Sample records for retinitis pigmentosa rp

  1. Molecular analysis and genetic mapping of the rhodopsin gene in families with autosomal dominant retinitis pigmentosa

    SciTech Connect (OSTI)

    Bunge, S.; Wedemann, H.; Samanns, C.; Horn, M.; Schwinger, E.; Gal, A. (Medizinische Universitaet zu Luebeck (Germany)); David, D. (Laboratorio de Genetica Humana, Lisbon (Portugal)); Terwilliger, D.J.; Ott, J. (Columbia Univ., New York, NY (United States)); Born, L.I. van den (The Netherlands Ophthalmic Research Institute, Amsterdam (Netherlands)) (and others)

    1993-07-01T23:59:59.000Z

    Eighty-eight patients/families with autosomal dominant retinitis pigmentosa (RP) were screened for rhodopsin mutations. Direct sequencing revealed 13 different mutations in a total of 14 (i.e., 16%) unrelated patients. Five of these mutations (T4K, Q28H, R135G, F220C, and C222R) have not been reported so far. In addition, multipoint linkage analysis was performed on two large families with autosomal dominant RP due to rhodopsin mutations by using five DNA probes from 3q21-q24. No tight linkage was found between the rhodopsin locus (RHO) and D3S47 ([theta][sub max] = 0.08). By six-point analysis, RHO was localized in the region between D3S21 and D3S47, with a maximum lod score of 13.447 directly at D3S20. 13 refs., 1 fig., 2 tabs.

  2. Localizing multiple X chromosome-linked retinitis pigmentosa loci using multilocus homogeneity tests

    SciTech Connect (OSTI)

    Ott, J.; Terwilliger, J.D. (New York State Psychiatric Institute, New York (USA)); Bhattacharya, S. (Univ. of Newcastle upon Tyne (England)); Chen, J.D.; Denton, J.; Donald, J. (Prince of Wales Hospital, Randwick (Australia)); Dubay, C.; Litt, M.; Weleber, R.G. (Oregon Health Sciences Univ., Portland (USA)); Farrar, G.J.; Humphries, P. (Trinity College, Dublin (Ireland)); Fishman, G.A.; Wong, F. (Univ. of Illinois, Chicago (USA)); Frey, D.; Maechler, M. (Institute of Medical Genetics, Zurich (Switzerland))

    1990-01-01T23:59:59.000Z

    Multilocus linkage analysis of 62 family pedigrees with X chromosome-linked retinitis pigmentosa (XLRP) was undertaken to determine the presence of possible multiple disease loci and to reliability estimate their map location. Multilocus homogeneity tests furnish convincing evidence for the presence of two XLRP loci, the likelihood ratio being 6.4 {times} 10{sup 9}:1 in a favor of two versus a single XLRP locus and gave accurate estimates for their map location. In 60-75% of the families, location of an XLRP gene was estimated at 1 centimorgan distal to OTC, and in 25-40% of the families, an XLRP locus was located halfway between DXS14 (p58-1) and DXZ1 (Xcen), with an estimated recombination fraction of 25% between the two XLRP loci. There is also good evidence for third XLRP locus, midway between DXS28 (C7) and DXS164 (pERT87), supported by a likelihood ratio of 293:1 for three versus two XLRP loci.

  3. Electrostatic Compensation Restores Trafficking of the Autosomal Recessive Retinitis Pigmentosa E150K Opsin

    E-Print Network [OSTI]

    Palczewski, Krzysztof

    Western Reserve University, Cleveland, Ohio 44106 Rhodopsin is the rod photoreceptor G protein H-IV and H-II. Human E150K and several other closely related opsin mutants were then expressed pigmentosa. When expressed in experimental cell lines or in transgenic rat, pig, mouse, or frog retinas (6

  4. Mastocytosis with urticaria pigmentosa and osteoporosis

    E-Print Network [OSTI]

    Stein, Jennifer A; Kamino, Hideko; Walters, Ruth F; Pomeranz, Miriam K

    2008-01-01T23:59:59.000Z

    pathogenesis of idiopathic osteoporosis in men. Bone 2002;role of mast cells in osteoporosis. Semin Arthritis Rheumurticaria pigmentosa and osteoporosis Jennifer A Stein MD

  5. RP-5 RENEWABLE ENERGY PROJECT

    SciTech Connect (OSTI)

    Neil Clifton; Eliza Jane Whitman; Jamal A. Zughbi

    2003-01-30T23:59:59.000Z

    This is the second quarterly technical report for the RP-5 Renewable Energy Project. The report summarizes the work progress, effort and activities that took place during the period of October 1, 2002 to December 31, 2002. The report has been prepared in accordance with the Department of Energy (DOE) Guidelines. This technical report covers all meetings and discussions that were conducted in order to follow up on potential renewable energy technologies that were identified in the previous report; the technologies were analyzed for their feasibility, suitability and cost effectiveness for this project. This report covers the one-day conceptual design kickoff meeting that took place on November 4, 2002. The meeting was held to discuss the practicality and implementation of potential innovative technologies. Following the kickoff meeting, Inland Empire Utilities Agency (IEUA) and CH2M Hill, the Public Interest Energy Research (PIER) Consultant, held a meeting on December 2, 2002 to discuss the Conceptual Design Report outline and contents in order to clearly present each selected technology along with its evaluation, cost effectiveness and justification. A conference call also took place between the PIER Consultant and IEUA on December 13, 2002, to discuss the overall scope of work for this project. Major project activities in this period include expanded discussions on previous Energy Charrette decisions and recommendations, conceptual design kickoff meeting, conceptual design report, and deciding on the overall project scope of work.

  6. RP-5 RENEWABLE ENERGY PROJECT

    SciTech Connect (OSTI)

    Neil Clifton, P.E.; Eliza Jane Whitman; Jamal A. Zughbi, P.E.

    2002-10-30T23:59:59.000Z

    This report is the first quarterly technical report for the RP-5 Renewable Energy Project. The report summarizes the work progress, effort and activities that took place during the period of July 12, 2002 (project inception) to September 30, 2002. The report has been prepared in accordance with the Department of Energy (DOE) Guidelines. This technical report covers all meetings and discussions that were conducted to identify and analyze potential renewable energy technologies and verify its feasibility and suitability for the project. The report covers the two-day Energy Charrette that was held at the Inland Empire Utilities Agency (IEUA) Headquarters Building on May 8-9, 2002 to brainstorm, evaluate and present all available renewable energy options along with their implementations. Although the Energy Charrette was held prior to awarding of the DOE Grant, the outcome of the Charrette forms the basis of the activities that took place after July 12, 2002. Therefore, the Energy Charrette is frequently referenced and discussed in this report. The report also discusses the Energy Meeting that took place on September 24, 2002 between IEUA and CH2M Hill to follow up on the various presentations and recommendations resulting from the Energy Charrette. It should be noted that no final equipment data or capacities have been presented in the report, as the Conceptual Design has not started yet. This report covers continuing effort and work to complete the Request for Proposal (RFP) for this project. The Executive Summary Section covers more details on the scope of work, which consists of the conceptual, preliminary and final design, and what has been accomplished during the report period. Tools and methods utilized in this project to identify renewable energy technologies are included in the ''Experimental'' Section. Finally, Project achievements, implications and importance in improving this kind of technology are summarized in the ''Conclusion'' Section.

  7. RP-5 Renewable Energy Efficiency Project

    SciTech Connect (OSTI)

    Neil Clifton; Dave Wall; Jamal Zughbi

    2007-06-30T23:59:59.000Z

    This is the final technical report for the RP-5 Renewable Energy Efficiency Project (REEP). The report summarizes, in a comprehensive manner, all the work performed during the award period extending between July 12, 2002 and June 30, 2007. This report has been prepared in accordance with the Department of Energy (DOE) Guidelines and summarizes all of the activities that occurred during the award period. The RP-5 Renewable Energy Efficiency Project, under development by the Inland Empire Utilities Agency (IEUA), is comprised of a series of full-scale demonstration projects that will showcase innovative combinations of primary and secondary generation systems using methane gas derived from local processing of biosolids, dairy manure and other organic material. The goal of the project is to create renewable energy-based generation systems with energy efficiencies 65% or more. The project was constructed at the 15 MGD Regional Wastewater Treatment Plant No. 5 located in the City of Chino in California where the Agency has constructed its new energy-efficient (platinum-LEED rating) headquarters building. Technologies that were featured in the project include internal combustion engines (ICE), absorption chillers, treatment plant secondary effluent cooling systems, heat recovery systems, thermal energy storage (TES), Organic Rankine Cycle (ORC) secondary power generation system, the integration of a future fuel cell system, gas cleaning requirements, and other state-of-the-art design combinations. The RP-5 REEP biogas source is coming from three manure digesters which are located within the RP-5 Complex and are joined with the RP-5 REEP through gas conveyance pipelines. Food waste is being injected into the manure digesters for digester gas production enhancement. The RP-5 REEP clearly demonstrates the biogas production and power generation viability, specifically when dealing with renewable and variable heating value (Btu) fuel. The RP-5 REEP was challenged with meeting stringent utility, gas, power, and air quality rules and regulations. Coordination with the Southern California Gas Company (SCGC), Southern California Edison (SCE), and South Coast Air Quality Management District (SCAQMD) was continuous and extensive. The interconnecting agreement and the permit to construct and operate were major obstacles despite the early start and coordination with the utility companies and regulatory agencies. The RP-5 REEP is part of a unique RP-5 Complex approach where several facilities are tied and connected with each other; where energy and gas can be transferred from one facility to another (see attached RP-5 Complex Ultimate Energy Balance Diagram). The REEP also incorporated new technologies, such as TES and ORC, along with using heat recovery for the platinum-LEED headquarter buildings heating and cooling via efficient absorption chillers. Through the conceptual design phase, numerous innovative technologies were researched and evaluated, with the most proven and efficient selected to be part of the RP-5 REEP.

  8. enter part number BNC / RP-BNC

    E-Print Network [OSTI]

    Berns, Hans-Gerd

    enter part number Products 7/16 1.0/2.3 1.6/5.6 AFI AMC BNC / RP-BNC C FAKRA SMB FME HN MCX Mini ------- Product Search ------- Inventory Search Search Results for: 31-10152-RFX Results: 1 - 1 of 1 Part Number. All rights reserved. Copyright | Terms & Conditions | RF E-Mail Client | Contact Us | Amphenol

  9. RP-5 Renewable Energy Efficiency Project

    SciTech Connect (OSTI)

    Neil Clifton; Eliza Jane Whitman; Jamal A. Zughbi

    2003-07-28T23:59:59.000Z

    This is the fourth quarterly technical report for the RP-5 Renewable Energy Efficiency Project. The report summarizes the work progress, effort and activities that took place during the period of April 1, 2003 to June 30, 2003. However, IEUA is preparing a Supplemental report that will be mailed to the Department of Energy (DOE) by August 1, 2003, that provides additional information regarding IEUA's plan to expedite certain project activities. The report has been prepared in accordance with the Department of Energy (DOE) Guidelines. This technical report covers all meetings, discussions, and engineering and design activities that took place to finalize the project scope of work and complete the Request for Proposal (RFP) for the RP-5 Renewable Energy Efficiency Project. IEUA has decided to invite three more consulting engineering firms besides CH2M Hill, the Public Interest Energy Research (PIER) Consultant, to submit proposals for the design of the energy efficiency project. The proposals are currently in the evaluation phase and a decision is expected by the end of July. IEUA moved to its new headquarters building on June 13, 2003. The central plant is the system that supplies cooling and heating water to the headquarters building, and it primarily consists of equipment listed in the cooperative agreement under ''Chiller and Heater''. The central plant equipment was successfully installed and started. Other activities include gas analysis of three sources of low quality digester gas and foul air which could be used as fuel for an innovative flex microturbine. IEUA is also working with Stirling Energy Systems to determine if the Agency should be a host site for their equipment for testing the engine's operation on digester and natural gas. A matching funds update is also included in the Results and Discussion section, which presents the work effort performed by the PIER Consultant and the associated costs that serve as matching funds for the RP-5 Project during this report period.

  10. IPSJ SIG Technical Report RP2 OSCAR API API

    E-Print Network [OSTI]

    Kasahara, Hironori

    #12;IPSJ SIG Technical Report 5 OSCAR API Fig. 5 Structure of OSCAR API standard translator and DeIPSJ SIG Technical Report OSCAR API 1 1 1 1 1 1 OSCAR SH4A 8 RP2 OSCAR API API RP2 8 SPEC CPU 2000 ART 1.16 1. 64 80 1 [7][8] , [9] 1 1 Waseda Universoty [10] OSCAR [1] [5] RP-2 [6] OSCAR OSCAR API[2

  11. RP-5 Renewable Energy Efficiency Project

    SciTech Connect (OSTI)

    Neil Clifton; Eliza Jane Whitman; Jamal A. Zughbi

    2004-01-29T23:59:59.000Z

    This is the sixth quarterly technical report for the RP-5 Renewable Energy Efficiency Project. The report summarizes the work progress, effort and activities that took place during the period from October 1, 2003 through December 31, 2003. The report has been prepared in accordance with the Department of Energy (DOE) Guidelines. In coordination with the DOE, IEUA has revised the original Cooperative Agreement to reflect the actual and current project scope of work. The original Agreement statement of work (SOW) included conceptual and preliminary equipment and systems, which were further evaluated for feasibility and suitability for the project. As a result, some of the equipment was taken out of the project scope. In response to questions from the DOE, IEUA has submitted a summary report on the Organic Rankine Cycle (ORC) secondary power generation units for availability and suitability for this project and associated safety concerns pointed out by the DOE. IEUA has awarded the consulting engineering contract to Parsons Water and Infrastructure, Inc. to provide the project's design and construction services. The project's pre-design kickoff meeting was held at IEUA's headquarters on December 11, 2003. IEUA has submitted a proposal for a grant offered by California Energy Commission (CEC) which if awarded to IEUA, will add value to this project. IEUA has finalized and signed the agreement with Stirling Energy Systems (SES) to host a 25 kW Stirling Engine at the RP-5 plant site for reliability and performance testing using digester and natural gas. As a result of further evaluation of the flexible microturbine system, IEUA has decided to take it out of the project's scope of work; however, it may be considered in future projects at other locations. IEUA has installed a 60 kW Photovoltaic (PV) power generation system on the roof of the new headquarters building. A matching funds update is also included in the Results and Discussion section. The update presents the work effort performed by CH2M Hill, the PIER Consultant, and the associated costs that serve as matching funds for the RP-5 Renewable Energy Efficiency Project during this report period.

  12. RpA ratio: total shadowing due to running coupling

    E-Print Network [OSTI]

    E. Iancu; D. N. Triantafyllopoulos

    2007-07-02T23:59:59.000Z

    We predict that the RpA ratio at the most forward rapidities to be measured at LHC should be strongly suppressed, close to "total shadowing'' (RpA = A^(-1/3)), as a consequence of running coupling effects in the nonlinear QCD evolution.

  13. Flexible retinal electrode array

    DOE Patents [OSTI]

    Okandan, Murat (Albuquerque, NM); Wessendorf, Kurt O. (Albuquerque, NM); Christenson, Todd R. (Albuquerque, NM)

    2006-10-24T23:59:59.000Z

    An electrode array which has applications for neural stimulation and sensing. The electrode array can include a large number of electrodes each of which is flexibly attached to a common substrate using a plurality of springs to allow the electrodes to move independently. The electrode array can be formed from a combination of bulk and surface micromachining, with electrode tips that can include an electroplated metal (e.g. platinum, iridium, gold or titanium) or a metal oxide (e.g. iridium oxide) for biocompatibility. The electrode array can be used to form a part of a neural prosthesis, and is particularly well adapted for use in an implantable retinal prosthesis where the electrodes can be tailored to provide a uniform gentle contact pressure with optional sensing of this contact pressure at one or more of the electrodes.

  14. astrophysical rp process: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    to the CNO reactions will certainly be of importance as they are closely related to the solar neutrino fluxes and the rp process. Moreover, according to the present results,...

  15. Alpha Emission Near 100Sn and the Termination of the rp Process

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Alpha Emission Near 100 Sn and the Termination of the rp Process The astrophysical rp-process is thought to reach a termination point in the region of 100 Sn, via the...

  16. Photovoltaic retinal prosthesis with high pixel density

    E-Print Network [OSTI]

    Palanker, Daniel

    Photovoltaic retinal prosthesis with high pixel density Keith Mathieson1,4 , James Loudin1 to stimulating electrodes via intraocular cables. We present a photovoltaic subretinal prosthesis, in which pixel, demonstrating the possibility of a fully integrated photovoltaic retinal prosthesis with high

  17. Integrated computational system for portable retinal imaging

    E-Print Network [OSTI]

    Boggess, Jason (Jason Robert)

    2012-01-01T23:59:59.000Z

    This thesis introduces a system to improve image quality obtained from a low-light CMOS camera-specifically designed to image the surface of the retina. The retinal tissue, as well as having various diseases of its own, ...

  18. VIRTIS for Doc: ROS-LES-RP-XXX Title: VIRTIS-H Calibration

    E-Print Network [OSTI]

    Demoulin, Pascal

    VIRTIS for Doc: ROS-LES-RP-XXX Title: VIRTIS-H Calibration Author: JM REESS / F. HENRY Date: 13: ROS-LES-RP-XXX Title: VIRTIS-H Calibration Author: JM REESS / F. HENRY Date: 13/06/2013 Issue: 1 Reason of the modification 1.0 13/06/13 JMR First Issue #12;VIRTIS for Doc: ROS-LES-RP-XXX Title: VIRTIS

  19. RETINAL BLOOD VESSEL SEGMENTATION USING GEODESIC VOTING METHODS Youssef Rouchdy

    E-Print Network [OSTI]

    Cohen, Laurent

    RETINAL BLOOD VESSEL SEGMENTATION USING GEODESIC VOTING METHODS Youssef Rouchdy and Laurent D to segment retinal blood vessels are presented. Many authors have used minimal cost paths, or similarly on the use of a set of such geodesic paths to extract retinal blood vessels, using minimal interaction

  20. Request for Proposals (RFP) Number DE-RP36-07GO97036: Alliance...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Request for Proposals (RFP) Number DE-RP36-07GO97036: Alliance Prime Contract No. DE-AC36-08GO28308, through Modification M801 Request for Proposals (RFP) Number DE-RP36-07GO97036:...

  1. Benchmarking Wireless Network Protocols: Threat and Challenge Analysis of the AeroRP

    E-Print Network [OSTI]

    Broyles, Dan

    2011-06-24T23:59:59.000Z

    , OLSR, DSDV, and AeroRP that is part of the Aero protocol stack developed at The University of Kansas. AeroRP outperforms the traditional MANET routing protocols in benchmarks that involve either highly-dynamic networks or disruptions in connectivity....

  2. The Effects of {beta}-Delayed Proton Emission on the Path of the rp-Process

    SciTech Connect (OSTI)

    Boyd, R.N.

    2000-12-31T23:59:59.000Z

    The rp-process occurs in a hot hydrogen-rich stellar environment. Its trajectory passes through the most proton-rich nuclides in the periodic table. It has long been thought to be responsible for synthesizing at least the light p-process nuclides. Thus these nuclides can provide signatures for rp-process nucleosynthesis. Difficulties with various rp-process scenarios often focus on {sup 92,94}Mo and {sup 96,98}Ru p-nuclides, as their anomalously large abundances are difficult to produce in any model of nucleosynthesis. However, it now appears that they might be produced in the rp-process resulting from accretion onto a neutron star. If the rp-process does synthesize these nuclides, {beta}-delayed proton emission might well resolve some of the difficulties made evident by the model calculations.

  3. Application of a new screening model to thermonuclear reactions of the rp process

    E-Print Network [OSTI]

    Theodore Liolios

    2003-05-09T23:59:59.000Z

    A new screening model for astrophysical thermonuclear reactions was derived recently which improved Salpeter's weak-screening one. In the present work we prove that the new model can also give very reliable screening enhancement factors (SEFs) when applied to the rp process. According to the results of the new model, which agree well with Mitler's SEFs, the screened rp reaction rates can be, at most, twice as fast as the unscreened ones.

  4. Second harmonic imaging of membrane potential of neurons with retinal

    E-Print Network [OSTI]

    Columbia University

    Second harmonic imaging of membrane potential of neurons with retinal Boaz A. Nemet Volodymyr of neurons, using the nonlinear optical phenom- enon of second harmonic generation (SHG) with a photopigment reti- nal as the chromophore [second harmonic retinal imaging of mem- brane potential (SHRIMP)]. We

  5. Weak interaction rates for Kr and Sr waiting-point nuclei under rp-process conditions

    E-Print Network [OSTI]

    P. Sarriguren

    2009-10-06T23:59:59.000Z

    Weak interaction rates are studied in neutron deficient Kr and Sr waiting-point isotopes in ranges of densities and temperatures relevant for the rp-process. The nuclear structure is described within a microscopic model (deformed QRPA) that reproduces not only the half-lives but also the Gamow-Teller strength distributions recently measured. The various sensitivities of the decay rates to both density and temperature are discussed. Continuum electron capture is shown to contribute significantly to the weak rates at rp-process conditions.

  6. DISSERTATION CHALLENGES AND SOLUTIONS IN COMBINING RP AND SP DATA TO VALUE

    E-Print Network [OSTI]

    DISSERTATION CHALLENGES AND SOLUTIONS IN COMBINING RP AND SP DATA TO VALUE RECREATION Submitted 2008 #12;iii ABSTRACT OF DISSERTATION CHALLENGES AND SOLUTIONS IN COMBINING RPAND SP DATA TO VALUE recommendations we present as economists. This dissertation looks at joining two of the most commonly used non

  7. Framework for Coupling Room Air Models to Heat Balance Model Load and Energy Calculations (RP-1222)

    E-Print Network [OSTI]

    Chen, Qingyan "Yan"

    1 Framework for Coupling Room Air Models to Heat Balance Model Load and Energy Calculations (RP in a program for hourly load calculations of a single thermal zone. The heat balance model for load and energy to heat balance model load and energy calculations," HVAC&R Research, 10(2), 91-111. #12;2 · Mixed

  8. Convective heat transfer characteristics of China RP-3 aviation kerosene at supercritical pressure

    E-Print Network [OSTI]

    Guo, Zhixiong "James"

    Convective heat transfer characteristics of China RP-3 aviation kerosene at supercritical pressure Keywords: Supercritical pressure Aviation kerosene Convective heat transfer Numerical study a b s t r a c convective in kerosene pipe flow is complicated. Here the convective heat transfer characteristics of China

  9. BN-97-4-4 (RP-875) The Radiant Time Series Cooling

    E-Print Network [OSTI]

    of the proceduresare described in chapters 2 and 10 of the current ASHRAECool#zg and Heating LoadCalculation ManualBN-97-4-4 (RP-875) The Radiant Time Series Cooling Load Calculation Procedure Jeffrey D. Spitler calculations, derived from the heat balancemethod.It effectively replacesall other simpli- fied (non-heat

  10. Job submission to grid computing environments RP Bruin, TOH White, AM Walker, KF Austen, MT Dove

    E-Print Network [OSTI]

    Cambridge, University of

    Job submission to grid computing environments RP Bruin, TOH White, AM Walker, KF Austen, MT Dove Albemarle Street, London W1S 4BS Abstract The problem of enabling scientist users to submit jobs to grid scientists to work with raw Globus job-submission commands ­ in the end they are likely to end up

  11. The role of excited states in rp-process for sd shell nuclei

    E-Print Network [OSTI]

    J. Grineviciute; B. A. Brown; H. Schatz

    2014-04-29T23:59:59.000Z

    We investigate the importance of proton capture on low-lying excited states that are thermally excited in hot stellar environments. In addition to the previously known case of $^{32}$Cl$(p,\\gamma)^{33}$Ar we find several other sd-shell nuclei with large stellar enhancement factors. We discuss the uncertainty this introduces into rp-process nucleosynthesis.

  12. The Reduction of Retinal Autofluorescence Caused by Light Exposure

    E-Print Network [OSTI]

    is important because several clinical procedures (such as slit- lamp examination, fundus photography has led to the theory that light exposure plays a role in some retinal diseases including age

  13. Radiosensitization by a new nucleoside analogue: 1-(2-hydroxy-1-(hydroxymethyl)ethoxy)methyl-2-nitroimidazole (RP-170)

    SciTech Connect (OSTI)

    Murayama, C.; Suzuki, A.; Suzuki, T.; Miyata, Y.; Sakaguchi, M.; Tanabe, Y.; Tanaka, N.; Mori, T. (Tokai Univ. (Japan))

    1989-09-01T23:59:59.000Z

    A new potent hypoxic cell sensitizer, a 2-nitroimidazole nucleoside analogue having methoxyglycerol as a sugar moiety at the N-1 position of the imidazole ring (RP-170), has been synthesized. Its radiosensitizing activities in vitro and in vivo were investigated and compared with those of misonidazole (MISO) and etanidazole (SR-2508). As might be expected from the almost identical electron affinities of the three compounds, they were equally effective against hypoxic EMT6 cells in vitro. The in vivo-in vitro excision analysis showed that RP-170 was also as effective as MISO and etanidazole to radiosensitize solid tumor cells in vivo. An intraperitoneal administration of 200 mg/kg of RP-170 and an intravenous administration of the same dose of etanidazole showed an equal sensitizer-enhancement ratio of 1.51 to solid EMT6/KU tumors. Its effectiveness was also demonstrated by growth delay assay using solid SCCVII tumors. As predicted from the low partition coefficient, RP-170 and etanidazole showed apparently lower toxicity in vivo than MISO; their LD50/14 were 4.3, 4.8, and 1.8 g/kg in our experiment, respectively. Moreover, RP-170 showed fast clearance from serum in mice (t1/2 = 10.24 min) and poor penetration into neural tissues. Although RP-170 does not show any advantages over etanidazole in terms of sensitization or toxicity, RP-170 might be preferable under certain circumstances because it can be given orally.

  14. Retinal response of Macaca mulatta to picosecond laser pulses of varying energy and spot size

    E-Print Network [OSTI]

    Roach, William P.

    We investigate the relationship between the laser beam at the retina (spot size) and the extent of retinal injury from single ultrashort laser pulses. From previous studies it is believed that the retinal effect of single ...

  15. Retinal and post-retinal contributions to the quantum efficiency of the human eye

    E-Print Network [OSTI]

    Gibran Manasseh; Chloe de Balthasar; Bruno Sanguinetti; Enrico Pomarico; Nicolas Gisin; Rolando Grave de Peralta; Sara L. Gonzalez

    2012-08-08T23:59:59.000Z

    The retina is one of the best known quantum detectors with rods able to respond to a single photon. However, estimates on the number of photons eliciting conscious perception, based on signal detection theory, are systematically above these values. One possibility is that post-retinal processing significantly contributes to the decrease in the quantum efficiency determined by signal detection. We carried out experiments in humans using controlled sources of light while recording EEG and reaction times. Half of the participants behaved as noisy detectors reporting perception in trials where no light was sent. DN subjects were significantly faster to take decisions. Reaction times significantly increased with the decrease in the number of photons. This trend was reflected in the latency and onset of the EEG responses over frontal and parietal contacts where the first significant differences in latency comparable to differences in reaction time appeared. Delays in latency of neural responses across intensities were observed later over visual areas suggesting that they are due to the time required to reach the decision threshold in decision areas rather than to longer integration times at sensory areas. Our results suggest that post-retinal processing significantly contribute to increase detection noise and thresholds, decreasing the efficiency of the retina brain detector system.

  16. RSAC 6.2 with WinRP 2.0 User Manual

    SciTech Connect (OSTI)

    Bradley Schrader

    2005-09-01T23:59:59.000Z

    The Radiological Safety Analysis Computer Program (RSAC-6.2) calculates the consequences of a release of radionuclides to the atmosphere. Using a personal computer, a user can generate a fission product inventory from either reactor operating history or a nuclear criticality accident. RSAC-6.2 models the effects of high-efficiency particulate air filters or other cleanup systems and calculates decay and ingrowth during transport through processes, facilities, and the environment. Doses are calculated for resuspension, inhalation, immersion, ground surface, and ingestion pathways. WinRP 2.0, a windows based overlay to RSAC-6.2, assists users in creating and running RSAC-6.2 input files. This users manual contains the mathematical models and operating instructions for RSAC-6.2 and WinRP 2.0. Instructions, screens, and examples are provided to guide the user through the functions provided by RSAC-6.2 and WinRP 2.0. These programs are designed for users who are familiar with radiological dose assessment methods.

  17. PROGRESS TOWARDS A HIGH-RESOLUTION RETINAL PROSTHESIS James D. Weiland1

    E-Print Network [OSTI]

    Arizona, University of

    PROGRESS TOWARDS A HIGH-RESOLUTION RETINAL PROSTHESIS James D. Weiland1 , Wolfgang Fink2,1 , Mark, and stimulating electrodes. Keywords ­ retinal prosthesis, microsystems, electrical stimulation, neural prostheses year.[1] One proposed treatment for these conditions is a retinal prosthesis that will stimulate

  18. Loss of Daylight Vision in Retinal Degeneration: Are

    E-Print Network [OSTI]

    Tabin, Cliff

    Loss of Daylight Vision in Retinal Degeneration: Are Oxidative Stress and Metabolic Dysregulation, particularly in cones, the type of photoreceptors that mediate daylight and color vision. The evidence, providing our daylight vision, and have many of the same features and vulnerabilities as rod photoreceptors

  19. Effects of Methanol on the Retinal Function of Juvenile Rats

    E-Print Network [OSTI]

    Casanova, Christian

    Effects of Methanol on the Retinal Function of Juvenile Rats C. Plaziac1 , P. Lachapelle2 , C Received 18 April 2002; accepted 22 July 2002 Abstract We have investigated the effect of methanol exposure recorded prior to and up to 72 h after the administration of methanol. Data were compared to a control

  20. Blood Flow Magnetic Resonance Imaging of Retinal Degeneration

    E-Print Network [OSTI]

    Duong, Timothy Q.

    Blood Flow Magnetic Resonance Imaging of Retinal Degeneration Yingxia Li,1 Haiying Cheng,1 Qiang. Duong1,2,3,4,5,6,7 PURPOSE. This study aims to investigate quantitative basal blood flow as well as hypercapnia- and hyperoxia-induced blood flow changes in the retinas of the Royal College of Surgeons (RCS

  1. Towards wide-field high-resolution retinal imaging

    E-Print Network [OSTI]

    Kellerer, Aglae

    2015-01-01T23:59:59.000Z

    Adaptive optical correction is an efficient technique to obtain high-resolution images of the retinal surface. A main limitation of adaptive optical correction, however, is the small size of the corrected image. For medical purposes it is important to increase the size of the corrected images. This can be done through composite imaging, but a major difficulty is then the introduction of reconstruction artifacts. Another approach is multi-conjugate adaptive optics. MCAO comes in two flavors. The star- oriented approach has been demonstrated on the eye and allows to increase the diameter of the corrected image by a factor of approximately 2-3. Difficulties in the tomographic reconstruction precludes the correction of larger fields. Here we have investigate the possibility to apply a layer-oriented MCAO approach to retinal imaging.

  2. Retinal arteriolar geometry is associated with cerebral white matter hyperintensities on MRI 

    E-Print Network [OSTI]

    Doubal, F.N.; de Haan, R; MacGillivray, T.J.; Cohn-Hokke, P.; Dhillon, B.; Dennis, M.S.; Wardlaw, J.M.

    Background. Cerebral small vessel disease (lacunar stroke and cerebral white matter hyperintensities) is caused by vessel abnormalities of unknown aetiology. Retinal vessels show developmental and pathophysiological ...

  3. he application of rapid prototyping (RP) in fabricat-ing nonassembly robotic systems with inserts is pre-

    E-Print Network [OSTI]

    Mavroidis, Constantinos

    T he application of rapid prototyping (RP) in fabricat- ing nonassembly robotic systems for the rapid and automatic design and fabrication of robotic sys- tems a reality is to study the application with inserts is pre- sented in this article. The development of robotic systems that have all necessary

  4. FLATNESS EVALUATION FOR A V-FLASH RAPID PROTOTYPE (RP) MACHINE Abdon Godinez Velasco, Mohammed Anazi, Gaurav Ameta

    E-Print Network [OSTI]

    Collins, Gary S.

    of the object. There are two main types of RP: · Subtractive Manufacturing · Additive Manufacturing This research focuses on additive manufacturing (AM). V- Flash is a machine (see figure 1) that uses Engineering ,Washington State University, Pullman WA 99164 Abstract In today`s society manufacturing is very

  5. Books and articles that have drawn on the resources of the Michigan Tech Archives NHPRC Application #RP-50059

    E-Print Network [OSTI]

    Books and articles that have drawn on the resources of the Michigan Tech Archives NHPRC Application Series, forthcoming). #12;Publication List - RP-50059 - Michigan Tech - Page 2 Books, Articles. (The Netherlands: Kluwer Academic Publishers, 2008) 2:1680-1685. Anderson, George, and Richard Taylor

  6. UTS:LIBRARY AUG08/UTS:CRICOS CODE 00099F / RP080805 Filming at the UTS Library

    E-Print Network [OSTI]

    University of Technology, Sydney

    UTS:LIBRARY AUG08/UTS:CRICOS CODE 00099F / RP080805 Filming at the UTS Library: APPLICATION TO FILM WWW.LIB.UTS.EDU.AU UTS LIBRARY: FACILITIES Please send this completed form to: Director, Library Client Services Unit Level 3, Blake Library (City Campus) Corner Quay Street & Ultimo Road Haymarket, NSW

  7. SPIE Proceedings BIOS 2005, Ophthalmic Technologies XV, vol. 5688A, paper 37 Towards High-Resolution Optoelectronic Retinal Prosthesis

    E-Print Network [OSTI]

    Palanker, Daniel

    -Resolution Optoelectronic Retinal Prosthesis Daniel Palankera,b , Philip Huiea,b , Alexander Vankovb , Alon Ashera , Steven neural stimulation is also examined. Key words: Retinal prosthesis, neural cell stimulation, visual

  8. An Image Analysis System for the Assessment of Retinal Microcirculation in Hypertension and Its Clinical Evaluation

    E-Print Network [OSTI]

    Markatos, Evangelos P.

    An Image Analysis System for the Assessment of Retinal Microcirculation in Hypertension and Its, Greece Abstract-- A system for the assessment of hypertension through the measurement of retinal vessels worldwide [4]. Hypertension (high blood pressure) is one of the most important, highly prevalent

  9. Optical Coherence Tomography Scan Circle Location and Mean Retinal Nerve Fiber Layer

    E-Print Network [OSTI]

    Srinivasan, Vivek J.

    Optical Coherence Tomography Scan Circle Location and Mean Retinal Nerve Fiber Layer Measurement) retinal nerve fiber layer (RNFL) thickness mea- surements of varying the standard 3.4-mm-diameter circle of the variable circle placement effect. RNFL thickness was measured on this three-dimensional dataset by using

  10. The Boston Retinal Prosthesis A 15-Channel Hermetic Wireless Neural Stimulator

    E-Print Network [OSTI]

    Kelly, Shawn K.

    The Boston Retinal Prosthesis A 15-Channel Hermetic Wireless Neural Stimulator Shawn K. Kelly-- A miniaturized, hermetically-encased, wirelessly- operated retinal prosthesis has been developed for pre-clinical studies in Yucatan minipig animal models. The prosthesis attaches conformally to the outside of the eye

  11. JOURNAL OF BIOLOGICAL RHYTHMS / April 2000Bryant et al. / RETINAL INNERVATION OF CALBINDIN SCN NEURONS Retinal Innervation of Calbindin-D28K

    E-Print Network [OSTI]

    Silver, Rae

    JOURNAL OF BIOLOGICAL RHYTHMS / April 2000Bryant et al. / RETINAL INNERVATION OF CALBINDIN SCN: Ultrastructural Characterization Damani N. Bryant,* Joseph LeSauter, Rae Silver,,,§ and Maria-Teresa Romero*,1

  12. Tri-functional cannula for retinal endovascular surgery

    DOE Patents [OSTI]

    Weiss, Jonathan D. (Albuquerque, NM)

    2010-07-27T23:59:59.000Z

    A tri-functional cannula combines the functions of tissue Plasminogen Activator (tPA) solution delivery, illumination and venous pressure measurement. The cannula utilizes a tapered hollow-core optical fiber having an inlet for tPA solution, an attached fiber optic splitter configured to receive illumination light from an optical source such and a LED. A window in the cannula transmits the light to and from a central retinal vein. The return light is coupled to an optical detector to measure the pressure within the vein and determine whether an occlusion has been removed.

  13. The rp Process Ashes from Stable Nuclear Burning on an Accreting Neutron Star

    E-Print Network [OSTI]

    Hendrik Schatz; Lars Bildsten; Andrew Cumming; Michael Wiescher

    1999-05-20T23:59:59.000Z

    We calculate the nucleosynthesis during stable nuclear burning on an accreting neutron star. This is appropriate for weakly magnetic neutron stars accreting at near-Eddington rates in low mass X-ray binaries, and for most accreting X-ray pulsars. We show that the nuclear burning proceeds via the rapid proton capture process (rp process), and makes nuclei far beyond the iron group. The final mixture of nuclei consists of elements with a range of masses between approximately A=60 and A=100. The average nuclear mass of the ashes is set by the extent of helium burning via (alpha,p) reactions, and depends on the local accretion rate. Our results imply that the crust of these accreting neutron stars is made from a complex mixture of heavy nuclei, with important implications for its thermal, electrical and structural properties. A crustal lattice as impure as our results suggest will have a conductivity set mostly by impurity scattering, allowing more rapid Ohmic diffusion of magnetic fields than previously estimated.

  14. The Boston retinal prosthesis a 15-channel hermetic wireless neural stimulator

    E-Print Network [OSTI]

    Wyatt, John L.

    A miniaturized, hermetically-encased, wirelessly-operated retinal prosthesis has been developed for pre-clinical studies in Yucatan minipig animal models. The prosthesis attaches conformally to the outside of the eye and ...

  15. Retinal blood flow measurement with ultrahigh-speed swept-source / Fourier domain optical coherence tomography

    E-Print Network [OSTI]

    Baumann, Bernhard

    Doppler OCT is a functional extension of OCT that provides information on flow in biological tissues. We present a novel approach for total retinal blood flow assessment using ultrahigh speed Doppler OCT. A swept source / ...

  16. Novel KRIT1/CCM1 mutation in a patient with retinal cavernous hemangioma and cerebral cavernous malformation

    E-Print Network [OSTI]

    Reddy, Shantan; Gorin, Michael B.; McCannel, Tara A.; Tsui, Irena; Straatsma, Bradley R.

    2010-01-01T23:59:59.000Z

    in patients who have both CCMs and retinal cavernouscavernous hemangioma and a CCM. Methods and results Thecavernous malformations (CCM). Distinct mutations have been

  17. Honokiol inhibits pathological retinal neovascularization in oxygen-induced retinopathy mouse model

    SciTech Connect (OSTI)

    Vavilala, Divya Teja [Division of Pharmaceutical Sciences, School of Pharmacy, University of Missouri-Kansas City, MO (United States)] [Division of Pharmaceutical Sciences, School of Pharmacy, University of Missouri-Kansas City, MO (United States); O’Bryhim, Bliss E. [Department of Ophthalmology, University of Kansas Medical Center, Kansas City, KS (United States)] [Department of Ophthalmology, University of Kansas Medical Center, Kansas City, KS (United States); Ponnaluri, V.K. Chaithanya [Division of Pharmaceutical Sciences, School of Pharmacy, University of Missouri-Kansas City, MO (United States)] [Division of Pharmaceutical Sciences, School of Pharmacy, University of Missouri-Kansas City, MO (United States); White, R. Sid; Radel, Jeff [Department of Ophthalmology, University of Kansas Medical Center, Kansas City, KS (United States)] [Department of Ophthalmology, University of Kansas Medical Center, Kansas City, KS (United States); Symons, R.C. Andrew [Department of Ophthalmology, University of Kansas Medical Center, Kansas City, KS (United States) [Department of Ophthalmology, University of Kansas Medical Center, Kansas City, KS (United States); Ophthalmology Department, Royal Melbourne Hospital, University of Melbourne, Victoria (Australia); Department of Surgery, Royal Melbourne Hospital, University of Melbourne, Victoria (Australia); Mukherji, Mridul, E-mail: mukherjim@umkc.edu [Division of Pharmaceutical Sciences, School of Pharmacy, University of Missouri-Kansas City, MO (United States)] [Division of Pharmaceutical Sciences, School of Pharmacy, University of Missouri-Kansas City, MO (United States)

    2013-09-06T23:59:59.000Z

    Highlights: •Aberrant activation of HIF pathway is the underlying cause of ischemic neovascularization. •Honokiol has better therapeutic index as a HIF inhibitor than digoxin and doxorubicin. •Daily IP injection of honokiol in OIR mouse model reduced retinal neovascularization. •Honokiol also prevents vaso-obliteration, the characteristic feature of the OIR model. •Honokiol enhanced physiological revascularization of the retinal vascular plexuses. -- Abstract: Aberrant activation of the hypoxia inducible factor (HIF) pathway is the underlying cause of retinal neovascularization, one of the most common causes of blindness worldwide. The HIF pathway also plays critical roles during tumor angiogenesis and cancer stem cell transformation. We have recently shown that honokiol is a potent inhibitor of the HIF pathway in a number of cancer and retinal pigment epithelial cell lines. Here we evaluate the safety and efficacy of honokiol, digoxin, and doxorubicin, three recently identified HIF inhibitors from natural sources. Our studies show that honokiol has a better safety to efficacy profile as a HIF inhibitor than digoxin and doxorubicin. Further, we show for the first time that daily intraperitoneal injection of honokiol starting at postnatal day (P) 12 in an oxygen-induced retinopathy (OIR) mouse model significantly reduced retinal neovascularization at P17. Administration of honokiol also prevents the oxygen-induced central retinal vaso-obliteration, characteristic feature of the OIR model. Additionally, honokiol enhanced physiological revascularization of the retinal vascular plexuses. Since honokiol suppresses multiple pathways activated by HIF, in addition to the VEGF signaling, it may provide advantages over current treatments utilizing specific VEGF antagonists for ocular neovascular diseases and cancers.

