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  1. Origin State>> CA ID ID ID IL KY MD NM NM NY NY OH SC TN TN

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    MD NM NM NY NY OH SC TN TN TN, WA, CA TN TN TN TN TX Total Shipments by Route Lawrence Livermore National Laboratory Advanced Mixed Waste Treatment Project Batelle Energy Alliance Idaho National Laboratory Argonne National Laboratory Paducah Gaseous Diffusion Plant Aberdeen Proving Ground Los Alamos National Laboratory Sandia National Laboratory Brookhaven National Laboratory West Valley Environmental Services Portsmouth Gaseous Diffusion Plant Savannah River Site Duratek/Energy Solutions Babcox

  2. Origin State>> CA ID ID ID IL MD NM NM NV NY NY OH SC TN TN

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NV NY NY OH SC TN TN TN, WA, CA TN TN TN Total Shipments by Route Lawrence Livermore National Laboratory Batelle Energy Alliance Idaho National Laboratory Advanced Mixed Waste Treatment Project Argonne National Laboratory Aberdeen Proving Ground Sandia National Laboratory Los Alamos National Laboratory National Security Technologies Brookhaven National Laboratory West Valley Environmental Services Portsmouth Gaseous Diffusion Plant Savannah River Site Duratek/Energy Solutions Babcox & Wilcox

  3. Origin State>> CA CA ID ID IL KY NJ NM NY NY NV OH OH SC TN

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    SC TN TN TN TN TN TN TN TX Total Shipments by Route Lawrence Livermore National Laboratory Boeing/Rocketdyne Idaho National Labaratoy Advanced Mixed Waste Treatment Project Argonne National Laboratory Paducah Gaseous Diffusion Plant Princeton Plasma Physics Laboratory Sandia National Laboratory Brookhaven National Laboratory West Valley Demonstration Project National Security Technologies, Inc. Portsmouth Gaseous Diffusion Plant Fernald Closure Project Savannah River Site BWXT Y-12 Plant Duratek

  4. Origin State>> CA ID ID ID IL NM NM OH TN TN TN, WA, CA TN TN

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NM NM OH TN TN TN, WA, CA TN TN TN TN TX Total Shipments by Route Lawrence Livermore National Laboratory Batelle Energy Alliance Idaho National Laboratory Advanced Mixed Waste Treatment Project Argonne National Laboratory Sandia National Laboratory Los Alamos National Laboratory Portsmouth Gaseous Diffusion Plant Duratek/Energy Solutions Babcox & Wilcox Technical Services Y-12 Plant Materials & Energy Corporation (M&EC) Perma-Fix Nuclear Fuels Services Wastren Advantage, Inc.

  5. Origin State>> CA CA ID ID ID IL KY MD MO NM NM NY NY OH SC

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    MO NM NM NY NY OH SC TN TN TN, WA, CA TN TN TN TN Total Shipments by Route Lawrence Livermore National Laboratory General Atomics Batelle Energy Alliance Idaho National Laboratory Advanced Mixed Waste Treatment Project Argonne National Laboratory Paducah Gaseous Diffusion Plant Aberdeen Proving Grounds National Security Technologies Sandia National Laboratory Los Alamos National Laboratory Brookhaven National Laboratory CH2M Hill B&W West Valley, LLC Portsmouth Gaseous Diffusion Plant

  6. Origin State>> CA ID ID ID IL KY NV NY NY OH TN TN TN, WA, CA

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NV NY NY OH TN TN TN, WA, CA TN TN TN TN TX Total Shipments by Route Lawrence Livermore National Laboratory Advanced Mixed Waste Treatment Project Batelle Energy Alliance Idaho National Laboratory Argonne National Laboratory Paducah Gaseous Diffusion Plant National Security Technologies Brookhaven National Laboratory West Valley Environmental Services Portsmouth Gaseous Diffusion Plant Duratek/Energy Solutions Babcox & Wilcox Technical Services Y-12 Plant Materials & Energy Corporation

  7. Origin State>> CA ID ID IL IL KY NM NM NV NY OH TN TN TN, WA,

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    IL IL KY NM NM NV NY OH TN TN TN, WA, CA TN TN TN TN Total Shipments by Route Lawrence Livermore National Laboratory Batelle Energy Alliance Idaho National Laboratory Energx Argonne National Laboratory Argonne National Laboratory Paducah Gaseous Diffusion Plant Sandia National Laboratory Los Alamos National Laboratory National Security Technologies West Valley Environmental Services Portsmouth Gaseous Diffusion Plant Duratek/Energy Solutions Babcox & Wilcox Technical Services Y-12 Plant

  8. US ESC TN Site Consumption

    U.S. Energy Information Administration (EIA) Indexed Site

    ESC TN Site Consumption million Btu $0 $500 $1,000 $1,500 $2,000 $2,500 US ESC TN Expenditures dollars ALL ENERGY average per household (excl. transportation) 0 4,000 8,000 12,000 16,000 US ESC TN Site Consumption kilowatthours $0 $400 $800 $1,200 $1,600 US ESC TN Expenditures dollars ELECTRICITY ONLY average per household * Tennessee households consume an average of 79 million Btu per year, about 12% less than the U.S. average. * Average electricity consumption for Tennessee households is 33%

  9. Origin State>> CA ID ID ID IL MD NM NM NY OH TN TN TN, WA, CA

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NY OH TN TN TN, WA, CA TN TN TN TX Total Shipments by Route Lawrence Livermore National Laboratory Batelle Energy Alliance Idaho National Laboratory Advanced Mixed Waste Treatment Project Argonne National Laboratory Aberdeen Proving Ground Sandia National Laboratory Los Alamos National Laboratory Brookhaven National Laboratory Portsmouth Gaseous Diffusion Plant Duratek/Energy Solutions Babcox & Wilcox Technical Services Y-12 Plant Materials & Energy Corporation (M&EC) Perma-Fix

  10. DOE - Office of Legacy Management -- Oak Ridge TN Warehouse Site - TN 09

    Office of Legacy Management (LM)

    Oak Ridge TN Warehouse Site - TN 09 FUSRAP Considered Sites Oak Ridge, TN, Warehouses Alternate Name(s): Elza Gate Elza Gate Warehouse Area Melton Lake Industrial Park MED Warehouses TN.09-1 TN.09-8 Location: Meco Lane (formerly Antwerp Lane), Melton Industrial Park, Oak Ridge, Tennessee TN.09-7 Historical Operations: Stored pitchblende (high-grade uranium ore) and slag and tailings, which released uranium, radium, and thorium. TN.09-3 TN.09-7 TN.09-8 Eligibility Determination: Eligible TN.09-1

  11. Research Report SC-RR-710673

    Office of Scientific and Technical Information (OSTI)

    m 5 1fi?2 -*Trr r(V Ttr- Research Report SC-RR-710673 Way 1972 APPLICATION OF ... LABORATORIES O P F ' ' - ' ' ' ' c n cfR - t u t I i M J T c n ' T A i c c rtTrMi( ...

  12. DOE - Office of Legacy Management -- Knoxville Iron Co - TN 07

    Office of Legacy Management (LM)

    Knoxville Iron Co - TN 07 FUSRAP Considered Sites Site: KNOXVILLE IRON CO. (TN.07 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Knoxville , Tennessee TN.07-1 Evaluation Year: 1994 TN.07-2 TN.07-3 Site Operations: Melted uranium contaminated scrap metal in order to test industrial hygiene procedures in the mid-1950s. TN.07-1 Site Disposition: Eliminated - AEC license TN.07-2 Radioactive Materials Handled: Yes Primary Radioactive

  13. NERSC at SC13

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    3 NERSC at SC13 November 12, 2013 by Francesca Verdier SC13 takes place November 17-22 at Denver's Colorado Convention Center. NERSC is well represented at SC13, including: DOE National Labs booth #1327 Tutorials on Globus Online, OpenCL, Parallel I/O BOFs on HPC and the Web, erformance modeling, the Green500 list Papers on parallel I/O, compute-local non volatile memory Panel discussion on RDMA See Berkeley Lab at SC13. Subscribe via RSS Subscribe Browse by Date August 2016 June 2016 May 2016

  14. SC Johnson Waxdale Plant

    SciTech Connect (OSTI)

    2010-01-01

    This is a combined heat and power (CHP) project profile on a 6.4 MW CHP application at SC Johnson Waxdale Plant in Racine, Wisconsin.

  15. Auger analysis of scandium, Sc-Oxide, Sc-Deuteride and Sc-Nitride

    SciTech Connect (OSTI)

    Moore, G.; Nelson, G.C.; Madden, H.H.

    1996-09-01

    Elemental scandium, Sc-oxide, Sc-hydride and Sc-nitride films were investigated using Auger electron spectroscopy in a study of the interaction of scandium with hydrogen and atmospheric gases. A catalog of Sc Auger spectra representative of Sc-metal, Sc-0, Sc-H and Sc-N bonding is presented. Changes in spectral features unique to the changes in scandium matrix are identified. Comparisons with theoretical calculations, along with variation in the experimental conditions for recording the Auger data, enabled the Sc spectra found in separate low and high energy regions to be identified with M-shell and L-shell core excitations, respectively.

  16. SC Projects | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    OPA Home About Project Management SC Projects Review Dates (updated July 2016) Project Construction Photos Other Links SC Federal Project Directors (FPD) and FPD Resources Contact ...

  17. SC e-journals

    Office of Scientific and Technical Information (OSTI)

    SC e-journals Home Browse ABOUTFAQ HELP Desktop access to journals of interest to the Office of Science Search Options Web of Science Search citations for a wide range of ...

  18. NERSC at SC11

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and experience with thousands of attendees at the annual conference sponsored by the IEEE Computer Society and ACM SIGARCH. SC11 will be held Nov. 12-16 in Seattle. Subscribe...

  19. AT-TN: Mr. R. L. Rudolph

    Office of Legacy Management (LM)

    MAR 1 ? 7982 3echW tiational, Inc. AT-TN: Mr. R. L. Rudolph PO Box 350 Oak Ridge, TFi 37830 Gentlemen: CRITERIA FOR REMEDIAL ACTION AT ACID/PUEBLO AND BAY0 CANYONS; REQUEST FOR COST/BENEFIT ANALYSES OF REMEDIAL ACTION OPTIONS AT THE CANYONS Enclosed are several pieces of cqrespondence related to AcldjPueblo * and Bayo Canyons. . . . . . . . . . . . . . First, EP has concurred with the remedial action DATE criteria for the New Mexico sftes that were proposed to them on August 20, 1987 (wfth the

  20. SC Correspondence Control Center (SC CCC) | U.S. DOE Office of...

    Office of Science (SC) Website

    SC Correspondence Control Center (SC CCC) Human Resources and Administration (HRA) HRA Home About Human Resources Administration SC Correspondence Control Center (SC CCC) Contact...

  1. TN Energy Efficient Schools Initiative GSHP Program | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    TN Energy Efficient Schools Initiative GSHP Program TN Energy Efficient Schools Initiative GSHP Program Project objectives: Develop methods to make GSHPs more affordable for Tennessee school districts, by innovative design techniques, reducing the up-front cost of the technology, and by providing an innovative method of financing construction. Three school districts have been chosen as test beds for the innovations. gshp_townsend_tn_schools.pdf (170.01 KB) More Documents & Publications

  2. Services | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Integrated Support Center (ISC) ISC Home About Services Freedom of Information Act (FOIA) Privacy Act NEPA Documents Contact Information Integrated Support Center Roxanne Purucker U.S. Department of Energy 9800 S. Cass Avenue Argonne, IL 60439 P: (630) 252-2110 Kenneth Tarcza U.S. Department of Energy 200 Administration Road Oak Ridge, TN 37830 P: (865) 576-4444 Services Print Text Size: A A A FeedbackShare Page Service Plan of the SC Integrated Support Center .pdf file (3.0MB) Human Resources

  3. National Lab., TN (United States)] 54 ENVIRONMENTAL SCIENCES...

    Office of Scientific and Technical Information (OSTI)

    G.M. Oak Ridge National Lab., TN (United States) 54 ENVIRONMENTAL SCIENCES; GROUND WATER; REMEDIAL ACTION; TECHNETIUM 99; SORPTION; PERTECHNETATES Groundwater used for...

  4. DOE - Office of Legacy Management -- Vitro Corp of America - TN 04

    Office of Legacy Management (LM)

    TN 04 FUSRAP Considered Sites Site: Vitro Corp. of America (TN.04) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: Heavy Minerals Company Vitro Chemical Company TN.04-4 TN.04-5 Location: 4000 North Hawthorne Street , Chattanooga , Tennessee TN.04-5 Evaluation Year: 1990 TN.04-1 Site Operations: Processed mineral monazite to produce a thorium-uranium hydroxide and a series of rare earth products. TN.04-4 Site Disposition: Eliminated - Site

  5. SC Johnson Waxdale Plant | Open Energy Information

    Open Energy Info (EERE)

    SC Johnson Waxdale Plant Jump to: navigation, search Name SC Johnson Waxdale Plant Facility SC Johnson Waxdale Plant Sector Wind energy Facility Type Community Wind Facility Status...

  6. Measurement of the direct <mi>CP> -violating parameter <mi>Ami><mi>CP> in the decay <mi>D>+<mi>Kmi>-<mimi>+<mi>π>+

    SciTech Connect (OSTI)

    Abazov, V. M.; Abbott, B.; Acharya, B. S.; Adams, M.; Adams, T.; Agnew, J. P.; Alexeev, G. D.; Alkhazov, G.; Alton, A.; Askew, A.; Atkins, S.; Augsten, K.; Avila, C.; Badaud, F.; Bagby, L.; Baldin, B.; Bandurin, D. V.; Banerjee, S.; Barberis, E.; Baringer, P.; Bartlett, J. F.; Bassler, U.; Bazterra, V.; Bean, A.; Begalli, M.; Bellantoni, L.; Beri, S. B.; Bernardi, G.; Bernhard, R.; Bertram, I.; Besançon, M.; Beuselinck, R.; Bhat, P. C.; Bhatia, S.; Bhatnagar, V.; Blazey, G.; Blessing, S.; Bloom, K.; Boehnlein, A.; Boline, D.; Boos, E. E.; Borissov, G.; Borysova, M.; Brandt, A.; Brandt, O.; Brock, R.; Bross, A.; Brown, D.; Bu, X. B.; Buehler, M.; Buescher, V.; Bunichev, V.; Burdin, S.; Buszello, C. P.; Camacho-Pérez, E.; Casey, B. C. K.; Castilla-Valdez, H.; Caughron, S.; Chakrabarti, S.; Chan, K. M.; Chandra, A.; Chapon, E.; Chen, G.; Cho, S. W.; Choi, S.; Choudhary, B.; Cihangir, S.; Claes, D.; Clutter, J.; Cooke, M.; Cooper, W. E.; Corcoran, M.; Couderc, F.; Cousinou, M. -C.; Cutts, D.; Das, A.; Davies, G.; de Jong, S. J.; De La Cruz-Burelo, E.; Déliot, F.; Demina, R.; Denisov, D.; Denisov, S. P.; Desai, S.; Deterre, C.; DeVaughan, K.; Diehl, H. T.; Diesburg, M.; Ding, P. F.; Dominguez, A.; Dubey, A.; Dudko, L. V.; Duperrin, A.; Dutt, S.; Eads, M.; Edmunds, D.; Ellison, J.; Elvira, V. D.; Enari, Y.; Evans, H.; Evdokimov, V. N.; Fauré, A.; Feng, L.; Ferbel, T.; Fiedler, F.; Filthaut, F.; Fisher, W.; Fisk, H. E.; Fortner, M.; Fox, H.; Fuess, S.; Garbincius, P. H.; Garcia-Bellido, A.; García-González, J. A.; Gavrilov, V.; Geng, W.; Gerber, C. E.; Gershtein, Y.; Ginther, G.; Gogota, O.; Golovanov, G.; Grannis, P. D.; Greder, S.; Greenlee, H.; Grenier, G.; Gris, Ph.; Grivaz, J. -F.; Grohsjean, A.; Grünendahl, S.; Grünewald, M. W.; Guillemin, T.; Gutierrez, G.; Gutierrez, P.; Haley, J.; Han, L.; Harder, K.; Harel, A.; Hauptman, J. M.; Hays, J.; Head, T.; Hebbeker, T.; Hedin, D.; Hegab, H.; Heinson, A. P.; Heintz, U.; Hensel, C.; Heredia-De La Cruz, I.; Herner, K.; Hesketh, G.; Hildreth, M. D.; Hirosky, R.; Hoang, T.; Hobbs, J. D.; Hoeneisen, B.; Hogan, J.; Hohlfeld, M.; Holzbauer, J. L.; Howley, I.; Hubacek, Z.; Hynek, V.; Iashvili, I.; Ilchenko, Y.; Illingworth, R.; Ito, A. S.; Jabeen, S.; Jaffré, M.; Jayasinghe, A.; Jeong, M. S.; Jesik, R.; Jiang, P.; Johns, K.; Johnson, E.; Johnson, M.; Jonckheere, A.; Jonsson, P.; Joshi, J.; Jung, A. W.; Juste, A.; Kajfasz, E.; Karmanov, D.; Katsanos, I.; Kaur, M.; Kehoe, R.; Kermiche, S.; Khalatyan, N.; Khanov, A.; Kharchilava, A.; Kharzheev, Y. N.; Kiselevich, I.; Kohli, J. M.; Kozelov, A. V.; Kraus, J.; Kumar, A.; Kupco, A.; Kurča, T.; Kuzmin, V. A.; Lammers, S.; Lebrun, P.; Lee, H. S.; Lee, S. W.; Lee, W. M.; Lei, X.; Lellouch, J.; Li, D.; Li, H.; Li, L.; Li, Q. Z.; Lim, J. K.; Lincoln, D.; Linnemann, J.; Lipaev, V. V.; Lipton, R.; Liu, H.; Liu, Y.; Lobodenko, A.; Lokajicek, M.; Lopes de Sa, R.; Luna-Garcia, R.; Lyon, A. L.; Maciel, A. K. A.; Madar, R.; Magaña-Villalba, R.; Malik, S.; Malyshev, V. L.; Mansour, J.; Martínez-Ortega, J.; McCarthy, R.; McGivern, C. L.; Meijer, M. M.; Melnitchouk, A.; Menezes, D.; Mercadante, P. G.; Merkin, M.; Meyer, A.; Meyer, J.; Miconi, F.; Mondal, N. K.; Mulhearn, M.; Nagy, E.; Narain, M.; Nayyar, R.; Neal, H. A.; Negret, J. P.; Neustroev, P.; Nguyen, H. T.; Nunnemann, T.; Orduna, J.; Osman, N.; Osta, J.; Pal, A.; Parashar, N.; Parihar, V.; Park, S. K.; Partridge, R.; Parua, N.; Patwa, A.; Penning, B.; Perfilov, M.; Peters, Y.; Petridis, K.; Petrillo, G.; Pétroff, P.; Pleier, M. -A.; Podstavkov, V. M.; Popov, A. V.; Prewitt, M.; Price, D.; Prokopenko, N.; Qian, J.; Quadt, A.; Quinn, B.; Ratoff, P. N.; Razumov, I.; Ripp-Baudot, I.; Rizatdinova, F.; Rominsky, M.; Ross, A.; Royon, C.; Rubinov, P.; Ruchti, R.; Sajot, G.; Sánchez-Hernández, A.; Sanders, M. P.; Santos, A. S.; Savage, G.; Savitskyi, M.; Sawyer, L.; Scanlon, T.; Schamberger, R. D.; Scheglov, Y.; Schellman, H.; Schwanenberger, C.; Schwienhorst, R.; Sekaric, J.; Severini, H.; Shabalina, E.; Shary, V.; Shaw, S.; Shchukin, A. A.; Simak, V.; Skubic, P.; Slattery, P.; Smirnov, D.; Snow, G. R.; Snow, J.; Snyder, S.; Söldner-Rembold, S.; Sonnenschein, L.; Soustruznik, K.; Stark, J.; Stoyanova, D. A.; Strauss, M.; Suter, L.; Svoisky, P.; Titov, M.; Tokmenin, V. V.; Tsai, Y. -T.; Tsybychev, D.; Tuchming, B.; Tully, C.; Uvarov, L.; Uvarov, S.; Uzunyan, S.; Van Kooten, R.; van Leeuwen, W. M.; Varelas, N.; Varnes, E. W.; Vasilyev, I. A.; Verkheev, A. Y.; Vertogradov, L. S.; Verzocchi, M.; Vesterinen, M.; Vilanova, D.; Vokac, P.; Wahl, H. D.; Wang, M. H. L. S.; Warchol, J.; Watts, G.; Wayne, M.; Weichert, J.; Welty-Rieger, L.; Williams, M. R. J.; Wilson, G. W.; Wobisch, M.; Wood, D. R.; Wyatt, T. R.; Xie, Y.; Yamada, R.; Yang, S.; Yasuda, T.; Yatsunenko, Y. A.; Ye, W.; Ye, Z.; Yin, H.; Yip, K.; Youn, S. W.; Yu, J. M.; Zennamo, J.; Zhao, T. G.; Zhou, B.; Zhu, J.; Zielinski, M.; Zieminska, D.; Zivkovic, L.

    2014-12-01

    We measure the direct mi>Cmi>mi>P>-violating parameter mi>Ami>mi>Cmi>mi>Pmi> for the decay of the charged charm meson, mi>Dmi>+mi>Kmi>-mi>πmi>+mi>πmi>+ (and charge conjugate), using the full 10.4 mi>fbmi>-1 sample of mi>p>mi>p>¯ collisions at mi>smi>=1.96 mi>TeVmi> collected by the D0 detector at the Fermilab Tevatron collider. We extract the raw reconstructed charge asymmetry by fitting the invariant mass distributions for the sum and difference of charge-specific samples. This quantity is then corrected for detector-related asymmetries using data-driven methods and for possible physics asymmetries (from mi>B>mi>D

  7. P.O. Box 117, Oak Ridge, TN 37831

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Box 117, Oak Ridge, TN 37831 g (865) 241-8893 g IVsurveys@orau.org On the Web: www.orau.orgenvironmental-assessments-health-physics Oak Ridge Associated Universities (ORAU) is a...

  8. SC FPD 360 Mentoring | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    SC FPD 360 Mentoring Project Assessment (OPA) OPA Home About Project Management SC Projects Other Links SC Federal Project Directors (FPD) and FPD Resources Certified Federal ...

  9. New Ellenton, SC SRS

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Aiken Hwy 19 S New Ellenton, SC SRS Road 2 barricade SRS Road 1 Directions from Aiken: Take Hwy. 19 S out of Aiken, through New Ellenton, onto the SRS. Bear right onto SRS Road 1 and continue on Road 1 past a turn-off onto Road 1-A. Continue on Road 1 until you reach a sign indicating "SRS Visitor's Control" and "SRS Operations Center"--turn left into the large parking lot. Your sponsor will meet you at the front of the badge office. SRS Road 1-A SREL SRS "Visitor's

  10. DOE_StrategicPlan_Draft_tn.jpg | OSTI, US Dept of Energy Office of

    Office of Scientific and Technical Information (OSTI)

    Scientific and Technical Information DOE_StrategicPlan_Draft_tn

  11. Origin State>> CA CA ID ID ID IL KY MD NM NM NV NY NY OH TN

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NM NM NV NY NY OH TN TN TN, WA, CA TN TN TN TN TX Total Shipments by Route Lawrence Livermore National Laboratory General Atomics Advanced Mixed Waste Treatment Project Batelle Energy Alliance Idaho National Laboratory Argonne National Laboratory Paducah Gaseous Diffusion Plant Aberdeen Proving Ground Los Alamos National Laboratory Sandia National Laboratory National Security Technologies Brookhaven National Laboratory West Valley Environmental Services Portsmouth Gaseous Diffusion Plant

  12. NERSC Training at SC11

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NERSC Training at SC11 SC11Logo NERSC staff will be participating in a number of tutorials Nov. 13-14 at SC11 in Seattle. S10: Scaling to Petascale and Beyond: Performance Analysis and Optimization of Applications Scaling to Petascale and Beyond: Performance Analysis and Optimization of Applications Read More » S13: HPC Archive Solutions Made Simple Scaling to Petascale and Beyond: Performance Analysis and Optimization of Applications Read More » M08: Intro to PGAS (UPC and CAF) and Hybrid

  13. NERSC Training at SC12

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NERSC Training at SC12 SC12LogoGreytextsm2 NERSC staff will be participating in a number of tutorials Nov. 11-12 at SC12 in Salt Lake City including the following. Intro to PGAS (UPC and CAF) and Hybrid for Multicore Programming Intro to PGAS (UPC and CAF) and Hybrid for Multicore Programming Read More » Parallel I/O in Practice Parallel I/O in Practice Read More » Using Application Proxies for Co-design of Future HPC Computer Systems and Applications Intro to PGAS (UPC and CAF) and Hybrid

  14. SC Federal Project Directors | U.S. DOE Office of Science (SC...

    Office of Science (SC) Website

    Federal Project Directors (FPD) and FPD Resources Project Assessment (OPA) OPA Home About Project Management SC Projects Other Links SC Federal Project Directors (FPD) and FPD ...

  15. Mission & Functions | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    ... Provides management oversight of SC international program activities. Ensures they are ... Ensures integration of SC Program Office efforts. Also ensures that SC research programs ...

  16. Norris-lake-big-ridge-tn1_caption.jpg | OSTI, US Dept of Energy Office of

    Office of Scientific and Technical Information (OSTI)

    Scientific and Technical Information Norris-lake-big-ridge-tn1_caption

  17. REPLY TO Al-TN OF: EM-421 SUBJECT:

    Office of Legacy Management (LM)

    ;;;;!r;; c"/ I%- , 2.1 + 2- llnited States Government Department of Energy memorandum Fw?fw --&a Gt3 .I\ DATE: Af'R 8 1991 REPLY TO Al-TN OF: EM-421 SUBJECT: Elimination of the Magnus Brass Manufacturing Company from FUSRAP TO: The File The Magnus Brass Manufacturing Company Sites are hereby eliminated from consideration in the Department of Energy's Formerly Utilized Sites Remedial Action Program (FUSRAP). The Department of Energy does not have the authority under the Atomic Energy Act

  18. SC

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    Community Longleaf Pine D Mixed PineHardwood D Sandhills Scrub OakPine o Monitoring Wells Road Utility ROW * Wastesites 1221 Other Set-Asides r:;c::J Areas B Hydric Soils D...

  19. Connect with SC | U.S. DOE Office of Science (SC)

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    Connect with SC About About Home Organization Budget Field Operations Federal Advisory Committees History Scientific and Technical Information Honors & Awards Jobs Brochures, Logos, & Information Resources Brochures Fact Sheets SC Logos Newsletters Connect with SC Contact Contact Information Office of Science U.S. Department of Energy 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5430 Brochures, Logos, & Information Resources Connect with SC Print Text Size: A A A

  20. shaleusa5.pdf

    Gasoline and Diesel Fuel Update (EIA)

    ... NY PA NJ OH DC DE WV MD KY VA NC TN SC MI CANADA 2 0 0 1 0 0 Marcellus Shale Gas Play, Appalachian Basin Source: US Energy Information Administration based on data from WVGES , PA ...

  1. Spectroscopic and ITC study of the conformational change upon Ca{sup 2+}-binding in TnC C-lobe and TnI peptide complex from Akazara scallop striated muscle

    SciTech Connect (OSTI)

    Yumoto, Fumiaki; Tanaka, Hiroyuki; Nagata, Koji; Miyauchi, Yumiko; Miyakawa, Takuya; Ojima, Takao; Tanokura, Masaru

    2008-04-25

    Akazara scallop (Chlamys nipponensis akazara) troponin C (TnC) of striated adductor muscle binds only one Ca{sup 2+} ion at the C-terminal EF-hand motif (Site IV), but it works as the Ca{sup 2+}-dependent regulator in adductor muscle contraction. In addition, the scallop troponin (Tn) has been thought to regulate muscle contraction via activating mechanisms that involve the region spanning from the TnC C-lobe (C-lobe) binding site to the inhibitory region of the TnI, and no alternative binding of the TnI C-terminal region to TnC because of no similarity between second TnC-binding regions of vertebrate and the scallop TnIs. To clarify the Ca{sup 2+}-regulatory mechanism of muscle contraction by scallop Tn, we have analyzed the Ca{sup 2+}-binding properties of the complex of TnC C-lobe and TnI peptide, and their interaction using isothermal titration microcalorimetry, nuclear magnetic resonance, circular dichroism, and gel filtration chromatography. The results showed that single Ca{sup 2+}-binding to the Site IV leads to a structural transition not only in Site IV but also Site III through the structural network in the C-lobe of scallop TnC. We therefore assumed that the effect of Ca{sup 2+}-binding must lead to a change in the interaction mode between the C-lobe of TnC and the TnI peptide. The change should be the first event of the transmission of Ca{sup 2+} signal to TnI in Tn ternary complex.

  2. Room-temperature elastic constants of Sc and ScD[sub 0. 18

    SciTech Connect (OSTI)

    Leisure, R.G. ); Schwarz, R.B.; Migliori, A.; Lei, M. )

    1993-07-01

    The complete set of elastic constants for Sc and ScD[sub 0.18] has been measured at room temperature. The results show that the addition of hydrogen to this rare-earth metal has a qualitatively different effect than the addition of hydrogen to transition metals such as palladium, vanadium, niobium, and tantalum. In the case of Sc all five elastic constants increase with the addition of hydrogen. The bulk modulus for ScD[sub 0.18] is 9.5% higher than that for Sc. The Debye temperature computed from the room-temperature elastic constants is 355 K for Sc and 371 K for ScD[sub 0.18].

  3. Administration | U.S. DOE Office of Science (SC)

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    Administration Human Resources and Administration (HRA) HRA Home About Human Resources Administration SC Correspondence Control Center (SC CCC) Contact Information Human Resources...

  4. Human Resources | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Human Resources Human Resources and Administration (HRA) HRA Home About Human Resources Administration SC Correspondence Control Center (SC CCC) Contact Information Human Resources...

  5. China SC Exact Equipment Co LTD | Open Energy Information

    Open Energy Info (EERE)

    SC Exact Equipment Co LTD Jump to: navigation, search Name: China SC Exact Equipment Co., LTD Place: Shenzhen, Guangdong Province, China Zip: 518125 Sector: Solar Product:...

  6. Other Links | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Other Links Project Assessment (OPA) OPA Home About Project Management SC Projects Other Links SC Federal Project Directors (FPD) and FPD Resources Contact Information Project ...

  7. Real-time sub-<mi>>ngstrom...

    Office of Scientific and Technical Information (OSTI)

    Real-time sub-<mi>>ngstrom imaging of reversible and irreversible conformations in rhodium catalysts and graphene Kisielowski, Christian; Wang,...

