Sample records for tsca toxic substances

  1. Toxic Substances Control Act (TSCA) Polychlorinated Biphenyl (PCB)/Radioactive Waste Annual Inventory for Calendar Year 2013

    SciTech Connect (OSTI)

    no author on report

    2014-06-01T23:59:59.000Z

    The Toxic Substances Control Act, 40 CFR 761.65(a)(1) provides an exemption from the one year storage time limit for PCB/radioactive waste. PCB/radioactive waste may exceed the one year time limit provided that the provisions at 40 CFR 761.65(a)(2)(ii) and 40 CFR 761.65(a)(2)(iii) are followed. These two subsections require, (ii) "A written record documenting all continuing attempts to secure disposal is maintained until the waste is disposed of" and (iii) "The written record required by subsection (ii) of this section is available for inspection or submission if requested by EPA." EPA Region 10 has requested the Department of Energy (DOE) to submit an inventory of radioactive-contaminated PCB waste in storage at the Idaho National Laboratory (INL) for the previous calendar year. The annual inventory is separated into two parts, INL without Advanced Mixed Waste Treatment Project (AMWTP) (this includes Battelle Energy Alliance, LLC, CH2M-WG Idaho, LLC, and the Naval Reactors Facility), and AMWTP.

  2. Toxic Substances Control Act Uranium Enrichment Federal Facility...

    Office of Environmental Management (EM)

    Toxic Substances Control Act Uranium Enrichment Federal Facility Compliance Agreement Toxic Substances Control Act Uranium Enrichment Federal Facility Compliance Agreement Toxic...

  3. Toxicities of selected substances to freshwater biota

    SciTech Connect (OSTI)

    Hohreiter, D.W.

    1980-05-01T23:59:59.000Z

    The amount of data available concerning the toxicity of various substances to freshwater biota is so large that it is difficult to use in a practical situation, such as environmental impact assessment. In this document, summary tables are presented showing acute and/or chronic toxicity of selected substances for various groups of aquatic biota. Each entry is referenced to its original source so that details concerning experimental conditions may be consulted. In addition, general information concerning factors modifying toxicity, synergisms, evidence of bioaccumulation, and water quality standards and criteria for the selected substances is given. The final table is a general toxicity table designed to provide an easily accessible and general indication of toxicity of selected substances in aquatic systems.

  4. Uranium effluent testing for the Oak Ridge Toxic Substances Control Act mixed waste incinerator

    SciTech Connect (OSTI)

    Shor, J.T. [Oak Ridge National Lab., TN (United States); Bostick, W.D.; Hoffmann, D.P.; Gibson, L.V. Jr. [Oak Ridge K-25 Site, TN (United States); Ho, T.C. [Lamar Univ., Beaumont, TX (United States). Dept. of Chemical Engineering

    1993-07-01T23:59:59.000Z

    The Oak Ridge K-25 Site Toxic Substances Control Act (TSCA) Incinerator has been undergoing a series of routine tests to determine uranium partitioning to the stack, scrubber waters, and bottom ash. This paper discusses the results of the most recent experiment in which relatively high rates of uranium stack gas emissions were identified: 6.11 g/h or 8 wt % based on the uranium feed. These data are compared with earlier data, and an empirical correlation is suggested between the stack emissions of uranium and the product of the uranium and chlorine concentration of the feed. This is consistent with certain findings with other metals, in which increasing chlorine feed contents led to increasing emissions.

  5. TOXIC SUBSTANCES FROM COAL COMBUSTION

    SciTech Connect (OSTI)

    Kolker, A.; Sarofim, A.F.; Palmer, C.A.; Huggins, F.E.; Huffman, G.P.; Lighty, J.; Veranth, J.; Helble, J.J.; Wendt, J.O.L.; Ames, M.R.; Finkelman, R.; Mamani-Paco, M.; Sterling, R.; Mroczkowsky, S.J.; Panagiotou, T.; Seames, W.

    1999-05-10T23:59:59.000Z

    The Clean Air Act Amendments of 1990 identify a number of hazardous air pollutants (HAPs) as candidates for regulation. Should regulations be imposed on HAP emissions from coal-fired power plants, a sound understanding of the fundamental principles controlling the formation and partitioning of toxic species during coal combustion will be needed. With support from the Federal Energy Technology Center (FETC), the Electric Power Research Institute, and VTT (Finland), Physical Sciences Inc. (PSI) has teamed with researchers from USGS, MIT, the University of Arizona (UA), the University of Kentucky (UK), the University of Connecticut (UC), the University of Utah (UU) and the University of North Dakota Energy and Environ-mental Research Center (EERC) to develop a broadly applicable emissions model useful to regulators and utility planners. The new Toxics Partitioning Engineering Model (ToPEM) will be applicable to all combustion conditions including new fuels and coal blends, low-NOx combustion systems, and new power generation plants. Development of ToPEM will be based on PSI's existing Engineering Model for Ash Formation (EMAF). This report covers the reporting period from 1 January 1999 to 31 March 1999. During this period, a full Program Review Meeting was held at the University of Arizona. At this meeting, the progress of each group was reviewed, plans for the following 9 month period were discussed, and action items (principally associated with the transfer of samples and reports among the various investigators) were identified.

  6. TOXIC SUBSTANCES FROM COAL COMBUSTION

    SciTech Connect (OSTI)

    A KOLKER; AF SAROFIM; CL SENIOR; FE HUGGINS; GP HUFFMAN; I OLMEZ; J LIGHTY; JOL WENDT; JOSEPH J HELBLE; MR AMES; N YAP; R FINKELMAN; T PANAGIOTOU; W SEAMES

    1998-12-08T23:59:59.000Z

    The Clean Air Act Amendments of 1990 identify a number of hazardous air pollutants (HAPs) as candidates for regulation. Should regulations be imposed on HAP emissions from coal-fired power plants, a sound understanding of the fundamental principles controlling the formation and partitioning of toxic species during coal combustion will be needed. With support from the Federal Energy Technology Center (FETC), the Electric Power Research Institute, the Lignite Research Council, and VTT (Finland), Physical Sciences Inc. (PSI) has teamed with researchers from USGS, MIT, the University of Arizona (UA), the University of Kentucky (UK), the University of Connecticut (UC), the University of Utah (UU) and the University of North Dakota Energy and Environmental Research Center (EERC) to develop a broadly applicable emissions model useful to regulators and utility planners. The new Toxics Partitioning Engineering Model (ToPEM) will be applicable to all combustion conditions including new fuels and coal blends, low-NO combustion systems, and new power generation x plants. Development of ToPEM will be based on PSI's existing Engineering Model for Ash Formation (EMAF). This report covers the reporting period from 1 July 1998 through 30 September 1998. During this period distribution of all three Phase II coals was completed. Standard analyses for the whole coal samples were also completed. Mössbauer analysis of all project coals and fractions received to date has been completed in order to obtain details of the iron mineralogy. The analyses of arsenic XAFS data for two of the project coals and for some high arsenic coals have been completed. Duplicate splits of the Ohio 5,6,7 and North Dakota lignite samples were taken through all four steps of the selective leaching procedure. Leaching analysis of the Wyodak coal has recently commenced. Preparation of polished coal/epoxy pellets for probe/SEM studies is underway. Some exploratory mercury LIII XAFS work was carried out during August at the Advanced Photon Source (APS), the new synchrotron facility at Argonne National Laboratory, Chicago, IL. Further analysis of small-scale combustion experiments conducted at PSI in Phase I was completed this quarter. The results of these experiments for the first time suggest almost complete vaporization of certain trace elements (Se, Zn) from coal combustion in the flame zone, in accordance with theoretical equilibrium predictions. Other elements (As, Sb, Cr) appeared considerably less volatile and may react with constituents in the bulk ash at combustion temperatures. The combustion section of the University of Arizona's Downflow Combustor was completely rebuilt. The University of Utah worked on setting up EPA Method 26A to give the capability to measure chlorine in flue gas. The chlorine kinetic calculations performed as part of the Phase I program were found to have an error in the initial conditions. Therefore, the calculations were re-done this quarter with the correct starting conditions. Development of a quasi-empirical emissions model based on reported emissions of particulate matter from field measurements was continued this quarter. As a first step in developing the ToPEM, we developed a sub-model that calculates the evaporation of major elements (Na, K, Fe, Si, Al, Ca and Mg) from both inherent and extraneous minerals of coal. During this quarter, this sub-model was included into EMAF, which formed the ToPEM. Experimental data from the Phase I program were used to test and modify the sub-model and the ToPEM.

  7. Glossary of CERCLA, RCRA and TSCA related terms and acronyms. Environmental Guidance

    SciTech Connect (OSTI)

    Not Available

    1993-10-01T23:59:59.000Z

    This glossary contains CERCLA, RCRA and TSCA related terms that are most often encountered in the US Department of Energy (DOE) Environmental Restoration and Emergency Preparedness activities. Detailed definitions are included for key terms. The CERCLA definitions included in this glossary are taken from the Comprehensive Environmental Response, Compensation and Liability Act (CERCLA), as amended and related federal rulemakings. The RCRA definitions included in this glossary are taken from the Resource Conservation and Recovery Act (RCRA) and related federal rulemakings. The TSCA definitions included in this glossary are taken from the Toxic Substances and Control Act (TSCA) and related federal rulemakings. Definitions related to TSCA are limited to those sections in the statute and regulations concerning PCBs and asbestos.Other sources for definitions include additional federal rulemakings, assorted guidance documents prepared by the US Environmental Protection Agency (EPA), guidance and informational documents prepared by the US Department of Energy (DOE), and DOE Orders. The source of each term is noted beside the term. Terms presented in this document reflect revised and new definitions published before July 1, 1993.

  8. Studies on Toxic Substances of Locoweeds, Astragalus earlei and Others. 

    E-Print Network [OSTI]

    Wender, S. H. (Simon Harold); Fraps, G. S. (George Stronach)

    1944-01-01T23:59:59.000Z

    G. S. FRAPS and S. H. WENDER Division of Chemistry TEXAS AGRICULTURAL EXPERIMENT STATION A. R. CONNER, Director College Station, Texas BULLETIN NO. 650 JUNE 1944 STUDIES ON TOXIC SUBSTANCES OF LOCOWEEDS, ASTRAGALUS EARLEI AND OTHERS... AGRICULTURAL AND MECHANICAL COLLEGE OF TEXAS GIBB GILCHRIST, President D-19-744-1500 [Blank Page in Original Bulletin] The concentrated toxic preparation of the loco weed contains several closely related toxic substances. The compounds precipi- tated...

  9. Mutation assays involving blood cells that metabolize toxic substances

    DOE Patents [OSTI]

    Crespi, Charles L. (Downers Grove, IL); Thilly, William G. (Winchester, MA)

    1985-01-01T23:59:59.000Z

    A line of human blood cells which have high levels of oxidative activity (such as oxygenase, oxidase, peroxidase, and hydroxylase activity) is disclosed. Such cells grow in suspension culture, and are useful to determine the mutagenicity of xenobiotic substances that are metabolized into toxic or mutagenic substances. Mutation assays using these cells, and other cells with similar characteristics, are also disclosed.

  10. Mutation assays involving blood cells that metabolize toxic substances

    DOE Patents [OSTI]

    Crespi, C.L.; Thilly, W.G.

    1999-08-10T23:59:59.000Z

    The present invention pertains to a line of human blood cells which have high levels of oxidative activity (such as oxygenase, oxidase, peroxidase, and hydroxylase activity). Such cells grow in suspension culture, and are useful to determine the mutagenicity of xenobiotic substances that are metabolized into toxic or mutagenic substances. The invention also includes mutation assays using these cells, and other cells with similar characteristics. 3 figs.

  11. Mutation assays involving blood cells that metabolize toxic substances

    DOE Patents [OSTI]

    Crespi, Charles L. (Marblehead, MA); Thilly, William G. (Winchester, MA)

    1999-01-01T23:59:59.000Z

    The present invention pertains to a line of human blood cells which have high levels of oxidative activity (such as oxygenase, oxidase, peroxidase, and hydroxylase activity). Such cells grow in suspension culture, and are useful to determine the mutagenicity of xenobiotic substances that are metabolized into toxic or mutagenic substances. The invention also includes mutation assays using these cells, and other cells with similar characteristics.

  12. Progress report and technology status development of an EG and G Berthold LB-150 alpha/beta particulate monitor for use on the East Tennessee Technology Park Toxic Substances Control Act Incinerator

    SciTech Connect (OSTI)

    Shor, J.T.; Singh, S.P.N. [Oak Ridge National Lab., TN (United States). Chemical Technology Div.; Gibson, L.V. Jr. [East Tennessee Technology Park, Oak Ridge, TN (United States). ASO Customer Services Div.

    1998-06-01T23:59:59.000Z

    The purpose of this project was to modify and evaluate a commercially available EG and G Berthold LB-150 alpha-beta radionuclide particulate monitor for the high-temperature and moisture-saturation conditions of the East Tennessee Technology Park (formerly K-25 Site) Toxic Substances Control Act (TSCA) Incinerator stack. The monitor was originally outfitted for operation at gas temperatures of 150 F on the defunct Los Alamos National Laboratory (LANL) controlled air incinerator, and the objective was to widen its operating envelope. A laboratory apparatus was constructed that simulated the effects of water-saturated air at the TSCA Incinerator stack-gas temperatures, 183 F. An instrumented set of heat exchangers was constructed to then condition the gas so that the radionuclide monitor could be operated without condensation. Data were collected under the conditions of the elevated temperatures and humidities and are reported herein, and design considerations of the apparatus are provided. The heat exchangers and humidification equipment performed as designed, the Mylar film held, and the instrument suffered no ill effects. However, for reasons as yet undetermined, the sensitivity of the radionuclide detection diminishes as the gas temperature is elevated, whether the gas is humidified or not. The manufacturer has had no experience with (a) the operation of the monitor under these conditions and (b) any commercial market that might exist for an instrument that operates under these conditions. The monitor was not installed into the radiologically contaminated environment of the TSCA Incinerator stack pending resolution of this technical issue.

  13. Review of organic nitrile incineration at the Toxic Substances Control Act Incinerator

    SciTech Connect (OSTI)

    NONE

    1997-10-01T23:59:59.000Z

    Lockheed Martin Energy Systems, Inc. (LMES) operates the East Tennessee Technology Park (ETTP), formerly called the Oak Ridge K-25 Site, where uranium was enriched under contract with the US Department of Energy (DOE). Currently, ETTP missions include environmental management, waste management (WM), and the development of new technologies. As part of its WM mission, ETTP operates the TSCA (Toxic Substances Control Act) Incinerator (TSCAI) for treatment of hazardous waste and polychlorinated biphenyls (PCBs) contaminated with low-level radioactivity. Beginning in the autumn of 1995, employees from diverse ETTP buildings and departments reported experiencing headaches, fatigue, depression, muscle aches, sleeplessness, and muscle tremors. These symptoms were judged by a physician in the ETTP Health Services Department to be consistent with chronic exposures to hydrogen cyanide (HCN). The National Institute for Occupational Safety and Health (NIOSH) was called in to perform a health hazard evaluation to ascertain whether the employees` illnesses were in fact caused by occupational exposure to HCN. The NIOSH evaluation found no patterns for employees` reported symptoms with respect to work location or department. NIOSH also conducted a comprehensive air sampling study, which did not detect airborne cyanides at the ETTP. Employees, however, expressed concerns that the burning of nitrile-bearing wastes at the TSCAI might have produced HCN as a combustion product. Therefore, LMES and DOE established a multidisciplinary team (TSCAI Technical Review Team) to make a more detailed review of the possibility that combustion of nitrile-bearing wastes at the TSCAI might have either released nitriles or created HCN as a product of incomplete combustion (PIC).

  14. Structure activity relationships to assess new chemicals under TSCA

    SciTech Connect (OSTI)

    Auletta, A.E. [Environmental Protection Agency, Washington, DC (United States)

    1990-12-31T23:59:59.000Z

    Under Section 5 of the Toxic Substances Control Act (TSCA), manufacturers must notify the US Environmental Protection Agency (EPA) 90 days before manufacturing, processing, or importing a new chemical substance. This is referred to as a premanufacture notice (PMN). The PMN must contain certain information including chemical identity, production volume, proposed uses, estimates of exposure and release, and any health or environmental test data that are available to the submitter. Because there is no explicit statutory authority that requires testing of new chemicals prior to their entry into the market, most PMNs are submitted with little or no data. As a result, EPA has developed special techniques for hazard assessment of PMN chemicals. These include (1) evaluation of available data on the chemical itself, (2) evaluation of data on analogues of the PMN, or evaluation of data on metabolites or analogues of metabolites of the PMN, (3) use of quantitative structure activity relationships (QSARs), and (4) knowledge and judgement of scientific assessors in the interpretation and integration of the information developed in the course of the assessment. This approach to evaluating potential hazards of new chemicals is used to identify those that are most in need of addition review of further testing. It should not be viewed as a replacement for testing. 4 tabs.

  15. Effluent testing for the Oak Ridge Toxic Substances Control Act mixed waste incinerator emissions tests of January 16 and 18, 1991

    SciTech Connect (OSTI)

    Shor, J.T. (Oak Ridge National Lab., TN (United States)); Bostick, W.D.; Coroneos, A.C.; Bunch, D.H.; Gibson, L.V.; Hoffmann, D.P.; Shoemaker, J.L. (Oak Ridge K-25 Site, TN (United States))

    1992-02-01T23:59:59.000Z

    On January 16 and 18, 1991, special emissions tests were conducted at the Oak Ridge, K-25 Site Toxic Substances Control Act (TSCA) Incinerator. Both tests were approximately 6 h long and were performed at TSCA temperatures (1200{degrees}C, secondary combustion chamber (SSC)). Liquid feed and effluent samples were collected every 30 min. A filter was used to collect particles from stack gases to study morphology and composition during the first test. Isokinetic air samples were also taken during the second test. Metals emissions from the second test were evaluated using the Environmental Protection Agency (EPA) Method 5 sampling train. The aqueous waste was collected and fed in batches to the Central Neutralization Facility (CNF), where it was treated by iron coprecipitation and polymer flocculation and data were collected. In the first test (1-16-91), the aqueous and organic wastes were fed directly to the kiln or primary combustion chamber (PCC). In the second test (1-18-91), the remaining organic waste from the first test was fed into the SSC, and other organic waste was fed into the PCC. One objective of the two tests was to determine if feeding the same organic waste into the two combustion chambers made a difference in a partitioning of uranium and other metals. No evaluation of radionuclides other than uranium was made. The partition coefficient of uranium to the quench water was 0.3 on January 16 and 0.35 on January 18; so directing Tank 306A to the feed to the primary vs the secondary combustion chamber appears to have made little difference. The partition coefficient of uranium to the stack on January 18 was 0.0039. 5 refs., 15 figs., 26 tabs.

  16. Effluent testing for the Oak Ridge Toxic Substances Control Act mixed waste incinerator emissions tests of January 16 and 18, 1991

    SciTech Connect (OSTI)

    Shor, J.T. [Oak Ridge National Lab., TN (United States); Bostick, W.D.; Coroneos, A.C.; Bunch, D.H.; Gibson, L.V.; Hoffmann, D.P.; Shoemaker, J.L. [Oak Ridge K-25 Site, TN (United States)

    1992-02-01T23:59:59.000Z

    On January 16 and 18, 1991, special emissions tests were conducted at the Oak Ridge, K-25 Site Toxic Substances Control Act (TSCA) Incinerator. Both tests were approximately 6 h long and were performed at TSCA temperatures [1200{degrees}C, secondary combustion chamber (SSC)]. Liquid feed and effluent samples were collected every 30 min. A filter was used to collect particles from stack gases to study morphology and composition during the first test. Isokinetic air samples were also taken during the second test. Metals emissions from the second test were evaluated using the Environmental Protection Agency (EPA) Method 5 sampling train. The aqueous waste was collected and fed in batches to the Central Neutralization Facility (CNF), where it was treated by iron coprecipitation and polymer flocculation and data were collected. In the first test (1-16-91), the aqueous and organic wastes were fed directly to the kiln or primary combustion chamber (PCC). In the second test (1-18-91), the remaining organic waste from the first test was fed into the SSC, and other organic waste was fed into the PCC. One objective of the two tests was to determine if feeding the same organic waste into the two combustion chambers made a difference in a partitioning of uranium and other metals. No evaluation of radionuclides other than uranium was made. The partition coefficient of uranium to the quench water was 0.3 on January 16 and 0.35 on January 18; so directing Tank 306A to the feed to the primary vs the secondary combustion chamber appears to have made little difference. The partition coefficient of uranium to the stack on January 18 was 0.0039. 5 refs., 15 figs., 26 tabs.

  17. Toxic substances form coal combustion--a co prehemsice assessment

    SciTech Connect (OSTI)

    Huggins, F.; Huffman, G.P.; Shah, N. [University of Kentucky, Lexington, KY (United States)

    1997-04-01T23:59:59.000Z

    The Clean Coal Act Amendments of 1990 identify a number of hazardous air pollutants as candidates for regulation. Should regulations be imposed on emission of these pollutants from coal-fired power plants, a sound understanding of the fundamental principles controlling their formation and partition will be needed. A new Toxics Partitioning Engineering Model (ToPEM) has been developed by a broad consortium to be useful to regulators and utility planners. During the last quarter coal analysis was completed on the final program coal, from the Wyodak Seam of the Powder River Basin, Combustion testing continued, including data collected on the self-sustained combustor. Efforts were directed to identify the governing mechanisms for trace element vaporization from the program coals. Mercury speciation and measurements were continued. Review of the existing trace element and organics emission literature was completed. And, model development was begun.

  18. TOXIC SUBSTANCES FROM COAL COMBUSTION-A COMPREHENSIVE ASSESSMENT

    SciTech Connect (OSTI)

    C.L. Senior; F. Huggins; G.P. Huffman; N. Shah; N. Yap; J.O.L. Wendt; W. Seames; M.R. Ames; A.F. Sarofim; S. Swenson; J.S. Lighty; A. Kolker; R. Finkelman; C.A. Palmer; S.J. Mroczkowski; J.J. Helble; R. Mamani-Paco; R. Sterling; G. Dunham; S. Miller

    2001-06-30T23:59:59.000Z

    The Clean Air Act Amendments of 1990 identify a number of hazardous air pollutants (HAPs) as candidates for regulation. Should regulations be imposed on HAP emissions from coal-fired power plants, a sound understanding of the fundamental principles controlling the formation and partitioning of toxic species during coal combustion will be needed. With support from the National Energy Technology Laboratory (NETL), the Electric Power Research Institute, and VTT (Finland), Physical Sciences Inc. (PSI) has teamed with researchers from USGS, MIT, the University of Arizona (UA), the University of Kentucky (UK), the University of Connecticut (UC), the University of Utah (UU) and the University of North Dakota Energy and Environmental Research Center (EERC) to develop a broadly applicable emissions model useful to regulators and utility planners. The new Toxics Partitioning Engineering Model (ToPEM) will be applicable to all combustion conditions including new fuels and coal blends, low-NOx combustion systems, and new power generation plants. Development of ToPEM will be based on PSI's existing Engineering Model for Ash Formation (EMAF). The work discussed in this report covers the Phase II program. Five coals were studied (three in Phase I and two new ones in Phase II). In this work UK has used XAFS and Moessbauer spectroscopies to characterize elements in project coals. For coals, the principal use was to supply direct information about certain hazardous and other key elements (iron) to complement the more complete indirect investigation of elemental modes of occurrence being carried out by colleagues at USGS. Iterative selective leaching using ammonium acetate, HCl, HF, and HNO3, used in conjunction with mineral identification/quantification, and microanalysis of individual mineral grains, has allowed USGS to delineate modes of occurrence for 44 elements. The Phase II coals show rank-dependent systematic differences in trace-element modes of occurrence. The work at UU focused on the behavior of trace metals in the combustion zone by studying vaporization from single coal particles. The coals were burned at 1700 K under a series of fuel-rich and oxygen-rich conditions. The data collected in this study will be applied to a model that accounts for the full equilibrium between carbon monoxide and carbon dioxide. The model also considers many other reactions taking place in the combustion zone, and involves the diffusion of gases into the particle and combustion products away from the particle. A comprehensive study has been conducted at UA to investigate the post-combustion partitioning of trace elements during large-scale combustion of pulverized coal combustion. For many coals, there are three distinct particle regions developed by three separate mechanisms: (1) a submicron fume, (2) a micron-sized fragmentation region, and (3) a bulk (>3 {micro}m) fly ash region. The controlling partitioning mechanisms for trace elements may be different in each of the three particle regions. A substantial majority of semi-volatile trace elements (e.g., As, Se, Sb, Cd, Zn, Pb) volatilize during combustion. The most common partitioning mechanism for semi-volatile elements is reaction with active fly ash surface sites. Experiments conducted under this program at UC focused on measuring mercury oxidation under cooling rates representative of the convective section of a coal-fired boiler to determine the extent of homogeneous mercury oxidation under these conditions. In fixed bed studies at EERC, five different test series were planned to evaluate the effects of temperature, mercury concentration, mercury species, stoichiometric ratio of combustion air, and ash source. Ash samples generated at UA and collected from full-scale power plants were evaluated. Extensive work was carried out at UK during this program to develop new methods for identification of mercury species in fly ash and sorbents. We demonstrated the usefulness of XAFS spectroscopy for the speciation of mercury captured on low-temperature sorbents from combustion flue gases and dev

  19. Toxic substances from coal combustion -- A comprehensive assessment

    SciTech Connect (OSTI)

    C.L. Senior; T. Panagiotou; F.E. Huggins; G.P. Huffman; N. Yap; J.O.L. Wendt; W. Seames; M.R. Ames; A.F Sarofim; J. Lighty; A. Kolker; R. Finkelman; C.A. Palmer; S.J. Mroczkowsky; J.J. Helble; R. Mamani-Paco

    1999-11-01T23:59:59.000Z

    The Clean Air Act Amendments of 1990 identify a number of hazardous air pollutants (HAPs) as candidates for regulation. Should regulations be imposed on HAP emissions from coal-fired power plants, a sound understanding of the fundamental principles controlling the formation and partitioning of toxic species during coal combustion will be needed. With support from the Federal Energy Technology Center (FETC), the Electric Power Research Institute, and VTT (Finland), Physical Sciences Inc. (PSI) has teamed with researchers from USGS, MIT, the University of Arizona (UA), the University of Kentucky (UK), the University of Connecticut (UC), the University of Utah (UU) and the University of North Dakota Energy and Environmental Research Center (EERC) to develop a broadly applicable emissions model useful to regulators and utility planners. The new Toxics Partitioning Engineering Model (ToPEM) will be applicable to all combustion conditions including new fuels and coal blends, low-NOx combustion systems, and new power generation plants. Development of ToPEM will be based on PSI's existing Engineering Model for Ash Formation (EMAF). This report covers the reporting period from 1 July 1999 to 30 September 1999. During this period the MIT INAA procedures were revised to improve the quality of the analytical results. Two steps have been taken to reduce the analytical errors. A new nitric acid leaching procedure, modified from ASTM procedure D2492, section 7.3.1 for determination of pyritic sulfur, was developed by USGS and validated. To date, analytical results have been returned for all but the last complete round of the four-step leaching procedure. USGS analysts in Denver have halted development of the cold vapor atomic fluorescence technique for mercury analysis procedure in favor of a new direct analyzer for Hg that the USGS is in the process of acquiring. Since early June, emphasis at USGS has been placed on microanalysis of clay minerals in project coals in preparation for use of the Stanford/USGS SHRIMP RG Ion Microprobe during August 1999. The SHRIMP-RG data confirm that Cr is present at concentrations of about 20 to 120 ppm, just below the electron microprobe detection limits (100 to 200 ppm), as suspected from Phase 1 microprobe work and previous studies of clay mineral separates. The University of Utah has started trial runs on the drop tube furnace to ensure that the gas analysis system is working properly and that the flow pattern within the furnace is laminar and direct. A third set of ASTM samples will be prepared at the University of Utah for the Phase 1 and Phase 2 coals. This time the INAA counting time will be optimized for the elements in which the authors are interested, guided by the results from the first two samples. The iodated charcoal which was used by MIT for vapor phase Hg collection was tested to see whether it collected other vapor phase metals. A second set of tests were performed at PSI using the entrained flow reactor (EFR). The University of Arizona's pilot-scale downflow laboratory combustion furnace was used to test the partitioning of toxic metals in the baseline experiments for the Phase 2 North Dakota lignite and the Pittsburgh seam bituminous coal at baghouse inlet sampling conditions. In addition, baseline data were collected on combustion of the Phase 1 Kentucky Elkhorn/Hazard bituminous coal. Emphasis at the University of Kentucky was placed on (1) collection of new Hg XAFS data for various sorbents, and (2) on collection of XAFS and other data for arsenic, sulfur, chromium and selenium in two baseline ash samples from the University of Arizona combustion unit. A preliminary interpretation of the mercury data is given in this report. Revision was made to the matrix for the initial experiments on mercury-ash interactions to be conducted at EERC. The overall goal of this effort is to collect data which will allow one to model the interactions of mercury and fly ash (specifically, adsorption of Hg{sup 0} and Hg{sup +2} and oxidation of Hg{sup 0}) in the air heater and particulate control dev

  20. Integration of site-specific health information: Agency for Toxic Substances and Disease Registry health assessments

    SciTech Connect (OSTI)

    Lesperance, A.M.; Siegel, M.R.

    1990-12-01T23:59:59.000Z

    The Agency for Toxic Substances and Disease Registry is required to conduct a health assessment of any site that is listed on or proposed for the US Environmental Protection Agency's National Priorities List. Sixteen US Department of Energy (DOE) sites currently fall into this category. Health assessments contain a qualitative description of impacts to public health and the environment from hazardous waste sites, as well as recommendations for actions to mitigate or eliminate risk. Because these recommendations may have major impacts on compliance activities at DOE facilities, the health assessments are an important source of information for the monitoring activities of DOE's Office of Environmental Compliance (OEC). This report provides an overview of the activities involved in preparing the health assessment, its role in environmental management, and its key elements.

  1. Stabilization/solidification of TSCA incinerator ash

    SciTech Connect (OSTI)

    Spence, R.D.; Trotter, D.R.; Francis, C.L.; Morgan, I.L.

    1994-06-01T23:59:59.000Z

    Stabilization/solidification is a well-known waste treatment technique that utilizes different additives and processes. The Phoenix Ash Technology of the Technical Innovation Development Engineering Company is such a technique that uses Cass C fly ash and mechanical pressure to make brick waste forms out of solid wastes, such as the bottom ash from the Toxic Substances Control Act incinerator at the Oak Ridge K-25 Site. One advantage of this technique is that no volume increase over the bulk volume of the bottom ash occurs. This technique should have the same high pH stabilization for Resource Conservation and Recovery Act metals as similar techniques. Also, consolidation of the bottom ash minimizes the potential problems of material dispersion and container corrosion. The bottom ash was spiked with {sup 99}{Tc} to test the effectiveness of the bricks as a physical barrier. The {sup 99}{Tc} leachability index measured for these bricks was 6.8, typical for the pertechnetate anion in cementitious waste forms, indicating that these bricks have accessible porosity as high as that of other cementitious waste forms, despite the mechanical compression, higher waste form density, and water resistant polymer coating.

  2. Toxic Substances Control Act Uranium Enrichment Federal Facilities Compliance Agreement, February 20, 1992 Summary

    Office of Environmental Management (EM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742 33 1112011 Strategic2Uranium Transferon theTed DonatEnergy Electric Thomas L. McCall, Jr.Toxic

  3. California Environmental Protection Agency Department of Toxic...

    Open Energy Info (EERE)

    California Environmental Protection Agency Department of Toxic Substances Control Jump to: navigation, search Name: California Environmental Protection Agency Department of Toxic...

  4. The TSCA interagency testing committee`s approaches to screening and scoring chemicals and chemical groups: 1977-1983

    SciTech Connect (OSTI)

    Walker, J.D. [Environmental Protection Agency, Washington, DC (United States)

    1990-12-31T23:59:59.000Z

    This paper describes the TSCA interagency testing committee`s (ITC) approaches to screening and scoring chemicals and chemical groups between 1977 and 1983. During this time the ITC conducted five scoring exercises to select chemicals and chemical groups for detailed review and to determine which of these chemicals and chemical groups should be added to the TSCA Section 4(e) Priority Testing List. 29 refs., 1 fig., 2 tabs.

  5. Toxic remediation

    DOE Patents [OSTI]

    Matthews, Stephen M. (Alamed County, CA); Schonberg, Russell G. (Santa Clara County, CA); Fadness, David R. (Santa Clara County, CA)

    1994-01-01T23:59:59.000Z

    What is disclosed is a novel toxic waste remediation system designed to provide on-site destruction of a wide variety of hazardous organic volatile hydrocarbons, including but not limited to halogenated and aromatic hydrocarbons in the vapor phase. This invention utilizes a detoxification plenum and radiation treatment which transforms hazardous organic compounds into non-hazardous substances.

  6. K-1435 Wastewater Treatment System for the Toxic Substances Control Act Incinerator Wastewater at the East Tennessee Technology Park, Oak Ridge, TN

    SciTech Connect (OSTI)

    Swientoniewski M.D.

    2008-02-24T23:59:59.000Z

    This paper discusses the design and performance of a wastewater treatment system installed to support the operation of a hazardous waste incinerator. The Oak Ridge Toxic Substances Control Act Incinerator (TSCAI), located at the East Tennessee Technology Park (ETTP), is designed and permitted to treat Resource ConservatioN and Recovery Act (RCRA) wastes including characteristic and listed wastes and polychlorinated biphenyl (PCB)-contaminated mixed waste. the incinerator process generates acidic gases and particulates which consist of salts, metals, and radionuclides. These off-gases from the incinerator are treated with a wet off-gas scrubber system. The recirculated water is continuously purged (below down), resulting in a wastewater to be treated. Additional water sources are also collected on the site for treatment, including storm water that infiltrates into diked areas and fire water from the incinerator's suppression system. To meet regulatory requirements for discharge, a wastewater treatment system (WWTS) was designed, constructed, and operated to treat these water sources. The WWTS was designed to provide for periodic fluctuation of contaminant concentrations due to various feed streams to the incinverator. Blow down consists of total suspended solids (TSS) and total dissolved solids (TDS), encompassing metals, radionuclide contamination and trace organics. The system design flow rate range is 35 to 75 gallons per minute (gpm). The system is designed with redundancy to minimize time off-line and to reduce impacts to the TSCAI operations. A novel treatment system uses several unit operations, including chemical feed systems, two-stage chemical reaction treatment, microfiltration, sludge storage and dewatering, neutralization, granular activated carbon, effluent neutralization, and a complete programmable logic controller (PLC) and human-machine interface (HMI) control system. To meet the space requirements and to provide portability of the WWTS to other applications, the system was installed in three, over-the-road semi trailers, and interconnected with piping and power. Trailers were oriented on a small site footprint to facilitate ease of installation. A remote sump pump skid was provided to convey water from two holding sumps adjacent to the treatment process. An accumulation tank and pump were also provided to receive miscellaneous wastewaters for treatment if they meet the waste acceptance criteria. The paper includes details of the technology used in the design, the requirements for compliance, and the initial performance demonstration and jar testing results. The WWTS successfully allowed for highly efficient, high-volume treatment with compliant discharge to off-site surface water.

  7. Toxic Pollution Prevention Act (Illinois)

    Broader source: Energy.gov [DOE]

    It is the purpose of this Act to reduce the disposal and release of toxic substances which may have adverse and serious health and environmental effects, to promote toxic pollution prevention as...

  8. Toxics Use Reduction Act (Massachusetts)

    Broader source: Energy.gov [DOE]

    This Act, revised significantly in 2006, seeks to mitigate the use of toxic substances and the production of toxic byproducts through reporting requirements as well as resource conservation plans...

  9. Protective mask for airborne toxic substances

    SciTech Connect (OSTI)

    Shoemaker, C.J.; Scavnicky, J.A.; Little, M.E.; Hagy, E.M.; Bloom, A.

    1983-10-21T23:59:59.000Z

    A protective mask is described which includes a one-piece face piece molded of a transparent elastomer. A visor in the face piece provides panoramic visibility and is resilient enough to deform under applied force to permit improved use of optical devices. Identical left and right cheek fittings permit installation of a canister on either side so that the same mask can be used by right-handed and left-handed wearers voice for use with a telephone and the like. Air deflectors inside the mask adjacent the left and right cheek fittings deflect de-foging air along the inside surface of the visor when either left or right or both cheek fittings are used for attachment of a canister. A sealing adapter permits sealing around earpiece shafts of eyeglasses.

  10. Method of removing and detoxifying a phosphorus-based substance

    DOE Patents [OSTI]

    Vandegrift, G.F.; Steindler, M.J.

    1985-05-21T23:59:59.000Z

    A method of removing a phosphorus-based poisonous substance from water contaminated is presented. In addition, the toxicity of the phosphorus-based substance is also subsequently destroyed. A water-immiscible organic solvent is first immobilized on a supported liquid membrane before the contaminated water is contacted with one side of the supported liquid membrane to absorb the phosphorus-based substance in the organic solvent. The other side of the supported liquid membrane is contacted with a hydroxy-affording strong base to react with phosphorus-based solvated species to form a non-toxic product.

  11. Toxic Remediation System And Method

    DOE Patents [OSTI]

    Matthews, Stephen M. (Alameda County, CA); Schonberg, Russell G. (Santa Clara County, CA); Fadness, David R. (Santa Clara County, CA)

    1996-07-23T23:59:59.000Z

    What is disclosed is a novel toxic waste remediation system designed to provide on-site destruction of a wide variety of hazardous organic volatile hydrocarbons, including but not limited to halogenated and aromatic hydrocarbons in the vapor phase. This invention utilizes a detoxification plenum and radiation treatment which transforms hazardous organic compounds into non-hazardous substances.

  12. Hazardous and radioactive substances in

    E-Print Network [OSTI]

    , and a number of other organic substances, as well as some biological effects of hazardous substances. Chapter 3 substances in the marine food web ...12 1.3 Effects of hazardous substances in the marine environment ..........................................40 2.5 Other organic substances............................................

  13. A question of substance

    E-Print Network [OSTI]

    Gitlin, Jane M

    1986-01-01T23:59:59.000Z

    During the week of January 27th to February 2nd, 1986 a design symposium was held in the Department of Architecture at Massachusetts Institute of Technology. This symposium, entitled "An Architecture of Substance" was ...

  14. Studies on Toxic Substances of Locoweeds, Astragalus earlei and Others.

    E-Print Network [OSTI]

    Wender, S. H. (Simon Harold); Fraps, G. S. (George Stronach)

    1944-01-01T23:59:59.000Z

    - acteristic spectrum absorption curve of the loco compounds. Ex- traction with iso-amyl alcohol and purification with flavianic acid removed impurities. Every active fraction showed the same gen- eral type of spectrum absorption curve, though there were... ............................................................................................................... ................................................................................................ Review of literature Preparation of concentrated locoine extract with phosphotungstic acid .... Purification of locoine phosphotungstate with alcohol ............ ... ............. 8 Purification by two precipitations with phosphotungstic acid...

  15. THE TOXIC SUBSTANCES CONTROL ACT: A CHEMIST'S VIEW

    E-Print Network [OSTI]

    Kland, M.J.

    2011-01-01T23:59:59.000Z

    THE WIDESPREAD USE OF PETROCHEMICAL DERIVATIVES IN FOODS JIN A HIGH TECHNOLOGY PETROCHEMICAL - BASED FERTILIZERS~ ENVIHIGH VOLUME INDUSTRIAL PETROCHEMICALS AS CARCIN- OGENS. No

  16. THE TOXIC SUBSTANCES CONTROL ACT: A CHEMIST'S VIEW

    E-Print Network [OSTI]

    Kland, M.J.

    2011-01-01T23:59:59.000Z

    Sec. Sec. Sec. Sec. St'c. Sec. Sec. S('c. Sec. Sec. Spc.Sec. Spc. Sec. Sec. Sec. Sec. Sec. Sec. Sec. SfC. Sec. Sec.

  17. Toxic substances from coal combustion -- A comprehensive assessment

    SciTech Connect (OSTI)

    Senior, C.L.; Huggins, F.E.; Huffman, G.P.; Shan, N.; Yap, N.; Wendt, J.O.L.; Seames, W.; Ames, M.R.; Sarofim, A.F.; Swenson, S.; Lighty, J.; Kolker, A.; Finkelman, R.; Palmer, C.; Mroczkowski, S.; Helble, J.; Mamani-Paco, R.; Sterling, R.; Dunham, G.; Miller, S.

    2000-08-17T23:59:59.000Z

    The final program review meeting of Phase II was held on June 22 in Salt Lake City. The goals of the meeting were to present work in progress and to identify the remaining critical experiments or analyses, particularly those involving collaboration among various groups. The information presented at the meeting is summarized in this report. Remaining fixed bed, bench-scale experiments at EERC were discussed. There are more ash samples which can be run. Of particular interest are high carbon ash samples to be generated by the University of Arizona this summer and some ash-derived sorbents that EERC has evaluated on a different program. The use of separation techniques (electrostatic or magnetic) was also discussed as a way to understand the active components in the ash with respect to mercury. XAFS analysis of leached and unleached ash samples from the University of Arizona was given a high priority. In order to better understand the fixed bed test results, CCSEM and Moessbauer analyses of those ash samples need to be completed. Utah plans to analyze the ash from the single particle combustion experiments for those major elements not measured by INAA. USGS must still complete mercury analyses on the whole coals and leaching residues. Priorities for further work at the SHRIMP-RG facility include arsenic on ash surfaces and mercury in sulfide minerals. Moessbauer analyses of coal samples from the University of Utah were completed; samples from the top and bottom layers of containers of five different coals showed little oxidation of pyrite in the top relative to the bottom except for Wyodak.

  18. California Environmental Protection Agency Department of Toxic Substances

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directedAnnualProperty EditCalifornia:Power LP Biomass Facilityin Charts Jump28TransportationDivisionControl

  19. Toxic Substances Control Act Uranium Enrichment Federal Facility Compliance

    Energy Savers [EERE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directedAnnual Siteof Energy 2, 2015 - JanuaryTankToledo, Ohio, Data DashboardTools forConstruction

  20. Toxic Substances Control Act Uranium Enrichment Federal Facility Compliance

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOn April 23,EnergyChicopeeTechnologyfact sheet summarizesof Energy TheForAgreement |

  1. PCB annual report for Oak Ridge National Laboratory EPA Identification Number - TN 1890090003, February 6, 1990--December 31, 1990

    SciTech Connect (OSTI)

    Greer, J.K. Jr.; Foley, R.C.

    1991-10-15T23:59:59.000Z

    Oak Ridge National Laboratory prepares a report annually as mandated by the Toxic Substances Control Act (TSCA) that summarizes records required of owners/operators of facilities where PCBs are in use. This report provides information of PCB and PCB-contaminated equipment in use or removed from service and PCB wastes generated, stored, and shipped off-site for treatment and disposal during the time period February 6, 1990, through December 31, 1990, as required by the revised TSCA regulations described in the December 21, 1989, Federal Register (54 FR 52716).

  2. Hazardous Substances Act (South Carolina)

    Broader source: Energy.gov [DOE]

    The Commissioner of the Department of Agriculture has the authority to promulgate regulations declaring specified substances to be hazardous and establishing labeling, transportation, storage, and...

  3. RECORD OF DESIGNATED SUBSTANCE ASSESSMENT SUBSTANCE: LEAD (plates and Gamma

    E-Print Network [OSTI]

    Thompson, Michael

    RECORD OF DESIGNATED SUBSTANCE ASSESSMENT SUBSTANCE: LEAD (plates and Gamma Source holder) DATE Direct / Indirect Per Month / Year Lead Mechanical Indirect No change Engineering CONCLUSIONS Read the plant? Product Title: Lead Type of Container: none Size of Container: not applicable 2. Is this form

  4. Federal Substance Abuse Testing Program

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2014-01-30T23:59:59.000Z

    The Order establishes the requirements and responsibilities for the DOE Federal Substance Abuse Testing Program which covers drug and alcohol testing. Cancels DOE O 3792.3 Chg 1.

  5. Field Evaluation of MERCEM Mercury Emission Analyzer System at the Oak Ridge TSCA Incinerator East Tennessee Technology Park Oak Ridge, Tennessee

    SciTech Connect (OSTI)

    None

    2000-03-01T23:59:59.000Z

    The authors reached the following conclusions: (1) The two-month evaluation of the MERCEM total mercury monitor from Perkin Elmer provided a useful venue in determining the feasibility of using a CEM to measure total mercury in a saturated flue gas. (2) The MERCEM exhibited potential at a mixed waste incinerator to meet requirements proposed in PS12 under conditions of operation with liquid feeds only at stack mercury concentrations in the range of proposed MACT standards. (3) Performance of the MERCEM under conditions of incinerating solid and liquid wastes simultaneously was less reliable than while feeding liquid feeds only for the operating conditions and configuration of the host facility. (4) The permeation tube calibration method used in this test relied on the CEM internal volumetric and time constants to relate back to a concentration, whereas a compressed gas cylinder concentration is totally independent of the analyzer mass flowmeter and flowrates. (5) Mercury concentration in the compressed gas cylinders was fairly stable over a 5-month period. (6) The reliability of available reference materials was not fully demonstrated without further evaluation of their incorporation into routine operating procedures performed by facility personnel. (7) The degree of mercury control occurring in the TSCA Incinerator off-gas cleaning system could not be quantified from the data collected in this study. (8) It was possible to conduct the demonstration at a facility incinerating radioactively contaminated wastes and to release the equipment for later unrestricted use elsewhere. (9) Experience gained by this testing answered additional site-specific and general questions regarding the operation and maintenance of CEMs and their use in compliance monitoring of total mercury emissions from hazardous waste incinerators.

  6. Coordination of Care in Substance Abuse Treatment: An Interorganizational Perspective

    E-Print Network [OSTI]

    Spear, Suzanne Evelyn

    2012-01-01T23:59:59.000Z

    substance abuse treatment under the Affordable Care Act.Coordination of Care in Substance Abuse Treatment: AnCoordination of Care in Substance Abuse Treatment: An

  7. antifungi substances produced: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    extract was diluted with physiologic saline solution to a volume corresponding L. Bennett; B. Beeson 1953-01-01 3 Substance Use Disorders (Substance Dependence and Substance...

  8. antiphagocytic substances produced: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    extract was diluted with physiologic saline solution to a volume corresponding L. Bennett; B. Beeson 1953-01-01 3 Substance Use Disorders (Substance Dependence and Substance...

  9. The radioactive Substances (Uranium and Thorium) Exemption Order 1962 

    E-Print Network [OSTI]

    Joseph, Keith

    1962-01-01T23:59:59.000Z

    STATUTORY INSTRUMENTS 1962 No.2710 ATOMIC ENERGY AND RADIOACTIVE SUBSTANCES The Radioactive Substances (Uranium and Thorium) Exemption Order 1962...

  10. Extremely Hazardous Substances Risk Management Act (Delaware)

    Broader source: Energy.gov [DOE]

    This act lays out provisions for local governments to implement regulations and standards for the management of extremely hazardous substances, which are defined and categorized as follows:

  11. SNRB{trademark} air toxics monitoring. Final report

    SciTech Connect (OSTI)

    Not Available

    1994-01-01T23:59:59.000Z

    Babcock & Wilcox (B&W) is currently conducting a project under the DOE`s Clean Coal Technology (CCT II) Program to demonstrate its SO{sub x}NO{sub x}-Rox Box{trademark} (SNRB{trademark}) process in a 5 MWe Field Demonstration Unit at Ohio Edison`s R. E. Burger Plant near Shadyside, Ohio. The objective of the SNRB{trademark} Air Toxics Monitoring Project was to provide data on SNRB{trademark} air toxics emissions control performance to B&W and to add to the DOE/EPRI/EPA data base by quantifying the flow rates of selected hazardous substances (or air toxics) in all of the major input and output streams of the SNRB{trademark} process as well as the power plant. Work under the project included the collection and analysis of representative samples of all major input and output streams of the SNRB{trademark} demonstration unit and the power plant, and the subsequent laboratory analysis of these samples to determine the partitioning of the hazardous substances between the various process streams. Material balances for selected air toxics were subsequently calculated around the SNRB{trademark} and host boiler systems, including the removal efficiencies across each of the major air pollution control devices. This report presents results of the SNRB{trademark} Air Toxics Monitoring Project. In addition to the Introduction, a brief description of the test site, including the Boiler No. 8 and the SNRB{trademark} process, is included in Section H. The concentrations of air toxic emissions are presented in Section II according to compound class. Material balances are included in Section IV for three major systems: boiler, electrostatic precipitator, and SNRB{trademark}. Emission factors and removal efficiencies are also presented according to compound class in Sections V and VI, respectively. A data evaluation is provided in Section VII.

  12. p ro g r a m m e The aim of the Non-Toxic Environment Programme is to give an overall picture of Sweden's

    E-Print Network [OSTI]

    p ro g r a m m e The aim of the Non-Toxic Environment Programme is to give an overall picture achievement of the Non-Toxic Environment environmental objective, and for action taken to ensure and the environment will require thorough knowledge of the turnover of these substances in the en- vironment

  13. PROFILING SUBSTANCE ABUSE PROVIDER TRENDS IN

    E-Print Network [OSTI]

    West, Mike

    PROFILING SUBSTANCE ABUSE PROVIDER TRENDS IN HEALTH CARE DELIVERY SYSTEMS || James F. Burgess, Jr using several covariates. This is illustrated here in the context of sub- stance abuse care. One common process monitor for systems delivering substance abuse care is follow-up outpatient care within a certain

  14. CHEMISTRY AND TOXICITY OF

    E-Print Network [OSTI]

    sewer water produced no acute toxicity, and only slightly inhibited Ceriodaphnia reproduction, again) primary treated domestic sewage from greater Vancouver (Annacis Island Wastewater Treatment Plant); (2 exceeded 10 mg/L. Storm sewer water was relatively low in dissolved salts, but contained significant

  15. Extracellular Polymeric Substances from Shewanella sp. HRCR-1...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Polymeric Substances from Shewanella sp. HRCR-1 Biofilms: Characterization by Infrared Spectroscopy and Proteomics Extracellular Polymeric Substances from Shewanella sp. HRCR-1...

