National Library of Energy BETA

Sample records for topics pathways analysis

  1. Global Pathways Analysis Tool (GPAT)

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Pathways Analysis Tool (GPAT) (Sandia National Laboratories) Objectives Calculate least-cost pathways for hydrogen supply for eight participating countries: France, Germany, ...

  2. Additional EIPC Study Analysis: Interim Report on High Priority Topics

    SciTech Connect (OSTI)

    Hadley, Stanton W

    2013-11-01

    Between 2010 and 2012 the Eastern Interconnection Planning Collaborative (EIPC) conducted a major long-term resource and transmission study of the Eastern Interconnection (EI). With guidance from a Stakeholder Steering Committee (SSC) that included representatives from the Eastern Interconnection States Planning Council (EISPC) among others, the project was conducted in two phases. Phase 1 involved a long-term capacity expansion analysis that involved creation of eight major futures plus 72 sensitivities. Three scenarios were selected for more extensive transmission- focused evaluation in Phase 2. Five power flow analyses, nine production cost model runs (including six sensitivities), and three capital cost estimations were developed during this second phase. The results from Phase 1 and 2 provided a wealth of data that could be examined further to address energy-related questions. A list of 13 topics was developed for further analysis; this paper discusses the first five.

  3. Technoeconomic Boundary Analysis of Biological Pathways to Hydrogen...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Technoeconomic Boundary Analysis of Biological Pathways to Hydrogen Production Technoeconomic Boundary Analysis of Biological Pathways to Hydrogen Production Report documenting the ...

  4. Techno-Economic Boundary Analysis of Biological Pathways to Hydrogen...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Techno-Economic Boundary Analysis of Biological Pathways to Hydrogen Production (2009) Techno-Economic Boundary Analysis of Biological Pathways to Hydrogen Production (2009) ...

  5. Supply Chain Sustainability Analysis of Three Biofuel Pathways...

    Office of Scientific and Technical Information (OSTI)

    Supply Chain Sustainability Analysis of Three Biofuel Pathways Citation Details In-Document Search Title: Supply Chain Sustainability Analysis of Three Biofuel Pathways The ...

  6. Final report on the Pathway Analysis Task

    SciTech Connect (OSTI)

    Whicker, F.W.; Kirchner, T.B.

    1993-04-01

    The Pathway Analysis Task constituted one of several multi-laboratory efforts to estimate radiation doses to people, considering all important pathways of exposure, from the testing of nuclear devices at the Nevada Test Site (NTS). The primary goal of the Pathway Analysis Task was to predict radionuclide ingestion by residents of Utah, Nevada, and portions of seven other adjoining western states following radioactive fallout deposition from individual events at the NTS. This report provides comprehensive documentation of the activities and accomplishments of Colorado State University`s Pathway Analysis Task during the entire period of support (1979--91). The history of the project will be summarized, indicating the principal dates and milestones, personnel involved, subcontractors, and budget information. Accomplishments, both primary and auxiliary, will be summarized with general results rather than technical details being emphasized. This will also serve as a guide to the reports and open literature publications produced, where the methodological details and specific results are documented. Selected examples of results on internal dose estimates are provided in this report because the data have not been published elsewhere.

  7. Deduction and Analysis of the Interacting Stress Response Pathways...

    Office of Scientific and Technical Information (OSTI)

    Deduction and Analysis of the Interacting Stress Response Pathways of MetalRadionuclide-reducing Bacteria Citation Details In-Document Search Title: Deduction and Analysis of the ...

  8. Technoeconomic Boundary Analysis of Biological Pathways to Hydrogen

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Production | Department of Energy Boundary Analysis of Biological Pathways to Hydrogen Production Technoeconomic Boundary Analysis of Biological Pathways to Hydrogen Production Report documenting the biological and engineering characteristics of five algal and bacterial hydrogen production systems selected by DOE and NREL for evaluation. Technoeconomic Boundary Analysis of Biological Pathways to Hydrogen Production (3.63 MB) More Documents & Publications Techno-Economic Boundary Analysis

  9. Hydrogen Supply: Cost Estimate for Hydrogen Pathways-Scoping Analysis.

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    January 22, 2002-July 22, 2002 | Department of Energy Supply: Cost Estimate for Hydrogen Pathways-Scoping Analysis. January 22, 2002-July 22, 2002 Hydrogen Supply: Cost Estimate for Hydrogen Pathways-Scoping Analysis. January 22, 2002-July 22, 2002 A report showing a comparative scooping economic analysis of 19 pathways for producing, handling, distributing, and dispensing hydrogen for fuel cell vehicle applications. 32525.pdf (1.48 MB) More Documents & Publications Analysis of a Cluster

  10. CRITICAL RADIONUCLIDE AND PATHWAY ANALYSIS FOR THE SAVANNAH RIVER SITE

    SciTech Connect (OSTI)

    Jannik, T.

    2011-08-30

    This report is an update to the analysis, Assessment of SRS Radiological Liquid and Airborne Contaminants and Pathways, that was performed in 1997. An electronic version of this large original report is included in the attached CD to this report. During the operational history (1954 to the present) of the Savannah River Site (SRS), many different radionuclides have been released to the environment from the various production facilities. However, as will be shown by this updated radiological critical contaminant/critical pathway analysis, only a small number of the released radionuclides have been significant contributors to potential doses and risks to offsite people. The analysis covers radiological releases to the atmosphere and to surface waters, the principal media that carry contaminants offsite. These releases potentially result in exposure to offsite people. The groundwater monitoring performed at the site shows that an estimated 5 to 10% of SRS has been contaminated by radionuclides, no evidence exists from the extensive monitoring performed that groundwater contaminated with these constituents has migrated off the site (SRS 2011). Therefore, with the notable exception of radiological source terms originating from shallow surface water migration into site streams, onsite groundwater was not considered as a potential exposure pathway to offsite people. In addition, in response to the Department of Energy's (DOE) Order 435.1, several Performance Assessments (WSRC 2008; LWO 2009; SRR 2010; SRR 2011) and a Comprehensive SRS Composite Analysis (SRNO 2010) have recently been completed at SRS. The critical radionuclides and pathways identified in these extensive reports are discussed and, where applicable, included in this analysis.

  11. Bottom-Up Energy Analysis System (BUENAS) | Open Energy Information

    Open Energy Info (EERE)

    Lawrence Berkeley National Laboratory Sector: Energy Focus Area: Buildings, Energy Efficiency Topics: Baseline projection, - Macroeconomic, Pathways analysis Resource Type:...

  12. Technoeconomic Boundary Analysis of Biological Pathways to Hydrogen Production

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Subcontract Report NREL/SR-560-46674 September 2009 Technoeconomic Boundary Analysis of Biological Pathways to Hydrogen Production March 27, 2008 - August 31, 2009 B.D. James, G.N. Baum, J. Perez, and K.N. Baum Directed Technologies, Inc. Arlington, Virginia National Renewable Energy Laboratory 1617 Cole Boulevard, Golden, Colorado 80401-3393 303-275-3000 * www.nrel.gov NREL is a national laboratory of the U.S. Department of Energy Office of Energy Efficiency and Renewable Energy Operated by the

  13. Decision Analysis Tool to Compare Energy Pathways for Transportation

    SciTech Connect (OSTI)

    Bloyd, Cary N.

    2010-06-30

    With the goals of reducing greenhouse gas emissions, oil imports, and energy costs, a wide variety of automotive technologies are proposed to replace the traditional gasoline-powered internal combustion engine (g-ICE). Biomass is seen as an important domestic energy feedstock, and there are multiple pathways in which it can be linked to the transport sector. Contenders include the use of cellulosic ethanol from biomass to replace gasoline or the use of a biomass-fueled combined cycle electrical power generation facility in conjunction plug-in hybrid electric vehicles (PHEVs). This paper reviews a project that is developing a scenario decision analysis tool to assist policy makers, program managers, and others to obtain a better understanding of these uncertain possibilities and how they may interact over time.

  14. Pathway analysis for a contaminated landfill in Middlesex, New Jersey

    SciTech Connect (OSTI)

    Yu, C.; Merry-Libby, P.; Yang, J.Y.

    1985-01-01

    Under the Formerly Utilized Sites Remedial Action Program, the US Department of Energy began excavating contaminated materials from the Middlesex Municipal landfill in 1984. A total of 16,000 mT of landfill materials covering a 0.2-ha area was excavated, of which 11,000 mT was contaminated and has been transported to the nearby sampling plant site for interim storage. Based on the pathway analysis for the onsite and near-site resident scenarios, the radiation dose rates and radionuclide concentrations in groundwater would be below the regulatory requirements for both the short-term and long-term scenarios. Hence, the potential health risks to maximally exposed individuals due to radioactive releases from the Middlesex landfill would be insignificant.

  15. Supply Chain Sustainability Analysis of Three Biofuel Pathways

    SciTech Connect (OSTI)

    Jacob J. Jacobson; Erin Searcy; Kara Cafferty; Jennifer B. Dunn; Michael Johnson; Zhichao Wang; Michael Wang; Mary Biddy; Abhijit Dutta; Daniel Inman; Eric Tan; Sue Jones; Lesley Snowden-Swan

    2013-11-01

    The Department of Energy’s (DOE) Bioenergy Technologies Office (BETO) collaborates with industrial, agricultural, and non-profit partners to develop and deploy biofuels and other biologically-derived products. As part of this effort, BETO and its national laboratory teams conduct in-depth techno-economic assessments (TEA) of technologies to produce biofuels as part state of technology (SOT) analyses. An SOT assesses progress within and across relevant technology areas based on actual experimental results relative to technical targets and cost goals from design cases and includes technical, economic, and environmental criteria as available. Overall assessments of biofuel pathways begin with feedstock production and the logistics of transporting the feedstock from the farm or plantation to the conversion facility or biorefinery. The conversion process itself is modeled in detail as part of the SOT analysis. The teams then develop an estimate of the biofuel minimum selling price (MSP) and assess the cost competitiveness of the biofuel with conventional fuels such as gasoline.

  16. Topic Committee

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    RAP Work Plan Topics Page 1 of 3 Topic Committee Potential FY 2016 Action/Product Context (from FY 2016 HAB Work Plan) 6-Month Status (IM, Committee, Advice, Deferred, No Action) 1. 100 Area retrieval process, K Basin RAP Project update (May not be ready until 2017 for an update; work ready in 2018 per milestone)  Attended tour in October 2015, including visit to MO-500/Sludge Annex facility 2. 100 D/H Proposed Plan RAP Project update Cleanup of soils and groundwater at D/H. Are the proposed

  17. 2013-01 "Action in Analysis of Disposal Pathways for Disposition of 33

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Shafts" | Department of Energy 1 "Action in Analysis of Disposal Pathways for Disposition of 33 Shafts" 2013-01 "Action in Analysis of Disposal Pathways for Disposition of 33 Shafts" The intent of this Recommendation 2013-01 remains the same as 2010-01, namely to discourage inaction in addressing the permanent disposition of the 33 shafts. Rec 2013-01 - January 30, 2013 (204.48

  18. Relevance of biotic pathways to the long-term regulation of nuclear waste disposal. Topical report on reference eastern humid low-level sites

    SciTech Connect (OSTI)

    McKenzie, D.H.; Cadwell, L.L.; Eberhardt, L.E.; Kennedy, W.E. Jr.; Peloquin, R.A.; Simmons, M.A.

    1983-01-01

    The purpose of the work reported here was to develop an order-of-magnitude estimate for the potential dose to man resulting from biotic transport mechanisms at a humid reference low-level waste site in the eastern US. A description of the reference site is presented that includes the waste inventories, site characteristics and biological communites. Parameter values for biotic transport processes are based on data reported in current literature. Transport and exposure scenarios are developed for assessing biotic transport during 500 years following site closure. Calculations of radionuclide decay and waste container decomposition are made to estimate the quantities available for biotic transport. Doses to man are calculated for the biological transport of radionucludes at the reference site after loss of institutional control. These dose estimates are compared to dose estimates we calculated for the intruder-agricultural scenarios reported in the DEIS for 10 CFR 61 (NRC). Dose to man estimates as a result of cumulative biotic transport are calculated to be of the same order-of-magnitude as the dose resulting from the more commonly evaluated human intrusion scenario. The reported lack of potential importance of biotic transport at low-level waste sites in earlier assessment studies is not confirmed by findings presented in this report. Through biotic transport, radionuclides can be moved to locations where they can enter exposure pathways to man.

  19. Relevance of biotic pathways to the long-term regulation of nuclear-waste disposal. Topical report on reference western arid low-level sites

    SciTech Connect (OSTI)

    McKenzie, D.H.; Cadwell, L.L.; Eberhardt, L.E.; Kennedy, W.E. Jr.; Peloquin, R.A.; Simmons, M.A.

    1982-10-01

    The purpose of the work reported here was to develop an order of magnitude estimate for the potential dose to man resulting from biotic transport mechanisms at a reference western arid low-level waste site. A description of the reference site is presented that includes the waste inventories, site characteristics and biological communities. Parameter values for biotic transport processes are based on data reported in current literature. Transport and exposure scenarios are developed for assessing biotic transport during 100 years following site closure. Calculations of radionuclide decay and waste container decomposition are made to estimate the quantities available for biotic transport. Dose to a man occupying the reference site following the 100 years of biotic transport are calculated. These dose estimates are compared to dose estimates for the intruder-agricultural scenario reported in the DEIS for 10 CFR 61 (NRC). Dose to man estimates as a result of biotic transport are estimated to be of the same order of magnitude as the dose resulting from the more commonly evaluated human intrusion scenario. The reported lack of potential importance of biotic transport at low-level waste sites in earlier assessment studies is not confirmed by the findings presented in this report. These results indicate that biotic transport has the potential to influence low-level waste site performance. Through biotic transport, radionuclides may be moved to locations where they can enter exposure pathways to man.

  20. Economic evaluation and market analysis for natural gas utilization. Topical report

    SciTech Connect (OSTI)

    Hackworth, J.H.; Koch, R.W.; Rezaiyan, A.J.

    1995-04-01

    During the past decade, the U.S. has experienced a surplus gas supply. Future prospects are brightening because of increased estimates of the potential size of undiscovered gas reserves. At the same time, U.S. oil reserves and production have steadily declined, while oil imports have steadily increased. Reducing volume growth of crude oil imports was a key objective of the Energy Policy Act of 1992. Natural gas could be an important alternative energy source to liquid products derived from crude oil to help meet market demand. The purpose of this study was to (1) analyze three energy markets to determine whether greater use could be made of natural gas or its derivatives and (2) determine whether those products could be provided on an economically competitive basis. The following three markets were targeted for possible increases in gas use: transportation fuels, power generation, and chemical feedstock. Gas-derived products that could potentially compete in these three markets were identified, and the economics of the processes for producing those products were evaluated. The processes considered covered the range from commercial to those in early stages of process development. The analysis also evaluated the use of both high-quality natural gas and lower-quality gases containing CO{sub 2} and N{sub 2} levels above normal pipeline quality standards.

  1. Topical safety analysis report for the transportation of the NUHOMS{reg_sign} dry shielded canister. Volume 1

    SciTech Connect (OSTI)

    1993-08-01

    This Topical Safety Analysis Report (SAR) describes the design and the generic transportation licensing basis for utilizing the NUTECH HORIZONTAL MODULAR STORAGE (NUHOMS{reg_sign}) system dry shielded canister (DSC) containing twenty-four pressurized water reactor (PWR) spent fuel assemblies (SFA) in conjunction with a conceptually designed Transportation Cask. This SAR documents the design qualification of the NUHOMS{reg_sign} DSC as an integral part of a 10CFR71 Fissile Material Class III, Type B(M) Transportation Package. The package consists of the canister and a conceptual transportation cask (NUHOMS{reg_sign} Transportation Cask) with impact limiters. Engineering analysis is performed for the canister to confirm that the existing canister design complies with 10CFR71 transportation requirements. Evaluations and/or analyses is performed for criticality safety, shielding, structural, and thermal performance. Detailed engineering analysis for the transportation cask will be submitted in a future SAR requesting 10CFR71 certification of the complete waste package. Transportation operational considerations describe various operational aspects of the canister/transportation cask system. operational sequences are developed for canister transfer from storage to the transportation cask and interfaces with the cask auxiliary equipment for on- and off-site transport.

  2. Decision Analysis Tool to Compare Energy Pathways for Transportation

    SciTech Connect (OSTI)

    Bloyd, Cary N.; Stork, Kevin

    2011-02-01

    With the goals of reducing greenhouse gas emissions, oil imports, and energy costs, a wide variety of automotive technologies are proposed to replace the traditional gasoline-powered internal combustion engine (g-ICE). A prototype model, Analytica Transportation Energy Analysis Model (ATEAM), has been developed using the Analytica decision modeling environment, visualizing the structure as a hierarchy of influence diagrams. The report summarized the FY2010 ATEAM accomplishments.

  3. Integrated analysis of hydrogen passenger vehicle transportation pathways

    SciTech Connect (OSTI)

    Thomas, C.E.; James, B.D.; Lomax, F.D. Jr.; Kuhn, I.F. Jr.

    1998-08-01

    Hydrogen-powered fuel cell vehicles will reduce local air pollution, greenhouse gas emissions and oil imports. Other alternative vehicles such as gasoline- or methanol-powered fuel cell vehicles, natural gas vehicles and various hybrid electric vehicles with internal combustion engines may also provide significant environmental and national security advantages. This report summarizes a two-year project to compare the direct hydrogen fuel cell vehicle with other alternatives in terms of estimated cost and estimated societal benefits, all relative to a conventional gasoline-powered internal combustion engine vehicle. The cost estimates used in this study involve ground-up, detailed analysis of the major components of a fuel cell vehicle system, assuming mass production in automotive quantities. The authors have also estimated the cost of both gasoline and methanol onboard fuel processors, as well as the cost of stationary hydrogen fueling system components including steam methane reformers, electrolyzers, compressors and stationary storage systems. Sixteen different vehicle types are compared with respect to mass production cost, local air pollution and greenhouse gas emissions.

  4. Transcriptomic analysis in the developing zebrafish embryo after compound exposure: Individual gene expression and pathway regulation

    SciTech Connect (OSTI)

    Hermsen, Sanne A.B.; Pronk, Tessa E.; Brandhof, Evert-Jan van den; Ven, Leo T.M. van der; Piersma, Aldert H.

    2013-10-01

    The zebrafish embryotoxicity test is a promising alternative assay for developmental toxicity. Classically, morphological assessment of the embryos is applied to evaluate the effects of compound exposure. However, by applying differential gene expression analysis the sensitivity and predictability of the test may be increased. For defining gene expression signatures of developmental toxicity, we explored the possibility of using gene expression signatures of compound exposures based on commonly expressed individual genes as well as based on regulated gene pathways. Four developmental toxic compounds were tested in concentration-response design, caffeine, carbamazepine, retinoic acid and valproic acid, and two non-embryotoxic compounds, D-mannitol and saccharin, were included. With transcriptomic analyses we were able to identify commonly expressed genes, which were mostly development related, after exposure to the embryotoxicants. We also identified gene pathways regulated by the embryotoxicants, suggestive of their modes of action. Furthermore, whereas pathways may be regulated by all compounds, individual gene expression within these pathways can differ for each compound. Overall, the present study suggests that the use of individual gene expression signatures as well as pathway regulation may be useful starting points for defining gene biomarkers for predicting embryotoxicity. - Highlights: • The zebrafish embryotoxicity test in combination with transcriptomics was used. • We explored two approaches of defining gene biomarkers for developmental toxicity. • Four compounds in concentration-response design were tested. • We identified commonly expressed individual genes as well as regulated gene pathways. • Both approaches seem suitable starting points for defining gene biomarkers.

