extrapolations where direct observations cannot be made. Chapter 4 discusses the physical principles governing the interaction of radiation with biological systems and the importance of accurate dosimetry in evaluating radiation risk and reducing the uncertainty in the biological data. Chapter 5 deals with the chemical and molecular changes underlying cellular responses and the LET dependence of these changes. Chapter 6, in turn, discusses those cellular and genetic changes which lead to mutation or neoplastic transformation. Chapters 7 and 8 examine deterministic and stochastic effects, respectively, and the data required for the prediction of such effects at different organizational levels and for the extrapolation from experimental results in animals to risks for man. Gaps and uncertainties in this data are examined relative to data required for establishing radiation protection standards for neutrons and procedures for the effective and safe use of neutron and other high-LET radiation therapy.

  11. Computational Biology and High Performance Computing 2000

    SciTech Connect (OSTI)

    Simon, Horst D.; Zorn, Manfred D.; Spengler, Sylvia J.; Shoichet, Brian K.; Stewart, Craig; Dubchak, Inna L.; Arkin, Adam P.

    2000-10-19T23:59:59.000Z

    The pace of extraordinary advances in molecular biology has accelerated in the past decade due in large part to discoveries coming from genome projects on human and model organisms. The advances in the genome project so far, happening well ahead of schedule and under budget, have exceeded any dreams by its protagonists, let alone formal expectations. Biologists expect the next phase of the genome project to be even more startling in terms of dramatic breakthroughs in our understanding of human biology, the biology of health and of disease. Only today can biologists begin to envision the necessary experimental, computational and theoretical steps necessary to exploit genome sequence information for its medical impact, its contribution to biotechnology and economic competitiveness, and its ultimate contribution to environmental quality. High performance computing has become one of the critical enabling technologies, which will help to translate this vision of future advances in biology into reality. Biologists are increasingly becoming aware of the potential of high performance computing. The goal of this tutorial is to introduce the exciting new developments in computational biology and genomics to the high performance computing community.

  12. Novel mechanisms of endothelial-epithelial interactions underlying cancer metastasis

    E-Print Network [OSTI]

    Connor, Yamicia Doyasi

    2013-01-01T23:59:59.000Z

    Elucidation of molecular mechanisms underlying metastasis is the final frontier in cancer biology research. Identifying individual pathways in the metastatic cascade could lead to development of metastasis-specific ...

  13. Nuclear reactor control apparatus

    SciTech Connect (OSTI)

    Sridhar, B.N.

    1981-08-28T23:59:59.000Z

    Nuclear reactor core safety rod release apparatus comprises a control rod having a detent notch in the form of an annular peripheral recess at its upper end, a control rod support tube for raising and lowering the control rod under normal conditions, latches pivotally mounted on the control support tube with free ends thereof normally disposed in the recess in the control rod, and cam means for pivoting the latches out of the recess in the control rod when a scram condition occurs. One embodiment of the invention comprises an additonal magnetically-operated latch for releasing the control rod under two different conditions, one involving seismic shock.

  14. Nuclear reactor control apparatus

    DOE Patents [OSTI]

    Sridhar, Bettadapur N. (Cupertino, CA)

    1983-11-01T23:59:59.000Z

    Nuclear reactor core safety rod release apparatus comprises a control rod having a detent notch in the form of an annular peripheral recess at its upper end, a control rod support tube for raising and lowering the control rod under normal conditions, latches pivotally mounted on the control support tube with free ends thereof normally disposed in the recess in the control rod, and cam means for pivoting the latches out of the recess in the control rod when a scram condition occurs. One embodiment of the invention comprises an additional magnetically-operated latch for releasing the control rod under two different conditions, one involving seismic shock.

  15. Use of Institutional Controls

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2003-04-09T23:59:59.000Z

    The Policy ensures that the Department of Energy will use institutional controls in the management of resources, facilities and properties under its control, and in implementing its programmatic responsibilities. Certified 1-28-11.

  16. Generalized Linear Quadratic Control

    E-Print Network [OSTI]

    Gattami, Ather Said

    We consider the problem of stochastic finite- and infinite-horizon linear quadratic control under power constraints. The calculations of the optimal control law can be done off-line as in the classical linear quadratic ...

  17. Bioforensics: Characterization of biological weapons agents by NanoSIMS

    SciTech Connect (OSTI)

    Weber, P K; Ghosal, S; Leighton, T J; Wheeler, K E; Hutcheon, I D

    2007-02-26T23:59:59.000Z

    The anthrax attacks of Fall 2001 highlight the need to develop forensic methods based on multiple identifiers to determine the origin of biological weapons agents. Genetic typing methods (i.e., DNA and RNA-based) provide one attribution technology, but genetic information alone is not usually sufficient to determine the provenance of the material. Non-genetic identifiers, including elemental and isotopic signatures, provide complementary information that can be used to identify the means, geographic location and date of production. Under LDRD funding, we have successfully developed the techniques necessary to perform bioforensic characterization with the NanoSIMS at the individual spore level. We have developed methods for elemental and isotopic characterization at the single spore scale. We have developed methods for analyzing spore sections to map elemental abundance within spores. We have developed rapid focused ion beam (FIB) sectioning techniques for spores to preserve elemental and structural integrity. And we have developed a high-resolution depth profiling method to characterize the elemental distribution in individual spores without sectioning. We used these newly developed methods to study the controls on elemental abundances in spores, characterize the elemental distribution of in spores, and to study elemental uptake by spores. Our work under this LDRD project attracted FBI and DHS funding for applied purposes.

  18. Nonlineai Control of Biotechnological Processes with Growth-Production Decoupling

    E-Print Network [OSTI]

    Bastin, Georges

    , for instance, to substrate overload- ing. Typical examples involve biological wastewater treatment processes Nonlinear control design techniques for a class of continuous biological processes with growth growth and the product formation. The issue of feedback linearizing control of biological reactors has

  19. Collection Policy: BIOCHEMISTRY, MOLECULAR AND CELL BIOLOGY Subject Scope | Priority Tables | Other policies . . .

    E-Print Network [OSTI]

    Angenent, Lars T.

    , recombinant DNA and its applications, metabolism, molecular biology, computer graphics in molecular biology regulation and chromatin structure in eukaryotes q Regulation of the heat shock genes q Control of gene-response regulatory protein in bacteria q Bacterial transcription mechanisms, especially termination, and control

  20. Fishery Biology Graduate Programs

    E-Print Network [OSTI]

    Fishery Biology Graduate Programs University of Alaska Fairbanks, Alaska 997750820 Program/degrees/index.html University of Arizona Tucson, Arizona 95721 Program: Fisheries Conservation and Management http://ag.arizona.edu/srnr/academicprograms/wildlifefisheries/gradstudiesFisheries.html Auburn University Auburn, Alabama 368490001 Programs: Aquaculture, Aquatic Ecology, Fishery Management

  1. BIOLOGICAL ANALYSIS Mass Spectrometry

    E-Print Network [OSTI]

    Greenaway, Alan

    Microscope) Analytical Equipment · High Performance Liquid Chromatography · Fast Protein Liquid Chromatography · Gas Chromatography · GC/MS · Elemental Analyser Molecular Biology Equipment · Biorad PCR Machine reactor for scale up studies In-line Particle sizers Rheometers Separation tanks Oscillating column (4m

  2. Chemistry and Chemical Biology

    E-Print Network [OSTI]

    Linhardt, Robert J.

    and interdisciplinary areas, including biochemical solar energy research, artificial photosynthesis and bio Biology at Rensselaer invites applications from students interested in pursuing a Ph.D. degree in an interdisciplinary environment with research opportunities in emerging fields, such as energy and the environment

  3. Biological and Environmental

    E-Print Network [OSTI]

    and sustainable biofuel but will also advance our understanding in areas of fundamental biological science. After capitalize on recent technological and scientific advances. Several multidisciplinary projects of key,ecosystemmonitoringandrestoration,combiningcropresearchandmicrobial engineering to make biofuels a viable alternative to fossil fuels, and personalized medicine to improve health

  4. Biological and Environmental Research

    E-Print Network [OSTI]

    recalcitrance. Using an integrated approach to solving the challenge of producing biofuel from cellulosic materials, the center will not only provide the scientific basis for affordable and sustainable biofuel but will also advance our understanding in areas of fundamental biological science. BESC researchers have

  5. CANCER BIOLOGY Infectioustumourcells

    E-Print Network [OSTI]

    Nowak, Martin A.

    CANCER BIOLOGY Infectioustumourcells David Dingli and Martin A. Nowak Cancer cells are generally infectious agents and be transmitted between individuals. The current view of cancer development is that normal cells are transformed into tumour cells by sequential mutations that activate cancer- promoting

  6. ECOLOGY LABORATORY BIOLOGY 341

    E-Print Network [OSTI]

    Vonessen, Nikolaus

    Page 1 ECOLOGY LABORATORY BIOLOGY 341 Fall Semester 2008 Bighorn Sheep Rams at Bison Range National ecological data; and 3) oral and written communication skills. Thus, these ecology labs, and statistical analyses appropriate for ecological data. A major goal of this class will be for you to gain

  7. Roadmap: Environmental and Conservation Biology Conservation Biology Bachelor of Science

    E-Print Network [OSTI]

    Sheridan, Scott

    Roadmap: Environmental and Conservation Biology ­Conservation Biology Bachelor of Science [AS Geology Elective 3-4 See note 2 on page 2 General Elective 4 #12;Roadmap: Environmental and Conservation Summary on page 2 Conservation Biology Concentration Elective 2 See note 3 on page 2 Semester Five: [15

  8. Guest Editors' Introduction: Synthetic Biology

    E-Print Network [OSTI]

    Densmore, Douglas

    + undergraduate participants from around the world. Synthetic Biology had a global market which gene- rated $233 Tufts University h SYNTHETIC BIOLOGY IS trending, as evidenced by the recent achievements in biofuels

  9. Experiment design for systems biology

    E-Print Network [OSTI]

    Apgar, Joshua Farley

    2009-01-01T23:59:59.000Z

    Mechanism-based chemical kinetic models are increasingly being used to describe biological signaling. Such models serve to encapsulate current understanding of pathways and to enable insight into complex biological processes. ...

  10. Modular architecture in biological networks

    E-Print Network [OSTI]

    Ramachandran, Gopal (Gopal Sebastian)

    2007-01-01T23:59:59.000Z

    In the past decade, biology has been revolutionized by an explosion in the availability of data. Translating this new wealth of information into meaningful biological insights and clinical breakthroughs will require a ...

  11. Biological Engineering integrates life sciences

    E-Print Network [OSTI]

    Walter, M.Todd

    mitigating 40 million pounds of carbon dioxide greenhouse gases each year, and would pay for itself in les with the constantly evolving science of biology, the field of Biological Engineering tackles local, national

  12. Biological Interactions and Dynamics Workshop | EMSL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biological Interactions and Dynamics Workshop Biological Interactions and Dynamics Workshop Wiley HS, Kaplan S. 2011. "Biological Interactions and Dynamics Science Theme Advisory...

  13. 2013 Biological Hydrogen Production Workshop Summary Report ...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Biological Hydrogen Production Workshop Summary Report 2013 Biological Hydrogen Production Workshop Summary Report November 2013 summary report for the 2013 Biological Hydrogen...

  14. Environmental Biology | Clean Energy | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    microbiology, biogeochemistry, molecular biology, molecular dynamics, bioinformatics, genomics, neutron science, chemistry, and computing-and spans multiple scales, from the...

  15. Systems Biology | Clean Energy | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of interdisciplinary scientists. Additional systems biology resources Research Highlights Media Mentions Publications Newsletters Biosciences Division Recent news releases 11...

  16. Perspectives Computational Biology in Brazil

    E-Print Network [OSTI]

    Neshich, Goran

    Perspectives Computational Biology in Brazil Goran Neshich Introduction At the request of the PLoS Computational Biology Editor-in- Chief, I agreed to write about computational biology in Brazil (see author of the field itself is short); b) the current state of the field in Brazil; c) the influence of computational

  17. COMPUTATIONAL MOLECULAR BIOLOGY TRAINING PROGRAM

    E-Print Network [OSTI]

    Mayfield, John

    in the burgeoning fields of bioinformatics and computational biology. A major outcome of the initial funding period was the establishment of ISU's interdepartmental graduate program in Bioinformatics and Computational Biology (BCB for Research Excellence in Bioinformatics and Computational Biology (BCB). The ISU-NMSU partnership

  18. Controlling Fleas

    E-Print Network [OSTI]

    Merchant, Michael E.; Robinson, James V.

    2006-12-18T23:59:59.000Z

    Controlling Fleas Mike Merchant and James Robinson* F leas are small, wingless insects that feed on the blood of animals and people. Americans spend about $9 billion a year controlling fleas ? one of the biggest expenses for pet owners. In Texas... pet bedding regularly and vacuum thoroughly. Vacuuming removes up to 30 per- cent of the larvae and up to 60 percent of flea eggs from a carpet, as well as the larvae?s food supply of dried blood. Vacuum under furniture, cushions, chairs, beds...

  19. 7.013 Introductory Biology, Spring 2005

    E-Print Network [OSTI]

    Sive, Hazel L.

    The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological ...

  20. Autofermentative Biological Hydrogen Production by Cyanobacteria...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Autofermentative Biological Hydrogen Production by Cyanobacteria Autofermentative Biological Hydrogen Production by Cyanobacteria Presentation by Charles Dismukes, Rutgers...

  1. Systems and Control Engineering

    E-Print Network [OSTI]

    Rollins, Andrew M.

    ), the automobile companies Ford, GM) computer companies (IBM, Lucent, Bellcore) by the aerospace industry (GE, JPL areas require cross-disciplinary tools and methods for their solution. The Bachelor of Science program include the modeling, analysis, optimization and control of complex biological, energy, and industrial

  2. Physics of biological evolution 

    E-Print Network [OSTI]

    Court, Steven James

    2014-11-27T23:59:59.000Z

    Part I: A remarkable feature of life on Earth is that despite the apparent observed diversity, the underlying chemistry that powers it is highly conserved. From the level of the nucleobases, through the amino acids and ...

  3. Biological and Environmental Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625govInstrumentstdmadapInactiveVisiting the TWP TWPAlumniComplexMaterialProductionBiological and

  4. Biology | More Science | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625govInstrumentstdmadapInactiveVisiting the TWP TWPAlumniComplexMaterialProductionBiologicalLaboratories

  5. UC Merced Center for Computational Biology Final Report

    SciTech Connect (OSTI)

    Colvin, Michael; Watanabe, Masakatsu

    2010-11-30T23:59:59.000Z

    Final report for the UC Merced Center for Computational Biology. The Center for Computational Biology (CCB) was established to support multidisciplinary scientific research and academic programs in computational biology at the new University of California campus in Merced. In 2003, the growing gap between biology research and education was documented in a report from the National Academy of Sciences, Bio2010 Transforming Undergraduate Education for Future Research Biologists. We believed that a new type of biological sciences undergraduate and graduate programs that emphasized biological concepts and considered biology as an information science would have a dramatic impact in enabling the transformation of biology. UC Merced as newest UC campus and the first new U.S. research university of the 21st century was ideally suited to adopt an alternate strategy - to create a new Biological Sciences majors and graduate group that incorporated the strong computational and mathematical vision articulated in the Bio2010 report. CCB aimed to leverage this strong commitment at UC Merced to develop a new educational program based on the principle of biology as a quantitative, model-driven science. Also we expected that the center would be enable the dissemination of computational biology course materials to other university and feeder institutions, and foster research projects that exemplify a mathematical and computations-based approach to the life sciences. As this report describes, the CCB has been successful in achieving these goals, and multidisciplinary computational biology is now an integral part of UC Merced undergraduate, graduate and research programs in the life sciences. The CCB began in fall 2004 with the aid of an award from U.S. Department of Energy (DOE), under its Genomes to Life program of support for the development of research and educational infrastructure in the modern biological sciences. This report to DOE describes the research and academic programs made possible by the CCB from its inception until August, 2010, at the end of the final extension. Although DOE support for the center ended in August 2010, the CCB will continue to exist and support its original objectives. The research and academic programs fostered by the CCB have led to additional extramural funding from other agencies, and we anticipate that CCB will continue to provide support for quantitative and computational biology program at UC Merced for many years to come. Since its inception in fall 2004, CCB research projects have continuously had a multi-institutional collaboration with Lawrence Livermore National Laboratory (LLNL), and the National Center for Supercomputing Applications at the University of Illinois at Urbana-Champaign, as well as individual collaborators at other sites. CCB affiliated faculty cover a broad range of computational and mathematical research including molecular modeling, cell biology, applied math, evolutional biology, bioinformatics, etc. The CCB sponsored the first distinguished speaker series at UC Merced, which had an important role is spreading the word about the computational biology emphasis at this new campus. One of CCB's original goals is to help train a new generation of biologists who bridge the gap between the computational and life sciences. To archive this goal, by summer 2006, a new program - summer undergraduate internship program, have been established under CCB to train the highly mathematical and computationally intensive Biological Science researchers. By the end of summer 2010, 44 undergraduate students had gone through this program. Out of those participants, 11 students have been admitted to graduate schools and 10 more students are interested in pursuing graduate studies in the sciences. The center is also continuing to facilitate the development and dissemination of undergraduate and graduate course materials based on the latest research in computational biology.