  16. The radioactive Substances (Prepared Uranium Thorium Compounds) Exemption Order 1962 

    E-Print Network [OSTI]

    Joseph, Keith

    1962-01-01T23:59:59.000Z

    STATUTORY INSTRUMENTS 1962 No. 2711 ATOMIC ENERGY AND RADIOACI1VE SUBSTANCES The Radioactive Substances (prepared Uranium and Thorium Compounds) Exemption Order 1962...

  17. Humic substance formation during wastewater infiltration

    SciTech Connect (OSTI)

    Siegrist, R.L. (Oak Ridge National Lab., TN (United States)); Hildmann-Smed, R.; Filip, Z.K. (Bundesgesundheitsamt (BGA), Langen (Germany). Inst. fuer Wasser-, Boden- und Lufthygiene); Jenssen, P.D. (Norges Landbrukshoegskole, Aas (Norway). Centre for Soil and Environmental Research)

    1991-01-01T23:59:59.000Z

    Soil infiltration of wastewater effluents is a widely practiced method of treatment and disposal/reuse throughout the world. Renovation of the wastewater results from a wide variety of complex physicochemical and biological processes. One set of processes is speculated to involve the accumulation of organic matter by filtration and sorption followed by formation of humic substances. This humic substance formation can effect the performance of soil treatment systems by contributing to soil pore clogging and reduction in hydraulic capacity, and by yielding reactive substances and an enhancement of purification processes. While there has been a wealth of research into the nature and genesis of humic substances in terrestrial environments, there has been limited research of humic substance formation during soil infiltration of wastewater. The purpose of the research reported herein was to determine if humic substances can form under conditions typical of those present during wastewater infiltration into natural soil systems. This work was conducted during 1989 to 1990 as a collaborative effort between the Centre for Soil and Environmental Research, located in Aas, Norway and the Institute for Water, Soil and Air Hygiene located in Langen, West Germany. 11 refs., 3 figs., 6 tabs.

  18. Hazard Communication Definitions Chemical means any substance or mixture of substances

    E-Print Network [OSTI]

    Slatton, Clint

    Hazard Communication Definitions Chemical means any substance or mixture of substances Container that contains a hazardous chemical. Exposure or exposed means that an employee is subjected in the course of employment to a chemical that is a physical or health hazard and includes potential (e.g. accidental

  19. Guidance on the management of polychlorinated biphenyls (PCBs)

    SciTech Connect (OSTI)

    Not Available

    1993-11-01T23:59:59.000Z

    Polychlorinated biphenyls (PCBs) are a class of synthetic organic chemicals including 209 known isomers, each with from 1 to 10 chlorine atoms on a biphenyl ring. PCBs have a number of desirable properties for industrial applications including thermal stability, flame retardance, and low vapor pressure. Because of these properties, PCBs were widely used as dielectric fluid in electrical equipment such as utility transformers and capacitors. PCBs were also extensively used in hydraulic fluid and heat transfer fluid, in gaskets, as additives in cutting oils and lubricant, and in a variety of other uses. The Toxic Substances Control Act (TSCA) banned the manufacture of PCBs after 1978 in response to emerging information about the adverse health effects of PCBs and their persistence in the environment. In addition, TSCA directed the Administrator of the Environmental Protection Agency (EPA) to prescribe methods for disposal of PCBS, require marking of PCBs with warning labels, and control their use. The TSCA regulations allow continued use of PCBs provided that the use is totally enclosed and does not pose a risk to human health or the environment. However, at the end of their useful life, all PCB materials must be disposed of according to the TSCA regulations. This guidance document uses graphics and flow charts where possible to present the TSCA regulations according to management activities such as use, storage, disposal, and spill cleanup. The document is designed to be read on an as-needed basis; that is, each chapter can stand alone or may be read in combination with others to help the reader determine the regulations relevant to his or her individual situation and needs. Every attempt has been made to include the requirements of other statutes and regulations that apply to PCB materials and provide references for the reader to consult for additional information.

  20. Essential versus potentially toxic dietary substances: A seasonal comparison of essential fatty acids and methyl mercury

    E-Print Network [OSTI]

    Mazumder, Asit

    , Asit Mazumder a a Water and Aquatic Sciences Research Program, University of Victoria, Department of Biology, P.O. Box 3020, Stn. CSC, Victoria, BC V8W 3N5, Canada b Aquatic Ecosystem Management Research, Burlington, ON L7R 4A6, Canada Received 21 August 2007; received in revised form 15 November 2007; accepted

  1. National Center for Environmental Health Agency for Toxic Substances and Disease Registry

    E-Print Network [OSTI]

    to implement community- based interventions, build local coalitions, and track the impact of the disease://www.cdc.gov/asthma/stateprofiles/ Asthma_in_NYS.pdf CS247509-N #12;2 Reducing children's lead exposure is perhaps the greatest

  2. National Center for Environmental Health Agency for Toxic Substances and Disease Registry

    E-Print Network [OSTI]

    in the environment, such as in swamps. Paper mills, the textile industry, petroleum and natural gas extraction of drywall produced in China. State and local health authorities also received similar reports. At this time. Label: Can you see the back side of your drywall? Some drywall from China is stamped with"Made in China

  3. JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH Part A--Toxic/Hazardous Substances & Environmental Engineering

    E-Print Network [OSTI]

    Rockne, Karl J.

    for the remediation of the residual chloroethene. We hypothesized that ethyl lactate, a ``green'' solvent, could serve

  4. National Center for Environmental Health Agency for Toxic Substances and Disease Registry

    E-Print Network [OSTI]

    capacity to help identify children with dangerous exposure to lead. · Connect these families and children's National Center for Environmental Health: Maryland CDC 24/7: Saving Lives. Protecting People from Health Threats. Saving Money through Prevention. Environmental Health Your environment is everything around you

  5. National Center for Environmental Health Agency for Toxic Substances and Disease Registry

    E-Print Network [OSTI]

    , and technical capacity to help identify children with dangerous exposure to lead. · Connect families's National Center for Environmental Health: California CDC 24/7: Saving Lives. Protecting People from Health Threats. Saving Money through Prevention. Environmental Health Your environment is everything around you

  6. National Center for Environmental Health Agency for Toxic Substances and Disease Registry

    E-Print Network [OSTI]

    to lead. · Connect these families and children to appropriate healthcare and case management. · Inspect's National Center for Environmental Health: Montana CDC 24/7: Saving Lives. Protecting People from Health Threats. Saving Money through Prevention. Environmental Health Your environment is everything around you

  7. National Center for Environmental Health Agency for Toxic Substances and Disease Registry

    E-Print Network [OSTI]

    with dangerous exposures to lead. · Connect these families and children to appropriate healthcare and case's National Center for Environmental Health: Illinois CDC 24/7: Saving Lives. Protecting People from Health Threats. Saving Money through Prevention. Environmental Health Your environment is everything around you

  8. National Center for Environmental Health Agency for Toxic Substances and Disease Registry

    E-Print Network [OSTI]

    capacity to help identify children with dangerous exposures to lead. · Connect these families and children's National Center for Environmental Health: Louisiana CDC 24/7: Saving Lives. Protecting People from Health Threats. Saving Money through Prevention. Environmental Health Your environment is everything around you

  9. National Center for Environmental Health Agency for Toxic Substances and Disease Registry

    E-Print Network [OSTI]

    capacity to help identify children with dangerous exposure to lead. · Connect these families and children's National Center for Environmental Health: Connecticut CDC 24/7: Saving Lives. Protecting People from Health Threats. Saving Money through Prevention. Environmental Health Your environment is everything around you

  10. Uncertainty in synthetic biology for release and possibilities for regulation under the Toxic Substances Control Act

    E-Print Network [OSTI]

    Lightfoot, Shlomiya

    2014-01-01T23:59:59.000Z

    The emerging field of synthetic biology is developing rapidly and promises diverse applications. Many anticipated applications, particularly those involving release of engineered microbes into the environment or human ...

  11. Toxic Substances Control Act Uranium Enrichment Federal Facilities Compliance Agreement, February 20, 1992

    Office of Environmental Management (EM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742 33 1112011 Strategic2Uranium Transferon theTed DonatEnergy Electric Thomas L. McCall, Jr.

  12. Toxic Substances Control Act Uranium Enrichment Federal Facilities Compliance Agreement, February 20, 1992

    Office of Environmental Management (EM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742 33 1112011 Strategic2Uranium Transferon theTed DonatEnergy Electric Thomas L. McCall, Jr. Thomas

  13. Toxic Substances Control Act Uranium Enrichment Federal Facilities Compliance Agreement, February 20, 1992 Summary

    Office of Environmental Management (EM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742 33 1112011 Strategic2Uranium Transferon theTed DonatEnergy Electric Thomas L. McCall, Jr.

  14. Detection of toxic factors after gamma-irradiation in vitro and in vivo

    E-Print Network [OSTI]

    Shihabi, Zakariya Kamel

    1965-01-01T23:59:59.000Z

    'scorned Tke mox'taixty of the chlpJf's vas used 88 a cx'lte. '. icn foe tne presence of toxic substances produced by irradiation. 20 Ch ek s er atosoa. The same procedure vas used for the collection and ths bioassay with chicken spermatosea as described t...DETECTION QF TOXIC FACTORS AFTER GAMMA-IRRADIATION ~ V~IO AND IN VIVO A Thesis By Zaksriya K. Shihabi Submitted to the Graduate College of the Texas A & M University in partial fulfillment of the requirements for the degree of MASTER...

  15. Evaluation of metabolic responses of Artemia salina to oil and oil dispersant as a potential indicator of toxicant stress

    SciTech Connect (OSTI)

    Verriopoulos, G.; Moraitou-Apostolopoulou, M.; Xatzispirou, A.

    1986-03-01T23:59:59.000Z

    Oil represents an obvious hazard for the coastal environment and studies on its impact on marine organisms are necessary. Solvent based oil dispersants constitute one of the most important means for removing oil from shores. Although recently new dispersants have been developed, which are much less toxic than the first ones, dispersants still remain toxic substances. Since in the case of oil pollution treatment, oils and detergents are acting in combination, a realistic approach of laboratory studies must also include the combined action of these substances on marine organisms. Although acute toxicity studies are very useful for the determination of the range of animal tolerance, other effects causing physiological alterations may be detrimental to a population's survival. This paper concerns research on the effects of an oil, an oil dispersant and of the mixture of oil and dispersant on a physiological process, the respiration of the brine shrimp Artemia salina.

  16. Quick, portable toxicity testing of marine or terrigenous fluids, sediments, or chemicals with bioluminescent organism

    SciTech Connect (OSTI)

    Sabate, R.W.; Stiffey, A.V.; Dewailly, E.L. [Lumitox Gulf L.C., New Orleans, LA (United States)

    1995-12-31T23:59:59.000Z

    A hand-held, battery-operated instrument, which measures bioluminescence inhibition of the microscopic marine dinoflagellate Pyrocystis lunula, is capable of field-testing substances for toxicity. The organism is sensitive to ppb of strong toxicants. It tolerates some solvents in concentrations necessary for testing lipophylic samples. A test consumes only micrograms of sample. This method requires no adjustments for salinity, pH, color, or turbidity. It has been used successfully to test oil-well drilling fluids, brines produced with oil, waters and sediments from streams and lakes and petroleum-plant effluents containing contaminants such as benzene. The test is non-specific; however, if the substance is known, the end-point effects a direct measurement of its concentration. One-hour toxicity screening tests in the field produce results comparable to the standard four-hour laboratory test. Keeping the sample in the dark during incubation and testing, together with shortness of the overall procedure, eliminates anomalies from light-sensitive substances. Day-to-day variation, as well as among test replicates, is less than 10%. This quick method yields results comparable with a quick test that uses Photobacterium phosphoria, and with 96-hour tests that use Mysidopsis bahia, Artemia salina, Gonyaulax polyedra, Pimephales promelas, Ceriodaphnia dubia, and Cyprinodon variegatus.

  17. Operating cost guidelines for benchmarking DOE thermal treatment systems for low-level mixed waste

    SciTech Connect (OSTI)

    Salmon, R.; Loghry, S.L.; Hermes, W.H.

    1994-11-01T23:59:59.000Z

    This report presents guidelines for estimating operating costs for use in benchmarking US Department of Energy (DOE) low-level mixed waste thermal treatment systems. The guidelines are based on operating cost experience at the DOE Toxic Substances Control Act (TSCA) mixed waste incinerator at the K-25 Site at Oak Ridge. In presenting these guidelines, it should be made clear at the outset that it is not the intention of this report to present operating cost estimates for new technologies, but only guidelines for estimating such costs.

  18. RCRA/UST, superfund, and EPCRA hotline training module. Introduction to: Other laws that interface with RCRA, updated as of July 1995

    SciTech Connect (OSTI)

    NONE

    1995-11-01T23:59:59.000Z

    The module provides a brief overview of some of the major environmental laws that interface with RCRA: Clean Air Act (CAA); Clean Water Act (CWA); Safe Drinking Water Act (SDWA); Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA); Toxic Substances Control Act (TSCA); Pollution Prevention Act (PPA); and Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA or Superfund). It also covers regulations administered by other agencies that interface with RCRA, such as health and safety requirements under the Occupational Health and Safety Administration, and the Hazardous Materials Transportation Requirements administered by the Department of Transportation.

  19. RCRA, superfund and EPCRA hotline training module. Introduction to: Other laws that interface with RCRA, updated July 1996

    SciTech Connect (OSTI)

    NONE

    1996-07-01T23:59:59.000Z

    The module provides a brief overview of some of the major environmental laws that interface with RCRA: Clean Air Act (CAA); Clean Water Act (CWA); Safe Drinking Water Act (SDWA); Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA); Toxic Substances Control Act (TSCA); Pollution Prevention Act (PPA); and Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA or Superfund). It also covers regulations administered by other agencies that interface with RCRA, such as health and safety requirements under the occupational health and safety administration, and the hazardous materials transportation requirements administered by the Department of Transportation.

  20. Fluorine Gas Management Guidelines Fluorine is a highly toxic, pale yellow gas about 1.3 times as heavy as air at atmospheric

    E-Print Network [OSTI]

    de Lijser, Peter

    Fluorine Gas Management Guidelines Overview Fluorine is a highly toxic, pale yellow gas about 1.3 times as heavy as air at atmospheric temperature and pressure. Fluorine gas is the most powerful oxidizing agent known, reacting with practically all organic and inorganic substances. Fluorine gas

  1. Title 40 CFR 300 National Oil and Hazardous Substances Pollution...

    Open Energy Info (EERE)

    National Oil and Hazardous Substances Pollution Contingency Plan Jump to: navigation, search OpenEI Reference LibraryAdd to library Legal Document- Federal RegulationFederal...

  2. Prevention, Abatement, and Control of Hazardous Substance Release (Iowa)

    Broader source: Energy.gov [DOE]

    The Department of Natural Resources is authorized to establish rules regarding the prevention and mitigation of hazardous substance release. These sections contain information on the notification...

  3. antimicrobial substances produced: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    care delivery system studies, the US Department of Veterans A11PROFILING SUBSTANCE ABUSE PROVIDER TRENDS IN HEALTH CARE DELIVERY SYSTEMS || James F. Burgess, Jr., Viridiana...

  4. adolescent substance abuse: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    care delivery system studies, the US Department of Veterans A11PROFILING SUBSTANCE ABUSE PROVIDER TRENDS IN HEALTH CARE DELIVERY SYSTEMS || James F. Burgess, Jr., Viridiana...

  5. antibacterial substances active: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    care delivery system studies, the US Department of Veterans A11PROFILING SUBSTANCE ABUSE PROVIDER TRENDS IN HEALTH CARE DELIVERY SYSTEMS || James F. Burgess, Jr., Viridiana...

  6. Experimental plan for the assessment of air toxic emissions from a pilot-scale combustion unit

    SciTech Connect (OSTI)

    Hargis, R.A.; Pennline, H.W. [Dept. of Energy, Pittsburgh, PA (United States). Pittsburgh Energy Technology Center

    1995-12-31T23:59:59.000Z

    The operation of a 500-pound-per-hour pilot-scale combustion unit will be characterized in terms of the formation, distribution, and fate of toxic substances. The coal fired during the air toxics testing will be the same coal batch that had been fired in a full-scale utility boiler during a recent assessment of air toxic emissions. A description of the pilot unit and expected operating conditions during the air toxics testing is provided, along with a summary of the test plan. This test plan is designed to obtain the necessary data on the concentration of trace elements associated with the vapor phase, particulate phase, and particulate size fraction enabling a comparison of these results form the pilot unit and the full-scale utility. Calculation of material balances around the pilot combustion unit, the baghouse, and the overall system as well as baghouse removal efficiencies will be performed. Based on the results of this air toxics characterization effort, an assessment will be made of the value of the pilot unit as a facility for the evaluation of sampling and analytical improvements, development of continuous emissions monitors, and future control systems evaluations.

  7. Control substances and alcohol use and testing

    SciTech Connect (OSTI)

    Przybylski, J.L.

    1994-07-01T23:59:59.000Z

    The Omnibus Transportation Employee Testing Act was signed into law in October of 1991. The Omnibus Transportation Employee Testing Act of 1991 required the United States Department of Transportation (DOT) to enact regulations requiring the testing of employees that perform ``safety sensitive functions`` for illegal controlled substance use and alcohol misuse. The Transportation Management Division, Office of Environmental Restoration and Waste Management (TMD/EM-261), United States Department of Energy (DOE), Training Program Manager is committed to promoting the availability of the necessary information to those affected members of the Department of Energy (DOE) community in an effort to attain the highest possible level of regulatory compliance and to enhance the safety of each individual in the workplace.

  8. Testing for Toxic Algae By Tadd Barrow

    E-Print Network [OSTI]

    Nebraska-Lincoln, University of

    Testing for Toxic Algae By Tadd Barrow UNL Extension Educator, Water Quality Algae is a microscopic plant that occurs in all water. However, only certain conditions bring algae to the surface, making it toxic to animals, especially humans and dogs. Toxic algae often are naturally occurring from high

  9. Ozone-depleting substances and the greenhouse gases HFCs, PFCs

    E-Print Network [OSTI]

    Ozone-depleting substances and the greenhouse gases HFCs, PFCs and SF6 Danish consumption contribution to the debate on environmental policy in Denmark. #12;3 Contents 1 SUMMARY 5 1.1 OZONE OZONE-DEPLETING SUBSTANCES 19 3.1 IMPORTS AND EXPORTS 19 3.1.1 CFCs 19 3.1.2 Tetrachloromethane 19 3

  10. The Use of Remotely Sensed Bioelectric Action Potentials to Evaluate Episodic Toxicity Events and Ambient Toxicity

    E-Print Network [OSTI]

    Waller, W. Tom; Acevedo, Miguel F.; Allen, H. J.; Schwalm, F. U.

    The exposure of an organism to a toxicant is defined by the magnitude, duration, and frequency with which the organism(s) interact with the toxicant(s). Predicting the exposure of organisms to toxicants during episodic events such as those resulting...

  11. The Use of Remotely Sensed Bioelectric Action Potentials to Evaluate Episodic Toxicity Events and Ambient Toxicity 

    E-Print Network [OSTI]

    Waller, W. Tom; Acevedo, Miguel F.; Allen, H. J.; Schwalm, F. U.

    1996-01-01T23:59:59.000Z

    The exposure of an organism to a toxicant is defined by the magnitude, duration, and frequency with which the organism(s) interact with the toxicant(s). Predicting the exposure of organisms to toxicants during episodic events such as those resulting...

  12. Systematic Evaluation of Nanomaterial Toxicity: Utility of Standardize...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Systematic Evaluation of Nanomaterial Toxicity: Utility of Standardized Materials and Rapid Assays. Systematic Evaluation of Nanomaterial Toxicity: Utility of Standardized...

  13. Confidentiality protections versus collaborative care in the treatment of substance use disorders

    E-Print Network [OSTI]

    Manuel, Jennifer K; Newville, Howard; Larios, Sandra E; Sorensen, James L

    2013-01-01T23:59:59.000Z

    substance abuse treatment with primary care. Substance Abuseof care. The field of substance abuse treatment has changedcare setting “whose primary function is the provision of alcohol or drug abuse diagnosis, treatment

  14. The radioactive Substances (Prepared Uranium and Thorium Compounds) Exemption (Scotland)Order 1962 

    E-Print Network [OSTI]

    Noble, Michael

    1962-01-01T23:59:59.000Z

    STATUTORY INSTRUMENTS 1962 No. 2772 (S. 132) ATOMIC ENERGY AND RADIOACTIVE SUBSTANCES The Radioactive Substances (Prepared Uranium and Thorium Compounds) Exemption (Scotland) Order 1962

  15. The radioactive Substances (Uranium and Thorium) Exemption (Scotland)Order 1962 

    E-Print Network [OSTI]

    Noble, Michael

    1962-01-01T23:59:59.000Z

    STATUTORY INSTRUMENTS 1962 No. 2766 (S. 126) ATOMIC ENERGY AND RADIOACTIVE SUBSTANCES The Radioactive Substances (Uranium and Thorium) Exemption (Scotland) Order 1962...

  16. Resource Management Services: Water Regulation, Parts 595-599: Hazardous Substances (New York)

    Broader source: Energy.gov [DOE]

    These regulations aim to prevent the release of hazardous substances into surface water and groundwater resources. They contain guidance for facilities which store and process hazardous substances,...

  17. Acute lethal toxicity of some reference chemicals to freshwater fishes of Scandinavia

    SciTech Connect (OSTI)

    Oikari, A.O.J.

    1987-07-01T23:59:59.000Z

    Relevance of the choice of a test organism intended to be representative for a given environment seems to be under continual debate in aquatic ecotoxicology. For instance, it is commonly argue that acute toxicity tests with rainbow trout, the species most often recommended as a standard cold water teleost, were not representative for Nordic countries because the species is an alien in local faunas. A comparative study with several freshwater species was therefore initiated to clarify the validity of this assumption. As a first approximation, standard LC 50 assays were conducted. The species used were chosen only on the basis of their local availability, i.e, they randomly represented the fish fauna of Nordic inland waters. Furthermore, inter-species variation of toxicity response was compared with certain other, quantitatively more important, intra-species sources of variability affecting the toxicity of chemicals. Use of reference toxicants has been recommended as a means of standardizing bioassays. Compounds, characteristic of effluents from the pulp and paper industry, were selected for the present study. The toxicity of organic acids such a phenols and resin acids, as well as that of pupmill effluents, strongly depends on water pH. Because of the possibility that species differences could exist in this respect, effects of water acidity on toxicity of these types of substances to a randomly selected local species was investigated. Finally, as an example of the biological source of assay variability, the effect of yolk absorption was studied with a subsequent crisis period due to moderate starvation under laboratory conditions.

  18. antisocial behavior substance: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    scott r. robinson Biology and Medicine Websites Summary: an impact on postnatal behavior. A teratogen is any substance that can be transmitted to the fetus in utero to alter...

  19. Toxic hazards of underground excavation

    SciTech Connect (OSTI)

    Smith, R.; Chitnis, V.; Damasian, M.; Lemm, M.; Popplesdorf, N.; Ryan, T.; Saban, C.; Cohen, J.; Smith, C.; Ciminesi, F.

    1982-09-01T23:59:59.000Z

    Inadvertent intrusion into natural or man-made toxic or hazardous material deposits as a consequence of activities such as mining, excavation or tunnelling has resulted in numerous deaths and injuries in this country. This study is a preliminary investigation to identify and document instances of such fatal or injurious intrusion. An objective is to provide useful insights and information related to potential hazards due to future intrusion into underground radioactive-waste-disposal facilities. The methodology used in this study includes literature review and correspondence with appropriate government agencies and organizations. Key categories of intrusion hazards are asphyxiation, methane, hydrogen sulfide, silica and asbestos, naturally occurring radionuclides, and various mine or waste dump related hazards.

  20. ROYAL HOLLOWAY, UNIVERSITY OF LONDON THE CONTROL OF SUBSTANCES HAZARDOUS TO HEALTH

    E-Print Network [OSTI]

    Sheldon, Nathan D.

    ROYAL HOLLOWAY, UNIVERSITY OF LONDON THE CONTROL OF SUBSTANCES HAZARDOUS TO HEALTH REGULATIONS 2002's arrangements for the management of hazardous substances as defined in the Control of Substances Hazardous who may be affected by the work of the College to substances hazardous to health is either prevented

  1. Chronic Toxicity and Reproduction Studies of

    E-Print Network [OSTI]

    unknown authors

    as an unwanted by-product of certain processes associated with the chlorination of hydrocarbons. Studies were conducted to assess the potential long-term toxicity of HCBD. In a reproduction study conducted in rats, dose levels of 20 or 2.0 mg/kg-day of HCBD induced slight maternal toxicity

  2. Rangeland Risk Management for Texans: Toxic Plants

    E-Print Network [OSTI]

    Hart, Charles R.

    2000-11-01T23:59:59.000Z

    Toxic plants can cause serious losses to livestock, but with the information in this leaflet producers will know how to manage grazing to minimize the danger of toxic plants. It is important to recognize problems early and know how to deal with them....

  3. Rangeland Risk Management for Texans: Toxic Plants 

    E-Print Network [OSTI]

    Hart, Charles R.

    2000-11-01T23:59:59.000Z

    Toxic plants can cause serious losses to livestock, but with the information in this leaflet producers will know how to manage grazing to minimize the danger of toxic plants. It is important to recognize problems early and know how to deal with them....

  4. Enhanced toxic cloud knockdown spray system for decontamination applications

    DOE Patents [OSTI]

    Betty, Rita G. (Rio Rancho, NM); Tucker, Mark D. (Albuquerque, NM); Brockmann, John E. (Albuquerque, NM); Lucero, Daniel A. (Albuquerque, NM); Levin, Bruce L. (Tijeras, NM); Leonard, Jonathan (Albuquerque, NM)

    2011-09-06T23:59:59.000Z

    Methods and systems for knockdown and neutralization of toxic clouds of aerosolized chemical or biological warfare (CBW) agents and toxic industrial chemicals using a non-toxic, non-corrosive aqueous decontamination formulation.

  5. Rangeland Drought Management for Texans: Toxic Range Plants

    E-Print Network [OSTI]

    Hart, Charles R.; Carpenter, Bruce B.

    2001-05-03T23:59:59.000Z

    Toxic plants can pose a major threat to livestock during a drought. This publication explains the importance of knowing which plants are toxic, keeping the range healthy, and preventing toxic plant problems....

  6. Rangeland Drought Management for Texans: Toxic Range Plants 

    E-Print Network [OSTI]

    Hart, Charles R.; Carpenter, Bruce B.

    2001-05-03T23:59:59.000Z

    Toxic plants can pose a major threat to livestock during a drought. This publication explains the importance of knowing which plants are toxic, keeping the range healthy, and preventing toxic plant problems....

  7. acute organ toxicity: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    toxic properties (more) Pessala, Piia 2008-01-01 29 Review The Toxicity of Depleted Uranium CiteSeer Summary: Abstract: Depleted uranium (DU) is an emerging environmental...

  8. A study of toxic emissions from a coal-fired gasification plant. Final report

    SciTech Connect (OSTI)

    NONE

    1995-12-01T23:59:59.000Z

    Under the Fine Particulate Control/Air Toxics Program, the US Department of Energy (DOE) has been performing comprehensive assessments of toxic substance emissions from coal-fired electric utility units. An objective of this program is to provide information to the US Environmental Protection Agency (EPA) for use in evaluating hazardous air pollutant emissions as required by the Clean Air Act Amendments (CAAA) of 1990. The Electric Power Research Institute (EPRI) has also performed comprehensive assessments of emissions from many power plants and provided the information to the EPA. The DOE program was implemented in two. Phase 1 involved the characterization of eight utility units, with options to sample additional units in Phase 2. Radian was one of five contractors selected to perform these toxic emission assessments.Radian`s Phase 1 test site was at southern Company Service`s Plant Yates, Unit 1, which, as part of the DOE`s Clean Coal Technology Program, was demonstrating the CT-121 flue gas desulfurization technology. A commercial-scale prototype integrated gasification-combined cycle (IGCC) power plant was selected by DOE for Phase 2 testing. Funding for the Phase 2 effort was provided by DOE, with assistance from EPRI and the host site, the Louisiana Gasification Technology, Inc. (LGTI) project This document presents the results of that effort.

  9. Staff summary of Issues & Recommendations Toxic Contamination

    E-Print Network [OSTI]

    effects caused by the hydropower system. In particular, investigate whether exposure to toxics and operation of the federal hydropower system: "Fishery resources are clearly affectedby the development and operation of the federal hydropower system. Dam presence can beassociatedwith the accumulation

  10. Differences in growth and toxicity of Karenia

    E-Print Network [OSTI]

    Neely, Tatum Elizabeth

    2006-08-16T23:59:59.000Z

    Harmful algal blooms (HABs) in the Gulf of Mexico are primarily caused by dense aggregations of the dinoflagellate species, Karenia brevis. Karenia brevis produces a highly toxic neurotoxin, brevetoxin which has been shown to cause Neurotoxic...

  11. Differences in growth and toxicity of Karenia 

    E-Print Network [OSTI]

    Neely, Tatum Elizabeth

    2006-08-16T23:59:59.000Z

    Harmful algal blooms (HABs) in the Gulf of Mexico are primarily caused by dense aggregations of the dinoflagellate species, Karenia brevis. Karenia brevis produces a highly toxic neurotoxin, brevetoxin which has been shown to cause Neurotoxic...

  12. Toxicity of trifluoroacetate to aquatic organisms

    SciTech Connect (OSTI)

    Berends, A.G.; Rooij, C.G. de [Solvay S.A., Brussels (Belgium); Boutonnet, J.C. [Elf Atochem, Levallois-Perret (France); Thompson, R.S. [Zeneca Ltd., Devon (United Kingdom). Brixham Environmental Lab.

    1999-05-01T23:59:59.000Z

    As a result of the atmospheric degradation of several hydrofluorocarbons and hydrochlorofluorocarbons, trifluoroacetate (TFA) will be formed. Through precipitation, TFA will enter aquatic ecosystems. To evaluate the impact on the aquatic environment, an aquatic toxicity testing program was carried out with sodium trifluoroacetate (NaTFA). During acute toxicity tests, no effects of NaTFA on water fleas (Daphnia magna) and zebra fish (Danio retrio) were found at a concentration of 1,200 mg/L. A 7-d study with duckweed (Lemna gibba Ge) revealed a NOEC of 300 mg/L. On the basis of the results of five toxicity tests with Selenastrum capricornutum, they determined a NOEC of 0.12 mg/L. However, algal toxicity tests with NaTFA and Chlorella vulgaris, Scenedesmus subspicatus, Chlamydomonas reinhardtii, Dunaliella tertiolecta, Eugelan gracilis, Phaeodactylum tricornutum, Navicula pelliculosa, Skeletonema costatum, Anabaena flos-aquae, and Microcystis aeruginosa resulted in EC50 values that were all higher than 100 mg/L. The toxicity of TFA to S. capricornutum could be due to metabolic defluorination to monofluoroacetate (MFA), which is known to inhibit the citric acid cycle. A toxicity test with MFA and S. capricornutum revealed it to be about three orders of magnitude more toxic than TFA. However, a bioactivation study revealed that defluorination of TFA was less than 4%. On the other hand, S. capricornutum exposed to a toxic concentration of NaTFA showed a recovery of growth when citric acid was added, suggesting that TFA (or a metabolite of TFA) interferes with the citric acid cycle. A recovery of the growth of S. capricornutum was also found when TFA was removed from the test solutions. Therefore, TFA should be considered algistatic and not algicidic for S. capricornutum. On the basis of the combined results of the laboratory tests and a previously reported semi-field study, they can consider a TFA concentration of 0.10 mg/L as safe for the aquatic ecosystem.

  13. Reducing Livestock Losses To Toxic Plants

    E-Print Network [OSTI]

    McGinty, Allan; Machen, Richard V.

    2000-04-25T23:59:59.000Z

    TexasAgriculturalExtensionService The Texas A&M University System Reducing Livestock Losses to Toxic Plants B-1499 Sand Shinnery L Perennial Broomweed Texas Agricultural Extension Service a71 Zerle L. Carpenter, Director a71 The Texas A&M University... ................... ...... ... 6 BehaviorModification.................................. 7 Management Techniques forReducingToxic Plant Losses... 8 LiteratureCited........................................ 9 Poisonous Plants ofTexas...............................10 Editor: Judy Winn...

  14. Toxicity of Bitterweed (Actinea odorata) for Sheep.

    E-Print Network [OSTI]

    Boughton, I. B (Ivan Bertrand); Hardy, W. T. (William Tyree)

    1937-01-01T23:59:59.000Z

    TEXAS AGRICULTURAL EXPERIMENT STATION A. B. CONNER, DIRECTOR COLLEGE STATION, RFCAZOS COUNTY, TEXAS BULLETIN NO. 552 AUGUST, 1937 DIVISION OF VETERINARY SCIENCE TOXICITY OF BI'FTERWEED" FOR SHEEP (*Actinea odorata) AGRICULTURAL... AND MECHANICMIJ COLLEGE OF TEXAS T. 0. WALTON, President Previous feeding tests and field observations* have established the toxicity of bitterweed (Actinea odorata) for sheep. The experi- ments reported herein prove that the minimum lethal dose of the fresh...

  15. Residual Toxicities of Insecticides to Cotton Insects.

    E-Print Network [OSTI]

    Hightower, B. G.; Gaines, J. C.

    1960-01-01T23:59:59.000Z

    Summary Results of experiments conducted to determine leafworm, the salt-marsh caterpillar and the garden the effect of natural or simulated climatic conditions webworm. on the residual toxicities of several chlorinated hydro- carbon... variety of weathering conditions. Based on residual properties alone, toxaphene and dieldrin ranked with endrin and Sevin, but the initial toxicities of dieldrin and endrin to the boll weevil were appreciably greater than those of toxaphene...

  16. Residual Toxicities of Insecticides to Cotton Insects. 

    E-Print Network [OSTI]

    Hightower, B. G.; Gaines, J. C.

    1960-01-01T23:59:59.000Z

    Summary Results of experiments conducted to determine leafworm, the salt-marsh caterpillar and the garden the effect of natural or simulated climatic conditions webworm. on the residual toxicities of several chlorinated hydro- carbon... variety of weathering conditions. Based on residual properties alone, toxaphene and dieldrin ranked with endrin and Sevin, but the initial toxicities of dieldrin and endrin to the boll weevil were appreciably greater than those of toxaphene...

  17. Toxicity of Bitterweed (Actinea odorata) for Sheep. 

    E-Print Network [OSTI]

    Boughton, I. B (Ivan Bertrand); Hardy, W. T. (William Tyree)

    1937-01-01T23:59:59.000Z

    TEXAS AGRICULTURAL EXPERIMENT STATION A. B. CONNER, DIRECTOR COLLEGE STATION, RFCAZOS COUNTY, TEXAS BULLETIN NO. 552 AUGUST, 1937 DIVISION OF VETERINARY SCIENCE TOXICITY OF BI'FTERWEED" FOR SHEEP (*Actinea odorata) AGRICULTURAL... AND MECHANICMIJ COLLEGE OF TEXAS T. 0. WALTON, President Previous feeding tests and field observations* have established the toxicity of bitterweed (Actinea odorata) for sheep. The experi- ments reported herein prove that the minimum lethal dose of the fresh...

  18. Reducing Livestock Losses To Toxic Plants 

    E-Print Network [OSTI]

    McGinty, Allan; Machen, Richard V.

    2000-04-25T23:59:59.000Z

    TexasAgriculturalExtensionService The Texas A&M University System Reducing Livestock Losses to Toxic Plants B-1499 Sand Shinnery L Perennial Broomweed Texas Agricultural Extension Service a71 Zerle L. Carpenter, Director a71 The Texas A&M University... ................... ...... ... 6 BehaviorModification.................................. 7 Management Techniques forReducingToxic Plant Losses... 8 LiteratureCited........................................ 9 Poisonous Plants ofTexas...............................10 Editor: Judy Winn...

  19. Interactions of Arsenic and the Dissolved Substances Derived from

    E-Print Network [OSTI]

    Florida, University of

    As trapping and transport within porous soil media and in developing comprehensive plans for managingInteractions of Arsenic and the Dissolved Substances Derived from Turf Soils Z H A N G R O N G C H University, Miami, Florida 33199, Southeast Environmental Research Center, Florida International University

  20. MAILLER et al. Removal of priority and emerging substances by

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    of micropollutants in conventional wastewater treatment plants (WWTPs) composed by primary and biological treatmentsMAILLER et al. Removal of priority and emerging substances by biological and tertiary treatments in the case of urban areas (Heberer 2002). This implies a large understanding of wastewater treatment

  1. Emissions Trading and Air Toxics Emissions: RECLAIM and Toxics Regulation in the South Coast Air Basin

    E-Print Network [OSTI]

    Cohen, Nancy J.

    1993-01-01T23:59:59.000Z

    Emissions Trading and Air Toxics Emissions: RECLAIM anda mar- ket-based emissions trading program called theimpacts cre- ated by emissions trading programs that affect

  2. Determination of toxic elements in the ecological evaluation of metalliferous deposits of heavy oil and natural bitumens

    SciTech Connect (OSTI)

    Goldberg, I.S.

    1995-12-31T23:59:59.000Z

    Elements such as vanadium, nickel, zinc, arsenic, selenium, and mercury are present in highly toxic compounds in many workable deposits of heavy oil and natural bitumens. Refining this raw material and, especially, using the heavy residues as furnace fuel and as binding material for road paving, can lead to contamination of the environment unless measures are taken to remove the metals. Various investigations of the rare and disseminated elements in heavy oil and natural bitumens have encompassed a broad range of problems: (1) In refining, assessing the role of rare elements in technological processes in order to choose the optimal schemes for refining and improving the quality of petroleum products. (2) In protecting the environment and, in particular, identifying toxic compounds in fuel oils which, when burned at power stations, emit a substantial number of harmful substances into the atmosphere. (3) In determining commercial by-products, such as vanadium and nickel, in the petroleum and bitumen raw material.

  3. Oxygen Toxicity Calculations by Erik C. Baker, P.E.

    E-Print Network [OSTI]

    Read, Charles

    1 Oxygen Toxicity Calculations by Erik C. Baker, P.E. Management of exposure to oxygen toxicity myself using the good ole' FORTRAN programming language, I found that incorporating oxygen toxicity for others. Background Two oxygen toxicity parameters are typically "tracked" in technical diving

  4. Method for warning of radiological and chemical substances using detection paints on a vehicle surface

    DOE Patents [OSTI]

    Farmer, Joseph C. (Tracy, CA)

    2012-03-13T23:59:59.000Z

    A system for warning of corrosion, chemical, or radiological substances. The system comprises painting a surface with a paint or coating that includes an indicator material and monitoring the surface for indications of the corrosion, chemical, or radiological substances.

  5. ILLEGAL SUBSTANCE ABUSE POLICY San Diego State University recognizes a responsibility to provide a safe

    E-Print Network [OSTI]

    Ponce, V. Miguel

    ILLEGAL SUBSTANCE ABUSE POLICY San Diego State University recognizes a responsibility to provide policy regarding illegal substance abuse. 1.0 Prohibitions San Diego State University prohibits the unlawful manufacture, distribution, dispensation, possession, promotion, sale, or use of illegal drugs

  6. Comparison of standard acute toxicity tests with rapid-screening toxicity tests

    SciTech Connect (OSTI)

    Toussaint, M.W.; Shedd, T.R.; VanDerSchal, W.H.; Leather, G.R.

    1995-10-01T23:59:59.000Z

    This study compared the relative sensitivity of five inexpensive, rapid toxicity tests to the sensitivity of five standard aquatic acute toxicity tests through literature review and testing. The rapid toxicity tests utilized organisms that require little culturing or handling prior to testing: a freshwater rotifer (Branchionus ccalyciflorus); brine shrimp (Artemia salina); lettuce (Lactuca sativa); and two microbial tests (Photo bacterium phosphoreum - Microtox test, and a mixture of bacterial species - the polytox test). Standard acute toxicity test species included water fleas (Daphnia magna and Ceriadaphnta dubia), green algae (Setenastrum capricarnutum), fathead minnows (Pimephalespromelas), and mysid shrimp (Mysidopsis bahia). Sensitivity comparisons between rapid and standard acute toxicity tests were based on LC5O/EC50 data from 11 test chemicals. Individually, the lettuce and rotifer tests ranked most similar in sensitivity to the standard tests, while Microtox fell just outside the range of sensitivities represented by the group of standard acute toxicity tests. The brine shrimp and Polytox tests were one or more orders of magnitude different from the standard acute toxicity tests for most compounds. The lettuce, rotifer, and Microtox tests could be used as a battery for preliminary toxicity screening of chemicals. Further evaluation of complex real-world environmental samples is recommended.

  7. A comparison of standard acute toxicity tests with rapid-screening toxicity tests

    SciTech Connect (OSTI)

    Toussaint, M.W. [Geo-Centers, Inc., Fort Washington, MD (United States); Shedd, T.R. [Army Biomedical Research and Development Lab., Frederick, MD (United States); Schalie, W.H. van der [Environmental Protection Agency, Washington, DC (United States); Leather, G.R. [Hood Coll., Frederick, MD (United States). Dept. of Biology

    1995-05-01T23:59:59.000Z

    This study compared the relative sensitivity of five inexpensive, rapid toxicity tests to the sensitivity of five standard aquatic acute toxicity tests through literature review and testing. The rapid toxicity tests utilized organisms that require little culturing or handling prior to testing: a freshwater rotifer (Branchionus calyciflorus); brine shrimp (Artemia salina); lettuce (Lactuca sativa); and two microbial tests (Photobacterium phosphoreum--Microtox{reg_sign} test, and a mixture of bacterial species--the Polytox{reg_sign} test). Standard acute toxicity test species included water fleas (Daphnia magna and Ceriodaphnia dubia), green algae (Selenastrum capricornutum), fathead minnows (Pimephales promelas), and mysid shrimp (Mysidopsis bahia). Sensitivity comparisons between rapid and standard acute toxicity tests were based on LC50/EC50 data from 11 test chemicals. Individually, the lettuce and rotifer tests ranked most similar in sensitivity to the standard tests, while Microtox fell just outside the range of sensitivities represented by the group of standard acute toxicity tests. The brine shrimp and Polytox tests were one or more orders of magnitude different from the standard acute toxicity tests for most compounds. The lettuce, rotifer, and Microtox tests could be used as a battery for preliminary toxicity screening of chemicals. Further evaluation of complex real-world environmental samples is recommended.

  8. USEtox - The UNEP-SETAC toxicity model: recommended characterisation factors for human toxicity and freshwater ecotoxicity in Life Cycle Impact Assessment

    SciTech Connect (OSTI)

    Rosenbaum, Ralph K.; Bachmann, Till M.; Swirsky Gold, Lois; Huijbregts, Mark A.J.; Jolliet, Olivier; Juraske, Ronnie; Koehler, Annette; Larsen, Henrik F.; MacLeod, Matthew; Margni, Manuele; McKone, Thomas E.; Payet, Jerome; Schuhmacher, Marta; van de Meent, Dik; Hauschild, Michael Z.

    2008-02-03T23:59:59.000Z

    Background, Aim and Scope. In 2005 a comprehensive comparison of LCIA toxicity characterisation models was initiated by the UNEP-SETAC Life Cycle Initiative, directly involving the model developers of CalTOX, IMPACT 2002, USES-LCA, BETR, EDIP, WATSON, and EcoSense. In this paper we describe this model-comparison process and its results--in particular the scientific consensus model developed by the model developers. The main objectives of this effort were (i) to identify specific sources of differences between the models' results and structure, (ii) to detect the indispensable model components, and (iii) to build a scientific consensus model from them, representing recommended practice. Methods. A chemical test set of 45 organics covering a wide range of property combinations was selected for this purpose. All models used this set. In three workshops, the model comparison participants identified key fate, exposure and effect issues via comparison of the final characterisation factors and selected intermediate outputs for fate, human exposure and toxic effects for the test set applied to all models. Results. Through this process, we were able to reduce inter-model variation from an initial range of up to 13 orders of magnitude down to no more than 2 orders of magnitude for any substance. This led to the development of USEtox, a scientific consensus model that contains only the most influential model elements. These were, for example, process formulations accounting for intermittent rain, defining a closed or open system environment, or nesting an urban box in a continental box. Discussion. The precision of the new characterisation factors (CFs) is within a factor of 100-1000 for human health and 10-100 for freshwater ecotoxicity of all other models compared to 12 orders of magnitude variation between the CFs of each model respectively. The achieved reduction of inter-model variability by up to 11 orders of magnitude is a significant improvement.Conclusions. USEtox provides a parsimonious and transparent tool for human health and ecosystem CF estimates. Based on a referenced database, it has now been used to calculate CFs for several thousand substances and forms the basis of the recommendations from UNEP-SETAC's Life Cycle Initiative regarding characterization of toxic impacts in Life Cycle Assessment. Recommendations and Perspectives. We provide both recommended and interim (not recommended and to be used with caution) characterisation factors for human health and freshwater ecotoxicity impacts. After a process of consensus building among stakeholders on a broad scale as well as several improvements regarding a wider and easier applicability of the model, USEtox will become available to practitioners for the calculation of further CFs.

  9. Combined toxicity of four toxicants (Cu, Cr, oil, oil dispersant) to Artemia salina

    SciTech Connect (OSTI)

    Verriopoulos, G.; Moraitou-Apostolopoulou, M.; Milliou, E.

    1987-03-01T23:59:59.000Z

    In sea waters multicontaminant pollution appears to be the rule rather than the exception. For a realistic approach to pollution effects it is essential to estimate the combined toxicity of two or more chemicals. There is a need to understand the mechanisms of quantify the effects of multiple toxicity in order to provide responsible authorities with rational estimate of the effects of chemical mixtures. Thus the potential toxic effects of mixtures of toxicants has recently become a subject of growing scientific interest. In this paper the authors have tried to estimate the joint toxicity of some pollutants commonly found in nearshore polluted waters: two metals, copper and chromium; an oil (Tunesian crude oil zarzaitine type); and an oil dispersant (Finasol OSR-2).

  10. Reduced adsorption of caesium on clay minerals caused by various humic substances

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Reduced adsorption of caesium on clay minerals caused by various humic substances C. Dumat, S!ect of the addition of various humic substances on the adsorption of caesium on two mineral clays has been studied the amount of humic substance adsorbed and the decrease in Cs adsorption when all complexes were considered

  11. Illicit substance detection using fast-neutron interrogation systems

    SciTech Connect (OSTI)

    Yule, T.J.; Micklich, B.J.; Fink, C.L.; Smith, D.L.

    1994-06-01T23:59:59.000Z

    Fast-neutron interrogation techniques are of interest for detecting illicit substances such as explosives and drugs because of their ability to identify light elements such as carbon, nitrogen, and oxygen, which are the primary constituents of these materials. Two particular techniques, Fast-Neutron Transmission Spectroscopy and Pulsed Fast-Neutron Analysis, are discussed. Examples of modeling studies are provided which illustrate the applications of these two techniques.

  12. Forceful Fluid: Scientists Discover a Starchy Substance with Oily Applications

    Broader source: Energy.gov [DOE]

    Researchers at the Energy Department’s Lawrence Livermore National Laboratory (LLNL) set out to find the proper mix of fluids needed to cap the powerful flow of oil that can occur during a spill, an objective that was principally driven by the failure of the top-kill method during last year's oil spill in the Gulf of Mexico. You'll be surprised what starchy substance made the grade.

  13. DOE contractor's meeting on chemical toxicity

    SciTech Connect (OSTI)

    Not Available

    1987-01-01T23:59:59.000Z

    The Office of Health and Environmental Research (OHER) is required to determine the potential health and environmental effects associated with energy production and use. To ensure appropriate communication among investigators and scientific disciplines that these research studies represent, OHER has sponsored workshops. This document provides a compilation of activities at the Third Annual DOE/OHER Workshop. This year's workshop was broadened to include all OHER activities identified as within the chemical effects area. The workshop consisted of eight sessions entitled Isolation and Detection of Toxic chemicals; Adduct Formation and Repair; Chemical Toxicity (Posters); Metabolism and Genotoxicity; Inhalation Toxicology; Gene Regulation; Metals Toxicity; and Biological Mechanisms. This document contains abstracts of the information presented by session.

  14. An inexpensive apparatus for toxicity screening

    SciTech Connect (OSTI)

    Lo Pinto, R.W.; Santelli, J. [Fairleigh Dickinson Univ., Teaneck, NJ (United States)

    1995-12-31T23:59:59.000Z

    An inexpensive apparatus was fabricated to monitor and record changes in the motility patterns of small aquatic invertebrates, such as Artemia salina and Daphnia magna, during acute toxicity tests. Within hours of exposure to a range toxicant concentrations the motility patterns change in a way that predicts the EC50. The work to date suggests there is a correlation between the EC50 following a 60 hour exposure, and motility data collected within the first 40 minutes of the test. The apparatus may be useful to speed range finding tests and for shortening the duration of acute toxicity tests of an effluent or receiving water. The apparatus may also be used to quantify erratic swimming in surviving organisms when a test is terminated.

  15. Ozone-depleting-substance control and phase-out plan

    SciTech Connect (OSTI)

    Nickels, J.M.; Brown, M.J.

    1994-07-01T23:59:59.000Z

    Title VI of the Federal Clean Air Act Amendments of 1990 requires regulation of the use and disposal of ozone-depleting substances (ODSs) (e.g., Halon, Freon). Several important federal regulations have been promulgated that affect the use of such substances at the Hanford Site. On April 23, 1993, Executive Order (EO) 12843, Procurement Requirements and Policies for Federal Agencies for Ozone-Depleting Substances (EPA 1993) was issued for Federal facilities to conform to the new US Environmental Protection Agency (EPA) regulations implementing the Clean Air Act of 1963 (CAA), Section 613, as amended. To implement the requirements of Title VI the US Department of Energy, Richland Operations Office (RL), issued a directive to the Hanford Site contractors on May 25, 1994 (Wisness 1994). The directive assigns Westinghouse Hanford Company (WHC) the lead in coordinating the development of a sitewide comprehensive implementation plan to be drafted by July 29, 1994 and completed by September 30, 1994. The implementation plan will address several areas where immediate compliance action is required. It will identify all current uses of ODSs and inventories, document the remaining useful life of equipment that contains ODS chemicals, provide a phase-out schedule, and provide a strategy that will be implemented consistently by all the Hanford Site contractors. This plan also addresses the critical and required elements of Federal regulations, the EO, and US Department of Energy (DOE) guidance. This plan is intended to establish a sitewide management system to address the clean air requirements.

