National Library of Energy BETA

Sample records for regulated lead acid

  1. DOE specification: Valve-regulated type lead-acid storage batteries

    SciTech Connect (OSTI)

    1996-08-01

    This document contains a ``fill-in-the-blanks`` guide specification for procurement of sealed valve-regulated type lead-acid storage batteries, for uninterruptible power supply applications.

  2. DOE-SPEC-3019-96; Valve-Regulated Type Lead-Acid Storage Batteries

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    9-96 August 1996 DOE SPECIFICATION VALVE-REGULATED TYPE LEAD-ACID STORAGE BATTERIES U.S. Department of Energy FSC 6140 Washington, D.C. 20585 DISTRIBUTION STATEMENT A. Approved for public release; distribution is unlimited. This document has been reproduced directly from the best available copy. Available to DOE and DOE contractors from the Office of Scientific and Technical Information, P.O. Box 62, Oak Ridge, TN 37831; (423) 576-8401. Available to the public from the U.S. Department of

  3. Reliability of valve-regulated lead-acid batteries for stationary applications.

    SciTech Connect (OSTI)

    De Anda, Mindi Farber; Butler, Paul Charles; Miller, Jennifer L; Moseley, Patrick T.

    2004-03-01

    A survey has been carried out to quantify the performance and life of over 700,000 valve-regulated lead-acid (VRLA) cells, which have been or are being used in stationary applications across the United States. The findings derived from this study have not identified any fundamental flaws of VRLA battery technology. There is evidence that some cell designs are more successful in float duty than others. A significant number of the VRLA cells covered by the survey were found to have provided satisfactory performance.

  4. Sandia National Laboratories: Due Diligence on Lead Acid Battery...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Due Diligence on Lead Acid Battery Recycling March 23, 2011 Lead Acid Batteries on secondary containment pallet Lead Acid Batteries on secondary containment pallet In 2004, the US...

  5. Primer on lead-acid storage batteries

    SciTech Connect (OSTI)

    1995-09-01

    This handbook was developed to help DOE facility contractors prevent accidents caused during operation and maintenance of lead-acid storage batteries. Major types of lead-acid storage batteries are discussed as well as their operation, application, selection, maintenance, and disposal (storage, transportation, as well). Safety hazards and precautions are discussed in the section on battery maintenance. References to industry standards are included for selection, maintenance, and disposal.

  6. Lightweight, durable lead-acid batteries

    DOE Patents [OSTI]

    Lara-Curzio, Edgar; An, Ke; Kiggans, Jr., James O; Dudney, Nancy J; Contescu, Cristian I; Baker, Frederick S; Armstrong, Beth L

    2013-05-21

    A lightweight, durable lead-acid battery is disclosed. Alternative electrode materials and configurations are used to reduce weight, to increase material utilization and to extend service life. The electrode can include a current collector having a buffer layer in contact with the current collector and an electrochemically active material in contact with the buffer layer. In one form, the buffer layer includes a carbide, and the current collector includes carbon fibers having the buffer layer. The buffer layer can include a carbide and/or a noble metal selected from of gold, silver, tantalum, platinum, palladium and rhodium. When the electrode is to be used in a lead-acid battery, the electrochemically active material is selected from metallic lead (for a negative electrode) or lead peroxide (for a positive electrode).

  7. Lightweight, durable lead-acid batteries

    SciTech Connect (OSTI)

    Lara-Curzio, Edgar; An, Ke; Kiggans, Jr., James O.; Dudney, Nancy J.; Contescu, Cristian I.; Baker, Frederick S.; Armstrong, Beth L.

    2011-09-13

    A lightweight, durable lead-acid battery is disclosed. Alternative electrode materials and configurations are used to reduce weight, to increase material utilization and to extend service life. The electrode can include a current collector having a buffer layer in contact with the current collector and an electrochemically active material in contact with the buffer layer. In one form, the buffer layer includes a carbide, and the current collector includes carbon fibers having the buffer layer. The buffer layer can include a carbide and/or a noble metal selected from of gold, silver, tantalum, platinum, palladium and rhodium. When the electrode is to be used in a lead-acid battery, the electrochemically active material is selected from metallic lead (for a negative electrode) or lead peroxide (for a positive electrode).

  8. Advanced Lead Acid Battery Consortium | Open Energy Information

    Open Energy Info (EERE)

    Lead Acid Battery Consortium Jump to: navigation, search Name: Advanced Lead-Acid Battery Consortium Place: Durham, North Carolina Zip: 27713 Sector: Vehicles Product: The ALABC is...

  9. Closure device for lead-acid batteries

    DOE Patents [OSTI]

    Ledjeff, Konstantin

    1983-01-01

    A closure device for lead-acid batteries includes a filter of granulated activated carbon treated to be hydrophobic combined with means for preventing explosion of emitted hydrogen and oxygen gas. The explosion prevention means includes a vertical open-end tube within the closure housing for maintaining a liquid level above side wall openings in an adjacent closed end tube. Gases vent from the battery through a nozzle directed inside the closed end tube against an impingement surface to remove acid droplets. The gases then flow through the side wall openings and the liquid level to quench any possible ignition prior to entering the activated carbon filter. A wick in the activated carbon filter conducts condensed liquid back to the closure housing to replenish the liquid level limited by the open-end tube.

  10. Sandia National Laboratories: Due Diligence on Lead Acid Battery Recycling

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Due Diligence on Lead Acid Battery Recycling March 23, 2011 Lead Acid Batteries on secondary containment pallet Lead Acid Batteries on secondary containment pallet In 2004, the US Geological Survey estimated that 95% of lead in the United States is recycled, primarily from used lead acid batteries. A broader 2009 European study estimated that globally about 52% of lead is recycled, and a 2008 Asian study estimated a global recycle rate of 68%. Unfortunately, many incidents over the past decade

  11. DOE specification: Flooded-type lead-acid storage batteries

    SciTech Connect (OSTI)

    1996-08-01

    This document contains a ``fill-in-the-blanks`` guide specification for procurement of flooded-type lead-acid storage batteries, for uninterruptible power supply applications.

  12. Anaerobic microbial dissolution of lead and production of organic acids

    DOE Patents [OSTI]

    Francis, A.J.; Dodge, C.; Chendrayan, K.; Quinby, H.L.

    1987-04-16

    The present invention related to an anaerobic bacterial culture of Clostridium sp. ATCC No. 53464 which solubilizes lead oxide under anaerobic conditions in coal and industrial wastes and therefore presents a method of removing lead from such wastes before they are dumped into the environment. The rat of lead dissolution during logarithmic growth of the bacteria in 40 ml medium containing 3.32 ..mu..moles of lead as lead oxide was 0.042 ..mu..moles m1/sup /-/1/ hr/sup /-/1/. Dissolution of lead oxide by the bacterial isolate is due to the production of metabolites and acidity in the culture medium. The major metabolites are acetic, butyric and lactic acid. The major metabolites are acetic, butyric and lactic acid. Clostridium sp. ATCC No. 53464 can be used in the recovery of the strategic metals from ores and wastes and also for the production of lactic acid for commercial purposes. The process yields large quantities of lactic acid as well as lead complexed in a stable form with said acids. 4 figs., 3 tabs.

  13. Anaerobic microbial dissolution of lead and production of organic acids

    DOE Patents [OSTI]

    Francis, Arokiasamy J.; Dodge, Cleveland; Chendrayan, Krishnachetty; Quinby, Helen L.

    1988-01-01

    The present invention relates to an anaerobic bacterial culture of Clostridium sp. ATCC No. 53464 which solubilizes lead oxide under anaerobic conditions in coal and industrial wastes and therefore presents a method of removing lead from such wastes before they are dumped into the environment. The rate of lead dissolution during logarithmic growth of the bacteria in 40 ml medium containing 3.32 .mu.moles of lead as lead oxide was 0.042 .mu.moles ml.sup.-1 hr.sup.-1. Dissolution of lead oxide by the bacterial isolate is due to the production of metabolites and acidity in the culture medium. The major metabolites are acetic, butyric and lactic acid. Clostridium sp. ATCC No. 53464 can be used in the recovery of strategic metals from ores and wastes and also for the production of lactic acid for commercial purposes. The process yields large quantities of lactic acid as well as lead complexed in a stable form with said acids.

  14. System for agitating the acid in a lead-acid battery

    DOE Patents [OSTI]

    Weintraub, Alvin; MacCormack, Robert S.

    1987-01-01

    A system and method for agitating the acid in a large lead-sulfuric acid storage battery of the calcium type. An air-lift is utilized to provide the agitation. The air fed to the air-lift is humidified prior to being delivered to the air-lift.

  15. Anaerobic microbial dissolution of lead and production of organic acids

    DOE Patents [OSTI]

    Francis, A.J.; Dodge, C.; Chendrayan, K.

    1986-02-28

    The present invention relates to a method of solubilizing lead, in the form of lead oxide, found in industrial wastes, before these wastes are dumped into the environment. The lead is solubilized by dissolving the lead oxide in the wastes through contact with an anaerobic bacterial culture containing the bacterium ATCC No. 53464. The solubilized lead can then be removed from the wastes by chemical separation. It could also be removed by extending the contact period with the bacterial culture. As the culture grows, the solubilized lead is removed from the wastes by bioaccumulation by the microorganism or by immobilization by a polymer-like material produced by the microorganism. At this point, the lead is then removed from the wastes when the waste material is separated from the bacterial culture. If desired, the bacterial culture could be digested at this point to yield relatively pure lead for further industrial use.

  16. Regulating for the long term: SMCRA and acid mine drainage

    SciTech Connect (OSTI)

    Shea, C.W.

    1995-12-31

    With the passage of the Surface Mining Control and Reclamation Act of 1977 (SMCRA), regulators and industry representatives expected to solve the problem of pollution of the Nation`s waterways caused by acidic discharges from coal mines. Eighteen years after the passage of SMCRA, hard issues of predicting, regulating and treating acid mine drainage remain. Acid mine drainage is most common in the coal seams of the Midwest and Appalachia: Pennsylvania, West Virginia, Maryland, Ohio, Illinois, and Tennessee. This article discusses regulation of coal mines and acid mine drainage for the long term.

  17. Mutations in global regulators lead to metabolic selection during adaptation to complex environments

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Saxer, Gerda; Krepps, Michael D.; Merkley, Eric D.; Ansong, Charles; Deatherage Kaiser, Brooke L.; Valovska, Marie -Thérèse; Ristic, Nikola; Yeh, Ping T.; Prakash, Vittal P.; Leiser, Owen P.; et al

    2014-12-11

    Adaptation to ecologically complex environments can provide insights into the evolutionary dynamics and functional constraints encountered by organisms during natural selection. Unlike adaptation to a single limiting resource, adaptation to a new environment with abundant and varied resources can be difficult to achieve by small incremental changes since many mutations are required to achieve even modest gains in fitness. Since changing complex environments are quite common in nature, we investigated how such an epistatic bottleneck can be avoided to allow rapid adaptation. We show that adaptive mutations arise repeatedly in independently evolved populations in the context of greatly increased geneticmore » and phenotypic diversity. We go on to show that weak selection requiring substantial metabolic reprogramming can be readily achieved by mutations in the global response regulator arcA and the stress response regulator rpoS. We identified 46 unique single-nucleotide variants of arcA and 18 mutations in rpoS, nine of which resulted in stop codons or large deletions, suggesting that a subtle modulation of ArcA function and knockouts of rpoS are largely responsible for the metabolic shifts leading to adaptation. These mutations allow a higher order “metabolic selection” that eliminates epistatic bottlenecks, which could occur when many changes would be required. Proteomic and carbohydrate analysis of adapting E. coli populations revealed an up-regulation of enzymes associated with the TCA cycle and amino acid metabolism and an increase in the secretion of putrescine. The overall effect of adaptation across populations is to redirect and efficiently utilize uptake and catabolism of abundant amino acids. Concomitantly, there is a pronounced spread of more ecologically limited strains that results from specialization through metabolic erosion. Remarkably, the global regulators arcA and rpoS can provide a “one-step” mechanism of adaptation to a novel

  18. Fact Sheet: Carbon-Enhanced Lead-Acid Batteries (October 2012) | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of Energy Carbon-Enhanced Lead-Acid Batteries (October 2012) Fact Sheet: Carbon-Enhanced Lead-Acid Batteries (October 2012) DOE's Energy Storage Program is funding research and testing to improve the performance and reduce the cost of lead-acid batteries. Research to understand and quantify the mechanisms responsible for the beneficial effect of carbon additions will help demonstrate the near-term feasibility of grid-scale energy storage with lead-acid batteries, and may also benefit other

  19. Fact Sheet: Carbon-Enhanced Lead-Acid Batteries (October 2012...

    Office of Environmental Management (EM)

    In 1997, researchers made two important advancements to lead-acid batteries. First, the Japan Storage Battery Company showed that adding carbon to the battery dramatically reduces ...

  20. Lead-acid battery companies join forces with Argonne National Laboratory to

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    enhance battery performance | Argonne National Laboratory Lead-acid battery companies join forces with Argonne National Laboratory to enhance battery performance September 1, 2016 Tweet EmailPrint Exploring the unrealized potential of lead batteries is the goal of a new collaboration between the U.S. Department of Energy's Argonne National Laboratory and two leading lead recycling and lead battery manufacturing companies, RSR Technologies and East Penn Manufacturing. The collaboration will

  1. Mutations in global regulators lead to metabolic selection during adaptation to complex environments

    SciTech Connect (OSTI)

    Saxer, Gerda; Krepps, Michael D.; Merkley, Eric D.; Ansong, Charles; Deatherage Kaiser, Brooke L.; Valovska, Marie -Thérèse; Ristic, Nikola; Yeh, Ping T.; Prakash, Vittal P.; Leiser, Owen P.; Nakhleh, Luay; Gibbons, Henry S.; Kreuzer, Helen W.; Shamoo, Yousif; Matic, Ivan

    2014-12-11

    Adaptation to ecologically complex environments can provide insights into the evolutionary dynamics and functional constraints encountered by organisms during natural selection. Unlike adaptation to a single limiting resource, adaptation to a new environment with abundant and varied resources can be difficult to achieve by small incremental changes since many mutations are required to achieve even modest gains in fitness. Since changing complex environments are quite common in nature, we investigated how such an epistatic bottleneck can be avoided to allow rapid adaptation. We show that adaptive mutations arise repeatedly in independently evolved populations in the context of greatly increased genetic and phenotypic diversity. We go on to show that weak selection requiring substantial metabolic reprogramming can be readily achieved by mutations in the global response regulator arcA and the stress response regulator rpoS. We identified 46 unique single-nucleotide variants of arcA and 18 mutations in rpoS, nine of which resulted in stop codons or large deletions, suggesting that a subtle modulation of ArcA function and knockouts of rpoS are largely responsible for the metabolic shifts leading to adaptation. These mutations allow a higher order “metabolic selection” that eliminates epistatic bottlenecks, which could occur when many changes would be required. Proteomic and carbohydrate analysis of adapting E. coli populations revealed an up-regulation of enzymes associated with the TCA cycle and amino acid metabolism and an increase in the secretion of putrescine. The overall effect of adaptation across populations is to redirect and efficiently utilize uptake and catabolism of abundant amino acids. Concomitantly, there is a pronounced spread of more ecologically limited strains that results from specialization through metabolic erosion. Remarkably, the global regulators arcA and rpoS can provide a

  2. DOE-SPEC-3018-96; Flooded-Type Lead-Acid Storage Batteries

    Broader source: Energy.gov (indexed) [DOE]

    DOE SPECIFICATION FLOODED-TYPE LEAD-ACID STORAGE BATTERIES U.S. Department of Energy FSC 6140 Washington, ... proposal &21; Appendix B: Battery system data sheets to be completed by ...

  3. Delta-aminolevulinic acid dehydratase (ALAD) polymorphism in lead exposed Bangladeshi children and its effect on urinary aminolevulinic acid (ALA)

    SciTech Connect (OSTI)

    Tasmin, Saira; Furusawa, Hana; Ahmad, Sk. Akhtar; Watanabe, Chiho

    2015-01-15

    Background and objective: Lead has long been recognized as a harmful environmental pollutant. People in developing countries like Bangladesh still have a higher risk of lead exposure. Previous research has suggested that the delta-aminolevulinic acid dehydratase (ALAD) genotype can modify lead toxicity and individual susceptibility. As children are more susceptible to lead-induced toxicity, this study investigated whether the ALAD genotype influenced urinary excretion of delta-aminolevulinic acid (U-ALA) among children exposed to environmental lead in Bangladesh. Methods: Subjects were elementary schoolchildren from a semi-urban industrialized area in Bangladesh. A total of 222 children were studied. Blood and urine were collected to determine ALAD genotypes, blood lead levels and urinary aminolevulinic acid (U-ALA). Results: The mean BPb level was 9.7 µg/dl for the study children. BPb was significantly positively correlated with hemoglobin (p<0.01). In total, allele frequency for ALAD 1 and 2 was 0.83 and 0.17 respectively. The mean U-ALA concentration was lower in ALAD1-2/2-2 carriers than ALAD1-1 carriers for boys (p=0.001). But for girls, U-ALA did not differ significantly by genotype (p=0.26). When U-ALA was compared by genotype at the same exposure level in a multiple linear regression analysis, boys who were ALAD1-2/2-2 carriers still had a lower level of U-ALA compared to ALAD1-1carriers. Conclusion: This study provides information about the influence of ALAD polymorphism and its association with U-ALA in Bangladeshi children. Our results indicate that the ALAD1-2/2-2 genotype may have a protective effect in terms of U-ALA for environmentally lead exposed boys. - Highlights: • High blood lead level for the environmentally exposed schoolchildren. • BPb was significantly correlated with U-ALA and Hb. • Effect of ALAD genotype on U-ALA is differed by sex. • Lower U-ALA in ALAD2 than ALAD1 carriers only for boys at same exposure.

  4. Electric and hybrid vehicles charge efficiency tests of ESB EV-106 lead-acid batteries

    SciTech Connect (OSTI)

    Rowlette, J.J.

    1981-01-15

    Charge efficiencies were determined for ESB EV-106 lead-acid batteries by measurements made under widely differing conditions of temperature, charge procedure, and battery age. The measurements were used to optimize charge procedures and to evaluate the concept of a modified, coulometric state-of-charge indicator. Charge efficiency determinations were made by measuring gassing rates and oxygen fractions. A novel, positive displacement gas flow meter which proved to be both simple and highly accurate is described and illustrated.

  5. Lead-based paint and lead-containing materials: The impact of recent EPA and OSHA regulations on maintenance and construction

    SciTech Connect (OSTI)

    Staker, R.D.; Scheffius, F.R.

    1998-07-01

    Over the past several years a number of new federal environmental, health, and safety regulations have been established which address various types of lead containing materials such as lead used in solder and lead-based paint. The regulations pertain to the use, removal, disposal, and handling of lead-containing materials during maintenance activities, renovation activities, and new construction. This paper will present a review of these new regulations, the impact on and applicability to maintenance and construction activities, and the risks to human health and environment. Examples will be used to illustrate the concepts discussed. This paper should be of particular interest to electric power senior managers, plant managers, environmental managers, and environmental staff.

  6. Epigenetic regulation leading to induced pluripotency drives cancer development in vivo

    SciTech Connect (OSTI)

    Ohnishi, Kotaro; Semi, Katsunori; Yamada, Yasuhiro

    2014-12-05

    Highlights: • Epigenetic regulation of failed reprogramming-associated cancer cells is discussed. • Similarity between pediatric cancer and reprogramming-associated cancer is discussed. • Concept for epigenetic cancer is discussed. - Abstract: Somatic cells can be reprogrammed into induced pluripotent stem cells (iPSCs) by the transient expression of reprogramming factors. During the reprogramming process, somatic cells acquire the ability to undergo unlimited proliferation, which is also an important characteristic of cancer cells, while their underlying DNA sequence remains unchanged. Based on the characteristics shared between pluripotent stem cells and cancer cells, the potential involvement of the factors leading to reprogramming toward pluripotency in cancer development has been discussed. Recent in vivo reprogramming studies provided some clues to understanding the role of reprogramming-related epigenetic regulation in cancer development. It was shown that premature termination of the in vivo reprogramming result in the development of tumors that resemble pediatric cancers. Given that epigenetic modifications play a central role during reprogramming, failed reprogramming-associated cancer development may have provided a proof of concept for epigenetics-driven cancer development in vivo.

  7. AVTA: 2010 Honda Civic HEV with Experimental Ultra Lead Acid Battery Testing Results

    Office of Energy Efficiency and Renewable Energy (EERE)

    The Vehicle Technologies Office's Advanced Vehicle Testing Activity carries out testing on a wide range of advanced vehicles and technologies on dynamometers, closed test tracks, and on-the-road. These results provide benchmark data that researchers can use to develop technology models and guide future research and development. The following reports describe results of testing done on a 2010 Civic hybrid electric vehicle with an advanced experimental ultra-lead acid battery, an experimental vehicle not for sale. The baseline performance testing provides a point of comparison for the other test results. Taken together, these reports give an overall view of how this vehicle functions under extensive testing. This research was conducted by Idaho National Laboratory.

  8. Field Operations Program Chevrolet S-10 (Lead-Acid) Accelerated Reliability Testing - Final Report

    SciTech Connect (OSTI)

    J. Francfort; J. Argueta; M. Wehrey; D. Karner; L. Tyree

    1999-07-01

    This report summarizes the Accelerated Reliability testing of five lead-acid battery-equipped Chevrolet S-10 electric vehicles by the US Department of Energy's Field Operations Program and the Program's testing partners, Electric Transportation Applications (ETA) and Southern California Edison (SCE). ETA and SCE operated the S-10s with the goal of placing 25,000 miles on each vehicle within 1 year, providing an accelerated life-cycle analysis. The testing was performed according to established and published test procedures. The S-10s' average ranges were highest during summer months; changes in ambient temperature from night to day and from season-to-season impacted range by as much as 10 miles. Drivers also noted that excessive use of power during acceleration also had a dramatic effect on vehicle range. The spirited performance of the S-10s created a great temptation to inexperienced electric vehicle drivers to ''have a good time'' and to fully utilize the S-10's acceleration capability. The price of injudicious use of power is greatly reduced range and a long-term reduction in battery life. The range using full-power accelerations followed by rapid deceleration in city driving has been 20 miles or less.

  9. WPN 02-6: Weatherization Activities and Federal Lead-Based Paint Regulations

    Office of Energy Efficiency and Renewable Energy (EERE)

    Replaces WPN 01-10 issued May 10, 2001, and provides updated guidance to regional offices and states relative to weatherization health and safety matters associated with lead-based paint in homes.

  10. Epidemiological-environemental study of lead acid battery workers. III. Chronic effects of sulfuric acid on the respiratory system and teeth

    SciTech Connect (OSTI)

    Gamble, J.; Jones, W.; Hancock, J.; Meckstroth, R.L.

    1984-10-01

    The effects of long-term exposure to sulfuric acid mist on the teeth and respiratory system were studied in 248 workers in five plants manufacturing lead acid batteries. The prevalence of cough, phlegm, dyspnea, and wheezing as determined by questionnaire were not associated with estimates of cumulative acid exposure. There was only one case of irregular opacities seen on the chest radiographs. There was no statistically significant association of reduced FEV/sub 1/ peak flow, FEF/sub 50/, and FEF/sub 75/ with acid exposure although the higher exposed group had lower mean values. FVC in the high exposure group showed a statistically significant reductioon compared to the low exposure group but there was no significant association when exposure was analyzed as a continuous variable. The ratio of observed to expected prevalence of teeth etching and erosion was about four times greater in the high acid-exposure group. The earliest case of etching occured after 4 months exposure to an estimated average exposure of 0.23 mg/m/sup 3/ sulfuric acid.

  11. Leading trends in environmental regulation that affect energy development. Final report

    SciTech Connect (OSTI)

    Steele, R V; Attaway, L D; Christerson, J A; Kikel, D A; Kuebler, J D; Lupatkin, B M; Liu, C S; Meyer, R; Peyton, T O; Sussin, M H

    1980-01-01

    Major environmental issues that are likely to affect the implementation of energy technologies between now and the year 2000 are identified and assessed. The energy technologies specifically addressed are: oil recovery and processing; gas recovery and processing; coal liquefaction; coal gasification (surface); in situ coal gasification; direct coal combustion; advanced power systems; magnetohydrodynamics; surface oil shale retorting; true and modified in situ oil shale retorting; geothermal energy; biomass energy conversion; and nuclear power (fission). Environmental analyses of these technologies included, in addition to the main processing steps, the complete fuel cycle from resource extraction to end use. A comprehensive survey of the environmental community (including environmental groups, researchers, and regulatory agencies) was carried out in parallel with an analysis of the technologies to identify important future environmental issues. Each of the final 20 issues selected by the project staff has the following common attributes: consensus of the environmental community that the issue is important; it is a likely candidate for future regulatory action; it deals with a major environmental aspect of energy development. The analyses of the 20 major issues address their environmental problem areas, current regulatory status, and the impact of future regulations. These analyses are followed by a quantitative assessment of the impact on energy costs and nationwide pollutant emissions of possible future regulations. This is accomplished by employing the Strategic Environmental Assessment System (SEAS) for a subset of the 20 major issues. The report concludes with a more general discussion of the impact of environmental regulatory action on energy development.

  12. Fetal and neonatal exposure to nicotine leads to augmented hepatic and circulating triglycerides in adult male offspring due to increased expression of fatty acid synthase

    SciTech Connect (OSTI)

    Ma, Noelle; Nicholson, Catherine J.; Wong, Michael; Holloway, Alison C.; Hardy, Daniel B.

    2014-02-15

    While nicotine replacement therapy is assumed to be a safer alternative to smoking during pregnancy, the long-term consequences for the offspring remain elusive. Animal studies now suggest that maternal nicotine exposure during perinatal life leads to a wide range of adverse outcomes for the offspring including increased adiposity. The focus of this study was to investigate if nicotine exposure during pregnancy and lactation leads to alterations in hepatic triglyceride synthesis. Female Wistar rats were randomly assigned to receive daily subcutaneous injections of saline (vehicle) or nicotine bitartrate (1 mg/kg/day) for two weeks prior to mating until weaning. At postnatal day 180 (PND 180), nicotine exposed offspring exhibited significantly elevated levels of circulating and hepatic triglycerides in the male offspring. This was concomitant with increased expression of fatty acid synthase (FAS), the critical hepatic enzyme in de novo triglyceride synthesis. Given that FAS is regulated by the nuclear receptor Liver X receptor (LXR?), we measured LXR? expression in both control and nicotine-exposed offspring. Nicotine exposure during pregnancy and lactation led to an increase in hepatic LXR? protein expression and enriched binding to the putative LXRE element on the FAS promoter in PND 180 male offspring. This was also associated with significantly enhanced acetylation of histone H3 [K9,14] surrounding the FAS promoter, a hallmark of chromatin activation. Collectively, these findings suggest that nicotine exposure during pregnancy and lactation leads to an increase in circulating and hepatic triglycerides long-term via changes in the transcriptional and epigenetic regulation of the hepatic lipogenic pathway. - Highlights: Our data reveals the links nicotine exposure in utero and long-term hypertriglyceridemia. It is due to nicotine-induced augmented expression of hepatic FAS and LXR? activity. Moreover, this involves nicotine-induced enhanced acetylation of

  13. Acid sphingomyelinase (aSMase) deficiency leads to abnormal microglia behavior and disturbed retinal function

    SciTech Connect (OSTI)

    Dannhausen, Katharina; Karlstetter, Marcus; Caramoy, Albert; Volz, Cornelia; Jägle, Herbert; Liebisch, Gerhard; Utermöhlen, Olaf; Langmann, Thomas

    2015-08-21

    Mutations in the acid sphingomyelinase (aSMase) coding gene sphingomyelin phosphodiesterase 1 (SMPD1) cause Niemann-Pick disease (NPD) type A and B. Sphingomyelin storage in cells of the mononuclear phagocyte system cause hepatosplenomegaly and severe neurodegeneration in the brain of NPD patients. However, the effects of aSMase deficiency on retinal structure and microglial behavior have not been addressed in detail yet. Here, we demonstrate that retinas of aSMase{sup −/−} mice did not display overt neuronal degeneration but showed significantly reduced scotopic and photopic responses in electroretinography. In vivo fundus imaging of aSMase{sup −/−} mice showed many hyperreflective spots and staining for the retinal microglia marker Iba1 revealed massive proliferation of retinal microglia that had significantly enlarged somata. Nile red staining detected prominent phospholipid inclusions in microglia and lipid analysis showed significantly increased sphingomyelin levels in retinas of aSMase{sup −/−} mice. In conclusion, the aSMase-deficient mouse is the first example in which microglial lipid inclusions are directly related to a loss of retinal function. - Highlights: • aSMase-deficient mice show impaired retinal function and reactive microgliosis. • aSMase-deficient microglia express pro-inflammatory transcripts. • aSMase-deficient microglia proliferate and have increased cell body size. • In vivo imaging shows hyperreflective spots in the fundus of aSMase-deficient mice. • aSMase-deficient microglia accumulate sphingolipid-rich intracellular deposits.

  14. Crystal Structures of the Reduced, Sulfenic Acid, and Mixed Disulfide Forms of SarZ, a Redox Active Global Regulator in Staphylococcus aureus

    SciTech Connect (OSTI)

    Poor, Catherine B.; Chen, Peng R.; Duguid, Erica; Rice, Phoebe A.; He, Chuan

    2010-01-20

    SarZ is a global transcriptional regulator that uses a single cysteine residue, Cys{sup 13}, to sense peroxide stress and control metabolic switching and virulence in Staphylococcus aureus. SarZ belongs to the single-cysteine class of OhrR-MgrA proteins that play key roles in oxidative resistance and virulence regulation in various bacteria. We present the crystal structures of the reduced form, sulfenic acid form, and mixed disulfide form of SarZ. Both the sulfenic acid and mixed disulfide forms are structurally characterized for the first time for this class of proteins. The Cys{sup 13} sulfenic acid modification is stabilized through two hydrogen bonds with surrounding residues, and the overall DNA-binding conformation is retained. A further reaction of the Cys{sup 13} sulfenic acid with an external thiol leads to formation of a mixed disulfide bond, which results in an allosteric change in the DNA-binding domains, disrupting DNA binding. Thus, the crystal structures of SarZ in three different states provide molecular level pictures delineating the mechanism by which this class of redox active regulators undergoes activation. These structures help to understand redox-mediated virulence regulation in S. aureus and activation of the MarR family proteins in general.

  15. Bidirectional CLOCK/BMAL1-dependent circadian gene regulation by retinoic acid in vitro

    SciTech Connect (OSTI)

    Shirai, Hidenori; Oishi, Katsutaka; Ishida, Norio . E-mail: n.ishida@aist.go.jp

    2006-12-15

    A central circadian clock located in the suprachiasmatic nucleus (SCN) of the mammalian hypothalamus entrains peripheral clocks through both neural and humoral factors. Although candidates for entrainment factors have been described, their details remain obscure. Here, we screened ligands for nuclear receptors that affect CLOCK/BMAL1-dependent transactivation of the mouse Period1 (mPer1) gene in NIH3T3 cells. We found that retinoic acids (RAs) significantly up-regulate mPer1 expression in an E-box-dependent manner. We also found that RAs up-regulate the expression of other E-box-dependent circadian genes such as mPer2, arginine vasopressin (mAVP), and peroxisome proliferator-activated receptor {alpha} (mPPAR{alpha}). Surprisingly, the effect of RAs on CLOCK/BMAL1 (E-box)-dependent mRNA expression was bidirectional and depended on the presence of exogenous retinoic acid receptor {alpha} (RAR{alpha}). These results suggest that RAs regulate the CLOCK/BMAL1-dependent transcription of circadian genes in a complex manner.

  16. Research, development, and demonstration of lead-acid batteries for electric-vehicle propulsion. Annual report, 1980

    SciTech Connect (OSTI)

    Not Available

    1981-03-01

    The first development effort in improving lead-acid batteries fore electric vehicles was the improvement of electric vehicle batteries using flat pasted positive plates and the second was for a tubular long life positive plate. The investigation of 32 component variables based on a flat pasted positive plate configuration is described. The experiment tested 96 - six volt batteries for characterization at 0, 25, and 40/sup 0/C and for cycle life capability at the 3 hour discharge rate with a one cycle, to 80% DOD, per day regime. Four positive paste formulations were selected. Two commercially available microporous separators were used in conjunction with a layer of 0.076 mm thick glass mat. Two concentrations of battery grade sulfuric acid were included in the test to determine if an increase in concentration would improve the battery capacity sufficient to offset the added weight of the more concentrated solution. Two construction variations, 23 plate elements with outside negative plates and 23 plate elements with outside positive plates, were included. The second development effort was an experiment designed to study the relationship of 32 component variables based on a tubular positive plate configuration. 96-six volt batteries were tested at various discharge rates at 0, 25, and 40/sup 0/C along with cycle life testing at 80% DOD of the 3 hour rate. 75 batteries remain on cycle life testing with 17 batteries having in excess of 365 life cycles. Preliminary conclusions indicate: the tubular positive plate is far more capable of withstanding deep cycles than is the flat pasted plate; as presently designed 40 Whr/kg can not be achieved, since 37.7 Whr/kg was the best tubular data obtained; electrolyte circulation is impaired due to the tight element fit in the container; and a redesign is required to reduce the battery weight which will improve the Whr/kg value. This redesign is complete and new molds have been ordered.

  17. Down-regulation of the Caffeic acid O-methyltransferase Gene in Switchgrass Reveals a Novel Monolignol Analog

    SciTech Connect (OSTI)

    Tschaplinski, Timothy J; Standaert, Robert F; Engle, Nancy L; Martin, Madhavi Z; Sangha, Amandeep K; Parks, Jerry M; Smith, Jeremy C; Samuel, Reichel; Pu, Yunqiao; Ragauskas, A J; Hamilton, Choo Yieng; Fu, Chunxiang; Wang, Zeng-Yu; Davison, Brian H; Dixon, Richard A; Mielenz, Jonathan R

    2012-01-01

    Down-regulation of the caffeic acid 3-O-methyltransferase (COMT) gene in the lignin biosynthetic pathway of switchgrass (Panicum virgatum) resulted in cell walls of transgenic plants releasing more constituent sugars after pretreatment by dilute acid and treatment with glycosyl hydrolases from an added enzyme preparation and from Clostridium thermocellum. Fermentation of both wild-type and transgenic switchgrass after milder hot water pretreatment with no water washing showed that only the transgenic switchgrass inhibited C. thermocellum. Gas chromatography-mass spectrometry-based metabolomics were undertaken on cell wall aqueous extracts to determine the nature of the microbial inhibitors, confirming the increased concentration of a number of phenolic acids and aldehydes that are known inhibitors of fermentation. Metabolomic analyses of the transgenic biomass additionally revealed the presence of a novel monolignol-like metabolite, identified as trans-3, 4-dimethoxy-5-hydroxycinnamyl alcohol (iso-sinapyl alcohol) in both non-pretreated, as well as hot water pretreated samples. Although there was no indication that iso-sinapyl alcohol was integrated into the cell wall, diversion of substrates from sinapyl alcohol to free iso-sinapyl alcohol, its glucoside, and associated upstream lignin pathway changes, including increased phenolic aldehydes and acids, are associated with more facile cell wall deconstruction, and to the observed inhibitory effect on microbial growth.

  18. LEADING WITH LEADING INDICATORS

    SciTech Connect (OSTI)

    PREVETTE, S.S.

    2005-01-27

    This paper documents Fluor Hanford's use of Leading Indicators, management leadership, and statistical methodology in order to improve safe performance of work. By applying these methods, Fluor Hanford achieved a significant reduction in injury rates in 2003 and 2004, and the improvement continues today. The integration of data, leadership, and teamwork pays off with improved safety performance and credibility with the customer. The use of Statistical Process Control, Pareto Charts, and Systems Thinking and their effect on management decisions and employee involvement are discussed. Included are practical examples of choosing leading indicators. A statistically based color coded dashboard presentation system methodology is provided. These tools, management theories and methods, coupled with involved leadership and employee efforts, directly led to significant improvements in worker safety and health, and environmental protection and restoration at one of the nation's largest nuclear cleanup sites.

  19. Down-regulation of gibberellic acid in poplar has negligible effects on host-plant suitability and insect pest response

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Buhl, Christine; Strauss, Steven H.; Lindroth, Richard L.

    2015-01-06

    Abstract Endogenous levels and signaling of gibberellin plant hormones such as gibberellic acid (GA) have been genetically down-regulated to create semi-dwarf varieties of poplar. The potential benefits of semi-dwarf stature include reduced risk of wind damage, improved stress tolerance, and improved wood quality. Despite these benefits, modification of growth traits may have consequences for non-target traits that confer defense against insect herbivores. According to the growth-differentiation balance hypothesis, reductions in growth may shift allocation of carbon from growth to chemical resistance traits, thereby altering plant defense. To date, host-plant suitability and pest response have not been comprehensively evaluated in GAmore » down-regulated plants. We quantified chemical resistance and nitrogen (an index of protein) in GA down-regulated and wild-type poplar (Populus alba × P. tremula) genotypes. We also evaluated performance of both generalist (Lymantria dispar) and specialist (Chrysomela scripta) insect pests reared on these genotypes. Our evaluation of resistance traits in four GA down-regulated genotypes revealed increased phenolic glycosides in one modified genotype and reduced lignin in two modified genotypes relative to the non-transgenic wild type. Nitrogen levels did not vary significantly among the experimental genotypes. Generalists reared on the four GA down-regulated genotypes exhibited reduced performance on only one modified genotype relative to the wild type. Specialists, however, performed similarly across all genotypes. Results from this study indicate that although some non-target traits varied among GA down-regulated genotypes, the differences in poplar pest susceptibility were modest and highly genotype-specific.« less

  20. Down-regulation of gibberellic acid in poplar has negligible effects on host-plant suitability and insect pest response

    SciTech Connect (OSTI)

    Buhl, Christine; Strauss, Steven H.; Lindroth, Richard L.

    2015-01-06

    Abstract Endogenous levels and signaling of gibberellin plant hormones such as gibberellic acid (GA) have been genetically down-regulated to create semi-dwarf varieties of poplar. The potential benefits of semi-dwarf stature include reduced risk of wind damage, improved stress tolerance, and improved wood quality. Despite these benefits, modification of growth traits may have consequences for non-target traits that confer defense against insect herbivores. According to the growth-differentiation balance hypothesis, reductions in growth may shift allocation of carbon from growth to chemical resistance traits, thereby altering plant defense. To date, host-plant suitability and pest response have not been comprehensively evaluated in GA down-regulated plants. We quantified chemical resistance and nitrogen (an index of protein) in GA down-regulated and wild-type poplar (Populus alba × P. tremula) genotypes. We also evaluated performance of both generalist (Lymantria dispar) and specialist (Chrysomela scripta) insect pests reared on these genotypes. Our evaluation of resistance traits in four GA down-regulated genotypes revealed increased phenolic glycosides in one modified genotype and reduced lignin in two modified genotypes relative to the non-transgenic wild type. Nitrogen levels did not vary significantly among the experimental genotypes. Generalists reared on the four GA down-regulated genotypes exhibited reduced performance on only one modified genotype relative to the wild type. Specialists, however, performed similarly across all genotypes. Results from this study indicate that although some non-target traits varied among GA down-regulated genotypes, the differences in poplar pest susceptibility were modest and highly genotype-specific.

  1. One carbon metabolism in anaerobic bacteria: Regulation of carbon and electron flow during organic acid production

    SciTech Connect (OSTI)

    Zeikus, J.G.; Jain, M.K.