  6. Methods of increasing secretion of polypeptides having biological activity

    DOE Patents [OSTI]

    Merino, Sandra

    2014-05-27T23:59:59.000Z

    The present invention relates to methods for producing a secreted polypeptide having biological activity, comprising: (a) transforming a fungal host cell with a fusion protein construct encoding a fusion protein, which comprises: (i) a first polynucleotide encoding a signal peptide; (ii) a second polynucleotide encoding at least a catalytic domain of an endoglucanase or a portion thereof; and (iii) a third polynucleotide encoding at least a catalytic domain of a polypeptide having biological activity; wherein the signal peptide and at least the catalytic domain of the endoglucanase increases secretion of the polypeptide having biological activity compared to the absence of at least the catalytic domain of the endoglucanase; (b) cultivating the transformed fungal host cell under conditions suitable for production of the fusion protein; and (c) recovering the fusion protein, a component thereof, or a combination thereof, having biological activity, from the cultivation medium.

  7. Methods of increasing secretion of polypeptides having biological activity

    DOE Patents [OSTI]

    Merino, Sandra

    2014-10-28T23:59:59.000Z

    The present invention relates to methods for producing a secreted polypeptide having biological activity, comprising: (a) transforming a fungal host cell with a fusion protein construct encoding a fusion protein, which comprises: (i) a first polynucleotide encoding a signal peptide; (ii) a second polynucleotide encoding at least a catalytic domain of an endoglucanase or a portion thereof; and (iii) a third polynucleotide encoding at least a catalytic domain of a polypeptide having biological activity; wherein the signal peptide and at least the catalytic domain of the endoglucanase increases secretion of the polypeptide having biological activity compared to the absence of at least the catalytic domain of the endoglucanase; (b) cultivating the transformed fungal host cell under conditions suitable for production of the fusion protein; and (c) recovering the fusion protein, a component thereof, or a combination thereof, having biological activity, from the cultivation medium.

  8. Methods of increasing secretion of polypeptides having biological activity

    DOE Patents [OSTI]

    Merino, Sandra

    2013-10-01T23:59:59.000Z

    The present invention relates to methods for producing a secreted polypeptide having biological activity, comprising: (a) transforming a fungal host cell with a fusion protein construct encoding a fusion protein, which comprises: (i) a first polynucleotide encoding a signal peptide; (ii) a second polynucleotide encoding at least a catalytic domain of an endoglucanase or a portion thereof; and (iii) a third polynucleotide encoding at least a catalytic domain of a polypeptide having biological activity; wherein the signal peptide and at least the catalytic domain of the endoglucanase increases secretion of the polypeptide having biological activity compared to the absence of at least the catalytic domain of the endoglucanase; (b) cultivating the transformed fungal host cell under conditions suitable for production of the fusion protein; and (c) recovering the fusion protein, a component thereof, or a combination thereof, having biological activity, from the cultivation medium.

  9. Unraveling pancreatic islet biology by quantitative proteomics

    SciTech Connect (OSTI)

    Zhou, Jianying; Dann, Geoffrey P.; Liew, Chong W.; Smith, Richard D.; Kulkarni, Rohit N.; Qian, Weijun

    2011-08-01T23:59:59.000Z

    The pancreatic islets of Langerhans play a critical role in maintaining blood glucose homeostasis by secreting insulin and several other important peptide hormones. Impaired insulin secretion due to islet dysfunction is linked to the pathogenesis underlying both Type 1 and Type 2 diabetes. Over the past 5 years, emerging proteomic technologies have been applied to dissect the signaling pathways that regulate islet functions and gain an understanding of the mechanisms of islet dysfunction relevant to diabetes. Herein, we briefly review some of the recent quantitative proteomic studies involving pancreatic islets geared towards gaining a better understanding of islet biology relevant to metabolic diseases.

  10. Biological investigations of the Sandia National Laboratories Sol se Mete Aerial Cable Facility

    SciTech Connect (OSTI)

    Sullivan, R.M.

    1994-10-01T23:59:59.000Z

    This report provides results of a comprehensive biological field survey performed on the Sandia National Laboratories Aerial Cable Facility, at the east end of Kirtland Air Force Base (KAFB), Bernalillo County, New Mexico. This survey was conducted late September through October, 1991. ACF occupies a 440-acre tract of land withdrawn by the US Forest Service (USFS) for use by KAFB, and in turn placed under operational control of SNL by the Department of Energy (DOE). All land used by SNL for ACF is part of a 15,851-acre tract of land withdrawn by the US Forest Service. In addition, a number of different organizations use the 15,851-acre area. The project area used by SNL encompasses portions of approximately six sections (3,840 acres) of US Forest Service land located within the foothills of the west side of the Manzano Mountains (East Mesa). The biological study area is used by the KAFB, the US Department of Interior, and SNL. This area includes: (1) Sol se Mete Springs and Canyon, (2) East Anchor Access Road, (3) East Anchor Site, (4) Rocket Sled Track, (5) North Arena, (6) East Instrumentation Site and Access Road, (7) West Anchor Access Road, (8) West Anchor Site, (9) South Arena, (10) Winch Sites, (11) West Instrumentation Sites, (12) Explosive Assembly Building, (13) Control Building, (14) Lurance Canyon Road and vicinity. Although portions of approximately 960 acres of withdrawn US Forest Service land have been altered, only 700 acres have been disturbed by activities associated with ACF; approximately 2,880 acres consist of natural habitat. Absence of grazing by livestock and possibly native ungulates, and relative lack of human disturbance have allowed this area to remain in a more natural vegetative state relative to the condition of private range lands throughout New Mexico. This report evaluates threatened and endangered species found on ACF, as well as a comprehensive assessment of biological habitats.

  11. Concentration Gradient and Information Energy for Decentralized UAV Control1

    E-Print Network [OSTI]

    Mohseni, Kamran

    spills, industrial release accidents, or chemical/biological/nuclear terrorist attacks. DependingConcentration Gradient and Information Energy for Decentralized UAV Control1 William J. Pisano2

  12. Department of Systems Biology & Bioinformatics

    E-Print Network [OSTI]

    Rostock, Universität

    Department of Systems Biology & Bioinformatics Faculty of Computer Sciences & Electrical, comparability and fairness. Practical Aspects and Soft Skills Technical Achievement Background understanding

  13. Biological & Environmental Research Abstracts Database

    Office of Scientific and Technical Information (OSTI)

    Welcome to the Administrative section of the Biological and Environmental Research Abstracts Database. Please logon. Logon Name: Password: Logon CommentsEmail Us * Security...

  14. CollegeofScience Biological Sciences

    E-Print Network [OSTI]

    Hickman, Mark

    ,populations,and even ecosystems. Our courses will help prepare you for a career in biology,be it in biodiversity

  15. COMPLEX BIOLOGICAL MECHANISMS: CYCLIC, OSCILLATORY,

    E-Print Network [OSTI]

    Bechtel, William

    COMPLEX BIOLOGICAL MECHANISMS: CYCLIC, OSCILLATORY, AND AUTONOMOUS William Bechtel and Adele- nomological framework and its focus on laws as the primary explanatory vehicle; for them, a scientific

  16. KPFM and PFM of Biological Systems

    SciTech Connect (OSTI)

    Rodriguez, Brian [University College, Dublin; Kalinin, Sergei V [ORNL

    2011-01-01T23:59:59.000Z

    Surface potentials and electrostatic interactions in biological systems are a key element of cellular regulation and interaction. Examples include cardiac and muscular activity, voltage-gated ion channels, protein folding and assembly, and electroactive cells and electrotransduction. The coupling between electrical, mechanical, and chemical signals and responses in cellular systems necessitates the development of tools capable of measuring the distribution of charged species, surface potentials, and mechanical responses to applied electrical stimuli and vice versa, ultimately under physiological conditions. In this chapter, applications of voltage-modulated atomic force microscopy (AFM) methods including Kelvin probe force microscopy (KPFM) and piezoresponse force microscopy (PFM) to biological systems are discussed. KPFM is a force-sensitive non-contact or intermittent-contact mode AFM technique that allows electrostatic interactions and surface potentials to be addressed. Beyond long-range electrostatic interactions, the application of bias can lead to a mechanical response, e.g., due to linear piezoelectric coupling in polar biopolymers or via more complex electrotransduction and redox pathways in other biosystems. The use and development of PFM, based on direct electromechanical detection, to biological systems will also be addressed. The similarities and limitations of measuring surface potentials and electromechanical coupling in solution will be outlined.

  17. NH Acid Rain Control Act (New Hampshire)

    Broader source: Energy.gov [DOE]

    The Act is implemented under New Hampshire's acid deposition control program established under the Rules to Control Air Pollution in Chapter Env-A 400. The goal of the Act is to reduce emissions...

  18. Using Compost for Erosion Control and Revegetation 

    E-Print Network [OSTI]

    Mukhtar, Saqib

    2005-08-08T23:59:59.000Z

    Composting refers to the biological decomposition and stabilization of organic materials by microorganisms under aerobic conditions. Compost from various materials (yard trimmings, manure, food processing residuals and other organic materials) has...

  19. Recommendations for Analyzing Accidents under the National Environment...

    Energy Savers [EERE]

    Such safeguards would minimize the possibility of sabotage and facilitate the recovery of spent nuclear fuel shipments that could come under control of unauthorized...

  20. Computational Molecular Biology of Genome Expression and Regulation

    E-Print Network [OSTI]

    Computational Molecular Biology of Genome Expression and Regulation Michael Q. Zhang, Ph.D. Cold in genome expression and regulation network in which better modern statistical and machine learning referring to the cellular processes that lead to pro- tein production, is controlled and regulated

  1. Biology and Management of Fungal Pathogens of Vegetables Program Leader

    E-Print Network [OSTI]

    Lazzaro, Brian

    of cucurbit and solanaceous crops. This water mold was recently found on snap beans in New York on Long Island Summary: Biology and management of Sclerotinia sclerotiorum (cause of white mold) on beans (snap, soy strategies for control of Phytophthora capsici on snap beans (cause of Phytophthora blight), including

  2. Staunton State Park Biological Inventory

    E-Print Network [OSTI]

    Staunton State Park Biological Inventory Prepared by: Susan Spackman, David Anderson, Jeremy Biological Inventory Prepared by: Susan Spackman, David Anderson, Jeremy Siemers, Phyllis Pineda, and Jill. The information management staff with CNHP was responsible for integrating the data resulting from the inventory

  3. FISHERY RESEARCH BIOLOGICAL LABORATORY, GALVESTON

    E-Print Network [OSTI]

    stations conduct fish ry re - search in the Gulf of Mexico as part of the work of the Bureau's Gulf, St. Pet rsburg Beach, Fla. Biological Res earch Biological Laboratory, Beaufort, N. C hw Gulf of Mexico Abundance of postlarval and juv nil shrimp Pink shrimp life history . Brown

  4. Purdue extension Agricultural&Biological

    E-Print Network [OSTI]

    for an extended period and encourage biological treatment to minimize organic matter (BOD), nitrogenPurdue extension Don Jones Agricultural&Biological Engineering Alan Sutton AnimalSciences Purdue structures must be designed and managed to contain manure, wastewater, contaminated runoff, and ma- nure

  5. Detection and treatment of chemical weapons and/or biological pathogens

    DOE Patents [OSTI]

    Mariella Jr., Raymond P.

    2004-09-07T23:59:59.000Z

    A system for detection and treatment of chemical weapons and/or biological pathogens uses a detector system, an electrostatic precipitator or scrubber, a circulation system, and a control. The precipitator or scrubber is activated in response to a signal from the detector upon the detection of chemical weapons and/or biological pathogens.

  6. Engineering of metabolic control

    DOE Patents [OSTI]

    Liao, James C.

    2004-03-16T23:59:59.000Z

    The invention features a method of producing heterologous molecules in cells under the regulatory control of a metabolite and metabolic flux. The method can enhance the synthesis of heterologous polypeptides and metabolites.

  7. Engineering of metabolic control

    DOE Patents [OSTI]

    Liao, James C.

    2006-10-17T23:59:59.000Z

    The invention features a method of producing heterologous molecules in cells under the regulatory control of a metabolite and metabolic flux. The method can enhance the synthesis of heterologous polypeptides and metabolites.

  8. Unified analysis of terminal-time control in classical and quantum systems

    E-Print Network [OSTI]

    Alexander Pechen; Herschel Rabitz

    2010-11-04T23:59:59.000Z

    Many phenomena in physics, chemistry, and biology involve seeking an optimal control to maximize an objective for a classical or quantum system which is open and interacting with its environment. The complexity of finding an optimal control for maximizing an objective is strongly affected by the possible existence of sub-optimal maxima. Within a unified framework under specified conditions, control objectives for maximizing at a terminal time physical observables of open classical and quantum systems are shown to be inherently free of sub-optimal maxima. This attractive feature is of central importance for enabling the discovery of controls in a seamless fashion in a wide range of phenomena transcending the quantum and classical regimes.

  9. 6/06/09 BS in Biology, Concentration in Microbiology Bachelor of Science in Biology: Concentration in Microbiology

    E-Print Network [OSTI]

    been hired as quality control microbiologists or as research technicians and associates in hospitals Biometry 4 Total lower-division requirements 35-36 Upper-Division Requirements (33 units) BIO 355 Genetics 11 Total upper-division requirements 33 Total for major 68-69 The Department of Biology

  10. Comparative Microbial Genomics group CenterforBiologicalSequenceanalysisDepartmentofSystemsBiology

    E-Print Network [OSTI]

    Ussery, David W.

    Comparative Microbial Genomics group CenterforBiologicalSequenceanalysisDepartmentofSystemsBiology Visualisation of Large Amounts of Data Dave Ussery 27 February, 2008 #12;Comparative Microbial Genomics group CenterforBiologicalSequenceanalysisDepartmentofSystemsBiology #12;Comparative Microbial Genomics group

  11. Loop Quantum Theory Applied to Biology and Nonlinear Whole Biology

    E-Print Network [OSTI]

    Yi-Fang Chang

    2008-01-02T23:59:59.000Z

    The loop quantum theory, which constitutes a very small discontinuous space, as new method is applied to biology. The model of protein folding and lungs is proposed. In the model, some known results are used, and four approximate conclusions are obtained: their structures are quantized, their space regions are finite, various singularities correspond to folding and crossed points, and different types of catastrophe exist. Further, based on the inseparability and correlativity of the biological systems, the nonlinear whole biology is proposed, and four basic hypotheses are formed. It may unify reductionism and holism, structuralism and functionalism. Finally, the medical meaning of the theory is discussed briefly.

  12. Model membranes as a tool for biological studies and biosensor applications

    E-Print Network [OSTI]

    Armendariz, Kevin P.

    2013-12-31T23:59:59.000Z

    The biological membrane is a fundamental cellular structure which forms the natural selective barrier separating cells from their environment. Model membranes have long been employed to study these complicated structures in controlled environments...

  13. Mesangial cell biology

    SciTech Connect (OSTI)

    Abboud, Hanna E., E-mail: Abboud@uthscsa.edu

    2012-05-15T23:59:59.000Z

    Mesangial cells originate from the metanephric mesenchyme and maintain structural integrity of the glomerular microvascular bed and mesangial matrix homeostasis. In response to metabolic, immunologic or hemodynamic injury, these cells undergo apoptosis or acquire an activated phenotype and undergo hypertrophy, proliferation with excessive production of matrix proteins, growth factors, chemokines and cytokines. These soluble factors exert autocrine and paracrine effects on the cells or on other glomerular cells, respectively. MCs are primary targets of immune-mediated glomerular diseases such as IGA nephropathy or metabolic diseases such as diabetes. MCs may also respond to injury that primarily involves podocytes and endothelial cells or to structural and genetic abnormalities of the glomerular basement membrane. Signal transduction and oxidant stress pathways are activated in MCs and likely represent integrated input from multiple mediators. Such responses are convenient targets for therapeutic intervention. Studies in cultured MCs should be supplemented with in vivo studies as well as examination of freshly isolated cells from normal and diseases glomeruli. In addition to ex vivo morphologic studies in kidney cortex, cells should be studied in their natural environment, isolated glomeruli or even tissue slices. Identification of a specific marker of MCs should help genetic manipulation as well as selective therapeutic targeting of these cells. Identification of biological responses of MCs that are not mediated by the renin–angiotensin system should help development of novel and effective therapeutic strategies to treat diseases characterized by MC pathology.

  14. Bacterial Community Structure in Geographically Distributed Biological

    E-Print Network [OSTI]

    Alvarez-Cohen, Lisa

    Bacterial Community Structure in Geographically Distributed Biological Wastewater Treatment of the microbial communities within biological wastewater treatment reactors is incomplete due to limitations microbial community composition in five biological wastewater treatment reactors in China and the United

  15. Introduction to Bioinformatics A Systems Biology Approach

    E-Print Network [OSTI]

    Rocha, Luis

    Introduction to Bioinformatics A Systems Biology Approach Luis M. Rocha Complex Systems Modeling Computational Biology to Bioinformatics Course Layout: March 11-15, 2002 #12;P Systems Biology P Synthetic, Multi- Disciplinary Approach

  16. Method for biological purification

    DOE Patents [OSTI]

    Lucido, John A. (Mt. Sinai, NY); Keenan, Daniel (Rockville Centre, NY); Premuzic, Eugene T. (East Moriches, NY); Lin, Mow S. (Rocky Point, NY); Shelenkova, Ludmila (Yaphank, NY)

    2001-03-27T23:59:59.000Z

    An apparatus is disclosed for containing a microorganism culture in an active exponential growth and delivering a supply of microorganisms to an environment containing wastes for bio-augmenting the biodegradation of the wastes. The apparatus comprises a bioreactor and an operably connected controller. The bioreactor has a bioreactor chamber for containing a supply of microorganisms, a second chamber for containing a supply of water and inorganic nutrients, and a third chamber for containing a supply of organic nutrients. The bioreactor is operably connected to the controller in which a first pump is operably connected in fluid communication between the bioreactor chamber and the second chamber and third chamber, and a second pump is operably connected in fluid communication between the bioreactor chamber and the environment containing wastes to be biodegraded. The controller further includes a timer and regulator operably connected to the first and second pumps to effectively maintain the microorganisms in exponential growth in the bioreactor chamber and to deliver microorganisms to an environment to be treated. Also, disclosed is a method for bio-augmenting the biodegradation of wastes.