  16. Method and apparatus for injecting a substance into the bloodstream of a subject

    DOE Patents [OSTI]

    Lambrecht, Richard M. (Quogue, NY); Bennett, Gerald W. (East Moriches, NY); Duncan, Charles C. (New Haven, CT); Ducote, Louis W. (Shoreham, NY)

    1983-10-18T23:59:59.000Z

    An apparatus and method for injecting a substance, such as a radiopharmaceutical, into the bloodstream of a subject. The apparatus comprises an injection means, such as a servo controlled syringe, a means for measuring the concentration of that substance in the subject's bloodstream, and means for controlling the injection in response to the measurement so that the concentration of the substance follows a predetermined function of time. The apparatus of the subject invention functions to inject a substance into a subject's bloodstream at a rate controlled by an error signal proportional to the difference between the concentration of the substance in the subject's bloodstream and the predetermined function.

  17. Method and apparatus for injecting a substance into the bloodstream of a subject

    DOE Patents [OSTI]

    Lambrecht, R.M.; Bennett, G.W.; Duncan, C.C.; Ducote, L.W.

    1983-10-18T23:59:59.000Z

    An apparatus and method is disclosed for injecting a substance, such as a radiopharmaceutical, into the bloodstream of a subject. The apparatus comprises an injection means, such as a servo controlled syringe, a means for measuring the concentration of that substance in the subject's bloodstream, and means for controlling the injection in response to the measurement so that the concentration of the substance follows a predetermined function of time. The apparatus of the subject invention functions to inject a substance into a subject's bloodstream at a rate controlled by an error signal proportional to the difference between the concentration of the substance in the subject's bloodstream and the predetermined function. 2 figs.

  18. Separation of a target substance from a fluid or mixture using encapsulated sorbents

    DOE Patents [OSTI]

    Aines, Roger D; Spadaccini, Christopher M; Stolaroff, Joshuah K; Bourcier, William L; Lewis, Jennifer A; Duoss, Eric B; Vericella, John J

    2014-09-16T23:59:59.000Z

    Method and apparatus for separating a target substance from a fluid or mixture. Capsules having a coating and stripping solvents encapsulated in the capsules are provided. The coating is permeable to the target substance. The capsules having a coating and stripping solvents encapsulated in the capsules are exposed to the fluid or mixture. The target substance migrates through the coating and is taken up by the stripping solvents. The target substance is separated from the fluid or mixture by driving off the target substance from the capsules.

  19. Reference manual for toxicity and exposure assessment and risk characterization. CERCLA Baseline Risk Assessment

    SciTech Connect (OSTI)

    NONE

    1995-03-01T23:59:59.000Z

    The Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA, 1980) (CERCLA or Superfund) was enacted to provide a program for identifying and responding to releases of hazardous substances into the environment. The Superfund Amendments and Reauthorization Act (SARA, 1986) was enacted to strengthen CERCLA by requiring that site clean-ups be permanent, and that they use treatments that significantly reduce the volume, toxicity, or mobility of hazardous pollutants. The National Oil and Hazardous Substances Pollution Contingency Plan (NCP) (USEPA, 1985; USEPA, 1990) implements the CERCLA statute, presenting a process for (1) identifying and prioritizing sites requiring remediation and (2) assessing the extent of remedial action required at each site. The process includes performing two studies: a Remedial Investigation (RI) to evaluate the nature, extent, and expected consequences of site contamination, and a Feasibility Study (FS) to select an appropriate remedial alternative adequate to reduce such risks to acceptable levels. An integral part of the RI is the evaluation of human health risks posed by hazardous substance releases. This risk evaluation serves a number of purposes within the overall context of the RI/FS process, the most essential of which is to provide an understanding of ``baseline`` risks posed by a given site. Baseline risks are those risks that would exist if no remediation or institutional controls are applied at a site. This document was written to (1) guide risk assessors through the process of interpreting EPA BRA policy and (2) help risk assessors to discuss EPA policy with regulators, decision makers, and stakeholders as it relates to conditions at a particular DOE site.

  20. Survey of Geothermal Solid Toxic Waste

    SciTech Connect (OSTI)

    Darnell, A.J.; Gay, R.L.; Klenck, M.M.; Nealy, C.L.

    1982-09-30T23:59:59.000Z

    This is an early survey and analysis of the types and quantities of solid toxic wastes to be expected from geothermal power systems, particularly at the Salton Sea, California. It includes a literature search (48 references/citations), descriptions of methods for handling wastes, and useful quantitative values. It also includes consideration of reclaiming metals and mineral byproducts from geothermal power systems. (DJE 2005)

  1. Sustainable Material Selection of Toxic Chemicals in Design and Manufacturing From Human Health Impact Perspective

    E-Print Network [OSTI]

    Yuan, Chris; Dornfeld, David

    2009-01-01T23:59:59.000Z

    Human Toxicity Potential (HTP) method. Keywords: SustainableHuman Toxicity Potential (HTP) is used for the human healthassessment of toxic chemicals. HTP is a computed weighting

  2. "Human Health Impact Characterization of Toxic Chemicals for Sustainable Design and Manufacturing

    E-Print Network [OSTI]

    Yuan, Chris; Dornfeld, David

    2009-01-01T23:59:59.000Z

    Human toxicity potential (HTP), proposed by Guinée andassessment of toxic chemicals. HTP is a computed weightingmodel environment [5]. The HTP values of toxic chemicals are

  3. Schematic Characterization of Human Health Impact of Toxic Chemicals for Sustainable Design and Manufacturing

    E-Print Network [OSTI]

    Yuan, Chris Y.; Dornfeld, David

    2009-01-01T23:59:59.000Z

    Human Toxicity Potential (HTP) method. With an explicitHuman toxicity potential (HTP), proposed by Guinée andassessment of toxic chemicals. HTP is a computed weighting

  4. Request for interim approval to operate Trench 94 of the 218-E-12B Burial Ground as a chemical waste landfill for disposal of polychlorinated biphenyl waste in submarine reactor compartments. Revision 2

    SciTech Connect (OSTI)

    Cummins, G.D.

    1994-06-01T23:59:59.000Z

    This request is submitted to seek interim approval to operate a Toxic Substances Control Act (TSCA) of 1976 chemical waste landfill for the disposal of polychlorinated biphenyl (PCB) waste. Operation of a chemical waste landfill for disposal of PCB waste is subject to the TSCA regulations of 40 CFR 761. Interim approval is requested for a period not to exceed 5 years from the date of approval. This request covers only the disposal of small 10 quantities of solid PCB waste contained in decommissioned, defueled submarine reactor compartments (SRC). In addition, the request applies only to disposal 12 of this waste in Trench 94 of the 218-E-12B Burial Ground (Trench 94) in the 13 200 East Area of the US Department of Energy`s (DOE) Hanford Facility. Disposal of this waste will be conducted in accordance with the Compliance 15 Agreement (Appendix H) between the DOE Richland Operations Office (DOE-RL) and 16 the US Environmental Protection Agency (EPA), Region 10. During the 5-year interim approval period, the DOE-RL will submit an application seeking final 18 approval for operation of Trench 94 as a chemical waste landfill, including 19 any necessary waivers, and also will seek a final dangerous waste permit from 20 the Washington State Department of Ecology (Ecology) for disposal of lead 21 shielding contained in the SRCS.

  5. Modeling toxic endpoints for improving human health risk assessment

    E-Print Network [OSTI]

    Bruce, Erica Dawn

    2009-05-15T23:59:59.000Z

    Risk assessment procedures for mixtures of polycyclic aromatic hydrocarbons (PAHs) present a problem due to the lack of available potency and toxicity data on mixtures and individual compounds. This study examines the toxicity of parent compound...

  6. Automated process for solvent separation of organic/inorganic substance

    DOE Patents [OSTI]

    Schweighardt, Frank K. (Upper Macungie, PA)

    1986-01-01T23:59:59.000Z

    There is described an automated process for the solvent separation of organic/inorganic substances that operates continuously and unattended and eliminates potential errors resulting from subjectivity and the aging of the sample during analysis. In the process, metered amounts of one or more solvents are passed sequentially through a filter containing the sample under the direction of a microprocessor control apparatus. The mixture in the filter is agitated by ultrasonic cavitation for a timed period and the filtrate is collected. The filtrate of each solvent extraction is collected individually and the residue on the filter element is collected to complete the extraction process.

  7. Automated process for solvent separation of organic/inorganic substance

    DOE Patents [OSTI]

    Schweighardt, F.K.

    1986-07-29T23:59:59.000Z

    There is described an automated process for the solvent separation of organic/inorganic substances that operates continuously and unattended and eliminates potential errors resulting from subjectivity and the aging of the sample during analysis. In the process, metered amounts of one or more solvents are passed sequentially through a filter containing the sample under the direction of a microprocessor control apparatus. The mixture in the filter is agitated by ultrasonic cavitation for a timed period and the filtrate is collected. The filtrate of each solvent extraction is collected individually and the residue on the filter element is collected to complete the extraction process. 4 figs.

  8. Relationship Between Composition and Toxicity of Engine Emission...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Emission Samples Relationship Between Composition and Toxicity of Engine Emission Samples 2003 DEER Conference Presentation: Lovelace Respiratory Research Institute...

  9. REVIEW Open Access Toxic marine microalgae and shellfish poisoning

    E-Print Network [OSTI]

    Hays, Graeme

    REVIEW Open Access Toxic marine microalgae and shellfish poisoning in the British isles: history The relationship between toxic marine microalgae species and climate change has become a high profile and well examine the current state of toxic microalgae species around the UK, in two ways: first we describe

  10. Toxic Contaminants and Their Effects on Resident Fish

    E-Print Network [OSTI]

    Science-Policy Exchange September 10, 2009 #12;Take-away themes Toxic contaminants are present are source areas for toxic contaminants for multiple fish stocks A better understanding of the effects and restore fish and ecosystem health #12;Take-away themes Toxic contaminants are present in the Columbia

  11. Seeing Toxic Algae Before it Blooms By Steve Ress

    E-Print Network [OSTI]

    Nebraska-Lincoln, University of

    Seeing Toxic Algae Before it Blooms By Steve Ress Researchers at the University of Nebraska of toxic blue-green algae before the bacteria that produce it can grow into a full-scale bloom. Now UNL and monitor in real-time, the water-borne agents that can cause toxic blue- green algae to flourish and become

  12. The toxicity of certain new chlorinated hydrocarbons to cotton pests

    E-Print Network [OSTI]

    Merkl, Marvin Eugene

    1953-01-01T23:59:59.000Z

    THE TOXICITY OF CERTAIN NEW CHLORINATED HYDROCARBONS TO COTTON PESTS A Dissertation 5y MARVIN EUGENE MERKL Approved as to style and content by: Chairman of CouBlttee Head of Departnent May 19*3 THE TOXICITY OF CERTAIN NEW CHLORINATED... .....................................................78 CONCLUSIONS............................................... ..81 BIBLIOGRAPHI .............................................. ..82 Pag? FIGURES 1* Dosage-?ortality curve for the toxicity of endrin to aphids...

  13. The toxicity of certain new chlorinated hydrocarbons to cotton pests 

    E-Print Network [OSTI]

    Merkl, Marvin Eugene

    1953-01-01T23:59:59.000Z

    THE TOXICITY OF CERTAIN NEW CHLORINATED HYDROCARBONS TO COTTON PESTS A Dissertation 5y MARVIN EUGENE MERKL Approved as to style and content by: Chairman of CouBlttee Head of Departnent May 19*3 THE TOXICITY OF CERTAIN NEW CHLORINATED... .....................................................78 CONCLUSIONS............................................... ..81 BIBLIOGRAPHI .............................................. ..82 Pag? FIGURES 1* Dosage-?ortality curve for the toxicity of endrin to aphids...

  14. Quantum Brayton cycle with coupled systems as working substance

    E-Print Network [OSTI]

    X. L. Huang; L. C. Wang; X. X. Yi

    2013-01-16T23:59:59.000Z

    We explore the quantum version of Brayton cycle with a composite system as the working substance. The actual Brayton cycle consists of two adiabatic and two isobaric processes. Two pressures can be defined in our isobaric process, one corresponds to the external magnetic field (characterized by $F_x$) exerted on the system, while the other corresponds to the coupling constant between the subsystems (characterized by $F_y$). As a consequence, we can define two types of quantum Brayton cycle for the composite system. We find that the subsystem experiences a quantum Brayton cycle in one quantum Brayton cycle (characterized by $F_x$), whereas the subsystem's cycle is of quantum Otto in another Brayton cycle (characterized by $F_y$). The efficiency for the composite system equals to that for the subsystem in both cases, but the work done by the total system are usually larger than the sum of work done by the two subsystems. The other interesting finding is that for the cycle characterized by $F_y$, the subsystem can be a refrigerator while the total system is a heat engine. The result in the paper can be generalized to a quantum Brayton cycle with a general coupled system as the working substance.

  15. Investigation of single-substance horizontal two-phase flow

    SciTech Connect (OSTI)

    Dickinson, D.A.; Maeder, P.F.

    1984-03-01T23:59:59.000Z

    Despite the abundance of work in the field of two-phase flow, it seems as though a consensus has not been reached on some of the fundamental points. Although exceptions exist, adequate physical interpretation of the flow seems to be hindered either by complexity of analysis or, in the opposite extreme, the trend toward limited-range analysis and correlations. The dissertation presents the derivation of basic conservation equations for the phases. The combined equations are used to examine the phenomenon of slip and its practical limitations, the Fanno line for single-substance flow and the effect of slip on choking. Equations for critical mass flux in the presence of slip are derived. The Mach, Reynolds and Froude numbers based on conditions at flashing are introduced as the characteristic parameters, and the importance of compressibility in single-substance two-phase flow is discussed. Experimental measurements of pressure change and void fraction for flow in the highly compressible range (.5 < Ma < 1) are presented. The working fluid is Refrigerant R-114, at room temperature, in a test section of diameter 5 cm and length 8 m. The effect of the Froude and Mach numbers is examined. The experimental facility is operated intermittently with running times of approximately two minutes and is instrumented for rapid measurements using a computer data acquisition and control system. A description of the facility and procedure is provided.

  16. Regulatory requirements affecting disposal of asbestos-containing waste

    SciTech Connect (OSTI)

    NONE

    1995-11-01T23:59:59.000Z

    Many U.S. Department of Energy (DOE) facilities are undergoing decontamination and decommissioning (D&D) activities. The performance of these activities may generate asbestos-containing waste because asbestos was formerly used in many building materials, including floor tile, sealants, plastics, cement pipe, cement sheets, insulating boards, and insulating cements. The regulatory requirements governing the disposal of these wastes depend on: (1) the percentage of asbestos in the waste and whether the waste is friable (easily crumbled or pulverized); (2) other physical and chemical characteristics of the waste; and (3) the State in which the waste is generated. This Information Brief provides an overview of the environment regulatory requirements affecting disposal of asbestos-containing waste. It does not address regulatory requirements applicable to worker protection promulgated under the Occupational Safety and Health Act (OSHAct), the Mining Safety and Health Act (MSHA), or the Toxic Substances Control Act (TSCA).

  17. Tank 241-AP-106, Grab samples, 6AP-98-1, 6AP-98-2 and 6AP-98-3 Analytical results for the final report

    SciTech Connect (OSTI)

    FULLER, R.K.

    1999-02-23T23:59:59.000Z

    This document is the final report for tank 241-AP-106 grab samples. Three grab samples 6AP-98-1, 6AP-98-2 and 6AP-98-3 were taken from riser 1 of tank 241-AP-106 on May 28, 1998 and received by the 222-S Laboratory on May 28, 1998. Analyses were performed in accordance with the ''Compatability Grab Sampling and Analysis Plan'' (TSAP) (Sasaki, 1998) and the ''Data Quality Objectives for Tank Farms Waste Compatability Program (DQO). The analytical results are presented in the data summary report. No notification limits were exceeded. The request for sample analysis received for AP-106 indicated that the samples were polychlorinated biphenyl (PCB) suspects. The results of this analysis indicated that no PCBs were present at the Toxic Substance Control Act (TSCA) regulated limit of 50 ppm. The results and raw data for the PCB analysis are included in this document.

  18. Environmental Compliance at the West Valley Demonstration Project: The Vitrification Permitting Program

    SciTech Connect (OSTI)

    L. C. Salvatori; C. B. Banzer; W. T. Watters

    1996-05-28T23:59:59.000Z

    The major environmental laws that apply to the West Valley Demonstration Project (WVDP) are the: Resource Conservation and Recovery Act (RCRA), Clean Air Act (CAA), Clean Water Act (CWA), Safe Drinking Water Act (SDWA), Toxic Substances Control Act (TSCA), National Environmental Policy Act (NEPA), and Emergency Planning and Community Right-To-Know Act (EPCRA). Regulations developed in accordance with these laws are administered by the New York State Department of Environmental Conservation (NYSDEC) and the U.S. Environmental Protection Agency (EPA) through state and federal programs, and regulatory requirements such as permitting. The Environmental Permits & Reports (EP&R) Group of the Environmental Affairs (EA) Department has the primary responsibility for developing a site-wide permitting program for the WVDP and obtaining the necessary permits. This report discusses the permits and the permitting process associated with the Vitrification Facility (VF).

  19. Toxic species evolution from guayule fireplace logs

    E-Print Network [OSTI]

    Soderman, Kristi Lee

    1988-01-01T23:59:59.000Z

    and cellulosic material from bagasse are generated as co-products of rubber extraction. The cellulosic material uses which are favored at this time require combustion. Bagasse affords the potential for use as biomass fuel in the production of process steam... of chromium, if present in the hexavalent state, no unusually toxic constituents were found in the smoke particulates, gaseous state or as condensible liquids for flaming and smoldering combustion of guayule fireplace logs. Butylhydroxytoluene (BHT), a...

  20. Toxicity Data to Determine Refrigerant Concentration Limits

    SciTech Connect (OSTI)

    Calm, James M.

    2000-09-30T23:59:59.000Z

    This report reviews toxicity data, identifies sources for them, and presents resulting exposure limits for refrigerants for consideration by qualified parties in developing safety guides, standards, codes, and regulations. It outlines a method to calculate an acute toxicity exposure limit (ATEL) and from it a recommended refrigerant concentration limit (RCL) for emergency exposures. The report focuses on acute toxicity with particular attention to lethality, cardiac sensitization, anesthetic and central nervous system effects, and other escape-impairing effects. It addresses R-11, R-12, R-22, R-23, R-113, R-114, R-116, R-123, R-124, R-125, R-134, R-134a, R-E134, R-141b, R-142b, R-143a, R-152a, R-218, R-227ea, R-236fa, R-245ca, R-245fa, R-290, R-500, R-502, R-600a, R-717, and R-744. It summarizes additional data for R-14, R-115, R-170 (ethane), R-C318, R-600 (n-butane), and R-1270 (propylene) to enable calculation of limits for blends incorporating them. The report summarizes the data a nd related safety information, including classifications and flammability data. It also presents a series of tables with proposed ATEL and RCL concentrations-in dimensionless form and the latter also in both metric (SI) and inch-pound (IP) units of measure-for both the cited refrigerants and 66 zerotropic and azeotropic blends. They include common refrigerants, such as R-404A, R-407C, R-410A, and R-507A, as well as others in commercial or developmental status. Appendices provide profiles for the cited single-compound refrigerants and for R-500 and R-502 as well as narrative toxicity summaries for common refrigerants. The report includes an extensive set of references.

  1. Hydrogen and Gaseous Fuel Safety and Toxicity

    SciTech Connect (OSTI)

    Lee C. Cadwallader; J. Sephen Herring

    2007-06-01T23:59:59.000Z

    Non-traditional motor fuels are receiving increased attention and use. This paper examines the safety of three alternative gaseous fuels plus gasoline and the advantages and disadvantages of each. The gaseous fuels are hydrogen, methane (natural gas), and propane. Qualitatively, the overall risks of the four fuels should be close. Gasoline is the most toxic. For small leaks, hydrogen has the highest ignition probability and the gaseous fuels have the highest risk of a burning jet or cloud.

  2. Hazardous-Substance Generator, Transporter and Disposer Liability under the Federal and California Superfunds

    E-Print Network [OSTI]

    Vernon, James; Dennis, Patrick W.

    1981-01-01T23:59:59.000Z

    Carpenter-Presley-Tanner Hazardous Substance Account Act ofincluding spills and hazardous- waste disposal sites thatlabel for the disposal of hazardous wastes. Id. at 607. The

  3. Yellow phosphorus process to convert toxic chemicals to non-toxic products

    DOE Patents [OSTI]

    Chang, Shih-Ger (El Cerrito, CA)

    1994-01-01T23:59:59.000Z

    The present invention relates to a process for generating reactive species for destroying toxic chemicals. This process first contacts air or oxygen with aqueous emulsions of molten yellow phosphorus. This contact results in rapid production of abundant reactive species such as O, O.sub.3, PO, PO.sub.2, etc. A gaseous or liquid aqueous solution organic or inorganic chemicals is next contacted by these reactive species to reduce the concentration of toxic chemical and result in a non-toxic product. The final oxidation product of yellow phosphorus is phosphoric acid of a quality which can be recovered for commercial use. A process is developed such that the byproduct, phosphoric acid, is obtained without contamination of toxic species in liquids treated. A gas stream containing ozone without contamination of phosphorus containing species is also obtained in a simple and cost-effective manner. This process is demonstrated to be effective for destroying many types of toxic organic, or inorganic, compounds, including polychlorinated biphenyls (PCB), aromatic chlorides, amines, alcohols, acids, nitro aromatics, aliphatic chlorides, polynuclear aromatic compounds (PAH), dyes, pesticides, sulfides, hydroxyamines, ureas, dithionates and the like.

  4. Yellow phosphorus process to convert toxic chemicals to non-toxic products

    DOE Patents [OSTI]

    Chang, S.G.

    1994-07-26T23:59:59.000Z

    The present invention relates to a process for generating reactive species for destroying toxic chemicals. This process first contacts air or oxygen with aqueous emulsions of molten yellow phosphorus. This contact results in rapid production of abundant reactive species such as O, O[sub 3], PO, PO[sub 2], etc. A gaseous or liquid aqueous solution organic or inorganic chemicals is next contacted by these reactive species to reduce the concentration of toxic chemical and result in a non-toxic product. The final oxidation product of yellow phosphorus is phosphoric acid of a quality which can be recovered for commercial use. A process is developed such that the byproduct, phosphoric acid, is obtained without contamination of toxic species in liquids treated. A gas stream containing ozone without contamination of phosphorus containing species is also obtained in a simple and cost-effective manner. This process is demonstrated to be effective for destroying many types of toxic organic, or inorganic, compounds, including polychlorinated biphenyls (PCB), aromatic chlorides, amines, alcohols, acids, nitro aromatics, aliphatic chlorides, polynuclear aromatic compounds (PAH), dyes, pesticides, sulfides, hydroxyamines, ureas, dithionates and the like. 20 figs.

  5. WELFARE REFORM, SUBSTANCE USE, AND MENTAL HEALTH1 Rukmalie Jayakody2

    E-Print Network [OSTI]

    Shyy, Wei

    1 WELFARE REFORM, SUBSTANCE USE, AND MENTAL HEALTH1 Rukmalie Jayakody2 Pennsylvania State for useful comments that improved our paper. #12;3 ABSTRACT Welfare reform transformed the traditional-sufficiency that are increasingly important in this era of time-limited benefits. KEYWORDS: welfare reform, substance abuse, mental

  6. Ozone-depleting substances and the greenhouse gases HFCs, PFCs and

    E-Print Network [OSTI]

    Ozone-depleting substances and the greenhouse gases HFCs, PFCs and SF6 Danish consumption contribution to the debate on environmental policy in Denmark. #12;3 Contents 1 SUMMARY 5 1.1 OZONE OZONE-DEPLETING SUBSTANCES 18 3.1 IMPORTS AND EXPORTS 18 3.1.1 CFCs 18 3.1.2 Tetrachloromethane 19 3

  7. Carbonaceous species and humic like substances (HULIS) in Arctic snowpack during OASIS field campaign in Barrow

    E-Print Network [OSTI]

    Sheldon, Nathan D.

    Carbonaceous species and humic like substances (HULIS) in Arctic snowpack during OASIS field on snow albedo and arctic atmospheric chemistry. During the OASIS field campaign, in March and April 2009), Carbonaceous species and humic like substances (HULIS) in Arctic snowpack during OASIS field campaign in Barrow

  8. Funding Opportunity: Superfund Hazardous Substance Research and Training Program Sponsor: National Institute of Health

    E-Print Network [OSTI]

    Suzuki, Masatsugu

    Funding Opportunity: Superfund Hazardous Substance Research and Training Program (P42) Sponsor Sciences (NIEHS) is announcing the continuation of the Superfund Hazardous Substance Research and Training techniques for the detection, assessment, and evaluation of the effect on human health of hazardous

  9. Funding Opportunity: Superfund Hazardous Substance Research and Training Program (P42)

    E-Print Network [OSTI]

    Suzuki, Masatsugu

    Funding Opportunity: Superfund Hazardous Substance Research and Training Program (P42) Sponsor (NIEHS) is announcing the continuation of the Superfund Hazardous Substance Research and Training Program techniques for the detection, assessment, and evaluation of the effect on human health of hazardous

  10. New data on the characterization of humic substances extracted from phosphatised faecal "pellets" (Tunisia)

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    New data on the characterization of humic substances extracted from phosphatised faecal "pellets, Université Tunis El Manar, 1060, Tunis, Tunisie Humic substances (HS) were extracted from faecal "pellets of the organic matter within the pellets, both from a qualitative and quantitative point of view. The elemental

  11. Social Welfare Policy and Public Assistance for Low-Income Substance Abusers

    E-Print Network [OSTI]

    de Lijser, Peter

    income and health care benefits for many low- income substance abusers. This paper examines functioning has been a point of contention among politicians, physicians, and sub- stance abuse treatment. Individuals with substan- tiated claims were mandated to substance abuse treatment, to having a representative

  12. National and Regional Resources Substance Abuse and Mental Health Services Administration

    E-Print Network [OSTI]

    Acton, Scott

    to carry-out voucher programs for substance abuse clinical treatment and recovery support services. GoalRecovery National and Regional Resources Substance Abuse and Mental Health Services Administration SAMHSA: Recovery is a primary goal for behavioral health care Recovery has been identified as a primary

  13. Uranium Exerts Acute Toxicity by Binding to Pyrroloquinoline Quinone Cofactor

    SciTech Connect (OSTI)

    Michael R. VanEngelen; Robert I. Szilagyi; Robin Gerlach; Brady E. Lee; William A. Apel; Brent M. Peyton

    2011-02-01T23:59:59.000Z

    Uranium as an environmental contaminant has been shown to be toxic to eukaryotes and prokaryotes; however, no specific mechanisms of uranium toxicity have been proposed so far. Here a combination of in vivo, in vitro, and in silico studies are presented describing direct inhibition of pyrroloquinoline quinone (PQQ)-dependent growth and metabolism by uranyl cations. Electrospray-ionization mass spectroscopy, UV-vis optical spectroscopy, competitive Ca2+/uranyl binding studies, relevant crystal structures, and molecular modeling unequivocally indicate the preferred binding of uranyl simultaneously to the carboxyl oxygen, pyridine nitrogen, and quinone oxygen of the PQQ molecule. The observed toxicity patterns are consistent with the biotic ligand model of acute metal toxicity. In addition to the environmental implications, this work represents the first proposed molecular mechanism of uranium toxicity in bacteria, and has relevance for uranium toxicity in many living systems.

  14. Review The Toxicity of Depleted Uranium

    E-Print Network [OSTI]

    Wayne Briner

    Abstract: Depleted uranium (DU) is an emerging environmental pollutant that is introduced into the environment primarily by military activity. While depleted uranium is less radioactive than natural uranium, it still retains all the chemical toxicity associated with the original element. In large doses the kidney is the target organ for the acute chemical toxicity of this metal, producing potentially lethal tubular necrosis. In contrast, chronic low dose exposure to depleted uranium may not produce a clear and defined set of symptoms. Chronic low-dose, or subacute, exposure to depleted uranium alters the appearance of milestones in developing organisms. Adult animals that were exposed to depleted uranium during development display persistent alterations in behavior, even after cessation of depleted uranium exposure. Adult animals exposed to depleted uranium demonstrate altered behaviors and a variety of alterations to brain chemistry. Despite its reduced level of radioactivity evidence continues to accumulate that depleted uranium, if ingested, may pose a radiologic hazard. The current state of knowledge concerning DU is discussed.

  15. The toxicity of different emulsions of toxaphene to cotton insects

    E-Print Network [OSTI]

    Selby, James Winford

    1952-01-01T23:59:59.000Z

    . Summary of the cotton boll weevil toxicity tests ~ . LS 5. Analysis of cotton bolL weevil control data ob- tained in the laboratory and field teste ~ ~ ~ ~ ~ 20 4 ~ Summary of the cotton boll weevil toxicity test in the Laboratorye ~ ~ ~ ~ ~ ~ ~ ~ e... ~ ~ ~ ~ ~ ~ ~ ~ o ~ ~ e ~ ~ ~ ~ ~ ~ ~ ~ 21 6 Summary of the saltish caterpillar toxicity tests ~ ~ ~ eo ~ ~ ~ ~ ~ e( ~ ~ ~ ~ ~ ~ ee ~ ~ ~ ~ ~ ~ o ~ ~ ~ ~ ~ ~ ~ e ~ a ~ ~ ~ ~ ~ 22 6 ~ Vedian lethal dosage {KID) of the test materials as obtained fran the Laboratory...

  16. Identification of toxic components in beechwood and petroleum creosotes

    E-Print Network [OSTI]

    Okaygun, Mehmet S.

    1988-01-01T23:59:59.000Z

    the formulation of mixtures which confer wood preservation properties but which minimize health risks. Before a chemical can be used in the industry, whole animal toxicity testing is required. This consists of acute toxicity testing, repeated dose toxicity...-induced rat liver homogenate (S-9 fraction) for activation. Dose related increases in mutation frequencies were reported for both test chemicals following metabolic acti- vation. However, without metabolic activation, the mutagenic frequency...

  17. The toxicity of different emulsions of toxaphene to cotton insects 

    E-Print Network [OSTI]

    Selby, James Winford

    1952-01-01T23:59:59.000Z

    . Summary of the cotton boll weevil toxicity tests ~ . LS 5. Analysis of cotton bolL weevil control data ob- tained in the laboratory and field teste ~ ~ ~ ~ ~ 20 4 ~ Summary of the cotton boll weevil toxicity test in the Laboratorye ~ ~ ~ ~ ~ ~ ~ ~ e... ~ ~ ~ ~ ~ ~ ~ ~ o ~ ~ e ~ ~ ~ ~ ~ ~ ~ ~ 21 6 Summary of the saltish caterpillar toxicity tests ~ ~ ~ eo ~ ~ ~ ~ ~ e( ~ ~ ~ ~ ~ ~ ee ~ ~ ~ ~ ~ ~ o ~ ~ ~ ~ ~ ~ ~ e ~ a ~ ~ ~ ~ ~ 22 6 ~ Vedian lethal dosage {KID) of the test materials as obtained fran the Laboratory...

  18. alleviates ammonium toxicity: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    actinomycetes. When... Morales-Bermudez, Marciano 2012-06-07 115 In vitro toxicity assessment of chitosan nanoparticles. Open Access Theses and Dissertations Summary:...

  19. agent toxicity testing: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Tristan Behrens, Koen Hindriks, Jomi Hbner, Mehdi Dastani Abstract It is our goal Zachmann, Gabriel 5 766 Combinatorial QSAR Modeling of Chemical Toxicants Tested against...

  20. acute toxicity assessment: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    in this technology, and the products constructed from nanoparticulates is an emerging area in toxicology and health risk assessment. The development of toxicity data sets and...

  1. acetaminophen toxicity evidence: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    - No national standards - Less Bertini, Robert L. 17 Review The Toxicity of Depleted Uranium CiteSeer Summary: Abstract: Depleted uranium (DU) is an emerging...

  2. acute toxic radiation: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    vole Population genetics Comparative Baker, Robert J. 39 Review The Toxicity of Depleted Uranium CiteSeer Summary: Abstract: Depleted uranium (DU) is an emerging environmental...

  3. acute urinary toxicity: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    they generally lack sufficient dis Cunningham, Ian 39 Review The Toxicity of Depleted Uranium CiteSeer Summary: Abstract: Depleted uranium (DU) is an emerging environmental...

  4. acute acetaminophen toxicity: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    conduct, may therefore underestimate Rosenheim, Jay A. 36 Review The Toxicity of Depleted Uranium CiteSeer Summary: Abstract: Depleted uranium (DU) is an emerging environmental...

  5. acute toxic encephalopathy: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    conduct, may therefore underestimate Rosenheim, Jay A. 42 Review The Toxicity of Depleted Uranium CiteSeer Summary: Abstract: Depleted uranium (DU) is an emerging environmental...

  6. acute toxicity: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    conduct, may therefore underestimate Rosenheim, Jay A. 27 Review The Toxicity of Depleted Uranium CiteSeer Summary: Abstract: Depleted uranium (DU) is an emerging environmental...

  7. acute acrolein toxicity: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    conduct, may therefore underestimate Rosenheim, Jay A. 36 Review The Toxicity of Depleted Uranium CiteSeer Summary: Abstract: Depleted uranium (DU) is an emerging environmental...

  8. ORNL 99-04743/arb 1. K-1435 TSCA Incinerator

    E-Print Network [OSTI]

    Pennycook, Steve

    KAFaD Laundry 14. K-1066-E UF6 Cylinder Venting 15. K-1065-D Waste Downblending 15 1 2 5 7 12 13 14 10

  9. System and method for preconcentrating, identifying, and quantifying chemical and biological substances

    DOE Patents [OSTI]

    Yu, Conrad M. (Antioch, CA); Koo, Jackson C. (San Ramon, CA)

    2000-01-01T23:59:59.000Z

    A system and method for preconcentrating, identifying, and quantifying chemical and biological substances is disclosed. An input valve directs a first volume of a sample gas to a surface acoustic wave (SAW) device. The SAW device preconcentrates and detects a mass of a substance within the sample gas. An output valve receives a second volume of the sample gas containing the preconcentrated substance from the SAW device and directs the second volume to a gas chromatograph (GC). The GC identifies the preconcentrated substance within the sample gas. A shunt valve exhausts a volume of the sample gas equal to the first volume minus the second volume away from the SAW device and the GC. The method of the present invention includes the steps of opening an input valve for passing a first volume of a sample gas to a SAW device; preconcentrating and detecting a mass of a substance within the sample gas using the SAW device; opening an output valve for passing a second volume of the sample gas containing the preconcentrated substance to a gas chromatograph (GC); and then identifying the preconcentrated substance within the sample gas using the GC.

  10. Toxic chemical considerations for tank farm releases

    SciTech Connect (OSTI)

    Van Keuren, J.C.; Davis, J.S., Westinghouse Hanford

    1996-08-01T23:59:59.000Z

    This topical report contains technical information used to determine the accident consequences of releases of toxic chemical and gases for the Tank Farm Final Safety Analysis report (FSAR).It does not provide results for specific accident scenarios but does provide information for use in those calculations including chemicals to be considered, chemical concentrations, chemical limits and a method of summing the fractional contributions of each chemical. Tank farm composites evaluated were liquids and solids for double shell tanks, single shell tanks, all solids,all liquids, headspace gases, and 241-C-106 solids. Emergency response planning guidelines (ERPGs) were used as the limits.Where ERPGs were not available for the chemicals of interest, surrogate ERPGs were developed. Revision 2 includes updated sample data, an executive summary, and some editorial revisions.

  11. Assessing the potential toxicity of resuspended sediment

    SciTech Connect (OSTI)

    Bonnet, C.; Babut, M.; Ferard, J.F.; Martel, L.; Garric, J.

    2000-05-01T23:59:59.000Z

    Two moderately contaminated freshwater sediments (Sorel Harbour, St. Lawrence River, Canada) were subjected to a suspension event. The objective was to assess the environmental impact of the disposal of dredged material in water, in particular, the short-term effects of dumping on the water column and the long-term effects of dredged sediment deposits. In a series of microcosms, the sediments were left to stand for 25 d under flow-through conditions. In a second series of microcosms, sediments were vigorously suspended for 15 min before being left to settle and were submitted to the same treatment as reference sediments during the following 25 d. Physicochemical and biological parameters (Daphnia magna and Hydra attenuata survival) were measured in overlying water throughout the experiment. Sediment toxicity was assessed with Chironomus tentans and Hyalella azteca exposed to sediments collected at both the beginning and end of the 25-d period. Pore-water toxicity was evaluated with D. magna. During the suspension process, in the Sorel Harbour mixed sediment overlying water, the authors observed effects on H. attenuata survival and ammonia and metals (chromium, copper, and zinc) releases. Meanwhile, in reference (nonmixed) and mixed sediments as well as in associated pore waters, there were no significant chemical modifications no biological effects after the 25-d experiments. The developed approach, which attempts to simulate a dumping process, aims at allowing the assessment of the short- and long-term hazards resulting from a resuspension process in overlying water and in resettled sediments using both chemical and biological measurements.

  12. acute toxicity test: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    toxicity test First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 The weaker points of fish acute toxicity...

  13. Evaluation of Sediment Toxicity Using a Suite of Assessment Tools

    E-Print Network [OSTI]

    Kelley, Matthew A

    2010-01-15T23:59:59.000Z

    of sediment toxicity. The goal of this research was to provide information which could help increase the accuracy with which predictions of toxicity could be made at hazardous sites. A calibration study was conducted using model PAHs, PCBs, a binary PAH...

  14. Relative Leaching and Aquatic Toxicity of Pressure-Treated Wood

    E-Print Network [OSTI]

    Florida, University of

    Relative Leaching and Aquatic Toxicity of Pressure-Treated Wood Products Using Batch Leaching Tests treated with one of five different waterborne chemical preservatives, were leached using 18-h batch- treated wood at concentrations above the U.S. federal toxicity characteristic limit (5 mg/L). All

  15. A Strategy for Designing Inhibitors of -Amyloid Toxicity*

    E-Print Network [OSTI]

    Kiessling, Laura

    patients (1, 2). The deposition of A in the form of amyloid fibrils is believed by many to be causally aggregated into amyloid fibrils, the peptide is toxic to neuronal cells. Here, an approach to the design of amyloid fibril formation is not necessary for abrogation of toxicity. -Amyloid peptide (A )1 is the major

  16. Aquatic Toxicity Information Retrieval Data Base (ACQUIRE). Data file

    SciTech Connect (OSTI)

    Not Available

    1991-09-01T23:59:59.000Z

    The purpose of Acquire is to provide scientists and managers quick access to a comprehensive, systematic, computerized compilation of aquatic toxicity data. Scientific papers published both nationally and internationally on the toxicity of chemicals to aquatic organisms and plants are collected and reviewed for ACQUIRE. Independently compiled data files that meet ACQUIRE parameter and quality assurance criteria are also included. Selected toxicity test results and related testing information for any individual chemical from laboratory and field aquatic toxicity effects are included for tests with freshwater and marine organisms. The total number of data records in ACQUIRE is now over 105,300. This includes data from 6000 references, for 5200 chemicals and 2400 test species. A major data file, Acute Toxicity of Organic Chemicals (ATOC), has been incorporated into ACQUIRE. The ATOC file contains laboratory acute test data on 525 organic chemicals using juvenile fathead minnows.

  17. Guidelines for Transportation, Handling, and Use of Fast Pyrolysis Bio-Oil. Part 1. Flammability and Toxicity

    SciTech Connect (OSTI)

    Oasmaa, Anja; Kalli, Anssi; Lindfors, Christian; Elliott, Douglas C.; Springer, David L.; Peacocke, Cordner; Chiaramonti, David

    2012-05-04T23:59:59.000Z

    An alternative sustainable fuel, biomass-derived fast pyrolysis oil or 'bio-oil', is coming into the market. Fast pyrolysis pilot and demonstration plants for fuel applications producing tonnes of bio-oil are in operation, and commercial plants are under design. There will be increasingly larger amounts of bio-oil transportation on water and by land, leading to a need for specifications and supporting documentation. Bio-oil is different from conventional liquid fuels, and therefore must overcome both technical and marketing hurdles for its acceptability in the fuels market. A comprehensive Material Safety Data Sheet (MSDS) is required, backed with independent testing and certification. In order to standardise bio-oil quality specifications are needed. The first bio-oil burner fuel standard in ASTM (D7544) was approved in 2009. CEN standardisation has been initiated in Europe. In the EU a new chemical regulation system, REACH (Registration, Evaluation and Authorisation of Chemicals) is being applied. Registration under REACH has to be made if bio-oil is produced or imported to the EU. In the USA and Canada, bio-oil has to be filed under TOSCA (US Toxic Substances Control Act). In this paper the state of the art on standardisation is discussed, and new data for the transportation guidelines is presented. The focus is on flammability and toxicity.

  18. Human intake fraction of toxic pollutants: a model comparison between caltox and uses-lca

    SciTech Connect (OSTI)

    Huijbregts, Mark A.J.; Geelen, Loes M.J.; Hertwich, Edgar G.; McKone, Thomas E.; van de Meent, Dik

    2004-01-06T23:59:59.000Z

    In Life Cycle Assessment and Comparative Risk Assessment potential human exposure to toxic pollutants can be expressed as the human intake fraction (iF), representing the fraction of the quantity emitted that enters the human population. To assess model uncertainty in the human intake fraction, ingestion and inhalation iFs of 367 substances emitted to air and freshwater were calculated with two commonly applied multi-media fate and exposure models, CalTOX and USES-LCA. Comparison of the model outcomes reveal that uncertainty in the ingestion iFs was up to a factor of 70. The uncertainty in the inhalation iFs was up to a factor of 865,000. The comparison showed that relatively few model differences account for the uncertainties found. An optimal model structure in the calculation of human intake fractions can be achieved by including (1) rain and no-rain scenarios, (2) a continental sea water compartment, (3) drinking water purification, (4) pH-correction of chemical properties, and (5) aerosol-associated deposition on plants. Finally, vertical stratification of the soil compartment combined with a chemical-dependent soil depth may be considered in future intake fraction calculations.

  19. Stone cold clean & dry : a substance abuse rehab center In Manhattan

    E-Print Network [OSTI]

    Hagen-Cazes, Charlie Byrd

    2010-01-01T23:59:59.000Z

    Joseph Califano, founder and president of The National Center on Addiction and Substance Abuse (CASA) at Columbia University, declares drug an alcohol abuse the causes and contributor to "just about every intractable problem ...

  20. Role of viscosity in the accurate prediction of source-terms for high molecular weight substances

    E-Print Network [OSTI]

    Shaikh, Irfan Yusuf

    1999-01-01T23:59:59.000Z

    This study shows that using better material property predictions results in better source-term modeling for high molecular weight substances. Viscosity, density, and enthalpy are used as a function of process variables, namely, temperature...

  1. Grandparenting in the 21st Problems such as substance abuse, catastrophic illness, teen pregnancy, incarceration, unemployment,

    E-Print Network [OSTI]

    Grandparenting in the 21st Century Problems such as substance abuse, catastrophic illness, teen. The following information from the Texas A&M AgriLife Extension Service may be helpful Take Care of Yourself

  2. anti-proliferative substance taurolidine: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    or ex-partners, so the term woman abuse will be used throughout this paper. Larry W. Bennett 8 A question of substance MIT - DSpace Summary: During the week of January 27th to...

  3. RELATIONSHIP BETWEEN COMPOSITION AND TOXICITY OF ENGINE EMISSION SAMPLES

    SciTech Connect (OSTI)

    (1)Mauderly, J; Seagrave, J; McDonald; J (2)Eide,I (3)Zielinska, B (4)Lawson, D

    2003-08-24T23:59:59.000Z

    Differences in the lung toxicity and bacterial mutagenicity of seven samples from gasoline and diesel vehicle emissions were reported previously [1]. Filter and vapor-phase semivolatile organic samples were collected from normal and high-emitter gasoline and diesel vehicles operated on chassis dynamometers on the Unified Driving Cycle, and the compositions of the samples were measured in detail. The two fractions of each sample were combined in their original mass collection ratios, and the toxicity of the seven samples was compared by measuring inflammation and tissue damage in rat lungs and mutagenicity in bacteria. There was good agreement among the toxicity response variables in ranking the samples and demonstrating a five-fold range of toxicity. The relationship between chemical composition and toxicity was analyzed by a combination of principal component analysis (PCA) and partial least squares regression (PLS, also known as projection to latent surfaces). The PCA /PLS analysis revealed the chemical constituents co-varying most strongly with toxicity and produced models predicting the relative toxicity of the samples with good accuracy. The results demonstrated the utility of the PCA/PLS approach, which is now being applied to additional samples, and it also provided a starting point for confirming the compounds that actually cause the effects.

  4. Lung Toxicity and Mutagenicity of Emissions From Heavy-Duty Compressed...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Lung Toxicity and Mutagenicity of Emissions From Heavy-Duty Compressed Natural Gas (CNG)-Powered Vehicles Lung Toxicity and Mutagenicity of Emissions From Heavy-Duty Compressed...

  5. The subchronic toxicity of Roridin A in sheep

    E-Print Network [OSTI]

    Thormahlen, Keller Andrew

    1988-01-01T23:59:59.000Z

    THE SUBCKKNIC TOXICITY OF BORIDIN A IN SHEEP A Thesis Submitted to the Graduate College of Texas A & M University in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE August 1988 Major Subject: Toxicology THE SDBC...(BKKIC TOXICITY OF RORIDIN A IN SHEEP A Thesis Approved as to style and content by: E. 1. Bailey, Jr (Chairman of Committee) Bennie J. (~) z. P Timo y D. Hu. llips (~) J. D. McCrady (Head of Department) August 1988 The Subchronic Toxicity of Roridin A...

  6. The subchronic toxicity of Roridin A in sheep 

    E-Print Network [OSTI]

    Thormahlen, Keller Andrew

    1988-01-01T23:59:59.000Z

    THE SUBCKKNIC TOXICITY OF BORIDIN A IN SHEEP A Thesis Submitted to the Graduate College of Texas A & M University in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE August 1988 Major Subject: Toxicology THE SDBC...(BKKIC TOXICITY OF RORIDIN A IN SHEEP A Thesis Approved as to style and content by: E. 1. Bailey, Jr (Chairman of Committee) Bennie J. (~) z. P Timo y D. Hu. llips (~) J. D. McCrady (Head of Department) August 1988 The Subchronic Toxicity of Roridin A...

  7. Air Pollution Control Regulations: No. 22- Air Toxics (Rhode Island)

    Broader source: Energy.gov [DOE]

    Permits are required to construct, install, or modify any stationary source which has the potential to increase emissions of a listed toxic air contaminant by an amount greater than the minimum...

  8. acid toxicity tolerance: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    dimensions into chains 60 Some factors in liquid supplements affecting urea toxicity Texas A&M University - TxSpace Summary: in ruminants. Sheep and cattle were drenched with...

  9. air toxic emissions: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Page Topic Index 1 Zhao, Y., and H.C. Frey, "Development of Probabilistic Emission Inventory of Air Toxics for Jacksonville, FL," Proceedings, Annual Meeting of the Air & Waste...

  10. air toxics emission: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Page Topic Index 1 Zhao, Y., and H.C. Frey, "Development of Probabilistic Emission Inventory of Air Toxics for Jacksonville, FL," Proceedings, Annual Meeting of the Air & Waste...

  11. air toxics emissions: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Page Topic Index 1 Zhao, Y., and H.C. Frey, "Development of Probabilistic Emission Inventory of Air Toxics for Jacksonville, FL," Proceedings, Annual Meeting of the Air & Waste...

  12. Electrically Heated High Temperature Incineration of Air Toxics

    E-Print Network [OSTI]

    Agardy, F. J.; Wilcox, J. B.

    In-Process Technology has placed a prototype of its patented, electrically heated, packed-bed air toxics oxidizer at a northern California chemical plant. This thermal oxidizer is capable of handling a wide range of chlorinated and non...

  13. Toxicity studies with Sesbania spp. in domestic and laboratory animals

    E-Print Network [OSTI]

    Whall, Jeffrey DePass

    1982-01-01T23:59:59.000Z

    May 1982 Major Subject: Veterinary Toxicology TOXICITY STUDIES WITH SESBANIA SPP. IN DOMESTIC AND LABORATORY ANIMALS A Thesis by JEFFREY DEPASS WHALL Approved as to style and content by: (- ~ -) Chy an of Comm ttee) Head f Depar t) (Member...

  14. Toxic Chemical Release Inventory reporting ``Qs & As``. Environmental Guidance

    SciTech Connect (OSTI)

    Not Available

    1994-03-01T23:59:59.000Z

    This document offers guidance on toxic chemical release inventory reporting, pursuant to Section 313 of the Emergency Planning and Community Right-to-Know Act (EPCRA) at DOE sites.

  15. Adsorbed Polymer and NOM Limits Adhesion and Toxicity of Nano

    E-Print Network [OSTI]

    Alvarez, Pedro J.

    Adsorbed Polymer and NOM Limits Adhesion and Toxicity of Nano Scale Zerovalent Iron to E. coli Z H. Here we assess the effect that adsorbed synthetic polymers and natural organic matter

  16. Electrically Heated High Temperature Incineration of Air Toxics 

    E-Print Network [OSTI]

    Agardy, F. J.; Wilcox, J. B.

    1990-01-01T23:59:59.000Z

    In-Process Technology has placed a prototype of its patented, electrically heated, packed-bed air toxics oxidizer at a northern California chemical plant. This thermal oxidizer is capable of handling a wide range of chlorinated and non...

