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Note: This page contains sample records for the topic "respiratory disease orthopedic" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


1

LANL spinoff receives NIH grant for respiratory disease diagnostic device  

NLE Websites -- All DOE Office Websites (Extended Search)

LANL spinoff receives NIH grant LANL spinoff receives NIH grant LANL spinoff receives NIH grant for respiratory disease diagnostic device Mesa Tech has been awarded a grant to develop an inexpensive, instrument-free, nucleic-acid testing device to diagnose various respiratory diseases in record time. October 19, 2011 Los Alamos National Laboratory sits on top of a once-remote mesa in northern New Mexico with the Jemez mountains as a backdrop to research and innovation covering multi-disciplines from bioscience, sustainable energy sources, to plasma physics and new materials. Los Alamos National Laboratory sits on top of a once-remote mesa in northern New Mexico with the Jemez mountains as a backdrop to research and innovation covering multi-disciplines from bioscience, sustainable energy

2

Mortality from heart, respiratory, and kidney disease in coal mining areas of Appalachia  

Science Journals Connector (OSTI)

The purpose of this study was to test whether population mortality rates from heart, respiratory and kidney disease were higher as a function of levels of Appalachian coal mining after control for other diseas...

Michael Hendryx

2009-01-01T23:59:59.000Z

3

Respiratory disease and particulate air pollution in Santiago Chile: Contribution of erosion particles from fine sediments  

E-Print Network (OSTI)

August) that make atmospheric conditions highly vulnerable, preventing polluting particles in the airCommentary Respiratory disease and particulate air pollution in Santiago Chile: Contribution pollution Santiago Erosion Sedimentation a b s t r a c t Air pollution in Santiago is a serious problem

4

E-Print Network 3.0 - allergic respiratory diseases Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

a health and safety program... ) Hard hat Goggles Hearing protectors Safety boots T-shirts with 4 inch sleeves Respiratory... , including allergic rhinitis (a...

5

Identification and characterization of a virus isolated from bobwhite quail with a respiratory disease  

E-Print Network (OSTI)

. Observations were made on the chicken embryo mortality pat- tern, dwarfing and the gross lesions of necropsicd embryos in the reisolations of;"QV and CZLO virus, tne filtration of CZLO virus, in straight passages (/th through lith) of 2 field strains 17... and 8 days after inoculation in CELO Group I. It was usually unilateral and usually, but not clways, on the side of the intraocular inoculation. Nasal discharge could not, be di. s- cerned while the quail were in the 'brooder. Respiratory symptoms in:QV...

DuBose, Robert Trafton

2012-06-07T23:59:59.000Z

6

Effects of Air Pollution on Respiratory Disease Asthma, closely associated with air pollution, affects nearly 15 million people in the United States, one-third of them  

E-Print Network (OSTI)

dimension to our understanding the health effects of air pollution. Contact: Trina Wood, (530) 752-5257 3Effects of Air Pollution on Respiratory Disease Asthma, closely associated with air pollution as a greater understanding of the types of air pollutants that cause the most harm. Seminal findings

Schladow, S. Geoffrey

7

Respiratory Enzymes  

Science Journals Connector (OSTI)

... the experimental work leading up to them and shows the manner in which they are interrelated. Much of the relevant information which has been summarized so far, is to be ... , flavoproteins, etc., an article on the specific and non-specific poisons of respiratory processes and one on hydrogen transport systems. Finally, there are useful chapters on oxidation-reduction ...

J. H. Q.

1939-12-16T23:59:59.000Z

8

E-Print Network 3.0 - adult respiratory distress Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

syndrome. Ameri- can Review of Respiratory Disease... . Objectives To ... Source: Solomon, Patty - School of Mathematical Sciences, University of Adelaide Collection:...

9

Respiratory tract infections in the military environment  

Science Journals Connector (OSTI)

Abstract Military personnel fighting in contemporary battlefields as well as those participating in combat training are at risk of contracting respiratory infections. Epidemiological studies have demonstrated that soldiers deployed to the harsh environment have higher rates of newly reported respiratory symptoms than non-deployers. Acute respiratory diseases are the principle reason for outpatient treatment and hospitalization among military personnel, with an incidence exceeding that of the adult civilian population by up to three-fold. Adenoviruses, influenza A and B viruses, Streptococcus pneumoniae, Streptococcus pyogenes, coronaviruses and rhinoviruses have been identified as the main causes of acute respiratory infections among the military population. Although infective pathogens have been extensively studied, a significant proportion of illnesses (over 40%) have been due to unknown causative agents. Other health hazards, which can lead to respiratory illnesses among troops, are extreme air temperatures, desert dust, emissions from burn pits, industrial pollutants, and airborne contaminants originating from degraded soil. Limited diagnostic capabilities, especially inside the area of operations, make it difficult to accurately estimate the exact number of respiratory diseases in the military environment. The aim of the study was to discuss the occurrence of respiratory tract infections in army personnel, existing risk factors and preventive measures.

Krzysztof Korzeniewski; Aneta Nitsch-Osuch; Monika Konior; Anna Lass

2014-01-01T23:59:59.000Z

10

Respiratory Protection Program  

Energy.gov (U.S. Department of Energy (DOE))

This page is supported by the Respiratory Protection Program Administrators Group. The Respiratory Protection Program Administrators Group is a volunteer organization co-sponsored by the DOE Office of Worker Safety and Health Policy and the Energy Facility Contractors Group (EFCOG) to provide a forum for DOE and DOE contractor personnel to identify respiratory protection issues of concern to the DOE and pursue solutions to issues identified.

11

About the Air Pollution and Respiratory Health Program The Air Pollution and Respiratory Health Program of the National Center for Environmental Health, Centers for  

E-Print Network (OSTI)

About the Air Pollution and Respiratory Health Program The Air Pollution and Respiratory Health public health agencies. For example, CDC staff are currently studying the effect of outdoor air pollution for Chronic Disease Prevention and Health Promotion, the Air Pollution and Respiratory Health Program supports

12

Improved performance of ultra-high molecular weight polyethylene for orthopedic applications  

E-Print Network (OSTI)

A considerable number of total-joint replacement devices used in orthopedic medicine involve articulation between a metallic alloy and ultra-high molecular weight polyethylene (UHMWPE). Though this polymer has excellent wear resistance, the wear...

Plumlee, Kevin Grant

2009-05-15T23:59:59.000Z

13

SmartCast - Novel Textile Sensors for Embedded Pressure Sensing of Orthopedic Casts  

E-Print Network (OSTI)

J. Kaiser, Chair An orthopedic plaster or fiberglass cast is1 - Introduction 1.1 Background A plaster or fiberglass castunderstand how well a plaster or fiberglass cast fits over

Danilovic, Andrew

2013-01-01T23:59:59.000Z

14

Comparative Ecology of Respiratory Mycotic Disease Agents  

Science Journals Connector (OSTI)

...Utah); Mexico (Baja California, Chihuahua, Colima, Coahuila, Durango, Guanajuato...Baja California, 32%; Sonora, 67%; Chihuahua, 37%; Colima, 33%. In a large-scale...in the states of Baja California, Chihuahua, Coahuila, Colima, Durango, Guanajuato...

Libero Ajello

1967-03-01T23:59:59.000Z

15

Bovine Respiratory Disease Max Irsik DVM, MAB  

E-Print Network (OSTI)

. The clinical signs are usually mild and involve coughing, nasal discharge, fever and a decreased appetite signs of BRD are nasal and eye discharges, coughing, fever, depressed appetite, varying degrees

Watson, Craig A.

16

Investigation of a HA/PDLGA/Carbon Foam Material System for Orthopedic Fixation Plates Based on Time-Dependent Properties  

E-Print Network (OSTI)

throughout healing while maintaining fracture stability. The primary aim of this study is to quantify the degradation rate of a bioresorbable material system, then use this degradation rate to determine the material response of an orthopedic device made...

Rodriguez, Douglas E.

2010-01-14T23:59:59.000Z

17

Multiplex detection of respiratory pathogens  

DOE Patents (OSTI)

Described are kits and methods useful for detection of respiratory pathogens (influenza A (including subtyping capability for H1, H3, H5 and H7 subtypes) influenza B, parainfluenza (type 2), respiratory syncytial virus, and adenovirus) in a sample. Genomic sequence information from the respiratory pathogens was analyzed to identify signature sequences, e.g., polynucleotide sequences useful for confirming the presence or absence of a pathogen in a sample. Primer and probe sets were designed and optimized for use in a PCR based, multiplexed Luminex assay to successfully identify the presence or absence of pathogens in a sample.

McBride, Mary (Brentwood, CA); Slezak, Thomas (Livermore, CA); Birch, James M. (Albany, CA)

2012-07-31T23:59:59.000Z

18

OmniBrace: A Fast Acting Expanding Foam Splint for Orthopedic Injuries Anisha Bapna, Margaret Lees, William Littlefield, Harrison Rose  

E-Print Network (OSTI)

utilizes expanding polyurethane foam technology to provide immediate temporary immobilization to orthopedic professionals · Emergency responders · Sports medics · Military field medics There are 225,000 registered EMS personnel in the US alone, as well as nearly 20,000 sports medics, all requiring immobilization equipment

McGaughey, Alan

19

E-Print Network 3.0 - acute radiation disease Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

illness, malaria, measles, tetanus 12... Human Transport of Disease SARS The Cough Heard Round the World Severe Acute Respiratory Syndrome 2003 1... 1 Environmental...

20

LANL spinoff receives NIH grant for respiratory disease diagnostic...  

NLE Websites -- All DOE Office Websites (Extended Search)

as a backdrop to research and innovation covering multi-disciplines from bioscience, sustainable energy sources, to plasma physics and new materials. Los Alamos National Laboratory...

Note: This page contains sample records for the topic "respiratory disease orthopedic" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


21

Dynamics of infectious disease transmission by inhalable respiratory droplets  

Science Journals Connector (OSTI)

...attributable to airborne respirable (solid line), airborne inspirable (dashed line) and settled inspirable (dotted line) droplets; number of infections...M. Wein 2008 Quantifying the routes of transmission for pandemic influenza. Bull...

2010-01-01T23:59:59.000Z

22

Ann Occup Hyg . Author manuscript Asbestos-related diseases in automobile mechanics  

E-Print Network (OSTI)

Ann Occup Hyg . Author manuscript Page /1 7 Asbestos-related diseases in automobile mechanics Abstract Purpose Automobile mechanics have been exposed to asbestos number of automobile mechanics, little is known about the non-malignant respiratory diseases observed

Paris-Sud XI, Université de

23

Disease Manifestations and Pathogenic Mechanisms of Group A Streptococcus  

Science Journals Connector (OSTI)

...streptococcal disease among household contacts of case patients and...respiratory tract pathogens in Japan. Int. J. Infect. Dis. 9...Streptococcus pyogenes isolated in Japan from patients with severe invasive...Beta-Haemolytic Streptococci in Japan. 2007. Distribution of emm...

Mark J. Walker; Timothy C. Barnett; Jason D. McArthur; Jason N. Cole; Christine M. Gillen; Anna Henningham; K. S. Sriprakash; Martina L. Sanderson-Smith; Victor Nizet

2014-04-01T23:59:59.000Z

24

Respiratory hospitalizations of children and residential exposure to traffic air pollution in Jerusalem  

Science Journals Connector (OSTI)

Abstract Although exposure to traffic-related air pollution has been reported to be associated with respiratory morbidity in children, this association has not been examined in Israel. Jerusalem is ranked among the leading Israeli cities in transport-related air pollution. This casecontrol study examined whether pediatric hospitalization for respiratory diseases in Jerusalem is related to residential exposure to traffic-related air pollution. Cases (n=4844) were Jerusalem residents aged 014 years hospitalized for respiratory illnesses between 2000 and 2006. These were compared to children admitted electively (n=2161) or urgently (n=3085) for non-respiratory conditions. Individual measures of exposure included distance from residence to nearest main road, the total length of main roads, traffic volume, and bus load within buffers of 50, 150, and 300m around each address. Cases were more likely to have any diesel buses passing within 50m of their home (adjusted odds ratios=1.16 and 1.10, 95% confidence intervals 1.041.30 and 1.011.20 for elective and emergency controls, respectively). Our findings indicated that older girls (514) and younger boys (04) had increased risks of respiratory hospitalization, albeit with generally widened confidence intervals due to small sample sizes. Our results add to the limited body of evidence regarding associations between diesel exhaust particles and respiratory morbidity. The findings also point to possible differential associations between traffic-related air pollution and pediatric hospitalization among boys and girls in different age groups.

Ronit Nirel; Michal Schiff; Ora Paltiel

2015-01-01T23:59:59.000Z

25

Workers Deliver Award-Winning Respiratory Safety | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Workers Deliver Award-Winning Respiratory Safety Workers Deliver Award-Winning Respiratory Safety Workers Deliver Award-Winning Respiratory Safety April 2, 2013 - 12:00pm Addthis Workers wear air purifying respirators in the Plutonium Finishing Plant. Workers wear air purifying respirators in the Plutonium Finishing Plant. A program developed by employees enhances use of respiratory equipment in the Plutonium Finishing Plant. A program developed by employees enhances use of respiratory equipment in the Plutonium Finishing Plant. Workers wear air purifying respirators in the Plutonium Finishing Plant. A program developed by employees enhances use of respiratory equipment in the Plutonium Finishing Plant. RICHLAND, Wash. - Workers supporting the Richland Operations Office at the Hanford site found a way to make their everyday work even safer.

26

Workers Deliver Award-Winning Respiratory Safety | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Deliver Award-Winning Respiratory Safety Deliver Award-Winning Respiratory Safety Workers Deliver Award-Winning Respiratory Safety April 2, 2013 - 12:00pm Addthis Workers wear air purifying respirators in the Plutonium Finishing Plant. Workers wear air purifying respirators in the Plutonium Finishing Plant. A program developed by employees enhances use of respiratory equipment in the Plutonium Finishing Plant. A program developed by employees enhances use of respiratory equipment in the Plutonium Finishing Plant. Workers wear air purifying respirators in the Plutonium Finishing Plant. A program developed by employees enhances use of respiratory equipment in the Plutonium Finishing Plant. RICHLAND, Wash. - Workers supporting the Richland Operations Office at the Hanford site found a way to make their everyday work even safer.

27

Simvastatin in the Acute Respiratory Distress Syndrome  

Science Journals Connector (OSTI)

...dysfunction and was safe. That phase 2 study was not designed or powered to show an effect of simvastatin on clinical outcomes. The aim of this trial was to test the hypothesis that treatment with enteral simvastatin at a dose of 80 mg daily would improve clinical outcomes in patients with ARDS, regardless of... In this study, patients with acute respiratory distress syndrome who were not receiving statins were assigned to receive simvastatin or placebo. At 28 days, there were no significant between-group differences in survival or in the number of ventilator-free days.

McAuley D.F.; Laffey J.G.; O'Kane C.M.

2014-10-30T23:59:59.000Z

28

Roadmap: Respiratory Therapy Technology Associate of Applied Science  

E-Print Network (OSTI)

Roadmap: Respiratory Therapy Technology ­ Associate of Applied Science [RE-AAS-RTT] Regional College Catalog Year: 2013-2014 Page 1 of 2 | Last Updated: 1-Apr-2013/LNHD This roadmap is a recommended Hours] Requirement: Admission into the Respiratory Therapy Technology program RTT 11000 Introduction

Sheridan, Scott

29

Roadmap: Respiratory Therapy Technology Associate of Applied Science  

E-Print Network (OSTI)

Roadmap: Respiratory Therapy Technology ­ Associate of Applied Science [RE-AAS-RTT] Regional College Catalog Year: 2012-2013 Page 1 of 2 | Last Updated: 16-Apr-12/LNHD This roadmap is a recommended Hours] Requirement: Admission into the Respiratory Therapy Technology program RTT 11000 Introduction

Sheridan, Scott

30

EFFECT OF NUTRITION ON THE RESPIRATORY VIRULENCE OF LISTERIA MONOCYTOGENES  

Science Journals Connector (OSTI)

...research-article Articles EFFECT OF NUTRITION ON THE RESPIRATORY...and Donald A. Kautter, Effect of nutrition on the respiratory...mice showed the same relation- ship, but in general were one-tenth the JHH values. The effects on strain A4413 in mice were...

Mischa E. Friedman; Donald A. Kautter

1962-03-01T23:59:59.000Z

31

Department of Environmental Health and Instructional Safety Respiratory Protection  

E-Print Network (OSTI)

. Seal Check. 5. Respiratory Fit Testing. 6. Inspection Procedures. 7. Cleaning and Storage Instructions. Introduction #12;Respiratory Protection Page 2 A respirator is used to remove specific air contaminants by passing ambient air through an air purifying element, filters, cartridges, or canisters. Training

de Lijser, Peter

32

E-Print Network 3.0 - acute respiratory bronchiolitis Sample...  

NLE Websites -- All DOE Office Websites (Extended Search)

steps to stay healthy... Summary: , respiratory syncytial virus (RSV), whooping cough and Severe Acute Respiratory Syndrome (SARS) are spread... influenza. and prevent the...

33

E-Print Network 3.0 - acute respiratory failure Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

Agricultural Research and Cooperative Extension Summary: not only to sneeze and cough but also to develop severe acute respiratory symptoms is more likely... in respiratory...

34

E-Print Network 3.0 - acute respiratory syndrome-associated Sample...  

NLE Websites -- All DOE Office Websites (Extended Search)

steps to stay healthy... Summary: , respiratory syncytial virus (RSV), whooping cough and Severe Acute Respiratory Syndrome (SARS) are spread... influenza. and prevent the...

35

E-Print Network 3.0 - acute respiratory syndrome Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

steps to stay healthy... Summary: , respiratory syncytial virus (RSV), whooping cough and Severe Acute Respiratory Syndrome (SARS) are spread... influenza. and prevent the...

36

E-Print Network 3.0 - acute bacterial respiratory Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

steps to stay healthy... Summary: , respiratory syncytial virus (RSV), whooping cough and Severe Acute Respiratory Syndrome (SARS) are spread... influenza. and prevent the...

37

E-Print Network 3.0 - acute viral respiratory Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

Get extra rest - viral infections take... , respiratory syncytial virus (RSV), whooping cough and Severe Acute Respiratory Syndrome (SARS) are spread... and others sick 12;Why...

38

E-Print Network 3.0 - alternative respiratory syndromes Sample...  

NLE Websites -- All DOE Office Websites (Extended Search)

steps to stay healthy... Summary: , respiratory syncytial virus (RSV), whooping cough and Severe Acute Respiratory Syndrome (SARS) are spread... influenza. and prevent the...

39

E-Print Network 3.0 - acute respiratory illness Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

Polytechnique, Centre de mathmatiques Collection: Mathematics 2 Why should I cover my cough? Serious respiratory illnesses like influenza, respiratory Summary: Why should I cover...

40

E-Print Network 3.0 - alternative respiratory pathway Sample...  

NLE Websites -- All DOE Office Websites (Extended Search)

3 Are pacemaker properties required for respiratory rhythm generation in adult turtle brain stems in vitro? Summary: Are pacemaker properties required for respiratory...

Note: This page contains sample records for the topic "respiratory disease orthopedic" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


41

E-Print Network 3.0 - associating respiratory health Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

Associate of Science - Respiratory Care Course... HLTHST 432 Critical Review of Health Care Research 3 RESPCARE 403 Respiratory Care Theory V 3 RESPCARE... Current Topics...

42

Natural Gas Stove Emissions and Respiratory Health: Evidence from NHANES  

NLE Websites -- All DOE Office Websites (Extended Search)

Natural Gas Stove Emissions and Respiratory Health: Evidence from NHANES Natural Gas Stove Emissions and Respiratory Health: Evidence from NHANES III Speaker(s): Ronald Briggs Date: August 15, 2007 - 12:00pm Location: 90-3122 Seminar Host/Point of Contact: Brett Singer Do emissions from natural gas stoves in American homes degrade respiratory health? The combustion of natural gas yields byproducts such as NOx , PM2.5 , and CO that the US EPA regulates outdoors. But while ambient air quality has improved in the US over the last few decades as a consequence of the Clean Air Act of and its amendments, the prevalence of asthma and morbidity and mortality associated with asthma continue to rise (Mannino /et al./, 1998). Concentrations of most air pollutants are higher indoors than outdoors in the US, however, and people in the US spend more than 90%

43

Nitric oxide and carbon monoxide in cigarette smoke in the development of cardiorespiratory disease in smokers  

E-Print Network (OSTI)

(Rep 1983). This could be due to indoor air pollution but respiratory disease in childhood may affect later respiratory function ( Burrows, Knudson and Lebvitz 1977). Similarly the decline in bronchitis mortality i n the U.K . in re c ent years which... anteceded the decline in cigarette cons umption might, in addition, suggest an effect of outdoor pollution Air Acts". The marked internat ional differences in mortality and the high figures for the British I sles...

Borland, Colin David Ross

1988-10-18T23:59:59.000Z

44

Air pollution, avoidance behaviour and children's respiratory health: Evidence from England  

Science Journals Connector (OSTI)

Abstract Despite progress in air pollution control, concerns remain over the health impact of poor air quality. Governments increasingly issue air quality information to enable vulnerable groups to avoid exposure. Avoidance behaviour potentially biases estimates of the health effects of air pollutants. But avoidance behaviour imposes a cost on individuals and therefore may not be taken in all circumstances. This paper exploits panel data at the English local authority level to estimate the relationship between children's daily hospital emergency admissions for respiratory diseases and common air pollutants, while allowing for avoidance behaviour in response to air pollution warnings. A 1% increase in nitrogen dioxide or ozone concentrations increases hospital admissions by 0.1%. For the subset of asthma admissions where avoidance is less costly there is evidence of avoidance behaviour. Ignoring avoidance behaviour, however, does not result in statistically significant underestimation of the health effect of air pollution.

Katharina Janke

2014-01-01T23:59:59.000Z

45

E-Print Network 3.0 - acidosis respiratory Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

respiratory Page: << < 1 2 3 4 5 > >> 1 Bio390 Acid -Base Disturbances thanks to Dr. J.F. Anderson, Summary: of respiratory acidosis or metabolic acidosis? What is the basis...

46

Human torso phantom for imaging of heart with realistic modes of cardiac and respiratory motion  

DOE Patents (OSTI)

A human torso phantom and its construction, wherein the phantom mimics respiratory and cardiac cycles in a human allowing acquisition of medical imaging data under conditions simulating patient cardiac and respiratory motion.

Boutchko, Rostyslav; Balakrishnan, Karthikayan; Gullberg, Grant T; O'Neil, James P

2013-09-17T23:59:59.000Z

47

Penn State Respiratory Protection Program Requirements Summary Scope and Application  

E-Print Network (OSTI)

operations, and during some non-routine or emergency operations such as a spill or leak of a hazardous respirators and evaluating hazards. · Select respiratory protection options. · Conduct fit testing. · Evaluate and do not cause discomfort. · Continually check work areas and operations to identify possible

Maroncelli, Mark

48

ORIGINAL PAPER Impacts of ocean acidification on respiratory gas exchange  

E-Print Network (OSTI)

ORIGINAL PAPER Impacts of ocean acidification on respiratory gas exchange and acid­base balance / Revised: 11 April 2012 / Accepted: 14 April 2012 ? Springer-Verlag 2012 Abstract The oceanic carbonate Gill HCO3 - uptake Introduction The earth's oceanic carbonate system (partial pressure of CO2, p

Grosell, Martin

49

Respiratory control in aquatic insects dictates their vulnerability to global warming  

Science Journals Connector (OSTI)

...their capacity to supply oxygen to tissues...respiratory control) is therefore...shifts in external temperatures typically drive...weaker respiratory control, they are likely...in mediating temperature effects, especially...upregulate oxygen supply under warmer...in respiratory control dictates the...

2013-01-01T23:59:59.000Z

50

Accuracy and Consistency of Respiratory Gating in Abdominal Cancer Patients  

SciTech Connect

Purpose: To evaluate respiratory gating accuracy and intrafractional consistency for abdominal cancer patients treated with respiratory gated treatment on a regular linear accelerator system. Methods and Materials: Twelve abdominal patients implanted with fiducials were treated with amplitude-based respiratory-gated radiation therapy. On the basis of daily orthogonal fluoroscopy, the operator readjusted the couch position and gating window such that the fiducial was within a setup margin (fiducial-planning target volume [f-PTV]) when RPM indicated beam-ON. Fifty-five pre- and post-treatment fluoroscopic movie pairs with synchronized respiratory gating signal were recorded. Fiducial motion traces were extracted from the fluoroscopic movies using a template matching algorithm and correlated with f-PTV by registering the digitally reconstructed radiographs with the fluoroscopic movies. Treatment was determined to be accurate if 50% of the fiducial area stayed within f-PTV while beam-ON. For movie pairs that lost gating accuracy, a MATLAB program was used to assess whether the gating window was optimized, the external-internal correlation (EIC) changed, or the patient moved between movies. A series of safety margins from 0.5 mm to 3 mm was added to f-PTV for reassessing gating accuracy. Results: A decrease in gating accuracy was observed in 44% of movie pairs from daily fluoroscopic movies of 12 abdominal patients. Three main causes for inaccurate gating were identified as change of global EIC over time (?43%), suboptimal gating setup (?37%), and imperfect EIC within movie (?13%). Conclusions: Inconsistent respiratory gating accuracy may occur within 1 treatment session even with a daily adjusted gating window. To improve or maintain gating accuracy during treatment, we suggest using at least a 2.5-mm safety margin to account for gating and setup uncertainties.

Ge, Jiajia; Santanam, Lakshmi; Yang, Deshan [Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri (United States)] [Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri (United States); Parikh, Parag J., E-mail: pparikh@radonc.wustl.edu [Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri (United States)

2013-03-01T23:59:59.000Z

51

E-Print Network 3.0 - apparent respiratory disease Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

de mathmatiques Collection: Mathematics 4 Bio390 Acid -Base Disturbances thanks to Dr. J.F. Anderson, Summary: .03 mmols L mmHg apparent pKa for carbonic acid-bicarbonate buffer...

52

Low Dose Radiation Research Program: Low Dose Response of Respiratory Cells  

NLE Websites -- All DOE Office Websites (Extended Search)

Response of Respiratory Cells in Intact Tissues and Reconstituted Response of Respiratory Cells in Intact Tissues and Reconstituted Tissue John Ford Department of Nuclear Engineering Texas A & M University Why this Project? Using the well-established rat trachea model to test the hypothesis that normal respiratory epithelial cells transmit signals to neighboring cells in response to very low dose radiation exposure. Project Goals By comparing the responses shown by cells in these normal rodent respiratory tissues to those seen for human respiratory epithelial cells in reconstituted tissue constructs, it will be possible to better understand the responds in human respiratory cells in vivo. These studies will characterize responses after exposure to a variety of radiation types and dose distributions. Experimental Approach

53

Medical Progress: How Contagious Are Common Respiratory Tract Infections?  

Science Journals Connector (OSTI)

...the 20th century. In general, the potential for an outbreak is modified by the general health and the level of specific immunity of the population at risk., Among South African miners in 1910 to 1912, the attack rate exceeded 1 percent per month, as it did in some military training camps during the... The answer to this frequently asked question is addressed in this review article, which focuses on common respiratory tract infections that are spread from person to person. The author concentrates on community-based contagion rather than nosocomial infections or agents that have received recent attention principally because of their actual or potential role in biologic terrorism.

Musher D.M.

2003-03-27T23:59:59.000Z

54

Transmission of the Severe Acute Respiratory Syndrome on Aircraft  

Science Journals Connector (OSTI)

...also be transmitted through airborne routes. Other potential modes of transmission include contact with contaminated fomites, contact resulting from the movement of the passengers closer together during the flight, and contact occurring in waiting areas or lines immediately before boarding or after disembarkation... This careful study is based on interviews of passengers and crew members on three flights that carried patients with the severe acute respiratory syndrome (SARS). Twenty-two persons became ill a mean of four days after one of the flights. The risk was highest among the passengers seated within three rows in front of the symptomatic index patient (relative risk, 3.1).

Olsen S.J.; Chang H.-L.; Cheung T.Y.-Y.

2003-12-18T23:59:59.000Z

55

E-Print Network 3.0 - assessing respiratory impairment Sample...  

NLE Websites -- All DOE Office Websites (Extended Search)

levels and make recommendations upon request. Respiratory... protection, employees must wear personal protective equipment. Hazard Assessment and Equipment Selection 2... .02...

56

E-Print Network 3.0 - aggravates respiratory syncytial Sample...  

NLE Websites -- All DOE Office Websites (Extended Search)

Tetrakis(dimethylamino)hafnium P-6280-B Date: February 2005 Copyright 2002, 2004-2005, Praxair Technology, Inc. Page 1 of 8 Summary: aggravate an existing dermatitis. Respiratory...

57

E-Print Network 3.0 - acute upper respiratory Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

Agricultural Research and Cooperative Extension Summary: not only to sneeze and cough but also to develop severe acute respiratory symptoms is more likely... of...

58

E-Print Network 3.0 - acute respiratory tract Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

Agricultural Research and Cooperative Extension Summary: not only to sneeze and cough but also to develop severe acute respiratory symptoms is more likely... Name Signs and...

59

Neurological Disease  

NLE Websites -- All DOE Office Websites (Extended Search)

Iron and neurodegenerative disease Iron and neurodegenerative disease A novel technique to study intracerebral iron oxide particles associated with Alzheimer's, Huntington's, and Parkinson's diseases has been developed. Researchers crafted a system of mirrors and lenses to tap one of the high-brightness x-ray sources at the Advanced Photon Source for the purpose of analyzing brain tissue. Mark Davidson (left in the photo), University of Florida, and Joanna Collingwood, Keele University in the United Kingdom (UK, who is supported by a UK Alzheimer's Society Research Fellowship and Dunhill Medical Trust), align a sample of Alzheimer's brain tissue at the microfocus facility, MR-CAT, beamline 10-ID. According to Davidson: "Unusual iron mineral nanoscale deposits have been associated with many neurodegenerative diseases, such as Alzheimer's,

60

Parkinson's Disease  

NLE Websites -- All DOE Office Websites (Extended Search)

Parkinson's Disease Parkinson's Disease Name: saabsaab Status: N/A Age: N/A Location: N/A Country: N/A Date: Around 1993 Question: I am interested in collecting information on Parkinson's Disease. Can you help me? Replies: Some possible sources include a neuroscience reference, a neurology text, a neurologist, neuroanatomy references. Basically Parkinson's disease is a movement disorder. It gets more and more difficult to move. One of the primary brain lesions associated with this disease is a shrinkage of an area in the brain stem called the substantia nigra. This is thought to be associated with the neurotransmitter dopamine and there seems to decreased production of the dopamine in this area. Some medications do seem to help including a dopamine replacement medicine called Sinemet. There are some new medicines coming out that may also help. Another exciting area is trying to get new dopamine cells to grow in the substantia nigra area, one way is to insert a needle into the area and inject immature nerve cells into the area and hope they will grow up to be mature dopamine producers, so far it is still considered somewhat experimental. The disease is thought to be caused by progressive cell loss. Some cases have been caused by people who synthesized drugs to abuse and they made a mistake and a bunch of young people took the drug and ended up with the disease. The silver lining of this is that this drug also will do the same thing in rats, so now there is an animal model for Parkinson's.

Note: This page contains sample records for the topic "respiratory disease orthopedic" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


61

Developmental basis of the rostro-caudal organization of the brainstem respiratory rhythm generator  

Science Journals Connector (OSTI)

...the respiratory rhythm generator (reviewed at post-natal...respiratory rhythm frequency: induction requires Krox20/Egr2...robustness of the dual rhythm generator in neonates, which...and hypocapnia in the induction of hyperpnoeic episodic...control of the rhythm generators by peripheral and central...

2009-01-01T23:59:59.000Z

62

ECG-Derived Respiration: Comparison and New Measures for Respiratory Variability  

E-Print Network (OSTI)

ECG-Derived Respiration: Comparison and New Measures for Respiratory Variability Devy Widjaja1 During ECG recording, several methods can be applied to derive a respiratory signal from the ECG (EDR signal). In this paper 4 EDR methods, including ECG filtering, R and RS amplitude based techniques

63

Accelerometer-Based method for extracting respiratory and cardiac gating information for dual gating during nuclear medicine imaging  

Science Journals Connector (OSTI)

Both respiratory and cardiac motions reduce the quality and consistency of medical imaging specifically in nuclear medicine imaging. Motion artifacts can be eliminated by gating the image acquisition based on the respiratory phase and cardiac contractions ...

Mojtaba Jafari Tadi, Tero Koivisto, Mikko Pnkl, Ari Paasio

2014-01-01T23:59:59.000Z

64

Whipple's Disease  

Science Journals Connector (OSTI)

...treatment currently is daily parenteral administration of streptomycin (1 g) and benzylpenicillin...hypopituitarism. . J. Caroli C. Julien B. Bonneville La maladie de Whipple. Revue generale...A. Huizenga D. C. Dahlin M. H. Power Whipples disease-report of four cases...

Florence Fenollar; Didier Raoult

2001-01-01T23:59:59.000Z

65

Wildlife Diseases  

E-Print Network (OSTI)

and avoid contact with wild rodents and rabbits. Rocky Mountain Spotted Fever Rocky Mountain Spotted Fever is a serious disease caused by the bacterium Rickettsia rick- ettsii. It can be transmitted to people by several species of ticks, including the lone...

Texas Wildlife Services

2007-03-13T23:59:59.000Z

66

Sorghum Diseases.  

E-Print Network (OSTI)

of organisms attacking seeds. Environmental conditions 1 encourage seed rot development also W~II increase the amount of damage caused by seedling disease. Vigorous seedlings produc:d from high-quality seed can withstand attack much better than low.... This fungus can cause considerable sorghum damage, although it usually is confined to individual fields or areas within fields that are occasionally flooded. Sorghum downy mildew, Sclerospora sorghi (Kulk) Weston & Uppal, was found first in Texas in 196...

Amador, Jose; Berry, Robert W.; Frederiksen, Richard A.; Horne, C. Wendell; Thames, Walter H.; Toler, Robert W.

1969-01-01T23:59:59.000Z

67

Dosimetry of internal exposure of respiratory tract to incorporated plutonium  

Science Journals Connector (OSTI)

ICRP Publication 66 that had adopted a new approach to estimate dose to lungs and an extrathoracic region based on a revised human respiratory tract model was considered by the authors to address some aspects related to application of ICRP 66 in radiation safety practices. Comparison of committed equivalent doses received to the lungs following acute inhalation of plutonium-239 aerosols with different solubility and particle size calculated as per previous ICRP 30 approach (averaging of energy imparted by radiation to the organ over the mass of the organ) and new ICRP 66 concept (detriment-weighted dose resulting from irradiation of specific cells at risk in the lung) showed that these dose estimates are disparate. At the same time, ICRP 66 approach, being more biologically reasonable, still requires additional studies to validate risk apportionment among tissues in the lungs. Because ICRP 66 for the first time introduced a method to calculate internal radiation dose to the extrathoracic region, equivalent dose to this region following acute inhalation of different plutonium-239 aerosols was assessed in comparison with equivalent dose to the lungs. The relative contribution of the extrathoracic region to the effective dose turned out to be significant.

S.A. Romanov; Y.V. Zaytseva

2006-01-01T23:59:59.000Z

68

Detection of Streptococcus pneumoniae in lower respiratory tract specimens by anaerobic culture technique.  

Science Journals Connector (OSTI)

...dard C02-enriched aerobic culture technique. These investi- gators suggest that the increased recovery of S. pneumoniae from respiratory...Laboratories) anaerobic system, whereas previous investi- gators used either a GasPak jar (BBL Microbiology Systems, Cockeysville...

R K Baesman; C L Strand

1984-04-01T23:59:59.000Z

69

John Widdicombes contribution to respiratory physiology and cough: reminiscences  

E-Print Network (OSTI)

But urge-to-cough is perplexing. I await confirmation orM, Widdicombe J: Fog-induced cough with impaired respiratoryJ: Desensitization of the cough reflex by exercise and

Chung, Kian Fan; Nadel, Jay A; Fontana, Giovanni

2013-01-01T23:59:59.000Z

70

Air pollution and respiratory health of school children in industrial, commercial and residential areas of Delhi  

Science Journals Connector (OSTI)

Air pollutants may cause severe respiratory problems in ... survey and lung function test. The outdoor air pollution data from the National Ambient Air Quality Monitoring (NAAQM) stations was used ... distance fr...

Jincy Mathew; Radha Goyal; K K Taneja; Naveen Arora

2014-10-01T23:59:59.000Z

71

Swimming pool attendance, respiratory symptoms and infections in the first year of life  

Science Journals Connector (OSTI)

We evaluated the relationship between indoor and outdoor swimming pool attendance and respiratory symptoms and infections during ... and 14months after birth. Information on swimming pool attendance and health m...

Laia Font-Ribera; Cristina M. Villanueva

2013-07-01T23:59:59.000Z

72

The Respiratory System and Diazotrophic Activity ofAcetobacter diazotrophicus PAL5  

Science Journals Connector (OSTI)

...and A extracted from submitochondrial particles from bovine heart, and photoheme IX obtained...Respiratory activities. Membrane particles of A. diazotrophicus grown in medium...his technical assistance and to Virginia God a nez for her secretarial assistance...

