Sample records for target popu lations

  1. amigdalitis aguda recurrente: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Research Unit), Bordeaux, F-33076, FRANCE. RESUME Dans les analysesecidive de cancer, une fraction de la popu- lation dite " guerie ", ne va jamais rencontrer cet...

  2. Dynamics of an age-structured metapopulation model

    E-Print Network [OSTI]

    2005-10-28T23:59:59.000Z

    address the temporal dynamics that characterize local popu- lations in ... this metapopulation framework, two structures have emerged as being critical in the...

  3. Mon. Not. R. Astron. Soc. 000, 15 (2010) Printed 7 September 2012 (MN LATEX style file v2.2) Secular evolution in action: central values and radial trends in the

    E-Print Network [OSTI]

    Bureau, Martin

    2010-01-01T23:59:59.000Z

    ) galaxies. Either secular evolution affects stellar popu- lations no differently to monolithic collapse radial gradients with linear fits in logR, and using the notation X X/ logR, where X is [Z/H], [/Fe

  4. Evolutionary dynamics in set structured populations Corina E. Tarnitaa

    E-Print Network [OSTI]

    Nowak, Martin A.

    Evolutionary dynamics in set structured populations Corina E. Tarnitaa , Tibor Antala , Hisashi a powerful method to study dynamical population structure: evolutionary set theory. The individuals of popu- lation structure on evolutionary and ecological dynamics. These approaches include spatial models

  5. Target assembly

    DOE Patents [OSTI]

    Lewis, Richard A. (Falls Church, VA)

    1980-01-01T23:59:59.000Z

    A target for a proton beam which is capable of generating neutrons for absorption in a breeding blanket includes a plurality of solid pins formed of a neutron emissive target material disposed parallel to the path of the beam and which are arranged axially in a plurality of layers so that pins in each layer are offset with respect to pins in all other layers, enough layers being used so that each proton in the beam will strike at least one pin with means being provided to cool the pins. For a 300 mA, 1 GeV beam (300 MW), stainless steel pins, 12 inches long and 0.23 inches in diameter are arranged in triangular array in six layers with one sixth of the pins in each layer, the number of pins being such that the entire cross sectional area of the beam is covered by the pins with minimum overlap of pins.

  6. Accelerator target

    DOE Patents [OSTI]

    Schlyer, D.J.; Ferrieri, R.A.; Koehler, C.

    1999-06-29T23:59:59.000Z

    A target includes a body having a depression in a front side for holding a sample for irradiation by a particle beam to produce a radioisotope. Cooling fins are disposed on a backside of the body opposite the depression. A foil is joined to the body front side to cover the depression and sample therein. A perforate grid is joined to the body atop the foil for supporting the foil and for transmitting the particle beam therethrough. A coolant is circulated over the fins to cool the body during the particle beam irradiation of the sample in the depression. 5 figs.

  7. Accelerator target

    DOE Patents [OSTI]

    Schlyer, David J. (Bellport, NY); Ferrieri, Richard A. (Patchogue, NY); Koehler, Conrad (Miller Place, NY)

    1999-01-01T23:59:59.000Z

    A target includes a body having a depression in a front side for holding a sample for irradiation by a particle beam to produce a radioisotope. Cooling fins are disposed on a backside of the body opposite the depression. A foil is joined to the body front side to cover the depression and sample therein. A perforate grid is joined to the body atop the foil for supporting the foil and for transmitting the particle beam therethrough. A coolant is circulated over the fins to cool the body during the particle beam irradiation of the sample in the depression.

  8. First SNS Target Replacement

    E-Print Network [OSTI]

    McDonald, Kirk

    First SNS Target Replacement Experience M. Dayton, M. Rennich, Van Graves, J. DeVore Presented by T.S. Department of Energy AHIP Workshop Oct. 2009 Overview · Initial Target Replacement · Target Maintenance-Battelle for the U.S. Department of Energy AHIP Workshop Oct. 2009 First SNS Target Replacement · Replacement

  9. MECO Production Target Developments

    E-Print Network [OSTI]

    McDonald, Kirk

    be reoptimized Tungsten target Simulations of design parameters with GEANT3 indicate that both production targetMECO Production Target Developments James L. Popp University of California, Irvine NuFact'03 Columbia, June, 2003 #12;June, 2003J.L.Popp, UCI MECO Production Target 2 MECO Collaboration Institute

  10. Polarized internal target apparatus

    DOE Patents [OSTI]

    Holt, R.J.

    1984-10-10T23:59:59.000Z

    A polarized internal target apparatus with a polarized gas target of improved polarization and density (achieved by mixing target gas atoms with a small amount of alkali metal gas atoms, and passing a high intensity polarized light source into the mixture to cause the alkali metal gas atoms to become polarized which interact in spin exchange collisions with target gas atoms yielding polarized target gas atoms) is described.

  11. Electrically charged targets

    DOE Patents [OSTI]

    Goodman, Ronald K. (Livermore, CA); Hunt, Angus L. (Alamo, CA)

    1984-01-01T23:59:59.000Z

    Electrically chargeable laser targets and method for forming such charged targets in order to improve their guidance along a predetermined desired trajectory. This is accomplished by the incorporation of a small amount of an additive to the target material which will increase the electrical conductivity thereof, and thereby enhance the charge placed upon the target material for guidance thereof by electrostatic or magnetic steering mechanisms, without adversely affecting the target when illuminated by laser energy.

  12. Magnetically attached sputter targets

    DOE Patents [OSTI]

    Makowiecki, D.M.; McKernan, M.A.

    1994-02-15T23:59:59.000Z

    An improved method and assembly for attaching sputtering targets to cathode assemblies of sputtering systems which includes a magnetically permeable material is described. The magnetically permeable material is imbedded in a target base that is brazed, welded, or soldered to the sputter target, or is mechanically retained in the target material. Target attachment to the cathode is achieved by virtue of the permanent magnets and/or the pole pieces in the cathode assembly that create magnetic flux lines adjacent to the backing plate, which strongly attract the magnetically permeable material in the target assembly. 11 figures.

  13. High Power Cryogenic Targets

    SciTech Connect (OSTI)

    Gregory Smith

    2011-08-01T23:59:59.000Z

    The development of high power cryogenic targets for use in parity violating electron scattering has been a crucial ingredient in the success of those experiments. As we chase the precision frontier, the demands and requirements for these targets have grown accordingly. We discuss the state of the art, and describe recent developments and strategies in the design of the next generation of these targets.

  14. Journees des Jeunes Chercheurs 11`eme edition, 8-9 Avril 1999, Lausanne 145 ROMERO: UN P `ELERINAGE ROBOTIQUE `A SANTA FE

    E-Print Network [OSTI]

    Teuscher, Christof

    disposition une popu- lation de vrais robots. Afin, de rendre r´ealit´e ce r^eve, notre travail poursuit deux buts: (1) construire un robot bon march´e, modulaire et extensible et (2) utiliser une population de ces robots pour faire des exp´eriences dans le domaine de la robotique ´evolutive. Ce papier pr

  15. p s sreprints www.interscience.wiley.com

    E-Print Network [OSTI]

    the current whose direc- tion is controlled by the relative phase between the phase- locked laser excitation of coherent control and photoemission spectroscopy. We have ap- plied this technique for electrons excited with intraband accelerations into the model, the observed phase dependence of the popu- lation and of the current

  16. Proc. Natl. Acad. Sci. USA Vol. 94, pp. 18621865, March 1997

    E-Print Network [OSTI]

    Brown, Andrew Leigh

    tested for departure from neutral- ity because of mutationselection balance. None of the sam- ples sites. These results suggest that the population genetics of HIV are best described by stochastic models). In contrast, stochastic, finite popu- lation models recognize the importance of sampling in evolu- tion

  17. Short communication Dynamics of microbubble oscillators with delay coupling

    E-Print Network [OSTI]

    Rand, Richard H.

    of systems of coupled microbubbles in- volves taking into account the speed of sound in the liquid, which to travel from one bubble to another through the liquid medium that surrounds them. Using techniques from; coupled laser systems, high-speed milling, popu- lation dynamics and gene expression are some examples

  18. Molecular Ecology (2008) 17, 24172429 doi: 10.1111/j.1365-294X.2008.03751.x 2008 The Authors

    E-Print Network [OSTI]

    2008-01-01T23:59:59.000Z

    the hypothesis of a long-term separation of Eastern (Balkans and Carpathians) and Western (Alps and Pyrenees found in the European Alps, the Carpathians, the Pyrenees and in some of the Balkan Mountains was likely located. The Pyrenean popu- lations are nested within the western Alps group and show a low level

  19. Correspondence All articles available online at http://www.salamandra-journal.com

    E-Print Network [OSTI]

    Alvarez, Nadir

    ) with stripes on the Canary Islands Christophe Dufresnes 1 , Laura Gangoso 2 , Nicolas Perrin 1 & Matthias Stck and the Canary Islands. As indicat- ed by its English vernacular name, the stripeless tree frog is very well report on a remarkable exception in several popu- lations from the Canary Islands where individuals

  20. Adaptively Choosing Neighbourhood Bests Using Species in a Particle Swarm Optimizer for

    E-Print Network [OSTI]

    Li, Xiaodong

    , for some practical reasons, it is often desirable for the designer to choose from a diverse set of good with best known positions to guide the swarm population to converge to a single optimum in the search space. How to choose the best-fit particle to guide each particle in the swarm popu- lation is a critical

  1. Ecology, 82(2), 2001, pp. 567579 2001 by the Ecological Society of America

    E-Print Network [OSTI]

    Station, N-4817 His, Norway 6Norwegian Institute for Nature Research, P.O. Box 736, Sentrum, N-0105 Oslo the level of direct and delayed density-dependent mortality (DDM) of 11 popu- lations from the Norwegian Skagerrak coast. The parameters were estimated using a mod- eling approach that explicitly incorporates

  2. &p.1:Abstract Previous study of Cupressaceae pollen in the Tulsa atmosphere during December and January suggest-

    E-Print Network [OSTI]

    Levetin, Estelle

    &p.1:Abstract Previous study of Cupressaceae pollen in the Tulsa atmosphere during December outside of the local season at Tulsa. Pollen concentrations are intermittent and correspond to days that pollen is being trans- ported over long distances from the mountain cedar popu- lations to Tulsa

  3. Introduction to the special issue: Understanding and linking the biophysical, socioeconomic and geopolitical effects of dams

    E-Print Network [OSTI]

    Tullos, Desiree

    , socioeconomic and geopolitical effects of dams 1. Introduction Dams have made important contributions to human develop- ment, and the benefits derived from them have been considerable (World Commission on Dams, 2000). With the rising global popu- lation and desire to increase quality of life, dams are prominently staged to deliver

  4. Pharaxonotha portophylla (Coleoptera: Erotylidae), new species and pollinator of Zamia (Zamiaceae) in Puerto Rico

    E-Print Network [OSTI]

    Franz, Nico M.

    ) in Puerto Rico NICO M. FRANZ 1,3 AND PAUL E. SKELLEY 2 1 Department of Biology, PO Box 9012, University of Puerto Rico, Mayagez, PR 00681, U.S.A. 2 Florida State Collection of Arthropods, Florida Department 2000). In particular the popu- lation structure of Z. amblyphyllidia in northern Puerto Rico is well

  5. 17. METAPOPULATION DYNAMICS OF

    E-Print Network [OSTI]

    17. METAPOPULATION DYNAMICS OF INFECTIOUS DISEASES Matt J. Keeling, Ottar N. Bjrnstad, and Bryan T resonances for the dynamics of parasites. This is particularly true for microparasitic infections" growth of the parasite population. Thus, at the scale of the host popu- lation, infectious dynamics bears

  6. EcoMata : Un logiciel d'aide la dcision pour amliorer la gestion des cosystmes

    E-Print Network [OSTI]

    Boyer, Edmond

    EcoMata : Un logiciel d'aide la dcision pour amliorer la gestion des cosystmes Yulong Zhao1 complexe comme dans le cas du contrle de popu- lation. La dynamique d'volution de chaque population (dans notre cas les espces de poisson) est relativement facile exprimer de manire qualitative. En revanche

  7. A POSSIBLE LOCAL COUNTERPART TO THE EXCESS POPULATION OF FAINT BLUE GALAXIES

    E-Print Network [OSTI]

    McGaugh, Stacy

    A POSSIBLE LOCAL COUNTERPART TO THE EXCESS POPULATION OF FAINT BLUE GALAXIES STACY S. MCGAUGH of galaxies to very faint magnitudes have revealed a popu- lation of blue galaxies at intermediate redshift1 5 brightness galaxies have properties very similar to those of the excess blue population10;11, and re- cent

  8. Target Cost Management Strategy

    E-Print Network [OSTI]

    Okano, Hiroshi

    1996-01-01T23:59:59.000Z

    Target cost management (TCM) is an innovation of Japanese management accounting system and by common sense has been considered with great interest by practitioners. Nowadays, TCM related

  9. Neutrino Factory Target Vessel

    E-Print Network [OSTI]

    McDonald, Kirk

    by UT-Battelle for the U.S. Department of Energy Target Vessel Update 26 June 2012 Cooling Channel in both walls for draining · Downstream end can be shortened, assuming the window cooling is adequate #12;11 Managed by UT-Battelle for the U.S. Department of Energy Target Vessel Update 26 June 2012 Remote Handling

  10. SNS Target Systems Operational

    E-Print Network [OSTI]

    McDonald, Kirk

    a failed gas seal on the shaft and leaking oil seals but has operated well since then · The moderator 7.5 k First target replacement · No observed corrosion · Internal Boroscope examination in progress · ~ 50 mm

  11. Cooled particle accelerator target

    DOE Patents [OSTI]

    Degtiarenko, Pavel V.

    2005-06-14T23:59:59.000Z

    A novel particle beam target comprising: a rotating target disc mounted on a retainer and thermally coupled to a first array of spaced-apart parallel plate fins that extend radially inwardly from the retainer and mesh without physical contact with a second array of spaced-apart parallel plate fins that extend radially outwardly from and are thermally coupled to a cooling mechanism capable of removing heat from said second array of spaced-apart fins and located within the first array of spaced-apart parallel fins. Radiant thermal exchange between the two arrays of parallel plate fins provides removal of heat from the rotating disc. A method of cooling the rotating target is also described.

  12. Foam encapsulated targets

    DOE Patents [OSTI]

    Nuckolls, John H. (Livermore, CA); Thiessen, Albert R. (Livermore, CA); Dahlbacka, Glen H. (Livermore, CA)

    1983-01-01T23:59:59.000Z

    Foam encapsulated laser-fusion targets wherein a quantity of thermonuclear fuel is embedded in low density, microcellular foam which serves as an electron conduction channel for symmetrical implosion of the fuel by illumination of the target by one or more laser beams. The fuel, such as DT, is contained within a hollow shell constructed of glass, for example, with the foam having a cell size of preferably no greater than 2 .mu.m, a density of 0.065 to 0.6.times.10.sup.3 kg/m.sup.3, and external diameter of less than 200 .mu.m.

  13. Targeted polypeptide degradation

    DOE Patents [OSTI]

    Church, George M. (Brookline, MA); Janse, Daniel M. (Brookline, MA)

    2008-05-13T23:59:59.000Z

    This invention pertains to compositions, methods, cells and organisms useful for selectively localizing polypeptides to the proteasome for degradation. Therapeutic methods and pharmaceutical compositions for treating disorders associated with the expression and/or activity of a polypeptide by targeting these polypeptides for degradation, as well as methods for targeting therapeutic polypeptides for degradation and/or activating therapeutic polypeptides by degradation are provided. The invention provides methods for identifying compounds that mediate proteasome localization and/or polypeptide degradation. The invention also provides research tools for the study of protein function.

  14. Flight Path Target 2

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Science (SC) Environmental Assessments (EA)Budget(DANCE) Target 1 Flight Path flightTargetL -

  15. Flight Path Target 2

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Science (SC) Environmental Assessments (EA)Budget(DANCE) Target 1 Flight Path flightTargetL - -

  16. Flight Path Target 2

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Science (SC) Environmental Assessments (EA)Budget(DANCE) Target 1 Flight Path flightTargetL - -

  17. Flight Path Target 2

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Science (SC) Environmental Assessments (EA)Budget(DANCE) Target 1 Flight Path flightTargetL - - -

  18. Future Fixed Target Facilities

    SciTech Connect (OSTI)

    Melnitchouk, Wolodymyr

    2009-01-01T23:59:59.000Z

    We review plans for future fixed target lepton- and hadron-scattering facilities, including the 12 GeV upgraded CEBAF accelerator at Jefferson Lab, neutrino beam facilities at Fermilab, and the antiproton PANDA facility at FAIR. We also briefly review recent theoretical developments which will aid in the interpretation of the data expected from these facilities.

  19. Targeted radionuclide therapy

    SciTech Connect (OSTI)

    Williams, Lawrence E.; DeNardo, Gerald L.; Meredith, Ruby F. [Radiology Division, City of Hope National Medical Center, Duarte, California 91010 (United States); Internal Medicine, University of California Davis Medical Center, 1508 Alhambra Boulevard, Suite 3100, Sacramento, California 95816 (United States); Department of Radiation Oncology, Wallace Tumor Institute WTI No. 117, University of Alabama at Birmingham, Birmingham, Alabama 35294 (United States)

    2008-07-15T23:59:59.000Z

    Targeted radionuclide therapy (TRT) seeks molecular and functional targets within patient tumor sites. A number of agents have been constructed and labeled with beta, alpha, and Auger emitters. Radionuclide carriers spanning a broad range of sizes; e.g., antibodies, liposomes, and constructs such as nanoparticles have been used in these studies. Uptake, in percent-injected dose per gram of malignant tissue, is used to evaluate the specificity of the targeting vehicle. Lymphoma (B-cell) has been the primary clinical application. Extension to solid tumors will require raising the macroscopic absorbed dose by several-fold over values found in present technology. Methods that may effect such changes include multistep targeting, simultaneous chemotherapy, and external sequestration of the agent. Toxicity has primarily involved red marrow so that marrow replacement can also be used to enhance future TRT treatments. Correlation of toxicities and treatment efficiency has been limited by relatively poor absorbed dose estimates partly because of using standard (phantom) organ sizes. These associations will be improved in the future by obtaining patient-specific organ size and activity data with hybrid SPECT/CT and PET/CT scanners.

  20. Solid Target Options S. Childress

    E-Print Network [OSTI]

    McDonald, Kirk

    power is higher than for existing solid target designs - but not by a large factor. · NuMI graphite beam power) · High beam power solid targets frequently use higher z materials for increased yield plusSolid Target Options NuFACT'00 S. Childress Solid Target Options · The choice of a primary beam

  1. ISAC target vacuum system

    SciTech Connect (OSTI)

    Yosifov, Dimo; Sekachev, Igor [TRIUMF, Canada's National Laboratory for Particle and Nuclear Physics, Vancouver, British Columbia V6T 2A3 (Canada)

    2006-07-15T23:59:59.000Z

    The Isotope Separator and Accelerator (ISAC) facility at TRIUMF has been in full operation since 1999. The ISAC east and west targets use proton beam from the cyclotron to produce various radioactive isotopes, which are then ionized and extracted. The ions are then passed through the mass separator and selected ions are transferred to the low energy experiments or injected into a radio frequency quadrupole accelerator. The accompanying radioactive contamination from the production of radioactive ions requires a complex vacuum system. The main target vacuum space consists of two semiseparate (primary and secondary) volumes pumped by turbo-molecular pumps. The primary volume uses four pumps while the secondary volume uses two pumps. Two hermetic rotary vane pumps are used as backing pumps. The nominal vacuum in both volumes is about 1.33x10{sup -4} Pa (1.0x10{sup -6} Torr). The pressure is monitored by two cold cathode and two hot filament ion gauges. The cold cathode gauges are used to interlock the system, which is critical during the bake out of the target and beam production. The exhaust gas from the vacuum pumps can be radioactive. Three gas storage tanks (decay tanks) are used for temporary storage of the radioactive exhaust and its controlled release to the atmosphere. Gas-species insensitive membrane gauges are used for monitoring the pressure in the storage tanks. This article describes the details of the ISAC target vacuum system as well as some procedures related to the handling of the exhaust gas with traces of radioactive contamination produced by the targets.

  2. Target: Subpoena (2010-SE-2001)

    Broader source: Energy.gov [DOE]

    DOE issued a Subpoena for Information and Production of Documents to Target Corporation requesting information regarding the compliance of various torchieres Target has distributed in commerce in the U.S.

  3. Non-PGM Target Update

    Broader source: Energy.gov (indexed) [DOE]

    targets that need to be met are cost, efficiency, and durability. A secondary target is heat rejection at rated power. (ANL) * Given that for current Pt systems catalyst cost is ...

  4. Target | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov YouKizildere IRaghuraji Agro Industries PvtStratosolar Jump to:Holdings Co08.0Information ExpansionTarget GmbH Jump

  5. Cancer Cell Targeting Androgen Receptor

    E-Print Network [OSTI]

    Liu, Xiaole Shirley

    in the development of endo- crine therapies targeting estrogen production or ER for both breast cancer treatment targeting of AR, Wnt or HER2 signaling impairs androgen-stimulated tumor cell growth suggesting potential. Therapies targeting HER2 such as trastuzumab are becoming increasingly important in the treatment of HER2

  6. Rotating Target Development for SNS Second Target Station

    SciTech Connect (OSTI)

    McManamy, Thomas J [ORNL; Rennich, Mark J [ORNL; Crawford, Roy K [ORNL; Geoghegan, Patrick J [ORNL; Janney, Jim G [ORNL

    2010-01-01T23:59:59.000Z

    A rotating target for the second target station (STS) at SNS has been identified as an option along with a mercury target. Evaluation of the rotating target alternative for STS has started at 1.5 MW which is considered an upper bound for the power. Previous preconceptual design work for a 3 MW rotating target is being modified for the lower power level. Transient thermal analysis for a total loss of active water cooling has been done for a simplified 2D model of the target and shielding monolith which shows that peak temperatures are well below the level at which tungsten vaporization by steam could exceed site boundary dose limits. Design analysis and integration configuration studies have been done for the target-moderator-reflector assembly which maximizes the number of neutron beam lines and provides for replacement of the target and moderators. Target building hot cell arrangement for this option will be described. An option for operation in rough vacuum without a proton beam window using Ferro fluid seals on a vertical shaft is being developed. A full scale prototypic drive module based on the 3 MW preconceptual design has been fabricated and successfully tested with a shaft and mock up target supplied by the ESS-Bilbao team. Overall planning leading to decision between mercury and the rotating target in 2011 will be discussed

  7. Target detection portal

    DOE Patents [OSTI]

    Linker, Kevin L. (Albuquerque, NM); Brusseau, Charles A. (Tijeras, NM)

    2002-01-01T23:59:59.000Z

    A portal apparatus for screening persons or objects for the presence of trace amounts of target substances such as explosives, narcotics, radioactive materials, and certain chemical materials. The portal apparatus can have a one-sided exhaust for an exhaust stream, an interior wall configuration with a concave-shape across a horizontal cross-section for each of two facing sides to result in improved airflow and reduced washout relative to a configuration with substantially flat parallel sides; air curtains to reduce washout; ionizing sprays to collect particles bound by static forces, as well as gas jet nozzles to dislodge particles bound by adhesion to the screened person or object. The portal apparatus can be included in a detection system with a preconcentrator and a detector.

  8. PDFs for nuclear targets

    E-Print Network [OSTI]

    Karol Kovarik

    2010-06-25T23:59:59.000Z

    Understanding nuclear effects in parton distribution functions (PDF) is an essential component needed to determine the strange and anti-strange quark contributions in the proton. In addition Nuclear Parton Distribution Functions (NPDF) are critically important for any collider experiment with nuclei (e.g. RHIC, ALICE). Here two next-to-leading order chi^2-analyses of NPDF are presented. The first uses neutral current charged-lepton Deeply Inelastic Scattering (DIS) and Drell-Yan data for several nuclear targets and the second uses neutrino-nucleon DIS data. We compare the nuclear corrections factors (F_2^Fe/F_2^D) for the charged-lepton data with other results from the literature. In particular, we compare and contrast fits based upon the charged-lepton DIS data with those using neutrino-nucleon DIS data.

  9. Multiple target laser ablation system

    DOE Patents [OSTI]

    Mashburn, Douglas N. (Knoxville, TN)

    1996-01-01T23:59:59.000Z

    A laser ablation apparatus and method are provided in which multiple targets consisting of material to be ablated are mounted on a movable support. The material transfer rate is determined for each target material, and these rates are stored in a controller. A position detector determines which target material is in a position to be ablated, and then the controller controls the beam trigger timing and energy level to achieve a desired proportion of each constituent material in the resulting film.

  10. Multiple target laser ablation system

    DOE Patents [OSTI]

    Mashburn, D.N.

    1996-01-09T23:59:59.000Z

    A laser ablation apparatus and method are provided in which multiple targets consisting of material to be ablated are mounted on a movable support. The material transfer rate is determined for each target material, and these rates are stored in a controller. A position detector determines which target material is in a position to be ablated, and then the controller controls the beam trigger timing and energy level to achieve a desired proportion of each constituent material in the resulting film. 3 figs.

  11. Target Space Duality III: Potentials

    E-Print Network [OSTI]

    Orlando Alvarez; Blazej Ruszczycki

    2007-12-31T23:59:59.000Z

    We generalize previous results on target space duality to the case where there are background fields and the sigma model lagrangian has a potential function.

  12. Occupational Change Among Spanish-Americans in Atascosa County and San Antonio, Texas.

    E-Print Network [OSTI]

    Skrabanek, R. L.; Rapton, Avra

    1966-01-01T23:59:59.000Z

    from farm work towarcl the blue-collar jobs. A few farm laborers became operators of their own farm. Among household heads who had started their careers in nonfarm jobs, however, there was little up- ward occupational mobility. Among the San... their skills sufficiently to match those of the total popu- lation, and they occupied a position midway between their parents and the total population. For example, a. in San Antonio the proportion of laborers, both farm and nonfarm, among male younger...

  13. Border Patrol

    E-Print Network [OSTI]

    Unknown

    2011-09-05T23:59:59.000Z

    (Kus#2;u Bonnenfant, 2012). The widespread Kazakh diaspora heeded this call, migrating from Uzbekistan, Russia, China, Mongolia and elsewhere seeking to return to the traditional Kazakh homeland. From the state perspective, repatriation suc... (immobile). Beginning in the early 1990s, following the opening of borders across Central Asia, a sizable portion of the Kazakh minority popu- lation in western Mongolia migrated to Kazakhstan. The rationale for leaving was clear the loss of a central...

  14. Chromosomal polymorphism in Oedaleonotus enigma (Scudder) (Orthoptera: Acrididae

    E-Print Network [OSTI]

    Haynie, Susan Elaine

    1972-01-01T23:59:59.000Z

    pericentric inversions, a fusion between two telocentrics yielding a metacentric, and a heterochromatic supernumerary chromosome segment. B-chromosomes were also found in some individuals from three different popu- lations. Statistical analyses of each... of the ten populations also showed no significant differences between populations. The fusion polymorphism and inversion polymorphism in chromosome 8 were also simultaneously analyzed. A slight deviation from the expected values was found. From...

  15. The propagation of the Attwater prairie chicken in captivity

    E-Print Network [OSTI]

    Watkins, Roy Michael

    1971-01-01T23:59:59.000Z

    to near Brownsville, Texas. These birds were reported to exist in the hundreds of thousands, even to the point of menacing crop production. The first reliable sur- vey was made in 1937 in which 8, 700 prairie chickens were reported to exist. Thirty... years later the same researcher reported the number of birds to be only 1, 070. The Attwater prairie chicken no longer exists in Louisiana and occurs only in small disjunct popu- lations between Houston and Victoria, Texas. Thus, The following...

  16. Target Proposal Feb. 15, 2000

    E-Print Network [OSTI]

    McDonald, Kirk

    enables simpler system design, compatible with high magnetic field, no toxic waste, replaceable option initial approach can be very important in progress toward a real facility #12; Target Proposal Feb. 15 Target Survivability (cont) . Cooling 23 kW per MW of beam power -- A significant advantage of carbon

  17. VERTEX CHAMBERS TARGET CELL CALORIMETER

    E-Print Network [OSTI]

    DRIFT VC 1/2 FC 1/2 VERTEX CHAMBERS TARGET CELL DVC MC 13 HODOSCOPE H0 MONITOR BC 1/2 BC 3/4 TRD at Threashold Lambda Physics (u L spin transfer) Motivation: W L Target cell e beam L p p e Elastic: Peltier elements ( T ~ 20C ) Custom built electronics + HELIX chips low autgassing (

  18. Possible Target Options Michael A. Green

    E-Print Network [OSTI]

    McDonald, Kirk

    Possible Target Options Michael A. Green WATER COOLED SOLID TARGETS For high energy drivers, a desirable target material should have a medium to high Z. For low energy drivers the targe should be made are obvious medium Z target materials. A less obvious candidate is a titanium or niobium-titanium alloy target

  19. Targets and methods for target preparation for radionuclide production

    DOE Patents [OSTI]

    Zhuikov, Boris L; Konyakhin, Nicolai A; Kokhanyuk, Vladimir M; Srivastava, Suresh C

    2012-10-16T23:59:59.000Z

    The invention relates to nuclear technology, and to irradiation targets and their preparation. One embodiment of the present invention includes a method for preparation of a target containing intermetallic composition of antimony Ti--Sb, Al--Sb, Cu--Sb, or Ni--Sb in order to produce radionuclides (e.g., tin-117 m) with a beam of accelerated particles. The intermetallic compounds of antimony can be welded by means of diffusion welding to a copper backing cooled during irradiation on the beam of accelerated particles. Another target can be encapsulated into a shell made of metallic niobium, stainless steel, nickel or titanium cooled outside by water during irradiation. Titanium shell can be plated outside by nickel to avoid interaction with the cooling water.

  20. Monotonic Target Assignment for Robotic Networks

    E-Print Network [OSTI]

    Smith, Stephen L; Bullo, Francesco

    2009-01-01T23:59:59.000Z

    Target assignment for robotic networks: Worst-case andTARGET ASSIGNMENT FOR ROBOTIC NETWORKS [6] H. W. Kuhn, TheTarget Assignment for Robotic Networks Stephen L. Smith,

  1. Targets

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of ScienceandMesa del SolStrengthening a solidSynthesis of 2D AlloysTrails TakingRTape Mounts Last

  2. Multishell inertial confinement fusion target

    DOE Patents [OSTI]

    Holland, James R. (Butler, PA); Del Vecchio, Robert M. (Vandergrift, PA)

    1984-01-01T23:59:59.000Z

    A method of fabricating multishell fuel targets for inertial confinement fusion usage. Sacrificial hemispherical molds encapsulate a concentric fuel pellet which is positioned by fiber nets stretched tautly across each hemispherical mold section. The fiber ends of the net protrude outwardly beyond the mold surfaces. The joint between the sacrificial hemispheres is smoothed. A ceramic or glass cover is then deposited about the finished mold surfaces to produce an inner spherical surface having continuously smooth surface configuration. The sacrificial mold is removed by gaseous reaction accomplished through the porous ceramic cover prior to enclosing of the outer sphere by addition of an outer coating. The multishell target comprises the inner fuel pellet concentrically arranged within a surrounding coated cover or shell by fiber nets imbedded within the cover material.

  3. Multishell inertial confinement fusion target

    DOE Patents [OSTI]

    Holland, James R. (Butler, PA); Del Vecchio, Robert M. (Vandergrift, PA)

    1987-01-01T23:59:59.000Z

    A method of fabricating multishell fuel targets for inertial confinement fusion usage. Sacrificial hemispherical molds encapsulate a concentric fuel pellet which is positioned by fiber nets stretched tautly across each hemispherical mold section. The fiber ends of the net protrude outwardly beyond the mold surfaces. The joint between the sacrificial hemispheres is smoothed. A ceramic or glass cover is then deposited about the finished mold surfaces to produce an inner spherical surface having continuously smooth surface configuration. The sacrificial mold is removed by gaseous reactions accomplished through the porous ceramic cover prior to enclosing of the outer sphere by addition of an outer coating. The multishell target comprises the inner fuel pellet concentrically arranged within a surrounding coated cover or shell by fiber nets imbedded within the cover material.

  4. LIFE Target Fabrication Research Plan Sept 2008

    SciTech Connect (OSTI)

    Miles, R; Biener, J; Kucheyev, S; Montesanti, R; Satcher, J; Spadaccini, C; Rose, K; Wang, M; Hamza, A; Alexander, N; Brown, L; Hund, J; Petzoldt, R; Sweet, W; Goodin, D

    2008-11-10T23:59:59.000Z

    The target-system for the baseline LIFE fast-ignition target was analyzed to establish a preliminary estimate for the costs and complexities involved in demonstrating the technologies needed to build a prototype LIFE plant. The baseline fast-ignition target upon which this analysis was developed is shown in Figure 1.0-1 below. The LIFE target-system incorporates requirements for low-cost, high throughput manufacture, high-speed, high accuracy injection of the target into the chamber, production of sufficient energy from implosion and recovery and recycle of the imploded target material residue. None of these functions has been demonstrated to date. Existing target fabrication techniques which lead to current 'hot spot' target costs of {approx}$100,000 per target and at a production rate of 2/day are unacceptable for the LIFE program. Fabrication techniques normally used for low-cost, low accuracy consumer products such as toys must be adapted to the high-accuracy LIFE target. This will be challenge. A research program resulting is the demonstration of the target-cycle technologies needed for a prototype LIFE reactor is expected to cost {approx}$51M over the course of 5 years. The effort will result in targets which will cost an estimated $0.23/target at a rep-rate of 20 Hz or about 1.73M targets/day.

  5. Target 4 Flight Path 90L (FIRE House) Target 4 Flight Path...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and industrial research. LANSCE has two spallation neutron sources: the Manuel Lujan Jr. Neutron Scattering Center (Target-1) and the Weapons Neutron Research facility (Target-4)....

  6. Qualified Target Industry Tax Refund (Florida)

    Broader source: Energy.gov [DOE]

    The Qualified Target Industry Tax Refund incentive is available for companies that create high wage jobs in targeted high value-added industries. The incentive refunds up to $3,000 per new full...

  7. Targets and processes for fabricating same

    DOE Patents [OSTI]

    Cowan, Thomas (Dresden, DE); Malekos, Steven (Reno, NV); Korgan, Grant (Reno, NV); Adams, Jesse (Reno, NV); Sentoku, Yasuhiko (Reno, NV); Le Galloudec, Nathalie (Reno, NV); Fuchs, Julien (Paris, FR)

    2012-07-24T23:59:59.000Z

    In particular embodiments, the present disclosure provides targets including a metal layer and defining a hollow inner surface. The hollow inner surface has an internal apex. The distance between at least two opposing points of the internal apex is less than about 15 .mu.m. In particular examples, the distance is less than about 1 .mu.m. Particular implementations of the targets are free standing. The targets have a number of disclosed shaped, including cones, pyramids, hemispheres, and capped structures. The present disclosure also provides arrays of such targets. Also provided are methods of forming targets, such as the disclosed targets, using lithographic techniques, such as photolithographic techniques. In particular examples, a target mold is formed from a silicon wafer and then one or more sides of the mold are coated with a target material, such as one or more metals.

  8. Review of the Renewable Energy Target

    E-Print Network [OSTI]

    Peters, Richard

    Review of the Renewable Energy Target Response to Expert Panel's Call for Submissions Paper #12;NSW Government Submission to the Review of the Renewable Energy Target, May 2014 2/20 Contents EXECUTIVE SUMMARY........................................................................................................................... 3 RENEWABLE ENERGY IN NSW

  9. Nanoparticles for targeting the infarcted heart

    E-Print Network [OSTI]

    Dvir, Tal

    We report a nanoparticulate system capable of targeting the heart after myocardial infarction (MI). Targeting is based on overexpression of angiotensin II type 1 (AT1) receptor in the infarcted heart. Liposomes 142 nm in ...

  10. PLUTONIUM-238 PRODUCTION TARGET DESIGN STUDIES

    SciTech Connect (OSTI)

    Hurt, Christopher J [ORNL; Wham, Robert M [ORNL; Hobbs, Randall W [ORNL; Owens, R Steven [ORNL; Chandler, David [ORNL; Freels, James D [ORNL; Maldonado, G Ivan [ORNL

    2014-01-01T23:59:59.000Z

    A new supply chain is planned for plutonium-238 using existing reactors at the Oak Ridge National Laboratory (ORNL) and Idaho National Laboratory (INL) and existing chemical recovery facilities at ORNL. Validation and testing activities for new irradiation target designs have been conducted in three phases over a 2 year period to provide data for scale-up to production. Target design, qualification, target fabrication, and irradiation of fully-loaded targets have been accomplished. Data from post-irradiation examination (PIE) supports safety analysis and irradiation of future target designs.

  11. Ignition of deuterium-tritium fuel targets

    DOE Patents [OSTI]

    Musinski, D.L.; Mruzek, M.T.

    1991-08-27T23:59:59.000Z

    Disclosed is a method of igniting a deuterium-tritium ICF fuel target to obtain fuel burn in which the fuel target initially includes a hollow spherical shell having a frozen layer of DT material at substantially uniform thickness and cryogenic temperature around the interior surface of the shell. The target is permitted to free-fall through a target chamber having walls heated by successive target ignitions, so that the target is uniformly heated during free-fall to at least partially melt the frozen fuel layer and form a liquid single-phase layer or a mixed liquid/solid bi-phase layer of substantially uniform thickness around the interior shell surface. The falling target is then illuminated from exteriorly of the chamber while the fuel layer is at substantially uniformly single or bi-phase so as to ignite the fuel layer and release energy therefrom. 5 figures.

  12. Ignition of deuterium-trtium fuel targets

    DOE Patents [OSTI]

    Musinski, Donald L. (Saline, MI); Mruzek, Michael T. (Britton, MI)

    1991-01-01T23:59:59.000Z

    A method of igniting a deuterium-tritium ICF fuel target to obtain fuel burn in which the fuel target initially includes a hollow spherical shell having a frozen layer of DT material at substantially uniform thickness and cryogenic temperature around the interior surface of the shell. The target is permitted to free-fall through a target chamber having walls heated by successive target ignitions, so that the target is uniformly heated during free-fall to at least partially melt the frozen fuel layer and form a liquid single-phase layer or a mixed liquid/solid bi-phase layer of substantially uniform thickness around the interior shell surface. The falling target is then illuminated from exteriorly of the chamber while the fuel layer is at substantially uniformly single or bi-phase so as to ignite the fuel layer and release energy therefrom.

  13. Fabrication of boron sputter targets

    DOE Patents [OSTI]

    Makowiecki, Daniel M. (Livermore, CA); McKernan, Mark A. (Livermore, CA)

    1995-01-01T23:59:59.000Z

    A process for fabricating high density boron sputtering targets with sufficient mechanical strength to function reliably at typical magnetron sputtering power densities and at normal process parameters. The process involves the fabrication of a high density boron monolithe by hot isostatically compacting high purity (99.9%) boron powder, machining the boron monolithe into the final dimensions, and brazing the finished boron piece to a matching boron carbide (B.sub.4 C) piece, by placing aluminum foil there between and applying pressure and heat in a vacuum. An alternative is the application of aluminum metallization to the back of the boron monolithe by vacuum deposition. Also, a titanium based vacuum braze alloy can be used in place of the aluminum foil.

  14. Economic targeting in modern warfare

    SciTech Connect (OSTI)

    Lambeth, B.S.; Lewis, K.N.

    1982-07-01T23:59:59.000Z

    Nuclear weapons and strategies for their use play a variety of roles in the defense and foreign policies of the United States and Soviet Union. Accordingly, both nations buy forces and prepare war plans for many purposes. Although it is perhaps the least likely contingency for which either country prepares, the scenario in which both sides launch more or less all-out attacks against their opponent's economic or urban-industrial target system often dominates public consideration of strategic policy issues. These kinds of strikes, generically termed countervalue attacks, are usually assumed to throw many thousands of nuclear weapons against cities and isolated facilities in order to destroy the adversary nation as an organized, functioning, and economically viable entity.

  15. Independent Oversight Targeted Review, Y-12 National Security...

    Office of Environmental Management (EM)

    Targeted Review, Y-12 National Security Complex - February 2012 Independent Oversight Targeted Review, Y-12 National Security Complex - February 2012 February 2012 Targeted Review...

  16. Explanations of FreedomCAR/DOE Hydrogen Storage Technical Targets...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Explanations of FreedomCARDOE Hydrogen Storage Technical Targets Explanations of FreedomCARDOE Hydrogen Storage Technical Targets Summary of FreedomCAR Targets and Basis for...

  17. The study of downstream targets and other characteristics of NTT

    E-Print Network [OSTI]

    Fung, Michelle W.

    2009-01-01T23:59:59.000Z

    SAN DIEGO The Study of Downstream Targets and OtherOF THE THESIS The Study of Downstream Targets and Othera number of putative downstream targets of NTT, including

  18. Table I: Technical Targets for Catalyst Coated Membranes (CCMs...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    I: Technical Targets for Catalyst Coated Membranes (CCMs): Automotive Table I: Technical Targets for Catalyst Coated Membranes (CCMs): Automotive Technical targets for fuel cell...

  19. Development of granular target for CADS

    E-Print Network [OSTI]

    McDonald, Kirk

    Exchanger 90K Max velocity of cold fluid 1.52m/s Wall Thickness of Heat Exchanger 1.75cm Flux of Gas inject Design goals: For CIADS, the target can accommodate 2.5MW=250MeV@10mA; the target system can update pipe can choose ~30-40 cm, then, the target would be design for >10MW. The heat removal of the window

  20. Moller Polarimetry with Atomic Hydrogen Targets

    SciTech Connect (OSTI)

    Chudakov, Eugene [Thomas Jefferson National Accelerator Facility, Newport News, VA (United States); Luppov, V. [University of Michigan Spin Physics Center, Ann Arbor, MI (United States)

    2012-06-01T23:59:59.000Z

    A proposal to use polarized atomic hydrogen gas as the target for electron beam polarimetry based on the Moller scattering is described. Such a gas, stored in an ultra-cold magnetic trap, would provide a target of practically 100\\% polarized electrons. It is conceivable to reach a $\\sim$0.3\\% systematic accuracy of the beam polarimetry with such a target. Feasibility studies for the CEBAF electron beam have been performed.

  1. Tensor Target Polarization at TRIUMF

    SciTech Connect (OSTI)

    Smith, G

    2014-10-27T23:59:59.000Z

    The first measurements of tensor observables in $\\pi \\vec{d}$ scattering experiments were performed in the mid-80's at TRIUMF, and later at SIN/PSI. The full suite of tensor observables accessible in $\\pi \\vec{d}$ elastic scattering were measured: $T_{20}$, $T_{21}$, and $T_{22}$. The vector analyzing power $iT_{11}$ was also measured. These results led to a better understanding of the three-body theory used to describe this reaction. %Some measurements were also made in the absorption and breakup channels. A direct measurement of the target tensor polarization was also made independent of the usual NMR techniques by exploiting the (nearly) model-independent result for the tensor analyzing power at 90$^\\circ _{cm}$ in the $\\pi \\vec{d} \\rightarrow 2p$ reaction. This method was also used to check efforts to enhance the tensor polarization by RF burning of the NMR spectrum. A brief description of the methods developed to measure and analyze these experiments is provided.

  2. Enterprise Assessments Targeted Review, Lawrence Livermore National...

    Broader source: Energy.gov (indexed) [DOE]

    February 2015 Targeted Review of the Safety-Class Room Ventilation Systems and Associated Final Filtration Stages, and Review of Federal Assurance Capability at the Lawrence...

  3. DOE Program/Targets and Workshop Objectives

    Broader source: Energy.gov (indexed) [DOE]

    Nancy Garland DOE Hydrogen Program Fuel Cell Operation at Sub- Freezing Temperatures DOE ProgramTargets and Workshop Objectives Sub-Freezing Temperature Effects on Fuel Cells...

  4. A method for comparing impacts with real targets to impacts onto the IAEA unyielding target

    SciTech Connect (OSTI)

    Ammerman, D. J.

    1991-01-01T23:59:59.000Z

    The severity of the IAEA accident conditions test requirement (IAEA 1990) of an impact onto an essentially unyielding target from a drop height of 9 meters encompasses a large fraction of all real world impacts. This is true, in part, because of the unyielding nature of the impact target. Impacts onto the unyielding target have severities equivalent to higher velocity impacts onto real targets which are not unyielding. The severity of impacts with yielding targets is decreased by the amount of the impact energy absorbed in damaging the target. In demonstrating the severity of the regulatory impact event it is advantageous to be able to relate this impact onto an essentially unyielding target to impacts with yielding targets.