    1992-01-01

    This reporting period, progress is reported on the following: metabolic pathway of solvent production in B. methylotrophicum; the biochemical mechanism for metabolic regulation of the succinate fermentation; models to understand the physiobiochemical function of formate metabolism in anaerobes and; models for understanding the influence of low pH on one carbon metabolism. (CBS)

  2. The Small Ethylene Response Factor ERF96 is Involved in the Regulation of the Abscisic Acid Response in Arabidopsis

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Wang, Xiaoping; Liu, Shanda; Tian, Hainan; Wang, Shucai; Chen, Jin-Gui

    2015-11-26

    Ethylene regulates many aspects of plant growth and development including seed germination, leaf senescence, and fruit ripening, and of plant responses to environmental stimuli including both biotic and abiotic stresses. Ethylene response factors (ERFs) are plant-specific transcription factors and are a subfamily of the AP2 (APETALA2)/ERF transcription factor family. The function of many members in this large gene family remains largely unknown. ERF96, a member of the Group IX ERF family transcription factors, has recently been shown to be a transcriptional activator that is involved in plant defense response in Arabidopsis. In this article, we provide evidence that ERF96 ismore » a positive regulator of abscisic acid (ABA) responses. Bioinformatics analysis indicated that there are a total four small ERFs in Arabidopsis including ERF95, ERF96, ERF97, and ERF98, and that ERF96 forms a cluster with ERF95 and ERF97. By using quantitative RT-PCR, we found that ERF96 is expressed in all tissues and organs examined except roots, with relatively high expression in flowers and seeds. Results from the protoplast transfection assay indicated that the EDLL motif-containing C-terminal domain is responsible for ERF96’s transcriptional activity. Although loss-of-function mutant of ERF96 was morphologically similar to wild type plants, transgenic plants overexpressing ERF96 had smaller rosette size and were delayed in flowering time. In ABA sensitivity assays, we found that ERF96 overexpression plants were hypersensitive to ABA in terms of ABA inhibition of seed germination, early seedling development and root elongation. Consistent with these observations, elevated transcript levels of some ABA-responsive genes including RD29A, ABI5, ABF3, ABF4, P5CS, and COR15A were observed in the transgenic plants in the presence of ABA. However, in the absence of ABA treatment, the transcript levels of these ABA-responsive genes remained largely unchanged. Our experiments also showed

  3. The Small Ethylene Response Factor ERF96 is Involved in the Regulation of the Abscisic Acid Response in Arabidopsis

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Wang, Xiaoping; Liu, Shanda; Tian, Hainan; Wang, Shucai; Chen, Jin-Gui

    2015-11-26

    We report that ethylene regulates many aspects of plant growth and development including seed germination, leaf senescence, and fruit ripening, and of plant responses to environmental stimuli including both biotic and abiotic stresses. Ethylene response factors (ERFs) are plant-specific transcription factors and are a subfamily of the AP2 (APETALA2)/ERF transcription factor family. The function of many members in this large gene family remains largely unknown. ERF96, a member of the Group IX ERF family transcription factors, has recently been shown to be a transcriptional activator that is involved in plant defense response in Arabidopsis. Here we provide evidence that ERF96more » is a positive regulator of abscisic acid (ABA) responses. Bioinformatics analysis indicated that there are a total four small ERFs in Arabidopsis including ERF95, ERF96, ERF97, and ERF98, and that ERF96 forms a cluster with ERF95 and ERF97. By using quantitative RT-PCR, we found that ERF96 is expressed in all tissues and organs examined except roots, with relatively high expression in flowers and seeds. Results from the protoplast transfection assay indicated that the EDLL motif-containing C-terminal domain is responsible for ERF96’s transcriptional activity. Although loss-of-function mutant of ERF96 was morphologically similar to wild type plants, transgenic plants overexpressing ERF96 had smaller rosette size and were delayed in flowering time. In ABA sensitivity assays, we found that ERF96 overexpression plants were hypersensitive to ABA in terms of ABA inhibition of seed germination, early seedling development and root elongation. Consistent with these observations, elevated transcript levels of some ABA-responsive genes including RD29A, ABI5, ABF3, ABF4, P5CS, and COR15A were observed in the transgenic plants in the presence of ABA. However, in the absence of ABA treatment, the transcript levels of these ABA-responsive genes remained largely unchanged. Our experiments also showed

  4. The Small Ethylene Response Factor ERF96 is Involved in the Regulation of the Abscisic Acid Response in Arabidopsis

    SciTech Connect (OSTI)

    Wang, Xiaoping; Liu, Shanda; Tian, Hainan; Wang, Shucai; Chen, Jin-Gui

    2015-11-26

    We report that ethylene regulates many aspects of plant growth and development including seed germination, leaf senescence, and fruit ripening, and of plant responses to environmental stimuli including both biotic and abiotic stresses. Ethylene response factors (ERFs) are plant-specific transcription factors and are a subfamily of the AP2 (APETALA2)/ERF transcription factor family. The function of many members in this large gene family remains largely unknown. ERF96, a member of the Group IX ERF family transcription factors, has recently been shown to be a transcriptional activator that is involved in plant defense response in Arabidopsis. Here we provide evidence that ERF96 is a positive regulator of abscisic acid (ABA) responses. Bioinformatics analysis indicated that there are a total four small ERFs in Arabidopsis including ERF95, ERF96, ERF97, and ERF98, and that ERF96 forms a cluster with ERF95 and ERF97. By using quantitative RT-PCR, we found that ERF96 is expressed in all tissues and organs examined except roots, with relatively high expression in flowers and seeds. Results from the protoplast transfection assay indicated that the EDLL motif-containing C-terminal domain is responsible for ERF96’s transcriptional activity. Although loss-of-function mutant of ERF96 was morphologically similar to wild type plants, transgenic plants overexpressing ERF96 had smaller rosette size and were delayed in flowering time. In ABA sensitivity assays, we found that ERF96 overexpression plants were hypersensitive to ABA in terms of ABA inhibition of seed germination, early seedling development and root elongation. Consistent with these observations, elevated transcript levels of some ABA-responsive genes including RD29A, ABI5, ABF3, ABF4, P5CS, and COR15A were observed in the transgenic plants in the presence of ABA. However, in the absence of ABA treatment, the transcript levels of these ABA-responsive genes remained largely unchanged. Our experiments also showed that

  5. Alisol B 23-acetate protects against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes involved in bile acid homeostasis

    SciTech Connect (OSTI)

    Meng, Qiang; Chen, Xin-li; Wang, Chang-yuan; Liu, Qi; Sun, Hui-jun; Sun, Peng-yuan; Huo, Xiao-kui; Liu, Zhi-hao; Yao, Ji-hong; Liu, Ke-xin

    2015-03-15

    Intrahepatic cholestasis is a clinical syndrome with systemic and intrahepatic accumulation of excessive toxic bile acids that ultimately cause hepatobiliary injury. Appropriate regulation of bile acids in hepatocytes is critically important for protection against liver injury. In the present study, we characterized the protective effect of alisol B 23-acetate (AB23A), a natural triterpenoid, on alpha-naphthylisothiocyanate (ANIT)-induced liver injury and intrahepatic cholestasis in mice and further elucidated the mechanisms in vivo and in vitro. AB23A treatment dose-dependently protected against liver injury induced by ANIT through reducing hepatic uptake and increasing efflux of bile acid via down-regulation of hepatic uptake transporters (Ntcp) and up-regulation of efflux transporter (Bsep, Mrp2 and Mdr2) expression. Furthermore, AB23A reduced bile acid synthesis through repressing Cyp7a1 and Cyp8b1, increased bile acid conjugation through inducing Bal, Baat and bile acid metabolism through an induction in gene expression of Sult2a1. We further demonstrate the involvement of farnesoid X receptor (FXR) in the hepatoprotective effect of AB23A. The changes in transporters and enzymes, as well as ameliorative liver histology in AB23A-treated mice were abrogated by FXR antagonist guggulsterone in vivo. In vitro evidences also directly demonstrated the effect of AB23A on FXR activation in a dose-dependent manner using luciferase reporter assay in HepG2 cells. In conclusion, AB23A produces protective effect against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes. - Highlights: • AB23A has at least three roles in protection against ANIT-induced liver injury. • AB23A decreases Ntcp, and increases Bsep, Mrp2 and Mdr2 expression. • AB23A represses Cyp7a1 and Cyp8b1 through inducing Shp and Fgf15 expression. • AB23A increases bile acid metabolism through inducing Sult2a1 expression. • FXR activation is involved

  6. Effects of setting regulators on the efficiency of an inorganic acid based alkali-free accelerator reacting with a Portland cement

    SciTech Connect (OSTI)

    Maltese, C. . E-mail: Building.lab@mapei.it; Pistolesi, C.; Bravo, A.; Cella, F.; Cerulli, T.; Salvioni, D.

    2007-04-15

    Today, in the field of underground constructions, alkali-free accelerators are commonly employed, during tunnel excavation, to allow flash concrete setting. In this way, the cementitious sprayed material can firmly bond to the tunnel walls, controlling the convergence (the tendency of the section to squeeze). Their efficiency may be related to many parameters like: cement type, setting regulator, concrete composition, working temperature. Nevertheless, the influence of such factors on the accelerator performance has not been clarified yet. The accelerator efficacy is evaluated by real spraying test in job site or, when only laboratory equipment are available, by measuring the final setting times of cement systems admixed with the accelerator. Several alkali-free flash setting admixtures are available on the market. They can be divided into two main categories both containing aluminium sulphate complexes stabilized either by inorganic acids or by organic acids. In this paper, the influence of different setting regulators on the performances of an inorganic acid based alkali-free accelerator was analysed. Portland cement samples were obtained by mixing clinker with gypsum, {alpha}-hemihydrate, {beta}-hemihydrate or anhydrite. The setting regulator instantaneous dissolution rates were evaluated through conductivity measurements. The setting time of cement pastes with and without the accelerator was measured. It was found that the shorter the final setting time (therefore the more efficient is the accelerator) the lower the setting regulator instantaneous dissolution rate. In order to understand this phenomenon, a comparison was performed between accelerated cement paste samples containing the setting regulator with the highest ({beta}-hemihydrate) and the lowest instantaneous dissolution rate (anhydrite). The analytical work included morphological (Environmental Scanning Electron Microscopy-Field Emission Gun - ESEM-FEG), crystal-chemical (X-Ray Powder Diffraction

  7. Standard operating procedure for the laboratory analysis of lead in paint, bulk dust, and soil by ultrasonic, acid digestion and inductively coupled plasma emission spectrometric measurement

    SciTech Connect (OSTI)

    Grohse, P.M.; Gutknecht, W.F.; Luk, K.K.; Wilson, B.M.; Van Hise, C.C.

    1997-09-01

    The details and performance of a simplified extraction procedure and analysis for three media are provided. Paint, bulk dust, and soil are collected using standard or referenced methods. Up to 0.25 g of paint, bulk dust, or soil weighted out and placed in a 50-mL centrifuge tube. Five mL of 25% (v/v) nitric acid is added and the sample is ultrasonicated for 30 minutes.

  8. Accumulated SET protein up-regulates and interacts with hnRNPK, increasing its binding to nucleic acids, the Bcl-xS repression, and cellular proliferation

    SciTech Connect (OSTI)

    Almeida, Luciana O.; Garcia, Cristiana B.; Matos-Silva, Flavia A.; Curti, Carlos; Leopoldino, Andria M.

    2014-02-28

    Highlights: hnRNPK is a new target of SET. SET regulates hnRNPK. SET and hnRNPK accumulation promotes tumorigenesis. SET accumulation is a potential model to study genes regulated by SET-hnRNPK. - Abstract: SET and hnRNPK are proteins involved in gene expression and regulation of cellular signaling. We previously demonstrated that SET accumulates in head and neck squamous cell carcinoma (HNSCC); hnRNPK is a prognostic marker in cancer. Here, we postulate that SET and hnRNPK proteins interact to promote tumorigenesis. We performed studies in HEK293 and HNSCC (HN6, HN12, and HN13) cell lines with SET/hnRNPK overexpression and knockdown, respectively. We found that SET and/or hnRNPK protein accumulation increased cellular proliferation. SET accumulation up-regulated hnRNPK mRNA and total/phosphorylated protein, promoted hnRNPK nuclear location, and reduced Bcl-x mRNA levels. SET protein directly interacted with hnRNPK, increasing both its binding to nucleic acids and Bcl-xS repression. We propose that hnRNPK should be a new target of SET and that SEThnRNPK interaction, in turn, has potential implications in cell survival and malignant transformation.

  9. Dissolution of lead paint in aqueous solutions

    SciTech Connect (OSTI)

    Barnes, G.L.; Davis, A.P.

    1996-07-01

    An analysis of the rate and extent of lead leaching from a lead-based paint was completed. At low-solution pH, dissolution was rapid and approached 80% of the total lead. Residual lead can be estimated based on the predicted solubility of lead carbonate and basic lead carbonate. Release of lead from the paint was slower than that from pure basic lead carbonate due to inhibition by the paint matrix. Although the dissolved concentration of lead in solution at neutral/high pH was low, the paint binder was apparently destroyed at these pH values, releasing colloidal lead pigment particles. The presence of ethylenediaminetetraacetic acid (EDTA) and nitrilotriacetic acid (NTA) enhanced both the rate and degree of lead dissolution, while benzoic acid had a minimal effect.

  10. What is lead-based paint

    SciTech Connect (OSTI)

    Vernon, L.S.

    1994-03-01

    The number of variety of lead-abatement regulations and requirements make it difficult and confusing to identify and properly respond to dangerous levels of lead in every situation. Definitions of lead-based paint'' and three test methods for lead detection are described to help determine when and how to test for the presence of lead.

  11. Regulation of gene expression and subcellular protein distribution in MLO-Y4 osteocytic cells by lysophosphatidic acid: Relevance to dendrite outgrowth.

    SciTech Connect (OSTI)

    Waters, Katrina M.; Jacobs, Jon M.; Gritsenko, Marina A.; Karin, Norman J.

    2011-02-26

    Osteoblastic and osteocytic cells are highly responsive to the lipid growth factor lysophosphatidic acid (LPA) but the mechanisms by which LPA alters bone cell functions are largely unknown. A major effect of LPA on osteocytic cells is the stimulation of dendrite membrane outgrowth, a process that we predicted to require changes in gene expression and protein distribution. We employed DNA microarrays for global transcriptional profiling of MLO-Y4 osteocytic cells grown for 6 and 24h in the presence or absence of LPA. We identified 932 transcripts that displayed statistically significant changes in abundance of at least 1.25-fold in response to LPA treatment. Gene ontology (GO) analysis revealed that the regulated gene products were linked to diverse cellular processes, including DNA repair, response to unfolded protein, ossification, protein-RNA complex assembly, and amine biosynthesis. Gene products associated with the regulation of actin microfilament dynamics displayed the most robust expression changes, and LPA-induced dendritogenesis in vitro was blocked by the stress fiber inhibitor cytochalasin D. Mass spectrometry-based proteomic analysis of MLO-Y4 cells revealed significant LPA-induced changes in the abundance of 284 proteins at 6h and 844 proteins at 24h. GO analysis of the proteomic data linked the effects of LPA to cell processes that control of protein distribution and membrane outgrowth, including protein localization, protein complex assembly, Golgi vesicle transport, cytoskeleton-dependent transport, and membrane invagination/endocytosis. Dendrites were isolated from LPA-treated MLO-Y4 cells and subjected to proteomic analysis to quantitatively assess the subcellular distribution of proteins. Sets of 129 and 36 proteins were enriched in the dendrite fraction as compared to whole cells after 6h and 24h of LPA exposure, respectively. Protein markers indicated that membranous organelles were largely excluded from the dendrites. Highly represented among

  12. Industrial lead paint removal specifications

    SciTech Connect (OSTI)

    Stone, R.C.

    1997-06-01

    The purpose of this paper is to inform the reader as to some of the pertinent rules and regulations promulgated by the Environmental Protection Agency (EPA) and the Occupational Safety and Health Administration (OSHA) that may effect an industrial lead paint removal project. The paper discusses a recommended schedule of procedures and preparations to be followed by the lead paint removal specification writer when analyzing the possible impact of the project on the environment, the public and workers. Implications of the Clean Air Act, the Clean Water Act and the Resource Conservation and Recovery Act (RCRA) along with hazardous waste handling, manifesting, transporting and disposal procedures are discussed with special emphasis placed as to their impact on the writer and the facility owner. As the rules and regulations are highly complex, the writer has attempted to explain the methodology currently being used in state-of-the-art industrial lead abatement specifications.

  13. Soluble Lead Flow Battery: Soluble Lead Flow Battery Technology

    SciTech Connect (OSTI)

    2010-09-01

    GRIDS Project: General Atomics is developing a flow battery technology based on chemistry similar to that used in the traditional lead-acid battery found in nearly every car on the road today. Flow batteries store energy in chemicals that are held in tanks outside the battery. When the energy is needed, the chemicals are pumped through the battery. Using the same basic chemistry as a traditional battery but storing its energy outside of the cell allows for the use of very low cost materials. The goal is to develop a system that is far more durable than today’s lead-acid batteries, can be scaled to deliver megawatts of power, and which lowers the cost of energy storage below $100 per kilowatt hour.

  14. Acid mine drainage: Balancing environmental protection and mining realities

    SciTech Connect (OSTI)

    Sturgill, B.J. Jr.; Poland, K.B.

    1995-12-31

    A major environmental concern leading to the enactment of the Surface Mining Control and Reclamation Act of 1977 (SMCRA) was the degradation of streams and waterways from discharges of acid mine drainage (AMD) resulting from coal mining operations. Although SMCRA and its regulatory scheme contains specific provisions addressing the drainage of acidic water from mine sites, as do various other agencies statutes and regulations, AMD from active and abandoned mines remains a major environmental problem in the Appalachian region. The formation of acidic water during coal mining operations is pervasive and some believe impossible to prevent.

  15. Getting the Lead Out

    DOE R&D Accomplishments [OSTI]

    Gibson, Kerry

    2011-04-08

    Discarded electronics no longer pose an environmental hazard from lead solder thanks to a lead-free alternative developed at the Ames Laboratory.

  16. Identification of a classical mutant in the industrial host Aspergillus niger by systems genetics: LaeA is required for citric acid production and regulates the formation of some secondary metabolites

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Niu, Jing; Arentshorst, Mark; Nair, P. Deepa S.; Dai, Ziyu; Baker, Scott E.; Frisvad, Jens C.; Nielsen, Kristian F.; Punt, Peter J.; Ram, Arthur F. J.

    2015-11-13

    The asexual filamentous fungus Aspergillus niger is an important industrial cell factory for citric acid production. In this study, we genetically characterized a UV-generated A. niger mutant that was originally isolated as a nonacidifying mutant, which is a desirable trait for industrial enzyme production. Physiological analysis showed that this mutant did not secrete large amounts of citric acid and oxalic acid, thus explaining the nonacidifying phenotype. As traditional complementation approaches to characterize the mutant genotype were unsuccessful, we used bulk segregant analysis in combination with high-throughput genome sequencing to identify the mutation responsible for the nonacidifying phenotype. Since A. nigermore » has no sexual cycle, parasexual genetics was used to generate haploid segregants derived from diploids by loss of whole chromosomes. We found that the nonacidifying phenotype was caused by a point mutation in the laeA gene. LaeA encodes a putative methyltransferase-domain protein, which we show here to be required for citric acid production in an A. niger lab strain (N402) and in other citric acid production strains. The unexpected link between LaeA and citric acid production could provide new insights into the transcriptional control mechanisms related to citric acid production in A. niger. Interestingly, the secondary metabolite profile of a ΔlaeA strain differed from the wild-type strain, showing both decreased and increased metabolite levels, indicating that LaeA is also involved in regulating the production of secondary metabolites. As a result, we show that our systems genetics approach is a powerful tool to identify trait mutations.« less

  17. Identification of a classical mutant in the industrial host Aspergillus niger by systems genetics: LaeA is required for citric acid production and regulates the formation of some secondary metabolites

    SciTech Connect (OSTI)

    Niu, Jing; Arentshorst, Mark; Nair, P. Deepa S.; Dai, Ziyu; Baker, Scott E.; Frisvad, Jens C.; Nielsen, Kristian F.; Punt, Peter J.; Ram, Arthur F. J.

    2015-11-13

    The asexual filamentous fungus Aspergillus niger is an important industrial cell factory for citric acid production. In this study, we genetically characterized a UV-generated A. niger mutant that was originally isolated as a nonacidifying mutant, which is a desirable trait for industrial enzyme production. Physiological analysis showed that this mutant did not secrete large amounts of citric acid and oxalic acid, thus explaining the nonacidifying phenotype. As traditional complementation approaches to characterize the mutant genotype were unsuccessful, we used bulk segregant analysis in combination with high-throughput genome sequencing to identify the mutation responsible for the nonacidifying phenotype. Since A. niger has no sexual cycle, parasexual genetics was used to generate haploid segregants derived from diploids by loss of whole chromosomes. We found that the nonacidifying phenotype was caused by a point mutation in the laeA gene. LaeA encodes a putative methyltransferase-domain protein, which we show here to be required for citric acid production in an A. niger lab strain (N402) and in other citric acid production strains. The unexpected link between LaeA and citric acid production could provide new insights into the transcriptional control mechanisms related to citric acid production in A. niger. Interestingly, the secondary metabolite profile of a ΔlaeA strain differed from the wild-type strain, showing both decreased and increased metabolite levels, indicating that LaeA is also involved in regulating the production of secondary metabolites. As a result, we show that our systems genetics approach is a powerful tool to identify trait mutations.

  18. Functional nucleic acid probes and uses thereof

    DOE Patents [OSTI]

    Nilsen-Hamilton, Marit

    2006-10-03

    The present invention provides functional nucleic acid probes, and methods of using functional nucleic acid probes, for binding a target to carry out a desired function. The probes have at least one functional nucleic acid, at least one regulating nucleic acid, and at least one attenuator. The functional nucleic acid is maintained in an inactive state by the attenuator and activated by the regulating nucleic acid only in the presence of a regulating nucleic acid target. In its activated state the functional nucleic acid can bind to its target to carry out a desired function, such as generating a signal, cleaving a nucleic acid, or catalyzing a reaction.

  19. RNA-guided transcriptional regulation

    DOE Patents [OSTI]

    Church, George M.; Mali, Prashant G.; Esvelt, Kevin M.

    2016-02-23

    Methods of modulating expression of a target nucleic acid in a cell are provided including introducing into the cell a first foreign nucleic acid encoding one or more RNAs complementary to DNA, wherein the DNA includes the target nucleic acid, introducing into the cell a second foreign nucleic acid encoding a nuclease-null Cas9 protein that binds to the DNA and is guided by the one or more RNAs, introducing into the cell a third foreign nucleic acid encoding a transcriptional regulator protein or domain, wherein the one or more RNAs, the nuclease-null Cas9 protein, and the transcriptional regulator protein or domain are expressed, wherein the one or more RNAs, the nuclease-null Cas9 protein and the transcriptional regulator protein or domain co-localize to the DNA and wherein the transcriptional regulator protein or domain regulates expression of the target nucleic acid.

  20. VOLUMETRIC LEAD ASSAY

    SciTech Connect (OSTI)

    M.A. Ebadian, Ph.D.; S.K. Dua; David Roelant; Sachin Kumar

    2001-01-01

    This report describes a system for handling and radioassay of lead, consisting of a robot, a conveyor, and a gamma spectrometer. The report also presents a cost-benefit analysis of options: radioassay and recycling lead vs. disposal as waste.

  1. Down-regulation of p-coumaroyl quinate/shikimate 3'-hydroxylase (C3'H) and cinnamate 4-hydroxylase (C4H) genes in the lignin biosynthetic pathway of Eucalyptus urophylla x E. grandis leads to improved sugar release

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Sykes, Robert W.; Gjersing, Erica L.; Foutz, Kirk; Rottmann, William H.; Kuhn, Sean A.; Foster, Cliff E.; Ziebell, Angela; Turner, Geoffrey B.; Decker, Stephen R.; Hinchee, Maud A. W.; et al

    2015-08-27

    In this study, lignocellulosic materials provide an attractive replacement for food-based crops used to produce ethanol. Understanding the interactions within the cell wall is vital to overcome the highly recalcitrant nature of biomass. One factor imparting plant cell wall recalcitrance is lignin, which can be manipulated by making changes in the lignin biosynthetic pathway. In this study, eucalyptus down-regulated in expression of cinnamate 4-hydroxylase (C4H, EC 1.14.13.11) or p-coumaroyl quinate/shikimate 3'-hydroxylase (C3'H, EC 1.14.13.36) were evaluated for cell wall composition and reduced recalcitrance.

  2. One carbon metabolism in anaerobic bacteria: Regulation of carbon and electron flow during organic acid production. Progress report, June 1990--May 1992

    SciTech Connect (OSTI)

    Zeikus, J.G.; Jain, M.K.

    1992-04-01

    This reporting period, progress is reported on the following: metabolic pathway of solvent production in B. methylotrophicum; the biochemical mechanism for metabolic regulation of the succinate fermentation; models to understand the physiobiochemical function of formate metabolism in anaerobes and; models for understanding the influence of low pH on one carbon metabolism. (CBS)

  3. Lead carbonate scintillator materials

    DOE Patents [OSTI]

    Derenzo, Stephen E.; Moses, William W.

    1991-01-01

    Improved radiation detectors containing lead carbonate or basic lead carbonate as the scintillator element are disclosed. Both of these scintillators have been found to provide a balance of good stopping power, high light yield and short decay constant that is superior to other known scintillator materials. The radiation detectors disclosed are favorably suited for use in general purpose detection and in medical uses.

  4. Managing lead-based paint abatement wastes

    SciTech Connect (OSTI)

    Steele, N.L.C.

    1994-12-31

    Renovation, remodeling, demolition, and surface preparation for painting, in addition to specified lead abatement, are all activities that have the potential to produce hazardous wastes if a property was painted with lead-based paint. Lead-based paint was used on residential structures until 1978, when most residential uses were banned by the Consumer Products Safety Council. Prior to the 1950s, paints for residential uses may have contained up to 50% lead by weight. Today, commercial and military paints may still contain lead and can be used on non-residential structures. The lead content of residential paints is limited to 0.06% lead (by weight) in the dried film. This paper provides an overview of some of the information needed to properly manage lead-based paint abatement wastes. The issues covered in this paper include waste classification, generator status, treatment, and land disposal restrictions. The author assumes that the reader is familiar with the provision of the Health and Safety Code and the California Code of Regulations that pertain to generation and management of hazardous wastes. Citations provided herein do not constitute an exhaustive list of all the regulations with which a generator of hazardous waste must comply.

  5. lead paint chart

    Office of Environmental Management (EM)

    1930 Assume Lead Will WX Disturb Paint? No Yes Will WX Disturb More than 2 ft 2 . per Room? Yes HUD Housing or Using HUD ? Yes More than 50ugm 3 ? No LSW & HUD Rule 35.900 **...

  6. Lead carbonate scintillator materials

    DOE Patents [OSTI]

    Derenzo, S.E.; Moses, W.W.

    1991-05-14

    Improved radiation detectors containing lead carbonate or basic lead carbonate as the scintillator element are disclosed. Both of these scintillators have been found to provide a balance of good stopping power, high light yield and short decay constant that is superior to other known scintillator materials. The radiation detectors disclosed are favorably suited for use in general purpose detection and in medical uses. 3 figures.

  7. Activation of PPAR{delta} up-regulates fatty acid oxidation and energy uncoupling genes of mitochondria and reduces palmitate-induced apoptosis in pancreatic {beta}-cells

    SciTech Connect (OSTI)

    Wan, Jun; Jiang, Li; Lue, Qingguo; Ke, Linqiu; Li, Xiaoyu; Tong, Nanwei

    2010-01-15

    Recent evidence indicates that decreased oxidative capacity, lipotoxicity, and mitochondrial aberrations contribute to the development of insulin resistance and type 2 diabetes. The goal of this study was to investigate the effects of peroxisome proliferator-activated receptor {delta} (PPAR{delta}) activation on lipid oxidation, mitochondrial function, and insulin secretion in pancreatic {beta}-cells. After HIT-T15 cells (a {beta}-cell line) were exposed to high concentrations of palmitate and GW501516 (GW; a selective agonist of PPAR{delta}), we found that administration of GW increased the expression of PPAR{delta} mRNA. GW-induced activation of PPAR{delta} up-regulated carnitine palmitoyltransferase 1 (CPT1), long-chain acyl-CoA dehydrogenase (LCAD), pyruvate dehydrogenase kinase 4 (PDK4), and uncoupling protein 2 (UCP2); alleviated mitochondrial swelling; attenuated apoptosis; and reduced basal insulin secretion induced by increased palmitate in HIT cells. These results suggest that activation of PPAR{delta} plays an important role in protecting pancreatic {beta}-cells against aberrations caused by lipotoxicity in metabolic syndrome and diabetes.

  8. LEAD SEVERING CONTRIVANCE

    DOE Patents [OSTI]

    Widmaier, W.

    1958-04-01

    A means for breaking an electrical circuit within an electronic tube during the process of manufacture is described. Frequently such circuits must be employed for gettering or vapor coating purposes, however, since an external pair of corector pins having no use after manufacture, is undesirable, this invention permits the use of existing leads to form a temporary circuit during manufacture, and severing it thereafter. One portion of the temporary circuit, made from a springy material such as tungsten, is spot welded to a fusable member. To cut the circuit an external radiant heat source melts the fusable member, allowing the tensed tungsten spring to contract and break the circuit. This inexpensive arrangement is particularly useful when the tube has a great many external leads crowded into the tube base.

  9. Acquisition Regulation

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Career Development, Contracting Authority and Responsibilities Acquisition Regulation ... file, except for any documents required by regulation to be maintained in paper copy. ...

  10. Evaluation of lead/carbon devices for utility applications : a study for the DOE Energy Storage Program.

    SciTech Connect (OSTI)

    Walmet, Paula S.

    2009-06-01

    This report describes the results of a three-phase project that evaluated lead-based energy storage technologies for utility-scale applications and developed carbon materials to improve the performance of lead-based energy storage technologies. In Phase I, lead/carbon asymmetric capacitors were compared to other technologies that used the same or similar materials. At the end of Phase I (in 2005) it was found that lead/carbon asymmetric capacitors were not yet fully developed and optimized (cost/performance) to be a viable option for utility-scale applications. It was, however, determined that adding carbon to the negative electrode of a standard lead-acid battery showed promise for performance improvements that could be beneficial for use in utility-scale applications. In Phase II various carbon types were developed and evaluated in lead-acid batteries. Overall it was found that mesoporous activated carbon at low loadings and graphite at high loadings gave the best cycle performance in shallow PSoC cycling. Phase III studied cost/performance benefits for a specific utility application (frequency regulation) and the full details of this analysis are included as an appendix to this report.

  11. Generating Energy Efficiency Project Leads and Allocating Leads to

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Contractors | Department of Energy Energy Efficiency Project Leads and Allocating Leads to Contractors Generating Energy Efficiency Project Leads and Allocating Leads to Contractors Better Buildings Residential Network Peer Exchange Call Series: Generating Energy Efficiency Project Leads and Allocating Leads to Contractors, Call Slides and Discussion Summary, February 26, 2015. Call Slides and Discussion Summary (2.1 MB) More Documents & Publications Unique Fee-for-Service Revenues Think

  12. Generating Energy Efficiency Project Leads and Allocating Leads...

    Energy Savers [EERE]

    Generating Energy Efficiency Project Leads and Allocating Leads to Contractors Better Buildings Residential Network Peer Exchange Call Series: Generating Energy Efficiency Project ...

  13. Regulations | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Information Center Regulations Regulations Personnel Security Regulations Click Here FOIA Regulations Click Here Privacy Act Regulations Click Here Whistleblower Protection ...

  14. WPN 08-6: Interim Lead-Safe Weatherization Guidance

    Broader source: Energy.gov [DOE]

    To provide additional guidance for an LSW component of a health and safety plan. This guidance builds on the foundation provided in WPN 02-6, Weatherization Activities and Federal Lead Based Paint Regulations.

  15. Home refinishing, lead paint, and infant blood lead levels

    SciTech Connect (OSTI)

    Rabinowitz, M.; Leviton, A.; Bellinger, D.

    1985-04-01

    The blood lead levels of 249 infants were measured semi-annually from birth to two years of age; the home paint was sampled and any recent home refinishing activity recorded. Mean blood lead from birth to age 2 years did not vary systematically with age but did correlate significantly with the amount of lead in the indoor paint. Refinishing activity in homes with high lead paint was associated with elevations of blood lead averaging 69 per cent.

  16. VOLTAGE REGULATOR

    DOE Patents [OSTI]

    Von Eschen, R.L.; Scheele, P.F.

    1962-04-24

    A transistorized voltage regulator which provides very close voitage regulation up to about 180 deg F is described. A diode in the positive line provides a constant voltage drop from the input to a regulating transistor emitter. An amplifier is coupled to the positive line through a resistor and is connected between a difference circuit and the regulating transistor base which is negative due to the difference in voltage drop across thc diode and the resistor so that a change in the regulator output causes the amplifier to increase or decrease the base voltage and current and incrcase or decrease the transistor impedance to return the regulator output to normal. (AEC)

  17. Breakthrough: Lead-free Solder

    ScienceCinema (OSTI)

    Anderson, Iver

    2013-03-01

    Ames Laboratory senior metallurgist Iver Anderson explains the importance of lead-free solder in taking hazardous lead out of the environment by eliminating it from discarded computers and electronics that wind up in landfills. Anderson led a team that developed a tin-silver-copper replacement for traditional lead-tin solder that has been adopted by more than 50 companies worldwide.

  18. Lead-based paint assessment

    SciTech Connect (OSTI)

    Lorie, C.; Cowdery, J.W.

    1994-12-31

    In 1977, The US consumer product safety commission banned the use of lead-based paint (LBP) in all industries, except the maritime industry which still has certain privileged uses. Unfortunately for property and building owners, the ban did not come soon enough. In response to this heightened awareness, several environmental market sectors addressing the issues have emerged. These include: residential; soil; commercial; water; and structures. The first and most important step in addressing the concerns posed by the existence of lead based contamination is to quantify the amount of lead-based product, to determine the location of the lead based product and the extent, if any, of lead based contamination, and to make recommendations for the remediation or abatement of the lead product and resultant contamination. In narrowing the focus of these issues, this paper discusses lead-based paint assessment; preparing and organizing the assessment, the regulatory considerations, assessment methodology, and presentation of results.

  19. One Vaccine Leads to Another

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Energy One Thing Leads to Another: How NETL Research Saves Lives One Thing Leads to Another: How NETL Research Saves Lives August 8, 2013 - 10:57am Addthis One Thing Leads to Another: How NETL Research Saves Lives Learn More The coronary stent was developed as part of NETL's Technology Transfer program. NETL's technology portfolio contains a broad range of innovations that have resulted from research in areas such as carbon capture and sequestration, mercury capture, fuel cells, sensors and

  20. One Vaccine Leads to Another

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    One Vaccine Leads to Another Print Diphtheria is a potentially lethal respiratory disease that is fairly well controlled by vaccines discovered early last century. These vaccines...

  1. High temperature superconductor current leads

    DOE Patents [OSTI]

    Hull, John R.; Poeppel, Roger B.

    1995-01-01

    An electrical lead having one end for connection to an apparatus in a cryogenic environment and the other end for connection to an apparatus outside the cryogenic environment. The electrical lead includes a high temperature superconductor wire and an electrically conductive material distributed therein, where the conductive material is present at the one end of the lead at a concentration in the range of from 0 to about 3% by volume, and at the other end of the lead at a concentration of less than about 20% by volume. Various embodiments are shown for groups of high temperature superconductor wires and sheaths.

  2. High temperature superconductor current leads

    DOE Patents [OSTI]

    Hull, J.R.; Poeppel, R.B.

    1995-06-20

    An electrical lead is disclosed having one end for connection to an apparatus in a cryogenic environment and the other end for connection to an apparatus outside the cryogenic environment. The electrical lead includes a high temperature superconductor wire and an electrically conductive material distributed therein, where the conductive material is present at the one end of the lead at a concentration in the range of from 0 to about 3% by volume, and at the other end of the lead at a concentration of less than about 20% by volume. Various embodiments are shown for groups of high temperature superconductor wires and sheaths. 9 figs.

  3. Lead-free primary explosives

    DOE Patents [OSTI]

    Huynh, My Hang V.

    2010-06-22

    Lead-free primary explosives of the formula (cat).sub.Y[M.sup.II(T).sub.X(H.sub.2O).sub.6-X].sub.Z, where T is 5-nitrotetrazolate, and syntheses thereof are described. Substantially stoichiometric equivalents of the reactants lead to high yields of pure compositions thereby avoiding dangerous purification steps.

  4. Leads | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Leads Human Subjects Protection Program (HSPP) HSPP Home About For Researchers For IRB Managers / Administrators For IRB Members For Institutional Officials For Prospective Human Subjects Leads Annual Reports Institutional Review Boards (IRBs) Education and Resources Regulations and Requirements Glossary Abbreviations Contact BER Home Contact Information Human Subjects Protection Program U.S. Department of Energy SC-23/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 About

  5. NATIONAL LEAD COMPANY OF OHIO

    Office of Legacy Management (LM)

    8 Radiatlon Dept. 3 Water Treatment Plant (Far W&or Spnphs Only) NILHhS-1?6 (RFV lO... 8 Radiation Dept. 3 Water Treotmnt Plant (Fw Wkr bnplos Only) NATIONAL. LEAD ...

  6. One Vaccine Leads to Another

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    One Vaccine Leads to Another One Vaccine Leads to Another Print Friday, 24 May 2013 11:19 Diphtheria is a potentially lethal respiratory disease that is fairly well controlled by vaccines discovered early last century. These vaccines have been extremely effective; studies on one vaccine in particular, the nontoxic form of the diphtheria toxin (DT), have informed other vaccines. Recently, researchers at Novartis GNF solved several structures of a nontoxic DT using data obtained at ALS Beamline

  7. Crystal structure of Spot 14, a modulator of fatty acid synthesis

    SciTech Connect (OSTI)

    Colbert, Christopher L.; Kim, Chai-Wan; Moon, Young-Ah; Henry, Lisa; Palnitkar, Maya; McKean, William B.; Fitzgerald, Kevin; Deisenhofer, Johann; Horton, Jay D.; Kwon, Hyock Joo

    2011-09-06

    Spot 14 (S14) is a protein that is abundantly expressed in lipogenic tissues and is regulated in a manner similar to other enzymes involved in fatty acid synthesis. Deletion of S14 in mice decreased lipid synthesis in lactating mammary tissue, but the mechanism of S14's action is unknown. Here we present the crystal structure of S14 to 2.65 {angstrom} and biochemical data showing that S14 can form heterodimers with MIG12. MIG12 modulates fatty acid synthesis by inducing the polymerization and activity of acetyl-CoA carboxylase, the first committed enzymatic reaction in the fatty acid synthesis pathway. Coexpression of S14 and MIG12 leads to heterodimers and reduced acetyl-CoA carboxylase polymerization and activity. The structure of S14 suggests a mechanism whereby heterodimer formation with MIG12 attenuates the ability of MIG12 to activate ACC.

  8. Leading the Charge: Christine Klein

    Office of Energy Efficiency and Renewable Energy (EERE)

    Change doesn’t happen on its own. It’s led by dedicated and passionate people who are committed to empowering Indian Country to energize future generations. Leading the Charge is a regular Office of Indian Energy newsletter feature spotlighting the movers and shakers in energy development on tribal lands. In this issue, we talk to Christine Klein, an adopted Haida who is leading efforts to help Alaska Native villages address their energy challenges in her role as Vice President and Chief Operating Officer of the Calista Corporation.

  9. Acquisition Regulation

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    6 Rev. 1 Date 09/09/2015 Department of Energy No. FAL 2015-04 Rev. 1 Date 09/09/2015 Financial Assistance Regulations ACQUISITION/FINANCIAL ASSISTANCE LETTER This Acquisition/Financial Assistance Letter is issued under the authority of the Senior Procurement Executive of DOE. It is intended for use by procurement professionals of DOE, primarily Contracting Officers, and other officials of DOE that are involved in the acquisition process. Other parties are welcome to its information, but

  10. Batteries called primary source of lead, cadmium in municipal waste

    SciTech Connect (OSTI)

    Not Available

    1989-04-01

    The US Environmental Protection Agency reports that lead-acid batteries, such as those used in automobiles, and rechargeable nickel-cadmium batteries used in consumer electronics equipment, are the primary sources of lead and cadmium in municipal trash and garbage. A report prepared for EPA analyzed existing data from 1970 to 1986 and made projections to the year 2000. Lead-acid batteries continue to constitute a major source of lead in garbage even though 80 percent of them are now recycled. As a result, EPA is calling for additional recycling of batteries. This study is an important step in implementing EPA's strategy for helping states and cities achieve the national goal of recycling and reducing 25 percent of all municipal garbage by 1992. The findings on batteries are the result of a study conducted for EPA because of concern over the levels of lead and cadmium found n ash (residue) from municipal waste incinerators. Lead and cadmium are two metals of particular concern in the solid waste stream. The metals can contaminate soil and groundwater when landfilled. They also may be found in some incinerator emissions.

  11. NATIONAL LEAD COMPANY OF OHIO

    Office of Legacy Management (LM)

    t-t AL- 1. + T fi r,y* t ,.- . NATIONAL LEAD COMPANY OF OHIO Ofll i iy Ci)wp HEALTH AND SAFETY DIVISION - ANALYTICAL DEPT. ANALYTICAL DATA SHEET U-G b ;33y jl:tL G c-w &3(y I...

  12. One Vaccine Leads to Another

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    One Vaccine Leads to Another Print Diphtheria is a potentially lethal respiratory disease that is fairly well controlled by vaccines discovered early last century. These vaccines have been extremely effective; studies on one vaccine in particular, the nontoxic form of the diphtheria toxin (DT), have informed other vaccines. Recently, researchers at Novartis GNF solved several structures of a nontoxic DT using data obtained at ALS Beamline 5.0.3, resolving a long-standing scientific puzzle and

  13. NATIONAL LEAD COMPANY OF OHIO

    Office of Legacy Management (LM)

    ~y-f-hjLo-- yy; 4: j ).,Ic +- NATIONAL LEAD COMPANY OF OHIO s _ HEALTH AND SAFETY DIVISION - ANALYTICAL DEPT. . ANALYTICAL DATA SHEET o-0 1. H. NO. TRIAL, HYGIENE AND RADIATION DEPT. AMPLE Nti.1. //- 6:itEC TEDI it/;/L 5 .,- -..-- -- -.._-. -. I --- --- 1 ANALYTICA .OATE RECeiVEDi mri /-2-v& 3 Li >,a. HCJ _-..k.-*..- -.v._ 1 NO. DISTRIBUTION OF COPIES 1 Analytlcal Labwatwy (RECORD COPP) 2 Industrial Hygiene 8 Radlation Dept. . 3' Water Treatment Plant (Far Water Smmplos Only)' t' , /,' 30

  14. 10-oxo-12(Z)-octadecenoic acid, a linoleic acid metabolite produced by gut lactic acid bacteria, potently activates PPARγ and stimulates adipogenesis

    SciTech Connect (OSTI)

    Goto, Tsuyoshi; Kim, Young-Il; Furuzono, Tomoya; Takahashi, Nobuyuki; Yamakuni, Kanae; Yang, Ha-Eun; Li, Yongjia; Ohue, Ryuji; Nomura, Wataru; Sugawara, Tatsuya; Yu, Rina; Kitamura, Nahoko; and others

    2015-04-17

    Our previous study has shown that gut lactic acid bacteria generate various kinds of fatty acids from polyunsaturated fatty acids such as linoleic acid (LA). In this study, we investigated the effects of LA and LA-derived fatty acids on the activation of peroxisome proliferator-activated receptors (PPARs) which regulate whole-body energy metabolism. None of the fatty acids activated PPARδ, whereas almost all activated PPARα in luciferase assays. Two fatty acids potently activated PPARγ, a master regulator of adipocyte differentiation, with 10-oxo-12(Z)-octadecenoic acid (KetoA) having the most potency. In 3T3-L1 cells, KetoA induced adipocyte differentiation via the activation of PPARγ, and increased adiponectin production and insulin-stimulated glucose uptake. These findings suggest that fatty acids, including KetoA, generated in gut by lactic acid bacteria may be involved in the regulation of host energy metabolism. - Highlights: • Most LA-derived fatty acids from gut lactic acid bacteria potently activated PPARα. • Among tested fatty acids, KetoA and KetoC significantly activated PPARγ. • KetoA induced adipocyte differentiation via the activation of PPARγ. • KetoA enhanced adiponectin production and glucose uptake during adipogenesis.

  15. Hydroxycarboxylic acids and salts

    SciTech Connect (OSTI)

    Kiely, Donald E; Hash, Kirk R; Kramer-Presta, Kylie; Smith, Tyler N

    2015-02-24

    Compositions which inhibit corrosion and alter the physical properties of concrete (admixtures) are prepared from salt mixtures of hydroxycarboxylic acids, carboxylic acids, and nitric acid. The salt mixtures are prepared by neutralizing acid product mixtures from the oxidation of polyols using nitric acid and oxygen as the oxidizing agents. Nitric acid is removed from the hydroxycarboxylic acids by evaporation and diffusion dialysis.