  5. Probabilistic approach to identify sensitive parameter distributions in multimedia pathway analysis.

    SciTech Connect (OSTI)

    Kamboj, S.; Gnanapragasam, E.; LePoire, D.; Biwer, B. M.; Cheng, J.; Arnish, J.; Yu, C.; Chen, S. Y.; Mo, T.; Abu-Eid, R.; Thaggard, M.; Environmental Assessment; NRC

    2002-01-01

    Sensitive parameter distributions were identified with the use of probabilistic analysis in the RESRAD computer code. RESRAD is a multimedia pathway analysis code designed to evaluate radiological exposures resulting from radiological contamination in soil. The dose distribution was obtained by using a set of default parameter distribution/values. Most of the variations in the output dose distribution could be attributed to uncertainty in a small set of input parameters that could be considered as sensitive parameter distributions. The identification of the sensitive parameters is a first step in the prioritization of future research and information gathering. When site-specific parameter distribution/values are available for an actual site, the same process should be used with these site-specific data. Regression analysis used to identify sensitive parameters indicated that the dominant pathways depended on the radionuclide and source configurations. However, two parameter distributions were sensitive for many radionuclides: the external shielding factor when external exposure was the dominant pathway and the plant transfer factor when plant ingestion was the dominant pathway. No single correlation or regression coefficient can be used alone to identify sensitive parameters in all the cases. The coefficients are useful guides, but they have to be used in conjunction with other aids, such as scatter plots, and should undergo further analysis.

  6. Interconnection-Wide Transmission Planning Initiative: Topic...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    A, Interconnection-Level Analysis and Planning Interconnection-Wide Transmission Planning Initiative: Topic A, Interconnection-Level Analysis and Planning A description of the ...

  7. Uncertainty and sensitivity analysis of food pathway results with the MACCS Reactor Accident Consequence Model

    SciTech Connect (OSTI)

    Helton, J.C.; Johnson, J.D.; Rollstin, J.A.; Shiver, A.W.; Sprung, J.L.

    1995-01-01

    Uncertainty and sensitivity analysis techniques based on Latin hypercube sampling, partial correlation analysis and stepwise regression analysis are used in an investigation with the MACCS model of the food pathways associated with a severe accident at a nuclear power station. The primary purpose of this study is to provide guidance on the variables to be considered in future review work to reduce the uncertainty in the important variables used in the calculation of reactor accident consequences. The effects of 87 imprecisely-known input variables on the following reactor accident consequences are studied: crop growing season dose, crop long-term dose, milk growing season dose, total food pathways dose, total ingestion pathways dose, total long-term pathways dose, area dependent cost, crop disposal cost, milk disposal cost, condemnation area, crop disposal area and milk disposal area. When the predicted variables are considered collectively, the following input variables were found to be the dominant contributors to uncertainty: fraction of cesium deposition on grain fields that is retained on plant surfaces and transferred directly to grain, maximum allowable ground concentrations of Cs-137 and Sr-90 for production of crops, ground concentrations of Cs-134, Cs-137 and I-131 at which the disposal of milk will be initiated due to accidents that occur during the growing season, ground concentrations of Cs-134, I-131 and Sr-90 at which the disposal of crops will be initiated due to accidents that occur during the growing season, rate of depletion of Cs-137 and Sr-90 from the root zone, transfer of Sr-90 from soil to legumes, transfer of Cs-137 from soil to pasture, transfer of cesium from animal feed to meat, and the transfer of cesium, iodine and strontium from animal feed to milk.

  8. Aligning ontologies and integrating textual evidence for pathway analysis of microarray data

    SciTech Connect (OSTI)

    Gopalan, Banu; Posse, Christian; Sanfilippo, Antonio P.; Stenzel-Poore, Mary; Stevens, S.L.; Castano, Jose; Beagley, Nathaniel; Riensche, Roderick M.; Baddeley, Bob; Simon, R.P.; Pustejovsky, James

    2006-10-08

    Expression arrays are introducing a paradigmatic change in biology by shifting experimental approaches from single gene studies to genome-level analysis, monitoring the ex-pression levels of several thousands of genes in parallel. The massive amounts of data obtained from the microarray data needs to be integrated and interpreted to infer biological meaning within the context of information-rich pathways. In this paper, we present a methodology that integrates textual information with annotations from cross-referenced ontolo-gies to map genes to pathways in a semi-automated way. We illustrate this approach and compare it favorably to other tools by analyzing the gene expression changes underlying the biological phenomena related to stroke. Stroke is the third leading cause of death and a major disabler in the United States. Through years of study, researchers have amassed a significant knowledge base about stroke, and this knowledge, coupled with new technologies, is providing a wealth of new scientific opportunities. The potential for neu-roprotective stroke therapy is enormous. However, the roles of neurogenesis, angiogenesis, and other proliferative re-sponses in the recovery process following ischemia and the molecular mechanisms that lead to these processes still need to be uncovered. Improved annotation of genomic and pro-teomic data, including annotation of pathways in which genes and proteins are involved, is required to facilitate their interpretation and clinical application. While our approach is not aimed at replacing existing curated pathway databases, it reveals multiple hidden relationships that are not evident with the way these databases analyze functional groupings of genes from the Gene Ontology.

  9. TEC Communications Topic Group

    Office of Environmental Management (EM)

    procurement - Routing criteriaemergency preparedness Tribal Issues Topic Group * TEPP Navajo Nation (Tom Clawson) - 1404 - Needs Assessment * Identified strengths and...

  10. Advanced development of a pressurized ash agglomerating fluidized-bed coal gasification system: Topical report, Process analysis, FY 1983

    SciTech Connect (OSTI)

    1987-07-31

    KRW Energy Systems, Inc., is engaged in the continuing development of a pressurized, fluidized-bed gasification process at its Waltz Mill Site in Madison, Pennsylvania. The overall objective of the program is to demonstrate the viability of the KRW process for the environmentally-acceptable production of low- and medium-Btu fuel gas from a variety of fossilized carbonaceous feedstocks and industrial fuels. This report presents process analysis of the 24 ton-per-day Process Development Unit (PDU) operations and is a continuation of the process analysis work performed in 1980 and 1981. Included is work performed on PDU process data; gasification; char-ash separation; ash agglomeration; fines carryover, recycle, and consumption; deposit formation; materials; and environmental, health, and safety issues. 63 figs., 43 tabs.

  11. Well-to-wheels analysis of fast pyrolysis pathways with the GREET model.

    SciTech Connect (OSTI)

    Han, J.; Elgowainy, A.; Palou-Rivera, I.; Dunn, J.B.; Wang, M.Q.

    2011-12-01

    The pyrolysis of biomass can help produce liquid transportation fuels with properties similar to those of petroleum gasoline and diesel fuel. Argonne National Laboratory conducted a life-cycle (i.e., well-to-wheels [WTW]) analysis of various pyrolysis pathways by expanding and employing the Greenhouse Gases, Regulated Emissions, and Energy Use in Transportation (GREET) model. The WTW energy use and greenhouse gas (GHG) emissions from the pyrolysis pathways were compared with those from the baseline petroleum gasoline and diesel pathways. Various pyrolysis pathway scenarios with a wide variety of possible hydrogen sources, liquid fuel yields, and co-product application and treatment methods were considered. At one extreme, when hydrogen is produced from natural gas and when bio-char is used for process energy needs, the pyrolysis-based liquid fuel yield is high (32% of the dry mass of biomass input). The reductions in WTW fossil energy use and GHG emissions relative to those that occur when baseline petroleum fuels are used, however, is modest, at 50% and 51%, respectively, on a per unit of fuel energy basis. At the other extreme, when hydrogen is produced internally via reforming of pyrolysis oil and when bio-char is sequestered in soil applications, the pyrolysis-based liquid fuel yield is low (15% of the dry mass of biomass input), but the reductions in WTW fossil energy use and GHG emissions are large, at 79% and 96%, respectively, relative to those that occur when baseline petroleum fuels are used. The petroleum energy use in all scenarios was restricted to biomass collection and transportation activities, which resulted in a reduction in WTW petroleum energy use of 92-95% relative to that found when baseline petroleum fuels are used. Internal hydrogen production (i.e., via reforming of pyrolysis oil) significantly reduces fossil fuel use and GHG emissions because the hydrogen from fuel gas or pyrolysis oil (renewable sources) displaces that from fossil fuel

  12. TEC Communications Topic Group

    Office of Environmental Management (EM)

    Tribal Issues Topic Group Judith Holm, Chair April 21, 2004 Albuquerque, NM Tribal Issues Topic Group * February Tribal Summit with Secretary of Energy (Kristen Ellis, CI) - Held in conjunction with NCAI mid-year conference - First Summit held in response to DOE Indian Policy - Addressed barriers to communication and developing framework for interaction Tribal Issues Topic Group * Summit (continued) - Federal Register Notice published in March soliciting input on how to improve summit process

  13. UNIRIB: Physics Topics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Physics Topics Research Capitalizing on the strengths of nine collaborating research ... Ion Beam (UNIRIB) consortium is conducting research at the forefront of nuclear physics. ...

  14. Evaulation of power-reactor fuel-rod-analysis capabilities. Phase 1 topical report. Volume 2. Code evaluation. [PWR; BWR

    SciTech Connect (OSTI)

    Coleman, D.R.

    1983-09-01

    FRAPCON-2 (V1M4) was applied to generate fuel performance predictions for 60 rods of a recently evaluated power reactor data sample. Rod design, operational, and performance data was obtained from the RPRI Fuel Performance Data Base. The data was systematically processed to generate code input parameters. FRAPCON was initially applied for scoping studies to identify the best estimate mechanical response and fission gas release modeling options. Based on final scoping results, the balance of rods were analyzed with FRACAS-2 mechanics and FASTGRASS gas release models. Comparisons between measured and calculated fuel and cladding deformation, fission gas release, internal pressure, and gas composition are presented and interpreted relative to code error magnitudes, distributions, and trends versus rod design and operating parameters. The results indicate the FRAPCON-2 has best estimate capability for analysis of moderate duty fuel rod performance, provided that rod fabrication parameters are well characterized, and the fuel is dimensionally stable.

  15. Analysis of fruitland water production treatment and disposal, San Juan Basin. Topical report, October 1991-March 1993

    SciTech Connect (OSTI)

    Cox, D.O.; Decker, A.D.; Stevens, S.H.

    1993-06-01

    The San Juan Basin produces more coalbed methane than the rest of the world combined. Brackish water is produced with the gas. Water production climbed from 40,000 barrels per day in 1989 to 115,000 bpd by late 1992. Underground injection is used to dispose of virtually all the produced water. Water production is projected to increase to 180,000 bpd in 1995. 650 million to 1.1 billion barrels are projected to be produced over the next 20 years. Restricted injection capacity and aquifer storage capacity may necessitate additional disposal wells and, ultimately, other methods to dispose of the water. Alternative treatment technologies, especially electrodialysis and/or reverse osmosis, may be applicable at costs of $0.17 to $0.22 per barrel, a considerable savings over the $0.80 to $1.00/bbl cost of deep injection. With suitable treatment, the majority of the produced water could be made suitable for agricultural or municipal uses. Reservoir analysis and simulations indicate stimulations can be optimized, and that heating water prior to injection might increase injectivity in some wells.

  16. More About "Topic A" and "Topic B" Awards | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    More About "Topic A" and "Topic B" Awards More About "Topic A" and "Topic B" Awards The awards pursuant to the Department of Energy's Interconnection-wide Transmission Planning Initiative cover two broad topics. "Topic A" covers Interconnection-Level Analysis and Planning. "Topic B" covers Cooperation Among States on Electric Resource Planning and Priorities, where the states will develop input to the Topic A analyses and perform other

  17. ALL-PATHWAYS DOSE ANALYSIS FOR THE PORTSMOUTH ON-SITE WASTE DISPOSAL FACILITY

    SciTech Connect (OSTI)

    Smith, F.; Phifer, M.

    2014-04-10

    A Portsmouth On-Site Waste Disposal Facility (OSWDF) All-Pathways analysis has been conducted that considers the radiological impacts to a resident farmer. It is assumed that the resident farmer utilizes a farm pond contaminated by the OSWDF to irrigate a garden and pasture and water livestock from which food for the resident farmer is obtained, and that the farmer utilizes groundwater from the Berea sandstone aquifer for domestic purposes (i.e. drinking water and showering). As described by FBP 2014b the Hydrologic Evaluation of Landfill Performance (HELP) model (Schroeder et al. 1994) and the Surface Transport Over Multiple Phases (STOMP) model (White and Oostrom 2000, 2006) were used to model the flow and transport from the OSWDF to the Points of Assessment (POAs) associated with the 680-ft elevation sandstone layer (680 SSL) and the Berea sandstone aquifer. From this modeling the activity concentrations radionuclides were projected over time at the POAs. The activity concentrations were utilized as input to a GoldSimTM (GTG 2010) dose model, described herein, in order to project the dose to a resident farmer over time. A base case and five sensitivity cases were analyzed. The sensitivity cases included an evaluation of the impacts of using a conservative inventory, an uncased well to the Berea sandstone aquifer, a low waste zone uranium distribution coefficient (Kd), different transfer factors, and reference person exposure parameters (i.e. at 95 percentile). The maximum base case dose within the 1,000 year assessment period was projected to be 1.5E-14 mrem/yr, and the maximum base case dose at any time less than 10,000 years was projected to be 0.002 mrem/yr. The maximum projected dose of any sensitivity case was approximately 2.6 mrem/yr associated with the use of an uncased well to the Berea sandstone aquifer. This sensitivity case is considered very unlikely because it assumes leakage from the location of greatest concentration in the 680 SSL in to the

  18. Presentation: QER Energy Topics

    Office of Energy Efficiency and Renewable Energy (EERE)

    A briefing to the Secretary's Energy Advisory Board on QER Energy Topics (Energy Flows, Water Flows, and Program for Climate Model Diagnosis and Intercomparison) prepared by: A.J. Simon, Lawrence Livermore National Laboratory

  19. ARM - Topic List

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    TeachersTopic List Outreach Home Room News Publications Traditional Knowledge Kiosks Barrow, Alaska Tropical Western Pacific Site Tours Contacts Students Study Hall About ARM Global Warming FAQ Just for Fun Meet our Friends Cool Sites Teachers Teachers' Toolbox Lesson Plans Topic List Atmosphere Atmospheric Heat Budget Atmospheric Pressure Composition of the Atmosphere Evolution of the Atmosphere Mesosphere Stratosphere Thermosphere Troposphere Oceans Oceans Sea Surface and Sea Level Weather and

  20. Tracking topic birth and death in LDA.

    SciTech Connect (OSTI)

    Wilson, Andrew T.; Robinson, David Gerald

    2011-09-01

    Most topic modeling algorithms that address the evolution of documents over time use the same number of topics at all times. This obscures the common occurrence in the data where new subjects arise and old ones diminish or disappear entirely. We propose an algorithm to model the birth and death of topics within an LDA-like framework. The user selects an initial number of topics, after which new topics are created and retired without further supervision. Our approach also accommodates many of the acceleration and parallelization schemes developed in recent years for standard LDA. In recent years, topic modeling algorithms such as latent semantic analysis (LSA)[17], latent Dirichlet allocation (LDA)[10] and their descendants have offered a powerful way to explore and interrogate corpora far too large for any human to grasp without assistance. Using such algorithms we are able to search for similar documents, model and track the volume of topics over time, search for correlated topics or model them with a hierarchy. Most of these algorithms are intended for use with static corpora where the number of documents and the size of the vocabulary are known in advance. Moreover, almost all current topic modeling algorithms fix the number of topics as one of the input parameters and keep it fixed across the entire corpus. While this is appropriate for static corpora, it becomes a serious handicap when analyzing time-varying data sets where topics come and go as a matter of course. This is doubly true for online algorithms that may not have the option of revising earlier results in light of new data. To be sure, these algorithms will account for changing data one way or another, but without the ability to adapt to structural changes such as entirely new topics they may do so in counterintuitive ways.

  1. SPECIAL ANALYSIS AIR PATHWAY MODELING OF E-AREA LOW-LEVEL WASTE FACILITY

    SciTech Connect (OSTI)

    Hiergesell, R.; Taylor, G.

    2011-08-30

    This Special Analysis (SA) was initiated to address a concern expressed by the Department of Energy's Low Level Waste Disposal Facility Federal Review Group (LFRG) Review Team during their review of the 2008 E-Area Performance Assessment (PA) (WSRC, 2008). Their concern was the potential for overlapping of atmospheric plumes, emanating from the soil surface above SRS LLW disposal facilities within the E-Area, to contribute to the dose received by a member of the public during the Institutional Control (IC) period. The implication of this concern was that the dose to the maximally-exposed individual (MEI) located at the SRS boundary might be underestimated during this time interval. To address this concern a re-analysis of the atmospheric pathway releases from E-Area was required. In the process of developing a new atmospheric release model (ARM) capable of addressing the LFRG plume overlap concern, it became obvious that new and better atmospheric pathway disposal limits should be developed for each of the E-Area disposal facilities using the new ARM. The scope of the SA was therefore expanded to include the generation of these new limits. The initial work conducted in this SA was to develop a new ARM using the GoldSim{reg_sign} program (GTG, 2009). The model simulates the subsurface vapor diffusion of volatile radionuclides as they release from E-Area disposal facility waste zones and migrate to the land surface. In the process of this work, many new features, including several new physical and chemical transport mechanisms, were incorporated into the model. One of the most important improvements was to incorporate a mechanism to partition volatile contaminants across the water-air interface within the partially saturated pore space of the engineered and natural materials through which vapor phase transport occurs. A second mechanism that was equally important was to incorporate a maximum concentration of 1.9E-07 Ci/m{sup 3} of {sup 14}CO{sub 2} in the air

  2. Topical Committee | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Topical Committee Topical Committee In the interest of optimum technology transfer, the DOE Technical Standards Program (TSP) has set up a network of topical committees. These committees provide a forum for communication across the DOE complex on technical standards related activities. If you would like information about a specific topical committee, or wish to join one of the groups, we've provided a roster of TSP Topical Committees and corresponding Topical Committee Chairpersons. Expectations

  3. Flux analysis of central metabolic pathways in Geobactermetallireducens during reduction of solubleFe(III)-NTA

    SciTech Connect (OSTI)

    Tang, Yinjie J.; Chakraborty, Romy; Garcia-Martin, Hector; Chu,Jeannie; Hazen, Terry C.; Keasling, Jay D.