  5. IFE Target Fabrication, Delivery, and Cost Estimates

    E-Print Network [OSTI]

    synergism but key differences that lead to specific technologies Heavy Ion Fusion Laser Fusion Z-Pinch IFE of this talk....... 1. IFE target technology builds upon the larger ICF program - Not starting from "zero" for IFE - Large effort for NIC fosters efficiency (e.g., foam shells) 2. The recent IFE target technology

  6. Radioactive Target Detection Using Wireless Sensor Network

    E-Print Network [OSTI]

    Zhang, Tonglin

    Chapter 31 Radioactive Target Detection Using Wireless Sensor Network Tonglin Zhang Abstract for wireless sensor network data to detect and locate a hidden nuclear target in a large study area. The method assumes multiple radiation detectors have been used as sensor nodes in a wireless sensor network

  7. TechnicalDesign Report, Second Target Station

    SciTech Connect (OSTI)

    Galambos, John D [ORNL; Anderson, David E [ORNL; Bechtol, D [HDR, Inc.; Bethea, Katie L [ORNL; Brown, N [Barge Waggoner Sumner & Cannon, Inc.; Carden, W. F. [Oak Ridge National Laboratory (ORNL); Chae, Steven M [ORNL; Clark, A. [Barge Waggoner Sumner & Cannon, Inc.; Counce, Deborah M [ORNL; Craft, K [Barge Waggoner Sumner & Cannon, Inc.; Crofford, Mark T [ORNL; Collins, Richard M [ORNL; Cousineau, Sarah M [ORNL; Curry, Douglas E [ORNL; Cutler, Roy I [ORNL; Dayton, Michael J [ORNL; Dean, Robert A [ORNL; Deibele, Craig E [ORNL; Doleans, Marc [ORNL; Dye, T. [HDR, Inc.; Eason, Bob H [ORNL; Eckroth, James A [ORNL; Fincrock, C [HDR, Inc.; Fritts, S. [Barge Waggoner Sumner & Cannon, Inc.; Gallmeier, Franz X [ORNL; Gawne, Ken R [ORNL; Hartman, Steven M [ORNL; Herwig, Kenneth W [ORNL; Hess, S. [HDR, Inc.; Holmes, Jeffrey A [ORNL; Horak, Charlie M [ORNL; Howell, Matthew P [ORNL; Iverson, Erik B [ORNL; Jacobs, Lorelei L [ORNL; Jones, Larry C [ORNL; Johnson, B. [HDR, Inc.; Johnson, S. [HDR, Inc.; Kasemir, Kay [ORNL; Kim, Sang-Ho [ORNL; Laughon, Gregory J [ORNL; Lu, W. [Oak Ridge National Laboratory (ORNL); Mahoney, Kelly L [ORNL; Mammosser, John [ORNL; McManamy, T. [McManamy Consulting, Inc.; Michilini, M. [HDR, Inc.; Middendorf, Mark E [ORNL; O'Neal, Ed [Oak Ridge National Laboratory (ORNL); Nemec, B. [Barge Waggoner Sumner & Cannon, Inc.; Peters, Roy Cecil [ORNL; Plum, Michael A [ORNL; Reagan, G. [Barge Waggoner Sumner & Cannon, Inc.; Remec, Igor [ORNL; Rennich, Mark J [ORNL; Riemer, Bernie [ORNL; Saethre, Robert B [ORNL; Schubert, James Phillip [ORNL; Shishlo, Andrei P [ORNL; Smith, C Craig [ORNL; Strong, William Herb [ORNL; Tallant, Kathie M [ORNL; Tennant, David Alan [ORNL; Thibadeau, Barbara M [ORNL; Trumble, S. [HDR, Inc.; Trotter, Steven M [ORNL; Wang, Z. [Institute of Modern Physics (IMP), Chinese Academy of Sciences; Webb, Steven B [ORNL; Williams, Derrick C [ORNL; White, Karen S [ORNL; Zhao, Jinkui [ORNL

    2015-01-01T23:59:59.000Z

    The Second Target Station (STS) is a proposed upgrade for SNS. It includes a doubling of the accelerator power and an additional instrument hall. The new instrument hall will recieve a 467 kW 10 Hz beam. The parameters and preliminary design aspects of the STS are presented for the accelerator, target systems, instrument hall, instruments and civil construction aspects.

  8. THE ROTATING TARGET FLOW TEST FACILITY

    E-Print Network [OSTI]

    McDonald, Kirk

    @idom.com) Fernando Sordo, ESS Bilbao Tom McManamy, ORNL/SNS #12;Status of the RTFT 4th HPTW of a RotaAng Target for ESS · In 2009 ESS Bilbao worked out a preliminary design for a rotaZng target for ESS. · Disc formed by un-clad tungsten bricks cooled

  9. Dissecting Apicoplast Targeting in the Malaria Parasite

    E-Print Network [OSTI]

    McFadden, Geoff

    and are only poorly understood. We extracted amino acid features from transit peptides that target proteins to the relict plastid (apicoplast) of malaria parasites. Based on these amino acid characteristics, we to be important for correct targeting. Plastid transit peptides mediate accurate tar- geting of many hundreds

  10. TARGET STATION INFRASTRUCTURE THE CNGS EXPERIENCE

    E-Print Network [OSTI]

    McDonald, Kirk

    of Aluminum Water cooled Current: 150kA (horn) ­ 180 kA (reflector) Pulse duration 7ms #12;Key elements Remote handling Remote station for radiation survey in the target chamber #12;CNGS Target Area I per cooling circuit 2007 run radiation effects on ventilation system electronics broken flexible stripline

  11. Delayed neutrons measurement at the MEGAPIE target

    E-Print Network [OSTI]

    Stefano Panebianco; Pavel Bokov; Diane Dore; Xavier Ledoux; Alain Letourneau; Aurelien Prevost; Danas Ridikas

    2007-05-25T23:59:59.000Z

    In the framework of the Neutronic and Nuclear Assessment Task Group of the MEGAPIE experiment we measured the delayed neutron (DN) flux at the top of the target. The measurement was proposed mainly for radioprotection purposes since the DN flux at the top of the target has been estimated to be of the same order of magnitude as the prompt neutron flux. Given the strong model-dependence of DN predictions, the measurement of DN contribution to the total neutron activity at the top of the target was thus desired. Moreover, this measurement is complementary to the DN experiments performed at PNPI (Gatchina) on solid lead and bismuth targets. The DN measurement at MEGAPIE was performed during the start-up phase of the target. In this paper we present a detailed description of the experimental setup and some preliminary results on decay spectra.

  12. Delayed neutrons measurement at the MEGAPIE target

    E-Print Network [OSTI]

    Panebianco, Stefano; Dore, Diane; Ledoux, Xavier; Letourneau, Alain; Prevost, Aurelien; Ridikas, Danas

    2007-01-01T23:59:59.000Z

    In the framework of the Neutronic and Nuclear Assessment Task Group of the MEGAPIE experiment we measured the delayed neutron (DN) flux at the top of the target. The measurement was proposed mainly for radioprotection purposes since the DN flux at the top of the target has been estimated to be of the same order of magnitude as the prompt neutron flux. Given the strong model-dependence of DN predictions, the measurement of DN contribution to the total neutron activity at the top of the target was thus desired. Moreover, this measurement is complementary to the DN experiments performed at PNPI (Gatchina) on solid lead and bismuth targets. The DN measurement at MEGAPIE was performed during the start-up phase of the target. In this paper we present a detailed description of the experimental setup and some preliminary results on decay spectra.

  13. The Jefferson Lab Frozen Spin Target

    SciTech Connect (OSTI)

    Christopher Keith, James Brock, Christopher Carlin, Sara Comer, David Kashy, Josephine McAndrew, David Meekins, Eugene Pasyuk, Joshua Pierce, Mikell Seely

    2012-08-01T23:59:59.000Z

    A frozen spin polarized target, constructed at Jefferson Lab for use inside a large acceptance spectrometer, is described. The target has been utilized for photoproduction measurements with polarized tagged photons of both longitudinal and circular polarization. Protons in TEMPO-doped butanol were dynamically polarized to approximately 90% outside the spectrometer at 5 T and 200-300 mK. Photoproduction data were acquired with the target inside the spectrometer at a frozen-spin temperature of approximately 30 mK with the polarization maintained by a thin, superconducting coil installed inside the target cryostat. A 0.56 T solenoid was used for longitudinal target polarization and a 0.50 T dipole for transverse polarization. Spin relaxation times as high as 4000 hours were observed. We also report polarization results for deuterated propanediol doped with the trityl radical OX063.

  14. Cooperative target convergence using multiple agents

    SciTech Connect (OSTI)

    Kwok, K.S.; Driessen, B.J.

    1997-10-01T23:59:59.000Z

    This work considers the problem of causing multiple (100`s) autonomous mobile robots to converge to a target and provides a follow-the-leader approach to the problem. Each robot has only a limited-range sensor for sending the target and also larger but also limited-range robot-to-robot communication capability. Because of the small amount of information available to the robots, a practical approach to improve convergence to the target is to have a robot follow the robot with the best quality of information. Specifically, each robot emits a signal that informs in-range robots what its status is. A robot has a status value of 0 if it is itself in range of the target. A robot has a status of 1 if it is not in range of the target but is in communication range of a robot that is in range of the target. A robot has a status of 2 if it is not in range of the target but is within range of another robot that has status 1, and so on. Of all the mobile robots that any given robot is in range of, it follows the one with the best status. The emergent behavior is the ant-like trails of robots following each other toward the target. If the robot is not in range of another robot that is either in range of the target or following another robot, the robot will assign-1 to its quality-of-information, and will execute an exhaustive search. The exhaustive search will continue until it encounters either the target or another robot with a nonnegative quality-of-information. The quality of information approach was extended to the case where each robot only has two-bit signals informing it of distance to in-range robots.

  15. RETRACTABLE HELIUM TRANSFER LINES FOR THE FLOATING FUSION Zhukovsky A., Garnier D.T.,* Fishman V., Lations R.

    E-Print Network [OSTI]

    CR06-45 RETRACTABLE HELIUM TRANSFER LINES FOR THE FLOATING FUSION MAGNET Zhukovsky A., Garnier D. When the magnet is low- ered, an inlet line, pre-cooled by liquid helium, is reinserted and re of helium at room temperature to 12.5 MPa. A lead-fiberglass high heat capacity radiation shield surrounds

  16. Micro-fabrication Techniques for Target Components

    SciTech Connect (OSTI)

    Miles, R; Hamilton, J; Crawford, J; Ratti, S; Trevino, J; Graff, T; Stockton, C; Harvey, C

    2008-06-10T23:59:59.000Z

    Micro-fabrication techniques, derived from the semi-conductor industry, can be used to make a variety of useful mechanical components for targets. A selection of these components including supporting cooling arms for prototype cryogenic inertial confinement fusion targets, stepped and graded density targets for materials dynamics experiments are described. Micro-fabrication enables cost-effective, simultaneous fabrication of multiple high-precision components with complex geometries. Micro-fabrication techniques such as thin-film deposition, photo-lithographic patterning and etch processes normally used in the semi-conductor manufacture industry, can be exploited to make useful mechanical target components. Micro-fabrication processes have in recent years been used to create a number of micro-electro-mechanical systems (MEMS) components such as pressure sensors, accelerometers, ink jet printer heads, microfluidics platforms and the like. These techniques consist primarily of deposition of thin films of material, photo-lithographic patterning and etching processes performed sequentially to produce three dimensional structures using essentially planar processes. While the planar technology can be limiting in terms of the possible geometries of the final product, advantages of using these techniques include the ability to make multiple complex structures simultaneously and cost-effectively. Target components fabricated using these techniques include the supporting cooling arms for cryogenic prototype fusion ignition targets, stepped targets for equation-of-state experiments, and graded density reservoirs for material strength experiments.

  17. Direct-illumination spherical-target experiments

    SciTech Connect (OSTI)

    Johnson, R.R.

    1982-01-01T23:59:59.000Z

    A set of spherical target experiments was designed to evaluate the effectiveness of three techniques for achieving higher convergence implosions. They are (1) cryogenically frozen fuel layers, (2) submicron wavelength laser light, and (3) temporally tailored pulse shapes. A second set of experiments provides information about energy transport by thermal and suprathermal electrons and uses multilayered targets as an integral component of the diagnostics. These results, in conjunction with existing laser-target coupling data, provide a more comprehensive test of our understanding of laser plasma interaction, energy transport, and hydrodynamic response of small scale spherical laser fusion experiments.

  18. Self-assessing target with automatic feedback

    DOE Patents [OSTI]

    Larkin, Stephen W.; Kramer, Robert L.

    2004-03-02T23:59:59.000Z

    A self assessing target with four quadrants and a method of use thereof. Each quadrant containing possible causes for why shots are going into that particular quadrant rather than the center mass of the target. Each possible cause is followed by a solution intended to help the marksman correct the problem causing the marksman to shoot in that particular area. In addition, the self assessing target contains possible causes for general shooting errors and solutions to the causes of the general shooting error. The automatic feedback with instant suggestions and corrections enables the shooter to improve their marksmanship.

  19. Targeting engineering synchronization in chaotic systems

    E-Print Network [OSTI]

    Sourav K. Bhowmick; Dibakar Ghosh

    2015-06-14T23:59:59.000Z

    A method of targeting engineering synchronization states in two identical and mismatch chaotic systems is explained in details. The method is proposed using linear feedback controller coupling for engineering synchronization such as mixed synchronization, linear and nonlinear generalized synchronization and targeting fixed point. The general form of coupling design to target any desire synchronization state under unidirectional coupling with the help of Lyapunov function stability theory is derived analytically. A scaling factor is introduced in the coupling definition to smooth control without any loss of synchrony. Numerical results are done on two mismatch Lorenz systems and two identical Sprott oscillators.

  20. ESO Imaging Survey: Finding Targets for VLT

    E-Print Network [OSTI]

    L. N. da Costa

    1998-09-16T23:59:59.000Z

    Data from the wide-angle, moderately deep ESO Imaging Survey have been used to produce target lists for the first year of the VLT. About 250 candidate clusters of galaxies have been identified from the I-band images covering $\\sim$ 17 square degrees. In addition, using the multicolor data available over an area of 1.3 square degrees over 300 potentially interesting point-sources have been selected. The color-selected targets include low-mass stars/brown dwarfs, white-dwarfs and quasars. Images, object catalogs and derived target lists are available from the world-wide web (http://www.eso.org/eis)

  1. Marketing Practices and Costs of Texas Egg Producer-Wholesalers.

    E-Print Network [OSTI]

    Shafer, Carl E.

    1964-01-01T23:59:59.000Z

    and the percentaie of eggs delivered on enterprise on Texas farms. The growth of popu- door-to-door consumer routes. Estimated process- lation and purchasing power and the current ing labor costs per case varied from $1.90 to ?; standing of Texas as a deficit... state in egg pro- cents between groups A and E; delivery labor duction all favor the Texas egg producer. To costs varied from 77 cents to 15 cents per case be take advantage of opportunities in the state tween groups A and G, respectively. market...

  2. Computing the apparent centroid of radar targets

    SciTech Connect (OSTI)

    Lee, C.E.

    1996-12-31T23:59:59.000Z

    A high-frequency multibounce radar scattering code was used as a simulation platform for demonstrating an algorithm to compute the ARC of specific radar targets. To illustrate this simulation process, several targets models were used. Simulation results for a sphere model were used to determine the errors of approximation associated with the simulation; verifying the process. The severity of glint induced tracking errors was also illustrated using a model of an F-15 aircraft. It was shown, in a deterministic manner, that the ARC of a target can fall well outside its physical extent. Finally, the apparent radar centroid simulation based on a ray casting procedure is well suited for use on most massively parallel computing platforms and could lead to the development of a near real-time radar tracking simulation for applications such as endgame fuzing, survivability, and vulnerability analyses using specific radar targets and fuze algorithms.

  3. Analysis of Climate Policy Targets under Uncertainty

    E-Print Network [OSTI]

    Jacoby, Henry D.

    Although policymaking in response to the climate change is essentially a challenge of risk management, most studies of the relation of emissions targets to desired climate outcomes are either deterministic or subject to a ...

  4. Beam Pulse Structure and Targets Roger Bennett

    E-Print Network [OSTI]

    McDonald, Kirk

    in a target. The shock wave travels through matter at the speed of sound, where E is Young's modulus of elasticity and is the density. E s = #12;The time taken for the wave to travel from the outer surface

  5. Targeting cancer metabolism: a therapeutic window opens

    E-Print Network [OSTI]

    Vander Heiden, Matthew G.

    Genetic events in cancer activate signalling pathways that alter cell metabolism. Clinical evidence has linked cell metabolism with cancer outcomes. Together, these observations have raised interest in targeting metabolic ...

  6. Webinar: Targeted Algal Biofuels and Bioproducts FOA

    Broader source: Energy.gov [DOE]

    The Energy Departments Bioenergy Technologies Office will present a live informational webcast on the Targeted Algal Biomass and Bioproducts Funding Opportunity (DE-FOA-0001162) on October 8, 2014...

  7. Computer-Aided Drug Target Search

    E-Print Network [OSTI]

    Chen, Yuzong

    Identification of the unknown targets of drugs, investigative drugs and herbal ingredients is an important task in drug discovery. It can potentially help in several aspects including: (1) determination of unknown therapeutic ...

  8. Statistical Modeling of Single Target Cell Encapsulation

    E-Print Network [OSTI]

    Moon, SangJun

    High throughput drop-on-demand systems for separation and encapsulation of individual target cells from heterogeneous mixtures of multiple cell types is an emerging method in biotechnology that has broad applications in ...

  9. Nanotechnology-mediated targeting of tumor angiogenesis

    E-Print Network [OSTI]

    Banerjee, Deboshri

    Abstract Angiogenesis is disregulated in many diseased states, most notably in cancer. An emerging strategy for the development of therapies targeting tumor-associated angiogenesis is to harness the potential of nanotechnology ...

  10. Method and apparatus for producing cryogenic targets

    DOE Patents [OSTI]

    Murphy, J.T.; Miller, J.R.

    1984-08-07T23:59:59.000Z

    An improved method and apparatus are given for producing cryogenic inertially driven fusion targets in the fast isothermal freezing (FIF) method. Improved coupling efficiency and greater availability of volume near the target for diagnostic purposes and for fusion driver beam propagation result. Other embodiments include a new electrical switch and a new explosive detonator, all embodiments making use of a purposeful heating by means of optical fibers. 6 figs.

  11. Method and apparatus for producing cryogenic targets

    DOE Patents [OSTI]

    Murphy, James T. (Los Alamos, NM); Miller, John R. (Penfield, NY)

    1984-01-01T23:59:59.000Z

    An improved method and apparatus are given for producing cryogenic inertially driven fusion targets in the fast isothermal freezing (FIF) method. Improved coupling efficiency and greater availability of volume near the target for diagnostic purposes and for fusion driver beam propagation result. Other embodiments include a new electrical switch and a new explosive detonator, all embodiments making use of a purposeful heating by means of optical fibers.

  12. Current status of the liquid lithium target

    E-Print Network [OSTI]

    McDonald, Kirk

    in target (mm) 252 x 125Maximum beam current (mA) ~1~10~100Beam spot on the target (cm2) >2 (peak)0.52.5Beam Water direction #12;15 Be Trap Heat Exchanger Cross Section Design to remove ~12 kW Lithium tank #12;Oil cycle Flexible tubes Oil pump Heat exchanger Oil chamber Inside the lab Outside the lab #12;Elect

  13. Creation of mixed beam from alloy target and couple of pure targets with laser

    SciTech Connect (OSTI)

    Ikeda, Shunsuke, E-mail: shunsuke.ikeda@riken.jp; Sekine, Megumi [Tokyo Institute of Technology, Yokohama, Kanagawa (Japan) [Tokyo Institute of Technology, Yokohama, Kanagawa (Japan); Riken, Wako, Saitama (Japan); Romanelli, Mark [Cornell University, Ithaca, New York 14850 (United States)] [Cornell University, Ithaca, New York 14850 (United States); Cinquegrani, David [University of Michigan, Ann Arbor, Michigan 48109 (United States)] [University of Michigan, Ann Arbor, Michigan 48109 (United States); Kumaki, Masafumi [Waseda University, Shinjuku, Tokyo (Japan)] [Waseda University, Shinjuku, Tokyo (Japan); Fuwa, Yasuhiro [Kyoto University, Uji, Kyoto (Japan)] [Kyoto University, Uji, Kyoto (Japan); Munemoto, Naoya; Horioka, Kazuhiko [Tokyo Institute of Technology, Yokohama, Kanagawa (Japan)] [Tokyo Institute of Technology, Yokohama, Kanagawa (Japan); Kanesue, Takeshi; Okamura, Masahiro [Brookhaven National Laboratory, Upton, New York 11973 (United States)] [Brookhaven National Laboratory, Upton, New York 11973 (United States); Jin, Qianyu [Institute of Modern Physics, Lanzhou, Gansu (China)] [Institute of Modern Physics, Lanzhou, Gansu (China)

    2014-02-15T23:59:59.000Z

    To create mixed species ion beam with laser pulses, we investigated charge state distributions of plasma formed from both Al-Fe alloy targets and pure Al and Fe targets placed close together. With two targets, we observed that the two kinds of atoms were mixed when the interval of two laser pulses was large enough (40 ?s). On the other hand, when the interval was 0.0 ?s, we observed fewer Fe ions and they did not mix well with the Al ions. The two species were mixed well in the plasma from the alloy target. Furthermore, we observed that specific charge states of Fe ions increased. From the results, it was determined that we can use two pure targets to mix two species whose difference of the drift velocity is large. On the other hand, we must use an alloy target when the drift velocities of the species are close.

  14. Fast ignition of inertial confinement fusion targets

    SciTech Connect (OSTI)

    Gus'kov, S. Yu., E-mail: guskov@sci.lebedev.ru [Russian Academy of Sciences, Lebedev Physical Institute (Russian Federation)

    2013-01-15T23:59:59.000Z

    Results of studies on fast ignition of inertial confinement fusion (ICF) targets are reviewed. The aspects of the fast ignition concept, which consists in the separation of the processes of target ignition and compression due to the synchronized action of different energy drivers, are considered. Criteria for the compression ratio and heating rate of a fast ignition target, the energy balance, and the thermonuclear gain are discussed. The results of experimental and theoretical studies of the heating of a compressed target by various types of igniting drivers, namely, beams of fast electrons and light ions produced under the action of a petawatt laser pulse on the target, a heavy-ion beam generated in the accelerator, an X-ray pulse, and a hydrodynamic flow of laser-accelerated matter, are analyzed. Requirements to the igniting-driver parameters that depend on the fast ignition criteria under the conditions of specific target heating mechanisms, as well as possibilities of practical implementation of these requirements, are discussed. The experimental programs of various laboratories and the prospects of practical implementation of fast ignition of ICF targets are reviewed. To date, fast ignition is the most promising method for decreasing the ignition energy and increasing the thermonuclear gain of an ICF plasma. A large number of publications have been devoted to investigations of this method and adjacent problems of the physics of igniting drivers and their interaction with plasma. This review presents results of only some of these studies that, in the author's opinion, allow one to discuss in detail the main physical aspects of the fast ignition concept and understand the current state and prospects of studies in this direction.

  15. Tracking Multiple Targets Using Binary Decisions from Wireless Sensor Networks

    E-Print Network [OSTI]

    Michailidis, George

    Tracking Multiple Targets Using Binary Decisions from Wireless Sensor Networks Natallia Katenka- tions. 1 #12;Keywords: wireless sensor networks, binary data, target tracking, multiple targets, penal- ized maximum likelihood 1 Introduction and Problem Motivation Wireless Sensor Networks (WSN) have

  16. The CNGS Target Station Presented by L.Bruno

    E-Print Network [OSTI]

    McDonald, Kirk

    sealed system filled with 0.5 bar of He. The tube has annular fins to enhance convective heat transfer enclosure Inlet target Inlet fixed shielding Outlet Beam #12;The target Assembly The CNGS Target Station as

  17. Divertor target for magnetic containment device

    DOE Patents [OSTI]

    Luzzi, Jr., Theodore E. (Garden City, NY)

    1982-01-01T23:59:59.000Z

    In a plasma containment device of a type having superconducting field coils for magnetically shaping the plasma into approximately the form of a torus, an improved divertor target for removing impurities from a "scrape off" region of the plasma comprises an array of water cooled swirl tubes onto which the scrape off flux is impinged. Impurities reflected from the divertor target are removed from the target region by a conventional vacuum getter system. The swirl tubes are oriented and spaced apart within the divertor region relative to the incident angle of the scrape off flux to cause only one side of each tube to be exposed to the flux to increase the burnout rating of the target. The divertor target plane is oriented relative to the plane of the path of the scrape off flux such that the maximum heat flux onto a swirl tube is less than the tube design flux. The containment device is used to contain the plasma of a tokamak fusion reactor and is applicable to other long pulse plasma containment systems.

  18. Neutronic Characterization of the Megapie Target

    E-Print Network [OSTI]

    Stefano Panebianco; Olivier Bringer; Pavel Bokov; Sebastien Chabod; Frederic Chartier; Emmeric Dupont; Diane Dore; Xavier Ledoux; Alain Letourneau; Ludovic Oriol; Aurelien Prevost; Danas Ridikas; Jean-Christian Toussaint

    2007-10-31T23:59:59.000Z

    The MEGAPIE project is one of the key experiments towards the feasibility of Accelerator Driven Systems. On-line operation and post-irradiation analysis will provide the scientific community with unique data on the behavior of a liquid spallation target under realistic irradiation conditions. A good neutronics performance of such a target is of primary importance towards an intense neutron source, where an extended liquid metal loop requires some dedicated verifications related to the delayed neutron activity of the irradiated PbBi. In this paper we report on the experimental characterization of the MEGAPIE neutronics in terms of the prompt neutron (PN) flux inside the target and the delayed neutron (DN) flux on the top of it. For the PN measurements, a complex detector, made of 8 microscopic fission chambers, has been built and installed in the central part of the target to measure the absolute neutron flux and its spatial distribution. Moreover, integral information on the neutron energy distribution as a function of the position along the beam axis could be extracted, providing integral constraints on the neutron production models implemented in transport codes such as MCNPX. For the DN measurement, we used a standard 3He counter and we acquired data during the start-up phase of the target irradiation in order to take sufficient statistics at variable beam power. Experimental results obtained on the PN flux characteristics and their comparison with MCNPX simulations are presented, together with a preliminary analysis of the DN decay time spectrum.

  19. Enterprise Assessments Targeted Review, Work Planning and Control...

    Energy Savers [EERE]

    Assessments Targeted Review, Work Planning and Control at the Hanford Tank Farms - April 2015 Enterprise Assessments Targeted Review, Work Planning and Control at the Hanford Tank...

  20. ascl1 target genes: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    for postgenomic analysis of mammalian gene function is gene targeting McConnell, Susan 2 Infrared lasermediated gene induction in targeted Chemistry Websites Summary: a heat shock...

  1. abolishes gene targeting: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    for postgenomic analysis of mammalian gene function is gene targeting McConnell, Susan 2 Infrared lasermediated gene induction in targeted Chemistry Websites Summary: a heat shock...

  2. EPA-GHG Inventory Targeted Data Collection Strategies and Software...

    Open Energy Info (EERE)

    EPA-GHG Inventory Targeted Data Collection Strategies and Software Tools (Redirected from US EPA GHG Inventory Targeted Data Collection Strategies and Software Tools) Jump to:...

  3. Jupiter Laser Facility Target Fab Request Requester: Date...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Sketches: Jupiter Laser Facility Target Fab Request Requester: Date Requested: Phone or E-Mail: Date Required: Target Name: Reference : Laser System: Project: Task:...

  4. Enterprise Assessments Targeted Review,Y-12 National Security...

    Office of Environmental Management (EM)

    Y-12 National Security Complex - March 2015 Enterprise Assessments Targeted Review,Y-12 National Security Complex - March 2015 March 2015 Targeted Review of Work Planning and...

  5. Structural genomics of infectious disease drug targets: the SSGCID...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of infectious disease drug targets: the SSGCID. Structural genomics of infectious disease drug targets: the SSGCID. Abstract: The NIAID-funded SSGCID is a consortium established to...

  6. Antibody-independent Targeted Quantification of TMPRSS2-ERG Fusion...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    independent Targeted Quantification of TMPRSS2-ERG Fusion Protein Products in Prostate Cancer. Antibody-independent Targeted Quantification of TMPRSS2-ERG Fusion Protein Products...

  7. Fluorescent Multiblock ?-Conjugated Polymer Nanoparticles for In Vivo Tumor Targeting

    E-Print Network [OSTI]

    Ahmed, Eilaf

    Highly fluorescent multiblock conjugated polymer nanoparticles with folic acid surface ligands are highly effective for bioimaging and in vivo tumor targeting. The targeted nanoparticles were preferentially localized in ...

  8. Status of T2K Target 2nd Oxford-Princeton High-Power Target Workshop

    E-Print Network [OSTI]

    McDonald, Kirk

    Graphite (ToyoTanso IG-43) Current Target Design Helium cooling Graphite to titanium diffusion bond 47.0 46-Power Target Workshop Mike Fitton IG43 Graphite diffusion bonded into Ti-6Al-4V titanium, Special Techniques Group at UKAEA Culham Diffusion Bond + Graphite-Graphite bonding test Aluminium intermediate layer

  9. What is TARGET? The Transnational Applied Research in Gender Equity Training (TARGET) project focuses on the

    E-Print Network [OSTI]

    Sheridan, Jennifer

    and strategies in the developing world. Articles have been culled from major academic search engines and have and present research results in academic and applied contexts What are TARGET Activities? Database Preparation TARGET participants have surveyed academic databases and are developing a searchable bibliography

  10. Linear and angular retroreflecting interferometric alignment target

    DOE Patents [OSTI]

    Maxey, L. Curtis (Powell, TN)

    2001-01-01T23:59:59.000Z

    The present invention provides a method and apparatus for measuring both the linear displacement and angular displacement of an object using a linear interferometer system and an optical target comprising a lens, a reflective surface and a retroreflector. The lens, reflecting surface and retroreflector are specifically aligned and fixed in optical connection with one another, creating a single optical target which moves as a unit that provides multi-axis displacement information for the object with which it is associated. This displacement information is useful in many applications including machine tool control systems and laser tracker systems, among others.

  11. Neutron single target spin asymmetries in SIDIS

    SciTech Connect (OSTI)

    Evaristo Cisbani

    2010-04-01T23:59:59.000Z

    The experiment E06-010 in Hall A at Jefferson Lab took data between November 2008 and February 2009 to directly measure, for the first time, the pion (and kaon) single "neutron" target-spin asymmetry (SSA) in semi-inclusive DIS from a polarized 3He target. Collins, Sivers (and Pretzelosity) neutron asymmetries are going to be extracted from the measured SSA. Details of the experiment are described together with the preliminary results of the ongoing analysis. Near future Hall A experiments on transverse nucleon spin structure are shorty reviewed.

  12. Prototyping of the ILC Baseline Positron Target

    SciTech Connect (OSTI)

    Gronberg, J; Brooksby, C; Piggott, T; Abbott, R; Javedani, J; Cook, E

    2012-02-29T23:59:59.000Z

    The ILC positron system uses novel helical undulators to create a powerful photon beam from the main electron beam. This beam is passed through a titanium target to convert it into electron-positron pairs. The target is constructed as a 1 m diameter wheel spinning at 2000 RPM to smear the 1 ms ILC pulse train over 10 cm. A pulsed flux concentrating magnet is used to increase the positron capture efficiency. It is cooled to liquid nitrogen temperatures to maximize the flatness of the magnetic field over the 1 ms ILC pulse train. We report on prototyping effort on this system.

  13. ALT-3 Target & CMU Version 4

    SciTech Connect (OSTI)

    Griego, Jeffrey R [Los Alamos National Laboratory; Atchison, Walter L. [Los Alamos National Laboratory; Holtkamp, David [Los Alamos National Laboratory; Oro, David M. [Los Alamos National Laboratory; Reinovsky, Robert E. [Los Alamos National Laboratory; Rousculp, Christopher L. [Los Alamos National Laboratory; Tabaka, Leonard J. [Los Alamos National Laboratory

    2012-06-11T23:59:59.000Z

    The third Advance Liner Technology (ALT-3) experiment is the next in a long tradition of collaborations between LANL and RFNC/VNIIEF in high-explosive pulsed-power. Here a VNIIEF provided Disk Explosive Magnetic Generator (DEMG) will drive a LANL provided experimental load and diagnostic package. The objective of the experiment is to explore the use of a cylindrical liner-ontarget in tera-Pascal equation of state measurement. This presentation will discuss version 4 of the experimental target and central measuring unit (CMU) along with R & D already performed in fabrication of the target.

  14. Accounting for population variation in targeted proteomics

    SciTech Connect (OSTI)

    Fujimoto, Grant M.; Monroe, Matthew E.; Rodriguez, Larissa M.; Wu, Chaochao; MacLean, Brendan; Smith, Richard D.; MacCoss, Michael; Payne, Samuel H.

    2014-01-03T23:59:59.000Z

    Individual proteomes typically differ from the reference human proteome at ~10,000 single amino acid variants. When viewed at the population scale, this individual variation results in a wide variety of protein sequences. In targeted proteomics experiments, such variability would confound accurate protein quantification. To facilitate researchers in identifying target peptides with high variability within the human population we have created the Population Variation plug-in for Skyline, which provides easy access to the polymorphisms stored in dbSNP. Given a set of peptides, the tool reports minor allele frequency for common polymorphisms. We highlight the importance of considering genetic variation by applying the tool to public datasets.

  15. Recent developments in zinc oxide target chemistry

    SciTech Connect (OSTI)

    Heaton, R.C.; Taylor, W.A.; Phillips, D.R.; Jamriska, D.J. Sr.; Garcia, J.B.

    1994-04-01T23:59:59.000Z

    Zinc oxide targets irradiated with high energy protons at the Los Alamos Meson Physics Facility (LAMPF) contain a number of radioactive spallation products in quantities large enough to warrant recovery. This paper describes methods for recovering {sup 7}Be, {sup 46}Sc, and {sup 48}V from such targets and offers suggestions on possible ways to recover additional isotopes. The proposed methods are based on traditional precipitation and ion exchange techniques, are readily adaptable to hot cell use, and produce no hazardous waste components. The products are obtained in moderate to high yields and have excellent radiopurity.

  16. Influence of lateral target size on hot electron production and electromagnetic pulse emission from laser-irradiated metallic targets

    SciTech Connect (OSTI)

    Chen Ziyu; Li Jianfeng; Yu Yong; Li Xiaoya; Peng Qixian; Zhu Wenjun [National Key Laboratory of Shock Wave and Detonation Physics, Institute of Fluid Physics, China Academy of Engineering Physics, Mianyang, Sichuan 621900 (China); Wang Jiaxiang [State Key Laboratory of Precision Spectroscopy, East China Normal University, Shanghai 200062 (China)

    2012-11-15T23:59:59.000Z

    The influences of lateral target size on hot electron production and electromagnetic pulse emission from laser interaction with metallic targets have been investigated. Particle-in-cell simulations at high laser intensities show that the yield of hot electrons tends to increase with lateral target size, because the larger surface area reduces the electrostatic field on the target, owing to its expansion along the target surface. At lower laser intensities and longer time scales, experimental data characterizing electromagnetic pulse emission as a function of lateral target size also show target-size effects. Charge separation and a larger target tending to have a lower target potential have both been observed. The increase in radiation strength and downshift in radiation frequency with increasing lateral target size can be interpreted using a simple model of the electrical capacity of the target.

  17. High density laser-driven target

    DOE Patents [OSTI]

    Lindl, John D. (San Ramon, CA)

    1981-01-01T23:59:59.000Z

    A high density target for implosion by laser energy composed of a central quantity of fuel surrounded by a high-Z pusher shell with a low-Z ablator-pusher shell spaced therefrom forming a region filled with low-density material.

  18. Liquid targets for isotope production Jerry Nolen

    E-Print Network [OSTI]

    McDonald, Kirk

    Li) 4 High-Q 8B and 8Li will not be considered for the time being We will not explore the lowW E-beam-on-Target Test at ANL MCNPX : for RIA, 200-kW uranium beam on Li peak energy deposition = 2

  19. MERcury Intense Target (MERIT) Van Graves, ORNL

    E-Print Network [OSTI]

    McDonald, Kirk

    OF ENERGY Airline Hydraulics 28 Oct 2005 Hg System Schematic Double Window (2) Primary Containment SecondaryMERcury Intense Target (MERIT) Overview Van Graves, ORNL Syringe Procurement Kickoff Meeting Airline Hydraulics Bensalem, PA Oct 28, 2005 #12;2 OAK RIDGE NATIONAL LABORATORY U. S. DEPARTMENT

  20. Autonomous Airborne Geomagnetic Surveying and Target Identification

    E-Print Network [OSTI]

    Washington at Seattle, University of

    Positioning System (GPS) technology, and sensors (video and infrared cameras, magnetometers) coupled and identification of magnetic anomalies are evaluated. A combination of a particle filter and a neural network Airspeed w Weight on particle x State of agent with respect to target z Sensor measurement Subscript t Time

  1. Autonomous Airborne Geomagnetic Surveying and Target Identification

    E-Print Network [OSTI]

    Lum, Christopher

    in miniaturized electronics, Global Positioning System (GPS) technology, and sensors (video and infrared cameras and identification of magnetic anomalies are evaluated. A combination of a particle filter and a neural network Airspeed w Weight on particle x State of agent with respect to target z Sensor measurement Subscript t Time

  2. Titanium Target Module V.B. Graves

    E-Print Network [OSTI]

    McDonald, Kirk

    , reducer also Titanium #12;7 OAK RIDGE NATIONAL LABORATORY U. S. DEPARTMENT OF ENERGY MERIT VRVS Mtg 1 FebTitanium Target Module Changes V.B. Graves P.T. Spampinato T.A. Gabriel MERIT VRVS Meeting February 1, 2006 #12;2 OAK RIDGE NATIONAL LABORATORY U. S. DEPARTMENT OF ENERGY MERIT VRVS Mtg 1 Feb 2006

  3. High Power Target Design and Operational Considerations

    E-Print Network [OSTI]

    McDonald, Kirk

    remote handling is a major driving requirement). #12;3 Managed by UT-Battelle for the U.S. Department Issues · Steady state power handling. ­ Cooling of target/enclosure window ­ wettability. ­ Hot spots systems: ­ Mercury loop operation. ­ Remote handling. · Nuclear data. #12;4 Managed by UT

  4. Manufacturing complex silica aerogel target components

    SciTech Connect (OSTI)

    Defriend Obrey, Kimberly Ann [Los Alamos National Laboratory; Day, Robert D [Los Alamos National Laboratory; Espinoza, Brent F [Los Alamos National Laboratory; Hatch, Doug [Los Alamos National Laboratory; Patterson, Brian M [Los Alamos National Laboratory; Feng, Shihai [Los Alamos National Laboratory

    2008-01-01T23:59:59.000Z

    Aerogel is a material used in numerous components in High Energy Density Physics targets. In the past these components were molded into the proper shapes. Artifacts left in the parts from the molding process, such as contour irregularities from shrinkage and density gradients caused by the skin, have caused LANL to pursue machining as a way to make the components.

  5. UKNF 12 January 2005 Target Studies

    E-Print Network [OSTI]

    McDonald, Kirk

    . #12;to vacuum pump heater test wire insulators to pulsed power supply to pulsed power supply water in the target. So a new plan is needed #12;The New Plan 1. Pulsed ohmic-heating of wires replicates beam-DYNA. 4.The VISAR can be made in Laser Division at RAL. 5. Calculate the pion yield, beam heating

  6. Target Options for a Neutrino Factory

    E-Print Network [OSTI]

    McDonald, Kirk

    ;Fluidised tungsten powder: broadly compatible with baseline 1 2 3 4 Rig contains 100 kg Tungsten IncreasingDriverPressure #12;Schematic of implementation as a Neutrino Factory target Tungsten powder hopper configurations possible #12;Pion+muon production for variable length 50% material fraction W vs 100% Hg rbeam

  7. Improving Targeted Radionuclide Therapy Using Nuclear Nanotechnology

    E-Print Network [OSTI]

    Evans, Jordan Andrew

    2013-05-03T23:59:59.000Z

    IMPROVING TARGETED RADIONUCLIDE THERAPY USING NUCLEAR NANOTECHNOLOGY A Thesis by JORDAN ANDREW EVANS Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements for the degree... of Nanotechnology ................................................. 4 1.3 Paradigm Shift - Improving TRT Using Nuclear Nanotechnology .......... 8 1.4 Cancer Cell Line Investigated in This Study .......................................... 14 1.5 Nano...

  8. On the large COMPASS polarized deuteron target , N. Doshitac

    E-Print Network [OSTI]

    Dutz, Hartmut

    On the large COMPASS polarized deuteron target J. Balla , G. Baumb , N. Doshitac , M. Finger, Jr target in the COMPASS experiment at CERN since 2001. To achieve high luminosities a large solid polarized target is used. The COMPASS polarized target consists of a high cooling power 3 He/4 He dilution refriger

  9. Energy-Efficient Target Coverage in Wireless Sensor Networks

    E-Print Network [OSTI]

    Cardei, Mihaela

    successively. Only the sensors from the current active set are responsible for monitoring all targets

  10. Robust Target Localization from Binary Decisions in Wireless Sensor Networks

    E-Print Network [OSTI]

    Michailidis, George

    Robust Target Localization from Binary Decisions in Wireless Sensor Networks Natallia Katenka Wireless sensor networks (WSN) are becoming an important tool in a variety of tasks, including mon- itoring targets and localizing multiple targets are also considered. Keywords: wireless sensor network, target

  11. 1. Introduction 2. Apicoplast as a drug target

    E-Print Network [OSTI]

    McFadden, Geoff

    1. Introduction 2. Apicoplast as a drug target 3. Conclusion 4. Expert opinion Review Targeting an excellent drug target. Areas covered: This review focuses on the biological role of the apicoplast in the erythrocytic life cycle and what that reveals about existing drug targets. We also discuss the future

  12. In silico target prediction: identification of on- and off-targets for crop protection agents

    E-Print Network [OSTI]

    Chiddarwar, Rucha K; Bender, Andreas; Rohrer, Sebastian

    2013-03-22T23:59:59.000Z

    mining purposes. Of relatively recent relevance for the field of agrochemicals is the area of che- minformatics where novel applications range from lead identification to target prediction [2]. Agrochemicals, just as other bioactive compounds, in many... -of- action analysis or the anticipation of adverse effects of agrochemical products. In this spirit, the current project aims at a faster elucidation of agrochemical target proteins based on chemical structures. Using publicly available data as an input...

  13. Environmental management system objectives & targets results summary :

    SciTech Connect (OSTI)

    Vetter, Douglas Walter

    2014-04-01T23:59:59.000Z

    Sandia National Laboratories/New Mexicos (SNL/NM) Environmental Management System is the integrated approach for members of the workforce to identify and manage environmental risks. Each Fiscal Year (FY) SNL/NM performs an analysis to identify environmental aspects, and the environmental programs associated with them are charged with the task of routinely monitoring and measuring the objectives and targets that are established to mitigate potential impacts of SNL/NMs operations on the environment. An annual summary of the results achieved towards meeting established Sandia Corporation and SNL/NM Site-specific objectives and targets provides a connection to, and rational for, annually revised environmental aspects. The purpose of this document is to summarize the results achieved and documented in FY2013.

