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1

Towards isolation of the gene for X-linked retinitis pigmentosa (RP3)  

Science Conference Proceedings (OSTI)

Until recently the region of interest containing the gene for X-linked retinitis pigmentosa (RP3) was thought to lie between CYBB (Xp21.1) and the proximal end of the deletion in patient BB (JBBprox). This region was thought to span 100-150 kb. Here we present new mapping data to show that the distance between the 5{prime} (most proximal) end of CYBB and JBBprox is only 50 kb. Recently Roux et al. (1994) have described the isolation of a gene within this region but this showed no disease-associated changes. Further evidence from mapping the deletion in patient NF (who suffered from McLead`s syndrome and CGD but not RP) and from linkage analysis of our RP3 families with a new dinucleotide repeat suggests that the gene must extend proximally from JBBprox. In order to extend the region of search we have constructed a YAC contig spanning 800 kb to OTC. We are continuing our search for the RP3 gene using a variety of strategies including exon trapping and cDNA enrichment as well as direct screening of cDNA libraries with subclones from this region.

Dry, K.L.; Aldred, M.A.; Hardwick, L.J. [MRC Human Genetics Unit, Scotland (United Kingdom)] [and others

1994-09-01T23:59:59.000Z

2

Retinal Diseases: Age-Related Macular Degeneration and Retinitis Pigmentosa  

NLE Websites -- All DOE Office Websites (Extended Search)

Retinal Diseases: Age-Related Macular Degeneration and Retinitis Pigmentosa Retinal Diseases: Age-Related Macular Degeneration and Retinitis Pigmentosa Age-related macular degeneration (AMD) is an eye disease primarily affecting the central vision regions in people age 60 and older. According to the Macular Degeneration Research Fund, a case of AMD is diagnosed in the United States every 3 minutes. Each year, 1.2 million of the estimated 12 million people with AMD will suffer severe vision loss. Patients with AMD have dark areas in their vision caused by fluid leakage or bleeding in the macula, the center of the retina that produces the sharpest vision. The brain initially compensates for these dark patches. Early cellular dysfunction or spotting in the macula may go undetected until the disease is in advanced stages.

3

Prurigo pigmentosa treated with doxycycline  

E-Print Network (OSTI)

to minocycline [ 2 ]. Doxycycline has been reported to besuccessfully with doxycycline. References 1. Nagashima M.pigmentosa treated with doxycycline Tugba Rezan Ekmekci,

Ekmekci, Tugba Rezan; Altunay, Ilknur Kivanc; Koslu, Adem

2006-01-01T23:59:59.000Z

4

Prurigo pigmentosa: Report of two cases in the United States and review of the literature  

E-Print Network (OSTI)

pigmentosa treated with doxycycline. Dermatol Online J 2006tetracyclines such as doxycycline and minocycline, as well

Whang, Talley; Kirkorian, A Yasmine; Krishtul, Anna; Phelps, Robert; Shim-Chang, Helen

2011-01-01T23:59:59.000Z

5

RP-5 RENEWABLE ENERGY PROJECT  

SciTech Connect

This is the second quarterly technical report for the RP-5 Renewable Energy Project. The report summarizes the work progress, effort and activities that took place during the period of October 1, 2002 to December 31, 2002. The report has been prepared in accordance with the Department of Energy (DOE) Guidelines. This technical report covers all meetings and discussions that were conducted in order to follow up on potential renewable energy technologies that were identified in the previous report; the technologies were analyzed for their feasibility, suitability and cost effectiveness for this project. This report covers the one-day conceptual design kickoff meeting that took place on November 4, 2002. The meeting was held to discuss the practicality and implementation of potential innovative technologies. Following the kickoff meeting, Inland Empire Utilities Agency (IEUA) and CH2M Hill, the Public Interest Energy Research (PIER) Consultant, held a meeting on December 2, 2002 to discuss the Conceptual Design Report outline and contents in order to clearly present each selected technology along with its evaluation, cost effectiveness and justification. A conference call also took place between the PIER Consultant and IEUA on December 13, 2002, to discuss the overall scope of work for this project. Major project activities in this period include expanded discussions on previous Energy Charrette decisions and recommendations, conceptual design kickoff meeting, conceptual design report, and deciding on the overall project scope of work.

Neil Clifton; Eliza Jane Whitman; Jamal A. Zughbi

2003-01-30T23:59:59.000Z

6

Nucleosynthesis and the rp-process  

Science Conference Proceedings (OSTI)

Production of elements heavier than iron, their abundance and cite of production remain an active field of research to-date. In this paper I would present a brief review of the nucleosynthesis process and then focus further on the proton capture processes with particular emphasis on the nuclear physics aspects of the rp-process. The present calculation clearly shows that the electron capture rates on waiting point nuclei are at least of similar magnitude as the competing positron decay rates under rp-process conditions. The study strongly suggests that electron capture rates form an integral part of weak-interaction mediated rates under rp-process conditions and should not be neglected in nuclear reaction network calculations as done in past.

Nabi, Jameel-Un [Faculty of Engineering Sciences, GIK Institute of Engineering Sciences and Technology, Topi 23640, Swabi, Khyber Pakhtunkhwa (Pakistan)

2012-11-20T23:59:59.000Z

7

RP-5 Renewable Energy Efficiency Project  

Science Conference Proceedings (OSTI)

This is the final technical report for the RP-5 Renewable Energy Efficiency Project (REEP). The report summarizes, in a comprehensive manner, all the work performed during the award period extending between July 12, 2002 and June 30, 2007. This report has been prepared in accordance with the Department of Energy (DOE) Guidelines and summarizes all of the activities that occurred during the award period. The RP-5 Renewable Energy Efficiency Project, under development by the Inland Empire Utilities Agency (IEUA), is comprised of a series of full-scale demonstration projects that will showcase innovative combinations of primary and secondary generation systems using methane gas derived from local processing of biosolids, dairy manure and other organic material. The goal of the project is to create renewable energy-based generation systems with energy efficiencies 65% or more. The project was constructed at the 15 MGD Regional Wastewater Treatment Plant No. 5 located in the City of Chino in California where the Agency has constructed its new energy-efficient (platinum-LEED rating) headquarters building. Technologies that were featured in the project include internal combustion engines (ICE), absorption chillers, treatment plant secondary effluent cooling systems, heat recovery systems, thermal energy storage (TES), Organic Rankine Cycle (ORC) secondary power generation system, the integration of a future fuel cell system, gas cleaning requirements, and other state-of-the-art design combinations. The RP-5 REEP biogas source is coming from three manure digesters which are located within the RP-5 Complex and are joined with the RP-5 REEP through gas conveyance pipelines. Food waste is being injected into the manure digesters for digester gas production enhancement. The RP-5 REEP clearly demonstrates the biogas production and power generation viability, specifically when dealing with renewable and variable heating value (Btu) fuel. The RP-5 REEP was challenged with meeting stringent utility, gas, power, and air quality rules and regulations. Coordination with the Southern California Gas Company (SCGC), Southern California Edison (SCE), and South Coast Air Quality Management District (SCAQMD) was continuous and extensive. The interconnecting agreement and the permit to construct and operate were major obstacles despite the early start and coordination with the utility companies and regulatory agencies. The RP-5 REEP is part of a unique RP-5 Complex approach where several facilities are tied and connected with each other; where energy and gas can be transferred from one facility to another (see attached RP-5 Complex Ultimate Energy Balance Diagram). The REEP also incorporated new technologies, such as TES and ORC, along with using heat recovery for the platinum-LEED headquarter buildings heating and cooling via efficient absorption chillers. Through the conceptual design phase, numerous innovative technologies were researched and evaluated, with the most proven and efficient selected to be part of the RP-5 REEP.

Neil Clifton; Dave Wall; Jamal Zughbi

2007-06-30T23:59:59.000Z

8

enter part number BNC / RP-BNC  

E-Print Network (OSTI)

enter part number Products 7/16 1.0/2.3 1.6/5.6 AFI AMC BNC / RP-BNC C FAKRA SMB FME HN MCX Mini ------- Product Search ------- Inventory Search Search Results for: 31-10152-RFX Results: 1 - 1 of 1 Part Number. All rights reserved. Copyright | Terms & Conditions | RF E-Mail Client | Contact Us | Amphenol

Berns, Hans-Gerd

9

RP-5 Renewable Energy Efficiency Project  

Science Conference Proceedings (OSTI)

This is the sixth quarterly technical report for the RP-5 Renewable Energy Efficiency Project. The report summarizes the work progress, effort and activities that took place during the period from October 1, 2003 through December 31, 2003. The report has been prepared in accordance with the Department of Energy (DOE) Guidelines. In coordination with the DOE, IEUA has revised the original Cooperative Agreement to reflect the actual and current project scope of work. The original Agreement statement of work (SOW) included conceptual and preliminary equipment and systems, which were further evaluated for feasibility and suitability for the project. As a result, some of the equipment was taken out of the project scope. In response to questions from the DOE, IEUA has submitted a summary report on the Organic Rankine Cycle (ORC) secondary power generation units for availability and suitability for this project and associated safety concerns pointed out by the DOE. IEUA has awarded the consulting engineering contract to Parsons Water and Infrastructure, Inc. to provide the project's design and construction services. The project's pre-design kickoff meeting was held at IEUA's headquarters on December 11, 2003. IEUA has submitted a proposal for a grant offered by California Energy Commission (CEC) which if awarded to IEUA, will add value to this project. IEUA has finalized and signed the agreement with Stirling Energy Systems (SES) to host a 25 kW Stirling Engine at the RP-5 plant site for reliability and performance testing using digester and natural gas. As a result of further evaluation of the flexible microturbine system, IEUA has decided to take it out of the project's scope of work; however, it may be considered in future projects at other locations. IEUA has installed a 60 kW Photovoltaic (PV) power generation system on the roof of the new headquarters building. A matching funds update is also included in the Results and Discussion section. The update presents the work effort performed by CH2M Hill, the PIER Consultant, and the associated costs that serve as matching funds for the RP-5 Renewable Energy Efficiency Project during this report period.

Neil Clifton; Eliza Jane Whitman; Jamal A. Zughbi

2004-01-29T23:59:59.000Z

10

Using Resistance Heating to Create Full-Scale API RP2Z CTOD ...  

Science Conference Proceedings (OSTI)

Abstract Scope, API RP2Z testing is used by the oil and gas industry to qualify steel ... Additionally, the current RP2Z welding procedure may not lead to uniform ...

11

Flexible retinal electrode array  

DOE Patents (OSTI)

An electrode array which has applications for neural stimulation and sensing. The electrode array can include a large number of electrodes each of which is flexibly attached to a common substrate using a plurality of springs to allow the electrodes to move independently. The electrode array can be formed from a combination of bulk and surface micromachining, with electrode tips that can include an electroplated metal (e.g. platinum, iridium, gold or titanium) or a metal oxide (e.g. iridium oxide) for biocompatibility. The electrode array can be used to form a part of a neural prosthesis, and is particularly well adapted for use in an implantable retinal prosthesis where the electrodes can be tailored to provide a uniform gentle contact pressure with optional sensing of this contact pressure at one or more of the electrodes.

Okandan, Murat (Albuquerque, NM); Wessendorf, Kurt O. (Albuquerque, NM); Christenson, Todd R. (Albuquerque, NM)

2006-10-24T23:59:59.000Z

12

DE-RP52-08NA28091  

NLE Websites -- All DOE Office Websites (Extended Search)

8NA28091 8NA28091 [Submit in Volume I, TAB 2] Attachment L-1 Page 1 of 4 CORPORATE, PARTNERSHIP, JOINT VENTURE CERTIFICATES If the offer is submitted by a corporation, partnership or a Joint Venture, the applicable form provided on the following pages must be completed and submitted in Volume I of the proposal. In the alternative, other evidence must be submitted to substantiate the authority of the person signing the offer. If a corporation, the same officer shall not execute both the offer and the certificate. DE-RP52-08NA28091 [Submit in Volume I, TAB 2] Attachment L-1 Page 2 of 4 CORPORATE CERTIFICATE I, _______________________________________________, certify that I am the Secretary of the

13

Blood vessel segmentation methodologies in retinal images - A survey  

Science Conference Proceedings (OSTI)

Retinal vessel segmentation algorithms are a fundamental component of automatic retinal disease screening systems. This work examines the blood vessel segmentation methodologies in two dimensional retinal images acquired from a fundus camera and a survey ... Keywords: Blood vessel segmentation, Image segmentation, Medical imaging, Retinal images, Retinopathy, Survey

M. M. Fraz; P. Remagnino; A. Hoppe; B. Uyyanonvara; A. R. Rudnicka; C. G. Owen; S. A. Barman

2012-10-01T23:59:59.000Z

14

SRNS-RP-2013-00005 Savannah River Site Ten Year Site Plan FY  

NLE Websites -- All DOE Office Websites (Extended Search)

SRNS-RP-2013-00005 SRNS-RP-2013-00005 Savannah River Site Ten Year Site Plan FY 2014 - 2023 May 2013 United States Department of Energy Savannah River Site Ten Year Site Plan FY 2014 - 2023 May 2013 Prepared by: Savannah River Nuclear Solutions, LLC A Fluor Daniel Partnership Savannah River Site Aiken, SC 29808 SRNS-RP-2013-00005 Savannah River Site Ten Year Site Plan SRNS-RP-2013-00005 May 2013 DISCLAIMER This report was prepared by Savannah River Nuclear Solutions LLC (SRNS) for the United States Department of Energy under Contract No. DE-AC09-08SR22470 and is an account of work performed under that contract. Reference herein to any specific commercial product, process or services by trademark, name, manufacturer, or otherwise does not necessarily constitute or imply endorsement,

15

XRY{*?C**kL,x*SGH]??*?*COLyc**? (rP??*0Ge ...  

Science Conference Proceedings (OSTI)

XRY{*?C**kL,x*SGH]??*?*COLyc**? (rP??*0Ge

2012-10-23T23:59:59.000Z

16

Weak interaction rates for Kr and Sr waiting-point nuclei under rp-process conditions  

E-Print Network (OSTI)

Weak interaction rates are studied in neutron deficient Kr and Sr waiting-point isotopes in ranges of densities and temperatures relevant for the rp-process. The nuclear structure is described within a microscopic model (deformed QRPA) that reproduces not only the half-lives but also the Gamow-Teller strength distributions recently measured. The various sensitivities of the decay rates to both density and temperature are discussed. Continuum electron capture is shown to contribute significantly to the weak rates at rp-process conditions.

P. Sarriguren

2009-10-06T23:59:59.000Z

17

346 2010 ASHRAE This paper is based on findings resulting from ASHRAE Research Project RP-1299.  

E-Print Network (OSTI)

346 ©2010 ASHRAE This paper is based on findings resulting from ASHRAE Research Project RP-1299 (Minimum Efficiency Reporting Value, as defined by ASHRAE Standard 52.2-2007) typically have a greaterD Atila Novoselac, PhD Student Member ASHRAE Member ASHRAE Member ASHRAE Brent Stephens is a graduate

Siegel, Jeffrey

18

RiPed_By_ILookImager*p* #e?**??i /ft*rp-A,dST?L ...  

Science Conference Proceedings (OSTI)

RiPed_By_ILookImager*p*?#e?**??i /ft*rp-A,dST?L*6?ɢ??O? 42^*a ? ????l*ex?fA7???*?4TE?u\\??X ...

2005-01-09T23:59:59.000Z

19

Progress in Retinal and Eye Research 22 (2003) 607655 Neural remodeling in retinal degeneration  

E-Print Network (OSTI)

, Department of Ophthalmology, University of Utah School of Medicine, 50 N Medical Center, Salt Lake City, UT Accepted 31 March 2003 Abstract Mammalian retinal degenerations initiated by gene defects in rods, cones in the mammalian retina generally progress through three phases. Phase 1 initiates with expression of a primary

Marc, Robert E.

20

Retinal vessel segmentation using multiwavelet kernels and multiscale hierarchical decomposition  

Science Conference Proceedings (OSTI)

We propose a comprehensive method for segmenting the retinal vasculature in fundus camera images. Our method does not require preprocessing and training and can therefore be used directly on different images sets. We enhance the vessels using matched ... Keywords: Matched filter, Multiscale hierarchical decomposition, Multiwavelet, Retinal images, Segmentation, Vessel detection

Yangfan Wang; Guangrong Ji; Ping Lin; Emanuele Trucco

2013-08-01T23:59:59.000Z

Note: This page contains sample records for the topic "retinitis pigmentosa rp" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


21

Precise measurement of the {sup 64}Ge mass and its effect on the rp process  

SciTech Connect

The Canadian Penning Trap mass spectrometer has been used to determine the mass excesses of {sup 64}Ge and {sup 64}Ga as -54344(30) keV and -58832.5(39) keV, respectively. Under typical conditions used for modeling x-ray bursts, {sup 64}Ge is confirmed as a waiting-point nuclide and can contribute up to 35.5 s to the timescale of the rp process at a peak x-ray burst temperature of 1.5 GK.

Clark, J. A. [Wright Nuclear Structure Laboratory, Yale University, New Haven, Connecticut 06520 (United States); Department of Physics and Astronomy, University of Manitoba, Winnipeg, Manitoba R3T 2N2 (Canada); Physics Division, Argonne National Laboratory, Argonne, Illinois 60439 (United States); Sharma, K. S. [Department of Physics and Astronomy, University of Manitoba, Winnipeg, Manitoba R3T 2N2 (Canada); Savard, G. [Physics Division, Argonne National Laboratory, Argonne, Illinois 60439 (United States); Department of Physics, University of Chicago, Chicago, Illinois 60637 (United States); Levand, A. F.; Zhou, Z.; Seweryniak, D.; Trimble, W. [Physics Division, Argonne National Laboratory, Argonne, Illinois 60439 (United States); Wang, J. C. [Department of Physics and Astronomy, University of Manitoba, Winnipeg, Manitoba R3T 2N2 (Canada); Physics Division, Argonne National Laboratory, Argonne, Illinois 60439 (United States); Blank, B. [Physics Division, Argonne National Laboratory, Argonne, Illinois 60439 (United States); Centre d'Etudes Nucleaires de Bordeaux-Gradignan, F-33175 Gradignan Cedex (France); Buchinger, F.; Crawford, J. E.; Gulick, S.; Lee, J. K. P. [Department of Physics, McGill University, Montreal, Quebec H3A 2T8 (Canada)

2007-03-15T23:59:59.000Z

22

Savannah River Site Land Use Plan - May, 2013 i SRNS-RP-2013-00162  

NLE Websites -- All DOE Office Websites (Extended Search)

Savannah River Site Land Use Plan - May, 2013 i Savannah River Site Land Use Plan - May, 2013 i SRNS-RP-2013-00162 Savannah River Site Land Use Plan - May, 2013 i Table of Contents 1.0 - Purpose p1 2.0 - Executive Summary p1 3.0 - SRS Land Use Overview p5 Assumptions Current Land Use Leases, Transfers and Other Land Use Actions Future Land Use Land Use Issues 4.0 - Land Use Planning and Control for Existing Missions p13 Cleanup, Production and Support Missions Natural and Cultural Resource Management 5.0 - Process for Future Land Use Changes p15 Introduction Process Overview Process Description 6.0 - Summary p19 7.0 - References p20 8.0 - Acronyms p21 Savannah River Site Land Use Plan - May, 2013 i

23

Active multispectral illumination and image fusion for retinal microsurgery  

Science Conference Proceedings (OSTI)

It has been shown that white light exposure during retinal microsurgeries is detrimental to patients. To address this problem, we present a novel device and image processing tool, which can be used to significantly reduce the amount of phototoxicity ...

Raphael Sznitman; Seth Billings; Diego Rother; Daniel Mirota; Yi Yang; Jim Handa; Peter Gehlbach; Jin U. Kang; Gregory D. Hager; Russell Taylor

2010-06-01T23:59:59.000Z

24

Retinal prosthesis LLNL helped develop is approved by the FDA  

NLE Websites -- All DOE Office Websites (Extended Search)

6 For immediate release: 02152013 | NR-13-02-06 Retinal prosthesis LLNL helped develop is approved by the FDA Donald B Johnston, LLNL, (925) 423-4902, johnston19@llnl.gov...

25

Analysis of the RPE sheet in the rd10 retinal degeneration model  

SciTech Connect

The normal RPE sheet in the C57Bl/6J mouse is subclassified into two major tiling patterns: A regular generally hexagonal array covering most of the surface and a 'soft network' near the ciliary body made of irregularly shaped cells. Physics models predict these two patterns based on contractility and elasticity of the RPE cell, and strength of cellular adhesion between cells. We hypothesized and identified major changes in RPE regular hexagonal tiling pattern in rdl0 compared to C57BL/6J mice. RPE sheet damage was extensive but occurred in rd10 later than expected, after most retinal degeneration. RPE sheet changes occur in zones with a bullseye pattern. In the posterior zone around the optic nerve RPE cells take on larger irregular and varied shapes to form an intact monolayer. In mid periphery, there is a higher than normal density of cells that progress into involuted layers of RPE under the retina. The periphery remains mostly normal until late stages of degeneration. The number of neighboring cells varies widely depending on zone and progression. RPE morphology continues to deteriorate long after the photoreceptors have degenerated. The RPE cells are bystanders to the rd10 degeneration within photo receptors, and the collateral damage to the RPE sheet resembles stimulation of migration or chemotaxis. Quantitative measures of the tiling patterns and histopathology detected here, scripted in a pipeline written in Perl and Cell Profiler (an open source Matlab plugin), are directly applicable to RPE sheet images from noninvasive fundus autofluorescence (FAF), adaptive optics confocal scanning laser ophthalmoscope (AO-cSLO), and spectral domain optical coherence tomography (SD-OCT) of patients with early stage AMD or RP.

Jiang, Yi [Los Alamos National Laboratory

2011-01-04T23:59:59.000Z

26

Numerical Simulations of the Island-Induced Circulations over the Island of Hawaii during HaRP  

Science Conference Proceedings (OSTI)

The fifth-generation Pennsylvania State UniversityNCAR Mesoscale Model (MM5)/land surface model (LSM) is used to simulate the diurnal island-scale circulations over the island of Hawaii during the Hawaiian Rainband Project (HaRP, 11 July24 ...

Yang Yang; Yi-Leng Chen; Francis M. Fujioka

2005-12-01T23:59:59.000Z

27

End-point of the rp process and periodic gravitational wave emission  

E-Print Network (OSTI)

The general end-point of the rp process in rapidly accreting neutron stars is believed to be a surface distribution of matter whose nuclear composition may depend on position. Its evolution during compression beyond the neutron-drip threshold density is determined by the presence of nuclear formation enthalpy minima at the proton closed shells. At threshold, a sequence of weak interactions with capture or emission of neutron pairs rapidly transform nuclei to the most accessible proton closed shell. Therefore, angular asymmetries in nuclear composition present in accreted matter at neutron drip are preserved during further compression to higher densities provided transition rates between closed shells are negligible. Although it has been confirmed that this condition is satisfied for predicted internal temperatures and for the formation enthalpy distribution used in this work, it would not be so if the true enthalpy differences between maxima and minima in the distribution were a factor of two smaller. For this reason, it does not appear possible to assert with any confidence that position-dependent surface composition can lead to significant angle-dependence of the equation of state and to potentially observable gravitational radiation. The effect of non-radial internal temperature gradients on angle-dependency of the equation of state is also not quantifiable.

P. B. Jones

2005-02-09T23:59:59.000Z

28

Penning trap mass measurements on (99-109)$Cd with ISOLTRAP and implications on the rp process  

E-Print Network (OSTI)

Penning trap mass measurements on neutron-deficient Cd isotopes (99-109)Cd have been performed with the ISOLTRAP mass spectrometer at ISOLDE/CERN, all with relative mass uncertainties below 3*10^8. A new mass evaluation has been performed. The mass of 99Cd has been determined for the first time which extends the region of accurately known mass values towards the doubly magic nucleus 100Sn. The implication of the results on the reaction path of the rp process in stellar X-ray bursts is discussed. In particular, the uncertainty of the abundance and the overproduction created by the rp-process for the mass A = 99 is demonstrated by reducing the uncertainty of the proton-separation energy of 100In Sp(100In) by a factor of 2.5.

M. Breitenfeldt; G. Audi; D. Beck; K. Blaum; S. George; F. Herfurth; A. Herlert; A. Kellerbauer; H. -J. Kluge; M. Kowalska; D. Lunney; S. Naimi; D. Neidherr; H. Schatz; S. Schwarz; L. Schweikhard

2009-08-18T23:59:59.000Z

29

Byland's artificial retina story  

NLE Websites -- All DOE Office Websites (Extended Search)

Vision Quest Pioneer: Artificial Retina Recipient Sees Brighter Future Vision Quest Pioneer: Artificial Retina Recipient Sees Brighter Future Byland and Humayun Terry Byland and Dr. Mark Humayun at a 2006 Council for Competitiveness event. When Terry Byland began having trouble seeing in the dim light of dark restaurants and nightclubs, he wasn't overly concerned. Soon after, however, the problem began to affect his night driving. A year later, he went to an ophthalmologist to have his eyes checked. He wasn't prepared for the grave diagnosis: Retinitis pigmentosa (RP). "What's going to happen to me?" Byland asked his doctor, who told him that eventually he could go blind. RP is a group of relatively rare inherited eye diseases that attack the photoreceptor cells in the retina, affecting about 1 in 4,000 people. Symptoms begin with night blindness, generally progressing to tunnel vision

30

Artificial Retina Implant Eligibility  

NLE Websites -- All DOE Office Websites (Extended Search)

to Participate to Participate February 14, 2013: BREAKING NEWS FDA Approves Argus II After more than 20 years of research and development, Second Sight Medical Products, Inc., has announced that it's Argus® II Retinal Prosthesis System ("Argus II") has received U.S. market approval from the Food and Drug Administration (FDA) to treat individuals with late stage retinitis pigmentosa (RP). This announcement followed receipt of the European approval in 2011, and a unanimous recommendation by the FDA's Ophthalmic Devices Advisory Panel in September 2012 that this revolutionary product be made available to treat this patient population in the U.S. With approval from the FDA, the Argus II is slated to be available later in 2013 in clinical centers across the country. Second Sight will be actively adding sites to make the therapy more readily available and encourages interested facilities and patients to contact them.

31

In-vivo imaging of the photoreceptor mosaic in retinal dystrophies and correlations with visual function  

SciTech Connect

To relate in-vivo microscopic retinal changes to visual function assessed with clinical tests in patients with various forms of retinal dystrophies. The UC Davis Adaptive Optics (AO) Fundus Camera was used to acquire in-vivo retinal images at the cellular level. Visual function tests, consisting of visual field analysis, multifocal electroretinography (mfERG), contrast sensitivity and color vision measures, were performed on all subjects. Five patients with different forms of retinal dystrophies and three control subjects were recruited. Cone densities were quantified for all retinal images. In all images of diseased retinas, there were extensive areas of dark space between groups of photoreceptors, where no cone photoreceptors were evident. These irregular features were not seen in healthy retinas, but were characteristic features in fundi with retinal dystrophies. There was a correlation between functional vision loss and the extent to which the irregularities occurred in retinal images. Cone densities were found to decrease with an associated decrease in retinal function. AO fundus photography is a reliable technique for assessing and quantifying the changes in the photoreceptor layer as disease progresses. Furthermore, this technique can be useful in cases where visual function tests give borderline or ambiguous results, as it allows visualization of individual photoreceptors.

Choi, S; Doble, N; Hardy, J; Jones, S; Keltner, J; Olivier, S; Werner, J S

2005-10-26T23:59:59.000Z

32

An approach to localize the retinal blood vessels using bit planes and centerline detection  

Science Conference Proceedings (OSTI)

The change in morphology, diameter, branching pattern or tortuosity of retinal blood vessels is an important indicator of various clinical disorders of the eye and the body. This paper reports an automated method for segmentation of blood vessels in ... Keywords: Bit plane slicing, Blood vessel segmentation, First order derivative of Gaussian, Image segmentation, Mathematical morphology, Medical imaging, Retinal image, Ocular fundus

M. M. Fraz; S. A. Barman; P. Remagnino; A. Hoppe; A. Basit; B. Uyyanonvara; A. R. Rudnicka; C. G. Owen

2012-11-01T23:59:59.000Z

33

Tri-functional cannula for retinal endovascular surgery  

DOE Patents (OSTI)

A tri-functional cannula combines the functions of tissue Plasminogen Activator (tPA) solution delivery, illumination and venous pressure measurement. The cannula utilizes a tapered hollow-core optical fiber having an inlet for tPA solution, an attached fiber optic splitter configured to receive illumination light from an optical source such and a LED. A window in the cannula transmits the light to and from a central retinal vein. The return light is coupled to an optical detector to measure the pressure within the vein and determine whether an occlusion has been removed.

Weiss, Jonathan D. (Albuquerque, NM)

2010-07-27T23:59:59.000Z

34

Textureless Macula Swelling Detection with Multiple Retinal Fundus Images  

SciTech Connect

Retinal fundus images acquired with non-mydriatic digital fundus cameras are a versatile tool for the diagnosis of various retinal diseases. Because of the ease of use of newer camera models and their relatively low cost, these cameras can be employed by operators with limited training for telemedicine or Point-of-Care applications. We propose a novel technique that uses uncalibrated multiple-view fundus images to analyse the swelling of the macula. This innovation enables the detection and quantitative measurement of swollen areas by remote ophthalmologists. This capability is not available with a single image and prone to error with stereo fundus cameras. We also present automatic algorithms to measure features from the reconstructed image which are useful in Point-of-Care automated diagnosis of early macular edema, e.g., before the appearance of exudation. The technique presented is divided into three parts: first, a preprocessing technique simultaneously enhances the dark microstructures of the macula and equalises the image; second, all available views are registered using non-morphological sparse features; finally, a dense pyramidal optical flow is calculated for all the images and statistically combined to build a naiveheight- map of the macula. Results are presented on three sets of synthetic images and two sets of real world images. These preliminary tests show the ability to infer a minimum swelling of 300 microns and to correlate the reconstruction with the swollen location.

Giancardo, Luca [ORNL; Meriaudeau, Fabrice [ORNL; Karnowski, Thomas Paul [ORNL; Tobin Jr, Kenneth William [ORNL; Grisan, Enrico [University of Padua, Padua, Italy; Favaro, Paolo [Heriot-Watt University, Edinburgh; Ruggeri, Alfredo [University of Padua, Padua, Italy; Chaum, Edward [University of Tennessee, Knoxville (UTK)

2010-01-01T23:59:59.000Z

35

Clustering in the 1.2 Jy IRAS Galaxy Redshift Survey II: Redshift Distortions and ?(r_p,?)  

E-Print Network (OSTI)

We examine the effect of redshift space distortions on the galaxy two-point correlation function $\\xi(r_p,\\pi)$ as a function of separations parallel ($r_p$) and perpendicular ($\\pi$) to the line of sight. We find that the relative velocity dispersion of pairs of IRAS galaxies is $\\sigma(r)= 317^{+40}_{-49}$ \\kms at $r=1 \\mpc$, consistent with previous estimates derived from optically selected galaxy catalogues. Unfortunately, the use of this result to estimate $\\Omega$ via the Cosmic Virial Theorem is thwarted by large systematic uncertainties. We also fit for the mean relative streaming velocity of pairs, $v_{12}(r)$, which describes the growth of fluctuations on both linear and nonlinear scales. We find that $v_{12}(r) = 167^{+99}_{-67}$ \\kms at $r=4$\\mpc, so that on average, approximately half the Hubble expansion velocity of pairs at this separation is canceled by infall. At $r=10$\\mpc, the amplitude of the streaming is lower and $v_{12}(r) = 109^{+64}_{-47} \\kms$. Linear perturbation theory then implies that $\\Omega^{0.6}/b =0.45^{+0.27}_{-0.18}$ on scales $\\sim 10-15 \\mpc$. The amplitude of $v_{12}(r)$ is sensitive to the assumed shape of $\\sigma(r)$; if the latter deviates substantially from a virialized form on small scale, our best fit amplitude of $v_{12}(r)$ can deviate by a factor of two.

Karl B Fisher; Marc Davis; Michael A Strauss; Amos Yahil; John P Huchra

1993-08-09T23:59:59.000Z

36

Controllable stimulation of retinal rod cells using single photons  

E-Print Network (OSTI)

New tools and approaches of quantum optics offer a unique opportunity to generate light pulses carrying a precise number of photons (1). Accurate control over the light pulses helps to improve the characterization of photo-induced processes in biological systems (2). Here, we present a design of a specialised light source which provides exactly one photon at a time, and it is interfaced with retinal rod cells of Xenopus laevis toads. We give an independent proof for the single photon sensitivity of rod cells and measure single photon responses of individual cells. We determined their quantum efficiencies without the use of any pre-calibrated detectors (3-5), and obtained the value of (29+-4.7)%. Our approach provides the path for future studies and applications of quantum properties of light in phototransduction, vision, and photosynthesis (6-9).

Nam Mai Phan; Mei Fun Cheng; Dmitri A. Bessarab; Leonid A. Krivitsky

2013-08-03T23:59:59.000Z

37

Method and system for the diagnosis of disease using retinal image content and an archive of diagnosed human patient data  

DOE Patents (OSTI)

A method for diagnosing diseases having retinal manifestations including retinal pathologies includes the steps of providing a CBIR system including an archive of stored digital retinal photography images and diagnosed patient data corresponding to the retinal photography images, the stored images each indexed in a CBIR database using a plurality of feature vectors, the feature vectors corresponding to distinct descriptive characteristics of the stored images. A query image of the retina of a patient is obtained. Using image processing, regions or structures in the query image are identified. The regions or structures are then described using the plurality of feature vectors. At least one relevant stored image from the archive based on similarity to the regions or structures is retrieved, and an eye disease or a disease having retinal manifestations in the patient is diagnosed based on the diagnosed patient data associated with the relevant stored image(s).

Tobin, Kenneth W; Karnowski, Thomas P; Chaum, Edward

2013-08-06T23:59:59.000Z

38

Supernormal vision, high-resolution retinal imaging, multiphoton imaging and nanosurgery of the cornea: a review  

Science Conference Proceedings (OSTI)

Wavelength-corrected, adaptive optics and their relevance for diagnostic procedures of the human retina are considered. First, it is shown that the compensation of errors of the dioptric apparatus of the eye allows sharp and high-contrast images of retinal ... Keywords: aberrometry, adaptive optics, femtosecond laser, nanoresolution, picosecond laser, superresolution, supervision, wave-front correction

Franz Fankhauser; Peter F. Niederer; Sylwia Kwasniewska; Eugen van der Zypen

2004-12-01T23:59:59.000Z

39

Lithium chloride protects retinal neurocytes from nutrient deprivation by promoting DNA non-homologous end-joining  

SciTech Connect

Lithium chloride is a therapeutic agent for treatment of bipolar affective disorders. Increasing numbers of studies have indicated that lithium has neuroprotective effects. However, the molecular mechanisms underlying the actions of lithium have not been fully elucidated. This study aimed to investigate whether lithium chloride produces neuroprotective function by improving DNA repair pathway in retinal neurocyte. In vitro, the primary cultured retinal neurocytes (85.7% are MAP-2 positive cells) were treated with lithium chloride, then cultured with serum-free media to simulate the nutrient deprived state resulting from ischemic insult. The neurite outgrowth of the cultured cells increased significantly in a dose-dependent manner when exposed to different levels of lithium chloride. Genomic DNA electrophoresis demonstrated greater DNA integrity of retinal neurocytes when treated with lithium chloride as compared to the control. Moreover, mRNA and protein levels of Ligase IV (involved in DNA non-homologous end-joining (NHEJ) pathway) in retinal neurocytes increased with lithium chloride. The end joining activity assay was performed to determine the role of lithium on NHEJ in the presence of extract from retinal neurocytes. The rejoining levels in retinal neurocytes treated with lithium were significantly increased as compared to the control. Furthermore, XRCC4, the Ligase IV partner, and the transcriptional factor, CREB and CTCF, were up-regulated in retinal cells after treating with 1.0 mM lithium chloride. Therefore, our data suggest that lithium chloride protects the retinal neural cells from nutrient deprivation in vitro, which may be similar to the mechanism of cell death in glaucoma. The improvement in DNA repair pathway involving in Ligase IV might have an important role in lithium neuroprotection. This study provides new insights into the neural protective mechanisms of lithium chloride.

Zhuang Jing; Li Fan; Liu Xuan; Liu Zhiping; Lin Jianxian [State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 54 S Xianlie Road, Guangzhou, Guangdong 510060 (China); Ge Yihong [Department of Stomatology, the Southern Medical University (China); Kaminski, Joseph M. [National Institute of Allergy and Infectious Diseases, Division of Allergy, Immunology, and Transplantation, University of South Alabama (United States); Summers, James Bradley [Department of Radiology, University of South Alabama (United States); Wang Zhichong [State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 54 S Xianlie Road, Guangzhou, Guangdong 510060 (China); Ge Jian [State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 54 S Xianlie Road, Guangzhou, Guangdong 510060 (China)], E-mail: gejian@mail.sysu.edu.cn; Yu Keming [State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 54 S Xianlie Road, Guangzhou, Guangdong 510060 (China)], E-mail: yukeming@mail.sysu.edu.cn

2009-03-13T23:59:59.000Z

40

AN EXPERIMENTAL STUDY OF RETINAL BURNS: PART I. THE IRRADIANCE THRESHOLDS FOR CHORIO-RETINAL LESIONS. PART II. ENTOPTIC SCATTER AS A FUNCTION OF WAVE LENGTH  

SciTech Connect

Using a high intensity light source to produce chorioretinal lesions in the eyes of rabbits, cats, and guinea pigs, the authors determined, at different levels of retinal irradiance, the exposure time which produced an ophthalmoscopically visible lesion. It was found that, at irradiance levels greater than 2 cal/cm/sup 2/sec, a radiant exposure of 1.0 cal/cm/sup 2/ produced a threshold lesion. At irradiance levels less than 0.7 cal/cm/sup 2//sec, lesions could not be produced at any exposure time through ten seconds. Histological data on the nature of the legions and course of healing are presented and discussed. (auth)

Demott, D.W.; Davis, T.P.

1959-05-11T23:59:59.000Z

Note: This page contains sample records for the topic "retinitis pigmentosa rp" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


41

Deuterium NMR Structure of Retinal in the Ground State of Rhodopsin Gilmar F. J. Salgado, Andrey V. Struts, Katsunori Tanaka,| Naoko Fujioka,|, Koji Nakanishi,| and  

E-Print Network (OSTI)

Deuterium NMR Structure of Retinal in the Ground State of Rhodopsin Gilmar F. J. Salgado, Andrey V-directed deuterium (2H) NMR spectroscopy was used to investigate the structure of retinal within the binding pocket of 2H NMR spectra were fit to a theoretical line shape analysis [Nevzorov, A. A., Moltke, S., Heyn, M

Brown, Michael F.

42

High-resolution retinal imaging using adaptive optics and Fourier-domain optical coherence tomography  

DOE Patents (OSTI)

This invention permits retinal images to be acquired at high speed and with unprecedented resolution in three dimensions (4.times.4.times.6 .mu.m). The instrument achieves high lateral resolution by using adaptive optics to correct optical aberrations of the human eye in real time. High axial resolution and high speed are made possible by the use of Fourier-domain optical coherence tomography. Using this system, we have demonstrated the ability to image microscopic blood vessels and the cone photoreceptor mosaic.

Olivier, Scot S. (Livermore, CA); Werner, John S. (Davis, CA); Zawadzki, Robert J. (Sacramento, CA); Laut, Sophie P. (Pasedena, CA); Jones, Steven M. (Livermore, CA)

2010-09-07T23:59:59.000Z

43

rl038rp6.PDF  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

HANFORD SITE HANFORD SITE DURING THE AUDIT OF THE DEPARTMENT OF ENERGY'S CONSOLIDATED FISCAL YEAR 1999 FINANCIAL STATEMENTS Report Number: WR-FS-00-01 Western Regional Audit Office Date of Issue: March 15, 2000 Albuquerque, New Mexico 87185 REPORT ON MATTERS IDENTIFIED AT THE HANFORD SITE DURING THE AUDIT OF THE DEPARTMENT OF ENERGY'S CONSOLIDATED FISCAL YEAR 1999 FINANCIAL STATEMENTS TABLE OF CONTENTS Page SUMMARY... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ..... . 1 PART I - APPROACH AND OVERVIEW... ... ... ... ... ... ... ... ... ... ... ... ..... ... ... . 2 Introduction... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ..... ... .. 2 Scope and Methodology... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ..... ... ... ... 2 Observations... ... ... ... ... ... ... ... ... ...

44

if020rp6.PDF  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

IDAHO OPERATIONS OFFICE IDAHO OPERATIONS OFFICE DURING THE AUDIT OF THE DEPARTMENT OF ENERGY'S CONSOLIDATED FISCAL YEAR 1999 FINANCIAL STATEMENTS Report Number: WR-FS-00-02 Western Regional Audit Office Date of Issue: March 20, 2000 Albuquerque, New Mexico 87185 REPORT ON MATTERS IDENTIFIED AT THE IDAHO OPERATIONS OFFICE DURING THE AUDIT OF THE DEPARTMENT OF ENERGY'S CONSOLIDATED FISCAL YEAR 1999 FINANCIAL STATEMENTS TABLE OF CONTENTS Page SUMMARY... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ..... ... ... ... 1 PART I - APPROACH AND OVERVIEW... ... ... ... ... ... .... ... ... ... ... ... ... ... ... 2 Introduction... ... ... ... ... ... ... ... ... ... ... ... ... ... ... .... ... ... ... ... ... ... ... . 2 Scope and Methodology... ... ... ... ... ... ... ... .... ... ... ... ... ... ... ... ... ... .. 2 Observations...

45

DOE FINAL TECHNICAL REPORT RP  

DOE Green Energy (OSTI)

The City of Georgetown Utility Systems (GUS) patnered with the private sector, the American Public Power Association (APPA) and Southwestern University to design, construct, test and monitor a solar co-generation system directly connected to the GUS electric distribution system. This report consists of the Primary Technical Report and 3 attachments.

RUSS PETERMAN

2012-01-01T23:59:59.000Z

46

US CMS- RP PMG US CMS- RP PMG US CMS- RP PMG  

NLE Websites -- All DOE Office Websites (Extended Search)

which was substantially at variance with the existing plan. * Given the inelastic salary base, we must insure that we do not overspend this new FY04 and FY05 guidance. This...

47

Retinal instrument  

DOE Patents (OSTI)

In one embodiment, the present invention provides a method of removing scar tissue from an eye that includes inserting a device including an array of micro-rods into an eye, wherein at least one glass micro-rod of the array of glass micro-rods includes a sharp feature; contacting a scar tissue with the array of micro-rods; and removing the array of micro-rods and the scar tissue from the eye. In another embodiment, the present invention provides a medical device for engaging a tissue including and an array of glass micro-rods, wherein at least one glass micro-rod of the array of glass micro-rods includes a sharp feature opposite a base of the array of glass micro-rods that is connected to the cannula, wherein the sharp feature of the at least one micro-rod is angled from a plane that is normal to a face of the base of the array of glass micro-rods.

Britton, Charles L; D& #x27; Urso, Brian R; Chaum, Edward; Simpson, John T; Baba, Justin S; Ericson, M. Nance; Warmack, Robert J

2013-04-23T23:59:59.000Z

48

Induction of dark-adaptive retinomotor movement (cell elongation) in teleost retinal cones by cyclic AMP  

E-Print Network (OSTI)

ABSTRACT In the teleost retina, the photoreceptors and retinal pigment epithelium (RPE) undergo extensive movements (called retinomotor movements) in response to changes in light conditions and to an endogenous circadian rhythm. Photoreceptor movements serve to reposition the light-receptive outer segments and are effected by changes in inner segment length. Melanin granule movements within the RPE cells provide a movable melanin screen for rod outer segments. In the dark (night), cones elongate, rods contract, and pigment granules aggregate to the base of the RPE cell; in the light (day), these movements are reversed. We report here that treatments that elevate cytoplasmic cyclic adenosine 3',5'-monophosphate (CAMP) provoke retinomotor movements characteristic of nighttime dark adapation, even in bright light at midday. To illustrate this response, we present a quantitative description of the effects of cyclic nucleotides on cone length in the green sunfish, Lepomis cyanellus. Cone elongation is induced when light-adapted retinas are exposed to exogenous CAMP analogues accompanied by phosphodiesterase (PDE) inhibitors (either by intraocular injection or in retinal organ culture). Cone movement is not affected by cyclic GMP analogues. Dose-response studies indicate that the extent, but not the rate, of cone elongation is proportional to the concentration of exogenous CAMP and analogue presented. As has been reported for other species, we find that levels of CAMP are significantly higher in dark- than in light-adapted green sunfish retinas. On the basis of these observations, we suggest that CAMP plays a role in the light and circadian regulation of teleost cone length.

Adenosine ' -monophosphate; Beth Burnside; Michael Evans; R Theodore Fletcher; G J Chader

1982-01-01T23:59:59.000Z

49

Dietary Fats and Risk of Chronic DiseaseChapter 17 Docosahexaenoic Acid Intake and Lipid peroxidation in Retinal Membranes of Rats  

Science Conference Proceedings (OSTI)

Dietary Fats and Risk of Chronic Disease Chapter 17 Docosahexaenoic Acid Intake and Lipid peroxidation in Retinal Membranes of Rats Health Nutrition Biochemistry eChapters Health - Nutrition - Biochemistry Press Download

50

Concurrent expression of heme oxygenase-1 and p53 in human retinal pigment epithelial cell line  

SciTech Connect

Heme oxygenase-1 (HO-1) is a stress-responsive protein that is known to regulate cellular functions such as cell proliferation, inflammation, and apoptosis. Here, we investigated the effects of HO activity on the expression of p53 in the human retinal pigment epithelium (RPE) cell line ARPE-19. Cobalt protoporphyrin (CoPP) induced the expression of both HO-1 and p53 without significant toxicity to the cells. In addition, the blockage of HO activity with the iron chelator DFO or with HO-1 siRNA inhibited the CoPP-induced expression of p53. Similarly, zinc protoporphyrin (ZnPP), an inhibitor of HO, suppressed p53 expression in ARPE-19 cells, although ZnPP increased the level of HO-1 protein while inhibiting HO activity. Also, CoPP-induced p53 expression was not affected by the formation of reactive oxygen species (ROS). Based on these results, we conclude that HO activity is involved in the regulation of p53 expression in a ROS-independent mechanism, and also suggest that the expression of p53 in ARPE-19 cells is associated with heme metabolites such as biliverdin/bilirubin, carbon monoxide, and iron produced by the activity of HO.

Lee, Sang Yull [Department of Biochemistry, Pusan National University School of Medicine, Busan 602-739 (Korea, Republic of); Jo, Hong Jae [Department of General Surgery, Pusan National University School of Medicine, Busan 602-739 (Korea, Republic of); Kim, Kang Mi; Song, Ju Dong [Department of Microbiology and Immunology, Pusan National University School of Medicine, 1-10 Ami-Dong, Seo-Gu, Busan 602-739 (Korea, Republic of); Chung, Hun Taeg [Department of Microbiology and Immunology, Wonkwang University School of Medicine, Iksan, Chonbuk 570-749 (Korea, Republic of); Park, Young Chul [Department of Microbiology and Immunology, Pusan National University School of Medicine, 1-10 Ami-Dong, Seo-Gu, Busan 602-739 (Korea, Republic of)], E-mail: ycpark@pusan.ac.kr

2008-01-25T23:59:59.000Z

51

Networking RP @ DISI Fabrizio Granelli, Lab Coordinator  

E-Print Network (OSTI)

S and resource management Wireless mesh networks: WiFi, WiMax Cellular: transmission, protocols and network and management Distributed signaling Overlay to network mapping and cooperation Research Topics: Protocol Design-Layering Performance Improvement in Wireless Networks Congestion Control GRID & Overlay Networks Design of Wireless

Granelli, Fabrizio

52

DE-RP36-98GO  

NLE Websites -- All DOE Office Websites (Extended Search)

shall notify the Agency Contracting Officer fifteen (15) working days in advance of PV and ECM installation completion (or such other notification period as may be specified...

53

Survival of retinal pigment epithelium after exposure to prolonged oxidative injury: a detailed gene expression and cellular analysis. Invest Ophthalmol Vis Sci 45  

E-Print Network (OSTI)

PURPOSE. To detail, by DNA microarrays and cellular structure labeling, the in vitro responses of retinal pigment epithelial (RPE) cells to a nonlethal dose of the oxidant agent hydroquinone (HQ). METHODS. The viability of growth-quiescent ARPE-19 cells after treatment with HQ was measured by XTT conversion, 3 H-leucine incorporation, trypan blue exclusion, and the presence of DNA laddering. The effect of a nonlethal dose of HQ on the localization of apoptosis-induced factor (AIF) and phosphorylation of stress-activated kinase-2/p38 (SAPK2/p38) was detected by immunocytochemistry. Actin structures were visualized by phalloidin staining. Cell membrane blebbing was detected using GFP-membranelabeled RPE cells (ARPE-GFP-crRas). Changes in gene expression patterns of RPE cells within 48 hours of prolonged treatment with a nonlethal dose of HQ

Nataly Strunnikova; Connie Zhang; Diane Teichberg; Scott W. Cousins; Judit Baffi; Kevin G. Becker; Karl G. Csaky

2004-01-01T23:59:59.000Z

54

Microsoft Word - CSP_RP_PhaseI_051305.doc  

NLE Websites -- All DOE Office Websites (Extended Search)

*(2) Eagle Operating, Inc. Encore Acquisition Company Fischer Oil & Gas, Inc. Marathon Oil Company Occidental Petroleum Oxy Permian Ltd. Saskatchewan Industry and Resources...

55

Importance of Q-values in astrophysical rp-proces  

E-Print Network (OSTI)

The importance of measuring Q-values in rapid proton capture process has been investigated. The microscopic optical model, derived using a nucleon nucleon interaction and densities from relativistic mean field calculations, has been utilized to calculate the reaction rates. It has been observed that the Q-values involved in the reactions at waiting points at A = 60 and 64 are very important in determining the final abundance of the process. Some other Q-values also play a crucial role in the final abundance of nuclei near the end point of the process.

Chirashree Lahiri; G. Gangopadhyay

2013-05-27T23:59:59.000Z

56

MIT LFEE 2005-002 RP Prepared by:  

E-Print Network (OSTI)

*This work was submitted for Masters of Science Thesis and has been re-formatted here as a LFEE Report

Power Plants; Ram C. Sekar

2005-01-01T23:59:59.000Z

57

FDA Approves First Bionic Eye for the Blind | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

FDA Approves First Bionic Eye for the Blind FDA Approves First Bionic Eye for the Blind FDA Approves First Bionic Eye for the Blind February 14, 2013 - 1:06pm Addthis NEWS MEDIA CONTACT (202) 586-4940 WASHINGTON- The U.S. Department of Energy announced today that its support for a decade of revolutionary research has contributed to the creation of the first ever retinal prosthesis - or bionic eye - to be approved in the United States by the U.S. Food and Drug Administration for blind individuals with end-stage retinitis pigmentosa. "The development of the artificial retina is just one more example of the unique value of our National Laboratories and research universities," said Energy Secretary Steven Chu. "While no one can predict a breakthrough before it happens, the investments we're making in research

58

CHAPTER: In-Situ Characterization of Stimulating Microelectrode Arrays: Study of an Idealized Structure Based on Argus II Retinal implantsBOOK TITLE: Implantable Neural Prostheses 2: Techniques and Engineering Approaches, D.M. Zhou and E. Greenbaum, Eds., Springer, NY 2009  

SciTech Connect

The development of a retinal prosthesis for artificial sight includes a study of the factors affecting the structural and functional stability of chronically implanted microelectrode arrays. Although neuron depolarization and propagation of electrical signals have been studied for nearly a century, the use of multielectrode stimulation as a proposed therapy to treat blindness is a frontier area of modern ophthalmology research. Mapping and characterizing the topographic information contained in the electric field potentials and understanding how this information is transmitted and interpreted in the visual cortex is still very much a work in progress. In order to characterize the electrical field patterns generated by the device, an in vitro prototype that mimics several of the physical and chemical parameters of the in vivo visual implant device was fabricated. We carried out multiple electrical measurements in a model 'eye,' beginning with a single electrode, followed by a 9-electrode array structure, both idealized components based on the Argus II retinal implants. Correlating the information contained in the topographic features of the electric fields with psychophysical testing in patients may help reduce the time required for patients to convert the electrical patterns into graphic signals.

