National Library of Energy BETA

Sample records for tu res fo

  1. Tu3Og,

    Office of Legacy Management (LM)

    NV, 03 CP-36 April 17, 194' - Princeton University ~caz The specific heat of Tu3C3was determined accurately. The reaction of tuballoy with six ceramic materials at specified high temperatures is indicated. \ W-92 May 23, 1942 - New York University The specific heat and thermal conductivity of' tuballoy at room temperature are given. CP-92 Kay 23, 1942 - Princeton University Tu3Og, Thermal conductivity measurements of graphite, BeO, and Tu02 were made. CP-124 June 13, 1942 - Princet,Fn University

  2. Tu Transformas | Open Energy Information

    Open Energy Info (EERE)

    Efficiency, Renewable Energy Product: Tu Transformas is a Spain-based company with business practices in carbon management consultancy, renewable energy development, and...

  3. RES Wisconsin

    Broader source: Energy.gov [DOE]

    The National Center for American Indian Enterprise Development (The National Center) is proud to announce RES Wisconsin, which will be held October 6th – 9th, 2014 at the Potawatomi Hotel & Casino in Milwaukee, Wisconsin.

  4. PaTu Wind Farm | Open Energy Information

    Open Energy Info (EERE)

    PaTu Wind Farm Jump to: navigation, search Name PaTu Wind Farm Facility PaTu Wind Farm Sector Wind energy Facility Type Commercial Scale Wind Facility Status In Service Developer...

  5. RES D.C.

    Broader source: Energy.gov [DOE]

    The National Center for American Indian Enterprise Development is hosting Reservation Economic Summit (RES), a four-day event that provides Native American businesses and entrepreneurs with the...

  6. RES Las Vegas

    Broader source: Energy.gov [DOE]

    The National Center for American Indian Enterprise Development is hosting RES Las Vegas including a tradeshow, business expo, procurement, and more on March 9-12, 2015.

  7. National RES Las Vegas

    Broader source: Energy.gov [DOE]

    RES Las Vegas is another multifaceted event from The National Center which will feature unparalleled access to respected tribal leaders, members of congress, federal agency representatives, state...

  8. RES Oklahoma 2016

    Broader source: Energy.gov [DOE]

    The National Center for American Indian Enterprise Development is hosting RES Oklahoma. The four-day conference includes events, tradeshow, business expo, procurement, and more.

  9. RES Las Vegas

    Broader source: Energy.gov [DOE]

    The National Reservation Economic Summit (RES) is taking place March 21–24, 2016, in Las Vegas. RES offers attendees access to tribal leaders, members of Congress, federal agency representatives, state and local elected officials, and top CEOs, on a national platform. Attendees will benefit from networking, training, and business development sessions.

  10. Eole RES | Open Energy Information

    Open Energy Info (EERE)

    Eole RES Jump to: navigation, search Name: Eole-RES Place: AVIGNON, France Zip: F-84000 Sector: Wind energy Product: EOLE-RES's expertise lies in the conception, development,...

  11. RES D.C.

    Broader source: Energy.gov [DOE]

    The National Center for American Indian Enterprise Development is hosting Reservation Economic Summit (RES), a four-day event that provides Native American businesses and entrepreneurs with the tools they need to be successful.

  12. 2013 guidance fo real Property Inventory Reporting | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    guidance fo real Property Inventory Reporting 2013 guidance fo real Property Inventory Reporting SIGNED_FY13_Rpt_Instructions REV - 2013.08.15.pdf (586.39 KB) More Documents & Publications FY 2012 Federal Real Property Reporting Requirement FY09_Federal_Real_Property_Reporting_Requirements.pdf Guidance for Fiscal Year 2015 Facilities Information Management System Data Validations

  13. RES Las Vegas 2016

    Broader source: Energy.gov [DOE]

    Hosted by the National Center for American Indian Enterprise Development, Reservation Economic Summit (RES) is a four-day conference featuring training and business development opportunities, a tribal business leaders forum, a tradeshow and business expo featuring hundreds of exhibitors, and more!

  14. RES New Mexico

    Broader source: Energy.gov [DOE]

    Hosted by the National Center for American Indian Enterprise Development, Reservation Economic Summit (RES) is a four-day conference featuring training and business development opportunities, a tribal business leaders forum, a tradeshow and business expo featuring hundreds of exhibitors, and more!

  15. RES North America LLC | Open Energy Information

    Open Energy Info (EERE)

    RES North America LLC Jump to: navigation, search Name: RES North America LLC Place: Portland, Oregon Zip: 97258 Sector: Wind energy Product: US development arm of RES Ltd....

  16. RES Anatolia | Open Energy Information

    Open Energy Info (EERE)

    navigation, search Name: RES Anatolia Place: Istanbul, Turkey Zip: 34398 Sector: Solar, Wind energy Product: Istanbul-based subsidiary formed due to positive forecasts for the...

  17. ITP Steel: Energy and Environmental Profile fo the U.S. Iron...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy and Environmental Profile fo the U.S. Iron and Steel Industry ITP Steel: Energy and Environmental Profile fo the U.S. Iron and Steel Industry steelprofile.pdf (581.28 KB) ...

  18. Renewable Energy Systems (RES UK and Ireland) | Open Energy Informatio...

    Open Energy Info (EERE)

    (RES UK and Ireland) Jump to: navigation, search Logo: Renewable Energy Systems (RES UK and Ireland) Name: Renewable Energy Systems (RES UK and Ireland) Address: Beaufort Court Egg...

  19. Renewable Energy Systems Inc (RES Americas) (Colorado) | Open...

    Open Energy Info (EERE)

    Inc (RES Americas) (Colorado) Jump to: navigation, search Logo: Renewable Energy Systems Inc (RES Americas) Name: Renewable Energy Systems Inc (RES Americas) Address: 11101 W....

  20. I RADIOLOGICAL SCOPING SURVEY OF FO,RMER MONSANTO' FACILITIES

    Office of Legacy Management (LM)

    -I a.d *4dk *-f--l- --- I. ,e-- - .- --_ -- -. ;,. -* " . I . RADIOLOGICAL SCOPING SURVEY OF FO,RMER MONSANTO' FACILITIES (Unit XII and W a rehouse) DAYTON, OHIO Report Date: 4 September 1997 Survey Dak 27 Aitgust 1991 Prepared by: Mark L. Mays, Chief Radiation Safety Branch Sponsored by: M iamisburg Environmental Matigement Reject Office Ohio FTekl Ofice U.S.. Department of Energy Conducted by: %diation Safety Branch Of&e of Environmental Management ggtb Air Base W ing U.S. Departmtnt

  1. RES Americas Inc | Open Energy Information

    Open Energy Info (EERE)

    Inc Place: Broomfield, Colorado Zip: 80021 Product: United States and Canada development arm of RES Group. References: RES Americas Inc1 This article is a stub. You can help...

  2. RES GmbH | Open Energy Information

    Open Energy Info (EERE)

    RES GmbH Jump to: navigation, search Name: RES GmbH Place: Saalfeld, Germany Zip: D - 07318 Sector: Renewable Energy Product: Develops, manufactures and distributes systems based...

  3. Cal. Pub. Res. Code 30330 | Open Energy Information

    Open Energy Info (EERE)

    Pub. Res. Code 30330Legal Abstract Cal. Pub. Res. Code 30330, current through August 5, 2014. Published NA Year Signed or Took Effect 1976 Legal Citation Cal. Pub. Res....

  4. Cal. Pub. Res. Code 30600 | Open Energy Information

    Open Energy Info (EERE)

    Pub. Res. Code 30600Legal Abstract Cal. Pub. Res. Code 30600, current through August 5, 2014. Published NA Year Signed or Took Effect 1976 Legal Citation Cal. Pub. Res....

  5. Cal. Pub. Res. Code 30413 | Open Energy Information

    Open Energy Info (EERE)

    Pub. Res. Code 30413Legal Abstract Cal. Pub. Res. Code 30413, current through August 5, 2014. Published NA Year Signed or Took Effect 1991 Legal Citation Cal. Pub. Res....

  6. Cal. Pub. Res. Code 30264 | Open Energy Information

    Open Energy Info (EERE)

    Pub. Res. Code 30264Legal Abstract Cal. Pub. Res. Code 30264, current through August 5, 2014. Published NA Year Signed or Took Effect 1976 Legal Citation Cal. Pub. Res....

  7. Renewable Energy Systems (RES Mediterranean) | Open Energy Information

    Open Energy Info (EERE)

    Mediterranean) Jump to: navigation, search Logo: Renewable Energy Systems (RES Mediterranean) Name: Renewable Energy Systems (RES Mediterranean) Address: 330 rue du Mourelet Z.I....

  8. Renewable Energy Systems (RES Scandinavia) | Open Energy Information

    Open Energy Info (EERE)

    Scandinavia) Jump to: navigation, search Logo: Renewable Energy Systems (RES Scandinavia) Name: Renewable Energy Systems (RES Scandinavia) Address: Lilla Bommen 1 Place:...

  9. Renewable Energy Systems (RES Australia and New Zealand) | Open...

    Open Energy Info (EERE)

    Australia and New Zealand) Jump to: navigation, search Logo: Renewable Energy Systems (RES Australia and New Zealand) Name: Renewable Energy Systems (RES Australia and New Zealand)...

  10. Compiling RES Legislation for Kazakhstan | Open Energy Information

    Open Energy Info (EERE)

    for Kazakhstan1 Compiling RES Legislation for Kazakhstan Potential of renewable energy sources usage in the Republic of Kazakhstan Report on Benefits of RES to Energy...

  11. WA_00_022_CARGILL_DOW_POLYMERS_LLC_Waiver_of_Domestic_and_Fo.pdf |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy 22_CARGILL_DOW_POLYMERS_LLC_Waiver_of_Domestic_and_Fo.pdf WA_00_022_CARGILL_DOW_POLYMERS_LLC_Waiver_of_Domestic_and_Fo.pdf (1.38 MB) More Documents & Publications WA_04_033_CARGILL_Waiver_of_Patent_Rights_to_CARGILL_DOWN_L.pdf WA_03_029_CARGILL_DOW_LLC_Waiver_of_Domestic_and_Foreign_Pat.pdf WA_02_052_CARGILL_DOW_Waiver_of_Domestic_and_Foreign_Patent_

  12. Property:Res cons | Open Energy Information

    Open Energy Info (EERE)

    the property "Res cons" Showing 25 pages using this property. (previous 25) (next 25) 4 4-County Electric Power Assn (Mississippi) EIA Revenue and Sales - April 2008 + 35,751 +...

  13. RES-E-NEXT: Next Generation of RES-E Policy Instruments

    SciTech Connect (OSTI)

    Miller, M.; Bird, L.; Cochran, J.; Milligan, M.; Bazilian, M.; Denny, E.; Dillon, J.; Bialek, J.; O'Malley, M.; Neuhoff, K.

    2013-07-04

    The rapid deployment of renewable sources of electricity (RES-E) is transforming power systems globally. This trend is likely to continue with large increases in investment and deployment of RES-E capacity over the coming decades. Several countries now have penetration levels of variable RES-E generation (i.e., wind and solar) in excess of 15% of their annual electricity generation; and many jurisdictions (e.g., Spain, Portugal, Ireland, Germany, and Denmark; and, in the United States, Colorado) have experienced instantaneous penetration levels of more than 50% variable generation.1 These penetration levels of variable RES-E have prompted many jurisdictions to begin modifying practices that evolved in an era of readily dispatchable, centralised power systems. Providing insights for the transition to high levels of variable RES-E generation is the focus of this document, which is the final report of the RES-E-NEXT project commissioned by the International Energy Agency’s implementing agreement on Renewable Energy Technology Deployment (IEA-RETD). It presents a comprehensive assessment of issues that will shape power system evolution during the transition to high levels of variable RES-E generation. While policy will be a central tool to sustain the growth of RES-E capacity and to enable power system transitions, the scope of the report extends beyond policy considerations to include the related domains of regulation, power market design, and system operation protocols. This broad scope is in recognition that a changing resource mix with greater penetration levels of variable RES-E has broad implications for grid operations, wholesale and retail power markets, and infrastructure needs. The next decade will be a critical transition period for power system stakeholders, as global deployment of RES-E capacity (and especially variable RES-E capacity) continues to scale-up in many regions of the world. To address increased penetration levels of RES-E in power systems

  14. Energy requirements of the switchable polarity solvent forward osmosis (SPS-FO) water purification process

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Wendt, Daniel S.; Orme, Christopher J.; Mines, Gregory L.; Wilson, Aaron D.

    2015-08-01

    A model was developed to estimate the process energy requirements of a switchable polarity solvent forward osmosis (SPS FO) system for water purification from aqueous NaCl feed solution concentrations ranging from 0.5 to 4.0 molal at an operational scale of 480 m3/day (feed stream). The model indicates recovering approximately 90% of the water from a feed solution with NaCl concentration similar to seawater using SPS FO would have total equivalent energy requirements between 2.4 and 4.3 kWh per m3 of purified water product. The process is predicted to be competitive with current costs for disposal/treatment of produced water from oilmore » and gas drilling operations. As a result, once scaled up the SPS FO process may be a thermally driven desalination process that can compete with the cost of seawater reverse osmosis.« less

  15. Energy requirements of the switchable polarity solvent forward osmosis (SPS-FO) water purification process

    SciTech Connect (OSTI)

    Wendt, Daniel S.; Orme, Christopher J.; Mines, Gregory L.; Wilson, Aaron D.

    2015-08-01

    A model was developed to estimate the process energy requirements of a switchable polarity solvent forward osmosis (SPS FO) system for water purification from aqueous NaCl feed solution concentrations ranging from 0.5 to 4.0 molal at an operational scale of 480 m3/day (feed stream). The model indicates recovering approximately 90% of the water from a feed solution with NaCl concentration similar to seawater using SPS FO would have total equivalent energy requirements between 2.4 and 4.3 kWh per m3 of purified water product. The process is predicted to be competitive with current costs for disposal/treatment of produced water from oil and gas drilling operations. As a result, once scaled up the SPS FO process may be a thermally driven desalination process that can compete with the cost of seawater reverse osmosis.

  16. Renewable Energy Systems Ltd RES Group | Open Energy Information

    Open Energy Info (EERE)

    Ltd RES Group Jump to: navigation, search Name: Renewable Energy Systems Ltd (RES Group) Place: Hertfordshire, United Kingdom Zip: WD4 8LR Sector: Wind energy Product: UK based...

  17. Cal. Pub. Res. Code 30103 | Open Energy Information

    Open Energy Info (EERE)

    search OpenEI Reference LibraryAdd to library Legal Document- StatuteStatute: Cal. Pub. Res. Code 30103Legal Abstract Cal. Pub. Res. Code 30103, current through...

  18. Cal. Pub. Res. Code 6370 | Open Energy Information

    Open Energy Info (EERE)

    Cal. Pub. Res. Code 6370 Jump to: navigation, search OpenEI Reference LibraryAdd to library Legal Document- StatuteStatute: Cal. Pub. Res. Code 6370Legal Abstract Statutory...

  19. Cal. Pub. Res. Code 25309 | Open Energy Information

    Open Energy Info (EERE)

    search OpenEI Reference LibraryAdd to library Legal Document- StatuteStatute: Cal. Pub. Res. Code 25309Legal Abstract Cal. Pub. Res. Code 25309, current through...

  20. Cal. Pub. Res. Code 6826 | Open Energy Information

    Open Energy Info (EERE)

    search OpenEI Reference LibraryAdd to library Legal Document- StatuteStatute: Cal. Pub. Res. Code 6826Legal Abstract Cal. Pub. Res. Code 6826, current through...

  1. Cal. Pub. Res. Code 25541 | Open Energy Information

    Open Energy Info (EERE)

    search OpenEI Reference LibraryAdd to library Legal Document- StatuteStatute: Cal. Pub. Res. Code 25541Legal Abstract Cal. Pub. Res. Code 25541, current through...

  2. Cal. Pub. Res. Code 25120 | Open Energy Information

    Open Energy Info (EERE)

    search OpenEI Reference LibraryAdd to library Legal Document- StatuteStatute: Cal. Pub. Res. Code 25120Legal Abstract Cal. Pub. Res. Code 25120, current through...

  3. Cal. Pub. Res. 25500 et seq | Open Energy Information

    Open Energy Info (EERE)

    search OpenEI Reference LibraryAdd to library Legal Document- StatuteStatute: Cal. Pub. Res. 25500 et seqLegal Abstract Cal. Pub. Res. Code 25531, current through...

  4. F.O. Licht's 17th Annual World Ethanol & Biofuels Conference

    Broader source: Energy.gov [DOE]

    The F.O. Licht's 17th Annual World Ethanol & Biofuels Conference will be held on November 3–6, 2014, in Budapest, Hungary. Valerie Reed, Deputy Director of the Bioenergy Technolgies Office will be serving on two panels: "Maintaining Next Generation Investments in the Years Ahead" on November 4 and "Putting Together a Constant Supply of Feedstocks for Advanced and Cellulosic Biofuels, Biochemicals and Aviation Fuels" on November 5.

  5. Microsoft Word - summer.doc

    U.S. Energy Information Administration (EIA) Indexed Site

    b trac ting fro m th e da ily a ve rag e hig h te m p e ra tu res fo r th e la st 10 y ea rs a n am o un t e qu al to tw ice a n estim ate o f the stan da rd de via tion for h igh...

  6. Cal. Pub. Res. Code 21001 | Open Energy Information

    Open Energy Info (EERE)

    Cal. Pub. Res. Code 21001Legal Abstract Sets forth California's policy on maintenance of environmental quality. Published NA Year Signed or Took Effect 1970 Legal...

  7. Renewable Energy Systems Inc (RES Americas) (Texas) | Open Energy...

    Open Energy Info (EERE)

    (Texas) Jump to: navigation, search Name: Renewable Energy Systems Inc (RES Americas) Address: 9050 Capital of Texas Hwy Place: Austin, Texas Zip: 78759 Region: Texas Area Sector:...

  8. Renewable Energy Systems Inc (RES Americas) | Open Energy Information

    Open Energy Info (EERE)

    Renewable Energy Systems Inc (RES Americas) Address: 11101 W. 120th Ave Suite 400 Place: Broomfield, Colorado Zip: 80021 Region: Pacific Northwest Area Sector: Wind energy Product:...

  9. Cal. Pub. Res. Code 21080 | Open Energy Information

    Open Energy Info (EERE)

    library Legal Document- StatuteStatute: Cal. Pub. Res. Code 21080Legal Abstract Sets forth general statutory provisions for California's environmental quality programs....

  10. Cal. Pub. Res. Code 21067 | Open Energy Information

    Open Energy Info (EERE)

    search OpenEI Reference LibraryAdd to library Legal Document- StatuteStatute: Cal. Pub. Res. Code 21067Legal Abstract Definitions section for California's...

  11. RES Oklahoma 2016: Office of Indian Energy Session on Tribal...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Office of Indian Energy Session on Tribal Energy: Strategic Roadmap 2025 RES Oklahoma 2016: Office of Indian Energy Session on Tribal Energy: Strategic Roadmap 2025 July 12, 2016 ...

  12. Facile route of biopolymer mediated ferrocene (FO) nanoparticles in aqueous dispersion

    SciTech Connect (OSTI)

    Kaus, Noor Haida Mohd.; Collins, A. M.; Mann, S.

    2014-10-24

    In this paper, we present a facile method for production stable aqueous dispersion of ferrocene (FO) nanoparticles. Ferrocene compounds were employed to achieve stable nanodispersions, stabilized with three different biopolymers namely, alginate, CM-dextran and chitosan. The nanoparticles produce are spherical, less than 10 nm in mean diameter and highly stable without any sedimentation. Fourier infrared transform (FTIR) and X-ray diffraction (XRD) studies confirmed the purity of ferrocene nanoparticles there is no modifications occur during the preparation route. FTIR spectra results were consistent with the presence of absorption band of cyclopentadienyl ring (C{sub 5}H{sub 5}{sup −} ion) which assigned to ν(C-C) vibrations (1409 cm-1), δ(C-H) stretching at 1001 cm{sup −1} and π(C-H) vibrations at 812 cm{sup −1}. Furthermore, all functional group for biopolymers such as CO from carboxyl group of CM-dextran and sodium alginate appears at 1712 cm{sup −1} and 1709 cm{sup −1} respectively, indicating there are steric repulsion interactions for particles stabilization. Powder X-ray diffraction patterns of sedimented samples of the biopolymers-stabilized ferrocene (FO) showed all reflections which were indexed respectively to the (−110), (001), (−201), (−111), (200), (−211), (210), (120) and (111) according to the monoclinic phase ferrocene. This confirmed that the products obtained were of high purity of Fe and EDAX analysis also suggests that the presence of the Fe element in the colloidal dispersion.

  13. Property:Res sales (mwh) | Open Energy Information

    Open Energy Info (EERE)

    property "Res sales (mwh)" Showing 25 pages using this property. (previous 25) (next 25) 4 4-County Electric Power Assn (Mississippi) EIA Revenue and Sales - April 2008 + 35,568 +...

  14. Property:Res rev (thousand $) | Open Energy Information

    Open Energy Info (EERE)

    "Res rev (thousand )" Showing 25 pages using this property. (previous 25) (next 25) 4 4-County Electric Power Assn (Mississippi) EIA Revenue and Sales - April 2008 + 3,675 +...

  15. Cal. Pub. Res. Code 6301 | Open Energy Information

    Open Energy Info (EERE)

    search OpenEI Reference LibraryAdd to library Legal Document- StatuteStatute: Cal. Pub. Res. Code 6301Legal Abstract This section grants the California State Lands...

  16. Cal. Pub. Res. Code 6502 | Open Energy Information

    Open Energy Info (EERE)

    search OpenEI Reference LibraryAdd to library Legal Document- StatuteStatute: Cal. Pub. Res. Code 6502Legal Abstract Statutory chapter providing for leasing of public...

  17. Cal. Pub. Res. Code 5020 et seq.: Historical Resources | Open...

    Open Energy Info (EERE)

    search OpenEI Reference LibraryAdd to library Legal Document- StatuteStatute: Cal. Pub. Res. Code 5020 et seq.: Historical ResourcesLegal Abstract This section...

  18. Cal. Pub. Res. Code 30603 | Open Energy Information

    Open Energy Info (EERE)

    navigation, search OpenEI Reference LibraryAdd to library Legal Document- OtherOther: Cal. Pub. Res. Code 30603Legal Abstract Delegation of local authority for Coastal Zone...

  19. DOE to Host Energy Track at RES 2016

    Broader source: Energy.gov [DOE]

    The U.S. Department of Energy (DOE) Office of Indian Energy is offering an energy track at the National Reservation Economic Summit (RES) March 22–23, 2016, in Las Vegas, Nevada. The track will feature breakout sessions designed to assist tribal energy leaders and professionals in developing strategic energy solutions and making informed decisions about energy projects.