  18. Photovoltaic retinal prosthesis: implant fabrication and performance This article has been downloaded from IOPscience. Please scroll down to see the full text article.

    E-Print Network [OSTI]

    Palanker, Daniel

    Photovoltaic retinal prosthesis: implant fabrication and performance This article has been (11pp) doi:10.1088/1741-2560/9/4/046014 Photovoltaic retinal prosthesis: implant fabrication/046014 Abstract The objective of this work is to develop and test a photovoltaic retinal prosthesis for restoring

  19. Ophthalmic Technologies XVII, SPIE, vol. 6426A, 2007 1 Progress Towards a High-Resolution Retinal Prosthesis

    E-Print Network [OSTI]

    Palanker, Daniel

    Prosthesis Alex Butterwick*a , Alex Vankov a,b , Phil Huie a,b , Karthik Vijayraghavan a , Jim Loudin trans-scleral cable. 3-dimensional structures in the subretinal prosthesis induce retinal migration formation of a fibrotic seal has been observed. Keywords: Retinal Prosthesis, Neural Interface 1

  20. A homozygous mutation in the TUB gene associated with retinal dystrophy and obesity

    E-Print Network [OSTI]

    Borman, Arundhati Dev; Pearce, Laura R.; Mackay, Donna S.; Nagel-Wolfrum, Kerstin; Davidson, Alice E.; Henderson, Robert; Garg, Sumedha; Waseem, Naushin H.; Webster, Andrew R.; Plagnol, Vincent; Wolfrum, Uwe; Farooqi, I. Sadaf; Moore, Anthony T.

    2013-12-20T23:59:59.000Z

    of RP, are referred to as “ciliopathies” as they are caused by mutations in genes important for the generation and maintenance of cilia [Waters and Beales, 2011]. The Tubby-like proteins (TUB, TULP1, TULP2, and TULP3) are a unique family of proteins... mutations in patients with Leber congenital amaurosis and juvenile RP by genome-wide homozygosity mapping with SNP microarrays. Invest Ophthalmol Vis Sci 48:5690–5698. Gilliam JC, Chang JT, Sandoval IM, Zhang Y, Li T, Pittler SJ, Chiu W, Wensel TG. 2012...

  1. Method and system for the diagnosis of disease using retinal image content and an archive of diagnosed human patient data

    DOE Patents [OSTI]

    Tobin, Kenneth W; Karnowski, Thomas P; Chaum, Edward

    2013-08-06T23:59:59.000Z

    A method for diagnosing diseases having retinal manifestations including retinal pathologies includes the steps of providing a CBIR system including an archive of stored digital retinal photography images and diagnosed patient data corresponding to the retinal photography images, the stored images each indexed in a CBIR database using a plurality of feature vectors, the feature vectors corresponding to distinct descriptive characteristics of the stored images. A query image of the retina of a patient is obtained. Using image processing, regions or structures in the query image are identified. The regions or structures are then described using the plurality of feature vectors. At least one relevant stored image from the archive based on similarity to the regions or structures is retrieved, and an eye disease or a disease having retinal manifestations in the patient is diagnosed based on the diagnosed patient data associated with the relevant stored image(s).

  2. Protein Induced Torsion of the Retinal Chromophore and How it Affects the Photochemistry of Rhopdopsin

    SciTech Connect (OSTI)

    Weingart, Oliver; Buss, Volker [Theoretische Chemie, Universitaet Duisburg-Essen, Universitaetsstr. 2 D-45141 Essen (Germany)

    2007-12-26T23:59:59.000Z

    The influence of protein induced chromophore deformations on reaction timescale and quantum yield is investigated using ab initio molecular dynamics in vacuo on four and five double bond models of the retinal chromophore. The opposite twist of the C11 = C12 and the C12-C13 bonds appears to be the prerequisite for the highly stereoselective and efficient cis-trans photodynamics of the retinal chromophore in the binding pocket of rhodopsin. The formation of the photoproduct is determined by the phase of the hydrogen out-of-plane mode of the 11-cis double bond.

  3. In-vivo Performance of Photovoltaic Subretinal Prosthesis Yossi Mandel1,2

    E-Print Network [OSTI]

    Palanker, Daniel

    In-vivo Performance of Photovoltaic Subretinal Prosthesis Yossi Mandel1,2 , Georges Goetz1 prosthesis, in which camera-captured images are projected onto the retina using pulsed near-IR light. Each blinded by retinal degenerative diseases. Keywords: retinal prosthesis, retinitis pigmentosa, photodiode

  4. Wireless Sensor Network, 2010, 2, 441-446 doi:10.4236/wsn.2010.26055 Published Online June 2010 (http://www.SciRP.org/journal/wsn)

    E-Print Network [OSTI]

    Kuzmanov, Georgi

    (http://www.SciRP.org/journal/wsn) Copyright © 2010 SciRes. WSN Practical Considerations for Wireless and envisaged applications in Wireless Sensor Networks (WSNs). The WSN community that has formed over the years is divided into two sub-communities: the systems sub-community and the theory sub-community. However

  5. A model of high-frequency oscillatory potentials in retinal ganglion cells

    E-Print Network [OSTI]

    Theiler, James

    and are only weakly stimulus locked. In the retinal model, this phase variability resulted from the nonlinear to become phase locked, but did not synchronize separate regions. Model-generated HFOPs were consistent, by negative feedback from axon-bearing amacrine cells excited via electrical synapses with neighboring

  6. Propagation of Intercellular Calcium Waves in Retinal Astrocytes and Mu ller Cells

    E-Print Network [OSTI]

    Newman, Eric A.

    Propagation of Intercellular Calcium Waves in Retinal Astrocytes and Mu¨ ller Cells Eric A. Newman. Experiments were conducted to determine the mechanism of Ca2 wave propagation between glial cells in an intact fluo-4. Mechanical stimulation of astrocyte somata evoked Ca2 waves that propagated through both

  7. Retinyl Ester Storage Particles (Retinosomes) from the Retinal Pigmented Epithelium Resemble Lipid Droplets in Other

    E-Print Network [OSTI]

    Palczewski, Krzysztof

    retinosomes are structures spe- cific to the eye or similar to lipid droplets in other organs functions such as nourishing and removing metabolic waste products, absorbing excess light, phagocytosis of photoreceptor fragments, and recycling the visual chro- mophore, 11-cis-retinal (2­6). Recycling of 11-cis

  8. Molecular mechanisms mediating retinal reactive gliosis following bone marrow mesenchymal stem cell (BM-MSC) transplantation

    E-Print Network [OSTI]

    Tassoni, Alessia; Gutteridge, Alex; Barber, Amanda C.; Osborne, Andrew; Martin, Keith R.

    2015-01-01T23:59:59.000Z

    found in vivo that intravitreal BM-MSC transplantation is associated with gliosis-mediated retinal folding, up-regulation of intermediate filaments and recruitment of macrophages. These responses were accompanied by significant JAK/STAT3 and MAPK (ERK1...

  9. Activation of retinal tyrosine hydroxylase: tolerance induced by chronic treatment with haloperidol does not modify response to light

    SciTech Connect (OSTI)

    Cohen, J.; Neff, N.H.

    1982-05-01T23:59:59.000Z

    A single dose of haloperidol administered to rats in the dark increases the activity of retinal tyrosine hydroxylase. The ability of haloperidol to activate the enzyme is diminished 24 hr after terminating 22 to 30 days of treatment with haloperidol. The retinal enzyme is also tolerant to activation by treatment with chlorpromazine. In contrast, exposure of the animals to light activates the enzyme to the same extent in chronic haloperidol-treated and control animals. Thus, chronic haloperidol treatment does not modify the ability of the retinal enzyme system to respond to the physiological stimulus, light. Apparently, activation of retinol tyrosine hydroxylase by haloperidol and light occurs by independent mechanisms.

  10. Journal of Environmental Protection, 2012, 3, 809-822 doi:10.4236/jep.2012.328096 Published Online August 2012 (http://www.SciRP.org/journal/jep)

    E-Print Network [OSTI]

    Mazumder, Asit

    August 2012 (http://www.SciRP.org/journal/jep) 809 Impacts of Land Use, Fertilizer and Manure Application of Biology, University of Victoria, Victoria, Canada; 2 Kamloops Range Research Station, Agriculture and Agri

  11. Modeling, Pattern Analysis and Feature-Based Retrieval on Retinal Images

    E-Print Network [OSTI]

    Ying, Huajun

    2012-07-16T23:59:59.000Z

    modeling techniques on the rotational contrast transform (RCT) of image pixels, we do a quantified reasoning of the transitional Figure 1: Proposed analytical framework on retinal image. 3 properties of vessel pixels from center-line vessel... visualization technique called daisy graph representation developed in our previous work [71] to approach the physical property of image pixel. Daisy graph representation results from the technique of rotational contrast transform (RCT) [71] of 21 image...

  12. Slow Feature Analysis on Retinal Waves Leads to V1 Complex Cells

    E-Print Network [OSTI]

    Wiskott, Laurenz

    Slow Feature Analysis on Retinal Waves Leads to V1 Complex Cells Sven Da¨hne1,2,3 *, Niko Wilbert2 such that it is best prepared for coding input from the natural world. Citation: Da¨hne S, Wilbert N, Wiskott L (2014 Received June 25, 2013; Accepted December 20, 2013; Published May 8, 2014 Copyright: ß 2014 Da¨hne et al

  13. High-resolution retinal imaging using adaptive optics and Fourier-domain optical coherence tomography

    DOE Patents [OSTI]

    Olivier, Scot S. (Livermore, CA); Werner, John S. (Davis, CA); Zawadzki, Robert J. (Sacramento, CA); Laut, Sophie P. (Pasedena, CA); Jones, Steven M. (Livermore, CA)

    2010-09-07T23:59:59.000Z

    This invention permits retinal images to be acquired at high speed and with unprecedented resolution in three dimensions (4.times.4.times.6 .mu.m). The instrument achieves high lateral resolution by using adaptive optics to correct optical aberrations of the human eye in real time. High axial resolution and high speed are made possible by the use of Fourier-domain optical coherence tomography. Using this system, we have demonstrated the ability to image microscopic blood vessels and the cone photoreceptor mosaic.

  14. Blood flow measurement and slow flow detection in retinal vessels with Joint Spectral and Time domain method in ultrahigh speed OCT

    E-Print Network [OSTI]

    Gorczynska, I.

    We present an application of the Joint Spectral and Time domain OCT (STdOCT) method for detection of wide range of flows in the retinal vessels. We utilized spectral/Fourier domain OCT (SOCT) technique for development of ...

  15. Retinal instrument

    SciTech Connect (OSTI)

    Britton, Charles L; D& #x27; Urso, Brian R; Chaum, Edward; Simpson, John T; Baba, Justin S; Ericson, M. Nance; Warmack, Robert J

    2013-04-23T23:59:59.000Z

    In one embodiment, the present invention provides a method of removing scar tissue from an eye that includes inserting a device including an array of micro-rods into an eye, wherein at least one glass micro-rod of the array of glass micro-rods includes a sharp feature; contacting a scar tissue with the array of micro-rods; and removing the array of micro-rods and the scar tissue from the eye. In another embodiment, the present invention provides a medical device for engaging a tissue including and an array of glass micro-rods, wherein at least one glass micro-rod of the array of glass micro-rods includes a sharp feature opposite a base of the array of glass micro-rods that is connected to the cannula, wherein the sharp feature of the at least one micro-rod is angled from a plane that is normal to a face of the base of the array of glass micro-rods.

  16. Retinal Ganglion

    E-Print Network [OSTI]

    This procedure also presents limitations, as the processing of visual .... that given two input signals x1(t) and x2(t) which produce corresponding outputs y1(t) and ...

  17. E-Print Network 3.0 - amaurosis protein aipl1 Sample Search Results

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    chaperones, RP2 and AIPL1. Molecular chaperone mediated protein... and protein folding in human disease, particularly retinal degeneration and neurodegeneration. We...

  18. Models of Type I X-ray Bursts from GS 1826-24: A Probe of rp-Process Hydrogen Burning

    E-Print Network [OSTI]

    Alexander Heger; Andrew Cumming; Duncan K. Galloway; Stanford E. Woosley

    2007-11-08T23:59:59.000Z

    The X-ray burster GS 1826-24 shows extremely regular Type I X-ray bursts whose energetics and recurrence times agree well with thermonuclear ignition models. We present calculations of sequences of burst lightcurves using multizone models which follow the rp-process nucleosynthesis with an extensive nuclear reaction network. The theoretical and observed burst lightcurves show remarkable agreement. The models naturally explain the slow ~5s rise and long ~100s tails of these bursts, as well as their dependence on mass accretion rate. This comparison provides further evidence for solar metallicity in the accreted material in this source, and constrains the distance to the source. The main difference is that the observed lightcurves do not show the distinct two-stage rise of the models. This may reflect the time for burning to spread over the stellar surface, or may indicate that our treatment of heat transport or nuclear physics needs to be revised. The trends in burst properties with accretion rate are well-reproduced by our spherically symmetric models which include chemical and thermal inertia from the ashes of previous bursts. Changes in the covering fraction of the accreted fuel are not required.

  19. Mass measurements in the vicinity of the rp-process and the nu p-process paths with JYFLTRAP and SHIPTRAP

    E-Print Network [OSTI]

    C. Weber; V. -V. Elomaa; R. Ferrer; C. Fröhlich; D. Ackermann; J. Äystö; G. Audi; L. Batist; K. Blaum; M. Block; A. Chaudhuri; M. Dworschak; S. Eliseev; T. Eronen; U. Hager; J. Hakala; F. Herfurth; F. P. Heßberger; S. Hofmann; A. Jokinen; A. Kankainen; H. -J. Kluge; K. Langanke; A. Martín; G. Martínez-Pinedo; M. Mazzocco; I. D. Moore; J. B. Neumayr; Yu. N. Novikov; H. Penttilä; W. R. Plaß; A. V. Popov; S. Rahaman; T. Rauscher; C. Rauth; J. Rissanen; D. Rodríguez; A. Saastamoinen; C. Scheidenberger; L. Schweikhard; D. M. Seliverstov; T. Sonoda; F. -K. Thielemann; P. G. Thirolf; G. K. Vorobjev

    2008-08-29T23:59:59.000Z

    The masses of very neutron-deficient nuclides close to the astrophysical rp- and nu p-process paths have been determined with the Penning trap facilities JYFLTRAP at JYFL/Jyv\\"askyl\\"a and SHIPTRAP at GSI/Darmstadt. Isotopes from yttrium (Z = 39) to palladium (Z = 46) have been produced in heavy-ion fusion-evaporation reactions. In total 21 nuclides were studied and almost half of the mass values were experimentally determined for the first time: 88Tc, 90-92Ru, 92-94Rh, and 94,95Pd. For the 95Pdm, (21/2^+) high-spin state, a first direct mass determination was performed. Relative mass uncertainties of typically $\\delta m / m = 5 \\times 10^{-8}$ were obtained. The impact of the new mass values has been studied in nu p-process nucleosynthesis calculations. The resulting reaction flow and the final abundances are compared to those obtained with the data of the Atomic Mass Evaluation 2003.

  20. Open Journal of Composite Materials, 2012, 2, 119-124 doi:10.4236/ojcm.2012.24014 Published Online October 2012 (http://www.SciRP.org/journal/ojcm)

    E-Print Network [OSTI]

    Liu, J. Ping

    October 2012 (http://www.SciRP.org/journal/ojcm) 119 Magnetic Properties Hard-Soft SmCo5-FeNi and SmCo5-Fe; revised June 27th , 2012; accepted July 8th , 2012 ABSTRACT Composites of SmCo5-FeNi and SmCo5-FeCo, hard-soft magnetic materials, have been synthesized via electroless plating of magnetically hard SmCo5 powder

  1. DOE FINAL TECHNICAL REPORT RP

    SciTech Connect (OSTI)

    RUSS PETERMAN

    2012-01-01T23:59:59.000Z

    The City of Georgetown Utility Systems (GUS) patnered with the private sector, the American Public Power Association (APPA) and Southwestern University to design, construct, test and monitor a solar co-generation system directly connected to the GUS electric distribution system. This report consists of the Primary Technical Report and 3 attachments.

  2. if020rp6.PDF

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOn AprilA group currentBradleyTable of Contents: AofIDAHO OPERATIONS OFFICE DURING THE

  3. Ethanol-induced Retinal Defects are Rescued by Retinoic Acid Supplement in Developing Zebrafish Pooja Muralidharan, Swapnalee Sarmah, James A. Marrs

    E-Print Network [OSTI]

    Zhou, Yaoqi

    Ethanol-induced Retinal Defects are Rescued by Retinoic Acid Supplement in Developing Zebrafish laboratory has used a zebrafish model for FASD that exposes embryos to ethanol during early development ranging from small eyes, underdeveloped optic nerve, and cataract. Zebrafish embryos exposed to ethanol

  4. MRP4 knockdown enhances migration, suppresses apoptosis, and produces aggregated morphology in human retinal vascular endothelial cells

    SciTech Connect (OSTI)

    Tagami, Mizuki [Department of Surgery Related, Division of Ophthalmology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017 (Japan)] [Department of Surgery Related, Division of Ophthalmology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017 (Japan); Kusuhara, Sentaro, E-mail: kusu@med.kobe-u.ac.jp [Department of Surgery Related, Division of Ophthalmology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017 (Japan)] [Department of Surgery Related, Division of Ophthalmology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017 (Japan); Imai, Hisanori [Department of Surgery Related, Division of Ophthalmology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017 (Japan)] [Department of Surgery Related, Division of Ophthalmology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017 (Japan); Uemura, Akiyoshi [Department of Surgery Related, Division of Ophthalmology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017 (Japan) [Department of Surgery Related, Division of Ophthalmology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017 (Japan); Department of Vascular Biology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017 (Japan); Honda, Shigeru; Tsukahara, Yasutomo; Negi, Akira [Department of Surgery Related, Division of Ophthalmology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017 (Japan)] [Department of Surgery Related, Division of Ophthalmology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017 (Japan)

    2010-10-01T23:59:59.000Z

    Research highlights: {yields} Exogenous VEGF decreases MRP4 expression in a dose-dependent manner. {yields} MRP4 knockdown leads to enhanced cell migration. {yields} MRP4 knockdown suppresses caspase-3-mediated cell apoptosis. {yields} MRP4 knockdown produces cell assembly and cell aggregation. -- Abstract: The multidrug resistance protein (MRP) MRP4/ABCC4 is an ATP-binding cassette transporter that actively effluxes endogenous and xenobiotic substrates out of cells. In the rodent retina, Mrp4 mRNA and protein are exclusively expressed in vascular endothelial cells, but the angiogenic properties of Mrp4 are poorly understood so far. This study aims to explore the angiogenic properties of MRP4 in human retinal microvascular endothelial cells (HRECs) utilizing the RNA interference (RNAi) technique. MRP4 expression was decreased at the mRNA and protein levels after stimulation with exogenous vascular endothelial growth factor in a dose-dependent manner. RNAi-mediated MRP4 knockdown in HRECs do not affect cell proliferation but enhances cell migration. Moreover, cell apoptosis induced by serum starvation was less prominent in MRP4 siRNA-treated HRECs as compared to control siRNA-treated HRECs. In a Matrigel-based tube-formation assay, although MRP4 knockdown did not lead to a significant change in the total tube length, MRP4 siRNA-treated HRECs assembled and aggregated into a massive tube-like structure, which was not observed in control siRNA-treated HRECs. These results suggest that MRP4 is uniquely involved in retinal angiogenesis.

  5. Networking RP @ DISI Fabrizio Granelli, Lab Coordinator

    E-Print Network [OSTI]

    Granelli, Fabrizio

    Christian FACCHINI PhD Student Troung Huong THU PhD Student Olga ZADEDYURINA PhD Student #12;Dipartimento di-TRUST (Remote EnTrusting by RUn-time Software auThentication) WOMEN (Wireless 802.16 Multi-antenna Mesh Networks

  6. Bryant fall 2010 FCP H I L A N T H R O P Y I N A C T I O N FA L L/WI NTER2011ABRyA NTUN IvE RsITyREsoURcEFo RP Ro FEssIoNALsUccEss

    E-Print Network [OSTI]

    Blais, Brian

    Bryant fall 2010 FCP H I L A N T H R O P Y I N A C T I O N FA L L/WI NTER2011ABRyA NTUN IvE RsITyREsoURcEFo RP Ro FEssIoNALsUccEss #12;1 President's Message 2 VisiOn 2020 Bryant charts a bold course's success. 12 inVesting in tHe neXt generatiOn Helping deserving students make their hopes come true, Bryant

  7. L e x ica l M o rp h o lo g y a n d th e T w o O rth o g ra p h ic W illia m B a d e c k e r, B re n d a R a p p

    E-Print Network [OSTI]

    Caramazza, Alfonso

    L e x ica l M o rp h o lo g y a n d th e T w o O rth o g ra p h ic R o u tes W illia m B a d e c k e r, B re n d a R a p p Jo h n s H op k ins U n iv ersity , B altim o re, U S A A lfo n so C a ra m a z z a H a rva rd U n iversity, C a m b rid g e, U S A W e r e p o r t a c a s e o f d y s g r a p h

  8. TGF-{beta}-stimulated aberrant expression of class III {beta}-tubulin via the ERK signaling pathway in cultured retinal pigment epithelial cells

    SciTech Connect (OSTI)

    Chung, Eun Jee [Department of Ophthalmology, National Health Insurance Corporation Ilsan Hospital, Gyeonggi-do (Korea, Republic of)] [Department of Ophthalmology, National Health Insurance Corporation Ilsan Hospital, Gyeonggi-do (Korea, Republic of); Chun, Ji Na; Jung, Sun-Ah [Konyang University Myunggok Medical Research Institute, Kim's Eye Hospital, Konyang University College of Medicine, Seoul (Korea, Republic of)] [Konyang University Myunggok Medical Research Institute, Kim's Eye Hospital, Konyang University College of Medicine, Seoul (Korea, Republic of); Cho, Jin Won [Department of Biology, Yonsei University, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-749 (Korea, Republic of)] [Department of Biology, Yonsei University, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-749 (Korea, Republic of); Lee, Joon H., E-mail: joonhlee@konyang.ac.kr [Konyang University Myunggok Medical Research Institute, Kim's Eye Hospital, Konyang University College of Medicine, Seoul (Korea, Republic of)

    2011-11-18T23:59:59.000Z

    Highlights: Black-Right-Pointing-Pointer TGF-{beta} induces aberrant expression of {beta}III in RPE cells via the ERK pathway. Black-Right-Pointing-Pointer TGF-{beta} increases O-GlcNAc modification of {beta}III in RPE cells. Black-Right-Pointing-Pointer Mature RPE cells have the capacity to express a neuron-associated gene by TGF-{beta}. -- Abstract: The class III {beta}-tubulin isotype ({beta}{sub III}) is expressed exclusively by neurons within the normal human retina and is not present in normal retinal pigment epithelial (RPE) cells in situ or in the early phase of primary cultures. However, aberrant expression of class III {beta}-tubulin has been observed in passaged RPE cells and RPE cells with dedifferentiated morphology in pathologic epiretinal membranes from idiopathic macular pucker, proliferative vitreoretinopathy (PVR) and proliferative diabetic retinopathy (PDR). Transforming growth factor-{beta} (TGF-{beta}) has been implicated in dedifferentiation of RPE cells and has a critical role in the development of proliferative vitreoretinal diseases. Here, we investigated the potential effects of TGF-{beta} on the aberrant expression of class III {beta}-tubulin and the intracellular signaling pathway mediating these changes. TGF-{beta}-induced aberrant expression and O-linked-{beta}-N-acetylglucosamine (O-GlcNac) modification of class III {beta}-tubulin in cultured RPE cells as determined using Western blotting, RT-PCR and immunocytochemistry. TGF-{beta} also stimulated phosphorylation of ERK. TGF-{beta}-induced aberrant expression of class III {beta}-tubulin was significantly reduced by pretreatment with U0126, an inhibitor of ERK phosphorylation. Our findings indicate that TGF-{beta} stimulated aberrant expression of class III {beta}-tubulin via activation of the ERK signaling pathway. These data demonstrate that mature RPE cells have the capacity to express a neuron-associated gene in response to TGF-{beta} stimulation and provide useful information towards understanding the pathogenesis of proliferative vitreoretinal diseases.

  9. Prurigo pigmentosa: Report of two cases in the United States and review of the literature

    E-Print Network [OSTI]

    Whang, Talley; Kirkorian, A Yasmine; Krishtul, Anna; Phelps, Robert; Shim-Chang, Helen

    2011-01-01T23:59:59.000Z

    in association with helicobacter pylori infection in aatopy [ 13 , 14 ], Helicobacter pylori infection [ 15 ],

  10. INSTITUT NATIONAL POLYTECHNIQUE DE LORRAINE ECOLE DOCTORALE RP2E

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    DES PROCEDES D'OXYDATION DES HYDROCARBURES Soutenue publiquement le 29 mars 2006 devant la Commission PROCEDES D'OXYDATION D'HYDROCARBURES 7 1. Problèmes de sécurité dans l'industrie des procédés d'oxydation d'hydrocarbures hydrocarbures 11 2. Généralités sur les explosions de gaz 14 2.1. Combustion et explosion 14 2.1.1. Définition

  11. IDC RP2 & 3 US Industry Standard Cost Estimate Summary.

    SciTech Connect (OSTI)

    Harris, James M.; Huelskamp, Robert M.

    2015-01-01T23:59:59.000Z

    Sandia National Laboratories has prepared a ROM cost estimate for budgetary planning for the IDC Reengineering Phase 2 & 3 effort, using a commercial software cost estimation tool calibrated to US industry performance parameters. This is not a cost estimate for Sandia to perform the project. This report provides the ROM cost estimate and describes the methodology, assumptions, and cost model details used to create the ROM cost estimate. ROM Cost Estimate Disclaimer Contained herein is a Rough Order of Magnitude (ROM) cost estimate that has been provided to enable initial planning for this proposed project. This ROM cost estimate is submitted to facilitate informal discussions in relation to this project and is NOT intended to commit Sandia National Laboratories (Sandia) or its resources. Furthermore, as a Federally Funded Research and Development Center (FFRDC), Sandia must be compliant with the Anti-Deficiency Act and operate on a full-cost recovery basis. Therefore, while Sandia, in conjunction with the Sponsor, will use best judgment to execute work and to address the highest risks and most important issues in order to effectively manage within cost constraints, this ROM estimate and any subsequent approved cost estimates are on a 'full-cost recovery' basis. Thus, work can neither commence nor continue unless adequate funding has been accepted and certified by DOE.

  12. GVB RP: A Reliable MCSCF Wave Function for Large Systems

    E-Print Network [OSTI]

    Goddard III, William A.

    DURIP; BP Chemical; ARO; Exxon; Seiko-Epson; Owens Corning; Asahi Chemical, Saudi Aramco; Beckman Institute

  13. SRNL-RP-2009-00869 BIOLOGY, DAMAGE,

    E-Print Network [OSTI]

    Ditchkoff, Steve

    . Lehr Brisbin, Jr. Editors Savannah River National Laboratory Aiken, South Carolina 2009 #12;ii University of Georgia - Savannah River Ecology Laboratory #12;Wild Pigs 357 Wild Pig Management Case Study This document was prepared by Savannah River Nuclear Solutions, LLC, under contract number DE-AC09-08SR22470

  14. SRO-N E RP-12 ,/-:.:;:"Yj$~~-'

    E-Print Network [OSTI]

    Georgia, University of

    privately owned rights. A PUB LICATION OF DOE'S SAVANNAH RIVER PLANT NATIONAL ENVIRONMENTAL RESEARCH PARK - AUGUST, 1983 Copies may be obtained from Savannah River Ecology Laboratory #12;-. -. THE FISHES OF THE SAVANNAH RIVER PLANT: NATIONAL ENVIRONMENTAL RESEARCH PARK by David H. Bennett} Savannah River Ecology

  15. SRNL-RP-2009-00869 BIOLOGY, DAMAGE,

    E-Print Network [OSTI]

    Ditchkoff, Steve

    . Lehr Brisbin, Jr. Editors Savannah River National Laboratory Aiken, South Carolina 2009 #12;ii University, Auburn, Alabama 36849 (SSD) Savannah River National Laboratory, Savannah River Nuclear Solutions University of Georgia - Savannah River Ecology Laboratory #12;Wild Pigs 105 Biology of Wild Pigs: Wild Pig

  16. References: Allan, RP, J Clim 22 (11) p3127 (2009)

    E-Print Network [OSTI]

    2009-01-01T23:59:59.000Z

    Deseasonalized anomalies of atmospheric longwave radiative cooling from reanalyses, climate models and satellite in the observing system and the reanalysis fields contribute to this discrepancy (below). descent ascentFrequency of Precipitation · Earth's radiation balance provides a powerful constraint upon future changes in precipitation

  17. RP Global Spain S A Minicentrales | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directedAnnualProperty Edit with form History Facebook iconQuito,Jump to: navigation,REpower

  18. CHAPTER: In-Situ Characterization of Stimulating Microelectrode Arrays: Study of an Idealized Structure Based on Argus II Retinal implantsBOOK TITLE: Implantable Neural Prostheses 2: Techniques and Engineering Approaches, D.M. Zhou and E. Greenbaum, Eds., Springer, NY 2009

    SciTech Connect (OSTI)

    Greenbaum, Elias [ORNL; Sanders, Charlene A [ORNL; Kandagor, Vincent [ORNL

    2010-01-01T23:59:59.000Z

    The development of a retinal prosthesis for artificial sight includes a study of the factors affecting the structural and functional stability of chronically implanted microelectrode arrays. Although neuron depolarization and propagation of electrical signals have been studied for nearly a century, the use of multielectrode stimulation as a proposed therapy to treat blindness is a frontier area of modern ophthalmology research. Mapping and characterizing the topographic information contained in the electric field potentials and understanding how this information is transmitted and interpreted in the visual cortex is still very much a work in progress. In order to characterize the electrical field patterns generated by the device, an in vitro prototype that mimics several of the physical and chemical parameters of the in vivo visual implant device was fabricated. We carried out multiple electrical measurements in a model 'eye,' beginning with a single electrode, followed by a 9-electrode array structure, both idealized components based on the Argus II retinal implants. Correlating the information contained in the topographic features of the electric fields with psychophysical testing in patients may help reduce the time required for patients to convert the electrical patterns into graphic signals.

  19. REVERSIBLE THERMOSENSITIVE GLUE FOR RETINAL IMPLANTS

    E-Print Network [OSTI]

    Meng, Ellis

    . Methods: Polyimide (50 m), parylene C [poly(monochloro-p-xylylene)] (20 m), and poly(dimethyl siloxane three types of base materials: polyimide, parylene C [poly(monochloro-p-xylylene)], and poly- (dimethyl of the epiretinal electrode for epiretinal stimulation. Polyimide was prepared as 50 m thick films, parylene as 20

  20. Progress in Retinal and Eye Research, In Press Retinal Connectomics: Towards Complete, Accurate Networks

    E-Print Network [OSTI]

    Marc, Robert E.

    den Heuvel and Sporns, 2011), mesoscale optical studies of connections between defined brain regions

  1. Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidance 

    E-Print Network [OSTI]

    Manuel, M.; Pratt, T.; Liu, M.; Jeffery, G.; Price, D. J.

    errors in intraretinal navigation by RGC axons, a decrease in the number of RGC axons reaching the thalamus and an increase in the proportion of ipsilateral projections among those RGC axons that do reach the thalamus. A survey of embryos with different...

  2. A Coupled Airflow-and-Energy Simulation Program for Indoor Thermal Environment Studies (RP-927)

    E-Print Network [OSTI]

    Chen, Qingyan "Yan"

    for the design of radiative, convective, and hybrid heating and cooling systems. Keywords: Airflow, Air for thermal comfort (ASHRAE 1992). In an indoor space with radiative, convective, and hybrid heating with convective, radiative, and hybrid heating and cooling systems. In the past few years, many investigations

  3. Systematic study of person-to-person contaminant transport in mechanically ventilated spaces (RP-1458)

    E-Print Network [OSTI]

    Chen, Qingyan "Yan"

    at the inlets Tout the temperatures at the exhaust C* the normalized SF6 concentration C the local SF6 concentration Cin the SF6 concentration at the inlets Cout the SF6 concentration at the exhaust #12

  4. 2012 ASHRAE 1061 This paper is based on findings resulting from ASHRAE Research Project RP-1356.

    E-Print Network [OSTI]

    Ghajar, Afshin J.

    . ABSTRACT Mechanical pipe insulation systems are installed around cold cylindrical surfaces, such as chilled accurate prediction of the pipe insulation actual thermal conductivity is needed for the design thermal conductivity were developed based on insulation specimen average temperature and wall thicknesses

  5. CBFO:AMO:RP:GS:05-0217:UFC 5486.00 Department of Energy

    E-Print Network [OSTI]

    not be considered high-level waste because they were not produced directly in reprocessing of spent nuclear fuel than 20 years. Likewise, we do not believe that the basin waste is spent nuclear fuel because Certification Compliance Manager Enclosures cc: w/enclosure B. Forinash, EPA * ED S. White, EPA ED C. Byrum, EPA

  6. Discharge characteristics of silver vanadium oxide cathodes R.P. RAMASAMY1

    E-Print Network [OSTI]

    Popov, Branko N.

    2 and B.N. POPOV1, * 1 Department of Chemical Engineering, University of South Carolina, Columbia+ intercalated in LixAg2V4O11) with the concurrent reduction of Ag+ to Ag0 , which consti- tutes 30

  7. WSRC-RP-2003-00276 Department of Energy Office of Science and Technology

    E-Print Network [OSTI]

    Hazen, Terry

    -30, 2003 Technical Assistance Team / Authors: Brian B. Looney, Savannah River Technology Center (chair) Terry C. Hazen, Lawrence Berkeley National Laboratory David L. Eaton, Idaho National Environment RIVER 740 ELE VAT ION (MS L) 750 760 770 780 790 800 810 KC94-195 SHALE/SANDY SHALE (PLEASANTON) CLAYEY

  8. Qualification of Fan Generated Duct Rumble Noise: Part 1: Test Facility(RP 1219)

    E-Print Network [OSTI]

    Kading, J.; Mann, A.; Pate, M.B.

    the transition duct from break in noise from the fan room. The fiberglass insulation on the inside of the box was suspended against the MDF in order to limit any vibration damping that might occur if the insula- tion touched the duct. The duct work continued... mounted to a base. The mounting base was a double steel strut that held the fan and motor assemble together. The mounting base had six vibration isolation springs that it supported by. The four corner springs were 800 lb, 1” isolation springs, the middle...

  9. Qualification of Fan Generated Duct Rumble Noise: Part 2: Results (RP 1219)

    E-Print Network [OSTI]

    Kading, J.; Mann, A.; Pate, M.B.

    represented the closest to the ideal configuration. REMOVING TONES In the cases where the sound levels were low, tones enter- ing the sound measurements from the fan and motor vibration were a concern. This issue was remedied by removing the tones from... is not permitted without ASHRAE’s prior written permission. ESL-PA-08-06-09 Published in ASHRAE Transactions Vol. 114, Part 2 36 ASHRAE Transactions 3. Redesign the fan and motor support structure to reduce vibration. 4. Study additional fans and select fans...

  10. Microsoft Word - 2015-03-17_FINALRev0_SRNL-RP-2014-01198c

    Office of Environmental Management (EM)

    Strain Curves for a drum obtained from LANL. Figure D-11. Tested Drum Lid Engineering Stress-Percent Strain Curves for a drum obtained from LANL. Analysis Approaches...

  11. Texas Transportation Institute, Agency 727 Energy Management and Conservation Plan (RP-49)

    E-Print Network [OSTI]

    its in-house preventive maintenance program. TTI is committed to minimizing fuel use in its fleet at their peak efficiency, TTI maintains an in-house preventive maintenance program for all fleet vehicles. Preventive maintenance procedures as recommended by the SFVMP as well as vehicle manufacturers

  12. Texas Transportation Institute, Agency 727 Energy Management and Conservation Plan (RP-49)

    E-Print Network [OSTI]

    -efficiency awareness and procedures to its employees and continues to improve its in-house preventive maintenance-house preventive maintenance program for all fleet vehicles. Preventive maintenance procedures as recommended maintenance greatly contributes in keeping vehicles at their peak efficiency, TTI maintains an in

  13. Radiological Survey Results for the R.P. Adams Company Property, Tonawanda, New York (TNY003)

    SciTech Connect (OSTI)

    Carrier, R.F.; McKenzie, S.P.; Uziel, M.S.

    1998-11-01T23:59:59.000Z

    At the request of the U.S. Department of Energy (DOE), a team horn Oak Ridge National Laboratory conducted a radiological survey of property belonging to the R P. Adarns Company, Inc., Tonawanda, New York. The survqy was performed in November 1995 and May and July 1996. The P-e of tie SUIWY was to determine if radioactive residuals had migrated, or been re&stribu@ from the former Linde property to the south onto the R P. Adams property. The Linde Air Products Division of Union Carbide Corporation, Toni~w~da, New York, had used radioactive materials at that location for work performed under government contract born 1942 through 1948. The survey was performed in response to Formerly Utilized Sites Remedial Action Program (FUSRAP) requirements. These requirements dictate that the radiological status of certain vicinity properties shall be assessed and docw.nented according to prescribed procedures prior to certification of the property for release for unrestricted use. Such release can only be granted if the property is found to be within current applicable authorized limits. The survey included a gamma scan of accessible areas in both the developed and the undeveloped portions of the property and the collection and radionuclide analysis of soil samples. A comparison of these data to the current DOE guidelines shows that all radionuclide concentrations and radioactivity levels found on the property are below the current guidelines. Therefore, this property should not be included in the FUSRAP program for remediation. xi

  14. Static Pressure Losses in 6 in., 8 in., and 10 in. Nonmetallic Flexible Duct (RP-1333)

    E-Print Network [OSTI]

    Weaver, K.; Culp, C.H.

    Reproduced with permission of the copyright owner. Further reproduction prohibited without permission. Static Pressure Losses in Nonmetallic Flexible Duct Weaver, Kevin;Culp, Charles ASHRAE Transactions; 2007; 113, ProQuest pg. 400 Reproduced...

  15. Solution NMR structure of the ribosomal protein RP-L35Ae from...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    subunits each comprised of dozens of proteins and RNA molecules several-hundred nucleotides in length. However, the functions of many of the individual protomers within the...

  16. Low-lying levels in Cu-57 and the rp process

    E-Print Network [OSTI]

    Zhou, XG; Dejbakhsh, H.; Gagliardi, Carl A.; Jiang, J.; Trache, L.; Tribble, Robert E.

    1996-01-01T23:59:59.000Z

    . In particular, a comparison of the low-lying levels of 57Cu with the well-determined excited states of its mirror nucleus 57Ni is important for studying the charge symmetry of the nucleus. The structure of 57Cu also plays a key role in the nucleo- synthesis...