  16. Regulations | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Regulations Regulations Security Reviews Click Here FOIA Appeals Click Here Whistleblower Protection Click Here Procedural Regulations Click Here Browse Title 10 Energy Click Here

  17. NATIONAL LEAD COMPANY OF OHIO

    Office of Legacy Management (LM)

    t-t AL- 1. + T fi r,y* t ,.- . NATIONAL LEAD COMPANY OF OHIO Of~~l=l i iy Ci)wp HEALTH AND SAFETY DIVISION - ANALYTICAL DEPT. ANALYTICAL DATA SHEET U-G b ;33y jl:tL G c-w &3(/y I 53 .3 Y5 .y j.os-- ! stz77y t3r1: my I CLvru' f<? 3;/ ' > j!OS ! I I I 1 P-/) ' If I , m 6.3 Lg- /&IL -q-&.+&L, /I a V Q/);: /(Lx 3L- NO. DISTRIBUTION OF COPIES 1 Analytical Laboratory (RECORD COPY) 2 Industrial Hygiene 8 Radiation Dept. Plnnt NLO-HbS-736 IREV. lo/:m4/601 - -_.-__- - ---

  18. Multi-lead heat sink

    DOE Patents [OSTI]

    Roose, L.D.

    1982-08-25

    The disclosure relates to a heat sink used to protect integrated circuits from the heat resulting from soldering them to circuit boards. A tubular housing contains a slidable member which engages somewhat inwardly extending connecting rods, each of which is rotatably attached at one end to the bottom of the housing. The other end of each rod is fastened to an expandable coil spring loop. As the member is pushed downward in the housing, its bottom edge engages and forces outward the connecting rods, thereby expanding the spring so that it will fit over an integrated circuit. After the device is in place, the member is slid upward and the spring contracts about the leads of the integrated circuit. Soldering is now conducted and the spring absorbs excess heat therefrom to protect the integrated circuit. The placement steps are repeated in reverse order to remove the heat sink for use again.

  19. Multi-lead heat sink

    DOE Patents [OSTI]

    Roose, L.D.

    1984-07-03

    The disclosure relates to a heat sink used to protect integrated circuits from the heat resulting from soldering them to circuit boards. A tubular housing contains a slidable member which engages somewhat inwardly extending connecting rods, each of which is rotatably attached at one end to the bottom of the housing. The other end of each rod is fastened to an expandable coil spring loop. As the member is pushed downward in the housing, its bottom edge engages and forces outward the connecting rods, thereby expanding the spring so that it will fit over an integrated circuit. After the device is in place, the member is slid upward and the spring contracts about the leads of the integrated circuit. Soldering is now conducted and the spring absorbs excess heat therefrom to protect the integrated circuit. The placement steps are repeated in reverse order to remove the heat sink for use again. 4 figs.

  20. Multi-lead heat sink

    DOE Patents [OSTI]

    Roose, Lars D.

    1984-01-01

    The disclosure relates to a heat sink used to protect integrated circuits from the heat resulting from soldering them to circuit boards. A tubular housing contains a slidable member which engages somewhat inwardly extending connecting rods, each of which is rotatably attached at one end to the bottom of the housing. The other end of each rod is fastened to an expandable coil spring loop. As the member is pushed downward in the housing, its bottom edge engages and forces outward the connecting rods, thereby expanding the spring so that it will fit over an integrated circuit. After the device is in place, the member is slid upward and the spring contracts about the leads of the integrated circuit. Soldering is now conducted and the spring absorbs excess heat therefrom to protect the integrated circuit. The placement steps are repeated in reverse order to remove the heat sink for use again.

  1. Charge regulation circuit

    DOE Patents [OSTI]

    Ball, Don G.

    1992-01-01

    A charge regulation circuit provides regulation of an unregulated voltage supply in the range of 0.01%. The charge regulation circuit is utilized in a preferred embodiment in providing regulated voltage for controlling the operation of a laser.

  2. Lead phosphate glass compositions for optical components

    DOE Patents [OSTI]

    Sales, Brian C.; Boatner, Lynn A.

    1987-01-01

    A lead phosphate glass to which has been added indium oxide or scandium oe to improve chemical durability and provide a lead phosphate glass with good optical properties.

  3. David Skinner Named NERSC Strategic Partnerships Lead

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    David Skinner Named NERSC Strategic Partnerships Lead David Skinner Named NERSC Strategic Partnerships Lead January 24, 2014 Contact: Linda Vu, +1 510 495 2402, lvu@lbl.gov...

  4. Downregulation of Cinnamyl Alcohol Dehydrogenase (CAD) Leads...

    Office of Scientific and Technical Information (OSTI)

    (CAD) Leads to Improved Saccharification Efficiency in Switchgrass Citation Details In-Document Search Title: Downregulation of Cinnamyl Alcohol Dehydrogenase (CAD) Leads ...

  5. Distributed Generation Lead-by-Example Resources

    Broader source: Energy.gov [DOE]

    State governments can lead by example by promoting renewable energy programs and policies. Efforts to lead by example include using renewable energy resources (including alternative fuel for...

  6. Heavy Isotopes Lead Materials Management Organization (LMMO)...

    Office of Scientific and Technical Information (OSTI)

    Heavy Isotopes Lead Materials Management Organization (LMMO) Update Citation Details In-Document Search Title: Heavy Isotopes Lead Materials Management Organization (LMMO) Update ...

  7. Low Emissions Asian Development (LEAD) Program - Bangladesh ...

    Open Energy Info (EERE)

    Low Emissions Asian Development (LEAD) Program - Bangladesh Redirect page Jump to: navigation, search REDIRECT Low Emissions Asian Development (LEAD) Program Retrieved from...

  8. Cities Leading through Energy Analysis and Planning

    Broader source: Energy.gov [DOE]

    The Cities Leading through Energy Analysis and Planning (Cities-LEAP) project delivers standardized, localized energy data and analysis that enables cities to lead clean energy innovation and...

  9. SU-E-P-09: Radiation Transmission Measurements and Evaluation of Diagnostic Lead-Based and Lead-Free Aprons

    SciTech Connect (OSTI)

    Syh, J

    2014-06-01

    Purpose: This study was conducted to ensure that various lead shield apron manufacturers provided accurate attenuation factors regardless of whether the apron was made of lead-based or lead-free equivalent material. Methods: A calibrated ionization survey meter was placed at chest height and 36 cm horizontally away from a solid water phantom on a simulator couch. Measurements were done with or without apron. Radiation field was set to 24cmx24cm with the phantom at 100cm source-to-surface distance. Irradiation time was set for 1 minute at voltages of 60, 80, 100 and 120 kVp. Current was set at 6mA. Results: Between 60 kVp and 120 kVp, the transmission through 0.50 mm of lead-based apron was between 1.0% and 6.5% with a mean value of 3.2% and a standard deviation (s.d.) of 1.4%. The transmissions through the 0.50 mm lead-free aprons were 1.0 % to 12.0% with a mean value of 6.1% and s.d. of 2.6%. At 120 kVp, the transmission value was 6.5% for 0.50 mm lead-based apron and 11.1% to 12.0% for 0.50 mm lead-free aprons. The radiation transmissions at 80 kVp, measured in two different 0.5 mm lead-free aprons, were 4.3% each. However, only 1.4% transmission was found through the lead-based apron. Overall, the radiation transmitted through the lead-based apron was 1/3 transmission of lead-free at 80kVp, and half value of lead-free aprons at 100 and 120 kVp. Conclusion: Even though lead-based and lead-free aprons all claimed to have the same lead equivalent thickness, the transmission might not be the same. The precaution was needed to exercise diligence in quality assurance program to assure adequate protection to staff who wear it during diagnostic procedures. The requirement for aprons not only should be in certain thickness to meet state regulation but also to keep reasonably achievable low exposure with the accurate labeling from manufacturers.

  10. Isotopic generator for bismuth-212 and lead-212 from radium

    DOE Patents [OSTI]

    Atcher, Robert W.; Friedman, Arnold M.; Hines, John

    1987-01-01

    A method and apparatus for providing radionuclides of bismuth-212 and lead-212. Thorium-228 and carrier solution starting material is input to a radiologically contained portion of an isotopic generator system, and radium-224 is separated from thorium-228 which is retained by a strongly basic anion exchange column. The separated radium-224 is transferred to an accessible, strongly acidic cationic exchange column. The cationic column retains the radium-224, and natural radioactive decay generates bismuth-212 and lead-212. The cationic exchange column can also be separated from the contained portion of the system and utilized without the extraordinary safety measures necessary in the contained portion. Furthermore, the cationic exchange column provides over a relatively long time period the short lived lead-212 and bismuth-212 radionuclides which are useful for a variety of medical therapies.

  11. Down-regulation of p-coumaroyl quinate/shikimate 3'-hydroxylase (C3'H) and cinnamate 4-hydroxylase (C4H) genes in the lignin biosynthetic pathway of Eucalyptus urophylla x E. grandis leads to improved sugar release

    SciTech Connect (OSTI)

    Sykes, Robert W.; Gjersing, Erica L.; Foutz, Kirk; Rottmann, William H.; Kuhn, Sean A.; Foster, Cliff E.; Ziebell, Angela; Turner, Geoffrey B.; Decker, Stephen R.; Hinchee, Maud A. W.; Davis, Mark F.

    2015-08-27

    In this study, lignocellulosic materials provide an attractive replacement for food-based crops used to produce ethanol. Understanding the interactions within the cell wall is vital to overcome the highly recalcitrant nature of biomass. One factor imparting plant cell wall recalcitrance is lignin, which can be manipulated by making changes in the lignin biosynthetic pathway. In this study, eucalyptus down-regulated in expression of cinnamate 4-hydroxylase (C4H, EC 1.14.13.11) or p-coumaroyl quinate/shikimate 3'-hydroxylase (C3'H, EC 1.14.13.36) were evaluated for cell wall composition and reduced recalcitrance.

  12. Results from the Cooler and Lead Tests

    SciTech Connect (OSTI)

    Green, Michael A

    2010-06-10

    The report presents the results of testing MICE spectrometer magnet current leads on a test apparatus that combines both the copper leads and the high temperature superconducting (HTS) leads with a single Cryomech PT415 cooler and liquid helium tank. The current is carried through the copper leads from 300 K to the top of the HTS leads. The current is then carried through the HTS leads to a feed-through from the vacuum space to the inside of a liquid helium tank. The experiment allows one to measure the performance of both cooler stages along with the performance of the leads. While the leads were powered we measured the voltage drops through the copper leads, through the HTS leads, through spliced to the feed-through, through the feed-through and through the low-temperature superconducting loop that connects one lead to the other. Measurements were made using the leads that were used in spectrometer magnet 1A and spectrometer magnet 2A. These are the same leads that were used for Superbend and Venus magnets at LBNL. The IL/A for these leads was 5.2 x 10{sup 6} m{sup -1}. The leads turned out to be too long. The same measurements were made using the leads that were installed in magnet 2B. The magnet 2B leads had an IL/A of 3.3 x 10{sup 6} A m{sup -1}. This report discusses the cooler performance and the measured electrical performance of the lead circuit that contains the copper leads and the superconducting leads. All of the HTS leads that were installed in magnet 2B were current tested using this apparatus.

  13. C-Myc Induced Compensated Cardiac Hypertrophy Increases Free Fatty Acid Utilization for the Citric Acid Cycle

    SciTech Connect (OSTI)

    Olson, Aaron; Ledee, Dolena; Iwamoto, Kate; Kajimoto, Masaki; O'Kelly-Priddy, Colleen M.; Isern, Nancy G.; Portman, Michael A.

    2013-02-01

    The protooncogene C-Myc (Myc) regulates cardiac hypertrophy. Myc promotes compensated cardiac function, suggesting that the operative mechanisms differ from those leading to heart failure. Myc regulation of substrate metabolism is a reasonable target, as Myc alters metabolism in other tissues. We hypothesize that Myc-induced shifts in substrate utilization signal and promote compensated hypertrophy. We used cardiac specific Myc-inducible C57/BL6 male mice between 4-6 months old that develop hypertrophy with tamoxifen (tam). Isolated working hearts and 13Carbon (13C )-NMR were used to measure function and fractional contributions (Fc) to the citric acid cycle by using perfusate containing 13C-labeled free fatty acids, acetoacetate, lactate, unlabeled glucose and insulin. Studies were performed at pre-hypertrophy (3-days tam, 3dMyc), established hypertrophy (7-days tam, 7dMyc) or vehicle control (cont). Non-transgenic siblings (NTG) received 7-days tam or vehicle to assess drug effect. Hypertrophy was confirmed by echocardiograms and heart weights. Western blots were performed on key metabolic enzymes. Hypertrophy occurred in 7dMyc only. Cardiac function did not differ between groups. Tam alone did not affect substrate contribution in NTG. Substrate utilization was not significantly altered in 3dMyc versus cont. The free fatty acid FC was significantly greater in 7dMyc vs cont with decreased unlabeled Fc, which is predominately exogenous glucose. Free fatty acid flux to the citric acid cycle increased while lactate flux was diminished in 7dMyc compared to cont. Total protein levels of a panel of key metabolic enzymes were unchanged; however total protein O-GlcNAcylation was increased in 7dMyc. Substrate utilization changes did not precede hypertrophy; therefore they are not the primary signal for cardiac growth in this model. Free fatty acid utilization and oxidation increase at established hypertrophy. Understanding the mechanisms whereby this change maintained

  14. {gamma}-aminobutyric acid{sub A} (GABA{sub A}) receptor regulates ERK1/2 phosphorylation in rat hippocampus in high doses of Methyl Tert-Butyl Ether (MTBE)-induced impairment of spatial memory

    SciTech Connect (OSTI)

    Zheng Gang; Zhang Wenbin; Zhang Yun; Chen Yaoming; Liu Mingchao; Yao Ting; Yang Yanxia; Zhao Fang; Li Jingxia; Huang Chuanshu; Luo Wenjing Chen Jingyuan

    2009-04-15

    Experimental and occupational exposure to Methyl Tert-Butyl Ether (MTBE) has been reported to induce neurotoxicological and neurobehavioral effects, such as headache, nausea, dizziness, and disorientation, etc. However, the molecular mechanisms involved in MTBE-induced neurotoxicity are still not well understood. In the present study, we investigated the effects of MTBE on spatial memory and the expression and function of GABA{sub A} receptor in the hippocampus. Our results demonstrated that intraventricular injection of MTBE impaired the performance of the rats in a Morris water maze task, and significantly increased the expression of GABA{sub A} receptor {alpha}1 subunit in the hippocampus. The phosphorylation of ERK1/2 decreased after the MTBE injection. Furthermore, the decreased ability of learning and the reduction of phosphorylated ERK1/2 level of the MTBE-treated rats was partly reversed by bicuculline injected 30 min before the training. These results suggested that MTBE exposure could result in impaired spatial memory. GABA{sub A} receptor may play an important role in the MTBE-induced impairment of learning and memory by regulating the phosphorylation of ERK in the hippocampus.

  15. Thermal Stability of Acetohydroxamic Acid/Nitric Acid Solutions

    SciTech Connect (OSTI)

    Rudisill, T.S.

    2002-03-13

    The transmutation of transuranic actinides and long-lived fission products in spent commercial nuclear reactor fuel has been proposed as one element of the Advanced Accelerator Applications Program. Preparation of targets for irradiation in an accelerator-driven subcritical reactor would involve dissolution of the fuel and separation of uranium, technetium, and iodine from the transuranic actinides and other fission products. The UREX solvent extraction process is being developed to reject and isolate the transuranic actinides in the acid waste stream by scrubbing with acetohydroxamic acid (AHA). To ensure that a runaway reaction will not occur between nitric acid and AHA, an analogue of hydroxyl amine, thermal stability tests were performed to identify if any processing conditions could lead to a runaway reaction.

  16. Regulators, Requirements, Statutes

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Regulators, Requirements, Statutes Regulators, Requirements, Statutes The Laboratory must comply with environmental laws and regulations that apply to Laboratory operations. Contact Environmental Communication & Public Involvement P.O. Box 1663 MS M996 Los Alamos, NM 87545 (505) 667-0216 Email Environmental laws and regulations LANL complies with more than 30 state and federal regulations and policies designed to protect human health and the environment. Regulators Regulators Environmental

  17. WPN 09-6: Lead Safe Weatherization (LSW) Additional Materials and Information

    Broader source: Energy.gov [DOE]

    To provide clarification and additional information to grantees as they implement WPN 08-6, Interim Lead-Safe Weatherization Guidance. This guidance augments, but does not replace, WPN 08-6 and builds on the foundation provided in WPN 02-6, Weatherization Activities and Federal Lead Based Paint Regulations.

  18. High-temperature superconducting current leads

    SciTech Connect (OSTI)

    Niemann, R.C.

    1995-03-01

    Use of high-temperature superconductors (HTSs) for current leads to deliver power to devices at liquid helium temperature can reduce refrigeration requirements to values significantly below those achievable with conventional leads. HTS leads are now near commercial realization. Argonne National Laboratory (ANL) has developed a sinter-forge process to fabricate current leads from bismuth-based superconductors. The current-carrying capacity of these leads is five times better than that of HTS leads made by a conventional fabrication process. ANL along with Superconductivity, Inc., has developed a 1500 ampere current lead for an existing superconducting magnetic energy storage (SMES) device. With Babcock & Wilcox Company, Argonne is creating 16-kiloampere leads for use in a 0.5 MWh SMES. In a third project Argonne performed characterization testing of a existing, proprietary conduction-cooled lead being developed by Zer Res Corp.

  19. Review of current research and activities involving characterization, abatement, and disposal of lead-containing paint films

    SciTech Connect (OSTI)

    McKnight, M.E.

    1990-05-01

    In response to a recent regulation for abating lead-based paint in housing and other environmental regulations, research projects and other activities are being conducted to provide information on procedures for carrying out abatement and maintenance of lead-containing paint films in a safe and cost-effective manner. Relevant Federal regulations, and current research projects and other activities addressing the issues are reviewed.

  20. University Competition Leads to Geothermal Breakthroughs

    Broader source: Energy.gov [DOE]

    Learn how students are leading groundbreaking research to help expand the development of America's vast geothermal energy resources.

  1. Prabhat Steps In as DAS Group Lead

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Prabhat Steps In as DAS Group Lead Prabhat Steps In as DAS Group Lead September 1, 2014 prabhat Prabhat has been named Group Lead of the Data and Analytics Services (DAS) Group at the Department of Energy's National Energy Research Scientific Computing Center (NERSC). The DAS group helps NERSC's users address data and analytics challenges arising from the increasing size and complexity of data from simulations and experiments. As the DAS Group Lead, Prabhat will play a key role in developing and

  2. Clean Lead Facility (CLF) Inventory System

    Energy Science and Technology Software Center (OSTI)

    1995-07-13

    The CLF Inventory System records shipments of clean or nonradioactive contaminated lead stored at the CLF. The Inventory System provides reports and inventory information to Facility operators. Annual, quarterly, monthly, and current inventory reports may be printed. Profile reports of each shipment of lead may also be printed for verification and documentation of lead transactions.

  3. Tracing the transport of anthropogenic lead in the atmosphere and in soils using isotopic ratios

    SciTech Connect (OSTI)

    Erel, Y.; Veron, A.; Halicz, L.

    1997-11-01

    The isotopic composition of lead in aerosols and soils in Israel is used to characterize the sources of anthropogenic lead in the region, to ascertain the isotopic composition of natural, rock-derived lead in specific areas, and to determine rates of anthropogenic lead migration in soils. The isotopic composition of lead currently emitted from cars in Israel ({sup 206}Pb/{sup 207}Pb = 1.115 {+-} 2) is controlled by alkyl-lead produced in France and Germany. In addition to petrol-lead, two more sources of anthropogenic lead can be detected in sampled aerosols; the first one has low concentrations of lead ({approximately} ng/m{sup 3}) and {sup 206}Pb/{sup 207}Pb {approximately} 1.157, and is most likely lead, emitted in Turkey, that traveled across the eastern Mediterranean basin; the second type of aerosols contains a mixture of lead emitted in several countries including Turkey, Greece, and Ukraine ({sup 206}Pb/{sup 207}Pb value of 1.155-1.160; [Pb] {approximately}20-30 ng/m{sup 3}). Anthropogenic lead is more accessible for acid leaching than natural lead, therefore, it is more labile in the soil. The isotopic composition of lead in the acid-leached fraction of near-road soil profiles records the history of alkyl-lead emission in the country. Based on changes in the isotopic composition of lead with soil depth, it is estimated that anthropogenic lead migrates into the soil at approximately 0.5 cm/y. A soil profile from a relatively remote area is less contaminated by anthropogenic lead and displays a different distribution of lead isotopic values with depth. The isotopic composition of lead suggests that natural lead in soils developed on carbonate bedrock is derived from clays, either from the rock-residue (the clay fraction in the carbonate bedrock), or from airborne clay, but not from lead released from the carbonate fraction in the rock. 44 refs., 6 figs., 2 tabs.

  4. Reproductive toxicity of low-level lead exposure in men

    SciTech Connect (OSTI)

    Telisman, Spomenka Colak, Bozo; Pizent, Alica; Jurasovic, Jasna; Cvitkovic, Petar

    2007-10-15

    Parameters of semen quality, seminal plasma indicators of secretory function of the prostate and seminal vesicles, sex hormones in serum, and biomarkers of lead, cadmium, copper, zinc, and selenium body burden were measured in 240 Croatian men 19-52 years of age. The subjects had no occupational exposure to metals and no known other reasons suspected of influencing male reproductive function or metal metabolism. After adjusting for age, smoking, alcohol, blood cadmium, and serum copper, zinc, and selenium by multiple regression, significant (P<0.05) associations of blood lead (BPb), {delta}-aminolevulinic acid dehydratase (ALAD), and/or erythrocyte protoporphyrin (EP) with reproductive parameters indicated a lead-related increase in immature sperm concentration, in percentages of pathologic sperm, wide sperm, round sperm, and short sperm, in serum levels of testosterone and estradiol, and a decrease in seminal plasma zinc and in serum prolactin. These reproductive effects were observed at low-level lead exposure (BPb median 49 {mu}g/L, range 11-149 {mu}g/L in the 240 subjects) common for general populations worldwide. The observed significant synergistic effect of BPb and blood cadmium on increasing serum testosterone, and additive effect of a decrease in serum selenium on increasing serum testosterone, may have implications on the initiation and development of prostate cancer because testosterone augments the progress of prostate cancer in its early stages.

  5. Acid distribution in phosphoric acid fuel cells

    SciTech Connect (OSTI)

    Okae, I.; Seya, A.; Umemoto, M.

    1996-12-31

    Electrolyte acid distribution among each component of a cell is determined by capillary force when the cell is not in operation, but the distribution under the current load conditions had not been clear so far. Since the loss of electrolyte acid during operation is inevitable, it is necessary to store enough amount of acid in every cell. But it must be under the level of which the acid disturbs the diffusion of reactive gases. Accordingly to know the actual acid distribution during operation in a cell is very important. In this report, we carried out experiments to clarify the distribution using small single cells.

  6. Multimedia regulated chemicals

    SciTech Connect (OSTI)

    Lee, C.C.; Huffman, G.L.; Mao, Y.L.

    1999-10-01

    This article examines those chemicals that are listed in either environmental laws or regulations. Its objective is to help readers determine which laws regulate what types of chemicals and which types of chemicals are regulated by what laws. It is multimedia in scope, describing the various chemicals that are regulated in the different media (i.e., air, water, or land).

  7. Power Marketing Administrations Leading the Nation's Transition...

    Office of Environmental Management (EM)

    electricity sector to better protect our economic and national security. As part of this process, the Energy Department ... Specific actions would include: Determining the regulation ...

  8. Apparatus and methods for purifying lead

    DOE Patents [OSTI]

    Tunison, Harmon M.

    2016-01-12

    Disclosed is an exemplary method of purifying lead which includes the steps of placing lead and a fluoride salt blend in a container; forming a first fluid of molten lead at a first temperature; forming a second fluid of the molten fluoride salt blend at a second temperature higher than the first temperature; mixing the first fluid and the second fluid together; separating the two fluids; solidifying the molten fluoride salt blend at a temperature above a melting point of the lead; and removing the molten lead from the container. In certain exemplary methods the molten lead is removed from the container by decanting. In still other exemplary methods the molten salt blend is a Lewis base fluoride eutectic salt blend, and in yet other exemplary methods the molten salt blend contains sodium fluoride, lithium fluoride, and potassium fluoride.

  9. David Skinner Named NERSC Strategic Partnerships Lead

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    David Skinner Named NERSC Strategic Partnerships Lead David Skinner Named NERSC Strategic Partnerships Lead January 24, 2014 Contact: Linda Vu, +1 510 495 2402, lvu@lbl.gov XBD201102-00089.jpg David Skinner This month, the National Energy Research Scientific Computing Center (NERSC) created a new position-Strategic Partnerships Lead, to identify new science communities that can benefit from NERSC resources. David Skinner, former head of NERSC's Outreach Software and Programming Group (OSP), has

  10. Property:LeadAgency | Open Energy Information

    Open Energy Info (EERE)

    Subproperties This property has the following 1 subproperty: R RAPIDRoadmap9-FD-k Pages using the property "LeadAgency" Showing 25 pages using this property. (previous...

  11. Facilities Electrician & Lead Electrician | Princeton Plasma...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    performing electrical work: Electrician10 years; and LEAD Electrician15 years of experience required 2. Thorough understanding of the National Electric Code. 3. Demonstrated ...

  12. Construction Branch Electrician & Lead Electrician | Princeton...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Construction Branch Electrician & Lead Electrician Department: Engineering Supervisor(s): ... devices, and assist with the construction and repair of facilities on the PPPL campus. ...

  13. Hazen Named Storage Systems Group Lead

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Hazen Named Storage Systems Group Lead Hazen Named Storage Systems Group Lead May 10, 2016 Damian Hazen Damian Hazen Damian Hazen, who has been with NERSC since 2001, has been named group lead for the Storage Systems Group. Hazen has been acting lead since last October, taking over for Jason Hick, who recently left NERSC to take a position at Los Alamos National Laboratory. During his time at NERSC, Hazen has worked primarily in the Storage Systems Group as an administrator and programmer for

  14. Compatibility of PETN with lead azide

    SciTech Connect (OSTI)

    Hurd, R.; Fronabarger, J.W.; Johnson, R.; Fleming, W.

    1983-01-01

    The compatibility of PETN with lead azide at elevated temperatures has been investigated. Ramped and isothermal DSC methods were used to obtain energies of activation at temperatures above the melting point of PETN. Mixtures were found to show exothermic activity at lower temperatures than pure PETN. High Pressure Liquid Chromatography was used to follow the decomposition of PETN and PETN/lead azide mixtures at temperatures below the melting point. Reaction below 120/sup 0/C appeared minimal, while at higher temperatures, both PETN and PETN/lead azide mixtures showed degradation. A PETN/lead azide sample exploded at or near the melting point of PETN.

  15. LEAD SUBSTITUTION AND ELIMINATION STUDY, PART II

    SciTech Connect (OSTI)

    T. MARTINEZ; M. COURNOYER

    2001-01-01

    Within the Nuclear Materials Technology Division of Los Alamos National Laboratory, lead is used as shielding for a variety of operations, including actinide chemistry, weapons production, radiochemistry, and analytical chemistry. In this study, waste minimization issues associated with replacing lead shielding with non-hazardous materials are addressed. These include institutional program available to support this effort, the hazards and accompanying controls grouped with lead shielding, operations that use lead bricks and how this effects the selection of the substitute. Life cycle management issues are also examined. As a final step, an approach to get buy-in from both technical and budget minded employees is presented.

  16. Drop In Fuels: Where the Road Leads

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... Algal Oil 8 Biomass-based Diesel: Biodiesel-ester Standalone Renewable Diesel ... 3 OC(CH 2 ) 7 CHCH(CH 2 ) 7 CH 3 O Biodiesel or Fatty Acid Methyl Ester (FAME) CH 3 ...

  17. Distributed electrical leads for thermionic converter

    DOE Patents [OSTI]

    Fitzpatrick, Gary O.; Britt, Edward J.

    1979-01-01

    In a thermionic converter, means are provided for coupling an electrical lead to at least one of the electrodes thereof. The means include a bus bar and a plurality of distributed leads coupled to the bus bar each of which penetrates through one electrode and are then coupled to the other electrode of the converter in spaced apart relation.

  18. Molecular recognition of nitrated fatty acids by PPAR[gamma

    SciTech Connect (OSTI)

    Li, Yong; Zhang, Jifeng; Schopfer, Francisco J.; Martynowski, Dariusz; Garcia-Barrio, Minerva T.; Kovach, Amanda; Suino-Powell, Kelly; Baker, Paul R.S.; Freeman, Bruce A.; Chen, Y. Eugene; Xu, H. Eric

    2010-03-08

    Peroxisome proliferator activated receptor-{gamma} (PPAR{gamma}) regulates metabolic homeostasis and adipocyte differentiation, and it is activated by oxidized and nitrated fatty acids. Here we report the crystal structure of the PPAR{gamma} ligand binding domain bound to nitrated linoleic acid, a potent endogenous ligand of PPAR{gamma}. Structural and functional studies of receptor-ligand interactions reveal the molecular basis of PPAR{gamma} discrimination of various naturally occurring fatty acid derivatives.

  19. Fan-fold shielded electrical leads

    DOE Patents [OSTI]

    Rohatgi, Rajeev R.; Cowan, Thomas E.

    1996-01-01

    Fan-folded electrical leads made from copper cladded Kapton, for example, with the copper cladding on one side serving as a ground plane and the copper cladding on the other side being etched to form the leads. The Kapton is fan folded with the leads located at the bottom of the fan-folds. Electrical connections are made by partially opening the folds of the fan and soldering, for example, the connections directly to the ground plane and/or the lead. The fan folded arrangement produces a number of advantages, such as electrically shielding the leads from the environment, is totally non-magnetic, and has a very low thermal conductivity, while being easy to fabricate.

  20. Fan-fold shielded electrical leads

    DOE Patents [OSTI]

    Rohatgi, R.R.; Cowan, T.E.

    1996-06-11

    Disclosed are fan-folded electrical leads made from copper cladded Kapton, for example, with the copper cladding on one side serving as a ground plane and the copper cladding on the other side being etched to form the leads. The Kapton is fan folded with the leads located at the bottom of the fan-folds. Electrical connections are made by partially opening the folds of the fan and soldering, for example, the connections directly to the ground plane and/or the lead. The fan folded arrangement produces a number of advantages, such as electrically shielding the leads from the environment, is totally non-magnetic, and has a very low thermal conductivity, while being easy to fabricate. 3 figs.

  1. Cryogenic Current Lead Analysis Model Program

    Energy Science and Technology Software Center (OSTI)

    1992-01-01

    CCLAMP was developed to provide a tool for tha analysis of superconducting or normal current leads used to supply electricity from a warm interface (usually room temperature) to a device at cryogenic temperatures. It determines the heat leak to the cryogenic connection and the mass flow of the cryogen (typically helium) for the lead and installation modelled. It may be used to thermally optimize a lead design for a particular application. The user provides relevantmore » geometry details to model the electrical (length, diameter, superconducting length) and heat exchanger design of the lead (heat transfer coefficient, heat transfer area). It has a transient analysis capability so that lead transients such as cool down, current ramping, flow disruptions, and control simulations can be performed.« less

  2. Lead Coolant Test Facility Development Workshop

    SciTech Connect (OSTI)

    Paul A. Demkowicz

    2005-06-01

    A workshop was held at the Idaho National Laboratory on May 25, 2005, to discuss the development of a next generation lead or lead-alloy coolant test facility. Attendees included representatives from the Generation IV lead-cooled fast reactor (LFR) program, Advanced Fuel Cycle Initiative, and several universities. Several participants gave presentations on coolant technology, existing experimental facilities for lead and lead-alloy research, the current LFR design concept, and a design by Argonne National Laboratory for an integral heavy liquid metal test facility. Discussions were focused on the critical research and development requirements for deployment of an LFR demonstration test reactor, the experimental scope of the proposed coolant test facility, a review of the Argonne National Laboratory test facility design, and a brief assessment of the necessary path forward and schedule for the initial stages of this development project. This report provides a summary of the presentations and roundtable discussions.

  3. Method for measuring lead concentrations in blood

    DOE Patents [OSTI]

    Nogar, Nicholas S.

    2001-01-01

    Method for measuring lead concentrations in blood. The present invention includes the use of resonant laser ablation to analyze .ltoreq.1 .mu.L (or equivalent mass) samples of blood for lead content. A typical finger prick, for example, yields about 10 .mu.L. Solid samples may also readily be analyzed by resonant laser ablation. The sample is placed on a lead-free, electrically conducting substrate and irradiated with a single, focused laser beam which simultaneously vaporizes, atomizes, and resonantly ionizes an analyte of interest in a sample. The ions are then sorted, collected and detected using a mass spectrometer.

  4. The risk of lead toxicity in homes with lead paint hazard

    SciTech Connect (OSTI)

    Schwartz, J.; Levin, R. )

    1991-02-01

    While lead paint has long been known to be a major source of lead poisoning, only a few small epidemiologic studies have attempted to assess directly the relative risk of lead poisoning due to the presence of lead paint. Using data from over 200,000 screening tests of children in the city of Chicago performed between 1976 and 1980, the relative risks can be quantified for children living in a major urban area. Lead paint was found to be a significant predictor of the probability of a child having lead toxicity. As expected, the reduction in leaded gasoline sales during the period reduced mean blood lead levels and increased the percentage of lead toxic children whose toxicity could be attributed to paint lead. Poisson regression models indicated that with the elimination of leaded gasoline, the relative risk of lead toxicity given lead paint exposure was 5.70 (95% CI, 4.13-7.86) during the winter and fall. The relative risk rose to 12.81 (95% CI, 7.33-22.4) in the spring and 15.8 (95% CI, 8.90-28.1) in the summer, probably due to increased exposure to window wells.

  5. HUD`s lead-based paint activities

    SciTech Connect (OSTI)

    Morony, R.

    1994-12-31

    Title X of Public Law 102-550 is a major piece of legislation for the Department having to do with lead-based paint. It changes the way the Department is going to be doing all of its work with lead-based paint in all areas except public housing. It is a mandate from Congress for a great deal of change. It is going to cause revisions in the regulations. Title X authorizes a grant program to State and local governments for the abatement of lead-based paint in low income, privately owned housing. This is an area that has not gotten attention from the Federal government before. The first series of grants have been awarded, some $46 million, to six States, three cities, and one county. The grantees have been selected for $91 million that will go to 19 winners. They received 63 applications, again from State and local governments, again for privately owned housing. There is a third grant series in this fiscal year. The applications for the $142 million are due July 5, 1994. Again, HUD is looking at privately owned housing. This is not housing that is, in most cases, federally assisted in any way.

  6. Load regulating expansion fixture

    DOE Patents [OSTI]

    Wagner, L.M.; Strum, M.J.

    1998-12-15

    A free standing self contained device for bonding ultra thin metallic films, such as 0.001 inch beryllium foils is disclosed. The device will regulate to a predetermined load for solid state bonding when heated to a bonding temperature. The device includes a load regulating feature, whereby the expansion stresses generated for bonding are regulated and self adjusting. The load regulator comprises a pair of friction isolators with a plurality of annealed copper members located therebetween. The device, with the load regulator, will adjust to and maintain a stress level needed to successfully and economically complete a leak tight bond without damaging thin foils or other delicate components. 1 fig.

  7. Load regulating expansion fixture

    DOE Patents [OSTI]

    Wagner, Lawrence M.; Strum, Michael J.

    1998-01-01

    A free standing self contained device for bonding ultra thin metallic films, such as 0.001 inch beryllium foils. The device will regulate to a predetermined load for solid state bonding when heated to a bonding temperature. The device includes a load regulating feature, whereby the expansion stresses generated for bonding are regulated and self adjusting. The load regulator comprises a pair of friction isolators with a plurality of annealed copper members located therebetween. The device, with the load regulator, will adjust to and maintain a stress level needed to successfully and economically complete a leak tight bond without damaging thin foils or other delicate components.

  8. Lead Hero Limited | Open Energy Information

    Open Energy Info (EERE)

    Hero Limited Jump to: navigation, search Name: Lead Hero Limited Place: China Product: China-based company that holds a 100% interest in XiAn Lv Jing and a 15.05% interest in...

  9. INEEL Lead Recycling in a Moratorium Environment

    SciTech Connect (OSTI)

    Kooda, K. E.; Galloway, K.; McCray, C. W.; Aitken, D. W.

    2003-02-26

    Since 1999, the Idaho National Engineering and Environmental Laboratory (INEEL) Lead Project successfully recycled over 700,000 pounds of excess INEEL lead to the private sector. On February 14, 2000, the Secretary of Energy, Bill Richardson, formalized the January 12, 2000, moratorium on recycling radioactive scrap metal that prevented the unrestricted release of recycled scrap metals to the private sector. This moratorium created significant problems for the INEEL lead recycling program and associated plans; however, through the cooperative efforts of the INEEL and Idaho State University as well as innovative planning and creative thinking the recycling issues were resolved. This collaboration has recycled over 160,000 pounds of excess lead to Idaho State University with a cost savings of over $.5M.

  10. INEEL Lead Recycling in a Moratorium Environment

    SciTech Connect (OSTI)

    Kooda, Kevin Evan; Mc Cray, Casey William; Aitken, Darren William; Galloway, Kelly

    2003-02-01

    Since 1999, the Idaho National Engineering and Environmental Laboratory (INEEL) Lead Project successfully recycled over 700,000 pounds of excess INEEL lead to the private sector. On February 14, 2000, the Secretary of Energy, Bill Richardson, formalized the January 12, 2000, moratorium on recycling radioactive scrap metal that prevented the unrestricted release of recycled scrap metals to the private sector. This moratorium created significant problems for the INEEL lead recycling program and associated plans; however, through the cooperative efforts of the INEEL and Idaho State University as well as innovative planning and creative thinking the recycling issues were resolved. This collaboration has recycled over 160,000 pounds of excess lead to Idaho State University with a cost savings of over $.5M.

  11. Measurement of the production of neighbouring jets in lead-lead...

    Office of Scientific and Technical Information (OSTI)

    Measurement of the production of neighbouring jets in lead-lead collisions at sNN2.76 TeV with the ATLAS detector Citation Details In-Document Search Title: Measurement of the...

  12. Corrosion by liquid lead and lead-bismuth: experimental results review and analysis

    SciTech Connect (OSTI)

    Zhang, Jinsuo

    2008-01-01

    Liquid metal technologies for liquid lead and lead-bismuth alloy are under wide investigation and development for advanced nuclear energy systems and waste transmutation systems. Material corrosion is one of the main issues studied a lot recently in the development of the liquid metal technology. This study reviews corrosion by liquid lead and lead bismuth, including the corrosion mechanisms, corrosion inhibitor and the formation of the protective oxide layer. The available experimental data are analyzed by using a corrosion model in which the oxidation and scale removal are coupled. Based on the model, long-term behaviors of steels in liquid lead and lead-bismuth are predictable. This report provides information for the selection of structural materials for typical nuclear reactor coolant systems when selecting liquid lead or lead bismuth as heat transfer media.

  13. NERSC seeks Computational Systems Group Lead

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    seeks Computational Systems Group Lead NERSC seeks Computational Systems Group Lead January 6, 2011 by Katie Antypas Note: This position is now closed. The Computational Systems Group provides production support and advanced development for the supercomputer systems at NERSC. Manage the Computational Systems Group (CSG) which provides production support and advanced development for the supercomputer systems at NERSC (National Energy Research Scientific Computing Center). These systems, which

  14. Nick Wright Named Advanced Technologies Group Lead

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Nick Wright Named Advanced Technologies Group Lead Nick Wright Named Advanced Technologies Group Lead February 4, 2013 Nick Nick Wright has been named head of the National Energy Research Scientific Computing Center's (NERSC) Advanced Technologies Group (ATG), which focuses on understanding the requirements of current and emerging applications to make choices in hardware design and programming models that best serve the science needs of NERSC users. ATG specializes in benchmarking, system

  15. Zerkle to lead LANL's Information Technology organization

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Zerkle to lead Information Technology organization Zerkle to lead LANL's Information Technology organization Information Technology is responsible for departmental computing, software and software applications, and computing networks and infrastructure. March 14, 2011 Los Alamos National Laboratory sits on top of a once-remote mesa in northern New Mexico with the Jemez mountains as a backdrop to research and innovation covering multi-disciplines from bioscience, sustainable energy sources, to

  16. Replica amplification of nucleic acid arrays

    DOE Patents [OSTI]

    Church, George M.; Mitra, Robi D.

    2010-08-31

    Disclosed are improved methods of making and using immobilized arrays of nucleic acids, particularly methods for producing replicas of such arrays. Included are methods for producing high density arrays of nucleic acids and replicas of such arrays, as well as methods for preserving the resolution of arrays through rounds of replication. Also included are methods which take advantage of the availability of replicas of arrays for increased sensitivity in detection of sequences on arrays. Improved methods of sequencing nucleic acids immobilized on arrays utilizing single copies of arrays and methods taking further advantage of the availability of replicas of arrays are disclosed. The improvements lead to higher fidelity and longer read lengths of sequences immobilized on arrays. Methods are also disclosed which improve the efficiency of multiplex PCR using arrays of immobilized nucleic acids.

  17. Fatty acid analogs

    DOE Patents [OSTI]

    Elmaleh, David R.; Livni, Eli

    1985-01-01

    In one aspect, a radioactively labeled analog of a fatty acid which is capable of being taken up by mammalian tissue and which exhibits an in vivo beta-oxidation rate below that with a corresponding radioactively labeled fatty acid.

  18. Mixed Acid Oxidation

    SciTech Connect (OSTI)

    Pierce, R.A.

    1999-10-26

    Several non-thermal processes have been developed to destroy organic waste compounds using chemicals with high oxidation potentials. These efforts have focused on developing technologies that work at low temperatures, relative to incineration, to overcome many of the regulatory issues associated with obtaining permits for waste incinerators. One such technique with great flexibility is mixed acid oxidation. Mixed acid oxidation, developed at the Savannah River Site, uses a mixture of an oxidant (nitric acid) and a carrier acid (phosphoric acid). The carrier acid acts as a non-volatile holding medium for the somewhat volatile oxidant. The combination of acids allows appreciable amounts of the concentrated oxidant to remain in the carrier acid well above the oxidant''s normal boiling point.

  19. PRODUCTION OF TRIFLUOROACETIC ACID

    DOE Patents [OSTI]

    Haworth, W.N.; Stacey, M.

    1949-07-19

    A method is given for the production of improved yields of trifluoroacetic acid. The compound is prepared by oxidizing m-aminobenzotrifluoride with an alkali metal or alkaline earth metal permanganate at a temperature in the range of 80 deg C to 100 deg C while dissolved ln a mixture of water with glacial acetic acid and/or trifluoroacetic acid. Preferably a mixture of water and trifluoroacetic acid ls used as the solvent.

