National Library of Energy BETA

Sample records for transportation workplace drug

  1. Policy on Drug-Free Workplace Policy on Drug-Free Workplace

    E-Print Network [OSTI]

    Sridhar, Srinivas

    Policy on Drug-Free Workplace 10/26/2014 Policy on Drug-Free Workplace I. Purpose and Scope responsible decision- making regarding the use of alcohol and other drugs. Northeastern strives to maintain drug use can create. Additionally, the University is committed to enforcing policies and laws relating

  2. Drug Free Workplace This notice is intended to meet the requirements of the Drug Free Workplace Act of 1988,

    E-Print Network [OSTI]

    Nicholson, Bruce J.

    Drug Free Workplace This notice is intended to meet the requirements of the Drug Free Workplace Act of 1988, United States Code Title 41, Chapter 81, and the Drug Free Schools and Communities Act Amendments revision date of September 1, 2016. Notice In accordance with the Drug Free Schools and Communities Act

  3. Drug-Free Federal Workplace Testing Implementation Program

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1988-07-29

    The order provides guidance and policy for the administration, application and implementation of the DOE Drug-free Federal Workplace Plan and other regulations that facilitate the maintenance of a drug-free Federal workplace through the establishment of programs to test for the use of illegal drugs. Chg 1, dated 8-21-92

  4. Drug-free Workplace Policy Responsible Administrative Unit: Human Resources

    E-Print Network [OSTI]

    Drug-free Workplace Policy Responsible Administrative Unit: Human Resources Policy Contact, students, and other individuals in our workplace and campus community. Alcohol abuse and drug use can pose.1 There are many risks associated with the use of illicit drugs and the abuse of alcohol, including physical

  5. Drug-Free Federal Workplace Testing Implementation Program

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2012-12-06

    The subject directive provides requirements and responsibilities for the implementation of a workplace program to test for the use of illegal drugs to facilitate the maintenance of a drug-free Federal workplace. In the course of the revision, the document number will change from DOE O 3792.3 to DOE O 343.1.

  6. Drug-Free Workplace Program UT-B Contracts Page 1 of 1

    E-Print Network [OSTI]

    Drug-Free Workplace Program UT-B Contracts Sep 2012 Page 1 of 1 drug-free-workplace-ext-sep12 DRUG, the Seller and its subcontractors working on the project site must maintain a drug-free workplace program. (B) If the Seller is an out-of-state entity, the Company may upon request allow a drug-free workplace

  7. Title: Drug and Alcohol Policies --Drug-Free Workplace Code: 1-300-020

    E-Print Network [OSTI]

    Huang, Jianyu

    -free workplace, and, in the case of grantees who are individuals, by requiring each individual to certify to receiving a contract or grant from a federal agency. All grantees who fail to meet the drug-free workplace of the Act. Grantees are not required to make a certification in order to continue receiving funds under

  8. Drug transport in brain via the cerebrospinal fluid

    E-Print Network [OSTI]

    Pardridge, William M

    2011-01-01

    diffusion. Drug transport into cerebrospinal fluid vs. brainDrug transport from blood to interstitial fluid (ISF) isDrug transport in brain via the cerebrospinal fluid William

  9. DRUG-FREE WORKPLACE NOTE: All residents/fellows are responsible for following the policy/procedure at each site

    E-Print Network [OSTI]

    Page 130 ` DRUG-FREE WORKPLACE NOTE: All residents/fellows are responsible for following the policy prohibits the unlawful possession, use or distribution of illicit drugs and alcohol on all premises related and efficiently. The presence of drugs or alcohol or the effect of these substances on residents/fellows would

  10. Workplace Charging Challenge Partner: U.S. Department of Transportation |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyofThe Hartford Workplace

  11. The Role of Transporters in the Pharmacokinetics of Orally Administered Drugs

    E-Print Network [OSTI]

    Shugarts, Sarah; Benet, Leslie Z.

    2009-01-01

    A, Benet LZ. Effects of drug transporters on volume of4. Mizuno N, Sugiyama Y. Drug transporters: their role andand development of new drugs. Drug Metab. Pharmacokinet.

  12. Skeletal muscle biomechanics drives intramuscular transport of locally delivered drugs

    E-Print Network [OSTI]

    Wu, Peter I-Kung

    2007-01-01

    Introduction: Effective local drug delivery to contractile tissues such as skeletal muscle requires a thorough understanding of the impact of mechanical loads on intramuscular pharmacokinetics. Current preparations for ...

  13. Mechanical loading impacts intramuscular drug transport : impact on local drug delivery

    E-Print Network [OSTI]

    Wu, Peter I-Kung

    2008-01-01

    Controlled-release drug-delivery systems enable efficient and defined administration of therapeutic agents to target tissues. However, ultimate drug distribution and pharmacologic effect are determined by target tissue ...

  14. Workplace Charging Challenge

    SciTech Connect (OSTI)

    2013-09-01

    Fact sheet about the EV Everywhere Workplace Charging Challenge which is to increase the number of American employers offering workplace charging by tenfold in the next five years.

  15. Workplace Charging Challenge: Sample Workplace Charging Policy

    Broader source: Energy.gov [DOE]

    Review the policy guidelines used by one Workplace Charging Challenge partner to keep their program running safe and successfully.

  16. SUPPLEMENTARY METHODS AND TABLES Drug transport from the blood into the lung tissue

    E-Print Network [OSTI]

    Kirschner, Denise

    1 SUPPLEMENTARY METHODS AND TABLES Drug transport from the blood into the lung tissue To study that enters the grid representing lung parenchyma via vascular sources, and diffuses among micro Once TNF inhibitors penetrate from blood into the lung tissue, they can bind TNF and thus block TNF

  17. Drug disposition and targeting: Transport across the blood-brain barrier

    E-Print Network [OSTI]

    Rochat, Bertrand; Audus, Kenneth L.

    1999-01-01

    the BBB. Neutral amino-acid carriers have proven to be capable of transporting many amino acids, drugs and endogenous compounds with similar stuctures. Leucine, cysteine, serine, alanine, phenylalanine, L-dopa, L-tryptophan, the alkylating agent... the carriers for opioids at the BBB have not been resolved. The possibility obviously exists, however, for the design and development of opioid peptide therapeutics that target BBB carriers and achieve improve brain delivery (Thomas et al., 1997). The last...

  18. Automakers and Workplace Charging

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Challenge Initiative Arguably the most important infrastructure strategy to accelerate adoption of PEVs. Why are we doing Workplace Charging? * PEV Market Growth - Critical now...

  19. Workplace Charging Challenge

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    EV Everywhere Workplace Charging Challenge, committing to install charging for plug-in electric vehicles (PEVs) at their worksites. By taking on this Challenge, they are helping...

  20. Plug-In Electric Vehicle Handbook for Workplace Charging Hosts

    SciTech Connect (OSTI)

    2013-08-01

    Plug-in electric vehicles (PEVs) have immense potential for increasing the country's energy, economic, and environmental security, and they will play a key role in the future of U.S. transportation. By providing PEV charging at the workplace, employers are perfectly positioned to contribute to and benefit from the electrification of transportation. This handbook answers basic questions about PEVs and charging equipment, helps employers assess whether to offer workplace charging for employees, and outlines important steps for implementation.

  1. Workplace Charging Challenge Progress Update 2014: Employers...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Workplace Charging Challenge Progress Update 2014: Employers Take Charge Workplace Charging Challenge Progress Update 2014: Employers Take Charge The Workplace Charging Challenge...

  2. Trends in Workplace Charging

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Donofrio Ford Motor Company Trends in Workplace Charging Est EV NA NA approx 21 70-100 Miles: What Types of Chargers are Being Used? Considerations for Campus Installations *...

  3. Validation of in vitro cell models used in drug metabolism and transport studies; genotyping of cytochrome P450, phase II enzymes and drug transporter polymorphisms in the human hepatoma (HepG2), ovarian carcinoma (IGROV-1) and colon carcinoma (CaCo-2, LS180) cell lines

    SciTech Connect (OSTI)

    Brandon, Esther F.A.; Bosch, Tessa M.; Deenen, Maarten J.; Levink, Rianne; Wal, Everdina van der; Meerveld, Joyce B.M. van; Bijl, Monique; Beijnen, Jos H. |; Schellens, Jan H.M. |; Meijerman, Irma . E-mail: I.Meijerman@pharm.uu.nl

    2006-02-15

    Human cell lines are often used for in vitro biotransformation and transport studies of drugs. In vivo, genetic polymorphisms have been identified in drug-metabolizing enzymes and ABC-drug transporters leading to altered enzyme activity, or a change in the inducibility of these enzymes. These genetic polymorphisms could also influence the outcome of studies using human cell lines. Therefore, the aim of our study was to pharmacogenotype four cell lines frequently used in drug metabolism and transport studies, HepG2, IGROV-1, CaCo-2 and LS180, for genetic polymorphisms in biotransformation enzymes and drug transporters. The results indicate that, despite the presence of some genetic polymorphisms, no real effects influencing the activity of metabolizing enzymes or drug transporters in the investigated cell lines are expected. However, this characterization will be an aid in the interpretation of the results of biotransformation and transport studies using these in vitro cell models.

  4. Workplace Charging Challenge Partner: University of Maryland...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Maryland Baltimore Washington Medical Center Workplace Charging Challenge Partner: University of Maryland Baltimore Washington Medical Center Workplace Charging Challenge Partner:...

  5. Workplace Charging Challenge Partner: Bosch Automotive Service...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Bosch Automotive Service Solutions, Inc. Workplace Charging Challenge Partner: Bosch Automotive Service Solutions, Inc. Workplace Charging Challenge Partner: Bosch Automotive...

  6. Workplace Charging Challenge Partner: University of California...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    California, Santa Barbara Workplace Charging Challenge Partner: University of California, Santa Barbara Workplace Charging Challenge Partner: University of California, Santa...

  7. Experimental and theoretical investigation of the effects of low-frequency sonophoresis on transdermal drug transport

    E-Print Network [OSTI]

    Tang, Hua, 1972-

    2002-01-01

    Transdermal drug delivery offers many advantages over traditional drug administration methods such as injections and oral delivery, including increased patient compliance, and avoiding first-pass effects. However, due to ...

  8. WORKPLACE GUIDES GLOBAL WORKING

    E-Print Network [OSTI]

    Roelleke, Thomas

    of Stonewall good practice publications ­ profiles some of the employers paving the way for gay staff to work do arise. This guide provides clear, practical tips on how gay employees can access internationalWORKPLACE GUIDES GLOBAL WORKING Supporting lesbian, gay and bisexual staff on overseas assignments

  9. Automakers and Workplace Charging

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based Fuels Research atDepartmentAudits and6AuidtWorkplace Charging Summit

  10. Prediction of multi-drug resistance transporters using a novel sequence analysis method [version 2; referees: 2 approved

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    McDermott, Jason E.; Bruillard, Paul; Overall, Christopher C.; Gosink, Luke; Lindemann, Stephen R.

    2015-03-09

    There are many examples of groups of proteins that have similar function, but the determinants of functional specificity may be hidden by lack of sequencesimilarity, or by large groups of similar sequences with different functions. Transporters are one such protein group in that the general function, transport, can be easily inferred from the sequence, but the substrate specificity can be impossible to predict from sequence with current methods. In this paper we describe a linguistic-based approach to identify functional patterns from groups of unaligned protein sequences and its application to predict multi-drug resistance transporters (MDRs) from bacteria. We first showmore »that our method can recreate known patterns from PROSITE for several motifs from unaligned sequences. We then show that the method, MDRpred, can predict MDRs with greater accuracy and positive predictive value than a collection of currently available family-based models from the Pfam database. Finally, we apply MDRpred to a large collection of protein sequences from an environmental microbiome study to make novel predictions about drug resistance in a potential environmental reservoir.« less

  11. Generation Y in the Workplace 

    E-Print Network [OSTI]

    Brown, Sky; Carter, Britt; Collins, Michael; Gallerson, Christopher; Giffin, Grady; Greer, Jon; Griffith, Ray; Johnson, Emily; Richardson, Kate

    2009-01-01

    stream_source_info 2009GenerationYintheWorkplace.pdf.txt stream_content_type text/plain stream_size 155407 Content-Encoding ISO-8859-1 stream_name 2009GenerationYintheWorkplace.pdf.txt Content-Type text/plain; charset=ISO-8859...-1 Generation Y in the Workplace Sky Brown Britt Carter Michael Collins Christopher Gallerson Grady Giffin Jon Greer Ray Griffith Emily Johnson Kate Richardson Faculty Advisor: Dr. Domonic Bearfield i Executive Summary...

  12. Alcohol and Other Drugs -1 -Approved: 05/09/2014 Alcohol and Other Drugs

    E-Print Network [OSTI]

    Hammack, Richard

    Alcohol and Other Drugs - 1 - Approved: 05/09/2014 Alcohol and Other Drugs Policy Type: Board with the federal Drug Free Workplace Act of 1988, the federal Drug Free Schools and Communities Act of 1989, and the Commonwealth of Virginia's Policy on Alcohol and Other Drugs (AOD), it is the policy of Virginia Commonwealth

  13. Interagency ADR Workplace Section Education Programs

    Broader source: Energy.gov [DOE]

    The Interagency Alternative Dispute Resolution Working Group (IADRWG) Workplace Conflict Management Section (“Workplace Section”) provides guidance on “best practices” in ADR program development,...

  14. Workplace Charging Challenge Progress Update 2014

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    4 Progress Update 2014: Employers Take Charge Available at energy.goveerevehiclesev-everywhere-workplace-charging-challenge Workplace Charging Challenge 5 Cumulative...

  15. Workplace Charging Challenge Partner: Vermont Energy Investment...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    More Information VEIC's Mission Workplace Charging News June 23, 2014 VEIC now an EV Everywhere Workplace Charging Challenge Partner The use of Electric Vehicles (EVs) is...

  16. Workplace Charging Challenge Partner: Purchase College, State...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Purchase College, State University of New York Workplace Charging Challenge Partner: Purchase College, State University of New York Workplace Charging Challenge Partner: Purchase...

  17. In vitro intestinal transport of a poorly aqueous soluble drug and p-glycoprotein efflux using biorelevant medium simulating the intestinal fluids

    E-Print Network [OSTI]

    Lind, M. L.; Jacobsen, J.; Holm, R.; Mü llertz, A.

    2006-10-27

    In vitro intestinal transport of a poorly aqueous soluble drug and efflux using biorelevant medium simulating the intestinal fluids Marianne L. Lind 1,3 , Jette Jacobsen 1 , Ren? Holm 2 , Anette M?llertz 1 1 Department of Pharmaceutics... of the Caco-2 cell culture model, biorelevant media (BM) simulating the intestinal fluids have been tested for compatibility with the model (1). Use of BM in the Caco-2 cell model has previously been shown to affect transport of drugs (2). Poorly aqueous...

  18. Workplace Charging Challenge Summit 2014: Session 1, Track B...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Technologies Office Merit Review 2015: Lessons Learned about Workplace Charging in The EV Project Workplace Charging Challenge Summit 2014: Session 3, Track A Workplace Charging...

  19. Workplace Charging Challenge Partner: Sierra Nevada Brewing Co...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Workplace Charging Challenge Partner: Sierra Nevada Brewing Co. Workplace Charging Challenge Partner: Sierra Nevada Brewing Co. Workplace Charging Challenge Partner: Sierra Nevada...

  20. Workplace Charging Challenge Partner: Lawrence Berkeley National...

    Broader source: Energy.gov (indexed) [DOE]

    even more to do so, Berkeley Lab has announced that it will start offering workplace EV charging. The workplace charging is just one of several initiatives Berkeley Lab is...

  1. Workplace policies and practices of care 

    E-Print Network [OSTI]

    McKie, Linda; Bowby, Sophie; Hogg, Gill; Smith, Andrew

    Workplace policies and practices of care are designed to support workers’ caring responsibilities outside of the workplace as well as their general wellbeing. A previous CRFR briefing (McKie et al 2004) detailed the ...

  2. Virtual Desktop Infrastructure (VDI) and Citrix Workplace

    Broader source: Energy.gov [DOE]

    For questions or concerns related to VDI or Workplace, contact the EITS Service Desk at 301-903-2500.

  3. WORKPLACE HAZARD ASSESSMENT Location: Task

    E-Print Network [OSTI]

    Rubloff, Gary W.

    WORKPLACE HAZARD ASSESSMENT Location: Task: Performed by: Date: This form may be used as an aid in performing hazard assessment. Review listed hazard classifications, identify all hazards, possible hazards and their sources. Hazard classification listing is not intended to be complete but is provided as a guide

  4. Contractor Workplace Substance Abuse Program at DOE Sites (10 CFR 707)

    Broader source: Energy.gov [DOE]

    This rule establishes policies, criteria, and procedures for developing and implementing programs to maintain a workplace free from the use of illegal drugs. It applies to DOE contractors performing work at sites owned or controlled by DOE and to individuals with unescorted access to the control areas of certain DOE reactors.

  5. POLICY STATEMENT ON DRUG-FREE CAMPUS*

    E-Print Network [OSTI]

    Karsai, Istvan

    11 POLICY STATEMENT ON DRUG-FREE CAMPUS* It is the policy of ETSU that the unlawful manufacture, distribution, possession, use of alcohol and illicit drugs on the ETSU campus, in the workplace (on or off campus), on property owned or controlled by ETSU, or as part of any activity of ETSU is strictly

  6. Workplace Charging at Leased Facilities

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyofTheDepartment of Energy WORKPLACE

  7. U.S. Department of Energy's EV Everywhere Workplace Charging Challenge, Mid-Program Review: Employees Plug In

    SciTech Connect (OSTI)

    2015-12-01

    This Program Review takes an unprecedented look at the state of workplace charging in the United States -- a report made possible by U.S. Department of Energy leadership and valuable support from our partners as they share their progress in developing robust workplace charging programs. Through the Workplace Charging Challenge, more than 250 participants are accelerating the development the nation's worksite PEV charging infrastructure and are supporting cleaner, more convenient transportation options within their communities. Challenge partners are currently providing access to PEV charging stations at more than 440 worksites across the country and are influencing countless other organizations to do the same.

  8. Bringing Your Workplace Charging Story to Life

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    charging workshops * Other community events 10 Shannon.shea@ee.doe.gov http:energy.goveerevehiclesvehicle-technologies-office-ev-everywhere- workplace-charging-challenge 11...

  9. HQ Mediation Program for Workplace Conflicts | Department of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Program for Workplace Conflicts The DOE Headquarters Mediation Program began in 1995. We believe that most workplace conflicts are based on miscommunication, and that it is...

  10. EV Everywhere Workplace Charging Challenge | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Plug-in Electric Vehicles & Batteries EV Everywhere Workplace Charging Challenge EV Everywhere Workplace Charging Challenge Join the...

  11. Workplace Charging Challenge Partner: University at Albany: State...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    at Albany: State University of New York Workplace Charging Challenge Partner: University at Albany: State University of New York Workplace Charging Challenge Partner: University at...

  12. Transportation

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservationBio-Inspired SolarAbout / Transforming Y-12Capacity-Forum Sign InTransportation

  13. Fact #857 January 26, 2015 Number of Partner Workplaces Offering...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    these partners in August 2014 showed that the availability of workplace electric vehicle (EV) charging increased to about 275 workplaces in 2014, a 345% growth from 2011. Of those...

  14. Community and collaboration : new shared workplaces for evolving work practices

    E-Print Network [OSTI]

    Bates, Timothy W. (Timothy Waterbury)

    2011-01-01

    The 'collaborative community workplace' is a growing type of shared, flexible workplace that has emerged in recent years in response to a growing need for productive workspaces for mobile, distributed, and independent ...

  15. Workplace Charging Challenge Employer Workshop Best Practices Webinar

    Broader source: Energy.gov [DOE]

    Learn about the experiences of four event hosts and how they planned, organized, and administered successful workplace charging events.

  16. WORKPLACE VIOLENCE PREVENTION PROGRAM Health and Safety

    E-Print Network [OSTI]

    " if the worker could be expected to encounter the person in the course of his/her work and there is a risk of this program is to implement the workplace violence policy (OHS-10-003) by ensuring a safe learning and work and Safety Act. This is accomplished through the following: Risk assessments Control of general risk

  17. Workplace Training Module: Enhancing Ecotourism Business Performance

    E-Print Network [OSTI]

    Workplace Training Module: Enhancing Ecotourism Business Performance (Level 5 ­ 10 credits as part of university course) Prescriptor This training module forms part of a broader qualification focused for ecotourism in the region Learning and teaching strategies This training module will be taught

  18. Psychologically Healthy Workplace Practices = Good Business

    Broader source: Energy.gov [DOE]

    Creating a psychologically healthy workplace is not just the right thing to do for employees; it’s also the smart thing to do for an organization’s financial well being and productivity. A small investment in psychologically healthy work practices can pay big dividends in years to come.

  19. Energy Department Welcomes Department of Transportation as New Workplace

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuels Data Center HomeVehicleDepartment ofGraphicsPowerDepartmentIowa Plant

  20. Antiarrhythmic Drugs

    E-Print Network [OSTI]

    Abbott, GW; Levi, R

    2012-01-01

    of beta blockers: from antianginal drugs to ligand-directedmechanisms of gating and drug block of sodium channels.Roden DM. Antiarrhythmic drugs: past, present and future. J

  1. Workplace Charging Challenge Partner: Northwest Evaluation Association

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyof Energy JLANetApp Workplace

  2. Workplace Charging Challenge Partner: University of Connecticut |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyofThe Hartford WorkplaceCenterBarbara

  3. A Holistic Approach to the Sustainable Workplace of the Future 

    E-Print Network [OSTI]

    Andersen, S. E.

    2008-01-01

    of the future. In his presentation, Mr. Andersen will be focusing on: Buildings and the Environment: Sustainable Development - many new sustainable building are being designed and built with a focus only on their physical and environment impact... as criteria to achieve sustainable development. However, these criteria alone cannot guarantee a good sustainable workplace. Buildings and People: The Integrated Workplace - many new workplace design projects are being designed and built with a focus...

  4. Program Review, Workplace Inspections, Hazards Analysis And Abatement

    Broader source: Energy.gov [DOE]

    This document provides guidance information and suggested procedures for performing program review, workplace inspections, hazards analysis, and abatement, successfully at DOE Federal employee worksites.

  5. Workplace Charging Challenge: Press Release template for Ambassadors

    Broader source: Energy.gov [DOE]

    An editable press release that Ambassador organizations can use to announce their and local Partners' participation in the EV Everywhere Workplace Charging Challenge

  6. Workplace Charging Challenge: Press Release template for Clean Cities coordinators

    Broader source: Energy.gov [DOE]

    An editable press release that Clean Cities coordinators can use to announce local Partners' participation in the EV Everywhere Workplace Charging Challenge

  7. DIRECT COSTS OF DISABLING WORKPLACE INJURIES GROW 2.5 PERCENT

    Broader source: Energy.gov [DOE]

    April 7, 2003 Annual Liberty Mutual Workplace Safety Index Shows Direct Costs of the Three Leading Causes of Workplace Incidents Grew Significantly Faster...

  8. Preventing and Responding to All Forms of Violence in the Workplace...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    P 444.1, Preventing and Responding to All Forms of Violence in the Workplace (Informational Purposes Only) by Beau Newman Functional areas: Workplace Violence, Employee Safety This...

  9. April 10, 2014- “Workplace Disruptions, Reorganizations, and ‘Change Fatigue’: Can ADR Support Resilience?”

    Broader source: Energy.gov [DOE]

    April 10, 2014 - “Workplace Disruptions, Reorganizations, and ‘Change Fatigue’: Can ADR Support Resilience?”

  10. Workers’ Involvement at the workplace and Job Quality in Europe 

    E-Print Network [OSTI]

    González, María C

    2009-01-01

    The paper focuses on workplace practices aimed at increasing workers’ direct voice, a job quality dimension in the European Employment Strategy for which there are no agreed indicators. It offers an analysis of the theories, ...

  11. Workplace Charging Challenge Mid-Program Review: Promising Progress...

    Broader source: Energy.gov (indexed) [DOE]

    in more than 600 workplaces with over 5,500 charging stations accessible to nearly 1 million employees. Today, more than 9,000 PEV-driving employees are charging at these...

  12. Vehicle Technologies Office: Workplace Charging Challenge 2015 Annual Survey Webinar

    Broader source: Energy.gov [DOE]

    This webinar provides an update on the Workplace Charging Challenge initiative, describes the survey, discusses why the Survey input is essential, and walks through the log-in and submission process.

  13. Workplace Substance Abuse Programs at DOE Sites UT-B Contracts Div Page 1 of 1

    E-Print Network [OSTI]

    Workplace Substance Abuse Programs at DOE Sites UT-B Contracts Div July 2006 Page 1 of 1 work-place-sub-abuse-ext-july06.doc WORKPLACE SUBSTANCE ABUSE PROGRAMS AT DOE SITES (July 2006) (a) The Seller shall, consistent with 10 CFR part 707, Workplace Substance Abuse Programs at DOE Sites, incorporated herein by reference

  14. "We are not in the loop": Resource Wastage and Conservation Attitude of Employees in Indian Workplace

    E-Print Network [OSTI]

    Toronto, University of

    . INTRODUCTION Global consumption of energy, water, fuel and trees has been increasing rapidly. The supply cannot and wastage, including energy, water, fuel, trees, and food, in an Indian workplace. Factors that acted, to facilitate conservation at workplaces. Author Keywords Sustainability, Energy, Workplace, Developing World

  15. Short-term calorie restriction feminizes the mRNA profiles of drug metabolizing enzymes and transporters in livers of mice

    SciTech Connect (OSTI)

    Fu, Zidong Donna; Klaassen, Curtis D.

    2014-01-01

    Calorie restriction (CR) is one of the most effective anti-aging interventions in mammals. A modern theory suggests that aging results from a decline in detoxification capabilities and thus accumulation of damaged macromolecules. The present study aimed to determine how short-term CR alters mRNA profiles of genes that encode metabolism and detoxification machinery in the liver. Male C57BL/6 mice were fed CR (0, 15, 30, or 40%) diets for one month, followed by mRNA quantification of 98 xenobiotic processing genes (XPGs) in the liver, including 7 uptake transporters, 39 phase-I enzymes, 37 phase-II enzymes, 10 efflux transporters, and 5 transcription factors. In general, 15% CR did not alter mRNAs of most XPGs, whereas 30 and 40% CR altered over half of the XPGs (32 increased and 29 decreased). CR up-regulated some phase-I enzymes (fold increase), such as Cyp4a14 (12), Por (2.3), Nqo1 (1.4), Fmo2 (5.4), and Fmo3 (346), and numerous number of phase-II enzymes, such as Sult1a1 (1.2), Sult1d1 (2.0), Sult1e1 (33), Sult3a1 (2.2), Gsta4 (1.3), Gstm2 (1.3), Gstm3 (1.7), and Mgst3 (2.2). CR feminized the mRNA profiles of 32 XPGs in livers of male mice. For instance, CR decreased the male-predominantly expressed Oatp1a1 (97%) and increased the female-predominantly expressed Oatp1a4 (11). In conclusion, short-term CR alters the mRNA levels of over half of the 98 XPGs quantified in livers of male mice, and over half of these alterations appear to be due to feminization of the liver. - Highlights: • Utilized a graded CR model in male mice • The mRNA profiles of xenobiotic processing genes (XPGs) in liver were investigated. • CR up-regulates many phase-II enzymes. • CR tends to feminize the mRNA profiles of XPGs.

  16. Experimental study of nuclear workplace aerosol samplers 

    E-Print Network [OSTI]

    Parulian, Antony

    1995-01-01

    consists of an inlet-elbow, a transport line, and a EL-900 CAM prototype manufactured by EG&G. Results show that only 12% of 10 []m aerodynamic diameter (AD) aerosol particles penetrate through the complete sampling system when it is operated at flow rate...

