National Library of Energy BETA

Sample records for regulated lead acid

  1. DOE specification: Valve-regulated type lead-acid storage batteries

    SciTech Connect (OSTI)

    1996-08-01

    This document contains a ``fill-in-the-blanks`` guide specification for procurement of sealed valve-regulated type lead-acid storage batteries, for uninterruptible power supply applications.

  2. DOE-SPEC-3019-96; Valve-Regulated Type Lead-Acid Storage Batteries

    Office of Environmental Management (EM)

    9-96 August 1996 DOE SPECIFICATION VALVE-REGULATED TYPE LEAD-ACID STORAGE BATTERIES U.S. Department of Energy FSC 6140 Washington, D.C. 20585 DISTRIBUTION STATEMENT A. Approved for public release; distribution is unlimited. This document has been reproduced directly from the best available copy. Available to DOE and DOE contractors from the Office of Scientific and Technical Information, P.O. Box 62, Oak Ridge, TN 37831; (423) 576-8401. Available to the public from the U.S. Department of

  3. Sandia National Laboratories: Due Diligence on Lead Acid Battery...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Due Diligence on Lead Acid Battery Recycling March 23, 2011 Lead Acid Batteries on secondary containment pallet Lead Acid Batteries on secondary containment pallet In 2004, the US...

  4. Primer on lead-acid storage batteries

    SciTech Connect (OSTI)

    1995-09-01

    This handbook was developed to help DOE facility contractors prevent accidents caused during operation and maintenance of lead-acid storage batteries. Major types of lead-acid storage batteries are discussed as well as their operation, application, selection, maintenance, and disposal (storage, transportation, as well). Safety hazards and precautions are discussed in the section on battery maintenance. References to industry standards are included for selection, maintenance, and disposal.

  5. Lightweight, durable lead-acid batteries

    DOE Patents [OSTI]

    Lara-Curzio, Edgar; An, Ke; Kiggans, Jr., James O; Dudney, Nancy J; Contescu, Cristian I; Baker, Frederick S; Armstrong, Beth L

    2013-05-21

    A lightweight, durable lead-acid battery is disclosed. Alternative electrode materials and configurations are used to reduce weight, to increase material utilization and to extend service life. The electrode can include a current collector having a buffer layer in contact with the current collector and an electrochemically active material in contact with the buffer layer. In one form, the buffer layer includes a carbide, and the current collector includes carbon fibers having the buffer layer. The buffer layer can include a carbide and/or a noble metal selected from of gold, silver, tantalum, platinum, palladium and rhodium. When the electrode is to be used in a lead-acid battery, the electrochemically active material is selected from metallic lead (for a negative electrode) or lead peroxide (for a positive electrode).

  6. Lightweight, durable lead-acid batteries

    DOE Patents [OSTI]

    Lara-Curzio, Edgar; An, Ke; Kiggans, Jr., James O.; Dudney, Nancy J.; Contescu, Cristian I.; Baker, Frederick S.; Armstrong, Beth L.

    2011-09-13

    A lightweight, durable lead-acid battery is disclosed. Alternative electrode materials and configurations are used to reduce weight, to increase material utilization and to extend service life. The electrode can include a current collector having a buffer layer in contact with the current collector and an electrochemically active material in contact with the buffer layer. In one form, the buffer layer includes a carbide, and the current collector includes carbon fibers having the buffer layer. The buffer layer can include a carbide and/or a noble metal selected from of gold, silver, tantalum, platinum, palladium and rhodium. When the electrode is to be used in a lead-acid battery, the electrochemically active material is selected from metallic lead (for a negative electrode) or lead peroxide (for a positive electrode).

  7. Advanced Lead Acid Battery Consortium | Open Energy Information

    Open Energy Info (EERE)

    Lead Acid Battery Consortium Jump to: navigation, search Name: Advanced Lead-Acid Battery Consortium Place: Durham, North Carolina Zip: 27713 Sector: Vehicles Product: The ALABC is...

  8. Closure device for lead-acid batteries

    DOE Patents [OSTI]

    Ledjeff, Konstantin (Schwalbach, DE)

    1983-01-01

    A closure device for lead-acid batteries includes a filter of granulated activated carbon treated to be hydrophobic combined with means for preventing explosion of emitted hydrogen and oxygen gas. The explosion prevention means includes a vertical open-end tube within the closure housing for maintaining a liquid level above side wall openings in an adjacent closed end tube. Gases vent from the battery through a nozzle directed inside the closed end tube against an impingement surface to remove acid droplets. The gases then flow through the side wall openings and the liquid level to quench any possible ignition prior to entering the activated carbon filter. A wick in the activated carbon filter conducts condensed liquid back to the closure housing to replenish the liquid level limited by the open-end tube.

  9. Sandia National Laboratories: Due Diligence on Lead Acid Battery Recycling

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Due Diligence on Lead Acid Battery Recycling March 23, 2011 Lead Acid Batteries on secondary containment pallet Lead Acid Batteries on secondary containment pallet In 2004, the US Geological Survey estimated that 95% of lead in the United States is recycled, primarily from used lead acid batteries. A broader 2009 European study estimated that globally about 52% of lead is recycled, and a 2008 Asian study estimated a global recycle rate of 68%. Unfortunately, many incidents over the past decade

  10. DOE specification: Flooded-type lead-acid storage batteries

    SciTech Connect (OSTI)

    1996-08-01

    This document contains a ``fill-in-the-blanks`` guide specification for procurement of flooded-type lead-acid storage batteries, for uninterruptible power supply applications.

  11. Anaerobic microbial dissolution of lead and production of organic acids

    DOE Patents [OSTI]

    Francis, A.J.; Dodge, C.; Chendrayan, K.; Quinby, H.L.

    1987-04-16

    The present invention related to an anaerobic bacterial culture of Clostridium sp. ATCC No. 53464 which solubilizes lead oxide under anaerobic conditions in coal and industrial wastes and therefore presents a method of removing lead from such wastes before they are dumped into the environment. The rat of lead dissolution during logarithmic growth of the bacteria in 40 ml medium containing 3.32 ..mu..moles of lead as lead oxide was 0.042 ..mu..moles m1/sup /-/1/ hr/sup /-/1/. Dissolution of lead oxide by the bacterial isolate is due to the production of metabolites and acidity in the culture medium. The major metabolites are acetic, butyric and lactic acid. The major metabolites are acetic, butyric and lactic acid. Clostridium sp. ATCC No. 53464 can be used in the recovery of the strategic metals from ores and wastes and also for the production of lactic acid for commercial purposes. The process yields large quantities of lactic acid as well as lead complexed in a stable form with said acids. 4 figs., 3 tabs.

  12. Anaerobic microbial dissolution of lead and production of organic acids

    DOE Patents [OSTI]

    Francis, Arokiasamy J. (Middle Island, NY); Dodge, Cleveland (Wading River, NY); Chendrayan, Krishnachetty (Coimbatore Tamil Nadu, IN); Quinby, Helen L. (Cambridge, MD)

    1988-01-01

    The present invention relates to an anaerobic bacterial culture of Clostridium sp. ATCC No. 53464 which solubilizes lead oxide under anaerobic conditions in coal and industrial wastes and therefore presents a method of removing lead from such wastes before they are dumped into the environment. The rate of lead dissolution during logarithmic growth of the bacteria in 40 ml medium containing 3.32 .mu.moles of lead as lead oxide was 0.042 .mu.moles ml.sup.-1 hr.sup.-1. Dissolution of lead oxide by the bacterial isolate is due to the production of metabolites and acidity in the culture medium. The major metabolites are acetic, butyric and lactic acid. Clostridium sp. ATCC No. 53464 can be used in the recovery of strategic metals from ores and wastes and also for the production of lactic acid for commercial purposes. The process yields large quantities of lactic acid as well as lead complexed in a stable form with said acids.

  13. System for agitating the acid in a lead-acid battery

    DOE Patents [OSTI]

    Weintraub, Alvin (Schenectady, NY); MacCormack, Robert S. (Glenville, NY)

    1987-01-01

    A system and method for agitating the acid in a large lead-sulfuric acid storage battery of the calcium type. An air-lift is utilized to provide the agitation. The air fed to the air-lift is humidified prior to being delivered to the air-lift.

  14. Regulating for the long term: SMCRA and acid mine drainage

    SciTech Connect (OSTI)

    Shea, C.W.

    1995-12-31

    With the passage of the Surface Mining Control and Reclamation Act of 1977 (SMCRA), regulators and industry representatives expected to solve the problem of pollution of the Nation`s waterways caused by acidic discharges from coal mines. Eighteen years after the passage of SMCRA, hard issues of predicting, regulating and treating acid mine drainage remain. Acid mine drainage is most common in the coal seams of the Midwest and Appalachia: Pennsylvania, West Virginia, Maryland, Ohio, Illinois, and Tennessee. This article discusses regulation of coal mines and acid mine drainage for the long term.

  15. Anaerobic microbial dissolution of lead and production of organic acids

    DOE Patents [OSTI]

    Francis, A.J.; Dodge, C.; Chendrayan, K.

    1986-02-28

    The present invention relates to a method of solubilizing lead, in the form of lead oxide, found in industrial wastes, before these wastes are dumped into the environment. The lead is solubilized by dissolving the lead oxide in the wastes through contact with an anaerobic bacterial culture containing the bacterium ATCC No. 53464. The solubilized lead can then be removed from the wastes by chemical separation. It could also be removed by extending the contact period with the bacterial culture. As the culture grows, the solubilized lead is removed from the wastes by bioaccumulation by the microorganism or by immobilization by a polymer-like material produced by the microorganism. At this point, the lead is then removed from the wastes when the waste material is separated from the bacterial culture. If desired, the bacterial culture could be digested at this point to yield relatively pure lead for further industrial use.

  16. Mutations in global regulators lead to metabolic selection during adaptation to complex environments

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Saxer, Gerda; Krepps, Michael D.; Merkley, Eric D.; Ansong, Charles; Deatherage Kaiser, Brooke L.; Valovska, Marie -Thérèse; Ristic, Nikola; Yeh, Ping T.; Prakash, Vittal P.; Leiser, Owen P.; et al

    2014-12-11

    Adaptation to ecologically complex environments can provide insights into the evolutionary dynamics and functional constraints encountered by organisms during natural selection. Unlike adaptation to a single limiting resource, adaptation to a new environment with abundant and varied resources can be difficult to achieve by small incremental changes since many mutations are required to achieve even modest gains in fitness. Since changing complex environments are quite common in nature, we investigated how such an epistatic bottleneck can be avoided to allow rapid adaptation. We show that adaptive mutations arise repeatedly in independently evolved populations in the context of greatly increased geneticmore » and phenotypic diversity. We go on to show that weak selection requiring substantial metabolic reprogramming can be readily achieved by mutations in the global response regulator arcA and the stress response regulator rpoS. We identified 46 unique single-nucleotide variants of arcA and 18 mutations in rpoS, nine of which resulted in stop codons or large deletions, suggesting that a subtle modulation of ArcA function and knockouts of rpoS are largely responsible for the metabolic shifts leading to adaptation. These mutations allow a higher order “metabolic selection” that eliminates epistatic bottlenecks, which could occur when many changes would be required. Proteomic and carbohydrate analysis of adapting E. coli populations revealed an up-regulation of enzymes associated with the TCA cycle and amino acid metabolism and an increase in the secretion of putrescine. The overall effect of adaptation across populations is to redirect and efficiently utilize uptake and catabolism of abundant amino acids. Concomitantly, there is a pronounced spread of more ecologically limited strains that results from specialization through metabolic erosion. Remarkably, the global regulators arcA and rpoS can provide a “one-step” mechanism of adaptation to a novel environment, which highlights the importance of global resource management as a powerful strategy to adaptation.« less

  17. Fact Sheet: Carbon-Enhanced Lead-Acid Batteries (October 2012)

    Office of Environmental Management (EM)

    Lead-acid batteries are currently used in a variety of applications, ranging from automotive starting batteries to storage for renewable energy sources. Lead-acid batteries form deposits on the negative electrodes that hinder their performance, which is a major hurdle to the wider use of lead-acid batteries for grid-scale energy storage. The formation of deposits is exacerbated under the operating conditions required by many large-scale energy storage systems, which cycle at a high electrical

  18. Mutations in global regulators lead to metabolic selection during adaptation to complex environments

    SciTech Connect (OSTI)

    Saxer, Gerda; Krepps, Michael D.; Merkley, Eric D.; Ansong, Charles; Deatherage Kaiser, Brooke L.; Valovska, Marie -Thrse; Ristic, Nikola; Yeh, Ping T.; Prakash, Vittal P.; Leiser, Owen P.; Nakhleh, Luay; Gibbons, Henry S.; Kreuzer, Helen W.; Shamoo, Yousif; Matic, Ivan

    2014-12-11

    Adaptation to ecologically complex environments can provide insights into the evolutionary dynamics and functional constraints encountered by organisms during natural selection. Unlike adaptation to a single limiting resource, adaptation to a new environment with abundant and varied resources can be difficult to achieve by small incremental changes since many mutations are required to achieve even modest gains in fitness. Since changing complex environments are quite common in nature, we investigated how such an epistatic bottleneck can be avoided to allow rapid adaptation. We show that adaptive mutations arise repeatedly in independently evolved populations in the context of greatly increased genetic and phenotypic diversity. We go on to show that weak selection requiring substantial metabolic reprogramming can be readily achieved by mutations in the global response regulator arcA and the stress response regulator rpoS. We identified 46 unique single-nucleotide variants of arcA and 18 mutations in rpoS, nine of which resulted in stop codons or large deletions, suggesting that a subtle modulation of ArcA function and knockouts of rpoS are largely responsible for the metabolic shifts leading to adaptation. These mutations allow a higher order metabolic selection that eliminates epistatic bottlenecks, which could occur when many changes would be required. Proteomic and carbohydrate analysis of adapting E. coli populations revealed an up-regulation of enzymes associated with the TCA cycle and amino acid metabolism and an increase in the secretion of putrescine. The overall effect of adaptation across populations is to redirect and efficiently utilize uptake and catabolism of abundant amino acids. Concomitantly, there is a pronounced spread of more ecologically limited strains that results from specialization through metabolic erosion. Remarkably, the global regulators arcA and rpoS can provide a one-step mechanism of adaptation to a novel environment, which highlights the importance of global resource management as a powerful strategy to adaptation.