  20. Plant fatty acid hydroxylases

    DOE Patents [OSTI]

    Somerville, Chris; Broun, Pierre; van de Loo, Frank

    2001-01-01

    This invention relates to plant fatty acyl hydroxylases. Methods to use conserved amino acid or nucleotide sequences to obtain plant fatty acyl hydroxylases are described. Also described is the use of cDNA clones encoding a plant hydroxylase to produce a family of hydroxylated fatty acids in transgenic plants. In addition, the use of genes encoding fatty acid hydroxylases or desaturases to alter the level of lipid fatty acid unsaturation in transgenic plants is described.

  1. Unique Auxin Regulation Mechanism Discovered

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Unique Auxin Regulation Mechanism Discovered Unique Auxin Regulation Mechanism Discovered Print Wednesday, 29 August 2007 00:00 The plant hormone auxin regulates many plant growth ...

  2. A Study of Lead-Acid Battery Efficiency Near Top-of-Charge

    Office of Scientific and Technical Information (OSTI)

    details of charge efficiency versus state of charge for the specific battery under test. ... details of charge efficiency versus state of charge for the specific battery under test. ...

  3. A study of lead-acid battery efficiency near top-of-charge and...

    Office of Scientific and Technical Information (OSTI)

    Resource Relation: Conference: 25. photovoltaic solar energy conference, Washington, DC ... Country of Publication: United States Language: English Subject: 14 SOLAR ENERGY; 25 ...

  4. DOE-HDBK-1084-95; Primer on Lead-Acid Storage Batteries

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of work sponsored by an agency of the United States Government. ... Effects of Discharge Rate and Temperature on Capacity and ... dangerous and can cause serious illness and death. ...

  5. Cleavage of nucleic acids

    DOE Patents [OSTI]

    Prudent, James R.; Hall, Jeff G.; Lyamichev, Victor I.; Brow, Mary Ann D.; Dahlberg, James E.

    2000-01-01

    The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.

  6. Cleavage of nucleic acids

    DOE Patents [OSTI]

    Prudent, James R.; Hall, Jeff G.; Lyamichev, Victor L.; Brow, Mary Ann D.; Dahlberg, James E.

    2007-12-11

    The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.

  7. Nucleic acid detection assays

    DOE Patents [OSTI]

    Prudent, James R.; Hall, Jeff G.; Lyamichev, Victor I.; Brow, Mary Ann; Dahlberg, James E.

    2005-04-05

    The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.

  8. Nucleic acid detection compositions

    DOE Patents [OSTI]

    Prudent, James R.; Hall, Jeff G.; Lyamichev, Victor I.; Brow, Mary Ann; Dahlberg, James L.

    2008-08-05

    The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.

  9. Cleavage of nucleic acids

    DOE Patents [OSTI]

    Prudent, James R.; Hall, Jeff G.; Lyamichev, Victor I.; Brow; Mary Ann D.; Dahlberg, James E.

    2010-11-09

    The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.

  10. Pressure reducing regulator

    DOE Patents [OSTI]

    Whitehead, John C. (Davis, CA); Dilgard, Lemoyne W. (Willits, CA)

    1995-01-01

    A pressure reducing regulator that controls its downstream or outlet pressure to a fixed fraction of its upstream or inlet pressure. The regulator includes a housing which may be of a titanium alloy, within which is located a seal or gasket at the outlet end which may be made of annealed copper, a rod, and piston, each of which may be made of high density graphite. The regulator is insensitive to temperature by virtue of being without a spring or gas sealed behind a diaphragm, and provides a reference for a system in which it is being used. The rod and piston of the regulator are constructed, for example, to have a 1/20 ratio such that when the downstream pressure is less than 1/20 of the upstream pressure the regulator opens and when the downstream pressure exceeds 1/20 of the upstream pressure the regulator closes.

  11. Pressure reducing regulator

    DOE Patents [OSTI]

    Whitehead, J.C.; Dilgard, L.W.

    1995-10-10

    A pressure reducing regulator that controls its downstream or outlet pressure to a fixed fraction of its upstream or inlet pressure is disclosed. The regulator includes a housing which may be of a titanium alloy, within which is located a seal or gasket at the outlet end which may be made of annealed copper, a rod, and piston, each of which may be made of high density graphite. The regulator is insensitive to temperature by virtue of being without a spring or gas sealed behind a diaphragm, and provides a reference for a system in which it is being used. The rod and piston of the regulator are constructed, for example, to have a 1/20 ratio such that when the downstream pressure is less than 1/20 of the upstream pressure the regulator opens and when the downstream pressure exceeds 1/20 of the upstream pressure the regulator closes. 10 figs.

  12. Removal of Radioactive Nuclides from Mo-99 Acidic Liquid Waste - 13027

    SciTech Connect (OSTI)

    Hsiao, Hsien-Ming; Pen, Ben-Li

    2013-07-01

    About 200 liters highly radioactive acidic liquid waste originating from Mo-99 production was stored at INER (Institute of Nuclear Energy Research). A study regarding the treatment of the radioactive acidic liquid waste was conducted to solve storage-related issues and allow discharge of the waste while avoiding environmental pollution. Before discharging the liquid waste, the acidity, NO{sub 3}{sup -} and Hg ions in high concentrations, and radionuclides must comply with environmental regulations. Therefore, the treatment plan was to neutralize the acidic liquid waste, remove key radionuclides to reduce the dose rate, and then remove the nitrate and mercury ions. Bench tests revealed that NaOH is the preferred solution to neutralize the high acidic waste solution and the pH of solution must be adjusted to 9?11 prior to the removal of nuclides. Significant precipitation was produced when the pH of solution reached 9. NaNO{sub 3} was the major content in the precipitate and part of NaNO{sub 3} was too fine to be completely collected by filter paper with a pore size of approximately 3 ?m. The residual fine particles remaining in solution therefore blocked the adsorption column during operation. Two kinds of adsorbents were employed for Cs-137 and a third for Sr-90 removal to minimize cost. For personnel radiation protection, significant lead shielding was required at a number of points in the process. The final process design and treatment facilities successfully treated the waste solutions and allowed for environmentally compliant discharge. (authors)

  13. Lead-induced stress corrosion cracking of Alloy 600 and 690 in high temperature water

    SciTech Connect (OSTI)

    Sakai, T.; Senjuh, T.; Aoki, K.; Shigemitsu, T.; Kishi, Y.

    1992-12-31

    Lead is one of the potential contributing impurities to the degradation of PWR steam generator tubing. Recent laboratory testing has shown that lead is a corrosive material for Alloy 600 steam generator tubing. However, it is still unknown how lead influences the corrosion of steam generator tubing, including the effect of lead concentration, solution pH, stress level and material characteristics. In this study, two kinds of experiments were performed. One was to investigate the thin film characteristic and selectively dissolved base metal elements of Alloy 600MA in high temperature solutions of different lead concentrations and pH. The other investigated the dependency of degradation of Alloy 600MA and Alloy 690TT on lead concentration and stress level in mild acidic environment, at 340{degrees}C for 2500 hrs. It was firstly demonstrated that lead-enhanced selective dissolution of nickel from alloy base metal, as a result of electrochemical reaction between lead and nickel, might cause the initiation and propagation of corrosion. Secondly, we showed that Alloy 690TT, generally very corrosion resistant material, also suffered from Pb-induced corrosion. The difference of the lead-induced stress corrosion morphology of Alloy 600MA and Alloy 690TT was also clarified.

  14. Nucleic acid detection kits

    DOE Patents [OSTI]

    Hall, Jeff G.; Lyamichev, Victor I.; Mast, Andrea L.; Brow, Mary Ann; Kwiatkowski, Robert W.; Vavra, Stephanie H.

    2005-03-29

    The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof. The present invention further relates to methods and devices for the separation of nucleic acid molecules based on charge. The present invention also provides methods for the detection of non-target cleavage products via the formation of a complete and activated protein binding region. The invention further provides sensitive and specific methods for the detection of nucleic acid from various viruses in a sample.

  15. Properly engineer lead paint removal projects

    SciTech Connect (OSTI)

    Kaelin, A.B.

    1996-01-01

    Deciding how to mitigate the hazards during lead paint removal is complex and requires consideration of many variables. Assessment of public health risk, environmental impact, and emissions potential of the operations must be considered. Additionally, the removal technique, containment system, and monitoring criteria must be developed. This article presents an integrated approach to identifying lead hazards, assessing risks to workers, the environment, and the public, developing the appropriate maintenance strategy, and selecting paint removal and containment systems. Also considered are guidelines for selecting a third party to design the overall project. This approach is based on a decision path that provides criteria for project assessment in an orderly fashion. The design of lead paint management projects in industrial applications requires consideration of the variables shown in the decision path.

  16. Resources for Utility Regulators

    SciTech Connect (OSTI)

    SEE Action

    2012-06-01

    Provides a summary of State and Local Energy Efficiency Action Network (SEE Action) information resources available to utility regulators, organized by topic.

  17. Protocol, Qualification Standard for the Site Lead Program -...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Qualification Standard for the Site Lead Program - May 2011 Protocol, Qualification Standard for the Site Lead Program - May 2011 May 2011 Qualification Standard for the Site Lead...

  18. L I NATIONAL' LEAD COMPANY OF OHIO

    Office of Legacy Management (LM)

    L I NATIONAL' LEAD COMPANY OF OHIO tJw HEALTH AND SAFETY DI"ISION - ANALITICIL DEPT. ANALYTICAL DATA SHEET _I . . NATIONAL LEAD COMPANY O F OHIO HEALTH AND SAFETY DIY1SION - ANALYTICAL DEPT. ANALYTICAL DATA SHEET NATIONA-i LEn' D COMPANY OF OHIO HEALTH AND SAFETY Dl"lSlDN - m4ALITICAL DEPT. ANALYTICAL DATA SHEET NO. I DlSTRlBUTlON OF COPIES I I A,w,lytlc.al Loboratorr (RBCORD COPI) 2 Induswlol Hvalen. B Rodhtlon Dept. 3 1 Water Trsotmmt Plant c=.z w&w hnp,., Only, - . _. NATIONAL

  19. Policy and Regulations | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Regulations Policy and Regulations map-1019833_960_720.jpg

  20. Process for the preparation of lactic acid and glyceric acid

    DOE Patents [OSTI]

    Jackson, James E [Haslett, MI; Miller, Dennis J [Okemos, MI; Marincean, Simona [Dewitt, MI

    2008-12-02

    Hexose and pentose monosaccharides are degraded to lactic acid and glyceric acid in an aqueous solution in the presence of an excess of a strongly anionic exchange resin, such as AMBERLITE IRN78 and AMBERLITE IRA400. The glyceric acid and lactic acid can be separated from the aqueous solution. Lactic acid and glyceric acid are staple articles of commerce.

  1. Coordination chemistry of two heavy metals: I, Ligand preferences in lead(II) complexation, toward the development of therapeutic agents for lead poisoning: II, Plutonium solubility and speciation relevant to the environment

    SciTech Connect (OSTI)

    Neu, M.P.

    1993-11-01

    The coordination chemistry and solution behavior of the toxic ions lead(II) and plutonium(IV, V, VI) have been investigated. The ligand pK{sub a}s and ligand-lead(II) stability constants of one hydroxamic acid and four thiohydroaxamic acids were determined. Solution thermodynamic results indicate that thiohydroxamic acids are more acidic and slightly better lead chelators than hydroxamates, e.g., N-methylthioaceto-hydroxamic acid, pK{sub a} = 5.94, log{beta}{sub 120} = 10.92; acetohydroxamic acid, pK{sub a} = 9.34, log{beta}{sub l20} = 9.52. The syntheses of lead complexes of two bulky hydroxamate ligands are presented. The X-ray crystal structures show the lead hydroxamates are di-bridged dimers with irregular five-coordinate geometry about the metal atom and a stereochemically active lone pair of electrons. Molecular orbital calculations of a lead hydroxamate and a highly symmetric pseudo octahedral lead complex were performed. The thermodynamic stability of plutonium(IV) complexes of the siderophore, desferrioxamine B (DFO), and two octadentate derivatives of DFO were investigated using competition spectrophotometric titrations. The stability constant measured for the plutonium(IV) complex of DFO-methylterephthalamide is log{beta}{sub 110} = 41.7. The solubility limited speciation of {sup 242}Pu as a function of time in near neutral carbonate solution was measured. Individual solutions of plutonium in a single oxidation state were added to individual solutions at pH = 6.0, T = 30.0, 1.93 mM dissolved carbonate, and sampled over intervals up to 150 days. Plutonium solubility was measured, and speciation was investigated using laser photoacoustic spectroscopy and chemical methods.

  2. Microorganisms for producing organic acids

    SciTech Connect (OSTI)

    Pfleger, Brian Frederick; Begemann, Matthew Brett

    2014-09-30

    Organic acid-producing microorganisms and methods of using same. The organic acid-producing microorganisms comprise modifications that reduce or ablate AcsA activity or AcsA homolog activity. The modifications increase tolerance of the microorganisms to such organic acids as 3-hydroxypropionic acid, acrylic acid, propionic acid, lactic acid, and others. Further modifications to the microorganisms increase production of such organic acids as 3-hydroxypropionic acid, lactate, and others. Methods of producing such organic acids as 3-hydroxypropionic acid, lactate, and others with the modified microorganisms are provided. Methods of using acsA or homologs thereof as counter-selectable markers are also provided.

  3. Worker lead exposures during renovation of homes with lead-based paint

    SciTech Connect (OSTI)

    Sussell, A.; Gittleman, J.; Singal, M.

    1998-11-01

    The authors evaluated lead exposures among full-time home renovators and part-time volunteers working primarily in pre-1960 homes with lead-based paint. Potentially hazardous lead exposures were measured during two tasks: exterior dry scraping and wet scraping. Maximum exposures were 120 and 63 {micro}g/m{sup 3}, respectively. Exposures during other tasks, including general repair, weatherization, exterior scraping/painting, window replacement, demolition, and plumbing, were low, as were all 13 full-shift personal exposures. Blood lead levels for full-time workers ranged up to 17.5 {micro}g/dl, with a GM of 5.2 {micro}g/dl; the GM for volunteers was 3.2 {micro}g/dl. All of the paint samples collected from work surfaces had detectable amounts of lead, with 65% of the work surfaces tested having an average lead concentration of >0.5%.

  4. Lead-203 as a label for radioimaging

    DOE Patents [OSTI]

    Srivastava, Suresh C.; Meinken, George E.

    1990-02-06

    A radiopharmaceutical composition comprising a radioactive isotope of lead (Pb-203) in combination with a pharmaceutical or an antibody or antibody fragment and a bifunctional chelating agent. These compositions are especially useful in the imaging and diagnosis of tumors and tumor metastases.

  5. Hanford Leads the Way for Greener Classrooms

    Broader source: Energy.gov [DOE]

    EM’s Richland Operations Office and contractor Mission Support Alliance (MSA) are leading the way to greener classrooms by developing a totally paperless class at the HAMMER Federal Training Facility at the Hanford site. MSA manages HAMMER on behalf of EM.

  6. Lead-203 as a label for radioimaging

    DOE Patents [OSTI]

    Srivastava, Suresh C.; Meinken, George E.

    1990-01-01

    A radiopharmaceutical composition comprising a radioactive isotope of lead (Pb-203) in combination with a pharmaceutical or an antibody or antibody fragment and a bifunctional chelating agent. These compositions are especially useful in the imaging and diagnosis of tumors and tumor metastases.

  7. Archaeological Lead Findings in the Ukraine

    SciTech Connect (OSTI)

    Danevich, F. A.; Kobychev, V. V.; Kropivyansky, B. N.; Mokina, V. M.; Nagorny, S. S.; Nikolaiko, A. S.; Poda, D. V.; Tretyak, V. I.; Kim, S. K.; Kim, H. J.; Kostezh, A. B.; Laubenstein, M.; Nisi, S.; Voronov, S. A.

    2007-03-28

    In June-August 2006 an expedition with the aim to look for low-radioactive archaeological lead at the bottom of the Black Sea, near the Crimean peninsula (Ukraine) was organised by a Korean-Ukrainian collaboration. The first samples with {approx}0.2 tons of total mass were found at a depth of 28 m among the relics of an ancient Greek ship. Their age has been dated to the first century B.C. This lead was used as ballast in the keel of the ship. The element composition of the samples was measured by means of X-ray fluorescence and ICP-MS analyses. The first preliminary limits on the 210Pb contamination of the samples are less than a few hundreds mBq/kg. The measurements were performed using gamma spectroscopy with HPGe-detectors and alpha spectroscopy with commercial {alpha}-detectors. Measurements of 40K, Th/U in the lead samples were undertaken in Kiev and in the underground laboratories of the Laboratori Nazionali del Gran Sasso (LNGS, Italy). If it was found to be radio-clean this lead could be used as high efficiency shield for ultra low-level detectors, and as raw material for growing radio-pure scintillation crystals such as PbMoO4 or PbWO4 for the search for rare processes.

  8. WIPP Documents - Federal Regulations

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Federal Regulations 40 CFR Part 191 Environmental radiation protection standards for management and disposal of spent nuclear fuel, high-level and transuranic radioactive wastes. 40 CFR Part 194 Criteria for the certification and re-certification of the Waste Isolation Pilot Plant's compliance with the 40 CFR Part 191 disposal regulations.

  9. Born energy, acid-base equilibrium, structure and interactions of end-grafted weak polyelectrolyte layers

    SciTech Connect (OSTI)

    Nap, R. J.; Tagliazucchi, M.; Szleifer, I.

    2014-01-14

    This work addresses the effect of the Born self-energy contribution in the modeling of the structural and thermodynamical properties of weak polyelectrolytes confined to planar and curved surfaces. The theoretical framework is based on a theory that explicitly includes the conformations, size, shape, and charge distribution of all molecular species and considers the acid-base equilibrium of the weak polyelectrolyte. Namely, the degree of charge in the polymers is not imposed but it is a local varying property that results from the minimization of the total free energy. Inclusion of the dielectric properties of the polyelectrolyte is important as the environment of a polymer layer is very different from that in the adjacent aqueous solution. The main effect of the Born energy contribution on the molecular organization of an end-grafted weak polyacid layer is uncharging the weak acid (or basic) groups and consequently decreasing the concentration of mobile ions within the layer. The magnitude of the effect increases with polymer density and, in the case of the average degree of charge, it is qualitatively equivalent to a small shift in the equilibrium constant for the acid-base equilibrium of the weak polyelectrolyte monomers. The degree of charge is established by the competition between electrostatic interactions, the polymer conformational entropy, the excluded volume interactions, the translational entropy of the counterions and the acid-base chemical equilibrium. Consideration of the Born energy introduces an additional energetic penalty to the presence of charged groups in the polyelectrolyte layer, whose effect is mitigated by down-regulating the amount of charge, i.e., by shifting the local-acid base equilibrium towards its uncharged state. Shifting of the local acid-base equilibrium and its effect on the properties of the polyelectrolyte layer, without considering the Born energy, have been theoretically predicted previously. Account of the Born energy leads

  10. Reversible Acid Gas Capture

    ScienceCinema (OSTI)

    Dave Heldebrant

    2012-12-31

    Pacific Northwest National Laboratory scientist David Heldebrant demonstrates how a new process called reversible acid gas capture works to pull carbon dioxide out of power plant emissions.

  11. Recovery of organic acids

    DOE Patents [OSTI]

    Verser, Dan W. (Golden, CO); Eggeman, Timothy J. (Lakewood, CO)

    2009-10-13

    A method is disclosed for the recovery of an organic acid from a dilute salt solution in which the cation of the salt forms an insoluble carbonate salt. A tertiary amine and CO.sub.2 are introduced to the solution to form the insoluble carbonate salt and a complex between the acid and an amine. A water immiscible solvent, such as an alcohol, is added to extract the acid/amine complex from the dilute salt solution to a reaction phase. The reaction phase is continuously dried and a product between the acid and the solvent, such as an ester, is formed.

  12. Recovery of organic acids

    DOE Patents [OSTI]

    Verser, Dan W. (Menlo Park, CA); Eggeman, Timothy J. (Lakewood, CO)

    2011-11-01

    A method is disclosed for the recovery of an organic acid from a dilute salt solution in which the cation of the salt forms an insoluble carbonate salt. A tertiary amine and CO.sub.2 are introduced to the solution to form the insoluble carbonate salt and a complex between the acid and an amine. A water immiscible solvent, such as an alcohol, is added to extract the acid/amine complex from the dilute salt solution to a reaction phase. The reaction phase is continuously dried and a product between the acid and the solvent, such as an ester, is formed.

  13. Lead magnesium niobate actuator for micropositioning

    DOE Patents [OSTI]

    Swift, C.D.; Bergum, J.W.

    1994-10-25

    An improved lead magnesium niobate actuator is disclosed comprising a cylindrical lead magnesium niobate crystal stack mounted in a cylindrical casing wherein a bias means, such as one or more belleville washers, is located between one end of the crystal stack and a partially closed end of the casing; and adjustment means are provided which bear against the opposite end of the crystal stack, whereby an adjustable compressive force is constantly applied against the crystal stack, whether the crystal stack is actuated in an extended position, or is in an unactuated contracted position. In a preferred embodiment, cooling ports are provided for the circulation of coolant in the actuator to cool the crystal stack, and provision is made for removal and replacement of the crystal stack without disconnecting the actuator from the external device being actuated. 3 figs.

  14. Lead magnesium niobate actuator for micropositioning

    SciTech Connect (OSTI)

    Swift, Charles D.; Bergum, John W.

    1994-01-01

    An improved lead magnesium niobate actuator is disclosed comprising a cylindrical lead magnesium niobate crystal stack mounted in a cylindrical casing wherein a bias means, such as one or more belleville washers, is located between one end of the crystal stack and a partially closed end of the casing; and adjustment means are provided which bear against the opposite end of the crystal stack, whereby an adjustable compressive force is constantly applied against the crystal stack, whether the crystal stack is actuated in an extended position, or is in an unactuated contracted position. In a preferred embodiment, cooling ports are provided for the circulation of coolant in the actuator to cool the crystal stack, and provision is made for removal and replacement of the crystal stack without disconnecting the actuator from the external device being actuated.

  15. Fermilab | Science | Particle Accelerators | Leading Accelerator Technology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Leading Accelerator Technology photo From blueprint to construction, Fermilab scientists and engineers develop particle accelerators to produce beams to take particle physics to the next level, collaborating with scientists and laboratories around the world to help build these complex machines. Researchers build accelerators to be efficient and robust along every step of the particle beam's path, from the time it's born to its termination on target. The machines themselves must be efficient,

  16. Leading By Example | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    By Example Leading By Example November 3, 2011 - 3:08pm Addthis New cool roofs installed on the Energy Department’s headquarters building in Washington DC in November, 2010. | Image credit Quentin Kruger, Energy Department New cool roofs installed on the Energy Department's headquarters building in Washington DC in November, 2010. | Image credit Quentin Kruger, Energy Department Brian Costlow Director, Office of Administration Brian Costlow has won several awards for his work recently,

  17. Leading manufacturers in the Better Buildings

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Leading manufacturers in the Better Buildings, Better Plants Program are taking on bold commitments to improve energy efficiency across their operations. Building on President Obama's Better Buildings Initiative and the Administration's broader efforts to double energy productivity by 2030, the U.S. Department of Energy (DOE) works with manufacturers to set corporate-wide energy reduction goals, improve energy management, and track and report their progress. The industrial sector accounts for

  18. Asset Recovery of Hazardous Materials Beneficial Reuse of Radiologically Encumbered Lead Stocks ''Getting the Lead Out''

    SciTech Connect (OSTI)

    LLOYD, E.R.

    2003-01-23

    Underutilized and surplus lead stocks and leaded components are a common legacy environmental problem across much of the Department of Energy (DOE) Complex. While seeking to dispose of these items through its Environmental Management Program, DOE operational programs continue to pursue contemporary mission requirements such as managing and/or storing radioactive isotopes that require lead materials for shielding. This paradox was identified in late 1999 when DOES policies for managing scrap metal were assessed. In January 2000, the Secretary of Energy directed the National Center of Excellence for Materials Recycle (NMR) to develop and implement a comprehensive lead reuse program for all of DOE. Fluor Hanford, contractor for DOE Richland Operations, subsequently contacted NMR to pilot lead reclamation and reuse at the Hanford Site, This relationship resulted in the development of a beneficial reuse pathway for lead reclaimed from spent fuel transport railcars being stored at Hanford. The 1.3 million pounds of lead in the railcars is considered radiologically encumbered due to its prior use. Further, the material was considered a mixed Resource Conservation and Recovery Act (RCRA) low-level radioactive waste that would require expensive storage or macro encapsulation to meet land disposal restrictions prior to burial. Working closely with Flour Hanford and the Office of Air, Water, and Radiation (EH-412), NMR developed a directed reuse pathway for this and other radiologically encumbered lead When derived supplemental release limits were used, the lead recovered from these railcars became eligible for reuse in shielding products to support DOE and commercial nuclear industry operations. Using this disposition pathway has saved Hanford one third of the cost of disposing of the lead and the cost of acquiring additional lead for nuclear shielding applications. Furthermore, the environmental costs associated with mining and producing new lead for shielding products and

  19. Mutant fatty acid desaturase

    DOE Patents [OSTI]

    Shanklin, John; Cahoon, Edgar B.

    2004-02-03

    The present invention relates to a method for producing mutants of a fatty acid desaturase having a substantially increased activity towards fatty acid substrates with chains containing fewer than 18 carbons relative to an unmutagenized precursor desaturase having an 18 carbon atom chain length substrate specificity. The method involves inducing one or more mutations in the nucleic acid sequence encoding the precursor desaturase, transforming the mutated sequence into an unsaturated fatty acid auxotroph cell such as MH13 E. coli, culturing the cells in the absence of supplemental unsaturated fatty acids, thereby selecting for recipient cells which have received and which express a mutant fatty acid desaturase with an elevated specificity for fatty acid substrates having chain lengths of less than 18 carbon atoms. A variety of mutants having 16 or fewer carbon atom chain length substrate specificities are produced by this method. Mutant desaturases produced by this method can be introduced via expression vectors into prokaryotic and eukaryotic cells and can also be used in the production of transgenic plants which may be used to produce specific fatty acid products.

  20. Of Refrigerators & Regulations

    Broader source: Energy.gov [DOE]

    Editor's Note: This entry has been cross-posted from The White House Blog. The President took a moment during his speech to put the debate over regulation in a different perspective.

  1. HIGH PRESSURE GAS REGULATOR

    DOE Patents [OSTI]

    Ramage, R.W.

    1962-05-01

    A gas regulator operating on the piston and feedback principle is described. The device is particularly suitable for the delicate regulation of high pressure, i.e., 10,000 psi and above, gas sources, as well as being perfectly adaptable for use on gas supplies as low as 50 psi. The piston is adjustably connected to a needle valve and the movement of the piston regulates the flow of gas from the needle valve. The gas output is obtained from the needle valve. Output pressure is sampled by a piston feedback means which, in turn, regulates the movement of the main piston. When the output is other than the desired value, the feedback system initiates movement of the main piston to allow the output pressure to be corrected or to remain constant. (AEC)

  2. Thermal spray vitrification process for the removal of lead oxide contained in organic paints

    SciTech Connect (OSTI)

    Karthikeyan, J.; Chen, J.; Bancke, G.A.; Herman, H.; Berndt, C.C.; Breslin, V.T.

    1995-12-31

    The US Environmental Protection Agency (US-EPA) regulations have necessitated the removal and containment of toxic lead from lead oxide containing paints. The Thermal Spray Vitrification Process (TSVP) is a novel technique in which a glass powder of appropriate composition is flame sprayed onto the painted surface to achieve removal and vitrification of the lead. Two different glass systems, i.e., alkali silicate and ferrous silicate, were chosen for detailed study. Appropriate amounts of raw materials were mixed, fused, quenched, ground and sieved to obtain the spray quality powders. Grit blasted mild steel coupons were used as test substrates for the spray parameter optimization studies; while those coupons with lead oxide containing organic paint were used for the lead removal experiments. The powders and deposits were investigated using Microtrac particle size analysis (for powders), optical microscopy, XRD and SEM. The remnant lead in the panel was measured using a specially prepared X-Ray Fluorescence (XRF) system. The lead leach rate was recorded as per US-EPA approved Toxicity Characteristic Leaching Procedure (TCLP). The results of this study have shown that lead oxide can be successfully removed form the paint by flame spraying a maximum of three layers of glass onto the painted surface. It is possible to obtain much higher lead removal rate with ferrous silicate glass as compared to alkali silicate glass is much higher than the ferrous silicate glass. The in situ vitrification has not been completely optimized; however, the lead containing glass coating can be remelted in situ or on site to enhance the vitrification of the lead which had been absorbed in the glass coating.

  3. Sex-based differences in gene expression in hippocampus following postnatal lead exposure

    SciTech Connect (OSTI)

    Schneider, J.S. Anderson, D.W.; Sonnenahalli, H.; Vadigepalli, R.

    2011-10-15

    The influence of sex as an effect modifier of childhood lead poisoning has received little systematic attention. Considering the paucity of information available concerning the interactive effects of lead and sex on the brain, the current study examined the interactive effects of lead and sex on gene expression patterns in the hippocampus, a structure involved in learning and memory. Male or female rats were fed either 1500 ppm lead-containing chow or control chow for 30 days beginning at weaning.Blood lead levels were 26.7 {+-} 2.1 {mu}g/dl and 27.1 {+-} 1.7 {mu}g/dl for females and males, respectively. The expression of 175 unique genes was differentially regulated between control male and female rats. A total of 167 unique genes were differentially expressed in response to lead in either males or females. Lead exposure had a significant effect without a significant difference between male and female responses in 77 of these genes. In another set of 71 genes, there were significant differences in male vs. female response. A third set of 30 genes was differentially expressed in opposite directions in males vs. females, with the majority of genes expressed at a lower level in females than in males. Highly differentially expressed genes in males and females following lead exposure were associated with diverse biological pathways and functions. These results show that a brief exposure to lead produced significant changes in expression of a variety of genes in the hippocampus and that the response of the brain to a given lead exposure may vary depending on sex. - Highlights: > Postnatal lead exposure has a significant effect on hippocampal gene expression patterns. > At least one set of genes was affected in opposite directions in males and females. > Differentially expressed genes were associated with diverse biological pathways.

  4. Lead Slowing Down Spectrometer Status Report

    SciTech Connect (OSTI)

    Warren, Glen A.; Anderson, Kevin K.; Bonebrake, Eric; Casella, Andrew M.; Danon, Yaron; Devlin, M.; Gavron, Victor A.; Haight, R. C.; Imel, G. R.; Kulisek, Jonathan A.; O'Donnell, J. M.; Weltz, Adam

    2012-06-07

    This report documents the progress that has been completed in the first half of FY2012 in the MPACT-funded Lead Slowing Down Spectrometer project. Significant progress has been made on the algorithm development. We have an improve understanding of the experimental responses in LSDS for fuel-related material. The calibration of the ultra-depleted uranium foils was completed, but the results are inconsistent from measurement to measurement. Future work includes developing a conceptual model of an LSDS system to assay plutonium in used fuel, improving agreement between simulations and measurement, design of a thorium fission chamber, and evaluation of additional detector techniques.

  5. Novel lead-iron phosphate glass

    DOE Patents [OSTI]

    Boatner, Lynn A.; Sales, Brian C.

    1989-01-01

    The invention described and claimed in the specification relates to the discovery that effective addition of Fe.sub.2 O.sub.3 to a lead phosphate glass results in a glass having enhanced chemical durability and physical stability, and consists essentially of the glass resulting from melting a mixture consisting essentially of, in weight percent, 40-66 percent PbO, 30-55 percent P.sub.2 O.sub.5 and an effective concentration up to 12 percent Fe.sub.2 O.sub.3.

  6. Novel lead-iron phosphate glass

    DOE Patents [OSTI]

    Boatner, L.A.; Sales, B.C.

    1989-07-11

    The invention described and claimed in the specification relates to the discovery that effective addition of Fe[sub 2]O[sub 3] to a lead phosphate glass results in a glass having enhanced chemical durability and physical stability, and consists essentially of the glass resulting from melting a mixture consisting essentially of, in weight percent, 40--66 percent PbO, 30--55 percent P[sub 2]O[sub 5] and an effective concentration up to 12 percent Fe[sub 2]O[sub 3].

  7. Non-lead hollow point bullet

    DOE Patents [OSTI]

    Vaughn, Norman L.; Lowden, Richard A.

    2003-04-15

    The non-lead hollow point bullet of the instant invention comprises a mixed construction slug further comprising, a monolithic metal insert having a tapered (preferred conical) hollow point tip and a tapered (preferred conical) tail protrusion, and an unsintered powdered metal composite core in tandem alignment with the insert. The core has a hollow tapered (preferred conical) cavity tip portion coupled with the tapered (preferred conical) tail protrusion on the insert. An open tip jacket envelops at least a portion of the insert and the core. The jacket is swaged at the open tip.

  8. (Lead-lithium corrosion and chemistry)

    SciTech Connect (OSTI)

    Tortorelli, P.F.

    1990-09-21

    The traveler participated in the 1990 European Workshop on Lead-Lithium Corrosion and Chemistry. Main areas of emphasis in the European liquid metal (exclusively Pb-17 at. % Li) program are now on deposition effects and corrosion-resistant surface product layers that can also serve as barriers to tritium permeation and insulators. Dr. Tortorelli also visited Harwell Laboratory to discuss innovative methods of corrosion analysis. He attended the 16th Symposium on Fusion Technology in London and the initial meeting of the Program Committee for the Second International Symposium on Fusion Nuclear Technology, which will be held in June 1991. He toured the JET facilities as part of the SOFT program.

  9. Nonaqueous solution synthesis process for preparing oxide powders of lead zirconate titanate and related materials

    DOE Patents [OSTI]

    Voigt, James A.; Sipola, Diana L.; Tuttle, Bruce A.; Anderson, Mark T.

    1999-01-01

    A process for producing powders of perovskite-type compounds which comprises mixing a metal alkoxide solution with a lead acetate solution to form a homogeneous, clear metal solution, adding an oxalic acid/n-propanol solution to this metal solution to form an easily filterable, free-flowing precursor powder and then calcining this powder. This process provides fine perovskite-phase powders with ferroelectric properties which are particularly useful in a variety of electronic applications.

  10. Nonaqueous solution synthesis process for preparing oxide powders of lead zirconate titanate and related materials

    DOE Patents [OSTI]

    Voigt, J.A.; Sipola, D.L.; Tuttle, B.A.; Anderson, M.T.

    1999-06-01

    A process is disclosed for producing powders of perovskite-type compounds which comprises mixing a metal alkoxide solution with a lead acetate solution to form a homogeneous, clear metal solution, adding an oxalic acid/n-propanol solution to this metal solution to form an easily filterable, free-flowing precursor powder and then calcining this powder. This process provides fine perovskite-phase powders with ferroelectric properties which are particularly useful in a variety of electronic applications. 4 figs.

  11. SEPARATION OF POLONIUM, PROTACTINIUM OR MIXTURES THEREOF IN AQUEOUS SOLUTION FROM BISMUTH, LEAD, ZIRCONIUM AND/OR COLUMBIUM VALUES

    DOE Patents [OSTI]

    Van Winkle, Q.; Kraus, K.A.

    1959-10-27

    A process is presented for separating polonium, protactinium, or mixtures thereof in aqueous solution from bismuth, zirconium, lead, and niobium values contained in the solution. The method comprises providing hydrochloric acid in the solution in a concentration of at least 5N. contacting the aqueous solution with a substantially waterimmiscible organic solvent such as diisopropyl ketone, and separating the aqueous phase containing the bismuth, zirconium, lead, and niobium from the organic extract phase containing the polonium, protactinium, or mixture thereof.

  12. Who's leading your process safety efforts

    SciTech Connect (OSTI)

    Bruce, S.R. (EQE International, San Francisco, CA (United States))

    1994-01-01

    To carry out a successful process safety management (PSM) program, management must complete three steps: Thoroughly understand the OSHA regulation and its benefits; Conduct a frank and complete review of current process conditions; and Communicate to all organizational levels the PSM goals. Management's leadership is the critical item to set up and maintain this safety-minded program. Instead of seeing PSM as a resource drain, operating companies should view if as a safety turnaround. This turnaround examines how and why operators continue to do business with hazardous chemicals. A better attitude toward safety repass tangible and intangible benefit such as improved profitability, employee morale and public image. A new or elaborate system isn't required, however, a new attitude is. Managers must be leaders to direct their organization toward their safety goals. This paper discusses how to implement a PSM program.

  13. New Solid Polymer Electrolytes Based on Phosphotungstic Acid | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of Energy Solid Polymer Electrolytes Based on Phosphotungstic Acid New Solid Polymer Electrolytes Based on Phosphotungstic Acid A presentation to the High Temperature Membranes Working Group meeting, May 19, 2006. linkous.pdf (2.43 MB) More Documents & Publications Lead Research and Development Activity for High Temperature, Low Relative Humidity Membrane Program Membrane Performance and Durability Overview for Automotive Fuel Cell Applications High Temperature Membrane Working Group,

  14. SU-E-P-20: Personnel Lead Apparel Integrity Inspection: Where We Are and What We Need?

    SciTech Connect (OSTI)

    Smith, S; Zhang, J; Anaskevich, L; Oates, E

    2015-06-15

    Purpose: In recent years, tremendous efforts have been devoted to radiation dose reduction, especially for patients who are directly exposed to primary radiation or receive radiopharmaceuticals. Limited efforts have been focused on those personnel who are exposed to secondary radiation while fulfilling their work responsibilities associated with diagnostic imaging and image-guided interventions. Occupational exposure is compounded in daily practice and can lead to a significant radiation dose over time. Personnel lead apparel is a well-accepted engineering control to protect healthcare workers when radiation is inevitable. The question is, do we have a nationally established program to protect personnel? This study is to investigate the lead apparel inspection programs among the USA. Methods: A series of surveys of state regulations, the University Health System Consortium, and federal regulations and regulations determined by accrediting bodies were conducted. The surveys were used to determine the current status of lead apparel programs regarding integrity inspections. Based on the survey results, a thorough program was proposed accordingly. Results: Of 50 states, seventeen states and Washington D.C. require lead apparel integrity inspections within their state regulations. Eleven of these states specify that the inspection is required on an annual basis. Two of these states require lead apron integrity checks to be performed semi-annually. Eleven out of the two hundred academic medical centers surveyed responded. The results show that the method (visually vs. fluoroscopy) used to conduct lead apparel integrity checks differ greatly amongst healthcare organizations. The FDA, EPA, CRCPD and NCRP require lead apparel integrity checks. However, the level of policies is different. A standard program is not well established and clearly there is a lack of standardization. Conclusion: A program led by legislative (state or federal government) and with specific frequency

  15. Unique Auxin Regulation Mechanism Discovered

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Unique Auxin Regulation Mechanism Discovered Print The plant hormone auxin regulates many plant growth and development processes, including shoot growth, root branching, fruit ...

  16. Reviving regulation - and antitrust

    SciTech Connect (OSTI)

    Shepherd, W.G.

    1994-06-01

    The ills of utility regulation have been overstated by interested players and at least some academics. One can have the best features of both competition and regulation by a paradigm that combines some regulation with stronger antitrust enforcement. It is now obvious that the success of deregulation actually depends crucially on whether antitrust policy is effective in preventing monopoly. In fact, antitrust policies have been extremely weak since 1980, under a deliberate Reagan administration withdrawal of enforcement. Where deregulation has led to market dominance, which antitrust cannot well cure, the policy changes of the 1980`s may have created costly and irreversible mistakes in a number of major sectors. Yet fast-paced events are currently creating a frenzy of even more deregulation, supposedly to fit new {open_quotes}revolutions{close_quotes} in technology and the impacts of large mergers. Instead it is time for particular caution in electricity.

  17. Lead paint abatement -- A technological review

    SciTech Connect (OSTI)

    Draper, A.C. III; Kapuscik, D.

    1994-12-31

    Abatement of lead from various surfaces proves to be a rapidly developing industry. Removal techniques and effectiveness varies greatly with varying substrates (wood, concrete, steel, etc.) and surface configurations including interior/exterior considerations, habitability and anticipated retrofit. Numerous technologies advances, and/or adaptations of long accepted removal techniques have recently emerged. Some of the more commonly used removal procedures including vacuum blasting, chemical stripping, scarifiers, grinders, sanders, etc. will be reviewed. Specific emphasis will be placed upon mode of application, positive and negative environmental aspects, and varying emissions generated. Personnel sampling data will be discussed with respect to associated personal protective equipment impact to derive the most cost productive environmentally conscious alternatives.

  18. Jay Srinivasan! Group Lead, Computational Systems!

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Group Lead, Computational Systems! NUG - Feb 2015 Computational Systems Update NERSC - 2014 --- 2 --- Sponsored C ompute S ystems Carver, P DSF, J GI, K BASE, H EP 8 x F DR I B /global/ scratch 4 PB /project 5 PB /home 250 TB 45 P B s tored, 2 40 P B capacity, 4 0 y ears o f community d ata HPSS 48 GB/s 2.2 P B L ocal Scratch 70 GB/s 6.4 P B L ocal Scratch 140 GB/s 80 GB/s 2 x 10 Gb 1 x 100 Gb Science D ata N etwork Vis & A naly?cs, D ata T ransfer N odes, Adv. A rch., S cience G ateways 80

  19. Lead Slowing Down Spectrometer Research Plans

    SciTech Connect (OSTI)

    Warren, Glen A.; Kulisek, Jonathan A.; Gavron, Victor; Danon, Yaron; Weltz, Adam; Harris, Jason; Stewart, T.

    2013-03-22

    The MPACT-funded Lead Slowing Down Spectrometry (LSDS) project has been evaluating the feasibility of using LSDS techniques to assay fissile isotopes in used nuclear fuel assemblies. The approach has the potential to provide considerable improvement in the assay of fissile isotopic masses in fuel assemblies compared to other non-destructive techniques in a direct and independent manner. The LSDS collaborations suggests that the next step to in empirically testing the feasibility is to conduct measurements on fresh fuel assemblies to understand investigate self-attenuation and fresh mixed-oxide (MOX) fuel rodlets so we may betterto understand extraction of masses for 235U and 239Pu. While progressing toward these goals, the collaboration also strongly suggests the continued development of enabling technology such as detector development and algorithm development, thatwhich could provide significant performance benefits.

  20. LOFT lead rod test results evaluation. [PWR

    SciTech Connect (OSTI)

    Driskell, W.B.; Tolman, E.L.