  17. Adaptive control for optimizing microalgae production

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Adaptive control for optimizing microalgae production Francis Mairet Rafael Mu for light-limited microalgae culture. This controller regulates the light absorption factor, defined productivity under day-night cycles. Keywords: Nonlinear controller, Microalgae, Optimization, Biomass

  18. Scaling Reinforcement Learning Paradigms for Motor Control 

    E-Print Network [OSTI]

    Vijayakumar, Sethu; Peters, Jan; Schaal, Stefan

    Reinforcement learning offers a general framework to explain reward related learning in artificial and biological motor control. However, current reinforcement learning methods rarely scale to high dimensional movement systems ...

  19. JPRS report: Arms control, [January 14, 1991

    SciTech Connect (OSTI)

    NONE

    1991-01-14T23:59:59.000Z

    This document contains articles from foreign periodicals that have been translated into English. The articles are about arms control. Topics include forces in Europe, nuclear forces, treaties, conferences, security, chemical and biological warfare and nuclear testing.

  20. EMG control of prosthetic ankle plantar flexion

    E-Print Network [OSTI]

    Wang, Jing, M. Eng. Massachusetts Institute of Technology

    2011-01-01T23:59:59.000Z

    Similar to biological human ankle, today's commercially available powered ankle-foot prostheses can vary impedance and deliver net positive ankle work. These commercially available prostheses are intrinsically controlled. ...

  1. DEPARTMENT OF BIOLOGY Hurricane Savitz Hits Florida

    E-Print Network [OSTI]

    Kelly, John J.

    DEPARTMENT OF BIOLOGY Hurricane Savitz Hits Florida (Photo Credit: Michael Masellis, Biology Major Hurricane Savitz Hits Florida Future Science Teachers' Club Recent Grant Successes Forthcoming Publications

  2. The sequestration efficiency of the biological pump

    E-Print Network [OSTI]

    DeVries, Tim; Primeau, Francois; Deutsch, Curtis

    2012-01-01T23:59:59.000Z

    Preformed phosphate, soft tissue pump and atmospheric CO 2 ,efficiency of the biological pump Tim DeVries, 1 Francoisproduces a “biological pump” that reduces the concentration

  3. Computational biology and high performance computing

    E-Print Network [OSTI]

    Shoichet, Brian

    2011-01-01T23:59:59.000Z

    Biology and High Performance Computing Manfred Zorn, TeresaBiology and High Performance Computing Presenters: Manfred99-Portland High performance computing has become one of the

  4. Synthetic biology and crop engineering

    Broader source: Energy.gov [DOE]

    Breakout Session 2: Frontiers and Horizons Session 2-A: Synthetic Biology and the Promise of Biofuels Jonathan Burbaum, Program Director, Department of Energy, Office of Science, ARPA–E

  5. Preparing for Transfer Biological Engineering

    E-Print Network [OSTI]

    Walter, M.Todd

    Environmental Engineering Game Design Industrial Systems & Information Technology Information Science MaterialsPreparing for Transfer Majors: Biological Engineering Chemical Engineering Civil Engineering Computer Science Electrical & Computer Engineering Engineering Physics Environmental Engineering

  6. BIOLOGICAL SAFETY POLICY PROGRAM TOPICS

    E-Print Network [OSTI]

    Fang-Yen, Christopher

    research protocols involving hazardous materials, reviews construction design for safety features with or near biologically hazardous materials (infectious agents, biohazards or recombinant DNA). 1.3 "Infectious waste" or "biohazardous waste" is defined by the Pennsylvania Department of Environmental

  7. Chemistry Division Department of Biological

    E-Print Network [OSTI]

    Heller, Barbara

    1 Chemistry Division Department of Biological and Chemical Sciences, Illinois Institute-13 Chemistry Division invites nominations for Kilpatrick Fellowship for the academic year 2012's Chemistry Department from 1947­1960. Mary Kilpatrick was a chemistry faculty member from 1947

  8. Modular design of biological systems

    E-Print Network [OSTI]

    Norville, Julie Erin, 1980-

    2012-01-01T23:59:59.000Z

    The focus of my research is the development of technology for building compound biological systems from simpler pieces. I designed BioScaffold parts, a family of variable regions that can be inserted into a DNA sequence ...

  9. Biological Science | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels Data Center HomeIdleBiological Science Biological Science The protozoan

  10. Microcomputers in Process Control

    E-Print Network [OSTI]

    Vinson, D. R.; Chatterjee, N.

    under optimum process conditions. The difference between the actual performance and the corresponding standard is the difference between "normal" and "best" performance. A computer system's objective is to minimize this difference. Control It has... program evolution, and provides a secure and distinct separation of higher level functions from lower level functions. The baseline control system is further divided into field signal transmission instrumentation and computer compatible controllers...

  11. Biological Systems for Hydrogen Photoproduction (Presentation)

    SciTech Connect (OSTI)

    Ghirardi, M. L.

    2012-05-01T23:59:59.000Z

    This presentation summarizes NREL biological systems for hydrogen photoproduction work for the DOE Hydrogen and Fuel Cells Program Annual Merit Review and Peer Evaluation Meeting, May 14-18, 2012. General goal is develop photobiological systems for large-scale, low cost and efficient H{sub 2} production from water (barriers AH, AI and AJ). Specific tasks are: (1) Address the O{sub 2} sensitivity of hydrogenases that prevent continuity of H{sub 2} photoproduction under aerobic, high solar-to-hydrogen (STH) light conversion efficiency conditions; and (2) Utilize a limited STH H{sub 2}-producing method (sulfur deprivation) as a platform to address or test other factors limiting commercial algal H{sub 2} photoproduction, including low rates due to biochemical and engineering mechanisms.

  12. Integrative Biology Keith A. Crandall, Chair

    E-Print Network [OSTI]

    Hart, Gus

    . The bioinformatics major is for students with interests in both the computer and the biological sciences. The degree merges these interests in the areas of bioinformatics and computational biology, giving students Programs and Degrees BS Bioinformatics BS Biology Composite Teaching BS Integrative Biology Students should

  13. Acceptance Criteria Framework for Autonomous Biological Detectors

    SciTech Connect (OSTI)

    Dzenitis, J M

    2006-12-12T23:59:59.000Z

    The purpose of this study was to examine a set of user acceptance criteria for autonomous biological detection systems for application in high-traffic, public facilities. The test case for the acceptance criteria was the Autonomous Pathogen Detection System (APDS) operating in high-traffic facilities in New York City (NYC). However, the acceptance criteria were designed to be generally applicable to other biological detection systems in other locations. For such detection systems, ''users'' will include local authorities (e.g., facility operators, public health officials, and law enforcement personnel) and national authorities [including personnel from the Department of Homeland Security (DHS), the BioWatch Program, the Centers for Disease Control and Prevention (CDC), and the Federal Bureau of Investigation (FBI)]. The panel members brought expertise from a broad range of backgrounds to complete this picture. The goals of this document are: (1) To serve as informal guidance for users in considering the benefits and costs of these systems. (2) To serve as informal guidance for developers in understanding the needs of users. In follow-up work, this framework will be used to systematically document the APDS for appropriateness and readiness for use in NYC.

  14. PACKAGE (Plasma Analysis, Chemical Kinetics and Generator Efficiency): a computer program for the calculation of partial chemical equilibrium/partial chemical rate controlled composition of multiphased mixtures under one dimensional steady flow

    SciTech Connect (OSTI)

    Yousefian, V.; Weinberg, M.H.; Haimes, R.

    1980-02-01T23:59:59.000Z

    The NASA CEC Code was the starting point for PACKAGE, whose function is to evaluate the composition of a multiphase combustion product mixture under the following chemical conditions: (1) total equilibrium with pure condensed species; (2) total equilibrium with ideal liquid solution; (3) partial equilibrium/partial finite rate chemistry; and (4) fully finite rate chemistry. The last three conditions were developed to treat the evolution of complex mixtures such as coal combustion products. The thermodynamic variable pairs considered are either pressure (P) and enthalpy, P and entropy, at P and temperature. Minimization of Gibbs free energy is used. This report gives detailed discussions of formulation and input/output information used in the code. Sample problems are given. The code development, description, and current programming constraints are discussed. (DLC)

  15. Biology and Medicine Division annual report, 1985

    SciTech Connect (OSTI)

    Not Available

    1986-04-01T23:59:59.000Z

    This book briefly describes the activities of the Biology and Medicine Division of the Lawrence Berkeley Laboratory. During the past year the Donner Pavilion program on the treatment of arteriovenous malformations in the brain has chalked up very significant successes. The disease control rate has been high and objective measures of success using cerebral angiography have been established. The new high resolution positron emitting tomographic imager has been demonstrated to operate successfully. In the Radiation Biophysics program, the availability of higher mass ions up to uranium has allowed us cell and tissue studies in a radiation domain that is entirely new. Using uranium beams, investigators have already made new and exciting findings that are described in the body of the report.

  16. A biological control study of Phymatotrichum root rot of cotton

    E-Print Network [OSTI]

    Freedman, Jerome Abraham

    1982-01-01T23:59:59.000Z

    ' 10 10 Mean 10 ' 10 10 Mean 10 10 10 Mean 10-' 10 10 Mean 10 10 10 Mean 10. 67 8. 89 11. 11 10. 22 0. 44 1. 11 22. 22 7. 93 2. 89 8. 89 22. 22 11. 33 5. 33 5. 56 0 3. 63 1. 00 0 0 0, 33 2. 19 10. 54 33. 33 1.... / HBC D1lution Trichoderma s DMRT Trichoderma Pseudomonas 10 10 10 Mean 10-' 10 10 Mean 3. 22 1. 56 1. 11 33. 33 0 0 1. 44 1. 64 1. 67 1. 00 4. 44 10. 14 0 0 2. 04 2. 25 10-' 10 10 Mean 1. 11 2. 22 0 1. 11 0. 93 4. 41 1. 11...

  17. Invited Invaders: Beetles used sucessfully in biological control of saltcedar

    E-Print Network [OSTI]

    Wythe, Kathy

    2011-01-01T23:59:59.000Z

    ?produced one of the worst ecological disasters in the recorded history of the region [western United States],? according to a #25;#24;#24;#24; review of the problem by Dr. Jack DeLoach, an ARS entomologist in Temple, and other scientists involved... Knutson, Texas AgriLife Extension Service entomologist at the Texas AgriLife Research and Extension Center at Dallas, released #16;#18; Crete (Greece) beetles at a research site along Beals Creek near Big Spring in West Texas. Over the summer...

  18. Invited Invaders: Beetles used successfully in biological control of saltcedar

    E-Print Network [OSTI]

    Wythe, Kathy

    2011-01-01T23:59:59.000Z

    ?produced one of the worst ecological disasters in the recorded history of the region [western United States],? according to a #25;#24;#24;#24; review of the problem by Dr. Jack DeLoach, an ARS entomologist in Temple, and other scientists involved... Knutson, Texas AgriLife Extension Service entomologist at the Texas AgriLife Research and Extension Center at Dallas, released #16;#18; Crete (Greece) beetles at a research site along Beals Creek near Big Spring in West Texas. Over the summer...

  19. Biology and chemical control of the spotted alfalfa aphid

    E-Print Network [OSTI]

    Downing, Douglas Holland

    1959-01-01T23:59:59.000Z

    , . 'ParathieO. , er sjstbyL. yaratbioe also sore'r'ended der', osa '-, ac tha'r'aca ef . ;l$ posed of, Social'tesfoaat yar: aero for . -', : -' , "" elecy'iito ointrol of, the. ipbid. , ; %ha as&de ievel rajl'in-. . hiiicRing' thebo -ioss@tioidas: se4...:. &rgea&ov'r &Lf, ~~?~. az. act~ 8&n ~), La . wgaet and coat' aboindiint ef 'erat', e dolmen'. Shit of:-". . . . ';"::. , '', ; " d~geedicij hCeer 'fLLaa fd~4 'Xn CalifdrnLIL. : The aadelta'-:, ". :u de ndc iat . aphidi;, b~t . gead 'on -ydllen, neater...

  20. Controlling Mobile Robots with Distributed Neuro-Biological Systems

    E-Print Network [OSTI]

    Weitzenfeld, Alfredo

    Dept, ITAM Rio Hondo 1, San Angel Tizapan Mexico City, MEXICO, 01000 Email: alfredo@itam.mx Sebastian

  1. MIRO: MIDDLEWARE FOR CONTROLLING BIOLOGICALLY INSPIRED MOBILE ROBOTS

    E-Print Network [OSTI]

    Weitzenfeld, Alfredo

    M�XICO rodrigo@cannes.itam.mx Alfredo Weitzenfeld Department of Computer Engineering Instituto Tecnológico Autónomo de México Río Hondo # 1, Tizapán San Ángel México, D. F., 01000 M�XICO alfredo@itam

  2. Biology and chemical control of the spotted alfalfa aphid 

    E-Print Network [OSTI]

    Downing, Douglas Holland

    1959-01-01T23:59:59.000Z

    , . 'ParathieO. , er sjstbyL. yaratbioe also sore'r'ended der', osa '-, ac tha'r'aca ef . ;l$ posed of, Social'tesfoaat yar: aero for . -', : -' , "" elecy'iito ointrol of, the. ipbid. , ; %ha as&de ievel rajl'in-. . hiiicRing' thebo -ioss@tioidas: se4...:. &rgea&ov'r &Lf, ~~?~. az. act~ 8&n ~), La . wgaet and coat' aboindiint ef 'erat', e dolmen'. Shit of:-". . . . ';"::. , '', ; " d~geedicij hCeer 'fLLaa fd~4 'Xn CalifdrnLIL. : The aadelta'-:, ". :u de ndc iat . aphidi;, b~t . gead 'on -ydllen, neater...

  3. Biological control of Rhizoctonia solani in greenhouse bedding plant production

    E-Print Network [OSTI]

    Brown, John Michael

    1983-01-01T23:59:59.000Z

    reduced damping-off of Celosia plumosa cv. Red Kewpie seedlings caused by R. solani. An uninoculated wheatbran preparation increased disease incidence. Incorpor ation of a lignite stillage inoculum preparations of Gliocladium spp. and T. harzianum... during the first ten days after sowing 27 Comparison of the wheat bran and lignite-sti llage carriers with biocontrols at the 3XRhizoctonia solani level 33 Comparison of treatment means at a R. solani level of 3X. The figure indicates no significant...

  4. Hydrologic Flow Controls on Biologic Iron(III) Reduction in

    E-Print Network [OSTI]

    Burgos, William

    for energy that likely increased cell synthesis, and decreased the concentration of sorbed Fe(II) that) in a goethite-coated sand was bioreduced by the DMRB Shewanella putrefaciens CN32 in a flow-through column

  5. Development of Foamed Emulsion Bioreactor for Air Pollution Control

    E-Print Network [OSTI]

    Development of Foamed Emulsion Bioreactor for Air Pollution Control Eunsung Kan, Marc A. Deshusses used bioreactors for air pollution control. © 2003 Wiley Periodicals, Inc. Biotechnol Bioeng 84: 240­244, 2003. Keywords: VOC control; biofilter; air pollution control; toluene; biologically activated foam

  6. Bridging gaps in synthetic biology oversight : iGEM as a testbed for proactive, adaptive risk management

    E-Print Network [OSTI]

    McNamara, Julie H. (Julie Hutton)

    2014-01-01T23:59:59.000Z

    On the surface, the emerging field of synthetic biology looks highly similar to that of genetic engineering. However, the two fields are based upon divergent underlying logic structures. Whereas genetic engineering affects ...