  14. Fixed target experiments at the Fermilab Tevatron

    E-Print Network [OSTI]

    Gaston Gutierrez; Marco A. Reyes

    2014-09-29T23:59:59.000Z

    This paper presents a review of the study of Exclusive Central Production at a Center of Mass energy of $\\sqrt{s}=40$ GeV at the Fermilab Fixed Target program. In all reactions reviewed in this paper, protons with an energy of 800 GeV were extracted from the Tevatron accelerator at Fermilab and directed to a Liquid Hydrogen target. The states reviewed include $\\pi^+\\pi^-$, $K^0_s K^0_s$, $ K^0_sK^\\pm\\pi^\\mp$, $\\phi\\phi$ and $D^{*\\pm}$. Partial Wave Analysis results will be presented on the light states but only the cross section will be reviewed in the diffractive production of $D^{*\\pm}$

  15. Recovery of niobium from irradiated targets

    DOE Patents [OSTI]

    Phillips, Dennis R. (Los Alamos, NM); Jamriska, Sr., David J. (Los Alamos, NM); Hamilton, Virginia T. (Los Alamos, NM)

    1994-01-01T23:59:59.000Z

    A process for selective separation of niobium from proton irradiated molybdenum targets is provided and includes dissolving the molybdenum target in a hydrogen peroxide solution to form a first ion-containing solution, contacting the first ion-containing solution with a cationic resin whereby ions selected form the group consisting of molybdenum, biobium, technetium, selenium, vanadium, arsenic, germanium, zirconium and rubidium remain in a second ion-containing solution while ions selected from the group consisting of rubidium, zinc, beryllium, cobalt, iron, manganese, chromium, strontium, yttrium and zirconium are selectively adsorbed by the cationic resin; adjusting the pH of the second ion-containing solution to within a range of from about 5.0 to about 6.0; contacting the pH adjusting second ion-containing solution with a dextran-based material for a time to selectively separate niobium from the solution and recovering the niobium from the dextran-based material.

  16. Flow mapping for an ESS horizontal target

    SciTech Connect (OSTI)

    Takeda, Y.; Kikura, H.; Taishi, T. [Paul Scherrer Institute, Villigen (Switzerland)

    1997-12-01T23:59:59.000Z

    In the target of the European spallation neutron source (ESS), the beam line is horizontal and the mercury is fully forced by a pump in a parallel channel geometry. The top front of the assembly is a hemicylindrical wall, where the beam enters and is thus called a window. The main body is partitioned by a horizontal separation plate into the upper and the lower flow channels. The target liquid flows in the lower channel to the window region, turns there, and flows out in the upper channel. A thermal-hydraulic study is under way to investigate the general behavior of the flow in this configuration. The present experimental work is the first step of an effort to validate computer codes. The model used in this investigation is two-dimensional and uses water.

  17. Magnetized Target Fusion Collaboration. Final report

    SciTech Connect (OSTI)

    John Slough

    2012-04-18T23:59:59.000Z

    Nuclear fusion has the potential to satisfy the prodigious power that the world will demand in the future, but it has yet to be harnessed as a practical energy source. The entry of fusion as a viable, competitive source of power has been stymied by the challenge of finding an economical way to provide for the confinement and heating of the plasma fuel. It is the contention here that a simpler path to fusion can be achieved by creating fusion conditions in a different regime at small scale (~ a few cm). One such program now under study, referred to as Magnetized Target Fusion (MTF), is directed at obtaining fusion in this high energy density regime by rapidly compressing a compact toroidal plasmoid commonly referred to as a Field Reversed Configuration (FRC). To make fusion practical at this smaller scale, an efficient method for compressing the FRC to fusion gain conditions is required. In one variant of MTF a conducting metal shell is imploded electrically. This radially compresses and heats the FRC plasmoid to fusion conditions. The closed magnetic field in the target plasmoid suppresses the thermal transport to the confining shell, thus lowering the imploding power needed to compress the target. The undertaking described in this report was to provide a suitable target FRC, as well as a simple and robust method for inserting and stopping the FRC within the imploding liner. The FRC must also survive during the time it takes for the metal liner to compress the FRC target. The initial work at the UW was focused on developing adequate preionization and flux trapping that were found to be essential in past experiments for obtaining the density, flux and most critically, FRC lifetime required for MTF. The timescale for testing and development of such a source can be rapidly accelerated by taking advantage of a new facility funded by the Department of Energy. At this facility, two inductive plasma accelerators (IPA) were constructed and tested. Recent experiments with these IPAs have demonstrated the ability to rapidly form, accelerate and merge two hypervelocity FRCs into a compression chamber. The resultant FRC that was formed was hot (T{sub ion} ~ 400 eV), stationary, and stable with a configuration lifetime several times that necessary for the MTF liner experiments. The accelerator length was less than 1 meter, and the time from the initiation of formation to the establishment of the final equilibrium was less than 10 microseconds. With some modification, each accelerator can be made capable of producing FRCs suitable for the production of the target plasma for the MTF liner experiment. Based on the initial FRC merging/compression results, the design and methodology for an experimental realization of the target plasma for the MTF liner experiment can now be defined. The construction and testing of the key components for the formation of the target plasma at the Air Force Research Laboratory (AFRL) will be performed on the IPA experiment, now at MSNW. A high density FRC plasmoid will be formed and accelerated out of each IPA into a merging/compression chamber similar to the imploding liner at AFRL. The properties of the resultant FRC plasma (size, temperature, density, flux, lifetime) will be obtained. The process will be optimized, and a final design for implementation at AFRL will be carried out. When implemented at AFRL it is anticipated that the colliding/merging FRCs will then be compressed by the liner. In this manner it is hoped that ultimately a plasma with ion temperatures reaching the 10 keV range and fusion gain near unity can be obtained.

  18. Synthetic LDL as targeted drug delivery vehicle

    DOE Patents [OSTI]

    Forte, Trudy M. (Berkeley, CA); Nikanjam, Mina (Richmond, CA)

    2012-08-28T23:59:59.000Z

    The present invention provides a synthetic LDL nanoparticle comprising a lipid moiety and a synthetic chimeric peptide so as to be capable of binding the LDL receptor. The synthetic LDL nanoparticle of the present invention is capable of incorporating and targeting therapeutics to cells expressing the LDL receptor for diseases associated with the expression of the LDL receptor such as central nervous system diseases. The invention further provides methods of using such synthetic LDL nanoparticles.

  19. Designing high power targets with computational fluid dynamics (CFD)

    SciTech Connect (OSTI)

    Covrig, S. D. [Thomas Jefferson National Laboratory, Newport News, VA 23606 (United States)

    2013-11-07T23:59:59.000Z

    High power liquid hydrogen (LH2) targets, up to 850 W, have been widely used at Jefferson Lab for the 6 GeV physics program. The typical luminosity loss of a 20 cm long LH2 target was 20% for a beam current of 100 ?A rastered on a square of side 2 mm on the target. The 35 cm long, 2500 W LH2 target for the Qweak experiment had a luminosity loss of 0.8% at 180 ?A beam rastered on a square of side 4 mm at the target. The Qweak target was the highest power liquid hydrogen target in the world and with the lowest noise figure. The Qweak target was the first one designed with CFD at Jefferson Lab. A CFD facility is being established at Jefferson Lab to design, build and test a new generation of low noise high power targets.

  20. A comparison of regulatory impacts to real target impacts

    SciTech Connect (OSTI)

    Ammerman, D.J.

    1998-05-01T23:59:59.000Z

    The purpose of this paper is to discuss the relative severity of regulatory impacts onto an essentially rigid target to impacts at higher velocities onto real targets. For impacts onto the essentially rigid target all of the kinetic energy of the package is absorbed by deformation of the package. For impacts onto real targets the kinetic energy is absorbed by deformation of the target as well as by deformation of the package. The amount of kinetic energy absorbed by the target does not increase the severity of the impact.

  1. Fuel Target Implosion in Ion beam Inertial Confinement Fusion

    E-Print Network [OSTI]

    Kawata, Shigeo

    2015-01-01T23:59:59.000Z

    The numerical results for the fuel target implosion are presented in order to clarify the target physics in ion beam inertial fusion. The numerical analyses are performed for a direct-driven ion beam target. In the paper the following issues are studied: the beam obliquely incidence on the target surface, the plasma effect on the beam-stopping power, the beam particle energy, the beam time duration, the target radius, the beam input energy and the non-uniformity effect on the fuel target performance. In this paper the beam ions are protons.

  2. Targeting the Poor: Evidence from a Field Experiment in Indonesia

    E-Print Network [OSTI]

    Alatas, Vivi

    This paper reports an experiment in 640 Indonesian villages on three approaches to target the poor: proxy means tests (PMT), where assets are used to predict consumption; community targeting, where villagers rank everyone ...

  3. An Efficient Message Passing Algorithm for Multi-Target Tracking

    E-Print Network [OSTI]

    Chen, Zhexu (Michael)

    We propose a new approach for multi-sensor multi-target tracking by constructing statistical models on graphs with continuous-valued nodes for target states and discrete-valued nodes for data association hypotheses. These ...

  4. Unscented Kalman Filters for Multiple Target Tracking with Symmetric Measurement

    E-Print Network [OSTI]

    Lanterman, Aaron

    1 Unscented Kalman Filters for Multiple Target Tracking with Symmetric Measurement Equations measurement equation approach to multiple target tracking is revisited using unscented Kalman and particle measurement equation implementation relying upon an extended Kalman filter. Counterintuitive results

  5. A Study of Scotland's Emission and Energy Targets

    E-Print Network [OSTI]

    Reeve, Rebecca

    2011-11-24T23:59:59.000Z

    and technologically achievable, the wide range of barriers and carbon abatement uncertainty of certain policy measures makes meeting all but renewable heat target fairly remote. It was also discussed that although meeting Scotlands emissions targets would have a...

  6. A method for relating impacts with yielding and unyielding targets

    SciTech Connect (OSTI)

    Ammerman, D.J.

    1991-01-01T23:59:59.000Z

    The public has questioned the severity of the regulatory 9 meter drop onto an unyielding target required for Type B radioactive material shipping packages since this drop height results in an impact velocity of only 13.3 m/s (30 MPH). It is the unyielding nature of the regulatory target which makes the 9 meter drop so severe. In this paper a method for relating higher velocity impacts with yielding targets to impacts onto an unyielding target is developed. The severity of impacts with yielding targets is decreased by the amount of the impact energy absorbed in damaging the target. There have been previous attempts to correlate impacts with yielding targets to lower velocity impacts onto an unyielding target, and this work is an expansion of those efforts.

  7. A method for relating impacts with yielding and unyielding targets

    SciTech Connect (OSTI)

    Ammerman, D.J.

    1991-12-31T23:59:59.000Z

    The public has questioned the severity of the regulatory 9 meter drop onto an unyielding target required for Type B radioactive material shipping packages since this drop height results in an impact velocity of only 13.3 m/s (30 MPH). It is the unyielding nature of the regulatory target which makes the 9 meter drop so severe. In this paper a method for relating higher velocity impacts with yielding targets to impacts onto an unyielding target is developed. The severity of impacts with yielding targets is decreased by the amount of the impact energy absorbed in damaging the target. There have been previous attempts to correlate impacts with yielding targets to lower velocity impacts onto an unyielding target, and this work is an expansion of those efforts.

  8. Airborne Infrared Target Tracking with the Nintendo Wii Remote Sensor

    E-Print Network [OSTI]

    Beckett, Andrew 1984-

    2012-11-12T23:59:59.000Z

    entirely. This research presents a solution to the target tracking problem which reliably provides automatic target detection and tracking with low expense and computational overhead by making use of the infrared sensor from a Nintendo Wii Remote Controller....

  9. Topo II: An Enzyme Target for Antibacterial and Cancer Drugs

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Topo II: An Enzyme Target for Antibacterial and Cancer Drugs Topo II: An Enzyme Target for Antibacterial and Cancer Drugs Print Wednesday, 27 February 2008 00:00 The veil has...

  10. amphoter target nuclei: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    2001-12-31 3 Absorbed dose in target cell nuclei and dose conversion coefficient of radon progeny Biology and Medicine Websites Summary: Absorbed dose in target cell nuclei and...

  11. Nonresonant and Resonant Frequency-Selectable Induction-Heating Targets

    E-Print Network [OSTI]

    Rodriguez, John I.

    This paper examines a scheme for developing frequency-selectable induction-heating targets for stimulating temperature-sensitive polymer gels. The phrase frequency selectable implies that each target has a frequency at ...

  12. Target GmbH | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov YouKizildere IRaghuraji Agro Industries PvtStratosolar Jump to:Holdings Co08.0Information ExpansionTarget GmbH Jump to:

  13. Target molecules detection by waveguiding in a photonic silicon membrane

    DOE Patents [OSTI]

    Letant, Sonia; Van Buuren, Anthony; Terminello, Louis

    2004-08-31T23:59:59.000Z

    Disclosed herein is a photonic silicon filter capable of binding and detecting biological and chemical target molecules in liquid or gas samples. A photonic waveguiding silicon filter with chemical and/or biological anchors covalently attached to the pore walls selectively bind target molecules. The system uses transmission curve engineering principles to allow measurements to be made in situ and in real time to detect the presence of various target molecules and determine the concentration of bound target.

  14. Target molecules detection by waveguiding in a photonic silicon membrane

    DOE Patents [OSTI]

    Letant, Sonia E. (Livermore, CA); Van Buuren, Anthony (Livermore, CA); Terminello, Louis (Danville, CA); Hart, Bradley R. (Brentwood, CA)

    2006-12-26T23:59:59.000Z

    Disclosed herein is a porous silicon filter capable of binding and detecting biological and chemical target molecules in liquid or gas samples. A photonic waveguiding silicon filter with chemical and/or biological anchors covalently attached to the pore walls bind target molecules. The system uses transmission curve engineering principles to allow measurements to be made in situ and in real time to detect the presence of various target molecules and calculate the concentration of bound target.

  15. Optimization Studies for ISOL Type High-Powered Targets

    SciTech Connect (OSTI)

    Remec, Igor [Oak Ridge National Laboratory] [Oak Ridge National Laboratory; Ronningen, Reginald Martin [Michigan State University] [Michigan State University

    2013-09-24T23:59:59.000Z

    The research studied one-step and two-step Isotope Separation on Line (ISOL) targets for future radioactive beam facilities with high driver-beam power through advanced computer simulations. As a target material uranium carbide in the form of foils was used because of increasing demand for actinide targets in rare-isotope beam facilities and because such material was under development in ISAC at TRIUMF when this project started. Simulations of effusion were performed for one-step and two step targets and the effects of target dimensions and foil matrix were studied. Diffusion simulations were limited by availability of diffusion parameters for UCx material at reduced density; however, the viability of the combined diffusion?effusion simulation methodology was demonstrated and could be used to extract physical parameters such as diffusion coefficients and effusion delay times from experimental isotope release curves. Dissipation of the heat from the isotope-producing targets is the limiting factor for high-power beam operation both for the direct and two-step targets. Detailed target models were used to simulate proton beam interactions with the targets to obtain the fission rates and power deposition distributions, which were then applied in the heat transfer calculations to study the performance of the targets. Results indicate that a direct target, with specification matching ISAC TRIUMF target, could operate in 500-MeV proton beam at beam powers up to ~40 kW, producing ~8 1013 fission/s with maximum temperature in UCx below 2200 C. Targets with larger radius allow higher beam powers and fission rates. For the target radius in the range 9-mm to 30-mm the achievable fission rate increases almost linearly with target radius, however, the effusion delay time also increases linearly with target radius.

  16. A high power beam-on-target test of liquid lithium target for RIA.

    SciTech Connect (OSTI)

    Nolen, J.; Reed, C.; Novick, V.; Specht, J.; Plotkin, P.; Momozaki,Y.; Gomes, I.

    2005-08-29T23:59:59.000Z

    Experiments were conducted to demonstrate the stable operation of a windowless liquid lithium target under extreme thermal loads that are equivalent to uranium beams from the proposed Rare Isotope Accelerator (RIA) driver linac. The engineering and safety issues accompanying liquid lithium systems are first discussed. The liquid metal technology knowledge base generated primarily for fast reactors, and liquid metal cooled fusion reactors, was applied to the development of these systems in a nuclear physics laboratory setting. The use of a high energy electron beam for simulating a high power uranium beam produced by the RIA driver linac is also described. Calculations were performed to obtain energy deposition profiles produced by electron beams at up to a few MeV to compare with expected uranium beam energy deposition profiles. It was concluded that an experimental simulation using a 1-MeV electron beam would be a valuable tool to assess beam-jet interaction. In the experiments, the cross section of the windowless liquid lithium target was 5 mm x 10 mm, which is a 1/3rd scale prototype target, and the velocity of the liquid lithium was varied up to 6 m/s. Thermal loads up to 20 kW within a beam spot diameter of 1mm were applied on the windowless liquid lithium target by the 1-MeV electron beam. The calculations showed that the maximum power density and total power deposited within the target, from the electron beam, was equivalent to that of a 200-kW, 400-MeV/u uranium beam. It was demonstrated that the windowless liquid lithium target flowing at velocities as low as 1.8 m/s stably operated under beam powers up to 20 kW without disruption or excessive vaporization.

  17. Method of making segmented pyrolytic graphite sputtering targets

    DOE Patents [OSTI]

    McKernan, M.A.; Alford, C.S.; Makowiecki, D.M.; Chen, C.W.

    1994-02-08T23:59:59.000Z

    Anisotropic pyrolytic graphite wafers are oriented and bonded together such that the graphite's high thermal conductivity planes are maximized along the back surface of the segmented pyrolytic graphite target to allow for optimum heat conduction away from the sputter target's sputtering surface and to allow for maximum energy transmission from the target's sputtering surface. 2 figures.

  18. Methods for targetted mutagenesis in gram-positive bacteria

    DOE Patents [OSTI]

    Yang, Yunfeng

    2014-05-27T23:59:59.000Z

    The present invention provides a method of targeted mutagenesis in Gram-positive bacteria. In particular, the present invention provides a method that effectively integrates a suicide integrative vector into a target gene in the chromosome of a Gram-positive bacterium, resulting in inactivation of the target gene.

  19. Lead-Bismuth Spallation Target Design Yousry Gohar

    E-Print Network [OSTI]

    McDonald, Kirk

    Lead-Bismuth Spallation Target Design Yousry Gohar Nuclear Engineering Division Argonne National Driven System #12;Lead-Bismuth Spallation Target Design A study was carried out to analyze and design a Lead-Bismuth spallation target for driving a subcritical assembly. Performance Parameters: Produce

  20. Glucose conjugation for the specific targeting and treatment of cancer

    E-Print Network [OSTI]

    Hergenrother, Paul J.

    Glucose conjugation for the specific targeting and treatment of cancer Emilia C. Calvaresia and Paul J. Hergenrother*ab Cancers of diverse origins exhibit marked glucose avidity and high rates has led to an interest in targeting it for cancer therapy. One promising strategy for such targeting

  1. Neutron producing target for accelerator based neutron source for

    E-Print Network [OSTI]

    Taskaev, Sergey Yur'evich

    therapy [1, 2]. Lithium targets for two modes of neutron beam production are developed. The first one. Target will be created as a 2 3 m thick lithium layer on the surface of tungsten disk cooled by liquidW cm2 . ii) Production of target with lithium layer thickness of 2 3 m. #12;248 iii) Evaporation

  2. Electron Scattering with Polarized Targets at TESLA

    E-Print Network [OSTI]

    The TESLA-N Study Group; :; M. Anselmino; E. C. Aschenauer; S. Belostotski; W. Bialowons; J. Bluemlein; V. Braun; R. Brinkmann; M. Dueren; F. Ellinghaus; K. Goeke; St. Goertz; A. Gute; J. Harmsen; D. v. Harrach; R. Jakob; E. M. Kabuss; R. Kaiser; V. Korotkov; P. Kroll; E. Leader; B. Lehmann-Dronke; L. Mankiewicz; A. Meier; W. Meyer; N. Meyners; D. Mueller; P. J. Mulders; W. -D. Nowak; L. Niedermeier; K. Oganessyan; P. V. Pobilitsa; M. V. Polyakov; G. Reicherz; K. Rith; D. Ryckbosch; A. Schaefer; K. Sinram; G. v. d. Steenhoven; E. Steffens; J. Steijger; C. Weiss

    2000-11-24T23:59:59.000Z

    Measurements of polarized electron-nucleon scattering can be realized at the TESLA linear collider facility with projected luminosities that are about two orders of magnitude higher than those expected of other experiments at comparable energies. Longitudinally polarized electrons, accelerated as a small fraction of the total current in the e+ arm of TESLA, can be directed onto a solid state target that may be either longitudinally or transversely polarized. A large variety of polarized parton distribution and fragmentation functions can be determined with unprecedented accuracy, many of them for the first time. A main goal of the experiment is the precise measurement of the x- and Q^2-dependence of the experimentally totally unknown quark transversity distributions that will complete the information on the nucleon's quark spin structure as relevant for high energy processes. Comparing their Q^2-evolution to that of the corresponding helicity distributions constitutes an important precision test of the predictive power of QCD in the spin sector. Measuring transversity distributions and tensor charges allows access to the hitherto unmeasured chirally odd operators in QCD which are of great importance to understand the role of chiral symmetry. The possibilities of using unpolarized targets and of experiments with a real photon beam turn TESLA-N into a versatile next-generation facility at the intersection of particle and nuclear physics.

  3. Recovery of germanium-68 from irradiated targets

    DOE Patents [OSTI]

    Phillips, Dennis R. (Los Alamos, NM); Jamriska, Sr., David J. (Los Alamos, NM); Hamilton, Virginia T. (Los Alamos, NM)

    1993-01-01T23:59:59.000Z

    A process for selective separation of germanium-68 from proton irradiated molybdenum targets is provided and includes dissolving the molybdenum target in a hydrogen peroxide solution to form a first ion-containing solution, contacting the first ion-containing solution with a cationic resin whereby ions selected from the group consisting of molybdenum, niobium, technetium, selenium, vanadium, arsenic, germanium, zirconium and rubidium remain in a second ion-containing solution while ions selected from the group consisting of rubidium, zinc, beryllium, cobalt, iron, manganese, chromium, strontium, yttrium and zirconium are selectively adsorbed by the first resin, adjusting the pH of the second ion-containing solution to within a range of from about 0.7 to about 3.0, adjusting the soluble metal halide concentration in the second ion-containing solution to a level adapted for subsequent separation of germanium, contacting the pH-adjusted, soluble metal halide-containing second ion-containing solution with a dextran-based material whereby germanium ions are separated by the dextran-based material, and recovering the germanium from the dextran-based material, preferably by distillation.

  4. Realizing Technologies for Magnetized Target Fusion

    SciTech Connect (OSTI)

    Wurden, Glen A. [Los Alamos National Laboratory

    2012-08-24T23:59:59.000Z

    Researchers are making progress with a range of magneto-inertial fusion (MIF) concepts. All of these approaches use the addition of a magnetic field to a target plasma, and then compress the plasma to fusion conditions. The beauty of MIF is that driver power requirements are reduced, compared to classical inertial fusion approaches, and simultaneously the compression timescales can be longer, and required implosion velocities are slower. The presence of a sufficiently large Bfield expands the accessibility to ignition, even at lower values of the density-radius product, and can confine fusion alphas. A key constraint is that the lifetime of the MIF target plasma has to be matched to the timescale of the driver technology (whether liners, heavy ions, or lasers). To achieve sufficient burn-up fraction, scaling suggests that larger yields are more effective. To handle the larger yields (GJ level), thick liquid wall chambers are certainly desired (no plasma/neutron damage materials problem) and probably required. With larger yields, slower repetition rates ({approx}0.1-1 Hz) for this intrinsically pulsed approach to fusion are possible, which means that chamber clearing between pulses can be accomplished on timescales that are compatible with simple clearing techniques (flowing liquid droplet curtains). However, demonstration of the required reliable delivery of hundreds of MJ of energy, for millions of pulses per year, is an ongoing pulsed power technical challenge.

  5. Die-target for dynamic powder consolidation

    DOE Patents [OSTI]

    Flinn, J.E.; Korth, G.E.

    1985-06-27T23:59:59.000Z

    A die/target is disclosed for consolidation of a powder, especially an atomized rapidly solidified metal powder, to produce monoliths by the dynamic action of a shock wave, especially a shock wave produced by the detonation of an explosive charge. The die/target comprises a rectangular metal block having a square primary surface with four rectangular mold cavities formed therein to receive the powder. The cavities are located away from the geometrical center of the primary surface and are distributed around such center while also being located away from the geometrical diagonals of the primary surface to reduce the action of reflected waves so as to avoid tensile cracking of the monoliths. The primary surface is covered by a powder retention plate which is engaged by a flyer plate to transmit the shock wave to the primary surface and the powder. Spawl plates are adhesively mounted on other surfaces of the block to act as momentum traps so as to reduce reflected waves in the block. 4 figs.

  6. Complete fabrication of target experimental chamber and implement initial target diagnostics to be used for the first target experiments in NDCX-1

    E-Print Network [OSTI]

    Bieniosek, F.M.

    2008-01-01T23:59:59.000Z

    Drift Compression Magnet Chamber Ion Beam Background Plasmaand reheating of the ion source, the target chamber can betarget chamber ports are reserved for ion beam diagnostics

  7. Complete fabrication of target experimental chamber and implement initial target diagnostics to be used for the first target experiments in NDCX-1

    E-Print Network [OSTI]

    Bieniosek, F.M.

    2008-01-01T23:59:59.000Z

    goal we are envisioning a robot arm, which grabs a preloadedon the end of that robot arm. Our current target manipulator

  8. DEVELOPMENT AND ON-LINE TESTS OF DIFFERENT TARGET-ION SOURCE UNITS FOR PRODUCTION OF NUCLIDES FAR FROM STABILITY

    E-Print Network [OSTI]

    Titov, Anatoly

    as a general goal the development of a massive (up to 1 kg) uranium carbide target prototype for the third beams. For more than thirty years UCx targets have been explored for the production of a large set of neutron-rich and neutron-deficient heavy nuclei. The main line of uranium carbide target development

  9. STUDY OF GRAPHITE TARGETS INTERACTING WITH THE 24 GeV PROTON BEAM OF THE BNL MUON TARGET EXPERIMENT*

    E-Print Network [OSTI]

    McDonald, Kirk

    experiment, graphite and carbon-carbon composite targets were exposed to the AGS beam and their response materials for the future muon collider/neutrino factory carbon-based solid targets have been considered for the experiment are ATJ graphite and the anisotropic carbon-carbon composite. Each target consists of a pair of 16

  10. Targets for on-board hydrogen storage systems: Current R&D focus is on 2010 Targets

    E-Print Network [OSTI]

    storage system) 98% (dry basis) Useful constants: 0.2778kWh/MJ, ~33.3kWh/gal gasoline equivalent. #12Targets for on-board hydrogen storage systems: Current R&D focus is on 2010 Targets Table 1. DOE Technical Targets: On-Board Hydrogen Storage Systemsa, b, c Storage Parameter Units 2007* 2010 2015 Usable

  11. Measurement of Particle Production from the MICE Target

    SciTech Connect (OSTI)

    Soler, F. J. P.; Walaron, K. [Department of Physics and Astronomy, University of Glasgow, Glasgow (United Kingdom); Booth, C.; Carson, M.; Hodgson, P.; Howlett, L.; Smith, P. [Department of Physics and Astronomy, University of Sheffield, Sheffield (United Kingdom); Adams, D.; Edgecock, R.; Murray, W.; Tilley, K. [Rutherford Appleton Laboratory, Science and Technology Facilities Council (United Kingdom); Cobb, J.; Rayner, M. [Sub-department of Nuclear and Particle Physics, University of Oxford, Oxford (United Kingdom); Roberts, T. [Illinois Institute of Technology and Muons Inc., Illinois (United States)

    2008-02-21T23:59:59.000Z

    This article describes the prototype target and the requirements for the target mechanism needed to provide a beam of muons to the Muon Ionization Cooling Experiment (MICE) from the ISIS accelerator at RAL. The mechanism has achieved the required 85g acceleration to be able to insert the target into the ISIS beam during the last 2 ms of the accelerating period. A prototype target test was used to integrate the target into ISIS and to measure the ISIS beam envelope, particle yields and beam loss, showing good agreement between data and simulations.

  12. Multiple source/multiple target fluid transfer apparatus

    DOE Patents [OSTI]

    Turner, Terry D. (Idaho Falls, ID)

    1997-01-01T23:59:59.000Z

    A fluid transfer apparatus includes: a) a plurality of orifices for connection with fluid sources; b) a plurality of orifices for connection with fluid targets; c) a set of fluid source conduits and fluid target conduits associated with the orifices; d) a pump fluidically interposed between the source and target conduits to transfer fluid therebetween; e) a purge gas conduit in fluid communication with the fluid source conduits, fluid target conduits and pump to receive and pass a purge gas under pressure; f) a solvent conduit in fluid communication with the fluid source conduits, fluid target conduits and pump to receive and pass solvent, the solvent conduit including a solvent valve; g) pump control means for controlling operation of the pump; h) purge gas valve control means for controlling operation of the purge gas valve to selectively impart flow of purge gas to the fluid source conduits, fluid target conduits and pump; i) solvent valve control means for controlling operation of the solvent valve to selectively impart flow of solvent to the fluid source conduits, fluid target conduits and pump; and j) source and target valve control means for controlling operation of the fluid source conduit valves and the fluid target conduit valves to selectively impart passage of fluid between a selected one of the fluid source conduits and a selected one of the fluid target conduits through the pump and to enable passage of solvent or purge gas through selected fluid source conduits and selected fluid target conduits.

  13. Tracking target objects orbiting earth using satellite-based telescopes

    DOE Patents [OSTI]

    De Vries, Willem H; Olivier, Scot S; Pertica, Alexander J

    2014-10-14T23:59:59.000Z

    A system for tracking objects that are in earth orbit via a constellation or network of satellites having imaging devices is provided. An object tracking system includes a ground controller and, for each satellite in the constellation, an onboard controller. The ground controller receives ephemeris information for a target object and directs that ephemeris information be transmitted to the satellites. Each onboard controller receives ephemeris information for a target object, collects images of the target object based on the expected location of the target object at an expected time, identifies actual locations of the target object from the collected images, and identifies a next expected location at a next expected time based on the identified actual locations of the target object. The onboard controller processes the collected image to identify the actual location of the target object and transmits the actual location information to the ground controller.

  14. Cryogenic target formation using cold gas jets

    DOE Patents [OSTI]

    Hendricks, Charles D. [Livermore, CA

    1980-02-26T23:59:59.000Z

    A method and apparatus using cold gas jets for producing a substantially uniform layer of cryogenic materials on the inner surface of hollow spherical members having one or more layers, such as inertially imploded targets. By vaporizing and quickly refreezing cryogenic materials contained within a hollow spherical member, a uniform layer of the materials is formed on an inner surface of the spherical member. Basically the method involves directing cold gas jets onto a spherical member having one or more layers or shells and containing the cryogenic material, such as a deuterium-tritium (DT) mixture, to freeze the contained material, momentarily heating the spherical member so as to vaporize the contained material, and quickly refreezing the thus vaporized material forming a uniform layer of cryogenic material on an inner surface of the spherical member.

  15. Laser-fusion targets for reactors

    DOE Patents [OSTI]

    Nuckolls, John H. (Livermore, CA); Thiessen, Albert R. (Livermore, CA)

    1987-01-01T23:59:59.000Z

    A laser target comprising a thermonuclear fuel capsule composed of a centrally located quantity of fuel surrounded by at least one or more layers or shells of material for forming an atmosphere around the capsule by a low energy laser prepulse. The fuel may be formed as a solid core or hollow shell, and, under certain applications, a pusher-layer or shell is located intermediate the fuel and the atmosphere forming material. The fuel is ignited by symmetrical implosion via energy produced by a laser, or other energy sources such as an electron beam machine or ion beam machine, whereby thermonuclear burn of the fuel capsule creates energy for applications such as generation of electricity via a laser fusion reactor.

  16. Cryogenic target formation using cold gas jets

    DOE Patents [OSTI]

    Hendricks, C.D.

    1980-02-26T23:59:59.000Z

    A method and apparatus using cold gas jets for producing a substantially uniform layer of cryogenic materials on the inner surface of hollow spherical members having one or more layers, such as inertially imploded targets are disclosed. By vaporizing and quickly refreezing cryogenic materials contained within a hollow spherical member, a uniform layer of the materials is formed on an inner surface of the spherical member. Basically the method involves directing cold gas jets onto a spherical member having one or more layers or shells and containing the cryogenic material, such as a deuterium-tritium (DT) mixture, to freeze the contained material, momentarily heating the spherical member so as to vaporize the contained material, and quickly refreezing the thus vaporized material forming a uniform layer of cryogenic material on an inner surface of the spherical member. 4 figs.

  17. Tenth target fabrication specialists` meeting: Proceedings

    SciTech Connect (OSTI)

    Foreman, L.R.; Stark, J.C. [comp.

    1995-11-01T23:59:59.000Z

    This tenth meeting of specialists in target fabrication for inertial confinement is unique in that it is the first meeting that was completely unclassified. As a result of the new classification, we were able to invite more foreign participation. In addition to participants from the US, UK, and Canada, representatives from France, Japan, and two Russian laboratories attended, about 115 in all. This booklet presents full papers and poster sessions. Indirect and direct drive laser implosions are considered. Typical topics include: polymer or aluminium or resorcinol/formaldehyde shells, laser technology, photon tunneling microscopy as a characterization tool, foams, coatings, hohlraums, and beryllium capsules. Hydrogen, deuterium, tritium, and beryllium are all considered as fuels.

  18. Novel Insights into the Downstream Pathways and Targets Controlled by Transcription Factors CREM in the Testis

    E-Print Network [OSTI]

    2012-01-01T23:59:59.000Z

    proteins in spermatids: Downstream targets and implicationsNovel Insights into the Downstream Pathways and TargetsNovel Insights into the Downstream Pathways and Targets

  19. Construction of an unyielding target for large horizontal impacts.

    SciTech Connect (OSTI)

    Ammerman, Douglas James; Davie, Neil Thomas; Kalan, Robert J.

    2010-10-01T23:59:59.000Z

    Sandia National Laboratories has constructed an unyielding target at the end of its 2000-foot rocket sled track. This target is made up of approximately 5 million pounds of concrete, an embedded steel load spreading structure, and a steel armor plate face that varies from 10 inches thick at the center to 4 inches thick at the left and right edges. The target/track combination will allow horizontal impacts at regulatory speeds of very large objects, such as a full-scale rail cask, or high-speed impacts of smaller packages. The load-spreading mechanism in the target is based upon the proven design that has been in use for over 20 years at Sandia's aerial cable facility. That target, with a weight of 2 million pounds, has successfully withstood impact forces of up to 25 million pounds. It is expected that the new target will be capable of withstanding impact forces of more than 70 million pounds. During construction various instrumentation was placed in the target so that the response of the target during severe impacts can be monitored. This paper will discuss the construction of the target and provide insights on the testing capabilities at the sled track with this new target.

  20. Proceedings of the workshop on polarized targets in storage rings

    SciTech Connect (OSTI)

    Holt, R.J. (ed.)

    1984-08-01T23:59:59.000Z

    Polarization phenomena have played an increasingly important part in the study of nuclei and nucleons in recent years. Polarization studies have been hampered by the relatively few and rather fragile polarized targets which are presently available. The concept of polarized gas targets in storage rings opens a much wider range of possibilities than is available in the external target geometry. This novel method will represent a considerable advance in nuclear physics and will continue to receive much attention in plans for future facilities. An internal, polarized-target station is being planned for the cooler ring at the Indiana University Cyclotron Facility. Internal targets are compatible with recent designs of electron accelerators proposed by the Massachusetts Institute of Technology and the Southeastern Universities Research Association. The key to nuclear-science programs based on internal targets pivots on recent developments in polarized atomic beam methods, which include the more recent laser-driven polarized targets. The workshop drew together a unique group of physicists in the fields of high-energy, nuclear and atomic physics. The meeting was organized in a manner that stimulated discussion among the 58 participants and focused on developments in polarized target technology and the underlying atomic physics. An impressive array of future possibilities for polarized targets as well as current developments in polarized target technology were discussed at the workshop. Abstracts of individual items from the workshop were prepared separately for the data base.

  1. LANL: AOT & LANSCE The PULSE July 2010

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ing siMuLations 4 heads up feature: Lansce and aot division MeMbers recognized with poLLution prevention awards Mark III spallation neutron target completed On June 9, shortly...

  2. An effective loading method of americium targets in fast reactors

    SciTech Connect (OSTI)

    Ohki, Shigeo; Sato, Isamu; Mizuno, Tomoyasu; Hayashi, Hideyuki; Tanaka, Kenya [Japan Atomic Energy Agency, 4002, Narita-cho, O-arai-machi, Higashi-Ibaraki-gun, Ibaraki 311-1393 (Japan)

    2007-07-01T23:59:59.000Z

    Recently, the development of target fuel with high americium (Am) content has been launched for the reduction of the overall fuel fabrication cost of the minor actinide (MA) recycling. In the framework of the development, this study proposes an effective loading method of Am targets in fast reactors. As a result of parametric survey calculations, we have found the ring-shaped target loading pattern between inner and outer core regions. This loading method is satisfactory both in core characteristics and in MA transmutation property. It should be noted that the Am targets can contribute to the suppression of the core power distribution change due to burnup. The major drawback of Am target is the production of helium gas. A target design modification by increasing the cladding thickness is found to be the most feasible measure to cope with the helium production. (authors)

  3. Method of detecting luminescent target ions with modified magnetic microspheres

    DOE Patents [OSTI]

    Shkrob, Ilya A; Kaminski, Michael D

    2014-05-13T23:59:59.000Z

    This invention provides methods of using modified magnetic microspheres to extract target ions from a sample in order to detect their presence in a microfluidic environment. In one or more embodiments, the microspheres are modified with molecules on the surface that allow the target ions in the sample to form complexes with specific ligand molecules on the microsphere surface. In one or more embodiments, the microspheres are modified with molecules that sequester the target ions from the sample, but specific ligand molecules in solution subsequently re-extract the target ions from the microspheres into the solution, where the complexes form independent of the microsphere surface. Once the complexes form, they are exposed to an excitation wavelength light source suitable for exciting the target ion to emit a luminescent signal pattern. Detection of the luminescent signal pattern allows for determination of the presence of the target ions in the sample.

  4. Inertial fusion energy target injection, tracking, and beam pointing

    SciTech Connect (OSTI)

    Petzoldt, R.W.

    1995-03-07T23:59:59.000Z

    Several cryogenic targets must be injected each second into a reaction chamber. Required target speed is about 100 m/s. Required accuracy of the driver beams on target is a few hundred micrometers. Fuel strength is calculated to allow acceleration in excess of 10,000 m/s{sup 2} if the fuel temperature is less than 17 K. A 0.1 {mu}m thick dual membrane will allow nearly 2,000 m/s{sup 2} acceleration. Acceleration is gradually increased and decreased over a few membrane oscillation periods (a few ms), to avoid added stress from vibrations which could otherwise cause a factor of two decrease in allowed acceleration. Movable shielding allows multiple targets to be in flight toward the reaction chamber at once while minimizing neutron heating of subsequent targets. The use of multiple injectors is recommended for redundancy which increases availability and allows a higher pulse rate. Gas gun, rail gun, induction accelerator, and electrostatic accelerator target injection devices are studied, and compared. A gas gun is the preferred device for indirect-drive targets due to its simplicity and proven reliability. With the gas gun, the amount of gas required for each target (about 10 to 100 mg) is acceptable. A revolver loading mechanism is recommended with a cam operated poppet valve to control the gas flow. Cutting vents near the muzzle of the gas gun barrel is recommended to improve accuracy and aid gas pumping. If a railgun is used, we recommend an externally applied magnetic field to reduce required current by an order of magnitude. Optical target tracking is recommended. Up/down counters are suggested to predict target arrival time. Target steering is shown to be feasible and would avoid the need to actively point the beams. Calculations show that induced tumble from electrostatically steering the target is not excessive.

  5. Cosmogenic activation of a natural tellurium target

    E-Print Network [OSTI]

    Lozza, V

    2014-01-01T23:59:59.000Z

    130Te is one of the candidates for the search for neutrinoless double beta decay. It is currently planned to be used in two experiments: CUORE and SNO+. In the CUORE experiment TeO2 crystals cooled at cryogenic temperatures will be used. In the SNO+ experiment natTe will be deployed up to 0.3% loading in the liquid scintillator volume. A possible background for the signal searched for, are the high Q-value, long-lived isotopes, produced by cosmogenic neutron and proton spallation reaction on the target material. A total of 18 isotopes with Q-value larger than 2 MeV and T1/2 >20 days have been identified as potential backgrounds. In addition low Q-value, high rate isotopes can be problematic due to pile-up effects, specially in liquid scintillator based detectors. Production rates have been calculated using the ACTIVIA program, the TENDL library, and the cosmogenic neutron and proton flux parametrization at sea level from Armstrong and Gehrels for both long and short lived isotopes. The obtained values for the...

  6. Automatic target recognition apparatus and method

    DOE Patents [OSTI]

    Baumgart, Chris W. (Santa Fe, NM); Ciarcia, Christopher A. (Los Alamos, NM)

    2000-01-01T23:59:59.000Z

    An automatic target recognition apparatus (10) is provided, having a video camera/digitizer (12) for producing a digitized image signal (20) representing an image containing therein objects which objects are to be recognized if they meet predefined criteria. The digitized image signal (20) is processed within a video analysis subroutine (22) residing in a computer (14) in a plurality of parallel analysis chains such that the objects are presumed to be lighter in shading than the background in the image in three of the chains and further such that the objects are presumed to be darker than the background in the other three chains. In two of the chains the objects are defined by surface texture analysis using texture filter operations. In another two of the chains the objects are defined by background subtraction operations. In yet another two of the chains the objects are defined by edge enhancement processes. In each of the analysis chains a calculation operation independently determines an error factor relating to the probability that the objects are of the type which should be recognized, and a probability calculation operation combines the results of the analysis chains.

  7. Office of Enterprise Assessments Targeted Review of Work Planning...

    Office of Environmental Management (EM)

    Targeted Review of Work Planning and Control at the Hanford Tank Farms April 2015 Office of Worker Safety and Health Assessments Office of Environment, Safety and Health...

  8. alliance targets separation: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    We find the largest significant increases in targets stock prices, investment, and operating profitability when ownership is combined with alliances, joint ventures, and...

  9. Protein engineering for targeted delivery of radionuclides to tumors

    E-Print Network [OSTI]

    Orcutt, Kelly Davis

    2010-01-01T23:59:59.000Z

    Traditional cancer treatment strategies include systemic chemotherapy, external beam radiation, and surgical excision. Chemotherapy is nonspecific, and targets all rapidly dividing cells. External beam radiation and surgery ...

  10. anticancer therapeutics targeting: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    demonstra Rizzo, Robert C. 3 Helicobacter pylon: Therapeutic Targets CiteSeer Summary: Helicobacter pylori is now considered a major pathogen of the upper gastrointestinal...

  11. attractive therapeutic target: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    stem cells. Jw Shay; Wn Keith 3 Helicobacter pylon: Therapeutic Targets CiteSeer Summary: Helicobacter pylori is now considered a major pathogen of the upper gastrointestinal...

  12. architectures targeting hdtv: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of already sto... Harrick Vin; P. Venkat Rangan 1993-01-01 2 FPGA-TARGETED NEURAL ARCHITECTURE FOR EMBEDDED ALERTNESS DETECTION Computer Technologies and Information Sciences...

  13. acetylcholinesterase target site: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biology and Medicine Websites Summary: Theoretical and Computational Modeling of Target-Site Search Kinetics In Vitro and In Vivo Elena F Engineering Department, Stanford...

  14. NREL 2012 Achievement of Ethanol Cost Targets: Biochemical Ethanol...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NREL 2012 Achievement of Ethanol Cost Targets: Biochemical Ethanol Fermentation via Dilute-Acid Pretreatment and Enzymatic Hydrolysis of Corn Stover Ling Tao, Dan Schell, Ryan...

  15. Mutations and genetic targets for enhanced L-tyrosine production

    DOE Patents [OSTI]

    Santos, Christine; Stephanopoulos, Gregory

    2014-05-27T23:59:59.000Z

    The invention relates to identification of mutations and genetic targets for enhanced L-tyrosine production, and bacterial strains capable of L-tyrosine production.

  16. Marketing Edge Consulting Group and TargetGov Successful Marketing...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Edge Consulting Group and TargetGov Networking Opportunities * Solid Handshake * Solid eye contact * Bring business cards * Wear name tag on RIGHT * Food and drink- have your...

  17. Establishing Thermo-Electric Generator (TEG) Design Targets for...

    Broader source: Energy.gov (indexed) [DOE]

    for Hybrid Vehicles Establishing Thermo-Electric Generator (TEG) Design Targets for Hybrid Vehicles 2013 DOE Hydrogen and Fuel Cells Program and Vehicle Technologies Program...

  18. Establishing Thermo-Electric Generator (TEG) Design Targets for...

    Broader source: Energy.gov (indexed) [DOE]

    Establishing Thermo-Electric Generator (TEG) Design Targets for Hybrid Vehicles 2013 DOE Hydrogen Program and Vehicle Technologies Annual Merit Review May 15th, 2013 R.Vijayagopal,...