    1980-07-30

    The purpose for evaluating the LOFT Lead Rod Test (simulations of large break, loss-of-coolant accidents) data was to determine; (a) if the centerline thermocouple and fuel rod elongation sensor data show indications of the collapsed fuel rod cladding, (b) the capability of the FRAP-T5 computer code to accurately predict cladding collapse, and (c) if cladding surface thermocouples enhance fuel rod cooling. With consideration to unresolved questions on data integrity, it was concluded that: the fuel rod centerline thermocouple and elongation sensor data do show indications of the fuel rod cladding collapse; the FRAP-T5 code conservatively predicts cladding collapse; and there is an indication that cladding surface thermocouples are enhancing fuel rod cooling.

  1. Alternative Fuels Data Center: San Diego Leads in Promoting EVs

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    San Diego Leads in Promoting EVs to someone by E-mail Share Alternative Fuels Data Center: San Diego Leads in Promoting EVs on Facebook Tweet about Alternative Fuels Data Center: San Diego Leads in Promoting EVs on Twitter Bookmark Alternative Fuels Data Center: San Diego Leads in Promoting EVs on Google Bookmark Alternative Fuels Data Center: San Diego Leads in Promoting EVs on Delicious Rank Alternative Fuels Data Center: San Diego Leads in Promoting EVs on Digg Find More places to share

  2. Energy Efficiency Lead-by-Example Resources | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Lead-by-Example Resources Energy Efficiency Lead-by-Example Resources State and local governments can lead by example by promoting energy efficiency programs and policies for public facilities, equipment, and government operations. Find energy efficiency lead-by-example resources below. DOE Resource Federal Energy Management Program Publications. Other Resources Environmental Protection Agency: Lead by Example in Government Operations ACEEE's Lead By Example Initiatives National Governors

  3. Water-enhanced solubility of carboxylic acids in organic solvents and its applications to extraction processes

    SciTech Connect (OSTI)

    Starr, J.N.; King, C.J.

    1991-11-01

    The solubilities of carboxylic acids in certain organic solvents increase remarkably with an increasing amount of water in the organic phase. This phenomenon leads to a novel extract regeneration process in which the co-extracted water is selectively removed from an extract, and the carboxylic acid precipitates. This approach is potentially advantageous compared to other regeneration processes because it removes a minor component of the extract in order to achieve a large recovery of acid from the extract. Carboxylic acids of interest include adipic acid, fumaric acid, and succinic acid because of their low to moderate solubilities in organic solvents. Solvents were screened for an increase in acid solubility with increased water concentration in the organic phase. Most Lewis-base solvents were found to exhibit this increased solubility phenomena. Solvents that have a carbonyl functional group showed a very large increase in acid solubility. 71 refs., 52 figs., 38 tabs.

  4. Fuel Cell Expert Dr. Sanjiv Malhotra to Lead Energy Department...

    Energy Savers [EERE]

    Expert Dr. Sanjiv Malhotra to Lead Energy Department's Clean Energy Investment Center Fuel Cell Expert Dr. Sanjiv Malhotra to Lead Energy Department's Clean Energy Investment ...

  5. Lead Hexacyanoferrate(II) Tetrahydrate: Crystal Structure, FTIR...

    Office of Scientific and Technical Information (OSTI)

    Lead Hexacyanoferrate(II) Tetrahydrate: Crystal Structure, FTIR Spectroscopy and Thermal Decomposition Studies Citation Details In-Document Search Title: Lead Hexacyanoferrate(II) ...

  6. New Superconducting Magnet Will Lead to Next Generation of Wind...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Superconducting Magnet Will Lead to Next Generation of Wind Turbine Generators New Superconducting Magnet Will Lead to Next Generation of Wind Turbine Generators September 12, 2014 ...

  7. SEEWEC Consortium lead partner Ghent University | Open Energy...

    Open Energy Info (EERE)

    SEEWEC Consortium lead partner Ghent University Jump to: navigation, search Name: SEEWEC Consortium lead partner Ghent University Address: Sint Pietersnieuwstraat 41 Place: Gent...

  8. Low Emission Asian Development (LEAD) Program | Open Energy Informatio...

    Open Energy Info (EERE)

    Low Emission Asian Development (LEAD) Program Redirect page Jump to: navigation, search REDIRECT Low Emissions Asian Development (LEAD) Program Retrieved from "http:...

  9. Volunteers Leading Technology, A Case Study: Chewonki Renewable...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Volunteers Leading Technology, A Case Study: Chewonki Renewable Hydrogen Project Volunteers Leading Technology, A Case Study: Chewonki Renewable Hydrogen Project This presentation ...

  10. Fractionated Radiation Exposure of Rat Spinal Cords Leads to...

    Office of Scientific and Technical Information (OSTI)

    Fractionated Radiation Exposure of Rat Spinal Cords Leads to Latent Neuro-Inflammation in ... of Rat Spinal Cords Leads to Latent Neuro-Inflammation in Brain, Cognitive Deficits, ...

  11. Solar Decathlon 2015: Nation's Leading Sustainable Home Design...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Solar Decathlon 2015: Nation's Leading Sustainable Home Design Competition on the Horizon Solar Decathlon 2015: Nation's Leading Sustainable Home Design Competition on the Horizon...

  12. Bush Administration Plays Leading Role in Studying and Addressing...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Bush Administration Plays Leading Role in Studying and Addressing Global Climate Change Bush Administration Plays Leading Role in Studying and Addressing Global Climate Change...

  13. Method for isolating nucleic acids

    SciTech Connect (OSTI)

    Hurt, Jr., Richard Ashley; Elias, Dwayne A.

    2015-09-29

    The current disclosure provides methods and kits for isolating nucleic acid from an environmental sample. The current methods and compositions further provide methods for isolating nucleic acids by reducing adsorption of nucleic acids by charged ions and particles within an environmental sample. The methods of the current disclosure provide methods for isolating nucleic acids by releasing adsorbed nucleic acids from charged particles during the nucleic acid isolation process. The current disclosure facilitates the isolation of nucleic acids of sufficient quality and quantity to enable one of ordinary skill in the art to utilize or analyze the isolated nucleic acids for a wide variety of applications including, sequencing or species population analysis.

  14. Isotopic generator for bismuth-212 and lead-212 based on radium

    DOE Patents [OSTI]

    Hines, J.J.; Atcher, R.W.; Friedman, A.M.

    1985-01-30

    Disclosed are method and apparatus for providing radionuclides of bismuth-212 and lead-212. Thorium-228 and carrier solution starting material is input to a radiologically contained portion of an isotopic generator system, and radium-224 is separated from thorium-228 which is retained by a strongly basic anion exchange column. The separated radium-224 is transferred to an accessible, strongly acidic cationic exchange column. The cationic column retains the radium-224, and natural radioactive decay generates bismuth-212 and lead-212. The cationic exchange column can also be separated from the contained portion of the system and utilized without the extraordinary safety measures necessary in the contained portion. Furthermore, the cationic exchange column provides over a relatively long time period the short lived lead-212 and bismuth-212 radionuclides which are useful for a variety of medical therapies.

  15. Report on the evaluation of the tritium producing burnable absorber rod lead test assembly. Revision 1

    SciTech Connect (OSTI)

    1997-03-01

    This report describes the design and fabrication requirements for a tritium-producing burnable absorber rod lead test assembly and evaluates the safety issues associated with tritium-producing burnable absorber rod irradiation on the operation of a commercial light water reactor. The report provides an evaluation of the tritium-producing burnable absorber rod design and concludes that irradiation can be performed within U.S. Nuclear Regulatory Commission regulations applicable to a commercial pressurized light water reactor.

  16. Ultrasound in lead-bismuth eutectic

    SciTech Connect (OSTI)

    Dierckx, M.; Van Dyck, D.

    2011-07-01

    The Belgian Nuclear Research Centre (SCK.CEN) is in the process of designing MYRRHA, a new multi-purpose irradiation facility to replace the ageing BR2. MYRRHA is a fast spectrum reactor cooled with lead-bismuth eutectic (LBE). As liquid metal is opaque to visual light, ultrasonic measurement techniques are selected to fulfill essential tasks that, according to our assessment, will be demanded by licensing authorities, in particular: fuel assembly identification and localization of a lost fuel assembly. To that end, a considerable research effort at SCK.CEN is devoted to study ultrasonic propagation in LBE. As ultrasonic experiments in LBE are elaborate and expensive to set up, we are particularly interested in to what extent experiments in water can be extrapolated to LBE - one of the main focuses of this article. We describe and present results of a first experiment with this goal which shows that the signal to noise ratio is better in LBE and that we even see small diffuse reflections up to 40 deg. off normal. On the other hand, we do not see internal reflections in stainless steel objects in LBE which we do in water. Therefore, we conclude that experiments in water can be used to validate algorithms for LBE on the condition that they do not rely on internal reflections. We also present solutions to tackle the essential tasks: fuel assembly identification and lost object localization. The requirements for the ultrasonic equipment implementing these solutions are also discussed. (authors)

  17. Cell cycle nucleic acids, polypeptides and uses thereof

    DOE Patents [OSTI]

    Gordon-Kamm, William J.; Lowe, Keith S.; Larkins, Brian A.; Dilkes, Brian R.; Sun, Yuejin

    2007-08-14

    The invention provides isolated nucleic acids and their encoded proteins that are involved in cell cycle regulation. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. The present invention provides methods and compositions relating to altering cell cycle protein content, cell cycle progression, cell number and/or composition of plants.

  18. Get the lead out! removing lead-based paint on hydro plant structures

    SciTech Connect (OSTI)

    Johnson, M.L.

    1996-05-01

    This article describes a hydroblasting technology used to remove lead-based surface coatings from the steel associated with the flood gates at the Wirtz Dam. Using this technology and an advanced moisture-cured urethane coating, the Lower Colorado River Authority was able to save more than $250,000 in materials, labor, and waste disposal costs.

  19. Method for construction of bacterial strains with increased succinic acid production

    DOE Patents [OSTI]

    Donnelly, Mark I.; Sanville-Millard, Cynthia; Chatterjee, Ranjini

    2000-01-01

    A fermentation process for producing succinic acid is provided comprising selecting a bacterial strain that does not produce succinic acid in high yield, disrupting the normal regulation of sugar metabolism of said bacterial strain, and combining the mutant bacterial strain and selected sugar in anaerobic conditions to facilitate production of succinic acid. Also provided is a method for changing low yield succinic acid producing bacteria to high yield succinic acid producing bacteria comprising selecting a bacterial strain having a phosphotransferase system and altering the phosphotransferase system so as to allow the bacterial strain to simultaneously metabolize different sugars.

  20. Microsoft Word - Final Lead Assembly SA.doc

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... of European Fabrication of Lead MOX Assemblies. ...... 20 Table 4. Comparison of Human Health ...

  1. Building Standards Lead-by-Example Resources | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Standards Lead-by-Example Resources Building Standards Lead-by-Example Resources State and local governments can lead by example by promoting energy efficiency programs and policies for public facilities, equipment, and government operations. Find building standards lead-by-example resources below. DOE Resource National Best Practices Manual For Building High Performance Schools. Other Resource Roadmap to Green Government Buildings

  2. Optical high acidity sensor

    DOE Patents [OSTI]

    Jorgensen, B.S.; Nekimken, H.L.; Carey, W.P.; O`Rourke, P.E.

    1997-07-22

    An apparatus and method for determining acid concentrations in solutions having acid concentrations of from about 0.1 Molar to about 16 Molar is disclosed. The apparatus includes a chamber for interrogation of the sample solution, a fiber optic light source for passing light transversely through the chamber, a fiber optic collector for receiving the collimated light after transmission through the chamber, a coating of an acid resistant polymeric composition upon at least one fiber end or lens, the polymeric composition in contact with the sample solution within the chamber and having a detectable response to acid concentrations within the range of from about 0.1 Molar to about 16 Molar, a measurer for the response of the polymeric composition in contact with the sample solution, and a comparer of the measured response to predetermined standards whereby the acid molarity of the sample solution within the chamber can be determined. Preferably, a first lens is attached to the end of the fiber optic light source, the first lens adapted to collimate light from the fiber optic light source, and a second lens is attached to the end of the fiber optic collector for focusing the collimated light after transmission through the chamber. 10 figs.

  3. Optical high acidity sensor

    DOE Patents [OSTI]

    Jorgensen, Betty S.; Nekimken, Howard L.; Carey, W. Patrick; O'Rourke, Patrick E.

    1997-01-01

    An apparatus and method for determining acid concentrations in solutions having acid concentrations of from about 0.1 Molar to about 16 Molar is disclosed. The apparatus includes a chamber for interrogation of the sample solution, a fiber optic light source for passing light transversely through the chamber, a fiber optic collector for receiving the collimated light after transmission through the chamber, a coating of an acid resistant polymeric composition upon at least one fiber end or lens, the polymeric composition in contact with the sample solution within the chamber and having a detectable response to acid concentrations within the range of from about 0.1 Molar to about 16 Molar, a measurer for the response of the polymeric composition in contact with the sample solution, and, a comparer of the measured response to predetermined standards whereby the acid molarity of the sample solution within the chamber can be determined. Preferably, a first lens is attached to the end of the fiber optic light source, the first lens adapted to collimate light from the fiber optic light source, and a second lens is attached to the end of the fiber optic collector for focusing the collimated light after transmission through the chamber.

  4. Nucleic acids, compositions and uses thereof

    DOE Patents [OSTI]

    Preston, III, James F.; Chow, Virginia; Nong, Guang; Rice, John D.; St. John, Franz J.

    2012-02-21

    The subject invention provides at least one nucleic acid sequence encoding an aldouronate-utilization regulon isolated from Paenibacillus sp. strain JDR-2, a bacterium which efficiently utilizes xylan and metabolizes aldouronates (methylglucuronoxylosaccharides). The subject invention also provides a means for providing a coordinately regulated process in which xylan depolymerization and product assimilation are coupled in Paenibacillus sp. strain JDR-2 to provide a favorable system for the conversion of lignocellulosic biomass to biobased products. Additionally, the nucleic acid sequences encoding the aldouronate-utilization regulon can be used to transform other bacteria to form organisms capable of producing a desired product (e.g., ethanol, 1-butanol, acetoin, 2,3-butanediol, 1,3-propanediol, succinate, lactate, acetate, malate or alanine) from lignocellulosic biomass.

  5. Nucleic acid compositions and the encoding proteins

    DOE Patents [OSTI]

    Preston, III, James F.; Chow, Virginia; Nong, Guang; Rice, John D.; St. John, Franz J.

    2014-09-02

    The subject invention provides at least one nucleic acid sequence encoding an aldouronate-utilization regulon isolated from Paenibacillus sp. strain JDR-2, a bacterium which efficiently utilizes xylan and metabolizes aldouronates (methylglucuronoxylosaccharides). The subject invention also provides a means for providing a coordinately regulated process in which xylan depolymerization and product assimilation are coupled in Paenibacillus sp. strain JDR-2 to provide a favorable system for the conversion of lignocellulosic biomass to biobased products. Additionally, the nucleic acid sequences encoding the aldouronate-utilization regulon can be used to transform other bacteria to form organisms capable of producing a desired product (e.g., ethanol, 1-butanol, acetoin, 2,3-butanediol, 1,3-propanediol, succinate, lactate, acetate, malate or alanine) from lignocellulosic biomass.

  6. MULTI-TUBE POWER LEADS TOWER FOR BEPCII IR MAGNETS.

    SciTech Connect (OSTI)

    JIA,L.X.; ZHANG,X.B.; WANG,L.; WANG,T.H.; YAO,Z.L.

    2004-05-11

    A power lead tower containing the multi-tube power leads is designed and under fabrication for the superconducting IR quadrupole magnets in the Beijing Electron Position Collider Upgrade (BEPCII). The lead tower consists of six pairs of gas-cooled leads for seven superconducting coils at various operating currents. The power lead is designed in a modular fashion, which can be easily applied to suit different operating current. The end copper block of the tube lead has a large cold mass that provide a large time constant in case of cooling flow interruption. A novel cryogenic electrical isolator is used for the leads.

  7. Src regulates the activity of SIRT2

    SciTech Connect (OSTI)

    Choi, You Hee; Kim, Hangun; Lee, Sung Ho; Jin, Yun-Hye; Lee, Kwang Youl

    2014-07-25

    Highlights: Src decreases the protein levels of Sirt2. Src inhibitor and knockdown of Src increase the protein levels of Sirt2. Src interacts with and phosphorylates Sirt2. Src regulate the activity of Sirt2. - Abstract: SIRT2 is a mammalian member of the Sirtuin family of NAD{sup +}-dependent protein deacetylases. The tyrosine kinase Src is involved in a variety of cellular signaling pathways, leading to the induction of DNA synthesis, cell proliferation, and cytoskeletal reorganization. The function of SIRT2 is modulated by post-translational modifications; however, the precise molecular signaling mechanism of SIRT2 through interactions with c-Src has not yet been established. In this study, we investigated the potential regulation of SIRT2 function by c-Src. We found that the protein levels of SIRT2 were decreased by c-Src, and subsequently rescued by the addition of a Src specific inhibitor, SU6656, or by siRNA-mediated knockdown of c-Src. The c-Src interacts with and phosphorylates SIRT2 at Tyr104. c-Src also showed the ability to regulate the deacetylation activity of SIRT2. Investigation on the phosphorylation of SIRT2 suggested that this was the method of c-Src-mediated SIRT2 regulation.

  8. ELECTRON EMISSION REGULATING MEANS

    DOE Patents [OSTI]

    Brenholdt, I.R.

    1957-11-19

    >An electronic regulating system is described for controlling the electron emission of a cathode, for example, the cathode in a mass spectrometer. The system incorporates a transformer having a first secondary winding for the above-mentioned cathode and a second secondary winding for the above-mentioned cathode and a second secondary winding load by grid controlled vacuum tubes. A portion of the electron current emitted by the cathode is passed through a network which develops a feedback signal. The system arrangement is completed by using the feedback signal to control the vacuum tubes in the second secondary winding through a regulator tube. When a change in cathode emission occurs, the feedback signal acts to correct this change by adjusting the load on the transformer.

  9. Regulation of Meiotic Recombination

    SciTech Connect (OSTI)

    Gregory p. Copenhaver

    2011-11-09

    Meiotic recombination results in the heritable rearrangement of DNA, primarily through reciprocal exchange between homologous chromosome or gene conversion. In plants these events are critical for ensuring proper chromosome segregation, facilitating DNA repair and providing a basis for genetic diversity. Understanding this fundamental biological mechanism will directly facilitate trait mapping, conventional plant breeding, and development of genetic engineering techniques that will help support the responsible production and conversion of renewable resources for fuels, chemicals, and the conservation of energy (1-3). Substantial progress has been made in understanding the basal recombination machinery, much of which is conserved in organisms as diverse as yeast, plants and mammals (4, 5). Significantly less is known about the factors that regulate how often and where that basal machinery acts on higher eukaryotic chromosomes. One important mechanism for regulating the frequency and distribution of meiotic recombination is crossover interference - or the ability of one recombination event to influence nearby events. The MUS81 gene is thought to play an important role in regulating the influence of interference on crossing over. The immediate goals of this project are to use reverse genetics to identify mutants in two putative MUS81 homologs in the model plant Arabidopsis thaliana, characterize those mutants and initiate a novel forward genetic screen for additional regulators of meiotic recombination. The long-term goal of the project is to understand how meiotic recombination is regulated in higher eukaryotes with an emphasis on the molecular basis of crossover interference. The ability to monitor recombination in all four meiotic products (tetrad analysis) has been a powerful tool in the arsenal of yeast geneticists. Previously, the qrt mutant of Arabidopsis, which causes the four pollen products of male meiosis to remain attached, was developed as a facile system

  10. Potential involvement of kinesin-1 in the regulation of subcellular localization of Girdin

    SciTech Connect (OSTI)

    Muramatsu, Aya; Enomoto, Atsushi; Kato, Takuya; Weng, Liang; Kuroda, Keisuke; Asai, Naoya; Asai, Masato; Mii, Shinji; Takahashi, Masahide

    2015-08-07

    Girdin is an actin-binding protein that has multiple functions in postnatal neural development and cancer progression. We previously showed that Girdin is a regulator of migration for neuroblasts born from neural stem cells in the subventricular zone (SVZ) and the dentate gyrus of the hippocampus in the postnatal brain. Despite a growing list of Girdin-interacting proteins, the mechanism of Girdin-mediated migration has not been fully elucidated. Girdin interacts with Disrupted-In-Schizophrenia 1 and partitioning-defective 3, both of which have been shown to interact with the kinesin microtubule motor proteins. Based on this, we have identified that Girdin also interacts with kinesin-1, a member of neuronal kinesin proteins. Although a direct interaction of Girdin and kinesin-1 has not been determined, it is of interest to find that Girdin loss-of-function mutant mice with the mutation of a basic amino acid residue-rich region (Basic mut mice) exhibit limited interaction with kinesin-1. Furthermore, expression of a kinesin-1 mutant with motor defects, leads to Girdin mislocalization. Finally, consistent with previous studies on the role of kinesin proteins in trafficking a cell–cell adhesion molecule N-cadherin, Basic mut mice showed an aberrant expression pattern of N-cadherin in migrating SVZ neuroblasts. These findings suggest a potential role of Girdin/kinesin-1 interaction in the regulation of neuroblast migration in the postnatal brain. - Highlights: • Girdin is a regulator of migration for neuroblasts in the postnatal brain. • Girdin interacts with kinesin-1, a member of neuronal kinesin proteins. • Girdin mutant mice showed an aberrant expression of N-cadherin in neuroblasts.

  11. Plant fatty acid hydroxylase

    DOE Patents [OSTI]

    Somerville, Chris; van de Loo, Frank

    2000-01-01

    The present invention relates to the identification of nucleic acid sequences and constructs, and methods related thereto, and the use of these sequences and constructs to produce genetically modified plants for the purpose of altering the composition of plant oils, waxes and related compounds.

  12. Synthesis of acid addition salt of delta-aminolevulinic acid from 5-bromo levulinic acid esters

    DOE Patents [OSTI]

    Moens, Luc

    2003-06-24

    A process of preparing an acid addition salt of delta-aminolevulinc acid comprising: a) dissolving a lower alkyl 5-bromolevulinate and hexamethylenetetramine in a solvent selected from the group consisting of water, ethyl acetate, chloroform, acetone, ethanol, tetrahydrofuran and acetonitrile, to form a quaternary ammonium salt of the lower alkyl 5-bromolevulinate; and b) hydrolyzing the quaternary ammonium salt with an inorganic acid to form an acid addition salt of delta-aminolevulinic acid.

  13. Interrelationship of Program Regulations and Financial Assistance Regulations

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1980-04-24

    The purpose of this Order is to set forth the interrelationship between all program regulations which will result in assistance awards (Program Regulations) and the Department of Energy Assistance Regulations (DOE-AR, 10 CRF Part 600), including procedures for exceptions, deviations or waivers.

  14. Stress response of lead-exposed rainbow trout (Oncorhynchus mykiss) during swimming performance and hypoxia challenges

    SciTech Connect (OSTI)

    Phillips, K.A. |; Caldwell, C.A.; Sandheinrich, M.B.

    1995-12-31

    Contaminants often invoke a stress response in aquatic organisms, and may compromise their capacity to respond to secondary stressors. This may reduce growth, reproduction and survival. The authors objectives were to assess the effects of lead and secondary stressors on hematology and blood chemistry of rainbow trout. After a 7 to 8-week aqueous exposure to Pb(100{micro}g/L), rainbow trout were challenged with forced swimming or hypoxia. Lead significantly reduced concentrations of 5-aminolevulinic acid dehydratase (ALAD), but not other constituents in the blood. Lead did not affect the swimming endurance of the fish. Hematocrit, mean cell hemoglobin content, and mean cell volume were significantly lower in Pb-exposed trout following the swimming challenge. Although hypoxia resulted in increased hematocrit and plasma glucose concentrations, there were no significant differences between the Pb and control groups. Hypoxia did not affect plasma chloride concentrations, although concentrations increased in Pb-exposed trout. There was no difference in lactic acid concentrations between Pb-exposed and control fish after forced swimming or hypoxia.

  15. EFFECTS OF NITRIC ACID ON CRITICALITY SAFETY ANALYSIS

    SciTech Connect (OSTI)

    Williamson, B.

    2011-08-18

    As nitric acid molarity is increased, there are two competing phenomena affecting the reactivity of the system. First, there is interaction between each of the 10 wells in the basket-like insert. As the molarity of the nitric acid solution is increased (it moves from 100% water to 100% HNO{sub 3}), the hydrogen atom density decreases by about 80%. However, it remains a relatively efficient moderator. The moderating ratio of nitric acid is about 90% that of water. As the media between the wells is changed from 100% water to 100% nitric acid, the density of the media increases by 50%. A higher density typically leads to a better reflector. However, when the macroscopic scattering cross sections are considered, nitric acid is a much worse reflector than water. The effectiveness of nitric acid as a reflector is about 40% that of water. Since the media between the wells become a worse reflector and still remains an effective moderator, interaction between the wells increases. This phenomenon will cause reactivity to increase as nitric acid molarity increases. The seond phenomenon is due to the moderating ratio changing in the high concentration fissile-nitric acid solution in the 10 wells. Since the wells contain relatively small volumes of high concentration solutions, a small decrease in moderating power has a large effect on reactivity. This is due to the fact that neutrons are more likely to escape the high concentration fissile solution before causing another fission event. The result of this phenomenon is that as nitric acid molarity increases, reactivity decreases. Recent studies have shown that the second phenomenon is indeed the dominating force in determining reactivity changes in relation to nitric acid molarity changes. When considering the system as a whole, as nitric acid molarity increases, reactivity decreases.

  16. Self-regulating valve

    DOE Patents [OSTI]

    Humphreys, D.A.

    1982-07-20

    A variable, self-regulating valve having a hydraulic loss coefficient proportional to a positive exponential power of the flow rate. The device includes two objects in a flow channel and structure which assures that the distance between the two objects is an increasing function of the flow rate. The range of spacing between the objects is such that the hydraulic resistance of the valve is an increasing function of the distance between the two objects so that the desired hydraulic loss coefficient as a function of flow rate is obtained without variation in the flow area.

  17. Weatherization Rules and Regulations Resources

    Broader source: Energy.gov [DOE]

    Federal regulations provide the framework for the Weatherization Assistance Program. These rules and regulations give state and local weatherization programs guidelines to provide the energy efficiency improvements to low-income dwellings.

  18. Fatty acid-producing hosts

    DOE Patents [OSTI]

    Pfleger, Brian F; Lennen, Rebecca M

    2013-12-31

    Described are hosts for overproducing a fatty acid product such as a fatty acid. The hosts include an exogenous nucleic acid encoding a thioesterase and, optionally, an exogenous nucleic acid encoding an acetyl-CoA carboxylase, wherein an acyl-CoA synthetase in the hosts are functionally delected. The hosts prefereably include the nucleic acid encoding the thioesterase at an intermediate copy number. The hosts are preferably recominantly stable and growth-competent at 37.degree. C. Methods of producing a fatty acid product comprising culturing such hosts at 37.degree. C. are also described.

  19. Acid diffusion through polyaniline membranes

    SciTech Connect (OSTI)

    Su, T.M.; Huang, S.C.; Conklin, J.A.

    1995-12-01

    Polyaniline membranes in the undoped (base) and doped (acid) forms are studied for their utility as pervaporation membranes. The separation of water from mixtures of propionic acid, acetic acid and formic acid have been demonstrated from various feed compositions. Doped polyaniline displays an enhanced selectivity of water over these organic acids as compared with undoped polyaniline. For as-cast polyaniline membranes a diffusion coefficient (D) on the order of 10{sup -9} cm{sup 2}/sec has been determined for the flux of protons through the membranes using hydrochloric acid.

  20. Regulators, Boards, Councils - Hanford Site

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Regulators, Boards, Councils Hanford Advisory Board Hanford Natural Resource Trustee Council Environmental Protection Agency Washington State Department of Ecology Defense...

  1. Engineer Russ Feder leads development of diagnostic tools for...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Engineer Russ Feder leads development of diagnostic tools for US ITER as physicist Dave ... Feder leads PPPL's development of all diagnostic tools for US ITER, which manages U.S. ...

  2. Zarb Appointed to Lead the Federal Energy Administration | National Nuclear

    National Nuclear Security Administration (NNSA)

    Security Administration | (NNSA) Zarb Appointed to Lead the Federal Energy Administration Zarb Appointed to Lead the Federal Energy Administration Washington, DC President Ford appoints Frank Zarb to be the first Administrator of the newly created Federal Energy Agency

  3. PNNL Breakthrough Leads to Less Foreign Oil, More American Jobs...

    Energy Savers [EERE]

    PNNL Breakthrough Leads to Less Foreign Oil, More American Jobs PNNL Breakthrough Leads to Less Foreign Oil, More American Jobs October 17, 2011 - 2:50pm Addthis A highly efficient ...

  4. DOE ZERH Second Leading Builder Round Table Meeting Report |...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    DOE ZERH Second Leading Builder Round Table Meeting Report On October 23rd-24th, 2014, the ZERH program held its Second Leading Production Builder Round Table Meeting in Suwanee, ...

  5. Energy Department to Lead Workshop on Tribal Renewable Energy...

    Office of Environmental Management (EM)

    Lead Workshop on Tribal Renewable Energy Development in Oklahoma Energy Department to Lead Workshop on Tribal Renewable Energy Development in Oklahoma June 1, 2015 - 9:50am Addthis ...

  6. Fatal pediatric poisoning from leaded paint--Wisconsin, 1990

    SciTech Connect (OSTI)

    Not Available

    1991-03-29

    Although fatal lead poisoning among children occurs rarely in the United States, it represents a medical and public health emergency. This report summarizes the investigation of a child who died from poisoning associated with ingestion of lead-based paint.

  7. GE leads the way in photonics research | GE Global Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GE continues leading role in photonics industry - from LED to digital x-ray Click to email ... GE continues leading role in photonics industry - from LED to digital x-ray Danielle ...

  8. Crystal structure and compressibility of lead dioxide up to 140...

    Office of Scientific and Technical Information (OSTI)

    Crystal structure and compressibility of lead dioxide up to 140 GPa Citation Details In-Document Search Title: Crystal structure and compressibility of lead dioxide up to 140 GPa ...

  9. Temperature controlled high voltage regulator

    DOE Patents [OSTI]

    Chiaro, Jr., Peter J.; Schulze, Gerald K.

    2004-04-20

    A temperature controlled high voltage regulator for automatically adjusting the high voltage applied to a radiation detector is described. The regulator is a solid state device that is independent of the attached radiation detector, enabling the regulator to be used by various models of radiation detectors, such as gas flow proportional radiation detectors.

  10. Getting the lead out: Citizen involvement in the Williamsburg Bridge lead paint removal project

    SciTech Connect (OSTI)

    Forker, T.R.

    1997-08-01

    This paper examines the process and results of citizen involvement in developing new environmental control and compliance procedures used by the New York City Department of Transportation (NYC DOT) for lead paint removal on the Williamsburg Bridge and other structures. As a case study of the effects of public involvement in environmental decision-making, the study identifies and discusses the factors that produced failures or successes in satisfying the citizen`s concerns about health risks and the effectiveness of the selected pollution control technology.

  11. Alternative Fuels Data Center: Smoky Mountains Leads the Way in

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    Implementing Alternative Fuels Smoky Mountains Leads the Way in Implementing Alternative Fuels to someone by E-mail Share Alternative Fuels Data Center: Smoky Mountains Leads the Way in Implementing Alternative Fuels on Facebook Tweet about Alternative Fuels Data Center: Smoky Mountains Leads the Way in Implementing Alternative Fuels on Twitter Bookmark Alternative Fuels Data Center: Smoky Mountains Leads the Way in Implementing Alternative Fuels on Google Bookmark Alternative Fuels Data

  12. Retrofit Program Lead-by-Example Resources | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Retrofit Program Lead-by-Example Resources Retrofit Program Lead-by-Example Resources State and local governments can lead by example by promoting energy efficiency programs and policies for public facilities, equipment, and government operations. Find retrofit program lead-by-example resources below. Local Government Climate and Energy Strategy Series: Energy Efficiency in Local Government Operations: A Guide to Developing and Implementing Greenhouse Gas Reduction Programs ACEEE: Comprehensive

  13. Procurement Standards Lead-by-Example Resources | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Procurement Standards Lead-by-Example Resources Procurement Standards Lead-by-Example Resources State and local governments can lead by example by promoting energy efficiency programs and policies for public facilities, equipment, and government operations. Find procurement standards lead-by-example resources below. DOE Resource Energy-Efficient Product Procurement. Other Resources ENERGY STAR®: All Certified Products New York State Energy Research and Development Authority: Procurement

  14. 2015 Leading Builder Round Table Report | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Leading Builder Round Table Report 2015 Leading Builder Round Table Report The nation is on the cusp of a dramatic movement to zero energy ready homes. This includes statewide codes, large developments, and a growing amount of commitment to the DOE Zero Energy Ready Home program. Much of this progress can be attributed to a small contingent of our nation's leading builders who are demonstrating the technical, cost, and design feasibility for this level of excellence At the 2015 Leading Builder

  15. Cities Leading Through Energy Analysis and Planning Infographic |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Cities Leading Through Energy Analysis and Planning Infographic Cities Leading Through Energy Analysis and Planning Infographic The Cities Leading through Energy Analysis and Planning (Cities-LEAP) project delivers standardized, localized energy data and analysis that enables cities to lead clean energy innovation and integrate strategic energy analysis into decision making. Two Cities-LEAP infographics catalog the programs and tools currently supporting local

  16. NNSA Leads Conference on Nonproliferation Research and Development |

    National Nuclear Security Administration (NNSA)

    National Nuclear Security Administration | (NNSA) Leads Conference on Nonproliferation Research and Development December 04, 2008 WASHINGTON, D.C. -- The National Nuclear Security Administration (NNSA) concluded a conference showcasing the leading edge nuclear nonproliferation research being conducted at premier universities and by industry experts. The University and Industry Technical Interchange (UITI) included over 75 presentations by leading researchers to showcase nuclear detection

  17. Lubrication with boric acid additives

    DOE Patents [OSTI]

    Erdemir, Ali

    2000-01-01

    Self-lubricating resin compositions including a boric acid additive and a synthetic polymer including those thermoset materials.

  18. Competition law and British natural gas regulation

    SciTech Connect (OSTI)

    Black, A.J.

    1992-01-01

    British Gas (BG) is a seriously successful monopolist which, since its 1986 privatisation, is acing increased regulation by the Office of Gas Supply (OFGAS). OFGAS is the first public body specifically created to regulate a European gas industry. It employs a rate-capping formula instead of the more labour intensive rate-of-retum method favoured in North America. Despite initial criticisms, OFGAS has surprised industry observers with efficacious results. This article succinctly discusses the process of natural gas industry privatisation in the United Kingdom (U.K.) and the development of a British type of [open quotes]open access.[close quotes] Contemporary British gas regulation is a distinct paradigm involving the privatisation of a vertically integrated pipeline system coupled with an altemative regulatory method. These regulatory results include lower prices for core customers and the promotion of third party direct sales within the U.K. Since Britain leads the European Community (E.C.) in common carriage provisions, the regulatory r6gime here provides a benchmark for the other Member States.

  19. Lab Breakthrough: Lead-free Solder | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Lead-free Solder Lab Breakthrough: Lead-free Solder May 24, 2012 - 10:45am Addthis Iver Anderson, senior metallurgist at Ames Laboratory, explains the importance of lead-free solder in taking hazardous lead out of the environment by eliminating it from discarded computers and electronics that wind up in landfills. Anderson led a team that developed a tin-silver-copper replacement for traditional lead-tin solder that has been adopted by more than 50 companies worldwide. View the entire Lab

  20. Lead contamination in the Mallard (Anas platyrhynchos) in Italy

    SciTech Connect (OSTI)

    Tirelli, E.; Maestrini, N.; Govoni, S.; Catelli, E.

    1996-05-01

    The main cause of lead poisoning in waterfowl is due to ingestion of spent lead shot in areas of high hunting pressure . Italian literature on this subject is very scarce and the few available studies concern episodic cases. to contribute to the assessment of the impact of lead shot in waterfowl in Italy, systematic research has been carried out on shorebirds caught for ringing in Tiscany and are continuing on dabbling and diving ducks by checking the presence of lead in blood samples and lead shot in the gizzard. This study targets the mallard duck. 17 refs., 1 fig., 1 tab.

  1. Pantothenic acid biosynthesis in zymomonas

    DOE Patents [OSTI]

    Tao, Luan; Tomb, Jean-Francois; Viitanen, Paul V.

    2014-07-01

    Zymomonas is unable to synthesize pantothenic acid and requires this essential vitamin in growth medium. Zymomonas strains transformed with an operon for expression of 2-dehydropantoate reductase and aspartate 1-decarboxylase were able to grow in medium lacking pantothenic acid. These strains may be used for ethanol production without pantothenic acid supplementation in seed culture and fermentation media.

  2. Carboxylic acid sorption regeneration process

    DOE Patents [OSTI]

    King, C.J.; Poole, L.J.

    1995-05-02

    Carboxylic acids are sorbed from aqueous feedstocks into an organic liquid phase or onto a solid adsorbent. The acids are freed from the sorbent phase by treating it with aqueous alkylamine thus forming an alkylammonium carboxylate which is dewatered and decomposed to the desired carboxylic acid and the alkylamine. 10 figs.

  3. Carboxylic acid sorption regeneration process

    DOE Patents [OSTI]

    King, C. Judson; Poole, Loree J.

    1995-01-01

    Carboxylic acids are sorbed from aqueous feedstocks into an organic liquid phase or onto a solid adsorbent. The acids are freed from the sorbent phase by treating it with aqueous alkylamine thus forming an alkylammonium carboxylate which is dewatered and decomposed to the desired carboxylic acid and the alkylamine.

  4. Oxygen-­dependent regulation of bacterial lipid production

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Lemmer, Kimberly C.; Dohnalkova, Alice C.; Noguera, Daniel R.; Donohue, Timothy J.

    2015-05-02

    Understanding the mechanisms of lipid accumulation in microorganisms is important for several reasons. In addition to providing insight into assembly of biological membranes, lipid accumulation has important applications in the production of renewable fuels and chemicals. The photosynthetic bacterium Rhodobacter sphaeroides is an attractive organism to study lipid accumulation, as it has the somewhat unique ability to increase membrane production at low O₂ tensions. Under these conditions, R. sphaeroides develops invaginations of the cytoplasmic membrane to increase its membrane surface area for housing of the membrane-bound components of its photosynthetic apparatus. Here we use fatty acid levels as a reportermore » of membrane lipid content. We show that, under low-O₂ and anaerobic conditions, the total fatty acid content per cell increases 3-fold. We also find that the increases in the amount of fatty acid and photosynthetic pigment per cell are correlated as O₂ tensions or light intensity are changed. To ask if lipid and pigment accumulation were genetically separable, we analyzed strains with mutations in known photosynthetic regulatory pathways. While a strain lacking AppA failed to induce photosynthetic pigment-protein complex accumulation, it increased fatty acid content under low O2 conditions. We also found that an intact PrrBA pathway is required for low O2-induced fatty acid accumulation. In conclusion, our findings suggest a previously unknown role of R. sphaeroides transcriptional regulators in increasing fatty acid and phospholipid accumulation in response to decreased O₂ tension.« less

  5. Composition for nucleic acid sequencing

    DOE Patents [OSTI]

    Korlach, Jonas; Webb, Watt W.; Levene, Michael; Turner, Stephen; Craighead, Harold G.; Foquet, Mathieu

    2008-08-26

    The present invention is directed to a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the polymerization reaction is measured on a molecule of nucleic acid, i.e. the activity of a nucleic acid polymerizing enzyme on the template nucleic acid molecule to be sequenced is followed in real time. The sequence is deduced by identifying which base is being incorporated into the growing complementary strand of the target nucleic acid by the catalytic activity of the nucleic acid polymerizing enzyme at each step in the sequence of base additions. A polymerase on the target nucleic acid molecule complex is provided in a position suitable to move along the target nucleic acid molecule and extend the oligonucleotide primer at an active site. A plurality of labelled types of nucleotide analogs are provided proximate to the active site, with each distinguishable type of nucleotide analog being complementary to a different nucleotide in the target nucleic acid sequence. The growing nucleic acid strand is extended by using the polymerase to add a nucleotide analog to the nucleic acid strand at the active site, where the nucleotide analog being added is complementary to the nucleotide of the target nucleic acid at the active site. The nucleotide analog added to the oligonucleotide primer as a result of the polymerizing step is identified. The steps of providing labelled nucleotide analogs, polymerizing the growing nucleic acid strand, and identifying the added nucleotide analog are repeated so that the nucleic acid strand is further extended and the sequence of the target nucleic acid is determined.

  6. Invasive cleavage of nucleic acids

    DOE Patents [OSTI]

    Prudent, James R.; Hall, Jeff G.; Lyamichev, Victor I.; Brow, Mary Ann D.; Dahlberg, James E.

    2002-01-01

    The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.

  7. Invasive cleavage of nucleic acids

    DOE Patents [OSTI]

    Prudent, James R.; Hall, Jeff G.; Lyamichev, Victor I.; Brow, Mary Ann D.; Dahlberg, James E.

    1999-01-01

    The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.

  8. Vermont Hazardous Waste Management Regulations | Open Energy...

    Open Energy Info (EERE)

    Hazardous Waste Management Regulations Jump to: navigation, search OpenEI Reference LibraryAdd to library Legal Document- RegulationRegulation: Vermont Hazardous Waste Management...

  9. ELECTRICAL REGULATING APPARATUS INCLUDING AN IONIC CURRENT REGULATOR

    DOE Patents [OSTI]

    Brackney, H.W.

    1958-08-12

    An apparatus is described for regulating the operation of an electromagmetic charged particle separator lt consists of an electrical circuit for innproving the regulation of the accelerating voltage of a calutron when the ionic current regulator control means is disconnected. The novel circuit arrangement connects the input of the ionic current regulator to a voltage divider. in association with a second voltage regulatora to furnish an accelerating voltage output which remains constant at a mean value instead of zero as has been the practice.