  17. acute lethal toxicity: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 21 Review The Toxicity of Depleted Uranium CiteSeer Summary: Abstract: Depleted uranium (DU) is an emerging...

  18. acute regional toxicity: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    injection or rapid (more) Litonius, Erik 2012-01-01 34 Review The Toxicity of Depleted Uranium CiteSeer Summary: Abstract: Depleted uranium (DU) is an emerging environmental...

  19. acute skin toxicity: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    carcinogenic Hexavalent Cr(VI) is most toxic and most soluble Induces (depleted uranium) 4 oxidation states (+4, +6 most common) U(VI) water-soluble, U(IV)...

  20. acute toxicity sensitivity: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Morel; Er Complexing; Faust Steemann Nielsen 1978-01-01 37 Review The Toxicity of Depleted Uranium CiteSeer Summary: Abstract: Depleted uranium (DU) is an emerging environmental...

  1. adriamycin induced toxic: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    carcinogenic Hexavalent Cr(VI) is most toxic and most soluble Induces (depleted uranium) 4 oxidation states (+4, +6 most common) U(VI) water-soluble, U(IV)...

  2. air toxics exposure: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Top Three Toxic Air Pollutants in Oregon 0.00 2.00 4.00 6.00 8.00 10.00 12 12;Sources of Air Pollution 12;Air Pollutants Criteria Pollutants - Short list - National...

  3. Drilling fluids and reserve pit toxicity

    SciTech Connect (OSTI)

    Leuterman, A.J.J.; Jones, F.V.; Chandler, J.E. (M-I Drilling Fluids Co. (US))

    1988-11-01T23:59:59.000Z

    Drilling fluids are now classified as exempt under the Resource Conservation and Recovery Act (RCRA) hazardous waste laws. Since 1986, however, the U.S. Environmental Protection Agency (EPA) has been studying reserve pit contents to determine whether oilfield wastes should continue under this exemption. Concerns regarding reserve pit contents and disposal practices have resulted in state and local governmental regulations that limit traditional methods of construction, closure, and disposal of reserve pit sludge and water. A great deal of attention and study has been focused on drilling fluids that eventually reside in reserve pits. In-house studies show that waste from water-based drilling fluids plays a limited role (if any) in possible hazards associated with reserve pits. Reserve pit water samples and pit sludge was analyzed and collated. Analyses show that water-soluble heavy metals (Cr, Pb, Zn and Mn) in reserve pits are generally undetectable or, if found in the total analysis, are usually bound to clays or organics too tightly to exceed the limitations as determined by the EPA toxicity leachate test. The authors' experience is that most contamination associated with reserve pits involves high salt content from produced waters and/or salt formations, lead contamination from pipe dope, or poorly designed pits, which could allow washouts into surface waters or seepage into groundwater sources. The authors' analyses show that reserve its associated with water-based drilling fluid operations should not be classified as hazardous; however, careful attention attention should be paid to reserve pit construction and closure to help avoid any adverse environmental impact.

  4. Isolation and identification of a toxic metabolite of Phomopsis sp.

    E-Print Network [OSTI]

    Samples, Daniel Robert

    1982-01-01T23:59:59.000Z

    ISOLATION AND IDENTIFICATION OF A TOXIC MEl'ABOLITE OF PHOMOPSIS SP. A Thesis by DANIEL ROBERT SAMPLES Submitted to the Graduate College of' Texas A&B University in partial fulfillment of the requirement for the degree of MASTER OF SCIENCE... MAY 1982 Major Subject~ Veterinary Toxicology ISOLATION AND IDENTIFICATION OF A TOXIC METABOLITE OF PHOMOPSIS SP. A Thesis by DANIEL ROBERT SAMPLES Approved as to style and content by: (Chairman of Committee) (Membe (Mem ) (Head of Departme t...

  5. The recognition of toxic contaminants in sea water by bioassay

    E-Print Network [OSTI]

    Duke, Thomas Wade

    1960-01-01T23:59:59.000Z

    THE RECOGNITION OF TOXIC CONTAMINANTS IN SEA WATER BY BIOASSAY A Thesis By THOMAS WADE DUKE Submitted to the Graduate School of the Agricultural and Mechanical College of Texas in partial fulfillment of the requirements for the degree... of MASTER OF SCIENCE January 1960 Major Subject: Biological Oceanography THE RECOGNITION OF TOXIC CONTAMINANTS IN SEA li'ATER BY BIOASSAY A Thesis THOMAS O'ADE DUKE Approved as to style and content by: ( airman o emmy ee wi, ( ea of Depar me...

  6. Evaluating guayule resin fractions for mutagenicity and toxicity

    E-Print Network [OSTI]

    Avirett, Donald Baker

    1992-01-01T23:59:59.000Z

    EVALUATING GUAYULE RESIN FRACTIONS FOR NUTAGENICITY AND TOXICITY A Thesis by DONALD BAKER AVIRETT Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements for the degree of MASTER... OF SCIENCE December 1992 Major Subject: Industrial Hygiene EVALUATING GUAYULE RESIN FRACTIONS FOR MUTAGENICITY AND TOXICITY A Thesis by DONALD BAKER AVIRETT Submitted to Texas A&M University in partial fulfillment of the requirements for the degree...

  7. The recognition of toxic contaminants in sea water by bioassay 

    E-Print Network [OSTI]

    Duke, Thomas Wade

    1960-01-01T23:59:59.000Z

    THE RECOGNITION OF TOXIC CONTAMINANTS IN SEA WATER BY BIOASSAY A Thesis By THOMAS WADE DUKE Submitted to the Graduate School of the Agricultural and Mechanical College of Texas in partial fulfillment of the requirements for the degree... of MASTER OF SCIENCE January 1960 Major Subject: Biological Oceanography THE RECOGNITION OF TOXIC CONTAMINANTS IN SEA li'ATER BY BIOASSAY A Thesis THOMAS O'ADE DUKE Approved as to style and content by: ( airman o emmy ee wi, ( ea of Depar me...

  8. A golden opportunity: Researchers making progress in understanding toxic algae 

    E-Print Network [OSTI]

    Wythe, Kathy

    2008-01-01T23:59:59.000Z

    Researchers making progress in understanding toxic algae A golden opportunity tx H2O | pg. 21 have examined the organism in coastal, saline environments. ?Our research team represents one of the few in the world that is focused on the dynamics... throughout Texas. Although it can exist in waters without being harmful, the algae has caused major fish kills in five of the state?s river systems. When this algae has explosive increases in its population, called ?blooms,? it secretes toxic chemicals...

  9. Isolation and identification of a toxic metabolite of Phomopsis sp. 

    E-Print Network [OSTI]

    Samples, Daniel Robert

    1982-01-01T23:59:59.000Z

    ISOLATION AND IDENTIFICATION OF A TOXIC MEl'ABOLITE OF PHOMOPSIS SP. A Thesis by DANIEL ROBERT SAMPLES Submitted to the Graduate College of' Texas A&B University in partial fulfillment of the requirement for the degree of MASTER OF SCIENCE... MAY 1982 Major Subject~ Veterinary Toxicology ISOLATION AND IDENTIFICATION OF A TOXIC METABOLITE OF PHOMOPSIS SP. A Thesis by DANIEL ROBERT SAMPLES Approved as to style and content by: (Chairman of Committee) (Membe (Mem ) (Head of Departme t...

  10. Toxic and deadly: Working to manage algae in Lake Granbury 

    E-Print Network [OSTI]

    Wythe, Kathy

    2010-01-01T23:59:59.000Z

    Toxic and deadly Working to manage algae in Lake Granbury Lake Granbury, located about 33 miles southwest of Fort Worth, is a recreation haven for water enthusiasts. In recent years, however, bacteria and golden algae have threatened the lake... of water and the presence of pathogens. These E. coli sources can be from sewage overflows, polluted stormwater runoff, or malfunctioning septic systems. Toxic golden algae blooms have killed fish in Lake Granbury and Lake Whitney, downstream...

  11. Toxic and deadly: Working to manage algae in Lake Granbury 

    E-Print Network [OSTI]

    Wythe, Kathy

    2011-01-01T23:59:59.000Z

    Toxic and deadly Working to manage algae in Lake Granbury Lake Granbury, located about 33 miles southwest of Fort Worth, is a recreation haven for water enthusiasts. In recent years, however, bacteria and golden algae have threatened the lake... of water and the presence of pathogens. These E. coli sources can be from sewage overflows, polluted stormwater runoff, or malfunctioning septic systems. Toxic golden algae blooms have killed fish in Lake Granbury and Lake Whitney, downstream...

  12. r e v i e w OrganicAnswers toToxic Questions

    E-Print Network [OSTI]

    disasters--gasoline leaking into groundwater from under- ground storage tanks or toxic chemicals from

  13. Exploring Cyberbullying and Other Toxic Behavior in Team Competition Online Games

    E-Print Network [OSTI]

    Kwak, Haewoon; Han, Seungyeop

    2015-01-01T23:59:59.000Z

    In this work we explore cyberbullying and other toxic behavior in team competition online games. Using a dataset of over 10 million player reports on 1.46 million toxic players along with corresponding crowdsourced decisions, we test several hypotheses drawn from theories explaining toxic behavior. Besides providing large-scale, empirical based understanding of toxic behavior, our work can be used as a basis for building systems to detect, prevent, and counter-act toxic behavior.

  14. Oxidation reactions of solid carbonaceous and resinous substances in supercritical water

    SciTech Connect (OSTI)

    Koda, S. [Sophia University, Tokyo (Japan). Dept. of Material and Life Science

    2009-01-15T23:59:59.000Z

    Recent kinetic studies, particularly those by means of shadowgraphy and X-ray radiography, for supercritical water oxidation of solid carbonaceous and resinous substances have revealed the importance of the O{sub 2} mass transfer process over the intrinsic surface reaction at higher temperatures. The mass transfer processes, internal and external one, should be incorporated in designing SCWO processes for solid substances and related processes such as catalytic SCWO. Some model calculation efforts of late are briefly described. Finally, fundamental information required for future development is itemed.

  15. REGULATORY STRATEGIES TO MINIMIZE GENERATION OF REGULATED WASTES FROM CLEANUP, CONTINUED USE OR DECOMMISSIONING OF NUCLEAR FACILITIES CONTAMINATED WITH POLYCHLORINATED BIPHENYLS (PCBS) - 11198

    SciTech Connect (OSTI)

    Lowry, N.

    2010-11-05T23:59:59.000Z

    Disposal costs for liquid PCB radioactive waste are among the highest of any category of regulated waste. The high cost is driven by the fact that disposal options are extremely limited. Toxic Substances Control Act (TSCA) regulations require most liquids with PCBs at concentration of {ge} 50 parts-per-million to be disposed by incineration or equivalent destructive treatment. Disposal fees can be as high as $200 per gallon. This figure does not include packaging and the cost to transport the waste to the disposal facility, or the waste generator's labor costs for managing the waste prior to shipment. Minimizing the generation of liquid radioactive PCB waste is therefore a significant waste management challenge. PCB spill cleanups often generate large volumes of waste. That is because the removal of PCBs typically requires the liberal use of industrial solvents followed by a thorough rinsing process. In a nuclear facility, the cleanup process may be complicated by the presence of radiation and other occupational hazards. Building design and construction features, e.g., the presence of open grating or trenches, may also complicate cleanup. In addition to the technical challenges associated with spill cleanup, selection of the appropriate regulatory requirements and approach may be challenging. The TSCA regulations include three different sections relating to the cleanup of PCB contamination or spills. EPA has also promulgated a separate guidance policy for fresh PCB spills that is published as Subpart G of 40 CFR 761 although it is not an actual regulation. Applicability is based on the circumstances of each contamination event or situation. Other laws or regulations may also apply. Identification of the allowable regulatory options is important. Effective communication with stakeholders, particularly regulators, is just as important. Depending on the regulatory path that is taken, cleanup may necessitate the generation of large quantities of regulated waste. Allowable options must be evaluated carefully in order to reduce compliance risks, protect personnel, limit potential negative impacts on facility operations, and minimize the generation of wastes subject to TSCA. This paper will identify critical factors in selecting the appropriate TSCA regulatory path in order to minimize the generation of radioactive PCB waste and reduce negative impacts to facilities. The importance of communicating pertinent technical issues with facility staff, regulatory personnel, and subsequently, the public, will be discussed. Key points will be illustrated by examples from five former production reactors at the DOE Savannah River Site. In these reactors a polyurethane sealant was used to seal piping penetrations in the biological shield walls. During the intense neutron bombardment that occurred during reactor operation, the sealant broke down into a thick, viscous material that seeped out of the piping penetrations over adjacent equipment and walls. Some of the walls were painted with a PCB product. PCBs from the paint migrated into the degraded sealant, creating PCB 'spill areas' in some of these facilities. The regulatory cleanup approach selected for each facility was based on its operational status, e.g., active, inactive or undergoing decommissioning. The selected strategies served to greatly minimize the generation of radioactive liquid PCB waste. It is expected that this information would be useful to other DOE sites, DOD facilities, and commercial nuclear facilities constructed prior to the 1979 TSCA ban on most manufacturing and uses of PCBs.

  16. Hypolimnetic oxygen consumption by sediment-based reduced substances in former eutrophic lakes

    E-Print Network [OSTI]

    Wehrli, Bernhard

    Hypolimnetic oxygen consumption by sediment-based reduced substances in former eutrophic lakes) in two formerly eutrophic lakes based on 20 yr of water-column data collected during oligotrophication, including the eutrophic past, accounted for , 15% of AHM. This ``old'' contribution corresponds to a 20

  17. Is it possible to observe a suppressing of $?$-decay caused by an atomic substance - plasma transition ?

    E-Print Network [OSTI]

    B. V. Vasiliev

    2006-04-24T23:59:59.000Z

    It is supposed that $\\beta$-decay can be slightly suppressed at an atomic substance - plasma transition under a plasma electron gas action. The estimation shows that this effect can give a relative difference of the decay amount on a level of $10^{-4}$.

  18. The evaluation of an analytical protocol for the determination of substances in waste for hazard classification

    E-Print Network [OSTI]

    Boyer, Edmond

    1 The evaluation of an analytical protocol for the determination of substances in waste for hazard The classification of waste as hazardous could soon be assessed in Europe using largely the hazard properties of its knowledge of the component constituents of a given waste will therefore be necessary. An analytical protocol

  19. In 2005 The Substance Abuse and Mental Health Services Administration (SAMHSA) convened a national summit on

    E-Print Network [OSTI]

    Polly, David

    , wellness and quality of life." #12;Treatment Prevention Clinical Care Social Work Counseling Family's own resources to overcome addiction, most common form of recovery , most viable for those who have less severe substance use or gambling problems Treatment-individuals with chronic dependence who

  20. UMBC SUBSTANCE ABUSE POLICY* UMBC Policy # III-5.00.04

    E-Print Network [OSTI]

    Adali, Tulay

    of this policy may be subject to corrective action under applicable University Human Resources policies individuals are subject to University disciplinary processes and/or arrest and criminal prosecution. Federal to manufacture, distribute or dispense a controlled substance, especially if done so near a public or private

  1. San Francisco Estuary Regional Monitoring Program for Trace Substances Estimates of Suspended-sediment Flux

    E-Print Network [OSTI]

    interpolation. A model was developed to estimate fluxes associated with tidal advection and dispersion using. On an annual basis, dispersive flux caused an upstream sediment flux of about 0.39 Mt (million metric tonnesSan Francisco Estuary Regional Monitoring Program for Trace Substances Estimates of Suspended-sediment

  2. Searching for Inorganic Substances using the Molecular Formula Search Field The following inorganic compounds can be searched within Reaxys

    E-Print Network [OSTI]

    Searching for Inorganic Substances using the Molecular Formula Search Field The following inorganic, but the exercise deals with the molecular formula search field. #12;Scenario: Search for Reactions containing on the [+] sign for Substance identification Click on the Molecular formula field. Leave the "is" operator

  3. Intelligent emissions controller for substance injection in the post-primary combustion zone of fossil-fired boilers

    DOE Patents [OSTI]

    Reifman, Jaques (Western Springs, IL); Feldman, Earl E. (Willowbrook, IL); Wei, Thomas Y. C. (Downers Grove, IL); Glickert, Roger W. (Pittsburgh, PA)

    2003-01-01T23:59:59.000Z

    The control of emissions from fossil-fired boilers wherein an injection of substances above the primary combustion zone employs multi-layer feedforward artificial neural networks for modeling static nonlinear relationships between the distribution of injected substances into the upper region of the furnace and the emissions exiting the furnace. Multivariable nonlinear constrained optimization algorithms use the mathematical expressions from the artificial neural networks to provide the optimal substance distribution that minimizes emission levels for a given total substance injection rate. Based upon the optimal operating conditions from the optimization algorithms, the incremental substance cost per unit of emissions reduction, and the open-market price per unit of emissions reduction, the intelligent emissions controller allows for the determination of whether it is more cost-effective to achieve additional increments in emission reduction through the injection of additional substance or through the purchase of emission credits on the open market. This is of particular interest to fossil-fired electrical power plant operators. The intelligent emission controller is particularly adapted for determining the economical control of such pollutants as oxides of nitrogen (NO.sub.x) and carbon monoxide (CO) emitted by fossil-fired boilers by the selective introduction of multiple inputs of substances (such as natural gas, ammonia, oil, water-oil emulsion, coal-water slurry and/or urea, and combinations of these substances) above the primary combustion zone of fossil-fired boilers.

  4. Disposal requirements for PCB waste

    SciTech Connect (OSTI)

    NONE

    1994-12-01T23:59:59.000Z

    Polychlorinated biphenyls (PCBs) are a class of organic chemicals that had become widely used in industrial applications due to their practical physical and chemical properties. Historical uses of PCBs include dielectric fluids (used in utility transformers, capacitors, etc.), hydraulic fluids, and other applications requiring stable, fire-retardant materials. Due to findings that PCBs may cause adverse health effects and due to their persistence and accumulation in the environment, the Toxic Substances Control Act (TSCA), enacted on october 11, 1976, banned the manufacture of PCBs after 1978 [Section 6(e)]. The first PCB regulations, promulgated at 40 CFR Part 761, were finalized on February 17, 1978. These PCB regulations include requirements specifying disposal methods and marking (labeling) procedures, and controlling PCB use. To assist the Department of Energy (DOE) in its efforts to comply with the TSCA statute and implementing regulations, the Office of Environmental Guidance has prepared the document ``Guidance on the Management of Polychlorinated Biphenyls (PCBs).`` That document explains the requirements specified in the statute and regulations for managing PCBs including PCB use, storage, transport, and disposal. PCB materials that are no longer in use and have been declared a waste must be disposed of according to the requirements found at 40 CFR 761.60. These requirements establish disposal options for a multitude of PCB materials including soil and debris, liquid PCBs, sludges and slurries, containers, transformers, capacitors, hydraulic machines, and other electrical equipment. This Information Brief supplements the PCB guidance document by responding to common questions concerning disposal requirements for PCBs. It is one of a series of Information Briefs pertinent to PCB management issues.

  5. Energy efficiency of substance and energy recovery of selected waste fractions

    SciTech Connect (OSTI)

    Fricke, Klaus, E-mail: klaus.fricke@tu-bs.de [Technical University of Braunschweig, Leichtweiss-Institute, Department of Waste and Resource Management, Beethovenstrasse 51a, 38106 Braunschweig (Germany); Bahr, Tobias, E-mail: t.bahr@tu-bs.de [Technical University of Braunschweig, Leichtweiss-Institute, Department of Waste and Resource Management, Beethovenstrasse 51a, 38106 Braunschweig (Germany); Bidlingmaier, Werner, E-mail: werner.bidlingmaier@uni-weimar.de [Bauhaus-Universitaet Weimar, Faculty of Civil Engineering, Waste Management, Coudraystrasse 7, 99423 Weimar (Germany); Springer, Christian, E-mail: christian.springer@uni-weimar.de [Bauhaus-Universitaet Weimar, Faculty of Civil Engineering, Waste Management, Coudraystrasse 7, 99423 Weimar (Germany)

    2011-04-15T23:59:59.000Z

    In order to reduce the ecological impact of resource exploitation, the EU calls for sustainable options to increase the efficiency and productivity of the utilization of natural resources. This target can only be achieved by considering resource recovery from waste comprehensively. However, waste management measures have to be investigated critically and all aspects of substance-related recycling and energy recovery have to be carefully balanced. This article compares recovery methods for selected waste fractions with regard to their energy efficiency. Whether material recycling or energy recovery is the most energy efficient solution, is a question of particular relevance with regard to the following waste fractions: paper and cardboard, plastics and biowaste and also indirectly metals. For the described material categories material recycling has advantages compared to energy recovery. In accordance with the improved energy efficiency of substance opposed to energy recovery, substance-related recycling causes lower emissions of green house gases. For the fractions paper and cardboard, plastics, biowaste and metals it becomes apparent, that intensification of the separate collection systems in combination with a more intensive use of sorting technologies can increase the extent of material recycling. Collection and sorting systems must be coordinated. The objective of the overall system must be to achieve an optimum of the highest possible recovery rates in combination with a high quality of recyclables. The energy efficiency of substance related recycling of biowaste can be increased by intensifying the use of anaerobic technologies. In order to increase the energy efficiency of the overall system, the energy efficiencies of energy recovery plants must be increased so that the waste unsuitable for substance recycling is recycled or treated with the highest possible energy yield.

  6. Review article Aluminium toxicity in plants: a review

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Review article Aluminium toxicity in plants: a review G.R. ROUTa, S. SAMANTARAYb, P. DASb* a Plant Biotechnology Division, Regional Plant Resource Centre, Bhubaneswar- 751 015, Orissa, India b Plant Physiology and Biochemistry Laboratory, Regional Plant Resource Centre, Bhubaneswar- 751 015, Orissa, India (Received 31 May

  7. In vivo toxicity studies of europium hydroxide nanorods in mice

    SciTech Connect (OSTI)

    Patra, Chitta Ranjan [Department of Biochemistry and Molecular Biology, 200 First Street S.W, Guggenheim 1321A, Mayo Clinic College of Medicine, Mayo Foundation, Rochester, MN 55905 (United States)], E-mail: patra.chittaranjan@mayo.edu; Abdel Moneim, Soha S. [Gastroenterology and Hepatology, GI Research Unit, 200 First Street S.W, Guggenheim 1034, Mayo Clinic College of Medicine, Mayo Foundation, Rochester, MN 55905 (United States); Wang, Enfeng; Dutta, Shamit; Patra, Sujata [Department of Biochemistry and Molecular Biology, 200 First Street S.W, Guggenheim 1321A, Mayo Clinic College of Medicine, Mayo Foundation, Rochester, MN 55905 (United States); Eshed, Michal [Department of Chemistry and Kanbar Laboratory for Nanomaterials, Bar-Ilan University Center for Advanced Materials and Nanotechnology, Bar-Ilan University, Ramat-Gan 52900 (Israel); Mukherjee, Priyabrata [Department of Biochemistry and Molecular Biology, 200 First Street S.W, Guggenheim 1321A, Mayo Clinic College of Medicine, Mayo Foundation, Rochester, MN 55905 (United States); Department of Biomedical Engineering, 200 First Street S.W, Guggenheim 1334, Mayo Clinic College of Medicine, Mayo Foundation, Rochester, MN 55905 (United States); Gedanken, Aharon [Department of Chemistry and Kanbar Laboratory for Nanomaterials, Bar-Ilan University Center for Advanced Materials and Nanotechnology, Bar-Ilan University, Ramat-Gan 52900 (Israel); Shah, Vijay H. [Gastroenterology and Hepatology, GI Research Unit, 200 First Street S.W, Guggenheim 1034, Mayo Clinic College of Medicine, Mayo Foundation, Rochester, MN 55905 (United States); Mukhopadhyay, Debabrata [Department of Biochemistry and Molecular Biology, 200 First Street S.W, Guggenheim 1321A, Mayo Clinic College of Medicine, Mayo Foundation, Rochester, MN 55905 (United States); Department of Biomedical Engineering, 200 First Street S.W, Guggenheim 1334, Mayo Clinic College of Medicine, Mayo Foundation, Rochester, MN 55905 (United States)

    2009-10-01T23:59:59.000Z

    Lanthanide nanoparticles and nanorods have been widely used for diagnostic and therapeutic applications in biomedical nanotechnology due to their fluorescence and pro-angiogenic properties to endothelial cells, respectively. Recently, we have demonstrated that europium (III) hydroxide [Eu{sup III}(OH){sub 3}] nanorods, synthesized by the microwave technique and characterized by several physico-chemical techniques, can be used as pro-angiogenic agents which introduce future therapeutic treatment strategies for severe ischemic heart/limb disease, and peripheral ischemic disease. The toxicity of these inorganic nanorods to endothelial cells was supported by several in vitro assays. To determine the in vivo toxicity, these nanorods were administered to mice through intraperitoneal injection (IP) everyday over a period of seven days in a dose dependent (1.25 to 125 mg kg{sup -1} day{sup -1}) and time dependent manner (8-60 days). Bio-distribution of europium elements in different organs was analyzed by inductively coupled plasma mass spectrometry (ICPMS). Short-term (S-T) and long-term (L-T) toxicity studies (mice euthanized on days 8 and 60 for S-T and L-T, respectively) show normal blood hematology and serum clinical chemistry with the exception of a slight elevation of liver enzymes. Histological examination of nanorod-treated vital organs (liver, kidney, spleen and lungs) showed no or only mild histological changes that indicate mild toxicity at the higher dose of nanorods.

  8. Acute toxicity of organic solvents on Artemia salina

    SciTech Connect (OSTI)

    Barahona-Gomariz, M.V.; Sanz-Barrera, F.; Sanchez-Fortun, S. (Complutense Univ. of Madrid (Spain))

    1994-05-01T23:59:59.000Z

    Organic solvents can make their way into the environment as industrial wastes and components of pesticide formulation. In laboratory bioassays, the use of organic formulations. In laboratory bioassays, the use of organic solvents is often unavoidable, since many pesticides and organic pollutants have low water solubility and must be dissolved in organic solvents prior to addition into experimental systems. In the toxicant bioassays, invertebrates with special reference to aquatic arthropod species are of recent interest as test models due to the need for developing nonmammalian test systems. Toxic effects of organic solvents have been tested with a few aquatic species, but information on the comparative toxicity of solvents towards Artemia salina is not available. Artemia salina have, within recent years, gained popularity as test organisms for short-term toxicity testing. Because Artemia salina exhibit rapid development and growth within 48 hr after hatch, their potential as a model organism for toxicology screening has been considered. To do this, synchronous populations of Artemia salina at different development intervals must be available.

  9. Tolerance of nitrobacter to toxicity of some Nigerian crude oils

    SciTech Connect (OSTI)

    Okpokwasili, G.C.; Odokuma, L.O. (Univ. of Port Harcourt (Nigeria))

    1994-03-01T23:59:59.000Z

    Crude oil spillage in aquatic systems affects thousands of aquatic species including bacteria. Some of the crude oil components are rapidly evaporated or biologically degraded. Other components continue to remain for several months and perhaps several years. Some of these components may be toxic to microorganisms, while some may stimulate microbial activity especially at low concentrations. The use of bacteria as bioassay organisms is now gaining wide acceptance. It offers a number of advantages such as ease of handling, economy of space, short life cycles and low cost. Their uses in bioassays are based on cell lysis, mutagenic properties and the inhibition of physiological processes such as respiration. Recently, a number of workers have proposed the use of Nitrobacter as a test organism. The organism has a number of advantages in toxicity testing: obligate autotrophy, its sensitivity to various toxicants and its predominance in wastewater environments are some of them . Of recent, the inhibition of bacterial enzyme biosynthesis have been suggested in bacterial assays. The objective of this study was to determine the effects of six Nigerian crude oils on the cell reproduction rate (LC, lethal concentration), cellular respiration (EC, effective concentration) and biosynthesis of enzyme responsible for nitrite oxidation (IC, inhibition concentration) in Nitrobacter. In addition, the goal was to identify which of these was the most sensitive to crude oil and which may thus be used for detecting the toxicity of these chemicals. 18 refs., 2 figs., 1 tab.

  10. Acute and Genetic Toxicity of Municipal Landfill Leachate

    E-Print Network [OSTI]

    Brown, K.W.; Schrab, G.E.; Donnelly, K.C.

    to be representative of landfills of differing ages and types of wastes. Each sample was tested through three genetic toxicity bioassays (The Aspergillus diploid assay, the Bacillus DNA repair assay and the Salmonella/microsome assay) to measure the ability of each...

  11. Acute and Genetic Toxicity of Municipal Landfill Leachate 

    E-Print Network [OSTI]

    Brown, K.W.; Schrab, G.E.; Donnelly, K.C.

    1991-01-01T23:59:59.000Z

    to be representative of landfills of differing ages and types of wastes. Each sample was tested through three genetic toxicity bioassays (The Aspergillus diploid assay, the Bacillus DNA repair assay and the Salmonella/microsome assay) to measure the ability of each...

  12. Survey of toxicity and carcinogenity of mineral deposits

    SciTech Connect (OSTI)

    Furst, A.; Harding-Barlow, I.

    1981-11-03T23:59:59.000Z

    The toxicities and biogeochemical cycles of arsenic, cadmium, chromium, lead and nickel are reviewed in some detail, and other trace elements briefly mentioned. These heavy metals are used as a framework within which the problem of low-level radioactive waste disposal can be compared. (ACR)

  13. Toxicity evaluation and hazard review for Rigid Foam

    SciTech Connect (OSTI)

    Archuleta, M.M.; Stocum, W.E.

    1994-02-01T23:59:59.000Z

    Rigid Foam is a chemical delay foam used to completely encapsulate an object or to block access to an area. Prior studies have indicated that the final foam product is essentially non-toxic. The purpose of this study was to evaluate and summarize the current chemical and toxicological data available on the components of Rigid Foam and to update the information available on the toxicity of the final Rigid Foam product. Since the possibility exists for a partial deployment of Rigid Foam where only one of the components is released, this study also examined the toxicity of its chemical constituents. Rigid Foam is composed of an {open_quotes}A{close_quotes} and {open_quotes}B{close_quotes} Component. The {open_quotes}A{close_quotes} component is primarily a polymeric isocyanate and the {open_quotes}B{close_quotes} component is a mixture of polyols. In addition to the primary constituents, dichlorodifluoromethane and trichlorofluoromethane are present as blowing agents along with catalysts and silicone surfactants necessary for foaming. The pre-deployed {open_quotes}A{close_quotes} and {open_quotes}B{close_quotes} components are stored in separate vessels and are brought together in static mixing nozzles for dispersal. The results of this evaluation indicate that a completely deployed Rigid Foam under normal conditions is essentially non-toxic as determined previously. However, in the event of a partial deployment or deployment of an individual component directly at an unprotected individual, the degree of hazard is increased due to the toxic and corrosive nature of the individual constituents. The health hazard would depend on the properties of the material to which the person was exposed.

  14. A study of toxic emissions from a coal-fired power plant utilizing an ESP while demonstrating the ICCT CT-121 FGD Project. Final report

    SciTech Connect (OSTI)

    Not Available

    1994-06-16T23:59:59.000Z

    The US Department of Energy is performing comprehensive assessments of toxic emissions from eight selected coal-fired electric utility units. This program responds to the Clean Air Act Amendments of 1990, which require the US Environmental Protection Agency (EPA) to evaluate emissions of hazardous air pollutants (HAPs) from electric utility power plants for Potential health risks. The resulting data will be furnished to EPA utility power plants and health risk determinations. The assessment of emissions involves the collection and analysis of samples from the major input, process, and output streams of each of the eight power plants for selected hazardous Pollutants identified in Title III of the Clean Air Act. Additional goals are to determine the removal efficiencies of pollution control subsystems for these selected pollutants and the Concentrations associated with the particulate fraction of the flue gas stream as a function of particle size. Material balances are being performed for selected pollutants around the entire power plant and several subsystems to identify the fate of hazardous substances in each utility system. Radian Corporation was selected to perform a toxics assessment at a plant demonstrating an Innovative Clean Coal Technology (ICCT) Project. The site selected is Plant Yates Unit No. 1 of Georgia Power Company, which includes a Chiyoda Thoroughbred-121 demonstration project.

  15. Comparison of three marine screening tests and four Oslo and Paris Commission procedures to evaluate toxicity of offshore chemicals

    SciTech Connect (OSTI)

    Weideborg, M.; Vik, E.A.; Oefjord, G.D.; Kjoennoe, O. [Aquateam-Norwegian Water Technology Centre A/S, Oslo (Norway)

    1997-02-01T23:59:59.000Z

    The results from the screening toxicity tests Artemia salina, Microtox{reg_sign}, and Mitochondria RET test were compared with those obtained from OSPAR (Oslo and Paris Commissions)-authorized procedures for testing of offshore chemicals (Skeletonema costatum, Acartia tonsa, Abra alba, and Corophium volutator). In this study 82 test substances (26 non-water soluble) were included. The Microtox test was found to be the most sensitive of the three screening tests. Microtox and Mitochondria RET test results showed good correlation with results from Acartia and Skeletonema testing, and it was concluded that the Microtox test was a suitable screening test as a base for assessment of further testing, especially regarding water-soluble chemicals. Sensitivity of Artemia salina to the tested chemicals was too low for it to be an appropriate bioassay organism for screening testing. A very good correlation was found between the results obtained with the Skeletonema and Acartia tests. The results indicated no need for more than one of the Skeletonema or Acartia tests if the Skeletonema median effective concentration or Acartia median lethal concentration was greater than 200 mg/L. The sediment-reworker tests (A. Alba or C. volutator) for chemicals that are likely to end up in the sediments (non-water soluble or surfactants) should be performed, independent of results from screening tests and other OSPAR species.

  16. A mechanism for diversity in warning signals: Conspicuousness versus toxicity in poison frogs

    E-Print Network [OSTI]

    Cummings, Molly E.

    A mechanism for diversity in warning signals: Conspicuousness versus toxicity in poison frogs natural variation among poison frog species measured with spectral reflectance and toxicity assays, we components using natural variation among poison frog species. Poison frogs (Dendrobatidae) display some

  17. Integrated Toxic Plant Management Handbook: Livestock Poisoning Plants of the Trans-Pecos Region of Texas

    E-Print Network [OSTI]

    Hart, Charles R.; McGinty, Allan; Carpenter, Bruce B.

    2001-01-11T23:59:59.000Z

    Photographs, plant descriptions, and symptoms of poisoning help ranchers identify toxic plants that may be harmful to their livestock in West Texas. There is also information on grazing, livestock management, and toxic plant control....

  18. Integrated Toxic Plant Management Handbook: Livestock Poisoning Plants of the Trans-Pecos Region of Texas 

    E-Print Network [OSTI]

    Hart, Charles R.; McGinty, Allan; Carpenter, Bruce B.

    2001-01-11T23:59:59.000Z

    Photographs, plant descriptions, and symptoms of poisoning help ranchers identify toxic plants that may be harmful to their livestock in West Texas. There is also information on grazing, livestock management, and toxic plant control....

  19. Toxicity of oiled wetland sediments influenced by natural and enhanced bioremediation 

    E-Print Network [OSTI]

    Mueller, Danica Christine

    1998-01-01T23:59:59.000Z

    were set aside for petroleum bioremediation studies. Phase I began in December of 1994 and monitored sediment toxicity associated with intrinsic petroleum degradation. Acute toxicity was evaluated using the Microtox 100% Test on sediment elutriates from...

  20. Captain Planet Takes on Hazard Transfer: Combining the Forces of Market, Legal and Ethical Decisionmaking to Reduce Toxic Exports

    E-Print Network [OSTI]

    Giampetro-Meyer, Andrea

    2009-01-01T23:59:59.000Z

    infra Part II; see generally Toxic EXPORTS, supra note 5.82. Toxic EXPORTS, supra note 5. See infra Part II. 83.of California). 31. Toxic EXPORTS, supra note 5, at 9. Clapp

  1. Reliability of Quantitative Ultrasonic Assessment of Normal-Tissue Toxicity in Breast Cancer Radiotherapy

    SciTech Connect (OSTI)

    Yoshida, Emi J.; Chen Hao [Department of Radiation Oncology, Emory University, Atlanta, GA (United States); Torres, Mylin [Department of Radiation Oncology, Emory University, Atlanta, GA (United States); Winship Cancer Institute, Emory University, Atlanta, GA (United States); Andic, Fundagul [Winship Cancer Institute, Emory University, Atlanta, GA (United States); Liu Haoyang [Department of Radiation Oncology, Emory University, Atlanta, GA (United States); Chen Zhengjia [Winship Cancer Institute, Emory University, Atlanta, GA (United States); Department of Statistics, Emory University, Atlanta, GA (United States); Sun, Xiaoyan [Department of Statistics, Emory University, Atlanta, GA (United States); Curran, Walter J. [Department of Radiation Oncology, Emory University, Atlanta, GA (United States); Winship Cancer Institute, Emory University, Atlanta, GA (United States); Liu Tian, E-mail: tliu34@emory.edu [Department of Radiation Oncology, Emory University, Atlanta, GA (United States); Winship Cancer Institute, Emory University, Atlanta, GA (United States)

    2012-02-01T23:59:59.000Z

    Purpose: We have recently reported that ultrasound imaging, together with ultrasound tissue characterization (UTC), can provide quantitative assessment of radiation-induced normal-tissue toxicity. This study's purpose is to evaluate the reliability of our quantitative ultrasound technology in assessing acute and late normal-tissue toxicity in breast cancer radiotherapy. Method and Materials: Our ultrasound technique analyzes radiofrequency echo signals and provides quantitative measures of dermal, hypodermal, and glandular tissue toxicities. To facilitate easy clinical implementation, we further refined this technique by developing a semiautomatic ultrasound-based toxicity assessment tool (UBTAT). Seventy-two ultrasound studies of 26 patients (720 images) were analyzed. Images of 8 patients were evaluated for acute toxicity (<6 months postradiotherapy) and those of 18 patients were evaluated for late toxicity ({>=}6 months postradiotherapy). All patients were treated according to a standard radiotherapy protocol. To assess intraobserver reliability, one observer analyzed 720 images in UBTAT and then repeated the analysis 3 months later. To assess interobserver reliability, three observers (two radiation oncologists and one ultrasound expert) each analyzed 720 images in UBTAT. An intraclass correlation coefficient (ICC) was used to evaluate intra- and interobserver reliability. Ultrasound assessment and clinical evaluation were also compared. Results: Intraobserver ICC was 0.89 for dermal toxicity, 0.74 for hypodermal toxicity, and 0.96 for glandular tissue toxicity. Interobserver ICC was 0.78 for dermal toxicity, 0.74 for hypodermal toxicity, and 0.94 for glandular tissue toxicity. Statistical analysis found significant changes in dermal (p < 0.0001), hypodermal (p = 0.0027), and glandular tissue (p < 0.0001) assessments in the acute toxicity group. Ultrasound measurements correlated with clinical Radiation Therapy Oncology Group (RTOG) toxicity scores of patients in the late toxicity group. Patients with RTOG Grade 1 or 2 had greater ultrasound-assessed toxicity percentage changes than patients with RTOG Grade 0. Conclusion: Early and late radiation-induced effects on normal tissue can be reliably assessed using quantitative ultrasound.

  2. Dose Dependent Response to Cyclodextrin Infusion in a Rat Model of Verapamil Toxicity

    E-Print Network [OSTI]

    Mottram, Allan R.; Bryant, Sean M; Aks, Steven E

    2012-01-01T23:59:59.000Z

    Model of Verapamil Toxicity Allan R. Mottram, MD* Sean M.Address for Correspondence: Allan R. Mottram, MD, University

  3. System and method for identifying, reporting, and evaluating presence of substance

    DOE Patents [OSTI]

    Smith, Maurice (Kansas City, MO); Lusby, Michael (Kansas City, MO); Van Hook, Arthur (Lake Lotawana, MO); Cook, Charles J. (Raytown, MO); Wenski, Edward G. (Lenexa, KS); Solyom, David (Overland Park, KS)

    2006-10-24T23:59:59.000Z

    A system and method for identifying, reporting, and evaluating a presence of a solid, liquid, gas, or other substance of interest, particularly a dangerous, hazardous, or otherwise threatening chemical, biological, or radioactive substance. The system comprises one or more substantially automated, location self-aware remote sensing units; a control unit; and one or more data processing and storage servers. Data is collected by the remote sensing units and transmitted to the control unit; the control unit generates and uploads a report incorporating the data to the servers; and thereafter the report is available for review by a hierarchy of responsive and evaluative authorities via a wide area network. The evaluative authorities include a group of relevant experts who may be widely or even globally distributed.

  4. Production of multiply charged ion beams from solid substances with the mVINIS ion source

    SciTech Connect (OSTI)

    Draganic, I.; Dobrosavljevic, A.; Nedeljkovic, T.; Siljegovic, M. [Laboratory of Physics, Vinca Institute of Nuclear Sciences, P.O. Box. 522, 11000 Belgrade (Serbia and Montenegro)

    2006-03-15T23:59:59.000Z

    The mVINIS ion source has enabled us to obtain multiply charged ion beams from gases as well as from solid materials. The solid substance ion beams were produced by using two techniques: (a) the evaporation of metals by using the inlet system based on a minioven and (b) the metal-ions-from-volatile-compounds method (MIVOC) by using the modified gas inlet system. Great efforts were made in the production of high current stable ion beams of solids with relatively high melting points (over 1000 deg. C). The B{sup 3+} ion-beam current of over 300 {mu}A was one of the most intensive beams extracted until now. The obtained multiply charged ion-beam spectra of solid substances (B, Fe, and Zn) are presented as well as some of the corresponding experimental results achieved during the modification of polymers, carbon materials, and fullerenes.

  5. Nuclear data needs and sensitivities for illicit substance detection using fast-neutron transmission spectroscopy

    SciTech Connect (OSTI)

    Micklich, B.J.; Harper, M.K.; Sagalovsky, L.; Smith, D.L.

    1994-05-01T23:59:59.000Z

    Results from analysis of fast-neutron transmission spectra in the interrogation of luggage for illicit substances are quite sensitive to the neutron total cross section data employed. Monte Carlo and analytical techniques are used to explore the uses for such data and to demonstrate the sensitivity of these results to various total cross sections employed in the analysis. The status of total cross section information required for materials commonly found in containers having both illicit and benign substances, with particular attention to the matter of data uncertainties, is considered in the context of the available nuclear data. Deficiencies in the contemporary nuclear data base for this application are indicated and suggestions are offered for new measurements or evaluations.

  6. System and method for identifying, reporting, and evaluating presence of substance

    SciTech Connect (OSTI)

    Smith, Maurice (Kansas City, MO); Lusby, Michael (Kansas City, MO); Van Hook, Arthur (Lotawana, MO); Cook, Charles J. (Raytown, MO); Wenski, Edward G. (Lenexa, KS); Solyom, David (Overland Park, KS)

    2012-02-14T23:59:59.000Z

    A system and method for identifying, reporting, and evaluating a presence of a solid, liquid, gas, or other substance of interest, particularly a dangerous, hazardous, or otherwise threatening chemical, biological, or radioactive substance. The system comprises one or more substantially automated, location self-aware remote sensing units; a control unit; and one or more data processing and storage servers. Data is collected by the remote sensing units and transmitted to the control unit; the control unit generates and uploads a report incorporating the data to the servers; and thereafter the report is available for review by a hierarchy of responsive and evaluative authorities via a wide area network. The evaluative authorities include a group of relevant experts who may be widely or even globally distributed.

  7. System And Method For Identifying, Reporting, And Evaluating Presence Of Substance

    DOE Patents [OSTI]

    Smith, Maurice (Kansas City, MO); Lusby, Michael (Kansas City, MO); Hook, Arthur Van (Lake Lotawana, MO); Cook, Charles J. (Raytown, MO); Wenski, Edward G. (Lenexa, KS); Solyom, David (Overland Park, KS)

    2005-09-20T23:59:59.000Z

    A system and method for identifying, reporting, and evaluating a presence of a solid, liquid, gas, or other substance of interest, particularly a dangerous, hazardous, or otherwise threatening chemical, biological, or radioactive substance. The system comprises one or more substantially automated, location self-aware remote sensing units; a control unit; and one or more data processing and storage servers. Data is collected by the remote sensing units and transmitted to the control unit; the control unit generates and uploads a report incorporating the data to the servers; and thereafter the report is available for review by a hierarchy of responsive and evaluative authorities via a wide area network. The evaluative authorities include a group of relevant experts who may be widely or even globally distributed.

  8. One-Two-Three Punch Clobbers Toxic Algae, Restores Fremont Lake

    E-Print Network [OSTI]

    Nebraska-Lincoln, University of

    One-Two-Three Punch Clobbers Toxic Algae, Restores Fremont Lake Final Report Fremont Lake #20 Water-two-three punch to knockout toxic algae and restore water quality in Nebraska's numerous sandpit lakes. "It seems to help rid the too-often toxic algae prone Fremont State Lakes of the oily green scum that can close them

  9. An assessment of alternatives and technologies for replacing ozone- depleting substances at DOE facilities

    SciTech Connect (OSTI)

    Purcell, C.W.; Miller, K.B.; Friedman, J.R.; Rapoport, R.D.; Conover, D.R.; Hendrickson, P.L. [Pacific Northwest Lab., Richland, WA (United States); Koss, T.C. [USDOE Assistant Secretary for Environment, Safety, and Health, Washington, DC (United States). Office of Environmental Guidance

    1992-10-01T23:59:59.000Z

    Title VI of the Clean Air Act, as amended, mandates a production phase-out for ozone-depleting substances (ODSs). These requirements will have a significant impact on US Department of Energy (DOE) facilities. Currently, DOE uses ODSs in three major activities: fire suppression (halon), refrigeration and cooling (chlorofluorocarbons [CFCs]), and cleaning that requires solvents (CFCs, methyl chloroform, and carbon tetrachloride). This report provides basic information on methods and strategies to phase out use of ODSs at DOE facilities.

  10. Summary report: Trace substance emissions from a coal-fired gasification plant

    SciTech Connect (OSTI)

    Williams, A.; Wetherold, B.; Maxwell, D.

    1996-10-16T23:59:59.000Z

    The U.S. Department of Energy (DOE), the Electric Power Research Institute (EPRI), and Louisiana Gasification Technology Inc. (LGTI) sponsored field sampling and analyses to characterize emissions of trace substances from LGTI`s integrated gasification combined cycle (IGCC) power plant at Plaquemine, Louisiana. The results indicate that emissions from the LGTI facility were quite low, often in the ppb levels, and comparable to a well-controlled pulverized coal-fired power plant.

  11. Une mthode d'examen quantitatif des substances renfermant du radium

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    contiennent à côté du radium des substances sans émanation, comme l'uranium ou le polonium. Le principe de intégration où la constante d'intégration A est donnée par l'é(lua- tion. si l'on désigne par Eo la quantité d'émanation conte- nue dans l'enceinte au temps t=0. Pour le cas spé- cial où Eo==0 on a : et pour la valeur

  12. Evaluating guayule resin fractions for mutagenicity and toxicity 

    E-Print Network [OSTI]

    Avirett, Donald Baker

    1992-01-01T23:59:59.000Z

    microorganism, Il. The system measures the inhibitory effects of test substances upon the normal light producing ability of the bacteria. The purpose of this investigation was to assess several fractions of guayule resin for mutagenicity using the Ames ~a... Salm~ test is a short ? term microbial test using a mutant form of ~(IB~ EEI1~~g bacteria for assaying mutagenic activity of chemicals. It is termed an in-vitro test versus an in-vivo test (using laboratory animals), which is more expensive and time...

  13. Misonidazole with dexamethasone rescue: an escalating dose toxicity study

    SciTech Connect (OSTI)

    Tanasichuk, H.; Urtasun, R.C.; Fulton, D.S.; Raleigh, J.

    1984-09-01T23:59:59.000Z

    Neurotoxicity induced by misonidazole (MISO) and desmethylmisonidazole (DMM) has become the dose limiting factor in clinical work. In 1981, the authors reported a preliminary study suggestive that Dexamethasone (DEXA) does have a protective effect against peripheral neuropathies (PN) resulting from toxicity of misonidazole. The authors are presently investigating the use of DEXA, with escalating doses of MISO in an attempt to modify its neurotoxicity. To date, 16 patients have been registered to receive total doses of MISO given in 9 equally divided doses over 3 weeks. DEXA is given 3 days prior to the first dose and continues for the duration of therapy. All patients receive palliative radiation. No toxicity was seen at the total dose of 13.5 gm/M/sub 2/. One grade I PN occurred in the first four patients receiving 15.5 gm/M/sub 2/. Six additional patients were entered at this dose level and no further incidence of PN was observed.

  14. Collection and cultivation methods of Acartia tonsa for toxicity testing

    SciTech Connect (OSTI)

    Hood, C.A. [Baker Hughes INTEQ, Houston, TX (United States); Mayo, R.R. [ENSR Environmental Toxicology Lab., Houston, TX (United States)

    1995-12-31T23:59:59.000Z

    Acartia tonsa were located and collected from Galveston Bay, Texas in June 1995, using plankton nets and transported to the laboratory for culture. After literature searching and laboratory experimentation. A simple reliable method was designed to culture A. tonsa. This method requires a minimum of glassware and supplies. Adult A. tonsa are placed in one gallon bell jars filled with natural seawater. The jars are then maintained in a water bath at a constant temperature. Water changes are conducted twice weekly and organisms are fed daily with a mixture of algae, Skeletonema costatum, isocrysis galbana, and Thalassiosira sp. Gravid females are then isolated in generators for 24 hours to obtain known age neonates. The neonates are maintained up to a specific age and then are used in toxicity tests such as the ``Determination of the Acute Lethal Toxicity to Marine Copepods,`` required in the United Kingdom for all chemicals used for offshore drilling fluid applications.