  17. An example of verification, validation, and reporting of indoor environment CFD analyses (RP-1133)

    E-Print Network [OSTI]

    Chen, Qingyan "Yan"

    through an example of indoor environment modeling (an office with mechanical displacement ventilation similar procedure. The emphasis of the verification and validation is problem dependent. The computational ventilation systems and the development of control strategies require detailed knowledge of airflow

  18. DE-RP05-08OR23286 SOLICITATION, OFFER AND AWARD 4. TYPE OF SOLICITATION

    Office of Environmental Management (EM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742 33 1112011AT&T,Office of Policy, OAPM | Department ofCommunications3 DATE:Award No. 2.OTHER

  19. Golden Reading Room: Request for Proposals (RFP) Number DE-RP36-07GO97036 |

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742Energy ChinaofSchaefer To: CongestionDevelopment of a downholeReactorsgoal andLast

  20. Microsoft Word - 2015-03-17_FINALRev0_SRNL-RP-2014-01198c

    Office of Environmental Management (EM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742 33 111 1,613 122Commercial602 1,39732onMake Your NextHow EM Does Business ThomasTechnical Assessment

  1. Savannah River Site Land Use Plan - May, 2013 i SRNS-RP-2013-00162

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclearHomeland andEffects andFundedUniversityEnergy

  2. Request for Proposals (RFP) Number DE-RP36-07GO97036: Alliance Prime

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onYouTube YouTube Note: Since the.pdfBreakingMay 2015 < prevQuickEnergyfor a ManufacturingIssues |RequestContract

  3. Alpha Emission Near 100Sn and the Termination of the rp Process

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office511041cloth DocumentationProducts (VAP) VAP7-0973ManagedStrategic|AljazeeraO S o'ware a nd D ataAlpha

  4. Microsoft Word - 2015-03-17_FINALRev0_SRNL-RP-2014-01198c

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Science (SC)Integrated Codes |IsLove Your HomeOverviewCleanupShipping Form3 A LCF U serSAVE

  5. Microsoft PowerPoint - NA-RP_Public_Workshop_April-2013.ppt

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville PowerCherries 82981-1cnHighand RetrievalsFinalModule8.pptStates A ComparisonMorgantown Site

  6. Effects of hydroquinone on retinal and vascular cells in vitro

    E-Print Network [OSTI]

    Kenney, Cristina M.; Kuppermann, Baruch D.; Patil, Jayaprakash A.; Seigel, Gail M.; Sharma, Ashish; Gramajo, Ana L.

    2012-01-01T23:59:59.000Z

    Ames BN, Cotman CW, et al. Acrolein, a toxicant in cigarettetoxicants, including acrolein that damages mitochondrial

  7. Neuronal Circuitry of the Local Edge Detector Retinal Ganglion Cell

    E-Print Network [OSTI]

    Russell, Thomas Lee

    2010-01-01T23:59:59.000Z

    Rapid Narrow Luminance Changes……………………………………………………………………12responds selectively to luminance edges. But what neuronalto show that selectivity to luminance edges in the LED is

  8. Developmental Mechanisms for Retinal Degeneration in the Blind Cavefish

    E-Print Network [OSTI]

    Jeffery, William R.

    , and Vax1, together with the differen- tiation marker GAD65. We show that eye development is retarded in CF; eye; proliferation; cell death; Shh; Fgf8; Pax6; LIM-homeodomain; Vax1; GABA; teleost; fish Vertebrate

  9. Supplementary Information Primary amines protect against retinal degeneration in

    E-Print Network [OSTI]

    Palczewski, Krzysztof

    µm column, linear gradient of acetonitrile in water (0­ 100% acetonitrile over 20 min at a flow rate) in a linear gradient of acetonitrile in water (80 ­ 100% acetonitrile over 20 min at a flow rate of 1.5 ml/min). Both solvents contained 0.05% trifluoroacetic acid (TFA). HPLC elution: 9.0 min. UV/Vis (acetonitrile

  10. Identifying the Atomic Structure and Orientation of Supported Nanometersize D. Lovall, R.P. Andres \\Lambda and R. Reifenberger

    E-Print Network [OSTI]

    clusters. These results indicate that future molecu­ lar dynamic simulations of cluster structure and dynam the stability of the electron current emitted from a supported cluster in the presence of a high electric field

  11. Compilation of Diversity Factors and Schedules for Energy and Cooling Load Calculations, ASHRAE Research Project 1093-RP, Final Report

    E-Print Network [OSTI]

    Abushakra, B.; Sreshthaputra, A.; Haberl, J. S.; Claridge, D. E.

    2001-01-01T23:59:59.000Z

    of the diversity factor calculations are applied to the data collected for this project. The buildings analyzed for this report consisted of office buildings monitored by the ESL, and office buildings provided by the LBNL....

  12. June 4, 2009 11:38 WSPC/INSTRUCTION FILE ijfcsRP International Journal of Foundations of Computer Science

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    , FRANCE OLGA KOUCHNARENKO INRIA-CASSIS LIFC, Université de Franche-Comté, 16 route de Gray, 25000 Besançon of software systems is one of the most challenging research problems in computer aided verification

  13. RHUL MasteRpLan 2014 pLanning Design anD access stateMent

    E-Print Network [OSTI]

    Sheldon, Nathan D.

    and visual impact overview 9.6 Flood risk and drainage overview 9.7 Geo-environmental overview 9.8 Air and new build to improve the way that space is used, and the environmental impact and cost of our.2 Justification for the proposed development 3.3 Town planning history 3.4 Town planning policy overview 3.5 Site

  14. Applied Mathematical Sciences, Vol. 3, 2009, no. 54, 2703 -2706 The Limit of the Statistic R/P in Models

    E-Print Network [OSTI]

    Stark, Dudley

    to predict that the peak of oil production in the U.S.A. would occur between 1965 and 1970. Oil produc- tion for the U.S.A actually peaked in 1970. In Hubbert's analysis the profile for oil production is approximated/P in Models of Oil Discovery and Production Dudley Stark School of Mathematical Sciences Queen Mary

  15. Pressure Losses in 12”, 15” and 16” Non-Metallic Flexible Ducts with Compression and Sag (RP-1333)

    E-Print Network [OSTI]

    Culp, C.H.; Cantrill, D.

    . This study contains the measure- ments and calculated parameters from 12” (305 mm), 14” (356 mm) and 16” (406 mm) non-metallic flexible duct with compression and sag between 24” (610 mm) joists. Prior measurements of pressure drop for flexible ducts were... pressure losses which are 2 to 13 times higher than sheetmetal ducts. Ugursal and Culp (2007) calculated pressure loss using computational fluid dynamics (CFD) (Fluent, 2004). Their results showed agreement with fully stretched flexible duct and 30...

  16. Mitochondrial DNA haplogroups confer differences in risk for age-related macular degeneration: a case control study

    E-Print Network [OSTI]

    2013-01-01T23:59:59.000Z

    may change the retinal bioenergetics and play a significantmay change retinal bioenergetics and energy production

  17. FinalTechnicalReport_15U5O2I-11_RPSEA.docx

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    API RP 2INT MET (Central Gulf of Mexico) 1yr API RP 2INT MET 100yr API RP 2INT MET 1000yr API RP 2INT MET Fatigue Spectrum JONSWAP Gamma 1.0 Seastates Distribution Reference...

  18. Chapter 3. Terms and Conditions of Employment RP-59 Self-Insurance shall promptly notify the University's Director of Risk Management

    E-Print Network [OSTI]

    Farritor, Shane

    the University's Director of Risk Management of: 1) any occurrence the commissioned law enforcement officer has Management to be effective. (c) The University's Director of Risk Management shall make a decision on any claim for benefits promptly, and not later than thirty (30) days after the Director of Risk Management

  19. Applied Mathematics, 2011, 2, 541-550 doi:10.4236/am.2011.25071 Published Online May 2011 (http://www.SciRP.org/journal/am)

    E-Print Network [OSTI]

    Fadimba, Koffi B.

    Equation, Immiscible Two-Phase Flow, Regularization, Phase Mobility. 1. Introduction Consider the coupled nonlinear problem (1), with , which arises from modeling incompre- ssible two-phase immiscible (water/oil Darcy's velocity for the two-phase flow, f is the fractional flow function, S the saturation

  20. Teaching Bibliography Updated 6/04 Hesketh, R.P., Howat, C.S., and Dixon, D.S., editors, 2000. Chemical

    E-Print Network [OSTI]

    Howat, Colin S. "Chip"

    't Students Learn What I Teach? Department of Chemical & Petroleum Engineering Graduate Seminar, University of Chemical and Petroleum Engineering Graduate Seminar, University of Kansas, Lawrence, Kansas. Howat, C, 2000. Chemical Engineering Education in the New Millenium: Topical Conference Proceedings, AIChE Annual

  1. L3:THM.CFD.P5.02 J.N. Shadid, T.M. Smith, R.P. Pawlowski, E. C. Cyr,

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville PowerCherries 82981-1cnHigh SchoolIn12electron beamJoin2015JustKateKent52 J.N. Shadid, T.M. Smith,

  2. Non-Invasive Detection of Early Retinal Neuronal Degeneration by Ultrahigh Resolution Optical Coherence

    E-Print Network [OSTI]

    Martin, Ralph R.

    Coherence Tomography Debbie Tudor1 , Vedran Kajic´4 , Sara Rey3 , Irina Erchova1,3 , Boris Povazay4 , Bernd Hofer4 , Kate A. Powell3 , David Marshall2 , Paul L. Rosin2 , Wolfgang Drexler4 , James E. Morgan1,5 * 1

  3. A novel method for comparative analysis of retinal specialization traits from topographic maps

    E-Print Network [OSTI]

    Johnsen, Sönke

    , The Univ. of Western Australia, Crawley, WA, Australia Olaf R. P. Bininda-Emonds $ AG Systematik, The Univ. of Western Australia, Crawley, WA, Australia Esteban Fern ´andez-Juricic $Dept. of Biological of the brain. Photoreceptor cells are responsible for absorbing light energy or photons and transforming

  4. Enhanced visualization of retinal pathologies with ultrahigh resolution optical coherence tomography

    E-Print Network [OSTI]

    Ko, Tony Hong-Tyng, 1975-

    2005-01-01T23:59:59.000Z

    Current clinical practice calls for the development of techniques to diagnose diseases in its early stages, when treatment is most effective and significant irreversible damage can either be prevented or delayed. Optical ...

  5. Characterization of RPGR Variants and Their Role in Inherited Retinal Degeneration

    E-Print Network [OSTI]

    Wright, Rachel

    2012-10-19T23:59:59.000Z

    a gene between CYBB and OTC in Xp21.1 with 19 constitutive exons spanning 60kb of genomic DNA. The locus encodes a ubiquitously expressed protein, hereafter identified as RPGRex1-19, with a predicted molecular mass of approximately 90k... domains between the RCC1-homologous domain and ORF15 maintain a physiological role in the retina (28). Interestingly, four other known mutations within the RCC1- homologous domain (G173R; 786-787delTG; C469+1G>T, intron 5; c.619+9del, intron 6), result...

  6. 2001 Special issue ONOFF retinal ganglion cells temporally encode OFF/ON sequence

    E-Print Network [OSTI]

    Uchiyama, Hiroyuki

    ; Innisfree, UK). A light-emitting diode (LED; lp 590 nm) was positioned in the center of the receptive ®elds

  7. Retinal imaging tool for assessment of the parapapillary atrophy and the optic disc 

    E-Print Network [OSTI]

    Lu, Cheng-Kai

    2012-11-29T23:59:59.000Z

    Ophthalmic diseases such as glaucoma are associated with progressive changes in the structure of the optic disc (OD) and parapapillary atrophy (PPA). These structural changes may therefore have relevance to other systemic ...

  8. Laura Frishman, Professor, M.S., Ph.D., University of Pittsburgh. Retinal physiology;

    E-Print Network [OSTI]

    Glasser, Adrian

    in glaucoma, animal and human psychophysics, studies of sensory effects of early abnormal visual experience development, primates model of glaucoma. Michael Twa, Assistant Professor, O.D., UC Berkeley, Ph.D., Ohio State University. Clinical and experimental evaluation of the mechanisms of glaucomatous optic

  9. Involvement of All-trans-retinal in Acute Light-induced Retinopathy of Mice*S

    E-Print Network [OSTI]

    Palczewski, Krzysztof

    damage in humans and experimental ani- mals, but the mechanism(s) remain unclear. We investigated whether, Cleveland, Ohio 44106 Exposure to bright light can cause visual dysfunction and ret- inal photoreceptor­7) can accumulate as a consequence of aging (8). Under experimental conditions, these compounds can

  10. Neural stem cell differentiation in collagen scaffolds for retinal tissue engineering

    E-Print Network [OSTI]

    Ueda, Erica (Erica Ann)

    2008-01-01T23:59:59.000Z

    Rat neural stem cells (NSCs) were cultured in monolayer or in porous collagen scaffolds and exposed to neurogenic or non-neurogenic medium to determine the effects on neural differentiation and neurite growth. Nestin, ...

  11. Blood vessel detection in retinal images and its application in diabetic retinopathy screening

    E-Print Network [OSTI]

    Zhang, Ming

    2009-05-15T23:59:59.000Z

    transform (RCT) algorithm, which converts the intensity information in spatial domain to a high dimensional radial contrast domain. Different feature descriptors are designed to improve the speed, sensitivity, and expandability of the vessel detection system...

  12. THE IMPACT OF PULSE DURATION AND BURN GRADE ON SIZE OF RETINAL

    E-Print Network [OSTI]

    Palanker, Daniel

    , Federal University of Sao Paulo, Sao Paulo, Brazil; and §OptiMedica Corporation, Santa Clara, California. Palanker and M. Blumenkranz hold a Stanford University patent on patterned scanning laser photocoagulation

  13. Transcriptomic Analysis of Human Retinal Detachment Reveals Both Inflammatory Response and Photoreceptor

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    , De´partement d'Ophtalmologie, Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France, 5 management remains to this day exclusively surgical. We have used surgical specimens to perform

  14. Magnetic Resonance Imaging Indicates Decreased Choroidal and Retinal Blood Flow in the DBA/2J Mouse

    E-Print Network [OSTI]

    Duong, Timothy Q.

    proteins: tyrosinase-related protein 1 (Tyrp1), which causes iris stromal atrophy,6 and glycoprotein

  15. Novel Measures Of Retinal Health And Their Inter- relationships In Early Diabetes

    E-Print Network [OSTI]

    Dhamdhere, Kavita P.

    2012-01-01T23:59:59.000Z

    retinopathy. Curr. Diabetes Rev. 2, 71-98. 7. Wolter, J.sensitive color vision in patients with type I diabetes.Diabetes Care 10, 777-781. 9. Karen Holopigian, Vivienne C.

  16. Retinal microvascular abnormalities and cognitive function in older people with type 2 diabetes 

    E-Print Network [OSTI]

    Ding, Jie

    2010-11-24T23:59:59.000Z

    The deleterious effects of Type 2 diabetes on the brain have been shown to result in a greater prevalence of age-associated cognitive impairment and an enhanced risk of age-related cognitive decline in older diabetic ...

  17. Blood vessel detection in retinal images and its application in diabetic retinopathy screening 

    E-Print Network [OSTI]

    Zhang, Ming

    2009-05-15T23:59:59.000Z

    ....................................................................................... 122#1; B.#1; Instrument Control and Data Acquisition Tool .............................................. 124#1; C.#1; Daemon ........................................................................................................... 126#1; D.#1; Server.... .......................................................................................................... 22 6 Performance of direction prediction: (a) difference of two estimations, (b) prediction accuracy as function of a and two examples of prediction of 1+nq : (c) 0.5a ? and (d) 0.5a...

  18. Method for Confidence Metric in Optic Disk Location in Retinal Images -

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville PowerCherries 82981-1cnHighand Retrievals from aRodMIT-HarvardEnergy Innovation Portal Method

  19. TU Dortmund Fakultt Raumplanung, Dekanat | August-Schmidt-Str. 10 | 44227 Dortmund

    E-Print Network [OSTI]

    Kierfeld, Jan

    -europe.rp@tu-dortmund.de Fachschaft E: fs.rp@tu-dortmund.de W: www.fsrp.de Alumni-Gesellschaft Raumplanung E: alumni

  20. Acquiring a first language in adolescence : : Behavioral and neuroimaging studies in American Sign Language

    E-Print Network [OSTI]

    Ferjan Ramirez, Naja

    2013-01-01T23:59:59.000Z

    Dhond RP, Christenson N, Van Petten C, Marinkovic K, LewineDhond RP, Christenson N, Van Petten C, Marinkovic K, Lewine

  1. Abrupt learning and retinal size specificity in illusory-contour Nava Rubin*, Ken Nakayama* and Robert Shapley

    E-Print Network [OSTI]

    Rubin, Nava

    mechanisms subserving the two types of learning are commonly thought of as distinct. Here, we examine]. Besides the different timescales of the two types of learning, another character- istic differentiates. Consequently, the two types of learning are commonly thought to involve different underlying brain mechanisms

  2. Performance of photovoltaic arrays in-vivo and characteristics of prosthetic vision in animals with retinal degeneration

    E-Print Network [OSTI]

    Palanker, Daniel

    Performance of photovoltaic arrays in-vivo and characteristics of prosthetic vision in animals neurons. Subretinal photovoltaic arrays convert pulsed illumination into pulsed electric current produced by each pixel, and thereby assessing the changes in the implant performance over time. Ó 2014

  3. Transplantation of Adult Mouse iPS Cell-Derived Photoreceptor Precursors Restores Retinal Structure and Function in Degenerative Mice

    E-Print Network [OSTI]

    2011-01-01T23:59:59.000Z

    2007) Treatment of sickle cell anemia mouse model with iPSan animal model of sickle cell anemia [36], or engraftment

  4. Transcription factors SOX4 and SOX11 function redundantly to regulate the development of mouse retinal ganglion cells

    E-Print Network [OSTI]

    , Hangzhou Normal University, Hangzhou, Zhejiang 310036, China *Running title: Sox4 and Sox11 in RGC11 in retina results in a complete loss of RGCs. Conclusion: Sox4 and Sox11 function redundantly loss of RGCs was observed in Sox4/Sox11-null retinas, suggesting the two genes play similar roles

  5. A Novel PSK Demodulation Scheme Using 1bit-sampling Phase Comparison

    E-Print Network [OSTI]

    Choi, Woo-Young

    -II: Retinal Prosthesis ..............................................8 C. Conventional IQ-Demodulation Scheme IV. Implementation-II: Retinal Prosthesis ...........................................63 A. Circuit prosthesis...............................................................10 Figure 1.4 IQ

  6. Journal of Environmental Protection, 2012, 3, 1117-1123 doi:10.4236/jep.2012.329130 Published Online September 2012 (http://www.SciRP.org/journal/jep)

    E-Print Network [OSTI]

    Lin, C.-Y. Cynthia

    in Lin (2010), in which I use spatial econometrics to analyze air pollution externalities. In Lin (2010,6]. A secondary pollutant, ozone is not emitted directly but is formed in ambient air by chemical reactions in Econometrics to Measure Ozone Pollution Externalities C.-Y. Cynthia Lin Agricultural and Resource Economics

  7. Risk-Based Remediation Approach for Cs-137 Contaminated Sediment/Soils at the Savannah River Site (SRS) Lower Three Runs Tail (U) - 13348 - SRNS-RP-2012-00546

    SciTech Connect (OSTI)

    Freeman, Candice [Department of Energy- Savannah River Site, Aiken, SC (United States)] [Department of Energy- Savannah River Site, Aiken, SC (United States); Bergren, Christopher; Blas, Susan; Kupar, James [Area Completion Projects, Savannah River Nuclear Solutions, LLC (United States)] [Area Completion Projects, Savannah River Nuclear Solutions, LLC (United States)

    2013-07-01T23:59:59.000Z

    Lower Three Runs is a large blackwater stream that runs through the eastern and southern portion of the Savannah River Site. The Lower Three Runs watershed includes two SRS facility areas: P Area (P Reactor) and R Area (R Reactor) that provided effluent discharges to Lower Three Runs. During reactor operations, effluent discharges were well above natural (pre-industrial) or present day stream discharges. The watershed contains a 2,500-acre mainstream impoundment (PAR Pond), several smaller pre-cooler ponds, and a canal system that connects the pre-cooler ponds and discharges surface water to PAR Pond. From the PAR Pond dam, Lower Three Runs flows approximately 36 kilometers braiding through bottom-land/flood-plain forests before it enters the Savannah River. About eight kilometers downstream from the PAR Pond dam, the SRS boundary narrows (termed the Lower Three Runs tail) providing a limited buffer of DOE property for the Lower Three Runs stream and associated flood-plain. Previous screening characterization efforts revealed Cs-137 contamination in the sediment/soils of the flood-plain. As a part of the American Recovery and Reinvestment Act stimulus package, a comprehensive characterization effort was executed on the sediment/soils of the Lower Three Runs tail flood-plain providing a comprehensive look at the contaminant signature of the area. As a follow-up to that characterization, a regulatory decision Core Team, comprised of members of the South Carolina Department of Health and Environmental Control, Environmental Protection Agency - Region IV, and DOE, conducted negotiations on a risk-based approach to address the level of contamination found in the tail flood-plain as an early action that provided a long-term solution to exposure scenarios. For evaluation purposes, the adolescent trespasser was selected as the most likely human receptor for the Lower Three Runs tail portion because of the natural attractiveness of the area for recreational activities (i.e., hunting, fishing, hiking etc.) and access from public property. Exposure of the adolescent trespasser to Cs-137 contaminated sediment/soil at concentrations greater than 23.7 pico curies per gram have been calculated to result in an unacceptable cancer risk (> 1 x 10{sup -4}). Comparing the characterization sampling results conducted in 2009 with the benchmark concentration of 23.7 pCi/g, identified elevated risk levels along three sampling areas in the Lower Three Runs tail portion. On January 5, 2012, it was agreed by the core team that a Removal Action in the Lower Three Runs tail was to be conducted for the identified soil/sediment locations in the three identified areas that exceed the 1 x 10{sup -4} risk (23.7 pCi/g) for the adolescent trespasser receptor. The addition of Land Use Controls following the Removal Action was appropriate to protect human health and the environment. A systematic screening matrix was initiated at the identified hot spots (i.e., sampling points with Cs-137 activities greater than 23.7 pCi/g) to identify the limits of the excavation area. Sediment/soil within the defined removal areas would be excavated to the depth necessary to achieve the cleanup goal and disposed of in a CERCLA Off-Site Rule approved disposal facility. It was agreed that this removal action would adequately reduce the volume of available Cs-137 in the Lower Three Runs tail and consequently residual activities of the Cs-137 would decay over time reducing the amount of Cs-137 available in the tail which would curtail risk. The Land Use Controls consist of installation of an additional seven miles of fencing at major road crossings, utility easements, and at areas that showed a higher probability of access. In addition, signs were placed along the entire SRS perimeter of the Lower Three Runs tail approximately every 200 feet. Sign posts included both a No Trespassing sign and a Contaminant Warning sign. The project initiated a subcontract for both the removal action and the installation of fencing and signs on May 1, 2012. All field activities were completed

  8. American Journal of Analytical Chemistry, 2012, 3, 168-174 doi:10.4236/ajac.2012.32024 Published Online February 2012 (http://www.SciRP.org/journal/ajac)

    E-Print Network [OSTI]

    Hu, Qinhong "Max"

    December 15, 2011; revised January 20, 2012; accepted January 29, 2012 ABSTRACT Laser ablation coupled-Sum Method 1. Introduction Laser ablation coupled with inductively coupled plasma- mass spectrometry (LA, spatially heterogeneous distribution of elements in the intact rock at the scale of the laser spot

  9. Advances in Bioscience and Biotechnology, 2012, 3, 204-218 ABB doi:10.4236/abb.2012.33029 Published Online June 2012 (http://www.SciRP.org/journal/abb/)

    E-Print Network [OSTI]

    Hammock, Bruce D.

    Advances in Bioscience and Biotechnology, 2012, 3, 204-218 ABB doi:10.4236/abb.2012.33029 Published of Pharmacology, New York Medical College, Valhalla, New York, USA 2 Department of Medicine, Vanderbilt University of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, USA 5 Entomology and Cancer

  10. Open Journal of Molecular and Integrative Physiology, 2012, 2, 75-86 OJMIP doi:10.4236/ojmip.2012.23011 Published Online August 2012 (http://www.SciRP.org/journal/ojmip/)

    E-Print Network [OSTI]

    Cooper, Robin L.

    environmental temperature changes will impact sur- vival and in time the distribution of a species. The sig temperature on survival, heart rate and neural function in crayfish (Procambarus clarkii) and prawn (Macrobrachium rosenbergii) species Yoo Sun Chung, Richard M. Cooper, Justin Graff, Robin L. Cooper* Department

  11. Open Journal of Fluid Dynamics, 2012, 2, 35-43 doi:10.4236/ojfd.2012.22004 Published Online June 2012 (http://www.SciRP.org/journal/ojfd)

    E-Print Network [OSTI]

    Apte, Sourabh V.

    Open Journal of Fluid Dynamics, 2012, 2, 35-43 doi:10.4236/ojfd.2012.22004 Published Online June; accepted May 25, 2012 ABSTRACT In many applications, a moving fluid carries a suspension of droplets of a second phase which may change in size due to evaporation or condensation. Examples include liquid fuel

  12. 3-D INTEGRATION USING WAFER BONDING J.-Q. L *, A. KUMAR *, Y. KWON *, E.T. EISENBRAUN **, R.P. KRAFT *, J.F. McDONALD *, R.J.

    E-Print Network [OSTI]

    Salama, Khaled

    . McDonald et al. studied via holes formed by laser drilling, etching, Cu sputtering, and Au plating

  13. Materials Sciences and Applications, 2011, 2, 1427-1431 doi:10.4236/msa.2011.210193 Published Online October 2011 (http://www.SciRP.org/journal/msa)

    E-Print Network [OSTI]

    Cao, Guozhong

    Deposition of Titanium Oxide Nanoparticle Films for Dye-Sensitized Solar Cell Applications Jason Bandy the efficiency of the dye-sensitized solar cells with films created using electrophoretic deposition, the problem particles, efficiency of 4.91% with fill factor of 0.55 was obtained. Keywords: Dye-Sensitized Solar Cells

  14. Level MSc 2013/14 Medical Radiation Physics

    E-Print Network [OSTI]

    Martin, Ralph R.

    and Clinical Engineering 10 Credits Dr. RP Hugtenburg EGRM09 Radiation Protection 10 Credits Dr. RP HugtenburgLevel MSc 2013/14 Medical Radiation Physics MSc Medical Radiation Physics Coordinator: Dr. RP/Mr. SC Evans EGRM03 Radiation Physics 10 Credits Dr. RP Hugtenburg EGRM10 Radiotherapy Physics 10 Credits

  15. Predator satiation Periodical Cicadas in Ohio

    E-Print Network [OSTI]

    Mitchell, Randall J.

    ­ = Transmission coefficient (affected by ( y contagiousness and host behavior) · Rp = LS This is a molecular

  16. Shifts in the retinal image of a visual scene during saccades contribute to the perception of reached gaze direction in humans

    E-Print Network [OSTI]

    composed of light-emitting diodes, subjects first performed a rightward saccade of a great amplitude before

  17. Detecting pairwise correlations in spike trains: an objective comparison of methods and application to the study of retinal waves. Mathematical Details

    E-Print Network [OSTI]

    Cutts, CS; Eglen, SJ

    2014-08-13T23:59:59.000Z

    -spike-intervals (ISIs) sum to less than ?t and sum the contributions from all n. We also have to be careful not to double-count events: if we consider all the spike pairs formed when n inter-spike-intervals sum to less than ?t then most of those spike pairs will have... (?t) =probability that n successive ISIs sum to ? ?t, Pn =probability that outer two spikes are not both A or both B (can be synchronous), Sn =number of n successive ISIs in the recording. 3 and C = ?? n=1 Cn We find each quantity in turn: In(?t): Let the ith ISI...

  18. Adaptive optics microperimetry and OCT images show preserved function and recovery of cone visibility in macular telangiectasia type 2 retinal lesions

    E-Print Network [OSTI]

    2015-01-01T23:59:59.000Z

    imaging through adaptive optics. J Opt Soc Am A Opt Imageusing a confocal adaptive optics scanning ophthalmoscope.T, Campbell M. Adaptive optics scanning laser ophthalmosco-

  19. Multiple Species Reactive Chemical Transport in Groundwater: A Verification Exercise

    E-Print Network [OSTI]

    Narasimhan, T.N.

    2010-01-01T23:59:59.000Z

    Institute, under Contract EPRI RP2485-19, through U.S.tract RP2485-19. References EPRI, FASTCHEM A. package, andPower Research Institute (EPRI) has sponso_-ed the develop-

  20. Neural correlates of auditory word processing in infants and adults

    E-Print Network [OSTI]

    Travis, Katherine Elizabeth

    2011-01-01T23:59:59.000Z

    Dhond RP, Christensen N, Van Petten C, Marinkovic K, LewineOld-Infants. Cereb Cortex. Van Petten C, Coulson S, Rubin S,Dhond RP, Christensen N, Van Petten C, Marinkovic K, Lewine

  1. IAIFORIUA'IW3NPWCE!SSiNG LET MRS l(l971) 6%68.NORTH-HOLLAND PUBLISHING CY)@ANY Ret&ted 30 April 19' i

    E-Print Network [OSTI]

    Borodin, Allan

    (rP~). Thereffxe, an nth . c . polynomsal can be evaluated at fi porn;;; 141) operations,andatn pointsin

  2. Effects of Ocean Acidification on Learning in Coral Reef Maud C. O. Ferrari1

    E-Print Network [OSTI]

    Wisenden, Brian D.

    : Ferrari MCO, Manassa RP, Dixson DL, Munday PL, McCormick MI, et al. (2012) Effects of Ocean Acidification

  3. ECE 3040 Microelectronic Circuits Quiz 10 July 21, 2004

    E-Print Network [OSTI]

    Leach Jr.,W. Marshall

    . The potentiometer has a resistance RP = 100 k. The resistance from the potentiometer wiper to ground is labeled x

  4. Communications to the Editor Evidence of a Novel Side Chain Structure in

    E-Print Network [OSTI]

    McCullough, Richard D.

    -dodecylthiophene) (R-P3DDT), with 98% head- to-tail (HT) coupling of the alkyl side chains along the backbone, has" counterpart (IR-P3DDT) having only 75% HT linkages. R-P3DDT, which contains a high proportion of insulating samples studied, R-P3DDT and R-P3OT, i.e. poly(3-octylthiophene). This lamellar phase is found

  5. Annual Report: 0080412 Page 1 of 16

    E-Print Network [OSTI]

    , R.P. Gibbens, and M. Remmenga, "Persistence of biosolids in a Chihuahuan Desert rangeland 18 years

  6. 105 FERC 61,201 UNITED STATES OF AMERICA

    E-Print Network [OSTI]

    Laughlin, Robert B.

    transportation capacity to drive up natural gas prices in the periods immediately before and during Docket Nos. RP00-241-000 of the State of California RP00-241-006 RP00-241-008 v. El Paso Natural Gas of El Paso Natural Gas Company (El Paso Pipeline) and jointly, El Paso Merchant Energy-Gas, L.P. and El

  7. Rod and cone visual cycle consequences of a null mutation in the 11-cis-retinol dehydrogenase gene in man

    E-Print Network [OSTI]

    Palczewski, Krzysztof

    isomerization to all-trans-retinal (Pal- czewski & Saari, 1997). Critical to vision is the removal that retinal cells other than photoreceptors participate in this process (Bunt-Milam & Saari, 1983; Das et al

  8. Effect of shape and coating of a subretinal prosthesis on its integration with the retina

    E-Print Network [OSTI]

    Marc, Robert E.

    Effect of shape and coating of a subretinal prosthesis on its integration with the retina A form 13 September 2008 Available online 10 October 2008 Keywords: retinal prosthesis retinal migration

  9. The Roles of Transmembrane Domain Helix-III during Rhodopsin Photoactivation

    E-Print Network [OSTI]

    Ou, Wen-bin

    Background: Rhodopsin, the prototypic member of G protein-coupled receptors (GPCRs), undergoes isomerization of 11- cis-retinal to all-trans-retinal upon photoactivation. Although the basic mechanism by which rhodopsin is ...

  10. Spectral oximetry assessed with high-speed ultra-high-resolution optical coherence tomography

    E-Print Network [OSTI]

    Kagemann, Larry

    We use Fourier domain optical coherence tomography (OCT) data to assess retinal blood oxygen saturation. Three-dimensional disk-centered retinal tissue volumes were assessed in 17 normal healthy subjects. After removing ...

  11. Modulation of respiratory pumping behavior in the marine opisthobranch Aplysia californica

    E-Print Network [OSTI]

    Banneel, Natalie

    1993-01-01T23:59:59.000Z

    (B) in either the distribution of RP-interval frequencies or in each animal's control vs. experimental RP-interval frequency for each 30-sec increment of inter-RP-response intervals. . 20 Axes described in Figure 3. statistical analysis showed... that there was a significant difference, before ablation of the genital nerve (A) vs. after nerve ablation (B), in both the distribution of RP- interval frequencies for the 8 animals combined and in each animal's control vs. experimental RP-interval for 31...

  12. 1-4244-0842-3/07/$20.002007 IEEE TRANSDUCERS&EUROSENSORS'07

    E-Print Network [OSTI]

    Meng, Ellis

    -density arrays. Keywords: BioMEMS, Neural prosthesis, Parylene C, Retinal prosthesis. 1. INTRODUCTION Prototype-generation retinal prosthesis (Fig. 1), however, requires a high-density flexible Fig. 1 Placement and components of next- generation retinal prosthesis. electrode array and a high-lead-count cable to allow for high

  13. DEVELOPMENT OF A NATURAL GAS SYSTEMS ANALYSIS MODEL (GSAM) VOLUME I - SUMMARY REPORT VOLUME II - USER'S GUIDE VOLUME IIIA - RP PROGRAMMER'S GUIDE VOLUME IIIB - SRPM PROGRAMMER'S GUIDE VOLUME IIIC - E&P PROGRAMMER'S GUIDE VOLUME IIID - D&I PROGRAMMER'S GUIDE

    SciTech Connect (OSTI)

    Unknown

    2001-02-01T23:59:59.000Z

    This report summarizes work completed on DOE Contract DE-AC21-92MC28138, Development of a Natural Gas Systems Analysis Model (GSAM). The products developed under this project directly support the National Energy Technology Laboratory (NETL) in carrying out its natural gas R&D mission. The objective of this research effort has been to create a comprehensive, non-proprietary, microcomputer model of the North American natural gas market. GSAM has been developed to explicitly evaluate components of the natural gas system, including the entire in-place gas resource base, exploration and development technologies, extraction technology and performance parameters, transportation and storage factors, and end-use demand issues. The system has been fully tested and calibrated and has been used for multiple natural gas metrics analyses at NETL in which metric associated with NETL natural gas upstream R&D technologies and strategies under the direction of NETL has been evaluated. NETL's Natural Gas Strategic Plan requires that R&D activities be evaluated for their ability to provide adequate supplies of reasonably priced natural gas. GSAM provides the capability to assess potential and on-going R&D projects using a full fuel cycle, cost-benefit approach. This method yields realistic, market-based assessments of benefits and costs of alternative or related technology advances. GSAM is capable of estimating both technical and commercial successes, quantifying the potential benefits to the market, as well as to other related research. GSAM, therefore, represents an integration of research activities and a method for planning and prioritizing efforts to maximize benefits and minimize costs. Without an analytical tool like GSAM, NETL natural gas upstream R&D activities cannot be appropriately ranked or focused on the most important aspects of natural gas extraction efforts or utilization considerations.

  14. Environment-induced anisotropy and the sensitivity of the radical pair mechanism in the avian compass

    E-Print Network [OSTI]

    Alejandro Carrillo; Marcio F. Cornelio; Marcos C. de Oliveira

    2013-04-10T23:59:59.000Z

    Earth's magnetic field is essential for orientation in birds migration. The most promising explanation for this orientation is the photo-stimulated radical pair (RP) mechanism, conjectured to occur in cryptochrome photoreceptors. The radicals must have an intrinsic anisotropy in order to define a reference frame for the compass. This anisotropy, when introduced through hyperfine interactions, imposes immobility of the RP, and implies that entanglement between the unpaired electrons of the RP is preserved over long coherence times. We show that this kind of anisotropy, and consequently the entanglement in the model, are not necessary for the proper functioning of the compass. Classically correlated initial conditions for the RP, subjected to a fast decoherence process, are able to provide the anisotropy required. The environment in which the RP is immersed is then responsible for the reference frame of the compass, relaxing the immobility assumption. This fact significantly expands the range of applicability of the RP mechanism providing more elements for experimental search.

  15. Dynamic analysis of a semi-submersible connected to a tanker

    E-Print Network [OSTI]

    Maldonado-Aguirre, Georgina

    1993-01-01T23:59:59.000Z

    frequency oscillation. 2. 16 Reproduction of API RP2P curve . 2. 17 Sedco 711 surge motion for low frequency motion calculations. 2. 18 Sedco 711 surge motion for low frequency motion calculations; details of 20 sec, surrounding extreme. . 2. 19 Curve... institutes (API) "Recommended Practices for The Analysis of Spread Mooring Systems for Floating Drilling Units (RP2P)" [18]. API RP2P contains an upper bound curve for the relationship between spectral significant wave height, mean wave drift force...

  16. Optical Filter Design: Gain Analysis and Tolerance Analysis

    E-Print Network [OSTI]

    Vandrasi, Vivek

    2011-10-21T23:59:59.000Z

    Psat : : : : : : : : : : : : : : 23 15 Magnitude, phase responses and group delay of a unit cell : : : : : : 25 16 Magnitude response across (top) broadband and (bottom) nar- rowband for baseline design: Rp = 12dB : : : : : : : : : : : : : : : : 25 ix FIGURE Page 17 Magnitude... response across (top) broadband and (bottom) nar- rowband for baseline design: Rp = 18dB : : : : : : : : : : : : : : : : 26 18 Magnitude response across (top) broadband and (bottom) nar- rowband for cascade design: Rp = 12d...

  17. Supplementary Figure S1. Light-associated motor responses of worms expressing (b)opsin in neurons. a, Vigorously crawling TG animals pre-incubated with 10 M 9-cis-retinal and expressing

    E-Print Network [OSTI]

    Palczewski, Krzysztof

    responses to light were recorded and scored. Data represent three independent experiments with 3- 10 worms s and their motor responses were scored. Data represent three independent experiments with 3-7 animals each. Error bars indicate S.E.M. c, Day 1 TG animals expressing (b)opsin in neurons were pretreated with 10 µM 9

  18. Towards functional regeneration of the central nervous system : glial calcium signaling in reactive gliosis and the therapeutic potential of bone marrow-derived mesenchymal stem cells for retinal degenerative diseases

    E-Print Network [OSTI]

    Yu, Diana Xuan

    2008-01-01T23:59:59.000Z

    Petri dishes (MatTek Corp. , Ashland MA) at ~200,000 cells/Petri dishes (MatTek Corp. , Ashland MA) at ~200,000 cells/bottom dishes (MakTek, Ashland, MA). Cells were allowed to

  19. anneli zirkel jaanus: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Option Introduction la tricolores l'intersection d'une route principale RP et d'une route secondaire RS. Le principe utilis est Pierre, Laurence 139 Universit...

  20. A cross-sectional study of the prevalence and risk factors for hypertension in rural Nepali women

    E-Print Network [OSTI]

    2013-01-01T23:59:59.000Z

    and risk factors for hypertension in rural Nepali women. BMCHe J: Global burden of hypertension: analysis of worldwideNeupane RP: Prevalence of hypertension in a rural community

  1. U.S. Department of Energy Categorical Exclusion ...

    Broader source: Energy.gov (indexed) [DOE]

    Site AikenAikenSouth Carolina Install groundwater monitoring wells using Rotosonic drilling according to F-Area Tank Farm Groundwater Monitoring Plan SRNS- RP-2011-00995....

  2. Investigation of the Effect of In-Situ Catalyst on the Steam Hydrogasification of Biomass

    E-Print Network [OSTI]

    FAN, XIN

    2012-01-01T23:59:59.000Z

    Overend, R.P. , Biomass and renewable fuels, Fuel Processingto use as the biomass feedstock for renewable electricity12, 13]. Biomass is the only renewable energy source to

  3. Room air stratification in combined chilled ceiling and displacement ventilation systems.

    E-Print Network [OSTI]

    Schiavon, Stefano; Bauman, Fred; Tully, Brad; Rimmer, Julian

    2012-01-01T23:59:59.000Z

    and displacement ventilation systems. HVAC&R Research, 12 (and displacement ventilation system. ASHRAE RP-1438 Finalof Displacement Ventilation System—Experimental and

  4. E-Print Network 3.0 - ampicillin resistant escherichia Sample...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    201-210. Griffiths, R.P., Moyer, C... and untransformed bacterial clones were grown in media with or without ... Source: Smith, M. Alex - Biodiversity Institute of Ontario &...

  5. Hemolymph factors affecting respiratory pumping in Aplysia californica

    E-Print Network [OSTI]

    Tigert, Susan Jill

    1991-01-01T23:59:59.000Z

    statistically compared using the Wilcoxon Rank Sum Test (Ott, 1987) in the following manner: an average RP burst rate/30 minutes prior to an injection was calculated for each animal and compared with the number of RP bursts in the 30 minutes following... patterned series of RP responses characterized by a regular increase in the inter-RP response intervals; seizure durations range from 30-90 minutes. RPS occur infrequently (0-3/animal/24 hours), but their occurrence is more likely after an extended...

  6. OCEAN THERMAL ENERGY CONVERSION PRELIMINARY DATA REPORT FOR THE NOVEMBER 1977 GOTEC-02 CRUISE TO THE GULF OF MEXICO MOBILE SITE

    E-Print Network [OSTI]

    Commins, M.L.