  20. Display of Hi-Res Data | Princeton Plasma Physics Lab

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Display of Hi-Res Data This invention enables plotting a very large number of data points relative to the number of display pixels without losing significant information about the data. A user operating the system can set the threshold for highlighting locations on the plot that exceed a specific variance or range. Highlighted areas can be dynamically explored at the full resolution of the data. No.: M-874 Inventor(s): Eliot A Feibush

  1. NREL to Partner with RES Americas on Wind Balance-of-Plant Research - News

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Releases | NREL to Partner with RES Americas on Wind Balance-of-Plant Research June 17, 2009 The U.S. Department of Energy's (DOE) National Renewable Energy Laboratory (NREL) and Renewable Energy Systems Americas, Inc. (RES Americas) have announced a partnership to evaluate the design and performance of vital wind energy support systems. Under a Cooperative Research and Development Agreement (CRADA), NREL and RES Americas will investigate structural loads on foundations of operating wind

  2. DOE Office of Indian Energy to Sponsor Energy Forum at RES 2014 |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Sponsor Energy Forum at RES 2014 DOE Office of Indian Energy to Sponsor Energy Forum at RES 2014 February 20, 2014 - 5:14pm Addthis The DOE Office of Indian Energy is sponsoring an energy forum during the National Reservation Economic Summit (RES) 2014 conference in Las Vegas, Nevada. Part of DOE's silver-level sponsorship of RES 2014, the forum will take place on March 17, 2014, from 9 a.m.-5:30 p.m. and will feature the following roundtable sessions: Roundtable Session

  3. EPRI/NRC-RES fire human reliability analysis guidelines.

    SciTech Connect (OSTI)

    Lewis, Stuart R.; Cooper, Susan E.; Najafi, Bijan; Collins, Erin; Hannaman, Bill; Kohlhepp, Kaydee; Grobbelaar, Jan; Hill, Kendra; Hendrickson, Stacey M. Langfitt; Forester, John Alan; Julius, Jeff

    2010-03-01

    During the 1990s, the Electric Power Research Institute (EPRI) developed methods for fire risk analysis to support its utility members in the preparation of responses to Generic Letter 88-20, Supplement 4, 'Individual Plant Examination - External Events' (IPEEE). This effort produced a Fire Risk Assessment methodology for operations at power that was used by the majority of U.S. nuclear power plants (NPPs) in support of the IPEEE program and several NPPs overseas. Although these methods were acceptable for accomplishing the objectives of the IPEEE, EPRI and the U.S. Nuclear Regulatory Commission (NRC) recognized that they required upgrades to support current requirements for risk-informed, performance-based (RI/PB) applications. In 2001, EPRI and the USNRC's Office of Nuclear Regulatory Research (RES) embarked on a cooperative project to improve the state-of-the-art in fire risk assessment to support a new risk-informed environment in fire protection. This project produced a consensus document, NUREG/CR-6850 (EPRI 1011989), entitled 'Fire PRA Methodology for Nuclear Power Facilities' which addressed fire risk for at power operations. NUREG/CR-6850 developed high level guidance on the process for identification and inclusion of human failure events (HFEs) into the fire PRA (FPRA), and a methodology for assigning quantitative screening values to these HFEs. It outlined the initial considerations of performance shaping factors (PSFs) and related fire effects that may need to be addressed in developing best-estimate human error probabilities (HEPs). However, NUREG/CR-6850 did not describe a methodology to develop best-estimate HEPs given the PSFs and the fire-related effects. In 2007, EPRI and RES embarked on another cooperative project to develop explicit guidance for estimating HEPs for human failure events under fire generated conditions, building upon existing human reliability analysis (HRA) methods. This document provides a methodology and guidance for conducting

  4. TU-F-18C-09: Mammogram Surveillance Using Texture Analysis for Breast Cancer Patients After Radiation Therapy

    SciTech Connect (OSTI)

    Kuo, H; Tome, W; FOX, J; Hong, L; Yaparpalvi, R; Mehta, K; Bodner, W; Kalnicki, S

    2014-06-15

    Purpose: To study the feasibility of applying cancer risk model established from treated patients to predict the risk of recurrence on follow-up mammography after radiation therapy for both ipsilateral and contralateral breast. Methods: An extensive set of textural feature functions was applied to a set of 196 Mammograms from 50 patients. 56 Mammograms from 28 patients were used as training set, 44 mammograms from 22 patients were used as test set and the rest were used for prediction. Feature functions include Histogram, Gradient, Co-Occurrence Matrix, Run-Length Matrix and Wavelet Energy. An optimum subset of the feature functions was selected by Fisher Coefficient (FO) or Mutual Information (MI) (up to top 10 features) or a method combined FO, MI and Principal Component (FMP) (up to top 30 features). One-Nearest Neighbor (1-NN), Linear Discriminant Analysis (LDA) and Nonlinear Discriminant Analysis (NDA) were utilized to build a risk model of breast cancer from the training set of mammograms at the time of diagnosis. The risk model was then used to predict the risk of recurrence from mammogram taken one year and three years after RT. Results: FPM with NDA has the best classification power in classifying the training set of the mammogram with lesions versus those without lesions. The model of FPM with NDA achieved a true positive (TP) rate of 82% compared to 45.5% of using FO with 1-NN. The best false positive (FP) rates were 0% and 3.6% in contra-lateral breast of 1-year and 3-years after RT, and 10.9% in ipsi-lateral breast of 3-years after RT. Conclusion: Texture analysis offers high dimension to differentiate breast tissue in mammogram. Using NDA to classify mammogram with lesion from mammogram without lesion, it can achieve rather high TP and low FP in the surveillance of mammogram for patient with conservative surgery combined RT.

  5. Development of an aerosol microphysical module: Aerosol Two-dimensional bin module for foRmation and Aging Simulation (ATRAS)

    SciTech Connect (OSTI)

    Matsui, H.; Koike, Makoto; Kondo, Yutaka; Fast, Jerome D.; Takigawa, M.

    2014-09-30

    Number concentrations, size distributions, and mixing states of aerosols are essential parameters for accurate estimation of aerosol direct and indirect effects. In this study, we developed an aerosol module, designated Aerosol Two-dimensional bin module for foRmation and Aging Simulation (ATRAS), that can represent these parameters explicitly by considering new particle formation (NPF), black carbon (BC) aging, and secondary organic aerosol (SOA) processes. A two-dimensional bin representation is used for particles with dry diameters from 40 nm to 10 m to resolve both aerosol size (12 bins) and BC mixing state (10 bins) for a total of 120 bins. The particles with diameters from 1 to 40 nm are resolved using an additional 8 size bins to calculate NPF. The ATRAS module was implemented in the WRF-chem model and applied to examine the sensitivity of simulated mass, number, size distributions, and optical and radiative parameters of aerosols to NPF, BC aging and SOA processes over East Asia during the spring of 2009. BC absorption enhancement by coating materials was about 50% over East Asia during the spring, and the contribution of SOA processes to the absorption enhancement was estimated to be 10 20% over northern East Asia and 20 35% over southern East Asia. A clear north-south contrast was also found between the impacts of NPF and SOA processes on cloud condensation nuclei (CCN) concentrations: NPF increased CCN concentrations at higher supersaturations (smaller particles) over northern East Asia, whereas SOA increased CCN concentrations at lower supersaturations (larger particles) over southern East Asia. Application of ATRAS to East Asia also showed that the impact of each process on each optical and radiative parameter depended strongly on the process and the parameter in question. The module can be used in the future as a benchmark model to evaluate the accuracy of simpler aerosol models and examine interactions between NPF, BC aging, and SOA processes

  6. Attachment B Visitor Tours at TA-53 TA53-FO-121-001B.4 Preparation Checklist for Visitor Tours at TA-53

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Attachment B Visitor Tours at TA-53 TA53-FO-121-001B.4 Preparation Checklist for Visitor Tours at TA-53 This checklist provides reminders of safety and security considerations in preparation and implementation of tours at TA-53. Tour Date: Purpose of Tour or Tour Title: Tour Host and Z#: State Time and Approximate Duration: Tour Type Check all that apply: Educational Outreach/Student Tour with Minors Large Group Tour Other Tour High Level or Distinguished Work Related Tour Preparation, Visitor

  7. RES Oklahoma 2016: Office of Indian Energy Session on Tribal Energy: Strategic Roadmap 2025

    Broader source: Energy.gov [DOE]

    The U.S. Department of Energy (DOE) Office of Indian Energy will be hosting a session entitled “Tribal Energy: Strategic Roadmap 2025” at the Reservation Economic Summit (RES) taking place in Tulsa, Oklahoma, July 11–14.

  8. EPRI/NRC-RES fire PRA guide for nuclear power facilities. Volume 1, summary and overview.

    SciTech Connect (OSTI)

    Not Available

    2004-09-01

    This report documents state-of-the-art methods, tools, and data for the conduct of a fire Probabilistic Risk Assessment (PRA) for a commercial nuclear power plant (NPP) application. The methods have been developed under the Fire Risk Re-quantification Study. This study was conducted as a joint activity between EPRI and the U. S. NRC Office of Nuclear Regulatory Research (RES) under the terms of an EPRI/RES Memorandum of Understanding [RS.1] and an accompanying Fire Research Addendum [RS.2]. Industry participants supported demonstration analyses and provided peer review of this methodology. The documented methods are intended to support future applications of Fire PRA, including risk-informed regulatory applications. The documented method reflects state-of-the-art fire risk analysis approaches. The primary objective of the Fire Risk Study was to consolidate recent research and development activities into a single state-of-the-art fire PRA analysis methodology. Methodological issues raised in past fire risk analyses, including the Individual Plant Examination of External Events (IPEEE) fire analyses, have been addressed to the extent allowed by the current state-of-the-art and the overall project scope. Methodological debates were resolved through a consensus process between experts representing both EPRI and RES. The consensus process included a provision whereby each major party (EPRI and RES) could maintain differing technical positions if consensus could not be reached. No cases were encountered where this provision was invoked. While the primary objective of the project was to consolidate existing state-of-the-art methods, in many areas, the newly documented methods represent a significant advancement over previously documented methods. In several areas, this project has, in fact, developed new methods and approaches. Such advances typically relate to areas of past methodological debate.

  9. Tu3Og,

    Office of Legacy Management (LM)

    CT-192 No date - Princeton University The determination of a number of physical constants primarily ' those connected with the heat transfer in an atorhic power plant, were carried ...

  10. Grazing incidence angle based sensing approach integrated with fiber-optic Fourier transform infrared (FO-FTIR) spectroscopy for remote and label-free detection of medical device contaminations

    SciTech Connect (OSTI)

    Hassan, Moinuddin Ilev, Ilko

    2014-10-15

    Contamination of medical devices has become a critical and prevalent public health safety concern since medical devices are being increasingly used in clinical practices for diagnostics, therapeutics and medical implants. The development of effective sensing methods for real-time detection of pathogenic contamination is needed to prevent and reduce the spread of infections to patients and the healthcare community. In this study, a hollow-core fiber-optic Fourier transform infrared spectroscopy methodology employing a grazing incidence angle based sensing approach (FO-FTIR-GIA) was developed for detection of various biochemical contaminants on medical device surfaces. We demonstrated the sensitivity of FO-FTIR-GIA sensing approach for non-contact and label-free detection of contaminants such as lipopolysaccharide from various surface materials relevant to medical device. The proposed sensing system can detect at a minimum loading concentration of approximately 0.7 ?g/cm{sup 2}. The FO-FTIR-GIA has the potential for the detection of unwanted pathogen in real time.

  11. Women @ Energy: Anh Tu Quach

    Broader source: Energy.gov [DOE]

    "Science revolves around inborn curiosity; observe any baby intensely examining a colorful new object or one who repeatedly throws a toy down to see how many times the adult will pick up the toy in this “experiment” to witness this natural curiosity. We need to take care not to let that curiosity whither and die. We need to tend that fire through targeted programs, diverse mentors, and accessible resources."

  12. Letter fo Support from Research Mentor

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Postdoctoral Research Awards Letter of Support from Research Mentor Deadline: May 6, 2016 This form is to be sent directly to the applicant to upload into Zintellect as part of the application. Detailed information about the Research Awards and eligibility requirements available at: http://energy.gov/eere/education/eere-postdoctoral-research-awards Mentor Curriculum Vitae (CV): Mentor's Curriculum Vitae is to be sent directly to the applicant to upload with the Letter of Support into Zintellect

  13. Large Scale Evaluation fo Nickel Aluminide Rolls

    SciTech Connect (OSTI)

    2005-09-01

    This completed project was a joint effort between Oak Ridge National Laboratory and Bethlehem Steel (now Mittal Steel) to demonstrate the effectiveness of using nickel aluminide intermetallic alloy rolls as part of an updated, energy-efficient, commercial annealing furnace system.

  14. MHK Technologies/FO | Open Energy Information

    Open Energy Info (EERE)

    here Point Absorber Technology Readiness Level Click here TRL 1-3: Discovery Concept Definition Early Stage Development & Design & Engineering Technology Description The...

  15. HiRes deconvolved Spitzer images of 89 protostellar jets and outflows: New data on the evolution of the outflow morphology

    SciTech Connect (OSTI)

    Velusamy, T.; Langer, W. D.; Thompson, T. E-mail: William.D.Langer@jpl.nasa.gov

    2014-03-01

    To study the role of protosellar jets and outflows in the time evolution of the parent cores and the protostars, the astronomical community needs a large enough database of infrared images of protostars at the highest spatial resolution possible to reveal the details of their morphology. Spitzer provides unprecedented sensitivity in the infrared to study both the jet and outflow features, however, its spatial resolution is limited by its 0.85 m mirror. Here, we use a high-resolution deconvolution algorithm, 'HiRes,' to improve the visualization of spatial morphology by enhancing resolution (to subarcsecond levels in the IRAC bands) and removing the contaminating side lobes from bright sources in a sample of 89 protostellar objects. These reprocessed images are useful for detecting (1) wide-angle outflows seen in scattered light, (2) morphological details of H{sub 2} emission in jets and bow shocks, and (3) compact features in MIPS 24 μm images as protostar/disk and atomic/ionic line emission associated with the jets. The HiRes FITS image data of such a large homogeneous sample presented here will be useful to the community in studying these protostellar objects. To illustrate the utility of this HiRes sample, we show how the opening angle of the wide-angle outflows in 31 sources, all observed in the HiRes-processed Spitzer images, correlates with age. Our data suggest a power-law fit to opening angle versus age with an exponent of ∼0.32 and 0.02, respectively, for ages ≤8000 yr and ≥8000 yr.

  16. RES Energy Track

    Broader source: Energy.gov [DOE]

    ​The Office of Indian Energy is hosting an Energy Track featuring breakout sessions on a variety of topics, including workforce development, energy technology, and capacity building, to help tribal energy leaders and professionals make informed decisions about energy projects.

  17. Hi-Res WIPP

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Waste Isolation Pilot Plant The WIPP facility is located southeast of Carlsbad, N.M. 26miles are employed at WIPP, which includes employees supporting waste characterization and packaging activities at the generator sites. 1,000 people The U.S. Department of Energy's (DOE) WIPP facility has safely disposed of the nation's defense related transuranic (TRU) radioactive waste for the past WIPP began operations in March 1999 WIPP is the only federal repository for the nation's TRU waste TRU waste

  18. RES New Mexico

    Broader source: Energy.gov [DOE]

    Hosted by the National Center for American Indian Enterprise Development, Reservation Economic Summit is a four-day conference featuring training and business development opportunities, a tribal business leaders forum, a tradeshow and business expo featuring hundreds of exhibitors, and more!

  19. MEMORANDUM FO~~~ ATE DIRECTORS FROM:

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    If there are any questions, or further assistance is needed, please contact Daniel R. Lehman, Director, Office of Project Assessment (SC-28). Attachments cc: P. Dehmer, SC-2 G....

  20. Sensor System Fo4r Buried Waste Containment Sites

    DOE Patents [OSTI]

    Smith, Ann Marie; Gardner, Bradley M.; Kostelnik, Kevin M.; Partin, Judy K.; Lancaster, Gregory D.; Pfeifer, Mary Catherine

    2005-09-27

    A sensor system for a buried waste containment site having a bottom wall barrier and/or sidewall barriers, for containing hazardous waste. The sensor system includes one or more sensor devices disposed in one or more of the barriers for detecting a physical parameter either of the barrier itself or of the physical condition of the surrounding soils and buried waste, and for producing a signal representing the physical parameter detected. Also included is a signal processor for receiving signals produced by the sensor device and for developing information identifying the physical parameter detected, either for sounding an alarm, displaying a graphic representation of a physical parameter detected on a viewing screen and/or a hard copy printout. The sensor devices may be deployed in or adjacent the barriers at the same time the barriers are deployed and may be adapted to detect strain or cracking in the barriers, leakage of radiation through the barriers, the presence and leaking through the barriers of volatile organic compounds, or similar physical conditions.

  1. Sensor System Fo4r Buried Waste Containment Sites

    DOE Patents [OSTI]

    Smith, Ann Marie; Gardner, Bradley M.; Kostelnik, Kevin M.; Partin, Judy K.; Lancaster, Gregory D.; Pfeifer, Mary Catherine

    2003-11-18

    A sensor system for a buried waste containment site having a bottom wall barrier and sidewall barriers, for containing hazardous waste. The sensor system includes one or more sensor devices disposed in one or more of the barriers for detecting a physical parameter either of the barrier itself or of the physical condition of the surrounding soils and buried waste, and for producing a signal representing the physical parameter detected. Also included is a signal processor for receiving signals produced by the sensor device and for developing information identifying the physical parameter detected, either for sounding an alarm, displaying a graphic representation of a physical parameter detected on a viewing screen and/or a hard copy printout. The sensor devices may be deployed in or adjacent the barriers at the same time the barriers are deployed and may be adapted to detect strain or cracking in the barriers, leakage of radiation through the barriers, the presence and leaking through the barriers of volatile organic compounds, or similar physical conditions.

  2. Born on Pearl Harbor Day, and destined fo

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    on Pearl Harbor Day, and destined for a career in the Navy, Rear Admiral John Mitchell's early life was spent in West Texas and New Mexico. He graduated from Rice University in 1964 with degrees in math and electrical engineering and immediately entered the Navy through the Navy ROTC program. During his 30-year career in the Navy, Mitchell earned a master's degree in physics at the Naval Post Graduate School, served at sea and in shipyards, and spent 18 years in the Strategic Systems Program

  3. National RES Energy Track agenda

    Office of Environmental Management (EM)

    Featured Keynote Speaker Dr. Chris Emdin, Associate Professor in the Department of Mathematics, Science and Technology and Associate Director of the Institute for Urban and ...

  4. HPSS_Cover_Low_Res

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... Advanced Research Projects Agency (DARPA) Exascale Computing Study, Sep, 2008. 3 of ... These are derived from proposals of Extreme Scale architectures from the DARPA ExaScale ...

  5. TU-A-BRF-01: MR Guided Radiation Therapy

    SciTech Connect (OSTI)

    Stanescu, T; Balter, J; Nyholm, T; Lagendijk, J

    2014-06-15

    In recent years, there has been an increasing interest in the development of new technologies focused on the deeper integration of MR in radiotherapy. The innovations span from image data acquisition and post-processing to clinical implementation of MR-guided RT systems and workflow development. The session is intended to provide a review of the key and most recent advancements. Targeted discussions will cover topics which currently define the concept of MR-guided radiotherapy including a) system commissioning, quality control and safety, b) MR data manipulation for dose computations and treatment simulation, c) quantification/management of organ motion and treatment delivery guidance. Learning Objectives: Understand the concept and specifics of MR-guided radiotherapy; Understand the requirements for system integration in clinical workflow; Become familiar with the proposed strategies for system commissioning, RT planning and delivery guidance.

  6. TU-C-BRE-03: Aggregation of Linac Measurement Data

    SciTech Connect (OSTI)

    Kerns, J; Alvarez, P; Followill, D; Lowenstein, J; Molineu, A; Summers, P; Kry, S

    2014-06-15

    Purpose: Accurate data of linear accelerator radiation characteristics is important for treatment planning system commissioning as well as regular quality assurance of the machine. The RPC has performed site visits of numerous machines . Data gathered from Varian machines from the past 15 years are presented. The data collected can be used as a secondary check or when commissioning a new machine to verify that values are reasonable. Methods: Data from the past 15 years of RPC site visits was compiled and analyzed. Data was composed from measurements from approximately 400 Varian machines. Each dataset consists of several point measurements at various locations in a water phantom to measure percentage depth dose, output factors, including small MLC fields, off-axis factors, and wedge factors if applicable. Common statistical values are presented for each machine type. Where applicable, data was compared to other reference data given by the vendor or a select number of previous researchers. Results: Data is separated by energy and parameter and then analyzed by machine class. Data distributions of the parameter data were normal except occasionally at the tails. Distributions of the data for each class and parameter are tabulated to give not simply a singular reference value, but metrics about the distribution: 5th and 95th percentile values and the standard deviation as well as the median. Conclusion: The RPC has collected numerous data on Varian linacs and presented the finding of the past 15 years. The data can be used as a reference data set for physicists to compare against. A linac that deviates from the values does not necessarily indicate there is a problem as long as the treatment planning system correlates to the machine. Comparison of linac and treatment planning system data to external reference data can prevent serious treatment errors.

  7. Pl#xmam-*twe,m%-~h,i~tu.

    Office of Legacy Management (LM)

    bl 7-L c"v. tP cq 9hi 8 documen t? O?,?O sta 0f-A Je 4 %muw pace? and-.-G?-. fi::ur-e;. Q&LOPifx3, Series.... ' d o,.L Plxmam-*twe,m%-h,itu. vzP-1014uMalg* budi&&ah...

  8. RES Oklahoma 2016: DOE Business Opportunity Forum

    Broader source: Energy.gov [DOE]

    The U.S. Department of Energy (DOE) Office of Environmental Management (EM) is the second largest agency in federal government focused on the acquisition of goods and services. EM is responsible for the cleanup of the nation's Manhattan Project and Cold War defense nuclear legacy in a manner that is safe and protective to human health and environment.

  9. RES New Mexico 2016 | Department of Energy

    Energy Savers [EERE]

    Department of Energy RAMP Contractors Enforcement Letter, WEL-2014-03 - May 21, 2014 RAMP Contractors Enforcement Letter, WEL-2014-03 - May 21, 2014 May 21, 2014 Worker Safety and Health Enforcement Letter issued to Multiple National Nuclear Security Administration Contractors On May 21, 2014, the U.S. Department of Energy (DOE) Office of Independent Enterprise Assessment's Office of Enforcement issued an Enforcement Letter (WEL-2014-03) to Honeywell Federal Manufacturing & Technologies,

  10. Hi-Res WIPP onsite_offsite

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Information we have would indicate there is no offsite exposure risk The Radiological Release on Feb 14, 2014 13 Employees * Offsite sampling indicates radioactive levels only slightly above "background" at one location 0.6 miles from the site boundary. Background is defined as naturally-occurring radiation that is always present in our environment. * All indicators are that this was a one-time event. The event was detected by an underground continuous air monitor (CAM) that was in the

  11. Microsoft Word - winter.doc

    U.S. Energy Information Administration (EIA) Indexed Site

    0, 1998 http:www.eia.doe.gov A v e r a g e T e m p e r a tu r e fo r F o u r M a jo r G a s C o n s u m in g M e tr o A r e a s 0 1 0 2 0 3 0 4 0 5 0 6 0 7 0 8 0 1 0 1 9 8 1 0...

  12. APPLICATION FO FLOW FORMING FOR USE IN RADIOACTIVE MATERIAL PACKAGING DESIGNS

    SciTech Connect (OSTI)

    Blanton, P.; Eberl, K.; Abramczyk, G.

    2012-07-11

    This paper reports on the development and testing performed to demonstrate the use of flow forming as an alternate method of manufacturing containment vessels for use in radioactive material shipping packaging designs. Additionally, ASME Boiler and Pressure Vessel Code, Section III, Subsection NB compliance along with the benefits compared to typical welding of containment vessels will be discussed. SRNL has completed fabrication development and the testing on flow formed containment vessels to demonstrate the use of flow forming as an alternate method of manufacturing a welded 6-inch diameter containment vessel currently used in the 9975 and 9977 radioactive material shipping packaging. Material testing and nondestructive evaluation of the flow formed parts demonstrate compliance to the minimum material requirements specified in applicable parts of ASME Boiler and Pressure Vessel Code, Section II. Destructive burst testing shows comparable results to that of a welded design. The benefits of flow forming as compared to typical welding of containment vessels are significant: dimensional control is improved due to no weld distortion; less final machining; weld fit-up issues associated with pipes and pipe caps are eliminated; post-weld non-destructive testing (i.e., radiography and die penetrant tests) is not necessary; and less fabrication steps are required. Results presented in this paper indicate some of the benefits in adapting flow forming to design of future radioactive material shipping packages containment vessels.