  19. Targeted Protein Degradation by Salmonella under Phagosome-Mimicking...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Protein Degradation by Salmonella under Phagosome-Mimicking Culture Conditions Investigated Using Comparative Targeted Protein Degradation by Salmonella under Phagosome-Mimicking...

  20. Miami-Dade County- Targeted Jobs Incentive Fund

    Broader source: Energy.gov [DOE]

    The Targeted Jobs Incentive Fund (TJIF) provides financial incentives for select industries, including solar thermal and photovoltaic manufacturing, installation and repair companies that are...

  1. Targeted Tandem Mass Spectrometry for High-Throughput Comparative...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    states. Herein, we report on a targeted LC-MSMS capability realized with a 7 Tesla Fourier transform ion cyclotron resonance (FTICR) mass spectrometer equipped with a...

  2. Cyclotrons to Make Neutrons & Radioactive Targets for SBSS at...

    Office of Science (SC) Website

    Cyclotrons to Make Neutrons & Radioactive Targets for SBSS at LBNL Nuclear Physics (NP) NP Home About Research Facilities Science Highlights Benefits of NP Applications of Nuclear...

  3. LE TARGET COSTING UN ETAT DE L'ART

    E-Print Network [OSTI]

    Paris-Sud XI, Universit de

    cls . cot cible conception cot objectif concourance analyse de la valeur kaizen costing Keywords. target costing - design to cost concurrent ingineeringg value analysis kaizen costing

  4. Target enumeration via integration over planar sensor networks

    E-Print Network [OSTI]

    Ghrist, Robert W.

    ]. With this promise, however, comes many challenges, including power consumption, heat dissipation, and communication. We consider how to solve a simple data aggregation problem -- counting unidentified targets

  5. antimony 120 target: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    (red); superconducting coil 1 (turquoise magnet (red); SC 1 (turquoise); 15-T superconduct- ing magnet (blue); total field (magenta); & desired McDonald, Kirk 319 Targeting...

  6. automated radiation targeting: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    diffraction radiation (ODR) as a diagnostic tool has increased Sen, Tanaji 9 Radiation damage of the ILC positron source target CERN Preprints Summary: The radiation damage of the...

  7. actinide target preparation: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    around the Coulomb barrier CERN Preprints Summary: In order to describe heavy-ion fusion reactions around the Coulomb barrier with an actinide target nucleus, we propose a...

  8. A novel charged-particle diagnostic for compression in inertial confinement fusion targets

    E-Print Network [OSTI]

    several cru- cial aspects of an igniting target: the degree of self-heating in the target, its fractional

  9. DNA methylation map of mouse and human brain identifies target genes in Alzheimer's disease

    E-Print Network [OSTI]

    2013-01-01T23:59:59.000Z

    al. Figure 3 Epigenetic deregulation of target genes in the3027 Figure 2 Epigenetic deregulation of target genes in

  10. Effect of inactive impurities on the burning of ICF targets

    SciTech Connect (OSTI)

    Gus'kov, S. Yu. [Russian Academy of Sciences, Lebedev Physical Institute (Russian Federation); Il'in, D. V.; Sherman, V. E. [St. Petersburg State Engineering Institute (Russian Federation)

    2011-12-15T23:59:59.000Z

    The efficiency of thermonuclear burning of the spherical deuterium-tritium (DT) plasma of inertial confinement fusion (ICF) targets in the presence of low-Z impurities (such as lithium, carbon, or beryllium) with arbitrary concentrations is investigated. The effect of impurities produced due to the mixing of the thermonuclear fuel with the material of the structural elements of the target during its compression on the process of target burning is studied, and the possibility of using solid noncryogenic thermonuclear fuels in ICF targets is analyzed. Analytical dependences of the ignition energy and target thermonuclear gain on the impurity concentration are obtained. The models are constructed for homogeneous and inhomogeneous plasmas for the case in which the burning is initiated in the central heated region of the target and then propagates into the surrounding relatively cold fuel. Two possible configurations of an inhomogeneous plasma, namely, an isobaric configuration formed in the case of spark ignition of the target and an isochoric configuration formed in the case of fast ignition, are considered. The results of numerical simulations of the burning of the DT plasma of ICF targets in a wide range of impurity concentrations are presented. The simulations were performed using the TEPA one-dimensional code, in which the thermonuclear burning kinetics is calculated by the Monte Carlo method. It is shown that the strongest negative effect related to the presence of impurities is an increase in the energy of target ignition. It is substantiated that the most promising solid noncryogenic fuel is DT hydride of beryllium (BeDT). The requirements to the plasma parameters at which BeDT can be used as a fuel in noncryogenic ICF targets are determined. Variants of using noncryogenic targets with a solid thermonuclear fuel are proposed.

  11. Quantum fields with noncommutative target spaces

    SciTech Connect (OSTI)

    Balachandran, A. P.; Queiroz, A. R.; Marques, A. M.; Teotonio-Sobrinho, P. [Department of Physics, Syracuse University, Syracuse, New York 13244-1130 (United States); Centro Internacional de Fisica da Materia Condensada, Universidade de Brasilia, C.P. 04667, Brasilia, SP (Brazil); Instituto de Fisica, Universidade de Sao Paulo, C.P. 66318, Sao Paulo, SP, 05315-970 (Brazil)

    2008-05-15T23:59:59.000Z

    Quantum field theories (QFT's) on noncommutative spacetimes are currently under intensive study. Usually such theories have world sheet noncommutativity. In the present work, instead, we study QFT's with commutative world sheet and noncommutative target space. Such noncommutativity can be interpreted in terms of twisted statistics and is related to earlier work of Oeckl [R. Oeckl, Commun. Math. Phys. 217, 451 (2001).], and others [A. P. Balachandran, G. Mangano, A. Pinzul, and S. Vaidya, Int. J. Mod. Phys. A 21, 3111 (2006); A. P. Balachandran, A. Pinzul, and B. A. Qureshi, Phys. Lett. B 634, 434 (2006); A. P. Balachandran, A. Pinzul, B. A. Qureshi, and S. Vaidya, arXiv:hep-th/0608138; A. P. Balachandran, T. R. Govindarajan, G. Mangano, A. Pinzul, B. A. Qureshi, and S. Vaidya, Phys. Rev. D 75, 045009 (2007); A. Pinzul, Int. J. Mod. Phys. A 20, 6268 (2005); G. Fiore and J. Wess, Phys. Rev. D 75, 105022 (2007); Y. Sasai and N. Sasakura, Prog. Theor. Phys. 118, 785 (2007)]. The twisted spectra of their free Hamiltonians has been found earlier by Carmona et al. [J. M. Carmona, J. L. Cortes, J. Gamboa, and F. Mendez, Phys. Lett. B 565, 222 (2003); J. M. Carmona, J. L. Cortes, J. Gamboa, and F. Mendez, J. High Energy Phys. 03 (2003) 058]. We review their derivation and then compute the partition function of one such typical theory. It leads to a deformed blackbody spectrum, which is analyzed in detail. The difference between the usual and the deformed blackbody spectrum appears in the region of high frequencies. Therefore we expect that the deformed blackbody radiation may potentially be used to compute a Greisen-Zatsepin-Kuzmin cutoff which will depend on the noncommutative parameter {theta}.

  12. Harms of Unintentional Leaks during Volume Targeted Pressure Support Ventilation

    E-Print Network [OSTI]

    Paris-Sud XI, Universit de

    1 Harms of Unintentional Leaks during Volume Targeted Pressure Support Ventilation Sonia Khirani1 Background: Volume targeted pressure support ventilation (VT-PSV) is a hybrid mode increasingly used. The objective of the study was to determine the ability of home ventilators to maintain the preset minimal VT

  13. Vacuum aperture isolator for retroreflection from laser-irradiated target

    DOE Patents [OSTI]

    Benjamin, Robert F. (Los Alamos, NM); Mitchell, Kenneth B. (Los Alamos, NM)

    1980-01-01T23:59:59.000Z

    The disclosure is directed to a vacuum aperture isolator for retroreflection of a laser-irradiated target. Within a vacuum chamber are disposed a beam focusing element, a disc having an aperture and a recollimating element. The edge of the focused beam impinges on the edge of the aperture to produce a plasma which refracts any retroreflected light from the laser's target.

  14. ARRA Proposed Award: Downtown Oakland Targeted Measure Saturation Program

    E-Print Network [OSTI]

    : Community Energy Services Corporation City of Oakland Circlepoint Multimedia Design Estimated Full buildings in a dense, 120 block area in the City of Oakland that is an economically disadvantaged areaARRA Proposed Award: Downtown Oakland Targeted Measure Saturation Program Targeting the City

  15. A Constant Gain Kalman Filter Approach to track Maneuvering Targets

    E-Print Network [OSTI]

    Naik, Naren

    1 A Constant Gain Kalman Filter Approach to track Maneuvering Targets Ashwin Yadav1 , Peeyush domains. One of the most fundamental and widely used approaches to target tracking is the Kalman filter. In presence of unknown noise statistics there are difficulties in the Kalman filter yielding acceptable

  16. SUBBAND KALMAN FILTERING WITH APPLICATIONS TO TARGET TRACKING

    E-Print Network [OSTI]

    De Leon, Phillip

    SUBBAND KALMAN FILTERING WITH APPLICATIONS TO TARGET TRACKING P. De Leon1 , W. Kober2 , K, USA ABSTRACT The Kalman filter has been successfully applied to target tracking. However, the Kalman is large. Furthermore, noisy measurements may decrease Kalman filter tracking accuracy. One way to possibly

  17. Target selection and current status of structural genomics for the

    E-Print Network [OSTI]

    Babu, M. Madan

    33 Target selection and current status of structural genomics for the completed microbial genomes 3.2 Structural status of completed microbial genomes in the PDB................ 3.3 Metabolic pathways as targets for structural genomics.......................... 3.3.1 Glycolytic pathway

  18. MATERIAL STUDIES FOR PULSED HIGH-INTENSITY PROTON BEAM TARGETS

    E-Print Network [OSTI]

    McDonald, Kirk

    /mechanical property changes experiment for baseline materials Carbon-Carbon composite This low-Z composite gives;PHASE I: Graphite & Carbon-Carbon Targets #12;E951 Results: ATJ Graphite vs. Carbon-Carbon CompositePLAN MATERIAL STUDIES FOR PULSED HIGH-INTENSITY PROTON BEAM TARGETS Nicholas Simos, Harold Kirk

  19. Click Dimers To Target HIV TAR RNA Conformation Sunil Kumar,

    E-Print Network [OSTI]

    Stuart, Steven J.

    with high affinity toward TAR show promising anti-HIV activity. Ribonucleic acid-protein interactionsClick Dimers To Target HIV TAR RNA Conformation Sunil Kumar, Patrick Kellish, W. Edward Robinson and length in the linker region to target the human immunode- ficiency virus type 1 (HIV-1) TAR RNA region

  20. Scrap biofuels targets and focus on improved public transport

    E-Print Network [OSTI]

    Scrap biofuels targets and focus on improved public transport Friends of the Earth's biofuels campaigner Kenneth Richter argues that biofuel targets are a distraction from tried-and-tested ways to biofuel crops such as rapeseed have changed as more research has been done into their impact

  1. High flux heat transfer in a target environment

    E-Print Network [OSTI]

    McDonald, Kirk

    High flux heat transfer in a target environment T. Davenne High Power Targets Group Rutherford Valid for: Consider turbulent heat transfer in a 1.5mm diameter pipe Dittus Boelter correlation Achenbach correlation for heat transfer in a packed bed of spheres Max power density for a sphere

  2. Using a Cognitive Architecture for Opponent Target Prediction

    E-Print Network [OSTI]

    Demiris, Yiannis

    Using a Cognitive Architecture for Opponent Target Prediction Simon Butler1 and Yiannis Demiris1 what the opponent is doing and predict their possible future actions. In this paper we show an approach in this paper is to predict which target the opponent is heading towards, in an RTS-style game. We improve

  3. Investigation into Fusion Feasibility of a Magnetized Target Fusion Reactor

    E-Print Network [OSTI]

    Wetton, Brian

    Investigation into Fusion Feasibility of a Magnetized Target Fusion Reactor Michael Lindstrom fusion en- ergy known as a magnetized target fusion reactor, in which an intense pressure wave the fusion reactor design we have chosen to model. In section 2, we present a simplified model and set

  4. International Nuclear Target Development Society workshop 1983: proceedings

    SciTech Connect (OSTI)

    Thomas, G. (ed.)

    1983-01-01T23:59:59.000Z

    Separate abstracts were prepared for 11 of the 19 papers presented. Eight papers were previously included in the data base. Discussion group session papers on carbon stripper foils, problems in producing heavy-ion targets, and problems in producing general type targets are included. (WHK)

  5. Models for Offender Target Location Selection with Explicit Dependency Structures

    E-Print Network [OSTI]

    O'Leary, Michael

    Models for Offender Target Location Selection with Explicit Dependency Structures Mike O'Leary April 30 - May 1, 2012 O'Leary & Tucker (Towson University) Target Location Selection QMDNS 2012 1 / 54 in this study We thank Phil Canter from the Baltimore County Police Department for his assistance. O'Leary

  6. Monte Carlo modeling of spallation targets containing uranium and americium

    E-Print Network [OSTI]

    Yury Malyshkin; Igor Pshenichnov; Igor Mishustin; Walter Greiner

    2014-05-02T23:59:59.000Z

    Neutron production and transport in spallation targets made of uranium and americium are studied with a Geant4-based code MCADS (Monte Carlo model for Accelerator Driven Systems). A good agreement of MCADS results with experimental data on neutron- and proton-induced reactions on $^{241}$Am and $^{243}$Am nuclei allows to use this model for simulations with extended Am targets. It was demonstrated that MCADS model can be used for calculating the values of critical mass for $^{233,235}$U, $^{237}$Np, $^{239}$Pu and $^{241}$Am. Several geometry options and material compositions (U, U+Am, Am, Am$_2$O$_3$) are considered for spallation targets to be used in Accelerator Driven Systems. All considered options operate as deep subcritical targets having neutron multiplication factor of $k \\sim 0.5$. It is found that more than 4 kg of Am can be burned in one spallation target during the first year of operation.

  7. Hybrid-drive implosion system for ICF targets

    DOE Patents [OSTI]

    Mark, J.W.K.

    1987-10-14T23:59:59.000Z

    Hybrid-drive implosion systems for ICF targets are described which permit a significant increase in target gain at fixed total driver energy. The ICF target is compressed in two phases, an initial compression phase and a final peak power phase, with each phase driven by a separate, optimized driver. The targets comprise a hollow spherical ablator surroundingly disposed around fusion fuel. The ablator is first compressed to higher density by a laser system, or by an ion beam system, that in each case is optimized for this initial phase of compression of the target. Then, following compression of the ablator, energy is directly delivered into the compressed ablator by an ion beam driver system that is optimized for this second phase of operation of the target. The fusion fuel is driven, at high gain, to conditions wherein fusion reactions occur. This phase separation allows hydrodynamic efficiency and energy deposition uniformity to be individually optimized, thereby securing significant advantages in energy gain. In additional embodiments, the same or separate drivers supply energy for ICF target implosion. 3 figs.

  8. Hybrid-drive implosion system for ICF targets

    DOE Patents [OSTI]

    Mark, James W. (Danville, CA)

    1988-01-01T23:59:59.000Z

    Hybrid-drive implosion systems (20,40) for ICF targets (10,22,42) are described which permit a significant increase in target gain at fixed total driver energy. The ICF target is compressed in two phases, an initial compression phase and a final peak power phase, with each phase driven by a separate, optimized driver. The targets comprise a hollow spherical ablator (12) surroundingly disposed around fusion fuel (14). The ablator is first compressed to higher density by a laser system (24), or by an ion beam system (44), that in each case is optimized for this initial phase of compression of the target. Then, following compression of the ablator, energy is directly delivered into the compressed ablator by an ion beam driver system (30,48) that is optimized for this second phase of operation of the target. The fusion fuel (14) is driven, at high gain, to conditions wherein fusion reactions occur. This phase separation allows hydrodynamic efficiency and energy deposition uniformity to be individually optimized, thereby securing significant advantages in energy gain. In additional embodiments, the same or separate drivers supply energy for ICF target implosion.

  9. Accelerator-based fusion with a low temperature target

    SciTech Connect (OSTI)

    Phillips, R. E.; Ordonez, C. A. [Department of Physics, University of North Texas, Denton, Texas 76203-5017 (United States)

    2013-04-19T23:59:59.000Z

    Neutron generators are in use in a number of scientific and commercial endeavors. They function by triggering fusion reactions between accelerated ions (usually deuterons) and a stationary cold target (e.g., containing tritium). This setup has the potential to generate energy. It has been shown that if the energy transfer between injected ions and target electrons is sufficiently small, net energy gain can be achieved. Three possible avenues are: (a) a hot target with high electron temperature, (b) a cold non-neutral target with an electron deficiency, or (c) a cold target with a high Fermi energy. A study of the third possibility is reported in light of recent research that points to a new phase of hydrogen, which is hypothesized to be related to metallic hydrogen. As such, the target is considered to be composed of nuclei and delocalized electrons. The electrons are treated as conduction electrons, with the average minimum excitation energy being approximately equal to 40% of the Fermi energy. The Fermi energy is directly related to the electron density. Preliminary results indicate that if the claimed electron densities in the new phase of hydrogen were achieved in a target, the energy transfer to electrons would be small enough to allow net energy gain.

  10. Rep-Rated Target Injection for Inertial Fusion Energy

    SciTech Connect (OSTI)

    Frey, D.T.; Goodin, D.T.; Stemke, R.W.; Petzoldt, R.W.; Drake, T.J.; Egli, W.; Vermillion, B.A.; Klasen, R.; Cleary, M.M

    2005-05-15T23:59:59.000Z

    Inertial Fusion Energy (IFE) with laser drivers is a pulsed power generation system that relies on repetitive, high-speed injection of targets into a fusion reactor. To produce an economically viable IFE power plant the targets must be injected into the reactor at a rate between 5 and 10 Hz.To survive the injection process, direct drive (laser fusion) targets (spherical capsules) are placed into protective sabots. The sabots separate from the target and are stripped off before entering the reactor chamber. Indirect drive (heavy ion fusion) utilizes a hohlraum surrounding the spherical capsule and enters the chamber as one piece.In our target injection demonstration system, the sabots or hohlraums are injected into a vacuum system with a light gas gun using helium as a propellant. To achieve pulsed operation a rep-rated injection system has been developed. For a viable power plant we must be able to fire continuously at 6 Hz. This demonstration system is currently set up to allow bursts of up to 12 targets at 6 Hz. Using the current system, tests have been successfully run with direct drive targets to show sabot separation under vacuum and at barrel exit velocities of {approx}400 m/s.The existing revolver system along with operational data will be presented.

  11. A Helium Gas-Scintillator Active Target for Photoreaction Measurements

    E-Print Network [OSTI]

    R. Al Jebali; J. R. M. Annand; J. -O. Adler; I. Akkurt; E. Buchanan; J. Brudvik; K. Fissum; S. Gardner; D. J. Hamilton; K. Hansen; L. Isaksson; K. Livingston; M. Lundin; J. C. McGeorge; I. J. D. MacGregor; R. MacRae; D. G. Middleton; A. J. H. Reiter; G. Rosner; B. Schrder; J. Sjgren; D. Sokhan; B. Strandberg

    2015-03-18T23:59:59.000Z

    A multi-cell He gas-scintillator active target, designed for the measurement of photoreaction cross sections, is described. The target has four main chambers, giving an overall thickness of 0.103 $\\mathrm{g/cm^{2}}$ at an operating pressure of 2 MPa. Scintillations are read out by photomultiplier tubes and the addition of small amounts of $\\mathrm{N}_{2}$ to the He, to shift the scintillation emission from UV to visible, is discussed. First results of measurements at the MAX IV Laboratory tagged-photon facility show that the target has good timing resolution and can cope well with a high-flux photon beam. The determination of reaction cross sections from target yields relies on a Monte Carlo simulation, which considers scintillation light transport, photodisintegration processes in $^{4}\\mathrm{He}$, background photon interactions in target windows and interactions of the reaction-product particles in the gas and target container. The predictions of this simulation are compared to the measured target response.

  12. A Helium Gas-Scintillator Active Target for Photoreaction Measurements

    E-Print Network [OSTI]

    Jebali, R Al; Adler, J -O; Akkurt, I; Buchanan, E; Brudvik, J; Fissum, K; Gardner, S; Hamilton, D J; Hansen, K; Isaksson, L; Livingston, K; Lundin, M; McGeorge, J C; MacGregor, I J D; MacRae, R; Middleton, D G; Reiter, A J H; Rosner, G; Schrder, B; Sjgren, J; Sokhan, D; Strandberg, B

    2015-01-01T23:59:59.000Z

    A multi-cell He gas-scintillator active target, designed for the measurement of photoreaction cross sections, is described. The target has four main chambers, giving an overall thickness of 0.103 $\\mathrm{g/cm^{2}}$ at an operating pressure of 2 MPa. Scintillations are read out by photomultiplier tubes and the addition of small amounts of $\\mathrm{N}_{2}$ to the He, to shift the scintillation emission from UV to visible, is discussed. First results of measurements at the MAX IV Laboratory tagged-photon facility show that the target has good timing resolution and can cope well with a high-flux photon beam. The determination of reaction cross sections from target yields relies on a Monte Carlo simulation, which considers scintillation light transport, photodisintegration processes in $^{4}\\mathrm{He}$, background photon interactions in target windows and interactions of the reaction-product particles in the gas and target container. The predictions of this simulation are compared to the measured target response...

  13. Electron loss from fast heavy ions: Target-scaling dependence

    SciTech Connect (OSTI)

    DuBois, R. D. [Department of Physics, Missouri University of Science and Technology, Rolla, Missouri 65409 (United States); Santos, A. C. F.; Montenegro, E. C. [Instituto de Fisica, UFRJ, Caixa Postal 68528 Rio de Janeiro, BR-21941-972 RJ (Brazil); Sigaud, G. M. [Departamento de Fisica, Pontificia Universidade Catolica do Rio de Janeiro, Caixa Postal 38071, Rio de Janeiro, BR-22452-970 RJ (Brazil)

    2011-08-15T23:59:59.000Z

    The target dependence for projectile electron loss is investigated using experimental data taken from the literature. Impact energies range from a few tens of eV/u to tens of MeV/u. For energies less than several MeV/u, the target dependences are shown to be very similar, independent of projectile species and charge state. Overall, however, with increasing impact energy the cross-section dependence on the target nuclear charge systematically increases. It is shown that none of the existing cross-section target scaling models reproduce these features. A model, based on Born scaling and including both the antiscreening and screening contributions to projectile electron loss, is developed. With the inclusion of relativistic effects, which increase the contribution from both channels at high energies, and ''target saturation'' effects, which reduce the contribution from the screening term for heavy targets and lower impact energies, this model describes quite reasonably all available experimental data. A simple scaling formula that reproduces the measured atomic number and impact velocity dependences is provided. This formula is applicable for projectile electron loss in collisions with either atomic or molecular targets and for impact energies ranging from a few to tens of MeV/u.

  14. Structural mapping of the ClpB ATPases of Plasmodium falciparum: Targeting protein folding and secretion for antimalarial drug design.

    E-Print Network [OSTI]

    Ah Young, AP; Koehl, A; Cascio, D; Egea, PF

    2015-01-01T23:59:59.000Z

    falciparum: Targeting protein folding and secretion forfalciparum: targeting protein folding and secretion for

  15. Chamber and target technology development for inertial fusion energy

    SciTech Connect (OSTI)

    Abdou, M; Besenbruch, G; Duke, J; Forman, L; Goodin, D; Gulec, K; Hoffer, J; Khater, H; Kulcinsky, G; Latkowski, J F; Logan, B G; Margevicious, B; Meier, W R; Moir, R W; Morley, N; Nobile, A; Payne, S; Peterson, P F; Peterson, R; Petzoldt, R; Schultz, K; Steckle, W; Sviatoslavsky, L; Tillack, M; Ying, A

    1999-04-07T23:59:59.000Z

    Fusion chambers and high pulse-rate target systems for inertial fusion energy (IFE) must: regenerate chamber conditions suitable for target injection, laser propagation, and ignition at rates of 5 to 10 Hz; extract fusion energy at temperatures high enough for efficient conversion to electricity; breed tritium and fuel targets with minimum tritium inventory; manufacture targets at low cost; inject those targets with sufficient accuracy for high energy gain; assure adequate lifetime of the chamber and beam interface (final optics); minimize radioactive waste levels and annual volumes; and minimize radiation releases under normal operating and accident conditions. The primary goal of the US IFE program over the next four years (Phase I) is to develop the basis for a Proof-of-Performance-level driver and target chamber called the Integrated Research Experiment (IRE). The IRE will explore beam transport and focusing through prototypical chamber environment and will intercept surrogate targets at high pulse rep-rate. The IRE will not have enough driver energy to ignite targets, and it will be a non-nuclear facility. IRE options are being developed for both heavy ion and laser driven IFE. Fig. 1 shows that Phase I is prerequisite to an IRE, and the IRE plus NIF (Phase II) is prerequisite to a high-pulse rate. Engineering Test Facility and DEMO for IFE, leading to an attractive fusion power plant. This report deals with the Phase-I R&D needs for the chamber, driver/chamber interface (i.e., magnets for accelerators and optics for lasers), target fabrication, and target injection; it is meant to be part of a more comprehensive IFE development plan which will include driver technology and target design R&D. Because of limited R&D funds, especially in Phase I, it is not possible to address the critical issues for all possible chamber and target technology options for heavy ion or laser fusion. On the other hand, there is risk in addressing only one approach to each technology option. Therefore, in the following description of these specific feasibility issues, we try to strike a balance between narrowing the range of recommended R&D options to minimize cost, and keeping enough R&D options to minimize risk.

  16. Vacuum Predictions and Measurements for an Internal Pellet Target

    E-Print Network [OSTI]

    Lehmann, I; Friden, C J; Norman, G; Ekstrm, C; Johansson, T; Wiedner, U; Lehmann, Inti; Nordhage, Orjan; Friden, Carl-Johan; Norman, Gunar; Ekstrom, Curt; Johansson, Tord; Wiedner, Ulrich

    2007-01-01T23:59:59.000Z

    Measurements with low Z targets at internal experiments typically imply a gas load which deteriorates the ring vacuum. Future experiments need reliable estimates for the expected vacuum conditions in order to design 4-pi detectors closely surrounding the interaction area. We present a method for the calculation of the resulting vacuum of such a complex system using a Pellet Target. In order to test the method, a vacuum system with diagnostic tools has been set up and a Pellet Target was operated under realistic conditions. The results for the absolute vacuum agree within factors of two with the expected pressures.

  17. Vacuum Predictions and Measurements for an Internal Pellet Target

    E-Print Network [OSTI]

    Inti Lehmann; Orjan Nordhage; Carl-Johan Friden; Gunar Norman; Curt Ekstrom; Tord Johansson; Ulrich Wiedner

    2007-01-04T23:59:59.000Z

    Measurements with low Z targets at internal experiments typically imply a gas load which deteriorates the ring vacuum. Future experiments need reliable estimates for the expected vacuum conditions in order to design 4-pi detectors closely surrounding the interaction area. We present a method for the calculation of the resulting vacuum of such a complex system using a Pellet Target. In order to test the method, a vacuum system with diagnostic tools has been set up and a Pellet Target was operated under realistic conditions. The results for the absolute vacuum agree within factors of two with the expected pressures.

  18. Nail-like targets for laser plasma interaction experiments

    SciTech Connect (OSTI)

    Pasley, J; Wei, M; Shipton, E; Chen, S; Ma, T; Beg, F N; Alexander, N; Stephens, R B; MacPhee, A G; Hey, D; Pape, S L; Patel, P; Mackinnon, A J; Key, M H; Offermann, D; Link, A; Chowdhury, E; Van-Woerkom, L D; Freeman, R R

    2007-12-18T23:59:59.000Z

    The interaction of ultra-high power picosecond laser pulses with solid targets is of interest both for benchmarking the results of hybrid particle in cell (PIC) codes and also for applications to re-entrant cone guided fast ignition. We describe the construction of novel targets in which copper/titanium wires are formed into 'nail-like' objects by a process of melting and micromachining, so that energy can be reliably coupled to a 24 {micro}m diameter wire. An extreme-ultraviolet image of the interaction of the Titan laser with such a target is shown.

  19. Liner/target/CMU cassette design and fabrication

    SciTech Connect (OSTI)

    Griego, Jeffrey Randall [Los Alamos National Laboratory

    2011-01-07T23:59:59.000Z

    As part of an ongoing collaboration in pulsed power technology and condensed matter shock physics with RFNCNNIIEF, the initial design for the target and central measuring unit (CMU) for a high-pressure, high-precision ({approx}1 %), Hugoniot, equation of state (EOS) experiment is shown. VNIIEF would design and construct the disk explosive magnetic generator (DEMG) with peak currents {approx}100 MA, and cylindrical liner system with peak velocity {approx}10-20 km/s. LANL would design and construct the target and velocimetry diagnostic system. The initial mechanical design features a 2 cm diameter target system and a 1 cm diameter CMU with 32 lines of sight for PDV.

  20. Magnetized Target Fusion (MTF): Principles, Status, and International Collaboration

    SciTech Connect (OSTI)

    Kirkpatrick, R.C.

    1998-11-16T23:59:59.000Z

    Magnetized target fusion (MTF) is an approach to thermonuclear fusion that is intermediate between the two extremes of inertial and magnetic confinement. Target plasma preparation is followed by compression to fusion conditions. The use of a magnetic field to reduce electron thermal conduction and potentially enhance DT alpha energy deposition allows the compression rate to be drastically reduced relative to that for inertial confinement fusion. This leads to compact systems with target driver power and intensity requirements that are orders of magnitude lower than for ICF. A liner on plasma experiment has been proposed to provide a firm proof of principle for MTF.

  1. Inflation targeting in emerging countries: the exchange rate issues

    E-Print Network [OSTI]

    Reyes Altamirano, Javier Arturo

    2004-09-30T23:59:59.000Z

    The current discussion of Inflation Targeting (IT) in emerging economies deals with the effects that nominal exchange rate movements have on the overall inflation rate. The literature has focused in the analysis of the advantages and disadvantages...

  2. Engineered nanomedicine for myeloma and bone microenvironment targeting

    E-Print Network [OSTI]

    Swami, Archana

    Bone is a favorable microenvironment for tumor growth and a frequent destination for metastatic cancer cells. Targeting cancers within the bone marrow remains a crucial oncologic challenge due to issues of drug availability ...

  3. Kalman filter data assimilation: Targeting observations and parameter estimation

    SciTech Connect (OSTI)

    Bellsky, Thomas, E-mail: bellskyt@asu.edu; Kostelich, Eric J.; Mahalov, Alex [School of Mathematical and Statistical Sciences, Arizona State University, Tempe, Arizona 85287 (United States)] [School of Mathematical and Statistical Sciences, Arizona State University, Tempe, Arizona 85287 (United States)

    2014-06-15T23:59:59.000Z

    This paper studies the effect of targeted observations on state and parameter estimates determined with Kalman filter data assimilation (DA) techniques. We first provide an analytical result demonstrating that targeting observations within the Kalman filter for a linear model can significantly reduce state estimation error as opposed to fixed or randomly located observations. We next conduct observing system simulation experiments for a chaotic model of meteorological interest, where we demonstrate that the local ensemble transform Kalman filter (LETKF) with targeted observations based on largest ensemble variance is skillful in providing more accurate state estimates than the LETKF with randomly located observations. Additionally, we find that a hybrid ensemble Kalman filter parameter estimation method accurately updates model parameters within the targeted observation context to further improve state estimation.

  4. Proposals for Non-PGM Catalyst Target and Test Protocols

    Broader source: Energy.gov (indexed) [DOE]

    Fuel Cell Tech Team Proposals for Non-PGM catalyst target and test protocols FCTT (USCAR) Shinichi Hirano (co-chair), Tarek Abdel-Baset, Balsu Lakshmanan, David Masten, Mark...

  5. Treatment of biomass to obtain a target chemical

    DOE Patents [OSTI]

    Dunson, Jr., James B. (Newark, DE); Tucker, III, Melvin P. (Lakewood, CO); Elander, Richard T. (Evergreen, CO); Hennessey, Susan Marie (Avondale, PA)

    2010-08-24T23:59:59.000Z

    Target chemicals were produced using biocatalysts that are able to ferment sugars derived from treated biomass. Sugars were obtained by pretreating biomass under conditions of high solids and low ammonia concentration, followed by saccharification.

  6. The Internet as recommendation engine : implications of online behavioral targeting

    E-Print Network [OSTI]

    Smith-Grieco, Anthony Nicoll

    2010-01-01T23:59:59.000Z

    This thesis discusses the economic implications of Internet behavioral advertising, which targets ads to individuals based on extensive detailed data about the specific websites users have visited. Previous literature on ...

  7. Osteotropic Therapy via Targeted Layer-by-Layer Nanoparticles

    E-Print Network [OSTI]

    Morton, Stephen W.

    Current treatment options for debilitating bone diseases such as osteosarcoma, osteoporosis, and bone metastatic cancer are suboptimal and have low efficacy. New treatment options for these pathologies require targeted ...

  8. High density cluster jet target for storage ring experiments

    E-Print Network [OSTI]

    Alexander Tschner; Esperanza Khler; Hans-Werner Ortjohann; Alfons Khoukaz

    2011-11-02T23:59:59.000Z

    The design and performance of a newly developed cluster jet target installation for hadron physics experiments are presented which, for the first time, is able to generate a hydrogen cluster jet beam with a target thickness of above $10^{15}\\,\\mathrm{atoms/cm}^2$ at a distance of two metres behind the cluster jet nozzle. The properties of the cluster beam and of individual clusters themselves are studied at this installation. Special emphasis is placed on measurements of the target beam density as a function of the relevant parameters as well as on the cluster beam profiles. By means of a time-of-flight setup, measurements of the velocity of single clusters and velocity distributions were possible. The complete installation, which meets the requirements of future internal fixed target experiments at storage rings, and the results of the systematic studies on hydrogen cluster jets are presented and discussed.

  9. Influence of the Target - Density Effects on Electron - Capture Processes

    SciTech Connect (OSTI)

    Tolstikhina, I.Yu.; Shevelko, V.P. [P.N.Lebedev Physical Institute, 119991, Moscow (Russian Federation)

    2004-12-01T23:59:59.000Z

    The influence of the target density on the electron-capture (EC) processes in collisions of fast ions with atoms and molecules is considered. The partial EC cross sections {sigma}n on the principal quantum number n of the scattered projectile, as well as the total {sigma}tot values are calculated for highly charged ions interacting with gaseous and solid targets in the energy range of E = 100 keV/amu to 10 MeV/amu. It is shown that with the target density increasing, the population of the excited states of the scattered projectiles, formed via the EC channel, is suppressed due to projectile ionization by the target particles and, as a result, the effective EC cross sections drastically decrease.

  10. Ion beam sputter target and method of manufacture

    DOE Patents [OSTI]

    Higdon, Clifton; Elmoursi, Alaa A.; Goldsmith, Jason; Cook, Bruce; Blau, Peter; Jun, Qu; Milner, Robert

    2014-09-02T23:59:59.000Z

    A target for use in an ion beam sputtering apparatus made of at least two target tiles where at least two of the target tiles are made of different chemical compositions and are mounted on a main tile and geometrically arranged on the main tile to yield a desired chemical composition on a sputtered substrate. In an alternate embodiment, the tiles are of varied thickness according to the desired chemical properties of the sputtered film. In yet another alternate embodiment, the target is comprised of plugs pressed in a green state which are disposed in cavities formed in a main tile also formed in a green state and the assembly can then be compacted and then sintered.

  11. Free-Electron Laser Targets Fat | Jefferson Lab

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Free-Electron Laser Targets Fat April 10, 2006 Free-Electron Laser Scientists Rox Anderson, right, and Free-Electron Laser Scientist Steve Benson, left, discuss laser beam...

  12. Designer Proteins Target Epstein-Barr-Virus-Associated Cancer

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Designer Proteins Target Epstein-Barr-Virus-Associated Cancer Print Immortality is not a good thing for cells, and in fact, cells will destroy themselves in a process called...

  13. Topo II: An Enzyme Target for Antibacterial and Cancer Drugs

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Topo II: An Enzyme Target for Antibacterial and Cancer Drugs Print The veil has finally been lifted on an enzyme that is critical to the process of DNA transcription and...

  14. ams graphite target: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    OF THE BNL, in the first phase of the E951 experiment, graphite and carbon-carbon composite targets were exposed to the AGS materials selected for the experiment are ATJ...

  15. antibodies targeting cancer: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of an NF-B responsive element (pNF-B- Luc) encapsulated in a PRb peptide functionalized stealth targeted systems. In addition, we constructed a novel cancer therapeutic plasmid...

  16. Condition-Based Maintenance via Simulation and a Targeted Bayesian

    E-Print Network [OSTI]

    Ben-Gal, Irad E.

    malfunctioning. Accordingly, it is essential to undertake an effective preventive maintenance (PM) policyCondition-Based Maintenance via Simulation and a Targeted Bayesian Network Metamodel Aviv Gruber, Israel ABSTRACT Condition-based maintenance (CBM) is increasingly applied to operational systems

  17. assays targeting formyltetrahydrofolate: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Tovesson, F; Towell, D; Towell, R S; Watson, S; Wendt, B; Wood, L 2013-01-01 34 MECO Production Target Developments Physics Websites Summary: channel & thin containment tube costs...

  18. Prototype Spallation Neutron Source Rotating Target Assembly Final Test Report

    SciTech Connect (OSTI)

    McManamy, Thomas J [ORNL; Graves, Van [Oak Ridge National Laboratory (ORNL); Garmendia, Amaia Zarraoa [IDOM Bilbao; Sorda, Fernando [ESS Bilbao; Etxeita, Borja [IDOM Bilbao; Rennich, Mark J [ORNL

    2011-01-01T23:59:59.000Z

    A full-scale prototype of an extended vertical shaft, rotating target assembly based on a conceptual target design for a 1 to 3-MW spallation facility was built and tested. Key elements of the drive/coupling assembly implemented in the prototype include high integrity dynamic face seals, commercially available bearings, realistic manufacturing tolerances, effective monitoring and controls, and fail-safe shutdown features. A representative target disk suspended on a 3.5 meter prototypical shaft was coupled with the drive to complete the mechanical tests. Successful operation for 5400 hours confirmed the overall mechanical feasibility of the extended vertical shaft rotating target concept. The prototype system showed no indications of performance deterioration and the equipment did not require maintenance or relubrication.

  19. Hydrodynamic instabilities in beryllium targets for the National Ignition Facility

    SciTech Connect (OSTI)

    Yi, S. A., E-mail: austinyi@lanl.gov; Simakov, A. N.; Wilson, D. C.; Olson, R. E.; Kline, J. L.; Batha, S. H. [Los Alamos National Laboratory, P.O. Box 1663, Los Alamos, New Mexico 87545 (United States); Clark, D. S.; Hammel, B. A.; Milovich, J. L.; Salmonson, J. D.; Kozioziemski, B. J. [Lawrence Livermore National Laboratory, P.O. Box 808, Livermore, California 94551 (United States)

    2014-09-15T23:59:59.000Z

    Beryllium ablators offer higher ablation velocity, rate, and pressure than their carbon-based counterparts, with the potential to increase the probability of achieving ignition at the National Ignition Facility (NIF) [E. I. Moses et al., Phys. Plasmas 16, 041006 (2009)]. We present here a detailed hydrodynamic stability analysis of low (NIF Revision 6.1) and high adiabat NIF beryllium target designs. Our targets are optimized to fully utilize the advantages of beryllium in order to suppress the growth of hydrodynamic instabilities. This results in an implosion that resists breakup of the capsule, and simultaneously minimizes the amount of ablator material mixed into the fuel. We quantify the improvement in stability of beryllium targets relative to plastic ones, and show that a low adiabat beryllium capsule can be at least as stable at the ablation front as a high adiabat plastic target.

  20. The Cost of Kyoto Protocol Targets: The Case of Japan

    E-Print Network [OSTI]

    Paltsev, Sergey.

    This paper applies the MIT Emissions Prediction and Policy Analysis (EPPA) model to analysis of the cost of the Kyoto Protocol targets, with a special focus on Japan. The analysis demonstrates the implications of the use ...

  1. A Key Target for Diabetes Drugs | Advanced Photon Source

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    2001 | 2000 | 1998 | Subscribe to APS Science Highlights rss feed A Key Target for Diabetes Drugs JULY 26, 2013 Bookmark and Share The structure of the human glucagon receptor,...

  2. Targeting the tight junction : immunotherapy of colon cancer

    E-Print Network [OSTI]

    Ackerman, Margaret E

    2010-01-01T23:59:59.000Z

    A33 is a cell surface glycoprotein of colon epithelium with a long clinical history as a target in antibody-based cancer therapy. Despite being present in normal colon, radio-labeled antibodies against A33 are selectively ...

  3. Proceedings of the twelfth target fabrication specialists` meeting

    SciTech Connect (OSTI)

    NONE

    1999-04-01T23:59:59.000Z

    Research in fabrication for inertial confinement fusion (ICF) comprises at least three broad categories: targets for high energy density physics on existing drivers, ignition capsule fabrication, and cryogenic fuel layer formation. The latter two are being pursued primarily for the National Ignition Facility (NIF). Scientists from over 14 laboratories, universities, and businesses contributed over 100 papers on all aspects of ICF target fabrication. The NIF is well along in construction and photos of poured concrete and exposed steel added to the technical excitement. It was clear from the meeting that there has been significant progress toward the fabrication of an ignition target for NIF and that new techniques are resulting in higher quality targets for high energy density research.

  4. Heat Exchanger Network Targeting, Design and Analysis: The MIDAS Package

    E-Print Network [OSTI]

    Barton, I.; Jones, D. H.; Smith, G. J.

    are: o Improved utility targeting for constrained problems and wide range utilities. . o Advanced heat exchanger network area targeting. o Optimization of temperature driving forces for minimum total cost. o Automated HEN design using a... counter current conditions. 2. Finite temperature driving forces are required for heat transfer in any real system~ A minimum driving force of l'ITmln is assumed to prevail within the network, i.e. a stream giving up heat (said to be "hot...

  5. In vivo filtering of in vitro MyoD target data: An approach for identification of biologically relevant novel downstream targets of

    E-Print Network [OSTI]

    Golbeck, Jennifer

    relevant novel downstream targets of transcription factors. Po Zhao1 , Jinwook Seo2 , Zuyi Wang3 , Yue Wang of downstream targets of MyoD, where a published set of candidate targets from a well-controlled in vitro a downstream target promoter motif, called the "E-box", that share the consensus sequence of CANNTG. Most basic

  6. Metrology Challenges for High Energy Density Science Target Manufacture

    SciTech Connect (OSTI)

    Seugling, R M; Bono, M J; Davis, P

    2009-02-19T23:59:59.000Z

    Currently, High Energy Density Science (HEDS) experiments are used to support and qualify predictive physics models. These models assume ideal conditions such as energy (input) and device (target) geometry. The experiments rely on precision targets constructed from components with dimensions in the millimeter range, while having micrometer-scale, functional features, including planar steps, sine waves, and step-joint geometry on hemispherical targets. Future target designs will likely have features and forms that rival or surpass current manufacturing and characterization capability. The dimensional metrology of these features is important for a number of reasons, including qualification of sub-components prior to assembly, quantification of critical features on the as-built assemblies and as a feedback mechanism for fabrication process development. Variations in geometry from part to part can lead to functional limitations, such as unpredictable instabilities during an experiment and the inability to assemble a target from poorly matched sub-components. Adding to the complexity are the large number and variety of materials, components, and shapes that render any single metrology technique difficult to use with low uncertainty. Common materials include metal and glass foams, doped transparent and opaque plastics and a variety of deposited and wrought metals. A suite of metrology tools and techniques developed to address the many critical issues relevant to the manufacture of HEDS targets including interferometry, x-ray radiography and contact metrology are presented including two sided interferometry for absolute thickness metrology and low force probe technology for micrometer feature coordinate metrology.