  19. Fact Sheet: Carbon-Enhanced Lead-Acid Batteries (October 2012)

    Broader source: Energy.gov [DOE]

    DOE's Energy Storage Program is funding research and testing to improve the performance and reduce the cost of lead-acid batteries. Research to understand and quantify the mechanisms responsible...

  20. Lead-based paint and lead-containing materials: The impact of recent EPA and OSHA regulations on maintenance and construction

    SciTech Connect (OSTI)

    Staker, R.D.; Scheffius, F.R.

    1998-07-01

    Over the past several years a number of new federal environmental, health, and safety regulations have been established which address various types of lead containing materials such as lead used in solder and lead-based paint. The regulations pertain to the use, removal, disposal, and handling of lead-containing materials during maintenance activities, renovation activities, and new construction. This paper will present a review of these new regulations, the impact on and applicability to maintenance and construction activities, and the risks to human health and environment. Examples will be used to illustrate the concepts discussed. This paper should be of particular interest to electric power senior managers, plant managers, environmental managers, and environmental staff.

  1. A Study of Lead-Acid Battery Efficiency Near Top-of-Charge

    Office of Scientific and Technical Information (OSTI)

    Lead-Acid Battery Efficiency Near Top-of-Charge and the Impact on PV System Design John W. Stevens and Garth P. Corey Sandia National Laboratories, Photovoltaic System Applications Department Sandia National Laboratories, Battery Analysis and Evaluation Department PO Box 5800, MS 0753 Albuquerque, New Mexico 87185-0753 ABSTRACT discharge and PV array size. Hence, a procedure has been developed, and is described herein, to acquire these efficiency versus SOC measurements. Preliminary results

  2. DOE-HDBK-1084-95; Primer on Lead-Acid Storage Batteries

    Office of Environmental Management (EM)

    HDBK-1084-95 September 1995 DOE HANDBOOK PRIMER ON LEAD-ACID STORAGE BATTERIES U.S. Department of Energy FSC-6910 Washington, D.C. 20585 DISTRIBUTION STATEMENT A. Approved for public release; distribution is unlimited. DISCLAIMER This report was prepared as an account of work sponsored by an agency of the United States Government. Neither the United States Government nor any agency thereof, nor any of their employees, makes any warranty, express or implies, or assumes any legal liability or

  3. DOE-SPEC-3018-96; Flooded-Type Lead-Acid Storage Batteries

    Office of Environmental Management (EM)

    8-96 August 1996 DOE SPECIFICATION FLOODED-TYPE LEAD-ACID STORAGE BATTERIES U.S. Department of Energy FSC 6140 Washington, D.C. 20585 DISTRIBUTION STATEMENT A. Approved for public release; distribution is unlimited. This document has been reproduced directly from the best available copy. Available to DOE and DOE contractors from the Office of Scientific and Technical Information, P.O. Box 62, Oak Ridge, TN 37831; (423) 576-8401. Available to the public from the U.S. Department of Commerce,

  4. AVTA: 2010 Honda Civic HEV with Experimental Ultra Lead Acid Battery Testing Results

    Broader source: Energy.gov [DOE]

    The Vehicle Technologies Office's Advanced Vehicle Testing Activity carries out testing on a wide range of advanced vehicles and technologies on dynamometers, closed test tracks, and on-the-road. These results provide benchmark data that researchers can use to develop technology models and guide future research and development. The following reports describe results of testing done on a 2010 Civic hybrid electric vehicle with an advanced experimental ultra-lead acid battery, an experimental vehicle not for sale. The baseline performance testing provides a point of comparison for the other test results. Taken together, these reports give an overall view of how this vehicle functions under extensive testing. This research was conducted by Idaho National Laboratory.

  5. Epidemiological-environemental study of lead acid battery workers. III. Chronic effects of sulfuric acid on the respiratory system and teeth

    SciTech Connect (OSTI)

    Gamble, J.; Jones, W.; Hancock, J.; Meckstroth, R.L.

    1984-10-01

    The effects of long-term exposure to sulfuric acid mist on the teeth and respiratory system were studied in 248 workers in five plants manufacturing lead acid batteries. The prevalence of cough, phlegm, dyspnea, and wheezing as determined by questionnaire were not associated with estimates of cumulative acid exposure. There was only one case of irregular opacities seen on the chest radiographs. There was no statistically significant association of reduced FEV/sub 1/ peak flow, FEF/sub 50/, and FEF/sub 75/ with acid exposure although the higher exposed group had lower mean values. FVC in the high exposure group showed a statistically significant reductioon compared to the low exposure group but there was no significant association when exposure was analyzed as a continuous variable. The ratio of observed to expected prevalence of teeth etching and erosion was about four times greater in the high acid-exposure group. The earliest case of etching occured after 4 months exposure to an estimated average exposure of 0.23 mg/m/sup 3/ sulfuric acid.

  6. Leading trends in environmental regulation that affect energy development. Final report

    SciTech Connect (OSTI)

    Steele, R V; Attaway, L D; Christerson, J A; Kikel, D A; Kuebler, J D; Lupatkin, B M; Liu, C S; Meyer, R; Peyton, T O; Sussin, M H

    1980-01-01

    Major environmental issues that are likely to affect the implementation of energy technologies between now and the year 2000 are identified and assessed. The energy technologies specifically addressed are: oil recovery and processing; gas recovery and processing; coal liquefaction; coal gasification (surface); in situ coal gasification; direct coal combustion; advanced power systems; magnetohydrodynamics; surface oil shale retorting; true and modified in situ oil shale retorting; geothermal energy; biomass energy conversion; and nuclear power (fission). Environmental analyses of these technologies included, in addition to the main processing steps, the complete fuel cycle from resource extraction to end use. A comprehensive survey of the environmental community (including environmental groups, researchers, and regulatory agencies) was carried out in parallel with an analysis of the technologies to identify important future environmental issues. Each of the final 20 issues selected by the project staff has the following common attributes: consensus of the environmental community that the issue is important; it is a likely candidate for future regulatory action; it deals with a major environmental aspect of energy development. The analyses of the 20 major issues address their environmental problem areas, current regulatory status, and the impact of future regulations. These analyses are followed by a quantitative assessment of the impact on energy costs and nationwide pollutant emissions of possible future regulations. This is accomplished by employing the Strategic Environmental Assessment System (SEAS) for a subset of the 20 major issues. The report concludes with a more general discussion of the impact of environmental regulatory action on energy development.

  7. Fetal and neonatal exposure to nicotine leads to augmented hepatic and circulating triglycerides in adult male offspring due to increased expression of fatty acid synthase

    SciTech Connect (OSTI)

    Ma, Noelle; Nicholson, Catherine J.; Wong, Michael; Holloway, Alison C.; Hardy, Daniel B.

    2014-02-15

    While nicotine replacement therapy is assumed to be a safer alternative to smoking during pregnancy, the long-term consequences for the offspring remain elusive. Animal studies now suggest that maternal nicotine exposure during perinatal life leads to a wide range of adverse outcomes for the offspring including increased adiposity. The focus of this study was to investigate if nicotine exposure during pregnancy and lactation leads to alterations in hepatic triglyceride synthesis. Female Wistar rats were randomly assigned to receive daily subcutaneous injections of saline (vehicle) or nicotine bitartrate (1 mg/kg/day) for two weeks prior to mating until weaning. At postnatal day 180 (PND 180), nicotine exposed offspring exhibited significantly elevated levels of circulating and hepatic triglycerides in the male offspring. This was concomitant with increased expression of fatty acid synthase (FAS), the critical hepatic enzyme in de novo triglyceride synthesis. Given that FAS is regulated by the nuclear receptor Liver X receptor (LXR?), we measured LXR? expression in both control and nicotine-exposed offspring. Nicotine exposure during pregnancy and lactation led to an increase in hepatic LXR? protein expression and enriched binding to the putative LXRE element on the FAS promoter in PND 180 male offspring. This was also associated with significantly enhanced acetylation of histone H3 [K9,14] surrounding the FAS promoter, a hallmark of chromatin activation. Collectively, these findings suggest that nicotine exposure during pregnancy and lactation leads to an increase in circulating and hepatic triglycerides long-term via changes in the transcriptional and epigenetic regulation of the hepatic lipogenic pathway. - Highlights: Our data reveals the links nicotine exposure in utero and long-term hypertriglyceridemia. It is due to nicotine-induced augmented expression of hepatic FAS and LXR? activity. Moreover, this involves nicotine-induced enhanced acetylation of histone H3 [K9,14]. This provides a mechanism for developmental origins of health and disease (DOHaD)

  8. Crystal Structures of the Reduced, Sulfenic Acid, and Mixed Disulfide Forms of SarZ, a Redox Active Global Regulator in Staphylococcus aureus

    SciTech Connect (OSTI)

    Poor, Catherine B.; Chen, Peng R.; Duguid, Erica; Rice, Phoebe A.; He, Chuan

    2010-01-20

    SarZ is a global transcriptional regulator that uses a single cysteine residue, Cys{sup 13}, to sense peroxide stress and control metabolic switching and virulence in Staphylococcus aureus. SarZ belongs to the single-cysteine class of OhrR-MgrA proteins that play key roles in oxidative resistance and virulence regulation in various bacteria. We present the crystal structures of the reduced form, sulfenic acid form, and mixed disulfide form of SarZ. Both the sulfenic acid and mixed disulfide forms are structurally characterized for the first time for this class of proteins. The Cys{sup 13} sulfenic acid modification is stabilized through two hydrogen bonds with surrounding residues, and the overall DNA-binding conformation is retained. A further reaction of the Cys{sup 13} sulfenic acid with an external thiol leads to formation of a mixed disulfide bond, which results in an allosteric change in the DNA-binding domains, disrupting DNA binding. Thus, the crystal structures of SarZ in three different states provide molecular level pictures delineating the mechanism by which this class of redox active regulators undergoes activation. These structures help to understand redox-mediated virulence regulation in S. aureus and activation of the MarR family proteins in general.

  9. July 24, 2009, Visiting Speakers Program Panel Discussion - Governance and Regulations: U. S. to Lead or Lag in the 21st Century - Companion Book

    Office of Environmental Management (EM)

    Hosted by the U.S. Department of Energy Office of Health, Safety and Security and the National Academy of Public Administration July 24, 2009 Washington, DC Governance and Regulation: U.S. to Lead or Lag in the 21 st Century Visiting Speakers Program Event The National Academy of Public Administration is a non-profit, independent coalition of top public management and organizational leaders who tackle the nation's most critical and complex challenges. With a network of more than 600

  10. Down-regulation of the Caffeic acid O-methyltransferase Gene in Switchgrass Reveals a Novel Monolignol Analog

    SciTech Connect (OSTI)

    Tschaplinski, Timothy J; Standaert, Robert F; Engle, Nancy L; Martin, Madhavi Z; Sangha, Amandeep K; Parks, Jerry M; Smith, Jeremy C; Samuel, Reichel; Pu, Yunqiao; Ragauskas, A J; Hamilton, Choo Yieng; Fu, Chunxiang; Wang, Zeng-Yu; Davison, Brian H; Dixon, Richard A; Mielenz, Jonathan R

    2012-01-01

    Down-regulation of the caffeic acid 3-O-methyltransferase (COMT) gene in the lignin biosynthetic pathway of switchgrass (Panicum virgatum) resulted in cell walls of transgenic plants releasing more constituent sugars after pretreatment by dilute acid and treatment with glycosyl hydrolases from an added enzyme preparation and from Clostridium thermocellum. Fermentation of both wild-type and transgenic switchgrass after milder hot water pretreatment with no water washing showed that only the transgenic switchgrass inhibited C. thermocellum. Gas chromatography-mass spectrometry-based metabolomics were undertaken on cell wall aqueous extracts to determine the nature of the microbial inhibitors, confirming the increased concentration of a number of phenolic acids and aldehydes that are known inhibitors of fermentation. Metabolomic analyses of the transgenic biomass additionally revealed the presence of a novel monolignol-like metabolite, identified as trans-3, 4-dimethoxy-5-hydroxycinnamyl alcohol (iso-sinapyl alcohol) in both non-pretreated, as well as hot water pretreated samples. Although there was no indication that iso-sinapyl alcohol was integrated into the cell wall, diversion of substrates from sinapyl alcohol to free iso-sinapyl alcohol, its glucoside, and associated upstream lignin pathway changes, including increased phenolic aldehydes and acids, are associated with more facile cell wall deconstruction, and to the observed inhibitory effect on microbial growth.

  11. Down-regulation of gibberellic acid in poplar has negligible effects on host-plant suitability and insect pest response

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Buhl, Christine; Strauss, Steven H.; Lindroth, Richard L.

    2015-01-06

    Abstract Endogenous levels and signaling of gibberellin plant hormones such as gibberellic acid (GA) have been genetically down-regulated to create semi-dwarf varieties of poplar. The potential benefits of semi-dwarf stature include reduced risk of wind damage, improved stress tolerance, and improved wood quality. Despite these benefits, modification of growth traits may have consequences for non-target traits that confer defense against insect herbivores. According to the growth-differentiation balance hypothesis, reductions in growth may shift allocation of carbon from growth to chemical resistance traits, thereby altering plant defense. To date, host-plant suitability and pest response have not been comprehensively evaluated in GAmore » down-regulated plants. We quantified chemical resistance and nitrogen (an index of protein) in GA down-regulated and wild-type poplar (Populus alba × P. tremula) genotypes. We also evaluated performance of both generalist (Lymantria dispar) and specialist (Chrysomela scripta) insect pests reared on these genotypes. Our evaluation of resistance traits in four GA down-regulated genotypes revealed increased phenolic glycosides in one modified genotype and reduced lignin in two modified genotypes relative to the non-transgenic wild type. Nitrogen levels did not vary significantly among the experimental genotypes. Generalists reared on the four GA down-regulated genotypes exhibited reduced performance on only one modified genotype relative to the wild type. Specialists, however, performed similarly across all genotypes. Results from this study indicate that although some non-target traits varied among GA down-regulated genotypes, the differences in poplar pest susceptibility were modest and highly genotype-specific.« less

  12. Down-regulation of gibberellic acid in poplar has negligible effects on host-plant suitability and insect pest response

    SciTech Connect (OSTI)

    Buhl, Christine; Strauss, Steven H.; Lindroth, Richard L.