  8. Brownfield to Brightfield Initiative in Oak Ridge, TN - 12346

    SciTech Connect (OSTI)

    Hough, Gil; Fairless, Chad

    2012-07-01

    Experience characterizing, permitting, and restoring 'Brownfield' sites-government or industrial sites with restricted future use due to the presence or potential presence of hazardous substances, pollutants, or contaminants-is being leveraged to identify opportunities for redevelopment into solar power generating facilities which, in this context, are called 'Brightfields'. Brownfield sites offer the expansive land necessary for large photovoltaic (PV) solar farms, but require an in-depth working knowledge of complicated regulatory restrictions and environmental constraints to develop them. As a part of the effort to identify opportunities for redevelopment of Brownfield sites for solar applications, a technical guide, was composed specifically for the development of solar generation on restricted use sites. The basis of the technical guide gives specific consideration to environmental requirements and installation methods breaking that into three areas for assessing: 1) levels of contamination, 2) ground penetration requirements, and 3) the requirements for aesthetics and maintenance. Brightfield projects are underway to support the technical guide and expand re-industrialization efforts for the former DOE Gaseous Diffusion Plant in Oak Ridge, TN. There are exciting opportunities to turn Brownfields into Brightfield solar energy solutions for meeting the future renewable energy needs of our country. Brownfields that offer the large surface area required for solar PV farms coupled with the technical guide for the installation of solar farms on restricted use sites supports efforts to develop the solar capacities and expertise to tap this future market. The initial projects designed following the technical guide will provide verification of the installation requirements and beneficial reuse of restricted use sites. (authors)

  9. File:USDA-CE-Production-GIFmaps-TN.pdf | Open Energy Information

    Open Energy Info (EERE)

    TN.pdf Jump to: navigation, search File File history File usage Tennessee Ethanol Plant Locations Size of this preview: 776 600 pixels. Full resolution (1,650 1,275...

  10. Y-12 and East TN Public Broadcasting System ? A Nuclear Family...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    - A Nuclear Family Video Miniseries The fourth and final episode of A Nuclear Family: Y-12 National Security Complex documentary film miniseries is complete and East TN PBS is...

  11. SC e-journals About/FAQ

    Office of Scientific and Technical Information (OSTI)

    Q. What is the 'Web of Science' search feature? A. Web of Science, a product of Thomson Reuters, is also available via the SC e-journals home page. Web of Science is one of the ...

  12. sc0013735-psi | netl.doe.gov

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of Terrain from Unmanned Aircraft Systems (UASs) Last Reviewed 632016 DE-SC0013735 Goal This project will develop a conceptual design for an unmanned aerial system-based ...

  13. sc0006378 | netl.doe.gov

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Process for Carbon Capture in Existing Coal-Fired Power Plants Project No.: DE-SC0006378 In ... low-quality energy from the power plant, which is typically released into the ...

  14. Summary - Environmental Management Waste Management Facility (EMWMF) at Oak Ridge, TN

    Office of Environmental Management (EM)

    Oak Ridge, TN EM Project: EM Waste Management Facility ETR Report Date: February 2008 ETR-11 United States Department of Energy Office of Environmental Management (DOE-EM) External Technical Review of Environmental Management Waste Management Facility (EMWMF) at Oak Ridge, TN Why DOE-EM Did This Review The Environmental Management Waste Management Facility (EMWMF) is a land disposal facility for wastes generated by environmental restoration activities being conducted at the US Department of

  15. Summary - Major Risk Factors Integrated Facility Disposition Project (IFDP) Oak Ridge, TN

    Office of Environmental Management (EM)

    & ORNL, Oak Ridge, TN EM Project: Integrated Facility Disposition Project (IFDP) ETR Report Date: August 2008 ETR-15 United States Department of Energy Office of Environmental Management (DOE-EM) External Technical Review of the Major Risk Factors Integrated Facility Disposition Project (IFDP) Oak Ridge, TN Why DOE-EM Did This Review Approximately two million pounds of mercury are unaccounted for at Y-12 and mercury contamination has been detected in both soils and groundwater. The IFDP will

  16. DOE-NNSA and State of TN Participate in Regional CAPSTONE Exercise | Y-12

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    National Security Complex DOE-NNSA and State of TN ... DOE-NNSA and State of TN Participate in Regional CAPSTONE Exercise Posted: June 2, 2014 - 8:21am The U.S. Department of Energy's National Nuclear Security Administration's Radiological Assistance Program, and the State of Tennessee's Offices of Emergency Management & Division of Radiological Health will participate in a Regional CAPSTONE exercise with activities to be conducted by Field Monitoring Teams in the public sector on

  17. DOE - Office of Legacy Management -- Oak Ridge Gaseous Diffusion Plant - TN

    Office of Legacy Management (LM)

    02 Oak Ridge Gaseous Diffusion Plant - TN 02 FUSRAP Considered Sites Site: Oak Ridge Gaseous Diffusion Plant (TN.02 ) Designated Name: Alternate Name: Location: Evaluation Year: Site Operations: Site Disposition: Radioactive Materials Handled: Primary Radioactive Materials Handled: Radiological Survey(s): Site Status: Also see http://www.mbe.doe.gov/me70/manhattan/come_through.htm Documents Related to Oak Ridge Gaseous Diffusion Plant

  18. DOE - Office of Legacy Management -- Union Carbide and Carbon Co - TN 10

    Office of Legacy Management (LM)

    Carbide and Carbon Co - TN 10 FUSRAP Considered Sites Site: Union Carbide and Carbon Co (TN.10) Designated Name: Alternate Name: Location: Evaluation Year: Site Operations: Site Disposition: Radioactive Materials Handled: Primary Radioactive Materials Handled: Radiological Survey(s): Site Status: This site is one of a group of 5 FUSRAP considered sites for which records are available that provide a reasonably complete historical account of their operations and relationship, if any, with MED/AEC

  19. DOE - Office of Legacy Management -- W R Grace - Erwin - TN 05

    Office of Legacy Management (LM)

    - Erwin - TN 05 FUSRAP Considered Sites Site: W R Grace - Erwin (TN.05) Designated Name: Alternate Name: Location: Evaluation Year: Site Operations: Site Disposition: Radioactive Materials Handled: Primary Radioactive Materials Handled: Radiological Survey(s): Site Status: This site is one of a group of 5 FUSRAP considered sites for which records are available that provide a reasonably complete historical account of their operations and relationship, if any, with MED/AEC operations. However,

  20. Mi GmbH | Open Energy Information

    Open Energy Info (EERE)

    Mi GmbH Jump to: navigation, search Name: Mi GmbH Place: Switzerland Zip: CH-6340 Sector: Solar Product: Baar-based manufacturer and distributor of fruit juices. The firm is also...

  1. miRNAs in brain development

    SciTech Connect (OSTI)

    Petri, Rebecca; Malmevik, Josephine; Fasching, Liana; Åkerblom, Malin; Jakobsson, Johan

    2014-02-01

    MicroRNAs (miRNAs) are small, non-coding RNAs that negatively regulate gene expression at the post-transcriptional level. In the brain, a large number of miRNAs are expressed and there is a growing body of evidence demonstrating that miRNAs are essential for brain development and neuronal function. Conditional knockout studies of the core components in the miRNA biogenesis pathway, such as Dicer and DGCR8, have demonstrated a crucial role for miRNAs during the development of the central nervous system. Furthermore, mice deleted for specific miRNAs and miRNA-clusters demonstrate diverse functional roles for different miRNAs during the development of different brain structures. miRNAs have been proposed to regulate cellular functions such as differentiation, proliferation and fate-determination of neural progenitors. In this review we summarise the findings from recent studies that highlight the importance of miRNAs in brain development with a focus on the mouse model. We also discuss the technical limitations of current miRNA studies that still limit our understanding of this family of non-coding RNAs and propose the use of novel and refined technologies that are needed in order to fully determine the impact of specific miRNAs in brain development. - Highlights: • miRNAs are essential for brain development and neuronal function. • KO of Dicer is embryonically lethal. • Conditional Dicer KO results in defective proliferation or increased apoptosis. • KO of individual miRNAs or miRNA families is necessary to determine function.

  2. doe-sc-arm-tr-162

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    SC-ARM-TR-162 Particle-into-Liquid Sampler Instrument Handbook TB Watson March 2016 DOE/SC-ARM-TR-162 DISCLAIMER This report was prepared as an account of work sponsored by the U.S. Government. Neither the United States nor any agency thereof, nor any of their employees, makes any warranty, express or implied, or assumes any legal liability or responsibility for the accuracy, completeness, or usefulness of any information, apparatus, product, or process disclosed, or represents that its use

  3. DOE - Office of Legacy Management -- Michigan Velsicol Chemical Corp - MI

    Office of Legacy Management (LM)

    03 Michigan Velsicol Chemical Corp - MI 03 FUSRAP Considered Sites Site: MICHIGAN [VELSICOL] CHEMICAL CORP. (MI.03 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: Velsicol Chemical Corp. MI.03-1 Location: St. Louis , Michigan MI.03-2 Evaluation Year: Circa 1987 MI.03-3 Site Operations: Rare earth processing facility. MI.03-2 Site Disposition: Eliminated - No Authority - NRC survey MI.03-3 Radioactive Materials Handled: Yes Primary Radioactive

  4. DOE - Office of Legacy Management -- Star Cutter Corp - MI 15

    Office of Legacy Management (LM)

    Star Cutter Corp - MI 15 FUSRAP Considered Sites Site: STAR CUTTER CORP. (MI.15) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Farmington , Michigan MI.15-1 Evaluation Year: 1991 MI.15-2 Site Operations: Performed a one time uranium slug drilling operation test in 1956. MI.15-3 MI.15-1 Site Disposition: Eliminated - Potential for contamination considered remote based on limited scope and quantity of materials handled MI.15-2 Radioactive

  5. Summary - Mitigation and Remediation of Mercury Contamination at the Y-12 Plant, Oak Ridge, TN

    Office of Environmental Management (EM)

    Oak Ridge, TN EM Project: Mitigation/Remediation of Hg ETR Report Date: April 2008 ETR-13 United States Department of Energy Office of Environmental Management (DOE-EM) External Technical Review of the Mitigation and Remediation of Mercury Contamination at the Y-12 Plant, Oak Ridge, TN Why DOE-EM Did This Review From 1953 to 1983, ~240,000 pounds of mercury (Hg) were released to the East Fork Popular Creek during the operation of the Y-12 Plant. In 1963, direct systematic releases of mercury

  6. SC web highlight (Technical Report) | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    Technical Report: SC web highlight Citation Details In-Document Search Title: SC web highlight Authors: Perez, F ; Kemp, A ; Divol, L ; Chen, C ; Patel, P K Publication Date: ...

  7. SC web highlight (Technical Report) | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    Technical Report: SC web highlight Citation Details In-Document Search Title: SC web highlight You are accessing a document from the Department of Energy's (DOE) SciTech ...

  8. SC11 Education Program Applications due July 31

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    SC11 Education Program Applications due July 31 SC11 Education Program Applications due July 31 June 9, 2011 by Francesca Verdier Applications for the Education Program are now ...

  9. FY 2014 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    FY 2014 Energy and Water Development Appropriations House Senate Conference Enacted Bill H. R. 2609 .pdf file (189KB) (SC Only) .pdf file (97KB) S. 1245 .pdf file (235KB) (SC Only) ...

  10. REPLY TO AlTN OF: W-421 (W. A. W

    Office of Legacy Management (LM)

    QOEF 13254 i.3891 EFG iO7W United- states Government bemoranduin DATE: f-uG 3, 9 19g4 REPLY TO AlTN OF: W-421 (W. A. W illiams, 427-1719) SUBJECT: Elimination of the Sites from ...

  11. EA-1514: Proposed Conveyance of Parcel ED-6 to the City of Oak Ridge, TN

    Broader source: Energy.gov [DOE]

    This Environmental Assessment was prepared for the conveyance of approximately 336 acres of excess property (i.e., property not needed to fulfill DOE current or foreseeable future requirements) known as Parcel ED-6 to the city of Oak Ridge, TN.

  12. Magnetic order and electronic structure of 5d3 double perovskite Sr2ScOsO6

    SciTech Connect (OSTI)

    Calder, Stuart A; Morrow, Ryan; Taylor, Alice E; Lumsden, Mark D; Woodward, Patrick; Christianson, Andrew D; Singh, David J

    2015-01-01

    The magnetic susceptibility, crystal and magnetic structures, and electronic structure of double perovskite Sr2ScOsO6 are reported. Using both neutron and x-ray powder diffraction we find that the crystal structure is monoclinic P21/n from 3.5 to 300 K. Magnetization measurements indicate an antiferromagnetic transition at TN=92 K, one of the highest transition temperatures of any double perovskite hosting only one magnetic ion. Type I antiferromagnetic order is determined by neutron powder diffraction, with an Os moment of only 1.6(1) muB, close to half the spin-only value for a crystal field split 5d electron state with t2g^3 ground state. Density functional calculations show that this reduction is largely the result of strong Os-O hybridization, with spin-orbit coupling responsible for only a ~0.1 muB reduction in the moment.

  13. Gerber-HPC-SC11.pptx

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    to Petascale and Beyond: Performance Analysis and Optimization of Applications R. Glenn Brook, U. Tennessee Don Frederick, LLNL Richard Gerber, NERSC / Berkley Lab Jeff Larkin, Cray, Inc. http://www.nersc.gov/users/training/nersc-training-events/sc11/s10/ * Design Considerations - 8:30 - Introduction to Petascale Systems - 30 minutes - Richard Gerber - 9:00 - HPC Communication - 45 minutes - Glenn Brook - 9:45 - Break - 10:00 - HPC IO & Lustre File Systems - Richard Gerber, 50 minutes -

  14. sc0011869 | netl.doe.gov

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    combustion Integrated Membrane Reactor for Pre-Combustion CO2 Capture Project No.: DE-SC0011869 In this Small Business Innovation Research/Small Business Technology Transfer (SBIR/STTR) project, Techverse, Inc., in collaboration with Pall Corporation and Southern Research Institute (SRI), is developing a transformational ternary palladium (Pd)-alloy membrane-based process intensification technology for cost-effective pre-combustion CO2 capture. Process intensification combines the water-gas

  15. sc0013735-psi | netl.doe.gov

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    735-psi High Performance Airborne Laser Scanner for Routine Mapping of Terrain from Unmanned Aircraft Systems (UASs) Last Reviewed 6/3/2016 DE-SC0013735 Goal This project will develop a conceptual design for an unmanned aerial system-based laser scanner for aerial mapping that preserves the performance of larger systems flown on manned aircraft, but is small enough to be deployed on midsize unmanned aerial systems. This will enable more economical digital terrain mapping than manned systems. The

  16. DOE - Office of Legacy Management -- Wolverine Tube Division - MI 05

    Office of Legacy Management (LM)

    Wolverine Tube Division - MI 05 FUSRAP Considered Sites Site: Wolverine Tube Division (MI.05) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: Wolverine Tube Division of Calumet & Hecla Consolidated Copper Co. Star Tool Hermes Automotive Manufacturing Corporation MI.05-1 MI.05-2 Location: 1411 Central Avenue , Detroit , Michigan MI.05-3 Evaluation Year: 1990 MI.05-2 Site Operations: 1943 - Conducted research and development of methods for spinning

  17. DOE - Office of Legacy Management -- Adrian - MI 01

    Office of Legacy Management (LM)

    Adrian - MI 01 FUSRAP Considered Sites Adrian, MI Alternate Name(s): Bridgeport Brass Co. Special Metals Extrusion Plant Bridgeport Brass Company General Motors General Motors Company, Adrian MI.01-1 Location: 1450 East Beecher Street, Adrian, Michigan MI.01-3 Historical Operations: Performed uranium extrusion research and development and metal fabrication work for the AEC using uranium, thorium, and plutonium. MI.01-2 Eligibility Determination: Eligible MI.01-1 Radiological Survey(s):

  18. DOE - Office of Legacy Management -- Carboloy Co - MI 12

    Office of Legacy Management (LM)

    Carboloy Co - MI 12 FUSRAP Considered Sites Site: Carboloy Co. (MI.12 ) Eliminated from further consideration under FUSRAP - AEC licensed facility Designated Name: Not Designated Alternate Name: General Electric MI.12-1 Location: 11177 E. Eight Mile Road , Detroit , Michigan MI.12-1 MI.12-2 Evaluation Year: 1987-1991 MI.12-3 MI.12-4 MI.12-6 Site Operations: Turned-down the outer diameter of uranium metal slugs and conducted pilot plant scale operations for hot pressing uranium dioxide pellets

  19. N E R SC Annual Repor

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    E R SC Annual Repor t 2002 National Energ y Research Scientific Computing Center 2002 AN N U A L R E P O R T This work was supported by the Director, Office of Science, Office of Advanced Scientific Computing Research of the U.S. Department of Energy under Contract No. DE-AC 03-76SF00098. LBNL-51979, January 2003 T A B L E O F C O N T E N T S i i i Director's Perspective . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

  20. Spectroscopy of {sup 52,53}Sc

    SciTech Connect (OSTI)

    Bhattacharyya, S.; Rejmund, M.; Navin, A.; Gelin, M.; Mittig, W.; Mukherjee, G.; Rejmund, F.; Roussel-Chomaz, P.; Poves, A.; Theisen, Ch.

    2009-01-15

    Excited states of neutron-rich odd-A and odd-odd Sc isotopes, populated in deep inelastic multinucleon transfer reactions, induced by a {sup 238}U beam on a thin {sup 48}Ca target, have been identified. A strong feeding of both yrast and nonyrast states in such a reaction is illustrated using a combination of a large efficiency spectrometer and a {gamma} detector array. The structure of the populated states is interpreted in terms of the role of the valence proton and neutrons and compared to shell model calculations in the full pf shell.

  1. sc0010208 | netl.doe.gov

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Energy and Capital-Efficient Sorbent-Based CO2 Capture Project No.: DE-SC0010208 InnoSepra's two-bed laboratory testing unit (click to enlarge) In this Small Business Innovation Research (SBIR) project, InnoSepra LLC is evaluating the viability of their novel sorbent-based CO2 capture technology for cost-effective CO2 capture from coal-fired power plants. The technology utilizes physical sorbents in structured monolithic form to capture CO2 and will remove water and flue gas contaminants (i.e.,

  2. sc0013242-terves | netl.doe.gov

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    242-terves Swellable Proppants for In-Situ Well Stimulation Last Reviewed 6/3/2016 DE-SC0013242 Goal The goal of this project is to develop an "engineered ice" or "rusting rebar" proppant that can deliver large localized forces to fracture rock under high constraining forces, similar to how water freezing or rebar rusting cause fracture in rock and concrete structures. The overall objective of this project is to develop a new class of structural expandable proppant particles

  3. Completed Projects | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Completed Projects Project Assessment (OPA) OPA Home About Project Management SC Projects Review Dates (updated August 2016) Project Construction Photos Completed Projects Current Projects Other Links SC Federal Project Directors (FPD) and FPD Resources Contact Information Project Assessment U.S. Department of Energy SC-28/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-4840 F: (301) 903-8520 E: Email Us Project Construction Photos Completed Projects Print Text

  4. Ongoing Projects | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Current Projects Project Assessment (OPA) OPA Home About Project Management SC Projects Review Dates (updated August 2016) Project Construction Photos Completed Projects Current Projects Other Links SC Federal Project Directors (FPD) and FPD Resources Contact Information Project Assessment U.S. Department of Energy SC-28/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-4840 F: (301) 903-8520 E: Email Us Project Construction Photos Current Projects Print Text Size:

  5. Lessons Learned | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Lessons Learned Project Assessment (OPA) OPA Home About Project Management Processes and Procedures Cost & Contingency EDIA Escalation Rates Earned Value Management System (EVMS) Certifications Awards Lessons Learned Tools & Resources SC Projects Other Links SC Federal Project Directors (FPD) and FPD Resources Contact Information Project Assessment U.S. Department of Energy SC-28/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-4840 F: (301) 903-8520 E:

  6. About | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    About Project Assessment (OPA) OPA Home About Director Staff & Responsibilities Location Jobs Project Management SC Projects Other Links SC Federal Project Directors (FPD) and FPD Resources Contact Information Project Assessment U.S. Department of Energy SC-28/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-4840 F: (301) 903-8520 E: Email Us About Print Text Size: A A A FeedbackShare Page Click to enlarge photo. Enlarge Photo The Spallation Neutron Source and

  7. Escalation Rates | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Escalation Rates Project Assessment (OPA) OPA Home About Project Management Processes and Procedures Cost & Contingency EDIA Escalation Rates Earned Value Management System (EVMS) Certifications Awards Lessons Learned Tools & Resources SC Projects Other Links SC Federal Project Directors (FPD) and FPD Resources Contact Information Project Assessment U.S. Department of Energy SC-28/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-4840 F: (301) 903-8520 E:

  8. Jobs | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Jobs Project Assessment (OPA) OPA Home About Director Staff & Responsibilities Location Jobs Project Management SC Projects Other Links SC Federal Project Directors (FPD) and FPD Resources Contact Information Project Assessment U.S. Department of Energy SC-28/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-4840 F: (301) 903-8520 E: Email Us About Jobs Print Text Size: A A A FeedbackShare Page Current Open Federal Positions The Office of Project Assessment is

  9. DOE - Office of Legacy Management -- Oliver Corp - MI 11

    Office of Legacy Management (LM)

    Oliver Corp - MI 11 FUSRAP Considered Sites Site: OLIVER CORP. (MI.11 ) Eliminated from further consideration under FUSRAP - Referred to NRC Designated Name: Not Designated Alternate Name: Behnke Warehousing Incorporated MI.11-1 Location: 433 East Michigan Avenue , Battle Creek , Michigan MI.11-1 Evaluation Year: 1986 MI.11-4 Site Operations: Conducted production scale briquetting of green salt and magnesium blend under AEC license Nos. SNM-591, SUB-579, and C-3725. MI.11-1 MI.11-3 Site

  10. Mission & Functions | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    ... Represents SC and makes commitments for the Department in discussions and meetings with high-level government and private sector officials. Typical meetings may be with members of ...

  11. Mission & Functions | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    ... Represents SC and makes commitments for the Department in discussions and meetings with high-level government and private sector officials. Meetings are typically with members of ...

  12. OUT-OF-PLANE SHEAR BEHAVIOR OF SC COMPOSITE STRUCTURES

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    INTRODUCTION Steel-plate composite (SC) structures have been used to expedite ... Behavior of steel materials in the inelastic range up to fracture, iii. Interaction ...

  13. Jobs | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Jobs Human Resources and Administration (HRA) HRA Home About Director Biography Organization Chart .pdf file (26KB) Jobs Human Resources Administration SC Correspondence Control...

  14. Director Biography | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Director Biography Human Resources and Administration (HRA) HRA Home About Director Biography Organization Chart .pdf file (26KB) Jobs Human Resources Administration SC...

  15. About | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    About Human Resources and Administration (HRA) HRA Home About Director Biography Organization Chart .pdf file (26KB) Jobs Human Resources Administration SC Correspondence Control...

  16. Oregon Regions | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Oregon Regions National Science Bowl (NSB) NSB Home About High School High School ... WDTS Home Contact Information National Science Bowl U.S. Department of Energy SC-27 ...

  17. California Regions | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    California Regions National Science Bowl (NSB) NSB Home About High School Middle School ... WDTS Home Contact Information National Science Bowl U.S. Department of Energy SC-27 ...

  18. Idaho Regions | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Idaho Regions National Science Bowl (NSB) NSB Home About High School High School ... WDTS Home Contact Information National Science Bowl U.S. Department of Energy SC-27 ...

  19. California Regions | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    California Regions National Science Bowl (NSB) NSB Home About High School High School ... WDTS Home Contact Information National Science Bowl U.S. Department of Energy SC-27 ...

  20. Pennsylvania Regions | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Pennsylvania Regions National Science Bowl (NSB) NSB Home About High School Middle ... WDTS Home Contact Information National Science Bowl U.S. Department of Energy SC-27 ...

  1. Idaho Regions | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Idaho Regions National Science Bowl (NSB) NSB Home About High School Middle School ... WDTS Home Contact Information National Science Bowl U.S. Department of Energy SC-27 ...

  2. Washington Regions | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Regions National Science Bowl (NSB) NSB Home About High School Middle School Middle ... WDTS Home Contact Information National Science Bowl U.S. Department of Energy SC-27 ...

  3. Pennsylvania Regions | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Pennsylvania Regions National Science Bowl (NSB) NSB Home About High School High School ... WDTS Home Contact Information National Science Bowl U.S. Department of Energy SC-27 ...

  4. Florida Regions | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Florida Regions National Science Bowl (NSB) NSB Home About High School High School ... WDTS Home Contact Information National Science Bowl U.S. Department of Energy SC-27 ...

  5. Nebraska Regions | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Nebraska Regions National Science Bowl (NSB) NSB Home About High School High School ... WDTS Home Contact Information National Science Bowl U.S. Department of Energy SC-27 ...

  6. Illinois Regions | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Illinois Regions National Science Bowl (NSB) NSB Home About High School High School ... WDTS Home Contact Information National Science Bowl U.S. Department of Energy SC-27 ...

  7. Illinois Regions | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Illinois Regions National Science Bowl (NSB) NSB Home About High School Middle School ... WDTS Home Contact Information National Science Bowl U.S. Department of Energy SC-27 ...

  8. Projects | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Sustainability Contact Information Operations Program Management U.S. Department of Energy SC-33Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301)...

  9. December | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Advanced Scientific Computing Research U.S. Department of Energy SC-21Germantown Building ... Petaflop on Jaguar ALCF Helps Deliver "Green" Wind Turbines and Jet Engines Berkeley ...

  10. August | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Advanced Scientific Computing Research U.S. Department of Energy SC-21Germantown Building ... Grid Al Gore Explores Green Technologies at ORNL FACILITIESINFRASTRUCTURE... ...

  11. SC14 DOE Booth Presentations by NERSC, Berkeley Lab Staff

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    SC14 DOE Booth Presentations by NERSC, Berkeley Lab Staff SC14 DOE Booth Presentations by NERSC, Berkeley Lab Staff November 17, 2014 SC14logo2 At the DOE booth (#1939) during the SC14 conference this week, Berkeley Lab staff will give featured talks, present demonstrations and host roundtable discussions. Featured Talks "How Does the Internet Get Under the Ocean? Building ESnet's Transatlantic Extension," by Greg Bell, ESnet, 3-3:30 p.m., Tuesday, Nov. 18. Abstract: The Department of

  12. Kentucky Regions | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    National Science Bowl U.S. Department of Energy SC-27 Forrestal Building 1000 ... Regional High School Science Bowl Green County Greater Cincinnati Regional High ...

  13. Project Management | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Project Assessment (OPA) OPA Home About Project ... Rates Earned Value Management System (EVMS) Certifications ... Project Assessment U.S. Department of Energy SC-28...

  14. Resources | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Grants & Contracts Support U.S. Department of Energy SC-43... applicantrecipient communities to streamline the ... Research (SBIR) program is a highly competitive ...

  15. About INCITE | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    U.S. Department of Energy SC-21Germantown Building ... of Science's INCITE Program Over the past 30 years, ... To help the research communities fully tap into the ...

  16. NERSC Scientists Contribute to SC14 Technical Program

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Scientists Contribute to SC14 Technical Program NERSC Scientists Contribute to SC14 Technical Program November 17, 2014 SC14logo3 Here's a look at the various talks, presentations, tutorials and demos that NERSC and other Berkeley Lab staff will be participating in during SC14: Invited Speaker Usable Exascale and Beyond Moore's Law, Horst Simon, Lab Directorate. 3:30-4:15 p.m. Tuesday, Nov. 18, New Orleans Theater. Papers A Computation- And Communication-Optimal Parallel Direct 3-Body Algorithm,

  17. About | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    It applies proven methodologies and industry-standard practices to emerging business requirements. Its enterprise IT services reach all of the SC customers and include desktop and ...

  18. The NuMI Neutrino Beam

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Adamson, P.; Anderson, K.; Andrews, M.; Andrews, R.; Anghel, I.; Augustine, D.; Aurisano, A.; Avvakumov, S.; Ayres, D. S.; Baller, B.; et al

    2015-10-20

    Our paper describes the hardware and operations of the Neutrinos at the Main Injector (NuMI) beam at Fermilab. It elaborates on the design considerations for the beam as a whole and for individual elements. The most important part of our design details pertaining to individual components is described. Beam monitoring systems and procedures, including the tuning and alignment of the beam and NuMI long-term performance, are also discussed.

  19. DOE - Office of Legacy Management -- Detrex Corp - MI 10

    Office of Legacy Management (LM)

    Detrex Corp - MI 10 FUSRAP Considered Sites Site: Detrex Corp. (MI.10 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Detroit , Michigan MI.10-1 Evaluation Year: 1987 MI.10-2 Site Operations: Conducted experimental runs relative to pickling/degreasing of one handful of uranium turnings MI.10-1 Site Disposition: Eliminated - Potential for contamination considered remote due to small quantity of material handled - There is no

  20. DOE - Office of Legacy Management -- Savannah River Swamp - SC 01

    Office of Legacy Management (LM)

    Savannah River Swamp - SC 01 FUSRAP Considered Sites Site: Savannah River Swamp (SC.01 ) Designated Name: Alternate Name: Location: Evaluation Year: Site Operations: Site Disposition: Radioactive Materials Handled: Primary Radioactive Materials Handled: Radiological Survey(s): Site Status: Also see http://www.srs.gov/general/pubs/ERsum/2001Reportpdfs/chapter10ar.pdf Documents Related to Savannah River Swamp

  1. Magnetic order and electronic structure of 5d3 double perovskite Sr2ScOsO6

    SciTech Connect (OSTI)

    Taylor, A. E.; Morrow, R.; Singh, D. J.; Calder, S.; Lumsden, M. D.; Woodward, P. M.; Christianson, A. D.

    2015-03-01

    The magnetic susceptibility, crystal and magnetic structures, and electronic structure of double perovskite Sr2ScOsO6 are reported. Using both neutron and x-ray powder diffraction we find that the crystal structure is monoclinic P21/n from 3.5 to 300 K. Magnetization measurements indicate an antiferromagnetic transition at TN=92 K, one of the highest transition temperatures of any double perovskite hosting only one magnetic ion. Type I antiferromagnetic order is determined by neutron powder diffraction, with an Os moment of only 1.6(1) muB, close to half the spin-only value for a crystal field split 5d electron state with t2g^3 ground state. Density functional calculations show that this reduction is largely the result of strong Os-O hybridization, with spin-orbit coupling responsible for only a ~0.1 muB reduction in the moment.

  2. DOE - Office of Legacy Management -- Naval Ordnance Plant - MI...

    Office of Legacy Management (LM)

    Eliminated from further consideration under FUSRAP - Referred to DoD for action Designated ... MI.0-03-1 Site Disposition: Eliminated - No Authority - Referred to DoD MI.0-03-1 ...