  17. Sustainable Transport

    E-Print Network [OSTI]

    Webber, Melvin

    2006-01-01

    THOUGHT PIECE Sustainable Transport by Melvin M. Webberwant to sustain any mode of transport only if we judge it todraconian in rejecting transport modes that have failed in

  18. Workplace Charging Challenge Partner: Cigna | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergy Safely TearEnergyCigna Workplace Charging

  19. Workplace Charging Challenge Partner: Cisco Systems, Inc. | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergy Safely TearEnergyCigna Workplace

  20. Workplace Charging Challenge Partner: JLA Public Involvement | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyof Energy JLA Public Involvement Workplace

  1. Workplace Charging Challenge Partner: The Hartford | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyofThe Hartford Workplace Charging Challenge

  2. Workplace Charging Challenge Partner: The University of Rhode Island |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyofThe Hartford Workplace Charging

  3. Workplace Charging Challenge Partner: The Venetian and The Palazzo |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyofThe Hartford Workplace ChargingDepartment of

  4. Workplace Charging Challenge Partner: Township High School District 214 |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyofThe Hartford Workplace ChargingDepartment

  5. Workplace Charging Challenge Partner: UCLA Smart Grid Energy Research

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyofThe Hartford WorkplaceCenter (SMERC) |

  6. Workplace Charging Challenge Partner: Ulster County | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyofThe Hartford WorkplaceCenter (SMERC) |Ulster

  7. Workplace Charging Challenge Partner: University at Albany: State

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyofThe Hartford WorkplaceCenter (SMERC)

  8. Workplace Charging Challenge Partner: University of Alaska Southeast |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyofThe Hartford WorkplaceCenter

  9. Workplace Charging Challenge Partner: University of California, Santa

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyofThe Hartford WorkplaceCenterBarbara |

  10. Workplace Charging Challenge Partner: University of Hawaii at Hilo |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyofThe Hartford WorkplaceCenterBarbaraDepartment

  11. Workplace Charging Challenge Partner: Unum Group | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyofThe HartfordUnum Group Workplace Charging

  12. Workplace Charging Challenge Partner: Utilidata | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyofThe HartfordUnum Group Workplace

  13. Workplace Charging Challenge Partner: Xcel Energy | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyofThe HartfordUnumXcel Energy Workplace

  14. ADA Requirements for Workplace Charging Installation | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative FuelsofProgram:Y-12 Beta-3 Racetracks25 AMOSystemADA Requirements for Workplace

  15. Workplace Charging Success: Zappos.com | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative FuelsofProgram: Report1538-1950DepartmentWaveWind(NREL)Zappos.com Workplace Charging

  16. Workplace Charging Success: lynda.com | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative FuelsofProgram: Report1538-1950DepartmentWaveWind(NREL)Zappos.com Workplace

  17. NEW - DOE P 444.1, Preventing and Responding to all Forms of Violence in the Workplace

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    The Policy states DOE's expectation regarding the prevention of all forms of violence (to include physical and psychological) within the DOE workplace and providing support and assistance to employees whose lives are affected by workplace violence.

  18. Fact #857 January 26, 2015 Number of Partner Workplaces Offering Electric Vehicle Charging More Than Tripled Since 2011 – Dataset

    Broader source: Energy.gov [DOE]

    Excel file with dataset for Number of Partner Workplaces Offering Electric Vehicle Charging More Than Tripled Since 2011

  19. THE CITY UNIVERSITY OF NEW YORK THE GRADUATE CENTER WORKPLACE VIOLENCE PREVENTION PROGRAM

    E-Print Network [OSTI]

    Artemov, Sergei N.

    . Murphy Institute for Worker Education and Labor Studies, adopts the following as its Workplace Violence at the Colleges. 4. Risk Assessment and Evaluation Process a. On an annual basis, the WVAT will: i. Examine evaluation of the College's workplace to determine the presence of factors that may place employees at risk

  20. Preventing and Responding to all Forms of Violence in the Workplace

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2014-11-06

    The Policy states DOE's expectation regarding the prevention of all forms of violence (to include physical and psychological) within the DOE workplace and providing support and assistance to employees whose lives are affected by workplace violence. Does not cancel/supersede other directives.

  1. Exploring transport and phase behavior in nanoporous carbon materials

    E-Print Network [OSTI]

    Shimizu, Steven (Steven Franklin Esau)

    2015-01-01

    Understanding transport and phase behavior in nanopores has a substantial impact on applications involving membrane fabrication, single-molecule detection, oil reservoir modeling, and drug delivery. While transport and ...

  2. Workplace Charging Challenge Partner: City of Auburn Hills | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergy Safely TearEnergyCigna WorkplaceEnergy

  3. Workplace Charging Challenge Partner: ClipperCreek, Inc. | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergy SafelyEnergy ClipperCreek, Inc. Workplace

  4. Workplace Charging Challenge Partner: NetApp | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyof Energy JLANetApp Workplace Charging

  5. Workplace Charging Challenge Partner: New York Power Authority | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyof Energy JLANetApp Workplace Chargingof

  6. Workplace Charging Challenge Partner: OSRAM SYLVANIA | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyof Energy JLANetApp WorkplaceOSRAM SYLVANIA

  7. Workplace Charging Challenge Partner: Odell Brewing Co. | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyof Energy JLANetApp WorkplaceOSRAM

  8. Workplace Charging Challenge Partner: Oregon State University | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyof Energy JLANetApp WorkplaceOSRAMof

  9. Workplace Charging Challenge Partner: Organic Valley | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyof Energy JLANetApp WorkplaceOSRAMofOrganic

  10. Workplace Charging Challenge Partner: Utah Paperbox | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyofThe HartfordUnum Group Workplace ChargingUtah

  11. Workplace Charging Challenge Partner: Verizon | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyofThe HartfordUnum Group WorkplaceVerizon

  12. Workplace Charging Challenge Partner: Vermont Energy Investment Corporation

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyofThe HartfordUnum Group WorkplaceVerizon|

  13. Workplace Charging Challenge Partner: DIRECTV | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative FuelsofProgram: Report1538-1950DepartmentWaveWind ProgramWork PlanDIRECTV Workplace

  14. DRUG DELIVERY IN BIOLOGICAL TISSUES: AN APPLICATION TO THE ELUTING STENT

    E-Print Network [OSTI]

    Pontrelli, Giuseppe

    DRUG DELIVERY IN BIOLOGICAL TISSUES: AN APPLICATION TO THE ELUTING STENT G. Pontrelli1 , F. de Monte2 , M. Prosi3 1. ABSTRACT The drug diffusion process through an arterial eluting stent is studied and a quantitative description for drug transport to evaluate feasibility of new drug delivery strategies

  15. DEVELOPMENTAL REGULATION OF THE DRUG-PROCESSING GENOME IN MOUSE LIVER

    E-Print Network [OSTI]

    Cui, Yue

    2010-07-29

    Despite the recent progress in understanding the expression patterns and regulatory mechanisms of drug-processing genes, namely phase-I and -II drug metabolizing enzymes and transporters in adults, very little is known of ...

  16. Drug Retention Times

    SciTech Connect (OSTI)

    Center for Human Reliability Studies

    2007-05-01

    The purpose of this monograph is to provide information on drug retention times in the human body. The information provided is based on plausible illegal drug use activities that might be engaged in by a recreational drug user

  17. Drug Retention Times

    SciTech Connect (OSTI)

    Center for Human Reliability Studies

    2007-05-01

    The purpose of this monograph is to provide information on drug retention times in the human body. The information provided is based on plausible illegal drug use activities that might be engaged in by a recreational drug user.

  18. Drug interactions evaluation: An integrated part of risk assessment of therapeutics

    SciTech Connect (OSTI)

    Zhang, Lei; Reynolds, Kellie S.; Zhao, Ping [Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Building 51, Room 3188, 10903 New Hampshire Avenue, Silver Spring, MD 20993 (United States); Huang, Shiew-Mei, E-mail: shiewmei.huang@fda.hhs.go [Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Building 51, Room 3188, 10903 New Hampshire Avenue, Silver Spring, MD 20993 (United States)

    2010-03-01

    Pharmacokinetic drug interactions can lead to serious adverse events or decreased drug efficacy. The evaluation of a new molecular entity's (NME's) drug-drug interaction potential is an integral part of risk assessment during drug development and regulatory review. Alteration of activities of enzymes or transporters involved in the absorption, distribution, metabolism, or excretion of a new molecular entity by concomitant drugs may alter drug exposure, which can impact response (safety or efficacy). The recent Food and Drug Administration (FDA) draft drug interaction guidance ( (http://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/ucm072101.pdf)) highlights the methodologies and criteria that may be used to guide drug interaction evaluation by industry and regulatory agencies and to construct informative labeling for health practitioner and patients. In addition, the Food and Drug Administration established a 'Drug Development and Drug Interactions' website to provide up-to-date information regarding evaluation of drug interactions ( (http://www.fda.gov/Drugs/DevelopmentApprovalProcess/DevelopmentResources/DrugInteractionsLabeling/ucm080499.htm)). This review summarizes key elements in the FDA drug interaction guidance and new scientific developments that can guide the evaluation of drug-drug interactions during the drug development process.

  19. Non-Tracial Free Transport and Applications

    E-Print Network [OSTI]

    Nelson, Brent Andrew

    2015-01-01

    tracial transport . . . . . . . . . . . . . . . . . . . .the transport element . . . . . . . . . . . . . .Free Transport . . . . . . . . . . . .

  20. Commissioning Lessons from Study of the Advanced Systems at the CMU Intelligent Workplace 

    E-Print Network [OSTI]

    Claridge, D. E.; Gong, X.

    2008-01-01

    A detailed study has been conducted of the performance of several innovative aspects of the Intelligent Workplace (IW) at Carnegie Mellon University, a low energy consumption building that uses radiant heating, cooling and a desiccant ventilation...

  1. Managing work-life policies in the European workplace: explorations for future research 

    E-Print Network [OSTI]

    den Dulk, Laura; Peper, Bram

    2009-01-01

    In this paper we focus on the implementation and management of work-life policies in the workplace and the key role of managers in this context. We review the existing literature, enabling us to set a research agenda focused ...

  2. Guide on Preventing and Responding to All Forms of Violence in the Workplace

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2015-04-22

    This guide is a broad overview of the basic tools for development of site specific procedures for responding to workplace violence. Supports implementation of DOE P 444.1. Does not cancel/supersede other directives.

  3. Individual innovation in the workplace: the role of performance and image outcome expectations 

    E-Print Network [OSTI]

    Yuan, Feirong

    2009-05-15

    Why do people engage in innovative behavior in the workplace? More specifically, what motivational reasons affect an employee?s decision to introduce new product ideas, apply new work methods, and suggest new ways to achieve objectives? Based...

  4. Exanthematous allergic drug reactions due to four chemically unrelated drugs

    E-Print Network [OSTI]

    Gupta, Ramji; Gupta, Sameer

    2008-01-01

    16. Lachgar T, Touil Y. The drug hypersensitivity syndromeW, Bircher A, Romano A et al. Drug provocation testing inthe diagnosis of drug hypersensitivity reactions: general

  5. Resistance to currently used drugs is a serious problem in most fields of antimicrobial chemotherapy. Crossresistance

    E-Print Network [OSTI]

    Schnaufer, Achim

    Resistance to currently used drugs is a serious problem in most fields of antimicrobial chemotherapy. Crossresistance between two of the major classes of drug used in the treat- ment of African as a result of alterations in an unusual adenosine transporter involved in the uptake of these drugs. African

  6. Trip rate comparison of workplace and household surveys 

    E-Print Network [OSTI]

    Endres, Stephen Michael

    1997-01-01

    Travel surveys are the foundation of traffic predictions. From travel surveys, the general public's traveling characteristics are obtained. The traveling characteristics of people allow transportation planners, through computer modeling, to predict...

  7. Adolescent drug abuse - Awareness & prevention

    E-Print Network [OSTI]

    Chakravarthy, Bharath; Shah, Shyam; Lotfipour, Shahram

    2013-01-01

    and the risk of illicit drug use: the Adverse Childhoodalcohol, tobacco and other drug use. Int Rev Psychiatry.therapy for adolescent drug abuse. J Clin Child Psychol.

  8. Sustainable Transportation

    SciTech Connect (OSTI)

    2012-09-01

    This document highlights DOE's Office of Energy Efficiency and Renewable Energy's advancements in transportation technologies, alternative fuels, and fuel cell technologies.

  9. Orphanet Berichtsreihe Orphan Drugs Datenerhebung

    E-Print Network [OSTI]

    Manstein, Dietmar J.

    Orphanet Berichtsreihe Orphan Drugs Datenerhebung Verzeichnis der in Europa zugelassenen Orphan Drugs Mit europäischer Orphan-Drug-Designation und europäischer Marktzulassung* Mit europäischer Marktzulassung* ohne vorherige Orphan-Drug-Designation *Zentrales Zulassungsverfahren der Europäischen

  10. Transportation Plan 

    E-Print Network [OSTI]

    Boreo, Andrea; Li, Wei; Wunnenbuger, Douglas; Giusti, Cecilia; Cooper, John T.; Masterson, Jaimie

    2015-01-01

    Mobility throughout a community ensures freedom of movement and enhances quality of life. Traffic congestion, pollution, urban sprawl, social exclusion, safety and health can decrease mobility and should be a part of a sustainable transportation...

  11. electrifyingthefuture transportation

    E-Print Network [OSTI]

    Birmingham, University of

    programme of electrification and the potential introduction of diesel hybrids. The Department for Transport vehicles Wind turbine systems Industrial equipment The lab has full ethernet capability which will enable

  12. Campus Climate: Behaviors within a workplace or learning environment, ranging from subtle to cumu-

    E-Print Network [OSTI]

    Salvaggio, Carl

    Enhancing Department Climate Campus Climate: Behaviors within a workplace or learning environment safe, listened to, valued, and treated fairly and with respect. 1 Climate: The atmosphere or ambience of an orga- nization as perceived by its members. An organiza- tion's climate is reflected in its structures

  13. Performance Modeling of a Solar Driven Absorption Cooling System for Carnegie Mellon University's Intelligent Workplace 

    E-Print Network [OSTI]

    Masson, S. V.; Qu, M.; Archer, D. H.

    2006-01-01

    The Robert L. Preger Intelligent Workplace (IW) is a 650 m2 (7,000 ft2) living laboratory of office space at Carnegie Mellon University (Pittsburgh, PA). The IW is involved in a project to develop, install, and test an ...

  14. Guide on Preventing and Responding to All Forms of Violence in the Workplace

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2014-10-21

    To ensure all sites have the tools to implement processes, we have created this guide. Each site is expected to develop its own site specific set of procedures/process to implement DOE Policy 444.1 Preventing and Responding to all forms of violence in the Workplace.

  15. The living workplace : a conscious work environment for a small publishing company

    E-Print Network [OSTI]

    Berg, Richard Carl

    1986-01-01

    This thesis is about the oneness of working and living, and about the making of workplaces that support and encourage the idea that one's work can be an integral part of one's life. The opening position is that there is a ...

  16. Complete Policy Title: Policy Number (if applicable): Violence in the Workplace -

    E-Print Network [OSTI]

    Thompson, Michael

    Complete Policy Title: Policy Number (if applicable): Violence in the Workplace - McMaster University Policy on Approved by: Date of Most Recent Approval: Senate June 2, 2010 Board of Governors June 17, 2010 Date of Original Approval: Supersedes/Amends Policy dated: June 2, 2010 Responsible

  17. Complex workplace radiation fields at European high-energy accelerators and thermonuclear fusion facilities

    E-Print Network [OSTI]

    Bilski, P; D'Errico, F; Esposito, A; Fehrenbacher, G; Fernàndez, F; Fuchs, A; Golnik, N; Lacoste, V; Leuschner, A; Sandri, S; Silari, M; Spurny, F; Wiegel, B; Wright, P

    2006-01-01

    This report outlines the research needs and research activities within Europe to develop new and improved methods and techniques for the characterization of complex radiation fields at workplaces around high-energy accelerators and the next generation of thermonuclear fusion facilities under the auspices of the COordinated Network for RAdiation Dosimetry (CONRAD) project funded by the European Commission.

  18. Driving and Charging Behavior of Nissan Leafs in The EV Project with Access to Workplace Charging

    SciTech Connect (OSTI)

    Don Scoffield; Shawn Salisbury; John Smart

    2014-11-01

    This paper documents findings from analysis of data collected from Nissan Leafs enrolled in The EV Project who parked and charged at workplaces with EV charging equipment. It will be published as a white paper on INL's website, accessible by the general public.

  19. Workplace Charging Behavior of Nissan Leafs in The EV Project at Six Work Sites

    SciTech Connect (OSTI)

    David Rohrbaugh; John Smart

    2014-11-01

    This paper documents findings from analysis of data collected from Nissan Leafs enrolled in The EV Project who parked and charged at six workplaces with EV charging equipment. It will be published as a white paper on INL's website, accessible by the general public.

  20. Health physics manual of good practices for the prompt detection of airborne plutonium in the workplace

    SciTech Connect (OSTI)

    Not Available

    1988-07-01

    This manual provides guidance to US Department of Energy (DOE) facilities on the prompt detection of airborne plutonium in the workplace. Information is first given to aid in detection systems that will function effectively in various workplaces. Steps in designing a system are covered: its general requirements, the plotting of workplace sources of plutonium, and methods of determining workplace airflow patterns. Guidance is provided on the proper numbers and locations of probe sites, the orientation of probes for representative sampling, and the mixture of stationary and portable probes. Recommendations for delivery in sampling systems include examination of particle loss and self-absorption problems, methods of eliminating air leakage in the system, and optimization of decontamination capabilities. System flow rate, requirements in a collection medium, burial loss and pressure drop, and prudent frequency of renewing the collection medium are among air sampling considerations covered. After a discussion of controlling airflow and of vacuum sources and system backups, the checkpoints to ensure system reliability are listed. The manual then discusses instrument specifications that provide correct airborne plutonium concentrations and reliably activate alarms. Focusing on the interrelationship of all components, essential factors in instrument reliability are addressed: the regulatory lower limit of detection and performance specifications of detectors and filters, maintenance and calibration requirements, and features of commonly used plutonium air-sampling instruments. Finally, the manual advises on establishing a documentation program to archive and evaluate the performance of a plutonium air-sampling program.

  1. "...powered bodies turn to commodities..." -stereolab Drugs and Drug Abuse

    E-Print Network [OSTI]

    Teissére, Jeremy Alden

    "...powered bodies turn to commodities..." - stereolab BIO 115 Fall, 2008 Drugs and Drug Abuse the current narratives surrounding drug use. In parallel, we will closely examine the putative mechanisms by which drugs act in the central nervous system ­ and also discuss how the action of these drugs has

  2. Drug delivery Sustained Drug Release from Non-eroding Nanoporous

    E-Print Network [OSTI]

    Sridhar, Srinivas

    Drug delivery Sustained Drug Release from Non-eroding Nanoporous Templates** Evin Gultepe, Dattatri drug, doxorubicin (Dox), from different non-eroding nanopor- ous coatings. Detailed studies of drug phosphate-buffered saline (PBS), which is commonly employed to simulate in vivo conditions for drug release

  3. Fixed drug eruption caused by the Japanese herbal drug kakkonto

    E-Print Network [OSTI]

    Furuichi, Megumi; Hara, Hiroshi; Asano, Yukie; Makino, Teruhiko; Shimizu, Tadamichi

    2010-01-01

    Topical provocation of fixed drug eruption. Br J Dermatol.neglected offender for fixed drug eruptions. Eur J Dermatoloral and non-oral herbal drugs may cause FDE. References 1.

  4. Drug Use and Drug Policy in a Prohibition Regime

    E-Print Network [OSTI]

    MacCoun, Robert; Martin, Karin D.

    2008-01-01

    Prisoners (prior to offense), Drug-related Emergency RoomVisits, 2007 DAWN All illicit drugs Marijuana Cocaine Crack2/4/2008 - 41 Other Sentence Drug Sentence Federal Prisoners

  5. Anticoagulation Drug Therapy: A Review

    E-Print Network [OSTI]

    Harter, Katherine; Levine, Michael; Henderson, Sean O.

    2015-01-01

    et al. Anticoagulation Drug Therapy: A Review 15. NishijimaRandomized antiplatelet drugs. In: Goodman & Gilman’s The2008;24:2757-65. Cardiovasc Drugs. 2006;6:265-85. 34. Nordt

  6. Adolescent drug abuse - Awareness & prevention

    E-Print Network [OSTI]

    Chakravarthy, Bharath; Shah, Shyam; Lotfipour, Shahram

    2013-01-01

    alcohol, tobacco and other drug use. Int Rev Psychiatry.therapy for adolescent drug abuse. J Clin Child Psychol.outcomes in an indicated drug prevention program for high-

  7. A. Drug-Free Workplace/Drug-Free Schools Policy Statement This is a statement of the standards of conduct and disciplinary sanctions to be

    E-Print Network [OSTI]

    Wu, Shin-Tson

    abuse or dependency disorders. The University's alcoholic beverages policy is stated below. B. Campus, the University has formulated the following policies governing the sale, service, possession, and consumption in the residence halls and other #12;on-campus housing, unless otherwise prohibited by the governing organization

  8. Preventing Asthma in Animal Handlers Exposure to animals or animal products in the workplace can cause asthma and allergies.

    E-Print Network [OSTI]

    in the workplace can cause asthma and allergies. Animal handlers should take steps to protect themselves fromPreventing Asthma in Animal Handlers WARNING! Exposure to animals or animal products

  9. Fact #857 January 26, 2015 Number of Partner Workplaces Offering Electric Vehicle Charging More Than Tripled Since 2011

    Broader source: Energy.gov [DOE]

    The U.S. Department of Energy’s Workplace Charging Challenge began in early 2013 and currently has about 150 businesses/universities/organizations that are partners in the Challenge. A survey of...

  10. NEW - DOE G 444.1 1, Guide on Preventing and Responding to All Forms of Violence in the Workplace

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    This guide is a broad overview of the basic tools for a site to develop its site specific procedures for responding to workplace violence. Supports implementation of DOE P 444.1.

  11. Spatial dimensions of workplaces and the effects on commuting: the dase of metropolitan Dallas-Fort Worth 

    E-Print Network [OSTI]

    Shin, Sangyoung

    2004-09-30

    -density suburban workplaces are associated with shorter vehicle travel times but more drive-alone trips. While major suburban centers attain some level of compact development in terms of local activity mix and regional accessibility, employees in these centers...

  12. Preface: Nonclassical Transport

    E-Print Network [OSTI]

    Bolshov, L.

    2010-01-01

    models of solute transport in highly heterogeneous geologicSemenov. 2008b. Nonclassical transport processes in geologicand L. Matveev. 2008. Transport regimes and concentration

  13. Intelligent Transport Systems

    E-Print Network [OSTI]

    Deakin, Elizabeth; Frick, Karen Trapenberg; Skabardonis, Alexander

    2009-01-01

    in Sustainable Urban Transport: City Interview Synthesis (of Leeds, Institute for Transport Studies, forthcoming.I NTELLIGENT TRANSPORT SYSTEMS LINKING TECHNOLOGY AND

  14. Sustainability and Transport

    E-Print Network [OSTI]

    Gilbert, Richard

    2006-01-01

    Gilbert is a Toronto-based transport and energy consultantof the forthcoming book Transport Revolutions: Making theand substantial transition to transport systems based on

  15. Sandia Energy - Transportation Safety

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Transportation Safety Home Stationary Power Nuclear Fuel Cycle Nuclear Energy Safety Technologies Risk and Safety Assessment Transportation Safety Transportation SafetyTara...

  16. Drug Information Chart Notes Drug ad (intrinsic bias)

    E-Print Network [OSTI]

    Fletcher, Robin

    Drug Information Chart Notes Drug ad (intrinsic bias) Trade name Different for each company Dosage Same or different? A drug in a different dosage can be used for a different therapy. Precautions Check for pregnancy A complete book on drugs in pregnancy and lactation in bibliography. (unbiased

  17. Crystal structure of a concentrative nucleoside transporter from Vibrio cholerae at 2.4;#8201;Å

    SciTech Connect (OSTI)

    Johnson, Zachary Lee; Cheong, Cheom-Gil; Lee, Seok-Yong (Duke)

    2012-07-11

    Nucleosides are required for DNA and RNA synthesis, and the nucleoside adenosine has a function in a variety of signalling processes. Transport of nucleosides across cell membranes provides the major source of nucleosides in many cell types and is also responsible for the termination of adenosine signalling. As a result of their hydrophilic nature, nucleosides require a specialized class of integral membrane proteins, known as nucleoside transporters (NTs), for specific transport across cell membranes. In addition to nucleosides, NTs are important determinants for the transport of nucleoside-derived drugs across cell membranes. A wide range of nucleoside-derived drugs, including anticancer drugs (such as Ara-C and gemcitabine) and antiviral drugs (such as zidovudine and ribavirin), have been shown to depend, at least in part, on NTs for transport across cell membranes. Concentrative nucleoside transporters, members of the solute carrier transporter superfamily SLC28, use an ion gradient in the active transport of both nucleosides and nucleoside-derived drugs against their chemical gradients. The structural basis for selective ion-coupled nucleoside transport by concentrative nucleoside transporters is unknown. Here we present the crystal structure of a concentrative nucleoside transporter from Vibrio cholerae in complex with uridine at 2.4 {angstrom}. Our functional data show that, like its human orthologues, the transporter uses a sodium-ion gradient for nucleoside transport. The structure reveals the overall architecture of this class of transporter, unravels the molecular determinants for nucleoside and sodium binding, and provides a framework for understanding the mechanism of nucleoside and nucleoside drug transport across cell membranes.

  18. SUSTAINABLE TRANSPORTATION ENERGY PATHWAYS

    E-Print Network [OSTI]

    California at Davis, University of

    SUSTAINABLE TRANSPORTATION ENERGY PATHWAYS A Research Summary for Decision Makers Edited by Joan Ogden and Lorraine Anderson #12;SUSTAINABLE TRANSPORTATION ENERGY PATHWAYS #12;SUSTAINABLE;6 SUSTAINABLE TRANSPORTATION ENERGY PATHWAYS ACKNOWLEDGEMENTS #12;1 SUSTAINABLE TRANSPORTATION ENERGY PATHWAYS

  19. DRUG DISCOVERY AT PURDUE 2013-14

    E-Print Network [OSTI]

    Pittendrigh, Barry

    DRUG DISCOVERY AT PURDUE 2013-14 #12;PURDUE UNIVERSITY DRUG DISCOVERY 2 #12;PURDUE UNIVERSITY DRUG DISCOVERY 3 #12;PURDUE UNIVERSITY DRUG DISCOVERY 4 TABLE OF CONTENTS INTRODUCTION ..................................................................................................p. 8 ALPHABETICAL LIST OF DRUG DISCOVERY RESEARCHERS

  20. Beam Transport

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room News PublicationsAudits & Inspections AuditsBarbara McClintockSecurityBeam Transport Beam

  1. Stochastic Transport

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effect Photovoltaics -7541C.3X-rays3 Prepared by:'!Transport in PPCD Discharges by

  2. Greening Transportation

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformation Current HABFESOpportunitiesNERSC GettingGraphene's 3DGreenGreenTransportation

  3. Ultrasound-Enhanced Drug Transport and Distribution in the Brain

    E-Print Network [OSTI]

    2010-01-01

    including water, mannitol, inulin, and dextran (70 kDa; ART-Da), mannitol (180 Da), inulin (5 kDa), and dextran (70 kDa;

  4. Ultrasound-Enhanced Drug Transport and Distribution in the Brain

    E-Print Network [OSTI]

    2010-01-01

    enhanced taxol delivery in brain tumor patients usingopening of the blood–brain barrier in rabbits. Radiology.and Distribution in the Brain Ying Liu, 1 Sumit Paliwal, 2

  5. Transporting particulate material

    DOE Patents [OSTI]

    Aldred, Derek Leslie (North Hollywood, CA); Rader, Jeffrey A. (North Hollywood, CA); Saunders, Timothy W. (North Hollywood, CA)

    2011-08-30

    A material transporting system comprises a material transporting apparatus (100) including a material transporting apparatus hopper structure (200, 202), which comprises at least one rotary transporting apparatus; a stationary hub structure (900) constraining and assisting the at least one rotary transporting apparatus; an outlet duct configuration (700) configured to permit material to exit therefrom and comprising at least one diverging portion (702, 702'); an outlet abutment configuration (800) configured to direct material to the outlet duct configuration; an outlet valve assembly from the material transporting system venting the material transporting system; and a moving wall configuration in the material transporting apparatus capable of assisting the material transporting apparatus in transporting material in the material transporting system. Material can be moved from the material transporting apparatus hopper structure to the outlet duct configuration through the at least one rotary transporting apparatus, the outlet abutment configuration, and the outlet valve assembly.

  6. Transportation Data Programs:Transportation Energy Data Book...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Transportation Data Programs:Transportation Energy Data Book,Vehicle Technologies Market Report, and VT Fact of the Week Transportation Data Programs:Transportation Energy Data...

  7. 1 Workplace Violence Prevention: CampusSpecific Training Supplement| The City University Of New York/OHRM THE CITY UNIVERSITY OF NEW YORK

    E-Print Network [OSTI]

    Sun, Yi

    York/OHRM THE CITY UNIVERSITY OF NEW YORK CITY COLLEGE OF NEW YORK WORKPLACE VIOLENCE PREVENTION: CampusSpecific Training Supplement| The City University Of New York/OHRM HIGH RISK LOCATIONS1 Workplace Violence Prevention: CampusSpecific Training Supplement| The City University Of New

  8. Technical assessment of compliance with workplace air sampling requirements at WRAP

    SciTech Connect (OSTI)

    HACKWORTH, M.F.

    1999-06-02

    The purpose of this Technical Assessment is to satisfy HSRCM-1, ''Hanford Site Radiological Control Manual'' Article 551.4 for a documented study of facility Workplace Air Monitoring (WAM) programs. HSRCM-1 is the primary guidance for radiological control at Waste Management Federal Services of Hanford, Inc. (WMH). The HSRCM-1 complies with Title 10. Part 835 of the Code of Federal Regulations (10CFR835). This document provides an evaluation of the compliance of the Waste Receiving and Processing facility (WRAP) WAM program to the criteria standards, requirements, and documents compliance with the requirements where appropriate. Where necessary, it also indicates changes needed to bring specific locations into compliance.