Greenbaum, Elias [ORNL; Sanders, Charlene A [ORNL; Kandagor, Vincent [ORNL

2010-01-01T23:59:59.000Z

59

JOURNAL OF RESEARCH IN PERSONALITY 31, 193221 (1997) ARTICLE NO. RP972175  

E-Print Network (OSTI)

to Infidelity in the First Year of Marriage David M. Buss and Todd K. Shackelford The University of Texas. Shackelford. Address correspondence and reprint requests to David M. Buss or Todd K. Shackelford@psy.utexas.edu or shackelford@psy.utexas.edu. 193 0092-6566/97 $25.00 Copyright © 1997 by Academic Press All rights

Pillow, Jonathan

60

Low-lying levels in Cu-57 and the rp process  

E-Print Network (OSTI)

The level scheme of Cu-57 is investigated via the H-1(Ni-58,Cu-57-gamma)2n reaction by using the recoil mass spectrometer MARS at the Texas AandM Cyclotron Institute. Three low-lying excited states are observed in Cu-57 at 1028 +/- 4, 1106 +/- 4, and 2398 +/- 10 keV. The results are compared with well known excited states of the mirror nucleus Ni-57. Th, measured excited states of Cu-57 allow recalculation of the astrophysical reaction rate for the stellar radiative proton capture reaction Ni-56(p,gamma)Cu-57.

Zhou, XG; Dejbakhsh, H.; Gagliardi, Carl A.; Jiang, J.; Trache, L.; Tribble, Robert E.

1996-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "retinitis pigmentosa rp" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


61

DE-RP36-98G010219 L.9 FALSE STATEMENTS Proposals  

NLE Websites -- All DOE Office Websites (Extended Search)

analysis, design and engineering of PV systems and energy efficiency measures, installation of PV systems and energy efficiency measures, operations and maintenance of...

62

-DECAY HALF-LIFE OF THE rp-PROCESS WAITING-POINT NUCLIDE 84  

E-Print Network (OSTI)

84 Mo By Joshua Bradshaw Stoker 84Mo is an even-even N = Z nucleus lying on the proton drip line to deduce half-lives and other properties of the decay required that the average time between implantations you for your insights and conversations to breakup many tense work days. My family certainly has

Mantica, Paul F.

63

Request for Proposal Number DE-RP36-98GO10337 for the Management...  

NLE Websites -- All DOE Office Websites (Extended Search)

b) n -- - -- limited rights data are as set forth in the Limited Rights Notice of paragraph (g) of this clause. (5) Restricted Computer Software, as used in this clause, means...

64

Baroclinic Energy Flux at the Hawaiian Ridge: Observations from the R/P FLIP  

Science Conference Proceedings (OSTI)

Estimates of baroclinic energy flux are made in the immediate Nearfield (SeptemberOctober 2002) and 450 km offshore (Farfield; OctoberNovember 2001) of the Kaena Ridge, an active barotropic-to-baroclinic conversion site. The flux estimates ...

Luc Rainville; Robert Pinkel

2006-06-01T23:59:59.000Z

65

CBFO:AMO:RP:GS:05-0217:UFC 5486.00 Department of Energy  

E-Print Network (OSTI)

Subject: Hanford Tank and K-Basin Wastes Dear Ms. Cotsworth: I am responding to your December 17, 2004 letter in which the Environmental Protection Agency (EPA) asked for information on the Hanford tank and K). The U.S. Department of Energy (DOE) believes the Hanford tank wastes and K-Basin wastes meet

66

Request for Proposal Number DE-RP36-98GO10337 for the Management...  

NLE Websites -- All DOE Office Websites (Extended Search)

Contractor, or the sale or other disposition of all or substantially all of the capital stock, business or assets of Contractor to any other person or party, or (ii) the...

67

A Coupled Airflow-and-Energy Simulation Program for Indoor Thermal Environment Studies (RP-927)  

E-Print Network (OSTI)

) Jelena Srebric* Qingyan Chen; Ph.D. Leon R. Glicksman; Ph.D. ASHRAE Student Member ASHRAE Member ASHRAE for thermal comfort (ASHRAE 1992). In an indoor space with radiative, convective, and hybrid heating-and-energy simulation program for indoor thermal environment studies," ASHRAE Transactions, 106(1), 465-476. #12

Chen, Qingyan "Yan"

68

BN-97-4-4 (RP-875) The Radiant Time Series Cooling  

E-Print Network (OSTI)

, Ph.D., P.E. Member ASHRAE Daniel E. Fisher, Ph.D. Member ASHRAE Curtis O. Pedersen, Ph.D. Fellow ASHRAE ABSTRACT Theradiant time series methodis a newmethodfor per- forming design cooling load, Inc. (www.ashrae.org). P

69

Request for Proposal Number DE-RP36-98GO10337 for the Management...  

NLE Websites -- All DOE Office Websites (Extended Search)

. . . . . . . . . . . . . . .. 40 LOBBYING RESTRICTION (ENERGY & WATER DEVELOPMENT APPROPRIATIONS ACT, 1998) (AL 97-10) . . . .. . . . . . . . . . . . . . . . . . . . . . .. . . ....

70

Request for Proposal Number DE-RP36-98GO10337 for the Management...  

NLE Websites -- All DOE Office Websites (Extended Search)

DIRECTIVES (This list may be modified from time to time through deletions or additions) DOE DIRECTIVES All DOE Directives can be found at the following Internet address: http:...

71

Request for Proposal Number DE-RP36-98GO10337 for the Management...  

NLE Websites -- All DOE Office Websites (Extended Search)

requirements imposed by the Contracting Officer pursuant to the Laws, Regulations, and DOE Directives clause of this contract. Nothing in this paragraph (a) is to be construed...

72

Request for Proposal Number DE-RP36-98GO10337 for the Management...  

NLE Websites -- All DOE Office Websites (Extended Search)

7. 952.227-13 PATENT RIGHTS-ACQUISITION BY THE GOVERNMENT. (SEP 1997) AND 970.5204-72 PATENT RIGHTS-PROFIT MAKING MANAGEMENT AND OPERATING CONTRACTORS (FEB 1995) (a) Definitions....

73

WSRC-RP-2003-00276 Department of Energy Office of Science and Technology  

E-Print Network (OSTI)

by trade name, trademark, manufacturer, or otherwise does not necessarily constitute or imply its the Department of Energy (DOE) Kansas City Plant (KCP) contain polychlorinated biphenyls (PCBs) resulting from the storm sewer are being implemented. DOE KCP requested an independent assessment of the historical

Hazen, Terry

74

Request for Proposal Number DE-RP36-98GO10337 for the Management...  

NLE Websites -- All DOE Office Websites (Extended Search)

on or before August 1 of each year. The Contractor shall also provide DOE a 1-Year Plan describing its proposed institutional initiatives and goals for NREL considering all...

75

Request for Proposal Number DE-RP36-98GO10337 for the Management...  

NLE Websites -- All DOE Office Websites (Extended Search)

in an approved budget Foreign travel is defined as any travel outside of Canada, Mexico, and the United States and its territories and possessions. (b) Request for approval...

76

Artificial Retina Implant Eligibility  

NLE Websites -- All DOE Office Websites (Extended Search)

CRADA Established October 14, 2004 CRADA Established October 14, 2004 A Joint Research Partnership Between the U.S. Department of Energy (DOE), DOE Laboratories, Universities, and a Private Company On October 14, 2004, the Department of Energy and Second Sight Medical Products, Inc. of Sylmar, California, held a press conference to announce the formal signing of a CRADA* for the Artificial Retina Project. This press conference included a speech by Energy Secretary Abraham, five minute video presentation, and multiple press releases. The press releases and video are listed below. Video A video explaining the artificial retina project and retinitis pigmentosa was shown during the press conference. This video is available on the video page. "See Artificial Retina Project Overview."

77

1  

NLE Websites -- All DOE Office Websites (Extended Search)

Lab team makes unique contributions to Lab team makes unique contributions to the first bionic eye June 27, 2013 As part of the multi-institutional Artificial Retina Project, Los Alamos researchers helped develop the first bionic eye. Recently approved by the U.S. Food and Drug Administration, the Argus II will help people blinded by the rare hereditary disease retinitis pigmentosa or seniors suffering from severe macular degeneration-diseases that destroy the light-sensing cell in the retina. Los Alamos scientists served as the Advanced Concepts team, focusing on fundamental issues and out-of the box ideas. Significance of the research The Argus II operates by using a miniature camera mounted in eyeglasses that captures images and wirelessly sends the information to a microprocessor (worn on a belt) that converts the data to an electronic signal. Pulses from an electrode

78

Background  

E-Print Network (OSTI)

Cyclic nucleotide-gated (CNG) channels are members of the superfamily of pore loop cation channels that are activated by the binding of cGMP or cAMP. The channels are important cellular switches which transduce changes in intracellular levels of cyclic nucleotides into changes of the membrane potential and the Ca 2+ concentration. CNG channels play a central role in the signal transduction pathways of vision and olfaction. We have studied the physiological significance of a particular member of the CNG channel family, CNGB1. The two splicing variants of CNGB1, termed CNGB1a and CNGB1b, assemble with CNGA1 and CNGA2/4 to form the native tetrameric CNG channels of rod photoreceptors and olfactory neurons, respectively. retinitis pigmentosa [1]. Using a combination of electrophysiologcal

Martin Biel; Stylianos Michalakis; Xiangang Zong; Elvir Becirovic

2009-01-01T23:59:59.000Z

79

About the Artificial Retina Project  

NLE Websites -- All DOE Office Websites (Extended Search)

Overview of the Overview of the Artificial Retina Project The DOE Artificial Retina Project was a multi-institutional collaborative effort to develop and implant a device containing an array of microelectrodes into the eyes of people blinded by retinal disease. The ultimate goal was to design a device to help restore limited vision that enables reading, unaided mobility, and facial recognition. The device is intended to bypass the damaged eye structure of those with retinitis pigmentosa and macular degeneration. These diseases destroy the light-sensing cells (photoreceptors, or rods and cones) in the retina, a multilayered membrane located at the back of the eye. For more information, see How the Artificial Retina Works. History The DOE project builds on the foundational work of its leader, Mark Humayun at the Doheny Eye Institute of the University of Southern California. In a breakthrough operation performed in 2002, a team led by Humayun successfully implanted the first device of its kind-an array containing 16 microelectrodes-into the eye of a patient who had been blind for more than 50 years. Since then, more than 30 additional volunteers around the world have had first- or second-generation (60-electrode) devices implanted. These devices enable patients to distinguish light from dark and localize large objects. For more information, read patient stories.

80

How the Artificial Retina Works  

NLE Websites -- All DOE Office Websites (Extended Search)

the Artificial Retina Works the Artificial Retina Works Artificial Retina Diagram Normal vision begins when light enters and moves through the eye to strike specialized photoreceptor (light-receiving) cells in the retina called rods and cones. These cells convert light signals to electric impulses that are sent to the optic nerve and the brain. Retinal diseases like age-related macular degeneration and retinitis pigmentosa destroy vision by annihilating these cells. With the artificial retina device, a miniature camera mounted in eyeglasses captures images and wirelessly sends the information to a microprocessor (worn on a belt) that converts the data to an electronic signal and transmits it to a receiver on the eye. The receiver sends the signals through a tiny, thin cable to the microelectrode array, stimulating it to emit pulses. The artificial retina device thus bypasses defunct photoreceptor cells and transmits electrical signals directly to the retina's remaining viable cells. The pulses travel to the optic nerve and, ultimately, to the brain, which perceives patterns of light and dark spots corresponding to the electrodes stimulated. Patients learn to interpret these visual patterns.

Note: This page contains sample records for the topic "retinitis pigmentosa rp" from the National Library of EnergyBeta (NLEBeta).
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they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


81

Applied Mathematical Sciences, Vol. 3, 2009, no. 54, 2703 -2706 The Limit of the Statistic R/P in Models  

E-Print Network (OSTI)

to predict that the peak of oil production in the U.S.A. would occur between 1965 and 1970. Oil produc- tion for the U.S.A actually peaked in 1970. In Hubbert's analysis the profile for oil production is approximated/P in Models of Oil Discovery and Production Dudley Stark School of Mathematical Sciences Queen Mary

Stark, Dudley

82

Evolution of the Subtropical Marine Boundary Layer: Comparison of Soundings over the Eastern Pacific from FIRE and HaRP  

Science Conference Proceedings (OSTI)

The mean time rates of change of temperature, total water mixing ratio and ozone along airflow trajectories in the lower troposphere over the eastern Pacific are inferred by comparing aircraft soundings from the First ISCCP Regional Experiment (...

I. R. Paluch; D. H. Lenschow; S. Siems; G. L. Kok; R. D. Schillawski; S. McKeen

1994-06-01T23:59:59.000Z

83

Exploring the retinal connectome James R. Anderson,1  

E-Print Network (OSTI)

Department of Ophthalmology, Moran Eye Center, University of Utah, Salt Lake City, UT; 2The Boulder and Imaging Institute, University of Utah, Salt Lake City, UT; 4Sorenson Media, Salt Lake City, UT; 5Department Electrical and Computer Engineering, University of Utah, Salt Lake City, UT Purpose: A connectome

Utah, University of

84

Molecular Mechanisms of a Retinal Cyclic Nucleotide-Gated Channel.  

E-Print Network (OSTI)

??Cyclic nucleotide-gated (CNG) channels mediate the transduction of light signals to electrical signals in vertebrate photoreceptors. These channels are non-selective for cations and open upon (more)

Martinez-Francois, Juan R

2009-01-01T23:59:59.000Z

85

Polarization and orientation of retinal ganglion cells in vivo  

E-Print Network (OSTI)

-coupled device (CCD) Hamamatsu Orca cameras and automated z-drive and fluorescence shutters. Acquisition of z-stacks and deconvolution were performed with Openlab soft- ware. For transmission electron microscopy, embryos were dis- sected rapidly and fixed for 4... /1/2 2006 Zolessi et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution...

Zolessi, Flavio R; Poggi, Lucia; Wilkinson, Christopher J; Chien, Chi-Bin; Harris, William A

2006-10-13T23:59:59.000Z

86

Retinal Instrument for Removing Scar Tissue from the Eye  

Surgeons currently peel it with an instrument that can result ... Brian R. DUrso, Edward Chaum, ... Measurement Science and Systems

87

Enhanced differentiation of retinal progenitor cells using microfabricated topographical cues  

E-Print Network (OSTI)

2004b; Meyer et al. 2006; Canola et al. 2007; Klassen et al.Br J Ophthalmol 90(12), K. Canola, B. Angenieux et al. ,

Steedman, Mark R.; Tao, Sarah L.; Klassen, Henry; Desai, Tejal A.

2010-01-01T23:59:59.000Z

88

EARLY REMODELING IN AN INDUCIBLE ANIMAL MODEL OF RETINAL DEGENERATION  

E-Print Network (OSTI)

fluoride membrane (MDI Membrane Technologies, Ambala, India). The blot was incubated at room temperature

Dhingra, Narender K.

89

Attempt to Identify Novel IFT Mutant through PCR Sequencing and Analysis of Chlamydomonas reinhardtii Flagellar Mutants  

E-Print Network (OSTI)

The flagella organelle is crucial to many different cells and organisms because it allows for sensation and movement throughout a matrix. The Intraflagellar Transport system (IFT) is of particular interest since it helps build and maintain the flagella through anterograde and retrograde transport. Chlamydomonas reinhardtii is a commonly used model to study the mechanisms of how the flagella organelle functions because its flagella organelle is highly conserved and similar to human cilia and flagella. One route in which to study the flagella organelle is through the creation and analysis of flagellar mutants. Six possible C. reinhardtii IFT mutants (created from a previous transformation process and confirmed through a phototaxis test) were chosen to perform PCR on. These regions of disrupted DNA used for PCR were hypothesized to be related to IFT. The DNA was sent to be sequenced in order to determine what sections of the C. reinhardtii genome were disrupted by the transformation process. Conclusive results are currently being determined. The consequences of improper functioning flagella can be devastating to a cell. Through this research, the flagella organelle and its IFT processes can be better understood, and the findings may even aid in the discovery of cures for flagellar diseases (such as polycystic disease, retinitis pigmentosa, etc.).

Hernandez, Catherine Marie

2013-05-01T23:59:59.000Z

90

Quantifying the Air Pollution Exposure Consequences of Distributed Electricity Generation  

E-Print Network (OSTI)

RP. 1982. Handbook on Atmospheric Diffusion. DOE/TIC-11223.RP. 1982. Handbook on Atmospheric Diffusion. DOE/TIC-11223.

Heath, Garvin A.; Granvold, Patrick W.; Hoats, Abigail S.; Nazaroff, William W

2005-01-01T23:59:59.000Z

91

Effects of Terrain Heights and Sizes on Island-Scale Circulations and Rainfall for the Island of Hawaii during HaRP  

Science Conference Proceedings (OSTI)

Islands in Hawaii have different sizes and terrain heights with notable differences in climate and weather. In this study, the fifth-generation Pennsylvania State UniversityNCAR Mesoscale Model (MM5) land surface model (LSM) is used to conduct ...

Yang Yang; Yi-Leng Chen

2008-01-01T23:59:59.000Z

92

Development of a Toolkit for Calculating Linear, Change-Point Linear and Multiple-Linear Inverse Building Energy Analysis Models, ASHRAE Research Project 1050-RP, Final Report  

E-Print Network (OSTI)

This report summarizes the results of ASHRAE Research Project 1050: Development of a Toolkit for Calculating Linear, Change-Point Linear and Multiple Linear Inverse Building Energy Analysis Models. The Inverse Modeling Toolkit (WIT) is a FORTRAN 90 application for developing regression models of building energy use. IMT can identify single and multi-variable least-squares regression models. It can also identify variable-base degree-day and single and multi-variable change-point models, which have been shown to be especially useful for modeling building energy use. This report includes background information about IMT and the models, instructions for its installation and operation, and the results of accuracy and robustness testing.

Kissock, J. K.; Haberl, J. S.; Claridge, D. E.

2002-11-01T23:59:59.000Z

93

Materials Reliability Program: Risk Assessment of ASME Section XI Appendix G Pressure-Temperature (P-T) Limit Curve Methodologies (M RP-368)  

Science Conference Proceedings (OSTI)

This report presents the results of an assessment of the conditional probability of reactor pressure vessel (RPV) failure in pressurized water reactors (PWRs) when normal RPV heatup and cooldown occur along operational constraint boundaries. These boundaries are defined by the maximum allowable pressures determined from regulatory requirements, the evaluation procedures in Appendix G to Section XI of the American Society of Mechanical Engineers (ASME) Boiler and Pressure Vessel Code (Appendix G), ...

2013-12-09T23:59:59.000Z

94

P a c e s e t t e rP a c e s e t t e r Texas Gulf Coast Restoration  

E-Print Network (OSTI)

in Gilchrist, Texas. Floodwaters from Hurricane Ike reportedly rose as high as eight feet in some areas causing operations at 29 of our 178 parks and access areas. We also con- sidered making the recreation season shorter- sibility of the administration and maintenance of selected areas. These actions led to the leasing of nine

US Army Corps of Engineers

95

In Reply Refer To: PostRock KPC Pipeline, LLC Docket No. RP12-173-000 PostRock KPC Pipeline, LLC  

E-Print Network (OSTI)

one-time waiver of Section 24.5 of the General Terms and Conditions (GT&C) of KPCs FERC Gas Tariff, Third Revised Volume No. 1. Section 24.5 requires that KPC file an interruptible transportation (IT) revenue crediting report with the Commission within sixty days of October 1 of each year. As discussed below, for good cause shown, the Commission grants a one-time waiver of Section 24.5 of KPCs GT&C. 2. Section 24.5 provides that KPC shall file an interruptible transportation (IT) revenue crediting report comparing (1) the total revenues collected pursuant to Rate Schedule IT during the twelve-month period ending September 30 against (2) the total cost of service allocated to be recovered under Rate Schedule IT during that period. To the extent such revenues exceed such cost of service allocation, KPC is required to credit 100 percent of the excess revenue, less applicable surcharges, penalties, and variable costs, to firm shippers serviced under Rate Schedules FT and FT-NN. Section 24.5 further provides that all firm shippers served under FT and FT-NN paying the maximum rate shall receive such credits. 3. KPC states that during the twelve-month period ending September 30, 2011, KPC

Matthew T. Rick; Attorney Postrock; Kpc Pipeline

2011-01-01T23:59:59.000Z

96

NON-REFEREED PUBLICATIONS Dunn, M.A., R.P. Vlosky, and T.F. Shupe. 2005. Homebuilders attitudes and  

E-Print Network (OSTI)

over 52,000 Little East Champions! Continued on page 6 Kinsey Durgin drives for a layup in class 3, Portrait of a Plant in Cultivation. She received third prize in class 4, Rock Garden Scene on a sophomore guard Tirrell Hill layup. Keene State threatened with 5:29 left to go, cutting the lead down

97

Microaneurysms detection with the radon cliff operator in retinal fundus images  

SciTech Connect

Diabetic Retinopathy (DR) is one of the leading causes of blindness in the industrialized world. Early detection is the key in providing effective treatment. However, the current number of trained eye care specialists is inadequate to screen the increasing number of diabetic patients. In recent years, automated and semi-automated systems to detect DR with color fundus images have been developed with encouraging, but not fully satisfactory results. In this study we present the initial results of a new technique for the detection and localization of microaneurysms, an early sign of DR. The algorithm is based on three steps: candidates selection, the actual microaneurysms detection and a final probability evaluation. We introduce the new Radon Cliff operator which is our main contribution to the field. Making use of the Radon transform, the operator is able to detect single noisy Gaussian-like circular structures regardless of their size or strength. The advantages over existing microaneurysms detectors are manifold: the size of the lesions can be unknown, it automatically distinguishes lesions from the vasculature and it provides a fair approach to microaneurysm localization even without post-processing the candidates with machine learning techniques, facilitating the training phase. The algorithm is evaluated on a publicly available dataset from the Retinopathy Online Challenge.

Giancardo, Luca [ORNL; Meriaudeau, Fabrice [ORNL; Karnowski, Thomas Paul [ORNL; Tobin Jr, Kenneth William [ORNL; Li, Yaquin [University of Tennessee, Knoxville (UTK); Chaum, Edward [University of Tennessee, Knoxville (UTK)

2010-01-01T23:59:59.000Z

98

Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion  

E-Print Network (OSTI)

, Changchun 130000, China; d Department of Ophthalmology, Harbin Medical University, The Second Affiliated Hospital, Harbin, Heilongjiang 150086, China; e National Center for Advancing Translational Sciences targets for the development of neuroprotective drugs, we developed a high-throughput RNA in- terference

Dong, Xinzhong

99

Challenging the Pathophysiologic Connection between Subdural Hematoma, Retinal Hemorrhage and Shaken Baby Syndrome  

E-Print Network (OSTI)

22. Greenes DS, Schutzman SA. Occult intracranial injury indiagnosis before settling on occult shaking as the de-factoskull fractures, were occult, without neurologic symptoms

Gabaeff, Steven C

2011-01-01T23:59:59.000Z

100

Enhanced visualization of retinal pathologies with ultrahigh resolution optical coherence tomography  

E-Print Network (OSTI)

Current clinical practice calls for the development of techniques to diagnose diseases in its early stages, when treatment is most effective and significant irreversible damage can either be prevented or delayed. Optical ...

Ko, Tony Hong-Tyng, 1975-

2005-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "retinitis pigmentosa rp" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


101

Molecular Evolution of Adeno-associated Virus for Improved Retinal Gene Therapies  

E-Print Network (OSTI)

D, Flannery J, et al. (2009) Molecular evolution of adeno-Brennan C, et al. (2004) Molecular diversity of astrocytesMolecular Evolution of Adeno-associated Virus for Improved

Klimczak, Ryan Raymond

2010-01-01T23:59:59.000Z

102

The Journal of Neuroscience, May 1997, 7(5): 1340-I 351 Effects of Early Unilateral Blur on the Macaque's Visual System.  

E-Print Network (OSTI)

,which abolishesvirtually all gatternedstimulation of the retina andsubstantiallyreduces retinal illuminati

Movshon, Joseph Anthony

103

J. Fluid Mech. (2004), vol. 527, pp. 2755. c 2004 Cambridge University Press DOI: 10.1017/S0022112004002575 Printed in the United Kingdom  

E-Print Network (OSTI)

. Tend to overpredict cooling loads. #12;ASHRAE 942-RP Comparison of ASHRAE and CIBSE load calculation

Linden, Paul F.

104

Candidate genes for chromosomes 6 and 10 quantitative trait loci for age-related retinal degeneration in mice  

E-Print Network (OSTI)

), complement factor B (CFB), and complement component 2 (C2), Chemokine (C-X3-C motif) receptor 1 (CX3CR1), Age to permanent exposure to reactive oxygen species generated by the absorption of light. Genes involved in gene expression should reflect an adjustment of blood flow for the oxygen requirement of the retina

Dahlquist, Kam D.

105

IEEE TRANSACTIONS ON NEURAL NETWORKS, VOL. 15, NO. 5, SEPTEMBER 2004 1083 Stimulus-Specific Oscillations in a Retinal Model  

E-Print Network (OSTI)

was supported in part by the Department of Energy Office of Nonproliferation Research and Engineering, in part

Theiler, James

106

Longitudinal Studies utilizing Local Neural Retinal Function, measured by Multifocal Electroretinograms, for the Prediction of Diabetic Eye Disease  

E-Print Network (OSTI)

SE, Cruickshanks KJ. The Wisconsin Epidemiologic Study oftype 2 diabetes: XXI: the Wisconsin Epidemiologic Study ofJAMA University of Wisconsin Department of Ocular

Harrison, Wendy Watkins

2011-01-01T23:59:59.000Z

107

Retinal ganglion cell survival and axon regeneration in WldS transgenic rats after optic nerve crush and lens injury  

E-Print Network (OSTI)

the latter inactive in WldS trans- genic rats. WldS is a fusion protein that consists of nicotinamide mononucleotide adenylyl-transferase-1 (Nmnat1) and a short fragment of the ubiquitin assem- bly protein UFD2. Whilst several reports have suggested... - fered saline (PBS) followed by 4% paraformaldehyde. Eyes and optic nerves were removed and post-fixed by immersion overnight in cold 4% paraformaldehyde. Tis- sue was then washed with PBS and transferred to 30% sucrose solution (overnight at 4 C...

Lorber, Barbara; Tassoni, Alessia; Bull, Natalie D; Moschos, Marilita M; Martin, Keith R

2012-06-06T23:59:59.000Z

108

Color vision is achieved by comparing the inputs from retinal photoreceptor neurons that differ in their wavelength  

E-Print Network (OSTI)

, the distinction between short- and long-fiber systems is clear: the short- fiber photoreceptors R1­R6 are optically and physiologically independent from one another [24], whereas the long-fiber photoreceptors R7. Armett-Kibel C, Meinertzhagen I: The long visual fibers of the Dragonfly optic lobe: their cells

Desplan, Claude

109

Color vision is achieved by comparing the inputs from retinal photoreceptor neurons that differ in their wavelength  

E-Print Network (OSTI)

systems is clear: the short- fiber photoreceptors R1­R6 are optically and physiologically independent from short visual fibers projecting to the lamina part of the optic lobe. They may correspond to the rods detection [20,21]. The other system is represented by the long visual fibers that project to the medulla

110

Classification and Localisation of Diabetic-Related Eye Disease  

Science Conference Proceedings (OSTI)

Retinal exudates are a characteristic feature of many retinal diseases such as Diabetic Retinopathy. We address the development of a method to quantitatively diagnose these random yellow patches in colour retinal images automatically. After a colour ...

Alireza Osareh; Majid Mirmehdi; Barry T. Thomas; Richard Markham

2002-05-01T23:59:59.000Z

111

Trends in Energy Management Technology - Part 4: Review of Advanced Applications in Energy Management, Control, and Information Systems  

E-Print Network (OSTI)

www.nist.gov/tc411/1043-RP_FDD_Literature_Review.pdf Smith,Energy Commission, Fall 1999. FDD for Rooftop AC Purduewww.nist.gov/tc411/1043-RP_FDD_Tools.pdf IMDS Lawrence

Yee, Gaymond; Webster, Tom

2003-01-01T23:59:59.000Z

112

U.S. DEPARTMENT OF ENERGY - NETL CATEGORICAL EXCLUSION (CX) DESIGNATIO...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

efficiency and renewable energy projects at 3 state campuses for the developmentally disabled. Complete CX. R.P. Detwiler Digitally signed by R.P. Detwiler DN: cnR.P. Detwiler,...

113

Neural systems for preparatory and reactive imitation control  

E-Print Network (OSTI)

37. Iacoboni M, Woods RP, Brass M, Bekkering H, MazziottaCatmur C, Liepelt R, Brass M, Heyes C. (2008). Experience-240. Iacoboni M, Woods RP, Brass M, Bekkering H, Mazziotta

Cross, Katy

2013-01-01T23:59:59.000Z

114

Study of Molecular and Biological Properties of Citrus exocortis viroid and Dweet mottle virus  

E-Print Network (OSTI)

oxygenase, endo-peptidase, helicase, and RNA-dependent RNAOxygenase protein; Hel: Helicase; RdRP: RNA-dependent RNAOxygenase protein; Hel: Helicase; RdRP: RNA-dependent RNA

Hajeri, Subhas

2010-01-01T23:59:59.000Z

115

U.S. DEPARTMENT OF ENERGY - NETL CATEGORICAL EXCLUSION (CX) DESIGNATIO...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

heat sink is mine pool water beneath campus. No surface discharge or mixture with chilled water system R.P. Detwiler Digitally signed by R.P. Detwiler DN: cnR.P. Detwiler,...

116

Dynamic predictive clothing insulation models based on outdoor air and indoor operative temperatures  

E-Print Network (OSTI)

preference. Final Report ASHRAE RP-884 1997. [10] FarawayArid Climate. Final Report ASHRAE RP-921 1998. Schiavon S,buildenv.2012.08.024 [14] ANSI/ASHRAE. ANSI/ASHRAE 55-1992:

Schiavon, Stefano; Lee, Kwang Ho

2012-01-01T23:59:59.000Z

117

U.S. DEPARTMENT OF ENERGY - NETL CATEGORICAL EXCLUSION (CX) DESIGNATIO...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

MD-Rev1 State Agency Loans Programs Loans for state agencies' small scale energy efficiency measures 11 06 2009 R.P. Detwiler Digitally signed by R.P. Detwiler DN: cnR.P....

118

Additive Manufacturing of Nickel-Base Superalloys - Programmaster ...  

Science Conference Proceedings (OSTI)

... Corrosion Inhibition for Hydrochloric Acid Pickling Using Resistance Heating to Create Full-Scale API RP2Z CTOD Samples...

119

Comparison of Point-Defect Evolution in Irradiated UO2 and Ceo2 ...  

Science Conference Proceedings (OSTI)

... Corrosion Inhibition for Hydrochloric Acid Pickling Using Resistance Heating to Create Full-Scale API RP2Z CTOD Samples...

120

Brazing of Titanium Alloys Using Low-melting Eutectic Zr-Ti-Ni(Cu)  

Science Conference Proceedings (OSTI)

... Corrosion Inhibition for Hydrochloric Acid Pickling Using Resistance Heating to Create Full-Scale API RP2Z CTOD Samples...

Note: This page contains sample records for the topic "retinitis pigmentosa rp" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


121

Novel Opencell Metal Sandwich Panels - Programmaster.org  

Science Conference Proceedings (OSTI)

... Corrosion Inhibition for Hydrochloric Acid Pickling Using Resistance Heating to Create Full-Scale API RP2Z CTOD Samples...

122

Martensite Strain Induced Phase Transformation and Corrosion ...  

Science Conference Proceedings (OSTI)

... Corrosion Inhibition for Hydrochloric Acid Pickling Using Resistance Heating to Create Full-Scale API RP2Z CTOD Samples...

123

Influence of Heterogeneous Deformation on Microstructural ...  

Science Conference Proceedings (OSTI)

... Corrosion Inhibition for Hydrochloric Acid Pickling Using Resistance Heating to Create Full-Scale API RP2Z CTOD Samples...

124

Steel Design for Blast and Fragment Protection - Programmaster.org  

Science Conference Proceedings (OSTI)

... Corrosion Inhibition for Hydrochloric Acid Pickling Using Resistance Heating to Create Full-Scale API RP2Z CTOD Samples...

125

Friction Stir Processing of Cast Superalloys  

Science Conference Proceedings (OSTI)

... Corrosion Inhibition for Hydrochloric Acid Pickling Using Resistance Heating to Create Full-Scale API RP2Z CTOD Samples...

126

Hot Deformation Behavior of Ti-6Al-4V Alloy with a' Martensite ...  

Science Conference Proceedings (OSTI)

... Corrosion Inhibition for Hydrochloric Acid Pickling Using Resistance Heating to Create Full-Scale API RP2Z CTOD Samples...

127

Static Recrystallization Behavior of Co-Ni-Cr-Mo Superalloy after ...  

Science Conference Proceedings (OSTI)

... Corrosion Inhibition for Hydrochloric Acid Pickling Using Resistance Heating to Create Full-Scale API RP2Z CTOD Samples...

128

Stress-Rupture Behavior of Single Crystal Superalloy M09A  

Science Conference Proceedings (OSTI)

... Corrosion Inhibition for Hydrochloric Acid Pickling Using Resistance Heating to Create Full-Scale API RP2Z CTOD Samples...

129

Influence of Sulfide on Internal-Fracture-Type Rolling Contact ...  

Science Conference Proceedings (OSTI)

... Corrosion Inhibition for Hydrochloric Acid Pickling Using Resistance Heating to Create Full-Scale API RP2Z CTOD Samples...

130

Characterization of Ni-Base Superalloy Die Materials  

Science Conference Proceedings (OSTI)

... Corrosion Inhibition for Hydrochloric Acid Pickling Using Resistance Heating to Create Full-Scale API RP2Z CTOD Samples...

131

General Abstracts: Structural Materials Division  

Science Conference Proceedings (OSTI)

... Corrosion Inhibition for Hydrochloric Acid Pickling Using Resistance Heating to Create Full-Scale API RP2Z CTOD Samples...

132

IAIFORIUA'IW3NPWCE!SSiNG LET MRS l(l971) 6%68.NORTH-HOLLAND PUBLISHING CY)@ANY Ret&ted 30 April 19' i  

E-Print Network (OSTI)

(rP~). Thereffxe, an nth . c . polynomsal can be evaluated at fi porn;;; 141) operations,andatn pointsin

Borodin, Allan

133

booklist  

Science Conference Proceedings (OSTI)

... Birkhauser, Basel, 1969; English translation, Pergamon Press, Oxford, 1971. ... Translated from the Russian by RP Boas, Birkhauser, Basel, 1988. ...

2000-02-17T23:59:59.000Z

134

Correction: Analysis of a zebrafish dync1h1 mutant reveals multiple functions for cytoplasmic dynein 1 during retinal photoreceptor development  

E-Print Network (OSTI)

Anatomy, Medical College of Wisconsin, 8701 Watertown PlankAnatomy, Medical College of Wisconsin, 8701 Watertown Plank

Insinna, Christine; Baye, Lisa M; Amsterdam, Adam; Besharse, Joseph C; Link, Brian A

2010-01-01T23:59:59.000Z

135

Bryant fall 2010 FCP H I L A N T H R O P Y I N A C T I O N FA L L/WI NTER2011ABRyA NTUN IvE RsITyREsoURcEFo RP Ro FEssIoNALsUccEss  

E-Print Network (OSTI)

to a series of convenience store robberies in Baltimore County. This work was supported by National Institute to the Baltimore County Police Department and especially to Phil Canter. #12;MULTIMODEL INFERENCE AND GEOGRAPHIC of papers by Akaike (1973, 1974, 1977), and an excellent description of the relevant theory and applications

Blais, Brian

136

DEVELOPMENT OF A NATURAL GAS SYSTEMS ANALYSIS MODEL (GSAM) VOLUME I - SUMMARY REPORT VOLUME II - USER'S GUIDE VOLUME IIIA - RP PROGRAMMER'S GUIDE VOLUME IIIB - SRPM PROGRAMMER'S GUIDE VOLUME IIIC - E&P PROGRAMMER'S GUIDE VOLUME IIID - D&I PROGRAMMER'S GUIDE  

SciTech Connect

This report summarizes work completed on DOE Contract DE-AC21-92MC28138, Development of a Natural Gas Systems Analysis Model (GSAM). The products developed under this project directly support the National Energy Technology Laboratory (NETL) in carrying out its natural gas R&D mission. The objective of this research effort has been to create a comprehensive, non-proprietary, microcomputer model of the North American natural gas market. GSAM has been developed to explicitly evaluate components of the natural gas system, including the entire in-place gas resource base, exploration and development technologies, extraction technology and performance parameters, transportation and storage factors, and end-use demand issues. The system has been fully tested and calibrated and has been used for multiple natural gas metrics analyses at NETL in which metric associated with NETL natural gas upstream R&D technologies and strategies under the direction of NETL has been evaluated. NETL's Natural Gas Strategic Plan requires that R&D activities be evaluated for their ability to provide adequate supplies of reasonably priced natural gas. GSAM provides the capability to assess potential and on-going R&D projects using a full fuel cycle, cost-benefit approach. This method yields realistic, market-based assessments of benefits and costs of alternative or related technology advances. GSAM is capable of estimating both technical and commercial successes, quantifying the potential benefits to the market, as well as to other related research. GSAM, therefore, represents an integration of research activities and a method for planning and prioritizing efforts to maximize benefits and minimize costs. Without an analytical tool like GSAM, NETL natural gas upstream R&D activities cannot be appropriately ranked or focused on the most important aspects of natural gas extraction efforts or utilization considerations.

Unknown

2001-02-01T23:59:59.000Z

137

Processing - Programmaster.org  

Science Conference Proceedings (OSTI)

Mar 3, 2011 ... Using Resistance Heating to Create Full-Scale API RP2Z CTOD Samples: Morgan Gallagher1; Sudarsanam Suresh Babu2; Jerry Gould1;...

138

William Charlis MBADINGA LES POURPARLERS DE PAIX  

E-Print Network (OSTI)

suppléments, 1903- 1978. RIB R.G. Collingwood et R.P. Wright, The Roman Inscriptions of Britain, Oxford, puis

139

Recrystallization Behavior of Cold Rolled Alloy 718  

Science Conference Proceedings (OSTI)

Columbus, Ohio & ASM International, Materials Park, Ohio, (1990). 8). R.P. Singh : Ph.D. Thesis, Drexel University, Philadelphia, PA , (1987). 215.

140

cast shop technology i  

Science Conference Proceedings (OSTI)

Upgradation of Alumina Refinery at Hindalco Renukoot (India) R.P. Shah and .... The Influence of Crude Oil Desalting on Calcined Coke Quality (abstract only)

Note: This page contains sample records for the topic "retinitis pigmentosa rp" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


141

Alternative Fuel Vehicles: The Case of Compressed Natural Gas (CNG) Vehicles in California Households  

E-Print Network (OSTI)

Infrastructure F. Current California CNG Vehicle UseCharacteristics of CNG Vehicles Review of Previous Studies/RP) Studies of AFVs/CNG Vehicles i. British Columbia, Canada

Abbanat, Brian A.

2001-01-01T23:59:59.000Z

142

Numerical Simulations of Grassland Fire Behavior from the ...  

Science Conference Proceedings (OSTI)

... dimensions are applied to wind driven grassland fires over flat terrain. ... USDA Forest Service, Rocky Mountain Research Station Paper, RMRS-RP-4 ...

2010-01-21T23:59:59.000Z

143

[Prioleau] Prioleau, Frost, SLA, SLS, and CNC: Comparing ...  

Science Conference Proceedings (OSTI)

... "water-tight". ... building envelopes of available RP systems, the tightest tolerances are ... parts as patterns for investment castings and sand castings, as ...

1994-04-01T23:59:59.000Z

144

Using CFD Capabilities of CONTAM 3.0 for Simulating Airflow ...  

Science Conference Proceedings (OSTI)

... CFD0 was a CFD program originally developed for ASHRAE research project RP-927 (Chen et al. 1999), and improved by Wang (2007). ...

2010-11-09T23:59:59.000Z

145

REPORT OF THE UNITED STATES EMBASSY SCIENCE FELLOWS SUPPORT TO ...  

srnl?rp?2013?00303 epa/600/r?13/135 revision 0 report of the united states embassy science fellows support to the

146

OOMMF 1.2a3 Patches  

Science Conference Proceedings (OSTI)

... (Thanks to RP Boardman for reporting this.) Solution: Apply this patch, and if you haven't already, also the the patch at item 3, and rerun pimake. ...

2011-07-01T23:59:59.000Z

147

NISTIR 6991  

Science Conference Proceedings (OSTI)

... 187-207 (1992). [18] B. Bedal and H. Nguyen, Advances in Part Accuracy, in: Stereolithography and Other RP&M Processes, PF Jacobs, American ...

2013-04-24T23:59:59.000Z

148

STATEMENT OF CONSIDERATIONS CLASS ADVANCE WAIVER OF THE GOVERNMENT...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

le - 003 STATEMENT OF CONSIDERATIONS CLASS ADVANCE WAIVER ASCI RP No. PF-01 high performance computing technologies that would subaoquantly be economically sustained in the...

149

Historical Publications of the Electron Physics Group, 1980 ...  

Science Conference Proceedings (OSTI)

... of Spin Polarized Secondary Electrons in Transition ... Analysis in a Scanning Electron Microscope, J. Unguris ... and DT Pierce, J. Microscopy 139, RP1 ...

2013-04-26T23:59:59.000Z

150

RapidProto  

NLE Websites -- All DOE Office Websites (Extended Search)

Prototyping Manufacturing Technologies The Rapid Prototyping Laboratory (RPL) supports internal design, manufacturing, and process develop- ment with three rapid prototyping (RP)...

151

Manufacturing Science and Technology: Technologies  

NLE Websites -- All DOE Office Websites (Extended Search)

Courtesy of ZCorp The Rapid Prototyping Laboratory (RPL) supports internal design, manufacturing, and process development with three rapid prototyping (RP) technologies:...

152

Design methods for displacement ventilation: Critical review.  

E-Print Network (OSTI)

Displacement Ventilation. ASHRAE Research project-RP-949.displacement ventilation. ASHRAE Transaction, 96 (1). Ar ???due to displacement ventilation. ASHRAE Transaction, 96 (1).

Schiavon, Stefano

2006-01-01T23:59:59.000Z

153

Sawtooth oscillations in a damped/driven cryogenic electron plasma: Experiment and theory  

E-Print Network (OSTI)

and is of fixed length. The evolution equations for the three parameters are then d dt T 2 3 NLe2 2 D2 Rp 2 1 Rp temperature, Tmin , given by Tmin 2 3 NLe2 rad Tw . 8 Tmin is the minimum temperature to which the plasma can , D 2NLe2 1 Rp 2 Rw 2 D2 Rp 2 , we can rewrite Eqs. 5 and 6 as d dt T D T rad , 9 d dt D 2 D, 10 where

California at San Diego, University of

154

Quantum state tomography of a fiber-based source of ...  

Science Conference Proceedings (OSTI)

... 2. RP Feynman, RB Leighton, RB and ML Sands, The Feynman Lectures ... fiber because the centro- symmetry of single-mode fiber glass allows no ...

2010-08-19T23:59:59.000Z

155

Predictive Factors for Radiation Pneumonitis in Hodgkin Lymphoma Patients Receiving Combined-Modality Therapy  

SciTech Connect

Purpose: This study sought to quantify the risk of radiation pneumonitis (RP) in Hodgkin lymphoma (HL) patients receiving mediastinal radiation therapy (RT) and to identify predictive factors for RP. Methods and Materials: We identified 75 patients with newly diagnosed HL treated with mediastinal RT and 17 patients with relapsed/refractory HL treated with mediastinal RT before or after transplant. Lung dose-volumetric parameters including mean lung dose and percentage of lungs receiving 20 Gy were calculated. Factors associated with RP were explored by use of the Fisher exact test. Results: RP developed in 7 patients (10%) who received mediastinal RT as part of initial therapy (Radiation Therapy Oncology Group Grade 1 in 6 cases). A mean lung dose of 13.5 Gy or greater (p = 0.04) and percentage of lungs receiving 20 Gy of 33.5% or greater (p = 0.009) significantly predicted for RP. RP developed in 6 patients (35%) with relapsed/refractory HL treated with peri-transplant mediastinal RT (Grade 3 in 4 cases). Pre-transplant mediastinal RT, compared with post-transplant mediastinal RT, significantly predicted for Grade 3 RP (57% vs. 0%, p = 0.015). Conclusions: We identified threshold lung metrics predicting for RP in HL patients receiving mediastinal RT as part of initial therapy, with the majority of cases being of mild severity. The risk of RP is significantly higher with peri-transplant mediastinal RT, especially among those who receive pre-transplant RT.

Fox, Amy M. [Department of Radiation Oncology, Brigham and Women's Hospital and Dana-Farber Cancer Institute, Boston, MA (United States); 21st Century Oncology, Fort Myers, FL (United States); Dosoretz, Arie P. [Department of Radiation Oncology, Brigham and Women's Hospital and Dana-Farber Cancer Institute, Boston, MA (United States); Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT (United States); Mauch, Peter M. [Department of Radiation Oncology, Brigham and Women's Hospital and Dana-Farber Cancer Institute, Boston, MA (United States); Chen, Yu-Hui [Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA (United States); Fisher, David C.; LaCasce, Ann S.; Freedman, Arnold S. [Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA (United States); Silver, Barbara [Department of Radiation Oncology, Brigham and Women's Hospital and Dana-Farber Cancer Institute, Boston, MA (United States); Ng, Andrea K., E-mail: ang@lroc.harvard.edu [Department of Radiation Oncology, Brigham and Women's Hospital and Dana-Farber Cancer Institute, Boston, MA (United States)

2012-05-01T23:59:59.000Z

156

SIMPLICITY OF NONCOMMUTATIVE DEDEKIND DOMAINS K. R. Goodearl and J. T. Stafford  

E-Print Network (OSTI)

. Stafford Abstract. The following dichotomy is established: A finitely generated, com* *plex. STAFFORD pR = Rp and (ii) R=P is a domain. These exist in profusion; for example, take the enveloping;4 K. R. GOODEARL AND J. T. STAFFORD We note that Lemma 4 also holds if the hypothesis "dimk R

Akhmedov, Azer

157

SIMPLICITY OF NONCOMMUTATIVE DEDEKIND DOMAINS K. R. Goodearl and J. T. Stafford  

E-Print Network (OSTI)

SIMPLICITY OF NONCOMMUTATIVE DEDEKIND DOMAINS K. R. Goodearl and J. T. Stafford Abstract X 1 #12; 2 K. R. GOODEARL AND J. T. STAFFORD pR = Rp and (ii) R=P is a domain. These exist. STAFFORD We note that Lemma 4 also holds if the hypothesis \\dim k R

Akhmedov, Azer

158

The homeobox transcription factor Even-skipped regulates acquisition of electrical properties in Drosophilaneurons  

E-Print Network (OSTI)

, 10 pA/500 ms, p ? 0.05; Figure 1d). Increased Eve regulates postsynaptic sensitivity to excitatory neurotransmitter We also measured synaptic input to aCC/RP2 following Over-expression of eve in aCC/RP2 is sufficient to alter elec-trical prop rties...

Pym, Edward C G; Southall, Tony D; Mee, Christopher J; Brand, Andrea H; Baines, Richard A

2006-11-16T23:59:59.000Z

159

Association of P53 and ATM Polymorphisms With Risk of Radiation-Induced Pneumonitis in Lung Cancer Patients Treated With Radiotherapy  

Science Conference Proceedings (OSTI)

Purpose: Radiation-induced pneumonitis (RP) is the most common dose-limiting complication in lung cancer patients treated with radiotherapy. Accumulating evidence indicates that P53 and the ataxia telangiectasia-mutated protein (ATM)-dependent signaling response cascade play a crucial role in radiation-induced diseases. Consistent with this, our previous study showed that a functional genetic ATM polymorphism was associated with increased RP risk. Methods and Materials: To evaluate the role of genetic P53 polymorphism in RP, we analyzed the P53 Arg72Pro polymorphism in a cohort including 253 lung cancer patients receiving thoracic irradiation. Results: We found that the P53 72Arg/Arg genotype was associated with increased RP risk compared with the 72Pro/Pro genotype. Furthermore, the P53 Arg72Pro and ATM -111G>A polymorphisms display an additive combination effect in intensifying the risk of developing RP. The cross-validation test showed that 63.2% of RP cases can be identified by P53 and ATM genotypes. Conclusions: These results indicate that genetic polymorphisms in the ATM-P53 pathway influence susceptibility to RP and genotyping P53 and ATM polymorphisms might help to identify patients susceptible to developing RP when receiving radiotherapy.

Yang Ming [Departments of Etiology and Carcinogenesis, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (China); Key Laboratory for Carcinogenesis and Cancer Prevention, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (China); Zhang Li [Department of Radiation Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (China); Bi Nan; Ji Wei [Department of Radiation Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (China); Tan Wen [Departments of Etiology and Carcinogenesis, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (China); Key Laboratory for Carcinogenesis and Cancer Prevention, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (China); Zhao Lujun [Department of Radiation Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (China); Yu Dianke; Wu Chen [Departments of Etiology and Carcinogenesis, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (China); Key Laboratory for Carcinogenesis and Cancer Prevention, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (China); Wang Luhua [Department of Radiation Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (China)

2011-04-01T23:59:59.000Z

160

80 IEEE TRANSACTIONS ON ULTRASONICS, FERROELECTRICS, AND FREQUENCY CONTROL, VOL. 36. NO. I. JANUARY 1989 Pattern Recognition in the Ultrasonic Imaging of  

E-Print Network (OSTI)

in steam generator tubing used in nuclear power plants. Various reverberant patterns can be recognized. The mathematical analysis of continuous wave propa- 11-[41. Manuscript received October 15, 1987; revised February 2.5, 1988. This work supported by Electric Power Research Institute (EPRI) grants RP2687- 3 and RP

Saniie, Jafar

Note: This page contains sample records for the topic "retinitis pigmentosa rp" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


161

Viirre, E., Pryor, H., Nagata, S., Furness, T. A. (1998). The Virtual Retinal Display: A New Technology for Virtual Reality and Augmented Vision in Medicine. In Proceedings of Medicine  

E-Print Network (OSTI)

into a fiber optic strand which brings light to the Mechanical Resonance Scanner (MRS) (patent pending technology. The power levels recorded from the system are several orders below the power levels prescribed and it can create images that can be seen in ambient daylight. The combination of high brightness

Washington at Seattle, University of

162

Artificial Retina In the News  

NLE Websites -- All DOE Office Websites (Extended Search)

retinal prostheses Neurotech Business Report, 2003 (free) Rays of hope for the blind Wall street Journal, August 27, 2003 (subscription required) Visionary implant: artificial...

163

NIST Micronutrients Measurement Quality Assurance Program ...  

Science Conference Proceedings (OSTI)

... For consistency, we request that laboratories use the following absorptivities (dL/g.cm): retinal, 1843 at 325 nm (ethanol); retinyl palmitate, 975 at ...

2013-08-07T23:59:59.000Z

164

NIST Micronutrients Measurement Quality Assurance Program ...  

Science Conference Proceedings (OSTI)

... For consistency, we request that laboratories use the following absorptivities (dL/gcm): retinal, 1843 at 325 nm (ethanol); retinyl palmitate, 975 at ...

2013-08-07T23:59:59.000Z

165

LANL Mobile News  

NLE Websites -- All DOE Office Websites (Extended Search)

LANL Home Phonebook Calendar Video Lab team makes unique contributions to the first bionic eye The Argus II will help people blinded by the rare hereditary disease retinitis...