    2007-01-01

    We analyzed the carbon fluxes in the central metabolism ofGeobacter metallireducens strain GS-15 using 13C isotopomer modeling.Acetate labeled in the 1st or 2nd position was the sole carbon source,and Fe-NTA was the sole terminal electron acceptor. The measured labeledacetate uptake rate was 21 mmol/gdw/h in the exponential growth phase.The resulting isotope labeling pattern of amino acids allowed an accuratedetermination of the in vivo global metabolic reaction rates (fluxes)through the central metabolic pathways using a computational isotopomermodel. The tracer experiments showed that G. metallireducens containedcomplete biosynthesis pathways for essential metabolism, and this strainmight also have an unusual isoleucine biosynthesis route (usingacetyl-CoA and pyruvate as the precursors). The model indicated that over90 percent of the acetate was completely oxidized to CO2 via a completetricarboxylic acid (TCA) cycle while reducing iron. Pyruvate carboxylaseand phosphoenolpyruvate carboxykinase were present under theseconditions, but enzymes in the glyoxylate shunt and malic enzyme wereabsent. Gluconeogenesis and the pentose phosphate pathway were mainlyemployed for biosynthesis and accounted for less than 3 percent of totalcarbon consumption. The model also indicated surprisingly highreversibility in the reaction between oxoglutarate and succinate. Thisstep operates close to the thermodynamic equilibrium possibly becausesuccinate is synthesized via a transferase reaction, and the conversionof oxoglutarate to succinate is a rate limiting step for carbonmetabolism. These findings enable a better understanding of therelationship between genome annotation and extant metabolic pathways inG. metallireducens.

  4. Focus Group Meeting (Topical Meeting)

    Office of Energy Efficiency and Renewable Energy (EERE)

    Topical Meeting - Training Meeting agenda, summary and information package Meeting Date: April 30, 2008

  5. Featured Topic Pages

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Featured Topic Pages * Renowned scientists, with information about the scientists' R&D results * Significant DOE research disciplines, with R&D results * Manhattan Project, including scientists and key events Laureates * Nobel Prize winners associated with DOE and predecessor agencies * Winners of the Enrico Fermi Award, a U.S. Presidential award Database * Selected documents about noteworthy R&D results * Documents and individual pages searchable by word or phrase * Tag cloud

  6. Manufacturing Innovation Topics Workshop

    Office of Energy Efficiency and Renewable Energy (EERE)

    The Advanced Manufacturing Office (AMO) and the Office of the Secretary of Defense Manufacturing Technology Program (OSD ManTech) will host a workshop to discuss AMO's recent Request for Information (RFI) on Clean Energy Manufacturing Topic Areas as well as the recent areas of interest announced by OSD ManTech for a new Manufacturing Innovation Institute on October 8-9, 2014 in Fort Worth, TX.

  7. Comparative genomic analysis of nine Sphingobium strains: Insights into their evolution and hexachlorocyclohexane (HCH) degradation pathways

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Verma, Helianthous; Kumar, Roshan; Oldach, Phoebe; Sangwan, Naseer; Khurana, Jitendra P.; Gilbert, Jack A.; Lal, Rup

    2014-11-23

    Background: Sphingobium spp. are efficient degraders of a wide range of chlorinated and aromatic hydrocarbons. In particular, strains which harbour the lin pathway genes mediating the degradation of hexachlorocyclohexane (HCH) isomers are of interest due to the widespread persistence of this contaminant. Here, we examined the evolution and diversification of the lin pathway under the selective pressure of HCH, by comparing the draft genomes of six newly-sequenced Sphingobium spp. (strains LL03, DS20, IP26, HDIPO4, P25 and RL3) isolated from HCH dumpsites, with three existing genomes (S. indicum B90A, S. japonicum UT26S and Sphingobium sp. SYK6). Results: Efficient HCH degraders phylogeneticallymore » clustered in a closely related group comprising of UT26S, B90A, HDIPO4 and IP26, where HDIPO4 and IP26 were classified as subspecies with ANI value >98%. Less than 10% of the total gene content was shared among all nine strains, but among the eight HCH-associated strains, that is all except SYK6, the shared gene content jumped to nearly 25%. Genes associated with nitrogen stress response and two-component systems were found to be enriched. The strains also housed many xenobiotic degradation pathways other than HCH, despite the absence of these xenobiotics from isolation sources. In addition, these strains, although non-motile, but posses flagellar assembly genes. While strains HDIPO4 and IP26 contained the complete set of lin genes, DS20 was entirely devoid of lin genes (except linKLMN) whereas, LL03, P25 and RL3 were identified as lin deficient strains, as they housed incomplete lin pathways. Further, in HDIPO4, linA was found as a hybrid of two natural variants i.e., linA1 and linA2 known for their different enantioselectivity. In conclusion, the bacteria isolated from HCH dumpsites provide a natural testing ground to study variations in the lin system and their effects on degradation efficacy. Further, the diversity in the lin gene sequences and copy number, their

  8. Waste-to-wheel analysis of anaerobic-digestion-based renewable natural gas pathways with the GREET model.

    SciTech Connect (OSTI)

    Han, J.; Mintz, M.; Wang, M.

    2011-12-14

    In 2009, manure management accounted for 2,356 Gg or 107 billion standard cubic ft of methane (CH{sub 4}) emissions in the United States, equivalent to 0.5% of U.S. natural gas (NG) consumption. Owing to the high global warming potential of methane, capturing and utilizing this methane source could reduce greenhouse gas (GHG) emissions. The extent of that reduction depends on several factors - most notably, how much of this manure-based methane can be captured, how much GHG is produced in the course of converting it to vehicular fuel, and how much GHG was produced by the fossil fuel it might displace. A life-cycle analysis was conducted to quantify these factors and, in so doing, assess the impact of converting methane from animal manure into renewable NG (RNG) and utilizing the gas in vehicles. Several manure-based RNG pathways were characterized in the GREET (Greenhouse gases, Regulated Emissions, and Energy use in Transportation) model, and their fuel-cycle energy use and GHG emissions were compared to petroleum-based pathways as well as to conventional fossil NG pathways. Results show that despite increased total energy use, both fossil fuel use and GHG emissions decline for most RNG pathways as compared with fossil NG and petroleum. However, GHG emissions for RNG pathways are highly dependent on the specifics of the reference case, as well as on the process energy emissions and methane conversion factors assumed for the RNG pathways. The most critical factors are the share of flared controllable CH{sub 4} and the quantity of CH{sub 4} lost during NG extraction in the reference case, the magnitude of N{sub 2}O lost in the anaerobic digestion (AD) process and in AD residue, and the amount of carbon sequestered in AD residue. In many cases, data for these parameters are limited and uncertain. Therefore, more research is needed to gain a better understanding of the range and magnitude of environmental benefits from converting animal manure to RNG via AD.

  9. Pathway and Resource Overview (Presentation)

    SciTech Connect (OSTI)

    Ruth, M. F.

    2009-11-16

    This presentation provides information about hydrogen pathway analysis, which is analysis of the total levelized cost (including return on investment). Well-to-wheels (WTW) energy use, and WTW emissions for hydrogen production, delivery, and distribution pathways.

  10. Integrated analysis of breast cancer cell lines reveals unique signaling pathways

    SciTech Connect (OSTI)

    Heiser, Laura M.; Wang, Nicholas J.; Talcott, Carolyn L.; Laderoute, Keith R.; Knapp, Merrill; Guan, Yinghui; Hu, Zhi; Ziyad, Safiyyah; Weber, Barbara L.; Laquerre, Sylvie; Jackson, Jeffrey R.; Wooster, Richard F.; Kuo, Wen-Lin; Gray, Joe W.; Spellman, Paul T.

    2009-03-31

    Cancer is a heterogeneous disease resulting from the accumulation of genetic defects that negatively impact control of cell division, motility, adhesion and apoptosis. Deregulation in signaling along the EGFR-MAPK pathway is common in breast cancer, though the manner in which deregulation occurs varies between both individuals and cancer subtypes. We were interested in identifying subnetworks within the EGFR-MAPK pathway that are similarly deregulated across subsets of breast cancers. To that end, we mapped genomic, transcriptional and proteomic profiles for 30 breast cancer cell lines onto a curated Pathway Logic symbolic systems model of EGFR-MEK signaling. This model was comprised of 539 molecular states and 396 rules governing signaling between active states. We analyzed these models and identified several subtype specific subnetworks, including one that suggested PAK1 is particularly important in regulating the MAPK cascade when it is over-expressed. We hypothesized that PAK1 overexpressing cell lines would have increased sensitivity to MEK inhibitors. We tested this experimentally by measuring quantitative responses of 20 breast cancer cell lines to three MEK inhibitors. We found that PAK1 over-expressing luminal breast cancer cell lines are significantly more sensitive to MEK inhibition as compared to those that express PAK1 at low levels. This indicates that PAK1 over-expression may be a useful clinical marker to identify patient populations that may be sensitive to MEK inhibitors. All together, our results support the utility of symbolic system biology models for identification of therapeutic approaches that will be effective against breast cancer subsets.

  11. Improved Protein Arrays for Quantitative Systems Analysis of the Dynamics of Signaling Pathway Interactions

    SciTech Connect (OSTI)

    YANG, CHIN-RANG

    2013-12-11

    Astronauts and workers in nuclear plants who repeatedly exposed to low doses of ionizing radiation (IR, <10 cGy) are likely to incur specific changes in signal transduction and gene expression in various tissues of their body. Remarkable advances in high throughput genomics and proteomics technologies enable researchers to broaden their focus from examining single gene/protein kinetics to better understanding global gene/protein expression profiling and biological pathway analyses, namely Systems Biology. An ultimate goal of systems biology is to develop dynamic mathematical models of interacting biological systems capable of simulating living systems in a computer. This Glue Grant is to complement Dr. Boothman’s existing DOE grant (No. DE-FG02-06ER64186) entitled “The IGF1/IGF-1R-MAPK-Secretory Clusterin (sCLU) Pathway: Mediator of a Low Dose IR-Inducible Bystander Effect” to develop sensitive and quantitative proteomic technology that suitable for low dose radiobiology researches. An improved version of quantitative protein array platform utilizing linear Quantum dot signaling for systematically measuring protein levels and phosphorylation states for systems biology modeling is presented. The signals are amplified by a confocal laser Quantum dot scanner resulting in ~1000-fold more sensitivity than traditional Western blots and show the good linearity that is impossible for the signals of HRP-amplification. Therefore this improved protein array technology is suitable to detect weak responses of low dose radiation. Software is developed to facilitate the quantitative readout of signaling network activities. Kinetics of EGFRvIII mutant signaling was analyzed to quantify cross-talks between EGFR and other signaling pathways.

  12. Interconnection-Wide Transmission Planning Initiative: Topic A,

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Interconnection-Level Analysis and Planning | Department of Energy A, Interconnection-Level Analysis and Planning Interconnection-Wide Transmission Planning Initiative: Topic A, Interconnection-Level Analysis and Planning A description of the requirements for Topic A for all Interconnections under the Interconnection-Wide Transmission Planning Initiative, part of the American Recovery and Reinvestment Act. Interconnection-Wide Transmission Planning Initiative: Topic A, Interconnection-Level

  13. Pathway Analysis Revealed Potential Diverse Health Impacts of Flavonoids that Bind Estrogen Receptors

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Ye, Hao; Ng, Hui; Sakkiah, Sugunadevi; Ge, Weigong; Perkins, Roger; Tong, Weida; Hong, Huixiao

    2016-03-26

    Flavonoids are frequently used as dietary supplements in the absence of research evidence regarding health benefits or toxicity. Furthermore, ingested doses could far exceed those received from diet in the course of normal living. Some flavonoids exhibit binding to estrogen receptors (ERs) with consequential vigilance by regulatory authorities at the U.S. EPA and FDA. Regulatory authorities must consider both beneficial claims and potential adverse effects, warranting the increases in research that has spanned almost two decades. Here, we report pathway enrichment of 14 targets from the Comparative Toxicogenomics Database (CTD) and the Herbal Ingredients’ Targets (HIT) database for 22 flavonoidsmore » that bind ERs. The selected flavonoids are confirmed ER binders from our earlier studies, and were here found in mainly involved in three types of biological processes, ER regulation, estrogen metabolism and synthesis, and apoptosis. Besides cancers, we conjecture that the flavonoids may affect several diseases via apoptosis pathways. We find diseases such as amyotrophic lateral sclerosis, viral myocarditis and non-alcoholic fatty liver disease could be implicated. More generally, apoptosis processes may be importantly evolved biological functions of flavonoids that bind ERs and high dose ingestion of those flavonoids could adversely disrupt the cellular apoptosis process.« less

  14. TEC Working Group Topic Groups Archives Consolidated Grant Topic Group |

    Office of Environmental Management (EM)

    Department of Energy Consolidated Grant Topic Group TEC Working Group Topic Groups Archives Consolidated Grant Topic Group The Consolidated Grant Topic Group arose from recommendations provided by the TEC and other external parties to the DOE Senior Executive Transportation Forum in July 1998. It was proposed that the consolidation of multiple funding streams from numerous DOE sources into a single grant would provide a more equitable and efficient means of assistance to States and Tribes

  15. Final Technical Report: Genetic and Molecular Analysis of a new control pathway in assimilate partitioning.

    SciTech Connect (OSTI)

    Bush, Daniel, R.

    2009-03-10

    Assimilate partitioning refers to the systemic distribution of photoassimilate from sites of primary assimilation (source tissue) to import-dependent tissues and organs (sinks). One of the defining questions in this area is how plants balance source productivity with sink demand. We discovered a sucrose-sensing signal transduction pathway that controls the activity of BvSUT1, a proton-sucrose symporter in sugar beet leaf tissue. Sucrose symporters are responsible for sucrose accumulation in the phloem of many plants and, therefore, they mediate the pivotal step in the long-distance transport of photoassimilate to non-photosynthetic tissues, such as roots and seed. We previously showed that sucrose transport activity is directly proportional to the transcription rate of BvSUT1 and that symporter mRNA and protein have high rates of turnover with half-lives on the order of 2 h. We further demonstrated that symporter transcription is regulated by sucrose levels in the leaf and that sucrose-dependent regulation of BvSUT1 transcription is mediated, at least in part, by a protein phosphorylation relay pathway. The goal of the experiments during this current grant were to use genetic and molecular approaches to identify essential components of this vital regulatory system. The initial objectives were to: (1) to characterize Arabidopsis mutants we've isolated that are resistant to growth inhibition by sucrose analogues that are recognized by the sucrose-sensor, (2) to screen for loss of function mutants in BvSUT1-promoter:luciferase transgenic plants that no longer respond to sucrose accumulation in the leaf using non-destructive visualization of luciferase activity, (3) to use gel mobility-shift assays and nuclease protection experiments to identify cis elements in the symporter promoter and DNA-binding proteins that are involved in sucrose regulation of symporter expression.

  16. TECHNICAL STANDARDS PROGRAM TOPICAL COMMITTEES

    Broader source: Energy.gov [DOE]

    PurposeThis procedure describes how topical committees are organized and recognized under the Technical Standards Program. 

  17. Techno-Economic Boundary Analysis of Biological Pathways to Hydrogen Production (2009)

    Broader source: Energy.gov [DOE]

    Presentation by Brian James, Strategic Analysis Inc., at the Biological Hydrogen Production Workshop held September 24-25, 2013, at the National Renewable Energy Laboratory in Golden, Colorado.

  18. Conformational selection in a protein-protein interaction revealed by dynamic pathway analysis

    SciTech Connect (OSTI)

    Chakrabarti, Kalyan S.; Agafonov, Roman V.; Pontiggia, Francesco; Otten, Renee; Higgins, Matthew K.; Schertler, Gebhard F. X.; Oprian, Daniel D.; Kern, Dorothee

    2015-12-24

    Molecular recognition plays a central role in biology, and protein dynamics has been acknowledged to be important in this process. However, it is highly debated whether conformational changes happen before ligand binding to produce a binding-competent state (conformational selection) or are caused in response to ligand binding (induced fit). Proposals for both mechanisms in protein/protein recognition have been primarily based on structural arguments. However, the distinction between them is a question of the probabilities of going via these two opposing pathways. Here we present a direct demonstration of exclusive conformational selection in protein/protein recognition by measuring the flux for rhodopsin kinase binding to its regulator recoverin, an important molecular recognition in the vision system. Using NMR spectroscopy, stopped-flow kinetics and isothermal titration calorimetry we show that recoverin populates a minor conformation in solution that exposes a hydrophobic binding pocket responsible for binding rhodopsin kinase. Lastly, protein dynamics in free recoverin limits the overall rate of binding.

  19. Conformational selection in a protein-protein interaction revealed by dynamic pathway analysis

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Chakrabarti, Kalyan S.; Agafonov, Roman V.; Pontiggia, Francesco; Otten, Renee; Higgins, Matthew K.; Schertler, Gebhard F. X.; Oprian, Daniel D.; Kern, Dorothee

    2015-12-24

    Molecular recognition plays a central role in biology, and protein dynamics has been acknowledged to be important in this process. However, it is highly debated whether conformational changes happen before ligand binding to produce a binding-competent state (conformational selection) or are caused in response to ligand binding (induced fit). Proposals for both mechanisms in protein/protein recognition have been primarily based on structural arguments. However, the distinction between them is a question of the probabilities of going via these two opposing pathways. Here we present a direct demonstration of exclusive conformational selection in protein/protein recognition by measuring the flux for rhodopsinmore » kinase binding to its regulator recoverin, an important molecular recognition in the vision system. Using NMR spectroscopy, stopped-flow kinetics and isothermal titration calorimetry we show that recoverin populates a minor conformation in solution that exposes a hydrophobic binding pocket responsible for binding rhodopsin kinase. Lastly, protein dynamics in free recoverin limits the overall rate of binding.« less

  20. Techno-Economic Boundary Analysis of Biological Pathways to Hydrogen Production (2009)

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    September 2013 Presentation to: Biological Hydrogen Production Workshop By: Brian D. James Strategic Analysis Inc. Bjames@sainc.com (703) 778-7114 1 This presentation does not contain any proprietary, confidential, or otherwise restricted information * DOE/NREL Bio H 2 Working Group * Roxanne Garland, DOE * Ali Jalalzadeh-Azar, NREL * Mike Seibert, NREL * Maria Ghirardi, NREL * Pin-Ching Maness, NREL * Tasio Melis, UC Berkeley * Gerald C. Dismukes - Princeton University * Bruce Logan, Penn

  1. Special Topics and Data Reports

    U.S. Energy Information Administration (EIA) Indexed Site

    (HTML format) Yellow Arrow Energy Consumption and Expenditures (HTML format) adobe logo Download Acrobat Reader for viewing PDF files. Special Topics and Data Reports...

  2. Innovative Topics for Advanced Biofuels

    Broader source: Energy.gov (indexed) [DOE]

    Innovative Topics for Advanced Biofuels Jonathan Male, Ph.D. PNNL Report-Out Webinar ... into biomass sugars to feed advanced biofuels Separations - Compatibility with ...

  3. Session on computation in biological pathways

    SciTech Connect (OSTI)

    Karp, P.D.; Riley, M.

    1996-12-31

    The papers in this session focus on the development of pathway databases and computational tools for pathway analysis. The discussion involves existing databases of sequenced genomes, as well as techniques for studying regulatory pathways.