M. Flores-Encarnacin; M. Contreras-Zentella; L. Soto-Urzua; G. R. Aguilar; B. E. Baca; J. E. Escamilla

1999-11-01T23:59:59.000Z

73

Ammonia inhalation toxicity in cats: a study of acute and chronic respiratory dysfunction  

E-Print Network (OSTI)

AMMONIA INHALATION TOXICITY IN CATS A STUDY OF ACUTE AND CHRONIC RESPIRATORY DYSFUNCTION A Thesis by KENNETH TRAVIS DODD Submitted to the Graduate College of Texas A)M University in partial fulfillment of the requirement for the degree... of MASTER OF SCIENCE December 1978 Major Subject: Veterinary Physiology AMMONIA INHALATION TOXICITY IN CATS A STUDY OF ACUTE AND CHRONIC RESPIRATORY DYSFUNCTION A Thesis by KENNETH TRAVIS DODD Approved as to style and content by: (Chairman...

Dodd, Kenneth Travis

2012-06-07T23:59:59.000Z

74

Smoothing of respiratory motion traces for motion-compensated radiotherapy  

SciTech Connect

Purpose: The CyberKnife system has been used successfully for several years to radiosurgically treat tumors without the need for stereotactic fixation or sedation of the patient. It has been shown that tumor motion in the lung, liver, and pancreas can be tracked with acceptable accuracy and repeatability. However, highly precise targeting for tumors in the lower abdomen, especially for tumors which exhibit strong motion, remains problematic. Reasons for this are manifold, like the slow tracking system operating at 26.5 Hz, and using the signal from the tracking camera ''as is''. Since the motion recorded with the camera is used to compensate for system latency by prediction and the predicted signal is subsequently used to infer the tumor position from a correlation model based on x-ray imaging of gold fiducials around the tumor, camera noise directly influences the targeting accuracy. The goal of this work is to establish the suitability of a new smoothing method for respiratory motion traces used in motion-compensated radiotherapy. The authors endeavor to show that better prediction--With a lower rms error of the predicted signal--and/or smoother prediction is possible using this method. Methods: The authors evaluated six commercially available tracking systems (NDI Aurora, PolarisClassic, Polaris Vicra, MicronTracker2 H40, FP5000, and accuTrack compact). The authors first tracked markers both stationary and while in motion to establish the systems' noise characteristics. Then the authors applied a smoothing method based on the a trous wavelet decomposition to reduce the devices' noise level. Additionally, the smoothed signal of the moving target and a motion trace from actual human respiratory motion were subjected to prediction using the MULIN and the nLMS{sub 2} algorithms. Results: The authors established that the noise distribution for a static target is Gaussian and that when the probe is moved such as to mimic human respiration, it remains Gaussian with the exception of the FP5000 and the Aurora systems. The authors also showed that the proposed smoothing method can indeed be used to filter noise. The signal's jitter dropped by as much as 95% depending on the tracking system employed. Subsequently, the 3D prediction error (rms) for a prediction horizon of 150 ms on a synthetic signal dropped by up to 37% when using a normalized LMS prediction algorithm (nLMS{sub 2}) and hardly changed when using a MULIN algorithm. When smoothing a real signal obtained in our laboratory, the improvement of prediction was similar: Up to 30% for both the nLMS{sub 2} and the best MULIN algorithm. The authors also found a noticeable increase in smoothness of the predicted signal, the relative jitter dropped by up to 95% on the real signal, and on the simulated signal. Conclusions: In conclusion, the authors can say that preprocessing of marker data is very useful in motion-compensated radiotherapy since the quality of prediction increases. This will result in better performance of the correlation model. As a side effect, since the prediction of a preprocessed signal is also less noisy, the authors expect less robot vibration resulting in better targeting accuracy and less strain on the robot gears.

Ernst, Floris; Schlaefer, Alexander; Schweikard, Achim [Institute for Robotics and Cognitive Systems, University of Luebeck, Ratzeburger Allee 160, Luebeck SH 23538 (Germany)

2010-01-15T23:59:59.000Z

75

Respiratory triggered 4D cone-beam computed tomography: A novel method to reduce imaging dose  

SciTech Connect

Purpose: A novel method called respiratory triggered 4D cone-beam computed tomography (RT 4D CBCT) is described whereby imaging dose can be reduced without degrading image quality. RT 4D CBCT utilizes a respiratory signal to trigger projections such that only a single projection is assigned to a given respiratory bin for each breathing cycle. In contrast, commercial 4D CBCT does not actively use the respiratory signal to minimize image dose. Methods: To compare RT 4D CBCT with conventional 4D CBCT, 3600 CBCT projections of a thorax phantom were gathered and reconstructed to generate a ground truth CBCT dataset. Simulation pairs of conventional 4D CBCT acquisitions and RT 4D CBCT acquisitions were developed assuming a sinusoidal respiratory signal which governs the selection of projections from the pool of 3600 original projections. The RT 4D CBCT acquisition triggers a single projection when the respiratory signal enters a desired acquisition bin; the conventional acquisition does not use a respiratory trigger and projections are acquired at a constant frequency. Acquisition parameters studied were breathing period, acquisition time, and imager frequency. The performance of RT 4D CBCT using phase based and displacement based sorting was also studied. Image quality was quantified by calculating difference images of the test dataset from the ground truth dataset. Imaging dose was calculated by counting projections. Results: Using phase based sorting RT 4D CBCT results in 47% less imaging dose on average compared to conventional 4D CBCT. Image quality differences were less than 4% at worst. Using displacement based sorting RT 4D CBCT results in 57% less imaging dose on average, than conventional 4D CBCT methods; however, image quality was 26% worse with RT 4D CBCT. Conclusions: Simulation studies have shown that RT 4D CBCT reduces imaging dose while maintaining comparable image quality for phase based 4D CBCT; image quality is degraded for displacement based RT 4D CBCT in its current implementation.

Cooper, Benjamin J. [Radiation Physics Laboratory, Sydney Medical School, University of Sydney, NSW 2006, Australia and Department of Medical Physics and Radiation Engineering, Canberra Hospital, Canberra, ACT 2605 (Australia); O'Brien, Ricky T.; Keall, Paul J. [Radiation Physics Laboratory, Sydney Medical School, University of Sydney, NSW 2006 (Australia); Balik, Salim; Hugo, Geoffrey D. [Radiation Oncology, Virginia Commonwealth University, 401 College Street, P.O.Box 980058, Richmond, Virginia 23298-0058 (United States)

2013-04-15T23:59:59.000Z

76

Inhaled nitric oxide: another weapon in our armamentarium in the battle against acute hypoxic respiratory failure in preterm infants  

Science Journals Connector (OSTI)

Acute hypoxic respiratory failure (AHRF) remains a significant cause of death in intensive care units. With the realization that pathophysiologic abnormalities in AHRF involve surfactant abnormalities as well ...

Shonola S Da-Silva; R Phillip Dellinger

2004-02-01T23:59:59.000Z

77

Are you protected against Pertussis? Pertussis, or whooping cough, is a highly contagious respiratory infection caused by the bacterium  

E-Print Network (OSTI)

Are you protected against Pertussis? Pertussis, or whooping cough, is a highly contagious respiratory infection caused by the bacterium Bordetella pertussis. It causes severe coughing spells, vomiting

78

Knowledge and Misconceptions Regarding Upper Respiratory Infections and Influenza Among Urban Hispanic Households: Need for Targeted Messaging  

Science Journals Connector (OSTI)

Background To characterize knowledge and misconceptions regarding viral upper respiratory infections (URI) among urban Hispanics and identify correlates of greater knowledge. Methods...In-home in...

Elaine Larson; Yu-Hui Ferng; Jennifer Wong

2009-04-01T23:59:59.000Z

79

Low Dose Radiation Research Program: Low Dose Response of Respiratory Cells  

NLE Websites -- All DOE Office Websites (Extended Search)

Low Dose Radiation Research Program: Low Dose Response of Respiratory Low Dose Radiation Research Program: Low Dose Response of Respiratory Cells in Intact Tissues and Reconstituted Tissue Constructs Authors: John Ford, Amy Maslowski, Alex Redd and Les Braby Institutions: Texas A&M University, College Station, TX We are developing a model of respiratory tissue using a perfusion culture system. We are using this system to quantify the effects of normal tissue architecture, and the interaction of epithelial cells with other cell types, on radiation-induced bystander effects. Tracheal tissue taken from young adult Fischer 344 rats is imbedded in a growth factor enriched agarose matrix. The chamber is designed to allow growth medium to periodically wash the epithelial surface of the tracheal lumen while maintaining the air-interface that is necessary for the normal

80

Ehrlichia Infection as a Cause of Severe Respiratory Distress  

Science Journals Connector (OSTI)

...State Department of Health recently alerted physicians about human granulocytic ehrlichiosis in Westchester County, in the lower Hudson River valley, and on Long Island. This region has a high incidence of Lyme disease associated with the Ixodes scapularis tick vector. It has a high population density... To the Editor: Human ehrlichiosis is increasingly being recognized as a cause of a diverse spectrum of illness in geographic regions where the tick vectors are found. The New York State Department of Health recently alerted physicians about human ...

1996-01-25T23:59:59.000Z

Note: This page contains sample records for the topic "respiratory disease orthopedic" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


81

Modulation of respiratory pumping behavior in the marine opisthobranch Aplysia californica  

E-Print Network (OSTI)

of MASTER OF SCIENCE August 1993 Major Subject: Biology MODULATION OF RESPIRATORY PUMPING IN THE MARINE OPISTHOBRANCH +P Y~A QAAIF~RNI A A Thesis NATALIE BANNEEL Approved as to style and content by: ames E. Ka (Co-Chair of Committee) Merrill H. eet... 31 34 37 44 57 62 136 FIGURE LIST OF FIGURES Page Schematic of ~ showing structures involved in respiratory pumping. . 9 Diagram of the abdominal ganglion showing the associated parts of the circultory system and the peripheral nerves...

Banneel, Natalie

2012-06-07T23:59:59.000Z

82

Leptin and the control of respiratory gene expression in muscle G.B. McClellanda,1  

E-Print Network (OSTI)

, D. Michauda , J.C. Russellb , C.R. Muellerc , C.D. Moyesa,* a Department of Biology, Queen involved in mitochondrial biogenesis (nuclear respiratory factor-1 (NRF-1), nuclear respiratory factor-2 (NRF-2)) or fatty acid enzyme expression (peroxisome proliferator-activated receptors (PPARs

Hawai'i at Manoa, University of

83

Clinical performance evaluation of Sofia RSV FIA rapid antigen test for the diagnosis of respiratory syncytial virus infection  

Science Journals Connector (OSTI)

...Clinical performance evaluation of Sofia RSV FIA rapid antigen test for the diagnosis of respiratory syncytial virus infection Jin...comparatively with the BinaxNow RSV Card and the SD Bioline RSV test using 348 respiratory samples. The Sofia, BinaxNow and SD Bioline...

Jin Woo Jang; Chi Hyun Cho; Myung-Hyun Nam; Soo Young Yoon; Chang Kyu Lee; Chae Seung Lim; Woo Joo Kim

2014-11-26T23:59:59.000Z

84

CFD simulations of enhanced condensational growth (ECG) applied to respiratory drug delivery with comparisons to in vitro data  

E-Print Network (OSTI)

CFD simulations of enhanced condensational growth (ECG) applied to respiratory drug delivery t Enhanced condensational growth (ECG) is a newly proposed concept for respiratory drug delivery in which and evaluate a CFD model of ECG in a simple tubular geometry with direct comparisons to in vitro results

Frey, Pascal

85

Geologic occurrences of erionite in the United States: an emerging national public health concern for respiratory disease  

Science Journals Connector (OSTI)

Prior to 2005, the erionite occurrence in the United States that drew the most interest as a potential health hazard was at Yucca Mountain, Nevada. This occurrence of erionite in...1989; Bish and Chipera 1991...)...

Bradley S. Van Gosen; Thomas A. Blitz

2013-08-01T23:59:59.000Z

86

Characterization of Bioaerosols from Dairy Barns: Reconstructing the Puzzle of Occupational Respiratory Diseases by Using Molecular Approaches  

Science Journals Connector (OSTI)

...the Coriolis (Bertin Technologies, Montigny-le-Bretonneux...908-917. 7. Bertin Technologies. Coriolis brochure. Bertin Technologies, Montigny-le-Bretonneux...fileadmin/publication/Intranet/WikiConseil/Machinisme...

Pascale Blais Lecours; Marc Veillette; David Marsolais; Caroline Duchaine

2012-02-24T23:59:59.000Z

87

Respiratory patterns reflect different levels of aggressiveness and emotionality in Wild-type Groningen rats  

Science Journals Connector (OSTI)

Abstract Respiratory patterns represent a promising physiological index for assessing emotional states in preclinical studies. Since disturbed emotional regulation may lead to forms of excessive aggressiveness, in this study we investigated the hypothesis that rats that differ largely in their level of aggressive behavior display matching alterations in respiration. Respiration was recorded in male high-aggressive (HA, n=8) and non-aggressive (NA, n=8) Wild-type Groningen rats using whole-body plethysmography. Subsequently, anxiety-related behaviors were evaluated in the elevated plus maze and social avoidanceapproach tests. During respiratory testing, HA rats showed elevated basal respiratory rate, reduced sniffing, exaggerated tachypnoeic response to an acoustic stimulus and a larger incidence of sighs. In addition, HA rats spent less time in the open arms of the plus maze and displayed higher levels of social avoidance behavior compared to NA rats. These findings indicate that HA rats are characterized by alterations in respiratory functioning and behavior that are overall indicative of an anxiety-like phenotype.

Luca Carnevali; Eugene Nalivaiko; Andrea Sgoifo

2014-01-01T23:59:59.000Z

88

Prevalence of respiratory symptoms and cases suspicious for tuberculosis among public health clinic patients in Afghanistan,  

E-Print Network (OSTI)

, and diagnostic test results were recorded. Correlates of TB-suggestive symptoms (defined as cough >2 weeks children (age 17 or under). The TB-suggestive symptoms of cough >2 weeks and / or haemoptysis were reported workers. keywords Afghanistan, tuberculosis, respiratory symptoms, cough, sputum smear accuracy

Scharfstein, Daniel

89

initial rise in respiratory quotient (RQ) was also similar in both groups. However, in rats  

E-Print Network (OSTI)

initial rise in respiratory quotient (RQ) was also similar in both groups. However, in rats fed in rats fed the TC diet the decline in RQ was more progressive and began its decrease only 3-4 h after ad libitum to two groups of eight male Wister rats. Rats fed the TD diet showed the first significant

Paris-Sud XI, Université de

90

A realistic coupled nonlinear artificial ECG, BP and respiratory signal generator for assessing noise performance  

E-Print Network (OSTI)

A realistic coupled nonlinear artificial ECG, BP and respiratory signal generator for assessing differential equations is capable of generating realistic synthetic electrocardiograms (ECGs). Open source code with realistic inter-signal coupling between the respiration, BP and ECG time series. The time-varying surface

McSharry, Patrick E.

91

An examination of interventions to reduce respiratory health and injury hazards in homes of low-income families  

SciTech Connect

We evaluated whether combining asthma trigger reduction with housing structural repairs, device disbursement and education in low-income households with children would improve self-reported respiratory health and reduce housing-related respiratory health and injury hazards (convenience sample of n=67 homes with 63 asthmatic and 121 non-asthmatic children). At baseline, a visual assessment of the home environment and a structured occupant interview were used to examine 29 potential injury hazards and 7 potential respiratory health hazards. A home-specific intervention was designed to provide the children's parents or caretakers with the knowledge, skills, motivation, supplies, equipment, and minimum housing conditions necessary for a healthy and safe home. The enrolled households were primarily Hispanic and owned their homes. On average, 8 injury hazards were observed in the homes at baseline. Four months following intervention, the average declined to 2.2 hazards per home (p<0.001), with 97% of the parents reporting that their homes were safer following the interventions. An average of 3.3 respiratory health hazards were observed in the homes at baseline. Four months following intervention, the average declined to 0.9 hazards per home (p<0.001), with 96% of parents reporting that the respiratory health of their asthmatic children improved. A tailored healthy homes improvement package significantly improves self-reported respiratory health and safety, reduces respiratory health and injury hazards, and can be implemented in concert with a mobile clinical setting.

Dixon, Sherry L. [National Center for Healthy Housing, 10320 Little Patuxent Parkway, Suite 500, Columbia, MD 21044 (United States)], E-mail: sdixon@nchh.org; Fowler, Cecile [City of Phoenix, Neighborhood Services Department, Phoenix, AZ (United States); Harris, Judy; Moffat, Sally [Phoenix Children's Hospital, Phoenix, AZ (United States); Martinez, Yolanda [City of Phoenix, Neighborhood Services Department, Phoenix, AZ (United States); Walton, Heather; Ruiz, Bernice [Phoenix Children's Hospital, Phoenix, AZ (United States); Jacobs, David E. [National Center for Healthy Housing, 10320 Little Patuxent Parkway, Suite 500, Columbia, MD 21044 (United States)

2009-01-15T23:59:59.000Z

92

Interim Chronic Beryllium Disease  

Directives, Delegations, and Requirements

Establishes Departmental expectations for addressing chronic beryllium disease throughout the Department until a Departmental rule on beryllium is promulgated. This Notice was replaced by final rule 10 CFR Part 850, Chronic Beryllium Disease Prevention Program, published December 8, 1999.

1999-12-08T23:59:59.000Z

93

Global Health: Disease Eradication  

Science Journals Connector (OSTI)

...have been considered as potential candidates for eradication, but the World Health Organization (WHO) has targeted only two other diseases for global eradication after smallpox. In 1986, WHO's policymaking body, the World Health Assembly, adopted the elimination of dracunculiasis (guinea worm disease)... The most cost-effective intervention for certain infectious diseases is to eliminate them entirely. This article reviews the characteristics of potentially eradicable diseases and surveys current eradication methods.

Hopkins D.R.

2013-01-03T23:59:59.000Z

94

A cross-sectional study of secondhand smoke exposure and respiratory symptoms in non-current smokers in the U.S. trucking industry: SHS exposure and respiratory symptoms  

E-Print Network (OSTI)

with chronic phlegm, chronic cough, and any wheeze, defined= 1.00- 2.13) for chronic cough, 1.55 (95% CI = 1.08-2.21)respiratory symptoms, including cough, phlegm and wheeze, in

Laden, Francine; Chiu, Yueh-Hsiu; Garshick, Eric; Hammond, S; Hart, Jaime E

2013-01-01T23:59:59.000Z

95

International Dose-Response Society and Lovelace Respiratory Research Insitue present a Webinar  

NLE Websites -- All DOE Office Websites (Extended Search)

Lovelace Respiratory Research Institute Lovelace Respiratory Research Institute and Present a Webinar Radiation Hormesis and Life - Mild Radiation Stress Makes You Stronger May 25, 2010 at 12:00 p.m. (MST), 6:00 p.m. (GMT) Presenter: Bobby R. Scott, PhD, LRRI Senior Scientist 2425 Ridgecrest Drive SE, Albuquerque, NM 87108 USA E-mail: bscott@LRRI.org Register for the webinar using this e-mail address: registration@LRRI.org. Please provide your name, the number of attendees, and your organizational affiliation in the message. Registration is free, but the num- ber of attendees is limited, so please register as soon as possible. After registering, you will receive further instructions for logging onto the website. Questions may be sent

96

In utero and early life arsenic exposure in relation to long-term health and disease  

SciTech Connect

Background: There is a growing body of evidence that prenatal and early childhood exposure to arsenic from drinking water can have serious long-term health implications. Objectives: Our goal was to understand the potential long-term health and disease risks associated with in utero and early life exposure to arsenic, as well as to examine parallels between findings from epidemiological studies with those from experimental animal models. Methods: We examined the current literature and identified relevant studies through PubMed by using combinations of the search terms arsenic, in utero, transplacental, prenatal and fetal. Discussion: Ecological studies have indicated associations between in utero and/or early life exposure to arsenic at high levels and increases in mortality from cancer, cardiovascular disease and respiratory disease. Additional data from epidemiologic studies suggest intermediate effects in early life that are related to risk of these and other outcomes in adulthood. Experimental animal studies largely support studies in humans, with strong evidence of transplacental carcinogenesis, atherosclerosis and respiratory disease, as well as insight into potential underlying mechanisms of arsenic's health effects. Conclusions: As millions worldwide are exposed to arsenic and evidence continues to support a role for in utero arsenic exposure in the development of a range of later life diseases, there is a need for more prospective studies examining arsenic's relation to early indicators of disease and at lower exposure levels. - Highlights: We review in utero and early-life As exposure impacts on lifelong disease risks. Evidence indicates that early-life As increases risks of lung disease, cancer and CVD. Animal work largely parallels human studies and may lead to new research directions. Prospective studies and individual exposure assessments with biomarkers are needed. Assessing intermediary endpoints may aid early intervention and establish causality.

Farzan, Shohreh F.; Karagas, Margaret R. [Children's Environmental Health and Disease Prevention Research Center at Dartmouth, Hanover, NH 03755 (United States); Section of Biostatistics and Epidemiology, Department of Community and Family Medicine and Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth, Lebanon, NH 03756 (United States); Chen, Yu, E-mail: yu.chen@nyumc.org [Department of Population Health, New York University School of Medicine, New York, NY 10016 (United States)

2013-10-15T23:59:59.000Z

97

Chronic effects of ambient air pollution on respiratory morbidities among Chinese children: a cross-sectional study in Hong Kong  

Science Journals Connector (OSTI)

The chronic health effects from exposure to ambient air pollution are still unclear. This study primarily aims ... the relationship between long-term exposure to ambient air pollution and respiratory morbidities ...

Yang Gao; Emily YY Chan; Liping Li; Patrick WC Lau; Tze Wai Wong

2014-02-01T23:59:59.000Z

98

cbb3-Type Cytochrome c Oxidases, Aerobic Respiratory Enzymes, Impact the Anaerobic Life of Pseudomonas aeruginosa PAO1  

Science Journals Connector (OSTI)

...on the role of respiratory enzymes in energy conservation; however, their effect...Respiration is a fundamental process for energy conservation. In eukaryotic mitochondria...oxidases have been reported to catalyze energy conservation; however, few studies have...

Masakaze Hamada; Masanori Toyofuku; Tomoki Miyano; Nobuhiko Nomura

2014-09-02T23:59:59.000Z

99

Correlation of gross tumor volume excursion with potential benefits of respiratory gating  

SciTech Connect

Purpose: To test the hypothesis that the magnitude of thoracic tumor motion can be used to determine the desirability of respiratory gating. Methods and materials: Twenty patients to be treated for lung tumors had computed tomography image data sets acquired under assisted breath hold at normal inspiration (100% tidal volume), at full expiration (0% tidal volume), and under free breathing. A radiation oncologist outlined gross tumor volumes (GTVs) on the breath-hold computed tomographic images. These data sets were registered to the free-breathing image data set. Two sets of treatment plans were generated: one based on an internal target volume explicitly formed from assessment of the excursion of the clinical target volume (CTV) through the respiratory cycle, representing an ungated treatment, and the other based on the 0% tidal volume CTV, representing a gated treatment with little margin for residual motion. Dose-volume statistics were correlated to the magnitude of the motion of the center of the GTV during respiration. Results: Patients whose GTVs were >100 cm{sup 3} showed little decrease in lung dose under gating. The other patients showed a correlation between the excursion of the center of the GTV and a reduction in potential lung toxicity. As residual motion increased, the benefits of respiratory gating increased. Conclusion: Gating seems to be advantageous for patients whose GTVs are <100 cm{sup 3} and for whom the center of the GTV exhibits significant motion, provided residual motion under gating is kept small.

Starkschall, George [Department of Radiation Physics, University of Texas M.D. Anderson Cancer Center, Houston, TX (United States)]. E-mail: gstarksc@mdanderson.org; Forster, Kenneth M. [Department of Radiation Physics, University of Texas M.D. Anderson Cancer Center, Houston, TX (United States); Kitamura, Kei [Department of Radiation Physics, University of Texas M.D. Anderson Cancer Center, Houston, TX (United States); Department of Radiology, Hokkaido University, Graduate School of Medicine, Sapporo (Japan); Cardenas, Alex [Department of Radiation Physics, University of Texas M.D. Anderson Cancer Center, Houston, TX (United States); Tucker, Susan L. [Department of Biomathematics, University of Texas M.D. Anderson Cancer Center, Houston, TX (United States); Stevens, Craig W. [Department of Radiation Oncology, University of Texas M.D. Anderson Cancer Center, Houston, TX (United States)

2004-11-15T23:59:59.000Z

100

Orthopedic Correction of Growing Retrognathic Hyperdivergent Patients  

E-Print Network (OSTI)

appliance. Two maxillary and two mandibular MSIs (immediately loaded with 150gr coil springs) were used for the intrusion mechanics and vertical control. A matched control group was used to evaluate the skeletal changes that occurred during treatment. CBCT...

Carrillo, Roberto

2014-05-13T23:59:59.000Z

Note: This page contains sample records for the topic "respiratory disease orthopedic" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


101

Host Plants and Their Diseases  

Science Journals Connector (OSTI)

The information telescoped into this section is taken in large part from the records of the Plant Disease Survey as given in the Plant Disease Reporter, Plant Diseases and from the Index of Plant Diseases in the ...

R. Kenneth Horst Ph.D.

2001-01-01T23:59:59.000Z

102

Host Plants and Their Diseases  

Science Journals Connector (OSTI)

The information telescoped in this section is taken in large part from the records of the Plant Disease Survey as given in the Plant Disease Reporter, Plant Diseases, and the Index of Plant Diseases in the United...

R. Kenneth Horst Ph.D.

1990-01-01T23:59:59.000Z

103

Biological Agents and Infectious Diseases in War and Terrorism  

Science Journals Connector (OSTI)

War and the preparation for war cause serious damage to human health and the environment. Several biologic agents can be weaponized, but biologic weapons have been rarely used during war or in terrorist attacks. Of much greater concern is the increased occurrence of infectious diseases during war and its aftermath due to damage to medical care and public health facilities and the health-supporting infrastructure, forced migration of refugees and internally displaced persons, and diversion of human and financial resources. Although biologic weapons have almost never been used effectively in war and terrorism, they represent a potential threat. Biologic weapons are difficult to develop, access, and use in warfare or terrorist attacks. Nevertheless, it is important for health professionals and others to have an awareness of these potential weapons and what can be done to control them and prevent their use. Infectious diseases frequently increase in occurrence or severity during war and its aftermath. These include diarrheal diseases, acute respiratory infections, measles, malaria, meningococcal disease, and tuberculosis. Health professionals and others can play important roles in addressing these issues, by working to minimize the adverse consequences of war and terrorism and by helping to create a world without war and terrorism.

B.S. Levy; V.W. Sidel

2011-01-01T23:59:59.000Z

104

Radiology of thoracic diseases  

SciTech Connect

This book presents the essential clinical and radiologic findings of a wide variety of thoracic diseases. The authors include conventional, CT and MR images of each disease discussed. In addition, they present practical differential diagnostic considerations for most of the radiographic findings or patterns portrayed.

Swensen, S.J.; Pugatch, R.D.

1989-01-01T23:59:59.000Z

105

The Dutch Elm Disease  

NLE Websites -- All DOE Office Websites (Extended Search)

Dutch Elm Disease Dutch Elm Disease Nature Bulletin No. 411-A March 20, 1971 Forest Preserve District of Cook County George W. Dunne, President Roland F. Eisenbeis, Supt. of Conservation THE DUTCH ELM DISEASE The American elm, far and away our most popular and important shade tree, is facing its most threatening enemy, the Dutch Elm Disease. A large part of them seem to be doomed unless up-to-date methods of control are used. In New England the appearance of whole towns has been changed by the loss of gigantic elms along entire streets. This same havoc is being repeated in most eastern states and, now, as far west as Missouri. The first diseased tree in Illinois was found downstate fifteen years ago. Since then, the infection has spread over most of the state, reaching the Chicago region in 1954.

106

Adventures in Infectious Diseases  

SciTech Connect

Dr. Susan Fisher-Hoch, Virologist and Epidemiologist, will discuss her research and travels associated with viral hemorrhagic fevers. From the Ebola outbreak in Reston, Virginia to outbreaks of Crimean Congo Hemorrhagic Fever in South Africa, Senegal, and Saudi Arabia, Dr. Fisher-Hoch has studied and tracked the pathophysiology of these viral diseases. These studies have led her from the Center for Disease Control in the United States, to Lyon, France where she was instrumental in designing, constructing, and rendering operational a laboratory capable of containing some of the world's most dangerous diseases.

Fisher-Hoch, Susan [University of Texas School of Public Health

2011-11-01T23:59:59.000Z

107

Drug Therapy: Alzheimer's Disease  

Science Journals Connector (OSTI)

...provide evidence supporting the concept that vitamin E, as well as vitamin C, has a role in delaying the onset of Alzheimer's disease. Memantine. Memantine, an N-methyl-D-aspartate antagonist recently approved by the Food and Drug Administration (FDA) for the treatment of moderate-to-severe Alzheimer's... The prevalence of Alzheimer's disease is predicted to reach 13.2 million cases in the United States. This article considers current therapeutic approaches for Alzheimer's disease. Optimal management requires accurate diagnosis, which is increasingly based on an understanding of pathophysiology. Neuroprotective strategies, cholinesterase inhibitors, psychopharmacologic agents that may reduce behavioral disturbances, and newer agents such as memantine are discussed.

Cummings J.L.

2004-07-01T23:59:59.000Z

108

Nanomedicine and Cardiovascular Disease  

Science Journals Connector (OSTI)

Nanomedicine has become an important tool in the ... respect to cardiovascular disease and its sequelae, nanomedicine has the potential to detect and treat ... the most poignant examples of the utility of nanomedicine

Jason R. McCarthy

2010-02-01T23:59:59.000Z

109

Neuropathology of Salla disease  

Science Journals Connector (OSTI)

A neuropathological study was performed on two patients with Salla disease, one male and one female, from different families. They both died at the age of 41 years. Both patients showed increased excretion of ...

H. Autio-Harmainen; A. Oldfors; P. Sourander; M. Renlund

1988-01-01T23:59:59.000Z

110

Inside Alzheimer's Disease  

NLE Websites -- All DOE Office Websites (Extended Search)

with illnesses ranging from cholera to vascular disease see the August 2011 and August 2014 issues of 1663, respectively. To that list, he and his Los Alamos colleague Ann...

111

Evaluation of a Ventilation Strategy to Prevent Barotrauma in Patients at High Risk for Acute Respiratory Distress Syndrome  

Science Journals Connector (OSTI)

...site classified the primary cause of deaths in the intensive care units as respiratory failure (due to profound hypoxemia), multiple-organ failure (three or more organs), sepsis, cardiac arrhythmia, or withdrawal of life support from a patient because of an irreversible chronic condition. Secondary outcomes... A strategy of mechanical ventilation that places limits on airway pressure and tidal volume has been recommended for patients with the acute respiratory distress syndrome.14 This recommendation is based on the observation that mechanical ventilation, ...

Stewart T.E.; Meade M.O.; Cook D.J.

1998-02-05T23:59:59.000Z

112

DOE-STD-1167-2003; Respiratory Acceptance Program for Supplied-Air Suits  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

NOT MEASUREMENT SENSITIVE DOE-STD-1167-2003 OCTOBER 2003 DOE STANDARD THE DEPARTMENT OF ENERGY RESPIRATORY ACCEPTANCE PROGRAM FOR SUPPLIED-AIR SUITS U.S. Department of Energy AREA SAFT Washington, D.C. 20585 DISTRIBUTION STATEMENT A. Approved for public release; distribution is unlimited. This document has been reproduced directly from the best available copy. Available to DOE and DOE contractors from ES&H Technical Information Services, U.S. Department of Energy, (800) 473-4375, fax: (301) 903-9823. Available to the public from the U.S. Department of Commerce, Technology Administration, National Technical Information Service, Springfield, VA 22161; (703) 605-6000. ii DOE-STD-1167-2003 FOREWORD This non-mandatory Technical Standard provides the Department of Energy (DOE) and contractor

113

Pneumonia and Respiratory Failure from Swine-Origin Influenza A (H1N1) in Mexico  

Science Journals Connector (OSTI)

...molecular features of North American and Eurasian swine, avian, and human influenza viruses was found. In the same month, the World Health Organization (WHO) classified the global spread of this virus as a public health event of international concern. After documentation of human-to-human transmission... This case series describes the first 18 patients hospitalized with infection with novel swine-origin influenza A (H1N1) virus (S-OIV) from March 24 through April 24, 2009, in Mexico City. More than half the patients were between 13 and 47 years of age, and most had been healthy previously. Respiratory distress requiring intubation and mechanical ventilation developed in 10 patients; 7 patients died. There were 22 secondary infections among health care workers, none of which required hospitalization.

Perez-Padilla R.; de la Rosa-Zamboni D.; Ponce de Leon S.

2009-08-13T23:59:59.000Z

114

Evidence of Airborne Transmission of the Severe Acute Respiratory Syndrome Virus  

Science Journals Connector (OSTI)

...rates through doorways and windows (closed and open) were assumed to be dependent on differences in air pressure. Differences in air temperature and winds, as well as the exhaust from fans, could introduce driving pressures. We used the software program MIX, which was developed by Li et al. to model the... This analysis used detailed airflow-dynamics studies to model the possible airborne spread of the virus in the large outbreak of the severe acute respiratory syndrome (SARS) in the Amoy Gardens housing complex in Hong Kong. The spatial distribution of the cases supports the hypothesis that a single index patient was the source of infection and the infection was spread by virus-laden aerosols.

Yu I.T.S.; Li Y.; Wong T.W.

2004-04-22T23:59:59.000Z

115

Effect of xenobiotics on the respiratory activity of rat heart mitochondria and the concomitant formation of superoxide radicals  

SciTech Connect

The effects of the xenobiotics atrazine, benzene, butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), lindane, toluene, and xylenol on the respiration of isolated rate heart mitochondria were studied. Bioenergetic parameters such as respiratory control (RC) and ATP/oxygen (P/O) values decreased considerably in the presence of these substances, and a concomitant increase of superoxide radical (O[sub 2][sup [minus

Stolze, K.; Nohl, H. (Univ. of Vienna (Austria). Inst. of Pharmacology and Toxicology)

1994-03-01T23:59:59.000Z

116

Four-dimensional image-based treatment planning: Target volume segmentation and dose calculation in the presence of respiratory motion  

SciTech Connect

Purpose: To describe approaches to four-dimensional (4D) treatment planning, including acquisition of 4D-CT scans, target delineation of spatio-temporal image data sets, 4D dose calculations, and their analysis. Methods and Materials: The study included patients with thoracic and hepatocellular tumors. Specialized tools were developed to facilitate visualization, segmentation, and analysis of 4D-CT data: maximum intensity volume to define the extent of lung tumor motion, a 4D browser to examine and dynamically assess the 4D data sets, dose calculations, including respiratory motion, and deformable registration to combine the dose distributions at different points. Results: Four-dimensional CT was used to visualize and quantitatively assess respiratory target motion. The gross target volume contours derived from light breathing scans showed significant differences compared with those extracted from 4D-CT. Evaluation of deformable registration using difference images of original and deformed anatomic maps suggested the algorithm is functionally useful. Thus, calculation of effective dose distributions, including respiratory motion, was implemented. Conclusion: Tools and methods to use 4D-CT data for treatment planning in the presence of respiratory motion have been developed and applied to several case studies. The process of 4D-CT-based treatment planning has been implemented, and technical barriers for its routine use have been identified.

Rietzel, Eike [Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (United States) and Abteilung Biophysik, Gesellschaft fuer Schwerionenforschung, Darmstadt (Germany)]. E-mail: eike@rietzel.net; Chen, George T.Y. [Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (United States); Choi, Noah C. [Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (United States); Willet, Christopher G. [Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (United States)

2005-04-01T23:59:59.000Z

117

Generating 24-Hour ECG, BP and Respiratory Signals with Realistic Linear and Nonlinear Clinical Characteristics Using a Nonlinear Model  

E-Print Network (OSTI)

Generating 24-Hour ECG, BP and Respiratory Signals with Realistic Linear and Nonlinear Clinical, London School of Economics, London, UK Abstract A nonlinear model for generating lifelike human ECG it to three ordinary differential equations, the model generates a 24-hour ECG signal. Using both standard

McSharry, Patrick E.

118

A linear, time-varying simulation of the respiratory tract system  

SciTech Connect

These results show that regional deposition efficiencies of inhaled particles are highly dependent on the level of physical activity in all the spectrum of thermodynamic and aerodynamic aerosol particle sizes; also it was shown that for particles in the aerodynamic size range, the values of regional deposition efficiencies at the inner regions of the lung are highly dependent on age. In addition, the shape of regional deposition efficiency curves as a function of particle size have a similar behavior for all ages; thus, any variation of the airway geometry and respiratory physiological parameters such as tidal volumes and breathing frequencies due to age difference do not cause a change in the fundamental mechanisms of deposition. Thus, for all the cases of physical activity and age dependency, the deposition of ultrafine aerosol particles is highly enhanced by diffusive processes in all regions of the respiratory tract, and for very large aerosol size particles this behavior is repeated again due to impaction and sedimentation mechanisms. Although the results presented at this work, are the result of computer simulations based on different sources of experimental data, the structure of the computer simulation code BIODEP is flexible enough to the acquisition of any kind of new experimental information in terms of biokinetic analysis and regional deposition parameters. In addition, since the design of BIODEP was intended for easy access to the users, then with exception of the subroutine DIVPAG, at this moment, the modular design of BIODEP using FORTRAN 77 allows the implementation of all the subroutines of BIODEP to be used in a interactive mode with any microcomputer.

Hernandez, O.

1992-11-01T23:59:59.000Z

119

Periodontal Disease and Heart Health  

E-Print Network (OSTI)

Periodontal Disease and Heart Health Deaf HealthTalks Presenter: Christopher Lehfeldt, DDS Elmwood #12;X-ray showing bone loss rickwilsondmd.typepad.com Thursday, March 15, 12 #12;5. What is heart disease? · The medical name for heart disease is cardiovascular disease (CVD) · An American dies from CVD

Goldman, Steven A.