  13. EP-AREAG-G-FO-DOP-124 Nitrate Salt Bearing TRU Waste Container Monitoring.pdf

    Office of Environmental Management (EM)

    Management (2007) | Department of Energy 423: Strengthening Federal Environmental, Energy, and Transportation Management (2007) EO 13423: Strengthening Federal Environmental, Energy, and Transportation Management (2007) It is the policy of the United States that Federal agencies conduct their environmental, transportation, and energy-related activities under the law in support of their respective missions in an environmentally, economically and fiscally sound, integrated, continuously

  14. Intial characterization fo a commerical electron gun for profiling high intensity proton beams in Project X

    SciTech Connect (OSTI)

    Thurman-Keup, R.; Johnson, A.S.; Lumpkin, A.H.; Thangaraj, J.C.T.; Zhang, D.; Blokland, W.; /Oak Ridge

    2011-03-01

    Measuring the profile of a high-intensity proton beam is problematic in that traditional invasive techniques such as flying wires don't survive the encounter with the beam. One alternative is the use of an electron beam as a probe of the charge distribution in the proton beam as was done at the Spallation Neutron Source at ORNL. Here we present an initial characterization of the beam from a commercial electron gun from Kimball Physics, intended for use in the Fermilab Main Injector for Project X. Despite the fact that the horizontal spot size is abnormally large in the high current measurement, the spot size at the downstream cross X2 is reasonable in the context of measuring the deflection. A thin foil OTR would help with the beam heating and should be tried. The next phase of this experiment is to simulate the proton beam with a pair of current carrying wires and to design and construct a fast deflector. Some of the remaining issues to be considered include determining the minimum beam current needed to observe the deflected beam for a given sweep time and the impact of longitudinal variations in the charge density of the bunch.

  15. http://www.blm.gov/nv/st/en/fo/lvfo/blm_programs/energy/propose

    National Nuclear Security Administration (NNSA)

    Key Observation Point Worksheets Appendix E - Conceptual Stormwater Control Plan part 1 Appendix E - Conceptual Stormwater Control Plan part 2 Appendix E - Conceptual Stormwater ...

  16. ITP Steel: Energy and Environmental Profile fo the U.S. Iron...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... Since 1970, the industry has invested more than 5 billion in air pollution control systems, much of it for particulate control. In a typical year, 15% of the industry's capital ...

  17. ITP Steel: Energy and Environmental Profile fo the U.S. Iron and Steel Industry

    Office of Energy Efficiency and Renewable Energy (EERE)

    DOE's Office of Industrial Technologes has formed a partnership with the U.S. iron and steel industry to accelerate development of technologies and processes that will improve the industry's production and energy efficiency and environmental performance.

  18. TU-C-12A-02: Development of a Multiparametric Statistical Response Map for Quantitative Imaging

    SciTech Connect (OSTI)

    Bosca, R; Mahajan, A; Brown, PD; Stafford, RJ; Johnson, VE; Dong, L; Jackson, EF

    2014-06-15

    Purpose: Quantitative imaging biomarkers (QIB) are becoming increasingly utilized in early phase clinical trials as a means of non-invasively assessing treatment response and associated response heterogeneity. The aim of this study was to develop a flexible multiparametric statistical framework to predict voxel-by-voxel response of several potential MRI QIBs. Methods: Patients with histologically proven glioblastomas (n=11) were treated with chemoradiation (with/without bevacizumab) and underwent one baseline and two mid-treatment (3–4wks) MRIs. Dynamic contrast-enhanced (3D FSPGR, 6.3sec/phase, 0.1 mmol/kg Gd-DTPA), dynamic susceptibility contrast (2D GRE-EPI, 1.5sec/phase, 0.2mmol/kg Gd-DTPA), and diffusion tensor (2D DW-EPI, b=0, 1200 s/mm{sup 2}, 27 directions) imaging acquisitions were obtained during each study. Mid-treatment and pre-treatment images were rigidly aligned, and regions of partial response (PR), stable disease (SD), and progressive disease (PD) were contoured in consensus by two experienced radiation oncologists. Voxels in these categories were used to train ordinal (PR

  19. TU-C-9A-01: IROC Organization and Clinical Trial Credentialing

    SciTech Connect (OSTI)

    Followill, D; Molineu, A; Xiao, Y

    2014-06-15

    As a response to recommendations from a report from the Institute of Medicine, NCI is reorganizing it clinical trial groups into a National Clinical Trial Network (NCTN) that consists of four adult groups (Alliance, ECOGACRIN, NRG, and SWOG) and one children’s group (COG). NRG will house CIRO, a center to promote innovative radiation therapy research and intergroup collaboration in radiation. The quality assurance groups that support clinical trials have also been restructured. ITC, OSU Imaging corelab, Philadelphia Imaging core-lab, QARC, RPC, and RTOGQA have joined together to create the Imaging and Radiation Oncology Core (IROC) Group. IROC’s mission is to provide integrated radiation oncology and diagnostic imaging quality control programs in support of the NCI’s NCTN thereby assuring high quality data for clinical trials designed to improve the clinical outcomes for cancer patients worldwide. This will be accomplished through five core services: site qualification, trial design support, credentialing, data management, case review.These changes are important for physicist participating in NCI clinical trials to understand. We will describe in detail the IROC’s activities and five core services so that as a user, the medical physicist can learn how to efficiently utilize this group. We will describe common pitfalls encountered in credentialing for current protocols and present methods to avoid them. These may include the which benchmarks are required for NSABP B-51/RTOG 1304 and how to plan them as well as tips for phantom planning. We will explain how to submit patient and phantom cases in the TRIAD system used by IROC. Learning Objectives: To understand the basic organization of IROC, its mission and five core services To learn how to use TRIAD for patient and phantom data submission To learn how to avoid common pitfalls in credentialing for current trials.

  20. TU-F-17A-07: Real-Time Personalized Margins

    SciTech Connect (OSTI)

    Rottmann, J; Berbeco, R

    2014-06-15

    Purpose: To maximize normal tissue sparing for treatments requiring motion encompassing margins. Motion mitigation techniques including DMLC or couch tracking can freeze tumor motion within the treatment aperture potentially allowing for smaller treatment margins and thus better sparing of normal tissue. To enable for a safe application of this concept in the clinic we propose adapting margins dynamically in real-time during radiotherapy delivery based on personalized tumor localization confidence. To demonstrate technical feasibility we present a phantom study. Methods: We utilize a realistic anthropomorphic dynamic thorax phantom with a lung tumor model embedded close to the spine. The tumor, a 3D-printout of a patient's GTV, is moved 15mm peak-to-peak by diaphragm compression and monitored by continuous EPID imaging in real-time. Two treatment apertures are created for each beam, one representing ITV -based and the other GTV-based margin expansion. A soft tissue localization (STiL) algorithm utilizing the continuous EPID images is employed to freeze tumor motion within the treatment aperture by means of DMLC tracking. Depending on a tracking confidence measure (TCM), the treatment aperture is adjusted between the ITV and the GTV leaf. Results: We successfully demonstrate real-time personalized margin adjustment in a phantom study. We measured a system latency of about 250 ms which we compensated by utilizing a respiratory motion prediction algorithm (ridge regression). With prediction in place we observe tracking accuracies better than 1mm. For TCM=0 (as during startup) an ITV-based treatment aperture is chosen, for TCM=1 a GTV-based aperture and for 0

  1. TU-D-9A-01: TG176: Dosimetric Effects of Couch Tops and Immobilization Devices

    SciTech Connect (OSTI)

    Olch, A

    2014-06-15

    The dosimetric impact from devices external to the patient is a complex combination of increased skin dose, reduced tumor dose, and altered dose distribution. Although small monitor unit or dose corrections are routinely made for blocking trays, ion chamber correction factors, or tissue inhomogeneities, the dose perturbation of the treatment couch top or immobilization devices are often overlooked. These devices also increase surface dose, an effect which is also often ignored or underestimated. These concerns have grown recently due to the increased use of monolithic carbon fiber couch tops which are optimal for imaging for patient position verification but cause attenuation and increased surface dose compared to the ‘tennis racket’ style couch top they often replace. Also, arc delivery techniques have replaced stationary gantry techniques which cause a greater fraction of the dose to be delivered from posterior angles. A host of immobilization devices are available and used to increase patient positioning reproducibility, and these also have attenuation and skin dose implications which are often ignored. This report of Task Group 176 serves to present a survey of published data that illustrates the magnitude of the dosimetric effects of a wide range of devices external to the patient. The report also provides methods for modeling couch tops in treatment planning systems so the physicist can accurately compute the dosimetric effects for indexed patient treatments. Both photon and proton beams are considered. A discussion on avoidance of high density structures during beam planning is also provided. An important aspect of this report are the recommendations we make to clinical physicists, treatment planning system vendors, and device vendors on how to make measurements of skin dose and attenuation, how to report these values, and for the vendors, an appeal is made to work together to provide accurate couch top models in planning systems. Learning Objectives: What are the dosimetric effects of couch tops What are the dosimetric effects of immobilization devices How can one model couch tops in the treatment planning system How can one measure attenuation and surface dose changes due to external devices.

  2. TU-F-9A-01: Balancing Image Quality and Dose in Radiography

    SciTech Connect (OSTI)

    Peck, D; Pasciak, A

    2014-06-15

    Emphasis is often placed on minimizing radiation dose in diagnostic imaging without a complete consideration of the effect on image quality, especially those that affect diagnostic accuracy. This session will include a patient image-based review of diagnostic quantities important to radiologists in conventional radiography, including the effects of body habitus, age, positioning, and the clinical indication of the exam. The relationships between image quality, radiation dose, and radiation risk will be discussed, specifically addressing how these factors are affected by image protocols and acquisition parameters and techniques. This session will also discuss some of the actual and perceived radiation risk associated with diagnostic imaging. Regardless if the probability for radiation-induced cancer is small, the fear associated with radiation persists. Also when a risk has a benefit to an individual or to society, the risk may be justified with respect to the benefit. But how do you convey the risks and the benefits to people? This requires knowledge of how people perceive risk and how to communicate the risk and the benefit to different populations. In this presentation the sources of errors in estimating risk from radiation and some methods used to convey risks are reviewed. Learning Objectives: Understand the image quality metrics that are clinically relevant to radiologists. Understand how acquisition parameters and techniques affect image quality and radiation dose in conventional radiology. Understand the uncertainties in estimates of radiation risk from imaging exams. Learn some methods for effectively communicating radiation risk to the public.

  3. TU-F-18C-07: Hardware Advances for MTF Improvement in Dedicated Breast CT

    SciTech Connect (OSTI)

    Gazi, P; Burkett, G; Yang, K; Boone, J

    2014-06-15

    Purpose: In this study, we have designed and implemented a prototype dedicated breast CT system (bCT) to improve the spatial resolution characteristics, in order to improve detection of micro-calcifications. Methods: A 10.8 kW water-cooled, tungsten anode x-ray tube, running up to 240 mA at 60 kV, coupled with an x-ray generator specifically designed for this application, and 0.3 mm of added copper filter was used to generate x-ray pulses. A CsI CMOS flat panel detector with a pixel pitch of 0.075 mm in native binning mode was used. The system geometry was designed in a way to achieve an FOV on par with similar bCT prototypes, resulting in a magnification factor of 1.39. A 0.013 mm tungsten wire was used to generate point spread functions. Multiple scans were performed with different numbers of projections, different reconstruction kernel sizes and different reconstruction filters to study the effects of each parameter on MTF. The resulting MTFs were then evaluated quantitatively using the generated PFSs. Duplicate scans with the same parameters were performed on two other dedicated breast CT systems to compare the performance of the new prototype. Results: The results of the MTF experiments demonstrate a significant improvement in the spatial resolution characteristics. In the new prototype, using the pulsed x-ray source results in a restoration of the azimuthal MTF degradation, due to motion blurring previously seen in other bCT systems. Moreover, employing the higher resolution x-ray detector considerably improves the MTF. The MTF at 10% of the new system is at 3.5 1/mm, a factor of 4.36 greater than an earlier bCT scanner. Conclusion: The MTF analysis of the new prototype bCT shows that using the new hardware and control results in a significant improvement in visualization of finer detail. This suggests that the visualization of micro-calcifications will be significantly improved.

  4. TU-C-BRF-01: Innovation in Medical Physics and Engineering

    SciTech Connect (OSTI)

    Mohan, R; Pelc, N; Jaffray, D; Mackie, T

    2014-06-15

    We seek to heighten the awareness of the role of research and innovation that leads to clinical advances in the field of medical physics and engineering. Marie Curie (discovery and use of radium) and Harold Johns (Co-60 tele-therapy) in radiotherapy, and pioneers in imaging (Allan Cormack and Godfrey Hounsfield for the CT and Paul Lauterbur, Peter Mansfield for MRI, etc.) were scientists often struggling against great odds. Examples of more recent innovations that are clearly benefitting our patients include IMRT, Image Guided Radiation Therapy and Surgery, Particle Therapy, Quantitative imaging, amongst others.We would also like to highlight the fact that not all of the discovery and engineering that we benefit from in today’s world, was performed at research institutions alone. Rather, companies often tread new ground at financial and reputational risk. Indeed the strength of the private sector is needed in order to bring about new advances to our practice. The keys to long term success in research and development may very well include more public and private research spending. But, when more investigators are funded, we also need to recognize that there needs to be a willingness on the part of the funding institutions, academic centers and investigators to risk failure for the greater potential achievements in innovation and research. The speakers will provide examples and insight into the fields of innovation and research in medical physics from their own first hand experiences. Learning Objectives: To obtain an understanding of the importance of research and development towards advances in physics in medicine. To raise awareness of the role of interdisciplinary collaborations in translational research and innovation. To highlight the importance of entrepreneurships and industrial-institutional research partnerships in fostering new ideas and their commercial success. To recognize and account for the risk of failure for the greater potential achievements in innovation and research.

  5. TU-C-17A-05: Dose Domain Optimization of MLC Leaf Patterns for...

    Office of Scientific and Technical Information (OSTI)

    domain required multiplying the fluence with a sparse matrix. Exploiting this property made it feasible to solve the problem using CVX, a MATLAB-based convex modeling framework. ...

  6. TU-C-BRE-10: A Streamlined Approach to EPID Transit Dosimetry

    SciTech Connect (OSTI)

    Morris, B; Fontenot, J

    2014-06-15

    Purpose: To investigate the feasibility of a simple and efficient transit dosimetry method using the electronic portal imaging device (EPID) for dose delivery error detection and prevention. Methods: In the proposed method, 2D reference transit images are generated for comparison with online images acquired during treatment. Reference transit images are generated by convolving through-air EPID measurements of each field with pixel-specific kernels selected from a library of pre-calculated Monte Carlo pencil kernels of varying radiological thickness. The kernel used for each pixel is selected based on the calculated radiological thickness of the patient along a line joining the pixel and the virtual source. The accuracy of the technique was evaluated in flat homogeneous and heterogeneous plastic water phantoms, a heterogeneous cylindrical phantom, and an anthropomorphic head phantom. Gamma criteria of 3%/3 mm was used to quantify the accuracy of the technique for the various cases. Results: An average of 99.9% and 99.7% of the points in the comparison between the measured and predicted images passed a 3%/3mm gamma for the homogeneous and heterogeneous plastic water phantoms, respectively. 97.1% of the points passed for the analysis of the heterogeneous cylindrical phantom. For the anthropomorphic head phantom, an average of 97.8% of points passed the 3%/3mm gamma criteria for all field sizes. Failures were observed primarily in areas of drastic thickness or material changes and at the edges of the fields. Conclusion: The data suggest that the proposed transit dosimetry method is a feasible approach to in vivo dose monitoring. Future research efforts could include implementation for more complex fields and sensitivity testing of the method to setup errors and changes in anatomy. Oncology Data Systems provided partial funding support but did not participate in the collection or analysis of data.

  7. TU-C-BRE-09: Performance Comparisons of Patient Specific IMRT QA Methodologies Using ROC Analysis

    SciTech Connect (OSTI)

    McKenzie, E; Balter, P; Stingo, F; Followill, D; Kry, S; Jones, J

    2014-06-15

    Purpose: To evaluate the ability of a selection of patient-specific QA methods to accurately classify IMRT plans as acceptable or unacceptable based on a multiple ion chamber (MIC) phantom. Methods: Twenty-four IMRT plans were selected (20 previously failed the institutional QA), and were measured on a MIC phantom to assess their dosimetric acceptability. These same plans were then measured using film (Kodak EDR2) and ion chamber (Wellhofer cc04), ArcCheck (Sun Nuclear), and MapCheck (Sun Nuclear) (delivered AP field-by-field, AP composite, and with original gantry angles). All gamma analyses were performed at 2%/2mm, 3%/3mm, and 5%/3mm. By using the MIC results as a gold standard, the sensitivity and specificity were calculated across a range of cut-off thresholds (% pixels passing for gamma analysis, and % dose difference for ion chamber), and were used to form ROC curves. Area under the curve (AUC) was used as a metric to quantify the performance of the various QA methods. Results: Grouping devices AUCs revealed two statistically significant different groups: ion chamber (AUC of 0.94), AP composite MapCheck (AUC of 0.85), ArcCheck (AUC of 0.84), and film (AUC of 0.82) were in the better performing group, while original gantry angles and AP field-by-field MapCheck (AUC of 0.65 and 0.66, respectively) matched less well with the gold standard results. Optimal cut-offs were also assessed using the ROC curves. We found that while often 90% of pixels passing is used as a criteria, the differing sensitivities of QA methods can lead to device and methodology-based optimal cutoff thresholds. Conclusion: While many methods exist to perform the same task of patient-specific IMRT QA, they utilize different strategies. This work has shown that there are inconsistencies in these methodologies in terms of their sensitivity and specificity to dosimetric acceptability. This work was supported by Public Health Service grants CA010953, CA081647, and CA21661 awarded by the National Cancer Institute, United States Department of Health and Human Services.

  8. TU-B-19A-01: Image Registration II: TG132-Quality Assurance for Image Registration

    SciTech Connect (OSTI)

    Brock, K; Mutic, S

    2014-06-15

    AAPM Task Group 132 was charged with a review of the current approaches and solutions for image registration in radiotherapy and to provide recommendations for quality assurance and quality control of these clinical processes. As the results of image registration are always used as the input of another process for planning or delivery, it is important for the user to understand and document the uncertainty associate with the algorithm in general and the Result of a specific registration. The recommendations of this task group, which at the time of abstract submission are currently being reviewed by the AAPM, include the following components. The user should understand the basic image registration techniques and methods of visualizing image fusion. The disclosure of basic components of the image registration by commercial vendors is critical in this respect. The physicists should perform end-to-end tests of imaging, registration, and planning/treatment systems if image registration is performed on a stand-alone system. A comprehensive commissioning process should be performed and documented by the physicist prior to clinical use of the system. As documentation is important to the safe implementation of this process, a request and report system should be integrated into the clinical workflow. Finally, a patient specific QA practice should be established for efficient evaluation of image registration results. The implementation of these recommendations will be described and illustrated during this educational session. Learning Objectives: Highlight the importance of understanding the image registration techniques used in their clinic. Describe the end-to-end tests needed for stand-alone registration systems. Illustrate a comprehensive commissioning program using both phantom data and clinical images. Describe a request and report system to ensure communication and documentation. Demonstrate an clinically-efficient patient QA practice for efficient evaluation of image registration.

  9. TU-D-BRD-01: Image Guided SBRT II: Challenges ' Pitfalls

    SciTech Connect (OSTI)

    Chang, Z; Yin, F; Cho, J

    2014-06-15

    Stereotactic body radiation therapy (SBRT) has been effective treatment for the management of various diseases, which often delivers high radiation dose in a single or a few fractions. SBRT therefore demands precise treatment delivery to the tumor while sparing adjacent healthy tissue. Recent developments in image guidance enable target localization with increased accuracy. With such improvements in localization, image-guided SBRT has been widely adopted into clinical practice. In SBRT, high radiation dose is generally delivered with small fields. Therefore, it is crucial to accurately measure dosimetric data for the small fields during commissioning. In addition, image-guided SBRT demands accurate image localization to ensure safety and quality of patient care. Lately, the reports of AAPM TG 142 and TG 104 have been published and added recommendations for imaging devices that are integrated with the linear accelerator for SBRT. Furthermore, various challenges and potential pitfalls lie in the clinical implementation of image-guided SBRT. In this lecture, these challenges and pitfalls of image-guided SBRT will be illustrated and discussed from dosimetric, technical and clinical perspectives.Being a promising technique, image-guided SBRT has shown great potentials, and will lead to more accurate and safer SBRT treatments. Learning Objectives: To understand dosimetric challenges and pitfalls for IGRT application in SBRT. To understand major clinical challenges and pitfalls for IGRT application in SBRT. To understand major technical challenges and pitfalls for IGRT application in SBRT.

  10. TU-A-18C-01: ACR Accreditation Updates in CT, Ultrasound, Mammography and MRI

    SciTech Connect (OSTI)

    Price, R; Berns, E; Hangiandreou, N; McNitt-Gray, M

    2014-06-15

    A goal of an imaging accreditation program is to ensure adequate image quality, verify appropriate staff qualifications, and to assure patient and personnel safety. Currently, more than 35,000 facilities in 10 modalities have been accredited by the American College of Radiology (ACR), making the ACR program one of the most prolific accreditation options in the U.S. In addition, the ACR is one of the accepted accreditations required by some state laws, CMS/MIPPA insurance and others. Familiarity with the ACR accreditation process is therefore essential to clinical diagnostic medical physicists. Maintaining sufficient knowledge of the ACR program must include keeping up-to-date as the various modality requirements are refined to better serve the goals of the program and to accommodate newer technologies and practices. This session consists of presentations from authorities in four ACR accreditation modality programs, including magnetic resonance imaging, mammography, ultrasound, and computed tomography. Each speaker will discuss the general components of the modality program and address any recent changes to the requirements. Learning Objectives: To understand the requirements of the ACR MR accreditation program. The discussion will include accreditation of whole-body general purpose magnets, dedicated extremity systems well as breast MRI accreditation. Anticipated updates to the ACR MRI Quality Control Manual will also be reviewed. To understand the current ACR MAP Accreditation requirement and present the concepts and structure of the forthcoming ACR Digital Mammography QC Manual and Program. To understand the new requirements of the ACR ultrasound accreditation program, and roles the physicist can play in annual equipment surveys and setting up and supervising the routine QC program. To understand the requirements of the ACR CT accreditation program, including updates to the QC manual as well as updates through the FAQ process.

  11. TU-PIS-Exhibit Hall-01: CT Dose Optimization Technologies II

    SciTech Connect (OSTI)

    Driesser, I; Angel, E

    2014-06-15

    Partners in Solutions is an exciting new program in which AAPM partners with our vendors to present practical “hands-on” information about the equipment and software systems that we use in our clinics. The imaging topic this year is CT scanner dose optimization capabilities. Note that the sessions are being held in a special purpose room built on the Exhibit Hall Floor, to encourage further interaction with the vendors. Siemens‘ Commitment to the Right Dose in Computed Tomography Presentation Time: 11:15 - 11:45 AM Providing sustainable clinical results at highest patient safety: This is the challenge in medical imaging. Especially for Computed Tomography this means applying not simply the lowest, but the right dose for sound diagnostic imaging. Consequently, Siemens is committed to deliver the right dose in CT. In order to reduce radiation to the right dose, the first step is to provide the right dose technology. Through decades of research and development in CT imaging, Siemens CT has constantly introduced new ideas leading to a comprehensive portfolio of unique CARE technologies to deliver the right dose. For example automated kV adjustment based on patient size and the clinical question with CARE kV and three generations of iterative reconstruction. Based on the right dose technology, the next step is to actually scan at the right dose. For this, it is key to know the right dose targets for every examination. Siemens continuously involves CT experts to push developments further and outline how users can best adapt their procedures to the right dose. For users to know whether they met the right dose targets, it is therefore important to understand and monitor the actual absolute dose values. All scanners are delivered with defined default protocols which automatically use the available right dose technologies. Finally, to deliver the right dose not just in singular cases, but ideally to patients everywhere, organizations need then to manage dose across their institutions. Here Siemens offers the right dose management tools for administrations to analyze and document dose, to train their clinical staff and to continuously optimize the application of the right dose in clinical routine. Siemens CT is not only adhering to the ALARA principle, but is inspired by it. With CARE Right Siemens show their commitment to the right dose in CT. Toshiba Aquilion CT Dose Management Tools Presentation Time: 11:45 - 12:15 PM A practical review of Toshiba’s CT dose management technologies from the physicist’s perspective. This presentation will include an overview of Toshiba’s CT dose reduction technologies and dose safeguards. Content will include answers to frequently asked questions relating to dose management, dose tracking, CTDI measurement, ACR accreditation, ACR QC, and protocol review on Toshiba CT systems. Specific topics will include the following: Toshiba’s mechanism of tube current modulation; Exposure record format and interpretation of the values; Dose reporting and dose safeguard tools; Use of AIDR 3D iterative reconstruction; The configuration of task specific image quality target and its integration with AIDR 3D; Tips for scanning the ACR phantom with wide beam geometry; Measuring CTDI for wide beam geometry; Discussion of daily QC procedures and specifications; Tips for annual QC evaluation; Protocol management tools.