  3. Location | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Location Project Assessment (OPA) OPA Home About Director Staff & Responsibilities Location Jobs Project Management SC Projects Other Links SC Federal Project Directors (FPD) and FPD Resources Contact Information Project Assessment U.S. Department of Energy SC-28/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-4840 F: (301) 903-8520 E: Email Us About Location Print Text Size: A A A FeedbackShare Page The Office of Project Assessment is located at: Room #D-222

  4. About | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    About Ames Site Office (AMSO) AMSO Home About Organization Chart .pdf file (100KB) Federal Stewardship Internal Site Office Operations Jobs Projects Contract Management NEPA Documents Resources Contact Information Ames Site Office U.S. Department of Energy 9800 S. Cass Avenue Argonne, IL 60439 P: (630) 252-6167 F: (630) 252-2855 About Print Text Size: A A A FeedbackShare Page AMSO is a SC-line management organization that reports to the Deputy Director for Field Operations for SC (SC-3). Within

  5. miR-132 and miR-212 are increased in pancreatic cancer and target the retinoblastoma tumor suppressor

    SciTech Connect (OSTI)

    Park, Jong-Kook; Henry, Jon C.; Jiang, Jinmai; Esau, Christine; Gusev, Yuriy; Lerner, Megan R.; Postier, Russell G.; Brackett, Daniel J.; Schmittgen, Thomas D.

    2011-03-25

    Research highlights: {yields} The expression of miR-132 and miR-212 are significantly increased in pancreatic cancer. {yields} miR-132 and miR-212 target the tumor suppressor pRb, resulting in enhanced proliferation. {yields} miR-132 and miR-212 expression is increased by a {beta}2 adrenergic receptor agonist, suggesting a novel mechanism for pancreatic cancer progression. -- Abstract: Numerous microRNAs (miRNAs) are reported as differentially expressed in cancer, however the consequence of miRNA deregulation in cancer is unknown for many miRNAs. We report that two miRNAs located on chromosome 17p13, miR-132 and miR-212, are over-expressed in pancreatic adenocarcinoma (PDAC) tissues. Both miRNAs are predicted to target the retinoblastoma tumor suppressor, Rb1. Validation of this interaction was confirmed by luciferase reporter assay and western blot in a pancreatic cancer cell line transfected with pre-miR-212 and pre-miR-132 oligos. Cell proliferation was enhanced in Panc-1 cells transfected with pre-miR-132/-212 oligos. Conversely, antisense oligos to miR-132/-212 reduced cell proliferation and caused a G{sub 2}/M cell cycle arrest. The mRNA of a number of E2F transcriptional targets were increased in cells over expressing miR-132/-212. Exposing Panc-1 cells to the {beta}2 adrenergic receptor agonist, terbutaline, increased the miR-132 and miR-212 expression by 2- to 4-fold. We report that over-expression of miR-132 and miR-212 result in reduced pRb protein in pancreatic cancer cells and that the increase in cell proliferation from over-expression of these miRNAs is likely due to increased expression of several E2F target genes. The {beta}2 adrenergic pathway may play an important role in this novel mechanism.

  6. U.S. Energy Information Administration | Annual Coal Report 2014

    U.S. Energy Information Administration (EIA) Indexed Site

    5. Coal Consumers in the Manufacturing and Coke Sectors, 2014 Company Name Plant Location Top Ten Manufacturers American Crystal Sugar Co MN, ND Archer Daniels Midland IA, IL, MN, NE Carmeuse Lime Stone Inc AL, IN, KY, MI, OH, PA, TN, WI Cemex Inc AL, CA, CO, FL, GA, KY, OH, TN, TX Dakota Gasification Company ND Eastman Chemical Company TN Georgia-Pacific Consumer Products LP AL, GA, OK, VA, WI Holcim (US) Inc AL, CO, MD, MO, MT, OK, SC, TX, UT NewPage Corporation MD, MI, WI U S Steel

  7. “Nodal Gap” induced by the incommensurate diagonal spin density modulation in underdoped high- <mi>Tmi>c> superconductors

    SciTech Connect (OSTI)

    Zhou, Tao; Gao, Yi; Zhu, Jian -Xin

    2015-03-07

    Recently it was revealed that the whole Fermi surface is fully gapped for several families of underdoped cuprates. The existence of the finite energy gap along the <mi>d>-wave nodal lines (nodal gap) contrasts the common understanding of the <mi>d>-wave pairing symmetry, which challenges the present theories for the high-<mi>Tmi><mi>c>superconductors. Here we propose that the incommensurate diagonal spin-density-wave order can account for the above experimental observation. The Fermi surface and the local density of states are also studied. Our results are in good agreement with many important experiments in high-<mi>Tmi><mi>c>superconductors.

  8. Design of SC walls and slabs for impulsive loading

    SciTech Connect (OSTI)

    Varma, Amit H.

    2015-11-11

    Reinforced concrete (RC) structures have historically been the preferred choice for blast resistant structures because of their mass and the ductility provided by steel reinforcement. Steel-plate composite (SC) walls are a viable alternative to RC for protecting the infrastructure against explosive threats. SC structures consist of two steel faceplates with a plain concrete core between them. The steel faceplates are anchored to the concrete using stud anchors and connected to each other using tie bars. SC structures provide mass from the concrete infill and ductility from the continuous external steel faceplates. This dissertation presents findings and recommendations from experimental and analytical investigations of the performance of SC walls subjected to far-field blast loads.

  9. Washington Regions | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Regions National Science Bowl (NSB) NSB Home About High School High School Students High ... WDTS Home Contact Information National Science Bowl U.S. Department of Energy SC-27 ...

  10. Ohio Regions | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Ohio Regions National Science Bowl (NSB) NSB Home About High School High School Students ... WDTS Home Contact Information National Science Bowl U.S. Department of Energy SC-27 ...

  11. Sample Questions | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    National Science Bowl U.S. Department of Energy SC-27 Forrestal Building 1000 ... The files below should be used as a resource for sample questions, not sample answers. ...

  12. Texas Regions | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    National Science Bowl U.S. Department of Energy SC-27 Forrestal Building 1000 ... A&M Regional High School Science Bowl Tom Green County, Texas Texas A&M Regional High ...

  13. Texas Regions | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    National Science Bowl U.S. Department of Energy SC-27 Forrestal Building 1000 ... Regional Middle School Science Bowl Tom Green County Texas A&M Regional Middle School ...

  14. FY 2015 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    FY 2015 Energy and Water Development Appropriations House Senate Conference Enacted Bill H. R. 4923 .pdf file (228KB) (SC Only) .pdf file (182KB) Report H. Rpt. 113-486 .pdf file ...

  15. FY 2013 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    FY 2013 Energy and Water Development Appropriations House Senate Conference Enacted Bill H.R. 5325 .pdf file (218KB) (SC Only) .pdf file (99KB) Report H. Rpt. 112-462 .pdf file ...

  16. Newsletters | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Newsletters About About Home Organization Budget Field Operations Federal Advisory Committees History Scientific and Technical Information Honors & Awards Jobs Brochures, Logos, & Information Resources Brochures Fact Sheets SC Logos Newsletters Connect with SC Contact Contact Information Office of Science U.S. Department of Energy 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5430 Brochures, Logos, & Information Resources Newsletters Print Text Size: A A A

  17. Fact Sheets | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Fact Sheets About About Home Organization Budget Field Operations Federal Advisory Committees History Scientific and Technical Information Honors & Awards Jobs Brochures, Logos, & Information Resources Brochures Fact Sheets SC Logos Newsletters Connect with SC Contact Contact Information Office of Science U.S. Department of Energy 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5430 Brochures, Logos, & Information Resources Fact Sheets Print Text Size: A A A

  18. SC11 Education Program Applications due July 31

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    SC11 Education Program Applications due July 31 SC11 Education Program Applications due July 31 June 9, 2011 by Francesca Verdier Applications for the Education Program are now being accepted. Submission website: https://submissions.supercomputing.org Applications deadline: Sunday, July 31, 2011 Acceptance Notifications: Monday, August 22, 2011 The Education Program is hosting a four-day intensive program that will immerse participants in High Performance Computing (HPC) and Computational and

  19. Mariam Elsayed | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Mariam Elsayed Deputy Director for Science Programs Deputy Director Home Mission & Functions Deputy Director Biography Organization Staff Presentations & Testimony Federal Advisory Committees Committees of Visitors Contact Information Deputy Director for Science Programs U.S. Department of Energy SC-2/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5430 F: (202) 586-4120 E: Email Us U.S. Department of Energy SC-2/Germantown Building 1000 Independence Ave.,

  20. Management Homepage | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Home Management OM Home About Program Direction and Analysis Human Resources Advisory Office Administration Contact Information Management U.S. Department of Energy SC-48/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 More Information » Print Text Size: A A A FeedbackShare Page The Office of Management (OM) is the primary corporate resource for administrative management programs in the Office of Science. OM has responsibility for the development of SC-wide executive policy,

  1. Kevin Shaw | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Kevin Shaw Deputy Director for Science Programs Deputy Director Home Mission & Functions Deputy Director Biography Organization Staff Presentations & Testimony Federal Advisory Committees Committees of Visitors Contact Information Deputy Director for Science Programs U.S. Department of Energy SC-2/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5430 F: (202) 586-4120 E: Email Us U.S. Department of Energy SC-2/Germantown Building 1000 Independence Ave., SW

  2. Ray Irwin | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Ray Irwin Deputy Director for Science Programs Deputy Director Home Mission & Functions Deputy Director Biography Organization Staff Presentations & Testimony Federal Advisory Committees Committees of Visitors Contact Information Deputy Director for Science Programs U.S. Department of Energy SC-2/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5430 F: (202) 586-4120 E: Email Us U.S. Department of Energy SC-2/Germantown Building 1000 Independence Ave., SW

  3. Brochures | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Brochures About About Home Organization Budget Field Operations Federal Advisory Committees History Scientific and Technical Information Honors & Awards Jobs Brochures, Logos, & Information Resources Brochures Fact Sheets SC Logos Newsletters Connect with SC Contact Contact Information Office of Science U.S. Department of Energy 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5430 Brochures, Logos, & Information Resources Brochures Print Text Size: A A A FeedbackShare

  4. Characterization of function and regulation of miR-24-1 and miR-31

    SciTech Connect (OSTI)

    Sun Fenyong; Wang Jiayi; Pan Qiuhui; Yu Yongchun; Zhang Yue; Wan Yang; Wang Ju; Li Xiaoyan; Hong An

    2009-03-13

    To date, numerous microRNAs (miRNAs) have been discovered. However, the function of these miRNAs is largely unknown. While our knowledge of miRNA post-transcriptional processing has greatly expanded in recent years, we have a limited understanding of the regulation and transcription of miRNA genes. In this study, we characterized two BMP-2 upregulated miRNAs, miR-24-1 and miR-31, in mesenchymal stem cells and showed their opposing function in controlling cellular proliferation, and adipogenesis. Furthermore, we are the first to identify and characterize mouse intronic miR-23b{approx}27b{approx}24-1 and intergenic miR-31 genes. Moreover, we found that pri-miR-23b, pri-miR-27b, and pri-miR-24-1 are transcribed independently and their expression profiles are unique when cells are treated with BMP-2, even though they are located closely together.

  5. TN-68 Spent Fuel Transport Cask Analytical Evaluation for Drop Events

    SciTech Connect (OSTI)

    Shah, M. J.; Klymyshyn, Nicholas A.; Adkins, Harold E.; Koeppel, Brian J.

    2007-03-30

    The U.S. Nuclear Regulatory Commission (NRC) is responsible for licensing commercial spent nuclear fuel transported in casks certified by NRC under the Code of Federal Regulations (10 CFR), Title 10, Part 71 [1]. Both the International Atomic Energy Agency regulations for transporting radioactive materials [2, paragraph 727], and 10 CFR 71.73 require casks to be evaluated for hypothetical accident conditions, which includes a 9-meter (m) (30-ft) drop-impact event onto a flat, essentially unyielding, horizontal surface, in the most damaging orientation. This paper examines the behavior of one of the NRC certified transportation casks, the TN-68 [3], for drop-impact events. The specific area examined is the behavior of the bolted connections in the cask body and the closure lid, which are significantly loaded during the hypothetical drop-impact event. Analytical work to evaluate the NRC-certified TN-68 spent fuel transport cask [3] for a 9-m (30-ft) drop-impact event on a flat, unyielding, horizontal surface, was performed using the ANSYS® [4] and LS DYNA™ [5] finite-element analysis codes. The models were sufficiently detailed, in the areas of bolt closure interfaces and containment boundaries, to evaluate the structural integrity of the bolted connections under 9-m (30-ft) free-drop hypothetical accident conditions, as specified in 10 CFR 71.73. Evaluation of the cask for puncture, caused by a free drop through a distance of 1-m (40-in.) onto a mild steel bar mounted on a flat, essentially unyielding, horizontal surface, required by 10 CFR 71.73, was not included in the current work, and will have to be addressed in the future. Based on the analyses performed to date, it is concluded that, even though brief separation of the flange and the lid surfaces may occur under some conditions, the seals would close at the end of the drop events, because the materials remain elastic during the duration of the event.

  6. Michael Stone | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Michael Stone Albert Einstein Distinguished Educator Fellowship (AEF) Program Einstein Fellowship Home Eligibility Benefits Obligations How to Apply Key Dates Frequently Asked Questions Fellows Central Current Fellows Alumni Fellows Official AEF Logos Contact WDTS Home Current Fellows Michael Stone Print Text Size: A A A FeedbackShare Page Michael Stone Fellowship Placement: National Science Foundation Hometown: East Ridge, TN Michael Stone has taught at several high schools in Chattanooga,

  7. Contract Management | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Contract Management Oak Ridge National Laboratory Site Office (OSO) OSO Home About Projects Contract Management NEPA Documents Contact Information Oak Ridge National Laboratory Site Office U.S. Department of Energy Post Office Box 2008 Oak Ridge, TN 37831-6269 P: (865) 576-0710 Contract Management Print Text Size: A A A FeedbackShare Page OSO has contract oversight responsibilities for two major prime contractors: one with UT Battelle, the management and operating contractor for ORNL, and the

  8. Magnetic order and electronic structure of 5d3 double perovskite Sr2ScOsO6

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Taylor, A. E.; Morrow, R.; Singh, D. J.; Calder, S.; Lumsden, M. D.; Woodward, P. M.; Christianson, A. D.

    2015-03-01

    The magnetic susceptibility, crystal and magnetic structures, and electronic structure of double perovskite Sr2ScOsO6 are reported. Using both neutron and x-ray powder diffraction we find that the crystal structure is monoclinic P21/n from 3.5 to 300 K. Magnetization measurements indicate an antiferromagnetic transition at TN=92 K, one of the highest transition temperatures of any double perovskite hosting only one magnetic ion. Type I antiferromagnetic order is determined by neutron powder diffraction, with an Os moment of only 1.6(1) muB, close to half the spin-only value for a crystal field split 5d electron state with t2g^3 ground state. Density functional calculationsmore » show that this reduction is largely the result of strong Os-O hybridization, with spin-orbit coupling responsible for only a ~0.1 muB reduction in the moment.« less

  9. DOE - Office of Legacy Management -- Dow Chemical Co - Midland - MI 06

    Office of Legacy Management (LM)

    Midland - MI 06 FUSRAP Considered Sites Site: Dow Chemical Co. - Midland (MI.06 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Midland , Michigan MI.06-1 Evaluation Year: Circa 1987 MI.06-2 Site Operations: Conducted development work for production of magnesium-thorium alloys. MI.06-1 Site Disposition: Eliminated - AEC licensed site MI.06-1 MI.06-2 Radioactive Materials Handled: Yes Primary Radioactive Materials Handled:

  10. Experience with OpenMP for MADX-SC

    SciTech Connect (OSTI)

    D'Imperio, Nicholas; Montag, Christophe; Yu, Kwangmin; Kapin, Valery; McIntosh, Eric; Renshall, Harry; Schmidt, Frank

    2014-07-01

    MADX-SC allows the treatment of frozen space charge using beam-beam elements in a thin lattice, i.e. one can take advantage of the standard set-up of MAD-X lattices without the need for specialized codes for the space-charge (SC) evaluation. The idea is to simulate over many turns without the problem of noise as in the PIC SC codes. For the examples under study, like the PS and RHIC, it would be desirable to simulate up to 1 million turns or more. To this end one had to make an effort to optimize the scalar speed and, most importantly, get a speed-up of approximately a factor of 5 using OpenMP.

  11. Transcribed Media | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Home Transcribed Media SC Home About ASCR HEP SBIR & STTR WDTS Contact Information Office of Science U.S. Department of Energy 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5430 Print Text Size: A A A FeedbackShare Page SC Home 2012 2013 Ernest Orlando Lawrence Award Ceremony 2014 Ernest Orlando Lawrence Award Ceremony 2016 PECASE Award Ceremony A Flight Through the Universe, by the Sloan Digital Sky Survey Behind the Scenes at Berkeley Lab Science Lecture Series: Dr. Goyal

  12. DOE - Office of Legacy Management -- General Motors Co - Flint - MI 07

    Office of Legacy Management (LM)

    Motors Co - Flint - MI 07 FUSRAP Considered Sites Site: GENERAL MOTORS CO. (MI.07 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: A.C. Spark Plug Dort Highway Plant MI.07-1 MI.07-2 Location: Flint , Michigan MI.07-1 Evaluation Year: 1987 MI.07-3 Site Operations: Processed thorium oxide, uranium oxide, and beryllium oxide into crucibles for the Chicago Area. MI.07-3 MI.07-4 MI.07-5 Site Disposition: Eliminated - Potential for contamination

  13. MINOS Experiment and NuMI Beam Home Page

    Broader source: All U.S. Department of Energy (DOE) Office Webpages

    NuMI-MINOS Neutrino Logo NuMI Beamline and MINOS Experiment Neutrino Logo The MINOS Experiment and NuMI Beamline Fermilab Logo MINOS Experiment Links ◊ MINOS for the Public ◊ Scientific Results ◊ MINOS at Work ◊ NuMI at Work ◊ MINOS+ Experiment Fermilab Neutrino Links ◊ Neutrino FAQ ◊ MINOS Underground Areas at Fermilab ◊ PPD Intensity Frontier Dept Back to - - - ◊ Fermilab at Work ◊ Fermilab Home the MINOS Far Detector in the Soudan Mine MINOS collaborators assembling the

  14. Magnetocrystalline anisotropy in <mi>UMn>2<mi>Ge>2 and related Mn-based actinide ferromagnets

    SciTech Connect (OSTI)

    Parker, David S.; Ghimire, Nirmal; Singleton, John; Thompson, J. D.; Bauer, Eric D.; Baumbach, Ryan; Mandrus, David; Li, Ling; Singh, David J.

    2015-05-04

    We present magnetization isotherms in pulsed magnetic fields up to 62 Tesla, supported by first principles calculations, demonstrating a huge uniaxial magnetocrystalline anisotropy energy - approximately 20 MJ/m3 - in <mi>UMn>2<mi>Ge>2. This large anisotropy results from the extremely strong spin-orbit coupling affecting the uranium 5 f electrons, which in the calculations exhibit a substantial orbital moment exceeding 2 μB. Finally, we also find from theoretical calculations that a number of isostructural Mn-actinide compounds are expected to have similarly large anisotropy.

  15. ,"Detroit, MI Natural Gas Pipeline Imports From Canada (MMcf...

    U.S. Energy Information Administration (EIA) Indexed Site

    ,"Worksheet Name","Description"," Of Series","Frequency","Latest Data for" ,"Data 1","Detroit, MI Natural Gas Pipeline Imports From Canada (MMcf)",1,"Annual",2014 ,"Release...

  16. Facilities | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Facilities Advanced Scientific Computing Research (ASCR) ASCR Home About Research Facilities User Facilities Accessing ASCR Facilities Computational Science Graduate Fellowship (CSGF) Research & Evaluation Prototypes (REP) Science Highlights Benefits of ASCR Funding Opportunities Advanced Scientific Computing Advisory Committee (ASCAC) Community Resources Contact Information Advanced Scientific Computing Research U.S. Department of Energy SC-21/Germantown Building 1000 Independence Ave., SW

  17. Featured Content | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Resources » Featured Content Advanced Scientific Computing Research (ASCR) ASCR Home About Research Facilities Science Highlights Benefits of ASCR Funding Opportunities Advanced Scientific Computing Advisory Committee (ASCAC) Community Resources Featured Content 2016 Archive ASCR Discovery ASCR Program Documents ASCR Workshops and Conferences Contact Information Advanced Scientific Computing Research U.S. Department of Energy SC-21/Germantown Building 1000 Independence Ave., SW Washington, DC

  18. Ethical Principles | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Ethical Principles Human Subjects Protection Program (HSPP) HSPP Home About Institutional Review Boards (IRBs) Education and Resources Regulations and Requirements Ethical Principles Federal Regulations DOE Special Requirements Health Insurance Portability and Accountability Act (HIPAA) Glossary Abbreviations Contact BER Home Contact Information Human Subjects Protection Program U.S. Department of Energy SC-23/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 Regulations and

  19. Federal Regulations | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Federal Regulations Human Subjects Protection Program (HSPP) HSPP Home About Institutional Review Boards (IRBs) Education and Resources Regulations and Requirements Ethical Principles Federal Regulations DOE Special Requirements Health Insurance Portability and Accountability Act (HIPAA) Glossary Abbreviations Contact BER Home Contact Information Human Subjects Protection Program U.S. Department of Energy SC-23/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 Regulations and

  20. Funding Opportunities | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Opportunities Fusion Energy Sciences (FES) FES Home About Research Facilities Science Highlights Benefits of FES Funding Opportunities Closed Funding Opportunity Announcements (FOAs) Closed Lab Announcements Award Search / Public Abstracts Additional Requirements and Guidance for Digital Data Management Fusion Energy Sciences Advisory Committee (FESAC) Community Resources Contact Information Fusion Energy Sciences U.S. Department of Energy SC-24/Germantown Building 1000 Independence Ave., SW

  1. V, Ii. Pat-SC&~, Ciructor, Elvision of Techdcal Jkitiseru

    Office of Legacy Management (LM)

    V, Ii. Pat-SC&, Ciructor, Elvision of Techdcal Jkitiseru I?. J. %.Ltl2, Jr., chief, 5isC81bleDU3 Cperstions jw;ta, Prodcc' s.on Giviaion S-A-fiCi : PC: 3JS:?dl please '& advised...

  2. Final Technical Report to DOE for the Award DE-SC0004601 (Technical...

    Office of Scientific and Technical Information (OSTI)

    Technical Report: Final Technical Report to DOE for the Award DE-SC0004601 Citation Details In-Document Search Title: Final Technical Report to DOE for the Award DE-SC0004601 ...

  3. EA-387 Energia Renovable S.C., LLC | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    7 Energia Renovable S.C., LLC EA-387 Energia Renovable S.C., LLC Order authorizing Energia Renovable to export electric energy to Mexico. PDF icon EA-387 Energia Renovable (MX).pdf ...

  4. Distribution List: For Action: Joseph A. McBrearty, SC-3 John...

    Broader source: Energy.gov (indexed) [DOE]

    SC-OR Patricia Schuneman, SC-CH Jeffrey C. Armstrong, SR David Hess, EMCBC Diane Snow, CBFO Michael Adams, NE-ID Kelly Gele, FE-4451 Department of Energy M&O CONTRACTOR...

  5. Manage Your Grant | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Standard reporting requirements for DOE's Office of Science (SC) are set forth on SC's Grants and Contracts web site here. Specific guidance for EPSCoR grantees is provided below. ...

  6. About | U.S. DOE Office of Science (SC)

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    About Integrated Support Center (ISC) ISC Home About Jobs Services Freedom of Information Act (FOIA) Privacy Act NEPA Documents Contact Information Integrated Support Center Roxanne Purucker U.S. Department of Energy 9800 S. Cass Avenue Argonne, IL 60439 P: (630) 252-2110 Kenneth Tarcza U.S. Department of Energy 200 Administration Road Oak Ridge, TN 37830 P: (865) 576-4444 About Print Text Size: A A A FeedbackShare Page Mission We provide specialized professional services essential to the

  7. Jobs | U.S. DOE Office of Science (SC)

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    About » Jobs Integrated Support Center (ISC) ISC Home About Jobs Services Freedom of Information Act (FOIA) Privacy Act NEPA Documents Contact Information Integrated Support Center Roxanne Purucker U.S. Department of Energy 9800 S. Cass Avenue Argonne, IL 60439 P: (630) 252-2110 Kenneth Tarcza U.S. Department of Energy 200 Administration Road Oak Ridge, TN 37830 P: (865) 576-4444 About Jobs Print Text Size: A A A Subscribe FeedbackShare Page Current Open Federal Positions The ISC is a virtual

  8. Jobs | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    About » Jobs Oak Ridge National Laboratory Site Office (OSO) OSO Home About Organization Chart .pdf file (317KB) Jobs Projects Contract Management NEPA Documents Contact Information Oak Ridge National Laboratory Site Office U.S. Department of Energy Post Office Box 2008 Oak Ridge, TN 37831-6269 P: (865) 576-0710 About Jobs Print Text Size: A A A Subscribe FeedbackShare Page Current Open Federal Positions The Oak Ridge National Laboratory Site Office is located in Oak Ridge, Tennessee. All open

  9. Identification of multiple mercury sources to stream sediments near Oak Ridge, TN, USA

    SciTech Connect (OSTI)

    Donovan, Patrick M.; Blum, Joel D.; Demers, Jason D.; Gu, Baohua; Brooks, Scott C.; Peryam, John

    2014-03-03

    In this paper, sediments were analyzed for total Hg concentration (THg) and isotopic composition from streams and rivers in the vicinity of the Y-12 National Security Complex (Y12) in Oak Ridge, TN (USA). In the stream directly draining Y12, where industrial releases of mercury (Hg) have been documented, high THg (3.26 to 60.1 μg/g) sediments had a distinct Hg isotopic composition (δ202Hg of 0.02 ± 0.15‰ and Δ199Hg of -0.07 ± 0.03‰; mean ± 1SD, n=12) compared to sediments from relatively uncontaminated streams in the region (δ202Hg = -1.40 ± 0.06‰ and Δ199Hg of –0.26 ± 0.03‰; mean ± 1SD, n=6). Additionally, several streams that are nearby but do not drain Y12 had sediments with intermediate THg (0.06 to 0.21 μg/g) and anomalous δ202Hg (as low as -5.07‰). We suggest that the low δ202Hg values in these sediments provide evidence for the contribution of an additional Hg source to sediments, possibly derived from atmospheric deposition. In sediments directly downstream of Y12 this third Hg source is not discernible and the Hg isotopic composition can be largely explained by the mixing of low THg sediments with high THg sediments contaminated by Y12 discharges.

  10. Identification of multiple mercury sources to stream sediments near Oak Ridge, TN, USA

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Donovan, Patrick M.; Blum, Joel D.; Demers, Jason D.; Gu, Baohua; Brooks, Scott C.; Peryam, John

    2014-03-03

    In this paper, sediments were analyzed for total Hg concentration (THg) and isotopic composition from streams and rivers in the vicinity of the Y-12 National Security Complex (Y12) in Oak Ridge, TN (USA). In the stream directly draining Y12, where industrial releases of mercury (Hg) have been documented, high THg (3.26 to 60.1 μg/g) sediments had a distinct Hg isotopic composition (δ202Hg of 0.02 ± 0.15‰ and Δ199Hg of -0.07 ± 0.03‰; mean ± 1SD, n=12) compared to sediments from relatively uncontaminated streams in the region (δ202Hg = -1.40 ± 0.06‰ and Δ199Hg of –0.26 ± 0.03‰; mean ± 1SD,more » n=6). Additionally, several streams that are nearby but do not drain Y12 had sediments with intermediate THg (0.06 to 0.21 μg/g) and anomalous δ202Hg (as low as -5.07‰). We suggest that the low δ202Hg values in these sediments provide evidence for the contribution of an additional Hg source to sediments, possibly derived from atmospheric deposition. In sediments directly downstream of Y12 this third Hg source is not discernible and the Hg isotopic composition can be largely explained by the mixing of low THg sediments with high THg sediments contaminated by Y12 discharges.« less

  11. F-1 U.S. Energy Information Administration | Annual Energy Outlook...

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    Central West North Central East North Central Mountain AK WA MT WY ID NV UT CO AZ NM TX OK IA KS MO IL IN KY TN MS AL FL GA SC NC WV PA NJ MD DE NY CT VT ME RI MA NH VA WI MI OH...

  12. F-5 U.S. Energy Information Administration | Annual Energy Outlook...

    Annual Energy Outlook [U.S. Energy Information Administration (EIA)]

    Figure F4. Oil and Gas Supply Model Regions Atlantic WA MT WY ID NV UT CO AZ NM TX OK IA KS MO IL IN KY TN MS AL FL GA SC NC WV PA NJ MD DE NY CT ME RI MA NH VA WI MI OH NE...

  13. Chapter V

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... AL LA GA AR NC NY MI PA IN VA MS TN KY OH ME SC WV MD VT MA NH CT NJ DE R I DC b Coal Fired Power Plant Supplied by the Powder River Basin Powder River Basin 0 220 110 Miles The ...

  14. Review Dates (updated August 2016) | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Review Dates (updated August 2016) Project Assessment (OPA) OPA Home About Project Management SC Projects Review Dates (updated August 2016) Project Construction Photos Other Links SC Federal Project Directors (FPD) and FPD Resources Contact Information Project Assessment U.S. Department of Energy SC-28/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-4840 F: (301) 903-8520 E: Email Us SC Projects Review Dates (updated August 2016) Print Text Size: A A A

  15. Project Construction Photos | U.S. DOE Office of Science (SC)

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    Project Construction Photos Project Assessment (OPA) OPA Home About Project Management SC Projects Review Dates (updated August 2016) Project Construction Photos Completed Projects Current Projects Other Links SC Federal Project Directors (FPD) and FPD Resources Contact Information Project Assessment U.S. Department of Energy SC-28/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-4840 F: (301) 903-8520 E: Email Us SC Projects Project Construction Photos Print Text

  16. Role for DNA methylation in the regulation of miR-200c and miR-141 expression in normal and cancer cells

    SciTech Connect (OSTI)

    Vrba, Lukas; Jensen, Taylor J.; Garbe, James C.; Heimark, Ronald L.; Cress, Anne E.; Dickinson, Sally; Stampfer, Martha R.; Futscher, Bernard W.