  9. Oral Drug Absorption

    E-Print Network [OSTI]

    Yamashita, Shinji

    2006-10-26

    Stability 0 20 40 60 80 100 25 10 5 1 0.5 size? r 0 (?m) Fr action absor b ed in hum an (% ) Peff =5.0 Peff =3.0 Peff =1.0 Peff =0.5 Peff =0.1 Solubility? Cs = 1.0 (?g/ml) Effect of micronization on intestinal absorption of poorly soluble drugs Peff... ?? permeability to human intestine? (cm/sec x 10 -4 ) 8 Effect of Solubility on intestinal absorption of poorly soluble drugs Cs (?g/ml) 0 5 10 15 50 Fr action absor b ed in hum an (% ) 0 20 40 60 80 100 Peff =5.0 Peff =3.0 Peff =1.0 Peff =0.5 Peff =0.1 r 0 = 1...

  10. Erosion and Optimal Transport

    E-Print Network [OSTI]

    Birnir, Bjorn; Rowlett, Julie

    2010-01-01

    383 pp. EROSION AND OPTIMAL TRANSPORT [23] I. Ekeland and T.and D. Simons, Sediment transport capacity of overland ?ow,measure spaces via optimal transport, Ann. of Math. (2),

  11. Transporting Hazardous Materials

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Transporting Hazardous Materials The procedures given below apply to all materials that are considered to be hazardous by the U.S. Department of Transportation (DOT). Consult your...

  12. Sustainability and Transport

    E-Print Network [OSTI]

    Gilbert, Richard

    2006-01-01

    2005. Integrating Sustainability into the Trans- portationTHOUGHT PIECE Sustainability and Transport by Richardof the concept of sustainability to transport planning. In

  13. Systems Theory for Pharmaceutical Drug Discovery

    E-Print Network [OSTI]

    Aswani, Anil Jayanti

    2010-01-01

    model to identify multiple drug targets which can be candidates for the traditional process of drug discovery.

  14. Computational study of the transport mechanisms of molecules and ions in solid materials 

    E-Print Network [OSTI]

    Zhang, Yingchun

    2009-06-02

    Transport of ions and molecules in solids is a very important process in many technological applications, for example, in drug delivery, separation processes, and in power sources such as ion diffusion in electrodes or in ...

  15. Drug Discovery Today Volume 11, Numbers 19/20 October 2006 REVIEWS Is the oral route possible for peptide and

    E-Print Network [OSTI]

    Peppas, Nicholas A.

    small hydro- philic molecules that can fit in these spaces [7]. In the case of one of the most widely. Unlike conventional small molecular drugs, clinical development of these types of drug to be actively transported across the epithelial lining of the small intestine in membrane-bound vesicles after

  16. Transport Equations Thomas Hillen

    E-Print Network [OSTI]

    Hillen, Thomas

    Transport Equations Thomas Hillen supported by NSERC University of Alberta, Edmonton Transport V , V compact and symmetric. Transport Equations ­ p.2/33 #12;Directed Movement The equation pt(t, x of v. Transport Equations ­ p.3/33 #12;With Directional Changes µ: turning rate. T(v, v ): probability

  17. Motor Transport Co. 

    E-Print Network [OSTI]

    Unknown

    2011-09-05

    METROPOLITAN TRANSPORTATION PLAN Prepared by: The Longview Metropolitan Planning Organization In cooperation with: o City of Longview o City of White Oak o Gregg County o Harrison County o Texas Department of Transportation o U.S. Department... of Transportation o Federal Highway Administration o Federal Transit Administration Adopted November 12, 2009 TRANSPORTATION 2035 TABLE OF CONTENTS INTRODUCTION...

  18. INFORMATION: The Alaska Department of Labor and Workforce Development encourages employers and employees to reduce workplace hazards voluntarily

    E-Print Network [OSTI]

    Hartman, Chris

    employees about the locations and nature of operations, which could result in exposure to toxic or hazardous encourages employers and employees to reduce workplace hazards voluntarily and to develop and improve safety on the identification and elimination of hazards that could cause death, injury, or illness to employees and supervisors

  19. DRAFT - DOE G 444.1-1, Guide on Preventing and Responding to All Forms of Violence in the Workplace

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    To ensure all sites have the tools to implement processes, we have created this guide. Each site is expected to develop its own site specific set of procedures/process to implement DOE Policy 444.1 Preventing and Responding to all forms of violence in the Workplace.

  20. Introduction Transport in disordered graphene

    E-Print Network [OSTI]

    Fominov, Yakov

    Introduction Transport in disordered graphene Summary Ballistic transport in disordered graphene P, Gornyi, Mirlin Ballistic transport in disordered graphene #12;Introduction Transport in disordered graphene Summary Outline 1 Introduction Model Experimental motivation Transport in clean graphene 2

  1. Our Workplace

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefieldSulfateSciTechtail.Theory ofDid you notHeatMaRIEdioxideUser Careers/ HumanOur MissionPrograms

  2. PHCL4003: Anti-infective drugs: Drugs that kill invaders -2015 Spring Course Co-Directors

    E-Print Network [OSTI]

    Marchant, Jonathan

    1 PHCL4003: Anti-infective drugs: Drugs that kill invaders - 2015 Spring Course Co to antimicrobial chemotherapy Jan. 26: 2. Principles of antibacterial drugs I: Drug targets and cytotoxicity Jan. 28: 3. Principles of antibacterial drugs II: Drug resistance Feb. 2: 4. Antibacterial drugs

  3. Drug metabolizing enzymes activities versus genetic variances for drug of clinical pharmacogenomic relevance

    E-Print Network [OSTI]

    Wu, Alan HB

    2011-01-01

    this article as: Wu: Drug metabolizing enzyme activitiesgenetic variances for drug of clinical pharmacogenomicPROTEOMICS Open Access Drug metabolizing enzyme activities

  4. Final Progress Report: Developing Ethical Practices for Genetics Testing in the Workplace

    SciTech Connect (OSTI)

    Laura Roberts, MD; Teddy Warner, PhD

    2008-05-14

    Our multidisciplinary research team for this project involved collaboration between the Department of Psychiatry and Behavioral Medicine at the Medical College of Wisconsin (MCW) and the Department of Family and Community Medicine at the University of New Mexico Health Sciences Center (UNM HSC). Our research team in Wisconsin was led by Laura Roberts, M.D., Principal Investigator, and included Scott Helberg, MLS (Project Coordinator), Kate Green Hammond, Ph.D. (Consultant), Krisy Edenharder (Research Coordinator), and Mark Talatzko (Research Assistant). Our New Mexico-based team was led by Teddy Warner, Ph.D., Co-Principal Investigator and UNM Site Principal Investigator, and included Suzanne Roybal (Project Assistant), Darlyn Mabon (Project Assistant), Kate Green Hammond, PhD (Senior Research Scientist on the UNM team from 2004 until January, 2007), and Paulette Christopher (Research Assistant). In addition, computer technical and web support for the web-based survey conducted on a secure server at the University of New Mexico was provided by Kevin Wiley and Kim Hagen of the Systems and Programming Team of the Health Sciences Center Library and Information Center. We stated 3 aims in the grant proposal: (1) To collect web survey reports of the ethical perspectives, concerns, preferences and decision-making related to genetic testing using surveys from employees at: (a) Los Alamos National Laboratory (LANL); (b) Sandia National Laboratories (SNL); and (c) the University of New Mexico Health Sciences Center (UNMHSC); (2) To perform an extensive literature search and the extant survey data to develop evidence-based policy recommendations for ethically sound genetic testing associated with research and occupational health activities in the workplace; and, (3) To host a conference at the Medical College of Wisconsin to provide employers, workers, health professionals, researchers, the public, and the media an opportunity to consider ethical issues involved in genetic testing in the context of the workplace.

  5. Secure Transportation Management

    SciTech Connect (OSTI)

    Gibbs, P. W.

    2014-10-15

    Secure Transport Management Course (STMC) course provides managers with information related to procedures and equipment used to successfully transport special nuclear material. This workshop outlines these procedures and reinforces the information presented with the aid of numerous practical examples. The course focuses on understanding the regulatory framework for secure transportation of special nuclear materials, identifying the insider and outsider threat(s) to secure transportation, organization of a secure transportation unit, management and supervision of secure transportation units, equipment and facilities required, training and qualification needed.

  6. Water Transport Within the STack: Water Transport Exploratory...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Within the STack: Water Transport Exploratory Studies Water Transport Within the STack: Water Transport Exploratory Studies Part of a 100 million fuel cell award announced by DOE...

  7. Microfabricated injectable drug delivery system

    DOE Patents [OSTI]

    Krulevitch, Peter A. (Pleasanton, CA); Wang, Amy W. (Oakland, CA)

    2002-01-01

    A microfabricated, fully integrated drug delivery system capable of secreting controlled dosages of multiple drugs over long periods of time (up to a year). The device includes a long and narrow shaped implant with a sharp leading edge for implantation under the skin of a human in a manner analogous to a sliver. The implant includes: 1) one or more micromachined, integrated, zero power, high and constant pressure generating osmotic engine; 2) low power addressable one-shot shape memory polymer (SMP) valves for switching on the osmotic engine, and for opening drug outlet ports; 3) microfabricated polymer pistons for isolating the pressure source from drug-filled microchannels; 4) multiple drug/multiple dosage capacity, and 5) anisotropically-etched, atomically-sharp silicon leading edge for penetrating the skin during implantation. The device includes an externally mounted controller for controlling on-board electronics which activates the SMP microvalves, etc. of the implant.

  8. Midwestern Radioactive Materials Transportation Committee Agenda...

    Office of Environmental Management (EM)

    Midwestern Radioactive Materials Transportation Committee Agenda Midwestern Radioactive Materials Transportation Committee Agenda Midwestern Radioactive Materials Transportation...

  9. A Study of the Advanced Systems at the CMU Intelligent Workplace with an Evaluation of Potential Applications to Texas A&M International University 

    E-Print Network [OSTI]

    Claridge, D. E.; Gong, X.; Verdict, M.; Clingenpeel, K.

    2008-01-01

    A detailed study has been conducted of the performance of several innovative aspects of the Intelligent Workplace (IW) at Carnegie Mellon University, a low energy consumption building that uses radiant heating, cooling and a desiccant ventilation...

  10. This guide provides browser recommendations and troubleshooting steps for the Preventing Workplace Harassment Learning Program. If you need additional assistance accessing the program or troubleshooting, please

    E-Print Network [OSTI]

    forgotten your Andrew ID, try locating in the Directory: 1. Go to https://directory.andrew.cmu.edu/ 2. Enter that you are a new employee and could not locate the Workplace Harassment learning program in your Assigned

  11. Packaging and Transportation Safety

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1995-09-27

    Establishes safety requirements for the proper packaging and transportation of Department of Energy (DOE) offsite shipments and onsite transfers of hazardous materials and for modal transport. Canceled by DOE 460.1A

  12. Packaging and Transportation Safety

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2010-05-14

    The order establishes safety requirements for the proper packaging and transportation of DOE, including NNSA, offsite shipments and onsite transfers of radioactive and other hazardous materials and for modal transportation. Supersedes DOE O 460.1B.

  13. Sustainability and Transport

    E-Print Network [OSTI]

    Gilbert, Richard

    2006-01-01

    also known there as sustainable mobility. This de?nition wasfor De?ning Sustainable Transport and Mobility. [cited 13Sustainable transporta- tion is de?ned as a means to satisfy current transport and mobility

  14. Transportation Management Workshop: Proceedings

    SciTech Connect (OSTI)

    Not Available

    1993-10-01

    This report is a compilation of discussions presented at the Transportation Management Workshop held in Gaithersburg, Maryland. Topics include waste packaging, personnel training, robotics, transportation routing, certification, containers, and waste classification.

  15. Linear Motor Powered Transportation

    E-Print Network [OSTI]

    Thornton, Richard D.

    This special issue on linear-motor powered transportation covers both supporting technologies and innovative transport systems in various parts of the World, as this technology moves from the lab to commercial operations. ...

  16. Transportation Conference Speakers - 4 

    E-Print Network [OSTI]

    Unknown

    2011-08-17

    Laboratory experiments were performed to study and improve longshore sediment transport rate predictions. Measured total longshore transport in the laboratory was approximately three times greater for plunging breakers than spilling breakers. Three...

  17. Transportation Energy Futures Study

    Office of Energy Efficiency and Renewable Energy (EERE)

    Transportation accounts for 71% of total U.S. petroleum consumption and 33% of total greenhouse gas emissions. The Transportation Energy Futures (TEF) study examines underexplored oil-savings and...

  18. Transportation Market Distortions

    E-Print Network [OSTI]

    Litman, Todd

    2006-01-01

    roads and parking facilities is exempt from rent and taxes,road transport relative to rail (which pays rent and taxesroad tolls, parking fees, and Litman, Transportation Market Distortions higher fuel taxes

  19. Introduction to Transportation Planning

    E-Print Network [OSTI]

    Tipple, Brett

    Introduction to Transportation Planning CMP 4710/6710 Fall 2012 3 Credit Hours Room: ARCH 229 of City & Metropolitan Planning; Associate Dean, College of Architecture + Planning; former associate, social equity, fiscal health, and public health. Unfortunately, most transportation planning processes

  20. Transportation Conference Speakers - 1 

    E-Print Network [OSTI]

    Unknown

    2011-08-17

    Thiamin transport in Escherichia coli is a model system to establish the tolerance of derivatives for transport into the cell. Since little is known about what types of thiamin derivatives may be successfully taken into the cell through...

  1. Packaging and Transportation Safety

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1995-09-27

    Establishes safety requirements for the proper packaging and transportation of offsite shipments and onsite transfers of hazardous materials andor modal transport. Cancels DOE 1540.2 and DOE 5480.3

  2. Packaging and Transportation Safety

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1996-10-02

    Establishes safety requirements for the proper packaging and transportation of Department of Energy (DOE) offsite shipments and onsite transfers of hazardous materials and for modal transport. Cancels DOE O 460.1.

  3. Biofuels and Transportation

    E-Print Network [OSTI]

    Minnesota, University of

    Biofuels and Transportation Impacts and Uncertainties Some Observations of a Reformed Ethanol and Logistics Symposium 3 Topics · Why Biofuels · Ethanol Economics · Ethanol Transportation Equipment Biofuels? · National Security · Reduce Imports of oil · Peak Oil · Replace Fossil Resources

  4. Indianapolis Public Transportation Corporation

    SciTech Connect (OSTI)

    Not Available

    2004-12-01

    Fact sheet describes the National Renewable Energy Laboratory's evaluation of Indianapolis Public Transportation Corporation's (IndyGo's) hybrid electric buses.

  5. Parking & Transportation Services Sustainability &

    E-Print Network [OSTI]

    Minnesota, University of

    : 2011 #12;As a long-time leader in the areas of waste abatement, pollution reduction, energy management Metro Commuter Services Infinity Award ­ in recognition of alternative transportation programs. · 1996 to maintaining impressive and viable alternative transportation programs. TRANSPORTATION SYSTEM DESIGNS

  6. Analysis of Assembly Bill 310: Prescription Drugs

    E-Print Network [OSTI]

    California Health Benefits Review Program (CHBRP)

    2011-01-01

    pdf. Accessed February 2011. Medco. 2010 Drug Trend Report.www.drugtrend.com/art/drug_trend/pdf/DT_Report_2010.pdf.chronic myeloid leukaemia. Drugs. 2007;67(2): p. 299- April

  7. Prescription Drug List effective January 1, 2015

    E-Print Network [OSTI]

    Arnold, Jonathan

    1 Your 2015 Prescription Drug List effective January 1, 2015 Student Resources Traditional ThreeZIPcode. ·Lookuppossiblelower-costmedicationalternatives. ·Comparemedicationpricingandoptions. #12;2 Your Prescription Drug List This Prescription Drug List (PDL) outlines the most commonly prescribed medications for certain

  8. Effect of Drug Loading and Laser Surface Melting on Drug Release Profile from Biodegradable Polymer

    E-Print Network [OSTI]

    Yao, Y. Lawrence

    Effect of Drug Loading and Laser Surface Melting on Drug Release Profile from Biodegradable Polymer(L-lactic acid) is promising in drug delivery applications because it allows for drug release in a controlled manner. In a polymer-based drug delivery system, drug release is controlled by polymer degradation

  9. Effect of Drug Loading and Laser Surface Melting on Drug Release Profile from Biodegradable Polymer

    E-Print Network [OSTI]

    Yao, Y. Lawrence

    1 Effect of Drug Loading and Laser Surface Melting on Drug Release Profile from Biodegradable The biodegradable polymer such as poly(L-lactic acid) is promising in drug delivery applications because it allows for drug release in a controlled manner. In a polymer-based drug delivery system, drug release

  10. Drug-Drug Interaction Detection: A New Approach Based on Maximal Frequent Sequences

    E-Print Network [OSTI]

    Rosso, Paolo

    Drug-Drug Interaction Detection: A New Approach Based on Maximal Frequent Sequences Detecci´on de´armacos, extracci´on de relaciones, secuencias frecuentes maximales Abstract: In this paper, a new approach for Drug-Drug that contain Drug-Drug Interactions. Maximal Frequent Sequences define word sequences that are frequent

  11. EBS Radionuclide Transport Abstraction

    SciTech Connect (OSTI)

    J. Prouty

    2006-07-14

    The purpose of this report is to develop and analyze the engineered barrier system (EBS) radionuclide transport abstraction model, consistent with Level I and Level II model validation, as identified in Technical Work Plan for: Near-Field Environment and Transport: Engineered Barrier System: Radionuclide Transport Abstraction Model Report Integration (BSC 2005 [DIRS 173617]). The EBS radionuclide transport abstraction (or EBS RT Abstraction) is the conceptual model used in the total system performance assessment (TSPA) to determine the rate of radionuclide releases from the EBS to the unsaturated zone (UZ). The EBS RT Abstraction conceptual model consists of two main components: a flow model and a transport model. Both models are developed mathematically from first principles in order to show explicitly what assumptions, simplifications, and approximations are incorporated into the models used in the TSPA. The flow model defines the pathways for water flow in the EBS and specifies how the flow rate is computed in each pathway. Input to this model includes the seepage flux into a drift. The seepage flux is potentially split by the drip shield, with some (or all) of the flux being diverted by the drip shield and some passing through breaches in the drip shield that might result from corrosion or seismic damage. The flux through drip shield breaches is potentially split by the waste package, with some (or all) of the flux being diverted by the waste package and some passing through waste package breaches that might result from corrosion or seismic damage. Neither the drip shield nor the waste package survives an igneous intrusion, so the flux splitting submodel is not used in the igneous scenario class. The flow model is validated in an independent model validation technical review. The drip shield and waste package flux splitting algorithms are developed and validated using experimental data. The transport model considers advective transport and diffusive transport from a breached waste package. Advective transport occurs when radionuclides that are dissolved or sorbed onto colloids (or both) are carried from the waste package by the portion of the seepage flux that passes through waste package breaches. Diffusive transport occurs as a result of a gradient in radionuclide concentration and may take place while advective transport is also occurring, as well as when no advective transport is occurring. Diffusive transport is addressed in detail because it is the sole means of transport when there is no flow through a waste package, which may dominate during the regulatory compliance period in the nominal and seismic scenarios. The advective transport rate, when it occurs, is generally greater than the diffusive transport rate. Colloid-facilitated advective and diffusive transport is also modeled and is presented in detail in Appendix B of this report.

  12. Advanced Building Efficiency Testbed Initiative/Intelligent Workplace Energy Supply System; ABETI/IWESS

    SciTech Connect (OSTI)

    David Archer; Frederik Betz; Yun Gu; Rong Li; Flore Marion; Sophie Masson; Ming Qu; Viraj Srivastava; Hongxi Yin; Chaoqin Zhai; Rui Zhang; Elisabeth Aslanian; Berangere Lartigue

    2008-05-31

    ABETI/IWESS is a project carried out by Carnegie Mellon's Center for Building Performance and Diagnostics, the CBPD, supported by the U.S. Department of Energy/EERE, to design, procure, install, operate, and evaluate an energy supply system, an ESS, that will provide power, cooling, heating and ventilation for CBPD's Intelligent Workplace, the IW. The energy sources for this system, the IWESS, are solar radiation and bioDiesel fuel. The components of this overall system are: (1) a solar driven cooling and heating system for the IW comprising solar receivers, an absorption chiller, heat recovery exchanger, and circulation pump; (2) a bioDiesel fueled engine generator with heat recovery exchangers, one on the exhaust to provide steam and the other on the engine coolant to provide heated water; (3) a ventilation system including an enthalpy recovery wheel, an air based heat pump, an active desiccant wheel, and an air circulation fan; and (4) various convective and radiant cooling/heating units and ventilation air diffusers distributed throughout the IW. The goal of the ABETI/IWESS project is to demonstrate an energy supply system for a building space that will provide a healthy, comfortable environment for the occupants and that will reduce the quantity of energy consumed in the operation of a building space by a factor of 2 less than that of a conventional energy supply for power, cooling, heating, and ventilation based on utility power and natural gas fuel for heating.

  13. Regional Transportation Coordination Study 

    E-Print Network [OSTI]

    Golden Crescent Regional Planning Commission

    2006-01-01

    stream_source_info Golden Crescent Regional Transportation Coordination Study.pdf.txt stream_content_type text/plain stream_size 357268 Content-Encoding ISO-8859-1 stream_name Golden Crescent Regional Transportation Coordination... Study.pdf.txt Content-Type text/plain; charset=ISO-8859-1 Golden Crescent Regional Transit i Regional Transportation Coordination Study: 7-County Golden Crescent Region Regional...

  14. FUEL CELLS FOR TRANSPORTATION

    E-Print Network [OSTI]

    for Fuel Cells for Transportation Energy Efficiency and Renewable Energy Office of Transportation............................................................................................. 101 A. R&D of a 50-kW, High-Efficiency, High-Power-Density, CO-Tolerant PEM Fuel Cell Stack SystemFUEL CELLS FOR TRANSPORTATION 2 0 0 1 A N N U A L P R O G R E S S R E P O R T U.S. Department

  15. Discovering the Targets of Drugs Via Computational

    E-Print Network [OSTI]

    Discovering the Targets of Drugs Via Computational Systems Biology* Published, JBC Papers in Press is empowering the study of drug action. Studies on biological effects of chemical com- pounds have increased of drugs, with the collective potential to change the nature of drug discovery and pharmacological therapy

  16. Drug-Target Interaction Predicates Combining Similarities

    E-Print Network [OSTI]

    Daume III, Hal

    Drug-Target Interaction Predicates DataSet Combining Similarities Collective Inference Collective Inference and Multi-Relational Learning for Drug­Target Interaction Prediction Shobeir Fakhraei1, Bert Huang1 and Lise Getoor1,2 Poly-pharmacology Drug Repurposing Drug-Target Interaction Network Studies

  17. ELECTROCHEMICAL POWER FOR TRANSPORTATION

    E-Print Network [OSTI]

    Cairns, Elton J.

    2012-01-01

    of the Fuel Cell in Transportation Applications Workshop,practical fuel cell for commercial or consumer applicationfuel cell system engineer- ing is made, vehicle applications

  18. National Transportation Stakeholders Forum

    Office of Environmental Management (EM)

    Nuclear Fuel Grand BC and High-Level Radioactive Waste - Jeff Williams, Director, Nuclear Fuel Storage and Transportation Planning Project, DOEOffice of Nuclear Energy National...

  19. Radioactive Material Transportation Practices

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2002-09-23

    Establishes standard transportation practices for Departmental programs to use in planning and executing offsite shipments of radioactive materials including radioactive waste. Does not cancel other directives.

  20. Transportation Energy Futures Snapshot

    Office of Energy Efficiency and Renewable Energy (EERE)

    This snapshot is a summary of the EERE reports that provide a detailed analysis of opportunities and challenges along the path to a more sustainable transportation energy future.

  1. Transportation and its Infrastructure

    E-Print Network [OSTI]

    2007-01-01

    gas vehicles Annual road tax differentiated by vintageand charges for road transport Tax/pricing measure Optimalannual circulation taxes, tolls and road charges and parking

  2. Transportation Energy Futures

    E-Print Network [OSTI]

    Sperling, Daniel

    1989-01-01

    TRANSPORTATION ment of Oil Shale Technology. Washing- ton,interest and investments in oil shale, ethanol, coal liquidsbiomass materials, coal, oil shale, tar sands, natural gas,

  3. UZ Colloid Transport Model

    SciTech Connect (OSTI)

    M. McGraw

    2000-04-13

    The UZ Colloid Transport model development plan states that the objective of this Analysis/Model Report (AMR) is to document the development of a model for simulating unsaturated colloid transport. This objective includes the following: (1) use of a process level model to evaluate the potential mechanisms for colloid transport at Yucca Mountain; (2) Provide ranges of parameters for significant colloid transport processes to Performance Assessment (PA) for the unsaturated zone (UZ); (3) Provide a basis for development of an abstracted model for use in PA calculations.

  4. Transportation and its Infrastructure

    E-Print Network [OSTI]

    2007-01-01

    of reduction options/ AERO. Ministry of Transport, Publicfrom aviation with the AERO modeling system Part I.from aviation with the AERO modeling system. Montreal,

  5. Natural Gas Transportation Resiliency

    Broader source: Energy.gov (indexed) [DOE]

    Transportation Resiliency Anders Johnson Director Pipeline System Design April 29, 2014 Confidential and Illustrative for discussion purposes only. The views expressed in this...

  6. Transportation Energy Futures Snapshot

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    modes, manage the demand for transportation, and shift the fuel mix to more sustainable sources necessary to reach these significant outcomes. Coordinating a...

  7. WASTE PACKAGE TRANSPORTER DESIGN

    SciTech Connect (OSTI)

    D.C. Weddle; R. Novotny; J. Cron

    1998-09-23

    The purpose of this Design Analysis is to develop preliminary design of the waste package transporter used for waste package (WP) transport and related functions in the subsurface repository. This analysis refines the conceptual design that was started in Phase I of the Viability Assessment. This analysis supports the development of a reliable emplacement concept and a retrieval concept for license application design. The scope of this analysis includes the following activities: (1) Assess features of the transporter design and evaluate alternative design solutions for mechanical components. (2) Develop mechanical equipment details for the transporter. (3) Prepare a preliminary structural evaluation for the transporter. (4) Identify and recommend the equipment design for waste package transport and related functions. (5) Investigate transport equipment interface tolerances. This analysis supports the development of the waste package transporter for the transport, emplacement, and retrieval of packaged radioactive waste forms in the subsurface repository. Once the waste containers are closed and accepted, the packaged radioactive waste forms are termed waste packages (WP). This terminology was finalized as this analysis neared completion; therefore, the term disposal container is used in several references (i.e., the System Description Document (SDD)) (Ref. 5.6). In this analysis and the applicable reference documents, the term ''disposal container'' is synonymous with ''waste package''.

  8. Sustainable Transportation (Fact Sheet)

    SciTech Connect (OSTI)

    Not Available

    2012-09-01

    This document highlights DOE's Office of Energy Efficiency and Renewable Energy's advancements in transportation technologies, alternative fuels, and fuel cell technologies.

  9. CALIFORNIA CENTER FOR INNOVATIVE TRANSPORTATION INSTITUTE OF TRANSPORTATION STUDIES

    E-Print Network [OSTI]

    CALIFORNIA CENTER FOR INNOVATIVE TRANSPORTATION INSTITUTE OF TRANSPORTATION STUDIES UNIVERSITY Investigator CCIT Research Report UCB-ITS-CWP-2011-2 The California Center for Innovative Transportation works;CALIFORNIA CENTER FOR INNOVATIVE TRANSPORTATION INSTITUTE OF TRANSPORTATION STUDIES UNIVERSITY OF CALIFORNIA

  10. Drug-Target Interaction Prediction for Drug Repurposing with Probabilistic Similarity Logic

    E-Print Network [OSTI]

    Daume III, Hal

    Drug-Target Interaction Prediction for Drug Repurposing with Probabilistic Similarity Logic Shobeir, USA getoor@cs.umd.edu ABSTRACT The high development cost and low success rate of drug dis- covery from appro- ved drugs. Computational methods can be effective in focu- sing efforts for such drug repurposing

  11. An approach to drug delivery using novel carbohydrates to carry drugs

    E-Print Network [OSTI]

    Davis, Ben G.