120

Handbook of Cerebrovascular Diseases  

Science Journals Connector (OSTI)

...medical education. There is a lot to keep up with. Thus, this major textbook focused on cerebrovascular diseases is timely. The second edition of Handbook of Cerebrovascular Diseases is a revised and expanded version of the first edition, published in 1994. It is a standard multiauthored book, but the... Stroke is hot right now. Even physicians who do not specialize in vascular neurology the subspecialty that has just recently gained formal recognition recognize that after decades of medicine's having very little to offer, therapeutic advances for ...

Mayer S.A.

2006-04-06T23:59:59.000Z

Note: This page contains sample records for the topic "respiratory disease orthopedic" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


121

Health & Medicine Heart Disease  

E-Print Network (OSTI)

See Also: Health & Medicine Heart Disease· Medical Imaging· Vioxx· Matter & Energy Electronics· Technology· Medical Technology· Reference Artificial heart· Biosensor· Circuit design· Machine· Science and stretchable electronics can map waves of electrical activity in the heart with better resolution and speed

Rogers, John A.

122

Dynamic volume vs respiratory correlated 4DCT for motion assessment in radiation therapy simulation  

SciTech Connect

Purpose: Conventional (i.e., respiratory-correlated) 4DCT exploits the repetitive nature of breathing to provide an estimate of motion; however, it has limitations due to binning artifacts and irregular breathing in actual patient breathing patterns. The aim of this work was to evaluate the accuracy and image quality of a dynamic volume, CT approach (4D{sub vol}) using a 320-slice CT scanner to minimize these limitations, wherein entire image volumes are acquired dynamically without couch movement. This will be compared to the conventional respiratory-correlated 4DCT approach (RCCT). Methods: 4D{sub vol} CT was performed and characterized on an in-house, programmable respiratory motion phantom containing multiple geometric and morphological ''tumor'' objects over a range of regular and irregular patient breathing traces obtained from 3D fluoroscopy and compared to RCCT. The accuracy of volumetric capture and breathing displacement were evaluated and compared with the ground truth values and with the results reported using RCCT. A motion model was investigated to validate the number of motion samples needed to obtain accurate motion probability density functions (PDF). The impact of 4D image quality on this accuracy was then investigated. Dose measurements using volumetric and conventional scan techniques were also performed and compared. Results: Both conventional and dynamic volume 4DCT methods were capable of estimating the programmed displacement of sinusoidal motion, but patient breathing is known to not be regular, and obvious differences were seen for realistic, irregular motion. The mean RCCT amplitude error averaged at 4 mm (max. 7.8 mm) whereas the 4D{sub vol} CT error stayed below 0.5 mm. Similarly, the average absolute volume error was lower with 4D{sub vol} CT. Under irregular breathing, the 4D{sub vol} CT method provides a close description of the motion PDF (cross-correlation 0.99) and is able to track each object, whereas the RCCT method results in a significantly different PDF from the ground truth, especially for smaller tumors (cross-correlation ranging between 0.04 and 0.69). For the protocols studied, the dose measurements were higher in the 4D{sub vol} CT method (40%), but it was shown that significant mAs reductions can be achieved by a factor of 4-5 while maintaining image quality and accuracy. Conclusions: 4D{sub vol} CT using a scanner with a large cone-angle is a promising alternative for improving the accuracy with which respiration-induced motion can be characterized, particularly for patients with irregular breathing motion. This approach also generates 4DCT image data with a reduced total scan time compared to a RCCT scan, without the need for image binning or external respiration signals within the 16 cm scan length. Scan dose can be made comparable to RCCT by optimization of the scan parameters. In addition, it provides the possibility of measuring breathing motion for more than one breathing cycle to assess stability and obtain a more accurate motion PDF, which is currently not feasible with the conventional RCCT approach.

Coolens, Catherine; Bracken, John; Driscoll, Brandon; Hope, Andrew; Jaffray, David [Radiation Medicine Program, Princess Margaret Hospital, Toronto, Ontario M5G 2M9, Canada and Department of Radiation Oncology, University of Toronto, Toronto, Ontario M5S 3S2 (Canada); Radiation Medicine Program, Princess Margaret Hospital, Toronto, Ontario M5G 2M9 (Canada); Radiation Medicine Program, Princess Margaret Hospital, Toronto, Ontario M5G 2M9, Canada and Department of Radiation Oncology, University of Toronto, Toronto, Ontario M5S 3S2 (Canada); Radiation Medicine Program, Princess Margaret Hospital, Toronto, Ontario M5G 2M9 (Canada); Department of Radiation Oncology, University of Toronto, Toronto, Ontario M5S 3S2 (Canada) and Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 2M9 (Canada)

2012-05-15T23:59:59.000Z

123

Integrating respiratory gating into a megavoltage cone-beam CT system  

SciTech Connect

We have previously described a low-dose megavoltage cone beam computed tomography (MV CBCT) system capable of producing projection image using one beam pulse. In this study, we report on its integration with respiratory gating for gated radiotherapy. The respiratory gating system tracks a reflective marker on the patient's abdomen midway between the xiphoid and umbilicus, and disables radiation delivery when the marker position is outside predefined thresholds. We investigate two strategies for acquiring gated scans. In the continuous rotation-gated acquisition, the linear accelerator (LINAC) is set to the fixed x-ray mode and the gantry makes a 5 min, 360 deg.continuous rotation, during which the gating system turns the radiation beam on and off, resulting in projection images with an uneven distribution of projection angles (e.g., in 70 arcs each covering 2 deg.). In the gated rotation-continuous acquisition, the LINAC is set to the dynamic arc mode, which suspends the gantry rotation when the gating system inhibits the beam, leading to a slightly longer (6-7 min) scan time, but yielding projection images with more evenly distributed projection angles (e.g., {approx}0.8 deg.between two consecutive projection angles). We have tested both data acquisition schemes on stationary (a contrast detail and a thoracic) phantoms and protocol lung patients. For stationary phantoms, a separate motion phantom not visible in the images is used to trigger the RPM system. Frame rate is adjusted so that approximately 450 images (13 MU) are acquired for each scan and three-dimensional tomographic images reconstructed using a Feldkamp filtered backprojection algorithm. The gated rotation-continuous acquisition yield reconstructions free of breathing artifacts. The tumor in parenchymal lung and normal tissues are easily discernible and the boundary between the diaphragm and the lung sharply defined. Contrast-to-noise ratio (CNR) is not degraded relative to nongated scans of stationary phantoms. The continuous rotation-gated acquisition scan also yields tomographic images with discernible anatomic features; however, streak artifacts are observed and CNR is reduced by approximately a factor of 4. In conclusion, we have successfully developed a gated MV CBCT system to verify the patient positioning for gated radiotherapy.

Chang Jenghwa; Sillanpaa, Jussi; Ling, Clifton C.; Seppi, Edward; Yorke, Ellen; Mageras, Gikas; Amols, Howard [Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York 10021 (United States); Ginzton Technology Center, Varian Medical Systems, Mountain View, California 94043 (United States); Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York 10021 (United States)

2006-07-15T23:59:59.000Z

124

Soybean Diseases Atlas.  

E-Print Network (OSTI)

of the upper stern. In severe cases, the stem may have large lesions and numerous secondary roots may develop on the stem above the soil line. ... Lightning Injury Lightning sometimes Injures soybeans in the field. Lightning injury looks like a circular... are a clue to lightning damage. Since lightning damage can be mistaken for disease or insect injury, a careful examination of the field should be made before lightning in jury is diagnosed . ? ? Metribuzin (Sencor or Lexone) Injury Metribuzin...

Anonymous,

1979-01-01T23:59:59.000Z

125

Case 17-2005 A 22-Year-Old Woman with Back and Leg Pain and Respiratory Failure  

Science Journals Connector (OSTI)

...this woman was, a single therapy is rarely enough for stabilization. Combinations of the therapies listed above can have additive effects. A flow chart shows an incremental approach to a patient with catastrophic ARDS, which we followed in this case (Figure 2). The final measure is the use of extracorporeal... A 22-year-old woman was transferred because of respiratory failure. She had a history of sickle cell anemia and had back and leg pain the day before she was admitted to another hospital, where respiratory failure developed while she was being treated for a sickle cell crisis. After transfer, assisted ventilation, nitric oxide, and exchange transfusion did not reverse the hypoxemia, and the patient died. An autopsy was performed.

Medoff B.D.Shepard J.-A.O.Smith R.N.Kratz A.

2005-06-09T23:59:59.000Z

126

Coal home heating and environmental tobacco smoke in relation to lower respiratory illness in Czech children, from birth to 3 years of age  

E-Print Network (OSTI)

Young SA, et al. 1993. Nitrogen dioxide and respiratory ill-as nitric oxide and nitrogen dioxide would occur only inLRI from exposures to nitrogen dioxide (Samet et al. 1993).

2006-01-01T23:59:59.000Z

127

Management of Respiratory Motion in Extracorporeal High-Intensity Focused Ultrasound Treatment in Upper Abdominal Organs: Current Status and Perspectives  

SciTech Connect

Extracorporeal high-intensity focused ultrasound (HIFU) is a minimally invasive therapy considered with increased interest for the ablation of small tumors in deeply located organs while sparing surrounding critical tissues. A multitude of preclinical and clinical studies have showed the feasibility of the method; however, concurrently they showed several obstacles, among which the management of respiratory motion of abdominal organs is at the forefront. The aim of this review is to describe the different methods that have been proposed for managing respiratory motion and to identify their advantages and weaknesses. First, we specify the characteristics of respiratory motion for the liver, kidneys, and pancreas and the problems it causes during HIFU planning, treatment, and monitoring. Second, we make an inventory of the preclinical and clinical approaches used to overcome the problem of organ motion. Third, we analyze their respective benefits and drawbacks to identify the remaining physical, technological, and clinical challenges. We thereby consider the outlook of motion compensation techniques and those that would be the most suitable for clinical use, particularly under magnetic resonance thermometry monitoring.

Muller, A., E-mail: arnaud.muller@chu-lyon.fr [Centre Hospitalier Lyon Sud, Service de Radiologie, Hospices Civils de Lyon (France); Petrusca, L.; Auboiroux, V. [University of Geneva, Department of Radiology, Faculty of Medicine (Switzerland)] [University of Geneva, Department of Radiology, Faculty of Medicine (Switzerland); Valette, P. J. [Centre Hospitalier Lyon Sud, Service de Radiologie, Hospices Civils de Lyon (France)] [Centre Hospitalier Lyon Sud, Service de Radiologie, Hospices Civils de Lyon (France); Salomir, R. [University of Geneva, Department of Radiology, Faculty of Medicine (Switzerland)] [University of Geneva, Department of Radiology, Faculty of Medicine (Switzerland); Cotton, F. [Centre Hospitalier Lyon Sud, Service de Radiologie, Hospices Civils de Lyon (France)] [Centre Hospitalier Lyon Sud, Service de Radiologie, Hospices Civils de Lyon (France)

2013-12-15T23:59:59.000Z

128

Maximum-Intensity Volumes for Fast Contouring of Lung Tumors Including Respiratory Motion in 4DCT Planning  

SciTech Connect

Purpose: To assess the accuracy of maximum-intensity volumes (MIV) for fast contouring of lung tumors including respiratory motion. Methods and Materials: Four-dimensional computed tomography (4DCT) data of 10 patients were acquired. Maximum-intensity volumes were constructed by assigning the maximum Hounsfield unit in all CT volumes per geometric voxel to a new, synthetic volume. Gross tumor volumes (GTVs) were contoured on all CT volumes, and their union was constructed. The GTV with all its respiratory motion was contoured on the MIV as well. Union GTVs and GTVs including motion were compared visually. Furthermore, planning target volumes (PTVs) were constructed for the union of GTVs and the GTV on MIV. These PTVs were compared by centroid position, volume, geometric extent, and surface distance. Results: Visual comparison of GTVs demonstrated failure of the MIV technique for 5 of 10 patients. For adequate GTV{sub MIV}s, differences between PTVs were <1.0 mm in centroid position, 5% in volume, {+-}5 mm in geometric extent, and {+-}0.5 {+-} 2.0 mm in surface distance. These values represent the uncertainties for successful MIV contouring. Conclusion: Maximum-intensity volumes are a good first estimate for target volume definition including respiratory motion. However, it seems mandatory to validate each individual MIV by overlaying it on a movie loop displaying the 4DCT data and editing it for possible inadequate coverage of GTVs on additional 4DCT motion states.

Rietzel, Eike [Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (United States); Abteilung Biophysik, Gesellschaft fuer Schwerionenforschung, Darmstadt (Germany)], E-mail: eike@rietzel.net; Liu, Arthur K.; Chen, George T.Y.; Choi, Noah C. [Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (United States)

2008-07-15T23:59:59.000Z

129

Nitrogen dioxide and respiratory illness in children. Part II: Assessment of exposure to nitrogen dioxide  

SciTech Connect

Repeated measurements of nitrogen dioxide were obtained from 1988 to 1991 in the homes of 1,205 infants living in Albuquerque, NM. Passive diffusion samplers were used to obtain a series of two-week integrated measurements from the home of each infant for use in a cohort study of the relation of residential exposure to nitrogen dioxide and respiratory illnesses. Information on stove use and time spent inside the residence was collected at two-week and two-month intervals, respectively. During the winter, in the bedrooms of homes with gas cooking stoves, mean nitrogen dioxide concentrations were 21 parts per billion (ppb); mean concentrations in the living room and kitchen were 29 ppb and 34 ppb, respectively. In homes with electric cooking stoves, the mean bedroom concentration was 7 ppb during the winter. Lower indoor concentrations were observed during the summer in homes with both gas and electric stoves. On average, infants spent approximately 12.3 hours per day in their bedrooms, 7.3 hours in the living rooms, 35 minutes in the kitchens, and 3.8 hours out of their homes. (As a condition of participation, none of the infants spent more than 20 hours per week in day care outside of their homes). The mean time infants spent in the kitchen during cooking was approximately nine minutes per day. We tested whether exposures of infants living in homes with gas stoves could be reasonably estimated by measurements in the bedroom in comparison with time-weighted average concentrations based on time-activity data and simultaneous nitrogen dioxide measurements in the kitchen, living room, and bedroom. In 1,937 two-week intervals from 587 infants, 90% of time-weighted exposure (on the three-level classification used in this study) estimates were in agreement with estimates based on bedroom concentrations alone.

Lambert, W.E.; Samet, J.M.; Hunt, W.C.; Skipper, B.J.; Schwab, M.; Spengler, J.D. (Univ. of New Mexico Medical Center, Albuquerque (United States))

1993-06-01T23:59:59.000Z

130

Respiratory Motion of The Heart and Positional Reproducibility Under Active Breathing Control  

SciTech Connect

Purpose: To reduce cardiotoxicity from breast radiotherapy (RT), innovative techniques are under investigation. Information about cardiac motion with respiration and positional reproducibility under active breathing control (ABC) is necessary to evaluate these techniques. Methods and Materials: Patients requiring loco-regional RT for breast cancer were scanned by computed tomography using an ABC device at various breath-hold states, before and during treatment. Ten patients were studied. For each patient, 12 datasets were analyzed. Mutual information-based regional rigid alignment was used to determine the magnitude and reproducibility of cardiac motion as a function of breathing state. For each scan session, motion was quantified by evaluating the displacement of a point along the left anterior descending artery (LAD) with respect to its position at end expiration. Long-term positional reproducibility was also assessed. Results: Displacement of the LAD was greatest in the inferior direction, moderate in the anterior direction, and lowest in the left-right direction. At shallow breathing states, the average displacement of LAD position was up to 6 mm in the inferior direction. The maximum displacement in any patient was 2.8 cm in the inferior direction, between expiration and deep-inspiration breath hold. At end expiration, the long-term reproducibility (SD) of the LAD position was 3 mm in the A-P, 6 mm in the S-I, and 4 mm in the L-R directions. At deep-inspiration breath hold, long-term reproducibility was 3 mm in the A-P, 7 mm in the S-I, and 3 mm in the L-R directions. Conclusions: These data demonstrate the extent of LAD displacement that occurs with shallow breathing and with deep-inspiration breath hold. This information may guide optimization studies considering the effects of respiratory motion and reproducibility of cardiac position on cardiac dose, both with and without ABC.

Jagsi, Reshma [Department of Radiation Oncology, University of Michigan, Ann Arbor, MI (United States); Moran, Jean M. [Department of Radiation Oncology, University of Michigan, Ann Arbor, MI (United States); Kessler, Marc L. [Department of Radiation Oncology, University of Michigan, Ann Arbor, MI (United States); Marsh, Robin B. C [Department of Radiation Oncology, University of Michigan, Ann Arbor, MI (United States); Balter, James M. [Department of Radiation Oncology, University of Michigan, Ann Arbor, MI (United States); Pierce, Lori J. [Department of Radiation Oncology, University of Michigan, Ann Arbor, MI (United States)]. E-mail: ljpierce@umich.edu

2007-05-01T23:59:59.000Z

131

Novel Class of Benzoic Acid Ester Derivatives as Potent PDE4 Inhibitors for Inhaled Administration in the Treatment of Respiratory Diseases  

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A series of novel ester derivatives of 1-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-(3,5-dichloropyridin-4-yl) ethanol have been synthesized and evaluated for inhibitory activity toward cAMP-specific phosphodiesterase-4 (PDE4). ... Intratracheal administration of compound 32a was performed by placing the micronized drug blended with lactose into a dry powder insufflator (Penn Century, Philadelphia, PA, USA). ...

Elisabetta Armani; Gabriele Amari; Andrea Rizzi; Renato De Fanti; Eleonora Ghidini; Carmelida Capaldi; Laura Carzaniga; Paola Caruso; Matilde Guala; Ilaria Peretto; Elena La Porta; Pier T. Bolzoni; Fabrizio Facchinetti; Chiara Carnini; Nadia Moretto; Riccardo Patacchini; Franco Bassani; Valentina Cenacchi; Roberta Volta; Francesco Amadei; Silvia Capacchi; Maurizio Delcanale; Paola Puccini; Silvia Catinella; Maurizio Civelli; Gino Villetti

2014-01-08T23:59:59.000Z

132

The CREST Biorepository: A Tool for Molecular Epidemiology and Translational Studies on Malignant Mesothelioma, Lung Cancer, and Other Respiratory Tract Diseases  

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...or paramedical personnel of the clinical...networked alarm system operating 24 hours a day...Standardization. A standard operating procedure manual...distribution, and staff training and internal audits...of resources and personnel is required. Unfortunately...studies; (b) the selection of a homogenous...

Ugolini Donatella; Neri Monica; Canessa Pier Aldo; Casilli Cristina; Catrambone Giuseppe; Ivaldi Giovanni Paolo; Lando Cecilia; Marroni Paola; Paganuzzi Michela; Parodi Barbara; Visconti Paola; Puntoni Riccardo; and Bonassi Stefano

2008-11-01T23:59:59.000Z

133

Increased Biofilm Formation by Nontypeable Haemophilus influenzae Isolates from Patients with Invasive Disease or Otitis Media versus Strains Recovered from Cases of Respiratory Infections  

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...to a solid surface by the BioFilm ring test and quantified biofilm formation by crystal...absorbance from at least three independent tests and comparing it with the absorbance of...adhesion was evaluated by the BioFilm ring test (Biofilm Control, St Beauzire, France...

Carmen Puig; Arnau Domenech; Junkal Garmendia; Jeroen D. Langereis; Pascal Mayer; Laura Calatayud; Josefina Liares; Carmen Ardanuy; Sara Marti

2014-09-05T23:59:59.000Z

134

Interfractional Reproducibility of Lung Tumor Location Using Various Methods of Respiratory Motion Mitigation  

SciTech Connect

Purpose: To determine interfractional reproducibility of the location of lung tumors using respiratory motion mitigation. Methods and Materials: Free-breathing four-dimensional computed tomography (CT) data sets and CT data sets during breath hold were acquired weekly for 17 patients undergoing treatment for non-small-cell lung cancer. Distances between the center of the gross tumor volume (GTV) and a reproducible bony reference point under conditions of breath hold on end inspiration (EI) and end expiration (EE) and during free breathing on the 0% phase (corresponding to EI) and 50% phase (corresponding to EE) were analyzed for interfractional reproducibility. Systematic uncertainties in tumor location were determined as the difference in distance between the GTV center on the first CT data set and the mean location of GTV centers on the subsequent data sets. Random uncertainties in tumor location were determined as the standard deviation of the distances between the GTV centers and the bony reference points. Margins to account for systematic and random interfractional variations were estimated based on these uncertainties. Results: Mean values of interfractional setup uncertainties were as follows: systematic uncertainties-EI, 0.3 cm; EE, 0.2 cm; 0% phase, 0.3 cm; and 50% phase, 0.3 cm; and random uncertainties-EI, 0.3 cm; EE, 0.3 cm; 0% phase, 0.3 cm; and 50% phase, 0.3 cm. There does not appear to be any correlation between uncertainties and GTV size, but there appears to be a weak positive correlation between uncertainties and the magnitude of GTV excursion. Conclusions: Voluntary breath hold and gating on either EI or EE appear to be equally reliable methods of ensuring the reproducibility of lung tumor position. We recommend setup margins of 0.3 cm if using cone-beam CT or kilovoltage X-ray with fiducials and aligning directly to the tumor and 0.8 cm when aligning to a nearby bony surrogate using cone-beam CT or kilovoltage X-ray.

Starkschall, George, E-mail: gstarksc@mdanderson.or [Department of Radiation Physics, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Balter, Peter [Department of Radiation Physics, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Britton, Keith [Department of Radiation Physics, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); McAleer, Mary F.; Cox, James D. [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Mohan, Radhe [Department of Radiation Physics, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States)

2011-02-01T23:59:59.000Z

135

Case 9-2013 A 9-Year-Old Boy with Fever, Cough, Respiratory Distress, and Chest Pain  

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...strongly suspected that the patient's exposure was in his home. During the patient's hospitalization, investigation of the residence by state officials and a company specializing in indoor-mold remediation revealed that there was a malfunction of the venting system in the basement, with visible mold. The... A 9-year-old boy was admitted to the hospital because of fever, cough, respiratory distress, and chest pain. Imaging revealed ill-defined nodular opacities throughout all lung lobes, areas of consolidation, and mediastinal and hilar lymphadenopathy.

Fracchia M.S.El Saleeby C.M.Murali M.R.Sagar P.Mino-Kenudson M.

2013-03-21T23:59:59.000Z

136

Foot-and-Mouth Disease  

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...Greenport, New York 11944 Foot-and-mouth disease (FMD...AGENT The recent outbreaks of foot-and-mouth disease (FMD...vesicular lesions on the tongue, feet, snout, and teats (see Pathogenesis...production, and loss of draught power, resulting in a loss in productivity...

Marvin J. Grubman; Barry Baxt

2004-04-01T23:59:59.000Z

137

The ethics of disease eradication  

Science Journals Connector (OSTI)

Abstract This paper provides an examination of the ethics of disease eradication policies. It examines three arguments that have been advanced for thinking that eradication is in some way ethically exceptional as a policy goal. These are (1) global eradication has symbolic importance, (2) disease eradication is a global public good and (3) disease eradication is a form of rescue. It argues that none of these provides a good reason to think that individuals have special duties to facilitate eradication campaigns, or that public health authorities have special permissions to pursue them. But the fact that these arguments fail does not entail that global disease eradication is ethically problematic, or that it should not be undertaken. Global eradication of a disease, if successful, is a way of providing an enormous health benefit that stretches far into the future. There is no need to reach for the idea that there is a special duty to eradicate disease; the same considerations that are in play in ordinary public health policy of reducing the burden of disease equitably and efficiently suffice to make global disease eradication a compelling goal where doing so is feasible.

James Wilson

2014-01-01T23:59:59.000Z

138

Occupational Disease in Connecticut, 2011  

E-Print Network (OSTI)

1 Occupational Disease in Connecticut, 2011 This report covers data for 2009 and was prepared under contract for the State of Connecticut Workers' Compensation Commission, John A. Mastropietro, Chairman, as part of the Occupational Disease Surveillance Program, operated in cooperation with the Connecticut

Oliver, Douglas L.

139

Occupational Disease in Connecticut, 2014  

E-Print Network (OSTI)

Occupational Disease in Connecticut, 2014 This report covers data for 2012 and was prepared under contract for the State of Connecticut Workers' Compensation Commission, John A. Mastropietro, Chairman, as part of the Occupational Disease Surveillance Program, operated in cooperation with the Connecticut

Oliver, Douglas L.

140

Turfgrass Disease Profiles Brown Patch  

E-Print Network (OSTI)

Turfgrass Disease Profiles Brown Patch Richard Latin, Professor of Plant Pathology Brown patch to algae and moss infestation. Even mild brown patch outbreaks can spoil the appearance of golf greens and perennial ryegrass) also may sustain damage from brown patch infection. Disease Characteristics and Symptom

Note: This page contains sample records for the topic "respiratory disease orthopedic" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


141

Air pollutant monitoring for the East Bay Children's Respiratory Health Study  

SciTech Connect

This report describes the methodology and presents the summary results of the air pollutant monitoring program conducted by Lawrence Berkeley National Laboratory in support of the East Bay Children's Respiratory Health Study. The full study is examining the effects of chronic exposure to traffic-related pollutants on respiratory health among 3rd and 4th grade children attending ten neighborhood elementary schools in the San Francisco East Bay Area (Hayward, San Leandro and Oakland, CA). The demographically similar schools are located at varying distances from the I-880 and CA-92 freeways. Several schools were selected because they are located within 300 m in the predominant downwind direction (east) from either of the freeways. Measurements of multiple pollutants were made outdoors at the schools over 1-2 week intervals for 14 weeks in spring and eight weeks in fall 2001 using a custom-designed and validated package of commercially available monitoring equipment. Particulate matter was sampled over all hours (24 h per day) or during schools hours only with battery-operated programmable pumps and inlet devices for PM{sub 10} and PM{sub 2.5}. These pumps were modified to allow for up to 10 days of continuous operation. Fine particle mass and black carbon (BC) were determined from the collected filters. Nitrogen oxides (NO{sub x} and NO{sub 2}) were measured with passive samplers. Carbon monoxide (CO) was measured continuously with an electrochemical sensor. Gasoline-related volatile organic compounds (VOCs) were measured with passive samplers during three 4-week intervals in spring 2001 and two 4-week periods in early 2002. All samplers were deployed in a metal cabinet located outside at each school. Ranges of study average pollutant concentrations (all-hours) at the ten individual schools were: NO{sub x}, 33-68 ppb; NO{sub 2}, 19-31 ppb; PM{sub 10} mass, 27-32 {micro}g/m{sup 3}; PM{sub 2.5} mass, 12-15 {micro}g/m{sup 3}; and BC associated with PM{sub 2.5}, 0.6-1.0 {micro}g/m{sup 3}. Although statistical analysis of the data is yet to be performed, some general observations can be made. Absolute pollutant levels varied by season and week, but the simultaneous sampling design allowed for comparisons of concentrations among schools during each interval. Pollutant concentrations at each school were normalized to the sampling period averages among all schools. The normalized concentrations were generally consistent at each school throughout the entire study, suggesting that measured differences represent ongoing conditions and chronic exposures in the vicinities of the schools. Substantially elevated concentrations of NO{sub x}, NO{sub 2}, and BC, and somewhat elevated concentrations of PM{sub 2.5} were observed at one school located less than 100 meters to the east of I-880. Normalized concentrations of NO{sub x}, NO{sub 2}, and BC were also higher at the three other ''nearby and downwind'' schools relative to those located far from any freeway or other major traffic source. An ancillary monitoring program was implemented to examine the correlation between school-based pollutant measurements and measurements throughout the neighborhoods adjacent to three of the schools. Volunteer households were obtained from among the families of participating schoolchildren. Concentrations of NO{sub x} and NO{sub 2} were measured with passive samplers outside the homes of these volunteers during one of two 1-week periods in spring 2002. Simultaneous measurements were conducted at all ten of the schools and a central monitoring station during each week. The neighborhoods surrounding two schools were predominantly upwind of the I-880 freeway, while the neighborhood surrounding the other school was downwind from I-880. The overall distribution of concentrations observed for the residences near the downwind school appeared to be substantially higher than the regional background concentrations. The variability observed within the neighborhoods appeared to be, at least in part, explained by the proximity of individual residences to the freeway or

Singer, Brett C.; Hotchi, Toshifumi; Hodgson, Alfred T.

2002-11-01T23:59:59.000Z

142

Polyphenols, Inflammation, and Cardiovascular Disease  

Science Journals Connector (OSTI)

Polyphenols are compounds found in foods such as tea, coffee, cocoa, olive oil, and red wine and have been studied to determine if their intake may modify cardiovascular disease (CVD) risk. Historically, biolo...

Christy C. Tangney; Heather E. Rasmussen

2013-03-01T23:59:59.000Z

143

Nanomedical Theranostics in Cardiovascular Disease  

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Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide. New diagnostic and therapeutic strategies are needed to mitigate this public health issue. Advances in nanotechnology have g...

Jun Tang; Mark E. Lobatto; Joanna C. Read

2012-02-01T23:59:59.000Z

144

Blackberry Diseases and Their Control.  

E-Print Network (OSTI)

-plant soil fumigant to^ reduce nematode populations to acceptable levels. 2 . Anthracnsse, sometimes called dieback, is a common foliage and cane disease of blackberries and is first noticeable in the spring on new shoots and a s purple- bordered... common in your area. 2. Examine roots before planting to ensure ab- sence of crown gall. 3. Do not propagate cuttings from diseased plants. 4. Choose planting sites with good air circulation. 5. Destroy all wild berry plants and brambles inl nearby...

Philley, George L.; Smith, Leon R.

1982-01-01T23:59:59.000Z

145

Diarrheal Disease in Show Swine  

E-Print Network (OSTI)

are not important as a human disease. Cryptosporidium spp protozoa can rarely cause inap- parent infection or mild diarrhea in swine. Swine are not an important source for cryptosporidiosis in humans. Giardia spp protozoal infection in swine is rare, but it does... of gain. Lawsonia intracellularis is the causative bacterium. Though it is rarely the cause of diarrheal disease in show swine, veterinarians consider this organism as a potential cause when making a differ- ential diagnosis. L. intracellularis does...

Lawhorn, D. Bruce

2007-02-27T23:59:59.000Z

146

E-Print Network 3.0 - atherothrombotic cardiovascular disease...  

NLE Websites -- All DOE Office Websites (Extended Search)

disease, the number one killer of all Americans. Cardiovascular disease, or heart disease is the primary cause Summary: Kidney disease is both a cause and a consequence...

147

Interrelationship of dietary vitamin B12 or fat with thyrotoxicosis in certain adaptive changes in respiratory enzymes of rat liver  

E-Print Network (OSTI)

OF DIETARY VITAMIN B12 OR FAT WITH THYROTOXICOSIS IN CERTAIN ADAPTIVE CHANGES IN RESPIRATORY ENZYMES OF RAT LIVER (Head of Department) May, 1957 ACKNOWLEDGEMENTS Sincere gratitude is expressed to Dr. H. 0. Kunkel for his guidance and helpful suggestions...R 6OAp aR6T4TRH4FpAgFLSASiT4SETE EACaTREu ^WTLEA RicRLTZRHAkn l: Yju 1CZZOLF S6 R66R4AE S6 ?TAOZTH P q aR6T4TRH4F OHa AgFLSASiT4SETE CcSH LOA 5T?RL RHJFZR O4AT?TAF ^WTLEA RicRLTZRHAk ? ;pppppppppppppppppppppppppppppppppppppppppppppppppppppp ql ju...

Crawford, Wid Philips

2013-10-04T23:59:59.000Z

148

Respiratory Failure Due to Differentiation Arrest and Expansion of Alveolar Cells following Lung-Specific Loss of the Transcription Factor C/EBP? in Mice  

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...481-492. 42 Oh, H. S., and R. C. Smart. 1998. Expression of CCAAT/enhancer...S. J. Ewing, S. Zhu, and R. C. Smart. 2005. Diminished expression of C...EBPalpha pathway might have therapeutic benefits for patients with respiratory distress...

Daniela S. Bassres; Elena Levantini; Hongbin Ji; Stefano Monti; Shannon Elf; Tajhal Dayaram; Maris Fenyus; Olivier Kocher; Todd Golub; Kwok-kin Wong; Balazs Halmos; Daniel G. Tenen

2006-02-01T23:59:59.000Z

149

Evaluation of the Alere i Influenza A&B Nucleic Acid Amplification Test by Use of Respiratory Specimens Collected in Viral Transport Medium  

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...Influenza AB Nucleic Acid Amplification Test by Use of Respiratory Specimens Collected...to 19 years. Alere i Influenza AB assay test results were compared with viral culture...assays as their first-line diagnostic test for influenza virus infections. Though...

J. Jeremiah Bell; Rangaraj Selvarangan

2014-09-10T23:59:59.000Z

150

Heart Disease and Early Heart Attack Care  

E-Print Network (OSTI)

Heart Disease and Early Heart Attack Care Pamela Kostic, RN, CCCC, Chest Pain Coordinator, Stony Risk Factors · EHAC & Prevention #12;Heart disease includes a number of problems affecting the heart and the blood vessels in the heart. #12;Types of heart disease include: · Coronary artery disease (CAD) · Angina

Ohta, Shigemi

151

SAGE-Hindawi Access to Research Advances in Orthopedics  

E-Print Network (OSTI)

on titanium were grown by hydrothermal processing in one case and by anodization in the presence of dilute" titanium (cp Ti) coupons and implants. The methods included hydrothermal processing under different

Azad, Abdul-Majeed

152

Treatment of Ebola virus disease  

Science Journals Connector (OSTI)

As of October 17, 2014, a total of 9,216 cases of Ebola virus disease (EVD) and 4,555...1]. Assuming no change in the control measures for this epidemic, which seems to be the most realistic scenario for several ...

Yazdan Yazdanpanah; Jose Ramon Arribas; Denis Malvy

2014-11-01T23:59:59.000Z

153

Global mapping of infectious disease  

Science Journals Connector (OSTI)

...wide community of public health cartographers...patterns we observe in space and time? This level...disease in time and space, but also measure...operationally important public health inferences...model for mining public health topics from...NY: ACM Digital Library. 111 Kittur, A...

2013-01-01T23:59:59.000Z

154

Precision Nanomedicine in Neurodegenerative Diseases  

Science Journals Connector (OSTI)

Precision Nanomedicine in Neurodegenerative Diseases ... Laboratory of NanoMedicine, Department of Cell Research and Immunology, George S. Wise Faculty of Life Science, Department of Material Science and Engineering, and the Center for Nanoscience and Nanotechnology, Tel Aviv University, Tel Aviv 69978, Israel ... (16) This work may serve as a novel nanomedicine for therapeutic intervention in AD. ...

Meir Goldsmith; Lilach Abramovitz; Dan Peer

2014-03-25T23:59:59.000Z

155

Plant Diseases and Their Pathogens  

Science Journals Connector (OSTI)

Because this is a reference book and not one to be read for pleasure or continuity, most of you will come to the material you need in this section by way of the index or the lists of diseases given under the d...

R. Kenneth Horst Ph.D.

2001-01-01T23:59:59.000Z

156

Melanized Fungi in Human Disease  

Science Journals Connector (OSTI)

...Several blood culture systems are available, and...when making an initial assessment of fungal disease with...models of central nervous system infection with R. mackenziei...agents of central nervous system phaeohyphomycosis...Laboratory and clinical assessment of ketoconazole in deep-seated...

Sanjay G. Revankar; Deanna A. Sutton

2010-10-01T23:59:59.000Z

157

Plant Diseases and Their Pathogens  

Science Journals Connector (OSTI)

Because this book is for reference, and not one to be read for pleasure or continuity, most of you will come to the material you need in this section by way of the index or the lists of diseases given under th...

R. Kenneth Horst Ph.D.

1990-01-01T23:59:59.000Z

158

Landscape epidemiology of plant diseases  

Science Journals Connector (OSTI)

...1094/PHYTO-96-1027 Gilbert, G.S 2002Evolutionary ecology...phyto.40.021202.110417 Gilbert, G.S , S.P Hubbell...345 Webb, C.O , G.S Gilbert, and M.J Donoghue2006Phylodiversity-dependent...Pesticides Plant Diseases microbiology statistics & numerical data...

2007-01-01T23:59:59.000Z

159

Effects of Respiratory Motion on Passively Scattered Proton Therapy Versus Intensity Modulated Photon Therapy for Stage III Lung Cancer: Are Proton Plans More Sensitive to Breathing Motion?  

SciTech Connect

Purpose: To quantify and compare the effects of respiratory motion on paired passively scattered proton therapy (PSPT) and intensity modulated photon therapy (IMRT) plans; and to establish the relationship between the magnitude of tumor motion and the respiratory-induced dose difference for both modalities. Methods and Materials: In a randomized clinical trial comparing PSPT and IMRT, radiation therapy plans have been designed according to common planning protocols. Four-dimensional (4D) dose was computed for PSPT and IMRT plans for a patient cohort with respiratory motion ranging from 3 to 17 mm. Image registration and dose accumulation were performed using grayscale-based deformable image registration algorithms. The dosevolume histogram (DVH) differences (4D-3D [3D = 3-dimensional]) were compared for PSPT and IMRT. Changes in 4D-3D dose were correlated to the magnitude of tumor respiratory motion. Results: The average 4D-3D dose to 95% of the internal target volume was close to zero, with 19 of 20 patients within 1% of prescribed dose for both modalities. The mean 4D-3D between the 2 modalities was not statistically significant (P<.05) for all dosevolume histogram indices (mean SD) except the lung V5 (PSPT: +1.1% 0.9%; IMRT: +0.4% 1.2%) and maximum cord dose (PSPT: +1.5 2.9 Gy; IMRT: 0.0 0.2 Gy). Changes in 4D-3D dose were correlated to tumor motion for only 2 indices: dose to 95% planning target volume, and heterogeneity index. Conclusions: With our current margin formalisms, target coverage was maintained in the presence of respiratory motion up to 17 mm for both PSPT and IMRT. Only 2 of 11 4D-3D indices (lung V5 and spinal cord maximum) were statistically distinguishable between PSPT and IMRT, contrary to the notion that proton therapy will be more susceptible to respiratory motion. Because of the lack of strong correlations with 4D-3D dose differences in PSPT and IMRT, the extent of tumor motion was not an adequate predictor of potential dosimetric error caused by breathing motion.