    2015-01-06

    Abstract Endogenous levels and signaling of gibberellin plant hormones such as gibberellic acid (GA) have been genetically down-regulated to create semi-dwarf varieties of poplar. The potential benefits of semi-dwarf stature include reduced risk of wind damage, improved stress tolerance, and improved wood quality. Despite these benefits, modification of growth traits may have consequences for non-target traits that confer defense against insect herbivores. According to the growth-differentiation balance hypothesis, reductions in growth may shift allocation of carbon from growth to chemical resistance traits, thereby altering plant defense. To date, host-plant suitability and pest response have not been comprehensively evaluated in GA down-regulated plants. We quantified chemical resistance and nitrogen (an index of protein) in GA down-regulated and wild-type poplar (Populus alba P. tremula) genotypes. We also evaluated performance of both generalist (Lymantria dispar) and specialist (Chrysomela scripta) insect pests reared on these genotypes. Our evaluation of resistance traits in four GA down-regulated genotypes revealed increased phenolic glycosides in one modified genotype and reduced lignin in two modified genotypes relative to the non-transgenic wild type. Nitrogen levels did not vary significantly among the experimental genotypes. Generalists reared on the four GA down-regulated genotypes exhibited reduced performance on only one modified genotype relative to the wild type. Specialists, however, performed similarly across all genotypes. Results from this study indicate that although some non-target traits varied among GA down-regulated genotypes, the differences in poplar pest susceptibility were modest and highly genotype-specific.

  13. Standard operating procedure for the laboratory analysis of lead in paint, bulk dust, and soil by ultrasonic, acid digestion and inductively coupled plasma emission spectrometric measurement

    SciTech Connect (OSTI)

    Grohse, P.M.; Gutknecht, W.F.; Luk, K.K.; Wilson, B.M.; Van Hise, C.C.

    1997-09-01

    The details and performance of a simplified extraction procedure and analysis for three media are provided. Paint, bulk dust, and soil are collected using standard or referenced methods. Up to 0.25 g of paint, bulk dust, or soil weighted out and placed in a 50-mL centrifuge tube. Five mL of 25% (v/v) nitric acid is added and the sample is ultrasonicated for 30 minutes.

  14. Accumulated SET protein up-regulates and interacts with hnRNPK, increasing its binding to nucleic acids, the Bcl-xS repression, and cellular proliferation

    SciTech Connect (OSTI)

    Almeida, Luciana O.; Garcia, Cristiana B.; Matos-Silva, Flavia A.; Curti, Carlos; Leopoldino, Andria M.

    2014-02-28

    Highlights: hnRNPK is a new target of SET. SET regulates hnRNPK. SET and hnRNPK accumulation promotes tumorigenesis. SET accumulation is a potential model to study genes regulated by SET-hnRNPK. - Abstract: SET and hnRNPK are proteins involved in gene expression and regulation of cellular signaling. We previously demonstrated that SET accumulates in head and neck squamous cell carcinoma (HNSCC); hnRNPK is a prognostic marker in cancer. Here, we postulate that SET and hnRNPK proteins interact to promote tumorigenesis. We performed studies in HEK293 and HNSCC (HN6, HN12, and HN13) cell lines with SET/hnRNPK overexpression and knockdown, respectively. We found that SET and/or hnRNPK protein accumulation increased cellular proliferation. SET accumulation up-regulated hnRNPK mRNA and total/phosphorylated protein, promoted hnRNPK nuclear location, and reduced Bcl-x mRNA levels. SET protein directly interacted with hnRNPK, increasing both its binding to nucleic acids and Bcl-xS repression. We propose that hnRNPK should be a new target of SET and that SEThnRNPK interaction, in turn, has potential implications in cell survival and malignant transformation.

  15. Dissolution of lead paint in aqueous solutions

    SciTech Connect (OSTI)

    Barnes, G.L.; Davis, A.P.

    1996-07-01

    An analysis of the rate and extent of lead leaching from a lead-based paint was completed. At low-solution pH, dissolution was rapid and approached 80% of the total lead. Residual lead can be estimated based on the predicted solubility of lead carbonate and basic lead carbonate. Release of lead from the paint was slower than that from pure basic lead carbonate due to inhibition by the paint matrix. Although the dissolved concentration of lead in solution at neutral/high pH was low, the paint binder was apparently destroyed at these pH values, releasing colloidal lead pigment particles. The presence of ethylenediaminetetraacetic acid (EDTA) and nitrilotriacetic acid (NTA) enhanced both the rate and degree of lead dissolution, while benzoic acid had a minimal effect.

  16. What is lead-based paint

    SciTech Connect (OSTI)

    Vernon, L.S.

    1994-03-01

    The number of variety of lead-abatement regulations and requirements make it difficult and confusing to identify and properly respond to dangerous levels of lead in every situation. Definitions of lead-based paint'' and three test methods for lead detection are described to help determine when and how to test for the presence of lead.

  17. Industrial lead paint removal specifications

    SciTech Connect (OSTI)

    Stone, R.C.

    1997-06-01

    The purpose of this paper is to inform the reader as to some of the pertinent rules and regulations promulgated by the Environmental Protection Agency (EPA) and the Occupational Safety and Health Administration (OSHA) that may effect an industrial lead paint removal project. The paper discusses a recommended schedule of procedures and preparations to be followed by the lead paint removal specification writer when analyzing the possible impact of the project on the environment, the public and workers. Implications of the Clean Air Act, the Clean Water Act and the Resource Conservation and Recovery Act (RCRA) along with hazardous waste handling, manifesting, transporting and disposal procedures are discussed with special emphasis placed as to their impact on the writer and the facility owner. As the rules and regulations are highly complex, the writer has attempted to explain the methodology currently being used in state-of-the-art industrial lead abatement specifications.

  18. Soluble Lead Flow Battery: Soluble Lead Flow Battery Technology

    SciTech Connect (OSTI)

    2010-09-01

    GRIDS Project: General Atomics is developing a flow battery technology based on chemistry similar to that used in the traditional lead-acid battery found in nearly every car on the road today. Flow batteries store energy in chemicals that are held in tanks outside the battery. When the energy is needed, the chemicals are pumped through the battery. Using the same basic chemistry as a traditional battery but storing its energy outside of the cell allows for the use of very low cost materials. The goal is to develop a system that is far more durable than todays lead-acid batteries, can be scaled to deliver megawatts of power, and which lowers the cost of energy storage below $100 per kilowatt hour.

  19. Acid mine drainage: Balancing environmental protection and mining realities

    SciTech Connect (OSTI)

    Sturgill, B.J. Jr.; Poland, K.B.

    1995-12-31

    A major environmental concern leading to the enactment of the Surface Mining Control and Reclamation Act of 1977 (SMCRA) was the degradation of streams and waterways from discharges of acid mine drainage (AMD) resulting from coal mining operations. Although SMCRA and its regulatory scheme contains specific provisions addressing the drainage of acidic water from mine sites, as do various other agencies statutes and regulations, AMD from active and abandoned mines remains a major environmental problem in the Appalachian region. The formation of acidic water during coal mining operations is pervasive and some believe impossible to prevent.

  20. Getting the Lead Out

    DOE R&D Accomplishments [OSTI]

    Gibson, Kerry

    2011-04-08

    Discarded electronics no longer pose an environmental hazard from lead solder thanks to a lead-free alternative developed at the Ames Laboratory.

  1. Functional nucleic acid probes and uses thereof

    DOE Patents [OSTI]

    Nilsen-Hamilton, Marit

    2006-10-03

    The present invention provides functional nucleic acid probes, and methods of using functional nucleic acid probes, for binding a target to carry out a desired function. The probes have at least one functional nucleic acid, at least one regulating nucleic acid, and at least one attenuator. The functional nucleic acid is maintained in an inactive state by the attenuator and activated by the regulating nucleic acid only in the presence of a regulating nucleic acid target. In its activated state the functional nucleic acid can bind to its target to carry out a desired function, such as generating a signal, cleaving a nucleic acid, or catalyzing a reaction.

  2. RNA-guided transcriptional regulation

    DOE Patents [OSTI]

    Church, George M.; Mali, Prashant G.; Esvelt, Kevin M.

    2016-02-23

    Methods of modulating expression of a target nucleic acid in a cell are provided including introducing into the cell a first foreign nucleic acid encoding one or more RNAs complementary to DNA, wherein the DNA includes the target nucleic acid, introducing into the cell a second foreign nucleic acid encoding a nuclease-null Cas9 protein that binds to the DNA and is guided by the one or more RNAs, introducing into the cell a third foreign nucleic acid encoding a transcriptional regulator protein or domain, wherein the one or more RNAs, the nuclease-null Cas9 protein, and the transcriptional regulator protein or domain are expressed, wherein the one or more RNAs, the nuclease-null Cas9 protein and the transcriptional regulator protein or domain co-localize to the DNA and wherein the transcriptional regulator protein or domain regulates expression of the target nucleic acid.

  3. VOLUMETRIC LEAD ASSAY

    SciTech Connect (OSTI)

    M.A. Ebadian, Ph.D.; S.K. Dua; David Roelant; Sachin Kumar

    2001-01-01

    This report describes a system for handling and radioassay of lead, consisting of a robot, a conveyor, and a gamma spectrometer. The report also presents a cost-benefit analysis of options: radioassay and recycling lead vs. disposal as waste.

  4. Down-regulation of p-coumaroyl quinate/shikimate 3'-hydroxylase (C3'H) and cinnamate 4-hydroxylase (C4H) genes in the lignin biosynthetic pathway of Eucalyptus urophylla x E. grandis leads to improved sugar release

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Sykes, Robert W.; Gjersing, Erica L.; Foutz, Kirk; Rottmann, William H.; Kuhn, Sean A.; Foster, Cliff E.; Ziebell, Angela; Turner, Geoffrey B.; Decker, Stephen R.; Hinchee, Maud A. W.; et al

    2015-08-27

    In this study, lignocellulosic materials provide an attractive replacement for food-based crops used to produce ethanol. Understanding the interactions within the cell wall is vital to overcome the highly recalcitrant nature of biomass. One factor imparting plant cell wall recalcitrance is lignin, which can be manipulated by making changes in the lignin biosynthetic pathway. In this study, eucalyptus down-regulated in expression of cinnamate 4-hydroxylase (C4H, EC 1.14.13.11) or p-coumaroyl quinate/shikimate 3'-hydroxylase (C3'H, EC 1.14.13.36) were evaluated for cell wall composition and reduced recalcitrance.

  5. Lead carbonate scintillator materials

    DOE Patents [OSTI]

    Derenzo, Stephen E. (Pinole, CA); Moses, William W. (Berkeley, CA)

    1991-01-01

    Improved radiation detectors containing lead carbonate or basic lead carbonate as the scintillator element are disclosed. Both of these scintillators have been found to provide a balance of good stopping power, high light yield and short decay constant that is superior to other known scintillator materials. The radiation detectors disclosed are favorably suited for use in general purpose detection and in medical uses.

  6. Managing lead-based paint abatement wastes

    SciTech Connect (OSTI)

    Steele, N.L.C.

    1994-12-31

    Renovation, remodeling, demolition, and surface preparation for painting, in addition to specified lead abatement, are all activities that have the potential to produce hazardous wastes if a property was painted with lead-based paint. Lead-based paint was used on residential structures until 1978, when most residential uses were banned by the Consumer Products Safety Council. Prior to the 1950s, paints for residential uses may have contained up to 50% lead by weight. Today, commercial and military paints may still contain lead and can be used on non-residential structures. The lead content of residential paints is limited to 0.06% lead (by weight) in the dried film. This paper provides an overview of some of the information needed to properly manage lead-based paint abatement wastes. The issues covered in this paper include waste classification, generator status, treatment, and land disposal restrictions. The author assumes that the reader is familiar with the provision of the Health and Safety Code and the California Code of Regulations that pertain to generation and management of hazardous wastes. Citations provided herein do not constitute an exhaustive list of all the regulations with which a generator of hazardous waste must comply.

  7. lead paint chart

    Office of Environmental Management (EM)

    1930 Assume Lead Will WX Disturb Paint? No Yes Will WX Disturb More than 2 ft 2 . per Room? Yes HUD Housing or Using HUD ? Yes More than 50ugm 3 ? No LSW & HUD Rule 35.900 **...

  8. Lead carbonate scintillator materials

    DOE Patents [OSTI]

    Derenzo, S.E.; Moses, W.W.

    1991-05-14

    Improved radiation detectors containing lead carbonate or basic lead carbonate as the scintillator element are disclosed. Both of these scintillators have been found to provide a balance of good stopping power, high light yield and short decay constant that is superior to other known scintillator materials. The radiation detectors disclosed are favorably suited for use in general purpose detection and in medical uses. 3 figures.

  9. Evaluation of lead/carbon devices for utility applications : a study for the DOE Energy Storage Program.

    SciTech Connect (OSTI)

    Walmet, Paula S.

    2009-06-01

    This report describes the results of a three-phase project that evaluated lead-based energy storage technologies for utility-scale applications and developed carbon materials to improve the performance of lead-based energy storage technologies. In Phase I, lead/carbon asymmetric capacitors were compared to other technologies that used the same or similar materials. At the end of Phase I (in 2005) it was found that lead/carbon asymmetric capacitors were not yet fully developed and optimized (cost/performance) to be a viable option for utility-scale applications. It was, however, determined that adding carbon to the negative electrode of a standard lead-acid battery showed promise for performance improvements that could be beneficial for use in utility-scale applications. In Phase II various carbon types were developed and evaluated in lead-acid batteries. Overall it was found that mesoporous activated carbon at low loadings and graphite at high loadings gave the best cycle performance in shallow PSoC cycling. Phase III studied cost/performance benefits for a specific utility application (frequency regulation) and the full details of this analysis are included as an appendix to this report.

  10. Generating Energy Efficiency Project Leads and Allocating Leads to Contractors

    Broader source: Energy.gov [DOE]

    Better Buildings Residential Network Peer Exchange Call Series: Generating Energy Efficiency Project Leads and Allocating Leads to Contractors, Call Slides and Discussion Summary February 26, 2015.