    An approach to drug delivery using novel carbohydrates to carry drugs has recently been described of the cancer drug doxorubicin targeted to hepatocytes in a mouse liver tumour model. Known as the LEAPT step involves administering the rhamnose-capped pro-drug; the drug is activated in the target cell once

  12. Drug-Initiated, Controlled Ring-Opening Polymerization for the Synthesis of Polymer-Drug Conjugates

    E-Print Network [OSTI]

    Cheng, Jianjun

    Drug-Initiated, Controlled Ring-Opening Polymerization for the Synthesis of Polymer-Drug Conjugates to paclitaxel and the subsequent ring-opening polymerization of lactide. The drug-initiated, controlled(-caprolactone)) was also achieved through drug/(BDI-II)ZnN(TMS)2-mediated controlled polymerization. These drug

  13. Drug-Initiated Ring-Opening Polymerization of OCarboxyanhydrides for the Preparation of Anticancer Drug-

    E-Print Network [OSTI]

    Cheng, Jianjun

    Drug-Initiated Ring-Opening Polymerization of OCarboxyanhydrides for the Preparation of Anticancer Drug- Poly(Ocarboxyanhydride) Nanoconjugates Qian Yin, Rong Tong,, Yunxiang Xu, Kwanghyun Baek of polymer-drug conjugates for nanoparticulate drug delivery: hydroxyl-containing drug (e.g., camptothecin

  14. Energy Department Welcomes Department of Transportation as New...

    Office of Environmental Management (EM)

    that are as affordable for the average American family by 2022 as a 2012 baseline gasoline-powered vehicle. By joining the Workplace Charging Challenge, the Department of...

  15. Transportation Todd Litman

    E-Print Network [OSTI]

    consumer cost savings. #12;11 Per Capita Transport EnergyPer Capita Transport Energy 0 0.5 1 1.5 2 2.5 D Problem? · Traffic congestion? · Road construction costs? · Parking congestion or costs? · Excessive costs to consumers? · Government costs? · Traffic crashes? · Lack of mobility for non-drivers? · Poor freight

  16. Expert systems in transportation

    SciTech Connect (OSTI)

    O'Leary, K.P.

    1988-01-01

    The 5 papers in the report deal with the following areas: Knowledge representation and software selection for expert-systems design; Expert-system architecture for retaining-wall design; Development of expert-systems technology in the California Department of Transportation; Development of an expert system to assist in the interactive graphic transit system design process; Expert systems development for contingency transportation planing.

  17. Packaging and Transportation Safety

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2003-04-04

    To establish safety requirements for the proper packaging and transportation of Department of Energy (DOE)/National Nuclear Security Administration (NNSA) offsite shipments and onsite transfers of hazardous materials and for modal transport. Cancels DOE O 460.1A. Canceled by DOE O 460.1C.

  18. Transport Layer Cornell University

    E-Print Network [OSTI]

    Low, Steven H.

    Transport Layer Ao Tang Cornell University Ithaca, NY 14853 Lachlan L. H. Andrew California. Low California Institute of Technology Pasadena, CA 91125 I. INTRODUCTION The Internet has evolved of the physical layer, the link layer, the network layer, the transport layer and the application layer1 . See

  19. TRANSPORTATION ENERGY RESEARCH PIER Transportation Research

    E-Print Network [OSTI]

    . The project also tested a Caterpillar C15 engine certified to 2007 U.S. Environmental Protection Agency.energy.ca.gov/research/ transportation/ January 2011 Heavy-Duty Vehicle Emissions and Fuel Consumption Improvement Illustration of a heavy-duty tractor-trailer modified to meet the SmartWayTM Equipment Standards for lower fuel

  20. STRUCTURAL REQUIREMENTS OF ORGANIC ANION TRANSPORTING POLYPEPTIDE MEDIATED TRANSPORT

    E-Print Network [OSTI]

    Weaver, Yi Miao

    2010-04-12

    The organic anion transporting polypeptides (human: OATP; other: Oatp) form a mammalian transporter superfamily that mediates the transport of structurally unrelated compounds across the cell membrane. Members in this superfamily participate...

  1. Essays on Urban Transportation and Transportation Energy Policy

    E-Print Network [OSTI]

    Kim, Chun Kon

    2008-01-01

    and Transportation Energy Policy Chun Kon Kim University of California,California Goyang, KOREA viii P???????????? ??? W?????? P????? The Impacts of Transportation EnergyCalifornia Transportation Center (UCTC) Regents’ Dissertation Fellowship University of California, Irvine California Energy

  2. Enhanced drug delivery capabilities from stents coated with absorbable polymer and crystalline drug

    E-Print Network [OSTI]

    Carlyle, Wenda C.

    Current drug eluting stent (DES) technology is not optimized with regard to the pharmacokinetics of drug delivery. A novel, absorbable-coating sirolimus-eluting stent (AC-SES) was evaluated for its capacity to deliver drug ...

  3. Drug Trafficking Organizations and Counter-Drug Strategies in the U.S.-Mexican Context

    E-Print Network [OSTI]

    Astorga, Luis; Shirk, David A.

    2010-01-01

    Analytic Assessment of U.S. Drug Policy. Washington, D.C. ,K. (2008). Mexico Faces New Drug Challenge: Mini-Submarines.Mayors on Front Line of the Drug War. Los Angeles Times Los

  4. Implementing Advances in Transport Security Technologies | Department...

    Office of Environmental Management (EM)

    Implementing Advances in Transport Security Technologies Implementing Advances in Transport Security Technologies Implementing Advances in Transport Security Technologies More...

  5. Transportation Storage Interface | Department of Energy

    Office of Environmental Management (EM)

    Storage Interface Transportation Storage Interface Regulation of Future Extended Storage and Transportation. Transportation Storage Interface More Documents & Publications Gap...

  6. Automated Transportation Logistics and Analysis System (ATLAS...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Packaging and Transportation Automated Transportation Logistics and Analysis System (ATLAS) Automated Transportation Logistics and Analysis System (ATLAS) The Department of...

  7. Transport Services (TAPS) BOF plan

    E-Print Network [OSTI]

    Welzl, Michael

    Transport Services (TAPS) BOF plan T. Moncaster, M. Welzl, D. Ros: dra5-moncaster-tsvwg-transport-services-00 h Reducing Internet Transport Latency Michael Welzl, with help from (alphabe/cal): Anna

  8. Brain science, addiction and drugs

    E-Print Network [OSTI]

    Wiesner, Karoline

    Designing your future Page 7 Theme: Nanoscience and Quantum Information Exchanging keys in the Canaries Page:searchUniversity of Bristol · Research Review · Issue 10 · October 2005 research themes issue #12;Research themes 2005 Establishedresearchthemes Theme: Neuroscience Brain science, addiction and drugs Other established research themes

  9. Improving Efficiency and Equity in Transportation Finance

    E-Print Network [OSTI]

    Watts, Michael

    2006-01-01

    Fueling Transportation Finance. ” Ian W. H. Parry andFueling Transportation Finance. ” Transportation ResearchFueling Transportation Finance: A Primer on the Gas Tax •

  10. Superconnections and Parallel Transport

    E-Print Network [OSTI]

    Dumitrescu, Florin

    2007-01-01

    This note addresses the construction of a notion of parallel transport along superpaths arising from the concept of a superconnection on a vector bundle over a manifold $M$. A superpath in $M$ is, loosely speaking, a path in $M$ together with an odd vector field in $M$ along the path. We also develop a notion of parallel transport associated with a connection (a.k.a. covariant derivative) on a vector bundle over a \\emph{supermanifold} which is a direct generalization of the classical notion of parallel transport for connections over manifolds.

  11. EBS Radionuclide Transport Abstraction

    SciTech Connect (OSTI)

    J.D. Schreiber

    2005-08-25

    The purpose of this report is to develop and analyze the engineered barrier system (EBS) radionuclide transport abstraction model, consistent with Level I and Level II model validation, as identified in ''Technical Work Plan for: Near-Field Environment and Transport: Engineered Barrier System: Radionuclide Transport Abstraction Model Report Integration'' (BSC 2005 [DIRS 173617]). The EBS radionuclide transport abstraction (or EBS RT Abstraction) is the conceptual model used in the total system performance assessment for the license application (TSPA-LA) to determine the rate of radionuclide releases from the EBS to the unsaturated zone (UZ). The EBS RT Abstraction conceptual model consists of two main components: a flow model and a transport model. Both models are developed mathematically from first principles in order to show explicitly what assumptions, simplifications, and approximations are incorporated into the models used in the TSPA-LA. The flow model defines the pathways for water flow in the EBS and specifies how the flow rate is computed in each pathway. Input to this model includes the seepage flux into a drift. The seepage flux is potentially split by the drip shield, with some (or all) of the flux being diverted by the drip shield and some passing through breaches in the drip shield that might result from corrosion or seismic damage. The flux through drip shield breaches is potentially split by the waste package, with some (or all) of the flux being diverted by the waste package and some passing through waste package breaches that might result from corrosion or seismic damage. Neither the drip shield nor the waste package survives an igneous intrusion, so the flux splitting submodel is not used in the igneous scenario class. The flow model is validated in an independent model validation technical review. The drip shield and waste package flux splitting algorithms are developed and validated using experimental data. The transport model considers advective transport and diffusive transport from a breached waste package. Advective transport occurs when radionuclides that are dissolved or sorbed onto colloids (or both) are carried from the waste package by the portion of the seepage flux that passes through waste package breaches. Diffusive transport occurs as a result of a gradient in radionuclide concentration and may take place while advective transport is also occurring, as well as when no advective transport is occurring. Diffusive transport is addressed in detail because it is the sole means of transport when there is no flow through a waste package, which may dominate during the regulatory compliance period in the nominal and seismic scenarios. The advective transport rate, when it occurs, is generally greater than the diffusive transport rate. Colloid-facilitated advective and diffusive transport is also modeled and is presented in detail in Appendix B of this report.

  12. Transportation and Greenhouse Gas Mitigation

    E-Print Network [OSTI]

    Lutsey, Nicholas P.; Sperling, Dan

    2008-01-01

    natural gas and liquefied petroleum gas have continued to make small contributions to transportation,transportation actions include electric power sector actions, eg coal to natural gas

  13. Office of Secure Transportation Activities

    Office of Environmental Management (EM)

    6th, 2012 WIPP Knoxville, TN OFFICE OF SECURE TRANSPORTATION Agency Integration Briefing Our Mission To provide safe and secure ground and air transportation of nuclear weapons,...

  14. Spent Fuel Transportation Risk Assessment

    Office of Environmental Management (EM)

    Spent Fuel Transportation Risk Assessment (SFTRA) Draft NUREG-2125 Overview for National Transportation Stakeholders Forum John Cook Division of Spent Fuel Storage and...

  15. Transportation and its Infrastructure

    E-Print Network [OSTI]

    2007-01-01

    IEA personnel (WBCSD, 2004b), the WEO 2004 and Mobility 2030are quite similar. The WEO 2006 (IEA, 2006b) includes higherwhile the IEA’s more recent WEO 2006 projects transport

  16. Optimization of Maritime Transportation

    E-Print Network [OSTI]

    Grossmann, Ignacio E.

    and Technology Management Norwegian University of Science and Technology, Trondheim, Norway Enterprise and D. Ronen (2007). Maritime transportation. Handbooks in Operations Research and Management Science (consolidation in the manufacturing sector, increasing competition, profit margins reduced, mergers and pooling

  17. Accident resistant transport container

    DOE Patents [OSTI]

    Andersen, John A. (Albuquerque, NM); Cole, James K. (Albuquerque, NM)

    1980-01-01

    The invention relates to a container for the safe air transport of plutonium having several intermediate wood layers and a load spreader intermediate an inner container and an outer shell for mitigation of shock during a hypothetical accident.

  18. Transportation Baseline Report

    SciTech Connect (OSTI)

    Fawcett, Ricky Lee; Kramer, George Leroy Jr.

    1999-12-01

    The National Transportation Program 1999 Transportation Baseline Report presents data that form a baseline to enable analysis and planning for future Department of Energy (DOE) Environmental Management (EM) waste and materials transportation. In addition, this Report provides a summary overview of DOE’s projected quantities of waste and materials for transportation. Data presented in this report were gathered as a part of the IPABS Spring 1999 update of the EM Corporate Database and are current as of July 30, 1999. These data were input and compiled using the Analysis and Visualization System (AVS) which is used to update all stream-level components of the EM Corporate Database, as well as TSD System and programmatic risk (disposition barrier) information. Project (PBS) and site-level IPABS data are being collected through the Interim Data Management System (IDMS). The data are presented in appendices to this report.

  19. Atmospheric Transport of Radionuclides

    SciTech Connect (OSTI)

    Crawford, T.V.

    2003-03-03

    The purpose of atmospheric transport and diffusion calculations is to provide estimates of concentration and surface deposition from routine and accidental releases of pollutants to the atmosphere. This paper discusses this topic.

  20. National Transportation Stakeholders Forum

    Office of Environmental Management (EM)

    next webinar is scheduled to occur in June 2013 TRIBAL NATIONS CAUCUS UPDATE WIKI AND NTSF WEB SITES ntsf.wikidot.com www.em.doe.govPagesNationalTransportationForum.aspx...

  1. Transport in granular systems

    E-Print Network [OSTI]

    Wendell, Dawn M. (Dawn Marie), 1983-

    2011-01-01

    There are many situations in which a continuum view of granular systems does not fully capture the relevant mechanics. In order for engineers to be able to design systems for transporting granular materials, there needs ...

  2. Transportation Storage Interface

    Office of Environmental Management (EM)

    in above- ground bunkers, each of which is about the size of a one-car garage. Spent Fuel Storage: Dual Purpose Cask Systems 8 Spent Fuel Storage and Transportation: Framework...

  3. PBA Transportation Websites

    Broader source: Energy.gov [DOE]

    PBA Transportation Websites presented to the DOE Systems Analysis Workshop held in Washington, D.C. July 28-29, 2004 to discuss and define role of systems analysis in DOE Hydrogen Program.

  4. Fluid transport container

    DOE Patents [OSTI]

    DeRoos, B.G.; Downing, J.P. Jr.; Neal, M.P.

    1995-11-14

    An improved fluid container for the transport, collection, and dispensing of a sample fluid that maintains the fluid integrity relative to the conditions of the location at which it is taken. More specifically, the invention is a fluid sample transport container that utilizes a fitting for both penetrating and sealing a storage container under controlled conditions. Additionally, the invention allows for the periodic withdrawal of portions of the sample fluid without contamination or intermixing from the environment surrounding the sample container. 13 figs.

  5. Transportation fuels from wood

    SciTech Connect (OSTI)

    Baker, E.G.; Elliott, D.C.; Stevens, D.J.

    1980-01-01

    The various methods of producing transportation fuels from wood are evaluated in this paper. These methods include direct liquefaction schemes such as hydrolysis/fermentation, pyrolysis, and thermochemical liquefaction. Indirect liquefaction techniques involve gasification followed by liquid fuels synthesis such as methanol synthesis or the Fischer-Tropsch synthesis. The cost of transportation fuels produced by the various methods are compared. In addition, three ongoing programs at Pacific Northwest Laboratory dealing with liquid fuels from wood are described.

  6. Packaging for a drug delivery microelectromechanical system

    E-Print Network [OSTI]

    Ho Duc, Hong Linh, 1978-

    2005-01-01

    Local drug delivery is a fast expanding field, and has been a center of attention for researchers in medicine in the last decade. Its advantages over systemic drug delivery are clear in cancer therapy, with localized tumors. ...

  7. Financing drug discovery for orphan diseases

    E-Print Network [OSTI]

    Fagnan, David Erik

    Recently proposed ‘megafund’ financing methods for funding translational medicine and drug development require billions of dollars in capital per megafund to de-risk the drug discovery process enough to issue long-term ...

  8. The pipeline and future of drug development in schizophrenia

    E-Print Network [OSTI]

    Gray, J A; Roth, B L

    2007-01-01

    The Pipeline and Future of Drug Development in SchizophreniaThe Drug Discovery Pipeline in Schizophrenia Keywords:discuss the current pipeline of drugs for schizophrenia,

  9. Membrane Transport Chloride Transport Across Vesicle and Cell

    E-Print Network [OSTI]

    Smith, Bradley D.

    Membrane Transport Chloride Transport Across Vesicle and Cell Membranes by Steroid-Based Receptors-established that molecules which transport cations across cell membranes (cationophores) can have potent biological effects of biological activity. Indeed, chloride transporters have direct medical potential as treatments for cystic

  10. Parking and Transport Policy Page 1 Parking and Transport Policy

    E-Print Network [OSTI]

    Mucina, Ladislav

    Parking and Transport Policy Page 1 Parking and Transport Policy Category: Facilities, Campus Life 1. PURPOSE To standardise and manage parking and transport on the Curtin Bentley campus including that support both State Government and University objectives in a manner that encourages public transport use

  11. CALIFORNIA CENTER FOR INNOVATIVE TRANSPORTATION INSTITUTE OF TRANSPORTATION STUDIES

    E-Print Network [OSTI]

    CALIFORNIA CENTER FOR INNOVATIVE TRANSPORTATION INSTITUTE OF TRANSPORTATION STUDIES UNIVERSITY-ITS-CWP-2010-4 This work was performed by the California Center for Innovative Transportation, a research group at the University of California, Berkeley, in cooperation with the State of California Business, Transportation

  12. CALIFORNIA CENTER FOR INNOVATIVE TRANSPORTATION INSTITUTE OF TRANSPORTATION STUDIES

    E-Print Network [OSTI]

    CALIFORNIA CENTER FOR INNOVATIVE TRANSPORTATION INSTITUTE OF TRANSPORTATION STUDIES UNIVERSITY-ITS-CWP-2011-6 ISSN 1557-2269 The California Center for Innovative Transportation works with researchers that improve the efficiency, safety, and security of the transportation system. #12;#12;CALIFORNIA CENTER

  13. Predicting new molecular targets for known drugs

    E-Print Network [OSTI]

    Kaski, Samuel

    ARTICLES Predicting new molecular targets for known drugs Michael J. Keiser1,2 *, Vincent Setola3 drugs are intended to be selective, at least some bind to several physiological targets, explaining side effects and efficacy. Because many drug­target combinations exist, it would be useful to explore possible

  14. CMVO Drug Testing Program Reasonable Suspicion Testing

    E-Print Network [OSTI]

    Sin, Peter

    CMVO Drug Testing Program Reasonable Suspicion Testing CMVO Revised Suspicion Form (Revised 6/08) Guidelines for Reasonable Suspicion Drug and Alcohol Testing: A supervisor, trained in accordance with 49 CFR involved in an incident that requires drug/alcohol testing as set forth in 382.307. Remember: Reasonable

  15. Focus Article Open challenges in magnetic drug

    E-Print Network [OSTI]

    Shapiro, Benjamin

    Focus Article Open challenges in magnetic drug targeting Benjamin Shapiro,1,2 Sandip Kulkarni,1 Aleksander Nacev,3 Silvia Muro,1,4 Pavel Y. Stepanov3 and Irving N. Weinberg3 The principle of magnetic drug is that highlight- ing these challenges will help researchers translate magnetic drug targeting from a novel concept

  16. Drugs and Behavior (Psychology 320 Sec. 001)

    E-Print Network [OSTI]

    Hopfinger, Joseph B.

    1 Drugs and Behavior (Psychology 320 Sec. 001) Syllabus Example Text: Maisto, Galizio and Conners. Drug Use and Abuse. Harcourt Brace College Publishers. 2008, Fifth Edition. Prerequisites: This course of drugs of abuse. An overview of basic pharmacology and behavioral pharmacology will be provided followed

  17. Proctors' Memorandum on Drugs Misuse Guidelines from Proctors' Office on Dealing with Drugs Misuse

    E-Print Network [OSTI]

    Henderson, Gideon

    Proctors' Memorandum on Drugs Misuse Guidelines from Proctors' Office on Dealing with Drugs Misuse The use of specified drugs is illegal within the UK, and is inimical to the University's primary objectives of the pursuit of academic study and research. The presence of drugs within the University

  18. Dimeric Drug Polymeric Nanoparticles with Exceptionally High Drug Loading and Quantitative Loading Efficiency

    E-Print Network [OSTI]

    Cheng, Jianjun

    Dimeric Drug Polymeric Nanoparticles with Exceptionally High Drug Loading and Quantitative LoadingChampaign, Urbana, Illinois 61801, United States Key Laboratory of Smart Drug Delivery, Ministry of Education-molecule drugs in hydrophobic polymers or amphiphilic copolymers has been extensively used for preparing

  19. Experimenting with Drugs (and Topic Models): Multi-Dimensional Exploration of Recreational Drug Discussions

    E-Print Network [OSTI]

    Dredze, Mark

    Experimenting with Drugs (and Topic Models): Multi-Dimensional Exploration of Recreational Drug of new recreational drugs and trends re- quires mining current information from non-traditional text components. The resulting model learns factors that correspond to drug type, delivery method (smoking

  20. Automatic Drug Side Effect Discovery from Online Patient-Submitted Reviews: Focus on Statin Drugs

    E-Print Network [OSTI]

    Automatic Drug Side Effect Discovery from Online Patient-Submitted Reviews: Focus on Statin Drugs become empowered to share personal experiences regarding prescription drugs via Web page discussion from patient-provided drug reviews on health-related web sites. We focus on the statin class

  1. HAZARDOUS DRUG SAFETY AND HEALTH PLAN FOR HANDLING ANTINEOPLASTIC OTHER HAZARDOUS DRUGS IN CLINICAL ENVIRONMENTS

    E-Print Network [OSTI]

    Kim, Duck O.

    HAZARDOUS DRUG SAFETY AND HEALTH PLAN FOR HANDLING ANTINEOPLASTIC AND OTHER HAZARDOUS DRUGS IN CLINICAL ENVIRONMENTS (5/3/2013) Introduction Drugs have a successful history of use in treating diseases and are responsible for many medical advances over the past century. However, virtually every drug has side effects

  2. NREL: Transportation Research - Transportation Deployment Support

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration wouldMass map shines lightGeospatial ToolkitSMARTSWorking WithSuccess StoriesTransportation

  3. NREL: Transportation Research - Transportation Secure Data Center

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration wouldMass map shines lightGeospatial ToolkitSMARTSWorking WithSuccessTransportation Secure Data

  4. NREL: Transportation Research - Transportation and Hydrogen Newsletter:

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration wouldMass map shines lightGeospatial ToolkitSMARTSWorking WithSuccessTransportation Secure

  5. NREL: Transportation Research - Transportation and Hydrogen Newsletter:

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration wouldMass map shines lightGeospatial ToolkitSMARTSWorking WithSuccessTransportation

  6. Thermal and Electrical Transport in Oxide Heterostructures

    E-Print Network [OSTI]

    Ravichandran, Jayakanth

    2011-01-01

    of thermal conductivity . . . . . . . . . . . . . . . .4.4 Thermal transport in2.3.2 Thermal transport . . . . . . . . . . . . . . . .

  7. Bullying in the Workplace Everyone knows about bullies in the school yard, but grown-up bullies can be just as big of a problem.

    E-Print Network [OSTI]

    Leistikow, Bruce N.

    , and their family members. Whether the problem is work-related, personal, career or relationship focused, ASAP can be just as big of a problem. Workplace bullies can cause serious troubles on the job. We have all had can affect a company's bottom line in a variety of ways. First and foremost, there are serious

  8. Drugs in Cinema: Separating the Myths from Reality

    E-Print Network [OSTI]

    Iannicelli, Paul

    2001-01-01

    Drugs in Cinema: Separating the Myths from Reality PaulSUMMARY 7 (2000). DRUGS IN CINEMA policy has a significantviolence in film. DRUGS IN CINEMA III. HISTORY OF DRUG USE

  9. Attoheat transport phenomena

    E-Print Network [OSTI]

    J. Marciak-Kozlowska; M. Pelc; M. A. Kozlowski

    2009-06-09

    Fascinating developments in optical pulse engineering over the last 20 years lead to the generation of laser pulses as short as few femtosecond, providing a unique tool for high resolution time domain spectroscopy. However, a number of the processes in nature evolve with characteristic times of the order of 1 fs or even shorter. Time domain studies of such processes require at first place sub-fs resolution, offered by pulse depicting attosecond localization. The generation, characterization and proof of principle applications of such pulses is the target of the attoscience. In the paper the thermal processes on the attosecond scale are described. The Klein-Gordon and Proca equations are developed. The relativistic effects in the heat transport on nanoscale are discussed. It is shown that the standard Fourier equation can not be valid for the transport phenomena induced by attosecond laser pulses. The heat transport in nanoparticles and nanotubules is investigated.

  10. Multi-modal Transportation > Highway Transportation > Trucking > Railroad transportation > Public transit > Rural transportation > Rural transit > Freight pipeline transportation > Airport planning and development > Airport maintenance > Bicycle and pedes

    E-Print Network [OSTI]

    and development > Airport maintenance > Bicycle and pedestrian > Ports and waterways >>> Transportation operat and development > Airport maintenance > Bicycle and pedestrian > Ports and waterways >>> Transportation operations pipeline transportation > Airport planning and development > Airport maintenance > Bicycle and pedestrian

  11. Vaginal mesh grafts and the Food and Drug Administration

    E-Print Network [OSTI]

    Ostergard, Donald R.

    2010-01-01

    and the Food and Drug Administration Donald R. Ostergardthe food and drug administration's (FDA) 510(k) process of

  12. Heavy-flavor transport

    E-Print Network [OSTI]

    Andrea Beraudo

    2015-10-29

    The formation of a hot deconfined medium (Quark-Gluon Plasma) in high-energy nuclear collisions affects heavy-flavor observables. In the low/moderate-pT range transport calculations allow one to simulate the propagation of heavy quarks in the plasma and to evaluate the effect of the medium on the final hadronic spectra: results obtained with transport coefficients arising from different theoretical approaches can be compared to experimental data. Finally, a discussion of possible effects on heavy-flavor observables due to the possible formation of a hot-medium in small systems (like in p-A collisions) is presented.

  13. Testing Drugs Versus Testing For Drug Use: Private Risk Management in the Shadow of the Criminal Law

    E-Print Network [OSTI]

    MacCoun, Robert J.

    2007-01-01

    Preface: The Varieties of Drug Control at the Dawn of thetbl.1.1. Id. See Peter Reuter, Drug Use Measures: What AreBetween Student Illicit Drug Use and School Drug-Testing

  14. Mass Transport within Soils

    SciTech Connect (OSTI)

    McKone, Thomas E.

    2009-03-01

    Contaminants in soil can impact human health and the environment through a complex web of interactions. Soils exist where the atmosphere, hydrosphere, geosphere, and biosphere converge. Soil is the thin outer zone of the earth's crust that supports rooted plants and is the product of climate and living organisms acting on rock. A true soil is a mixture of air, water, mineral, and organic components. The relative proportions of these components determine the value of the soil for agricultural and for other human uses. These proportions also determine, to a large extent, how a substance added to soil is transported and/or transformed within the soil (Spositio, 2004). In mass-balance models, soil compartments play a major role, functioning both as reservoirs and as the principal media for transport among air, vegetation, surface water, deeper soil, and ground water (Mackay, 2001). Quantifying the mass transport of chemicals within soil and between soil and atmosphere is important for understanding the role soil plays in controlling fate, transport, and exposure to multimedia pollutants. Soils are characteristically heterogeneous. A trench dug into soil typically reveals several horizontal layers having different colors and textures. As illustrated in Figure 1, these multiple layers are often divided into three major horizons: (1) the A horizon, which encompasses the root zone and contains a high concentration of organic matter; (2) the B horizon, which is unsaturated, lies below the roots of most plants, and contains a much lower organic carbon content; and (3) the C horizon, which is the unsaturated zone of weathered parent rock consisting of bedrock, alluvial material, glacial material, and/or soil of an earlier geological period. Below these three horizons lies the saturated zone - a zone that encompasses the area below ground surface in which all interconnected openings within the geologic media are completely filled with water. Similarly to the unsaturated zone with three major horizons, the saturated zone can be further divided into other zones based on hydraulic and geologic conditions. Wetland soils are a special and important class in which near-saturation conditions exist most of the time. When a contaminant is added to or formed in a soil column, there are several mechanisms by which it can be dispersed, transported out of the soil column to other parts of the environment, destroyed, or transformed into some other species. Thus, to evaluate or manage any contaminant introduced to the soil column, one must determine whether and how that substance will (1) remain or accumulate within the soil column, (2) be transported by dispersion or advection within the soil column, (3) be physically, chemically, or biologically transformed within the soil (i.e., by hydrolysis, oxidation, etc.), or (4) be transported out of the soil column to another part of the environment through a cross-media transfer (i.e., volatilization, runoff, ground water infiltration, etc.). These competing processes impact the fate of physical, chemical, or biological contaminants found in soils. In order to capture these mechanisms in mass transfer models, we must develop mass-transfer coefficients (MTCs) specific to soil layers. That is the goal of this chapter. The reader is referred to other chapters in this Handbook that address related transport processes, namely Chapter 13 on bioturbation, Chapter 15 on transport in near-surface geological formations, and Chapter 17 on soil resuspention. This chapter addresses the following issues: the nature of soil pollution, composition of soil, transport processes and transport parameters in soil, transformation processes in soil, mass-balance models, and MTCs in soils. We show that to address vertical heterogeneity in soils in is necessary to define a characteristic scaling depth and use this to establish process-based expressions for soil MTCs. The scaling depth in soil and the corresponding MTCs depend strongly on (1) the composition of the soil and physical state of the soil, (2) the chemical and physic

  15. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect (OSTI)

    Troy Reed; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Gerald Kane; Mark Pickell; Len Volk; Mike Volk; Barkim Demirdal; Affonso Lourenco; Evren Ozbayoglu; Paco Vieira

    2000-10-30

    This is the first quarterly progress report for Year 2 of the ACTS project. It includes a review of progress made in Flow Loop development and research during the period of time between July 14, 2000 and September 30, 2000. This report presents information on the following specific tasks: (a) Progress in Advanced Cuttings Transport Facility design and development (Task 2), (b) Progress on research project (Task 8): ''Study of Flow of Synthetic Drilling Fluids Under Elevated Pressure and Temperature Conditions'', (c) Progress on research project (Task 6): ''Study of Cuttings Transport with Foam Under LPAT Conditions (Joint Project with TUDRP)'', (d) Progress on research project (Task 7): ''Study of Cuttings Transport with Aerated Muds Under LPAT Conditions (Joint Project with TUDRP)'', (e) Progress on research project (Task 9): ''Study of Foam Flow Behavior Under EPET Conditions'', (f) Initiate research on project (Task 10): ''Study of Cuttings Transport with Aerated Mud Under Elevated Pressure and Temperature Conditions'', (g) Progress on instrumentation tasks to measure: Cuttings concentration and distribution (Tasks 11), and Foam properties (Task 12), (h) Initiate a comprehensive safety review of all flow-loop components and operational procedures. Since the previous Task 1 has been completed, we will now designate this new task as: (Task 1S). (i) Activities towards technology transfer and developing contacts with Petroleum and service company members, and increasing the number of JIP members.