166

Artificial Retina Video & Audio  

NLE Websites -- All DOE Office Websites (Extended Search)

Multimedia Presentations PBS logo NY Times: The FDA approves bionic eye February 2013 Video and article Second Sight logo Second Sight 2012 Argus II retinal prosthesis system...

167

Artificial Retina Project Progress  

NLE Websites -- All DOE Office Websites (Extended Search)

Technological Challenges in Engineering a Retinal Implant Photo of Eye with Silicon Chip The artificial retina consists of an electrode-studded soft polymer array (shown) that is...

168

ENVIRONMENTAL COMPLIANCE (EC)  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

RADIATION PROTECTION (RP) RADIATION PROTECTION (RP) OBJECTIVE RP.1: LANL line management has established Radiation Protection programs to ensure safe accomplishment of WCRR operations and maintenance activities within the requirements of the safety basis documents and regulatory permits. Sufficient numbers of qualified personnel as well as adequate facilities and equipment are available to support WCRRF operations. (CRs 1, 4, 6, and 7) CRITERIA 1. The LANL Radiation Protection Program has been effectively implemented in support of the full scope of WCRR operations including Bioassays, ALARA, RWPs, survey requirements, decontamination, etc. (10 CFR 835, WCRRF TSR 5.6.6) 2. An adequate number of radiation protection program personnel including RCTs, radiation

169

ORNL - Restart of the High Flux Isotope Reactor 2-07  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

RADIOLOGICAL PROTECTION (RP) RADIOLOGICAL PROTECTION (RP) OBJECTIVE RP-1: The RRD radiological protection program has been appropriately modified to reflect the CS modification and its reactor interface, sufficient numbers of qualified radiological protection personnel are provided, and adequate radiological protection facilities and equipment are available to ensure that services are adequate to conduct and support HFIR operation. The radiological protection functions, assignments, responsibilities, and reporting relationships are clearly defined, understood, and effectively implemented with line management control of safety. Radiological protection personnel exhibit awareness of the applicable radiological protection requirements pertaining to HFIR operation and the associated hazards.

170

Received 20 Oct 2012 | Accepted 29 Apr 2013 | Published 18 Jun 2013 Cortical responses elicited by photovoltaic  

E-Print Network (OSTI)

elicited by photovoltaic subretinal prostheses exhibit similarities to visually evoked potentials Yossi developed a wireless photovoltaic retinal prosthesis, in which camera- captured images are projected onto, yet the inner retinal neurons (inner nuclear and ganglion cell layers) that process the visual signals

Palanker, Daniel

171

Mercury and Methylmercury in the San Francisco Bay area: land-use impact and indicators  

E-Print Network (OSTI)

R.P. , and Flegal A. R. 2003, Mercury speciation in the SanAbdrashitova S. A. , 2001, Mercury in Aquatic Environment: A222 Hydrology for Planner Mercury and Methylmercury in the

Kim, Hyojin

2008-01-01T23:59:59.000Z

172

GTv26 (.txt) - CECM  

E-Print Network (OSTI)

These cycles form a basis for the ## cycle space of 'G', so that every other cycle in 'G' ...... 23, modified by MG # RP: help page combined with Degree InDegree...

173

Graduate Studies Committee Date: 3/22/2011  

E-Print Network (OSTI)

common kinetic systems. Soils 521 [Vyhnanek] Chemical equilibrium and kinetics of soil solution with specific applications to agricultural issues ES/RP 592 [Fassett] This course is used more and more by new

Collins, Gary S.

174

Determining Long-Term Performance of Cool Storage Systems from Short-Term Tests; Literature Review and Site Selection, Nov. 1997 (Revised Feb. 1998)  

E-Print Network (OSTI)

This is the preliminary report contains the literature review and site selection recommendations for ASHRAE Research Project RP 1004 "Determining Long-term Performance of Cool Storage Systems From Short-term Tests".

Haberl, J. S.; Claridge, D. E.; Reddy, T. A.; Elleson, J.

1997-01-01T23:59:59.000Z

175

Version_0and1_Matrix_of_Requirements_by_Function_06Mar07 AND...  

NLE Websites -- All DOE Office Websites (Extended Search)

GOP IA LSE PA PSE RC RP RRO RSG TO TOP TP TSP NERCNet CIP-002-1 R3. 612006 Critical Cyber Asset Identification - Using the list of Critical Assets developed pursuant to...

176

F&t++q/  

Office of Legacy Management (LM)

" , .-.-.. 2 - e . . ' . L' - rp- ' 24. *a .*+-sy&y- -- ->.. I1 &e *..* MAi? 29 1954 m.. maEQ---zAm y* " -- ' r--*r *?: -. - -.. ---em mco - 33 m-27 . ' . . . . . . , -a....

177

PERCOLATION ON THE PROJECTIVE PLANE  

E-Print Network (OSTI)

Since the projective plane is closed, the natural homological observable ofa percolation process is the presence ofthe essential cycle in H1(RP 2; Z2). In the Voroni model at critical phase, pc =.5, this observable has probability q =.5 independent ofthe metric on RP 2. This establishes a single instance (RP 2, homological observable) ofa very general conjecture about the conformal invariance ofpercolation due to Aizenman and Langlands, for which there is much moral and numerical evidence but no previously verified instances. On RP 2 all metrics are conformally equivalent so the proof of metric independence is precisely what the conjecture would predict. What is very special, is that at pc metric invariance holds in all finite models so passing to the limit is trivial; the probability q is fixed at.5 by a topological symmetry.

Michael H. Freedman

1997-01-01T23:59:59.000Z

178

Proc. Indian NatI. Sci. Acad.870 No. 5 & 6 pp 499-515 Melanism and Melanocortin-L Receptor Mutations in Vertebrates  

E-Print Network (OSTI)

et al. 1996; Miltenberger et al. 1999); and (5) the colorants acquired from the environment:607­612 Miltenberger RJ, Mynatt RL, Bruce BD, Wilkison WO, Woychik RP, Michaud EJ (1999) An agouti mutation lacking

Musselman, Lytton John

179

COMBINING STATED AND REVEALED CHOICE RESEARCH TO INFORM ENERGY SYSTEM  

E-Print Network (OSTI)

from a vehicle attribute database. RP dynamics were assessed by comparing models estimated from regions....................................................................................................33 2.2.2 Vehicle Database technologies, including choices among appliances (Nanduri, Tiedemann, & Bilodeau, 2002), energy suppliers

180

Shape Casting: The John Campbell Symposium TABLE OF ...  

Science Conference Proceedings (OSTI)

W. Sun, H.E. Littleton, and C.E. Bates. The Five Feeding Mechanisms [pp. 93] ... Pressure in Cast Aluminum Alloys [pp. 113] J.T. Berry, R. Luck, and R.P. Taylor...

Note: This page contains sample records for the topic "retinitis pigmentosa rp" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


181

Operating Experience Summary 2003-02  

NLE Websites -- All DOE Office Websites (Extended Search)

resulted from this event. (ORPS Re- port RP--BNRP-RPPWTP-2002-0012) A search of the ORPS database identified several other events in recent years where a truck snagged and pulled...

182

U.S. DEPARTMENT OF ENERGY - NETL CATEGORICAL EXCLUSION (CX) DESIGNATIO...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

SEP Matching grants to state and other recipient for the purchase of equipment for CNG fueling stations. Funds not used for construction of stations. Complete CX. R.P....

183

A NEWTON-PICARD APPROACH FOR EFFICIENT NUMERICAL ...  

E-Print Network (OSTI)

Due to P being an exact injection, it follows that PTMfP = Mc and thus. RP = I. .... The existence of the matrices V and W, as well as conditions. (i) and (ii) follow...

184

A putative new ampelovirus associated with grapevine leafroll disease  

E-Print Network (OSTI)

01660) [26], and viral helicase superfamily 1 (HEL, pfamencoded by GLRaV-Pr and -9. Helicase was the most conservedmethyltrans- ferase; HEL helicase; RdRp RNA-dependent RNA

Abou Ghanem-Sabanadzovic, N.; Sabanadzovic, S.; Uyemoto, J. K.; Golino, D.; Rowhani, A.

2010-01-01T23:59:59.000Z

185

PPT Slide  

U.S. Energy Information Administration (EIA)

The global resource base shown is the mean USGS ... a later peak results in a steeper decline rate, ... The reason for setting R/P equal to 10 is based on the United ...

186

Federal Register Volume 64 Number 159; Wednesday, August 18,...  

NLE Websites -- All DOE Office Websites (Extended Search)

Doc. 99-21410 Filed 8-17-99; 8:45 am BILLING CODE 6717-01-M DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Docket No. RP99-466-000 Great Lakes Gas Transmission...

187

Page not found | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

rp-impl-10-05-06finaldoc Article Secretary Chu Announces Six Projects to Convert Captured CO2 Emissions from Industrial Sources into Useful Products 106 Million Recovery Act...

188

Design and Installation of a Disposal Cell Cover Field Test  

Energy.gov (U.S. Department of Energy (DOE))

Paper presented at the Waste Management 2011 Conference.February 27 through March 3, 2011, Phoenix, Arizona.C.H. Benson, W.J. Waugh, W.H. Albright, G.M. Smith, R.P. Bush

189

SCOSTA-CL Specifications v 1.2 Issue Date July 06, 2007  

E-Print Network (OSTI)

image (f,(R,) + F,,)/FP = R;/FP. Thus Ri/FD s k(p), a field, and so FP is a maximal ideal of Rp'. We

Moona, Rajat

190

U.S. DEPARTMENT OF ENERGY - NETL CATEGORICAL EXCLUSION (CX) DESIGNATIO...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

PA Rev1- PA Energy Harvest Mined Grants - Bensalem Township Integration of 104 kW solar rooftop system (flexible membrane) onto township building R.P. Detwiler Digitally...

191

1 Introduction  

E-Print Network (OSTI)

Another approach to deal with the nondifferentiability is to use the so-called log- .... i=1 be a training set, where Xi ? Rp is a row vector and ..... A systematic.

192

Non-linear Seismic Soil Structure Interaction Method for Developing...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

OF A HIGH- TEMPERATURE GAS-COOLED REACTOR (HTGR)" Kennedy, R.P. e.t. all. 1975 * NUREGCR-6957, CORRELATION OF ANALYSIS OF JNES SEISMIC WALL PRESSURE DATA FOR ABWR MODEL...

193

Correlations between Ambient Noise and the Ocean Surface Wave Field  

Science Conference Proceedings (OSTI)

Measurements of the ambient noise spectrum level N with simultaneous, coincident wind and wave measurements were made from RP FLIP in fall 1991. The measurements were designed to investigate the correlation between the ambient noise and relevant ...

Francis C. Felizardo; W. Kendall Melville

1995-04-01T23:59:59.000Z

194

Energy saving and improved comfort by increased air movement  

E-Print Network (OSTI)

Change. Full report, Working Group III of the IPCC, ASHRAE,ASHRAE Standard 55, Thermal environmental conditions forMovement. Evaluation of ASHRAEs Draft (RP-843), in: HVAC&R

Schiavon, Stefano; Melikov, Arsen

2008-01-01T23:59:59.000Z

195

MODELING OF STANDING COLUMN WELLS IN GROUND SOURCE HEAT PUMP SYSTEMS  

E-Print Network (OSTI)

thanks go to Rob, absolutely for everything. This work was partially supported by the ASHRAE RP-1119, and partially supported by an ASHRAE Grant-in-Aid scholarship. ASHRAE's support is gratefully acknowledged. #12

196

Presented at the ASHRAE Winter Meeting, Atlanta, GA, February 17-21, 1996, and published in the Proceedings. Calorimetric Measurements of Inward-Flowing Fraction  

E-Print Network (OSTI)

LBL-37038 Mo-346 Presented at the ASHRAE Winter Meeting, Atlanta, GA, February 17-21, 1996 was jointly supported by ASHRAE, as Research Project 548-RP under Agreement No. BG 87-127 with the U

197

ARM - Publications: Science Team Meeting Documents  

NLE Websites -- All DOE Office Websites (Extended Search)

Retrieval of Ice Water Path Using Thermal Channels Mitchell, D.L. (a), d'Entremont, R.P. (b), Stackhouse, P.W., Jr. (c), and Heymsfield, A.J. (d), Desert Research Institute (a),...

198

Priority I and II Experiments Approved at the November 2-3, 2007...  

NLE Websites -- All DOE Office Websites (Extended Search)

understanding of the triple-alpha process in hot astrophysical scenarios 8 1184-2 J. Clark Mass measurements around 92Pd relevant for the rp-process and the new vp-process 7...

199

Best Practice for Energy Efficient Cleanrooms: Fan-Filter Units  

E-Print Network (OSTI)

control F iltra ti on ? Fan Efficiency ? Right Sizing ?Energy Performance of Fan-Filte r Units, Version 1.3 (2005),RP36.1 (Draft). Testing Fan-Filter Units. Draft Recommended

Xu, Tengfang

2005-01-01T23:59:59.000Z

200

AAS, Jan 7 2010 Observing the birth and evolution of the  

E-Print Network (OSTI)

, Toby Marriage, Lucas Parker, Paula Aguirre, Michele Limon, Tom Essinger-Hileman , Joe Fowler, Bruce T. Essinger-Hileman 6 R.P. Fisher 6 J. W. Fowler 6 A. Hajian 6 M. Halpern 5 M. Hasselfield 5 C

Note: This page contains sample records for the topic "retinitis pigmentosa rp" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


201

Energy Efficiency Improvement and Cost Saving Opportunities for the Fruit and Vegetable Processing Industry. An ENERGY STAR Guide for Energy and Plant Managers  

E-Print Network (OSTI)

efficiency actions, develop an energy management plan forE. Worrell (1995). Clean Energy Technologies: A PreliminarySingh, R.P. (1986a). Energy Accounting in Food Canning

Masanet, Eric

2008-01-01T23:59:59.000Z

202

A new implementation of high-throughput five-dimensional clone pooling strategy for BAC library screening  

E-Print Network (OSTI)

PP), column super-pools (CSP), and row super-pools (RSP) isa positive plate RSP, plate CSP, clone RP and clone CP forof plate RSP and plate CSP in the super pool 2-D design

You, Frank M; Luo, Ming-Cheng; Xu, Kenong; Deal, Karin R; Anderson, Olin D; Dvorak, Jan

2010-01-01T23:59:59.000Z

203

Exploring a unique vision for heavy ion fusion  

E-Print Network (OSTI)

ra in Fig. 20. Actual 2-D hydro implosion calculations willassuming input goes both to hydro @EbpA 2 / is %& Ebo ! rpAas a guide to motivate hydro code calculations for 2-D polar

Logan, B.G.

2008-01-01T23:59:59.000Z

204

Department  

NLE Websites -- All DOE Office Websites (Extended Search)

Requestfor Proposals(RFP)No.DE-RP36-8G010219. Photovoltaic-Technology Specific Super Energy Savings Perfonnance Contract (PV SUPER ESPC) Solicitation for U.S. Department of...

205

Microsoft PowerPoint - Deepwater Horizon Containment - 30 JUN...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

450 500 Cumulative Recovered, Thousands Barrels Cum. LM RP Cap Cum. Q4000 Daily Total Oil Recovered: LMRP Cap + Q4000 (Approximate volumes) Does not include 22,000 barrels...

206

Cambrian Wind Energy | Open Energy Information  

Open Energy Info (EERE)

London, Greater London, United Kingdom Zip W1U 6RP Sector Renewable Energy, Wind energy Product UK wind energy company acquired by Falck Renewables Ltd, the wind energy subsidiary...

207

ATM Polymorphisms Are Associated With Risk of Radiation-Induced Pneumonitis  

SciTech Connect

Purpose: Since the ataxia telangiectasia mutated (ATM) protein plays crucial roles in repair of double-stranded DNA breaks, control of cell cycle checkpoints, and radiosensitivity, we hypothesized that variations in this gene might be associated with radiation-induced pneumonitis (RP). Methods and Materials: A total of 253 lung cancer patients receiving thoracic irradiation between 2004 and 2006 were included in this study. Common Terminology Criteria for Adverse Events version 3.0 was used to grade RP. Five haplotype-tagging single nucleotide polymorphisms (SNPs) in the ATM gene were genotyped using DNA from blood lymphocytes. Hazard ratios (HRs) and 95% confidence intervals (CIs) of RP for genotypes were computed by the Cox model, adjusted for clinical factors. The function of the ATM SNP associated with RP was examined by biochemical assays. Results: During the median 22-month follow-up, 44 (17.4%) patients developed grade {>=} 2 RP. In multivariate Cox regression models adjusted for other clinical predictors, we found two ATM variants were independently associated with increased RP risk. They were an 111G > A) polymorphism (HR, 2.49; 95% CI, 1.07-5.80) and an ATM 126713G > A polymorphism (HR, 2.47; 95% CI, 1.16-5.28). Furthermore, genotype-dependent differences in ATM expression were demonstrated both in cell lines (p < 0.001) and in individual lung tissue samples (p = 0.003), which supported the results of the association study. Conclusions: Genetic polymorphisms of ATM are significantly associated with RP risk. These variants might exert their effect through regulation of ATM expression and serve as independent biomarkers for prediction of RP in patients treated with thoracic radiotherapy.

Zhang Li [Department of Radiation Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (China); Yang Ming [Department of Etiology and Carcinogenesis, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (China); Bi Nan [Department of Radiation Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (China); Fang Mingjing; Sun Tong [Department of Etiology and Carcinogenesis, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (China); Ji Wei [Department of Radiation Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (China); Tan Wen [Department of Etiology and Carcinogenesis, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (China); Zhao Lujun [Department of Radiation Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (China); Yu Dianke [Department of Etiology and Carcinogenesis, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (China); Lin Dongxin, E-mail: dlin@public.bta.net.c [Department of Etiology and Carcinogenesis, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (China); Wang Luhua, E-mail: wlhwq@yahoo.co [Department of Radiation Oncology, Cancer Institute and Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (China)

2010-08-01T23:59:59.000Z

208

Workbook Contents  

U.S. Energy Information Administration (EIA) Indexed Site

Annual",2012,"6/30/1936" Annual",2012,"6/30/1936" ,"Release Date:","9/27/2013" ,"Next Release Date:","9/26/2014" ,"Excel File Name:","pet_pnp_refp_dc_nus_mbbl_a.xls" ,"Available from Web Page:","http://www.eia.gov/dnav/pet/pet_pnp_refp_dc_nus_mbbl_a.htm" ,"Source:","Energy Information Administration" ,"For Help, Contact:","infoctr@eia.gov" ,,"(202) 586-8800",,,"11/25/2013 11:25:40 AM" "Back to Contents","Data 1: U.S. Refinery and Blender Net Production" "Sourcekey","MTTRPUS1","MLPRPUS1","METRPUS1","MENRPUS1","MEYRPUS1","MPRRPUS1","MPARP_NUS_1","MPLRPUS1","MBNRPUS1","MBURPUS1","MBYRPUS1","MBIRPUS1","MIIRPUS1","MIYRPUS1","MGFRPUS1","MGRRPUS1","MG1RP_NUS_1","M_EPM0RO_YPR_NUS_MBBL","MG4RP_NUS_1","MG5RP_NUS_1","M_EPM0CAL55_YPR_NUS_MBBL","M_EPM0CAG55_YPR_NUS_MBBL","MG6RP_NUS_1","MGARPUS1","MKJRPUS1","MKERPUS1","MDIRPUS1","MD0RP_NUS_1","MD1RP_NUS_1","MDGRPUS1","MRERPUS1","MRLRPUS1","MRMRPUS1","MRGRPUS1","MPCRPUS1","MNFRPUS1","MOTRPUS1","MNSRPUS1","MLURPUS1","MWXRPUS1","MCKRPUS1","MCMRPUS1","MCORPUS1","MAPRPUS1","MSGRPUS1","MMSRPUS1","MPGRPUS1"

209

Workbook Contents  

U.S. Energy Information Administration (EIA) Indexed Site

Monthly","9/2013","1/15/1936" Monthly","9/2013","1/15/1936" ,"Release Date:","11/27/2013" ,"Next Release Date:","Last Week of December 2013" ,"Excel File Name:","pet_pnp_refp_dc_nus_mbbl_m.xls" ,"Available from Web Page:","http://www.eia.gov/dnav/pet/pet_pnp_refp_dc_nus_mbbl_m.htm" ,"Source:","Energy Information Administration" ,"For Help, Contact:","infoctr@eia.gov" ,,"(202) 586-8800",,,"11/25/2013 11:25:41 AM" "Back to Contents","Data 1: U.S. Refinery and Blender Net Production" "Sourcekey","MTTRPUS1","MLPRPUS1","METRPUS1","MENRPUS1","MEYRPUS1","MPRRPUS1","MPARP_NUS_1","MPLRPUS1","MBNRPUS1","MBURPUS1","MBYRPUS1","MBIRPUS1","MIIRPUS1","MIYRPUS1","MGFRPUS1","MGRRPUS1","MG1RP_NUS_1","M_EPM0RO_YPR_NUS_MBBL","MG4RP_NUS_1","MG5RP_NUS_1","M_EPM0CAL55_YPR_NUS_MBBL","M_EPM0CAG55_YPR_NUS_MBBL","MG6RP_NUS_1","MGARPUS1","MKJRPUS1","MKERPUS1","MDIRPUS1","MD0RP_NUS_1","MD1RP_NUS_1","MDGRPUS1","MRERPUS1","MRLRPUS1","MRMRPUS1","MRGRPUS1","MPCRPUS1","MNFRPUS1","MOTRPUS1","MNSRPUS1","MLURPUS1","MWXRPUS1","MCKRPUS1","MCMRPUS1","MCORPUS1","MAPRPUS1","MSGRPUS1","MMSRPUS1","MPGRPUS1"

210

A Solution NMR Investigation into the Murine Amelogenin Splice-Variant LRAP (Leucine-Rich Amelogenin Protein).  

Science Conference Proceedings (OSTI)

Amelogenins are the dominant proteins present in ameloblasts during the early stages of enamel biomineralization, making up >90% of the matrix protein. Along with the full-length protein there are several splice-variant isoforms of amelogenin present including LRAP (Leucine-Rich Amelogenin Protein), a protein that consists of the first 33 and the last 26 residues of full-length amelogenin. Using solution-state NMR spectroscopy we have assigned the 1H-15N HSQC spectrum of murine LRAP (rp(H)LRAP) in 2% acetic acid at pH 3.0 by making extensive use of previous chemical shift assignments for full-length murine amelogenin (rp(H)M180). This correlation was possible because LRAP, like the full-length protein, is intrinsically disordered under these solution conditions. The major difference between the 1H-15N HSQC spectra of rp(H)M180 and rp(H)LRAP was an additional set of amide resonances for each of the seven non-proline residues between S12* and Y12 at the N-terminus of rp(H)LRAP indicating that the N-terminal region of LRAP exists in two different conformations. Analysis of the proline carbon chemical shifts suggest that the molecular basis for the two states is not a cis-trans isomerization of one or more of the proline residues in the N-terminal region and is likely due to a slow exchange process. As observed with rp(H)M180, residue specific changes in molecular dynamics, manifested by the reduction in intensity and disappearance of 1H-15N HSQC cross peaks, were observed with the addition of NaCl to rp(H)LRAP. These perturbations may signal early events governing supramolecular self-assembly of rp(H)LRAP into nanospheres. However, the different pattern of 1H-15N HSQC cross peak perturbation between rp(H)LRAP and rp(H)M180 in high salt suggest that the termini may behave differently in their respective nanospheres, and perhaps, these differences account for the cell signaling properties attributable to LRAP but not the full-length protein.

Buchko, Garry W.; Tarasevich, Barbara J.; Roberts, Jacky; Snead, Malcolm L.; Shaw, Wendy J.

2010-09-01T23:59:59.000Z

211

Long-Term Follow-Up of a Prospective Trial of Trimodality Therapy of Weekly Paclitaxel, Radiation, and Androgen Deprivation in High-Risk Prostate Cancer With or Without Prior Prostatectomy  

SciTech Connect

Purpose: Weekly paclitaxel, concurrent radiation, and androgen deprivation (ADT) were evaluated in patients with high-risk prostate cancer (PC) with or without prior prostatectomy (RP). Methods and Materials: Eligible post-RP patients included: pathological T3 disease, or rising prostate-specific antigen (PSA) {>=}0.5 ng/mL post-RP. Eligible locally advanced PC (LAPC) patients included: 1) cT2b-4N0N+, M0; 2) Gleason score (GS) 8-10; 3) GS 7 + PSA 10-20 ng/mL; or 4) PSA 20-150 ng/mL. Treatment included ADT (4 or 24 months), weekly paclitaxel (40, 50, or 60 mg/m{sup 2}/wk), and pelvic radiation therapy (total dose: RP = 64.8 Gy; LAPC = 70.2 Gy). Results: Fifty-nine patients were enrolled (LAPC, n = 29; RP, n = 30; ADT 4 months, n = 29; 24 months, n = 30; whites n = 29, African Americans [AA], n = 28). Baseline characteristics (median [range]) were: age 67 (45-86 years), PSA 5.9 (0.1-92.1 ng/mL), GS 8 (6-9). At escalating doses of paclitaxel, 99%, 98%, and 95% of doses were given with radiation and ADT, respectively, with dose modifications required primarily in RP patients. No acute Grade 4 toxicities occurred. Grade 3 toxicities were diarrhea 15%, urinary urgency/incontinence 10%, tenesmus 5%, and leukopenia 3%. Median follow-up was 75.3 months (95% CI: 66.8-82.3). Biochemical progression occurred in 24 (41%) patients and clinical progression in 11 (19%) patients. The 5- and 7-year OS rates were 83% and 67%. There were no differences in OS between RP and LAPC, 4- and 24-month ADT, white and AA patient categories. Conclusions: In addition to LAPC, to our knowledge, this is the first study to evaluate concurrent chemoradiation with ADT in high-risk RP patients. With a median follow-up of 75.3 months, this trial also represents the longest follow-up of patients treated with taxane-based chemotherapy with EBRT in high-risk prostate cancer. Concurrent ADT, radiation, and weekly paclitaxel at 40 mg/m{sup 2}/week in RP patients and 60 mg/m{sup 2}/week in LAPC patients is feasible and well-tolerated.

Hussain, Arif, E-mail: ahussain@som.umaryland.edu [University of Maryland Greenebaum Cancer Center, Baltimore, MD (United States); Department of Medicine, University of Maryland School of Medicine, Baltimore, MD (United States); Baltimore VA Medical Center, Baltimore, MD (United States); Wu, Yin [Department of Medicine, University of Maryland School of Medicine, Baltimore, MD (United States); Mirmiran, Alireza [Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD (United States); DiBiase, Steven [Cooper University Hospital, Camden, NJ (United States); Goloubeva, Olga [University of Maryland Greenebaum Cancer Center, Baltimore, MD (United States); Bridges, Benjamin [University of Maryland Greenebaum Cancer Center, Baltimore, MD (United States); Department of Medicine, University of Maryland School of Medicine, Baltimore, MD (United States); Mannuel, Heather [University of Maryland Greenebaum Cancer Center, Baltimore, MD (United States); Department of Medicine, University of Maryland School of Medicine, Baltimore, MD (United States); Baltimore VA Medical Center, Baltimore, MD (United States); Engstrom, Christine [Baltimore VA Medical Center, Baltimore, MD (United States); Dawson, Nancy [Lombardi Cancer Center, Georgetown University, Washington, D.C (United States); Amin, Pradip; Kwok, Young [Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD (United States)

2012-01-01T23:59:59.000Z

212

EVALUATION OF SPRING OPERATED RELIEF VALVE MAINTENANCE INTERVALS AND EXTENSION OF MAINTENANCE TIMES USING A WEIBULL ANALYSIS WITH MODIFIED BAYESIAN UPDATING  

Science Conference Proceedings (OSTI)

The Savannah River Site (SRS) spring operated pressure relief valve (SORV) maintenance intervals were evaluated using an approach provided by the American Petroleum Institute (API RP 581) for risk-based inspection technology (RBI). In addition, the impact of extending the inspection schedule was evaluated using Monte Carlo Simulation (MCS). The API RP 581 approach is characterized as a Weibull analysis with modified Bayesian updating provided by SRS SORV proof testing experience. Initial Weibull parameter estimates were updated as per SRS's historical proof test records contained in the Center for Chemical Process Safety (CCPS) Process Equipment Reliability Database (PERD). The API RP 581 methodology was used to estimate the SORV's probability of failing on demand (PFD), and the annual expected risk. The API RP 581 methodology indicates that the current SRS maintenance plan is conservative. Cost savings may be attained in certain mild service applications that present low PFD and overall risk. Current practices are reviewed and recommendations are made for extending inspection intervals. The paper gives an illustration of the inspection costs versus the associated risks by using API RP 581 Risk Based Inspection (RBI) Technology. A cost effective maintenance frequency balancing both financial risk and inspection cost is demonstrated.

Harris, S.; Gross, R.; Mitchell, E.

2011-01-18T23:59:59.000Z

213

Evaluation of oxygen utilization as an indicator of municipal solid-waste compost stability  

Science Conference Proceedings (OSTI)

This research evaluated oxygen utilization parameters as indicators of MSW compost stability. Parameters evaluated were the oxygen utilization rate (OUR), specific oxygen uptake rate (SOUR), five-day biochemical oxygen demand, and chemical oxygen demand. In addition, other suggested indicators of stability were investigated including percent volatile solids, volatile solids reduction, nitrogen content, carbon: nitrogen ratio, and reheating potential (RP). OUR is a measure of the rate of oxygen utilization by the microorganisms in the decomposition of organic matter in compost. OUR was observed to be sensitive to the degree of stabilization and decreased with increasing compost age and stability. OUR values near zero indicate that the compost microorganisms are in a state of endogenous respiration, which is characteristic of a stable compost. Therefore, OUR is an excellent indicator of stability. A number of disadvantages are associated with OUR for practical application. Therefore, other parameters were evaluated as indicators of stability based on their statistical correlation to OUR. RP exhibited the strongest correlation to OUR. In combination, RP and SOUR were the two parameters which exhibited the strongest correlation to OUR. OUR, RP, and SOUR are all measures of microbial activity which reflect the degree of organic decomposition, and therefore, stability. Based on the results of this research; OUR, RP, and SOUR are useful parameters in assessing compost stability.

Zimmerman, R.A.

1991-01-01T23:59:59.000Z

214

Selective Removal of Photoreceptor Cells In Vivo Using the Biodegradable Elastomer Poly(Glycerol Sebacate)  

E-Print Network (OSTI)

Retinal transplantation experiments have advanced considerably during recent years, but remaining diseased photoreceptor cells in the host retina physically obstruct the development of grafthost neuronal contacts that are ...

Ghosh, Fredrik

215

In vivo operation of the Boston 15-channel wireless subretinal visual prosthesis  

E-Print Network (OSTI)

This presentation concerns the engineering development of the Boston visual prosthesis for restoring useful vision to patients blind with degenerative retinal disease. A miniaturized, hermetically-encased, 15-channel ...

Wyatt, John L.

216

Readiness Assessment for MF-628 Drum Treatment Facility - Advanced Mixed Waste Treatment Project … 5-07  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

RADIATION PROTECTION (RP) RADIATION PROTECTION (RP) Objective: RP.1 Adequate and correct contamination control procedures and safety limits are in place for operating the DTF ventilation system and conducting drum treatment operations in the DTF. (CR1, CR10) a. A thorough hazard analysis addressing contamination control and radiation protection has been completed for drum treatment activities in the DTF. b. The design of the DTF and ventilation system is adequate to prevent the spread of contamination. The adequacy has been demonstrated by testing and mockup operations. c. Appropriate limits, contamination control methods, and radiation protection practices have been identified and included in the applicable AMOW, PTW and procedures. d. Adequate radiation monitoring instruments are installed and properly located

217

Microsoft Word - 2013-07-11_ESF Mission Report_Revision 0  

NLE Websites -- All DOE Office Websites (Extended Search)

RP-2013-00303 RP-2013-00303 EPA/600/R-13/135 Revision 0 REPORT OF THE UNITED STATES EMBASSY SCIENCE FELLOWS SUPPORT TO THE GOVERNMENT OF JAPAN - MINISTRY OF THE ENVIRONMENT OBSERVATIONS AND COMMENTARY ON REMEDIATION OF THE LANDS OFF-SITE FROM THE FUKUSHIMA DAIICHI REACTORS Mission dates: 4 February - 29 March 2013 JULY 2013 REPORT APPROVED for Release for Unlimited (Release to Public) SRNL-RP-2013-00303 EPA/600/R-13/135 Revision 0 Page 2 of 133 DISCLAIMERS This work was prepared under an agreement with and funded by the U.S. Government. Neither the U.S. Government or its employees, nor any of its contractors, subcontractors or their employees, makes any express or implied:

218

INDUSTRIAL SAFETY & HEALTH (ISH)  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

RADIATION PROTECTION (RP) RADIATION PROTECTION (RP) OBJECTIVE RP.1 The TA-55 SST Facility has a radiation protection program in-place to ensure adequate radiation protection for the worker and the public. (Core Requirements 2, 8, 11) Criteria 1. Radiation exposure to workers and the public is minimized through implementation of the as low as reasonably achievable (ALARA) concept and radiological work permits (RWPs). 2. The generation and spread of radioactive contamination is minimized through radioactive contamination control, radioactive effluent control, and RWPs 3. A radiological control technician (RCT) will oversee operations that involve handling storage containers and provide radiation protection support, as required. 4. Radiation monitoring will be provided when appropriate. An RCT will determine

219

WORLD OIL SUPPLY PRODUCTION, RESERVES, AND EOR  

E-Print Network (OSTI)

The weakness of intelligence is in discerning the turning points (J. Schlesinger: former CIA Director and Ex-Secretary of Defense and of Energy) World Oil Consumption: Since 1980, the world has consumed far more oil than has been discovered. We are now finding only one barrel of new oil for every four barrels that we consume. As Donald Hodel, Ex-U.S. Secretary of Energy said: We are sleepwalking into a disaster. Global R/P: (Figure 1-A). Economists and laymen routinely view the future of global oil production as being directly related to a simple global Reserves/Production (R/P) ratio. This implies that oil produced in all of the worlds fields will abruptly stop when the R/P date (40 years in the future) is reached. This is as unrealistic as to expect all humans to die off suddenly, instead of gradually. Global R/Ps should NOT be used to estimate timing of future oil supplies. National R/P: (Figure 1-B). Instead of posting one average Global R/P of 40 years for the entire world, Figure 1-B shows (National R/P) for individual nations. This results in a very different, but a much more realistic semi-quantitative picture of the distribution of the worlds claimed oil reserves and future global oil supply than does Figure 1-A. Scale: All of these graphs are drawn to scale, which puts tight limits on their construction and analysis. A 40,000-million-barrels (4 BBO/year x 10 years) rectangle in the upper left corner of each figure shows the graphic scale for the area under the World Production Curve (WPC). (BBO =

M. King; Hubbert Center; M. King; Hubbert Center; L. F. Ivanhoe

2000-01-01T23:59:59.000Z

220

Surveillance Guide - ERS ERS 14.2 Emmissions Monitoring  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

EMISSIONS MONITORING EMISSIONS MONITORING 1.0 Objective The objective of this surveillance is to verify that the contractor is monitoring emissions of radioactive materials and chemicals. The Facility Representative will verify operability of equipment and examine implementation of procedures and processes for collecting, analyzing and recording data. The Facility Representative evaluates compliance with applicable requirements from DOE and implementation of appropriate codes and standards. 2.0 References 2.1 DOE 5400.5, Radiation Protection of the Public and the Environment 3.0 Requirements Implemented This surveillance implements requirements RP-0028 and ER-0023 from the RL S/RIDs. Requirement RP-0028 relates to oversight of

Note: This page contains sample records for the topic "retinitis pigmentosa rp" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


221

The New Reid Hospital and Health Care Services Physical Plant: An Analysis of Prospective Roles for Richmond Power & Light in Plant Privatization  

Science Conference Proceedings (OSTI)

Richmond Power & Light Company (RP&L) is a community-owned electric utility serving the City of Richmond, Indiana, and other customers. As the largest municipal utility in Indiana, RP&L maintains a keen focus on and strong commitment to the health and vitality of the community it serves. Reid Hospital and Healthcare Services (Reid), the facility that provides health care to Richmond and the surrounding community, is planning the construction of a new health care center to replace the current facility. Li...

2004-06-15T23:59:59.000Z

222

Predicting Radiation Pneumonitis After Stereotactic Ablative Radiation Therapy in Patients Previously Treated With Conventional Thoracic Radiation Therapy  

SciTech Connect

Purpose: To determine the incidence of and risk factors for radiation pneumonitis (RP) after stereotactic ablative radiation therapy (SABR) to the lung in patients who had previously undergone conventional thoracic radiation therapy. Methods and Materials: Seventy-two patients who had previously received conventionally fractionated radiation therapy to the thorax were treated with SABR (50 Gy in 4 fractions) for recurrent disease or secondary parenchymal lung cancer (T <4 cm, N0, M0, or Mx). Severe (grade {>=}3) RP and potential predictive factors were analyzed by univariate and multivariate logistic regression analyses. A scoring system was established to predict the risk of RP. Results: At a median follow-up time of 16 months after SABR (range, 4-56 months), 15 patients had severe RP (14 [18.9%] grade 3 and 1 [1.4%] grade 5) and 1 patient (1.4%) had a local recurrence. In univariate analyses, Eastern Cooperative Oncology Group performance status (ECOG PS) before SABR, forced expiratory volume in 1 second (FEV1), and previous planning target volume (PTV) location were associated with the incidence of severe RP. The V{sub 10} and mean lung dose (MLD) of the previous plan and the V{sub 10}-V{sub 40} and MLD of the composite plan were also related to RP. Multivariate analysis revealed that ECOG PS scores of 2-3 before SABR (P=.009), FEV1 {<=}65% before SABR (P=.012), V{sub 20} {>=}30% of the composite plan (P=.021), and an initial PTV in the bilateral mediastinum (P=.025) were all associated with RP. Conclusions: We found that severe RP was relatively common, occurring in 20.8% of patients, and could be predicted by an ECOG PS score of 2-3, an FEV1 {<=}65%, a previous PTV spanning the bilateral mediastinum, and V{sub 20} {>=}30% on composite (previous RT+SABR) plans. Prospective studies are needed to validate these predictors and the scoring system on which they are based.

Liu Hui; Zhang Xu [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Vinogradskiy, Yevgeniy Y. [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Swisher, Stephen G. [Department of Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [Department of Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Komaki, Ritsuko [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Chang, Joe Y., E-mail: jychang@mdanderson.org [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States)

2012-11-15T23:59:59.000Z

223

Computer Simulation of Scale Formation  

DOE Green Energy (OSTI)

This paper summarizes results of recent analyses performed by Battelle-Northwest in EPRI project RP 653-3: Computer Simulation of Scaling in Geothermal Systems. The results reported here are drawn primarily from case evaluations performed over the 12 months since the preceding EPRI Geothermal Symposium held in Monterey in June 1979. The present project is a continuation of a previous project designated RP 653-1. The ultimate objective of research performed in this project is to develop analytical tools (computer codes) and the supporting thermophysical and chemical data base that can be used to predict scaling and corrosion in geothermal power generating systems.

Lessor, D.L.; Kreid, D.K.

1980-12-01T23:59:59.000Z

224

Operational Radiation Protection in High-Energy Physics Accelerators  

SciTech Connect

An overview of operational radiation protection (RP) policies and practices at high-energy electron and proton accelerators used for physics research is presented. The different radiation fields and hazards typical of these facilities are described, as well as access control and radiation control systems. The implementation of an operational RP programme is illustrated, covering area and personnel classification and monitoring, radiation surveys, radiological environmental protection, management of induced radioactivity, radiological work planning and control, management of radioactive materials and wastes, facility dismantling and decommissioning, instrumentation and training.

Rokni, S.H.; Fasso, A.; Liu, J.C.; /SLAC

2012-04-03T23:59:59.000Z

225

RAC Report No. 3-CDC-Task Order 7-2000-FINAL FINAL REPORT  

E-Print Network (OSTI)

.S. Environmental Protection Agency GE-VNC General Electric ­ Vallecitos Nuclear Center Hanford-RL Hanford Richland (Hanford) Richland RP (Hanford Office of) River Protection SQS Small Quantity Site SRS Savannah River Site Report WIPP Waste Isolation Pilot Plant WM Waste Material WMP Waste Material Parameter WSDT Working Site

226

CERTIFICATION OF WASTE GENERATOR SITES 2009 EPA WIPP RECERTIFICATION FACT SHEET United States Environmental Protection Agency | Office of Air and Radiation (6608J) | June 2009  

E-Print Network (OSTI)

to a linear program: minimized, (p,p )B iRp,p wi,p,p |i,p - i,p | subject to dp = nT p K-1 qii,p , (i, p) dfloor = c , (10) where wi,p,p = p,p K-1 qi 2. For fixed d, and Q, we can maximize over in closed form

227

2005 EPA WIPP RECERTIFICATION GROUNDWATER AT WIPP FACT SHEET No. 5  

E-Print Network (OSTI)

aspects of envisaged WIPP operations involving shielded containers. We are submitting this information so in the document. Nuclear Safety Assessment of Shielded Containers in the WIPP System of Operations The WTS Nuclear accidents considered in the WIPP Documented CBFO:AMO:RP:KJB:08-1419:UFC5486 #12;Jonathan Edwards -2 Safety

228

Compendium of Resource Equivalency Analyses: New Carissa Oil Spill References  

E-Print Network (OSTI)

University Press. Stanford, California. Ainley, D.G., R.P. Henderson, and C.S. Strong. 1990c. Leachs Storm-Petrel and Ashy Storm-Petrel, pages 128-162 in Seabirds of the Farallon Islands (D.G. Ainley and R.J. Boekelheide, eds.). Stanford University Press. Stanford, California.

D. N. Nettleship; H. R. Carter; R. J. Boekelheide; S. H. Morrell; C. S. Strong; Pages In; S. H. Morrell; R. J. Boekelheide; Rhinoceros Auklet; Tufted Puffin; N. Nur; Marbled Murrelet; Wildlife Service; Recovery Plan

2005-01-01T23:59:59.000Z

229

"!# $&%(')0' 1324 5 4768)9@ AB!C6A9760806 'D' EFHGD8A9IQP CRH'D  

E-Print Network (OSTI)

$PyD&HxoD$r5H)H$notpµpo8$¯«oup¯pnzC $oRps$noRqoD$nuoR«oRSzpt`vu #pxoD&%$so y $U"op²pow&g$ y{ 9IHI(o¤xe9oRp2QH

Paris-Sud XI, Université de

230

VOLUME 16, NUMBER 3 HVAC&R RESEARCH MAY 2010 The Effects of Filtration on  

E-Print Network (OSTI)

VOLUME 16, NUMBER 3 HVAC&R RESEARCH MAY 2010 273 The Effects of Filtration on Pressure Drop and Energy Consumption in Residential HVAC Systems (RP-1299) Brent Stephens Atila Novoselac, PhD Jeffrey A of high-efficiency HVAC filters is a common strategy to control exposure to airborne particulate matter

Siegel, Jeffrey

231

Determining Long-Term Performance of Cool Storage Systems from Short-Term Tests; Literature Review, Preliminary Methodology Description, and Final Site Selection (Final Revision of Nov. 1997 Report)  

E-Print Network (OSTI)

This preliminary report contains the literature review, a preliminary description of the methodologies that have been chosen for the project and final site selection recommendations for ASHRAE Research Project RP 1004 ~ "Determining Long-term Performance of Cool Storage Systems From Short-term Tests".

Reddy, T. A.; Elleson, J.; Haberl, J. S.; Claridge, D. E.

1998-01-01T23:59:59.000Z

232

Original article Epistatic interaction  

E-Print Network (OSTI)

,elanogaster were screened for chromosome inversions and 23 paracentric inversions including 4 common cosmopolitan (In(2L)t, In(2R)NS, In(3L)P and In(3R)P), 2 rare cosmopolitan (In(3R)Mo and In(3R)C) and a recurrent

Recanati, Catherine

233

Contra Costa Santa Clara  

E-Print Network (OSTI)

Power Plant Watson Cogen Sentinel Energy Project Peaker Hydrogen Energy California Abengoa Mojave Solar 1 Palen Solar Power Project Beacon Solar Energy Ridgecrest Solar Power Project El Centro Unit 3 (RP) ON HOLD Pastoria Expan. Project (Pastoria2) (E) ON HOLD Rice Solar Energy Project GWF Hanford Combined

234

Kheshbn No. 125- Spring 1995 - Journal  

E-Print Network (OSTI)

IIK on H 711K o'B H ^ ]anp ]IK paayn ^nv 7? am ,p"nryaoKoPR ORI /|" lyr? nyn oyn anp nyi ? 03U GTR11 TDTlRll - R m (1947 pa) "Q-IR lyrpR puya anp pijn pR ,iiRp-iRa pR ,ya

1995-01-01T23:59:59.000Z

235

Earth Energy Resources Inc. 2010 ICSE CONFERENCE, April 28, 2010 FORWARD LOOKING STATEMENTS  

E-Print Network (OSTI)

. ­ 2010 ICSE CONFERENCE, April 28, 2010 USA'S CONVENTIONAL CRUDE OIL STATISTICS · Perspective... · Proven · Reserves to Production ratio (R/P) equaled 11.26 years in 2007 · Daily 2010 US oil consumptio, market and business conditions; the volatility of oil and gas prices; production and development costs

Utah, University of

236

Platform effects on optical variability and prediction of underwater visibility  

E-Print Network (OSTI)

Platform effects on optical variability and prediction of underwater visibility Grace Chang,1, specifically the breakdown of stratification from mixing by the hull of R/P FLIP. Modeled underwater radiance Successful, rapid identification of underwater tar- gets and accurate underwater imaging are critical

You, Yu

237

FUEL CELL SYSTEM ECONOMICS: COMPARING THE COSTS OF GENERATING POWER WITH STATIONARY  

E-Print Network (OSTI)

during many months of the year). * Similarly, use of PEM fuel cell waste heat for hot water heating wouldFUEL CELL SYSTEM ECONOMICS: COMPARING THE COSTS OF GENERATING POWER WITH STATIONARY AND MOTOR VEHICLE PEM FUEL CELL SYSTEMS UCD-ITS-RP-04-21 April 2004 by Timothy Lipman University of California

Kammen, Daniel M.

238

A CAD system for heterogeneous solid modelling  

Science Conference Proceedings (OSTI)

Objects that are made up of multiple materials and known as heterogeneous objects are now increasingly being used in engineering applications. The development of new fabrication methods like rapid prototyping (RP), calls for new techniques to ... Keywords: CAD model, STL file, functionally graded material, geometric information, heterogeneous models, heterogeneous solids, layered manufacturing, manufacturing strategy, material information, rapid prototyping, solid modelling

Puneet Tandon; Anuj Kant

2005-11-01T23:59:59.000Z

239

Aerial Observations of Hawaii's Wake  

Science Conference Proceedings (OSTI)

Under the influence of the east-northeasterly trade winds, the island of Hawaii generates a wake that extends about 200 km to the west-southwest. During the HaRP project in July and August 1990, five wake surveys were carried out by the NCAR ...

Ronald B. Smith; Vanda Grubii?

1993-11-01T23:59:59.000Z

240

Validation of the self-completed Cambridge-Hopkins questionnaire (CH-RLSq) for ascertainment of restless legs syndrome (RLS) in a population survey  

E-Print Network (OSTI)

2004;164(2):196202. [5] Allen RP, Walters AS, Montplaisir J, Hening W, Myers A, Bell TJ, et al. Restless legs syndrome prevalence and impact: REST general population study. Arch Intern Med 2005;165(11):128692. [6] Altman DG, Bland JM. Diagnostic tests...

Burchell, Brendan J.; Allen, Richard P.; MacDonald, Ben; Hening, Wayne A.; Earley, Christopher J.

2008-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "retinitis pigmentosa rp" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


241

RLS and blood donation  

E-Print Network (OSTI)

, Luedemann J, Trenkwalder C, John U, Kessler C. Sex and the risk of restless legs syndrome in the general population. Arch Intern Med 2004;164(2):196202. [9] Allen RP, Walters AS, Montplaisir J, Hening W, Myers A, Bell TJ, et al. Restless legs syndrome...

Burchell, Brendan J.; Allen, Richard P.; Miller, Jessica K.; Hening, Wayne A.; Earley, Christopher J.

2009-01-01T23:59:59.000Z

242

Wave-coherent airflow and critical layers over ocean waves  

Science Conference Proceedings (OSTI)

An analysis of coherent measurements of winds and waves from data collected during the ONR HiRes program from R/P FLIP off the coast of northern California in June 2010 is presented. A suite of wind and wave measuring systems was deployed to ...

Laurent Grare; Luc Lenain; W. Kendall Melville

243

Lab 3 -Equivalent Inertia In this problem, we will nd the equation of motion for the haptic paddle and determine the equivalent mass,  

E-Print Network (OSTI)

triangle, * handle * small stand * big stand for the motor hall e ect sensor stand 0.5" cube magnet mount 0 from the string on the sector pulley to the center of rotation. rp is the radius of the motor pulley. The sector pulley handle has a mass m. There is an applied torque Tm from the motor on the motor pulley

Stanford University

244

A GIS tool for modelling annual diffuse infiltration on a plot scale  

Science Conference Proceedings (OSTI)

ArcB is a GIS tool for modelling annual diffuse infiltration (R"P) from precipitation (P) on a plot scale that uses ArcObjects as the programming language to incorporate equations and boundary conditions for the water-balance consistency. Because detailed ... Keywords: ArcObjects, Diffuse infiltration, GIS, SE Spain, Semiarid climate

Salvador EspaA, Francisco J. Alcal, Ngela Vallejos, Antonio Pulido-Bosch

2013-04-01T23:59:59.000Z

245

Kheshbn No. 135 - Spring 2000 - Journal  

E-Print Network (OSTI)

ypHJKJRaRi mn pynx n fryts poRns .paaV?" snyn yonna pRp*a .pix ypnnytrm TX T porn .ajxa ]nyay ]toa px p am -|8 ^tai &xa a pyn nrp D"a ,porn px ypxa pxnaya px pxpya

2000-01-01T23:59:59.000Z

246

The ribosomal protein genes and Minuteloci of Drosophila melanogaster  

E-Print Network (OSTI)

necessary, D. mela- nogaster genes were named or renamed according to the standard metazoan RP gene nomenclature proposed by Wool and colleagues [5,58,59] and approved by the HUGO Gene Nomenclature Committee [18], whilst still conforming to Fly- Base [60...

Marygold, Steven J; Roote, John; Reuter, Gunter; Lambertsson, Andrew; Ashburner, Michael; Millburn, Gillian; Harrison, Paul; Yu, Zhan; Kenmochi, Naoya; Kaufman, Thomas C; Leevers, Sally J; Cook, Kevin R

2007-10-10T23:59:59.000Z

247

BWR Source Term Reduction - Estimating Cobalt Transport to the Reactor  

Science Conference Proceedings (OSTI)

The NEI/EPRI/INPO RP 2020 Initiative gave EPRI the task of reducing industry radiation fields. EPRIs approach includes developing an understanding of the fundamentals of activity transport and deposition, and benchmarking industry data to these theoretical mechanisms to determine the most effective methods for BWR radiation field reduction.

2008-11-26T23:59:59.000Z

248

If Youre So Smart, Why Arent You the Boss? Explaining the Persistent Vertical Gender Gap in Management  

E-Print Network (OSTI)

to Women, 1970-71 to 2008-09 Fo rP ee rR ev iew Business BAsAll BAs MBAs Source: Digest of Education Statistics 2011,9 percent er of business BAs and 4 percent of MBAs in 1970-

Haveman, Heather A.; Beresford, Lauren S.