Matney, Jason; Park, Peter C. [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); The University of Texas Graduate School of Biomedical Sciences, Houston, Texas (United States); Bluett, Jaques [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Chen, Yi Pei [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); The University of Texas Graduate School of Biomedical Sciences, Houston, Texas (United States); Liu, Wei; Court, Laurence E. [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Liao, Zhongxing [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Li, Heng [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Mohan, Radhe, E-mail: rmohan@mdanderson.org [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States)

2013-11-01T23:59:59.000Z

160

Crystallization of Mitochondrial Respiratory Complex II fromChicken Heart: A Membrane-Protein Complex Diffracting to 2.0Angstrom  

SciTech Connect

Procedure is presented for preparation of diffraction-quality crystals of a vertebrate mitochondrial respiratory Complex II. The crystals have the potential to diffract to at least 2.0 Angstrom with optimization of post-crystal-growth treatment and cryoprotection. This should allow determination of the structure of this important and medically relevant membrane protein complex at near-atomic resolution and provide great detail of the mode of binding of substrates and inhibitors at the two substrate-binding sites.

Huang, Li-shar; Borders, Toni M.; Shen, John T.; Wang, Chung-Jen; Berry, Edward A.

2004-12-17T23:59:59.000Z

Note: This page contains sample records for the topic "respiratory disease orthopedic" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


161

New Clues in Predicting Alzheimer's Disease  

ScienceCinema (OSTI)

Theres a new clue in the search to identify the harbingers of Alzheimers disease. More info: http://newscenter.lbl.gov/feature-stories/2008/12/16/predict-alzheimers-disease/

Jagust, William

2013-05-29T23:59:59.000Z

162

Christmas disease and haemophilia in Kenya  

Science Journals Connector (OSTI)

Christmas disease and haemophilia are thought to be rare in the African, but this paper reports 5 cases of Christmas disease and 5 of haemophilia in Kenyan Africans. With improvement in diagnostic facilities more cases will probably come to light.

Charles D. Forbes; Norman MacKay; Ashfaq Alam Khan

1966-01-01T23:59:59.000Z

163

Outbreaks of porcine parvovirus disease in Panama  

Science Journals Connector (OSTI)

The first recorded isolation of porcine parvovirus (PPV) in Panama is described. The outbreaks of PPV disease...

N. Obaldia III

1991-01-01T23:59:59.000Z

164

MENINGOCOCCAL DISEASE WHAT YOU NEED TO KNOW  

E-Print Network (OSTI)

, coughing and having close social contact (living in the same household) are examples of how this disease

Missouri-Rolla, University of

165

Heart Valve Disease James S. Gammie, MD  

E-Print Network (OSTI)

Heart Valve Disease James S. Gammie, MD Professor and Chief Division of Cardiac Surgery University USA Source: CDC #12;#12;CARDIOTHORACIC SURGEON: A SURGEON THAT TREATS HEART AND LUNG DISEASE #12;Valvular Heart Disease: Common and Under-diagnosed 0 2 4 6 8 10 12 14 18 - 44 45 - 54 55 - 64 65 - 74 > 75

Weber, David J.

166

Intraoral Radiology in Equine Dental Disease  

Science Journals Connector (OSTI)

Intraoral radiographs can be valuable aids in the diagnosis and management of equine dental disease. A step-by-step method is described for taking intraoral radiographs. Specific pathologic findings in equine dental disease are discussed. Utilization of this process facilitates diagnosis and treatment of dental disease and makes it possible to make a prognosis.

David O. Klugh

2005-01-01T23:59:59.000Z

167

Coronary Heart Disease, Hypertension, Stroke, and  

E-Print Network (OSTI)

Coronary Heart Disease, Hypertension, Stroke, and Diabetes #12;Coronary Heart Disease: Overview by atherosclerosis ­ Narrowing of coronary arteries, the vessels that supply the heart · Disease process: coronary and arms Myocardial infarction - heart attack, ischemia - local blood supply decreased resulting in cell

Meagher, Mary

168

Lyme Disease in Children in Southeastern Connecticut  

Science Journals Connector (OSTI)

...disease in southeastern Connecticut. Methods. Study Population. All children from five pediatric practices who were given a diagnosis of Lyme disease of recent onset were eligible to be enrolled in the study. The five pediatric practices are located in southeastern Connecticut, the area of the state with... Lyme disease has become a relatively common problem among children in areas of the country in which the disease is endemic.1,2 However, there are few prospective studies of the disease among children in the United States. Many parents fear that their ...

Gerber M.A.Shapiro E.D.Burke G.S.Parcells V.J.Bell G.L.

1996-10-24T23:59:59.000Z

169

E-Print Network 3.0 - asbestos-related pleuropulmonary diseases...  

NLE Websites -- All DOE Office Websites (Extended Search)

fibrosis of the lung Asbestos-related lung cancer: lung cancer, risk of contracting... mining and product manufacturing) can lead to a variety of respiratory ... Source: Flanagan,...

170

N1L Is an Ectromelia Virus Virulence Factor and Essential for In Vivo Spread upon Respiratory Infection  

Science Journals Connector (OSTI)

...early after infection. As described by Fenner (23), following initial replication...33, 40, 48). As early as 1949, Fenner suggested that the pathogenesis of mousepox...poxvirus disease. PLoS Pathog. 4: e30. 23 Fenner, F. 1948. The clinical features and...

Meike S. Gratz; Yasemin Suezer; Melanie Kremer; Asisa Volz; Monir Majzoub; Kay-Martin Hanschmann; Ulrich Kalinke; Astrid Schwantes; Gerd Sutter

2011-01-26T23:59:59.000Z

171

Chapter 9 - Ebola Virus Disease  

Science Journals Connector (OSTI)

Five species of ebolavirus constitute the genus Ebolavirus, one member of the Filoviridae family. The Bundibugyo, Zaire, and Sudan ebolavirus species cause severe Ebola virus disease (EVD) outbreaks in humans whereas the Reston and Ta Forest species do not. EVD is a febrile hemorrhagic illness, which causes death in 2590% of all clinically ill cases. EVD outbreaks occur primarily in remote villages in Central and West Africa, near tropical rainforests. The virus is transmitted to people from wild animals and spreads in the human population through human-to-human transmission. Fruit bats of the Pteropodidae family are considered to be the natural host of the Ebola virus. The laboratory diagnostic remains essential to confirm EVD cases. There is no treatment or vaccine available for either people or animals. Raising awareness of the risk factors of Ebola infection and the protective measures individuals can take is the only way to reduce human infection and death.

Pierre Formenty

2014-01-01T23:59:59.000Z

172

Therapeutic target for protozoal diseases  

DOE Patents (OSTI)

A novel Fasciclin Related Adhesive Protein (FRAP) from Plasmodium and related parasites is provided as a target for therapeutic intervention in diseases caused by the parasites. FRAP has been shown to play a critical role in adhesion to, or invasion into, host cells by the parasite. Furthermore, FRAP catalyzes the neutralization of heme by the parasite, by promoting its polymerization into hemozoin. This invention provides methods and compositions for therapies based on the administration of protein, DNA or cell-based vaccines and/or antibodies based on FRAP, or antigenic epitopes of FRAP, either alone or in combination with other parasite antigens. Methods for the development of compounds that inhibit the catalytic activity of FRAP, and diagnostic and laboratory methods utilizing FRAP are also provided.

Rathore, Dharmendar (Blacksburg, VA); Jani, Dewal (Blacksburg, VA); Nagarkatti, Rana (Blacksburg, VA)

2008-10-21T23:59:59.000Z

173

Soil Fumigation for Plant Disease Control.  

E-Print Network (OSTI)

AGRICULTURAL AND MECHANICAL COLLEGE OF TEXAS T- 0. WALTON, President [Blank Page in Original Bulletin] The control of soit-borne plant diseases by soil fumigation hm been nhown to be efficient and practicable in greenhouses, seed Ws, cold frames, small... diseases. Undesirable weeds are als~ frequently present. This bulletin deals with soil fumigation clesignecl especially to control these disease-producing organisms that infest the soil. It is based on experi- ments conducted in the last seven years...

Young, P. A. (Paul Allen); Godfrey, G. H. (George Harold)

1943-01-01T23:59:59.000Z

174

Enzyme replacement therapy for Pompe disease  

E-Print Network (OSTI)

Transport of Active Enzymes to Lysosomes. Molecular therapyOF CALIFORNIA, SAN DIEGO Enzyme Replacement Therapy forDisease 3 1.3 Enzyme Replacement Therapy for

Burris, Ryan Jonathan William

2010-01-01T23:59:59.000Z

175

"Artificial" brains, electrical grids, and disease modeling:...  

NLE Websites -- All DOE Office Websites (Extended Search)

Science discoveries unveiled "Artificial" brains, electrical grids, and disease modeling: Los Alamos science discoveries unveiled September 15 The event is an opportunity for...

176

Functional cardiovascular assessment in congenital heart disease.  

E-Print Network (OSTI)

??abstractAdequate and serial functional cardiovascular assessment is important in patients with congenital heart disease because many show disruption of normal myocardial geometry, which may or (more)

W.J.B.W. van den Berg

2007-01-01T23:59:59.000Z

177

Metabolic Prosthesis for Treating Ischemic Diseases - Energy...  

NLE Websites -- All DOE Office Websites (Extended Search)

have developed a new approach for treating ischemic diseases that will deliver oxygen directly to affected tissues by electrolysis of body fluids. Numerous treatments...

178

THE HUMAN GENOME & GENETIC DISEASES MED263: Bioinformatic Applications to Human Disease  

E-Print Network (OSTI)

you will learn. History of the human genome project Structure and content of the human genome HapTHE HUMAN GENOME & GENETIC DISEASES MED263: Bioinformatic Applications to Human Disease #12;WhatMap project Categories of Human Disease: Monogenic (Single gene disorders) Multigenic (Complex disorders

Gleeson, Joseph G.

179

Models of foot-and-mouth disease  

Science Journals Connector (OSTI)

...before focusing on the three foot-and-mouth disease models...their prevalence. However, foot-and-mouth disease (FMD...causes blisters on the mouth and feet (hence the name) and a deterioration...recent years, the computational power has become available to solve...

2005-01-01T23:59:59.000Z

180

HANFORD THYROID DISEASE STUDY FINAL REPORT  

E-Print Network (OSTI)

HANFORD THYROID DISEASE STUDY FINAL REPORT Study Management Team Scott Davis, Ph.D., Principal;Acknowledgments Many individuals have contributed to the success of the Hanford Thyroid Disease Study. We wish: Dr. Floyd Frost and Mr. Eugene Sobota; 3) history of Hanford: Dr. Michelle Stenejhem; 4) statistical

Note: This page contains sample records for the topic "respiratory disease orthopedic" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


181

Are You at Risk for Heart Disease?  

E-Print Network (OSTI)

vessels going to the heart get narrow and clogged. A heart attack can happen when these blood vesselsAre You at Risk for Heart Disease? Healthy Heart, Healthy Family Nangangamba Ka Bang Magkaroon ng Are You at Risk for Heart Disease? Healthy Heart, Healthy Family Nangangamba Ka Bang Magkaroon ng Sakit sa

Bandettini, Peter A.

182

PROTEIN INTERACTIONS AND DISEASE MARICEL KANN  

E-Print Network (OSTI)

and illnesses, including AIDS, cancer, and Alzheimer's disease. The goal of this session is to discuss interaction data to identify active pathways re- lated to HIV pathogenesis. A functional analysis for successful inference of protein interactions. Chen et al. developed a framework to mine disease

Radivojac, Predrag

183

Coronary Heart Disease, Hypertension, Stroke, and  

E-Print Network (OSTI)

Coronary Heart Disease, Hypertension, Stroke, and Diabetes #12;Coronary Heart Disease: Overview to illnesses caused by atherosclerosis ­ Narrowing of coronary arteries, the vessels that supply the heart that radiates across the chest and arms ? Myocardial infarction - heart attack, ischemia - local blood supply

Meagher, Mary

184

COLORED PHOTOGRAPHS OF PLANT DISEASE SPECIMENS  

Science Journals Connector (OSTI)

...DISEASE SPECIMENS IN the preparation of a handbook of the diseases of vegetables by the...World in 1893. In 1896 the American Electrician was established, and this magazine...a high order. In 1906 the American Electrician was absorbed by the Electrical World...

Max W. Gardner; Geo. K. K. Link

1920-06-04T23:59:59.000Z

185

Mitochondrial localization of fission yeast manganese superoxide dismutase is required for its lysine acetylation and for cellular stress resistance and respiratory growth  

SciTech Connect

Research highlights: {yields} Fission yeast manganese superoxide dismutase (MnSOD) is acetylated. {yields} The mitochondrial targeting sequence (MTS) is required for the acetylation of MnSOD. {yields} The MTS is not crucial for MnSOD activity, but is important for respiratory growth. {yields} Posttranslational regulation of MnSOD differs between budding and fission yeast. -- Abstract: Manganese-dependent superoxide dismutase (MnSOD) is localized in the mitochondria and is important for oxidative stress resistance. Although transcriptional regulation of MnSOD has been relatively well studied, much less is known about the protein's posttranslational regulation. In budding yeast, MnSOD is activated after mitochondrial import by manganese ion incorporation. Here we characterize posttranslational modification of MnSOD in the fission yeast Schizosaccharomyces pombe. Fission yeast MnSOD is acetylated at the 25th lysine residue. This acetylation was diminished by deletion of N-terminal mitochondrial targeting sequence, suggesting that MnSOD is acetylated after import into mitochondria. Mitochondrial localization of MnSOD is not essential for the enzyme activity, but is crucial for oxidative stress resistance and growth under respiratory conditions of fission yeast. These results suggest that, unlike the situation in budding yeast, S. pombe MnSOD is already active even before mitochondrial localization; nonetheless, mitochondrial localization is critical to allow the cell to cope with reactive oxygen species generated inside or outside of mitochondria.

Takahashi, Hidekazu, E-mail: hidetakahashi@riken.jp [Chemical Genetics Laboratory/Chemical Genomics Research Group, RIKEN Advanced Science Institute, Wako, Saitama 351-0198 (Japan)] [Chemical Genetics Laboratory/Chemical Genomics Research Group, RIKEN Advanced Science Institute, Wako, Saitama 351-0198 (Japan); Suzuki, Takehiro [Biomolecular Characterization Team, RIKEN Advanced Science Institute, Wako, Saitama 351-0198 (Japan) [Biomolecular Characterization Team, RIKEN Advanced Science Institute, Wako, Saitama 351-0198 (Japan); CREST Research Project, Japan Science and Technology Corporation, Kawaguchi, Saitama 332-0012 (Japan); Shirai, Atsuko; Matsuyama, Akihisa [Chemical Genetics Laboratory/Chemical Genomics Research Group, RIKEN Advanced Science Institute, Wako, Saitama 351-0198 (Japan)] [Chemical Genetics Laboratory/Chemical Genomics Research Group, RIKEN Advanced Science Institute, Wako, Saitama 351-0198 (Japan); Dohmae, Naoshi [Biomolecular Characterization Team, RIKEN Advanced Science Institute, Wako, Saitama 351-0198 (Japan) [Biomolecular Characterization Team, RIKEN Advanced Science Institute, Wako, Saitama 351-0198 (Japan); CREST Research Project, Japan Science and Technology Corporation, Kawaguchi, Saitama 332-0012 (Japan); Yoshida, Minoru, E-mail: yoshidam@riken.jp [Chemical Genetics Laboratory/Chemical Genomics Research Group, RIKEN Advanced Science Institute, Wako, Saitama 351-0198 (Japan) [Chemical Genetics Laboratory/Chemical Genomics Research Group, RIKEN Advanced Science Institute, Wako, Saitama 351-0198 (Japan); CREST Research Project, Japan Science and Technology Corporation, Kawaguchi, Saitama 332-0012 (Japan)

2011-03-04T23:59:59.000Z

186

What You Should Know About Plant Diseases.  

E-Print Network (OSTI)

of the organism can be a guide for the length of rotation. Resistant Varieties Planting disease-resistan t varieties can be the most economical way to control a disease. For many years plant breeders have been experiment- ing with the disease resistance... procedure. Ihy Heat-Small quantities of soil used in flower pots may be sterilized by placing in an oven set at 160 degrees F. for 3 to 4 hours. Electricity-Electricity may be used for steriliz- ing small quantities of boxed soil in which heating...

Horne, C. Wendell; Smith, Harlan E.

1962-01-01T23:59:59.000Z

187

Ultraviolet Germicidal Irradiation for Preventing Infectious Disease  

NLE Websites -- All DOE Office Websites (Extended Search)

Ultraviolet Germicidal Irradiation for Preventing Infectious Disease Ultraviolet Germicidal Irradiation for Preventing Infectious Disease Transmission Speaker(s): Peng Xu Date: February 19, 2002 - 12:00pm Location: Bldg. 90 The transmission of tuberculosis (TB) and other infectious diseases in health-care buildings has been a recognized hazard for decades. Ultraviolet germicidal irradiation (UVGI) of upper room air is used as an engineering control method to prevent the spread of airborne infectious disease. Under full-scale conditions, the efficacy of UVGI for inactivating airborne bacterial spores and active cells was evaluated. A test room fitted with a modern UVGI system was used to conduct bio-aerosol inactivation experiments. UVGI efficacy can be affected by environmental factors such as relative humidity (RH), and air mixing

188

Visualizing Brain Metals in Health and Disease  

NLE Websites -- All DOE Office Websites (Extended Search)

Visualizing Brain Metals in Health and Visualizing Brain Metals in Health and Disease figure 1 Fig. 1. Rapid-scanning x-ray fluorescence mapping ex perimental setup. Synchrotron x-rays at 11 keV passed through a 50 µm aperture (Ap). The beam intensity was monitored with a N2-filled ion chamber (I0). The brain slice was mounted vertically on a motorized stage (St) at 45° to the incident x-ray beam and raster scanned in the beam. A 13-element Ge detector (Ge) was positioned at a 90° angle to the beam. We all require iron, copper and zinc for normal brain function but metal metabolism becomes dysregulated in a variety of neurodegenerative diseases. Metals accumulate in Alzheimer's dementia and Parkinson's disease and are deficient in Menkes disease. Whether excess metals appear as a cause or a

189

INTERNATIONAL CENTRE FOR DIARRHOEAL DISEASE RESEARCH, BANGLADESH  

E-Print Network (OSTI)

©INTERNATIONAL CENTRE FOR DIARRHOEAL DISEASE RESEARCH, BANGLADESH J HEALTH POPUL NUTR 2009 00 managers can target resources to identify if such clusters exist. If so, they can then ensure supervi

Scharfstein, Daniel

190

Fracture, aging and disease in bone  

E-Print Network (OSTI)

by enhancing the materials resistance to microstructuralgrowth resistance of microcracking brittle materials. J. Am.resistance to fracture of the Page 4 Fracture, Aging and Disease in Bone underlying material.

Ager, J.W.; Balooch, G.; Ritchie, R.O.

2006-01-01T23:59:59.000Z

191

Interferon antibodies in patients with infectious diseases  

Science Journals Connector (OSTI)

Interferons (IFNs) are generally recognized as the most important therapeutic agent in some infectious diseases such as chronic hepatitis B and C. Since the early clinical trials it was documented that the the...

G. Antonelli; E. Simeoni; M. Currenti; F. De Pisa; V. Colizzi

1997-01-01T23:59:59.000Z

192

Online GIS services for mapping and sharing disease information  

Science Journals Connector (OSTI)

Disease data sharing is important for the collaborative preparation, response, and recovery stages of disease control. Disease phenomena are strongly associated with spatial and temporal factors. Web-based Geo...

Sheng Gao; Darka Mioc; Francois Anton

2008-02-01T23:59:59.000Z

193

Foot and mouth disease in Iraq: strategy and control.  

E-Print Network (OSTI)

??Foot-and-mouth disease (FMD) is a highly infectious viral disease of cattle, pigs, sheep, goats, buffalo, and artiodactyl wildlife species. Foot-and-mouth disease virus is endemic and (more)

Mahdi, Ali Jafar

2010-01-01T23:59:59.000Z

194

on Infectious & Reportable Diseases HEALTH & SAFETY UNIT MAY 2009  

E-Print Network (OSTI)

POLICY on Infectious & Reportable Diseases HEALTH & SAFETY UNIT MAY 2009 #12;Policy on Infectious .......................................................................................... 6 5.2 Public Health (Infectious Diseases) Regulations 1988 ............................. 6 5.3 Reporting of Injuries, Diseases & Dangerous Occurrences Regulations 1995

195

Prevent the Spread of Zoonotic Diseases  

E-Print Network (OSTI)

Take Precautions when Handling and Caring for Animals During routine care of animals, take the following precautions against spread- ing germs that cause diseases. Wear personal protective clothing and equipment Personal protective clothing, boots..., and equipment can reduce the risk of exposing other animals or people to contagious diseases. Wear boots and a set of protective clothing that you wear only when ? handling and caring for animals. Examples are hat ? coveralls ? long-sleeved shirt (cotton...

Pena, Josefa

2008-11-10T23:59:59.000Z

196

alzheimer's disease: Topics by E-print Network  

NLE Websites -- All DOE Office Websites (Extended Search)

and memory deterioration, a clinical hallmark of Alzheimer's disease that the primary factor in the pathogenesis of cognitive de ciencies in Alzheimer's disease is the...

197

Commercial Pecans: Controlling Rosette, Diseases and Zinc Deficiency  

E-Print Network (OSTI)

Pecan losses from diseases and insufficient zinc nutrition can be prevented by following effective grove management practices. Descriptions of diseases and recommendations for controls are included....

Lee, Thomas A.; Krausz, Joseph P.

2006-04-13T23:59:59.000Z

198

Disease-Specific Symptoms and Health-Related Quality of Life in Children and Adolescents with Inflammatory Bowel Disease  

E-Print Network (OSTI)

This study assesses generic and disease-specific Health-Related Quality of Life (HRQOL) in children and adolescents with Inflammatory Bowel Disease (IBD). More specifically, the purpose of the study is to address the relationship between disease...

Vaughan-Dark, Chelsea Ann

2013-07-17T23:59:59.000Z

199

Genetic Studies of Complex Human Diseases: Characterizing SNP-Disease Associations Using Bayesian Networks  

E-Print Network (OSTI)

Detecting epistatic interactions plays a significant role in improving pathogenesis, prevention, diagnosis, and treatment of complex human diseases. Applying machine learning or statistical methods to epistatic interaction ...

Han, Bing; Chen, Xue-wen; Talebizadeh, Zohreh; Xu, Hua

2012-12-17T23:59:59.000Z

200

Comparison of Rigid and Adaptive Methods of Propagating Gross Tumor Volume Through Respiratory Phases of Four-Dimensional Computed Tomography Image Data Set  

SciTech Connect

Purpose: To compare three different methods of propagating the gross tumor volume (GTV) through the respiratory phases that constitute a four-dimensional computed tomography image data set. Methods and Materials: Four-dimensional computed tomography data sets of 20 patients who had undergone definitive hypofractionated radiotherapy to the lung were acquired. The GTV regions of interest (ROIs) were manually delineated on each phase of the four-dimensional computed tomography data set. The ROI from the end-expiration phase was propagated to the remaining nine phases of respiration using the following three techniques: (1) rigid-image registration using in-house software, (2) rigid image registration using research software from a commercial radiotherapy planning system vendor, and (3) rigid-image registration followed by deformable adaptation originally intended for organ-at-risk delineation using the same software. The internal GTVs generated from the various propagation methods were compared with the manual internal GTV using the normalized Dice similarity coefficient (DSC) index. Results: The normalized DSC index of 1.01 {+-} 0.06 (SD) for rigid propagation using the in-house software program was identical to the normalized DSC index of 1.01 {+-} 0.06 for rigid propagation achieved with the vendor's research software. Adaptive propagation yielded poorer results, with a normalized DSC index of 0.89 {+-} 0.10 (paired t test, p <0.001). Conclusion: Propagation of the GTV ROIs through the respiratory phases using rigid- body registration is an acceptable method within a 1-mm margin of uncertainty. The adaptive organ-at-risk propagation method was not applicable to propagating GTV ROIs, resulting in an unacceptable reduction of the volume and distortion of the ROIs.

Ezhil, Muthuveni [Department of Radiation Physics, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States)], E-mail: veniezhil@hotmail.com; Choi, Bum; Starkschall, George [Department of Radiation Physics, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Bucci, M. Kara [Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States); Vedam, Sastry; Balter, Peter [Department of Radiation Physics, University of Texas M. D. Anderson Cancer Center, Houston, TX (United States)

2008-05-01T23:59:59.000Z

Note: This page contains sample records for the topic "respiratory disease orthopedic" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


201

E-Print Network 3.0 - adults cardiovascular disease Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

disease, the number one killer of all Americans. Cardiovascular disease, or heart disease is the primary cause Summary: Kidney disease is both a cause and a consequence...

202

E-Print Network 3.0 - affect cardiovascular disease Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

disease, the number one killer of all Americans. Cardiovascular disease, or heart disease is the primary cause Summary: Kidney disease is both a cause and a consequence...

203

E-Print Network 3.0 - addressing cardiovascular disease Sample...  

NLE Websites -- All DOE Office Websites (Extended Search)

disease, the number one killer of all Americans. Cardiovascular disease, or heart disease is the primary cause Summary: Kidney disease is both a cause and a consequence...

204

Some properties of a simple stochastic epidemic model of SIR type  

E-Print Network (OSTI)

illness and mortality across the globe. New diseases, such as ebola, severe acute respiratory syndrome

205

Nanomedicine approaches in vascular disease: a review  

Science Journals Connector (OSTI)

Nanomedicine approaches have revolutionized the treatment of cancer and vascular diseases, where the limitations of rapid nonspecific clearance, poor biodistribution and harmful side effects associated with direct systemic drug administration can be overcome by packaging the agents within sterically stabilized, long-circulating nanovehicles that can be further surface-modified with ligands to actively target cellular/molecular components of the disease. With significant advancements in genetics, proteomics, cellular and molecular biology and biomaterials engineering, the nanomedicine strategies have become progressively refined regarding the modulation of surface and bulk chemistry of the nanovehicles, control of drug release kinetics, manipulation of nanoconstruct geometry and integration of multiple functionalities on single nanoplatforms. The current review aims to capture the various nanomedicine approaches directed specifically toward vascular diseases during the past two decades. Analysis of the promises and limitations of these approaches will help identify and optimize vascular nanomedicine systems to enhance their efficacy and clinical translation in the future. From the Clinical Editor Nanomedicine-based approaches have had a major impact on the treatment and diagnosis of malignancies and vascular diseases. This review discusses various nanomedicine approaches directed specifically toward vascular diseases during the past two decades, highlighting their advantages, limitations and offering new perspectives on future applications.

Anirban Sen Gupta

2011-01-01T23:59:59.000Z

206

The mathematics of diseases On Modeling Hong Kong's SARS Outbreak  

E-Print Network (OSTI)

The mathematics of diseases ­ On Modeling Hong Kong's SARS Outbreak Dr. Tuen Wai Ng Department disease modeling Epidemics: bovine spongiform encephalopathy (mad cow disease) Chicken flu #12;Infectious disease modeling Mathematical models can: predict rate of spread, peak, etc., of epidemics predict effects

Ng, Tuen Wai "Patrick"

207

CAMB 630 Topics in Human Genetics and Disease Course Directors  

E-Print Network (OSTI)

on the foundations of the Human Genome Project and parallel efforts in model organisms, research in human genetics in Human Genetics and Disease: I. Genome architecture and instability (Spinner) Chromosome specific of Mendelian disease Developmental pathways and genetic disease III. Human genomic variation and disease

Plotkin, Joshua B.

208

Texas Plant Disease Diagnostic Lab Information Form  

E-Print Network (OSTI)

Specific test required: Additional cost: see http://plantclinic.tamu.edu for fees. Culture ? Oak wilt ? DED ELISA ? Pierce?s disease (grape) ? Bacterial leaf scorch ? Virus ? Other: ______________ PLANT DISEASE DIAGNOSIS FORM D...: report unless specified ? do not notify Recent pesticide & chemical application Product name Date Fertilizer(s) Fungicide(s) Insecticide(s) Herbicide(s) Other Th e T e x a s P l a n t D i s e a s e D i a g n o st i c L a b o r a t o r y ( T P D D L...

Barnes, Larry W.

2009-01-16T23:59:59.000Z

209

Deep-Brain Stimulation for Parkinson's Disease  

Science Journals Connector (OSTI)

...are related to electrical stimulation and may be addressed by adjustment of device programming or discontinuation of therapy. Neurologic side effects of deep-brain stimulation include cognitive impairment, memory deficits, difficulties with speech, disequilibrium, dysphagia, and motor and sensory disturbances... A 72-year-old man with Parkinson's disease is referred for consideration of deep-brain stimulation, which involves the implantation of electrodes in one of the nuclei of the basal ganglia and can result in significant improvement in some symptoms of Parkinson's disease.

Okun M.S.

2012-10-18T23:59:59.000Z

210

Rapid molecular theranostics in infectious diseases  

Science Journals Connector (OSTI)

The increasing availability of rapid and sensitive nucleic acid testing assays for infectious diseases will revolutionize the practice of medicine by gradually reducing the need for standard culture-based microbiological methods that take at least two days. Molecular theranostics in infectious diseases is an emerging concept in which molecular biology tools are used to provide rapid and accurate diagnostic assays to enable better initial management of patients and more efficient use of antimicrobials. Essential conditions and the quality control required for the development and validation of such molecular theranostic assays are reviewed.

Franois J Picard; Michel G Bergeron

2002-01-01T23:59:59.000Z

211

Minimal Residual Disease in Chronic Myeloid Leukemia  

Science Journals Connector (OSTI)

...treatment with chemotherapy. In a hematologic complete remission, we know that a large portion of the leukemic cells remain out of sight. These cells, invisible to the microscopist, are the components of an important clinical problem termed "minimal residual disease." The concept of minimal residual disease... For many years hematologists have used the microscope to identify a complete remission of leukemia after treatment with chemotherapy. In a hematologic complete remission, we know that a large portion of the leukemic cells remain out of sight. These cells, ...

Lwenberg B.

2003-10-09T23:59:59.000Z

212

Purdue Extension Muskmelon and Watermelon Diseases  

E-Print Network (OSTI)

to muskmelons than watermelons. The disease is caused by a fungus (Alternaria cucumerina) that can rapidly Conditions · A brief introduction to the Melcast concept. III. Using Melcast · Acquiring Environmental Data - A description of data requirements for running Melcast. · Translating Environmental Data into EFI Values

213

Vaccine approaches with Edinburgh Infectious Diseases  

E-Print Network (OSTI)

Vaccine approaches with Edinburgh Infectious Diseases Alexander Corbishley #12;The technology approaches to knowledge exchange · October 2013: three technology scouts seconded for 12 months, to identify Congress 2014 (Washington DC) · Local partnering meetings with SMEs · Discussions with Open Innovation

Maizels, Rick

214

COGNITIVE NEUROLOGY AND ALZHEIMER'S DISEASE CENTER  

E-Print Network (OSTI)

the use of memantine (Namenda®) in those with a diagnosis of frontotemporal dementia (FTD). Memantine's disease suggests memantine may reduce damage to brain cells and therefore may also be effective in people with FTD. This study is designed to evaluate the safety and tolerability of memantine in FTD

Chisholm, Rex L.

215

MFR PAPER 1143 A Septicemic Bacterial Disease  

E-Print Network (OSTI)

in Galveston. Mortalities from this disease ranged from a few shrimp lost per day in some cases to nearly 100 of Veterinary Microbiology, Texas A&M Univer- sity, College Station, TX 77843. This paper is Contribution No. 372 of the Galveston Laboratory, Gulf Coastal Fisheries Center, NMFS, NOAA, Galveston, TX 77550. food

216

A Comparison of Amplitude-Based and Phase-Based Positron Emission Tomography Gating Algorithms for Segmentation of Internal Target Volumes of Tumors Subject to Respiratory Motion  

SciTech Connect

Purpose: To quantitatively compare the accuracy of tumor volume segmentation in amplitude-based and phase-based respiratory gating algorithms in respiratory-correlated positron emission tomography (PET). Methods and Materials: List-mode fluorodeoxyglucose-PET data was acquired for 10 patients with a total of 12 fluorodeoxyglucose-avid tumors and 9 lymph nodes. Additionally, a phantom experiment was performed in which 4 plastic butyrate spheres with inner diameters ranging from 1 to 4 cm were imaged as they underwent 1-dimensional motion based on 2 measured patient breathing trajectories. PET list-mode data were gated into 8 bins using 2 amplitude-based (equal amplitude bins [A1] and equal counts per bin [A2]) and 2 temporal phase-based gating algorithms. Gated images were segmented using a commercially available gradient-based technique and a fixed 40% threshold of maximum uptake. Internal target volumes (ITVs) were generated by taking the union of all 8 contours per gated image. Segmented phantom ITVs were compared with their respective ground-truth ITVs, defined as the volume subtended by the tumor model positions covering 99% of breathing amplitude. Superior-inferior distances between sphere centroids in the end-inhale and end-exhale phases were also calculated. Results: Tumor ITVs from amplitude-based methods were significantly larger than those from temporal-based techniques (P=.002). For lymph nodes, A2 resulted in ITVs that were significantly larger than either of the temporal-based techniques (P<.0323). A1 produced the largest and most accurate ITVs for spheres with diameters of ?2 cm (P=.002). No significant difference was shown between algorithms in the 1-cm sphere data set. For phantom spheres, amplitude-based methods recovered an average of 9.5% more motion displacement than temporal-based methods under regular breathing conditions and an average of 45.7% more in the presence of baseline drift (P<.001). Conclusions: Target volumes in images generated from amplitude-based gating are larger and more accurate, at levels that are potentially clinically significant, compared with those from temporal phase-based gating.

Jani, Shyam S., E-mail: sjani@mednet.ucla.edu [Department of Radiation Oncology, David Geffen School of Medicine, University of California, Los Angeles, California (United States); Robinson, Clifford G. [Department of Radiation Oncology, Siteman Cancer Center, Washington University in St Louis, St Louis, Missouri (United States); Dahlbom, Magnus [Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, California (United States); White, Benjamin M.; Thomas, David H.; Gaudio, Sergio; Low, Daniel A.; Lamb, James M. [Department of Radiation Oncology, David Geffen School of Medicine, University of California, Los Angeles, California (United States)

2013-11-01T23:59:59.000Z

217

Exclusion map of Salla disease: attempts to localize the disease gene using a computer program  

Science Journals Connector (OSTI)

Salla disease is a lysosomal storage disorder due to impaired transport of free sialic acid across the lysosomal membrane. The clinical presentation of this autosomal recessive trait is severe psychomotor reta...

Leena Haataja; Johanna Schlentker; Martin Renlund; Aarno Palotie

1992-01-01T23:59:59.000Z

218

Modeling social response to the spread of an infectious disease  

E-Print Network (OSTI)

With the globalization of culture and economic trade, it is increasingly important not only to detect outbreaks of infectious disease early, but also to anticipate the social response to the disease. In this thesis, we use ...

Evans, Jane A. (Jane Amanda)

2012-01-01T23:59:59.000Z

219

Harvesting can increase severity of wildlife disease epidemics  

Science Journals Connector (OSTI)

...classes. In our model, neither catchability...However, we can predict that, in figure...infects rabbits. Our model could also potentially...disease like the avian flu that currently threatens...Resources Disease Outbreaks veterinary Models, Biological Population...

2006-01-01T23:59:59.000Z

220

Air Pollution and Oxidative Stress in Allergic Airway Diseases  

Science Journals Connector (OSTI)

With 3040 % of the worlds population suffering from allergic diseases and with the increasing trends of this noncommunicable disease, especially in children in both the developed and developing, allergic diseas...

Ruby Pawankar M.D.; Ph.D.; F.R.C.P.; F.A.A.A.A.I.

2014-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "respiratory disease orthopedic" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


221

Infectious Disease Modeling of Social Contagion in Networks  

E-Print Network (OSTI)

Many behavioral phenomena have been found to spread interpersonally through social networks, in a manner similar to infectious diseases. An important difference between social contagion and traditional infectious diseases, ...

Hill, Alison Lynn

222

Characterization of a Drosophila model of Huntington's disease  

E-Print Network (OSTI)

Huntington's disease (HD) is an autosomal dominant neurological disorder caused by a polyglutamine (polyQ) repeat expansion in the huntingtin (Htt) protein. The disease is characterized by neurodegeneration and formation ...