  11. WPN 08-6: Interim Lead-Safe Weatherization Guidance

    Broader source: Energy.gov [DOE]

    To provide additional guidance for an LSW component of a health and safety plan. This guidance builds on the foundation provided in WPN 02-6, Weatherization Activities and Federal Lead Based Paint Regulations.

  12. Home refinishing, lead paint, and infant blood lead levels

    SciTech Connect (OSTI)

    Rabinowitz, M.; Leviton, A.; Bellinger, D.

    1985-04-01

    The blood lead levels of 249 infants were measured semi-annually from birth to two years of age; the home paint was sampled and any recent home refinishing activity recorded. Mean blood lead from birth to age 2 years did not vary systematically with age but did correlate significantly with the amount of lead in the indoor paint. Refinishing activity in homes with high lead paint was associated with elevations of blood lead averaging 69 per cent.

  13. Breakthrough: Lead-free Solder

    ScienceCinema (OSTI)

    Anderson, Iver

    2013-03-01

    Ames Laboratory senior metallurgist Iver Anderson explains the importance of lead-free solder in taking hazardous lead out of the environment by eliminating it from discarded computers and electronics that wind up in landfills. Anderson led a team that developed a tin-silver-copper replacement for traditional lead-tin solder that has been adopted by more than 50 companies worldwide.

  14. Lead-based paint assessment

    SciTech Connect (OSTI)

    Lorie, C.; Cowdery, J.W.

    1994-12-31

    In 1977, The US consumer product safety commission banned the use of lead-based paint (LBP) in all industries, except the maritime industry which still has certain privileged uses. Unfortunately for property and building owners, the ban did not come soon enough. In response to this heightened awareness, several environmental market sectors addressing the issues have emerged. These include: residential; soil; commercial; water; and structures. The first and most important step in addressing the concerns posed by the existence of lead based contamination is to quantify the amount of lead-based product, to determine the location of the lead based product and the extent, if any, of lead based contamination, and to make recommendations for the remediation or abatement of the lead product and resultant contamination. In narrowing the focus of these issues, this paper discusses lead-based paint assessment; preparing and organizing the assessment, the regulatory considerations, assessment methodology, and presentation of results.

  15. High temperature superconductor current leads

    DOE Patents [OSTI]

    Hull, John R. (Hinsdale, IL); Poeppel, Roger B. (Glen Ellyn, IL)

    1995-01-01

    An electrical lead having one end for connection to an apparatus in a cryogenic environment and the other end for connection to an apparatus outside the cryogenic environment. The electrical lead includes a high temperature superconductor wire and an electrically conductive material distributed therein, where the conductive material is present at the one end of the lead at a concentration in the range of from 0 to about 3% by volume, and at the other end of the lead at a concentration of less than about 20% by volume. Various embodiments are shown for groups of high temperature superconductor wires and sheaths.

  16. High temperature superconductor current leads

    DOE Patents [OSTI]

    Hull, J.R.; Poeppel, R.B.

    1995-06-20

    An electrical lead is disclosed having one end for connection to an apparatus in a cryogenic environment and the other end for connection to an apparatus outside the cryogenic environment. The electrical lead includes a high temperature superconductor wire and an electrically conductive material distributed therein, where the conductive material is present at the one end of the lead at a concentration in the range of from 0 to about 3% by volume, and at the other end of the lead at a concentration of less than about 20% by volume. Various embodiments are shown for groups of high temperature superconductor wires and sheaths. 9 figs.

  17. One Vaccine Leads to Another

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    One Vaccine Leads to Another Print Diphtheria is a potentially lethal respiratory disease that is fairly well controlled by vaccines discovered early last century. These vaccines...

  18. Lead-free primary explosives

    DOE Patents [OSTI]

    Huynh, My Hang V.

    2010-06-22

    Lead-free primary explosives of the formula (cat).sub.Y[M.sup.II(T).sub.X(H.sub.2O).sub.6-X].sub.Z, where T is 5-nitrotetrazolate, and syntheses thereof are described. Substantially stoichiometric equivalents of the reactants lead to high yields of pure compositions thereby avoiding dangerous purification steps.

  19. Regulations | Department of Energy

    Energy Savers [EERE]

    Information Center » Regulations Regulations Personnel Security Regulations Click Here FOIA Regulations Click Here Privacy Act Regulations Click Here Whistleblower Protection Regulations Click Here Exception Regulations Click Here Procedural Regulations Click Here Browse Title 10 Energy Regulations Click Here Annual Reports Filing Information FOIA Decisions Security Hearings Decisions Whistleblower Decisions EIA Decisions Oil Refund Decisions Product Efficiency Decisions Decision Summaries

  20. One Vaccine Leads to Another

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    One Vaccine Leads to Another One Vaccine Leads to Another Print Friday, 24 May 2013 11:19 Diphtheria is a potentially lethal respiratory disease that is fairly well controlled by vaccines discovered early last century. These vaccines have been extremely effective; studies on one vaccine in particular, the nontoxic form of the diphtheria toxin (DT), have informed other vaccines. Recently, researchers at Novartis GNF solved several structures of a nontoxic DT using data obtained at ALS Beamline

  1. WPN 02-6: Weatherization Activities and Federal Lead-Based Paint

    Broader source: Energy.gov (indexed) [DOE]

    Regulations | Department of Energy July 12, 2002 Replaces WPN 01-10 issued May 10, 2001, and provides updated guidance to regional offices and states relative to weatherization health and safety matters associated with lead-based paint in homes. PDF icon WPN 02-6: Weatherization Activities and Federal Lead-Based Paint Regulations PDF icon Other Federal Government Regulations Pertaining to Lead-Based Paint PDF icon Low-Income Home Energy Assistance PDF icon Lead Paint Decision Chart More

  2. Acquisition Regulation

    Energy Savers [EERE]

    6 Rev. 1 Date 09/09/2015 Department of Energy No. FAL 2015-04 Rev. 1 Date 09/09/2015 Financial Assistance Regulations ACQUISITION/FINANCIAL ASSISTANCE LETTER This Acquisition/Financial Assistance Letter is issued under the authority of the Senior Procurement Executive of DOE. It is intended for use by procurement professionals of DOE, primarily Contracting Officers, and other officials of DOE that are involved in the acquisition process. Other parties are welcome to its information, but

  3. Crystal structure of Spot 14, a modulator of fatty acid synthesis

    SciTech Connect (OSTI)

    Colbert, Christopher L.; Kim, Chai-Wan; Moon, Young-Ah; Henry, Lisa; Palnitkar, Maya; McKean, William B.; Fitzgerald, Kevin; Deisenhofer, Johann; Horton, Jay D.; Kwon, Hyock Joo

    2011-09-06

    Spot 14 (S14) is a protein that is abundantly expressed in lipogenic tissues and is regulated in a manner similar to other enzymes involved in fatty acid synthesis. Deletion of S14 in mice decreased lipid synthesis in lactating mammary tissue, but the mechanism of S14's action is unknown. Here we present the crystal structure of S14 to 2.65 {angstrom} and biochemical data showing that S14 can form heterodimers with MIG12. MIG12 modulates fatty acid synthesis by inducing the polymerization and activity of acetyl-CoA carboxylase, the first committed enzymatic reaction in the fatty acid synthesis pathway. Coexpression of S14 and MIG12 leads to heterodimers and reduced acetyl-CoA carboxylase polymerization and activity. The structure of S14 suggests a mechanism whereby heterodimer formation with MIG12 attenuates the ability of MIG12 to activate ACC.

  4. Leading the Charge: Christine Klein

    Broader source: Energy.gov [DOE]

    Change doesn’t happen on its own. It’s led by dedicated and passionate people who are committed to empowering Indian Country to energize future generations. Leading the Charge is a regular Office of Indian Energy newsletter feature spotlighting the movers and shakers in energy development on tribal lands. In this issue, we talk to Christine Klein, an adopted Haida who is leading efforts to help Alaska Native villages address their energy challenges in her role as Vice President and Chief Operating Officer of the Calista Corporation.

  5. Batteries called primary source of lead, cadmium in municipal waste

    SciTech Connect (OSTI)

    Not Available

    1989-04-01

    The US Environmental Protection Agency reports that lead-acid batteries, such as those used in automobiles, and rechargeable nickel-cadmium batteries used in consumer electronics equipment, are the primary sources of lead and cadmium in municipal trash and garbage. A report prepared for EPA analyzed existing data from 1970 to 1986 and made projections to the year 2000. Lead-acid batteries continue to constitute a major source of lead in garbage even though 80 percent of them are now recycled. As a result, EPA is calling for additional recycling of batteries. This study is an important step in implementing EPA's strategy for helping states and cities achieve the national goal of recycling and reducing 25 percent of all municipal garbage by 1992. The findings on batteries are the result of a study conducted for EPA because of concern over the levels of lead and cadmium found n ash (residue) from municipal waste incinerators. Lead and cadmium are two metals of particular concern in the solid waste stream. The metals can contaminate soil and groundwater when landfilled. They also may be found in some incinerator emissions.

  6. NATIONAL LEAD COMPANY OF OHIO

    Office of Legacy Management (LM)

    t-t AL- 1. + T fi r,y* t ,.- . NATIONAL LEAD COMPANY OF OHIO Ofll i iy Ci)wp HEALTH AND SAFETY DIVISION - ANALYTICAL DEPT. ANALYTICAL DATA SHEET U-G b ;33y jl:tL G c-w &3(y I...

  7. Regulations | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Regulations Regulations Security Reviews Click Here FOIA Appeals Click Here Whistleblower Protection Click Here Procedural Regulations Click Here Browse Title 10 Energy Click Here

  8. Charge regulation circuit

    DOE Patents [OSTI]

    Ball, Don G. (Livermore, CA)

    1992-01-01

    A charge regulation circuit provides regulation of an unregulated voltage supply in the range of 0.01%. The charge regulation circuit is utilized in a preferred embodiment in providing regulated voltage for controlling the operation of a laser.

  9. Hydroxycarboxylic acids and salts

    DOE Patents [OSTI]

    Kiely, Donald E; Hash, Kirk R; Kramer-Presta, Kylie; Smith, Tyler N

    2015-02-24

    Compositions which inhibit corrosion and alter the physical properties of concrete (admixtures) are prepared from salt mixtures of hydroxycarboxylic acids, carboxylic acids, and nitric acid. The salt mixtures are prepared by neutralizing acid product mixtures from the oxidation of polyols using nitric acid and oxygen as the oxidizing agents. Nitric acid is removed from the hydroxycarboxylic acids by evaporation and diffusion dialysis.

  10. NATIONAL LEAD ,COMPANY OF OHIO

    Office of Legacy Management (LM)

    tic.. 02-j . . NATIONAL LEAD ,COMPANY OF OHIO 2186002 I ,""ll"IAWl OF NL. I~rl>"Or"ICI. INC. CINCINNATI. OHIO 45239 June 1, 1979 TRIP REPORT - VISIT M THORILIM STORAGE FACILITY OF GEN?BAL ATOMIC, SUBJECT YOUNGSVILLE. NORTII CAROLINA - ,NAAy 21 and 22, 1979 ~TO / W. W. W right and R. C. llcathcrton FROM REFERENCE Letter, H. D; Hickman to S. F. Audia dated May 11, 1979, Subject: General Atomic Thorium Stockpiie i sonatiOn.tO WE OBJECTIVE OF TRIP: The purpose'of the

  11. NATIONAL LEAD COMPANY OF OHIO

    Office of Legacy Management (LM)

    .' HEALTH AND SAFETY DIVJSION - ANALYTICAL DEPT. I ' .' _. ANALY' TICAL DATA SHEET NUI ' I NO. DISTRIBUTION OF COPIES 1 Analytical Laboratory (RBCCRD COPPI 2 Industrial Hygiene 8 Radiatlon Dept. 3 Water Treatment Plant (Far W&or Spnphs Only) NILHhS-1?6 (RFV lO/lU/ficlr NATIONAL LEAD COMPANY OF OHIO HEALTH AND SAFETY DIVKJON - ANALYTICAL DEPT. ANALYTICAL DATA SHEET Gleixor. work SAMPLE HOUR SAMPLE R T Q NO. DESCR I PTI ON Xeservoir floor of c,uerc!~ .1-,ach. I I I ' NO. DISTRIBUTION OF COPIES

  12. NATIONAL LEAD COMPANY OF OHIO

    Office of Legacy Management (LM)

    -- $+I + 1 c NATIONAL LEAD COMPANY OF OHIO r. 0. WI lB6. MT. HcALmw CIITION CINCINNATI 31. OHIO April 23, 1956 SUBJECT TRIP REPORT TO KNOXVILLE IRON COMPANY, KNOXVILLE, TENNESSZE, ON APRIL 20, 1956 TO J. A. QuigleY, M.D. FROM R. C, Heatherton REFERENCE OBJECTIVE OF TRIP: CEtiTilAL FILES The purpose of this trip was to look over facilities for melting steel scrap and to obtain information concerning available facilities in order to plan an Industrial Hygiene survey in conjunction with a test melt

  13. NATIONAL LEAD COMPANY OF OHIO

    Office of Legacy Management (LM)

    ~y-f-hjLo-- yy; 4: j ).,Ic +- NATIONAL LEAD COMPANY OF OHIO s _ HEALTH AND SAFETY DIVISION - ANALYTICAL DEPT. . ANALYTICAL DATA SHEET o-0 1. H. NO. TRIAL, HYGIENE AND RADIATION DEPT. AMPLE Nti.1. //- 6:itEC TEDI it/;/L 5 .,- -..-- -- -.._-. -. I --- --- 1 ANALYTICA .OATE RECeiVEDi mri /-2-v& 3 Li >,a. HCJ _-..k.-*..- -.v._ 1 NO. DISTRIBUTION OF COPIES 1 Analytlcal Labwatwy (RECORD COPP) 2 Industrial Hygiene 8 Radlation Dept. . 3' Water Treatment Plant (Far Water Smmplos Only)' t' , /,' 30

  14. Multi-lead heat sink

    DOE Patents [OSTI]

    Roose, Lars D. (Albuquerque, NM)

    1984-01-01

    The disclosure relates to a heat sink used to protect integrated circuits from the heat resulting from soldering them to circuit boards. A tubular housing contains a slidable member which engages somewhat inwardly extending connecting rods, each of which is rotatably attached at one end to the bottom of the housing. The other end of each rod is fastened to an expandable coil spring loop. As the member is pushed downward in the housing, its bottom edge engages and forces outward the connecting rods, thereby expanding the spring so that it will fit over an integrated circuit. After the device is in place, the member is slid upward and the spring contracts about the leads of the integrated circuit. Soldering is now conducted and the spring absorbs excess heat therefrom to protect the integrated circuit. The placement steps are repeated in reverse order to remove the heat sink for use again.