    2010-01-01T23:59:59.000Z

    Sci. Letts. , 1I, 38- Bruland, K.W. , R.P. Franks, G.A.gradients as the nutrients (Bruland et al~, 1979 and Boyle,

  7. TU Dortmund | Fakultt Raumplanung Dekanat Studien-und Projektzentrum (SPZ)

    E-Print Network [OSTI]

    Kierfeld, Jan

    Fachschaft Raumplanung E-Mail: fs.rp@tu-dortmund.de www.fsrp.de, Tel. (0231) 755-2383. Stand 06.08.2014 2 / 3

  8. An integrated top-down and bottom-up strategy for broadly characterizi...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    employs high resolution reversed phase (RP) LC separations coupled on-line with a 12T Fourier transform ion cyclotron resonance (FTICR) spectrometer to profile and tentatively...

  9. CONTINUOUS NORM AND ABSOLUTELY CONTINUOUS NORM IN BANACH FUNCTION SPACES ARE NOT THE SAME

    E-Print Network [OSTI]

    Lang, Jan

    presented by C. Bennet and R. Sha* *rp- ley in [1]. The first one [1, Corollary 4.4] shows that a Banach

  10. Proceedings of the Symposium: Current Perspectives on the Physical and Biological Processes of Humboldt Bay, March 2004

    E-Print Network [OSTI]

    Schlosser, S. C.

    2007-01-01T23:59:59.000Z

    pri- mary productivity (Bixler 1982). However, as is theProg Ser 223:133–141 Bixler RP (1982) Primary productivity

  11. astrocyte cell line: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    autonomy in an induced pluripotent stem cell model of TDP-43 Edinburgh, University of 6 Propagation of Intercellular Calcium Waves in Retinal Astrocytes and Mu ller Cells Biology...

  12. astrocytic cancer cells: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    autonomy in an induced pluripotent stem cell model of TDP-43 Edinburgh, University of 6 Propagation of Intercellular Calcium Waves in Retinal Astrocytes and Mu ller Cells Biology...

  13. Technische Universitat Bernstein Center for Berlin Computational Neuroscience

    E-Print Network [OSTI]

    Wiskott, Laurenz

    's Thesis Self-organization Of V1 Complex-Cells Based On Slow Feature Analysis And Retinal Waves Sven D¨ahne

  14. augments trail-mediated apoptosis: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    device for patients Biology and Medicine Websites Summary: : augmented reality, field expander, head mounted device, mobility performance, night blindness, retinitisEvaluation...

  15. Global polarization measurement in Au plus Au collisions

    E-Print Network [OSTI]

    Abelev, B. I.; Aggarwal, M. M.; Ahammed, Z.; Anderson, B. D.; Arkhipkin, D.; Averichev, G. S.; Bai, Y.; Balewski, J.; Barannikova, O.; Barnby, L. S.; Baudot, J.; Baumgart, S.; Belaga, V. V.; Bellingeri-Laurikainen, A.; Bellwied, R.; Benedosso, F.; Betts, R. R.; Bhardwaj, S.; Bhasin, A.; Bhati, A. K.; Bichsel, H.; Bielcik, J.; Bielcikova, J.; Bland, L. C.; Blyth, S. -L; Bombara, M.; Bonner, B. E.; Botje, M.; Bouchet, J.; Brandin, A. V.; Burton, T. P.; Bystersky, M.; Cai, X. Z.; Caines, H.; Sanchez, Calderon de la Barca; Callner, J.; Catu, O.; Cebra, D.; Cervantes, M. C.; Chajecki, Z.; Chaloupka, P.; Chattopadhyay, S.; Chen, H. F.; Chen, J. H.; Chen, J. Y.; Cheng, J.; Cherney, M.; Chikanian, A.; Christie, W.; Chung, S. U.; Clarke, R. F.; Codrington, M. J. M.; Coffin, J. P.; Cormier, T. M.; Cosentino, M. R.; Cramer, J. G.; Crawford, H. J.; Das, D.; Dash, S.; Daugherity, M.; de Moura, M. M.; Dedovich, T. G.; DePhillips, M.; Derevschikov, A. A.; Didenko, L.; Dietel, T.; Djawotho, P.; Dogra, S. M.; Dong, X.; Drachenberg, J. L.; Draper, J. E.; Du, F.; Dunin, V. B.; Dunlop, J. C.; Mazumdar, M. R. Dutta; Edwards, W. R.; Efimov, L. G.; Emelianov, V.; Engelage, J.; Eppley, G.; Erazmus, B.; Estienne, M.; Fachini, P.; Fatemi, R.; Fedorisin, J.; Feng, A.; Filip, P.; Finch, E.; Fine, V.; Fisyak, Y.; Fu, J.; Gagliardi, Carl A.; Gaillard, L.; Ganti, M. S.; Garcia-Solis, E.; Ghazikhanian, V.; Ghosh, P.; Gorbunov, Y. N.; Gos, H.; Grebenyuk, O.; Grosnick, D.; Grube, B.; Guertin, S. M.; Guimaraes, K. S. F. F.; Gupta, A.; Gupta, N.; Haag, B.; Hallman, T. J.; Hamed, A.; Harris, J. W.; He, W.; Heinz, M.; Henry, T. W.; Heppelmann, S.; Hippolyte, B.; Hirsch, A.; Hjort, E.; Hoffman, A. M.; Hoffmann, G. W.; Hofman, D. J.; Hollis, R. S.; Horner, M. J.; Huang, H. Z.; Hughes, E. W.; Humanic, T. J.; Igo, G.; Iordanova, A.; Jacobs, P.; Jacobs, W. W.; Jakl, P.; Jones, P. G.; Judd, E. G.; Kabana, S.; Kang, K.; Kapitan, J.; Kaplan, M.; Keane, D.; Kechechyan, A.; Kettler, D.; Khodyrev, V. Yu; Kiryluk, J.; Kisiel, A.; Kislov, E. M.; Klein, S. R.; Knospe, A. G.; Kocoloski, A.; Koetke, D. D.; Kollegger, T.; Kopytine, M.; Kotchenda, L.; Kouchpil, V.; Kowalik, K. L.; Kravtsov, P.; Kravtsov, V. I.; Krueger, K.; Kuhn, C.; Kulikov, A. I.; Kumar, A.; Kurnadi, P.; Kuznetsov, A. A.; Lamont, M. A. C.; Landgraf, J. M.; Lange, S.; LaPointe, S.; Laue, F.; Lauret, J.; Lebedev, A.; Lednicky, R.; Lee, C. -H; Lehocka, S.; LeVine, M. J.; Li, C.; Li, Q.; Li, Y.; Lin, G.; Lin, X.; Lindenbaum, S. J.; Lisa, M. A.; Liu, F.; Liu, H.; Liu, J.; Liu, L.; Ljubicic, T.; Llope, W. J.; Longacre, R. S.; Love, W. A.; Lu, Y.; Ludlam, T.; Lynn, D.; Ma, G. L.; Ma, J. G.; Ma, Y. G.; Mahapatra, D. P.; Majka, R.; Mangotra, L. K.; Manweiler, R.; Margetis, S.; Markert, C.; Martin, L.; Matis, H. S.; Matulenko, Yu A.; McShane, T. S.; Meschanin, A.; Millane, J.; Miller, M. L.; Minaev, N. G.; Mioduszewski, Saskia; Mischke, A.; Mitchell, J.; Mohanty, B.; Morozov, D. A.; Munhoz, M. G.; Nandi, B. K.; Nattrass, C.; Nayak, T. K.; Nelson, J. M.; Nepali, C.; Netrakanti, P. K.; Nogach, L. V.; Nurushev, S. B.; Odyniec, G.; Ogawa, A.; Okorokov, V.; Olson, D.; Pachr, M.; Pal, S. K.; Panebratsev, Y.; Pavlinov, A. I.; Pawlak, T.; Peitzmann, T.; Perevoztchikov, V.; Perkins, C.; Peryt, W.; Phatak, S. C.; Planinic, M.; Pluta, J.; Poljak, N.; Porile, N.; Poskanzer, A. M.; Potekhin, M.; Potrebenikova, E.; Potukuchi, B. V. K. S.; Prindle, D.; Pruneau, C.; Pruthi, N. K.; Putschke, J.; Qattan, I. A.; Raniwala, R.; Raniwala, S.; Ray, R. L.; Relyea, D.; Ridiger, A.; Ritter, H. G.; Roberts, J. B.; Rogachevskiy, O. V.; Romero, J. L.; Rose, A.; Roy, C.; Ruan, L.; Russcher, M. J.; Sahoo, R.; Sakrejda, I.; Sakuma, T.; Salur, S.; Sandweiss, J.; Sarsour, M.; Sazhin, P. S.; Schambach, J.; Scharenberg, R. P.; Schmitz, N.; Seger, J.; Selyuzhenkov, I.; Seyboth, P.; Shabetai, A.; Shahaliev, E.; Shao, M.; Sharma, M.; Shen, W. Q.; Shimanskiy, S. S.; Sichtermann, E. P.; Simon, F.; Singaraju, R. N.; Smirnov, N.; Snellings, R.; Sorensen, P.; Sowinski, J.; Speltz, J.; Spinka, H. M.; Srivastava, B.; Stadnik, A.; Stanislaus, T. D. S.; Staszak, D.; Stock, R.; Strikhanov, M.; Stringfellow, B.; de Toledo, A. Szanto; Takahashi, J.; Tang, A. H.; Tarnowsky, T.; Thomas, J. H.; Timmins, A. R.; Timoshenko, S.; Tokarev, M.; Trainor, T. A.; Trentalange, S.; Tribble, Robert E.; Tsai, O. D.; Ulery, J.; Ullrich, T.; Underwood, D. G.; Van Buren, G.; van der Kolk, N.; van Leeuwen, M.; Molen, A. M. Vander; Varma, R.; Vasilevski, I. M.; Vasiliev, A. N.; Vernet, R.; Vigdor, S. E.; Viyogi, Y. P.; Vokal, S.; Voloshin, S. A.; Wada, M.; Waggoner, W. T.; Wang, F.; Wang, G.; Wang, J. S.; Wang, X. L.; Wang, Y.; Webb, J. C.; Westfall, G. D.; Whitten, C., Jr.; Wieman, H.; Wissink, S. W.; Witt, R.; Wu, J.; Wu, Y.; Xu, N.; Xu, Q. H.

    2007-01-01T23:59:59.000Z

    angle by #8;RP ? #8;RP + pi . A. Technique The main components of the detector system used in this analysis are the STAR main time projection chamber (TPC) [11], two STAR forward TPCs [12], and the STAR zero degree calorimeter shower maximum...

  16. Copyright by International OCSCO World Press. All rights reserved. 2006 Research paper 101

    E-Print Network [OSTI]

    Fernandez, Thomas

    manufacturing parameters of RP technologies. Additionally, any user of the PolyJetTM RP machine can use-June 2006 Research paper 101 of Achievements in Materials and Manufacturing Engineering of Achievements in Materials and Manufacturing Engineering Optimizing scale factors of the PolyJetTM rapid prototyping

  17. Evaluation of the TEOM method for the measurement of particulate matter for Texas cattle feedlots

    E-Print Network [OSTI]

    Skloss, Stewart James

    2009-05-15T23:59:59.000Z

    and Patashnick (R&P) Series1400a monitors. The R&P Series 1400a monitor uses the TEOM method to measure particulate matter (PM) concentrations and was approved by EPA in 1990 as an automated equivalent method PM10 sampler. Since its approval, many state air...

  18. Design and analysis of a cathode phase inverter circuit

    E-Print Network [OSTI]

    Banerjee, Haridas

    1959-01-01T23:59:59.000Z

    Rl = Z01 70= pl= p2 44 000 ohms = rp 1 = p2 84, 000 ohms 28, 000 ohms (a = 3) 900 ohms (for balance), from equation 13b From equation 16, 28x10 44x10 + . 9x10 x71 44+84 x10 3 + 3 (. 9 x 71 + 44 + 84) x 10 3 . 9 x 10 x 71 (44 + 84) x 10 28 x...) Where D = 4ilR+ R+ rP1+ RI)(p2R+ R+ rP2+ R2) - (AIR+ R)(p2R+ R) 1+ pl (p2R+ R+ rp2+ R2) + (P1R+ P)(zp2+ R2 (R2 + rp2) &g' 1 + - + rp] + Rl) + g' 2R + R) (rpl + Rl) 01 = I Rl = lEs5, 2R + R + rp2 + R2) Rl Pl , . (9) -P1Esg2R + R) R2 E02 = Ip2R2 = (10...

  19. Real Time Grid Reliability Management 2005

    E-Print Network [OSTI]

    Eto, Joe

    2008-01-01T23:59:59.000Z

    CERTS CIEE DOE EIPP EMS EPG EPRI LBNL LMP LMTF MRTU NERC PDCVersion 2.1, User’s Manual, EPRI Research ProjectRP30400-01,Version 2.1, User’s Manual, EPRI Research ProjectRP30400-01,

  20. Ultrasound in Med. & Bidl. Vol. 8. pp. 207-208 Printed in Great Britain. All rights reserved

    E-Print Network [OSTI]

    Illinois at Urbana-Champaign, University of

    . Ultrasound Med. Biol. 7:267-273. Liburdy, R.P. (1979). Radiofrequency radiation alters the immune system. Res. 77~34-46. Liburdy, R.P. (1980). Radiofrequency radiation alters the immune system. II. Modulation exper- imental groups: one group received radiofrequency radiation (RFR) on a single occasion

  1. De Novo Initiated RNA Synthesis by the Hepatitis C Virus RNA-dependent RNA Polymerase

    E-Print Network [OSTI]

    Reddy Chinnaswamy, Sreedhar

    2011-08-08T23:59:59.000Z

    Nonstructural NTPs Nucleotide triphosphates viii PE Primer extension pRb Retinoblastoma protein RC Replication complex RdRp RNA-dependent RNA polymerase REM... 23 Effects of recombinant cyclophilin A and pRb on RNA synthesis by the HCV RdRp ????????????????????? 84 24 ?1 loop-like structures in other viral RdRps ????????? 86 25 A model for RNA...

  2. Fast decomposition of p-groups in the Roquette category, for p > 2

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Fast decomposition of p-groups in the Roquette category, for p > 2 Serge Bouc Abstract : Let p be a prime number. In [9], I introduced the Roquette category Rp of finite p-groups, which is an additive tensor category containing all finite p-groups among its objects. In Rp, every finite p-group P admits

  3. Extreme Events Met Data and Modeling

    E-Print Network [OSTI]

    Firestone, Jeremy

    IEC 61400-3 Consensus leaning towards ­ IEC 61400-3, Section 12 for Hurricanes ­ 50 year RP event, w min winds @10m ASL ­ Given for any RP /Saffir Scale, by region Translate NHC data into IEC Wind Class;NHC - Return Periods NHC Data Tuesday, July 2, 2013 #12;Averaging Time Conversion ­ IEC ­ multiply 10

  4. AN IMPROVED TREATMENT OF RESIDUAL STRESSES IN FLAW ASSESSMENT OF PIPES AND PRESSURE VESSELS FABRICATED FROM FERRITIC STEELS

    E-Print Network [OSTI]

    Michaleris, Panagiotis

    draft of API RP-579, Recommended Practice for Fitness-for-Service. INTRODUCTION When performing standards. While welding residual stresses can reach or exceed yield in certain situations. These recommendations have been proposed for inclusion in the current draft of API RP-579, Recommended Practice

  5. Development/Plasticity/Repair The Bone Morphogenetic Protein Roof Plate Chemorepellent

    E-Print Network [OSTI]

    Butler, Samantha

    Development/Plasticity/Repair The Bone Morphogenetic Protein Roof Plate Chemorepellent Regulates, Toronto, Ontario, Canada M5G 1X8 Commissural spinal axons extend away from the roof plate (RP) in response to the dorsal midline and are generated by the bone morphogenetic proteins (BMPs) in the roof plate (RP) (Liem

  6. ExtraSolar Planets Finding Extrasolar Planets. I

    E-Print Network [OSTI]

    Walter, Frederick M.

    Planets. IV Most planets have been found by Doppler Wobble (radial velocity variations). This selects/m* rp (center of mass) V* = 2 mp/m* / (rp)1/2 V¤ = 2 cm/s; V¤J = 3 m/s #12;Doppler Effect Emission from The Doppler Effect applied to pulse arrival times. Applicable to pulsar planets #12;Finding Extrasolar Planets

  7. 308 2005 ASHRAE. The recent ASHRAE project, "Updating the ASHRAE/

    E-Print Network [OSTI]

    Heating and Cooling Load Calculation Procedures and Data" (1199-RP), developed two new resi- dential load, "Updating the ASHRAE/ACCA Residential Heating and Cooling Load Calculation Proce- dures and Data" (1199-RP and data are presented in the "Residential Cooling and Heating Loads Calculation" chapter of the 2005

  8. 2005 ASHRAE. 291 The recent ASHRAE project, "Updating the ASHRAE/

    E-Print Network [OSTI]

    Heating and Cooling Load Calculation Procedures and Data" (RP-1199), developed two new resi- dential loads in the developmentofothermethods.ResultscomparingRLFtoRHB are presented. The RLF heating load calculation is also described/ACCA Residential Heating and Cooling Load Calculation Proce- dures and Data" (RP-1199), had two primary products

  9. Binary recycled pulsars, as a most precise physical laboratory

    E-Print Network [OSTI]

    G. S. Bisnovatyi-Kogan

    2008-02-08T23:59:59.000Z

    The following problems are discussed. 1. Pulsars and close binaries. 2. Hulse-Taylor pulsar. 3. Disrupted pulsar pairs. 4. RP statistics. 5. Enhanced evaporation: formation of single RP. 6. General relativity effects: NS+NS. 7. A Double pulsar system. 8. Checking general relativity. 9. Variability of the gravitational constant. 10. Space Watch.

  10. Phase separation of acetonitrile-water mixture in protein purification

    E-Print Network [OSTI]

    Gu, Tingyue

    Phase separation of acetonitrile-water mixture in protein purification Tingyue Gu, Yesong Gu The removal of acetonitrile (ACN)from reversed-phase high performance liquid chromatography (RP- HPLC the majority of ACN after RP-HPLC. Keywords. purification; chromatography; acetonitrile; protein; human growth

  11. Design and Performance Analysis of an Aeronautical Routing Protocol with Ground Station Updates

    E-Print Network [OSTI]

    Narra, Hemanth

    2011-08-31T23:59:59.000Z

    Aeronautical routing protocol (AeroRP) is a position-based routing protocol developed for highly dynamic airborne networks. It works in conjunction with the aeronautical network protocol (AeroNP). AeroRP is a multi-modal protocol that operates...

  12. Erk phosphorylates threonine 42 residue of ribosomal protein S3

    SciTech Connect (OSTI)

    Kim, Hag Dong [Laboratory of Biochemistry, School of Life Sciences and Biotechnology, and BioInstitute, Korea University, Seoul 136-701 (Korea, Republic of); Lee, Jae Yung [Department of Biology, Mokpo National University, Chonnam 534-729 (Korea, Republic of); Kim, Joon [Laboratory of Biochemistry, School of Life Sciences and Biotechnology, and BioInstitute, Korea University, Seoul 136-701 (Korea, Republic of)]. E-mail: joonkim@korea.ac.kr

    2005-07-22T23:59:59.000Z

    The ribosomal protein S3 (rpS3) is involved in ribosome biogenesis as a member of ribosomal small subunit and also plays a role in the repair of damaged DNA. Extracellular signal-regulated kinase (Erk), a MAP kinase, is known to play important roles in the regulation of cell growth, differentiation, and apoptosis. In this study, the sequence analysis of rpS3 protein revealed that this protein has a putative FXFP motif which is believed to be an Erk binding site. Indeed, the motif was demonstrated as an Erk binding site by co-immunoprecipitation. In addition to this, it was revealed that Erk specifically phosphorylated Thr 42 residue of rpS3 in vitro and in vivo using the various mutants of rpS3. Taken together, rpS3 appears to be phosphorylated by activated Erk in proliferating cells, resulting in the decreased interaction between two proteins.

  13. American Journal of Hypertension 1 Original article

    E-Print Network [OSTI]

    Zabulis, Xenophon

    American Journal of Hypertension 1 Original article Divergent Retinal Vascular Abnormalities in Normotensive Persons and Patients With Never-Treated, Masked, White Coat Hypertension Areti Triantafyllou,1 Haidich,4 Chrysanthos Zamboulis1 and Stella Douma1 Background Hypertensive patients with retinal

  14. HDR CFA IMAGE RENDERING David Alleysson,1

    E-Print Network [OSTI]

    Alleysson, David

    HDR CFA IMAGE RENDERING David Alleysson,1 Laurence Meylan,2 and Sabine S¨usstrunk2 1Laboratory of the already demosaiced image. This render- ing is closer to retinal processing where an image is acquired framework, demosaicing is the final step of the rendering. Our method, inspired by retinal sampling

  15. First-order design of off-axis reflective ophthalmic adaptive optics systems using afocal

    E-Print Network [OSTI]

    First-order design of off-axis reflective ophthalmic adaptive optics systems using afocal for designing laser cavities, spectrographs and adaptive optics retinal imaging systems. The use, range respectively. This is discussed using examples from adaptive optics retinal imaging systems. The performance

  16. Received 20 Oct 2012 | Accepted 29 Apr 2013 | Published 18 Jun 2013 Cortical responses elicited by photovoltaic

    E-Print Network [OSTI]

    Palanker, Daniel

    elicited by photovoltaic subretinal prostheses exhibit similarities to visually evoked potentials Yossi developed a wireless photovoltaic retinal prosthesis, in which camera- captured images are projected onto, yet the inner retinal neurons (inner nuclear and ganglion cell layers) that process the visual signals

  17. Method and system for assigning a confidence metric for automated determination of optic disc location

    DOE Patents [OSTI]

    Karnowski, Thomas P. (Knoxville, TN); Tobin, Jr., Kenneth W. (Harriman, TN); Muthusamy Govindasamy, Vijaya Priya (Knoxville, TN); Chaum, Edward (Memphis, TN)

    2012-07-10T23:59:59.000Z

    A method for assigning a confidence metric for automated determination of optic disc location that includes analyzing a retinal image and determining at least two sets of coordinates locating an optic disc in the retinal image. The sets of coordinates can be determined using first and second image analysis techniques that are different from one another. An accuracy parameter can be calculated and compared to a primary risk cut-off value. A high confidence level can be assigned to the retinal image if the accuracy parameter is less than the primary risk cut-off value and a low confidence level can be assigned to the retinal image if the accuracy parameter is greater than the primary risk cut-off value. The primary risk cut-off value being selected to represent an acceptable risk of misdiagnosis of a disease having retinal manifestations by the automated technique.

  18. active episomal hat: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Both the planet and host star are smaller than previously believed; our analysis yields Rp4.31 +-0.06 Earth-radii, and Rs 0.683 +-0.009 solar radii, both about 3-sigma...

  19. RELIABILITY OF WIND POWER FROM DISPERSED SITES: A PRELIMINARY ASSESSMENT

    E-Print Network [OSTI]

    Kahn, E.

    2011-01-01T23:59:59.000Z

    in El ectric Utility Systems, EPRI RP 651-1, Summary Report,380 MW. ELCC of 430 MW. EPRI, however, estimates At thatthey were as bad as the EPRI estimate, both of the proposed

  20. A 2 MEG-AMPERE PROTOTYPE LEVITATED COIL FOR MULTIPOLE FUSION

    E-Print Network [OSTI]

    Green, M.A.

    2010-01-01T23:59:59.000Z

    Power Research Institute (EPRI) agreement RP1190-1 with TRW.Power Research Institute (EPRI), May 1977. 9. M. A. Green, "by TRW ' and funded by EPRI. Many of the concepts developed

  1. This paper has been downloaded from the Building and Environmental Thermal Systems Research Group at Oklahoma State University

    E-Print Network [OSTI]

    Project RP-1356. ABSTRACT Mechanical pipe insulation systems are installed around cold cylindrical conductivity is needed for the design of insulation systems in chiller pipe applications. In this paper specimen average temperature and wall thicknesses. Corresponding uncertainties of the measurements

  2. Calculation of the Solar Load onto Occupants in a Room using Bidirectional Scattering Distribution Functions and a View Factor Approach

    E-Print Network [OSTI]

    Jedek, Christoph

    2012-01-01T23:59:59.000Z

    J.A. , Beckman, W.A. (1991). Solar engineering of thermalA new method for predicting the solar heat gain of complexfenestration systems. ASHRAE Solar Heat Gain Project 548-RP

  3. Notation Index (there exists) Fn-4

    E-Print Network [OSTI]

    Bernstein, Daniel

    -subsets of A) CL-15, Fn-1 |A| (cardinality) CL-3, CL-14 X (standard deviation) Fn-25 S(n, k) (Stirling numbers is equivalent GT-27 probabilistic DT-30 RP-tree is equivalent GT-27 Towers of

  4. E-Print Network 3.0 - affects aromatase inhibitor Sample Search...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Neuroendocrinology 2003;78:3644 Summary: AN, Zumpe D, Michael RP: Intracere- bral infusion of an aromatase inhibitor, sexual behavior... ;81:2171-2178. 46 Marsh DA, Brodie HJ,...

  5. DIVIDE AND CONQUER ROADMAP FOR ALGEBRAIC SETS ...

    E-Print Network [OSTI]

    2014-06-24T23:59:59.000Z

    Jun 18, 2014 ... SAUGATA BASU AND MARIE-FRANÇOISE ROY .... pk,. (2) a finite subset of points of N ? Rp. The set V 0 and the finite set N are not arbitrary ...

  6. Battery Pack Requirements and Targets Validation

    Broader source: Energy.gov (indexed) [DOE]

    in the U.S. Light-Duty Vehicle Fleet. MIT LFEE-2007 03 RP. 14 According to the Only MIT Simulation Test, a 35% Reduction in PHEV Power Causes a Drop of Fuel Saved of Only 10%...

  7. Oral melanoma: An unusual presentation

    E-Print Network [OSTI]

    Lessa, Nara Lidia; Moleri, Andrea Braga; Merly, Flavio; Moreira, Luiz Carlos; Moreira, Mirian Jordao; Antunes, Heliton Spindola

    2008-01-01T23:59:59.000Z

    CM. Oral mucosal melanoma: epidemiology and pathobiology.PubMed 2. Rapini RP. Oral melanoma: Diagnosis and treatment.JM, Soriano JAM, Perez ML. Melanoma de paladar duro. Acta

  8. E-Print Network 3.0 - astrophysical rapid proton-capture Sample...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Neutron and proton capture reactions... explosions 3, as well ass type I X-ray bursts (rapid proton capture process, rp-process) 4, and might... iron 2. Meanwhile...

  9. Neuron, Vol. 24, 127141, September, 1999, Copyright 1999 by Cell Press BMPs as Mediators of Roof Plate Repulsion

    E-Print Network [OSTI]

    Butler, Samantha

    Neuron, Vol. 24, 127­141, September, 1999, Copyright ©1999 by Cell Press BMPs as Mediators of Roof., 1997). that the roof plate (RP) expresses a diffusible activity One source of FP-independent guidance

  10. Galen Sasaki University of Hawaii 1 Detectors

    E-Print Network [OSTI]

    Sasaki, Galen H.

    is inversely proportional to thermal noise Rp is inversely proportional to bandwidth RL RL/(A+1) But thermal · Extinction ratio: output power-ON/output power-OFF · Insertion loss · Crosstalk · Polarization dependent loss

  11. arXiv:astroph/0007038 A&A manuscript no.

    E-Print Network [OSTI]

    Saglia, Roberto P.

    , and fit logarithmic gradients in the range \\Gamma0:2 to 0.1 mag per decade. These values are similar of the monolithic collapse `a la Larson (1974) Send offprint requests to: R.P. Saglia (email: saglia

  12. ELLIPSOMETRY AFPO Group Laboratoire de physique des solides -CNRS & Universite Paris Sud-11

    E-Print Network [OSTI]

    Paris-Sud 11, Université de

    : = rp rs = tan()ei Consequences: · ellipsometry is very robust, accurate, and reproducible 1.41 0 PS 1.58 0 3 Brewster microscopy This microscopy technique allows the direct observation

  13. A "joint+marginal" approach to parametric polynomial optimization

    E-Print Network [OSTI]

    Jean B. Lasserre

    2010-01-13T23:59:59.000Z

    Jan 13, 2010 ... Abstract: Given a compact parameter set $Y\\subset R^p$, we ... all information about all global optimal solutions $x^*(y)$ of $P_y$, as $y\\in Y$.

  14. Current Perspectives on the Physical and Biological Processes of Humboldt Bay

    E-Print Network [OSTI]

    Schlosser, S. C.; Rasmussen, R.

    2007-01-01T23:59:59.000Z

    Canada. Toronto, Canada. 139 pp. Bixler, R.B. 1982. Primarypri- mary productivity (Bixler 1982). However, as is theProg Ser 223:133–141 Bixler RP (1982) Primary productivity

  15. Influence of sulfate reducing bacterial biofilm on corrosion behavior of low-alloy, high-strength steel (API-5L X80)

    E-Print Network [OSTI]

    (EIS), polarization resistance (Rp) and open circuit potential (OCP) were used to analyze the corrosion behavior. Through circuit modeling, EIS results were used to interpret the phys- icoelectric interactions

  16. A coupled model study of the remote influence of enso on tropical Atlantic sst variability 

    E-Print Network [OSTI]

    Fang, Yue

    2006-08-16T23:59:59.000Z

    To investigate the tropical Atlantic response to the remote El Nino-Southern Oscillation (ENSO) forcing, a Reduced Physics Â? Coupled Global Circulation Model (RP-CGCM) is developed, and four experiments are carried out. ...

  17. 514 ASHRAE Transactions: Symposia Design cooling load calculation methods are, by the

    E-Print Network [OSTI]

    Handbook--Fundamentals (ASHRAE 1997) and the Cooling and Heating Load Calculation Manual (Mc514 ASHRAE Transactions: Symposia ABSTRACT Design cooling load calculation methods are Load Calculation Methods (942-RP)" are also given. INTRODUCTION Design cooling load calculation

  18. Determining Long-Term Performance of Cool Storage Systems from Short-Term Tests; Literature Review, Preliminary Methodology Description, and Final Site Selection (Final Revision of Nov. 1997 Report)

    E-Print Network [OSTI]

    Reddy, T. A.; Elleson, J.; Haberl, J. S.; Claridge, D. E.

    1998-01-01T23:59:59.000Z

    This preliminary report contains the literature review, a preliminary description of the methodologies that have been chosen for the project and final site selection recommendations for ASHRAE Research Project RP 1004 ~ "Determining Long...

  19. Determining Long-Term Performance of Cool Storage Systems from Short-Term Tests; Literature Review and Site Selection, Nov. 1997 (Revised Feb. 1998)

    E-Print Network [OSTI]

    Haberl, J. S.; Claridge, D. E.; Reddy, T. A.; Elleson, J.

    1997-01-01T23:59:59.000Z

    This is the preliminary report contains the literature review and site selection recommendations for ASHRAE Research Project RP 1004 — "Determining Long-term Performance of Cool Storage Systems From Short-term Tests"....

  20. E:\\CO2\\wp_files\\test_2.PDF

    Office of Scientific and Technical Information (OSTI)

    Technical Conf. On Coal Utilization & Fuel Systems, Coal Technology Assoc., Clear Water, FL by W.K. O'Connor, D.C. Dahlin, D.N. Nilsen, R.P. Walters and P.C. Turner Albany...

  1. Design and Performance Analysis of a Geographic Routing Protocol for Highly Dynamic MANETs

    E-Print Network [OSTI]

    Peters, Kevin James

    2010-06-14T23:59:59.000Z

    forwarding decisions based on neighbor and destination position. The AeroRP geographic routing protocol is detailed, which uses a heuristic metric for forwarding decisions that takes transmission range and a neighbor's location and velocity into consideration...

  2. A PURITY THEOREM FOR FUNCTORS WITH TRANSFERS

    E-Print Network [OSTI]

    ). We show that the following equality holds for the subgroups of the group F(K): pSpec R,htp=1 im for the subgroups of G(K): pSpec R, htp=1 im{G(Rp) G(K)} = im{G(R) G(K)}, () where all maps are induced condition for the functor FR as pSpec R, htp=1 F(Rp) = F(R), ( ) where the left and the right parts

  3. A PURITY THEOREM FOR FUNCTORS WITH TRANSFERS

    E-Print Network [OSTI]

    map). We show that the following equality holds for the subgroups of the group F(K): pSpec R,htp=1 im for the subgroups of G(K): pSpec R, htp=1 im{G(Rp) G(K)} = im{G(R) G(K)}, () where all maps are induced condition for the functor FR as pSpec R, htp=1 F(Rp) = F(R), ( ) where the left and the right parts

  4. LE BULLETIN DE L'EPI N 65 LA ROBOTIQUE PDAGOGIQUE ! LA ROBOTIQUE PDAGOGIQUE !

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    ? Daniel MARCHAND Je rentre justement de Mexico (Mexique) où s'est tenu le "Troisième Congrès International'automate "intelligent". #12;120 Daniel MARCHAND LE BULLETIN DE L'EPI Nombreux sont donc ceux qui pratiquent la R.P. sans/développement en R.P. soute- nue financièrement entre autre par l'APO QUEBEC), jusqu'à l'université où elle est

  5. 1.25-1.75GHZ 1.5 -2.0 GHZ

    E-Print Network [OSTI]

    . SHEET 4) FP FP -10 -10 RP RP 8-T0-1 SWITCH, POL A (SIGNAL SELECTOR FOR PWR METER 2a) 8-T0-1 SWITCH, POL B (SIGNAL SELECTOR FOR PWR METER 2b) FROM AMPS 1-8 POL. B FROM AMPS 1-8 POL. A COUGAR AC582C AMPS 20 RACK 5 COMPUTER READ OUT NOT USED RACK 5 RIGHT HAND PWR METER DUAL-CHANNEL POWER METER #2 HP E4419B

  6. 10/2/2006 SLAC-I-760-2A08Z-001-R002 HAZARDOUS WASTE DETERMINATION FORM

    E-Print Network [OSTI]

    Wechsler, Risa H.

    /2/2006 SLAC-I-760-2A08Z-001-R002 HAZARDOUS WASTE DETERMINATION FORM For RP Use Only Hazardous Waste;________________________________________________________________________________________________ 10/2/2006 SLAC-I-760-2A08Z-001-R002 HAZARDOUS WASTE DETERMINATION FORM For RP Use Only Hazardous Waste Codes:Hazardous Classification: [ ] Non-Hazardous [ ] RCRA Waste [ ] Non-RCRA Waste (CA Haz Waste

  7. Digital Object Identifier (DOI): 10.1007/s00153-004-0246-y

    E-Print Network [OSTI]

    Hrusak, Michael

    -Blass predecessors of p, (4) R(p) - the set of ultrafilters equivalent to p in the strong Rudin-Blass order, (5) PRB ultrafilters p for which PRB (p) = PRK (p), and investigate their relations with P -points, weak- P -points S(p), R(p), T (p), I(p), PRB (p) and PRK (p). We prove that every Frol´ik space is S

  8. The Influence of Vertical Location on Hydraulic Fracture Conductivity in the Fayetteville Shale

    E-Print Network [OSTI]

    Briggs, Kathryn

    2014-05-05T23:59:59.000Z

    companies the ability to compare proppant type and size. To experimentally measure the conductivity of proppant packs in a lab the American Petroleum Institute (API) provided industry with standards for measuring short term conductivity in API RP-61... through the cell at 2 ml/min. and measure the differential pressure and flow rate through the cell giving the values needed to calculate the conductivity. The standards defined in API RP- 61 (1989) are not comparable to actual fracture conductivity due...

  9. 1984 power plant performance monitoring workshop: proceedings

    SciTech Connect (OSTI)

    Not Available

    1986-05-01T23:59:59.000Z

    An EPRI workshop on fossil plant performance monitoring and improvement was conducted in Washington, DC, October 23-25, 1984. The main theme of the workshop was the EPRI-PEPCo performance monitoring project (EPRI projects RP1681 and RP2153) highlighted in the opening session. The objective of this project is to develop an advanced instrumentation and monitoring system to improve heat rate, recover lost capacity, optimize system dispatch, and plan maintenance more effectively. Interim results of this project, which can now be used by the utility industry, were emphasized in the presentations including (1) the boiler parametric analysis program for optimizing boiler combustion efficiency and (2) the N2 packing monitor that measures the steam leakage from the high-pressure to the intermediate-pressure turbine. Other EPRI projects, such as RP1711-2 and RP1878-1, were also highlighted. RP1711-2 employs root-cause investigation techniques to trace plant heat-rate degradation problems and recommend cost-effective solutions, while RP1878-1 introduces a nonradioactive tracer technique to monitor turbine efficiency. Twenty-seven papers have been entered individually into EDB and ERA. Section 6 - working group minutes - was not entered by itself. (LTN)

  10. Secretary Abraham Announces Energy Department "What's Next" Expo...

    Broader source: Energy.gov (indexed) [DOE]

    and the lead researcher in a DOE-funded project designed to help restore sight for blind people affected by retinal disorders. Students then toured the nearly 50 interactive...

  11. Probabilistic Models of Phase Variables for Visual Representation and Neural Dynamics

    E-Print Network [OSTI]

    Cadieu, Charles

    2009-01-01T23:59:59.000Z

    87(6):2715, 2002. [Bulow and Sommer, 2001] T.Bulow and G. Sommer. Hypercomplex signals-a novel exten-J.A. Hirsch, and F.T. Sommer. Retinal oscillations carry

  12. anterior motor evoked: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    old, 12-month old, and adult) based on auditory event-related potentials Reilly, James P. 124 CellularMolecular Calcium Increases in Retinal Glial Cells Evoked by Light-...

  13. afferent neurons evoked: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    old, 12-month old, and adult) based on auditory event-related potentials Reilly, James P. 177 CellularMolecular Calcium Increases in Retinal Glial Cells Evoked by Light-...

  14. Realization of a 15-channel, hermetically-encased wireless subretinal for the blind

    E-Print Network [OSTI]

    Wyatt, John L.

    A miniaturized, hermetically-encased, wirelessly-operated retinal prosthesis has been developed for implantation and pre-clinical studies in Yucatan mini-pig animal models. The prosthesis conforms to the eye and drives a ...

  15. haler, Eds., vol. 16 of Lecture Notes in Earth Sciences (Springer-Verlag, New York, 1988), pp. 83116.

    E-Print Network [OSTI]

    Hahn, Mark E.

    . The protein was functionally expressed in Escherichia coli and bound retinal to form an active, light of naturally occuring marine bacterioplankton. The bacterial rhodopsin was encoded in the genome

  16. In vivo operation of the Boston 15-channel wireless subretinal visual prosthesis

    E-Print Network [OSTI]

    Wyatt, John L.

    This presentation concerns the engineering development of the Boston visual prosthesis for restoring useful vision to patients blind with degenerative retinal disease. A miniaturized, hermetically-encased, 15-channel ...

  17. Precision and reliability of cochlear nerve response in mice lacking functional synaptic ribbons

    E-Print Network [OSTI]

    Buran, Bradley N. (Bradley Nicholas)

    2009-01-01T23:59:59.000Z

    Synaptic ribbons are electron-dense structures surrounded by vesicles and anchored to the presynaptic membrane of photoreceptors, retinal bipolar cells and hair cells. Ribbon synapses are characterized by sustained exocytosis ...

  18. A system for efficient neural stimulation with energy recovery

    E-Print Network [OSTI]

    Kelly, Shawn Kevin, 1973-

    2004-01-01T23:59:59.000Z

    An analog VLSI-based low-power neural tissue stimulator is presented as a part of the MIT and Massachusetts Eye and Ear Infirmary Retinal Implant Project to develop a prosthesis for restoring some useful vision to patients ...

  19. Characterization of the Structure and Function of the Normal Human Fovea Using Adaptive Optics Scanning Laser Ophthalmoscopy

    E-Print Network [OSTI]

    Putnam, Nicole Marie

    2012-01-01T23:59:59.000Z

    MEMS: MTF: OCT: OS: OTF: PFD: PRL: PSF: RMS: SHWS: SLD: SNR:retinal locus of fixation (PRL), where many samples of theWe measure both the PRL and the PFD on two separate days and

  20. Imaging the foveal cone mosaic with a MEMS-based adaptive optics scanning laser ophthalmoscope

    E-Print Network [OSTI]

    Li, Yiang

    2010-01-01T23:59:59.000Z

    function of axial length at the PRL Results from running theIPT LQ LQR MEMS OCT OPD PID PRL PSD PSF PSI RMF RMS RPE SLDpreferred retinal locus (PRL), and the scan angle was 1°. An

  1. The Microscopic Linear Dynamics

    E-Print Network [OSTI]

    Penny, Will

    The Microscopic Brain Will Penny Linear Dynamics Exponentials Matrix Exponential Eigendecomposition Dynamical Modes Nodes State Space Saddles Oscillations Spirals Centres Offsets Retinal Circuit Nullclines Stability Spiking Neurons Fitzhugh-Nagumo Nonlinear Dynamics Linearization Nonlinear Oscillation Excitable

  2. Metatranscriptomic and physiological analyses of proteorhodopsin-containing marine flavobacteria

    E-Print Network [OSTI]

    Kim, Hana, S.M. Massachusetts Institute of Technology

    2013-01-01T23:59:59.000Z

    Proteorhodopsin (PR) is a seven-helix integral membrane protein that uses retinal as a chromophore. PRs transport protons from the cytoplasmic (CP) to the extracellular (EC) side of the cell membrane utilizing the energy ...