  16. Spin Transport Shingo Katsumoto

    E-Print Network [OSTI]

    Iye, Yasuhiro

    -1-5 Kashiwanoha, Kashiwa, Chiba 277-8581, Japan According to DARPA's definition, "Spintronics"[1] means "Spin Transport Electronics". The issue "Spin Trans- port" thus covers all the fields of spintronics and one devices. In semiconductor spintronics devices, we therefore utilize the differences in n, , m for up

  17. EPAct Transportation Regulatory Activities

    SciTech Connect (OSTI)

    2011-11-21

    The U.S. Department of Energy's (DOE) Vehicle Technologies Program manages several transportation regulatory activities established by the Energy Policy Act of 1992 (EPAct), as amended by the Energy Conservation Reauthorization Act of 1998, EPAct 2005, and the Energy Independence and Security Act of 2007 (EISA).

  18. Artificial oxygen transport protein

    DOE Patents [OSTI]

    Dutton, P. Leslie

    2014-09-30

    This invention provides heme-containing peptides capable of binding molecular oxygen at room temperature. These compounds may be useful in the absorption of molecular oxygen from molecular oxygen-containing atmospheres. Also included in the invention are methods for treating an oxygen transport deficiency in a mammal.

  19. Storing and transporting energy

    DOE Patents [OSTI]

    McClaine, Andrew W. (Lexington, MA); Brown, Kenneth (Reading, MA)

    2010-09-07

    Among other things, hydrogen is released from water at a first location using energy from a first energy source; the released hydrogen is stored in a metal hydride slurry; and the metal hydride slurry is transported to a second location remote from the first location.

  20. "Educating transportation professionals."

    E-Print Network [OSTI]

    Zhigilei, Leonid V.

    @virginia.edu http://cts.virginia.edu/Demetsky.htm Dept. of Civil and Environmental Engineering University of Virginia Charlottesville, VA 434.924.7464 Transportation Engineering & Management Research Our group works and Operations The mobility of freight is vital to the national economy. The growth in demand for freight

  1. Ionic (Proton) Transport Hydrogen

    E-Print Network [OSTI]

    environments - #12;Technology Options -- Ionic Transport Separation Systems Central, Semi-Central (coal/Semi-Central Systems Coal is the cheapest fuel, but requires the greatest pre-conditioning Clean-up of syngas requires Energy Systems ChevronTexaco SRI Consulting SAIC ChevronTexaco Technology Ventures #12;Performance

  2. Climate Change and Transportation

    E-Print Network [OSTI]

    Minnesota, University of

    1 Climate Change and Transportation Addressing Climate Change in the Absence of Federal Guidelines;6 WSDOT Efforts · Climate Change Team · Project Level GHG Approach · Planning Level GHG Approach · Alternative Fuels Corridor · Recent legislation and research #12;7 WSDOT Efforts: Climate Change Team

  3. Saturated Zone Colloid Transport

    SciTech Connect (OSTI)

    H. S. Viswanathan

    2004-10-07

    This scientific analysis provides retardation factors for colloids transporting in the saturated zone (SZ) and the unsaturated zone (UZ). These retardation factors represent the reversible chemical and physical filtration of colloids in the SZ. The value of the colloid retardation factor, R{sub col} is dependent on several factors, such as colloid size, colloid type, and geochemical conditions (e.g., pH, Eh, and ionic strength). These factors are folded into the distributions of R{sub col} that have been developed from field and experimental data collected under varying geochemical conditions with different colloid types and sizes. Attachment rate constants, k{sub att}, and detachment rate constants, k{sub det}, of colloids to the fracture surface have been measured for the fractured volcanics, and separate R{sub col} uncertainty distributions have been developed for attachment and detachment to clastic material and mineral grains in the alluvium. Radionuclides such as plutonium and americium sorb mostly (90 to 99 percent) irreversibly to colloids (BSC 2004 [DIRS 170025], Section 6.3.3.2). The colloid retardation factors developed in this analysis are needed to simulate the transport of radionuclides that are irreversibly sorbed onto colloids; this transport is discussed in the model report ''Site-Scale Saturated Zone Transport'' (BSC 2004 [DIRS 170036]). Although it is not exclusive to any particular radionuclide release scenario, this scientific analysis especially addresses those scenarios pertaining to evidence from waste-degradation experiments, which indicate that plutonium and americium may be irreversibly attached to colloids for the time scales of interest. A section of this report will also discuss the validity of using microspheres as analogs to colloids in some of the lab and field experiments used to obtain the colloid retardation factors. In addition, a small fraction of colloids travels with the groundwater without any significant retardation. Radionuclides irreversibly sorbed onto this fraction of colloids also transport without retardation. The transport times for these radionuclides will be the same as those for nonsorbing radionuclides. The fraction of nonretarding colloids developed in this analysis report is used in the abstraction of SZ and UZ transport models in support of the total system performance assessment (TSPA) for the license application (LA). This analysis report uses input from two Yucca Mountain Project (YMP) analysis reports. This analysis uses the assumption from ''Waste Form and In-Drift Colloids-Associated Radionuclide Concentrations: Abstraction and Summary'' that plutonium and americium are irreversibly sorbed to colloids generated by the waste degradation processes (BSC 2004 [DIRS 170025]). In addition, interpretations from RELAP analyses from ''Saturated Zone In-Situ Testing'' (BSC 2004 [DIRS 170010]) are used to develop the retardation factor distributions in this analysis.

  4. Drug testing example for conditional probability Suppose that a drug test for an illegal drug is such that it is 98% accurate in the case of a

    E-Print Network [OSTI]

    Gross, Louis J.

    Drug testing example for conditional probability Suppose that a drug test for an illegal drug is such that it is 98% accurate in the case of a user of that drug (e.g. it produces a positive result with probability .98 in the case that the tested individual uses the drug) and 90% accurate in the case of a non

  5. Drug testing example for conditional probability Suppose that a drug test for an illegal drug is such that it is 98% accurate in the case of a

    E-Print Network [OSTI]

    Gross, Louis J.

    Drug testing example for conditional probability Suppose that a drug test for an illegal drug .98 in the case that the tested individual uses the drug) and 90% accurate in the case of a non it is known that 10% of the entire population uses this drug. You test someone and the test is positive. What

  6. A Transport Synthetic Acceleration method for transport iterations 

    E-Print Network [OSTI]

    Ramone, Gilles Lionel

    1996-01-01

    We present a family of Transport Synthetic Acceleration (TSA) methods to iteratively solve within-group scattering problems. A single iteration in these schemes consists of a transport sweep followed by a low-order calculation ...

  7. 35 Alternative Transportation Fuels in California ALTERNATIVE TRANSPORTATION

    E-Print Network [OSTI]

    potential means for diversifying an energy resource base for the transportation sector. Largely as a result, there is a potential for the entrance of an estimated one million alternative fuel vehicles (AFVs) into the California35 Alternative Transportation Fuels in California Chapter 4 ALTERNATIVE TRANSPORTATION FUELS

  8. Integrated transportation system design optimization

    E-Print Network [OSTI]

    Taylor, Christine P. (Christine Pia), 1979-

    2007-01-01

    Traditionally, the design of a transportation system has focused on either the vehicle design or the network flow, assuming the other as given. However, to define a system level architecture for a transportation system, ...

  9. Emerging pathogens: Dynamics, mutation and drug resistance

    SciTech Connect (OSTI)

    Perelson, A.S.; Goldstein, B.; Korber, B.T. [and others

    1997-10-01

    This is the final report of a one-year, Laboratory Directed Research and Development (LDRD) project at Los Alamos National Laboratory (LANL). The objectives of this project were to develop models of the spread of pathogens, such as HIV-1 and influenza, in humans, and then to use the models to address the possibility of designing appropriate drug therapies that may limit the ability of the pathogen to escape treatment by mutating into a drug resistant form. We have developed a model of drug-resistance to amantidine and rimantadine, the two major antiviral drugs used to treat influenza, and have used the model to suggest treatment strategies during an epidemic.

  10. Automated High Throughput Drug Target Crystallography

    SciTech Connect (OSTI)

    Rupp, B

    2005-02-18

    The molecular structures of drug target proteins and receptors form the basis for 'rational' or structure guided drug design. The majority of target structures are experimentally determined by protein X-ray crystallography, which as evolved into a highly automated, high throughput drug discovery and screening tool. Process automation has accelerated tasks from parallel protein expression, fully automated crystallization, and rapid data collection to highly efficient structure determination methods. A thoroughly designed automation technology platform supported by a powerful informatics infrastructure forms the basis for optimal workflow implementation and the data mining and analysis tools to generate new leads from experimental protein drug target structures.

  11. Analysis of Assembly Bill 310: Prescription Drugs

    E-Print Network [OSTI]

    California Health Benefits Review Program (CHBRP)

    2011-01-01

    drugs related to infertility treatment (for those plans thatloss treatments; infertility treatments; smoking cessationfor the treatment of sexual dysfunction and infertility). In

  12. Transport Properties of Bilayer Graphene Nanoribbons

    E-Print Network [OSTI]

    Wang, Minsheng

    2013-01-01

    Electrical spin injection and transport in germanium”. Phys.P. , Temperature- Dependent Transport in Suspended Graphene.Y. M. , Quantum Transport: Introduction to Nanoscience.

  13. Contaminant Transport in the Southern California Bight

    E-Print Network [OSTI]

    Idica, Eileen Y.

    2010-01-01

    1987). The California Current transports Pacific Subarctic1987). The California Current transports Pacific Subarcticthe dynamics and transport of Southern California stormwater

  14. Computational Method for Drug Target Search and Application in Drug Discovery

    E-Print Network [OSTI]

    Chen, Yuzong

    Ligand-protein inverse docking has recently been introduced as a computer method for identification of potential protein targets of a drug. A protein structure database is searched to find proteins to which a drug can bind ...

  15. Transforming California's Freight Transport System

    E-Print Network [OSTI]

    California at Davis, University of

    Transforming California's Freight Transport System Policy Forum on the Role of Freight Transport in Achieving Clean Air, Climate Goals, Economic Growth and Healthy Communities in California Jack Kitowski April 19, 2013 1 #12;Freight Impacts at Many Levels 2 #12;Freight Transport Today: Contribution

  16. Parallel Transports in Webs

    E-Print Network [OSTI]

    Christian Fleischhack

    2003-07-17

    For connected reductive linear algebraic structure groups it is proven that every web is holonomically isolated. The possible tuples of parallel transports in a web form a Lie subgroup of the corresponding power of the structure group. This Lie subgroup is explicitly calculated and turns out to be independent of the chosen local trivializations. Moreover, explicit necessary and sufficient criteria for the holonomical independence of webs are derived. The results above can even be sharpened: Given an arbitrary neighbourhood of the base points of a web, then this neighbourhood contains some segments of the web whose parameter intervals coincide, but do not include 0 (that corresponds to the base points of the web), and whose parallel transports already form the same Lie subgroup as those of the full web do.

  17. Fuel cell water transport

    DOE Patents [OSTI]

    Vanderborgh, Nicholas E. (Los Alamos, NM); Hedstrom, James C. (Los Alamos, NM)

    1990-01-01

    The moisture content and temperature of hydrogen and oxygen gases is regulated throughout traverse of the gases in a fuel cell incorporating a solid polymer membrane. At least one of the gases traverses a first flow field adjacent the solid polymer membrane, where chemical reactions occur to generate an electrical current. A second flow field is located sequential with the first flow field and incorporates a membrane for effective water transport. A control fluid is then circulated adjacent the second membrane on the face opposite the fuel cell gas wherein moisture is either transported from the control fluid to humidify a fuel gas, e.g., hydrogen, or to the control fluid to prevent excess water buildup in the oxidizer gas, e.g., oxygen. Evaporation of water into the control gas and the control gas temperature act to control the fuel cell gas temperatures throughout the traverse of the fuel cell by the gases.

  18. Rail transportation update

    SciTech Connect (OSTI)

    Buchsbaum, L.

    2009-01-15

    Record western coal shipments and lucrative export traffic lead America's railroad to their fourth most profitable year in history. But with the coal boom going bust, higher rates, and a new administration and congress, what sort of transportation year can coal mines and shippers expect in 2009? The article gives the opinions of company executives and discusses findings of the recent so-called Christenson Report which investigated growing railroad market power. 1 ref., 1 fig.

  19. Multiscale thermal transport.

    SciTech Connect (OSTI)

    Graham, Samuel Jr. (; .); Wong, C. C.; Piekos, Edward Stanley

    2004-02-01

    A concurrent computational and experimental investigation of thermal transport is performed with the goal of improving understanding of, and predictive capability for, thermal transport in microdevices. The computational component involves Monte Carlo simulation of phonon transport. In these simulations, all acoustic modes are included and their properties are drawn from a realistic dispersion relation. Phonon-phonon and phonon-boundary scattering events are treated independently. A new set of phonon-phonon scattering coefficients are proposed that reflect the elimination of assumptions present in earlier analytical work from the simulation. The experimental component involves steady-state measurement of thermal conductivity on silicon films as thin as 340nm at a range of temperatures. Agreement between the experiment and simulation on single-crystal silicon thin films is excellent, Agreement for polycrystalline films is promising, but significant work remains to be done before predictions can be made confidently. Knowledge gained from these efforts was used to construct improved semiclassical models with the goal of representing microscale effects in existing macroscale codes in a computationally efficient manner.

  20. Transportation of medical isotopes

    SciTech Connect (OSTI)

    Nielsen, D.L.

    1997-11-19

    A Draft Technical Information Document (HNF-1855) is being prepared to evaluate proposed interim tritium and medical isotope production at the Fast Flux Test Facility (FFTF). This assessment examines the potential health and safety impacts of transportation operations associated with the production of medical isotopes. Incident-free and accidental impacts are assessed using bounding source terms for the shipment of nonradiological target materials to the Hanford Site, the shipment of irradiated targets from the FFTF to the 325 Building, and the shipment of medical isotope products from the 325 Building to medical distributors. The health and safety consequences to workers and the public from the incident-free transportation of targets and isotope products would be within acceptable levels. For transportation accidents, risks to works and the public also would be within acceptable levels. This assessment is based on best information available at this time. As the medical isotope program matures, this analysis will be revised, if necessary, to support development of a final revision to the Technical Information Document.

  1. Large-scale prediction of adverse drug reactions using chemical, biological, and phenotypic properties of drugs

    E-Print Network [OSTI]

    Liu, Mei; Wu, Yonghui; Chen, Yukun; Sun, Jingchun; Zhao, Zhongming; Chen, Xue-wen; Matheny, Michael Edwin; Xu, Hua

    2012-06-19

    Abstract Objective Adverse drug reaction (ADR) is one of the major causes of failure in drug development. Severe ADRs that go undetected until the post-marketing phase of a drug often lead to patient morbidity. Accurate prediction of potential ADRs...

  2. Drug Testing Notification Form RV 2 May 22, 2013 DRUG TESTING NOTIFICATION FORM

    E-Print Network [OSTI]

    Drug Testing Notification Form RV 2 May 22, 2013 DRUG TESTING NOTIFICATION FORM Section 1: Employer testing collector. You are required to undergo urine drug testing as a condition of hiring. You must have of Collection: ___________________________ Date and time of Test* * For testing out side of Louisiana testing

  3. Transportation Energy Futures Analysis Snapshot

    Broader source: Energy.gov [DOE]

    Transportation currently accounts for 71% of total U.S. petroleum use and 33% of the nation's total carbon emissions. The TEF project explores how combining multiple strategies could reduce GHG emissions and petroleum use by 80%. Researchers examined four key areas – lightduty vehicles, non-light-duty vehicles, fuels, and transportation demand – in the context of the marketplace, consumer behavior, industry capabilities, technology and the energy and transportation infrastructure. The TEF reports support DOE long-term planning. The reports provide analysis to inform decisions about transportation energy research investments, as well as the role of advanced transportation energy technologies and systems in the development of new physical, strategic, and policy alternatives.

  4. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect (OSTI)

    Stefan Miska; Troy Reed; Ergun Kuru

    2004-09-30

    The Advanced Cuttings Transport Study (ACTS) was a 5-year JIP project undertaken at the University of Tulsa (TU). The project was sponsored by the U.S. Department of Energy (DOE) and JIP member companies. The objectives of the project were: (1) to develop and construct a new research facility that would allow three-phase (gas, liquid and cuttings) flow experiments under ambient and EPET (elevated pressure and temperature) conditions, and at different angle of inclinations and drill pipe rotation speeds; (2) to conduct experiments and develop a data base for the industry and academia; and (3) to develop mechanistic models for optimization of drilling hydraulics and cuttings transport. This project consisted of research studies, flow loop construction and instrumentation development. Following a one-year period for basic flow loop construction, a proposal was submitted by TU to the DOE for a five-year project that was organized in such a manner as to provide a logical progression of research experiments as well as additions to the basic flow loop. The flow loop additions and improvements included: (1) elevated temperature capability; (2) two-phase (gas and liquid, foam etc.) capability; (3) cuttings injection and removal system; (4) drill pipe rotation system; and (5) drilling section elevation system. In parallel with the flow loop construction, hydraulics and cuttings transport studies were preformed using drilling foams and aerated muds. In addition, hydraulics and rheology of synthetic drilling fluids were investigated. The studies were performed under ambient and EPET conditions. The effects of temperature and pressure on the hydraulics and cuttings transport were investigated. Mechanistic models were developed to predict frictional pressure loss and cuttings transport in horizontal and near-horizontal configurations. Model predictions were compared with the measured data. Predominantly, model predictions show satisfactory agreements with the measured data. As a part of this project, instrumentation was developed to monitor cuttings beds and characterize foams in the flow loop. An ultrasonic-based monitoring system was developed to measure cuttings bed thickness in the flow loop. Data acquisition software controls the system and processes the data. Two foam generating devices were designed and developed to produce foams with specified quality and texture. The devices are equipped with a bubble recognition system and an in-line viscometer to measure bubble size distribution and foam rheology, respectively. The 5-year project is completed. Future research activities will be under the umbrella of Tulsa University Drilling Research Projects. Currently the flow loop is being used for testing cuttings transport capacity of aqueous and polymer-based foams under elevated pressure and temperature conditions. Subsequently, the effect of viscous sweeps on cuttings transport under elevated pressure and temperature conditions will be investigated using the flow loop. Other projects will follow now that the ''steady state'' phase of the project has been achieved.

  5. Antiplatelet and Anticoagulant Drugs in Interventional Radiology

    SciTech Connect (OSTI)

    Altenburg, Alexander; Haage, Patrick, E-mail: patrick.haage@helios-kliniken.de [University Hospital Witten/Herdecke, Department of Diagnostic and Interventional Radiology, HELIOS Klinikum Wuppertal (Germany)

    2012-02-15

    In treating peripheral arterial disease, a profound knowledge of antiplatelet and anticoagulative drug therapy is helpful to assure a positive clinical outcome and to anticipate and avoid complications. Side effects and drug interactions may have fatal consequences for the patient, so interventionalists should be aware of these risks and able to control them. Aspirin remains the first-line agent for antiplatelet monotherapy, with clopidogrel added where dual antiplatelet therapy is required. In case of suspected antiplatelet drug resistance, the dose of clopidogrel may be doubled; prasugrel or ticagrelor may be used alternatively. Glycoprotein IIb/IIIa inhibitors (abciximab or eptifibatide) may help in cases of hypercoagulability or acute embolic complications. Desmopressin, tranexamic acid, or platelet infusions may be used to decrease antiplatelet drug effects in case of bleeding. Intraprocedurally, anticoagulant therapy treatment with unfractionated heparin (UFH) still is the means of choice, although low molecular-weight heparins (LMWH) are suitable, particularly for postinterventional treatment. Adaption of LMWH dose is often required in renal insufficiency, which is frequently found in elderly patients. Protamine sulphate is an effective antagonist for UFH; however, this effect is less for LMWH. Newer antithrombotic drugs, such as direct thrombin inhibitors or factor X inhibitors, have limited importance in periprocedural treatment, with the exception of treating patients with heparin-induced thrombocytopenia (HIT). Nevertheless, knowing pharmacologic properties of the newer drugs facilitate correct bridging of patients treated with such drugs. This article provides a comprehensive overview of antiplatelet and anticoagulant drugs for use before, during, and after interventional radiological procedures.

  6. Pricing in the Market for Anticancer Drugs

    E-Print Network [OSTI]

    Howard, David H.

    In 2011, Bristol-Myers Squibb set the price of its newly approved melanoma drug ipilimumab— brand name Yervoy—at $120,000 for a course of therapy. The drug was associated with an incremental increase in life expectancy of ...

  7. Transport optimization in stellaratorsa... H. E. Mynickb

    E-Print Network [OSTI]

    Mynick, Harry E.

    Transport optimization in stellaratorsa... H. E. Mynickb Plasma Physics Laboratory, Princeton transport in stellarators is presented. A primary deficiency of stellarators has been elevated transport this difficulty, developing a range of techniques for reducing transport, both neoclassical and, more recently

  8. Illegal Drugs Policy Swansea University and Students' Union

    E-Print Network [OSTI]

    Martin, Ralph R.

    Illegal Drugs Policy Swansea University and Students' Union #12;Illegal Drugs Policy for Swansea University and Students' Union Table of Contents Page Drugs Policy Statement 2 Drugs Policy 3 1. Introduction 2. Who is covered by the policy? 3. Aims of the policy 5. What do we mean by illegal drugs? 4

  9. Update on EM Transportation Program Activities

    Office of Environmental Management (EM)

    Organizations * DOE Orders, Policy, Guidance Transportation Risk Reduction * Motor Carrier Evaluations * Physical Protection * Transportation Compliance Reviews * Safety...

  10. Supertruck - Improving Transportation Efficiency through Integrated...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Improving Transportation Efficiency through Integrated Vehicle, Engine and Powertrain Research Supertruck - Improving Transportation Efficiency through Integrated Vehicle, Engine...

  11. Department of Transportation Pipeline and Hazardous Materials...

    Office of Environmental Management (EM)

    Transportation Pipeline and Hazardous Materials Safety Administration Activities Department of Transportation Pipeline and Hazardous Materials Safety Administration Activities...

  12. Africa's Transport Infrastructure Mainstreaming Maintenance and...

    Open Energy Info (EERE)

    Africa's Transport Infrastructure Mainstreaming Maintenance and Management Jump to: navigation, search Tool Summary LAUNCH TOOL Name: Africa's Transport Infrastructure...

  13. Transportation and Stationary Power Integration Workshop Session...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Transportation and Stationary Power Integration Workshop Agenda, October 27, 2008, Phoenix, Arizonia Transportation and Stationary Power Integration: Workshop Proceedings...

  14. Enhancing Transportation Energy Security through Advanced Combustion...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Transportation Energy Security through Advanced Combustion and Fuels Technologies Enhancing Transportation Energy Security through Advanced Combustion and Fuels Technologies 2005...

  15. The Department of Energy`s Rocky Flats Plant: A guide to record series useful for health-related research. Volume VI, workplace and environmental monitoring

    SciTech Connect (OSTI)

    1995-08-01

    This is the sixth in a series of seven volumes which constitute a guide to records of the Rocky Flats Plant useful for conducting health-related research. The primary purpose of Volume VI is to describe record series pertaining to workplace and environmental monitoring activities at the Department of Energy`s (DOE) Rocky Flats Plant, now named the Rocky Flats Environmental Technology Site, near Denver, Colorado. History Associates Incorporated (HAI) prepared this guide as part of its work as the support services contractor for DOE`s Epidemiologic Records Inventory Project. This introduction briefly describes the Epidemiologic Records Inventory Project and HAI`s role in the project, provides a history of workplace and environmental monitoring practices at Rocky Flats, and identifies organizations contributing to workplace and environmental monitoring policies and activities. Other topics include the scope and arrangement of this volume and the organization to contact for access to these records. Comprehensive introductory and background information is available in Volume I. Other volumes in the guide pertain to administrative and general subjects, facilities and equipment, production and materials handling, waste management, and employee health. In addition, HAI has produced a subject-specific guide, titled The September 1957 Rocky Flats Fire. A Guide to Record Series of the Department of Energy and Its Contractors, which researchers should consult for further information about records related to this incident.

  16. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect (OSTI)

    Ergun Kuru; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Gerald Kane; Mark Pickell; Len Volk; Mike Volk; Barkim Demirdal; Affonso Lourenco; Evren Ozbayoglu; Paco Vieira; Neelima Godugu

    2000-07-30

    ACTS flow loop is now operational under elevated pressure and temperature. Currently, experiments with synthetic based drilling fluids under pressure and temperature are being conducted. Based on the analysis of Fann 70 data, empirical correlations defining the shear stress as a function of temperature, pressure and the shear rate have been developed for Petrobras synthetic drilling fluids. PVT equipment has been modified for testing Synthetic oil base drilling fluids. PVT tests with Petrobras Synthetic base mud have been conducted and results are being analyzed Foam flow experiments have been conducted and the analysis of the data has been carried out to characterize the rheology of the foam. Comparison of pressure loss prediction from the available foam hydraulic models and the test results has been made. Cuttings transport experiments in horizontal annulus section have been conducted using air, water and cuttings. Currently, cuttings transport tests in inclined test section are being conducted. Foam PVT analysis tests have been conducted. Foam stability experiments have also been conducted. Effects of salt and oil concentration on the foam stability have been investigated. Design of ACTS flow loop modification for foam and aerated mud flow has been completed. A flow loop operation procedure for conducting foam flow experiments under EPET conditions has been prepared Design of the lab-scale flow loop for dynamic foam characterization and cuttings monitoring instrumentation tests has been completed. The construction of the test loop is underway. As part of the technology transport efforts, Advisory Board Meeting with ACTS-JIP industry members has been organized on May 13, 2000.

  17. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect (OSTI)

    Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Mengjiao Yu; Ramadan Ahmed; Mark Pickell; Len Volk; Lei Zhou; Zhu Chen; Aimee Washington; Crystal Redden

    2003-09-30

    The Quarter began with installing the new drill pipe, hooking up the new hydraulic power unit, completing the pipe rotation system (Task 4 has been completed), and making the SWACO choke operational. Detailed design and procurement work is proceeding on a system to elevate the drill-string section. The prototype Foam Generator Cell has been completed by Temco and delivered. Work is currently underway to calibrate the system. Literature review and preliminary model development for cuttings transportation with polymer foam under EPET conditions are in progress. Preparations for preliminary cuttings transport experiments with polymer foam have been completed. Two nuclear densitometers were re-calibrated. Drill pipe rotation system was tested up to 250 RPM. Water flow tests were conducted while rotating the drill pipe up to 100 RPM. The accuracy of weight measurements for cuttings in the annulus was evaluated. Additional modifications of the cuttings collection system are being considered in order to obtain the desired accurate measurement of cuttings weight in the annular test section. Cutting transport experiments with aerated fluids are being conducted at EPET, and analyses of the collected data are in progress. The printed circuit board is functioning with acceptable noise level to measure cuttings concentration at static condition using ultrasonic method. We were able to conduct several tests using a standard low pass filter to eliminate high frequency noise. We tested to verify that we can distinguish between different depths of sand in a static bed of sand. We tested with water, air and a mix of the two mediums. Major modifications to the DTF have almost been completed. A stop-flow cell is being designed for the DTF, the ACTF and Foam Generator/Viscometer which will allow us to capture bubble images without the need for ultra fast shutter speeds or microsecond flash system.