    2009-12-23

    BACKGROUND: The microRNA-200 family participates in the maintenance of an epithelial phenotype and loss of its expression can result in epithelial to mesenchymal transition (EMT). Furthermore, the loss of expression of miR-200 family members is linked to an aggressive cancer phenotype. Regulation of the miR-200 family expression in normal and cancer cells is not fully understood. METHODOLOGY/ PRINCIPAL FINDINGS: Epigenetic mechanisms participate in the control of miR-200c and miR-141 expression in both normal and cancer cells. A CpG island near the predicted mir-200c/mir-141 transcription start site shows a striking correlation between miR-200c and miR-141 expression and DNA methylation in both normal and cancer cells, as determined by MassARRAY technology. The CpG island is unmethylated in human miR-200/miR-141 expressing epithelial cells and in miR-200c/miR-141 positive tumor cells. The CpG island is heavily methylated in human miR-200c/miR-141 negative fibroblasts and miR-200c/miR-141 negative tumor cells. Mouse cells show a similar inverse correlation between DNA methylation and miR-200c expression. Enrichment of permissive histone modifications, H3 acetylation and H3K4 trimethylation, is seen in normal miR-200c/miR-141-positive epithelial cells, as determined by chromatin immunoprecipitation coupled to real-time PCR. In contrast, repressive H3K9 dimethylation marks are present in normal miR-200c/miR-141-negative fibroblasts and miR-200c/miR-141 negative cancer cells and the permissive histone modifications are absent. The epigenetic modifier drug, 5-aza-2'-deoxycytidine, reactivates miR-200c/miR-141 expression showing that epigenetic mechanisms play a functional role in their transcriptional control. CONCLUSIONS/ SIGNIFICANCE: We report that DNA methylation plays a role in the normal cell type-specific expression of miR-200c and miR-141 and this role appears evolutionarily conserved, since similar results were obtained in mouse. Aberrant DNA methylation of the

  17. miR-92a family and their target genes in tumorigenesis and metastasis

    SciTech Connect (OSTI)

    Li, Molin; Guan, Xingfang; Sun, Yuqiang; Mi, Jun; Shu, Xiaohong; Liu, Fang; Li, Chuangang

    2014-04-15

    The miR-92a family, including miR-25, miR-92a-1, miR-92a-2 and miR-363, arises from three different paralog clusters miR-17-92, miR-106a-363, and miR-106b-25 that are highly conservative in the process of evolution, and it was thought as a group of microRNAs (miRNAs) correlated with endothelial cells. Aberrant expression of miR-92a family was detected in multiple cancers, and the disturbance of miR-92a family was related with tumorigenesis and tumor development. In this review, the progress on the relationship between miR-92a family and their target genes and malignant tumors will be summarized. - Highlights: Aberrant expression of miR-92a, miR-25 and miR-363 can be observed in many kinds of malignant tumors. The expression of miR-92a family is regulated by LOH, epigenetic alteration, transcriptional factors such as SP1, MYC, E2F, wild-type p53 etc. Roles of miR-92a family in tumorigenesis and development: promoting cell proliferation, invasion and metastasis, inhibiting cell apoptosis.

  18. Science Highlights | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Science Highlights Energy Frontier Research Centers (EFRCs) EFRCs Home Centers Research Science Highlights Highlight Archives News & Events Publications History Contact BES Home Science Highlights Print Text Size: A A A Subscribe FeedbackShare Page Filter by Performer Or press Esc Key to close. close Select all that apply. University DOE Laboratory Industry SC User Facilities ASCR User Facilities [+] Options « ASCR User Facilities National Energy Research Scientific Computing Center (NERSC)

  19. Science Highlights | U.S. DOE Office of Science (SC)

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    Science Highlights Materials Sciences and Engineering (MSE) Division MSE Home About Research Areas Reports and Activities Science Highlights Highlight Archives Principal Investigators' Meetings BES Home Science Highlights Print Text Size: A A A FeedbackShare Page Filter by Performer Or press Esc Key to close. close Select all that apply. University DOE Laboratory Industry SC User Facilities ASCR User Facilities [+] Options « ASCR User Facilities National Energy Research Scientific Computing

  20. NP Budget | U.S. DOE Office of Science (SC)

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    Budget Nuclear Physics (NP) NP Home About Organization Chart .pdf file (90KB) Staff NP Budget NP Committees of Visitors Directions Jobs Labs & Universities Nuclear Physics Related Brochures Research Facilities Science Highlights Benefits of NP Funding Opportunities Nuclear Science Advisory Committee (NSAC) Community Resources Contact Information Nuclear Physics U.S. Department of Energy SC-26/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3613 F: (301)

  1. NREL: Photovoltaics Research - Greg Wilson, D.Sc.

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    Greg Wilson, D.Sc. Director, Materials Applications & Performance Center Co-Director, National Center for Photovoltaics Photo of Greg Wilson 303-384-7950 gregory.wilson@nrel.gov Dr. Greg Wilson is the Director of the Materials Applications and Performance Center and the Co-Director of the National Center for Photovoltaics (NCPV) at the National Renewable Energy Laboratory. He is responsible for NREL's capabilities in high-efficiency crystalline PV, PV cell and module performance, and PV

  2. Energy Frontier | U.S. DOE Office of Science (SC)

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    Energy Frontier High Energy Physics (HEP) HEP Home About Research Science Drivers of Particle Physics Energy Frontier Experiments Intensity Frontier Cosmic Frontier Theoretical and Computational Physics Advanced Technology R&D Accelerator Stewardship Facilities Science Highlights Benefits of HEP Funding Opportunities Advisory Committees Community Resources Contact Information High Energy Physics U.S. Department of Energy SC-25/Germantown Building 1000 Independence Ave., SW Washington, DC

  3. Facilities | U.S. DOE Office of Science (SC)

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    Facilities Biological and Environmental Research (BER) BER Home About Research Facilities User Facilities Science Highlights Benefits of BER Funding Opportunities Biological & Environmental Research Advisory Committee (BERAC) Community Resources Contact Information Biological and Environmental Research U.S. Department of Energy SC-23/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3251 F: (301) 903-5051 E: Email Us More Information » Facilities Print Text

  4. Facilities | U.S. DOE Office of Science (SC)

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    Facilities Fusion Energy Sciences (FES) FES Home About Research Facilities User Facilities ITER External link Science Highlights Benefits of FES Funding Opportunities Fusion Energy Sciences Advisory Committee (FESAC) Community Resources Contact Information Fusion Energy Sciences U.S. Department of Energy SC-24/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-4941 F: (301) 903-8584 E: Email Us More Information » Facilities Print Text Size: A A A FeedbackShare Page

  5. Facilities | U.S. DOE Office of Science (SC)

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    Facilities High Energy Physics (HEP) HEP Home About Research Facilities User Facilities Facility Ops Projects, Missions, and Status Science Highlights Benefits of HEP Funding Opportunities Advisory Committees Community Resources Contact Information High Energy Physics U.S. Department of Energy SC-25/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3624 F: (301) 903-2597 E: Email Us More Information » Facilities Print Text Size: A A A FeedbackShare Page The

  6. Facilities | U.S. DOE Office of Science (SC)

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    Facilities Nuclear Physics (NP) NP Home About Research Facilities User Facilities Project Development Isotope Program Facilities Science Highlights Benefits of NP Funding Opportunities Nuclear Science Advisory Committee (NSAC) Community Resources Contact Information Nuclear Physics U.S. Department of Energy SC-26/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3613 F: (301) 903-3833 E: Email Us More Information » Facilities Print Text Size: A A A FeedbackShare

  7. Featured Content | U.S. DOE Office of Science (SC)

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    Resources » Featured Content Fusion Energy Sciences (FES) FES Home About Research Facilities Science Highlights Benefits of FES Funding Opportunities Fusion Energy Sciences Advisory Committee (FESAC) Community Resources Featured Content 2016 Workshop Reports FES Presentations FES Program Documents Contact Information Fusion Energy Sciences U.S. Department of Energy SC-24/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-4941 F: (301) 903-8584 E: Email Us More

  8. Featured Content | U.S. DOE Office of Science (SC)

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    Content High Energy Physics (HEP) HEP Home About Research Facilities Science Highlights Benefits of HEP Funding Opportunities Advisory Committees Community Resources Featured Content 2016 2015 2014 2013 2012-2008 Reports Contact Information High Energy Physics U.S. Department of Energy SC-25/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3624 F: (301) 903-2597 E: Email Us More Information » Community Resources Featured Content Print Text Size: A A A

  9. Robin Hayes | U.S. DOE Office of Science (SC)

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    Robin Hayes Basic Energy Sciences (BES) BES Home About Organization Chart .pdf file (132KB) Staff BES Budget BES Committees of Visitors Directions Jobs Organizational History Research Facilities Science Highlights Benefits of BES Funding Opportunities Basic Energy Sciences Advisory Committee (BESAC) Community Resources Contact Information Basic Energy Sciences U.S. Department of Energy SC-22/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3081 F: (301) 903-6594

  10. About | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    2016 Advanced Scientific Computing Research (ASCR) ASCR Home About Research Facilities Science Highlights Benefits of ASCR Funding Opportunities Advanced Scientific Computing Advisory Committee (ASCAC) Community Resources Featured Content 2016 Archive ASCR Discovery ASCR Program Documents ASCR Workshops and Conferences Contact Information Advanced Scientific Computing Research U.S. Department of Energy SC-21/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-7486 F:

  11. Regional Competitions | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Program Contacts Laboratory Policy (LP) LP Home About Laboratory Appraisal Process Laboratory Planning Process Laboratory Directed Research and Development (LDRD) Frequently Asked Questions Impact Legislative History Program Contacts Management & Operating (M&O) Contracts Technology Transfer Strategic Partnership Projects (SPP) Contact Information Laboratory Policy U.S. Department of Energy SC-32/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5447 F:

  12. 2012 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    2 Advanced Scientific Computing Research (ASCR) ASCR Home About Research Facilities Science Highlights Benefits of ASCR Funding Opportunities Advanced Scientific Computing Advisory Committee (ASCAC) Community Resources Contact Information Advanced Scientific Computing Research U.S. Department of Energy SC-21/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-7486 F: (301) 903-4846 E: Email Us More Information » Science Highlights 2012 Print Text Size: A A A

  13. 2012 | U.S. DOE Office of Science (SC)

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    2 Fusion Energy Sciences (FES) FES Home About Research Facilities Science Highlights Benefits of FES Funding Opportunities Fusion Energy Sciences Advisory Committee (FESAC) Community Resources Contact Information Fusion Energy Sciences U.S. Department of Energy SC-24/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-4941 F: (301) 903-8584 E: Email Us More Information » Science Highlights 2012 Print Text Size: A A A FeedbackShare Page Filter by Performer Or press

  14. 2013 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    3 Advanced Scientific Computing Research (ASCR) ASCR Home About Research Facilities Science Highlights Benefits of ASCR Funding Opportunities Advanced Scientific Computing Advisory Committee (ASCAC) Community Resources Contact Information Advanced Scientific Computing Research U.S. Department of Energy SC-21/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-7486 F: (301) 903-4846 E: Email Us More Information » Science Highlights 2013 Print Text Size: A A A

  15. 2013 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    3 Basic Energy Sciences (BES) BES Home About Research Facilities Science Highlights Benefits of BES Funding Opportunities Basic Energy Sciences Advisory Committee (BESAC) Community Resources Contact Information Basic Energy Sciences U.S. Department of Energy SC-22/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3081 F: (301) 903-6594 E: Email Us More Information » Science Highlights 2013 Print Text Size: A A A FeedbackShare Page Filter by Performer Or press Esc

  16. 2013 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    3 Nuclear Physics (NP) NP Home About Research Facilities Science Highlights Benefits of NP Funding Opportunities Nuclear Science Advisory Committee (NSAC) Community Resources Contact Information Nuclear Physics U.S. Department of Energy SC-26/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3613 F: (301) 903-3833 E: Email Us More Information » Science Highlights 2013 Print Text Size: A A A FeedbackShare Page Filter by Performer Or press Esc Key to close. close

  17. 2013 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    3 Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) SBIR/STTR Home About Funding Opportunity Announcements (FOAs) Applicant and Awardee Resources Commercialization Assistance Other Resources Awards SBIR/STTR Highlights Reporting Fraud Contact Information Small Business Innovation Research and Small Business Technology Transfer U.S. Department of Energy SC-29/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-5707 F: (301)

  18. 2014 | U.S. DOE Office of Science (SC)

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    4 Basic Energy Sciences (BES) BES Home About Research Facilities Science Highlights Benefits of BES Funding Opportunities Basic Energy Sciences Advisory Committee (BESAC) Community Resources Contact Information Basic Energy Sciences U.S. Department of Energy SC-22/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3081 F: (301) 903-6594 E: Email Us More Information » Science Highlights 2014 Print Text Size: A A A FeedbackShare Page Filter by Performer Or press Esc

  19. 2014 | U.S. DOE Office of Science (SC)

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    4 Nuclear Physics (NP) NP Home About Research Facilities Science Highlights Benefits of NP Funding Opportunities Nuclear Science Advisory Committee (NSAC) Community Resources Contact Information Nuclear Physics U.S. Department of Energy SC-26/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3613 F: (301) 903-3833 E: Email Us More Information » Science Highlights 2014 Print Text Size: A A A FeedbackShare Page Filter by Performer Or press Esc Key to close. close

  20. 2014 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    4 Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) SBIR/STTR Home About Funding Opportunity Announcements (FOAs) Applicant and Awardee Resources Commercialization Assistance Other Resources Awards SBIR/STTR Highlights Reporting Fraud Contact Information Small Business Innovation Research and Small Business Technology Transfer U.S. Department of Energy SC-29/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-5707 F: (301)

  1. 2015 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    5 Advanced Scientific Computing Research (ASCR) ASCR Home About Research Facilities Science Highlights Benefits of ASCR Funding Opportunities Advanced Scientific Computing Advisory Committee (ASCAC) Community Resources Contact Information Advanced Scientific Computing Research U.S. Department of Energy SC-21/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-7486 F: (301) 903-4846 E: Email Us More Information » Science Highlights 2015 Print Text Size: A A A

  2. 2015 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    5 Basic Energy Sciences (BES) BES Home About Research Facilities Science Highlights Benefits of BES Funding Opportunities Basic Energy Sciences Advisory Committee (BESAC) Community Resources Contact Information Basic Energy Sciences U.S. Department of Energy SC-22/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3081 F: (301) 903-6594 E: Email Us More Information » Science Highlights 2015 Print Text Size: A A A FeedbackShare Page Filter by Performer Or press Esc

  3. 2015 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    5 Fusion Energy Sciences (FES) FES Home About Research Facilities Science Highlights Benefits of FES Funding Opportunities Fusion Energy Sciences Advisory Committee (FESAC) Community Resources Contact Information Fusion Energy Sciences U.S. Department of Energy SC-24/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-4941 F: (301) 903-8584 E: Email Us More Information » Science Highlights 2015 Print Text Size: A A A FeedbackShare Page Filter by Performer Or press

  4. 2015 | U.S. DOE Office of Science (SC)

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    5 Nuclear Physics (NP) NP Home About Research Facilities Science Highlights Benefits of NP Funding Opportunities Nuclear Science Advisory Committee (NSAC) Community Resources Contact Information Nuclear Physics U.S. Department of Energy SC-26/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3613 F: (301) 903-3833 E: Email Us More Information » Science Highlights 2015 Print Text Size: A A A FeedbackShare Page Filter by Performer Or press Esc Key to close. close

  5. 2015 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    5 Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) SBIR/STTR Home About Funding Opportunity Announcements (FOAs) Applicant and Awardee Resources Commercialization Assistance Other Resources Awards SBIR/STTR Highlights Reporting Fraud Contact Information Small Business Innovation Research and Small Business Technology Transfer U.S. Department of Energy SC-29/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-5707 F: (301)

  6. 2016 | U.S. DOE Office of Science (SC)

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    6 Fusion Energy Sciences (FES) FES Home About Research Facilities Science Highlights Benefits of FES Funding Opportunities Fusion Energy Sciences Advisory Committee (FESAC) Community Resources Contact Information Fusion Energy Sciences U.S. Department of Energy SC-24/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-4941 F: (301) 903-8584 E: Email Us More Information » Science Highlights 2016 Print Text Size: A A A FeedbackShare Page Filter by Performer Or press

  7. Ames Laboratory | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Ames Laboratory Laboratory Policy (LP) LP Home About Laboratory Appraisal Process FY 2015 Report Cards FY 2014 Report Cards FY 2013 Report Cards Report Card Archives Laboratory Planning Process Laboratory Directed Research and Development (LDRD) Management & Operating (M&O) Contracts Technology Transfer Strategic Partnership Projects (SPP) Contact Information Laboratory Policy U.S. Department of Energy SC-32/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202)

  8. Ames Laboratory | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Ames Laboratory Laboratory Policy (LP) LP Home About Laboratory Appraisal Process FY 2015 Report Cards FY 2014 Report Cards FY 2013 Report Cards Report Card Archives Laboratory Planning Process Laboratory Directed Research and Development (LDRD) Management & Operating (M&O) Contracts Technology Transfer Strategic Partnership Projects (SPP) Contact Information Laboratory Policy U.S. Department of Energy SC-32/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202)

  9. Ames Laboratory | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Ames Laboratory Laboratory Policy (LP) LP Home About Laboratory Appraisal Process FY 2015 Report Cards FY 2014 Report Cards FY 2013 Report Cards Report Card Archives Laboratory Planning Process Laboratory Directed Research and Development (LDRD) Management & Operating (M&O) Contracts Technology Transfer Strategic Partnership Projects (SPP) Contact Information Laboratory Policy U.S. Department of Energy SC-32/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202)

  10. Archives | U.S. DOE Office of Science (SC)

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    Archives Basic Energy Sciences (BES) BES Home About Research Facilities Science Highlights Benefits of BES Funding Opportunities Basic Energy Sciences Advisory Committee (BESAC) Community Resources Program Summaries Brochures Reports Accomplishments Discoveries Nobel Prizes Vignettes Archives Presentations BES and Congress Science for Energy Flow Seeing Matter Nano for Energy Scale of Things Chart Contact Information Basic Energy Sciences U.S. Department of Energy SC-22/Germantown Building 1000

  11. DOE Resources | U.S. DOE Office of Science (SC)

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    DOE Resources Human Subjects Protection Program (HSPP) HSPP Home About Institutional Review Boards (IRBs) Education and Resources CITI Courses DOE Resources Ethical Framework Informed Consent Special Research Categories Community IRB Member Resources Other Resources Human Subjects Research Database (HSRD) IRB7 Regulations and Requirements Glossary Abbreviations Contact BER Home Contact Information Human Subjects Protection Program U.S. Department of Energy SC-23/Germantown Building 1000

  12. Discoveries | U.S. DOE Office of Science (SC)

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  13. European Labs | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    European Labs Nuclear Physics (NP) NP Home About Research Facilities Science Highlights Benefits of NP Applications of Nuclear Science Small Business Innovation Research / Small Business Technology Transfer Funding Opportunities Nuclear Science Advisory Committee (NSAC) Community Resources Contact Information Nuclear Physics U.S. Department of Energy SC-26/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3613 F: (301) 903-3833 E: Email Us More Information »

  14. Informed Consent | U.S. DOE Office of Science (SC)

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    Informed Consent Human Subjects Protection Program (HSPP) HSPP Home About Institutional Review Boards (IRBs) Education and Resources CITI Courses DOE Resources Informed Consent Special Research Categories Community IRB Member Resources Other Resources Human Subjects Research Database (HSRD) IRB7 Regulations and Requirements Glossary Abbreviations Contact BER Home Contact Information Human Subjects Protection Program U.S. Department of Energy SC-23/Germantown Building 1000 Independence Ave., SW

  15. Leads | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Leads Human Subjects Protection Program (HSPP) HSPP Home About For Researchers For IRB Managers / Administrators For IRB Members For Institutional Officials For Prospective Human Subjects Leads Annual Reports Institutional Review Boards (IRBs) Education and Resources Regulations and Requirements Glossary Abbreviations Contact BER Home Contact Information Human Subjects Protection Program U.S. Department of Energy SC-23/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 About

  16. Local Map | U.S. DOE Office of Science (SC)

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    About » Directions » Local Map Nuclear Physics (NP) NP Home About Organization Chart .pdf file (89KB) Staff NP Budget NP Committees of Visitors Directions Local Map Jobs Labs & Universities Nuclear Physics Related Brochures Research Facilities Science Highlights Benefits of NP Funding Opportunities Nuclear Science Advisory Committee (NSAC) Community Resources Contact Information Nuclear Physics U.S. Department of Energy SC-26/Germantown Building 1000 Independence Ave., SW Washington, DC

  17. Nidc Orgchart | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Nidc Orgchart Nuclear Physics (NP) NP Home About Research Facilities Science Highlights Benefits of NP Funding Opportunities Nuclear Science Advisory Committee (NSAC) Community Resources Contact Information Nuclear Physics U.S. Department of Energy SC-26/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3613 F: (301) 903-3833 E: Email Us More Information » Isotope Development & Production for Research and Applications (IDPRA) Nidc Orgchart Print Text Size: A A

  18. Nobel Prizes | U.S. DOE Office of Science (SC)

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    Nobel Prizes Basic Energy Sciences (BES) BES Home About Research Facilities Science Highlights Benefits of BES Funding Opportunities Basic Energy Sciences Advisory Committee (BESAC) Community Resources Program Summaries Brochures Reports Accomplishments Discoveries Nobel Prizes Vignettes Archives Presentations BES and Congress Science for Energy Flow Seeing Matter Nano for Energy Scale of Things Chart Contact Information Basic Energy Sciences U.S. Department of Energy SC-22/Germantown Building

  19. Origins | U.S. DOE Office of Science (SC)

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    Origins Fusion Energy Sciences (FES) FES Home About Research Fusion Institutions Fusion Links International Activities Facilities Science Highlights Benefits of FES Funding Opportunities Fusion Energy Sciences Advisory Committee (FESAC) Community Resources Contact Information Fusion Energy Sciences U.S. Department of Energy SC-24/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-4941 F: (301) 903-8584 E: Email Us More Information » International Activities Origins

  20. Other Resources | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Other Resources Human Subjects Protection Program (HSPP) HSPP Home About Institutional Review Boards (IRBs) Education and Resources CITI Courses DOE Resources Informed Consent Special Research Categories Community IRB Member Resources Other Resources Human Subjects Research Database (HSRD) IRB7 Regulations and Requirements Glossary Abbreviations Contact BER Home Contact Information Human Subjects Protection Program U.S. Department of Energy SC-23/Germantown Building 1000 Independence Ave., SW

  1. Posters | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Posters Fusion Energy Sciences (FES) FES Home About Research Fusion Institutions Fusion Links International Activities Facilities Science Highlights Benefits of FES Funding Opportunities Fusion Energy Sciences Advisory Committee (FESAC) Community Resources Contact Information Fusion Energy Sciences U.S. Department of Energy SC-24/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-4941 F: (301) 903-8584 E: Email Us More Information » International Activities Posters

  2. Thiyaga | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Thiyaga P. Thiyagarajan Materials Sciences and Engineering (MSE) Division MSE Home About Staff What's New Research Areas Reports and Activities Science Highlights Principal Investigators' Meetings BES Home Staff Dr. Thiyaga P. Thiyagarajan Print Text Size: A A A FeedbackShare Page Thiyagarajan Program Manager Neutron Scattering Materials Sciences and Engineering Division Office of Basic Energy Sciences SC-22.2/Germantown Building, Rm F-411 U.S. Department of Energy 1000 Independence Avenue, SW

  3. Vignettes | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

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  4. 2011 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    1 Laboratory Policy (LP) LP Home About Laboratory Appraisal Process Laboratory Planning Process Laboratory Directed Research and Development (LDRD) Frequently Asked Questions Impact Legislative History Program Contacts Management & Operating (M&O) Contracts Technology Transfer Strategic Partnership Projects (SPP) Contact Information Laboratory Policy U.S. Department of Energy SC-32/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5447 F: (202) 586-3119 More

  5. 2012 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    2 Laboratory Policy (LP) LP Home About Laboratory Appraisal Process Laboratory Planning Process Laboratory Directed Research and Development (LDRD) Frequently Asked Questions Impact Legislative History Program Contacts Management & Operating (M&O) Contracts Technology Transfer Strategic Partnership Projects (SPP) Contact Information Laboratory Policy U.S. Department of Energy SC-32/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5447 F: (202) 586-3119 More

  6. AEC Headquarters | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    AEC Headquarters Basic Energy Sciences (BES) BES Home About Organization Chart .pdf file (132KB) Staff BES Budget BES Committees of Visitors Directions Jobs Organizational History Germantown Natural History President Kennedy's AEC Briefings Research Facilities Science Highlights Benefits of BES Funding Opportunities Basic Energy Sciences Advisory Committee (BESAC) Community Resources Contact Information Basic Energy Sciences U.S. Department of Energy SC-22/Germantown Building 1000 Independence

  7. Agenda | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    2 Workshop on Isotope Federal Supply and Demand » Agenda Nuclear Physics (NP) NP Home About Research Facilities Science Highlights Benefits of NP Funding Opportunities Nuclear Science Advisory Committee (NSAC) Community Resources NP Workforce Survey Results .pdf file (182KB) Links News Archives Databases Reports Workshops Nuclear Physics Related Brochures and Videos Contact Information Nuclear Physics U.S. Department of Energy SC-26/Germantown Building 1000 Independence Ave., SW Washington, DC

  8. Ames Laboratory | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Ames Laboratory Laboratory Policy (LP) LP Home About Laboratory Appraisal Process FY 2015 Report Cards FY 2014 Report Cards FY 2013 Report Cards Report Card Archives Laboratory Planning Process Laboratory Directed Research and Development (LDRD) Management & Operating (M&O) Contracts Technology Transfer Strategic Partnership Projects (SPP) Contact Information Laboratory Policy U.S. Department of Energy SC-32/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202)

  9. Ames Laboratory | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Ames Laboratory Laboratory Policy (LP) LP Home About Laboratory Appraisal Process FY 2015 Report Cards FY 2014 Report Cards FY 2013 Report Cards Report Card Archives Laboratory Planning Process Laboratory Directed Research and Development (LDRD) Management & Operating (M&O) Contracts Technology Transfer Strategic Partnership Projects (SPP) Contact Information Laboratory Policy U.S. Department of Energy SC-32/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202)

  10. Ames Laboratory | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Ames Laboratory Laboratory Policy (LP) LP Home About Laboratory Appraisal Process FY 2015 Report Cards FY 2014 Report Cards FY 2013 Report Cards Report Card Archives Laboratory Planning Process Laboratory Directed Research and Development (LDRD) Management & Operating (M&O) Contracts Technology Transfer Strategic Partnership Projects (SPP) Contact Information Laboratory Policy U.S. Department of Energy SC-32/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202)

  11. Ames Laboratory | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Ames Laboratory Laboratory Policy (LP) LP Home About Laboratory Appraisal Process FY 2015 Report Cards FY 2014 Report Cards FY 2013 Report Cards Report Card Archives Laboratory Planning Process Laboratory Directed Research and Development (LDRD) Management & Operating (M&O) Contracts Technology Transfer Strategic Partnership Projects (SPP) Contact Information Laboratory Policy U.S. Department of Energy SC-32/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202)

  12. Ames Laboratory | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Ames Laboratory Laboratory Policy (LP) LP Home About Laboratory Appraisal Process FY 2015 Report Cards FY 2014 Report Cards FY 2013 Report Cards Report Card Archives Laboratory Planning Process Laboratory Directed Research and Development (LDRD) Management & Operating (M&O) Contracts Technology Transfer Strategic Partnership Projects (SPP) Contact Information Laboratory Policy U.S. Department of Energy SC-32/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202)

  13. Ames Laboratory | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Ames Laboratory Laboratory Policy (LP) LP Home About Laboratory Appraisal Process FY 2015 Report Cards FY 2014 Report Cards FY 2013 Report Cards Report Card Archives Laboratory Planning Process Laboratory Directed Research and Development (LDRD) Management & Operating (M&O) Contracts Technology Transfer Strategic Partnership Projects (SPP) Contact Information Laboratory Policy U.S. Department of Energy SC-32/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202)

  14. Archives | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Community Resources » Archives Basic Energy Sciences (BES) BES Home About Research Facilities Science Highlights Benefits of BES Funding Opportunities Basic Energy Sciences Advisory Committee (BESAC) Community Resources Program Summaries Brochures Reports Accomplishments Presentations BES and Congress Science for Energy Flow Seeing Matter Nano for Energy Scale of Things Chart Contact Information Basic Energy Sciences U.S. Department of Energy SC-22/Germantown Building 1000 Independence Ave., SW

  15. Bibtexcitationinfo | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    ASCR Home » Community Resources » Miscellaneous » BibTex Citation Info Advanced Scientific Computing Research (ASCR) ASCR Home About Research Facilities Science Highlights Benefits of ASCR Funding Opportunities Advanced Scientific Computing Advisory Committee (ASCAC) Community Resources Featured Content ASCR Discovery ASCR Program Documents ASCR Workshops and Conferences Contact Information Advanced Scientific Computing Research U.S. Department of Energy SC-21/Germantown Building 1000

  16. Coordinator Resources | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Regional Science Bowl Coordinators » Coordinator Resources National Science Bowl® (NSB) NSB Home About Regional Science Bowl Coordinators Alumni Historical Information - National Finals National Science Bowl Logos Regional Competitions National Finals Volunteers Key Dates Frequently Asked Questions News Media Contact Us WDTS Home Contact Information National Science Bowl® U.S. Department of Energy SC-27/ Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 E: Email Us Regional

  17. Full Program | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Agenda / Presentations Nuclear Physics (NP) NP Home About Research Facilities Science Highlights Benefits of NP Funding Opportunities Nuclear Science Advisory Committee (NSAC) Community Resources NP Workforce Survey Results .pdf file (182KB) Links News Archives Databases Reports Workshops Nuclear Physics Related Brochures and Videos Contact Information Nuclear Physics U.S. Department of Energy SC-26/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3613 F: (301)

  18. Fusion Institutions | U.S. DOE Office of Science (SC)

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    Fusion Institutions Fusion Energy Sciences (FES) FES Home About Research Fusion Institutions Fusion Links International Activities Facilities Science Highlights Benefits of FES Funding Opportunities Fusion Energy Sciences Advisory Committee (FESAC) Community Resources Contact Information Fusion Energy Sciences U.S. Department of Energy SC-24/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-4941 F: (301) 903-8584 E: Email Us More Information » Research Fusion

  19. Fusion Links | U.S. DOE Office of Science (SC)

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    Fusion Links Fusion Energy Sciences (FES) FES Home About Research Fusion Institutions Fusion Links International Activities Facilities Science Highlights Benefits of FES Funding Opportunities Fusion Energy Sciences Advisory Committee (FESAC) Community Resources Contact Information Fusion Energy Sciences U.S. Department of Energy SC-24/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-4941 F: (301) 903-8584 E: Email Us More Information » Research Fusion Links Print

  20. DOE SC Exascale Requirements Review: High Energy Physics

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    SC Exascale Requirements Review: High Energy Physics Bethesda Hyatt, June 10, 2015 Jim Siegrist Associate Director for High Energy Physics Office of Science, U.S. Department of Energy HEP Computing and Data Challenges * What's new? * In May 2014, the U.S. particle physics community updated its vision for the future - The P5 (Particle Physics Project Prioritization Panel) report presents a strategy for the next decade and beyond that enables discovery and maintains our position as a global leader

  1. Workshop Reports | U.S. DOE Office of Science (SC)

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    Workshop Reports Fusion Energy Sciences (FES) FES Home About Research Facilities Science Highlights Benefits of FES Funding Opportunities Fusion Energy Sciences Advisory Committee (FESAC) Community Resources Featured Content Workshop Reports FES Presentations FES Program Documents Contact Information Fusion Energy Sciences U.S. Department of Energy SC-24/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-4941 F: (301) 903-8584 E: Email Us More Information »