  12. TU-F-18A-02: Iterative Image-Domain Decomposition for Dual-Energy CT

    SciTech Connect (OSTI)

    Niu, T; Dong, X; Petrongolo, M; Zhu, L

    2014-06-15

    Purpose: Dual energy CT (DECT) imaging plays an important role in advanced imaging applications due to its material decomposition capability. Direct decomposition via matrix inversion suffers from significant degradation of image signal-to-noise ratios, which reduces clinical value. Existing de-noising algorithms achieve suboptimal performance since they suppress image noise either before or after the decomposition and do not fully explore the noise statistical properties of the decomposition process. We propose an iterative image-domain decomposition method for noise suppression in DECT, using the full variance-covariance matrix of the decomposed images. Methods: The proposed algorithm is formulated in the form of least-square estimation with smoothness regularization. It includes the inverse of the estimated variance-covariance matrix of the decomposed images as the penalty weight in the least-square term. Performance is evaluated using an evaluation phantom (Catphan 600) and an anthropomorphic head phantom. Results are compared to those generated using direct matrix inversion with no noise suppression, a de-noising method applied on the decomposed images, and an existing algorithm with similar formulation but with an edge-preserving regularization term. Results: On the Catphan phantom, our method retains the same spatial resolution as the CT images before decomposition while reducing the noise standard deviation of decomposed images by over 98%. The other methods either degrade spatial resolution or achieve less low-contrast detectability. Also, our method yields lower electron density measurement error than direct matrix inversion and reduces error variation by over 97%. On the head phantom, it reduces the noise standard deviation of decomposed images by over 97% without blurring the sinus structures. Conclusion: We propose an iterative image-domain decomposition method for DECT. The method combines noise suppression and material decomposition into an iterative process and achieves both goals simultaneously. The proposed algorithm shows superior performance on noise suppression with high image spatial resolution and low-contrast detectability. This work is supported by a Varian MRA grant.

  13. Property:Incentive/ResCode | Open Energy Information

    Open Energy Info (EERE)

    mandatory statewide. Buildings must also meet requirements set by CALGreen, the statewide green building code. Building Energy Code (Colorado) + 2003 IECC or any successor edition...

  14. UTILITYID","UTILNAME","STATE","YEAR","MONTH","RES_REV (Thousand...

    U.S. Energy Information Administration (EIA) Indexed Site

    ...140,3411,8263,101101,76731 12919,"Morenci Water and Electric Co","AZ",2002,1,99,893,1677,1... 17612,"Southern California Water Co","CA",2002,1,981,7522,20261,699,4602,14...

  15. Cal. Pub. Res. Code 6009 | Open Energy Information

    Open Energy Info (EERE)

    Code 6009Legal Abstract Statutory section containing general provisions for administration and control of state lands in California. Published NA Year Signed or Took Effect...

  16. Add RES 2016 Energy Track Sessions to Your Calendar

    Broader source: Energy.gov [DOE]

    Download calendar invitations for the four energy track sessions being hosted by the Department of Energy Office of Indian Energy at the 2016 National Reservation Economic Summit.

  17. UTILITY_ID","UTILNAME","STATE_CODE","YEAR","MONTH","RES_REV ...

    U.S. Energy Information Administration (EIA) Indexed Site

    ...,36821,36,0,0,0,26141,213643,157797 7601,"Green Mountain Power Corp","VT",2008,1,8988,6341....914,413072.399,125374 15500,"Puget Sound Energy Inc","WA",2008,1,121907,1271939,934919,70...

  18. Microsoft PowerPoint - NanoRes_Sumpter_2013.pptx

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    material semiconducting, while an uniaxial strain varying from compressive to tensile causes the spin-resolved selective self-doping to increase the half-metallic character of the...

  19. Property:Incentive/WindResPercMax | Open Energy Information

    Open Energy Info (EERE)

    I Independence Light & Power - Renewable Energy Rebates (Iowa) + 25% + L Local Small Wind Rebate Programs (Colorado) + 50% + M Maquoketa Municipal Electric Utility - Renewable...

  20. PrintRes_PeriodicChartPostCard2014

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    0 Hg Mercury 35 Br Bromine 43 c echnetium 93 Np Neptunium 94 Pu Plutonium 95 Am Americium 96 Cm Curium 97 Bk Berkelium 98 Cf Californium 99 Es Einsteinium 100 Fm Fermium 101 Md Mendelevium 102 No Nobelium 105 107 106 108 109 111 110 112 Db Dubnium Sg Hs Hassium Bh Seaborgium Bohrium Mt Meitnerium Uun Ununnilium Uuu Unununium 114 116 103 Lr Lawrencium 104 Rf Rutherfordium Uub Ununbium Uuq Ununquadium Uuh Ununhexium T T 17 Cl Chlorine 18 Ar Argon 1 H Hydrogen 86 Rn Radon 10 Ne Neon 2 He Helium 9 O

  1. UTILITYID","UTILNAME","STATE","YEAR","MONTH","RES_REV (Thousand...

    U.S. Energy Information Administration (EIA) Indexed Site

    ...3087,1030,13416,78902,1093643 230,"Albany Water Gas & Light Comm","GA",91,1,1909,28956,203...6,11,146,0,0,0,0,52,672 20169,"Washington Water Power Co","ID",91,1,5783,115951,3076,59228...

  2. UTILITYID","UTILNAME","STATE","YEAR","MONTH","RES_REV (Thousand...

    U.S. Energy Information Administration (EIA) Indexed Site

    ... Coop., Inc.","ID",1998,1,157,2936,79,1673,512,15956,2,27,750,20592 20169,"Washington Water ... 10704,"Lansing Board of Water & Light","MI",1998,1,3260,53666,4999,92086...

  3. UTILITYID","UTILNAME","STATE","YEAR","MONTH","RES_REV (Thousand...

    U.S. Energy Information Administration (EIA) Indexed Site

    ...813,3227,8615,104522,78221 12919,"Morenci Water and Electric Co","AZ",2003,1,84,861,1629,1... 17612,"Southern California Water Co","CA",2003,1,1348,7113,22065,887,4275,1...

  4. UTILITYID","UTILNAME","STATE","YEAR","MONTH","RES_REV (Thousand...

    U.S. Energy Information Administration (EIA) Indexed Site

    ...954,1069,7452,101834,72474 12919,"Morenci Water and Electric Co","AZ",2001,1,117,1024,1844... 17612,"Southern California Water Co.","CA",2001,1,725,7169,20074,619,5098,1...

  5. UTILITYID","UTILNAME","STATE","YEAR","MONTH","RES_REV (Thousand...

    U.S. Energy Information Administration (EIA) Indexed Site

    ...,0,0,134364,1865437,958837 12919,"Morenci Water and Electric Co","AZ",2004,1,104,937,1633,... 17612,"Southern California Water Co","CA",2004,1,1411,7412,20754,873,4273,1...

  6. UTILITY_ID","UTILNAME","STATE_CODE","YEAR","MONTH","RES_REV ...

    U.S. Energy Information Administration (EIA) Indexed Site

    ...0,0,183241,2189905,1081602 12919,"Morenci Water and Electric","AZ","2007R",1,154,1330,1816... 17612,"Southern California Water Co","CA","2007R",1,1831,8334,21746,1030,47...

  7. UTILITYID","UTILNAME","STATE","YEAR","MONTH","RES_REV (Thousand...

    U.S. Energy Information Administration (EIA) Indexed Site

    ...5814,1109,14163,81951,1135561 230,"Albany Water Gas & Light Comm","GA",92,1,2125,31241,213...1427,31,263,9507,257389 20169,"Washington Water Power Co","ID",92,1,4742,98397,3078,60320,...

  8. UTILITYID","UTILNAME","STATE","YEAR","MONTH","RES_REV (Thousand...

    U.S. Energy Information Administration (EIA) Indexed Site

    ...5052,27,251,8944,238616 20169,"Washington Water Power Co","ID",95,1,5682,111117,3920,72853... 10704,"Lansing Board of Water & Light","MI",95,1,3112,52319,4624,85152,2...

  9. UTILITYID","UTILNAME","STATE","YEAR","MONTH","RES_REV (Thousand...

    U.S. Energy Information Administration (EIA) Indexed Site

    ...22,19981,3,27,981,24477 20169,"Washington Water Power Co","ID",96,1,6556,125105,4575,80600... 10704,"Lansing Board of Water & Light","MI",96,1,3279,55206,4919,90320,2...

  10. UTILITY_ID","UTILNAME","STATE_CODE","YEAR","MONTH","RES_REV ...

    U.S. Energy Information Administration (EIA) Indexed Site

    ...0,0,152914,1973624,1040286 12919,"Morenci Water and Electric","AZ",2006,1,113,1023,1765,14... 17612,"Southern California Water Co","CA",2006,1,1816,8220,21451,957,4369,1...

  11. UTILITYID","UTILNAME","STATE","YEAR","MONTH","RES_REV (Thousand...

    U.S. Energy Information Administration (EIA) Indexed Site

    ...3,26,238,584,17460,2567 20169,"Washington Water Power Company","ID",2000,1,5585,114234,883... 10704,"Lansing Board of Water & Light","MI",2000,1,3381,55779,80732,5153...

  12. UTILITYID","UTILNAME","STATE","YEAR","MONTH","RES_REV (Thousand...

    U.S. Energy Information Administration (EIA) Indexed Site

    ...435,30,253,10714,270237 20169,"Washington Water Power Co","ID",93,1,5856,113174,3343,60803... 10704,"Lansing Board of Water & Light","MI",93,1,2886,51178,4048,79470,2...

  13. UTILITYID","UTILNAME","STATE","YEAR","MONTH","RES_REV (Thousand...

    U.S. Energy Information Administration (EIA) Indexed Site

    ...9986,3201,48196,77291,1148551 230,"Albany Water Gas & Light Comm","GA",90,1,2235,35967,202...44,4,42,6,83,0,7,39,476 20169,"Washington Water Power Co","ID",90,1,4634,93527,2862,53688,...

  14. UTILITYID","UTILNAME","STATE","YEAR","MONTH","RES_REV (Thousand...

    U.S. Energy Information Administration (EIA) Indexed Site

    ...3,28,235,551,16140,2505 20169,"Washington Water Power Company","ID",1999,1,5750,115046,852... 10704,"Lansing Board of Water & Light","MI",1999,1,3395,56092,80316,5030...

  15. UTILITYID","UTILNAME","STATE","YEAR","MONTH","RES_REV (Thousand...

    U.S. Energy Information Administration (EIA) Indexed Site

    ...6491,28,247,9775,248573 20169,"Washington Water Power Co","ID",94,1,4850,97496,3528,66911,... 10704,"Lansing Board of Water & Light","MI",94,1,3136,54753,4476,85147,2...

  16. UTILITYID","UTILNAME","STATE","YEAR","MONTH","RES_REV (Thousand...

    U.S. Energy Information Administration (EIA) Indexed Site

    ...8,,,,144250,1967403,997211 12919,"Morenci Water and Electric Co","AZ",2005,1,104,937,1633,... 17612,"Southern California Water Co","CA",2005,1,1640,8633,21194,1020,4871,...

  17. UTILITYID","UTILNAME","STATE","YEAR","MONTH","RES_REV (Thousand...

    U.S. Energy Information Administration (EIA) Indexed Site

    ...15,19431,3,27,878,23985 20169,"Washington Water Power Co","ID",97,1,7113,141994,4397,83795... 10704,"Lansing Board of Water & Light","MI",97,1,3369,55053,4969,88917,2...

  18. Site characterization plan: Conceptual design report: Volume 4, Appendices F-O: Nevada Nuclear Waste Storage Investigations Project

    SciTech Connect (OSTI)

    MacDougall, H R; Scully, L W; Tillerson, J R

    1987-09-01

    The site for the prospective repository is located at Yucca Mountain in southwestern Nevada, and the waste emplacement area will be constructed in the underlying volcanic tuffs. The target horizon for waste emplacement is a sloping bed of densely welded tuff more than 650 ft below the surface and typically more than 600 ft above the water table. The conceptual design described in this report is unique among repository designs in that it uses ramps in addition to shafts to gain access to the underground facility, the emplacement horizon is located above the water table, and it is possible that 300- to 400-ft-long horizontal waste emplacement boreholes will be used. This report summarizes the design bases, design and performance criteria, and the design analyses performed. The current status of meeting the preclosure performance objectives for licensing and of resolving the repository design and preclosure issues is presented. The repository design presented in this report will be expanded and refined during the advanced conceptual design, the license application design, and the final procurement and construction design phases. Volume 4 contains Appendices F to O.

  19. TU-F-18A-09: CT Number Stability Across Patient Sizes Using Virtual-Monoenergetic Dual-Energy CT

    SciTech Connect (OSTI)

    Michalak, G; Grimes, J; Fletcher, J; McCollough, C; Halaweish, A

    2014-06-15

    Purpose: Virtual-monoenergetic imaging uses dual-energy CT data to synthesize images corresponding to a single photon energy, thereby reducing beam-hardening artifacts. This work evaluated the ability of a commercial virtual-monoenergetic algorithm to achieve stable CT numbers across patient sizes. Methods: Test objects containing a range of iodine and calcium hydroxyapatite concentrations were placed inside 8 torso-shaped water phantoms, ranging in lateral width from 15 to 50 cm, and scanned on a dual-source CT system (Siemens Somatom Force). Single-energy scans were acquired from 70-150 kV in 10 kV increments; dual-energy scans were acquired using 4 energy pairs (low energy: 70, 80, 90, and 100 kV; high energy: 150 kV + 0.6 mm Sn). CTDIvol was matched for all single- and dual-energy scans for a given phantom size. All scans used 128×0.6 mm collimation and were reconstructed with 1-mm thickness at 0.8-mm increment and a medium smooth body kernel. Monoenergetic images were generated using commercial software (syngo Via Dual Energy, VA30). Iodine contrast was calculated as the difference in mean iodine and water CT numbers from respective regions-of-interest in 10 consecutive images. Results: CT numbers remained stable as phantom width varied from 15 to 50 cm for all dual-energy data sets (except for at 50 cm using 70/150Sn due to photon starvation effects). Relative to the 15 cm phantom, iodine contrast was within 5.2% of the 70 keV value for phantom sizes up to 45 cm. At 90/150Sn, photon starvation did not occur at 50 cm, and iodine contrast in the 50-cm phantom was within 1.4% of the 15-cm phantom. Conclusion: Monoenergetic imaging, as implemented in the evaluated commercial system, eliminated the variation in CT numbers due to patient size, and may provide more accurate data for quantitative tasks, including radiation therapy treatment planning. Siemens Healthcare.

  20. TU-F-18A-03: Improving Tissue Segmentation for Monte Carlo Dose Calculation Using DECT Data

    SciTech Connect (OSTI)

    Di, Salvio A; Bedwani, S; Carrier, J

    2014-06-15

    Purpose: To develop a new segmentation technique using dual energy CT (DECT) to overcome limitations related to segmentation from a standard Hounsfield unit (HU) to electron density (ED) calibration curve. Both methods are compared with a Monte Carlo analysis of dose distribution. Methods: DECT allows a direct calculation of both ED and effective atomic number (EAN) within a given voxel. The EAN is here defined as a function of the total electron cross-section of a medium. These values can be effectively acquired using a calibrated method from scans at two different energies. A prior stoichiometric calibration on a Gammex RMI phantom allows us to find the parameters to calculate EAN and ED within a voxel. Scans from a Siemens SOMATOM Definition Flash dual source system provided the data for our study. A Monte Carlo analysis compares dose distribution simulated by dosxyz-nrc, considering a head phantom defined by both segmentation techniques. Results: Results from depth dose and dose profile calculations show that materials with different atomic compositions but similar EAN present differences of less than 1%. Therefore, it is possible to define a short list of basis materials from which density can be adapted to imitate interaction behavior of any tissue. Comparison of the dose distributions on both segmentations shows a difference of 50% in dose in areas surrounding bone at low energy. Conclusion: The presented segmentation technique allows a more accurate medium definition in each voxel, especially in areas of tissue transition. Since the behavior of human tissues is highly sensitive at low energies, this reduces the errors on calculated dose distribution. This method could be further developed to optimize the tissue characterization based on anatomic site.

  1. TU-C-17A-03: An Integrated Contour Evaluation Software Tool Using Supervised Pattern Recognition for Radiotherapy

    SciTech Connect (OSTI)

    Chen, H; Tan, J; Kavanaugh, J; Dolly, S; Gay, H; Thorstad, W; Anastasio, M; Altman, M; Mutic, S; Li, H

    2014-06-15

    Purpose: Radiotherapy (RT) contours delineated either manually or semiautomatically require verification before clinical usage. Manual evaluation is very time consuming. A new integrated software tool using supervised pattern contour recognition was thus developed to facilitate this process. Methods: The contouring tool was developed using an object-oriented programming language C# and application programming interfaces, e.g. visualization toolkit (VTK). The C# language served as the tool design basis. The Accord.Net scientific computing libraries were utilized for the required statistical data processing and pattern recognition, while the VTK was used to build and render 3-D mesh models from critical RT structures in real-time and 360° visualization. Principal component analysis (PCA) was used for system self-updating geometry variations of normal structures based on physician-approved RT contours as a training dataset. The inhouse design of supervised PCA-based contour recognition method was used for automatically evaluating contour normality/abnormality. The function for reporting the contour evaluation results was implemented by using C# and Windows Form Designer. Results: The software input was RT simulation images and RT structures from commercial clinical treatment planning systems. Several abilities were demonstrated: automatic assessment of RT contours, file loading/saving of various modality medical images and RT contours, and generation/visualization of 3-D images and anatomical models. Moreover, it supported the 360° rendering of the RT structures in a multi-slice view, which allows physicians to visually check and edit abnormally contoured structures. Conclusion: This new software integrates the supervised learning framework with image processing and graphical visualization modules for RT contour verification. This tool has great potential for facilitating treatment planning with the assistance of an automatic contour evaluation module in avoiding unnecessary manual verification for physicians/dosimetrists. In addition, its nature as a compact and stand-alone tool allows for future extensibility to include additional functions for physicians’ clinical needs.

  2. TU-F-BRE-04: Development of a High-Resolution EPID Based Dosimetry Strategy for Radiosurgery QA

    SciTech Connect (OSTI)

    Han, B; Ding, A; Xing, L; Wang, L

    2014-06-15

    Purpose: To systematically investigate a high spatial-resolution (0.2mm) electronic portal imaging device (EPID) for CyberKnife (CK) based radiosurgery system quality assurance (QA). Methods: An EPID-based dosimetric measurement technique is applied to CK output measurement and field size verification. A Monte Carlo (MC) simulated pixel-to-pixel EPID response specific to CK is used to convert a raw EPID-measured image of a radiosurgery field into water-based dose distribution. The output factors are measured using EPID for radiosurgery fields formed by fixed and variable aperture (Iris) cones. Circular fields of 5, 7.5, 10, 15, 30 and 60mm diameters are measured and compared with diode measurements. The equivalent diameters are determined by analyzing the area received dose greater than half maximum. Results: For both fixed and Iris cones, the EPID measured output factors of circular fields of 5mm to 60mm diameters are in good agreement with the radiosurgery diode measurements. The mean output differences are 1.0% and 1.5% for fixed and Iris cone respectively. The max differences are 2.2% for the 15mm fixed cone, and 1.8% for the 10mm Iris field. The equivalent diameters derived from the EPID measurements are in good agreement comparing to the water scan result with mean differences of 0.210.09mm and 0.020.22mm for fixed and Iris cone, respectively. The high detector density EPID is able to measure the whole radiation field and identify the field edge and center. Therefore, there is no need to align the detector center perfectly at field center and the setup time is greatly reduced for QA. Conclusion: The high spatial-resolution EPID is proved to be an accurate and efficient dosimetric tool for radiosurgery QA and especially useful in Cyberknife QA for variable aperture collimators.

  3. TU-C-18A-01: Models of Risk From Low-Dose Radiation Exposures: What Does the Evidence Say?

    SciTech Connect (OSTI)

    Bushberg, J; Boreham, D; Ulsh, B

    2014-06-15

    At dose levels of (approximately) 500 mSv or more, increased cancer incidence and mortality have been clearly demonstrated. However, at the low doses of radiation used in medical imaging, the relationship between dose and cancer risk is not well established. As such, assumptions about the shape of the dose-response curve are made. These assumptions, or risk models, are used to estimate potential long term effects. Common models include 1) the linear non-threshold (LNT) model, 2) threshold models with either a linear or curvilinear dose response above the threshold, and 3) a hormetic model, where the risk is initially decreased below background levels before increasing. The choice of model used when making radiation risk or protection calculations and decisions can have significant implications on public policy and health care decisions. However, the ongoing debate about which risk model best describes the dose-response relationship at low doses of radiation makes informed decision making difficult. This symposium will review the two fundamental approaches to determining the risk associated with low doses of ionizing radiation, namely radiation epidemiology and radiation biology. The strengths and limitations of each approach will be reviewed, the results of recent studies presented, and the appropriateness of different risk models for various real world scenarios discussed. Examples of well-designed and poorly-designed studies will be provided to assist medical physicists in 1) critically evaluating publications in the field and 2) communicating accurate information to medical professionals, patients, and members of the general public. Equipped with the best information that radiation epidemiology and radiation biology can currently provide, and an understanding of the limitations of such information, individuals and organizations will be able to make more informed decisions regarding questions such as 1) how much shielding to install at medical facilities, 2) at what dose level are risk vs. benefit discussions with patients appropriate, 3) at what dose level should we tell a pregnant woman that the baby’s health risk from a prenatal radiation exposure is “significant”, 4) is informed consent needed for patients undergoing medical imaging, and 5) at what dose level is evacuation appropriate after a radiological accident. Examples of the tremendous impact that choosing different risks models can have on the answers to these types of questions will be given.A moderated panel discussion will allow audience members to pose questions to the faculty members, each of whom is an established expert in his respective discipline. Learning Objectives: Understand the fundamental principles, strengths and limitations of radiation epidemiology and radiation biology for determining the risk from exposures to low doses of ionizing radiation Become familiar with common models of risk used to describe the dose-response relationship at low dose levels Learn to identify strengths and weaknesses in studies designed to measure the effect of low doses of ionizing radiation Understand the implications of different risk models on public policy and health care decisions.