  3. Accepted Manuscript Comment on "Ccl2, Cx3cr1 and Ccl2/Cx3cr1 chemokine deficiencies are not sufficient

    E-Print Network [OSTI]

    Boyer, Edmond

    Accepted Manuscript Comment on "Ccl2, Cx3cr1 and Ccl2/Cx3cr1 chemokine deficiencies on "Ccl2, Cx3cr1 and Ccl2/Cx3cr1 chemokine deficiencies are not sufficient to cause age- related retinal on "Ccl2, Cx3cr1 and Ccl2/Cx3cr1 chemokine deficiencies are not sufficient to cause age- related retinal

  4. Association Between White Blood Cell Count Following Radiation Therapy With Radiation Pneumonitis in Non-Small Cell Lung Cancer

    SciTech Connect (OSTI)

    Tang, Chad; Gomez, Daniel R. [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Wang, Hongmei [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou (China); Levy, Lawrence B. [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Zhuang, Yan [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Xu, Ting; Nguyen, Quynh; Komaki, Ritsuko [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Liao, Zhongxing, E-mail: zliao@mdanderson.org [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States)

    2014-02-01T23:59:59.000Z

    Purpose: Radiation pneumonitis (RP) is an inflammatory response to radiation therapy (RT). We assessed the association between RP and white blood cell (WBC) count, an established metric of systemic inflammation, after RT for non-small cell lung cancer. Methods and Materials: We retrospectively analyzed 366 patients with non-small cell lung cancer who received ?60 Gy as definitive therapy. The primary endpoint was whether WBC count after RT (defined as 2 weeks through 3 months after RT completion) was associated with grade ?3 or grade ?2 RP. Median lung volume receiving ?20 Gy (V{sub 20}) was 31%, and post-RT WBC counts ranged from 1.7 to 21.2 × 10{sup 3} WBCs/?L. Odds ratios (ORs) associating clinical variables and post-RT WBC counts with RP were calculated via logistic regression. A recursive-partitioning algorithm was used to define optimal post-RT WBC count cut points. Results: Post-RT WBC counts were significantly higher in patients with grade ?3 RP than without (P<.05). Optimal cut points for post-RT WBC count were found to be 7.4 and 8.0 × 10{sup 3}/?L for grade ?3 and ?2 RP, respectively. Univariate analysis revealed significant associations between post-RT WBC count and grade ?3 (n=46, OR=2.6, 95% confidence interval [CI] 1.4?4.9, P=.003) and grade ?2 RP (n=164, OR=2.0, 95% CI 1.2?3.4, P=.01). This association held in a stepwise multivariate regression. Of note, V{sub 20} was found to be significantly associated with grade ?2 RP (OR=2.2, 95% CI 1.2?3.4, P=.01) and trended toward significance for grade ?3 RP (OR=1.9, 95% CI 1.0-3.5, P=.06). Conclusions: Post-RT WBC counts were significantly and independently associated with RP and have potential utility as a diagnostic or predictive marker for this toxicity.

  5. Serum Amyloid A as a Predictive Marker for Radiation Pneumonitis in Lung Cancer Patients

    SciTech Connect (OSTI)

    Wang, Yu-Shan [Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China) [Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China); Department of Animal Science, National Ilan University, Ilan, Taiwan (China); Chang, Heng-Jui [Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China)] [Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China); Chang, Yue-Cune [Department of Mathematics, Tamkang University, Taipei, Taiwan (China)] [Department of Mathematics, Tamkang University, Taipei, Taiwan (China); Huang, Su-Chen; Ko, Hui-Ling; Chang, Chih-Chia [Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China)] [Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China); Yeh, Yu-Wung; Jiang, Jiunn-Song [Department of Chest Medicine, Shin-Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China)] [Department of Chest Medicine, Shin-Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China); Lee, Cheng-Yen; Chi, Mau-Shin [Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China)] [Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China); Chi, Kwan-Hwa, E-mail: M006565@ms.skh.org.tw [Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China) [Department of Radiation Therapy and Oncology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China); Institute of Radiation Science and School of Medicine, National Yang-Ming University, Taipei, Taiwan (China)

    2013-03-01T23:59:59.000Z

    Purpose: To investigate serum markers associated with radiation pneumonitis (RP) grade ?3 in patients with lung cancer who were treated with radiation therapy. Methods and Materials: Pretreatment serum samples from patients with stage Ib-IV lung cancer who developed RP within 1 year after radiation therapy were analyzed to identify a proteome marker able to stratify patients prone to develop severe RP by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF-MS). Dosimetric parameters and 3 biological factors were compared. Results: Serum samples from 16 patients (28%) with severe RP (grade 3-4) and 42 patients (72%) with no or mild RP (grade 0-2) were collected for analysis. All patients received a median of 54 Gy (range, 42-70 Gy) of three-dimensional conformal radiation therapy with a mean lung dose (MLD) of 1502 cGy (range, 700-2794 cGy). An m/z peak of 11,480 Da was identified by SELDI-TOF-MS, and serum amyloid A (SAA) was the primary splitter serum marker. The receiver operating characteristic area under the curve of SAA (0.94; 95% confidence interval [CI], 0.87-1.00) was higher than those of C-reactive protein (0.83; 95% CI, 0.72-0.94), interleukin-6 (0.79; 95% CI, 0.65-0.94), and MLD (0.57; 95% CI, 0.37-0.77). The best sensitivity and specificity of combined SAA and MLD for predicting RP were 88.9% and 96.0%, respectively. Conclusions: Baseline SAA could be used as an auxiliary marker for predicting severe RP. Extreme care should be taken to limit the lung irradiation dose in patients with high SAA.

  6. Transonic throat flow in radial or nearly radial supersonic nozzles

    E-Print Network [OSTI]

    Carroll, Bruce Frederick

    1984-01-01T23:59:59.000Z

    , /D = O(s ' ') x=0(c' ) v = 0(c' ') u = O(c) (22) With these order of magnitude estimates, the following 0(1) quantities are defined i y+1) Rp p/p 2j 0' I 2 ) sing -p/p 0& = m I ?e Cp [y+J) Rp/D mcosf ~Rp D (23) gp = g (0)c P hq ? ~~ h...) = hg Ap (-1) = gi AI (1) = hz A~ (-1) = gz (45) Substituting the assumed solution for vl(z, y), Eq. (44), into the irrotationality condition, Eq. (26), and integrating with respect to y gives ul (z, y) as uq (z, y) = A& (y) + Bo + (46) where B...

  7. Functional Promoter Variant rs2868371 of HSPB1 Is Associated With Risk of Radiation Pneumonitis After Chemoradiation for Non-Small Cell Lung Cancer

    SciTech Connect (OSTI)

    Pang, Qingsong [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center (United States) [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center (United States); Department of Radiation Oncology and Lung Cancer Center, Tianjin Medical University Cancer Institute and Hospital, Key Laboratory of Cancer Prevention and Therapy, Tianjin (China); Wei, Qingyi [Department of Epidemiology, The University of Texas MD Anderson Cancer Center (United States)] [Department of Epidemiology, The University of Texas MD Anderson Cancer Center (United States); Xu, Ting [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center (United States)] [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center (United States); Yuan, Xianglin [Department of Oncology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan (China)] [Department of Oncology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan (China); Lopez Guerra, Jose Luis [Department of Medicine, Universitat Autònoma de Barcelona (Spain)] [Department of Medicine, Universitat Autònoma de Barcelona (Spain); Levy, Lawrence B. [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center (United States)] [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center (United States); Liu, Zhensheng [Department of Epidemiology, The University of Texas MD Anderson Cancer Center (United States)] [Department of Epidemiology, The University of Texas MD Anderson Cancer Center (United States); Gomez, Daniel R. [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center (United States)] [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center (United States); Zhuang, Yan [Department of Radiation Physics, The University of Texas MD Anderson Cancer Center (United States)] [Department of Radiation Physics, The University of Texas MD Anderson Cancer Center (United States); Wang, Li-E. [Department of Epidemiology, The University of Texas MD Anderson Cancer Center (United States)] [Department of Epidemiology, The University of Texas MD Anderson Cancer Center (United States); Mohan, Radhe [Department of Radiation Physics, The University of Texas MD Anderson Cancer Center (United States)] [Department of Radiation Physics, The University of Texas MD Anderson Cancer Center (United States); Komaki, Ritsuko [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center (United States)] [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center (United States); Liao, Zhongxing, E-mail: zliao@mdanderson.org [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center (United States)] [Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center (United States)

    2013-04-01T23:59:59.000Z

    Purpose: To date, no biomarkers have been found to predict, before treatment, which patients will develop radiation pneumonitis (RP), a potentially fatal toxicity, after chemoradiation for lung cancer. We investigated potential associations between single nucleotide polymorphisms (SNPs) in HSPB1 and risk of RP after chemoradiation for non-small cell lung cancer (NSCLC). Methods and Materials: Subjects were patients with NSCLC treated with chemoradiation at 1 institution. The training data set comprised 146 patients treated from 1999 to July 2004; the validation data set was 125 patients treated from August 2004 to March 2010. We genotyped 2 functional SNPs of HSPB1 (rs2868370 and rs2868371) from all patients. We used Kaplan-Meier analysis to assess the risk of grade ?2 or ?3 RP in both data sets and a parametric log-logistic survival model to evaluate the association of HSPB1 genotypes with that risk. Results: Grade ?3 RP was experienced by 13% of those with CG/GG and 29% of those with CC genotype of HSPB1 rs2868371 in the training data set (P=.028); corresponding rates in the validation data set were 2% CG/GG and 14% CC (P=.02). Univariate and multivariate analysis confirmed the association of CC of HSPB1 rs2868371 with higher risk of grade ?3 RP than CG/GG after adjustment for sex, age, performance status, and lung mean dose. This association was validated both in the validation data set and with Harrell's C statistic. Conclusions: The CC genotype of HSPB1 rs2868371 was associated with severe RP after chemoradiation for NSCLC.

  8. Control of linear modes in cylindrical resistive magnetohydrodynamics with a resistive wall, plasma rotation, and complex gain

    SciTech Connect (OSTI)

    Brennan, D. P. [Department of Astrophysical Sciences, Princeton University, Princeton, New Jersey 08544 (United States); Finn, J. M. [Applied Mathematics and Plasma Physics, Theoretical Division, Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States)

    2014-10-15T23:59:59.000Z

    Feedback stabilization of magnetohydrodynamic (MHD) modes in a tokamak is studied in a cylindrical model with a resistive wall, plasma resistivity, viscosity, and toroidal rotation. The control is based on a linear combination of the normal and tangential components of the magnetic field just inside the resistive wall. The feedback includes complex gain, for both the normal and for the tangential components, and it is known that the imaginary part of the feedback for the former is equivalent to plasma rotation [J. M. Finn and L. Chacon, Phys. Plasmas 11, 1866 (2004)]. The work includes (1) analysis with a reduced resistive MHD model for a tokamak with finite ? and with stepfunction current density and pressure profiles, and (2) computations with a full compressible visco-resistive MHD model with smooth decreasing profiles of current density and pressure. The equilibria are stable for ??=?0 and the marginal stability values ?{sub rp,rw}?rp,iw} rp,iw} because rotation suppresses the diffusion of flux from the plasma out through the wall and, more surprisingly, (b) rotation or imaginary gain with normal sensors destabilizes above ?{sub rp,iw} because it prevents the feedback flux from entering the plasma through the resistive wall to form a virtual wall. A method of using complex gain G{sub i} to optimize in the presence of rotation in this regime with ??>??{sub rp,iw} is presented. The effect of imaginary gain with tangential sensors is more complicated but essentially destabilizes above and below ?{sub rp,iw}.

  9. Methodology Development for Determining Long-Term Performance of Cool Storage Systems from Short-Term Tests

    E-Print Network [OSTI]

    Reddy, T.A.; Elleson, J.S.; Haberl, J.S.

    . For example, if storage is used to shift load year-round, ml=1 and m2=12. particular period during the day/week/year Analysis with Short Data Sets A few studies discussed in the RP-l004 literature review (Reddy et al. 1998b) investigated the annual predictive... temperature-dependent regres­ sion models of energy use identified from short data sets are AC-02-19-3 (RP-1004) ESL-PA-02-01-02 able to predict annual energy use has been investigated with monitored data by Kissock et al. (1998) for two-parameter single...

  10. Subgenomic promoter recognition by the norovirus RNA-dependent RNA polymerases

    E-Print Network [OSTI]

    Lin, Xiaoyan; Thorne, Lucy; Jin, Zhinan; Hammad, Loubna A.; Li, Serena; Deval, Jerome; Goodfellow, Ian G.; Kao, C. Cheng

    2014-12-17T23:59:59.000Z

    Rp in the presence of increasing concentrations of three competitor RNAs, Chp, Ghp and Mhp. Comparable results were obtained in three independent experiments. (E) Deletions in the hairpin within Mps severely reduced de novo initiated RNA synthesis. The gel image... RdRp in the presence of increasing concentrations of three competitor RNAs, Chp, Ghp and Mhp. at U niversity of Cam bridge on February 11, 2015 http://nar.oxfordjournals.org/ D ow nloaded from Nucleic Acids Research, 2014 7 We sought to determine...

  11. Pollak and Wachter on the Household Production Function Approach

    E-Print Network [OSTI]

    Barnett, William A.

    1977-10-01T23:59:59.000Z

    of the ith commodity. As Pollak and Wachter have observed, much of the appeal of the commodity shadow-price approach lies in its ability to use functions having known neoclassical properties. However, Pollak and Wachter maintain that, if the constraint 7r(P...). But the commodity shadow prices 7r(P, Z) do depend upon Z whenever house- hold production exhibits jointness, which Pollak and Wachter maintain is inherently characteristic of household production processes. Hence 1 Pollack and Wachter have considered...

  12. Operational Radiation Protection in High-Energy Physics Accelerators

    SciTech Connect (OSTI)

    Rokni, S.H.; Fasso, A.; Liu, J.C.; /SLAC

    2012-04-03T23:59:59.000Z

    An overview of operational radiation protection (RP) policies and practices at high-energy electron and proton accelerators used for physics research is presented. The different radiation fields and hazards typical of these facilities are described, as well as access control and radiation control systems. The implementation of an operational RP programme is illustrated, covering area and personnel classification and monitoring, radiation surveys, radiological environmental protection, management of induced radioactivity, radiological work planning and control, management of radioactive materials and wastes, facility dismantling and decommissioning, instrumentation and training.

  13. Quantum models with spectrum generated by the flows of polynomial zeros

    E-Print Network [OSTI]

    Alexander Moroz

    2014-10-27T23:59:59.000Z

    A class {\\cal R}_p of purely bosonic models is characterized having the following properties in the Bargmann Hilbert space of analytic functions: (i) wave function \\psi(\\epsilon,z)=\\sum_{n=0}^\\infty \\phi_n(\\epsilon) z^n is the {\\em generating function} for orthogonal polynomials \\phi_n(\\epsilon) of a discrete energy variable \\epsilon, (ii) any Hamiltonian \\hat{H}_b\\in {\\cal R}_p has nondegenerate purely point spectrum that corresponds to infinite discrete support of measure d\

  14. Development of a fast neutron therapy beam placement film technique 

    E-Print Network [OSTI]

    Baron, Robert Layton

    1971-01-01T23:59:59.000Z

    by the fibro sarcoma. . . . . . . . . . . . . . . . . . ~ 31 32 39 40 Figure 10. This roentgenograph of subject OA276 shows the position of the Pb-covered stint used in skin-sparing experiments. 11. The head of Dog FOA276 shows good contrast between... was 9. 8 rads. 45 14. This screened placement film of Candy required only a 0. 88 rad dose on Kodak RP-14 film. 46 15. Dog FOA272 was the subject of this 0. 62 rad dose, CaWO screened placement film on Kodak RP-14 film. . . 47 4 16. This placement...

  15. Condensate polishers for brackish water-cooled PWRs

    SciTech Connect (OSTI)

    Sadler, M.A.; Darvill, M.R.; Bickerstaffe, J.A.; Chakravorti, R.; Siegwarth, D.P.

    1986-07-01T23:59:59.000Z

    The objectives of project RP 1571-5 ''Optimization of Pressurized Water Reactor Secondary Water Treatment: Task 4 Conceptual Design Options - Condensate Polishing'' were to provide detailed guidelines for the design of a condensate polishing system for retrofitting to a seawater cooled PWR. For this purpose a national 1100MW PWR with recirculating steam generators was defined. The polished water to be produced by this plant must be of such a quality so as to permit the advisory SGOG guidelines on impurity levels in Steam Generator water to be achieved. Target maximum impurity levels in the final polished water were proposed by the RP 1571 Project review Team and adopted for this study.

  16. Detection of azimuthal anisotropy from 3-D p-wave seismic data

    E-Print Network [OSTI]

    Yildizel, Ali

    1992-01-01T23:59:59.000Z

    the equation; (II ? 1) for u(z) = V t(z) is wave slowness. Velocity estimation using reflections and the tau-p approach was first suggested by Schultz and Claerbout (1978), They showed that velocity analysis can be done in a ' similar manner... to conventional analysis by looking for maximum coherency over each ' trajectory of ellipses in r-p domain instead of a hyperbola in conventional analysis. Schultz (1982) also suggested a method of layer-stripping for velocity estimation in the r-p domain...

  17. WSSRAP chemical plant geotechnical investigations for the Weldon Spring Site Remedial Action Project, Weldon Spring, Missouri

    SciTech Connect (OSTI)

    Not Available

    1990-12-01T23:59:59.000Z

    This document has been prepared for the United states Department of Energy (DOE) Weldon Spring Site Remedial Action Project (WSSRAP) by the Project Management Contractor (PMC), which consists of MK-Ferguson Company (MKF) and Morrison Knudsen Corporation Environmental Services Group (MKES) with Jacobs Engineering Group (JEG) as MKF's predesignated subcontractor. This report presents the results of site geotechnical investigations conducted by the PMC in the vicinity of the Weldon Spring chemical plant and raffinate pits (WSCP/RP) and in potential on-site and off-site clayey material borrow sources. The WSCP/RP is the proposed disposal cell (DC) site. 39 refs., 24 figs., 12 tabs.

  18. Biocompatible implants and methods of making and attaching the same

    DOE Patents [OSTI]

    Rowley, Adrian P; Laude, Lucien D; Humayun, Mark S; Weiland, James D; Lotfi, Atoosa; Markland, Jr., Francis S

    2014-10-07T23:59:59.000Z

    The invention provides a biocompatible silicone implant that can be securely affixed to living tissue through interaction with integral membrane proteins (integrins). A silicone article containing a laser-activated surface is utilized to make the implant. One example is an implantable prosthesis to treat blindness caused by outer retinal degenerative diseases. The device bypasses damaged photoreceptors and electrically stimulates the undamaged neurons of the retina. Electrical stimulation is achieved using a silicone microelectrode array (MEA). A safe, protein adhesive is used in attaching the MEA to the retinal surface and assist in alleviating focal pressure effects. Methods of making and attaching such implants are also provided.

  19. WATER RESOURCES NEWS NEBRASKA WATER RESOURCES RESEARCH INSTITUTE

    E-Print Network [OSTI]

    Nebraska-Lincoln, University of

    WATER RESOURCES NEWS NEBRASKA WATER RESOURCES RESEARCH INSTITUTE 212 AGRICULTURAL ENGINEERING OF THE DIRECTOR . . . April 1973 NEBRASKA AND THE NATIONAL WATER COMMISSION REPORT The National Water Commission grew out of con t r-ovc rey over water resource deve lopment in the Colorado River Basin. Rp

  20. Strategies for abbreviating multiple word titles 

    E-Print Network [OSTI]

    Takao, Alan Clay

    1993-01-01T23:59:59.000Z

    HLED [IHEDU i]HLTH I~ETEC IIFD'IC IIEDUI' ] ['f'CH [] ET I I EDTE 11. RECREATION AND PARKS I ] RP I I REPK f I RFCP I I RECR [ f RPKS i)REPA 12. SAFETY ENGINEER)NO [)SAFE IISENG IISEGR I[BE (] SAEN I I SFTY Figure A2. Encoding page (example) used...

  1. Sustainable Energy Research Team publications Whittaker, C., Adams, P., McManus, M.C Securing a Bioenergy Supply: UK and US in

    E-Print Network [OSTI]

    Martin, Ralph R.

    .C Securing a Bioenergy Supply: UK and US in Perspectives on Biofuels: Potential Benefits and Possible case studies. World Renewable Energy Congress. Sweden, May 8 ­ 13 · Griffin, P.W., Hammond, G.P., Ng, R.P. (2011) Greenhouse gas reporting for biofuels: A comparison between the RED, RTFO and PAS2050

  2. Parity Violation in Photonuclear Reactions at HIGS Submission to Fundamental Symmetries and Neutrino Physics Working Group

    E-Print Network [OSTI]

    and Neutrino Physics Working Group H. Gao,1 S.S. Jawalker,1 M.R. Schindler,2 W.M. Snow,3 R.P. Springer,1 and Ying Wu1 1 Department of Physics, Duke University, Durham, NC 27708, USA 2 Department of Physics; W. Xu*, Shanghai Institute of Applied Physics; Shi-Lin Zhu, Peking U; * to be confirmed I

  3. Texas Tech University Energy Conservation Plan -Quarterly Update

    E-Print Network [OSTI]

    Gelfond, Michael

    Texas Tech University Energy Conservation Plan - Quarterly Update April 2006 Executive Order RP-49 from the Governor's Office requires each state agency to develop an energy conservation plan and set Plan, reporting to the State Energy Conservation Office (SECO) is the two-year energy reduction goal

  4. Environmental proxies of antigen exposure explain variation in immune investment better than indices of pace of life

    E-Print Network [OSTI]

    Horrocks, Nicholas P. C.; Hegemann, Arne; Ostrowski, Stéphane; Ndithia, Henry; Shobrak, Mohammed; Williams, Joseph B.; Matson, Kevin D.; Tieleman, B. Irene

    2014-11-11T23:59:59.000Z

    "RP,"Harvey"PH,"Pagel"M"(2002)"Phylogenetic"analysis"and"comparative"data:"A"360" test"and"review"of"evidence."Am"Nat"160:"712`726"doi:"10.1086/343873"361" Froeschke"G,"Harf"R,"Sommer"S,"Matthee"S"(2010)"Effects"of"precipitation"on"parasite"burden"362" along"a"natural"climatic...

  5. Assessment of seismic risk for subsea production systems in the Gulf of Mexico

    E-Print Network [OSTI]

    Brown, Laura Ann

    2004-09-30T23:59:59.000Z

    The number of subsea production systems placed in deepwater locations in the Gulf of Mexico (GOM) has increased significantly in the last ten to fifteen years. Currently, API-RP2A (2000 a,b) designates the GOM as a low seismic zone, and thus does...

  6. Determining Long-Term Performance of Cool Storage Systems from Short-Term Tests, Final Report

    E-Print Network [OSTI]

    Reddy, T. A.; Elleson, J.; Haberl, J. S.

    2000-01-01T23:59:59.000Z

    This is the final report for ASHRAE Research Project 1004-RP: Determining Long-Term Performance of Cool Storage Systems from Short-Term Tests. This report presents the results of the development and application of the methodology to Case Study #2...

  7. Fractal images induce fractal pupil dilations and constrictions

    E-Print Network [OSTI]

    Taylor, Richard

    1 Fractal images induce fractal pupil dilations and constrictions P. Moon, J. Muday, S. Raynor, J. Schirillo Wake Forest University C. Boydston, M. S. Fairbanks, R.P. Taylor University of Oregon Fractals revealed fractal patterns in many natural and physiological processes. This article investigates pupillary

  8. PhD theses completed within the GPRG For further details of any thesis listed here, please contact Martin Fox

    E-Print Network [OSTI]

    Sheffield, University of

    utilising culture Sponsored by: Shell International Oil Products (UK) Beiyan Zhang Modelling groundwater of Birmingham) R.J. Andrews, 1993 The impact of sewage sludge application on nitrate leaching from arable land of Birmingham). R.P. Ashley, 1991 Mechanisms controlling oil behaviour in the unsaturated Chalk (Ph

  9. SUCCESS IS NOT GUARANTEED bridges vol. 27, October 2010 / Pielke's Perspective

    E-Print Network [OSTI]

    Colorado at Boulder, University of

    , policy should focus on bringing down the cost of alternatives. Hence my focus is on policies as India and Germany. India has set a 50 rp tax per tonne of coal in order to raise more than $500 million for certainty in policy proposals. One line of critique expresses frustration that the technology-led approach

  10. Optical and Mechanical Effects of Elastomeric Distributed Bragg Reflectors

    E-Print Network [OSTI]

    Kamita, Gen

    2014-05-27T23:59:59.000Z

    .59) will give the true stress t: t1 = t2 = F A = piR2?P 2piRH = R?P 2H . (2.60) Equation 2.60 can be used to analyse the stress and strain of spherical balloons, or of any thin membrane/wall with a spherical curvature under pressure difference, including boilers...

  11. Beam optics and the pp2pp experiment at RHIC

    SciTech Connect (OSTI)

    Pile P. H.; Guryn, W.; Lee, J.H.; Tepikian, S.; Yip, K.

    2012-05-20T23:59:59.000Z

    The newly installed forward detector system at the STAR experiment at RHIC measures small angle elastic and inelastic scattering of polarized protons on polarized protons. The detector system makes use of a pair of Roman Pot (RP) detectors, instrumented with silicon detectors, and located on either side of the STAR intersection region downstream of the DX and D0 dipoles and quadrupole triplets. The parallel to point optics is designed so that scattering angles are determined from position measurements at the RP's with small error. The RP setup allows measurement of position and angle for a subset of the scattered protons. With this position/angle correlations at the RP's can be compared with optics model predictions to get a measure of the accuracy of the quadrupole triplet current settings. The current in each quadrupole in the triplets is comprised of sums and differences of up to six power supplies and an overall 1% error in the triplet field strengths results in a 4% error in four-momentum transfer squared. This technique is also useful to check the polarity of the skew elements located in each quadrupole triplet. Results of the analysis will be presented.

  12. FUEL CELL SYSTEM ECONOMICS: COMPARING THE COSTS OF GENERATING POWER WITH STATIONARY

    E-Print Network [OSTI]

    Kammen, Daniel M.

    FUEL CELL SYSTEM ECONOMICS: COMPARING THE COSTS OF GENERATING POWER WITH STATIONARY AND MOTOR VEHICLE PEM FUEL CELL SYSTEMS UCD-ITS-RP-04-21 April 2004 by Timothy Lipman University of California: itspublications@ucdavis.edu #12;Energy Policy 32 (2004) 101­125 Fuel cell system economics: comparing the costs

  13. Kitkahahki Chipped Stone Technologies: A Comparative Study

    E-Print Network [OSTI]

    Asher, Brendon Patrick

    2009-06-11T23:59:59.000Z

    , and the increasingly pervasive influence of new technologies on traditional life-ways. Here I consider the chipped stone material from two Kitkehahki Pawnee sites, 14RP1 in Republic County, Kansas, and the Hill site (25WT1) in Webster County, Nebraska. Stone sources...

  14. Image credit: NASA/Dana Berr X-ray bursts

    E-Print Network [OSTI]

    Greenaway, Alan

    and density conditions (T > 109 K, ~ 106 g/cm3) - Thermonuclear runaway © David A. Hardy/www.astroart.org #12.E., 1993, Sp Sci Rev, 62, 223 #12;Producing exotic rp-nuclei - Compound nucleus formed in fusion reaction - Mass A=62 fusion evaporation products analysed at 0o by Argonne FMA Argonne 24Mg Target 40Ca beam #12

  15. Laboratory Study to Identify the Impact of Fracture Design Parameters over the Final Fracture Conductivity Using the Dynamic Fracture Conductivity Test Procedure

    E-Print Network [OSTI]

    Pieve La Rosa, Andres Eduardo

    2011-08-08T23:59:59.000Z

    , fines, and dried polymer over the core surface ......................................................................................... 67 Fig. 3.17 Common indentation marks over cores surface after proppant was removed....3 respectively over the conductivity. The American Petroleum Institute developed and published recommended practice guidelines known as API RP 61 (1989); this recommended practice describes how to obtain the conductivity of proppant using a conductivity cell...

  16. Modeling and Designing Network Defense against Control Channel Jamming Attacks: A

    E-Print Network [OSTI]

    Poovendran, Radha

    . Keywords: Cyber-physical system, Node capture attacks, Security, Control- channel jamming, Passivity 1, University of Washington, Seattle, WA, 98195, USA {leep3, awclark, lb2, rp3}@uw.edu Abstract. Cyber-physical systems rely on distributed embedded wire- less nodes for sensing, computation, and control, often leaving

  17. Quantitative and Qualitative Determination of Polysulfide Species in the Electrolyte of a Lithium-Sulfur Battery using HPLC ESI/MS with One-Step Derivatization

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Zheng, Dong [Department of Chemistry; University of Massachusetts Boston; Boston MA 02125 USA; Qu, Deyu [Wuhan Univ. of Technology, Wuhan (China). Dept. of Chemistry; Yang, Xiao-Qing [Brookhaven National Lab. (BNL), Upton, NY (United States). Dept. of Chemistry; Yu, Xiqian [Brookhaven National Lab. (BNL), Upton, NY (United States). Dept. of Chemistry; Lee, Hung-Sui [Brookhaven National Lab. (BNL), Upton, NY (United States). Dept. of Chemistry; Qu, Deyang [Univ. of Massachusetts, Boston, MA (United States). Dept. of Chemistry

    2015-01-01T23:59:59.000Z

    The polysulfide species dissolved in aprotic solvents can be separated and analyzed by reverse phase (RP) high performance liquid chromatography (HPLC) in tandem with electrospray-mass spectroscopy. The relative distribution of polysulfide species in the electrolyte recovered from Li-S batteries is quantitatively and reliably determined for the first time.

  18. Comparisons of numerical modelling of the Selective Laser Melting Laurent VAN BELLE1, 2, a

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    and arc additive layer manufacturing (WAALM), laser metal deposition (LMD), selective laser melting (SLM laser melting (SLM) first developed for rapid prototyping (RP) is now used for rapid manufacturing is based upon a double meshing with a multi step birth and death technique of manufactured part

  19. National Centre for Earth Observation, Publications 2008 National Centre for Earth Observation Publications 2008

    E-Print Network [OSTI]

    :213, British Geological Survey Report no. CR/08/179, 48pp. Aiken, J., Hardman-Mountford, N.J., Barlow remote sensing. Journal of Plankton Research 30: 165-182. Allan, R.P. and Soden, B.J. (2008) Atmospheric. Bösch, S.C. Doney, and D.S. Schimel, (2008) Carbon source/sink information provided by column CO2

  20. Brayton Cycles: From the ...rst law, the maximum transfers for component SSSF control volumes are

    E-Print Network [OSTI]

    . For the simple reversible Brayton cycle of given pressure ratio rp $ (p2=p1) = (p3=p4) [compare Example 9.4, pp is higher than 1 r (2=7) . For the ideal regenerator, the thermal e¢ ciency approaches the Carnot-cycle eBrayton Cycles: From the ...rst law, the maximum transfers for component SSSF control volumes are w

  1. Ocean and Sea Ice SAF ASCAT-B NWP Ocean Calibration

    E-Print Network [OSTI]

    Haak, Hein

    Ocean and Sea Ice SAF ASCAT-B NWP Ocean Calibration and Validation Technical Report SAF/OSI/CDOP2 #12;SAF/OSI/CDOP2/KNMI/TEC/RP/199 ASCAT-B NWP Ocean Calibration and Validation Summary On September 17 launched. For the ASCAT-B scatterometer, corrections are derived with the use of the NWP ocean calibration

  2. RAPID COMMUNICATIONS PHYSICAL REVIEW B 84, 121410(R) (2011)

    E-Print Network [OSTI]

    2011-01-01T23:59:59.000Z

    RAPID COMMUNICATIONS PHYSICAL REVIEW B 84, 121410(R) (2011) Pairing in graphene: A quantum Monte superconductivity in graphene, we perform a systematic quantum Monte Carlo study of the pairing correlation in the t.10.Fd, 74.70.Wz, 74.20.Mn, 74.20.Rp Recently, graphene has attracted the attention of experimen- talists

  3. Copyright 2004 by the Genetics Society of America DOI: 10.1534/genetics.104.032656

    E-Print Network [OSTI]

    Craig, Elizabeth A

    , heat shock, assembled from four rRNAs and 80 ribosomal proteins. oxidization, or osmotic stress, all and Biochemical Interactions Among Yar1, Ltv1 and RpS3 Define Novel Links Between Environmental Stress. In this study we show that two nonessential stress-responsive genes, YAR1 and LTV1, function in 40S subunit

  4. Texas Tech University Energy Savings Program October 2010 Update

    E-Print Network [OSTI]

    Zhuang, Yu

    Savings Electricity 49.11 48.27 Down 1.7% $ 91,300. Natural Gas 17.26 16.01 Down 7.2% $ 34,540. Steam 54, gasoline and natural gas. As a result of that order, Texas Tech University established the following goals Plan (Vehicles) In FY06, Governor Perry's Executive Order RP-49 required agencies to establish

  5. (MIRU2004)!W2004 G/7 7n ;~6u4V5wN%2hA--$rMxMQ$7$?+8J0LCV?dDj$K$h$k

    E-Print Network [OSTI]

    Tokyo, University of

    %-%c%s7k2L$N%^%C%A%s%0$r9T$C $F7WB,¡VN¿$N5sF0$r;;=P$9$kJK![8] $,$"$k!%Frueh $i$O$3$N ¡jK!$rMxMQ$7$F

  6. } {1538505 El5~ETL"9u6h6pl461 CSFb8&5fEe405 } 3388570 :k6L8)$5$$$?$^;T2Bg5WJ]255 Fs==0l@$5*5!9=Eo

    E-Print Network [OSTI]

    Tokyo, University of

    %s $r7+$jJV$7!$1 %U%l!¡%`Kh$K%9%-%c%s7k2L$N%^%C%A%s%0$r9T$C $F7WB,¡VN¿$N5sF0$r;;=P$9$kJK![8] $,$"$k

  7. JOURNAL DE PHYSIQUE IV Colloque C5, supplkment au Journal de Physique 11, Volume 5,juin 1995

    E-Print Network [OSTI]

    Boyer, Edmond

    processes have been designed for (a) the cleaning of InP substrates to remove surface native oxide deposition temperature, to supply the activation energy for both gas phase and surface reactions, and high have been introduced in the ITIIV MOCVD technology by using plasmas in remote configuration (RP) [2

  8. The Galactic Center Weather Forecast M. Moscibrodzka1

    E-Print Network [OSTI]

    Gammie, Charles F.

    The Galactic Center Weather Forecast M. Mo´scibrodzka1 , H. Shiokawa2 , C. F. Gammie2,3 , J*. The > 3M cloud will #12;­ 2 ­ interact strongly with gas near nominal pericenter at rp 300AU 8000GM/c2 transient phase while the flow circularizes-- accompanied by transient emission--it is natural to think

  9. EnergyPlusDeST DOE-2.1E Building energy modeling programs comparison

    E-Print Network [OSTI]

    ST #12; 1 IEA BESTest ASHRAE Standard 140[1] [2] 1 EnergyPlus, DeST, DOE-2, ESP, BLAST TRNSYS 1 ASHRAE RP865[1] 2ANSI/ASHRAE Standard 140 [4] 3 IEA SHC BESTest / [5] EnergyPlus [6] [7

  10. The design and analysis of a thermal mass groundwater flowmeter

    E-Print Network [OSTI]

    Weathers, Lenly Joseph

    1990-01-01T23:59:59.000Z

    in the Graetz problem is dT 24o dz RpV c (35a) or in dimensionless form: dd 4 dX Pe (356) The second snd third assumptions require modification of the numerical algorithm. Hence, the algorithm described in the previous section is used for flowmeter...

  11. Maintenance scheduling problems as benchmarks for constraint algorithms

    E-Print Network [OSTI]

    Dechter, Rina

    units within a power plant. We show how these scheduling prob­ lems can be cast as constraint average performance. For instance, a backtracking­ based algorithm that incorporates features support through grant RP 8014­06. 1 #12; often in practice have substantially better performance than

  12. BP Statistical Review of World Energy

    E-Print Network [OSTI]

    Laughlin, Robert B.

    32 Reserves 32 Prices 34 Production 35 Consumption Nuclear energy 36 Consumption Hydroelectricity 38 Consumption Primary energy 40 Consumption 41 Consumption by fuel 43 R/P ratios Appendices 44 Approximate 1965 for many sections. · Additional data for natural gas, coal, hydroelectricity, nuclear energy

  13. Assembling a viable, generic Risk-Based PV&T

    E-Print Network [OSTI]

    Das, Suman

    Based Methods, ASME PCC-3-2007. Risk-Based Inspection Technology, API RP 581, 2nd Edition, September Mitigation: Inspection Repair Replace Refer ASME PCC-3-2007, Fig. 3.3.4 #12;11/13/2014 5 The 6 step by NDE technicians, consider permanent labels, barcodes, QR codes etc. that correspond

  14. 1003.ps

    E-Print Network [OSTI]

    Nov 17, 2004 ... growth force many traffic attractors and generators to locate in places ... for using vehicles and a variable cost for the distance traveled, we arrive at the following ... costs, speed, maximum travel time, and availability. ... [31], and [32]), HV RP has received much less attention from the Operations Research.

  15. Earth Energy Resources Inc. 2010 ICSE CONFERENCE, April 28, 2010 FORWARD LOOKING STATEMENTS

    E-Print Network [OSTI]

    Utah, University of

    oil reserves were 21 billion barrels in 2006 according to the Energy Information Administration · Reserves to Production ratio (R/P) equaled 11.26 years in 2007 · Daily 2010 US oil consumptio of the "Ophus Process" technology, business strategy and strengths, capital expenditures, reserves, estimated

  16. Towards a Statistical Framework for Source Anonymity in Sensor Networks

    E-Print Network [OSTI]

    Poovendran, Radha

    , Washington Siemens Corporate Technology, M¨unchen, Germany Email: {alomair,awclark,rp3}@uw.edu, jorge.cuellar@siemens for an appropriate data transformation that removes or minimize the effect of the nuisance information. By doing so, we transform the problem from analyzing real-valued sample points to binary codes, which opens

  17. Intraspecific evolution of Canary Island Plecotine bats, based on mtDNA sequences

    E-Print Network [OSTI]

    Brown, Richard

    Intraspecific evolution of Canary Island Plecotine bats, based on mtDNA sequences J Pestano1 , RP investigated in the endemic Canary Island bat Plecotus teneriffae, based on B1 kb of mtDNA from the 16S r of differentiation between Canary Islands were quite high relative to Pipis- trelle-like bats, consistent

  18. Proceedings of the International conference on Advanced Design and Manufacture 8-10 January, 2006, Harbin, China

    E-Print Network [OSTI]

    Nan, Liangliang

    , Harbin, China MODELING FOR LASER-MATERIAL INTERACTION TO PREDICT AND CONTROL THE CROSS SECTIONALAREA OF COAXIAL LASER CLADDING WITH POWDER Liangliang Nan 1,2 , Weijun Liu 1 , Kai Zhang 1,2 1. RP Lab, Shenyang of the Chinese Academy of Sciences, Beijing 100039, China E-mail: liangliang.nan@gmail.com Abstract Laser

  19. Analytical Potential Energy Surface for the Na + HF NaF + H reaction: Application of Conventional Transition-State Theory

    E-Print Network [OSTI]

    Analytical Potential Energy Surface for the Na + HF NaF + H reaction: Application of Conventional Transition-State Theory Alessandra F. A. Vilela, Ricardo Gargano a Patr´icia R.P. Barreto b a Instituto de from calculation of the rate constant using con- ventional Transition State Theory (TST

  20. Supporting Material How Cations Change Peptide Structure

    E-Print Network [OSTI]

    clustered by a k-means clustering as provided in the MMTSB9 with a radius of 0.7 to 1 Å of the Voronoi cells. For a quantitative comparison between the calculated and experimental spectra, we employ the reliability factor RP

  1. Deligne-Beilinson cohomology and Abelian link invariants: Torsion case

    SciTech Connect (OSTI)

    Thuillier, F. [LAPTH, Universite de Savoie, Chemin de Bellevue, BP 110, F-74941 Annecy-le-Vieux Cedex (France)

    2009-12-15T23:59:59.000Z

    For the Abelian Chern-Simons field theory, we consider the quantum functional integration over the Deligne-Beilinson cohomology classes and present an explicit path-integral nonperturbative computation of the Chern-Simons link invariants in SO(3){approx_equal}RP{sup 3}, a toy example of a 3-manifold with torsion.