  7. Chemical and Biological Engineering Department Code 1 Department of Chemical & Biological Engineering

    E-Print Network [OSTI]

    Chemical and Biological Engineering Department Code 1 CODE of the Department of Chemical of Chemical & Biological Engineering. For clarity of presentation, some passages are copied directly from shall offer an undergraduate chemical and biological engineering program of technological, scientific

  8. A bioinformatics/computational biology postdoctoral research position available to analyze biological networks in plants

    E-Print Network [OSTI]

    Lu, Jiaheng

    A bioinformatics/computational biology postdoctoral research position available to analyze biological networks in plants A bioinformatics postdoctoral position is available immediately in the laboratory of Dr. Sue Rhee at the Carnegie Institution, Department of Plant Biology (Stanford, CA

  9. Microrobotic Simulator for Assisted Biological Cell Hamid Ladjal, Jean-Luc Hanus, Antoine Ferreira

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    , modeling, real-time interaction, haptic feedback. 1. INTRODUCTION Cell manipulation is a prevalent process to provide more controllable manipulation of biological cells [23], [24]. If visual servoing is a necessary and improve its control by developing a gesture similar to that performed in reality. In order to minimize

  10. Theoretical Physics in Cellular Biology

    E-Print Network [OSTI]

    Theoretical Physics in Cellular Biology: Some Illustrative Case Studies Living matter obeys the laws of physics, and the principles and methods of theoretical physics ought to find useful application observation, I will describe a few specific instances where approaches inspired by theoretical physics allow

  11. DEGREE REQUIREMENTS BIOLOGICAL ENGINEERING TECHNOLOGY

    E-Print Network [OSTI]

    Walter, M.Todd

    DEGREE REQUIREMENTS BIOLOGICAL ENGINEERING TECHNOLOGY ENVIRONMENTAL ENGINEERING TECHNOLOGY The curriculum in the technology programs must satisfy the College of Agriculture and Life Sciences (CALS for the technology programs are listed by subject matter in three major categories: (A) Basic Subjects, (B) Advanced

  12. WithCarbonSequestration Biological-

    E-Print Network [OSTI]

    · Techno-Economic Analysis of H2 Production by Gasification of Biomass · Renewables Analysis · BiomassWithCarbonSequestration Biomass Hydro Wind Solar Coal Nuclear Natural Gas Oil Biological- and Biomass- Based Hydrogen Production RoxanneRoxanne DanzDanz #12;Barriers Hydrogen Production from Biomass

  13. Biological Impacts of Climate Change

    E-Print Network [OSTI]

    McCarty, John P.

    Biological Impacts of Climate Change John P McCarty, University of Nebraska at Omaha, Omaha, NE and reproduction depend on how well adapted individuals are to local climate patterns. Climate change can disrupt subsequent impacts on populations or species' distributions across geographic regions. Climate change may

  14. Theory in Biology available light

    E-Print Network [OSTI]

    Nowak, Martin A.

    Magazine R406 Theory in Biology Theory is available light Martin A. Nowak Many people praise Gregor the neutral theory of evolution, which assumes that the overwhelming majority of molecular mutations do assume the neutral theory is correct. In a brilliant PhD thesis submitted in 1964, Bill Hamilton

  15. Transport-controlled kinetics of dissolution and precipitation...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Transport-controlled kinetics of dissolution and precipitation in the sediments under alkaline and saline conditions . Transport-controlled kinetics of dissolution and...

  16. Dream controller

    DOE Patents [OSTI]

    Cheng, George Shu-Xing; Mulkey, Steven L; Wang, Qiang; Chow, Andrew J

    2013-11-26T23:59:59.000Z

    A method and apparatus for intelligently controlling continuous process variables. A Dream Controller comprises an Intelligent Engine mechanism and a number of Model-Free Adaptive (MFA) controllers, each of which is suitable to control a process with specific behaviors. The Intelligent Engine can automatically select the appropriate MFA controller and its parameters so that the Dream Controller can be easily used by people with limited control experience and those who do not have the time to commission, tune, and maintain automatic controllers.

  17. Nuclear reactor control

    SciTech Connect (OSTI)

    Ingham, R.V.

    1980-01-01T23:59:59.000Z

    A liquid metal cooled fast breeder nuclear reactor has power setback means for use in an emergency. On initiation of a trip-signal a control rod is injected into the core in two stages, firstly, by free fall to effect an immediate power-set back to a safe level and, secondly, by controlled insertion. Total shut-down of the reactor under all emergencies is avoided. 4 claims.

  18. Environment induced incoherent controllability

    E-Print Network [OSTI]

    Raffaele Romano; Domenico D'Alessandro

    2005-11-08T23:59:59.000Z

    We prove that the environment induced entanglement between two non interacting, two-dimensional quantum systems S and P can be used to control the dynamics of S by means of the initial state of P. Using a simple, exactly solvable model, we show that both accessibility and controllability of S can be achieved under suitable conditions on the interaction of S and P with the environment.

  19. Department of Biology -Committees and Representatives

    E-Print Network [OSTI]

    Simons Biology Safety Committee Dave Omond Ed Bruggink Jim Cheetham (Chair) Mike Weber Biology Space Committee Jim Cheetham (Chair) Mike Weber Tom Sherratt Ed Bruggink Curriculum Committee (elected) Tom

  20. Stochastic processes in biological systems : selected problems

    E-Print Network [OSTI]

    Artomov, Maksym

    2010-01-01T23:59:59.000Z

    Majority of biological processes can not be described deterministically. Multple levels of regulation contribute to the noise in the observable properties of the cells: fluctuations are ubiquitous in biological networks ...

  1. Foundational platform for mammalian synthetic biology

    E-Print Network [OSTI]

    Davidsohn, Noah (Noah Justin)

    2013-01-01T23:59:59.000Z

    The emergent field of synthetic biology is different from many other biological engineering efforts, in that its roots, design principles, and forward engineering perspective have been adopted from electrical engineering ...

  2. Abiotic and Biological Transformation of Tetraalkoxysilanes

    E-Print Network [OSTI]

    Semprini, Lewis

    . An aerobic microbial culture from the local wastewater treatment plant that could grow and mineralizeAbiotic and Biological Transformation of Tetraalkoxysilanes and Trichloroethene/ cis-1 compounds (tetra- alkoxysilanes) by abiotic hydrolysis and biological mineralization was investigated

  3. Noah A. Rosenberg Department of Biology

    E-Print Network [OSTI]

    Rosenberg, Noah

    , Life Sciences Institute and Center for Computational Medicine & Bioinformatics, University of Michigan Education 2001-2005 University of Southern California, Postdoc, Molecular and Computational Biology 1998, BMC Bioinformatics 2010- Editorial Board Member, Human Biology 2010- Associate Editor, Genetics 2009

  4. Plating under reduced pressure

    SciTech Connect (OSTI)

    Dini, J.W.; Beat, T.G.; Cowden, W.C. (Lawrence Livermore National Lab., CA (United States)); Ryan, L.E.; Hewitt, W.B. (TRW, Inc., Redondo Beach, CA (United States))

    1992-06-01T23:59:59.000Z

    Plating under reduced pressure was evaluated for both electroless nickel and electrodeposited copper systems. The objective was to reduce pitting of these coatings thereby further enhancing their usage for diamond turning applications. Cursory experiments with electroless nickel showed reduced porosity when deposition was done at around 500 torr. Detailed experiments with electrodeposited copper at around 100 torr provided similar results. Scanning tunneling microscopy was effectively used to show the improvement in the copper deposits plated under reduced pressure. Benefits included reduced surface roughness and finer and denser grain structure.

  5. Biological and Synthetic Locomotion in Newtonian and Complex Fluids at Low Reynolds Number

    E-Print Network [OSTI]

    Pak, On Shun

    Fischer. Controlled propulsion of artificial magnetic nanos-of the magnetic field leads to propulsion in the oppositepredict the propulsion speed under different magnetic field

  6. Autonomous observations of the ocean biological carbon pump

    E-Print Network [OSTI]

    Bishop, James K.B.

    2009-01-01T23:59:59.000Z

    efficiency of biological pump in the global ocean. JournalOcean Biological Carbon Pump Carbon Flux Explorerocean’s “biological carbon pump” (Broecker and Peng, 1982;

  7. advanced molecular biology: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    311 Biology and Medicine Websites Summary: Molecular Biology Biology 311 Fall 2013 Syllabus Instructor: Dr. Deborah Lycan Class: MWF 9@lclark.edu Website: http:...

  8. PG&E Reconductoring Project Biological Assessment (Revised) ...

    Broader source: Energy.gov (indexed) [DOE]

    PG&E Reconductoring Project Biological Assessment (Revised) PG&E Reconductoring Project Biological Assessment (Revised) PG&E Reconductoring Project Biological Assessment (1216...

  9. EMSL Biological Interactions and Dynamics Science Theme Advisory...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biological Interactions and Dynamics Science Theme Advisory Panel Workshop EMSL Biological Interactions and Dynamics Science Theme Advisory Panel Workshop "Biological Interactions...

  10. Biology and distribution of the histerid beetles associated with bovine feces in South Central Texas

    E-Print Network [OSTI]

    Summerlin, James William

    1980-01-01T23:59:59.000Z

    :ed with bark beetles in western yellow pine, was conducted by Struble (1930). Recent studies concerning the potential value of histerids as biological control agents have done much to add to the knowledge of their behavior and bring recognition...BIOLOGY AND OISTRIBUTIilN GF THE HISTERID BEETLES ASSOCIATEO WITH BOVINE FECES IN SOUTH CENTRAL TEXAS A Thesis JAMES WILLIAM SUMMERLIN Submitted to the Graduate College of Texas ABm University in partial fulfillment of the requirement...

  11. Biological Inventory Colorado Canyons National Conservation Area

    E-Print Network [OSTI]

    Biological Inventory of the Colorado Canyons National Conservation Area Prepared by: Joe Stevens .............................. 12 Identify Targeted Inventory Areas

  12. A Biological Inventory and Conservation Recommendations

    E-Print Network [OSTI]

    A Biological Inventory and Conservation Recommendations for the Great Sand Dunes and San Luis Lakes General Services Building Ft. Collins, Colorado 80523 March 1999 i #12;A Biological Inventory PROGRAM SAGUACHE, COLORADO P.O. Box 674, Saguache, Colorado 81149 ii #12;Biological Inventory of the Great

  13. Graduate Programs in Plant Biology and

    E-Print Network [OSTI]

    Wildermuth, Mary C

    not re- biochemistry, cell and molecular biology (B22). pmb.berkeley.edu Plant&Microbial Biology #12;The to the environment will continue to fuel the expansion of plant research well into the future. The plant biology program focuses on contemporary ba- sic plant research, design of biotechnologies, and plant-microbe

  14. School of Environmental and Biological Sciences

    E-Print Network [OSTI]

    Goodman, Robert M.

    School of Environmental and Biological Sciences #12;Who We are and What We do Students at the Rutgers School of Environmental and Biological Sciences are part of a rich history of learning, innovation) Biological Sciences Biotechnology Animal Biotechnology Bioinformatics Bioscience Policy and Management

  15. Applications to Computational Molecular Biology Giuseppe Lancia

    E-Print Network [OSTI]

    Lancia, Giuseppe

    of the first type Bioinformatics problems, and reserve the term Computational Biology for the study of problemsApplications to Computational Molecular Biology Giuseppe Lancia 1 Introduction Computational decade. The seeds for the birth of Computational Biology were sowed in the end of the Seventies, when

  16. Undergraduate Minor in Computational biology & bioinformatics

    E-Print Network [OSTI]

    Logan, David

    Undergraduate Minor in Computational biology & bioinformatics Course Title Hours CSCE 155T Intro@unl.edu The Computational Biology and Bioinformatics (CBB) Minor is an interdisciplinary program that prepares students and for related graduate studies. The Computational Biology & Bioinformatics (CBB) Minor requires 13 credit hours

  17. Bioinformatics and Computational Biology Services Introduction

    E-Print Network [OSTI]

    Steiner, Ullrich

    Bioinformatics and Computational Biology Services Introduction Jenny Barna, Department of the Biological Sciences bioinformatics and computational biology research support service, which is used it provides. There are servers with many cores and very large memory (RAM) on which you can run computing jobs

  18. Optimization Under Generalized Uncertainty

    E-Print Network [OSTI]

    Lodwick, Weldon

    11 Optimization Under Generalized Uncertainty Optimization Modeling Math 4794/5794: Spring 2013 Weldon A. Lodwick Weldon.Lodwick@ucdenver.edu 2/14/2013 Optimization Modeling - Spring 2013 #12 in the context of optimization problems. The theoretical frame-work for these notes is interval analysis. From

  19. Roadmap: Biology Organismal Biology Bachelor of Science [AS-BS-BSCI-ORBI

    E-Print Network [OSTI]

    Sheridan, Scott

    Roadmap: Biology ­ Organismal Biology ­ Bachelor of Science [AS-BS-BSCI-ORBI] College of Arts/LNHD This roadmap is a recommended semester-by-semester plan of study for this major. However, courses General Elective 3 #12;Roadmap: Biology ­ Organismal Biology ­ Bachelor of Science [AS

  20. ECOLOGY, EVOLUTION AND ENVIRONMENTAL BIOLOGY (for students entering Biology in Fall 2011 or later)

    E-Print Network [OSTI]

    Jiang, Wen

    ECOLOGY, EVOLUTION AND ENVIRONMENTAL BIOLOGY (for students entering Biology in Fall 2011 or later course other than BIOL 54200 124 Total Credits BIOLOGY: 1. BIOL 12100 Biology I: Diversity, Ecology 28600 Intro. to Ecology and Evolution (2 cr.; spring) or BIOL 29500, Intro. to Evolution & Ecology (2 cr

  1. BIOINFORMATICS AND COMPUTATIONAL BIOLOGY 2014 Molecular Biology Building, Iowa State University, Ames, Iowa 50011-3260

    E-Print Network [OSTI]

    Mayfield, John

    BIOINFORMATICS AND COMPUTATIONAL BIOLOGY 2014 Molecular Biology Building, Iowa State University of recommendation in my file at the Bioinformatics and Computational Biology program, Iowa State University. [ ] I in the Bioinformatics and Computational Biology program at Iowa State University. We would appreciate your evaluation

  2. Louisiana Hazardous Waste Control Law (Louisiana)

    Broader source: Energy.gov [DOE]

    The Louisiana Department of Environmental Quality is responsible for administering the Louisiana Hazardous Waste Control Law and the regulations created under that law.

  3. An Algebraic Semantics of Prolog Control 

    E-Print Network [OSTI]

    Ross, Brian James

    , sequential Prolog's depth-first-left-first control is an unfair strategy under which nontermination can easily arise if programs are ill-structured. Formal analyses of logic programs therefore require an explicit formalisation of the control scheme...

  4. Distributed Generation Dispatch Optimization under Various Electricity Tariffs

    E-Print Network [OSTI]

    Firestone, Ryan; Marnay, Chris

    2007-01-01T23:59:59.000Z

    control strategies (load-follow, no-DG, and heat-follow),are nearly identical to the load-follow results; i.e. , theare lower than under either load-follow or no-DG, suggesting

  5. Biology Division. Progress report, August 1, 1982-September 30, 1983

    SciTech Connect (OSTI)

    Not Available

    1984-01-01T23:59:59.000Z

    The Biology Division is the component of the Oak Ridge National Laboratory that investigates the potential adverse health effects of energy-related substances. The body of this report provides summaries of the aims, scope and progress of the research of groups of investigators in the Division during the period of August 1, 1982, through September 30, 1983. At the end of each summary is a list of publications covering the same period (published or accepted for publication). For convenience, the summaries are assembled under Sections in accordance with the current organizational structure of the Biology Division; each Section begins with an overview. It will be apparent, however, that currents run throughout the Division and that the various programs support and interact with each other.

  6. AGRICULTURAL AND BIOLOGICAL ENGINEERING PURSUE A GRADUATE DEGREE IN

    E-Print Network [OSTI]

    Gilbert, Matthew

    AGRICULTURAL AND BIOLOGICAL ENGINEERING PURSUE A GRADUATE DEGREE IN AGRICULTURAL AND BIOLOGICAL ENGINEERING Department of Agricultural and Biological Engineering 338 Agricultural Engineering Sciences of Agricultural and Biological Engineering offers a limited number of graduate fellowships and assistantships

  7. Ecology and Evolutionary Biology The Wiess School of Natural Sciences

    E-Print Network [OSTI]

    Richards-Kortum, Rebecca

    Ecology and Evolutionary Biology The Wiess School of Natural Sciences Chair Evan Siemann Professors of Ecology and Evolutionary Biologyoffersabroadrangeofcoursesinthebiosciences:animalbehavior,animal biology, bioinformatics, conservation biology, diseases, ecology, evolutionary biology, field ecology, genetics, genomics

  8. Iosif Vaisman Department of Bioinformatics and Computational Biology

    E-Print Network [OSTI]

    Vaisman, Iosif

    Iosif Vaisman Department of Bioinformatics and Computational Biology Email: ivaisman@gmu.edu BINF agreed on the following definitions of bioinformatics and computational biology recognizing STRUCTURAL BIOLOGY COMPUTATIONAL MOLECULAR BIOLOGY BIOINFORMATICS GENOMICS STRUCTURAL GENOMICS PROTEOMICS

  9. Underground and under scrutiny

    E-Print Network [OSTI]

    Lee, Leslie

    2014-01-01T23:59:59.000Z

    2 txH2O Summer 2014 Story by Leslie Lee The Frio River, located in the Texas Hill Country, is spring-fed and therefore affected by groundwater pumping. Photo from istock.com. Underground and under scrutiny A changing state increasingly... their geological features is more multifaceted. Consider that each aquifer in Texas has different geological and hydrological character- istics, and therefore varying recharge rates, water quality and regional needs, and the complexity heightens. From a legal...

  10. Method of measurement in biological systems

    DOE Patents [OSTI]

    Turteltaub, K.W.; Vogel, J.S.; Felton, J.S.; Gledhill, B.L.: Davis, J.C.; Stanker, L.H.