  4. TU-A-12A-01: Consistency of Lung Expansion and Contraction During Respiration: Implications for Quantitative Imaging

    SciTech Connect (OSTI)

    Patton, T; Du, K; Bayouth, J; Christensen, G; Reinhardt, J

    2014-06-15

    Purpose: Four-dimensional computed tomography (4DCT) can be used to evaluate longitudinal changes in pulmonary function. The sensitivity of such measurements to identify function change may be improved with reproducible breathing patterns. The purpose of this study was to determine if inhale was more consistent than exhale, i.e., lung expansion during inhalation compared to lung contraction during exhalation. Methods: Repeat 4DCT image data acquired within a short time interval from 8 patients. Using a tissue volume preserving deformable image registration algorithm, Jacobian ventilation maps in two scanning sessions were computed and compared on the same coordinate for reproducibility analysis. Equivalent lung volumes (ELV) were used for 5 subjects and equivalent title volumes (ETV) for the 3 subjects who experienced a baseline shift between scans. In addition, gamma pass rate was calculated from a modified gamma index evaluation between two ventilation maps, using acceptance criterions of 2mm distance-to-agreement and 5% ventilation difference. The gamma pass rates were then compared using paired t-test to determine if there was a significant difference. Results: Inhalation was more reproducible than exhalation. In the 5 ELV subjects 78.5% of the lung voxels met the gamma criteria for expansion during inhalation when comparing the two scans, while significantly fewer (70.9% of the lung voxels) met the gamma criteria for contraction during exhalation (p = .027). In the 8 total subjects analyzed the average gamma pass rate for expansion during inhalation was 75.2% while for contraction during exhalation it was 70.3%; which trended towards significant (p = .064). Conclusion: This work implies inhalation is more reproducible than exhalation, when equivalent respiratory volumes are considered. The reason for this difference is unknown. Longitudinal investigation of pulmonary function change based on inhalation images appears appropriate for Jacobian-based measure of lung tissue expansion. NIH Grant: R01 CA166703.

  5. TU-C-BRE-02: A Novel, Highly Efficient and Automated Quality Assurance Tool for Modern Linear Accelerators

    SciTech Connect (OSTI)

    Goddu, S; Sun, B; Yaddanapudi, S; Kamal, G; Mutic, S; Baltes, C; Rose, S; Stinson, K

    2014-06-15

    Purpose: Quality assurance (QA) of complex linear accelerators is critical and highly time consuming. Varians Machine Performance Check (MPC) uses IsoCal phantom to test geometric and dosimetric aspects of the TrueBeam systems in <5min. In this study we independently tested the accuracy and robustness of the MPC tools. Methods: MPC is automated for simultaneous image-acquisition, using kV-and-MV onboard-imagers (EPIDs), while delivering kV-and-MV beams in a set routine of varying gantry, collimator and couch angles. MPC software-tools analyze the images to test: i) beam-output and uniformity, ii) positional accuracy of isocenter, EPIDs, collimating jaws (CJs), MLC leaves and couch and iii) rotational accuracy of gantry, collimator and couch. 6MV-beam dose-output and uniformity were tested using ionization-chamber (IC) and ICarray. Winston-Lutz-Tests (WLT) were performed to measure isocenter-offsets caused by gantry, collimator and couch rotations. Positional accuracy of EPIDs was evaluated using radio-opaque markers of the IsoCal phantom. Furthermore, to test the robustness of the MPC tools we purposefully miscalibrated a non-clinical TrueBeam by introducing errors in beam-output, energy, symmetry, gantry angle, couch translations, CJs and MLC leaves positions. Results: 6MV-output and uniformity were within 0.6% for most measurements with a maximum deviation of 1.0%. Average isocenter-offset caused by gantry and collimator rotations was 0.3160.011mm agreeing with IsoLock (0.274mm) and WLT (0.41mm). Average rotation-induced couch-shift from MPC was 0.3780.032mm agreeing with WLT (0.35mm). MV-and-kV imager-offsets measured by MPC were within 0.15mm. MPC predicted all machine miscalibrations within acceptable clinical tolerance. MPC detected the output miscalibrations within 0.61% while the MLC and couch positions were within 0.06mm and 0.14mm, respectively. Gantry angle miscalibrations were detected within 0.1. Conclusions: MPC is a useful tool for QA of TrueBeam systems and its automation makes it highly efficient for testing both geometric and dosimetric aspects of the machine. This is very important for hypo-fractionated SBRT treatments. Received support from Varian Medical Systems, Palo Alto, CA 94304-1038.

  6. TU-A-9A-07: X-Ray Acoustic Computed Tomography (XACT): 100% Sensitivity to X-Ray Absorption

    SciTech Connect (OSTI)

    Xiang, L; Ahmad, M; Nikoozadeh, A; Pratx, G; Khuri-Yakub, B; Xing, L

    2014-06-15

    Purpose: To assess whether X-ray acoustic computed tomography (XACT) is more sensitive to X-ray absorption than that of the conventional X-ray imaging. Methods: First, a theoretical model was built to analyze the X-ray absorption sensitivity of XACT imaging and conventional X-ray imaging. Second, an XACT imaging system was developed to evaluate the X-ray induced acoustic signal generation as well as the sensitivity improvement over transmission x-ray imaging. Ultra-short x-ray pulses (60-nanosecond) were generated from an X-ray source operated at the energy of 150 kVp with a 10-Hz repetition rate. The X-ray pulse was synchronized with the acoustic detection via a x-ray scintillation triggering to acquire the X-ray induced acoustic signal. Results: Theoretical analysis shows that X-ray induced acoustic signal is sensitive only to the X-ray absorption, while completely insensitive to out the X-ray scattering and fluorescence. XACT has reduced background and increased contrast-to-noise ratio, and therefore has increased sensitivity compared to transmission x-ray imaging. For a 50-μm size, gadolinium insertion in tissue exposed to 40 keV X-rays; the sensitivity of XACT imaging is about 28.9 times higher than that of conventional X-ray imaging. Conclusion: X-ray acoustic computer tomography (XACT) as a new imaging modality combines X-ray absorption contrast and high ultrasonic resolution in a single modality. It is feasible to improve the imaging sensitivity with XACT imaging compared with conventional X-ray imaging. Taking advantage of the high ultrasonic resolution, it is possible to perform 3-D imaging with a single x-ray pulse with arrays of transducers without any mechanical motion of the imaging system. This single-shot capability offers the potential of reducing radiation dose by a factor of 1000, and imaging 100 times faster when compared to the conventional X-ray CT, and thus revolutionizing x-ray imaging applications in medicine and biology. The authors gratefully acknowledge the Department of Defense Prostate Cancer Research Programs W81XWH-13-1-0481 (LX), the National Institutes of Health 1R01 CA133474 and 1R21 A153587, and SRFDP (20124407120012) for funding.

  7. TU-A-18A-01: Basic Principles of PET/CT, Calibration Methods and Contrast Recovery Across Multiple Cameras

    SciTech Connect (OSTI)

    Kappadath, S; Nye, J

    2014-06-15

    This continuing education session will discuss the physical principles of PET/CT imaging and characterization of contrast recovery using accreditation phantoms. A detailed overview will be given on the physical principles of PET including positron decay physics, 2D and 3D data acquisition, time-of-flight, scatter correction, CT attenuation correction, and image reconstruction. Instrument quality control and calibration procedures will be discussed. Technical challenges, common image artifacts and strategies to mitigate these issues will also be discussed. Data will be presented on acquisition techniques and reconstruction parameters affecting contrast recovery. The discussion will emphasize the minimization of reconstruction differences in quantification metrics such as SUV and contrast recovery coefficients for the NEMA and ACR clinical trial phantoms. Data from new and older generation scanners will be shown including comparison of contrast recovery measurements to their analytical solutions. The goal of this session is to update attendees on the quality control and calibration of PET/CT scanners, on methods to establish a common calibration for PET/CT scanners to control for instrument variance across multiple sites. Learning Objectives: Review the physical principles of PET/CT, quality control and calibration Gain further understanding on how to apply techniques for improving quantitative agreement across multiple cameras Describe the differences between measured and expected contrast recovery for the NEMA and ACR PET phantoms.

  8. TU-A-9A-10: Verification of Photoacoustic Computed Tomography Perfusion Imaging Using DCE-CT

    SciTech Connect (OSTI)

    Roth, A; Krutulis, M; Verleker, A; Stantz, K

    2014-06-15

    Purpose: We propose to verify quantifiable perfusion information generated by a Photoacoustic Computed Tomography (PCT) scanner using Dynamic Contrast-Enhanced CT (DCE-CT), and to investigate physicsbased models of acoustic properties of tissue and photon transport to improve quantification. These corrections first necessitate a skin identifying algorithms to reduce speed-of-sound blurring and empirical photon correction methods. Methods: Xenograft mice (n=5) of breast cancer was imaged using DCE-CT which was followed by DCE-PCT. To obtain CT perfusion data, each mouse was i.v. injected (0.2mL Isovue @0.5mL/min) and subsequent radio-opaque time curves fit to a 2-compartmental model on a voxel-wise basis. For DCE-PCT, different concentrations of ICG (250, 125, and 62.5 micro-Molar) were injected at the same rate, but also acquired at different sampling rates (3, 6, and 12 seconds). The time intensity curves from PCT were fit to a 1-compartmental model on a voxel by voxel basis. The images were coregistered (Oncentra) based on the structural similarities of the tumor vasculature after which we compared both the contrastenhanced dynamics and the vascular physiology. Results: Moderate to high doses of ICG impact the washin phase of the PCT contrast due to photon losses as a function of depth. A semi-automatic algorithm has been developed to identify the skin margin, and subsequent MC and empirical models of photon transport and variations in speed-of-sound are being evaluated. Conclusion: From our results we find that there is a need to apply photon and speed-of-sound corrections to our PCT data to improve the quantifiable image data at depth in the tumor for PCT. The dose and injection rate may help in reducing large systematic effects. Our project is partially funded by a NIH SBIR grant.

  9. Summary - System Level Modeling and Simulation Tools for Hanford

    Office of Environmental Management (EM)

    The ob curren plannin Dispos yield re to mod plannin to imp (4) det actual * Th th Th co no in pl * In fo op sy as di re de co an * Th en m ha ev sc The pu techni projec Site: H roject: H Report Date: S ited States valuation in Su Why DOE bjective of the r nt Process Simu ng basis for OR sition System P easonable esti del facilities cur ng or operation rove the rate o termine if addit execution of in What th he current Syst hat are limited t hese tools curr omposition, res ot meeting was itial

  10. UTILITY_ID","UTILNAME","STATE_CODE","YEAR","MONTH","RES_REV (Thousand $)","RES_S

    U.S. Energy Information Administration (EIA) Indexed Site

    9","AK",2009,1,6541.05,26261.245,30585,8314.598,32767.826,10631,1391.23,7394.973,534,0,0,0,16246.878,66424.044,41750 213,"Alaska Electric Light&Power Co","AK",2009,1,3587,16219,13713,2198,10943,2143,1053,5362,91,0,0,0,6838,32524,15947 219,"Alaska Power Co","AK",2009,1,676.033,2544.992,4478,879.743,3565.976,2065,0,0,0,0,0,0,1555.776,6110.968,6543 599,"Anchorage Municipal Light and

  11. UTILITY_ID","UTILNAME","STATE_CODE","YEAR","MONTH","RES_REV (Thousand $)","RES_S

    U.S. Energy Information Administration (EIA) Indexed Site

    0","AK",2010,1,5889.296,25346.726,30607,7768.547,32303.665,10842,1432.777,7587.714,510,0,0,0,15090.62,65238.105,41959 213,"Alaska Electric Light&Power Co","AK",2010,1,1535.941,15011.6,13783,980.665,11721.382,2156,987.54,11255.996,91,0,0,0,3504.146,37988.978,16030 219,"Alaska Power and Telephone Co","AK",2010,1,668.02,2319.376,4592,921.903,3261.675,2099,0,0,0,0,0,0,1589.923,5581.051,6691 599,"Anchorage Municipal Light and

  12. UTILITY_ID","UTILNAME","STATE_CODE","YEAR","MONTH","RES_REV (Thousand $)","RES_S

    U.S. Energy Information Administration (EIA) Indexed Site

    1","AK",2011,1,6234.999,25389.363,30394,8864.339,33363.108,11226,1796.286,8445.807,406,0,0,0,16895.624,67198.278,42026 213,"Alaska Electric Light&Power Co","AK",2011,1,1913.906,15780.043,13800,1191.056,11892.612,2172,749.249,8392.574,93,0,0,0,3854.211,36065.229,16065 219,"Alaska Power and Telephone Co","AK",2011,1,776.905,2477.956,4683,989.646,3281.279,2102,0,0,0,0,0,0,1766.551,5759.235,6785 599,"Anchorage Municipal Light and

  13. Distributed H{sub 2} Supply for Fuel Cell Utility Vehicles Year 6 - Activity 3.5 - Development fo a National Center for Hydrogen Technology

    SciTech Connect (OSTI)

    Almlie, Jay

    2012-04-15

    The Energy & Environmental Research Center (EERC) has developed a high-pressure hydrogen production system that reforms a liquid organic feedstock and water at operating pressures up to 800 bar (~12,000 psig). The advantages of this system include the elimination of energy-intensive hydrogen compression, a smaller process footprint, and the elimination of gaseous or liquid hydrogen transport. This system could also potentially enable distributed hydrogen production from centralized coal. Processes have been investigated to gasify coal and then convert the syngas into alcohol or alkanes. These alcohols and alkanes could then be easily transported in bulk to distributed high-pressure water-reforming (HPWR)-based systems to deliver hydrogen economically. The intent of this activity was to utilize the EERC’s existing HPWR hydrogen production process, previously designed and constructed in a prior project phase, as a basis to improve operational and production performance of an existing demonstration unit. Parameters to be pursued included higher hydrogen delivery pressure, higher hydrogen production rates, and the ability to refill within a 5-minute time frame.

  14. Frit Development Efforts for Sludge Batch 4 (SB4): Operating Window Assessments fo Scenarios Leading Up to the Selected Preparation Plan for SB4

    SciTech Connect (OSTI)

    Peeler, D

    2006-03-21

    The objective of this report is to document technical information that has been provided to Defense Waste Processing Facility (DWPF) and Closure Business Unit (CBU) personnel as part of the frit development support for Sludge Batch 4 (SB4). The information presented in this report includes projected operating windows (expressed in terms of waste loading) for various sludge blending and/or washing options coupled with candidate frits of interest. Although the Nominal Stage assessment serves as the primary tool for these evaluations, select systems were also evaluated using a Variation Stage assessment in which compositional variations were introduced. In addition, assessments of the impacts of nepheline formation potential and the SO{sub 4}{sup -} solubility limit on the projected operating windows are also provided. Although this information was used as part of the technical basis leading to CBU's development of the preferred SB4 preparation plan, none of the options presented in this report was selected as the preferred plan. Therefore, the information is presented without significant interpretation of the resulting operating windows, but the projected windows are provided so additional insight can be explored if desired. Detailed assessments of the projected operating windows (using both Nominal and Variation Stage assessments) of the preferred sludge preparation plan with candidate frits are to be documented elsewhere. The information provided in this report is focused solely on model-based projections of the operating windows for various SB4 blending strategies of interest. Although nepheline formation potential is monitored via model predictions as a part of this assessment, experimental work investigating the impact of nepheline on glass quality is also being addressed in a parallel study. The results of this paper study and the experimental assessments of melt rate, SO{sub 4} solubility, and/or nepheline formation potential are all critical components of the inputs into the frit selection process for SB4.

  15. Design & development fo a 20-MW flywheel-based frequency regulation power plant : a study for the DOE Energy Storage Systems program.

    SciTech Connect (OSTI)

    Rounds, Robert; Peek, Georgianne Huff

    2009-01-01

    This report describes the successful efforts of Beacon Power to design and develop a 20-MW frequency regulation power plant based solely on flywheels. Beacon's Smart Matrix (Flywheel) Systems regulation power plant, unlike coal or natural gas generators, will not burn fossil fuel or directly produce particulates or other air emissions and will have the ability to ramp up or down in a matter of seconds. The report describes how data from the scaled Beacon system, deployed in California and New York, proved that the flywheel-based systems provided faster responding regulation services in terms of cost-performance and environmental impact. Included in the report is a description of Beacon's design package for a generic, multi-MW flywheel-based regulation power plant that allows accurate bids from a design/build contractor and Beacon's recommendations for site requirements that would ensure the fastest possible construction. The paper concludes with a statement about Beacon's plans for a lower cost, modular-style substation based on the 20-MW design.

  16. Microsoft Word - Title Page Wood Feeding Beetle 2013.docx

    Office of Scientific and Technical Information (OSTI)

    ... which could be utilized fo r ethanolic biofuel production 1, Despite the abundance o f ... candidate fo r m ining novel lignocellulose degrading enzymes fo r biofuel applications. ...

  17. Microsoft PowerPoint - 8880 December 2011 OSDF Inspection Report Screen Res.ppt

    Office of Legacy Management (LM)

    880.1 12/11 On-Site Disposal Facility Inspection Report December 2011 6319D-5992c 8880.2 12/11 East Face Cell 1 West Face Cell 1 6319D-5995 6319D-6001 8880.3 12/11 North Face Cell 1 North Drainage (looking west) 6319D-5997 6319D-5998 8880.4 12/11 East Face Cell 2 West Face Cell 2 6319D-6002 6319D-5994 8880.5 12/11 East Face Cell 3 West Face Cell 3 6319D-6003 6319D-5993 8880.6 12/11 East Face Cell 4 West Face Cell 4 6319D-6004 6319D-5991 8880.7 12/11 East Face Cell 5 West Face Cell 5 6319D-6006

  18. Microsoft PowerPoint - 8939 June 2013 OSDF Inspection Report - ScreenRes.ppt [Compatibility Mode]

    Office of Legacy Management (LM)

    9.1 06/13 On-Site Disposal Facility Inspection Report June 2013 8322-2 06/06/13 8939.2 06/13 East Face Cell 1 West Face Cell 1 6319D-6174 6319D-6197 8939.3 06/13 North Face Cell 1 North Drainage (looking west) 6319D-6172 6319D-6171 8939.4 06/13 East Face Cell 2 West Face Cell 2 6319D-6195 6319D-6175 8939.5 06/13 East Face Cell 3 West Face Cell 3 6319D-6194 6319D-6176 8939.6 06/13 East Face Cell 4 West Face Cell 4 6319D-6193 6319D-6177 8939.7 06/13 East Face Cell 5 West Face Cell 5 6319D-6192

  19. Business Opportunity Forum List July 2016 RES Tulsa Alpha Webpage Final.xlsx.pdf

    Office of Environmental Management (EM)

    Greenhouse Gases | Department of Energy Establishes Program to Reduce Foreign Oil Dependency, Greenhouse Gases Bush Administration Establishes Program to Reduce Foreign Oil Dependency, Greenhouse Gases April 10, 2007 - 12:34pm Addthis WASHINGTON, DC - In step with the Bush Administration's call to increase the supply of alternative and renewable fuels nationwide, the U.S. Environmental Protection Agency today established the nation's first comprehensive Renewable Fuel Standard (RFS) program.

  20. Indian Energy & Energy Infrastructure to be Showcased at RES 2012 in Las Vegas

    Broader source: Energy.gov [DOE]

    Our mission as a Department – to ensure America’s security and prosperity by addressing its energy, environmental, and nuclear challenges through transformative science and technology solutions –...

  1. Microsoft Word - NG_ResQrySys_UsersGuide_Sept2015-FINAL.docx

    Gasoline and Diesel Fuel Update (EIA)

    ... the Query System is a web-based system, no download or installation is necessary. All that is needed to run the Query System is a PC with up-to-date web-browsing software (such ...

  2. Microsoft PowerPoint - C-Mod_quarterly_res_highlights_21.ppt

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    confinement "I-mode" - Neon and nitrogen seeded plasmas (all regimes) - H-mode pedestal physics (APS invited) - ITER discharge development - B-coated Mo tile operation -...

  3. Penn State HyRES Laboratory Wind Turbine | Open Energy Information

    Open Energy Info (EERE)

    - Yankton School District Wind Project

  4. TU-C-12A-07: Characterization of Longitudinal Reproducibility of Quantitative Diffusion Imaging Data Acquired with Four Different Protocols Using a Phantom

    SciTech Connect (OSTI)

    Li, X; Buzzelli, M; Randazzo, W; Yanasak, N

    2014-06-15

    Purpose: To characterize and compare the longitudinal reproducibility of diffusion imaging data acquired with four different protocols using a phantom. Methods: The Diffusive Quantitative Imaging Phantom (DQIP) was constructed using fifteen cylindrical compartments within a larger compartment, filled with deionized water doped with CuSO4 and NaCl. The smaller compartments contained arrays of hexagonal or cylindrical glass capillaries of varying inner diameters, for differing restraint of water diffusion. The sensitivity of diffusion imaging metrics to signal-to-noise ratio (SNR) was probed by doping compartments with differing ratios of deuterium oxide to H2O. A cork phantom enclosure was constructed to increase thermal stability during scanning and a cork holder was made to reproduce scanner positioning. Four different protocols of DWI (diffusion weighted imaging) and DTI (Diffusion tensor imaging) imaging were assembled on a GE Excite HDx 3.0T MRI scanner to collect imaging data over 9-10 days. Data was processed with in-house software created in Matlab to obtain fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values. Results: All DTI and DWI sequences showed good longitudinal stability of mean FA and ADC values per compartment, exhibiting low standard deviation ∼9%. A t-test was performed to compare mean FA values from the DTI clinical protocol to those of the DTI special protocol, indicating significantly different values in the majority of compartments. ANOVA performed on ADC values for all DTI and DWI sequences also showed significantly different values in a majority of compartments. Conclusion: This work has the potential for quantifying systemic variations between diffusion imaging sequences from different platforms. Characterization of DWI and DTI performance were done over four sequences with predictable results. This data suggests that the DQIP phantom may be a reliable method of monitoring day-to-day and scan-to-scan variation in diffusion imaging sequences from different platforms. Schott Glass North America and The Phantom Laboratory have donated materials and personnel time to this project.

  5. TU-F-18A-04: Use of An Image-Based Material-Decomposition Algorithm for Multi-Energy CT to Determine Basis Material Densities

    SciTech Connect (OSTI)

    Li, Z; Leng, S; Yu, L; McCollough, C

    2014-06-15

    Purpose: Published methods for image-based material decomposition with multi-energy CT images have required the assumption of volume conservation or accurate knowledge of the x-ray spectra and detector response. The purpose of this work was to develop an image-based material-decomposition algorithm that can overcome these limitations. Methods: An image-based material decomposition algorithm was developed that requires only mass conservation (rather than volume conservation). With this method, using multi-energy CT measurements made with n=4 energy bins, the mass density of each basis material and of the mixture can be determined without knowledge of the tube spectra and detector response. A digital phantom containing 12 samples of mixtures from water, calcium, iron, and iodine was used in the simulation (Siemens DRASIM). The calibration was performed by using pure materials at each energy bin. The accuracy of the technique was evaluated in noise-free and noisy data under the assumption of an ideal photon-counting detector. Results: Basis material densities can be estimated accurately by either theoretic calculation or calibration with known pure materials. The calibration approach requires no prior information about the spectra and detector response. Regression analysis of theoretical values versus estimated values results in excellent agreement for both noise-free and noisy data. For the calibration approach, the R-square values are 0.9960+/−0.0025 and 0.9476+/−0.0363 for noise-free and noisy data, respectively. Conclusion: From multi-energy CT images with n=4 energy bins, the developed image-based material decomposition method accurately estimated 4 basis material density (3 without k-edge and 1 with in the range of the simulated energy bins) even without any prior information about spectra and detector response. This method is applicable to mixtures of solutions and dissolvable materials, where volume conservation assumptions do not apply. CHM receives research support from NIH and Siemens Healthcare.