Lee, Wyan-Ching Mimi

2006-01-01T23:59:59.000Z

223

Preventing diet induced disease: bioavailable nutrient-rich, low-  

E-Print Network (OSTI)

induced disease, including the use of food nanotechnology. nanotechnology promises to transform medicine intake and noting the importance of cofactors). Micro- and nanotechnologies are already engineering nano problems and challenges for society). Key words: nanotechnology, diet, disease, cardiovascular, heart

Paris-Sud XI, Université de

224

University Guidance for the REPORTING OF ACCIDENTS, DISEASES AND  

E-Print Network (OSTI)

University Guidance for the REPORTING OF ACCIDENTS, DISEASES AND DANGEROUS OCCURANCES HEALTH INJURY, HOSPITALISATION, DISEASE AND DANGEROUS OCCURRENCES.2 Reporting Over Three Days Absence Injury.........................................2 4.3 Reporting a Dangerous

225

Women and Heart Disease: Neglected Directions for Future Research  

E-Print Network (OSTI)

009-9110-0 Women and Heart Disease: Neglected Directions forage 65, women have less heart disease than men. For many1980s showed a lower risk of heart attacks in postmenopausal

Barrett-Connor, Elizabeth

2009-01-01T23:59:59.000Z

226

Former Workers Medical Facilities with Experience Evaluating Chronic Beryllium Disease  

Energy.gov (U.S. Department of Energy (DOE))

This document provides a listing of medical facilities within the United States with experience in evaluating Chronic Beryllium Disease.

227

Donepezil and Memantine for Moderate-to-Severe Alzheimer's Disease  

Science Journals Connector (OSTI)

...when Alzheimer's disease becomes severe. Evidence of the efficacy of memantine has been shown primarily in patients with moderate or severe Alzheimer's disease. The findings of a study showing that combination therapy with memantine and a cholinesterase inhibitor was more effective than treatment with... Most studies evaluating cholinesterase inhibitors for the treatment of Alzheimer's disease have focused on patients with mild-to-moderate disease. Despite questions about the methods used in the trials1 and about the clinical significance of reported ...

Howard R.; McShane R.; Lindesay J.

2012-03-08T23:59:59.000Z

228

Annular lichen planus in association with Crohn disease  

E-Print Network (OSTI)

of Crohn disease and a sickle cell trait. Therapy withparasites were excluded. Sickle cell trait was diagnosed (

Serro, Vasco Vieira; Organ, Vasili; Pereira, Lus; Vale, Esmeralda; Correia, Suzete

2008-01-01T23:59:59.000Z

229

RESEARCH OF ANIMAL DISEASE INFORMATION SYSTEM BASED ON GIS  

E-Print Network (OSTI)

in order to dynamically monitor and predict diseases distribution, and propagation, such as HPAI and FMD monitor and predict disease, as well as to support the disease prevention decision making, in order outbreak and propagation in some areas of China, . With HPAI for example,, in 2005 there were 13 areas

Boyer, Edmond

230

Modeling daily flow patterns individuals to characterize disease spread  

SciTech Connect

The effect of an individual's travels throughout a day on the spread of disease is examined using a deterministic SIR model. We determine which spatial and demographic characteristics most contribute to the disease spread and whether the progression of the disease can be slowed by appropriate vaccination of people belonging to a specific location-type.

Smallwood, J. (Jeanine); Hyman, J. M. (James M.); Mirchandani, Pitu B.

2002-11-17T23:59:59.000Z

231

Rapid evolutionary dynamics and disease threats to biodiversity  

E-Print Network (OSTI)

Rapid evolutionary dynamics and disease threats to biodiversity Sonia Altizer1 , Drew Harvell2 should enable hosts to respond better to future disease threats. Infectious diseases are recognized populations, or have been implicated as threats to already declining species [4­6]. Although infectious

232

A Century of Progress: Milestones in Sickle Cell Disease  

E-Print Network (OSTI)

A Century of Progress: Milestones in Sickle Cell Disease Research and Care Introduction In 1910 to be known as sickle cell disease. One hundred years later we know that the sickle-shaped cells are due take the characteristic "C"-shape that is the hallmark of sickle cell disease. What is Sickle Cell

Bandettini, Peter A.

233

Horticultural & Forest crops 2014 Floral Crops: Diseases 5-1  

E-Print Network (OSTI)

Horticultural & Forest crops 2014 Floral Crops: Diseases 5-1 Diseases Chuan Hong, Plant Pathologist humidity, low light intensity, and frequent watering, are favorable for the development of fungal and bacterial diseases. If insects are uncontrolled in the greenhouse, viruses can become a major problem

Liskiewicz, Maciej

234

The Clinical Differentiation of Primary Gout from Primary Renal Disease in Patients with Both Gout and Renal Disease  

Science Journals Connector (OSTI)

Renal disease is a well recognized complication of primary gout but it is less well recognized that ... patients with primary renal disease may also develop gout. Chronic lead nephropathy is the best recognized ....

B. T. Emmerson; P. J. Stride; Gail Williams

1980-01-01T23:59:59.000Z

235

Disparities in Emergency Department Quality of Care among Patients with and without Coronary Heart Disease Diagnoses  

E-Print Network (OSTI)

coronary heart disease and heart attack, and perceive theyheart disease and heart attack, and tend to perceive thatfor heart disease and heart attack, and do not recognize

Sammartinova, Jitka

2013-01-01T23:59:59.000Z

236

E-Print Network 3.0 - assessing disease activity Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

The disease... candidate genes for diverse diseases, even in the absence of text mining data. Gene-centric assessment... This evaluation treats each known gene-disease ......

237

E-Print Network 3.0 - advanced eye disease Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

Safety PRogRam Summary: . Leptospirosis Leptospirosis is a bacterial disease that causes abortion, eye problems and kidney disease... Horse Transmitted DiseasesSaddle Up SAFELY...

238

Analysis of Dose Response for Circulatory Disease After Radiotherapy for Benign Disease  

SciTech Connect

Purpose: To assess the shape of the dose-response for various circulatory disease endpoints, and modifiers by age and time since exposure. Methods and Materials: This was an analysis of the US peptic ulcer data testing for heterogeneity of radiogenic risk by circulatory disease endpoint (ischemic heart, cerebrovascular, other circulatory disease). Results: There were significant excess risks for all circulatory disease, with an excess relative risk Gy{sup -1} of 0.082 (95% CI 0.031-0.140), and ischemic heart disease, with an excess relative risk Gy{sup -1} of 0.102 (95% CI 0.039-0.174) (both p = 0.01), and indications of excess risk for stroke. There were no statistically significant (p > 0.2) differences between risks by endpoint, and few indications of curvature in the dose-response. There were significant (p < 0.001) modifications of relative risk by time since exposure, the magnitude of which did not vary between endpoints (p > 0.2). Risk modifications were similar if analysis was restricted to patients receiving radiation, although the relative risks were slightly larger and the risk of stroke failed to be significant. The slopes of the dose-response were generally consistent with those observed in the Japanese atomic bomb survivors and in occupationally and medically exposed groups. Conclusions: There were excess risks for a variety of circulatory diseases in this dataset, with significant modification of risk by time since exposure. The consistency of the dose-response slopes with those observed in radiotherapeutically treated groups at much higher dose, as well as in lower dose-exposed cohorts such as the Japanese atomic bomb survivors and nuclear workers, implies that there may be little sparing effect of fractionation of dose or low-dose-rate exposure.

Little, Mark P., E-mail: mark.little@nih.gov [Radiation Epidemiology Branch, National Cancer Institute, Executive Plaza South, Rockville, Maryland (United States); Kleinerman, Ruth A. [Radiation Epidemiology Branch, National Cancer Institute, Executive Plaza South, Rockville, Maryland (United States)] [Radiation Epidemiology Branch, National Cancer Institute, Executive Plaza South, Rockville, Maryland (United States); Stovall, Marilyn; Smith, Susan A. [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States)] [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Mabuchi, Kiyohiko [Radiation Epidemiology Branch, National Cancer Institute, Executive Plaza South, Rockville, Maryland (United States)] [Radiation Epidemiology Branch, National Cancer Institute, Executive Plaza South, Rockville, Maryland (United States)

2012-12-01T23:59:59.000Z

239

A study of the pecan shuck disease  

E-Print Network (OSTI)

29 Micro. 28 + Macro. 27 10 11 Cyprex 12 33 Mi cro . 34 + Zinc 35 36 37 Zinc 38 26 25 24 23 22 21 Micro. Cyprex + Macro. 13 Cyprex 14 + Micro. 15 16 Cyprex 17 + Zinc 18 0 I a 'o tU 4J m w 4J o 39 20 19... in the study of the effect of various treatments on the incidence of pecan shuck disease. 12 Fig. 3-3. John Bean sprayer used to make the foliar applications of zinc, Cyprex fungicide and microelements. A) Front view, B) Side view. 13 Table 3...

Williams, James Mclaren

1969-01-01T23:59:59.000Z

240

Hunger and Socioeconomic Disparities in Chronic Disease  

Science Journals Connector (OSTI)

...healthful foods could stem the tide of widening socioeconomic disparities in chronic disease. In developing and newly industrialized countries worldwide, food insecurity in the context of the globalization of food markets exposes low-income populations to the same low-cost, energy-dense, and nutritionally... The rate of food insecurity rose by 32% in 2008, to 14.6% of U.S. households. Drs. Hilary Seligman and Dean Schillinger argue that the widening price differential between unhealthful and healthful foods may increase socioeconomic disparities in the ...

Seligman H.K.; Schillinger D.

2010-07-01T23:59:59.000Z

Note: This page contains sample records for the topic "respiratory disease orthopedic" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


241

Crohn's disease and the mycobacterioses: a review and comparison of two disease entities.  

Science Journals Connector (OSTI)

...after all? Dig. Dis. Sci. 29:1086-1088. 97. Gitnick, G., J...Thailand. Rev. Infect. Dis. 3:1085-1089. 264. Sroat, D. A. 1988. Ocular...disease. Dig. Dis. Sci. 29:1080-1085. 275. Thayer, W. R., B. Fixa...

R J Chiodini

1989-01-01T23:59:59.000Z

242

Rare is frequent and frequent is costly: rare diseases as a challenge for health care systems  

Science Journals Connector (OSTI)

Of 30,000 known diseases about 6,0007,000 are defined as rare diseases, also commonly known as orphan diseases [1]. Within the European Union (EU), rare diseases are specified as indications with a prevalence of...

J.-Matthias Graf von der Schulenburg

2014-10-01T23:59:59.000Z

243

Chronic Beryllium Disease Prevention Program Report  

SciTech Connect

This document describes how Lawrence Livermore National Laboratory (LLNL) meets the requirements and management practices of federal regulation 10 CFR 850, 'Chronic Beryllium Disease Prevention Program (CBDPP).' This revision of the LLNL CBDPP incorporates clarification and editorial changes based on lessons learned from employee discussions, observations and reviews of Department of Energy (DOE) Complex and commercial industry beryllium (Be) safety programs. The information is used to strengthen beryllium safety practices at LLNL, particularly in the areas of: (1) Management of small parts and components; and (2) Communication of program status to employees. Future changes to LLNL beryllium activities and on-going operating experience will be incorporated into the program as described in Section S, 'Performance Feedback.'

Lee, S

2012-03-29T23:59:59.000Z

244

Automated diagnostic kiosk for diagnosing diseases  

DOE Patents (OSTI)

An automated and autonomous diagnostic apparatus that is capable of dispensing collection vials and collections kits to users interesting in collecting a biological sample and submitting their collected sample contained within a collection vial into the apparatus for automated diagnostic services. The user communicates with the apparatus through a touch-screen monitor. A user is able to enter personnel information into the apparatus including medical history, insurance information, co-payment, and answer a series of questions regarding their illness, which is used to determine the assay most likely to yield a positive result. Remotely-located physicians can communicate with users of the apparatus using video tele-medicine and request specific assays to be performed. The apparatus archives submitted samples for additional testing. Users may receive their assay results electronically. Users may allow the uploading of their diagnoses into a central databank for disease surveillance purposes.

Regan, John Frederick; Birch, James Michael

2014-02-11T23:59:59.000Z

245

FISH CONSUMPTION, METHYLMERCURY, AND HUMAN HEART DISEASE.  

SciTech Connect

Environmental mercury continues to be of concern to public health advocates, both in the U.S. and abroad, and new research continues to be published. A recent analysis of potential health benefits of reduced mercury emissions has opened a new area of public health concern: adverse effects on the cardiovascular system, which could account for the bulk of the potential economic benefits. The authors were careful to include caveats about the uncertainties of such impacts, but they cited only a fraction of the applicable health effects literature. That literature includes studies of the potentially harmful ingredient (methylmercury, MeHg) in fish, as well as of a beneficial ingredient, omega-3 fatty acids or ''fish oils''. The U.S. Food and Drug Administration (FDA) recently certified that some of these fat compounds that are primarily found in fish ''may be beneficial in reducing coronary heart disease''. This paper briefly summarizes and categorizes the extensive literature on both adverse and beneficial links between fish consumption and cardiovascular health, which are typically based on studies of selected groups of individuals (cohorts). Such studies tend to comprise the ''gold standard'' of epidemiology, but cohorts tend to exhibit a great deal of variability, in part because of the limited numbers of individuals involved and in part because of interactions with other dietary and lifestyle considerations. Note that eating fish will involve exposure to both the beneficial effects of fatty acids and the potentially harmful effects of contaminants like Hg or PCBs, all of which depend on the type of fish but tend to be correlated within a population. As a group, the cohort studies show that eating fish tends to reduce mortality, especially due to heart disease, for consumption rates up to about twice weekly, above which the benefits tend to level off. A Finnish cohort study showed increased mortality risks in the highest fish-consuming group ({approx}3 times/wk), which had mercury exposures (mean hair content of 3.9 ppm) much higher than those seen in the United States. As an adjunct to this cursory review, we also present some new ''ecological'' analyses based on international statistics on hair Hg, fish consumption, other dietary and lifestyle factors, and selected cardiovascular health endpoints. We searched for consistent differences between primarily fish-consuming nations, like Japan or the Seychelles, and others who traditionally eat much less fish , such as in central Europe, for example. We use data on cigarette sales, smoking prevalence surveys, and national lung cancer mortality rates to control for the effects of smoking on heart disease. These ecological analyses do not find significant adverse associations of either fish consumption or hair Hg with cardiovascular health; instead, there is a consistent trend towards beneficial effects, some of which are statistically significant. However, such ecological studies cannot distinguish differences due to variations in individual rates of fish consumption. We conclude that the extant epidemiological evidence does not support the existence of significant heart disease risks associated with mercury in fish, for the United States. The most prudent advice would continue to be that of maintaining a well-balanced diet, including fish or shellfish at least once per week. There may be additional benefits from fatty fish.

LIPFERT, F.W.; SULLIVAN, T.M.

2005-09-21T23:59:59.000Z

246

Networks and the Epidemiology of Infectious Disease  

E-Print Network (OSTI)

The science of networks has revolutionised research into the dynamics of interacting elements. It could be argued that epidemiology in particular has embraced the potential of network theory more than any other discipline. Here we review the growing body of research concerning the spread of infectious diseases on networks, focusing on the interplay between network theory and epidemiology. The review is split into four main sections, which examine: the types of network relevant to epidemiology; the multitude of ways these networks can be characterised; the statistical methods that can be applied to infer the epidemiological parameters on a realised network; and finally simulation and analytical methods to determine epidemic dynamics on a given network. Given the breadth of areas covered and the ever-expanding number of publications, a comprehensive review of all work is impossible. Instead, we provide a personalised overview into the areas of network epidemiology that have seen the greatest progress in recent ...

Danon, Leon; House, Thomas; Jewell, Chris P; Keeling, Matt J; Roberts, Gareth O; Ross, Joshua V; Vernon, Matthew C

2010-01-01T23:59:59.000Z

247

CXC Receptor 1 and 2 and Neutrophil Elastase Inhibitors Alter Radiation-induced Lung Disease in the Mouse  

SciTech Connect

Purpose: We previously reported increased numbers of neutrophils to be associated with the development of the radiation-induced lung responses of alveolitis (pneumonitis) and fibrosis in mice. In the present study we investigated whether CXC receptor 1 and 2 antagonism with DF2156A, a small molecule inhibitor of neutrophil chemotaxis, or the neutrophil elastase inhibitor sivelestat decreases the lung response to irradiation. Methods and Materials: KK/HIJ mice received 14 Gy whole-thorax irradiation, and a subset of them received drug treatment 3 times per week from the day of irradiation until they were killed because of respiratory distress symptoms. Results: Irradiated mice receiving sivelestat survived 18% longer than did mice receiving radiation alone (73 vs 60 days for female mice, 91 vs 79 days for male mice), whereas postirradiation survival times did not differ between the group of mice receiving DF2156A and the radiation-only group. The numbers of neutrophils in lung tissue and in bronchoalveolar lavage fluid did not differ among groups of irradiated mice, but they significantly exceeded the levels in unirradiated control mice. The extent of alveolitis, assessed histologically, did not differ between irradiated mice treated with either drug and those receiving radiation alone, when assessed at the end of the experiment, but it was significantly reduced, as were the neutrophil measures, in sivelestat-treated mice at the common kill time of 60 days after irradiation. Mice treated with radiation and DF2156A developed significantly less fibrosis than did mice receiving radiation alone, and this difference was associated with decreased expression of interleukin-13 in lung tissue. Conclusions: We conclude that neutrophil elastase inhibition affects alveolitis and prolongs survival, whereas CXCR1/2 antagonism reduces radiation-induced fibrotic lung disease in mice without affecting the onset of distress.

Fox, Jessica [Department of Medicine and the Meakins-Christie Laboratories, McGill University, Montreal, Quebec (Canada)] [Department of Medicine and the Meakins-Christie Laboratories, McGill University, Montreal, Quebec (Canada); Haston, Christina K., E-mail: christina.haston@mcgill.ca [Department of Medicine and the Meakins-Christie Laboratories, McGill University, Montreal, Quebec (Canada)

2013-01-01T23:59:59.000Z

248

SU?E?T?413: Optimizing the Delivery of Intensity?Modulated Stereotactic Body Radiation Therapy to Lung Tumours Influenced by Respiratory Motion  

Science Journals Connector (OSTI)

Purpose: To quantify the interplay effect for various IMRT techniques used to deliver Stereotactic?Body Radiation Therapy(SBRT) to early?stage lungcancer. Methods: Five lungcancer patients who received SBRT were retrospectively planned (54Gy/3fx) on the average 4D?CT dataset with eight different IMRT techniques: three fixed?beam IMRT plans (simple step?and?shoot (S/S) complex S/S and sliding?window (S/W)) Tomotherapy plans using three different beam sizes (1cm 2.5cm and 5cm) and two Volumetric?Modulated Arc Therapy (VMAT) plans (one planned with Rapid Arc (Eclipse v8.9 Varian Medical Systems Palo Alto USA) and one planned with Smart Arc (Pinnacle v9.0 Philips Medical Systems Cleveland USA)). All treatment plans were calculated on a CT of the ArcCHECK phantom by Sun Nuclear (Gland Switzerland) that was mounted on the QUASAR Programmable Respiratory Motion Platform (Modus Medical Devices Inc. London Ontario). Each plan was delivered under the following motion conditions: 1) Static mode; 2) Sinusoidal mode (4s period) with S/I motion ranging from 5mm20mm peak?to?peak in 5 mm increments; 3) Real?patient waveforms ranging from 5mm30mm peak?to?peak. A standard 3%/3mm gamma analysis compared each delivery to their corresponding calculated plan. Results: All methods were acceptable on average (>90% points pass) up to 15mm peak?to?peak motion except for the Rapid Arc plan which had a significantly less pass rate (75.6+/?3.9%) than all other techniques (p<.02). Tomotherapy plans using either a 2.5cm beam (98.7+/?2.1%) or 5cm beam (96.8+/?3.5%) were still acceptable for motion up to 20 mm peak?to?peak. For irregular motion greater than 15mm only the VMAT techniques failed ((74.9+/?16.6)% for Rapid Arc and (89.3+/?8.9)% for Smart Arc on average. Conclusions: Interplay effect in SBRTdelivery was dependent on the IMRT technique for peak?to?peak motions greater than 15 mm. Tomotherapy was the least sensitive for motion up to 20mm. Rapid Arc was the most sensitive for motion greater than 15mm peak?to?peak.

S Gaede; N Hamelin; M Kline; S Goosheh; S Yartsev; J Chen

2011-01-01T23:59:59.000Z

249

Relationship between dental disease and radiation necrosis of the mandible  

SciTech Connect

Preirradiation panoramic radiographs of forty-six dentate patients were examined for the presence of significant dental disease. Evidence of a positive association between dental disease present before radiation therapy and subsequent necrosis of the mandible was found leading to a recommendation that significant disease be eradicated before irradiation of oral tissues. Considerable suffering results from bone necrosis, which can be reduced by careful and rational dental diagnosis and treatment.

Murray, C.G.; Daly, T.E.; Zimmerman, S.O.

1980-02-01T23:59:59.000Z

250

Global Health: Measuring the Global Burden of Disease  

Science Journals Connector (OSTI)

...effective and high-quality care to patients without knowing their diagnoses; likewise, for health systems to be effective, it is necessary to understand the key challenges in efforts to improve population health and how these challenges are changing. Before the early 1990s, there was no comprehensive... The burden that disease places on societies around the world is complex and changing as communicable diseases are replaced by noncommunicable diseases. This article summarizes these changes and the current burden.

Murray C.J.L.; Lopez A.D.

2013-08-01T23:59:59.000Z

251

ORISE Research Participation Programs at the Centers for Disease...  

NLE Websites -- All DOE Office Websites (Extended Search)

Research Participation Programs at The Centers for Disease Control and Prevention Oak Ridge Institute for Science and Education Home About the CDC About ORISE Current Research...

252

ORNL, UTGSM study compares structures of Huntington's disease...  

NLE Websites -- All DOE Office Websites (Extended Search)

ORNL, UTGSM study compares structures of Huntington's disease protein Researchers used neutron scattering experiments to clarify structural differences between the normal (left)...

253

Strategies of survival; lectures on population, disease, war, famine  

E-Print Network (OSTI)

Lectures on the theories of Malthus, and on disease, war and famine, including theories of McKeown, Adam Smith and Amartya Sen...

Macfarlane, Alan

2007-02-14T23:59:59.000Z

254

E-Print Network 3.0 - atherosclerotic cardiovascular disease...  

NLE Websites -- All DOE Office Websites (Extended Search)

the molecular Summary: .Riou@ujf-grenoble.fr > LMR and AB equally contributed to this work Abstract Cardiovascular diseases (CVD) are the leading... ; vulnerable coronary...

255

E-Print Network 3.0 - acute encephalitis syndrome Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

20 Environmental Health & Health & Disease Summary: Human Transport of Disease SARS The Cough Heard Round the World Severe Acute Respiratory Syndrome 2003 1... disease related...

256

Understanding verbal fluency in healthy aging, Alzheimers disease, and Parkinsons disease  

E-Print Network (OSTI)

McDowd, J., Hoffman, L., Rozek, E., Lyons, K., Pahwa, R., Burns, J. , & Kemper, S. (2011). Understanding verbal fluency in healthy aging, Alzheimers disease, and Parkinsons disease. Neuropsychologia, 25, 210-225. DOI: 10.1037/a0021531.... Publishers official version: http://dx.doi.org/10.1037/a0021531. Open Access version: http://kuscholarworks.ku.edu/dspace/. 1 P le a se n o te t h a t th is is a n a u th o r- p ro d u ce d P D F o f a n a rt ic le a cc ep te d f o r p...

McDowd, Joan; Hoffman, Lesa; Rozek, Ellen Kathryn; Lyons, Kelly E.; Pahwa, Rajesh; Burns, Jeffrey M.; Kemper, Susan

2011-01-01T23:59:59.000Z

257

Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patients  

SciTech Connect

Mitochondrial DNA (mtDNA) variants associated with Alzheimer disease (AD) and Parkinson disease (PD) were sought by restriction endonuclease analysis in a cohort of 71 late-onset Caucasian patients. A tRNA[sup Gln] gene variant at nucleotide pair (np) 4336 that altered a moderately conserved nucleotide was present in 9/173 (5.2%) of the patients surveyed but in only 0.7% of the general Caucasian controls. One of these patients harbored an additional novel 12S rRNA 5-nucleotide insertion at np 956-965, while a second had a missense variant at np 3397 that converted a highly conserved methionine to a valine. This latter mutation was also found in an independent AD + PD patient, as was a heteroplasmic 16S rRNA variant at np 3196. Additional studies will be required to determine the significance, if any, of these mutations. 122 refs., 4 figs., 2 tabs.

Shoffner, J.M.; Brown, M.D.; Torroni, A.; Lott, M.T.; Cabell, M.F.; Mirra, S.S.; Yang, C.C.; Gearing, M.; Salvo, R. (Emory Univ. School of Medicine, Atlanta, GA (United States)); Beal, M.F. (Harvard Medical School, Boston, MA (United States)) (and others)

1993-07-01T23:59:59.000Z

258

Using yeast to study neurodegenerative diseases : amyloid formation as a protective mechanism and a new Alzheimer's disease model  

E-Print Network (OSTI)

Numerous neurodegenerative diseases are pathologically characterized by idiosyncratic protein amyloid inclusions. Not surprisingly amyloid fibrils have long been proposed to be the toxic protein species in these neurodegenerative ...

Treusch, Sebastian

2011-01-01T23:59:59.000Z

259

Do changes in traditional coronary heart disease risk factors over time explain the association between socio-economic status and coronary heart disease?  

E-Print Network (OSTI)

case-control study. Heart 2009, Franks P, Tancredi DJ,status in coronary heart disease risk estimation. Ann Famstatus and coronary heart disease risk prediction. JAMA

Franks, Peter; Winters, Paul C; Tancredi, Daniel J; Fiscella, Kevin A

2011-01-01T23:59:59.000Z

260

Disease avoidance as a functional basis for stigmatization  

Science Journals Connector (OSTI)

...broadening of the model allows for stigmatization...specified to predict the precise similarities...we propose a model of disease-avoidance-based...following the outbreak of severe acute...disease risk model and its alternatives...2009 Amid swine flu outbreak, racism goes...

2011-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "respiratory disease orthopedic" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


261

Disease avoidance as a functional basis for stigmatization  

Science Journals Connector (OSTI)

...race and disease in the 20th century America. Lancet 367, 531-533...the nineteenth and twentieth centuries. Bull. Hist. Med. 44...and nonhandicapped boys in a camp setting. J. Spec. Ed. 8...disease identity in twentieth century America. Baltimore, MD...

2011-01-01T23:59:59.000Z

262

Salivary Microbiota and Metabolome Associated with Celiac Disease  

Science Journals Connector (OSTI)

...disease (CD) under a gluten-free diet (treated celiac disease...ratios (5, 9). The gluten-free diet (GFD) is effective...properties in relation to gluten free diet in children with celiac...metabolome of children with autism and pervasive developmental...

Ruggiero Francavilla; Danilo Ercolini; Maria Piccolo; Lucia Vannini; Sonya Siragusa; Francesca De Filippis; Ilaria De Pasquale; Raffaella Di Cagno; Michele Di Toma; Giorgia Gozzi; Diana I. Serrazanetti; Maria De Angelis; Marco Gobbetti

2014-03-21T23:59:59.000Z

263

Affordable System for Rapid Detection and Mitigation of Emerging Diseases  

Science Journals Connector (OSTI)

South and South-East Asian countries are currently in the midst of a new epidemic of Dengue Fever. This paper presents disease surveillance systems in Sri Lanka and India, monitoring a handful of communicable diseases termed as notifiable. These systems ... Keywords: Alerting, Biosurveillance, Data Mining, Epidemiology, Interoperability, Mhealth, Spatio-Temporal Analysis

Nuwan Waidyanatha, Artur Dubrawski, Ganesan M., Gordon Gow

2011-01-01T23:59:59.000Z

264

Chronic Beryllium Disease Prevention Program (10 CFR 850)  

Energy.gov (U.S. Department of Energy (DOE))

The DOE established a chronic beryllium disease prevention program (CBDPP) to reduce the number of workers currently exposed to beryllium in the course of their work at DOE facilities managed by DOE or its contractors, minimize the levels of, and potential for, exposure to beryllium, and establish medical surveillance requirements to ensure early detection of the disease.

265

Inherited Neuronal Ion Channelopathies: New Windows on Complex Neurological Diseases  

E-Print Network (OSTI)

cause of these diseases. Key words: sodium channels; calcium channels; epilepsy; migraine; pain; genetic diseases Introduction Voltage-gated sodium and calcium channels are closely related members of the ion­IV), which each consists of six -helical trans- membrane segments (S1­S6) and a pore loop connecting S5 and S

Meisler, Miriam

266

CAMB 630 Topics in Human Genetics and Disease Course Directors  

E-Print Network (OSTI)

on the foundations of the Human Genome Project and parallel efforts in model organisms, research in human genetics in Human Genetics and Disease: I. Genome architecture and instability (Spinner) Chromosome specific variation II. Human genomic variation and disease (Devoto) History and substructure of the human population

Plotkin, Joshua B.

267

Arsenic in drinking water Increases mortality from cardiovascular disease  

E-Print Network (OSTI)

Arsenic in drinking water Increases mortality from cardiovascular disease Allan H Smith professor of inorganic arsenic in drinking water causes cancer of the skin, bladder, lung, liver, and kidney.1 2 Mounting of a link between cardiovascular disease and arsenic in drinking water came in 1980 from Antofagasta, Chile

California at Berkeley, University of

268

Status Report, Department of Energy's Chronic Beryllium Disease Prevention  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Status Report, Department of Energy's Chronic Beryllium Disease Status Report, Department of Energy's Chronic Beryllium Disease Prevention Program - February 2006 Status Report, Department of Energy's Chronic Beryllium Disease Prevention Program - February 2006 February 2006 Report on Implementation of 10 CFR Part 850, Chronic Beryllium Disease Prevention Program During calendar year 2005, the Office of Independent Oversight, within the Office of Security and Safety Performance Assurance, evaluated the effectiveness of U.S. Department of Energy (DOE) chronic beryllium disease protection programs (CBDPPs) at five sites as part of regularly scheduled inspections. These reviews focused on site programs for ensuring that workers are protected in accordance with the requirements of 10 CFR 850. This report summarizes the observations, insights, and lessons learned from

269

Status Report, Department of Energy's Chronic Beryllium Disease Prevention  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Status Report, Department of Energy's Chronic Beryllium Disease Status Report, Department of Energy's Chronic Beryllium Disease Prevention Program - February 2006 Status Report, Department of Energy's Chronic Beryllium Disease Prevention Program - February 2006 February 2006 Report on Implementation of 10 CFR Part 850, Chronic Beryllium Disease Prevention Program During calendar year 2005, the Office of Independent Oversight, within the Office of Security and Safety Performance Assurance, evaluated the effectiveness of U.S. Department of Energy (DOE) chronic beryllium disease protection programs (CBDPPs) at five sites as part of regularly scheduled inspections. These reviews focused on site programs for ensuring that workers are protected in accordance with the requirements of 10 CFR 850. This report summarizes the observations, insights, and lessons learned from

270

Proteins' Amazing Origami Powers: Insight for Potential Disease Treatments  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Proteins' Amazing Origami Powers: Insight for Potential Disease Proteins' Amazing Origami Powers: Insight for Potential Disease Treatments Proteins' Amazing Origami Powers: Insight for Potential Disease Treatments October 4, 2011 - 12:46pm Addthis This is a visualization of drug molecules ("parade day-like balloons") in a simulated attack of the ribbon-like protein fibrils that are believed to be the cause of Alzheimer’s disease. Click here to see more amazing supercomputer simulations. | Image courtesy of ORNL. This is a visualization of drug molecules ("parade day-like balloons") in a simulated attack of the ribbon-like protein fibrils that are believed to be the cause of Alzheimer's disease. Click here to see more amazing

271

Evaluation of Biomimetic and Alloy-based Materials for Orthopedic Applications  

E-Print Network (OSTI)

then polished to a 0.3 ?m finish using silicon carbide paper followed by alumina colloidal powder on all sides. 2.3.2. Polyelectrolyte coating fabrication Two sets of homogenized NiMnSn samples were coated using layer-by-layer assembly via dip... in the presence of alloy specimens or metal controls (Ni, Mn, Sn) for a period of 14 days, as described in the following sections. 2.3.3.1. Polymer synthesis PEGDA was prepared by combining 0.1 mmol/mL dry PEG (6 kDa; Sigma), 0.4 mmol/mL acryloyl...

Guiza-Arguello, Viviana R.

2013-07-17T23:59:59.000Z

272

An extensive analysis of modified nanotube surfaces for next-generation orthopedic implants  

E-Print Network (OSTI)

nanotubes for improved dye-sensitized solar cells. Journal of Renewable and Sustainable Energy.energy of the Ti-O bond (323 kJ/mol) to the fact that TiO 2 nanotubes

Frandsen, Christine Jeanette

2012-01-01T23:59:59.000Z

273

Pseudo-Outbreak of Lecanicillium and Acremonium Species in Orthopedic Surgery Patients  

Science Journals Connector (OSTI)

...flooring (3), the used laboratory and operating suite HVAC air filters, and unused specimen collection cups (3) were also...samples in various locations in the hospital, and air filters in the operating room and laboratories did not yield...

Carolyn O. S. Neal; Eszter Deak; Loretta S. Chang; Heather Gilmartin; Lalitha Gade; Maho Imanishi; Connie Price; Mary E. Brandt; Tom Chiller; S. Arunmozhi Balajee

2012-09-26T23:59:59.000Z

274

SmartCast - Novel Textile Sensors for Embedded Pressure Sensing of Orthopedic Casts  

E-Print Network (OSTI)

>. [4] Buechley, Leah. "LilyPad Arduino: How an Open SourceSD Card by calling the Arduino * SD Card library functionson return code from Arduino library * Inputs: * Outputs:

Danilovic, Andrew

2013-01-01T23:59:59.000Z

275

Ebola Virus Disease The current outbreak of Ebola Virus Disease (EVD) in West Africa has involved the  

E-Print Network (OSTI)

Ebola Virus Disease The current outbreak of Ebola Virus Disease (EVD) in West Africa has involved the countries of Sierra Leone, Liberia, Guinea, and Nigeria. This has become the largest outbreak of Ebola want to make sure you have the most accurate information about this illness. What is Ebola Virus

MacAdam, Keith

276

Foundation for the Support of Research on Alzheimer's Disease and other Neurodegenerative Diseases Synapsis Foundation, Fabrikstrasse 50, CH-8031 Zrich  

E-Print Network (OSTI)

Foundation for the Support of Research on Alzheimer's Disease and other Neurodegenerative Diseases Synapsis Foundation, Fabrikstrasse 50, CH-8031 Zürich Tel. +41 (0)44 271 35 11, Fax +41 (0)44 271 35 12 Submission Deadline 31st August, 2011 SYNAPSIS FOUNDATION with its research programme "Alzheimer Research

Richner, Heinz

277

Development and Characterization of a Multiplexed RT-PCR Species Specific Assay for Bovine and one for Porcine Foot-and-Mouth Disease Virus Rule-Out Supplemental Materials  

SciTech Connect

Lawrence Livermore National Laboratory (LLNL), in collaboration with the Department of Homeland Security (DHS) and the United States Department of Agriculture (USDA), Animal and Plant Health Inspection Services (APHIS) has developed advanced rapid diagnostics that may be used within the National Animal Health Laboratory Network (NAHLN), the National Veterinary Services Laboratory (Ames, Iowa) and the Plum Island Animal Disease Center (PIADC). This effort has the potential to improve our nation's ability to discriminate between foreign animal diseases and those that are endemic using a single assay, thereby increasing our ability to protect animal populations of high economic importance in the United States. Under 2005 DHS funding we have developed multiplexed (MUX) nucleic-acid-based PCR assays that combine foot-and-mouth disease virus (FMDV) detection with rule-out tests for two other foreign animal diseases Vesicular Exanthema of Swine (VESV) and Swine Vesicular Disease (SVD) and four other domestic viral diseases Bovine Viral Diarrhea Virus (BVDV), Bovine Herpes Virus 1 (BHV-1 or Infectious Bovine Rhinotracheitus IBR), Bluetongue virus (BTV) and Parapox virus complex (which includes Bovine Papular Stomatitis Virus BPSV, Orf of sheep, and Pseudocowpox). Under 2006 funding we have developed a Multiplexed PCR [MUX] porcine assay for detection of FMDV with rule out tests for VESV and SVD foreign animal diseases in addition to one other domestic vesicular animal disease vesicular stomatitis virus (VSV) and one domestic animal disease of swine porcine reproductive and respiratory syndrome (PRRS). We have also developed a MUX bovine assay for detection of FMDV with rule out tests for the two bovine foreign animal diseases malignant catarrhal fever (MCF), rinderpest virus (RPV) and the domestic diseases vesicular stomatitis virus (VSV), bovine viral diarrhea virus (BVDV), infectious bovine rhinotracheitus virus (BHV-1), bluetongue virus (BTV), and the Parapox viruses which are of two bovine types bovine papular stomatitis virus (BPSV) and psuedocowpox (PCP). This document provides details of signature generation, evaluation, and testing, as well as the specific methods and materials used. A condensed summary of the development, testing and performance of the multiplexed assay panel was presented in a 126 page separate document, entitled 'Development and Characterization of A Multiplexed RT-PCR Species Specific Assay for Bovine and one for Porcine Foot-and-Mouth Disease Virus Rule-Out'. This supplemental document provides additional details of large amount of data collected for signature generation, evaluation, and testing, as well as the specific methods and materials used for all steps in the assay development and utilization processes. In contrast to last years effort, the development of the bovine and porcine panels is pending additional work to complete analytical characterization of FMDV, VESV, VSV, SVD, RPV and MCF. The signature screening process and final panel composition impacts this effort. The unique challenge presented this year was having strict predecessor limitations in completing characterization, where efforts at LLNL must preceed efforts at PIADC, such challenges were alleviated in the 2006 reporting by having characterization data from the interlaboratory comparison and at Plum Island under AgDDAP project. We will present an addendum at a later date with additional data on the characterization of the porcine and bovine multiplex assays when that data is available.