    1993-05-11T23:59:59.000Z

    A method is disclosed of quantifying molecules in biological substances, comprising: selecting a biological host in which radioisotopes are present in concentrations equal to or less than those in the ambient biosphere; preparing a long-lived radioisotope labeled reactive chemical specie; administering the chemical specie to the biological host in doses sufficiently low to avoid significant overt damage to the biological system; allowing a period of time to elapse sufficient for dissemination and interaction of the chemical specie with the host throughout the biological system of the host; isolating a reacted fraction of the biological substance from the host in a manner sufficient to avoid contamination of the substance from extraneous sources; converting the fraction of biological substance by suitable means to a material which efficiently produces charged ions in at least one of several possible ion sources without introduction of significant isotopic fractionation; and measuring the radioisotope concentration in the material by means of direct isotopic counting.

  11. ADAPTIVE MODEL BASED CONTROL FOR WASTEWATER TREATMENT PLANTS

    E-Print Network [OSTI]

    Boucherie, Richard J.

    .j.boucherie@utwente.nl Abstract In biological wastewater treatment, nitrogen and phosphorous are removed by activated sludge in the Netherlands. An important step in the commonly applied biological wastewater treatment processADAPTIVE MODEL BASED CONTROL FOR WASTEWATER TREATMENT PLANTS Arie de Niet1 , Maartje van de Vrugt2

  12. Biological Engineering Electives Biosystems Engineering

    E-Print Network [OSTI]

    Hill, Jeffrey E.

    Control Theory (3) ECH 4323L Chemical Engineering Lab (1) ECH 4504 Chemical Kinetics & Reactor Design (4) ECH 4524 Heterogeneous Kinetics & Reactor Design (2) EGM 4313 Intermediate Engineering Analysis (4 Principles of Food Processing (4) FOS 4522C Seafood Technology (3) FOS 4722C Quality Control in Foods (3) FOS

  13. Auditory cortical neuron response dierences under isourane versus pentobarbital anesthesia

    E-Print Network [OSTI]

    Wang, Xiaoqin

    Auditory cortical neuron response di¡erences under iso£urane versus pentobarbital anesthesia Steven pentobarbital anesthesia in a within subject study control design. Initial microelectrode recordings were made under isoflurane anesthesia. After a several hour washout period, recordings were repeated at spatially

  14. Device Oriented Project Controller

    SciTech Connect (OSTI)

    Dalesio, Leo; Kraimer, Martin

    2013-11-20T23:59:59.000Z

    This proposal is directed at the issue of developing control systems for very large HEP projects. A de-facto standard in accelerator control is the Experimental Physics and Industrial Control System (EPICS), which has been applied successfully to many physics projects. EPICS is a channel based system that requires that each channel of each device be configured and controlled. In Phase I, the feasibility of a device oriented extension to the distributed channel database was demonstrated by prototyping a device aware version of an EPICS I/O controller that functions with the current version of the channel access communication protocol. Extensions have been made to the grammar to define the database. Only a multi-stage position controller with limit switches was developed in the demonstration, but the grammar should support a full range of functional record types. In phase II, a full set of record types will be developed to support all existing record types, a set of process control functions for closed loop control, and support for experimental beam line control. A tool to configure these records will be developed. A communication protocol will be developed or extensions will be made to Channel Access to support introspection of components of a device. Performance bench marks will be made on both communication protocol and the database. After these records and performance tests are under way, a second of the grammar will be undertaken.

  15. Biological production of ethanol from coal

    SciTech Connect (OSTI)

    Not Available

    1992-12-01T23:59:59.000Z

    Due to the abundant supply of coal in the United States, significant research efforts have occurred over the past 15 years concerning the conversion of coal to liquid fuels. Researchers at the University of Arkansas have concentrated on a biological approach to coal liquefaction, starting with coal-derived synthesis gas as the raw material. Synthesis gas, a mixture of CO, H[sub 2], CO[sub 2], CH[sub 4] and sulfur gases, is first produced using traditional gasification techniques. The CO, CO[sub 2] and H[sub 2] are then converted to ethanol using a bacterial culture of Clostridium 1jungdahlii. Ethanol is the desired product if the resultant product stream is to be used as a liquid fuel. However, under normal operating conditions, the wild strain'' produces acetate in favor of ethanol in conjunction with growth in a 20:1 molar ratio. Research was performed to determine the conditions necessary to maximize not only the ratio of ethanol to acetate, but also to maximize the concentration of ethanol resulting in the product stream.

  16. Engineering control of eukaryotic translation with application to the malaria parasite Plasmodium falciparum

    E-Print Network [OSTI]

    Goldfless, Stephen J. (Stephen Jacob)

    2014-01-01T23:59:59.000Z

    Experimenter control of target gene expression is a fundamental component of molecular biology research. In many systems, tools exist that allow generalizable control of gene expression at the transcriptional or ...

  17. First Passage Problems in Biology

    E-Print Network [OSTI]

    Tom Chou; Maria R. D'Orsogna

    2014-08-20T23:59:59.000Z

    Applications of first passage times in stochastic processes arise across a wide range of length and time scales in biological settings. After an initial technical overview, we survey representative applications and their corresponding models. Within models that are effectively Markovian, we discuss canonical examples of first passage problems spanning applications to molecular dissociation and self-assembly, molecular search, transcription and translation, neuronal spiking, cellular mutation and disease, and organismic evolution and population dynamics. In this last application, a simple model for stem-cell ageing is presented and some results derived. Various approximation methods and the physical and mathematical subtleties that arise in the chosen applications are also discussed.

  18. Systems biology of Microbial Communities

    SciTech Connect (OSTI)

    Navid, A; Ghim, C; Fenley, A; Yoon, S; Lee, S; Almaas, E

    2008-04-11T23:59:59.000Z

    Microbes exist naturally in a wide range of environments, spanning the extremes of high acidity and high temperature to soil and the ocean, in communities where their interactions are significant. We present a practical discussion of three different approaches for modeling microbial communities: rate equations, individual-based modeling, and population dynamics. We illustrate the approaches with detailed examples. Each approach is best fit to different levels of system representation, and they have different needs for detailed biological input. Thus, this set of approaches is able to address the operation and function of microbial communities on a wide range of organizational levels.

  19. Biological Safety | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't Your Destiny: The FutureCommentsEnergyandapproximately 10 wt%inand FuelBiological

  20. Computational Biology | More Science | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville Power Administration would like submit theInnovationComputational Biology SHARE Computational

  1. Systems Biology | More Science | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What'sis Taking Over Our InstagramStructureProposed Action(InsertAbout the GeothermalSystems Biology

  2. Green Biologics | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are8COaBulkTransmissionSitingProcess.pdfGetec AG Contracting JumpGoveNebraska:Ethanol LLC GO EthanolBiologics Jump to:

  3. Biological Applications of Synchrotron Radiation:

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625govInstrumentstdmadapInactiveVisiting the TWP TWPAlumniComplexMaterialProduction PetraBiological

  4. Biology of Cancer Stefan Bentink September 2002 Biology of Cancer

    E-Print Network [OSTI]

    Spang, Rainer

    are normaly responsible for negative controll of transcription and proliferation Examples: pRb inhibits Bentink September 2002 Tumor suppressor genes: rb pRb E2F pRb E2F E

  5. apu controller removal: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    contamination control 12;10 Transfer of Graphite to Supersack (V) 12;11 Moving graphite pile Complete shipment of graphite to DOE's Nevada Test Site Removal of biological shield...

  6. Multiphase flow and control of fluid path in microsystems

    E-Print Network [OSTI]

    Jhunjhunwala, Manish

    2005-01-01T23:59:59.000Z

    Miniaturized chemical-systems are expected to have advantages of handling, portability, cost, speed, reproducibility and safety. Control of fluid path in small channels between processes in a chemical/biological network ...

  7. Neuromechanics: an integrative approach for understanding motor control

    E-Print Network [OSTI]

    Daniel, Tom

    Neuromechanics: an integrative approach for understanding motor control Kiisa Nishikawa,1,Ã Andrew of Biology, University of North Carolina, Wilmington, NC 28409, USA Synopsis Neuromechanics seeks of neuromechanics include ameliorating human health problems (including prosthesis design and restoration

  8. Mineralogy under extreme conditions

    SciTech Connect (OSTI)

    Shu, Jinfu (CIW)

    2012-02-07T23:59:59.000Z

    We have performed measurements of minerals based on the synchrotron source for single crystal and powder X-ray diffraction, inelastic scattering, spectroscopy and radiography by using diamond anvil cells. We investigated the properties of iron (Fe), iron-magnesium oxides (Fe, Mg)O, silica(SiO{sub 2}), iron-magnesium silicates (Fe, Mg)SiO{sub 3} under simulated high pressure-high temperature extreme conditions of the Earth's crust, upper mantle, low mantle, core-mantle boundary, outer core, and inner core. The results provide a new window on the investigation of the mineral properties at Earth's conditions.

  9. Optimal control of interbank contagion under complete information

    E-Print Network [OSTI]

    infusions. This problem is motivated by the government interventions during the recent crisis, which took and the gain from these equity infusion programs is an important topic of notable research in the finance), Bayazitova and Shivdasani (2012), Philippon and Schnabl (2009). Several possible reasons for equity infusion

  10. Vehicle Level Model and Control Development and Validation Under...

    Broader source: Energy.gov (indexed) [DOE]

    Division * NREL Relevance Temperature Has a Significant Impact on Electric Drive Energy Consumption 3 Vehicle Dynamometer Testing Source: ANL APRF - 2013 Ford Cmax Energi Fleet...

  11. Bringing the Low NOx Diesel Under Control | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't Your Destiny: Theof Energy Future of CSP: ChallengesEnergy ForEnergy Bringing

  12. Performance of Networked Control Systems under Sporadic Feedback

    E-Print Network [OSTI]

    Lemmon, Michael

    Regenerative Braking power inverter storage Micro-Grid Renewable Generation PHEV Smart Grid - Distributed

  13. Signal processing underlying extrinsic control of stem cell fate

    E-Print Network [OSTI]

    Zandstra, Peter W.

    orchestrate the generation, maintenance, and re- generation of tissue while suppressing aberrant growth flexible to address these multifaceted and typi- cally exogenously elicited responses. Although numer- ous

  14. Electric Drive Vehicle Level Control Development Under Various Thermal

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't Your Destiny:RevisedAdvisory BoardNucleate Boiling Efficient CoolingInc. || DepartmentConditions

  15. Radionuclides in biology and medicine-review and future

    SciTech Connect (OSTI)

    Cameron, J.R. [Cameron Consultant, Lone Rock, WI (United States)

    1996-12-31T23:59:59.000Z

    Radioactivity was discovered by Becquerel in France on March 1, 1896. It is appropriate in this centennial year to review its history, especially its applications in biology and medicine. Its future is currently {open_quotes}under a cloud{close_quotes} because of the exaggerated fear of health risks from low-level radioactivity. The author is optimistic about its future, but one will have to wait a few decades for the cloud of ignorance to pass and the sunshine of education about radiation to greatly reduce radiation phobia.

  16. Rapid classification of biological components

    DOE Patents [OSTI]

    Thompson, Vicki S. (Idaho Falls, ID); Barrett, Karen B. (Meridian, ID); Key, Diane E. (Idaho Falls, ID)

    2010-03-23T23:59:59.000Z

    A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, cocaine (crystalline tropane alkaloid), methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens to a surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do not form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to a subject's identity.

  17. Rapid classification of biological components

    DOE Patents [OSTI]

    Thompson, Vicki S.; Barrett, Karen B.; Key, Diane E.

    2006-01-24T23:59:59.000Z

    A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, cocaine, methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens to the surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to the subject's identity.

  18. Rapid classification of biological components

    DOE Patents [OSTI]

    Thompson, Vicki S. (Idaho Falls, ID); Barrett, Karen B. (Meridian, ID); Key, Diane E. (Idaho Falls, ID)

    2010-03-23T23:59:59.000Z

    A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, Cocaine (crystalline tropane alkaloid), methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens of the surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do not form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to a subject's identity.

  19. A Comprehensive Collection of Systems Biology Data Characterizing the Host Response to Viral Infection

    SciTech Connect (OSTI)

    Aevermann, Brian; Pickett, Brett E.; Kumar, Sanjeev; Klem, Edward B.; Agnihothram, Sudhakar; Askovich, Peter S.; Bankhead, Armand; Bolles, Meagan; Carter, Victoria; Chang, Jean H.; Clauss, Therese RW; Dash, Pradyot; Diercks, Alan H.; Eisfeld, Amie J.; Ellis, Amy L.; Fan, Shufang; Ferris, Martin T.; Gralinski, Lisa; Green, Richard; Gritsenko, Marina A.; Hatta, Masato; Heegel, Robert A.; Jacobs, Jon M.; Jeng, Sophia; Josset, Laurence; Kaiser, Shari M.; Kelly, Sarah; Law, Gale L.; Li, Chengjun; Li, Jiangning; Long, Casey; Luna, Maria L.; Matzke, Melissa M.; McDermott, Jason E.; Menachery, Vineet; Metz, Thomas O.; Mitchell, Hugh D.; Monroe, Matthew E.; Navarro, Garnet; Neumann, Gabriele; Podyminogin, Rebecca L.; Purvine, Samuel O.; Rosenberger, Carrie; Sanders, Catherine J.; Schepmoes, Athena A.; Shukla, Anil K.; Sims, Amy; Sova, Pavel; Tam, Vincent C.; Tchitchek, Nicholas; Thomas, Paul G.; Tilton, Susan C.; Totura, Allison L.; Wang, Jing; Webb-Robertson, Bobbie-Jo M.; Wen, Ji; Weiss, Jeffrey M.; Yang, Feng; Yount, Boyd; Zhang, Qibin; Mcweeney, Shannon K.; Smith, Richard D.; Waters, Katrina M.; Kawaoka, Yoshihiro; Baric, Ralph; Aderem, Alan; Katze, Michael G.; Scheuermann, Richard H.

    2014-10-14T23:59:59.000Z

    The Systems Biology for Infectious Diseases Research program was established by the U.S. National Institute of Allergy and Infectious Diseases to investigate host-pathogen interactions at a systems level. This program generated 47 transcriptomic and proteomic datasets from 30 studies that investigate in vivo and in vitro host responses to viral infections. Human pathogens in the Orthomyxoviridae and Coronaviridae families, especially pandemic H1N1 and avian H5N1 influenza A viruses and severe acute respiratory syndrome coronavirus (SARS-CoV), were investigated. Study validation was demonstrated via experimental quality control measures and meta-analysis of independent experiments performed under similar conditions. Primary assay results are archived at the GEO and PeptideAtlas public repositories, while processed statistical results together with standardized metadata are publically available at the Influenza Research Database (www.fludb.org) and the Virus Pathogen Resource (www.viprbrc.org). By comparing data from mutant versus wild-type virus and host strains, RNA versus protein differential expression, and infection with genetically similar strains, these data can be used to further investigate genetic and physiological determinants of host responses to viral infection.

  20. Electrostatic thin film chemical and biological sensor

    DOE Patents [OSTI]

    Prelas, Mark A. (Columbia, MO); Ghosh, Tushar K. (Columbia, MO); Tompson, Jr., Robert V. (Columbia, MO); Viswanath, Dabir (Columbia, MO); Loyalka, Sudarshan K. (Columbia, MO)

    2010-01-19T23:59:59.000Z

    A chemical and biological agent sensor includes an electrostatic thin film supported by a substrate. The film includes an electrostatic charged surface to attract predetermined biological and chemical agents of interest. A charge collector associated with said electrostatic thin film collects charge associated with surface defects in the electrostatic film induced by the predetermined biological and chemical agents of interest. A preferred sensing system includes a charge based deep level transient spectroscopy system to read out charges from the film and match responses to data sets regarding the agents of interest. A method for sensing biological and chemical agents includes providing a thin sensing film having a predetermined electrostatic charge. The film is exposed to an environment suspected of containing the biological and chemical agents. Quantum surface effects on the film are measured. Biological and/or chemical agents can be detected, identified and quantified based on the measured quantum surface effects.

  1. Functional quantum biology in photosynthesis and magnetoreception

    E-Print Network [OSTI]

    Lambert, Neill; Cheng, Yuan-Chung; Li, Che-Ming; Chen, Guang-Yin; Nori, Franco

    2012-01-01T23:59:59.000Z

    Is there a functional role for quantum mechanics or coherent quantum effects in biological processes? While this question is as old as quantum theory, only recently have measurements on biological systems on ultra-fast time-scales shed light on a possible answer. In this review we give an overview of the two main candidates for biological systems which may harness such functional quantum effects: photosynthesis and magnetoreception. We discuss some of the latest evidence both for and against room temperature quantum coherence, and consider whether there is truly a functional role for coherence in these biological mechanisms. Finally, we give a brief overview of some more speculative examples of functional quantum biology including the sense of smell, long-range quantum tunneling in proteins, biological photoreceptors, and the flow of ions across a cell membrane.

  2. Functional quantum biology in photosynthesis and magnetoreception

    E-Print Network [OSTI]

    Neill Lambert; Yueh-Nan Chen; Yuan-Chung Cheng; Che-Ming Li; Guang-Yin Chen; Franco Nori

    2012-05-04T23:59:59.000Z

    Is there a functional role for quantum mechanics or coherent quantum effects in biological processes? While this question is as old as quantum theory, only recently have measurements on biological systems on ultra-fast time-scales shed light on a possible answer. In this review we give an overview of the two main candidates for biological systems which may harness such functional quantum effects: photosynthesis and magnetoreception. We discuss some of the latest evidence both for and against room temperature quantum coherence, and consider whether there is truly a functional role for coherence in these biological mechanisms. Finally, we give a brief overview of some more speculative examples of functional quantum biology including the sense of smell, long-range quantum tunneling in proteins, biological photoreceptors, and the flow of ions across a cell membrane.