  15. Systemic toxicity of dermally applied crude oils in rats

    SciTech Connect (OSTI)

    Feuston, M.H.; Mackerer, C.R.; Schreiner, C.A.; Hamilton, C.E. [Stonybrook Labs., Inc., Princeton, NJ (United States)] [Stonybrook Labs., Inc., Princeton, NJ (United States)

    1997-12-31T23:59:59.000Z

    Two crude oils, differing in viscosity (V) and nitrogen (N) and sulfur (S) content, were evaluated for systemic toxicity, In the Crude I (low V, low N, low S) study, the material was applied to the clipped backs of rats at dose levels of 0, 30, 125, and 500 mg/kg. In the Crude II (high V, high N, moderate S) study, the oil was applied similarly at the same dose levels. The crude oils were applied for 13 wk, 5 d/wk. Exposure sites were not occluded. Mean body weight gain (wk 1-14) was significantly reduced in male rats exposed to Crude II; body weight gain of all other animals was not adversely affected by treatment. An increase in absolute (A) and relative (R) liver weights and a decrease in A and R thymus weights were observed in male and female rats exposed to Crude II at 500 mg/kg; only liver weights (A and R) were adversely affected in male and female rats exposed to Crude I. In general, there was no consistent pattern of toxicity for serum chemistry endpoints; however, more parameters were adversely affected in Crude II-exposed female rats than in the other exposed groups. A consistent pattern of toxicity for hematology endpoints was observed among male rats exposed to Crude I and male and female rats exposed to Crude II. Parameters affected included: Crudes I and II, red blood cell count, hemoglobin, and hematocrit, Crude II, platelet count. Microscopic evaluation of tissues revealed the following treatment-related findings: Crude I, treated skin, thymus, and thyroid; Crude II, bone marrow, treated skin, thymus, and thyroid. The LOEL (lowest observable effect level) for skin irritation and systemic toxicity (based on marginal effects on the thyroid) for both crude oils was 30 mg/kg; effects were more numerous and more pronounced in animals exposed to Crude II. Systemic effects are probably related to concentrations of polycyclic aromatic compounds (PAC) found in crude oil.

  16. Reactive formulations for a neutralization of toxic industrial chemicals

    DOE Patents [OSTI]

    Tucker, Mark D. (Albuqueruqe, NM); Betty, Rita G. (Rio Rancho, NM)

    2006-10-24T23:59:59.000Z

    Decontamination formulations for neutralization of toxic industrial chemicals, and methods of making and using same. The formulations are effective for neutralizing malathion, hydrogen cyanide, sodium cyanide, butyl isocyanate, carbon disulfide, phosgene gas, capsaicin in commercial pepper spray, chlorine gas, anhydrous ammonia gas; and may be effective at neutralizing hydrogen sulfide, sulfur dioxide, formaldehyde, ethylene oxide, methyl bromide, boron trichloride, fluorine, tetraethyl pyrophosphate, phosphorous trichloride, arsine, and tungsten hexafluoride.

  17. Toxic and deadly: Working to manage algae in Lake Granbury

    E-Print Network [OSTI]

    Wythe, Kathy

    2011-01-01T23:59:59.000Z

    Toxic and deadly Working to manage algae in Lake Granbury Lake Granbury, located about 33 miles southwest of Fort Worth, is a recreation haven for water enthusiasts. In recent years, however, bacteria and golden algae have threatened the lake...?s water quality. Educating citizens about water quality issues affecting Lake Granbury and determining ways to manage the deadly algae are the focus of two Texas Water Resources Institute (TWRI) projects. Lake Granbury, a critical water supply...

  18. Toxic and deadly: Working to manage algae in Lake Granbury

    E-Print Network [OSTI]

    Wythe, Kathy

    2010-01-01T23:59:59.000Z

    Toxic and deadly Working to manage algae in Lake Granbury Lake Granbury, located about 33 miles southwest of Fort Worth, is a recreation haven for water enthusiasts. In recent years, however, bacteria and golden algae have threatened the lake...?s water quality. Educating citizens about water quality issues affecting Lake Granbury and determining ways to manage the deadly algae are the focus of two Texas Water Resources Institute (TWRI) projects. Lake Granbury, a critical water supply...

  19. Measurement of nitrogen content in a gas mixture by transforming the nitrogen into a substance detectable with nondispersive infrared detection

    DOE Patents [OSTI]

    Owen, Thomas E.; Miller, Michael A.

    2007-03-13T23:59:59.000Z

    A method of determining the amount of nitrogen in a gas mixture. The constituent gases of the mixture are dissociated and transformed to create a substance that may measured using nondispersive infrared adsorption techniques.

  20. Measurement of nitrogen content in a gas mixture by transforming the nitrogen into a substance detectable with nondispersive infrared detection

    DOE Patents [OSTI]

    Owen, Thomas E. (Helotes, TX); Miller, Michael A. (San Antonio, TX)

    2010-08-24T23:59:59.000Z

    A method of determining the amount of nitrogen in a gas mixture. The constituent gases of the mixture are dissociated and transformed to create a substance that may measured using nondispersive infrared adsorption techniques.

  1. Substance name

    E-Print Network [OSTI]

    unknown authors

    Hexachlorobutadiene is classified as a possible human carcinogen by the U.S. EPA. 1 HCBD is genotoxic in mammalian cell cultures and binds with DNA in rats and mice in vivo. 2 Studies in animals show a selective adverse effect of HCBD on the kidney, specifically the proximal tubule. 3,4 HCDB

  2. Use of neomysis mercedis (crustacea: mysidacea) for estuarine toxicity tests

    SciTech Connect (OSTI)

    Brandt, O.M.; Fujimura, R.W.; Finlayson, B.J. (Aquatic Toxicology Laboratory, Elk Grove, CA (United States))

    1993-03-01T23:59:59.000Z

    The mysid Neomysis mercedis was examined as a test organism for use in acute toxicity tests at intermediate salinities characteristic of estuarine waters. Several sensitive invertebrate species are available for marine assessments (mysids) and freshwater tests (cladocerans), but few are available for estuarine toxicity tests. Observations in the laboratory indicate that Neomysis mercedis can be reared successfully at a temperature of 17[degrees]C, a salinity of 2%, and a population density less than 5/L. Brine shrimp nauplii Artemia salina, algae, and commercial foods were used to sustain mysid cultures. Neomysis mercedis is vivaparous and can complete its life cycle in 3-4 months. Neomysis mercedis is as sensitive as or more sensitive to toxicants than the marine mysid Mysidopsis bahia and the freshwater cladocerans Daphnia magna, Ceriodaphnia dubia, and Simocephalus serrulatus. The mean 96-h LC50 values (concentrations lethal to half the test animals) for N. mercedis, in increasing order, were 0.20 [mu]g/L for thiobencarb, and for malathion, 14 [mu]g/L for carbofuran, 150 [mu]g/L for copper sulfate, 280 [mu]g/L for thiobencarb, and 1,600 [mu]g/L for molinate. Neonates (5 d postrelease) were generally more sensitive than older juveniles. Coefficients of variation (100[center dot]SD/mean) of LC50 values varied from 21 to 35%. 37 refs., 2 figs., 7 tabs.

  3. Air toxics evaluation of ABB Combustion Engineering Low-Emission Boiler Systems

    SciTech Connect (OSTI)

    Wesnor, J.D. [ABB/Combustion Engineering, Inc., Windsor, CT (United States)

    1993-10-26T23:59:59.000Z

    The specific goals of the program are to identify air toxic compounds that might be emmitted from the new boiler with its various Air Pollution Control device for APCD alternatives in levels of regulatory concern. For the compounds thought to be of concern, potential air toxic control methodologies will be suggested and a Test Protocol will be written to be used in the Proof of Concept and full scale tests. The following task was defined: Define Replations and Standards; Identify Air Toxic Pollutants of Interest to Interest to Utility Boilers; Assesment of Air Toxic By-Products; State of the Art Assessment of Toxic By-Product Control Technologies; and Test Protocol Definition.

  4. Annual site environmental report for calendar year 1999

    SciTech Connect (OSTI)

    NONE

    2000-04-14T23:59:59.000Z

    Many State and Federal environmental protection laws and regulations apply to Western. Western facilities are within the jurisdiction of six Environmental Protection Agency (EPA) regions and 17 states. Western's environmental policy statement directs employees to prevent, control, and abate environmental pollution at their facilities, and when possible, enhance the environment. To help assure conformance with all regulatory requirements, and to achieve its pollution prevention goals and objectives, Western is developing an Environmental Management System (EMS). One of the major regulatory impacts on Western continues to be the Toxic Substances Control Act (TSCA) that regulates the use of polychlorinated biphenyls (PCB). Western's policy is to eliminate PCBs from its system wherever economically and operationally possible. This will lessen the impact of PCB regulations on operations and the impact of PCBs on the environment. Executive Order 12856 requires Federal Agencies to comply with the Emergency Planning and Community Right-to-Know Act (EPCRA). As with other DOE elements, Western has been complying with EPCRA since before the Executive Order was issued. To summarize, in 1999, Western's Regional offices implemented programs to notify State and local emergency response entities in accordance with Section 311 and 312 of EPCRA. Chemical inventories indicate that Western does not manufacture, process, or otherwise use reportable quantities of EPCRA Section 313 chemicals so Toxic Release reports were not required.

  5. Comparative developmental toxicity of environmentally relevant oxygenated PAHs

    SciTech Connect (OSTI)

    Knecht, Andrea L., E-mail: andrea.knecht@tanguaylab.com [Department of Environmental and Molecular Toxicology, the Environmental Health Sciences Center, Oregon State University, Corvallis, OR (United States); Goodale, Britton C., E-mail: goodaleb@onid.orst.edu [Department of Environmental and Molecular Toxicology, the Environmental Health Sciences Center, Oregon State University, Corvallis, OR (United States); Truong, Lisa, E-mail: lisa.truong.888@gmail.com [Department of Environmental and Molecular Toxicology, the Environmental Health Sciences Center, Oregon State University, Corvallis, OR (United States); Simonich, Michael T., E-mail: mtsimonich@oregonstate.edu [Department of Environmental and Molecular Toxicology, the Environmental Health Sciences Center, Oregon State University, Corvallis, OR (United States); Swanson, Annika J., E-mail: swansoan@onid.orst.edu [Department of Environmental and Molecular Toxicology, the Environmental Health Sciences Center, Oregon State University, Corvallis, OR (United States); Matzke, Melissa M., E-mail: melissa.matzke@pnl.gov [Computational Biology and Bioinformatics, Pacific Northwest National Laboratory, Richland, WA (United States); Anderson, Kim A., E-mail: kim.anderson@oregonstate.edu [Department of Environmental and Molecular Toxicology, the Environmental Health Sciences Center, Oregon State University, Corvallis, OR (United States); Waters, Katrina M., E-mail: katrina.waters@pnl.gov [Computational Biology and Bioinformatics, Pacific Northwest National Laboratory, Richland, WA (United States); Tanguay, Robert L., E-mail: robert.tanguay@oregonstate.edu [Department of Environmental and Molecular Toxicology, the Environmental Health Sciences Center, Oregon State University, Corvallis, OR (United States)

    2013-09-01T23:59:59.000Z

    Oxygenated polycyclic aromatic hydrocarbons (OPAHs) are byproducts of combustion and photo-oxidation of parent PAHs. OPAHs are widely present in the environment and pose an unknown hazard to human health. The developing zebrafish was used to evaluate a structurally diverse set of 38 OPAHs for malformation induction, gene expression changes and mitochondrial function. Zebrafish embryos were exposed from 6 to 120 h post fertilization (hpf) to a dilution series of 38 different OPAHs and evaluated for 22 developmental endpoints. AHR activation was determined via CYP1A immunohistochemistry. Phenanthrenequinone (9,10-PHEQ), 1,9-benz-10-anthrone (BEZO), xanthone (XAN), benz(a)anthracene-7,12-dione (7,12-B[a]AQ), and 9,10-anthraquinone (9,10-ANTQ) were evaluated for transcriptional responses at 48 hpf, prior to the onset of malformations. qRT-PCR was conducted for a number of oxidative stress genes, including the glutathione transferase(gst), glutathione peroxidase(gpx), and superoxide dismutase(sod) families. Bioenergetics was assayed to measure in vivo oxidative stress and mitochondrial function in 26 hpf embryos exposed to OPAHs. Hierarchical clustering of the structure-activity outcomes indicated that the most toxic of the OPAHs contained adjacent diones on 6-carbon moieties or terminal, para-diones on multi-ring structures. 5-carbon moieties with adjacent diones were among the least toxic OPAHs while the toxicity of multi-ring structures with more centralized para-diones varied considerably. 9,10-PHEQ, BEZO, 7,12-B[a]AQ, and XAN exposures increased expression of several oxidative stress related genes and decreased oxygen consumption rate (OCR), a measurement of mitochondrial respiration. Comprehensive in vivo characterization of 38 structurally diverse OPAHs indicated differential AHR dependency and a prominent role for oxidative stress in the toxicity mechanisms. - Highlights: • OPAHs are byproducts of combustion present in the environment. • OPAHs pose a largely unknown hazard to human health. • We assayed the developmental toxicology of 39 different OPAHs in zebrafish. • The most toxic OPAHs contained adjacent diones or terminal, para-diones. • AHR dependency varied among OPAHs, and oxidative stress influenced their toxicology.

  6. Evaluation of Chemical Warfare Agent Percutaneous Vapor Toxicity: Derivation of Toxicity Guidelines for Assessing Chemical Protective Ensembles.

    SciTech Connect (OSTI)

    Watson, A.P.

    2003-07-24T23:59:59.000Z

    Percutaneous vapor toxicity guidelines are provided for assessment and selection of chemical protective ensembles (CPEs) to be used by civilian and military first responders operating in a chemical warfare agent vapor environment. The agents evaluated include the G-series and VX nerve agents, the vesicant sulfur mustard (agent HD) and, to a lesser extent, the vesicant Lewisite (agent L). The focus of this evaluation is percutaneous vapor permeation of CPEs and the resulting skin absorption, as inhalation and ocular exposures are assumed to be largely eliminated through use of SCBA and full-face protective masks. Selection of appropriately protective CPE designs and materials incorporates a variety of test parameters to ensure operability, practicality, and adequacy. One aspect of adequacy assessment should be based on systems tests, which focus on effective protection of the most vulnerable body regions (e.g., the groin area), as identified in this analysis. The toxicity range of agent-specific cumulative exposures (Cts) derived in this analysis can be used as decision guidelines for CPE acceptance, in conjunction with weighting consideration towards more susceptible body regions. This toxicity range is bounded by the percutaneous vapor estimated minimal effect (EME{sub pv}) Ct (as the lower end) and the 1% population threshold effect (ECt{sub 01}) estimate. Assumptions of exposure duration used in CPE certification should consider that each agent-specific percutaneous vapor cumulative exposure Ct for a given endpoint is a constant for exposure durations between 30 min and 2 hours.

  7. Pharmacokinetic drivers of toxicity for basic molecules: Strategy to lower pKa results in decreased tissue exposure and toxicity for a small molecule Met inhibitor

    SciTech Connect (OSTI)

    Diaz, Dolores, E-mail: diaz.dolores@gene.com [Safety Assessment, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080 (United States)] [Safety Assessment, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080 (United States); Ford, Kevin A. [Safety Assessment, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080 (United States)] [Safety Assessment, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080 (United States); Hartley, Dylan P. [Array Biopharma, Boulder, CO (United States)] [Array Biopharma, Boulder, CO (United States); Harstad, Eric B.; Cain, Gary R.; Achilles-Poon, Kirsten; Nguyen, Trung [Safety Assessment, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080 (United States)] [Safety Assessment, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080 (United States); Peng, Jing; Zheng, Zhong; Merchant, Mark [Translation Oncology, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080 (United States)] [Translation Oncology, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080 (United States); Sutherlin, Daniel P. [Medicinal Chemistry, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080 (United States)] [Medicinal Chemistry, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080 (United States); Gaudino, John J.; Kaus, Robert [Array Biopharma, Boulder, CO (United States)] [Array Biopharma, Boulder, CO (United States); Lewin-Koh, Sock C. [Biostatistics, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080 (United States)] [Biostatistics, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080 (United States); Choo, Edna F.; Liederer, Bianca M. [Drug Metabolism and Pharmacokinetics, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080 (United States)] [Drug Metabolism and Pharmacokinetics, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080 (United States); Dambach, Donna M. [Safety Assessment, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080 (United States)] [Safety Assessment, Genentech Inc., 1 DNA Way, South San Francisco, CA 94080 (United States)

    2013-01-01T23:59:59.000Z

    Several toxicities are clearly driven by free drug concentrations in plasma, such as toxicities related to on-target exaggerated pharmacology or off-target pharmacological activity associated with receptors, enzymes or ion channels. However, there are examples in which organ toxicities appear to correlate better with total drug concentrations in the target tissues, rather than with free drug concentrations in plasma. Here we present a case study in which a small molecule Met inhibitor, GEN-203, with significant liver and bone marrow toxicity in preclinical species was modified with the intention of increasing the safety margin. GEN-203 is a lipophilic weak base as demonstrated by its physicochemical and structural properties: high LogD (distribution coefficient) (4.3) and high measured pKa (7.45) due to the basic amine (N-ethyl-3-fluoro-4-aminopiperidine). The physicochemical properties of GEN-203 were hypothesized to drive the high distribution of this compound to tissues as evidenced by a moderately-high volume of distribution (Vd > 3 l/kg) in mouse and subsequent toxicities of the compound. Specifically, the basicity of GEN-203 was decreased through addition of a second fluorine in the 3-position of the aminopiperidine to yield GEN-890 (N-ethyl-3,3-difluoro-4-aminopiperidine), which decreased the volume of distribution of the compound in mouse (Vd = 1.0 l/kg), decreased its tissue drug concentrations and led to decreased toxicity in mice. This strategy suggests that when toxicity is driven by tissue drug concentrations, optimization of the physicochemical parameters that drive tissue distribution can result in decreased drug concentrations in tissues, resulting in lower toxicity and improved safety margins. -- Highlights: ? Lower pKa for a small molecule: reduced tissue drug levels and toxicity. ? New analysis tools to assess electrostatic effects and ionization are presented. ? Chemical and PK drivers of toxicity can be leveraged to improve safety.

  8. Mobile Source Air Toxics Rule (released in AEO2008)

    Reports and Publications (EIA)

    2008-01-01T23:59:59.000Z

    On February 9, 2007, the Environmental Protection Agency (EPA) released its MSAT2 rule, which will establish controls on gasoline, passenger vehicles, and portable fuel containers. The controls are designed to reduce emissions of benzene and other hazardous air pollutants. Benzene is a known carcinogen, and the EPA estimates that mobile sources produced more than 70% of all benzene emissions in 1999. Other mobile source air toxics, including 1,3-butadiene, formaldehyde, acetaldehyde, acrolein, and naphthalene, also are thought to increase cancer rates or contribute to other serious health problems.

  9. An evaluation of the whole effluent toxicity test method

    SciTech Connect (OSTI)

    Osteen, D.V.

    1999-12-17T23:59:59.000Z

    Whole effluent toxicity (WET) testing has become increasingly more important to the Environmental Protection Agency (EPA) and the States in the permitting of wastewater discharges from industry and municipalities. The primary purpose of the WET test is to protect aquatic life by predicting the effect of an effluent on the receiving stream. However, there are both scientific and regulatory concerns that using WET tests to regulate industrial effluents may result in either false positives and/or false negatives. In order to realistically predict the effect of an effluent on the receiving stream, the test should be as representative as possible of the conditions in the receiving stream. Studies (Rand and Petrocelli 1985) suggested several criteria for an ideal aquatic toxicity test organism, one of which is that the organism be indigenous to, or representative of, the ecosystem receiving the effluent. The other component needed in the development of a predictive test is the use of the receiving stream water or similar synthetic water as the control and dilution water in the test method. Use of an indigenous species and receiving water in the test should help reduce the variability in the method and allow the test to predict the effect of the effluent on the receiving stream. The experience with toxicity testing at the Savannah River Site (SRS) has yielded inconclusive data because of the inconsistency and unreliability of the results. The SRS contention is that the WET method in its present form does not adequately mimic actual biological/chemical conditions of the receiving streams and is neither reasonable nor accurate. This paper discusses the rationale for such a position by SRS on toxicity testing in terms of historical permitting requirements, outfall effluent test results, standard test method evaluation, scientific review of alternate test species, and concerns over the test method expressed by other organizations. This paper presents the Savannah River Site position that the EPA test is neither reasonable nor accurate and thus cannot adequately establish the impact of NPDES outfall discharges on receiving streams.

  10. Respiratory symptoms among glass bottle makers exposed to stannic chloride solution and other potentially hazardous substances

    SciTech Connect (OSTI)

    Levy, B.S.; Davis, F.; Johnson, B.

    1985-04-01T23:59:59.000Z

    Concern about upper respiratory tract irritation and other symptoms among workers at a glass bottle manufacturing plant led to an epidemiologic and an industrial hygiene survey. Questionnaire responses from 35 hot end and 53 cold end workers indicated that the incidence of wheezing, chest pain, dyspnea on exertion, and cough was significantly elevated among hot end workers. Among both smokers and nonsmokers, hot end workers reported higher, but not significantly higher, rates of wheezing and chest pain. Among smokers, hot end workers reported significantly higher rates of dyspnea on exertion and cough than did cold end workers. Data suggest that reported exposure to stannic chloride solution likely caused these symptoms. The industrial hygiene survey, conducted when stannic chloride use had been reduced, cleaning had been done, and ventilation improved, focused on measuring air contaminants that might possibly cause symptoms. Levels of hydrogen chloride, which apparently was formed by the combination of stannic chloride and water in the presence of heat, were elevated. The finding of increased prevalence of respiratory symptoms among hot end workers was consistent with this exposure. Recommendations were made to reduce hazardous exposures at this plant. Individuals responsible for occupational health should be aware that relatively benign substances, such as stannic chloride and water, can combine spontaneously to form hazardous substances.

  11. The fate of toxic pollutants in contaminated sediments

    SciTech Connect (OSTI)

    Yong, R.N. [McGill Univ., Montreal, Quebec (Canada)

    1995-12-31T23:59:59.000Z

    Sediments function as sinks for various kinds of contaminants (pollutants and nonpollutants) discharged into the receiving waters. Toxic pollutants in the sediments constitute a significant concern inasmuch as they can infect the waters above the sediment if they are released from the sediments. Hence the persistence and fate of these toxic pollutants need to be determined. At least tow sets of interests can be identified in the contamination of sediments as a whole: (1) assessment of the storage capacity (for contaminants) of the sediments, and the potential for mobilization or release of contaminants into the aqueous environment, particularly into the overlying water, and (2) development of a strategy for removal of the contaminants from the sediments that would be most appropriate (i.e., compatible with the manner in which the contaminants are retained in the sediment) and cost-effective. Both sets of interests require a knowledge of the distribution of the contaminants, i.e., characterization of the contaminants contained in the sediment, and the manner in which these are held within the sediment, i.e., bonded to the various sediment solid fractions (constituents). 56 refs., 11 figs., 3 tabs.

  12. Microbial stabilization and mass reduction of wastes containing radionuclides and toxic metals

    DOE Patents [OSTI]

    Francis, A.J.; Dodge, C.J.; Gillow, J.B.

    1991-09-10T23:59:59.000Z

    A process is provided to treat wastes containing radionuclides and toxic metals with Clostridium sp. BFGl to release a large fraction of the waste solids into solution and convert the radionuclides and toxic metals to a more concentrated and stable form with concurrent volume and mass reduction. The radionuclides and toxic metals being in a more stable form are available for recovery, recycling and disposal. 18 figures.

  13. LETTER Colonisation of toxic environments drives predictable life-history evolution in livebearing fishes (Poeciliidae)

    E-Print Network [OSTI]

    Schlupp, Ingo

    by the presence of toxic hydrogen sulphide (H2S). H2S is a widespread natural toxicant at deep-sea hydrothermal sources such as pulp mills or tanner- ies (Bagarinao 1992; Grieshaber & Volkel 1998). H2S is acutely toxic continuously high concentrations of H2S (e.g. Tobler et al. 2008b, 2011; Riesch et al. 2010a; Plath et al. 2013

  14. Microbial stabilization and mass reduction of wastes containing radionuclides and toxic metals

    DOE Patents [OSTI]

    Francis, Arokiasamy J. (Middle Island, NY); Dodge, Cleveland J. (Wading River, NY); Gillow, Jeffrey B. (Valley Cottage, NY)

    1991-01-01T23:59:59.000Z

    A process is provided to treat wastes containing radionuclides and toxic metals with Clostridium sp. BFGl to release a large fraction of the waste solids into solutin and convert the radionuclides and toxic metals to a more concentrated and stable form with concurrent volume and mass reduction. The radionuclides and toxic metals being in a more stable form are available for recovery, recycling and disposal.

  15. Acute toxicity of furazolidone on Artemia salina, Daphnia magna, and Culex pipiens molestus larvae

    SciTech Connect (OSTI)

    Macri, A.; Stazi, A.V.; Dojmi di Delupis, G.

    1988-10-01T23:59:59.000Z

    As a result of evidence of the ecotoxicity of nitrofurans, the acute toxicity of furazolidone was tested in vivo on two aquatic organisms, Artemia salina and Daphnia magna, which are both crustaceans. Toxicity studies were also performed on larvae of Culex pipiens molestus. Results indicated a significant toxicity of the compound on Culex pipiens and Daphnia magna, while Artemia salina proved to be the least sensitive.

  16. Standardized Total Average Toxicity Score: A Scale- and Grade-Independent Measure of Late Radiotherapy Toxicity to Facilitate Pooling of Data From Different Studies

    SciTech Connect (OSTI)

    Barnett, Gillian C., E-mail: gillbarnett@doctors.org.uk [University of Cambridge Department of Oncology, Oncology Centre, Cambridge (United Kingdom); Cancer Research-UK Centre for Genetic Epidemiology and Department of Oncology, Strangeways Research Laboratories, Cambridge (United Kingdom); West, Catharine M.L. [School of Cancer and Enabling Sciences, Manchester Academic Health Science Centre, University of Manchester, Christie Hospital, Manchester (United Kingdom); Coles, Charlotte E. [University of Cambridge Department of Oncology, Oncology Centre, Cambridge (United Kingdom); Pharoah, Paul D.P. [Cancer Research-UK Centre for Genetic Epidemiology and Department of Oncology, Strangeways Research Laboratories, Cambridge (United Kingdom); Talbot, Christopher J. [Department of Genetics, University of Leicester, Leicester (United Kingdom); Elliott, Rebecca M. [School of Cancer and Enabling Sciences, Manchester Academic Health Science Centre, University of Manchester, Christie Hospital, Manchester (United Kingdom); Tanteles, George A. [Department of Clinical Genetics, University Hospitals of Leicester, Leicester (United Kingdom); Symonds, R. Paul [Department of Cancer Studies and Molecular Medicine, University Hospitals of Leicester, Leicester (United Kingdom); Wilkinson, Jennifer S. [University of Cambridge Department of Oncology, Oncology Centre, Cambridge (United Kingdom); Dunning, Alison M. [Cancer Research-UK Centre for Genetic Epidemiology and Department of Oncology, Strangeways Research Laboratories, Cambridge (United Kingdom); Burnet, Neil G. [University of Cambridge Department of Oncology, Oncology Centre, Cambridge (United Kingdom); Bentzen, Soren M. [University of Wisconsin, School of Medicine and Public Health, Department of Human Oncology, Madison, WI (United States)

    2012-03-01T23:59:59.000Z

    Purpose: The search for clinical and biologic biomarkers associated with late radiotherapy toxicity is hindered by the use of multiple and different endpoints from a variety of scoring systems, hampering comparisons across studies and pooling of data. We propose a novel metric, the Standardized Total Average Toxicity (STAT) score, to try to overcome these difficulties. Methods and Materials: STAT scores were derived for 1010 patients from the Cambridge breast intensity-modulated radiotherapy trial and 493 women from University Hospitals of Leicester. The sensitivity of the STAT score to detect differences between patient groups, stratified by factors known to influence late toxicity, was compared with that of individual endpoints. Analysis of residuals was used to quantify the effect of these covariates. Results: In the Cambridge cohort, STAT scores detected differences (p < 0.00005) between patients attributable to breast volume, surgical specimen weight, dosimetry, acute toxicity, radiation boost to tumor bed, postoperative infection, and smoking (p < 0.0002), with no loss of sensitivity over individual toxicity endpoints. Diabetes (p = 0.017), poor postoperative surgical cosmesis (p = 0.0036), use of chemotherapy (p = 0.0054), and increasing age (p = 0.041) were also associated with increased STAT score. When the Cambridge and Leicester datasets were combined, STAT was associated with smoking status (p < 0.00005), diabetes (p = 0.041), chemotherapy (p = 0.0008), and radiotherapy boost (p = 0.0001). STAT was independent of the toxicity scale used and was able to deal with missing data. There were correlations between residuals of the STAT score obtained using different toxicity scales (r > 0.86, p < 0.00005 for both datasets). Conclusions: The STAT score may be used to facilitate the analysis of overall late radiation toxicity, from multiple trials or centers, in studies of possible genetic and nongenetic determinants of radiotherapy toxicity.

  17. Identification and evaluation of the nonradioactive toxic components in LLNL weapon designs, Phase 1

    SciTech Connect (OSTI)

    Johnson, J.A.; Lipska-Quinn, A.E.

    1994-01-01T23:59:59.000Z

    The proper industrial hygiene strategy and response to a weapons accident is dependent upon the nonradioactive toxic materials contained in each weapon system. For example, in order to use the proper sampling and support equipment, e.g., personal protective and air sampling equipment, the Accident Response Group (ARG) Team needs a detailed inventory of nonradioactive toxic and potentially toxic materials in the weapon systems. The DOE Albuquerque Office or Operations funded the Lawrence Livermore National Laboratory (LLNL), Los Alamos National Laboratory (LANL) and Sandia National Laboratory to identify and evaluate the nonradioactive toxic components of their respective weapons designs. This report summarizes LLNL`s first year`s activities and results.

  18. On-Line Microbial Whole Effluent Toxicity Monitoring for Industrial Wastewater

    SciTech Connect (OSTI)

    Mathews, S; Hoppes, W; Mascetti, M; Campbell, C G

    2002-09-17T23:59:59.000Z

    In this study a respirometer is tested for its ability to act as an early upset warning device and whole effluent toxicity monitor for industrial discharge. Industrial discharge water quality is commonly evaluated by comparing measured chemical concentrations to target values or regulatory limits established by governmental agencies. Unless the regulatory values are based upon empirical data, the actual effect of the discharge on aquatic systems is unknown. At the same time assessing the environmental toxicology of wastewater discharges is complicated by synergistic relationships among chemical constituents producing greater total toxicity. For example, metals may be more toxic in waters with low total hardness or more soluble at lower pH. An alternative approach that we are investigating is whole effluent toxicity testing. This study investigates the measurement of whole effluent toxicity through an on-line respirometer that measures toxicity to microorganisms comprising activated sludge. In this approach the oxygen uptake rate is monitored and used as an indicator of microbial activity or health. This study investigates the use of an online whole effluent toxicity testing system to provide early upset warning and the consistency of measured response to low pH. Repeated exposure of the microorganisms to low pH results in reduced sensitivity of the microbial population. We investigate whether this reduction in sensitivity results from physiological acclimation or changes in species composition. We identify promising applications, where, with proper calibration, respirometry based toxicity monitoring appear to be well suited for relative comparisons of whole effluent toxicity.

  19. E-Print Network 3.0 - acute liver toxicity Sample Search Results

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    injury. When injury is acute, the fibrotic response is taken over by regeneration... to carbon tetrachloride-induced toxicity as compared to human ... Source: Groningen,...

  20. Pentose fermentation of normally toxic lignocellulose prehydrolysate with strain of Pichia stipitis yeast using air

    DOE Patents [OSTI]

    Keller, Jr., Fred A. (Lakewood, CO); Nguyen, Quang A. (Golden, CO)

    2002-01-01T23:59:59.000Z

    Strains of the yeast Pichia stipitis NPw9 (ATCC PTA-3717) useful for the production of ethanol using oxygen for growth while fermenting normally toxic lignocellulosic prehydrolysates.

  1. Bacterial chemotaxis towards the extracellular products of the toxic phytoplankton Heterosigma akashiwo

    E-Print Network [OSTI]

    Stocker, Roman

    Marine bacteria exhibit positive chemotactic responses to the extracellular exudates of the toxic phytoplankton Heterosigma akashiwo. In the environment, this will support bacteria–algae associations with potential ...

  2. Is lead toxicity still a risk to U.S. children?

    E-Print Network [OSTI]

    Heneman, Karrie M.; Zidenberg-Cherr, Sheri

    2006-01-01T23:59:59.000Z

    in children with blood lead concentrations below 10 microgchocolate pieces monitoring of lead levels Milk chocolatethe risk Candy-coated of lead toxicity from these chocolate

  3. Use Of The Evidence Base In Substance Abuse Treatment Programs for American Indians and Alaska Natives: Pursuing Quality in the Crucible Of Practice And Policy

    E-Print Network [OSTI]

    2011-01-01T23:59:59.000Z

    Abuse Treatment Capacity in Targeted Areas of Need-Local Recovery-Oriented Systems of Care (care systems and have varying approaches to substance abuse treatment [

  4. Postoperative Intensity-Modulated Arc Therapy for Cervical and Endometrial Cancer: A Prospective Report on Toxicity

    SciTech Connect (OSTI)

    Vandecasteele, Katrien, E-mail: Katrien.Vandecasteele@uzgent.be [Department of Radiation Oncology, Ghent University Hospital, Ghent (Belgium)] [Department of Radiation Oncology, Ghent University Hospital, Ghent (Belgium); Tummers, Philippe; Makar, Amin [Department of Gynecologic Oncology, Ghent University Hospital, Ghent (Belgium)] [Department of Gynecologic Oncology, Ghent University Hospital, Ghent (Belgium); Eijkeren, Marc van [Department of Radiation Oncology, Ghent University Hospital, Ghent (Belgium)] [Department of Radiation Oncology, Ghent University Hospital, Ghent (Belgium); Delrue, Louke [Department of Radiology, Ghent University Hospital, Ghent (Belgium)] [Department of Radiology, Ghent University Hospital, Ghent (Belgium); Denys, Hannelore [Department of Medical Oncology, Ghent University Hospital, Ghent (Belgium)] [Department of Medical Oncology, Ghent University Hospital, Ghent (Belgium); Lambert, Bieke [Department of Nuclear Medicine, Ghent University Hospital, Ghent (Belgium)] [Department of Nuclear Medicine, Ghent University Hospital, Ghent (Belgium); Beerens, Anne-Sophie [Department of Pathology, Ghent University Hospital, Ghent (Belgium)] [Department of Pathology, Ghent University Hospital, Ghent (Belgium); Van den Broecke, Rudy [Department of Gynecologic Oncology, Ghent University Hospital, Ghent (Belgium)] [Department of Gynecologic Oncology, Ghent University Hospital, Ghent (Belgium); Lambein, Kathleen [Department of Pathology, Ghent University Hospital, Ghent (Belgium)] [Department of Pathology, Ghent University Hospital, Ghent (Belgium); Fonteyne, Valerie; De Meerleer, Gert [Department of Radiation Oncology, Ghent University Hospital, Ghent (Belgium)] [Department of Radiation Oncology, Ghent University Hospital, Ghent (Belgium)

    2012-10-01T23:59:59.000Z

    Purpose: To report on toxicity after postoperative intensity-modulated arc therapy (IMAT) for cervical (CC) and endometrial cancer (EC). Methods and Materials: Twenty-four CC and 41 EC patients were treated with postoperative IMAT. If indicated, para-aortic lymph node irradiation (preventive or when affected, PALN) and/or concomitant cisplatin (40 mg/m Superscript-Two , weekly) was administered. The prescribed dose for IMAT was 45 Gy (CC, 25 fractions) and 46 Gy (EC, 23 fractions), followed by a brachytherapeutic boost if possible. Radiation-related toxicity was assessed prospectively. The effect of concomitant cisplatin and PALN irradiation was evaluated. Results: Regarding acute toxicity (n = 65), Grade 3 and 2 acute gastrointestinal toxicity was observed in zero and 63% of patients (79% CC, 54% EC), respectively. Grade 3 and 2 acute genitourinary toxicity was observed in 1% and 18% of patients, respectively. Grade 2 (21%) and 3 (12%) hematologic toxicity (n = 41) occurred only in CC patients. Seventeen percent of CC patients and 2% of EC patients experienced Grade 2 fatigue and skin toxicity, respectively. Adding cisplatin led to an increase in Grade >2 nausea (57% vs. 9%; p = 0.01), Grade 2 nocturia (24% vs. 4%; p = 0.03), Grade {>=}2 hematologic toxicity (38% vs. nil, p = 0.003), Grade {>=}2 leukopenia (33% vs. nil, p = 0.009), and a strong trend toward more fatigue (14% vs. 2%; p = 0.05). Para-aortic lymph node irradiation led to an increase of Grade 2 nocturia (31% vs. 4%, p = 0.008) and a strong trend toward more Grade >2 nausea (44% vs. 18%; p = 0.052). Regarding late toxicity (n = 45), no Grade 3 or 4 late toxicity occurred. Grade 2 gastrointestinal toxicity, genitourinary toxicity, and fatigue occurred in 4%, 9%, and 1% of patients. Neither concomitant cisplatin nor PALN irradiation increased late toxicity rates. Conclusions: Postoperative IMAT for EC or CC is associated with low acute and late toxicity. Concomitant chemotherapy and PALN irradiation influences acute but not late toxicity.

  5. Method and apparatus for diagnosis of lead toxicity

    DOE Patents [OSTI]

    Rosen, John F. (Riverside, CT); Slatkin, Daniel N. (Bayside, NY); Wielopolski, Lucian (Shirley, NY)

    1989-01-01T23:59:59.000Z

    Improved methods and apparatus for in vivo measurement of the skeletal lead burden of a patient and for diagnosis of lead toxicity are disclosed. The apparatus comprises an x-ray tube emitting soft low energy x-rays from a silver anode, a polarizer for polarizing the emitted x-rays, and a detector for detecting photons fluoresced from atoms in the patient's tibia upon irradiation by the polarized x-rays. The fluoresced photons are spectrally analyzed to determine their energy distribution. Peaks indicating the presence of lead are identified if the patient has relatively high bone lead content. The data may be compared to data recorded with respect to a similar test performed on patients having also had the conventional EDTA chelation tests performed thereon in order to correlate the test results with respect to a particular patient to the conventionally accepted EDTA chelation test.

  6. Models for environmental impact assessments of releases of radioactive substances from CERN facilities

    E-Print Network [OSTI]

    Vojtyla, P

    2005-01-01T23:59:59.000Z

    The document describes generic models for environmental impact assessments of releases of radioactive substances from CERN facilities. Except for few models developed in the Safety Commission, the models are based on the 1997 Swiss directive HSK-R-41 and on the 2001 IAEA Safety Report No. 19. The writing style is descriptive, facilitating the practical implementation of the models at CERN. There are four scenarios assumed for airborne releases: (1) short-term releases for release limit calculations, (2) actual short-term releases, (3) short-term releases during incidents/accidents, and (4) chronic long-term releases during the normal operation of a facility. For water releases, two scenarios are considered: (1) a release into a river, and (2) a release into a water treatment plant. The document shall be understood as a reference for specific environmental studies involving radioactive releases and as a recommendation of the Safety Commission.

  7. Statistical properties of an algorithm used for illicit substance detection by fast-neutron transmission

    SciTech Connect (OSTI)

    Smith, D.L.; Sagalovsky, L.; Micklich, B.J.; Harper, M.K.; Novick, A.H.

    1994-06-01T23:59:59.000Z

    A least-squares algorithm developed for analysis of fast-neutron transmission data resulting from non-destructive interrogation of sealed luggage and containers is subjected to a probabilistic interpretation. The approach is to convert knowledge of uncertainties in the derived areal elemental densities, as provided by this algorithm, into probability information that can be used to judge whether an interrogated object is either benign or potentially contains an illicit substance that should be investigated further. Two approaches are considered in this paper. One involves integration of a normalized probability density function associated with the least-squares solution. The other tests this solution against a hypothesis that the interrogated object indeed contains illicit material. This is accomplished by an application of the F-distribution from statistics. These two methods of data interpretation are applied to specific sets of neutron transmission results produced by Monte Carlo simulation.

  8. Mathematical model of the seismic electromagnetic signals (SEMS) in non crystalline substances

    SciTech Connect (OSTI)

    Dennis, L. C. C.; Yahya, N.; Daud, H.; Shafie, A. [Electromagnetic cluster, Universiti Teknologi Petronas, 31750 Tronoh, Perak (Malaysia)

    2012-09-26T23:59:59.000Z

    The mathematical model of seismic electromagnetic waves in non crystalline substances is developed and the solutions are discussed to show the possibility of improving the electromagnetic waves especially the electric field. The shear stress of the medium in fourth order tensor gives the equation of motion. Analytic methods are selected for the solutions written in Hansen vector form. From the simulated SEMS, the frequency of seismic waves has significant effects to the SEMS propagating characteristics. EM waves transform into SEMS or energized seismic waves. Traveling distance increases once the frequency of the seismic waves increases from 100% to 1000%. SEMS with greater seismic frequency will give seismic alike waves but greater energy is embedded by EM waves and hence further distance the waves travel.

  9. www.btny.purdue.edu/weedscience/ Poison Hemlock The Toxic Parsnip

    E-Print Network [OSTI]

    Ginzel, Matthew

    www.btny.purdue.edu/weedscience/ Poison Hemlock ­ The Toxic Parsnip We often get questions about wild carrot (Daucus carota L.) only to find out that the question is actually about poison hemlock (Conium maculatum L.). Although these two plants may look similar, poison hemlock is toxic to cattle

  10. Sub-lethal ammonia toxicity in largemouth bass C.D. Suski a,,1

    E-Print Network [OSTI]

    Suski, Cory David

    . Exposure to 100 M Tamm impaired the ability of largemouth bass to recover from exercise relative to fishSub-lethal ammonia toxicity in largemouth bass C.D. Suski a,,1 , J.D. Kieffer b , S.S. Killen a,2 Available online 24 November 2006 Abstract Guidelines for ammonia toxicity in fish are often determined

  11. How much ``weight`` should be assigned to toxicity test results in ecological risk assessment?

    SciTech Connect (OSTI)

    Hull, R.N.; Gilron, G.L. [Beak Consultants Ltd., Brampton, Ontario (Canada)

    1995-12-31T23:59:59.000Z

    Toxicity tests are an integral part of ecological assessment activities such as Canada`s Environmental Effects Monitoring (EEM) programs and the USA`s Superfund program. Both of these types of programs encourage the use of the weight-of-evidence approach for the evaluation of ecological risks. This approach uses data from biological surveys, toxicity tests, and ambient media chemical analyses. Currently, there is no guidance available which identifies the relative importance of these different data types in the risk assessment. The quality of the data generated will necessarily determine the ``weight`` assigned to each line of evidence. Decisions often are made on the basis of toxicity test results. However, routine tests are conducted frequently without consideration of their appropriateness (e.g., species sensitivity, ecological relevance). Therefore, an evaluation was conducted to determine the relative sensitivities of various test methods used to assess toxicity from various industries. Different industries were selected to represent different classes of contaminants. For example, the pulp and paper industry releases organic compounds and the mining sector primarily releases heavy metals. The comparative sensitivities of toxicity tests will be illustrated for two industrial sector case studies. With a better understanding of toxicity test method sensitivity, the ecological risk assessor is better able to assign the appropriate weight to the toxicity test results in a risk characterization. This will allow toxicity testing programs to be focused and increase the confidence in the entire risk assessment and any resulting decisions.

  12. UNDERSTANDING THE GENETIC CONSEQUENCES OF ENVIRONMENTAL TOXICANT EXPOSURE: CHERNOBYL AS A MODEL SYSTEM

    E-Print Network [OSTI]

    Baker, Robert J.

    UNDERSTANDING THE GENETIC CONSEQUENCES OF ENVIRONMENTAL TOXICANT EXPOSURE: CHERNOBYL AS A MODEL to Chernobyl radiation. Our results suggest that genetic diversity in radioactive regions of Ukraine to elucidate the effects of toxicant exposure. Keywords--Chernobyl Bank vole Population genetics Comparative

  13. Does a toxic fungal endophyte of tall fescue affect reproduction of

    E-Print Network [OSTI]

    Jamieson, Ian

    Does a toxic fungal endophyte of tall fescue affect reproduction of takahe on offshore islands? DOC. References 9 #12;4 Jamieson & Easton--Tall fescue-endophytes and takahe reproction on offshore islands Final of Conservation. This paper may be cited as: Jamieson, I.; Sydney Easton, H. 2002: Does a toxic fungal endophyte

  14. Modulation of the Toxicity and Macromolecular Binding of Benzene Metabolites by NAD(P)H:Quinone

    E-Print Network [OSTI]

    California at Berkeley, University of

    Articles Modulation of the Toxicity and Macromolecular Binding of Benzene Metabolites by NAD, San Francisco, California 94143-0560 Received April 17, 1998 Benzene is oxidized in the liver of benzene metabolite toxicity. NQO1 expression reduced a class of hydroquinone- and benzenetriol-induced DNA

  15. Field Validation of Toxicity Tests to Evaluate the Potential for Beneficial Use of Produced Water

    SciTech Connect (OSTI)

    Joseph Bidwell; Jonathan Fisher; Naomi Cooper

    2008-03-31T23:59:59.000Z

    This study investigated potential biological effects of produced water contamination derived from occasional surface overflow and possible subsurface intrusion at an oil production site along the shore of Skiatook Lake, Oklahoma. We monitored basic chemistry and acute toxicity to a suite of standard aquatic test species (fathead minnow-Pimephales promelas, Daphnia pulex, Daphnia magna, and Ceriodaphnia dubia) in produced water and in samples taken from shallow groundwater wells on the site. Toxicity identification evaluations and ion toxicity modeling were used to identify toxic constituents in the samples. Lake sediment at the oil production site and at a reference site were also analyzed for brine intrusion chemically and by testing sediment toxicity using the benthic invertebrates, Chironomus dilutus, and Hyallela azteca. Sediment quality was also assessed with in situ survival and growth studies with H. azteca and the Asian clam, Corbicula fluminea, and by benthic macroinvertebrate community sampling. The produced water was acutely toxic to the aquatic test organisms at concentrations ranging from 1% to 10% of the whole produced water sample. Toxicity identification evaluation and ion toxicity modeling indicated major ion salts and hydrocarbons were the primary mixture toxicants. The standardized test species used in the laboratory bioassays exhibited differences in sensitivity to these two general classes of contaminants, which underscores the importance of using multiple species when evaluating produced water toxicity. Toxicity of groundwater was greater in samples from wells near a produced water injection well and an evaporation pond. Principle component analyses (PCA) of chemical data derived from the groundwater wells indicated dilution by lake water and possible biogeochemical reactions as factors that ameliorated groundwater toxicity. Elevated concentrations of major ions were found in pore water from lake sediments, but toxicity from these ions was limited to sediment depths of 10 cm or greater, which is outside of the primary zone of biological activity. Further, exposure to site sediments did not have any effects on test organisms, and macroinvertebrate communities did not indicate impairment at the oil production site as compared to a reference site. In situ experiments with H. azteca and C. fluminea, indicated a sublethal site effect (on growth of both species), but these could not be definitively linked with produced water infiltration. Severe weather conditions (drought followed by flooding) negatively influenced the intensity of lake sampling aimed at delineating produced water infiltration. Due to the lack of clear evidence of produced water infiltration into the sub-littoral zone of the lake, it was not possible to assess whether the laboratory bioassays of produced water effectively indicate risk in the receiving system. However, the acutely toxic nature of the produced water and general lack of biological effects in the lake at the oil production site suggest minimal to no produced water infiltration into surficial lake sediments and the near-shore water column. This study was able to demonstrate the utility of ion toxicity modeling to support data from toxicity identification evaluations aimed at identifying key toxic constituents in produced water. This information could be used to prioritize options for treating produced water in order to reduce toxic constituents and enhance options for reuse. The study also demonstrated how geographic information systems, toxicity modeling, and toxicity assessment could be used to facilitate future site assessments.

  16. Aquatic toxicity information on VAX VMS backup (ACQUIRE for VMS). Data file

    SciTech Connect (OSTI)

    Not Available

    1991-09-01T23:59:59.000Z

    The purpose of Acquire is to provide scientists and managers quick access to a comprehensive, systematic, computerized compilation of aquatic toxicity data. Scientific papers published both nationally and internationally on the toxicity of chemicals to aquatic organisms and plants are collected and reviewed for ACQUIRE. Independently compiled data files that meet ACQUIRE parameter and quality assurance criteria are also included. Selected toxicity test results and related testing information for any individual chemical from laboratory and field aquatic toxicity effects are included for tests with freshwater and marine organisms. The total number of data records in ACQUIRE is now over 105,300. This includes data from 6000 references, for 5200 chemicals and 2400 test species. A major data file, Acute Toxicity of Organic Chemicals (ATOC), has been incorporated into ACQUIRE. The ATOC file contains laboratory acute test data on 525 organic chemicals using juvenile fathead minnows.

  17. Environmental impact assessment of tailings dispersal from a uranium mine using toxicity testing protocols

    SciTech Connect (OSTI)

    Rippon, G.D. [Environmental Protection Agency, Canberra (Australia); Riley, S.J. [Univ. of Western Sydney-Nepean, Kingswood (Australia)

    1996-12-01T23:59:59.000Z

    Toxicity testing is a means of establishing the environmental risk of uranium tailings release. It is valuable in designing tailings containment structures because it assists in setting acceptable levels of risk of the design. This paper presents details of toxicity tests of the tailings from Ranger Uranium Mine, Northern Territory, Australia. The results suggest that the non-radiological toxicity of the tailings is low. The environmental risk of a tailings release is more likely to be related to the physical impacts of the tailings, including infilling of billabongs and changes in the sedimentology of riparian ecosystems rather than their biogeochemical impact. Two major results were: (1) water from treatment with washed tailing fines was not toxic to Hydra viridissima, and (2) mixtures of washed tailings fines and natural floodplain sediment (overlying water or elutriates) were not toxic to Hydra viridissima or Moinodaphnia macleayi. 33 refs., 4 figs., 3 tabs.

  18. Investigation of the metabolism of Substance-P at the blood-brain barrier using LC-MS/MS

    E-Print Network [OSTI]

    Chappa, Arvind K.; Cooper, Joshua D.; Audus, Kenneth L.; Lunte, Susan M.