  2. Medicine | U.S. DOE Office of Science (SC)

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    Medicine High Energy Physics (HEP) HEP Home About Research Facilities Science Highlights Benefits of HEP Medicine Homeland Security Industry Computing Sciences Workforce Development A Growing List Accelerators for Americas Future External link Funding Opportunities Advisory Committees Community Resources Contact Information High Energy Physics U.S. Department of Energy SC-25/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3624 F: (301) 903-2597 E: Email Us More

  3. About | U.S. DOE Office of Science (SC)

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    About Advanced Scientific Computing Research (ASCR) ASCR Home About Organization Chart .pdf file (223KB) Staff ASCR Budget ASCR Committees of Visitors Directions Jobs Research Facilities Science Highlights Benefits of ASCR Funding Opportunities Advanced Scientific Computing Advisory Committee (ASCAC) Community Resources Contact Information Advanced Scientific Computing Research U.S. Department of Energy SC-21/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-7486

  4. About | U.S. DOE Office of Science (SC)

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    About Biological and Environmental Research (BER) BER Home About Organization Chart .pdf file (73KB) Staff BER Budget BER Committees of Visitors Directions Jobs Research Facilities Science Highlights Benefits of BER Funding Opportunities Biological & Environmental Research Advisory Committee (BERAC) Community Resources Contact Information Biological and Environmental Research U.S. Department of Energy SC-23/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3251

  5. About | U.S. DOE Office of Science (SC)

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    About Basic Energy Sciences (BES) BES Home About Organization Chart .pdf file (132KB) Staff BES Budget BES Committees of Visitors Directions Jobs Organizational History Research Facilities Science Highlights Benefits of BES Funding Opportunities Basic Energy Sciences Advisory Committee (BESAC) Community Resources Contact Information Basic Energy Sciences U.S. Department of Energy SC-22/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3081 F: (301) 903-6594 E:

  6. About | U.S. DOE Office of Science (SC)

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    About Fusion Energy Sciences (FES) FES Home About Organization Chart .pdf file (113KB) Staff FES Budget FES Committees of Visitors Directions Jobs Fusion and Plasmas Research Facilities Science Highlights Benefits of FES Funding Opportunities Fusion Energy Sciences Advisory Committee (FESAC) Community Resources Contact Information Fusion Energy Sciences U.S. Department of Energy SC-24/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-4941 F: (301) 903-8584 E: Email

  7. About | U.S. DOE Office of Science (SC)

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    About Grants & Contracts Support Grants & Contracts Support Home About Organization Chart .pdf file (12KB) Jobs Grants/Contracts Differences Federal Agency Proposals Funding Opportunity Announcements (FOAs) DOE National Laboratory Announcements Grants Process Grants Policy and Guidance FAQs Resources Contract Information Contact Information Grants & Contracts Support U.S. Department of Energy SC-43/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 E: Email Us About

  8. About | U.S. DOE Office of Science (SC)

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    Programs » HEP Home » About High Energy Physics (HEP) HEP Home About Organization Chart .pdf file (106KB) Staff HEP Budget HEP Committees of Visitors Directions Jobs University Research & National Labs Research Facilities Science Highlights Benefits of HEP Funding Opportunities Advisory Committees Community Resources Contact Information High Energy Physics U.S. Department of Energy SC-25/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3624 F: (301) 903-2597

  9. About | U.S. DOE Office of Science (SC)

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    About Laboratory Policy (LP) LP Home About Staff Organization Chart .pdf file (103KB) Jobs Laboratory Appraisal Process Laboratory Planning Process Laboratory Directed Research and Development (LDRD) Management & Operating (M&O) Contracts Technology Transfer Strategic Partnership Projects (SPP) Contact Information Laboratory Policy U.S. Department of Energy SC-32/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5447 F: (202) 586-3119 More Information »

  10. About | U.S. DOE Office of Science (SC)

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    About Nuclear Physics (NP) NP Home About Organization Chart .pdf file (90KB) Staff NP Budget NP Committees of Visitors Directions Jobs Labs & Universities Nuclear Physics Related Brochures Research Facilities Science Highlights Benefits of NP Funding Opportunities Nuclear Science Advisory Committee (NSAC) Community Resources Contact Information Nuclear Physics U.S. Department of Energy SC-26/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3613 F: (301)

  11. About | U.S. DOE Office of Science (SC)

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    About Management OM Home About Organization Chart .pdf file (40KB) Director Biography Staff Jobs Program Direction and Analysis Human Resources Advisory Office Administration Contact Information Management U.S. Department of Energy SC-48/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 More Information » About Print Text Size: A A A FeedbackShare Page The Office of Management (OM) serves as the primary corporate resource for administrative management in the Office of Science

  12. About | U.S. DOE Office of Science (SC)

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    About Safety and Security Policy (SSP) SSP Home About Staff Organization Chart .pdf file (103KB) Jobs Frequently Used Resources NEPA Documents Continuity of Operations (COOP) Implementation Plan Contact Information Safety and Security Policy U.S. Department of Energy SC-31/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-6800 F: (301) 903-7047 More Information » About Print Text Size: A A A FeedbackShare Page The Office of Safety and Security Policy proactively

  13. Abstracts | U.S. DOE Office of Science (SC)

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    Reports » Abstracts Basic Energy Sciences (BES) BES Home About Research Facilities Science Highlights Benefits of BES Funding Opportunities Basic Energy Sciences Advisory Committee (BESAC) Community Resources Program Summaries Brochures Reports Abstracts Accomplishments Presentations BES and Congress Science for Energy Flow Seeing Matter Nano for Energy Scale of Things Chart Contact Information Basic Energy Sciences U.S. Department of Energy SC-22/Germantown Building 1000 Independence Ave., SW

  14. Administration | U.S. DOE Office of Science (SC)

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    Administration Management OM Home About Program Direction and Analysis Human Resources Advisory Office Administration Contact Information Management U.S. Department of Energy SC-48/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 More Information » Administration Print Text Size: A A A FeedbackShare Page The Office of Administration provides administrative management programs including logistics requirements, strategic space planning, temporary support services management,

  15. Advisory Committees | U.S. DOE Office of Science (SC)

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    Advisory Committees High Energy Physics (HEP) HEP Home About Research Facilities Science Highlights Benefits of HEP Funding Opportunities Advisory Committees HEPAP AAAC External link Community Resources Contact Information High Energy Physics U.S. Department of Energy SC-25/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3624 F: (301) 903-2597 E: Email Us More Information » Advisory Committees Print Text Size: A A A FeedbackShare Page High Energy Physics

  16. Photoelectrodes Revealed! | U.S. DOE Office of Science (SC)

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    Photoelectrodes Revealed! Basic Energy Sciences (BES) BES Home About Research Facilities Science Highlights Benefits of BES Funding Opportunities Basic Energy Sciences Advisory Committee (BESAC) Community Resources Contact Information Basic Energy Sciences U.S. Department of Energy SC-22/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3081 F: (301) 903-6594 E: Email Us More Information » 08.05.16 Photoelectrodes Revealed! New spectroscopic probe will aid design

  17. Publications | U.S. DOE Office of Science (SC)

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    Publications Communications and Public Affairs Comms Home Research News Publications Contacts Contact Information Communications and Public Affairs U.S. Department of Energy SC-47/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202) 287-5813 E: Email Us More Information » Publications Print Text Size: A A A FeedbackShare Page Office of Science Communications Plan .pdf file (777KB) Office of Science Brochure Office of Science Fact Sheet Universities working with the Office

  18. SC15 High Performance Computing (HPC) Transforms Batteries - Joint Center

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    for Energy Storage Research September 21, 2015, Videos SC15 High Performance Computing (HPC) Transforms Batteries A new breakthrough battery-one that has significantly higher energy, lasts longer, and is cheaper and safer-will likely be impossible without a new material discovery. Kristin Persson and other JCESR scientists at Lawrence Berkeley National Laboratory are taking some of the guesswork out of the discovery process with the Electrolyte Genome Project. Electrolyte Genome

  19. Directions | U.S. DOE Office of Science (SC)

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    Directions Advanced Scientific Computing Research (ASCR) ASCR Home About Organization Chart .pdf file (223KB) Staff ASCR Budget ASCR Committees of Visitors Directions Jobs Research Facilities Science Highlights Benefits of ASCR Funding Opportunities Advanced Scientific Computing Advisory Committee (ASCAC) Community Resources Contact Information Advanced Scientific Computing Research U.S. Department of Energy SC-21/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301)

  20. Directions | U.S. DOE Office of Science (SC)

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    Directions Fusion Energy Sciences (FES) FES Home About Organization Chart .pdf file (113KB) Staff FES Budget FES Committees of Visitors Directions Jobs Fusion and Plasmas Research Facilities Science Highlights Benefits of FES Funding Opportunities Fusion Energy Sciences Advisory Committee (FESAC) Community Resources Contact Information Fusion Energy Sciences U.S. Department of Energy SC-24/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-4941 F: (301) 903-8584 E:

  1. Director Biography | U.S. DOE Office of Science (SC)

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    Director Biography Information Technology and Services (ITS) ITS Home About Organization Chart .pdf file (261KB) Director Biography Jobs Functions Contact Information Information Technology and Services U.S. Department of Energy SC-45/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-0192 F: (301) 903-2481 About Director Biography Print Text Size: A A A FeedbackShare Page Dr. Vasilios Kountouris, Director for Information Technology and Services Dr. Vasilios

  2. Grants Process | U.S. DOE Office of Science (SC)

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    Grants Process Grants & Contracts Support Grants & Contracts Support Home About Funding Opportunity Announcements (FOAs) DOE National Laboratory Announcements Grants Process Grants Policy and Guidance FAQs Resources Contract Information Contact Information Grants & Contracts Support U.S. Department of Energy SC-43/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 E: Email Us Grants Process Print Text Size: A A A FeedbackShare Page Step 1: Registration Obtain a DUNS

  3. User Facilities | U.S. DOE Office of Science (SC)

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    Facilities Fusion Energy Sciences (FES) FES Home About Research Facilities User Facilities DIII-D National Fusion Facility (DIII-D) National Spherical Torus Experiment (NSTX) Alcator C-Mod ITER External link Science Highlights Benefits of FES Funding Opportunities Fusion Energy Sciences Advisory Committee (FESAC) Community Resources Contact Information Fusion Energy Sciences U.S. Department of Energy SC-24/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-4941 F:

  4. Experiments | U.S. DOE Office of Science (SC)

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  5. Experiments | U.S. DOE Office of Science (SC)

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  6. Experiments | U.S. DOE Office of Science (SC)

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  7. FES Budget | U.S. DOE Office of Science (SC)

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    Budget Fusion Energy Sciences (FES) FES Home About Organization Chart .pdf file (113KB) Staff FES Budget FES Committees of Visitors Directions Jobs Fusion and Plasmas Research Facilities Science Highlights Benefits of FES Funding Opportunities Fusion Energy Sciences Advisory Committee (FESAC) Community Resources Contact Information Fusion Energy Sciences U.S. Department of Energy SC-24/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-4941 F: (301) 903-8584 E:

  8. FES Presentations | U.S. DOE Office of Science (SC)

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  9. Intensity Frontier| U.S. DOE Office of Science (SC)

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  10. Improved input and output couplers for SC acceleration structure

    SciTech Connect (OSTI)

    Solyak, N.; Gonin, I.; Latina, A.; Lunin, A.; Poloubotko, V.; Yakovlev, V.; /Fermilab

    2009-04-01

    Different couplers are described that allow the reduction of both transverse wake potential and RF kick in the SC acceleration structure of ILC. A simple rotation of the couplers reducing the RF kick and transverse wake kick is discussed for both the main linac and bunch compressors, along with possible limitations of this method. Designs of a coupler unit are presented which preserve axial symmetry of the structure, and provide reduced both the RF kick and transverse wake field.

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  1. sc0011884-advanced-cooling | netl.doe.gov

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    Innovative, Economical, Ultra-clean Incinerator for Low Heating Value VOC Emissions Last Reviewed 6/15/2016 DE-SC0011884 Goal The project goal is to develop an innovative, non-catalytic high destruction efficiency, and low fuel consumption volatile organic compounds (VOC) incinerator to reduce VOCs from condensate tanks and other low heat value waste gas streams. Performers Advanced Cooling Technologies (ACT), Inc., Lancaster, PA 17601 Background VOC emissions from various sources (oil and gas

  2. sc0013810-amethyst-research | netl.doe.gov

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    Unconventional Resources Development of a New Analytical Technology in Support of Oil and Natural Gas Extraction Last Reviewed 6/10/2016 DE-SC0013810 Goal The project goal is to develop a powerful suite of new analytical techniques derived from ion beam capabilities. The intention is to contribute to the nation's oil and gas exploration sector by offering a new and unique analytical toolset. Ion beam analysis will provide enhanced geochemical and mineralogical data sets for extracting oil and

  3. Jobs | U.S. DOE Office of Science (SC)

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  20. Contact | U.S. DOE Office of Science (SC)

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    Contact Human Subjects Protection Program (HSPP) HSPP Home About Institutional Review Boards (IRBs) Education and Resources Regulations and Requirements Glossary Abbreviations Contact BER Home Contact Information Human Subjects Protection Program U.S. Department of Energy SC-23/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 Contact Print Text Size: A A A FeedbackShare Page Name Email Address * Subject * Type of Inquiry or Feedback IRB Review Requirements Resource Materials

  1. Current Projects | U.S. DOE Office of Science (SC)

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    Science Laboratories Infrastructure (SLI) Program » Current Projects Operations Program Management (OPM) OPM Home About Science Laboratories Infrastructure (SLI) Program Current Projects Safeguards & Security (S&S) Program Sustainability Contact Information Operations Program Management U.S. Department of Energy SC-33/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-8429 F: (301) 903-7047 More Information » Science Laboratories Infrastructure (SLI)

  2. Doug Baltz | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Doug Baltz Albert Einstein Distinguished Educator Fellowship (AEF) Program Einstein Fellowship Home Eligibility Benefits Obligations How to Apply Key Dates Frequently Asked Questions Fellows Central Current Fellows Alumni Fellows Official AEF Logos Contact WDTS Home Current Fellows Doug Baltz Print Text Size: A A A FeedbackShare Page Doug Baltz Fellowship Placement: National Science Foundation Hometown: Royal Oak, MI Douglas Baltz has been an AP Physics and STEM teacher for over 20 years at

  3. DOE - Office of Legacy Management -- Baker-Perkins Co - MI 13

    Office of Legacy Management (LM)

    Baker-Perkins Co - MI 13 FUSRAP Considered Sites Site: Baker-Perkins Co (MI 13) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Saginaw , Michigan MI.13-1 Evaluation Year: 1991 MI.13-1 MI.13-2 Site Operations: Small scale oxide mixing demonstrations and testing in May, 1956. MI.13-2 Site Disposition: Eliminated - Potential for contamination remote based on limited scope of activities at the site MI.13-3 Radioactive Materials Handled: Yes

  4. DOE - Office of Legacy Management -- Revere Copper and Brass Co - MI 04

    Office of Legacy Management (LM)

    Revere Copper and Brass Co - MI 04 FUSRAP Considered Sites Site: REVERE COPPER AND BRASS CO. ( MI.04 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: Revere Copper and Brass MI.04-1 Location: 5851 West Jefferson Street , Detroit , Michigan MI.04-1 Evaluation Year: 1990 MI.04-2 Site Operations: Extrusion of tuballoy rods, myrnalloy rods and beryllium shapes in the 1940s. MI.04-3 MI.04-4 Site Disposition: Eliminated - Radiation levels below criteria

  5. Electronic and optical properties of ScN and (Sc,Mn)N thin films deposited by reactive DC-magnetron sputtering

    SciTech Connect (OSTI)

    Saha, Bivas; Birck Nanotechnology Center, Purdue University, West Lafayette, Indiana 47907 ; Naik, Gururaj; Boltasseva, Alexandra; School of Electrical and Computer Engineering, Purdue University, West Lafayette, Indiana 47907 ; Drachev, Vladimir P.; School of Electrical and Computer Engineering, Purdue University, West Lafayette, Indiana 47907; Department of Physics, University of North Texas, Denton, Texas 76203 ; Marinero, Ernesto E.; Sands, Timothy D.; Birck Nanotechnology Center, Purdue University, West Lafayette, Indiana 47907; School of Electrical and Computer Engineering, Purdue University, West Lafayette, Indiana 47907

    2013-08-14

    Scandium nitride (ScN) is a rocksalt semiconductor that has attracted significant attention from various researchers for a diverse range of applications. Motivated by the prospect of using its interesting electronic structure for optoelectronic and dilute magnetic semiconductor applications, we present detailed studies of the electronic transport and optical properties of ScN and its alloys with manganese nitride (MnN). Our results suggest (a) dilute manganese doping in ScN compensates for the high n-type carrier concentrations arising due to oxygen impurities and (b) an n-type to p-type carrier type transition occurs at a composition between 5.8% and 11% Mn on Sc sites. In terms of its optical properties, our analysis clearly indicates direct and indirect bandgap absorption edges of ScN located at 2.04 eV and 1.18 eV, respectively. In addition to the direct gap absorption edge, (Sc,Mn)N samples also show Mn-defect induced electronic absorption. Photoluminescence measurements at room temperature from ScN films exhibit a yellowish-green emission corresponding to direct gap radiative recombination. Direct gap recombination is not expected given the smaller indirect gap. A possible role of high excitation intensities in suppressing relaxation and recombination across the indirect bandgap is suspected. Raman spectroscopic and ellipsometric characterization of the dielectric permittivities of ScN and (Sc,Mn)N are also presented to assist in understanding the potential of ScN for optoelectronic applications.

  6. miR-17 inhibitor suppressed osteosarcoma tumor growth and metastasis via increasing PTEN expression

    SciTech Connect (OSTI)

    Gao, Yong; Luo, Ling-hui; Li, Shuai; Yang, Cao

    2014-02-07

    Highlights: • miR-17 was increased in OS tissues and cell lines. • Inhibition of miR-17 suppressed OS cell proliferation. • Inhibition of miR-17 suppressed OS cell migration and invasion. • PTEN was a target of miR-17. • miR-17 was negatively correlated with PTEN in OS tissues. - Abstract: MicroRNAs (miRNAs) play essential roles in cancer development and progression. Here, we investigated the role of miR-17 in the progression and metastasis of osteosarcoma (OS). miR-17 was frequently increased in OS tissues and cell lines. Inhibition of miR-17 in OS cell lines substantially suppressed cell proliferation, migration, and invasion. Phosphatase and tensin homolog (PTEN) was identified as a target of miR-17, and ectopic expression of miR-17 inhibited PTEN by direct binding to its 3′-untranslated region (3′-UTR). Expression of miR-17 was negatively correlated with PTEN in OS tissues. Together, these findings indicate that miR-17 acts as an oncogenic miRNA and may contribute to the progression and metastasis of OS, suggesting miR-17 as a potential novel diagnostic and therapeutic target of OS.

  7. External Links | U.S. DOE Office of Science (SC)

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    External Links Budget Budget Home About Budget by Program GAO Audit Reports External Links Contact Information Budget U.S. Department of Energy SC-41/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3541 F: (301) 903-9524 More Information » External Links Print Text Size: A A A FeedbackShare Page Office of Management and Budget (OMB) External link OMB Budget Documents External link CFO Budget Office U.S. Senate External link U.S. House of Representatives External

  8. FY 1987 | U.S. DOE Office of Science (SC)

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    7 Budget Budget Home About Budget by Program GAO Audit Reports External Links Contact Information Budget U.S. Department of Energy SC-41/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3541 F: (301) 903-9524 More Information » FY 1987 Print Text Size: A A A FeedbackShare Page Fiscal Year 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 FY 1987 Budget Request to

  9. FY 1988 | U.S. DOE Office of Science (SC)

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  11. FY 1990 | U.S. DOE Office of Science (SC)

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    0 Budget Budget Home About Budget by Program GAO Audit Reports External Links Contact Information Budget U.S. Department of Energy SC-41/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3541 F: (301) 903-9524 More Information » FY 1990 Print Text Size: A A A FeedbackShare Page Fiscal Year 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 FY 1990 Budget Request to

  12. FY 1991 | U.S. DOE Office of Science (SC)

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    1 Budget Budget Home About Budget by Program GAO Audit Reports External Links Contact Information Budget U.S. Department of Energy SC-41/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3541 F: (301) 903-9524 More Information » FY 1991 Print Text Size: A A A FeedbackShare Page Fiscal Year 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 FY 1991 Budget Request to

  13. FY 1992 | U.S. DOE Office of Science (SC)

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    2 Budget Budget Home About Budget by Program GAO Audit Reports External Links Contact Information Budget U.S. Department of Energy SC-41/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3541 F: (301) 903-9524 More Information » FY 1992 Print Text Size: A A A FeedbackShare Page Fiscal Year 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 FY 1992 Budget Request to

  14. FY 1993 | U.S. DOE Office of Science (SC)

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  15. FY 1994 | U.S. DOE Office of Science (SC)

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    4 Budget Budget Home About Budget by Program GAO Audit Reports External Links Contact Information Budget U.S. Department of Energy SC-41/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3541 F: (301) 903-9524 More Information » FY 1994 Print Text Size: A A A FeedbackShare Page Fiscal Year 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 FY 1994 Budget Request to

  16. FY 1995 | U.S. DOE Office of Science (SC)

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    5 Budget Budget Home About Budget by Program GAO Audit Reports External Links Contact Information Budget U.S. Department of Energy SC-41/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3541 F: (301) 903-9524 More Information » FY 1995 Print Text Size: A A A FeedbackShare Page Fiscal Year 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 FY 1995 Budget Request to

  17. FY 1996 | U.S. DOE Office of Science (SC)

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  18. FY 1997 | U.S. DOE Office of Science (SC)

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    7 Budget Budget Home About Budget by Program GAO Audit Reports External Links Contact Information Budget U.S. Department of Energy SC-41/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3541 F: (301) 903-9524 More Information » FY 1997 Print Text Size: A A A FeedbackShare Page Fiscal Year 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 1987 FY 1997 Budget Request to

  19. FY 1998 | U.S. DOE Office of Science (SC)

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  20. FY 1999 | U.S. DOE Office of Science (SC)

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  1. Benefits | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Arthur H. Rosenfeld, 2005 The Enrico Fermi Award Fermi Award Home Nomination & Selection Guidelines Award Laureates 2010's 2000's 1990's 1980's 1970's 1960's 1950's Ceremony The Life of Enrico Fermi Contact Information The Enrico Fermi Award U.S. Department of Energy SC-2/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-2411 E: Email Us 2000's Arthur H. Rosenfeld, 2005 Print Text Size: A A A FeedbackShare Page Citation For a lifetime of achievement ranging

  2. Key Dates | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Kenneth N. Raymond, 1984 The Ernest Orlando Lawrence Award Lawrence Award Home Nomination & Selection Guidelines Award Laureates 2010's 2000's 1990's 1980's 1970's 1960's Ceremony The Life of Ernest Orlando Lawrence Contact Information The Ernest Orlando Lawrence Award U.S. Department of Energy SC-2/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-2411 E: Email Us 1980's Kenneth N. Raymond, 1984 Print Text Size: A A A FeedbackShare Page Chemistry: For elegant

  3. Program Contacts | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Pavel Bochev, 2014 The Ernest Orlando Lawrence Award Lawrence Award Home Nomination & Selection Guidelines Award Laureates 2010's 2000's 1990's 1980's 1970's 1960's Ceremony The Life of Ernest Orlando Lawrence Contact Information The Ernest Orlando Lawrence Award U.S. Department of Energy SC-2/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-2411 E: Email Us 2010's Pavel Bochev, 2014 Print Text Size: A A A FeedbackShare Page Computer, Information, and

  4. Volunteers | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Sheldon Datz, 2000 The Enrico Fermi Award Fermi Award Home Nomination & Selection Guidelines Award Laureates 2010's 2000's 1990's 1980's 1970's 1960's 1950's Ceremony The Life of Enrico Fermi Contact Information The Enrico Fermi Award U.S. Department of Energy SC-2/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-2411 E: Email Us 2000's Sheldon Datz, 2000 Print Text Size: A A A FeedbackShare Page Citation For his career in chemistry and atomic physics, the

  5. 2012 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    2 High Energy Physics (HEP) HEP Home About Research Facilities Science Highlights Benefits of HEP Funding Opportunities Advisory Committees Community Resources Contact Information High Energy Physics U.S. Department of Energy SC-25/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3624 F: (301) 903-2597 E: Email Us More Information » Science Highlights 2012 Print Text Size: A A A FeedbackShare Page Filter by Performer Or press Esc Key to close. close Select all

  6. 2013 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    3 High Energy Physics (HEP) HEP Home About Research Facilities Science Highlights Benefits of HEP Funding Opportunities Advisory Committees Community Resources Contact Information High Energy Physics U.S. Department of Energy SC-25/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3624 F: (301) 903-2597 E: Email Us More Information » Science Highlights 2013 Print Text Size: A A A FeedbackShare Page Filter by Performer Or press Esc Key to close. close Select all

  7. 2014 | U.S. DOE Office of Science (SC)

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    4 High Energy Physics (HEP) HEP Home About Research Facilities Science Highlights Benefits of HEP Funding Opportunities Advisory Committees Community Resources Contact Information High Energy Physics U.S. Department of Energy SC-25/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3624 F: (301) 903-2597 E: Email Us More Information » Science Highlights 2014 Print Text Size: A A A FeedbackShare Page Filter by Performer Or press Esc Key to close. close Select all

  8. 2015 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    5 High Energy Physics (HEP) HEP Home About Research Facilities Science Highlights Benefits of HEP Funding Opportunities Advisory Committees Community Resources Contact Information High Energy Physics U.S. Department of Energy SC-25/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3624 F: (301) 903-2597 E: Email Us More Information » Science Highlights 2015 Print Text Size: A A A FeedbackShare Page Filter by Performer Or press Esc Key to close. close Select all

  9. Staff Directories | U.S. DOE Office of Science (SC)

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    EPSCoR Home » About » Staff Listings/Contact Information Experimental Program to Stimulate Competitive Research (EPSCoR) EPSCoR Home About Staff Listings/Contact Information Current Awards How to Apply Manage Your Grant Recent News SBIR/STTR Home BES Home Contact Information Experimental Program to Stimulate Competitive Research U.S. Department of Energy SC-22/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-9830 F: (301) 903-9513 E: Email Us More Information »

  10. DOE/SC Lehman Review of US ITER Project, USIPO,

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    SC Lehman Review of US ITER Project, USIPO, Oak Ridge, Tennessee, April 5-7, 2011 - Ned Sauthoff Project Manager, US ITER INSIDE: ITER Site Progress Secret City View from DOE US Project Highlights Engaging Industry New PPPL Head of ITER Department PPPL to Cadarache New Division Director Positions Open at US ITER Upcoming Events ORNL 2011-G00858/jpp It has been a busy season for US ITER, as the team positions for fabrication in late-FY 12 and FY 13. Our priorities remain completing designs,

  11. SLI Budget | U.S. DOE Office of Science (SC)

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    SLI Budget Budget Budget Home About Budget by Program ASCR Budget BES Budget BER Budget FES Budget HEP Budget NP Budget WDTS Budget SLI Budget S&S Budget SCPD Budget GAO Audit Reports External Links Contact Information Budget U.S. Department of Energy SC-41/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3541 F: (301) 903-9524 More Information » Budget by Program SLI Budget Print Text Size: A A A FeedbackShare Page The following links contain SLI's budget

  12. de-sc0010209 | netl.doe.gov

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    High Capacity Sorbent and Process for CO2 Capture Project No.: DE-SC0010209 In this Small Business Innovation Research/Small Business Technology Transfer (SBIR/STTR) project, Envergex LLC, in collaboration with the University of North Dakota, will evaluate an Enhanced Process for Capture of CO2 using Hybrid Sorption (E-CACHYS(tm)) that combines a low-cost, high-capacity sorbent and a novel process design. The principal objectives are to achieve a quantum increase in the capacity of hybrid

  13. About | U.S. DOE Office of Science (SC)

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    About Budget Budget Home About Organization Chart .pdf file (59KB) Jobs Budget by Program GAO Audit Reports External Links Contact Information Budget U.S. Department of Energy SC-41/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3541 F: (301) 903-9524 More Information » About Print Text Size: A A A FeedbackShare Page Welcome to the Office of Budget in the Office of Science. Our office provides financial management support to the programs in the Office of

  14. 1950's | U.S. DOE Office of Science (SC)

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    's The Enrico Fermi Award Fermi Award Home Nomination & Selection Guidelines Award Laureates 2010's 2000's 1990's 1980's 1970's 1960's 1950's Ceremony The Life of Enrico Fermi Contact Information The Enrico Fermi Award U.S. Department of Energy SC-2/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-2411 E: Email Us Award Laureates 1950's Print Text Size: A A A FeedbackShare Page Laureates Glenn I. Seaborg, 1959 Eugene P. Wigner, 1958 Ernest 0. Lawrence, 1957

  15. 1960's | U.S. DOE Office of Science (SC)

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    's The Enrico Fermi Award Fermi Award Home Nomination & Selection Guidelines Award Laureates 2010's 2000's 1990's 1980's 1970's 1960's 1950's Ceremony The Life of Enrico Fermi Contact Information The Enrico Fermi Award U.S. Department of Energy SC-2/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-2411 E: Email Us Award Laureates 1960's Print Text Size: A A A FeedbackShare Page Laureates Walter H. Zinn, 1969 John A. Wheeler, 1968 Otto Hahn, 1966 Lise Meitner,

  16. 1960's | U.S. DOE Office of Science (SC)

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    's The Ernest Orlando Lawrence Award Lawrence Award Home Nomination & Selection Guidelines Award Laureates 2010's 2000's 1990's 1980's 1970's 1960's Ceremony The Life of Ernest Orlando Lawrence Contact Information The Ernest Orlando Lawrence Award U.S. Department of Energy SC-2/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-2411 E: Email Us Award Laureates 1960's Print Text Size: A A A FeedbackShare Page 1969 Geoffrey F. Chew Don T. Cromer Ely M. Gelbard F.