  7. Final report SI 08-SI-004: Fusion application targets

    SciTech Connect (OSTI)

    Biener, J; Kucheyev, S O; Wang, M Y; Dawedeit, C; Worsley, M A; Kim, S H; Walton, C; Gilmer, G; Zepeda-Ruiz, L; Chernov, A A; Lee, J I; Willey, T M; Biener, M M; van Buuren, T; Wu, K J; Satcher, J H; Hamza, A V

    2010-12-03T23:59:59.000Z

    Complex target structures are necessary to take full advantage of the unique laboratory environment created by inertial confinement fusion experiments. For example, uses-of-ignition targets that contain a thin layer of a low density nanoporous material inside a spherical ablator shell allow placing dopants in direct contact with the DT fuel. The ideal foam for this application is a low-density hydrocarbon foam that is strong enough to survive wetting with cryogenic hydrogen, and low enough in density (density less than {approx}30 mg/cc) to not reduce the yield of the target. Here, we discuss the fabrication foam-lined uses-of-ignition targets, and the development of low-density foams that can be used for this application. Much effort has been directed over the last 20 years toward the development of spherical foam targets for direct-drive and fast-ignition experiments. In these targets, the spherical foam shell is used to define the shape of the cryogenic DT fuel layer, or acts as a surrogate to simulate the cryogenic fuel layer. These targets are fabricated from relatively high-density aerogels (>100 mg/cc) and coated with a few micron thick permeation barrier. With exception of the above mentioned fast ignition targets, the wall of these targets is typically larger than 100 microns. In contrast, the fusion application targets for indirect-drive experiments on NIF will require a much thinner foam shell surrounded by a much thicker ablator shell. The design requirements for both types of targets are compared in Table 1. The foam shell targets for direct-drive experiments can be made in large quantities and with reasonably high yields using an encapsulation technique pioneered by Takagi et al. in the early 90's. In this approach, targets are made by first generating unsupported foam shells using a triple-orifice droplet generator, followed by coating the dried foam shells with a thin permeation barrier. However, this approach is difficult, if not impossible, to transfer to the lower density and thinner wall foam shells required for indirect-drive uses-of-ignition targets for NIF that then would have to be coated with an at least hundred-micron-thick ablator film. So far, the thinnest shells that have been fabricated using the triple-orifice-droplet generator technique had a wall thickness of {approx}20 microns, but despite of being made from a higher-density foam formulation, the shells were mechanically very sensitive, difficult to dry, and showed large deviations from roundness. We thus decided to explore a different approach based on using prefabricated thick-walled spherical ablator shells as templates for the thin-walled foam shell. As in the case of the above mentioned encapsulation technique, the foam is made by sol-gel chemistry. However, our approach removes much the requirements on the mechanical stability of the foam shell as the foam shell is never handled in its free-standing form, and promises superior ablator uniformity and surface roughness. As discussed below, the success of this approach depends strongly on the availability of suitable aerogel chemistries (ideally pure hydrocarbon (CH)-based systems) with suitable rheological properties (high viscosity and high modulus near the gel point) that produce low-density and mechanically strong foams.

  8. Review of High Power Proton Target Challenges Heat Removal and Thermal `Shock'

    E-Print Network [OSTI]

    McDonald, Kirk

    body Graphite (ToyoTanso IG-43) Helium cooling Graphite to titanium diffusion bond Ti-6Al-4V tube Peripherally cooled cylinder Water cooled gold target Radiation cooled tungsten target ~940 mm Titanium target

  9. Method for distinguishing multiple targets using time-reversal acoustics

    DOE Patents [OSTI]

    Berryman, James G.

    2004-06-29T23:59:59.000Z

    A method for distinguishing multiple targets using time-reversal acoustics. Time-reversal acoustics uses an iterative process to determine the optimum signal for locating a strongly reflecting target in a cluttered environment. An acoustic array sends a signal into a medium, and then receives the returned/reflected signal. This returned/reflected signal is then time-reversed and sent back into the medium again, and again, until the signal being sent and received is no longer changing. At that point, the array has isolated the largest eigenvalue/eigenvector combination and has effectively determined the location of a single target in the medium (the one that is most strongly reflecting). After the largest eigenvalue/eigenvector combination has been determined, to determine the location of other targets, instead of sending back the same signals, the method sends back these time reversed signals, but half of them will also be reversed in sign. There are various possibilities for choosing which half to do sign reversal. The most obvious choice is to reverse every other one in a linear array, or as in a checkerboard pattern in 2D. Then, a new send/receive, send-time reversed/receive iteration can proceed. Often, the first iteration in this sequence will be close to the desired signal from a second target. In some cases, orthogonalization procedures must be implemented to assure the returned signals are in fact orthogonal to the first eigenvector found.

  10. Processing and Disposition of Special Actinide Target Materials - 13138

    SciTech Connect (OSTI)

    Robinson, Sharon M.; Patton, Brad D. [Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, TN 37831 (United States)] [Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, TN 37831 (United States); Allender, Jeffrey S. [Savannah River National Laboratory (United States)] [Savannah River National Laboratory (United States)

    2013-07-01T23:59:59.000Z

    The Department of Energy (DOE) manages an inventory of materials that contains a range of long-lived radioactive isotopes that were produced from the 1960's through the 1980's by irradiating targets in high-flux reactors at the Savannah River Site (SRS) to produce special heavy isotopes for DOE programmatic use, scientific research, and industrial and medical applications. Among the products were californium-252, heavy curium (including Cm-246 through Cm-248), and plutonium-242 and -244. Many of the isotopes are still in demand today, and they can be recovered from the remaining targets previously irradiated at SRS or produced from the recovered isotopes. Should the existing target materials be discarded, the plutonium (Pu) and curium (Cm) isotopes cannot be replaced readily with existing production sources. Some of these targets are stored at SRS, while other target material is stored at Oak Ridge National Laboratory (ORNL) at several stages of processing. The materials cannot be stored in their present form indefinitely. Their long-term management involves processing items for beneficial use and/or for disposition, using storage and process facilities at SRS and ORNL. Evaluations are under way for disposition options for these materials, and demonstrations of improved flow sheets to process the materials are being conducted at ORNL and the Savannah River National Laboratory (SRNL). The disposition options and a management evaluation process have been developed. Processing demonstrations and evaluations for these unique materials are under way. (authors)

  11. Active target studies of the ?p-process at CRIB

    SciTech Connect (OSTI)

    Kahl, D.; Yamaguchi, H.; Michimasa, S.; Nakao, T.; Ota, S.; Tokieda, H. [Center for Nuclear Study, Graduate School of Science, The University of Tokyo (Japan); Hashimoto, T. [Center for Nuclear Study, Graduate School of Science, The University of Tokyo, Japan and Research Center for Nuclear Physics (RCNP), Osaka University (Japan); Duy, N. N.; Khiem, L. H. [Institute of Physics (Viet Nam); Kubono, S. [Center for Nuclear Study, Graduate School of Science,Tthe University of Tokyo (Japan); RIKEN (The Institute of Physical and Chemical Research) (Japan); Institute of Modern Physics, Chinese Academy of Sciences (China); Binh, D. N. [Center for Nuclear Study, Graduate School of Science, The University of Tokyo, Japan and Institute of Physics (Viet Nam); Chen, A. A. [Department of Physics and Astronomy, McMaster University (Canada); Cherubini, S. [Department of Physics, University of Catania and INFN (Italy); Hayakawa, S. [Center for Nuclear Study, Graduate School of Science, The University of Tokyo, Japan and Department of Physics, University of Catania and INFN (Italy); He, J. J.; Zhang, L. Y. [Institute of Modern Physics, Chinese Academy of Sciences (China); Ishiyama, H. [Institute of Particle and Nuclear Studies, High Energy Accelerator Research Organization (KEK) (Japan); Iwasa, N.; Yamada, T. [Department of Physics, Tohoku University (Japan); Kwon, Y. K. [Institute for Basic Science (Korea, Republic of); and others

    2014-05-02T23:59:59.000Z

    The ?p-process is a sequence of (?, p)(p, ?) reactions important to the nuclear trajectory to higher masses in type I X-ray bursts. Specifically, the ?p-process is schematically pure helium-burning, and thus unlike pure hydrogen-burning processes, does not require slow ?{sup +} decays. Explosive helium burning is responsible for the observed short rise-times of X-ray bursts but ultimately gives way to the rp-process as the Coulomb barrier increases. Because the stellar reaction rates of these (?, p) reactions are poorly known over the relevant astrophysical energies, we performed systematic studies of the {sup 18}Ne(?,p), {sup 22}Mg(?,p) and {sup 30}S(?,p) reactions at the Center for Nuclear Study (CNS) low-energy radioactive ion beam separator, called CRIB. We produce the radioactive beams in-flight and scan the center-of-mass energy down into the Gamow Window using a thick target in inverse kinematics. The helium target gas also serves as part of the detector system, an active target, which was newly designed for these measurements. The active target, which uses gas electron multiplier (GEM) foils, allows for higher beam injection rates than previous multi-sampling and tracking proportional counters (MSTPC). We present a summary of our recent results from these active target experiments at CRIB.

  12. Method and apparatus for optimized sampling of volatilizable target substances

    DOE Patents [OSTI]

    Lindgren, Eric R.; Phelan, James M.

    2004-10-12T23:59:59.000Z

    An apparatus for capturing, from gases such as soil gas, target analytes. Target analytes may include emanations from explosive materials or from residues of explosive materials. The apparatus employs principles of sorption common to solid phase microextraction, and is best used in conjunction with analysis means such as a gas chromatograph. To sorb target analytes, the apparatus functions using various sorptive structures to capture target analyte. Depending upon the embodiment, those structures may include a capillary tube including an interior surface on which sorptive material (similar to that on the surface of a SPME fiber) is supported (along with means for moving gases through the capillary tube so that the gases come into close proximity to the sorptive material). In one disclosed embodiment, at least one such sorptive structure is associated with an enclosure including an opening in communication with the surface of a soil region potentially contaminated with buried explosive material such as unexploded ordnance. Emanations from explosive materials can pass into and accumulate in the enclosure where they are sorbed by the sorptive structures. Also disclosed is the use of heating means such as microwave horns to drive target analytes into the soil gas from solid and liquid phase components of the soil.

  13. Method and apparatus for optimized sampling of volatilizable target substances

    DOE Patents [OSTI]

    Lindgren, Eric R. (Albuquerque, NM); Phelan, James M. (Bosque Farms, NM)

    2002-01-01T23:59:59.000Z

    An apparatus for capturing, from gases such as soil gas, target analytes. Target analytes may include emanations from explosive materials or from residues of explosive materials. The apparatus employs principles of sorption common to solid phase microextraction, and is best used in conjunction with analysis means such as a gas chromatograph. To sorb target analytes, the apparatus functions using various sorptive structures to capture target analyte. Depending upon the embodiment, those structures may include 1) a conventional solid-phase microextraction (SPME) fiber, 2) a SPME fiber suspended in a capillary tube (with means provided for moving gases through the capillary tube so that the gases come into close proximity to the suspended fiber), and 3) a capillary tube including an interior surface on which sorptive material (similar to that on the surface of a SPME fiber) is supported (along with means for moving gases through the capillary tube so that the gases come into close proximity to the sorptive material). In one disclosed embodiment, at least one such sorptive structure is associated with an enclosure including an opening in communication with the surface of a soil region potentially contaminated with buried explosive material such as unexploded ordnance. Emanations from explosive materials can pass into and accumulate in the enclosure where they are sorbed by the sorptive structures. Also disclosed is the use of heating means such as microwave horns to drive target analytes into the soil gas from solid and liquid phase components of the soil.

  14. Proceedings of the Tungsten Workshop for Hard Target Weapons Program

    SciTech Connect (OSTI)

    Mackiewicz-Ludtka, G.; Hayden, H.W.; Davis, R.M.

    1995-06-01T23:59:59.000Z

    The purpose of this meeting was to review and exchange information and provide technical input for improving technologies relevant to the Hard Target Weapons Program. This workshop was attended by representatives from 17 organizations, including 4 Department of Defense (DoD) agencies, 8 industrial companies, and 5 laboratories within DOE. Hard targets are defined as reinforced underground structures that house enemy forces, weapon systems, and support equipment. DOE-ORO and Martin Marietta Energy Systems, Inc. (Energy Systems) have been involved in advanced materials research and development (R&D) for several DOE and DoD programs. These programs are conducted in close collaboration with Eglin AFB, Department of the Army`s Picatinny Arsenal, and other DoD agencies. As part of this ongoing collaboration, Eglin AFB and Oak Ridge National Laboratory planned and conducted this workshop to support the Hard Target Weapons Program. The objectives of this workshop were to (1) review and identify the technology base that exists (primarily due to anti-armor applications) and assess the applicability of this technology to the Hard Target Weapons Program requirements; (2) determine future directions to establish the W materials, processing, and manufacturing technologies suitable for use in fixed, hard target penetrators; and (3) identify and prioritize the potential areas for technical collaboration among the participants.

  15. Automating efficiency-targeted approximations in modelling and simulation tools: dynamic decoupling and mixed-mode

    E-Print Network [OSTI]

    Como, Giacomo

    Automating efficiency-targeted approximations in modelling and simulation tools: dynamic decoupling (classical) efficiency-targeted approximation tech- niques, within a unified framework. Some application

  16. Construction of a rice glycoside hydrolase phylogenomic database and identification of targets for biofuel research.

    E-Print Network [OSTI]

    Sharma, Rita; Cao, Peijian; Jung, Ki-Hong; Sharma, Manoj K; Ronald, Pamela C

    2013-01-01T23:59:59.000Z

    fication of targets for biofuel research. Front. Plant Sci.identification of targets for biofuel research Rita Sharmawall modification. Keywords: biofuel, cell wall, database,

  17. apoptosis-related plzf target: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Replacement of the target module was accomplished using only remote handling tooling and procedures (hands meter of high density concrete The Target Service Bay is...

  18. anti-invasive multi-integrin targeting: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Replacement of the target module was accomplished using only remote handling tooling and procedures (hands meter of high density concrete The Target Service Bay is...

  19. Large Scale Computing and Storage Requirements for Fusion Energy Sciences: Target 2017

    E-Print Network [OSTI]

    Gerber, Richard

    2014-01-01T23:59:59.000Z

    Requirements for Fusion Energy Sciences: Target 2017 Requirements for Fusion Energy Sciences: Target and Context DOEs Fusion Energy Sciences program

  20. Targeting Net Zero Energy at Marine Corps Base Kaneohe Bay, Hawaii...

    Broader source: Energy.gov (indexed) [DOE]

    Targeting Net Zero Energy at Marine Corps Base Kaneohe Bay, Hawaii: Assessment and Recommendations Targeting Net Zero Energy at Marine Corps Base Kaneohe Bay, Hawaii: Assessment...

  1. Spectral Control of Emission from Tin Doped Targets for Extreme Ultraviolet Lithography

    E-Print Network [OSTI]

    2006-01-01T23:59:59.000Z

    control of emissions from tin doped targets for extremearray (UTA) emission around 13.5 nm from solid density tinand tin doped foam targets. Extreme ultraviolet (EUV)

  2. antibody-opsonized target cells: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    51 Absorbed dose in target cell nuclei and dose conversion coefficient of radon progeny Biology and Medicine Websites Summary: Absorbed dose in target cell nuclei and...

  3. Radioactive targets for neutron-induced cross section measurements

    SciTech Connect (OSTI)

    Kronenberg, A. (Andreas); Bond, E. M. (Evelyn M.); Glover, S. E. (Samuel E.); Rundberg, R. S. (Robert S.); Vieira, D. J. (David J.); Esch, E. I. (Ernst-Ingo); Reifarth, R. (Rene); Ullmann, J. L. (John L.); Haight, Robert C.; Rochmann, D. (Dimitri)

    2004-01-01T23:59:59.000Z

    Measurements using radioactive targets are important for the determination of key reaction path ways associated with the synthesis of the elements in nuclear astrophysics (sprocess), advanced fuel cycle initiative (transmutation of radioactive waste), and stockpile stewardship. High precision capture cross-section measurements are needed to interpret observations, predict elemental or isotopical ratios, and unobserved abundances. There are two new detector systems that are presently being commissioned at Los Alamos National Laboratory for very precise measurements of (n,{gamma}) and (n,f) cross-sections using small quantities of radioactive samples. DANCE (Detector for Advanced Neutron-Capture Experiments), a 4 {pi} gamma array made up of 160 BaF{sub 2} detectors, is designed to measure neutron capture cross-sections of unstable nuclei in the low-energy range (thermal to {approx}500 keV). The high granularity and high detection efficiency of DANCE, combined with the high TOF-neutron flux available at the Lujan Center provides a versatile tool for measuring many important cross section data using radioactive and isotopically enriched targets of about 1 milligram. Another powerful instrument is the Lead-slowing down spectrometer (LSDS), which will enable the measurement of neutron-induced fission cross-section of U-235m and other short-lived actinides in a energy range from 1-200 keV with sample sizes down to 10 nanograms. Due to the short half-life of the U-235m isomer (T{sub 1/2} = 26 minutes), the samples must be rapidly and repeatedly extracted from its {sup 239}Pu parent. Since {sup 239}Pu is itself highly fissile, the separation must not only be rapid, but must also be of very high purity (the Pu must be removed from the U with a decontamination factor >10{sup 12}). Once extracted and purified, the {sup 235m}U isomer would be electrodeposited on solar cells as a fission detector and placed within the LSDS for direct (n,f) cross section measurements. The production of radioactive targets of a few milligrams will be described as well as the containment for safe handling of these targets at the Lujan Center at LANSCE. To avoid any contamination, the targets are electrochemically fixed onto thin Ti foils and two foils are placed back to back to contain the radioactive material within. This target sandwich is placed in a cylinder made of aluminum with thin translucent windows made of Kapton. Actinides targets, such as {sup 234,235,236,238}U, {sup 237}Np, and {sup 239}Pu are prepared by electrodeposition or molecular plating techniques. Target thicknesses of 1-2 mg/cm{sup 2} with sizes of 1 cm{sup 2} or more have been made. Other targets will be fabricated from separation of irradiated isotopically enriched targets, such as {sup 155}Eu from {sup 154}Sm,{sup 171}Tm from {sup 170}Er, and {sup 147}Pm from {sup 146}Nd, which has been irradiated in the high flux reactor at ILL, Grenoble. A radioactive sample isotope separator (RSIS) is in the process of being commissioned for the preparation of other radioactive targets. A brief summary of these experiments and the radioactive target preparation technique will be given.

  4. Proton radiography of a shock-compressed target

    SciTech Connect (OSTI)

    Ravasio, A.; Benuzzi-Mounaix, A.; Loupias, B.; Ozaki, N.; Vinci, T.; Koenig, M. [Laboratoire pour l'Utilisation des Lasers Intenses, UMR 7605, CNRS-CEA-Universite Paris VI-Ecole Polytechnique, 91128 Palaiseau Cedex (France); Romagnani, L.; Cecchetti, C.; Borghesi, M. [School of Mathematics and Physics, The Queen's University of Belfast, Belfast BT7 INN (United Kingdom); Le Pape, S.; Hicks, D.; MacKinnon, A.; Park, H. S.; Patel, P. [Lawrence Livermore National Laboratory, Livermore, California 94550 (United States); Batani, D.; Dezulian, R. [Dipartimento di Fisica G. Occhialini, Universita di Milano-Bicocca, Piazza Della Scienze 3, 20126 Milano (Italy); Boehly, T. [Laboratory for Laser Energetics, University of Rochester, Rochester, New York 14623 (United States); Gremillet, L.; Henry, E. [CEA, DAM, DIF, F-91297 Arpajon Cedex (France); Schiavi, A. [Department of Energetics, University of Rome 'La Sapienza' Rome (Italy)

    2010-07-15T23:59:59.000Z

    In this paper we report on the radiography of a shock-compressed target using laser produced proton beams. A low-density carbon foam target was shock compressed by long pulse high-energy laser beams. The shock front was transversally probed with a proton beam produced in the interaction of a high intensity laser beam with a gold foil. We show that from radiography data, the density profile in the shocked target can be deduced using Monte Carlo simulations. By changing the delay between long and short pulse beams, we could probe different plasma conditions and structures, demonstrating that the details of the steep density gradient can be resolved. This technique is validated as a diagnostic for the investigation of warm dense plasmas, allowing an in situ characterization of high-density contrasted plasmas.

  5. Target Selection for the LBTI Exozodi Key Science Program

    E-Print Network [OSTI]

    Weinberger, Alycia J; Kennedy, Grant M; Roberge, Aki; Defrre, Denis; Hinz, Philip M; Millan-Gabet, Rafael; Rieke, George; Bailey, Vanessa P; Danchi, William C; Haniff, Chris; Mennesson, Bertrand; Serabyn, Eugene; Skemer, Andrew J; Stapelfeldt, Karl R; Wyatt, Mark C

    2015-01-01T23:59:59.000Z

    The Hunt for Observable Signatures of Terrestrial planetary Systems (HOSTS) on the Large Binocular Telescope Interferometer will survey nearby stars for faint emission arising from ~300 K dust (exozodiacal dust), and aims to determine the exozodiacal dust luminosity function. HOSTS results will enable planning for future space telescopes aimed at direct spectroscopy of habitable zone terrestrial planets, as well as greater understanding of the evolution of exozodiacal disks and planetary systems. We lay out here the considerations that lead to the final HOSTS target list. Our target selection strategy maximizes the ability of the survey to constrain the exozodi luminosity function by selecting a combination of stars selected for suitability as targets of future missions and as sensitive exozodi probes. With a survey of approximately 50 stars, we show that HOSTS can enable an understanding of the statistical distribution of warm dust around various types of stars and is robust to the effects of varying levels ...

  6. Influence of target structure on film stress in WTi sputtering

    SciTech Connect (OSTI)

    Lo, C.F.; Wang, H.; Gilman, P. [Materials Research Corp., Orangeburg, NY (United States)

    1998-12-31T23:59:59.000Z

    In this report, the effect of sputtering target microstructure on the deposited film stress was investigated. By controlling the metallurgical process, two types of W-10wt%Ti target constituents, namely single-phase and multiple-phase WTi, were prepared. The former one was composed of W-rich ({beta}Ti,W) phase only, the latter one was with W, W-rich ({beta}Ti,W) and Ti-rich ({beta}Ti,W) phases. The stress of the films deposited on 12.7 cm diameter silicon oxide wafers from the single-phase target tends to be more compressive than that from the multiple-phase target. By increasing wafer temperature, the compressive stress was linearly decreased. In addition, the level of film stress was also affected by the film thickness and other sputtering parameters. To understand the causes for the differences in film stress between the multiple-phase and single-phase derived films, an evaluation of the film structure using a field-emission scanning electron microscope (FE-SEM) and mechanical testing using a nano-indentation instrument were performed. Finer domains with denser laminar structure were observed on the films deposited from the single-phase target. However, no significant difference in mechanical properties was found between these two from the nano-indentation measurements. It is envisioned that the more uniform solid solution between the W and Ti in the films obtained by sputtering the single-phase targets generates a higher compressive stress when deposited on the silicon oxide wafers resulting in a higher compressive stress.

  7. Interactive display system having a scaled virtual target zone

    DOE Patents [OSTI]

    Veligdan, James T.; DeSanto, Leonard

    2006-06-13T23:59:59.000Z

    A display system includes a waveguide optical panel having an inlet face and an opposite outlet face. A projector and imaging device cooperate with the panel for projecting a video image thereon. An optical detector bridges at least a portion of the waveguides for detecting a location on the outlet face within a target zone of an inbound light spot. A controller is operatively coupled to the imaging device and detector for displaying a cursor on the outlet face corresponding with the detected location of the spot within the target zone.

  8. Compressive Radar with Off-Grid and Extended Targets

    E-Print Network [OSTI]

    Fannjiang, Albert

    2012-01-01T23:59:59.000Z

    Compressed sensing (CS) schemes are proposed for monostatic as well as synthetic aperture radar (SAR) imaging of sparse targets with chirps. In particular, a simple method is developed to improve performance with off-grid targets. Tomographic formulation of spotlight SAR is analyzed by CS methods with several bases and under various bandwidth constraints. Performance guarantees are established via coherence bound and the restricted isometry property. CS analysis provides a fresh and clear perspective on how to optimize temporal and angular samplings for spotlight SAR.

  9. Nuclear target foil fabrication for the Romano Event

    SciTech Connect (OSTI)

    Weed, J.W.; Romo, J.G. Jr.; Griggs, G.E.

    1984-06-19T23:59:59.000Z

    The Vacuum Processes Lab, of LLNL's M.E. Dept. - Material Fabrication Division, was requested to provide 250 coated Parylene target foils for a nuclear physics experiment titled the ROMANO Event. Due to the developmental nature of some of the fabrication procedures, approximately 400 coated foils were produced to satisfy the event's needs. The foils were used in the experiment as subkilovolt x-ray, narrow band pass filters, and wide band ultraviolet filters. This paper is divided into three sections describing: (1) nuclear target foil fabrication, (2) Parylene substrate preparation and production, and (3) foil and substrate inspections.

  10. LIBRARY PARTITIONING FOR TARGET DETECTION IN JOINT CONTAMINATED SURFACE DETECTOR

    E-Print Network [OSTI]

    Adali, Tulay

    that is present from the given library. For a hypothesis testing problem, there are two types of statistical error in the given library present in the mixtures; Type II error, also known as a false negative, is the errorLIBRARY PARTITIONING FOR TARGET DETECTION IN JOINT CONTAMINATED SURFACE DETECTOR Wei Wang and T

  11. LA-UR-98-5674 Magnetized Target Fusion

    E-Print Network [OSTI]

    pinch formation techniques. The resulting FRC will then be translated into an aluminum liner using the MOQUI FRC code shows that the required plasma can be formed using conical theta pinch coils,4]. The CT plasma is the target, which we will implode using well-established liner technology developed

  12. Statistical Pattern Recognition Techniques for Target Differentiation using Infrared Sensor

    E-Print Network [OSTI]

    Barshan, Billur

    systems [1, 2, 3]. Dif- ferentiation is also important in industrial applications where different detector. These devices are inexpensive, practical, and widely available. The emitted light is reflected classifiers) for target differentiation. We provide a comparison of these approaches based on real data

  13. GLOBAL GLACIAL ISOSTATIC ADJUSTMENT: TARGET FIELDS FOR SPACE GEODESY

    E-Print Network [OSTI]

    Peltier, W. Richard

    GLOBAL GLACIAL ISOSTATIC ADJUSTMENT: TARGET FIELDS FOR SPACE GEODESY W.R. Peltier Department of Physics, University of Toronto, Toronto, Ontario, Canada M5S-1A7 peltier) and Sabadini and Peltier (1981) whose analysis was based upon the application of a homogeneous viscoelastic

  14. Target Ideas R. Palmer 2/10/01

    E-Print Network [OSTI]

    McDonald, Kirk

    on the assumption that the previous beam puls had fully disrupted the jet all the way back to the nozzle of filling from the jet. The drain would only be opened when emptying the contaiment for its removal. radii(cm) length (cm) Be Window Target containment Shielding Shielding Fe Fe Fe Fe 0 250 500 -50 -25 0 25 50 Drain

  15. Project-X Workshop 120 GeV Target

    E-Print Network [OSTI]

    McDonald, Kirk

    Project-X Workshop 120 GeV Target Summary ­ Workshop # 1 N. Simos, M. Martens #12;Project-X Workshop Challenges OVERVIEW Driven by 120 GeV/170 TP-per-spill · Short Term: 170 TPs/2us-spill (materials an existing 400 kW facility ­ Constraints #12;Project-X Workshop Presentations - Discussions · Engineering

  16. Targeting Net Zero Energy for Military Installations (Presentation)

    SciTech Connect (OSTI)

    Burman, K.

    2012-05-01T23:59:59.000Z

    Targeting Net Zero Energy for Military Installations in Kaneohe Bay, Hawaii. A net zero energy installation (NZEI) is one that produces as much energy from on-site renewable sources as it consumes. NZEI assessment provides a systematic approach to energy projects.

  17. Accelerator driven production of tritium: target and blanket design

    E-Print Network [OSTI]

    Ragusa, Jean Concetto

    1996-01-01T23:59:59.000Z

    investigated. The target designs in the heterogeneous systems were 1 / liquid lead, and 2/ layers of solid lead plates cooled by heavy water. The tritium breeding blanket assemblies contained either lithium oxide or molten fluorine salt with or without UF4...

  18. Cellubrevin-targeted Fluorescence Uncovers Heterogeneity in the Recycling Endosomes*

    E-Print Network [OSTI]

    Machen, Terry E.

    Cellubrevin-targeted Fluorescence Uncovers Heterogeneity in the Recycling Endosomes* (Received, University of California, Berkeley, California 94720-3200 The pH and trafficking of recycling endosomes have-enriched recycling endosomes (pHCb) and FITC-transferrin to measure the pH of transferrin- enriched recycling

  19. Mechanism of genotoxicity induced by targeted cytoplasmic irradiation

    E-Print Network [OSTI]

    process is largely unknown. METHODS: A microbeam that can target the cytoplasm of cells with high of extracellular signal-related kinase (ERK) pathway. CONCLUSION: We herein proposed a possible signalling pathway and that this process is mediated by free radicals (Wu et al, 1999). One of the most abundant oxidative lesions caused

  20. Targets for Neutrino Factories and Muon Colliders %%%%%%%%%%%%%%%&'())0

    E-Print Network [OSTI]

    McDonald, Kirk

    t is less than target radius r divided by speed of sound vsound, beam-induced pressure waves (thermal shock P (= force/area) given by P = E r r = EU C , where E is the modulus of elasticity. Kirk T. Mc

  1. Targets for Neutrino Factories and Muon Colliders ( ( ( ( ( ( ( ( ( ( ( ( ( (()1032546487

    E-Print Network [OSTI]

    McDonald, Kirk

    t is less than target radius r divided by speed of sound vsound, beam-induced pressure waves (thermal shock P (= force/area) given by P = E r r = EU C , where E is the modulus of elasticity. Kirk T. Mc

  2. EM Rockets Past Target for Donations to Stock Food Banks

    Broader source: Energy.gov [DOE]

    WASHINGTON, D.C. EM donated close to 50,000 pounds of non-perishable items to the Fourth Annual Feds Feed Families Campaign, easily surpassing its target of 19,120 pounds. All donations were delivered directly to food banks to provide goods to the needy.

  3. Uniformity of fuel target implosion in Heavy Ion Fusion

    E-Print Network [OSTI]

    Kawata, S; Suzuki, T; Karino, T; Barada, D; Ogoyski, A I; Ma, Y Y

    2015-01-01T23:59:59.000Z

    In inertial confinement fusion the target implosion non-uniformity is introduced by a driver beams' illumination non-uniformity, a fuel target alignment error in a fusion reactor, the target fabrication defect, et al. For a steady operation of a fusion power plant the target implosion should be robust against the implosion non-uniformities. In this paper the requirement for the implosion uniformity is first discussed. The implosion uniformity should be less than a few percent. A study on the fuel hotspot dynamics is also presented and shows that the stagnating plasma fluid provides a significant enhancement of vorticity at the final stage of the fuel stagnation. Then non-uniformity mitigation mechanisms of the heavy ion beam (HIB) illumination are also briefly discussed in heavy ion inertial fusion (HIF). A density valley appears in the energy absorber, and the large-scale density valley also works as a radiation energy confinement layer, which contributes to a radiation energy smoothing. In HIF a wobbling he...

  4. Molecular titration by MicroRNAs and target mimic inhibitors

    E-Print Network [OSTI]

    Ebert, Margaret S. (Margaret Sarah)

    2010-01-01T23:59:59.000Z

    MicroRNAs (miRNAs) are short, highly conserved non-coding RNA molecules that repress gene expression in a sequence-dependent manner. Each miRNA is predicted to target hundreds of genes, and a majority of protein-coding ...

  5. Multifunctional Polymeric Micelles as Cancer-Targeted, MRI-Ultrasensitive

    E-Print Network [OSTI]

    Gao, Jinming

    the micelle core. The presence of cRGD on the micelle surface resulted in the cancer-targeted delivery to rv 3, provide a unique core-shell architecture wherein the hy- drophobic core serves as a natural carrier.3-5 Sterically stabilized micelles by the PEG corona have shown prolonged blood circulation

  6. 100-F Target Analyte List Development for Soil

    SciTech Connect (OSTI)

    Ovink, R.

    2012-09-18T23:59:59.000Z

    This report documents the process used to identify source area target analytes in support of the 100-F Area remedial investigation/feasibility study (RI/FS) addendum to the Integrated 100 Area Remedial Investigation/Feasibility Study Work Plan (DOE/RL-2008-46, Rev. 0).

  7. NEW: Network-Enabled Electronic Warfare for Target

    E-Print Network [OSTI]

    Cheng, Xiuzhen "Susan"

    NEW: Network-Enabled Electronic Warfare for Target Recognition QILIAN LIANG University of Texas-enabled electronic warfare (NEW) is the development of modeling and simulation efforts that explore the advantages-enabled electronic warfare (NEW) is the form of electronic combat used in NCW. Focus is placed on a network

  8. Cooperative nanomaterial system to sensitize, target, and treat tumors

    E-Print Network [OSTI]

    Bhatia, Sangeeta

    as photother- mal antennas to specify tumor heating via remote near-infrared laser irradiation. We find that local tumor heating accelerates the recruitment of the second component: a targeted nanoparticle malignant tissues by converting external electromagnetic energy into heat (1­6). Furthermore, most

  9. A Search Model for Imperfectly Detected Targets Introduction

    E-Print Network [OSTI]

    : Figure 2 illustrates the background image. The upper region simulated the sky, the lower region simulated the sea. The target was a single pixel in the sky next to the sea with the same color as the sea. The stimuli were shown on a Samsung 910T LCD monitor in digital (DVI) mode. The luminance contrast

  10. Coverage Properties of the Target Area in Wireless Sensor Networks

    E-Print Network [OSTI]

    Zuyev, Sergei

    1 Coverage Properties of the Target Area in Wireless Sensor Networks Xiaoyun Li, Member, IEEE is developed for the probability of sensing coverage in a wireless sensor network with randomly deployed sensor examined. These results will have applications in planning and design tools for wireless sensor networks

  11. Probabilistic Detection of Mobile Targets in Heterogeneous Sensor Networks

    E-Print Network [OSTI]

    Poovendran, Radha

    , a surveillance system can be realized via fusion of data aggregated from various sensor modalities: infrared, CCD of detection can be quantified by evaluating the probability of detection by at least k sensors, where kProbabilistic Detection of Mobile Targets in Heterogeneous Sensor Networks Loukas Lazos Network

  12. Prolonging Network Lifetime for Target Coverage in Sensor Networks

    E-Print Network [OSTI]

    Liang, Weifa

    limits the network lifetime and impairs the network quality. To prolong the network lifetime, energy-efficiency network used for monitoring targets. One efficient method of reducing the energy consumption of sensors Department of Computer Science, The Australian National University Canberra, ACT 0200, Australia Abstract

  13. Fractalkine Targeting with a Receptor-Mimicking Peptide-Amphiphile

    E-Print Network [OSTI]

    Kokkoli, Efie

    . Kasinskas, Anastasia Mardilovich, and Ashish Garg Department of Chemical Engineering and Materials Science drug delivery systems driven by a strong need in clinical practice. Advances in materials science to the target tissue.2 Liposomes have been investigated extensively and long-circulating liposomes (stealth lipo

  14. Ion Channels as Promising Therapeutic Targets for Melanoma

    E-Print Network [OSTI]

    Paris-Sud XI, Universit de

    20 Ion Channels as Promising Therapeutic Targets for Melanoma Aurlie Chantme1, Marie Potier. During the last decade, the number of ion- channel types expressed in various cancers, including melanoma;Breakthroughs in Melanoma Research430 class of channels, water channels or aquaporins (AQP), allow water

  15. Linear Codes, Target Function Classes, and Network Computing Capacity

    E-Print Network [OSTI]

    Franceschetti, Massimo

    Linear Codes, Target Function Classes, and Network Computing Capacity Rathinakumar Appuswamy Submitted: May 6, 2011 Abstract We study the use of linear codes for network computing in single in network coding are applicable to network computing as well. Network computing problems arise in various

  16. Distributed Target Tracking with Directional Binary Sensor Networks

    E-Print Network [OSTI]

    Varela, Carlos

    a sector within the circular range around it. Examples of such sensors include cameras, infrared sensors on information gathered from all sensors to update the target's track. But particle filters are expensive to compute, and transmitting data from each node to a central one is very costly in terms of the energy

  17. ESS liquid-metal target design using computational fluid dynamics

    SciTech Connect (OSTI)

    Dury, T.V. [Paul Scherrer Institute, Villigen (Switzerland)

    1997-12-01T23:59:59.000Z

    The thermal-hydraulic performance of a spallation neutron source target limits the highest neutron fluxes that can be generated. The current design for the European spallation source consists of a liquid metal encased within a containing shell, wedge-shaped in the direction of the incoming proton beam, with rounded sides in a cross section through a plane normal to the beam.

  18. Cooling System for the MERIT High-Power Target Experiment

    E-Print Network [OSTI]

    McDonald, Kirk

    and a remote PVSS supervision station connected via Ethernet. Operation Modes: Cooling of proximity cryogenicsCooling System for the MERIT High-Power Target Experiment Haug F., Pereira H., Silva P., Pezzetti M a free mercury jet inside a normal conducting pulsed 15 T capture solenoid magnet cooled with liquid

  19. Chemical signatures and new drug targets for gametocytocidal drug

    E-Print Network [OSTI]

    Arnold, Jonathan

    Chemical signatures and new drug targets for gametocytocidal drug development Wei Sun1 *, Takeshi Q antimalarial drugs are not active against P. falciparum gametocytes, responsible for the spread of malaria screening 5,215 known drugs and compounds. All these compounds were active against three strains

  20. High-Power Density Target Design and Analyses for Accelerator

    E-Print Network [OSTI]

    McDonald, Kirk

    management ­ Lithium · Excellent conductivity, but low heat capacity compared to other coolants ­ Sodium · Better heat capacity than lithium ­ Mercury · Power generation in coolant limits applicability ­ Lithiumcooled Tungsten Plate Liquid Target Concepts ­ Lead Bismuth Eutectic Workshop on Applications of High

  1. Thin liquid lithium targets for high power density

    E-Print Network [OSTI]

    McDonald, Kirk

    High charge state High velocity flow ~60 m/s High heat capacity of Li Absorbs power depositedThin liquid lithium targets for high power density applications: heavy ion beam strippers and beta Hilton Malmö City #12;Outline Liquid Lithium Stripper idea for FRIB Brief theory of film stability

  2. Distribution, Morphology, and Synaptic Targets of Corticothalamic Terminals in

    E-Print Network [OSTI]

    Casanova, Christian

    Distribution, Morphology, and Synaptic Targets of Corticothalamic Terminals in the Cat Lateral terminals have been identified in higher order nuclei, large (type II) and smaller (type I), which have been into area 17 or PMLS. Results indicate that area 17 injections preferentially labelled large terminals

  3. COMPARING TARGET POSITION WITH PRESENT POSITION: NEURAL VECTORS

    E-Print Network [OSTI]

    Grossberg, Stephen

    in a head co- ordinate map. The calibration of intermodality movement signals, the attentional selection of a target position for an intentional movement, and the encoding of sequencesof predictive saccades can all then make use of the movement parameters that were learned in the visually reactive mode. We will argue

  4. Integrated nanoplasmonic-nanofluidic biosensors with targeted delivery of analytes

    E-Print Network [OSTI]

    Integrated nanoplasmonic-nanofluidic biosensors with targeted delivery of analytes Ahmet Ali Yanik the effective analyte transport. To overcome this limitation, we propose and demonstrate a nanoplasmonic-nanofluidic layers of microfluidic channels through plasmonic/nanofluidic holes. To implement the proposed sensor

  5. THERMAL LOADING OF A DIRECT DRIVE TARGET IN

    E-Print Network [OSTI]

    Raffray, A. René

    optics. A background gas, such as Xe, could reduce the damage on the wall from ion and heat loading fusion micro explosion (~ 10 Hz), ions and heat loads threaten to damage the reactor wall and driver. · The thermal loading of a target (radiation from the chamber wall and convection from the protective gas) may

  6. Sectoral targets for developing countries: Combining "Common but differentiated responsibilities"

    E-Print Network [OSTI]

    Paris-Sud XI, Universit de

    , as also is the impact on the electricity price. Keywords Sectoral approach, sectoral target, developing-type absolute commitments, whilst developing countries adopt an emission trading system limited to electricity are auctioned by the government, which distributes its revenues lump-sum to households. In a second scenario

  7. FEASIBILITY OF TARGET MATERIAL RECYCLING AS WASTE MANAGEMENT ALTERNATIVE

    E-Print Network [OSTI]

    California at San Diego, University of

    FEASIBILITY OF TARGET MATERIAL RECYCLING AS WASTE MANAGEMENT ALTERNATIVE L. EL-GUEBALY,* P. WILSON for Publication February 3, 2004 The issue of waste management has been studied simultaneously along with the development of the ARIES heavy-ion-driven inertial fusion energy (IFE) concept. Options for waste management

  8. Ion beam heated target simulations for warm dense matter physics and inertial fusion energy$

    E-Print Network [OSTI]

    Wurtele, Jonathan

    Ion beam heated target simulations for warm dense matter physics and inertial fusion energy$ J Keywords: Ion beam heating Warm dense matter Inertial fusion energy targets Hydrodynamic simulation a b fusion energy-related beam-target coupling. Simulations of various target materials (including solids

  9. Performance of a Clad Tungsten Rod Spallation Neutron Source Target

    SciTech Connect (OSTI)

    Sommer, Walter F. [Los Alamos National Laboratory (United States); Maloy, Stuart A. [Los Alamos National Laboratory (United States); Louthan, McIntyre R. [Savannah River National Laboratory (United States); Willcutt, Gordon J. [Los Alamos National Laboratory (United States); Ferguson, Phillip D. [Oak Ridge National Laboratory (United States); James, Michael R. [Los Alamos National Laboratory (United States)

    2005-09-15T23:59:59.000Z

    Tungsten rods, slip-clad with Type 304L stainless steel, performed successfully as a spallation neutron source target operating to a peak fluence of {approx}4 x 10{sup 21} p/cm{sup 2}. The target was used as a neutron source during the Accelerator Production of Tritium (APT) materials irradiation program at the Los Alamos Neutron Science Center. Tungsten rods of 2.642-mm diameter were slip-fit in Type 304L stainless steel tubes that had an inner diameter of 2.667 mm. The radial gap was filled with helium at atmospheric pressure and room temperature. Los Alamos High Energy Transport (LAHET) calculations suggest a time-averaged peak power deposition in the W of 2.25 kW/cm{sup 3}. Thermal-hydraulic calculations indicate that the peak centerline W temperature reached 271 deg. C. The LAHET calculations were also used to predict neutron and proton fluxes and spectra for the complex geometry used in the irradiation program. Activation foil sets distributed throughout the experiment were used to determine target neutronics performance as a comparison to the LAHET calculations. Examination of the irradiated target assemblies revealed no significant surface degradation or corrosion on either the Type 304L or the W surfaces. However, it was clear that the irradiation changed material properties because post-proton-irradiation measurements on Type 304L test samples from the APT program demonstrated increases in the yield strength and decreases in the ductility and fracture toughness with increasing dose, and the wrought W rod samples became brittle. Fortunately, the slip-clad target design subjects the materials to very low stress.

  10. An Assessment of Inertial Confinement Fusion Target Physics A Panel on Fusion Target Physics ("the Panel") will serve as a technical resource to the

    E-Print Network [OSTI]

    An Assessment of Inertial Confinement Fusion Target Physics A Panel on Fusion Target Physics ("the Panel") will serve as a technical resource to the Committee on Inertial Confinement Energy Systems ("the Physics will prepare a report that will assess the current performance of fusion targets associated

  11. KT McDonald Target Studies Meeting June 14, 2011 1 Mechanical Issues for the Target System

    E-Print Network [OSTI]

    McDonald, Kirk

    (+ cooling water). 4. Layout of the 6-T copper magnets (+ cooling water and electrical feeds). 5. Layout these items fit together? How can they be removed for repair? (Remote handling mandatory.) No lubricants. However, lubricants must be avoided in the high-radiation environment of the target system. The cooling

  12. Roll-up of validation results to a target application.

    SciTech Connect (OSTI)

    Hills, Richard Guy

    2013-09-01T23:59:59.000Z

    Suites of experiments are preformed over a validation hierarchy to test computational simulation models for complex applications. Experiments within the hierarchy can be performed at different conditions and configurations than those for an intended application, with each experiment testing only part of the physics relevant for the application. The purpose of the present work is to develop methodology to roll-up validation results to an application, and to assess the impact the validation hierarchy design has on the roll-up results. The roll-up is accomplished through the development of a meta-model that relates validation measurements throughout a hierarchy to the desired response quantities for the target application. The meta-model is developed using the computation simulation models for the experiments and the application. The meta-model approach is applied to a series of example transport problems that represent complete and incomplete coverage of the physics of the target application by the validation experiments.