  10. Telomere length in children environmentally exposed to low-to-moderate levels of lead

    SciTech Connect (OSTI)

    Pawlas, Natalia; Płachetka, Anna; Kozłowska, Agnieszka; Broberg, Karin; Kasperczyk, Sławomir

    2015-09-01

    Shorter relative telomere length in peripheral blood is a risk marker for some types of cancers and cardiovascular diseases. Several environmental hazards appear to shorten telomeres, and this shortening may predispose individuals to disease. The aim of the present cross-sectional study was to assess the effect of environmental exposure to lead on relative telomere length (rTL) in children. A cohort of 99 8-year-old children was enrolled from 2007–2010. Blood lead concentrations (B-Pb) were measured by graphite furnace atomic absorption spectrometry, and blood rTL was measured by quantitative PCR. The geometric mean of B-Pb was 3.28 μg/dl (range: 0.90–14.2), and the geometric mean of rTL was 1.08 (range: 0.49–2.09). B-Pb was significantly inversely associated with rTL in the children (r{sub S} = − 0.25, p = 0.013; in further analyses both log-transformed-univariate regression analysis β = − 0.13, p = 0.026, and R{sup 2}adj 4%; and β = − 0.12, p = 0.056 when adjusting for mothers' smoking during pregnancy, Apgar score, mother's and father's ages at delivery, sex and mother's education, R{sup 2}adj 12%, p = 0.011). The effect of lead remained significant in children without prenatal tobacco exposure (N = 87, r{sub S} = − 0.24, p = 0.024; in further analyses, β = − 0.13, p = 0.029, and R{sup 2}adj 4%). rTL was not affected by sex, the concentrations of other elements in the blood (i.e., cadmium and selenium concentrations), or oxidative injury parameters (total antioxidant status, 8-hydroxydeoxyguanosine and thiobarbituric acid-reactive substances). Lead exposure in childhood appears to be associated with shorter telomeres, which might contribute to diseases, such as cardiovascular disease. The inverse association between blood lead level and the telomeres in children emphasizes the importance of further reducing lead levels in the environment. - Highlights: • This cross-sectional study analyzes the association between environmental lead exposure

  11. Synthesis of amino acids

    DOE Patents [OSTI]

    Davis, J.W. Jr.

    1979-09-21

    A method is described for synthesizing amino acids preceding through novel intermediates of the formulas: R/sub 1/R/sub 2/C(OSOC1)CN, R/sub 1/R/sub 2/C(C1)CN and (R/sub 1/R/sub 2/C(CN)O)/sub 2/SO wherein R/sub 1/ and R/sub 2/ are each selected from hydrogen and monovalent hydrocarbon radicals of 1 to 10 carbon atoms. The use of these intermediates allows the synthesis steps to be exothermic and results in an overall synthesis method which is faster than the synthesis methods of the prior art.

  12. Unique Auxin Regulation Mechanism Discovered

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Unique Auxin Regulation Mechanism Discovered Unique Auxin Regulation Mechanism Discovered Print Wednesday, 29 August 2007 00:00 The plant hormone auxin regulates many plant growth and development processes, including shoot growth, root branching, fruit ripening, tropisms, and flowering. But how such a simple molecule elicits such a variety of cellular responses has been a mystery. An important breakthrough came in 2005, wh en a conserved plant protein known as TIR1 (part of a protein destruction

  13. Nucleic Acid Detection Methods

    DOE Patents [OSTI]

    Smith, Cassandra L.; Yaar, Ron; Szafranski, Przemyslaw; Cantor, Charles R.

    1998-05-19

    The invention relates to methods for rapidly determining the sequence and/or length a target sequence. The target sequence may be a series of known or unknown repeat sequences which are hybridized to an array of probes. The hybridized array is digested with a single-strand nuclease and free 3'-hydroxyl groups extended with a nucleic acid polymerase. Nuclease cleaved heteroduplexes can be easily distinguish from nuclease uncleaved heteroduplexes by differential labeling. Probes and target can be differentially labeled with detectable labels. Matched target can be detected by cleaving resulting loops from the hybridized target and creating free 3-hydroxyl groups. These groups are recognized and extended by polymerases added into the reaction system which also adds or releases one label into solution. Analysis of the resulting products using either solid phase or solution. These methods can be used to detect characteristic nucleic acid sequences, to determine target sequence and to screen for genetic defects and disorders. Assays can be conducted on solid surfaces allowing for multiple reactions to be conducted in parallel and, if desired, automated.

  14. Nucleic acid detection methods

    DOE Patents [OSTI]

    Smith, C.L.; Yaar, R.; Szafranski, P.; Cantor, C.R.

    1998-05-19

    The invention relates to methods for rapidly determining the sequence and/or length a target sequence. The target sequence may be a series of known or unknown repeat sequences which are hybridized to an array of probes. The hybridized array is digested with a single-strand nuclease and free 3{prime}-hydroxyl groups extended with a nucleic acid polymerase. Nuclease cleaved heteroduplexes can be easily distinguish from nuclease uncleaved heteroduplexes by differential labeling. Probes and target can be differentially labeled with detectable labels. Matched target can be detected by cleaving resulting loops from the hybridized target and creating free 3-hydroxyl groups. These groups are recognized and extended by polymerases added into the reaction system which also adds or releases one label into solution. Analysis of the resulting products using either solid phase or solution. These methods can be used to detect characteristic nucleic acid sequences, to determine target sequence and to screen for genetic defects and disorders. Assays can be conducted on solid surfaces allowing for multiple reactions to be conducted in parallel and, if desired, automated. 18 figs.

  15. Ozone and acid rain

    SciTech Connect (OSTI)

    Not Available

    1987-10-09

    The roles of ozone and other oxidizing agents are discussed. The major polluting emissions are SO/sub 2/, NO, and volatile organic chemicals. In the usual ambient concentrations, these substances are relatively harmless. However, when SO/sub 2/ and NO are oxidized, they are converted into more acid, more toxic, substances. Oxidants, including OH, H/sub 2/O/sub 2/, HO/sub 2/, and organic peroxides, arise out of complex photochemistry that involves the ozone, the nitrogen oxides, and volatile organic chemicals. Were SO/sub 2/ the only pollutant, most of it would escape unchanged to the western Atlantic Ocean where it would be so diluted as to have no effect. At present about 35 percent of the SO/sub 2/ produced in the United States leaves the continent. In contrast, because of higher rates of reaction with oxidants, most of the NO is converted into nitric acid and deposited on land. The nitrogen oxides are involved in the production of ozone, some of which is naturally present. But particularly in urban settings where concentrations of NO/sub x/ are elevated and volatile organic chemicals such as those in gasoline are present, ozone concentrations may rise to levels deleterious to health. The Environmental Protection Agency has set standards for levels not to be exceeded, but nearly half of urban communities are not in compliance. The NO/sub x/ involved in the formation of urban ozone comes mostly from vehicular emissions.

  16. Energy Secretary Bodman Leads US Delegation to International Energy Agency

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Ministerial | Department of Energy Leads US Delegation to International Energy Agency Ministerial Energy Secretary Bodman Leads US Delegation to International Energy Agency Ministerial May 2, 2005 - 12:41pm Addthis PARIS, FRANCE -- Secretary of Energy Samuel W. Bodman this week is leading the U.S. Delegation to the Ministerial Meeting of the International Energy Agency (IEA), being held in Paris. Secretary Bodman will emphasize three principles at the IEA Ministerial -- that energy security

  17. Reversible and irreversible ion migration processes in lead halide

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    perovskites for photovoltaics | MIT-Harvard Center for Excitonics Reversible and irreversible ion migration processes in lead halide perovskites for photovoltaics March 9, 2016 at 4:30 PM/36-462 Eric Hoke Stanford University, Draper Laboratory hoke-eric Lead hybrid perovskites are a promising family of photovoltaic absorber materials that have achieved power conversion efficiencies of over 20%. Lead halide perovskites are ionic materials with a low lattice energy which are unusual properties

  18. EERE Success Story- Hydropower Fellowship Program Leading Students to

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Industry Careers | Department of Energy Hydropower Fellowship Program Leading Students to Industry Careers EERE Success Story- Hydropower Fellowship Program Leading Students to Industry Careers April 20, 2016 - 12:15pm Addthis EERE Success Story— Hydropower Fellowship Program Leading Students to Industry Careers The Hydro Research Foundation's (HRF) Hydro Fellowship Program allowed outstanding up-and-coming student fellows to conduct hydropower-related research-all made possible by a

  19. Kjiersten Fagnan Appointed NERSC/JGI Engagement Lead

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Kjiersten Fagnan Named NERSC/JGI Engagement Lead Kjiersten Fagnan Appointed NERSC/JGI Engagement Lead September 1, 2014 fagnan.jpg Kjiersten Fagnan has been named the NERSC/JGI Engagement Lead for Joint Genome Institute (JGI) computational and data analysis efforts carried out at the Department of Energy's (DOE) National Energy Research Scientific Computing Center (NERSC). Fagnan, who holds a Ph.D. in Applied Mathematics from the University of Washington, started at NERSC as a petascale postdoc

  20. Bush Administration Plays Leading Role in Studying and Addressing Global

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Climate Change | Department of Energy Plays Leading Role in Studying and Addressing Global Climate Change Bush Administration Plays Leading Role in Studying and Addressing Global Climate Change February 27, 2007 - 3:49pm Addthis Washington, DC - Continuing to take the lead in addressing global climate change, Energy Secretary Samuel Bodman, Environmental Protection Agency (EPA) Administrator Stephen Johnson, and National Oceanic and Atmospheric Administration (NOAA) Administrator Vice

  1. Sec. Herrington Leads Delegation in Response to Chernobyl Accident...

    National Nuclear Security Administration (NNSA)

    Photo Gallery Jobs Apply for Our Jobs Our Jobs Working at NNSA Blog Home About Us Our History NNSA Timeline Sec. Herrington Leads Delegation in Response to ... Sec....

  2. Combined Heat and Power System Enables 100% Reliability at Leading...

    Office of Environmental Management (EM)

    - Case Study, 2013 Combined Heat and Power System Enables 100% Reliability at Leading ... uninterrupted energy services to TECO customers in the event of a prolonged grid outage. ...

  3. Lasing in robust cesium lead halide perovskite nanowires (Journal...

    Office of Scientific and Technical Information (OSTI)

    Title: Lasing in robust cesium lead halide perovskite nanowires Authors: Eaton, Samuel W. ; Lai, Minliang ; Gibson, Natalie A. ; Wong, Andrew B. ; Dou, Letian ; Ma, Jie ; Wang, ...

  4. EM Leads Successful Workshop Supporting Fukushima Cleanup | Department...

    Broader source: Energy.gov (indexed) [DOE]

    officials leading the cleanup of the Fukushima Daiichi Nuclear Power Plant site and surrounding area, this time addressing priorities identified by Japan's government agencies. ...

  5. West Africa Emerges as Leading Region in Africa for Renewable...

    Open Energy Info (EERE)

    West Africa Emerges as Leading Region in Africa for Renewable Energy and Energy Efficiency Home > Groups > Clean and Renewable Energy Dc's picture Submitted by Dc(266) Contributor...

  6. Solar Test Facility Upgrades Complete, Leading to Better Sandia...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Test Facility Upgrades Complete, Leading to Better Sandia Capabilities to Support Power ... Applications National Solar Thermal Test Facility Nuclear Energy Systems ...

  7. Establishment of the Heavy Isotopes Lead Materials Management...

    Office of Scientific and Technical Information (OSTI)

    Materials Management Organization (LMMO) Citation Details In-Document Search Title: Establishment of the Heavy Isotopes Lead Materials Management Organization (LMMO) Authors: ...

  8. Moderate Doping Leads to High Performance of Semiconductor/Insulator...

    Office of Scientific and Technical Information (OSTI)

    Title: Moderate Doping Leads to High Performance of SemiconductorInsulator Polymer Blend Transistors Authors: Lu, Guanghao ; Blakesley, James ; Himmelberger, Scott ; Pingel, ...

  9. Mainzer taps Gendron, Ehli to lead Power and Corporate Strategy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Mainzer-taps-Gendron-Ehli-to-lead-Power-and-Corporate-Strategy Sign In About | Careers | Contact | Investors | bpa.gov Search News & Us Expand News & Us Projects & Initiatives...

  10. Method of manufacturing lead electrodes for storage cells

    DOE Patents [OSTI]

    Jonville, P.; Stoehr, H.; Beccu, K.D.

    1975-09-23

    A method of manufacturing electrodes for lead storage batteries is described. Molten lead or lead alloy is deposited on a felt of glass fibers by spraying in a molten state to fill the space between the fibers of the felt to form an electrically conductive zone defining electrode contacts. A mass of powdered lead-based material is introduced into the felt by filtration for subsequently producing an active electrode mass by at least one electrochemical transformation. The felt is then cut into individual electrodes. (auth)

  11. Nano Design Works: Industry's contact for emerging tech, leading...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Works: Industry's contact for emerging tech, leading tools, and experts Argonne's Nano Design Works gives companies and entrepreneurs the solutions that enable technological ...

  12. Research Led by Sandia Reveals Leading-Edge Erosion Significantly...

    Broader source: Energy.gov (indexed) [DOE]

    Laboratories revealed that leading-edge erosion on wind turbine blades can have a detrimental effect on wind turbine aerodynamic performance within the second year of operation. ...

  13. Indonesia-Low Emissions Asian Development (LEAD) Program | Open...

    Open Energy Info (EERE)

    the growth of greenhouse gas emissions. The LEAD program supports and enhances country-led development programs, plans, and policies, and complements efforts of other...

  14. Thailand-Low Emissions Asian Development (LEAD) Program | Open...

    Open Energy Info (EERE)

    the growth of greenhouse gas emissions. The LEAD program supports and enhances country-led development programs, plans, and policies, and complements efforts of other...

  15. Philippines-Low Emissions Asian Development (LEAD) Program |...

    Open Energy Info (EERE)

    the growth of greenhouse gas emissions. The LEAD program supports and enhances country-led development programs, plans, and policies, and complements efforts of other...

  16. Papua New Guinea-Low Emissions Asian Development (LEAD) Program...

    Open Energy Info (EERE)

    the growth of greenhouse gas emissions. The LEAD program supports and enhances country-led development programs, plans, and policies, and complements efforts of other...

  17. India-Low Emissions Asian Development (LEAD) Program | Open Energy...

    Open Energy Info (EERE)

    the growth of greenhouse gas emissions. The LEAD program supports and enhances country-led development programs, plans, and policies, and complements efforts of other...

  18. Cambodia-Low Emissions Asian Development (LEAD) Program | Open...

    Open Energy Info (EERE)

    the growth of greenhouse gas emissions. The LEAD program supports and enhances country-led development programs, plans, and policies, and complements efforts of other...

  19. Bangladesh-Low Emissions Asian Development (LEAD) Program | Open...

    Open Energy Info (EERE)

    the growth of greenhouse gas emissions. The LEAD program supports and enhances country-led development programs, plans, and policies, and complements efforts of other...

  20. Vietnam-Low Emissions Asian Development (LEAD) Program | Open...

    Open Energy Info (EERE)

    the growth of greenhouse gas emissions. The LEAD program supports and enhances country-led development programs, plans, and policies, and complements efforts of other...

  1. Malaysia-Low Emissions Asian Development (LEAD) Program | Open...

    Open Energy Info (EERE)

    the growth of greenhouse gas emissions. The LEAD program supports and enhances country-led development programs, plans, and policies, and complements efforts of other...

  2. Nepal-Low Emissions Asian Development (LEAD) Program | Open Energy...

    Open Energy Info (EERE)

    the growth of greenhouse gas emissions. The LEAD program supports and enhances country-led development programs, plans, and policies, and complements efforts of other...

  3. Laos-Low Emissions Asian Development (LEAD) Program | Open Energy...

    Open Energy Info (EERE)

    the growth of greenhouse gas emissions. The LEAD program supports and enhances country-led development programs, plans, and policies, and complements efforts of other...

  4. Surface Plasmon Instability Leading to Emission of Radiation...

    Office of Scientific and Technical Information (OSTI)

    Title: Surface Plasmon Instability Leading to Emission of Radiation. Abstract not provided. Authors: Gumbs, Godfrey ; Iurov, Andrii ; Huang, Danhong ; Pan, Wei Publication Date: ...

  5. Lead Research and Development Activity for High Temperature,...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Temperature, Low Relative Humidity Membrane Program Lead Research and Development Activity for High Temperature, Low Relative Humidity Membrane Program A presentation to the High ...

  6. Ames Laboratory to Lead New Research Effort to Address Shortages...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Ames Laboratory to Lead New Research Effort to Address Shortages in Rare Earth and Other ... These critical materials, including many rare earth elements, are essential for ...

  7. Testing your home for lead in paint, dust, and soil

    SciTech Connect (OSTI)

    1998-10-01

    This publication is for anyone who is considering having a home or residence tested for lead in paint, dust, or soil by a professional. It explains the technical aspects of lead testing without overwhelming the reader. The first section tells why you would test for lead, the approaches for testing for lead, and what information you will get from each approach. The second section answers specific questions about how paint, soil, and dust sampling are conducted by the professional in your home. Finally, the last section answers other questions about testing, including questions about home test kits and testing of water and ceramics.

  8. Westinghouse Selects Bill Keeley To Lead Strategic Planning and...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    TRU Solutions LLC (WTS) has appointed Bill Keeley to lead the integrated functions of Strategic Planning and Communication at the Waste Isolation Pilot Plant (WIPP). WTS is the...

  9. Robert C. Seamans, Jr. Appointed to Lead Nuclear Weapons Program...

    National Nuclear Security Administration (NNSA)

    C. Seamans, Jr. Appointed to Lead Nuclear Weapons Program | National Nuclear Security Administration Facebook Twitter Youtube Flickr RSS People Mission Managing the Stockpile...

  10. Solar Decathlon 2015: Nation's Leading Sustainable Home Design...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Decathlon 2015: Nation's Leading Sustainable Home Design Competition on the Horizon Solar ... Richard King Richard King Director, Solar Decathlon KEY FACTS 2015 Solar Decathlon to kick ...

  11. Deputy Secretary of Energy Reviews Leading Nuclear Counterterrorism...

    National Nuclear Security Administration (NNSA)

    Deputy Secretary of Energy Reviews Leading Nuclear Counterterrorism Assets at Andrews Air Force Base September 09, 2009 WASHINGTON, D.C. - Deputy Secretary of Energy Daniel Poneman ...

  12. Fatigue of extracted lead zirconate titanate multilayer actuators...

    Office of Scientific and Technical Information (OSTI)

    Testing of large prototype lead zirconate titanate (PZT) stacks presents substantial technical challenges to electronic testing systems, so an alternative approach that uses ...

  13. University Teams Lead Innovative Solar Research Projects | Department...

    Office of Environmental Management (EM)

    University Teams Lead Innovative Solar Research Projects August 28, 2012 - 2:55pm Addthis A concentrating solar power system in Albuquerque, New Mexico. | Photo by Randy Montoya...

  14. NNSA Computers Lead Global List | National Nuclear Security Administra...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Computers Lead Global List | National Nuclear Security Administration Facebook Twitter Youtube Flickr RSS People Mission Managing the Stockpile Preventing Proliferation Powering...

  15. Y-12 leads the way in specialized machining

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    leads the way in specialized machining The original nine major buildings at Y-12, five "Alpha" buildings and four "Beta" buildings were originally built to house calutrons to...

  16. NREL Names New Executives to Lead Bioenergy, Bioscience and Energy...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Names New Executives to Lead Bioenergy, Bioscience and Energy Systems Integration Facility ... NREL has named Tom Foust, a nine-year NREL veteran, as its National Bioenergy Center ...

  17. Data, Feedback, & Awareness Lead to Big Energy Savings

    Broader source: Energy.gov (indexed) [DOE]

    Data, Feedback, & Awareness Lead to Big Energy Savings The Navy Region Southwest Metro San ... organized energy awareness program centered on energy data gathering and distribution. ...

  18. Vapor cooled current lead for cryogenic electrical equipment

    DOE Patents [OSTI]

    Vansant, James H.

    1983-01-01

    Apparatus and method are provided for conducting electric current to cryogenic electrical equipment devices. A combination of inner and outer tubes together form a plurality of hollow composite tubes housed in a sheath. Top and bottom block mounting means are fitted to hold the composite tubes and are affixed to the ends of the sheath. This combination forms a current lead. The current lead is attached to a cryogenic device housing a fluid coolant which moves through the current lead, cooling the current lead as the fluid travels.

  19. Ames Laboratory to lead new consortium to advance refrigeration...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Laboratory to lead new consortium to advance refrigeration technology Ames Laboratory will ... friendly and energy-efficient refrigeration technologies, sponsored by DOE's ...

  20. Johney Green to Lead NREL Mechanical and Thermal Systems Engineering...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Johney Green to Lead NREL Mechanical and Thermal Systems Engineering Research August 11, 2016 Photo of Johney Green Photo of Johney Green The Energy Department's National Renewable ...

  1. NREL Highlights Leading Utility Green Power Programs - News Releases...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NREL Highlights Leading Utility Green Power Programs March 4, 2004 Golden, Colo. - The U.S. Department of Energy's (DOE) National Renewable Energy Laboratory (NREL) today released ...

  2. NREL Ranks Leading Utility Green Power Programs - News Releases...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NREL Ranks Leading Utility Green Power Programs Pricing programs give consumers clean power choices April 3, 2007 The U.S. Department of Energy's (DOE) National Renewable Energy ...

  3. Johney Green to Lead NREL Mechanical and Thermal Systems Engineering...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Johney Green to Lead NREL Mechanical and Thermal Systems Engineering Research August 11, 2016 The Energy Department's National Renewable Energy Laboratory (NREL) has named Dr. ...

  4. Collegiate Wind Competition Rules and Regulations | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Collegiate Wind Competition Rules and Regulations Collegiate Wind Competition Rules and Regulations The competition challenges interdisciplinary teams of undergraduate students ...

  5. An Insoluble Titanium-Lead Anode for Sulfate Electrolytes

    SciTech Connect (OSTI)

    Ferdman, Alla

    2005-05-11

    The project is devoted to the development of novel insoluble anodes for copper electrowinning and electrolytic manganese dioxide (EMD) production. The anodes are made of titanium-lead composite material produced by techniques of powder metallurgy, compaction of titanium powder, sintering and subsequent lead infiltration. The titanium-lead anode combines beneficial electrochemical behavior of a lead anode with high mechanical properties and corrosion resistance of a titanium anode. In the titanium-lead anode, the titanium stabilizes the lead, preventing it from spalling, and the lead sheathes the titanium, protecting it from passivation. Interconnections between manufacturing process, structure, composition and properties of the titanium-lead composite material were investigated. The material containing 20-30 vol.% of lead had optimal combination of mechanical and electrochemical properties. Optimal process parameters to manufacture the anodes were identified. Prototypes having optimized composition and structure were produced for testing in operating conditions of copper electrowinning and EMD production. Bench-scale, mini-pilot scale and pilot scale tests were performed. The test anodes were of both a plate design and a flow-through cylindrical design. The cylindrical anodes were composed of cylinders containing titanium inner rods and fitting over titanium-lead bushings. The cylindrical design allows the electrolyte to flow through the anode, which enhances diffusion of the electrolyte reactants. The cylindrical anodes demonstrate higher mass transport capabilities and increased electrical efficiency compared to the plate anodes. Copper electrowinning represents the primary target market for the titanium-lead anode. A full-size cylindrical anode performance in copper electrowinning conditions was monitored over a year. The test anode to cathode voltage was stable in the 1.8 to 2.0 volt range. Copper cathode morphology was very smooth and uniform. There was no

  6. Litigation, Regulation and Enforcement | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Litigation, Regulation and Enforcement Litigation, Regulation and Enforcement Litigation, Regulation and Enforcement Offices of the Deputy General Counsel for Litigation, Regulation and Enforcement Office of the Assistant General Counsel for Litigation (GC-31) Office of the Assistant General Counsel for Enforcement (GC-32) Office of the Assistant General Counsel for Legislation, Regulation and Energy Efficiency (GC-33) Litigation, Regulation and Enforcement Litigation Enforcement Legislation,

  7. Electrochemical destruction of organic acids

    SciTech Connect (OSTI)

    Gendes, J.D.; Hartsough, D.; Super, J.D.

    1994-12-31

    An electrochemical process for removing organic acids from an aqueous waste stream has been characterized. Biological treatment of aqueous organic acid waste streams has been the typical means of degrading organic acids, and the resultant biosludge is landfilled. In the electrochemical approach, aqueous organic acids may be efficiently converted to useful fuel in a one or two electron process. The possible reactions occurring are outlined here. The electrolysis of the sodium salts of acetic, propionic, and butyric acids has been studied both as single component solutions and mixtures. The reaction products as well as relative rates of destruction of the acid salts were measured. The effect of experimental variables such as current density, temperature, and anode material on the current efficiency and product distribution was investigated. Electrode stability due to platinum corrosion was identified as the major limitation to the process.

  8. Street sweeping and stormwater regulations

    SciTech Connect (OSTI)

    Not Available

    1993-10-01

    This article examines the role of street sweeping in meeting the requirements of the Clean Water Act stormwater regulations. The article identifies those industrial and municipal activities which are covered by the regulations and cites frequent sweeping of site surfaces for industry and street sweeping for municipalities as an integral part of compliance plans.

  9. Fenitrothion action at the endocannabinoid system leading to spermatotoxicity in Wistar rats

    SciTech Connect (OSTI)

    Ito, Yuki; Tomizawa, Motohiro; Suzuki, Himiko; Okamura, Ai; Ohtani, Katsumi; Nunome, Mari; Noro, Yuki; Wang, Dong; Nakajima, Tamie; Kamijima, Michihiro

    2014-09-15

    Organophosphate (OP) compounds as anticholinesterase agents may secondarily act on diverse serine hydrolase targets, revealing unfavorable physiological effects including male reproductive toxicity. The present investigation proposes that fenitrothion (FNT, a major OP compound) acts on the endocannabinoid signaling system in male reproductive organs, thereby leading to spermatotoxicity (sperm deformity, underdevelopment, and reduced motility) in rats. FNT oxon (bioactive metabolite of FNT) preferentially inhibited the fatty acid amide hydrolase (FAAH), an endocannabinoid anandamide (AEA) hydrolase, in the rat cellular membrane preparation from the testis in vitro. Subsequently, male Wistar rats were treated orally with 5 or 10 mg/kg FNT for 9 weeks and the subchronic exposure unambiguously deteriorated sperm motility and morphology. The activity-based protein profiling analysis with a phosphonofluoridate fluorescent probe revealed that FAAH was selectively inhibited among the FNT-treated cellular membrane proteome in testis. Intriguingly, testicular AEA (endogenous substrate of FAAH) levels were elevated along with the FAAH inhibition caused by the subchronic exposure. More importantly, linear regression analyses for the FNT-elicited spermatotoxicity reveal a good correlation between the testicular FAAH activity and morphological indices or sperm motility. Accordingly, the present study proposes that the FNT-elicited spermatotoxicity appears to be related to inhibition of FAAH leading to overstimulation of the endocannabinoid signaling system, which plays crucial roles in spermatogenesis and sperm motility acquirement. - Highlights: • Subchronic exposure to fenitrothion induces spermatotoxicity in rats. • The fatty acid amide hydrolase is a potential target for the spermatotoxicity. • Overstimulation of the endocannabinoid signal possibly leads to the spermatotoxicity.

  10. Water supplier copes with lead paint removal regs

    SciTech Connect (OSTI)

    Becker, C.E. ); Lovejoy, D.R.; Bryck, J.L.; Rockensies, W.H.

    1993-12-01

    This article examines new paint removal methods that minimize releasing of paints containing lead to the environment and lead free coating systems for tank corrosion protection used in the Village of Freeport in Long Island, New York. The topics of the article include coating failures, removal tools and methods, paint and application methods.

  11. Method for fabricating fan-fold shielded electrical leads

    DOE Patents [OSTI]

    Rohatgi, Rajeev R.; Cowan, Thomas E.

    1994-01-01

    Fan-folded electrical leads made from copper cladded Kapton, for example, with the copper cladding on one side serving as a ground plane and the copper cladding on the other side being etched to form the leads. The Kapton is fan folded with the leads located at the bottom of the fan-folds. Electrical connections are made by partially opening the folds of the fan and soldering, for example, the connections directly to the ground plane and/or the lead. The fan folded arrangement produces a number of advantages, such as electrically shielding the leads from the environment, is totally non-magnetic, and has a very low thermal conductivity, while being easy to fabricate.

  12. Method for fabricating fan-fold shielded electrical leads

    DOE Patents [OSTI]

    Rohatgi, R.R.; Cowan, T.E.

    1994-12-27

    Fan-folded electrical leads made from copper cladded Kapton, for example, with the copper cladding on one side serving as a ground plane and the copper cladding on the other side being etched to form the leads. The Kapton is fan folded with the leads located at the bottom of the fan-folds. Electrical connections are made by partially opening the folds of the fan and soldering, for example, the connections directly to the ground plane and/or the lead. The fan folded arrangement produces a number of advantages, such as electrically shielding the leads from the environment, is totally non-magnetic, and has a very low thermal conductivity, while being easy to fabricate. 3 figures.

  13. Acidic gas capture by diamines

    DOE Patents [OSTI]

    Rochelle, Gary; Hilliard, Marcus

    2011-05-10

    Compositions and methods related to the removal of acidic gas. In particular, the present disclosure relates to a composition and method for the removal of acidic gas from a gas mixture using a solvent comprising a diamine (e.g., piperazine) and carbon dioxide. One example of a method may involve a method for removing acidic gas comprising contacting a gas mixture having an acidic gas with a solvent, wherein the solvent comprises piperazine in an amount of from about 4 to about 20 moles/kg of water, and carbon dioxide in an amount of from about 0.3 to about 0.9 moles per mole of piperazine.

  14. A new XRF method for measuring lead in paint

    SciTech Connect (OSTI)

    Grodzins, L.; Parsons, C.; Sackett, D.; Shefsky, S.; Tannian, B.

    1995-12-31

    The traditional field testing method for lead paint is the use of x-ray fluorescence, where the K shell fluorescence x-rays of lead (at 73 and 75 MeV) are measured. Although the K shell method can suffer from substrate effects and hence low sensitivity around the action level of 1 mg/cm{sup 2} of lead, it has been the industry choice because the effects of the overlying paint matrix on the K-shell x-rays are negligible. L shell x-rays of lead, at L{sub {alpha}} = 10.5 keV and L{sub {beta}} = 12.6 keV, provide much greater sensitivity and are free of substrate effects, but corrections for the absorption of the L-shell x-rays by the overlying non-lead paint matrix must be made. Such corrections were thought to be impossible without knowledge of the composition and thickness of the overlying paint matrix. NITON has developed a new method that makes it possible to use L-shell x-rays to accurately and quickly determine the absolute concentration of lead in buried lead paint (in mg/cm{sup 2}) without knowledge of the composition or thickness of the layers overlying the lead. The invention makes use of the fact that the ratio of the mass attenuation coefficients for the L{sub {alpha}} at 10.5 keV to the L{sub {beta}} at 12.6 keV is effectively independent of the elemental composition of paint layers. The new method also gives a measure of the depth of the lead beneath the surface. Theory and confirming experimental data will be presented. The authors will describe the NITON XL, a portable XRF device which uses the invention to give the lead concentration and its depth beneath the surface of paint.

  15. Research, development, and demonstration of lead-acid batteries for electric-vehicle propulsion. Annual report, 1981

    SciTech Connect (OSTI)

    1982-03-01

    The progress of the design and development program is detailed. Results of drop tests, characteristics tests, and life cycle tests are presented and discussed. Results of tests of mechanical agitation of the electrolyte by air bubbling and an air lift pump are reported. Work on the electrode designs and electrolyte circulation systems is reported. (WHK)

  16. Apparatus and methods for monitoring the concentrations of hazardous airborne substances, especially lead

    DOE Patents [OSTI]

    Zaromb, Solomon

    2004-07-13

    Air is sampled at a rate in excess of 100 L/min, preferably at 200-300 L/min, so as to collect therefrom a substantial fraction, i.e., at least 20%, preferably 60-100%, of airborne particulates. A substance of interest (analyte), such as lead, is rapidly solubilized from the the collected particulates into a sample of liquid extractant, and the concentration of the analyte in the extractant sample is determined. The high-rate air sampling and particulate collection may be effected with a high-throughput filter cartridge or with a recently developed portable high-throughput liquid-absorption air sampler. Rapid solubilization of lead is achieved by a liquid extractant comprising 0.1-1 M of acetic acid or acetate, preferably at a pH of 5 or less and preferably with inclusion of 1-10% of hydrogen peroxide. Rapid determination of the lead content in the liquid extractant may be effected with a colorimetric or an electroanalytical analyzer.

  17. Carbonic Acid Retreatment of Biomass

    SciTech Connect (OSTI)

    Baylor university

    2003-06-01

    This project sought to address six objectives, outlined below. The objectives were met through the completion of ten tasks. (1) Solidify the theoretical understanding of the binary CO{sub 2}/H{sub 2}O system at reaction temperatures and pressures. The thermodynamics of pH prediction have been improved to include a more rigorous treatment of non-ideal gas phases. However it was found that experimental attempts to confirm theoretical pH predictions were still off by a factor of about 1.8 pH units. Arrhenius experiments were carried out and the activation energy for carbonic acid appears to be substantially similar to sulfuric acid. Titration experiments have not yet confirmed or quantified the buffering or acid suppression effects of carbonic acid on biomass. (2) Modify the carbonic acid pretreatment severity function to include the effect of endogenous acid formation and carbonate buffering, if necessary. It was found that the existing severity functions serve adequately to account for endogenous acid production and carbonate effects. (3) Quantify the production of soluble carbohydrates at different reaction conditions and severity. Results show that carbonic acid has little effect on increasing soluble carbohydrate concentrations for pretreated aspen wood, compared to pretreatment with water alone. This appears to be connected to the release of endogenous acids by the substrate. A less acidic substrate such as corn stover would derive benefit from the use of carbonic acid. (4) Quantify the production of microbial inhibitors at selected reaction conditions and severity. It was found that the release of inhibitors was correlated to reaction severity and that carbonic acid did not appear to increase or decrease inhibition compared to pretreatment with water alone. (5) Assess the reactivity to enzymatic hydrolysis of material pretreated at selected reaction conditions and severity. Enzymatic hydrolysis rates increased with severity, but no advantage was detected for

  18. Carbonic Acid Pretreatment of Biomass

    SciTech Connect (OSTI)

    G. Peter van Walsum; Kemantha Jayawardhana; Damon Yourchisin; Robert McWilliams; Vanessa Castleberry

    2003-05-31

    This project sought to address six objectives, outlined below. The objectives were met through the completion of ten tasks. 1) Solidify the theoretical understanding of the binary CO2/H2O system at reaction temperatures and pressures. The thermodynamics of pH prediction have been improved to include a more rigorous treatment of non-ideal gas phases. However it was found that experimental attempts to confirm theoretical pH predictions were still off by a factor of about 1.8 pH units. Arrhenius experiments were carried out and the activation energy for carbonic acid appears to be substantially similar to sulfuric acid. Titration experiments have not yet confirmed or quantified the buffering or acid suppression effects of carbonic acid on biomass. 2) Modify the carbonic acid pretreatment severity function to include the effect of endogenous acid formation and carbonate buffering, if necessary. It was found that the existing severity functions serve adequately to account for endogenous acid production and carbonate effects. 3) Quantify the production of soluble carbohydrates at different reaction conditions and severity. Results show that carbonic acid has little effect on increasing soluble carbohydrate concentrations for pretreated aspen wood, compared to pretreatment with water alone. This appears to be connected to the release of endogenous acids by the substrate. A less acidic substrate such as corn stover would derive benefit from the use of carbonic acid. 4) Quantify the production of microbial inhibitors at selected reaction conditions and severity. It was found that the release of inhibitors was correlated to reaction severity and that carbonic acid did not appear to increase or decrease inhibition compared to pretreatment with water alone. 5) Assess the reactivity to enzymatic hydrolysis of material pretreated at selected reaction conditions and severity. Enzymatic hydrolysis rates increased with severity, but no advantage was detected for the use of carbonic

  19. Numerical Model for Conduction-Cooled Current Lead Heat Loads

    SciTech Connect (OSTI)

    White, M.J.; Wang, X.L.; Brueck, H.D.; /DESY

    2011-06-10

    Current leads are utilized to deliver electrical power from a room temperature junction mounted on the vacuum vessel to a superconducting magnet located within the vacuum space of a cryostat. There are many types of current leads used at laboratories throughout the world; however, conduction-cooled current leads are often chosen for their simplicity and reliability. Conduction-cooled leads have the advantage of using common materials, have no superconducting/normal state transition, and have no boil-off vapor to collect. This paper presents a numerical model for conduction-cooled current lead heat loads. This model takes into account varying material and fluid thermal properties, varying thicknesses along the length of the lead, heat transfer in the circumferential and longitudinal directions, electrical power dissipation, and the effect of thermal intercepts. The model is validated by comparing the numerical model results to ideal cases where analytical equations are valid. In addition, the XFEL (X-Ray Free Electron Laser) prototype current leads are modeled and compared to the experimental results from testing at DESY's XFEL Magnet Test Stand (XMTS) and Cryomodule Test Bench (CMTB).

  20. Zinc halogen battery electrolyte composition with lead additive

    DOE Patents [OSTI]

    Henriksen, Gary L.

    1981-01-01

    This disclosure relates to a zinc halogen battery electrolyte composition containing an additive providing improved zinc-on-zinc recyclability. The improved electrolyte composition involves the use of a lead additive to inhibit undesirable irregular plating and reduce nodular or dendritic growth on the electrode surface. The lead-containing electrolyte composition of the present invention appears to influence not only the morphology of the base plate zinc, but also the morphology of the zinc-on-zinc replate. In addition, such lead-containing electrolyte compositions appear to reduce hydrogen formation.

  1. Department of Energy Recognizes Six Leading Organizations for Helping the

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    U.S. 'Go Green' | Department of Energy Six Leading Organizations for Helping the U.S. 'Go Green' Department of Energy Recognizes Six Leading Organizations for Helping the U.S. 'Go Green' October 22, 2007 - 3:21pm Addthis 2007 National Green Power Supplier Award Winners WASHINGTON, DC - The U.S. Department of Energy (DOE) will recognize six leading organizations at the Seventh Annual Green Power Leadership Awards tonight in Philadelphia for advancing the development and use of "green

  2. Alternative Fuels Data Center: Conversion Regulations

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    Conversion Regulations to someone by E-mail Share Alternative Fuels Data Center: Conversion Regulations on Facebook Tweet about Alternative Fuels Data Center: Conversion Regulations on Twitter Bookmark Alternative Fuels Data Center: Conversion Regulations on Google Bookmark Alternative Fuels Data Center: Conversion Regulations on Delicious Rank Alternative Fuels Data Center: Conversion Regulations on Digg Find More places to share Alternative Fuels Data Center: Conversion Regulations on

  3. APPARATUS FOR REGULATING HIGH VOLTAGE

    DOE Patents [OSTI]

    Morrison, K.G.

    1951-03-20

    This patent describes a high-voltage regulator of the r-f type wherein the modulation of the r-f voltage is accomplished at a high level, resulting in good stabilization over a large range of load conditions.

  4. Environmental Regulations | Open Energy Information

    Open Energy Info (EERE)

    Regulations Jump to: navigation, search To do: add table This article is a stub. You can help OpenEI by expanding it. Retrieved from "http:en.openei.orgwindex.php?titleEnviron...

  5. President Obama to Honor Nation's Leading Scientists and Innovators...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    President Obama to Honor Nation's Leading Scientists and Innovators January 22, 2016 - 10:59am Addthis Original content from Whitehouse.gov The White House announced the latest ...

  6. NATIONAL LEAD COMPANY OF OHIO HEALTH AND SAFETY DIVISION - ANALYTICAL...

    Office of Legacy Management (LM)

    J &' fi -35-24 saps RUSH NATIONAL LEAD COMPANY OF OHIO HEALTH AND SAFETY DIVISION - ANALYTICAL DEPT. ANALYTICAL DATA SHEET ULO-n&s-736 (REV. 8u591 -----" . . . , -.-.-- ....

  7. Leading Edge Erosion Phase II Wind Tunnel Test Begins

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... Wind tunnel testing is commencing for the second phase of the leading edge erosion project, which is a collaboration between Texas A&M, UC Davis, and Sandia. During the 2012 fiscal ...

  8. Method and apparatus for diagnosis of lead toxicity

    DOE Patents [OSTI]

    Rosen, John F.; Slatkin, Daniel N.; Wielopolski, Lucian

    1989-01-01

    Improved methods and apparatus for in vivo measurement of the skeletal lead burden of a patient and for diagnosis of lead toxicity are disclosed. The apparatus comprises an x-ray tube emitting soft low energy x-rays from a silver anode, a polarizer for polarizing the emitted x-rays, and a detector for detecting photons fluoresced from atoms in the patient's tibia upon irradiation by the polarized x-rays. The fluoresced photons are spectrally analyzed to determine their energy distribution. Peaks indicating the presence of lead are identified if the patient has relatively high bone lead content. The data may be compared to data recorded with respect to a similar test performed on patients having also had the conventional EDTA chelation tests performed thereon in order to correlate the test results with respect to a particular patient to the conventionally accepted EDTA chelation test.

  9. Lab Discovery: Water Leads to Chemical that "Gunks Up" Biofuels...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Lab Discovery: Water Leads to Chemical that "Gunks Up" Biofuels Production November 20, 2014 - 12:16pm Addthis In this episode of 90 Seconds of Discovery, Catalysis Scientist ...

  10. Leading the Charge: Jana Ganion Advances Blue Lake Rancheria...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... We just received initial Notice of Proposed Award for a 500-kW ground-mounted solar array with a grid storage battery system, controlled with leading-edge microgrid technology. If ...

  11. Eliot Feibush leads new Princeton consortium to visualize Big...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Eliot Feibush leads new Princeton consortium to visualize Big Data By John Greenwald April 22, 2015 Tweet Widget Google Plus One Share on Facebook Eliot Feibush (Photo by Elle ...

  12. Eliot Feibush leads new Princeton consortium to visualize Big...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Eliot Feibush leads new Princeton consortium to visualize Big Data By John Greenwald April 20, 2015 Tweet Widget Google Plus One Share on Facebook Eliot Feibush (Photo by Elle ...

  13. Researchers Achieve Breakthrough in Solving Leading Cause of Gearbox Failures

    Broader source: Energy.gov [DOE]

    Accomplishing a significant milestone, researchers from the U.S. Department of Energy’s Argonne National Laboratory have successfully replicated the leading cause of wind turbine gearbox failures,...

  14. The Source of Airborne Lead: Recycling Pb-Contaminated Soils

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    correspondingly 2,3. Despite this dramatic improvement in both exposure risk and body burden of Pb, the sources and health threat of the low levels of lead in our...

  15. Department of Energy Recognizes Six Leading Organizations for...

    Energy Savers [EERE]

    October 22, 2007 - 3:21pm Addthis 2007 National Green Power Supplier Award Winners WASHINGTON, DC - The U.S. Department of Energy (DOE) will recognize six leading organizations at ...