  6. TU-A-17A-02: In Memoriam of Ben Galkin: Virtual Tools for Validation of X-Ray Breast Imaging Systems

    SciTech Connect (OSTI)

    Myers, K; Bakic, P; Abbey, C; Kupinski, M; Mertelmeier, T

    2014-06-15

    This symposium will explore simulation methods for the preclinical evaluation of novel 3D and 4D x-ray breast imaging systems – the subject of AAPM taskgroup TG234. Given the complex design of modern imaging systems, simulations offer significant advantages over long and costly clinical studies in terms of reproducibility, reduced radiation exposures, a known reference standard, and the capability for studying patient and disease subpopulations through appropriate choice of simulation parameters. Our focus will be on testing the realism of software anthropomorphic phantoms and virtual clinical trials tools developed for the optimization and validation of breast imaging systems. The symposium will review the stateof- the-science, as well as the advantages and limitations of various approaches to testing realism of phantoms and simulated breast images. Approaches based upon the visual assessment of synthetic breast images by expert observers will be contrasted with approaches based upon comparing statistical properties between synthetic and clinical images. The role of observer models in the assessment of realism will be considered. Finally, an industry perspective will be presented, summarizing the role and importance of virtual tools and simulation methods in product development. The challenges and conditions that must be satisfied in order for computational modeling and simulation to play a significantly increased role in the design and evaluation of novel breast imaging systems will be addressed. Learning Objectives: Review the state-of-the science in testing realism of software anthropomorphic phantoms and virtual clinical trials tools; Compare approaches based upon the visual assessment by expert observers vs. the analysis of statistical properties of synthetic images; Discuss the role of observer models in the assessment of realism; Summarize the industry perspective to virtual methods for breast imaging.

  7. TU-F-18C-02: Increasing Amorphous Selenium Thickness in Direct Conversion Flat-Panel Imagers for Contrast-Enhanced Dual-Energy Breast Imaging

    SciTech Connect (OSTI)

    Scaduto, DA; Hu, Y-H; Zhao, W

    2014-06-15

    Purpose: Contrast-enhanced (CE) breast imaging using iodinated contrast agents requires imaging with x-ray spectra at energies greater than those used in mammography. Optimizing amorphous selenium (a-Se) flat panel imagers (FPI) for this higher energy range may increase lesion conspicuity. Methods: We compare imaging performance of a conventional FPI with 200 μm a-Se conversion layer to a prototype FPI with 300 μm a-Se layer. Both detectors are evaluated in a Siemens MAMMOMAT Inspiration prototype digital breast tomosynthesis (DBT) system using low-energy (W/Rh 28 kVp) and high-energy (W/Cu 49 kVp) x-ray spectra. Detectability of iodinated lesions in dual-energy images is evaluated using an iodine contrast phantom. Effects of beam obliquity are investigated in projection and reconstructed images using different reconstruction methods. The ideal observer signal-to-noise ratio is used as a figure-of-merit to predict the optimal a-Se thickness for CE lesion detectability without compromising conventional full-field digital mammography (FFDM) and DBT performance. Results: Increasing a-Se thickness from 200 μm to 300 μm preserves imaging performance at typical mammographic energies (e.g. W/Rh 28 kVp), and improves the detective quantum efficiency (DQE) for high energy (W/Cu 49 kVp) by 30%. While the more penetrating high-energy x-ray photons increase geometric blur due to beam obliquity in the FPI with thicker a-Se layer, the effect on lesion detectability in FBP reconstructions is negligible due to the reconstruction filters employed. Ideal observer SNR for CE objects shows improvements in in-plane detectability with increasing a-Se thicknesses, though small lesion detectability begins to degrade in oblique projections for a-Se thickness above 500 μm. Conclusion: Increasing a-Se thickness in direct conversion FPI from 200 μm to 300 μm improves lesion detectability in CE breast imaging with virtually no cost to conventional FFDM and DBT. This work was partially supported by a research grant from Siemens Healthcare.

  8. TU-F-BRE-01: A High Resolution Micro Fiber Scintillator Detector Optimized for SRS and SBRT in Vivo Real Time Treatment Verification

    SciTech Connect (OSTI)

    Izaguirre, E; Rangaraj, D; Price, S; Knewtson, T; Loyalka, S

    2014-06-15

    Purpose: We have built a high resolution real time scintillating fiber detector prototype to determine in real time the accuracy of stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT) treatments when only a fraction of the planned dose was delivered. The motivation of this work is to enhance dose delivery accuracy and to achieve error free radiosurgery. Methods: A high density array of scintillating fibers and a high speed photo detectors array were integrated to implement a high resolution real time dosimeter that can sample with high resolution pulsed SRS and SBRT beams cross sections. The high efficiency of the developed system allows to read each linac pulse in real time and to compute the accumulated dose and dose errors when only a fraction of the beam was delivered. The fibers are highly packed in a substrate that is directly coupled to two 128 pixel arrays with a pitch matching the fiber spacing to achieve accurate spatial localization. The small cross section of the fiber array allows stacking multiple fiber arrays to measure independent angular profiles that are digitally processed in parallel for real time dosimetry. Results: We implemented a high density array detector prototype with a pitch of 0.5 mm, readout speed of 1.2 msec, and a response time of 0.5 usec. The fast reading speed has the capability to determining the dose in flattening free filter beams. The detector can be installed in transmission mode at the output port of a micro-MLC. Treatment deviations smaller than 3% are detected when less than 1/100 of the planned dose was delivered. Conclusions: We built a prototype of a high resolution fiber scintillator array detector for SRS and SBRT in vivo dosimetry. Results show that the developed detector has the potential to assure error free SRS and SBRT treatments.

  9. TU-F-17A-09: Four-Dimensional Cone Beam CT Ventilation Imaging Can Detect Interfraction Lung Function Variations for Locally Advanced Lung Cancer Patients

    SciTech Connect (OSTI)

    Kipritidis, J; Keall, P; Hugo, G; Weiss, E; Williamson, J

    2014-06-15

    Purpose: Four-dimensional cone beam CT ventilation imaging (4D-CBCT VI) is a novel functional lung imaging modality requiring validation. We hypothesize that 4D-CBCT VI satisfies a necessary condition for validity: that intrafraction variations (e.g. due to poor 4D-CBCT image quality) are substantially different to interfraction variations (e.g. due to changes in underlying function). We perform the first comparison of intrafraction (pre/post fraction) and interfraction (week-to-week) 4D-CBCT VIs for locally advanced non small cell lung cancer (LA NSCLC) patients undergoing radiation therapy. Methods: A total of 215 4D-CBCT scans were acquired for 19 LA NSCLC patients over 4-6 weeks of radiation therapy, including 75 pairs of pre-/post-fraction scans on the same day. 4D-CBCT VIs were obtained by applying state-of-the-art, B-spline deformable image registration to obtain the Jacobian determinant of deformation between the end-exhale and end-inhale phases. All VIs were deformably registered to the corresponding first day scan, normalized between the 10th and 90th percentile values and cropped to the ipsilateral lung only. Intrafraction variations were assessed by computing the mean and standard deviation of voxel-wise differences between all same-day pairs of pre-/post-fraction VIs. Interfraction differences were computed between first-day VIs and treatment weeks 2, 4 and 6 for all 19 patients. We tested the hypothesis by comparing cumulative distribution functions (CDFs) of intrafraction and interfraction ventilation differences using two-sided Kolmogorov-Smirnov goodness-of-fit tests. Results: The (mean ± std. dev.) of intrafraction differences was (−0.007 ± 0.079). Interfraction differences for weeks 2, 4 and 6 were (−0.035 ± 0.103), (−0.006 ± 0.094) and (−0.019 ± 0.127) respectively. For week 2, the changes in CDFs for intrafraction and interfraction differences approached statistical significance (p=0.099). Conclusion: We have shown that 4D-CBCT VI can satisfy a necessary condition for validity; intrafraction variations do not limit the ability to measure interfraction variations in LA NSCLC patients. This work is supported by a Cancer Institute NSW Early Career Fellowship, an NHMRC Australia Fellowship and NIH P01CA116602.

  10. TU-F-12A-06: BEST IN PHYSICS (IMAGING) - A Novel Catheter-Based Radionuclide Imaging System to Characterize Atherosclerotic Plaque

    SciTech Connect (OSTI)

    Zaman, R; Kosuge, H; Carpenter, C; Pratx, G; Sun, C; McConnell, M; Xing, L

    2014-06-15

    Purpose: Atherosclerosis underlies coronary artery diseases, the leading cause of death in the United States and worldwide. In this study, we developed a novel catheter-based radionuclide imaging (CRI) system to image 18F-fluorodeoxyglucose (18F-FDG), a radionuclide, a marker of vascular inflammation, in murine carotid arteries and characterized the system for spatial resolution from multiple scintillating materials. Methods: The catheter system includes 35 mm and 8 mm fixed focal length lenses, which are subsequently connected to a CMOS camera and fiber holder. The distal ferrule of an image bundle is terminated with a wide-angle lens. The novelty of this system is a scintillating balloon with a crystal tip in the front of the wide angle lens to image light from the decay of 18F-FDG emission signal. The scintillating balloon is fabricated from 1mL of silicone RTV catalyst mixed with 1 mL base and 50 mg/mL calcium fluoride doped with Europium (CaF2:Eu). To identify the optimal scintillating materials with respect to resolution, we calculated modulation transfer function (MTF) of Yttrium Aluminum Garnet doped with Cerium (YAG:Ce), anthracene, and CaF2:Eu phosphors using a thin line optical phantom (Fig. 1a-1b). Macrophage-rich FVB murine atherosclerotic carotid plaque model (n = 4) was used in ex vivo experiments. Confirmatory imaging was also performed by an external optical imaging system (IVIS-200). Results: Analysis of the different phosphors (Fig 1b) showed that CaF2:Eu enabled the best resolution of 1.2?m. The CRI system visualized 18F-FDG in atherosclerotic plaques (Fig. 1d). The ligated left carotid (LR) artery exhibited 4 higher 18F-FDG signal intensity compared to the non-ligated right carotid (negative control) artery (1.6510{sup 2} 4.0710{sup 1} vs. 4.4410{sup 1}2.1710{sup 0}, A.U., p = 0.005) and confirmed with IVIS-200 (Fig. 1d). Conclusion: This CRI system enables high-resolution and sensitive detection of 18F-FDG uptake by murine atherosclerotic plaques.

  11. TU-C-BRE-04: 3D Gel Dosimetry Using ViewRay On-Board MR Scanner: A Feasibility Study

    SciTech Connect (OSTI)

    Zhang, L; Du, D; Green, O; Rodriguez, V; Wooten, H; Xiao, Z; Yang, D; Hu, Y; Li, H

    2014-06-15

    Purpose: MR based 3D gel has been proposed for radiation therapy dosimetry. However, access to MR scanner has been one of the limiting factors for its wide acceptance. Recent commercialization of an on-board MR-IGRT device (ViewRay) may render the availability issue less of a concern. This work reports our attempts to simulate MR based dose measurement accuracy on ViewRay using three different gels. Methods: A spherical BANG gel dosimeter was purchased from MGS Research. Cylindrical MAGIC gel and Fricke gel were fabricated in-house according to published recipes. After irradiation, BANG and MAGIC were imaged using a dual-echo spin echo sequence for T2 measurement on a Philips 1.5T MR scanner, while Fricke gel was imaged using multiple spin echo sequences. Difference between MR measured and TPS calculated dose was defined as noise. The noise power spectrum was calculated and then simulated for the 0.35 T magnetic field associated with ViewRay. The estimated noise was then added to TG-119 test cases to simulate measured dose distributions. Simulated measurements were evaluated against TPS calculated doses using gamma analysis. Results: Given same gel, sequence and coil setup, with a FOV of 1809090 mm3, resolution of 333 mm3, and scanning time of 30 minutes, the simulated measured dose distribution using BANG would have a gamma passing rate greater than 90% (3%/3mm and absolute). With a FOV 1809090 mm3, resolution of 445 mm3, and scanning time of 45 minutes, the simulated measuremened dose distribution would have a gamma passing rate greater than 97%. MAGIC exhibited similar performance while Fricke gel was inferior due to much higher noise. Conclusions: The simulation results demonstrated that it may be feasible to use MAGIC and BANG gels for 3D dose verification using ViewRay low-field on-board MRI scanner.

  12. TU-C-BRE-11: 3D EPID-Based in Vivo Dosimetry: A Major Step Forward Towards Optimal Quality and Safety in Radiation Oncology Practice

    SciTech Connect (OSTI)

    Mijnheer, B; Mans, A; Olaciregui-Ruiz, I; Rozendaal, R; Spreeuw, H; Herk, M van

    2014-06-15

    Purpose: To develop a 3D in vivo dosimetry method that is able to substitute pre-treatment verification in an efficient way, and to terminate treatment delivery if the online measured 3D dose distribution deviates too much from the predicted dose distribution. Methods: A back-projection algorithm has been further developed and implemented to enable automatic 3D in vivo dose verification of IMRT/VMAT treatments using a-Si EPIDs. New software tools were clinically introduced to allow automated image acquisition, to periodically inspect the record-and-verify database, and to automatically run the EPID dosimetry software. The comparison of the EPID-reconstructed and planned dose distribution is done offline to raise automatically alerts and to schedule actions when deviations are detected. Furthermore, a software package for online dose reconstruction was also developed. The RMS of the difference between the cumulative planned and reconstructed 3D dose distributions was used for triggering a halt of a linac. Results: The implementation of fully automated 3D EPID-based in vivo dosimetry was able to replace pre-treatment verification for more than 90% of the patient treatments. The process has been fully automated and integrated in our clinical workflow where over 3,500 IMRT/VMAT treatments are verified each year. By optimizing the dose reconstruction algorithm and the I/O performance, the delivered 3D dose distribution is verified in less than 200 ms per portal image, which includes the comparison between the reconstructed and planned dose distribution. In this way it was possible to generate a trigger that can stop the irradiation at less than 20 cGy after introducing large delivery errors. Conclusion: The automatic offline solution facilitated the large scale clinical implementation of 3D EPID-based in vivo dose verification of IMRT/VMAT treatments; the online approach has been successfully tested for various severe delivery errors.

  13. TU-F-17A-06: Motion Stability and Dosimetric Impact of Spirometer-Based DIBH-RT of Left-Sided Breast Cancer

    SciTech Connect (OSTI)

    McKenzie, E; Yang, W; Burnison, M; Mirhadi, A; Hakimian, B; Stephen, S; Robert, R; Yue, Y; Sandler, H; Fraass, B

    2014-06-15

    Purpose: Patients undergoing radiotherapy (RT) for left-sided breast cancer have increased risk of coronary artery disease. Deep Inhalation Breath Hold assisted RT (DIBH-RT) is shown to increase the geometric separation of the target area and heart, reducing cardiac radiation dose. The purposes of this study are to use Cine MV portal images to determine the stability of spirometer-guided DIBH-RT and examine the dosimetric cardiopulmonary impact of this technique. Methods: Twenty consecutive patients with left-sided breast cancer were recruited to the IRB-approved study. Free-breathing (FB) and DIBH-CT's were acquired at simulation. Rigid registration of the FB-CT and DIBH-CT was performed using primarily breast tissue. Treatment plans were created for each FB-CT and DIBH-CT using identical paired tangent fields with field-in-field or electronic compensation techniques. Dosimetric evaluation included mean and maximum (Dmax) doses for the left anterior descending artery (LAD), mean heart dose, and left lung V20. Cine MV portal images were acquired for medial and lateral fields during treatment. Analysis of Cine images involved chest wall segmentation using an algorithm developed in-house. Intra- and inter-fractional chest wall motion were determined through affine registration to the first frame of each Cine. Results: Dose to each cardiac structure evaluated was significantly (p<0.001) reduced with the DIBH plans. Mean heart dose decreased from 2.9(0.96.6) to 1.6(0.65.3) Gy; mean LAD dose from 16.6(343.6) to 7.4(1.732.7) Gy; and LAD Dmax from 35.4 (6.153) to 18.4(2.551.2) Gy. No statistically significant reduction was found for the left lung V20. Average AP and SI median chest wall motion (intrafractional) was 0.1 (SD=0.9) and 0.5 (SD=1.1) mm, respectively. Average AP inter-fractional chest wall motion was 2.0 (SD=1.4) mm. Conclusion: Spirometer-based DIBH treatments of the left breast are reproducible both inter- and intra-fractionally, and provide a statistically and potentially clinically useful dosimetric advantage to cardiac structures.

  14. TU-C-12A-12: Differentiating Bone Lesions and Degenerative Joint Disease in NaF PET/CT Scans Using Machine Learning

    SciTech Connect (OSTI)

    Perk, T; Bradshaw, T; Muzahir, S; Jeraj, R; Meyer, E

    2014-06-15

    Purpose: [F-18]NaF PET can be used to image bone metastases; however, tracer uptake in degenerative joint disease (DJD) often appears similar to metastases. This study aims to develop and compare different machine learning algorithms to automatically identify regions of [F-18]NaF scans that correspond to DJD. Methods: 10 metastatic prostate cancer patients received whole body [F-18]NaF PET/CT scans prior to treatment. Image segmentation resulted in 852 ROIs, 69 of which were identified by a nuclear medicine physician as DJD. For all ROIs, various PET and CT textural features were computed. ROIs were divided into training and testing sets used to train eight different machine learning classifiers. Classifiers were evaluated based on receiver operating characteristics area under the curve (AUC), sensitivity, specificity, and positive predictive value (PPV). We also assessed the added value of including CT features in addition to PET features for training classifiers. Results: The training set consisted of 37 DJD ROIs with 475 non-DJD ROIs, and the testing set consisted of 32 DJD ROIs with 308 non-DJD ROIs. Of all classifiers, generalized linear models (GLM), decision forests (DF), and support vector machines (SVM) had the best performance. AUCs of GLM (0.929), DF (0.921), and SVM (0.889) were significantly higher than the other models (p<0.001). GLM and DF, overall, had the best sensitivity, specificity, and PPV, and gave a significantly better performance (p<0.01) than all other models. PET/CT GLM classifiers had higher AUC than just PET or just CT. GLMs built using PET/CT information had superior or comparable sensitivities, specificities and PPVs to just PET or just CT. Conclusion: Machine learning algorithms trained with PET/CT features were able to identify some cases of DJD. GLM outperformed the other classification algorithms. Using PET and CT information together was shown to be superior to using PET or CT features alone. Research supported by the Prostate Cancer Foundation.

  15. TU-C-17A-05: Dose Domain Optimization of MLC Leaf Patterns for Highly Complicated 4Ï€ IMRT Plans

    SciTech Connect (OSTI)

    Nguyen, D; Yu, V; Ruan, D; Semwal, H; Cao, M; Low, D; Sheng, K; O’Connor, D

    2014-06-15

    Purpose: Highly conformal non-coplanar 4π radiotherapy plans typically require more than 20 intensity-modulated fields to deliver. A novel method to calculate multileaf collimator (MLC) leaf patterns is introduced to maximize delivery efficiency, accuracy and plan quality. Methods: 4 GBM patients, with a prescription dose of 59.4 Gy or 60 Gy, were evaluated using the 4π algorithm using 20 beams. The MLC calculation utilized a least square minimization of the dose distribution, with an anisotropic total variation regularization term to encourage piecewise continuity in the fluence maps. Transforming the fluence to the dose domain required multiplying the fluence with a sparse matrix. Exploiting this property made it feasible to solve the problem using CVX, a MATLAB-based convex modeling framework. The fluence was stratified into even step sizes, and the MLC segments, limited to 300, were calculated. The patients studied were replanned using Eclipse with the same beam angles. Results: Compared to the original 4π plan, the stratified 4π plan increased the maximum/mean dose for, in Gy, by 1.0/0.0 (brainstem), 0.5/0.2 (chiasm), 0.0/0.0 (spinal cord), 1.9/0.3 (L eye), 0.7/0.2 (R eye), 0.4/0.4 (L lens), 0.3/0.3 (R lens), 1.0/0.8 (L Optical Nerve), 0.5/0.3 (R Optical Nerve), 0.3/0.2 (L Cochlea), 0.1/0.1 (R Cochlea), 4.6/0.2 (brain), 2.4/0.1 (brain-PTV), 5.1/0.9 (PTV). Compared to Eclipse, which generated an average of 607 segments, the stratified plan reduced (−) or increased (+) the maximum/mean dose, in Gy, by −10.2/−4.1 (brainstem), −10.5/−8.9 (chiasm), +0.0/−0.1 (spinal cord), −4.9/−3.4 (L eye), −4.1/−2.5 (R eye), −2.8/−2.7 (L lens), −2.1/−1.9 (R lens), −7.6/−6.5 (L Optical Nerve), −8.9/−6.1 (R Optical Nerve), −1.3/−1.9 (L Cochlea), −1.8/−1.8 (R Cochlea), +1.7/−2.1 (brain), +3.2/−2.6 (brain-PTV), +1.8/+0.3 Gy (PTV. The stratified plan was also more homogeneous in the PTV. Conclusion: This novel solver can transform complicated fluence maps into significantly fewer deliverable MLC segments than the commercial system while achieving superior dosimetry. Funding support partially contributed by Varian.

  16. TU-C-BRE-06: Effect of Implementing In-House Treatment Couch Model On Patient Specific QA for Pinnacle SmartArc Treatment Plans

    SciTech Connect (OSTI)

    Ellis, A; Jacqmin, D; McDonald, D; Peng, J; Koch, N; Ashenafi, M; Vanek, K

    2014-06-15

    Purpose: Failure to model the treatment couch during VMAT QA planar dose calculation may Result in discrepancies between measured and calculated dose. These discrepancies are due to beam attenuation by the treatment couch that is not included in dose calculation. This work evaluates effects of accounting for this attenuation on patient specific VMAT QA results using an in-house created Varian Exact couch model in Pinnacl Methods: Patient specific VMAT QA results for 13 Pinnacle SmartArc plans generated for treatment on a Varian iX accelerator were studied. These plans included 3 treatment sites (7 H'N, 5 brain, 1 prostate). A Pinnacle model for Varian Exact couch was created in-house to replace the CT simulator couch. Composite arc planar doses were calculated with no couch present (NC) and with the Exact couch model (CM) in place for each plan. QA measurements were taken using IBA Matrixx Evolution ion chamber array set up in IBA MultiCube and were compared to each planar dose. Gamma passing criteria of both 3%/3mm and 2%/2mm tolerances were used. Results: Over all treatment sites, increases in gamma passing rates from NC to CM ranged from -0.4% to +27.3% at 3%/3mm and +0.1% to +30.5% at 2%/2mm. Mean increases in passing rates were +3.7% and +5.3% for 3%/3mm and 2%/2mm tolerances, respectively. Site-specific mean increases (NC to CM) in gamma passing rates were +4.4%, +3.4%, +0.4% (3%/3mm tolerance) and +6.9%, +3.7%, and +2.9% at (2%/2mm tolerance) for H'N, brain, and prostate, respectively. Conclusion: Results support use of a couch model when generating planar dose for patient specific VMAT QA analysis. The improvements were most noticeable at 2%/2mm tolerance and for the H'N and brain sites. Eliminating treatment couch beam attenuation as a source of discrepancy in QA measurements may improve the ability to recognize otherwise masked delivered dose errors.