  13. Longitudinal target-spin asymmetries for deeply virtual Compton scattering

    E-Print Network [OSTI]

    Seder, E; Pisano, S; Niccolai, S

    2014-01-01T23:59:59.000Z

    A measurement of the electroproduction of photons off protons in the deeply inelastic regime was performed at Jefferson Lab using a nearly 6-GeV electron beam, a longitudinally polarized proton target and the CEBAF Large Acceptance Spectrometer. Target-spin asymmetries for $ep\\to e'p'\\gamma$ events, which arise from the interference of the deeply virtual Compton scattering and the Bethe-Heitler processes, were extracted over the widest kinematics in $Q^2$, $x_B$, $t$ and $\\phi$, for 166 four-dimensional bins. In the framework of Generalized Parton Distributions (GPDs), at leading twist the $t$ dependence of these asymmetries provides insight on the spatial distribution of the axial charge of the proton, which appears to be concentrated in its center. These results also bring important and necessary constraints for the existing parametrizations of chiral-even GPDs.

  14. Longitudinal Target-Spin Asymmetries for Deeply Virtual Compton Scattering

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Seder, E.; Biselli, A; Pisano, S; Niccolai, S; Smith, G D.; Joo, K; Adhikari, K; Amaryan, M J.; Anderson, M D.; Anefalos Pereira, S; et al

    2015-01-01T23:59:59.000Z

    A measurement of the electroproduction of photons off protons in the deeply inelastic regime was performed at Jefferson Lab using a nearly 6-GeV electron beam, a longitudinally polarized proton target and the CEBAF Large Acceptance Spectrometer. Target-spin asymmetries for ep-->e'p'y events, which arise from the interference of the deeply virtual Compton scattering and the Bethe-Heitler processes, were extracted over the widest kinematics in Q2, xB, t and phi, for 166 four-dimensional bins. In the framework of Generalized Parton Distributions (GPDs), at leading twist the t dependence of these asymmetries provides insight on the spatial distribution of the axial charge ofmorethe proton, which appears to be concentrated in its center. These results also bring important and necessary constraints for the existing parametrizations of chiral-even GPDs.less

  15. Targeting nanodisks via a single chain variable antibody - Apolipoprotein chimera

    SciTech Connect (OSTI)

    Iovannisci, David M.; Beckstead, Jennifer A. [Children's Hospital Oakland Research Institute, 5700 Martin Luther King Jr. Way, Oakland, CA 94609 (United States); Ryan, Robert O. [Children's Hospital Oakland Research Institute, 5700 Martin Luther King Jr. Way, Oakland, CA 94609 (United States)], E-mail: rryan@chori.org

    2009-02-06T23:59:59.000Z

    Nanodisks (ND) are nanometer scale complexes of phospholipid and apolipoprotein that have been shown to function as drug delivery vehicles. ND harboring significant quantities of the antifungal agent, amphotericin B, or the bioactive isoprenoid, all trans retinoic acid, have been generated and characterized. As currently formulated, ND possess limited targeting capability. In this study, we constructed a single chain variable antibody (scFv).apolipoprotein chimera and assessed the ability of this fusion protein to form ND and recognize the antigen to which the scFv is directed. Data obtained revealed that {alpha}-vimentin scFv.apolipoprotein A-I is functional in ND formation and antigen recognition, opening the door to the use of such chimeras in targeting drug-enriched ND to specific tissues.

  16. Longitudinal target-spin asymmetries for deeply virtual Compton scattering

    E-Print Network [OSTI]

    E. Seder; A. Biselli; S. Pisano; S. Niccolai; the CLAS Collaboration

    2014-10-24T23:59:59.000Z

    A measurement of the electroproduction of photons off protons in the deeply inelastic regime was performed at Jefferson Lab using a nearly 6-GeV electron beam, a longitudinally polarized proton target and the CEBAF Large Acceptance Spectrometer. Target-spin asymmetries for $ep\\to e'p'\\gamma$ events, which arise from the interference of the deeply virtual Compton scattering and the Bethe-Heitler processes, were extracted over the widest kinematics in $Q^2$, $x_B$, $t$ and $\\phi$, for 166 four-dimensional bins. In the framework of Generalized Parton Distributions (GPDs), at leading twist the $t$ dependence of these asymmetries provides insight on the spatial distribution of the axial charge of the proton, which appears to be concentrated in its center. These results also bring important and necessary constraints for the existing parametrizations of chiral-even GPDs.

  17. Life Pure Fusion Target Designs: Status and Prospects

    SciTech Connect (OSTI)

    Amendt, P; Dunne, M; Ho, D; Lindl, J

    2011-10-20T23:59:59.000Z

    Analysis and radiation-hydrodynamics simulations for expected high-gain fusion target performance on a demonstration 1-GWe Laser Inertial Fusion Energy (LIFE) power plant are presented. The required laser energy driver is 2.2 MJ at a 0.351-{mu}m wavelength, and a fusion target gain greater than 60 at a repetition rate of 16 Hz is the design goal for economic and commercial attractiveness. A scaling-law analysis is developed to benchmark the design parameter space for hohlraum-driven central hot-spot ignition. A suite of integrated hohlraum simulations is presented to test the modeling assumptions and provide a basis for near-term experimental resolution of the key physics uncertainties on the National Ignition Facility.

  18. Design, Operations, and Safety Report for the MERIT Target System

    SciTech Connect (OSTI)

    Graves, Van B [ORNL; Spampinato, Philip Thomas [ORNL

    2007-09-01T23:59:59.000Z

    The Mercury Intense Target Project (MERIT) is a proof-of-principal experiment to determine the feasibility of using a free-jet of Hg as a spallation target in a Neutrino Factory or a Muon Collider facility. The 1-cm-diameter, 20-m/sec jet will be generated inside a 15-Tesla magnetic field, and high-speed optical diagnostics will be used to photograph the interaction between the Hg jet and a 24-GeV proton beam.The experiment is scheduled to be conducted at CERN in 2007. ORNL is responsible for the design, fabrication, and testing of a system to deliver the Hg jet within the confines of the 15-cm magnet bore. This report documents the functional and safety requirements of the Hg system along with descriptions of its interfaces to the other experimental equipment.

  19. Longitudinal Target-Spin Asymmetries for Deeply Virtual Compton Scattering

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Seder, E.; Biselli, A; Pisano, S; Niccolai, S; Smith, G D.; Joo, K; Adhikari, K; Amaryan, M J.; Anderson, M D.; Anefalos Pereira, S; Avakian, H; Battaglieri, M; Bedlinskiy, I; Bono, J; Boiarinov, S; Bosted, P; Briscoe, W; Brock, J; Brooks, W K.; Bueltmann, S; Burkert, V D.; Carman, D S.; Carlin, C; Celentano, A; Chandavar, S; Charles, G; Colaneri, L; Cole, P L.; Contalbrigo, M; Crabb, D; Crede, V; D'Angelo, A; Dashyan, N; De Vita, R; De Sanctis, E; Deur, A; Djalali, C; Doughty, D; Dupre, R; El Fassi, L; Elouadrhiri, L; Eugenio, P; Fedotov, G; Fegan, S; Filippi, A; Fleming, J A.; Fradi, A; Garillon, B; Garcon, M; Gevorgyan, N; Ghandilyan, Y; Giovanetti, K L.; Girod, F X.; Goetz, J T.; Gohn, W; Gothe, R W.; Griffioen, K A.; Guegan, B; Guidal, M; Guo, L; Hafidi, K; Hakobyan, H; Hanretty, C; Harrison, N; Hattawy, M; Hirlinger Saylor, N; Holtrop, M; Hughes, S M.; Ilieva, Y; Ireland, D G.; Ishkhanov, B S.; Isupov, E L.; Jo, H S.; Joosten, S; Keith, C D.; Keller, D; Khachatryan, G; Khandaker, M; Kim, A; Kim, W; Klein, A; Klein, F J.; Koirala, S; Kubarovsky, V; Kuhn, S E.; Lenisa, P; Livingston, K; Lu, H Y.; MacGregor, I J.D.; Markov, N; Mayer, M; McKinnon, B; Meekins, D G.; Mineeva, T; Mirazita, M; Mokeev, V; Montgomery, R; Moody, C I.; Moutarde, H; Movsisyan, A; Munoz Camacho, C; Nadel-Turonski, P; Niculescu, I; Osipenko, M; Ostrovidov, A I.; Paolone, M; Pappalardo, L L.; Park, K; Park, S; Pasyuk, E; Peng, P; Phelps, W; Pogorelko, O; Price, J W.; Prok, Y; Protopopescu, D; Puckett, A J.R.; Ripani, M; Rizzo, A; Rosner, G; Rossi, P; Roy, P; Sabatie, F; Salgado, C; Schott, D; Schumacher, R A.; Senderovich, I; Simonyan, A; Skorodumina, I; Sokhan, D; Sparveris, N; Stepanyan, S; Stoler, P; Strakovsky, I I.; Strauch, S; Sytnik, V; Taiuti, M; Tang, W; Tian, Y; Ungaro, M; Voskanyan, H; Voutier, E; Walford, N K.; Watts, D P.; Wei, X; Weinstein, L B.; Wood, M H.; Zachariou, N; Zana, L; Zhang, J; Zonta, I

    2015-01-01T23:59:59.000Z

    A measurement of the electroproduction of photons off protons in the deeply inelastic regime was performed at Jefferson Lab using a nearly 6-GeV electron beam, a longitudinally polarized proton target and the CEBAF Large Acceptance Spectrometer. Target-spin asymmetries for ep-->e'p'y events, which arise from the interference of the deeply virtual Compton scattering and the Bethe-Heitler processes, were extracted over the widest kinematics in Q2, xB, t and phi, for 166 four-dimensional bins. In the framework of Generalized Parton Distributions (GPDs), at leading twist the t dependence of these asymmetries provides insight on the spatial distribution of the axial charge of the proton, which appears to be concentrated in its center. These results also bring important and necessary constraints for the existing parametrizations of chiral-even GPDs.

  20. First polarization results from the LAMPF /sup 13/C target

    SciTech Connect (OSTI)

    Penttila, S.I.; Amann, J.F.; Jarmer, J.J.; Jones, K.W.; Tanaka, N.; Barlett, M.L.; Hoffmann, G.W.; Kielhorn, W.F.; Pauletta, G.; Purcell, M.

    1988-01-01T23:59:59.000Z

    A polarized /sup 13/C target has been developed and used to measure spin observables for 500-MeV p - /sup 13/C elastic scattering. The material was ethylene glycol, /sup 13/C/sub 2/H/sub 6/O/sub 2/, enriched to 99% in /sup 13/C. Both the /sup 13/C and /sup 1/H spins were dynamically polarized in a /sup 3/He refrigerator at 2.5-T magnetic field. The polarization of both species was measured by using the NMR thermal equilibrium calibration technique. In addition, the polarization of /sup 1/H was independently measured by p-p scattering. We described the target and reported on the polarizations obtained and the dependence of the polarizations on integrated beam intensity. 9 refs., 3 figs., 1 tab.

  1. Azimuthal asymmetries in SIDIS off unpolarized targets at COMPASS

    E-Print Network [OSTI]

    Andrea Bressan; for the COMPASS Collaboration

    2009-07-31T23:59:59.000Z

    Azimuthal asymmetries measured in unpolarized semi-inclusive deep inelastic scattering bring important information on the inner structure of the nucleons, and can be used both to estimate the average quark transverse momentum k_T and to access the so-far unmeasured Boer-Mulders functions. COMPASS results using part of the 2004 data collected with a 6LiD target and a 160 GeV positive muon beam are presented separately for positive and negative hadrons.

  2. Methods and compositions for targeting macromolecules into the nucleus

    DOE Patents [OSTI]

    Chook, Yuh Min

    2013-06-25T23:59:59.000Z

    The present invention includes compositions, methods and kits for directing an agent across the nuclear membrane of a cell. The present invention includes a Karyopherin beta2 translocation motif in a polypeptide having a slightly positively charged region or a slightly hydrophobic region and one or more R/K/H-X.sub.(2-5)-P-Y motifs. The polypeptide targets the agent into the cell nucleus.

  3. Target Value Design: Applications to Newborn Intensive Care Units

    E-Print Network [OSTI]

    Rybkowski, Zofia K.; Shepley, Mardelle McCuskey; Ballard, H. Glenn

    2015-02-08T23:59:59.000Z

    inducing flow, has been optimizing the three- legged stool of construction managementtime, cost, quality and safety (as the seat) (Jackson, 2004). Value is defined as what customers need to accomplish their purposes. Historically, TVD de- veloped... (Architecture); E (Engineering); CM (Construction Management) Table 1. A Comparison of Two Delivery Methods Note: OAEC stakeholders for the field house at St. Olaf engaged in target-costing exercises as a way to reduce cost and scheduleand enhance value...

  4. Magneto-Inertial Fusion (Magnetized Target Fusion)( g g )

    E-Print Network [OSTI]

    , 2011 U N C L A S S I F I E D Operated by the Los Alamos National Security, LLC for the DOE/NNSA Slide 1 for the DOE/NNSA Slide 2 Some MIF-IFE reactor considerations #12;A Wide Range of Driver/Target Combinations for the DOE/NNSA S. A. Slutz, et al., Phys. Plasmas 17, 056303 (2010) A. G. Lynn, et al, Rev. Sci. Instr. 81

  5. A Wide Temperature Range Cryostat for Polarised Target Material Preparation

    E-Print Network [OSTI]

    Dutz, Hartmut

    with current I and target density nt t 1 f 2 · P2 t · L · A2 t FOM = f 2 · P2 t · L is defining quality of frequency e + p DNP requirement: N Tn Te n Scott Reeve Wide Temperature · T Linear dependence of m on P laminar flow profile Falmer Scott Reeve Wide Temperature Range Cryostat 11

  6. Thin-thick hydrogen target for nuclear physics

    SciTech Connect (OSTI)

    Gheller, J.-M.; Juster, F.-P.; Authelet, G. [CEA Saclay, Irfu/SACM, F-91191 Gif-Sur-Yvette cedex (France); Vinyar, I. [PELIN Limited Liability Company 27 A, Gzhatskaya Str, office 103 St. Petersbourg 195220 (Russian Federation); Relland, J. [CEA Saclay, Irfu/SIS, F-91191 Gif-Sur-Yvette cedex (France); Commeaux, C. [Institut de Physique Nuclaire, campus Universitaire-Bat 103, 91406 Orsay cedex (France)

    2014-01-29T23:59:59.000Z

    In spectroscopic studies of unstable nuclei, hydrogen targets are of key importance. The CHyMENE Project aims to provide to the nuclear physics community a thin and pure solid windowless hydrogen or deuterium target. CHyMENE project must respond to this request for the production of solid Hydrogen. The solid hydrogen target is produced in a continuous flow (1 cm/s) by an extrusion technique (developed with the PELIN laboratory) in a vacuum chamber. The shape of the target is determined by the design of the nozzle at the extrusion process. For the purpose, the choice is a rectangular shape with a width of 10 mm and a thickness in the range of 30-50 microns necessary for the physics objectives. The cryostat is equipped with a GM Cryocooler with sufficient power for the solidification of the hydrogen in the lower portion of the extruder. In the higher part of the cryostat, the hydrogen gas is first liquefied and partially solidified. It is then compressed at 100 bars in the cooled extruder before expulsion of the film through the nozzle at the center of the reaction vacuum chamber. After the previous step, the solid hydrogen ribbon falls by gravity into a dedicated chamber where it sublimes and the gas is pumped and evacuated in a exhaust line. This paper deals with the design of the cryostat with its equipment, with the sizing of the thermal bridge (Aluminum and copper), with the results regarding the contact resistance as well as with the vacuum computations of the reaction and recovery hydrogen gas chambers.

  7. Time-resolved diagnostics for concrete target response

    SciTech Connect (OSTI)

    Baum, D.W.; Kuklo, R.M.; Reaugh, J.E.; Simonson, S.C.

    1996-05-01T23:59:59.000Z

    In order to facilitate the design of advanced penetrating weapons for defeating land targets, the interaction of concrete with high-velocity penetrators needs to be better characterized. To aid in this effort, three new types of time-resolved diagnostics are being developed and have been used in two experiments and one demonstration: fiber optic arrays to localize penetrators in space and time, Fabry-Perot velocimetry to record the concrete particle velocity, which is related to the pressure, at specific locations within concrete targets, and micropower impulse radar to provide a non-intrusive measure of the penetrator position-time history in a target. The two experiments used the fiber optic array and the Fabry-Perot velocimeter to diagnose the response of concrete to penetration by a Viper shaped charge jet. The results were analyzed using the CALE continuum mechanics simulation program, for which a preliminary model of the material properties of concrete was developed. The fiber optic arrays recorded the bow shock at locations 6.4 and 16.9 cm from the front surfaces. The Fabry-Perot velocimeter measured a free-surface velocity of 0.13 km/s at a distance of 3 cm and obliquity 70{degree} from the jet, which was moving at an interface velocity of 4.0 km/s at a depth of 29 cm. These values imply a pressure of about 6.6 kbar at that location. The demonstration used micropower impulse radar with a pulse repetition frequency of 0.25 MHz and a cell size of 30 ps to detect and record the motion of a metal penetrator simulant moving inside a cylindrical concrete target.

  8. Radioactive targets for nuclear astrophysics research at LANSCE

    SciTech Connect (OSTI)

    Koehler, P.E.; O'Brien, H.A.; Gursky, J.C.

    1990-01-01T23:59:59.000Z

    During the past few years we have made measurements of (n,p) and (n,{alpha}) cross sections on several radioactive nuclei of importance to nuclear astrophysics. The measurements were made at the Manuel Lujan, Jr., Neutron Scattering Center (LANSCE) from thermal neutron energy to approximately 100 keV. Successful measurements have been completed on the radioisotopes {sup 7}Be, {sup 22}Na and {sup 36}Cl while preliminary data have been taken on targets of {sup 54}Mn and {sup 55}Fe. Similar measurements have also been made on the stable isotopes {sup 14}N, {sup 17}O and {sup 35}Cl. We are currently assembling a 4{pi} barium fluoride (BaF{sub 2}) detector which will allow us to expand our program to (n,{gamma}) measurements. The (n,{gamma}) (and in some cases future (n,p)) measurements will require targets with higher specific activity and greater chemical purity than we have so far been able to use. We discuss the fabrication techniques used for the samples produced so far, the requirements the future (n,{gamma}) targets must meet and our current plans for producing them, and the physics motivations for the measurements.

  9. Laser remote sensing of backscattered light from a target sample

    DOE Patents [OSTI]

    Sweatt, William C. (Albuquerque, NM); Williams, John D. (Albuquerque, NM)

    2008-02-26T23:59:59.000Z

    A laser remote sensing apparatus comprises a laser to provide collimated excitation light at a wavelength; a sensing optic, comprising at least one optical element having a front receiving surface to focus the received excitation light onto a back surface comprising a target sample and wherein the target sample emits a return light signal that is recollimated by the front receiving surface; a telescope for collecting the recollimated return light signal from the sensing optic; and a detector for detecting and spectrally resolving the return light signal. The back surface further can comprise a substrate that absorbs the target sample from an environment. For example the substrate can be a SERS substrate comprising a roughened metal surface. The return light signal can be a surface-enhanced Raman signal or laser-induced fluorescence signal. For fluorescence applications, the return signal can be enhanced by about 10.sup.5, solely due to recollimation of the fluorescence return signal. For SERS applications, the return signal can be enhanced by 10.sup.9 or more, due both to recollimation and to structuring of the SERS substrate so that the incident laser and Raman scattered fields are in resonance with the surface plasmons of the SERS substrate.

  10. Target diagnostic system for the National Ignition Facility (NIF)

    SciTech Connect (OSTI)

    Leeper, R.J.; Chandler, G.A.; Cooper, G.W.; Derzon, M.S. [and others

    1996-07-01T23:59:59.000Z

    A review of recent progress on the design of a diagnostic system proposed for ignition target experiments on the National Ignition Facility (NIF) will be presented. This diagnostic package contains an extensive suite of optical, x-ray, gamma-ray, and neutron diagnostics that enable measurements of the performance of both direct and indirect driven NIF targets. The philosophy used in designing all of the diagnostics in the set has emphasized redundant and independent measurement of fundamental physical quantities relevant to the operation of the NIF target. A unique feature of these diagnostics is that they are being designed to be capable of operating, in the high radiation, EMP, and debris backgrounds expected on the NIF facility. The diagnostic system proposed can be categorized into three broad areas: laser characterization, hohlraum characterization, and capsule performance diagnostics. The operating principles of a representative instrument from each class of diagnostic employed in this package will be summarized and illustrated with data obtained in recent prototype diagnostic tests.

  11. The prospects for polarized target materials with pure carbon background

    SciTech Connect (OSTI)

    Hill, D.A.

    1992-10-06T23:59:59.000Z

    None of the materials presently in common use for polarized proton targets has a pure carbon nuclear background. The alcohols and diols contain some oxygen, and the ammonia and amine-based materials contain nitrogen and/or other noncarbon species. In the latter cases the noncarbon nuclei are measurably polarized as a concomitant of the process used to polarize the hydrogen nuclei. The relative simplicity of a pure carbon background would be advantageous for most types of scattering experiments and perhaps crucial for some. In addition to simplifying the kinematics of background events, pure carbon is relatively easy to prepare as a ``dummy`` target for background subtraction. Also, in such a target material, {sup 13}C-enrichment would yield a clean polarized {sup 13}C material. In this note I explore the possibilities for such materials, touching upon only what I consider to be the ``high`` points. The subject matter is capable of nearly endless ramification and speculation. In fact, owing to a general lack of relevant experimental data, even this relatively brief note contains much that is speculative to some degree.

  12. The prospects for polarized target materials with pure carbon background

    SciTech Connect (OSTI)

    Hill, D.A.

    1992-10-06T23:59:59.000Z

    None of the materials presently in common use for polarized proton targets has a pure carbon nuclear background. The alcohols and diols contain some oxygen, and the ammonia and amine-based materials contain nitrogen and/or other noncarbon species. In the latter cases the noncarbon nuclei are measurably polarized as a concomitant of the process used to polarize the hydrogen nuclei. The relative simplicity of a pure carbon background would be advantageous for most types of scattering experiments and perhaps crucial for some. In addition to simplifying the kinematics of background events, pure carbon is relatively easy to prepare as a dummy'' target for background subtraction. Also, in such a target material, [sup 13]C-enrichment would yield a clean polarized [sup 13]C material. In this note I explore the possibilities for such materials, touching upon only what I consider to be the high'' points. The subject matter is capable of nearly endless ramification and speculation. In fact, owing to a general lack of relevant experimental data, even this relatively brief note contains much that is speculative to some degree.

  13. Multimodality Imaging with Silica-Based Targeted Nanoparticle Platforms

    SciTech Connect (OSTI)

    Jason S. Lewis

    2012-04-09T23:59:59.000Z

    Objectives: To synthesize and characterize a C-Dot silica-based nanoparticle containing 'clickable' groups for the subsequent attachment of targeting moieties (e.g., peptides) and multiple contrast agents (e.g., radionuclides with high specific activity) [1,2]. These new constructs will be tested in suitable tumor models in vitro and in vivo to ensure maintenance of target-specificity and high specific activity. Methods: Cy5 dye molecules are cross-linked to a silica precursor which is reacted to form a dye-rich core particle. This core is then encapsulated in a layer of pure silica to create the core-shell C-Dot (Figure 1) [2]. A 'click' chemistry approach has been used to functionalize the silica shell with radionuclides conferring high contrast and specific activity (e.g. 64Cu and 89Zr) and peptides for tumor targeting (e.g. cRGD and octreotate) [3]. Based on the selective Diels-Alder reaction between tetrazine and norbornene, the reaction is bioorthogonal, highyielding, rapid, and water-compatible. This radiolabeling approach has already been employed successfully with both short peptides (e.g. octreotate) and antibodies (e.g. trastuzumab) as model systems for the ultimate labeling of the nanoparticles [1]. Results: PEGylated C-Dots with a Cy5 core and labeled with tetrazine have been synthesized (d = 55 nm, zeta potential = -3 mV) reliably and reproducibly and have been shown to be stable under physiological conditions for up to 1 month. Characterization of the nanoparticles revealed that the immobilized Cy5 dye within the C-Dots exhibited fluorescence intensities over twice that of the fluorophore alone. The nanoparticles were successfully radiolabeled with Cu-64. Efforts toward the conjugation of targeting peptides (e.g. cRGD) are underway. In vitro stability, specificity, and uptake studies as well as in vivo imaging and biodistribution investigations will be presented. Conclusions: C-Dot silica-based nanoparticles offer a robust, versatile, and multi-functional platform to enhance in vivo detection sensitivity and non-invasively assay receptor expression/status of tumor cellular targets, including those of low abundance, using nuclear-NIR fluorescence imaging approaches [2]. Improvements in molecular diagnostics, refined by the availability of nanotechnology platforms, will be a key determinant in driving early-stage disease detection and prevention, ultimately leading to decreases in mortality.

  14. Diamond Wire Saw for Precision Machining of Laser Target Components

    SciTech Connect (OSTI)

    Bono, M J; Bennett, D W

    2005-08-08T23:59:59.000Z

    The fabrication of precision laser targets requires a wide variety of specialized mesoscale manufacturing techniques. The diamond wire saw developed in this study provides the capability to precisely section meso-scale workpieces mounted on the assembly stations used by the Target Fabrication Group. This new capability greatly simplifies the fabrication of many types of targets and reduces the time and cost required to build the targets. A variety of materials are used to fabricate targets, including metals, plastics with custom designed chemical formulas, and aerogels of various densities. The materials are usually provided in the form of small pieces or cast rods that must be machined to the required shape. Many of these materials, such as metals and some plastics, can be trimmed using a parting tool on a diamond turning machine. However, other materials, such as aerogels and brittle materials, cannot be adequately cut with a parting tool. In addition, the geometry of the parts often requires that the workpieces be held in a special assembly station, which excludes the use of a parting tool. In the past, these materials were sectioned using a small, handheld coping saw that used a diamond-impregnated wire as a blade. This miniature coping saw was effective, but it required several hours to cut through certain materials. Furthermore, the saw was guided by hand and often caused significant damage to fragile aerogels. To solve these problems, the diamond wire saw shown in Figure 1 was developed. The diamond wire saw is designed to machine through materials that are mounted in the Target Fabrication Group's benchtop assembly stations. These assembly stations are the primary means of aligning and assembling target components, and there is often a need to machine materials while they are mounted in the assembly stations. Unfortunately, commercially available saws are designed for very different applications and are far too large to be used with the assembly stations. Therefore, a custom diamond wire saw was designed and constructed. The diamond wire saw cuts through workpieces using a continuous loop of diamond-impregnated wire of length 840 mm. The wire loop runs around several idler pulleys and is driven by a simple geared DC motor that rotates at 17 rpm. The linear speed of the wire is 107 inches/minute. The saw is oriented at an angle of 20{sup o} from horizontal, so the operator can view the wire through the cutout at the front end of the saw. When looking through a microscope or camera with a horizontal line of sight, the operator can clearly see the wire as it cuts through the workpiece, as shown in the right side of Figure 1. The saw is mounted on a two-axis stage that allows the operator to align the wire with the workpiece. To cut through the workpiece, the operator drives the wire through the workpiece by turning the feed micrometer. An image of the interior of the diamond wire saw appears in Figure 2. This picture was taken after removing the protective cover plate from the saw.

  15. Distillation of hydrogen isotopes for polarized HD target

    E-Print Network [OSTI]

    T. Ohta; S. Bouchigny; J. -P. Didelez; M. Fujiwara; K. Fukuda; H. Kohri; T. Kunimatsu; C. Morisaki; S. Ono; G. Rouill'; M. Tanaka; K. Ueda; M. Uraki; M. Utsuro; S. Y. Wang; M. Yosoi

    2011-12-12T23:59:59.000Z

    We have developed a cryogenic distillation system to purify Hydrogen-Deuteride (HD) gas for a polarized HD target in LEPS experiments at SPring-8. A small amount of ortho-H$_2$ ($\\sim$0.01%) in the HD gas plays an important role in efficiently polarizing the HD target. Since there are 1$\\sim$5% impurities of H$_2$ and D$_2$ in commercially available HD gases, it is inevitable that the HD gas is purified up to $\\sim$99.99%. The distillation system has a cryogenic pot (17$\\sim$21 K) containing many small stainless steel cells called Heli-pack. Commercial HD gas with an amount of 5.2 mol is fed into the pot. We carried out three distillation runs by changing temperatures (17.5 K and 20.5 K) and gas extraction speeds (1.3 ml/min and 5.2 ml/min). The extracted gas was analyzed by using a gas analyzer system combining a quadrupole mass spectrometer with a gas chromatograph. The HD gas of 1 mol with a purity better than 99.99% has been successfully obtained. The effective NTS (Number of Theoretical Stages), which is an indicator of the distillator performances, is obtained as 37.2$\\pm$0.6. This value is in reasonable agreement with a designed value of 37.9. The HD target is expected to be efficiently polarized under a well-controlled condition by doping an optimal amount of ortho-H$_2$ to the purified HD gas.

  16. Optical system for Argus 355-nm 90-mm aperture target-illumination experiments

    SciTech Connect (OSTI)

    Johnson, B.C.; Boyd, R.; Hermes, G.; Hildum, J.S.; Linford, G.; Martin, W.E.

    1982-02-01T23:59:59.000Z

    The requirements of laser alignment, crystal tuning, target alignment, and laser beam diagnosis are provided by this optical system. Initial setup and preshot alignment techniques are discussed. Layout and operation are contrasted with the 532 nm target experiments.

  17. TRANSPARENT CONDUCTING ZNO FILMS BY REACTIVE DC MAGNETRON SPUTTERING FROM METALLIC TARGETS

    E-Print Network [OSTI]

    Scofield, John H.

    , Oberlin College, Oberlin, OH 44074, USA 2 Ohio Aerospace Institute, Brookpark, OH 44142, USA 3 NASA Glenn pieces of Al over the Zn target, 2) sputtering from a Zn98Al02 alloy target, and 3) depostion

  18. Target-guided synthesis approach to the discovery of novel bivalent inhibitors of Glutathione Transferases

    E-Print Network [OSTI]

    Clipson, Alexandra Jayne

    2012-06-22T23:59:59.000Z

    Target-guided synthesis is an approach to drug discovery that uses the biological target as a template to direct synthesis of its own best inhibitors from small molecule fragments. The process bridges the gap between ...

  19. Target validation of a myokinin receptor from the southern cattle tick Boophilus microplus (Canestrini)

    E-Print Network [OSTI]

    Blandon, Maria Adylia

    2007-09-17T23:59:59.000Z

    suitable target for development of a novel acaricide, this target was validated by immunological disruption. A mixture of peptides, corresponding to the sequence of the extracellular loops of this receptor which were synthesized and linked to a carrier...

  20. Novel Ser/Thr Protein Phosphatase 5 (PP5) Regulated Targets during...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    SerThr Protein Phosphatase 5 (PP5) Regulated Targets during DNA Damage Identified by Proteomics Analysis. Novel SerThr Protein Phosphatase 5 (PP5) Regulated Targets during DNA...

  1. Measurement of the target current by inductive probe during laser interaction on terawatt laser system PALS

    SciTech Connect (OSTI)

    Cikhardt, J.; Klr, D.; ?ez?, K. [Czech Technical University in Prague, Faculty of Electrical Engineering, 166 27 Prague (Czech Republic); Institute of Plasma Physics AS CR, 182 00 Prague (Czech Republic); Krsa, J.; De Marco, M.; Pfeifer, M.; Velyhan, A.; Krousk, E. [Institute of Physics AS CR, 182 21 Prague (Czech Republic); Cikhardtov, B.; Kube, P.; Kravrik, J. [Czech Technical University in Prague, Faculty of Electrical Engineering, 166 27 Prague (Czech Republic); Ullschmied, J.; Skla, J. [Institute of Plasma Physics AS CR, 182 00 Prague (Czech Republic)

    2014-10-15T23:59:59.000Z

    Measurements of the return-current flowing through a solid target irradiated with the sub-nanosecond kJ-class Prague Asterix Laser System is reported. A new inductive target probe was developed which allows us measuring the target current derivative in a kA/ns range. The dependences of the target current on the laser pulse energy for cooper, graphite, and polyethylene targets are reported. The experiment shows that the target current is proportional to the deposited laser energy and is strongly affected by the shot-to-shot fluctuations. The corresponding maximum target charge exceeded a value of 10 ?C. A return-current dependence of the electromagnetic pulse produced by the laser-target interaction is presented.

  2. Radiation Damage of Polypropylene Fiber Targets in Storage Rings

    E-Print Network [OSTI]

    H. Rohdjess; D. Albers; J. Bisplinghoff; R. Bollmann; K. Buesser; O. Diehl; F. Dohrmann; H. -P. Engelhardt; P. D. Eversheim; J. Greiff; A. Gross; R. Gross-Hardt; F. Hinterberger; M. Igelbrink; R. Langkau; R. Maier; F. Mosel; M. Mueller; M. Muenstermann; D. Prasuhn; P. von Rossen; H. Scheid; N. Schirm; F. Schwandt; W. Scobel; H. J. Trelle; A. Wellinghausen; W. Wiedmann; K. Woller; R. Ziegler

    2004-03-23T23:59:59.000Z

    Thin polypropylene (CH$_2$) fibers have been used for internal experiments in storage rings as an option for hydrogen targets. The change of the hydrogen content due to the radiation dose applied by the circulating proton beam has been investigated in the range $1\\cdot10^6$ to $2\\cdot10^8$~Gy at beam momenta of 1.5 to 3 GeV/c by comparing the elastic pp-scattering yield to that from inelastic p-carbon reactions. It is found that the loss of hydrogen as a function of applied dose receives contributions from a fast and a slow component.

  3. Airborne Infrared Target Tracking with the Nintendo Wii Remote Sensor

    E-Print Network [OSTI]

    Beckett, Andrew 1984-

    2012-11-12T23:59:59.000Z

    AIRBORNE INFRARED TARGET TRACKING WITH THE NINTENDO WII REMOTE SENSOR A Thesis by ANDREW WILSON BECKETT Submitted to the O ce of Graduate Studies of Texas A&M University in partial ful llment of the requirements for the degree of MASTER... of UAS in use today and provide invaluable capabilities to both the military and civil services. UAS are well-suited to the ISR role: large UAS can remain airborne for far longer than the limits of human endurance without needing to be large enough...

  4. Topo II: An Enzyme Target for Antibacterial and Cancer Drugs

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What'sis Taking Over OurThe Iron Spin Transition in2, 2003Tool ofTopo II: An Enzyme Target for

  5. Topo II: An Enzyme Target for Antibacterial and Cancer Drugs

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What'sis Taking Over OurThe Iron Spin Transition in2, 2003Tool ofTopo II: An Enzyme Target forTopo II: An

  6. Heating and cooling gas-gun targets: nuts and bolts

    SciTech Connect (OSTI)

    Gustavsen, Richard L [Los Alamos National Laboratory; Bartram, Brian D [Los Alamos National Laboratory; Gehr, Russell J [HONEYWEL FM& T; Bucholtz, Scott M [HINEYWELL FM& T

    2009-01-01T23:59:59.000Z

    The nuts and bolts of a system used to heat and cool gas-gun targets is described. We have now used the system for more than 35 experiments, all of which have used electromagnetic gauging. Features of the system include a cover which is removed (remotely) just prior to projectile impact and the widespread use of metal/polymer insulations. Both the cover and insulation were required to obtain uniform temperatures in samples with low thermal conductivity. The use of inexpensive video cameras to make remote observations of the cover removal was found to be very useful. A brief catalog of useful glue, adhesive tape, insulation, and seal materials is given.

  7. DOE Program/Targets and Workshop Objectives | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't Your Destiny: Theof"WaveInteractions and Policy (2009) |Reservation |PlanProgram/Targets

  8. Combustion Targets for Low Emissions and High Efficiency | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't Your Destiny: Theof"Wave the White Flag"DepartmentToward Targets of EfficientModel

  9. Table IV: Technical Targets for Membranes: Stationary | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn'tOriginEducationVideoStrategic| Department of EnergyFOREnergy IV: Technical Targets for

  10. Targeted Microbial Development Presentation for BETO 2015 Project Peer Review

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn'tOriginEducationVideoStrategic| Department of EnergyFOREnergy IV:TankDepartmentTargeted

  11. FUEL & TARGET FABRICATION Aiken County, South Carolina

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Science (SC) Environmental Assessments (EA) /EmailMolecularGE,OzoneContacts& TARGET

  12. Designer Proteins Target Epstein-Barr-Virus-Associated Cancer

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville Power Administration wouldDECOMPOSITIONPortalToDepthand ImmobilizationDesigner Proteins Target

  13. Targets and measures for consideration of natural and cultural heritage assets in the transport system

    E-Print Network [OSTI]

    Nilsson, Lars; Sjlund, Anders

    2003-01-01T23:59:59.000Z

    and information. 5. Review and revision of quality targetsprojects 5. Training and Information 4. Revision of targets

  14. Independent Oversight Targeted Review, Y-12 National Security Complex- February 2012

    Broader source: Energy.gov [DOE]

    Targeted Review of Site Preparedness for Severe Natural Phenomena Events at the Y-12 National Security Complex

  15. DOE Targets for Onboard Hydrogen Storage Systems for Light-Duty...

    Broader source: Energy.gov (indexed) [DOE]

    FCT Program's Multiyear Research, Development and Demonstration Plan. targetsonboardhydrostorage.pdf More Documents & Publications Targets for Onboard Hydrogen Storage Systems...

  16. Target Tracking with Packet Delays and Losses QoI amid Latencies and Missing Data

    E-Print Network [OSTI]

    Massachusetts at Amherst, University of

    in the field, e.g., along the perimeter of a secured area, to monitor passing targets such as vehicles

  17. Controlling data transfers from an origin compute node to a target compute node

    DOE Patents [OSTI]

    Archer, Charles J. (Rochester, MN); Blocksome, Michael A. (Rochester, MN); Ratterman, Joseph D. (Rochester, MN); Smith, Brian E. (Rochester, MN)

    2011-06-21T23:59:59.000Z

    Methods, apparatus, and products are disclosed for controlling data transfers from an origin compute node to a target compute node that include: receiving, by an application messaging module on the target compute node, an indication of a data transfer from an origin compute node to the target compute node; and administering, by the application messaging module on the target compute node, the data transfer using one or more messaging primitives of a system messaging module in dependence upon the indication.

  18. The Neutrino Factory and Muon Collider Collaboration High-Power Targets and Particle Collection

    E-Print Network [OSTI]

    McDonald, Kirk

    Collaboration High-Power Targets Essential for Many Future Facilties ESS IFMIF ISOL/ Beams PSI APT ATW Kirk T

  19. Text-Alternative Version: Hitting the Target: ENERGY STAR SSL Outdoor Area Lighting

    Broader source: Energy.gov [DOE]

    Below is the text-alternative version of the Hitting the Target: ENERGY STAR SSL Outdoor Area Lighting Webcast.

  20. High Performance Computing and Storage Requirements for Biological and Environmental Research Target 2017

    E-Print Network [OSTI]

    Gerber, Richard

    2014-01-01T23:59:59.000Z

    Journal of High Performance Computing Applications Target 2017 High Performance Computing and Storage to characterize High Performance Computing (HPC)

  1. Channels of energy redistribution in short-pulse laser interactions with metal targets

    E-Print Network [OSTI]

    Zhigilei, Leonid V.

    Channels of energy redistribution in short-pulse laser interactions with metal targets Leonid V The kinetics and channels of laser energy redistribution in a target irradiated by a short, 1 ps, laser pulse of a target irradiated by a short laser pulse as well as on the characteristics of laser-induced phase

  2. NuMI Target Station AHIPA09 10/19/09

    E-Print Network [OSTI]

    McDonald, Kirk

    , remote connections · Materials survival experience, including target · Radiation safety surprise: tritium upgrading to 700 kW ~ 40% of energy ends up in target pile, ~ 1% stays in target as heat Components inside tactics. Pick: - increase spares so don't have to repair - invest in remote repair facilities - build

  3. ANALYSIS OF DATA FROM Z-PINCH MTF TARGET PLASMA EXPERIMENTS

    SciTech Connect (OSTI)

    F. WYSOCKI; J. TACCETTI; ET AL

    1999-04-01T23:59:59.000Z

    The Los Alamos National Laboratory Colt facility has been used to create target plasma for Magnetized Target Fusion (MTF). The primary results regarding magnetic field, plasma density, plasma temperature, and hot plasma lifetime are summarized and the suitability of these plasma targets for MTF is assessed.

  4. Gene-targeted microfluidic cultivation validated by isolation of a gut bacterium listed in Human

    E-Print Network [OSTI]

    Ismagilov, Rustem F.

    Gene-targeted microfluidic cultivation validated by isolation of a gut bacterium listed in Human, 2014) This paper describes a microfluidics-based workflow for geneti- cally targeted isolation that enables genetically targeted cultivation of microorganisms through a combination of microfluidics and on

  5. Carbon Target Initial Concept for 20to2T5m

    E-Print Network [OSTI]

    McDonald, Kirk

    Carbon Target Initial Concept for 20to2T5m (Updated) Van Graves January 30, 2014 #12;2 Managed by UT-Battelle for the U.S. Department of Energy Carbon Target Initial Concept 30 Jan 2014 Geometry From Ding's presentation Beam Dump for Carbon Target with IDS120h Configuration at 6.75 GeV (updated

  6. MRI-Visible Micellar Nanomedicine for Targeted Drug Delivery to Lung Cancer Cells

    E-Print Network [OSTI]

    Gao, Jinming

    MRI-Visible Micellar Nanomedicine for Targeted Drug Delivery to Lung Cancer Cells Jagadeesh Setti micelle (MFM) system that is encoded with a lung cancer-targeting peptide (LCP), and encapsulated. The LCP-encoded MFM showed significantly increased Rv 6-dependent cell targeting in H2009 lung cancer

  7. Rare target enrichment for ultrasensitive PCR detection using cotrehybridization and duplex-specific nuclease

    E-Print Network [OSTI]

    Fox, George

    Rare target enrichment for ultrasensitive PCR detection using cotrehybridization and duplexrehybridization Cot analysis Target enrichment Duplex-specific nuclease PCR sensitivity PCR diagnostics a b s t r a c to ultrasensitive PCR detection, using enrichment of rare target nucleic acid from abundant background by combining

  8. Infrared laser induced plasma diagnostics of silver target

    SciTech Connect (OSTI)

    Ahmat, L., E-mail: lubnaphysics@yahoo.com; Nadeem, Ali [Laser Spectroscopy Laboratory, National Institute of Lasers and Optronics (NILOP), P.O. Nilore, Islamabad 45650 (Pakistan); Ahmed, I. [Department of Physics and Applied Mathematics, Pakistan Institute of Engineering and Applied Sciences (PIEAS), P.O. Nilore, Islamabad 45650 (Pakistan)

    2014-09-15T23:59:59.000Z

    In the present work, the optical emission spectra of silver (Ag) plasma have been recorded and analyzed using the laser induced breakdown spectroscopy technique. The emission line intensities and plasma parameters were investigated as a function of lens to sample distance, laser irradiance, and distance from the target surface. The electron number density (n{sub e}) and electron temperature (T{sub e}) were determined using the Stark broadened line profile and Boltzmann plot method, respectively. A gradual increase in the spectral line intensities and the plasma parameters, n{sub e} from 2.89??10{sup 17} to 3.92??10{sup 17?}cm{sup ?3} and T{sub e} from 4662 to 8967?K, was observed as the laser irradiance was increased 2.29??10{sup 10}1.06??10{sup 11} W cm{sup ?2}. The spatial variations in n{sub e} and T{sub e} were investigated from 0 to 5.25?mm from the target surface, yielding the electron number density from 4.78??10{sup 17} to 1.72??10{sup 17?}cm{sup ?3} and electron temperature as 98693789?K. In addition, the emission intensities and the plasma parameters of silver were investigated by varying the ambient pressure from 0.36 to 1000 mbars.