  17. 1970's | U.S. DOE Office of Science (SC)

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    's The Enrico Fermi Award Fermi Award Home Nomination & Selection Guidelines Award Laureates 2010's 2000's 1990's 1980's 1970's 1960's 1950's Ceremony The Life of Enrico Fermi Contact Information The Enrico Fermi Award U.S. Department of Energy SC-2/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-2411 E: Email Us Award Laureates 1970's Print Text Size: A A A FeedbackShare Page Laureates Wolfgang K.H. Panofsky, 1978 Harold M. Agnew, 1978 William L. Russell,

  18. 1970's | U.S. DOE Office of Science (SC)

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    's The Ernest Orlando Lawrence Award Lawrence Award Home Nomination & Selection Guidelines Award Laureates 2010's 2000's 1990's 1980's 1970's 1960's Ceremony The Life of Ernest Orlando Lawrence Contact Information The Ernest Orlando Lawrence Award U.S. Department of Energy SC-2/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-2411 E: Email Us Award Laureates 1970's Print Text Size: A A A FeedbackShare Page 1977 James D. Bjorken John L. Emmett F. William

  19. 1980's | U.S. DOE Office of Science (SC)

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    's The Enrico Fermi Award Fermi Award Home Nomination & Selection Guidelines Award Laureates 2010's 2000's 1990's 1980's 1970's 1960's 1950's Ceremony The Life of Enrico Fermi Contact Information The Enrico Fermi Award U.S. Department of Energy SC-2/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-2411 E: Email Us Award Laureates 1980's Print Text Size: A A A FeedbackShare Page Laureates Richard B. Setlow, 1988 Victor F. Weisskopf, 1988 Luis Alvarez, 1987

  20. 1990's | U.S. DOE Office of Science (SC)

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    's The Ernest Orlando Lawrence Award Lawrence Award Home Nomination & Selection Guidelines Award Laureates 2010's 2000's 1990's 1980's 1970's 1960's Ceremony The Life of Ernest Orlando Lawrence Contact Information The Ernest Orlando Lawrence Award U.S. Department of Energy SC-2/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-2411 E: Email Us Award Laureates 1990's Print Text Size: A A A FeedbackShare Page 1998 Dan Gabriel Cacuci Joanna S. Fowler Laura H.

  1. HEP Budget | U.S. DOE Office of Science (SC)

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    HEP Budget Budget Budget Home About Budget by Program ASCR Budget BES Budget BER Budget FES Budget HEP Budget NP Budget WDTS Budget SLI Budget S&S Budget SCPD Budget GAO Audit Reports External Links Contact Information Budget U.S. Department of Energy SC-41/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3541 F: (301) 903-9524 More Information » Budget by Program HEP Budget Print Text Size: A A A FeedbackShare Page The following links contain HEP's budget

  2. Jobs | U.S. DOE Office of Science (SC)

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    About » Jobs Budget Budget Home About Organization Chart .pdf file (59KB) Jobs Budget by Program GAO Audit Reports External Links Contact Information Budget U.S. Department of Energy SC-41/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-3541 F: (301) 903-9524 More Information » About Jobs Print Text Size: A A A Subscribe FeedbackShare Page Current Open Federal Positions The Office of Budget is located in Germantown, Maryland. All open federal positions listed

  3. Ceremony | U.S. DOE Office of Science (SC)

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    Ceremony The Ernest Orlando Lawrence Award Lawrence Award Home Nomination & Selection Guidelines Award Laureates Ceremony The Life of Ernest Orlando Lawrence Contact Information The Ernest Orlando Lawrence Award U.S. Department of Energy SC-2/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-2411 E: Email Us Ceremony Print Text Size: A A A FeedbackShare Page RSVP RSVP for the ceremony. The E.O. Lawrence Award honors mid-career scientists for their exceptional

  4. 2000's | U.S. DOE Office of Science (SC)

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    's The Enrico Fermi Award Fermi Award Home Nomination & Selection Guidelines Award Laureates 2010's 2000's 1990's 1980's 1970's 1960's 1950's Ceremony The Life of Enrico Fermi Contact Information The Enrico Fermi Award U.S. Department of Energy SC-2/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-2411 E: Email Us Award Laureates 2000's Print Text Size: A A A FeedbackShare Page Laureates John Bannister Goodenough, 2009 Siegfried S. Hecker, 2009 Arthur H.

  5. 2000's | U.S. DOE Office of Science (SC)

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    's The Ernest Orlando Lawrence Award Lawrence Award Home Nomination & Selection Guidelines Award Laureates 2010's 2000's 1990's 1980's 1970's 1960's Ceremony The Life of Ernest Orlando Lawrence Contact Information The Ernest Orlando Lawrence Award U.S. Department of Energy SC-2/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-2411 E: Email Us Award Laureates 2000's Print Text Size: A A A FeedbackShare Page 2009 Joan F. Brennecke William Dorland Omar Hurricane

  6. 2010 | U.S. DOE Office of Science (SC)

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    0 The Enrico Fermi Award Fermi Award Home Nomination & Selection Guidelines Award Laureates 2010's 2000's 1990's 1980's 1970's 1960's 1950's Ceremony The Life of Enrico Fermi Contact Information The Enrico Fermi Award U.S. Department of Energy SC-2/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-2411 E: Email Us 2010's 2010 Print Text Size: A A A FeedbackShare Page On May 7, 2012 it was conferred upon two exceptional scientists: Dr. Mildred Dresselhaus,

  7. 2010's | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    's The Enrico Fermi Award Fermi Award Home Nomination & Selection Guidelines Award Laureates 2010's 2000's 1990's 1980's 1970's 1960's 1950's Ceremony The Life of Enrico Fermi Contact Information The Enrico Fermi Award U.S. Department of Energy SC-2/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-2411 E: Email Us Award Laureates 2010's Print Text Size: A A A FeedbackShare Page 2010 Mildred S. Dresselhaus, 2010 Burton Richter, 2010 Ceremony Recap » 2013 Allen

  8. 2011 Ceremony | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    1 Ceremony The Ernest Orlando Lawrence Award Lawrence Award Home Nomination & Selection Guidelines Award Laureates 2010's 2000's 1990's 1980's 1970's 1960's Ceremony The Life of Ernest Orlando Lawrence Contact Information The Ernest Orlando Lawrence Award U.S. Department of Energy SC-2/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-2411 E: Email Us 2010's 2011 Ceremony Print Text Size: A A A FeedbackShare Page Watch the ceremony here. Javascript must be

  9. 2013 Ceremony | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    3 Ceremony The Ernest Orlando Lawrence Award Lawrence Award Home Nomination & Selection Guidelines Award Laureates 2010's 2000's 1990's 1980's 1970's 1960's Ceremony The Life of Ernest Orlando Lawrence Contact Information The Ernest Orlando Lawrence Award U.S. Department of Energy SC-2/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-2411 E: Email Us 2010's 2013 Ceremony Print Text Size: A A A FeedbackShare Page On June 24, 2014 The Ernest Orlando Lawrence

  10. 2013 | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    3 The Enrico Fermi Award Fermi Award Home Nomination & Selection Guidelines Award Laureates 2010's 2000's 1990's 1980's 1970's 1960's 1950's Ceremony The Life of Enrico Fermi Contact Information The Enrico Fermi Award U.S. Department of Energy SC-2/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-2411 E: Email Us 2010's 2013 Print Text Size: A A A FeedbackShare Page On February 3, 2014 it was conferred upon two exceptional scientists: Dr. Allen J. Bard,

  11. 2014 Ceremony | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    4 Ceremony The Ernest Orlando Lawrence Award Lawrence Award Home Nomination & Selection Guidelines Award Laureates 2010's 2000's 1990's 1980's 1970's 1960's Ceremony The Life of Ernest Orlando Lawrence Contact Information The Ernest Orlando Lawrence Award U.S. Department of Energy SC-2/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-2411 E: Email Us 2010's 2014 Ceremony Print Text Size: A A A FeedbackShare Page On July 23, 2015 The Ernest Orlando Lawrence

  12. 2014 | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    4 The Enrico Fermi Award Fermi Award Home Nomination & Selection Guidelines Award Laureates 2010's 2000's 1990's 1980's 1970's 1960's 1950's Ceremony The Life of Enrico Fermi Contact Information The Enrico Fermi Award U.S. Department of Energy SC-2/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-2411 E: Email Us 2010's 2014 Print Text Size: A A A FeedbackShare Page On October 20, 2015 it was conferred upon two exceptional scientists: Dr. Claudio Pellegrini,

  13. Current Awards | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Current Awards Experimental Program to Stimulate Competitive Research (EPSCoR) EPSCoR Home About Current Awards How to Apply Manage Your Grant Recent News SBIR/STTR Home BES Home Contact Information Experimental Program to Stimulate Competitive Research U.S. Department of Energy SC-22/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-9830 F: (301) 903-9513 E: Email Us More Information » Current Awards Print Text Size: A A A FeedbackShare Page Abstracts for

  14. Department of Energy | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Department of Energy Project Assessment (OPA) OPA Home About Project Management Processes and Procedures Department of Energy Office of Science Various Project Management Reports Cost & Contingency EDIA Escalation Rates Earned Value Management System (EVMS) Certifications Awards Lessons Learned Tools & Resources SC Projects Other Links SC Federal Project Directors (FPD) and FPD Resources Contact Information Project Assessment U.S. Department of Energy SC-28/Germantown Building 1000

  15. FY 2006 SC Laboratory Performance Report Cards | U.S. DOE Office of Science

    Office of Science (SC) Website

    (SC) 6 SC Laboratory Performance Report Cards Laboratory Policy (LP) LP Home About Laboratory Appraisal Process FY 2015 Report Cards FY 2014 Report Cards FY 2013 Report Cards Report Card Archives Laboratory Planning Process Laboratory Directed Research and Development (LDRD) Management & Operating (M&O) Contracts Technology Transfer Strategic Partnership Projects (SPP) Contact Information Laboratory Policy U.S. Department of Energy SC-32/Forrestal Building 1000 Independence Ave., SW

  16. FY 2007 SC Laboratory Performance Report Cards | U.S. DOE Office of Science

    Office of Science (SC) Website

    (SC) 7 SC Laboratory Performance Report Cards Laboratory Policy (LP) LP Home About Laboratory Appraisal Process FY 2015 Report Cards FY 2014 Report Cards FY 2013 Report Cards Report Card Archives Laboratory Planning Process Laboratory Directed Research and Development (LDRD) Management & Operating (M&O) Contracts Technology Transfer Strategic Partnership Projects (SPP) Contact Information Laboratory Policy U.S. Department of Energy SC-32/Forrestal Building 1000 Independence Ave., SW

  17. FY 2008 SC Laboratory Performance Report Cards | U.S. DOE Office of Science

    Office of Science (SC) Website

    (SC) 8 SC Laboratory Performance Report Cards Laboratory Policy (LP) LP Home About Laboratory Appraisal Process FY 2015 Report Cards FY 2014 Report Cards FY 2013 Report Cards Report Card Archives Laboratory Planning Process Laboratory Directed Research and Development (LDRD) Management & Operating (M&O) Contracts Technology Transfer Strategic Partnership Projects (SPP) Contact Information Laboratory Policy U.S. Department of Energy SC-32/Forrestal Building 1000 Independence Ave., SW

  18. FY 2009 SC Laboratory Performance Report Cards | U.S. DOE Office of Science

    Office of Science (SC) Website

    (SC) 9 SC Laboratory Performance Report Cards Laboratory Policy (LP) LP Home About Laboratory Appraisal Process FY 2015 Report Cards FY 2014 Report Cards FY 2013 Report Cards Report Card Archives Laboratory Planning Process Laboratory Directed Research and Development (LDRD) Management & Operating (M&O) Contracts Technology Transfer Strategic Partnership Projects (SPP) Contact Information Laboratory Policy U.S. Department of Energy SC-32/Forrestal Building 1000 Independence Ave., SW

  19. FY 2010 SC Laboratory Performance Report Cards | U.S. DOE Office of Science

    Office of Science (SC) Website

    (SC) 0 SC Laboratory Performance Report Cards Laboratory Policy (LP) LP Home About Laboratory Appraisal Process FY 2015 Report Cards FY 2014 Report Cards FY 2013 Report Cards Report Card Archives Laboratory Planning Process Laboratory Directed Research and Development (LDRD) Management & Operating (M&O) Contracts Technology Transfer Strategic Partnership Projects (SPP) Contact Information Laboratory Policy U.S. Department of Energy SC-32/Forrestal Building 1000 Independence Ave., SW

  20. FY 2011 SC Laboratory Performance Report Cards | U.S. DOE Office of Science

    Office of Science (SC) Website

    (SC) 1 SC Laboratory Performance Report Cards Laboratory Policy (LP) LP Home About Laboratory Appraisal Process FY 2015 Report Cards FY 2014 Report Cards FY 2013 Report Cards Report Card Archives Laboratory Planning Process Laboratory Directed Research and Development (LDRD) Management & Operating (M&O) Contracts Technology Transfer Strategic Partnership Projects (SPP) Contact Information Laboratory Policy U.S. Department of Energy SC-32/Forrestal Building 1000 Independence Ave., SW

  1. FY 2012 SC Laboratory Performance Report Cards | U.S. DOE Office of Science

    Office of Science (SC) Website

    (SC) 2 SC Laboratory Performance Report Cards Laboratory Policy (LP) LP Home About Laboratory Appraisal Process FY 2015 Report Cards FY 2014 Report Cards FY 2013 Report Cards Report Card Archives Laboratory Planning Process Laboratory Directed Research and Development (LDRD) Management & Operating (M&O) Contracts Technology Transfer Strategic Partnership Projects (SPP) Contact Information Laboratory Policy U.S. Department of Energy SC-32/Forrestal Building 1000 Independence Ave., SW

  2. Various Project Management Reports | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Various Project Management Reports Project Assessment (OPA) OPA Home About Project Management Processes and Procedures Department of Energy Office of Science Various Project Management Reports Cost & Contingency EDIA Escalation Rates Earned Value Management System (EVMS) Certifications Awards Lessons Learned Tools & Resources SC Projects Other Links SC Federal Project Directors (FPD) and FPD Resources Contact Information Project Assessment U.S. Department of Energy SC-28/Germantown

  3. Project Assessment (OPA) Homepage | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Programs » OPA Home Project Assessment (OPA) OPA Home About Project Management SC Projects Other Links SC Federal Project Directors (FPD) and FPD Resources Contact Information Project Assessment U.S. Department of Energy SC-28/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-4840 F: (301) 903-8520 E: Email Us Federal Project Director of the Year Mr. Frank Crescenzo, Federal Project Director for NSLS-II at BNL For demonstrating exceptional leadership and project

  4. Processes & Procedures | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Processes and Procedures Project Assessment (OPA) OPA Home About Project Management Processes and Procedures Department of Energy Office of Science Various Project Management Reports Cost & Contingency EDIA Escalation Rates Earned Value Management System (EVMS) Certifications Awards Lessons Learned Tools & Resources SC Projects Other Links SC Federal Project Directors (FPD) and FPD Resources Contact Information Project Assessment U.S. Department of Energy SC-28/Germantown Building 1000

  5. Cost & Contingency | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Cost & Contingency Project Assessment (OPA) OPA Home About Project Management Processes and Procedures Cost & Contingency EDIA Escalation Rates Earned Value Management System (EVMS) Certifications Awards Lessons Learned Tools & Resources SC Projects Other Links SC Federal Project Directors (FPD) and FPD Resources Contact Information Project Assessment U.S. Department of Energy SC-28/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301) 903-4840 F: (301)

  6. New Mexico Regions | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Mexico Regions National Science Bowl (NSB) NSB Home About High School High School ... WDTS Home Contact Information National Science Bowl U.S. Department of Energy SC-27 ...

  7. SC Laboratory Performance Report Card Archives | U.S. DOE Office...

    Office of Science (SC) Website

    SC Laboratory Performance Report Card Archives Laboratory Policy (LP) LP Home About Laboratory Appraisal Process FY 2015 Report Cards FY 2014 Report Cards FY 2013 Report Cards ...

  8. Privacy Act Advisory | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Freedom of Information ActPrivacy Act Officer U.S. Department of Energy SC Integrated ... to FOIA requests; to maintain case files to comply with records disposal ...

  9. Strong irradiation tolerance to amorphization in delta-Sc4Ti3O12...

    Office of Scientific and Technical Information (OSTI)

    Additional Journal Information: Journal Volume: 459; Journal Issue: C; Journal ID: ISSN 0022-3115 Publisher: Elsevier Sponsoring Org: USDOE Office of Science (SC), Basic Energy ...

  10. Accelerator R&D Stewardship | U.S. DOE Office of Science (SC...

    Office of Science (SC) Website

    High Energy Physics (HEP) HEP Home About Research Science ... Accelerator R&D to User Needs Workshop Reports Facilities ... SC programs, including Basic Energy Sciences (BES), ...

  11. Microsoft Word - CO2SC-Extended-Abstract_Xu_v1-1.doc

    Office of Scientific and Technical Information (OSTI)

    CO2SC Symposium 2006 Lawrence Berkeley National Laboratory, Berkeley, California, March ... Berkeley National Laboratory Berkeley, California 94506, USA e-mail: TianfuXu@lbl.gov ...

  12. Policies and Processes | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    User Facilities User Facilities Home User Facilities at a Glance User Resources User Statistics Policies and Processes Definition Designation Process Official List of SC User...

  13. 2014 Annual EM/NE/SC SQA Support Group Meeting | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    4 Annual EM/NE/SC SQA Support Group Meeting 2014 Annual EM/NE/SC SQA Support Group Meeting 2014 Annual EM/NE/SC SQA Support Group Meeting The 2014 Annual Face-to-Face Meeting of the Environmental Management (EM), Nuclear Energy (NE), and Science (SC) Software Quality Assurance (SQA) Support Group (SG) was held May 6-8, 2014. This meeting was hosted by the Office of Safeguards, Security and Emergency Services (OSSES) at the Savannah River Site (SRS). The Chief of Nuclear Safety (CNS) sponsors

  14. 2015 Annual EM/NE/SC SQA Support Group Meeting | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5 Annual EM/NE/SC SQA Support Group Meeting 2015 Annual EM/NE/SC SQA Support Group Meeting 2015 Annual EM/NE/SC SQA Support Group Meeting The Chief of Nuclear Safety (CNS) formed the Environmental Management (EM), Nuclear Energy (NE), and Science (SC) Software Quality Assurance (SQA) Support Group (SG) in March 2007. The first Annual Meeting was held August 2008. The 8th Annual Meeting will be held May 11-14, 2015. This year the Annual Meeting will be hosted by EM's Office of River Protection in

  15. Supercomputing on a Budget | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Nuclear Physics U.S. Department of Energy SC-26Germantown ... 2013. This single rack system houses two supercomputers: ... Computing, Networking, Storage and Analysis, Article No. ...

  16. Supercomputing on a Budget | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    U.S. Department of Energy SC-21Germantown Building ... 2013. This single rack system houses two supercomputers: ... Computing, Networking, Storage and Analysis, Article No. ...

  17. Texas AM Junior Science Bowl | U.S. DOE Office of Science (SC...

    Office of Science (SC) Website

    National Science Bowl U.S. Department of Energy SC-27 Forrestal Building 1000 ... County, TX Titus County, TX Tom Green County, TX Travis County, TX Trinity ...

  18. Universe in a (Blue) Bottle | U.S. DOE Office of Science (SC...

    Office of Science (SC) Website

    ... ASCR provided computer time through its "Early Science program". Additional funding was provided by SC's High Energy Physics (HEP) program and ANL's Laboratory Directed Research ...

  19. Joan F. Brennecke, 2009 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    The Ernest Orlando Lawrence Award U.S. Department of Energy SC-2Germantown Building 1000 ... and technological leadership in discovering new environmentally-benign, green chemistries

  20. Regional News Coverage 2015 | U.S. DOE Office of Science (SC...

    Office of Science (SC) Website

    National Science Bowl U.S. Department of Energy SC-27 Forrestal Building 1000 ... and Science in Kentucky, Bowling Green, KY .pdf file (18KB) The Westminster ...

  1. Other Participants 1997 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    National Science Bowl U.S. Department of Energy SC-27 Forrestal Building 1000 ... Grace M. Davis High School , Modesto , CA Green Valley High School , Henderson , NV ...

  2. Other Participants 1995 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    National Science Bowl U.S. Department of Energy SC-27 Forrestal Building 1000 ... , CA Fergus High School , Lewiston , MT Green Mountain High School, Lakewood, CO George ...

  3. My Hang V. Huynh, 2006 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    The Ernest Orlando Lawrence Award U.S. Department of Energy SC-2Germantown Building 1000 ... using coordination chemistry, including green primary explosives that contain no lead, ...

  4. Other Participants 2002 | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    ... Skyline High School , Idaho Falls, ID Skyview High School , Billings , MT Smoky Hill High School, Aurora, CO South Aiken High School , Aiken , SC Southside High School , Fort Smith ...

  5. MiR-218 Mediates tumorigenesis and metastasis: Perspectives and implications

    SciTech Connect (OSTI)

    Lu, Ying-fei; Zhang, Li; Waye, Mary Miu Yee; Fu, Wei-ming; Zhang, Jin-fang

    2015-05-15

    MicroRNAs (miRNAs) are a class of small non-coding RNAs that negatively regulate gene expression at the post-transcriptional level. As a highly conserved miRNA across a variety of species, microRNA-218 (miR-218) was found to play pivotal roles in tumorigenesis and progression. A group of evidence has demonstrated that miR-218 acts as a tumor suppressor by targeting many oncogenes related to proliferation, apoptosis and invasion. In this review, we provide a complex overview of miR-218, including its regulatory mechanisms, known functions in cancer and future challenges as a potential therapeutic target in human cancers. - Highlights: • miR-218 is frequently down regulated in multiple cancers. • miR-218 plays pivotal roles in carcinogenesis. • miR-218 mediates proliferation, apoptosis, metastasis, invasion, etc. • miR-218 mediates tumorigenesis and metastasis via multiple pathways.

  6. Tn-seq of Caulobacter crescentus under uranium stress reveals genes essential for detoxification and stress tolerance

    SciTech Connect (OSTI)

    Yung, Mimi C.; Park, Dan M.; Overton, K. Wesley; Blow, Matthew J.; Hoover, Cindi A.; Smit, John R.; Murray, Sean R.; Ricci, Dante P.; Christen, Beat; Bowman, Grant R.; Jiao, Yongqin

    2015-07-20

    Ubiquitous aquatic bacterium Caulobacter crescentus is highly resistant to uranium (U) and facilitates U biomineralization and thus holds promise as an agent of U bioremediation. In order to gain an understanding of how C. crescentus tolerates U, we employed transposon (Tn) mutagenesis paired with deep sequencing (Tn-seq) in a global screen for genomic elements required for U resistance. Of the 3,879 annotated genes in the C. crescentus genome, 37 were found to be specifically associated with fitness under U stress, 15 of which were subsequently tested through mutational analysis. Systematic deletion analysis revealed that mutants lacking outer membrane transporters (rsaFa and rsaFb), a stress-responsive transcription factor (cztR), or a ppGpp synthetase/hydrolase (spoT) exhibited a significantly lower survival rate under U stress. RsaFa and RsaFb, which are homologues of TolC in Escherichia coli, have previously been shown to mediate S-layer export. Transcriptional analysis revealed upregulation of rsaFa and rsaFb by 4- and 10-fold, respectively, in the presence of U. We additionally show that rsaFa mutants accumulated higher levels of U than the wild type, with no significant increase in oxidative stress levels. These results suggest a function for RsaFa and RsaFb in U efflux and/or maintenance of membrane integrity during U stress. In addition, we present data implicating CztR and SpoT in resistance to U stress. Together, our findings reveal novel gene targets that are key to understanding the molecular mechanisms of U resistance in C. crescentus.

  7. Annual Performance Evaluation of a Pair of Energy Efficient Houses (WC3 and WC4) in Oak Ridge, TN

    SciTech Connect (OSTI)

    Biswas, Kaushik; Christian, Jeffrey E; Gehl, Anthony C; Jackson, Roderick K; Boudreaux, Philip R

    2012-04-01

    Beginning in 2008, two pairs of energy-saver houses were built at Wolf Creek in Oak Ridge, TN. These houses were designed to maximize energy efficiency using new ultra-high-efficiency components emerging from ORNL s Cooperative Research and Development Agreement (CRADA) partners and others. The first two houses contained 3713 square feet of conditioned area and were designated as WC1 and WC2; the second pair consisted of 2721 square feet conditioned area with crawlspace foundation and they re called WC3 and WC4. This report is focused on the annual energy performance of WC3 and WC4, and how they compare against a previously benchmarked maximum energy efficient house of a similar footprint. WC3 and WC4 are both about 55-60% more efficient than traditional new construction. Each house showcases a different envelope system: WC3 is built with advanced framing featured cellulose insulation partially mixed with phase change materials (PCM); and WC4 house has cladding composed of an exterior insulation and finish system (EIFS). The previously benchmarked house was one of three built at the Campbell Creek subdivision in Knoxville, TN. This house (CC3) was designed as a transformation of a builder house (CC1) with the most advanced energy-efficiency features, including solar electricity and hot water, which market conditions are likely to permit within the 2012 2015 period. The builder house itself was representative of a standard, IECC 2006 code-certified, all-electric house built by the builder to sell around 2005 2008.

  8. Tn-seq of Caulobacter crescentus under uranium stress reveals genes essential for detoxification and stress tolerance

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Yung, Mimi C.; Park, Dan M.; Overton, K. Wesley; Blow, Matthew J.; Hoover, Cindi A.; Smit, John R.; Murray, Sean R.; Ricci, Dante P.; Christen, Beat; Bowman, Grant R.; et al

    2015-07-20

    Ubiquitous aquatic bacterium Caulobacter crescentus is highly resistant to uranium (U) and facilitates U biomineralization and thus holds promise as an agent of U bioremediation. In order to gain an understanding of how C. crescentus tolerates U, we employed transposon (Tn) mutagenesis paired with deep sequencing (Tn-seq) in a global screen for genomic elements required for U resistance. Of the 3,879 annotated genes in the C. crescentus genome, 37 were found to be specifically associated with fitness under U stress, 15 of which were subsequently tested through mutational analysis. Systematic deletion analysis revealed that mutants lacking outer membrane transporters (rsaFamore » and rsaFb), a stress-responsive transcription factor (cztR), or a ppGpp synthetase/hydrolase (spoT) exhibited a significantly lower survival rate under U stress. RsaFa and RsaFb, which are homologues of TolC in Escherichia coli, have previously been shown to mediate S-layer export. Transcriptional analysis revealed upregulation of rsaFa and rsaFb by 4- and 10-fold, respectively, in the presence of U. We additionally show that rsaFa mutants accumulated higher levels of U than the wild type, with no significant increase in oxidative stress levels. These results suggest a function for RsaFa and RsaFb in U efflux and/or maintenance of membrane integrity during U stress. In addition, we present data implicating CztR and SpoT in resistance to U stress. Together, our findings reveal novel gene targets that are key to understanding the molecular mechanisms of U resistance in C. crescentus.« less

  9. DOE - Office of Legacy Management -- Dow-Detroit Edison Project - MI 0-02

    Office of Legacy Management (LM)

    Dow-Detroit Edison Project - MI 0-02 FUSRAP Considered Sites Site: Dow-Detroit Edison Project (MI.0-02 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Detroit , Michigan MI.0-02-1 Evaluation Year: 1987 MI.0-02-1 Site Operations: Performed reference design work for a special fast breeder type reactor. MI.0-02-1 Site Disposition: Eliminated - No radioactive material handled at the site MI.0-02-1 Radioactive Materials Handled: No

  10. DOE - Office of Legacy Management -- Mitts-Merrill Co - MI 14

    Office of Legacy Management (LM)

    Mitts-Merrill Co - MI 14 FUSRAP Considered Sites Site: MITTS and MERRILL CO. (MI.14 ) Eliminated from consideration under FUSRAP Designated Name: Not Designated Alternate Name: Genessee Packing Co. MI.14-1 Location: Saginaw, Michigan MI.14-1 Evaluation Year: 1993 MI.14-2 Site Operations: Reduced thorium metal chunks into particle sized pieces on a small test scale during the mid-1950s. MI.14-1 Site Disposition: Eliminated - Potential for contamination considered remote based on limited quantity

  11. miRNA-205 affects infiltration and metastasis of breast cancer

    SciTech Connect (OSTI)

    Wang, Zhouquan; Department of Tumor, SenGong Hospital of Shaanxi, Xian 710300 ; Liao, Hehe; Deng, Zhiping; Yang, Po; Du, Ning; Zhanng, Yunfeng; Ren, Hong

    2013-11-08

    Highlights: We detected expression of miR-205 in breast cancer cell lines and tissue samples. We suggest miR-205 is downregulated in human breast cancer tissues and MCF7 cells. We suggest the lower expression of miR-205 play a role in breast cancer onset. These data suggest that miR-205 directly targets HER3 in human breast cancer. -- Abstract: Background: An increasing number of studies have shown that miRNAs are commonly deregulated in human malignancies, but little is known about the function of miRNA-205 (miR-205) in human breast cancer. The present study investigated the influence of miR-205 on breast cancer malignancy. Methods: The expression level of miR-205 in the MCF7 breast cancer cell line was determined by quantitative (q)RT-PCR. We then analyzed the expression of miR-205 in breast cancer and paired non-tumor tissues. Finally, the roles of miR-205 in regulating tumor proliferation, apoptosis, migration, and target gene expression were studied by MTT assay, flow cytometry, qRT-PCR, Western blotting and luciferase assay. Results: miR-205 was downregulated in breast cancer cells or tissues compared with normal breast cell lines or non-tumor tissues. Overexpression of miR-205 reduced the growth and colony-formation capacity of MCF7 cells by inducing apoptosis. Overexpression of miR-205 inhibited MCF7 cell migration and invasiveness. By bioinformation analysis, miR-205 was predicted to bind to the 3? untranslated regions of human epidermal growth factor receptor (HER)3 mRNA, and upregulation of miR-205 reduced HER3 protein expression. Conclusion: miR-205 is a tumor suppressor in human breast cancer by post-transcriptional inhibition of HER3 expression.

  12. Final Report for DOE Grant Number DE-SC0001481

    SciTech Connect (OSTI)

    Liang, Edison

    2013-12-02

    This report covers research activities, major results and publications supported by DE-SC-000-1481. This project was funded by the DOE OFES-NNSA HEDLP program. It was a joint research program between Rice University and the University of Texas at Austin. The physics of relativistic plasmas was investigated in the context of ultra-intense laser irradiation of high-Z solid targets. Laser experiments using the Texas Petawatt Laser were performed in the summers of 2011, 2012 and 2013. Numerical simulations of laser-plasma interactions were performed using Monte Carlo and Particle-in-Cell codes to design and support these experiments. Astrophysical applications of these results were also investigated.