2011-01-01T23:59:59.000Z

249

WIPP Waste Information System Waste Container Data Report  

E-Print Network (OSTI)

WIPP Waste Information System Waste Container Data Report 06/06/2008 07:50 2.6 % LASB00411 % % Report Date Run by Report Site Id Container Number Waste Stream Data Status Code PEARCYM Version RP0360 Selection Criteria - Total Pages PRD02Instance 5 #12;Waste Isolation Pilot Plant Waste Container Data Report

250

WIPP Waste Information System Waste Container Data Report  

E-Print Network (OSTI)

WIPP Waste Information System Waste Container Data Report 06/06/2008 07:49 2.6 % LAS817174 % % Report Date Run by Report Site Id Container Number Waste Stream Data Status Code PEARCYM Version RP0360 Selection Criteria - Total Pages PRD02Instance 5 #12;Waste Isolation Pilot Plant Waste Container Data Report

251

Microsoft Word - EM Major Contracts Summary 022713update.docx  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

DE-AC07-05ID14516 32305-93015 3.585B Idaho Cleanup Project Cost plus incentive fee Idaho Treatment Group DE-RP07-091D14813 101111-93015 417M Advanced Mixed Waste...

252

Texas Tech University Energy Savings Program April 2011 Update  

E-Print Network (OSTI)

is being submitted in accordance with Governor's Executive Order RP 49, Electric Conservation by State to the same time period for FY 10. Gas usage is down 7.9% due to the increased quantity of cogeneration steam is especially significant since average low temperatures for January and February were 3 and 4 degrees lower

Gelfond, Michael

253

Baseline Risk Assessment for the F-Area Burning/Rubble Pits and Rubble Pit  

SciTech Connect

This document provides an overview of the Savannah River Site (SRS) and a description of the F-Area Burning/Rubble Pits (BRPs) and Rubble Pit (RP) unit. It also describes the objectives and scope of the baseline risk assessment (BRA).

Palmer, E. [Westinghouse Savannah River Company, AIKEN, SC (United States)

1996-03-01T23:59:59.000Z

254

The Impact of Trade Wind Strength on Precipitation over the Windward Side of the Island of Hawaii  

Science Conference Proceedings (OSTI)

The effects of trade wind strength and the diurnal heating cycle on the production of summer trade wind rainfall on the windward side of the island of Hawaii are examined from the data collected from the Hawaiian Rainband Project (HaRP) during 11 ...

Mary Ann Esteban; Yi-Leng Chen

2008-03-01T23:59:59.000Z

255

Coal pyrolysis for utility use: Final report  

SciTech Connect

EPRI undertook an extensive research effort to evaluate the viability of coal pyrolysis products for utility use. The objectives of the studies were to evaluate the combustion and storage characteristics of pyrolysis char and to evaluate the upgrading potential of pyrolysis liquid products (tar). To achieve these objectives, it was necessary to produce sufficient quantities of the char and tar in a process unit large enough to produce commercially representative products. For both technical and availability reasons, EPRI selected the Lurgi-Ruhrgas (L-R) process for the production run (under subcontract to Bechtel Group, Inc. RP2505-2). Several contractors were to do the liquid upgrading. Two contractors were selected to use alternative processes for upgrading the L-R heavy tar: Lummus-Crest, Inc. (RP2505-5), using its LC-fining technology, and Veba Oel (RP2505-6), using its Combi-Cracking process. (The Combi-Cracking process also simultaneously hydrotreats the coal-tar-derived distillates.) Universal Oil Products, Inc. (UOP) was selected to hydrotreat the light and middle oils from the L-R process (RP2505-7), as well as the distillable material produced by Lummus. Unfortunately, none of these contractors received the anticipated products. The light oil was in the form of a light oil-water emulsion and the middle oil had been blended with the solids-laden heavy oil during L-R operation. Combustion Engineering, Inc. carried out a two-phase program to evaluate the combustion characteristics of pyrolysis char (RP2505-4).

McKinsey, R.; Luebke, C.P.; Thelen, H.J.; ya Nsakala, N.; Riegel, H.

1987-07-01T23:59:59.000Z

256

Incorporating Single-nucleotide Polymorphisms Into the Lyman Model to Improve Prediction of Radiation Pneumonitis  

SciTech Connect

Purpose: To determine whether single-nucleotide polymorphisms (SNPs) in genes associated with DNA repair, cell cycle, transforming growth factor-{beta}, tumor necrosis factor and receptor, folic acid metabolism, and angiogenesis can significantly improve the fit of the Lyman-Kutcher-Burman (LKB) normal-tissue complication probability (NTCP) model of radiation pneumonitis (RP) risk among patients with non-small cell lung cancer (NSCLC). Methods and Materials: Sixteen SNPs from 10 different genes (XRCC1, XRCC3, APEX1, MDM2, TGF{beta}, TNF{alpha}, TNFR, MTHFR, MTRR, and VEGF) were genotyped in 141 NSCLC patients treated with definitive radiation therapy, with or without chemotherapy. The LKB model was used to estimate the risk of severe (grade {>=}3) RP as a function of mean lung dose (MLD), with SNPs and patient smoking status incorporated into the model as dose-modifying factors. Multivariate analyses were performed by adding significant factors to the MLD model in a forward stepwise procedure, with significance assessed using the likelihood-ratio test. Bootstrap analyses were used to assess the reproducibility of results under variations in the data. Results: Five SNPs were selected for inclusion in the multivariate NTCP model based on MLD alone. SNPs associated with an increased risk of severe RP were in genes for TGF{beta}, VEGF, TNF{alpha}, XRCC1 and APEX1. With smoking status included in the multivariate model, the SNPs significantly associated with increased risk of RP were in genes for TGF{beta}, VEGF, and XRCC3. Bootstrap analyses selected a median of 4 SNPs per model fit, with the 6 genes listed above selected most often. Conclusions: This study provides evidence that SNPs can significantly improve the predictive ability of the Lyman MLD model. With a small number of SNPs, it was possible to distinguish cohorts with >50% risk vs <10% risk of RP when they were exposed to high MLDs.

Tucker, Susan L., E-mail: sltucker@mdanderson.org [Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Li Minghuan [Department of Radiation Oncology, Shandong Cancer Hospital, Jinan, Shandong (China)] [Department of Radiation Oncology, Shandong Cancer Hospital, Jinan, Shandong (China); Xu Ting; Gomez, Daniel [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Yuan Xianglin [Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan (China)] [Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan (China); Yu Jinming [Department of Radiation Oncology, Shandong Cancer Hospital, Jinan, Shandong (China)] [Department of Radiation Oncology, Shandong Cancer Hospital, Jinan, Shandong (China); Liu Zhensheng; Yin Ming; Guan Xiaoxiang; Wang Lie; Wei Qingyi [Department of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [Department of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Mohan, Radhe [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Vinogradskiy, Yevgeniy [University of Colorado School of Medicine, Aurora, Colorado (United States)] [University of Colorado School of Medicine, Aurora, Colorado (United States); Martel, Mary [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Liao Zhongxing [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States)

2013-01-01T23:59:59.000Z

257

Minimization of Motion Smear: Reducing Avian Collision with Wind Turbines; Period of Performance: July 12, 1999 -- August 31, 2002  

Science Conference Proceedings (OSTI)

Collisions with wind turbines can be a problem for many species of birds. Of particular concern are collisions by eagles and other protected species. This research study used the laboratory methods of physiological optics, animal psychophysics, and retinal electrophysiology to analyze the causes of collisions and to evaluate visual deterrents based on the results of this analysis. Bird collisions with the seemingly slow-moving turbines seem paradoxical given the superb vision that most birds, especially raptors, possess. However, our optical analysis indicated that as the eye approaches the rotating blades, the retinal image of the blade (which is the information that is transmitted to the animal's brain) increases in velocity until it is moving so fast that the retina cannot keep up with it. At this point, the retinal image becomes a transparent blur that the bird probably interprets as a safe area to fly through, with disastrous consequences. This phenomenon is called"motion smear" or"motion blur."

Hodos, W.

2003-08-01T23:59:59.000Z

258

Lab Spotlight: Argonne National Laboratory  

NLE Websites -- All DOE Office Websites (Extended Search)

Lab Spotlight: Argonne National Laboratory Lab Spotlight: Argonne National Laboratory ultrananocrystalline diamond (UNCD) technology Researchers John Carlisle (left) and Orlando Auciello (right) are developing an ultrathin biocompatible coating for the device. Creating Diamond Coatings for the Retinal Implant Argonne National Laboratory (ANL) plays a critical role in the success of the electrode implants used in the Artificial Retina Project. That's where researchers Orlando Auciello and colleague John Carlisle are using their patented ultrananocrystalline diamond (UNCD) technology to apply a revolutionary new coating to the retinal prosthetic device. The new packaging promises to provide a very thin, ultrasmooth film that will be far more compact and biocompatible than the bulky materials used to encase

259

Health Insurance Portability and Accountability Act-Compliant Ocular Telehealth Network for the Remote Diagnosis and Management of Diabetic Retinopathy  

SciTech Connect

In this article, we present the design and implementation of a regional ocular telehealth network for remote assessment and management of diabetic retinopathy (DR), including the design requirements, network topology, protocol design, system work flow, graphics user interfaces, and performance evaluation. The Telemedical Retinal Image Analysis and Diagnosis Network is a computer-aided, image analysis telehealth paradigm for the diagnosis of DR and other retinal diseases using fundus images acquired from primary care end users delivering care to underserved patient populations in the mid-South and southeastern United States.

Li, Yaquin [University of Tennessee, Knoxville (UTK); Karnowski, Thomas Paul [ORNL; Tobin Jr, Kenneth William [ORNL; Giancardo, Luca [ORNL; Garg, Seema [University of North Carolina; Fox, Karen [Delta Health Alliance; Chaum, Edward [University of Tennessee, Knoxville (UTK)

2011-01-01T23:59:59.000Z

260

CYCLOPS: A mobile robotic platform for testing and validating image processing and autonomous navigation algorithms in support of artificial vision prostheses  

Science Conference Proceedings (OSTI)

While artificial vision prostheses are quickly becoming a reality, actual testing time with visual prosthesis carriers is at a premium. Moreover, it is helpful to have a more realistic functional approximation of a blind subject. Instead of a normal ... Keywords: Artificial vision prostheses, Autonomous navigation, Cloud computing, Image processing, Retinal implants, Robotics, Self-commanding, Tele-commanding, Worldwide accessibility

Wolfgang Fink; Mark A. Tarbell

2009-12-01T23:59:59.000Z

Note: This page contains sample records for the topic "retinitis pigmentosa rp" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


261

Schroedinger Eigenmaps for the Analysis of Bio-Medical Data  

E-Print Network (OSTI)

We introduce Schroedinger Eigenmaps, a new semi-supervised manifold learning and recovery technique. This method is based on an implementation of graph Schroedinger operators with appropriately constructed barrier potentials as carriers of labeled information. We apply it to analyze two complex bio-medical datasets: multispectral retinal images and microarray gene expressions.

Czaja, Wojciech

2011-01-01T23:59:59.000Z

262

A biologically inspired technique for sampling of color images  

Science Conference Proceedings (OSTI)

Color space dimensionality possesses main problem in fast processing of color images so appropriate sampling of color images is very important. Unlike the existing statistical sampling algorithm, in this paper, a biologically inspired non-linear color ... Keywords: Buchsbaum non-linearity, human retinal receptors, just noticeable difference (JND), model of color vision, non-linear sampling

Rajesh B Raut; K. M. Bhurchandi

2008-11-01T23:59:59.000Z

263

Introduction The retina is compartmentalized at the exter-  

E-Print Network (OSTI)

School of Medicine, Salt Lake City, UT 84132 Abstract Photoreceptor degenerations initiated in rods of novel ectopic microneuromas in the remnant inner nuclear layer (INL). Bipolar and amacrine cells engage regardless of the molecular defects that initially trigger retinal degenerations. Although remodeling may

Marc, Robert E.

264

Parameter estimation for ridge detection in images with thin structures  

Science Conference Proceedings (OSTI)

This paper presents an analysis of four ridge detectors in images with thin structures: plant root images and retinal images. Two proposed detectors and two detectors from the literature are used. We estimate the optimal parameters for each detector ... Keywords: parameter estimation, ridge detection

Talita Perciano; Roberto Hirata, Jr.; Lcio Andr De Castro Jorge

2010-11-01T23:59:59.000Z

265

Assortedfungi Mycol. Res. 3, 509547 (2007)  

E-Print Network (OSTI)

, surrounded by a lipid monolayer and immersed in oil (pictured below). When two droplets stick together solutions of different ions with channels in the connecting walls to pump the ions. This acted pump bacteriorhodopsin offered an electrochemical light-meter that mimics light-detecting retinal cells

Hibbett, David S.

266

http://mvr.mcgill.ca/Robert/ rhess_home.html  

E-Print Network (OSTI)

of luminances (left) and retinal illumination (right) found in the natural world Sun Fluorescent light/bulbs sensitivity functions at three different light levels Spatial Frequency (cycles/mm on retina) Spatial operating range but poor contrast sensitivity Relative light intensity Intensity Brightness Brightness Good

Hess, Robert F.

267

Automatic cup-to-disc ratio estimation using active contours and color clustering in fundus images for glaucoma diagnosis  

Science Conference Proceedings (OSTI)

In this paper we propose a new automatic technique for the segmentation of the Optic Disc (OD) and optic nerve head (cup) regions in retinographies for glaucoma diagnosis. It provides an estimation of the Cup-to-Disc Ratio, the main clinical indicator ... Keywords: K-means, cup-to-disc-ratio, glaucoma, retinal images

Irene Fondn; Francisco Nez; Mercedes Tirado; Soledad Jimnez; Pedro Alemany; Qaisar Abbas; Carmen Serrano; Begoa Acha

2012-06-01T23:59:59.000Z

268

Infrared retina  

DOE Patents (OSTI)

Exemplary embodiments provide an infrared (IR) retinal system and method for making and using the IR retinal system. The IR retinal system can include adaptive sensor elements, whose properties including, e.g., spectral response, signal-to-noise ratio, polarization, or amplitude can be tailored at pixel level by changing the applied bias voltage across the detector. "Color" imagery can be obtained from the IR retinal system by using a single focal plane array. The IR sensor elements can be spectrally, spatially and temporally adaptive using quantum-confined transitions in nanoscale quantum dots. The IR sensor elements can be used as building blocks of an infrared retina, similar to cones of human retina, and can be designed to work in the long-wave infrared portion of the electromagnetic spectrum ranging from about 8 .mu.m to about 12 .mu.m as well as the mid-wave portion ranging from about 3 .mu.m to about 5 .mu.m.

Krishna, Sanjay (Albuquerque, NM); Hayat, Majeed M. (Albuquerque, NM); Tyo, J. Scott (Tucson, AZ); Jang, Woo-Yong (Albuquerque, NM)

2011-12-06T23:59:59.000Z

269

Nonselective Losses in Foveal Chromatic and Luminance Sensitivity in Multiple Sclerosis  

E-Print Network (OSTI)

perimeter. To control the overall state of retinal ad- aptation of the subject, a circular white background (ElectroencephalogrClin Neurophysiol 56:16P, 1983). t Part of the work reported in this paper was carried out while thresholds for a sharp-edged, 1-deg spectral test flash presented on a large, bright (1000-Td) white

Foster, David H.

270

Quality Enhancement and Nerve Fibre Layer Artefacts Removal in Retina Fundus Images by Off Axis Imaging  

SciTech Connect

Retinal fundus images acquired with non-mydriatic digital fundus cameras are a versatile tool for the diagnosis of various retinal diseases. Because of the ease of use of newer camera models and their relative low cost, these cameras are employed worldwide by retina specialists to diagnose diabetic retinopathy and other degenerative diseases. Even with relative ease of use, the images produced by these systems sometimes suffer from reflectance artefacts mainly due to the nerve fibre layer (NFL) or other camera lens related reflections. We propose a technique that employs multiple fundus images acquired from the same patient to obtain a single higher quality image without these reflectance artefacts. The removal of bright artefacts, and particularly of NFL reflectance, can have great benefits for the reduction of false positives in the detection of retinal lesions such as exudate, drusens and cotton wool spots by automatic systems or manual inspection. If enough redundant information is provided by the multiple images, this technique also compensates for a suboptimal illumination. The fundus images are acquired in straightforward but unorthodox manner, i.e. the stare point of the patient is changed between each shot but the camera is kept fixed. Between each shot, the apparent shape and position of all the retinal structures that do not exhibit isotropic reflectance (e.g. bright artefacts) change. This physical effect is exploited by our algorithm in order to extract the pixels belonging to the inner layers of the retina, hence obtaining a single artefacts-free image.

Giancardo, Luca [ORNL; Meriaudeau, Fabrice [ORNL; Karnowski, Thomas Paul [ORNL; Li, Yaquin [University of Tennessee, Knoxville (UTK); Tobin Jr, Kenneth William [ORNL; Chaum, Edward [University of Tennessee, Knoxville (UTK)

2011-01-01T23:59:59.000Z

271

Over the past decade, visually based tech-niques in computer graphics have blos-  

E-Print Network (OSTI)

human eyeball. The anterior section of the eyeball contains the eye's optical system whose major fibers form the optic nerve. The spatially localized group of photoreceptors that serve a particu- lar- al system. The long axons of the retinal ganglion cells form the optic nerve, which contains about

Ferwerda, James A.

272

Functional characterization of the rod visual pigment of the echidna (Tachyglossus aculeatus), a basal mammal  

E-Print Network (OSTI)

of retinal release upon photoactivation (Farrens & Khorana, 1995; Yan et al., 2002). We perform site that has previously been referred to as meta II decay (Farrens & Khorana, 1995). Excitation and emission of arrestin, a regulator of rhodopsin photochemistry (Sommer & Farrens, 2006). In contrast, the echidna

Chang, Belinda

273

pubs.acs.org/BiochemistryPublished on Web 10/12/2010r 2010 American Chemical Society Biochemistry 2010, 49, 94259427 9425  

E-Print Network (OSTI)

-retinal chromophore. Upon light exposure, isomerization of the chromophore to its all-trans state drives Rho through-transmembrane spanning but unrelated protein, bacteriorhodopsin, indicated an essential role for internal waters in light-induced proton transfer by this protein (6). Recently, we used X-ray radiation-induced hydroxyl radical labeling

Palczewski, Krzysztof

274

Small Heat Shock Protein aA-Crystallin Prevents Photoreceptor Degeneration in Experimental  

E-Print Network (OSTI)

The small heat shock protein, aA-crystallin null (aA2/2) mice are known to be more prone to retinal degeneration than the wild type mice in Experimental Autoimmune Uveoretinitis (EAU). In this report we demonstrate that intravenous administration of aA preserves retinal architecture and prevents photoreceptor damage in EAU. Interestingly, only aA and not aB-crystallin (aB), a closely related small heat shock protein works, pointing to molecular specificity in the observed retinal protection. The possible involvement of aA in retinal protection through immune modulation is corroborated by adaptive transfer experiments, (employing aA2/2 and wild type mice with EAU as donors and Rag22/2 as the recipient mice), which indicate that aA protects against the autoimmune challenge by modulating the systemic B and T cell immunity. We show that aA administration causes marked reduction in Th1 cytokines (TNF-a, IL-12 and IFN-c), both in the retina and in the spleen; notably, IL-17 was only reduced in the retina suggesting local intervention. Importantly, expression of Toll-like receptors and their associated adaptors is also inhibited suggesting that aA protection, against photoreceptor

Autoimmune Uveitis; Narsing A. Rao; Sindhu Saraswathy; Geeta Pararajasegaram; Suraj P. Bhat

2012-01-01T23:59:59.000Z

275

Descriptions of Task Order Schedules and Placement of Pricing Information  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

RFP DE-RP36-06GO96031 RFP DE-RP36-06GO96031 10/11/2007 ATTACHMENT J-5 DESCRIPTIONS OF TASK ORDER SCHEDULES AND PLACEMENT OF PRICING INFORMATION J-5.1 DESCRIPTIONS OF TASK ORDER (TO) SCHEDULES (SCHEDULE TEMPLATES ARE PROVIDED IN ATTACHMENT J-6) J-5.1.1 Schedule TO-1 (Preliminary Assessment - PA) - Proposed Guaranteed Cost Savings and Contractor Payments - Schedule TO-1 (PA) shall be submitted to present the contractor's estimated cost savings, proposed guaranteed cost savings, and contractor payments. TO-1 (PA) values submitted may be in estimated ranges. Based on the preliminary survey and agency discussions, the contractor shall submit a completed Schedule TO-1 (PA) containing: A. Column (a) - Contractor submits proposed estimated cost savings during the implementation period, prior to full project acceptance (see most recent version

276

U.S. DEPARTMENT OF ENERGY - NETL CATEGORICAL EXCLUSION (CX) DESIGNATION FORM  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

558 558 PowerEx Inc. EE DE-EE0002558 PMC, PVT Division FY2010 Rondle Harp Jan. 1, 2010 - Dec. 31, 2011 Youngwood, PA Electric Drive Semiconductor Manufacturing Center. Advanced Battery Program. Interior modifications to existing facilities and installing additional equipment in them to expand production of semiconductor devices for electric vehicles; no new permits needed. Rondle Harp Digitally signed by Rondle Harp DN: cn=Rondle Harp, c=US, o=Power & Vehicle Technologies Division, ou=PMC PVT, email=rondle.harp@netl.doe.gov Reason: I am the author of this document Date: 2009.12.12 10:41:08 -05'00' 12 12 2009 R.P. Detwiler Digitally signed by R.P. Detwiler DN: cn=R.P. Detwiler, o=OPFC-NETL, ou, email=ralph.detwiler@netl.doe.gov, c=US Date: 2010.01.15 08:23:16 -05'00'

277

Recurrence Plot and Recurrence Quantification Analysis Techniques for Detecting a Critical Regime. Examples from Financial Market Indices  

E-Print Network (OSTI)

Recurrence Plot (RP) and Recurrence Quantification Analysis (RQA) are signal numerical analysis methodologies able to work with non linear dynamical systems and non stationarity. Moreover they well evidence changes in the states of a dynamical system. We recall their features and give practical recipes. It is shown that RP and RQA detect the critical regime in financial indices (in analogy with phase transition) before a bubble bursts, whence allowing to estimate the bubble initial time. The analysis is made on DAX and NASDAQ daily closing price between Jan. 1998 and Nov. 2003. DAX is studied in order to set-up overall considerations, and as a support for deducing technical rules. The NASDAQ bubble initial time has been estimated to be on Oct. 19, 1999.

A. Fabretti; M. Ausloos

2004-12-31T23:59:59.000Z

278

Workbook Contents  

U.S. Energy Information Administration (EIA) Indexed Site

by Pipeline " by Pipeline " ,"Click worksheet name or tab at bottom for data" ,"Worksheet Name","Description","# Of Series","Frequency","Latest Data for" ,"Data 1","Total Crude by Pipeline ",6,"Annual",2012,"6/30/1981" ,"Release Date:","6/22/2012" ,"Next Release Date:","6/21/2013" ,"Excel File Name:","pet_pnp_caprec_a_(na)_8rp0_mbbl_a.xls" ,"Available from Web Page:","http://www.eia.gov/dnav/pet/pet_pnp_caprec_a_(na)_8rp0_mbbl_a.htm" ,"Source:","Energy Information Administration" ,"For Help, Contact:","infoctr@eia.gov" ,,"(202) 586-8800",,,"7/30/2013 10:52:52 AM"

279

Descriptions of Task Order Schedules and Placement of Pricing Information  

NLE Websites -- All DOE Office Websites (Extended Search)

RFP DE-RP36-06GO96031 RFP DE-RP36-06GO96031 10/11/2007 ATTACHMENT J-5 DESCRIPTIONS OF TASK ORDER SCHEDULES AND PLACEMENT OF PRICING INFORMATION J-5.1 DESCRIPTIONS OF TASK ORDER (TO) SCHEDULES (SCHEDULE TEMPLATES ARE PROVIDED IN ATTACHMENT J-6) J-5.1.1 Schedule TO-1 (Preliminary Assessment - PA) - Proposed Guaranteed Cost Savings and Contractor Payments - Schedule TO-1 (PA) shall be submitted to present the contractor's estimated cost savings, proposed guaranteed cost savings, and contractor payments. TO-1 (PA) values submitted may be in estimated ranges. Based on the preliminary survey and agency discussions, the contractor shall submit a completed Schedule TO-1 (PA) containing: A. Column (a) - Contractor submits proposed estimated cost savings during the implementation period, prior to full project acceptance (see most recent version

280

Microsoft Word - Attachment L-4, Corporate Experience Matrix _Amendment 3_ Ex for website.doc  

NLE Websites -- All DOE Office Websites (Extended Search)

DE-RP52-08NA28091 DE-RP52-08NA28091 Attachment L-4 April 29, 2008 [Submit in Volume II, TAB 3] EXAMPLE CORPORATE EXPERIENCE MATRIX Offeror/Team Member: XYZ Company Proposed Role in Accomplishing ECRS PWS: Lead for Soils Sub-Project and Project Controls Performance Work Statement (PWS) Areas (2) Identify Client/ Contract # Below (1): Soils Sub- Project (3.1.2.1) UGTA Sub- Project (3.1.2.2.) Industrial Sites Sub- Project (3.1.2.3) Project Controls (3.2.1) Other Program Support (3.2.2 - 3.2.6) Public Involvement Activities (3.2.7) NNSA/ DE-AC52- 07NAxxxxx P P Can-Do Company/xx xxxxxxx S2 S2 EPA/ xxxxxxx P Instructions: (1) Insert the name of the client and contract number from the Corporate Experience & Self-Assessment Form (Attachment L-3).

Note: This page contains sample records for the topic "retinitis pigmentosa rp" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


281

Proc. Pac. Symp. Biocomp. (PSB), 2004. GEOMETRIC ANALYSIS OF CROSS-LINKABILITY  

E-Print Network (OSTI)

DISCRIMINATION S. POTLURI1 , A.A. KHAN1 , A. KUZMINYKH2 , J.M. BUJNICKI3 , A.M. FRIEDMAN4 , C. BAILEY-KELLOGG1. 1 #12;2. Cross-link p q r 3. Proteolytically digest1. Model / predict (a) (b) 4. Interpret mass spectrum q rp => model (a) m/z Figure 1: Cross-linking mass spectrometry protocol. (1) Computationally

Bailey-Kellogg, Chris

282

Khesbn No. 127 - Spring 1996 - Journal  

E-Print Network (OSTI)

7rx 1ub; oy'] I'lt - D'rp')rti[D r't I'tl ''ll5! ll6n ll'' .l? u! yD lup'ititut'lN ot.r . 'rtI t]DS l,tD rSE B ltgl tr ,Errnp ry lrbyr u'D 1tnfr ''rti pr u? '! ul:tit lryri; .r!

Admin, LAYCC

1996-01-01T23:59:59.000Z

283

Effects of phase transformation of steam-water relative permeabilities  

DOE Green Energy (OSTI)

A combined theoretical and experimental study of steam-water relative permeabilities (RPs) was carried out. First, an experimental study of two-phase concurrent flow of steam and water was conducted and a set of RP curves was obtained. These curves were compared with semi-empirical and experimental results obtained by other investigators for two-phase, two-component flow (oil/gas; gas/water; gas/oil). It was found that while the wetting phase RPs were in good agreement, RPs for the steam phase were considerably higher than the non-wetting phase RPs in two-component systems. This enhancement of steam RP is attributed to phase transformation effects at the pore level in flow channels. The effects of phase transformation were studied theoretically. This study indicates that there are two separate mechanisms by which phase transformation affects RP curves: (1) Phase transformation is converging-diverging flow channels can cause an enhancement of steam phase RP. In a channel dominated by steam a fraction of the flowing steam condenses upstream from the constriction, depositing its latent heat of condensation. This heat is conducted through the solid grains around the pore throat, and evaporation takes place downstream from it. Therefore, for a given bulk flow quality; a smaller fraction of steam actually flows through the throat segments. This pore-level effect manifests itself as relative permeability enhancement on a macroscopic level; and (2) phase transformation along the interface of a stagnant phase and the phase flowing around it controls the irreducible phase saturation. Therefore, the irreducible phase saturation in steam-water flow will depend, among other factors, on the boundary conditions of the flow.

Verma, A.K.

1986-03-01T23:59:59.000Z

284

Low doses of neutrons induce changes in gene expression  

SciTech Connect

Studies were designed to identify genes induced in fibroblasts after exposure to low-dose neutron radiation but not after {gamma} rays. Our past work had shown similar modulation of transcripts for {alpha}-tubulin, {beta}- and {gamma}-actins, ornithine decarboxylase and interleukin 1 after exposure to either neutrons or {gamma} rays. However, differences in the expression of {beta}-protein kinase C and c-fos genes were observed, with both being induced after exposure to {gamma} rays but not neutrons. Recently, we have identified two genes that are induced after exposure to neutrons but not {gamma} rays: Rp-8 (a gene associated with apoptosis) and the long terminal repeat (LTR) of the human immunodeficiency virus (HIV). Induction of Rp-8 mRNA was demonstrated in Syrian hamster embryo (SHE) fibroblasts and was found to be induced in cells exposed to neutrons administered at low (0.005 Gy/min) and high dose rate (0.12 Gy/min). No induction of other genes associated with apoptosis such as Rp-2, bcl-2 and Tcl-30 was observed. The induction of transcription from the LTR of HIV was demonstrated in HeLa cells bearing a transfected construct of the chloramphenicol acetyl transferase (CAT) gene driven by the HIV-LTR promoter. Measurements of CAT activity and CAT transcripts after irradiation demonstrated an unresponsiveness to {gamma} rays over a broad range of doses (0.1-3 Gy). Twofold induction of the HIV-LTR was detected after exposure to neutrons (0.48 Gy) administered at low (0.05 Gy/min) but not high (0.12 Gy/min) dose rates. Ultraviolet-mediated HIV-LTR induction, however, was inhibited by exposure to low-dose-rate neutron irradiation. These results are interesting in light of reports that Rp-8 is induced during apoptosis and that HIV causes apoptosis. 17 refs., 3 figs., 1 tab.

Woloschak, G.E.; Chang-Liu, C.M. [Argonne National Lab., IL (United States); Panozzo, J.; Libertin, C.R. [Loyola Univ. of Chicago, Maywood, IL (United States)

1994-04-01T23:59:59.000Z

285

The effects of practice distribution upon the regional oscillatory activity in visuomotor learning  

E-Print Network (OSTI)

the difference between a changing foreground stimulus and a constant background stimu- lus. Participants were seated in front of a 17 monitor (resolution of 800 600 pixels), at a distance of approximately 1 m. The foreground stimulus consisted of a green... of the distributed training group were presented with a commer- cial radio play via standard headphones (Technics Stereo Headphones RP-F550). Participants were instructed to pay attention to the radio play and press a button each time a particular character...

Studer, Bettina; Koeneke, Susan; Blum, Julia; Jancke, Lutz

2010-01-22T23:59:59.000Z

286

Clinical and Dosimetric Predictors of Radiation Pneumonitis in a Large Series of Patients Treated With Stereotactic Body Radiation Therapy to the Lung  

SciTech Connect

Purpose: To report clinical and dosimetric factors predictive of radiation pneumonitis (RP) in patients receiving lung stereotactic body radiation therapy (SBRT) from a series of 240 patients. Methods and Materials: Of the 297 isocenters treating 263 patients, 240 patients (n=263 isocenters) had evaluable information regarding RP. Age, gender, current smoking status and pack-years, O{sub 2} use, Charlson Comorbidity Index, prior lung radiation therapy (yes/no), dose/fractionation, V{sub 5}, V{sub 13}, V{sub 20}, V{sub prescription}, mean lung dose, planning target volume (PTV), total lung volume, and PTV/lung volume ratio were recorded. Results: Twenty-nine patients (11.0%) developed symptomatic pneumonitis (26 grade 2, 3 grade 3). The mean V{sub 20} was 6.5% (range, 0.4%-20.2%), and the average mean lung dose was 5.03 Gy (0.547-12.2 Gy). In univariable analysis female gender (P=.0257) and Charlson Comorbidity index (P=.0366) were significantly predictive of RP. Among dosimetric parameters, V{sub 5} (P=.0186), V{sub 13} (P=.0438), and V{sub prescription} (where dose = 60 Gy) (P=.0128) were significant. There was only a trend toward significance for V{sub 20} (P=.0610). Planning target volume/normal lung volume ratio was highly significant (P=.0024). In multivariable analysis the clinical factors of female gender, pack-years smoking, and larger gross internal tumor volume and PTV were predictive (P=.0094, .0312, .0364, and .052, respectively), but no dosimetric factors were significant. Conclusions: Rate of symptomatic RP was 11%. Our mean lung dose was <600 cGy in most cases and V20 <10%. In univariable analysis, dosimetric factors were predictive, while tumor size (or tumor/lung volume ratio) played a role in multivariable and univariable and analysis, respectively.

Baker, Ryan [University of South Florida School of Medicine, Tampa, Florida (United States)] [University of South Florida School of Medicine, Tampa, Florida (United States); Han Gang [Department of Biostatistics, Moffitt Cancer Center, Tampa, Florida (United States)] [Department of Biostatistics, Moffitt Cancer Center, Tampa, Florida (United States); Sarangkasiri, Siriporn; DeMarco, MaryLou; Turke, Carolyn; Stevens, Craig W. [Department of Radiation Oncology, Moffitt Cancer Center, Tampa, Florida (United States)] [Department of Radiation Oncology, Moffitt Cancer Center, Tampa, Florida (United States); Dilling, Thomas J., E-mail: Thomas.Dilling@Moffitt.org [Department of Radiation Oncology, Moffitt Cancer Center, Tampa, Florida (United States)

2013-01-01T23:59:59.000Z

287

Khesbn no. 69-70 - Fall 1972 - Journal  

E-Print Network (OSTI)

$ t$Ftl) Etl Fg E?! rp : ttl$ftt$Ftut lrl:tlltt! ,$1] . ]!i$ -5t1N rj IlN ttllrul ttl ;J! i2llD yptr:pr t7rr11 1lS -ytD! ] N llIl3o'D lr:Si7 ttl 0$11 ,D'ltpl;'l JtrI n),

Admin, LAYCC

1972-01-01T23:59:59.000Z

288

Dpartement Mention Spcialits Etablissements  

E-Print Network (OSTI)

cellulaire (R) Sciences des matériaux et nanoobjets (R) Systèmes dynamiques et statistiques de la matière-radioprotection (R/P) Observatoire de Paris, Paris 11, Ecole Centrale Physique fondamentale et Sciences pour l Protéines (R) Biophysique moléculaire et cellulaire (R) Paris 7 Sciences du Végétal Sciences du Végétal (R

Gutkin, Boris

289

A Briv un An Entfer (A Letter and a Reply)  

E-Print Network (OSTI)

TTypwip-Tagnya** x _ r x rp^anp px p s ^ n x a*a i n ^n'a a$isnr a&n px 3 D # T O * I s p*anp n P X " nxirr o m i a^ap^as;' "a T 8 * nsa^n px ? p*anp yas^aTO sfry-Tnt * Y I w x

1979-01-01T23:59:59.000Z

290

Application of the EPRI Standard Radiation Monitoring Program for PWR Radiation Field Reduction  

Science Conference Proceedings (OSTI)

The NEI/INPO/EPRI RP 2020 Initiative was developed to promote radiation dose reduction by emphasizing radiological protection fundamentals and reducing radioactive source term. EPRI was charged as the technical lead in the area of source term reduction. EPRI's Radiation Management program initiated a multi-year program to develop an understanding of source term generation and transport with the eventual goal of providing plant specific recommendations for source term reduction. Reinstatement of the Stand...

2007-11-28T23:59:59.000Z

291

Radiation Field Control Manual  

Science Conference Proceedings (OSTI)

The EPRI Radiation Management Program is dedicated to reducing nuclear power plant worker personnel exposure by developing practices and technologies to increase the radiation protection of the worker, and to implement methods to reduce radiation fields. The nuclear power industry has recently implemented the RP2020 Initiative to promote positive radiation protection trends. Control of radiation fields is crucial to one of the initiative goals of reducing exposure. This manual provides the current state ...

2004-12-16T23:59:59.000Z

292

Horn OperationalHorn Operational in K2K, MiniBoone,  

E-Print Network (OSTI)

exchange 12G V / 6E12· 12GeV / 6E12 ppp "accessible" (RP) No time/money spent on remote handling design·Design with remote handling in mind ·Foresee full set of spares 04/07/2008 Ans PARDONS, NuFact2008 7 #12;Mini cyclesDesign: 1E7 cycles Remote handling, work cell builtwork cell built 04/07/2008 Ans PARDONS, Nu

McDonald, Kirk

293

Bike/ped bridge To MountainView  

E-Print Network (OSTI)

Stadium Rains Vaden Escondido Village SLAC National Accelerator Laboratory Rosewood Hotel Flo Mo Town A M I N O R E A L UNIVERSITY AVE ALMA ST Palo Alto Transit Center (PATC) RP S YX N O SE P MC Target Holiday Service Hours: Monday - Friday, 7:30 a.m. - 5:00 p.m. Phone: 650.723.9362 650 . 724.4309 (Dispatch

Prinz, Friedrich B.

294

EPRI Integrated Dose Reduction Program Pilot Study  

Science Conference Proceedings (OSTI)

The Integrated Dose Reduction (IDR) project is an integral part of EPRI's support to nuclear plant radiation protection programs. The broad objective of the IDR program is to review existing and recent industry developments and provide utilities with an integrated plan for EPRI's assistance based on a plant's specific needs. This document describes a pilot test of this product at a host site, and identifies areas where EPRI's RP assessments and technical assistance can support key plant programs.

2003-11-21T23:59:59.000Z

295

Radiation Protection Program Resource Optimization Project; Brunswick Nuclear Plant  

Science Conference Proceedings (OSTI)

Radiation protection (RP) managers face challenges in providing a necessary service that complies with stringent regulations, while simultaneously reducing operations and maintenance (O&M) costs. The results of this pilot project, hosted by Brunswick Nuclear Plant (BNP), will assist utilities in targeting resource commitments and cost effectiveness while optimizing overall performance. This report identifies specific program cost reduction and process performance enhancements for the host plant, and esta...

2002-11-18T23:59:59.000Z

296

EnergyPlusDeST DOE-2.1E Building energy modeling programs comparison  

E-Print Network (OSTI)

ST #12; 1 IEA BESTest ASHRAE Standard 140[1] [2] 1 EnergyPlus, DeST, DOE-2, ESP, BLAST TRNSYS 1 ASHRAE RP865[1] 2ANSI/ASHRAE Standard 140 [4] 3 IEA SHC BESTest / [5] EnergyPlus [6] [7 4 EnergyPlus DeST 4 #12; 4 4.1 CAVVAV ASHRAE Standard 90.1-2004 EnergyPlus De

297

Response to Congressional inquiry regarding seepage basins at the Savannah River Site  

SciTech Connect

This report has been prepared in response to the request by the House Appropriations Committee to address the permanent isolation and containment/removal of the contaminants associated with the seepage basins at the Savannah River Site (SRS). Many of the activities regarding groundwater monitoring and status referred to in this report will be discussed in detail in a companion report on the Groundwater Monitoring Program at the SRS [(U), WSRC-RP-89-889].

1989-11-22T23:59:59.000Z

298

Evaluating candidate lost circulation materials for geothermal drilling  

DOE Green Energy (OSTI)

Sandia National Laboratories' Geothermal Technology Development Division is working to advance the state of the art of lost circulation prevention and control. For this purpose, a large-scale lost Circulation Test Facility was designed and built. This paper addresses the evaluation of candidate lost circulation materisl using this facility and also using the recommended practice of API RP 131. Test results from these facilities are compared and discussed for the materials tested.

Loeppke, G.

1986-01-01T23:59:59.000Z

299

Don't mess with H/sub 2/S  

Science Conference Proceedings (OSTI)

The American Petroleum Institute issued a report on ''Recommended Practices for Safe Drilling of Wells Containing Hydrogen Sulfide.'' The study (RP49) updates a first edition published in September 1974. It provides a solid overview of preventive steps that should be taken to safeguard crew and equipment when drilling through H/sub 2/S zones. Discussions cover personnel training, protective equipment, wellsite layout, rig and well equipment, general rig operations and contingency planning and emergency procedures. This article summarizes the report.

Not Available

1987-09-01T23:59:59.000Z

300

PWR Standard Radiation Monitoring Program: 2013 Summary  

Science Conference Proceedings (OSTI)

The Nuclear Energy Institute/Institute of Nuclear Power Operations/Electric Power Research Institute (EPRI) Radiation Protection RP 2020 Initiative was developed to promote radiation dose reduction by emphasizing radiological protection fundamentals and reducing radioactive source term. EPRI was charged as the technical lead in the area of source term reduction, and EPRIs Radiation Management Program initiated a multi-year program to develop an understanding of source term ...

2013-06-27T23:59:59.000Z

Note: This page contains sample records for the topic "retinitis pigmentosa rp" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


301

Physician Beliefs and Practices for Adjuvant and Salvage Radiation Therapy After Prostatectomy  

SciTech Connect

Purpose: Despite results of randomized trials that support adjuvant radiation therapy (RT) after radical prostatectomy (RP) for prostate cancer with adverse pathologic features (APF), many clinicians favor selective use of salvage RT. This survey was conducted to evaluate the beliefs and practices of radiation oncologists (RO) and urologists (U) regarding RT after RP. Methods and Materials: We designed a Web-based survey of post-RP RT beliefs and policies. Survey invitations were e-mailed to a list of 926 RO and 591 U. APF were defined as extracapsular extension, seminal vesicle invasion, or positive surgical margin. Differences between U and RO in adjuvant RT recommendations were evaluated by comparative statistics. Multivariate analyses were performed to evaluate factors predictive of adjuvant RT recommendation. Results: Analyzable surveys were completed by 218 RO and 92 U (overallresponse rate, 20%). Adjuvant RT was recommended based on APF by 68% of respondents (78% RO, 44% U, p <0.001). U were less likely than RO to agree that adjuvant RT improves survival and/or biochemical control (p < 0.0001). PSA thresholds for salvage RT were higher among U than RO (p < 0.001). Predicted rates of erectile dysfunction due to RT were higher among U than RO (p <0.001). On multivariate analysis, respondent specialty was the only predictor of adjuvant RT recommendations. Conclusions: U are less likely than RO to recommend adjuvant RT. Future research efforts should focus on defining the toxicities of post-RP RT and on identifying the subgroups of patients who will benefit from adjuvant vs. selective salvage RT.

Showalter, Timothy N., E-mail: timothy.showalter@jeffersonhospital.org [Department of Radiation Oncology, Jefferson Medical College, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA (United States); Ohri, Nitin; Teti, Kristopher G. [Department of Radiation Oncology, Jefferson Medical College, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA (United States); Foley, Kathleen A. [Strategic Consulting, Thomson Reuters Healthcare, Cambridge, MA (United States); Keith, Scott W. [Division of Biostatistics, Department of Pharmacology and Experimental Therapeutics, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA (United States); Trabulsi, Edouard J.; Lallas, Costas D. [Department of Urology, Jefferson Medical College and Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA (United States); Dicker, Adam P. [Department of Radiation Oncology, Jefferson Medical College, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA (United States); Hoffman-Censits, Jean [Department of Medical Oncology, Jefferson Medical College and Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA (United States); Pizzi, Laura T. [School of Pharmacy, Thomas Jefferson University, Philadelphia, PA (United States); Gomella, Leonard G. [Department of Urology, Jefferson Medical College and Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA (United States)

2012-02-01T23:59:59.000Z

302

Acoustic Emission for High-Energy Piping: A State-of-Knowledge Summary  

Science Conference Proceedings (OSTI)

This report pulls together information on the application of acoustic emission (AE) testing for monitoring high-energy piping in fossil power plants. The experience data reviewed include the Electric Power Research Institute (EPRI) initiatives under research project RP1893 (circa 19861995) that culminated in the 1995 monitoring guidelines for hot reheat piping and available post-guidelines field applications through to the present. EPRI has had more than two decades of application experience ...

2013-11-14T23:59:59.000Z

303

Proceedings: 2003 Radiation Protection Technology Conference  

SciTech Connect

Health physics professionals within the nuclear industry are continually upgrading their programs with new methods and technologies. The Third Annual EPRI Radiation Protection Technology Conference facilitated this effort by communicating technical developments, program improvements, and experience throughout the nuclear power industry. When viewed from the perspective of shorter outages, diminishing numbers of contract RP technicians and demanding emergent work, this information flow is critical for the industry.

None

2004-04-01T23:59:59.000Z

304

Khesbn No. 127 - Spring 1996 - Journal  

E-Print Network (OSTI)

R rtt )] o'np D'rt"! ,'yp"'rtD; 1R'Dpti"t D'l I'N ? tltDgrx igl lrr ? l]rp ? 1N rgi-rtD l,tp fpt' pt",l,t p* ur6b7 . ?ltlyr t'N 'po:f'? t;3i )RtD" .olgDtj? t1'N tt 1tx rtu6ryu')

Admin, LAYCC

1996-01-01T23:59:59.000Z

305

Proceedings: 2003 Radiation Protection Technology Conference  

Science Conference Proceedings (OSTI)

Health physics professionals within the nuclear industry are continually upgrading their programs with new methods and technologies. The Third Annual EPRI Radiation Protection Technology Conference facilitated this effort by communicating technical developments, program improvements, and experience throughout the nuclear power industry. When viewed from the perspective of shorter outages, diminishing numbers of contract RP technicians and demanding emergent work, this information flow is critical for the...

2004-04-13T23:59:59.000Z

306

Annual progress report, December 1, 1979-November 30, 1980  

Science Conference Proceedings (OSTI)

Structure and function in photosynthetic membranes and their components continue to be studied, principally with Rhodopseudomonas sphaeroides. We have discovered how to remove bacteriochlorophyll (bchl) from a specific binding site in the antenna pigment-protein complex B850, and to replace the bchl without denaturing the complex. This has never before been achieved for any photosynthetic chlorophyllprotein complex. It opens a substantial vista of experiments designed to elucidate the nature of the binding site. Our analyses of the B850 and B875 complexes cast doubt on the accepted ratios of bchl components, carotenoids and protein and hence on models based on these ratios. We have shown that Rp. sphaeroides contains a specific second quinone (Q/sub b/) in contact with the primary photochemical electron acceptor (Q/sub a/) and distinct from the molecules of a larger pool of quinone. We have resolved conflicting reports about the polypeptide composition of reaction centers from Rhodopseudomonas viridis. We have new data on the orientation, relative to the photosynthetic membrane, of cytochrome 552 in Rp. viridis and of the shifting component of carotenoid in Rp. sphaeroides. We have constructed and are using a new circular dichroism spectrometer.

Clayton, R.K.

1980-01-01T23:59:59.000Z

307

Recovery of Navy distillate fuel from reclaimed product. Volume II. Literature review  

SciTech Connect

In an effort to assist the Navy to better utilize its waste hydrocarbons, NIPER, with support from the US Department of Energy, is conducting research designed to ultimately develop a practical technique for converting Reclaimed Product (RP) into specification Naval Distillate Fuel (F-76). This first phase of the project was focused on reviewing the literature and available information from equipment manufacturers. The literature survey has been carefully culled for methodology applicable to the conversion of RP into diesel fuel suitable for Navy use. Based upon the results of this study, a second phase has been developed and outlined in which experiments will be performed to determine the most practical recycling technologies. It is realized that the final selection of one particular technology may be site-specific due to vast differences in RP volume and available facilities. A final phase, if funded, would involve full-scale testing of one of the recommended techniques at a refueling depot. The Phase I investigations are published in two volumes. Volume 1, Technical Discussion, includes the narrative and Appendices I and II. Appendix III, a detailed Literature Review, includes both a narrative portion and an annotated bibliography containing about 800 references and abstracts. This appendix, because of its volume, has been published separately as Volume 2.

Brinkman, D.W.; Whisman, M.L.

1984-11-01T23:59:59.000Z

308

Voltage stability/security assessment and on-line control  

SciTech Connect

Project RP3040-1 was initiated in 1989, and concluded with the release of the Voltage Stability analysis program, VSTAB, in 1992. VSTAB is a production grade program for voltage stability assessment of large complex power systems. During the course of the RP3040-1, much effort was spent in developing a clear understanding of voltage stability and in defining the special modeling and analytical techniques required to accurately capture the phenomenon through simulation. The result was the development of new steady state methods which can complement the dynamic simulation methods currently available with EPRI's Extended Transient/Midterm Stability Program (ETMSP). VSTAB uses an enhanced powerflow combined with a specially developed modal analysis algorithm to provide information regarding both the proximity to, and mechanism of, voltage instability. The program is fast, easy to use, and comprehensive in both modeling and analysis features. This Programmer's Manual documents the structure and code details of VSTAB. It is intended as a reference document for those required to maintain or enhance the VSTAB program. For details on analytical techniques used in the program, readers are directed to the VSTAB Application Guide and Final Report for project RP3040-1.

Morison, G.K.; Gao, B.; Hamadanizadeh, H. (Ontario Hydro, Toronto, ON (Canada))

1993-04-01T23:59:59.000Z

309

Science& Technology Review November 2003  

DOE Green Energy (OSTI)

This issue of Science & Technology Review covers the following topics: (1) We Will Always Need Basic Science--Commentary by Tomas Diaz de la Rubia; (2) When Semiconductors Go Nano--experiments and computer simulations reveal some surprising behavior of semiconductors at the nanoscale; (3) Retinal Prosthesis Provides Hope for Restoring Sight--A microelectrode array is being developed for a retinal prosthesis; (4) Maglev on the Development Track for Urban Transportation--Inductrack, a Livermore concept to levitate train cars using permanent magnets, will be demonstrated on a 120-meter-long test track; and (5) Power Plant on a Chip Moves Closer to Reality--Laboratory-designed fuel processor gives power boost to dime-size fuel cell.

McMahon, D

2003-11-01T23:59:59.000Z

310

Functional expression of the heteromeric olfactory cyclic nucleotide-gated channel in the hippocampus: a potential effector of synaptic plasticity in brain neurons  

E-Print Network (OSTI)

Cyclic nucleotide-gated (cng) channels are important components of signaling systems mediating sensory transduction. In vertebrate photoreceptors, light activates a signaling cascade that causes a decrease in intracellular cGMP concentrations, closing retinal cng channels. Signal transduction in olfactory receptor neurons is believed to proceed via G-proteinmediated elevation of intracellular cAMP in response to odorant binding by 7-helix receptors. cAMP opens the olfactory cng channel, which is highly permeable to Ca 2 ?. Here we demonstrate by in situ hybridization and immunohistochemistry with subunit-specific antibodies that both subunits of the heteromeric rat olfactory cng channel are also widely expressed in the brain. Expression of the retinal rod cng channel, however, can be detected only in the eye. In the adult hippocampus, the olfactory cng channel is expressed on cell bodies and processes

Jonathan Bradley; A Yinong Zhang; A Robert Bakin; Henry A. Lester; Gabriele V. Ronnett; Kai Zinn

1997-01-01T23:59:59.000Z

311

CRADA Members Published Papers  

NLE Websites -- All DOE Office Websites (Extended Search)

Published Papers Related to the DOE Artificial Retina Project CRADA Published Papers Related to the DOE Artificial Retina Project CRADA 2009 Basinger, B. C., A. P. Rowley, K. Chen, M. S. Humayun, J. D. Weiland. 2009. "Finite Element Modeling of Retinal Prosthesis Mechanics," Journal of Neural Engineering 6(5), 55006. Behrend, M. R., A. K. Ahuja, M. S. Humayun, J. D. Weiland, and R. H. Chow. 2009. "Selective Labeling of Retinal Ganglion Cells with Calcium Indicators by Retrograde Loading In Vitro," Journal of Neuroscience Methods 179(2), 166-72. Caspi, A., J. D. Dorn, K. H. McClure, M. S. Humayun, R. J. Greenberg, and M. J. McMahon. 2009. "Feasibility Study of a Retinal Prosthesis: Spatial Vision with a 16-Electrode Implant," Archives of Ophthalmology 127(4), 398-401. Greenbaum, E., M. S. Humayun, C. A. Sanders, D. Close, H. M. O'Neill, and B. R. Evans. 2009. "Metabolic Prosthesis for Oxygenation of Ischemic Tissue," IEEE Transactions on Biomedical Engineering 56(2), 528-31.

312

Are mirror planets opaque?  