  2. Contra Costa Santa Clara

    E-Print Network [OSTI]

    Pico Energy Center El Centro Unit 3 (RP) Black Rock 1, 2 & 3 Geothermal Blythe 2 Comb. Cycle (E Tracy Willow Pass GWF Tracy Lodi Energy Center Lodi Energy Center Mariposa Energy Mariposa Energy. Station ON HOLD Lodi Energy Center Russell City GWF Hanford Combined Cycle Amendment Avenal Energy

  3. Physics is the source of new concepts about the nature of the universe and is a driving force for new technologies. The fundamental physics research of one generation often

    E-Print Network [OSTI]

    Linhardt, Robert J.

    , nano and silicon photonics, solid state lighting, solar energy applications. toh-Ming lu r.P. Baker for energy and electronics applications. Vincent Meunier gail and jeffrey l. Kodosky '70 Constellation energy research ·Energyharvesting,conversion and transfer ·Solid-statelighting Particle Physics

  4. Modeling of Power and Energy Transduction of Embedded Piezoelectric Wafer Active Sensors for

    E-Print Network [OSTI]

    Giurgiutiu, Victor

    Transmitter INPUT Transmitter PWAS A'A Electrical response (7-mm transmitter) ­ Active power ­ Reactive power ­ Reactive power is dominant · capacitive behavior 0 200 400 600 0 1000 2000 3000 4000 Electrical Reactive Power frequency (kHz) Power(mW) 21 ^ 2 active RP Y V 21 ^ 2 reactive IP Y V Piezoelectric transduction

  5. CHARMED MESON PRODUCTION BY e+e- ANNIHILATION

    E-Print Network [OSTI]

    Wiss, J.E.

    2010-01-01T23:59:59.000Z

    to D° momentum spectrum at Eem = 4.028 GeV e c o"Ojj~o. lI Dhe I! IiIllmeliitum specl;nml at Eem J.I..028 r,p. n+ Gi! VlO'l; of Oil,s produced at Eem = 4.02E Three-body producti~n

  6. HOST MICROBE INTERACTIONS Microorganisms Associated with Feathers of Barn Swallows

    E-Print Network [OSTI]

    Mousseau, Timothy A.

    Contaminated Areas Around Chernobyl Gábor Árpád Czirják & Anders Pape Møller & Timothy A. Mousseau & Philipp Science+Business Media, LLC 2010 Abstract The Chernobyl catastrophe provides a rare opportunity to study migratory passerine, around Chernobyl in relation to levels of ground level environmental radiation. After

  7. 140/Journal of Essential Oil Research Vol. 22, March/April 2010 Menut et al.

    E-Print Network [OSTI]

    140/Journal of Essential Oil Research Vol. 22, March/April 2010 Menut et al. lene (10.B. Verlag, Hamburg, Germany (1998). 13. R.P. Adams, Identification of Essential Oil Components by Gas.1­14.2%). The leaf oils, which were characterized by a high content of a-copaene (14.2% against 1.0% and 0

  8. MATHEMATISCHES INSTITUT DER UNIVERSIT

    E-Print Network [OSTI]

    Forster, Otto

    JkXTPz+7Yl4TOYTCYmgjRp1c+8A6qvCoVgE5rQBu PA0myo9+emOuP5ZcL8sHkVV1At8QjFQzcdTpec01ibdxY1twEDDBZnzy+tws 4Uf5

  9. MATHEMATISCHES INSTITUT DER UNIVERSITAT MUNCHEN

    E-Print Network [OSTI]

    Forster, Otto

    JkXTPz+7Yl4TOYTCYmgjRp1c+8A6qvCoVgE5rQBu PA0myo9+emOuP5ZcL8sHkVV1At8QjFQzcdTpec01ibdxY1twEDDBZnzy+tws 4Uf5

  10. "A New Rapid Tooling Technique and Its Special Binder Study," Jack Zhou and Z. He, Journal of Rapid Prototyping, Vol. 5, No. 2, pp. 82-88, 1999.

    E-Print Network [OSTI]

    Zhou, Jack

    by the various RP systems can not be applied to real production. Rapid Tooling (RT) technology is defined and efficiently so the resultant part will be representative of production material (Jacobs, 1996). Up to now be considered. Silicone Rubber Technique and Keltool In this kind of techniques (Flint and Ellis, 1994

  11. UNIVERSIT MOHAMMED V AGDAL FACULT DES SCIENCES

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Battouta B.P. 1014 RP, Rabat ­ Maroc Tel +212 (0) 537 77 18 34/35/38, Fax : +212 (0) 537 77 42 61, http, Maroc) Examinateurs : Ahmed HAMMOUCH, PES (ENSET, Rabat, Maroc) El Mustapha MOUADDIB, PES (Université de Picardie Jules Verne, Amiens, France) Rachid OULAD HAJ THAMI, PES (ENSIAS, Rabat, Maroc) Omar BOUATTANE

  12. N49: the first robust discovery of a recombining plasma in an extra galactic supernova remnant

    E-Print Network [OSTI]

    Uchida, Hiroyuki; Yamaguchi, Hiroya

    2015-01-01T23:59:59.000Z

    Recent discoveries of recombining plasmas (RPs) in supernova remnants (SNRs) have dramatically changed our understanding of SNR evolution. To date, a dozen of RP SNRs have been identified in the Galaxy. Here we present Suzaku deep observations of four SNRs in the Large Magellanic Cloud (LMC), N49, N49B, N23, and DEM L71, for accurate determination of their plasma state. Our uniform analysis reveals that only N49 is in the recombining state among them, which is the first robust discovery of a RP from an extra-galactic SNR. Given that RPs have been identified only in core-collapse SNRs, our result strongly suggests a massive star origin of this SNR. On the other hand, no clear evidence for a RP is confirmed in N23, from which detection of recombination lines and continua was previously claimed. Comparing the physical properties of the RP SNRs identified so far, we find that all of them are categorized into the "mixed-morphology" class and interacting with surrounding molecular clouds. This might be a key to sol...

  13. The Reaction Path in Chemistry: Current Approaches and Perspectives

    E-Print Network [OSTI]

    Quapp, Wolfgang

    and tunnelling with electronic structure theory (`direct dynamics'). Includes the very latest results in excited. Some contributions reveal the progress made in interface dynamics calculations based on RP potentials concept to obtain rate constants from ab initio calculations; A. D. Isaacson. Direct dynamics methods

  14. Determining Long-Term Performance of Cool Storage Systems from Short-Term Tests, Progress Report, 6-99, Revised 12-99

    E-Print Network [OSTI]

    Reddy, T. A.; Elleson, J.; Haberl, J. S.

    1999-01-01T23:59:59.000Z

    This is the Spring 1999 progress report on ASHRAE Research Project RP 1004: Determining Long-Term Performance of Cool Storage Systems from Short-Term Tests. This report presents an update concerning the work that has been accomplished since the June...

  15. 46 (2009-6) Effect of Surface Roughness on Emittance Spectra of Metal-coated Silicon Microcavity

    E-Print Network [OSTI]

    Kasagi, Nobuhide

    to the electromagnetic resonance mode. When InGaAsSb PV cell is assumed, theoretical conversion efficiency becomes 31-372 infrared heat lamp sample & sample holder vacuum chamber IR spectrometer silver-coated mirror sapphire window lock-in amplifiervacuum pumping system data logger radiation oval mirror RP TMP radiation

  16. Nuclear structure corrections in muonic deuterium Krzysztof Pachucki

    E-Print Network [OSTI]

    Pachucki, Krzysztof

    14.20.Dh The determination of electromagnetic properties of nu- clei from precise atomic spectroscopy radii for helium, lithium and beryllium atoms are not only the most accurate ones, but also the only electronic hydrogen. The 5 discrepancy in rp is the first indication that our knowledge of interactions

  17. Cell Reports Operator Sequence Alters Gene Expression

    E-Print Network [OSTI]

    Phillips, Rob

    ,8 Jeff Gelles,4,* Jane Kondev,5,* and Rob Phillips2,* 1Department of Physics 2Department of Applied: gelles@brandeis.edu (J.G.), kondev@brandeis.edu (J.K.), phillips@pboc.caltech.edu (R.P.) http

  18. Original article Prolactin release and milk removal induced

    E-Print Network [OSTI]

    Boyer, Edmond

    ewes is prevented by L-DOPA treatment RP Deis G Kann J Martinet2 1 Laboratorio de Reproducion y tétée chez la brebis allaitante. Influence sur la production du lait. L'effet de l'administration aiguë de L-DOPA sur la traite et sur la décharge de prolactine observée lors de la stimulation mam- maire

  19. An Index of the Southern Oscillation P. B. Wright

    E-Print Network [OSTI]

    Feigon, Brooke

    history and its impact on humanity; the course and causes of climate change; prospects for the future of Environmental Sciences University of East Anglia Climatic Research Unit Research Publication 4 (CRU RP4) #12 change. CRU is part of the School of Environmental Sciences at the University of East Anglia in Norwich

  20. Annually resolved patterns of summer temperature over the Northern

    E-Print Network [OSTI]

    Feigon, Brooke

    understanding in three areas: past climate history and its impact on humanity; the course and causes (published as CRU RP10 in 2012) Climatic Research Unit School of Environmental Sciences University of East with the study of natural and anthropogenic climate change. CRU is part of the School of Environmental Sciences

  1. More News (11/3) Large asteroid to pass by Earth Nov 8

    E-Print Network [OSTI]

    Walter, Frederick M.

    have been found by Doppler Wobble (radial velocity variations). This selects for massive planets close of mass) V* = 2 mp/m* /(rp)1/2 V = 2 cm/s; VJ = 3 m/s #12;Doppler Effect Emission from a moving object massive known (0.75 M) #12;Finding Extrasolar Planets. IVa Timing The Doppler Effect applied to pulse

  2. Inter-kingdom Recognition of Norepinephrine by E. Coli : Identification of the Receptors Involved in Chemotaxis

    E-Print Network [OSTI]

    Kim, Dae Nyun

    2012-10-19T23:59:59.000Z

    , AND CONCLUSIONS ....................... 28 4.1 Discussion ................................................................................... 28 4.2 Summary and conclusions ............................................................ 31 4.1... of CV1 (RP437) ........................................................... 22 3.3 Chemotactic responses to NE in the ?Plug assay ............................................. 22 3.4 Chemotactic responses of triple-knockout strain CV12...

  3. Baseline Risk Assessment for the F-Area Burning/Rubble Pits and Rubble Pit

    SciTech Connect (OSTI)

    Palmer, E. [Westinghouse Savannah River Company, AIKEN, SC (United States)

    1996-03-01T23:59:59.000Z

    This document provides an overview of the Savannah River Site (SRS) and a description of the F-Area Burning/Rubble Pits (BRPs) and Rubble Pit (RP) unit. It also describes the objectives and scope of the baseline risk assessment (BRA).

  4. Nonlinear ultimate strength analysis of fixed offshore platforms for earthquake environments

    SciTech Connect (OSTI)

    Chang, S.S. [Hudson Engineering Corp., Houston, TX (United States)

    1995-12-01T23:59:59.000Z

    The design of an offshore platform usually requires the use of ASME B31.3 and API (American Petroleum Institute) RP 2A design codes. ASME B31.3 addresses the design of pressure piping systems for offshore facilities while API RP 2A ``Recommended Practice for Planning, Designing and Constructing Fixed Offshore Platforms`` (WSD or LRFD) addresses the structural design. This paper first identifies the difference between the ASME B31.3 and API RP 2A on the earthquake load requirements. Second, the paper presents a nonlinear static pushover analysis of a typical fixed offshore platform subject to a ductility level earthquake in 394 ft (120 m) of water depth. The analysis uses a three-dimensional structural model consisting of STRUT, BEAM-COLUMN and LINEAR BEAM elements to determine the structural response while properly accounting for structure-pile-soil interaction effort. Finally, the status of current on-going efforts to implement the API RP 2A code (LRFD version) to the ISO code (International Organization for Standardization), particularly on the earthquake resistant design aspect of fixed offshore the platforms, is briefly reported.

  5. Energy Syst DOI 10.1007/s12667-009-0005-6

    E-Print Network [OSTI]

    Oren, Shmuel S.

    . Only limited control and flexibility of electric assets is currently built into electric network Currently, there is a national push for a smarter electric grid, one that is more controllable and flexible, or transmission element. R.P. O'Neill · E.A. Krall Federal Energy Regulatory Commission, Washington, DC 20426, USA

  6. IEEE TRANSACTIONS ON ROBOTICS / SHORT PAPER 1 Improving Motion Planning Algorithms by Efficient

    E-Print Network [OSTI]

    LaValle, Steven M.

    IEEE TRANSACTIONS ON ROBOTICS / SHORT PAPER 1 Improving Motion Planning Algorithms by Efficient-neighbor queries in Cartesian products of R, S1 and RP3 , the most common topological spaces in the context), which are designed for efficient nearest-neighbor generation in Rd . These techniques, however

  7. Stat 586 Interpretation of Data I (Modern Applied Statistical Modeling and Computing)

    E-Print Network [OSTI]

    Xie, Minge

    , B.D., Modern Applied Statistics with S-Plus (Springer) Cody, R.P. and Simth, J.K. Applied Statistics and the SAS Programming Language Elliott, R. J. Learning SAS in the Computer Lab (Duxbury Press). Based allows) Students should expect to use either R or SAS or Splus statistical software packages in data

  8. VOLUME 16, NUMBER 3 HVAC&R RESEARCH MAY 2010 The Effects of Filtration on

    E-Print Network [OSTI]

    Siegel, Jeffrey

    VOLUME 16, NUMBER 3 HVAC&R RESEARCH MAY 2010 273 The Effects of Filtration on Pressure Drop and Energy Consumption in Residential HVAC Systems (RP-1299) Brent Stephens Atila Novoselac, PhD Jeffrey A of high-efficiency HVAC filters is a common strategy to control exposure to airborne particulate matter

  9. This paper has been downloaded from the Building and Environmental Thermal Systems Research Group at Oklahoma State University (www.hvac.okstate.edu)

    E-Print Network [OSTI]

    Ghajar, Afshin J.

    .C. McQuiston, K. Lindsey. 1993. Development of a Revised Cooling and Heating Load Calculation Manual. #12;3637 (RP-626) DEVELOPMENTOF A REVISED COOLING AND HEATING LOAD CALCULATION MANUAL J.D. Spitler, Ph ASHRAECooling and Heating Load Calculation Manual, developed as part of ASHRAERP-626, with emphasis placed

  10. Carbon Dioxide Corrosion and Inhibition Studies

    E-Print Network [OSTI]

    Petta, Jason

    · Corrosion inhibition very important in the oil industry · Film forming inhibitors containing nitrogenCarbon Dioxide Corrosion and Inhibition Studies Kristin Gilida #12;Outline · Background = Zreal + Zim Rp 1/Corr Rate #12;Tafel · Measures corrosion rate directly · Measures iCORR from A and C

  11. MARTIN'S MAXIMUM AND TOWER FORCING SEAN COX AND MATTEO VIALE

    E-Print Network [OSTI]

    Viale, Matteo

    MARTIN'S MAXIMUM AND TOWER FORCING SEAN COX AND MATTEO VIALE Abstract. There are several examples, the Reflection Princi- ple (RP) implies that if I is a tower of ideals which concentrates on the class GIC1 of 1 [16], shows that if PFA+ or MM holds and there is an inaccessible cardinal, then there is a tower

  12. Soil colloid mobilization and metal transport Shea Buettner

    E-Print Network [OSTI]

    Arnold, Jonathan

    of the Department of Energy's Savannah River Site (SRS) near Aiken, SC in 1954, over 44,000 kg of depleted uranium of anthropogenic uranium from sediments to surface waters during episodic storm events. J. Environ. Qual. 25. Uranium in the Savannah River Site Environment WSRC-RP-92-315. WSRC. Thompson, A.; Chadwick, O.A.; Boman

  13. Mathematical Modelling of Glass Forming Processes J. A. W. M. Groot

    E-Print Network [OSTI]

    Eindhoven, Technische Universiteit

    deformations. The process can be modelled as a coupled thermodynamical/mechanical problem with corresponding] external force on plunger Fg [N] force of glass on plunger L [m] characteristic length T [K] temperature Tg ] plunger velocity cp [J kg-1 K-1 ] specific heat g [m s-2 ] gravitational acceleration p [Pa] pressure rp

  14. Interactive Roles of Gonadotropin-Releasing Hormone and RF-Amide Related Peptide 3 in Adenohypophyseal Physiology and Reporduction in the Mare

    E-Print Network [OSTI]

    Thorson, Jennifer Frances

    2013-01-28T23:59:59.000Z

    ??????????????...????..Adamantanecarbonyl-Arg-Phe-NH4 RFRP3 ?????????????..??...Arginine phenylalanine related peptide 3 RIA??????????????...??????????.?Radioimmunoassay rpPRL??????????????...?????...Recombinant porcine prolactin SAS??????????????...??????...?.Statistical analysis... .............................................. 6 2.4 GnRH control of reproductive seasonality .................................................... 8 2.5 Industry-induced problem............................................................................. 8 2.6 Methods to induce ovulation...

  15. On hyperbolicity in the renormalization of near-critical area-preserving maps

    E-Print Network [OSTI]

    the similarity transformations to a specific subgroup, we end up with the following operator R, R(P) = -1 G , -1 address the question of hyperbolicity. For technical reasons, we consider the third iterate of R0. In fact of is "universal", in the sense that a large class of cylinder-map families exhibit the same phenomenon

  16. Incorporating Single-nucleotide Polymorphisms Into the Lyman Model to Improve Prediction of Radiation Pneumonitis

    SciTech Connect (OSTI)

    Tucker, Susan L., E-mail: sltucker@mdanderson.org [Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Li Minghuan [Department of Radiation Oncology, Shandong Cancer Hospital, Jinan, Shandong (China)] [Department of Radiation Oncology, Shandong Cancer Hospital, Jinan, Shandong (China); Xu Ting; Gomez, Daniel [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Yuan Xianglin [Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan (China)] [Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan (China); Yu Jinming [Department of Radiation Oncology, Shandong Cancer Hospital, Jinan, Shandong (China)] [Department of Radiation Oncology, Shandong Cancer Hospital, Jinan, Shandong (China); Liu Zhensheng; Yin Ming; Guan Xiaoxiang; Wang Lie; Wei Qingyi [Department of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [Department of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Mohan, Radhe [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Vinogradskiy, Yevgeniy [University of Colorado School of Medicine, Aurora, Colorado (United States)] [University of Colorado School of Medicine, Aurora, Colorado (United States); Martel, Mary [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Liao Zhongxing [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States)

    2013-01-01T23:59:59.000Z

    Purpose: To determine whether single-nucleotide polymorphisms (SNPs) in genes associated with DNA repair, cell cycle, transforming growth factor-{beta}, tumor necrosis factor and receptor, folic acid metabolism, and angiogenesis can significantly improve the fit of the Lyman-Kutcher-Burman (LKB) normal-tissue complication probability (NTCP) model of radiation pneumonitis (RP) risk among patients with non-small cell lung cancer (NSCLC). Methods and Materials: Sixteen SNPs from 10 different genes (XRCC1, XRCC3, APEX1, MDM2, TGF{beta}, TNF{alpha}, TNFR, MTHFR, MTRR, and VEGF) were genotyped in 141 NSCLC patients treated with definitive radiation therapy, with or without chemotherapy. The LKB model was used to estimate the risk of severe (grade {>=}3) RP as a function of mean lung dose (MLD), with SNPs and patient smoking status incorporated into the model as dose-modifying factors. Multivariate analyses were performed by adding significant factors to the MLD model in a forward stepwise procedure, with significance assessed using the likelihood-ratio test. Bootstrap analyses were used to assess the reproducibility of results under variations in the data. Results: Five SNPs were selected for inclusion in the multivariate NTCP model based on MLD alone. SNPs associated with an increased risk of severe RP were in genes for TGF{beta}, VEGF, TNF{alpha}, XRCC1 and APEX1. With smoking status included in the multivariate model, the SNPs significantly associated with increased risk of RP were in genes for TGF{beta}, VEGF, and XRCC3. Bootstrap analyses selected a median of 4 SNPs per model fit, with the 6 genes listed above selected most often. Conclusions: This study provides evidence that SNPs can significantly improve the predictive ability of the Lyman MLD model. With a small number of SNPs, it was possible to distinguish cohorts with >50% risk vs <10% risk of RP when they were exposed to high MLDs.

  17. UNIVERSITY OF CALIFORNIA, SANTA CRUZ Santa Cruz Institute for Particle Physics (SCIPP)

    E-Print Network [OSTI]

    California at Santa Cruz, University of

    POSTDOCTORAL SCIENTIST The University of California, Santa Cruz invites applications for the position of Postdoctoral Scholar in the Santa Cruz Institute for Particle Physics, under the direction of Assistant of degenerative diseases leading to blindness (electrical retinal prosthesis). RANK & SALARY: Postdoctoral

  18. Type II Opsins: Evolutionary Origin by Internal Domain Duplication?

    E-Print Network [OSTI]

    California at Santa Barbara, University of

    Science+Business Media, LLC 2008 Abstract Opsins are a large group of proteins with seven transmembrane evolutionary origin, in which both groups of opsins evolved a seven-TM structure and light sensitivity independently. This convergence may indicate an impor- tant role for seven-TM protein structure for retinal

  19. Functional Ecology 2009, 23, 321329 doi: 10.1111/j.1365-2435.2008.01498.x 2008 The Authors. Journal compilation 2008 British Ecological Society

    E-Print Network [OSTI]

    McGraw, Kevin J.

    Functional Ecology 2009, 23, 321­329 doi: 10.1111/j.1365-2435.2008.01498.x © 2008 The Authors. Journal compilation © 2008 British Ecological Society Blackwell Publishing Ltd Seasonal, sexual, and quality related variation in retinal carotenoid accumulation in the house finch (Carpodacus mexicanus

  20. J. Math. Biol. DOI 10.1007/s00285-011-0484-7 Mathematical Biology

    E-Print Network [OSTI]

    Thomas, Peter J.

    . Using voltage sensitive dyes (Blasdel and Salama 1986) and optical imaging of intrinsic signals (Malach selectivity is absent in the response of retinal ganglion cells and individual cells in the visual thalamus, inter alia,1 orientation preferences are organized into a topographic map: nearby cells tend to encode

  1. Development/Plasticity/Repair Oculomotor Instabilities in Zebrafish Mutant belladonna

    E-Print Network [OSTI]

    Liu, Shih-Chii

    . Both OKR reversal and SO depend on vision and are contrast sensitive. We built a quantitative model optokinetic response; congenital nystagmus; oculomotor instability; achiasmatic; retinal ganglion cell axons by injecting li- pophilic tracer dyes revealed that all larvae with reversed OKR were achiasmatic (Rick et al

  2. Infrared retina

    DOE Patents [OSTI]

    Krishna, Sanjay (Albuquerque, NM); Hayat, Majeed M. (Albuquerque, NM); Tyo, J. Scott (Tucson, AZ); Jang, Woo-Yong (Albuquerque, NM)

    2011-12-06T23:59:59.000Z

    Exemplary embodiments provide an infrared (IR) retinal system and method for making and using the IR retinal system. The IR retinal system can include adaptive sensor elements, whose properties including, e.g., spectral response, signal-to-noise ratio, polarization, or amplitude can be tailored at pixel level by changing the applied bias voltage across the detector. "Color" imagery can be obtained from the IR retinal system by using a single focal plane array. The IR sensor elements can be spectrally, spatially and temporally adaptive using quantum-confined transitions in nanoscale quantum dots. The IR sensor elements can be used as building blocks of an infrared retina, similar to cones of human retina, and can be designed to work in the long-wave infrared portion of the electromagnetic spectrum ranging from about 8 .mu.m to about 12 .mu.m as well as the mid-wave portion ranging from about 3 .mu.m to about 5 .mu.m.

  3. adaptive optics reveal: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    adaptive optics reveal First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Retinal Microscotomas Revealed...

  4. Enrichment of canine gestation and lactation diets with n-3 polyunsaturated fatty acids to support neurologic development

    E-Print Network [OSTI]

    Heinemann, Kimberly Michele

    2005-11-01T23:59:59.000Z

    on the fatty acid composition of canine plasma phospholipids (PL) and milk during the gestation and lactation periods. The fatty acid composition of plasma PL and the retinal development of puppies reared on the same experimental diets as their mothers were...

  5. Summary of current research interests Much of our work includes the morphological characterisation of human

    E-Print Network [OSTI]

    Saunders, Mark

    , Bailey T, Zhang J, Knupp C, Cheetham ME, Greenwood J, Luthert PJ. Modulation of Sub-RPE deposits in vitro-related macular degeneration. Prog Ret Eye Res (2001) 20: 705-732. Chong NHV, Alexander RA, Waters L, Barnett KC in hereditary retinal degeneration. IOVS (1999) 40: 1298-1305 Bailey A, Luthert P, Dean A, Harding B, Janota I

  6. Wednesday, August 21, 2013 Biological Sciences Learning Center | Room 115

    E-Print Network [OSTI]

    Issa, Naoum

    the Correlation Mentor: Jacqueline Bernard, MD 9:20am Gabrielle Liu Retinal Nerve Fiber Layer and Macular Thinning Guided L5/S1 Placement of Labor Epidurals Does Not Improve Dermatomal Blockade in Parturients Mentor in Myelofibrosis Mentor: Olatoyosi Odenike, MD 11:30am Michael Ramirez Automated Segmentation of Sinus Mucosa

  7. Temporal integration of focus position signal during compensation for pursuit in optic flow

    E-Print Network [OSTI]

    Krekelberg, Bart

    Temporal integration of focus position signal during compensation for pursuit in optic flow Center in optic flow that specifies heading. Concurrent smooth pursuit causes distortion of the retinal flow on optic flow perception has received little attention. Here we separated the effects of velocity and gaze

  8. Ongoing eye movements constrain visual perception Ziad M Hafed & Richard J Krauzlis

    E-Print Network [OSTI]

    Krauzlis, Richard J.

    Ongoing eye movements constrain visual perception Ziad M Hafed & Richard J Krauzlis Eye movements a variety of mechanisms that compensate for the retinal consequences of eye movements. However, eye that eye movements significantly promoted perceptual coherence compared to fixation. These results indicate

  9. COLUMBIA UNIVERSITY HEALTH SCIENCES DIVISION

    E-Print Network [OSTI]

    Jia, Songtao

    that may occur are erythema (sunburn), photokeratitis (a feeling of sand in the eyes), retinal burns as if there was sand in the eyes. Photokeratitis manifests as an aversion to bright light. The severity replacement or maintenance work. Control Measures Protection against exposure may be achieved by a combination

  10. The FASEB Journal Research Communication DICER1 is essential for survival of postmitotic rod

    E-Print Network [OSTI]

    Palczewski, Krzysztof

    Sciences, Case Western Reserve University, School of Medicine, Cleveland, Ohio, USA; and § Department of parafoveal rods is a normal component of retinal aging in humans, and these same central rods are the first characterized in a variety of vertebrate experimental systems, including fly, frog, fish, and mouse (5­12). Loss

  11. The following text on page 242 of Vision and the Coding of Natural Images by B.A. Olshausen and D.J. Field, American Scientist, vol. 88 (2000) is partially obscured

    E-Print Network [OSTI]

    Olshausen, Bruno

    2000-01-01T23:59:59.000Z

    that arise in natural images­namely, the 1/f amplitude spectrum. He showed that the optimal operation a spatial-frequency power spectrum that is flat­the spatial-frequency equivalent of white noise­which is just what Atick's transformation yields. Atick's theory thus explains why retinal neurons have

  12. "Advances and Controversies" Orange County leads the world in innovative eye technology. In this two day symposium, key leading

    E-Print Network [OSTI]

    Cramer, Karina

    "Advances and Controversies" Orange County leads the world in innovative eye technology. In this two day symposium, key leading surgeons will discuss the many new technologies emerging in anterior segment, oculoplastic, and retinal surgery, innovative solutions to prevent and manage complications

  13. J. Phys. Chem. 1992, 96,737-745 737 Photochemical Hole-Burning Spectroscopy of Bovine Rhodopsin and Bacterlorhodopsln

    E-Print Network [OSTI]

    Boxer, Steven G.

    is a rapid isomerization of the retinal prosthetic group. Understanding the dynamics and structural changes their lowest energy electronic absorption bands. Hole widths were -2500 cm-' full width at half-maximum (fwhm-wavelengthdependence,vibronicfeatures, and widths of the observed holes. The calculations also yield the magnitudes of the homogeneous

  14. Perspective How Does the Brain Solve

    E-Print Network [OSTI]

    Rust, Nicole

    access to a machine that produces a robust solution, and we can investigate that machine to uncover its, computational neuroscience, computer vision, and machine learning, and the traditional boundaries between''? Conceptually, we want to know how the visual system can take each retinal image and report the identities

  15. Brief article Prior knowledge on the illumination position

    E-Print Network [OSTI]

    Mamassian, Pascal

    -retinal knowledge (Rock, 1983). Recent experimental work has emphasized the study of prior knowledge and P was upside-down and consequently shadows were in the wrong place relative to the light source. The position. This explanation rests on the knowledge that the light source stays at the same location whether or not one

  16. Evolving into epilepsy: Multiscale electrophysiological analysis and imaging in an animal model

    E-Print Network [OSTI]

    Slatton, Clint

    direct communication, control, and inter- action with the nervous system. Advances in retinal, motor detection/prediction neuroprosthetics has been faced with the search for electrophysiologic control of occurrences and duration of their bursting activity after injury to the contra-lateral hippocampus. The trends

  17. inside Stanford medicineNews from Stanford University Medical Center Volume 4, No. 10 May 21, 2012 Published by the Office of Communication & Public Affairs

    E-Print Network [OSTI]

    Bogyo, Matthew

    By Jonathan Rabinovitz Using tiny solar-panel-like cells surgically placed underneath the retina, scientists a sponsor to support tests in humans. "it works like the solar panels on your roof, converting light- cepted indicators of visual activity, from retinal cells. the scientists are now test- ing the system

  18. Optimization Principles in Neural Coding and Computation NIPS 2004 Tutorial

    E-Print Network [OSTI]

    Optimization Principles in Neural Coding and Computation NIPS 2004 Tutorial Monday, December 13 in a discussion of optimization? the classic example: photon counting in vision more examples, especially optimal there are notions of optimization ... #12;rhodopsin = organic pigment retinal covalently bound to (and enveloped by

  19. The role of PI3K in Ephrin-A1 induced cell retraction

    E-Print Network [OSTI]

    Fero, Daniel James

    2008-01-01T23:59:59.000Z

    Eng. 9 Suppl 1:S77-89. O'Leary, D.D. , and T. McLaughlin.retinal activity. Prog Brain Res. O'Leary, D.D. , and D.G.proper tissue development (O'Leary and Wilkinson, 1999) (

  20. Plasticity of opsin gene expression in cichlids from Lake Malawi

    E-Print Network [OSTI]

    Carleton, Karen L.

    Plasticity of opsin gene expression in cichlids from Lake Malawi CHRISTOPHER M. HOFMANN, KELLY E. O plasticity has important evolutionary implications. In this study, we examined retinal plasticity in five found that the magnitude of plasticity varied across species. These findings have important implications

  1. Sulfur oxidation influence on rock phosphate solubilization in soil

    E-Print Network [OSTI]

    Correa de Souza, Osni

    1985-01-01T23:59:59.000Z

    cd 7. 2 e 10. 6 c 13. 8 b 15. 1 a 8. 8 Catalgo RP Source 0 100 200 400 800 0 100 200 400 800 0 0 0 0 0 (5:1) (5:I) (5:I) (5:I) (5:I) 0. 5 b 0. 8 b 0. 8 b 0. 9 b 0. 9 b 0. 5 b 0. 9 b 1. 7 a 1. 9 a 0. 8 b 3. 6 4. 9 4. 7... 14. 7 a 9. 8 e Patos de Minas RP Source 0 100 200 400 800 0 100 200 400 800 0 0 0 0 0 (5:I) (5:I) (5:I) (5:I) (5:I) 0. 5 bc 0. 7 bc 0. 6 bc 0. 9 b 1. 0 b 0. 6 bc 1. 1 b 1. 6 a 0. 7 bc 0. 4 c 3. 7 d 4. 4 cd 4. 7 cd 5. 4...

  2. Statistics of Stationary Points of Random Finite Polynomial Potentials

    E-Print Network [OSTI]

    Mehta, Dhagash; Sun, Chuang

    2015-01-01T23:59:59.000Z

    The stationary points (SPs) of the potential energy landscapes (PELs) of multivariate random potentials (RPs) have found many applications in many areas of Physics, Chemistry and Mathematical Biology. However, there are few reliable methods available which can find all the SPs accurately. Hence, one has to rely on indirect methods such as Random Matrix theory. With a combination of the numerical polynomial homotopy continuation method and a certification method, we obtain all the certified SPs of the most general polynomial RP for each sample chosen from the Gaussian distribution with mean 0 and variance 1. While obtaining many novel results for the finite size case of the RP, we also discuss the implications of our results on mathematics of random systems and string theory landscapes.

  3. Differential stoichiometry among core ribosomal proteins

    E-Print Network [OSTI]

    Nikolai Slavov; Sefan Semrau; Edoardo Airoldi; Bogdan Budnik; Alexander van Oudenaarden

    2015-04-15T23:59:59.000Z

    Understanding the regulation and structure of ribosomes is essential to understanding protein synthesis and its deregulation in disease. While ribosomes are believed to have a fixed stoichiometry among their core ribosomal proteins (RPs), some experiments suggest a more variable composition. Testing such variability requires direct and precise quantification of RPs. We used mass-spectrometry to directly quantify RPs across monosomes and polysomes of mouse embryonic stem cells (ESC) and budding yeast. Our data show that the stoichiometry among core RPs in wild-type yeast cells and ESC depends both on the growth conditions and on the number of ribosomes bound per mRNA. Furthermore, we find that the fitness of cells with a deleted RP-gene is inversely proportional to the enrichment of the corresponding RP in polysomes. Together, our findings support the existence of ribosomes with distinct protein composition and physiological function.

  4. The Nature of Running Penumbral Waves Revealed

    E-Print Network [OSTI]

    D. Shaun Bloomfield; Andreas Lagg; Sami K. Solanki

    2007-09-24T23:59:59.000Z

    We seek to clarify the nature of running penumbral (RP) waves: are they chromospheric trans-sunspot waves or a visual pattern of upward-propagating waves? Full Stokes spectropolarimetric time series of the photospheric Si I 10827 \\AA line and the chromospheric He I 10830 \\AA multiplet were inverted using a Milne-Eddington atmosphere. Spatial pixels were paired between the outer umbral/inner penumbral photosphere and the penumbral chromosphere using inclinations retrieved by the inversion and the dual-height pairings of line-of-sight velocity time series were studied for signatures of wave propagation using a Fourier phase difference analysis. The dispersion relation for radiatively cooling acoustic waves, modified to incorporate an inclined propagation direction, fits well the observed phase differences between the pairs of photospheric and chromospheric pixels. We have thus demonstrated that RP waves are in effect low-beta slow-mode waves propagating along the magnetic field.

  5. Estimation of some characteristics of driver responses at freeway entrance ramps by probit analysis

    E-Print Network [OSTI]

    LaMotte, Lynn Roy

    1966-01-01T23:59:59.000Z

    it does or does not exhibit a given response (usually, "gets killed" ). Each . sub)ect is assumed te have a tolerance s fer the stimulus. If the stimulus is greater than . s the animal responds, if not, the animal does not respond. Associated... - 6a K wx 2 r-P Z Z w(:)x ? (6a' ? x5b) Z wx z zwx2 Z (:)(x-x) + 6 Z Z w or, (22) 6b Z w(w-x) = Z w(x-x)(:) Let y = Y + ? ; y is called the working probit. Then r-P (20) becomes (23) 6a' Z w = E w(y-Y) ZwyaEW 12 from which (24) a' + sa...

  6. Improvement of wave form of automatic watt regulator

    E-Print Network [OSTI]

    Vick, John Edward

    1957-01-01T23:59:59.000Z

    & the load output resistor of Figure 5& in con]unction w1th other circuit components in the watt regulator. This circuit may be analyzed for overall gain a' s follows: Figurc 7 Rp Eo AEo Ia PZg = Ia(Ry+RL+Rp) + laRg AEo = IiR~ + Ia(Rg+Rf) (2) PZg... = VEs 8'(i~+Is)Ry AEo ( I&RL) A (3) By substituting equation 3 in equation l and equat1on g in equation 2& the following equations may be wrItten. ' 20- pEs Z. j( ~+1)Rk+RL+Bg + Zs( 1+g)Rk 0 = Zz(Rk-ARZ, ) + Za(Rk+Bf) (5) Row the gain A may...

  7. QCRI, Qatar Foundation, Doha, QA amoschitti@qf.org.qa

    E-Print Network [OSTI]

    Moschitti, Alessandro

    energy IN in NP DT this NN form ROOT SBARQ WHADVP WRB When S VP VBN hit PP IN by NP NNS electrons , , NP DT a NN phosphor VP VBZ gives PRP RP off NP NP JJ electromagnetic NN energy PP IN in NP DT this NN form PAS A0 electrons predicate hit AM When PAS A0 a phosphor predicate give off A1 energy AM

  8. Investigation of the effect of gel residue on hydraulic fracture conductivity using dynamic fracture conductivity test

    E-Print Network [OSTI]

    Marpaung, Fivman

    2009-05-15T23:59:59.000Z

    ) ............................................................................ 51 Figure B.9: Fracture Conductivity Behavior (Polymer Concentration = 50 lb/Mgal and Gas Rate = 0.5 slm) ............................................................................ 52 Figure B.10: Fracture Conductivity Behavior (Polymer... documented in API RP-61 (1989). The recommended conditions and procedure for the test includes loading a known proppant concentration (generally 2 lb/ft2) uniformly between two steel pistons at ambient temperature, maintaining closure stress for 15 minutes...

  9. Attoyac Bayou Bacterial Source Tracking Report

    E-Print Network [OSTI]

    Martin, E.; Gentry, T.; Gregory, L.; Wagner, K.

    2014-01-01T23:59:59.000Z

    iv List Of Tables Table 1. Texas E. coli BST Library (ver. 5-13, cross-library validation) composition and rates of correct classification (RCCs) by Jackknife analysis of ERIC-RP composite data sets using an 80% similarity cutoff and three... v List of Acronyms ARCC Average Rate of Correct Classification BST Bacterial Source Tracking DNA Deoxyribonucleic Acid E. coli Escherichia coli ERIC Enterobacterial Repetitive Intergenic Consensus Sequence mTEC Modified...

  10. Proceedings: 2003 Radiation Protection Technology Conference

    SciTech Connect (OSTI)

    None

    2004-04-01T23:59:59.000Z

    Health physics professionals within the nuclear industry are continually upgrading their programs with new methods and technologies. The Third Annual EPRI Radiation Protection Technology Conference facilitated this effort by communicating technical developments, program improvements, and experience throughout the nuclear power industry. When viewed from the perspective of shorter outages, diminishing numbers of contract RP technicians and demanding emergent work, this information flow is critical for the industry.

  11. Thermal Energy Storage: It's not Just for Electric Cost Savings Anymore 

    E-Print Network [OSTI]

    Andrepont, J. S.

    2014-01-01T23:59:59.000Z

    ”, ASHRAE 1994 Annual Meeting, Seminar 03. 3. Andrepont, John S., 3rd Quarter 1995, “Chilled- Water Storage: A Suite of Benefits for District Cooling”, IDEA District Energy magazine, Volume 81, No. 1. 4. Andrepont, John S., February 2000, “Long... Meeting, Seminar 10. 14. Gansler, Robert, August 1999, “Energy and Environmental Impacts of Space Conditioning Systems”, Report on ASHRAE Research Project 991-RP, University of Wisconsin HVAC&R Center, Madison, Wisconsin. 15. Liebendorfer, Kurt M...

  12. Texas Tech University Energy Savings Program October 2009 Update

    E-Print Network [OSTI]

    Zhuang, Yu

    .08 49.11 Down 1.9% $ 117,300 Natural Gas 16.19 17.26 Up 6.6% ($ 22,700) Steam 59.47 54.88 Down 7 and natural gas. As a result of that order, Texas Tech University established the following goals related (Vehicles) In FY06, Governor Perry's Executive Order RP-49 required agencies to establish an energy

  13. Texas Tech University Energy Savings Program January 2010 Update

    E-Print Network [OSTI]

    Zhuang, Yu

    Electricity 11.99 11.69 Down 2.5% $ 26,920 Natural Gas 3.86 3.42 Down 11.4% $ 10,180 Steam 12.81 10.85 Down 15, gasoline and natural gas. As a result of Page 2 of 6 January 2010 Energy Report #12;that order, Texas Tech Plan (Vehicles) In FY06, Governor Perry's Executive Order RP-49 required agencies to establish

  14. Texas Tech University Energy Savings Program April 2010 Update

    E-Print Network [OSTI]

    Zhuang, Yu

    Electricity 24.37 23.78 Down 2.4% $ 65,170 Natural Gas 10.14 9.59 Down 5.4% $ 13,440 Steam 30.33 31.18 Up 2 consumption of electricity, gasoline and natural gas. As a result of Page 2 of 6 April 2010 Energy Report #12.4994 -0.1% 3. Fleet Fuel Management Plan (Vehicles) In FY06, Governor Perry's Executive Order RP-49

  15. Compilation of Diversity Factors and Schedules for Energy and Cooling Load Calculations, ASHRAE Research Project 1093, Phase III Draft Report, Compilation of Diversity Factors and Load Shapes

    E-Print Network [OSTI]

    Abushakra, B.; Haberl, J. S.; Claridge, D. E.; Sreshthaputra, A.