  13. NuMI Low Energy Flux Prediction Release

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NuMI Low Energy Flux Prediction Release Neutrino Flux Predictions for the NuMI Beam hep-ex/1607.00704 Data Ancillary data files for this result are available on arXiv at http://arxiv.org/src/1607.00704/anc.< /li> Among the available data files are: pdf file describing format of all the available files root file of all the available fluxes python code to read and process MINERvA's flux predictions Text Files of the flux, uncertainties, and covariance matrix, with units of neutrinos/m^2/POT,

  14. Port Huron, MI Liquefied Natural Gas Exports (Million Cubic Feet)

    U.S. Energy Information Administration (EIA) Indexed Site

    (Million Cubic Feet) Port Huron, MI Liquefied Natural Gas Exports (Million Cubic Feet) Year Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2013 1 2014 1 1 1 1 2 1 1 1 1 1 2015 1 1 1 1 1 - = No Data Reported; -- = Not Applicable; NA = Not Available; W = Withheld to avoid disclosure of individual company data. Release Date: 08/31/2016 Next Release Date: 09/30/2016 Referring Pages: U.S. Liquefied Natural Gas Exports by Point of Exit Port Huron, MI LNG Exports to All Countries

  15. Next Generation Household Refrigerator

    Broader source: Energy.gov [DOE]

    Lead Performer: Oak Ridge National Laboratory - Oak Ridge, TN Partner: Whirlpool - Benton Harbor, MI

  16. Ground Motion Studies at NuMI

    SciTech Connect (OSTI)

    Mayda M. Velasco; Michal Szleper

    2012-02-20

    Ground motion can cause significant deterioration in the luminosity of a linear collider. Vibration of numerous focusing magnets causes continuous misalignments, which makes the beam emittance grow. For this reason, understanding the seismic vibration of all potential LC sites is essential and related efforts in many sites are ongoing. In this document we summarize the results from the studies specific to Fermilab grounds as requested by the LC project leader at FNAL, Shekhar Mishra in FY04-FY06. The Northwestern group focused on how the ground motion effects vary with depth. Knowledge of depth dependence of the seismic activity is needed in order to decide how deep the LC tunnel should be at sites like Fermilab. The measurements were made in the NuMI tunnel, see Figure 1. We take advantage of the fact that from the beginning to the end of the tunnel there is a height difference of about 350 ft and that there are about five different types of dolomite layers. The support received allowed to pay for three months of salary of Michal Szleper. During this period he worked a 100% of his time in this project. That include one week of preparation: 2.5 months of data taking and data analysis during the full period of the project in order to guarantee that we were recording high quality data. We extended our previous work and made more systematic measurements, which included detailed studies on stability of the vibration amplitudes at different depths over long periods of time. As a consequence, a better control and more efficient averaging out of the daytime variation effects were possible, and a better study of other time dependences before the actual depth dependence was obtained. Those initial measurements were made at the surface and are summarized in Figure 2. All measurements are made with equipment that we already had (two broadband seismometers KS200 from GEOTECH and DL-24 portable data recorder). The offline data analysis took advantage of the full Fourier spectra

  17. DOE - Office of Legacy Management -- Mitts-Merrel Co - MI 14

    Office of Legacy Management (LM)

    1993 MI.14-2 Site Operations: Reduced thorium metal chunks into particle sized pieces ... Primary Radioactive Materials Handled: Thorium MI.14-1 Radiological Survey(s): Yes - ...

  18. DOE - Office of Legacy Management -- Amex Specialty Metal Corp - MI 0-01

    Office of Legacy Management (LM)

    Amex Specialty Metal Corp - MI 0-01 FUSRAP Considered Sites Site: Amex Specialty Metal Corp (MI.0-01 ) Eliminated from further consideration under FUSRAP Designated Name: Not Designated Alternate Name: None Location: Coldwater , Michigan MI.0-01-1 Evaluation Year: 1987 MI.0-01-1 Site Operations: No indication that AMEX performed work for MED or AEC activities. Originally included on FUSRAP list due to fact that AMEX purchased milling equipment from a company that had done uranium milling.

  19. MiR-125a TNF receptor-associated factor 6 to inhibit osteoclastogenesis

    SciTech Connect (OSTI)

    Guo, Li-Juan; Liao, Lan; Yang, Li; Li, Yu; Jiang, Tie-Jian

    2014-02-15

    MicroRNAs (miRNAs) play important roles in osteoclastogenesis and bone resorption. In the present study, we found that miR-125a was dramatically down-regulated during macrophage colony stimulating factor (M-CSF) and receptor activator of nuclear factor-κB ligand (RANKL) induced osteoclastogenesis of circulating CD14+ peripheral blood mononuclear cells (PBMCs). Overexpression of miR-125a in CD14+ PBMCs inhibited osteoclastogenesis, while inhibition of miR-125a promoted osteoclastogenesis. TNF receptor-associated factor 6 (TRAF6), a transduction factor for RANKL/RANK/NFATc1 signal, was confirmed to be a target of miR-125a. EMSA and ChIP assays confirmed that NFATc1 bound to the promoter of the miR-125a. Overexpression of NFATc1 inhibited miR-125a transcription, and block of NFATc1 expression attenuated RANKL-regulated miR-125a transcription. Here, we reported that miR-125a played a biological function in osteoclastogenesis through a novel TRAF6/ NFATc1/miR-125a regulatory feedback loop. It suggests that regulation of miR-125a expression may be a potential strategy for ameliorating metabolic disease. - Highlights: • MiR-125a was significantly down-regulated in osteoclastogenesis of CD14+ PBMCs. • MiR-125a inhibited osteoclast differentiation by targeting TRAF6. • NFATc1 inhibited miR-125a transciption by binding to the promoter of miR-125a. • TRAF6/NFATc1 and miR-125a form a regulatory feedback loop in osteoclastogenesis.

  20. MiR-145 functions as a tumor suppressor targeting NUAK1 in human intrahepatic cholangiocarcinoma

    SciTech Connect (OSTI)

    Xiong, Xinkui; Sun, Daoyi; Chai, Hao; Shan, Wengang; Yu, Yue; Pu, Liyong; Cheng, Feng

    2015-09-18

    The dysregulation of micro (mi)RNAs is associated with cancer development. The miRNA miR-145 is downregulated in intrahepatic cholangiocarcinoma (ICC); however, its precise role in tumor progression has not yet been elucidated. Novel (nua) kinase family (NUAK)1 functions as an oncogene in various cancers and is a putative target of miR-145 regulation. In this study, we investigated the regulation of NUAK1 by miR-145 in ICC. We found that miR-145 level was significantly decreased in ICC tissue and cell lines, which corresponded with an increase in NUAK1 expression. NUAK1 was found to be a direct target of miR-145 regulation. The overexpression of miR-145 in ICC cell lines inhibited proliferation, growth, and invasion by suppressing NUAK1 expression, which was associated with a decrease in Akt signaling and matrix metalloproteinase protein expression. Similar results were observed by inhibiting NUAK1 expression. These results demonstrate that miR-145 can prevent ICC progression by targeting NUAK1 and its downstream effectors, and can therefore be useful for clinical diagnosis and targeted therapy of ICC. - Highlights: • MiR-145 suppresses ICC proliferation and invasion abilities. • We demonstrated that miR-145 directly targets NUAK1 in ICC. • MiR-145 expression in ICC was associated with Akt signaling and MMPs expression.

  1. Neutron scattering study of spin ordering and stripe pinning in superconducting <mi>La>1.93<mi>Sr>0.07<mi>CuO>4

    SciTech Connect (OSTI)

    Jacobsen, H.; Zaliznyak, I. A.; Savici, A. T.; Winn, B. L.; Chang, S.; Hücker, M.; Gu, G. D.; Tranquada, J. M.

    2015-11-20

    The relationships among charge order, spin fluctuations, and superconductivity in underdoped cuprates remain controversial. We use neutron scattering techniques to study these phenomena in <mi>La>1.93<mi>Sr>0.07<mi>CuO>4 a superconductor with a transition temperature of Tc = 20 K. At T<< Tc, we find incommensurate spin fluctuations with a quasielastic energy spectrum and no sign of a gap within the energy range from 0.2 to 15 meV. A weak elastic magnetic component grows below ~ 10 K, consistent with results from local probes. Regarding the atomic lattice, we have discovered unexpectedly strong fluctuations of the CuO6 octahedra about Cu-O bonds, which are associated with inequivalent O sites within the CuO2 planes. Moreover, we observed a weak elastic (3 30) superlattice peak that implies a reduced lattice symmetry. The presence of inequivalent O sites rationalizes various pieces of evidence for charge stripe order in underdoped La2-xSrxCuO4. The coexistence of superconductivity with quasi-static spin-stripe order suggests the presence of intertwined orders; however, the rotation of the stripe orientation away from the Cu-O bonds might be connected with evidence for a finite gap at the nodal points of the superconducting gap function.

  2. Radiosensitizing Effects of Ectopic miR-101 on Non-Small-Cell Lung Cancer Cells Depend on the Endogenous miR-101 Level

    SciTech Connect (OSTI)

    Chen, Susie; Wang Hongyan; Ng, Wooi Loon; Curran, Walter J.; Wang Ya

    2011-12-01

    Purpose: Previously, we showed that ectopic miR-101 could sensitize human tumor cells to radiation by targeting ATM and DNA-PK catalytic subunit (DNA-PKcs) to inhibit DNA repair, as the endogenous miR-101 levels are low in tumors in general. However, the heterogeneity of human cancers may result in an exception. The purpose of this study was to test the hypothesis that a few tumor cell lines with a high level of endogenous miR-101 would prove less response to ectopic miR-101. Methods and Materials: Fourteeen non-small-cell lung cancer (NSCLC) cell lines and one immortalized non-malignant lung epithelial cell line (NL20) were used for comparing endogenous miR-101 levels by real-time reverse transcription-polymerase chain reaction. Based on the different miR-101 levels, four cell lines with different miR-101 levels were chosen for transfection with a green fluorescent protein-lentiviral plasmid encoding miR-101. The target protein levels were measured by using Western blotting. The radiosensitizing effects of ectopic miR-101 on these NSCLC cell lines were determined by a clonogenic assay and xenograft mouse model. Results: The endogenous miR-101 level was similar or lower in 13 NSCLC cell lines but was 11-fold higher in one cell line (H157) than in NL20 cells. Although ectopic miR-101 efficiently decreased the ATM and DNA-PKcs levels and increased the radiosensitization level in H1299, H1975, and A549 cells, it did not change the levels of the miR-101 targets or radiosensitivity in H157 cells. Similar results were observed in xenograft mice. Conclusions: A small number of NSCLC cell lines could have a high level of endogenous miR-101. The ectopic miR-101 was able to radiosensitize most NSCLC cells, except for the NSCLC cell lines that had a much higher endogenous miR-101 level. These results suggest that when we choose one miRNA as a therapeutic tool, the endogenous level of the miRNA in each tumor should be considered.

  3. Analysis of natural gases, AL, AR, FL, GA, IL, IN, IA, KY, LA, MD, MI, MS, MO, NJ, NY, NC, OH, PA, TN, VA, and WV; 1951-1991 (for microcomputers). Data file

    SciTech Connect (OSTI)

    Not Available

    1991-01-01

    The U.S. Bureau of Mines diskette contains analysis and related source data for 2,357 natural gas samples collected from miscellaneous states, which include the following states: Alabama, Arkansas (except Arkoma Basin), Florida, Georgia, Illinois, Indiana, Iowa, Kentucky, Louisiana, Maryland, Michigan, Mississippi, Missouri, New Jersey, New York, North Carolina, Ohio, Pennsylvania, Tennessee, Virginia, and West Virginia. All samples were obtained and analyzed as part of the Bureau's investigations of occurrences of helium in natural gases of countries with free market economies. The survey has been conducted since 1917. The analysis contained on the diskette contain the full range of component analysis data. Five files are on the diskette: READ.ME, MISC.TXT, MISC.DBF, USHEANAL.DBF, and BASINCDE.TXT.

  4. EngenuitySC Commercialization and Entrepreneurial Training Project

    SciTech Connect (OSTI)

    Hughes, Meghan; Hutton, Katherine R

    2012-12-31

    A team led by EngenuitySC has performed education and outreach on development of advanced energy markets that will enable wider use of clean energy technologies. This report details the efforts that have made significant advances to improve the market place through education, outreach, and increased communications between industry members. The project resulted in two self-funded industry clusters known as the Fuel Cell Collaborative and NuHub. This project has focused on building and strengthening the leading clean energy clusters in South Carolina: nuclear energy and fuel cell technologies. For the nuclear industry, a new cluster was developed that is now known as NuHub. This cluster has already engaged over 25 nuclear industry leaders or suppliers, four public sector partners, six community economic development foundations, and nearly ten academic partners in a 175 mile radius between Augusta, Georgia and Charlotte, North Carolina. Our outreach has touched over 2,000 stakeholders through the website alone, not including the public audiences and members of the business community reached through news stories and releases that were distributed to over 620 print and online publications. NuHub has established a formal leadership structure, developed subcommittees to focus on industry issues, instituted educational programs for the workforce, and created an industry funding structure that will sustain the industry cluster and mission. NuHub has participated in a wide-variety of community building and outreach activities since its formation under this grant. In the two years since its creation in 2010, we have initiated efforts focused in four main areas that correlate with the four NuHub subcommittees including: innovation, workforce development, industry engagement, and marketing and communications. NuHub successfully raised over $160,000 in both public and private funding, which has supported work to grow the cluster and engage partners including NuScale, Fluor, and

  5. Talk to the Magellan Staff at SC10 in New Orleans

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Talk to the Magellan Staff at SC10 in New Orleans Talk to the Magellan Staff at SC10 in New Orleans October 12, 2010 Magellan will be highlighted at a variety of workshops and talks at SC10. The Petascale Data Analytics on Clouds Workshop will include talks by Kathy Yelick, Shane Canon, and Nick Wright. On Wednesday, there will be a joint presentation with a collaborators at Argonne in the Argonne booth. That presentation will be followed by a talk in the Berkeley Lab booth (#2448) along with

  6. DOE Zero Energy Ready Home Case Study: Amerisips Homes, Charleston, SC |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Case Study: Amerisips Homes, Charleston, SC DOE Zero Energy Ready Home Case Study: Amerisips Homes, Charleston, SC Case study of a DOE Zero Energy Ready home on Johns Island in Charleston, SC, that scored HERS 30 without PV, or HERS 1 with 6-kW of PV. This custom 2-story, 2,085 ft2, home is constructed of structural insulated panels, with 6.5-in. SIPs in the walls and 8.25-in. SIPs in the floor and roof. The HVAC system includes an air-to-water heat pump with fan coil

  7. Office of Science | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    SC Watch List Report Template .pdf file (172KB), October 2010 ASCR Facilities Management Plan .pdf file (155KB) Management of U.S. ITER Project .pdf file (402KB), December 4, 2012 ...

  8. New York Regions | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    York Regions National Science Bowl (NSB) NSB Home About High School High School Students ... WDTS Home Contact Information National Science Bowl U.S. Department of Energy SC-27 ...

  9. New York Regions | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    York Regions National Science Bowl (NSB) NSB Home About High School Middle School Middle ... WDTS Home Contact Information National Science Bowl U.S. Department of Energy SC-27 ...

  10. Solarcoating Machinery GmbH ScM | Open Energy Information

    Open Energy Info (EERE)

    Name: Solarcoating Machinery GmbH (ScM) Place: Dormagen, Germany Zip: 41539 Product: German manufacturer of turnkey thin-film fab including the cleaning, TCO and PECVD systems....

  11. PM Update - Steve Meador, Acting Dir for Proj Assessment-SC,...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Update - Steve Meador, Acting Dir for Proj Assessment-SC, Jack Surash, Dep Asst Secretary for APM-EM, Bob Raines, Assoc. Administrator for APM-NNSA PM Update - Steve Meador, Acting...

  12. DOE/SC-ARM-15-027 Radon Measurements of Atmospheric Mixing

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of Atmospheric Mixing (RAMIX) 2006-2014 Final Campaign Summary ML Fischer SC Biraud A Hirsch May 2015 DISCLAIMER This report was prepared as an account of work sponsored by the...

  13. Synthesis of the novel perovskite-type oxyfluoride PbScO{sub...

    Office of Scientific and Technical Information (OSTI)

    PbScOsub 2F has a cubic perovskite-type structure with Pb ions displaced from the ideal A-site positions along the <110> direction. By thermal gravity and differential thermal ...

  14. Early Career Research Program Homepage | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Brochures, Logos, & Information Resources About About Home Organization Budget Field Operations Federal Advisory Committees History Scientific and Technical Information Honors & Awards Jobs Brochures, Logos, & Information Resources Brochures Fact Sheets SC Logos Newsletters Connect with SC Contact Contact Information Office of Science U.S. Department of Energy 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5430 Brochures, Logos, & Information Resources Print Text

  15. Valerie R. Diggs | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Valerie R. Diggs Deputy Director for Science Programs Deputy Director Home Mission & Functions Deputy Director Biography Organization Staff Presentations & Testimony Federal Advisory Committees Committees of Visitors Contact Information Deputy Director for Science Programs U.S. Department of Energy SC-2/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5430 F: (202) 586-4120 E: Email Us U.S. Department of Energy SC-2/Germantown Building 1000 Independence

  16. Presentations & Testimony | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Presentations & Testimony Deputy Director for Science Programs Deputy Director Home Mission & Functions Deputy Director Biography Organization Staff Presentations & Testimony Archives Federal Advisory Committees Committees of Visitors Contact Information Deputy Director for Science Programs U.S. Department of Energy SC-2/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5430 F: (202) 586-4120 E: Email Us U.S. Department of Energy SC-2/Germantown Building

  17. Dr. Benjamin L. Brown | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Benjamin L. Brown Deputy Director for Science Programs Deputy Director Home Mission & Functions Deputy Director Biography Organization Staff Presentations & Testimony Federal Advisory Committees Committees of Visitors Contact Information Deputy Director for Science Programs U.S. Department of Energy SC-2/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5430 F: (202) 586-4120 E: Email Us U.S. Department of Energy SC-2/Germantown Building 1000 Independence

  18. Dr. Corey Cohn | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Dr. Corey Cohn Deputy Director for Science Programs Deputy Director Home Mission & Functions Deputy Director Biography Organization Staff Presentations & Testimony Federal Advisory Committees Committees of Visitors Contact Information Deputy Director for Science Programs U.S. Department of Energy SC-2/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5430 F: (202) 586-4120 E: Email Us U.S. Department of Energy SC-2/Germantown Building 1000 Independence Ave.,

  19. Dr. Julie A. Carruthers | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Dr. Julie A. Carruthers Deputy Director for Science Programs Deputy Director Home Mission & Functions Deputy Director Biography Organization Staff Presentations & Testimony Federal Advisory Committees Committees of Visitors Contact Information Deputy Director for Science Programs U.S. Department of Energy SC-2/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5430 F: (202) 586-4120 E: Email Us U.S. Department of Energy SC-2/Germantown Building 1000

  20. Dr. Laura Biven | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Dr. Laura Biven Deputy Director for Science Programs Deputy Director Home Mission & Functions Deputy Director Biography Organization Staff Presentations & Testimony Federal Advisory Committees Committees of Visitors Contact Information Deputy Director for Science Programs U.S. Department of Energy SC-2/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5430 F: (202) 586-4120 E: Email Us U.S. Department of Energy SC-2/Germantown Building 1000 Independence

  1. Dr. Linda G. Blevins | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Dr. Linda G. Blevins Deputy Director for Science Programs Deputy Director Home Mission & Functions Deputy Director Biography Organization Staff Presentations & Testimony Federal Advisory Committees Committees of Visitors Contact Information Deputy Director for Science Programs U.S. Department of Energy SC-2/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5430 F: (202) 586-4120 E: Email Us U.S. Department of Energy SC-2/Germantown Building 1000 Independence

  2. Dr. Patrick Glynn | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Dr. Patrick Glynn Deputy Director for Science Programs Deputy Director Home Mission & Functions Deputy Director Biography Organization Staff Presentations & Testimony Federal Advisory Committees Committees of Visitors Contact Information Deputy Director for Science Programs U.S. Department of Energy SC-2/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5430 F: (202) 586-4120 E: Email Us U.S. Department of Energy SC-2/Germantown Building 1000 Independence

  3. Four ALCF Papers Accepted to SC13 Technical Papers Program | Argonne

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Leadership Computing Facility Four ALCF Papers Accepted to SC13 Technical Papers Program Author: ALCF staff July 18, 2013 Facebook Twitter LinkedIn Google E-mail Printer-friendly version Four papers from the Argonne Leadership Computing Facility have been selected for the Technical Papers Program at SC13, the premier annual international supercomputing conference, and the leading venue for presenting high-quality original research in high-performance computing, networking, storage, and

  4. Elizabeth O'Malley | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Elizabeth O'Malley Deputy Director for Science Programs Deputy Director Home Mission & Functions Deputy Director Biography Organization Staff Presentations & Testimony Federal Advisory Committees Committees of Visitors Contact Information Deputy Director for Science Programs U.S. Department of Energy SC-2/Forrestal Building 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5430 F: (202) 586-4120 E: Email Us U.S. Department of Energy SC-2/Germantown Building 1000 Independence

  5. Inspiring Girls to Explore STEM Careers in Charleston, SC | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Inspiring Girls to Explore STEM Careers in Charleston, SC Inspiring Girls to Explore STEM Careers in Charleston, SC July 29, 2014 - 9:05am Addthis Female engineers from SSC Atlantic and local industry partners shared their backgrounds, explained their work, and encouraged the girls to think about STEM careers at the Girls Day Out event in Charleston, South Carolina. Female engineers from SSC Atlantic and local industry partners shared their backgrounds, explained their work, and

  6. ESPC Workshop (Nashville, TN)

    Broader source: Energy.gov [DOE]

    This three-day workshop educates attendees on how to implement energy and water projects through an energy savings performance contract (ESPC).

  7. NETL F 451.1/1-1, Categorical Exclusion Designation Form

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    M616003376 Argonne National Lab Lemont, IL Cummins, Columbus, IN; University of Michigan, Ann Arbor, MI; Ohio State University, Columbus, OH; Purdue University, West Lafayette, IN; Oak Ridge National Laboratory, Oak Ridge, TN; Freightliner, Gaffney, SC EE/TDIC/ETD/EERE Team John Jason Conley U.S.- China Clean Energy Research Consortium (CERC) Medium and Heavy Duty Trucks The project will focus on the development and demonstration of medium and heavy duty truck technologies to improve efficiency.

  8. Categorical Exclusion (CX) Determinations | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Categorical Exclusion (CX) Determinations Oak Ridge National Laboratory Site Office (OSO) OSO Home About Projects Contract Management NEPA Documents Categorical Exclusion Determinations Environmental Assessments and Environmental Impact Statements Contact Information Oak Ridge National Laboratory Site Office U.S. Department of Energy Post Office Box 2008 Oak Ridge, TN 37831-6269 P: (865) 576-0710 National Environmental Policy Act (NEPA) Documents Categorical Exclusion (CX) Determinations Print

  9. Real Property Management | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Real Property Management Integrated Support Center (ISC) ISC Home About Services Freedom of Information Act (FOIA) Privacy Act NEPA Documents Contact Information Integrated Support Center Roxanne Purucker U.S. Department of Energy 9800 S. Cass Avenue Argonne, IL 60439 P: (630) 252-2110 Kenneth Tarcza U.S. Department of Energy 200 Administration Road Oak Ridge, TN 37830 P: (865) 576-4444 Services Real Property Management Print Text Size: A A A FeedbackShare Page Real Property Management provides

  10. Contractor Human Resources | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Contractor Human Resources Integrated Support Center (ISC) ISC Home About Services Freedom of Information Act (FOIA) Privacy Act NEPA Documents Contact Information Integrated Support Center Roxanne Purucker U.S. Department of Energy 9800 S. Cass Avenue Argonne, IL 60439 P: (630) 252-2110 Kenneth Tarcza U.S. Department of Energy 200 Administration Road Oak Ridge, TN 37830 P: (865) 576-4444 Services Contractor Human Resources Print Text Size: A A A FeedbackShare Page Contractor Human Resources

  11. DLEU2, frequently deleted in malignancy, functions as a critical host gene of the cell cycle inhibitory microRNAs miR-15a and miR-16-1

    SciTech Connect (OSTI)

    Lerner, Mikael; Harada, Masako; Loven, Jakob; Castro, Juan; Davis, Zadie; Oscier, David; Henriksson, Marie; Sangfelt, Olle; Grander, Dan; Corcoran, Martin M.

    2009-10-15

    The microRNAs miR-15a and miR-16-1 are downregulated in multiple tumor types and are frequently deleted in chronic lymphocytic leukemia (CLL), myeloma and mantle cell lymphoma. Despite their abundance in most cells the transcriptional regulation of miR-15a/16-1 remains unclear. Here we demonstrate that the putative tumor suppressor DLEU2 acts as a host gene of these microRNAs. Mature miR-15a/miR-16-1 are produced in a Drosha-dependent process from DLEU2 and binding of the Myc oncoprotein to two alterative DLEU2 promoters represses both the host gene transcript and levels of mature miR-15a/miR-16-1. In line with a functional role for DLEU2 in the expression of the microRNAs, the miR-15a/miR-16-1 locus is retained in four CLL cases that delete both promoters of this gene and expression analysis indicates that this leads to functional loss of mature miR-15a/16-1. We additionally show that DLEU2 negatively regulates the G1 Cyclins E1 and D1 through miR-15a/miR-16-1 and provide evidence that these oncoproteins are subject to miR-15a/miR-16-1-mediated repression under normal conditions. We also demonstrate that DLEU2 overexpression blocks cellular proliferation and inhibits the colony-forming ability of tumor cell lines in a miR-15a/miR-16-1-dependent way. Together the data illuminate how inactivation of DLEU2 promotes cell proliferation and tumor progression through functional loss of miR-15a/miR-16-1.

  12. Genome-Wide Analysis of miRNA targets in Brachypodium and Biomass Energy Crops

    SciTech Connect (OSTI)

    Green, Pamela J.

    2015-08-11

    MicroRNAs (miRNAs) contribute to the control of numerous biological processes through the regulation of specific target mRNAs. Although the identities of these targets are essential to elucidate miRNA function, the targets are much more difficult to identify than the small RNAs themselves. Before this work, we pioneered the genome-wide identification of the targets of Arabidopsis miRNAs using an approach called PARE (German et al., Nature Biotech. 2008; Nature Protocols, 2009). Under this project, we applied PARE to Brachypodium distachyon (Brachypodium), a model plant in the Poaceae family, which includes the major food grain and bioenergy crops. Through in-depth global analysis and examination of specific examples, this research greatly expanded our knowledge of miRNAs and target RNAs of Brachypodium. New regulation in response to environmental stress or tissue type was found, and many new miRNAs were discovered. More than 260 targets of new and known miRNAs with PARE sequences at the precise sites of miRNA-guided cleavage were identified and characterized. Combining PARE data with the small RNA data also identified the miRNAs responsible for initiating approximately 500 phased loci, including one of the novel miRNAs. PARE analysis also revealed that differentially expressed miRNAs in the same family guide specific target RNA cleavage in a correspondingly tissue-preferential manner. The project included generation of small RNA and PARE resources for bioenergy crops, to facilitate ongoing discovery of conserved miRNA-target RNA regulation. By associating specific miRNA-target RNA pairs with known physiological functions, the research provides insights about gene regulation in different tissues and in response to environmental stress. This, and release of new PARE and small RNA data sets should contribute basic knowledge to enhance breeding and may suggest new strategies for improvement of biomass energy crops.

  13. miR-4295 promotes cell proliferation and invasion in anaplastic thyroid carcinoma via CDKN1A

    SciTech Connect (OSTI)

    Shao, Mingchen; Geng, Yiwei; Lu, Peng; Xi, Ying; Wei, Sidong; Wang, Liuxing; Fan, Qingxia; Ma, Wang

    2015-09-04

    MicroRNAs (miRNAs) play important roles in the pathogenesis of many types of cancers by negatively regulating gene expression at posttranscriptional level. However, the role of microRNAs in anaplastic thyroid carcinoma (ATC), has remained elusive. Here, we identified that miR-4295 promotes ATC cell proliferation by negatively regulates its target gene CDKN1A. In ATC cell lines, CCK-8 proliferation assay indicated that the cell proliferation was promoted by miR-4295, while miR-4295 inhibitor significantly inhibited the cell proliferation. Transwell assay showed that miR-4295 mimics significantly promoted the migration and invasion of ATC cells, whereas miR-4295 inhibitors significantly reduced cell migration and invasion. luciferase assays confirmed that miR-4295 directly bound to the 3'untranslated region of CDKN1A, and western blotting showed that miR-4295 suppressed the expression of CDKN1A at the protein levels. This study indicated that miR-4295 negatively regulates CDKN1A and promotes proliferation and invasion of ATC cell lines. Thus, miR-4295 may represent a potential therapeutic target for ATC intervention. - Highlights: • miR-4295 mimics promote the proliferation and invasion of ATC cells. • miR-4295 inhibitors inhibit the proliferation and invasion of ATC cells. • miR-4295 targets 3′UTR of CDKN1A in ATC cells. • miR-4295 negatively regulates CDKN1A in ATC cells.

  14. Microfluidic Molecular Assay Platform for the Detection of miRNAs...

    Office of Scientific and Technical Information (OSTI)

    Article: Microfluidic Molecular Assay Platform for the Detection of miRNAs, mRNAs, Proteins, and Post-translational Modifications at Single-cell Resolution. Citation Details...

  15. Groundwater protection for the NuMI project

    SciTech Connect (OSTI)

    Wehmann, A.; Smart, W.; Menary, S.; Hylen, J.; Childress, S.

    1997-10-01

    The physics requirements for the long base line neutrino oscillation experiment MINOS dictate that the NuMI beamline be located in the aquifer at Fermilab. A methodology is described for calculating the level of radioactivation of groundwater caused by operation of this beamline. A conceptual shielding design for the 750 meter long decay pipe is investigated which would reduce radioactivation of the groundwater to below government standards. More economical shielding designs to meet these requirements are being explored. Also, information on local geology, hydrogeology, government standards, and a glossary have been included.

  16. Enhanced hardness in epitaxial TiAlScN alloy thin films and rocksalt TiN/(Al,Sc)N superlattices

    SciTech Connect (OSTI)

    Saha, Bivas; Lawrence, Samantha K.; Bahr, David F.; Schroeder, Jeremy L.; Birch, Jens; Sands, Timothy D.

    2014-10-13

    High hardness TiAlN alloys for wear-resistant coatings exhibit limited lifetimes at elevated temperatures due to a cubic-AlN to hexagonal-AlN phase transformation that leads to decreasing hardness. We enhance the hardness (up to 46 GPa) and maximum operating temperature (up to 1050 °C) of TiAlN-based coatings by alloying with scandium nitride to form both an epitaxial TiAlScN alloy film and epitaxial rocksalt TiN/(Al,Sc)N superlattices on MgO substrates. The superlattice hardness increases with decreasing period thickness, which is understood by the Orowan bowing mechanism of the confined layer slip model. These results make them worthy of additional research for industrial coating applications.

  17. Bixbyite- and anatase-type phases in the system Sc-Ta-O-N

    SciTech Connect (OSTI)

    Stork, A.; Schilling, H.; Wessel, C.; Wolff, H.; Boerger, A.; Baehtz, C.; Becker, K.-D.; Dronskowski, R.; Lerch, M.

    2010-09-15

    The aim of our study was to modify the basis compound ss-TaON, which crystallizes in the monoclinic baddeleyite-type, by incorporation of appropriate dopant ions, in order to obtain anion-deficient cubic fluorite-type phases, which are of interest as solids with mobile nitrogen ions. For this purpose, scandium-doped tantalum oxide nitrides were prepared by ammonolysis of amorphous oxide precursors. An unexpected variety of phases with different structural features was observed: bixbyite-type phases of general composition Sc{sub x}Ta{sub 1-x}(O,N){sub y} with 0.33{<=}x{<=}1 and 1.7{<=}y{<=}1.9, yellow colored metastable anatase-type phases such as Sc{sub 0.1}Ta{sub 0.9}O{sub 1.2}N{sub 0.8} or Sc{sub 0.15}Ta{sub 0.85}O{sub 1.3}N{sub 0.7} and, additionally, anosovite-type phases Sc{sub x}Ta{sub 3-x}O{sub 2x}N{sub 5-2x} with 0{<=}x{<=}1.05. Selected phases were investigated by UV/vis spectroscopy. Anatase- and anosovite-type compounds show brilliant colors. In the anatase-type phase, a possible anion ordering was examined by theoretical methods. Additionally, energy calculations on phase stability were performed for Sc{sub x}Ta{sub 1-x}O{sub 1+2x}N{sub 1-2x} in the baddeleyite, rutile, and anatase structure types with varying amounts of dopants. - Graphical abstract: New anatase- and bixbyite-type phases obtained as single-phase samples in the system Sc-Ta-O-N.