  18. Resolving the mystery of transport within internal transport barriers

    SciTech Connect (OSTI)

    Staebler, G. M.; Belli, E. A.; Candy, J.; Waltz, R. E.; Greenfield, C. M.; Lao, L. L.; Smith, S. P.; Kinsey, J. E.; Grierson, B. A.; Chrystal, C.

    2014-05-15

    The Trapped Gyro-Landau Fluid (TGLF) quasi-linear model [G. M. Staebler, et al., Phys. Plasmas 12, 102508 (2005)], which is calibrated to nonlinear gyrokinetic turbulence simulations, is now able to predict the electron density, electron and ion temperatures, and ion toroidal rotation simultaneously for internal transport barrier (ITB) discharges. This is a strong validation of gyrokinetic theory of ITBs, requiring multiple instabilities responsible for transport in different channels at different scales. The mystery of transport inside the ITB is that momentum and particle transport is far above the predicted neoclassical levels in apparent contradiction with the expectation from the theory of suppression of turbulence by E×B velocity shear. The success of TGLF in predicting ITB transport is due to the inclusion of ion gyro-radius scale modes that become dominant at high E×B velocity shear and to improvements to TGLF that allow momentum transport from gyrokinetic turbulence to be faithfully modeled.

  19. Transportation | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservationBio-Inspired SolarAbout / Transforming Y-12Capacity-ForumTransportation

  20. Transportation | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION JEnvironmental Jump to:EA EISTJThin Film SolarTown ofTransportToolkit Prototype Jump

  1. Transportation Fuel Supply | NISAC

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorking With U.S.WeekProducts >Transportation currently accounts for

  2. Transportation Representation | NISAC

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorking With U.S.WeekProducts >Transportation currently

  3. Transportation and Parking

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorking With U.S.WeekProducts >Transportation

  4. Electron Heat Transport Measured

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submitKansas Nuclear ProfileMultiferroicAward |Electron CorrelationHeat Transport

  5. Sandia Energy - Transportation Energy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservation of Fe(II)GeothermalFuel MagnetizationTransportation Energy Home Analysis Final

  6. Sandia Energy - Transportation Safety

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservation of Fe(II)GeothermalFuel MagnetizationTransportation Energy Home

  7. Modeling Multiple Drugs on Lung Cancer and Normal Cells using Regression

    E-Print Network [OSTI]

    Chen, Michelle

    2013-01-01

    Drug Combination . . . . . . . . . . . . . . . .n 27 vii List of Tables Drug Concentration . . . . . . .Factorial Designs in Antiviral Drug Stud- ies. ” Quality and

  8. An implantable device for localized drug delivery and sensing

    E-Print Network [OSTI]

    Daniel, Karen D

    2009-01-01

    There are many potential clinical applications for localized drug delivery and sensing systems, such as cancer, vaccinations, pain management, and hormone therapy. Localized drug delivery systems reduce the amount of drug ...

  9. Ancient Proteins Help Unravel a Modern Cancer Drug's Mechanism

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Ancient Proteins Help Unravel a Modern Cancer Drug's Mechanism Ancient Proteins Help Unravel a Modern Cancer Drug's Mechanism Print Tuesday, 23 June 2015 13:00 The cancer drug...

  10. Prescription Drug Monitoring Programs: Examining Limitations and Future Approaches

    E-Print Network [OSTI]

    Griggs, Christopher A.; Weiner, Scott G.; Feldman, James A.

    2015-01-01

    Li G, Brady JE, Lang B, et al. Prescription drug monitoringand drug overdose mortality. Inj Epidemiol. 2014;1:1-9.EM, Desai HA. Prescription drug monitoring programs and

  11. Drugs in Cinema: Separating the Myths from Reality

    E-Print Network [OSTI]

    Iannicelli, Paul

    2001-01-01

    Introduction: The Evolution of Drug Abuse in Americain HAND- BOOK OF DRUG CONTROL IN THE UNITED STATES (James A.See JOSEPH SPILLANE, MODERN DRUG, MODERN MENANCE 214 (1994).

  12. Optimizing Combination Therapies with Existing and Future CML Drugs

    E-Print Network [OSTI]

    Katouli, Allen A.; Komarova, Natalia L.

    2010-01-01

    kinase inhibitors. Nat Rev Drug Discov 3: 1001–10. 12.screen: high efficacy of drug combinations. Blood 108: 2332–Abl kinase domain mutations, drug resistance, and the road

  13. ELECTROCHEMICAL POWER FOR TRANSPORTATION

    SciTech Connect (OSTI)

    Cairns, Elton J.; Hietbrink, Earl H.

    1981-01-01

    This section includes some historical background of the rise and fall and subsequent rebirth of the electric vehicle; and a brief discussion of current transportation needs, and environmental and energy utilization issues that resulted in the renewed interest in applying electrochemical energy conversion technology to electric vehicle applications. Although energy utilization has evolved to be the most significant and important issue, the environmental issue will be discussed first in this section only because of its chronological occurrence. The next part of the chapter is a review of passenger and commercial electric vehicle technology with emphasis on vehicle design and demonstrated performance of vehicles with candidate power sources being developed. This is followed by a discussion of electrochemical power source requirements associated with future electric vehicles that can play a role in meeting modern transportation needs. The last part of the chapter includes first a discussion of how to identify candidate electrochemical systems that might be of interest in meeting electric vehicle power source requirements. This is then followed by a review of the current technological status of these systems and a discussion of the most significant problems that must be resolved before each candidate system can be a viable power source.

  14. ADVANCED CUTTINGS TRANSPORT STUDY

    SciTech Connect (OSTI)

    Troy Reed; Stefan Miska; Nicholas Takach; Kaveh Ashenayi; Mark Pickell; Len Volk; Mike Volk; Lei Zhou; Zhu Chen; Crystal Redden; Aimee Washington

    2003-07-30

    This Quarter has been divided between running experiments and the installation of the drill-pipe rotation system. In addition, valves and piping were relocated, and three viewports were installed. Detailed design work is proceeding on a system to elevate the drill-string section. Design of the first prototype version of a Foam Generator has been finalized, and fabrication is underway. This will be used to determine the relationship between surface roughness and ''slip'' of foams at solid boundaries. Additional cups and rotors are being machined with different surface roughness. Some experiments on cuttings transport with aerated fluids have been conducted at EPET. Theoretical modeling of cuttings transport with aerated fluids is proceeding. The development of theoretical models to predict frictional pressure losses of flowing foam is in progress. The new board design for instrumentation to measure cuttings concentration is now functioning with an acceptable noise level. The ultrasonic sensors are stable up to 190 F. Static tests with sand in an annulus indicate that the system is able to distinguish between different sand concentrations. Viscometer tests with foam, generated by the Dynamic Test Facility (DTF), are continuing.

  15. OXYGEN TRANSPORT CERAMIC MEMBRANES

    SciTech Connect (OSTI)

    Dr. Sukumar Bandopadhyay; Dr. Nagendra Nagabhushana

    2000-10-01

    This is the third quarterly report on oxygen Transport Ceramic Membranes. In the following, the report describes the progress made by our university partners in Tasks 1 through 6, experimental apparatus that was designed and built for various tasks of this project, thermodynamic calculations, where applicable and work planned for the future. (Task 1) Design, fabricate and evaluate ceramic to metal seals based on graded ceramic powder/metal braze joints. (Task 2) Evaluate the effect of defect configuration on ceramic membrane conductivity and long term chemical and structural stability. (Task 3) Determine materials mechanical properties under conditions of high temperatures and reactive atmospheres. (Task 4) Evaluate phase stability and thermal expansion of candidate perovskite membranes and develop techniques to support these materials on porous metal structures. (Task 5) Assess the microstructure of membrane materials to evaluate the effects of vacancy-impurity association, defect clusters, and vacancy-dopant association on the membrane performance and stability. (Task 6) Measure kinetics of oxygen uptake and transport in ceramic membrane materials under commercially relevant conditions using isotope labeling techniques.

  16. Transportation Statistics Annual Report 1997

    SciTech Connect (OSTI)

    Fenn, M.

    1997-01-01

    This document is the fourth Transportation Statistics Annual Report (TSAR) prepared by the Bureau of Transportation Statistics (BTS) for the President and Congress. As in previous years, it reports on the state of U.S. transportation system at two levels. First, in Part I, it provides a statistical and interpretive survey of the system—its physical characteristics, its economic attributes, aspects of its use and performance, and the scale and severity of unintended consequences of transportation, such as fatalities and injuries, oil import dependency, and environment impacts. Part I also explores the state of transportation statistics, and new needs of the rapidly changing world of transportation. Second, Part II of the report, as in prior years, explores in detail the performance of the U.S. transportation system from the perspective of desired social outcomes or strategic goals. This year, the performance aspect of transportation chosen for thematic treatment is “Mobility and Access,” which complements past TSAR theme sections on “The Economic Performance of Transportation” (1995) and “Transportation and the Environment” (1996). Mobility and access are at the heart of the transportation system’s performance from the user’s perspective. In what ways and to what extent does the geographic freedom provided by transportation enhance personal fulfillment of the nation’s residents and contribute to economic advancement of people and businesses? This broad question underlies many of the topics examined in Part II: What is the current level of personal mobility in the United States, and how does it vary by sex, age, income level, urban or rural location, and over time? What factors explain variations? Has transportation helped improve people’s access to work, shopping, recreational facilities, and medical services, and in what ways and in what locations? How have barriers, such as age, disabilities, or lack of an automobile, affected these accessibility patterns? How are commodity flows and transportation services responding to global competition, deregulation, economic restructuring, and new information technologies? How do U.S. patterns of personal mobility and freight movement compare with other advanced industrialized countries, formerly centrally planned economies, and major newly industrializing countries? Finally, how is the rapid adoption of new information technologies influencing the patterns of transportation demand and the supply of new transportation services? Indeed, how are information technologies affecting the nature and organization of transportation services used by individuals and firms?

  17. Nanoengineered membranes for controlled transport

    DOE Patents [OSTI]

    Doktycz, Mitchel J. (Oak Ridge, TN) [Oak Ridge, TN; Simpson, Michael L. (Knoxville, TN) [Knoxville, TN; McKnight, Timothy E. (Greenback, TN) [Greenback, TN; Melechko, Anatoli V. (Oak Ridge, TN) [Oak Ridge, TN; Lowndes, Douglas H. (Knoxville, TN) [Knoxville, TN; Guillorn, Michael A. (Knoxville, TN) [Knoxville, TN; Merkulov, Vladimir I. (Oak Ridge, TN) [Oak Ridge, TN

    2010-01-05

    A nanoengineered membrane for controlling material transport (e.g., molecular transport) is disclosed. The membrane includes a substrate, a cover definining a material transport channel between the substrate and the cover, and a plurality of fibers positioned in the channel and connected to an extending away from a surface of the substrate. The fibers are aligned perpendicular to the surface of the substrate, and have a width of 100 nanometers or less. The diffusion limits for material transport are controlled by the separation of the fibers. In one embodiment, chemical derivitization of carbon fibers may be undertaken to further affect the diffusion limits or affect selective permeability or facilitated transport. For example, a coating can be applied to at least a portion of the fibers. In another embodiment, individually addressable carbon nanofibers can be integrated with the membrane to provide an electrical driving force for material transport.

  18. Resistance proof, folding-inhibitor drugs

    E-Print Network [OSTI]

    R. Broglia; G. Tiana; R. Berera

    2002-10-09

    Conventional drugs work, as a rule, by inhibiting the enzymatic activity of specific proteins, capping their active site. In this paper we present a model of non- conventional drug design based on the inhibiting effects small peptides obtained from segments of the protein itself have on the folding ability of the system. Such peptides attach to the newly expressed (unfolded) protein and inhibit its folding, inhibition which cannot be avoided but through mutations which in any case denaturate the enzyme. These peptides, or their mimetic molecules, can be used as effective alternative drugs to those already available, displaying the advantage of not suffering from the upraise of resistence.

  19. From the Frontlines to the Bottom Line: Medical Marijuana, the War on Drugs, and the Drug Policy Reform Movement

    E-Print Network [OSTI]

    Heddleston, Thomas Reed

    2012-01-01

    International Journal of Drug Policy 10: 319-28. Zinberg,Norman E. 1984. Drug, Set, and Setting: The Basis forand Mirrors: The War on Drugs and the Politics of Failure.

  20. Flow cytometry aids basic cell biology research and drug discovery

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Flow cytometry aids basic cell biology research and drug discovery Flow cytometry aids basic cell biology research and drug discovery Life Technologies Corporation and LANL have...

  1. Nanotechnology Medical Applications Breakthroughs in nanotechnology promise to revolutionize drug

    E-Print Network [OSTI]

    Hill, Wendell T.

    Nanotechnology Medical Applications Breakthroughs in nanotechnology promise to revolutionize drug's Nanotechnology Center are creating novel tools and developing new methods for crucial research areas of drug

  2. Ancient Proteins Help Unravel a Modern Cancer Drug's Mechanism

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Ancient Proteins Help Unravel a Modern Cancer Drug's Mechanism Print The cancer drug Gleevec is extremely specific, binding and inhibiting only the cancer-causing tyrosine protein...

  3. Analysis of a wet scrubber network in the air remediation of industrial workplaces: benefit for the city air quality

    E-Print Network [OSTI]

    Avveduto, Alessandro; Pace, Lorenzo; Curci, Gabriele; Monaco, Alessio; De Giovanni, Marina; Giammaria, Franco; Spanto, Giuseppe; Tripodi, Paolo

    2015-01-01

    Industrial activities carried out in confined spaces are characterized by a very specific type of air pollution. The extended exposure to this kind of pollution is often highly harmful, resulting in dramatic effects both on health and safety aspects. The indoor industrial abatement systems, adopted to purify the air, are typically applied to the emission points. The processed air is subsequently emitted outside. In this study we present the experimental results of three-stage wet scrubber systems installed in the industrial workplace of a (i) fiberglass processing plant, where the highest exposure levels to volatile compounds are nowadays today monitored,and of a (ii) waste-to-energy plant, characterized by a very high particulate matter level. The adopted technology, to be used as complementing strategy,does not require special disposal procedures and the processed air is re-emitted in the same work environment for the benefit of the work operators. The operation of the scrubbers network during the working a...

  4. Transportation and Greenhouse Gas Mitigation

    E-Print Network [OSTI]

    Lutsey, Nicholas P.; Sperling, Dan

    2008-01-01

    Summary of transportation greenhouse gas mitigation optionsof alternative fuels. Low greenhouse gas fuels Mixing ofMAC) refrigerant replacement. Greenhouse gas budgets for

  5. Heat transport within the Earth

    E-Print Network [OSTI]

    Herndon, J Marvin

    2011-01-01

    Numerous attempts have been made to interpret Earth's dynamic processes based upon heat transport concepts derived from ordinary experience. But, ordinary experience can be misleading, especially when underlain by false assumptions. Geodynamic considerations traditionally have embraced three modes of heat transport: conduction, convection, and radiation. Recently, I introduced a fourth, "mantle decompression thermal tsunami" that, I submit, is responsible for emplacing heat at the base of the Earth's crust. Here, I review thermal transport within the Earth and speculate that there might be a fifth mode: "heat channeling", involving heat transport from the core to "hot-spots" such as those that power the Hawaiian Islands and Iceland.

  6. Transportation Projects | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    share of petroleum use, carbon dioxide (a primary greenhouse gas) emissions, and air pollution, advances in fuel cell power systems for transportation could substantially improve...

  7. Transport Properties for Combustion Modeling

    E-Print Network [OSTI]

    Brown, N.J.

    2010-01-01

    a critical role in combustion processes just as chemicalparameters are essential for combustion modeling; molecularwith Application to Combustion. Transport Theor Stat 2003;

  8. TRANSPORTATION TOMORROW SURVEY DATA EXPANSION

    E-Print Network [OSTI]

    Toronto, University of

    in Transportation August 2007 #12;Table of Contents 1. Introduction and trip data associated with the households in that geographic area. The UTM coordinates belonging to each

  9. Alternative Transportation Technologies: Hydrogen, Biofuels,...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Hydrogen, Biofuels, Advanced Efficiency, and Plug-in Hybrid Electric Vehicles Alternative Transportation Technologies: Hydrogen, Biofuels, Advanced Efficiency, and Plug-in...

  10. Transportation and Greenhouse Gas Mitigation

    E-Print Network [OSTI]

    Lutsey, Nicholas P.; Sperling, Dan

    2008-01-01

    thereby contributing to energy security. Most also reducesuch as improved energy security, many transport GHGincluding energy cost savings, oil security, and pollution

  11. Institute of Transport Studies PSU Transportation Seminar, 21 May 2010

    E-Print Network [OSTI]

    Bertini, Robert L.

    of Electric Bicycles Assoc. Prof. Geoff Rose Director, ITS (Monash) Transport Theme Leader, Monash expand the role of the bicycle in the context of urban transportation · This seminar examines electric Battery technology · Sealed lead acid (SLA) ­ Well understood and cheapest ­ Heavy ­ Modest life · Nickel

  12. Computational model of local intravascular drug delivery

    E-Print Network [OSTI]

    Balakrishnan, Brinda

    2007-01-01

    Drug-eluting stents (DES) virtually eradicate the clinical phenomena of vessel restenosis; yet, they also increase the short and long term risks for stent thrombosis. To improve their safety and efficacy, it is critical ...

  13. Transdermal drug delivery by localized intervention

    E-Print Network [OSTI]

    Weaver, James C.

    Both field-confined skin electroporation and microscissioning offer minimally invasive methods for delivering drugs across skin and nail with minimal sensation. Both methods create high permeability pathways in a pain-free ...

  14. Rethinking America’s Illegal Drug Policy

    E-Print Network [OSTI]

    Donohue III, John J.

    2011-01-01

    Drugs (ESSPAOD). 2003. The ESPAD Report 2003: Alcohol andModintryckoffset. http://www.espad.org/documents/Espad/ESPAD_reports/The_2003_ESPAD_report.pdf. Fainaru, Steve, and

  15. Rethinking America’s Illegal Drug Policy

    E-Print Network [OSTI]

    Donohue III, John J.

    2011-01-01

    Throwing Away the Key or the Taxpayer’s Money? Santa Monica,sell these drugs has cost taxpayers billions of dollars eachdiffusely and the individual taxpayer cannot easily measure

  16. NEW APPROACHES IN UNDERSTANDING DRUG METABOLISM

    E-Print Network [OSTI]

    Hart, Steven N.

    2011-02-22

    Limitations in technology, such as DNA sequencing and appropriate model systems, have made it difficult to understand the genetic and non-genetic factors that influence the liver's role in metabolizing drugs. New approaches ...

  17. Climate and Transportation Solutions: Findings from the 2009 Asilomar Conference on Transportation and Energy Policy

    E-Print Network [OSTI]

    Sperling, Daniel; Cannon, James S.

    2010-01-01

    on Transportation, Energy and Policy convened in 1988. Oilon Transportation, Energy and Policy has been held at theon Transportation, Energy and Policy in July 2009 was the

  18. Climate and Transportation Solutions: Findings from the 2009 Asilomar Conference on Transportation and Energy Policy

    E-Print Network [OSTI]

    Sperling, Daniel; Cannon, James S.

    2010-01-01

    cials (AASHTO), Transport Canada, the California DepartmentA case study of California. ” Transport. Res. Part D. West,smaller transport-related carbon footprint than California,

  19. Climate and Transportation Solutions: Findings from the 2009 Asilomar Conference on Transportation and Energy Policy

    E-Print Network [OSTI]

    Sperling, Daniel; Cannon, James S.

    2010-01-01

    California Department of Transportation, the California EnergyCalifornia Energy Commission Climate and TransportationTransportation and Energy Policy, at Paci?c Grove, California.

  20. Transport in holographic superfluids

    E-Print Network [OSTI]

    Christopher P. Herzog; Nir Lisker; Piotr Surowka; Amos Yarom

    2011-01-17

    We construct a slowly varying space-time dependent holographic superfluid and compute its transport coefficients. Our solution is presented as a series expansion in inverse powers of the charge of the order parameter. We find that the shear viscosity associated with the motion of the condensate vanishes. The diffusion coefficient of the superfluid is continuous across the phase transition while its third bulk viscosity is found to diverge at the critical temperature. As was previously shown, the ratio of the shear viscosity of the normal component to the entropy density is 1/(4 pi). As a consequence of our analysis we obtain an analytic expression for the backreacted metric near the phase transition for a particular type of holographic superfluid.

  1. Heat transport system

    DOE Patents [OSTI]

    Harkness, Samuel D. (McMurray, PA)

    1982-01-01

    A falling bed of ceramic particles receives neutron irradiation from a neutron-producing plasma and thereby transports energy as heat from the plasma to a heat exchange location where the ceramic particles are cooled by a gas flow. The cooled ceramic particles are elevated to a location from which they may again pass by gravity through the region where they are exposed to neutron radiation. Ceramic particles of alumina, magnesia, silica and combinations of these materials are contemplated as high-temperature materials that will accept energy from neutron irradiation. Separate containers of material incorporating lithium are exposed to the neutron flux for the breeding of tritium that may subsequently be used in neutron-producing reactions. The falling bed of ceramic particles includes velocity partitioning between compartments near to the neutron-producing plasma and compartments away from the plasma to moderate the maximum temperature in the bed.

  2. OXYGEN TRANSPORT CERAMIC MEMBRANES

    SciTech Connect (OSTI)

    Dr. Sukumar Bandopadhyay; Dr. Nagendra Nagabhushana

    2003-01-01

    In the present quarter, experiments are presented on ceramic/metal interactions of Zirconia/Ni-B-Si system and with a thin Ti coating deposited on zirconia surface. Processing of perovskites of LSC, LSF and LSCF composition for evaluation of mechanical properties as a function of environment are begun. The studies are to be in parallel with LSFCO composition to characterize the segregation of cations and slow crack growth in environmental conditions. La{sub 1-x}Sr{sub x}FeO{sub 3-d} has also been characterized for paramagnetic ordering at room temperature and the evolution of magnetic moments as a function of temperature are investigated. Investigation on the thermodynamic properties of the membrane materials are continued to develop a complete model for the membrane transport.

  3. Hydrogen transport membranes

    DOE Patents [OSTI]

    Mundschau, Michael V.

    2005-05-31

    Composite hydrogen transport membranes, which are used for extraction of hydrogen from gas mixtures are provided. Methods are described for supporting metals and metal alloys which have high hydrogen permeability, but which are either too thin to be self supporting, too weak to resist differential pressures across the membrane, or which become embrittled by hydrogen. Support materials are chosen to be lattice matched to the metals and metal alloys. Preferred metals with high permeability for hydrogen include vanadium, niobium, tantalum, zirconium, palladium, and alloys thereof. Hydrogen-permeable membranes include those in which the pores of a porous support matrix are blocked by hydrogen-permeable metals and metal alloys, those in which the pores of a porous metal matrix are blocked with materials which make the membrane impervious to gases other than hydrogen, and cermets fabricated by sintering powders of metals with powders of lattice-matched ceramic.

  4. Transportation System Concept of Operations

    SciTech Connect (OSTI)

    N. Slater-Thompson

    2006-08-16

    The Nuclear Waste Policy Act of 1982 (NWPA), as amended, authorized the DOE to develop and manage a Federal system for the disposal of SNF and HLW. OCRWM was created to manage acceptance and disposal of SNF and HLW in a manner that protects public health, safety, and the environment; enhances national and energy security; and merits public confidence. This responsibility includes managing the transportation of SNF and HLW from origin sites to the Repository for disposal. The Transportation System Concept of Operations is the core high-level OCRWM document written to describe the Transportation System integrated design and present the vision, mission, and goals for Transportation System operations. By defining the functions, processes, and critical interfaces of this system early in the system development phase, programmatic risks are minimized, system costs are contained, and system operations are better managed, safer, and more secure. This document also facilitates discussions and understanding among parties responsible for the design, development, and operation of the Transportation System. Such understanding is important for the timely development of system requirements and identification of system interfaces. Information provided in the Transportation System Concept of Operations includes: the functions and key components of the Transportation System; system component interactions; flows of information within the system; the general operating sequences; and the internal and external factors affecting transportation operations. The Transportation System Concept of Operations reflects OCRWM's overall waste management system policies and mission objectives, and as such provides a description of the preferred state of system operation. The description of general Transportation System operating functions in the Transportation System Concept of Operations is the first step in the OCRWM systems engineering process, establishing the starting point for the lower level descriptions. of subsystems and components, and the Transportation System Requirements Document. Other program and system documents, plans, instructions, and detailed designs will be consistent with and informed by the Transportation System Concept of Operations. The Transportation System Concept of Operations is a living document, enduring throughout the OCRWM systems engineering lifecycle. It will undergo formal approval and controlled revisions as appropriate while the Transportation System matures. Revisions will take into account new policy decisions, new information available through system modeling, engineering investigations, technical analyses and tests, and the introduction of new technologies that can demonstrably improve system performance.

  5. Radioactive Material Transportation Practices Manual

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2008-06-04

    This Manual establishes standard transportation practices for the Department of Energy, including National Nuclear Security Administration to use in planning and executing offsite shipments of radioactive materials and waste. The revision reflects ongoing collaboration of DOE and outside organizations on the transportation of radioactive material and waste. Supersedes DOE M 460.2-1.

  6. Charge-based transport and drug delivery into cartilage for localized treatment of degenerative joint diseases

    E-Print Network [OSTI]

    Bajpayee, Ambika Goel

    2015-01-01

    Traumatic joint injuries significantly increase synovial fluid levels of pro-inflammatory cytokines that can initiate cartilage degeneration leading to osteoarthritis (OA). Articular cartilage is a highly negatively charged, ...

  7. Tri-partite complex for axonal transport drug delivery achieves pharmacological effect

    E-Print Network [OSTI]

    Filler, Aaron G.; Whiteside, Garth T.; Bacon, Mark; Frederickson, Martyn; Howe, Franklyn A.; Rabinowitz, Miri D.; Sokoloff, Alan J.; Deacon, Terrence W.; Abell, Chris; Munglani, Raj; Griffiths, John R.; Bell, B. Anthony; Lever, Andrew M. L.

    2010-01-20

    be large when compared to the amount in the small volume of the nerve. In part, this reflects the fact that WGA adheres to muscle cell membranes [36] as well as being taken up by adsorptive endocytosis at nerve ter- mini. This also explains a depot effect...

  8. Coal Transportation Rate Sensitivity Analysis

    Reports and Publications (EIA)

    2005-01-01

    On December 21, 2004, the Surface Transportation Board (STB) requested that the Energy Information Administration (EIA) analyze the impact of changes in coal transportation rates on projected levels of electric power sector energy use and emissions. Specifically, the STB requested an analysis of changes in national and regional coal consumption and emissions resulting from adjustments in railroad transportation rates for Wyoming's Powder River Basin (PRB) coal using the National Energy Modeling System (NEMS). However, because NEMS operates at a relatively aggregate regional level and does not represent the costs of transporting coal over specific rail lines, this analysis reports on the impacts of interregional changes in transportation rates from those used in the Annual Energy Outlook 2005 (AEO2005) reference case.

  9. Energy Intensity Indicators: Transportation Energy Consumption

    Broader source: Energy.gov [DOE]

    This section contains an overview of the aggregate transportation sector, combining both passenger and freight segments of this sector. The specific energy intensity indicators for passenger and freight can be obtained from the links, passenger transportation, or freight transportation. For further detail within the transportation sector, download the appropriate Trend Data worksheet containing detailed data and graphics for specific transportation modes.

  10. Transportes em Revista.com Pas: Portugal

    E-Print Network [OSTI]

    Instituto de Sistemas e Robotica

    Transportes em Revista.com País: Portugal Period.: Diária Âmbito: Online Pag.: 1 de 2ID: 41904396 22-05-2012 Receba gr átis a Transportes Online | Assinar a Transportes em Revista | Fazer da TR a sua Transport Rodas de mudança Et si nos villes #12;Transportes em Revista.com País:

  11. February 2011 1906: Pure Food & Drugs Act regulated

    E-Print Network [OSTI]

    Arslan, Hüseyin

    February 2011 #12; 1906: Pure Food & Drugs Act ­ regulated adultered/misbranded food & drugs 1938: Food, Drugs, & Cosmetics Acts ­ required premarket review for safety 1962: FDCA Amendments ­ the birth for investigations of new drugs, including a requirement for informed consent #12; 21 CFR 312 Subpart A ­ general

  12. Uphill transport and the probabilistic transport model B. Ph. van Milligen

    E-Print Network [OSTI]

    van Milligen, Boudewijn

    Uphill transport and the probabilistic transport model B. Ph. van Milligen Asociacio´n EURATOM-CIEMAT

  13. Transport Survey 2008 (Staff and student)

    E-Print Network [OSTI]

    Burton, Geoffrey R.