  17. TU-C-17A-04: BEST IN PHYSICS (THERAPY) - A Supervised Framework for Automatic Contour Assessment for Radiotherapy Planning of Head- Neck Cancer

    SciTech Connect (OSTI)

    Chen, H; Kavanaugh, J; Tan, J; Dolly, S; Gay, H; Thorstad, W; Anastasio, M; Altman, M; Mutic, S; Li, H

    2014-06-15

    Purpose: Precise contour delineation of tumor targets and critical structures from CT simulations is essential for accurate radiotherapy (RT) treatment planning. However, manual and automatic delineation processes can be error prone due to limitations in imaging techniques and individual anatomic variability. Tedious and laborious manual verification is hence needed. This study develops a general framework for automatically assessing RT contours for head-neck cancer patients using geometric attribute distribution models (GADMs). Methods: Geometric attributes (centroid and volume) were computed from physician-approved RT contours of 29 head-neck patients. Considering anatomical correlation between neighboring structures, the GADM for each attribute was trained to characterize intra- and interpatient structure variations using principal component analysis. Each trained GADM was scalable and deformable, but constrained by the principal attribute variations of the training contours. A new hierarchical model adaptation algorithm was utilized to assess the RT contour correctness for a given patient. Receiver operating characteristic (ROC) curves were employed to evaluate and tune system parameters for the training models. Results: Experiments utilizing training and non-training data sets with simulated contouring errors were conducted to validate the framework performance. Promising assessment results of contour normality/abnormality for the training contour-based data were achieved with excellent accuracy (0.99), precision (0.99), recall (0.83), and F-score (0.97), while corresponding values of 0.84, 0.96, 0.83, and 0.9 were achieved for the non-training data. Furthermore, the areas under the ROC curves were above 0.9, validating the accuracy of this test. Conclusion: The proposed framework can reliably identify contour normality/abnormality based upon intra- and inter-structure constraints derived from clinically-approved contours. It also allows physicians to analytically determine the system parameters to fit various clinic requirements (e.g. as-low-as-possible false positives). It has great potential for improving RT work flow. More geometric attributes and training sets will be investigated to improve framework performance in the future.

  18. TU-C-12A-05: Repeatability Study of Reduced Field-Of-View Diffusion-Weighted MRI On Human Thyroid Gland

    SciTech Connect (OSTI)

    Shukla-Dave, A; Lu, Y; Hatzoglou, V; Stambuk, H; Mazaheri, Y; Banerjee, S; Shankaranarayanan, A; Deasy, J

    2014-06-15

    Purpose: To investigate the repeatability of reduced field-of-view diffusion-weighted imaging (rFOV DWI) in quantifying apparent diffusion coefficients (ADCs) for human thyroid glands in a clinical setting. Methods: Nine healthy human volunteers were enrolled and underwent 3T MRI exams. For each volunteer, 3 longitudinal exams (2 weeks apart) with 2 repetitive sessions within each exam, including rFOV and conventional full field-of-view (fFOV) DWI scans, were performed. In the acquired DWI images, a fixed-size region of interest (ROI; diameter=8mm) was placed on thyroid glands to calculate ADC. ADC was calculated using a monoexponential function with a noise correction scheme. The repeatability of ADC was assessed by using coefficient variation (CV) across sessions or exams, which was defined to be: r = 1-CV, 0 < r < 1, where CV=STD/m, STD is the standard deviation of ADC, and m is the average of ADC across sessions or exams. An experienced radiologist assessed and scored rFOV and fFOV DW images based on image characteristics (1, nondiagnostic; 2, poor; 3, satisfactory; 4, good; and 5, excellent).Analysis of variance (ANOVA) was performed to compare ADC values, CV of ADC, repeatability of ADC across sessions and exams, and radiologic scores between rFOV and fFOV DWI techniques. Results: There was no significant difference in ADC values across sessions and exams either in rFOV or fFOV DWI. The average CVs of both rFOV and fFOV DWI were less than 13%. The repeatability of ADC measurement between rFOV and fFOV DWI was not significantly different. The overall image quality was significantly higher with rFOV DWI than with fFOV DWI. Conclusion: This study suggested that ADCs from both rFOV and fFOV DWI were repeatable, but rFOV DWI had superior imaging quality for human thyroid glands in a clinical setting.

  19. TU-F-12A-04: Differential Radiation Avoidance of Functional Liver Regions Defined by 99mTc-Sulfur Colloid SPECT/CT with Proton Therapy

    SciTech Connect (OSTI)

    Bowen, S; Miyaoka, R; Kinahan, P; Sandison, G; Vesselle, H; Nyflot, M; Apisarnthanarax, S; Saini, J; Wong, T

    2014-06-15

    Purpose: Radiotherapy for hepatocellular carcinoma patients is conventionally planned without consideration of spatial heterogeneity in hepatic function, which may increase risk of radiation-induced liver disease. Pencil beam scanning (PBS) proton radiotherapy (pRT) plans were generated to differentially decrease dose to functional liver volumes (FLV) defined on [{sup 99m}Tc]sulfur colloid (SC) SPECT/CT images (functional avoidance plans) and compared against conventional pRT plans. Methods: Three HCC patients underwent SC SPECT/CT scans for pRT planning acquired 15 min post injection over 24 min. Images were reconstructed with OSEM following scatter, collimator, and exhale CT attenuation correction. Functional liver volumes (FLV) were defined by liver:spleen uptake ratio thresholds (43% to 90% maximum). Planning objectives to FLV were based on mean SC SPECT uptake ratio relative to GTV-subtracted liver and inversely scaled to mean liver dose of 20 Gy. PTV target coverage (V{sub 95}) was matched between conventional and functional avoidance plans. PBS pRT plans were optimized in RayStation for single field uniform dose (SFUD) and systematically perturbed to verify robustness to uncertainty in range, setup, and motion. Relative differences in FLV DVH and target dose heterogeneity (D{sub 2}-D{sub 98})/D50 were assessed. Results: For similar liver dose between functional avoidance and conventional PBS pRT plans (D{sub mean}?5% difference, V{sub 18Gy}?1% difference), dose to functional liver volumes were lower in avoidance plans but varied in magnitude across patients (FLV{sub 70%max} D{sub mean}?26% difference, V{sub 18Gy}?8% difference). Higher PTV dose heterogeneity in avoidance plans was associated with lower functional liver dose, particularly for the largest lesion [(D{sub 2}-D{sub 98})/D{sub 50}=13%, FLV{sub 90%max}=50% difference]. Conclusion: Differential avoidance of functional liver regions defined on sulfur colloid SPECT/CT is feasible with proton therapy. The magnitude of benefit appears to be patient specific and dependent on tumor location, size, and proximity to functional volumes. Further investigation in a larger cohort of patients may validate the clinical utility of functional avoidance planning of HCC radiotherapy.

  20. TU-C-BRE-05: Clinical Implications of AAA Commissioning Errors and Ability of Common Commissioning ' Credentialing Procedures to Detect Them

    SciTech Connect (OSTI)

    McVicker, A; Oldham, M; Yin, F; Adamson, J

    2014-06-15

    Purpose: To test the ability of the TG-119 commissioning process and RPC credentialing to detect errors in the commissioning process for a commercial Treatment Planning System (TPS). Methods: We introduced commissioning errors into the commissioning process for the Anisotropic Analytical Algorithm (AAA) within the Eclipse TPS. We included errors in Dosimetric Leaf Gap (DLG), electron contamination, flattening filter material, and beam profile measurement with an inappropriately large farmer chamber (simulated using sliding window smoothing of profiles). We then evaluated the clinical impact of these errors on clinical intensity modulated radiation therapy (IMRT) plans (head and neck, low and intermediate risk prostate, mesothelioma, and scalp) by looking at PTV D99, and mean and max OAR dose. Finally, for errors with substantial clinical impact we determined sensitivity of the RPC IMRT film analysis at the midpoint between PTV and OAR using a 4mm distance to agreement metric, and of a 7% TLD dose comparison. We also determined sensitivity of the 3 dose planes of the TG-119 C-shape IMRT phantom using gamma criteria of 3% 3mm. Results: The largest clinical impact came from large changes in the DLG with a change of 1mm resulting in up to a 5% change in the primary PTV D99. This resulted in a discrepancy in the RPC TLDs in the PTVs and OARs of 7.1% and 13.6% respectively, which would have resulted in detection. While use of incorrect flattening filter caused only subtle errors (<1%) in clinical plans, the effect was most pronounced for the RPC TLDs in the OARs (>6%). Conclusion: The AAA commissioning process within the Eclipse TPS is surprisingly robust to user error. When errors do occur, the RPC and TG-119 commissioning credentialing criteria are effective at detecting them; however OAR TLDs are the most sensitive despite the RPC currently excluding them from analysis.

  1. TU-F-17A-08: The Relative Accuracy of 4D Dose Accumulation for Lung Radiotherapy Using Rigid Dose Projection Versus Dose Recalculation On Every Breathing Phase

    SciTech Connect (OSTI)

    Lamb, J; Lee, C; Tee, S; Lee, P; Iwamoto, K; Low, D; Valdes, G; Robinson, C

    2014-06-15

    Purpose: To investigate the accuracy of 4D dose accumulation using projection of dose calculated on the end-exhalation, mid-ventilation, or average intensity breathing phase CT scan, versus dose accumulation performed using full Monte Carlo dose recalculation on every breathing phase. Methods: Radiotherapy plans were analyzed for 10 patients with stage I-II lung cancer planned using 4D-CT. SBRT plans were optimized using the dose calculated by a commercially-available Monte Carlo algorithm on the end-exhalation 4D-CT phase. 4D dose accumulations using deformable registration were performed with a commercially available tool that projected the planned dose onto every breathing phase without recalculation, as well as with a Monte Carlo recalculation of the dose on all breathing phases. The 3D planned dose (3D-EX), the 3D dose calculated on the average intensity image (3D-AVE), and the 4D accumulations of the dose calculated on the end-exhalation phase CT (4D-PR-EX), the mid-ventilation phase CT (4D-PR-MID), and the average intensity image (4D-PR-AVE), respectively, were compared against the accumulation of the Monte Carlo dose recalculated on every phase. Plan evaluation metrics relating to target volumes and critical structures relevant for lung SBRT were analyzed. Results: Plan evaluation metrics tabulated using 4D-PR-EX, 4D-PR-MID, and 4D-PR-AVE differed from those tabulated using Monte Carlo recalculation on every phase by an average of 0.140.70 Gy, - 0.110.51 Gy, and 0.000.62 Gy, respectively. Deviations of between 8 and 13 Gy were observed between the 4D-MC calculations and both 3D methods for the proximal bronchial trees of 3 patients. Conclusions: 4D dose accumulation using projection without re-calculation may be sufficiently accurate compared to 4D dose accumulated from Monte Carlo recalculation on every phase, depending on institutional protocols. Use of 4D dose accumulation should be considered when evaluating normal tissue complication probabilities as well as in clinical situations where target volumes are directly inferior to mobile critical structures.

  2. TU-A-9A-05: First Experimental Demonstration of the Anisotropic Detection Principle in X-Ray Fluorescence Computed Tomography

    SciTech Connect (OSTI)

    Ahmad, M; Bazalova, M; Fahrig, R; Xing, L

    2014-06-15

    Purpose: To improve the sensitivity of X-ray fluorescence computed tomography (XFCT) for in vivo molecular imaging. Is the maximum sensitivity achieved with an isotropic (4π) detector configuration? We prove that this is not necessarily true, and that a greater sensitivity is possible with anisotropic detector configuration. Methods: An XFCT imaging system was constructed consisting of 1) a collimated pencil beam x-ray source using a fluoroscopy grade x-ray tube; 2) a CdTe x-ray photon counting detector to detect fluorescent x-rays; and 3) a rotation/translation stage for tomographic imaging. We created a 6.5-cm diameter water phantom with 2-cm inserts of low gold concentration (0.25%–1%) to simulate tumors targeted by gold nano-particles. The placement of x-ray fluorescence detector were chosen to minimize scatter x-rays. XFCT imaging was performed at three different detector positions (60°, 90°, 145°) to determine the impact of forward-scatter, side-scatter, and back-scatter on imaging performance. The three data sets were also combined to estimate the imaging performance with an isotropic detector. Results: The highest imaging performance was achieved when the XF detector was in the backscatter 145° configuration. The signal-to-noise ratio (SNR) was 5.5 for the 0.25% gold concentration compared to SNRs of 1.4, 0, and 2.4 for 60°, 90°, and combined (60°+90°+145°) datasets. Only the 145° detector arrangement alone could detect the 0.25% concentration. The imaging dose was 14 mGy for each detector arrangement experiment. Conclusion: This study experimentally proves, for the fist time, the Anisotropic Detection Principle in XF imaging, which holds that optimized anisotropic x-ray fluorescence detection provides greater sensitivity than isotropic detection. The optimized detection arrangement was used to improve the sensitivity of the XFCT experiment. The achieved XFCT sensitivity is the highest ever for a phantom at least this large using a benchtop x-ray source, which is an important step toward clinical XFCT molecular imaging. This work was supported by the NCI fellowship grant R25T-CA118681 and by the NIH (1R01-EB016777) and NIBIB (1K99-EB016059)

  3. Fermilab | TUFTE Exhibit | April 12-June 26, 2014 | Artwork

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    or email georgia@fnal.gov for more information. All images courtesy Edward Tufte. thumb Hi-res Med-res thumb Hi-res Med-res thumb Hi-res Med-res thumb Hi-res Med-res thumb Hi-res...

  4. EA-1472: Commercial Demonstration fo the Low Nox Burner/Separated Over-Fire Air (LNB/SOFA) Integration System Emission Reduction Technology, Holcolm Station, Sunflower Electric Power Corporation Finnety County, Kansas

    Broader source: Energy.gov [DOE]

    The DOE has prepared an Environmental Assessment (EA), to analyze the potential impacts of the commercial application of the Low-NOx Burner/Separated Over-Fire Air (LNB/SOFA) integration system to achieve nitrogen oxide (NOx) emissions reduction at Sunflower’s Holcomb Unit No. 1 (Holcomb Station), located near Garden City, in Finney County, Kansas. The Holcomb Station would be modified in three distinct phases to demonstrate the synergistic effect of layering NOx control technologies.

  5. Solar Technology Validation Project - RES Americas: Cooperative Research and Development Final Report, CRADA Number CRD-09-367-11

    SciTech Connect (OSTI)

    Wilcox, S.

    2013-08-01

    Under this Agreement, NREL will work with Participant to improve concentrating solar power system performance characterizations. This work includes, but is not limited to, research and development of methods for acquiring renewable resource characterization information using site-specific measurements of solar radiation and meteorological conditions; collecting system performance data; and developing tools for improving the design, installation, operation, and maintenance of solar energy conversion systems. This work will be conducted at NREL and Participant facilities.

  6. Rocky Mountain Research Station and LANL build

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Conventional Gasoline Blend. Comp. Fuel Ethanol (Renewable) Biomass-Based Diesel (Renewable) Distillate Fuel Oil Distillate F.O., 15 ppm and under Distillate F.O., 15 to 500 ppm Distillate F.O., Greater than 500 ppm Distillate F.O., 501 to 2000 ppm Distillate F.O., Greater than 2000 ppm Kerosene Finished Aviation Gasoline Kerosene-Type Jet Fuel Special Naphthas Residual Fuel Oil Residual F.O., Less than 0.31% Sulfur Residual F.O., 0.31 to 1% Sulfur Residual F.O., Greater than 1% Sulfur Naphtha

  7. Advanced, Energy-Efficient Hybrid Membrane System for Industrial...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of waste heat Synergistic coupling of FO (forward osmosis) and MD (membrane distillation) FO (osmotically driven process): Pretreatment for MD MD (thermally driven ...

  8. Rocky Mountain (PADD 4) Total Crude Oil and Products Imports

    U.S. Energy Information Administration (EIA) Indexed Site

    Conventional Gasoline Blend. Comp. Fuel Ethanol (Renewable) Biomass-Based Diesel (Renewable) Distillate Fuel Oil Distillate F.O., 15 ppm and under Distillate F.O., 15 to 500 ppm Distillate F.O., Greater than 500 ppm Distillate F.O., 501 to 2000 ppm Distillate F.O., Greater than 2000 ppm Kerosene Finished Aviation Gasoline Kerosene-Type Jet Fuel Special Naphthas Residual Fuel Oil Residual F.O., Less than 0.31% Sulfur Residual F.O., 0.31 to 1% Sulfur Residual F.O., Greater than 1% Sulfur Naphtha

  9. Rocky Mountain (PADD 4) Total Crude Oil and Products Imports

    U.S. Energy Information Administration (EIA) Indexed Site

    Conventional Gasoline Blend. Comp. Fuel Ethanol (Renewable) Biomass-Based Diesel (Renewable) Distillate Fuel Oil Distillate F.O., 15 ppm and under Distillate F.O., 15 to 500 ppm Distillate F.O., Greater than 500 ppm Distillate F.O., 501 to 2000 ppm Distillate F.O., Greater than 2000 ppm Kerosene Finished Aviation Gasoline Kerosene-Type Jet Fuel Special Naphthas Residual Fuel Oil Residual F.O., Less than 0.31% Sulfur Residual F.O., 0.31 to 1% Sulfur Residual F.O., Greater than 1% Sulfur Naphtha

  10. Energy requirements of the switchable polarity solvent forward...

    Office of Scientific and Technical Information (OSTI)

    (SPS-FO) water purification process Citation Details In-Document Search Title: Energy requirements of the switchable polarity solvent forward osmosis (SPS-FO) water purification ...

  11. TU-A-12A-12: Improved Airway Measurement Accuracy for Low Dose Quantitative CT (qCT) Using Statistical (ASIR), at Reduced DFOV, and High Resolution Kernels in a Phantom and Swine Model

    SciTech Connect (OSTI)

    Yadava, G; Imai, Y; Hsieh, J

    2014-06-15

    Purpose: Quantitative accuracy of Iodine Hounsfield Unit (HU) in conventional single-kVp scanning is susceptible to beam-hardening effect. Dual-energy CT has unique capabilities of quantification using monochromatic CT images, but this scanning mode requires the availability of the state-of-the-art CT scanner and, therefore, is limited in routine clinical practice. Purpose of this work was to develop a beam-hardening-correction (BHC) for single-kVp CT that can linearize Iodine projections at any nominal energy, apply this approach to study Iodine response with respect to keV, and compare with dual-energy based monochromatic images obtained from material-decomposition using 80kVp and 140kVp. Methods: Tissue characterization phantoms (Gammex Inc.), containing solid-Iodine inserts of different concentrations, were scanned using GE multi-slice CT scanner at 80, 100, 120, and 140 kVp. A model-based BHC algorithm was developed where Iodine was estimated using re-projection of image volume and corrected through an iterative process. In the correction, the re-projected Iodine was linearized using a polynomial mapping between monochromatic path-lengths at various nominal energies (40 to 140 keV) and physically modeled polychromatic path-lengths. The beam-hardening-corrected 80kVp and 140kVp images (linearized approximately at effective energy of the beam) were used for dual-energy material-decomposition in Water-Iodine basis-pair followed by generation of monochromatic images. Characterization of Iodine HU and noise in the images obtained from singlekVp with BHC at various nominal keV, and corresponding dual-energy monochromatic images, was carried out. Results: Iodine HU vs. keV response from single-kVp with BHC and dual-energy monochromatic images were found to be very similar, indicating that single-kVp data may be used to create material specific monochromatic equivalent using modelbased projection linearization. Conclusion: This approach may enable quantification of Iodine contrast enhancement and potential reduction in injected contrast without using dual-energy scanning. However, in general, dual-energy scanning has unique value in material characterization and quantification, and its value cannot be discounted. GE Healthcare Employee.

  12. TU-F-BRE-07: In Vivo Neutron Detection in Patients Undergoing Stereotactic Ablative Radiotherapy (SABR) for Primary Kidney Cancer Using 6Li and 7Li Enriched TLD Pairs

    SciTech Connect (OSTI)

    Lonski, P; Kron, T; Franich, R; Keehan, S; Siva, S; Taylor, M

    2014-06-15

    Purpose: Stereotactic ablative radiotherapy (SABR) for primary kidney cancer often involves the use of high-energy photons combined with a large number of monitor units. While important for risk assessment, the additional neutron dose to untargeted healthy tissue is not accounted for in treatment planning. This work aims to detect out-of-field neutrons in vivo for patients undergoing SABR with high-energy (>10 MV) photons and provides preliminary estimates of neutron effective dose. Methods: 3 variations of high-sensitivity LiF:Mg,Cu,P thermoluminescent dosimeter (TLD) material, each with varying {sup 6}Li / {sup 7}Li concentrations, were used in custom-made Perspex holders for in vivo measurements. The variation in cross section for thermal neutrons between Li isotopes was exploited to distinguish neutron from photon signal. Measurements were made out-of-field for 7 patients, each undergoing 3D-conformal SABR treatment for primary kidney cancer on a Varian 21iX linear accelerator. Results: In vivo measurements show increased signal for the {sup 6}Li enriched material for patients treated with 18 MV photons. Measurements on one SABR patient treated using only 6 MV showed no difference between the 3 TLD materials. The out-of-field photon signal decreased exponentially with distance from the treatment field. The neutron signal, taken as the difference between {sup 6}Li enriched and {sup 7}Li enriched TLD response, remains almost constant up to 50 cm from the beam central axis. Estimates of neutron effective dose from preliminary TLD calibration suggest between 10 and 30 mSv per 1000 MU delivered at 18 MV for the 7 patients. Conclusion: TLD was proven to be a useful tool for the purpose of in vivo neutron detection at out-of-field locations. Further work is required to understand the relationship between TL signal and neutron dose. Dose estimates based on preliminary TLD calibration in a neutron beam suggest the additional neutron dose was <30 mSv per 1000 MU at 18 MV.

  13. TU-F-BRE-03: Application of a Novel Mass-Density Compensation Optimization Method to Improve the Response of a Liquid-Filled Ionization Chamber in Nonstandard Fields

    SciTech Connect (OSTI)

    Kamio, Y; Bouchard, H

    2014-06-15

    Purpose: To improve the response of the microLion detector (PTW 31018) in small field conditions by optimizing the density of the detector's non-sensitive components using a novel method based on the detector's dose response function. Methods: The central values h(0,0) of the perturbation functions for the microLion detector and a volume of water equivalent to its sensitive volume were calculated using the Monte Carlo user code egs-chamber by scoring the dose absorbed by a 6 MV photon pencil beam incident on their centroids. Values of h(0,0) were plotted as a function of the density of the microLion's graphite electrode with the detector placed in the axial orientation. The optimized density was found by finding the minimal value of h(0,0). Results: A density of 1.37 g/cm3 was found to minimize the perturbation function of the microLion detector. The modified microLion's response was then evaluated in small square fields with sides in the range of 5 – 40 mm and found to be consistent with highly watere-quivalent detectors such as a scintillating detector (Exradin W1) and a generic alanine detector in both axial and radial orientations. Conclusion: This work illustrates a novel method which can used to optimize the design of radiation detectors in small fields. This method should also work with other optimization parameters (e.g. thickness of electrode). Density-compensated detectors have the potential to eliminate the need to evaluate nonstandard field correction factors as described by the IAEA-AAPM formalism (Alfonso et al.) and simplify future dosimetry protocols for SRS/SBRT modalities. Finally, we also expect an improvement in the response of density-compensated detectors for composite IMRT fields.