Smith, S; Danganan, L; Tammero, L; Lenhoff, R; Naraghi-arani, P; Hindson, B

2007-08-06T23:59:59.000Z

278

Particulate matter and heart disease: Evidence from epidemiological studies  

SciTech Connect

The association between particulate matter and heart disease was noted in the mid-nineties of last century when the epidemiological evidence for an association between air pollution and hospital admissions due to cardiovascular disease accumulated and first hypotheses regarding the pathomechanism were formulated. Nowadays, epidemiological studies have demonstrated coherent associations between daily changes in concentrations of ambient particles and cardiovascular disease mortality, hospital admission, disease exacerbation in patients with cardiovascular disease and early physiological responses in healthy individuals consistent with a risk factor profile deterioration. In addition, evidence was found that annual average PM{sub 2.5} exposures are associated with increased risks for mortality caused by ischemic heart disease and dysrhythmia. Thereby, evidence is suggesting not only a short-term exacerbation of cardiovascular disease by ambient particle concentrations but also a potential role of particles in defining patients' vulnerability to acute coronary events. While this concept is consistent with the current understanding of the factors defining patients' vulnerability, the mechanisms and the time-scales on which the particle-induced vulnerability might operate are unknown.

Peters, Annette [GSF-National Research Center for Environment and Health, Institute of Epidemiology, Ingolstaedter Landstr. 1, 85764 Neuherberg (Germany)]. E-mail: peters@gsf.de

2005-09-01T23:59:59.000Z

279

Medical Progress: Tick-Borne Diseases in the United States  

Science Journals Connector (OSTI)

...reservoirs for Colorado tick fever, but other rodents and mammals, such as rabbits and deer, may be infected. Most human infections are acquired from tick bites, but the virus has been transmitted by blood transfusion. The disease occurs in mountainous regions of 11 western states: Colorado, Utah, South... In the United States, more vector-borne diseases are transmitted by ticks than by any other agent1. During the past 20 years, tick-borne diseases have taken on increased importance as humans have moved into rural areas and increased their recreational ...

Spach D.H.; Liles W.C.; Campbell G.L.

1993-09-23T23:59:59.000Z

280

Counting small RNA in disease-causing organisms  

NLE Websites -- All DOE Office Websites (Extended Search)

Counting small RNA in disease-causing organisms Counting small RNA in disease-causing organisms Counting small RNA in disease-causing organisms Los Alamos researchers demonstrated improved technical methods capable of directly counting small RNA molecules in pathogenic (disease-causing) bacteria. June 17, 2013 Artist's concept of the fluorescence labeling and detection of small RNA in pathogenic bacteria. Artist's concept of the fluorescence labeling and detection of small RNA in pathogenic bacteria. The new technique reduced the number of false positives, which improved the accuracy of the count statistics, and it significantly reduced the image processing time. Small molecules of RNA (tens to hundreds of nucleotides in length) play a key regulatory role in bacteria. Due to their small size, directly

Note: This page contains sample records for the topic "respiratory disease orthopedic" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


281

Retinal Diseases: Age-Related Macular Degeneration and Retinitis Pigmentosa  

NLE Websites -- All DOE Office Websites (Extended Search)

Retinal Diseases: Age-Related Macular Degeneration and Retinitis Pigmentosa Retinal Diseases: Age-Related Macular Degeneration and Retinitis Pigmentosa Age-related macular degeneration (AMD) is an eye disease primarily affecting the central vision regions in people age 60 and older. According to the Macular Degeneration Research Fund, a case of AMD is diagnosed in the United States every 3 minutes. Each year, 1.2 million of the estimated 12 million people with AMD will suffer severe vision loss. Patients with AMD have dark areas in their vision caused by fluid leakage or bleeding in the macula, the center of the retina that produces the sharpest vision. The brain initially compensates for these dark patches. Early cellular dysfunction or spotting in the macula may go undetected until the disease is in advanced stages.

282

Current drivers and future directions of global livestock disease dynamics  

Science Journals Connector (OSTI)

...demand models other than...and HPAI outbreaks or threats...ability to predict changes is...Endemic disease outbreaks Greater private...and other models Livestock Revolution...2005 ) Models of foot-and-mouth...Web data predict flu . Nature...

Brian D. Perry; Delia Grace; Keith Sones

2013-01-01T23:59:59.000Z

283

Ebola virus disease: an update for anesthesiologists and intensivists  

Science Journals Connector (OSTI)

Ebola virus disease (EVD) is a viral hemorrhagic fever that is highly transmissible and all too often rapidly fatal. Recent outbreaks in West Africa reveal that this infection has the potential to be transmitt...

Duane J. Funk MD; Anand Kumar MD

2014-11-01T23:59:59.000Z

284

An Analysis of some Necrotic Virus Diseases of the Potato  

Science Journals Connector (OSTI)

1 June 1932 research-article An Analysis of some Necrotic Virus Diseases of the Potato Redcliffe N. Salaman F. C. Bawden The Royal Society is collaborating with JSTOR to digitize, preserve, and extend access to...

1932-01-01T23:59:59.000Z

285

Crinkle "A," an Infectious Disease of the Potato  

Science Journals Connector (OSTI)

14 January 1930 research-article Crinkle "A," an Infectious Disease of the Potato Redcliffe N. Salaman The Royal Society is collaborating with JSTOR to digitize, preserve, and extend access to Proceedings of...

1930-01-01T23:59:59.000Z

286

Brief Report: Recombinant Osteoprotegerin for Juvenile Paget's Disease  

Science Journals Connector (OSTI)

The change in the size and shape of the skeleton during growth and its renewal during adult life depend on the closely coordinated activity of bone-resorbing cells (osteoclasts) and bone-forming cells (osteoblasts). The receptor activator of nuclear factor-?B (RANK) ligand (RANKL)osteoprotegerinRANK... Juvenile Paget's disease, a genetic bone disease characterized by accelerated bone turnover, results from inactivating mutations in the gene encoding osteoprotegerin, a key regulator of osteoclastogenesis. The authors investigated the effects of recombinant osteoprotegerin in two adult siblings with juvenile Paget's disease. After 15 months, radial bone mass had increased, skeletal bisphosphonate retention had decreased, and there was radiographic improvement. Osteoprotegerin may be therapeutic in juvenile Paget's disease.

Cundy T.Davidson J.Rutland M.D.Stewart C.DePaoli A.M.

2005-09-01T23:59:59.000Z

287

Correlates of Hippocampal Neuron Number in Alzheimer's Disease and Ischemic  

E-Print Network (OSTI)

White, MD,6 and Helena C. Chui, MD7 The cornu ammonis 1 region of the hippocampus (CA1) sector-vessel disease, and leukoariosis.1 The cornu ammonis 1 region of the hippocampus (CA1) sector of hippocampus

California at Davis, University of

288

Infectious diseases of animals and plants: an interdisciplinary approach  

Science Journals Connector (OSTI)

...interdisciplinary approach to studying the management of infectious...and natural science research...interdisciplinary approach, combining...and social sciences, to disease management. Firstly...interdisciplinary approach to studying the management of infectious...and natural science research...

2011-01-01T23:59:59.000Z

289

Global Change and Human Vulnerability to Vector-Borne Diseases  

Science Journals Connector (OSTI)

...climate change scenarios because solutions require the design of strategies...range of circumstances. Natural solutions for vector-borne diseases are...gas from the ground into the air by burning fossil fuels. The global consumption juggernaut...

Robert W. Sutherst

2004-01-01T23:59:59.000Z

290

Global Change and Human Vulnerability to Vector-Borne Diseases  

Science Journals Connector (OSTI)

...diseases depends on three capacities: effective...constraints (244) or sustainability and robustness (309...http://www.sustainability.com/philosophy...the key principles of sustainability are to think long-term...to grave, forms one pillar of any information...

Robert W. Sutherst

2004-01-01T23:59:59.000Z

291

What college students should know about Meningococcal Disease  

E-Print Network (OSTI)

. Sometimes these bacteria invade the body to infect the lining of the brain (causing meningitis. Brain damage, hearing loss, loss of limbs, or kidney failure can also occur. Meningococcal disease

Wisconsin at Madison, University of

292

Preventing Alzheimer's disease by means of natural selection  

Science Journals Connector (OSTI)

...Alzheimer's disease|natural selection|neuroenergetics...context of the amyloid cascade model. These features...solids, liquids and gases). Thermodynamic entropy...process, thus turning natural selection to our patients...matter-solid, liquid or gas. The quantity describes...

2015-01-01T23:59:59.000Z

293

Brain Iron as an Early Predictor of Alzheimer's Disease | Advanced...  

NLE Websites -- All DOE Office Websites (Extended Search)

| 2004 | 2003 | 2002 2001 | 2000 | 1998 | Subscribe to APS Science Highlights rss feed Brain Iron as an Early Predictor of Alzheimer's Disease JUNE 15, 2011 Bookmark and Share (A)...

294

Collaborative Help in Chronic Disease Management: Supporting Individualized Problems  

E-Print Network (OSTI)

Collaborative Help in Chronic Disease Management: Supporting Individualized Problems ABSTRACT for how diabetes patient support groups help one another find individualized strategies for managing diabetes community, and interviews, we found several help interactions that are critical in helping

Anderson, Richard

295

A biophysical marker of severity in sickle cell disease  

E-Print Network (OSTI)

The search for predictive indicators of disease has largely focused on molecular markers. However, biophysical markers, which can integrate multiple pathways, may provide a more global picture of pathophysiology. Sickle ...

Mahadevan, L.

296

Involvement of interleukin-4 and -10 in inflammatory bowel disease  

Science Journals Connector (OSTI)

The pathogenesis of ulcerative colitis (UC) and Crohn's disease (CD) may be associated with a decreased production of cytokines suppressing macrophage and T-cell functions: interleukins (IL) -4 and IL-10. Seru...

Dr. O. H. Nielsen MD; DMSc; T. Kppen MSc

1996-09-01T23:59:59.000Z

297

Status Report, Department of Energy's Chronic Beryllium Disease...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

of 10 C.F.R. Part 850, Chronic Beryllium Disease Prevention Program, at the Department of Energy (DOE). The report is based on the results of evaluations of the effectiveness of...

298

The Role of HIV-1 Proteins in Alzheimer's Disease Pathology.  

E-Print Network (OSTI)

??Prevalence of HIV-associated cognitive impairment is rising, the worst form of which is HIV-associated dementia (HAD). The disease is fuiled by a chronic innate type (more)

Giunta, Brian Nelson

2011-01-01T23:59:59.000Z

299

Ruptured sinus of valsalva masquerading as rheumatic heart disease  

Science Journals Connector (OSTI)

Ruptured sinus of Valsalva is a rare lesion in pediatric age group. We are reporting a twelve year old child with hyperdynamic circulation being diagnosed and treated as Rheumatic heart disease.

Mukesh Kumar Beniwal; Dinesh Kumar Yadav; Pankaj Kumar Gupta

2012-10-01T23:59:59.000Z

300

artery disease involving: Topics by E-print Network  

NLE Websites -- All DOE Office Websites (Extended Search)

E. Lundquist; James P. Ward 72 Association of Common Polymorphisms in GLUT9 Gene with Gout but Not with Coronary Artery Disease in a Large Case-Control Study CiteSeer Summary:...

Note: This page contains sample records for the topic "respiratory disease orthopedic" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


301

Striatal origin of the pathologic beta oscillations in Parkinson's disease  

E-Print Network (OSTI)

Enhanced oscillations at beta frequencies (830 Hz) are a signature neural dynamic pathology in the basal ganglia and cortex of Parkinson's disease patients. The mechanisms underlying these pathological beta oscillations ...

Boyden, Edward Stuart

302

Red Blood cell Alloimmunization in Sickle Cell Disease: Pathophysiology, Risk Factors, and Transfusion Management  

E-Print Network (OSTI)

1 Red Blood cell Alloimmunization in Sickle Cell Disease: Pathophysiology, Risk Factors; email: france.noizat-pirenne@efs.sante.fr Keywords: sickle cell disease, alloimmunization, DHTR with sickle cell disease (SCD). Transfusions can lead to erythrocyte alloimmunization, however, with serious

Boyer, Edmond

303

Randomized Trial of Posaconazole and Benznidazole for Chronic Chagas' Disease  

Science Journals Connector (OSTI)

...partially susceptible T. cruzi strains, whereas only 76% were cured with benznidazole. In the model of chronic Chagas' disease, the differences were even greater: posaconazole was associated with cure rates of up to 60% in animals infected with susceptible and partially susceptible T. cruzi strains, whereas... There are limited treatment options for Trypanosoma cruzei infection, or Chagas' disease. Preclinical data had suggested that posaconazole might be an effective therapy. In this randomized trial, posaconazole monotherapy was found not to be effective.

Molina I.; Gmez i Prat J.; Salvador F.

2014-05-15T23:59:59.000Z

304

Effects of Vaccination on Invasive Pneumococcal Disease in South Africa  

Science Journals Connector (OSTI)

...through December 2012. Duplicate isolates cultured within 21 days after the initial positive culture were excluded. Serotyping and Susceptibility Testing. Pneumococci were serotyped with the use of the quellung reaction (Statens Serum Institut). Serotype 6C was distinguished from 6A throughout. We determined... Invasive pneumococcal disease is an important cause of severe illness. In South Africa, a national program to vaccinate children with the conjugated pneumococcal vaccine resulted in a substantial decline in invasive pneumococcal disease countrywide, including in adults.

von Gottberg A.; de Gouveia L.; Tempia S.

2014-11-13T23:59:59.000Z

305

Global Health: Behavioral and Dietary Risk Factors for Noncommunicable Diseases  

Science Journals Connector (OSTI)

...affected population health in the past or how they may do so in the future. In this article, we summarize the available data on trends in selected behavioral and dietary risk factors for noncommunicable diseases and examine the effects they have had, or may have in the future, on the health of populations... This review in the Global Health series focuses on the role of smoking, alcohol, and obesity in the burden of noncommunicable disease.

Ezzati M.; Riboli E.

2013-09-05T23:59:59.000Z

306

When Diseases Disappear The Case of Familial Dysautonomia  

Science Journals Connector (OSTI)

...dysautonomia disappears, the historian Susan Lindee notes, a series of social and technological innovations will have made an invisible disease visible and then invisible once more. But it would be wrong to dismiss the condition as a 60-year-old problem that modern medicine eventually "fixed." For... The incidence of familial dysautonomia has decreased precipitously since population screening began in 2001. Dr. Barron Lerner writes that the potential disappearance of new cases of a disease raises profound questions.

Lerner B.H.

2009-10-22T23:59:59.000Z

307

Effect of Insulators on the Expression of betaAS3 in Lentiviral Gene Therapy for Sickle Cell Disease  

E-Print Network (OSTI)

al. (2001). Correction of sickle cell disease in transgenicto human bone marrow for sickle cell disease. Journal ofal. (2011). Correction of sickle cell disease in adult mice

Wherley, Jennifer Patricia

2013-01-01T23:59:59.000Z

308

E-Print Network 3.0 - agents causing diseases Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

disease is an inflammatory disease caused by a bacterium transmitted by ticks (small bloodsucking... that scientists think may transmit Ebola, a usually fatal ... Source:...

309

E-Print Network 3.0 - alzheimers disease neuroimaging Sample...  

NLE Websites -- All DOE Office Websites (Extended Search)

Disease... on NIA and ADEAR Websites...7 Alzheimer's Disease Education & Referral Center 2003 New CHID Resources... to examine how brains change as mild cognitive...

310

E-Print Network 3.0 - alzheimer disease human Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

Disease... on NIA and ADEAR Websites...7 Alzheimer's Disease Education & Referral Center 2003 New CHID Resources... to examine how brains change as mild cognitive...

311

E-Print Network 3.0 - asymptomatic gallstone disease Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

-ray confirmed Graves' DiseaseHyperthyroidism Hypothyroidism Thyroid nodule (benign) Gout SLE (systemic lupus... other benign breast disease Confirmed by breast biopsy?...

312

E-Print Network 3.0 - atypical vogt-koyanagi-harada disease Sample...  

NLE Websites -- All DOE Office Websites (Extended Search)

differences in size, form, flower, fruit, foliage, and disease resistant... in the trade; these vary greatly in their aesthetic, size and shape, and disease resistance...

313

E-Print Network 3.0 - atypical kawasaki disease Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

differences in size, form, flower, fruit, foliage, and disease resistant... in the trade; these vary greatly in their aesthetic, size and shape, and disease resistance...

314

E-Print Network 3.0 - acalculous gallbladder disease Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

disease", and is in the OBO namespace mixed disease ontology. It is ... Source: Shapiro, Stuart C. - Department of Computer Science and Engineering, State University of...

315

E-Print Network 3.0 - alveolar hydatid disease Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

Hydatid disease (echinococcosis) is due to infestation with cysts (metacestodes... . Poulin The Veterinary Journal 184 (2010) 9-13 12;hydatid disease may be more vulnerable to...

316

E-Print Network 3.0 - alzheimers disease brain Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

brain Search Powered by Explorit Topic List Advanced Search Sample search results for: alzheimers disease brain Page: << < 1 2 3 4 5 > >> 1 Understanding Alzheimer's Disease...

317

E-Print Network 3.0 - allergic lung disease Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

64 years of age who has a long- term health problem such as: heart disease lung disease sickle cell... Statements are available in Spanish and other languages. See...

318

E-Print Network 3.0 - animal disease outbreaks Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

Sample search results for: animal disease outbreaks Page: << < 1 2 3 4 5 > >> 1 Economic Consideration of Mitigation of Foreign Animal Disease Introduction * Summary:...

319

E-Print Network 3.0 - addison disease Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

and the Transmission of Infectious Diseases Summary: Tropical Environments, Human Activities, and the Transmission of Infectious Diseases LISA... host-pathogen interactions;...

320

E-Print Network 3.0 - atherosclerotic heart disease Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

heart disease Search Powered by Explorit Topic List Advanced Search Sample search results for: atherosclerotic heart disease Page: << < 1 2 3 4 5 > >> 1 Stent's unique nature may...

Note: This page contains sample records for the topic "respiratory disease orthopedic" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
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to obtain the most current and comprehensive results.


321

E-Print Network 3.0 - acute diarrheal disease Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

fever Diarrheal disease caused by a parasite... Human Transport of Disease SARS The Cough Heard Round the World Severe ... Source: Otter, Ryan R. - Department of Biology,...

322

E-Print Network 3.0 - activity disease characteristics Sample...  

NLE Websites -- All DOE Office Websites (Extended Search)

of the summer. Symptoms and Disease Characteristics From a distance, the symptoms... Patch Necrotic Ring Spot Rhizoctonia Large Patch Yellow Patch Turfgrass Disease Profiles...

323

E-Print Network 3.0 - anthracnose disease caused Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

and Ecology 35 Turfgrass Disease Profiles Purdue extension Summary: that cause brown patch and the Rhizoctonia large patch of zoysia grass (for more on these diseases, see......

324

Rheumatic Heart Disease and Beta-hemolytic Streptococci in Salvador, Brazil: A Study of Slum Health  

E-Print Network (OSTI)

rheumatic fever and rheumatic heart disease in Africa. S Afrthe chain that links the heart to the throat? Lancet Infectchildren with rheumatic heart disease. J Thorac Cardiovasc

Tartof, Sara Yee

2010-01-01T23:59:59.000Z

325

MRI Study on Maple Syrup Urine Disease via the LONI Pipeline With the creation of large image datasets for quantitative disease classification and diagnosis, like the Alzheimer's Disease  

E-Print Network (OSTI)

MRI Study on Maple Syrup Urine Disease via the LONI Pipeline Overview: With the creation of large pipeline implementation. Given this need, software tools like STAMPS (http://www.ncbi.nlm.nih.gov/pubmed/19346025) and the LONI Pipeline (http://pipeline.loni.ucla.edu/) were developed. These tools integrate

Bjørnstad, Ottar Nordal

326

Chapter 18 - Epigenetic Aberrations in Human Allergic Diseases  

Science Journals Connector (OSTI)

The epidemic rise in childhood allergic diseases is clear evidence that the developing immune system is highly vulnerable to modern environmental change. Together with observed presymptomatic differences in immune functions at birth, this suggests that environmental exposures during pregnancy are critical in determining the allergic risk of the offspring. A range of intrauterine exposures such as maternal dietary factors, exposure to microbes, pollutants, and maternal smoking are implicated in fetal immune programming and the risk of allergic diseases. Concepts of epigenetic modulation of gene expression now provide a mechanistic link for these complex early geneenvironmental interactions which appear to alter subsequent disease predisposition and potential heritability of disease risk across generations. As such, epigenetic changes provide a novel framework to explain the exponential rise in the prevalence of allergic diseases and other immune disorders within several generations. This is now supported by preliminary evidence that specific intrauterine exposures are associated with epigenetic changes in the expression of genes linked with either immune programming or an allergic phenotype in the offspring. Moreover, there are now examples of how these specific epigenetic effects can be passed on to subsequent generations. This new frontier provides not only novel insights into the understanding of complex immune diseases but also offers new opportunities to explore environmental strategies that can curb or even reverse the allergy epidemic through safe and effective reprogramming of gene expression during early development. While this possibility might now only appear as a distant horizon, the inherent epigenetic plasticity and observed capacity for intergenerational changes in disease predisposition offer great hope.

Manori Amarasekera; David Martino; Meri K. Tulic; Richard Saffery; Susan Prescott

2012-01-01T23:59:59.000Z

327

Bush Administration to Expand Beryllium Disease Screening Program |  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Bush Administration to Expand Beryllium Disease Screening Program Bush Administration to Expand Beryllium Disease Screening Program Bush Administration to Expand Beryllium Disease Screening Program February 23, 2005 - 10:27am Addthis Former employees of DOE vendors eligible for free screening WASHINGTON, DC - U.S. Secretary of Energy Samuel W. Bodman today announced the Department of Energy (DOE) will expand a beryllium screening program to include former employees of now-defunct DOE beryllium vendor companies across the country. Beryllium is a component used in nuclear weapons built by the Department of Energy. "Through no fault of their own, these Cold Warriors were left out in the cold when their former employers went out of business. By expanding this screening program, President Bush and the Department of Energy honor these

328

Title 10 CFR Part 850, Chronic Beryllium Disease Prevention Program  

NLE Websites -- All DOE Office Websites (Extended Search)

Wednesday Wednesday December 8, 1999 Part III Department of Energy 10 CFR Part 850 Chronic Beryllium Disease Prevention Program; Final Rule VerDate 29-OCT-99 10:58 Dec 07, 1999 Jkt 190000 PO 00000 Frm 00001 Fmt 4717 Sfmt 4717 E:\FR\FM\A08DE0.189 pfrm04 PsN: 08DER3 68854 Federal Register / Vol. 64, No. 235 / Wednesday, December 8, 1999 / Rules and Regulations DEPARTMENT OF ENERGY 10 CFR Part 850 [Docket No. EH-RM-98-BRYLM] RIN 1901-AA75 Chronic Beryllium Disease Prevention Program AGENCY: Office of Environment, Safety and Health, Department of Energy. ACTION: Final rule. SUMMARY: The Department of Energy (DOE) is today publishing a final rule to establish a chronic beryllium disease prevention program (CBDPP) to reduce the number of workers currently exposed to beryllium in the course of their work at DOE facilities managed by

329

Laser mass spectrometry for DNA sequencing, disease diagnosis, and fingerprinting  

SciTech Connect

Since laser mass spectrometry has the potential for achieving very fast DNA analysis, the authors recently applied it to DNA sequencing, DNA typing for fingerprinting, and DNA screening for disease diagnosis. Two different approaches for sequencing DNA have been successfully demonstrated. One is to sequence DNA with DNA ladders produced from Snager`s enzymatic method. The other is to do direct sequencing without DNA ladders. The need for quick DNA typing for identification purposes is critical for forensic application. The preliminary results indicate laser mass spectrometry can possibly be used for rapid DNA fingerprinting applications at a much lower cost than gel electrophoresis. Population screening for certain genetic disease can be a very efficient step to reducing medical costs through prevention. Since laser mass spectrometry can provide very fast DNA analysis, the authors applied laser mass spectrometry to disease diagnosis. Clinical samples with both base deletion and point mutation have been tested with complete success.

Winston Chen, C.H.; Taranenko, N.I.; Zhu, Y.F.; Chung, C.N.; Allman, S.L.

1997-03-01T23:59:59.000Z

330

Investigation of saliva of patients with periodontal disease using NAA  

SciTech Connect

In this study the non-stimulated whole saliva of 26 healthy subjects (mean age 33.9 {+-} 11.0 years, range: 26 to 49 years) and 11 patients with periodontal disease (mean age 41.7 {+-} 11.5 years; range 29 to 55 years) was investigated using Neutron Activation Analysis (NAA) technique. The samples were obtained from donors at Sao Paulo city (Brazil). The analyses were performed in the nuclear reactor IEA-R1 (3.5-4.5MW, pool type) at IPEN/CNEN-SP (Brazil). Considerable changes in Ca and S saliva's level were identified in patients with periodontal disease suggesting they can be used as monitors of periodontal diseases.

Zamboni, C. B.; Metairon, S.; Medeiros, I. M. M. A. [Instituto de Pesquisas Energeticas e Nucleares, IPEN - CNEN/SP Av. Professor Lineu Prestes 2242- 05508-000 Sao Paulo, SP (Brazil); Lewgoy, H. R. [Universidade Anhanguera Bandeirante, UNIBAN R. Maria Candida, 1813, Bloco G / 6o andar - 02071-013 Sao Paulo, SP (Brazil)

2013-05-06T23:59:59.000Z

331

Memantine in Moderate-to-Severe Alzheimer's Disease  

Science Journals Connector (OSTI)

...Memantine, an uncompetitive NMDA-receptor antagonist, could be of therapeutic value in Alzheimer's disease. A recent study in patients with advanced dementia (Alzheimer's disease and vascular dementia) suggested therapeutic benefits. Accordingly, we conducted a trial of the efficacy of memantine in... Overstimulation of the N-methyl-D-aspartate (NMDA) receptor by glutamate is implicated in neurodegenerative disorders. This 28-week study compared memantine, an NMDA-receptor antagonist, with placebo in persons with moderate-to-severe Alzheimer's disease. Among the patients who completed the study, memantine appeared to confer benefit in terms of activities of daily living and other measures; analysis of the last observation carried forward for the whole group supported this conclusion.

Reisberg B.; Doody R.; Stffler A.

2003-04-03T23:59:59.000Z

332

Fungus Threatens the Viability of Cotton For more than a century, the fungal disease cotton root  

E-Print Network (OSTI)

Fungus Threatens the Viability of Cotton For more than a century, the fungal disease cotton root rot has been one of the most destructive cotton diseases in Texas. Cotton root rot reduces yield. With the disease essentially eliminating harvestable cotton on affected acres, economic losses from the disease

333

CytoCom: a Cytoscape app to visualize, query and analyse disease comorbidity networks  

Science Journals Connector (OSTI)

......that can be used to search, explore, analyse...disease-disease associations in terms of bipartite graphs...uk 1 Introduction The term comorbidity refers to...disease, user needs to enter the seed disease code in the search box; CytoCom makes......

Mohammad Ali Moni; Haoming Xu; Pietro Li

2014-12-01T23:59:59.000Z

334

Journal of Alzheimer's Disease xx (20xx) xxx DOI 10.3233/JAD-132483  

E-Print Network (OSTI)

and Alzheimer's Disease as isoprostanes, neuroprostanes, acrolein, and hydrox- ynonenal (HNE), have also been

Mandal, Pravat K.

335

Seamless Correction of the Sickle Cell Disease Mutation of the HBB Gene in Human Induced  

E-Print Network (OSTI)

Seamless Correction of the Sickle Cell Disease Mutation of the HBB Gene in Human Induced ABSTRACT: Sickle cell disease (SCD) is the most common human genetic disease which is caused by a single effector nucleases; induced pluripotent stem cells; piggyBac transposon; sickle cell disease; gene therapy

Zhao, Huimin

336

Chapter 104 - Sphingolipid Disorders and the Neuronal Ceroid Lipofuscinoses or Batten Disease (Wolman Disease, Cholesteryl Ester Storage Disease, and Cerebrotendinous Xanthomatosis)  

Science Journals Connector (OSTI)

This article is a revision of the previous edition article by Rose-Mary Boustany, Talal Mousallem, volume 3, pp 24492485, 2007, Elsevier Ltd. Advances have been made in the sphingolipidoses and the many forms of Batten disease. Defects in sphingolipid synthetic enzymes and new Batten genes are identified. There is improved understanding of genetic diseases. Enzyme replacement/substrate reduction therapy are proving beneficial. Chaperones raise residual enzyme activities. Drugs affecting biochemical processes are emerging. Presymptomatic bone marrow replacement benefits certain sphingolipidoses. Viral gene therapies are encouraging in animal models Neural/non-neural stem cell therapies are under study. Efficient enzyme delivery into brain of animals/humans is being developed. These novel interventions are imperfect, and medicine is complex. Screening programs/genetic counseling/prenatal diagnosis remain the mainstays of prevention.

Rose-Mary Boustany; Ibraheem Al-Shareef; Sariah El-Haddad

2013-01-01T23:59:59.000Z

337

LLNL Chronic Beryllium Disease Protection Program Effectiveness Review, March 2011  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

LLNL-2011-03-25 LLNL-2011-03-25 Site: Lawrence Livermore National Laboratory Subject: Office of Enforcement and Oversight's Office of Safety and Emergency Management Evaluations Activity Report for the Lawrence Livermore National Laboratory Chronic Beryllium Disease Prevention Program Effectiveness Review Dates of Activity : 03/14/2011 - 03/25/2011 Report Preparer: Marvin Mielke Activity Description/Purpose: The Lawrence Livermore National Laboratory (LLNL) and the Livermore Site Office (LSO) chartered a team to conduct an effectiveness review of the issues identified with the LLNL Chronic Beryllium Disease Prevention Program (CBDPP). The team included members and observers from LLNL, LSO, the National Nuclear Security Administration (NNSA), and the

338

A Test for CreutzfeldtJakob Disease Using Nasal Brushings  

Science Journals Connector (OSTI)

...issue) concluded that real-time shaking-induced conversion (RT-QuIC) testing of olfactory mucosa samples from patients with suspected CreutzfeldtJakob disease is highly sensitive and specific, as compared with a similar test of cerebrospinal fluid samples. But Table 1 of the article shows that the... To the Editor: In their study, Orr et al. (Aug. 7 issue)1 concluded that real-time shaking-induced conversion (RT-QuIC) testing of olfactory mucosa samples from patients with suspected CreutzfeldtJakob disease is highly sensitive and specific, as ...

2014-11-06T23:59:59.000Z

339

A Test for CreutzfeldtJakob Disease Using Nasal Brushings  

Science Journals Connector (OSTI)

A Test for CreutzfeldtJakob Disease Using Nasal Brushings Original Article, N Engl J Med 2014;371:519-529. In Table 1 (page 522), in the "Time between Clinical Onset and OM Brushing" column, the values given for Patient 6 and Patient 13 should have been 9.0 and 14.0, respectively, rather than ?9... A Test for CreutzfeldtJakob Disease Using Nasal Brushings Original Article, N Engl J Med 2014;371:519-529. In Table 1 (page 522), in the Time between Clinical Onset and OM Brushing column, the values given for Patient 6 and Patient 13 should have been ...

2014-11-06T23:59:59.000Z

340

Compositions and Methods for the Treatment of Pierce's Disease  

DOE Patents (OSTI)

Chimeric anti-microbial proteins, compositions, and methods for the therapeutic and prophylactic treatment of plant diseases caused by the bacterial pathogen Xylella fastidiosa are provided. The anti-microbial proteins of the invention generally comprise a surface recognition domain polypeptide, capable of binding to a bacterial membrane component, fused to a bacterial lysis domain polypeptide, capable of affecting lysis or rupture of the bacterial membrane, typically via a fused polypeptide linker. In particular, methods and compositions for the treatment or prevention of Pierce's disease of grapevines are provided. Methods for the generation of transgenic Vitus vinefera plants expressing xylem-secreted anti-microbial chimeras are also provided.

Gupta, Goutam (Santa Fe, NM)

2008-10-07T23:59:59.000Z

Note: This page contains sample records for the topic "respiratory disease orthopedic" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


341

Discontinuing Donepezil or Starting Memantine for Alzheimer's Disease  

Science Journals Connector (OSTI)

To the Editor: In the Donepezil and Memantine in Moderate to Severe Alzheimer's Disease (DOMINO) study, Howard and coauthors (March 8 issue) found that the magnitude of benefit, as assessed with the Standardized MiniMental State Examination (SMMSE) and the Bristol Activities of Daily Living Scale... To the Editor: In the Donepezil and Memantine in Moderate to Severe Alzheimer's Disease (DOMINO) study, Howard and coauthors (March 8 issue)1 found that the magnitude of benefit, as assessed with the Standardized MiniMental State Examination (SMMSE) and ...

2012-06-07T23:59:59.000Z

342

Discontinuing Donepezil or Starting Memantine for Alzheimer's Disease  

Science Journals Connector (OSTI)

...discontinue it, or switch to memantine, an N-methyl-D-aspartatereceptor antagonist that is specifically indicated for the treatment of moderate-to-severe Alzheimer's disease in both the United Kingdom and the United States. The NHS does not approve the addition of memantine to a cholinesterase inhibitor... Donepezil, the most frequently prescribed cholinesterase inhibitor for the treatment of Alzheimer's disease, was marketed in 1997 on the basis of the results of 3-month and 6-month clinical trials showing that patients had improvements in cognitive test ...

Schneider L.S.

2012-03-08T23:59:59.000Z

343

Memantine in Moderate-to-Severe Alzheimer's Disease  

Science Journals Connector (OSTI)

To the Editor: Reisberg et al. (April 3 issue) observed that the N-methyl-D-aspartate (NMDA) antagonist memantine appears to be helpful in patients with moderate-to-severe Alzheimer's disease. There is evidence that an increased plasma homocysteine level is an independent risk factor for the development... To the Editor: Reisberg et al. (April 3 issue)1 observed that the N-methyl-D-aspartate (NMDA) antagonist memantine2 appears to be helpful in patients with moderate-to-severe Alzheimer's disease. There is evidence that an increased plasma homocysteine ...

2003-08-07T23:59:59.000Z

344

Ebola Virus Disease in the Democratic Republic of Congo  

Science Journals Connector (OSTI)

...EVD and had an epidemiologic link to a confirmed case but was not tested and did not have laboratory confirmation of the disease. A probable or suspected case was classified as confirmed when a sample from the affected person tested positive for EBOV in the laboratory. In this study, the final classification... On August 24, 2014, when the eyes of the world were on the spreading West African outbreak of Ebola virus disease (EVD), the World Health Organization (WHO) was notified of another EVD outbreak in the vicinity of Boende town, quateur province, in western ...

2014-10-15T23:59:59.000Z

345

Fruit and Nut Disease Control Products for Use in Texas  

E-Print Network (OSTI)

and/or distributors Contents 3 Fruit and Nut Disease Control PRODUCTS FOR USE IN TEXAS By George L.Philley* his listing of chemicals to control fruit diseases is a reference for county Extension agents and fruit producers in Texas... interval in days DF ?dry flowable F ?flowable L?liquid WDG ?wettable dispersable granule WG ?wettable granule WP?wettable powder days. Example: 7* indicates a 7-day interval from last application to har- vest. At the end of the publication is a listing...

Philley, George L.

2004-02-23T23:59:59.000Z

346

Ebola Virus Disease in West Africa Clinical Manifestations and Management  

Science Journals Connector (OSTI)

...testing positive for Ebola virus in blood by polymerase chain reaction (PCR). Although some patients tested positive on PCR within 24 hours after symptom onset, we found that a negative test result could not be relied on to rule out disease until 72 hours after symptoms began. Of the patients who tested... In resource-limited areas, isolation of the sick from the population at large has been the cornerstone of control of Ebola virus disease (EVD) since the virus was discovered in 1976.1 Although this strategy by itself may be effective in controlling small ...

2014-11-05T23:59:59.000Z

347

LLNL Chronic Beryllium Disease Protection Program Effectiveness Review, March 2011  

NLE Websites -- All DOE Office Websites (Extended Search)

LLNL-2011-03-25 LLNL-2011-03-25 Site: Lawrence Livermore National Laboratory Subject: Office of Enforcement and Oversight's Office of Safety and Emergency Management Evaluations Activity Report for the Lawrence Livermore National Laboratory Chronic Beryllium Disease Prevention Program Effectiveness Review Dates of Activity : 03/14/2011 - 03/25/2011 Report Preparer: Marvin Mielke Activity Description/Purpose: The Lawrence Livermore National Laboratory (LLNL) and the Livermore Site Office (LSO) chartered a team to conduct an effectiveness review of the issues identified with the LLNL Chronic Beryllium Disease Prevention Program (CBDPP). The team included members and observers from LLNL, LSO, the National Nuclear Security Administration (NNSA), and the

348

Disease pathways at the Rat Genome Database Pathway Portal: genes in contexta network approach to understanding the molecular mechanisms of disease  

Science Journals Connector (OSTI)

A new resource offering a range of pathway data and visualization, including disease pathways and related pathway suites.