    2007-01-01T23:59:59.000Z

    , the metabolism of SP was investigated using an in vitro model of the BBB and LC-MS/MS. Substance P metabolism was found to be non-saturable in the concentration range of 100 nM to 10 ?M, with approximately 70% of the peptide remaining intact after 5 hrs...

  19. "Smoking Cessation Interventions and Program Availability for Drug and Alcohol Addicted Low Income Populations in Substance Abuse Treatment"

    E-Print Network [OSTI]

    Arnold, Jonathan

    "Smoking Cessation Interventions and Program Availability for Drug and Alcohol Addicted Low Income. The first aim examines longitudinally the availability of EBTs for smoking among those seeking treatment for co-occurring substance abuse and explores the predictors of changes in service availability over time

  20. Safe Method of Use for Hazardous Substances of Higher Risk 16 Version 2 July 2008 Page 1 of 5

    E-Print Network [OSTI]

    Auckland, University of

    Safe Method of Use for Hazardous Substances of Higher Risk 16 Version 2 July 2008 Page 1 of 5 SafeBr depend on the nature of the waste materials and the concentration of EtBr that they contain. Much a choice of protocols, the sodium nitrite method is preferred as the reaction products retain very little

  1. IMPAIRED PHYSICIAN FOCUS ON SUBSTANCE ABUSE 1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders IV.

    E-Print Network [OSTI]

    Yates, Andrew

    IMPAIRED PHYSICIAN FOCUS ON SUBSTANCE ABUSE REFERENCES 1 1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders IV. 4th ed. Washington, DC: American Psychiatric Association; 1994. 2. American Society of Addiction Medicine. Patient Placement Criteria for the Treatment

  2. Product consistency test and toxicity characteristic leaching procedure results of the ceramic waste form from the electrometallurgical treatment process for spent fuel

    SciTech Connect (OSTI)

    Johnson, S. G.; Adamic, M. L.: DiSanto, T.; Warren, A. R.; Cummings, D. G.; Foulkrod, L.; Goff, K. M.

    1999-11-11T23:59:59.000Z

    The ceramic waste form produced from the electrometallurgical treatment of sodium bonded spent fuel from the Experimental Breeder Reactor-II was tested using two immersion tests with separate and distinct purposes. The product consistency test is used to assess the consistency of the waste forms produced and thus is an indicator of a well-controlled process. The toxicity characteristic leaching procedure is used to determine whether a substance is to be considered hazardous by the Environmental Protection Agency. The proposed high level waste repository will not be licensed to receive hazardous waste, thus any waste forms destined to be placed there cannot be of a hazardous nature as defined by the Resource Conservation and Recovery Act. Results are presented from the first four fully radioactive ceramic waste forms produced and from seven ceramic waste forms produced from cold surrogate materials. The fully radioactive waste forms are approximately 2 kg in weight and were produced wit h salt used to treat 100 driver subassemblies of spent fuel.

  3. Protective effects of lipoic acid on chrysene-induced toxicity on M?ller cells in vitro

    E-Print Network [OSTI]

    Mansoor, Saffar; Gupta, Navin; Luczy-Bachman, Georgia; Limb, G. Astrid; Kuppermann, Baruch D.; Kenney, M. Cristina

    2013-01-01T23:59:59.000Z

    Ames BN, Cotman CW, Liu J. Acrolein, a toxicant in cigarette31. Li L, Holian A. Acrolein: a respiratory toxin thatJia et al. reported that acrolein, a toxicant in cigarette

  4. Role of aggregation conditions and presence of small heat shock proteins on abeta structure, stability and toxicity 

    E-Print Network [OSTI]

    Lee, Sung Mun

    2006-08-16T23:59:59.000Z

    to the most toxic ?? species change their structure the most rapidly in denaturant, and that in general, increased toxicity correlated with decreased aggregate stability. In AlzheimerÂ?s disease, even delaying A? aggregation onset or slowing its...

  5. Waste Isolation Pilot Plant Biennial Environmental Compliance Report

    SciTech Connect (OSTI)

    Washington Regulatory and Environmental Services

    2006-10-12T23:59:59.000Z

    This Biennial Environmental Compliance Report (BECR) documents compliance with environmental regulations at the Waste Isolation Pilot Plant (WIPP), a facility designed and authorized for the safe disposal of transuranic (TRU) radioactive waste. This BECR covers the reporting period from April 1, 2004, to March 31, 2006. As required by the WIPP Land Withdrawal Act (LWA) (Public Law [Pub. L.] 102-579, as amended by Pub. L. 104-201), the BECR documents United States (U.S.) Department of Energy (DOE) compliance with regulations and permits issued pursuant to the following: (1) Title 40 Code of Federal Regulations (CFR) Part 191, Subpart A, "Environmental Standards for Management and Storage"; (2) Clean Air Act (CAA) (42 United States Code [U.S.C.] §7401, et seq.); (3) Solid Waste Disposal Act (SWDA) (42 U.S.C. §§6901-6992, et seq.); (4) Safe Drinking Water Act (SDWA) (42 U.S.C. §§300f, et seq.); (5) Toxic Substances Control Act (TSCA) (15 U.S.C. §§2601, et seq.); (6) Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) (42 U.S.C. §§9601, et seq.); and all other federal and state of New Mexico laws pertaining to public health and safety or the environment.

  6. Basic Engineering Research for D and D of R Reactor Storage Pond Sludge: Electrokinetics, Carbon Dioxide Extraction, and Supercritical Water Oxidation

    SciTech Connect (OSTI)

    Michael A. Matthews; David A. Bruce,; Thomas A. Davis; Mark C. Thies; John W. Weidner; Ralph E. White

    2002-04-01T23:59:59.000Z

    Large quantities of mixed low level waste (MLLW) that fall under the Toxic Substances Control Act (TSCA) exist and will continue to be generated during D and D operations at DOE sites across the country. The standard process for destruction of MLLW is incineration, which has an uncertain future. The extraction and destruction of PCBs from MLLW was the subject of this research Supercritical Fluid Extraction (SFE) with carbon dioxide with 5% ethanol as cosolvent and Supercritical Waster Oxidation (SCWO) were the processes studied in depth. The solid matrix for experimental extraction studies was Toxi-dry, a commonly used absorbent made from plant material. PCB surrogates were 1.2,4-trichlorobenzene (TCB) and 2-chlorobiphenyl (2CBP). Extraction pressures of 2,000 and 4,000 psi and temperatures of 40 and 80 C were studied. Higher extraction efficiencies were observed with cosolvent and at high temperature, but pressure little effect. SCWO treatment of the treatment of the PCB surrogates resulted in their destruction below detection limits.

  7. Field demonstration of the LINDE Oxygen Combustion System on the EPA mobile incinerator

    SciTech Connect (OSTI)

    Ho, M.D.; Perdek, J.M.; Stumbar, J.P.; Sawyer, R.H.

    1992-01-01T23:59:59.000Z

    The paper summarizes the various system performance tests and the long-term operating experience of the LINDE Oxygen Combustion System (OCS) installed on the U.S. Environmental Protection Agency's (EPA) Mobile Incineration System (MIS) when it was in operation at the Denney Farm site in southwestern Missouri. The LINDE OCS was installed on the MIS as part of a major modification program in 1987. The modified system was first demonstrated for three months in 1987 when various system performance tests were conducted. Test burns of the modified MIS showed destruction and removal efficiencies (DRE) surpassing both Resource Conservation and Recovery Act (RCRA) and Toxic Substances Control Act (TSCA) standards. The system resumed operation in February 1988 to continue the incineration of dioxin-contaminated materials from sites in southwestern Missouri. This was the first application of an oxygen burner in a hazardous waste incineration system. The microprocessor-based controls of the oxygen system have exhibited excellent response, reducing the number of feed shutdowns due to low oxygen and high carbon monoxide contents in the stack gas which resulted from variations in the BTU content of the waste feed. It was also shown that nitrogen oxides emissions from the oxygen enriched operation compare favorably with the previous air-based operation.

  8. Results of Hazardous and Mixed Waste Excavation from the Chemical Waste Landfill

    SciTech Connect (OSTI)

    Young, S. G.; Schofield, D. P.; Kwiecinski, D.; Edgmon, C. L.; Methvin, R.

    2002-02-27T23:59:59.000Z

    This paper describes the results of the excavation of a 1.9-acre hazardous and mixed waste landfill operated for 23 years at Sandia National Laboratories, Albuquerque, New Mexico. Excavation of the landfill was completed in 2 1/2 years without a single serious accident or injury. Approximately 50,000 cubic yards of soil contaminated with volatile and semi-volatile organics, metals, polychlorinated biphenyl compounds, and radioactive constituents was removed. In addition, over 400 cubic yards of buried debris was removed, including bulk debris, unknown chemicals, compressed gas cylinders, thermal and chemical batteries, explosive and ordnance debris, pyrophoric materials and biohazardous waste. Removal of these wastes included negotiation of multiple regulations and guidances encompassed in the Resource Conservation and Recovery Act (RCRA), the Toxic Substances Control Act (TSCA), and risk assessment methodology. RCRA concepts that were addressed include the area of contamination, permit modification, emergency treatment provision, and listed waste designation. These regulatory decisions enabled the project to overcome logistical and programmatic needs such as increased operational area, the ability to implement process improvements while maintaining a record of decisions and approvals.

  9. Federal Environmental Permitting Handbook. Environmental Guidance

    SciTech Connect (OSTI)

    Not Available

    1991-05-01T23:59:59.000Z

    The handbook consists of eight chapters addressing permitting and licensing requirements under the Resource Conservation and Recovery Act (RCRA), the Comprehensive Environmental Response, Compensation, and Liability Act of 1980, as amended by the Superfund Amendments and Reauthorization Act of 1986 (CERCLA/SARA), the Atomic Energy Act (AEA), the Clean Air Act (CAA), the Clean Water Act (CWA), the Federal Insectide, Fungicide, and Rodenticide Act (FIFRA), the Safe Drinking Water Act (SDWA), and the Toxic Substances Control Act (TSCA). Each chapter consists of: (1) an introduction to the statute and permitting requirements; (2) a diagram illustrating the relationship between permitting requirements under the statute being discussed and permitting requirements from other environmental statutes which may have to be addressed when applying for a particular permit (e.g., when applying for a RCRA permit, permits and permit applications under the CWA, CAA, SDWA, etc. would have to be listed in the RCRA permit application); and, (3) a compilation of the permitting requirements for the regulatory program resulting from the statute. In addition, the Handbook contains a permitting keyword index and a listing of hotline telephone numbers for each of the statutes.

  10. Toxic chemical considerations for tank farm releases. Revision 1

    SciTech Connect (OSTI)

    Van Keuren, J.C.

    1995-11-01T23:59:59.000Z

    This document provides a method of determining the toxicological consequences of accidental releases from Hanford Tank Farms. A determination was made of the most restrictive toxic chemicals that are expected to be present in the tanks. Concentrations were estimated based on the maximum sample data for each analyte in all the tanks in the composite. Composite evaluated were liquids and solids from single shell tanks, double shell tanks, flammable gas watch list tanks, as well as all solids, all liquids, head space gases, and 241-C-106 solids. A sum of fractions of the health effects was computed for each composite for unit releases based emergency response planning guidelines (ERPGs). Where ERPGs were not available for chemical compounds of interest, surrogate guidelines were established. The calculation method in this report can be applied to actual release scenarios by multiplying the sum of fractions by the release rate for continuous releases, or the release amount for puff releases. Risk guidelines are met if the product is less than for equal to one.

  11. Physicochemical properties and toxicities of hydrophobicpiperidinium and pyrrolidinium ionic liquids

    SciTech Connect (OSTI)

    Salminen, Justin; Papaiconomou, Nicolas; Kumar, R. Anand; Lee,Jong-Min; Kerr, John; Newman, John; Prausnitz, John M.

    2007-06-25T23:59:59.000Z

    Some properties are reported for hydrophobic ionic liquids (IL) containing 1-methyl-1-propyl pyrrolidinium [MPPyrro]{sup +}, 1-methyl-1-butyl pyrrolidinium [MBPyrro]{sup +}, 1-methyl-1-propyl piperidinium [MPPip]{sup +}, 1-methyl-1-butyl piperidinium [MBPip]{sup +}, 1-methyl-1-octylpyrrolidinium [MOPyrro]{sup +} and 1-methyl-1-octylpiperidinium [MOPip]{sup +} cations. These liquids provide new alternatives to pyridinium and imidazolium ILs. High thermal stability of an ionic liquid increases safety in applications like rechargeable lithium-ion batteries and other electrochemical devices. Thermal properties, ionic conductivities, viscosities, and mutual solubilities with water are reported. In addition, toxicities of selected ionic liquids have been measured using a human cancer cell-line. The ILs studied here are sparingly soluble in water but hygroscopic. We show some structure-property relationships that may help to design green solvents for specific applications. While ionic liquids are claimed to be environmentally-benign solvents, as yet few data have been published to support these claims.

  12. The toxicity of Nerium oleander in the monkey (Cebus apella): a pathologic study

    E-Print Network [OSTI]

    Schwartz, William Lewis

    1970-01-01T23:59:59.000Z

    of chewing the flowers. Oleander produces dermatitis in 5, 11 certain humans upon contact with the skin ' Spontaneous and experimental oleander toxicity has been reported in many species 5, 8, 11, 30)36, 49, 53 . 11 7, 9, 11, 49 including humans... of Department Member (Member) August 1970 ABSTRACT The Toxicity of Nerium oleander in the Monkey (Cebus ~a ella): A Pathologic Study (August 1970) William Lewis Schwartz, B Sc , D. V M. The Ohio State Vniversity Directed by: Dr. W. W- Bay The toxic...

  13. Quantum Otto heat engine based on a multiferroic chain working substance

    E-Print Network [OSTI]

    Maryam Azimi; Levan Chotorlishvili; Sunil K. Mishra; Temo Vekua; Wolfgang Hübner; Jamal Berakdar

    2014-05-19T23:59:59.000Z

    We study a quantum Otto engine operating on the basis of a helical spin- 1/2 multiferroic chain with strongly coupled magnetic and ferroelectric order parameters. The presence of a finite spin chirality in the working substance enables steering of the cycle by an external electric field that couples to the electric polarization. We observe a direct connection between the chirality, the entanglement and the efficiency of the engine. An electric-field dependent threshold temperature is identified above which the pair correlations in the system, as quantified by the thermal entanglement, diminish. In contrast to the pair correlations, the collective many-body thermal entanglement is less sensitive to the electric field, and in the high temperature limit converges to a constant value. We also discuss the correlations between the threshold temperature of the pair entanglement, the spin chirality and the minimum of the fidelities in relation to the electric and magnetic fields. The efficiency of the quantum Otto cycle shows a saturation plateau with increasing electric field amplitude.

  14. Advances in associated-particle sealed-tube neutron probe diagnostics for substance detection

    SciTech Connect (OSTI)

    Rhodes, E.; Dickerman, C.E. [Argonne National Lab., IL (United States); Frey, M. [MF Physics Corp., Colorado Springs, CO (United States)

    1995-07-01T23:59:59.000Z

    The development and investigation of a small associated-particle sealed-tube neutron generator (APSTNG) shows potential to allow the associated-particle diagnostic method to be moved out of the laboratory into field applications. The APSTNG interrogates the inspected object with 14-MeV neutrons generated from the deuterium-tritium reaction and detects the alpha-particle associated with each neutron inside a cone encompassing the region of interest. Gamma-ray spectra of resulting neutron reactions identify many nuclides. Flight-times determined from detection times of the gamma-rays and alpha-particles can yield a separate coarse tomographic image of each identified nuclide, from a single orientation. Chemical substances are identified by comparing relative spectral line intensities with ratios of elements in reference compounds. The high-energy neutrons and gamma-rays penetrate large objects and dense materials. Generally no collimators or radiation shielding are needed. Proof-of-concept laboratory experiments have been successfully performed for simulated nuclear, chemical warfare, and conventional munitions. Most recently, inspection applications have been investigated for radioactive waste characterization, presence of cocaine in propane tanks, and uranium and plutonium smuggling. Based on lessons learned with the present APSTNG system, an advanced APSTNG tube (along with improved high voltage supply and control units) is being designed and fabricated that will be transportable and rugged, yield a substantial neutron output increase, and provide sufficiently improved lifetime to allow operation at more than an order of magnitude increase in neutron flux.

  15. Apparatus and methods for monitoring the concentrations of hazardous airborne substances, especially lead

    DOE Patents [OSTI]

    Zaromb, Solomon

    2004-07-13T23:59:59.000Z

    Air is sampled at a rate in excess of 100 L/min, preferably at 200-300 L/min, so as to collect therefrom a substantial fraction, i.e., at least 20%, preferably 60-100%, of airborne particulates. A substance of interest (analyte), such as lead, is rapidly solubilized from the the collected particulates into a sample of liquid extractant, and the concentration of the analyte in the extractant sample is determined. The high-rate air sampling and particulate collection may be effected with a high-throughput filter cartridge or with a recently developed portable high-throughput liquid-absorption air sampler. Rapid solubilization of lead is achieved by a liquid extractant comprising 0.1-1 M of acetic acid or acetate, preferably at a pH of 5 or less and preferably with inclusion of 1-10% of hydrogen peroxide. Rapid determination of the lead content in the liquid extractant may be effected with a colorimetric or an electroanalytical analyzer.

  16. Evaluation and analysis of non-intrusive techniques for detecting illicit substances

    SciTech Connect (OSTI)

    Micklich, B.J.; Roche, C.T.; Fink, C.L.; Yule, T.J.; Demirgian, J.C. [Argonne National Lab., IL (United States); Kunz, T.D.; Ulvick, S.J.; Cui, J. [Houston Advanced Research Center, The Woodlands, TX (United States)

    1995-12-31T23:59:59.000Z

    Argonne National Laboratory (ANL) and the Houston Advanced Research Center (HARC) have been tasked by the Counterdrug Technology Assessment Center of the Office of National Drug Control Policy to conduct evaluations and analyses of technologies for the non-intrusive inspection of containers for illicit substances. These technologies span the range of nuclear, X-ray, and chemical techniques used in nondestructive sample analysis. ANL has performed assessments of nuclear and X-ray inspection concepts and undertaken site visits with developers to understand the capabilities and the range of applicability of candidate systems. ANL and HARC have provided support to law enforcement agencies (LEAs), including participation in numerous field studies. Both labs have provided staff to assist in the Narcotics Detection Technology Assessment (NDTA) program for evaluating drug detection systems. Also, the two labs are performing studies of drug contamination of currency. HARC has directed technical evaluations of automated ballistics imaging and identification systems under consideration by law enforcement agencies. ANL and HARC have sponsored workshops and a symposium, and are participating in a Non-Intrusive Inspection Study being led by Dynamics Technology, Incorporated.

  17. Do-Not-Resuscitate Orders in Fatal Toxic Exposures: A Poison Center’s Review

    E-Print Network [OSTI]

    Weerasuriya, Dilani; Sheikh, Sophia; Morgan, Brent W

    2012-01-01T23:59:59.000Z

    in Fatal Toxic Exposures: A Poison Center’s Review DilaniAtlanta, Georgia Georgia Poison Control, Atlanta, GeorgiaISE) patient using the Regional Poison Control Center (RPCC)

  18. Leaching and toxicity behavior of coal-biomass waste cocombustion ashes

    SciTech Connect (OSTI)

    Skodras, G.; Prokopidou, M.; Sakellaropoulos, G.P. [Aristotle University in Thessaloniki, Thessaloniki (Greece). Dept. for Chemical Engineering

    2006-08-15T23:59:59.000Z

    Land disposal of ash residues, obtained from the cocombustion of Greek lignite with biomass wastes, is known to create problems due to the harmful constituents present. In this regard, the leachability of trace elements from lignite, biomass, and blends cocombustion ashes was investigated by using the Toxicity Characteristic Leaching Procedure (TCLP) of the US Environmental Protection Agency (US EPA). In this work, the toxicity of the aqueous leachates and the concentrations of the metals obtained from the leaching procedure were measured using the Microtox test (Vibrio fischen) and inductive coupled plasma-atomic emission spectrometer (ICP-AES), respectively. The toxic effects of most leachates on Vibrio fischeri were found to be significantly low in both 45% and 82% screening test protocols. However, the liquid sample originating from olive kernels fly ash (FA4) caused the highest toxic effect in both protocols, which can be attributed to its relatively high concentrations of As, Cd, Co, Cu, Mn, Ni, and Zn.

  19. Compatibility and toxicity of polymer-coated magnetic nanoparticles on mammalian cell systems

    E-Print Network [OSTI]

    Kral, Kelly M., 1979-

    2005-01-01T23:59:59.000Z

    (cont.) produced normal growth curves in the presence of particles. However, the particles do still exhibit some toxicity towards the cells, as the maximum cell density of cells cultured with particles does not reach that ...

  20. Toxicity of oiled wetland sediments influenced by natural and enhanced bioremediation

    E-Print Network [OSTI]

    Mueller, Danica Christine

    1998-01-01T23:59:59.000Z

    Gene System (RGS), Toxi-ChromoPad and Salmonella/microsome assays. Significant toxicity was detected (Microtox*) in all plots that were oiled followed by a rapid decrease that was correlated to petroleum losses. Amphipod mortality was initially high...

  1. Application of novel methods using synthetic biology tools to investigate solvent toxicity in bacteria 

    E-Print Network [OSTI]

    Fletcher, Eugene Kobina Arhin

    2014-06-28T23:59:59.000Z

    Toxicity of organic solvents to microbial hosts is a major consideration in the economical production of biofuels such as ethanol and especially butanol, with low product concentrations leading to high recovery costs. ...

  2. Molecules and materials for the optical detection of explosives and toxic chemicals

    E-Print Network [OSTI]

    Thomas, Samuel William, III

    2006-01-01T23:59:59.000Z

    Optical chemosensing, especially using amplifying fluorescent polymers, can allow for the highly sensitive and selective vapor-phase detection of both explosives and highly toxic chemicals, including chemical warfare agents. ...

  3. Emissions of airborne toxics from coal-fired boilers: Mercury

    SciTech Connect (OSTI)

    Huang, H.S.; Livengood, C.D.; Zaromb, S.

    1991-09-01T23:59:59.000Z

    Concerns over emissions of hazardous air Pollutants (air toxics) have emerged as a major environmental issue, and the authority of the US Environmental Protection Agency to regulate such pollutants was greatly expanded through the Clean Air Act Amendments of 1990. Mercury has been singled out for particular attention because of concerns over possible effects of emissions on human health. This report evaluates available published information on the mercury content of coals mined in the United States, on mercury emitted in coal combustion, and on the efficacy of various environmental control technologies for controlling airborne emissions. Anthracite and bituminous coals have the highest mean-mercury concentrations, with subbituminous coals having the lowest. However, all coal types show very significant variations in mercury concentrations. Mercury emissions from coal combustion are not well-characterized, particularly with regard to determination of specific mercury compounds. Variations in emission rates of more than an order of magnitude have been reported for some boiler types. Data on the capture of mercury by environmental control technologies are available primarily for systems with electrostatic precipitators, where removals of approximately 20% to over 50% have been reported. Reported removals for wet flue-gas-desulfurization systems range between 35 and 95%, while spray-dryer/fabric-filter systems have given removals of 75 to 99% on municipal incinerators. In all cases, better data are needed before any definitive judgments can be made. This report briefly reviews several areas of research that may lead to improvements in mercury control for existing flue-gas-clean-up technologies and summarizes the status of techniques for measuring mercury emissions from combustion sources.

  4. Proteomic analysis of rat cerebral cortex following subchronic acrolein toxicity

    SciTech Connect (OSTI)

    Rashedinia, Marzieh; Lari, Parisa [Department of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad (Iran, Islamic Republic of); Abnous, Khalil, E-mail: Abnouskh@mums.ac.r [Pharmaceutical Research Center, Department of Medicinal Chemistry, Mashhad University of Medical Sciences, Mashhad (Iran, Islamic Republic of); Hosseinzadeh, Hossein, E-mail: Hosseinzadehh@mums.ac.ir [Pharmaceutical Research Center, Department of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad (Iran, Islamic Republic of)

    2013-10-01T23:59:59.000Z

    Acrolein, a member of reactive ?,?-unsaturated aldehydes, is a major environmental pollutant. Acrolein is also produced endogenously as a toxic by-product of lipid peroxidation. Because of high reactivity, acrolein may mediate oxidative damages to cells and tissues. It has been shown to be involved in a wide variety of pathological states including pulmonary, atherosclerosis and neurodegenerative diseases. In this study we employed proteomics approach to investigate the effects of subchronic oral exposures to 3 mg/kg of acrolein on protein expression profile in the brain of rats. Moreover effects of acrolein on malondialdehyde (MDA) levels and reduced glutathione (GSH) content were investigated. Our results revealed that treatment with acrolein changed levels of several proteins in diverse physiological process including energy metabolism, cell communication and transport, response to stimulus and metabolic process. Interestingly, several differentially over-expressed proteins, including ?-synuclein, enolase and calcineurin, are known to be associated with human neurodegenerative diseases. Changes in the levels of some proteins were confirmed by Western blot. Moreover, acrolein increases the level of MDA, as a lipid peroxidation biomarker and decreased GSH concentrations, as a non-enzyme antioxidant in the brain of acrolein treated rats. These findings suggested that acrolein induces the oxidative stress and lipid peroxidation in the brain, and so that may contribute to the pathophysiology of neurological disorders. - Highlights: • Acrolein intoxication increased lipid peroxidation and deplete GSH in rat brain. • Effect of acrolein on protein levels of cerebral cortex was analyzed by 2DE-PAGE. • Levels of a number of proteins with different biological functions were increased.

  5. On using rational enzyme redesign to improve enzyme-mediated microbial dehalogenation of recalcitrant substances in deep-subsurface environments

    SciTech Connect (OSTI)

    Ornstein, R.L.

    1993-06-01T23:59:59.000Z

    Heavily halogenated hydrocarbons are one of the most prevalent classes of man-made recalcitrant environmental contaminants and often make their way into subsurface environments. Biodegradation of heavily chlorinated compounds in the deep subsurface often occurs at extremely slow rates because native enzymes of indigenous microbes are unable to efficiently metabolize such synthetic substances. Cost-effective engineering solutions do not exist for dealing with disperse and recalcitrant pollutants in the deep subsurface (i.e., ground water, soils, and sediments). Timely biodegradation of heavily chlorinated compounds in the deep subsurface may be best accomplished by rational redesign of appropriate enzymes that enhance the ability of indigenous microbes to metabolize these substances. The isozyme family cytochromes P450 are catalytically very robust and are found in all aerobic life forms and may be active in may anaerobes as well. The author is attempting to demonstrate proof-of-principle rational enzyme redesign of cytochromes P450 to enhance biodehalogenation.

  6. Toxic species emissions from controlled combustion of selected automotive rubber components 

    E-Print Network [OSTI]

    Shalkowski, Mark Henry

    1993-01-01T23:59:59.000Z

    TOXIC SPECIES EMISSIONS FROM CONTROLLED COMBUSTION OF SELECTED AUTOMOTIVE RUBBER COMPONENTS A Thesis by MARK HENRY SHALKOWSKI Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements... for the degree of MASTER OF SCIENCE August 1993 Major Subject: Safety Engineering TOXIC SPECIES EMISSIONS FROM CONTROLLED COMBUSTION OF SELECTED AUTOMOTIVE RUBBER COMPONENTS A Thesis by MARK HENRY SHALKOWSKI Approved as to style and content by: // John...

  7. Acute and chronic toxicity of municipal landfill leachate as determined with bioassays and chemical analysis

    E-Print Network [OSTI]

    Schrab, Gregory Ernst

    1990-01-01T23:59:59.000Z

    municipal landfill leachates were determined to have mean estimated cumulative cancer risks on the same order of magnitude (10 4) as leachates from co-disposal and hazardous waste landfills. The use of a battery of acute and chronic toxicity bioassays..., chemical analysis, and an estimated cancer risk calculation resulted in data providing evidence that municipal solid waste landfill leachates are as acutely and chronically toxic as co-disposal and hazardous waste landfill leachates. ACKNOWLEDGEMENTS...

  8. Critical elements in the design of piping systems for toxic fluids

    SciTech Connect (OSTI)

    Getz, R.C. [Raytheon Engineers and Constructors, Philadelphia, PA (United States)] [Raytheon Engineers and Constructors, Philadelphia, PA (United States)

    1996-09-01T23:59:59.000Z

    While releases of hazardous/toxic fluids from pressurized pipelines are infrequent, the potential for a catastrophic event resulting from such a release warrants extraordinary care of the hazardous/toxic piping systems containing these fluids, during the entire plant life cycle. System identification, segregation, material and component selection, construction techniques, and preventative maintenance programs all contribute to improved system reliability, and are discussed herein. Methods to mitigate damages in the event of a failure are also discussed.

  9. Comparative toxicity studies of sulphur acaricides on two species of spider mites attacking cotton

    E-Print Network [OSTI]

    Hallmark, Kenzy Donovan

    1954-01-01T23:59:59.000Z

    CONPARATIVE TOXICITY STUDIES OF SULFUH ACAHICIDES ON TWO SPECIE OF SPIDEH NITES ATTACKING COTTON KENZY DONOVAN HALLI&AHK A Thesis Submitted to the Graduate School oi' the Agricultural and 14echanlcal College of Texas in partial fulfillment... Ovotran- 13 Procedure Culturing technique- Dusting apparatus 1B 18 19 Spraying appsratus- Treatment procedure ?- Determination ef results ? - ? --- ? ? ? -?- hesults Conclusions- Literature Cited- 47 50 1 Results of laboratortJ' toxicity...

  10. The effect of climatic factors on the toxicity of certain organic insecticides

    E-Print Network [OSTI]

    Mistric, Walter Joseph

    1954-01-01T23:59:59.000Z

    THE EFFECT OF CLIMATIC FACTORS ON THE TOXICITY OF CERTAIN ORGANIC INSECTICIDES A Dissertation By MILTER JOSEPH MISTRIC, JR, Approved as to style and content by: (Chairman of Committee) ?7*(Head Df Department) May THEF L IB R A R Y A & M... COLLEGE OF TEXAS. THE EFFECT OF CLIMATIC FACTORS ON THE TOXICITY OF CERTAIN ORGANIC INSECTICIDES By HALTER JOSEPH MISTRIC, JR A Dissertation Submitted to the Graduate School of the Agricultural and Mechanical College of Texas in partial fulfillment...

  11. Developmental toxicity and structure-activity relationships of ochratoxin A and related compounds in Hydra attenuata

    E-Print Network [OSTI]

    Taylor, Monica Ann

    1988-01-01T23:59:59.000Z

    DEVELOPMENTAL TOXICITY AND STRUCTURE-ACTIVITY RELATIONSHIPS OF OCHRATOXIN A AND RELATED COMPOUNDS IN HYDRA ATTENUATA A Thesis by MONICA ANN TAYLOR Submitted to the Office of Graduate Studies of Texas ARM University in Partial fulfillment... of the requirements for the degree of MASTER OF SCIENCE December 1988 Major Subject: Food Science and Technology DEVELOPMENTAL TOXICITY AND STRUCTURE-ACTIVITY RELATIONSHIPS OF OCHRATOXIN A AND RELATED COMPOUNDS IN ~HY R ATTENUATA A Thesis by MONICA ANN TAYLOR...

  12. Comparative toxicity studies of sulphur acaricides on two species of spider mites attacking cotton 

    E-Print Network [OSTI]

    Hallmark, Kenzy Donovan

    1954-01-01T23:59:59.000Z

    CONPARATIVE TOXICITY STUDIES OF SULFUH ACAHICIDES ON TWO SPECIE OF SPIDEH NITES ATTACKING COTTON KENZY DONOVAN HALLI&AHK A Thesis Submitted to the Graduate School oi' the Agricultural and 14echanlcal College of Texas in partial fulfillment... Ovotran- 13 Procedure Culturing technique- Dusting apparatus 1B 18 19 Spraying appsratus- Treatment procedure ?- Determination ef results ? - ? --- ? ? ? -?- hesults Conclusions- Literature Cited- 47 50 1 Results of laboratortJ' toxicity...

  13. The effect of climatic factors on the toxicity of certain organic insecticides 

    E-Print Network [OSTI]

    Mistric, Walter Joseph

    1954-01-01T23:59:59.000Z

    THE EFFECT OF CLIMATIC FACTORS ON THE TOXICITY OF CERTAIN ORGANIC INSECTICIDES A Dissertation By MILTER JOSEPH MISTRIC, JR, Approved as to style and content by: (Chairman of Committee) ?7*(Head Df Department) May THEF L IB R A R Y A & M... COLLEGE OF TEXAS. THE EFFECT OF CLIMATIC FACTORS ON THE TOXICITY OF CERTAIN ORGANIC INSECTICIDES By HALTER JOSEPH MISTRIC, JR A Dissertation Submitted to the Graduate School of the Agricultural and Mechanical College of Texas in partial fulfillment...

  14. Developmental toxicity and structure-activity relationships of ochratoxin A and related compounds in Hydra attenuata 

    E-Print Network [OSTI]

    Taylor, Monica Ann

    1988-01-01T23:59:59.000Z

    DEVELOPMENTAL TOXICITY AND STRUCTURE-ACTIVITY RELATIONSHIPS OF OCHRATOXIN A AND RELATED COMPOUNDS IN HYDRA ATTENUATA A Thesis by MONICA ANN TAYLOR Submitted to the Office of Graduate Studies of Texas ARM University in Partial fulfillment... of the requirements for the degree of MASTER OF SCIENCE December 1988 Major Subject: Food Science and Technology DEVELOPMENTAL TOXICITY AND STRUCTURE-ACTIVITY RELATIONSHIPS OF OCHRATOXIN A AND RELATED COMPOUNDS IN ~HY R ATTENUATA A Thesis by MONICA ANN TAYLOR...

  15. Toxicity of ammonia to larvae of the freshwater shrimp, Macrobrachium rosenbergii 

    E-Print Network [OSTI]

    Llobrera, Jose Alvarez

    1979-01-01T23:59:59.000Z

    TOXICITY OF AMMONIA TO LARVAE OF THE FRESHWATER SHRIMP, MACR OBRACHIUM R OSENBERGI I A Thesis by JOSE ALVAREZ LLOBRERA Submitted to the Graduate College of Texas ARM University in partial fulfillment of the requirement for the degree... of MASTER OF SCIENCE May 1979 Major Subject: Wildlife and Fisheries Sciences TOXICITY OF AMMONIA TO LARVAE OF THE FRESHWATER SHRIMP, MACR OBRACHIUM ROSENBERGI I A Thesis JOSE ALVAREZ LLOBRERA Approved as to style and content by: (Chairman...

  16. Acute and chronic toxicity of municipal landfill leachate as determined with bioassays and chemical analysis 

    E-Print Network [OSTI]

    Schrab, Gregory Ernst

    1990-01-01T23:59:59.000Z

    ACUTE AND CHRONIC TOXICITY OF MUNICIPAL LANDFILL LEACHATE AS DETERMINED WITH BIOASSAYS AND CHEMICAL ANALYSIS A Thesis by GREGORY ERNST SCHRAB Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment... of the requirements for the degree of MASTER OF SCIENCE May 1990 Major Subject: Soil Science ACUTF AND CHRONIC TOXICITY OF MUNICIPAL LANDFILL LEACHATE AS DETERMINED WITH BIOASSAYS AND CHEMICAL ANALYSIS A Thesis by GREGORY ERNST SCHRAB Approved as to style...

  17. Investigation of measuring hazardous substances in printed circuit boards using the micro-focus X-ray fluorescence screening

    E-Print Network [OSTI]

    Fu, M L; Fakhrtdinov, R; Grigoriev, M; Quan, B S; Le, Z C; Roshchupkin, D

    2014-01-01T23:59:59.000Z

    Printed circuit boards (PCBs) are widely used in most electrical and electronic equipments or products. Hazardous substances such as Pb, Hg, Cd, etc, can be present in high concentrations in PCBs and the degradation and release of these substances poses a huge threat to humans and the environment. To investigation the chemical composition of PCBs in domestic market of China, a practical micro-focus X-ray fluorescence system is setup to make the elements analysis, especially for detecting hazardous substances. Collimator is adopted to focus the X-ray emitted from X-ray tube. BRUKER X-ray detector with proportional counter is used to detect the emitted fluorescence from the PCB samples. Both single layer PCB samples and double layers PCB samples made of epoxy glass fiber are purchased from the domestic market of China. Besides, a MC55 wireless communication module made by SIEMENS in Germany is used as the reference material. Experimental results from the fluorescence spectrums of the testing points of PCB sampl...

  18. ULTRA HIGH EFFICIENCY ESP DEVELOPMENT FOR AIR TOXICS CONTROL

    SciTech Connect (OSTI)

    David K. Anderson

    1999-11-01T23:59:59.000Z

    Because more than 90 percent of U.S. coal-fired utility boilers are equipped with electrostatic precipitators (ESPs), retrofitable ESP technologies represent a logical approach towards achieving the Department of Energy's (DOE) goal of a major reduction in fine particulate and mercury emissions (air toxics) from coal based power systems. EPA's recent issuance of significantly tightened ambient air standards for particles smaller than 2.5 {micro}m (PM{sub 2.5}) creates a new urgency for developing cost-effective means to control fine particulate emissions. This challenge is compounded by the on-going switch in the utility industry to low-sulfur Powder River Basin (PRB) coals, that generate higher resistivity and difficult-to-collect fly ash. Particulate emissions can increase by a factor of ten when a utility switches to a low-sulfur coal. Numerous power plants are presently limited in operation by the inability of their ESPs to control opacity at high loads. In Phase I of this program, ABB investigated five technologies to improve the collection of fine particulate and trace metals in ESPs. These included: (1) flue-gas cooling, (2) flue-gas humidification, (3) pulsed energization, (4) wet ESP and precharger modules, and (5) sorbent injection for mercury control. Tests were conducted with an Eastern bituminous coal and a Powder River Basin sub-bituminous low-sulfur coal in an integrated pilot-scale combustor and ESP test facility. The impacts of the different retrofit technologies on ESP performance, individually and in combination, were evaluated indepth through advanced sampling and measurement techniques. In Phase II, the most promising concepts identified from Phase I testing, flue-gas cooling and humidification, pulsed energization, and sorbent injection at low flue-gas temperatures for mercury control, were integrated into a commercially oriented sub-scale system for field testing at Commonwealth Edison's Waukegan Unit No. 8. The main objective of the proposed Phase II testing was to determine longer term ESP performance and mercury capture improvements with the above enhancements for a range of low-sulfur coals currently fired by utilities. Unanticipated cost growth in readying the Pilot Plant for shipment and during slipstream construction at the utility host site resulted in the issuance of a preemptive stop work order from ABB until a detailed technical and budgetary review of the project could be completed. Four program recovery scenarios were developed and presented to the DOE. After careful review of these options, it was decided to terminate the program and although the Pilot Plant installation was essentially completed, no testing was performed. The Pilot Plant was subsequently decommissioned and the host site returned to its preprogram condition.

  19. 2008 Toxic Chemical Release Inventory 2008 Toxic Chemical Release Inventory Community Right-to-Know Act of 1986, Title III, Section 313

    SciTech Connect (OSTI)

    Ecology and Air Quality Group

    2009-10-01T23:59:59.000Z

    For reporting year 2008, Los Alamos National Laboratory (LANL) submitted a Form R report for lead as required under the Emergency Planning and Community Right-to- Know Act (EPCRA) Section 313. No other EPCRA Section 313 chemicals were used in 2008 above the reportable thresholds. This document was prepared to provide a description of the evaluation of EPCRA Section 313 chemical use and threshold determinations for LANL for calendar year 2008, as well as to provide background information about data included on the Form R reports. Section 313 of EPCRA specifically requires facilities to submit a Toxic Chemical Release Inventory Report (Form R) to the U.S. Environmental Protection Agency (EPA) and state agencies if the owners and operators manufacture, process, or otherwise use any of the listed toxic chemicals above listed threshold quantities. EPA compiles this data in the Toxic Release Inventory database. Form R reports for each chemical over threshold quantities must be submitted on or before July 1 each year and must cover activities that occurred at the facility during the previous year. In 1999, EPA promulgated a final rule on persistent bioaccumulative toxics (PBTs). This rule added several chemicals to the EPCRA Section 313 list of toxic chemicals and established lower reporting thresholds for these and other PBT chemicals that were already reportable. These lower thresholds became applicable in reporting year 2000. In 2001, EPA expanded the PBT rule to include a lower reporting threshold for lead and lead compounds. Facilities that manufacture, process, or otherwise use more than 100 lb of lead or lead compounds must submit a Form R.

  20. A study of toxic emissions from a coal-fired power plant utilizing the SNOX innovative clean coal technology demonstration. Volume 1, Sampling/results/special topics: Final report

    SciTech Connect (OSTI)

    Not Available

    1994-07-01T23:59:59.000Z

    This study was one of a group of assessments of toxic emissions from coal-fired power plants, conducted for DOE during 1993. The motivation for those assessments was the mandate in the 1990 Clean Air Act Amendments that a study be made of emissions of hazardous air pollutants (HAPs) from electric utilities. The report is organized in two volumes. Volume 1: Sampling describes the sampling effort conducted as the basis for this study; Results presents the concentration data on HAPs in the several power plant streams, and reports the results of evaluations and calculations conducted with those data; and Special Topics report on issues such as comparison of sampling methods and vapor/solid distributions of HAPs. Volume 2: Appendices include quality assurance/quality control results, uncertainty analysis for emission factors, and data sheets. This study involved measurements of a variety of substances in solid, liquid, and gaseous samples from input, output, and process streams at the Innovative Clean Coal Technology Demonstration (ICCT) of the Wet Sulfuric Acid-Selective Catalytic Reduction (SNOX) process. The SNOX demonstration is being conducted at Ohio Edison`s Niles Boiler No. 2 which uses cyclone burners to burn bituminous coal. A 35 megawatt slipstream of flue gas from the boiler is used to demonstrate SNOX. The substances measured at the SNOX process were the following: 1. Five major and 16 trace elements, including mercury, chromium, cadmium, lead, selenium, arsenic, beryllium, and nickel; 2. Acids and corresponding anions (HCl, HF, chloride, fluoride, phosphate, sulfate); 3. Ammonia and cyanide; 4. Elemental carbon; 5. Radionuclides; 6. Volatile organic compounds (VOC); 7. Semi-volatile compounds (SVOC) including polynuclear aromatic hydrocarbons (PAH); and 8. Aldehydes.

  1. Method of in situ retrieval of contaminants or other substances using a barrier system and leaching solutions

    DOE Patents [OSTI]

    Nickelson, Reva A.; Walsh, Stephanie; Richardson, John G.; Dick, John R.; Sloan, Paul A.

    2006-12-26T23:59:59.000Z

    Processes and methods relating to treating contaminants and collecting desired substances from a zone of interest using subterranean collection and containment barriers. Tubular casings having interlock structures are used to create subterranean barriers for containing and treating buried waste and its effluents. The subterranean barrier includes an effluent collection system. Treatment solutions provided to the zone of interest pass therethrough and are collected by the barrier and treated or recovered, allowing on-site remediation. Barrier components may be used to in the treatment by collecting or removing contaminants or other materials from the zone of interest.

  2. Reduced Acute Bowel Toxicity in Patients Treated With Intensity-Modulated Radiotherapy for Rectal Cancer

    SciTech Connect (OSTI)

    Samuelian, Jason M. [Department of Radiation Oncology, Mayo Clinic, Scottsdale, AZ (United States); Callister, Matthew D., E-mail: Callister.matthew@mayo.edu [Department of Radiation Oncology, Mayo Clinic, Scottsdale, AZ (United States); Ashman, Jonathan B. [Department of Radiation Oncology, Mayo Clinic, Scottsdale, AZ (United States); Young-Fadok, Tonia M. [Division of Colorectal Surgery, Mayo Clinic, Scottsdale, AZ (United States); Borad, Mitesh J. [Division of Hematology-Oncology, Mayo Clinic, Scottsdale, AZ (United States); Gunderson, Leonard L. [Department of Radiation Oncology, Mayo Clinic, Scottsdale, AZ (United States)

    2012-04-01T23:59:59.000Z

    Purpose: We have previously shown that intensity-modulated radiotherapy (IMRT) can reduce dose to small bowel, bladder, and bone marrow compared with three-field conventional radiotherapy (CRT) technique in the treatment of rectal cancer. The purpose of this study was to review our experience using IMRT to treat rectal cancer and report patient clinical outcomes. Methods and Materials: A retrospective review was conducted of patients with rectal cancer who were treated at Mayo Clinic Arizona with pelvic radiotherapy (RT). Data regarding patient and tumor characteristics, treatment, acute toxicity according to the Common Terminology Criteria for Adverse Events v 3.0, tumor response, and perioperative morbidity were collected. Results: From 2004 to August 2009, 92 consecutive patients were treated. Sixty-one (66%) patients were treated with CRT, and 31 (34%) patients were treated with IMRT. All but 2 patients received concurrent chemotherapy. There was no significant difference in median dose (50.4 Gy, CRT; 50 Gy, IMRT), preoperative vs. postoperative treatment, type of concurrent chemotherapy, or history of previous pelvic RT between the CRT and IMRT patient groups. Patients who received IMRT had significantly less gastrointestinal (GI) toxicity. Sixty-two percent of patients undergoing CRT experienced {>=}Grade 2 acute GI side effects, compared with 32% among IMRT patients (p = 0.006). The reduction in overall GI toxicity was attributable to fewer symptoms from the lower GI tract. Among CRT patients, {>=}Grade 2 diarrhea and enteritis was experienced among 48% and 30% of patients, respectively, compared with 23% (p = 0.02) and 10% (p = 0.015) among IMRT patients. There was no significant difference in hematologic or genitourinary acute toxicity between groups. In addition, pathologic complete response rates and postoperative morbidity between treatment groups did not differ significantly. Conclusions: In the management of rectal cancer, IMRT is associated with a clinically significant reduction in lower GI toxicity compared with CRT. Further study is needed to evaluate differences in late toxicity and long-term efficacy.

  3. Biological treatment of concentrated hazardous, toxic, andradionuclide mixed wastes without dilution

    SciTech Connect (OSTI)

    Stringfellow, William T.; Komada, Tatsuyuki; Chang, Li-Yang

    2004-06-15T23:59:59.000Z

    Approximately 10 percent of all radioactive wastes produced in the U. S. are mixed with hazardous or toxic chemicals and therefore can not be placed in secure land disposal facilities. Mixed wastes containing hazardous organic chemicals are often incinerated, but volatile radioactive elements are released directly into the biosphere. Some mixed wastes do not currently have any identified disposal option and are stored locally awaiting new developments. Biological treatment has been proposed as a potentially safer alternative to incineration for the treatment of hazardous organic mixed wastes, since biological treatment would not release volatile radioisotopes and the residual low-level radioactive waste would no longer be restricted from land disposal. Prior studies have shown that toxicity associated with acetonitrile is a significant limiting factor for the application of biotreatment to mixed wastes and excessive dilution was required to avoid inhibition of biological treatment. In this study, we demonstrate that a novel reactor configuration, where the concentrated toxic waste is drip-fed into a complete-mix bioreactor containing a pre-concentrated active microbial population, can be used to treat a surrogate acetonitrile mixed waste stream without excessive dilution. Using a drip-feed bioreactor, we were able to treat a 90,000 mg/L acetonitrile solution to less than 0.1 mg/L final concentration using a dilution factor of only 3.4. It was determined that the acetonitrile degradation reaction was inhibited at a pH above 7.2 and that the reactor could be modeled using conventional kinetic and mass balance approaches. Using a drip-feed reactor configuration addresses a major limiting factor (toxic inhibition) for the biological treatment of toxic, hazardous, or radioactive mixed wastes and suggests that drip-feed bioreactors could be used to treat other concentrated toxic waste streams, such as chemical warfare materiel.

  4. 1997 toxic chemical release inventory -- Emergency Planning and Community Right-To-Know Act, Section 313

    SciTech Connect (OSTI)

    Zaloudek, D.E.

    1998-06-30T23:59:59.000Z

    Two listed toxic chemicals were used at the Hanford Site above established activity thresholds: phosphoric acid and chlorine. Because total combined quantities of chlorine released, disposed, treated, recovered through recycle operations, co-combusted for energy recovery, and transferred to off-site locations for the purpose of recycle, energy recovery, treatment, and/or disposal, amounted to less than 500 pounds, the Hanford Site qualified for the alternate one million pound threshold for chlorine. Accordingly, this Toxic Chemical Release Inventory includes a Form A for chlorine, and a Form B for phosphoric acid.

  5. The Toxicity of the Ripe Fruit of Blackbrush or Tarbrush (Flourensia cernua) for Sheep and Goats.

    E-Print Network [OSTI]

    Mathews, F. P. (Frank Patrick)

    1944-01-01T23:59:59.000Z

    to the plant. When sheep and goats have continuous access to the plant and are not subjected to-handling during the winter months,there is no evidence that this p&k'of the ~lant is grazed in sufficient amounts to cause toxic effects. The plant has not been... associated with similar losses in cattle. 1 The toxicity of the ripe fruit was demonstrated by experimental i feeding to sheep and goats. o In this wark a marked variation in the ~ueceptihility of different iddividuals was observed, as well as a nar...

  6. Comparison of stomach and contact toxicities of toxaphene and guthion to two species of lepidopterous larvae

    E-Print Network [OSTI]

    Martin, Hugo Danilo

    1957-01-01T23:59:59.000Z

    COMPARISON GF STOMACH AND CONTACT TOXICITIES OF TOXAPHENE AND GKH ION By HUGO D. MARTIN A Thesis Submitted to the Graduate School of the Agricultural and Mechanical College of T!sxas in partial fulfillment of the requirements for the degree... of MASTER GF SCIENCE May 1957 Ms/or Sub)cot: ENTOMOLOGY COMPARISON GF STOMACH AND CONTACT TOXICITIES OF TO~ AND GUTHIGN TNO SPECIES OF LEPROUS LARVAE HUGO D. MARTIN Approved as to style and content by: irjasn of Committee ead o the Department lhe...