  4. Fossil Energy Technical Assistance Topic Areas | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Fossil Energy Technical Assistance Topic Areas Fossil Energy Technical Assistance Topic Areas Potential Technical Assistance Topic Areas in the Office of Fossil Energy EPA Regulations - Analysis to Support Planning Contact: Jordan Kislear Storage Infrastructure Contact: Mark Ackiewicz Major Demonstrations Contact: Joe Giove Department of Energy and National Association of Regulatory Utility Commissioners (NARUC) Contact: Doug Middleton Fossil Capacity and Resources in Your State or Region

  5. Events & Topics | Metrolink Tour | Photosynthetic Antenna Research Center

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Events & Topics | Metrolink Tour Events & Topics | Metrolink Tour

  6. Decision Point 1 Topical Report

    SciTech Connect (OSTI)

    Yablonsky, Al; Barsoumian, Shant; Legere, David

    2013-05-01

    This Topical Report addresses accomplishments achieved during Phase 2a of the SkyMine® Carbon Mineralization Pilot Project. The primary objectives of this project are to design, construct, and operate a system to capture CO2 from a slipstream of flue gas from a commercial coal-fired cement kiln, convert that CO2 to products having commercial value (i.e., beneficial use), show the economic viability of the CO2 capture and conversion process, and thereby advance the technology to the point of readiness for commercial scale demonstration and proliferation. The overall process is carbon negative, resulting in mineralization of CO2 that would otherwise be released into the atmosphere. The project will also substantiate market opportunities for the technology by sales of chemicals into existing markets, and identify opportunities to improve technology performance and reduce costs at the commercial scale. The project is being conducted in two phases. The primary objectives of Phase 1 were to elaborate proven SkyMine® process chemistry to commercial pilot-scale operation and complete the preliminary design for the pilot plant to be built and operated in Phase 2, complete a NEPA evaluation, and develop a comprehensive carbon life cycle analysis. The objective of the current Phase (2a) is to complete the detailed design of the pilot plant to be built in Phase 2b.

  7. Organic solvent topical report

    SciTech Connect (OSTI)

    COWLEY, W.L.

    1999-05-13

    This report provides the basis for closing the organic solvent safety issue. Sufficient information is presented to conclude that risk posed by an organic solvent fire is within risk evaluation guidelines. This report updates information contained in Analysis of Consequences of Postulated Solvent Fires in Hanford Site Waste Tanks. WHC-SD-WM-CN-032. Rev. 0A (Cowley et al. 1996). However, this document will not replace Cowley et al (1996) as the primary reference for the Basis for Interim Operation (BIO) until the recently submitted BIO amendment (Hanson 1999) is approved by the US Department of Energy. This conclusion depends on the use of controls for preventing vehicle fuel fires and for limiting the use of flame cutting in areas where hot metal can fall on the waste surface.The required controls are given in the Tank Waste Remediation System Technical Safety Requirements (Noorani 1997b). This is a significant change from the conclusions presented in Revision 0 of this report. Revision 0 of this calcnote concluded that some organic solvent fire scenarios exceeded risk evaluation guidelines, even with controls imposed.

  8. Missouri Botanical Gardens Tour | Events & Topics | Photosynthetic...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    | Events & Topics Missouri Botanical Gardens Tour | Events & Topics PARC welcomed community members for our guided tour of the Missouri Botanical Garden. http:...

  9. Events & Topics In Bioenergy | Photosynthetic Antenna Research...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Events & Topics In Bioenergy Events & Topics In Bioenergy Dr. Chenyang Lu Smart Building with Wireless Sensor Networks Dr. Joseph Cullen "Measuring the Environmental Benefits of ...

  10. Topic A Note: Includes STEPS Subtopic

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Topic A Note: Includes STEPS Subtopic 33 Total Projects Developing and Enhancing Workforce Training Programs

  11. Brazil-Pathways to a Low Carbon Economy | Open Energy Information

    Open Energy Info (EERE)

    Pathways to a Low Carbon Economy Jump to: navigation, search Name Pathways to a Low Carbon Economy for Brazil AgencyCompany Organization McKinsey and Company Topics...

  12. Hot topics from the Tevatron

    SciTech Connect (OSTI)

    Glenzinski, D.; /Fermilab

    2008-01-01

    The Tevatron Run-II began in March 2001. To date, both the CDF and D0 experiments have collected 1 fb{sup -1} of data each. The results obtained from this data set were summarized at this conference in 39 parallel session presentations covering a wide range of topics. The author summarizes the most important of those results here and comments on some of the prospects for the future.

  13. 2012 LANSCE Topical User Meeting

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    2 LANSCE Topical User Meeting January 9-10, 2012 The Office of Defense Programs is developing a long-term strategy for the construction of new experimental science facilities supporting NNSA missions. The new facilities will provide the critical science and technology capabilities necessary to execute the 21 st century responsibilities of NNSA in executing its mission and in supporting the broader national security agenda. The call focuses on large facilities with costs exceeding $100M. The NNSA

  14. Topic B Awardee: Western Governors' Association | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Western Governors' Association Topic B Awardee: Western Governors' Association For the Topic A input requirements of the award, the states and provinces in the Western Interconnection have formed a new committee -- the State and Provincial Steering Committee -- to provide input in regional transmission planning and analysis in the interconnection. The Committee will consist of representatives from each state and province in the Western Interconnection. Pending formal announcement, the Committee

  15. Comparative genomic analysis of nine Sphingobium strains: Insights into their evolution and hexachlorocyclohexane (HCH) degradation pathways

    SciTech Connect (OSTI)

    Verma, Helianthous; Kumar, Roshan; Oldach, Phoebe; Sangwan, Naseer; Khurana, Jitendra P.; Gilbert, Jack A.; Lal, Rup

    2014-11-23

    Background: Sphingobium spp. are efficient degraders of a wide range of chlorinated and aromatic hydrocarbons. In particular, strains which harbour the lin pathway genes mediating the degradation of hexachlorocyclohexane (HCH) isomers are of interest due to the widespread persistence of this contaminant. Here, we examined the evolution and diversification of the lin pathway under the selective pressure of HCH, by comparing the draft genomes of six newly-sequenced Sphingobium spp. (strains LL03, DS20, IP26, HDIPO4, P25 and RL3) isolated from HCH dumpsites, with three existing genomes (S. indicum B90A, S. japonicum UT26S and Sphingobium sp. SYK6). Results: Efficient HCH degraders phylogenetically clustered in a closely related group comprising of UT26S, B90A, HDIPO4 and IP26, where HDIPO4 and IP26 were classified as subspecies with ANI value >98%. Less than 10% of the total gene content was shared among all nine strains, but among the eight HCH-associated strains, that is all except SYK6, the shared gene content jumped to nearly 25%. Genes associated with nitrogen stress response and two-component systems were found to be enriched. The strains also housed many xenobiotic degradation pathways other than HCH, despite the absence of these xenobiotics from isolation sources. In addition, these strains, although non-motile, but posses flagellar assembly genes. While strains HDIPO4 and IP26 contained the complete set of lin genes, DS20 was entirely devoid of lin genes (except linKLMN) whereas, LL03, P25 and RL3 were identified as lin deficient strains, as they housed incomplete lin pathways. Further, in HDIPO4, linA was found as a hybrid of two natural variants i.e., linA1 and linA2 known for their different enantioselectivity. In conclusion, the bacteria isolated from HCH dumpsites provide a natural testing ground to study variations in the lin system and their

  16. Well-to-Wheels analysis of landfill gas-based pathways and their addition to the GREET model.

    SciTech Connect (OSTI)

    Mintz, M.; Han, J.; Wang, M.; Saricks, C.; Energy Systems

    2010-06-30

    Today, approximately 300 million standard cubic ft/day (mmscfd) of natural gas and 1600 MW of electricity are produced from the decomposition of organic waste at 519 U.S. landfills (EPA 2010a). Since landfill gas (LFG) is a renewable resource, this energy is considered renewable. When used as a vehicle fuel, compressed natural gas (CNG) produced from LFG consumes up to 185,000 Btu of fossil fuel and generates from 1.5 to 18.4 kg of carbon dioxide-equivalent (CO{sub 2}e) emissions per million Btu of fuel on a 'well-to-wheel' (WTW) basis. This compares with approximately 1.1 million Btu and 78.2 kg of CO{sub 2}e per million Btu for CNG from fossil natural gas and 1.2 million Btu and 97.5 kg of CO{sub 2}e per million Btu for petroleum gasoline. Because of the additional energy required for liquefaction, LFG-based liquefied natural gas (LNG) requires more fossil fuel (222,000-227,000 Btu/million Btu WTW) and generates more GHG emissions (approximately 22 kg CO{sub 2}e /MM Btu WTW) if grid electricity is used for the liquefaction process. However, if some of the LFG is used to generate electricity for gas cleanup and liquefaction (or compression, in the case of CNG), vehicle fuel produced from LFG can have no fossil fuel input and only minimal GHG emissions (1.5-7.7 kg CO{sub 2}e /MM Btu) on a WTW basis. Thus, LFG-based natural gas can be one of the lowest GHG-emitting fuels for light- or heavy-duty vehicles. This report discusses the size and scope of biomethane resources from landfills and the pathways by which those resources can be turned into and utilized as vehicle fuel. It includes characterizations of the LFG stream and the processes used to convert low-Btu LFG into high-Btu renewable natural gas (RNG); documents the conversion efficiencies and losses of those processes, the choice of processes modeled in GREET, and other assumptions used to construct GREET pathways; and presents GREET results by pathway stage. GREET estimates of well-to-pump (WTP), pump

  17. WTP Communications Strategy Discussion Topics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Discussion Topics For discussion at the April 7, 2015 PIC meeting Issue Managers: Bob Suyama, Dave Bernhard, Melanie Myers-Magnuson, Dirk Dunning, Liz Mattson, Pam Larsen, Ken Niles Some potential questions and areas that the TWC/PIC need to discuss in order to develop a Communica- tions Strategy for the Waste Treatment Plant. These questions represent the data that the TWC/PIC might need in order to provide a plan that will be of value to the Tri-Party Agencies and the Public and Stakeholders.

  18. Integrated analysis reveals that STAT3 is central to the crosstalk between HER/ErbB receptor signaling pathways in human mammary epithelial cells

    SciTech Connect (OSTI)

    Gong, Chunhong; Zhang, Yi; Shankaran, Harish; Resat, Haluk

    2015-01-01

    Human epidermal growth factor receptors (HER, also known as ErbB) drive cellular proliferation, pro-survival and stress responses by activating several downstream kinases, in particular ERK, p38, JNK (SAPK), the PI3K/AKT, as well as various transcriptional regulators such as STAT3. When co-expressed, first three members of HER family (HER1-3) can form homo- and hetero-dimers. Based on the considerable evidence which suggest that every receptor dimer activates intracellular signaling pathways differentially, we hypothesized that the HER dimerization pattern is a better predictor of downstream signaling than the total receptor activation levels. We validated our hypothesis using a combination of model-based analysis to quantify the HER dimerization patterns and multi-factorial experiments where HER dimerization patterns and signaling crosstalk were rationally perturbed. We have measured the activation of HER1-3 receptors and of the sentinel signaling proteins ERK, AKT, p38, JNK, STAT3 as a function of time in a panel of human mammary epithelial (HME) cells expressing different levels of HER1-3 stimulated with various ligand combinations. Our analysis using multiple ways of clustering the activation data has confirmed that the HER receptor dimer is a better predictor of the signaling through p38, ERK and AKT pathways than the total HER receptor expression and activation levels. Targeted inhibition studies to identify the causal effects allowed us to obtain a consensus regulatory interaction model, which revealed that STAT3 occupies a central role in the crosstalk between the studied pathways.

  19. Integrated analysis reveals that STAT3 is central to the crosstalk between HER/ErbB receptor signaling pathways in human mammary epithelial cells

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Gong, Chunhong; Zhang, Yi; Shankaran, Harish; Resat, Haluk

    2014-10-02

    Human epidermal growth factor receptors (HER, also known as ErbB) drive cellular proliferation, pro-survival and stress responses by activating several downstream kinases, in particular ERK, p38, JNK (SAPK), the PI3K/AKT, as well as various transcriptional regulators such as STAT3. When co-expressed, first three members of HER family (HER1-3) can form homo- and hetero-dimers. Based on the considerable evidence which suggest that every receptor dimer activates intracellular signaling pathways differentially, we hypothesized that the HER dimerization pattern is a better predictor of downstream signaling than the total receptor activation levels. We validated our hypothesis using a combination of model-based analysis tomore » quantify the HER dimerization patterns and multi-factorial experiments where HER dimerization patterns and signaling crosstalk were rationally perturbed. We have measured the activation of HER1-3 receptors and of the sentinel signaling proteins ERK, AKT, p38, JNK, STAT3 as a function of time in a panel of human mammary epithelial (HME) cells expressing different levels of HER1-3 stimulated with various ligand combinations. Our analysis using multiple ways of clustering the activation data has confirmed that the HER receptor dimer is a better predictor of the signaling through p38, ERK and AKT pathways than the total HER receptor expression and activation levels. Targeted inhibition studies to identify the causal effects allowed us to obtain a consensus regulatory interaction model, which revealed that STAT3 occupies a central role in the crosstalk between the studied pathways.« less

  20. Framework Topic Briefing: Direct Feed LAW

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    February 13, 2014 Framework Topic Briefing: Direct Feed LAW Next steps: Put Dick's handouts on SharePoint * Continue Framework topic briefing series Page 1 System Plan 7 Next ...

  1. TEC Working Group Topic Groups Routing

    Broader source: Energy.gov [DOE]

    The Routing Topic Group has been established to examine topics of interest and relevance concerning routing of shipments of spent nuclear fuel (SNF) and high-level radioactive waste (HLW) to a...

  2. Energy & Manufacturing Workforce Training Topics List - Version...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    & Manufacturing Workforce Training Topics List - Version 1.7 (02.11.14) Energy & Manufacturing Workforce Training Topics List - Version 1.7 (02.11.14) View this searchable list of ...

  3. Metabolic analysis of the soil microbe Dechloromonas aromatica str. RCB: indications of a surprisingly complex life-style and cryptic anaerobic pathways for aromatic degradation

    SciTech Connect (OSTI)

    Salinero, Kennan Kellaris; Keller, Keith; Feil, William S.; Feil, Helene; Trong, Stephan; Di Bartolo, Genevieve; Lapidus, Alla

    2008-11-17

    Initial interest in Dechloromonas aromatica strain RCB arose from its ability to anaerobically degrade benzene. It is also able to reduce perchlorate and oxidize chlorobenzoate, toluene, and xylene, creating interest in using this organism for bioremediation. Little physiological data has been published for this microbe. It is considered to be a free-living organism. The a priori prediction that the D. aromatica genome would contain previously characterized 'central' enzymes involved in anaerobic aromatic degradation proved to be false, suggesting the presence of novel anaerobic aromatic degradation pathways in this species. These missing pathways include the benzyl succinyl synthase (bssABC) genes (responsible for formate addition to toluene) and the central benzoylCoA pathway for monoaromatics. In depth analyses using existing TIGRfam, COG, and InterPro models, and the creation of de novo HMM models, indicate a highly complex lifestyle with a large number of environmental sensors and signaling pathways, including a relatively large number of GGDEF domain signal receptors and multiple quorum sensors. A number of proteins indicate interactions with an as yet unknown host, as indicated by the presence of predicted cell host remodeling enzymes, effector enzymes, hemolysin-like proteins, adhesins, NO reductase, and both type III and type VI secretory complexes. Evidence of biofilm formation including a proposed exopolysaccharide complex with the somewhat rare exosortase (epsH), is also present. Annotation described in this paper also reveals evidence for several metabolic pathways that have yet to be observed experimentally, including a sulphur oxidation (soxFCDYZAXB) gene cluster, Calvin cycle enzymes, and nitrogen fixation (including RubisCo, ribulose-phosphate 3-epimerase, and nif gene families, respectively). Analysis of the D. aromatica genome indicates there is much to be learned regarding the metabolic capabilities, and life-style, for this microbial species

  4. Density Functional Theory Calculations and Analysis of Reaction Pathways for Reduction of Nitric Oxide by Hydrogen on Pt(111)

    SciTech Connect (OSTI)

    Farberow, Carrie A.; Dumesic, James A.; Mavrikakis, Manos

    2014-10-03

    Reaction pathways are explored for low temperature (e.g., 400 K) reduction of nitric oxide by hydrogen on Pt(111). First-principles electronic structure calculations based on periodic, self-consistent density functional theory(DFT-GGA, PW91) are employed to obtain thermodynamic and kinetic parameters for proposed reaction schemes on Pt(111). The surface of Pt(111) during NO reduction by H? at low temperatures is predicted to operate at a high NO coverage, and this environment is explicitly taken into account in the DFT calculations. Maximum rate analyses are performed to assess the most likely reaction mechanisms leading to formation of N?O, the major product observed experimentally at low temperatures. The results of these analyses suggest that the reaction most likely proceeds via the addition of at least two H atoms to adsorbed NO, followed by cleavage of the N-O bond.

  5. Technical Assistance Topics | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Technical Assistance Topics Technical Assistance Topics Topics addressed are those of greatest interest to states, regions, and Tribes, including: Reliability, resiliency, and cyber security of electric power systems Electric resource planning, integrated resource planning, regional transmission planning, and resource acquisition strategies Ratepayer-funded energy efficiency, demand response, and smart grid programs Renewable energy development, including state renewable portfolio standards,

  6. Technical Assistance Topics | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Electricity Policy Coordination and Implementation » Electricity Policy Technical Assistance Program » Technical Assistance Topics Technical Assistance Topics Topics addressed are those of greatest interest to states, regions, and Tribes, including: Reliability, resiliency, and cyber security of electric power systems Electric resource planning, integrated resource planning, regional transmission planning, and resource acquisition strategies Ratepayer-funded energy efficiency, demand response,

  7. SRNL ALL-PATHWAYS APPLICATION

    SciTech Connect (OSTI)

    Koffman, L; Elmer Wilhite, E; Leonard Collard, L

    2007-05-29

    The Environmental Analysis and Performance Modeling group of Savannah River National Laboratory (SRNL) performs performance assessments of the Savannah River Site (SRS) low-level waste facilities to meet the requirements of DOE Order 435.1. One of the performance objectives in the DOE Order is that the radiological dose to representative members of the public shall not exceed 25 mrem in a year total effective dose equivalent from all exposure pathways, excluding radon. Analysis to meet this performance objective is generally referred to as all-pathways analysis. SRNL performs detailed transient groundwater transport analysis for the waste disposal units, which has been used as input for the groundwater part of all-pathways analysis. The desire to better integrate all-pathways analysis with the groundwater transport analysis lead to the development of a software application named the SRNL All-Pathways Application. Another requirement of DOE Order 435.1 is to assess the impact of nuclear waste disposal on water resources, which SRS has interpreted for groundwater protection as meeting the EPA regulations for radionuclides in drinking water. EPA specifies four separate criteria as part of their implementation guidance for radionuclides, which are specified as maximum contaminant levels (MCL). (1) Beta/gamma emitters have a combined dose limit of 4 mrem/year. (2) Alpha emitters have a combined concentration limit of 15 pCi/L (called gross alpha), excluding uranium and radon, but including radium-226. (3) Combined radium-226 and radium-228 have a concentration limit of 5 pCi/L. (4) Isotopes of uranium have a combined concentration limit of 30 {micro}g/L. The All-Pathways Application was designed to be an easy-to-use software application that utilizes transient concentration results from groundwater transport analysis to (1) calculate the groundwater part of all-pathways dose and to (2) evaluate the four EPA criteria for groundwater protection.