Victoria Petri; G Hayman; Marek Tutaj; Jennifer R Smith; Stanley Laulederkind; Shur-Jen Wang; Rajni Nigam; Jeff De Pons; Mary Shimoyama; Melinda R Dwinell; Elizabeth A Worthey; Howard J Jacob

2014-09-30T23:59:59.000Z

349

Comparing disease expression across species: an examination of radiation and species specific disease expression in Mus musculus and Peromyscus leucopus  

NLE Websites -- All DOE Office Websites (Extended Search)

disease expression across species: an examination of radiation and species specific disease expression across species: an examination of radiation and species specific disease expression in Mus musculus and Peromyscus leucopus William Liu 1 , Benjamin Haley 1 , Mary J. Kwasny 2 , Tatjana Paunesku 1 , Gayle Woloschak 1 1. Department of Radiation Oncology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611 2. Department of Preventative Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611 From 1969 to 1992, the Janus program at Argonne National Laboratory performed a large series of radiobiology experiments, examining the effects of varying doses of neutron and gamma radiation on two disparate species of mice, Mus musculus and Peromyscus leucopus. Much of this data has since been digitized and made freely accessible online. This study aims to revisit

350

Cancer is a genetic disease1 . Although environmental  

E-Print Network (OSTI)

Cancer is a genetic disease1 . Although environmental and other non-genetic factors have roles in many stages of tumorigenesis,it is widely accepted that cancer arises because of mutations in cancer,however,does not suffice to give rise to full-blown cancer.For progression towards malignancyandinvasion

Nowak, Martin A.

351

Disease invasion: impacts on biodiversity and human health  

Science Journals Connector (OSTI)

...syndrome, bird flu and swine flu, and the revision...either a disease outbreak that dies out...within-host models a viable exercise...and analytical models of the dynamics...identify and predict future threats...the rinderpest outbreak in nineteenth...

2012-01-01T23:59:59.000Z

352

Effects of Global Climate on Infectious Disease: the Cholera Model  

Science Journals Connector (OSTI)

...impossible to predict precisely the...building predictive models for disease...events and cholera outbreaks have been increasing...Bangladesh, cholera outbreaks are related to...the nonlinear models, and interannual...variability of cholera outbreaks (124). Because...to use ENSO to predict variability in...

Erin K. Lipp; Anwar Huq; Rita R. Colwell

2002-10-01T23:59:59.000Z

353

A Global Perspective on Hantavirus Ecology, Epidemiology, and Disease  

Science Journals Connector (OSTI)

...unpredictable HPS outbreaks. In the Americas...the southwest, outbreaks of HPS cases have...been sufficient to predict the spatiotemporal...and ecological models should incorporate...threshold for disease outbreaks (23, 442a, 446...multispecies SIR-type models suggests possible...

Colleen B. Jonsson; Luiz Tadeu Moraes Figueiredo; Olli Vapalahti

2010-04-01T23:59:59.000Z

354

Factors that make an infectious disease outbreak controllable  

Science Journals Connector (OSTI)

...infectious disease outbreak dynamics that...8). This model can be used...that can help predict whether simple...stage of an outbreak. In our analyses...low variance model is appropriate...data from an outbreak of the 1978 H1N1 flu in a boys boarding...

Christophe Fraser; Steven Riley; Roy M. Anderson; Neil M. Ferguson

2004-01-01T23:59:59.000Z

355

Towards Understanding Global Spread of Disease from Everyday Interpersonal Interactions  

E-Print Network (OSTI)

spread of disease. We consider the important task of predicting the prevalence of flu- like illness into the mechanisms of dis- ease spread and significantly improve predictabil- ity of future flu outbreaks. Our media--places em- phasis on predicting which specific individuals will become afflicted with flu

Kautz, Henry

356

Tropical Environments, Human Activities, and the Transmission of Infectious Diseases  

E-Print Network (OSTI)

of water sources. The transmission of cholera, a water-borne disease, is related to sanitation practices decades as a consequence of large-scale agricultural development projects that have shifted the nature and quantity of water sources and potential mosquito breeding sites. Dracunculiasis is transmitted by a small

Gottgens, Hans

357

Infectious disease agents mediate interaction in food webs and ecosystems  

Science Journals Connector (OSTI)

...disease agents mediate interaction in food webs and ecosystems Sanja Selakovic 1 Peter...Netherlands Infectious agents are part of food webs and ecosystems via the relationship with...interactions, infectious agents influence food webs in terms of structure, functioning and...

2014-01-01T23:59:59.000Z

358

VECTOR BORNE AND ZOONOTIC DISEASES Volume 2, Number 2, 2002  

E-Print Network (OSTI)

-to-first-appearance in the eastern town- ships of Connecticut by ~29.7% (spread was from west to east). TSA revealed a similar effect the effect of local, spatially distributed environmental heterogeneities on disease spread. Using the time-to-town- ship transmission rate using Trend Surface Analysis (TSA) and then compared these estimates with those

Long, Andy

359

The Consequence of Tree Pests and Diseases for Ecosystem Services  

Science Journals Connector (OSTI)

...caterpillar as the cause of an epidemic airborne disease: Survey and analysis . Br. J. Dermatol. 149 , 990 ( 2003...across spatial scales among forest dieback, fire, and erosion in northern New Mexico...large areas of dead pine stands present a fire hazard and there...

I. L. Boyd; P. H. Freer-Smith; C. A. Gilligan; H. C. J. Godfray

2013-11-15T23:59:59.000Z

360

Fish oil can help reduce deaths from heart disease,  

E-Print Network (OSTI)

the risk of irregu- lar heart beats -- particularly in individuals with a recent heart attack. Paul CoatesFish oil can help reduce deaths from heart disease, according to new evidence reports announced evi- dence that long-chain omega- 3 fatty acids reduce heart at- tack and other problems, re- lated

Bandettini, Peter A.

Note: This page contains sample records for the topic "respiratory disease orthopedic" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


361

PEBC Breast Cancer Disease Site Group page at:  

E-Print Network (OSTI)

Evidence-based Series 8-3 was reviewed in 2011 and ARCHIVED by the Melanoma Disease Site Group (DSG) on May 20, 2011. Evidence-based Series (EBS) 8-3 ARCHIVED 2011, the resulting review report, consists of the following 5 parts:

Program In Evidence-based Care (pebc; Cancer Care Ontario (cco

2011-01-01T23:59:59.000Z

362

Intrinsically Disordered Proteins: Regulation and Disease Regulation of IDPs  

E-Print Network (OSTI)

31st Jan 2011 Intrinsically Disordered Proteins: Regulation and Disease Regulation of IDPs M. Madan ......................................................................................................................................8 #12;1 Abstract Intrinsically disordered proteins (IDPs) are often enriched in signaling and regulatory functions because the features of disordered segments permit interaction with multiple proteins

Babu, M. Madan

363

GUANYLATE CYCLASE-ACTIVATING PROTEINS AND RETINA DISEASE  

E-Print Network (OSTI)

in visual trans- duction that transcends to other neuronal Ca2+ homeostasis processes Keywords: Calcium, rod hyperpolarize. Open CNG 71 E. Carafoli and M. Brini (eds.), Calcium Signalling and Disease, 71­91. © 2007*, and PDE*). Deactivation of Figure 1. Negative cGMP/Ca2+ feedback loop. Light activates PDE which rapidly

Palczewski, Krzysztof

364

Atlas-Based Hippocampus Segmentation In Alzheimer's Disease and Mild  

E-Print Network (OSTI)

Atlas-Based Hippocampus Segmentation In Alzheimer's Disease and Mild Cognitive Impairment Owen T of Chen to align the images to the Harvard atlas, MNI atlas, and randomly-selected, manually state, registration method, choice of atlas, and man- ual tracing protocol on the agreement between

365

An approach for mining care trajectories for chronic diseases  

E-Print Network (OSTI)

An approach for mining care trajectories for chronic diseases Elias Egho1 ,Nicolas Jay1 , Chedy Ra of chronic patients. In this context, temporal data mining methods are promising tools, though lacking. We show the interest of our approach with the analysis of trajectories of care for colorectal cancer

Boyer, Edmond

366

PUBLICATION 600-080 Fish Health and Disease  

E-Print Network (OSTI)

PUBLICATION 600-080 Fish Health and Disease Striped bass (Morone saxitilis) and hybrid striped bass these fish are commonly raised in high densities under intensive aquaculture situations (e.g., cages, ponds of the viral, bacterial, fungal, and parasitic pathogens, but the fish become increasingly susceptible

Liskiewicz, Maciej

367

REVIEW ARTICLE Potato soil-borne diseases. A review  

E-Print Network (OSTI)

REVIEW ARTICLE Potato soil-borne diseases. A review Marie Fiers & Véronique Edel /Published online: 24 June 2011 # INRA and Springer Science+Business Media B.V. 2011 Abstract Potato crop potato and cause severe damages especially on tubers, the economically most impor- tant part of the plant

Paris-Sud XI, Université de

368

The smallpox story: life and death of an old disease.  

Science Journals Connector (OSTI)

...of the local smallpox surveillance team leader (total contact time during that ride...Administration of immune globulin did not change the course of the disease, and smallpox...Hardjotanojo. 1980. Residual skin changes in patients who have recovered from variola...

A M Behbehani

1983-12-01T23:59:59.000Z

369

Trypanosoma cruzi and Chagas' Disease in the United States  

Science Journals Connector (OSTI)

...S. , et al. 2008. Histopathological changes in the placentas and fetuses of mice infected...of the intergenic spacer of spliced-leader genes. Int. J. Parasitol. 40 :1599-1607...emerging diseases, 8th ed. W.B. Saunders Company, Philadelphia, PA. 177. Maguire...

Caryn Bern; Sonia Kjos; Michael J. Yabsley; Susan P. Montgomery

2011-10-01T23:59:59.000Z

370

Introduction The number of catalogued emerging infectious diseases (EIDs), and  

E-Print Network (OSTI)

to the emergence of infectious diseases include urbanization, human population growth, agricultural development of deforestation in parts of Africa are near 1% per year (FAO, 2009). Deforestation is also increasing in temperate with open spaces, have been correlated with increased anopheline mosquito densities (Yasuoka and Levins

Sehgal, Ravinder

371

Memory of myself: Autobiographical memory and identity in Alzheimer's disease  

E-Print Network (OSTI)

Memory of myself: Autobiographical memory and identity in Alzheimer's disease Donna Rose Addis autobiographical memory and identity. To test this we assessed the status of autobiographical memory and identity degree of autobiographical memory impairment was associated with changes in identity. Two tests

Addis, Donna Rose

372

IntroductionIntroduction Mercury: Monitoring Patients with ParkinsonMercury: Monitoring Patients with Parkinson''s Diseases Disease  

E-Print Network (OSTI)

IntroductionIntroduction Mercury: Monitoring Patients with ParkinsonMercury: Monitoring Patients's Disease EvaluationEvaluation Mercury ArchitectureMercury Architecture Mercury is a wireless sensor network and disconnections Node Behavior Hardware PlatformHardware Platform Usage Scenario InternetInternet http://fiji.eecs.harvard.edu/Mercury

Chen, Yiling

373

A 3-D Link between Antibiotic Resistance and Brain Disease  

NLE Websites -- All DOE Office Websites (Extended Search)

A 3-D Link between Antibiotic Resistance and Brain Disease A 3-D Link between Antibiotic Resistance and Brain Disease The story of what makes certain types of bacteria resistant to a specific antibiotic has a sub-plot that gives insight into the cause of a rare form of brain degeneration among children, according to investigators at St. Jude Children's Research Hospital. The story takes a twist as key differences among the structures of its main molecular characters disappear and reappear as they are assembled in the cell. The story is based on a study of the three-dimensional (3-D) structure of an enzyme called pantothenate kinase, which triggers the first step in the production coenzyme A (CoA), a molecule that is indispensable to all forms of life. Enzymes are proteins that speed up biochemical reactions. CoA plays a pivotal role in the cells' ability to extract energy from fatty

374

Mapping infectious disease landscapes: unmanned aerial vehicles and epidemiology  

Science Journals Connector (OSTI)

The potential applications of unmanned aerial vehicles (UAVs), or drones, have generated intense interest across many fields. \\{UAVs\\} offer the potential to collect detailed spatial information in real time at relatively low cost and are being used increasingly in conservation and ecological research. Within infectious disease epidemiology and public health research, \\{UAVs\\} can provide spatially and temporally accurate data critical to understanding the linkages between disease transmission and environmental factors. Using \\{UAVs\\} avoids many of the limitations associated with satellite data (e.g., long repeat times, cloud contamination, low spatial resolution). However, the practicalities of using \\{UAVs\\} for field research limit their use to specific applications and settings. \\{UAVs\\} fill a niche but do not replace existing remote-sensing methods.

Kimberly M. Fornace; Chris J. Drakeley; Timothy William; Fe Espino; Jonathan Cox

2014-01-01T23:59:59.000Z

375

Using Genomics to Study Human Biology and Disease  

SciTech Connect

The Human Genome Project culminated in April 2003 with the finished DNA sequence of all of the human chromosomes. This book of information, particularly in conjunction with the genome sequences of many other organisms, has already begun to revolutionize the way that biomedical scientists study our species. The identification of essentially all of our genes has provided a template upon which researchers can discover basic processes that govern cells, organs, and the whole organism, and to understand the fundamental causes of the diseases that occur when something goes wrong with a gene or a set of genes. The Genome Project has already made it possible to identify the genes that are defective in more than 1,000 rare inherited diseases, and these discoveries have helped to understand the mechanisms of the more common forms of these disorders. This understanding of primary defects in diseases - which is translated as mutations in genes that encode proteins that serve specific functions - is transforming the way that biotechnology and pharmaceutical companies identify drug targets, and a few notable cases have already had a striking impact on specific diseases. In addition, it has become clear that the differential response to drugs in human populations is heavily influenced by genes, and a whole field called pharmacogenetics has begun to identify these genetic factors. Such knowledge will allow physicians to prescribe drugs targeted to each individual, with the potential to increase efficacy and decrease side-effects. Determining the DNA sequence of the human genome and identifying the genes has been an exciting endeavor, but we are only just beginning to understand the treasures present in all of our DNA. My presentation will briefly describe the road we took to get the sequence, as well as the tools that we are developing to unlock its secrets.

Myers, Ricard M. (Stanford University School of Medicine) [Stanford University School of Medicine

2005-04-06T23:59:59.000Z

376

A nonsense mutation in PRNP associated with clinical Alzheimer's disease  

Science Journals Connector (OSTI)

Abstract Here, we describe a nonsense haplotype in PRNP associated with clinical Alzheimer's disease. The patient presented an early-onset of cognitive decline with memory loss as the primary cognitive problem. Whole-exome sequencing revealed a nonsense mutation in PRNP (NM_000311, c.C478T; p.Q160*; rs80356711) associated with homozygosity for the V allele at position 129 of the protein, further highlighting how very similar genotypes in PRNP result in strikingly different phenotypes.

Rita Guerreiro; Jos Brs; Aleksandra Wojtas; Rosa Rademakers; John Hardy; Neill Graff-Radford

2014-01-01T23:59:59.000Z

377

Spatial simulations of infectious disease: environment, behaviour, and their interaction in a primate population.  

E-Print Network (OSTI)

??Recent trends in emerging and re-emerging human infectious disease indicate that zoonotic diseases are on the rise (e.g., SARS, Swine Flu, Bird flu, Ebola, and (more)

Bonnell, Tyler

2014-01-01T23:59:59.000Z

378

E-Print Network 3.0 - autoimmune demyelinating disease Sample...  

NLE Websites -- All DOE Office Websites (Extended Search)

NeuroVirology Summary: virus-induced demyelinating disease Jami L Bennett,1 Adam Elhofy,1 Mauro C Dal Canto,1 Mari Tani,2... , immune-mediated demyelinating disease (Miller et al,...

379

Diagnostic prediction of complex diseases using phase-only correlation based on virtual sample template  

E-Print Network (OSTI)

Motivation: Complex diseases induce perturbations to interaction and regulation networks in living systems, resulting in dynamic equilibrium states that differ for different diseases and also normal states. Thus identifying ...

Wang, Shu-Lin; Fang, Yaping; Fang, Jianwen

2013-05-09T23:59:59.000Z

380

E-Print Network 3.0 - acute vogt-koyanagi-harada disease Sample...  

NLE Websites -- All DOE Office Websites (Extended Search)

vogt-koyanagi-harada disease Search Powered by Explorit Topic List Advanced Search Sample search results for: acute vogt-koyanagi-harada disease Page: << < 1 2 3 4 5 > >> 1 sistent...

Note: This page contains sample records for the topic "respiratory disease orthopedic" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


381

E-Print Network 3.0 - arthritis disease activity Sample Search...  

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Sample search results for: arthritis disease activity Page: << < 1 2 3 4 5 > >> 1 CURRICULUM VITAE DANIEL J. McCARTY, M.D. Summary: of Arthritis and Metabolic Diseases, Department...

382

E-Print Network 3.0 - alzheimers disease ad Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

Sample search results for: alzheimers disease ad Page: << < 1 2 3 4 5 > >> 1 4.2.5 NANOTECHNOLOGY TOWARDS CLINICAL DIAGNOSIS OF ALZHEIMER'S DISEASE D. Georganopoulu, L. Chang,...

383

Fluid and structural modeling of the disease-free and atherosclerotic human carotid bifurcation  

E-Print Network (OSTI)

Cardiovascular disease is the leading cause of death in the United States. It claims more lives each year than the next 7 leading causes of death combined. Atherosclerosis is a major cause of cardiovascular disease and is ...

Younis, Hesham F. (Hesham Farouk)

2002-01-01T23:59:59.000Z

384

E-Print Network 3.0 - apparently disease-free areas Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

disease-free areas Search Powered by Explorit Topic List Advanced Search Sample search results for: apparently disease-free areas Page: << < 1 2 3 4 5 > >> 1 Declaration from the...

385

Design of a numerical model for simulation of blood microcirculation and study of sickle cell disease  

E-Print Network (OSTI)

Sickle cell disease is nowadays one of the most challenging blood diseases, where patients suffer from both chronic and acute episodes of painful medical conditions. In particular, unpredictable crises due to blood vessel ...

Le Floch-Yin, Franois T. (Franois Thomas)

2010-01-01T23:59:59.000Z

386

E-Print Network 3.0 - amyloid heart disease Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

heart disease Search Powered by Explorit Topic List Advanced Search Sample search results for: amyloid heart disease Page: << < 1 2 3 4 5 > >> 1 Imaging and In Vivo Quantitation of...

387

E-Print Network 3.0 - arrhythmia-related heart disease Sample...  

NLE Websites -- All DOE Office Websites (Extended Search)

arrhythmia-related heart disease Search Powered by Explorit Topic List Advanced Search Sample search results for: arrhythmia-related heart disease Page: << < 1 2 3 4 5 > >> 1...

388

High-Oleic Ground Beef and Risk Factors for Cardiovascular Disease in Men and Postmenopausal Women  

E-Print Network (OSTI)

About half of all deaths in developed countries are caused by cardiovascular disease. It is well known that cardiovascular disease (CVD) risk can be influenced by diet, but optimal dietary content of fatty acids continues to be debated. The effect...

Ghahramany, Ghazal

2012-07-16T23:59:59.000Z

389

Innovative Alzheimer's disease clinical trial design in the coming age of biomarkers  

E-Print Network (OSTI)

Alzheimer's disease (AD) is a field with huge unmet need and only a few symptomatic treatments with limited efficacy have been made available to patients. With the testing of disease-modifying drugs in recent years, the ...

Hillerstrom, Hampus

2008-01-01T23:59:59.000Z

390

E-Print Network 3.0 - allergic ocular diseases Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

), asthma, chronic bronchitis, emphysema, epilepsy, gastricpeptic ulcer dis- ease, gout, ocular... and systemic hypertension, peripheral vascular disease, and stroke (ischemic...

391

E-Print Network 3.0 - acid peptic disease Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

), asthma, chronic bronchitis, emphysema, epilepsy, gastricpeptic ulcer dis- ease, gout, ocular... and systemic hypertension, peripheral vascular disease, and stroke (ischemic...

392

E-Print Network 3.0 - alcohol-induced liver disease Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

-specific chaperone, in normal and diseased human liver. Lab ... Source: Groningen, Rijksuniversiteit - Centre for Ecological and Evolutionary Studies, Department of...

393

E-Print Network 3.0 - aortic valve disease Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

disease, fibrotic... aortic ... Source: Simmons, Craig A. - Department of Mechanical and Industrial Engineering, University of Toronto Collection: Engineering ; Biology and...

394

English walnut rootstocks help avoid blackline disease, but produce less than Paradox hybrid  

E-Print Network (OSTI)

rootstock selection can help to prevent blackline infection.English walnut rootstocks help avoid blackline disease, but

Grant, Joseph A.; McGranahan, Gale H.

2005-01-01T23:59:59.000Z

395

E-Print Network 3.0 - artery disease challenges Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

fatal disease. Continued... , Olivier Sitbon, Ari Chaouat, Michle Bertocchi, Gilbert Habib, Pulmonary ... Source: Engman, David M. - Departments of Pathology &...

396

E-Print Network 3.0 - artery disease share Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

fatal disease. Continued... , Olivier Sitbon, Ari Chaouat, Michle Bertocchi, Gilbert Habib, Pulmonary ... Source: Engman, David M. - Departments of Pathology &...

397

Inferring disease association using clinical factors in a combinatorial manner and their use in drug repositioning  

Science Journals Connector (OSTI)

......some unexpected correlations such as the gout and heart disease correlation as well as...repositioning. As a result, we found that the gout and heart diseases pairs were positioned...we investigated relationships between gout and heart diseases from literature, and......

Jinmyung Jung; Doheon Lee

2013-08-15T23:59:59.000Z

398

Eur Heart J. Author manuscript History of coronary heart disease and cognitive performance in midlife: the  

E-Print Network (OSTI)

Eur Heart J. Author manuscript Page /1 9 History of coronary heart disease and cognitive: Archana Singh-Manoux Abstract Aims Some studies show coronary heart for this association. Coronary heart disease is a global problem, with the risk of disease shown to increase as12

Paris-Sud XI, Université de

399

Machine Learning Algorithms for Predicting Severe Crises of Sickle Cell Disease  

E-Print Network (OSTI)

Machine Learning Algorithms for Predicting Severe Crises of Sickle Cell Disease Clara Allayous of an acute splenic sequestration crisis (ASSC), a serious symptom of sickle cell disease (SCD). Precisely, in contrast to the logistic regression approach. Keywords and phrases: sickle cell disease, ranking, ROC curve

Emilion, Richard

400

Cost-Sensitive Risk Stratification in the Diagnosis of Heart Disease  

E-Print Network (OSTI)

Cost-Sensitive Risk Stratification in the Diagnosis of Heart Disease Selen Uguroglu and Jaime Pittsburgh, PA 15212 Abstract We investigate machine learning methods for diagnos- tic screening of heart disease. Coronary heart disease is the leading cause of death in the US, causing more deaths than all

Carbonell, Jaime

Note: This page contains sample records for the topic "respiratory disease orthopedic" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
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to obtain the most current and comprehensive results.


401

THe heartTruTH Heart disease is the #1 killer of  

E-Print Network (OSTI)

THe heartTruTH® #12;Heart disease is the #1 killer of women, but many women do not know they are at risk. The Heart Truth® campaign aims to give women a personal and urgent wake-up call about their risk of heart disease. The red Dress® is the national symbol for women and heart disease awareness introduced

Baker, Chris I.

402

Heart . Author manuscript Effects of depressive symptoms and coronary heart disease and their  

E-Print Network (OSTI)

Heart . Author manuscript Page /1 11 Effects of depressive symptoms and coronary heart disease separately in patients with coronary heart disease (CHD) and in populations healthy at study inception and CHD status. OBJECTIVE To examine effects of depressive symptoms and coronary heart disease

Paris-Sud XI, Université de

403

Integrating natural and social science perspectives on plant disease risk, management and policy formulation  

Science Journals Connector (OSTI)

...and disease: newly emerging diseases. In Encyclopedia of microbiology (ed. Moselio, S.), pp. 647-654, 3rd edn. Dordrecht...doi:10.1146/annurev.py.11.090173.000303 ) 10 Gilbert, G. S. 2002 Evolutionary ecology of plant diseases in natural...

2011-01-01T23:59:59.000Z

404

Glycosyl-phosphatidylinositol (GPI)-anchored membrane association of the porcine reproductive and respiratory syndrome virus GP4 glycoprotein and its co-localization with CD163 in lipid rafts  

SciTech Connect

The porcine reproductive and respiratory syndrome virus (PRRSV) glycoprotein 4 (GP4) resembles a typical type I membrane protein in its structure but lacks a hydrophilic tail at the C-terminus, suggesting that GP4 may be a lipid-anchored membrane protein. Using the human decay-accelerating factor (DAF; CD55), a known glycosyl-phosphatidylinositol (GPI) lipid-anchored protein, chimeric constructs were made to substitute the GPI-anchor domain of DAF with the putative lipid-anchor domain of GP4, and their membrane association and lipase cleavage were determined in cells. The DAF-GP4 fusion protein was transported to the plasma membrane and was cleaved by phosphatidylinositol-specific phospholipase C (PI-PLC), indicating that the C-terminal domain of GP4 functions as a GPI anchor. Mutational studies for residues adjacent to the GPI modification site and characterization of respective mutant viruses generated from infectious cDNA clones show that the ability of GP4 for membrane association corresponded to virus viability and growth characteristics. The residues T158 ({omega} - 2, where {omega} is the GPI moiety at E160), P159 ({omega} - 1), and M162 ({omega} + 2) of GP4 were determined to be important for virus replication, with M162 being of particular importance for virus infectivity. The complete removal of the peptide-anchor domain in GP4 resulted in a complete loss of virus infectivity. The depletion of cholesterol from the plasma membrane of cells reduced the virus production, suggesting a role of lipid rafts in PRRSV infection. Remarkably, GP4 was found to co-localize with CD163 in the lipid rafts on the plasma membrane. Since CD163 has been reported as a cellular receptor for PRRSV and GP4 has been shown to interact with this receptor, our data implicates an important role of lipid rafts during entry of the virus.

Du, Yijun [Department of Pathobiology, University of Illinois at Urbana-Champaign, 2001 South Lincoln Ave, Urbana, IL 61802 (United States) [Department of Pathobiology, University of Illinois at Urbana-Champaign, 2001 South Lincoln Ave, Urbana, IL 61802 (United States); Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan (China); Pattnaik, Asit K. [School of Veterinary Medicine and Biomedical Sciences and the Nebraska Center for Virology, University of Nebraska-Lincoln, Lincoln, NE 68583-0900 (United States)] [School of Veterinary Medicine and Biomedical Sciences and the Nebraska Center for Virology, University of Nebraska-Lincoln, Lincoln, NE 68583-0900 (United States); Song, Cheng [Department of Pathobiology, University of Illinois at Urbana-Champaign, 2001 South Lincoln Ave, Urbana, IL 61802 (United States)] [Department of Pathobiology, University of Illinois at Urbana-Champaign, 2001 South Lincoln Ave, Urbana, IL 61802 (United States); Yoo, Dongwan, E-mail: dyoo@illinois.edu [Department of Pathobiology, University of Illinois at Urbana-Champaign, 2001 South Lincoln Ave, Urbana, IL 61802 (United States)] [Department of Pathobiology, University of Illinois at Urbana-Champaign, 2001 South Lincoln Ave, Urbana, IL 61802 (United States); Li, Gang, E-mail: dyoo@illinois.edu [Department of Pathobiology, University of Illinois at Urbana-Champaign, 2001 South Lincoln Ave, Urbana, IL 61802 (United States) [Department of Pathobiology, University of Illinois at Urbana-Champaign, 2001 South Lincoln Ave, Urbana, IL 61802 (United States); Institute of Animal Science and Veterinary Medicine, Chinese Academy of Agricultural Sciences, Beijing (China)

2012-03-01T23:59:59.000Z

405

The Diet-Heart Hypothesis: a critical appraisal of the relationship between diet and coronary artery disease  

E-Print Network (OSTI)

for Prevention of Coronary Heart Disease. JAMA. 2002;288:M. Fish consumption and coronary heart disease mortality: aacid and risk of ischemic heart disease among women. Am J

Jurewitz, Daniel L

2007-01-01T23:59:59.000Z

406

New England Foot and Mouth Disease Tabletop Exercise  

SciTech Connect

The Multiscale Epidemiologic/Economic Simulation and Analysis (MESA) Decision Support System (DSS) is the product of investments that began in FY05 by the Department of Homeland Security (DHS) Science and Technology Directorate and continue today with joint funding by both DHS and the US Department of Agriculture (USDA). The DSS consists of a coupled epidemiologic/economic model, a standalone graphical user interface (GUI) that supports both model setup and post-analysis, and a Scenario Bank archive to store all content related to foreign animal disease (FAD) studies (Figure 1). The MESA epi model is an object-oriented, agent-based, stochastic, spatio-temporal simulator that parametrically models FAD outbreaks and response strategies from initial disease introduction to conclusion over local, regional, and national scales. Through its output database, the epi model couples to an economic model that calculates farm-level impacts from animal infections, responsive control strategies and loss of trade. The MESA architecture contains a variety of internal models that implement the major components of the epi simulation, including disease introduction, intra-herd spread, inter-herd spread (direct and indirect), detection, and various control strategies (movement restrictions, culling, vaccination) in a highly configurable and extensible fashion. MESA will produce both overall and daily summary statistics for the outbreak, epidemic curves, and costs associated with the outbreak. This information can be used to reconstruct and analyze the course of the outbreak. Geographical information produced by MESA can be used to produce maps and movies as visual aids to understand the distribution characteristics of a simulated outbreak.

Hullinger, P

2008-09-30T23:59:59.000Z

407

The First Case of Ebola Virus Disease Acquired outside Africa  

Science Journals Connector (OSTI)

...assistant has subsequently recovered and was discharged from the hospital on November 5. Signs of infection have not developed in any of the eight health care workers who were in contact with this nurse assistant, and all have passed the 21-day incubation period after exposure. No other secondary cases... To the Editor: The current epidemic of Ebola virus disease (EVD) remains essentially confined to West Africa.1 We present a case of transmission of the virus associated with the care of a patient who was transported from Sierra Leone to Spain on ...

2014-11-19T23:59:59.000Z

408

Chapter 5 Lyme Disease SpirocheteTickHost Interactions  

Science Journals Connector (OSTI)

Ticks and hosts engage in a subtle interplay during the period ticks take blood from vertebrate hosts. While the host mounts an inflammatory and immune response to the tick bite, ticks modulate this response through anti-haemostatic, anti-inflammatory and immunosuppressive components in their saliva. In the midst of this process, a tick-borne bacterial agent, the Lyme disease spirochete (Borrelia burgdorferi), takes advantage of tick-derived proteins to maximize its chances of surviving transmission from the tick to the vertebrate host and then back to the tick again. The tickspirochetehost interrelationship is the subject of this chapter.

Katharine R. Tyson; Joseph Piesman

2009-01-01T23:59:59.000Z

409

Brief Report: Emergence of Zaire Ebola Virus Disease in Guinea  

Science Journals Connector (OSTI)

...gene to test samples obtained from 20 hospitalized patients who were suspected of being infected with a hemorrhagic fever virus. In addition, we performed EBOV-specific real-time RT-PCR assays targeting the glycoprotein (GP) or nucleoprotein (NP) gene. Samples from 15 of 20 patients tested positive... In March 2014, an outbreak of Ebola virus disease associated with a high fatality rate was identified in Guinea, with evidence of ongoing person-to-person transmission. In this update to the preliminary report, the virus is found to be a new strain related to Zaire ebolavirus.

Baize S.; Pannetier D.; Oestereich L.

2014-10-09T23:59:59.000Z

410

Disease and Suspicion after the Persian Gulf War  

Science Journals Connector (OSTI)

In 1990 the United States and its allies sent close to a million troops to the Persian Gulf. Fewer than 150 Americans died during the six-week war against Iraq, but many veterans now fear that the Persian Gulf War ruined their health. Six years later, there is wide publicity about excess disease and... In 1990 the United States and its allies sent close to a million troops to the Persian Gulf. Fewer than 150 Americans died during the six-week war against Iraq,1 but many veterans now fear that the Persian Gulf War ruined their health. Six years later, ...

Campion E.W.

1996-11-14T23:59:59.000Z

411

Blood Pressure in Early Autosomal Dominant Polycystic Kidney Disease  

Science Journals Connector (OSTI)

...mixed model with separate slopes for the short-term phase (baseline to 4 months) and the long-term phase (>4 months) to compare treatment groups. We tested slopes for overall changes and for changes in the short-term and long-term phases. Remaining secondary outcomes were analyzed with the use of generalized... In patients with autosomal dominant polycystic kidney disease, the rate of increase in total kidney volume was not slowed by lisinopril and telmisartan, as compared with lisinopril and placebo, but was slowed with rigorous blood-pressure control.

Schrier R.W.; Abebe K.Z.; Perrone R.D.

2014-12-11T23:59:59.000Z

412

Angiotensin Blockade in Late Autosomal Dominant Polycystic Kidney Disease  

Science Journals Connector (OSTI)

...compared with the use of logistic regression. We tested for a priori hypothesized differential treatment effects on the time to disease progression according to age at screening, sex, baseline estimated GFR, and baseline urinary albumin excretion, using tests for interactions. Interim analyses for the primary... This trial tested single versus dual inhibition of the reninangiotensinaldosterone system in ADPKD. ACE-inhibitor monotherapy controlled blood pressure in most patients. Adding an angiotensin IIreceptor blocker did not alter the decline in estimated GFR.

Torres V.E.; Abebe K.Z.; Chapman A.B.

2014-12-11T23:59:59.000Z

413

Storage and Diseases of the Sweet Potato in Texas.  

E-Print Network (OSTI)

readily apparent upon casual examination of the lot, and that any damage from the caum mentionecl can be removed by the ordinary process of paring witnout appreciable increase in waste over that which would oc-cur if the sweet potatoes were perfect. d...TEXAS A~~RICUL~~R~L EXPERIMENT STATION AGRICULTURAL AND MECHANICAL COLLEGE OF TEXAS W. B. BIZZELL, President BULLETIN TuO. 250 OCTOBER, 1919 EXPERIMENT STATION AND EXTENSION SERVICE COOPERATING STORAGE AND DISEASES OF THE SWEET POTATO...

Youngblood, B. (Bonney)

1919-01-01T23:59:59.000Z

414

Effect of Cigar Smoking on the Risk of Cardiovascular Disease, Chronic Obstructive Pulmonary Disease, and Cancer in Men  

Science Journals Connector (OSTI)

...arterial disease, COPD and related conditions, and cancer at selected sites in a large cohort of men who were members of a health maintenance organization. Methods. Study Cohort. The study cohort was composed of 17,774 men 30 to 85 years of age who were enrolled in the Kaiser Permanente Medical Care... Cigar sales in the United States increased nearly 50 percent between 1993 and 1997. Over the same period, sales of large, premium cigars increased by 68 percent,1 reversing a 20-year decline in cigar consumption that began in the early 1970s. The upward ...

Iribarren C.Tekawa I.S.Sidney S.Friedman G.D.

1999-06-10T23:59:59.000Z

415

Respiratory distress with acitretin, reversal by corticosteroid  

E-Print Network (OSTI)

developed high fever, dry cough and dyspnea while undergoingfor high fever (39.5C), dry cough and dyspnoea. He had beentherapy, fever and dry cough were not improving and his

Cuhadaroglu, Caglar; Korular, Didem; Erelel, Mustafa; Kiyan, Esen; Kiliaslan, Zeki

2001-01-01T23:59:59.000Z

416

Winter Infections: Influenza, Respiratory Syncytial Virus (RSV)  

E-Print Network (OSTI)

spread? Sick person can spread influenza by: ­ Touching ­ Sneezing ­ Coughing Picture: newbedfordguide Fever Cough Fatigue (feel "worn out") Headaches Body aches Runny nose #12;Influenza ("Flu") Treatments paralysis) #12;"MythBusters" Reported That: Sneezes can travel ~35 mph Cough/sneeze droplets can travel

Goldman, Steven A.

417

Ghosting of Pulmonary Nodules with Respiratory Motion  

E-Print Network (OSTI)

Usingan InVitro Pediatric Model Gary D. ~ u k e r ' Kyongtae T. Bae Marilyn J. Siegel Steven Don James A: Mallinckrodt lnst~tuteof Radiology, Wash- ington University School of Medicine, 510 S. Kingshigh- way Blvd., St

Virginia Tech

418

Modifying Proteins to Combat Disease | Advanced Photon Source  

NLE Websites -- All DOE Office Websites (Extended Search)

Higher Temperature at the Earth's Core Higher Temperature at the Earth's Core Clues about Rheumatoid Arthritis Damage Science Highlights Archives: 2013 | 2012 | 2011 | 2010 2009 | 2008 | 2007 | 2006 2005 | 2004 | 2003 | 2002 2001 | 2000 | 1998 | Subscribe to APS Science Highlights rss feed Modifying Proteins to Combat Disease JANUARY 22, 2013 Bookmark and Share Structure of the human PRMT5:MEP50 hetero-octameric complex bound to a substrate peptide and a cofactor analog. Cartoon representations of the PRMT5 monomers are colored blue, green, wheat, and yellow, while the MEP50 molecules are in red. Highlighted in stick representation are the substrate peptide derived from histone H3 in magenta, and the cofactor analog in orange. Transmitting from one generation to the next the genetic message encoded in

419

Hippocampal novelty activations in schizophrenia: Disease and medication effects  

Science Journals Connector (OSTI)

We examined hippocampal activation in schizophrenia (SZ) with fMRI BOLD in response to the presentation of novel and familiar scenes. Voxel-wise analysis showed no group differences. However, anatomical region-of-interest analyses contrasting normal (NL), SZ-on-medication (SZ-ON), SZ-off-medication (SZ-OFF) showed substantial differences in MTL-based novelty responding, accounted for by the reduction in novelty responses in the SZ-OFF predominantly in the anterior hippocampus and parahippocampal cortex. These differences in novelty-based activation in the SZ-OFF group represent disease characteristics of schizophrenia without confounding effects of antipsychotic medication and illustrate the tendency of antipsychotic drug treatment to improve memory functions in schizophrenia.