  9. Diffusion-based DNA target colocalization by thermodynamic mechanisms

    E-Print Network [OSTI]

    Antonio Scialdone; Mario Nicodemi

    2011-05-04T23:59:59.000Z

    In eukaryotic cell nuclei, a variety of DNA interactions with nuclear elements occur, which, in combination with intra- and inter- chromosomal cross-talks, shape a functional 3D architecture. In some cases they are organized by active, i.e. actin/myosin, motors. More often, however, they have been related to passive diffusion mechanisms. Yet, the crucial questions on how DNA loci recognize their target and are reliably shuttled to their destination by Brownian diffusion are still open. Here, we complement the current experimental scenario by considering a physics model, in which the interaction between distant loci is mediated by diffusing bridging molecules. We show that, in such a system, the mechanism underlying target recognition and colocalization is a thermodynamic switch-like process (a phase transition) that only occurs if the concentration and affinity of binding molecules is above a threshold, or else stable contacts are not possible. We also briefly discuss the kinetics of this "passive-shuttling" process, as produced by random diffusion of DNA loci and their binders, and derive predictions based on the effects of genomic modifications and deletions.

  10. Development of portable NMR polarimeter system for polarized HD target

    E-Print Network [OSTI]

    Ohta, T; Didelez, J -P; Fujiwara, M; Fukuda, K; Kohri, H; Kunimatsu, T; Morisaki, C; Ono, S; Rouille, G; Tanaka, M; Ueda, K; Uraki, M; Utsuro, M; Wang, S Y; Yosoi, M

    2011-01-01T23:59:59.000Z

    A portable NMR polarimeter system has been developed to measure the polarization of a polarized Hydrogen-Deuteride (HD) target for hadron photoproduction experiments at SPring-8. The polarized HD target is produced at the Research Center for Nuclear Physics (RCNP), Osaka university and is transported to SPring-8. The HD polarization should be monitored at both places. We have constructed the portable NMR polarimeter system by replacing the devices in the conventional system with the software system with PCI eXtensions for Instrumentation (PXI). The weight of the NMR system is downsized from 80 kg to 7 kg, and the cost is reduced to 25%. We check the performance of the portable NMR polarimeter system. The signal-to-noise (S/N) ratio of the NMR signal for the portable system is about 50% of that for the conventional NMR system. This performance of the portable NMR system is proved to be compatible with the conventional NMR system for the polarization measurement.

  11. Distillation of hydrogen isotopes for polarized HD target

    E-Print Network [OSTI]

    Ohta, T; Didelez, J -P; Fujiwara, M; Fukuda, K; Kohri, H; Kunimatsu, T; Morisaki, C; Ono, S; Rouill', G; Tanaka, M; Ueda, K; Uraki, M; Utsuro, M; Wang, S Y; Yosoi, M

    2011-01-01T23:59:59.000Z

    We have developed a cryogenic distillation system to purify Hydrogen-Deuteride (HD) gas for a polarized HD target in LEPS experiments at SPring-8. A small amount of ortho-H$_2$ ($\\sim$0.01%) in the HD gas plays an important role in efficiently polarizing the HD target. Since there are 1$\\sim$5% impurities of H$_2$ and D$_2$ in commercially available HD gases, it is inevitable that the HD gas is purified up to $\\sim$99.99%. The distillation system has a cryogenic pot (17$\\sim$21 K) containing many small stainless steel cells called Heli-pack. Commercial HD gas with an amount of 5.2 mol is fed into the pot. We carried out three distillation runs by changing temperatures (17.5 K and 20.5 K) and gas extraction speeds (1.3 ml/min and 5.2 ml/min). The extracted gas was analyzed by using a gas analyzer system combining a quadrupole mass spectrometer with a gas chromatograph. The HD gas of 1 mol with a purity better than 99.99% has been successfully obtained. The effective NTS (Number of Theoretical Stages), which is...

  12. Development of portable NMR polarimeter system for polarized HD target

    E-Print Network [OSTI]

    T. Ohta; M. Fujiwara; K. Fukuda; H. Kohri; T. Kunimatsu; C. Morisaki; S. Ono; M. Tanaka; K. Ueda; M. Uraki; M. Utsuro; S. Y. Wang; M. Yosoi

    2011-03-09T23:59:59.000Z

    A portable NMR polarimeter system has been developed to measure the polarization of a polarized Hydrogen-Deuteride (HD) target for hadron photoproduction experiments at SPring-8. The polarized HD target is produced at the Research Center for Nuclear Physics (RCNP), Osaka university and is transported to SPring-8. The HD polarization should be monitored at both places. We have constructed the portable NMR polarimeter system by replacing the devices in the conventional system with the software system with PCI eXtensions for Instrumentation (PXI). The weight of the NMR system is downsized from 80 kg to 7 kg, and the cost is reduced to 25%. We check the performance of the portable NMR polarimeter system. The signal-to-noise (S/N) ratio of the NMR signal for the portable system is about 50% of that for the conventional NMR system. This performance of the portable NMR system is proved to be compatible with the conventional NMR system for the polarization measurement.

  13. Final work plan for targeted investigation at Hilton, Kansas.

    SciTech Connect (OSTI)

    LaFreniere, L. M.; Environmental Science Division

    2007-08-28T23:59:59.000Z

    This Work Plan outlines the scope of a targeted investigation to update the status of carbon tetrachloride contamination in groundwater associated with grain storage operations at Hilton, Kansas. The Commodity Credit Corporation (CCC), an agency of the U.S. Department of Agriculture (USDA), operated a grain storage facility in Hilton during the 1950s and 1960s. At the time of the CCC/USDA operation in Hilton, grain storage facilities (CCC/USDA and private) were located along the both sides of the former Union Pacific railroad tracks (Figure 1.1). The main grain storage structures were on or near the railroad right-of-way. The proposed targeted investigation, to be conducted by Argonne National Laboratory on the behalf of CCC/USDA, will supplement Argonne's Phase I and Phase II investigations in 1996-1997. The earlier investigations erroneously focused on an area east of the railroad property where the CCC/USDA did not operate, specifically on a private grain storage facility. In addition, the investigation was limited in scope, because access to railroad property was denied (Argonne 1997a,b). The hydrogeologic system at Hilton is potentially complex.

  14. Cylindrical target Li-beam-driven hohlraum experiments

    SciTech Connect (OSTI)

    Derzon, M.S.; Aubert, J.; Chandler, G.A. [and others

    1998-06-01T23:59:59.000Z

    The authors performed a series of experiments on the Particle Beam Fusion Accelerator II (PBFA II) in May, 1994, and obtained a brightness temperature of 61 {+-} 2 eV for an ion-beam heated hohlraum. The hohlraum was a 4-mm-diameter, right-circular cylinder with a 1.5-mm-thick gold wall, a low-density CH foam fill, and a 1.5- or 3-mm-diameter diagnostic aperture in the top. The nominal parameters of the radially-incident PBFA II Li ion beam were 9 MeV peak energy ({approximately}10 MeV at the gas cell) at the target at a peak power of 2.5 {+-} 0.3 TW/cm{sup 2} and a 15 ns pulse width. Azimuthal variations in intensity of a factor of 3, with respect to the mean, were observed. Nonuniformities in thermal x-ray emission across the area of the diagnostic hole were also observed. Time-dependent hole-closure velocities were measured: the time-averaged velocity of {approximately}2 cm/{micro}s is in good agreement with sound speed estimates. Unfolded x-ray spectra and brightness temperatures as a function of time are reported and compared to simulations. Hole closure corrections are discussed with comparisons between XRD and bolometer measurements. Temperature scaling with power on target is also presented.

  15. Visualization of Target Inspection data at the National Ignition Facility

    SciTech Connect (OSTI)

    Potter, D; Antipa, N

    2012-02-16T23:59:59.000Z

    As the National Ignition Facility continues its campaign to achieve ignition, new methods and tools will be required to measure the quality of the target capsules used to achieve this goal. Techniques have been developed to measure capsule surface features using a phase-shifting diffraction interferometer and Leica Microsystems confocal microscope. These instruments produce multi-gigabyte datasets which consist of tens to hundreds of files. Existing software can handle viewing a small subset of an entire dataset, but none can view a dataset in its entirety. Additionally, without an established mode of transport that keeps the target capsules properly aligned throughout the assembly process, a means of aligning the two dataset coordinate systems is needed. The goal of this project is to develop web based software utilizing WebGL which will provide high level overview visualization of an entire dataset, with the capability to retrieve finer details on demand, in addition to facilitating alignment of multiple datasets with one another based on common features that have been visually identified by users of the system.

  16. Separation of a target substance from a fluid or mixture using encapsulated sorbents

    DOE Patents [OSTI]

    Aines, Roger D; Spadaccini, Christopher M; Stolaroff, Joshuah K; Bourcier, William L; Lewis, Jennifer A; Duoss, Eric B; Vericella, John J

    2014-09-16T23:59:59.000Z

    Method and apparatus for separating a target substance from a fluid or mixture. Capsules having a coating and stripping solvents encapsulated in the capsules are provided. The coating is permeable to the target substance. The capsules having a coating and stripping solvents encapsulated in the capsules are exposed to the fluid or mixture. The target substance migrates through the coating and is taken up by the stripping solvents. The target substance is separated from the fluid or mixture by driving off the target substance from the capsules.

  17. Interaction-Dependent PCR: Identification of Ligand-Target Pairs from Libraries of Ligands and Libraries of Targets in a Single Solution-Phase

    E-Print Network [OSTI]

    Liu, David R.

    duplex. Extension links codes that identify the ligand and target into one selectively amplifiable DNA molecule. In a model selection, IDPCR resulted in the enrichment of DNA encoding all five known protein identification of ligands to this expanding number of targets is a major scientific and techno- logical challenge

  18. Target isolation system, high power laser and laser peening method and system using same

    DOE Patents [OSTI]

    Dane, C. Brent (Livermore, CA); Hackel, Lloyd A. (Livermore, CA); Harris, Fritz (Rocklin, CA)

    2007-11-06T23:59:59.000Z

    A system for applying a laser beam to work pieces, includes a laser system producing a high power output beam. Target delivery optics are arranged to deliver the output beam to a target work piece. A relay telescope having a telescope focal point is placed in the beam path between the laser system and the target delivery optics. The relay telescope relays an image between an image location near the output of the laser system and an image location near the target delivery optics. A baffle is placed at the telescope focal point between the target delivery optics and the laser system to block reflections from the target in the target delivery optics from returning to the laser system and causing damage.

  19. Target Allocation Methodology for China's Provinces: Energy Intensity in the 12th FIve-Year Plan

    SciTech Connect (OSTI)

    Ohshita, Stephanie; Price, Lynn

    2011-03-21T23:59:59.000Z

    Experience with China's 20% energy intensity improvement target during the 11th Five-Year Plan (FYP) (2006-2010) has shown the challenges of rapidly setting targets and implementing measures to meet them. For the 12th FYP (2011-2015), there is an urgent need for a more scientific methodology to allocate targets among the provinces and to track physical and economic indicators of energy and carbon saving progress. This report provides a sectoral methodology for allocating a national energy intensity target - expressed as percent change in energy per unit gross domestic product (GDP) - among China's provinces in the 12th FYP. Drawing on international experience - especially the European Union (EU) Triptych approach for allocating Kyoto carbon targets among EU member states - the methodology here makes important modifications to the EU approach to address an energy intensity rather than a CO{sub 2} emissions target, and for the wider variation in provincial energy and economic structure in China. The methodology combines top-down national target projections and bottom-up provincial and sectoral projections of energy and GDP to determine target allocation of energy intensity targets. Total primary energy consumption is separated into three end-use sectors - industrial, residential, and other energy. Sectoral indicators are used to differentiate the potential for energy saving among the provinces. This sectoral methodology is utilized to allocate provincial-level targets for a national target of 20% energy intensity improvement during the 12th FYP; the official target is determined by the National Development and Reform Commission. Energy and GDP projections used in the allocations were compared with other models, and several allocation scenarios were run to test sensitivity. The resulting allocations for the 12th FYP offer insight on past performance and offer somewhat different distributions of provincial targets compared to the 11th FYP. Recommendations for reporting and monitoring progress on the targets, and methodology improvements, are included.

  20. Streaked x-ray microscopy of laser-fusion targets

    SciTech Connect (OSTI)

    Price, R.H.; Campbell, E.M.; Rosen, M.D.; Auerbach, J.M.; Phillion, D.W.; Whitlock, R.R.; Obenshain, S.P.; McLean, E.A.; Ripin, B.H.

    1982-08-01T23:59:59.000Z

    An ultrafast soft x-ray streak camera has been coupled to a Wolter axisymmetric x-ray microscope. This system was used to observe the dynamics of laser fusion targets both in self emission and backlit by laser produced x-ray sources. Spatial resolution was 7 ..mu..m and temporal resolution was 20 ps. Data is presented showing the ablative acceleration of foils to velocities near 10/sup 7/ cm/sec and the collision of an accelerated foil with a second foil, observed using 3 keV streaked x-ray backlighting. Good agreement was found between hydrocode simulations, simple models of the ablative acceleration and the observed velocities of the carbon foils.

  1. APT {sup 3}He target/blanket. Topical report

    SciTech Connect (OSTI)

    NONE

    1995-03-01T23:59:59.000Z

    The {sup 3}He target/blanket (T/B) preconceptual design for the 3/8-Goal facility is based on a 1000-MeV, 200-mA accelerator to produce a high-intensity proton beam that is expanded and then strikes one of two T/B modules. Each module consists of a centralized neutron source made of tungsten and lead, a proton beam backstop region made of zirconium and lead, and a moderator made of D{sub 2}O. Helium-3 gas is circulated through the neutron source region and the blanket to create tritium through neutron capture. The gas is continually processed to extract the tritium with an online separation process.

  2. Cooling System for the Merit High-Power Target Experiment

    E-Print Network [OSTI]

    Haug, F; Silva, P; Pezzeti, M; Pavlov, O; Pirotte, O; Metselaar, J; Efthymiopoulos, I; Fabich, A; Lettry, J; Kirk, H G; McDonald, K T; Titus, P; Bennett, J R J; 10.1063/1.3422261

    2010-01-01T23:59:59.000Z

    MERIT is a proof-of-principle experiment of a target station suitable as source for future muon colliders or neutrino factories. When installed at the CERN (European Organization for Nuclear Research) PS (Proton Synchrotron)complex fast-extracted high-intensity proton beams intercepted a free mercury jet inside a normal-conducting, pulsed 15-T capture solenoid magnet cooled with liquid nitrogen. Up to 25 MJ of Joule heat was dissipated in the magnet during a pulse. The fully automated, remotely controlled cryogenic system of novel design permitted the transfer of nitrogen by the sole means of differential pressures inside the vessels. This fast cycling system permitted several hundred tests in less than three weeks during the 2007 data taking campaign.

  3. Preheat of radiative shock in double-shell ignition targets

    SciTech Connect (OSTI)

    Li, J. W.; He, X. T. [Key Lab of High Energy Density Physics Simulation, Center for Applied Physics and Technology, Peking University, Beijing 100871 (China) [Key Lab of High Energy Density Physics Simulation, Center for Applied Physics and Technology, Peking University, Beijing 100871 (China); Institute of Applied Physics and Computational Mathematics, P.O. Box 8009, Beijing 100094 (China); Pei, W. B.; Li, J. H.; Zheng, W. D.; Zhu, S. P. [Institute of Applied Physics and Computational Mathematics, P.O. Box 8009, Beijing 100094 (China)] [Institute of Applied Physics and Computational Mathematics, P.O. Box 8009, Beijing 100094 (China); Kang, W. [Key Lab of High Energy Density Physics Simulation, Center for Applied Physics and Technology, Peking University, Beijing 100871 (China)] [Key Lab of High Energy Density Physics Simulation, Center for Applied Physics and Technology, Peking University, Beijing 100871 (China)

    2013-08-15T23:59:59.000Z

    For the double-shell ignition target, the nonuniform preheat of the inner shell by high-energy x rays, especially the M-band line radiation and L-shell radiation from the Au hohlraum, aggravates the hydrodynamic instability that causes shell disruption. In this paper, for the first time, we propose another preheating mechanism due to the radiative shock formed in the CH foam, and also confirm and validate such preheat of radiative shock by numerical results. We also give an estimate of the improved double-shell in which the CH foam is replaced by the metallic foam to mitigate the hydrodynamic instabilities, and find that the radiative shock formed in the metallic foam produces a much stronger radiation field to preheat the inner shell, which plays a role in better controlling the instabilities. In double-shells, the preheat of radiative shock, as a potential effect on the instabilities, should be seriously realized and underlined.

  4. Shock-ignition relevant experiments with planar targets on OMEGA

    SciTech Connect (OSTI)

    Hohenberger, M.; Hu, S. X.; Anderson, K. S.; Boehly, T. R.; Sangster, T. C.; Seka, W.; Stoeckl, C.; Yaakobi, B. [Laboratory for Laser Energetics, University of Rochester, 250 East River Road, Rochester, New York 14623 (United States)] [Laboratory for Laser Energetics, University of Rochester, 250 East River Road, Rochester, New York 14623 (United States); Theobald, W.; Lafon, M.; Nora, R. [Laboratory for Laser Energetics, University of Rochester, 250 East River Road, Rochester, New York 14623 (United States) [Laboratory for Laser Energetics, University of Rochester, 250 East River Road, Rochester, New York 14623 (United States); Fusion Science Center, University of Rochester, Rochester, New York 14623 (United States); Betti, R.; Meyerhofer, D. D. [Laboratory for Laser Energetics, University of Rochester, 250 East River Road, Rochester, New York 14623 (United States) [Laboratory for Laser Energetics, University of Rochester, 250 East River Road, Rochester, New York 14623 (United States); Fusion Science Center, University of Rochester, Rochester, New York 14623 (United States); Departments of Mechanical Engineering and Physics, University of Rochester, Rochester, New York 14627 (United States); Casner, A. [CEA, DAM, DIF, Arpajon (France)] [CEA, DAM, DIF, Arpajon (France); Fratanduono, D. E. [Lawrence Livermore National Laboratory, P.O. Box 808, Livermore, California 94550 (United States)] [Lawrence Livermore National Laboratory, P.O. Box 808, Livermore, California 94550 (United States); Ribeyre, X.; Schurtz, G. [Centre Lasers Intenses et Applications, CELIA, Universit Bordeaux 1-CEA-CNRS, Talence (France)] [Centre Lasers Intenses et Applications, CELIA, Universit Bordeaux 1-CEA-CNRS, Talence (France)

    2014-02-15T23:59:59.000Z

    We report on laser-driven, strong-shock generation and hot-electron production in planar targets in the presence of a pre-plasma at shock-ignition (SI) relevant laser and pre-plasma conditions. 2-D simulations reproduce the shock dynamics well, indicating ablator shocks of up to 75 Mbar have been generated. We observe hot-electron temperatures of ?70?keV at intensities of 1.4??10{sup 15}?W/cm{sup 2} with multiple overlapping beams driving the two-plasmon decay instability. When extrapolated to SI-relevant intensities of ?10{sup 16}?W/cm{sup 2}, the hot electron temperature will likely exceed 100?keV, suggesting that tightly focused beams without overlap are better suited for launching the ignitor shock.

  5. Novel strategies for ultrahigh specific activity targeted nanoparticles

    SciTech Connect (OSTI)

    Zhou, Dong

    2012-12-13T23:59:59.000Z

    We have developed novel strategies optimized for preparing high specific activity radiolabeled nanoparticles, targeting nuclear imaging of low abundance biomarkers. Several compounds have been labeled with F-18 and Cu-64 for radiolabeling of SCK-nanoparticles via Copper(I) catalyzed or copper-free alkyne-azide cyclolization. Novel strategies have been developed to achieve ultrahigh specific activity with administrable amount of dose for human study using copper-free chemistry. Ligands for carbonic anhydrase 12 (CA12), a low abundance extracellular biomarker for the responsiveness of breast cancer to endocrine therapie, have been labeled with F-18 and Cu-64, and one of them has been evaluated in animal models. The results of this project will lead to major improvements in the use of nanoparticles in nuclear imaging and will significantly advance their potential for detecting low abundance biomarkers of medical importance.

  6. Structure-based receptor MIMICS targeted against bacterial superantigen toxins

    DOE Patents [OSTI]

    Gupta, Goutam (Santa Fe, NM); Hong-Geller, Elizabeth (Los Alamos, NM); Shiflett, Patrick R. (Los Alamos, NM); Lehnert, Nancy M. (Albuquerque, NM)

    2009-08-18T23:59:59.000Z

    The invention provides therapeutic compositions useful in the treatment of bacterial superantigen mediated conditions, such as Toxic Shock Syndrome. The compositions comprise genetically engineered bifunctional polypeptides containing a specific T-cell receptor binding domain and a specific MHC class II receptor binding domain, each targeting non-overlapping epitopes on a superantigen molecule against which they are designed. The anti-superantigen "receptor mimetics" or "chimeras" are rationally designed to recreate the modality of superantigen binding directly to both the TCR and the MHC-II receptor, and are capable of acting as decoys for superantigen binding, effectively out-competing the host T-cell and MHC-II receptors, the natural host receptors.

  7. Decommissioning and PIE of the MEGAPIE spallation target

    SciTech Connect (OSTI)

    Latge, C.; Henry, J. [CEA-Cadarache, DEN-DTN, 13108 Saint-Paul-les-Durance (France); Wohlmuther, M.; Dai, Y.; Gavillet, D.; Hammer, B.; Heinitz, S.; Neuhausen, J.; Schumann, D.; Thomsen, K.; Tuerler, A.; Wagner, W. [PSI, Villigen (Switzerland); Gessi, A. [ENEA, Brasimone (Italy); Guertin, A. [CNRS, Subatech, Nantes (France); Konstantinovic, M. [SCK-CEN, Mol (Belgium); Lindau, R. [KIT, Karlsruhe (Germany); Maloy, S. [DOE-LANL, Los Alamos (United States); Saito, S. [JAEA, Tokai (Japan)

    2013-07-01T23:59:59.000Z

    A key experiment in the Accelerated Driven Systems roadmap, the MEGAwatt PIlot Experiment (MEGAPIE) (1 MW) was initiated in 1999 in order to design and build a liquid lead-bismuth spallation target, then to operate it into the Swiss spallation neutron facility SINQ at Paul Scherrer Institute. The target has been designed, manufactured, and tested during integral tests, before irradiation carried out end of 2006. During irradiation, neutron and thermo hydraulic measurements were performed allowing deep interpretation of the experiment and validation of the models used during design phase. The decommissioning, Post Irradiation Examinations and waste management phases were defined properly. The phases dedicated to cutting, sampling, cleaning, waste management, samples preparation and shipping to various laboratories were performed by PSI teams: all these phases constitute a huge work, which allows now to perform post-irradiation examination (PIE) of structural material, irradiated in relevant conditions. Preliminary results are presented in the paper, they concern chemical characterization. The following radio-nuclides have been identified by ?-spectrometry: {sup 60}Co, {sup 101}Rh, {sup 102}Rh, {sup 108m}Ag, {sup 110m}Ag, {sup 133}Ba, {sup 172}Hf/Lu, {sup 173}Lu, {sup 194}Hg/Au, {sup 195}Au, {sup 207}Bi. For some of these nuclides the activities can be easily evaluated from ?-spectrometry results ({sup 207}Bi, {sup 194}Hg/Au), while other nuclides can only be determined after chemical separations ({sup 108m}Ag, {sup 110m}Ag, {sup 195}Au, {sup 129}I, {sup 36}Cl and ?-emitting {sup 208-210}Po). The concentration of {sup 129}I is lower than expected. The chemical analysis already performed on spallation and corrosion products in the lead-bismuth eutectic (LBE) are very relevant for further applications of LBE as a spallation media and more generally as a coolant.

  8. Binary electrokinetic separation of target DNA from background DNA primers.

    SciTech Connect (OSTI)

    James, Conrad D.; Derzon, Mark Steven

    2005-10-01T23:59:59.000Z

    This report contains the summary of LDRD project 91312, titled ''Binary Electrokinetic Separation of Target DNA from Background DNA Primers''. This work is the first product of a collaboration with Columbia University and the Northeast BioDefense Center of Excellence. In conjunction with Ian Lipkin's lab, we are developing a technique to reduce false positive events, due to the detection of unhybridized reporter molecules, in a sensitive and multiplexed detection scheme for nucleic acids developed by the Lipkin lab. This is the most significant problem in the operation of their capability. As they are developing the tools for rapidly detecting the entire panel of hemorrhagic fevers this technology will immediately serve an important national need. The goal of this work was to attempt to separate nucleic acid from a preprocessed sample. We demonstrated the preconcentration of kilobase-pair length double-stranded DNA targets, and observed little preconcentration of 60 base-pair length single-stranded DNA probes. These objectives were accomplished in microdevice formats that are compatible with larger detection systems for sample pre-processing. Combined with Columbia's expertise, this technology would enable a unique, fast, and potentially compact method for detecting/identifying genetically-modified organisms and multiplexed rapid nucleic acid identification. Another competing approach is the DARPA funded IRIS Pharmaceutical TIGER platform which requires many hours for operation, and an 800k$ piece of equipment that fills a room. The Columbia/SNL system could provide a result in 30 minutes, at the cost of a few thousand dollars for the platform, and would be the size of a shoebox or smaller.

  9. New Target Methodology: Polymer-Assisted Deposition and Its Applications on Gas-Phase Nuclear Chemistry with Rutherfordium

    E-Print Network [OSTI]

    Garcia, Mitch Andre

    2009-01-01T23:59:59.000Z

    on the thicknesses of the uranium tetrafluoride targets andcarbon, aluminum, and uranium tetrafluoride were calculatednine arc-shaped uranium(IV) tetrafluoride targets. The wheel

  10. HERMES Measurement of DVCS from p and d Targets, and Status and Prospects of the Recoil Detector

    E-Print Network [OSTI]

    ), longitudinal target-spin (LTSA) and the transverse target-spin (TTSA) asymmetries are d(e+ , p) - d(e- , p

  11. Polarimetry of the polarized hydrogen deuteride HDice target under an electron beam

    SciTech Connect (OSTI)

    Laine, Vivien E. [Universite Blaise Pascal

    2013-10-01T23:59:59.000Z

    The study of the nucleon structure has been a major research focus in fundamental physics in the past decades and still is the main research line of the Thomas Jefferson National Accelerator Facility (Jefferson Lab). For this purpose and to obtain statistically meaningful results, having both a polarized beam and a highly efficient polarized target is essential. For the target, this means high polarization and high relative density of polarized material. A Hydrogen Deuteride (HD) target that presents both such characteristics has been developed first at Brookhaven National Lab (BNL) and brought to the Hall B of Jefferson Lab in 2008. The HD target has been shown to work successfully under a high intensity photon beam (BNL and Jefferson Lab). However, it remained to be seen if the target could stand an electron beam of reasonably high current (nA). In this perspective, the target was tested for the first time in its frozen spin mode under an electron beam at Jefferson Lab in 2012 during the g14 experiment. This dissertation presents the principles and usage procedures of this HD target. The polarimetry of this target with Nuclear Magnetic Resonance (NMR) during the electron beam tests is also discussed. In addition, this dissertation also describes another way to perform target polarimetry with the elastic scattering of electrons off a polarized target by using data taken on helium-3 during the E97-110 experiment that occurred in Jefferson Lab's Hall A in 2003.

  12. National Ignition Facility Cryogenic Target Systems Interim Management Plan

    SciTech Connect (OSTI)

    Warner, B

    2002-04-25T23:59:59.000Z

    Restricted availability of funding has had an adverse impact, unforeseen at the time of the original decision to projectize the National Ignition Facility (NIF) Cryogenic Target Handling Systems (NCTS) Program, on the planning and initiation of these efforts. The purpose of this document is to provide an interim project management plan describing the organizational structure and management processes currently in place for NCTS. Preparation of a Program Execution Plan (PEP) for NCTS has been initiated, and a current draft is provided as Attachment 1 to this document. The National Ignition Facility is a multi-megajoule laser facility being constructed at Lawrence Livermore National Laboratory (LLNL) by the National Nuclear Security Administration (NNSA) in the Department of Energy (DOE). Its primary mission is to support the Stockpile Stewardship Program (SSP) by performing experiments studying weapons physics, including fusion ignition. NIF also supports the missions of weapons effects, inertial fusion energy, and basic science in high-energy-density physics. NIF will be operated by LLNL under contract to the University of California (UC) as a national user facility. NIF is a low-hazard, radiological facility, and its operation will meet all applicable federal, state, and local Environmental Safety & Health (ES&H) requirements. The NCTS Interim Management Plan provides a summary of primary design criteria and functional requirements, current organizational structure, tracking and reporting procedures, and current planning estimates of project scope, cost, and schedule. The NIF Director controls the NIF Cryogenic Target Systems Interim Management Plan. Overall scope content and execution schedules for the High Energy Density Physics Campaign (SSP Campaign 10) are currently undergoing rebaselining and will be brought into alignment with resources expected to be available throughout the NNSA Future Years National Security Plan (FYNSP). The revised schedule for delivering this system will be decided at the national level, based on experiment campaign requirement dates that will be derived through this process. The current milestone date for achieving indirect-drive ignition on the NIF is December 2010. Maintaining this milestone requires that the cryogenic systems be complete and available for fielding experiments early enough that the planned experimental campaigns leading up to ignition can be carried out. The capability of performing non-ignition cryogenic experiments is currently required by March 2006, when the NIF's first cluster of beams is operational. Plans for cryogenic and non-cryogenic experiments on the NIF are contained in NNSA's Campaign 10 Program Plans for Ignition (MTE 10.1) and High Energy Density Sciences (MTE 10.2). As described in this document, the NCTS Program Manager is responsible for managing NIF Cryogenic Target Systems development, engineering, and deployment. Through the NIF Director, the NCTS Program Manager will put in place an appropriate Program Execution Plan (draft attached) at a later time consistent with the maturing and funding these efforts. The PEP will describe management methods for carrying out these activities.

  13. Measurement of azimuthal asymmetries associated with deeply virtual Compton scattering on a longitudinally polarized deuterium target

    E-Print Network [OSTI]

    Airapetian, A; Akopov, Z; Aschenauer, E C; Augustyniak, W; Avakian, R; Avetissian, A; Avetisyan, E; Belostotski, S; Bianchi, N; Blok, H P; Borissov, A; Bowles, J; Brodski, I; Bryzgalov, V; Burns, J; Capiluppi, M; Capitani, G P; Cisbani, E; Ciullo, G; Contalbrigo, M; Dalpiaz, P F; Deconinck, W; De Leo, R; De Nardo, L; De Sanctis, E; Diefenthaler, M; Di Nezza, P; Dueren, M; Ehrenfried, M; Elbakian, G; Ellinghaus, F; Fantoni, A; Felawka, L; Frullani, S; Gabbert, D; Gapienko, G; Gapienko, V; Garibaldi, F; Gavrilov, G; Gharibyan, V; Giordano, F; Gliske, S; Golembiovskaya, M; Hadjidakis, C; Hartig, M; Hasch, D; Hill, G; Hillenbrand, A; Hoek, M; Holler, Y; Hristova, I; Imazu, Y; Ivanilov, A; Jackson, H E; Jgoun, A; Jo, H S; Joosten, S; Kaiser, R; Karyan, G; Keri, T; Kinney, E; Kisselev, A; Kobayashi, N; Korotkov, V; Kozlov, V; Krauss, B; Kravchenko, P; Krivokhijine, V G; Lagamba, L; Lamb, R; Lapikas, L; Lehmann, I; Lenisa, P; Linden-Levy, L A; Ruiz, A Lopez; Lorenzon, W; Lu, X -G; Lu, X -R; Ma, B -Q; Mahon, D; Makins, N C R; Manaenkov, S I; Manfre, L; Mao, Y; Marianski, B; de la Ossa, A Martinez; Marukyan, H; Miller, C A; Movsisyan, A; Muccifora, V; Murray, M; Mueller, D; Mussgiller, A; Nappi, E; Naryshkin, Y; Nass, A; Negodaev, M; Nowak, W -D; Pappalardo, L L; Perez-Benito, R; Pickert, N; Raithel, M; Reimer, P E; Reolon, A R; Riedl, C; Rith, K; Rosner, G; Rostomyan, A; Rubin, J; Ryckbosch, D; Salomatin, Y; Sanftl, F; Schaefer, A; Schnell, G; Schueler, K P; Seitz, B; Shibata, T -A; Shutov, V; Stancari, M; Statera, M; Steffens, E; Steijger, J J M; Stenzel, H; Stewart, J; Stinzing, F; Taroian, S; Terkulov, A; Trzcinski, A; Tytgat, M; Vandenbroucke, A; Van der Nat, P B; Van Haarlem, Y; Van Hulse, C; Veretennikov, D; Vikhrov, V; Vilardi, I; Vogel, C; Wang, S; Yaschenko, S; Ye, Z; Yen, S; Yu, W; Zeiler, D; Zihlmann, B; Zupranski, P

    2010-01-01T23:59:59.000Z

    Azimuthal asymmetries in exclusive electroproduction of a real photon from a longitudinally polarized deuterium target are measured with respect to target polarization alone and with respect to target polarization combined with beam helicity and/or beam charge. The asymmetries appear in the distribution of the real photons in the azimuthal angle $\\phi$ around the virtual photon direction, relative to the lepton scattering plane. The asymmetries arise from the deeply virtual Compton scattering process and its interference with the Bethe-Heitler process. The results for the beam-charge and beam-helicity asymmetries from a tensor polarized deuterium target with vanishing vector polarization are shown to be compatible with those from an unpolarized deuterium target, which is expected for incoherent scattering dominant at larger momentum transfer. Furthermore, the results for the single target-spin asymmetry and for the double-spin asymmetry are found to be compatible with the corresponding asymmetries previously ...

  14. Compression and combustion of non-cryogenic targets with a solid thermonuclear fuel for inertial fusion

    SciTech Connect (OSTI)

    Gus'kov, S. Yu., E-mail: guskov@sci.lebedev.ru [Russian Academy of Sciences, Lebedev Physical Institute (Russian Federation); Zmitrenko, N. V. [Russian Academy of Sciences, Keldysh Institute of Applied Mathematics (Russian Federation); Sherman, V. E. [St. Petersburg State Polytechnic University (Russian Federation)

    2013-04-15T23:59:59.000Z

    Variants of a target with a solid thermonuclear fuel in the form of deuterium-tritium hydrides of light metals for an inertial fusion have been proposed. The laser-pulse-induced compression of non-cryogenic targets, as well as ignition and combustion of such targets, has been examined. The numerical calculations show that, despite a decrease in the caloric content of the fuel and an increase in the energy losses on intrinsic radiation in the target containing deuterium-tritium hydrides of light metals as compared to the target containing deuterium-tritium ice, the non-cryogenic target can ensure the fusion gain sufficient for its use in the energy cycle of a thermonuclear power plant based on the inertial plasma confinement method.

  15. Nuclear Targets for a Precision Measurement of the Neutral Pion Radiative Width

    E-Print Network [OSTI]

    P. Martel; E. Clinton; R. McWilliams; D. Lawrence; R. Miskimen; A. Ahmidouch; P. Ambrozewicz; A. Asratyan; K. Baker; L. Benton; A. Bernstein; P. Cole; P. Collins; D. Dale; S. Danagoulian; G. Davidenko; R. Demirchyan; A. Deur; A. Dolgolenko; G. Dzyubenko; A. Evdokimov; J. Feng; M. Gabrielyan; L. Gan; A. Gasparian; O. Glamazdin; V. Goryachev; V. Gyurjyan; K. Hardy; M. Ito; M. Khandaker; P. Kingsberry; A. Kolarkar; M. Konchatnyi; O. Korchin; W. Korsch; S. Kowalski; M. Kubantsev; V. Kubarovsky; I. Larin; V. Matveev; D. McNulty; B. Milbrath; R. Minehart; V. Mochalov; S. Mtingwa; I. Nakagawa; S. Overby; E. Pasyuk; M. Payen; R. Pedroni; Y. Prok; B. Ritchie; C. Salgado; A. Sitnikov; D. Sober; W. Stephens; A. Teymurazyan; J. Underwood; A. Vasiliev; V. Verebryusov; V. Vishnyakov; M. Wood

    2008-11-13T23:59:59.000Z

    A technique is presented for precision measurements of the area densities, density * T, of approximately 5% radiation length carbon and 208Pb targets used in an experiment at Jefferson Laboratory to measure the neutral pion radiative width. The precision obtained in the area density for the carbon target is +/- 0.050%, and that obtained for the lead target through an x-ray attenuation technique is +/- 0.43%.

  16. Impact of cost constraints on aesthetic ranking following Target Value Design exercises

    E-Print Network [OSTI]

    Rybkowski, Zofia K.; Munankami, Manish; Gottipati, Udaya; Lavy, Sarel; Fernndez-Solis, Jose

    2011-07-13T23:59:59.000Z

    IMPACT OF COST CONSTRAINTS ON AESTHETIC RANKING FOLLOWING TARGET VALUE DESIGN EXERCISES Zofia K. Rybkowski1, Manish Munankami2, Udaya Gottipati3, Jose Fernndez-Sols 4, and Sarel Lavy5 PURPOSE: Target Value Design (TVD) is a project... delivery subset that shares methodologies with Target Costing and Value Engineering, but is performed within the context of lean construction. TVD has been shown to generate first cost savings of approximately 20% on case study projects. A concern voiced...

  17. Final work plan for targeted sampling at Webber, Kansas.

    SciTech Connect (OSTI)

    LaFreniere, L. M.; Environmental Science Division

    2006-05-01T23:59:59.000Z

    This Work Plan outlines the scope of work for targeted sampling at Webber, Kansas (Figure 1.1). This activity is being conducted at the request of the Kansas Department of Health and Environment (KDHE), in accordance with Section V of the Intergovernmental Agreement between the KDHE and the Commodity Credit Corporation of the U.S. Department of Agriculture (CCC/USDA). Data obtained in this sampling event will be used to (1) evaluate the current status of previously detected contamination at Webber and (2) determine whether the site requires further action. This work is being performed on behalf of the CCC/USDA by the Environmental Science Division of Argonne National Laboratory. Argonne is a nonprofit, multidisciplinary research center operated by the University of Chicago for the U.S. Department of Energy (DOE). The CCC/USDA has entered into an interagency agreement with DOE, under which Argonne provides technical assistance to the CCC/USDA with environmental site characterization and remediation at its former grain storage facilities. Argonne has issued a Master Work Plan (Argonne 2002) that describes the general scope of and guidance for all investigations at former CCC/USDA facilities in Kansas. The Master Work Plan, approved by the KDHE, contains the materials common to investigations at all locations in Kansas. This document should be consulted for complete details of the technical activities proposed at the former CCC/USDA facility in Webber.

  18. Alveolar targeting of aerosol pentamidine. Toward a rational delivery system

    SciTech Connect (OSTI)

    Simonds, A.K.; Newman, S.P.; Johnson, M.A.; Talaee, N.; Lee, C.A.; Clarke, S.W. (Royal Free Hospital, London (England))

    1990-04-01T23:59:59.000Z

    Nebulizer systems that deposit a high proportion of aerosolized pentamidine on large airways are likely to be associated with marked adverse side effects, which may lead to premature cessation of treatment. We have measured alveolar deposition and large airway-related side effects (e.g., cough, breathlessness, and effect on pulmonary function) after aerosolization of 150 mg pentamidine isethionate labeled with {sup 99m}Tc-Sn-colloid. Nine patients with AIDS were studied using three nebulizer systems producing different droplet size profiles: the Acorn System 22, Respirgard II, and Respirgard II with the inspiratory baffle removed. Alveolar deposition was greatest and side effects least with the nebulizer producing the smallest droplet size profile (Respirgard II), whereas large airway-related side effects were prominent and alveolar deposition lowest with the nebulizer producing the largest droplet size (Acorn System 22). Values for alveolar deposition and adverse airway effects were intermediate using the Respirgard with inspiratory baffle removed, thus indicating the importance of the baffle valve in determining droplet size. Addition of a similar baffle valve to the Acorn System 22 produced a marked improvement in droplet size profile. Selection of a nebulizer that produces an optimal droplet size range offers the advantage of enhancing alveolar targeting of aerosolized pentamidine while reducing large airway-related side effects.

  19. Study of hadron interactions in a lead-emulsion target

    E-Print Network [OSTI]

    Hirokazu Ishida; Tsutomu Fukuda; Takafumi Kajiwara; Koichi Kodama; Masahiro Komatsu; Tomokazu Matsuo; Shoji Mikado; Mitsuhiro Nakamura; Satoru Ogawa; Andrey Sheshukov; Hiroshi Shibuya; Jun Sudou; Taira Suzuki; Yusuke Tsuchida

    2014-08-02T23:59:59.000Z

    Topological and kinematical characteristics of hadron interactions have been studied using a lead-emulsion target exposed to 2, 4 and 10 GeV/c hadron beams. A total length of 60 m $\\pi^-$ tracks was followed using a high speed automated emulsion scanning system. A total of 318 hadron interaction vertices and their secondary charged particle tracks were reconstructed. Measurement results of interaction lengths, charged particle multiplicity, emission angles and momenta of secondary charged particles are compared with a Monte Carlo simulation and appear to be consistent. Nuclear fragments emitted from interaction vertices were also detected by a newly developed emulsion scanning system with wide-angle acceptance. Their emission angle distributions are in good agreement with the simulated distributions. Probabilities of an event being associated with at least one fragment track are found to be greater than 50% for beam momentum $P > 4$ GeV/c and are well reproduced by the simulation. These experimental results validate estimation of the background due to hadron interactions in the sample of $\\tau$ decay candidates in the OPERA $\

  20. Relativistic high harmonic generation in gas jet targets

    SciTech Connect (OSTI)

    Pirozhkov, A.S.; Kando, M.; Esirkepov, T.Zh.; and others

    2012-07-11T23:59:59.000Z

    We experimentally demonstrate a new regime of high-order harmonic generation by relativistic-irradiance lasers in gas jet targets. Bright harmonics with both odd and even orders, generated by linearly as well as circularly polarized pulses, are emitted in the forward direction, while the base harmonic frequency is downshifted. A 9 TW laser generates harmonics up to 360 eV, within the 'water window' spectral region. With a 120 TW laser producing 40 uJ/sr per harmonic at 120 eV, we demonstrate the photon number scalability. The observed harmonics cannot be explained by previously suggested scenarios. A novel high-order harmonics generation mechanism [T. Zh. Esirkepov et al., AIP Proceedings, this volume], which explains our experimental findings, is based on the phenomena inherent in the relativistic laser - underdense plasma interactions (self-focusing, cavity evacuation, and bow wave generation), mathematical catastrophe theory which explains formation of electron density singularities (cusps), and collective radiation due to nonlinear oscillations of a compact charge.

  1. In celebration of the fixed target program with the Tevatron

    SciTech Connect (OSTI)

    Jeffrey A. Appel et al.

    2001-12-28T23:59:59.000Z

    The Tevatron is the world's first large superconducting accelerator. With its construction, we gained the dual opportunities to advance the state of the art in accelerator technology with the machine itself and in particle physics with the experiments that became possible in a higher energy regime. There have been 43 experiments in the Tevatron fixed target program. Many of these are better described as experimental programs, each with a broad range of physics goals and results, and more than 100 collaborating physicists and engineers. The results of this program are three-fold: (1) new technologies in accelerators, beams and detectors which advanced the state of the art; (2) new experimental results published in the refereed physics journals; and (3) newly trained scientists who are both the next generation of particle physicists and an important part of the scientific, technical and educational backbone of the country as a whole. In this book they compile these results. There are sections from each experiment including what their physics goals and results were, what papers were published, and which students have received degrees. Summaries of these results from the program as a whole are quite interesting, but the physics results from this program are too broad to summarize globally. The most important of the results appear in later sections of this booklet.

  2. Synthetic Nano-Low Density Lipoprotein as Targeted Drug Delivery Vehicle for Glioblastoma Multiforme

    E-Print Network [OSTI]

    Nikanjam, Mina; Blakely, Eleanor A.; Bjornstad, Kathleen A.; Shu, Xiao; Budinger, Thomas F.; Forte, Trudy M.

    2006-01-01T23:59:59.000Z

    Synthetic Nano-Low Density Lipoprotein as Targeted Drugmicroemulsion; peptide; nano-low density lipoproteintherapeutic agents. A synthetic nano-LDL (nLDL) particle was

  3. Multi-target Linear-quadratic control problem: semi-infinite interval

    E-Print Network [OSTI]

    2011-09-15T23:59:59.000Z

    We consider multi-target linear-quadratic control problem on semi- infinite interval. We show that the problem can be reduced to a simple convex optimization...