  8. Engineering ESPT Pathways Based on Structural Analysis of LSSmKate Red Fluorescent Proteins with Large Stokes Shift

    SciTech Connect (OSTI)

    Piatkevich, K.; Malashkevich, V; Almo, S; Verkhusha, V

    2010-01-01

    LSSmKate1 and LSSmKate2 are monomeric red fluorescent proteins (RFPs) with large Stokes shifts (LSSs), which allows for efficient separation of absorbance and emission maxima, as well as for excitation with conventional two-photon laser sources. These LSSmKates differ by a single amino acid substitution at position 160 and exhibit absorbance maxima around 460 nm, corresponding to a neutral DsRed-like chromophore. However, excitation at 460 nm leads to fluorescence emission above 600 nm. Structures of LSSmKate1 and LSSmKate2, determined at resolutions of 2.0 and 1.5 {angstrom}, respectively, revealed that the predominant DsRed-chromophore configurations are cis for LSSmKate1 but trans for LSSmKate2. Crystallographic and mutagenesis analyses, as well as isotope and temperature dependences, suggest that an excited-state proton transfer (ESPT) is responsible for the LSSs observed in LSSmKates. Hydrogen bonding between the chromophore hydroxyl and Glu160 in LSSmKate1 and a proton relay involving the chromophore tyrosine hydroxyl, Ser158, and the Asp160 carboxylate in LSSmKate2 represent the putative ESPT pathways. Comparisons with mKeima LSS RFP suggest that similar proton relays could be engineered in other FPs. Accordingly, we mutated positions 158 and 160 in several conventional red-shifted FPs, including mNeptune, mCherry, mStrawberry, mOrange, and mKO, and the resulting FP variants exhibited LSS fluorescence emission in a wide range of wavelengths from 560 to 640 nm. These data suggest that different chromophores formed by distinct tripeptides in different environments can be rationally modified to yield RFPs with novel photochemical properties.

  9. Fuel Pathways Integration Tech Team | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Pathways Integration Tech Team Fuel Pathways Integration Tech Team Presentation on Fuel Pathways Integration Tech Team to the DOE Systems Analysis Workshop held in Washington, D.C. July 28-29, 2004. 8_fpitt_gardner.pdf (109.24 KB) More Documents & Publications Systems Analysis Workshop Agenda Hydrogen Analysis Analysis Activities at National Renewable Energy Laboratory

  10. Pathways and transformations of dissolved methane and dissolved inorganic carbon in Arctic tundra watersheds: Evidence from analysis of stable isotopes

    SciTech Connect (OSTI)

    Throckmorton, Heather M.; Heikoop, Jeffrey M.; Newman, Brent D.; Altmann, Garrett L.; Conrad, Mark S.; Muss, Jordan D.; Perkins, George B.; Smith, Lydia J.; Torn, Margaret S.; Wullschleger, Stan D.; Wilson, Cathy J.

    2015-11-08

    Arctic soils contain a large pool of terrestrial C and are of interest due to their potential for releasing significant carbon dioxide (CO2) and methane (CH4) to the atmosphere. Due to substantial landscape heterogeneity, predicting ecosystem-scale CH4 and CO2 production is challenging. This study assessed dissolved inorganic carbon (DIC = Σ (total) dissolved CO2) and CH4 in watershed drainages in Barrow, Alaska as critical convergent zones of regional geochemistry, substrates, and nutrients. In July and September of 2013, surface waters and saturated subsurface pore waters were collected from 17 drainages. Based on simultaneous DIC and CH4 cycling, we synthesized isotopic and geochemical methods to develop a subsurface CH4 and DIC balance by estimating mechanisms of CH4 and DIC production and transport pathways and oxidation of subsurface CH4. We observed a shift from acetoclastic (July) toward hydrogenotropic (September) methanogenesis at sites located toward the end of major freshwater drainages, adjacent to salty estuarine waters, suggesting an interesting landscape-scale effect on CH4 production mechanism. The majority of subsurface CH4 was transported upward by plant-mediated transport and ebullition, predominantly bypassing the potential for CH4 oxidation. Thus, surprisingly, CH4 oxidation only consumed approximately 2.51± 0.82% (July) and 0.79 ± 0.79% (September) of CH4 produced at the frost table, contributing to <0.1% of DIC production. DIC was primarily produced from respiration, with iron and organic matter serving as likely e- acceptors. Furthermore, this work highlights the importance of spatial and temporal variability of CH4 production at the watershed scale and suggests broad scale investigations are required to build better regional or pan-Arctic representations of CH

  11. Physics Topics - MST - UW Plasma Physics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Physics Topics UW Madison Madison Symmetric Torus Physics Topics MST HomeGraduate Student InformationLinksTourControl and Auxiliary SystemsPhysics TopicsDeviceResearch MissionMST People mst logo CPLA Home Directory Publications Links Internal University of Wisconsin Physics Department Research funding includes support from: Department of Energy National Science Foundation The MST physics challenges are large and many, but much of our work is captured in the following four major RFP physics goals

  12. LANSCE | Users | LUG | Topical User Workshop

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    2 LANSCE Topical User Meeting | January 9-10 2012 LANSCE Topical User Workshop LANSCE will host the 2012 Topical User Workshop, January 9-10, 2012. We hope to see you there! Registration | Accommodations | Agenda (some presentations are included on the agenda) LANL foreign nationals may register at anytime. | Poster Dimensions: 32 in x 40 in This workshop will solicit user input for the scientific opportunities offered by the pulse stacker and superconducting accelerator that LANSCE has proposed

  13. Preface: Special Topic on Interfacial and Confined Water (Journal...

    Office of Scientific and Technical Information (OSTI)

    Preface: Special Topic on Interfacial and Confined Water Citation Details In-Document Search Title: Preface: Special Topic on Interfacial and Confined Water This Special Topic on...

  14. Topic Index to the DOE Administrative Records Disposition Schedules...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Topic Index to the DOE Administrative Records Disposition Schedules Topic Index to the DOE Administrative Records Disposition Schedules Topic Index to the DOE Administrative...

  15. Interconnection-Wide Transmission Planning Initiative: Topic...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Western Interconnection on Electric Resource Planning and Priorities Interconnection-Wide Transmission Planning Initiative: Topic B, Cooperation Among States in the Western ...

  16. Interconnection-Wide Transmission Planning Initiative: Topic...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Eastern Interconnection on Electric Resource Planning and Priorities Interconnection-Wide Transmission Planning Initiative: Topic B, Cooperation Among States in the Eastern ...

  17. Interconnection-Wide Transmission Planning Initiative: Topic...

    Energy Savers [EERE]

    the Texas Interconnection Interconnection-Wide Transmission Planning Initiative: Topic B, State Agency Input Regarding Electric Resource and Transmission Planning in the Texas ...

  18. TEC Working Group Topic Groups Rail Conference Call Summaries...

    Office of Environmental Management (EM)

    Summaries Rail Topic Group TEC Working Group Topic Groups Rail Conference Call Summaries Rail Topic Group Rail Topic Group PDF icon May 17, 2007 PDF icon January 16, 2007 PDF icon...

  19. Webtrends Archives by Fiscal Year - Topic Landing Pages | Department...

    Broader source: Energy.gov (indexed) [DOE]

    topic landing pages by fiscal year. Topic Landing Pages FY10 (2.04 MB) Topic Landing Pages FY11 (2.02 MB) Topic Landing Pages FY12-FY13 (366.66 KB) More Documents & Publications ...

  20. What are pathways?

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    body. For the inhalation or airborne pathway, a material is inhaled directly into the lungs and then moves into the bloodstream. For the ingestion pathway, there are several...

  1. Analysis of Potential Leakage Pathways and Mineralization within Caprocks for Geologic Storage of CO2

    SciTech Connect (OSTI)

    Evans, James

    2013-05-01

    normal faults in the Permian Cedar Mesa Sandstone, southeastern Utah. These faults are characterized by a single slip surfaces and damage zones containing deformation bands, veins, and joints. Field observations include crosscutting relationships, permeability increase, rock strength decrease, and ultraviolet light induced mineral fluorescence within the damage zone. These field observations combined with the interpreted paragenetic sequence from petrographic analysis, suggests a deformation history of reactivation and several mineralization events in an otherwise low-permeability fault. All deformation bands and veins fluoresce under ultraviolet light, suggesting connectivity and a shared mineralization history. Pre-­existing deformation features act as loci for younger deformation and mineralization events, this fault and its damage zone illustrate the importance of the fault damage zone to subsurface fluid flow. We model a simplified stress history in order to understand the importance of rock properties and magnitude of tectonic stress on the deformation features within the damage zone. The moderate confining pressures, possible variations in pore pressure, and the porous, fine-­grained nature of the Cedar Mesa Sandstone results in a fault damage zone characterized by enhanced permeability, subsurface fluid flow, and mineralization. Structural setting greatly influences fracture spacing and orientation. Three structural settings were examined and include fault proximity, a fold limb of constant dip, and a setting proximal to the syncline hinge. Fracture spacing and dominant fracture orientation vary at each setting and distinctions between regional and local paleo-stress directions can be made. Joints on the fold limb strike normal to the fold axis/bedding and are interpreted to be sub-parallel to the maximum regional paleo-stress direction as there is no fold related strain. Joints proximal to faults and the syncline hinge may have formed under local stress

  2. Jonathan Link, Columbia KEK Topical Conference

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    -22, 2001 Jonathan Link, Columbia KEK Topical Conference Short Baseline Neutrino Oscillations and MiniBooNE Jonathan Link Columbia University The 5 th KEK Topical Conference - Frontiers in Flavor Physics November 20-22, 2001 November 20-22, 2001 Jonathan Link, Columbia KEK Topical Conference Outline 1. Background on Short Baseline Neutrino Oscillations * A little neutrino physics * The LSND oscillation result 2. About MiniBooNE 3. Status of MiniBooNE. Some of you may have noticed that I'll be

  3. TEC/WG Tribal Topic Group

    Office of Environmental Management (EM)

    TEC Tribal Topic Group Conference Call January 18, 2006 Group Chair: Jay Jones (DOE/OCRWM) Participating TEC Tribal Topic Group Members: Rob Burnside (CTUIR), Earl Easton (U.S. NRC), Kristen Ellis (DOE/CI), Ed Gonzales (ELG), Angela Hill (DOE/OCRWM), Marsha Keister (INL), Dan King (Oneida Nation), Corinne Macaluso (DOE/OCRWM), Titto Moses (CTUIR), Stanley Paytiamo (Pueblo of Acoma), Willie Preacher (Shoshone-Bannock Tribes), Cathy Reynolds (DOE/GC), Larry Stern (CVSA), Kevin Tafoya (Santa Clara

  4. TEC Working Group Topic Groups Rail Key Documents Intermodal Subgroup |

    Office of Environmental Management (EM)

    Department of Energy Intermodal Subgroup TEC Working Group Topic Groups Rail Key Documents Intermodal Subgroup Intermodal Subgroup Draft Work Plan (206.83 KB) More Documents & Publications TEC Working Group Topic Groups Rail Key Documents Radiation Monitoring Subgroup TEC Working Group Topic Groups Rail Conference Call Summaries Intermodal Subgroup TEC Working Group Topic Groups Rail Conference Call Summaries Rail Topic Group

  5. TEC Working Group Topic Groups Routing Meeting Summaries | Department of

    Office of Environmental Management (EM)

    Energy Meeting Summaries TEC Working Group Topic Groups Routing Meeting Summaries MEETING SUMMARIES Atlanta TEC Meeting, Routing Topic Group Summary (101.72 KB) More Documents & Publications TEC Meeting Summaries - January - February 2007 TEC Working Group Topic Groups Rail Meeting Summaries TEC Working Group Topic Groups Rail Conference Call Summaries Rail Topic Group

  6. Hydrogen Pathway Cost Distributions

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Pathway Cost Distributions Jim Uihlein Fuel Pathways Integration Tech Team January 25, 2006 2 Outline * Pathway-Independent Cost Goal * Cost Distribution Objective * Overview * H2A Influence * Approach * Implementation * Results * Discussion Process * Summary 3 Hydrogen R&D Cost Goal * Goal is pathway independent * Developed through a well defined, transparent process * Consumer fueling costs are equivalent or less on a cents per mile basis * Evolved gasoline ICE and gasoline-electric

  7. OSTIblog Articles in the history of science Topic | OSTI, US...

    Office of Scientific and Technical Information (OSTI)

    history of science Topic World Wide Information: The Other Side of the Coin by Kristin ... Of course, the world's information covers numerous topics other than science and ...

  8. Events & Topics in Renewable Energy & the Environment | Photosynthetic...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Events & Topics in Renewable Energy & the Environment Events & Topics in Renewable Energy & the Environment MIssouri Botanical Garden | Earthways Center - October 6th, 3:15 -...

  9. Public Perception of 13 Different Energy Topics analyzed in new...

    Open Energy Info (EERE)

    and unfavorability energy topics such as transportation, renewable technology, nuclear, clean coal, and smart grid topics. Some of the highlights of the study are as...

  10. TEC Working Group Topic Groups Security | Department of Energy

    Office of Environmental Management (EM)

    TEC Working Group Topic Groups Security The Security Topic group is comprised of regulators, law enforcement officials, labor and industry representatives and other subject matter ...

  11. Events & Topics in Renewable Energy & the Environment | Photosynthetic...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Events & Topics in Renewable Energy & the Environment Events & Topics in Renewable Energy & the Environment Tyson Living Learning Center tour November 18, 2014 - 4:00pm Tyson...

  12. Events & Topics in Renewable Energy & the Environment | Photosynthetic...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Events & Topics in Renewable Energy & the Environment Events & Topics in Renewable Energy & the Environment Donald Danforth Plant Science Center April 9, 2015 - 3:15pm Donald...

  13. Hot Topics Workshops | June 2016 | Photosynthetic Antenna Research Center

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Workshops | June 2016 Hot Topics Workshops | June 2016 A look at our workshops this past June on various topics including nuclear energy, biofuels, and renewable

  14. TEC Working Group Topic Groups Rail Meeting Summaries | Department...

    Office of Environmental Management (EM)

    TEC Working Group Topic Groups Rail Meeting Summaries MEETING SUMMARIES PDF icon Kansas City TEC Meeting, Rail Topic Group Summary - July 25, 2007 PDF icon Atlanta TEC...

  15. OSTIblog Articles in the greenhouse gases Topic | OSTI, US Dept...

    Office of Scientific and Technical Information (OSTI)

    greenhouse gases Topic Carbon Sequestration - Helping to Save Our Beautiful World by Kathy ... Related Topics: carbon dioxide, carbon sequestration, climate change, greenhouse gases

  16. Hot topics in flavor physics at CDF

    SciTech Connect (OSTI)

    Jun, Soon Yung; /Carnegie Mellon U.

    2005-01-01

    Hot topics in flavor physics at CDF are reviewed. Selected results of top, beauty, charm physics and exotic states in about 200 pb{sup -1} data collected by the CDF II detector in p{bar p} collisions at {radical}s = 1.96 TeV at the Fermilab Tevatron are presented.

  17. Quark-gluon plasma (Selected Topics)

    SciTech Connect (OSTI)

    Zakharov, V. I.

    2012-09-15

    Introductory lectures to the theory of (strongly interacting) quark-gluon plasma given at the Winter School of Physics of ITEP (Moscow, February 2010). We emphasize theoretical issues highlighted by the discovery of the low viscosity of the plasma. The topics include relativistic hydrodynamics, manifestations of chiral anomaly in hydrodynamics, superfluidity, relativistic superfluid hydrodynamics, effective stringy scalars, holographic models of Yang-Mills theories.

  18. Pathway and Resource Overview | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    and Resource Overview Pathway and Resource Overview Presented at the Renewable Hydrogen Workshop, Nov. 16, 2009, in Palm Springs, CA renewable_hydrogen_workshop_nov16_ruth.pdf (684.83 KB) More Documents & Publications US DOE Hydrgoen Program- HyDRA (Hydrogen Demand and Resource Analysis Tool Hydrogen Pathways: Cost, Well-to-Wheels Energy Use, and Emissions for the Current Technology Status of Seven Hydrogen Production, Delivery, and Distribution Scenarios Analysis Models and Tools: Systems

  19. Regulatory cross-cutting topics for fuel cycle facilities.

    SciTech Connect (OSTI)

    Denman, Matthew R.; Brown, Jason; Goldmann, Andrew Scott; Louie, David

    2013-10-01

    This report overviews crosscutting regulatory topics for nuclear fuel cycle facilities for use in the Fuel Cycle Research&Development Nuclear Fuel Cycle Evaluation and Screening study. In particular, the regulatory infrastructure and analysis capability is assessed for the following topical areas:Fire Regulations (i.e., how applicable are current Nuclear Regulatory Commission (NRC) and/or International Atomic Energy Agency (IAEA) fire regulations to advance fuel cycle facilities)Consequence Assessment (i.e., how applicable are current radionuclide transportation tools to support risk-informed regulations and Level 2 and/or 3 PRA) While not addressed in detail, the following regulatory topic is also discussed:Integrated Security, Safeguard and Safety Requirement (i.e., how applicable are current Nuclear Regulatory Commission (NRC) regulations to future fuel cycle facilities which will likely be required to balance the sometimes conflicting Material Accountability, Security, and Safety requirements.)

  20. TEC Working Group Topic Groups Archives | Department of Energy

    Office of Environmental Management (EM)

    Archives TEC Working Group Topic Groups Archives The following Topic Groups are no longer active; however, related documents and notes for these archived Topic Groups are available through the following links: Communications Consolidated Grant Topic Group Training - Medical Training Protocols Route Identification Process Mechanics of Funding and Technical Assistance

  1. Innovative Topics for Advanced Biofuels | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Innovative Topics for Advanced Biofuels Innovative Topics for Advanced Biofuels PNNL report-out presentation at the CTAB webinar on innovative topics for advanced biofuels. ctab_webinar_innovative_topics.pdf (1.55 MB) More Documents & Publications Cross-cutting Technologies for Advanced Biofuels Conversion Technologies for Advanced Biofuels - Carbohydrates Production Conversion Technologies for Advanced Biofuels - Bio-Oil Upgrading

  2. Technology Pathway Selection Effort

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    BIOMASS PROGRAM Technology Pathway Selection Effort Alicia Lindauer 27 November 2012 2 | Biomass Program eere.energy.gov * Setting R&D priorities * Benchmarking * Informing multi-sectoral analytical activities * Track Program R&D progress against goals * Identify technology process routes and prioritize funding * Program direction decisions: * Are we spending our money on the right technology pathways? * Within a pathway: Are we focusing our funding on the highest priority activities?