    Transport Survey 2008 (Staff and student) April 2008 Ramon Arigoni Ortiz Wan-Jung Chou Department................................................................................................6 2. Transport use and travel behaviour......................................................................10 2.1. Modes of transport

  14. co2-transport | netl.doe.gov

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Transport Cost Model FENETL CO2 Transport Cost Model About the model: This model was developed to estimate the cost of transporting a user-specified mass rate of CO2 by pipeline...

  15. Anomalous transport through porous and fractured media

    E-Print Network [OSTI]

    Kang, Peter Kyungchul

    2014-01-01

    Anomalous transport, understood as the nonlinear scaling with time of the mean square displacement of transported particles, is observed in many physical processes, including contaminant transport through porous and fractured ...

  16. Transportes em Revista.com Pas: Portugal

    E-Print Network [OSTI]

    Instituto de Sistemas e Robotica

    Transportes em Revista.com País: Portugal Period.: Diária Âmbito: Online Pag.: 1 de 2ID: 44168021 10-10-2012 Receba gr átis a Transportes Online | Assinar a Transportes em Revista | Fazer da TR a sua

  17. Modeling oxaliplatin drug delivery to circadian rhythms in drug metabolism and host tolerance

    E-Print Network [OSTI]

    Clairambault, Jean

    period) time-scheduled regimens for cytotoxic drug delivery by intravenous infusion, a pharmacokinetic constant infusion of the same daily dose, when the biological time of peak infusion is correctly chosen. Furthermore, it is well adapted to using mathematical optimization methods of drug infusion flow, choosing

  18. Mar. Drugs 2015, 13, 3154-3181; doi:10.3390/md13053154 marine drugs

    E-Print Network [OSTI]

    Paré, Paul W.

    Mar. Drugs 2015, 13, 3154-3181; doi:10.3390/md13053154 marine drugs ISSN 1660-3397 www.mdpi.com/journal/marinedrugs Review Molecular Architecture and Biomedical Leads of Terpenes from Red Sea Marine Invertebrates Mohamed Costantino Received: 9 April 2015 / Accepted: 7 May 2015 / Published: 20 May 2015 Abstract: Marine

  19. Mar. Drugs 2013, 11, 4370-4389; doi:10.3390/md11114370 marine drugs

    E-Print Network [OSTI]

    Eirin Lopez, Jose Maria

    Mar. Drugs 2013, 11, 4370-4389; doi:10.3390/md11114370 marine drugs ISSN 1660-3397 www.mdpi.com/journal/marinedrugs Review Bivalve Omics: State of the Art and Potential Applications for the Biomonitoring of Harmful Marine of the marine ecosystem, constitute very valuable commercial resources in aquaculture, and have been widely used

  20. Transport Protocol Services (TAPS) Problem: more and more transport protocols available, with various features,

    E-Print Network [OSTI]

    Welzl, Michael

    Transport Protocol Services (TAPS) · Problem: more and more transport protocols that would not offer "TCP or UDP" but "transport services" ­ A transport system: transport-services@ifi.uio.no hXps://sympa.uio.no/ifi.uio.no/info/transport-services · Problem

  1. California’s Energy Future: Transportation Energy Use in California

    E-Print Network [OSTI]

    Yang, Christopher; Ogden, Joan M; Hwang, Roland; Sperling, Daniel

    2011-01-01

    truck activity in California. Transport Policy. Volume 16,in California Travel Demand Reductions Decreasing transportCalifornia, USA. Transportation Research, Part D: Transport

  2. Predicting Drug-Target Interaction for New Drugs Using Enhanced Similarity Measures and Super-Target Clustering1

    E-Print Network [OSTI]

    Chin, Francis Y.L.

    Predicting Drug-Target Interaction for New Drugs Using Enhanced Similarity Measures and Super.hku.hk, FYLC: chin@cs.hku.hk * To whom correspondence should be addressed. Abstract--Predicting drug-target interaction using computa- tional approaches is an important step in drug discovery and repositioning

  3. Section 21: Drug Discovery/Delivery Pharmacokinetic Considerations of Local Drug Delivery to the Inner Ear by

    E-Print Network [OSTI]

    Salt, Alec N.

    1 Section 21: Drug Discovery/Delivery Pharmacokinetic Considerations of Local Drug Delivery.Plontke@uni-tuebingen.de Although there is increasing interest in the local delivery of drugs to the inner ear by applying them to the round window (RW) membrane, most drug application protocols have been empirically- based. As a result

  4. Drug Research Assignment This assignment asks you choose a drug and learn how it works. This is NOT a writing

    E-Print Network [OSTI]

    Gates, Kent. S.

    CHEM 4170 Drug Research Assignment This assignment asks you choose a drug and learn how it works. This is NOT a writing assignment, this is a literature research project. The data for your drug will be presented below. Do not choose a drug that has been discussed in detail in Silverman's Book or in class. You may

  5. Essays on Urban Transportation and Transportation Energy Policy

    E-Print Network [OSTI]

    Kim, Chun Kon

    2008-01-01

    E?ects of Transportation Energy policy on Tra?c Crashes .e?ciency standards. Energy Policy, 33(3), 407–419. Blincoe,what’s necessary? Energy Policy, 34(9), 971–974. Bose, R.

  6. Environment-Assisted Quantum Transport

    E-Print Network [OSTI]

    Patrick Rebentrost; Masoud Mohseni; Ivan Kassal; Seth Lloyd; Alán Aspuru-Guzik

    2009-02-10

    Transport phenomena at the nanoscale are of interest due to the presence of both quantum and classical behavior. In this work, we demonstrate that quantum transport efficiency can be enhanced by a dynamical interplay of the system Hamiltonian with pure dephasing induced by a fluctuating environment. This is in contrast to fully coherent hopping that leads to localization in disordered systems, and to highly incoherent transfer that is eventually suppressed by the quantum Zeno effect. We study these phenomena in the Fenna-Matthews-Olson protein complex as a prototype for larger photosynthetic energy transfer systems. We also show that disordered binary tree structures exhibit enhanced transport in the presence of dephasing.

  7. Momentum Transport in Granular Flows

    E-Print Network [OSTI]

    Gregg Lois; Anael Lemaitre; Jean M. Carlson

    2006-02-10

    We investigate the error induced by only considering binary collisions in the momentum transport of hard-sphere granular materials, as is done in kinetic theories. In this process, we first present a general microscopic derivation of the momentum transport equation and compare it to the kinetic theory derivation, which relies on the binary collision assumption. These two derivations yield different microscopic expressions for the stress tensor, which we compare using simulations. This provides a quantitative bound on the regime where binary collisions dominate momentum transport and reveals that most realistic granular flows occur in the region of phase space where the binary collision assumption does not apply.

  8. Quantum transport through aromatic molecules

    SciTech Connect (OSTI)

    Ojeda, J. H.; Rey-González, R. R.; Laroze, D.

    2013-12-07

    In this paper, we study the electronic transport properties through aromatic molecules connected to two semi-infinite leads. The molecules are in different geometrical configurations including arrays. Using a nearest neighbor tight-binding approach, the transport properties are analyzed into a Green's function technique within a real-space renormalization scheme. We calculate the transmission probability and the Current-Voltage characteristics as a function of a molecule-leads coupling parameter. Our results show different transport regimes for these systems, exhibiting metal-semiconductor-insulator transitions and the possibility to employ them in molecular devices.

  9. Turbulence Induced Transport in Tokamaks

    SciTech Connect (OSTI)

    Caldas, I. L.; Marcus, F. A.; Heller, M. V. A. P.; Guimaraes-Filho, Z. O. [Instituto de Fisica, Universidade de Sao Paulo, Caixa Postal 66318, 05315-970, Sao Paulo, SP (Brazil); Batista, A. M. [Departamento de Matematica e Estatistica, Universidade Estadual de Ponta Grossa, Ponta Grossa, PR (Brazil); Viana, R. L.; Lopes, S. R. [Departamento de Fisica, Universidade Federal do Parana, 81531-990, Curitiba, PR (Brazil); Morrison, P. J.; Horton, W. [Department of Physics, University of Texas at Austin, Austin, Texas, 78712 (United States); Institute for Fusion Studies, The University of Texas at Austin, Austin, Texas, 78712 (United States)

    2006-12-04

    This report is concerned with plasma edge turbulence and its relation to anomalous particle transport in tokamaks. First, experimental evidence of turbulence driven particle transport and measurements of the gradients of the equilibrium profiles in the Brazilian tokamaks TBR and TCABR are presented. Next, diffusion in a two drift-wave system is discussed. In this nonintegrable system, particle transport is associated with the onset of chaotic orbits. Finally, numerical evidence suggesting that a nonlinear three-mode interaction could contribute to the intermittent plasma fluctuations observed in tokamaks is presented.

  10. UFD Storage and Transportation - Transportation Working Group Report

    SciTech Connect (OSTI)

    Maheras, Steven J.; Ross, Steven B.

    2011-08-01

    The Used Fuel Disposition (UFD) Transportation Task commenced in October 2010. As its first task, Pacific Northwest National Laboratory (PNNL) compiled a list of structures, systems, and components (SSCs) of transportation systems and their possible degradation mechanisms during extended storage. The list of SSCs and the associated degradation mechanisms [known as features, events, and processes (FEPs)] were based on the list of used nuclear fuel (UNF) storage system SSCs and degradation mechanisms developed by the UFD Storage Task (Hanson et al. 2011). Other sources of information surveyed to develop the list of SSCs and their degradation mechanisms included references such as Evaluation of the Technical Basis for Extended Dry Storage and Transportation of Used Nuclear Fuel (NWTRB 2010), Transportation, Aging and Disposal Canister System Performance Specification, Revision 1 (OCRWM 2008), Data Needs for Long-Term Storage of LWR Fuel (EPRI 1998), Technical Bases for Extended Dry Storage of Spent Nuclear Fuel (EPRI 2002), Used Fuel and High-Level Radioactive Waste Extended Storage Collaboration Program (EPRI 2010a), Industry Spent Fuel Storage Handbook (EPRI 2010b), and Transportation of Commercial Spent Nuclear Fuel, Issues Resolution (EPRI 2010c). SSCs include items such as the fuel, cladding, fuel baskets, neutron poisons, metal canisters, etc. Potential degradation mechanisms (FEPs) included mechanical, thermal, radiation and chemical stressors, such as fuel fragmentation, embrittlement of cladding by hydrogen, oxidation of cladding, metal fatigue, corrosion, etc. These degradation mechanisms are discussed in Section 2 of this report. The degradation mechanisms have been evaluated to determine if they would be influenced by extended storage or high burnup, the need for additional data, and their importance to transportation. These categories were used to identify the most significant transportation degradation mechanisms. As expected, for the most part, the transportation importance was mirrored by the importance assigned by the UFD Storage Task. A few of the more significant differences are described in Section 3 of this report

  11. Texarkana Urban Transportation Study 2035 Metropolitan Transportation Plan 

    E-Print Network [OSTI]

    Texarkana Metropolitan Planning Organization

    2009-10-01

    And Local Resource Agencies 1-7 Inclusion of Indian Tribes in the Transportation Process 1-8 2 SOCIO-ECONOMIC DATA 5 ROADS & BRIDGES Population Data 2-1 Road Performance 5-1 Housing Data 2... to increased motor fuels taxes or alternative revenue sources 4. Decaying infrastructure 5. Increasing demand for new infrastructure and access to alternative modes Starting with the Intermodal Surface Transportation Act of 1991 (ISTEA), the regulatory...

  12. Transportation Issues and Resolutions Compilation of Laboratory...

    Office of Environmental Management (EM)

    of cladding (embrittled, high burnup cladding, loads applied to cladding during transport), criticality analyses of failed UNF within transport packages, moderator exclusion...

  13. Anomalous energy transport across topological insulator superconductor...

    Office of Scientific and Technical Information (OSTI)

    Anomalous energy transport across topological insulator superconductor junctions Citation Details In-Document Search Title: Anomalous energy transport across topological insulator...

  14. Coal Gasification and Transportation Fuels Magazine

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Coal Gasification and Transportation Fuels Magazine Current Edition: Coal Gasification and Transportation Fuels Quarterly News, Vol.1, Issue 4 (July 2015) Archived Editions: Coal...

  15. Nearly 200 Attend National Transportation Stakeholders Forum...

    Office of Environmental Management (EM)

    national transportation coordination. BUFFALO, N.Y. - In his keynote address at the fourth-annual DOE National Transportation Stakeholders Forum (NTSF) meeting, EM Senior...

  16. Spring 2015 National Transportation Stakeholders Forum Meeting...

    Broader source: Energy.gov (indexed) [DOE]

    Spring 2015 National Transportation Stakeholders Forum Meeting, New Mexico The Spring 2015 meeting of the National Transportation Stakeholders Forum will be held on May 12-14, 2015...

  17. Transportation Equipment (2010 MECS) | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Equipment (2010 MECS) Transportation Equipment (2010 MECS) Manufacturing Energy and Carbon Footprint for Transportation Equipment Sector (NAICS 336) Energy use data source:...

  18. Transportation Safeguards & Security Test Bed (TSSTB) | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Transportation Safeguards and Security Test Bed May 30, 2013 The Transportation Safeguards and Security Test Bed consists of a test-bed vehicle and a monitoringlaboratorytraining...

  19. Standardization of Transport Properties Measurements: Internal...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Standardization of Transport Properties Measurements: Internal Energy Agency (IEA-AMT) Annex on Thermoelectric Standardization of Transport Properties Measurements: Internal Energy...

  20. We're All Transportation Planners

    E-Print Network [OSTI]

    Curry, Melanie

    2006-01-01

    transportation ment, has had some success in London’sLondon, offering our individual contribution to them. obser vations on current transportation

  1. Vehicle Technologies Office Merit Review 2015: Transportation...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Transportation Energy Data Book, Vehicle Technologies Market Report, and VT Fact of the Week Vehicle Technologies Office Merit Review 2015: Transportation Energy Data Book, Vehicle...

  2. Vehicle Technologies Office Merit Review 2014: Transportation...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Transportation Energy Data Book, Vehicle Technologies Market Report, and VT Fact of the Week Vehicle Technologies Office Merit Review 2014: Transportation Energy Data Book, Vehicle...

  3. Department of Transportation Pipeline and Hazardous Materials...

    Office of Environmental Management (EM)

    Conroy U S Department of Transportation - 1 - U.S. Department of Transportation Pipeline and Hazardous Materials Safety Administration Office of Hazardous Materials Safety...

  4. QER - Comment of Electric Drive Transportation Association |...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Drive Transportation Association QER - Comment of Electric Drive Transportation Association From: Genevieve Cullen gcullen@electricdrive.org Sent: Friday, October 10, 2014 11:58...

  5. EM Waste and Materials Disposition & Transportation

    Office of Environmental Management (EM)

    On Closure Success 1 EM Waste and Materials Disposition & Transportation National Transportation Stakeholders Forum Chicago, Illinois May 26, 2010 Frank Marcinowski Acting Chief...

  6. Assembly and electrical transport characterization of nanostructures...

    Office of Scientific and Technical Information (OSTI)

    Conference: Assembly and electrical transport characterization of nanostructures. Citation Details In-Document Search Title: Assembly and electrical transport characterization of...

  7. EM Waste and Materials Disposition & Transportation | Department...

    Office of Environmental Management (EM)

    & Transportation EM Waste and Materials Disposition & Transportation DOE's Radioactive Waste Management Priorities: Continue to manage waste inventories in a safe and compliant...

  8. Seamless Transport Policy: Institutional and Regulatory Aspects...

    Open Energy Info (EERE)

    Seamless Transport Policy: Institutional and Regulatory Aspects of Inter-Modal Coordination Jump to: navigation, search Tool Summary LAUNCH TOOL Name: Seamless Transport Policy:...

  9. Spring 2013 National Transportation Stakeholders Forum Meeting...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Stakeholders Forum Spring 2013 National Transportation Stakeholders Forum Meeting, New York Spring 2013 National Transportation Stakeholders Forum Meeting, New York Spring...

  10. Mitochondrial Transport and Function in Axon Degeneration

    E-Print Network [OSTI]

    O'Donnell, Kelley

    2013-01-01

    OF CALIFORNIA Los Angeles Mitochondrial Transport andTransport and Function in Axon Degeneration by Kelley O’Donnell Doctor of Philosophy in Neuroscience University of California,

  11. Transportation and Stationary Power Integration Workshop Agenda...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Agenda, October 27, 2008, Phoenix, Arizonia Transportation and Stationary Power Integration Workshop Agenda, October 27, 2008, Phoenix, Arizonia Agenda for the Transportation and...

  12. Transportation, Aging and Disposal Canister System Performance...

    Broader source: Energy.gov (indexed) [DOE]

    document provides specifications for selected system components of the Transportation, Aging and Disposal (TAD) canister-based system. Transportation, Aging and Disposal Canister...

  13. Macrobiotic Vertical Transport of Litter Derived Carbon

    E-Print Network [OSTI]

    Post, Wilfred M.

    Macrobiotic Vertical Transport of Litter Derived Carbon (Earthworm Phase) Mac Callaham Corey Babb in each treatment Sampling #12;Macrobiotic Vertical Transport of Litter Derived Carbon (millipede phase

  14. Oxygen Transport Ceramic Membranes

    SciTech Connect (OSTI)

    S. Bandopadhyay; N. Nagabhushana

    2003-08-07

    In the present quarter, experiments are presented on ceramic/metal interactions of Zirconia/ Ni-B-Si system and with a thin Ti coating deposited on zirconia surface. Existing facilities were modified for evaluation of environmental assisted slow crack growth and creep in flexural mode. Processing of perovskites of LSC, LSF and LSCF composition were continued for evaluation of mechanical properties as a function of environment. These studies in parallel to those on the LSFCO composition is expect to yield important information on questions such as the role of cation segregation and the stability of the perovskite structure on crack initiation vs. crack growth. Studies have been continued on the La{sub 1-x}Sr{sub x}FeO{sub 3-d} composition using neutron diffraction and TGA studies. A transition from p-type to n-type of conductor was observed at relative low pO{sub 2}, at which the majority carriers changed from the holes to electrons because of the valence state decreases in Fe due to the further loss of oxygen. Investigation on the thermodynamic properties of the membrane materials are continued to develop a complete model for the membrane transport. Data obtained at 850 C show that the stoichiometry in La{sub 0.2}Sr{sub 0.8}Fe{sub 0.8}Cr{sub 0.2}O{sub 3-x} vary from {approx}2.85 to 2.6 over the pressure range studied. From the stoichiometry a lower limit of 2.6 corresponding to the reduction of all Fe{sup 4+} to Fe{sup 3+} and no reduction of Cr{sup 3+} is expected.

  15. Seasonality in air transportation demand

    E-Print Network [OSTI]

    Reichard Megwinoff, H?tor Nicolas

    1988-01-01

    This thesis investigates the seasonality of demand in air transportation. It presents three methods for computing seasonal indices. One of these methods, the Periodic Average Method, is selected as the most appropriate for ...

  16. Washington: Integrated Transportation Programs & Coordinated...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    trip planner site that pulls together all regional transportation options into one portal. The project has already resulted in a reduction of 5.9 million vehicle miles traveled...

  17. Aerosol penetration through transport lines 

    E-Print Network [OSTI]

    Dileep, V.R.

    1996-01-01

    It is very important to minimize the losses in aerosol transport systems for the Continuous Air Monitors (CAM) to have a prompt and a meaningful alarm and the U.S. Environmental Protection Agency (EPA) also Currently mandates continuous emissions...

  18. Transportation scenarios for risk analysis.

    SciTech Connect (OSTI)

    Weiner, Ruth F.

    2010-09-01

    Transportation risk, like any risk, is defined by the risk triplet: what can happen (the scenario), how likely it is (the probability), and the resulting consequences. This paper evaluates the development of transportation scenarios, the associated probabilities, and the consequences. The most likely radioactive materials transportation scenario is routine, incident-free transportation, which has a probability indistinguishable from unity. Accident scenarios in radioactive materials transportation are of three different types: accidents in which there is no impact on the radioactive cargo, accidents in which some gamma shielding may be lost but there is no release of radioactive material, and accident in which radioactive material may potentially be released. Accident frequencies, obtainable from recorded data validated by the U.S. Department of Transportation, are considered equivalent to accident probabilities in this study. Probabilities of different types of accidents are conditional probabilities, conditional on an accident occurring, and are developed from event trees. Development of all of these probabilities and the associated highway and rail accident event trees are discussed in this paper.

  19. Apparatus for transporting hazardous materials

    DOE Patents [OSTI]

    Osterman, Robert A. (Canonsburg, PA); Cox, Robert (West Mifflin, PA)

    1992-01-01

    An apparatus and method are provided for selectively receiving, transporting, and releasing one or more radioactive or other hazardous samples for analysis on a differential thermal analysis (DTA) apparatus. The apparatus includes a portable sample transporting apparatus for storing and transporting the samples and includes a support assembly for supporting the transporting apparatus when a sample is transferred to the DTA apparatus. The transporting apparatus includes a storage member which includes a plurality of storage chambers arrayed circumferentially with respect to a central axis. An adjustable top door is located on the top side of the storage member, and the top door includes a channel capable of being selectively placed in registration with the respective storage chambers thereby permitting the samples to selectively enter the respective storage chambers. The top door, when closed, isolates the respective samples within the storage chambers. A plurality of spring-biased bottom doors are located on the bottom sides of the respective storage chambers. The bottom doors isolate the samples in the respective storage chambers when the bottom doors are in the closed position. The bottom doors permit the samples to leave the respective storage chambers from the bottom side when the respective bottom doors are in respective open positions. The bottom doors permit the samples to be loaded into the respective storage chambers after the analysis for storage and transport to a permanent storage location.

  20. Alcohol Transportation Fuels Demonstration Program

    SciTech Connect (OSTI)

    Kinoshita, C.M. (ed.)

    1990-01-01

    Hawaii has abundant natural energy resources, especially biomass, that could be used to produce alternative fuels for ground transportation and electricity. This report summarizes activities performed during 1988 to June 1991 in the first phase of the Alcohol Transportation Fuels Demonstration Program. The Alcohol Transportation Fuels Demonstration Program was funded initially by the Energy Division of the State of Hawaii's Department of Business, Economic Development and Tourism, and then by the US Department of Energy. This program was intended to support the transition to an altemative transportation fuel, methanol, by demonstrating the use of methanol fuel and methanol-fueled vehicles, and solving the problems associated with that fuel. Specific objectives include surveying renewable energy resources and ground transportation in Hawaii; installing a model methanol fueling station; demonstrating a methanol-fueled fleet of (spark-ignition engine) vehicles; evaluating modification strategies for methanol-fueled diesel engines and fuel additives; and investigating the transition to methanol fueling. All major objectives of Phase I were met (survey of local renewable resources and ground transportation, installation of methanol refueling station, fleet demonstration, diesel engine modification and additive evaluation, and dissemination of information on alternative fueling), and some specific problems (e.g., relating to methanol fuel contamination during handling and refueling) were identified and solved. Several key issues emerging from Phase I (e.g., methanol corrosion, flame luminosity, and methanol-transition technoeconomics) were recommended as topics for follow-on research in subsequent phases of this program.

  1. Uranium Transport Modeling

    SciTech Connect (OSTI)

    Bostick, William D.

    2008-01-15

    Uranium contamination is prevalent at many of the U.S. DOE facilities and at several civilian sites that have supported the nuclear fuel cycle. The potential off-site mobility of uranium depends on the partitioning of uranium between aqueous and solid (soil and sediment) phases. Hexavalent U (as uranyl, UO{sub 2}{sup 2+}) is relatively mobile, forming strong complexes with ubiquitous carbonate ion which renders it appreciably soluble even under mild reducing conditions. In the presence of carbonate, partition of uranyl to ferri-hydrate and select other mineral phases is usually maximum in the near-neutral pH range {approx} 5-8. The surface complexation reaction of uranyl with iron-containing minerals has been used as one means to model subsurface migration, used in conjunction with information on the site water chemistry and hydrology. Partitioning of uranium is often studied by short-term batch 'equilibrium' or long-term soil column testing ; MCLinc has performed both of these methodologies, with selection of method depending upon the requirements of the client or regulatory authority. Speciation of uranium in soil may be determined directly by instrumental techniques (e.g., x-ray photoelectron spectroscopy, XPS; x-ray diffraction, XRD; etc.) or by inference drawn from operational estimates. Often, the technique of choice for evaluating low-level radionuclide partitioning in soils and sediments is the sequential extraction approach. This methodology applies operationally-defined chemical treatments to selectively dissolve specific classes of macro-scale soil or sediment components. These methods recognize that total soil metal inventory is of limited use in understanding bioavailability or metal mobility, and that it is useful to estimate the amount of metal present in different solid-phase forms. Despite some drawbacks, the sequential extraction method can provide a valuable tool to distinguish among trace element fractions of different solubility related to mineral phases. Four case studies are presented: Water and Soil Characterization, Subsurface Stabilization of Uranium and other Toxic Metals, Reductive Precipitation (in situ bioremediation) of Uranium, and Physical Transport of Particle-bound Uranium by Erosion.

  2. Development and validation of personal monitoring methods for low levels of acrylonitrile in workplace atmosphere. I. Test atmosphere generation and solvent desorption methods

    SciTech Connect (OSTI)

    Melcher, R.G.; Borders, R.A.; Coyne, L.B.

    1986-03-01

    The purpose of this study was to optimize monitoring methods and to investigate new technology for the determination of low levels of acrylonitrile (0.05 to 5 ppm) in workplace atmospheres. In the first phase of the study, a dynamic atmosphere generation system was developed to produce low levels of acrylonitrile in simulated workplace atmospheres. Various potential sorbents were investigated in the second phase, and the candidate methods were compared in a laboratory validation study over a concentration range from 0.05 to 5 ppm acrylonitrile in the presence of potential interferences and under relative humidity conditions from 30% to 95% RH. A collection tube containing 600 mg Pittsburgh coconut base charcoal was found to be the optimum tube for sampling for a full 8 -hr shift. No breakthrough was observed over the concentrations and humidities tested. The recovery was 91.3% with a total relative precision of +/-21% over the test range, and the recovery was not affected by storage for up to five weeks.

  3. Alcohol and Other Drugs Education and Prevention

    E-Print Network [OSTI]

    . · The School's commitment to conducting a biennial review of its program. Employees, like students, are coveredAlcohol and Other Drugs Education and Prevention Policy Responsible Administrative Unit: Student.0 BACKGROUND AND PURPOSE The Colorado School of Mines is committed to: · Providing students educational

  4. RELATED ARTICLES Pricey Hepatitis C Drug Draws

    E-Print Network [OSTI]

    Kay, Mark A.

    Listen Tweet 28 RELATED ARTICLES Pricey Hepatitis C Drug Draws Criticism World Hepatitis Day Highlights Global Scourge, Hopes for Treatment News / Health Elimination of Chronic Hepatitis Feasible FILE A nurse vaccinates a child against hepatitis to prevent disease in Constitucion, Chile. Lisa Schlein July

  5. Poly(ethylene glycol)-conjugated multi-walled carbon nanotubes as an efficient drug carrier for overcoming multidrug resistance

    SciTech Connect (OSTI)

    Cheng Jinping [Department of Biology and Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon (Hong Kong); Meziani, Mohammed J.; Sun Yaping [Department of Chemistry and Laboratory for Emerging Materials and Technology, Clemson University, Clemson, SC 29634-0973 (United States); Cheng, Shuk Han, E-mail: bhcheng@cityu.edu.hk [Department of Biology and Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon (Hong Kong)

    2011-01-15

    The acquisition of multidrug resistance poses a serious problem in chemotherapy, and new types of transporters have been actively sought to overcome it. In the present study, poly(ethylene glycol)-conjugated (PEGylated) multi-walled carbon nanotubes (MWCNTs) were prepared and explored as drug carrier to overcome multidrug resistance. The prepared PEGylated MWCNTs penetrated into mammalian cells without damage plasma membrane, and its accumulation did not affect cell proliferation and cell cycle distribution. More importantly, PEGylated MWCNTs accumulated in the multidrug-resistant cancer cells as efficient as in the sensitive cancer cells. Intracellular translocation of PEGylated MWCNTs was visualized in both multidrug-resistant HepG2-DR cells and sensitive HepG2 cells, as judged by both fluorescent and transmission electron microscopy. PEGylated MWCNTs targeted cancer cells efficiently and multidrug-resistant cells failed to remove the intracellular MWCNTs. However, if used in combination with drugs without conjugation, PEGylated MWCNTs prompted drug efflux in MDR cells by stimulating the ATPase activity of P-glycoprotein. This study suggests that PEGylated MWCNTs can be developed as an efficient drug carrier to conjugate drugs for overcoming multidrug resistance in cancer chemotherapy.