  7. Potential hazards of compound 1080 to selected nontarget wildlife when used in the toxic collar

    E-Print Network [OSTI]

    Eastland, Warren George

    1983-01-01T23:59:59.000Z

    POTENTIAL NA7ARDS OF COMPOUND 1080 TO SELECTED NONTARGET WI~ DLIFE WHEN USED IN TliE TOXIC COLLAR A Thesis by WARREN GEORGE EASTLAND Submitted to the Graduate College of Texas AfM University in partial fulfillment of the requirement... for the degree of MASTER OF SCIENCE August 1983 Major Subject: Wild'life and Fisheries Sciences POTENTIAL HAZARDS OF COMPOUND 1080 TO SELECTED NONTARGET WILDLIFE WHEN USED IN THE TOXIC COLLAR A Thesis by WARREN GEORGE EASTLAND Approved as to style...

  8. The toxic levels of Microcide, a chlorine compound, for selected fishes

    E-Print Network [OSTI]

    Champ, Michael Augustus

    1969-01-01T23:59:59.000Z

    THE TOXIC LEVELS OF M)CROCIDE, A CHLORINE COMPOUND, FOR SELECTED FISHES A Thesis by Michael A. Champ Submitted to the Graduate College of Texas A=M University in partial fultillment of the requirement for the degree of MASTER OF SCIENCE May... !9S9 Majot Subject; Biology THE TOXIC LEVELS OF MICROCIDE, A CHLORIHE COMPOUND, FOR SELECTED FISHES A Thesis by MICHAEL A. CHAMP Approved as to style and content by: Ciairman of mmittee (Member j (He~mb r May 1&6& n ~~. n E&r;~ri ABSTRACT...

  9. Toxicity of polychlorinated diphenyl ethers in Hydra attenuata and in rat whole embryo culture

    E-Print Network [OSTI]

    Becker, Marion Carol

    1991-01-01T23:59:59.000Z

    TOXICITY OF POLYCHLORINATED DIPHENYL ETHERS IN HYDRA A?TENUATA AND IN RAT WHOLE EMBRYO CULTURE A Thesis by MARION CAROL BECKER Submitted to the Office of Graduate Studies of Texas A8cM University in partial fulfillment of the requirements... for the degree of MASTER OF SCIENCE May 1991 Major Subject: Toxicology TOXICITY OF POLYCHLORINATED DIPHENYL ETHERS IN HYDRA A1TENUATA AND IN RAT WHOLE EMBRYO CULTURE by MARION CAROL BECKER Approved as to style and content by: Stephen H. S (Ca...

  10. Toxicity of polychlorinated diphenyl ethers in Hydra attenuata and in rat whole embryo culture 

    E-Print Network [OSTI]

    Becker, Marion Carol

    1991-01-01T23:59:59.000Z

    TOXICITY OF POLYCHLORINATED DIPHENYL ETHERS IN HYDRA A?TENUATA AND IN RAT WHOLE EMBRYO CULTURE A Thesis by MARION CAROL BECKER Submitted to the Office of Graduate Studies of Texas A8cM University in partial fulfillment of the requirements... for the degree of MASTER OF SCIENCE May 1991 Major Subject: Toxicology TOXICITY OF POLYCHLORINATED DIPHENYL ETHERS IN HYDRA A1TENUATA AND IN RAT WHOLE EMBRYO CULTURE by MARION CAROL BECKER Approved as to style and content by: Stephen H. S (Ca...

  11. Detection of toxic factors after gamma-irradiation in vitro and in vivo 

    E-Print Network [OSTI]

    Shihabi, Zakariya Kamel

    1965-01-01T23:59:59.000Z

    DETECTION QF TOXIC FACTORS AFTER GAMMA-IRRADIATION ~ V~IO AND IN VIVO A Thesis By Zaksriya K. Shihabi Submitted to the Graduate College of the Texas A & M University in partial fulfillment of the requirements for the degree of MASTER... OF SCIENCE January 1965 Major Subject: Biochemistry snd Nutrition DETECTIOE OF TOXIC FACTORS AFTER GAMMA-IRRADIATIOE gf. ~ AND g[ ~ By Zakariya K. Shihabi Approved as to ~le and content by& 8 j &"';Dr j J j R~ Couch . G. N i. se Dr. M. L r. C. R...

  12. Comparison of stomach and contact toxicities of toxaphene and guthion to two species of lepidopterous larvae 

    E-Print Network [OSTI]

    Martin, Hugo Danilo

    1957-01-01T23:59:59.000Z

    COMPARISON GF STOMACH AND CONTACT TOXICITIES OF TOXAPHENE AND GKH ION By HUGO D. MARTIN A Thesis Submitted to the Graduate School of the Agricultural and Mechanical College of T!sxas in partial fulfillment of the requirements for the degree... of MASTER GF SCIENCE May 1957 Ms/or Sub)cot: ENTOMOLOGY COMPARISON GF STOMACH AND CONTACT TOXICITIES OF TO~ AND GUTHIGN TNO SPECIES OF LEPROUS LARVAE HUGO D. MARTIN Approved as to style and content by: irjasn of Committee ead o the Department lhe...

  13. The toxic levels of Microcide, a chlorine compound, for selected fishes 

    E-Print Network [OSTI]

    Champ, Michael Augustus

    1969-01-01T23:59:59.000Z

    THE TOXIC LEVELS OF M)CROCIDE, A CHLORINE COMPOUND, FOR SELECTED FISHES A Thesis by Michael A. Champ Submitted to the Graduate College of Texas A=M University in partial fultillment of the requirement for the degree of MASTER OF SCIENCE May... !9S9 Majot Subject; Biology THE TOXIC LEVELS OF MICROCIDE, A CHLORIHE COMPOUND, FOR SELECTED FISHES A Thesis by MICHAEL A. CHAMP Approved as to style and content by: Ciairman of mmittee (Member j (He~mb r May 1&6& n ~~. n E&r;~ri ABSTRACT...

  14. Potential hazards of compound 1080 to selected nontarget wildlife when used in the toxic collar 

    E-Print Network [OSTI]

    Eastland, Warren George

    1983-01-01T23:59:59.000Z

    POTENTIAL NA7ARDS OF COMPOUND 1080 TO SELECTED NONTARGET WI~ DLIFE WHEN USED IN TliE TOXIC COLLAR A Thesis by WARREN GEORGE EASTLAND Submitted to the Graduate College of Texas AfM University in partial fulfillment of the requirement... for the degree of MASTER OF SCIENCE August 1983 Major Subject: Wild'life and Fisheries Sciences POTENTIAL HAZARDS OF COMPOUND 1080 TO SELECTED NONTARGET WILDLIFE WHEN USED IN THE TOXIC COLLAR A Thesis by WARREN GEORGE EASTLAND Approved as to style...

  15. The Toxicity of the Ripe Fruit of Blackbrush or Tarbrush (Flourensia cernua) for Sheep and Goats. 

    E-Print Network [OSTI]

    Mathews, F. P. (Frank Patrick)

    1944-01-01T23:59:59.000Z

    to the plant. When sheep and goats have continuous access to the plant and are not subjected to-handling during the winter months,there is no evidence that this p&k'of the ~lant is grazed in sufficient amounts to cause toxic effects. The plant has not been... associated with similar losses in cattle. 1 The toxicity of the ripe fruit was demonstrated by experimental i feeding to sheep and goats. o In this wark a marked variation in the ~ueceptihility of different iddividuals was observed, as well as a nar...

  16. Environmental links to interannual variability in shellfish toxicity in Cobscook Bay and eastern Maine, a strongly tidally mixed coastal region

    E-Print Network [OSTI]

    Townsend, David W.

    Environmental links to interannual variability in shellfish toxicity in Cobscook Bay and eastern e i n f o Keywords: Harmful algal blooms Gulf of Maine Cobscook Bay Shellfish toxicity a b s t r a c of Cobscook Bay, where strong tidal mixing tends to reduce seasonal variability in oceanographic properties

  17. A DNA hybridization assay to identify toxic dinoflagellates in coastal waters: detection of Karenia brevis in the Rookery

    E-Print Network [OSTI]

    A DNA hybridization assay to identify toxic dinoflagellates in coastal waters: detection of Karenia Abstract A DNA hybridization assay was developed in microtiter plate format to detect the presence of toxic colorimetric results, used a single hybridization temperature, and conserved the amount of genomic DNA utilized

  18. Results of toxicity tests and chemical analyses conducted on sediments collected from the TNX Outfall Delta Operable Unit, July 1999

    SciTech Connect (OSTI)

    Specht, W.L.

    2000-02-11T23:59:59.000Z

    In order to provide unit specific toxicity data that will be used to address critical uncertainty in the ecological risk assessment (ERA) for the TNX Outfall Delta Operable Unit (TNXOD OU), sediments were collected from eight locations in the Inner Swamp portion of the operable unit and two unit specific background locations. These samples were analyzed for total mercury, total uranium, and sediment toxicity.

  19. Cell-based measurements to assess physiological status of Pseudo-nitzschia multiseries, a1 toxic diatom2

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    .resmic.2011.06.005 #12;2 Abstract11 Diatoms of the genus Pseudo-nitzschia are potentially toxic microalgae at the beginning of the22 exponential phase, when lipid storage was high, which provided a metabolic energy source toxic.42 Tools to assess the physiological status of microalgae are still fairly scarce. Photosynthetic

  20. Toxicity cutoff of aromatic hydrocarbons for luminescence inhibition of Vibrio fischeri

    E-Print Network [OSTI]

    McFall-Ngai, Margaret

    Toxicity cutoff of aromatic hydrocarbons for luminescence inhibition of Vibrio fischeri So Polycyclic aromatic hydrocarbons a b s t r a c t Effects of individual petroleum hydrocarbons hydrocarbons, including benzene and its derivatives and polycyclic aromatic hydrocarbons (PAHs), were chosen

  1. Evaluation of air toxic emissions from advanced and conventional coal-fired power plants

    SciTech Connect (OSTI)

    Chu, P.; Epstein, M. [Electric Power Research Institute, Palo Alto, CA (United States); Gould, L. [Department of Energy, Pittsburgh, PA (United States); Botros, P. [Department of Energy, Morgantown, WV (United States)

    1995-12-31T23:59:59.000Z

    This paper evaluates the air toxics measurements at three advanced power systems and a base case conventional fossil fuel power plant. The four plants tested include a pressurized fluidized bed combustor, integrated gasification combined cycle, circulating fluidized bed combustor, and a conventional coal-fired plant.

  2. Bivalve embryo bioassay to assess the potential toxicity of dredged material before dumping

    SciTech Connect (OSTI)

    Quiniou, F. [IFREMER Brest, Plouzane (France)

    1995-12-31T23:59:59.000Z

    Dredged harbor sediments frequently contain a wide spectrum of contaminants in addition to a significant percentage of organic matter. Also, dredging and dumping activities into sea water, of these highly contaminated soil may induce a harmful effect on the environment. In France, in accordance with Oslo convention guidelines, a working group on dredging activities and environment (GEODE) created since 1991 decided to set up a pilot research program to assess the intrinsic toxicity of four harbor sludges. Intrinsic toxicity of harbor muds were tested by solid phase (whole sediment) and aqueous extract bioassays (sea water elutriates) using the sublethal toxicity test bivalve embryo bioassay (Crassostrea gigas). Elutriates enable them to detect the toxicity of contaminants which may be released in the soluble form into the water column during dredging operations. While, whole sediment integrate the synergistic effects of all the contaminants (hydrophilic and hydrophobic) including pore water. Bioassays results, correlated to chemical analysis, are compared to contaminant levels determined by French working group GEODE and Canadian sediment quality criteria.

  3. Toxicity of density separation media to Escherichia coli and Mycobacterium strain PC01

    E-Print Network [OSTI]

    Rockne, Karl J.

    Toxicity of density separation media to Escherichia coli and Mycobacterium strain PC01 studied how various density separation media affected the viability of Escherichia coli to quantify and the Environment, Rutgers, The State University of New Jersey, New Brunswick, NJ 08854, USA c Institute of Marine

  4. Evaluation of the atmospheric deposition of toxic contaminants to Puget Sound, appendices

    SciTech Connect (OSTI)

    Not Available

    1991-08-01T23:59:59.000Z

    The document contains the appendices for the report 'Evaluation of the Atmospheric Deposition of Toxic Contaminants to Puget Sound', (PB93-122208). Contents include Literature Survey; Meteorological Data; Laboratory Results - Six-Month Aerosol and Deposition Study; Emission Inventory; Laboratory Results--18-Day Receptor Modeling Field Study; Diffusion/Transport Modeling; Integration of Results; Supporting Documents.

  5. Toxicity of nickel to the earthworm and the applicability of the neutral red retention assay

    E-Print Network [OSTI]

    Hopkin, Steve

    Toxicity of nickel to the earthworm and the applicability of the neutral red retention assay JANECK of nickel on survival, growth, and reproduction of Eisenia veneta were investigated following 4 weeks of exposure to a nickel-chloride spiked loamy sand soil. The ability of a simple earthworm biomarker

  6. Toxicity of Nickel to a Soil-Dwelling Springtail, Folsomia metaria (Collembola: Isotomidae)

    E-Print Network [OSTI]

    Hopkin, Steve

    Toxicity of Nickel to a Soil-Dwelling Springtail, Folsomia ¢metaria (Collembola: Isotomidae) Janeck. to nickel via soil caused signi®cant mortality and reduced growth and reproductive output. Nickel may and important organisms in the soil ecosystem, the eect of nickel has not previously been studied

  7. Influences of water chemistry on the acute toxicity of lead to Pimephales promelas and Ceriodaphnia dubia

    E-Print Network [OSTI]

    Grosell, Martin

    Influences of water chemistry on the acute toxicity of lead to Pimephales promelas and Ceriodaphnia in gasoline and from Pb-based paints. Although such applications were phased out beginning in the 1970s to natural variability in receiving water chemistry that can differentially impact its chemical speciation

  8. Br J Nutr . Author manuscript Calcium carbonate suppresses haem toxicity markers without calcium

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Br J Nutr . Author manuscript Page /1 9 Calcium carbonate suppresses haem toxicity markers without-term studies in rats identified calcium carbonate as the most effective calcium salt to bind haem in vitro demonstrated that a diet containing 100 mol/g calcium carbonate did not promote aberrant crypt foci

  9. Examining the effect of sterol carrier protein-2 on phytanic acid toxicity 

    E-Print Network [OSTI]

    Chen, Cynthia

    2013-02-22T23:59:59.000Z

    acid. Phytanic acid accumulates to toxic levels in patients with defective or deficient numbers of peroxisomes, but little is known about how phytanic acid is taken up into the cell and incorporated into the peroxisome. Sterol carrier protein-2 (SCP-2...

  10. ASSESSMENT OF THE MODELS FOR THE ESTIMATION OF THE CO2 RELEASES TOXIC EFFECTS

    E-Print Network [OSTI]

    Boyer, Edmond

    the global warming due to high concentration of CO2 in the atmosphere. However, in case of massive accidental to specific properties regarding its triple point. Then, this CO2 flakes creation may be followed1 ASSESSMENT OF THE MODELS FOR THE ESTIMATION OF THE CO2 RELEASES TOXIC EFFECTS Frédéric Antoine

  11. Biomass and toxicity responses of poison ivy (Toxicodendron radicans) to elevated

    E-Print Network [OSTI]

    Mohan, Jacqueline E.

    Biomass and toxicity responses of poison ivy (Toxicodendron radicans) to elevated atmospheric CO2, and population biomass of poison ivy. The CO2 growth stimulation exceeds that of most other woody species in Central America, parts of Asia, Bermuda, and the Bahama Islands (5). It has been introduced in Europe (6

  12. EFFECTS OF BENZENE (A TOXIC COMPONENT OF PETROLEUM) ON SPAWNING PACIFIC HERRING, CLUPEA HARENGUS PALLASI

    E-Print Network [OSTI]

    EFFECTS OF BENZENE (A TOXIC COMPONENT OF PETROLEUM) ON SPAWNING PACIFIC HERRING, CLUPEA HARENGUS and larvae through yolk absorption, 43%. Exposure to benzene also induced premature spawning and resulted-labeled benzene and/or metabolites in ovarian eggs (14 times initial concentration in water in 24-48 h; 1.4 ILlig

  13. Hair Cell Differentiation in Chick Cochlear Epithelium after Aminoglycoside Toxicity: In Vivo and In Vitro Observations

    E-Print Network [OSTI]

    Rubel, Edwin

    Hair Cell Differentiation in Chick Cochlear Epithelium after Aminoglycoside Toxicity: In Vivo ear epithelia of mature birds regenerate hair cells after ototoxic or acoustic insult. The lack of progenitor cells has hampered the iden- tification of cellular and molecular interactions that regulate hair

  14. Age and Comorbid Illness Are Associated With Late Rectal Toxicity Following Dose-Escalated Radiation Therapy for Prostate Cancer

    SciTech Connect (OSTI)

    Hamstra, Daniel A. [Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, Michigan (United States)] [Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, Michigan (United States); Stenmark, Matt H.; Ritter, Tim [Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, Michigan (United States) [Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, Michigan (United States); Department of Radiation Oncology, Veterans Affairs Medical Center, Ann Arbor, Michigan (United States); Litzenberg, Dale; Jackson, William; Johnson, Skyler; Albrecht-Unger, Liesel; Donaghy, Alex; Phelps, Laura; Blas, Kevin; Halverson, Schuyler; Marsh, Robin; Olson, Karin [Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, Michigan (United States)] [Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, Michigan (United States); Feng, Felix Y., E-mail: ffeng@med.umich.edu [Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, Michigan (United States)

    2013-04-01T23:59:59.000Z

    Purpose: To assess the impacts of patient age and comorbid illness on rectal toxicity following external beam radiation therapy (EBRT) for prostate cancer and to assess the Qualitative Analysis of Normal Tissue Effects in the Clinic (QUANTEC) normal tissue complication probability (NTCP) model in this context. Methods and Materials: Rectal toxicity was analyzed in 718 men previously treated for prostate cancer with EBRT (?75 Gy). Comorbid illness was scored using the Charlson Comorbidity Index (CCMI), and the NTCP was evaluated with the QUANTEC model. The influence of clinical and treatment-related parameters on rectal toxicity was assessed by Kaplan-Meier and Cox proportional hazards models. Results: The cumulative incidence of rectal toxicity grade ?2 was 9.5% and 11.6% at 3 and 5 years and 3.3% and 3.9% at 3 and 5 years for grade ?3 toxicity, respectively. Each year of age predicted an increasing relative risk of grade ?2 (P<.03; hazard ratio [HR], 1.04 [95% confidence interval (CI), 1.01-1.06]) and ?3 rectal toxicity (P<.0001; HR, 1.14 [95% CI,1.07-1.22]). Increasing CCMI predicted rectal toxicity where a history of either myocardial infarction (MI) (P<.0001; HR, 5.1 [95% CI, 1.9-13.7]) or congestive heart failure (CHF) (P<.0006; HR, 5.4 [95% CI, 0.6-47.5]) predicted grade ?3 rectal toxicity, with lesser correlation with grade ?2 toxicity (P<.02 for MI, and P<.09 for CHF). An age comorbidity model to predict rectal toxicity was developed and confirmed in a validation cohort. The use of anticoagulants increased toxicity independent of age and comorbidity. NTCP was prognostic for grade ?3 (P=.015) but not grade ?2 (P=.49) toxicity. On multivariate analysis, age, MI, CHF, and an NTCP >20% all correlated with late rectal toxicity. Conclusions: Patient age and a history of MI or CHF significantly impact rectal toxicity following EBRT for the treatment of prostate cancer, even after controlling for NTCP.

  15. Prediction of Chest Wall Toxicity From Lung Stereotactic Body Radiotherapy (SBRT)

    SciTech Connect (OSTI)

    Stephans, Kevin L., E-mail: stephak@ccf.org [Department of Radiation Oncology, Taussig Cancer Center, Cleveland Clinic, Cleveland, OH (United States); Djemil, Toufik; Tendulkar, Rahul D. [Department of Radiation Oncology, Taussig Cancer Center, Cleveland Clinic, Cleveland, OH (United States); Robinson, Cliff G. [Department of Radiation Oncology, Siteman Cancer Center, Washington University, St Louis, MO (United States); Reddy, Chandana A.; Videtic, Gregory M.M. [Department of Radiation Oncology, Taussig Cancer Center, Cleveland Clinic, Cleveland, OH (United States)

    2012-02-01T23:59:59.000Z

    Purpose: To determine patient, tumor, and treatment factors related to the development of late chest wall toxicity after lung stereotactic body radiotherapy (SBRT). Methods and Materials: We reviewed a registry of 134 patients treated with lung SBRT to 60 Gy in 3 fractions who had greater than 1 year of clinical follow-up and no history of multiple treatments to the same lobe (n = 48). Patients were treated as per Radiation Therapy Oncology Group Protocol 0236 without specific chest wall avoidance criteria. The chest wall was retrospectively contoured. Thirty-two lesions measured less than 3 cm, and sixteen measured 3 to 5 cm. The median planning target volume was 29 cm{sup 3}. Results: With a median follow-up of 18.8 months, 10 patients had late symptomatic chest wall toxicity (4 Grade 1 and 6 Grade 2) at a median of 8.8 months after SBRT. No patient characteristics (age, diabetes, hypertension, peripheral vascular disease, or body mass index) were predictive for toxicity, whereas there was a trend for continued smoking (p = 0.066; odds ratio [OR], 4.4). Greatest single tumor dimension (p = 0.047; OR, 2.63) and planning target volume (p = 0.040; OR, 1.04) were correlated with toxicity, whereas distance from tumor edge to chest wall and gross tumor volume did not reach statistical significance. Volumes of chest wall receiving 30 Gy (V30) through 70 Gy (V70) were all highly significant, although this correlation weakened for V65 and V70 and maximum chest wall point dose only trended to significance (p = 0.06). On multivariate analysis, tumor volume was no longer correlated with toxicity and only V30 through V60 remained statistically significant. Conclusions: Tumor size and chest wall dosimetry are correlated to late chest wall toxicity. Only chest wall V30 through V60 remained significant on multivariate analysis. Restricting V30 to 30 cm{sup 3} or less and V60 to 3 cm{sup 3} or less should result in a 10% to 15% risk of late chest wall toxicity or lower.

  16. Peculiarities of Ferro-Antiferroelectric Phase Transitions 9. Alternative for dipole-glass description of properties of substances with coexisting ferroelectric and antiferroelectric phases

    E-Print Network [OSTI]

    V. M. Ishchuk; V. L. Sobolev

    2010-07-01T23:59:59.000Z

    It is demonstrated that the substances with small difference in the free energies of the ferroelectric and antiferroelectric phases possess a set of properties characteristic for the so-called "dipole glasses". Possible phase diagrams of the substances that can be misguidedly attributed to glasses are discussed. Main attention has been paid to the process of long-time relaxation of physical characteristics of these compounds after their state of thermodynamic equilibrium was disturbed by external influences. The long-time relaxation along with the pronounced frequency dependence of parameters (for example, dependence of dielectric or magnetic characteristics on the frequency of measuring field) is considered as main features due to which these systems are classified as dipole glasses. Our main purpose is to call attention to the fact that one has to be cautious during the interpretation of experimental results in substances with inhomogeneous states of coexisting domains of ferroelectric and antiferroelectric phases.

  17. Application of gas chromatography with open tubular columns and chemiluminescent detection to the determination of sulfur-containing substances in oil pollutions of sea water

    SciTech Connect (OSTI)

    Savchuk, S.A.; Rudenko, B.A. [Vernadsky Inst. of Geochemical and Analytical Chemistry, Moscow (Russian Federation); Brodskii, E.S. [Severtzov Inst. of Evolution Morphology and Ecology of Animals, Moscow (Russian Federation)

    1995-11-01T23:59:59.000Z

    Sulfur in the free state and in the form of sulfur-containing organic substances, such as thiols, alkylsulfides, thiacycloalkanes, and thiophenes, are permanently present in oils and in the organic matter of bottom sediments. There are three classes of crude oils that are categorized by the sulfur concentration. Low-sulfur oils contain up to 0.5% of sulfur, sulfurous oils contain from 0.51 to 2%, and high-sulfur oils contain more than 2% of sulfur. The substances of thiophene series are considered to be the most stable sulfur compounds in oils. They are formed at the diagenesis stage via the aromatization of thiacycloalkanes during the thermal maturing of petroleum. Therefore, the determination of the composition of sulfur-containing aromatic substances is very important for studying oil-formation processes.

  18. Pulmonary toxicity after exposure to military-relevant heavy metal tungsten alloy particles

    SciTech Connect (OSTI)

    Roedel, Erik Q., E-mail: Erik.Roedel@amedd.army.mil [Department of General Surgery, Tripler Army Medical Center, Honolulu, HI 96859 (United States); Cafasso, Danielle E., E-mail: Danielle.Cafasso@amedd.army.mil [Department of General Surgery, Tripler Army Medical Center, Honolulu, HI 96859 (United States); Lee, Karen W.M., E-mail: Karen.W.Lee@amedd.army.mil [Department of Clinical Investigation, Tripler Army Medical Center, Honolulu, HI 96859 (United States); Pierce, Lisa M., E-mail: Lisa.Pierce@amedd.army.mil [Department of Clinical Investigation, Tripler Army Medical Center, Honolulu, HI 96859 (United States)

    2012-02-15T23:59:59.000Z

    Significant controversy over the environmental and public health impact of depleted uranium use in the Gulf War and the war in the Balkans has prompted the investigation and use of other materials including heavy metal tungsten alloys (HMTAs) as nontoxic alternatives. Interest in the health effects of HMTAs has peaked since the recent discovery that rats intramuscularly implanted with pellets containing 91.1% tungsten/6% nickel/2.9% cobalt rapidly developed aggressive metastatic tumors at the implantation site. Very little is known, however, regarding the cellular and molecular mechanisms associated with the effects of inhalation exposure to HMTAs despite the recognized risk of this route of exposure to military personnel. In the current study military-relevant metal powder mixtures consisting of 92% tungsten/5% nickel/3% cobalt (WNiCo) and 92% tungsten/5% nickel/3% iron (WNiFe), pure metals, or vehicle (saline) were instilled intratracheally in rats. Pulmonary toxicity was assessed by cytologic analysis, lactate dehydrogenase activity, albumin content, and inflammatory cytokine levels in bronchoalveolar lavage fluid 24 h after instillation. The expression of 84 stress and toxicity-related genes was profiled in lung tissue and bronchoalveolar lavage cells using real-time quantitative PCR arrays, and in vitro assays were performed to measure the oxidative burst response and phagocytosis by lung macrophages. Results from this study determined that exposure to WNiCo and WNiFe induces pulmonary inflammation and altered expression of genes associated with oxidative and metabolic stress and toxicity. Inhalation exposure to both HMTAs likely causes lung injury by inducing macrophage activation, neutrophilia, and the generation of toxic oxygen radicals. -- Highlights: ? Intratracheal instillation of W–Ni–Co and W–Ni–Fe induces lung inflammation in rats. ? W–Ni–Co and W–Ni–Fe alter expression of oxidative stress and toxicity genes. ? W–Ni–Co induces a greater oxidative burst response than W–Ni–Fe in lung macrophages.

  19. Effect of irradiance spectra on the photoinduced toxicity of three polycyclic aromatic hydrocarbons

    SciTech Connect (OSTI)

    Diamond, S.A.; Mount, D.R.; Burkhard, L.P.; Ankley, G.T.; Makynen, E.A.; Leonard, E.N.

    2000-05-01T23:59:59.000Z

    Photoinduced toxicity of polycyclic aromatic hydrocarbons (PAHs) is dependent on the concentration of compounds present and the dose of light received. Of the light present, only those wavelengths absorbed by the compound have the potential to initiate the photochemical events underlying phototoxicity. This suggests that variation in light spectra present in natural waters, arising from variation in dissolved organic carbon composition, is an important determinant of phototoxicity risk in specific, PAH-contaminated waterbodies. To quantify the effect of environmentally realistic variation in light spectra on toxicity, brine shrimp (Artemia salina) assays were conducted under various light spectra and with three PAHs (pyrene, fluoranthene, and anthracene) of known phototoxicity potential. In these spectral assays, the total ultraviolet light present was equivalent; only the spectral characteristics varied. Based on the absorbance spectra of these PAHs, it was predicted that toxicity, quantified using immobilization as the endpoint, would vary significantly among light spectra in pyrene assays, but not in anthracene assays, and that variation in toxicity in fluoranthene assays would be intermediate. The results supported these assumptions. In the pyrene exposures, the glass filter time to 50% population immobilization (IT50) (39.5 min) was 117% longer than the KCr filter IT50 (18.2 min). In the fluoranthene exposures, the glass filter IT50 (49.5 min) was 27% longer than the KCr filter IT50 (39.1 min). In the anthracene exposures, the glass filter IT50 (62.2 min) was not statistically different from the KCr filter IT50 (63.8 min). Comparison of these results with the results of assays conducted under neutral-density filters (that change intensity but not spectral distribution) demonstrate that multiplying spectral intensity by wavelength-specific absorbance accurately predicts relative photoinduced toxicity among the experimental treatments. These results indicate that quantifying the spectral characteristics of PAH-contaminated aquatic environments may be an important component of risk assessment at these sites.

  20. How managing more efficiently substances in the design process of industrial products? An example from the aeronautics sector

    E-Print Network [OSTI]

    Lemagnen, Maud; Brissaud, Daniel

    2009-01-01T23:59:59.000Z

    Lowering environmental impacts of products, i.e. ecodesign, is considered today as a new and promising approach environment protection. This article focuses on ecodesign in the aeronautical sector through the analysis of the practices of a company that designs and produces engine equipments. Noise, gas emissions, fuel consumptions are the main environmental aspects which are targeted by aeronautics. From now on, chemical risk linked to the use of materials and production processes has to be traced, not only because of regulation pressure (e.g. REACh) but also because of customers requirements. So far, the aeronautical sector hasn't been focusing much on managing chemical risks at the design stage. However, new substances regulations notably require that chemical risk management should be by industries used as early as possible in their product development process. The aeronautics sector has therefore to elaborate new chemical risk management. The aim of this paper is to present a new method hat should be adap...

  1. Evaluation of few-view reconstruction parameters for illicit substance detection using fast-neutron transmission spectroscopy

    SciTech Connect (OSTI)

    Fink, C.L.; Humm, P.G.; Martin, M.M.; Micklich, B.J. [Argonne National Lab., IL (United States)] [Argonne National Lab., IL (United States)

    1996-06-01T23:59:59.000Z

    The authors have evaluated the performance of an illicit substance detection system that performs image reconstruction using the Maximum Likelihood algebraic reconstruction algorithm, a fe number of projections, and relatively coarse projection and pixel resolution. This evaluation was done using receiver operator curves and simulated data from the fast-neutron transmission spectroscopy system operated in a mode to detect explosives in luggage. The results show that increasing the number of projection angles is more important than increasing the projection resolution, the reconstructed pixel resolution, of the number of iterations in the Maximum Likelihood algorithm. A 100% detection efficiency with essentially no false positives is possible for a square block of RDX explosive, a projection resolution of 2 cm, a reconstructed pixel size of 2x2 cm, and five projection angles. For rectangular shaped explosives more angles are required to obtain the same system performance.

  2. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans Some Inorganic Substances, Chlorinated Hydrocarbons, Aromatic Amines, N-Nitroso Compounds,

    E-Print Network [OSTI]

    Barthelat, Francois

    Inorganic Substances, Chlorinated Hydrocarbons, Aromatic Amines, N-Nitroso Compounds, and Natural Products 1973; 181 pages ISBN 92 832 1202 9 (out of print) Volume 3 Certain Polycyclic Aromatic Hydrocarbons, and Acrolein 1979; 513 pages ISBN 92 832 1219 3 (out of print) Volume 20 Some Halogenated Hydrocarbons 1979

  3. Pharmaceutical waste may be a hazardous chemical waste, controlled substance or biomedical waste. Proper classification is necessary to be in compliance with the laws regulating each waste type.

    E-Print Network [OSTI]

    George, Steven C.

    Pharmaceutical waste may be a hazardous chemical waste, controlled substance or biomedical waste. Hazardous Chemical Pharmaceutical Waste: A number of common pharmaceuticals are regulated as hazardous or more of the EPA characteristics of a hazardous chemical waste are also regulated as a hazardous

  4. A New Look at Natural Humics on Uranium Stability and Mobility Humic substances naturally forming organic materials in soil and groundwater, have

    E-Print Network [OSTI]

    A New Look at Natural Humics on Uranium Stability and Mobility Humic substances ­ naturally forming are significant because humics could present a potential challenge to immobilizing and stabilizing reduced uranium uranium bioreduction and oxidation. Environ. Sci. Technol. (in press). #12;

  5. Evaluation of the atmospheric deposition of toxic contaminants to Puget Sound

    SciTech Connect (OSTI)

    Not Available

    1991-08-01T23:59:59.000Z

    A growing recognition of the potential for transfer of pollutants from air to water prompted the study of the contribution of airborne toxic contaminants to water quality problems in Puget Sound. The study objectives were: (1) to develop a better understanding of the relative contribution of atmospheric deposition to toxic contaminants in Commencement Bay and (2) to develop efficient and cost-effective tools which could be used for assessing the question in other Puget Sound reaches and embayments. Commencement Bay was selected to represent a 'worst case' test area in Puget Sound because it is heavily industrialized, having a complex mix of air pollution sources and high concentrations of chemicals in the bay sediments. The study design included sampling and analysis for metals, polycyclic aromatic hydrocarbons, PCBs, aliphatic hydrocarbons, and nutrients. Several mathematical models were created or modified for the study.

  6. Identifying Biomarkers and Mechanisms of Toxic Metal Stress with Global Proteomics

    SciTech Connect (OSTI)

    Miller, Susan M.

    2012-04-16T23:59:59.000Z

    Hg is a wide-spread contaminant in the environment and is toxic in all of its various forms. Data suggest that RHg+ and Hg2+ are toxic in two ways. At low levels, Hg species appear to disrupt membrane-bound respiration causing a burst of reactive oxygen species (ROS) that further damage the cell. At higher Hg concentrations, RHg+ and Hg2+ may form adducts with cysteine- and selenocysteine-containing proteins in all cellular compartments resulting in their inactivation. Although these mechansims for toxicity are generally accepted, the most sensitive targets associated with these mechanisms are not well understood. In this collaborative project involving three laboratories at three institutions, the overall goal was to develop of a mass spectrometry-based global proteomics methodology that could be used to identify Hg-adducted (and ideally, ROS-damaged) proteins in order to address these types of questions. The two objectives of this overall collaborative project were (1) to identify, quantify, and compare ROS- and Hg-damaged proteins in cells treated with various Hg species and concentrations to test this model for two mechanisms of Hg toxicity, and (2) to define the cellular roles of the ubiquitous bacterial mercury resistance (mer) locus with regards to how the proteins of this pathway interact to protect other cell proteins from Hg damage. The specific objectives and accomplishments of the Miller lab in this project included: (1) Development of algorithms for analysis of the Hg-proteomic mass spectrometry data to identify mercury adducted peptides and other trends in the data. (2) Investigation of the role of mer operon proteins in scavenging Hg(II) from other mer pathway proteins as a means of protecting cellular proteins from damage.

  7. The quantification of oxygen toxicity by the technique of cellulose acetate electrophoresis of rat serum proteins

    E-Print Network [OSTI]

    Barker, Marcia Wagner

    1979-01-01T23:59:59.000Z

    symptoms of atelectasis, pulmonary edema, congestion and consolidation of the lungs, alveoli filled with a granular fibrillar exudate, and a general pneumonic condition. Therefore, pulmonary pathology associated with oxygen toxicity has been termed... the epithelial cells of the lungs are in direct contact with the changes in partial pressures of oxygen. Exposure to oxygen at increased partial pressures has had some dramatic effects on the circulatory system, such as increased osmotic fragility (96, 105...

  8. Hanford Waste Vitrification Plant technical background document for toxics best available control technology demonstration

    SciTech Connect (OSTI)

    none,

    1992-10-01T23:59:59.000Z

    This document provides information on toxic air pollutant emissions to support the Notice of Construction for the proposed Hanford Waste Vitrification Plant (HWVP) to be built at the the Department of Energy Hanford Site near Richland, Washington. Because approval must be received prior to initiating construction of the facility, state and federal Clean Air Act Notices of construction are being prepared along with necessary support documentation.

  9. Solidification/stabilization of toxic metal wastes using coke and coal combustion by-products

    SciTech Connect (OSTI)

    Vempati, R.K.; Mollah, M.Y.A.; Chinthala, A.K.; Cocke, D.L. [Lamar Univ., Beaumont, TX (United States)] [Lamar Univ., Beaumont, TX (United States); Beeghly, J.H. [Dravo Lime, Pittsburgh, PA (United States)] [Dravo Lime, Pittsburgh, PA (United States)

    1995-12-31T23:59:59.000Z

    A study has been conducted to evaluate the potential of a special rubber waste, NISCO Cyclone Ash (NCA), which contains substantial calcium oxide and calcium sulfites/sulfates for solidification/stabilization (S/S) of toxic metal wastes. The mineralogical compositions of the NCA and a class ``C`` fly ash have been characterized by X-ray diffraction (XRD). Hydrated mixtures of these wastes have been examined by XRD and found to form ettringite. Low concentrations of As (15 {micro}g ml{sup {minus}1}), Ba (500 {micro}g ml{sup {minus}1}), Pb (15 {micro}g ml{sup {minus}1}), and Zn (1,000 {micro}g ml{sup {minus}1}) were added to these hydrated mixtures and found to be successfully immobilized and solidified, as determined by the Toxicity Characteristic Leaching Procedure (TCLP). In addition, the mineralogy, chemistry and leaching characteristics of these combined waste products and their interactions with toxic metals are discussed.

  10. Air toxics provisions of the Clean Air Act: Potential impacts on energy

    SciTech Connect (OSTI)

    Hootman, H.A.; Vernet, J.E.

    1991-11-01T23:59:59.000Z

    This report provides an overview of the provisions of the Clean Air Act and its Amendments of 1990 that identify hazardous air pollutant (HAP) emissions and addresses their regulation by the US Environmental Protection Agency (EPA). It defines the major energy sector sources of these HAPs that would be affected by the regulations. Attention is focused on regulations that would cover coke oven emissions; chromium emission from industrial cooling towers and the electroplating process; HAP emissions from tank vessels, asbestos-related activities, organic solvent use, and ethylene oxide sterilization; and emissions of air toxics from municipal waste combustors. The possible implications of Title III regulations for the coal, natural gas, petroleum, uranium, and electric utility industries are examined. The report discusses five major databases of HAP emissions: (1) TRI (EPA`s Toxic Release Inventory); (2) PISCES (Power Plant Integrated Systems: Chemical Emissions Studies developed by the Electric Power Research Institute); (3) 1985 Emissions Inventory on volatile organic compounds (used for the National Acid Precipitation Assessment Program); (4) Particulate Matter Species Manual (EPA); and (5) Toxics Emission Inventory (National Aeronautics and Space Administration). It also offers information on emission control technologies for municipal waste combustors.

  11. Air toxics provisions of the Clean Air Act: Potential impacts on energy

    SciTech Connect (OSTI)

    Hootman, H.A.; Vernet, J.E.

    1991-11-01T23:59:59.000Z

    This report provides an overview of the provisions of the Clean Air Act and its Amendments of 1990 that identify hazardous air pollutant (HAP) emissions and addresses their regulation by the US Environmental Protection Agency (EPA). It defines the major energy sector sources of these HAPs that would be affected by the regulations. Attention is focused on regulations that would cover coke oven emissions; chromium emission from industrial cooling towers and the electroplating process; HAP emissions from tank vessels, asbestos-related activities, organic solvent use, and ethylene oxide sterilization; and emissions of air toxics from municipal waste combustors. The possible implications of Title III regulations for the coal, natural gas, petroleum, uranium, and electric utility industries are examined. The report discusses five major databases of HAP emissions: (1) TRI (EPA's Toxic Release Inventory); (2) PISCES (Power Plant Integrated Systems: Chemical Emissions Studies developed by the Electric Power Research Institute); (3) 1985 Emissions Inventory on volatile organic compounds (used for the National Acid Precipitation Assessment Program); (4) Particulate Matter Species Manual (EPA); and (5) Toxics Emission Inventory (National Aeronautics and Space Administration). It also offers information on emission control technologies for municipal waste combustors.

  12. Nano/bio treatment of polychlorinated biphenyls with evaluation of comparative toxicity

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Le, Thao Thanh; Francis, Arokiasamy J.; Nguyen, Hoang Khanh; Jeon, Jong -Rok; Chang, Yoon -Seok

    2015-04-01T23:59:59.000Z

    The persistence of polychlorinated biphenyl (PCB) Aroclor 1248 in soils and sediments is a major concern because of its toxicity and presence at high concentrations. In this study, we developed an integrated remediation system for PCBs using chemical catalysis and biodegradation. The dechlorination of Aroclor 1248 was achieved by treatment with bimetallic nanoparticles Pd/nFe under anoxic conditions. Among the 32 PCB congeners of Aroclor 1248 examined, our process dechlorinated 99%, 92%, 84%, and 28% of tri-, tetra-, penta-, and hexachlorinated biphenyls, respectively. The resulting biphenyl was biodegraded rapidly by Burkholderia xenovorans LB400. Benzoic acid was detected as an intermediate during the biodegradation process. The toxicity of the residual PCBs after nano-bio treatment was evaluated in terms of toxic equivalent values which decreased from 33.8 × 10-5 ?g g-1 to 9.5 × 10-5 ?g g-1. The residual PCBs also had low cytotoxicity toward Escherichia coli as demonstrated by lower reactive oxygen species levels, lower glutathione peroxidase activity, and a reduced number of dead bacteria.

  13. Simultaneous gas-chromatographic determination of four toxic gases generally present in combustion atmospheres. Final report

    SciTech Connect (OSTI)

    Endecott, B.R.; Sanders, D.C.; Chaturvedi, A.K.

    1994-09-01T23:59:59.000Z

    Measurement of combustion gases produced by burning aircraft cabin materials poses a continuing limitation for smoke toxicity research. Since toxic effects of gases depend on both their concentrations and duration of exposures, frequent atmosphere sampling is necessary to define the concentration-time curve. A gas chromatographic method was developed for the simultaneous analyses of carbon monoxide (CO), hydrogen sulfide (H2S), sulfur dioxide (SO2), and hydrogen cyanide (HCN). The method utilized an MTI M200 dual-column gas chromatograph (GC) equipped with 4-m molecular sieve-5A and 8-m PoraPlot-U capillary columns and two low-volume, high-sensitivity thermal conductivity detectors. Detectability (ppm)/retention times (seconds) for the gases were: CO (100/28); H2S (50/26); SO2 (125/76); HCN (60/108). The method was effective for determining these gases in mixtures and in the combustion atmospheres generated by burning wool (CO, HCN, and H2S) and modacrylic (CO and HCN) fabrics. Common atmospheric gaseous or combustion products (oxygen, carbon dioxide, nitrogen, water vapor, and other volatiles) did not interfere with the analyses. However, filtration of the combustion atmospheres was necessary to prevent restriction of the GC sampling inlet by smoke particulates. The speed, sensitivity, and selectivity of this method make it suitable for smoke toxicity research and for evaluating performance of passenger protective breathing equipment.

  14. Nano/bio treatment of polychlorinated biphenyls with evaluation of comparative toxicity

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Le, Thao Thanh; Francis, Arokiasamy J.; Nguyen, Hoang Khanh; Jeon, Jong -Rok; Chang, Yoon -Seok

    2015-04-01T23:59:59.000Z

    The persistence of polychlorinated biphenyl (PCB) Aroclor 1248 in soils and sediments is a major concern because of its toxicity and presence at high concentrations. In this study, we developed an integrated remediation system for PCBs using chemical catalysis and biodegradation. The dechlorination of Aroclor 1248 was achieved by treatment with bimetallic nanoparticles Pd/nFe under anoxic conditions. Among the 32 PCB congeners of Aroclor 1248 examined, our process dechlorinated 99%, 92%, 84%, and 28% of tri-, tetra-, penta-, and hexachlorinated biphenyls, respectively. The resulting biphenyl was biodegraded rapidly by Burkholderia xenovorans LB400. Benzoic acid was detected as an intermediate duringmore »the biodegradation process. The toxicity of the residual PCBs after nano-bio treatment was evaluated in terms of toxic equivalent values which decreased from 33.8 × 10-5 ?g g-1 to 9.5 × 10-5 ?g g-1. The residual PCBs also had low cytotoxicity toward Escherichia coli as demonstrated by lower reactive oxygen species levels, lower glutathione peroxidase activity, and a reduced number of dead bacteria.« less

  15. High Throughput, Low Toxic Processing of Very Thin, High Efficiency CIGSS Solar Cells: Final Report, December 2008

    SciTech Connect (OSTI)

    Dhere, N. G.

    2009-04-01T23:59:59.000Z

    The work carried out during this project presents the use of diethylselenium or other organometallic precursors as low-toxicity alternative selenium sources for preparing a high-quality absorber.

  16. Toxic waste sites may cause health problems for millions1 By Erin Wayman for www.sciencenews.org2

    E-Print Network [OSTI]

    South Bohemia, University of

    , identified the toxic waste sites, such as lead15 battery recycling centers and former tanneries. For each percent of the lost healthy years. The team estimates that22 the three countries could house an additional

  17. The androgen receptor independent mechanism of toxicity of the novel anti-tumor agent 11[beta]-dichloro

    E-Print Network [OSTI]

    Fedele?, Bogdan I

    2009-01-01T23:59:59.000Z

    Inspired by the toxicity mechanism of cisplatin in testicular cancer, a series of bi-functional genotoxicants has been designed that supplement their DNA damaging properties with the ability to interact with tumor specific ...

  18. Responses of soil microbial and nematode communities to aluminum toxicity in vegetated oil-shale-waste lands

    E-Print Network [OSTI]

    Neher, Deborah A.

    Responses of soil microbial and nematode communities to aluminum toxicity in vegetated oil-shale and total Al concentrations showed a significant decrease after planting S. cumini plantation onto the shale

  19. Quality of Life and Toxicity From Passively Scattered and Spot-Scanning Proton Beam Therapy for Localized Prostate Cancer

    SciTech Connect (OSTI)

    Pugh, Thomas J. [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Munsell, Mark F. [Department of Biostatistics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Choi, Seungtaek; Nguyen, Quyhn Nhu; Mathai, Benson [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Zhu, X. Ron; Sahoo, Narayan; Gillin, Michael; Johnson, Jennifer L.; Amos, Richard A. [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Dong, Lei [Scripps Proton Therapy Center, San Diego, California (United States); Mahmood, Usama; Kuban, Deborah A.; Frank, Steven J.; Hoffman, Karen E.; McGuire, Sean E. [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Lee, Andrew K., E-mail: aklee@mdanderson.org [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States)

    2013-12-01T23:59:59.000Z

    Purpose: To report quality of life (QOL)/toxicity in men treated with proton beam therapy for localized prostate cancer and to compare outcomes between passively scattered proton therapy (PSPT) and spot-scanning proton therapy (SSPT). Methods and Materials: Men with localized prostate cancer enrolled on a prospective QOL protocol with a minimum of 2 years' follow-up were reviewed. Comparative groups were defined by technique (PSPT vs SSPT). Patients completed Expanded Prostate Cancer Index Composite questionnaires at baseline and every 3-6 months after proton beam therapy. Clinically meaningful differences in QOL were defined as ?0.5 × baseline standard deviation. The cumulative incidence of modified Radiation Therapy Oncology Group grade ?2 gastrointestinal (GI) or genitourinary (GU) toxicity and argon plasma coagulation were determined by the Kaplan-Meier method. Results: A total of 226 men received PSPT, and 65 received SSPT. Both PSPT and SSPT resulted in statistically significant changes in sexual, urinary, and bowel Expanded Prostate Cancer Index Composite summary scores. Only bowel summary, function, and bother resulted in clinically meaningful decrements beyond treatment completion. The decrement in bowel QOL persisted through 24-month follow-up. Cumulative grade ?2 GU and GI toxicity at 24 months were 13.4% and 9.6%, respectively. There was 1 grade 3 GI toxicity (PSPT group) and no other grade ?3 GI or GU toxicity. Argon plasma coagulation application was infrequent (PSPT 4.4% vs SSPT 1.5%; P=.21). No statistically significant differences were appreciated between PSPT and SSPT regarding toxicity or QOL. Conclusion: Both PSPT and SSPT confer low rates of grade ?2 GI or GU toxicity, with preservation of meaningful sexual and urinary QOL at 24 months. A modest, yet clinically meaningful, decrement in bowel QOL was seen throughout follow-up. No toxicity or QOL differences between PSPT and SSPT were identified. Long-term comparative results in a larger patient cohort are warranted.

  20. Nitzschia pungens Grunow f. multiseries Hasle: growth phases and toxicity of clonal cultures isolated from Galveston, Texas 

    E-Print Network [OSTI]

    Reap, Maureen Elizabeth

    1991-01-01T23:59:59.000Z

    NITZSCHIA PUNGE1VS GRUNOW F. MULTISERIES HASLE: GROWTH PHASES AND TOXICITY OF CLONAL CULTURES ISOLATED FROM GALVESTON, TEXAS A Thesis by MAUREEN ELIZABETH REAP Submitted to the Once of Graduate Studies of Texas AkM University in partial... fulfillment of the requirements for the degree of MASTER OF SCIENCE May 1991 Major Subject: Oceanography NITZSCHIA PUNGENS GRUNOW F. MUITISERIES HASLE: GROWTH PHASES AND TOXICITY OF CLONAL CULTURES ISOLATED FROM GALVESTON) TEXAS A Thesis by MAUREEN...

  1. Plant oils and mineral oils: effects as insecticide additives and direct toxicity to Heliothis virescens (F.) and Musca domestica L. 

    E-Print Network [OSTI]

    Ochou, Germain Ochou

    1985-01-01T23:59:59.000Z

    PLANT OILS AND MINERAL OILS: EFFECTS AS INSECTICIDE ADDITIVES AND DIRECT TOXICITY TO HELIOTHIS VIRESCENS (F. ) AND MUSCA DOMESTICA L. A Thesis by GERMAIN OCHOU OCHOU Submitted to the Graduate College of Texas A&M University in partial... fulfillment of the requirements for the degree of MASTER OF SCIENCE May 1985 Major Subject: Entomology PLANT OILS AND MINERAL OILS: EFFECTS AS INSECTICIDE ADDITIVES AND DIRECT TOXICITY TO HELIOTHIS VIRESCENS (F. ) AND MUSCA DOMESTICA L. A Thesis...