  3. Topic A Awardee: Eastern Interconnection Planning Collaborative |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Eastern Interconnection Planning Collaborative Topic A Awardee: Eastern Interconnection Planning Collaborative Eastern Interconnection Planning Collaborative The Eastern Interconnection Planning Collaborative (EIPC) was initiated by a coalition of regional Planning Authorities. These Planning Authorities are entities listed on the NERC compliance registry as Planning Authorities and represent the entire Eastern Interconnection. The EIPC was founded to be a broad-based,

  4. Renewable Energy Project Development: Advanced Concept Topics

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Concept Topics An Introduction to Risk, Tribal Roles, and Support Policies in the Renewable Energy Project Development Process Course Outline What we will cover...  About the DOE Office of Indian Energy Education Initiative  Concepts and Policies for Understanding Renewable Energy Projects on Tribal Lands - Risk and Uncertainty - Tribal Project Roles - Policies and Incentives  Additional Information and Resources 2 Introduction The U.S. Department of Energy (DOE) Office of Indian Energy

  5. Renewable Energy Project Development: Advanced Process Topics

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Process Topics Understanding Energy Markets, Project Scale Decision Factors, Procurement Options, and the Role of the Project Team Course Outline What we will cover...  About the DOE Office of Indian Energy Education Initiative  Processes for Developing Renewable Energy Projects on Tribal Lands - Understanding the Energy Market and Project Scale - Project Scale and Ownership Options - Procurement Process - Project Team  Additional Information and Resources 2 Introduction The U.S.

  6. TEC/WG Tribal Topic Group

    Office of Environmental Management (EM)

    Meeting September 22, 2005 - Pueblo, CO Group Chair: Jay Jones (DOE/OCRWM) Tribal Topic Group Members Present: Richard Arnold (Southern Paiute/CGTO), Vicki Best (Bechtel SAIC-YMP), Kevin Blackwell (DOT/FRA), Sandra Covi (UPRR), Barbara Durham (Timbisha Shoshone Tribe), Greg Fasano (Bechtel SAIC-YMP), Elizabeth Helvey (BSC), Angela Hill (DOE/OCRWM), Judith Holm (DOE/OCRWM), Marsha Keister (INL), Dan King (Oneida Nation), Gary Lanthrum (DOE/OCRWM), Corinne Macaluso (DOE/OCRWM), Calvin Meyers

  7. TEC/WG Tribal Topic Group

    Office of Environmental Management (EM)

    Conference Call December 6, 2005 Group Chair: Jay Jones (DOE/OCRWM) Participating TEC Tribal Topic Group Members: Kevin Clarke (DOE/RL), Kristen Ellis (DOE/CI), Lisa Gover (NTEC), Dan King (Oneida Nation), Corinne Macaluso (DOE/OCRWM), Ellen Ott (DOE/GC), Ted Repasky (CTUIR), Cathy Reynolds (DOE/GC), Lisa Sattler (CSG-MW) Herman Shorty (Navajo Nation), Linda Sikkema (NCSL), Christopher Wells (SSEB) DOE support contractors also participated in this call. Action Items: Responsible Party Action to

  8. TEC Working Group Topic Groups Rail Conference Call Summaries Rail Topic

    Office of Environmental Management (EM)

    Group | Department of Energy Summaries Rail Topic Group TEC Working Group Topic Groups Rail Conference Call Summaries Rail Topic Group Rail Topic Group May 17, 2007 (10.98 KB) January 16, 2007 (14.41 KB) August 31, 2006 (16.39 KB) July 27, 2006 (19.28 KB) June 8, 2006 (15.79 KB) April 20, 2006 (19.91 KB) March 9, 2006 (19.65 KB) January 26, 2006 (20.86 KB) November 9, 2005 (24.38 KB) September 15, 2005 (32.13 KB) April 28, 2005 (19.16 KB) March 24, 2005 (28.33 KB) February 24, 2005 (32.77

  9. Proceedings of the 1992 topical meeting on advances in reactor physics. Volume 2

    SciTech Connect (OSTI)

    Not Available

    1992-04-01

    This document, Volume 2, presents proceedings of the 1992 Topical Meeting on Advances in Reactor Physics on March 8--11, 1992 at Charleston, SC. Session topics were as follows: Transport Theory; Fast Reactors; Plant Analyzers; Integral Experiments/Measurements & Analysis; Core Computational Systems; Reactor Physics; Monte Carlo; Safety Aspects of Heavy Water Reactors; and Space-Time Core Kinetics. The individual reports have been cataloged separately. (FI)

  10. TEC Working Group Topic Groups | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Topic Groups TEC Working Group Topic Groups TEC Topic Groups were formed in 1991 following an evaluation of the TEC program. Interested members, DOE and other federal agency staff meet to examine specific issues related to radioactive materials transportation. TEC Topic Groups enable a small number of participants to focus intensively on key issues at a level of detail that is unattainable during the TEC semiannual meetings due to time and group size constraints. Topic Groups meet individually

  11. Direct injection of natural gas in blast furnaces at high rates: Preliminary statistical analysis of blast furnace carbon balance at Armco-Middletown. Topical report, January 1990-September 1992

    SciTech Connect (OSTI)

    Neels, J.K.; Brown, F.C.

    1992-09-01

    The economic benefits of supplemental fuel injections depend, in part, on the coke replacement ratio. An assessment of the accuracy with which blast furnace coke rate may be measured and a determination of the key drivers of coke rate uncertainty are offered, to provide guidance for experiments in high-rate gas injection. Using statistical analysis tools, an expression for the measurement error associated with the various terms of blast furnace carbon balance is developed. Coke rate calculations based on the material balance are most sensitive to coke carbon content and to proper tracking of hot metal tapping schedule.

  12. Preface to Special Topic: Marine Renewable Energy

    SciTech Connect (OSTI)

    Pinto, F. T.; Iglesias, G.; Santos, P. R.; Deng, Zhiqun

    2015-12-30

    Marine renewable energy (MRE) is generates from waves, currents, tides, and thermal resources in the ocean. MRE has been identified as a potential commercial-scale source of renewable energy. This special topic presents a compilation of works selected from the 3rd IAHR Europe Congress, held in Porto, Portugal, in 2014. It covers different subjects relevant to MRE, including resource assessment, marine energy sector policies, energy source comparisons based on levelized cost, proof-of-concept and new-technology development for wave and tidal energy exploitation, and assessment of possible inference between wave energy converters (WEC).

  13. TEC/WG Tribal Topic Group

    Office of Environmental Management (EM)

    April 4, 2005 - Phoenix, AZ Group Chair: Jay Jones (DOE/OCRWM) Tribal Topic Group Members Present: Nancy Bennett (UNM/ATRI), Kevin Blackwell (DOT/FRA), Kristen Ellis (DOE/CI), Ed Gonzales (ELG), Elizabeth Helvey (BSC), Jeff Hepting (Pueblo of Acoma), Robert Holden (NCAI), Judith Holm (DOE/OCRWM), Dan King (Oneida Nation), Gary Lanthrum (DOE/OCRWM), Bob Lupton (DOE/ORD/IR), Corinne Macaluso (DOE/OCRWM), Ellen Ott (DOE/GC), Jennifer Patric (BAH), Stanley Paytiamo (Pueblo of Acoma), Wilda Portner

  14. Sustainability & Strategic Analysis

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... Technologies Office * Design cases of biofuel pathways * Environmental sustainability metrics for conversion stage * GREET analysis of full pathway to identify drivers of GHG ...

  15. Solar Market Pathways

    Broader source: Energy.gov [DOE]

    The Solar Market Pathways website distributes key insights from 15 SunShot Initiative projects that are advancing solar deployment across the United States. These projects take a variety of...

  16. OSTIblog Articles in the science information Topic | OSTI, US...

    Office of Scientific and Technical Information (OSTI)

    The search engine that helps you find science information from U.S. Department of Energy ... Science News and Wikipedia information on your topic(s) of interest and clusters results ...

  17. Events & Topics in Renewable Energy & the Environment | Photosynthetic...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Events & Topics in Renewable Energy & the Environment Events & Topics in Renewable Energy & the Environment Missouri Botanical Garden- EarthWays Center October 6, 2015 - 4:00pm How...

  18. Hot Topics Workshop - February 2015 | Photosynthetic Antenna Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Center - February 2015 Hot Topics Workshop - February 2015 Shots from our Hot Topics Workshop: Energy and the Environment for Secondary Science Teachers. Original Event Info found here

  19. TEC Working Group Topic Groups Rail Conference Call Summaries | Department

    Office of Environmental Management (EM)

    of Energy Rail Conference Call Summaries TEC Working Group Topic Groups Rail Conference Call Summaries CONFERENCE CALL SUMMARIES Rail Topic Group Inspections Subgroup Planning Subgroup Tracking Subgroup TRAGIS Subgroup Radiation Monitoring Subgroup Intermodel Subgroup

  20. Assessing Pathways in Aruba

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    2: Assessing Opportunity Pathways Assessing Pathways in Aruba In 2010, Prime Minister Eman of Aruba expressed an ambitious goal: to transition Aruba to 100% renew- able energy by 2020. Aruba offers a valuable example of how to approach vision and goal setting for an energy project or initiative. Challenge Strong tourism and growth in the hospitality industry are boosting economic development for the island of Aruba. However, like many islands and remote locations, Aruba must import thousands of

  1. Smart Grid Investment Grant Topic Areas | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Topic Areas Smart Grid Investment Grant Topic Areas A description of the topic areas for projects selected for award under the Smart Grid Investment Grant project of the American Recovery and Reinvestment Act. Smart Grid Investment Grant Topic Areas (25.19 KB) More Documents & Publications Smart Grid Investment Grant Program - Progress Report (July 2012) SGIG and SGDP Highlights: Jumpstarting a Modern Grid (October 2014) Smart Grid R&D Multi-Year Program Plan (2010-2014) - September 2011

  2. OSTIblog Articles in the Strategic Plan Topic | OSTI, US Dept...

    Office of Scientific and Technical Information (OSTI)

    and nuclear challenges through transformative science and technology solutions. The... Related Topics: clean energy, nuclear security, Science Accelerator, Strategic Plan

  3. TEC Working Group Topic Groups Archives Communications Meeting Summaries |

    Office of Environmental Management (EM)

    Department of Energy Archives Communications Meeting Summaries TEC Working Group Topic Groups Archives Communications Meeting Summaries Meeting Summaries Milwaukee TEC Meeting, Communications Topic Group Summary - July 1998 (58.3 KB) Inaugural Group Meeting - April 1998 (83.34 KB) More Documents & Publications TEC Working Group Topic Groups Archives Communications Conference Call Summaries TEC Meeting Summaries - January 1997 TEC Working Group Topic Groups Tribal Conference Call

  4. Webtrends Archives by Fiscal Year — Topic Landing Pages

    Broader source: Energy.gov [DOE]

    From the EERE Web Statistics Archive: Corporate sites, Webtrends archives for the topic landing pages by fiscal year.

  5. TEC Working Group Topic Groups Archives Protocols Meeting Summaries |

    Office of Environmental Management (EM)

    Department of Energy Protocols Meeting Summaries TEC Working Group Topic Groups Archives Protocols Meeting Summaries Meeting Summaries Philadelphia TEC Meeting, Protocols Topic Group Summary - July 1999 (110.63 KB) Jacksonville TEC Meeting, Protocols Topic Group Summary - January 1999 (102.04 KB) More Documents & Publications TEC Working Group Topic Groups Archives Protocols Conference Call Summaries TEC Meeting Summaries - July 1997 TEC Meeting Summaries - January 1997

  6. TEC Working Group Topic Groups Rail Conference Call Summaries Inspections

    Office of Environmental Management (EM)

    Subgroup | Department of Energy Summaries Inspections Subgroup TEC Working Group Topic Groups Rail Conference Call Summaries Inspections Subgroup Inspections Subgroup April 6, 2006 (14.05 KB) February 23, 2006 Draft (20.29 KB) January 24, 2006 (27.44 KB) More Documents & Publications TEC Working Group Topic Groups Rail Conference Call Summaries Planning Subgroup TEC Working Group Topic Groups Rail Conference Call Summaries Tracking Subgroup TEC Working Group Topic Groups Rail Conference

  7. TEC Working Group Topic Groups Rail Key Documents Radiation Monitoring

    Office of Environmental Management (EM)

    Subgroup | Department of Energy Radiation Monitoring Subgroup TEC Working Group Topic Groups Rail Key Documents Radiation Monitoring Subgroup Radiation Monitoring Subgroup Draft Work Plan - February 4, 2008 (114.02 KB) More Documents & Publications TEC Working Group Topic Groups Rail Meeting Summaries TEC Working Group Topic Groups Rail Conference Call Summaries Radiation Monitoring Subgroup TEC Working Group Topic Groups Rail Key Documents Intermodal Subgroup

  8. OSTIblog Articles in the 9 Topic | OSTI, US Dept of Energy Office of

    Office of Scientific and Technical Information (OSTI)

    Scientific and Technical Information 9 Topic No topics or articles found

  9. TEC Working Group Topic Groups Archives Protocols | Department of Energy

    Office of Environmental Management (EM)

    Protocols TEC Working Group Topic Groups Archives Protocols The Transportation Protocols Topic Group serves as an important vehicle for DOE senior managers to assess and incorporate stakeholder input into the protocols process. The Topic Group was formed to review a series of transportation protocols developed in response to a request for DOE to be more consistent in its approach to transportation.

  10. TEC Working Group Topic Groups Section 180(c) Meeting Summaries |

    Office of Environmental Management (EM)

    Department of Energy Section 180(c) Meeting Summaries TEC Working Group Topic Groups Section 180(c) Meeting Summaries Meeting Summaries Washington, DC TEC Meeting - 180(c) Group Summary - March 15, 2006 (29.33 KB) More Documents & Publications TEC Working Group Topic Groups Tribal Meeting Summaries TEC Meeting Summaries - July 2007 TEC Working Group Topic Groups Tribal Conference Call Summaries

  11. Program Design Analysis using BEopt Building Energy Optimization Software: Defining a Technology Pathway Leading to New Homes with Zero Peak Cooling Demand; Preprint

    SciTech Connect (OSTI)

    Anderson, R.; Christensen, C.; Horowitz, S.

    2006-08-01

    An optimization method based on the evaluation of a broad range of different combinations of specific energy efficiency and renewable-energy options is used to determine the least-cost pathway to the development of new homes with zero peak cooling demand. The optimization approach conducts a sequential search of a large number of possible option combinations and uses the most cost-effective alternatives to generate a least-cost curve to achieve home-performance levels ranging from a Title 24-compliant home to a home that uses zero net source energy on an annual basis. By evaluating peak cooling load reductions on the least-cost curve, it is then possible to determine the most cost-effective combination of energy efficiency and renewable-energy options that both maximize annual energy savings and minimize peak-cooling demand.

  12. Southeast European Regional Electricity Market Analysis | Open...

    Open Energy Info (EERE)

    National Laboratory Partner United States Agency for International Development, Montgomery Watson Harza Sector Energy Topics Market analysis, Background analysis Website...

  13. Topic Area 2: Data Gathering and Analysis | Open Energy Information

    Open Energy Info (EERE)

    es":,"rectangles":,"locations":"text":"

  14. Search tool plug-in: imploements latent topic feedback

    Energy Science and Technology Software Center (OSTI)

    2011-09-23

    IRIS is a search tool plug-in that is used to implement latent topic feedback for enhancing text navigation. It accepts a list of returned documents from an information retrieval wywtem that is generated from keyword search queries. Data is pulled directly from a topic information database and processed by IRIS to determine the most prominent and relevant topics, along with topic-ngrams, associated with the list of returned documents. User selected topics are then used tomore » expand the query and presumabley refine the search results.« less

  15. Pathways, Networks and Systems Medicine Conferences

    SciTech Connect (OSTI)

    Nadeau, Joseph H.

    2013-11-25

    The 6th Pathways, Networks and Systems Medicine Conference was held at the Minoa Palace Conference Center, Chania, Crete, Greece (16-21 June 2008). The Organizing Committee was composed of Joe Nadeau (CWRU, Cleveland), Rudi Balling (German Research Centre, Brauschweig), David Galas (Institute for Systems Biology, Seattle), Lee Hood (Institute for Systems Biology, Seattle), Diane Isonaka (Seattle), Fotis Kafatos (Imperial College, London), John Lambris (Univ. Pennsylvania, Philadelphia),Harris Lewin (Univ. of Indiana, Urbana-Champaign), Edison Liu (Genome Institute of Singapore, Singapore), and Shankar Subramaniam (Univ. California, San Diego). A total of 101 individuals from 21 countries participated in the conference: USA (48), Canada (5), France (5), Austria (4), Germany (3), Italy (3), UK (3), Greece (2), New Zealand (2), Singapore (2), Argentina (1), Australia (1), Cuba (1), Denmark (1), Japan (1), Mexico (1), Netherlands (1), Spain (1), Sweden (1), Switzerland (1). With respect to speakers, 29 were established faculty members and 13 were graduate students or postdoctoral fellows. With respect to gender representation, among speakers, 13 were female and 28 were male, and among all participants 43 were female and 58 were male. Program these included the following topics: Cancer Pathways and Networks (Day 1), Metabolic Disease Networks (Day 2), Day 3 ? Organs, Pathways and Stem Cells (Day 3), and Day 4 ? Inflammation, Immunity, Microbes and the Environment (Day 4). Proceedings of the Conference were not published.

  16. Topic B Awardee: Western Governors' Association | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    -- to provide input in regional transmission planning and analysis in the interconnection. ... SPSC member list, correspondence and chronology of actions CONTACT INFORMATION Doug Larson ...

  17. Property:ProgramTopics | Open Energy Information

    Open Energy Info (EERE)

    Policy Design + Implementation +, Policiesdeployment programs + A Report on Worldwide Hydrogen Bus Demonstrations, 2002-2007 + Analysis Tools + A Review of HOV Lane Performance...

  18. Collaboration Topics - Visualization | National Nuclear Security...

    National Nuclear Security Administration (NNSA)

    This collaboration area focuses on visualization and data analysis and centers on the open ... and analyzing data on advanced architectures that are memory and IO constrained. ...

  19. Application of lidar to current atmospheric topics

    SciTech Connect (OSTI)

    Sedlacek, A.J. III

    1996-12-31

    The goal of the conference was to address the various applications of lidar to topics of interest in the atmospheric community. Specifically, with the development of frequency-agile, all solid state laser systems, high-quantum-efficiency detectors, increased computational power along with new and more powerful algorithms, and novel detection schemes, the application of lidar to both old and new problems has expanded. This expansion is evidenced by the contributions to the proceedings, which demonstrate the progress made on a variety of atmospheric remote sensing problems, both theoretically and experimentally. The first session focused on aerosol, ozone, and temperature profile measurements from ground-based units. The second session, Chemical Detection, provided applications of lidar to the detection of atmospheric pollutants. Papers in the third session, Wind and Turbulence Measurements, described the Multi-center Airborne Coherent Atmospheric Wind Sensor (MACAWS) experiments, Doppler techniques for ground-based wind profiling and mesopause radial wind and temperature measurements utilizing a frequency-agile lidar system. The papers in the last two sessions, Recent Advanced in Lidar Technology and Techniques and Advanced Operational Lidars, provided insights into novel approaches, materials, and techniques that would be of value to the lidar community. Papers have been processed separately for inclusion on the data base.