  16. Interference with BRCA2, which localizes to the centrosome during S and early M phase, leads to abnormal nuclear division

    SciTech Connect (OSTI)

    Nakanishi, Akira; Han, Xiangzi; Saito, Hiroko; Taguchi, Keiko; Ohta, Yoshiyasu; Imajoh-Ohmi, Shinobu; Miki, Yoshio; E-mail: miki.mgen@mri.tmd.ac.jp

    2007-03-30

    BRCA2 is responsible for familial breast and ovarian cancer, and its gene product is linked to DNA repair and transcriptional regulation. The BRCA2 protein exists mainly in the nucleus. Here, we show that BRCA2 has a centrosomal localization signal (CLS), localizes also to centrosomes during S and early M phases, and may regulate duplication and separation of the centrosomes. Green fluorescent protein (GFP) fused to the CLS peptides from BRCA2 (GFP-CLS) localizes to centrosomes and prevents endogenous BRCA2 from localizing to centrosomes. In addition, expression of GFP-CLS in cells leads to the abnormal duplication and positioning of centrosomes, resulting in the generation of multinuclear cells. These results thus implicate BRCA2 in the regulation of the centrosome cycle, and provide new insight into the aneuploid nature of many breast cancers.

  17. Updating about reductions of air and blood lead concentrations in Turin, Italy, following reductions in the lead content of gasoline

    SciTech Connect (OSTI)

    Bono, R.; Pignata, C.; Gilli, G.

    1995-07-01

    Considering its well known toxicity and the chronic human exposure to lead, international lawmakers enforced some directives or laws calling for the reduction of lead content in gasoline. All of these legislative acts aimed to reduce health risks for the general population. The aim of this study was to consider the effectiveness of these laws on air lead levels and consequently on blood lead levels in a randomly selected urban Italian population. In particular, these markers were analyzed over the course of several years, corresponding to the periods just before and after enforcements of the reductions of lead in petrol. Data presented point out some considerations: (1) enforcement of legislative measures concerning the reduction of lead in petrol has reduced atmospheric levels of lead. This result demonstrates a major environmental success in primary prevention efforts. (2) This success is clear especially considering that the actual Pb-B levels can be extended to the urbanized populations. Pb-B levels were consistently higher for drinkers, for older adults and for males. The mean of Pb-B level for the present urbanized population is higher than the U.S. overall population (6.4 vs 3 {mu}g/dl). This difference can be also explained considering the different historical period of enforcement of the restriction laws. 10 refs., 3 figs., 3 tabs.

  18. Unique Auxin Regulation Mechanism Discovered

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Unique Auxin Regulation Mechanism Discovered Print The plant hormone auxin regulates many plant growth and development processes, including shoot growth, root branching, fruit ripening, tropisms, and flowering. But how such a simple molecule elicits such a variety of cellular responses has been a mystery. An important breakthrough came in 2005, wh en a conserved plant protein known as TIR1 (part of a protein destruction machinery system) was identified as a receptor for auxin. Now, an

  19. Unique Auxin Regulation Mechanism Discovered

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Unique Auxin Regulation Mechanism Discovered Print The plant hormone auxin regulates many plant growth and development processes, including shoot growth, root branching, fruit ripening, tropisms, and flowering. But how such a simple molecule elicits such a variety of cellular responses has been a mystery. An important breakthrough came in 2005, wh en a conserved plant protein known as TIR1 (part of a protein destruction machinery system) was identified as a receptor for auxin. Now, an

  20. Unique Auxin Regulation Mechanism Discovered

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Unique Auxin Regulation Mechanism Discovered Print The plant hormone auxin regulates many plant growth and development processes, including shoot growth, root branching, fruit ripening, tropisms, and flowering. But how such a simple molecule elicits such a variety of cellular responses has been a mystery. An important breakthrough came in 2005, wh en a conserved plant protein known as TIR1 (part of a protein destruction machinery system) was identified as a receptor for auxin. Now, an

  1. Unique Auxin Regulation Mechanism Discovered

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Unique Auxin Regulation Mechanism Discovered Print The plant hormone auxin regulates many plant growth and development processes, including shoot growth, root branching, fruit ripening, tropisms, and flowering. But how such a simple molecule elicits such a variety of cellular responses has been a mystery. An important breakthrough came in 2005, wh en a conserved plant protein known as TIR1 (part of a protein destruction machinery system) was identified as a receptor for auxin. Now, an

  2. Federal Regulations | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Federal Regulations Federal Regulations NOTE: Adobe Acrobat Reader may be necessary to view PDF documents listed below. Accessibility Section 508 of the Rehabilitation Act - Electronic and Information Technology Accessibility Standards Section 504 of the Rehabilitation Act - Nondiscrimination Under Federal Grants and Programs Federal Records Act Freedom of Information Act (as amended) Freedom of Information Act Updates Privacy Act of 1974 (as amended) Privacy Act Overview Cyber Security Atomic

  3. Volunteers Leading Technology, A Case Study: Chewonki Renewable Hydrogen

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Project | Department of Energy Volunteers Leading Technology, A Case Study: Chewonki Renewable Hydrogen Project Volunteers Leading Technology, A Case Study: Chewonki Renewable Hydrogen Project This presentation by Paul Faulstich focuses on the Chewonki Renewable Hydrogen Project. education_presentation_faulstich.pdf (586.19 KB) More Documents & Publications EIS-0073: Final Environmental Impact Statement EIS-0063: Final Environmental Impact Statement EIS-0063: Draft Environmental Impact

  4. DOE-Idaho Leads Regional Combined Federal Campaign

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    DOE NEWS RELEASE DOE-Idaho Leads Regional Combined Federal Campaign FOR IMMEDIATE RELEASE December 5, 2007 Media Contact: Brad Bugger, (208) 526-8484 The U.S. Department of Energy's Idaho Operations Office is once again leading the regional Combined Federal Campaign, which is the only sanctioned charitable campaign for all federal employees. Idaho Operations Office staff evaluates applications from local non-profit organizations who want to be included in the Combined Federal Campaign, to make

  5. WIPP's Mine Rescue Teams Lead Competition | Department of Energy

    Office of Environmental Management (EM)

    WIPP's Mine Rescue Teams Lead Competition WIPP's Mine Rescue Teams Lead Competition July 30, 2013 - 12:00pm Addthis WIPP’s mine rescue team members, back row from left, are NWP President and Project Manager Farok Sharif; Heath Fowler; Manny Marquez; Mat Ridgway; Gary Kessler; Curtis Sanders, III; Jim Pierce; Tony Mihelic; Joe Baca; Justin Bailey; Ty Zimmerly; Fabian Carrasco; Chauncey Ortega; Nico Dominguez; and CBFO Manager Joe Franco. In front are Richard West, team trainer; and Ann

  6. Lead-free Thin Film Piezoelectric Devices - Energy Innovation Portal

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Vehicles and Fuels Vehicles and Fuels Find More Like This Return to Search Lead-free Thin Film Piezoelectric Devices Lawrence Berkeley National Laboratory Contact LBL About This Technology Technology Marketing SummaryIn a breakthrough discovery, Ramamoorthy Ramesh, Robert Zeches, and their research team at Berkeley Lab have developed a technology for lead-free piezoelectric materials using thin-film bismuth ferrite. In addition to being less hazardous to human health and the environment, the

  7. Secretaries Chu and Salazar Lead Administration Team Offering Federal

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Scientific and Technological Support to BP Engineers | Department of Energy Lead Administration Team Offering Federal Scientific and Technological Support to BP Engineers Secretaries Chu and Salazar Lead Administration Team Offering Federal Scientific and Technological Support to BP Engineers May 12, 2010 - 12:00am Addthis HOUSTON, TX -- At the request of the President, Secretary Chu and Secretary Salazar traveled to Houston today to participate in meetings with DOE and national lab staff,

  8. Richard Gerber Named New NERSC User Services Group Lead

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Richard Gerber New NERSC User Services Group Lead Richard Gerber Named New NERSC User Services Group Lead December 12, 2013 RichardGerber.jpg Richard Gerber Richard Gerber has been named leader of the NERSC User Services Group (USG), effective immediately. He takes over for Katie Antypas, who was appointed head of the NERSC Services Department in September. In his new role, Gerber will be responsible for managing a group that works to increase the scientific productivity of NERSC's 4,700 users.

  9. Weerts to lead Physical Sciences and Engineering directorate | Argonne

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    National Laboratory Weerts to lead Physical Sciences and Engineering directorate By Lynn Tefft Hoff * August 10, 2015 Tweet EmailPrint Hendrik (Harry) Joseph Weerts has been named the associate laboratory director for the Physical Sciences and Engineering (PSE) directorate at the U.S. Department of Energy's Argonne National Laboratory. Weerts has served in the role on an interim basis since May 2014. As part of Argonne's senior management team, Weerts will lead the PSE directorate and its

  10. Solar Decathlon 2015: Nation's Leading Sustainable Home Design

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Competition on the Horizon | Department of Energy Decathlon 2015: Nation's Leading Sustainable Home Design Competition on the Horizon Solar Decathlon 2015: Nation's Leading Sustainable Home Design Competition on the Horizon July 13, 2015 - 2:15pm Addthis The New York City College of Technology is weatherproofing its house, called DURA, at a Brooklyn Navy Yard construction site. | Photo courtesy of New York City College of Technology. The New York City College of Technology is weatherproofing

  11. EM Selects Ralph Holland to Lead Consolidated Business Center | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of Energy Selects Ralph Holland to Lead Consolidated Business Center EM Selects Ralph Holland to Lead Consolidated Business Center August 10, 2015 - 2:00pm Addthis Ralph Holland, Environmental Management Consolidated Business Center Ralph Holland, Environmental Management Consolidated Business Center WASHINGTON, D.C. - EM has named Ralph Holland director of the Environmental Management Consolidated Business Center (EMCBC) in Cincinnati. Holland has served in various contracting, supervisory,

  12. Energy recovery experiment could lead way to new accelerators | Jefferson

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Lab recovery experiment could lead way to new accelerators One of four BE magnets Corey Butler, mechanical designer; (left to right) Alex Bogacz, CASA staff scientist and experiment co-spokesman; and Robby Hicks, mechanical engineer, stand with one of the four BE magnets and a section of vacuum chamber built by the Machine Shop specifically for the Energy Recovery experiment. Energy recovery experiment could lead way to new accelerators March 6, 2003 Jefferson Lab physicists will soon begin

  13. President Obama to Honor Nation's Leading Scientists and Innovators |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy President Obama to Honor Nation's Leading Scientists and Innovators President Obama to Honor Nation's Leading Scientists and Innovators January 22, 2016 - 10:59am Addthis Original content from Whitehouse.gov The White House announced the latest recipients of the National Medal of Science and National Medal of Technology and Innovation-our Nation's highest honors for achievement and leadership in advancing the fields of science and technology. The new awardees will

  14. Institute for Advanced Composites Helping America Lead on Clean Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Manufacturing | Department of Energy Institute for Advanced Composites Helping America Lead on Clean Energy Manufacturing Institute for Advanced Composites Helping America Lead on Clean Energy Manufacturing June 18, 2015 - 4:28pm Addthis Assistant Secretary for Energy Efficiency and Renewable Energy Dr. David Danielson speaks during the launch of the Institute for Advanced Composites Manufacturing Innovation in Knoxville, Tennessee. | Photo courtesy of Oak Ridge National Laboratory.

  15. Inspiration from world-class scientists leads Patricia Langan to

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    nanoscience Inspiration from world-class scientists leads student to nanoscience Inspiration from world-class scientists leads Patricia Langan to nanoscience Graduate research assistant discovered her passion while interning as an undergraduate student in the Bioscience Division. August 1, 2012 Patricia Langan Patricia Langan has been a student for five years now. After graduating with a B.S in Molecular, Cell and Developmental Biology from the University of California, Santa Cruz, she

  16. 2016 Leading Rater Round Table Report | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Leading Rater Round Table Report 2016 Leading Rater Round Table Report A dramatic movement to zero energy ready homes is just beginning. This includes statewide codes, large developments, and a growing commitment to the DOE Zero Energy Ready Home program. Continued progress will rely on an increasing number of Home Energy Rating System (HERS) raters effectively bringing the business case, technical solutions, and verification services for Zero Energy Ready Home to our nation's builders. At this

  17. A Minority Serving Institution Leads the Way in Better Buildings |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy A Minority Serving Institution Leads the Way in Better Buildings A Minority Serving Institution Leads the Way in Better Buildings July 5, 2012 - 6:06pm Addthis Secretary Chu visits Delaware State University to commemorate the school's efforts with the Better Buildings Initiative. Secretary Chu visits Delaware State University to commemorate the school's efforts with the Better Buildings Initiative. Dot Harris Dot Harris Director, Office of Economic Impact and Diversity

  18. Questions about how plants die leads to climate change answers

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Questions about how plants die leads to climate change answers Questions about how plants die leads to climate change answers Understanding mechanisms of mortality will provide important input to future climate forecasts. March 12, 2012 Tree in the desert The scientists' goal is to provide basic insights into questions such as how plants die, especially during drought. While the question of plant mortality is easy to conceptualize, it is difficult to study because of the spatial and temporal

  19. United States Regains Lead with World's Fastest Supercomputer |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Regains Lead with World's Fastest Supercomputer United States Regains Lead with World's Fastest Supercomputer June 18, 2012 - 2:02pm Addthis NEWS MEDIA CONTACT (202) 586-4940 WASHINGTON - Energy Secretary Steven Chu today announced that a supercomputer called Sequoia at Lawrence Livermore National Laboratory (LLNL) in Livermore, California, received the rank of the world's most powerful computing system. The Top500 list, which annually ranks the world's fastest

  20. Lead Research and Development Activity for High Temperature, Low Relative

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Humidity Membrane Program | Department of Energy Lead Research and Development Activity for High Temperature, Low Relative Humidity Membrane Program Lead Research and Development Activity for High Temperature, Low Relative Humidity Membrane Program A presentation to the High Temperature Membranes Working Group meeting, May 19, 2006. fenton.pdf (448.4 KB) More Documents & Publications Discussion Overview In Plane Conductivity Testing, BekkTech LLC Progress and Status on Through-Plane

  1. Leading Edge Technology in Diesel Emissions Control | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Leading Edge Technology in Diesel Emissions Control Leading Edge Technology in Diesel Emissions Control Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010. p-02_roberts.pdf (193.56 KB) More Documents & Publications NO2 Management in Diesel Exhaust System Experimental Evaluation of DOC Performance Using Secondary Fuel Injection Low Temperature Catalyst for Fuel Injection System

  2. Leading the Charge: Chairman Vig Champions Progress, Sustainability |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Chairman Vig Champions Progress, Sustainability Leading the Charge: Chairman Vig Champions Progress, Sustainability October 20, 2014 - 5:00pm Addthis A photo of Chairman Vig. Change doesn't happen on its own. It's led by dedicated and passionate people who are committed to empowering Indian Country to energize future generations. Leading the Charge is a regular feature spotlighting the movers and shakers in energy on tribal lands. This issue we had the opportunity to

  3. Leading the Nation in Clean Energy Deployment | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Leading the Nation in Clean Energy Deployment Leading the Nation in Clean Energy Deployment This document summarizes key efforts and projects that are part of the DOE/NREL Integrated Deployment effort to integrated energy efficiency and renewable energy technologies in cities, states, island locations, and communities around the world. id_overview.pdf (569.07 KB) More Documents & Publications A Tale of Two Cities: Greensburg Rebuilds as a National Model for Green Communities (Fact Sheet)

  4. Imagine Tomorrow: Student Competition Leads to Innovative Biofuel Ideas |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Imagine Tomorrow: Student Competition Leads to Innovative Biofuel Ideas Imagine Tomorrow: Student Competition Leads to Innovative Biofuel Ideas May 28, 2014 - 9:20am Addthis Watch the video above to learn more about the Imagine Tomorrow competition. Leslie Ovard Bioenergy Policy Specialist, Bioenergy Technologies Office Can you imagine if solar panels could be used to grow algae for fuel? Or if your morning coffee could not only get your day started, but also serve as a

  5. Lab Breakthrough: Fusion Research Leads to Antiterrorism Device |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Fusion Research Leads to Antiterrorism Device Lab Breakthrough: Fusion Research Leads to Antiterrorism Device June 26, 2012 - 12:17pm Addthis Researchers at the Princeton Plasma Physics Laboratory developed an antiterrorism device that can detect and identify sources of dangerous radiation that could be used in a dirty bomb. See the other Lab Breakthrough videos on the YouTube playlist. Michael Hess Michael Hess Former Digital Communications Specialist, Office of Public

  6. Cooperative Catalyst leads to Transformative Results | The Ames Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Cooperative Catalyst leads to Transformative Results Capitalizing on the concept that everything proceeds faster with a little cooperation, researchers showed how designing cooperation into solid catalysts leads to enormous benefits.Catalysts attached to a porous solid support are preferred industrially because they are easier to separate from liquid products and reuse. But, these bound catalysts typically do not perform as well and probing their interiors to figure out how to improve them has

  7. Glass composition development for stabilization of lead based paints

    SciTech Connect (OSTI)

    Marra, J.C.

    1996-10-01

    Exposure to lead can lead to adverse health affects including permanent damage to the central nervous system. Common means of exposure to lead are from ingestion of lead paint chips or breathing of dust from deteriorating painted surfaces. The U.S. Army has over 101 million square feet of buildings dating to World War II or earlier. Many of these structures were built before the 1978 ban on lead based paints. The U.S. Army Corps of Engineers CERL is developing technologies to remove and stabilize lead containing organic coatings. Promising results have been achieved using a patented flame spray process that utilizes a glass frit to stabilize the hazardous constituents. When the glass frit is sprayed onto the paint containing substrate, differences in thermal expansion coefficients between the frit and the paint results in spalling of the paint from the substrate surface. The removed fragments are then collected and remelted to stabilize the hazardous constituents and allow for disposal as non-hazardous waste. Similar successful results using a patented process involving microwave technology for paint removal have also been achieved. In this process, the painted surface is coated with a microwave coupling compound that when exposed to microwave energy results in the spalling of the hazardous paint from the surface. The fragments can again be accumulated and remelted for stabilization and disposal.

  8. MERCURY AND LEAD SAMPLING AT MINNESOTA POWER'S BOSWELL ENERGY CENTER

    SciTech Connect (OSTI)

    Dennis L. Laudal

    2000-08-01

    At the request of the Minnesota Power, Inc., the Energy & Environmental Research Center (EERC) sampled for lead at the stack (or duct directly leading to the stack) for three units at the Boswell Energy Center. All sampling was done in triplicate using U.S. Environmental Protection Agency (EPA) Method 12, with sampling procedures following EPA Methods 1 through 4. During the test program, lead sampling was done using EPA Method 12 in the duct at the outlet of the baghouse serving Unit 2 and the duct at the outlet of the wet particulate scrubber serving Unit 3. For Unit 4, lead sampling was done at the stack. The specific objective for the project was to determine the concentration of lead in the flue gas being emitted into the atmosphere from the Boswell Energy Center. The test program was performed during the period of May 8 through 11, 2000. This report presents the test data, sample calculations, and results, and a discussion of the lead sampling performed at the Boswell Energy Center. The detailed test data and test results, raw test data, process data, laboratory reports, and equipment calibration records are provided in Appendices A, B, and C.

  9. Vitrification of lead-based paint using thermal spray

    SciTech Connect (OSTI)

    Kumar, A.; Covey, S.W.; Lattimore, J.L.; Boy, J.H.

    1996-12-31

    Lead-based paint (LBP) primers have been used to protect steel structures from corrosion. Abrasive blasting is currently used to remove old LBP. During abrasive blasting a containment structure is required to keep the hazardous lead dust from contaminating air, soil, or water. A thermal spray vitrification (TSV) process to remove LBP was developed. Dried glass powder is melted in the high temperature flame of the thermal spray torch. When the glass strikes the substrate it is molten and reacts with the paint on the substrate. The organic components of the paint are pyrolyzed, while the lead ions are trapped on the surface of glass. The quenching stresses in the glass cause the glass to crack and spall off the substrate. The crumbled glass fragments can be collected and remelted, immobilizing the lead ions within the glass network, thereby preventing leaching. The resulting glass can be disposed of as non-hazardous waste. The process is dust-free, eliminating the need for containment. The volume of residue waste is less than for abrasive blasting and is nonhazardous. The concept and techniques of using the thermal spray vitrification process for the removal and the containment of lead from a section of a bridge containing lead-based paint have been successfully demonstrated.

  10. Lead in human blood from children living in Campania, Italy

    SciTech Connect (OSTI)

    Amodio-Cocchieri, R.; Arnese, A.; Prospero, E.; Roncioni, A.

    1996-03-01

    Blood lead (PbB) levels were determined in children living Campania (in Naples and in a rural zone in the district of Caserta). Atmospheric lead (PbA) concentration in these considered areas was monitored for 1 yr (1993-1994). The children tested were questioned about common sources of lead, other than atmospheric relating to their living and dietary habits. The PbB levels in children living in Naples were at the 50th percentile, 18.8 {mu}g/dl in males and 13.7 {mu}g/dl in females; in children living in the rural area the median PbB levels were 8.9{mu}g/dl in males, and 9.9 {mu}g/dl in females. The annual mean values of atmospheres lead were 1.15 {plus_minus} 0.24 {mu}g/dl in Naples and 0.23 {plus_minus} 0.07 {mu}g/dl in the rural area. Significant and congruent mean differences between urban and rural sites were found in children`s blood and concurrent air lead. Considering the PbB level of 10 {mu}g/dl as the maximum level that is not associated any known adverse effect in children, the Neapolitan group can be considered at risk of chronic intoxication by lead. 18 refs., 3 figs., 4 tabs.

  11. Prediction of epigenetically regulated genes in breast cancer cell lines

    SciTech Connect (OSTI)

    Loss, Leandro A; Sadanandam, Anguraj; Durinck, Steffen; Nautiyal, Shivani; Flaucher, Diane; Carlton, Victoria EH; Moorhead, Martin; Lu, Yontao; Gray, Joe W; Faham, Malek; Spellman, Paul; Parvin, Bahram

    2010-05-04

    Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation of CpG islands may silence associated genes. Therefore, using high-throughput microarrays to measure CpG island methylation will lead to better understanding of tumor pathobiology and progression, while revealing potentially new biomarkers. We have examined a recently developed high-throughput technology for measuring genome-wide methylation patterns called mTACL. Here, we propose a computational pipeline for integrating gene expression and CpG island methylation profles to identify epigenetically regulated genes for a panel of 45 breast cancer cell lines, which is widely used in the Integrative Cancer Biology Program (ICBP). The pipeline (i) reduces the dimensionality of the methylation data, (ii) associates the reduced methylation data with gene expression data, and (iii) ranks methylation-expression associations according to their epigenetic regulation. Dimensionality reduction is performed in two steps: (i) methylation sites are grouped across the genome to identify regions of interest, and (ii) methylation profles are clustered within each region. Associations between the clustered methylation and the gene expression data sets generate candidate matches within a fxed neighborhood around each gene. Finally, the methylation-expression associations are ranked through a logistic regression, and their significance is quantified through permutation analysis. Our two-step dimensionality reduction compressed 90% of the original data, reducing 137,688 methylation sites to 14,505 clusters. Methylation-expression associations produced 18,312 correspondences, which were used to further analyze epigenetic regulation. Logistic regression was used to identify 58 genes from these correspondences that showed a statistically signifcant negative correlation between methylation profles and gene expression in the

  12. Comparison of silatrane, phosphonic acid, and carboxylic acid...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    cells Authors: Brennan, B.J., Llansola Portoles, M.J., Liddell, P.A., Moore, T.A., Moore, A.L., and Gust, D. Title: Comparison of silatrane, phosphonic acid, and...

  13. Oxygen-­dependent regulation of bacterial lipid production

    SciTech Connect (OSTI)

    Lemmer, Kimberly C.; Dohnalkova, Alice C.; Noguera, Daniel R.; Donohue, Timothy J.

    2015-05-02

    Understanding the mechanisms of lipid accumulation in microorganisms is important for several reasons. In addition to providing insight into assembly of biological membranes, lipid accumulation has important applications in the production of renewable fuels and chemicals. The photosynthetic bacterium Rhodobacter sphaeroides is an attractive organism to study lipid accumulation, as it has the somewhat unique ability to increase membrane production at low O₂ tensions. Under these conditions, R. sphaeroides develops invaginations of the cytoplasmic membrane to increase its membrane surface area for housing of the membrane-bound components of its photosynthetic apparatus. Here we use fatty acid levels as a reporter of membrane lipid content. We show that, under low-O₂ and anaerobic conditions, the total fatty acid content per cell increases 3-fold. We also find that the increases in the amount of fatty acid and photosynthetic pigment per cell are correlated as O₂ tensions or light intensity are changed. To ask if lipid and pigment accumulation were genetically separable, we analyzed strains with mutations in known photosynthetic regulatory pathways. While a strain lacking AppA failed to induce photosynthetic pigment-protein complex accumulation, it increased fatty acid content under low O2 conditions. We also found that an intact PrrBA pathway is required for low O2-induced fatty acid accumulation. In conclusion, our findings suggest a previously unknown role of R. sphaeroides transcriptional regulators in increasing fatty acid and phospholipid accumulation in response to decreased O₂ tension.

  14. Energy-conserving, pollution-free extraction process for the recovery of lead from lead sulfide concentrates. Final report

    SciTech Connect (OSTI)

    Rao, Y.K.

    1981-09-01

    Research concerned with the development of a new process for the extraction of lead from lead sulfide concentrates is described. The process consists of smelting lead sulfide concentrates with lime and carbon to produce liquid lead. The sulfur in the concentrates is tied up as solid calcium sulfide residue which can be further processed to regenerate lime. No sulfur oxides are generated during the process. The off-gases consist of CO and CO/sub 2/. Coke, coal, coal-char or lignite-char may be used as reducing agents. The reduction process can be catalyzed to an appreciable degree by the addition of small concentrations of catalysts. For the most part, these catalytic substances are either pure or mixed alkali-metal salts. The present process can be applied for extracting zinc from zinc sulfide concentrates and also for the recovery of copper and nickel from their respective sulfide concentrates.

  15. Energy-conserving, pollution-free extraction process for the recovery of lead from lead sulfide concentrates. Final report

    SciTech Connect (OSTI)

    Rao, Y.K.

    1981-09-01

    Research concerned with the development of a new process for the extraction of lead from lead sulfide concentrates is described. The process consists of smelting lead sulfide concentrates with lime and carbon to produce liquid lead. The sulfur in the concentrates is tied up as solid calcium sulfide residue which can be further processed to regenerate lime. No sulfur oxides are generated during the process. The off-gas consist of CO and CO/sub 2/. Coke, coal, coal-char or lignite-char may be used as reducing agents. The reduction process can be catalyzed to an appreciable degree by the addition of small concentrations of catalysts. For the most part, these catalytic substances are either pure or mixed alkali-metal salts. The present process can be applied for extracting zinc from zinc sulfide concentrates and also for the recovery of copper and nickel from their respective sulfide concentrates.

  16. PRODUCTION OF TRIFLUOROACETIC ACID COMPOUNDS

    DOE Patents [OSTI]

    Haworth, W.N.; Stacey, M.

    1949-08-30

    A process is described for the preparation of trifluoroacetic acid. Acetone vapor diluted wlth nitrogen and fluorine also diluted with nltrogen are fed separately at a temperature of about 210 deg C into a reaction vessel containing a catalyst mass selected from-the group consisting of silver and gold. The temperature in the reaction vessel is maintained in the range of 200 deg to 250 deg C. The reaction product, trifluoroacetyl fluoride, is absorbed in aqueous alkali solution. Trifluoroacetic acid is recovered from the solution by acidification wlth an acid such as sulfuric followed by steam distillation.

  17. Better Buildings Residential Network Peer Exchange Call Series: Generating Energy Efficiency Project Leads and Allocating Leads to Contractors

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Generating Energy Efficiency Project Leads and Allocating Leads to Contractors Call Slides and Discussion Summary February 26, 2015 Call Participants  Build It Green  City of Chula Vista  City of Philadelphia  Civic Works/Retrofit Baltimore  Clean Energy Durham  Clean Energy Works  Community Office for Resource Efficiency  Dr. Energy Saver  Efficiency Maine  Efficiency Nova Scotia  Energy Efficiency Specialists, LLC  Energy Pioneer Solutions  Greater

  18. Post regulation circuit with energy storage

    DOE Patents [OSTI]

    Ball, Don G.; Birx, Daniel L.; Cook, Edward G.

    1992-01-01

    A charge regulation circuit provides regulation of an unregulated voltage supply and provides energy storage. The charge regulation circuit according to the present invention provides energy storage without unnecessary dissipation of energy through a resistor as in prior art approaches.

  19. Output-Based Regulations: A Handbook for Air Regulators (U.S...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Output-Based Regulations: A Handbook for Air Regulators (U.S. EPA), August 2004 Output-Based Regulations: A Handbook for Air Regulators (U.S. EPA), August 2004 The U.S. ...

  20. Progress toward risk informed regulation

    SciTech Connect (OSTI)

    Rogers, K.C.

    1997-01-01

    For the last several years, the NRC, with encouragement from the industry, has been moving in the direction of risk informed regulation. This is consistent with the regulatory principle of efficiency, formally adopted by the Nuclear Regulatory Commission in 1991, which requires that regulatory activities be consistent with the degree of risk reduction they achieve. Probabilistic risk analysis has become the tool of choice for selecting the best of several alternatives. Closely related to risk informed regulation is the development of performance based rules. Such rules focus on the end result to be achieved. They do not specify the process, but instead establish the goals to be reached and how the achievement of those goals is to be judged. The inspection and enforcement activity is based on whether or not the goals have been met. The author goes on to offer comments on the history of the development of this process and its probable development in the future. He also addresses some issues which must be resolved or at least acknowledged. The success of risk informed regulation ultimately depends on having sufficiently reliable data to allow quantification of regulatory alternatives in terms of relative risk. Perhaps the area of human reliability and organizational performance has the greatest potential for improvement in reactor safety. The ability to model human performance is significantly less developed that the ability to model mechanical or electrical systems. The move toward risk informed, performance based regulation provides an unusual, perhaps unique, opportunity to establish a more rational, more effective basis for regulation.

  1. Phosphonic acid based exchange resins

    DOE Patents [OSTI]

    Horwitz, E.P.; Alexandratos, S.D.; Gatrone, R.C.; Chiarizia, R.

    1995-09-12

    An ion exchange resin is described for extracting metal ions from a liquid waste stream. An ion exchange resin is prepared by copolymerizing a vinylidene diphosphonic acid with styrene, acrylonitrile and divinylbenzene. 10 figs.

  2. Phosphonic acid based exchange resins

    DOE Patents [OSTI]

    Horwitz, E. Philip; Alexandratos, Spiro D.; Gatrone, Ralph C.; Chiarizia, Ronato

    1995-01-01

    An ion exchange resin for extracting metal ions from a liquid waste stream. An ion exchange resin is prepared by copolymerizing a vinylidene diphosphonic acid with styrene, acrylonitrile and divinylbenzene.

  3. Nucleic acid arrays and methods of synthesis

    DOE Patents [OSTI]

    Sabanayagam, Chandran R.; Sano, Takeshi; Misasi, John; Hatch, Anson; Cantor, Charles

    2001-01-01

    The present invention generally relates to high density nucleic acid arrays and methods of synthesizing nucleic acid sequences on a solid surface. Specifically, the present invention contemplates the use of stabilized nucleic acid primer sequences immobilized on solid surfaces, and circular nucleic acid sequence templates combined with the use of isothermal rolling circle amplification to thereby increase nucleic acid sequence concentrations in a sample or on an array of nucleic acid sequences.

  4. International Electricity Regulation | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Regulation International Electricity Regulation U.S. trade in electric energy with Canada and Mexico is rising, bringing economic and reliability benefits to the United States and ...

  5. Searchable Electronic Department of Energy Acquisition Regulation...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Searchable Electronic Department of Energy Acquisition Regulation Searchable Electronic Department of Energy Acquisition Regulation Updated July 2, 2013. The EDEAR is current ...

  6. Department of Energy Acquisition Regulation (DEAR) Technical...

    Broader source: Energy.gov (indexed) [DOE]

    of Energy Acquisition Regulation (DEAR) Technical Amendment-Final Rule (172.78 KB) More Documents & Publications Department of Energy Acquisition Regulation (DEAR) Technical ...

  7. Fish Habitat Regulations | Open Energy Information

    Open Energy Info (EERE)

    Fish Habitat Regulations Jump to: navigation, search OpenEI Reference LibraryAdd to library Web Site: Fish Habitat Regulations Author Alaska Department of Fish & Game Published...

  8. Alaska ADEC Wetlands Regulation | Open Energy Information

    Open Energy Info (EERE)

    Wetlands Regulation Jump to: navigation, search OpenEI Reference LibraryAdd to library Web Site: Alaska ADEC Wetlands Regulation Author Alaska Division of Water Published Alaska...

  9. HUD lead-based-paint abatement demonstration (FHA)

    SciTech Connect (OSTI)

    Not Available

    1991-08-01

    The toxic effects of lead on human beings, and particularly on young children, have been known for many years. Amendments to the Lead-Based Paint Poisoning Prevention Act (LPPPA) in 1987 and 1988 required the U.S. Department of Housing and Urban Development (HUD) to undertake a lead-based paint abatement demonstration program. The overall objective of the demonstration was to 'utilize a sufficient number of abatement methods in a sufficient number of areas and circumstances to demonstrate their relative cost-effectiveness...' One component of the demonstration was conducted in HUD-owned, vacant, single-family properties and was completed in the fall of 1990. A public housing component is expected to be completed in 1991. The report describes the objectives, research design, experience and findings of the completed component, which is generally known as the FHA demonstration, named after the Federal Housing Administration, which held title to the houses.

  10. An ortholog of farA of Aspergillus nidulans is implicated in the transcriptional activation of genes involved in fatty acid utilization in the yeast Yarrowia lipolytica

    SciTech Connect (OSTI)

    Poopanitpan, Napapol; Kobayashi, Satoshi; Fukuda, Ryouichi; Horiuchi, Hiroyuki; Ohta, Akinori

    2010-11-26

    Research highlights: {yields} POR1 is a Yarrowia lipolytica ortholog of farA involved in fatty acid response in A. nidulans. {yields} Deletion of POR1 caused growth defects on fatty acids. {yields} {Delta}por1 strain exhibited defects in the induction of genes involved in fatty acid utilization. -- Abstract: The yeast Yarrowia lipolytica effectively utilizes hydrophobic substrates such as fatty acids and n-alkanes. To identify a gene(s) regulating fatty acid utilization in Y. lipolytica, we first studied homologous genes to OAF1 and PIP2 of Saccharomyces cerevisiae, but their disruption did not change growth on oleic acid at all. We next characterized a Y. lipolytica gene, POR1 (primary oleate regulator 1), an ortholog of farA encoding a transcriptional activator that regulates fatty acid utilization in Aspergillus nidulans. The deletion mutant of POR1 was defective in the growth on various fatty acids, but not on glucose, glycerol, or n-hexadecane. It exhibited slight defect on n-decane. The transcriptional induction of genes involved in {beta}-oxidation and peroxisome proliferation by oleate was distinctly diminished in the {Delta}por1 strains. These data suggest that POR1 encodes a transcriptional activator widely regulating fatty acid metabolism in Y. lipolytica.

  11. Photodissociation dynamics of hydroxybenzoic acids

    SciTech Connect (OSTI)

    Yang Yilin; Dyakov, Yuri; Lee, Y. T.; Ni, Chi-Kung; Sun Yilun; Hu Weiping

    2011-01-21

    Aromatic amino acids have large UV absorption cross-sections and low fluorescence quantum yields. Ultrafast internal conversion, which transforms electronic excitation energy to vibrational energy, was assumed to account for the photostability of amino acids. Recent theoretical and experimental investigations suggested that low fluorescence quantum yields of phenol (chromophore of tyrosine) are due to the dissociation from a repulsive excited state. Radicals generated from dissociation may undergo undesired reactions. It contradicts the observed photostability of amino acids. In this work, we explored the photodissociation dynamics of the tyrosine chromophores, 2-, 3- and 4-hydroxybenzoic acid in a molecular beam at 193 nm using multimass ion imaging techniques. We demonstrated that dissociation from the excited state is effectively quenched for the conformers of hydroxybenzoic acids with intramolecular hydrogen bonding. Ab initio calculations show that the excited state and the ground state potential energy surfaces change significantly for the conformers with intramolecular hydrogen bonding. It shows the importance of intramolecular hydrogen bond in the excited state dynamics and provides an alternative molecular mechanism for the photostability of aromatic amino acids upon irradiation of ultraviolet photons.

  12. ISOs: The new antitrust regulators?

    SciTech Connect (OSTI)

    Raskin, D.B.

    1998-04-01

    Fear of seller market power in emerging electricity markets has led regulators to sanction use of independent system operators as private market police. A more restrained approach is likely to yield better results without the chilling effects of private regulation. This new industry regulatory paradigm has received little critical attention to date. This is unfortunate because ISO antitrust regulation raises serious legal and policy concerns. The California and New England Power Pool (NEPOOL) plans are quite intrusive. They require the ISO to make difficult distinctions between acceptable and unacceptable market behavior. They create considerable risk that desirable competitive behavior will be chilled and that market participants will incur significant explicit and implicit costs to meet regulatory requirements.

  13. Differential regulation of HIF-1α and HIF-2α in neuroblastoma: Estrogen-related receptor alpha (ERRα) regulates HIF2A transcription and correlates to poor outcome

    SciTech Connect (OSTI)

    Hamidian, Arash; Stedingk, Kristoffer von; Munksgaard Thorén, Matilda; Mohlin, Sofie; Påhlman, Sven

    2015-06-05

    Hypoxia-inducible factors (HIFs) are differentially regulated in tumor cells. While the current paradigm supports post-translational regulation of the HIF-α subunits, we recently showed that hypoxic HIF-2α is also transcriptionally regulated via insulin-like growth factor (IGF)-II in the childhood tumor neuroblastoma. Here, we demonstrate that transcriptional regulation of HIF-2α seems to be restricted to neural cell-derived tumors, while HIF-1α is canonically regulated at the post-translational level uniformly across different tumor forms. Enhanced expression of HIF2A mRNA at hypoxia is due to de novo transcription rather than increased mRNA stability, and chemical stabilization of the HIF-α proteins at oxygen-rich conditions unexpectedly leads to increased HIF2A transcription. The enhanced HIF2A levels do not seem to be dependent on active HIF-1. Using a transcriptome array approach, we identified members of the Peroxisome proliferator-activated receptor gamma coactivator (PGC)/Estrogen-related receptor (ERR) complex families as potential regulators of HIF2A. Knockdown or inhibition of one of the members, ERRα, leads to decreased expression of HIF2A, and high expression of the ERRα gene ESRRA correlates with poor overall and progression-free survival in a clinical neuroblastoma material consisting of 88 tumors. Thus, targeting of ERRα and pathways regulating transcriptional HIF-2α are promising therapeutic avenues in neuroblastoma. - Highlights: • Transcriptional control of HIF-2α is restricted to neural cell-derived tumors. • Enhanced transcription of HIF2A is not due to increased mRNA stability. • Chemical stabilization of the HIF-α subunits leads to increased HIF2A transcription. • ERRα regulates HIF2A mRNA expression in neuroblastoma. • High expression of ESRRA correlates to poor outcome in neuroblastoma.

  14. In vivo incorporation of unnatural amino acids

    DOE Patents [OSTI]

    Schultz, Peter G.; Wang, Lei; Anderson, John Christopher; Chin, Jason W.; Liu, David R.; Magliery, Thomas J.; Meggers, Eric L.; Mehl, Ryan Aaron; Pastrnak, Miro; Santoro, Stephen William; Zhang, Zhiwen

    2012-05-08

    The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids.

  15. In vivo incorporation of unnatural amino acids

    DOE Patents [OSTI]

    Schultz, Peter G.; Wang, Lei; Anderson, John Christopher; Chin, Jason W.; Liu, David R.; Magliery, Thomas J.; Meggers, Eric L.; Mehl, Ryan Aaron; Pastrnak, Miro; Santoro, Stephen William; Zhang, Zhiwen

    2011-10-04

    The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids.

  16. In vivo incorporation of unnatural amino acids

    DOE Patents [OSTI]

    Schultz, Peter; Wang, Lei; Anderson, John Christopher; Chin, Jason W.; Liu, David R.; Magliery, Thomas J.; Meggers, Eric; Mehl, Ryan Aaron; Pastrnak, Miro; Santoro, Stephen William; Zhang, Zhiwen

    2011-03-29

    The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids.

  17. In vivo incorporation of unnatural amino acids

    DOE Patents [OSTI]

    Schultz, Peter G.; Wang, Lei; Anderson, John Christopher; Chin, Jason W.; Liu, David R.; Magliery, Thomas J.; Meggers, Eric L.; Mehl, Ryan Aaron; Pastrnak, Miro; Santoro, Stephen William; Zhang, Zhiwen

    2012-02-14

    The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids.

  18. In vivo incorporation of unnatural amino acids

    DOE Patents [OSTI]

    Schultz, Peter; Wang, Lei; Anderson, John Christopher; Chin, Jason W.; Liu, David R.; Magliery, Thomas J.; Meggers, Eric; Mehl, Ryan Aaron; Pastrnak, Miro; Santoro, Steven William; Zhang, Zhiwen

    2008-05-06

    The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids.

  19. Acid soluble, pepsin resistant platelet aggregating material

    DOE Patents [OSTI]

    Schneider, Morris D.

    1982-08-31

    Acid soluble, pepsin resistant, platelet aggregating material isolated from equine arterial tissue by extraction with dilute aqueous acid, method of isolation and use to control bleeding.

  20. In vivo incorporation of unnatural amino acids

    DOE Patents [OSTI]

    Schultz, Peter; Wang, Lei; Anderson, John Christopher; Chin, Jason William; Liu, David R.; Magliery, Thomas J.; Meggers, Eric L.; Mehl, Ryan A.; Pastrnak, Miro; Santoro, Steven William; Zhang, Zhiwen

    2006-05-16

    The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids.

  1. In vivo incorporation of unnatural amino acids

    DOE Patents [OSTI]

    Schultz, Peter; Wang, Lei; Anderson, John Christopher; Chin, Jason W.; Liu, David R.; Magliery, Thomas J.; Meggers, Eric; Mehl, Ryan Aaron; Pastrnak, Miro

    2009-12-29

    The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids

  2. Beyond Ketonization: Selective Conversion of Carboxylic Acids...

    Office of Scientific and Technical Information (OSTI)

    Title: Beyond Ketonization: Selective Conversion of Carboxylic Acids to Olefins over Balanced Lewis Acid-base Pairs Dwindling petroleum reserves combined with increased energy ...