  3. On Biology as an Emergent Science

    E-Print Network [OSTI]

    H. Pierre Noyes

    2007-05-31T23:59:59.000Z

    Biology is considered here as an "emergent science" in the sense of Anderson and of Laughlin and Pines. It is demonstrated that a straightforward mathematical definition of "biological system" is useful in showing how biology differs in structure from the lower levels in Anderson's "More is Different" hierarchy. Using cells in a chemostat as a paradigmatic exemplar of a biological system, it is found that a coherent collection of metabolic pathways through a single cell in the chemostat also satisfies the proposed definition of a biological system. This provides a theoretical and mathematical underpinning for Young's fundamental model of biological organization and integration. Evidence for the therapeutic efficacy of Young's method of analysis is provided by preliminary results of clinical trials of a specific application of Young's model to the treatment of cancer cachexia.

  4. Microprocessor–based monochromator controller

    E-Print Network [OSTI]

    Dalle-Molle, Richard; Defreese, James D.

    1980-04-01T23:59:59.000Z

    Microprocessor-based monochromator controller Richard Dalle-Molle and James D. Defreese* University of Kansas, Department of Chemistry, Lawrence, Kansas 66045, USA. Introduction The modular nature of the EU-700 series spectrometers (GCA... put under the control of another computer. The microprocessor was chosen in preference to other types of "hardware" controllers for a number of reasons; it is easier to implement, easier to modify the design and it is more adaptable to changing...

  5. Theory: Biological systems organize to maximize entropy production subject to information and biophysicochemical constraints.

    E-Print Network [OSTI]

    Vallino, Joseph J.

    Theory: Biological systems organize to maximize entropy production subject to information the fitness landscape is as dynamic as the organisms themselves. The theory of MEP under biophysicochemical, 2005b) presented a provisional proof on the theory of maximum entropy production (MEP), which posits

  6. Dynamics of a Multilocus Trait Center for the Study of Evolution, School of Biological Sciences,

    E-Print Network [OSTI]

    Waxman, David

    Dynamics of a Multilocus Trait D. WAXMAN Center for the Study of Evolution, School of Biological: 6 May 2000) A detailed theoretical study of the dynamical behaviour of a quantitative trait under the explicit dynamics. Numerical tests of dynamical results over 104 generations and equilibrium results

  7. On-line tools for sequence retrieval and multivariate statistics in molecular biology

    E-Print Network [OSTI]

    Thioulouse, Jean

    On-line tools for sequence retrieval and multivariate statistics in molecular biology Guy Perrière@biomserv.univ-lyon1.fr Keywords: World-Wide Web; Sequence data banks; Retrieval system; Multivariateanalysis; Sequence for browsing sequence collections structured under ACNUC format and for performing multivariate analyses

  8. BIOLOGICAL OPINION ON ISSUANCE OF INCIDENTAL HARASSMENT AUTHORIZATIONS FOR OIL AND GAS EXPLORATION ACTIVITIES IN THE CHUKCHI AND BEAUFORT SEAS IN 2010

    E-Print Network [OSTI]

    #12;BIOLOGICAL OPINION ON ISSUANCE OF INCIDENTAL HARASSMENT AUTHORIZATIONS FOR OIL AND GAS..............................................................................................................84 i #12;BIOLOGICAL OPINION ON ISSUANCE OF INCIDENTAL HARASSMENT AUTHORIZATIONS FOR OIL AND GAS" permits under section 101(a)(5) of the Marine Mammal Protection Act, as amended, for certain oil and gas

  9. Molecular biology of signal transduction in plants

    SciTech Connect (OSTI)

    Not Available

    1991-01-01T23:59:59.000Z

    This volume contains abstracts of oral presentations and poster sessions of the 1991 Cold Springs Harbor Meeting entitled Molecular Biology of Signal Transduction in Plants.

  10. Innovative Breakthrough Demonstrated for Biological Ethanol Production...

    Office of Environmental Management (EM)

    for Biological Ethanol Production June 30, 2015 - 11:43am Addthis Advanced Biofuels Process Demonstration Unit at Lawrence Berkeley National Laboratory. Photo credit:...

  11. Carbonic Acid Shows Promise in Geology, Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The Surprising Secrets of Carbonic Acid Probing the Surprising Secrets of Carbonic Acid Berkeley Lab Study Holds Implications for Geological and Biological Processes October 23,...

  12. Biological Survey of the Upper Purgatoire Watershed

    E-Print Network [OSTI]

    Biological Survey of the Upper Purgatoire Watershed Las Animas County, CO John Carney Colorado ...............................................................................................................9 Management Urgency Ranks ........................................................................................................10 POTENTIAL CONSERVATION SITE PLANNING BOUNDARIES........................................12 Off

  13. Calcite precipitation dominates the electrical signatures of zero valent iron columns under simulated field conditions

    E-Print Network [OSTI]

    Wu, Yuxin

    2009-01-01T23:59:59.000Z

    concentrations, i.e. calcium and carbonate controllingSolutions Containing Calcium Carbonate with Trichloroetheneand transformation of calcium carbonate polymorphs under

  14. Molecular motors: design, mechanism and control

    E-Print Network [OSTI]

    Debashish Chowdhury

    2008-01-10T23:59:59.000Z

    Biological functions in each animal cell depend on coordinated operations of a wide variety of molecular motors. Some of the these motors transport cargo to their respective destinations whereas some others are mobile workshops which synthesize macromolecules while moving on their tracks. Some other motors are designed to function as packers and movers. All these motors require input energy for performing their mechanical works and operate under conditions far from thermodynamic equilibrium. The typical size of these motors and the forces they generate are of the order of nano-meters and pico-Newtons, respectively. They are subjected to random bombardments by the molecules of the surrounding aqueous medium and, therefore, follow noisy trajectories. Because of their small inertia, their movements in the viscous intracellular space exhibits features that are characteristics of hydrodynamics at low Reynold's number. In this article we discuss how theoretical modeling and computer simulations of these machines by physicists are providing insight into their mechanisms which engineers can exploit to design and control artificial nano-motors.

  15. Division of Biological and Medical Research annual research summary, 1983

    SciTech Connect (OSTI)

    Barr, S.H. (ed.)

    1984-08-01T23:59:59.000Z

    This research summary contains brief descriptions of research in the following areas: (1) mechanisms of hepatocarcinogenesis; (2) role of metals in cocarcinogenesis and the use of liposomes for metal mobilization; (3) control of mutagenesis and cell differentiation in cultured cells by tumor promoters; (4) radiation effects in mammalian cells; (5) radiation carcinogenesis and radioprotectors; (6) life shortening, tumor induction, and tissue dose for fission-neutron and gamma-ray irradiations; (7) mammalian genetics and biostatistics; (8) radiation toxicity studies; (9) hematopoiesis in chronic toxicity; (10) molecular biology studies; (11) chemical toxicology; (12) carcinogen identification and metabolism; (13) metal metabolism and toxicity; and (14) neurobehavioral chronobiology. (ACR)

  16. Chemical and Biological Engineering Department of Chemical and Biological Engineering

    E-Print Network [OSTI]

    Heller, Barbara

    Fuel Cell Lab Fuel Cell Battery Lab Fluidization Lab Gas Processing Lab Interfacial Phenomena Lab Light's core areas of research competency: Energy and Sustainability Fuel Cells Fluidization and Gasification Polymer Reaction Engineering Lab Porous Media and Core Analysis Lab Process Control & Optimization Lab

  17. Plant Species Biology (2003) 18, 123127 2003 The Society for the Study of Species Biology

    E-Print Network [OSTI]

    Tomimatsu,, Hiroshi

    2003-01-01T23:59:59.000Z

    and Genetics, Graduate School of Environmental Earth Science, Hokkaido University, Sapporo 060-0810, JapanPlant Species Biology (2003) 18, 123­127 © 2003 The Society for the Study of Species Biology Blackwell Science, LtdOxford, UKPSBPlant Species Biology1442-1984The Society for the Study of Species

  18. Quality Control and Captive Rearing Genetics of the Biological Control Agent Trichogramma pretiosum

    E-Print Network [OSTI]

    Gonzalez-Cabrera, Jaime

    2011-01-01T23:59:59.000Z

    rain, presence of agrochemicals, parasitoid dispersion, orresidues of toxic agrochemicals, high parasitoid dispersion

  19. Quality Control and Captive Rearing Genetics of the Biological Control Agent Trichogramma pretiosum

    E-Print Network [OSTI]

    Gonzalez-Cabrera, Jaime

    2011-01-01T23:59:59.000Z

    M. Sgro, and A. A. Hoffmann. 2009. Fundamental evolutionaryBennett, D. M. , and A. A. Hoffmann. 1998. Effects of sizeWallingford, UK, pp. 89-92. Hoffmann, M. P. , P. R. Ode, D.

  20. Calibration Under Uncertainty.

    SciTech Connect (OSTI)

    Swiler, Laura Painton; Trucano, Timothy Guy

    2005-03-01T23:59:59.000Z

    This report is a white paper summarizing the literature and different approaches to the problem of calibrating computer model parameters in the face of model uncertainty. Model calibration is often formulated as finding the parameters that minimize the squared difference between the model-computed data (the predicted data) and the actual experimental data. This approach does not allow for explicit treatment of uncertainty or error in the model itself: the model is considered the %22true%22 deterministic representation of reality. While this approach does have utility, it is far from an accurate mathematical treatment of the true model calibration problem in which both the computed data and experimental data have error bars. This year, we examined methods to perform calibration accounting for the error in both the computer model and the data, as well as improving our understanding of its meaning for model predictability. We call this approach Calibration under Uncertainty (CUU). This talk presents our current thinking on CUU. We outline some current approaches in the literature, and discuss the Bayesian approach to CUU in detail.

  1. Knowledge-based control 

    E-Print Network [OSTI]

    Painter, John H.

    1992-03-17T23:59:59.000Z

    parts; comprising the eyetern (plant) under control, an inferential estima- tor, and a memoryless controller. 138 . - - Authorized licensed use limited to: Texas A M University. Downloaded on February 18,2010 at 14:24:05 EST from IEEE Xplore... modes are tems exhibiting a finite (or at least countable) num- ber of states, a theoretical basis parallel to that ex- 139 Authorized licensed use limited to: Texas A M University. Downloaded on February 18,2010 at 14:24:05 EST from IEEE Xplore...

  2. Project Controls

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1997-03-28T23:59:59.000Z

    Project controls are systems used to plan, schedule, budget, and measure the performance of a project/program. The cost estimation package is one of the documents that is used to establish the baseline for project controls. This chapter gives a brief description of project controls and the role the cost estimation package plays.

  3. Journal of Steroid Biochemistry & Molecular Biology 127 (2011) 915 Contents lists available at ScienceDirect

    E-Print Network [OSTI]

    Blumberg, Bruce

    -2300, United States b Department of Pharmaceutical Sciences, University of California, Irvine, CA, United energy balance to favor the storage of calories and by altering the hormonal control of appetite Biological Sciences 3, University of California, Irvine, CA 92697-2300, United States. Tel.: +1 949 824 8573

  4. Robotics in Crop Production Department of Agricultural and Biological Engineering, University of Illinois at

    E-Print Network [OSTI]

    Robotics in Crop Production Tony Grift Department of Agricultural and Biological Engineering such as harvesting of citrus fruits, grapes, and raisins. An important part of Automation is the use of robots. Robotics in agriculture is not a new concept; in controlled environments (green houses), it has a his- tory

  5. Max-Planck-Institut fr biologische Kybernetik Max Planck Institute for Biological Cybernetics

    E-Print Network [OSTI]

    and analysis of human psychophysical experiments. · Good understanding of the English language in speaking Position in Human Motion Simulation The Max Planck Institute for Biological Cybernetics in Tübingen laws of perception will be implemented into the control framework of motion-based simulators. Human

  6. nature biotechnology volume 27 number 12 december 2009 1127 Recent patent applications in synthetic biology

    E-Print Network [OSTI]

    Cai, Long

    for controlling cell function, as a raw material in synthetic biology for reconstructing a biomolecule relative to the expression in the first organism strain prior to its transformation. Advanced Biofuels element having a left inverted repeat region, a right inverted repeat region and a spacer region

  7. Real-time fault detection and isolation in biological wastewater treatment plants

    E-Print Network [OSTI]

    Real-time fault detection and isolation in biological wastewater treatment plants F. Baggiani and S@dsi.unifi.it Automatic fault detection is becoming increasingly important in wastewater treatment plant operation, given automation controllers, wastewater treatment INTRODUCTION Real-time monitoring is an increasingly important

  8. Biological Hydrogen Production Using a Membrane Bioreactor

    E-Print Network [OSTI]

    Biological Hydrogen Production Using a Membrane Bioreactor Sang-Eun Oh,1 Prabha Iyer,1,2 Mary Ann bioreactor (MBR) for biological hydrogen production. The reactor was fed glucose (10,000 mg/L) and inoculated were used. B 2004 Wiley Periodicals, Inc. Keywords: membrane bioreactor; hydrogen production

  9. Southeastern Colorado Survey of Critical Biological Resources

    E-Print Network [OSTI]

    Southeastern Colorado Survey of Critical Biological Resources 2007 #12;ii #12;Southeastern Colorado Survey of Critical Biological Resources Prepared for: Colorado Cattleman's Agricultural Land Trust 8833 Department of Natural Resources Division of State Board of Land Commissioners 1313 Sherman Street Denver, CO

  10. Ninth International Workshop on Plant Membrane Biology

    SciTech Connect (OSTI)

    Not Available

    1993-12-31T23:59:59.000Z

    This report is a compilation of abstracts from papers which were discussed at a workshop on plant membrane biology. Topics include: plasma membrane ATP-ases; plant-environment interactions, membrane receptors; signal transduction; ion channel physiology; biophysics and molecular biology; vaculor H+ pumps; sugar carriers; membrane transport; and cellular structure and function.

  11. Book Review Geothermal Biology and Geochemis-

    E-Print Network [OSTI]

    Book Review Geothermal Biology and Geochemis- try in Yellowstone National Park. (eds WP Inskeep of life. The legacy of chemical and biologi- cal research in geothermal regimes, while short in duration geothermal areas, including Yellowstone, are largely confined to the specialty literature of geochemical

  12. STOCHASTIC GENERATION OF BIOLOGICALLY ACCURATE BRAIN NETWORKS

    E-Print Network [OSTI]

    STOCHASTIC GENERATION OF BIOLOGICALLY ACCURATE BRAIN NETWORKS A Thesis by ARAVIND ALURI Submitted OF BIOLOGICALLY ACCURATE BRAIN NETWORKS A Thesis by ARAVIND ALURI Submitted to the Office of Graduate Studies Head of Department, Valerie Taylor December 2005 Major Subject: Computer Science #12;iii ABSTRACT

  13. Bi23 BIOLOGY TUTORIALS WINTER TERM 2014

    E-Print Network [OSTI]

    Low, Steven H.

    Bi23 BIOLOGY TUTORIALS WINTER TERM 2014 SECTIONS 1 ­ 3 The Function and Regulation of Sleep (3. Huang, x3446, MC 156-29 #12;Bi23 BIOLOGY TUTORIALS WINTER TERM 2014 SECTIONS 4-6 Physical Principles crystallography and neutron scattering; nuclear magnetic resonance and magnetic resonance imaging; peptide and DNA

  14. Genome Biology 2005, 6:312 commentreviewsreportsdepositedresearchinteractionsinformationrefereedresearch

    E-Print Network [OSTI]

    Kellis, Manolis

    Genome Biology 2005, 6:312 commentreviewsreportsdepositedresearchinteractionsinformationrefereedresearch Meeting report Large-scale discovery and validation of functional elements in the human genome-mail: bbernst@fas.harvard.edu. Manolis Kellis. E-mail: manoli@mit.edu Published: 1 March 2005 Genome Biology

  15. FINAL REPORT FOR: OPTIMIZATION OF BIOLOGICAL

    E-Print Network [OSTI]

    AND SUSPENDED GROWTH WASTEWATER TREATMENT SYSTEM DECEMBER, 1994 Prepared for: Environment Canada Environment#12;FINAL REPORT FOR: OPTIMIZATION OF BIOLOGICAL PHOSPHORUS AND AMMONIA REMOVAL IN A COMBINED FIXED;Optimization of Biological Phosphorus and Ammonia Removal in a Combined Fixed & Suspended Growth System i

  16. Waste Handling and Disposal Biological Safety

    E-Print Network [OSTI]

    Pawlowski, Wojtek

    plumbing services, EHS personnel wastewater treatment plant personnel, and the general public canWaste Handling and Disposal Biological Safety General Biosafety Practices (GBP) Why You Should Care on the next experiment. Are you working with r/sNA, biological toxins, human materials, needles, plasticware

  17. Bing Concert Hall, Under Construction

    E-Print Network [OSTI]

    Prinz, Friedrich B.