  15. Multi-lead heat sink

    DOE Patents [OSTI]

    Roose, L.D.

    1982-08-25

    The disclosure relates to a heat sink used to protect integrated circuits from the heat resulting from soldering them to circuit boards. A tubular housing contains a slidable member which engages somewhat inwardly extending connecting rods, each of which is rotatably attached at one end to the bottom of the housing. The other end of each rod is fastened to an expandable coil spring loop. As the member is pushed downward in the housing, its bottom edge engages and forces outward the connecting rods, thereby expanding the spring so that it will fit over an integrated circuit. After the device is in place, the member is slid upward and the spring contracts about the leads of the integrated circuit. Soldering is now conducted and the spring absorbs excess heat therefrom to protect the integrated circuit. The placement steps are repeated in reverse order to remove the heat sink for use again.

  16. Multi-lead heat sink

    DOE Patents [OSTI]

    Roose, L.D.

    1984-07-03

    The disclosure relates to a heat sink used to protect integrated circuits from the heat resulting from soldering them to circuit boards. A tubular housing contains a slidable member which engages somewhat inwardly extending connecting rods, each of which is rotatably attached at one end to the bottom of the housing. The other end of each rod is fastened to an expandable coil spring loop. As the member is pushed downward in the housing, its bottom edge engages and forces outward the connecting rods, thereby expanding the spring so that it will fit over an integrated circuit. After the device is in place, the member is slid upward and the spring contracts about the leads of the integrated circuit. Soldering is now conducted and the spring absorbs excess heat therefrom to protect the integrated circuit. The placement steps are repeated in reverse order to remove the heat sink for use again. 4 figs.

  17. NATIONAL LEAD COMPANY OF OHIO

    Office of Legacy Management (LM)

    t-t AL- 1. + T fi r,y* t ,.- . NATIONAL LEAD COMPANY OF OHIO Of~~l=l i iy Ci)wp HEALTH AND SAFETY DIVISION - ANALYTICAL DEPT. ANALYTICAL DATA SHEET U-G b ;33y jl:tL G c-w &3(/y I 53 .3 Y5 .y j.os-- ! stz77y t3r1: my I CLvru' f<? 3;/ ' > j!OS ! I I I 1 P-/) ' If I , m 6.3 Lg- /&IL -q-&.+&L, /I a V Q/);: /(Lx 3L- NO. DISTRIBUTION OF COPIES 1 Analytical Laboratory (RECORD COPY) 2 Industrial Hygiene 8 Radiation Dept. Plnnt NLO-HbS-736 IREV. lo/:m4/601 - -_.-__- - ---

  18. David Skinner Named NERSC Strategic Partnerships Lead

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    David Skinner Named NERSC Strategic Partnerships Lead David Skinner Named NERSC Strategic Partnerships Lead January 24, 2014 Contact: Linda Vu, +1 510 495 2402, lvu@lbl.gov...

  19. Lead phosphate glass compositions for optical components

    DOE Patents [OSTI]

    Sales, Brian C. (Oak Ridge, TN); Boatner, Lynn A. (Oak Ridge, TN)

    1987-01-01

    A lead phosphate glass to which has been added indium oxide or scandium oe to improve chemical durability and provide a lead phosphate glass with good optical properties.

  20. Low Emissions Asian Development (LEAD) Program - Bangladesh ...

    Open Energy Info (EERE)

    Low Emissions Asian Development (LEAD) Program - Bangladesh Redirect page Jump to: navigation, search REDIRECT Low Emissions Asian Development (LEAD) Program Retrieved from...

  1. Cities Leading through Energy Analysis and Planning

    Broader source: Energy.gov [DOE]

    The Cities Leading through Energy Analysis and Planning (Cities-LEAP) project delivers standardized, localized energy data and analysis that enables cities to lead clean energy innovation and...

  2. SU-E-P-09: Radiation Transmission Measurements and Evaluation of Diagnostic Lead-Based and Lead-Free Aprons

    SciTech Connect (OSTI)

    Syh, J

    2014-06-01

    Purpose: This study was conducted to ensure that various lead shield apron manufacturers provided accurate attenuation factors regardless of whether the apron was made of lead-based or lead-free equivalent material. Methods: A calibrated ionization survey meter was placed at chest height and 36 cm horizontally away from a solid water phantom on a simulator couch. Measurements were done with or without apron. Radiation field was set to 24cmx24cm with the phantom at 100cm source-to-surface distance. Irradiation time was set for 1 minute at voltages of 60, 80, 100 and 120 kVp. Current was set at 6mA. Results: Between 60 kVp and 120 kVp, the transmission through 0.50 mm of lead-based apron was between 1.0% and 6.5% with a mean value of 3.2% and a standard deviation (s.d.) of 1.4%. The transmissions through the 0.50 mm lead-free aprons were 1.0 % to 12.0% with a mean value of 6.1% and s.d. of 2.6%. At 120 kVp, the transmission value was 6.5% for 0.50 mm lead-based apron and 11.1% to 12.0% for 0.50 mm lead-free aprons. The radiation transmissions at 80 kVp, measured in two different 0.5 mm lead-free aprons, were 4.3% each. However, only 1.4% transmission was found through the lead-based apron. Overall, the radiation transmitted through the lead-based apron was 1/3 transmission of lead-free at 80kVp, and half value of lead-free aprons at 100 and 120 kVp. Conclusion: Even though lead-based and lead-free aprons all claimed to have the same lead equivalent thickness, the transmission might not be the same. The precaution was needed to exercise diligence in quality assurance program to assure adequate protection to staff who wear it during diagnostic procedures. The requirement for aprons not only should be in certain thickness to meet state regulation but also to keep reasonably achievable low exposure with the accurate labeling from manufacturers.

  3. Regulators, Requirements, Statutes

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Regulators, Requirements, Statutes Regulators, Requirements, Statutes The Laboratory must comply with environmental laws and regulations that apply to Laboratory operations. Contact Environmental Communication & Public Involvement P.O. Box 1663 MS M996 Los Alamos, NM 87545 (505) 667-0216 Email Environmental laws and regulations LANL complies with more than 30 state and federal regulations and policies designed to protect human health and the environment. Regulators Regulators Environmental

  4. Isotopic generator for bismuth-212 and lead-212 from radium

    DOE Patents [OSTI]

    Atcher, Robert W. (Kensington, MD); Friedman, Arnold M. (Park Forest, IL); Hines, John (Glen Ellyn, IL)

    1987-01-01

    A method and apparatus for providing radionuclides of bismuth-212 and lead-212. Thorium-228 and carrier solution starting material is input to a radiologically contained portion of an isotopic generator system, and radium-224 is separated from thorium-228 which is retained by a strongly basic anion exchange column. The separated radium-224 is transferred to an accessible, strongly acidic cationic exchange column. The cationic column retains the radium-224, and natural radioactive decay generates bismuth-212 and lead-212. The cationic exchange column can also be separated from the contained portion of the system and utilized without the extraordinary safety measures necessary in the contained portion. Furthermore, the cationic exchange column provides over a relatively long time period the short lived lead-212 and bismuth-212 radionuclides which are useful for a variety of medical therapies.

  5. C-Myc Induced Compensated Cardiac Hypertrophy Increases Free Fatty Acid Utilization for the Citric Acid Cycle

    SciTech Connect (OSTI)

    Olson, Aaron; Ledee, Dolena; Iwamoto, Kate; Kajimoto, Masaki; O'Kelly-Priddy, Colleen M.; Isern, Nancy G.; Portman, Michael A.

    2013-02-01

    The protooncogene C-Myc (Myc) regulates cardiac hypertrophy. Myc promotes compensated cardiac function, suggesting that the operative mechanisms differ from those leading to heart failure. Myc regulation of substrate metabolism is a reasonable target, as Myc alters metabolism in other tissues. We hypothesize that Myc-induced shifts in substrate utilization signal and promote compensated hypertrophy. We used cardiac specific Myc-inducible C57/BL6 male mice between 4-6 months old that develop hypertrophy with tamoxifen (tam). Isolated working hearts and 13Carbon (13C )-NMR were used to measure function and fractional contributions (Fc) to the citric acid cycle by using perfusate containing 13C-labeled free fatty acids, acetoacetate, lactate, unlabeled glucose and insulin. Studies were performed at pre-hypertrophy (3-days tam, 3dMyc), established hypertrophy (7-days tam, 7dMyc) or vehicle control (cont). Non-transgenic siblings (NTG) received 7-days tam or vehicle to assess drug effect. Hypertrophy was confirmed by echocardiograms and heart weights. Western blots were performed on key metabolic enzymes. Hypertrophy occurred in 7dMyc only. Cardiac function did not differ between groups. Tam alone did not affect substrate contribution in NTG. Substrate utilization was not significantly altered in 3dMyc versus cont. The free fatty acid FC was significantly greater in 7dMyc vs cont with decreased unlabeled Fc, which is predominately exogenous glucose. Free fatty acid flux to the citric acid cycle increased while lactate flux was diminished in 7dMyc compared to cont. Total protein levels of a panel of key metabolic enzymes were unchanged; however total protein O-GlcNAcylation was increased in 7dMyc. Substrate utilization changes did not precede hypertrophy; therefore they are not the primary signal for cardiac growth in this model. Free fatty acid utilization and oxidation increase at established hypertrophy. Understanding the mechanisms whereby this change maintained compensated function could provide useful information for developing metabolic therapies to treat heart failure. The molecular signaling for this metabolic change may occur through O-GlcNAcylation.

  6. Results from the Cooler and Lead Tests

    SciTech Connect (OSTI)

    Green, Michael A

    2010-06-10

    The report presents the results of testing MICE spectrometer magnet current leads on a test apparatus that combines both the copper leads and the high temperature superconducting (HTS) leads with a single Cryomech PT415 cooler and liquid helium tank. The current is carried through the copper leads from 300 K to the top of the HTS leads. The current is then carried through the HTS leads to a feed-through from the vacuum space to the inside of a liquid helium tank. The experiment allows one to measure the performance of both cooler stages along with the performance of the leads. While the leads were powered we measured the voltage drops through the copper leads, through the HTS leads, through spliced to the feed-through, through the feed-through and through the low-temperature superconducting loop that connects one lead to the other. Measurements were made using the leads that were used in spectrometer magnet 1A and spectrometer magnet 2A. These are the same leads that were used for Superbend and Venus magnets at LBNL. The IL/A for these leads was 5.2 x 10{sup 6} m{sup -1}. The leads turned out to be too long. The same measurements were made using the leads that were installed in magnet 2B. The magnet 2B leads had an IL/A of 3.3 x 10{sup 6} A m{sup -1}. This report discusses the cooler performance and the measured electrical performance of the lead circuit that contains the copper leads and the superconducting leads. All of the HTS leads that were installed in magnet 2B were current tested using this apparatus.

  7. Thermal Stability of Acetohydroxamic Acid/Nitric Acid Solutions

    SciTech Connect (OSTI)

    Rudisill, T.S.

    2002-03-13

    The transmutation of transuranic actinides and long-lived fission products in spent commercial nuclear reactor fuel has been proposed as one element of the Advanced Accelerator Applications Program. Preparation of targets for irradiation in an accelerator-driven subcritical reactor would involve dissolution of the fuel and separation of uranium, technetium, and iodine from the transuranic actinides and other fission products. The UREX solvent extraction process is being developed to reject and isolate the transuranic actinides in the acid waste stream by scrubbing with acetohydroxamic acid (AHA). To ensure that a runaway reaction will not occur between nitric acid and AHA, an analogue of hydroxyl amine, thermal stability tests were performed to identify if any processing conditions could lead to a runaway reaction.

  8. WPN 09-6: Lead Safe Weatherization (LSW) Additional Materials and Information

    Broader source: Energy.gov [DOE]

    To provide clarification and additional information to grantees as they implement WPN 08-6, Interim Lead-Safe Weatherization Guidance. This guidance augments, but does not replace, WPN 08-6 and builds on the foundation provided in WPN 02-6, Weatherization Activities and Federal Lead Based Paint Regulations.

  9. Review of current research and activities involving characterization, abatement, and disposal of lead-containing paint films

    SciTech Connect (OSTI)

    McKnight, M.E.

    1990-05-01

    In response to a recent regulation for abating lead-based paint in housing and other environmental regulations, research projects and other activities are being conducted to provide information on procedures for carrying out abatement and maintenance of lead-containing paint films in a safe and cost-effective manner. Relevant Federal regulations, and current research projects and other activities addressing the issues are reviewed.

  10. Kolorsafe Liquid Acid Neutralizer Safety Data Sheet

    Office of Environmental Management (EM)

    Kolorsafe Liquid Acid Neutralizer Safety Data Sheet according to Federal Register / Vol. 77, No. 58 / Monday, March 26, 2012 / Rules and Regulations Revision Date: 03/07/2014 Date of issue: 03/07/2014 Version: 1.0 03/07/2014 EN (English US) 1/8 SECTION 1: IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY Product Identifier Product Form: Mixture Product Name: Kolorsafe Liquid Acid Neutralizer Product Code: 4100 series Intended Use of the Product Spill cleanup/ neutralize acids. For

  11. Prabhat Steps In as DAS Group Lead

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Prabhat Steps In as DAS Group Lead Prabhat Steps In as DAS Group Lead September 1, 2014 prabhat Prabhat has been named Group Lead of the Data and Analytics Services (DAS) Group at the Department of Energy's National Energy Research Scientific Computing Center (NERSC). The DAS group helps NERSC's users address data and analytics challenges arising from the increasing size and complexity of data from simulations and experiments. As the DAS Group Lead, Prabhat will play a key role in developing and

  12. Clean Lead Facility (CLF) Inventory System

    Energy Science and Technology Software Center (OSTI)

    1995-07-13

    The CLF Inventory System records shipments of clean or nonradioactive contaminated lead stored at the CLF. The Inventory System provides reports and inventory information to Facility operators. Annual, quarterly, monthly, and current inventory reports may be printed. Profile reports of each shipment of lead may also be printed for verification and documentation of lead transactions.