  3. Methods for measuring lead concentrations in paint films

    SciTech Connect (OSTI)

    McKnight, M.E.; Byrd, W.E.; Roberts, W.E.; Lagergren, E.S.

    1989-12-01

    Recent legislation required the U.S. Department of Housing and Urban Development (HUD) to establish procedures to abate lead-based paint in existing HUD-assisted housing. The legislation also required HUD to assess the accuracy, precision, reliability, and safety of methods for measuring lead content of paint films and to investigate the availability of testers and samplers. The National Institute of Standards and Technology was requested to carry out the assessment. With regard to accuracy and precision of field measurements, it was concluded that: chemical spot tests when carried out by an experienced analytical chemistry technician can detect the presence of lead in paint films having concentrations in excess of 1 mg/sq cm about 90% of the time; the estimate of the precision of a field measurement procedure using lead-specific portable X-ray fluorescence (XRF) analyzers for lead concentrations near 1 mg/sq cm is + or - 0.6 mg/sq cm and the estimate of the bias is 0.2 mg/sq cm; this results in a 95% confidence interval of + or - 1.4 mg/sq cm; and based upon very preliminary measurements using the latest version of the spectrum analyzer portable XRF, the 95% confidence interval for field measurements is estimated to be + or - 0.5 mg/sq cm. In addition to field methods, standard laboratory procedures can be used to measure the lead content of paint samples to within a few percent of the quantity present over a wide range extending from less than 0.1 to over 10 mg/sq cm. Sample collection and sample dissolution procedures were also investigated.

  4. Recent advances in yeast molecular biology: recombinant DNA. [Lead abstract

    SciTech Connect (OSTI)

    Not Available

    1982-09-01

    Separate abstracts were prepared for the 25 papers presented at a workshop focusing on chromosomal structure, gene regulation, recombination, DNA repair, and cell type control, that have been obtained by experimental approaches incorporating the new technologies of yeast DNA transformation, molecular cloning, and DNA sequence analysis. (KRM)

  5. Nation Leads Wind Energy Production and Innovation | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Nation Leads Wind Energy Production and Innovation Nation Leads Wind Energy Production and Innovation May 11, 2016 - 12:19pm Addthis Letter from the Wind Program Director This spring edition of the Wind Program Newsletter comes at the juncture of two important events for the wind industry: the 1-year anniversary of the U.S. Department of Energy Wind Program's historic Wind Vision Report and the start of American Wind Energy Association (AWEA) WINDPOWER 2016. We have quite a bit to celebrate this

  6. Research Leads to Improved Fuel Yields from Smaller Antenna Algae |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Research Leads to Improved Fuel Yields from Smaller Antenna Algae Research Leads to Improved Fuel Yields from Smaller Antenna Algae May 13, 2014 - 12:06pm Addthis Tasios Melis (center) shows plates with tla3 algae and its parent strain to Katie Randolph (left) and Sunita Satyapal during a site visit to his lab at the University of California, Berkeley. Tasios Melis (center) shows plates with tla3 algae and its parent strain to Katie Randolph (left) and Sunita Satyapal

  7. Fundamental studies and new applications of hybrid lead halide perovskites*

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    | MIT-Harvard Center for Excitonics Fundamental studies and new applications of hybrid lead halide perovskites* November 10, 2015 at 4:30pm/Duboc Room: 4-331 Riccardo Comin University of Toronto comin-1 In recent years light-harvesting devices based on a new class of organometallic lead iodide perovskites (CH3NH3PbI3) were demonstrated to exhibit power conversion efficiencies beyond 20%, rapidly approaching the performance of commercial silicon-based modules. Besides photovoltaics, important

  8. GE leads the way in photonics research | GE Global Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GE continues leading role in photonics industry - from LED to digital x-ray Click to email this to a friend (Opens in new window) Share on Facebook (Opens in new window) Click to share (Opens in new window) Click to share on LinkedIn (Opens in new window) Click to share on Tumblr (Opens in new window) GE continues leading role in photonics industry - from LED to digital x-ray Danielle Merfeld, Ph.D. 2015.07.27 Vice President Joseph Biden joined New York Gov. Andrew Cuomo in Rochester, New York

  9. INFOGRAPHIC: Better Buildings Leading to Big Energy Savings | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Better Buildings Leading to Big Energy Savings INFOGRAPHIC: Better Buildings Leading to Big Energy Savings May 11, 2016 - 12:35pm Addthis Better Buildings partners have saved more than $1.3 billion on energy costs. Our new infographic explains how Better Buildings works and why it’s important. | Graphic by <a href="/node/1332956">Carly Wilkins</a>, Energy Department Better Buildings partners have saved more than $1.3 billion on energy costs. Our new

  10. Comparison of leading parallel NAS file systems on commodity hardware

    SciTech Connect (OSTI)

    Hedges, R; Fitzgerald, K; Gary, M; Stearman, D M

    2010-11-08

    High performance computing has experienced tremendous gains in system performance over the past 20 years. Unfortunately other system capabilities, such as file I/O, have not grown commensurately. In this activity, we present the results of our tests of two leading file systems (GPFS and Lustre) on the same physical hardware. This hardware is the standard commodity storage solution in use at LLNL and, while much smaller in size, is intended to enable us to learn about differences between the two systems in terms of performance, ease of use and resilience. This work represents the first hardware consistent study of the two leading file systems that the authors are aware of.

  11. Saturation of the leading spike growth in backward Raman amplifiers

    SciTech Connect (OSTI)

    Malkin, V. M.; Fisch, N. J.; Toroker, Z.

    2014-09-15

    Backward Raman amplification of laser pulses in plasmas can produce nearly relativistic unfocused output intensities and multi-exawatt powers in compact devices. The largest achievable intensity depends on which of major competitive processes set this limit. It is shown here that the relativistic electron nonlinearity can cause saturation of the leading amplified spike intensity before filamentation instabilities develop. A simple analytical model for the saturation, which supports numerical simulations, is suggested. The upper limit for the leading output spike unfocused intensity is calculated.

  12. Cities Leading through Energy Analysis and Planning | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Us » Initiatives & Projects » Cities Leading through Energy Analysis and Planning Cities Leading through Energy Analysis and Planning Find energy use data for your city! Find energy use data for your city! Read more View this infographic to learn more about the Cities-LEAP report. View this infographic to learn more about the Cities-LEAP report. Read more Cities-LEAP analysis reveals energy focus for 20 cities. Cities-LEAP analysis reveals energy focus for 20 cities. Read more The Cities

  13. National Labs Leading Charge on Building Better Batteries | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Labs Leading Charge on Building Better Batteries National Labs Leading Charge on Building Better Batteries September 26, 2011 - 12:36pm Addthis Berkeley Lab researchers have designed a new anode -- a key component of lithium ion batteries -- made from a "tailored polymer" (pictured above at right in purple). It has a greater capacity to store energy since it can conduct electricity itself rather than using a polymer binder (such as PVDF, pictured above at left in brown) in

  14. Large-scale production of anhydrous nitric acid and nitric acid solutions of dinitrogen pentoxide

    DOE Patents [OSTI]

    Harrar, Jackson E.; Quong, Roland; Rigdon, Lester P.; McGuire, Raymond R.

    2001-01-01

    A method and apparatus are disclosed for a large scale, electrochemical production of anhydrous nitric acid and N.sub.2 O.sub.5. The method includes oxidizing a solution of N.sub.2 O.sub.4 /aqueous-HNO.sub.3 at the anode, while reducing aqueous HNO.sub.3 at the cathode, in a flow electrolyzer constructed of special materials. N.sub.2 O.sub.4 is produced at the cathode and may be separated and recycled as a feedstock for use in the anolyte. The process is controlled by regulating the electrolysis current until the desired products are obtained. The chemical compositions of the anolyte and catholyte are monitored by measurement of the solution density and the concentrations of N.sub.2 O.sub.4.

  15. Genome sequencing of the Trichoderma reesei QM9136 mutant identifies a truncation of the transcriptional regulator XYR1 as the cause for its cellulase-negative phenotype

    SciTech Connect (OSTI)

    Lichius, Alexander; Bidard, Frederique; Buchholz, Franziska; Le Crom, Stphane; Martin, Joel X.; Schackwitz, Wendy; Austerlitz, Tina; Grigoriev, Igor V.; Baker, Scott E.; Margeot, Antoine; Seiboth, Bernhard; Kubicek, Christian P.

    2015-12-01

    Background: Trichoderma reesei is the main industrial source of cellulases and hemicellulases required for the hydrolysis of biomass to simple sugars, which can then be used in the production of biofuels and biorefineries. The highly productive strains in use today were generated by classical mutagenesis. As byproducts of this procedure, mutants were generated that turned out to be unable to produce cellulases. In order to identify the mutations responsible for this inability, we sequenced the genome of one of these strains, QM9136, and compared it to that of its progenitor T. reesei QM6a. Results: In QM9136, we detected a surprisingly low number of mutagenic events in the promoter and coding regions of genes, i.e. only eight indels and six single nucleotide variants. One of these indels led to a frame-shift in the Zn2Cys6 transcription factor XYR1, the general regulator of cellulase and xylanase expression, and resulted in its C-terminal truncation by 140 amino acids. Retransformation of strain QM9136 with the wild-type xyr1 allele fully recovered the ability to produce cellulases, and is thus the reason for the cellulase-negative phenotype. Introduction of an engineered xyr1 allele containing the truncating point mutation into the moderate producer T. reesei QM9414 rendered this strain also cellulase-negative. The correspondingly truncated XYR1 protein was still able to enter the nucleus, but failed to be expressed over the basal constitutive level. Conclusion: The missing 140 C-terminal amino acids of XYR1 are therefore responsible for its previously observed auto-regulation which is essential for cellulases to be expressed. Our data present a working example of the use of genome sequencing leading to a functional explanation of the QM9136 cellulase-negative phenotype.

  16. DOE Leads National Research Program in Gas Hydrates

    Broader source: Energy.gov [DOE]

    The U.S. Department of Energy today told Congress the agency is leading a nationwide program in search of naturally occurring natural gas hydrates - a potentially significant storehouse of methane--with far reaching implications for the environment and the nation's future energy supplies.

  17. Novel class of amino acid antagonists at non-N-methyl-D-aspartic acid excitatory amino acid receptors. Synthesis, in vitro and in vivo pharmacology, and neuroprotection

    SciTech Connect (OSTI)

    Krogsgaard-Larsen, P.; Ferkany, J.W.; Nielsen, E.O.; Madsen, U.; Ebert, B.; Johansen, J.S.; Diemer, N.H.; Bruhn, T.; Beattie, D.T.; Curtis, D.R. )

    1991-01-01

    The isoxazole amino acid 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl) propionic acid (AMPA) (1), which is a highly selective agonist at the AMPA subtype of excitatory amino acid (EAA) receptors, has been used as a lead for the development of two novel EAA receptor antagonists. One of the compounds, 2-amino-3-(3-(carboxymethoxy)-5-methylisoxazol-4-yl)propionic acid (AMOA, 7), was synthesized via O-alkylation by ethyl chloroacetate of the amino acid protected AMPA derivative 4. The other compound, 2-amino-3-(2-(3-hydroxy-5-methylisoxazol-4-yl)-methyl-5-methyl-3-+ ++oxoisoxazolin -4-yl)propionic acid (AMNH, 14) was synthesized with use of 4-(chloromethyl)-3-methoxy-5-methylisoxazole (8) as the starting material. The intermediate 4-(chloromethyl)-2-(3-methoxy-5-methylisoxazol-4-yl)methyl-5-me thylisoxazolin- 3-one (11) was converted into the acetamidomalonate (12), which was stepwise deprotected to give 14. Compounds 7 and 14 were stable in aqueous solution at pH values close to physiological pH. Neither 7 nor 14 showed detectable affinities for the receptor, ion channel, or modulatory sites of the N-methyl-D-aspartic acid (NMDA) receptor complex. Quantitative receptor autoradiographic and conventional binding techniques were used to study the affinities of 7 and 14 for non-NMDA receptor sites. Both compounds were inhibitors of the binding of (3H)AMPA (IC50 = 90 and 29 microM, respectively). Compounds 14 and 7 were both very weak inhibitors of the high-affinity binding of radioactive kainic acid ((3H)KAIN). Compound 14, but not 7, was, however, shown to be an inhibitor of low-affinity (3H)KAIN binding as determined in the presence of 100 mM calcium chloride. In the rat cortical slice preparation, 7 was shown to antagonize excitation induced by 1 with some selectivity, whereas 14 proved to be a rather selective antagonist of KAIN-induced excitation.

  18. Evaluation of potential mixed wastes containing lead, chromium, or used oil

    SciTech Connect (OSTI)

    Siskind, B.; MacKenzie, D.R.; Bowerman, B.S.; Kempf, C.R.; Piciulo, P.L.

    1987-01-01

    This paper presents the results of follow-on studies conducted by Brookhaven National Laboratory (BNL) for the Nuclear Regulatory Commission (NRC) on certain kinds of low-level waste (LLW) which could also be classified as hazardous waste subject to regulation by the Environmental Protection Agency (EPA). Such LLW is termed ''mixed waste.'' Additional data have been collected and evaluated on two categories of potential mixed waste, namely LLW containing metallic lead and LLW containing chromium. Additionally, LLW with organic liquids, especially liquid scintillation wastes, are reviewed. In light of a proposed EPA rule to list used oil as hazardous waste, the potential mixed waste hazard of used oil contaminated with radionuclides is discussed. It is concluded that the EPA test for determining whether a solid waste exhibits the hazardous characteristic of extraction procedure toxicity does not adequately simulate the burial environment at LLW disposal sites, and in particular, does not adequately assess the potential for dissolution and transport of buried metallic lead. Also, although chromates are, in general, not a normal or routine constitutent in commercial LLW (with the possible exception of chemical decontamination wastes), light water reactors which do use chromates might find it beneficial to consider alternative corrosion inhibitors. In addition, it is noted that if used oil is listed by the EPA as hazardous waste, LLW oil may be managed by a scheme including one or more of the following processes: incineration, immobilization, sorption, aqueous extraction and glass furnace processing.

  19. A blasting additive that renders wastes non hazardous in lead paint abatement projects

    SciTech Connect (OSTI)

    Clark, R.; Rapp, D.J.; McGrew, M.

    1994-12-31

    Maintenance of steel structures often produces abrasive wastes that are considered toxic and hazardous due to the lead content of the old paint system present in spent abrasives. Environmental regulations in the US and Canada effectively preclude on-site treatment and disposal of these wastes, thereby forcing them into costly transport and secure disposal options. The authors have developed an abrasive additive that allows dry or wet blasting to remove old paint systems, but the resultant wastes are considered non-hazardous and are eligible for recycling or non-hazardous waste disposal, both at sharply reduced costs. The agent does not ``mask`` environmental test results, but does produce a stable residue suitable for long term disposal or reuse. Surface conditions after application of abrasives appear to be amenable to virtually all paint systems tested. The process is in use on an estimated 10% of all steel based lead paint abatement projects in the US, and is experiencing considerable growth in market acceptance. The technology may allow disposal cost reductions in excess of 50%.

  20. Chapter 2 of the Wyoming Public Service Commission Regulations...

    Open Energy Info (EERE)

    2 of the Wyoming Public Service Commission Regulations: General Regulations Jump to: navigation, search OpenEI Reference LibraryAdd to library Legal Document- RegulationRegulation:...

  1. Allowance trading activity and state regulatory rulings: Evidence from the US Acid Rain Program

    SciTech Connect (OSTI)

    Bailey, E.M.

    1997-12-31

    The US Acid Rain Program is one of the first, and by far the most extensive, applications of a market based approach to pollution control. From the beginning, there has been concern whether utilities would participate in allowance trading, and whether regulatory activity at the state level would further complicate utilities` decision to trade allowances. This paper finds that public utility commission regulation has encouraged allowance trading activity in states with regulatory rulings, but that allowance trading activity has not been limited to states issuing regulations. Until there is evidence suggesting that significant additional cost savings could have been obtained if additional allowance trading activity had occurred in states without regulations or that utilities in states with regulations are still not taking advantage of all cost saving trading opportunities, this analysis suggests that there is little reason to believe that allowance trading activity is impeded by public utility commission regulations.

  2. Acid sorption regeneration process using carbon dioxide

    DOE Patents [OSTI]

    King, C. Judson; Husson, Scott M.

    2001-01-01

    Carboxylic acids are sorbed from aqueous feedstocks onto a solid adsorbent in the presence of carbon dioxide under pressure. The acids are freed from the sorbent phase by a suitable regeneration method, one of which is treating them with an organic alkylamine solution thus forming an alkylamine-carboxylic acid complex which thermally decomposes to the desired carboxylic acid and the alkylamine.

  3. Crushing leads to waste disposal savings for FUSRAP

    SciTech Connect (OSTI)

    Darby, J.

    1997-02-01

    In this article the author discusses the application of a rock crusher as a means of implementing cost savings in the remediation of FUSRAP sites. Transportation and offsite disposal costs are at present the biggest cost items in the remediation of FUSRAP sites. If these debris disposal problems can be handled in different manners, then remediation savings are available. Crushing can result in the ability to handle some wastes as soil disposal problems, which have different disposal regulations, thereby permitting cost savings.

  4. Rainwater Harvesting Regulations Map | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Regulations Map Rainwater Harvesting Regulations Map Rainwater collection is currently regulated by individual states. There was no centralized information source on state-level regulations on rainwater harvesting maintained by a federal agency. To fill this information gap, the Federal Energy Management Program compiled state-level information and provided it in this map tool. How to Use the Map This map gives federal agencies key information on how rainwater is regulated across the U.S. to

  5. High speed nucleic acid sequencing

    DOE Patents [OSTI]

    Korlach, Jonas; Webb, Watt W.; Levene, Michael; Turner, Stephen; Craighead, Harold G.; Foquet, Mathieu

    2011-05-17

    The present invention is directed to a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the polymerization reaction is measured on a molecule of nucleic acid. Each type of labeled nucleotide comprises an acceptor fluorophore attached to a phosphate portion of the nucleotide such that the fluorophore is removed upon incorporation into a growing strand. Fluorescent signal is emitted via fluorescent resonance energy transfer between the donor fluorophore and the acceptor fluorophore as each nucleotide is incorporated into the growing strand. The sequence is deduced by identifying which base is being incorporated into the growing strand.

  6. Next-to-leading order predictions for WW + jet production

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Campbell, John M.; Miller, David J.; Robens, Tania

    2015-07-28

    In this study we report on a next-to-leading order calculation of WW + jet production at hadron colliders, with subsequent leptonic decays of the W bosons included. The calculation of the one-loop contributions is performed using generalized unitarity methods in order to derive analytic expressions for the relevant amplitudes. These amplitudes have been implemented in the parton-level Monte Carlo generator mcfm, which we use to provide a complete next-to-leading order calculation. Predictions for total cross sections, as well as differential distributions for several key observables, are computed both for the LHC operating at 14 TeV as well as for amore » possible future 100 TeV proton-proton collider.« less

  7. Next-to-leading order predictions for WW + jet production

    SciTech Connect (OSTI)

    Campbell, John M.; Miller, David J.; Robens, Tania

    2015-07-28

    In this study we report on a next-to-leading order calculation of WW + jet production at hadron colliders, with subsequent leptonic decays of the W bosons included. The calculation of the one-loop contributions is performed using generalized unitarity methods in order to derive analytic expressions for the relevant amplitudes. These amplitudes have been implemented in the parton-level Monte Carlo generator mcfm, which we use to provide a complete next-to-leading order calculation. Predictions for total cross sections, as well as differential distributions for several key observables, are computed both for the LHC operating at 14 TeV as well as for a possible future 100 TeV proton-proton collider.

  8. An alternative to removing lead-based paint: Overcoating

    SciTech Connect (OSTI)

    Vernon, L.S.

    1996-02-01

    The case of repairing a municipal water tank coated with lead-based paint (LBP) is used to illustrate some of the benefits of overcoating, a possible alternative to removing failing paint. The paper discusses data regarding performance of the waterborne acrylic used in the case study, briefly reviews revisions to specifications for the coating`s use, and offers some costs by which to compare use of a waterborne encapsulant such as that used in the case study with either removal and recoating or use of a solvent-borne encapsulant. A surface-tolerant, water-based, corrosion-resistant acrylic was selected to overcoat the LBP. By cleaning and overcoating the existing adherent LBP using the acrylic coating, chances of lead exposure to workers and the public were reduced. Eliminating abrasive blasting and the need for full containment saved about $80,000 to $100,000.

  9. Entropically stabilized local dipole formation in lead chalcogenides.

    SciTech Connect (OSTI)

    Bozin, E. S.; Malliakas, C. D.; Souvatzis, P.; Proffen, T.; Spaldin, N. A.; Kanatzidis, M. G.; Billinge, S. J. L.; Materials Science Division; Brookhaven Nat. Lab.; Northwestern Univ.; Los Alamos Nat. Lab.; ETH, Zurich; Columbia Univ.

    2010-12-17

    We report the observation of local structural dipoles that emerge from an undistorted ground state on warming, in contrast to conventional structural phase transitions in which distortions emerge on cooling. Using experimental and theoretical probes of the local structure, we demonstrate this behavior in binary lead chalcogenides, which were believed to adopt the ideal, undistorted rock-salt structure at all temperatures. The behavior is consistent with a simple thermodynamic model in which the emerging dipoles are stabilized in the disordered state at high temperature due to the extra configurational entropy despite the fact that the undistorted structure has lower internal energy. Our findings shed light on the anomalous electronic and thermoelectric properties of the lead chalcogenides. Similar searches may show that the phenomenon is more widespread.

  10. Lead and cadmium concentrations in livestock bred in Campania, Italy

    SciTech Connect (OSTI)

    Amodio-Cocchieri, R.; Fiore, P.

    1987-09-01

    Among the various aspects of environmental pollution, special attention must be directed to heavy metals, which show a remarkable tendency to accumulate in tissues and organs of animals and humans. Particularly, lead and cadmium are of great concern when one considers that the variety of their uses has increased their level in the environment and that they have been identified as the causes of several clinical problems. Since heavy metals may be used as indicators of industrial contamination, the Italian Ministry of Health started a research program concerning the lead and cadmium levels in meat, cow's milk and eggs produce by Italian livestock and in well water, and in local and industrial feeds tuffs employed in their breeding. This is the object of the present study carried out in the Campania province.

  11. Identifying a base in a nucleic acid

    DOE Patents [OSTI]

    Fodor, Stephen P. A.; Lipshutz, Robert J.; Huang, Xiaohua

    2005-02-08

    Devices and techniques for hybridization of nucleic acids and for determining the sequence of nucleic acids. Arrays of nucleic acids are formed by techniques, preferably high resolution, light-directed techniques. Positions of hybridization of a target nucleic acid are determined by, e.g., epifluorescence microscopy. Devices and techniques are proposed to determine the sequence of a target nucleic acid more efficiently and more quickly through such synthesis and detection techniques.

  12. NREL Technique Leads to Improved Perovskite Solar Cells - News Releases |

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NREL NREL Technique Leads to Improved Perovskite Solar Cells August 1, 2016 Photo shows a man looking at a handful of solar cells made of perovskite. NREL researcher Mengjin Yang examines hybrid perovskite solar cells in his lab. (Photo by Dennis Schroeder / NREL) Scientists at the Energy Department's National Renewable Energy Laboratory (NREL), in collaboration with researchers at Shanghai Jiao Tong University (SJTU), devised a method to improve perovskite solar cells, making them more

  13. Huizenga leads safety of spent fuel management, radioactive waste

    National Nuclear Security Administration (NNSA)

    management meeting in Vienna | National Nuclear Security Administration | (NNSA) Huizenga leads safety of spent fuel management, radioactive waste management meeting in Vienna Tuesday, May 26, 2015 - 12:10pm NNSA Blog David Huizenga, NNSA's Principal Assistant Deputy Administrator for Defense Nuclear Nonproliferation, recently served as president of the Fifth Review Meeting of the Joint Convention on the Safety of Spent Fuel Management and on the Safety of Radioactive Waste Management at the

  14. Materials Physics and Applications Division Lead | National Nuclear

    National Nuclear Security Administration (NNSA)

    Security Administration | (NNSA) Materials Physics and Applications Division Lead Antoinette Taylor Toni Taylor November 2009 Los Alamos National Laboratory Fellow Six Los Alamos scientists have been designated 2009 Los Alamos National Laboratory Fellows in recognition of sustained, outstanding scientific contributions and exceptional promise for continued professional achievement. The title of Fellow is bestowed on only about 2 percent of the Laboratory's current technical staff. The new

  15. Greg Wilson to Lead National Center for Photovoltaics - News Releases |

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Greg Stewart About Us Greg Stewart - SLAC National Accelerator Laboratory Greg Stewart is a graphic designer for SLAC National Accelerator Laboratory, one of the Department of Energy's 17 National Laboratories. Most Recent Three Ways to Bust Ghostly Dark Matter March 30 NREL

    Greg Wilson to Lead National Center for Photovoltaics November 11, 2011 Photo of Dr. Gregory M. Wilson Dr. Gregory M. Wilson has been named director of the National Center for Photovoltaics at NREL. Dr. Gregory M.

  16. NNSA labs continue to lead national solar power evaluation effort |

    National Nuclear Security Administration (NNSA)

    National Nuclear Security Administration | (NNSA) labs continue to lead national solar power evaluation effort Friday, June 3, 2016 - 9:37am NNSA's laboratories have unique capabilities in modeling, simulation, performance prediction, and system design because of their vital role in the nuclear security enterprise. These capabilities have perfectly enabled NNSA's Sandia National Laboratories to help make solar technology a powerful part of the future for U.S. industry. Sandia recently won a

  17. Leading the Charge: Akwesasne Housing Authority Director Retha Herne |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Charge: Akwesasne Housing Authority Director Retha Herne Leading the Charge: Akwesasne Housing Authority Director Retha Herne October 28, 2015 - 9:02am Addthis Energy-efficient homes in AHA’s Sunrise Acres Complex include such features as rooftop solar domestic hot water. Photo from Akwesasne Housing Authority. Energy-efficient homes in AHA's Sunrise Acres Complex include such features as rooftop solar domestic hot water. Photo from Akwesasne Housing Authority.

  18. Novel Nanoparticle Production Method Could Lead to Better Lights, Lenses,

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Solar Cells Nanoparticle Production Method Could Lead to Better Lights, Lenses, Solar Cells - Sandia Energy Energy Search Icon Sandia Home Locations Contact Us Employee Locator Energy & Climate Secure & Sustainable Energy Future Stationary Power Energy Conversion Efficiency Solar Energy Wind Energy Water Power Supercritical CO2 Geothermal Natural Gas Safety, Security & Resilience of the Energy Infrastructure Energy Storage Nuclear Power & Engineering Grid Modernization

  19. Lester to lead ORISE's scientific and technical peer review program

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Lester to lead ORISE's scientific and technical peer review program FOR IMMEDIATE RELEASE June 14, 2010 FY10-42 OAK RIDGE, Tenn.-Oak Ridge Associated Universities has appointed Tony Lester as director of the Oak Ridge Institute for Science and Education's program focused on scientific peer review. Lester has been serving in this role in an acting capacity since September 2009. Tony Lester Tony Lester In his role, Lester manages a research peer review capability that coordinates the use of

  20. Director Arvizu Named Leading Hispanic in Science and Technology - News

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Releases | NREL Director Arvizu Named Leading Hispanic in Science and Technology Organization Promoting Technology Careers Awards Arvizu Highest Honor October 13, 2008 Dan Arvizu, who has served as director of the U.S. Department of Energy's (DOE) National Renewable Energy Laboratory (NREL) since 2005, was inducted into the Hispanic Engineer National Achievement Awards Conference (HENAAC) Hall of Fame at a ceremony in Houston, Texas on Saturday. The Hall of Fame's purpose is to

  1. Method of making a non-lead hollow point bullet

    DOE Patents [OSTI]

    Vaughn, Norman L.; Lowden, Richard A.

    2003-10-07

    The method of making a non-lead hollow point bullet has the steps of a) compressing an unsintered powdered metal composite core into a jacket, b) punching a hollow cavity tip portion into the core, c) seating an insert, the insert having a hollow point tip and a tail protrusion, on top of the core such that the tail protrusion couples with the hollow cavity tip portion, and d) swaging the open tip of the jacket.

  2. Non-lead, environmentally safe projectiles and explosives containers

    DOE Patents [OSTI]

    Lowden, Richard A.; McCoig, Thomas M.; Dooley, Joseph B.; Smith, Cyrus M.

    2001-01-16

    A solid object having controlled frangibility, such as a bullet or a container for explosives, is made by combining two different metals in proportions calculated to achieve a desired density, without using lead. A wetting material is deposited on the base constituent which is made of a relative dense, hard material. The wetting material enhances the wettability of the base constituent with the binder constituent, which is lighter and softer than the base constituent.

  3. Eliot Feibush leads new Princeton consortium to visualize Big Data |

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Princeton Plasma Physics Lab Eliot Feibush leads new Princeton consortium to visualize Big Data By John Greenwald April 22, 2015 Tweet Widget Google Plus One Share on Facebook Eliot Feibush (Photo by Elle Starkman/PPPL Office of Communications) Eliot Feibush Gallery: Cross section of a tokamak plasma with red and blue colors showing direction and structure of plasma flow. (Photo by PPPL) Cross section of a tokamak plasma with red and blue colors showing direction and structure of plasma

  4. Non-lead environmentally safe projectiles and explosive container

    DOE Patents [OSTI]

    Lowden, Richard A.; McCoig, Thomas M.; Dooley, Joseph B.; Smith, Cyrus M.

    1999-06-15

    A solid object having controlled frangibility, such as a bullet or a container for explosives, is made by combining two different metals in proportions calculated to achieve a desired density, without using lead. A wetting material is deposited on the base constituent which is made of a relative dense, hard material. The wetting material enhances the wettability of the base constituent with the binder constituent, which is lighter and softer than the base constituent.

  5. New Director to lead Technology Development and Commercialization division

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    | Argonne National Laboratory New Director to lead Technology Development and Commercialization division April 2, 2015 Tweet EmailPrint Suresh Sunderrajan has been appointed Director of Argonne's Technology Development and Commercialization Division (TDC), effective April 20. Sunderrajan comes to Argonne from United Technologies Corporation, where he served as Director of Innovation Business Development (IBD), the Corporate IP monetization organization. He was responsible for patent and

  6. SunShot to Lead Sessions at Solar Power International

    Office of Energy Efficiency and Renewable Energy (EERE)

    The SunShot Initiative is leading a number of educational and informational sessions at the 2016 Solar Power International conference from September 12-15 in Las Vegas. Join us as we delve into upcoming funding programs, highlight our current awardees and their innovative projects, and discuss some of the most important trends in the solar industry. See all of SunShot's events below.

  7. Non-lead environmentally safe projectiles and explosive container

    DOE Patents [OSTI]

    Lowden, R.A.; McCoig, T.M.; Dooley, J.B.; Smith, C.M.

    1999-06-15

    A solid object having controlled frangibility, such as a bullet or a container for explosives, is made by combining two different metals in proportions calculated to achieve a desired density, without using lead. A wetting material is deposited on the base constituent which is made of a relative dense, hard material. The wetting material enhances the wettability of the base constituent with the binder constituent, which is lighter and softer than the base constituent. 10 figs.

  8. Solar Test Facility Upgrades Complete, Leading to Better Sandia

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Capabilities to Support Power Industry Test Facility Upgrades Complete, Leading to Better Sandia Capabilities to Support Power Industry - Sandia Energy Energy Search Icon Sandia Home Locations Contact Us Employee Locator Energy & Climate Secure & Sustainable Energy Future Stationary Power Energy Conversion Efficiency Solar Energy Wind Energy Water Power Supercritical CO2 Geothermal Natural Gas Safety, Security & Resilience of the Energy Infrastructure Energy Storage Nuclear Power

  9. Leading the Charge: Harold Frank | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Harold Frank Leading the Charge: Harold Frank June 22, 2012 - 5:11pm Addthis Harold "Gus" Frank, Forest County Potawatomi Community Chairman and 2012 White House "Champion of Change". Photo from Potawatomi Traveling Times Harold "Gus" Frank, Forest County Potawatomi Community Chairman and 2012 White House "Champion of Change". Photo from Potawatomi Traveling Times Solar panels on the rooftop of the Forest County Potawatomi Tribe's administration building

  10. Leading the Charge: Jana Ganion Advances Blue Lake Rancheria's Climate

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Action Agenda | Department of Energy Jana Ganion Advances Blue Lake Rancheria's Climate Action Agenda Leading the Charge: Jana Ganion Advances Blue Lake Rancheria's Climate Action Agenda February 27, 2015 - 10:38am Addthis Jana Ganion is the Energy Director for the Blue Lake Rancheria. Jana Ganion is the Energy Director for the Blue Lake Rancheria. Change doesn't happen on its own. It's led by dedicated and passionate people who are committed to empowering Indian Country to energize future

  11. Leading the Charge: Jim Manion | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Jim Manion Leading the Charge: Jim Manion February 23, 2012 - 5:23pm Addthis Jim Manion, Confederated Tribes of the Warm Springs Reservation of Oregon Jim Manion, Confederated Tribes of the Warm Springs Reservation of Oregon What are the greatest energy development opportunities for Indian Country? Bring power to communities within Indian Country that currently don't have energy Create needed jobs that offer tribal members opportunities to earn incomes sufficient to support their families

  12. Leading the Charge: Tribal Women in Power | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Tribal Women in Power Leading the Charge: Tribal Women in Power October 22, 2012 - 4:19pm Addthis Andrea Alexander, Makah Tribe in Neah Bay (Washington)/Affiliated Tribes of Northwest Indians Andrea Alexander, Makah Tribe in Neah Bay (Washington)/Affiliated Tribes of Northwest Indians Kathy Mayo, Eagle Village in Upper Yukon (Alaska)/Tanana Chiefs Conference Kathy Mayo, Eagle Village in Upper Yukon (Alaska)/Tanana Chiefs Conference Tara Hess-McGeown, Washoe Tribe of Nevada and

  13. NREL Leads Energy Systems Integration, Continuum Magazine: Issue 4 (Book)

    SciTech Connect (OSTI)

    Not Available

    2013-04-01

    Continuum Magazine showcases NREL's latest and most impactful clean energy innovations. This issue, 'NREL Leads Energy Systems Integration' explores the discipline of energy systems integration, in particular the role of the laboratory's new, one-of-a-kind Energy System Integration Facility. NREL scientists, engineers, and analysts deeply understand the fundamental science and technologies underpinning major energy producing and consuming systems, as well as the transmission infrastructure and communications and data networks required to integrate energy systems at all scales.

  14. Acid-functionalized polyolefin materials and their use in acid-promoted chemical reactions

    DOE Patents [OSTI]

    Oyola, Yatsandra; Tian, Chengcheng; Bauer, John Christopher; Dai, Sheng

    2016-06-07

    An acid-functionalized polyolefin material that can be used as an acid catalyst in a wide range of acid-promoted chemical reactions, wherein the acid-functionalized polyolefin material includes a polyolefin backbone on which acid groups are appended. Also described is a method for the preparation of the acid catalyst in which a precursor polyolefin is subjected to ionizing radiation (e.g., electron beam irradiation) of sufficient power and the irradiated precursor polyolefin reacted with at least one vinyl monomer having an acid group thereon. Further described is a method for conducting an acid-promoted chemical reaction, wherein an acid-reactive organic precursor is contacted in liquid form with a solid heterogeneous acid catalyst comprising a polyolefin backbone of at least 1 micron in one dimension and having carboxylic acid groups and either sulfonic acid or phosphoric acid groups appended thereto.

  15. Leading twist nuclear shadowing phenomena in hard processes with nuclei

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    L. Franfurt; Guzey, V.; Strikman, M.

    2012-01-08

    We present and discuss the theory and phenomenology of the leading twist theory of nuclear shadowing which is based on the combination of the generalization of Gribov-Glauber theory, QCD factorization theorems, and HERA QCD analysis of diffraction in lepton-proton deep inelastic scattering (DIS). We apply this technique for the analysis of a wide range of hard processes with nuclei-inclusive DIS on deuterons, medium-range and heavy nuclei, coherent and incoherent diffractive DIS with nuclei, and hard diffraction in proton-nucleus scattering - and make predictions for the effect of nuclear shadowing in the corresponding sea quark and gluon parton distributions. We alsomore » analyze the role of the leading twist nuclear shadowing in generalized parton distributions in nuclei and certain characteristics of final states in nuclear DIS. We discuss the limits of applicability of the leading twist approximation for small x scattering off nuclei and the onset of the black disk regime and methods of detecting it. It will be possible to check many of our predictions in the near future in the studies of the ultraperipheral collisions at the Large Hadron Collider (LHC). Further checks will be possible in pA collisions at the LHC and forward hadron production at Relativistic Heavy Ion Collider (RHIC). As a result, detailed tests will be possible at an Electon-Ion Collider (EIC) in USA and at the Large Hadron-Electron Collider (LHeC) at CERN.« less

  16. Maxima of two random walks: Universal statistics of lead changes

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Ben-Naim, E.; Krapivsky, P. L.; Randon-Furling, J.

    2016-04-18

    In this study, we investigate statistics of lead changes of the maxima of two discrete-time random walks in one dimension. We show that the average number of lead changes grows asmore » $${\\pi }^{-1}\\mathrm{ln}t$$ in the long-time limit. We present theoretical and numerical evidence that this asymptotic behavior is universal. Specifically, this behavior is independent of the jump distribution: the same asymptotic underlies standard Brownian motion and symmetric Lévy flights. We also show that the probability to have at most n lead changes behaves as $${t}^{-1/4}{(\\mathrm{ln}t)}^{n}$$ for Brownian motion and as $${t}^{-\\beta (\\mu )}{(\\mathrm{ln}t)}^{n}$$ for symmetric Lévy flights with index μ. The decay exponent $$\\beta \\equiv \\beta (\\mu )$$ varies continuously with the Lévy index when $$0\\lt \\mu \\lt 2$$, and remains constant $$\\beta =1/4$$ for $$\\mu \\gt 2$$.« less

  17. Leading twist nuclear shadowing phenomena in hard processes with nuclei

    SciTech Connect (OSTI)

    Leonid Frankfurt, Vadim Guzey, Mark Strikman

    2012-03-01

    We present and discuss the theory and phenomenology of the leading twist theory of nuclear shadowing which is based on the combination of the generalization of Gribov-Glauber theory, QCD factorization theorems, and HERA QCD analysis of diffraction in lepton-proton deep inelastic scattering (DIS). We apply this technique for the analysis of a wide range of hard processes with nuclei-inclusive DIS on deuterons, medium-range and heavy nuclei, coherent and incoherent diffractive DIS with nuclei, and hard diffraction in proton-nucleus scattering - and make predictions for the effect of nuclear shadowing in the corresponding sea quark and gluon parton distributions. We also analyze the role of the leading twist nuclear shadowing in generalized parton distributions in nuclei and certain characteristics of final states in nuclear DIS. We discuss the limits of applicability of the leading twist approximation for small x scattering off nuclei and the onset of the black disk regime and methods of detecting it. It will be possible to check many of our predictions in the near future in the studies of the ultraperipheral collisions at the Large Hadron Collider (LHC). Further checks will be possible in pA collisions at the LHC and forward hadron production at Relativistic Heavy Ion Collider (RHIC). Detailed tests will be possible at an Electon-Ion Collider (EIC) in USA and at the Large Hadron-Electron Collider (LHeC) at CERN.

  18. MOX Lead Assembly Fabrication at the Savannah River Site

    SciTech Connect (OSTI)

    Geddes, R.L.; Spiker, D.L.; Poon, A.P.

    1997-12-01

    The U. S. Department of Energy (DOE) announced its intent to prepare an Environmental Impact Statement (EIS) under the National Environmental Policy Act (NEPA) on the disposition of the nations weapon-usable surplus plutonium.This EIS is tiered from the Storage and Disposition of Weapons-Usable Fissile Material Programmatic Environmental Impact Statement issued in December 1996,and the associated Record of Decision issued on January, 1997. The EIS will examine reasonable alternatives and potential environmental impacts for the proposed siting, construction, and operation of three types of facilities for plutonium disposition. The three types of facilities are: a pit disassembly and conversion facility, a facility to immobilize surplus plutonium in a glass or ceramic form for disposition, and a facility to fabricate plutonium oxide into mixed oxide (MOX) fuel.As an integral part of the surplus plutonium program, Oak Ridge National Laboratory (ORNL) was tasked by the DOE Office of Fissile Material Disposition(MD) as the technical lead to organize and evaluate existing facilities in the DOE complex which may meet MD`s need for a domestic MOX fuel fabrication demonstration facility. The Lead Assembly (LA) facility is to produce 1 MT of usable test fuel per year for three years. The Savannah River Site (SRS) as the only operating plutonium processing site in the DOE complex, proposes two options to carry out the fabrication of MOX fuel lead test assemblies: an all Category I facility option and a combined Category I and non-Category I facilities option.

  19. Renewable energy and utility regulation

    SciTech Connect (OSTI)

    Not Available

    1991-04-10

    This report summarizes the results of a joint project on renewable energy of the National Association of Regulatory Utility Commissioners (NARUC) and the US DOE. NARUC'S Task Force on Renewable Energy conducted a review of the current state of renewable energy technologies to evaluate their potential and extract key policy lessons from experience already gained in deployment of these technologies in numerous states. The main focus of this effort has been to clarify how utility regulators affect the development of renewable energy resources. The goal of the project was twofold: (1) identify the factors that have led to success or failure or renewable energy technologies in various energy markets, and (2) to develop an agenda on renewable energy and utility regulation for NARUC and the DOE. This report consists of three sections: renewable energy contributions, costs and potential; factors affecting development of renewable energy resources; and a renewable energy agenda for NARUC.

  20. Renewable energy and utility regulation

    SciTech Connect (OSTI)

    Not Available

    1991-04-10

    This report summarizes the results of a joint project on renewable energy of the National Association of Regulatory Utility Commissioners (NARUC) and the US DOE. NARUC`S Task Force on Renewable Energy conducted a review of the current state of renewable energy technologies to evaluate their potential and extract key policy lessons from experience already gained in deployment of these technologies in numerous states. The main focus of this effort has been to clarify how utility regulators affect the development of renewable energy resources. The goal of the project was twofold: (1) identify the factors that have led to success or failure or renewable energy technologies in various energy markets, and (2) to develop an agenda on renewable energy and utility regulation for NARUC and the DOE. This report consists of three sections: renewable energy contributions, costs and potential; factors affecting development of renewable energy resources; and a renewable energy agenda for NARUC.