  20. Solar Market Pathways Website

    Broader source: Energy.gov [DOE]

    The Solar Market Pathways website distributes key insights from 15 SunShot Initiative projects that are advancing solar deployment across the United States. These projects take a variety of approaches to develop actionable strategic plans to expand solar electricity use for residential, community, and commercial properties.

  1. Solar Market Pathways

    Broader source: Energy.gov [DOE]

    The Solar Market Pathways website distributes key insights from 15 SunShot Initiative projects that are advancing solar deployment across the United States. These projects take a variety of approaches to develop actionable strategic plans to expand solar electricity use for residential, community, and commercial properties.

  2. PROJECT PROFILE: Salt Lake City Corporation (Solar Market Pathways) |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Salt Lake City Corporation (Solar Market Pathways) PROJECT PROFILE: Salt Lake City Corporation (Solar Market Pathways) Title: Wasatch Solar Project WASATCH solar logo.png Funding Opportunity: Solar Market Pathways SunShot Subprogram: Soft Costs Location: Salt Lake City, UT Amount Awarded: $600,000 Awardee Cost Share: $164,645 Salt Lake City and its partners are developing a comprehensive long-term solar deployment strategy, which includes an analysis of the value of

  3. Theoretical analysis of the sequential proton-coupled electron transfer mechanisms for H2 oxidation and production pathways catalyzed by nickel molecular electrocatalysts

    SciTech Connect (OSTI)

    Fernandez, Laura; Horvath, Samantha; Hammes-Schiffer, Sharon

    2012-02-02

    The design of electrocatalysts for the oxidation and production of H2 is important for the development of alternative energy sources. This paper focuses on the electrocatalysts, where denotes 1,5-diaza-3,7-diphosphacyclooctane ligands with substituent groups R and R' covalently bound to the phosphorus and nitrogen atoms, respectively. Theoretical methods are used to investigate the mechanism of the step in the catalytic cycle corresponding to e ? for H2 oxidation and the reverse reaction for H2 production. This step involves electron transfer (ET) between the Ni complex and the electrode as well as proton transfer (PT) between the Ni and the N. The sequential mechanisms, PTET and ETPT, are investigated for the following (R,R) substituents: (Me,Me), (Ph,Ph), and (Ph,Bz), where Me, Ph, and Bz denote methyl, phenyl, and benzyl substituents. Density functional theory is used to calculate reduction potentials, pKas, and PT pathways, and Marcus theory is used to describe the electrochemical electron transfer, including the effects of solute and solvent reorganization energies. For the (Ph,Ph) and (Ph,Bz) systems, the sequential PTET mechanism would require surmounting a large free energy barrier for the initial PT step, followed by thermodynamically favorable or thermoneutral ET. The sequential ETPT mechanism for these systems would require a relatively large initial applied overpotential, followed by a PT reaction with a relatively low free energy barrier. Consistent with experimental data, the calculated overpotential required for the initial reduction in the ETPT mechanism is lower for the (Ph,Bz) system than for the (Ph,Ph) system. The concerted mechanism, in which the electron and proton transfer simultaneously without a stable intermediate, may be thermodynamically favorable and is a direction of future research. This material is based upon work supported as part of the Center for Molecular Electrocatalysis, an Energy Frontier Research Center funded by the

  4. Physics Topics - Plasma Couette Experiment - Cary Forest Group - UW Plasma

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Physics Physics Topics UW Madison Plasma Couette Experiment Physics Topics PCX HomeResearch MissionPhysics TopicsDeviceDiagnosticsContacts LinksPCX People CPLA Home Directory Publications Links University of Wisconsin Physics Department Department of Energy National Science Foundation Accretion Accretion is a fundamental process in astrophysics by which virtually all astrophysical bodies are formed. Due to gravity, the interstellar gas and plasma collapses into rotating disks around the

  5. Physics Topics - Rotating Wall Machine - UW Plasma Physics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Physics Topics UW Madison Line Tied Reconnection Experiment Physics Topics LTRX HomeResearch MissionLTRX DevicePhysics TopicsDiagnosticsLTRX GalleryLTRX People CPLA Home Directory Publications Links University of Wisconsin Physics Department Department of Energy National Science Foundation Reconnection in a line-tied plasma Stability of zero-net-current equilibria Stability of hollow current equilibria Magnetic Launching of Astrophysical Jets

  6. Energy Department Announces New Grant Topics to Help Small Businesses

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Develop Clean Energy Technologies | Department of Energy Grant Topics to Help Small Businesses Develop Clean Energy Technologies Energy Department Announces New Grant Topics to Help Small Businesses Develop Clean Energy Technologies October 27, 2014 - 2:41pm Addthis The Energy Department's Office of Energy Efficiency and Renewable Energy (EERE) today announced nine topics and 26 new subtopics under its Small Business Innovation Research (SBIR) and Technology Transfer (STTR) programs that

  7. Manufacturing Innovation Multi-Topic Workshop Report | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Manufacturing Innovation Multi-Topic Workshop Report Manufacturing Innovation Multi-Topic Workshop Report The U.S. Department of Energy (DOE) and Department of Defense (DoD) held a Manufacturing Innovation Topics Workshop on October 8 and 9, 2014. Representatives from industry, academia, DOE national laboratories, and DoD centers gathered in Fort Worth TX to hear keynote addresses and participate in workshop breakout sessions. The Workshop Report is listed below. U.S DOE and DoD Manufacturing

  8. TEC Working Group Topic Groups Archives Communications Conference Call

    Office of Environmental Management (EM)

    Summaries | Department of Energy Communications Conference Call Summaries TEC Working Group Topic Groups Archives Communications Conference Call Summaries Conference Call Summaries Conference Call Summary April 2000 (91.86 KB) Conference Call Summary February 1999 (11.81 KB) Conference Call Summary November 1998 (54.77 KB) More Documents & Publications TEC Working Group Topic Groups Archives Communications Meeting Summaries TEC Working Group Topic Groups Tribal Conference Call Summaries

  9. TEC Working Group Topic Groups Archives Communications | Department of

    Office of Environmental Management (EM)

    Energy Communications TEC Working Group Topic Groups Archives Communications The Communications Topic Group was convened in April 1998 to improve internal and external strategic level communications regarding DOE shipments of radioactive and other hazardous materials. Major issues under consideration by this Topic Group include: - Examination of DOE external and internal communications processes; - Roles and responsibilities when communicating with a diverse range of stakeholders; and -

  10. TEC Working Group Topic Groups Archives Training - Medical Training |

    Office of Environmental Management (EM)

    Department of Energy Training - Medical Training TEC Working Group Topic Groups Archives Training - Medical Training The TEC Training and Medical Training Issues Topic Group was formed to address the training issues for emergency responders in the event of a radioactive material transportation incident. The Topic Group first met in 1996 to assist DOE in developing an approach to address radiological emergency response training needs and to avoid redundancy of existing training materials. The

  11. TEC Working Group Topic Groups Rail Archived Documents | Department of

    Office of Environmental Management (EM)

    Energy Archived Documents TEC Working Group Topic Groups Rail Archived Documents ARCHIVED DOCUMENTS Inspections Summary Matrix (49.36 KB) TEC Transportation Safety WIPP-PIG Rail Comparison (130.46 KB) Regulatory Summary Matrix (62.08 KB) More Documents & Publications TEC Working Group Topic Groups Rail Key Documents TEC Working Group Topic Groups Rail Meeting Summaries TEC Meeting Summaries - September 2005 Presentations

  12. TEC Working Group Topic Groups Security Key Documents | Department of

    Office of Environmental Management (EM)

    Energy Key Documents TEC Working Group Topic Groups Security Key Documents Key Documents Security TG Work Plan August 7, 2006 (24.31 KB) Security Lessons Learned Document August 2, 2006 (40.77 KB) Security Module (635.1 KB) STG Terms and Definitions from DOE 470.4 (18.54 KB) More Documents & Publications TEC Working Group Topic Groups Security Meeting Summaries TEC Meeting Summaries - April 2005 Presentations TEC Working Group Topic Groups Security Conference Call Summaries

  13. TEC Working Group Topic Groups Security Meeting Summaries | Department of

    Office of Environmental Management (EM)

    Energy Meeting Summaries TEC Working Group Topic Groups Security Meeting Summaries Meeting Summaries Green Bay STG Meeting Summary- September 14, 2006 (28.22 KB) Washington STG Meeting Summary - March 14, 2006 (25.61 KB) Pueblo STG Meeting Summary - September 22, 2005 (18.7 KB) More Documents & Publications TEC Working Group Topic Groups Security Conference Call Summaries TEC Meeting Summaries - September 2006 TEC Working Group Topic Groups Security Key Documents

  14. TRIBAL ISSUES TOPIC GROUP MEETING SUMMARY Milwaukee, WI July 1998

    Office of Environmental Management (EM)

    Milwaukee, WI July 1998 The Topic Group is developing a process to identify appropriate Topic Group membership, and will be working on a protocol for identifying and inviting individual tribes to participate he group identified five actions: (1) catalogue tribal transportation issues; (2) identify a level of tribal awareness of DOE transportation issues; (3) examine funding and tribal support; (4) develop a process for Tribal Topic Group membership; and (5) review the best channels to

  15. 2013 February POTENTIAL COMMITTEE MEETING TOPICS HAB Committee: RAP

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Page 1 of 3 2013 February POTENTIAL COMMITTEE MEETING TOPICS HAB Committee: RAP Committee meeting: Tuesday, February 12 from 9 a.m. - 4 p.m. Agenda Topic When is HAB input needed? Issue Managers (* = lead) Agency Lead(s) Time to Allocate (minutes) Title: Framing Discussion: Central Plateau Groundwater and Vadose Zone Modeling (JOINT TOPIC W/ TWC) 2013 Priority: Groundwater Modeling Purpose: To hear a report-out from issue managers on their work regarding Central Plateau groundwater and vadose

  16. Integrated Operation Scenarios ITPA Topical Group Meeting | Princeton

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Plasma Physics Lab 20, 2010, 9:00am to April 23, 2010, 5:00pm Conference Princeton, NJ Integrated Operation Scenarios ITPA Topical Group Meeting Integrated Operation Scenarios ITPA Topical Group Meeting Contact Information Website: Integrated Operation Scenarios ITPA Topical Group Meeting Coordinator(s): Kathleen Lukazik KLukazik@pppl.gov Host(s): Chuck Kessel ckessel@pppl.gov PPPL Entrance Procedures Visitor Information, Directions, Security at PPPL As a federal facility, the Princeton

  17. Collaboration Topics - Visualization | National Nuclear Security

    National Nuclear Security Administration (NNSA)

    Administration | (NNSA) Visualization This collaboration area focuses on visualization and data analysis and centers on the open source development of the Visualization Toolkit (VTK), which forms the basis of our customized visualization and analysis tools (ParaView, VisIt and LOVE). We are partnering on common VTK needs and working on methods for visualizing and analyzing data on advanced architectures that are memory and I/O constrained. Accomplishments 1) Portions of the CEA visualization

  18. SBIR/STTR FY16 Phase 1 Release 1 Topics Announced-Includes Hydrogen...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Production and Fuel Cell Membrane Topics SBIRSTTR FY16 Phase 1 Release 1 Topics Announced-Includes Hydrogen Production and Fuel Cell Membrane Topics August 18, 2015 - ...

  19. OSTIblog Articles in the Bayesian Inference Topic | OSTI, US...

    Office of Scientific and Technical Information (OSTI)

    he was also a mathematician and developed a strong interest in probability late in life. ... After his death, a good friend... Related Topics: Bayesian Inference, Oak Ridge National ...

  20. Topic B Awardee: Eastern Interconnection States' Planning Council...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Eastern Interconnection States' Planning Council Topic B Awardee: Eastern Interconnection States' Planning Council The Eastern Interconnection States' Planning Council (EISPC) is ...

  1. OSTIblog Articles in the nuclear science Topic | OSTI, US Dept...

    Office of Scientific and Technical Information (OSTI)

    science Topic National Nuclear Science Week - January 23-27, 2012 by Kate Bannan 24 Jan, 2012 in Science Communications Nuclear science comprises many fields. From astrophysics to ...

  2. OSTIblog Articles in the Nuclear Energy University Programs Topic...

    Office of Scientific and Technical Information (OSTI)

    Nuclear Energy University Programs Topic National Nuclear Science Week - January 23-27, 2012 by Kate Bannan 24 Jan, 2012 in Science Communications Nuclear science comprises many ...

  3. Funding Topics for Small Business Innovation Research and Small...

    Energy Savers [EERE]

    (FOAs), which invite established or new small businesses to apply for SBIRSTTR grants within specific topics that advance the missions of its individual technology offices. ...

  4. OSTIblog Articles in the space technology Topic | OSTI, US Dept...

    Office of Scientific and Technical Information (OSTI)

    space technology Topic James Van Allen - Space Pioneer by Kathy Chambers 10 Jun, 2016 in jamesvanallenwcaption.jpg James Van Allen's space instrumentation innovations and his... ...

  5. OSTIblog Articles in the DOE Science Showcase Topic | OSTI, US...

    Office of Scientific and Technical Information (OSTI)

    Science Showcase Topic OSTI's Amazing Dr. Watson by Kathy Chambers 17 Apr, 2013 in ... few very interesting white papers in OSTI's monthly Science Showcase on OSTI's Home Page. ...

  6. OSTIblog Articles in the Science Conference Proceedings Topic...

    Office of Scientific and Technical Information (OSTI)

    Science Conference Proceedings Topic OSTI Is Re-Focusing and Re-Balancing Its Operations - ... (NLE) - Beta, osti, OSTI Homepage, Science Accelerator, Science Conference ...

  7. OSTIblog Articles in the transformative science Topic | OSTI...

    Office of Scientific and Technical Information (OSTI)

    transformative science Topic Transparency in Government and Transformative Science by Dr. Jeffrey Salmon 04 May, 2009 in Personal Perspectives 1528 IMG0918.20.JPG Transparency in ...

  8. AMO Requests Technical Topics Suitable for a Manufacturing Innovation...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Innovation Institute AMO Requests Technical Topics Suitable for a Manufacturing Innovation Institute April 17, 2014 - 12:23pm Addthis The Advanced Manufacturing Office...

  9. OSTIblog Articles in the DOE's Solar Decathlon Topic | OSTI,...

    Office of Scientific and Technical Information (OSTI)

    DOE's Solar Decathlon Topic University of Tennessee Knoxville in DOE's .EDUconnections ... chart or developing "Living Light", a net-zero energy home for DOE's Solar Decathlon. ...

  10. OSTIblog Articles in the preservation Topic | OSTI, US Dept of...

    Office of Scientific and Technical Information (OSTI)

    resources are in jeopardy should a disaster strike. One way to... Related Topics: digitization, DOE Green Energy, preservation, Science.gov, ScienceCinema, ScienceEducation.gov

  11. Focus Group Meeting (Topical Wrap-Up) | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Wrap-Up) Focus Group Meeting (Topical Wrap-Up) Meeting Date: December 4, 2008 Meeting Agenda, Summary and Informational Materials Documents Available for Download Meeting Agenda (22 KB) Meeting Summary (83.05 KB) 2008 Topical Meeting Executive Summaries and Actions Lists (90.46 KB) Union Topical Priorities - 2008 (32.86 KB) Draft Topical Action Matrix - 2008 (81.56 KB) HSS Office of Worker Health and Safety Former Worker/EEOIPCA Activities and Initiatives (41.3 KB) HSS/Union Training Work

  12. Small Business Innovation Research Program Topics- October 28, 2013

    Office of Energy Efficiency and Renewable Energy (EERE)

    This document outlines the topics covered by the 2013-14 SBIR funding opportunity announcement and show the details of how to apply for the program.

  13. OSTIblog Articles in the Supercomputers Topic | OSTI, US Dept...

    Office of Scientific and Technical Information (OSTI)

    mathematically at an early age. His grandfather taught him how to do mathematical... Related Topics: effective field theory, renormalization, Supercomputers, theoretical physics

  14. OSTIblog Articles in the High-performance computing Topic | OSTI...

    Office of Scientific and Technical Information (OSTI)

    Research, ASCR, climate change, earth systems modeling, High-performance computing, ... ORNL's National Center for Computational Sciences... Related Topics: High-performance ...

  15. OSTIblog Articles in the energy efficiency Topic | OSTI, US Dept...

    Office of Scientific and Technical Information (OSTI)

    energy efficiency Topic Energypledge by Erin Anderson 06 Mar, 2013 in Science ... recently contributed to the Department of Energy's (DOE) "2013 Energy Pledge Campaign" ...

  16. TEC Working Group Topic Groups Rail Key Documents | Department...

    Office of Environmental Management (EM)

    Rail Key Documents TEC Working Group Topic Groups Rail Key Documents KEY DOCUMENTS Radiation Monitoring Subgroup Intermodal Subgroup Planning Subgroup Current FRA State Rail Safety ...

  17. TEC Working Group Topic Groups Rail Conference Call Summaries...

    Office of Environmental Management (EM)

    Summaries Inspections Subgroup TEC Working Group Topic Groups Rail Conference Call Summaries Inspections Subgroup Inspections Subgroup PDF icon April 6, 2006 PDF icon February 23,...

  18. TEC Working Group Topic Groups Archives Mechanics of Funding...

    Office of Environmental Management (EM)

    Mechanics of Funding and Techical Assistance TEC Working Group Topic Groups Archives Mechanics of Funding and Techical Assistance Mechanics of Funding and Techical Assistance Items...

  19. TEC Working Group Topic Groups Tribal Conference Call Summaries...

    Office of Environmental Management (EM)

    Conference Call Summaries TEC Working Group Topic Groups Tribal Conference Call Summaries Conference Call Summaries PDF icon March 12, 2008 PDF icon October 3, 2007 PDF icon...

  20. TEC Working Group Topic Groups Archives Communications Conference...

    Office of Environmental Management (EM)

    Communications Conference Call Summaries TEC Working Group Topic Groups Archives Communications Conference Call Summaries Conference Call Summaries PDF icon Conference Call Summary...

  1. TEC Working Group Topic Groups Archives Communications Meeting...

    Office of Environmental Management (EM)

    Archives Communications Meeting Summaries TEC Working Group Topic Groups Archives Communications Meeting Summaries Meeting Summaries PDF icon Milwaukee TEC Meeting, Communications...

  2. TEC Working Group Topic Groups Section 180(c) Key Documents ...

    Office of Environmental Management (EM)

    Key Documents TEC Working Group Topic Groups Section 180(c) Key Documents Key Documents Briefing Package for Section 180(c) Implementation - July 2005 PDF icon Executive Summary...

  3. OSTIblog Articles in the DOE laboratories Topic | OSTI, US Dept...

    Office of Scientific and Technical Information (OSTI)

    Simply enter a search, and ScienceCinema's innovative audio indexing and speech ... and submitted by DOE... Related Topics: audio indexing, DOE laboratories, open ...