E-Print Network (OSTI)

Over the last few years, many close orbiting ($\\sim 0.05$ A.U.) large mass planets ($\\sim M_{J}$) of nearby stars have been discovered. Their existence has been inferred from tiny Doppler shifts in the light from the star and in one case a transit has been observed. Because ordinary planets are not expected to be able to form this close to ordinary stars due to the high temperatures, it has been speculated that the close-in large planets are in fact exotic heavenly bodies made of mirror matter. We show that the accretion of ordinary matter onto the mirror planet (from e.g.the solar wind from the host star) should make the mirror planet opaque to ordinary radiation with an effective radius ($R_p$) large enough to explain the measured size of the transiting close-in extrasolar planet, HD209458b. Furthermore we obtain the rough prediction that $R_{p} \\propto \\sqrt{{T_s\\over M_p}}$ (where $T_s$, is the surface temperature of the ordinary matter in the mirror planet and $M_p$ is the mass of the mirror planet) which will be tested in the near future as more transiting planets are found. We also show that the mirror world interpretation of the close-in extra solar planets explains the low albedo of $\\tau$ Boo b because the large estimated mass of $\\tau$ Boo b ($\\sim 7M_J$) implies a small effective radius of $R_p \\approx 0.5R_J$ for $\\tau$ Boo.

R. Foot

2001-01-04T23:59:59.000Z

313

Infinity Cancellation, Type I ? Compactification and String S-Matrix Functional 1  

E-Print Network (OSTI)

Nonvanishing tadpoles and possible infinities associated in the multiparticle amplitudes are discussed with regard to the disk and RP 2 diagrams of the Type I ? compactification. We find that the infinity cancellation of SO(32) type I theory extends to this case as well despite the presence of tadpoles localized in the D-brane worldvolume and the orientifold surfaces. Formalism of string S-matrix generating functional is presented to find a consistent string background as c-number source function: we find this only treats the cancellation of the tadpoles in the linearized approximation. Our formalism automatically provides representation of the string amplitudes on this background to all orders in ? ?. 1

Y. Arakane; H. Itoyama; H. Kunitomo; A. Tokura

1996-01-01T23:59:59.000Z

314

Portsmouth DUF6 Conversion Final EIS - Appendix D: Environmental Synopsis for the Depleted UF6 Conversion Project  

NLE Websites -- All DOE Office Websites (Extended Search)

Portsmouth DUF Portsmouth DUF 6 Conversion Final EIS APPENDIX D: ENVIRONMENTAL SYNOPSIS FOR THE DEPLETED UF 6 CONVERSION PROJECT Environmental Synopsis D-2 Portsmouth DUF 6 Conversion Final EIS ENVIRONMENTAL SYNOPSIS FOR THE DEPLETED UF 6 CONVERSION PROJECT (Solicitation No. DE-RP05-01OR22717) October 2002 Environmental Assessment Division Argonne National Laboratory Argonne, Illinois Prepared for Office of Site Closure - Oak Ridge Office (EM-32) Office of Environmental Management U.S. Department of Energy Washington, D.C. October 2002 iii CONTENTS 1 INTRODUCTION........................................................................................................... 1 2 BACKGROUND.............................................................................................................

315

Microsoft Word - PADSBriefingContents.Doc  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

CONTENTS CONTENTS Page(s) Highlights of PADSWeb Changes 1 Central Contractor Registration Process 3 - 4 DUNS Number and CCR Process 5 - 8 Contracting Officer's Determination of Business Size Process 9 Procurement - Data Field Changes New FY 2004 Data Fields 11 - 12 Data Fields Removed 13 Data Fields Revised 14 New and Revised Codes 15 - 21 IPAR Data Entry Forms Financial Assistance - Add/Change Basic 22 Financial Assistance - Add Mod 23 Procurement - Add Basic Stand Alone Contracts (TPAIs of AC, RL, RO, RP) 24 Procurement - Add Basic Purchase Orders, and Simplified Acquisition Small Demo (TPAIs of AF and AX) 25 Procurement - Add Basic Delivery and Task

316

Paducah DUF6 Conversion Final EIS - Appendix D: Environmental Synopsis for the Depleted UF6 Conversion Project  

NLE Websites -- All DOE Office Websites (Extended Search)

Paducah DUF Paducah DUF 6 Conversion Final EIS APPENDIX D: ENVIRONMENTAL SYNOPSIS FOR THE DEPLETED UF 6 CONVERSION PROJECT Environmental Synopsis D-2 Paducah DUF 6 Conversion Final EIS ENVIRONMENTAL SYNOPSIS FOR THE DEPLETED UF 6 CONVERSION PROJECT (Solicitation No. DE-RP05-01OR22717) October 2002 Environmental Assessment Division Argonne National Laboratory Argonne, Illinois Prepared for Office of Site Closure - Oak Ridge Office (EM-32) Office of Environmental Management U.S. Department of Energy Washington, D.C. October 2002 iii CONTENTS 1 INTRODUCTION........................................................................................................... 1 2 BACKGROUND............................................................................................................. 3 3

317

Determining Long-Term Performance of Cool Storage Systems from Short-Term Tests, Final Report  

E-Print Network (OSTI)

This is the final report for ASHRAE Research Project 1004-RP: Determining Long-Term Performance of Cool Storage Systems from Short-Term Tests. This report presents the results of the development and application of the methodology to Case Study #2, the Delmar College, in Corpus Christi, Texas, and Case Study #3, the Austin Convention Center, in Austin, Texas. A previous report presented the analysis results for Case Study #1, which was a large hotel located in San Francisco, CA. This report also includes a summary and discussion of the results from all three case studies, recommendations for further research, and a step-by-step guide to applying the analysis methodology.

Reddy, T. A.; Elleson, J.; Haberl, J. S.

2000-01-01T23:59:59.000Z

318

The dc modeling program (DCMP): Version 2. 0  

Science Conference Proceedings (OSTI)

In this project one of the main objectives was the refinement of tools for the study of HVDC systems. The original software was prepared in project RP1964-2 (EL-4365) as power flow and stability program models for HVDC systems. In this project new modeling capabilities were added to both the power flow and stability models. Additionally, the HVDC specific model capabilities were integrated into a new program, termed the Standalone program, for use in the development and testing of HVDC models. This manual provides technical background for programmers and those interested in understanding, augmenting or transporting the dc models.

Chapman, D.G. (Manitoba HVDC Research Centre, Winnipeg, MB (Canada))

1990-08-01T23:59:59.000Z

319

The dc modeling program (DCMP): Version 2. 0  

Science Conference Proceedings (OSTI)

In this project one of the main objectives was the refinement of tools for the study of HVDC systems. The original software was prepared in project RP1964-2 (EL-4365) as power flow and stability program models for HVDC systems. In this project new modeling capabilities were added to both the power flow and stability models. Additionally, the HVDC specific model capabilities were integrated into a new program, termed the Standalone program, for use in the development and testing of HVDC models.

Chapman, D.G. (Manitoba HVDC Research Centre, Winnipeg, MB (Canada))

1990-08-01T23:59:59.000Z

320

The dc modeling program (DCMP): Version 2. 0  

SciTech Connect

In this project one of the main objectives was the refinement of tools for the study of HVDC systems. The original software was prepared in project RP1964-2 (EL-4365) as power flow and stability program models for HVDC systems. In this project new modeling capabilities were added to both the power flow and stability models. Additionally, the HVDC specific model capabilities were integrated into a new program, termed the Standalone program, for use in the development and testing of HVDC models. This volume provides information on the application of the software in the form of a User's Manual.

Chapman, D.G. (Manitoba HVDC Research Centre, Winnipeg, MB (Canada))

1990-08-01T23:59:59.000Z

Note: This page contains sample records for the topic "retinitis pigmentosa rp" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


321

Baseline Report for the Fort Hood Army Base: Sept. 1, 2002 - Aug. 31, 2003  

E-Print Network (OSTI)

This report presents electricity, natural gas and cooling baselines for the thermal plant, buildings located in the 87000 block, III Corp building and other buildings that were determined to be part of the ESPC project at Ft. Hood. A baseline analysis is also presented for the natural gas consumption for the Ft. Hood Army base. The weather-independent analysis, which utilizes 24-hour profiles that were developed using ASHRAE??s 1093-RP diversity factor procedures are presented for data obtained from portable loggers attached to Watt-hour meters in selected buildings as well as data from the Main, West and North Substations.

Haberl, J. S.; Baltazar-Cervantes, J. C.; Liu, Z.; Claridge, D. E.; Turner, W. D.

2003-01-01T23:59:59.000Z

322

Spatial Averaging of Fields from Half-wave Dipole Antennas and Corresponding SAR Calculations in the NORMAN Human Voxel Model Betwee n 65 MHz and 2 GHz  

Science Conference Proceedings (OSTI)

Status: Published Citation: Findlay, RP; and Dimbylow, PJ. 2009. Spatial Averaging of Fields from Half-wave Dipole Antennas and Corresponding SAR Calculations in the NORMAN Human Voxel Model Between 65 MHz and 2 GHz. In Physics in Medicine and Biology, Volume 54, Number 8, 2009, pp. 2437-2447. This RF exposure research is the second part of SAR modelling work by the Health Protection Agency in the UK. The paper addresses SAR modelling for non-uniform RF exposure conditions. When an antenna is located clo...

2009-04-30T23:59:59.000Z

323

Geothermal reservoir engineering code: comparison and validation  

DOE Green Energy (OSTI)

INTERCOMP has simulated six geothermal reservoir problems. INTERCOMP's geothermal reservoir model was used for all problems. No modifications were made to this model except to provide tabular output of the simulation results in the units used in RFP No. DE-RP03-80SF-10844. No difficulty was encountered in performing the problems described herein, although setting up the boundary and grid conditions exactly as specified were sometimes awkward, and minor modifications to the grid system were necessitated. The results of each problem are presented in tabular and (for many) graphical form.

Not Available

1981-02-27T23:59:59.000Z

324

Neutrino-Accelerated Hot Hydrogen Burning  

E-Print Network (OSTI)

We examine the effects of significant electron anti-neutrino fluxes on hydrogen burning. Specifically, we find that the bottleneck weak nuclear reactions in the traditional pp-chain and the hot CNO cycle can be accelerated by anti-neutrino capture, increasing the energy generation rate. We also discuss how anti-neutrino capture reactions can alter the conditions for break out into the rp-process. We speculate on the impact of these considerations for the evolution and dynamics of collapsing very- and super- massive compact objects.

Chad T. Kishimoto; George M. Fuller

2006-06-23T23:59:59.000Z

325

Khesbn no.109 - Spring 1987 - Journal  

E-Print Network (OSTI)

l! )b J1D n))2 ,'1 tlsn DbND rtD ']uu N 'rts! 'lBr ''t p:3;r11:1grr 1y:rp4ry)ry1i 1y .51! l:rTD yltrytfyn yEbrtNt l:yrrgpbN tN tyT tt g'tNl ''tjy b:rtD Jui :lt DllD l'D )Sl l']sD

Admin, LAYCC

1987-01-01T23:59:59.000Z

326

Projective Plane And Planar Quantum Codes  

E-Print Network (OSTI)

Cellulations of the projective plane RP 2 define single qubit topological quantum error correcting codes since there is a unique essential cycle in H 1 (RP 2 ; Z 2 ). We construct three of the smallest such codes, show they are inequivalent, and identify one of them as Shor's original 9 qubit repetition code. We observe that Shor's code can be constructed in a planar domain and generalize to planar constructions of higher genus codes for multiple qubits. PACS numbers: 03.67.Lx, 89.70.+c, 89.80.+h. AMS subject classification: 94Bxx, 81P99, 57M20. KEY WORDS: topological code, quantum error correction, planar code. Projective plane and planar quantum codes Freedman & Meyer Kitaev has constructed a class of quantum error correcting codes using qubits arranged on the edges of square lattices embedded in the two dimensional torus [1]. While these toric codes are not particularly efficient---they do not come close to saturating the quantum Hamming bound [2]---they are nevertheless inte...

Michael H. Freedman; David A. Meyer

1998-01-01T23:59:59.000Z

327

NETL: NETL Solicitation 2006 Archive  

NLE Websites -- All DOE Office Websites (Extended Search)

6 Archive 6 Archive Fiscal Year 2006 Solicitations POSTED DATE SOLICITATION NUMBER SOLICITATION SUBJECT TITLE CLOSING DATE(S) DOE CONTACT 12/15/06 DE-PS26-07NT43066 Notice of Intent to Issue Funding Opportunity Announcement and Pre-Funding Opportuntity Announcement Conference CANCELLED D. Reese 11/03/06 DE-RP26-07NT42918 National Energy Technology Laboratory-Albany A-76 Competition Canceled M. DeStefano 07/10/06 DE-RI26-06NT05004 Modern Grid Initiative 08/30/06 P. Findle 04/28/06 DE-RP26-06NT42586 Architect/Engineer (A/E) Services 06/01/06 J. Saunders 04/19/06 DE-PS26-06NT42770 Clean Cities Transportation Sector Petroleum Reduction Technologies Commercial Deployment 06/13/06 J. Collins 03/21/06 DE-PS26-06NT42837 Building Technologies State Energy Outreach and Deployment State Energy Program (SEP) Special Projects

328

Testing the mirror world hypothesis for the close-in extrasolar planets  

E-Print Network (OSTI)

Because planets are not expected to be able to form close to stars due to the high temperatures, it has been suggested that the observed close orbiting ($\\sim 0.05$ AU) large mass planets ($\\sim M_J$) might be mirror worlds -- planets composed predominately of mirror matter. The accretion of ordinary matter onto the mirror planet (from e.g. the solar wind from the host star) will make the mirror planet opaque to ordinary radiation with an effective radius $R_p$. It was argued in a previous paper, astro-ph/0101055, that this radius was potentially large enough to explain the measured size of the first transiting close-in extrasolar planet, HD209458b. Furthermore, astro-ph/0101055, made the rough prediction: $R_p \\propto \\sqrt{{T_s \\over M_p}}$, where $T_s$ is the surface temperature of the ordinary matter in the mirror planet and $M_p$ is the mass of the planet (the latter dependence being the more robust prediction). We compare this prediction with the recently discovered transiting planets, OGLE-TR-56b and OGLE-TR-113b.

R. Foot

2004-06-10T23:59:59.000Z

329

Observing the Galaxy's massive black hole with gravitational wave bursts  

E-Print Network (OSTI)

An extreme-mass-ratio burst (EMRB) is a gravitational wave signal emitted when a compact object passes through periapsis on a highly eccentric orbit about a much more massive object, in our case a stellar mass object about a 10^6 M_sol black hole. EMRBs are a relatively unexplored means of probing the spacetime of massive black holes (MBHs). We conduct an investigation of the properties of EMRBs and how they could allow us to constrain the parameters, such as spin, of the Galaxy's MBH. We find that if an EMRB event occurs in the Galaxy, it should be detectable for periapse distances r_p < 65 r_g for a \\mu = 10 M_sol orbiting object, where r_g = GM/c^2 is the gravitational radius. The signal-to-noise ratio scales as \\rho ~ -2.7 log(r_p/r_g) + log(\\mu/M_sol) + 4.9. For periapses r_p < 10 r_g, EMRBs can be informative, and provide good constraints on both the MBH's mass and spin. Closer orbits provide better constraints, with the best giving accuracies of better than one part in 10^4 for both the mass and ...

Berry, C P L

2012-01-01T23:59:59.000Z

330

Low doses of neutrons induce changes in gene expression  

SciTech Connect

Studies were designed to identify genes induced following low-dose neutron but not following {gamma}-ray exposure in fibroblasts. Our past work had shown differences in the expression of {beta}-protein kinase C and c-fos genes, both being induced following {gamma}-ray but not neutron exposure. We have identified two genes that are induced following neutron, but not {gamma}-ray, exposure: Rp-8 (a gene induced by apoptosis) and the long terminal repeat (LTR) of the human immunodeficiency (HIV). Rp-8 mRNA induction was demonstrated in Syrian hamster embryo fibroblasts and was found to be induced in cells exposed to neutrons administered at low (0.5 cGy/min) and at high dose rate (12 cGy/min). The induction of transcription from the LTR of HIV was demonstrated in HeLa cells bearing a transfected construct of the chloramphenicol acetyl transferase (CAT) gene driven by the HIV-LTR promoter. Measures of CAT activity and CAT transcripts following irradiation demonstrated an unresponsiveness to {gamma} rays over a broad range of doses. Twofold induction of the HIV-LTR was detected following neutron exposure (48 cGy) administered at low (0.5 cGy/min) but not high (12 cGy/min) dose rates. Ultraviolet-mediated HIV-LTR induction was inhibited by low-dose-rate neutron exposure.

Woloschak, G.E.; Chang-Liu, C.M. [Argonne National Lab., IL (United States); Panozzo, J.; Libertin, C.R. [Loyola Univ., Maywood, IL (United States)

1993-06-01T23:59:59.000Z

331

Low doses of neutrons induce changes in gene expression  

SciTech Connect

Studies were designed to identify genes induced following low-dose neutron but not following [gamma]-ray exposure in fibroblasts. Our past work had shown differences in the expression of [beta]-protein kinase C and c-fos genes, both being induced following [gamma]-ray but not neutron exposure. We have identified two genes that are induced following neutron, but not [gamma]-ray, exposure: Rp-8 (a gene induced by apoptosis) and the long terminal repeat (LTR) of the human immunodeficiency (HIV). Rp-8 mRNA induction was demonstrated in Syrian hamster embryo fibroblasts and was found to be induced in cells exposed to neutrons administered at low (0.5 cGy/min) and at high dose rate (12 cGy/min). The induction of transcription from the LTR of HIV was demonstrated in HeLa cells bearing a transfected construct of the chloramphenicol acetyl transferase (CAT) gene driven by the HIV-LTR promoter. Measures of CAT activity and CAT transcripts following irradiation demonstrated an unresponsiveness to [gamma] rays over a broad range of doses. Twofold induction of the HIV-LTR was detected following neutron exposure (48 cGy) administered at low (0.5 cGy/min) but not high (12 cGy/min) dose rates. Ultraviolet-mediated HIV-LTR induction was inhibited by low-dose-rate neutron exposure.

Woloschak, G.E.; Chang-Liu, C.M. (Argonne National Lab., IL (United States)); Panozzo, J.; Libertin, C.R. (Loyola Univ., Maywood, IL (United States))

1993-01-01T23:59:59.000Z

332

BWR (boiling-water reactor) radiation control: In-plant demonstration at Vermont Yankee: Final report  

Science Conference Proceedings (OSTI)

Results of the RP1934 program, which was established by EPRI in 1981 to demonstrate the adequacy of BRAC program (RP819) principles for BWR radiation control at Vermont Yankee, are presented. Evaluations were performed of the effectiveness of optimization of purification system performance, control of feedwater dissolved oxygen concentrations, minimization of corrosion product and ionic transport, and improved startup, shutdown, and layup practices. The impact on shutdown radiation levels of these corrective actions was assessed based on extensive primary system radiation survey and component gamma scan data. Implementation of the BRAC recommendations was found to be insufficient to reduce the rate of activity buildup on out-of-core surfaces at Vermont Yankee, and additional corrective actions were found necessary. Specifically, replacement of cobalt-bearing materials in the control rod drive pins and rollers and feedwater regulating valves was pursued as was installation of electropolished 316 stainless steel during a recirculation piping replacement program. Aggressive programs to further reduce copper concentrations in the reactor water by improving condensate demineralizer efficiency and to minimize organic ingress to the power cycle by reducing organic concentrations in recycled radwaste also were undertaken. Evaluations of the impact on activity buildup of several pretreatment processes including prefilming in moist air, preexposure to high temperature water containing zinc, and electropolishing also were performed in a test loop installed in the reactor water cleanup system. A significant beneficial impact of electropolishing was shown to be present for periods up to 6000 hours.

Palino, G.F.; Hobart, R.L.; Sawochka, S.G.

1987-10-01T23:59:59.000Z

333

Journey to Flexible, Reliable, Laboratory Platform for Simultaneous Control of Multiple Reactive Power Producing Devices  

SciTech Connect

Herein is discussed the instrumentation and control requirements for achieving the goal of operating multiple Distributed Energy (DE) devices in parallel to regulate local voltage. The process for establishing the flexible laboratory control and data acquisition system that allows for the integration of multiple Distributed Energy (DE) devices in XXXX Laboratory's Distributed Energy - Communications and Controls Laboratory (DECC) is discussed. The DE devices control local distribution system voltage through dynamic reactive power production. Although original efforts were made to control the reactive power (RP) output using information from commercially available meters specifically designed for monitoring and analyzing electric power values, these "intelligent" meters did not provide the flexibility needed. A very flexible and capable real-time monitoring and control system was selected after the evaluation of various methods of data acquisition (DAQ) and control. The purpose of this paper is to describe the DAQ and controls system development. The chosen controller is a commercially available real-time controller from dSPACE. This controller has many excellent features including a very easy programming platform through Simulink and Matlab's Real Time Workshop. The dSPACE system proved to provide both the flexibility and expandability needed to integrate and control the RP producing devices under consideration. The desire was to develop controls with this flexible laboratory instrumentation and controls setup that could be eventually be included in an embedded controller on a DE device. Some experimental results are included that clearly show that some functional control strategies are currently being tested.

Foster, Jason [ORNL; Rizy, D Tom [ORNL; Kueck, John D [ORNL

2007-01-01T23:59:59.000Z

334

ac/dc power converter for batteries and fuel cells. Annual report  

SciTech Connect

The overall objective of the EPRI RP841-1 program is the design of an advanced power converter for use in both battery energy storage and fuel cell generation systems in the 1980's. This goal will be accomplished by expansion of United's existing FCG-1 fuel cell power conditioning inverter into a high-efficiency inverter--rectifier system employing improved commutation circuits and advanced (1980's) semiconductor devices capable of operating over wider dc voltage ranges. A separate but concurrent program for the U.S. Department of Energy (DOE) -- E(49-18)2122 -- is examining augmentation of the present FCG-1 inverter for operation as an inverter--rectifier with battery systems; feasibility and operating characteristics have been demonstrated. United's activities and accomplishments in the EPRI RP841-1 program include revision of the preliminary specification for ac/dc conversion equipment contained in the Statement of Work, survey of seven semiconductor manufacturers to project characteristics of 1980's thyristors, screening of fifteen commutation concepts and selection of the two most promising options for experimental evaluation, and modifications of existing experimental power pole hardware to evaluate the selected advanced commutation circuits. 34 figures, 3 tables.

Rosati, R.W. (ed.)

1978-08-01T23:59:59.000Z

335

Lab Spotlight: Sandia National Laboratory  

NLE Websites -- All DOE Office Websites (Extended Search)

Sandia National Laboratories Sandia National Laboratories Illustration of integrated circuit Figure 1. An application-specific integrated circuit being developed for advanced artificial retinas. Click on image to enlarge. Microscale Enablers More advanced artificial retinas are relying on miniaturized electronics for processing incoming images and activating the corresponding electrodes to communicate with retinal cells and ultimately the brain. The goal of these devices, being developed through a U.S. Department of Energy (DOE) collaboration, is to continually improve their visual resolution so that implanted individuals eventually will be able to read large print, recognize faces, and move about without aid. Sandia National Laboratories' expertise in the development, fabrication, and production

336

Lipid Metabolism, Gene Expression, Substrate Oxidation, and Meat Quality of Growing-finishing Pigs Supplemented with Conjugated Linoleic Acid and Arginine  

E-Print Network (OSTI)

We hypothesized that supplementation of dietary conjugated linoleic acid (CLA) and arginine singly or in combination would increase animal performance and meat quality by decreasing adiposity and increasing lean mass in growing-finishing pigs. Sixteen pigs (80 kg) were assigned to four treatments in a 2 x 2 factorial design, differing in dietary fatty acid and amino acid composition [control: 2.05% alanine (isonitrogenous control) plus 1% canola oil (lipid control); CLA: 2.05% alanine + 1% CLA; arginine: 1% arginine + 1% canola oil; arginine + CLA: 1% arginine + 1 CLA]. Preliminary tests indicated that up to 2% arginine was acceptable without interfering with lysine absorption. Pigs were allowed to feed free choice until reaching 110 kg. There were no significant differences across treatments in feed intake, weight gain, or feed efficiency. CLA tended to decrease carcass length (P = 0.06), whereas backfat thickness tended to be greater in pigs supplemented with arginine (P = 0.08). Arginine decreased muscle pH at 45 min postmortem (P = 0.001) and tended to increase lightness of muscle at 24 h postmortem (P = 0.07). CLA supplementation increased the concentrations of trans-isomers of 18:1 (P = 0.001) and SFA (P = 0.01) in s.c. and r.p. adipose tissue. CLA supplementation increased palmitate incorporation into total lipids in longissimus muscle (P = 0.01). Glucose oxidation to CO? in r.p. and s.c. adipose tissue were greater in pigs supplemented with CLA in the absence or presence of arginine (P = 0.03 and P = 0.04, respectively). The volume of s.c. adipocytes in s.c. and r.p. adipose tissues was greater in pigs supplemented with CLA, arginine, or CLA plus arginine than in control pigs (P = 0.001). Neither CLA nor arginine affected the expression of PGC-1[alpha],AMPK, mTOR, CPT-1A, FAS, or SCD (P > 0.05) in any tissues. We conclude that there was no significant interaction between arginine and CLA. Supplementary CLA or arginine to finishing-growing pigs did not modulate growth performance and did not reduce adiposity. CLA increased intramuscular fat content without deteriorating meat quality traits and increased saturated fatty acids and substrate oxidation in adipose tissues. In the presence of 1% of canola oil or CLA in the diet, arginine has the potential to deteriorate meat quality by reducing early postmortem pH and by increasing carcass fatness.

Go, Gwang-Woong, 1979-

2010-12-01T23:59:59.000Z

337

Integration of the reliability of passive system in probabilistic safety assessment  

SciTech Connect

Probability Safety Assessment (PSA) of nuclear power plants has demonstrated its efficiency in decision-making process. But the treatment in PSA of safety passive systems, specially those implementing moving working fluid, is a difficult task because in addition to the mechanical failures of components, the failure of the physical process (e.g. natural circulation) has to be considered. The difficulty in the evaluation of the failure risk of the physical phenomenon lies in the great number of parameters that must be taken into account, in their associated uncertainties and in the limitations of physical modelling. We can note that in the existing PSA of future reactors equipped with passive systems, this risk of the physical process failure due to the uncertainties, is not at all taken into account. In this paper, we present a methodology to evaluate this risk of failure and to include it in a PSA. This evaluation is obtained by uncertainty analyses on thermalhydraulic calculations. As an example, a simplified PSA was carried out on a fictive reactor with two types of safety passive systems both in the primary circuit: Residual Passive heat Removal system (RP2) and a safety injection system consisting in accumulators and discharge lines equipped with check valves. An accidental scenario has been analysed, starting with loss of electrical supply when the reactor is at full power. The failure analyses performed on this reactor have allowed the characterisation of the technical failures (on RP2 valves, tubes in RP2 exchanger and safety injection check valves) and the ranges of variation of uncertain parameters which influence the physical process. The resulting accidental scenario is presented in the form of a simplified event tree. The majority of the sequences of this event tree have been analysed by deterministic evaluations with envelope values of the uncertain parameters. For some sequences where the definition of envelope cases was impossible, basic events corresponding to the failure of the physical process have been added and uncertainty analyses have been performed to evaluate the corresponding probability of failure. For this purpose the thermal-hydraulic CATHARE code has been coupled to a Monte-Carlo simulation modulus. The failure probabilities obtained by these reliability analyses have been integrated in the corresponding sequences. This methodology allows the probabilistic evaluation of the influence of the passive system on an accidental scenario and could be used to test the interest to replace an active system by a passive system on specific situations. (authors)

Marques, M. [Commissariat a l'Energie Atomique (CEA), Building 212, Centre de Cadarache, 13108 Saint-Paul-Les-Durance Cedex (France); Pignatel, J.F.; Saignes, P.; Devictor, N.; La Lumia, V.; Mercier, S

2004-07-01T23:59:59.000Z

338

On the design and analysis of the software and data architecture of ROI-based image retrieval system  

E-Print Network (OSTI)

Content-based Image Retrieval (CBIR) has been widely used in many areas such as crime prevention, the military, web searching, intellectual property, etc. The technology related to CBIR has been continuously developed, such as multi-dimensional indexing and features extraction algorithms. However, some issues still need to be resolved such as high-level semantics of images, human in the loop, etc. The application of CBIR in many professional areas is still under development. Thus further study and research are necessary and important to address those problems. In ophthalmology, physicians often need to compare retinal images in their collections with common properties for a specific purpose, or find similar Region of Interests (ROI) in different images, which is very useful as reference for current diagnostic. Although much effort in the pattern recognition has been explored and shown to be helpful, specific application for retinal images retrieval is still in its infancy. In this thesis, we propose a ROI (Region of Interests)-based image retrieval system, which supports finding similar ROI in the database based on the ROI content. After studying some CBIR techniques and reviewing several CBIR systems we proposed a Multi-layered 2D Matrix Indexing Scheme, which allows for retrieval of the similar ROIs from the database. The prototype architecture is presented and the data structure of the software system is discussed.

Bu, Junjie

2003-01-01T23:59:59.000Z

339

Surveillance Guides - RPS 11.2 Radiological Work Practices  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

RADIOLOGICAL WORK PRACTICES RADIOLOGICAL WORK PRACTICES 1.0 Objective The objective of this surveillance is to evaluate the practices of workers performing tasks in radiological controlled areas to ensure that these practices protect the safety and health of the workers and comply with DOE requirements. 2.0 References 2.1 10 CFR 835, Occupational Radiation Protection 2.2 DOE/EH-0256T, rev. 1, Radiological Control Manual 3.0 Requirements Implemented This surveillance is conducted to implement requirement RP-0024 from the RL S/RID. This requirement comes from the Radiological Control Manual. 4.0 Surveillance Activities The Facility Representative performs the following activities to evaluate the effectiveness of work practices by contractor personnel in minimizing exposure to radiological hazards.

340

E:\CO2\wp_files\test_2.PDF  

Office of Scientific and Technical Information (OSTI)

DOE/ARC-2000-008 CARBON DIOXIDE SEQUESTRATION BY DIRECT MINERAL CARBONATION WITH CARBONIC ACID March 6-9, 2000 Proceedings of the 25 th International Technical Conf. On Coal Utilization & Fuel Systems, Coal Technology Assoc., Clear Water, FL by W.K. O'Connor, D.C. Dahlin, D.N. Nilsen, R.P. Walters and P.C. Turner Albany Research Center Albany, Oregon CARBON DIOXIDE SEQUESTRATION BY DIRECT MINERAL CARBONATION WITH CARBONIC ACID W. K. O'Connor, D. C. Dahlin, D. N. Nilsen, R. P. Walters, and P. C. Turner Albany Research Center Office of Fossil Energy U.S. Department of Energy ABSTRACT The Albany Research Center (ARC) of the U.S. Dept. of Energy (DOE) has been conducting a series of mineral carbonation tests at its Albany, Oregon, facility over the past 2 years as part of a Mineral

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We encourage you to perform a real-time search of NLEBeta
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341

Recent Publications | Advanced Photon Source  

NLE Websites -- All DOE Office Websites (Extended Search)

Entries in the APS Publications Database for the week ending 01.05.2014 Entries in the APS Publications Database for the week ending 01.05.2014 This list of entries in the APS Publications Database includes Journal Articles (9,003), Conference Proceedings (7), Books (4), and Book Chapters (76), and Dissertations (0). This list of entries in the APS Publications Database does not include abstracts, invited talks, awards, magazine articles, or patents. For the complete list, search the APS Publications Database. Inquiries about or submissions to the publications database should be directed to apspubs@aps.anl.gov. Journal Article Z. Aabdin, N. Peranio, O. Eibl, Tö W. llner, K. Nielsch, D. Bessas, R.P. Hermann, M. Winkler, Kö J. nig, Bö H. ttner, V. Pacheco, J. Schmidt, A. Hashibon, Elsä C. sser, Nanostructure, Excitations, and Thermoelectric

342

Record of Decision and Floodplain Statement of Findings for the Trinity Public Utilities District Direct Interconnection Project (DOE/EIS-0389)  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

8, 2008 8, 2008 / Notices Applicants: Trailblazer Pipeline Company. Description: Trailblazer Pipeline Company submits Original Sheet 0 and 1 et al. to FERC Gas Tariff, Fourth Revised Volume 1, to be effective 12/28/ 07. Filed Date: 01/18/2008. Accession Number: 20080123-0026. Comment Date: 5 p.m. Eastern Time on Wednesday, January 30, 2008. Docket Numbers: RP08-169-000. Applicants: Dominion Cove Point LNG, LP. Description: Dominion Cove Point LNG, LP submits Eighth Revised Sheet 11 to its FERC Gas Tariff, Original Volume 1, to be effective 2/17/08. Filed Date: 01/18/2008. Accession Number: 20080123-0019. Comment Date: 5 p.m. Eastern Time on Wednesday, January 30, 2008. Any person desiring to intervene or to protest in any of the above proceedings must file in accordance with Rules 211

343

The Environmental Style: Writing Environmental Assessments And Impact Statements  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

STYLE STYLE WRITING ENVIRONMENTAL ASSESSMENTS AND IMPACT STATEMENTS R.P. Detwiler NNSA Office of General Counsel October 2005 In his introduction to William Strunk's classic on writing, The Elements of Style, E. B. White described the plight of those who read many of our NEPA documents: Will [Strunk] felt that the reader was in serious trouble most of the time, a man foundering in a swamp, and that it was the duty of anyone attempting to write English to drain this swamp quickly and get this man on dry ground, or at least throw him a rope. In revising text, I have tried to hold steadily in mind a belief of his, this concern for the bewildered reader. The Department and its contractors need to hold in their minds the women and men - decision makers, citizens, regulators and judges - who slog through our environmental

344

Research Highlight  

NLE Websites -- All DOE Office Websites (Extended Search)

Parameterizing the Ice Fall Speed in Climate Models: Results from TC4 and Parameterizing the Ice Fall Speed in Climate Models: Results from TC4 and ISDAC Download a printable PDF Submitter: Mitchell, D. L., Desert Research Institute Mishra, S., NOAA - Coop. Inst. for Mesoscale Meteorological Studies Area of Research: General Circulation and Single Column Models/Parameterizations Working Group(s): Cloud Life Cycle, Cloud-Aerosol-Precipitation Interactions Journal Reference: Mitchell DL, S Mishra, and RP Lawson. 2011. "Representing the ice fall speed in climate models: Results from Tropical Composition, Cloud and Climate Coupling (TC4) and the Indirect and Semi-Direct Aerosol Campaign (ISDAC)." Journal of Geophysical Research - Atmospheres, 116, D00T03, doi:10.1029/2010JD015433. Relationship between De and Vm for all tropical cirrus cloud types (solid

345

Research Highlight  

NLE Websites -- All DOE Office Websites (Extended Search)

How Aerosols Affect Cloud Properties in Arctic Mixed-Phase Stratocumulus How Aerosols Affect Cloud Properties in Arctic Mixed-Phase Stratocumulus Download a printable PDF Submitter: McFarquhar, G., University of Illinois, Urbana Area of Research: Cloud-Aerosol-Precipitation Interactions Working Group(s): Cloud-Aerosol-Precipitation Interactions Journal Reference: Jackson RC, GM McFarquhar, AV Korolev, ME Earle, PS Liu, RP Lawson, S Brooks, M Wolde, A Laskin, and M Freer. 2012. "The dependence of ice microphysics on aerosol concentration in arctic mixed-phase stratus clouds during ISDAC and M-PACE." Journal of Geophysical Research - Atmospheres, 117, D15207, doi:10.1029/2012JD017668. Cloud mean ice crystal concentration Nice(D ≥ 50 micrometers) versus mean aerosol concentration (NPCASP) above cloud for all 41 vertical profiles

346

Natural and Enhanced Attenuation of Soil and Groundwater at the Monument  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Natural and Enhanced Attenuation of Soil and Groundwater at the Natural and Enhanced Attenuation of Soil and Groundwater at the Monument Valley, Arizona, DOE Legacy Waste Site Natural and Enhanced Attenuation of Soil and Groundwater at the Monument Valley, Arizona, DOE Legacy Waste Site Paper presented at the Waste Management 2010 Conference. March 7 through March 10, 2010, Phoenix, Arizona. W.J.Waugh, D.E. Miller, S.A. Morris, L.R. Sheader, E.P. Glenn, D. Moore, K.C. Carroll, L. Benally, M. Roanhorse, R.P. Bush Natural and Enhanced Attenuation of Soil and Groundwater at the Monument Valley, Arizona, DOE Legacy Waste Site More Documents & Publications EA-1313: Final Environmental Assessment Applied Science and Technology Task Order Fiscal Year 2009 Year-End Summary Report Applied Science and Technology Task Order Fiscal Year 2008 Year-End Summary

347

SR0105  

NLE Websites -- All DOE Office Websites (Extended Search)

4, 2001 4, 2001 Media Contact: Julie Petersen (803) 725-2889 Doe Announces Availability Of Draft RFP On Salt Waste Processing Facility Flag Ribbon Art Aiken, SC; May 24, 2001 -- Today the Department of Energy (DOE) Savannah River Operations Office (SR) announced in the Commerce Business Daily the availability of the Draft Request for Proposals (RFP) for the acquisition of services to design, construct, and commission a facility to process the salt fraction of high-level radioactive waste currently stored in underground tanks at the Savannah River Site. DOE-SR is seeking industry and stakeholder comments on the draft RFP. The Draft Request for Proposals, DE-RP09-01SR22210, Salt Waste Processing Facility, is available at the DOE Public Reading Room at the Gregg-Graniteville Library at the University of South Carolina-Aiken campus in Aiken, South Carolina, or Internet-accessible at www.e-center.doe.gov.

348

S0 STATEMENT OF CONSIDERATIONS REQUEST BY GENERAL MOTORS CORPORATION (GM) FOR AN  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

S0 S0 STATEMENT OF CONSIDERATIONS REQUEST BY GENERAL MOTORS CORPORATION (GM) FOR AN ADVANCE WAIVER OF DOMESTIC AND FOREIGN RIGHTS TO INVENTIONS MADE UNDER COOPERATIVE AGREEMENT NUMBER DE-FC04-03AL67635, DOE WAIVER NO. W(A) 03-019. The Petitioner, GM, has requested a waiver of all domestic and foreign patent rights to inventions that GM may conceive or first actually reduce to practice in the course of GM's work under Cooperative Agreement Number DE-FC04-03AL67635 entitled "Innovative Emission Control Device." The petition was originally submitted as part of a response to a funding proposal - known at that time as DE-RP04-01AL67057. The work to be done under the cooperative agreement will be the development of new microwave soot combustion components in compression-ignition, direct-injection (CIDI)

349

Data:06d05314-324c-4ece-a8ad-07943d83eefb | Open Energy Information  

Open Energy Info (EERE)

5314-324c-4ece-a8ad-07943d83eefb 5314-324c-4ece-a8ad-07943d83eefb No revision has been approved for this page. It is currently under review by our subject matter experts. Jump to: navigation, search Loading... 1. Basic Information 2. Demand 3. Energy << Previous 1 2 3 Next >> Basic Information Utility name: City of Richmond, Indiana (Utility Company) Effective date: End date if known: Rate name: Street Lighting- Underground Service- 4-400 Watt Mercury Vapor Sector: Lighting Description: AVAILABILITY Available to any customer requesting the Utility to furnish pendant type fixtures for the lighting of railroad crossings or streets and alleys. Source or reference: http://www.rp-l.com/commercialrates.php Source Parent: Comments Applicability Demand (kW) Minimum (kW): Maximum (kW): History (months):

350

CX-008630: Categorical Exclusion Determination | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

0: Categorical Exclusion Determination 0: Categorical Exclusion Determination CX-008630: Categorical Exclusion Determination Surface Water and Groundwater Sampling Pen Branch Floodplain near Chemicals Metals and Pesticides Pits CX(s) Applied: B3.1 Date: 06/07/2012 Location(s): South Carolina Offices(s): Savannah River Operations Office In accordance with the Effectiveness Monitoring Plan for the Chemicals Metals and Pesticides (CMP) Pits (WSRC-RP-2005-4077) Surface Water in Pen Branch must be sampled semi-annually in order to evaluate the Monitored Natural Attenuation (MNA) remedy for the volatile organic compounds (VOC) plume associated with the CMP Pits. Sampling in and beneath the stream are necessary to identify the VOC plume fringe from CMP Pits. Sampling may be conducted by Historically Black Colleges and Universities (HBCU) students.

351

Water-Balance Cover Performance  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

0, 2010, Phoenix, AZ 0, 2010, Phoenix, AZ Natural and Enhanced Attenuation of Soil and Groundwater at the Monument Valley, Arizona, DOE Legacy Waste Site-10281 W.J. Waugh, D.E. Miller, S.A. Morris, and L.R. Sheader S.M. Stoller Corporation, Grand Junction, CO E.P. Glenn, D. Moore, and K.C. Carroll University of Arizona, Tucson, AZ L. Benally and M. Roanhorse Navajo Nation, Window Rock, AZ R.P. Bush U.S. Department of Energy, Grand Junction, CO ABSTRACT The U.S. Department of Energy (DOE), the Navajo Nation, and the University of Arizona are exploring natural and enhanced attenuation remedies for groundwater contamination at a former uranium-ore processing site near Monument Valley, Arizona. DOE removed radioactive tailings from the Monument Valley site in 1994. Nitrate and ammonium, waste products of the milling process, remain in an alluvial

352

arch layout 11.21.98  

NLE Websites -- All DOE Office Websites (Extended Search)

0.jpg 0.jpg Environmental Quality IMAGE imgs/esl3121.jpg There have been unsubstantiatedclaims that daylighting benefits the health, satisfaction, and even productivity of humans. Both daylighting prototypes were designed to improve comfort as well as increase energ y-efficiency. With this research, we beg an the process of quantifying the qualitative benefits of dynamic andlight-redirecting window/lighting systems using simulationtools, reduced-scalefield tests,andfull-scaledemonstrations. Some of our arguments for qualityimprovements comparedto conventional systems were madebased on meeting well-known design constraints,thresholds setby experimentalfield data (e.g., glare or thermal comfort indices), or industry guidelines (e.g., IES RP-1 for visualcomfort). These methods only partiallydescribe the fitness of a

353

Research Highlight  

NLE Websites -- All DOE Office Websites (Extended Search)

Data from Saharan Dust Storm Reveal Model Deficiencies Data from Saharan Dust Storm Reveal Model Deficiencies Submitter: McFarlane, S. A., U.S. Department of Energy Area of Research: Radiation Processes Working Group(s): Radiative Processes Journal Reference: Slingo, A., T.P. Ackerman, R.P. Allan, E.I. Kassianov, S.A. McFarlane, G.J. Robinson, J.C. Barnard, M.A. Miller, J.E. Harries, J.E. Russell , S. Dewitte, 2006: Observations of the impact of a major Saharan dust storm on the Earth's radiation budget. Geophys. Res. Lett., 33, L24817, doi:10.1029/2006GL027869. In March 2006, the ARM Mobile Facility recorded the strongest Saharan dust storm to reach the Niamey area in two years. The storm lasted several days, and visibility was reduced to 15 percent of normal. Observations (solid lines and star symbols) and results from two models

354

Coupling Air Flow Models to Load/Energy Models and Implications for  

NLE Websites -- All DOE Office Websites (Extended Search)

Coupling Air Flow Models to Load/Energy Models and Implications for Coupling Air Flow Models to Load/Energy Models and Implications for Envelope Component Testing and Modeling Speaker(s): Brent Griffith Date: July 30, 2002 - 12:00pm Location: Bldg. 90 Seminar Host/Point of Contact: Dariush Arasteh Air models allow accounting for air temperature variations within a thermal zone or along the surface of an envelope component. A recently completed ASHRAE research project (RP-1222) produced a source code toolkit focused on coupling airflow models to load routines typical of whole building energy simulation. The two modeling domains are computed separately (and iteratively) with relevant temperature boundary conditions passed back and forth. One of the air models in the toolkit is a new contribution to crude/fast airflow modeling that is based on solving the Euler equation

355

LTS-O&M Selected Publications | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Selected Publications Selected Publications LTS-O&M Selected Publications Waugh, W.J., E.P. Glenn, P.H. Charley, B. Maxwell, and M.K. O'Neill. 2011. Helping Mother Earth Heal: Diné College and Enhanced Natural Attenuation Research at U.S. Department of Energy Uranium Processing Sites on Navajo Land. In: Burger, J. (ed.) Stakeholders and Scientists: Achieving Implementable Solutions to Energy and Environmental Issues. Springer, New York, New York. Benson, C.H., W.J. Waugh, W.H. Albright, and R.P. Bush, 2011. "Design and Installation of a Disposal Cell Cover Renovation Field Experiment, Proceedings of Waste Management 2011 Symposium, Phoenix, AZ. Dayvault, J., S. Morrison, and J. Waugh, 2011. "Overview of U.S. Department of Energy Office of Legacy Management Applied Science and

356

C/'  

Office of Legacy Management (LM)

C/' C/' . ZTW ,990 EM-421 XL A ) XL II, 7131 , b=4, OH 27 - IL id, MJi3, p-- 27 RJttxRP I=1 L-E Public Access to FUSRAP Elimination Reports John Carter, AD-234.1 I am attaching reports for the evaluation and elimination of a number of sites from the Department's Formerly Utilized Sites Remedial Action Program (FUSRAP). Please enter this material into the Public Reading Room at the Forrestal Building. This process completes FUSRAP activities at these facilities. Our protocol requires that these FUSRAP records be available in the Public Reading Room for at least 3 years; however, if possible, they should be retained for 5 years. This package contains information supporting the elimination of the following facilities: Former Herring-Hall-Marvin Safe Company

357

Examination and experimental constraints of the stellar reaction rate factor $N_A $ of the $^{18}$Ne($?$,$p$)$^{21}$Na reaction at temperatures of X-Ray Bursts  

E-Print Network (OSTI)

The $^{18}$Ne($\\alpha$,$p$)$^{21}$Na reaction is one key for the break-out from the hot CNO-cycles to the $rp$-process. Recent papers have provided reaction rate factors $N_A $ which are discrepant by at least one order of magnitude. The compatibility of the latest experimental results is tested, and a partial explanation for the discrepant $N_A$ is given. A new rate factor is derived from the combined analysis of all available data. The new rate factor is located slightly below the higher rate factor by Matic {\\it et al.}\\ at low temperatures and significantly below at higher temperatures whereas it is about a factor of five higher than the lower rate factor recently published by Salter {\\it et al.}

P. Mohr; A. Matic

2013-03-06T23:59:59.000Z

358

The Complexity of Approximating Bounded-Degree Boolean #CSP  

E-Print Network (OSTI)

The degree of a CSP instance is the maximum number of times that a variable may appear in the scope of constraints. We consider the approximate counting problem for Boolean CSPs with bounded-degree instances for constraint languages containing the two unary constant relations {0} and {1}. When the maximum degree is at least 25 we obtain a complete classification of the complexity of this problem. It is exactly solvable in polynomial-time if every relation in the constraint language is affine. It is equivalent to the problem of approximately counting independent sets in bipartite graphs if every relation can be expressed as conjunctions of {0}, {1} and binary implication. Otherwise, there is no FPRAS unless NP=RP. For lower degree bounds, additional cases arise in which the complexity is related to the complexity of approximately counting independent sets in hypergraphs.

Dyer, Martin; Jalsenius, Markus; Richerby, David

2009-01-01T23:59:59.000Z

359

The Complexity of Approximating Bounded-Degree Boolean #CSP (Extended Abstract)  

E-Print Network (OSTI)

The degree of a CSP instance is the maximum number of times that a variable may appear in the scope of constraints. We consider the approximate counting problem for Boolean CSPs with bounded-degree instances, for constraint languages containing the two unary constant relations {0} and {1}. When the maximum degree is at least 25 we obtain a complete classification of the complexity of this problem. It is exactly solvable in polynomial-time if every relation in the constraint language is affine. It is equivalent to the problem of approximately counting independent sets in bipartite graphs if every relation can be expressed as conjunctions of {0}, {1} and binary implication. Otherwise, there is no FPRAS unless NP=RP. For lower degree bounds, additional cases arise in which the complexity is related to the complexity of approximately counting independent sets in hypergraphs.

Dyer, Martin E; Jalsenius, Markus; Richerby, David

2010-01-01T23:59:59.000Z

360

A Z2 Structure in the Configuration Space of Yang-Mills Theories  

E-Print Network (OSTI)

We argue for the presence of a Z2 topological structure in the space of static gauge-Higgs field configurations of SU(2n) and SO(2n) Yang-Mills theories. We rigorously prove the existence of a Z2 homotopy group of mappings from the 2-dim. projective sphere RP 2 into SU(2n)/Z2 and SO(2n)/Z2 Lie groups respectively. Consequently the symmetric phase of these theories admits infinite surfaces of odd-parity static and unstable gauge field configurations which divide into two disconnected sectors with integer Chern-Simons numbers n and n + 1/2 respectively. Such a Z2 structure persists in the Higgs phase of the above theories and accounts for the existence of CS = 1/2 odd-parity saddle point solutions to the field equations which correspond to spontaneous symmetry breaking mass scales. 1

Minos Axenides; Andrei Johansen; Jesper Mller

1995-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "retinitis pigmentosa rp" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


361

Colloidal templating at a cholesteric - oil interface: Assembly guided by an array of disclination lines  

E-Print Network (OSTI)

We simulate colloids (radius $R \\sim 1\\mu$m) trapped at the interface between a cholesteric liquid crystal and an immiscible oil, at which the helical order (pitch p) in the bulk conflicts with the orientation induced at the interface, stabilizing an ordered array of disclinations. For weak anchoring strength W of the director field at the colloidal surface, this creates a template, favoring particle positions eitheron top of or midway between defect lines, depending on $\\alpha = R/p$. For small $\\alpha$, optical microscopy experiments confirm this picture, but for larger $\\alpha$ no templating is seen. This may stem from the emergence at moderate W of a rugged energy landscape associated with defect reconnections.

J. S. Lintuvuori; A. C. Pawsey; K. Stratford; M. E. Cates; P. S. Clegg; D. Marenduzzo

2013-11-08T23:59:59.000Z

362

An Overview of Geometry Representation in Monte Carlo Codes  

National Nuclear Security Administration (NNSA)

Geometry Representation Geometry Representation in Monte Carlo Codes R.P. Kensek, * B.C. Franke, * T.W. Laub * , L.J. Lorence, * M. R. Martin, * S. Warren † * Sandia National Laboratories, P.O. Box 5800, MS 1179, Albuquerque, NM 87185 † Kansas State University, Manhattan, KS 66506 Geometry representations in production Monte Carlo radiation transport codes used for linear-transport simulations are traditionally limited to combinatorial geometry (CG) topologies. While CG representations of input geometries are efficient to query, they are difficult to construct. In the Integrated-TIGER-Series (ITS) Monte Carlo code suite, a new approach for radiation transport geometry engines has been implemented that allows for Computer Aided Design (CAD), facetted approximations, and other geometry types to simultaneously define an input geometry.