    2000-01-01T23:59:59.000Z

    and diversity factors from: ? 27 Office Buildings monitored by ESL ? 9 Office Buildings provided by LBNL (Energy-Edge Buildings). If time allows we will process 28 additional buildings provided to us by PNNL. These additional buildings were monitored under... The Final set of the RP-1093 buildings. 7 Further Data from PNNL Mr. Todd Taylor, from PNNL, provided us with 28 ELCAP office buildings data. These ELCAP buildings are in Seattle (WA), Oregon, and Idaho, and were monitored by the Bonneville Power...

  16. BABARPUB01/12 SLACPUB8854

    E-Print Network [OSTI]

    .A. Grillo, 16 M. Grothe, 16 C.A. Heusch, 16 R.P. Johnson, 16 W. Kroeger, 16 W.S. Lockman, 16 T. Pulliam, 16.G. Hitlin, 17 S. Metzler, 17 J. Oyang, 17 F.C. Porter, 17 A. Ryd, 17 A. Samuel, 17 M. Weaver, 17 S. Yang, 17.D. Sokolo#, 18 P. Bloom, 19 M.O. Dima, 19 S. Fahey, 19 W.T. Ford, 19 F. Gaede, 19 D.R. Johnson, 19 A

  17. BABARPUB01/10 SLACPUB8838

    E-Print Network [OSTI]

    .A. Heusch, 16 R.P. Johnson, 16 W. Kroeger, 16 W.S. Lockman, 16 T. Pulliam, 16 H. Sadrozinski, 16 T. Schalk, 17 F.C. Porter, 17 A. Ryd, 17 A. Samuel, 17 M. Weaver, 17 S. Yang, 17 R.Y. Zhu, 17 S. Devmal, 18 T, 19 W.T. Ford, 19 F. Gaede, 19 D.R. Johnson, 19 A.K. Michael, 19 U. Nauenberg, 19 A. Olivas, 19 H

  18. BABARPUB01/11 SLACPUB8823

    E-Print Network [OSTI]

    .A. Heusch, 16 R.P. Johnson, 16 W. Kroeger, 16 W.S. Lockman, 16 T. Pulliam, 16 H. Sadrozinski, 16 T. Schalk. Oyang, 17 F.C. Porter, 17 A. Ryd, 17 A. Samuel, 17 M. Weaver, 17 S. Yang, 17 R.Y. Zhu, 17 S. Devmal, 18. Fahey, 19 W.T. Ford, 19 F. Gaede, 19 D.R. Johnson, 19 A.K. Michael, 19 U. Nauenberg, 19 A. Olivas, 19 H

  19. BABARPUB01/01 SLACPUB8777

    E-Print Network [OSTI]

    .A. Grillo, 16 M. Grothe, 16 C.A. Heusch, 16 R.P. Johnson, 16 W. Kroeger, 16 W.S. Lockman, 16 T. Pulliam, 16.E. Hanson, 17 D.G. Hitlin, 17 S. Metzler, 17 J. Oyang, 17 F.C. Porter, 17 A. Ryd, 17 A. Samuel, 17 M. Weaver.C. van Hoek, 19 D.R. Johnson, 19 A.K. Michael, 19 U. Nauenberg, 19 A. Olivas, 19 H. Park, 19 P. Rankin

  20. BABAR-PUB-01/01 SLAC-PUB-8777

    E-Print Network [OSTI]

    ,16 A.M. Eisner,16 A. Frey,16 A.A. Grillo,16 M. Grothe,16 C.A. Heusch,16 R.P. Johnson,16 W. Kroeger,16. Samuel,17 M. Weaver,17 S. Yang,17 R.Y. Zhu,17 S. Devmal,18 T.L. Geld,18 S. Jayatilleke,18 S,19 W.C. van Hoek,19 D.R. Johnson,19 A.K. Michael,19 U. Nauenberg,19 A. Olivas,19 H. Park,19 P. Rankin

  1. ME 6222: Manufacturing Processes and Systems Prof. J.S. Colton GIT 2011

    E-Print Network [OSTI]

    Colton, Jonathan S.

    © GIT 2011 7 Forging pressure - sliding dr hp dp R rp flow r 2 2 rR h p flow r 2 exp 2 forging pressure ­ sliding drrrR hrR drr p rR p R rk R r flow r kflow ave kk 2 exp 2 2 Prof. J.S. Colton © GIT 2011 9 Average forging pressure ­ sliding

  2. Thermal Insulation Performance in the Process Industries: Facts and Fallacies

    E-Print Network [OSTI]

    Tye, R. P.

    Guarded Hot Box Study on Thermal Performance of Fibrous Insulations Used in Lofts," private com munication. 295 ESL-IE-85-05-54 Proceedings from the Seventh National Industrial Energy Technology Conference, Houston, TX, May 12-15, 1985 ...THERMAL INSULATION PERFORMANCE IN 'mE PROCESS INDUSTRIES: FACTS AND FALLACIES R.P. Tye Dynatech RID Company, Cambridge, MA, U.S.A. ABSTRACT The efficient use of thermal insulation materials and systems for design of cryogenic and elevated...

  3. 5/14/10 6:44 AMHow to Clean Up the Oil |Triple Pundit Page 1 of 3http://www.triplepundit.com/2010/05/how-to-clean-up-the-oil/

    E-Print Network [OSTI]

    Hazen, Terry

    , dumping 220,000 tons of heavy crude oil into the Atlantic. The spill was so large that the entire Brittany5/14/10 6:44 AMHow to Clean Up the Oil |Triple Pundit Page 1 of 3http://www.triplepundit.com/2010/05/how-to-clean-up-the-oil/ By RP Siegel | May 14th, 2010 View Comments How to Clean Up the Oil Like

  4. How Hungarian data protection framework is used for crime

    E-Print Network [OSTI]

    Alexin, Zoltán

    agreement, or c) when processing is provided for by a law because it is necessary for the performanceD. University of Szeged, Department of Software Engineering H-6720 Szeged Árpád tér 2. e-mail: alexin ,,Infocommunication technologies and the society of the future (FuturICT.hu)" project TÁMOP-4.2.2.C-11/1/KONV-2012

  5. The effect of postnatal exposure to ethanol and/or Monosodium-L-glutamate on plasma luteinizing hormone

    E-Print Network [OSTI]

    Wagner, Robert William

    1987-01-01T23:59:59.000Z

    for teaching me the art of RIA assays. I also sincerely appreciate the guidance and support of Dr . George G. Stott for being on my graduate committee and for his friendship, encouragement and especially the invaluable assistance in reviewing my thesis... were analyzed utilizing analysis of variance (ANOVA). The LH concentrations were determined for all samples collected utilizing NIDDK r adiolmmunoassay (RIA) kit for rats, with the RP-2 LH reference standard. The data from the LH RIA...

  6. An Experimental Study into the Ignition of Methane and Ethane Blends in a New Shock-tube Facility

    E-Print Network [OSTI]

    Aul, Christopher Joseph Erik

    2011-02-22T23:59:59.000Z

    the reflected shock wave Abbreviations BP backing pump for driven section DP driver pump for driver section GRI Gas Research Institute NTC negative temperature coefficient PT pressure transducer RCM rapid compression machine RMS root-mean square RP....................................................................................................................................98 xi LIST OF FIGURES Page Figure 1. Shock-tube diagram outlining traditional gas dynamic effects ...................... 3? Figure 2. Shock tube facility with two available configurations shown ........................ 9? Figure 3...

  7. Normalization of Process Safety Metrics 

    E-Print Network [OSTI]

    Wang, Mengtian

    2012-10-19T23:59:59.000Z

    , for this research, the number of process safety incidents is not available; since all the companies just started recording process safety incidents after API RP 745 was issued. Therefore, the most similar reported indicator-operational oil spills is used... for lagging metrics testing as a proper substitute. The major related data was obtained for this section as follows: • Process and environmental incidents (operational oil spills) • Total oil production volume • Total natural gas production volume • Total...

  8. vol. 165, no. 6 the american naturalist june 2005 Eocene Plant Diversity at Laguna del Hunco and

    E-Print Network [OSTI]

    Wilf, Peter

    ´o Pichileufu´, Patagonia, Argentina Peter Wilf,1,* Kirk R. Johnson,2, N. Rube´n Cu´neo,3, M. Elliot Smith,4´o Pichileufu´ (RP) in Patagonia, Argentina. These sites represent a frost-free humid biome in South American tuff is0.05 reanalyzed here as Ma. Thus, diverse floral associations51.91 0.22 in Patagonia evolved

  9. Convergence of a Mixed Finite Element -Finite Volume Method for the Two Phase Flow in Porous Media

    E-Print Network [OSTI]

    Ohlberger, Mario

    the following system of partial di erential equations: div u(x; t) = 0 u(x; t) = a(c; x) (rp(x;t) + (c; x)) @tc(x; t)+ div (u(x; t)c(x;t)) div ( rc(x; t)) = f(x; t); with (x; t) 2 (0; T). Here u denotes the Darcy or immiscible ow of water and oil in a reservoir the convection of the concentration is dominant to the di usion

  10. Overview of Existing Literature On Diversity Factors and Schedules for Energy and Cooling Load Calculations

    E-Print Network [OSTI]

    Abushakra, B.; Haberl, J.S.; Claridge, D.E

    used in simulation. The goal of ASHRAE 1093-RP was to compile a library of schedules and diversity factors based on measured electricity consumption data for use in energy simulations and peak cooling load calculations in office buildings... consumption data for commercial buildings. The literature on diversity factors and load shapes was examined with particular attention to the descriptions of methods used, references to existing databases of monitored whole-building energy use and end...

  11. Market analysis methodology: a utility case study. Final report

    SciTech Connect (OSTI)

    Diamond, M.

    1985-02-01T23:59:59.000Z

    The case study described in this report was conducted as part of EPRI Project RP1634 - Analytic Methods Used Outside the Electric Utility Industry. The primary objectives of the project were to: (1) explore planning and analysis techniques in use outside the utility industry, (2) identify those techniques which show promise for addressing utility issues, and (3) test them in actual utility situations to understand their real value, and the issues associated with adapting them to utility use.

  12. Neutrinoless double beta decay search with the NEMO 3 experiment

    E-Print Network [OSTI]

    Irina Nasteva; for the NEMO 3 Collaboration

    2008-10-03T23:59:59.000Z

    The NEMO 3 experiment searches for neutrinoless double beta decay and makes precision measurements of two-neutrino double beta decay in seven isotopes. The latest two-neutrino half-life results are presented, together with the limits on neutrinoless half-lives and the corresponding effective Majorana neutrino masses. Also given are the limits obtained on neutrinoless double beta decay mediated by Rp-violating SUSY, right-hand currents and different Majoron emission modes.

  13. The periodic variations of the covariance and the effect on the probability of collision

    E-Print Network [OSTI]

    Yang, Jung-Hwa

    2002-01-01T23:59:59.000Z

    variation l. (0 &p: 0 ~ 05~ G&p: l cF&0: rr) QBd o'rp: rl / 10) 2. 5 x10 4 o vs Time 15 X o 1 0. 5 x10 5 3 0 0 1 2 3 time (orbit) Figure 3. 3 Simple covariance variation 2. (rr?, =1/3, rr?, =1, cr?, = J2n, and o, =1/2) 31 The out of plane...

  14. The reactions and ashes of thermonuclear explosions on neutron stars

    E-Print Network [OSTI]

    J. L. Fisker; E. Brown; M. Liebendoerfer; F. -K. Thielemann; M. Wiescher

    2004-08-04T23:59:59.000Z

    This paper reports on the detailed rp-process reaction flow on an accreting neutron star and the resulting ashes of a type I X-ray burst. It is obtained by coupling a 298 isotope reaction network to a self-consistent one-dimensional model calculation with a constant accretion rate of dM/dt=1.0e17g/s (0.09 Eddington).

  15. 18th Annual International Conference of the IEEE Engineering in MIedicineand BiollogySociety, Amsterdam 1996 3.3.1: MR Imaging Systems and Reconstruction Techniques

    E-Print Network [OSTI]

    Ider, Yusuf Ziya

    Society, Amsterdam 1996 3.3.1: MR Imaging Systems and Reconstruction Techniques MEASURINGAC MAGNETIC FIELD is given in Fig.1. In the absence of an applied AC current, this pulse sequence is the same asthe one used by Maudsley A.A. et.al. to calculate the DC magnetic field inhomo se RP .,A_ II I f 0Gz I " v - who & - Fig.1

  16. Himalayan Journal of Sciences Volume 5, Issue 7 (Special Issue), 2008

    E-Print Network [OSTI]

    Himalayan Association for the Advancement of Science

    2008-01-01T23:59:59.000Z

    , RP Gupta and MK Arora, Page 142 Vertical stratigraphic variations and sedimentation model of the Lower Siwalik sequence in Kumaun Himalaya, India UK Shukla and DS Bora. Page 143 Amphibole compositions as indicators of deep crustal and mantle... ) | 200810 Crustal velocity structure from surface wave dispersion tomography in the Indian Himalaya Warren B Caldwell, Simon L Klemperer, Shyam S Rai and Jesse F Lawrence, Page 33 Non-coaxial heterogeneous deformation in the Num orthogneiss (Arun valley...

  17. NOx reduction through combustion optimization at PEPCO`s Potomac River Station

    SciTech Connect (OSTI)

    Cramer, D.S.; Williams, S.E.; Watkins, J.T. [Potomac Electric Power Company, Upper Marlboro, MD (United States)] [and others

    1995-06-01T23:59:59.000Z

    This paper describes the work done under EPRI Project RP 3383 at Potomac River Station to reduce NOx emissions by adjusting boiler controls. it details the method followed by PEPCO and Lehigh engineers to achieve a 35% reduction in average NOx emissions over a one-month extended test. Parameters that had the largest effect on NOx are discussed. A description of instruments installed to better monitor and control combustion is included.

  18. !#"$ %& ')(021!3")405406789"@BAC(%&D FHGPIRQ2SUT8VWT8XXYV8`#Iba5cedfY`g2T8hi`gDpqYhiV8YrpqIts

    E-Print Network [OSTI]

    Pacienza, Gianluca

    ¢txtoi£wi¢©2iǤ¾È¦ s t g i ti«¯twx)t 9o 9x%ti¯©Éi¯© £w¯«i£dxxw ËÊ imxÌi¢tiCb©rp £wti txtoi£wi9¨Íq 2oux w¯á s i£¢ w ¨ e ¨8mwi£i¢ xâ )titti£¹9wti FHw Hs q¢tt¦r$ t I i£w£)2xt £¹ix S w xxxei£ c ix

  19. Bacterial Source Tracking to Support the Development and Implementation of Watershed Protection Plans for the Lampasas and Leon Rivers: Lampasas River Watershed Final Report

    E-Print Network [OSTI]

    Gregory, L.; Casarez, E.; Truesdale, J.; Di Giovanni, G.; Owen, T.; Wolfe, J.

    2013-04-25T23:59:59.000Z

    Texas Water Resources Institute TR 441 April 2013 Bacterial Source Tracking to Support the Development and Implementation of Watershed Protection Plans for the Lampasas and Leon Rivers L. Gregory, E. Casarez, J. Truesdale, G. Di Giovanni, R... Oxygen E. coli Escherichia coli EPA Environmental Protection Agency ERIC-PCR Enterobacterial Repetitive Intergenic Consensus Sequence Polymerase Chain Reaction ERIC-RP ERIC-PCR and RiboPrinting Composite DNA Fingerprints LRW Leon River...

  20. Radiation Protection Group Annual Report 2003

    E-Print Network [OSTI]

    Silari, M

    2004-01-01T23:59:59.000Z

    The RP Annual Report summarises the activities carried out by CERN’s Radiation Protection Group in the year 2003. It includes contribution from the EN section of the TIS/IE Group on environmental monitoring. Chapter 1 reports on the measurements and estimations of the impact on the environment and public exposure due to the Organisation’s activities. Chapter 2 provides the results of the monitoring of CERN’s staff, users and contractors to occupational exposure. Chapter 3 deals with operational radiation protection around the accelerators and in the experimental areas. Chapter 4 reports on RP design studies for the LHC and CNGS projects. Chapter 5 addresses the various services provided by the RP Group to other Groups and Divisions at CERN, which include managing radioactive waste, high-level dosimetry, lending radioactive test sources and shipping radioactive materials. Chapter 6 describes activities other than the routine and service tasks, i.e. development work in the field of instrumentation and res...

  1. Asymmetric crystallization during cooling and heating in model glass-forming systems

    E-Print Network [OSTI]

    Minglei Wang; Kai Zhang; Zhusong Li; Yanhui Liu; Jan Schroers; Mark D. Shattuck; Corey S. O'Hern

    2015-01-09T23:59:59.000Z

    We perform molecular dynamics (MD) simulations of the crystallization process in binary Lennard-Jones systems during heating and cooling to investigate atomic-scale crystallization kinetics in glass-forming materials. For the cooling protocol, we prepared equilibrated liquids above the liquidus temperature $T_l$ and cooled each sample to zero temperature at rate $R_c$. For the heating protocol, we first cooled equilibrated liquids to zero temperature at rate $R_p$ and then heated the samples to temperature $T > T_l$ at rate $R_h$. We measured the critical heating and cooling rates $R_h^*$ and $R_c^*$, below which the systems begin to form a substantial fraction of crystalline clusters during the heating and cooling protocols. We show that $R_h^* > R_c^*$, and that the asymmetry ratio $R_h^*/R_c^*$ includes an intrinsic contribution that increases with the glass-forming ability (GFA) of the system and a preparation-rate dependent contribution that increases strongly as $R_p \\rightarrow R_c^*$ from above. We also show that the predictions from classical nucleation theory (CNT) can qualitatively describe the dependence of the asymmetry ratio on the GFA and preparation rate $R_p$ from the MD simulations and results for the asymmetry ratio measured in Zr- and Au-based bulk metallic glasses (BMG). This work emphasizes the need for and benefits of an improved understanding of crystallization processes in BMGs and other glass-forming systems.

  2. Recovery of Navy distillate fuel from reclaimed product. Volume II. Literature review

    SciTech Connect (OSTI)

    Brinkman, D.W.; Whisman, M.L.

    1984-11-01T23:59:59.000Z

    In an effort to assist the Navy to better utilize its waste hydrocarbons, NIPER, with support from the US Department of Energy, is conducting research designed to ultimately develop a practical technique for converting Reclaimed Product (RP) into specification Naval Distillate Fuel (F-76). This first phase of the project was focused on reviewing the literature and available information from equipment manufacturers. The literature survey has been carefully culled for methodology applicable to the conversion of RP into diesel fuel suitable for Navy use. Based upon the results of this study, a second phase has been developed and outlined in which experiments will be performed to determine the most practical recycling technologies. It is realized that the final selection of one particular technology may be site-specific due to vast differences in RP volume and available facilities. A final phase, if funded, would involve full-scale testing of one of the recommended techniques at a refueling depot. The Phase I investigations are published in two volumes. Volume 1, Technical Discussion, includes the narrative and Appendices I and II. Appendix III, a detailed Literature Review, includes both a narrative portion and an annotated bibliography containing about 800 references and abstracts. This appendix, because of its volume, has been published separately as Volume 2.

  3. Application of organosilicon pre-sic polymer technology to optimize rapid prototyping of ceramic components

    SciTech Connect (OSTI)

    Saha, C.K.; Zank, G. [Dow Corning Corporation, Midland, MI (United States); Ghosh, A. [Philips Display Components Co., Ann Arbor, MI (United States)

    1995-12-01T23:59:59.000Z

    Developments of applications of advanced ceramics e.g., SiC, Si{sub 3}N{sub 4}, CMCs need to be on a faster track than what the current processing technologies can afford. Rapid reduction in time to market of new and complex products can be achieved by using Rapid Prototyping and Manufacturing Technologies (RP&M) e.g., 3D-printing, selective laser sintering, stereolithography etc. These technologies will help advanced ceramics meet the performance challenges at an affordable price with reliable manufacturing technologies. The key variables of the RP&M technologies for ceramics are the nature of the polymer carrier and/or the binder, and the powder. Selection and/or the production of a proper class of polymer carrier/binder, understanding their impact on the processing of ceramics such as polymer-powder interaction, speed of hardening the green body in a controlled manner, ability to retain shape during forming and consolidation, delivering desirable properties at the end, are crucial to develop the low cost, high quality ceramic products. Organosilicon pre-SiC polymer technology route to advanced ceramics is currently being commercialized by Dow Corning. Methods to use this class of polymer as a processing aid in developing potentially better RP&M technologies to make better ceramics have been proposed in this work.

  4. Direct Analysis of Reversed-Phase HPTLC Separated Tryptic Protein Digests using a Liquid Microjunction Surface Sampling Probe/ESI-MS System

    SciTech Connect (OSTI)

    Emory, Joshua F [ORNL; Walworth, Matthew J [ORNL; Van Berkel, Gary J [ORNL; Schulz, Michael [Merck Research Laboratories; Minarik, susanne [Merck Research Laboratories

    2010-01-01T23:59:59.000Z

    The sampling, ionization and detection of tryptic peptides separated in one-dimension on reversed phase HPTLC plates was performed using liquid microjunction surface sampling probe electrospray ionization mass spectrometry. Tryptic digests of five proteins (cytochrome c., myoglobin, beta-casein, lysozyme, and bovine serum albumin) were spotted on reversed phase HPTLC RP-8 F254s and HPTLC RP-18 F254s plates. The plates were then developed using 70/30 methanol/water with 0.1 M ammonium acetate. A dual purpose extraction/electrospray solution containing 70/30/0.1 water/methanol/formic acid was infused through the sampling probe during analysis of the developed lanes. Both full scan mass spectra and data dependent tandem mass spectra were acquired for each development lane to detect and verify the peptide distributions. Data dependent tandem mass spectra provided both protein identification and sequence coverage information. Highest sequence coverages were achieved for cytochrome c. and myoglobin (62.5% and 58.3%, respectively) on reversed phase RP-8 plates. While the tryptic peptides were separated enough for identification, the peptide bands did show some overlap with most peptides located in the lower half of the development lane. Proteins whose peptides were more separated gave higher sequence coverage. Larger proteins such as beta-casein and BSA which were spotted in lower relative amounts gave much lower sequence coverage than the smaller proteins.

  5. Recovery of Navy distillate fuel from reclaimed product. Volume I. Technical discussion

    SciTech Connect (OSTI)

    Brinkman, D.W.; Whisman, M.L.

    1984-11-01T23:59:59.000Z

    In an effort to assist the Navy to better utilize its waste hydrocarbons, NIPER, with support from the US Department of Energy, is conducting research designed to ultimately develop a practical technique for converting Reclaimed Product (RP) into specification Naval Distillate Fuel (F-76). The first phase of the project was focused on reviewing the literature and available information from equipment manufacturers. The literature survey has been carefully culled for methodology applicable to the conversion of RP into diesel fuel suitable for Navy use. Based upon the results of this study, a second phase has been developed and outlined in which experiments will be performed to determine the most practical recycling technologies. It is realized that the final selection of one particular technology may be site-specific due to vast differences in RP volume and available facilities. A final phase, if funded, would involve full-scale testing of one of the recommended techniques at a refueling depot. The Phase I investigations are published in two volumes. Volume 1, Technical Discussion, includes the narrative and Appendices I and II. Appendix III, a detailed Literature Review, includes both a narrative portion and an annotated bibliography containing about 800 referenvces and abstracts. This appendix, because of its volume, has been published separately as Volume 2. 18 figures, 4 tables.

  6. A Reaction Plane Detector for PHENIX at RHIC

    E-Print Network [OSTI]

    E. Richardson; Y. Akiba; N. Anderson; A. A. Bickley; T. Chujo; B. A. Cole; S. Esumi; J. S. Haggerty; J. Hanks; T. K. Hemmick; M. Hutchison; Y. Ikeda; M. Inaba; J. Jia; D. Lynch; Y. Miake; A. C. Mignerey; T. Niida; E. O'Brien; R. Pak; M. Shimomura; P. W. Stankus; T. Todoroki; K. Watanabe; R. Wei; W. Xie; W. A. Zajc; C. Zhang

    2011-03-11T23:59:59.000Z

    A plastic scintillator paddle detector with embedded fiber light guides and photomultiplier tube readout, referred to as the Reaction Plane Detector (RXNP), was designed and installed in the PHENIX experiment prior to the 2007 run of the Relativistic Heavy Ion Collider (RHIC). The RXNP's design is optimized to accurately measure the reaction plane (RP) angle of heavy-ion collisions, where, for mid-central $\\sqrt{s_{NN}}$ = 200 GeV Au+Au collisions, it achieved a $2^{nd}$ harmonic RP resolution of $\\sim$0.75, which is a factor of $\\sim$2 greater than PHENIX's previous capabilities. This improvement was accomplished by locating the RXNP in the central region of the PHENIX experiment, where, due to its large coverage in pseudorapidity ($1.0<|\\eta|<2.8$) and $\\phi$ (2$\\pi$), it is exposed to the high particle multiplicities needed for an accurate RP measurement. To enhance the observed signal, a 2-cm Pb converter is located between the nominal collision region and the scintillator paddles, allowing neutral particles produced in the heavy-ion collisions to contribute to the signal through conversion electrons. This paper discusses the design, operation and performance of the RXNP during the 2007 RHIC run.

  7. Models of Receptive Field Dynamics in Visual Cortex

    E-Print Network [OSTI]

    1999-01-01T23:59:59.000Z

    The position, size, and shape of the receptive field (RF) of some cortical neurons change dynamically, in response to artificial scotoma conditioning (Pettet & Gilbert, 1992) and to retinal lesions (Chino et al., 1992; Darian-Smith & Gilbert, 1995) in adult animals. The RF dynamics are of interest because they show how visual systems may adaptively overcome damage (from lesions, scotomas, or other failures), may enhance processing efficiency by altering RF coverage in response to visual demand, and may perform perceptual learning. This paper presents an afferent excitatory synaptic plasticity rule and a lateral inhibitory synaptic plasticity rule -- the EXIN rules (Marshall, 1995a) -- to model persistent RF changes after artificial scotoma conditioning and retinal lesions. The EXIN model is compared to the LISSOM model (Sirosh et al., 1996) and to a neuronal adaptation model (Xing & Gerstein, 1994). The rules within each model are isolated and are analyzed independently, to elucidate t...

  8. Neodymium-YAG laser vitreolysis in sickle cell retinopathy

    SciTech Connect (OSTI)

    Hrisomalos, N.F.; Jampol, L.M.; Moriarty, B.J.; Serjeant, G.; Acheson, R.; Goldberg, M.F.

    1987-08-01T23:59:59.000Z

    Six patients with proliferative sickle cell retinopathy and vitreous bands were treated with the neodymium-YAG (Nd-YAG) laser to accomplish lysis of avascular traction bands or to clear the media in front of the macula. Transection of bands was possible in five of the six cases but in two of these the effect was only partial. Three cases were satisfactorily treated with the Nd-YAG laser application alone, two eventually required conventional vitreoretinal surgery, and one patient's condition stabilized despite failure of the treatment. Complications from the treatment occurred in three cases and included subretinal (choroidal) hemorrhage, preretinal hemorrhage, microperforation of a retinal vein, and focal areas of damage to the retinal pigment epithelium. Neodymium-YAG vitreolysis may be a useful modality in carefully selected patients with proliferative sickle cell retinopathy, but potentially sight-threatening complications may occur.

  9. Exclusive Multipotency and Preferential Asymmetric Divisions in Post-Embryonic Neural Stem Cells of the Fish Retina

    E-Print Network [OSTI]

    Centanin, Lázaro; Ander, Janina -J.; Hoeckendorf, Burkhard; Lust, Katharina; Kellner, Tanja; Kraemer, Isabel; Urbany, Cedric; Hasel, Eva; Harris, William A.; Simons, Benjamin D.; Wittbrodt, Joachim

    2014-08-19T23:59:59.000Z

    . The mandatory clonality of retinal columns raises the question of its functional implications. Remarkably, two publications have recently reported that columns of neurons in the mammalian cortex have a clonal origin that favors interconnection between siblings... . This is in agreement with the absolute penetrance of RSC multipotency: RSCs do not choose between different options but rather do the very same thing irrespective of environmental conditions. Plastic responses to injuries rely on the progenitors rather than on stem...

  10. Effect of induction chemotherapy on estimated risk of radiation pneumonitis in bulky non–small cell lung cancer

    SciTech Connect (OSTI)

    Amin, Neha P., E-mail: npamin@gmail.com [Department of Radiation Oncology, Wayne State University and Karmanos Cancer Center, Detroit, MI (United States); Miften, Moyed; Thornton, Dale; Ryan, Nicole; Kavanagh, Brian; Gaspar, Laurie E [Department of Radiation Oncology, University of Colorado, Aurora, CO (United States)

    2013-10-01T23:59:59.000Z

    Patients with bulky non–small cell lung cancer (NSCLC) may be at a high risk for radiation pneumonitis (RP) if treated with up-front concurrent chemoradiation. There is limited information about the effect of induction chemotherapy on the volume of normal lung subsequently irradiated. This study aims to estimate the reduction in risk of RP in patients with NSCLC after receiving induction chemotherapy. Between 2004 and 2009, 25 patients with Stage IV NSCLC were treated with chemotherapy alone (no surgery or radiation therapy [RT]) and had computed tomography (CT) scans before and after 2 cycles of chemotherapy. Simulated RT plans were created for the prechemotherapy and postchemotherapy scans so as to deliver 60 Gy to the thoracic disease in patients who had either a >20% volumetric increase or decrease in gross tumor volume (GTV) from chemotherapy. The prechemotherapy and postchemotherapy scans were analyzed to compare the percentage of lung volume receiving?20 Gy (V20), mean lung dose (MLD), and normal tissue complication probability (NTCP). Eight patients (32%) had a GTV reduction >20%, 2 (8%) had GTV increase >20%, and 15 (60%) had stable GTV. In the 8 responders, there was an absolute median GTV decrease of 88.1 cc (7.3 to 351.6 cc) or a 48% (20% to 62%) relative reduction in tumor burden. One had >20% tumor progression during chemotherapy, yet had an improvement in dosimetric parameters postchemotherapy. Among these 9 patients, the median decrease in V20, MLD, and NTCP was 2.6% (p<0.01), 2.1 Gy (p<0.01), and 5.6% (p<0.01), respectively. Less than one-third of patients with NSCLC obtain >20% volumetric tumor reduction from chemotherapy alone. Even with that amount of volumetric reduction, the 5% reduced risk of RP was only modest and did not convert previously ineligible patients to safely receive definitive thoracic RT.

  11. Aeroelastic Modeling of Offshore Turbines and Support Structures in Hurricane-Prone Regions (Poster)

    SciTech Connect (OSTI)

    Damiani, R.

    2014-03-01T23:59:59.000Z

    US offshore wind turbines (OWTs) will likely have to contend with hurricanes and the associated loading conditions. Current industry standards do not account for these design load cases (DLCs), thus a new approach is required to guarantee that the OWTs achieve an appropriate level of reliability. In this study, a sequentially coupled aero-hydro-servo-elastic modeling technique was used to address two design approaches: 1.) The ABS (American Bureau of Shipping) approach; and 2.) The Hazard Curve or API (American Petroleum Institute) approach. The former employs IEC partial load factors (PSFs) and 100-yr return-period (RP) metocean events. The latter allows setting PSFs and RP to a prescribed level of system reliability. The 500-yr RP robustness check (appearing in [2] and [3] upcoming editions) is a good indicator of the target reliability for L2 structures. CAE tools such as NREL's FAST and Bentley's' SACS (offshore analysis and design software) can be efficiently coupled to simulate system loads under hurricane DLCs. For this task, we augmented the latest FAST version (v. 8) to include tower aerodynamic drag that cannot be ignored in hurricane DLCs. In this project, a 6 MW turbine was simulated on a typical 4-legged jacket for a mid-Atlantic site. FAST-calculated tower base loads were fed to SACS at the interface level (transition piece); SACS added hydrodynamic and wind loads on the exposed substructure, and calculated mudline overturning moments, and member and joint utilization. Results show that CAE tools can be effectively used to compare design approaches for the design of OWTs in hurricane regions and to achieve a well-balanced design, where reliability levels and costs are optimized.

  12. Are mirror planets opaque?

    E-Print Network [OSTI]

    R. Foot

    2001-05-11T23:59:59.000Z

    Over the last few years, many close orbiting ($\\sim 0.05$ A.U.) large mass planets ($\\sim M_{J}$) of nearby stars have been discovered. Their existence has been inferred from tiny Doppler shifts in the light from the star and in one case a transit has been observed. Because ordinary planets are not expected to be able to form this close to ordinary stars due to the high temperatures, it has been speculated that the close-in large planets are in fact exotic heavenly bodies made of mirror matter. We show that the accretion of ordinary matter onto the mirror planet (from e.g.the solar wind from the host star) should make the mirror planet opaque to ordinary radiation with an effective radius ($R_p$) large enough to explain the measured size of the transiting close-in extrasolar planet, HD209458b. Furthermore we obtain the rough prediction that $R_{p} \\propto \\sqrt{{T_s\\over M_p}}$ (where $T_s$, is the surface temperature of the ordinary matter in the mirror planet and $M_p$ is the mass of the mirror planet) which will be tested in the near future as more transiting planets are found. We also show that the mirror world interpretation of the close-in extra solar planets explains the low albedo of $\\tau$ Boo b because the large estimated mass of $\\tau$ Boo b ($\\sim 7M_J$) implies a small effective radius of $R_p \\approx 0.5R_J$ for $\\tau$ Boo.

  13. The vibrational and rotational structure of the 2400 to 1950 A? absorption spectrum of sulfur dioxide

    E-Print Network [OSTI]

    Riggs, James Willborn

    1958-01-01T23:59:59.000Z

    -l ap pi ng Or de rs 26 Ex te rn al Op ti cs As so ci at ed wi th Ab so rp ti on Tu be 27 28 Sulfur Dioxide Gas System.-The sulfur dioxide gas system associated with the absorption tube is pictured in Figure 3... fulfillment of' %hm r*tuir??Mi*s f?r %ift ??' m m m m m m & m s t Major Sttfejoott Rupeio* THE VIBRATIONAL AND ROTATIONAL STRUCTURE OP THE 2400 TO 1950 A ABSORPTION SPECTRUM OP SULFUR DIOXIDE A Dissertation 37 James Willborn Riggs, Jr. Approved...

  14. Determining the Fate of Herbicides in the Ogallala Aquifer.

    E-Print Network [OSTI]

    Schneider, A. D.; Wiese, A. F.; Jones, O. R.; Mathers, A. C.

    1971-01-01T23:59:59.000Z

    Aquifer A. D. SCHNEIDER, A. F. WIESE, 0. R. JONES AND A. C. M.~THERS* 11 , I jvi~i\\ \\~!~llI~llR~ ARE RECHARGED by nat~~ral or arti- ,, , iiti;~l jlrocesses, they may receive runoff from [I. , :iillltar;~l lands. In the Texas High Plains, dual- [, rp..., if needed. Nitrate and nitrite were cleterminetl by tl,c ,i~ mated, colormetric procedures of Kamphake, H.II~I~ - and Cohen (5). Herbicides in the water samples were dete~~ll~~ with a Barber-Coleman Moclel 5360 gas chromatoy equipped with a radium 226...

  15. Methodology for Analyzing Energy and Demand Savings From Energy Services Performance Contract Using Short-Term Data 

    E-Print Network [OSTI]

    Liu, Z.; Haberl, J. S.; Cho, S.; Lynn, B.; Cook, M.

    2006-01-01T23:59:59.000Z

    . REFERENCES Abushakra, B., Sreshthaputra, A., Haberl, J.S., Claridge, D.E. 2001. “Compilation of Diversity Factors and Schedules for Energy and Cooling Load Calculations”, ASHRAE Research Project 1093-RP final report, Energy Systems Laboratory Report... in Hot and Humid Climates, Orlando, Florida, July 24-26, 2006 91002_Headquarters Building Whole-Building Ele ctricity_Weekends 91002_Headquarters Building Whole-Building EI ectricity_Weekdays Buil eng 10090807040 50 60 Tdb [oF] 302010 11 A-e Retroft Data...

  16. The reactive metabolite target protein database (TPDB) – a web-accessible resource

    E-Print Network [OSTI]

    Hanzlik, Robert P.; Koen, Yakov M.; Theertham, Bhargav; Dong, Yinghua; Fang, Jianwen

    2007-03-16T23:59:59.000Z

    of Organic Functional Groups. Current Drug Metabolism 2005, 6:161-225. 9. Bambal RB, Hanzlik RP: Bromobenzene-3,4-Oxide Alkylates Histidine and Lysine Side Chains of Rat Liver Proteins in Vivo. Chem Res Toxicol 1995, 8:729-735. 10. Nerland DE, Cai J, Pierce... they are electrophilic in nature. For example, epoxides, qui- nones and Michael acceptors generally react with cysteine sulfhydryl groups but also react with lysine, histidine and, to a lesser extent, methionine or even carboxylic acid side chains in proteins [9...

  17. The Power of the Claw

    E-Print Network [OSTI]

    Rothschild, Bruce M.; Bryant, Bill; Hubbard, Christopher; Tuxhorn, Kent; Kilgore, Ginny Penn; Martin, Larry D.; Naples, Virginia L.

    2013-09-04T23:59:59.000Z

    was achieved. PLOS ONE | www.plosone.org 1 September 2013 | Volume 8 | Issue 9 | e73811 Materials and Methods All animal work was conducted according to relevant national and international guidelines, as part of an animal enrichment program, as was approved.... G v os 41: 123–131. 18. Gignac PM, Makovicky PJ, Erickson GM, Walsh RP (2010) A description of Deinonychus antirrhopus bite marks and estimates of bit force using tooth indention simulations. J Vert Paleontol 30: 1169–1177. 19. Dominato VH, Mothe´ D...

  18. Robotics and Energy Usage

    E-Print Network [OSTI]

    Hershey, R. L.; Fenton, S. E.; Letzt, A. M.

    1983-01-01T23:59:59.000Z

    , robots will play an increasing role in the coming years. Science Management Corporation has been assisting the Electric Power Research Institute (EPRI) and the manufacturers in assessing the effects of robots and re lated technologies. For EPRI... Milacron 1,000 Copperweld 735 DeVilbiss 137 Asea 85 Advanced Robotics 48 Thermwood 24 Nordson 30 Cybotech 28 Reis 3 Others 210 TOTAL 6,000 SOURCE: SMC Robotics Survey, EPRI RP1967-4, 1982 Table 2 U.S. Robot Use Classified By Applicat ion...

  19. Marketing Cool Storage Technology

    E-Print Network [OSTI]

    McCannon, L.

    ~nized for a means to provide for technology transfer and dissemination of current information in the field. The International Thermal Stora~e Advisorv Council was formed to help meet this perceived need. This paper will review activities of EPRI... of cool stora~e. At the same time, +n educational effort was needed to infotm en~ineers and end-users on the use of t~e technol02V. and of the ener~v cost savin~s th t could result. The EPRI "Commercialization of Cool Stora e Technolo~v" project (RP...

  20. BABAR-PUB-01/11 SLAC-PUB-8823

    E-Print Network [OSTI]

    A.M. Eisner,16 A. Frey,16 A.A. Grillo,16 M. Grothe,16 C.A. Heusch,16 R.P. Johnson,16 W. Kroeger,16 W,17 D. G. Hitlin,17 S. Metzler,17 J. Oyang,17 F.C. Porter,17 A. Ryd,17 A. Samuel,17 M. Weaver,17 S.D. Sokoloff,18 P. Bloom,19 S. Fahey,19 W.T. Ford,19 F. Gaede,19 D.R. Johnson,19 A.K. Michael,19 U. Nauenberg

  1. BABAR-PUB-01/10 SLAC-PUB-8838

    E-Print Network [OSTI]

    A.M. Eisner,16 A. Frey,16 A.A. Grillo,16 M. Grothe,16 C.A. Heusch,16 R.P. Johnson,16 W. Kroeger,16 W. Dvoretskii,17 D.G. Hitlin,17 S. Metzler,17 J. Oyang,17 F.C. Porter,17 A. Ryd,17 A. Samuel,17 M. Weaver,17 S.D. Sokoloff,18 P. Bloom,19 S. Fahey,19 W.T. Ford,19 F. Gaede,19 D.R. Johnson,19 A.K. Michael,19 U. Nauenberg

  2. Aircraft control using nonlinear dynamic inversion in conjunction with adaptive robust control

    E-Print Network [OSTI]

    Fisher, James Robert

    2005-02-17T23:59:59.000Z

    on the scheduling parameters [1, 2]. Dynamic Inversion may also be used to schedule control actions. The dynamics of an aircraft can be represented by the following dynamic differential equation: ? = f (x;t;G)+g(x;t;G)u x 2 Rn?1; u 2 Rp?1; (p > n) (II.1) The vector... x represents aircraft states and u represents a vector of control inputs. Only the case where p > n will be considered, although many aircraft have p = n or even p < n. The vector G consists of measurements including flight condition and states which...