  18. miR-129 suppresses tumor cell growth and invasion by targeting PAK5 in hepatocellular carcinoma

    SciTech Connect (OSTI)

    Zhai, Jian; Qu, Shuping; Li, Xiaowei; Zhong, Jiaming; Chen, Xiaoxia; Qu, Zengqiang; Wu, Dong

    2015-08-14

    Emerging evidence suggests that microRNAs (miRNAs) play important roles in regulating HCC development and progression; however, the mechanisms by which their specific functions and mechanisms remained to be further explored. miR-129 has been reported in gastric cancers, lung cancer and colon cancer. In this study, we disclosed a new tumor suppresser function of miR-129 in HCC. We also found the downregulation of miR-129 occurred in nearly 3/4 of the tumors examined (56/76) compared with adjacent nontumorous tissues, which was more importantly, correlated to the advanced stage and vascular invasion. We then demonstrated that miR-129 overexpression attenuated HCC cells proliferation and invasion, inducing apoptosis in vitro. Moreover, we used miR-129 antagonist and found that anti-miR-129 promoted HCC cells malignant phenotypes. Mechanistically, our further investigations revealed that miR-129 suppressed cell proliferation and invasion by targeting the 3’-untranslated region of PAK5, as well as miR-129 silencing up-regulated PAK5 expression. Moreover, miR-129 expression was inversely correlated with PAK5 expression in 76 cases of HCC samples. RNA interference of PAK5 attenuated anti-miR-129 mediated cell proliferation and invasion in HCC cells. Taken together, these results demonstrated that miR-129 suppressed tumorigenesis and progression by directly targeting PAK5, defining miR-129 as a potential treatment target for HCC. - Highlights: • Decreased of miR-129 is found in HCC and associated with advanced stage and metastasis. • miR-129 suppresses proliferation and invasion of HCC cells. • miR-129 directly targets the 3′ UTR of PAK5 and diminishes PAK5 expression. • PAK5 is involved in miR-129 mediated suppression functions.

  19. MiR-153 inhibits migration and invasion of human non-small-cell lung cancer by targeting ADAM19

    SciTech Connect (OSTI)

    Shan, Nianxi; Shen, Liangfang; Wang, Jun; He, Dan; Duan, Chaojun

    2015-01-02

    Highlights: • Decreased miR-153 and up-regulated ADAM19 are correlated with NSCLC pathology. • MiR-153 inhibits the proliferation and migration and invasion of NSCLC cells in vitro. • ADAM19 is a direct target of miR-153. • ADAM19 is involved in miR-153-suppressed migration and invasion of NSCLC cells. - Abstract: MiR-153 was reported to be dysregulated in some human cancers. However, the function and mechanism of miR-153 in lung cancer cells remains unknown. In this study, we investigated the role of miR-153 in human non-small-cell lung cancer (NSCLC). Using qRT-PCR, we demonstrated that miR-153 was significantly decreased in clinical NSCLC tissues and cell lines, and downregulation of miR-153 was significantly correlated with lymph node status. We further found that ectopic expression of miR-153 significantly inhibited the proliferation and migration and invasion of NSCLC cells in vitro, suggesting that miR-153 may be a novel tumor suppressor in NSCLC. Further integrated analysis revealed that ADAM19 is as a direct and functional target of miR-153. Luciferase reporter assay demonstrated that miR-153 directly targeted 3′UTR of ADAM19, and correlation analysis revealed an inverse correlation between miR-153 and ADAM19 mRNA levels in clinical NSCLC tissues. Knockdown of ADAM19 inhibited migration and invasion of NSCLC cells which was similar with effects of overexpression of miR-153, while overexpression of ADAM19 attenuated the function of miR-153 in NSCLC cells. Taken together, our results highlight the significance of miR-153 and ADAM19 in the development and progression of NSCLC.

  20. Transcriptional regulation of miR-146b by C/EBPβ LAP2 in esophageal cancer cells

    SciTech Connect (OSTI)

    Li, Junxia; Shan, Fabo; Xiong, Gang; Wang, Ju-Ming; Wang, Wen-Lin; Xu, Xueqing; Bai, Yun

    2014-03-28

    Highlights: • MiR-146b promotes esophageal cancer cell proliferation. • MiR-146b inhibits esophageal cancer cell apoptosis. • C/EBPβ directly binds to miR-146b promoter conserved region. • MiR-146b is up-regulated by C/EBPβ LAP2 transcriptional activation. - Abstract: Recent clinical study indicated that up-regulation of miR-146b was associated with poor overall survival of patients in esophageal squamous cell carcinoma. However, the underlying mechanism of miR-146b dysregulation remains to be explored. Here we report that miR-146b promotes cell proliferation and inhibits cell apoptosis in esophageal cancer cell lines. Mechanismly, two C/EBPβ binding motifs are located in the miR-146b promoter conserved region. Among the three isoforms of C/EBPβ, C/EBPβ LAP2 positively regulated miR-146b expression and increases miR-146b levels in a dose-dependent manner through transcription activation of miR-146b gene. Together, these results suggest a miR-146b regulatory mechanism involving C/EBPβ, which may contribute to the up-regulation of miR-146b in esophageal squamous cell carcinoma.

  1. miR-30a suppresses breast cancer cell proliferation and migration by targeting Eya2

    SciTech Connect (OSTI)

    Fu, Jing; Xu, Xiaojie; Kang, Lei; Zhou, Liying; Wang, Shibin; Lu, Juming; Cheng, Long; Fan, Zhongyi; Yuan, Bin; Tian, Peirong; Zheng, Xiaofei; Yu, Chengze; Ye, Qinong; Lv, Zhaohui

    2014-03-07

    Highlights: • miR-30a represses Eya2 expression by binding to the 3′-untranslated region of Eya2. • The miR-30a/EYA2 axis regulates breast cancer cell proliferation and migration. • The miR-30a/EYA2 axis modulates G1/S cell cycle progression. • The miR-30a/EYA2 axis is dysregulated in breast cancer patients. - Abstract: Eye absent (Eya) proteins are involved in cell fate determination in a broad spectrum of cells and tissues. Aberrant expression of Eya2 has been documented in a variety of cancers and correlates with clinical outcome. However, whether microRNAs (miRNAs) can regulate Eya2 expression remains unknown. Here, we show that miR-30a represses Eya2 expression by binding to the 3′-untranslated region of Eya2. Overexpression of Eya2 in miR-30a-transfected breast cancer cells effectively rescued the inhibition of cell proliferation and migration caused by miR-30a. Knockdown of Eya2 by small-interfering RNA (siRNA) in breast cancer cells mimicked the effect induced by miR-30a and abolished the ability of miR-30a to regulate breast cancer cell proliferation and migration. The miR-30a/Eya2 axis could regulate G1/S cell cycle progression, accompanied by the modulation of expression of cell cycle-related proteins, including cyclin A, cyclin D1, cyclin E, and c-Myc. Moreover, miR-30a expression was downregulated in breast cancer patients, and negatively correlated with Eya2, which was upregulated in breast cancer patients. These data suggest that the miR-30a/Eya2 axis may play an important role in breast cancer development and progression and that miR-30a activation or Eya2 inhibition may be a useful strategy for cancer treatment.

  2. miR-92a is upregulated in cervical cancer and promotes cell proliferation and invasion by targeting FBXW7

    SciTech Connect (OSTI)

    Zhou, Chuanyi; Shen, Liangfang; Mao, Lei; Wang, Bing; Li, Yang; Yu, Huizhi

    2015-02-27

    MicroRNAs (miRNAs) are involved in the cervical carcinogenesis and progression. In this study, we investigated the role of miR-92a in progression and invasion of cervical cancer. MiR-92a was significantly upregulated in cervical cancer tissues and cell lines. Overexpression of miR-92a led to remarkably enhanced proliferation by promoting cell cycle transition from G1 to S phase and significantly enhanced invasion of cervical cancer cells, while its knockdown significantly reversed these cellular events. Bioinformatics analysis suggested F-box and WD repeat domain-containing 7 (FBXW7) as a novel target of miR-92a, and miR-92a suppressed the expression level of FBXW7 mRNA by direct binding to its 3′-untranslated region (3′UTR). Expression of miR-92a was negatively correlated with FBXW7 in cervical cancer tissues. Furthermore, Silencing of FBXW7 counteracted the effects of miR-92a suppression, while its overexpression reversed oncogenic effects of miR-92a. Together, these findings indicate that miR-92a acts as an onco-miRNA and may contribute to the progression and invasion of cervical cancer, suggesting miR-92a as a potential novel diagnostic and therapeutic target of cervical cancer. - Highlights: • miR-92a is elevated in cervical cancer tissues and cell lines. • miR-92a promotes cervical cancer cell proliferation, cell cycle transition from G1 to S phase and invasion. • FBXW7 is a direct target of miR-92a. • FBXW7 counteracts the oncogenic effects of miR-92a on cervical cancer cells.

  3. DOE Zero Energy Ready Home Case Study: Amerisips Homes, Charleston, SC

    Broader source: Energy.gov [DOE]

    Case study of a DOE Zero Energy Ready home on Johns Island in Charleston, SC, that scored HERS 30 without PV, or HERS 1 with 6-kW of PV. This custom 2-story, 2,085 ft2, home is constructed of...

  4. Final Report for Research supported by US DoE grant DE-SC0006721

    SciTech Connect (OSTI)

    Brizard, Alain J.

    2014-08-27

    A final report is presented on research carried out by Alain J. Brizard (Principal Investigator) with funding provided by the U.S. DoE grant No. DE-SC0006721 during the period of 08/01/2011 to 07/31/2014.

  5. Selecting a Host DOE Laboratory/Facility | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Regulations and Requirements Human Subjects Protection Program (HSPP) HSPP Home About Institutional Review Boards (IRBs) Education and Resources Regulations and Requirements Ethical Principles Federal Regulations DOE Special Requirements Health Insurance Portability and Accountability Act (HIPAA) Glossary Abbreviations Contact BER Home Contact Information Human Subjects Protection Program U.S. Department of Energy SC-23/Germantown Building 1000 Independence Ave., SW Washington, DC 20585

  6. DOE Special Requirements | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    DOE Special Requirements Human Subjects Protection Program (HSPP) HSPP Home About Institutional Review Boards (IRBs) Education and Resources Regulations and Requirements Ethical Principles Federal Regulations DOE Special Requirements Health Insurance Portability and Accountability Act (HIPAA) Glossary Abbreviations Contact BER Home Contact Information Human Subjects Protection Program U.S. Department of Energy SC-23/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 Regulations

  7. T-527: OpenSC Smart Card Serial Number Multiple Buffer Overflow Vulnerabilities

    Broader source: Energy.gov [DOE]

    OpenSC is prone to multiple buffer-overflow vulnerabilities because the application fails to perform adequate boundary checks on user-supplied input. Attackers may leverage these issues to execute arbitrary code in the context of the application. Failed attacks will cause denial-of-service conditions.

  8. Relativistic Heavy Ion Collider (RHIC) | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Relativistic Heavy Ion Collider (RHIC) Nuclear Physics (NP) NP Home About Research Facilities User Facilities Argonne Tandem Linac Accelerator System (ATLAS) Continuous Electron Beam Accelerator Facility (CEBAF) Relativistic Heavy Ion Collider (RHIC) Project Development Isotope Program Facilities Science Highlights Benefits of NP Funding Opportunities Nuclear Science Advisory Committee (NSAC) Community Resources Contact Information Nuclear Physics U.S. Department of Energy SC-26/Germantown

  9. DOE Award # DE-SC0008085 Close-Out Report for UIUC Portion of Grant

    SciTech Connect (OSTI)

    Teixeira, Kristina Anderson; DeLucia, Evan H

    2014-11-20

    This is the final technical report for the University of Illinois (UIUC) portion of grant # SC0008085 (CARBON DYNAMICS OF FOREST RECOVERY UNDER A CHANGING CLIMATE: FORCINGS, FEEDBACKS, AND IMPLICATIONS FOR EARTH SYSTEM MODELING), which closed June 14, 2014. The grant remains active at the Smithsonian.

  10. Closed Lab Announcements | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Lab Announcements Nuclear Physics (NP) NP Home About Research Facilities Science Highlights Benefits of NP Funding Opportunities Closed Funding Opportunity Announcements (FOAs) Closed Lab Announcements Award Search / Public Abstracts Additional Requirements and Guidance for Digital Data Management Reviews NP Early Career Opportunities Nuclear Science Advisory Committee (NSAC) Community Resources Contact Information Nuclear Physics U.S. Department of Energy SC-26/Germantown Building 1000

  11. miR-182 targets CHL1 and controls tumor growth and invasion in papillary thyroid carcinoma

    SciTech Connect (OSTI)

    Zhu, Hongling; Fang, Jin; Zhang, Jichen; Zhao, Zefei; Liu, Lianyong; Wang, Jingnan; Xi, Qian; Gu, Mingjun

    2014-07-18

    Highlights: miR-182 and CHL1 expression patterns are negatively correlated. CHL1 is a direct target of miR-182 in PTC cells. miR-182 suppression inhibits PTC cell growth and invasion. CHL1 is involved in miR-182-mediated cell behavior. - Abstract: In this study, we investigated the role and underlying mechanism of action of miR-182 in papillary thyroid carcinoma (PTC). Bioinformatics analysis revealed close homolog of LI (CHL1) as a potential target of miR-182. Upregulation of miR-182 was significantly correlated with CHL1 downregulation in human PTC tissues and cell lines. miR-182 suppressed the expression of CHL1 mRNA through direct targeting of the 3?-untranslated region (3?-UTR). Downregulation of miR-182 suppressed growth and invasion of PTC cells. Silencing of CHL1 counteracted the effects of miR-182 suppression, while its overexpression mimicked these effects. Our data collectively indicate that miR-182 in PTC promotes cell proliferation and invasion through direct suppression of CHL1, supporting the potential utility of miR-182 inhibition as a novel therapeutic strategy against PTC.

  12. Non-canonical microRNAs miR-320 and miR-702 promote proliferation in Dgcr8-deficient embryonic stem cells

    SciTech Connect (OSTI)

    Kim, Byeong-Moo; Choi, Michael Y.

    2012-09-21

    Highlights: Black-Right-Pointing-Pointer Embryonic stem cells (ESCs) lacking non-canonical miRNAs proliferate slower. Black-Right-Pointing-Pointer miR-320 and miR-702 are two non-canonical miRNAs expressed in ESCs. Black-Right-Pointing-Pointer miR-320 and miR-702 promote proliferation of Dgcr8-deficient ESCs. Black-Right-Pointing-Pointer miR-320 targets p57 and helps to release Dgcr8-deficient ESCs from G1 arrest. Black-Right-Pointing-Pointer miR-702 targets p21 and helps to release Dgcr8-deficient ESCs from G1 arrest. -- Abstract: MicroRNAs are known to contribute significantly to stem cell phenotype by post-transcriptionally regulating gene expression. Most of our knowledge of microRNAs comes from the study of canonical microRNAs that require two sequential cleavages by the Drosha/Dgcr8 heterodimer and Dicer to generate mature products. In contrast, non-canonical microRNAs bypass the cleavage by the Drosha/Dgcr8 heterodimer within the nucleus but still require cytoplasmic cleavage by Dicer. The function of non-canonical microRNAs in embryonic stem cells (ESCs) remains obscure. It has been hypothesized that non-canonical microRNAs have important roles in ESCs based upon the phenotypes of ESC lines that lack these specific classes of microRNAs; Dicer-deficient ESCs lacking both canonical and non-canonical microRNAs have much more severe proliferation defect than Dgcr8-deficient ESCs lacking only canonical microRNAs. Using these cell lines, we identified two non-canonical microRNAs, miR-320 and miR-702, that promote proliferation of Dgcr8-deficient ESCs by releasing them from G1 arrest. This is accomplished by targeting the 3 Prime -untranslated regions of the cell cycle inhibitors p57 and p21 and thereby inhibiting their expression. This is the first report of the crucial role of non-canonical microRNAs in ESCs.

  13. NuMI proton kicker extraction magnet termination resistor system

    SciTech Connect (OSTI)

    Reeves, S.R.; Jensen, C.C.; /Fermilab

    2005-05-01

    The temperature stability of the kicker magnet termination resistor assembly directly affects the field flatness and amplitude stability. Comprehensive thermal enhancements were made to the existing Main Injector resistor assembly design to satisfy NuMI performance specifications. Additionally, a fluid-processing system utilizing Fluorinert{reg_sign} FC-77 high-voltage dielectric was built to precisely control the setpoint temperature of the resistor assembly from 70 to 120F, required to maintain constant resistance during changing operational modes. The Fluorinert{reg_sign} must be continually processed to remove hazardous breakdown products caused by radiation exposure to prevent chemical attack of system components. Design details of the termination resistor assembly and Fluorinert{reg_sign} processing system are described. Early performance results will be presented.

  14. Management and Operating (M&O) Contracts | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Management and Operating (M&O) Contracts Integrated Support Center (ISC) ISC Home About Services Freedom of Information Act (FOIA) Privacy Act NEPA Documents Contact Information Integrated Support Center Roxanne Purucker U.S. Department of Energy 9800 S. Cass Avenue Argonne, IL 60439 P: (630) 252-2110 Kenneth Tarcza U.S. Department of Energy 200 Administration Road Oak Ridge, TN 37830 P: (865) 576-4444 Acquisition and Assistance Management and Operating (M&O) Contracts Print Text Size: A

  15. Environment, Safety and Health (ES&H) | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Environment, Safety and Health (ES&H) Integrated Support Center (ISC) ISC Home About Services Freedom of Information Act (FOIA) Privacy Act NEPA Documents Contact Information Integrated Support Center Roxanne Purucker U.S. Department of Energy 9800 S. Cass Avenue Argonne, IL 60439 P: (630) 252-2110 Kenneth Tarcza U.S. Department of Energy 200 Administration Road Oak Ridge, TN 37830 P: (865) 576-4444 Services Environment, Safety and Health (ES&H) Print Text Size: A A A FeedbackShare Page

  16. Downregulation of miRNA-30c and miR-203a is associated with hepatitis C virus core protein-induced epithelial–mesenchymal transition in normal hepatocytes and hepatocellular carcinoma cells

    SciTech Connect (OSTI)

    Liu, Dongjing; Wu, Jilin; Liu, Meizhou; Yin, Hui; He, Jiantai; Zhang, Bo

    2015-09-04

    Hepatitis C virus (HCV) Core protein has been demonstrated to induce epithelial–mesenchymal transition (EMT) and is associated with cancer progression of hepatocellular carcinoma (HCC). However, how the Core protein regulates EMT is still unclear. In this study, HCV Core protein was overexpressed by an adenovirus. The protein levels of EMT markers were measured by Western blot. The xenograft animal model was established by inoculation of HepG2 cells. Results showed that ectopic expression of HCV core protein induced EMT in L02 hepatocytes and HepG2 tumor cells by upregulating vimentin, Sanl1, and Snal2 expression and downregulating E-cadherin expression. Moreover, Core protein downregulated miR-30c and miR-203a levels in L02 and HepG2 cells, but artificial expression of miR-30c and miR-203a reversed Core protein-induced EMT. Further analysis showed that ectopic expression of HCV core protein stimulated cell proliferation, inhibited apoptosis, and increased cell migration, whereas artificial expression of miR-30c and miR-203a significantly reversed the role of Core protein in these cell functions in L02 and HepG2 cells. In the HepG2 xenograft tumor models, artificial expression of miR-30c and miR-203a inhibited EMT and tumor growth. Moreover, L02 cells overexpressing Core protein can form tumors in nude mice. In HCC patients, HCV infection significantly shortened patients' survival time, and loss of miR-30c and miR-203 expression correlated with poor survival. In conclusion, HCV core protein downregulates miR-30c and miR-203a expression, which results in activation of EMT in normal hepatocytes and HCC tumor cells. The Core protein-activated-EMT is involved in the carcinogenesis and progression of HCC. Loss of miR-30c and miR-203a expression is a marker for the poor prognosis of HCC. - Highlights: • HCV core protein downregulates miR-30c and miR-203a expression. • Downregulation of miR-30c and miR-203a activates EMT. • Activated-EMT is involved in the

  17. miR-128 and its target genes in tumorigenesis and metastasis

    SciTech Connect (OSTI)

    Li, Molin, E-mail: molin_li@hotmail.com [Dalian Medical University, Dalian 116044 (China); Fu, Weiming [Center for Food Safety and Environmental Technology, Guangzhou Institute of Advanced Technology, Chinese Academy of Sciences, Guangzhou 511458 (China); Wo, Lulu; Shu, Xiaohong [Dalian Medical University, Dalian 116044 (China); Liu, Fang [The second affiliated hospital of Dalian Medical University, Dalian 116023 (China); Li, Chuangang, E-mail: li_chuangang@sina.com [The second affiliated hospital of Dalian Medical University, Dalian 116023 (China)

    2013-12-10

    MicroRNAs (miRNAs) are a class of endogenous, non-coding, 1824 nucleotide length single-strand RNAs that could modulate gene expression at post-transcriptional level. Previous studies have shown that miR-128 enriched in the brain plays an important role in the development of nervous system and the maintenance of normal physical functions. Aberrant expression of miR-128 has been detected in many types of human tumors and its validated target genes are involved in cancer-related biological processes such as cell proliferation, differentiation and apoptosis. In this review, we will summarize the roles of miR-128 and its target genes in tumorigenesis and metastasis. - Highlights: Aberrant expression of miR-128 can be observed in many kinds of malignant tumors. The molecular mechanisms regulating miR-128 expression are elucidated. Roles of miR-128 and its target genes in tumorigenesis and metastasis are summarized.

  18. miR-125b inhibits osteoblastic differentiation by down-regulation of cell proliferation

    SciTech Connect (OSTI)

    Mizuno, Yosuke; Yagi, Ken; Tokuzawa, Yoshimi; Kanesaki-Yatsuka, Yukiko; Suda, Tatsuo; Katagiri, Takenobu; Fukuda, Toru; Maruyama, Masayoshi; Okuda, Akihiko; Amemiya, Tomoyuki; Kondoh, Yasumitsu; Tashiro, Hideo; Okazaki, Yasushi

    2008-04-04

    Although various microRNAs regulate cell differentiation and proliferation, no miRNA has been reported so far to play an important role in the regulation of osteoblast differentiation. Here we describe the role of miR-125b in osteoblastic differentiation in mouse mesenchymal stem cells, ST2, by regulating cell proliferation. The expression of miR-125b was time-dependently increased in ST2 cells, and the increase in miR-125b expression was attenuated in osteoblastic-differentiated ST2 cells induced by BMP-4. The transfection of exogenous miR-125b inhibited proliferation of ST2 cells and caused inhibition of osteoblastic differentiation. In contrast, when the endogenous miR-125b was blocked by transfection of its antisense RNA molecule, alkaline phosphatase activity after BMP-4 treatment was elevated. These results strongly suggest that miR-125b is involved in osteoblastic differentiation through the regulation of cell proliferation.

  19. High performance AlScN thin film based surface acoustic wave devices with large electromechanical coupling coefficient

    SciTech Connect (OSTI)

    Wang, Wenbo; He, Xingli; Ye, Zhi E-mail: jl2@bolton.ac.uk; Wang, Xiaozhi; Mayrhofer, Patrick M.; Gillinger, Manuel; Bittner, Achim; Schmid, Ulrich

    2014-09-29

    AlN and AlScN thin films with 27% scandium (Sc) were synthesized by DC magnetron sputtering deposition and used to fabricate surface acoustic wave (SAW) devices. Compared with AlN-based devices, the AlScN SAW devices exhibit much better transmission properties. Scandium doping results in electromechanical coupling coefficient, K{sup 2}, in the range of 2.0% ∼ 2.2% for a wide normalized thickness range, more than a 300% increase compared to that of AlN-based SAW devices, thus demonstrating the potential applications of AlScN in high frequency resonators, sensors, and high efficiency energy harvesting devices. The coupling coefficients of the present AlScN based SAW devices are much higher than that of the theoretical calculation based on some assumptions for AlScN piezoelectric material properties, implying there is a need for in-depth investigations on the material properties of AlScN.

  20. Overexpression of miR-206 suppresses glycolysis, proliferation and migration in breast cancer cells via PFKFB3 targeting

    SciTech Connect (OSTI)

    Ge, Xin; Lyu, Pengwei; Cao, Zhang; Li, Jingruo; Guo, Guangcheng; Xia, Wanjun; Gu, Yuanting

    2015-08-07

    miRNAs, sorting as non-coding RNAs, are differentially expressed in breast tumor and act as tumor promoters or suppressors. miR-206 could suppress the progression of breast cancer, the mechanism of which remains unclear. The study here was aimed to investigate the effect of miR-206 on human breast cancers. We found that miR-206 was down-regulated while one of its predicted targets, 6-Phosphofructo-2-kinase (PFKFB3) was up-regulated in human breast carcinomas. 17β-estradiol dose-dependently decreased miR-206 expression as well as enhanced PFKFB3 mRNA and protein expression in estrogen receptor α (ERα) positive breast cancer cells. Furthermore, we identified that miR-206 directly interacted with 3′-untranslated region (UTR) of PFKFB3 mRNA. miR-206 modulated PFKFB3 expression in MCF-7, T47D and SUM159 cells, which was influenced by 17β-estradiol depending on ERα expression. In addition, miR-206 overexpression impeded fructose-2,6-bisphosphate (F2,6BP) production, diminished lactate generation and reduced cell proliferation and migration in breast cancer cells. In conclusion, our study demonstrated that miR-206 regulated PFKFB3 expression in breast cancer cells, thereby stunting glycolysis, cell proliferation and migration. - Highlights: • miR-206 was down-regulated and PFKFB3 was up-regulated in human breast carcinomas. • 17β-estradiol regulated miR-206 and PFKFB3 expression in ERα+ cancer cells. • miR-206directly interacted with 3′-UTR of PFKFB3 mRNA. • miR-206 fructose-2,6-bisphosphate (F2,6BP) impeded production and lactate generation. • miR-206 reduced cell proliferation and migration in breast cancer cells.

  1. High-Gradient Tests of the Single-Cell SC Cavity with a Feedback Waveguide

    SciTech Connect (OSTI)

    Yakovlev, V.; Solyak, N.; Wu, G.; Ge, M.; Gonin, I.; Khabiboulline, T.; Ozelis, J.; Rowe, A. [Fermilab, Batavia, IL 60510 (United States); Avrakhov, P.; Kanareykin, A. [Euclid TechLabs, LLC, Solon, Ohio 44139 (United States); Rathke, J. [AES, Medford, NY 11763 (United States)

    2010-11-04

    Use of a superconducting (SC) traveling-wave accelerating (STWA) structure with a small phase advance per cell, rather than a standing-wave structure, may provide a significant increase in the accelerating gradient in the ILC linac [1]. For the same surface electric and magnetic fields, the STWA achieves an accelerating gradient 1.2 larger than TESLA-like standing-wave cavities. In addition, the STWA allows longer acceleration cavities, reducing the number of gaps between them. However, the STWA structure requires a SC feedback waveguide to return the few hundreds of MW of circulating RF power from the structure output to the structure input. A test single-cell cavity with feedback was designed and manufactured to demonstrate the possibility of proper processing to achieve a high accelerating gradient. The first results of high-gradient tests of a prototype 1.3 GHz single-cell cavity with feedback waveguide will be presented.

  2. Supercritical CO2 direct cycle Gas Fast Reactor (SC-GFR) concept.

    SciTech Connect (OSTI)

    Wright, Steven Alan; Parma, Edward J., Jr.; Suo-Anttila, Ahti Jorma; Al Rashdan, Ahmad; Tsvetkov, Pavel Valeryevich; Vernon, Milton E.; Fleming, Darryn D.; Rochau, Gary Eugene

    2011-05-01

    This report describes the supercritical carbon dioxide (S-CO{sub 2}) direct cycle gas fast reactor (SC-GFR) concept. The SC-GFR reactor concept was developed to determine the feasibility of a right size reactor (RSR) type concept using S-CO{sub 2} as the working fluid in a direct cycle fast reactor. Scoping analyses were performed for a 200 to 400 MWth reactor and an S-CO{sub 2} Brayton cycle. Although a significant amount of work is still required, this type of reactor concept maintains some potentially significant advantages over ideal gas-cooled systems and liquid metal-cooled systems. The analyses presented in this report show that a relatively small long-life reactor core could be developed that maintains decay heat removal by natural circulation. The concept is based largely on the Advanced Gas Reactor (AGR) commercial power plants operated in the United Kingdom and other GFR concepts.

  3. AMENDMENT OF SOLICITATION/MODIFICATlON OF CONTRACT MI54 I See...

    National Nuclear Security Administration (NNSA)

    MI54 I See Block 16C I REQ. NO. Babcock & Wilcox Technical Services Pantex, LLC PO Box 30020 Amarillo, TX 79120 2. AMENDMENTIMODIFICATION NO. 1 3. EFFECTIVE DATE 1 4. ...

  4. File:USDA-CE-Production-GIFmaps-MI.pdf | Open Energy Information

    Open Energy Info (EERE)

    MI.pdf Jump to: navigation, search File File history File usage Michigan Ethanol Plant Locations Size of this preview: 463 599 pixels. Other resolution: 464 600 pixels. Full...

  5. Scale of Things Chart | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Scale of Things Chart Basic Energy Sciences (BES) BES Home About Research Facilities Science Highlights Benefits of BES Funding Opportunities Basic Energy Sciences Advisory Committee (BESAC) Community Resources Program Summaries Brochures Reports Accomplishments Presentations BES and Congress Science for Energy Flow Seeing Matter Nano for Energy Scale of Things Chart Contact Information Basic Energy Sciences U.S. Department of Energy SC-22/Germantown Building 1000 Independence Ave., SW

  6. SciDAC Institutes | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    SciDAC Institutes Advanced Scientific Computing Research (ASCR) ASCR Home About Research Applied Mathematics Computer Science Next Generation Networking Scientific Discovery through Advanced Computing (SciDAC) Co-Design SciDAC Institutes ASCR SBIR-STTR Facilities Science Highlights Benefits of ASCR Funding Opportunities Advanced Scientific Computing Advisory Committee (ASCAC) Community Resources Contact Information Advanced Scientific Computing Research U.S. Department of Energy SC-21/Germantown

  7. NBL Program Office CX Determinations | U.S. DOE Office of Science (SC)

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