363

Slide 1  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Electric Vehicles Forum Electric Vehicles Forum Beijing, China Economics of EV Market/Future of EV Industry Brian P. Wynne President September 29, 2009 Officers: RP Associates EDTA Board of Directors The Future of Electrified Transportation ● Vehicles and fuels need to develop in parallel. ● Vehicle electrification is well underway. Vehicle Perspective Plug-in Hybrid Vehicles: 2009 Fisker Karma S Plug-in Hybrid 2009 Toyota Plug-in Hybrid 2011 BYD F3DM Plug-in Hybrid 2012 Bright Automotive IDEA Plug-in Hybrid 2012 Ford Plug-in Hybrid 2012 Volvo Plug-in Hybrid Hybrid Electric Vehicles: 2010 Mercedes S400 Hybrid 2010 Ford Fusion Hybrid 2010 Honda Insight Hybrid 2010 Hyundai-Kia Hybrid 2010 Lexus HS 250h 2010 Mercedes E Class Hybrid 2010 Porsche Cayenne S Hybrid 2010 Toyota Camry Hybrid 2010 Toyota Prius Hybrid

364

Property:Geothermal/AboutArea | Open Energy Information  

Open Energy Info (EERE)

AboutArea AboutArea Jump to: navigation, search Property Name Geothermal/AboutArea Property Type Text Description About the Area Pages using the property "Geothermal/AboutArea" Showing 18 pages using this property. A A 3D-3C Reflection Seismic Survey and Data Integration to Identify the Seismic Response of Fractures and Permeable Zones Over a Known Geothermal Resource at Soda Lake, Churchill Co., NV Geothermal Project + Churchill County, NV Alum Innovative Exploration Project Geothermal Project + Alum geothermal project is located in Nevada ~150 miles SE of Reno. It consists of federal geothermal leases that are 100% owned by SGP. Application of 2D VSP Imaging Technology to the Targeting of Exploration and Production Wells in a Basin and Range Geothermal System Humboldt House-Rye Patch Geothermal Area Geothermal Project + Humboldt House-Rye Patch (HH-RP) geothermal resource area

365

Data:0cec555c-6237-4cd1-931a-4d87b7a8618b | Open Energy Information  

Open Energy Info (EERE)

cec555c-6237-4cd1-931a-4d87b7a8618b cec555c-6237-4cd1-931a-4d87b7a8618b No revision has been approved for this page. It is currently under review by our subject matter experts. Jump to: navigation, search Loading... 1. Basic Information 2. Demand 3. Energy << Previous 1 2 3 Next >> Basic Information Utility name: City of Cartersville, Georgia (Utility Company) Effective date: 2005/10/18 End date if known: Rate name: Residential Power Service , RP3 Sector: Residential Description: Applicable to all domestic uses of a residential customer in a separately metered single family or multiply dwelling unit. Energy charge= Distribution energy charge+ Transmission Charge_ Generation Charge Subject to Power Cost Adjustment. Source or reference: Rate Binder#2 Source Parent: Comments Applicability

366

Page not found | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

21 - 12930 of 26,764 results. 21 - 12930 of 26,764 results. Download Design and Installation of a Disposal Cell Cover Field Test Paper presented at the Waste Management 2011 Conference.February 27 through March 3, 2011, Phoenix, Arizona.C.H. Benson, W.J. Waugh, W.H. Albright, G.M. Smith, R.P. Bush http://energy.gov/lm/downloads/design-and-installation-disposal-cell-cover-field-test Download Security, Emergency Planning & Safety Records http://energy.gov/cio/downloads/security-emergency-planning-safety-records Download ADMINISTRATIVE RECORDS SCHEDULE 18: SECURITY, EMERGENCY PLANNING, AND SAFETY RECORDS http://energy.gov/cio/downloads/administrative-records-schedule-18-security-emergency-planning-and-safety-records Download ADM 18 PDF http://energy.gov/cio/downloads/adm-18-pdf Download Security, Emergency Planning & Safety Records

367

Network Markup Language Base Schema version 1  

NLE Websites -- All DOE Office Websites (Extended Search)

GFD-R-P.206 GFD-R-P.206 NML-WG nml-wg@ogf.org Jeroen van der Ham, UvA (editor) Freek Dijkstra, SURFsara Roman Łapacz, PSNC Jason Zurawski, Internet2 May 2013 Network Markup Language Base Schema version 1 Status of This Document Grid Final Draft (GFD), Proposed Recommendation (R-P). Copyright Notice Copyright c Open Grid Forum (2008-2013). Some Rights Reserved. Distribution is unlim- ited. Abstract This document describes a set of normative schemas which allow the description of computer network topologies. Contents Abstract . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Contents . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 1.1 Context . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 1.2 Scope . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 1.3 Notational Conventions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5

368

R SOLICITATION, OFFER AND AWic. I 1. THIS CONTRACT IS A RATED ORDER I  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

SOLICITATION, OFFER AND AWic. I 1. THIS CONTRACT IS A RATED ORDER I RA" UNDER DPAS (15 CFR 700) > I I PAGE OF PAGES 1 I 258 2. CONTRACT NO. 1 3. SOLICITATION NO. 4. TYPE OF SOLICITATION \5. DATE ISSUED 6. REQUISITIONIPURCHASE NUMBER 13 DE-AC01-02GJ79491 DE.RP07-01GJ79491 [] SEALED BID (IFB) [X] NEGOTIATED (RFP) ''>SUED BY U.S. Department of Energy Idaho Operations Office CODE I'--_ _ _ _ _ _ ~ 8. ADDRESS OFFER TO (If other than Item 7) See Section L of RFP NOTE: Procurement Services Division, MS·1221 850 Energy Drive Idaho Falls, 10 83401·1563 In sealed bid solicitations "offer" and "offeror" mean "bid" and "bidder" SOLICITATION Electronic Proposals Only 9. Sealed offers in original and _'Refer Sec L:'_ copies for furnishing the supplies or services in the Schedule will be received at the place specified in Item 8, or if

369

Recent Publications | Advanced Photon Source  

NLE Websites -- All DOE Office Websites (Extended Search)

Entries in the APS Publications Database for the week ending 12.29.2013 Entries in the APS Publications Database for the week ending 12.29.2013 This list of entries in the APS Publications Database includes Journal Articles (9,007), Conference Proceedings (7), Books (4), and Book Chapters (76), and Dissertations (0). This list of entries in the APS Publications Database does not include abstracts, invited talks, awards, magazine articles, or patents. For the complete list, search the APS Publications Database. Inquiries about or submissions to the publications database should be directed to apspubs@aps.anl.gov. Journal Article Z. Aabdin, N. Peranio, O. Eibl, Tö W. llner, K. Nielsch, D. Bessas, R.P. Hermann, M. Winkler, Kö J. nig, Bö H. ttner, V. Pacheco, J. Schmidt, A. Hashibon, Elsä C. sser, Nanostructure, Excitations, and Thermoelectric

370

Microsoft PowerPoint - 9-04 Westsik Hanford SWFT EM Tech Exchange PNNL-SA-76075 ANL r2.pptx  

NLE Websites -- All DOE Office Websites (Extended Search)

Secondary Waste Form Secondary Waste Form Testing Joseph H. Westsik, Jr. EM Pierce, W Um, RP Pires, RJ Serne, SK Sundaram, GB Josephson Pacific Northwest National Laboratory W Gong, W Lutze, CUA/VSL, D Singh, ANL EM Waste Processing Technical Exchange November 16-18, 2010 Print Close Secondary Waste Form Testing Purpose: Conduct a testing program to support a waste form down selection and the long-term durability evaluation of a waste form(s) for the solidification of secondary wastes from the treatment and immobilization of Hanford radioactive tank wastes. Client: Washington River Protection Solutions Phase 1: Identify and assess viability of waste form candidates Phase 2: Develop, optimize, and characterize waste forms to support down selection Phase 3: Provide data on the selected waste form to

371

http://e-center.doe.gov/iips/busopor.nsf/UNID/AB7DC9D43737B75C8525731300765A51/$file/ECRSFINALRFP.pdf  

NLE Websites -- All DOE Office Websites (Extended Search)

SOLICITATION, OFFER AND AWARD SOLICITATION, OFFER AND AWARD 1. THIS CONTRACT IS A RATED ORDER UNDER DPAS (15 CFR 350) RATING N PAGE OF PAGES 1 41 3. SOLICITATION NO. 2. CONTRACT NO. DE-RP52-08NA28091 4. TYPE OF SOLICITATION SEALED BID (IFB) NEGOTIATED (RFP) 5. DATE ISSUED March 21, 2008 6. REQUISITION/PURCHASE NO. 7. ISSUED BY FAD/SSD CODE 898358 8. ADDRESS OFFER TO (If other than Item 7) DEPARTMENT OF ENERGY NNSA SERVICE CENTER PO BOX 5400 ALBUQUERQUE, NM 87185-5400 MARIA A. VIGIL 505 845-4809 MVIGIL@DOEAL.GOV SEE BLOCK 7 NOTE: In sealed bid solicitations "offer" and "offeror" mean "bid" and "bidder". SOLICITATION 9. Environmental Characterization & Remediation Services for NNSA Nevada Site Office

372

RFP  

NLE Websites -- All DOE Office Websites (Extended Search)

40 40 3. SOLICITATION NO. 2. CONTRACT NO. DE-RP52-08NA28091 4. TYPE OF SOLICITATION SEALED BID (IFB) NEGOTIATED (RFP) 5. DATE ISSUED 6. REQUISITION/PURCHASE NO. 7. ISSUED BY FAD/SSD CODE 898358 8. ADDRESS OFFER TO (If other than Item 7) DEPARTMENT OF ENERGY NNSA SERVICE CENTER PO BOX 5400 ALBUQUERQUE, NM 87185-5400 MARIA A. VIGIL 505 845-4809 MVIGIL@DOEAL.GOV SEE BLOCK 7 NOTE: In sealed bid solicitations "offer" and "offeror" mean "bid" and "bidder". SOLICITATION 9. Environmental Characterization & Remediation Services for NNSA Nevada Site Office 100% Small Business Set-Aside 10. FOR INFORMATION CALL: A. NAME See Block 7

373

September 2013 Most Viewed Documents for Fossil Fuels | OSTI, US Dept of  

Office of Scientific and Technical Information (OSTI)

Fossil Fuels Fossil Fuels EXPERIMENTAL AND THEORETICAL DETERMINATION OF HEAVY OIL VISCOSITY UNDER RESERVOIR CONDITIONS Dr. Jorge Gabitto; Maria Barrufet (2003) 42 Molecular catalytic hydrogenation of aromatic hydrocarbons and hydrotreating of coal liquids. Yang, Shiyong; Stock, L.M. (1996) 36 Fluid Dynamics in Sucker Rod Pumps Cutler, R.P.; Mansure, A.J. (1999) 35 Controlled low strength materials (CLSM), reported by ACI Committee 229 Rajendran, N. (1997) 35 Fundamental Research on Percussion Drilling: Improved rock mechanics analysis, advanced simulation technology, and full-scale laboratory investigations Michael S. Bruno (2005) 35 Autothermal Reforming of Natural Gas to Synthesis Gas Steven F. Rice; David P. Mann (2007) 34 Evaluation of Wax Deposition and Its Control During Production of

374

Enron Documents  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

1999 1999 rDEC- 15--B ]S-48 P. 02/21 December 14.1398 Vol. 5. No. SD tandard & Poors' kmRP'M ITILITIESl :- g PERS PECTVES | BH ~I UWhy Is ectric Restrturing Moving So Slowly in States? A the begi6s d 199S. Siamrd & PWfs iwpd between ne rulatory boj,. th Amore Ccaporior. ~3 b f^ rlWdiTr!- atalrtgenbardawmuldadptericemsam- Cmmwiion ACC. and Arizna's two maor OUs. 4 " -" = ' - 1·;n siit ionlt^ ddu teared clstt mrvwy. Leg AinaRt PbliSAniceCo. aod T-Tsn ,Eleaic Pori Co. .::* _.;is __ .. ?... . .ialatbla had aLdy beari dkiil dlatch be a Fuitwraolmatthifmmis n recetltionof 6 ...... - Bhrois. Cai.frf Mass h. Baftrd Fvwrre abr a new ACC crmissinc-, etfectriv Jan 4. 1999. who Otm 6 -B1im ;rwwhkluymregiJacyr n inNewac. Lamw&nmodir may try to urvlJ the senJenttfs

375

Water-Balance Cover Performance  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

2011, Phoenix, AZ 2011, Phoenix, AZ Design and Installation of a Disposal Cell Cover Field Test C.H. Benson University of Wisconsin-Madison, Madison, Wisconsin W.J. Waugh S.M. Stoller Corporation, Grand Junction, Colorado W.H. Albright Desert Research Institute, Reno, Nevada G.M. Smith Geo-Smith Engineering, Grand Junction, Colorado R.P. Bush U.S. Department of Energy, Grand Junction, Colorado ABSTRACT The U.S. Department of Energy's Office of Legacy Management (LM) initiated a cover assessment project in September 2007 to evaluate an inexpensive approach to enhancing the hydrological performance of final covers for disposal cells. The objective is to accelerate and enhance natural processes that are transforming existing conventional covers, which rely on low-

376

Notice of Availability of the Draft Site-Wide Environmental Impact Statement for Continued Operation of Los Alamos National Laboratory, Los Alamos, NM (DOE/EIS-0380D) (07/07/06)  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

638 Federal Register 638 Federal Register / Vol. 71, No. 130 / Friday, July 7, 2006 / Notices 1 Northern Natural Gas Company, 115 FERC ¶ 61,254 (2006). 1 Pinnacle West Capital Corp., 115 FERC ¶ 61,292 (2006). DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. RP06-332-000] Northern Natural Gas Company; Notice of Technical Conference June 28, 2006. The Federal Energy Regulatory Commission will convene a technical conference regarding Northern Natural Gas Company's proposal to adjust the boundary of its Operational Zones ABC and EF to the Iowa/Minnesota border in order to provide that delivery points in northern Iowa currently located in Operational Zone EF be moved to Operational Zone ABC, and delivery points in southwestern Minnesota currently located in Operational Zone

377

LLNL-ABS-499831  

National Nuclear Security Administration (NNSA)

831 831 Page 1 Session 1b: Techniques for Dynamic Experiments New Regimes for Supernova-Relevant Laboratory Astrophysics Experiments at the National Ignition Facility A.R. Miles*, H.-S. Park, B.A. Remington, W. Hsing, C.J. Keane, D.H. Kalantar, B. Maddox, B. Young, R.J. Wallace Lawrence Livermore National Laboratory F.W. Doss, R.P. Drake, M.J. Grosskopf, E.C. Harding, C.M. Huntington, C.M. Krauland, C.C. Kuranz, D.C. Marion, E. Myra University of Michigan J.D. Kilkenny, E. Giraldez, General Atomics; N. Hearn University of Chicago; T. Plewa Florida State University; J.C. Wheeler, University of Texas; W.D. Arnett, University of Arizona The National Ignition Facility (NIF) offers far more energy than has previously been available for experiments on high-energy-density (HED) laser platforms. An effort is currently underway to extend

378

CABLE AOORIs*. HICRONIZER. MOORLblOWN. NEW ,SRIEY  

Office of Legacy Management (LM)

NEW ALBANY ROAD . MOORESTOWN . NEW ]ERSEY NEW ALBANY ROAD . MOORESTOWN . NEW ]ERSEY CABLE AOORIs*. HICRONIZER. MOORLblOWN. NEW ,SRIEY be returned further obliga- may desire any patent protection, provi#ed; however, that the costa in connectSo& with the pregaration;~~fillrig nnd prosecution of the same shall be entirely: at ?SG,~~e~enS.e ,of our..company. This provision, how- ever, ls.' subJect:to eny.~prlor'arra~cmont between your Institu- tion and the government with respect to inventions and p?j,tents. ,.: 3,ri 'I :: .:v:ri :!:!p, +lo.~nl.~~! ( '.'I! &f :, > ,>,' :'It'r*i&: sltibr~!the understandfng that your Instttution will ca,rry such insurance as you'may deem ndvi~able~ln aonoec- tion with this m ill or its use ~lhile :kt the UnivsF@#b v' "t -' . ' - IN,TERNATI.ONAL PULVERIZING c0RP0RAi.1~

379

I STEPHEN M. KIM  

Office of Legacy Management (LM)

. . 44. ;: I STEPHEN M. KIM ixccutive Vice President rfifliz[i@n m$nag#gen[ cormiicn UNWfRS/TY CITY SCIENCE CENTER ,- 3508 MARKIT SlREil PHIUDELPHIA PA--l919 (2 IS) 243-2950 Cktobm 5, 1978 Mr. Fred v. shaw W .R. Grace & Co. ~sooC;m$al Division &l;imre, MD 21203 Dear Fred: Tlmnkycu verymchforwaiting this long for the enclose2 reprt. The repxtis prepared to reflect factualmtters rather thanother information. It muld be beneficial to get together in the near future todiscuss thismatter. Iamlmking forward tohearing frcmyou. Yours sincer,ely , Stephen M. Kim smlw enC. -Report+ XtdChTWk.S cc: John Hardwicke (w/o enc.) rpPyyT ,~~~?p F g+?s" ?i@J oci G 9 1378 DAVlS9:; SH3J!CAL.DIV. ENGll\iEEiliNG CEPT. .-.. .-._ _ ATTACHMENT 2 . . . . RADIATION STATUS

380

I'  

Office of Legacy Management (LM)

:!. :!. i - _ -. .: -. _. _ : _. -._ -- I' . .- Rooker Case Pile Em. Prot. Bureau N.Y.S. Department of Law New York, New York I FOIA MATERIALS FP.09 DOE Ru /a- --- L -- - -- - ~~~~~~,,.~~;' ~~i~T~~~~ ' ~-~~&~' Mt??7WZ~d$O77 ED STATES GOVERNME:: TO : 8. J. smith, Jr., Chief. Operations Branch DATE: October 21, 1952 Produc tlai Divlsio FROM : H. J. Hsnhmn. Ch da sub-Dm.cs SKEPDRT FOROCTCEJZ SIXBX.: TA::HJH:M *:scpet;r\ P.$@$ Rp3 OIlU b ~~aw*~~ WHENsEPARATa FRo~mcLOSuRES - 6ss&y%fs lwmEDoc~mAsuNcLAssIFxm T c. r,pJlS -- t/ , Ii' $m .I l Pnclosed fr the Monthly F'mgesr Report for October 1952 covering nctlvitles under the Tonawanda Sub Office for thir month. Eercl.: Report, cyr lA & 2A .._ CLASSIFICATICN C:.?!CELLED i auk%% :&K.-xJ- / 7 L

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381

Microsoft Word - SECTION_J_Appendix_C_Small_Buss_Subcont_Plan Contract.doc  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

C-1 C-1 SECTION J APPENDIX C SMALL BUSINESS, VETERAN-OWNED SMALL BUSINESS, SERVICE DISABLED VETERAN-OWNED SMALL BUSINESS, HUB-ZONE SMALL BUSINESS, SMALL DISADVANTAGED BUSINESS, AND WOMAN-OWNED SMALL BUSINESS SUBCONTRACTING PLAN Contract No.: DE-RW0000005 QA:QA J-C-2 Page Blank DE-RP28-08RW11003 July 24, 2008 Use or disclosure of data contained on this sheet is Volume I subject to the restriction on the title page of this proposal Small Business Plan-1 SECTION J APPENDIX C SMALL BUSINESS, VETERAN-OWNED SMALL BUSINESS, SERVICE DISABLED VETERAN-OWNED SMALL BUSINESS, HUB-ZONE SMALL BUSINESS, SMALL DISADVANTAGED BUSINESS, AND WOMAN-OWNED SMALL BUSINESS SUBCONTRACTING PLAN The following, together with attachments, is hereby submitted as a Subcontracting Plan to satisfy the

382

CX-001717: Categorical Exclusion Determination | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

17: Categorical Exclusion Determination 17: Categorical Exclusion Determination CX-001717: Categorical Exclusion Determination Application of 2-Dimensional Vertical Seismic Profile (VSP) Imaging to the Targeting of Exploration and Development Wells in a Basin and Range Geothermal System - Humboldt House-Rye Patch Geothermal Area - Pershing County, Nevada CX(s) Applied: B3.1, B5.12 Date: 04/19/2010 Location(s): Pershing County, Nevada Office(s): Energy Efficiency and Renewable Energy, Golden Field Office Presco Energy, LLC (Presco) would demonstrate the potential geothermal resource at the Humboldt House-Rye Patch (HH RP) area in Pershing County, Nevada. Presco would collect and interpret data from both geophone arrays and 2-dimensional surveys, deepen 2 existing geothermal wells, and followed by testing and evaluation. The Bureau of Land Management Humboldt River

383

GRIMHX verification and validation action matrix summary  

Science Conference Proceedings (OSTI)

WSRC-RP-90-026, Certification Plan for Reactor Analysis Computer Codes, describes a series of action items to be completed for certification of reactor analysis computer codes used in Technical Specifications development and for other safety and production support calculations. Validation and verification of the code is an integral part of this process. This document identifies the work performed and documentation generated to satisfy these action items for the Reactor Physics computer code GRIMHX. Each action item is discussed with the justification for its completion. Specific details of the work performed are not included in this document but are found in the references. The publication of this document signals the validation and verification effort for the GRIMHX code is completed.

Trumble, E.F.

1991-12-01T23:59:59.000Z

384

An ingress and a complete transit of HD 80606 b  

E-Print Network (OSTI)

We have used four telescopes at different longitudes to obtain near-continuous lightcurve coverage of the star HD 80606 as it was transited by its \\sim 4-MJup planet. The observations were performed during the predicted transit windows around the 25th of October 2008 and the 14th of February 2009. Our data set is unique in that it simultaneously constrains the duration of the transit and the planet's period. Our Markov-Chain Monte Carlo analysis of the light curves, combined with constraints from radial-velocity data, yields system parameters consistent with previously reported values. We find a planet-to-star radius ratio marginally smaller than previously reported, corresponding to a planet radius of Rp = 0.921 \\pm 0.036RJup .

Hidas, M G; Street, R A; Ramaprakash, A N; Mislis, D; Schmitt, J H M M; Steele, I; Barros, S C C; Pollacco, D; Ayiomamitis, A; Antoniadis, J; Nitsos, A; Seiradakis, J H; Urakawa, S

2010-01-01T23:59:59.000Z

385

Nontoxic foul-release coatings  

SciTech Connect

The Electric Power Research Institute (EPRI) under project RP-1689-9 evaluated 30 non-toxic coatings for biofouling control on steel and concrete surfaces of cooling water intakes and piping. Seven coatings were evaluated at seven sites for 2 year. The remaining 23 coatings were exposed for a variety of time lengths at the Battelle Marine Laboratory at Daytona Beach, Florida. Accelerated corrosion tests and inspection of the test panels to determine coating life were also conducted. Results of several utility conducted tests were also solicited. Silicone-based coatings performed the best with predicted lives of 2 to 4 year. Although the non-toxic coatings can be fouled by biogrowth, the rate of fouling is less and the coating can be easily cleaned. A cost-benefit methodology is presented to aid utilities to assess the potential use of non-toxic foul-release coatings at power plant cooling systems. 12 refs., 16 figs., 35 tabs.

Not Available

1989-10-01T23:59:59.000Z

386

Hydrocarbon-fuel/combustion-chamber-liner materials compatibility. Interim final report, 7 November 1986-31 October 1989  

SciTech Connect

Results of material compatibility experiments using hydrocarbon fuels in contact with copper-based combustion chamber liner materials are presented. Mil-Spec RP-1, n- dodecane, propane, and methane fuels were tested in contact with OFHC, NASA-Z, and ZrCu coppers. Two distinct test methods were employed. Static tests, in which copper coupons were exposed to fuel for long durations at constant temperature and pressure, provided compatibility data in a precisely controlled environment. Dynamic tests, using the Aerojet Carbothermal Test Facility, provided fuel and copper compatibility data under realistic booster engine service conditions. Tests were conducted using very pure grades of each fuel and fuels to which a contaminant, e.g., ethylene or methyl mercaptan, was added to define the role played by fuel impurities. Conclusions are reached as to degradation mechanisms and effects, methods for the elimination of these mechanisms, selection of copper alloy combustion chamber liners, and hydrocarbon fuel purchase specifications.

Gage, M.L.

1990-04-01T23:59:59.000Z

387

International oil and gas exploration and development: 1991  

SciTech Connect

This report starts where the previous quarterly publication ended. This first publication of a new annual series contains most of the same data as the quarterly report, plus some new material, through 1991. It also presents historical data covering a longer period of time than the previous quarterly report. Country-level data on oil reserves, oil production, active drilling rigs, seismic crews, wells drilled, oil reserve additions, and oil reserve-to-production rations (R/P ratios) are listed for about 85 countries, where available, from 1970 through 1991. World and regional summaries are given in both tabular and graphical form. The most popular table in the previous quarterly report, a listing of new discoveries, continues in this annual report as Appendix A.

Not Available

1993-12-01T23:59:59.000Z

388

Substation control and protection project  

SciTech Connect

This report describes the results of EPRI-sponsored Project RP1359-7, dealing with digital protection and control of transmission class substations. Earlier work involved a study of the feasibility of an integrated protection and control system, specification of functional requirements and selection of the optimum architecture for the system. An integrated system including line, bus and transformer protection was designed, built and laboratory tested. It was subsequently installed at the Deans substation of Public Service Electric and Gas (New Jersey). A standalone, digital transmission line system was built and installed at the Branchburg substation of PSE G, for coordinated line protection with the integrated system. The system is called WESPAC, an acronym for Westinghouse Substation Protection and Control. 52 refs., 174 figs.

Cassel, R.L.; Deliyannides, J.S.; Dzieduszko, J.W.; Harvey, J.H.; Hertz, L.H.; Klancher, F.; Mays, L.M.; McGarry, M.J.; Pettis, L.G.; Pistolese, L.F.; Reuther, J.F.; Sackin, M.; Szarmach, D.J.; Udren, E.A. (Westinghouse ABB Power T and D Co., Coral Springs, FL (USA). Relay and Telecommunications Div.)

1990-04-01T23:59:59.000Z

389

Dyonic giant magnons in CP{sup 3}: Strings and curves at finite J  

Science Conference Proceedings (OSTI)

This paper studies giant magnons in AdS{sub 4}xCP{sup 3} using both the string sigma model and the algebraic curve. We complete the dictionary of solutions by finding the dyonic generalization of the CP{sup 1} string solution, which matches the 'small' giant magnon in the algebraic curve, and by pointing out that the solution recently constructed by the dressing method is the 'big' giant magnon. We then use the curve to compute finite-J corrections to all cases, which for the nondyonic cases always match the Arutyunov-Frolov-Zamaklar result. For the dyonic RP{sup 3} magnon we recover the S{sup 5} answer, but for the small and big giant magnons we obtain new corrections.

Abbott, Michael C.; Aniceto, Ines; Sax, Olof Ohlsson [Brown University, Providence, Rhode Island 02912 (United States); Uppsala University, Box 803, SE-75108 Uppsala (Sweden)

2009-07-15T23:59:59.000Z

390

Polarization Resistance of La0.85Ca0.15MnO3 Cathodes for Solid Oxide Fuel Cells (SOFCs) Measured Using Patterned Electrodes  

SciTech Connect

Patterned cathodes of calcium-doped lanthanum manganite (LCM) were fabricated on polycrystalline yttria-stabilized zirconia (YSZ) substrates by RF magnetron sputtering and photolithographic techniques. Samples were generated with a constant electrode/electrolyte contact area but different three phase boundary (TPB) lengths (lTPB's). Electrochemical impedance spectroscopy (EIS) was performed in the oxygen partial pressure (pO2) and temperature range of 10-3 atm to 1.00 atm and 600-800 C respectively. The area specific polarization resistance, Rp, was found to scale linearly with the inverse of lTPB, suggesting that the TPB is the active region for oxygen reduction. The resistivity decreased with increased temperature and pO2 and showed an activation energy of 1.17 +/- 0.03 eV.

Miara, Lincoln J.; Yoon, Kyung J.; Topping, Stephen; Saraf, Laxmikant V.; Pal, Uday B.; Gopalan, Srikanth

2010-04-25T23:59:59.000Z

391

Suppression of the stellar enhancement factor and the reaction {sup 85}Rb(p,n){sup 85}Sr  

SciTech Connect

It is shown that a Coulomb suppression of the stellar enhancement factor occurs in many endothermic reactions at and far from stability. Contrary to common assumptions, reaction measurements for astrophysics with minimal impact of stellar enhancement should be preferably performed for those reactions instead of their reverses, despite of their negative Q value. As a demonstration, the cross section of the astrophysically relevant {sup 85}Rb(p,n){sup 85}Sr reaction has been measured by activation between 2.16{<=}E{sub c.m.}{<=}3.96 MeV and the astrophysical reaction rates at p process temperatures for (p,n) as well as (n,p) are directly inferred from the data. Additionally, our results confirm a previously derived modification of a global optical proton potential. The presented arguments are also relevant for other {alpha}- and proton-induced reactions in the p, rp, and {nu}p processes.

Rauscher, T. [Department of Physics, University of Basel, CH-4056 Basel (Switzerland); Kiss, G. G.; Gyuerky, Gy.; Simon, A.; Fueloep, Zs.; Somorjai, E. [Institute of Nuclear Research (ATOMKI), H-4001 Debrecen, P. O. Box 51 (Hungary)

2009-09-15T23:59:59.000Z

392

Design and development of the CSNS ion source control system  

E-Print Network (OSTI)

After the CSNS ion source test stand has been stably working for years, an online control system for CSNS ion source aiming to be more stable and reliable is now under development. F3RP61-2L, a new PLC CPU module under Linux system, is introduced to the system as an IOC, to function together with the I/O modules of FA-M3 PLC on the PLC-bus. The adoption of the new IOC not only simplifies the architecture of the control system, but also improves the data transmission speed. In this paper, the design and development of the supervisory and control system for CSNS ion source are described.

Lu Yan-Hua; Li Gang; Ouyang Hua-Fu

2013-04-10T23:59:59.000Z

393

The CDF-II tau physics program triggers, tau ID and preliminary results  

SciTech Connect

The study of processes containing {tau} leptons in the final state will play an important role at Tevatron Run II. Such final states will be relevant both for electroweak studies and measurements as well as in searches for physics beyond the Standard Model. The present paper discusses the physics opportunities and challenges related to the implementation of new set of triggers able to select events containing tau candidates in the final state. They illustrate, in particular, the physics capabilities for a variety of new physics scenarios such as supersymmetry (SUSY), SUSY with Rp-parity violation, with Bilinear parity violation or models with the violation of lepton flavor. Finally, they present the first Run II results obtained using some of the described tau triggers.

C. Pagliarone et al.

2003-11-03T23:59:59.000Z

394

Plant layup and equipment preservation sourcebook: Interim report  

Science Conference Proceedings (OSTI)

US nuclear generating plant systems and equipment have received very sophisticated chemistry and environmental controls during operation, but very little during construction and outages. As plant construction times became longer, and operating plants experienced outages of significant length, the component damage and system contamination occurring during this idle time has become greater, to the extent that plant startup schedules or the ability to keep the plant operational are sometimes affected. This has led to limited efforts in the industry to control component internal chemistry and environment by planned lay-up procedures. These efforts have been thwarted by a lack of information on how to do equipment lay-ups, and a lack of data base to quantify the value of various lay-up techniques. EPRI authorized the preparation of this sourcebook as part of a research program, RP2815-1, with the goal of providing a convenient and unified source of plant lay-up information.

Mentink, H.W.; Hagan, K.A.; Lovett, C.G.

1987-03-01T23:59:59.000Z

395

Offer of Settlement and Stipulation and Agreement Dear Ms. Rogers:  

E-Print Network (OSTI)

all issues raised in the captioned proceeding. In addition, Chandeleur filed a tariff sheet containing the settlement rates to be effective April 1, 2004. 1 As discussed below, the Commission finds that the proposed settlement is fair, reasonable and in the public interest with the terms and conditions to be effective April 1, 2004, as provided for in the Settlement. Background 2. On September 30, 2003, Chandeleur filed a tariff sheet reflecting an NGA section 4 rate increase in the captioned docket. Chandeleurs proposed rates were based on an overall cost of service of $5,972,623, which represented an increase of 116 percent over current rates. Chandeleur proposed an overall rate of return of 10.5 percent with a return on equity of 12.85 percent and a cost of debt of 6.98 percent based upon a 1 Chandeleur submitted 2 nd Revised Fourteenth Rev. Sheet No. 5, to its FERC Gas Tariff, Second Revised Volume No. 1, in conjunction with its Settlement proposal. The Commission notes that Chandeleur also submitted this tariff sheet in its Motion Rate Filing of March 31, 2004, in Docket No. RP03-625-001. The Commission will act on this tariff sheet in that docket. Docket No. RP03-625-000- 2-hypothetical capital structure of 40 percent debt and 60 percent equity. Chandeleur also proposed a change in its depreciation rates from 1.1 percent to 2.1 percent and a change in its negative salvage rate from 0.15 percent to 0.67 percent. Chandeleur requested that its rates be made effective November 1, 2003. 3. On October 31, 2003, the Commission accepted and suspended Chandeleurs tariff sheet to be effective April 1, 2004, subject to refund. 2

Janice E. Rogers

2004-01-01T23:59:59.000Z

396

Isolation and characterization of Solenopsis invicta virus 3, a new positive-strand RNA virus infecting the red imported fire ant, Solenopsis invicta  

Science Conference Proceedings (OSTI)

We report the discovery of a new virus from the red imported fire ant, Solenopsis invicta. Solenopsis invicta virus 3 (SINV-3) represents the third virus discovered from this ant species using the metagenomics approach. The single (positive)-strand RNA, monopartite, bicistronic genome of SINV-3 was sequenced in entirety (GenBank accession number (FJ528584)), comprised of 10,386 nucleotides, and polyadenylated at the 3' terminus. This genome size was confirmed by Northern analysis. The genome revealed 2 large open reading frames (ORFs) in the sense orientation with an untranslated region (UTR) at each end and between the two ORFs. The 5' proximal ORF (ORF 1) encoded a predicted protein of 299.1 kDa (2580 amino acids). The 3' proximal ORF (ORF 2) encoded a predicted protein of 73.2 kDa (651 amino acids). RNA-dependent RNA polymerase (RdRp), helicase, and protease domains were recognized in ORF 1. SDS-PAGE separation of purified SINV-3 particles yielded 2 bands (ostensibly capsid proteins) with a combined molecular mass of 77.3 kDa which was similar to the mass predicted by ORF 2 (73.2 kDa). Phylogenetic analysis of the conserved amino acid sequences containing domains I to VIII of the RdRp from dicistroviruses, iflaviruses, plant small RNA viruses, picornaviruses, and 4 unassigned positive-strand RNA viruses revealed a trichotomous phenogram with SINV-3 and Kelp fly virus comprising a unique cluster. Electron microscopic examination of negatively stained samples of SINV-3 revealed isometric particles with apparent projections and a diameter of 27.3 +- 1.3 nm. SINV-3 was successfully transmitted to uninfected workers by feeding. The minus (replicative) strand of SINV-3 was detected in worker ants indicating replication of the virus. The possibility of using SINV-3 as a microbial control agent for fire ants is discussed.

Valles, Steven M., E-mail: Steven.Valles@ars.usda.go [Center for Medical, Agricultural and Veterinary Entomology, USDA-ARS, 1600 SW 23rd Drive, Gainesville, FL 32608 (United States); Hashimoto, Yoshifumi [Boyce Thompson Institute for Plant Research at Cornell University, Tower Road, Ithaca, NY 14853 (United States)

2009-06-05T23:59:59.000Z

397

Dynamic reduction, Version 1. 0  

SciTech Connect

This report describes the theoretical background of the EPRI Dynamic Reduction DYNRED V 1.0. EPRI initiated research under project RP763 to develop the original reduction program DYNEQU. This program was the first to be based on the concept of aggregating of coherent groups of synchronous generators into a single equivalent generator model. While technically advanced, DYNEQU proved difficult to use. Since then, the stability problems encountered in power system planning and operations have changed. The emphasis on first swing transient stability has been replaced by emphasis on inter-area oscillations and voltage stability. The method of identification of coherent generators used in DYNEQU is based on the comparison of rotor angle swings, in a linearized system model, following a fault. It has been shown that this method of coherency identification is good for first swing stability. For inter-area oscillation studies, this method of generator aggregation is less accurate. Far better, are identification methods based on the structure of the power system. Because of these changes in the requirements for reduced order power system models, a new dynamic reduction program (DYNRED) has been developed under EPRI project RP2447-1. It is coherency based, as is DYNEQU, but it has structurally based coherency identification methods in addition to the method used in DYNEQU. This report describes the techniques used in DYNRED, that is: Coherency Identification; Network Reduction; Method of Aggregation, Generator Aggregation, Excitation Aggregation, Primemover/Governor Aggregation. An example of the application of DYNRED to the reduction of a large interconnected power system model is also presented. DYNRED uses the special modeling and network solution techniques developed to enable systems having up to 12,000 bus to be studied. Dynamic data is completely compatible between MASS, PEALS, and the EPRI Extended Transient Midterm Stability Program (ETMSP).

Rogers, G.J.; Wong, D.Y.; Ottevangers, J.; Wang, L. (Ontario Hydro, Toronto, ON (Canada))

1993-04-01T23:59:59.000Z

398

Natural Product Biosynthesis: Friend or Foe? From Anti-tumor Agent to Disease Causation  

E-Print Network (OSTI)

Biosynthetic natural products are invaluable resources that have been gleaned from the environment for generations, and they play an essential role in drug development. Natural product biosynthesis also possesses the latent ability to affect biological systems adversely. This work implements recent advances in genomic, proteomic and microbiological technologies to understand further biosynthetic molecules that may influence progression of human disease. Azinomycin A and B are antitumor metabolites isolated from the terrestrial bacterium Streptomyces sahachiroi. The azinomycins possess an unusual aziridine [1,2-a] pyrrolidine ring that reacts in concert with an epoxide moiety to produce DNA interstrand cross-links. Genomic sequencing of S. sahachiroi revealed a putative azinomycin resistance protein (AziR). Overexpression of AziR in heterologous hosts demonstrated the protein increases cell viability and decreases DNA damage response in the presence of azinomycin. Fluorescence titration indicated AziR functions as an azinomycin binding protein. An understanding of azinomycin resistance is important for future engineering and drug delivery strategies. Additionally, the S. sahachiroi draft genome obtained via 454 pyrosequencing and Illumina sequencing revealed several silent secondary metabolic pathways that may provide new natural products with biomedical application. ?-lactoglobulin (BLG), the most abundant whey protein in bovine milk, has been observed to promote the self-condensation of retinal and similar ?,?-unsaturated aldehydes. BLG is a possible non-genetic instigator of cycloretinal and A2E accumulation in the macula, a condition associated with age-related macular degeneration. BLG-mediated terpenal condensation has been optimized for in vitro study with the retinal mimic citral. In rabbits fed retinal and BLG or skim milk, cycloretinal formation was detected in the blood by 1H-NMR, and SDS-PAGE analysis indicated BLG was present in blood serum, suggesting the protein survives ingestion and retains catalytic activity. Mass spectrometry and site-directed mutagenesis provided mechanistic insight toward this unusual moonlighting behavior. The experiments described in this dissertation serve to further natural product biosynthesis discovery and elucidation as they relate to consequences for human health. Efforts to solve azinomycin biosynthesis via enzymatic reconstitution, characterize compounds produced by orphan gene clusters within S. sahachiroi, and obtain a clear mechanism for BLG-promoted cycloterpenal formation are immediate goals within the respective projects.

Foulke-Abel, Jennifer

2010-12-01T23:59:59.000Z

399

Artificial Retina In the News  

NLE Websites -- All DOE Office Websites (Extended Search)

Press Releases Press Releases News Articles Press Releases Mark Humayun Inducted into Institute of Medicine Institute of Medicine press release, 10/12/2009 Artificial Retina Project Wins Prestigious 2009 R&D 100 Award Article and multiple press releases, 07/20/2009 Second Sight to Double Patient Enrollment for Argus(tm) II Retinal Implant U.S. Clinical Trial Second Sight press release, 05/04/09 See more releases in Press Release Archive Recent Articles Bionic eye opens new world of sight for blind National Public Radio, October 20, 2009 Burst of technology helps blind to see New York Times, September 26, 2009 Artificial retina project has ORNL roots ORNL Reporter, August 28, 2009 The "holy grail" of ophthalmic devices Assembly Magazine, August 20, 2009 Artificial-retina project designed to restore sight to the blind

400

Micromachined electrode array  

DOE Patents (OSTI)

An electrode array is disclosed which has applications for neural stimulation and sensing. The electrode array, in certain embodiments, can include a plurality of electrodes each of which is flexibly attached to a common substrate using a plurality of springs to allow the electrodes to move independently. In other embodiments of the electrode array, the electrodes can be fixed to the substrate. The electrode array can be formed from a combination of bulk and surface micromachining, and can include electrode tips having an electroplated metal (e.g. platinum, iridium, gold or titanium) or a metal oxide (e.g. iridium oxide) for biocompatibility. The electrode array can be used to form a part of a neural prosthesis, and is particularly well adapted for use in an implantable retinal prosthesis.

Okandan, Murat (Edgewood, NM); Wessendorf, Kurt O. (Albuquerque, NM)

2007-12-11T23:59:59.000Z

Note: This page contains sample records for the topic "retinitis pigmentosa rp" from the National Library of EnergyBeta (NLEBeta).
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to obtain the most current and comprehensive results.


401

One patient's artificial retina story  

NLE Websites -- All DOE Office Websites (Extended Search)

Helping To Advance the Frontiers of Medical Research Helping To Advance the Frontiers of Medical Research A patient's perspective on what the retinal implant has meant to her Patient following a white line In psychophysical testing, Kathy B. demonstrates how her artificial retina implant allows her to walk along a white line to its termination. A highly functioning person with a job, family, and household to tend to, Kathy B. doesn't feel like she's blind despite the fact that she's had no vision for about 15 years. Nevertheless, she was excited when she recently was able to find the full moon in the dark, nighttime sky. "We were out walking, and I looked upwards, scanning my head back and forth," Kathy B. explains. "All of a sudden, I saw a big flash, and I asked my husband, 'Is that the moon?'" It was, and she began thinking

402

Artificial retina: Invention of the year  

NLE Websites -- All DOE Office Websites (Extended Search)

1513_retina 1513_retina 11/15/2013 The Argus II artificial retina, in which Lawrence Livermore has played a prominent roll, has enough resolution for people to see the lines of a crosswalk, find objects and read letters a couple of centimeters tall. Image by Dan Foley/Second Sight Argus II. Artificial retina: Invention of the year Anne M Stark, LLNL, (925) 422-9799, stark8@llnl.gov The artificial retina, in which Lawrence Livermore has played a prominent role, has earned a place in the top 25 best inventions of the year 2013 from Time Magazine. The invention also has garnered a 2013 best innovation designation by Popular Science. This Department of Energy funded project resulted in the creation of the first-ever retinal prosthesis -- or bionic eye -- approved in the United

403

Livermore, Los Alamos Team for Artificial Retina Project to Help Restore Vision for Many  

NLE Websites -- All DOE Office Websites (Extended Search)

9 9 6 www.federallabs.org Livermore, Los Alamos Team for Artificial Retina Project to Help Restore Vision for Many signals in the eye that the brain uses to create a visual image. As a core member of the team, Los Alamos National Laboratory is developing and applying techniques for the functional imaging of physiological and prosthetic stimulation in neural tissue to characterize information encoding and processing by the retina and to validate the efficacy of electrical stimulation. Coupled experimental studies and computer simulations are being used to investigate the biophysical and physiological properties of retinal neuronal tissue. In clinical trials, patients with vision loss were able to successfully identify objects, increase mobility, and

404

The DOE Artificial Retina Project  

NLE Websites -- All DOE Office Websites (Extended Search)

ENvisioNiNG siGht for thE BLiND ENvisioNiNG siGht for thE BLiND The DOE Artificial Retina Project Leveraging DOE expertise to enhance the quality of life for millions Major advances achieved by researchers in the U.S. Department of Energy's (DOE) Artificial Retina Project are beginning to offer some hope to millions of people blinded by retinal diseases worldwide. In a breakthrough operation performed by project leaders at the Doheny Eye Institute (University of Southern California) in 2002, doctors threaded an electrode-studded array through an incision into the eye of a man who had been blind for 50 years and tacked it onto his damaged retina. Within weeks, the 77-year-old patient could see patterns of light and dark that allowed him to detect motion and locate and differentiate

405

Artificial Retina Project Collaborators  

NLE Websites -- All DOE Office Websites (Extended Search)

Collaborators map Map of project collaborators and descriptions of their primary contributions. Click on map for larger image. Artificial Retina Project Collaborators An effort spanning 6 DOE national laboratories, 4 universities, and private industry Multidisciplinary groups across the United States are using a highly focused and coordinated approach to develop a dramatically improved retinal prosthetic device to restore sight to the blind. The Doheny Eye Institute, Oak Ridge National Laboratory, and Second Sight(tm) Medical Products, Inc., lead the collaborative effort through an executive committee. Meet the Team Doheny logo Doheny Eye Institute at the University of Southern California Provided medical direction and performs preclinical and clinical testing of the electrode array implants. Leads the Artificial Retina Project.

406

Experiment Hazard Class 10.2 - UV Light  

NLE Websites -- All DOE Office Websites (Extended Search)

2 - Ultraviolet Light 2 - Ultraviolet Light Applicability This hazard classification applies to all experiments involving the use of ultraviolet radiation generating equipment.Ultraviolet light (UV) is non-ionizing radiation in the 180 to 400-nanometer wavelength region of the electromagnetic spectrum. Ultraviolet light poses hazards: Eyes hazards - inflammation, cataracts, retinal damage Skin hazards - sunburn, accelerate wrinkling, increased risk of skin cancer Invisible Possible ozone generation Experiment Category Experiments involving only experiment hazard class 10.2 qualify for medium risk. The addition of other hazard classes may require the experiment to be categorized as high risk and undergo additional reviews. Experiment Hazard Control Verification Statements Engineered Controls - Shield or contain UV as close to the source as

407

Statistical Characterization and Segmentation of Drusen in Fundus Images  

SciTech Connect

Age related Macular Degeneration (AMD) is a disease of the retina associated with aging. AMD progression in patients is characterized by drusen, pigmentation changes, and geographic atrophy, which can be seen using fundus imagery. The level of AMD is characterized by standard scaling methods, which can be somewhat subjective in practice. In this work we propose a statistical image processing approach to segment drusen with the ultimate goal of characterizing the AMD progression in a data set of longitudinal images. The method characterizes retinal structures with a statistical model of the colors in the retina image. When comparing the segmentation results of the method between longitudinal images with known AMD progression and those without, the method detects progression in our longitudinal data set with an area under the receiver operating characteristics curve of 0.99.

Santos-Villalobos, Hector J [ORNL; Karnowski, Thomas Paul [ORNL; Aykac, Deniz [ORNL; Giancardo, Luca [ORNL; Li, Yaquin [University of Tennessee, Knoxville (UTK); Nichols, Trent L [ORNL; Tobin Jr, Kenneth William [ORNL; Chaum, Edward [University of Tennessee, Knoxville (UTK)

2011-01-01T23:59:59.000Z

408

IRRADIANCE THRESHOLDS FOR CHORIORETINAL LESIONS  

SciTech Connect

With use of a high-intensity light source to produce chorioretinal lesions in the eyes of rabbits, cats, and guinea pigs, we determined, at different levels of retinal irradiance, the exposure time which produced an ophthalmoscopically visible lesion it was found that at irradiance levels greater than 2 cal. per square centimeter per second a radiant exposure of 1.0 cal. per square centimeter produced a threshold lesion. At irradiance levels 1ess than 0.7 cal. per square centimeter per second lesions could not be produced at any exposure time through 10 seconds. Histological data on the nature of the lesions and course of healing are presented and discussed. (auth)

DeMott, D.W.; Davis, T.P.

1959-10-01T23:59:59.000Z

409

Metabolically Efficient Codes in The Retina  

E-Print Network (OSTI)

We tested the hypothesis that the neural code of retinal ganglion cells is optimized to transmit visual information at minimal metabolic cost. Under a broad ensemble of light patterns, ganglion cell spike trains consisted of sparse, precise bursts of spikes. These bursts were viewed as independent neural symbols. The noise in each burst was measured via repeated presentation of the visual stimulus, and the energy cost was estimated from the total charge flow in a biophysically realistic model of ganglion cell spiking. Given these costs and noise, the theory of efficient codes predicts an optimal distribution of symbol usage. Symbols that are either noisy or metabolically costly are suppressed in this optimal code. We found excellent qualitative and quantitative agreement with the measured distribution of burst sizes for ganglion cells in the tiger salamander retina.

Vijay Balasubramanian; Michael J Berry

2001-05-06T23:59:59.000Z

410

Normalized Compression Distance of Multiples  

E-Print Network (OSTI)

Normalized compression distance (NCD) is a parameter-free similarity measure based on compression. The NCD between pairs of objects is not sufficient for all applications. We propose an NCD of finite multisets (multiples) of objacts that is metric and is better for many applications. Previously, attempts to obtain such an NCD failed. We use the theoretical notion of Kolmogorov complexity that for practical purposes is approximated from above by the length of the compressed version of the file involved, using a real-world compression program. We applied the new NCD for multiples to retinal progenitor cell questions that were earlier treated with the pairwise NCD. Here we get significantly better results. We also applied the NCD for multiples to synthetic time sequence data. The preliminary results are as good as nearest neighbor Euclidean classifier.

Cohen, Andrew R

2012-01-01T23:59:59.000Z

411

Directed evolution of phosphotriesterase: towards the efficient detoxification of sarin and soman  

E-Print Network (OSTI)

Directed evolution studies were done with PTE for the enhancement of hydrolysis of both sarin and soman analogs. Particular attention was focused on the toxic SpRc and SpSc isomers of the soman analog, and the Sp isomer of the sarin analog. Double substitution libraries yielded several mutants that had enhanced activity for the substrates. Among them was the double mutant, H257Y-L303T, which displayed a 462-fold increase in activity for hydrolysis of the most toxic SpSc isomer of the GD analog in comparison to the wild type. Several other mutants such as the triple mutants H254R-H257A-L303T and H254R-H257S-L303T had enhancements of between 150- and 200-fold, and had also displayed a different order of stereoselectivity relative to the wild type. For these mutants, the order of preferential hydrolysis was such that the SpRc isomer was preferentially hydrolyzed first. In contrast, the order of preferential hydrolysis for the wild type was that the RpRc was hydrolyzed first, followed by the RpSc, SpRc, and then the SpSc isomer. The reversal of stereoselective preference was also seen with the double substitution library members for hydrolysis of the sarin analog isomers. However, there were no significant improvements for sarin analog hydrolysis in these libraries. Among the best mutants obtained were H254G-H257W, H254G-H257R, and H257Y, all of which had catalytic efficiencies on the order of 106 M-1 s-1 for hydrolysis of the Sp isomer. The toxicity for analogs of sarin, soman, and VX was evaluated using Hydra attenuata as a model organism. The toxicity of each compound was assessed quantitatively by measuring the minimal effective concentration within 92 h in H. attenuata. There was a positive correlation between the molecular hydrophobicity of the compound and its ability to cause toxicity. Results from this study indicate the potential for application of this assay in the field of organophosphate nerve agent detection, as well as for the prediction of toxicity of structurally similar organophosphate compounds. The minimal effective concentration for two of the VX analogs was 2 orders of magnitude more toxic than the analog for soman and four orders of magnitude more toxic than the analog for sarin.

Lum, Karin Tien

2003-05-01T23:59:59.000Z

412

The ESO Slice Project (ESP) Galaxy Redshift Survey. VII. The Redshift and Real-Space Correlation Functions  

E-Print Network (OSTI)

We present analyses of the two-point correlation properties of the ESP galaxy redshift survey. From the redshift-space correlation function xi(s), we see positive clustering out to separations ~50/h Mpc, with a smooth break on larger scales and zero-crossing between 60 and 80/h Mpc. xi(s) is reasonably well described by a shallow power law with \\gamma~1.5 between 3 and 50/h Mpc, while on smaller scales (0.2-2/h Mpc) it has a shallower slope (\\gamma~ 1). We examine the full effect of redshift-space distortions through the two-dimensional correlation function xi(rp,pi), from which we project out the real-space xi(r) below 10/h Mpc. This function is well described by a power-law model (r/r_o)^{-\\gamma}, with r_o=4.15^{+0.20}_{-0.21} h^{-1} Mpc and \\gamma=1.67^{+0.07}_{-0.09}. Comparison to other redshift surveys shows a consistent picture in which clustering remains positive out to separations of 50/h Mpc or larger, in substantial agreement with the results obtained from angular surveys like the APM and EDSGC. Also the shape of the two-point correlation function is remarkably unanimous among these data sets, in all cases requiring more power above 5/h Mpc (a `shoulder'), than a simple extrapolation of the canonical xi(r)=(r/5)^{-1.8}. xi(s) for volume-limited subsamples shows evidence of luminosity segregation only for the most luminous sample with M_{b_J}\\le -20.5. When redshift-space distortions are removed through projection of xi(rp,pi), however, a weak dependence on luminosity is seen at small separations also at fainter magnitudes. This effect is masked in redshift space, as the mean pairwise velocity dispersion experiences a parallel increase, basically erasing the effect of the clustering growth on xi(s).