  13. Reproductive toxicity of low-level lead exposure in men

    SciTech Connect (OSTI)

    Telisman, Spomenka Colak, Bozo; Pizent, Alica; Jurasovic, Jasna; Cvitkovic, Petar

    2007-10-15

    Parameters of semen quality, seminal plasma indicators of secretory function of the prostate and seminal vesicles, sex hormones in serum, and biomarkers of lead, cadmium, copper, zinc, and selenium body burden were measured in 240 Croatian men 19-52 years of age. The subjects had no occupational exposure to metals and no known other reasons suspected of influencing male reproductive function or metal metabolism. After adjusting for age, smoking, alcohol, blood cadmium, and serum copper, zinc, and selenium by multiple regression, significant (P<0.05) associations of blood lead (BPb), {delta}-aminolevulinic acid dehydratase (ALAD), and/or erythrocyte protoporphyrin (EP) with reproductive parameters indicated a lead-related increase in immature sperm concentration, in percentages of pathologic sperm, wide sperm, round sperm, and short sperm, in serum levels of testosterone and estradiol, and a decrease in seminal plasma zinc and in serum prolactin. These reproductive effects were observed at low-level lead exposure (BPb median 49 {mu}g/L, range 11-149 {mu}g/L in the 240 subjects) common for general populations worldwide. The observed significant synergistic effect of BPb and blood cadmium on increasing serum testosterone, and additive effect of a decrease in serum selenium on increasing serum testosterone, may have implications on the initiation and development of prostate cancer because testosterone augments the progress of prostate cancer in its early stages.

  14. David Skinner Named NERSC Strategic Partnerships Lead

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    David Skinner Named NERSC Strategic Partnerships Lead David Skinner Named NERSC Strategic Partnerships Lead January 24, 2014 Contact: Linda Vu, +1 510 495 2402, lvu@lbl.gov XBD201102-00089.jpg David Skinner This month, the National Energy Research Scientific Computing Center (NERSC) created a new position-Strategic Partnerships Lead, to identify new science communities that can benefit from NERSC resources. David Skinner, former head of NERSC's Outreach Software and Programming Group (OSP), has

  15. Property:LeadAgency | Open Energy Information

    Open Energy Info (EERE)

    Subproperties This property has the following 1 subproperty: R RAPIDRoadmap9-FD-k Pages using the property "LeadAgency" Showing 25 pages using this property. (previous...

  16. Compatibility of PETN with lead azide

    SciTech Connect (OSTI)

    Hurd, R.; Fronabarger, J.W.; Johnson, R.; Fleming, W.

    1983-01-01

    The compatibility of PETN with lead azide at elevated temperatures has been investigated. Ramped and isothermal DSC methods were used to obtain energies of activation at temperatures above the melting point of PETN. Mixtures were found to show exothermic activity at lower temperatures than pure PETN. High Pressure Liquid Chromatography was used to follow the decomposition of PETN and PETN/lead azide mixtures at temperatures below the melting point. Reaction below 120/sup 0/C appeared minimal, while at higher temperatures, both PETN and PETN/lead azide mixtures showed degradation. A PETN/lead azide sample exploded at or near the melting point of PETN.

  17. Power Marketing Administrations Leading the Nation's Transition...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Leading the Nation's Transition to a 21st Century Electric Grid Power Marketing ... The Energy Department's Power Marketing Administrations (PMAs) play a vital role in ...

  18. LEAD SUBSTITUTION AND ELIMINATION STUDY, PART II

    SciTech Connect (OSTI)

    T. MARTINEZ; M. COURNOYER

    2001-01-01

    Within the Nuclear Materials Technology Division of Los Alamos National Laboratory, lead is used as shielding for a variety of operations, including actinide chemistry, weapons production, radiochemistry, and analytical chemistry. In this study, waste minimization issues associated with replacing lead shielding with non-hazardous materials are addressed. These include institutional program available to support this effort, the hazards and accompanying controls grouped with lead shielding, operations that use lead bricks and how this effects the selection of the substitute. Life cycle management issues are also examined. As a final step, an approach to get buy-in from both technical and budget minded employees is presented.

  19. Interviewee Travel Regulations Scope

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    23/2012 Interviewee Travel Regulations Scope These regulations apply to the reimbursement of round-trip travel expenses incurred by interviewees. These regulations do not apply to applicants who live within a 50-mile radius of Los Alamos based on the Rand McNally Standard Highway Mileage Guide. Reimbursement With the exception of airfare, interviewees will be reimbursed for travel expenses according to Federal travel regulations. For interviewees, airfare reimbursement is limited to the lesser

  20. Molecular recognition of nitrated fatty acids by PPAR[gamma

    SciTech Connect (OSTI)

    Li, Yong; Zhang, Jifeng; Schopfer, Francisco J.; Martynowski, Dariusz; Garcia-Barrio, Minerva T.; Kovach, Amanda; Suino-Powell, Kelly; Baker, Paul R.S.; Freeman, Bruce A.; Chen, Y. Eugene; Xu, H. Eric

    2010-03-08

    Peroxisome proliferator activated receptor-{gamma} (PPAR{gamma}) regulates metabolic homeostasis and adipocyte differentiation, and it is activated by oxidized and nitrated fatty acids. Here we report the crystal structure of the PPAR{gamma} ligand binding domain bound to nitrated linoleic acid, a potent endogenous ligand of PPAR{gamma}. Structural and functional studies of receptor-ligand interactions reveal the molecular basis of PPAR{gamma} discrimination of various naturally occurring fatty acid derivatives.

  1. Load regulating expansion fixture

    DOE Patents [OSTI]

    Wagner, Lawrence M. (San Jose, CA); Strum, Michael J. (San Jose, CA)

    1998-01-01

    A free standing self contained device for bonding ultra thin metallic films, such as 0.001 inch beryllium foils. The device will regulate to a predetermined load for solid state bonding when heated to a bonding temperature. The device includes a load regulating feature, whereby the expansion stresses generated for bonding are regulated and self adjusting. The load regulator comprises a pair of friction isolators with a plurality of annealed copper members located therebetween. The device, with the load regulator, will adjust to and maintain a stress level needed to successfully and economically complete a leak tight bond without damaging thin foils or other delicate components.

  2. Load regulating expansion fixture

    DOE Patents [OSTI]

    Wagner, L.M.; Strum, M.J.

    1998-12-15

    A free standing self contained device for bonding ultra thin metallic films, such as 0.001 inch beryllium foils is disclosed. The device will regulate to a predetermined load for solid state bonding when heated to a bonding temperature. The device includes a load regulating feature, whereby the expansion stresses generated for bonding are regulated and self adjusting. The load regulator comprises a pair of friction isolators with a plurality of annealed copper members located therebetween. The device, with the load regulator, will adjust to and maintain a stress level needed to successfully and economically complete a leak tight bond without damaging thin foils or other delicate components. 1 fig.

  3. Cryogenic Current Lead Analysis Model Program

    Energy Science and Technology Software Center (OSTI)

    1992-01-01

    CCLAMP was developed to provide a tool for tha analysis of superconducting or normal current leads used to supply electricity from a warm interface (usually room temperature) to a device at cryogenic temperatures. It determines the heat leak to the cryogenic connection and the mass flow of the cryogen (typically helium) for the lead and installation modelled. It may be used to thermally optimize a lead design for a particular application. The user provides relevantmore » geometry details to model the electrical (length, diameter, superconducting length) and heat exchanger design of the lead (heat transfer coefficient, heat transfer area). It has a transient analysis capability so that lead transients such as cool down, current ramping, flow disruptions, and control simulations can be performed.« less

  4. Fan-fold shielded electrical leads

    DOE Patents [OSTI]

    Rohatgi, R.R.; Cowan, T.E.

    1996-06-11

    Disclosed are fan-folded electrical leads made from copper cladded Kapton, for example, with the copper cladding on one side serving as a ground plane and the copper cladding on the other side being etched to form the leads. The Kapton is fan folded with the leads located at the bottom of the fan-folds. Electrical connections are made by partially opening the folds of the fan and soldering, for example, the connections directly to the ground plane and/or the lead. The fan folded arrangement produces a number of advantages, such as electrically shielding the leads from the environment, is totally non-magnetic, and has a very low thermal conductivity, while being easy to fabricate. 3 figs.

  5. Fan-fold shielded electrical leads

    DOE Patents [OSTI]

    Rohatgi, Rajeev R. (Mountain View, CA); Cowan, Thomas E. (Livermore, CA)

    1996-01-01

    Fan-folded electrical leads made from copper cladded Kapton, for example, with the copper cladding on one side serving as a ground plane and the copper cladding on the other side being etched to form the leads. The Kapton is fan folded with the leads located at the bottom of the fan-folds. Electrical connections are made by partially opening the folds of the fan and soldering, for example, the connections directly to the ground plane and/or the lead. The fan folded arrangement produces a number of advantages, such as electrically shielding the leads from the environment, is totally non-magnetic, and has a very low thermal conductivity, while being easy to fabricate.

  6. November 17, 2009 HSS/Union Lead Checkpoint Meeting on Integrated Collaborative Oversight - Overview

    Energy Savers [EERE]

    Meeting Points HSS Changes to Safety Structure/ HSS Integrated Collaborative Oversight Process * HSS tasked by the Deputy Secretary to lead a collaborative evaluation of, and identify options for, improving regulation/oversight of safety at DOE facilities in response to concerns expressed by the DOE Laboratories and Contractors of stringent regulations impairing competitiveness and impacting resources. * HSS Path Forward: -- Strengthen oversight function [i.e., increase nuclear safety and

  7. Method for measuring lead concentrations in blood

    DOE Patents [OSTI]

    Nogar, Nicholas S. (Los Alamos, NM)

    2001-01-01

    Method for measuring lead concentrations in blood. The present invention includes the use of resonant laser ablation to analyze .ltoreq.1 .mu.L (or equivalent mass) samples of blood for lead content. A typical finger prick, for example, yields about 10 .mu.L. Solid samples may also readily be analyzed by resonant laser ablation. The sample is placed on a lead-free, electrically conducting substrate and irradiated with a single, focused laser beam which simultaneously vaporizes, atomizes, and resonantly ionizes an analyte of interest in a sample. The ions are then sorted, collected and detected using a mass spectrometer.

  8. HUD`s lead-based paint activities

    SciTech Connect (OSTI)

    Morony, R.

    1994-12-31

    Title X of Public Law 102-550 is a major piece of legislation for the Department having to do with lead-based paint. It changes the way the Department is going to be doing all of its work with lead-based paint in all areas except public housing. It is a mandate from Congress for a great deal of change. It is going to cause revisions in the regulations. Title X authorizes a grant program to State and local governments for the abatement of lead-based paint in low income, privately owned housing. This is an area that has not gotten attention from the Federal government before. The first series of grants have been awarded, some $46 million, to six States, three cities, and one county. The grantees have been selected for $91 million that will go to 19 winners. They received 63 applications, again from State and local governments, again for privately owned housing. There is a third grant series in this fiscal year. The applications for the $142 million are due July 5, 1994. Again, HUD is looking at privately owned housing. This is not housing that is, in most cases, federally assisted in any way.

  9. The risk of lead toxicity in homes with lead paint hazard

    SciTech Connect (OSTI)

    Schwartz, J.; Levin, R. )

    1991-02-01

    While lead paint has long been known to be a major source of lead poisoning, only a few small epidemiologic studies have attempted to assess directly the relative risk of lead poisoning due to the presence of lead paint. Using data from over 200,000 screening tests of children in the city of Chicago performed between 1976 and 1980, the relative risks can be quantified for children living in a major urban area. Lead paint was found to be a significant predictor of the probability of a child having lead toxicity. As expected, the reduction in leaded gasoline sales during the period reduced mean blood lead levels and increased the percentage of lead toxic children whose toxicity could be attributed to paint lead. Poisson regression models indicated that with the elimination of leaded gasoline, the relative risk of lead toxicity given lead paint exposure was 5.70 (95% CI, 4.13-7.86) during the winter and fall. The relative risk rose to 12.81 (95% CI, 7.33-22.4) in the spring and 15.8 (95% CI, 8.90-28.1) in the summer, probably due to increased exposure to window wells.

  10. Replica amplification of nucleic acid arrays

    DOE Patents [OSTI]

    Church, George M.; Mitra, Robi D.

    2010-08-31

    Disclosed are improved methods of making and using immobilized arrays of nucleic acids, particularly methods for producing replicas of such arrays. Included are methods for producing high density arrays of nucleic acids and replicas of such arrays, as well as methods for preserving the resolution of arrays through rounds of replication. Also included are methods which take advantage of the availability of replicas of arrays for increased sensitivity in detection of sequences on arrays. Improved methods of sequencing nucleic acids immobilized on arrays utilizing single copies of arrays and methods taking further advantage of the availability of replicas of arrays are disclosed. The improvements lead to higher fidelity and longer read lengths of sequences immobilized on arrays. Methods are also disclosed which improve the efficiency of multiplex PCR using arrays of immobilized nucleic acids.

  11. Fatty acid analogs

    DOE Patents [OSTI]

    Elmaleh, David R. (Newton Center, MA); Livni, Eli (Brookline, MA)

    1985-01-01

    In one aspect, a radioactively labeled analog of a fatty acid which is capable of being taken up by mammalian tissue and which exhibits an in vivo beta-oxidation rate below that with a corresponding radioactively labeled fatty acid.

  12. Pressure reducing regulator

    DOE Patents [OSTI]

    Whitehead, John C. (Davis, CA); Dilgard, Lemoyne W. (Willits, CA)

    1995-01-01

    A pressure reducing regulator that controls its downstream or outlet pressure to a fixed fraction of its upstream or inlet pressure. The regulator includes a housing which may be of a titanium alloy, within which is located a seal or gasket at the outlet end which may be made of annealed copper, a rod, and piston, each of which may be made of high density graphite. The regulator is insensitive to temperature by virtue of being without a spring or gas sealed behind a diaphragm, and provides a reference for a system in which it is being used. The rod and piston of the regulator are constructed, for example, to have a 1/20 ratio such that when the downstream pressure is less than 1/20 of the upstream pressure the regulator opens and when the downstream pressure exceeds 1/20 of the upstream pressure the regulator closes.