  6. ENERGY TRANSPORT IN SEMICONDUCTOR DEVICES ANSGAR JUNGEL

    E-Print Network [OSTI]

    Jüngel, Ansgar

    ENERGY TRANSPORT IN SEMICONDUCTOR DEVICES ANSGAR J¨UNGEL Abstract. The modeling, analysis, and numerical approximation of energy-transport models for semiconductor devices is reviewed. The derivation-dependent energy-transport equations with physical transport coefficients. The discretization of the stationary

  7. Anomalous radial transport in tokamak edge plasma

    E-Print Network [OSTI]

    Bodi, Vasudeva Raghavendra Kowsik

    2010-01-01

    Transport in tokamak plasma . . . . . . . . . . . . . . .Numerical simulations of tokamak plasma . . . . . . . . .of blobs in tokamak edge plasmas . . . . . . . . . . . . . .

  8. Biofuel Feedstock Inter-Island Transportation

    E-Print Network [OSTI]

    of Honolulu Advertiser ISO Tank Container, courtesy of Hawaii Intermodal Tank Transport Petroleum products

  9. Public Transport and Sustainable Urbanism: Global Lesson

    E-Print Network [OSTI]

    Cervero, Robert

    2006-01-01

    Public Transport and Sustainable Urbanism: Global Lessonsviable and sustainable form of urbanism. Notes J. Kenworthy

  10. Pion capture and transport system for PRISM

    E-Print Network [OSTI]

    McDonald, Kirk

    solenoid cold mass Transport pions+muons in long 2T solenoid channelPion capture and transport system for PRISM M. Yoshida Osaka Univ. 2005/8/28 NuFACT06 at UCI #12 and transport system proton beam Phase rotator PRIME detector #12;Concepts of pion capture/transport system

  11. Enhancing Resource Sustainability by Transforming Urban and Suburban Transportation

    E-Print Network [OSTI]

    Delucchi, Mark

    2009-01-01

    Sustainable Transportation, Smart Growth, and New Urbanismsustainable transportation,” “smart growth,” and “new urbanism”

  12. Crystal structure of the Alcanivorax borkumensis YdaH transporter reveals an unusual topology

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Bolla, Jani Reddy; Su, Chih-Chia; Delmar, Jared A.; Radhakrishnan, Abhijith; Kumar, Nitin; Chou, Tsung-Han; Long, Feng; Rajashankar, Kanagalaghatta R.; Yu, Edward W.

    2015-04-20

    The potential of the folic acid biosynthesis pathway as a target for the development of antibiotics has been clinically validated. However, many pathogens have developed resistance to these antibiotics, prompting a re-evaluation of potential drug targets within the pathway. The ydaH gene of Alcanivorax borkumensis encodes an integral membrane protein of the AbgT family of transporters for which no structural information was available. Here we report the crystal structure of A. borkumensis YdaH, revealing a dimeric molecule with an architecture distinct from other families of transporters. YdaH is a bowl-shaped dimer with a solvent-filled basin extending from the cytoplasm tomore »halfway across the membrane bilayer. Each subunit of the transporter contains nine transmembrane helices and two hairpins that suggest a plausible pathway for substrate transport. Further analyses also suggest that YdaH could act as an antibiotic efflux pump and mediate bacterial resistance to sulfonamide antimetabolite drugs.« less

  13. Toledo Regional Economic PlanToledo Regional Economic Plan Transportation and LogisticsTransportation and Logistics

    E-Print Network [OSTI]

    Azad, Abdul-Majeed

    Toledo Regional Economic PlanToledo Regional Economic Plan Transportation and LogisticsTransportation and Logistics Industry SectorIndustry Sector Submitted by:Submitted by: Transportation and Logistics Working GroupTransportation and Logistics Working Group September 2009September 2009 #12;22 Transportation

  14. Luminal flow amplifies stent-based drug deposition in arterial

    E-Print Network [OSTI]

    Levine, Evan G.

    Background: Treatment of arterial bifurcation lesions using drug-eluting stents (DES) is now common clinical practice and yet the mechanisms governing drug distribution in these complex morphologies are incompletely ...

  15. Regression analysis of oncology drug licensing deal values

    E-Print Network [OSTI]

    Hawkins, Paul Allen

    2006-01-01

    This work is an attempt to explain wide variations in drug licensing deal value by using regression modeling to describe and predict the relationship between oncology drug deal characteristics and their licensing deal ...

  16. Takeda Advances Diabetes Drug Development at the ALS

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Takeda Advances Diabetes Drug Development at the ALS Takeda Advances Diabetes Drug Development at the ALS Print Tuesday, 19 May 2015 12:25 Type 2 diabetes mellitus (T2DM),...

  17. Optimization of preclinical profiling operations in drug discovery

    E-Print Network [OSTI]

    Heiney, John P. (John Patrick)

    2007-01-01

    In early-stage drug discovery, thousands of compounds must be tested using in vitro assays to determine their exposure and safety characteristics. This data is used to guide the selection of potential drug candidates and ...

  18. Measuring the effects of drugs on single cancer cell growth

    E-Print Network [OSTI]

    Weng, Yaochung

    2012-01-01

    Understanding the effectiveness of a drug therapy on halting disease progression is an essential aspect of cancer biology. Conventional assays that study cell behavior after a drug intervention report the average response ...

  19. Specific and general binding in arterial drug delivery

    E-Print Network [OSTI]

    Levin, Andrew D. (Andrew David), 1976-

    2005-01-01

    Drug-eluting stents have emerged as the most effective method for treating restenosis following percutaneous coronary interventions. This thesis investigates how drugs with similar physiochemical properties but different ...

  20. Amphiphilic linear-dendritic block copolymers for drug delivery

    E-Print Network [OSTI]

    Nguyen, Phuong, Ph. D. Massachusetts Institute of Technology

    2007-01-01

    Polymeric drug delivery systems have been widely used in the pharmaceutical industry. Such systems can solubilize and sequester hydrophobic drugs from degradation, thereby increasing circulation half-life and efficacy. ...

  1. Alignment strategies for drug product process development and manufacturing

    E-Print Network [OSTI]

    Garvin, Christopher John

    2012-01-01

    The transfer of information between the drug product development and manufacturing organizations is fundamental to drug product commercialization. This information is used to characterize the product-process interaction ...

  2. Overcoming Drug Resistance by Co-Targeting Marzieh Ayati1

    E-Print Network [OSTI]

    Wong, Limsoon

    , Statistics and Computer Science, University of Tehran, Tehran, Iran Abstract Removal or suppression of key to the drug. Communica- tion to the resistance machinery---e.g., efflux pumps and drug-modifying enzymes

  3. Topo II: An Enzyme Target for Antibacterial and Cancer Drugs

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Topo II: An Enzyme Target for Antibacterial and Cancer Drugs Topo II: An Enzyme Target for Antibacterial and Cancer Drugs Print Wednesday, 27 February 2008 00:00 The veil has...

  4. Microneedle delivery for improved efficacy of antiretroviral and antibiotic drugs

    E-Print Network [OSTI]

    Stauber, Zachary Jason

    2012-01-01

    Two classes of drugs, antiretrovirals and antibiotics, could benefit greatly from delivery through microneedles. Microneedles (MN) offer an increase in efficacy for these drugs by providing delivery to the lymphatic system ...

  5. Progress toward a Colon Targeting Nanoparticle Based Drug Delivery System 

    E-Print Network [OSTI]

    Yu, Xiao

    2012-07-16

    Hydrophobic drug paclitaxel nanoparticles (PAX NPs) and pH sensitive hydrogels were prepared in this study to build a colon targeting nanoparticle based drug delivery system for oral administration. Negative charged PAX NPs at the size of 110...

  6. Research Articles Combining Drug and Gene Similarity Measures

    E-Print Network [OSTI]

    Sharan, Roded

    of drug-drug and gene-gene similarity measures, combined with a logistic regression component to detection problems due to multiple gene and compound names. Additional attempts were based on reverse

  7. Methods of producing transportation fuel

    DOE Patents [OSTI]

    Nair, Vijay (Katy, TX); Roes, Augustinus Wilhelmus Maria (Houston, TX); Cherrillo, Ralph Anthony (Houston, TX); Bauldreay, Joanna M. (Chester, GB)

    2011-12-27

    Systems, methods, and heaters for treating a subsurface formation are described herein. At least one method for producing transportation fuel is described herein. The method for producing transportation fuel may include providing formation fluid having a boiling range distribution between -5.degree. C. and 350.degree. C. from a subsurface in situ heat treatment process to a subsurface treatment facility. A liquid stream may be separated from the formation fluid. The separated liquid stream may be hydrotreated and then distilled to produce a distilled stream having a boiling range distribution between 150.degree. C. and 350.degree. C. The distilled liquid stream may be combined with one or more additives to produce transportation fuel.

  8. No energy transport without discord

    E-Print Network [OSTI]

    Seth Lloyd; Vazrik Chiloyan; Yongjie Hu; Samuel Huberman; Zi-Wen Liu; Gang Chen

    2015-10-16

    Quantum systems can be correlated in ways that classical systems can not. A wide variety of non-classical forms of correlation exist: amongst the best known are entanglement and discord. Quantum correlations can be used to enhance measurement accuracy and energy transport. This paper shows that quantum correlations -- in the form of discord -- are mandatory for any energy transport. Without discord, energy transport cannot occur. Moreover, we show that the initial rate of heat transfer between two systems prepared at different temperatures is directly proportional to the rate of increase in diagonal/energetic discord between the systems. We measured the increase of energetic discord induced by nanoscale heat flow across an aluminum-sapphire interface. The rate of increase of discord is measured to be 4.28*10^24 bits m^{-2} K^{-1} s^{-1}.

  9. Cavity enhanced transport of excitons

    E-Print Network [OSTI]

    Johannes Schachenmayer; Claudiu Genes; Edoardo Tignone; Guido Pupillo

    2015-05-20

    We show that exciton-type transport in certain materials can be dramatically modified by their inclusion in an optical cavity: the modification of the electromagnetic vacuum mode structure introduced by the cavity leads to transport via delocalized polariton modes rather than through tunneling processes in the material itself. This can help overcome exponential suppression of transmission properties as a function of the system size in the case of disorder and other imperfections. We exemplify massive improvement of transmission for excitonic wave-packets through a cavity, as well as enhancement of steady-state exciton currents under incoherent pumping. These results may have implications for experiments of exciton transport in disordered organic materials. We propose that the basic phenomena can be observed in quantum simulators made of Rydberg atoms, cold molecules in optical lattices, as well as in experiments with trapped ions.

  10. Quantum transport in ultracold atoms

    E-Print Network [OSTI]

    Chih-Chun Chien; Sebastiano Peotta; Massimiliano Di Ventra

    2015-04-11

    Ultracold atoms confined by engineered magnetic or optical potentials are ideal systems for studying phenomena otherwise difficult to realize or probe in the solid state because their atomic interaction strength, number of species, density, and geometry can be independently controlled. This review focuses on quantum transport phenomena in atomic gases that mirror and oftentimes either better elucidate or show fundamental differences with those observed in mesoscopic and nanoscopic systems. We discuss significant progress in performing transport experiments in atomic gases, contrast similarities and differences between transport in cold atoms and in condensed matter systems, and survey inspiring theoretical predictions that are difficult to verify in conventional setups. These results further demonstrate the versatility offered by atomic systems in the study of nonequilibrium phenomena and their promise for novel applications.

  11. Aspirin and non-steroidal anti-inflammatory drugs for cancer prevention: an international consensus statement.

    E-Print Network [OSTI]

    2009-01-01

    nonsteroidal anti-in? ammatory drugs and risk of colorectalof nonsteroidal antiin? ammatory drugs: a pooled analysis ofsteroidal anti-in? ammatory drugs on colorectal adenomas:

  12. Anti-cancer drugs elicit re-expression of UDP-glucuronosyltransferases in melanoma cells.

    E-Print Network [OSTI]

    Dellinger, Ryan W; Matundan, Harry H; Ahmed, Amelia S; Duong, Priscilla H; Meyskens, Frank L Jr

    2012-01-01

    effect of valproic acid on drug and steroid glucuronidationglucuronosyltrans- ferases. Curr Drug Metab 1: 143–161. 10.aerodigestive tract tissues. Drug Metab Dispos 30: 397–403.

  13. Vapor Transport in Dry Soils

    SciTech Connect (OSTI)

    Gee, Glendon W.; Ward, Anderson L.

    2001-11-16

    Water-vapor movement in soils is a complex process, controlled by both diffusion and advection and influenced by pressure and thermal gradients acting across tortuous flow paths. Wide-ranging interest in water-vapor transport includes both theoretical and practical aspects. Just how pressure and thermal gradients enhance water-vapor flow is still not completely understood and subject to ongoing research. Practical aspects include dryland farming (surface mulching), water harvesting (aerial wells), fertilizer placement, and migration of contaminants at waste-sites. The following article describes the processes and practical applications of water-vapor transport, with emphasis on unsaturated (dry) soil systems.

  14. San Augustine School Transportation Building 

    E-Print Network [OSTI]

    Raiford Stripling Associates, Inc.; Stripling, Raiford L.

    2011-08-29

    ON FLUCTUATIONS IN TEE GEOSTROPHIC VOLUKE TRANSPORT OF TEE LAEBADOR CURBZlT A Thesis RIC&MB FOSTER EOHNSON Suhmitted to the Graduate College of Texas AA":i University in partial fulf~meni of ths rec;uirement for the degree of NA, '3TER... OF SCIENCE August 19'Pg H" Jor Sub?'ect: Hctsci clogy' ON FLUCTUAT10NS IN THE GEOSTROPHIC VOLUME TRANSPORT OF THE LAHRADOR CURRENT A Thesis RICHARD FOSTER JOHNSON Approved as to style and oontent by: onairman of Committee Member Head of Department...

  15. Transportation Resources | Advanced Photon Source

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorking With U.S.WeekProducts >Transportation currentlyTransportation

  16. Influence of Transport Variables on Isospin Transport Ratios

    E-Print Network [OSTI]

    D. D. S. Coupland; W. G. Lynch; M. B. Tsang; P. Danielewicz; Yingxun Zhang

    2011-07-19

    The symmetry energy in the nuclear equation of state affects many aspects of nuclear astrophysics, nuclear structure, and nuclear reactions. Recent constraints from heavy ion collisions, including isospin diffusion observables, have started to put constraints on the symmetry energy below nuclear saturation density, but these constraints depend on the employed transport model and input physics other than the symmetry energy. To understand these dependencies, we study the influence of the symmetry energy, isoscaler mean field compressibility and momentum dependence, in-medium nucleon-nucleon cross sections, and light cluster production on isospin diffusion within the pBUU transport code. In addition to the symmetry energy, several uncertain issues strongly affect isospin diffusion, most notably the cross sections and cluster production. In addition, there is a difference in the calculated isospin transport ratios, depending upon whether they are computed using the isospin asymmetry of either the residue or of all forward moving fragments. Measurements that compare the isospin transport ratios of these two quantities would help place constraints on the input physics, such as the density dependence of the symmetry energy.

  17. WVU Transportation Services http://transportation.wvu.edu/

    E-Print Network [OSTI]

    Mohaghegh, Shahab

    Route Options Greyhound · Daily Bus Service to Pittsburgh, PA, Washington, D.C., Clarksburg to Pittsburgh, PA and Washington, D.C. With Routes Through Canada Alternative Transportation Services http on the front of your permit. · Any permit area after 5:00 pm that is not 24 hour restricted Monday thru Friday

  18. Model-Based Dependability Analysis of Programmable Drug Infusion Pumps

    E-Print Network [OSTI]

    Sankaranarayanan, Sriram

    Model-Based Dependability Analysis of Programmable Drug Infusion Pumps Sriram Sankaranarayanan.lastname@colorado.edu Abstract. Infusion pumps are commonly used in home/hospital care to inject drugs into a patient a case-study involving an infusion pump used to manage pain through the infusion of analgesic drugs

  19. UNIVERSITY OF ABERDEEN POLICY ON DRUGS AND ALCOHOL

    E-Print Network [OSTI]

    Neri, Peter

    UNIVERSITY OF ABERDEEN POLICY ON DRUGS AND ALCOHOL 1 INTRODUCTION 1.1 The University of Aberdeen, and the introduction of a drugs and alcohol policy is intended to form an integral part of that approach. 1 and consistently. The University recognises that alcohol/drug dependency is an illness and will be treated

  20. An Algorithmic Framework for Predicting Side-Effects of Drugs

    E-Print Network [OSTI]

    Sharan, Roded

    An Algorithmic Framework for Predicting Side-Effects of Drugs Nir Atias and Roded Sharan Blavatnik,roded}@post.tau.ac.il Abstract. One of the critical stages in drug development is the iden- tification of potential side effects for promising drug leads. Large scale clinical experiments aimed at discovering such side effects are very

  1. Electric Vehicle Workplace Charging

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    or Twitter Attend local EV events Share your story Currently have 13 ChargePoint charging stations scattered throughout Vermont 2015 - 12 Freedom Stations & 10...

  2. Utilities and Workplace Charging

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Summit Mike Waters - Duke Energy November 18th, 2014 Duke Energy Electricity provider for over 7.2 million retail customers 6 states: NC, SC, FL, OH, IN, KY 104,000 sq....

  3. Workplace Charging Challenge

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    corporate leadership and innovation, demonstrating a willingness to adopt advanced technology. Sustainability Providing PEV charging can enhance corporate sustainability efforts,...

  4. Workplace Charging Challenge

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:Financing ToolInternationalReport FY2014 -Energy Costs byofMichelleWorkforceDepartmentRoad

  5. Electric Vehicle Workplace Charging

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based|DepartmentStatementofApril 25,EVtheEnergyPrepared forEnergy 10

  6. Trends in Workplace Charging

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious RankADVANCEDInstallers/ContractorsPhotovoltaicsState ofSavingsTransmissionin PEMFC27,Inc. ||Trends

  7. Utilities and Workplace Charging

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs Search USAJobs SearchWater-Saving Projects |Summit Mike Waters - Duke

  8. Optically generated ultrasound for enhanced drug delivery

    DOE Patents [OSTI]

    Visuri, Steven R. (Livermore, CA); Campbell, Heather L. (Baltimore, MD); Da Silva, Luiz (Danville, CA)

    2002-01-01

    High frequency acoustic waves, analogous to ultrasound, can enhance the delivery of therapeutic compounds into cells. The compounds delivered may be chemotherapeutic drugs, antibiotics, photodynamic drugs or gene therapies. The therapeutic compounds are administered systemically, or preferably locally to the targeted site. Local delivery can be accomplished through a needle, cannula, or through a variety of vascular catheters, depending on the location of routes of access. To enhance the systemic or local delivery of the therapeutic compounds, high frequency acoustic waves are generated locally near the target site, and preferably near the site of compound administration. The acoustic waves are produced via laser radiation interaction with an absorbing media and can be produced via thermoelastic expansion, thermodynamic vaporization, material ablation, or plasma formation. Acoustic waves have the effect of temporarily permeabilizing the membranes of local cells, increasing the diffusion of the therapeutic compound into the cells, allowing for decreased total body dosages, decreased side effects, and enabling new therapies.

  9. Media's Positive and Negative Frames in Reporting Celebrity Deaths From Illegal Drug Overdoses Versus Prescription Drug Overdoses

    E-Print Network [OSTI]

    Wood, Michelle

    2011-12-31

    This study compared the celebrity illegal drug overdose deaths of River Phoenix, Chris Farley, and Brad Renfro to the prescription drug overdose deaths of Anna Nicole Smith, Heath Ledger, and Brittany Murphy. This research ...

  10. Targeted drug delivery by novel polymer-drug conjugates containing linkers cleavable by disease-associated enzymes

    E-Print Network [OSTI]

    Chau, Ying

    2005-01-01

    We have conceptualized a new class of polymer-linker-drug conjugates to achieve targeted drug delivery for the systemic treatment of cancer and other inflammatory diseases. The physiochemical properties of the polymer allow ...

  11. Mathematical modeling and simulation of intravascular drug delivery from drug-eluting stents with biodegradable PLGA coating

    E-Print Network [OSTI]

    Zhu, Xiaoxiang, Ph. D. Massachusetts Institute of Technology

    2014-01-01

    Drug-eluting stents (DES) are commonly used in coronary angioplasty procedures. A DES elutes drug compounds from a thin polymeric coating into the surrounding coronary artery tissue to reduce in-stent restenosis (a significant ...

  12. Transportation of Hazardous Evidentiary Material.

    SciTech Connect (OSTI)

    Osborn, Douglas.

    2005-06-01

    This document describes the specimen and transportation containers currently available for use with hazardous and infectious materials. A detailed comparison of advantages, disadvantages, and costs of the different technologies is included. Short- and long-term recommendations are also provided.3 DraftDraftDraftExecutive SummaryThe Federal Bureau of Investigation's Hazardous Materials Response Unit currently has hazardous material transport containers for shipping 1-quart paint cans and small amounts of contaminated forensic evidence, but the containers may not be able to maintain their integrity under accident conditions or for some types of hazardous materials. This report provides guidance and recommendations on the availability of packages for the safe and secure transport of evidence consisting of or contaminated with hazardous chemicals or infectious materials. Only non-bulk containers were considered because these are appropriate for transport on small aircraft. This report will addresses packaging and transportation concerns for Hazardous Classes 3, 4, 5, 6, 8, and 9 materials. If the evidence is known or suspected of belonging to one of these Hazardous Classes, it must be packaged in accordance with the provisions of 49 CFR Part 173. The anthrax scare of several years ago, and less well publicized incidents involving unknown and uncharacterized substances, has required that suspicious substances be sent to appropriate analytical laboratories for analysis and characterization. Transportation of potentially hazardous or infectious material to an appropriate analytical laboratory requires transport containers that maintain both the biological and chemical integrity of the substance in question. As a rule, only relatively small quantities will be available for analysis. Appropriate transportation packaging is needed that will maintain the integrity of the substance, will not allow biological alteration, will not react chemically with the substance being shipped, and will otherwise maintain it as nearly as possible in its original condition.The recommendations provided are short-term solutions to the problems of shipping evidence, and have considered only currently commercially available containers. These containers may not be appropriate for all cases. Design, testing, and certification of new transportation containers would be necessary to provide a container appropriate for all cases.Table 1 provides a summary of the recommendations for each class of hazardous material.Table 1: Summary of RecommendationsContainerCost1-quart paint can with ArmlockTM seal ringLabelMaster(r)%242.90 eachHazard Class 3, 4, 5, 8, or 9 Small ContainersTC Hazardous Material Transport ContainerCurrently in Use4 DraftDraftDraftTable 1: Summary of Recommendations (continued)ContainerCost55-gallon open or closed-head steel drumsAll-Pak, Inc.%2458.28 - %2473.62 eachHazard Class 3, 4, 5, 8, or 9 Large Containers95-gallon poly overpack LabelMaster(r)%24194.50 each1-liter glass container with plastic coatingLabelMaster(r)%243.35 - %243.70 eachHazard Class 6 Division 6.1 Poisonous by Inhalation (PIH) Small ContainersTC Hazardous Material Transport ContainerCurrently in Use20 to 55-gallon PIH overpacksLabelMaster(r)%24142.50 - %24170.50 eachHazard Class 6 Division 6.1 Poisonous by Inhalation (PIH) Large Containers65 to 95-gallon poly overpacksLabelMaster(r)%24163.30 - %24194.50 each1-liter transparent containerCurrently in UseHazard Class 6 Division 6.2 Infectious Material Small ContainersInfectious Substance ShipperSource Packaging of NE, Inc.%24336.00 eachNone Commercially AvailableN/AHazard Class 6 Division 6.2 Infectious Material Large ContainersNone Commercially Available N/A5

  13. Transporting Information and Energy Simultaneously

    E-Print Network [OSTI]

    Goyal, Vivek K

    Transporting Information and Energy Simultaneously Lav R. Varshney Laboratory for Information--The fundamental tradeoff between the rates at which energy and reliable information can be transmitted over received energy. A capacity-energy function is defined and a coding theorem is given. The capacity-energy

  14. Memory effects in turbulent transport

    E-Print Network [OSTI]

    Alexander Hubbard; Axel Brandenburg

    2009-11-13

    In the mean-field theory of magnetic fields, turbulent transport, i.e. the turbulent electromotive force, is described by a combination of the alpha effect and turbulent magnetic diffusion, which are usually assumed to be proportional respectively to the mean field and its spatial derivatives. For a passive scalar there is just turbulent diffusion, where the mean flux of concentration depends on the gradient of the mean concentration. However, these proportionalities are approximations that are valid only if the mean field or the mean concentration vary slowly in time. Examples are presented where turbulent transport possesses memory, i.e. where it depends crucially on the past history of the mean field. Such effects are captured by replacing turbulent transport coefficients with time integral kernels, resulting in transport coefficients that depend effectively on the frequency or the growth rate of the mean field itself. In this paper we perform numerical experiments to find the characteristic timescale (or memory length) of this effect as well as simple analytical models of the integral kernels in the case of passive scalar concentrations and kinematic dynamos. The integral kernels can then be used to find self-consistent growth or decay rates of the mean fields. In mean-field dynamos the growth rates and cycle periods based on steady state values of alpha effect and turbulent diffusivity can be quite different from the actual values.

  15. Electrofuels: Versatile Transportation Energy Solutions

    SciTech Connect (OSTI)

    None

    2010-07-01

    Electrofuels Project: ARPA-E’s Electrofuels Project is using microorganisms to create liquid transportation fuels in a new and different way that could be up to 10 times more energy efficient than current biofuel production methods. ARPA-E is the only U.S. government agency currently funding research on Electrofuels.

  16. Sustainable Transportation Energy Pathways Research

    E-Print Network [OSTI]

    Handy, Susan L.

    FUEL/VEHICLE PATHWAYS (ROAD VEH.) #12;Transport Fuels Today (94% petro-based, 2% biofuel) IEA Energy Technology Perspectives (2010) #12;IEA ETP 2012: THREE ENERGY SCENARIOS 6 DS (Current Policies), 4 DS, 2DS Source: IEA Energy Technology Perspectives (2012) #12;MEETING 2050 GHG REDUCTION GOALS => FUEL MIX

  17. Engineering transport by concatenated maps

    E-Print Network [OSTI]

    T. Schell; M. Sadgrove; K. Nakagawa; S. Wimberger

    2013-10-22

    We present a generalized kick rotor model in which the phase of the kick can vary from kick to kick. This additional freedom allows one to control the transport in phase space. For a specific choice of kick-to-kick phases, we predict novel forms of accelerator modes which are potentially of high relevance for future experimental studies.

  18. Saturation and linear transport equation

    E-Print Network [OSTI]

    Krzysztof Kutak

    2009-04-29

    We show that the GBW saturation model provides an exact solution to the one dimensional linear transport equation. We also show that it is motivated by the BK equation considered in the saturated regime when the diffusion and the splitting term in the diffusive approximation are balanced by the nonlinear term.

  19. LouisianaTransportation Research Center

    E-Print Network [OSTI]

    Stephens, Jacqueline

    Transportation and Development and Louisiana State University A.Wave propagation of the pile-energy is generated as the pile and provides technology assistance, engineering training and continuing education, technology transfer) and at the pile tip (5)]; C.Wave p

  20. AutoDrug: fully automated macromolecular crystallography workflows for fragment-based drug discovery

    SciTech Connect (OSTI)

    Tsai, Yingssu; McPhillips, Scott E.; González, Ana; McPhillips, Timothy M.; Zinn, Daniel; Cohen, Aina E.; Feese, Michael D.; Bushnell, David; Tiefenbrunn, Theresa; Stout, C. David; Ludaescher, Bertram; Hedman, Britt; Hodgson, Keith O.; Soltis, S. Michael

    2013-05-01

    New software has been developed for automating the experimental and data-processing stages of fragment-based drug discovery at a macromolecular crystallography beamline. A new workflow-automation framework orchestrates beamline-control and data-analysis software while organizing results from multiple samples. AutoDrug is software based upon the scientific workflow paradigm that integrates the Stanford Synchrotron Radiation Lightsource macromolecular crystallography beamlines and third-party processing software to automate the crystallography steps of the fragment-based drug-discovery process. AutoDrug screens a cassette of fragment-soaked crystals, selects crystals for data collection based on screening results and user-specified criteria and determines optimal data-collection strategies. It then collects and processes diffraction data, performs molecular replacement using provided models and detects electron density that is likely to arise from bound fragments. All processes are fully automated, i.e. are performed without user interaction or supervision. Samples can be screened in groups corresponding to particular proteins, crystal forms and/or soaking conditions. A single AutoDrug run is only limited by the capacity of the sample-storage dewar at the beamline: currently 288 samples. AutoDrug was developed in conjunction with RestFlow, a new scientific workflow-automation framework. RestFlow simplifies the design of AutoDrug by managing the flow of data and the organization of results and by orchestrating the execution of computational pipeline steps. It also simplifies the execution and interaction of third-party programs and the beamline-control system. Modeling AutoDrug as a scientific workflow enables multiple variants that meet the requirements of different user groups to be developed and supported. A workflow tailored to mimic the crystallography stages comprising the drug-discovery pipeline of CoCrystal Discovery Inc. has been deployed and successfully demonstrated. This workflow was run once on the same 96 samples that the group had examined manually and the workflow cycled successfully through all of the samples, collected data from the same samples that were selected manually and located the same peaks of unmodeled density in the resulting difference Fourier maps.