  4. OSTIblog Articles in the nuclear weapons technology Topic | OSTI...

    Office of Scientific and Technical Information (OSTI)

    noted by Pete Domenici, senior fellow at the Bipartisan Policy... Related Topics: Bureau of Mines, communications, hydraulic fracturing, nasa, nuclear weapons technology, Oil Shale

  5. OSTIblog Articles in the hydraulic fracturing Topic | OSTI, US...

    Office of Scientific and Technical Information (OSTI)

    noted by Pete Domenici, senior fellow at the Bipartisan Policy... Related Topics: Bureau of Mines, communications, hydraulic fracturing, nasa, nuclear weapons technology, Oil Shale

  6. TEC Working Group Topic Groups Rail Key Documents Radiation Monitoring...

    Office of Environmental Management (EM)

    Radiation Monitoring Subgroup TEC Working Group Topic Groups Rail Key Documents Radiation Monitoring Subgroup Radiation Monitoring Subgroup PDF icon Draft Work Plan - February 4,...

  7. OSTIblog Articles in the theoretical physics Topic | OSTI, US...

    Office of Scientific and Technical Information (OSTI)

    theoretical physics Topic The Remarkable Legacy of Kenneth Geddes Wilson by Kathy Chambers ... Laureate Kenneth Geddes Wilson (1936 -2013) forever changed how we think about physics. ...

  8. OSTIblog Articles in the OSTI Homepage Topic | OSTI, US Dept...

    Office of Scientific and Technical Information (OSTI)

    STIP is a robust and effective collaboration across the DOE... Related Topics: .EDUconnections, Adopt-A-Doc, DOE Green Energy, DOE STI, journal literature, National Library of ...

  9. OSTIblog Articles in the Products and Content Topic | OSTI, US...

    Office of Scientific and Technical Information (OSTI)

    ... STIP is a robust and effective collaboration across the DOE... Related Topics: .EDUconnections, Adopt-A-Doc, DOE Green Energy, DOE STI, journal literature, National Library of ...

  10. OSTIblog Articles in the Science Accelerator Topic | OSTI, US...

    Office of Scientific and Technical Information (OSTI)

    STIP is a robust and effective collaboration across the DOE... Related Topics: .EDUconnections, Adopt-A-Doc, DOE Green Energy, DOE STI, journal literature, National Library of ...

  11. OSTIblog Articles in the quantum computing Topic | OSTI, US Dept...

    Office of Scientific and Technical Information (OSTI)

    in OSTI's monthly Science Showcase on OSTI's Home Page. This quiet, unassuming man crafts prolific papers on popular science topics of interest to the Department of Energy (DOE). ...

  12. OSTIblog Articles in the metamaterials Topic | OSTI, US Dept...

    Office of Scientific and Technical Information (OSTI)

    in OSTI's monthly Science Showcase on OSTI's Home Page. This quiet, unassuming man crafts prolific papers on popular science topics of interest to the Department of Energy (DOE). ...

  13. OSTIblog Articles in the DOE Virtual University Topic | OSTI...

    Office of Scientific and Technical Information (OSTI)

    integrates and makes searchable the disparate and decentralized... Related Topics: DOE Virtual University, mission, National Library of Energy (NLE) - Beta, strategy, training

  14. Topic A and B Awardee: Electric Reliability Council of Texas...

    Office of Environmental Management (EM)

    and B Awardee: Electric Reliability Council of Texas Topic A and B Awardee: Electric Reliability Council of Texas The Electric Reliability Council of Texas (ERCOT) manages the flow ...

  15. OSTIblog Articles in the alkaline membrane cells Topic | OSTI...

    Office of Scientific and Technical Information (OSTI)

    alkaline membrane cells Topic Fine tuning fuel cells by Kathy Chambers 14 Jun, 2012 in Products and Content 4314 ballardfuelcellcaption.jpg Fine tuning fuel cells Read more ...

  16. OSTIblog Articles in the electromagnetic Topic | OSTI, US Dept...

    Office of Scientific and Technical Information (OSTI)

    Related Topics: 70th Anniversary, atomic bomb, DOE Research & Development (R&D) Accomplishments, electromagnetic, gaseous diffusion, Manhattan Project, nuclear chain reaction, ...

  17. OSTIblog Articles in the Human Genome Project Topic | OSTI, US...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Related Topics: Charles DeLisi, DNA, DOE Research & Development (R&D) Accomplishments, genomics, Human Genome Project, Santa Fe Workshop, sequencing Read more... DOE Research ...

  18. OSTIblog Articles in the dissertations Topic | OSTI, US Dept...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Related Topics: dissertations, DOE Research & Development (R&D) Accomplishments, DOE Research and Development (R&D) Project Summaries, E-Print Network (EPN), Energy Citations ...

  19. OSTIblog Articles in the gaseous diffusion Topic | OSTI, US Dept...

    Office of Scientific and Technical Information (OSTI)

    Related Topics: 70th Anniversary, atomic bomb, DOE Research & Development (R&D) Accomplishments, electromagnetic, gaseous diffusion, Manhattan Project, nuclear chain reaction, ...

  20. OSTIblog Articles in the sequencing Topic | OSTI, US Dept of...

    Office of Scientific and Technical Information (OSTI)

    to the Human Genome initiative. Related Topics: Charles DeLisi, DNA, DOE Research & Development (R&D) Accomplishments, genomics, Human Genome Project, Santa Fe Workshop, sequencing

  1. OSTIblog Articles in the research-and-development Topic | OSTI...

    Office of Scientific and Technical Information (OSTI)

    research-and-development Topic Be on the Alert by Mary Schorn 15 Oct, 2009 in Products ... to key DOEOSTI resources that contain research and development results, project ...

  2. OSTIblog Articles in the reference linking Topic | OSTI, US Dept...

    Office of Scientific and Technical Information (OSTI)

    reference linking Topic OSTI and Reference Linking by Daphne Evans 13 May, 2008 in Technology OSTI actively supports the practice of Reference Linking. Also referred to as citation ...

  3. Events & Topics in Renewable Energy & the Environment | Photosynthetic...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Technologies campus, followed by a brief presentation. Topics will include home automation, the internet of things, wireless sensor networks and other smart technologies. The...

  4. Breakout Items Action Items Fixed Price Contracting Topic Group...

    Office of Environmental Management (EM)

    ... marketing products to medical emergency response community General Planning Three primary topics of ... DOE is likely to have substantial coordination problems of this type. ...

  5. OSTIblog Articles in the Information Bridge MARC Records Topic...

    Office of Scientific and Technical Information (OSTI)

    Related Topics: Information Bridge MARC Records, patents, Science Accelerator, SciTech Connect Full-Text MARC Records Read more... OSTI's Web Metrics - Partially Measuring Success ...

  6. HEC-DPSSL 2012 Workshop, Topics: National Ignition Facility ...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Potential Session Topics High Power Diode Arrays Laser Gain Media Laser Damage Resistance Thermal ModelingResults GainParasitics ModelingResults Laser Propagation Modeling ...

  7. OSTIblog Articles in the carbon dioxide Topic | OSTI, US Dept...

    Office of Scientific and Technical Information (OSTI)

    regions and seasons, increasing intensity and frequency of storm events, flooding and... Related Topics: carbon dioxide, carbon sequestration, climate change, greenhouse gases

  8. OSTIblog Articles in the coauthorship Topic | OSTI, US Dept of...

    Office of Scientific and Technical Information (OSTI)

    a certain critical temperature, and the sharp difference between the densities of water and water vapor disappears above a critical pressure. ... Related Topics: bettencourt, ...

  9. OSTIblog Articles in the bettencourt Topic | OSTI, US Dept of...

    Office of Scientific and Technical Information (OSTI)

    a certain critical temperature, and the sharp difference between the densities of water and water vapor disappears above a critical pressure. ... Related Topics: bettencourt, ...

  10. OSTIblog Articles in the scitech connect Topic | OSTI, US Dept...

    Office of Scientific and Technical Information (OSTI)

    ... STIP is a robust and effective collaboration across the DOE... Related Topics: .EDUconnections, Adopt-A-Doc, DOE Green Energy, DOE STI, journal literature, National Library of ...

  11. OSTIblog Articles in the journal literature Topic | OSTI, US...

    Office of Scientific and Technical Information (OSTI)

    STIP is a robust and effective collaboration across the DOE... Related Topics: .EDUconnections, Adopt-A-Doc, DOE Green Energy, DOE STI, journal literature, National Library of ...

  12. OSTIblog Articles in the Science Conference Proceedings Topic...

    Office of Scientific and Technical Information (OSTI)

    STIP is a robust and effective collaboration across the DOE... Related Topics: .EDUconnections, Adopt-A-Doc, DOE Green Energy, DOE STI, journal literature, National Library of ...

  13. OSTIblog Articles in the preservation Topic | OSTI, US Dept of...

    Office of Scientific and Technical Information (OSTI)

    tools and services. OSTI's most recent contributions to... Related Topics: digitization, DOE Green Energy, preservation, Science.gov, ScienceCinema, ScienceEducation.gov

  14. OSTIblog Articles in the deep web technologies Topic | OSTI,...

    Office of Scientific and Technical Information (OSTI)

    During that time, working in close partnership with Deep Web Technologies, we have made ... individual source in Science.gov.... Related Topics: deep web technologies, energy portal

  15. OSTIblog Articles in the energy portal Topic | OSTI, US Dept...

    Office of Scientific and Technical Information (OSTI)

    During that time, working in close partnership with Deep Web Technologies, we have made ... individual source in Science.gov.... Related Topics: deep web technologies, energy portal

  16. OSTIblog Articles in the scientific knowledge Topic | OSTI, US...

    Office of Scientific and Technical Information (OSTI)

    knowledge Topic The Benefits of Investments in Basic Research by Peter Lincoln 01 Nov, 2009 in Science Communications Long-term investments in basic research produce the major ...

  17. Pathway modeling of microarray data: A case study of pathway activity changes in the testis following in utero exposure to dibutyl phthalate (DBP)

    SciTech Connect (OSTI)

    Ovacik, Meric A.; Sen, Banalata; Euling, Susan Y.; Gaido, Kevin W.; Ierapetritou, Marianthi G.; Androulakis, Ioannis P.

    2013-09-15

    Pathway activity level analysis, the approach pursued in this study, focuses on all genes that are known to be members of metabolic and signaling pathways as defined by the KEGG database. The pathway activity level analysis entails singular value decomposition (SVD) of the expression data of the genes constituting a given pathway. We explore an extension of the pathway activity methodology for application to time-course microarray data. We show that pathway analysis enhances our ability to detect biologically relevant changes in pathway activity using synthetic data. As a case study, we apply the pathway activity level formulation coupled with significance analysis to microarray data from two different rat testes exposed in utero to Dibutyl Phthalate (DBP). In utero DBP exposure in the rat results in developmental toxicity of a number of male reproductive organs, including the testes. One well-characterized mode of action for DBP and the male reproductive developmental effects is the repression of expression of genes involved in cholesterol transport, steroid biosynthesis and testosterone synthesis that lead to a decreased fetal testicular testosterone. Previous analyses of DBP testes microarray data focused on either individual gene expression changes or changes in the expression of specific genes that are hypothesized, or known, to be important in testicular development and testosterone synthesis. However, a pathway analysis may inform whether there are additional affected pathways that could inform additional modes of action linked to DBP developmental toxicity. We show that Pathway activity analysis may be considered for a more comprehensive analysis of microarray data.

  18. Pathways for Algal Biofuels

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    DEPARTMENT OF ENERGY BIOMASS PROGRAM Pathways for Algal Biofuels November 27, 2012 Daniel B. Fishman Lead Technology Development Manager 2 | Biomass Program eere.energy.gov Adds value to unproductive or marginal lands of a range of biofuel feedstocks suitable for diesel and aviation fuels Activities include R&D on algal feedstocks and issues related to the sustainable production of algae-derived biofuels. Algae Feedstocks Courtesy Sapphire Courtesy Sapphire Courtesy University of Arizona 3

  19. DEVELOPMENT OF A NOVEL GAS PRESSURIZED STRIPPING (GPS)-BASED TECHNOLOGY FOR CO2 CAPTURE FROM POST-COMBUSTION FLUE GASES Topical Report: Techno-Economic Analysis of GPS-based Technology for CO2 Capture

    SciTech Connect (OSTI)

    Chen, Shiaoguo

    2015-09-30

    This topical report presents the techno-economic analysis, conducted by Carbon Capture Scientific, LLC (CCS) and Nexant, for a nominal 550 MWe supercritical pulverized coal (PC) power plant utilizing CCS patented Gas Pressurized Stripping (GPS) technology for post-combustion carbon capture (PCC). Illinois No. 6 coal is used as fuel. Because of the difference in performance between the GPS-based PCC and the MEA-based CO2 absorption technology, the net power output of this plant is not exactly 550 MWe. DOE/NETL Case 11 supercritical PC plant without CO2 capture and Case 12 supercritical PC plant with benchmark MEA-based CO2 capture are chosen as references. In order to include CO2 compression process for the baseline case, CCS independently evaluated the generic 30 wt% MEA-based PCC process together with the CO2 compression section. The net power produced in the supercritical PC plant with GPS-based PCC is 647 MW, greater than the MEA-based design. The levelized cost of electricity (LCOE) over a 20-year period is adopted to assess techno-economic performance. The LCOE for the supercritical PC plant with GPS-based PCC, not considering CO2 transport, storage and monitoring (TS&M), is 97.4 mills/kWh, or 152% of the Case 11 supercritical PC plant without CO2 capture, equivalent to $39.6/tonne for the cost of CO2 capture. GPS-based PCC is also significantly superior to the generic MEA-based PCC with CO2 compression section, whose LCOE is as high as 109.6 mills/kWh.

  20. Career Pathways | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Career Pathways Career Pathways The Energy/National Nuclear Security Administration (NNSA) Career Pathways Program is an innovative employment program targeting students and recent college graduates. If you are seeking an entry-level federal job or a federal internship, then check out our various opportunities! Intern Program The Pathways intern program allows students taking at least a half-time course load in an accredited high school, home schooling program, technical school, vocational

  1. OSTIblog Articles in the proceedings Topic | OSTI, US Dept of Energy Office

    Office of Scientific and Technical Information (OSTI)

    of Scientific and Technical Information proceedings Topic

  2. OSTIblog Articles in the visualizations Topic | OSTI, US Dept of Energy

    Office of Scientific and Technical Information (OSTI)

    Office of Scientific and Technical Information visualizations Topic

  3. Collaboration Topics - Meshing | National Nuclear Security Administration |

    National Nuclear Security Administration (NNSA)

    (NNSA) Meshing This work focuses on automatic algorithms for 3-D mesh generation and their extension to scalable parallel environments. The objective is to explore new theoretical advancements and develop new algorithms in mesh generation that will lead to practical advances in automatic meshing with an emphasis on all-hexahedral mesh generation technology. The development of technologies to facilitate model preparation for analysis such as CAD support for meshing and geometry simplification

  4. Collaboration Topics - System Software | National Nuclear Security

    National Nuclear Security Administration (NNSA)

    Administration | (NNSA) System Software This collaboration focuses on research and development of parallel file system interfaces and tools, system resource management capabilities, operating system evaluation, and software for high-performance interconnects. Current activities include the test and evaluation of technologies and tools associated with the Lustre parallel file system, the development and analysis of middleware to encapsulate application I/O requirements and abstract the

  5. Mini Grid Renewable Energy-Economic and Financial Analysis |...

    Open Energy Info (EERE)

    Energy Topics: Finance, Implementation, Market analysis, Background analysis Website: web.worldbank.orgWBSITEEXTERNALTOPICSEXTENERGY2EXTRENENERGYTK0,, Country: Sri Lanka,...

  6. Improving carbon fixation pathways

    SciTech Connect (OSTI)

    Ducat, DC; Silver, PA

    2012-08-01

    A recent resurgence in basic and applied research on photosynthesis has been driven in part by recognition that fulfilling future food and energy requirements will necessitate improvements in crop carbon-fixation efficiencies. Photosynthesis in traditional terrestrial crops is being reexamined in light of molecular strategies employed by photosynthetic microbes to enhance the activity of the Calvin cycle. Synthetic biology is well-situated to provide original approaches for compartmentalizing and enhancing photosynthetic reactions in a species independent manner. Furthermore, the elucidation of alternative carbon-fixation routes distinct from the Calvin cycle raises possibilities that novel pathways and organisms can be utilized to fix atmospheric carbon dioxide into useful materials.

  7. Solar Market Pathways | Department of Energy

    Energy Savers [EERE]

    Solar Market Pathways Solar Market Pathways The Solar Market Pathways program supports 15 SunShot projects that are advancing solar deployment across the United States. These...

  8. Hydrogen Pathway Cost Distributions | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Pathway Cost Distributions Hydrogen Pathway Cost Distributions Presentation on hydrogen pathway cost distributions presented January 25, 2006. PDF icon wkshpstorageuihlein.pdf...

  9. Analysis of the Durability of PEM FC Membrane Electrode Assemblies in Automotive Applications through the Fundamental Understanding of Membrane and MEA Degradation Pathways

    SciTech Connect (OSTI)

    Perry, Randal L.

    2013-10-31

    The Project focused on mitigation of degradation processes on membrane electrode assemblies. The approach was to develop a model to improve understanding of the mechanisms, and to use it to focus mitigation strategies. The detailed effects of various accelerated stress tests (ASTs) were evaluated to determine the best subset to use in model development. A combination of ASTs developed by the Fuel Cell Commercialization Conference of Japan and the Fuel Cell Tech Team were selected for use. The ASTs were compared by measuring effects on performance, running in-situ diagnostics, and performing microscopic analyses of the membrane electrode assemblies after the stress tests were complete. Nissan ran FCCJ AST protocols and performed in situ and ex-situ electrochemical testing. DuPont ran FCTT and USFCC AST protocols, performed scanning and transmission electron microscopy and ran in-situ electrochemical tests. Other ex-situ testing was performed by IIT, along with much of the data analysis and model development. These tests were then modified to generate time-dependent data of the degradation mechanisms. Three different catalyst types and four membrane variants were then used to generate data for a theoretically-based degradation model. An important part of the approach was to use commercially available materials in the electrodes and membranes made in scalable semiworks processes rather than lab-based materials. This constraint ensured all materials would be practicable for full-scale testing. The initial model for the electrode layer was tested for internal consistency and agreement with the data. A Java-based computer application was developed to analyze the time-dependent AST data using polarization curves with four different cathode gas feeds and generate model parameters. Data showed very good reproducibility and good consistency as cathode catalyst loadings were varied. At the point of termination of the project, a basic electrode model was in hand with several

  10. Some topics in the spatial bispectra

    SciTech Connect (OSTI)

    Sullivan, E.

    1994-11-15

    The bispectrum can be defined as the triple fourier transform of the third order cumulant of a data series. Up to the present, except in image analysis, most work on the bispectrum has treated time series. Recently, however, there has been interest in using the bispectrum in acoustic array processing. After a look at some issues involving sampling frequencies and symmetries of the bispectrum in general, two applications of the spatial bispectrum to underwater acoustic array processing will be discussed. One is a method of processing against loss of spatial coherence in towed arrays, which takes the form of a one-dimensional image, and the other is a look at the role of spatial bispectra in matched-field processing, which is a form of model-based processing used for the localization of acoustic sound sources.