    BioE/ChemE Building Bing Concert Hall, Under Construction Arrillaga Family Dining Commons West Campus Recreation Center, Under Construction BioE/ChemE Building, Under Construction Terman Engineering Moore Materials Rsrch. Durand David Packard Elect. Eng. Paul G. Allen Building Roble Pool Roble Modulars

  18. 3, 805826, 2006 Ventilation under

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    OSD 3, 805­826, 2006 Ventilation under global warming A. Gnanadesikan et al. Title Page Abstract ocean ventilation change under global warming? A. Gnanadesikan 1 , J. L. Russell 2 , and F. Zeng 3 1­826, 2006 Ventilation under global warming A. Gnanadesikan et al. Title Page Abstract Introduction

  19. African Rue Biology and Management

    E-Print Network [OSTI]

    Hart, Charles R.

    2002-10-17T23:59:59.000Z

    African rue is a toxic and highly invasive plant found in western parts of Texas. This publication describes the plant and explains the symptoms it can cause in livestock that ingest it. There are suggestions for controlling African rue on rangeland...

  20. On linear programing approach to inventory control

    E-Print Network [OSTI]

    Mayfield, John

    On linear programing approach to inventory control problems Zhu received his PhD from Wayne State with inventory control problems under the discounted criterion. The objective is to minimize the discounted total imbeds the inventory control problem into an infinite-dimensional linear program over a space of measures

  1. JPRS report: Arms control, [December 11, 1991

    SciTech Connect (OSTI)

    NONE

    1991-12-11T23:59:59.000Z

    This document contains articles translated into English from foreign periodicals. They concern arms control throughout the world. Some topics discussed are strategic defense initiative, space arms, intermediate-range nuclear forces, conventional forces in Europe, short-range nuclear forces, nuclear testing, chemical and biological weapons, nuclear-free zones and peace zones, Asian security issues, and nuclear weapons issues.

  2. JPRS report: Arms control, [November 22, 1991

    SciTech Connect (OSTI)

    NONE

    1991-11-22T23:59:59.000Z

    This document contains articles translated from foreign periodicals into English that concern arms control throughout the world. Some topics discussed are nuclear testing, conventional forces in Europe, chemical and biological weapons, naval arms limitations, Asian security issues, nuclear weapons issues, and disarmament.

  3. Worldwide report: Arms control, [April 9, 1987

    SciTech Connect (OSTI)

    NONE

    1987-04-09T23:59:59.000Z

    This report contains information concerning arms control and the USSR. Topics include: (1) SDI and space arms, (2) US-USSR nuclear and space arms talks, (3) intermediate range nuclear forces, (4) chemical and biological weapons, (5) nuclear testing and free zone proposals, (6) related issues.

  4. Biological and Ecological Aspects of Field Released Fire Ant Decapitating Flies Pseudacteon spp. (Diptera: Phoridae), Parasitoids of Red Imported Fire Ants Solenopsis invicta Buren (Hymenoptera: Formicidae)

    E-Print Network [OSTI]

    Puckett, Robert T.

    2010-01-14T23:59:59.000Z

    Multiple Pseudacteon phorid fly species, including P. tricuspis and P. curvatus, have been released in the southern United States beginning in 1997 and 2003 (respectively) to serve as biological control agents against red imported fire ants...

  5. Spectrum of Controlling and Observing Complex Networks

    E-Print Network [OSTI]

    Yan, Gang; Barzel, Baruch; Slotine, Jean-Jacques; Liu, Yang-Yu; Barabasi, Albert-Laszlo

    2015-01-01T23:59:59.000Z

    Observing and controlling complex networks are of paramount interest for understanding complex physical, biological and technological systems. Recent studies have made important advances in identifying sensor or driver nodes, through which we can observe or control a complex system. Yet, the observation uncertainty induced by measurement noise and the energy cost required for control continue to be significant challenges in practical applications. Here we show that the control energy cost and the observation uncertainty vary widely in different directions of the state space. In particular, we find that if all nodes are directly driven, control is energetically feasible, as the maximum energy cost increases sublinearly with the system size. If, however, we aim to control a system by driving only a single node, control in some directions is energetically prohibitive, increasing exponentially with the system size. For the cases in between, the maximum energy decays exponentially if we increase the number of driv...

  6. Aspects of the political economy of development and synthetic biology

    E-Print Network [OSTI]

    Wellhausen, Rachel

    What implications might synthetic biology’s potential as a wholly new method of production have for the world economy, particularly developing countries? Theories of political economy predict that synthetic biology can ...

  7. ASTRONOMY BIOLOGY CHEMISTRY COMPUTER-SCIENCE GEOGRAPHY MATHEMATICS PHYSICS STATISTICS

    E-Print Network [OSTI]

    Bernstein, Phil

    BIOMEDICAL-ENGINEERING ELECTRONIC- ENGINEERING ASTRONOMY BIOLOGY CHEMISTRY COMPUTER-SCIENCE GEOGRAPHY MATHEMATICS PHYSICS STATISTICS HEALTHCARE BIOMEDICAL-ENGINEERING ELECTRONIC-ENGINEERING ASTRONOMY BIOLOGY C H HEALTHCARE BIOMEDICAL-ENGINEERING ELECTRONIC-ENGINEERING ASTRONOMY BIOLOGY CHEMISTRY COMPUTER

  8. Crafting life : a sensory ethnography of fabricated biologies

    E-Print Network [OSTI]

    Roosth, Hannah Sophia

    2010-01-01T23:59:59.000Z

    This ethnography tracks a diverse set of practices I term "constructive biologies," by which I mean efforts in the post-genomic life sciences to understand how biology works by making new biological things. I examine five ...

  9. What rough beast? Synthetic Biology and the Future of Biosecurity

    E-Print Network [OSTI]

    Mohr, Scott C.

    Synthetic biology seeks to create modular biological parts that can be assembled into useful devices, allowing the modification of biological systems with greater reliability, at lower cost, with greater speed, and by a ...

  10. Method of measurement in biological systems

    DOE Patents [OSTI]

    Turteltaub, K.W.; Vogel, J.S.; Felton, J.S.; Gledhill, B.L.; Davis, J.C.

    1994-12-27T23:59:59.000Z

    Disclosed is a method of quantifying molecules in biological substances comprising: a. selecting a biological host in which radioisotopes are present in concentrations equal to or less than those in the ambient biosphere, b. preparing a long-lived radioisotope labeled reactive chemical specie, c. administering the chemical specie to the biological host in doses sufficiently low to avoid significant overt damage to the biological system, d. allowing a period of time to elapse sufficient for dissemination and interaction of the chemical specie with the host throughout the biological system of the host, e. isolating a reacted fraction of the biological substance from the host in a manner sufficient to avoid contamination of the substance from extraneous sources, f. converting the fraction of biological substance by suitable means to a material which efficiently produces charged ions in at least one of several possible ion sources without introduction of significant isotopic fractionation, and, g. measuring the radioisotope concentration in the material by means of direct isotopic counting. 5 figures.

  11. Coke cake behavior under compressive forces

    SciTech Connect (OSTI)

    Watakabe, S.; Takeda, T.; Itaya, H.; Suginobe, H.

    1997-12-31T23:59:59.000Z

    The deformation of the coke cake and load on the side wall during pushing were studied using an electric furnace equipped with a movable wall. Coke cake was found to deform in three stages under compressive forces. The coke cake was shortened in the pushing direction in the cake deformation stage, and load was generated on the side walls in the high wall load stage. Secondary cracks in the coke cake were found to prevent load transmission on the wall. The maximum load transmission rate was controlled by adjusting the maximum fluidity and mean reflectance of the blended coal.

  12. Crystal growth under external electric fields

    SciTech Connect (OSTI)

    Uda, Satoshi; Koizumi, Haruhiko; Nozawa, Jun; Fujiwara, Kozo [Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan)

    2014-10-06T23:59:59.000Z

    This is a review article concerning the crystal growth under external electric fields that has been studied in our lab for the past 10 years. An external field is applied electrostatically either through an electrically insulating phase or a direct injection of an electric current to the solid-interface-liquid. The former changes the chemical potential of both solid and liquid and controls the phase relationship while the latter modifies the transport and partitioning of ionic solutes in the oxide melt during crystallization and changes the solute distribution in the crystal.

  13. APS controls overview

    SciTech Connect (OSTI)

    NONE

    1996-02-01T23:59:59.000Z

    The APS accelerator control system described in this report is a distributed system consisting of operator interfaces, a network, and interfaces to hardware. The operator interface is a UNIX-based workstation with an X-windows graphical user interface. The workstation may be located at any point on the facility network and maintain full functionality. The user has the ability to generate and alter control displays and to access the alarm handler, the archiver, interactive control programs, custom code, and other tools. The TCP/EP networking protocol has been selected as the underlying protocol for the control system network. TCP/EP is a commercial standard and readily available from network hardware vendors. Its implementation is independent of the particular network medium selected to implement the controls network. In the development environment copper Ethernet is the network medium; however, in the actual implementation a fiber-based system using hub technology will be utilized. The function of the network is to provide a generalized communication path between the host computers, operator workstations, input/output crates, and other hardware that comprise the control system.

  14. An adaptive observer for hyperbolic systems with application to UnderBalanced

    E-Print Network [OSTI]

    Boyer, Edmond

    an UnderBalanced well. While a well is being drilled, a fluid circulates through the drilling system. The drilling fluid cools down the drillbit, and evacuates rock cuttings. More importantly, it pressurizes fluid is controlled by a valve, which enables tighter control of the pressure. UnderBalanced Drilling

  15. Ground Control

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Control Also inside this issue: Special Science Call Projects Underway Two Postdoc Opportunities Announced Brown Carbon Review Paper Published Understanding Metal Reduction...

  16. advanced biological treatment: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Patrice Ct DALHOUSIE UNIVERSITY 12;BIOL 3020.03 Advanced Cell Biology Syllabus Page 2 Course description For a cell to function Adl, Sina 2 Biological Cybernetics...

  17. XPS Analysis of Nanostructured Materials and Biological Surfaces...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Analysis of Nanostructured Materials and Biological Surfaces. XPS Analysis of Nanostructured Materials and Biological Surfaces. Abstract: This paper examines the types of...

  18. Techno-Economic Boundary Analysis of Biological Pathways to Hydrogen...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Techno-Economic Boundary Analysis of Biological Pathways to Hydrogen Production (2009) Techno-Economic Boundary Analysis of Biological Pathways to Hydrogen Production (2009)...

  19. Biologically Enhanced Carbon Sequestration: Research Needs and Opportunities

    E-Print Network [OSTI]

    Oldenburg, Curtis M.

    2008-01-01T23:59:59.000Z

    Enhancement of soil carbon sequestration by amendment withBiologically Enhanced Carbon Sequestration: Research Needson Biologically Enhanced Carbon Sequestration, October 29,

  20. BE.442 Molecular Structure of Biological Materials, Fall 2005

    E-Print Network [OSTI]

    Zhang, Shuguang, Dr.

    Basic molecular structural principles of biological materials. Molecular structures of various materials of biological origin, including collagen, silk, bone, protein adhesives, GFP, self-assembling peptides. Molecular ...

  1. A Systems Biology Approach to Infectious Disease Research: Innovating...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Systems Biology Approach to Infectious Disease Research: Innovating the Pathogen-Host Research Paradigm. A Systems Biology Approach to Infectious Disease Research: Innovating the...

  2. Comparative systems biology across an evolutionary gradient within...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    systems biology across an evolutionary gradient within the Shewanella genus . Comparative systems biology across an evolutionary gradient within the Shewanella genus . Abstract: To...

  3. Viability of Cladosporium herbarum spores under 157 nm laser and vacuum ultraviolet irradiation, low temperature (10 K) and vacuum

    SciTech Connect (OSTI)

    Sarantopoulou, E., E-mail: esarant@eie.gr; Stefi, A.; Kollia, Z.; Palles, D.; Cefalas, A. C. [National Hellenic Research Foundation, Theoretical and Physical Chemistry Institute, 48 Vassileos Constantinou Avenue, Athens 11635 (Greece); Petrou, P. S.; Bourkoula, A.; Koukouvinos, G.; Kakabakos, S. [N.C.S.R. “Demokritos”, Institute for Nuclear and Radiological Sciences, Energy, Technology and Safety, Patriarchou Gregoriou Str. Aghia Paraskevi, Athens 15310 (Greece); Velentzas, A. D. [University of Athens, Faculty of Biology, Department of Cell Biology and Biophysics, Athens 15784 (Greece)

    2014-09-14T23:59:59.000Z

    Ultraviolet photons can damage microorganisms, which rarely survive prolonged irradiation. In addition to the need for intact DNA, cell viability is directly linked to the functionality of the cell wall and membrane. In this work, Cladosporium herbarum spore monolayers exhibit high viability (7%) when exposed to 157 nm laser irradiation (412 kJm?²) or vacuum-ultraviolet irradiation (110–180 nm) under standard pressure and temperature in a nitrogen atmosphere. Spore viability can be determined by atomic-force microscopy, nano-indentation, mass, ?-Raman and attenuated reflectance Fourier-transform far-infrared spectroscopies and DNA electrophoresis. Vacuum ultraviolet photons cause molecular damage to the cell wall, but radiation resistance in spores arises from the activation of a photon-triggered signaling reaction, expressed via the exudation of intracellular substances, which, in combination with the low penetration depth of vacuum-ultraviolet photons, shields DNA from radiation. Resistance to phototoxicity under standard conditions was assessed, as was resistance to additional environmental stresses, including exposure in a vacuum, under different rates of change of pressure during pumping time and low (10 K) temperatures. Vacuum conditions were far more destructive to spores than vacuum-ultraviolet irradiation, and UV-B photons were two orders of magnitude more damaging than vacuum-ultraviolet photons. The viability of irradiated spores was also enhanced at 10 K. This work, in addition to contributing to the photonic control of the viability of microorganisms exposed under extreme conditions, including decontamination of biological warfare agents, outlines the basis for identifying bio-signaling in vivo using physical methodologies.

  4. USE OF ELECTRICITY IN THE CONTROL OF SEA LAMPREYS

    E-Print Network [OSTI]

    USE OF ELECTRICITY IN THE CONTROL OF SEA LAMPREYS Marine Biological Laboratory LIBRAKY APR 21 1153 Service, Albert M. Day, Director USE OF ELECTRICITY IN THE CONTROL OF SEA LAMPREYS: ELECTROMECHANICAL WEIRS AND TRAPS AND ELECTRICAL BARRIERS by Vernon C. Apple gate and Bernard R. Smith Fishery Research

  5. Hindawi Publishing Corporation Journal of Control Science and Engineering

    E-Print Network [OSTI]

    Grigorieva, Ellina V.

    waste water that uses air (or oxygen) and microorganisms to biologically oxidize organic pollutants 712794, 10 pages doi:10.1155/2010/712794 Research Article Minimization of Pollution Concentration equations with one bounded control. An optimal control problem of minimizing concentration of the polluted

  6. Bing Concert Hall, Under Construction

    E-Print Network [OSTI]

    Prinz, Friedrich B.

    Freidenrich Center, Under Construction Terman Engineering Center, Demolition Frost Amphitheater Ford Plaza Center Lyman Graduate Residences Sterling Quad Mirrielees Pearce Mitchell Houses Stanford Hospital

  7. Bing Concert Hall, Under Construction

    E-Print Network [OSTI]

    Prinz, Friedrich B.

    Freidenrich Center, Under Construction Terman Engineering Center, Demolition Frost Amphitheater Ford Plaza Hall Cowell Houses Schwab Residential Center Lyman Graduate Residences Sterling Quad Mirrielees Pearce

  8. Bing Concert Hall, Under Construction

    E-Print Network [OSTI]

    Prinz, Friedrich B.

    Center, Under Construction Terman Engineering Center, Demolition Frost Amphitheater Ford Plaza Galvez Houses Schwab Residential Center Lyman Graduate Residences Sterling Quad Mirrielees Pearce Mitchell

  9. Colloidal Micromotors: Controlled Directed Motion

    E-Print Network [OSTI]

    Baraban, Larysa; Makarov, Denys; Leiderer, Paul; Erbe, Artur

    2008-01-01T23:59:59.000Z

    Here we demonstrate a synthetic micro-engine, based on long-range controlled movement of colloidal particles, which is induced by a local catalytic reaction. The directed motion at long timescales was achieved by placing specially designed magnetic capped colloids in a hydrogen peroxide solution at weak magnetic fields. The control of the motion of the particles was provided by changes of the concentration of the solution and by varying the strength of the applied magnetic field. Such synthetic objects can then be used not only to understand the fundamental driving processes but also be employed as small motors in biological environments, for example, for the transportation of molecules in a controllable way.

  10. Colloidal Micromotors: Controlled Directed Motion

    E-Print Network [OSTI]

    Larysa Baraban; Christian Kreidler; Denys Makarov; Paul Leiderer; Artur Erbe

    2008-07-10T23:59:59.000Z

    Here we demonstrate a synthetic micro-engine, based on long-range controlled movement of colloidal particles, which is induced by a local catalytic reaction. The directed motion at long timescales was achieved by placing specially designed magnetic capped colloids in a hydrogen peroxide solution at weak magnetic fields. The control of the motion of the particles was provided by changes of the concentration of the solution and by varying the strength of the applied magnetic field. Such synthetic objects can then be used not only to understand the fundamental driving processes but also be employed as small motors in biological environments, for example, for the transportation of molecules in a controllable way.