L. Guzzo; J. G. Bartlett; A. Cappi; S. Maurogordato; E. Zucca; G. Zamorani; C. Balkowski; A. Blanchard; V. Cayatte; G. Chincarini; C. A. Collins; D. Maccagni; H. MacGillivray; R. Merighi; M. Mignoli; D. Proust; M. Ramella; R. Scaramella; G. M. Stirpe; G. Vettolani

1999-01-27T23:59:59.000Z

413

PNWD  

Office of Legacy Management (LM)

- - - - - -- - - - -- -- -- - - - - - - - - - - -- - - - - - - -- - - -- - --, PNWD -3802 Battelle 71u! Business a/Innovation Monticello Mill Ta:i.lings Site Macroinvertebrate Sampling for 2006 A.L. Bunn R.P. Mueller CA. Duberstein J.M. Brandenberger February 2007 Prepared for the U.S. Department of Ene rgy under Con tract DE-AC13-02GJ79491 DI SCLAIM ER This report was prepared as an account of wo rk spo nso red by an agency of th e United States Go vernment. N either th e United States G overnment n or any agency thereof, nor Battelle Mem orial In stitute, no r an y o f th eir em ployees, m akes any w arranty, ex press o r implied, o r as s u mes any leg al liabili ty o r resp o nsib ility for the acc u ra cy, comple te ness, o r u sefuln ess of an y info rmation, ap paratus, p roduct , or proce ss d is close d, or re p re sents th at its u se would no t infri nge p rivately owned rights. Reference he rein to any specific commercial product, process,

414

An approximation trichotomy for Boolean #CSP  

E-Print Network (OSTI)

We give a trichotomy theorem for the complexity of approximately counting the number of satisfying assignments of a Boolean CSP instance. Such problems are parameterised by a constraint language specifying the relations that may be used in constraints. If every relation in the constraint language is affine then the number of satisfying assignments can be exactly counted in polynomial time. Otherwise, if every relation in the constraint language is in the co-clone IM2 from Posts lattice, then the problem of counting satisfying assignments is complete with respect to approximation-preserving reductions in the complexity class #RH?1. This means that the problem of approximately counting satisfying assignments of such a CSP instance is equivalent in complexity to several other known counting problems, including the problem of approximately counting the number of independent sets in a bipartite graph. For every other fixed constraint language, the problem is complete for #P with respect to approximation-preserving reductions, meaning that there is no fully polynomial randomised approximation scheme for counting satisfying assignments unless NP=RP. 1

Martin Dyer; Leslie Ann Goldberg; Mark Jerrum

2007-01-01T23:59:59.000Z

415

Compilation of Diversity Factors and Schedules for Energy and Cooling Load Calculations, Phase II Report - Identified Relevant Data Sets, Methods, and Variability Analysis  

E-Print Network (OSTI)

This is the second report of the ASHRAE 1093-RP project that reports on the progress during the scheduled Phase II effort. In this report, we present: (1) the data sets identified and acquired required for the analysis; (2) the method adopted for classifying the Office building categories; (3) the relevant methods for daytyping necessary for creating the typical load shapes for energy and cooling load calculation; (4) the relevant robust variability (uncertainty) analysis; (5) typical load shapes reported in the literature; (6) a test to assure the non-weather dependency (seasonal variation) of the lighting and equipment data sets; and (7) a proposed occupancy surrogate variable. The results obtained during Phase II will enable us to proceed with Phase III, as planned. Phase III will cover: (1) developing the typical load shapes for the acquired data sets, using the proposed method, for both energy and cooling load calculations; (2) developing the tool-kit for deriving the new diversity factors and general guidelines for their use; and (3) developing illustrative examples of the use of the diversity factors in the DOE-2 and BLAST simulation programs.

Abushakra, B.; Haberl, J. S.; Claridge, D. E.

1999-01-01T23:59:59.000Z

416

An integrated top-down and bottom-up strategy for characterization protein isoforms and modifications  

SciTech Connect

Bottom-up and top-down strategies are two commonly used methods for mass spectrometry (MS) based protein identification; each method has its own advantages and disadvantages. In this chapter, we describe an integrated top-down and bottom-up approach facilitated by concurrent liquid chromatography-mass spectrometry (LC-MS) analysis and fraction collection for comprehensive high-throughput intact protein profiling. The approach employs a high resolution reversed phase (RP) LC separation coupled with LC eluent fraction collection and concurrent on-line MS with a high field (12 Tesla) Fourier-transform ion cyclotron resonance (FTICR) mass spectrometer. Protein elusion profiles and tentative modified protein identification are made using detected intact protein mass in conjunction with bottom-up protein identifications from the enzymatic digestion and analysis of corresponding LC fractions. Specific proteins of biological interest are incorporated into a target ion list for subsequent off-line gas-phase fragmentation that uses an aliquot of the original collected LC fraction, an aliquot of which was also used for bottom-up analysis.

Wu, Si; Tolic, Nikola; Tian, Zhixin; Robinson, Errol W.; Pasa-Tolic, Ljiljana

2011-04-15T23:59:59.000Z

417

Topology of Dupin hypersurfaces with six distinct principal curvatures  

E-Print Network (OSTI)

Let M be a Dupin hypersurface in the unit sphere S n+1 with six distinct principal curvatures. The main purpose of the present paper is to show M is either diffeomorphic to SU(2) \\Theta SU(2)=Q 8 or homeomorphic to the tube around an embedded 5dimensional complex Fermat hypersurface X 5 (2) in S 13 , where Q 8 ae SU(2) = Sp(1) denotes the subgroup f\\Sigma1; \\Sigmai; \\Sigmaj; \\Sigmakg and X 5 (2) = f[z 0 ; z 1 ; \\Delta \\Delta \\Delta z 6 ] 2 CP 6 jz 2 0 +z 2 1 + \\Delta \\Delta \\Delta + z 2 6 = 0g. Moreover, in the former case, all of the focal manifolds are diffeomorphic to S 3 \\Theta RP 2 ; In the latter case, one of the focal manifolds is homeomorphic to X 5 (2). 1 Introduction A closed n-dimensional submanifold in the unit sphere S n+1 is called a Dupin hypersurface if the multiplicities of the principal curvatures are constant and if each principal curvature function restricted to the leaves of the distribution T = fxjAx = xg is constant [16]. The most important sp...

Fuquan Fang

1995-01-01T23:59:59.000Z

418

Checkerboards, stripes and corner energies in spin models with competing interactions  

E-Print Network (OSTI)

We study the zero temperature phase diagram of Ising spin systems in two dimensions in the presence of competing interactions, long range antiferromagnetic and nearest neighbor ferromagnetic of strength J. We first introduce the notion of a "corner energy" which shows, when the antiferromagnetic interaction decays faster than the fourth power of the distance, that a striped state is favored with respect to a checkerboard state when J is close to J_c, the transition to the ferromagnetic state, i.e., when the length scales of the uniformly magnetized domains become large. Next, we perform detailed analytic computations on the energies of the striped and checkerboard states in the cases of antiferromagnetic interactions with exponential decay and with power law decay r^{-p}, p>2, that depend on the Manhattan distance instead of the Euclidean distance. We prove that the striped phase is always favored compared to the checkerboard phase when the scale of the ground state structure is very large. This happens for J\\lesssim J_c if p>3, and for J sufficiently large if 2

Alessandro Giuliani; Joel L. Lebowitz; Elliott H. Lieb

2011-06-05T23:59:59.000Z

419

Hands-On Session 6: Monolayer Boron Nitride BerkeleyGW Workshop  

NLE Websites -- All DOE Office Websites (Extended Search)

Hands-On Session 6: Monolayer Boron Nitride Hands-On Session 6: Monolayer Boron Nitride BerkeleyGW Workshop 11/23/2013 Diana Qiu Goals: 1. Demonstrate a GW-BSE calculation for a 2D semiconductor 2. Look at the behavior of ε -1 00 (q) for a system with a truncated Coulomb interaction 3. Learn how to use BerkeleyGW's visualization tools to look at the exciton wave function Instructions: Please copy the example directory into your scratch directory >> cp -rP /project/projectdirs/m1694/BGW-2013/6-boron_nitride $SCRATCH/ 1-MF ● Please go the directory ``6-boron_nitride/1-mf/`` ● Enter each directory in numerical order and follow the instructions in the README files. Some things to note for 2D calculations: ● The system is in a periodic supercell. Though we will not do so in this calculation, you should always converge the k-grid sampling and amount of vacuum between

420

SR0113?  

NLE Websites -- All DOE Office Websites (Extended Search)

December 5, 2001 December 5, 2001 Media Contact: Bill Taylor (803) 725-2889 DOE Announces Availability Of Final RFP For SRS Salt Processing Facility Flag Ribbon Art Aiken, SC -- Today the Department of Energy (DOE) made available the Final Request for Proposals (RFP) for the acquisition of services to design, construct, and commission a facility to process the salt portion of high-level radioactive waste currently stored in underground tanks at the Savannah River Site (SRS). The Salt Waste Processing Facility Final RFP (DE-RP09-02SR22210) is available at the DOE Public Reading Room at the Gregg-Graniteville Library at the University of South Carolina-Aiken in Aiken, South Carolina, or via the Internet at http://e-center.doe.gov. The Final RFP identifies Caustic Side Solvent Extraction as the preferred technology for the cesium separation process, consistent with the Savannah River Site Salt Processing Alternatives Final Supplemental Environmental Impact Statement and the subsequent Record of Decision issued in October 2001.

Note: This page contains sample records for the topic "retinitis pigmentosa rp" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


421

A High Pressure Carbon Dioxide Separation Process for IGCC Plants  

NLE Websites -- All DOE Office Websites (Extended Search)

High Pressure Carbon Dioxide Separation Process for IGCC Plants High Pressure Carbon Dioxide Separation Process for IGCC Plants 1 A High Pressure Carbon Dioxide Separation Process for IGCC Plants S.S. Tam 1 , M.E. Stanton 1 , S. Ghose 1 , G. Deppe 1 , D.F. Spencer 2 , R.P. Currier 3 , J.S. Young 3 , G.K. Anderson 3 , L.A. Le 3 , and D.J. Devlin 3 1 Nexant, Inc. (A Bechtel Technology & Consulting Company) 45 Fremont St., 7 th Fl., San Francisco, CA 94506 2 SIMTECHE 13474 Tierra Heights Road, Redding, CA 96003 3 Los Alamos National Laboratory P.O. Box 1663 (MS J567), Los Alamos, NM 87545 1.0 INTRODUCTION Under separate contracts from the U.S. Department of Energy, Office of Fossil Energy (DOE- FE), Los Alamos National Laboratory, and a team of SIMTECHE and Nexant (a Bechtel Technology and Consulting Company) are jointly working to develop the proprietary process for

422

Records Schedule-UMTRA  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

WEQh!?ST FOP. RECOhD WEQh!?ST FOP. RECOhD ' 3ISPOSITIQN AClT H O R l N - - . (See Insrru~t,ons on reverse) 'c NATIOKAL ARCMVES and RECORDS ADMINISTRATION (MR) WASHINGTON, DC 20408 I . FROM ( A g e n c y or e s t a b l ~ s h m e n t ) , U. S . Denar-merit o f Enercy 2. MAJOR SU8OlVlSiON i 51 bu~uerque $net a t i i o n s O f ?ice (kL9 j 3. MINOR SUBDIVISION Urani urn !rp~tten pertaining to the disposition of its records and that the records roposed for disposal on the attached L , page s) are not now needed for the bus~ness of this agency or wil f not be needed after the retention enodss eci A ed; and that written concurrence from the General Accounting Office, under the pmvisions o

423

 

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Scope entails soil sampling at two volatile organic compoound (VOC) remedial action sites (Source Areas 3A and 3B) within P Area to confirm if soil Scope entails soil sampling at two volatile organic compoound (VOC) remedial action sites (Source Areas 3A and 3B) within P Area to confirm if soil remedial goals have been meet. 27 sampling locations are planned with up to 103 samples to be collected and analyzed for TCE and PCE. This work is being conducted as described in the P-Area Operable Unit Effectiveness Monitoring Plan, revision 1 (SRNS-RP-2010-00894). No clearing will be needed. Only minor mowing may be required at time sampling begins. Any IDW that is generated will be managed in accordance with ACP developed IDW management strategy document. This work is being conducted at sites where TCE and PCE are known to be present in the vadose zone and groundwater. No groundwater sampling is to be performed nor will groundwater wells be installed.

424

Wednesday, August 18, 2010  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

11 ~05 11 ~05 Project Information Project T itle: Movement of 5,000 bbl tank- Field Operations Date: 6115/10 DOE Code: 6722.022.00000 Contractor Code : 8067-103 Project Lead: Lyle Johnson 7Jit'5 IS /1- C't>ti)T/NtA.I11tD"W e;F- TK£ ~-rP Plfl.o 0 cc T To Project Overview /1-JC'Il..r.,s ~ K*T AJIITU! S7111!1'9GE AriZ G£o -rll'fl'l~tt~!Pt. 'PJU"dC c TS. 1. Bnef proJect description (include The project is to move the 5.000 bbl tank from the COC area to a site adjacent and north of the 5,000 bbl tank at the Tensleep battery. This tank will be moved in the same manner as the 5,000 bbl tank presently at anything that could 1mpact the the Tensleep battery that was previously also at the COC. A tank ring will be constructed at the Tensleep

425

Pacific Northwest National Laboratory Operated  

Office of Legacy Management (LM)

Pacific Pacific Northwest National Laboratory Operated by Battelle for the U .S. D ep artm ent of Energy PNWD-3914 Monticello Mill Tailings Site Macroinvertebrate Sampling for 2007 A.L. Bunn R.P. Mueller J.M. Brandenberger D .M. Wellman February 2008 Prepared for the U.S. Department of Energy under Contract DE-AC13-02GJ79491 DISCLAIMER This repon was prepared as an accoun t of work sponsored by an agency of the United States Government. Neither the United States Government nor any agency thereo f, no r Battelle Memorial Institute, no r any of their employees, makes an y warranty, express or implie d, or assumes any legal liability or responsibility for the accuracy, completeness, or usefulness of any information, ap paratus, produ ct, or p roce ss di sclos ed, or represen ts that its use would not in frin ge privat ely owned rights . Reference herein to any specific comm ercial product, process,

426

Household appliance choice: revision of REEPS behavioral models. Final report  

Science Conference Proceedings (OSTI)

This report describes the analysis of household decisions to install space heating, central cooling, and water heating in new housing as well as decisions to own freezers and second refrigerators. This analysis was conducted as part of the enhancements to the Residential End-Use Energy Planning System (REEPS) under EPRI project RP1918-1. The empirical models used in this analysis were the multinomial logit and its generalization the nested logit. The choice model parameters were estimated statistically on national and regional survey data. The results show that capital and operating costs are significant determinants of appliance market penetrations, and the relative magnitudes of the cost coefficients imply discount rates ranging from 3.4 to twenty-one percent. Several tests were conducted to examine the temporal and geographical stability of the key parameters. The estimated parameters have been incorporated into the REEPS computer code. The revised version of REEPS is now available on a limited release basis to EPRI member utilities for testing on their system.

Goett, A.A.

1984-02-01T23:59:59.000Z

427

Study of investigation-derived waste management options. Master's thesis  

Science Conference Proceedings (OSTI)

USAF is dedicated to the clean up of past releases of hazardous substances at its bases under the Installation Restoration Program (IRP) . Clean up decisions are based upon data produced from investigations. Large amounts of waste may be derived from investigations. Investigation-derived waste (IDW), especially that with a hazardous component, may pose significant health protection and regulatory compliance problems if neglected. This study identifies the status and the need for improvement of IDW management to avoid those problems. Information on the background of IDW management was collected through a review of environmental laws, waste management regulations, and existing guidance. Practical IDW management information was gleaned from conversations with iRP managers at twelve USAF bases around the country. This study revealed that IDW management needs improvement. All bases acknowledged IDW concerns and have adopted various methods to deal with them. However, current methods appear to rely more upon expediency rather than permanence. This study showed that critical protection and compliance issues are being overlooked. Development of specific IDW management guidance may better assure that critical issues are addressed. Waste minimization, Waste management, Environmental management, Nonhazardous wastes, Hazardous material, Solid wastes.

Mountain, B.C.

1993-09-01T23:59:59.000Z

428

Compilation of Diversity Factors and Schedules for Energy and Cooling Load Calculations, ASHRAE Research Project 1093, Preliminary Report, Literature Review and Database Search  

E-Print Network (OSTI)

In this report, the first report for the ASHRAE 1093-RP project, we present: (1) our extended literature search of methods used to derive load shapes and diversity factors in the U.S. and Europe, (2) a survey of available databases of monitored commercial end-use electrical data in the U.S. and Europe, and (3) a review of classification schemes of the commercial building stock listed in national standards and codes, and reported by researchers and utility projects. The findings in this preliminary report will help us in performing the next steps of the project where we will identify and test appropriate daytyping methods on relevant monitored data sets of lighting and equipment (and other surrogates for occupancy) to develop a library of diversity factors and schedules for use in energy and cooling load simulations. The goal of this project is to compile a library of schedules and diversity factors for energy and cooling load calculations in various types of indoor office environments in the U.S. and Europe. Two sets of diversity factors, one for peak cooling load calculations and one for energy calculations will be developed.

Abushakra, B.; Haberl, J. S.; Claridge, D. E.

1999-05-01T23:59:59.000Z

429

BRUSLIB and NETGEN: the Brussels nuclear reaction rate library and nuclear network generator for astrophysics  

E-Print Network (OSTI)

Nuclear reaction rates are quantities of fundamental importance in astrophysics. Substantial efforts have been devoted in the last decades to measure or calculate them. The present paper presents for the first time a detailed description of the Brussels nuclear reaction rate library BRUSLIB and of the nuclear network generator NETGEN so as to make these nuclear data packages easily accessible to astrophysicists for a large variety of applications. BRUSLIB is made of two parts. The first one contains the 1999 NACRE compilation based on experimental data for 86 reactions with (mainly) stable targets up to Si. The second part of BRUSLIB concerns nuclear reaction rate predictions calculated within a statistical Hauser-Feshbach approximation, which limits the reliability of the rates to reactions producing compound nuclei with a high enough level density. These calculations make use of global and coherent microscopic nuclear models for the quantities entering the rate calculations. The use of such models is utterly important, and makes the BRUSLIB rate library unique. A description of the Nuclear Network Generator NETGEN that complements the BRUSLIB package is also presented. NETGEN is a tool to generate nuclear reaction rates for temperature grids specified by the user. The information it provides can be used for a large variety of applications, including Big Bang nucleosynthesis, the energy generation and nucleosynthesis associated with the non-explosive and explosive hydrogen to silicon burning stages, or the synthesis of the heavy nuclides through the s-, alpha- and r-, rp- or p-processes.

M. Aikawa; M. Arnould; S. Goriely; A. Jorissen; K. Takahashi

2005-06-24T23:59:59.000Z

430

Hubble Space Telescope hot Jupiter Transmission Spectral Survey: detection of water in HAT-P-1b from Wide Field Camera 3 near-infrared spatial scan observations  

E-Print Network (OSTI)

We present Hubble Space Telescope near-infrared transmission spectroscopy of the transiting hot-Jupiter HAT-P-1b. We observed one transit with Wide Field Camera 3 using the G141 low-resolution grism to cover the wavelength range 1.087- 1.678 {\\mu}m. These time series observations were taken with the newly available spatial scan mode that increases the duty cycle by nearly a factor of two, thus improving the resulting photometric precision of the data. We measure a planet-to-star radius ratio of Rp/R*=0.11709+/-0.00038 in the white light curve with the centre of transit occurring at 2456114.345+/-0.000133 (JD). We achieve S/N levels per exposure of 1840 (0.061%) at a resolution of {\\Delta\\lambda}=19.2nm (R~70) in the 1.1173 - 1.6549{\\mu}m spectral region, providing the precision necessary to probe the transmission spectrum of the planet at close to the resolution limit of the instrument. We compute the transmission spectrum using both single target and differential photometry with similar results. The resultan...

Wakeford, H R; Deming, D; Gibson, N P; Fortney, J J; Burrows, A S; Ballester, G; Nikolov, N; Aigrain, S; Henry, G; Knutson, H; Etangs, A Lecavelier des; Pont, F; Showman, A P; Vidal-Madjar, A; Zahnle, K

2013-01-01T23:59:59.000Z

431

Physics with Rare Isotope Beams  

Science Conference Proceedings (OSTI)

Using stable and radioactive beams provided by ATLAS nuclear reactions of special interest in astrophysics have been studied with emphasis on breakout from the hot CNO cycle to the rp-process. The masses of nuclear fragments provided by a strong fission source have been measured in order to help trace the path of the r process. 8Li ions produced by the d(7Li,8Li)n reaction have been trapped and the electrons and alphas emitted in the ensuing beta-decay measured. The neutrino directions were therefore determined, which leads to a measurement of the electron-neutrino correlation. The energies and kinematics are such that a sensitive search for any tensor admixture could be performed and an upper limit of 0.6% was placed on any such admixture. Earlier work on the electromagnetic form factors of the proton was extended. Graduate students were active participants in all of these eperiments, which formed the basis for six PhD theses.

Segel, Ralph E. [Northwestern University

2013-11-08T23:59:59.000Z

432

Hard instances for satisfiability and quasi-one-way functions  

E-Print Network (OSTI)

We give an efficient algorithm that takes as input any (probabilistic) polynomial time algorithm A which purports to solve SAT and finds, for infinitely many input lengths, SAT formulas ? and witnesses w such that A claims ? is unsatisfiable, but w is a satisfying assignment for ? (assuming NP ? ? RP). This solves an open problem posed in the work of Gutfreund, Shaltiel, and Ta-Shma (CCC 2005). Following Gutfreund et al., we also extend this to give an efficient sampling algorithm (a quasi-hard sampler) which generates hard instance/witness pairs for all algorithms running in some fixed polynomial time. We ask how our sampling algorithm relates to various cryptographic notions. We show that our sampling algorithm gives a simple construction of quasi-one-way functions, a weakened notion of standard one-way functions. We also investigate the possibility of obtaining pseudorandom generators from our quasi-one-way functions and show that a large class of reductions that work in the standard setting must fail.

Andrej Bogdanov; Kunal Talwar; Andrew Wan

2009-01-01T23:59:59.000Z

433

New hot-water use data for commercial buildings  

Science Conference Proceedings (OSTI)

This article reports that researchers have found that hot water usage in certain commercial buildings may be significantly higher than designers expect. ASHRAE Technical Committee 6.6, Service Water Heating, recognized the need for a comprehensive compilation and evaluation of available hot water usage information in residential and commercial installations. The bulk of the commercial building hot water demand and sizing information presented in Chapter 44 of the 1991 ASHRAE Handbook--HVAC Application is based on a comprehensive study published in 1969. However, information received by members of TC 6.6 and data appearing in some of the current literature suggest that the Handbook values may be too conservative. Because of conflicting information in the literature and possible variations in lifestyles and use patterns since the Handbook values were originally published, ASHRAE sponsored research project RP-600 to study and review these issues. In this research project, domestic hot water consumption was monitored at five separate commercial buildings in four building category types: one nursing home, two dormitories (one coed and one women's), one full-service restaurant and one hotel.

Thrasher, W.H.; DeWerth, D.W. (American Gas Association Lab., Cleveland, OH (United States))

1994-09-01T23:59:59.000Z

434

Pricing of electricity in Indonesia  

SciTech Connect

The objectives of this study are 1) to establish a sound theoretical basis for the determinants of electricity demand in Indonesia, 2) to measure the welfare losses of existing electricity pricing, and 3) to suggest a method of reducing these welfare losses. An econometric model for electricity demand is estimated using pooled time-series of fifteen regions in Indonesia covering the period 1970-1979. The short run price elasticities for both residential and industrial/business sectors are found to be inelastic, while the long run price elasticities for these sectors are found to be quite elastic with a value of -.61 for the residential sector and of -1.1 for the industrial/business sector. Income elasticity is .8 in the short run and around 1.00 for the long run. The exposure variable that captures the accessibility of electricity, has long run elasticity of 1.00 for the residential sector and less than 1.00 for the industrial/business sector. Due to distributional considerations, the 1980's electricity rate was set below its efficient level, and has created a welfare loss of Rp.8273.23 million per month. This accounts for 36.03% of the monthly electricity revenue. A rebate mechanism is recommended in this study, which provides a way to mitigate conflicting aspects of efficiency and equity.

Amarullah, M.

1983-01-01T23:59:59.000Z

435

KELT-6b: A P~7.9 d Hot Saturn Transiting a Metal-Poor Star with a Long-Period Companion  

E-Print Network (OSTI)

We report the discovery of KELT-6b, a mildly-inflated Saturn-mass planet transiting a metal-poor host. The initial transit signal was identified in KELT-North survey data, and the planetary nature of the occulter was confirmed using a combination of follow-up photometry, high-resolution imaging, high-resolution spectroscopy, and precise radial velocity measurements. The fiducial model from a global analysis including constraints from isochrones indicates that the V=10.38 host star (TYC 2532-556-1) is a mildly evolved, late-F star with T_eff=6102 \\pm 43 K, log(g_*)=4.07_{-0.07}^{+0.04} and [Fe/H]=-0.28 \\pm 0.04, with an inferred mass M_*=1.09 \\pm 0.04 M_sun and radius R_*=1.58_{-0.09}^{+0.16} R_sun. The planetary companion has mass M_p=0.43 \\pm 0.05 M_Jup, radius R_p=1.19_{-0.08}^{+0.13} R_Jup, surface gravity log(g_p)=2.86_{-0.08}^{+0.06}, and density rho_p=0.31_{-0.08}^{+0.07} g cm^{-3}. The planet is on an orbit with semimajor axis a=0.079 \\pm 0.001 AU and eccentricity e=0.22_{-0.10}^{+0.12}, which is rough...

Collins, Karen A; Beatty, Thomas G; Siverd, Robert J; Gaudi, B Scott; Pepper, Joshua; Kielkopf, John F; Johnson, John Asher; Howard, Andrew W; Fischer, Debra A; Manner, Mark; Bieryla, Allyson; Latham, David W; Fulton, Benjamin J; Gregorio, Joao; Buchhave, Lars A; Jensen, Eric L N; Stassun, Keivan G; Penev, Kaloyan; Crepp, Justin R; Hinkley, Sasha; Street, Rachel A; Cargile, Phillip; Mack, Claude E; Oberst, Thomas E; Avril, Ryan L; Mellon, Samuel N; McLeod, Kim K; Penny, Matthew T; Stefanik, Robert P; Berlind, Perry; Calkins, Michael L; Mao, Qingqing; Richert, Alexander J W; DePoy, Darren L; Esquerdo, Gilbert A; Gould, Andrew; Marshall, Jennifer L; Oelkers, Ryan J; Pogge, Richard W; Trueblood, Mark; Trueblood, Patricia

2013-01-01T23:59:59.000Z

436

The TOTEM Detector at LHC  

E-Print Network (OSTI)

The TOTEM experiment, small in size compared to the others at the LHC, is dedicated to the measurement of the total proton-proton cross-section with the luminosity-independent method and to the study of elastic and diffractive scattering. To achieve optimum forward coverage for charged particles emitted by the pp collisions in the interaction point IP5, two tracking telescopes, T1 and T2, are installed on each side in the pseudo-rapidity region between 3.1 and 6.5, and Roman Pot (RP) stations are placed at distances of 147m and 220m from IP5. The telescope closest to the interaction point (T1, centered at z = 9 m) consists of Cathode Strip Chambers (CSC), while the second one (T2, centered at 13.5 m), makes use of Gas Electron Multipliers (GEM). The proton detectors in the RPs are silicon devices designed by TOTEM with the specific objective of reducing down to a few tens of microns the insensitive area at the edge. High efficiency as close as possible to the physical detector boundary is an essential feature...

Ruggiero, G; Aspell, P; Atanassov, I; Avati, V; Berardi, V; Berretti, M; Bozzo, M; Brcken, E; Buzzo, A; Cafagna, F; Calicchio, M; Catanesi, M G; Ciocci, M A; Csand, M; Csrg, T; Deile, M; Dnes, E; Dimovasili, E; Doubek, M; Eggert, K; Ferro, F; Garcia, F; Giani, S; Greco, V; Grzanka, L; Heino, J; Hilden, T; Janda, M; Kaspar, J; Kopal, J; Kundrt, V; Kurvinen, K; Lami, S; Latino, G; Lauhakangas, R; Lippmaa, E; Lokajcek, M; Lo Vetere, M; Lucas Rodriguez, F; Macr, M; Magazz, G; Minutoli, S; Niewiadomski, H; Notarnicola, G; Novak, T; Oliveri, E; Oljemark, F; Orava, R; Oriunno, M; sterberg, K; Pedreschi, E; Petjjrvi, J; Quinto, M; Radermacher, E; Radicioni, E; Ravotti, F; Robutti, E; Ropelewski, L; Rummel, A; Saarikko, H; Sanguinetti, G; Santroni, A; Scribano, A; Sette, G; Snoeys, W; Spearman, W; Spinella, F; Ster, A; Taylor, C; Trummal, A; Turini, N; Vacek, V; Vitek, M; Whitmore, J; Wu, J

2010-01-01T23:59:59.000Z

437

A confirmative spin-parity assignment for the key 6.15 MeV state in $^{18}$Ne of astrophysical importance  

E-Print Network (OSTI)

Proton resonant states in $^{18}$Ne have been investigated by the resonant elastic scattering of $^{17}$F+$p$. The $^{17}$F beam was separated by the CNS radioactive ion beam separator (CRIB), and bombarded a thick H$_2$ gas target at 3.6 MeV/nucleon. The recoiled light particles were measured by using three sets of ${\\Delta}$E-E Si telescope at scattering angles of $\\theta$$_{lab}$$\\approx 3^\\circ$, 10$^\\circ$ and 18$^\\circ$, respectively. Four resonances, {\\it i.e.}, at $E_{x}$=6.15, 6.30, 6.85, and 7.05 MeV, were observed clearly. By $R$-matrix analysis of the excitation functions, $J^{\\pi}$=1$^-$ was firmly assigned to the 6.15 MeV state which is a key state in calculating the reaction rate of $^{14}$O($\\alpha$,$p$)$^{17}$F reaction. This reaction was thought to be one of the most probable key reactions for the breakout from the hot-CNO cycle to the $rp$-process in type I x-ray bursts In addition, a new excited state observed at $E_{x}$=6.85 MeV was tentatively assigned as 0$^{-}$, which could be the analog state of 6.880 MeV, 0$^{-}$ in mirror $^{18}$O.

J. Hu; J. J. He; S. W. Xu; H. Yamaguchi; K. David; P. Ma; J. Su; H. W. Wang; T. Nakao; Y. Wakabayashi; T. Teranishi; J. Y. Moon; H. S. Jung; T. Hashimoto; A. Chen; D. Irvine; S. Kubono

2013-06-17T23:59:59.000Z

438

Native SrTiO3 (001) surface layer from resonant Ti L2,3 reflectance spectroscopy  

SciTech Connect

We quantitatively model resonant Ti L2,3 reflectivity Rs,p(q, hn) from several SrTiO3 (001) single crystals having different initial surface preparations and stored in ambient conditions before and between measurements. All samples exhibit unexpected 300 K Rs(hn) - Rp(hn) anisotropy corresponding to weak linear dichroism and tetragonal distortion of the TiO6 octahedra indicating a surface layer with properties different from cubic SrTiO3. Oscillations in Rs(q) confirm a ubiquitous surface layer 2-3 nm thick that evolves over a range of time scales. Resonant optical constant spectra derived from Rs,p(hn) assuming a uniform sample are refined using a single surface layer to fit measured Rs(q). Differences in surface layer and bulk optical properties indicate that the surface is significantly depleted in Sr and enriched in Ti and O. While consistent with the tendency of SrTiO3 surfaces toward non-stoichiometry, this layer does not conform simply to existing models for the near surface region and apparently forms via room temperature surface reactions with the ambient. This new quantitative spectral modeling approach is generally applicable and has potential to study near-surface properties of a variety of systems with unique chemical and electronic sensitivities.

Valvidares, Manuel; Huijben, Mark; Yu, Pu; Ramesh, Ramamoorthy; Kortright, Jeffrey

2010-11-03T23:59:59.000Z

439

A HPLC method for the quantification of butyramide and acetamide at ppb levels in hydrogeothermal waters  

DOE Green Energy (OSTI)

A quantitative analytical method to determine butyramide and acetamide concentrations at the low ppb levels in geothermal waters has been developed. The analytes are concentrated in a preparation step by evaporation and analyzed using HPLC-UV. Chromatographic separation is achieved isocratically with a RP C-18 column using a 30 mM phosphate buffer solution with 5 mM heptane sulfonic acid and methanol (98:2 ratio) as the mobile phase. Absorbance is measured at 200 nm. The limit of detection (LOD) for BA and AA were 2.0 {mu}g L{sup -1} and 2.5 {mu}g L{sup -1}, respectively. The limit of quantification (LOQ) for BA and AA were 5.7 {mu}g L{sup -1} and 7.7 {mu}g L{sup -1}, respectively, at the detection wavelength of 200 nm. Attaining these levels of quantification better allows these amides to be used as thermally reactive tracers in low-temperature hydrogeothermal systems.

Gracy Elias; Earl D. Mattson; Jessica E. Little

2012-01-01T23:59:59.000Z

440

Blood and water; the archaeological excavation and historical analysis of the Wreck of the Industry, a North-American transport sloop chartered by the British army at the end of the Seven Years' War: British colonial navigation and trade to supply Spanish Florida in the eighteenth century  

E-Print Network (OSTI)

In the 10-mer RNA duplex model system a 4-isocyano TEMPO spin-label is individually attached to one strand and two strands are annealed to measure distances. This methodology is limited to systems in which two oligonucleotides are annealed together. To circumvent this limitation and also to explore single-strand dynamics a new methodology was implemented, double spin-labeling. Double spin-labeled single-stranded RNA was investigated as a single-strand and within a duplex via MALDI-TOF-MS, EPR spectroscopy and RP-HPLC. A double spin-labeling strategy in this work will be applicable to large complex RNAs like Group I intron of Tetrahymena thermophilia. Captain Daniel Lawrence, was one of four sloops detailed to serve as a transport to supply the British Florida garrisons. The Industry ran aground on the bar outside of St. Augustine's harbour on May 6, 1764. The transport was carrying six-pound cannons, ammunition and artificer's tools. Further investigation of documents describing eighteenth-century trade and shipping to St. Augustine led to the discovery that the Lawrence family of sea captains provided a vital link between British New York and Spanish St. Augustine. An examination of the materials recovered from Site 8SJ3478 sheds light on exactly what a particular vessel carried during a period of transition in Florida's history.

Franklin, Marianne

2005-12-01T23:59:59.000Z

Note: This page contains sample records for the topic "retinitis pigmentosa rp" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


441

Chemical decontamination technical resources at Los Alamos National Laboratory (2008)  

SciTech Connect

This document supplies information resources for a person seeking to create planning or pre-planning documents for chemical decontamination operations. A building decontamination plan can be separated into four different sections: Pre-planning, Characterization, Decontamination (Initial response and also complete cleanup), and Clearance. Of the identified Los Alamos resources, they can be matched with these four sections: Pre-planning -- Dave Seidel, EO-EPP, Emergency Planning and Preparedness; David DeCroix and Bruce Letellier, D-3, Computational fluids modeling of structures; Murray E. Moore, RP-2, Aerosol sampling and ventilation engineering. Characterization (this can include development projects) -- Beth Perry, IAT-3, Nuclear Counterterrorism Response (SNIPER database); Fernando Garzon, MPA-11, Sensors and Electrochemical Devices (development); George Havrilla, C-CDE, Chemical Diagnostics and Engineering; Kristen McCabe, B-7, Biosecurity and Public Health. Decontamination -- Adam Stively, EO-ER, Emergency Response; Dina Matz, IHS-IP, Industrial hygiene; Don Hickmott, EES-6, Chemical cleanup. Clearance (validation) -- Larry Ticknor, CCS-6, Statistical Sciences.

Moore, Murray E [Los Alamos National Laboratory

2008-01-01T23:59:59.000Z

442

On the temperature profile of radiatively efficient geometrically thin disks in black hole binaries with the ASCA GIS  

E-Print Network (OSTI)

X-ray spectra of black hole binaries(BHBs) in the high/soft state were studied comprehensively by using ASCA GIS data, and partially RXTE PCA data. A mathematical disk model was applied to several BHBs to see if the observed accretion disk temperature profile was consistent with that expected from the standard accretion disk model. This model is called p-free disk, and assumes that the spectrum is composed of multi-temperature blackbody emission of which the local temperature T(r) at radius r is given by T(r) ~ r^-p with p being a positive free parameter. The standard disk roughly requires p~3/4, while a small deviation is expected depending on the inner boundary conditions, general relativistic effects and disk vertical structures.Our sample objects included LMC X-1, LMC X-3, XTE J2012+381, and GRO J1655-40. During the ASCA observations, these BHBs showed characteristics of the standard high/soft state. Under the standard modeling of high-state black hole binaries, the sources show Tin=0.76-1.17keV, the disk...

Kubota, A; Makishima, K; Nakazawa, K; Kubota, Aya; Ebisawa, Ken; Makishima, Kazuo; Nakazawa, Kazuhiro

2005-01-01T23:59:59.000Z

443

Offshore sample disturbance and its effect on piling design  

Science Conference Proceedings (OSTI)

Recent experiments by the authors have indicated that motorized miniature vane and fall cone test results are sensitive to the testing location within the sample. Undrained shear strength values obtained from tests conducted near the tip of the sampling tubes (1 to 2 diameters within) have been shown to be consistently low when compared to results obtained at selected points further into the tube. This study presents the results of a marine geotechnical investigation which clearly confirm this observation. Also presented are comparisons of mini-vane strengths to those of the fall cone and an illustration of the effect of using ''near the tip''undrained shear strength values on required piling lengths computed by API RP 2 A guidelines. It is found that the quantitative effect of testing soil or undrained shear strength at the sampling tube tip has been investigated for a marine clay soil at a specific site in the Gulf of Mexico. It is shown that the standard practice of using miniature vane strengths from the tube tip underestimates the in-tube undrained shear strength by about 10 to 30 % for this case. 5 refs.

Dover, A.R.; Rainey, W.S.; Thompson, G.R.

1981-10-12T23:59:59.000Z

444

Evaluation of the Relative Importance of Parameters Influencing Perforation Cleanup  

Science Conference Proceedings (OSTI)

Completion of cased and cemented wells by shaped-charge perforation results in damage to the formation, which can significantly reduce well productivity. Typically, underbalanced conditions are imposed during perforation in an effort to remove damaged rock and shaped-charge debris from the perforation tunnel. Immediately after the shaped-charge jet penetrates the formation, there is a transient surge of fluid from the formation through the perforation and into the well bore. Experimental evidence suggests that it is this transient pressure surge that leads to the removal of damaged rock and charge debris leaving an open perforation tunnel. We have developed a two-stage computational model to simulate the perforation process and subsequent pressure surge and debris removal. The first stage of the model couples a hydrocode with a model of stress-induced permeability evolution to calculate damage to the formation and the resulting permeability field. The second stage simulates the non-Darcy, transient fluid flow from the formation and removes damaged rock and charge debris from the perforation tunnel. We compare the model to a series of API RP43 section 4 flow tests and explore the influence of fluid viscosity and rock strength on the final perforation geometry and permeability.

Detwiler, R L; Morris, J P; Karacan, C O; Halleck, P M; Hardesty, J

2003-10-22T23:59:59.000Z

445

Literature Review of Uncertainty of Analysis Methods (Inverse Model Toolkit), Report to the Texas Commission on Environmental Quality  

E-Print Network (OSTI)

This report reviews the reported uncertainty of ASHRAEs Inverse Model Toolkit (IMT) analysis method and the linear, and change-point linear algorithms that it uses by reviewing the published literature on the related accuracy of IMT and its algorithms versus other well-accepted statistical analysis tools, such as SAS. This report begins with a review of the history of the IMT, and the linear and change-point linear models. Then it reviews the published comparisons of the IMT and other analysis software, relying heavily on the accuracy testing that was performed as part of ASHRAEs Research Project 1050-RP. It also includes a detailed description of the basic algorithms and an example of the IMT weather-normalization analysis. In summary, from the literature it was found that the algorithms in the IMT almost exactly reproduce the same regression analysis one would get by running any one of the programs that it was compared against (i.e., usually to several significant digits). Therefore, it can be concluded that the IMT is accurate, when it is called upon to perform weather normalized regressions for modeling building energy use.

Haberl, J. S.; Cho, S.

2004-01-01T23:59:59.000Z

446

A Small-Scale Safety Test for Initiation Components  

SciTech Connect

We have developed a small-scale safety test for initiation train components. A low-cost test was needed to assess the response of initiation components to an abnormal shock environment and to detect changes in the sensitivity of initiation components as they age. The test uses a disk of Detasheet to transmit a shock through a PMMA barrier into a the test article. A schematic drawing of the fixture is shown. The 10-cm-diameter disk of 3-mm-thick Detasheet, initiated at its center by a RISI, RP detonator, produces a shock wave that is attenuated by a variable-thickness PMMA spacer (gap). Layers of metal and plastic above the test article and the material surrounding the test article may be chosen to mock up the environment of the test article at its location in a warhead. A metal plate at the bottom serves as a witness plate to record whether or not the test article detonated. For articles containing a small amount of explosive, it can be difficult to determine whether or not a detonation has occurred. In such cases, one can use a pressure transducer or laser velocimeter to detect the shock wave from the detonation of the article. The assembly is contained in a 10-cm-ID section of PVC pipe and fired in a containment vessel rated at 100 g. Test results are given for a hemispherical, exploding-bridgewire (EBW) detonator.

Cutting, J; Chow, C; Chau, H; Hodgin, R; Lee, R

2002-04-22T23:59:59.000Z

447

Models for Type I X-Ray Bursts with Improved Nuclear Physics  

DOE Green Energy (OSTI)

Multi-zone models of Type I X-ray bursts are presented that use an adaptive nuclear reaction network of unprecedented size, up to 1300 isotopes, for energy generation and include the most recent measurements and estimates of critical nuclear physics. Convection and radiation transport are included in calculations that carefully follow the changing composition in the accreted layer, both during the bursts themselves and in their ashes. Sequences of bursts, up to 15 in one case, are followed for two choices of accretion rate and metallicity, up to the point where quasi-steady state is achieved. For M = 1.75 x 10{sup -9} M{sub {circle_dot}} yr{sup -1} (and M = 3.5 x 10{sup -10} M{sub {circle_dot}} yr{sup -1}, for low metallicity), combined hydrogen-helium flashes occur. These bursts have light curves with slow rise times (seconds) and long tails. The rise times, shapes, and tails of these light curves are sensitive to the efficiency of nuclear burning at various waiting points along the rp-process path and these sensitivities are explored. Each displays ''compositional inertia'' in that its properties are sensitive to the fact that accretion occurs onto the ashes of previous bursts which contain left-over hydrogen, helium and CNO nuclei.

Woosley, S E; Heger, A; Cumming, A; Hoffman, R D; Pruet, J; Rauscher, T; Schatz, H; Brown, B A; Wiescher, M; Fisker, J L

2004-02-02T23:59:59.000Z

448

Evaluation of Automated Model Calibration Techniques for Residential Building Energy Simulation  

SciTech Connect

This simulation study adapts and applies the general framework described in BESTEST-EX (Judkoff et al 2010) for self-testing residential building energy model calibration methods. BEopt/DOE-2.2 is used to evaluate four mathematical calibration methods in the context of monthly, daily, and hourly synthetic utility data for a 1960's-era existing home in a cooling-dominated climate. The home's model inputs are assigned probability distributions representing uncertainty ranges, random selections are made from the uncertainty ranges to define 'explicit' input values, and synthetic utility billing data are generated using the explicit input values. The four calibration methods evaluated in this study are: an ASHRAE 1051-RP-based approach (Reddy and Maor 2006), a simplified simulated annealing optimization approach, a regression metamodeling optimization approach, and a simple output ratio calibration approach. The calibration methods are evaluated for monthly, daily, and hourly cases; various retrofit measures are applied to the calibrated models and the methods are evaluated based on the accuracy of predicted savings, computational cost, repeatability, automation, and ease of implementation.

Robertson, J.; Polly, B.; Collis, J.

2013-09-01T23:59:59.000Z

449

Treatability study of Tank E-3-1 waste: mixed waste stream SR-W049  

Science Conference Proceedings (OSTI)

Treatability studies were conducted for tank E-3-1 waste which was previously characterized in WSRC-RP-87-0078. The waste was determined to be mixed waste because it displayed the characteristic of metal toxicity for Hg and Cr and was also contaminated with low levels of radionuclides. Two types of treatments for qualifying this waste suitable for land disposal were evaluated: ion exchange and stabilization with hydraulic materials (portland cement, slag and magnesium phosphate cement). These treatments were selected for testing because: (1) Both treatments can be carried out as in-drum processes., (2) Cement stabilization is the RCRA/LDR best developed available technology (BDAT) for Hg (less than 280 mg/L) and for Cr., and (3) Ion exchange via Mag-Sep is a promising alternative technology for in drum treatment of liquid wastes displaying metal toxicity. Cement stabilization of the E-3-1 material ( supernate and settled solids) resulted in waste forms which passed the TCLP test for both Hg and Cr. However, the ion exchange resins tested were ineffective in removing the Hg from this waste stream. Consequently, cement stabilization is recommended for a treatment of the five drums of the actual waste.

Langton, C.A. [Westinghouse Savannah River Company, AIKEN, SC (United States)

1997-08-21T23:59:59.000Z

450

Methods and systems for integrating fluid dispensing technology with stereolithography  

DOE Patents (OSTI)

An integrated system and method of integrating fluid dispensing technologies (e.g., direct-write (DW)) with rapid prototyping (RP) technologies (e.g., stereolithography (SL)) without part registration comprising: an SL apparatus and a fluid dispensing apparatus further comprising a translation mechanism adapted to translate the fluid dispensing apparatus along the Z-, Y- and Z-axes. The fluid dispensing apparatus comprises: a pressurized fluid container; a valve mechanism adapted to control the flow of fluid from the pressurized fluid container; and a dispensing nozzle adapted to deposit the fluid in a desired location. To aid in calibration, the integrated system includes a laser sensor and a mechanical switch. The method further comprises building a second part layer on top of the fluid deposits and optionally accommodating multi-layered circuitry by incorporating a connector trace. Thus, the present invention is capable of efficiently building single and multi-material SL fabricated parts embedded with complex three-dimensional circuitry using DW.

Medina, Francisco (El Paso, TX); Wicker, Ryan (El Paso, TX); Palmer, Jeremy A. (Albuquerque, NM); Davis, Don W. (Albuquerque, NM); Chavez, Bart D. (Albuquerque, NM); Gallegos, Phillip L. (Albuquerque, NM)

2010-02-09T23:59:59.000Z

451

Enrichment of canine gestation and lactation diets with n-3 polyunsaturated fatty acids to support neurologic development  

E-Print Network (OSTI)

Long-chain polyunsaturated fatty acids (LCPUFA) are essential for proper neural and retinal development in many mammalian species. One objective of this research was to investigate the effects of dietary ?-linolenic acid (ALA) and LCPUFA on the fatty acid composition of canine plasma phospholipids (PL) and milk during the gestation and lactation periods. The fatty acid composition of plasma PL and the retinal development of puppies reared on the same experimental diets as their mothers were also investigated. Enriching the canine gestation/lactation diet with ALA (6.8% DM) does not result in enrichment of docosahexaenoic acid (DHA) in the milk. From this data it can be inferred that peroxisomal elongation and desaturation of LCPUFA does not occur in canine mammary tissue. Dose responses of linoleic acid (LA), ALA and DHA were observed in the plasma of adult dogs during gestation and lactation and in puppies during both the suckling and post-weaning periods. Plasma PL fatty acid data from puppies indicate that canine neonates are capable of synthesizing LCPUFA from ALA, but that plasma enrichment of the newly-synthesized DHA does not compare with that obtained from preformed DHA in the diet. Visual function was assessed via electroretinography (ERG) in 12-wk old canines. One-way ANOVA revealed significantly better visual performance in dogs fed the highest amounts of n-3 LCPUFA. Puppies in this group demonstrated the greatest rod response as measured by the amplitude and implicit time of the a-wave. Neonates reared on the lowest dietary levels of both ALA and n-3 LCPUFA exhibited the poorest visual function. A novel parameter devised in this study was the threshold intensity, which was the initial intensity at which the a-wave was detectable. Again, puppies consuming the greatest concentrations of n-3 LCPUFA responded significantly sooner, i.e. exhibited greater rod sensitivity, than other diet groups. The findings of this research underscore the importance of preformed n-3 LCPUFA in the diet, rather than ALA, as a means of enriching neural tissues in DHA during the developmental period. Moreover, dietary DHA appears to be related to improved visual performance in developing canines.

Heinemann, Kimberly Michele

2004-08-01T23:59:59.000Z

452

Operation Redwing. Project 4. 1. Chorioretinal burns  

SciTech Connect

This Redwing project was designed to furnish supplemental information on the requirements for protection against retinal burns, using both rabbits and monkeys as experimental animals. Chorioretinal burns were produced by various segments of the thermal pulse. This was accomplished by two series of time-fractionating shutters. The first group, the early closing shutters, were open at time zero and closed at increasing intervals of time. The second series, the delayed-opening shutters, were closed at time zero and subsequently opened for preselected time increments during the flash. The feasibility of protection by fixed-density optical filters was explored. Two types of protective electronic shutters were field tested. Additional objectives were to: (1) determine whether blink reflexes would prevent chorioretinal burns; (2) ascertain which portions of the time-intensity pulse can produce thermal injury to the retina and choroid of the eye; (3) determine the time required for blink reflex in rabbits and monkeys exposed to the extreme light intensity of the nuclear detonations; (4) explore the feasibility of ocular protection by means of fixed-density optical filters or combinations of filters; and (5) tests, under field conditions, protective shutter devices that are in the developmental state and are designed to close more rapidly than the blink reflex.

Fixott, R.; Pickering, J.E.; Williams, D.B.; Brown, D.V.L.; Rose, H.W.

1985-09-01T23:59:59.000Z

453

Performance of a MEMS-based AO-OCT system using Fourier Reconstruction  

Science Conference Proceedings (OSTI)

Adaptive optics (AO) and optical coherence tomography (OCT) are powerful imaging modalities that, when combined, can provide high-resolution (3.5 {micro}m isotropic), 3-D images of the retina. The AO-OCT system at UC Davis has demonstrated the utility of this technology for microscopic, volumetric, in vivo retinal imaging. The current system uses an AOptix bimorph deformable mirror (DM) for low-order, high-stroke correction and a 140-actuator Boston Micromachines DM for high-order correction. Developments to improve performance or functionality of the instrument are on-going. Based on previous work in system characterization we have focused on improved AO control. We present preliminary results and remaining challenges for a newly implemented Fourier transform reconstructor (FTR). The previously reported error budget analysis is also reviewed and updated, with consideration of how to improve both the amount of residual error and the robustness of the system. Careful characterization of the AO system will lead to improved performance and inform the design of future systems.

Evans, J; Zawadzki, R; Jones, S; Olivier, S; Werner, J S

2009-01-21T23:59:59.000Z

454

Science and Technology Review October/November 2009  

SciTech Connect

This month's issue has the following articles: (1) Award-Winning Collaborations Provide Solutions--Commentary by Steven D. Liedle; (2) Light-Speed Spectral Analysis of a Laser Pulse--An optical device inspects and stops potentially damaging laser pulses; (3) Capturing Waveforms in a Quadrillionth of a Second--The femtoscope, a time microscope, improves the temporal resolution and dynamic range of conventional recording instruments; (4) Gamma-Ray Spectroscopy in the Palm of Your Hand--A miniature gamma-ray spectrometer provides increased resolution at a reduced cost; (5) Building Fusion Targets with Precision Robotics--A robotic system assembles tiny fusion targets with nanometer precision; (6) ROSE: Making Compiler Technology More Accessible--An open-source software infrastructure makes powerful compiler techniques available to all programmers; (7) Restoring Sight to the Blind with an Artificial Retina--A retinal prosthesis could restore vision to people suffering from eye diseases; (8) Eradicating the Aftermath of War--A remotely operated system precisely locates buried land mines; (9) Compact Alignment for Diagnostic Laser Beams--A smaller, less expensive device aligns diagnostic laser beams onto targets; and (10) Securing Radiological Sources in Africa--Livermore and other national laboratories are helping African countries secure their nuclear materials.