  14. Midwest Regional Carbon Sequestration Partnership-Validation Phase

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Fuel Ethanol (Renewable) Biomass-Based Diesel (Renewable) Other Renewable Diesel Other Renewable Fuels Distillate Fuel Oil Distillate F.O., 15 ppm and under Distillate F.O., 15 to 500 ppm Distillate F.O., Greater than 500 ppm Distillate F.O., 501 to 2000 ppm Distillate F.O., Greater than 2000 ppm Kerosene Finished Aviation Gasoline Aviation Gasoline Blending Components Kerosene-Type Jet Fuel Special Naphthas Residual Fuel Oil Residual F.O., Less than 0.31% Sulfur Residual F.O., 0.31 to 1% Sulfur

  15. Gulf Coast (PADD 3) Total Crude Oil and Products Imports

    U.S. Energy Information Administration (EIA) Indexed Site

    MTBE (Oxygenate) Other Oxygenates Fuel Ethanol (Renewable) Biomass-Based Diesel (Renewable) Other Renewable Diesel Distillate Fuel Oil Distillate F.O., 15 ppm and under Distillate F.O., 15 to 500 ppm Distillate F.O., Greater than 500 ppm Distillate F.O., 501 to 2000 ppm Distillate F.O., Greater than 2000 ppm Kerosene Finished Aviation Gasoline Aviation Gasoline Blending Components Kerosene-Type Jet Fuel Special Naphthas Residual Fuel Oil Residual F.O., Less than 0.31% Sulfur Residual F.O., 0.31

  16. Midwest (PADD 2) Total Crude Oil and Products Imports

    U.S. Energy Information Administration (EIA) Indexed Site

    Fuel Ethanol (Renewable) Biomass-Based Diesel (Renewable) Other Renewable Diesel Other Renewable Fuels Distillate Fuel Oil Distillate F.O., 15 ppm and under Distillate F.O., 15 to 500 ppm Distillate F.O., Greater than 500 ppm Distillate F.O., 501 to 2000 ppm Distillate F.O., Greater than 2000 ppm Kerosene Finished Aviation Gasoline Aviation Gasoline Blending Components Kerosene-Type Jet Fuel Special Naphthas Residual Fuel Oil Residual F.O., Less than 0.31% Sulfur Residual F.O., 0.31 to 1% Sulfur

  17. Gulf Coast (PADD 3) Total Crude Oil and Products Imports

    U.S. Energy Information Administration (EIA) Indexed Site

    MTBE (Oxygenate) Other Oxygenates Fuel Ethanol (Renewable) Biomass-Based Diesel (Renewable) Other Renewable Diesel Distillate Fuel Oil Distillate F.O., 15 ppm and under Distillate F.O., 15 to 500 ppm Distillate F.O., Greater than 500 ppm Distillate F.O., 501 to 2000 ppm Distillate F.O., Greater than 2000 ppm Kerosene Finished Aviation Gasoline Aviation Gasoline Blending Components Kerosene-Type Jet Fuel Special Naphthas Residual Fuel Oil Residual F.O., Less than 0.31% Sulfur Residual F.O., 0.31

  18. Midwest (PADD 2) Total Crude Oil and Products Imports

    U.S. Energy Information Administration (EIA) Indexed Site

    Fuel Ethanol (Renewable) Biomass-Based Diesel (Renewable) Other Renewable Diesel Other Renewable Fuels Distillate Fuel Oil Distillate F.O., 15 ppm and under Distillate F.O., 15 to 500 ppm Distillate F.O., Greater than 500 ppm Distillate F.O., 501 to 2000 ppm Distillate F.O., Greater than 2000 ppm Kerosene Finished Aviation Gasoline Aviation Gasoline Blending Components Kerosene-Type Jet Fuel Special Naphthas Residual Fuel Oil Residual F.O., Less than 0.31% Sulfur Residual F.O., 0.31 to 1% Sulfur

  19. Fermilab | Tevatron | Media

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Med Res | Hi Res Med Res | Hi Res Accelerator operators working 24-hours-a-day maintain a "sweet spot" level of protons and antiprotons and steer them through a chain of seven ...

  20. Official AEF Logos | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    ... Web, Video, and Presentation Usage (RGB): Low-res .JPG .jpg file (20KB) | High-res .JPG ... Web, Video, and Presentation Usage (RGB): Low-res .JPG .jpg file (13KB) | High-res .JPG ...

  1. Fermilab | Photowalk | 2015 Photowalk: Winning Images

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    here. Top Three Photos thumb First place photo by Mike Baker, Bolingbrook, IL Hi-res Med-res thumb Second place photo by Mike Baker, Bolingbrook, IL Hi-res Med-res thumb...

  2. Fermilab | Photowalk | 2012 Winning Images

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    information. Top Five Photos thumb First place photo by Stan Kirschner, Mundelein, IL Hi-res Med-res thumb Second place photo by Brian Schultz, Naperville, IL Hi-res Med-res...

  3. West Coast (PADD 5) Total Crude Oil and Products Imports

    U.S. Energy Information Administration (EIA) Indexed Site

    Reformulated Gasoline Blend. Comp. Conventional Gasoline Blend. Comp. MTBE (Oxygenate) Other Oxygenates Fuel Ethanol (Renewable) Biomass-Based Diesel (Renewable) Other Renewable Diesel Distillate Fuel Oil Distillate F.O., 15 ppm and under Distillate F.O., 15 to 500 ppm Distillate F.O., Greater than 500 ppm Distillate F.O., 501 to 2000 ppm Distillate F.O., Greater than 2000 ppm Kerosene Finished Aviation Gasoline Aviation Gasoline Blending Components Kerosene-Type Jet Fuel Special Naphthas

  4. West Virginia Native Selected to Present at the Council for Chemical Research Me

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Reformulated Gasoline Blend. Comp. Conventional Gasoline Blend. Comp. MTBE (Oxygenate) Other Oxygenates Fuel Ethanol (Renewable) Biomass-Based Diesel (Renewable) Other Renewable Diesel Distillate Fuel Oil Distillate F.O., 15 ppm and under Distillate F.O., 15 to 500 ppm Distillate F.O., Greater than 500 ppm Distillate F.O., 501 to 2000 ppm Distillate F.O., Greater than 2000 ppm Kerosene Finished Aviation Gasoline Aviation Gasoline Blending Components Kerosene-Type Jet Fuel Special Naphthas

  5. Indiana Humanities Council Request for the Indianapolis Energy Conversion Inst. For Phase I of the Indianapolis Energy Conservation Res Initiative also called the smartDESKTOP Initiative

    SciTech Connect (OSTI)

    Keller, John B.

    2007-12-06

    The smartDESKTOP Initiative at the Indiana Humanities Council received critical support in building and delivering a digital desktop for Indiana educators through the Department of Energy Grant DE-FG02-06ER64282. During the project period September 2006 through October of 2007, the number of Indiana educators with accounts on the smartDESKTOP more than tripled from under 2,000 to more than 7,000 accounts. An external review of the project conducted for the purposes of understanding the impact of the service in Indiana schools revealed that the majority of respondents felt that using the smartDESKTOP did reduce the time they spent managing paper. The same study revealed the challenges of implementing a digital desktop meant to help teachers leverage technology to improve their teaching and ultimately student learning. The most significant outcome of this project is that the Indiana Department of Education expressed interest in assuming responsibility for sustaining this project. The transition of the smartDESKTOP to the Indiana Department of Education was effective on November 1, 2007.

  6. East Coast (PADD 1) Total Crude Oil and Products Imports

    U.S. Energy Information Administration (EIA) Indexed Site

    MTBE (Oxygenate) Other Oxygenates Fuel Ethanol (Renewable) Biomass-Based Diesel (Renewable) Other Renewable Diesel Other Renewable Fuels Distillate Fuel Oil Distillate F.O., 15 ppm and under Distillate F.O., 15 to 500 ppm Distillate F.O., Greater than 500 ppm Distillate F.O., 501 to 2000 ppm Distillate F.O., Greater than 2000 ppm Kerosene Finished Aviation Gasoline Aviation Gasoline Blending Components Kerosene-Type Jet Fuel Special Naphthas Residual Fuel Oil Residual F.O., Less than 0.31%

  7. Energy requirements of the switchable polarity solvent forward osmosis

    Office of Scientific and Technical Information (OSTI)

    (SPS-FO) water purification process (Journal Article) | SciTech Connect Journal Article: Energy requirements of the switchable polarity solvent forward osmosis (SPS-FO) water purification process Citation Details In-Document Search Title: Energy requirements of the switchable polarity solvent forward osmosis (SPS-FO) water purification process A model was developed to estimate the process energy requirements of a switchable polarity solvent forward osmosis (SPS FO) system for water

  8. BPA-2012-00676-FOIA Request

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    *** FO1.A OFFICE TILTS DATE: DUE DATE: Name: Francisco Carvalho Organization: University Professor Address: Phone: FAX: Email: Description of...

  9. MEMORANDUM FOR JAMES A. HUTTON ACTING DEPUTY ASSISTANT SECRETARY...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    July 12, 2011 MEMORANDUM FOR JAMES A. HUTTON ACTING DEPUTY ASSISTANT SECRETARY FOR SAFETY AND SECURITY PROGRAM ENVIRONMENTALMANAGEMENT . FROM: INES R. TRIA Y t::U1)...

  10. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    Institute of Materials Science, TU Dresden, D-01062 Dresden" ... of Energy's (DOE) Nuclear Energy (NE) Radioisotope ... Fernald Environmental Management Project, OH (United ...

  11. ARM - Datastreams - fslruc60

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Atmospheric pressure Tp Atmospheric temperature Tpot Horizontal wind Tu Horizontal wind Tv Atmospheric pressure cp Atmospheric pressure p Horizontal wind u Horizontal wind v...

  12. Comparative Genome Structure, Secondary Metabolite, and Effector...

    Office of Scientific and Technical Information (OSTI)

    Manning, Viola A.; Dhillon, Braham; Tu, Zheng Jin; Steffenson, Brian J.; Salamov, Asaf; Sun, Hui; Lowry, Steve; LaButti, Kurt; Han, James; Copeland, Alex; Lindquist, Erika; Barry,...

  13. "Title","Creator/Author","Publication Date","OSTI Identifier...

    Office of Scientific and Technical Information (OSTI)

    Manning, Viola A.; Dhillon, Braham; Tu, Zheng Jin; Steffenson, Brian J.; Salamov, Asaf; Sun, Hui; Lowry, Steve; LaButti, Kurt; Han, James; Copeland, Alex; Lindquist, Erika; Barry,...

  14. The Chief Information Officer (CIO) at the U

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... TU5.2.16UT TUPeer-to-Peer Technology GuidanceUT ... TUCyber Security Architecture and TechnologyUT ... extensive assessment of the current situation ...

  15. Performance Analysis with Vampir

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    (frank.winkler@tu-dresden.de) Performance Analysis with Vampir Disclaimer Performance tools will not automatically make you code run faster. They help you understand, what your...

  16. Print

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Apaga las luces. Marca la caja. Apaga tu computadora. Usa bombillas de alta eficiencia energtica. Desenchufa los cargadores cuando no estn en uso. Usa luz natural, calor del ...

  17. Print

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    maneras fciles de usar energa en forma inteligente Apaga las luces. Marca la caja. Apaga tu computadora. Usa bombillas de alta eficiencia energtica. Desenchufa los cargadores...

  18. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    ... Correlation of genomic and physiological traits to biofuel yields in Thermoanaerobacter species Phelps, Tommy Joe ; Hemme, Christopher Lee ; Fields, Matthew Wayne ; HE, Qiang ; Tu, ...

  19. Momentum Savings Market Research & Update New Webpage

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    - CAC Water Evap Cooled - - - - 0.00 0.00 PTACHP 0.01 0.01 0.01 0.01 0.01 0.01 Res Dishwasher - - - - - - Res Refrigerators - - - - - - Res Freezers - - - - - 0.61 External Power...

  20. Anisotropic magnetic properties of Dy{sub 6}Cr{sub 4}Al{sub 43...

    Office of Scientific and Technical Information (OSTI)

    Authors: Maurya, Arvind, E-mail: arvindmaurya@tifr.res.in ; Thamizhavel, A., E-mail: arvindmaurya@tifr.res.in ; Dhar, S. K., E-mail: arvindmaurya@tifr.res.in 1 + Show Author ...

  1. Southwestern Public Service Co | Open Energy Information

    Open Energy Info (EERE)

    table contains monthly sales and revenue data for Southwestern Public Service Co (New Mexico). Scroll leftright to see all of the table values. Month RES REV (THOUSAND ) RES...

  2. Fermilab | Press Room | Images

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    When using this material please credit Fermilab. Return to Press Release Med Res | Hi Res Scientists from the CDF and DZero collaborations at DOE's Fermilab have combined...

  3. Fermilab | Press Room | Images

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    When using these images, please credit Fermilab. Return to Press Release Med Res | Hi Res According to the Standard Model of particles and forces, the Higgs mechanism gives...

  4. Fermilab | Press Room | Images

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    using these images, please credit them as specified. Return to Press Release Med Res | Hi Res The Standard Model describes the interactions of the fundamental particle of the...

  5. TU-F-12A-01: Quantitative Non-Linear Compartment Modeling of 89Zr- and 124I- Labeled J591 Monoclonal Antibody Kinetics Using Serial Non-Invasive Positron Emission Tomography Imaging in a Pre-Clinical Human Prostate Cancer Mouse Model

    SciTech Connect (OSTI)

    Fung, EK; Cheal, SM; Chalasani, S; Fareedy, SB; Punzalan, B; Humm, JL; Osborne, JR; Larson, SM; Zanzonico, PB; Otto, B; Bander, NH

    2014-06-15

    Purpose: To examine the binding kinetics of human IgG monoclonal antibody J591 which targets prostate-specific membrane antigen (PSMA) in a pre-clinical mouse cancer model using quantitative PET compartmental analysis of two radiolabeled variants. Methods: PSMA is expressed in normal human prostate, and becomes highly upregulated in prostate cancer, making it a promising therapeutic target. Two forms of J591, radiolabeled with either {sup 89}Zr or {sup 124}I, were prepared. {sup 89}Zr is a radiometal that becomes trapped in the cell upon internalization by the antigen-antibody complex, while radioiodine leaves the cell. Mice with prostate cancer xenografts underwent non-invasive serial imaging on a Focus 120 microPET up to 144 hours post-injection of J591. A non-linear compartmental model describing the binding and internalization of antibody in tumor xenograft was developed and applied to the PET-derived time-activity curves. The antibody-antigen association rate constant (ka), total amount of antigen per gram tumor (Ag-total), internalization rate of antibody-antigen complex, and efflux rate of radioisotope from tumor were fitted using the model. The surface-bound and the internalized activity were also estimated. Results: Values for ka, Ag-total, and internalization rate were found to be similar regardless of radiolabel payload used. The efflux rate, however, was ∼ 9-fold higher for {sup 124}I-J591 than for {sup 89}Zr-J591. Time-dependent surface-bound and internalized radiotracer activity were similar for both radiolabels at early times post-injection, but clearly differed beyond 24 hours. Conclusion: Binding and internalization of J591 to PSMA-expressing tumor xenografts were similar when radiolabeled with either {sup 89}Zr or {sup 124}I payload. The difference in efflux of radioactivity from tumor may be attributable to differential biological fate intracellularly of the radioisotopes. This has great significance for radioimmunotherapy and antibody-drug conjugates. Further exploration using the model will examine binding and radioisotope residence as antibody dose is increased to antigen saturation. The Center for Targeted Radioimmunotherapy and Theranostics, Ludwig Center for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center (MSK), NIH (R25-CA096945). Technical services provided by the MSK Small-Animal Imaging Core Facility were supported by the NIH (R24-CA83084, P30-CA08748, and P50-CA92629; Zanzonico). NCI, Center to Reduce Cancer Health Disparity (R21 CA153177-03; Osborne)

  6. 11-1370.pdf

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Signature on File Signature on File Mr. John Kieling -2- DEC 2 2 2011 bcc: G. Basabilvazo, CBFO *ED S. McCauslin, CBFO ED A. Stone, CBFO ED O. Franco, WTS ED S. Herrick, WTS ED R. Chavez, WTS ED D. Cook, WTS ED E. D'Amico, RES ED J. Haschets, RES ED S. Jones, RES ED R. Kehrman, RES ED S.Kouba, RES ED W. Most, RES ED R. Salness, RES ED RCRA Chronology ED WIPP Operating Record ED Stakeholder Notification ED -ED denotes electronic distribution CBFO:OESH:SEM:ANC:11-1370:UFC 5486.00

  7. Blender Net Production of Finished Motor Gasoline

    U.S. Energy Information Administration (EIA) Indexed Site

    Product: Total Finished Motor Gasoline Reformulated Gasoline Reformulated Blended w/ Fuel Ethanol Reformulated Other Conventional Gasoline Conventional Blended w/ Fuel Ethanol Conventional Blended w/ Fuel Ethanol, Ed55 and Lower Conventional Blended w/ Fuel Ethanol, Greater than Ed55 Conventional Other Finished Aviation Gasoline Kerosene-Type Jet Fuel Kerosene Distillate Fuel Oil Distillate F.O., 15 ppm Sulfur and under Distillate F.O., Greater than 15 ppm to 500 ppm Sulfur Distillate F.O.,

  8. CSV File Documentation: Consumption

    Gasoline and Diesel Fuel Update (EIA)

    Product: Total Finished Motor Gasoline Reformulated Gasoline Reformulated Blended w/ Fuel Ethanol Reformulated Other Conventional Gasoline Conventional Blended w/ Fuel Ethanol Conventional Blended w/ Fuel Ethanol, Ed55 and Lower Conventional Blended w/ Fuel Ethanol, Greater than Ed55 Conventional Other Finished Aviation Gasoline Kerosene-Type Jet Fuel Kerosene Distillate Fuel Oil Distillate F.O., 15 ppm Sulfur and under Distillate F.O., Greater than 15 ppm to 500 ppm Sulfur Distillate F.O.,

  9. -Asymmetric formation (process) of vortex state in permalloy...

    Office of Scientific and Technical Information (OSTI)

    National Institute fo r Materials Science (NIMS), Tukuba 305-0047, Japan The ... Here we show the first direct observation of an asymmetric phenomenon in the formation ...

  10. Tax Credits, Rebates & Savings | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    Rebate Program offers rebates for the removal of old, less efficient lighting products which are replaced with high efficiency technologies. The program is primarily fo......

  11. FY09_Federal_Real_Property_Reporting_Requirements.pdf | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    yReportingRequirements.pdf More Documents & Publications 2013 guidance fo real Property Inventory Reporting FY 2012 Federal Real Property Reporting Requirement Guidance for...

  12. FY 2012 Federal Real Property Reporting Requirement | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Instructions 2012 final.pdf More Documents & Publications 2013 guidance fo real Property Inventory Reporting FY09FederalRealPropertyReportingRequirements.pdf Guidance for...

  13. Advance Patent Waiver W(A)2012-004

    Broader source: Energy.gov [DOE]

    This is a request by GENERAL ELECTRIC GLOBAL REARCH for a DOE Advance patent waiver of domestic and foreign patent rights under agreement DE-FO0007514.

  14. Linux Kernel Error Detection and Correction

    Energy Science and Technology Software Center (OSTI)

    2007-04-11

    EDAC-utils consists fo a library and set of utilities for retrieving statistics from the Linux Kernel Error Detection and Correction (EDAC) drivers.

  15. EA-1472: Finding of No Significant Impact

    Office of Energy Efficiency and Renewable Energy (EERE)

    Commercial Demonstration fo the Low Nox Burner/Separated Over-Fire Air (LNB/SOFA) Integration System Emission Reduction Technology, Holcolm Station, Sunflower Electric Power Corporation Finnety...

  16. Memorandum Summarizing Ex Parte Communication | Department of...

    Office of Environmental Management (EM)

    non-weatherized gas furnaces American Gas Association Memorandum Summarizing Ex Parte Communication ITP Steel: Energy and Environmental Profile fo the U.S. Iron and Steel Industry

  17. Akin Gump STRAUSS HAUER & FELD LLP SCOTT M. HEIMBERG

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    July 15. 2016 HQ~10\ b ~ D\ 1~~ f Akin Gump STRAUSS HAUER & FELD LLP SCOTT M. HEIMBERG 202 887 4085/lax: 202.887.4288 sheimberg@akmgump.com FO lA Officer United States Department of Energy I 000 Independence Avenue, SW Washington, DC 20585 Re: freedom of Information Act Request Dear f-O IA Officer: Thi s is a request under the Freedom or Information Act ("FO f A"). Pursuant to FOIA, 1 request that a copy of documents containing the in fo rmation described below be provided to me. I

  18. Search for: All records | DOE PAGES

    Office of Scientific and Technical Information (OSTI)

    A metastable phase of tin in 3D integrated circuit solder microbumps Liu, Yingxia ; Tamura, Nobumichi ; Kim, Dong Wook ; Gu, Sam ; Tu, K. N. June 2015 , Elsevier Serial snapshot ...

  19. TITLE AUTHORS SUBJECT SUBJECT RELATED DESCRIPTION PUBLISHER AVAILABILI...

    Office of Scientific and Technical Information (OSTI)

    Wang Rui Manning Viola A Dhillon Braham Tu Zheng Jin Steffenson Brian J Salamov Asaf Sun Hui Lowry Steve LaButti Kurt Han James Copeland Alex Lindquist Erika Barry Kerrie...

  20. Hon Hai Precision Industry Co Ltd | Open Energy Information

    Open Energy Info (EERE)

    Co Ltd Place: Tu-Cheng City, Taiwan Zip: 236 Sector: Solar Product: Taiwan-based electronics firm, which is also a manufacturer of solar modules. References: Hon Hai Precision...

  1. Papers Published - April 1, 2001 - March 31, 2002

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... L. Tang, W. B. Tippens, R. E. Tribble, X. L. Tu, L. A. Van Ausdeln, W. H. von Witch, D. Whitehouse, C. Wilkinson, B. Wright, S. C. Wright, Y. Zhang, and K. O. H. Ziock Phys. Rev. ...

  2. 6Li Cross Section

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    p, X) (Current as of 03012016) NSR Reaction Ep (MeV) Cross Section File X4 Dataset Date Added 2004TU02 6Li(p, ): coincidence yields, deduced S-factors low 1, S-factors from ...

  3. Poster

    Office of Scientific and Technical Information (OSTI)

    HuMiChip: Development of a Functional Gene Array for the Study of Human Microbiomes Qichao Tu 1 , Ye Deng 1 , Lu Lin 12 , Jian Xu 2 , Chris L. Hemme 1 , Zhili He 1 , Jizhong Zhou 1 ...

  4. SOWFA Super-Controller: A High Fidelity Tool for Evaluating Wind...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and P. Moriarty National Renewable Energy Laboratory P. Gebraad and J. van Wingerden TU Delft To be presented at EWEA 2013 Vienna, Austria February 4-7, 2013 Conference ...

  5. Integrable Rosochatius deformations of the restricted soliton flows

    SciTech Connect (OSTI)

    Zhou Ruguang

    2007-10-15

    A method to construct integrable Rosochatius deformations of the restricted soliton flows in the setup of Lax formulation is presented. The integrable Rosochatius deformations of the restricted soliton flows such as the restricted Ablowitz-Kaup-Newell-Segur flow, the restricted Tu-Meng flow, the restricted Tu flow with Neumann-type constraints, and the restricted modified Korteweg-de Vries flow, together with their Lax representations, are presented. In addition, a Lax representation of the Jacobi-Rosochatius system is obtained.

  6. Plan Your Visit

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Visit Plan your visit to the museum Experience 40 interactive exhibits revealing nuclear defense history and the research in life sciences, material sciences, space, supercomputing, energy and the environment. August 18, 2014 Visitor in an interactive exhibit Contact Us thumbnail of Tu - Sat: 10 - 5 PM Su & Mon: 1 - 5 PM Free Admission Bradbury Science Museum, 1350 Central Avenue Tu - Sat: 10 - 5 PM Su & Mon: 1 - 5 PM Free Admission Open every day except Thanksgiving, Christmas, and New

  7. geologic-sequestration | netl.doe.gov

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Geological Sequestration Training and Research Program in Capture and Transport: Development of the Most Economical Separation Method for CO2 Capture Project No.: DE-FE0001953 NETL has partnered with Tuskegee University (TU) to provide fundamental research and hands-on training and networking opportunities to undergraduate students at TU in the area of CO2 capture and transport with a focus on the development of the most economical separation methods for pre-combustion CO2 capture. The bulk of

  8. DOE HQ Special Needs in an Emergency

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    T he in fo rm at io n m ay be ag gr eg at ed in to li st s, ch ar ts , an d or gr ap hs . In fo rm at io n pr ov id ed ne ed on ly de sc ri be th e ki nd of as si st an ce re qu ...

  9. Fermilab | Newsroom | Press Releases | August 7, 2015: NOvA Images

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Fermilab Med Res | Hi Res A view across the top of the NOvA far detector in Ash River, Minnesota. Electronics that make up part of the data acquisition system are...

  10. Fermilab | Newsroom | Press Releases | March 2013: NOvA Photos

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NOvA collaboration. Med Res | Hi Res The NOvA detector, currently under construction in Ash River, Minn., stands about 50 feet tall and 50 feet wide. The completed detector will...