  11. Biological and Chemical Approaches to Diseases

    E-Print Network [OSTI]

    Morimoto, Richard

    , chaperones, heat shock response, protein folding and misfolding, unfolded protein response Abstract Many that proteostasis is influenced both by an adjustable proteostasis network capacity and protein folding energetics INTRODUCTION . . . . . . . . . . . . . . . . . . 960 PROTEIN FOLDING IN VITRO . . . 961 BIOLOGICALLY ASSISTED

  12. VEHICLE OPERATING PROCEDURES DEPARTMENT OF BIOLOGICAL SCIENCE

    E-Print Network [OSTI]

    Ronquist, Fredrik

    VEHICLE OPERATING PROCEDURES DEPARTMENT OF BIOLOGICAL SCIENCE GENERAL INFORMATION Vehicles resposniblity and disciplinary action. Vehicles may be used by faculty or staff from other departments complete the vehicle usage agreement form certifying that they have a valid driver's license

  13. Technical Working Group on Biological Evidence Preservation

    E-Print Network [OSTI]

    Perkins, Richard A.

    of Forensic Science (AAFS) Annual Meeting Thursday, February 20, 2014 #12;The State of Biological Evidence Dennis Davenport, Senior Crime Scene Investigator, Commerce City PD Rock Harmon, Consultant, DNARock

  14. BIOMEDICAL ENGINEERING CHEMICAL AND BIOLOGICAL ENGINEERING

    E-Print Network [OSTI]

    Heller, Barbara

    BIOMEDICAL ENGINEERING CHEMICAL AND BIOLOGICAL ENGINEERING CIVIL, ARCHITECTURAL, AND ENVIRONMENTAL ENGINEERING ELECTRICAL AND COMPUTER ENGINEERING MECHANICAL, MATERIALS, AND AEROSPACE ENGINEERING COLLEGE OF ENGINEERING IIT ARMOUR #12;WHY ENGINEERINGAT IIT ARMOUR? Five Departments. One Distinctive Educational

  15. BIOLOGICAL & AGRICULTURAL ENGINEERING DEPARTMENT POSITION ANNOUNCEMENT

    E-Print Network [OSTI]

    BIOLOGICAL & AGRICULTURAL ENGINEERING DEPARTMENT POSITION ANNOUNCEMENT Position Title: Assistant/Associate Professor and Extension Specialist (Water/Wastewater Engineering) Appointment: 70% Texas A&M Agri) and other environmental issues of concern to rural communities, agricultural producers, agri

  16. The Biology of Some Kansas Eumenidae

    E-Print Network [OSTI]

    Isely, Dwight

    1913-01-01T23:59:59.000Z

    This paper is based on field observations and collections made by the author while connected with the Biological Survey of the University of Kansas, in Northwestern Kansas, during the summer of 1912. Specimens of fully ...

  17. Stochastic modeling of biological sequence evolution

    E-Print Network [OSTI]

    Xu, Keyuan

    2005-01-01T23:59:59.000Z

    Markov models of sequence evolution are a fundamental building block for making inferences in biological research. This thesis reviews several major techniques developed to estimate parameters of Markov models of sequence ...

  18. Biological applications of weal polyelectrolyte multilayers

    E-Print Network [OSTI]

    Berg, Michael C., Ph. D. Massachusetts Institute of Technology

    2005-01-01T23:59:59.000Z

    This thesis research focused on biological applications of ultra-thin weak polyelectrolyte multilayers with specific emphasis on cell patterning, drug delivery, and antibacterial coatings. All of these very different ...

  19. Genetics and molecular biology of breast cancer

    SciTech Connect (OSTI)

    King, M.C. [California Univ., Berkeley, CA (United States); Lippman, M. [Georgetown Univ. Medical Center, Washington, DC (United States)] [comps.

    1992-12-31T23:59:59.000Z

    This volume contains the abstracts of oral presentations and poster sessions presented at the Cold Springs Harbor Meeting on Cancer Cells, this meeting entitled Genetics and Molecular Biology of Breast Cancer.

  20. Elizabeth R. Dumont Department of Biology

    E-Print Network [OSTI]

    Dumont, Elizabeth R.

    collection on the biology- engineering interface" (P.I.) Direct Costs: $670,425 (includes $7,500 REU, UMass Amherst. 2007 Plenary Speaker, 14th International Bat Research Congress, Merida, Mexico 2006

  1. Complexity and Systems Biology of Microbial Biofuels

    E-Print Network [OSTI]

    Rand, David

    Complexity and Systems Biology of Microbial Biofuels 20-24 June 2011 (All and issues Theme: Biofuel systems and issues (Chair: Nigel Burroughs) 13 (Bielefeld) Biofuels from algae- challenges for industrial levels

  2. TCD-IISc Symposium "Chemistry & Chemical Biology"

    E-Print Network [OSTI]

    O'Mahony, Donal E.

    actinide chemistry, with a focus on coordination and organometallic uranium chemistry. Paula ColavitaTCD-IISc Symposium "Chemistry & Chemical Biology" Trinity College Clive Williams, Dean of Chemistry. Research areas include supramolecular organic and inorganic chemistry and medicinal chemistry

  3. Nanotechnology: emerging tools for biology and medicine

    E-Print Network [OSTI]

    Wong, Ian Y.

    Historically, biomedical research has been based on two paradigms. First, measurements of biological behaviors have been based on bulk assays that average over large populations. Second, these behaviors have then been ...

  4. Statistical methods to infer biological interactions

    E-Print Network [OSTI]

    Tucker, George Jay

    2014-01-01T23:59:59.000Z

    Biological systems are extremely complex, and our ability to experimentally measure interactions in these systems is limited by inherent noise. Technological advances have allowed us to collect unprecedented amounts of raw ...

  5. Size adjustable separation of biologically active molecules

    E-Print Network [OSTI]

    Gutierrez, Mauricio R. (Mauricio Roberto)

    2004-01-01T23:59:59.000Z

    Separation of biologically active molecules (BAM's) is a problem for the pharmaceutical and biotechnology industries. Current technologies addressing this problem require too many techniques, toxic additives, and time to ...

  6. Biodegradation of triclosan and formation of methyl-triclosan in activated sludge under aerobic conditions

    E-Print Network [OSTI]

    Kolaei, Alireza Rezania

    Biodegradation of triclosan and formation of methyl-triclosan in activated sludge under aerobic in activated sludge from a standard activated sludge WWTP equipped with enhanced biological phosphorus removal) and anaerobic conditions rather low removal rates were determined. In a laboratory-scale activated sludge

  7. LANDFILL OPERATION FOR CARBON SEQUESTRATION AND MAXIMUM METHANE EMISSION CONTROL

    SciTech Connect (OSTI)

    Don Augenstein; Ramin Yazdani; Rick Moore; Michelle Byars; Jeff Kieffer; Professor Morton Barlaz; Rinav Mehta

    2000-02-26T23:59:59.000Z

    Controlled landfilling is an approach to manage solid waste landfills, so as to rapidly complete methane generation, while maximizing gas capture and minimizing the usual emissions of methane to the atmosphere. With controlled landfilling, methane generation is accelerated to more rapid and earlier completion to full potential by improving conditions (principally moisture, but also temperature) to optimize biological processes occurring within the landfill. Gas is contained through use of surface membrane cover. Gas is captured via porous layers, under the cover, operated at slight vacuum. A field demonstration project has been ongoing under NETL sponsorship for the past several years near Davis, CA. Results have been extremely encouraging. Two major benefits of the technology are reduction of landfill methane emissions to minuscule levels, and the recovery of greater amounts of landfill methane energy in much shorter times, more predictably, than with conventional landfill practice. With the large amount of US landfill methane generated, and greenhouse potency of methane, better landfill methane control can play a substantial role both in reduction of US greenhouse gas emissions and in US renewable energy. The work described in this report, to demonstrate and advance this technology, has used two demonstration-scale cells of size (8000 metric tons [tonnes]), sufficient to replicate many heat and compaction characteristics of larger ''full-scale'' landfills. An enhanced demonstration cell has received moisture supplementation to field capacity. This is the maximum moisture waste can hold while still limiting liquid drainage rate to minimal and safely manageable levels. The enhanced landfill module was compared to a parallel control landfill module receiving no moisture additions. Gas recovery has continued for a period of over 4 years. It is quite encouraging that the enhanced cell methane recovery has been close to 10-fold that experienced with conventional landfills. This is the highest methane recovery rate per unit waste, and thus progress toward stabilization, documented anywhere for such a large waste mass. This high recovery rate is attributed to moisture, and elevated temperature attained inexpensively during startup. Economic analyses performed under Phase I of this NETL contract indicate ''greenhouse cost effectiveness'' to be excellent. Other benefits include substantial waste volume loss (over 30%) which translates to extended landfill life. Other environmental benefits include rapidly improved quality and stabilization (lowered pollutant levels) in liquid leachate which drains from the waste.

  8. Molecular Mechanism of Biological Proton Transport

    SciTech Connect (OSTI)

    Pomes, R.

    1998-09-01T23:59:59.000Z

    Proton transport across lipid membranes is a fundamental aspect of biological energy transduction (metabolism). This function is mediated by a Grotthuss mechanism involving proton hopping along hydrogen-bonded networks embedded in membrane-spanning proteins. Using molecular simulations, the authors have explored the structural, dynamic, and thermodynamic properties giving rise to long-range proton translocation in hydrogen-bonded networks involving water molecules, or water wires, which are emerging as ubiquitous H{sup +}-transport devices in biological systems.

  9. Frontiers of NMR in Molecular Biology

    SciTech Connect (OSTI)

    NONE

    1999-08-25T23:59:59.000Z

    NMR spectroscopy is expanding the horizons of structural biology by determining the structures and describing the dynamics of blobular proteins in aqueous solution, as well as other classes of proteins including membrane proteins and the polypeptides that form the aggregates diagnostic of prion and amyloid diseases. Significant results are also emerging on DNA and RNA oligomers and their complexes with proteins. This meeting focused attention on key structural questions emanating from molecular biology and how NMR spectroscopy can be used to answer them.

  10. COMPARING FOREST MANAGEMENT PRACTICES UNDER

    E-Print Network [OSTI]

    COMPARING FOREST MANAGEMENT PRACTICES UNDER COMMUNITY-BASED AND CONVENTIONAL TENURES IN BRITISH OF MASTER OF RESOURCE MANAGEMENT In the School of Resource and Environmental Management © David Mealiea 2011 of Canada, this work may be reproduced, without authorization, under the conditions for Fair Dealing

  11. A network biology approach to denitrification in Pseudomonas aeruginosa

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Arat, Seda; Bullerjahn, George S.; Laubenbacher, Reinhard

    2015-02-23T23:59:59.000Z

    Pseudomonas aeruginosa is a metabolically flexible member of the Gammaproteobacteria. Under anaerobic conditions and the presence of nitrate, P. aeruginosa can perform (complete) denitrification, a respiratory process of dissimilatory nitrate reduction to nitrogen gas via nitrite (NO?), nitric oxide (NO) and nitrous oxide (N?O). This study focuses on understanding the influence of environmental conditions on bacterial denitrification performance, using a mathematical model of a metabolic network in P. aeruginosa. To our knowledge, this is the first mathematical model of denitrification for this bacterium. Analysis of the long-term behavior of the network under changing concentration levels of oxygen (O?), nitrate (NO?),more »and phosphate (PO?) suggests that PO? concentration strongly affects denitrification performance. The model provides three predictions on denitrification activity of P. aeruginosa under various environmental conditions, and these predictions are either experimentally validated or supported by pertinent biological literature. One motivation for this study is to capture the effect of PO? on a denitrification metabolic network of P. aeruginosa in order to shed light on mechanisms for greenhouse gas N?O accumulation during seasonal oxygen depletion in aquatic environments such as Lake Erie (Laurentian Great Lakes, USA). Simulating the microbial production of greenhouse gases in anaerobic aquatic systems such as Lake Erie allows a deeper understanding of the contributing environmental effects that will inform studies on, and remediation strategies for, other hypoxic sites worldwide.« less

  12. Nuclear reactor control column

    SciTech Connect (OSTI)

    Bachovchin, D.M.

    1982-08-10T23:59:59.000Z

    The nuclear reactor control column comprises a column disposed within the nuclear reactor core having a variable cross-section hollow channel and containing balls whose vertical location is determined by the flow of the reactor coolant through the column. The control column is divided into three basic sections wherein each of the sections has a different cross-sectional area. The uppermost section of the control column has the greatest crosssectional area, the intermediate section of the control column has the smallest cross-sectional area, and the lowermost section of the control column has the intermediate cross-sectional area. In this manner, the area of the uppermost section can be established such that when the reactor coolant is flowing under normal conditions therethrough, the absorber balls will be lifted and suspended in a fluidized bed manner in the upper section. However, when the reactor coolant flow falls below a predetermined value, the absorber balls will fall through the intermediate section and into the lowermost section, thereby reducing the reactivity of the reactor core and shutting down the reactor.

  13. Nuclear reactor control column

    DOE Patents [OSTI]

    Bachovchin, Dennis M. (Plum Borough, PA)

    1982-01-01T23:59:59.000Z

    The nuclear reactor control column comprises a column disposed within the nuclear reactor core having a variable cross-section hollow channel and containing balls whose vertical location is determined by the flow of the reactor coolant through the column. The control column is divided into three basic sections wherein each of the sections has a different cross-sectional area. The uppermost section of the control column has the greatest cross-sectional area, the intermediate section of the control column has the smallest cross-sectional area, and the lowermost section of the control column has the intermediate cross-sectional area. In this manner, the area of the uppermost section can be established such that when the reactor coolant is flowing under normal conditions therethrough, the absorber balls will be lifted and suspended in a fluidized bed manner in the upper section. However, when the reactor coolant flow falls below a predetermined value, the absorber balls will fall through the intermediate section and into the lowermost section, thereby reducing the reactivity of the reactor core and shutting down the reactor.

  14. Embedded Controllers Control. Connectivity. Security.

    E-Print Network [OSTI]

    Grantner, Janos L.

    Application Summary MCF5282 HVAC and Security Control Panel Application Summary MCF5307 Music Media Player controllers to help get their products to market quickly and cost-effectively. Aggressive price of continuous innovative technology--provides customers with the opportunity to build market share

  15. Optimal trajectory design under uncertainty

    E-Print Network [OSTI]

    Saunders, Benjamin R. (Benjamin Robert)

    2012-01-01T23:59:59.000Z

    Reference trajectory design for atmospheric reentry vehicles can be accomplished through trajectory optimization using optimal control techniques. However, this method generally focuses on nominal vehicle performance and ...

  16. CUNY EXPORT CONTROL PROCEDURES 2. Export Control Oversight: Who is Responsible

    E-Print Network [OSTI]

    Rosen, Jay

    CUNY EXPORT CONTROL PROCEDURES 2. Export Control Oversight: Who is Responsible Under the U.S. export control regulations, any individual or institution that is undertaking any export activity for Research (hereinafter referenced as "OVCR") is committed to supporting CUNY's export compliance program

  17. Control Design for Interconnected Power Systems with OLTCs via Robust Decentralized Control

    E-Print Network [OSTI]

    Pota, Himanshu Roy

    Control Design for Interconnected Power Systems with OLTCs via Robust Decentralized Control the problem of designing a decentralized control of interconnected power systems, with OLTC and SVCs, under are adjusted for variations in power system model due to large changes in loads. The only feedback needed

  18. Motion Control of Tetrahymena pyriformis Cells with Artificial Magnetotaxis: Model Predictive Control (MPC) Approach

    E-Print Network [OSTI]

    Julius, Anak Agung

    -- The use of live microbial cells as microscale robots is an attractive premise, primarily because eukaryotic cell. Whitesides et al [10] demonstrated the biological propul- sion of microscale loadsMotion Control of Tetrahymena pyriformis Cells with Artificial Magnetotaxis: Model Predictive

  19. Biology Division progress report, October 1, 1984-September 30, 1985

    SciTech Connect (OSTI)

    Not Available

    1986-01-01T23:59:59.000Z

    The body of this report provides summaries of the aims, scope and progress of the research by groups of investigators in the Division during the period of October 1, 1984, through September 30, 1985. At the end of each summary is a list of publications covering the same period. For convenience, the summaries are assembled under Sections in accordance with the current organizational structure of the Biology Division; each Section begins with an overview. It will be apparent, however, tha crosscurrents run throughout the Division and that the various programs support and interact with each other. In addition, this report includes information on the Division's educational activities, Advisory Committee, seminar program, and international interactions, as well as extramural activities of staff members, abstracts for technical meetings, and funding and personnel levels.

  20. BCTR: Biological and Chemical Technologies Research 1994 annual summary report

    SciTech Connect (OSTI)

    Petersen, G.

    1995-02-01T23:59:59.000Z

    The annual summary report presents the fiscal year (FY) 1994 research activities and accomplishments for the United States Department of Energy (DOE) Biological and Chemical Technologies Research (BCTR) Program of the Advanced Industrial Concepts Division (AICD). This AICD program resides within the Office of Industrial Technologies (OIT) of the Office of Energy Efficiency and Renewable Energy (EE). Although the OIT was reorganized in 1991 and AICD no longer exists, this document reports on efforts conducted under the former structure. The annual summary report for 1994 (ASR 94) contains the following: program description (including BCTR program mission statement, historical background, relevance, goals and objectives); program structure and organization, selected technical and programmatic highlights for 1994; detailed descriptions of individual projects; a listing of program output, including a bibliography of published work; patents, and awards arising from work supported by BCTR.