  3. Stability analysis of buried flexible pipes: a biaxial buckling equation

    E-Print Network [OSTI]

    Chau, Melissa Tuyet-Mai

    1990-01-01T23:59:59.000Z

    loading are (see Appendix B for derivations) 29 rN. . +Ne~e+rp, = 0 rNes, e + Ne, a+ rpa = 0 r M*, *, +?M*a, *e + Me, ee +?e ? (?*P*, * +?N*eP*, e + - NaPe, e) 2 +r p. Ps+r pePa+r p. = o 2 2 2 (27) Introduction of Eqs. (20) and (25) into Eqs. (27...STABILITY ANALYSIS OF BURIED FLEXIBLE PIPES: A BIAXIAL BUCKLING EQUATION A Thesis by MELISSA TUYET-MAI CHAU Submitted to the Office of Graduate Studies of Texas AkM University in partial fulfillment of the requirements for the degree...

  4. Determining the size of the proton

    E-Print Network [OSTI]

    N. G. Kelkar; F. Garcia Daza; M. Nowakowski

    2012-08-02T23:59:59.000Z

    A measurement of the Lamb shift of 49,881.88(76) GHz in muonic hydrogen in conjunction with theoretical estimates of the proton structure effects was recently used to deduce an accurate but rather small radius of the proton. Such an important shift in the understanding of fundamental values needs reconfirmation. Using a different approach with electromagnetic form factors of the proton, we obtain a new expression for the transition energy, $\\Delta = E_{2P_{{3}/{2}}}^{f=2} - E_{2S_{{1}/{2}}}^{f=1}$, in muonic hydrogen and deduce a proton radius, $r_p = 0.831$ fm.

  5. Implications of various dispersants on biofilm clean up processes

    SciTech Connect (OSTI)

    Beardwood, E.S.; Therrien, J.K.

    1999-07-01T23:59:59.000Z

    A microbiologically fouled industrial cooling water system was investigated utilizing a portable corrosion and fouling monitor according to the NACE RP0189-951 Standard. Baseline data was established and at which time the monitor was subjected to various dispersants (3) typically used for organic and microbiological deposit removal. The results of this in-field, side stream, experiment on a dynamic system will be presented. A number of key points and factors influencing the performance of the foulant clean up will also be discussed.

  6. Measuring Frac-pack Conductivity at Reservoir Temperature and High Closure Stress 

    E-Print Network [OSTI]

    Fernandes, Preston X.

    2010-10-12T23:59:59.000Z

    quality and test conditions (Palisch et al. 2007). In 2007, this standard for long-term testing came to be known as the ISO 13503-5 (Kaufman et al. 2007). Seccombe and Anderson (1982) and Reinicke et al. (1985) showed through post-frac analysis... apparatus consists of the following (Fig 2.1): ? A mixing tank - to prepare the cross-linked fluid ? High pressure centrifugal pump ? Heating jacket - to increase the temperature to reservoir conditions ? Modified API RP-61 fracture conductivity cell...

  7. Improved bounds on SUSY accompanied neutrinoless double beta decay

    E-Print Network [OSTI]

    H. Päs; M. Hirsch; H. V. Klapdor-Kleingrothaus

    1999-07-14T23:59:59.000Z

    Neutrinoless double beta decay induced by light Majorana neutrino exchange between two decaying nucleons with squark/slepton exchange inside one and W exchange inside the other nucleon (so-called vector-scalar exchange) gives stringent limits on R-parity violating interactions. We have extended previous work by including the tensor contribution to the transition rate. We discuss the improved limits on trilinear \\Rp -MSSM couplings imposed by the current experimental limit on the $\\znbb$ decay half-life of $^{76}$Ge.

  8. Evaluation of electrophysiological signals as an indicator of intracranial pressure in animals with simulated hematomas 

    E-Print Network [OSTI]

    Abdul-Hay, Roger Emile

    1992-01-01T23:59:59.000Z

    human AEP waveform and the Jewett numbering system. . . . . . . . . . . . . . . 12 6. Four classes of Fourier transforms. . 18 7. An SFG of the first stage of a decimation-in-time N=2s-point FFT. . . . . . . . . . . . . . 20 8. Sample power spectrum... transform. In particular, the DFT defines a frequency domain spectrum of a time series. Continuous in time Discrete in (ime Periodic in Frequency F(r I w i pl g tf h E 5 g n 0 f(r) = ? f Fom) cion dm /' 2. J F(/rp) = f f(r)e im'd/ 0 /(k l...

  9. Validation of Bayesian posterior distributions using a multidimensional Kolmogorov-Smirnov test

    E-Print Network [OSTI]

    Harrison, Diana; Sutton, David; Carvalho, Pedro; Hobson, Michael

    2015-06-10T23:59:59.000Z

    in the presence of edge effects, the quantities Ji = [1 ? G(di)]/[1 ? F (si)] have the CDF P (J) = J/2 if 0 1. Thus, for the ith data point, one may replace the expression (7) by ?(xi) = ? f(u)>f(xi) f(u) dnu+ f?V (R)P (Ji), (8) which... between the two exam- ple distributions f(x, y) and g(x, y) mentioned above. In practice, the above approach serves to distinguish between the original PDF f(x) and any ‘reasonable’ alternative PDF that one might expect to occur in realistic scenarios...

  10. Workshop on the origin of the heavy elements: Astrophysical models and experimental challenges, Santa Fe, New Mexico, September 3-4, 1999

    SciTech Connect (OSTI)

    Robert C. Haight; John L. Ullmann; Daniel D. Strottman; Paul E. Koehler; Franz Kaeppeler

    2000-01-01T23:59:59.000Z

    This Workshop was held on September 3--4, 1999, following the 10th International Symposium on Capture Gamma-Ray Spectroscopy. Presentations were made by 14 speakers, 6 from the US and 8 from other countries on topics relevant to s-, r- and rp-process nucleosynthesis. Laboratory experiments, both present and planned, and astrophysical observations were represented as were astrophysical models. Approximately 50 scientists participated in this Workshop. These Proceedings consist of copies of vu-graphs presented at the Workshop. For further information, the interested readers are referred to the authors.

  11. Range versus confinement rearing of pullets of five egg strains and crosses on all-mash and mash and oats diets

    E-Print Network [OSTI]

    Taylor, Jimmy Neal

    1958-01-01T23:59:59.000Z

    LRtS Conf inepeut Naah 0 Differ Average Sash Oate epee 1, Strain 925. 7 Crace 2 Inbred 978+8 Rp'brid 5. Inbred 945. 9 RPhri4 4 Inbred 1005 7 RPbr Ql 5 ~te 1075, 7 Leg (222-%)e 1041 *6 (50. %) lCLO 8 (39. %} 996. 9 (8. 4) 1055 6 124... 28 15, 89 1. 84 4. 50 21. 62 180 1, 90 3 99 21e78 178 Table 11 is included in this study to allov a more corn piete determ~tion of the f~ effects of the previously described pxocedures and results ~ After the pullets vere placed ~ laying cages a...

  12. Measurement of the Neutron Radius of 208Pb Through Parity-Violation in Electron Scattering

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Abrahamyan, Sergey; Albataineh, Hisham; Aniol, Konrad; Armstrong, David; Armstrong, Whitney; Averett, Todd; Babineau, Benjamin; Barbieri, A; Bellini, Vincenzo; Beminiwattha, Rakitha; Benesch, Jay; Benmokhtar, Fatiha; Bierlarski, Trevor; Boeglin, Werner; Camsonne, Alexandre; Canan, Mustafa; Carter, Philip; Cates, Gordon; Chen, Chunhua; Chen, Jian-Ping; Hen, O; Cusanno, Francesco; Dalton, Mark; De Leo, Raffaele; De Jager, Cornelis; Deconinck, Wouter; Decowski, Piotr; Deng, Xiaoyan; Deur, Alexandre; Dutta, Dipangkar; Etile, Asenath; Flay, David; Franklin, Gregg; Friend, Megan; Frullani, Salvatore; Fuchey, Eric; Garibaldi, Franco; Gasser, Estelle; Gilman, Ronald; Guisa, Antonio; Glamazdin, Oleksandr; Gomez, Javier; Grames, Joseph; Gu, Chao; Hansen, Jens-Ole; Hansknecht, John; Higinbotham, Douglas; Holmes, Richard; Holmstrom, Timothy; Horowitz, Charles; Hoskins, Joshua; Huang, Jin; Hyde, Charles; Itard, Florian; Jen, Chun-Min; Jensen, Eric; Jin, Ge; Johnston, Sereres; Kelleher, Aidan; Kliakhandler, Konstantin; King, Paul; Kowalski, Stanley; Kumar, Krishna; Leacock, John; Leckey, John; Lee, Jeong Han; LeRose, John; Lindgren, Richard; Liyanage, Nilanga; Lubinsky, Nicholas; Mammei, Juliette; Mammoliti, Francesco; Margaziotis, Demetrius; Markowitz, Pete; McCreary, Amber; McNulty, Dustin; Mercado, Luis; Meziani, Zein-Eddine; Michaels, Robert; Mihovilovic, Miha; Muangma, Navaphon; Munoz Camacho, Carlos; Nanda, Sirish; Nelyubin, Vladimir; Nuruzzaman,; Oh, Yongseok; Palmer, Alvin; Parno, Diana; Paschke, Kent; Phillips, Sarah; Poelker, Benard; Pomatsalyuk, Roman; Posik, Matthew; Puckett, Andrew; Quinn, Brian; Rakhman, A; Reimer, Paul; Riordan, Seamus; Rogan, Patrick; Ron, Guy; Russo, Guiseppe; Saenboonruang, Kiadtisak; Saha, Arunava; Sawatzky, Bradley; Shahinyan, Albert; Silwal, Rupesh; Sirca, Simon; Slifer, Karl; Solvignon-Slifer, Patricia; Souder, Paul; Leda Sperduto, Maria; Subedi, Ramesh; Suleiman, Riad; Sulkosky, Vincent; Sutera, Concetta; Tobias, William; Troth, Wolfgang; Urciuoli, Guido; Buddhini Waidyawansa, Dinayadura; Wang, Diancheng; Wexler, Jonathan; Wilson, Richard; Wojtsekhowski, Bogdan; Yan, Xinhu; Yao, Huan; Ye, Yunxiu; Ye, Zhiohong; Yim, Vireak; Zana, Lorenzo; Zhan, Xiaohui; Zhang, Jixie; Zhang, Y; Zheng, Xiaochao; Zhu, Pengjia

    2012-03-15T23:59:59.000Z

    We report the first measurement of the parity-violating asymmetry APV in the elastic scattering of polarized electrons from 208Pb. APV is sensitive to the radius of the neutron distribution (Rn). The result APV = 0.656 ± 0.060 (stat) ± 0.013 (syst) corresponds to a difference between the radii of the neutron and proton distributions Rn-Rp = 0.33-0.18+0.16 fm and provides the first electroweak observation of the neutron skin which is expected in a heavy, neutron-rich nucleus.

  13. Savannah River Site environmental report for 1988

    SciTech Connect (OSTI)

    Cummins, C.L.; Hetrick, C.S.; Stevenson, D.A. (eds.); Davis, H.A.; Martin, D.K.; Todd, J.L.

    1989-01-01T23:59:59.000Z

    This volume of Savannah River Site Environmental report for 1988 (WSRC-RP-89-59-1) contains the figures and tables referenced in Volume 1. The figures contain graphic illustrations of sample locations and/or data. The tables contain summaries of the following types of data: Federal and State standards and guides applicable to SRS operations; concentrations of radioactivity in environmental media; the quantity of radioactivity released to the environment from SRS operations; offsite radiation dose commitments from SRS operations; measurements of physical properties, chemicals, and metals concentrations in environmental media; and interlaboratory comparison of analytical results.

  14. Generating Triangulated Macromolecular Surfaces by Euclidean Distance Transform

    E-Print Network [OSTI]

    Xu, Dong; Zhang, Yang

    2009-12-02T23:59:59.000Z

    are called VVW , VSAand VMS separately. Step I. Translate and scale the coordinates of all the atoms in the molecular structure in order to fit them in the bounding box. After scaling, the van der Waals radius ri and the probe radius rp become sri and srp... surface, set the radius to be the summation of sri and srp. Use the space-filling method to get the scaled volumetric solid VSA. Step III. To get the van der Waals surface and the solvent- accessible surface, go to step IV directly. To get the molecular...

  15. Feasibility Study for the K-Area Bingham Pump Outage Pit (643-1G)

    SciTech Connect (OSTI)

    Palmer, E.R. [Westinghouse Savannah River Company, AIKEN, SC (United States)

    1997-05-01T23:59:59.000Z

    The K-Area Bingham Pump Outage Pit (KBPOP) is one of four BPOP areas at Savannah River Site (SRS), collectively referred to as the BPOP waste unit group. This Feasibility Study (FS) of Remedial Alternatives serves as the lead FS for the BPOP waste unit group. This section identifies the purpose and scope of the FS and presents site background information summarized from the Final Remedial Investigation Report with Baseline Risk Assessment (RI/BRA) WSRC-RP- 95-1555, Rev. 1.2 (WSRC 1997).

  16. Grip Issue 24

    E-Print Network [OSTI]

    Multiple Contributors

    1986-01-01T23:59:59.000Z

    . ! Lament of the Ghostly Crewman, filksong by Gayle Puhl ................ 2 Star-Mapping, bM Tom L~lli ........................................... 3 Civil Obedience, by Barbara Robot%son ................................ 6 A Fighting Chance, poem by Caro.... Prin~ed a~ Insty-Prin~, Route 17 Sou~h~ Parmmus, ~t~HAT’S NEW AT OTHER WORLDS BOOKS S~ner 1986 <~R~P ~25, Feorua%~ 1986: A Star Trek novella, waZch placG5 Ki~k in L~e clutca~ of vicious A~ens, leav~[ng Scott~ ~ cope in .the ai~ :..,~.~e S~oc~, ~;~a...

  17. Magnetization relaxation in (Ga,Mn)As ferromagnetic semiconductors

    E-Print Network [OSTI]

    Sinova, Jairo; Jungwirth, T.; Liu, X.; Sasaki, Y.; Furdyna, JK; Atkinson, WA; MacDonald, AH.

    2004-01-01T23:59:59.000Z

    - ?As ferromagnetic semiconductors Furdyna,4,3 W. A. Atkinson,5 and A. H. MacDonald3 y, College Station, Texas 77843-4242, USA a? 10, 162 53 Praha 6, Czech Republic at Austin, Austin, Texas 78712-0264, USA Dame, Notre Dame, Indiana 46556, USA y...-quality samples, due to the coupling of the d-level local moments to 5 Donald, Phys. Rev. B 66, 012402 ~2002!; K.W. Edmonds, K.Y. Wang, R.P. Campion, A.C. Neumann, C.T. Foxon, B.L. Gal- lagher, and P.C. Main, Appl. Phys. Lett. 81, 3010 ~2002!. 8 and A. Fert...

  18. The dc modeling program (DCMP): Version 2. 0

    SciTech Connect (OSTI)

    Chapman, D.G. (Manitoba HVDC Research Centre, Winnipeg, MB (Canada))

    1990-08-01T23:59:59.000Z

    In this project one of the main objectives was the refinement of tools for the study of HVDC systems. The original software was prepared in project RP1964-2 (EL-4365) as power flow and stability program models for HVDC systems. In this project new modeling capabilities were added to both the power flow and stability models. Additionally, the HVDC specific model capabilities were integrated into a new program, termed the Standalone program, for use in the development and testing of HVDC models.

  19. HVDC system control for damping subsynchronous oscillations

    SciTech Connect (OSTI)

    Piwko, R.J.; Larsen, E.V.

    1982-07-01T23:59:59.000Z

    A method for designing a supplemental subsynchronous damping control (SSDC) for an HVDC transmission system is described. The SSDC eliminates torsional instabilities caused by interaction between conventional HVDC controls and turbine-generator rotor torsional modes of vibration. Results of digital simulation used in the design process are compared with measurements made on an HVDC simulator. Results of both digital simulations and HVDC simulator tests which demonstrate SSDC performance are shown. This research and development effort was sponsored by EPRI under RP1425-1.

  20. The dc modeling program (DCMP): Version 2. 0

    SciTech Connect (OSTI)

    Chapman, D.G. (Manitoba HVDC Research Centre, Winnipeg, MB (Canada))

    1990-08-01T23:59:59.000Z

    In this project one of the main objectives was the refinement of tools for the study of HVDC systems. The original software was prepared in project RP1964-2 (EL-4365) as power flow and stability program models for HVDC systems. In this project new modeling capabilities were added to both the power flow and stability models. Additionally, the HVDC specific model capabilities were integrated into a new program, termed the Standalone program, for use in the development and testing of HVDC models. This volume provides information on the application of the software in the form of a User's Manual.

  1. The dc modeling program (DCMP): Version 2. 0

    SciTech Connect (OSTI)

    Chapman, D.G. (Manitoba HVDC Research Centre, Winnipeg, MB (Canada))

    1990-08-01T23:59:59.000Z

    In this project one of the main objectives was the refinement of tools for the study of HVDC systems. The original software was prepared in project RP1964-2 (EL-4365) as power flow and stability program models for HVDC systems. In this project new modeling capabilities were added to both the power flow and stability models. Additionally, the HVDC specific model capabilities were integrated into a new program, termed the Standalone program, for use in the development and testing of HVDC models. This manual provides technical background for programmers and those interested in understanding, augmenting or transporting the dc models.

  2. Thermonuclear reaction rate of $^{18}$Ne($?$,$p$)$^{21}$Na from Monte-Carlo calculations

    E-Print Network [OSTI]

    P. Mohr; R. Longland; C. Iliadis

    2014-12-14T23:59:59.000Z

    The $^{18}$Ne($\\alpha$,$p$)$^{21}$Na reaction impacts the break-out from the hot CNO-cycles to the $rp$-process in type I X-ray bursts. We present a revised thermonuclear reaction rate, which is based on the latest experimental data. The new rate is derived from Monte-Carlo calculations, taking into account the uncertainties of all nuclear physics input quantities. In addition, we present the reaction rate uncertainty and probability density versus temperature. Our results are also consistent with estimates obtained using different indirect approaches.

  3. Thermonuclear reaction rate of $^{18}$Ne($\\alpha$,$p$)$^{21}$Na from Monte-Carlo calculations

    E-Print Network [OSTI]

    Mohr, P; Iliadis, C

    2014-01-01T23:59:59.000Z

    The $^{18}$Ne($\\alpha$,$p$)$^{21}$Na reaction impacts the break-out from the hot CNO-cycles to the $rp$-process in type I X-ray bursts. We present a revised thermonuclear reaction rate, which is based on the latest experimental data. The new rate is derived from Monte-Carlo calculations, taking into account the uncertainties of all nuclear physics input quantities. In addition, we present the reaction rate uncertainty and probability density versus temperature. Our results are also consistent with estimates obtained using different indirect approaches.

  4. The influence of flowable sulfur on controlled-release of NPK fertilizers

    E-Print Network [OSTI]

    Tammakrut, Somkid

    1983-01-01T23:59:59.000Z

    were determined in the laboratory. Wheat plants were grown in the greenhouse to investigate N and P availability in acid and limed Lufkin soil from the urea and DAP products as well as the effect of S in a rock phosphate sulfur suspension (RP... Page Dry matter yield of wheat plant from two harvests as affected by TSP and DAP fer- tilizers incubated in acid or limed soil 6 weeks before planting. (Bars within an array having the same letters are not significantly different at P = . 05...

  5. Meters

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Science (SC)Integrated Codes |IsLove Your HomeOverview and HistoryMEMS: Inside theand RP-1

  6. Quantitative assessment of computational models for retinotopic map formation

    E-Print Network [OSTI]

    Hjorth, J. J. Johannes; Sterratt, David C.; Cutts, Catherine S.; Willshaw, David J.; Eglen, Stephen J.

    2014-11-14T23:59:59.000Z

    and summarized in Table 2. Number and Placement of Neurons. In mouse, there are around 50,000 RGCs (Jeon et al., 1998; Salinas-Navarro et al., 2009), and an unknown number of SC neurons. Here, networks containing 2,000 retinal neurons (NR) and 2,000 SC neurons... . However, with around 50,000 RGCs (Jeon et al., 1998; Salinas-Navarro et al., 2009), and 12–22 subtypes (Sun et al., 2002; Kong et al., 2005; V€olgyi et al., 2009; S€umb€ul et al., 2014), there might be around 2,300–4,200 of each RGC type, each poten...

  7. Science and technology of biocompatible thin films for implantable biomedical devices.

    SciTech Connect (OSTI)

    Li, W.; Kabius, B.; Auciello, O.; Materials Science Division

    2010-01-01T23:59:59.000Z

    This presentation focuses on reviewing research to develop two critical biocompatible film technologies to enable implantable biomedical devices, namely: (1) development of bioinert/biocompatible coatings for encapsulation of Si chips implantable in the human body (e.g., retinal prosthesis implantable in the human eye) - the coating involves a novel ultrananocrystalline diamond (UNCD) film or hybrid biocompatible oxide/UNCD layered films; and (2) development of biocompatible films with high-dielectric constant and microfabrication process to produce energy storage super-capacitors embedded in the microchip to achieve full miniaturization for implantation into the human body.

  8. Fastcast: Integration and application of rapid prototyping and computational simulation to investment casting

    SciTech Connect (OSTI)

    Maguire, M.C.; Baldwin, M.D.; Atwood, C.L.

    1996-09-01T23:59:59.000Z

    The emergence of several rapid prototyping and manufacturing (RP and M) technologies is having a dramatic impact on investment casting. While the most successful of the rapid prototyping technologies are almost a decade old, relatively recent process advances in their application have produced some remarkable success in utilizing their products as patterns for investment castings. Sandia National Laboratories has been developed highly coupled experimental and computational capabilities to examine the investment casting process with the intention of reducing the amount of time required to manufacture castings, and to increase the quality of the finished product. This presentation will begin with process aspects of RP and M pattern production and handling, shell fabrication, burnout, and casting. The emphasis will be on how the use of Stereolithography (SL) or Selective Laser Sintered (SLS) patterns differs from more traditional wax pattern processes. Aspects of computational simulation to couple design, thermal analysis, and mold filling will be discussed. Integration of these topics is probably the greatest challenge to the use of concurrent engineering principles with investment casting. Sandia has conducted several experiments aimed at calibrating computer codes and providing data for input into these simulations. Studies involving materials as diverse as stainless steel and gold have been conducted to determine liquid metal behavior in molds via real time radiography. The application of these experiments to predictive simulations will be described.

  9. Weak charge form factor and radius of 208Pb through parity violation in electron scattering

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Horowitz, C J; Jen, C -M; Rakhman, A; Souder, P A; Dalton, M M; Liyanage, N; Paschke, K D; Saenboonruang, K; Silwal, R; Franklin, G B; Friend, M; Quinn, B; Kumar, K S; McNulty, D; Mercado, L; Riordan, S; Wexler, J

    2012-03-26T23:59:59.000Z

    We use distorted wave electron scattering calculations to extract the weak charge form factor FW(q?), the weak charge radius RW, and the point neutron radius Rn, of 208Pb from the PREX parity violating asymmetry measurement. The form factor is the Fourier transform of the weak charge density at the average momentum transfer q? = 0.475 fm-1. We find FW(q?) = 0.204 ± 0.028(exp) ± 0.001(model). We use the Helm model to infer the weak radius from FW(q?). We find RW = 5.826 ± 0.181(exp) ± 0.027(model) fm. Here the exp error includes PREX statistical and systematic errors, while the model error describes the uncertainty in RW from uncertainties in the surface thickness ? of the weak charge density. The weak radius is larger than the charge radius, implying a 'weak charge skin' where the surface region is relatively enriched in weak charges compared to (electromagnetic) charges. We extract the point neutron radius Rn = 5.751 ± 0.175 (exp) ± 0.026(model) ± 0.005(strange) fm, from RW. Here there is only a very small error (strange) from possible strange quark contributions. We find Rn to be slightly smaller than RW because of the nucleon's size. Finally, we find a neutron skin thickness of Rn-Rp = 0.302 ± 0.175 (exp) ± 0.026 (model) ± 0.005 (strange) fm, where Rp is the point proton radius.

  10. Epidemiological-environmental study of diesel bus garage workers: acute effects of NO/sub 2/ and respirable particulate on the respiratory system

    SciTech Connect (OSTI)

    Gamble, J.; Jones, W.; Minshall, S.

    1987-02-01T23:59:59.000Z

    Personal samples of nitrogen dioxide (NO/sub 2/) and respirable particulate (RP) were collected over the shift on 232 workers in four diesel bus garages. Response was assessed by an acute respiratory questionnaire and before and after shift spirometry. Measures of exposure to NO/sub 2/ and RP were associated with work-related symptoms of cough; itching, burning, or watering eyes; difficult or labored breathing; chest tightness; and wheeze. The prevalence of burning eyes, headaches, difficult or labored breathing, nausea, and wheeze experienced at work were higher in the diesel bus garage workers than in a comparison population of battery workers, while the prevalence of headaches was reduced. Mean reductions in forced vital capacity (FVC), forced expiratory volume in 1 sec (FEV1), peak flow, and flows at 50 and 75% of FVC were not obviously different from zero. There was no detectable association of exposure to NO/sub 2/ or respirable particulate and acute reductions in pulmonary function. Workers who often had respiratory work-related symptoms generally had a slightly greater mean acute reduction in FEV1 and FEF50 than did those who did not have these symptoms, but these differences were not statistically significant.

  11. An epidemiological study of salt miners in diesel and nondiesel mines

    SciTech Connect (OSTI)

    Gamble, J.; Jones, W.; Hudak, J.

    1983-01-01T23:59:59.000Z

    A cross-sectional study of 5 NaCl mines and 259 miners addressed the following questions: 1) Is there an association of increased respiratory symptoms, radiographic findings, and reduced pulmonary function with exposure to nitrogen dioxide (NO2) and/or respirable particulate (RP) among these miners. 2) Is there increased morbidity of these miners compared to other working populations. Personal samples of NO2 and respirable particulate for jobs in each mine were used to estimate cumulative exposure. NO2 is used as a surrogate measure of diesel exposure. Cough was associated with age and smoking, dyspnea with age; neither symptom was associated with exposure (years worked, estimated cumulative NO2 or RP exposure). Phlegm was associated with age, smoking, and exposure. Reduced pulmonary function (FVC, FEV1, peak, flow, FEF50, FEF75) showed no association with exposure. There was one case of small rounded and one case of small irregular opacities; pneumoconiosis was not analyzed further. Compared to underground coal miners, above ground coal miners, potash miners, and nonmining workers, the study population after adjustment for age and smoking generally showed no increased prevalence of cough, phlegm, dyspnea, or obstruction (FEV1/FVC less than 0.7). Obstruction in younger salt miners and phlegm in older salt miners was elevated compared to nonmining workers. Mean predicted pulmonary function was reduced 2-4% for FEV1 and FVC, 7-13% for FEF50, and 18-22% for FEF75 below all comparison populations.

  12. Testing the mirror world hypothesis for the close-in extrasolar planets

    E-Print Network [OSTI]

    R. Foot

    2004-06-10T23:59:59.000Z

    Because planets are not expected to be able to form close to stars due to the high temperatures, it has been suggested that the observed close orbiting ($\\sim 0.05$ AU) large mass planets ($\\sim M_J$) might be mirror worlds -- planets composed predominately of mirror matter. The accretion of ordinary matter onto the mirror planet (from e.g. the solar wind from the host star) will make the mirror planet opaque to ordinary radiation with an effective radius $R_p$. It was argued in a previous paper, astro-ph/0101055, that this radius was potentially large enough to explain the measured size of the first transiting close-in extrasolar planet, HD209458b. Furthermore, astro-ph/0101055, made the rough prediction: $R_p \\propto \\sqrt{{T_s \\over M_p}}$, where $T_s$ is the surface temperature of the ordinary matter in the mirror planet and $M_p$ is the mass of the planet (the latter dependence being the more robust prediction). We compare this prediction with the recently discovered transiting planets, OGLE-TR-56b and OGLE-TR-113b.

  13. Weak charge form factor and radius of 208Pb through parity violation in electron scattering

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Horowitz, C J; Jen, C -M; Rakhman, A; Souder, P A; Dalton, M M; Liyanage, N; Paschke, K D; Saenboonruang, K; Silwal, R; Franklin, G B; et al

    2012-03-01T23:59:59.000Z

    We use distorted wave electron scattering calculations to extract the weak charge form factor FW(q?), the weak charge radius RW, and the point neutron radius Rn, of 208Pb from the PREX parity violating asymmetry measurement. The form factor is the Fourier transform of the weak charge density at the average momentum transfer q? = 0.475 fm-1. We find FW(q?) = 0.204 ± 0.028(exp) ± 0.001(model). We use the Helm model to infer the weak radius from FW(q?). We find RW = 5.826 ± 0.181(exp) ± 0.027(model) fm. Here the exp error includes PREX statistical and systematic errors, while the modelmore »error describes the uncertainty in RW from uncertainties in the surface thickness ? of the weak charge density. The weak radius is larger than the charge radius, implying a 'weak charge skin' where the surface region is relatively enriched in weak charges compared to (electromagnetic) charges. We extract the point neutron radius Rn = 5.751 ± 0.175 (exp) ± 0.026(model) ± 0.005(strange) fm, from RW. Here there is only a very small error (strange) from possible strange quark contributions. We find Rn to be slightly smaller than RW because of the nucleon's size. Finally, we find a neutron skin thickness of Rn-Rp = 0.302 ± 0.175 (exp) ± 0.026 (model) ± 0.005 (strange) fm, where Rp is the point proton radius.« less

  14. Possible observables for the chiral electric separation effect in Cu + Au collisions

    E-Print Network [OSTI]

    Guo-Liang Ma; Xu-Guang Huang

    2015-05-21T23:59:59.000Z

    The quark-gluon plasma (QGP) generated in relativistic heavy-ion collisions could be locally parity-odd. In parity-odd QGP, the electric field may induce a chiral current which is called the chiral electric separation effect (CESE). We propose two possible observables for CESE in Cu + Au collisions: The first one is the correlation $\\zeta_{\\alpha\\beta}=\\langle \\cos[2(\\phi_\\alpha+\\phi_\\beta-2\\Psi_{\\rm RP})]\\rangle$; the second one is the charge-dependent event-plane angle $\\Psi^{q}_2$ with $q=\\pm$ being charge. Nonzero $\\Delta\\zeta=\\zeta_{opp}-\\zeta_{same}$ and $\\Delta\\Psi=\\langle|\\Psi_2^+-\\Psi_2^-|\\rangle$ may signal the CESE in Cu + Au collisions. Within a multiphase transport model, we study how the final state interaction affects these observables. We find that the correlation $\\gamma_{\\alpha\\beta}=\\langle\\cos(\\phi_{\\alpha}+\\phi_{\\beta}-\\Psi_{\\rm RP})\\rangle$ is sensitive to the out-of-plane charge separation caused by the chiral magnetic effect and to the in-plane charge separation caused by the in-plane electric field, but it is not sensitive to the CESE. On the other hand, $\\Delta\\zeta$ and $\\Delta\\Psi$ are sensitive to the CESE. Therefore, we suggest that the future experiments measure the above observables in Cu+Au collisions in order to disentangle different chiral and charge separation mechanisms.

  15. Salvage/Adjuvant Brachytherapy After Ophthalmic Artery Chemosurgery for Intraocular Retinoblastoma

    SciTech Connect (OSTI)

    Francis, Jasmine H., E-mail: francij1@mskcc.org [Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Barker, Christopher A.; Wolden, Suzanne L.; McCormick, Beryl; Segal, Kira; Cohen, Gil [Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Gobin, Y. Pierre; Marr, Brian P. [Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Weill-Cornell Medical College, New York-Presbyterian Hospital, New York, New York (United States); Brodie, Scott E. [Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Mount Sinai School of Medicine, New York, New York (United States); Dunkel, Ira J.; Abramson, David H. [Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Weill-Cornell Medical College, New York-Presbyterian Hospital, New York, New York (United States)

    2013-11-01T23:59:59.000Z

    Purpose: To evaluate the efficacy and toxicity of brachytherapy after ophthalmic artery chemosurgery (OAC) for retinoblastoma. Methods and Materials: This was a single-arm, retrospective study of 15 eyes in 15 patients treated with OAC followed by brachytherapy at (blinded institution) between May 1, 2006, and December 31, 2012, with a median 19 months' follow-up from plaque insertion. Outcome measurements included patient and ocular survival, visual function, and retinal toxicity measured by electroretinogram (ERG). Results: Brachytherapy was used as adjuvant treatment in 2 eyes and as salvage therapy in 13 eyes of which 12 had localized vitreous seeding. No patients developed metastasis or died of retinoblastoma. The Kaplan-Meier estimate of ocular survival was 79.4% (95% confidence interval 48.7%-92.8%) at 18 months. Three eyes were enucleated, and an additional 6 eyes developed out-of-target volume recurrences, which were controlled with additional treatments. Patients with an ocular complication had a mean interval between last OAC and plaque of 2.5 months (SD 2.3 months), which was statistically less (P=.045) than patients without ocular complication who had a mean interval between last OAC and plaque of 6.5 months (SD 4.4 months). ERG responses from pre- versus postplaque were unchanged or improved in more than half the eyes. Conclusions: Brachytherapy following OAC is effective, even in the presence of vitreous seeding; the majority of eyes maintained stable or improved retinal function following treatment, as assessed by ERG.

  16. Patterns and Predictors of Early Biochemical Recurrence After Radical Prostatectomy and Adjuvant Radiation Therapy in Men With pT{sub 3}N{sub 0} Prostate Cancer: Implications for Multimodal Therapies

    SciTech Connect (OSTI)

    Briganti, Alberto, E-mail: briganti.alberto@hsr.it [Department of Urology, San Raffaele Scientific Institute, Vita-Salute University, Milan (Italy); Joniau, Steven [Department of Urology, University Hospitals Leuven, Leuven (Belgium); Gandaglia, Giorgio [Department of Urology, San Raffaele Scientific Institute, Vita-Salute University, Milan (Italy); Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal (Canada); Cozzarini, Cesare [Department of Radiotherapy, San Raffaele Scientific Institute, Milan (Italy); Sun, Maxine [Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal (Canada); Tombal, Bertrand [Department of Urology, Université Catholique de Louvain, Brussels (Belgium); Haustermans, Karin [Department of Radiology, University Hospitals Leuven, Leuven (Belgium); Hinkelbein, Wolfgang [Department of Radiation Oncology, Charité Universitätsmedizin, Campus Benjamin Franklin, Berlin (Germany); Shariat, Shahrokh F. [Department of Urology, University of Vienna, Vienna (Austria); Karakiewicz, Pierre I. [Cancer Prognostics and Health Outcomes Unit, University of Montreal, Montreal (Canada); Montorsi, Francesco [Department of Urology, San Raffaele Scientific Institute, Vita-Salute University, Milan (Italy); Van Poppel, Hein [Department of Urology, University Hospitals Leuven, Leuven (Belgium); Wiegel, Thomas [Department of Radiation Oncology, University Hospital Ulm, Ulm (Germany)

    2013-12-01T23:59:59.000Z

    Purpose: The aim of our study was to evaluate patterns and predictors of early biochemical recurrence (eBCR) after radical prostatectomy (RP) and adjuvant radiation therapy (aRT) in order to identify which individuals might benefit from additional treatments. Methods and Materials: We evaluated 390 patients with pT{sub 3}N{sub 0} prostate cancer (PCa) receiving RP and aRT at 6 European centers between 1993 and 2006. Patients who were free from BCR at <2 years' follow-up were excluded. This resulted in 374 assessable patients. Early BCR was defined as 2 consecutive prostate-specific antigen (PSA) test values >0.2 ng/mL within 2 or 3 years after aRT. Uni- and multivariable Cox regression analyses predicting overall and eBCR after aRT were fitted. Covariates consisted of preoperative PSA results, surgical margins, pathological stage, Gleason score, and aRT dose. Results: Overall, 5- and 8-year BCR-free survival rates were 77.1% and 70.8%, respectively. At a median follow-up of 86 months after aRT, 33 (8.8%) and 55 (14.6%) men experienced BCR within 2 or 3 years after aRT, respectively. In multivariable analyses, Gleason scores of 8 to 10 represented the only independent predictor of eBCR after aRT (all, P?.01). The risk of BCR was significantly higher in patients with a Gleason score of 8 to 10 disease than in those with Gleason 2 to 6 within 24 months after treatment, after adjusting for all covariates (all, P?.04). However, given a 24-month BCR free period, the risk of subsequent BCR for men with poorly differentiated disease was equal to that of men with less aggressive disease (all, P?.3). Conclusions: High Gleason score represents the only predictor of eBCR after RP and aRT in patients affected by pT{sub 3}N{sub 0} PCa. Given the association between early PSA recurrence, clinical progression, and mortality, these patients might be considered candidates for adjuvant medical therapy and/or prophylactic whole-pelvis radiation therapy in addition to aRT, delivered to the prostatic bed.

  17. Marketing aspects of range sheep production in Texas

    E-Print Network [OSTI]

    Blackwell, James Wayne

    1958-01-01T23:59:59.000Z

    Ma]er sub)sots Agricultural goonIELo? LISRRRY I 4 M COLLEGE OF TEXlg iV:~"tiffin A% 'OI, : QV . W't~~': 3. .:"%'9 P-'-. QD'~7'iXC4 31i 'i'm'. A3 tune~ Ozbnttte~ to the Graduate School of tlat l~icultuxal and Hechanica1 College ef 'exaa fn ce... of Cased. ttes / c3 ~ Head Dapartawnt August, 195S Vtikl B'l% -'W' W~~'. ~ ". . i'P uO 9~~"'988 &8 RpD~CXSVJ. QB CO . :1' ~ iBTWig . ~ . "~sr @ha g~avw Zrs~Q a. 1k@ '. Em a~& !s, "~led'a M helotry? wt ~ t-e i'd ~ 'MpO~' ~ 8100 NRi~/ 3 QSBk8 8' 8...

  18. Analysis of ocean waves and wave forces by a filtering technique

    E-Print Network [OSTI]

    Blumberg, Randolph

    1955-01-01T23:59:59.000Z

    ?? oipp? i?t?a?? t?? t?jp ?ty? p???? ?????? ???pbit??r???? a AHHLTT 6????6?? ??? p? ??? oiarti? oip???rj ?p??ip??a?? ??? ?ptj?t? engineer is ??? ?j?t??aj?r??? p? t i?oip?b?a??? i??t?ap?j?ao ??????? ??? ???ip??? ?tra? ?pi??j ???i??? p? t rtia?? j...?tjbi?? a? ??? ?a???? ?p??y?i? ti? y?i? ?pro??? a? ??tit???i? and ??? i??t?ap?j tj ?j?t??aj??? a? ??? ?t?pit?pi? ti? a?t???bt?? ???tbj? p? ??aj ?pro???a??? 6 rt???rt?a?t? ?i??b??????a???ia?? j?j??r aj ??y??po?? a? ??aj j?b?? ?p oipya?? t r???p? p? i?jp...

  19. GRIMHX verification and validation action matrix summary

    SciTech Connect (OSTI)

    Trumble, E.F.

    1991-12-01T23:59:59.000Z

    WSRC-RP-90-026, Certification Plan for Reactor Analysis Computer Codes, describes a series of action items to be completed for certification of reactor analysis computer codes used in Technical Specifications development and for other safety and production support calculations. Validation and verification of the code is an integral part of this process. This document identifies the work performed and documentation generated to satisfy these action items for the Reactor Physics computer code GRIMHX. Each action item is discussed with the justification for its completion. Specific details of the work performed are not included in this document but are found in the references. The publication of this document signals the validation and verification effort for the GRIMHX code is completed.

  20. Regge behavior saves String Theory from causality violations

    E-Print Network [OSTI]

    D'Appollonio, Giuseppe; Russo, Rodolfo; Veneziano, Gabriele

    2015-01-01T23:59:59.000Z

    Higher-derivative corrections to the Einstein-Hilbert action are present in bosonic string theory leading to the potential causality violations recently pointed out by Camanho et al. We analyze in detail this question by considering high-energy string-brane collisions at impact parameters $b \\le l_s$ (the string-length parameter) with $l_s \\gg R_p$ (the characteristic scale of the D$p$-brane geometry). If we keep only the contribution of the massless states causality is violated for a set of initial states whose polarization is suitably chosen with respect to the impact parameter vector. Such violations are instead neatly avoided when the full structure of string theory - and in particular its Regge behavior - is taken into account.