  13. Pressure reducing regulator

    DOE Patents [OSTI]

    Whitehead, J.C.; Dilgard, L.W.

    1995-10-10

    A pressure reducing regulator that controls its downstream or outlet pressure to a fixed fraction of its upstream or inlet pressure is disclosed. The regulator includes a housing which may be of a titanium alloy, within which is located a seal or gasket at the outlet end which may be made of annealed copper, a rod, and piston, each of which may be made of high density graphite. The regulator is insensitive to temperature by virtue of being without a spring or gas sealed behind a diaphragm, and provides a reference for a system in which it is being used. The rod and piston of the regulator are constructed, for example, to have a 1/20 ratio such that when the downstream pressure is less than 1/20 of the upstream pressure the regulator opens and when the downstream pressure exceeds 1/20 of the upstream pressure the regulator closes. 10 figs.

  14. Lead Hero Limited | Open Energy Information

    Open Energy Info (EERE)

    Hero Limited Jump to: navigation, search Name: Lead Hero Limited Place: China Product: China-based company that holds a 100% interest in XiAn Lv Jing and a 15.05% interest in...

  15. INEEL Lead Recycling in a Moratorium Environment

    SciTech Connect (OSTI)

    Kooda, K. E.; Galloway, K.; McCray, C. W.; Aitken, D. W.

    2003-02-26

    Since 1999, the Idaho National Engineering and Environmental Laboratory (INEEL) Lead Project successfully recycled over 700,000 pounds of excess INEEL lead to the private sector. On February 14, 2000, the Secretary of Energy, Bill Richardson, formalized the January 12, 2000, moratorium on recycling radioactive scrap metal that prevented the unrestricted release of recycled scrap metals to the private sector. This moratorium created significant problems for the INEEL lead recycling program and associated plans; however, through the cooperative efforts of the INEEL and Idaho State University as well as innovative planning and creative thinking the recycling issues were resolved. This collaboration has recycled over 160,000 pounds of excess lead to Idaho State University with a cost savings of over $.5M.

  16. INEEL Lead Recycling in a Moratorium Environment

    SciTech Connect (OSTI)

    Kooda, Kevin Evan; Mc Cray, Casey William; Aitken, Darren William; Galloway, Kelly

    2003-02-01

    Since 1999, the Idaho National Engineering and Environmental Laboratory (INEEL) Lead Project successfully recycled over 700,000 pounds of excess INEEL lead to the private sector. On February 14, 2000, the Secretary of Energy, Bill Richardson, formalized the January 12, 2000, moratorium on recycling radioactive scrap metal that prevented the unrestricted release of recycled scrap metals to the private sector. This moratorium created significant problems for the INEEL lead recycling program and associated plans; however, through the cooperative efforts of the INEEL and Idaho State University as well as innovative planning and creative thinking the recycling issues were resolved. This collaboration has recycled over 160,000 pounds of excess lead to Idaho State University with a cost savings of over $.5M.

  17. Corrosion by liquid lead and lead-bismuth: experimental results review and analysis

    SciTech Connect (OSTI)

    Zhang, Jinsuo

    2008-01-01

    Liquid metal technologies for liquid lead and lead-bismuth alloy are under wide investigation and development for advanced nuclear energy systems and waste transmutation systems. Material corrosion is one of the main issues studied a lot recently in the development of the liquid metal technology. This study reviews corrosion by liquid lead and lead bismuth, including the corrosion mechanisms, corrosion inhibitor and the formation of the protective oxide layer. The available experimental data are analyzed by using a corrosion model in which the oxidation and scale removal are coupled. Based on the model, long-term behaviors of steels in liquid lead and lead-bismuth are predictable. This report provides information for the selection of structural materials for typical nuclear reactor coolant systems when selecting liquid lead or lead bismuth as heat transfer media.

  18. Measurement of the production of neighbouring jets in lead-lead...

    Office of Scientific and Technical Information (OSTI)

    Measurement of the production of neighbouring jets in lead-lead collisions at sNN2.76 TeV with the ATLAS detector Citation Details In-Document Search Title: Measurement of the...

  19. Nick Wright Named Advanced Technologies Group Lead

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Nick Wright Named Advanced Technologies Group Lead Nick Wright Named Advanced Technologies Group Lead February 4, 2013 Nick Nick Wright has been named head of the National Energy Research Scientific Computing Center's (NERSC) Advanced Technologies Group (ATG), which focuses on understanding the requirements of current and emerging applications to make choices in hardware design and programming models that best serve the science needs of NERSC users. ATG specializes in benchmarking, system

  20. NERSC seeks Computational Systems Group Lead

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    seeks Computational Systems Group Lead NERSC seeks Computational Systems Group Lead January 6, 2011 by Katie Antypas Note: This position is now closed. The Computational Systems Group provides production support and advanced development for the supercomputer systems at NERSC. Manage the Computational Systems Group (CSG) which provides production support and advanced development for the supercomputer systems at NERSC (National Energy Research Scientific Computing Center). These systems, which

  1. Plant fatty acid hydroxylases

    DOE Patents [OSTI]

    Somerville, Chris (Portola Valley, CA); Broun, Pierre (Burlingame, CA); van de Loo, Frank (Lexington, KY)

    2001-01-01

    This invention relates to plant fatty acyl hydroxylases. Methods to use conserved amino acid or nucleotide sequences to obtain plant fatty acyl hydroxylases are described. Also described is the use of cDNA clones encoding a plant hydroxylase to produce a family of hydroxylated fatty acids in transgenic plants. In addition, the use of genes encoding fatty acid hydroxylases or desaturases to alter the level of lipid fatty acid unsaturation in transgenic plants is described.

  2. PRODUCTION OF TRIFLUOROACETIC ACID

    DOE Patents [OSTI]

    Haworth, W.N.; Stacey, M.

    1949-07-19

    A method is given for the production of improved yields of trifluoroacetic acid. The compound is prepared by oxidizing m-aminobenzotrifluoride with an alkali metal or alkaline earth metal permanganate at a temperature in the range of 80 deg C to 100 deg C while dissolved ln a mixture of water with glacial acetic acid and/or trifluoroacetic acid. Preferably a mixture of water and trifluoroacetic acid ls used as the solvent.

  3. Policy and Regulations | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Regulations Policy and Regulations map-1019833_960_720.jpg

  4. Resources for Utility Regulators

    SciTech Connect (OSTI)

    SEE Action

    2012-06-01

    Provides a summary of State and Local Energy Efficiency Action Network (SEE Action) information resources available to utility regulators, organized by topic.

  5. Removal of Radioactive Nuclides from Mo-99 Acidic Liquid Waste - 13027

    SciTech Connect (OSTI)

    Hsiao, Hsien-Ming; Pen, Ben-Li

    2013-07-01

    About 200 liters highly radioactive acidic liquid waste originating from Mo-99 production was stored at INER (Institute of Nuclear Energy Research). A study regarding the treatment of the radioactive acidic liquid waste was conducted to solve storage-related issues and allow discharge of the waste while avoiding environmental pollution. Before discharging the liquid waste, the acidity, NO{sub 3}{sup -} and Hg ions in high concentrations, and radionuclides must comply with environmental regulations. Therefore, the treatment plan was to neutralize the acidic liquid waste, remove key radionuclides to reduce the dose rate, and then remove the nitrate and mercury ions. Bench tests revealed that NaOH is the preferred solution to neutralize the high acidic waste solution and the pH of solution must be adjusted to 9?11 prior to the removal of nuclides. Significant precipitation was produced when the pH of solution reached 9. NaNO{sub 3} was the major content in the precipitate and part of NaNO{sub 3} was too fine to be completely collected by filter paper with a pore size of approximately 3 ?m. The residual fine particles remaining in solution therefore blocked the adsorption column during operation. Two kinds of adsorbents were employed for Cs-137 and a third for Sr-90 removal to minimize cost. For personnel radiation protection, significant lead shielding was required at a number of points in the process. The final process design and treatment facilities successfully treated the waste solutions and allowed for environmentally compliant discharge. (authors)

  6. Cleavage of nucleic acids

    DOE Patents [OSTI]

    Prudent, James R. (Madison, WI); Hall, Jeff G. (Waunakee, WI); Lyamichev, Victor I. (Madison, WI); Brow; Mary Ann D. (Madison, WI); Dahlberg, James E. (Madison, WI)

    2010-11-09

    The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.

  7. Cleavage of nucleic acids

    DOE Patents [OSTI]

    Prudent, James R. (Madison, WI); Hall, Jeff G. (Madison, WI); Lyamichev, Victor I. (Madison, WI); Brow, Mary Ann D. (Madison, WI); Dahlberg, James E. (Madison, WI)

    2000-01-01

    The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.

  8. Nucleic acid detection compositions

    DOE Patents [OSTI]

    Prudent, James R. (Madison, WI); Hall, Jeff G. (Madison, WI); Lyamichev, Victor I. (Madison, WI); Brow, Mary Ann (Madison, WI); Dahlberg, James L. (Madison, WI)

    2008-08-05

    The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.

  9. Nucleic acid detection assays

    DOE Patents [OSTI]

    Prudent, James R.; Hall, Jeff G.; Lyamichev, Victor I.; Brow, Mary Ann; Dahlberg, James E.

    2005-04-05

    The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.

  10. Cleavage of nucleic acids

    DOE Patents [OSTI]

    Prudent, James R. (Madison, WI); Hall, Jeff G. (Madison, WI); Lyamichev, Victor L. (Madison, WI); Brow, Mary Ann D. (Madison, WI); Dahlberg, James E. (Madison, WI)

    2007-12-11

    The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.

  11. WIPP Documents - Federal Regulations

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Federal Regulations 40 CFR Part 191 Environmental radiation protection standards for management and disposal of spent nuclear fuel, high-level and transuranic radioactive wastes. 40 CFR Part 194 Criteria for the certification and re-certification of the Waste Isolation Pilot Plant's compliance with the 40 CFR Part 191 disposal regulations.

  12. Nucleic acid detection kits

    DOE Patents [OSTI]

    Hall, Jeff G.; Lyamichev, Victor I.; Mast, Andrea L.; Brow, Mary Ann; Kwiatkowski, Robert W.; Vavra, Stephanie H.

    2005-03-29

    The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof. The present invention further relates to methods and devices for the separation of nucleic acid molecules based on charge. The present invention also provides methods for the detection of non-target cleavage products via the formation of a complete and activated protein binding region. The invention further provides sensitive and specific methods for the detection of nucleic acid from various viruses in a sample.

  13. Properly engineer lead paint removal projects

    SciTech Connect (OSTI)

    Kaelin, A.B.

    1996-01-01

    Deciding how to mitigate the hazards during lead paint removal is complex and requires consideration of many variables. Assessment of public health risk, environmental impact, and emissions potential of the operations must be considered. Additionally, the removal technique, containment system, and monitoring criteria must be developed. This article presents an integrated approach to identifying lead hazards, assessing risks to workers, the environment, and the public, developing the appropriate maintenance strategy, and selecting paint removal and containment systems. Also considered are guidelines for selecting a third party to design the overall project. This approach is based on a decision path that provides criteria for project assessment in an orderly fashion. The design of lead paint management projects in industrial applications requires consideration of the variables shown in the decision path.

  14. Process for the preparation of lactic acid and glyceric acid

    DOE Patents [OSTI]

    Jackson, James E [Haslett, MI; Miller, Dennis J [Okemos, MI; Marincean, Simona [Dewitt, MI

    2008-12-02

    Hexose and pentose monosaccharides are degraded to lactic acid and glyceric acid in an aqueous solution in the presence of an excess of a strongly anionic exchange resin, such as AMBERLITE IRN78 and AMBERLITE IRA400. The glyceric acid and lactic acid can be separated from the aqueous solution. Lactic acid and glyceric acid are staple articles of commerce.

  15. L I NATIONAL' LEAD COMPANY OF OHIO

    Office of Legacy Management (LM)

    L I NATIONAL' LEAD COMPANY OF OHIO tJw HEALTH AND SAFETY DI"ISION - ANALITICIL DEPT. ANALYTICAL DATA SHEET _I . . NATIONAL LEAD COMPANY O F OHIO HEALTH AND SAFETY DIY1SION - ANALYTICAL DEPT. ANALYTICAL DATA SHEET NATIONA-i LEn' D COMPANY OF OHIO HEALTH AND SAFETY Dl"lSlDN - m4ALITICAL DEPT. ANALYTICAL DATA SHEET NO. I DlSTRlBUTlON OF COPIES I I A,w,lytlc.al Loboratorr (RBCORD COPI) 2 Induswlol Hvalen. B Rodhtlon Dept. 3 1 Water Trsotmmt Plant c=.z w&w hnp,., Only, - . _. NATIONAL

  16. Coordination chemistry of two heavy metals: I, Ligand preferences in lead(II) complexation, toward the development of therapeutic agents for lead poisoning: II, Plutonium solubility and speciation relevant to the environment

    SciTech Connect (OSTI)

    Neu, M.P.

    1993-11-01

    The coordination chemistry and solution behavior of the toxic ions lead(II) and plutonium(IV, V, VI) have been investigated. The ligand pK{sub a}s and ligand-lead(II) stability constants of one hydroxamic acid and four thiohydroaxamic acids were determined. Solution thermodynamic results indicate that thiohydroxamic acids are more acidic and slightly better lead chelators than hydroxamates, e.g., N-methylthioaceto-hydroxamic acid, pK{sub a} = 5.94, log{beta}{sub 120} = 10.92; acetohydroxamic acid, pK{sub a} = 9.34, log{beta}{sub l20} = 9.52. The syntheses of lead complexes of two bulky hydroxamate ligands are presented. The X-ray crystal structures show the lead hydroxamates are di-bridged dimers with irregular five-coordinate geometry about the metal atom and a stereochemically active lone pair of electrons. Molecular orbital calculations of a lead hydroxamate and a highly symmetric pseudo octahedral lead complex were performed. The thermodynamic stability of plutonium(IV) complexes of the siderophore, desferrioxamine B (DFO), and two octadentate derivatives of DFO were investigated using competition spectrophotometric titrations. The stability constant measured for the plutonium(IV) complex of DFO-methylterephthalamide is log{beta}{sub 110} = 41.7. The solubility limited speciation of {sup 242}Pu as a function of time in near neutral carbonate solution was measured. Individual solutions of plutonium in a single oxidation state were added to individual solutions at pH = 6.0, T = 30.0, 1.93 mM dissolved carbonate, and sampled over intervals up to 150 days. Plutonium solubility was measured, and speciation was investigated using laser photoacoustic spectroscopy and chemical methods.