  4. Multi-target Linear-quadratic control problem: semi-infinite interval

    E-Print Network [OSTI]

    L. Faybusovich

    2011-09-12T23:59:59.000Z

    Sep 12, 2011 ... Multi-target Linear-quadratic control problem: semi-infinite interval. L. Faybusovich (leonid.faybusovich.1 ***at*** nd.edu) T Mouktonglang...

  5. anti-cancer therapeutic target: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Page Last Page Topic Index 1 Helicobacter pylon: Therapeutic Targets CiteSeer Summary: Helicobacter pylori is now considered a major pathogen of the upper gastrointestinal...

  6. High-intensity laser-driven proton acceleration enhancement from hydrogen containing ultrathin targets

    SciTech Connect (OSTI)

    Dollar, F.; Reed, S. A.; Matsuoka, T.; Bulanov, S. S.; Chvykov, V.; Kalintchenko, G.; McGuffey, C.; Rousseau, P.; Thomas, A. G. R.; Willingale, L.; Yanovsky, V.; Krushelnick, K.; Maksimchuk, A. [Center for Ultrafast Optical Science, University of Michigan, Ann Arbor, Michigan 48109 (United States)] [Center for Ultrafast Optical Science, University of Michigan, Ann Arbor, Michigan 48109 (United States); Litzenberg, D. W. [Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109 (United States)] [Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109 (United States)

    2013-09-30T23:59:59.000Z

    Laser driven proton acceleration experiments from micron and submicron thick targets using high intensity (2 10{sup 21} W/cm{sup 2}), high contrast (10{sup ?15}) laser pulses show an enhancement of maximum energy when hydrogen containing targets were used instead of non-hydrogen containing. In our experiments, using thin (<1?m) plastic foil targets resulted in maximum proton energies that were consistently 20%100% higher than when equivalent thickness inorganic targets, including Si{sub 3}N{sub 4} and Al, were used. Proton energies up to 20 MeV were measured with a flux of 10{sup 7} protons/MeV/sr.

  7. Targets for Onboard Hydrogen Storage Systems for Light-Duty Vehicles...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    A detailed explanation of each target is given in the following pages. targetsonboardhydrostorageexplanation.pdf More Documents & Publications US DRIVE Hydrogen Storage...

  8. Application of 2D VSP Imaging Technology to the Targeting of...

    Open Energy Info (EERE)

    D VSP Imaging Technology to the Targeting of Exploration and Production Wells in a Basin and Range Geothermal System Humboldt House-Rye Patch Geothermal Area Geothermal Project...

  9. PROCEEDINGS OF THE SIXTH ANNUAL CONFERENCE OF THE INTERNATIONAL NUCLEAR TARGET DEVELOPMENT SOCIETY

    E-Print Network [OSTI]

    Authors, Various

    2011-01-01T23:59:59.000Z

    evaporating titanium and reacting the deposit in nitrogen atthe deposited titanium layer and the nitrogen diffused intogas take-up by titanium cones. Nitrogen Targets Produced By

  10. Characterization of LI+ Alumino-Silicate Ion Source for Target Heating Experiments

    E-Print Network [OSTI]

    Roy, P.K.

    2013-01-01T23:59:59.000Z

    OF LI + ALUMINO-SILICATE ION SOURCE FOR TARGET HEATINGcm) Li + doped alumino-silicate source to pro- duce shortdiameter lithium alumino-silicate ion source is presented.

  11. Diagnostic power of diffuse reflectance spectroscopy for targeted detection of breast lesions with microcalcifications

    E-Print Network [OSTI]

    Soares, Jaqueline S.

    Microcalcifications geographically target the location of abnormalities within the breast and are of critical importance in breast cancer diagnosis. However, despite stereotactic guidance, core needle biopsy fails to ...

  12. Targeted quantification of low ng/mL level proteins in human...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    depletion, sensitive detection of targeted proteins at 50-100 pgmL levels in human blood plasmaserum was demonstrated. However, immunoaffinity depletion is often associated...

  13. Application of 2D VSP Imaging Technology to the Targeting of...

    Broader source: Energy.gov (indexed) [DOE]

    Review Conf Presco Energy Structural Profile "High-Enthalpy" Targets Existing Wellfield ("medium-enthalpy") Block Model used for Finite-Difference Modeling of Seismic Response 8 |...

  14. Ranacyclins, a New Family of Short Cyclic Antimicrobial Peptides: Biological Function, Mode of Action, and Parameters Involved in Target Specificity,,@

    E-Print Network [OSTI]

    Pompeu Fabra, Universitat

    of Action, and Parameters Involved in Target Specificity,,@ M. Luisa Mangoni, Niv Papo, Giuseppina Mignogna

  15. MULTI-TARGET TRACKING AND IDENTIFICATION BY A VECTOR OF SENSORS Sahin Cem Geyik and Boleslaw K. Szymanski

    E-Print Network [OSTI]

    Varela, Carlos

    , environmental monitoring, product quality monitoring etc. Target tracking has been a frequent focus of research target in a monitored area [2]. Even if multiple target tracking is considered, it is often limited-1-4244-2677-5/08/$25.00 c 2008 IEEE of WSN's include various military and civilian applica- tions, such as target tracking

  16. The shape and size of crowding for moving targets Peter J. Bex *, Steven C. Dakin, Anita J. Simmers

    E-Print Network [OSTI]

    Bex, Peter

    (Bondarko & Danilova, 1997; Hess, Dakin, & Kapoor, 2000). How- ever, crowding also occurs between target

  17. Final report : Phase III targeted investigation, Everest, Kansas.

    SciTech Connect (OSTI)

    LaFreniere, L. M.; Environmental Science Division

    2006-01-31T23:59:59.000Z

    The Commodity Credit Corporation (CCC), an agency of the U.S. Department of Agriculture (USDA), formerly operated grain storage facilities at two different locations at Everest, Kansas (Figure 1.1). One facility (referred to in this report as the Everest facility) was at the western edge of the city. The second facility (referred to in this report as Everest East) was about 0.5 mi northeast of the town. The CCC/USDA operated these facilities from the early 1950s until the early 1970s, at a time when commercial fumigants containing carbon tetrachloride were in common use by the CCC/USDA and private industry for the preservation of grain in storage. In 1997 the Kansas Department of Health and Environment (KDHE) sampled several domestic drinking water and non-drinking water wells in the Everest area as part of the CCC/USDA Private Well Sampling Program. All of the sampled wells were outside the Everest city limits. Carbon tetrachloride contamination was identified at a single domestic drinking water well (the Nigh well, DW06; Figure 1.1) approximately 3/8 mi northwest of the former Everest CCC/USDA grain storage facility. Subsequent KDHE investigations suggested that the contamination in DW06 could be linked to the former use of grain fumigants at the CCC/USDA facility. For this reason, the CCC/USDA is conducting a phased environmental study to determine the source and extent of the carbon tetrachloride contamination at Everest and to identify potential remedial options. The studies are being performed by the Environmental Research Division of Argonne National Laboratory. Two phases of investigation were completed previously; this report presents the findings of the targeted Phase III investigation at Everest.

  18. The use of ground-penetrating radar with a cooperative target

    E-Print Network [OSTI]

    Allen, Christopher Thomas; Shi, K.; Plumb, R. G.

    1998-09-01T23:59:59.000Z

    are presented for a time-domain CT, a dipole antenna connected to an unterminated delay line. By using several independent time-domain CT's, strategically arrayed about a target, the rotational aspect of the target can also be obtained. Finally, harmonic...

  19. Blind Predictions of Local Protein Structure in CASP2 Targets Using the I-Sites Library

    E-Print Network [OSTI]

    Bystroff, Chris

    Blind Predictions of Local Protein Structure in CASP2 Targets Using the I-Sites Library Christopher ABSTRACT Blind predictions of the local structure of nine CASP2 targets were made using the I-sites library dataset to optimize the method may intro- duce a bias in favor of that set. Blind predictions of data

  20. PIER Demand Response Research Center SCOPING STUDY ROUNDTABLE RESEARCH TARGET AREAS

    E-Print Network [OSTI]

    PIER Demand Response Research Center SCOPING STUDY ROUNDTABLE ­ RESEARCH TARGET AREAS (Draft Areas #12;PIER Demand Response Research Center SCOPING STUDY ROUNDTABLE ­ RESEARCH TARGET AREAS (Draft the Value of Demand Response: Develop an Integrated Efficiency / Demand Response Framework Introduction

  1. A Constant Gain Kalman Filter Approach to target tracking in Wireless Sensor Networks

    E-Print Network [OSTI]

    Naik, Naren

    A Constant Gain Kalman Filter Approach to target tracking in Wireless Sensor Networks Ashwin Yadav1 domains. One of the most fundamen- tal and widely used approaches to target tracking is the Kalman filter. In presence of unknown noise statistics there are difficulties in the Kalman filter yielding good results

  2. TARGET TRACKING IN THE RECOMMENDER SPACE Toward a new recommender system based on Kalman filtering

    E-Print Network [OSTI]

    Paris-Sud XI, Universit de

    TARGET TRACKING IN THE RECOMMENDER SPACE Toward a new recommender system based on Kalman filtering, France Anne.boyer@loria.fr Keywords: Kalman filtering, target tracking, recommender systems. user tracking by Kalman filtering. We assume that users and their seen resources are vectors

  3. Calibration of broadband active acoustic systems using a single standard spherical target

    E-Print Network [OSTI]

    Stanton, Tim

    Calibration of broadband active acoustic systems using a single standard spherical target Timothy K 8 April 2008 When calibrating a broadband active acoustic system with a single standard target the concept of using this echo for calibration in the work of Dragonette et al. J. Acoust. Soc. Am. 69, 1186

  4. HERMES measurements of Collins and Sivers asymmetries from a transversely polarised hydrogen target

    E-Print Network [OSTI]

    Markus Diefenthaler

    2007-06-19T23:59:59.000Z

    Azimuthal single-spin asymmetries (SSA) in semi-inclusive electroproduction of pi-mesons and charged K-mesons in deep-inelastic scattering of positrons and electrons on a transversely polarised hydrogen target were observed. Significant SSA amplitudes for both the Collins and the Sivers mechanism are presented for the full data set recorded with transverse target polarisation at the HERMES experiment.

  5. Magnetized Target Fusion: Input to the 35-yr Fusion Long-Range Electric Plan

    E-Print Network [OSTI]

    controlled thermonuclear fusion in the laboratory -- Intermediate between MFE and IFE Presently only fundedMagnetized Target Fusion: Input to the 35-yr Fusion Long-Range Electric Plan G. A. Wurden Fusion Energy Program Office Los Alamos National Laboratory Jan. 14, 2003 #12;Magnetized Target Fusion: Input

  6. Comparisons on thin and thick neutron target for low energy proton beam

    SciTech Connect (OSTI)

    Zhong, B.; Yu, G.; Wang, X.; Wang, K. [Dept. of Engineering Physics, Tsinghua Univ., Beijing 100084 (China)

    2012-07-01T23:59:59.000Z

    As the progress on accelerator physics and neutronics, the compact neutron sources driven by low energy and high intensity beam are becoming extensively developed and researched all around the world. The neutron target of an accelerator driven neutron source is one of the key components, and the stability of the neutron target affect the operation and performance of the neutron facility. When a low energy proton is projected to the beryllium target, the main reaction is the inelastic scattering between the proton and extra-nuclear electrons. As the decreasing of proton energy, the rate of elastic scattering between proton and target nucleus begins to increase. When the energy of proton is very low, the pickup charge reaction begins to appear. Focus on the problems brought by high intensity proton beam such as proton implantation, radiation damages, heat deposition and gas production, we performed sufficient numerical simulations for both thin and thick target determined by proton range. The results show that the critical problem for thick target is the proton implantation, causing the forming of bubbles and beryllium flaked in vacuum. The thin target sacrifices a little neutron yield, but avoid the proton stopped in target, and decrease the radiation damage and energy deposition. (authors)

  7. KT McDonald MAP Spring Meeting May 30, 2014 1 Target System Concept

    E-Print Network [OSTI]

    McDonald, Kirk

    Issues for Solid Targets When beam pulse length t is less than target radius r divided by speed of sound/C, where E = modulus of elasticity. In many metals, the tensile strength obeys P 0.002 E, 10-5, and C 0

  8. Rain splash of dry sand revealed by high-speed imaging and sticky paper splash targets

    E-Print Network [OSTI]

    Rain splash of dry sand revealed by high-speed imaging and sticky paper splash targets David Jon by raindrop impacts. We use high-speed imaging of drop impacts on dry sand to describe the drop (2007), Rain splash of dry sand revealed by high-speed imaging and sticky paper splash targets, J

  9. Targets for Onboard Hydrogen Storage Systems for Light-Duty Vehicles

    Broader source: Energy.gov [DOE]

    This document describes the basis for the technical targets for onboard hydrogen storage for light-duty vehicles in the FCT Programs Multiyear Research, Development and Demonstration Plan. A detailed explanation of each target is given in the following pages.

  10. Accelerator-based neutron source using a cold deuterium target with degenerate electrons

    SciTech Connect (OSTI)

    Phillips, R. E.; Ordonez, C. A. [Department of Physics, University of North Texas, Denton, Texas 76203 (United States)] [Department of Physics, University of North Texas, Denton, Texas 76203 (United States)

    2013-07-15T23:59:59.000Z

    A neutron generator is considered in which a beam of tritons is incident on a hypothetical cold deuterium target with degenerate electrons. The energy efficiency of neutron generation is found to increase substantially with electron density. Recent reports of potential targets are discussed.

  11. Competition between color and luminance for target selection in smooth pursuit and saccadic

    E-Print Network [OSTI]

    Carrasco, Marisa

    Competition between color and luminance for target selection in smooth pursuit and saccadic eye of color and luminance for smooth pursuit and saccadic eye movements was investigated using a target selection paradigm. In two experiments, stimuli were varied along the dimensions color and luminance

  12. Statistical Approach to Radioactive Target Detection and Location via Wireless Sensor Networks

    E-Print Network [OSTI]

    Zhang, Tonglin

    Statistical Approach to Radioactive Target Detection and Location via Wireless Sensor Networks of radioactive target via wireless sensor networks. The statistical approach includes a hypotheses test this framework, a wireless sensor network (WSN) can be used as the system to obtain data. A statistical method

  13. Local Vote Decision Fusion for Target Detection in Wireless Sensor Networks

    E-Print Network [OSTI]

    Michailidis, George

    1 Local Vote Decision Fusion for Target Detection in Wireless Sensor Networks Natallia Katenka by a wireless sensor network. Sensors acquire measurements emitted from the target that are corrupted by noise Wireless sensor networks are widely used for monitoring natural phenomena in space and over time, as well

  14. T2K Target & Secondary Beamline -progress towards a neutrino Superbeam?

    E-Print Network [OSTI]

    McDonald, Kirk

    2008 Graphite to titanium diffusion bond Graphite-to-graphite bond Flow turns 180 at downstream window temperature Target rod completely encased in titanium to prevent oxidation of the graphite Helium cools both upstream and downstream titanium window first before cooling the target due to Ti-6Al-4V material

  15. EXPERIMENTAL EVALUATION OF SIMULTANEOUS 3D LOCALIZATION OF SENSOR NODES AND TRACKING MOVING TARGETS

    E-Print Network [OSTI]

    Instituto de Sistemas e Robotica

    EXPERIMENTAL EVALUATION OF SIMULTANEOUS 3D LOCALIZATION OF SENSOR NODES AND TRACKING MOVING TARGETS sensor/target localization) which rely on infrared (IR), radio frequency/received signal strength (RF of a simultaneous localization and track- ing (SLAT) algorithm for sensor networks, whose aim is to determine

  16. Measurement of azimuthal asymmetries associated with deeply virtual Compton scattering on a longitudinally polarized deuterium target

    E-Print Network [OSTI]

    The HERMES Collaboration; A. Airapetian; N. Akopov; Z. Akopov; E. C. Aschenauer; W. Augustyniak; R. Avakian; A. Avetissian; E. Avetisyan; S. Belostotski; N. Bianchi; H. P. Blok; A. Borissov; J. Bowles; I. Brodski; V. Bryzgalov; J. Burns; M. Capiluppi; G. P. Capitani; E. Cisbani; G. Ciullo; M. Contalbrigo; P. F. Dalpiaz; W. Deconinck; R. De Leo; L. De Nardo; E. De Sanctis; M. Diefenthaler; P. Di Nezza; M. Dueren; M. Ehrenfried; G. Elbakian; F. Ellinghaus; A. Fantoni; L. Felawka; S. Frullani; D. Gabbert; G. Gapienko; V. Gapienko; F. Garibaldi; G. Gavrilov; V. Gharibyan; F. Giordano; S. Gliske; M. Golembiovskaya; C. Hadjidakis; M. Hartig; D. Hasch; G. Hill; A. Hillenbrand; M. Hoek; Y. Holler; I. Hristova; Y. Imazu; A. Ivanilov; H. E. Jackson; A. Jgoun; H. S. Jo; S. Joosten; R. Kaiser; G. Karyan; T. Keri; E. Kinney; A. Kisselev; N. Kobayashi; V. Korotkov; V. Kozlov; B. Krauss; P. Kravchenko; V. G. Krivokhijine; L. Lagamba; R. Lamb; L. Lapikas; I. Lehmann; P. Lenisa; L. A. Linden-Levy; A. Lopez Ruiz; W. Lorenzon; X. -G. Lu; X. -R. Lu; B. -Q. Ma; D. Mahon; N. C. R. Makins; S. I. Manaenkov; L. Manfre; Y. Mao; B. Marianski; A. Martinez de la Ossa; H. Marukyan; C. A. Miller; A. Movsisyan; V. Muccifora; M. Murray; D. Mueller; A. Mussgiller; E. Nappi; Y. Naryshkin; A. Nass; M. Negodaev; W. -D. Nowak; L. L. Pappalardo; R. Perez-Benito; N. Pickert; M. Raithel; P. E. Reimer; A. R. Reolon; C. Riedl; K. Rith; G. Rosner; A. Rostomyan; J. Rubin; D. Ryckbosch; Y. Salomatin; F. Sanftl; A. Schaefer; G. Schnell; K. P. Schueler; B. Seitz; T. -A. Shibata; V. Shutov; M. Stancari; M. Statera; E. Steffens; J. J. M. Steijger; H. Stenzel; J. Stewart; F. Stinzing; S. Taroian; A. Terkulov; A. Trzcinski; M. Tytgat; A. Vandenbroucke; P. B. Van der Nat; Y. Van Haarlem; C. Van Hulse; D. Veretennikov; V. Vikhrov; I. Vilardi; C. Vogel; S. Wang; S. Yaschenko; Z. Ye; S. Yen; W. Yu; D. Zeiler; B. Zihlmann; P. Zupranski

    2011-05-02T23:59:59.000Z

    Azimuthal asymmetries in exclusive electroproduction of a real photon from a longitudinally polarized deuterium target are measured with respect to target polarization alone and with respect to target polarization combined with beam helicity and/or beam charge. The asymmetries appear in the distribution of the real photons in the azimuthal angle $\\phi$ around the virtual photon direction, relative to the lepton scattering plane. The asymmetries arise from the deeply virtual Compton scattering process and its interference with the Bethe-Heitler process. The results for the beam-charge and beam-helicity asymmetries from a tensor polarized deuterium target with vanishing vector polarization are shown to be compatible with those from an unpolarized deuterium target, which is expected for incoherent scattering dominant at larger momentum transfer. Furthermore, the results for the single target-spin asymmetry and for the double-spin asymmetry are found to be compatible with the corresponding asymmetries previously measured on a hydrogen target. For coherent scattering on the deuteron at small momentum transfer to the target, these findings imply that the tensor contribution to the cross section is small. Furthermore, the tensor asymmetry is found to be compatible with zero.

  17. CryPLH: Protecting smart energy systems from targeted attacks with a PLC honeypot

    E-Print Network [OSTI]

    Bencsáth, Boldizsár

    CryPLH: Protecting smart energy systems from targeted attacks with a PLC honeypot D´aniel Istv of control system elements, such as PLCs. In this paper, we design and implement the Crysys PLC honeypot (CryPLH) system to detect targeted attacks against industrial control systems. This PLC honeypot can

  18. Identification of novel Hoxa1 downstream targets regulating hindbrain, neural crest and inner ear development

    E-Print Network [OSTI]

    Capecchi, Mario R.

    Identification of novel Hoxa1 downstream targets regulating hindbrain, neural crest and inner ear and heart in humans and mice; however, almost nothing is known about the molecular downstream targets regulated by Hox genes (Hueber and Lohmann, 2008). In this study, we set out to identify the downstream

  19. Target Following Performance in the Presence of Latency, Jitter, and Signal Dropouts

    E-Print Network [OSTI]

    Strzlinger, Wolfgang

    Target Following Performance in the Presence of Latency, Jitter, and Signal Dropouts Andriy increase very quickly for latencies of over 110 ms, for latency jitters above 40 ms, and for dropout rates, latency jitter, dropouts, tracking, moving target. INDEX TERMS: H.5.2. [Information Interfaces

  20. Combining Area Patrol, Perimeter Surveillance, and Target Tracking Using Ordered Upwind Methods

    E-Print Network [OSTI]

    Frew, Eric W.

    in order to detect and classify adversarial targets. We distinguish this task from the commonly used term search to denote that the process is continual, i.e. regions must be sensed more than once goal of the surveillance task is insuring that targets cannot enter the region undetected. Finally

  1. Coupling time decoding and trajectory decoding using a target-included model in the motor cortex

    E-Print Network [OSTI]

    Wu, Wei

    Coupling time decoding and trajectory decoding using a target-included model in the motor cortex Communicated by D. Erdogmus Available online 27 December 2011 Keywords: Neural decoding Motor cortex Target made within the last decade in motor cortical decoding that predicts movement behaviors from population

  2. A High-Throughput Method to Examine Protein-Nucleotide Interactions Identifies Targets of the Bacterial

    E-Print Network [OSTI]

    A High-Throughput Method to Examine Protein- Nucleotide Interactions Identifies Targets can easily be applied to examine multiple protein-protein, protein-nucleotide and nucleotide-nucleotide Protein-Nucleotide Interactions Identifies Targets of the Bacterial Transcriptional Regulatory Protein Fur

  3. 1 INTRODUCTION 1 Predicting drug-target interactions for new drug compounds

    E-Print Network [OSTI]

    Marchiori, Elena

    1 INTRODUCTION 1 Predicting drug-target interactions for new drug compounds using a weighted@cs.ru.nl,elenam@cs.ru.nl Abstract In silico discovery of interactions between drug compounds and target proteins is of core importance for improving the efficiency of the laborious and costly experimental determination of drug

  4. DRUG-TARGET INTERACTION PREDICTION BY INTEGRATING CHEMICAL, GENOMIC, FUNCTIONAL AND PHARMACOLOGICAL DATA

    E-Print Network [OSTI]

    Zeng, Jianyang "Michael"

    DRUG-TARGET INTERACTION PREDICTION BY INTEGRATING CHEMICAL, GENOMIC, FUNCTIONAL AND PHARMACOLOGICAL.edu.cn Corresponding author In silico prediction of unknown drug-target interactions (DTIs) has become a popular tool for drug repositioning and drug development. A key challenge in DTI prediction lies in integrating multiple

  5. Modeling DT Vaporization and Melting in a Direct Drive Target B. R. Christensen1

    E-Print Network [OSTI]

    Raffray, A. René

    concept utilizes multiple laser beams to compress and heat small spherical targets loaded with fusion fuel (fig. 2). This simplifies both the heat conduction equation and the calculation of the deflection energy (IFE) direct drive targets are subjected to heating from energy exchange with the background gas

  6. Combined effects of prepulsing and target geometry on efficient extreme ultraviolet

    E-Print Network [OSTI]

    Harilal, S. S.

    and the deposition of EUV and out of band radiation can fur- ther cause surface erosion and damage at the required targets geometries with special grooves as developed previously by the authors. C 2011 Society of Photo-Optical. Damage of multilayer Mo/Si mirrors by the de- bris products of laser beam interaction with target

  7. Effects of Parameters on Nash Games with OSNR Target Department of Electrical and

    E-Print Network [OSTI]

    Pavel, Lacra

    Effects of Parameters on Nash Games with OSNR Target Yan Pan Department of Electrical and Computer of Electrical and Computer Engineering University of Toronto Toronto, ON M5S 3G4, Canada pavel of pric- ing mechanisms on system performance. We also show that OSNR target can be achieved

  8. Preliminary design studies for an iridium rod target at the BNL-AGS

    SciTech Connect (OSTI)

    Ludewig, H.; Hastings, J.; Montanez, P.; Todosow, M.

    1998-12-31T23:59:59.000Z

    The BNL-AGS is an intense source of 24 GeV protons. It is proposed to explore the potential to use these protons as the driver for a Pulsed Spallation Neutron Source target. The proposed target design is based on an edge cooled iridium rod concept--similar to the anti-proton production target which operated reliably at CERN under similar conditions. Lead, lead fluoride, and beryllium are investigated as possible reflector materials, and ambient temperature light water and 80 K light water ice are proposed as initial moderator materials. Both moderators are decoupled by cadmium containing moderator chamber walls. The small size of the target has the advantage that the moderators can be placed close to the target (resulting in a bright source), and since a large fraction of the radioactive inventory is contained in the iridium rod, removal and disposition of this inventory should be relatively simple and inexpensive.

  9. Preparation and characterisation of isotopically enriched Ta$_2$O$_5$ targets for nuclear astrophysics studies

    E-Print Network [OSTI]

    A. Caciolli; D. A. Scott; A. Di Leva; A. Formicola; M. Aliotta; M. Anders; A. Bellini; D. Bemmerer; C. Broggini; M. Campeggio; P. Corvisiero; R. Depalo; Z. Elekes; Zs. Flp; G. Gervino; A. Guglielmetti; C. Gustavino; Gy. Gyrky; G. Imbriani; M. Junker; M. Marta; R. Menegazzo; E. Napolitani; P. Prati; V. Rigato; V. Roca; C. Rolfs; C. Rossi Alvarez; E. Somorjai; C. Salvo; O. Straniero; F. Strieder; T. Szcs; F. Terrasi; H. P. Trautvetter; D. Trezzi

    2012-10-01T23:59:59.000Z

    The direct measurement of reaction cross sections at astrophysical energies often requires the use of solid targets of known thickness, isotopic composition, and stoichiometry that are able to withstand high beam currents for extended periods of time. Here, we report on the production and characterisation of isotopically enriched Ta$_2$O$_5$ targets for the study of proton-induced reactions at the Laboratory for Underground Nuclear Astrophysics facility of the Laboratori Nazionali del Gran Sasso. The targets were prepared by anodisation of tantalum backings in enriched water (up to 66% in $^{17}$O and up to 96% in $^{18}$O). Special care was devoted to minimising the presence of any contaminants that could induce unwanted background reactions with the beam in the energy region of astrophysical interest. Results from target characterisation measurements are reported, and the conclusions for proton capture measurements with these targets are drawn.

  10. Preparation and characterisation of isotopically enriched Ta$_2$O$_5$ targets for nuclear astrophysics studies

    E-Print Network [OSTI]

    Caciolli, A; Di Leva, A; Formicola, A; Aliotta, M; Anders, M; Bellini, A; Bemmerer, D; Broggini, C; Campeggio, M; Corvisiero, P; Depalo, R; Elekes, Z; Flp, Zs; Gervino, G; Guglielmetti, A; Gustavino, C; Gyrky, Gy; Imbriani, G; Junker, M; Marta, M; Menegazzo, R; Napolitani, E; Prati, P; Rigato, V; Roca, V; Rolfs, C; Alvarez, C Rossi; Somorjai, E; Salvo, C; Straniero, O; Strieder, F; Szcs, T; Terrasi, F; Trautvetter, H P; Trezzi, D

    2012-01-01T23:59:59.000Z

    The direct measurement of reaction cross sections at astrophysical energies often requires the use of solid targets of known thickness, isotopic composition, and stoichiometry that are able to withstand high beam currents for extended periods of time. Here, we report on the production and characterisation of isotopically enriched Ta$_2$O$_5$ targets for the study of proton-induced reactions at the Laboratory for Underground Nuclear Astrophysics facility of the Laboratori Nazionali del Gran Sasso. The targets were prepared by anodisation of tantalum backings in enriched water (up to 66% in $^{17}$O and up to 96% in $^{18}$O). Special care was devoted to minimising the presence of any contaminants that could induce unwanted background reactions with the beam in the energy region of astrophysical interest. Results from target characterisation measurements are reported, and the conclusions for proton capture measurements with these targets are drawn.

  11. Process and targets for production of no-carrier-added radiotin

    DOE Patents [OSTI]

    Srivastava, Suresh C; Zhuikov, Boris Leonidovich; Ermolaev, Stanislav Victorovich; Konyakhin, Nikolay Alexandrovich; Kokhanyuk, Vladimir Mikhailovich; Khamyanov, Stepan Vladimirovich; Togaeva, Natalya Roaldovna

    2014-04-22T23:59:59.000Z

    One embodiment of the present invention includes a process for production and recovery of no-carrier-added radioactive tin (NCA radiotin). An antimony target can be irradiated with a beam of accelerated particles forming NCA radiotin, followed by separation of the NCA radiotin from the irradiated target. The target is metallic Sb in a hermetically sealed shell. The shell can be graphite, molybdenum, or stainless steel. The irradiated target can be removed from the shell by chemical or mechanical means, and dissolved in an acidic solution. Sb can be removed from the dissolved irradiated target by extraction. NCA radiotin can be separated from the remaining Sb and other impurities using chromatography on silica gel sorbent. NCA tin-117m can be obtained from this process. NCA tin-117m can be used for labeling organic compounds and biological objects to be applied in medicine for imaging and therapy of various diseases.

  12. Minor Actinide Recycle in Sodium Cooled Fast Reactors Using Heterogeneous Targets

    SciTech Connect (OSTI)

    Samuel Bays; Pavel Medvedev; Michael Pope; Rodolfo Ferrer; Benoit Forget; Mehdi Asgari

    2009-04-01T23:59:59.000Z

    This paper investigates the plausible design of transmutation target assemblies for minor actinides (MA) in Sodium Fast Reactors (SFR). A heterogeneous recycling strategy is investigated, whereby after each reactor pass, un-burned MAs from the targets are blended with MAs produced by the driver fuel and additional MAs from Spent Nuclear Fuel (SNF). A design iteration methodology was adopted for customizing the core design, target assembly design and matrix composition design. The overall design was constrained against allowable peak or maximum in-core performances. While respecting these criteria, the overall design was adjusted to reduce the total number of assemblies fabricated per refueling cycle. It was found that an inert metal-hydride MA-Zr-Hx target matrix gave the highest transmutation efficiency, thus allowing for the least number of targets to be fabricated per reactor cycle.

  13. Trapped Between Two Tails: Trading Off Scientific Uncertainties via Climate Targets

    SciTech Connect (OSTI)

    Lemoine, Derek M.; McJeon, Haewon C.

    2013-08-20T23:59:59.000Z

    Climate change policies must trade off uncertainties about future warming, about the social and ecological impacts of warming, and about the cost of reducing greenhouse gas emissions. We show that laxer carbon targets produce broader distributions for climate damages, skewed towards severe outcomes. However, if potential low-carbon technologies fill overlapping niches, then more stringent carbon targets produce broader distributions for the cost of reducing emissions, skewed towards high-cost outcomes. We use the technology- rich GCAM integrated assessment model to assess the robustness of 450 ppm and 500 ppm carbon targets to each uncertain factor. The 500 ppm target provides net benefits across a broad range of futures. The 450 ppm target provides net benefits only when impacts are greater than conventionally assumed, when multiple technological breakthroughs lower the cost of abatement, or when evaluated with a low discount rate. Policy evaluations are more sensitive to uncertainty about abatement technology and impacts than to uncertainty about warming.

  14. Breakthroughs in Seismic and Borehole Characterization of Basalt Sequestration Targets

    SciTech Connect (OSTI)

    Sullivan, E. C.; Hardage, Bob A.; McGrail, B. Peter; Davis, Klarissa N.

    2011-04-01T23:59:59.000Z

    Mafic continental flood basalts form a globally important, but under-characterized CO2 sequestration target. The Columbia River Basalt Group (CRBG) in the northwestern U.S. is up to 5 km thick and covers over 168,000 km2. In India, flood basalts are 3 km thick and cover greater than 500,000 km2. Laboratory experiments demonstrate that the CRBG and other basalts react with formation water and super critical (sc) CO2 to precipitate carbonates, thus adding a potential mineral trapping mechanism to the standard trapping mechanisms of most other types of CO2 sequestration reservoirs. Brecciated tops of individual basalt flows in the CRBG form regional aquifers that locally have greater than 30% porosity and three Darcies of permeability. Porous flow tops are potential sites for sequestration of gigatons of scCO2 in areas where the basalts contain unpotable water and are at depths greater than 800 m. In this paper we report on the U.S. DOE Big Sky Regional Carbon Sequestration Partnership surface seismic and borehole geophysical characterization that supports a field test of capacity, integrity, and geochemical reactivity of CRBG reservoirs in eastern Washington, U.S.A. Traditional surface seismic methods have had little success in imaging basalt features in on-shore areas where the basalt is thinly covered by sediment. Processing of the experimental 6.5 km, 5 line 3C seismic swath included constructing an elastic wavefield model, identifying and separating seismic wave modes, and processing the swath as a single 2D line. Important findings include: (1) a wide variety of shear wave energy modes swamp the P-wave seismic records; (2) except at very short geophone offsets, ground roll overprints P-wave signal; and (3) because of extreme velocity contrasts, P-wave events are refracted at incidence angles greater than 7-15 degrees. Subsequent removal of S-wave and other noise during processing resulted in tremendous improvement in image quality. The application of wireline logging to onshore basalts is underexploited. Full waveform sonic logs and resistivity-based image logs acquired in the 1250 m basalt pilot borehole provide powerful tools for evaluating geomechanics and lithofacies. The azimuth of the fast shear wave is parallel to SH and records the changes through time in basalt flow and tectonic stress tensors. Combined with image log data, azimuthal S-wave data provide a borehole technique for assessing basalt emplacement and cooling history that is related to the development of reservoirs and seals, as well as the orientation of tectonic stresses and fracture systems that could affect CO2 transport or containment. Reservoir and seal properties are controlled by basalt lithofacies, and rescaled P- and S- wave slowness curves, integrated with image logs, provide a tool for improved recognition of subsurface lithofacies.

  15. Energetic protons from an ultraintense laser interacting with a symmetric parabolic concave target

    SciTech Connect (OSTI)

    Ali Bake, Muhammad; Xie Baisong [Key Laboratory of Beam Technology and Materials Modification of the Ministry of Education, College of Nuclear Science and Technology, Beijing Normal University, Beijing 100875 (China); Shan Zhang [Department of Mathematics and Physics, Shijiazhuang Tiedao University, Shijiazhuang 050043 (China); Wang Hongyu [Department of Physics, Anshan Normal University, Anshan 114005 (China); Shanghai Bright-Tech Information Technology Co. Ltd, Shanghai 200136 (China)

    2013-03-15T23:59:59.000Z

    A scheme of a symmetric parabolic concave target irradiated by an ultraintense laser for efficient proton acceleration is proposed and involved problem is studied by using two-dimensional particle-in-cell (PIC) simulations. Results indicate that on one hand, the laser field is focused by the front parabolic concave surface of target and, on the other hand, more energetic hot electrons will traverse to the rear surface of target due to concave shape. The space-charge-separation field, induced by those hot electrons escaping form parabolic concave rear surface of target, can accelerate protons to relatively high energy with narrow energy spread. The dependence of the efficiency of proton acceleration on the target parameters is examined, and the optimal target parameters are obtained. Particle-in-cell simulations show that the proton peak energy and energy spread are greatly enhanced when the target parameters are chosen optimal, for example, a proton bunch with the maximum energy {approx}27.5 MeV and energy spread {approx}7% can be generated. Some implications of our results to experiments and comparisons with the other works are also discussed briefly.

  16. A liquid helium target system for a measurement of parity violation in neutron spin rotation

    E-Print Network [OSTI]

    C. D. Bass; T. D. Bass; B. R. Heckel; C. R. Huffer; D. Luo; D. M. Markoff; A. M. Micherdzinska; W. M. Snow; H. E. Swanson; S. C. Walbridge

    2009-09-17T23:59:59.000Z

    A liquid helium target system was designed and built to perform a precision measurement of the parity-violating neutron spin rotation in helium due to the nucleon-nucleon weak interaction. The measurement employed a beam of low energy neutrons that passed through a crossed neutron polarizer--analyzer pair with the liquid helium target system located between them. Changes between the target states generated differences in the beam transmission through the polarizer--analyzer pair. The amount of parity-violating spin rotation was determined from the measured beam transmission asymmetries. The expected parity-violating spin rotation of order $10^{-6}$ rad placed severe constraints on the target design. In particular, isolation of the parity-odd component of the spin rotation from a much larger background rotation caused by magnetic fields required that a nonmagnetic cryostat and target system be supported inside the magnetic shielding, while allowing nonmagnetic motion of liquid helium between separated target chambers. This paper provides a detailed description of the design, function, and performance of the liquid helium target system.

  17. Clinical Evaluation of Stereotactic Target Localization Using 3-Tesla MRI for Radiosurgery Planning

    SciTech Connect (OSTI)

    MacFadden, Derek [University of Toronto Faculty of Medicine, Toronto, ON (Canada); Zhang Beibei; Brock, Kristy K. [Radiation Medicine Program, Princess Margaret Hospital, University Health Network, Toronto, ON (Canada); Hodaie, Mojgan [Division of Neurosurgery, Toronto Western Hospital, Toronto, ON (Canada); Laperriere, Normand [Radiation Medicine Program, Princess Margaret Hospital, University Health Network, Toronto, ON (Canada); Department of Radiation Oncology, University of Toronto, Toronto, ON (Canada); Schwartz, Michael [Division of Neurosurgery, Toronto Western Hospital, Toronto, ON (Canada); Tsao, May [Department of Radiation Oncology, University of Toronto, Toronto, ON (Canada); Department of Radiation Oncology, Sunnybrook Regional Cancer Centre, Toronto, ON (Canada); Stainsby, Jeffrey [Applied Science Laboratories, GE Healthcare, Mississauga, ON (Canada); Lockwood, Gina [Radiation Medicine Program, Princess Margaret Hospital, University Health Network, Toronto, ON (Canada); Mikulis, David [Department of Medical Imaging, University Health Network, Toronto, ON (Canada); Menard, Cynthia, E-mail: cynthia.menard@rmp.uhn.on.c [Radiation Medicine Program, Princess Margaret Hospital, University Health Network, Toronto, ON (Canada); Department of Radiation Oncology, University of Toronto, Toronto, ON (Canada)

    2010-04-15T23:59:59.000Z

    Purpose: Increasing the magnetic resonance imaging (MRI) field strength can improve image resolution and quality, but concerns remain regarding the influence on geometric fidelity. The objectives of the present study were to spatially investigate the effect of 3-Tesla (3T) MRI on clinical target localization for stereotactic radiosurgery. Methods and Materials: A total of 39 patients were enrolled in a research ethics board-approved prospective clinical trial. Imaging (1.5T and 3T MRI and computed tomography) was performed after stereotactic frame placement. Stereotactic target localization at 1.5T vs. 3T was retrospectively analyzed in a representative cohort of patients with tumor (n = 4) and functional (n = 5) radiosurgical targets. The spatial congruency of the tumor gross target volumes was determined by the mean discrepancy between the average gross target volume surfaces at 1.5T and 3T. Reproducibility was assessed by the displacement from an averaged surface and volume congruency. Spatial congruency and the reproducibility of functional radiosurgical targets was determined by comparing the mean and standard deviation of the isocenter coordinates. Results: Overall, the mean absolute discrepancy across all patients was 0.67 mm (95% confidence interval, 0.51-0.83), significantly <1 mm (p < .010). No differences were found in the overall interuser target volume congruence (mean, 84% for 1.5T vs. 84% for 3T, p > .4), and the gross target volume surface mean displacements were similar within and between users. The overall average isocenter coordinate discrepancy for the functional targets at 1.5T and 3T was 0.33 mm (95% confidence interval, 0.20-0.48), with no patient-specific differences between the mean values (p >.2) or standard deviations (p >.1). Conclusion: Our results have provided clinically relevant evidence supporting the spatial validity of 3T MRI for use in stereotactic radiosurgery under the imaging conditions used.

  18. Thermal-hydraulic analysis of the LANL/IPPE/EDO-GP 1-MW LBE target

    SciTech Connect (OSTI)

    He, X.; Ammerman, C.; Woloshun, K.; Li, N.

    2000-07-01T23:59:59.000Z

    The accelerator-driven transmutation of waste (ATW) concept has been proposed by the United States and other countries to transmute plutonium, higher actinides, and other environmentally hazardous fission products. One of the key components in the ATW concept is a target that, via spallation, produces neutrons to transmute nuclear waste. Since significant heat is generated during fissioning of the waste actinides, an efficient heat removal system is necessary. Liquid lead-bismuth eutectic (LBE) is an efficient coolant as well as a good spallation target for production of neutrons. The LBE coolant technology has been successfully used in Russian submarine nuclear reactors. The International Science and Technology Center (ISTC) has funded the Institute of Physics and Power Engineering (IPPE) and the Experiment and Design Organization-Gidropress (EDO-GP) of Russia to design and manufacture a pilot target (Target Circuit One-TC1) that incorporates Russian LBE technology into the ATW concept. The target will be tested in the 800-MeV, 1-mA proton beam at the Los Alamos National Laboratory (LANL) in 2 yr. These target experiments will provide valuable information on the performance of LBE as both spallation target and coolant. They will also help to design target/blanket systems for future ATW facilities. In summary, the authors have carried out thermal-hydraulic analyses for the LANL/IPPE/EDO-GP 1-MW LBE target. It is shown that the current design is suitable for the beam-on tests. The diffuser plate successfully enhances the coolant flow around the window center but still avoids generating recirculation zone downstream. The temperature range is within the proper operation range for both the LBE coolant and the structural materials.

  19. Continuing investigations for technology assessment of /sup 99/Mo production from LEU (low enriched Uranium) targets

    SciTech Connect (OSTI)

    Vandergrift, G.F.; Kwok, J.D.; Marshall, S.L.; Vissers, D.R.; Matos, J.E.

    1987-01-01T23:59:59.000Z

    Currently much of the world's supply of /sup 99m/Tc for medical purposes is produced from /sup 99/Mo derived from the fissioning of high enriched uranium (HEU). The need for /sup 99m/Tc is continuing to grow, especially in developing countries, where needs and national priorities call for internal production of /sup 99/Mo. This paper presents the results of our continuing studies on the effects of substituting low enriched Uranium (LEU) for HEU in targets for the production of fission product /sup 99/Mo. Improvements in the electrodeposition of thin films of uranium metal are reported. These improvements continue to increase the appeal for the substitution of LEU metal for HEU oxide films in cylindrical targets. The process is effective for targets fabricated from stainless steel or hastaloy. A cost estimate for setting up the necessary equipment to electrodeposit uranium metal on cylindrical targets is reported. Further investigations on the effect of LEU substitution on processing of these targets are also reported. Substitution of uranium silicides for the uranium-aluminum alloy or uranium aluminide dispersed fuel used in other current target designs will allow the substitution of LEU for HEU in these targets with equivalent /sup 99/Mo-yield per target and no change in target geometries. However, this substitution will require modifications in current processing steps due to (1) the insolubility of uranium silicides in alkaline solutions and (2) the presence of significant quantities of silicate in solution. Results to date suggest that both concerns can be handled and that substitution of LEU for HEU can be achieved.

  20. A study of lithium deuteride as a material for a polarized target

    E-Print Network [OSTI]

    Bltmann, S; Day, D B; Fatemi, R D; Gardner, B; Harris, C M; Johnson, J R; Mccarthy, J S; McKee, P M; Meyer, Werner T; Penttilae, S I; Ponikvar, E; Rijllart, A; Rondon, Oscar A; Lorant, S S; Tobias, W A; Trentalange, S; Zhu, H; Zihlmann, B; Zimmermann, D

    1999-01-01T23:59:59.000Z

    Experiment E155 at the Stanford Linear Accelerator Center (SLAC) measured the spin-dependent structure of the proton and neutron, using for the first time sup 6 LiD as the polarized deuteron target material in a high-energy electron beam. This compound provides a significantly higher dilution factor than any other solid deuteron target material currently used in high-energy physics experiments. Results of the polarization behavior of the sup 6 LiD target material before and after exposure to the 50 GeV/c electron beam used in E155 are presented.