Carol A. Tamminga; Binu P. Thomas; Ronald Chin; Perry Mihalakos; Kenneth Youens; Anthony D. Wagner; Alison R. Preston

2012-01-01T23:59:59.000Z

420

When you hear the term "heart disease," what's your first reaction? Like many women, you may think, "That's a  

E-Print Network (OSTI)

When you hear the term "heart disease," what's your first reaction? Like many women, you may think, "That's a man's disease." But here's The Heart Truth: Heart disease is the #1 killer of Latinas in the United States. Together with stroke, heart disease accounts for a third of all deaths among Latinas

Bandettini, Peter A.

Note: This page contains sample records for the topic "respiratory disease orthopedic" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
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We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


421

A Quest Halting the Progression of Autosomal Dominant Polycystic Kidney Disease  

Science Journals Connector (OSTI)

...autosomal dominant polycystic kidney disease (ADPKD) ultimately occurs in most patients, even with the best available therapy. Clinical trials that test strategies to prevent or at least forestall progression are emblematic of the current era, yet none, to date, have greatly affected outcome. Because... Progression to end-stage kidney disease in autosomal dominant polycystic kidney disease (ADPKD) ultimately occurs in most patients, even with the best available therapy. Clinical trials that test strategies to prevent or at least forestall progression are ...

2014-11-15T23:59:59.000Z

422

E-Print Network 3.0 - alzheimers disease caregivers Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

group for family caregivers and health... professionals The Alzheimer List is a free public service of the Alzheimer's Disease Research Center (ADRC... -mail based support...

423

E-Print Network 3.0 - active disease caused Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

Princeton University Press. of foliar diseases caused by polycyclic, specialized, wind... K. A. Garrett and C. M. Cox. Applied biodiversity science: Managing emerging...

424

Associations between laryngeal and cough dysfunction in motor neuron disease with bulbar involvement.  

E-Print Network (OSTI)

??PURPOSE: Cough, a fundamental mechanism in airway protection, depends on true vocal fold (TVF) function and airflow. In individuals with motor neuron disease (MND), cough (more)

Britton, Deanna J.

2013-01-01T23:59:59.000Z

425

E-Print Network 3.0 - anus diseases Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

University of Arizona Collection: Biology and Medicine ; Engineering 32 Local Scale Effects of Disease on Biodiversity Katherine F. Smith,1,2 Summary: Local Scale Effects...

426

Hailey-Hailey disease exacerbated by multiple pregnancies: case report and review of the literature  

E-Print Network (OSTI)

2. [PMID: 16957441] 5. Hohl D, Mauro T. Darier Disease andT, Ogawa H, Ikeda S, Mauro T, Epstein EH Jr. Mutations in

Mauzo, Shakuntala H; Sulit, Daryl J

2014-01-01T23:59:59.000Z

427

E-Print Network 3.0 - agonist alleviates disease Sample Search...  

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this disease... . - Adrenoceptor agonists have been used to treat asthma for more than a century. The mechanisms of action of 2... -adrenoceptor agonists are well characterized...

428

E-Print Network 3.0 - acute gastrointestinal disease Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

erythematosus (SLE) 3. Scleroderma (Systemic sclerosis) 4. Crystal induced disease (Gout... : acute and chronic 3. Connective tissue 4. Joints (focus on synovium) 5....

429

E-Print Network 3.0 - acute bacterial diseases Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

erythematosus (SLE) 3. Scleroderma (Systemic sclerosis) 4. Crystal induced disease (Gout... : acute and chronic 3. Connective tissue 4. Joints (focus on synovium) 5....

430

The Ethics of Early Evidence Preparing for a Possible Breakthrough in Alzheimer's Disease  

Science Journals Connector (OSTI)

Being on the cusp of a potential medical breakthrough for a serious disease can pose substantial ethical challenges. One current example arises from a recent study demonstrating in a single mouse model in one laboratory that the drug bexarotene is effective in treating Alzheimer's disease (see... A recent study demonstrated, in a mouse model in one lab, that bexarotene (FDA-approved for use in non-Hodgkin's lymphoma) is effective against Alzheimer's disease. What should physicians do if patients with Alzheimer's disease begin seeking off-label prescriptions?

Lowenthal J.Hull S.C.Pearson S.D.

2012-08-09T23:59:59.000Z

431

Pediatric Intestinal Failure Associated Liver Disease is Revered with Six Months of Intravenous Fish Oil.  

E-Print Network (OSTI)

??Pediatric intestinal failure associated liver disease (IFALD) is associated with a high morbidity and mortality. Studies have suggested that when intravenous (IV) soybean oil (SO) (more)

Calkins, Kara

2013-01-01T23:59:59.000Z

432

E-Print Network 3.0 - ameliorate coral disease Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

Search Sample search results for: ameliorate coral disease Page: << < 1 2 3 4 5 > >> 1 Climate change impedes scleractinian corals as primary reef ecosystem engineers Summary:...

433

Holdover inoculum of Pseudomonas syringae pv. alisalensis from broccoli raab causes disease in subsequent plantings  

E-Print Network (OSTI)

about P. syringae pv. Plant Disease / August 2006 ABSTRACTsyringae pv. lachrymans in soil, plant debris, and thesyringae pv. tomato populations on field tomato plants.

Cintas, N A; Koike, S T; Bunch, R A; Bull, C T

2006-01-01T23:59:59.000Z

434

Isolation of the Left Innominate Artery in an Elderly Patient Without Congenital Heart Disease  

SciTech Connect

We report a rare anomaly consisting of a right aortic arch with an isolated left innominate artery in an elderly man without congenital heart disease.

Boren, Edwin L. Jr.; Matchett, W. Jean [Department of Radiology, Slot 556, University of Arkansas for Medical Sciences, 4301 West Markham Street, Little Rock, AR 72210 (United States); Gagne, Paul J. [Department of Surgery, University of Arkansas for Medical Sciences, 4301 West Markham Street, Little Rock, AR 72210 (United States); McFarland, David R. [Department of Radiology, Slot 556, University of Arkansas for Medical Sciences, 4301 West Markham Street, Little Rock, AR 72210 (United States)

2000-01-15T23:59:59.000Z

435

Protein folding stress in neurodegenerative diseases: a glimpse into the ER .  

E-Print Network (OSTI)

??Several neurodegenerative diseases share common neuropathology, primarily featuring the presence in the brain of abnormal protein inclusions containing specific misfolded proteins. Recent evidence indicates that (more)

Matus, Soledad

2011-01-01T23:59:59.000Z

436

E-Print Network 3.0 - artery disease caused Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

? Peripheral Arterial Disease (PAD) is a serious condition that is associated with heart attack and stroke. PAD... results in a narrowing of the arteries that carry blood to...

437

E-Print Network 3.0 - autosomal dominant diseases Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

Alexander disease patients ... Source: Kalil, Ronald E. - Neuroscience Training Program & W.M. Keck Laboratory for Biological Imaging, University of Wisconsin at Madison...

438

E-Print Network 3.0 - alzheimer disease patterns Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

Carnegie Mellon University Collection: Biology and Medicine 25 Modeling Intrinsically Disordered Proteins A number of neurodegenerative disorders such as Alzheimer's disease...

439

Randomized Feeding Intervention in Infants at High Risk for Celiac Disease  

Science Journals Connector (OSTI)

...age at the diagnosis of celiac disease or at the last assessment or withdrawal from the study (when data were censored). For comparison, a log-rank test (two-sided) was used, stratified according to participating country. The hazard ratio for celiac disease in the gluten group, as compared with the placebo... In this trial involving infants at high risk for celiac disease, the introduction of gluten at 4 months of age, as compared with delayed exposure to gluten until 6 months of age, did not reduce the risk of celiac disease at 3 years of age.

Vriezinga S.L.; Auricchio R.; Bravi E.

2014-10-02T23:59:59.000Z

440

E-Print Network 3.0 - artery disease potential Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

peripheral arterial disease, enhancement of stem cell therapies... -assembly code that led to these artificial extracellular matrices and their potential use in regenerative......

Note: This page contains sample records for the topic "respiratory disease orthopedic" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


441

A WEARABLE SENSOR SUITE AND MOBILE APPLICATION FOR PARKINSON'S DISEASE TREMOR ANALYSIS IN RURAL AREAS.  

E-Print Network (OSTI)

?? Parkinson's Disease (PD) is a neurodegenerative disorder that affects approximately 7 to 10 million people worldwide. Patients who suffer from PD usually attend regular (more)

Peltier, Kara L.

2014-01-01T23:59:59.000Z

442

A Prioritized Research Agenda for Prevention and Control of Noncommunicable Diseases  

E-Print Network (OSTI)

haemoglobin disorders (sickle cell disease and thalassae-quality of care for sickle cell anaemia and thalassaemia * *carriers, such as sickle cell anaemia or thalassaemia); (ii)

WHO

2011-01-01T23:59:59.000Z

443

E-Print Network 3.0 - acute gallbladder disease Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

Computer Technologies and Information Sciences ; Biology and Medicine 34 AND THERAPY OF SICKLE CELL DISEASE Summary: experiencing acute or severe exac- erbations of sickle cell...

444

E-Print Network 3.0 - atherosclerotic vascular disease Sample...  

NLE Websites -- All DOE Office Websites (Extended Search)

provide objective quantitative data characterising Summary: . References: 1. Fact report: Heart, stroke and vascular diseases: AIHW Cat. No. CVD 27. Canberra: AIHW......

445

E-Print Network 3.0 - artery disease drugs Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

Drug Plan Benefit Guide Revised 101510 Summary: artery disease or congestive heart failure) are eligible for the Value-Based Prescription Drug Plan... (Coronary Artery...

446

Predictors of occupational skin disease among seafood processing workers in the Western Cape.  

E-Print Network (OSTI)

??Includes abstract. Occupational skin disease is common in seafood processing workers. While previous studies have reported an increased prevalence of symptoms (as high as 50%) (more)

Burdzik, Amy.

2012-01-01T23:59:59.000Z

447

E-Print Network 3.0 - allergic eye diseases Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

Measles, mumps, and rubella are serious diseases. Measles Measles virus causes rash, cough, runny nose... , eye irritation, and fever. It can lead to ear infection,...

448

E-Print Network 3.0 - aggravated creutzfeldt-jacob disease Sample...  

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Proteins are the workhorses of the body, and the enigmatic process... secrets of protein folding that could lead to improved diagnosis and treatment of diseases Source: Daggett,...

449

A fuzzy logic controller for intestinal levodopa infusion in Parkinsons disease.  

E-Print Network (OSTI)

?? The aim of this work is to evaluate the fuzzy system for different types of patients for levodopa infusion in Parkinson Disease based on (more)

Jiang, Xiaowen

2010-01-01T23:59:59.000Z

450

E-Print Network 3.0 - affected vector-borne diseases Sample Search...  

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disease systems... between species diversity and ... Source: Cary Institute of Ecosystem Studies, Millbrook, New York; Holt, Robert D. - Department of Biology, University of...

451

E-Print Network 3.0 - activity disease duration Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

Collection: Biology and Medicine 11 ALL YOU EVER WANTED TO KNOW ABOUT FUSARIUM PATCH MICRODOCHIUM PAT Summary: disease of cool, wet maritime climates is caused by a...

452

Right Ventricular Assessment by Real-time Three-dimensional Echocardiography in Congenital Heart Disease.  

E-Print Network (OSTI)

??abstractThe remarkable improvement in survival of patients with congenital heart disease has led to a growing number of adult patients. In particular, patients with more (more)

H.B. van der Zwaan (Heleen)

2011-01-01T23:59:59.000Z

453

E-Print Network 3.0 - animal bacterial diseases Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

animal genetics. The information provided by the sequencing of the E. coli... for production of vaccines against enteric disease and to select traits in cattle that will reduce...

454

E-Print Network 3.0 - artery disease treated Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

diseases10 or tumor growth. In resistance arteries blood flow reduction... ). In rats treated with perindopril mean arterial ... Source: Ecole Polytechnique, Centre de...

455

E-Print Network 3.0 - animal disease transmission Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

Animal Disease F Fomite transmission 12;Vector transmission Anthrax... Webster on-line ... Source: Omiecinski, Curtis - Department of Veterinary and Biomedical Sciences,...

456

Perceived Threat of a Heart Attack among Mexican Americans with Cardiovascular Disease Risk.  

E-Print Network (OSTI)

??Compared to the general population, Mexican Americans are at greater risk for cardiovascular disease (CVD) events, such as heart attack, due to the high prevalence (more)

Florez, Elizabeth

2013-01-01T23:59:59.000Z

457

Modules, networks and systems medicine for understanding disease and aiding diagnosis  

Science Journals Connector (OSTI)

Mikael Benson and colleagues explain how and why systems medicine, and specifically network approaches, can be used to assist clinical decision making and identify underlying disease mechanisms

Mika Gustafsson; Colm E Nestor; Huan Zhang; Albert-Lszl Barabsi; Sergio Baranzini; Sren Brunak; Kian Chung; Howard J Federoff; Anne-Claude Gavin; Richard R Meehan; Paola Picotti; Miguel Pujana; Nikolaus Rajewsky; Kenneth Smith; Peter J Sterk; Pablo Villoslada; Mikael Benson

2014-10-17T23:59:59.000Z

458

E-Print Network 3.0 - artery disease increased Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

artery disease were related to stenotic lesions that could... a functional closure or "string sign". It is said that atretic internal thoracic ... Source: Technische...

459

Polycyclic aromatic hydrocarbons and fatal ischemic heart disease  

SciTech Connect

Several toxicologic and epidemiologic studies have produced evidence that occupational exposure to polycyclic aromatic hydrocarbons (PAH) is a risk factor for ischemic heart disease (IHD). However, a clear exposure-response relation has not been demonstrated. We studied a relation between exposure to PAH and mortality from IHD (418 cases) in a cohort of 12,367 male asphalt workers from Denmark, Finland, France, Germany, Israel, The Netherlands and Norway. Exposures to benzo(a)pyrene were assessed quantitatively using measurement-driven exposure models. Exposure to coal tar was assessed in a semiquantitative manner on the basis of information supplied by company representatives. We carried out sensitivity analyses to assess potential confounding by tobacco smoking. Both cumulative and average exposure indices for benzo(a)pyrene were positively associated with mortality from IHD. The highest relative risk for fatal IHD was observed for average benzo(a)pyrene exposures of 273 ng/m{sup 3} or higher, for which the relative risk was 1.64(95% confidence interval = 1.13-2.38). Similar results were obtained for coal tar exposure. Sensitivity analysis indicated that even in a realistic scenario of confounding by smoking, we would observe approximately 20% to 40% excess risk in IHD in the highest PAH-exposure categories. Our results lend support to the hypothesis that occupational PAH exposure causes fatal IHD and demonstrate a consistent exposure-response relation for this association.

Burstyn, I.; Kromhout, H.; Partanen, T.; Svane, O.; Langard, S.; Ahrens, W.; Kauppinen, T.; Stucker, I.; Shaham, J.; Heederik, D.; Ferro, G.; Heikkila, P.; Hooiveld, M.; Johansen, C.; Randem, B.G.; Boffetta, P. [International Agency for Research on Cancer, Lyon (France)

2005-11-01T23:59:59.000Z

460

Toxicological and pharmacological concerns on oxidative stress and related diseases  

SciTech Connect

Although reactive oxygen species (ROS) such as superoxide, hydrogen peroxide and hydroxyl radical are generated as the natural byproduct of normal oxygen metabolism, they can create oxidative damage via interaction with bio-molecules. The role of oxidative stress as a remarkable upstream part is frequently reported in the signaling cascade of inflammation as well as chemo attractant production. Even though hydrogen peroxide can control cell signaling and stimulate cell proliferation at low levels, in higher concentrations it can initiate apoptosis and in very high levels may create necrosis. So far, the role of ROS in cellular damage and death is well documented with implicating in a broad range of degenerative alterations e.g. carcinogenesis, aging and other oxidative stress related diseases (OSRDs). Reversely, it is cleared that antioxidants are potentially able to suppress (at least in part) the immune system and to enhance the normal cellular protective responses to tissue damage. In this review, we aimed to provide insights on diverse OSRDs, which are correlated with the concept of oxidative stress as well as its cellular effects that can be inhibited by antioxidants. Resveratrol, angiotensin converting enzyme inhibitors, angiotensin receptor blockers, statins, nebivolol and carvedilol, pentaerythritol tetranitrate, mitochondria-targeted antioxidants, and plant-derived drugs (alone or combined) are the potential medicines that can be used to control OSRD.

Saeidnia, Soodabeh [Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran 1417614411 (Iran, Islamic Republic of); College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon (Canada); Abdollahi, Mohammad, E-mail: Mohammad@TUMS.Ac.Ir [Department of Toxicology and Pharmacology, Faculty of Pharmacy, Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran 1417614411 (Iran, Islamic Republic of)

2013-12-15T23:59:59.000Z

Note: This page contains sample records for the topic "respiratory disease orthopedic" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


461

Inhibition of Host Cell Ribosomal Ribonucleic Acid Methylation by Foot-and-Mouth Disease Virus  

Science Journals Connector (OSTI)

...chromatography, which has a high resolving power for the nucleic acids (based on secondary...and J. Polatnick. 1968. The site of foot-and-mouth disease virus ribonucleic...and G. Vande Woude. 1966. Studies on foot-and-mouth disease virus ribonucleic...

Richard Ascione; George F. Vande Woude

1969-11-01T23:59:59.000Z

462

Modelling the initial spread of foot-and-mouth disease through animal movements  

Science Journals Connector (OSTI)

...stochastic nature of the epidemic process, its power for predicting the resultant epidemic size...and cattle experimentally infected with foot-and-mouth disease virus. J. Comp...S0021-9975(03)00045-8 . Anderson, I Foot mouth disease 2001: lessons to be learned...

2006-01-01T23:59:59.000Z

463

The role of pre-emptive culling in the control of foot-and-mouth disease  

Science Journals Connector (OSTI)

...the disease is introduced. foot-and-mouth|modelling...encephalopathy, classic swine fever and foot-and-mouth disease (FMD...veterinary inspectors were given the power to cull only parts of a holding...p s , p c , q s and q c are power-law parameters accounting...

2009-01-01T23:59:59.000Z

464

Integrating genetic and epidemiological data to determine transmission pathways of foot-and-mouth disease virus  

Science Journals Connector (OSTI)

...farms. The study has demonstrated the power of forensic genetic tracing for FMDV...Organization World Reference Laboratory for Foot-and-Mouth Disease. We are grateful...and cattle experimentally infected with foot-and-mouth disease virus O UK 2001...

2008-01-01T23:59:59.000Z

465

Degradation of Nuclear Factor Kappa B during Foot-and-Mouth Disease Virus Infection  

Science Journals Connector (OSTI)

...followed by 5 s of sonication at medium power in a Microsom XL2005 apparatus (Heat System...and C. A. Timpone. 1984. Epitopes on foot-and-mouth disease virus outer capsid...A region of the 5 noncoding region of foot-and-mouth disease virus RNA directs...

Teresa de los Santos; Fayna Diaz-San Segundo; Marvin J. Grubman

2007-09-19T23:59:59.000Z

466

A plasma signature of human mitochondrial disease revealed through metabolic profiling of spent media  

E-Print Network (OSTI)

A plasma signature of human mitochondrial disease revealed through metabolic profiling of spent culture with analysis of patient plasma to identify disease biomarkers. First, we applied global metabolic-defined metabolites in human plasma to discover that creatine is reproducibly elevated in two independent cohorts

Mootha, Vamsi K.

467

Information regarding Ebola Virus Disease (EVD) for Campus Personnel and Visitors September 5, 2014  

E-Print Network (OSTI)

Information regarding Ebola Virus Disease (EVD) for Campus Personnel and Visitors September 5, 2014 You are likely very much aware of the ongoing attention focused on the Ebola Virus Disease (EVD Control and Prevention (CDC) considers Ebola to pose little risk to persons in the U.S. at this time. We

Gerdes, J. Christian

468

Application of artificial neural network for detecting Phalaenopsis seedling diseases using color and texture features  

Science Journals Connector (OSTI)

In this study, we present an application of neural network and image processing techniques for detecting and classifying Phalaenopsis seedling diseases, including bacterial soft rot (BSR), bacterial brown spot (BBS), and Phytophthora black rot (PBR). ... Keywords: Color features, Image processing, Neural network, Phalaenopsis seedling diseases, Texture features, The adjustable exponential transform (AET)

Kuo-Yi Huang

2007-05-01T23:59:59.000Z

469

Integrating discretization and association rule-based classification for Alzheimer's disease diagnosis  

Science Journals Connector (OSTI)

This paper shows a computer aided diagnosis (CAD) combining continuous attribute discretization and association rule mining for the early diagnosis of Alzheimer's disease (AD) based on emission computed tomography images. A mask is obtained from the ... Keywords: Alzheimer's disease, Association rules, Computed aided diagnosis, Discretization, Image histogram

R. Chaves; J. RamRez; J. M. GRriz

2013-04-01T23:59:59.000Z

470

Asbestos-related diseases in automobile mechanics Jacques Ameille, MD1  

E-Print Network (OSTI)

1 Asbestos-related diseases in automobile mechanics Jacques Ameille, MD1 , Nicole Rosenberg, MD2-related diseases in automobile mechanics Corresponding author Jacques Ameille, MD, Unité de pathologie plaques, automobile mechanics, HRCT inserm-00671970,version1-20Feb2012 Author manuscript, published

Paris-Sud XI, Université de

471

"Red Sore Disease"in Game Fish1 Peggy Reed and Ruth Francis-Floyd2  

E-Print Network (OSTI)

VM85 "Red Sore Disease"in Game Fish1 Peggy Reed and Ruth Francis-Floyd2 1. This document is VM85 fish is generically referred to as "red sore disease." This problem usually occurs in the spring and fall, and fishermen and pond owners are often concerned by the appearance of red ulcers and sores

Watson, Craig A.

472

HOME GROUNDS & ANIMALS 2014 Home Fruit: Disease and Insects 3-1  

E-Print Network (OSTI)

HOME GROUNDS & ANIMALS 2014 Home Fruit: Disease and Insects 3-1 Disease and Insects Keith S. Yoder Pathologist, Alson H. Smith Jr. AREC Overview Growing fruits in the home orchard or garden can be an interesting and satisfying hobby, as well as a source of nutritious food for the home gardener. Tree fruits

Liskiewicz, Maciej

473

RESPONSE OF THE SWISS ALBINO MOUSE TO THE VIRUS OF NEWCASTLE DISEASE  

Science Journals Connector (OSTI)

...NEWCASTLE DISEASE Reginald L. Reagan A. L. Brueckner Maryland State Board of Agriculture...DISEASE REGINALD L. REAGAN AND A. L. BRUECKNER Maryland State Board of Agriculture...4-6 453 REGINALD L. REAGAN AND A. L. BRUECKNER used for the initial inoculum. Three-hundredths...

Reginald L. Reagan; A. L. Brueckner

1951-04-01T23:59:59.000Z

474

Modeling Economic Resilience and Animal Disease Outbreaks in the Texas High Plains  

E-Print Network (OSTI)

. Enhanced surveillance is found to be a preferred mitigation strategy for U.S. consumers in the scenario of smaller feedlot disease introductions (e.g. Large Beef Grazing and Backyard) and for U.S. producers in the larger feedlot disease introduction...

Lin, Hen-I

2012-02-14T23:59:59.000Z

475

Diagnosis of Annosus Root Disease in Mixed Conifer Forests in the Northwestern United States1  

E-Print Network (OSTI)

Diagnosis of Annosus Root Disease in Mixed Conifer Forests in the Northwestern United States1 Craig conifers are seldom damaged severely enough to cause a forest management concern. 1 Presented L. Schmitt 2 Abstract: Recognizing annosus root disease affecting conifers in northwestern United

Standiford, Richard B.

476

Distinct promoters regulate tissue-specific and differential expression of kallikrein 6 in CNS demyelinating disease  

E-Print Network (OSTI)

, and therein is regulated by injury. In the case of CNS demyelinating disease, K6 expression in CNS occurs in a tissue- specific fashion and are differentially regulated in response to CNS injury. While the human peripheral tissue. In a murine model of human CNS demyelinating inflammatory disease induced by Theiler's pi

Blaber, Michael

477

Modeling Disease Incidence Data with Spatial and Spatio-Temporal Dirichlet Process Mixtures  

E-Print Network (OSTI)

Modeling Disease Incidence Data with Spatial and Spatio-Temporal Dirichlet Process Mixtures approaches to analyze such data. We develop a hierarchical specification using spatial random effects modeled. Key words: Areal unit spatial data; Dirichlet process mixture models; Disease mapping; Dy- namic

Wolpert, Robert L

478

Scientists Probe Immune System's Role in Brain Function and Neurological Disease  

E-Print Network (OSTI)

Scientists Probe Immune System's Role in Brain Function and Neurological Disease Bridget M. Kuehn E in normal brain development and in the healthy adult brain. Studies also suggest that per- turbations of these roles may under- lie some neurological diseases. Contrary to dogma that the blood- brain barrier

Boulanger, Lisa

479

Lymphocystis Disease in Fish1 Roy P. E. Yanong, VMD2  

E-Print Network (OSTI)

FA181 Lymphocystis Disease in Fish1 Roy P. E. Yanong, VMD2 1. This document is FA181, one and marine fishes caused by infection with an iridovirus known as Lymphocystivirus or Lymphocystis disease does not cause significant mortalities, it does cause unsightly growths on fish that reduce

Watson, Craig A.

480

Health and Disease in East Africa Course Syllabus; Spring 2011 Interdisciplinary Perspectives on  

E-Print Network (OSTI)

Health and Disease in East Africa Course Syllabus; Spring 2011 1 Interdisciplinary Perspectives on Global Health and Disease: Uganda PHS 644: Section 30 Course Syllabus ­ Spring 2012 Wednesdays 5 Prerequisites: Graduate and health professional students who plan field study in Uganda and/or East Africa

Sheridan, Jennifer

Note: This page contains sample records for the topic "respiratory disease orthopedic" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


481

Home Monitoring of Oxygen Saturation and Symptoms for Sickle Cell Disease  

E-Print Network (OSTI)

Home Monitoring of Oxygen Saturation and Symptoms for Sickle Cell Disease Introduction and Aims There is evidence that the vaso-occlusive crises and other complications associated with sickle cell disease (SCD oxygen levels and the onset of sickle cell crises. A secondary objective of the study is to investigate

Oakley, Jeremy

482

An advanced visualization system for the neurofunctional study of Parkinson's disease  

Science Journals Connector (OSTI)

Understanding of anatomy and spatial relationships of affected brain structures in Parkinson's disease and movement pathways remains a challenge for healthcare students. This paper aims to provide an interactive digital tool to enhance the study of the ... Keywords: Parkinson's disease, medical training, software

Juan A. Juanes, Pablo Ruisoto, Jos A. Obeso, Joan San-Molina, Alberto Prats

2014-10-01T23:59:59.000Z

483

Real-Time Disease Surveillance Using Twitter Data: Demonstration on Flu and Cancer  

E-Print Network (OSTI)

, and text mining. The real-time analysis data is visually re- ported as U.S. disease activity map, timelinesReal-Time Disease Surveillance Using Twitter Data: Demonstration on Flu and Cancer Kathy Lee Ankit-effects, and so on. This makes publicly available social media data an invaluable resource for mining interesting

484

A medical game changer New device shows early promise for detecting heart disease  

E-Print Network (OSTI)

Fall 2012 A medical game changer New device shows early promise for detecting heart disease It as a functional test for people at high risk of developing heart disease, the leading cause of death in the United for enhancing auscultation (listening to heart sounds). Her husband, Robert Guion, was a convenient, good

Minnesota, University of

485

Coronary Heart Disease: Overview #1 Killer in the U.S.  

E-Print Network (OSTI)

#12;Coronary Heart Disease: Overview · #1 Killer in the U.S. · Accounts for more than one in five, the vessels that supply the heart · Disease process: coronary atherosclerosis (plagues in artery) involves flow, shortage of oxygen, pain that radiates across the chest and arms Myocardial infarction - heart

Meagher, Mary

486

U.S. Department of Health And Human Services Centers for Disease Control and Prevention  

E-Print Network (OSTI)

is a dangerous situation that can bring on health emergencies in susceptible people, such as those withoutU.S. Department of Health And Human Services Centers for Disease Control and Prevention #12;For more information on cold weather conditions and health, please contact: Centers for Disease Control

Khan, Javed I.

487

UPDATE ON THE POTATO PURPLE TOP DISEASE IN THE COLUMBIA BASIN J.E. MUNYANEZA1  

E-Print Network (OSTI)

UPDATE ON THE POTATO PURPLE TOP DISEASE IN THE COLUMBIA BASIN J.E. MUNYANEZA1 , J.M. CROSSLIN2 , A Washington State Potato Commission, Moses Lake, WA; 4 Oregon State University, Hermiston, OR; 5 Washington on the potato purple top disease in the Columbia Basin. In: Proceedings, 44th Annual Washington State Potato

Pappu, Hanu R.

488

GIS-Based Epidemiological Modeling of an Emerging Forest Disease: Spread of  

E-Print Network (OSTI)

247 GIS-Based Epidemiological Modeling of an Emerging Forest Disease: Spread of Sudden Oak Death applied in a GIS to real-world wildland landscapes. In this paper, we present and evaluate a GIS model was implemented (1990-2005) in a GIS to simulate disease spread across California at a spatial

Standiford, Richard B.

489

Gout and Parkinson's Disease in Older People: An Observation in Taiwan  

Science Journals Connector (OSTI)

Summary The goal of this study was to investigate the association between gout and Parkinson's disease in older people in Taiwan. Utilizing the Taiwan National Health Insurance database, this casecontrol study included 3854 patients aged 65 years or older with newly diagnosed Parkinson's disease as the case group [mean age 75.0 years and standard deviation (SD) 5.0 years], and 15,416 patients without Parkinson's disease as the control group (mean age 74.0 years and SD 5.3 years). Multivariable logistic regression analysis detected no association between gout and Parkinson's disease in both sex [odds ratio (OR)= 0.98, 95% confidence interval (CI)= 0.861.12, in men and OR= 1.03, 95% CI= 0.881.21, in women, respectively]. We conclude that no association can be detected between gout and Parkinson's disease in older people in Taiwan.

Shih-Wei Lai; Chih-Hsueh Lin; Cheng-Li Lin; Kuan-Fu Liao

2014-01-01T23:59:59.000Z

490

Health Detectives: Uncovering the Mysteries of Disease (LBNL Science at the Theater)  

ScienceCinema (OSTI)

In this April 23, 2012 Science at the Theater event, Berkeley Lab scientists discuss how they uncover the mysteries of disease in unlikely places. Speakers and topics include: World-renowned cancer researcher Mina Bissell's pioneering research on the role of the cellular microenvironment in breast cancer has changed the conversation about the disease. How does DNA instability cause disease? To find out, Christie Canaria images neural networks to study disorders such as Huntington's disease. Fruit flies can tell us a lot about ourselves. Susan Celniker explores the fruit fly genome to learn how our genome works. DNA is not destiny. Gary Karpen explores how environmental factors shape genome function and disease through epigenetics.

Bissell, Mina; Canaria, Christie; Celnicker, Susan; Karpen, Gary

2014-05-06T23:59:59.000Z

491

Delays in Reducing Waterborne and Water-related Infectious Diseases in China under Climate Change  

SciTech Connect

Despite Chinas rapid progress improving water, sanitation and hygiene (WSH) infrastructure and access, in 2011, 471 million people lacked access to improved sanitation, and 401 million people lacked access to household piped water. Infectious diseases are sensitive to changes in climate, particularly temperature, and WSH conditions. To explore possible impacts of climate change on these diseases in China in 2020 and 2030, we coupled estimates of the temperature sensitivity of diarrheal disease and three vector-borne diseases, temperature projections from global climate models using four emissions pathways, WSH-infrastructure development scenarios and projected demographic changes. By 2030, the projected impacts would delay Chinas historically rapid progress toward reducing the burden of WSH-attributable infectious disease by 8-85 months. This developmental delay provides a key summary measure of the impact of climate change in China, and in other societies undergoing rapid social, economic, and environmental change.

Hodges, Maggie; Belle, Jessica; Carlton, Elizabeth; Liang, Song; Li, Huazhong; Luo, Wei; Freeman, Matthew C.; Liu, Yang; Gao, Yang; Hess, Jeremy; Remais, Justin V.

2014-12-01T23:59:59.000Z

492

Alcohol consumption, Lewis phenotypes, and risk of ischemic heart disease  

SciTech Connect

The authors have previously found an increased risk of ischemic heart disease (IHD) in men with the Lewis phenotype Le(a[minus]b[minus]) and suggested that the Lewis blood group has a close genetic relation with insulin resistance. The authors have investigated whether any conventional risk factors explain the increased risk in Le(a[minus]b[minus]) men. 3,383 men aged 53-75 years were examined in 1985-86, and morbidity and mortality during the next 4 years were recorded. At baseline, the authors excluded 343 men with a history of myocardial infarction, angina pectoris, intermittent claudication, or stroke. The potential risk factors examined were alcohol consumption, physical activity, tobacco smoking, serum cotinine, serum lipids, body-mass index, blood pressure, prevalence of hypertension and non-insulin-dependent diabetes mellitus, and social class. In 280 (9.6%) men with Le(a[minus]b[minus]), alcohol was the only risk factor significantly associated with risk of IHD. There was a significant inverse dose-effect relation between alcohol consumption and risk; trend tests, with adjustment for age, were significant for fatal IHD (p=0.02), all IHD (p=0.03), and all causes of death (p=0.02). In 2649 (90.4%) men with other phenotypes, there was a limited negative association with alcohol consumption. In Le(a[minus]b[minus]) men, a group genetically at high risk of IHD, alcohol consumption seems to be especially protective. The authors suggest that alcohol consumption may modify insulin resistance in Le(a[minus]b[minus]) men.

Hein, H.O.; Suadicani, P.; Gyntelberg, F. (Rigshospitalet State Univ. Hospital, Copenhagen (Denmark). Epidemiological Research Unit); Sorenson, H. (Rigshospitalet State Univ. Hospital, Copenhagen (Denmark). Dept. of Chemical Immunology); Hein, H.O. (Univ. of Copenhagen (Denmark). Dept. of Internal Medicine)

1993-02-13T23:59:59.000Z

493

Heart DiseaseHeart Disease--Learn to Love YourLearn to Love Your Michael McKee, M.D.Michael McKee, M.D.  

E-Print Network (OSTI)

Heart DiseaseHeart Disease-- Learn to Love YourLearn to Love Your HeartHeart Michael McKee, M.D.Michael McKee, M.D. March 19, 2010March 19, 2010 #12;GoalsGoals ·· Learn more about heart disease for yourself andLearn more about heart disease for yourself and for your studentsfor your students ·· Learn

Goldman, Steven A.

494

The effects of Bordetella pertussis on dendritic cell imprinting of CD4+ T cells.  

E-Print Network (OSTI)

?? Bordetella pertussis is an aerobic gram-negative bacterial pathogen that causes the human respiratory disease whooping cough. Despite widespread vaccination, whooping cough is reemerging due (more)

Waheed, Sana

2010-01-01T23:59:59.000Z

495

E-Print Network 3.0 - aging dietary restriction Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

intake and the incidence of respiratory diseases, especially chronic... composition database, and divided into quintiles. After adjustment for 11 factors (age, sex, smoking,...

496

Email Template  

NLE Websites -- All DOE Office Websites (Extended Search)

Ken said DOE and WRPS continue to participate in site-wide safety programs, including lockout and tagout, the Chronic Beryllium Disease (CBD) Prevention Program, respiratory...

497

A double-blind, randomized, multicenter phase 2 study of prasugrel versus placebo in adult patients with sickle cell disease  

E-Print Network (OSTI)

in adult patients with sickle cell disease. Journal of1. Steinberg MH: Management of sickle cell disease. N Engl Jadherence to endothelium in sickle-cell anemia. A possible

2013-01-01T23:59:59.000Z

498

Plaque Formation and Progression in Atherosclerosis, and Inflammation and Stroke in Sickle Cell Disease - Does Chlamydia Pneumoniae Play a Role?  

E-Print Network (OSTI)

30) E. The Pathogenesis of Sickle Cell Disease (p. 33) 1. 2.ammation and Stroke in Sickle Cell Disease Does Chlamydiastroke prevention trial in sickle cell anemia (STOP) study.

Schwab-Doyle, Felicia V

2003-01-01T23:59:59.000Z

499

Advanced hepatic fibrosis and cirrhosis due to nonalcoholic fatty liver disease in Sri Lankan children: a preliminary report  

Science Journals Connector (OSTI)

Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases and may progress to advanced hepatic fibrosis and cirrhosis in some patients. Cirrhosis due to NAFLD is considered extr...

S. Rajindrajith; A. S. Dassanayake; J. Hewavisenthi

2008-06-01T23:59:59.000Z

500

Normalization of Plasma 25-Hydroxy Vitamin D Is Associated with Reduced Risk of Surgery in Crohns Disease  

E-Print Network (OSTI)

AB Background: Vitamin D may have an immunologic role in Crohn's disease (CD) and ulcerative colitis (UC). Retrospective studies suggested a weak association between vitamin D status and disease activity but have significant ...

Ananthakrishnan, Ashwin N.