Bearinger, J P

2009-08-21T23:59:59.000Z

455

Rhodopsin kinetics in the cat retina  

SciTech Connect

The bleaching and regeneration of rhodopsin in the living cat retina was studied by means of fundus reflectometry. Bleaching was effected by continuous light exposures of 1 min or 20 min, and the changes in retinal absorbance were measured at 29 wavelengths. For all of the conditions studied (fractional bleaches of from 65 to 100%), the regeneration of rhodopsin to its prebleach levels required greater than 60 min in darkness. After the 1-min exposures, the difference spectra recorded during the first 10 min of dark adaptation were dominated by photoproduct absorption, and rhodopsin regeneration kinetics were obscured by these intermediate processes. Extending the bleaching duration to 20 min gave the products of photolysis an opportunity to dissipate, and it was possible to follow the regenerative process over its full time-course. It was not possible, however, to fit these data with the simple exponential function predicted by first-order reaction kinetics. Other possible mechanisms were considered and are presented in the text. Nevertheless, the kinetics of regeneration compared favorably with the temporal changes in log sensitivity determined electrophysiologically by other investigators. Based on the bleaching curve for cat rhodopsin, the photosensitivity was determined and found to approximate closely the value obtained for human rhodopsin; i.e., the energy Ec required to bleach 1-e-1 of the available rhodopsin was 7.09 log scotopic troland-seconds (corrected for the optics of the cat eye), as compared with approximately 7.0 in man.

Ripps, H.; Mehaffey, L.; Siegel, I.M.

1981-03-01T23:59:59.000Z

456

Oxygen Transport Membranes  

Science Conference Proceedings (OSTI)

The focus of this research was to develop new membrane materials by synthesizing different compounds and determining their defect structures, crystallographic structures and electrical properties. In addition to measuring electrical conductivity, oxygen vacancy concentration was also evaluated using thermogravimetry, Neutron diffraction and Moessbauer Spectroscopy. The reducing conditions (CO{sub 2}/CO/H{sub 2} gas mixtures with steam) as encountered in a reactor environment can be expected to have significant influence on the mechanical properties of the oxides membranes. Various La based materials with and without Ti were selected as candidate membrane materials for OTM. The maximum electrical conductivity of LSF in air as a function of temperature was achieved at Oxygen occupancy in LSF was estimated using Neutron diffractometry and Moessbauer Spectroscopy by measuring magnetic moment changes depending on the Fe{sup 3+} and Fe{sup 4+} ratio. After extensive studies of candidate materials, lanthanum ferrites (LSF and LSFT) were selected as the favored materials for the oxygen transport membrane (OTM). LSF is a very good material for an OTM because of its high electronic and oxygen ionic conductivity if long term stability and mechanical strength are improved. LSFT not only exhibits p-type behavior in the high oxygen activity regime, but also has n-type conduction in reducing atmospheres. Higher concentrations of oxygen vacancies in the low oxygen activity regime may improve the performance of LSFT as an OTM. The hole concentration is related to the difference in the acceptor and donor concentration by the relation p = [Sr'{sub La}]-[Ti{sm_bullet}{sub Fe}]. The chemical formulation predicts that the hole concentration is, p = 0.8-0.45 or 0.35. Experimental measurements indicated that p is about {approx} 0.35. The activation energy of conduction is 0.2 eV which implies that LSCF conducts via the small polaron conduction mechanism. Scanning transmission electron microscopy (STEM) and electron energy loss spectroscopy (EELS) were used to develop strategies to detect and characterize vacancy creation, dopant segregations and defect association in the oxygen conducting membrane material. The pO{sub 2} and temperature dependence of the conductivity, non-stoichiometry and thermal-expansion behavior of compositions with increasing complexity of substitution on the perovskite A and B sites were studied. Studies with the perovskite structure show anomalous behavior at low oxygen partial pressures (oxygen equilibration kinetics arises from two different mechanisms. In the first, a two phase region occurs between an oxygen vacancy ordered phase such as brownmillerite SrFeO{sub 2.5} and perovskite SrFeO{sub 3-x}. The slow kinetics is associated with crossing the two phase region. The width of the miscibility gap decreases with increasing temperature and consequently the effect is less pronounced at higher temperature. The preferred kinetic pathway to reduction of perovskite ferrites when the vacancy concentration corresponds to the formation of significant concentrations of Fe{sup 2+} is via the formation of a Ruddlesden-Popper (RP) phases as clearly observed in the case of La{sub 0.5}Sr{sub 0.5}FeO{sub 3-x} where LaSrFeO{sub 4} is found together with Fe. In more complex compositions, such as LSFTO, iron or iron rich phases are observed locally with no evidence for the presence of discrete RP phase. Fracture strength of tubular perovskite membranes was determined in air and in reducing atmospheric conditions. The strength of the membrane decreased with temperature and severity of reducing conditions although the strength distribution (Weibull parameter, m) was relatively unaltered. Surface and volume dominated the fracture origins and the overall fracture was purely transgranular. The dual phas

S. Bandopadhyay

2008-08-30T23:59:59.000Z

457

Stability of CIGS Solar Cells and Component Materials Evaluated by a Step-Stress Accelerated Degradation Test Method: Preprint  

DOE Green Energy (OSTI)

A step-stress accelerated degradation testing (SSADT) method was employed for the first time to evaluate the stability of CuInGaSe2 (CIGS) solar cells and device component materials in four Al-framed test structures encapsulated with an edge sealant and three kinds of backsheet or moisture barrier film for moisture ingress control. The SSADT exposure used a 15oC and then a 15% relative humidity (RH) increment step, beginning from 40oC/40%RH (T/RH = 40/40) to 85oC/70%RH (85/70) as of the moment. The voluminous data acquired and processed as of total DH = 3956 h with 85/70 = 704 h produced the following results. The best CIGS solar cells in sample Set-1 with a moisture-permeable TPT backsheet showed essentially identical I-V degradation trend regardless of the Al-doped ZnO (AZO) layer thickness ranging from standard 0.12 ?m to 0.50 ?m on the cells. No clear 'stepwise' feature in the I-V parameter degradation curves corresponding to the SSADT T/RH/time profile was observed. Irregularity in I-V performance degradation pattern was observed with some cells showing early degradation at low T/RH < 55/55 and some showing large Voc, FF, and efficiency degradation due to increased series Rs (ohm-cm2) at T/RH ? 70/70. Results of (electrochemical) impedance spectroscopy (ECIS) analysis indicate degradation of the CIGS solar cells corresponded to increased series resistance Rs (ohm) and degraded parallel (minority carrier diffusion/recombination) resistance Rp, capacitance C, overall time constant Rp*C, and 'capacitor quality' factor (CPE-P), which were related to the cells? p-n junction properties. Heating at 85/70 appeared to benefit the CIGS solar cells as indicated by the largely recovered CPE-P factor. Device component materials, Mo on soda lime glass (Mo/SLG), bilayer ZnO (BZO), AlNi grid contact, and CdS/CIGS/Mo/SLG in test structures with TPT showed notable to significant degradation at T/RH ? 70/70. At T/RH = 85/70, substantial blistering of BZO layers on CIGS cell pieces was observed that was not seen on BZO/glass, and a CdS/CIGS sample displayed a small darkening and then flaking feature. Additionally, standard AlNi grid contact was less stable than thin Ni grid contact at T/RH ? 70/70. The edge sealant and moisture-blocking films were effective to block moisture ingress, as evidenced by the good stability of most CIGS solar cells and device components at T/RH = 85/70 for 704 h, and by preservation of the initial blue color on the RH indicator strips. The SSADT experiment is ongoing to be completed at T/RH = 85/85.

Pern, F. J.; Noufi, R.

2012-10-01T23:59:59.000Z

458

REPORTABLE RADIONUCLIDES IN DWPF SLUDGE BATCH 7A (MACROBATCH 8)  

Science Conference Proceedings (OSTI)

The Waste Acceptance Product Specifications (WAPS) 1.2 require that the waste producer 'shall report the curie inventory of radionuclides that have half-lives longer than 10 years and that are, or will be, present in concentrations greater than 0.05 percent of the total inventory for each waste type indexed to the years 2015 and 3115.' As part of the strategy to meet WAPS 1.2, the Defense Waste Processing Facility (DWPF) will report for each waste type all radionuclides that have half-lives longer than 10 years and contribute greater than 0.01 percent of the total curie inventory from the time of production through the 1100 year period from 2015 through 3115. The initial list of radionuclides to be reported is based on the design-basis glass identified in the Waste Form Compliance Plan (WCP) and Waste Form Qualification Report. However, it is required that the list be expanded if other radionuclides with half-lives greater than 10 years are identified that meet the 'greater than 0.01% of the curie inventory' criterion. Specification 1.6 of the WAPS, International Atomic Energy Agency Safeguards Reporting for High Level Waste (HLW), requires that the ratio by weights of the following uranium and plutonium isotopes be reported: U-233, U-234, U-235, U-236, and U-238; and Pu-238, Pu-239, Pu-240, Pu-241, and Pu-242. Therefore, the complete list of reportable radionuclides must also include these sets of U and Pu isotopes - and the U and Pu isotopic mass distributions must be identified. The DWPF receives HLW sludge slurry from Savannah River Site (SRS) Tank 40. For Sludge Batch 7a (SB7a), the waste in Tank 40 contained a blend of the heel from Sludge Batch 6 (SB6) and the Sludge Batch 7 (SB7) material transferred to Tank 40 from Tank 51. This sludge blend is also referred to as Macrobatch 8. Laboratory analyses of a Tank 40 sludge sample were performed to quantify the concentrations of pertinent radionuclides in the SB7a waste. Subsequently, radiological decay and in-growth were calculated over the time period from 2015 to 3115. This provided a basis for characterizing the radionuclide content of SB7a over time and for identifying the 'reportable radionuclides.' Details of the characterization methodology and the analytical results are the focus of this report. This work was performed at the request of the Waste Solidification Engineering Department of Savannah River Remediation, initiated via Technical Task Request (TTR) HLW-DWPF-TTR-2010-0031. A minor revision in the reporting requirements was requested via a subsequent email communication. The work was conducted in accordance with the protocols identified in Task Technical and Quality Assurance Plan SRNL-RP-2010-01218 and Analytical Study Plan SRNL-RP-2010-01219. All of the raw data related to this scope have been recorded in laboratory notebook SRNL-NB-2011-00061. The overall goal of this task was to characterize the radionuclide content of the SB7a waste sufficiently to meet the WAPS and DWPF reporting requirements. The specific objectives were: (1) Quantify the current concentrations of all radionuclides impacting (or potentially-impacting) the total curie content between calendar years 2011 and 3115. Also quantify the current concentrations of other radionuclides specifically requested in the TTR or required by the WAPS. (2) Calculate future concentrations of decayed and in-grown radionuclides impacting the total curie content between calendar years 2015 and 3115; (3) Identify as 'reportable' all radionuclides contributing {ge} 0.01% of the total curie content from 2015 to 3115 and having half-lives {ge} 10 years.

Reboul, S.; Diprete, D.; Click, D.; Bannochie, C.

2011-12-20T23:59:59.000Z

459

DEVELOPMENT OF TECHNOLOGIES AND ANALYTICAL CAPABILITIES FOR VISION 21 ENERGY PLANTS  

DOE Green Energy (OSTI)

The training of a new project team member was completed (Task 2.1). The Software Requirements Document was written (Task 2.3). It was determined that the CAPE-OPEN interfaces are sufficient for the communication between Fluent and V21 Controller (Task 2.4). The AspenPlus-Fluent prototype on allyl/triacetone alcohol production was further developed to assist the GUI and software design tasks. The prototype was also used to analyze the sensitivity of a process simulation result with respect to a parameter in a CFD model embedded in the process simulation. Thus the integration of process simulation and CFD provides additional process insights and enables the engineer to optimize overall process performance (e.g., product purity and yield) with respect to important CFD design and operation parameters (e.g., CSTR shaft speed). A top-level design of the V21 Controller was developed and discussed. A draft version of the Software Design Document was written (Task 2.5/2.6). A preliminary software development plan was outlined. At first the V21 Controller will be developed and tested in two parts--a part that communicates with Fluent and a part that communicates with Aspen Plus. Then the two parts will be combined and tested with the allyl/triacetone alcohol flow sheet simulation. Much progress was made in writing the code for the two parts (Task 2.7). A requirement for pre-configured models was identified and added to the software requirements document (Task 2.9). Alstom Power's INDVU code was ported to the PC platform and calibrated. Aspen Plus model of the RP&L unit was improved to reflect the latest information received on the unit. Thus the preparation for linking INDVU code with the Aspen Plus model of RP&L unit is complete (Task 2.14). A report describing Demo Case 1 was written and submitted to DOE for review and approval (Task 3.1). The first Advisory Board meeting was held at the Fluent Users Group Meeting on June 6th. At the Advisory Board meeting, the project was reviewed, a demonstration was made, and verbal feedback was received. Meeting minutes have been issued (Task 5.0). Global-CAPE-OPEN organization was contacted for obtaining draft specifications in CORBA that are needed for writing the interfaces between V21 Controller and Fluent. Efforts are underway to establish collaboration with Norsk Hydro, who is leading a Global CAPE-OPEN project on linking CFD and process simulation models. Because of the similarity between that project and the present project, the two project teams can learn much from each other (Task 7.0).

Madhava Syamlal, Ph.D.

2001-07-10T23:59:59.000Z

460

Prioritizing and scheduling Portsmouth Gaseous Diffusion Plant safeguards upgrades. Final report  

Science Conference Proceedings (OSTI)

As part of the Site Safeguards and Security Plan (SSSP), facilities are required to develop a Resource Plan (RP). The Resource Plan provides documentation and justification for the facility`s planned upgrades, including the schedule, priority, and cost estimates for the safeguards and security upgrades. Portsmouth Gaseous Diffusion Plant (PORTS) management has identified and obtained funding approval for a number of safeguards and security upgrades, including line-item construction projects. These upgrade projects were selected to address a variety of concerns identified in the PORTS vulnerability assessments and other reviews performed in support of the SSSP process. However, budgeting and scheduling constraints do not make it possible to simultaneously begin implementation of all of the upgrade projects. A formal methodology and analysis are needed to explicitly address the trade-offs between competing safeguards objectives, and to prioritize and schedule the upgrade projects to ensure that the maximum benefit can be realized in the shortest possible time frame. The purpose of this report is to describe the methodology developed to support these upgrade project scheduling decisions. The report also presents the results obtained from applying the methodology to a set of the upgrade projects selected by PORTS S&S management. Data for the analysis are based on discussions with personnel familiar with the PORTS safeguards and security needs, the requirements for implementing these upgrades, and upgrade funding limitations. The analysis results presented here assume continued highly enriched uranium (HEU) operations at PORTS. However, the methodology developed is readily adaptable for the evaluation of other operational scenarios and other resource allocation issues relevant to PORTS.

Edmunds, T.; Saleh, R.; Zevanove, S.

1992-02-01T23:59:59.000Z

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461

Hydrodynamic Models of Type I X-Ray Bursts: Metallicity Effects  

E-Print Network (OSTI)

Type I X-ray bursts are thermonuclear stellar explosions driven by charged-particle reactions. In the regime for combined H/He-ignition, the main nuclear flow is dominated by the rp-process (rapid proton-captures and beta+ decays), the 3 alpha-reaction, and the alpha-p-process (a suite of (alpha,p) and (p,gamma) reactions). The main flow is expected to proceed away from the valley of stability, eventually reaching the proton drip-line beyond A = 38. Detailed analysis of the relevant reactions along the main path has only been scarcely addressed, mainly in the context of parameterized one-zone models. In this paper, we present a detailed study of the nucleosynthesis and nuclear processes powering type I X-ray bursts. The reported 11 bursts have been computed by means of a spherically symmetric (1D), Lagrangian, hydrodynamic code, linked to a nuclear reaction network that contains 325 isotopes (from 1H to 107Te), and 1392 nuclear processes. These evolutionary sequences, followed from the onset of accretion up to the explosion and expansion stages, have been performed for 2 different metallicities to explore the dependence between the extension of the main nuclear flow and the initial metal content. We carefully analyze the dominant reactions and the products of nucleosynthesis, together with the the physical parameters that determine the light curve (including recurrence times, ratios between persistent and burst luminosities, or the extent of the envelope expansion). Results are in qualitative agreement with the observed properties of some well-studied bursting sources. Leakage from the predicted SbSnTe-cycle cannot be discarded in some of our models. Production of 12C (and implications for the mechanism that powers superbursts), light p-nuclei, and the amount of H left over after the bursting episodes will also be discussed.

Jordi Jose; Fermin Moreno; Anuj Parikh; Christian Iliadis

2010-05-26T23:59:59.000Z

462

Application of 2D VSP Imaging Technology to the Targeting of Exploration  

Open Energy Info (EERE)

VSP Imaging Technology to the Targeting of Exploration VSP Imaging Technology to the Targeting of Exploration and Production Wells in a Basin and Range Geothermal System Humboldt House-Rye Patch Geothermal Area Geothermal Project Jump to: navigation, search Last modified on July 22, 2011. Project Title Application of 2D VSP Imaging Technology to the Targeting of Exploration and Production Wells in a Basin and Range Geothermal System Humboldt House-Rye Patch Geothermal Area Project Type / Topic 1 Recovery Act: Geothermal Technologies Program Project Type / Topic 2 Validation of Innovative Exploration Technologies Project Description Phase I will consist of the acquisition, processing and interpretation of two 2-dimensional vertical seismic profiles (VSPs) at strategic positions crossing the range front fault system in the Humboldt House-Rye Patch (HH-RP) geothermal resource area. APEX-HiPoint Reservoir Imaging, Project team partner, will use its borehole seismic technology deploying up to 240 multicomponent phones on a fiber optic wireline system coupled to a high-volume data acquisition system. A vibroseis source will be recorded along the 2D profiles with offsets up to 10,000 feet on either side of the receiver wells, creating a wide horizontal aperture. Using dynamic borehole cooling, the APEX receivers will be deployed in an extended vertical array above and below the interface (and large velocity contrast) between Tertiary valley fill sediments and Triassic and older reservoir rocks, significantly increasing vertical aperture, multiplicity, frequency and signal quality. Optim, Project Team partner, will use its patented nonlinear optimization technique on both borehole and surface data to obtain high resolution velocity models down to target depths, also a "first". HiPoint's patented, time-domain processing techniques will be employed to provide accurate, high-resolution reflection images in a fraction of previous compute times.

463

S Se  

NLE Websites -- All DOE Office Websites (Extended Search)

Se Se er rp pe en nt ti in ne e S St ty yl le e C Co oi il l W Wi in nd di in ng gs s f fo or r B BE EP PC C- -I II I I IR R M Ma ag gn ne et t P Pr ro od du uc ct ti io on n V Viid de eo oc co on nffe er re en nc ce e B Be ettw we ee en n IIH HE EP P a an nd d B BN NL L S Sc ch he ed du ulle ed d ffo or r M Ma ar rc ch h 3 3,, 2 20 00 04 4 o on n B BE EP PC C- -IIII S SC C M Ma ag gn ne ett P Pr ro od du uc cttiio on n.. Presented by Brett Parker/BNL - SMD First SCQ Production Coil Winding 7 0 0 Z (mm) 300 200 100 θ (deg.) 5 0 0 Z (mm) θ (deg.) O Or ri ig gi in na al l D Do ou ub bl le e- -L La ay ye er r B BE EP PC C- -I II I C Co oi il l W Wi in nd di in ng g P Pa at tt te er rn ns s f fo or r S SC CB B a an nd d S SC CQ Q. . The plan had been to wind one coil pole and then stop winding to fill in gaps with G10 before adding new substrate and then continue winding the same pole in the second layer. This was maybe not so bad for SCB where we would have had to stop/start twice but for the four double-layer SCQ we would have had sixteen stop/starts

464

DEVELOPMENT OF TECHNOLOGIES AND ANALYTICAL CAPABILITIES FOR VISION 21 ENERGY PLANTS  

DOE Green Energy (OSTI)

DOE Vision 21 project requirements for the support of Global CAPE-OPEN Reaction Kinetics interfaces in Aspen Plus 12 was written (Task 2.4). The software design document was written and posted on the project web site. Intergraph started work on a proof of concept demo of the physical domain software (Task 2.6). The COM-side (Aspen Plus) and CORBA-side (Fluent) pieces of the Vision 21 controller code were written and independently verified. The two pieces of the code were then combined. Debugging of the combined code is underway (Task 2.7). Papers on fuel cell processes were read in preparation for developing an example based on a fuel cell process (Task 2.8). The INDVU code has been used to replace the boiler component in the Aspen Plus flowsheet of the RP&L power plant. The INDVU code receives information from Aspen Plus and iterates on the split backpass LTSH bypass and excess air quantities until the stipulated superheat outlet temperature is satisfied. The combined INDVU-Aspen Plus model has been run for several load conditions (Task 2.14). Work on identifying a second demonstration case involving an advanced power cycle has been started (Task 3.2). Plans for the second Advisory Board meeting in November were made (Task 5.0). Intergraph subcontract was signed and work on a physical domain software demo was started. A second teleconference with Norsk Hydro was conducted to discuss Global CAPE-OPEN standards and issues related to COM-CORBA Bridge (Task 7.0).

Madhava Syamlal, Ph.D.

2001-10-20T23:59:59.000Z

465

Radioactive releases at the Savannah River Site, 1954--1988  

Science Conference Proceedings (OSTI)

Radioactive Releases at the Savannah River Site, 1954--1988 (WSRC-RP-89-737) is the continuation of a series of reports, previously titled Releases of Radioactivity at the Savannah River Plant (DPSU-1-YR-25). The series reflects the use of air and liquid effluent sample analyses in determining the amount of radioactivity released from Savannah River Site (SRS) operations. The identification and characterization of these source terms since plant startup in 1954 have aided Site personnel in confining and limiting the amount of radioactivity released to the environment from SRS facilities. Data contained in this report are used for a variety of purposes, including the calculation of offsite dose estimates and aiding special environmental studies. This document is an effluent/source term report. The report is divided into four summary sections. Summary A details volumes of air and water released from emission sources since plant startup. Summary B lists annual radioactive release data from these emission sources, grouped by nuclide and area. Summary C provides yearly totals of radioactive releases by radionuclide, under the headings Atmospheric,'' Liquid to streams,'' or Liquid to Seepage Basins'' accordingly. Monthly radioactive releases from each emission source from 1986 to 1988 are found in Summary D. Where appropriate, headings in the summary tables have been changed to clarify and simplify emission data (see Appendix B). Additionally, any new discharge points, such as the liquid discharge from the Effluent Treatment Facility (ETF), are included in this report. A listing of 1988 source term and onsite discharge designations is provided in Appendix C. 36 refs.

Hetrick, C.S.; Martin, D.K.

1988-01-01T23:59:59.000Z

466

DEVELOPMENT OF TECHNOLOGIES AND ANALYTICAL CAPABILITIES FOR VISION 21 ENERGY PLANTS  

SciTech Connect

A software design review meeting was conducted (Task 2.0). A CFD Viewer was developed, to allow the process analyst to view CFD results from the process simulator (Task 2.14). Work on developing a CO wrapper for the INDVU code was continued (Task 2.15). The model-edit GUI was modified to allow the user to specify a solution strategy. Enhancements were made to the solution strategy implementation (Task 2.16). Testing of the integrated software was continued and several bug fixes and enhancements were made: ability to expose CFD parameters to the process analyst and support for velocity and pressure inlet boundary conditions (Task 2.21). Work on preparing the release version progressed: Version 0.3 of V21 Controller was released, a global configuration dialog was implemented, and a code review process was initiated (Task 2.24). The calibration of the tube bank CFD model for the RP&L case was completed. While integrating the tube bank CFD model into the flow sheet model, several development requirements were identified and communicated to the developers. The requirements of porting V21 Controller and Configuration Wizard to FLUENT 6.1, turning off the transfer of temperature dependent properties, exposing CFD parameters in Aspen Plus and supporting velocity boundary conditions have been implemented (Task 4.1). An initial grid for the HRSG component has been prepared (Task 4.2). A web-based advisory board meeting was conducted on December 18, 2003 (Task 5.0). Project personnel attended and gave presentations at the Aspen World Conference, October 28-30, 2002; AIChE Annual Meeting, November 8, 2002; and the Vision 21 Simulation meeting at Iowa State University, November 19-20, 2002 (Task 7.0).

Madhava Syamlal, Ph.D.

2002-12-31T23:59:59.000Z

467

Analysis of drilling fluid rheology and tool joint effect to reduce errors in hydraulics calculations  

E-Print Network (OSTI)

This study presents a simplified and accurate procedure for selecting the rheological model which best fits the rheological properties of a given non- Newtonian fluid and introduces five new approaches to correct for tool joint losses from expansion and contraction when hydraulics is calculated. The new approaches are enlargement and contraction (E&C), equivalent diameter (ED), two different (2IDs), enlargement and contraction plus equivalent diameter (E&C+ED), and enlargement and contraction plus two different IDs (E&C+2IDs). In addition to the Newtonian model, seven major non-Newtonian rheological models (Bingham plastic, Power law, API, Herschel-Bulkley, Unified, Robertson and Stiff, and Casson) provide alternatives for selecting the model that most accurately represents the shear-stress/shear-rate relationship for a given non- Newtonian fluid. The project assumes that the model which gives the lowest absolute average percent error (EAAP) between the measured and calculated shear stresses is the best one for a given non-Newtonian fluid. The results are of great importance in achieving correct results for pressure drop and hydraulics calculations and the results are that the API rheological model (RP 13D) provides, in general, the best prediction of rheological behavior for the mud samples considered (EAAP=1.51), followed by the Herschel-Bulkley, Robertson and Stiff, and Unified models. Results also show that corrections with E&C+2IDs and API hydraulics calculation give a good approximation to measured pump pressure with 9% of difference between measured and calculated data.

Viloria Ochoa, Marilyn

2006-08-01T23:59:59.000Z

468

Identification of Novel Positive-Strand RNA Viruses by Metagenomic Analysis of Archaea-Dominated Yellowstone Hot Springs  

DOE Green Energy (OSTI)

There are no known RNA viruses that infect Archaea. Filling this gap in our knowledge of viruses will enhance our understanding of the relationships between RNA viruses from the three domains of cellular life and, in particular, could shed light on the origin of the enormous diversity of RNA viruses infecting eukaryotes. We describe here the identification of novel RNA viral genome segments from high-temperature acidic hot springs in Yellowstone National Park in the United States. These hot springs harbor low-complexity cellular communities dominated by several species of hyperthermophilic Archaea. A viral metagenomics approach was taken to assemble segments of these RNA virus genomes from viral populations isolated directly from hot spring samples. Analysis of these RNA metagenomes demonstrated unique gene content that is not generally related to known RNA viruses of Bacteria and Eukarya. However, genes for RNA-dependent RNA polymerase (RdRp), a hallmark of positive-strand RNA viruses, were identified in two contigs. One of these contigs is approximately 5,600 nucleotides in length and encodes a polyprotein that also contains a region homologous to the capsid protein of nodaviruses, tetraviruses, and birnaviruses. Phylogenetic analyses of the RdRps encoded in these contigs indicate that the putative archaeal viruses form a unique group that is distinct from the RdRps of RNA viruses of Eukarya and Bacteria. Collectively, our findings suggest the existence of novel positive-strand RNA viruses that probably replicate in hyperthermophilic archaeal hosts and are highly divergent from RNA viruses that infect eukaryotes and even more distant from known bacterial RNA viruses. These positive-strand RNA viruses might be direct ancestors of RNA viruses of eukaryotes.

Benjamin Bolduc; Daniel P. Shaughnessy; Yuri I. Wolf; Eugene V. Koonin; Francisco F. Roberto; Mark Young

2012-05-01T23:59:59.000Z

469

U.S. Timber Production, Trade, Consumption, and Price Statistics  

E-Print Network (OSTI)

This report is part of an annual series that presents current and historical information on the production, trade, consumption, and prices of timber products in the United States. The report focuses on national statistics, but includes some data for individual States and regions and for Canada. The data were collected from industry trade associations and government agencies. They are intended for use by forest land managers, forest industries, trade associations, forestry schools, renewable resource organizations, libraries, organizations, individuals in the major timber producing and consuming countries of the world, and the general public. A major use of the data presented here is tracking technological change over time. One of the major technology shifts occurring in the wood-using industry is the substitution of oriented strandboard (OSB) for plywood in the structural panel sector, as well as a shift in plywood production from the west to the south United States. Some data show these shifts. United States production of structural panels totaled 29.4 billion ft in 1999. Production of OSB increased from less than 3 billion ft in 1985 to 11.6 billion ft in 1999. Plywood production was 20.1 billion ft in 1985 before falling to 17.8 billion ft in 1999. The decline in plywood production reflects the continued increase in the OSB share of the traditional plywood market Keywords: production, consumption, import, export April 2001 Howard, James. L. 2001. U.S. timber production, trade consumption, and price statistics 1965 to 1999. Res. Pap. FPL-RP-595. Madison, WI: U.S. Department of Agriculture, Forest Service, Forest Products Laboratory. 90 p. A limited number of free copies of this publication are available to the public from the Forest Products Laboratory, One Gifford Pi...

James Howard United; United States; Forest Service; Price Statistics; James L. Howard

2001-01-01T23:59:59.000Z

470

Pilot program on patient dosimetry in pediatric interventional cardiology in Chile  

Science Conference Proceedings (OSTI)

Purpose: The aim of this study was to present the results of a pilot program on patient dosimetry carried out in Chile during the last 5 yr, using a biplane x-ray angiography system settled for pediatrics. This research was conducted in Latin America under the auspices of the International Atomic Energy Agency (IAEA) supporting programs on radiological protection (RP) of patients. Methods: Patient age, gender, weight, height, number of cine series, total number of cine frames, fluoroscopy time, and two dosimetric quantities [air kerma-area product (P{sub ka}) and cumulative dose (CD) at the patient entrance reference point] were recorded for each procedure. Results: The study includes 544 patients grouped into four age groups. The distributions by age group were 150 for <1 yr; 203 for 1 to <5 yr; 97 for 5 to <10 yr; and 94 for 10 to <16 yr. Median values of P{sub ka} and CD for the four age groups were 0.94, 1.46, 2.13, and 5.03 Gy cm{sup 2} and 23.9, 26.8, 33.5, and 51.6 mGy, respectively. No significant statistical differences were found between diagnostic and therapeutic procedures. A moderate correlation (r = 0.64) was seen between P{sub ka} and patient weight. Conclusions: The dose values reported in this paper were lower than those published in the previous work for the same age groups as a result of the optimization actions carried out by cardiologists and medical physicists with the support of the IAEA. Methodology and results will be used as a starting point for a wider survey in Chile and Latin America with the goal to obtain regional diagnostic reference levels as recently recommended by the International Commission on Radiological Protection for interventional procedures.

Ubeda, Carlos; Vano, Eliseo; Miranda, Patricia; Leyton, Fernando [Clinical Sciences Department, Radiological Sciences Center, Health Sciences Faculty and CHIDE, Tarapaca University, Arica (Chile); Radiology Department, Complutense University and San Carlos Hospital, 28040 Madrid (Spain); Hemodynamic Department, Cardiovascular Service, Luis Calvo Mackenna Hospital, Santiago (Chile); Institute of Public Health of Chile, Marathon 1000, Nunoa, Santiago, Chile and Faculty of Medicine, Diego Portales University, Santiago (Chile)

2012-05-15T23:59:59.000Z

471

LIFAC Demonstration at Richmond Power and Light Whitewater Valley Unit No. 2 Volume II: Project Performance and Economics  

SciTech Connect

The C1ean Coal Technology (CCT) Program has been recognized in the National Energy Strategy as a major initiative whereby coal will be able to reach its full potential as a source of energy for the nation and the international marketplace. Attainment of this goal depends upon the development of highly efficient, environmentally sound, competitive coal utilization technologies responsive to diverse energy markets and varied consumer needs. The CCT Program is an effort jointly funded by government and industry whereby the most promising of the advanced coal-based technologies are being moved into the marketplace through demonstration. The CCT Program is being implemented through a total of five competitive solicitations. LIFAC North America, a joint venture partnership of ICF Kaiser Engineers, Inc., and Tampella Power Corporation, is currently demonstrating the LIFAC flue gas desulfurization technology developed by Tampella Power. This technology provides sulfur dioxide emission control for power plants, especially existing facilities with tight space limitations. Sulfur dioxide emissions are expected to be reduced by up to 85% by using limestone as a sorbent. The LIFAC technology is being demonstrated at Whitewater Valley Unit No. 2, a 60-MW coal-fired power plant owned and operated by Richmond Power and Light (RP&L) and located in Richmond, Indiana. The Whitewater plant consumes high-sulfur coals, with sulfur contents ranging from 2.0-2.9 $ZO. The project, co-funded by LIFAC North America and DOE, is being conducted with the participation of Richmond Power and Light, the State of Indiana, the Electric Power Research Institute (EPRI), and the Black Beauty Coal Company. The project has a total cost of $21.4 million and a duration of 48 months from the preliminary design phase through the testing program.

None

1998-04-01T23:59:59.000Z

472

Conductor fatigue-life research. Final report  

Science Conference Proceedings (OSTI)

This is the final report of Research Project RP 1278-1 sponsored by the Electric Power Research Institute and carried out at the Civil Engineering Department of Auburn University (Auburn, Alabama). The objective of this study was to evaluate the effects of reducing vibration amplitudes of ACSR conductors which had been minimally damaged by aeolian vibration. The aeolian vibration was simulated by mechanical means in a controlled laboratory situation and the reduction in vibration amplitudes was a simulation of the addition of amplitude limiting devices (dampers). Conductors were vibrated at high amplitudes until a predetermined number of strand breaks occurred, after which the vibration was continued at reduced amplitudes. Three different ACSB conductors were tested: 795 KCM 26/7, 795 KCM 45/7, and 397.5 KCM 26/7. These conductors were chosen to establish the effects of conductor size and stranding on the amplitude reduction tests. Two different amplitude reductions were used to establish a threshold value for a maximum reduced amplitude. Previous preliminary research by others indicated that amplitude reductions extended the working life of conductors. This research expanded the amplitude reduction values and conductor sizes and strandings tested. For each set of parameters, four duplicative tests were performed to give statistical credence to the data. The results of the investigation indicated that amplitude reductions arrested fatigue strand breakage in each case. Electric utilities can utilize the results of this EPRI project in assessing the fatigue life of minimally damaged transmisson lines and in evaluating techniques for mitigating fatigue damage.

Ramey, G.E.

1981-07-01T23:59:59.000Z

473

On the temperature profile of radiatively efficient geometrically thin disks in black hole binaries with the ASCA GIS  

E-Print Network (OSTI)

X-ray spectra of black hole binaries(BHBs) in the high/soft state were studied comprehensively by using ASCA GIS data, and partially RXTE PCA data. A mathematical disk model was applied to several BHBs to see if the observed accretion disk temperature profile was consistent with that expected from the standard accretion disk model. This model is called p-free disk, and assumes that the spectrum is composed of multi-temperature blackbody emission of which the local temperature T(r) at radius r is given by T(r) ~ r^-p with p being a positive free parameter. The standard disk roughly requires p~3/4, while a small deviation is expected depending on the inner boundary conditions, general relativistic effects and disk vertical structures.Our sample objects included LMC X-1, LMC X-3, XTE J2012+381, and GRO J1655-40. During the ASCA observations, these BHBs showed characteristics of the standard high/soft state. Under the standard modeling of high-state black hole binaries, the sources show Tin=0.76-1.17keV, the disk fraction to the total 0.7-10keV flux of 54-98%, and Nh=(0.7--12)E21/cm^2. The best-fit p-values were found in 0.6-0.8, and the standard value of p=3/4 was accepted for all the sources.The obtained p-values are also compared with those expected for the standard accretion disk in the Schwarzschild metric, and they were consistent with those expected from the standard accretion disk.

Aya Kubota; Ken Ebisawa; Kazuo Makishima; Kazuhiro Nakazawa

2005-05-17T23:59:59.000Z

474

Approved by  

E-Print Network (OSTI)

Reliability studies of systems have been an important area of research within electrical engineering for over a quarter of a century. In this thesis, the reliability analysis of the Supervisory Control And Data Acquisition (SCADA) systems used in offshore petroleum facilities was examined. This thesis presents fault trees for the platform production facilities, subsea control systems, a typical SCADA system, and the human induced fault tree. Software reliability was also studied. The fault trees were developed based on a safety flow chart and Process and Instrumentation Diagrams (P&ID). This work was conducted as a subcontract to the United States Department of the Interior, Mineral Management Service, Technology Assessment & Research Program, Program SOL 1435-01-99-RP-3995 (project no 356) to the University of Missouri-Rolla. Based on the fault tree diagrams and fault rates, the reliability of the SCADA system used in the offshore facilities was assessed. The failure availability of the SCADA system used in offshore platforms was also found. iv ACKNOWLEDGMENTS The author wishes to thank Dr. Kelvin. T. Erickson for his guidance and assistance not only in the preparation of this work, but also his valuable contributions in M.S. studies. The author sincerely appreciates the help and encouragement received from Dr. Eldon K. Stanek for the preparation and completion of this project. He was not only my supervisor, but also he was like a father throughout my stay at University of Missouri-Rolla. The author is thankful to Dr. Shari Dunn-Norman for her help in understanding

Egemen Kemal Cetinkaya; Kelvin T. Erickson; Egemen Kemal Cetinkaya

2001-01-01T23:59:59.000Z

475

Charge and Spin Transport in Superconducting Weak Links  

E-Print Network (OSTI)

Abstract. The coherent mixing of the current states in the superconducting weak link subject to a Josephson phase difference ? and subject to an external transport current in the banks is one of the aims of this work. At ? = ? the nonlocal mixing of current states produces two vortices close to the point-contact between superconducting bulks. The effect of point-contact reflection in an impenetrable interface and effect of temperature on the vortices have been studied. It is obtained that increasing the reflection of the point-contact destroys the vortices while increasing the temperature restore these vortices. The vortex state is a new version of the interference between the macroscopic states and quantum tunnelling. Also, the weak link between unitary triplet superconductors which have f?wave and p + h?wave pairing symmetry has been studied from the spin and charge current-phase relation point of view. The main result in the second part of this thesis, is the polarization of the spin transport when a junction between triplet superconductors is used. It is observed that the spin current is the result of the misorientation between the gap vectors of two supercondcutors. In addition, the weak link between two bipolar nonunitary triplet superconductors is studied mathematically. The current-phase relations obtained in third part of this thesis are totally different from the junctions between the unitary spin-triplet superconductors and between the spin-singlet superconductors. The current phase diagrams which have been obtained in this work can be used to distinguish the symmetry of the order parameter in the crystals. PACS numbers: 74.50.+r, 74.20.Rp, 72.25.-b, 74.70.Pq, 74.70.TxCharge and Spin Transport in Superconducting Weak Links 2 1.

Gholamreza Rashedi

2005-01-01T23:59:59.000Z

476

Revisions to the hydrogen gas generation computer model  

DOE Green Energy (OSTI)

Waste Management Technology has requested SRTC to maintain and extend a previously developed computer model, TRUGAS, which calculates hydrogen gas concentrations within the transuranic (TRU) waste drums. TRUGAS was written by Frank G. Smith using the BASIC language and is described in the report A Computer Model of gas Generation and Transport within TRU Waste Drums (DP- 1754). The computer model has been partially validated by yielding results similar to experimental data collected at SRL and LANL over a wide range of conditions. The model was created to provide the capability of predicting conditions that could potentially lead to the formation of flammable gas concentrations within drums, and to assess proposed drum venting methods. The model has served as a tool in determining how gas concentrations are affected by parameters such as filter vent sizes, waste composition, gas generation values, the number and types of enclosures, water instrusion into the drum, and curie loading. The success of the TRUGAS model has prompted an interest in the program`s maintenance and enhancement. Experimental data continues to be collected at various sites on such parameters as permeability values, packaging arrangements, filter designs, and waste contents. Information provided by this data is used to improve the accuracy of the model`s predictions. Also, several modifications to the model have been made to enlarge the scope of problems which can be analyzed. For instance, the model has been used to calculate hydrogen concentrations inside steel cabinets containing retired glove boxes (WSRC-RP-89-762). The revised TRUGAS computer model, H2GAS, is described in this report. This report summarizes all modifications made to the TRUGAS computer model and provides documentation useful for making future updates to H2GAS.

Jerrell, J.W.

1992-08-31T23:59:59.000Z

477

Revisions to the hydrogen gas generation computer model  

DOE Green Energy (OSTI)

Waste Management Technology has requested SRTC to maintain and extend a previously developed computer model, TRUGAS, which calculates hydrogen gas concentrations within the transuranic (TRU) waste drums. TRUGAS was written by Frank G. Smith using the BASIC language and is described in the report A Computer Model of gas Generation and Transport within TRU Waste Drums (DP- 1754). The computer model has been partially validated by yielding results similar to experimental data collected at SRL and LANL over a wide range of conditions. The model was created to provide the capability of predicting conditions that could potentially lead to the formation of flammable gas concentrations within drums, and to assess proposed drum venting methods. The model has served as a tool in determining how gas concentrations are affected by parameters such as filter vent sizes, waste composition, gas generation values, the number and types of enclosures, water instrusion into the drum, and curie loading. The success of the TRUGAS model has prompted an interest in the program's maintenance and enhancement. Experimental data continues to be collected at various sites on such parameters as permeability values, packaging arrangements, filter designs, and waste contents. Information provided by this data is used to improve the accuracy of the model's predictions. Also, several modifications to the model have been made to enlarge the scope of problems which can be analyzed. For instance, the model has been used to calculate hydrogen concentrations inside steel cabinets containing retired glove boxes (WSRC-RP-89-762). The revised TRUGAS computer model, H2GAS, is described in this report. This report summarizes all modifications made to the TRUGAS computer model and provides documentation useful for making future updates to H2GAS.

Jerrell, J.W.

1992-08-31T23:59:59.000Z

478

Catalytic properties and mechanism studies of the PepQ prolidase from Escherichia coli  

E-Print Network (OSTI)

The PepQ prolidase from Escherichia coli catalyzes the hydrolysis of dipeptide substrates with proline residues at the C-terminus. The PepQ gene has been cloned, overexpressed and the enzyme purified to homogeneity. The kcat and kcat/Km values for the hydrolysis of Met-Pro are 109 s-1 and 8.4 x 105 M-1 s-1, respectively. The enzyme also catalyzes the stereoselective hydrolysis of organophosphate triesters and organophosphonate diesters. A series of 16 organophosphate triesters with a p-nitrophenyl leaving group was assessed as substrates for this enzyme. The SP-enantiomer of methyl phenyl p-nitrophenyl phosphate was hydrolyzed with a kcat of 36 min-1 and a kcat/Km of 710 M-1 s-1. The corresponding RP-enantiomer was more slowly hydrolyzed with a kcat of 0.4 min-1 and a kcat/Km of 11 M-1 s-1. The PepQ prolidase can be utilized for the kinetic resolution of racemic phosphate esters. The PepQ prolidase was shown to hydrolyze the p-nitrophenyl analogs of the nerve agents GB (sarin), GD (soman), GF, and VX. The pH-rate profiles for the wild-type E. coli prolidase using proline dipeptides as substrates were obtained. The roles of H346, H228, and E384 in the enzyme catalytic mechanism were also investigated by obtaining the pH-rate profiles for the mutants H346N, H228N, and E384Q. In an effort to clarify the mechanistic role of the interaction of the ?±-amino group of Xaa-Pro with metal at the enzyme active site, comparisons of the hydrolytic activity for Ala-Pro and 1-(1-oxopropyl)-L-proline, in which a hydrogen replaces the ?±-amino group of Ala-Pro, were performed.

Park, Min Sun

2005-08-01T23:59:59.000Z

479

Experimental Investigation of Fuel-Reactivity Controlled Compression Ignition (RCCI) Combustion Mode in a Multi-Cylinder, Light-Duty Diesel Engine  

DOE Green Energy (OSTI)

An experimental study was performed to provide the combustion and emission characteristics resulting from fuel-reactivity controlled compression ignition (RCCI) combustion mode utilizing dual-fuel approach in a light-duty, multi-cylinder diesel engine. In-cylinder fuel blending using port fuel injection of gasoline before intake valve opening (IVO) and early-cycle, direct injection of diesel fuel was used as the charge preparation and fuel blending strategy. In order to achieve the desired auto-ignition quality through the stratification of the fuel-air equivalence ratio ( ), blends of commercially available gasoline and diesel fuel were used. Engine experiments were performed at an engine speed of 2300rpm and an engine load of 4.3bar brake mean effective pressure (BMEP). It was found that significant reduction in both nitrogen oxide (NOx) and particulate matter (PM) was realized successfully through the RCCI combustion mode even without applying exhaust gas recirculation (EGR). However, high carbon monoxide (CO) and hydrocarbon (HC) emissions were observed. The low combustion gas temperature during the expansion and exhaust processes seemed to be the dominant source of high CO emissions in the RCCI combustion mode. The high HC emissions during the RCCI combustion mode could be due to the increased combustion quenching layer thickness as well as the -stratification at the periphery of the combustion chamber. The slightly higher brake thermal efficiency (BTE) of the RCCI combustion mode was observed than the other combustion modes, such as the conventional diesel combustion (CDC) mode, and single-fuel, premixed charge compression ignition (PCCI) combustion mode. The parametric study of the RCCI combustion mode revealed that the combustion phasing and/or the peak cylinder pressure rise rate of the RCCI combustion mode could be controlled by several physical parameters premixed ratio (rp), intake swirl intensity, and start of injection (SOI) timing of directly injected fuel unlike other low temperature combustion (LTC) strategies.

Cho, Kukwon [ORNL; Curran, Scott [ORNL; Prikhodko, Vitaly Y [ORNL; Sluder, Scott [ORNL; Parks, II, James E [ORNL; Wagner, Robert M [ORNL

2011-01-01T23:59:59.000Z

480

Operators, Correlators and Free Fermions for SO(N) and Sp(N)  

E-Print Network (OSTI)

Using the recently constructed basis for local operators in free SO(N) gauge theory we derive an exact formula for the correlation functions of multi trace operators. This formula is used to obtain a simpler form and a simple product rule for the operators in the SO(N) basis. The coefficients of the product rule are the Littlewood-Richardson numbers which determine the corresponding product rule in free U(N) gauge theory. SO(N) gauge theory is dual to a non-oriented string theory on the AdS_5xRP^5 geometry. To explore the physics of this string theory we consider the limit of the gauge theory that, for the U(N) gauge theory, is dual to the pp-wave limit of AdS_5xS^5. Non-planar unoriented ribbon diagrams do not survive this limit. We give arguments that the number of operators in our basis matches counting using the exact free field partition function of free SO(N) gauge theory. We connect the basis we have constructed to free fermions, which has a natural interpretation in terms of a class of 1/2-BPS bubbling geometries, which arise as orientifolds of type IIB string theory. Finally, we obtain a complete generalization of these results to Sp(N) gauge theory by proving that the finite N physics of SO(N) and Sp(N) gauge theory are related by exchanging symmetrizations and antisymmetrizations and replacing N by -N.

Pawel Caputa; Robert de Mello Koch; Pablo Diaz

2013-03-28T23:59:59.000Z

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481

Interim consensus guidelines on fossil plant cycle chemistry. Final report  

Science Conference Proceedings (OSTI)

US utilities have been faced with a multitude of water and steam control limits disseminated by various groups and manufacturers. These have provided disparate goals for plant personnel and management in determining the operating limits for their plants. EPRI authorized the preparation of guidelines on fossil plant cycle chemistry as part of a research program, RP2712, with the goal to reduce forced outages and efficiency losses related to water chemistry, corrosion, and deposition. This report is a unified, specific, and comprehensive document that provides the guidance needed for effective and economical control of corrosion and deposition. Implementation of these Guidelines will help reduce forced outages caused by corrosion-induced failures and thereby increase unit availability. The Guidelines provide a set of target values and action levels for critical sample points throughout the water and steam cycle for drum boilers with phosphate treatment; for drum boilers with all-volatile treatment; and for once-through boilers. They are applicable to baseload and to cycling and peaking operation. Corrective actions to be taken when the Guidelines are exceeded are also discussed. More general guidelines are given on management responsibilities, layup, representative sampling, analytical methods, continuous instrumentation, data collection and management, and other considerations. The Guidelines and the results of the other phases of the EPRI Research Project 2712 should bring significant benefits to US utilities at a moderate cost. Modification of portions of the Guidelines to reflect actual, plant-specific design characteristics and local operating experience is recommended when appropriately justified. 118 refs., 88 figs., 24 tabs.

Aschoff, A.F.; Lee, Y.H.; Sopocy, D.M.; Jonas, O.

1986-06-01T23:59:59.000Z

482

Investigations of the Biological Roles of Substituted Cyclohexadienes  

E-Print Network (OSTI)

In recent years there have been two cycloterpenals, molecules consisting of a cyclohexadienal core, isolated from nature. Cyclocitral, the condensation product of citral, has been isolated from the North Sea bryozoans Flustra foliacea. In the human eyes, cycloretinal has been isolated and is a toxic by product of the vision cycle. This retinal dimer is believed to contribute to age related macular degeneration, the leading cause of blindness in the elderly. In 1992, it was discovered that if [beta]-ionylideneacetaldehyde was incubated with beta-lactoglobulin ([beta]-LG), the principal whey protein in dairy milk, that it would mediate the formation of cyclo-[beta]-ional. No follow up studies were performed on this protein mediated reaction or what biological activities these cycloterpenals may possess. This dissertation investigates the biological roles of substituted cyclohexadienes including cycloterpenals and cyclohexadiene enaminonitriles. To mimic the protein mediated reaction, we developed a synthetic procedure to produce a wide array of cycloterpenal by utilizing L-proline. Over 100 cycloterpenals were synthesized and screened for their biological activities against an array of cell based screens. The phenotypic effects of these cycloterpenals were screened against a PC12 assay where dramatic effects were observed on neurite outgrowth. During the synthesis of starting materials for the production of our cycloterpenal library, it was discovered that if excess base was added to the Horner-Wadsworth-Emmons reaction between a methyl-ketone and diethyl-(cyanomethyl)-phosphonate, conversion of the [alpha]-[beta]-unsaturated nitrile into an enaminonitrile was observed. This new synthetic procedure was optimized to generate a library of enaminonitriles as well as their quinazoline derivatives. The work within also includes the investigation of the [beta]-LG mediated reaction formation of cycloterpenals with natural and unnatural [beta]-methyl aldehydes. We were able to demonstrate that [beta]-LG could mediate the conversion of [alpha],[beta]-unsaturated aldehydes into their corresponding cycloterpenal. In vitro analysis was also performed with store bought milks and the [beta]-LG present was able to mediate the formation of cyclocitral. An in vivo experiment was also performed by utilizing New Zealand White rabbits to demonstrate the formation of cycloretinal within the blood stream by feeding a source of [beta]-LG with retinal. Interestingly, in human blood, [beta]-LG is present at concentrations of 0.7-1.2 g/dL. The protein has been identified within drusen pigments and lipofuscin granules that accumulate in the retina of macular degeneration patients. As humans do not produce beta-lactoglobulin, the source of this protein is from milk and milk products. With these experiments, we clearly demonstrate that under the appropriate conditions, cycloretinal can be produced with [beta]-LG. We have clearly established a direct link between [beta]-LG chemistry and age-related macular degeneration.

Bench, Bennie John

2009-12-01T23:59:59.000Z