  2. Temperature/toxicity relationships of formulated permethrin (Pounce) and methamidophos (Monitor) with susceptible diamondback moth larvae (Lepidoptera: Plutellidae) 

    E-Print Network [OSTI]

    Magaro, Jude Joseph

    1994-01-01T23:59:59.000Z

    TEMPERATURE/TOXICITY RELATIONSHIPS OF FORMULATED PERMETHRIN (POUNCE) AND METHAMIDOPHOS (MONITOR) WITH SUSCEPTIBLE DIAMONDBACK MOTH LARVAE (LEPIDOPTERA: PLUTELLIDAE) A Thesis by JUDE JOSEPH MAGARO Submitted to the Office of Graduate Studies... of Texas A&M University in partial fullfillment of the requirements for the degree of MASTER OF SCIENCE May 1994 Major Subject: Entomology TEMPERATURE/TOXICITY RELATIONSHIPS OF FORMULATED PERMETHRIN (POUNCE) AND METHAMIDOPHOS (MONITOR...

  3. K Basin sludge polychlorinated biphenyl removal technology assessment

    SciTech Connect (OSTI)

    Ashworth, S.C.

    1998-08-25T23:59:59.000Z

    The two Hanford K Basins are water-filled concrete pools that contain over 2,100 metric tons of N Reactor fuel elements stored in aluminum or stainless steel canisters. During the time the fuel has been stored, approximately 50 m3 of heterogeneous solid material have accumulated in the basins. This material, referred to as sludge, is a mixture of fuel corrosion products, metallic bits of spent fuel and zirconium clad iron and metal corrosion products and silica from migrating sands. Some of the sludges also contain PCBs. The congener group of PCBs was identified as Aroclor 1254. The maximum concentration of sludge PCBS was found to be 140 ppm (as settled wet basis). However, the distribution of the PCBs is non-uniform throughout the sludge (i.e., there are regions of high and low concentrations and places where no PCBs are present). Higher concentrations could be present at various locations. Aroclors 1016/1242, 1221, 1248, 1254, and 1260 were identified and quantified in K West (KW) Canister sludge. In some of these samples, the concentration of 1260 was higher than 1254. The sludge requires pre-treatment to meet tank farm waste acceptance criteria, Among the numerous requirements, the sludge should be retreated so that it does not contain regulated levels of Toxic Substances Control Act (TSCA) compounds. Because of their stable chemistry and relative insolubility in water, PCBs are difficult to treat. They also resist degradation from heat and electrical charges. This stability has resulted in environmental persistence which has prompted the development of a variety of new cleanup processes including supercritical processes, advanced oxidation, dehalogenation and others. Hopefully, most of the new processes are discussed herein. Information on new processes are being received and will be evaluated in a future revision.

  4. Evaluation of exposure limits to toxic gases for nuclear reactor control room operators

    SciTech Connect (OSTI)

    Mahlum, D.D.; Sasser, L.B. (Pacific Northwest Lab., Richland, WA (United States))

    1991-07-01T23:59:59.000Z

    We have evaluated ammonia, chlorine, Halon (actually a generic name for several halogenated hydro-carbons), and sulfur dioxide for their possible effects during an acute two-minute exposure in order to derive recommendations for maximum exposure levels. To perform this evaluation, we conducted a search to find the most pertinent literature regarding toxicity in humans and in experimental animals. Much of the literature is at least a decade old, not an unexpected finding since acute exposures are less often performed now than they were a few years ago. In most cases, the studies did not specifically examine the effects of two-minute exposures; thus, extrapolations had to be made from studies of longer-exposure periods. Whenever possible, we gave the greatest weight to human data, with experimental animal data serving to strengthen the conclusion arrived at from consideration of the human data. Although certain individuals show hypersensitivity to materials like sulfur dioxide, we have not attempted to factor this information into the recommendations. After our evaluation of the data in the literature, we held a small workshop. Major participants in this workshop were three consultants, all of whom were Diplomates of the American Board of Toxicology, and staff from the Nuclear Regulatory Commission. Our preliminary recommendations for two-minute exposure limits and the rationale for them were discussed and consensus reached on final recommendations. These recommendations are: (1) ammonia-300 to 400-ppm; (2) chlorine-30 ppm; (3) Halon 1301-5%; Halon 1211-2%; and (4) sulfur dioxide-100 ppm. Control room operators should be able to tolerate two-minute exposures to these levels, don fresh-air masks, and continue to operate the reactor if the toxic material is eliminated, or safely shut down the reactor if the toxic gas remains. 96 refs., 9 tabs.

  5. Toxic Release Inventory (TRI), Iowa, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to-Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99- 499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  6. Toxic Release Inventory (TRI), Delaware, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to-Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99- 499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  7. Toxic Release Inventory (TRI), Colorado, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to-Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99- 499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  8. Toxic Release Inventory (TRI), Massachusetts, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to- Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  9. Toxic Release Inventory (TRI), Illinois, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to-Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99- 499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  10. Toxic Release Inventory (TRI), Florida, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to-Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99- 499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  11. Toxic Release Inventory (TRI), Wisconsin, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to- Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  12. Toxic Release Inventory (TRI), Kentucky, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to-Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off-site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  13. Toxic Release Inventory (TRI), Connecticut, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to-Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99- 499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility; the first nine digit alphanumeric number a facility holds under the National Pollutant Discharge Elimination Systems.

  14. Toxic Release Inventory (TRI), Ohio, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to- Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  15. Toxic Release Inventory (TRI), Utah, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to- Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  16. Toxic Release Inventory (TRI), Hawaii, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to-Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99- 499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  17. Toxic Release Inventory (TRI), Missouri, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to- Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  18. Toxic Release Inventory (TRI), Minnesota, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to- Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  19. Toxic Release Inventory (TRI), Michigan, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to- Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  20. Toxic Release Inventory (TRI), Georgia, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to-Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99- 499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  1. Toxic Release Inventory (TRI), Arkansas, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to-Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99- 499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  2. Toxic Release Inventory (TRI), Kansas, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to-Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off-site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  3. Toxic Release Inventory (TRI), Nevada, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to- Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  4. Toxic Release Inventory (TRI), Nebraska, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to- Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  5. Toxic Release Inventory (TRI), Maryland, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to- Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  6. Toxic Release Inventory (TRI), Oklahoma, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to- Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  7. Toxic Release Inventory (TRI), Arizona, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to-Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99- 499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  8. Toxic Release Inventory (TRI), Louisiana, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to- Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  9. Toxic Release Inventory (TRI), Montana, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to- Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  10. Toxic Release Inventory (TRI), Indiana, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to-Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99- 499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  11. Toxic Release Inventory (TRI), Alaska, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to- Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year.Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  12. Toxic Release Inventory (TRI), Pennsylvania, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to- Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility; the first nine digit alphanumeric number a facility holds under the National Pollutant Discharge Elimination Systems.

  13. Toxic Release Inventory (TRI), Oregon, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to- Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  14. Toxic Release Inventory (TRI), Vermont, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to- Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  15. Toxic Release Inventory (TRI), Mssissippi, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to- Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  16. Toxic Release Inventory (TRI), Tennessee, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to- Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  17. Toxic Release Inventory (TRI), California, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to-Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99- 499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  18. Toxic Release Inventory (TRI), Washington, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to- Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  19. Toxic Release Inventory (TRI), Wyoming, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to- Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  20. Toxic Release Inventory (TRI), Idaho, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to-Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99- 499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  1. Toxic Release Inventory (TRI), Alabama, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to- Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year.Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  2. Toxic Release Inventory (TRI), Texas, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to- Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  3. Toxic Release Inventory (TRI), Maine, 1991 and 1992 (in Dbase III plus) (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1992-01-01T23:59:59.000Z

    The Toxic Chemical Release Inventory (TRI) data gives annual estimated releases of toxic chemicals to the environment for the area indicated. Section 313 of the Emergency Planning and Community Right-to- Know Act (also known as Title III) of the Superfund Amendments and Reauthorization Act (SARA) of 1986 (Public Law 99-499) requires EPA to establish an inventory of toxic chemical emissions from certain facilities. Section 313 informs the public of the presence of chemicals in their communities and releases of these chemicals into the community. With this information, States and communities, working with industrial facilities required to comply with this law, will be better able to protect public health and the environment. The TRI data on diskette includes (1) the names, addresses, counties, and public contacts of facilities manufacturing, processing or using the reported chemicals; (2) the SIC code for the plants; (3) the chemical involved; and (4) the estimated quantity emitted into the air (point and non-point emissions), discharged into bodies of water, injected underground, released to land, or released to publicly owned treatment works. Beginning with the 1991 reports, facilities also are required to provide information about pollution prevention and source reduction activities. New data elements include quantities of the listed chemical recycled and used for energy recovery on-site; quanties transferred off- site for recycling and energy recovery. Source reduction activities, and methods used to indentify those activities. All releases are in pounds per year. Also provided is the FIPS code corresponding to the facility state and county; the unique ID number assigned by Dun and Bradstreet to the parent company of the reporting facility as well as the name of the corporation or other business entity that owns or controls the reporting facility.

  4. Acute environmental toxicity and persistence of methyl salicylate: A chemical agent simulant. Final report

    SciTech Connect (OSTI)

    Cataldo, D.A.; Ligotke, M.W.; Harvey, S.D.; Fellows, R.J.; Li, S.W.

    1994-06-01T23:59:59.000Z

    The interactions of methyl salicylate with plant foliage and soils were assessed using aerosol/vapor exposure methods. Measurements of deposition velocity and residence times for soils and foliar surfaces are reported. Severe plant contact toxicity was observed at foliar mass-loading levels above 4 {mu}g/cm{sup 2} leaf; however, recovery was noted after four to fourteen days. Methyl salicylate has a short-term effect on soil dehydrogenase activity, but not phosphatase activity. Results of the earthworm bioassay indicated only minimal effects on survival.

  5. Optimizing electric utility air toxics compliance with other titles of the Clean Air Act

    SciTech Connect (OSTI)

    Loeb, A.P.; South, D.W.

    1993-12-31T23:59:59.000Z

    This paper provides an overview of regulatory issues under Title III of the Clean Air Act Amendments that could affect electric utilities. Title III contains provisions relating to hazardous air pollutants (HAPs) and provides special treatment for electric utilities. Generally, this discussion documents that if utility toxic emissions are regulated, one of the chief difficulties confronting utilities will be the lack of coordination between Title III and other titles of the Act. The paper concludes that if the US Environmental Protection Agency (EPA) determines that regulation of utility HAPs is warranted under Title III, savings can be realized from flexible compliance treatment.

  6. Toxic species emissions from controlled combustion of selected automotive rubber components

    E-Print Network [OSTI]

    Shalkowski, Mark Henry

    1993-01-01T23:59:59.000Z

    to change significantly in the future. It is estimated that by the year 2010, about one half of the MSW in the United States will be incinerated in energy-recovery facilities (8). With this much of our MSW to be incinerated, the issue of toxic species... being introduced to the environment through incinerator emissions and ash must be addressed. Over the last 20 years, more than 100 waste-to-energy plants have been built in the United States. There are almost that many plants currently either...

  7. Toxic species emissions from controlled combustion of selected rubber and plastic consumer products

    E-Print Network [OSTI]

    Caraballo, Simon A.

    1992-01-01T23:59:59.000Z

    on cascade impactor analysis) were found during the particle size distribution analysis made. At the same time, toxic heavy metals, such as lead, chromium and antimony, were detected in the smoke and ashes of some of the materials. During municipal..., HCN, and SOz. . . 24 TABLE 5. Andersen Ambient Sampler Cut-off Points. . . 29 TABLE 6. Comparison of Coefficients of Variation. . . 33 TABLE 7. Smoke Mass Test Results For Material V-S1. . 34 TABLE 8. Smoke Mass Test Results For Material C-S2...

  8. Migration and Retardation of Chemical Toxic Components from Radioactive Waste - Hydrochemical Aspects

    SciTech Connect (OSTI)

    Jedinakova-Krizova, V.; Hanslik, E.

    2003-02-24T23:59:59.000Z

    A systematic analysis of nuclear power plant (NPP) operation and radioactive wastes disposal (near-surface disposal and geologic disposal) in underground repositories has provided the basis for a comparison between the radiotoxicity and chemotoxicity as part of an EIA (environmental impact assessment) procedure. This contribution summarizes the hydrochemical mechanisms of transport and retardation processes, chemistry and migration behavior of radionuclides and chemical toxics in natural sorbents, especially bentonites. The effect of solubility and dissolution reactions, diffusion and sorption/desorption, complexation and variations in the aqueous phase composition, pH-value and oxidation-reduction properties and other phenomena affecting distribution coefficients (Kd values) is discussed.

  9. Comparative toxicity of several sulphurs to two species of spider mites attacking cotton

    E-Print Network [OSTI]

    Arrese, Luis Humberto

    1957-01-01T23:59:59.000Z

    new insecticides, such as parathion and Systox. With the development of the chlorinated hydrocarbon insecticides for use on cotton, it was found that sulphur added as a diluent, was of value in improving the dusting qualities of these materials... for the degree of May I957 Me/or Sub/act: Entcwology CQI'ARATIVE TOXICITY OF SEVERAL SULPHURS TO TWO SPECIES OF SPIUER MITES ATTACKING A 'Ihesis By Approved as to style anS content by: izaan of Cossaittee May l957 ACKH(WISDGHNEHT The author wishes...

  10. Toxicity of ammonia to larvae of the freshwater shrimp, Macrobrachium rosenbergii

    E-Print Network [OSTI]

    Llobrera, Jose Alvarez

    1979-01-01T23:59:59.000Z

    , [Ammonia-N] = the measured concentration of total ammonia as nitrogen, pK' = the mixed acidity-constant of the reaction, pH = the measured pH of the solution. The pK ' value for 12 ppt salinity solutions can be a computed using the procedure outlined...TOXICITY OF AMMONIA TO LARVAE OF THE FRESHWATER SHRIMP, MACR OBRACHIUM R OSENBERGI I A Thesis by JOSE ALVAREZ LLOBRERA Submitted to the Graduate College of Texas ARM University in partial fulfillment of the requirement for the degree...

  11. Characterization of air toxics from a laboratory coal-fired combustor

    SciTech Connect (OSTI)

    NONE

    1995-04-03T23:59:59.000Z

    Emissions of hazardous air pollutants from coal combustion were studied in a laboratory-scale combustion facility, with emphasis on fine particles in three size ranges of less than 7.5 {mu}m diameter. Vapors were also measured. Substances under study included organic compounds, anions, elements, and radionuclides. Fly ash was generated by firing a bituminous coal in a combuster for 40 h at each of two coal feed rates. Flue gas was sampled under two conditions. Results for organic compounds, anions, and elements show a dependence on particle size consistent with published power plant data. Accumulation of material onto surface layers was inferred from differences in chemical composition between the plume simulating dilution sampler and hot flue samples. Extracts of organic particulate material were fractionated into different polarity fractions and analyzed by GC/MS. In Phase II, these laboratory results will be compared to emissions from a full-scale power plant burning the same coal.

  12. Hazardous Substance Release Reporting Under CERCLA, EPCR {section}304 and DOE Emergency Management System (EMS) and DOE Occurrence Reporting Requirements. Environmental Guidance

    SciTech Connect (OSTI)

    Traceski, T.T.

    1994-06-01T23:59:59.000Z

    Releases of various substances from DOE facilities may be subject to reporting requirements under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) and the Emergency Planning and Community Right-to-Know Act (EPCRA), as well as DOE`s internal ``Occurrence Reporting and Processing of Operations Information`` and the ``Emergency Management System`` (EMS). CERCLA and EPCPA are Federal laws that require immediate reporting of a release of a Hazardous Substance (HS) and an Extremely Hazardous Substance (EHS), respectively, in a Reportable Quantity (RQ) or more within a 24-hour period. This guidance uses a flowchart, supplemental information, and tables to provide an overview of the process to be followed, and more detailed explanations of the actions that must be performed, when chemical releases of HSs, EHSs, pollutants, or contaminants occur at DOE facilities. This guidance should be used in conjunction with, rather than in lieu of, applicable laws, regulations, and DOE Orders. Relevant laws, regulations, and DOE Orders are referenced throughout this guidance.

  13. Control of Toxic Chemicals in Puget Sound, Phase 3: Study of Atmospheric Deposition of Air Toxics to the Surface of Puget Sound

    SciTech Connect (OSTI)

    Brandenberger, Jill M.; Louchouarn, Patrick; Kuo, Li-Jung; Crecelius, Eric A.; Cullinan, Valerie I.; Gill, Gary A.; Garland, Charity R.; Williamson, J. B.; Dhammapala, R.

    2010-07-05T23:59:59.000Z

    The results of the Phase 1 Toxics Loading study suggested that runoff from the land surface and atmospheric deposition directly to marine waters have resulted in considerable loads of contaminants to Puget Sound (Hart Crowser et al. 2007). The limited data available for atmospheric deposition fluxes throughout Puget Sound was recognized as a significant data gap. Therefore, this study provided more recent or first reported atmospheric deposition fluxes of PAHs, PBDEs, and select trace elements for Puget Sound. Samples representing bulk atmospheric deposition were collected during 2008 and 2009 at seven stations around Puget Sound spanning from Padilla Bay south to Nisqually River including Hood Canal and the Straits of Juan de Fuca. Revised annual loading estimates for atmospheric deposition to the waters of Puget Sound were calculated for each of the toxics and demonstrated an overall decrease in the atmospheric loading estimates except for polybrominated diphenyl ethers (PBDEs) and total mercury (THg). The median atmospheric deposition flux of total PBDE (7.0 ng/m2/d) was higher than that of the Hart Crowser (2007) Phase 1 estimate (2.0 ng/m2/d). The THg was not significantly different from the original estimates. The median atmospheric deposition flux for pyrogenic PAHs (34.2 ng/m2/d; without TCB) shows a relatively narrow range across all stations (interquartile range: 21.2- 61.1 ng/m2/d) and shows no influence of season. The highest median fluxes for all parameters were measured at the industrial location in Tacoma and the lowest were recorded at the rural sites in Hood Canal and Sequim Bay. Finally, a semi-quantitative apportionment study permitted a first-order characterization of source inputs to the atmosphere of the Puget Sound. Both biomarker ratios and a principal component analysis confirmed regional data from the Puget Sound and Straits of Georgia region and pointed to the predominance of biomass and fossil fuel (mostly liquid petroleum products such as gasoline and/or diesel) combustion as source inputs of combustion by-products to the atmosphere of the region and subsequently to the waters of Puget Sound.

  14. Evaluation of the effects of coal fly ash amendments on the toxicity of a contaminated marine sediment

    SciTech Connect (OSTI)

    Burgess, R.M.; Perron, M.M.; Friedman, C.L.; Suuberg, E.M.; Pennell, K.G.; Cantwell, M.G.; Pelletier, M.C.; Ho, K.T.; Serbst, J.R.; Ryba, S.A. [US EPA, Narragansett, RI (USA). Office for Research and Development

    2009-01-15T23:59:59.000Z

    Approaches for cleaning up contaminated sediments range from dredging to in situ treatment. In this study, we discuss the effects of amending reference and contaminated sediments with coal fly ash to reduce the bioavailability and toxicity of a field sediment contaminated with polycyclic aromatic hydrocarbons (PAHs). Six fly ashes and a coconut charcoal were evaluated in 7-d whole sediment toxicity tests with a marine amphipod (Ampelisca abdita) and mysid (Americamysis bahia). Fly ashes with high carbon content and the coconut charcoal showed proficiency at reducing toxicity. Some of the fly ashes demonstrated toxicity in the reference treatments. It is suspected that some of this toxicity is related to the presence of ammonia associated with fly ashes as a result of postoxidation treatment to reduce nitrous oxide emissions. Relatively simple methods exist to remove ammonia from fly ash before use, and fly ashes with low ammonia content are available. Fly ashes were also shown to effectively reduce overlying water concentrations of several PAHs. No evidence was seen of the release of the metals cadmium, copper, nickel, or lead from the fly ashes. A preliminary 28-d polychaete bioaccumulation study with one of the high-carbon fly ashes and a reference sediment was also performed. Although preliminary, no evidence was seen of adverse effects to worm growth or lipid content or of accumulation of PAHs or mercury from exposure to the fly ash. These data show fly ashes with high carbon content could represent viable remedial materials for reducing the bioavailability of organic contaminants in sediments.

  15. Effect of temperature on the release of intentionally and non-intentionally added substances from polyethylene terephthalate (PET) bottles into water

    E-Print Network [OSTI]

    Short, Daniel

    polyethylene terephthalate (PET) bottles into water: Chemical analysis and potential toxicity Cristina Bach a January 2013 Keywords: PET-bottled water By-products Chemical mixtures Cyto-genotoxicity Endocrine on the release of PET-bottle con- stituents into water and to assess the potential health hazard using in vitro

  16. Toxicity of corexit 9527 and Nigerian crude oil in vivo and in vitro

    SciTech Connect (OSTI)

    George, S.; Nelson, G.; Brooks, L. [Environmental Protection Agency, Research Triangle Park, NC (United States)] [and others

    1997-10-01T23:59:59.000Z

    When oil is spilled into aquatic systems, chemical dispersants frequently are applied to enhance emulsification and biological availability. In this study, toxicity of Corexit 9527 (Cx), a widely used dispersant, was evaluated with oil both in vivo and in vitro. Initially, both Cx and oil were bioassayed in a micro-suspension modification of the Salmonella reversion bioassay. Next, rats were dosed 5 weeks with oil, Cx or Cx/oil. Body and tissue weights, urine mutagenicity, and effect on intestinal enzymes and microbiota were determined. Cx (1:1000 dilution) was toxic in the bioassay and oil was negative (TA98 & TA100 +/-S9). Similar results were observed for urinary metabolites. Body and tissue weights were unaffected, but a significant reduction in small intestinal azo reductase (AR) and/or {beta}-glucuronidase (BG) was observed in animals that received Cx, oil, or Cx/oil. Effects on cecal AR were observed in the 3 treatment groups. One week nitroreductase (NR) activity was elevated, and 3 and 5 week BG activities were significantly different from controls. This correspond to an elimination of enterobacteria and enterococci in oil-treated rats and enterobacteria fluctuations in Cx- and Cx/oil-treated animals. Even though treatment of rats with Cx has no direct effect on the production of mutagenic urine metabolites from oil-treated animals, significant changes are observed in intestinal microbiota and their enzymes responsible for promutagen and procarcinogen activation.

  17. In vivo monitoring of toxic metals: assessment of neutron activation and x-ray fluorescence techniques

    SciTech Connect (OSTI)

    Ellis, K.J.

    1986-01-01T23:59:59.000Z

    To date, cadmium, lead, aluminum, and mercury have been measured in vivo in humans. The possibilities of monitoring other toxic metals have also been demonstrated, but no human studies have been performed. Neutron activation analysis appears to be most suitable for Cd and Al measurements, while x-ray fluorescence is ideally suited for measurement of lead in superficial bone. Filtered neutron beams and polarized x-ray sources are being developed which will improve in vivo detection limits. Even so, several of the current facilities are already suitable for use in epidemiological studies of selected populations with suspected long-term low-level ''environmental'' exposures. Evaluation and diagnosis of patients presenting with general clinical symptoms attributable to possible toxic metal exposure may be assisted by in vivo examination. Continued in vivo monitoring of industrial workers, especially follow-up measurements, will provide the first direct assessment of changes in body burden and a direct measure of the biological life-times of these metals in humans. 50 refs., 4 figs., 2 tabs.

  18. SOLOX coke-oven gas desulfurization ppm levels -- No toxic waste

    SciTech Connect (OSTI)

    Platts, M. (Thyssen Still Otto Technical Services, Pittsburgh, PA (United States)); Tippmer, K. (Thyssen Still Otto Anlagentechnik GmbH, Bochum (Germany))

    1994-09-01T23:59:59.000Z

    For sulfur removal from coke-oven gas, the reduction/oxidation processes such as Stretford are the most effective, capable of removing the H[sub 2]S down to ppm levels. However, these processes have, in the past, suffered from ecological problems with secondary pollutant formation resulting from side reactions with HCN and O[sub 2]. The SOLOX gas desulfurization system is a development of the Stretford process in which the toxic effluent problems are eliminated by installing a salt decomposition process operating according to the liquid-phase hydrolysis principle. In this process, the gaseous hydrolysis products H[sub 2]S, NH[sub 3] and CO[sub 2] are returned to the untreated gas, and the regenerated solution is recycled to the absorption process. The blowdown from the absorption circuit is fed into a tube reactor where the hydrolysis process takes place. The toxic salts react with water, producing as reaction products the gases H[sub 2]S, NH[sub 3] and CO[sub 2], and the nontoxic salt Na[sub 2]SO[sub 4]. From the hydrolysis reactor the liquid stream flows into a fractionating crystallization plant. This plant produces a recycle stream of regenerated absorption solution and a second stream containing most of the Na[sub 2]SO[sub 4]. This second stream comprises the net plant waste and can be disposed of with the excess ammonia liquor or sprayed onto the coal.

  19. Toxic chemical release inventory reporting: Questions and answers (Qs&As)

    SciTech Connect (OSTI)

    Not Available

    1994-03-01T23:59:59.000Z

    On September 22, 1992, the Secretary of Energy directed the Department to participate in the Environmental Protection Agency`s (EPA) 33/50 Pollution Prevention Program and to initiate Toxic Chemical Release Inventory (TRI) reporting, pursuant to Section 313 of the Emergency Planning and Community Right-to-Know Act (EPCRA), at Department of Energy (DOE) sites. The Office of Environmental Guidance, RCRA/CERCLA Division (EH-231) issued interim guidance on March 4, 1993, entitled ``Toxic Chemical Release Inventory and 33/50 Pollution Prevention Program`` that provided instructions on implementing the Secretarial directive. As stated in the interim guidance, all DOE sites not currently reporting under EPCRA Section 313, which meet the criteria for DOE TRI reporting, will initiate reporting of all TRI chemical releases and transfers for the 1993 calendar year with the annual report due to EPA, States and a courtesy copy to EH-20 by July 1, 1994. All other DOE sites which currently report under EPCRA Section 313 will also follow the criteria for DOE TRI reporting.

  20. Aquatic toxicity information on vax vms backup (AQUIRE for vms) (1600 bpi). Data file

    SciTech Connect (OSTI)

    NONE

    1993-03-31T23:59:59.000Z

    The purpose of AQUIRE is to provide scientists and managers quick access to a comprehensive, systematic, computerized compilation of aquatic toxicity data. During 1992 and early 1993, nine data updates were made to the AQUIRE system. AQUIRE now contains 109,338 individual aquatic toxicity test results for 5,159 chemicals, 2,429 organisms, and over 160 endpoints reviewed from 7,517 publications. New features include a data selection option that permits searches that are restricted to data added or modified through any of the eight most recent updates, and a report generation (Full Record Detail) that displays the entire AQUIRE record for each test identified in a search. Selection of the Full Record Detail feature allows the user to peruse all AQUIRE fields for a given test, including the information stored in the remarks section, while the standard AQUIRE output format presents selected data fields in a concise table. The standard report remains an available option for rapid viewing of system output.

  1. Aquatic toxicity information on vax vms backup (AQUIRE for vms) (6250 bpi). Data file

    SciTech Connect (OSTI)

    NONE

    1994-03-01T23:59:59.000Z

    The purpose of AQUIRE is to provide scientists and managers quick access to a comprehensive, systematic, computerized compilation of aquatic toxicity data. During 1992 and early 1993, nine data updates were made to the AQUIRE system. AQUIRE now contains 109,338 individual aquatic toxicity test results for 5,159 chemicals, 2,429 organisms, and over 160 endpoints reviewed from 7,517 publications. New features include a data selection option that permits searches that are restricted to data added or modified through any of the eight most recent updates, and report generation (Full Record Detail) that displays the entire AQUIRE record for each test identified in a search. Selection of the Full Record Detail feature allows the user to peruse all AQUIRE fields for a given test, including the information stored in the remarks section, while the standard AQUIRE output format presents selected data fields in a concise table. The standard report remains an available option for rapid viewing of system output.

  2. Heavy-metal toxicity phenomena in laboratory-scale ANFLOW bioreactors

    SciTech Connect (OSTI)

    Rivera, A.L.

    1982-04-01T23:59:59.000Z

    An energy-conserving wastewater treatment system was developed based on an anaerobic, upflow (ANFLOW) bioreactor. Since many applications of the ANFLOW process could involve the treatment of wastewaters containing heavy metals, the potentially toxic effects of these metals on the biological processes occurring in ANFLOW columns (primarily acetogenesis and methanogenesis) were investigated. Both step and pulse inputs of zinc ranging from 100 to 1000 mg/L were added to synthetic wastewaters being treated in ANFLOW columns with 0.057-m/sup 3/ volumes. Column responses were used to develop descriptive models for toxicity phenomena in such systems. It was found that an inhibition function could be defined and used to modify a model based on plugflow with axial dispersion and first-order kinetics for soluble substrate removal. The inhibitory effects of zinc on soluble substrate removal were found to be predominantly associated with its sorption by biosolids. Sorption initially occurred in the lower regions of the column, but was gradually observed in higher regions as the sorption capacity of the lower regions was exhausted. Sorption phenomena could be described with the Freundlich equation. Sorption processes were accompanied by shifts of biological processes to regions higher in the columns. A regenerative process was observed when feeding of wastewaters without zinc was resumed. It was postulated that regeneration could be based on sloughing of layers of biofilms, or other biosolids involved in zinc sorption, followed by continued growth of lower layers of biofilms not involved in heavy-metal sorption.

  3. Small heat shock proteins protect against {alpha}-synuclein-induced toxicity and aggregation

    SciTech Connect (OSTI)

    Outeiro, Tiago Fleming [Alzheimer's Research Unit, MassGeneral Institute for Neurodegenerative Disease, MGH, Harvard Medical School, CNY 114, 16th Street, Charlestown, MA 02129 (United States); Klucken, Jochen [Alzheimer's Research Unit, MassGeneral Institute for Neurodegenerative Disease, MGH, Harvard Medical School, CNY 114, 16th Street, Charlestown, MA 02129 (United States); Strathearn, Katherine E. [Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47907-2091 (United States); Liu Fang [Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47907-2091 (United States); Nguyen, Paul [Alzheimer's Research Unit, MassGeneral Institute for Neurodegenerative Disease, MGH, Harvard Medical School, CNY 114, 16th Street, Charlestown, MA 02129 (United States); Rochet, Jean-Christophe [Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47907-2091 (United States); Hyman, Bradley T. [Alzheimer's Research Unit, MassGeneral Institute for Neurodegenerative Disease, MGH, Harvard Medical School, CNY 114, 16th Street, Charlestown, MA 02129 (United States); McLean, Pamela J. [Alzheimer's Research Unit, MassGeneral Institute for Neurodegenerative Disease, MGH, Harvard Medical School, CNY 114, 16th Street, Charlestown, MA 02129 (United States)]. E-mail: touteiro@partners.org

    2006-12-22T23:59:59.000Z

    Protein misfolding and inclusion formation are common events in neurodegenerative diseases, such as Parkinson's disease (PD), Alzheimer's disease (AD) or Huntington's disease (HD). {alpha}-Synuclein (aSyn) is the main protein component of inclusions called Lewy bodies (LB) which are pathognomic of PD, Dementia with Lewy bodies (DLB), and other diseases collectively known as LB diseases. Heat shock proteins (HSPs) are one class of the cellular quality control system that mediate protein folding, remodeling, and even disaggregation. Here, we investigated the role of the small heat shock proteins Hsp27 and {alpha}B-crystallin, in LB diseases. We demonstrate, via quantitative PCR, that Hsp27 messenger RNA levels are {approx}2-3-fold higher in DLB cases compared to control. We also show a corresponding increase in Hsp27 protein levels. Furthermore, we found that Hsp27 reduces aSyn-induced toxicity by {approx}80% in a culture model while {alpha}B-crystallin reduces toxicity by {approx}20%. In addition, intracellular inclusions were immunopositive for endogenous Hsp27, and overexpression of this protein reduced aSyn aggregation in a cell culture model.

  4. Biodegradation of nickel-citrate and modulation of nickel toxicity by iron

    SciTech Connect (OSTI)

    Francis, A.; Joshi-Tope, G.A.; Dodge, C.J. [Brookhaven National Lab., Upton, NY (United States)] [Brookhaven National Lab., Upton, NY (United States)

    1996-02-01T23:59:59.000Z

    Biodegradation of 1:1 nickel:citric acid by Pseudomonas fluorescens proceeded after a lag (nearly 17h) at the rate of 11{+-}1 {mu}mol h{sup -1}, with only partial mineralization of the complex. The incomplete degradation of the complex was not attributed to changes in its structure, but was due to the toxicity of the Ni released. Addition of 1:1 Ni:citric acid inhibited glucose metabolism by the bacterium. The toxicity of the released Ni was evident only when it attained a threshold concentration of > 0.3 mM in the culture medium. Speciation calculations showed that Ni released after metabolism of the complex was present as Ni{sup 2+} ion and nickel carbonate. Addition of iron as a ferric hydroxide or 1:1 Fe:citric acid to 1:1 Ni:citric acid resulted in the complete metabolism of the Ni-citrate complex, with concurrent removal of the released Ni from solution by coprecipitation with iron. 29 refs., 6 figs., 1 tab.

  5. Determination of the toxicity characteristic for metals in soil: A comparison of the toxicity characteristic leaching procedure and total metal determination

    SciTech Connect (OSTI)

    Bass, D.A.; Taylor, J.D.

    1994-12-01T23:59:59.000Z

    A comparison is made of the concentrations of metals extracted from soils using the Toxicity Characteristic Leaching Procedure (TCLP) and a total determination method. This information is of interest in two ways. First, it is hoped that a relationship might be established between the amount of each metal determined after extraction by the TCLP and the amount determined using a total determination method. And second, data are also presented which indicate the general extractability of various metals in soil samples using the TCLP. This study looks specifically at inorganic elements (Sb, As, Ba, Cd, Cu, Cr, Pb, Mg, Hg, Se, Ag, Sn, and Zn) in soils from a firing range. Results show that total determination methods for metals can not generally be used for heterogeneous samples, such as soil samples from a firing range. Some correlation between a total determination method and TCLP was observed when Ba and Cd were present in the samples at lower concentrations (less than 80 mg/kg for Ba and less than 25 mg/kg for Cd); however, additional data are necessary to verify this correlation.

  6. Guidance Document Carcinogenic Substances

    E-Print Network [OSTI]

    [a]pyrene Acrylonitrile Acrolein Natural products (including antitumor drugs) Ethyl acrylate Adriamycin Aflatoxins #12

  7. California | Connecticut | Illinois | Maine | Maryland | Massachusetts | Michigan | New Hampshire | New Jersey | New York | Oregon | Vermont | Washington STATES' PRINCIPLES ON REFORM OF THE

    E-Print Network [OSTI]

    | New Jersey | New York | Oregon | Vermont | Washington STATES' PRINCIPLES ON REFORM OF THE TOXIC chemical alternatives assessments. #12;States' Principles on Reform of the Toxic Substances Control Act

  8. Toxicity mitigation and solidification of municipal solid waste incinerator fly ash using alkaline activated coal ash

    SciTech Connect (OSTI)

    Ivan Diaz-Loya, E. [Alternative Cementitious Binders Laboratory (ACBL), Department of Civil Engineering, Louisiana Tech University, Ruston, LA 71272 (United States); Allouche, Erez N., E-mail: allouche@latech.edu [Alternative Cementitious Binders Laboratory (ACBL), Department of Civil Engineering, Louisiana Tech University, Ruston, LA 71272 (United States); Eklund, Sven; Joshi, Anupam R. [Department of Chemistry, Louisiana Tech University, Ruston, LA 71272 (United States); Kupwade-Patil, Kunal [Alternative Cementitious Binders Laboratory (ACBL), Department of Civil Engineering, Louisiana Tech University, Ruston, LA 71272 (United States)

    2012-08-15T23:59:59.000Z

    Highlights: Black-Right-Pointing-Pointer Incinerator fly ash (IFA) is added to an alkali activated coal fly ash (CFA) matrix. Black-Right-Pointing-Pointer Means of stabilizing the incinerator ash for use in construction applications. Black-Right-Pointing-Pointer Concrete made from IFA, CFA and IFA-CFA mixes was chemically characterized. Black-Right-Pointing-Pointer Environmentally friendly solution to IFA disposal by reducing its toxicity levels. - Abstract: Municipal solid waste (MSW) incineration is a common and effective practice to reduce the volume of solid waste in urban areas. However, the byproduct of this process is a fly ash (IFA), which contains large quantities of toxic contaminants. The purpose of this research study was to analyze the chemical, physical and mechanical behaviors resulting from the gradual introduction of IFA to an alkaline activated coal fly ash (CFA) matrix, as a mean of stabilizing the incinerator ash for use in industrial construction applications, where human exposure potential is limited. IFA and CFA were analyzed via X-ray fluorescence (XRF), X-ray diffraction (XRD) and Inductive coupled plasma (ICP) to obtain a full chemical analysis of the samples, its crystallographic characteristics and a detailed count of the eight heavy metals contemplated in US Title 40 of the Code of Federal Regulations (40 CFR). The particle size distribution of IFA and CFA was also recorded. EPA's Toxicity Characteristic Leaching Procedure (TCLP) was followed to monitor the leachability of the contaminants before and after the activation. Also images obtained via Scanning Electron Microscopy (SEM), before and after the activation, are presented. Concrete made from IFA, CFA and IFA-CFA mixes was subjected to a full mechanical characterization; tests include compressive strength, flexural strength, elastic modulus, Poisson's ratio and setting time. The leachable heavy metal contents (except for Se) were below the maximum allowable limits and in many cases even below the reporting limit. The leachable Chromium was reduced from 0.153 down to 0.0045 mg/L, Arsenic from 0.256 down to 0.132 mg/L, Selenium from 1.05 down to 0.29 mg/L, Silver from 0.011 down to .001 mg/L, Barium from 2.06 down to 0.314 mg/L and Mercury from 0.007 down to 0.001 mg/L. Although the leachable Cd exhibited an increase from 0.49 up to 0.805 mg/L and Pd from 0.002 up to 0.029 mg/L, these were well below the maximum limits of 1.00 and 5.00 mg/L, respectively.

  9. Mechanisms of olfactory toxicity of the herbicide 2,6-dichlorobenzonitrile: Essential roles of CYP2A5 and target-tissue metabolic activation

    SciTech Connect (OSTI)

    Xie Fang; Zhou Xin; Behr, Melissa; Fang Cheng; Horii, Yuichi; Gu Jun; Kannan, Kurunthachalam; Ding Xinxin, E-mail: xding@wadsworth.or

    2010-11-15T23:59:59.000Z

    The herbicide 2,6-dichlorobenzonitril (DCBN) is a potent and tissue-specific toxicant to the olfactory mucosa (OM). The toxicity of DCBN is mediated by cytochrome P450 (P450)-catalyzed bioactivation; however, it is not known whether target-tissue metabolic activation is essential for toxicity. CYP2A5, expressed abundantly in both liver and OM, was previously found to be one of the P450 enzymes active in DCBN bioactivation in vitro. The aims of this study were to determine the role of CYP2A5 in DCBN toxicity in vivo, by comparing the extents of DCBN toxicity between Cyp2a5-null and wild-type (WT) mice, and to determine whether hepatic microsomal P450 enzymes (including CYP2A5) are essential for the DCBN toxicity, by comparing the extents of DCBN toxicity between liver-Cpr-null (LCN) mice, which have little P450 activity in hepatocytes, and WT mice. We show that the loss of CYP2A5 expression did not alter systemic clearance of DCBN (at 25 mg/kg); but it did inhibit DCBN-induced non-protein thiol depletion and cytotoxicity in the OM. Thus, CYP2A5 plays an essential role in mediating DCBN toxicity in the OM. In contrast to the results seen in the Cyp2a5-null mice, the rates of systemic DCBN clearance were substantially reduced, while the extents of DCBN-induced nasal toxicity were increased, rather than decreased, in the LCN mice, compared to WT mice. Therefore, hepatic P450 enzymes, although essential for DCBN clearance, are not necessary for DCBN-induced OM toxicity. Our findings form the basis for a mechanism-based approach to assessing the potential risks of DCBN nasal toxicity in humans.

  10. Predictive Modelling of Toxicity Resulting from Radiotherapy Treatments of Head and Neck Cancer

    E-Print Network [OSTI]

    Dean, Jamie A; Harrington, Kevin J; Nutting, Christopher M; Gulliford, Sarah L

    2014-01-01T23:59:59.000Z

    In radiotherapy for head and neck cancer, the radiation dose delivered to the pharyngeal mucosa (mucosal lining of the throat) is thought to be a major contributing factor to dysphagia (swallowing dysfunction), the most commonly reported severe toxicity. There is a variation in the severity of dysphagia experienced by patients. Understanding the role of the dose distribution in dysphagia would allow improvements in the radiotherapy technique to be explored. The 3D dose distributions delivered to the pharyngeal mucosa of 249 patients treated as part of clinical trials were reconstructed. Pydicom was used to extract DICOM (digital imaging and communications in medicine) data (the standard file formats for medical imaging and radiotherapy data). NumPy and SciPy were used to manipulate the data to generate 3D maps of the dose distribution delivered to the pharyngeal mucosa and calculate metrics describing the dose distribution. Multivariate predictive modelling of severe dysphagia, including descriptions of the d...

  11. Clinch River - Environmental Restoration Program (CR-ERP) pilot study, ambient water toxicity

    SciTech Connect (OSTI)

    Simbeck, D.J.

    1997-06-01T23:59:59.000Z

    Clinch River - Environmental Restoration Program (CR-ERP) personnel and Tennessee Valley Authority (TVA) personnel conducted a pilot study during the week of April 22-29, 1993, prior to initiation of CR-ERP Phase II Sampling and Analysis activities as described in the Statement of Work (SOW) document. The organisms specified for testing were larval fathead minnows, Pimephales promelas, and the daphnid, Ceriodaphnia dubia. Surface water samples were collected by TVA Field Engineering personnel from Clinch River Mile 9.0 and Poplar Creek Kilometer 1.6 on April 21, 23, and 26. Samples were split and provided to the CR-ERP and TVA toxicology laboratories for testing. Exposure of test organisms to these samples resulted in no toxicity (survival, growth, or reproduction) to either species in testing conducted by TVA.

  12. BMY 30047: A novel topically active retinoid with low local and systemic toxicity

    SciTech Connect (OSTI)

    Nair, X.; Quigley, J.; Tramposch, K.M.; Carroll, F.I.; Lewin, A.H.; Kiss, I. (Bristol-Myers Squibb Co., Buffalo, NY (USA))

    1991-01-01T23:59:59.000Z

    In the treatment of various dermatological disorders, topically applied retinoids have potential therapeutic use with the advantage of improved localized activity and lower toxicity over systemically administered retinoids. However, most retinoids cause a significant degree of local irritation. In the present study, the ability to produce local activity with low local irritation potential was evaluated with a novel retinoic acid derivative. BMY 30047 (11-cis, 13-cis-12-hydroxymethylretinoic acid delta-lactone) is one of a series of retinoic acid derivatives in which the carboxyl function of the polar end was modified with the aim of achieving reduced local irritation and systemic toxicity while retaining the local therapeutic effect. BMY 30047 was evaluated and compared with all-trans retinoic acid for topical retinoid activity in several preclinical assay systems, including the utricle reduction assay in rhino mice, 12-o-tetradecanoylphorbol 13-acetate ester-stimulated ornithine decarboxylase induction in hairless mice and the UV light-induced photodamaged skin model in hairless mice. BMY 30047 was assessed for retinoid-type side effects by evaluating the skin irritation potential in rabbits after repeated topical application, and hypervitaminosis A-inducing potential in mice after i.p. injection. BMY 30047 demonstrated significant topical retinoid activity in several in vivo models with less skin irritation potential relative to the most used clinical concentrations of all-trans retinoic acid. BMY 30047 also showed very little systemic activity and did not produce any evidence of hypervitaminosis A syndrome at systemic doses 20 times greater than the no-effect dose of all-trans retinoic acid.

  13. Proton Beam Craniospinal Irradiation Reduces Acute Toxicity for Adults With Medulloblastoma

    SciTech Connect (OSTI)

    Brown, Aaron P. [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Barney, Christian L. [Baylor College of Medicine, Houston, Texas (United States)] [Baylor College of Medicine, Houston, Texas (United States); Grosshans, David R.; McAleer, Mary Frances [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Groot, John F. de; Puduvalli, Vinay K. [Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Tucker, Susan L. [Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Crawford, Cody N.; Khan, Meena [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Khatua, Soumen [Department of Pediatric Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [Department of Pediatric Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Gilbert, Mark R. [Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Brown, Paul D. [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Mahajan, Anita, E-mail: amahajan@mdanderson.org [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States)

    2013-06-01T23:59:59.000Z

    Purpose: Efficacy and acute toxicity of proton craniospinal irradiation (p-CSI) were compared with conventional photon CSI (x-CSI) for adults with medulloblastoma. Methods and Materials: Forty adult medulloblastoma patients treated with x-CSI (n=21) or p-CSI (n=19) at the University of Texas MD Anderson Cancer Center from 2003 to 2011 were retrospectively reviewed. Median CSI and total doses were 30.6 and 54 Gy, respectively. The median follow-up was 57 months (range 4-103) for x-CSI patients and 26 months (range 11-63) for p-CSI. Results: p-CSI patients lost less weight than x-CSI patients (1.2% vs 5.8%; P=.004), and less p-CSI patients had >5% weight loss compared with x-CSI (16% vs 64%; P=.004). p-CSI patients experienced less grade 2 nausea and vomiting compared with x-CSI (26% vs 71%; P=.004). Patients treated with x-CSI were more likely to have medical management of esophagitis than p-CSI patients (57% vs 5%, P<.001). p-CSI patients had a smaller reduction in peripheral white blood cells, hemoglobin, and platelets compared with x-CSI (white blood cells 46% vs 55%, P=.04; hemoglobin 88% vs 97%, P=.009; platelets 48% vs 65%, P=.05). Mean vertebral doses were significantly associated with reductions in blood counts. Conclusions: This report is the first analysis of clinical outcomes for adult medulloblastoma patients treated with p-CSI. Patients treated with p-CSI experienced less treatment-related morbidity including fewer acute gastrointestinal and hematologic toxicities.

  14. Poison Frog Colors Are Honest Signals of Toxicity, Particularly for Bird Predators. Author(s): Martine E. Maan and Molly E. Cummings

    E-Print Network [OSTI]

    Cummings, Molly E.

    Poison Frog Colors Are Honest Signals of Toxicity, Particularly for Bird Predators. Author://www.jstor.org #12;vol. 179, no. 1 the american naturalist january 2012 E-Article Poison Frog Colors Are Honest-polymorphic strawberry poison frog, Dendrobates pumilio. Using a mouse-based toxicity assay, we find extreme variation

  15. PURPOSE: This technical note describes the development of an alternative approach to evaluate chronic toxicity and the significance of contaminant bioaccumulation in dredged material assess-

    E-Print Network [OSTI]

    chronic toxicity and the significance of contaminant bioaccumulation in dredged material assess- ments) require that biological evaluations be conducted to determine the suitability of dredged material sediment, the biological tests are conducted to assess the toxicity and bioaccumulation of contami- nants in dredged

  16. Cellular Toxicity Induced by the Photorelease of a Caged Bioactive Molecule: Design of a Potential Dual-Action Ru(II) Complex

    E-Print Network [OSTI]

    Turro, Claudia

    ,*, and Claudia Turro*, Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio 43210 similar experimental conditions. The lack of toxicity imparted by 1 is explained by the exchange of only with visible light (irr 455 nm). A 34-fold increase in toxicity toward Hs-27 human skin cells was observed

  17. Space Science Technology Health General Sci-fi & Gaming Oddities International Business Politics Education Entertainment Sports Electronic Nose Sniffs Out Toxic Gases

    E-Print Network [OSTI]

    Suslick, Kenneth S.

    Education Entertainment Sports Electronic Nose Sniffs Out Toxic Gases Posted on: Sunday, 13 September 2009 detection of toxic industrial chemicals (TICs) that is simple, fast and inexpensive ­ and works identify and quantify the TICs in a matter of seconds." To create the sensor array, the researchers print

  18. In situ retreival of contaminants or other substances using a barrier system and leaching solutions and components, processes and methods relating thereto

    DOE Patents [OSTI]

    Nickelson, Reva A.; Walsh, Stephanie; Richardson, John G.; Dick, John R.; Sloan, Paul A.

    2005-06-28T23:59:59.000Z

    Processes and methods relating to treating contaminants and collecting desired substances from a zone of interest using subterranean collection and containment barriers. Tubular casings having interlock structures are used to create subterranean barriers for containing and treating buried waste and its effluents. The subterranean barrier includes an effluent collection system. Treatment solutions provided to the zone of interest pass therethrough and are collected by the barrier and treated or recovered, allowing on-site remediation. Barrier components may be used to in the treatment by collecting or removing contaminants or other materials from the zone of interest.

  19. When fish die, bacteria or the enzymes they produce invade the flesh of fish. This process produces toxic

    E-Print Network [OSTI]

    Michel, Howard E.

    ABSTRACT When fish die, bacteria or the enzymes they produce invade the flesh of fish. This process produces toxic compounds in the fish and the fish becomes spoiled. Fourier Transform Infrared spectroscopy neural network (ANN) for the development of an ANN based FT-IR Screening System for fish

  20. Failure to find aversive marking of toxic foods by Norway rats BENNETT G. GALEF, JR, SHANNON PRETTY & ELAINE E. WHISKIN

    E-Print Network [OSTI]

    Galef Jr., Bennett G.

    Failure to find aversive marking of toxic foods by Norway rats BENNETT G. GALEF, JR, SHANNON PRETTY, not where or what they avoid eating. We discuss possible ultimate explanations for this failure of naive a rat dam is eating may enter her amni- otic fluid, and fetal exposure to such cues may enhance pups