  17. Microorganisms for producing organic acids

    DOE Patents [OSTI]

    Pfleger, Brian Frederick; Begemann, Matthew Brett

    2014-09-30

    Organic acid-producing microorganisms and methods of using same. The organic acid-producing microorganisms comprise modifications that reduce or ablate AcsA activity or AcsA homolog activity. The modifications increase tolerance of the microorganisms to such organic acids as 3-hydroxypropionic acid, acrylic acid, propionic acid, lactic acid, and others. Further modifications to the microorganisms increase production of such organic acids as 3-hydroxypropionic acid, lactate, and others. Methods of producing such organic acids as 3-hydroxypropionic acid, lactate, and others with the modified microorganisms are provided. Methods of using acsA or homologs thereof as counter-selectable markers are also provided.

  18. Born energy, acid-base equilibrium, structure and interactions of end-grafted weak polyelectrolyte layers

    SciTech Connect (OSTI)

    Nap, R. J.; Tagliazucchi, M.; Szleifer, I.

    2014-01-14

    This work addresses the effect of the Born self-energy contribution in the modeling of the structural and thermodynamical properties of weak polyelectrolytes confined to planar and curved surfaces. The theoretical framework is based on a theory that explicitly includes the conformations, size, shape, and charge distribution of all molecular species and considers the acid-base equilibrium of the weak polyelectrolyte. Namely, the degree of charge in the polymers is not imposed but it is a local varying property that results from the minimization of the total free energy. Inclusion of the dielectric properties of the polyelectrolyte is important as the environment of a polymer layer is very different from that in the adjacent aqueous solution. The main effect of the Born energy contribution on the molecular organization of an end-grafted weak polyacid layer is uncharging the weak acid (or basic) groups and consequently decreasing the concentration of mobile ions within the layer. The magnitude of the effect increases with polymer density and, in the case of the average degree of charge, it is qualitatively equivalent to a small shift in the equilibrium constant for the acid-base equilibrium of the weak polyelectrolyte monomers. The degree of charge is established by the competition between electrostatic interactions, the polymer conformational entropy, the excluded volume interactions, the translational entropy of the counterions and the acid-base chemical equilibrium. Consideration of the Born energy introduces an additional energetic penalty to the presence of charged groups in the polyelectrolyte layer, whose effect is mitigated by down-regulating the amount of charge, i.e., by shifting the local-acid base equilibrium towards its uncharged state. Shifting of the local acid-base equilibrium and its effect on the properties of the polyelectrolyte layer, without considering the Born energy, have been theoretically predicted previously. Account of the Born energy leads to systematic, but in general small, corrections to earlier theoretical predictions describing the behavior of weak polyelectrolyte layers. However, polyelectrolyte uncharging results in a decrease in the concentration of counterions and inclusion of the Born Energy can result in a substantial decrease of the counterion concentration. The effect of considering the Born energy contribution is explored for end-grafted weak polyelectrolyte layers by calculating experimental observables which are known to depend on the presence of charges within the polyelectrolyte layer: inclusion of the Born energy contribution leads to a decrease in the capacitance of polyelectrolyte-modified electrodes, a decrease of conductivity of polyelectrolyte-modified nanopores and an increase in the repulsion exerted by a planar polyelectrolyte layer confined by an opposing wall.

  19. Worker lead exposures during renovation of homes with lead-based paint

    SciTech Connect (OSTI)

    Sussell, A.; Gittleman, J.; Singal, M.

    1998-11-01

    The authors evaluated lead exposures among full-time home renovators and part-time volunteers working primarily in pre-1960 homes with lead-based paint. Potentially hazardous lead exposures were measured during two tasks: exterior dry scraping and wet scraping. Maximum exposures were 120 and 63 {micro}g/m{sup 3}, respectively. Exposures during other tasks, including general repair, weatherization, exterior scraping/painting, window replacement, demolition, and plumbing, were low, as were all 13 full-shift personal exposures. Blood lead levels for full-time workers ranged up to 17.5 {micro}g/dl, with a GM of 5.2 {micro}g/dl; the GM for volunteers was 3.2 {micro}g/dl. All of the paint samples collected from work surfaces had detectable amounts of lead, with 65% of the work surfaces tested having an average lead concentration of >0.5%.

  20. Lead-203 as a label for radioimaging

    DOE Patents [OSTI]

    Srivastava, Suresh C.; Meinken, George E.

    1990-01-01

    A radiopharmaceutical composition comprising a radioactive isotope of lead (Pb-203) in combination with a pharmaceutical or an antibody or antibody fragment and a bifunctional chelating agent. These compositions are especially useful in the imaging and diagnosis of tumors and tumor metastases.

  1. Hanford Leads the Way for Greener Classrooms

    Broader source: Energy.gov [DOE]

    EM’s Richland Operations Office and contractor Mission Support Alliance (MSA) are leading the way to greener classrooms by developing a totally paperless class at the HAMMER Federal Training Facility at the Hanford site. MSA manages HAMMER on behalf of EM.

  2. Of Refrigerators & Regulations

    Broader source: Energy.gov [DOE]

    Editor's Note: This entry has been cross-posted from The White House Blog. The President took a moment during his speech to put the debate over regulation in a different perspective.

  3. Recovery of organic acids

    DOE Patents [OSTI]

    Verser, Dan W. (Menlo Park, CA); Eggeman, Timothy J. (Lakewood, CO)

    2011-11-01

    A method is disclosed for the recovery of an organic acid from a dilute salt solution in which the cation of the salt forms an insoluble carbonate salt. A tertiary amine and CO.sub.2 are introduced to the solution to form the insoluble carbonate salt and a complex between the acid and an amine. A water immiscible solvent, such as an alcohol, is added to extract the acid/amine complex from the dilute salt solution to a reaction phase. The reaction phase is continuously dried and a product between the acid and the solvent, such as an ester, is formed.

  4. Recovery of organic acids

    DOE Patents [OSTI]

    Verser, Dan W. (Golden, CO); Eggeman, Timothy J. (Lakewood, CO)

    2009-10-13

    A method is disclosed for the recovery of an organic acid from a dilute salt solution in which the cation of the salt forms an insoluble carbonate salt. A tertiary amine and CO.sub.2 are introduced to the solution to form the insoluble carbonate salt and a complex between the acid and an amine. A water immiscible solvent, such as an alcohol, is added to extract the acid/amine complex from the dilute salt solution to a reaction phase. The reaction phase is continuously dried and a product between the acid and the solvent, such as an ester, is formed.

  5. Reversible Acid Gas Capture

    ScienceCinema (OSTI)

    Dave Heldebrant

    2012-12-31

    Pacific Northwest National Laboratory scientist David Heldebrant demonstrates how a new process called reversible acid gas capture works to pull carbon dioxide out of power plant emissions.

  6. Lead magnesium niobate actuator for micropositioning

    DOE Patents [OSTI]

    Swift, C.D.; Bergum, J.W.

    1994-10-25

    An improved lead magnesium niobate actuator is disclosed comprising a cylindrical lead magnesium niobate crystal stack mounted in a cylindrical casing wherein a bias means, such as one or more belleville washers, is located between one end of the crystal stack and a partially closed end of the casing; and adjustment means are provided which bear against the opposite end of the crystal stack, whereby an adjustable compressive force is constantly applied against the crystal stack, whether the crystal stack is actuated in an extended position, or is in an unactuated contracted position. In a preferred embodiment, cooling ports are provided for the circulation of coolant in the actuator to cool the crystal stack, and provision is made for removal and replacement of the crystal stack without disconnecting the actuator from the external device being actuated. 3 figs.

  7. Lead magnesium niobate actuator for micropositioning

    DOE Patents [OSTI]

    Swift, Charles D. (Livermore, CA); Bergum, John W. (Concord, CA)

    1994-01-01

    An improved lead magnesium niobate actuator is disclosed comprising a cylindrical lead magnesium niobate crystal stack mounted in a cylindrical casing wherein a bias means, such as one or more belleville washers, is located between one end of the crystal stack and a partially closed end of the casing; and adjustment means are provided which bear against the opposite end of the crystal stack, whereby an adjustable compressive force is constantly applied against the crystal stack, whether the crystal stack is actuated in an extended position, or is in an unactuated contracted position. In a preferred embodiment, cooling ports are provided for the circulation of coolant in the actuator to cool the crystal stack, and provision is made for removal and replacement of the crystal stack without disconnecting the actuator from the external device being actuated.

  8. Fermilab | Science | Particle Accelerators | Leading Accelerator Technology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Leading Accelerator Technology photo From blueprint to construction, Fermilab scientists and engineers develop particle accelerators to produce beams to take particle physics to the next level, collaborating with scientists and laboratories around the world to help build these complex machines. Researchers build accelerators to be efficient and robust along every step of the particle beam's path, from the time it's born to its termination on target. The machines themselves must be efficient,

  9. Kazmerski Leads National Center for Solar Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Kazmerski Leads National Center for Solar Research For more information contact: e:mail: Public Affairs Golden, Colo., Dec. 1, 1998 — The future of solar energy got brighter today when Larry Kazmerski started his new position as director of the National Center for Photovoltaics (NCPV). Thanks to his shining 21-year research career at the National Renewable Energy Laboratory (NREL), he was selected after a nationwide search. The U.S. Department of Energy created the NCPV in 1996 to provide a

  10. Mutant fatty acid desaturase

    DOE Patents [OSTI]

    Shanklin, John; Cahoon, Edgar B.

    2004-02-03

    The present invention relates to a method for producing mutants of a fatty acid desaturase having a substantially increased activity towards fatty acid substrates with chains containing fewer than 18 carbons relative to an unmutagenized precursor desaturase having an 18 carbon atom chain length substrate specificity. The method involves inducing one or more mutations in the nucleic acid sequence encoding the precursor desaturase, transforming the mutated sequence into an unsaturated fatty acid auxotroph cell such as MH13 E. coli, culturing the cells in the absence of supplemental unsaturated fatty acids, thereby selecting for recipient cells which have received and which express a mutant fatty acid desaturase with an elevated specificity for fatty acid substrates having chain lengths of less than 18 carbon atoms. A variety of mutants having 16 or fewer carbon atom chain length substrate specificities are produced by this method. Mutant desaturases produced by this method can be introduced via expression vectors into prokaryotic and eukaryotic cells and can also be used in the production of transgenic plants which may be used to produce specific fatty acid products.

  11. Unique Auxin Regulation Mechanism Discovered

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Unique Auxin Regulation Mechanism Discovered Print The plant hormone auxin regulates many plant growth and development processes, including shoot growth, root branching, fruit...

  12. Unique Auxin Regulation Mechanism Discovered

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Auxin Regulation Mechanism Discovered Print Wednesday, 29 August 2007 00:00 The plant hormone auxin regulates many plant growth and development processes, including shoot growth,...

  13. Thermal spray vitrification process for the removal of lead oxide contained in organic paints

    SciTech Connect (OSTI)

    Karthikeyan, J.; Chen, J.; Bancke, G.A.; Herman, H.; Berndt, C.C.; Breslin, V.T.

    1995-12-31

    The US Environmental Protection Agency (US-EPA) regulations have necessitated the removal and containment of toxic lead from lead oxide containing paints. The Thermal Spray Vitrification Process (TSVP) is a novel technique in which a glass powder of appropriate composition is flame sprayed onto the painted surface to achieve removal and vitrification of the lead. Two different glass systems, i.e., alkali silicate and ferrous silicate, were chosen for detailed study. Appropriate amounts of raw materials were mixed, fused, quenched, ground and sieved to obtain the spray quality powders. Grit blasted mild steel coupons were used as test substrates for the spray parameter optimization studies; while those coupons with lead oxide containing organic paint were used for the lead removal experiments. The powders and deposits were investigated using Microtrac particle size analysis (for powders), optical microscopy, XRD and SEM. The remnant lead in the panel was measured using a specially prepared X-Ray Fluorescence (XRF) system. The lead leach rate was recorded as per US-EPA approved Toxicity Characteristic Leaching Procedure (TCLP). The results of this study have shown that lead oxide can be successfully removed form the paint by flame spraying a maximum of three layers of glass onto the painted surface. It is possible to obtain much higher lead removal rate with ferrous silicate glass as compared to alkali silicate glass is much higher than the ferrous silicate glass. The in situ vitrification has not been completely optimized; however, the lead containing glass coating can be remelted in situ or on site to enhance the vitrification of the lead which had been absorbed in the glass coating.

  14. Sex-based differences in gene expression in hippocampus following postnatal lead exposure

    SciTech Connect (OSTI)

    Schneider, J.S., E-mail: jay.schneider@jefferson.edu; Anderson, D.W.; Sonnenahalli, H.; Vadigepalli, R.

    2011-10-15

    The influence of sex as an effect modifier of childhood lead poisoning has received little systematic attention. Considering the paucity of information available concerning the interactive effects of lead and sex on the brain, the current study examined the interactive effects of lead and sex on gene expression patterns in the hippocampus, a structure involved in learning and memory. Male or female rats were fed either 1500 ppm lead-containing chow or control chow for 30 days beginning at weaning.Blood lead levels were 26.7 {+-} 2.1 {mu}g/dl and 27.1 {+-} 1.7 {mu}g/dl for females and males, respectively. The expression of 175 unique genes was differentially regulated between control male and female rats. A total of 167 unique genes were differentially expressed in response to lead in either males or females. Lead exposure had a significant effect without a significant difference between male and female responses in 77 of these genes. In another set of 71 genes, there were significant differences in male vs. female response. A third set of 30 genes was differentially expressed in opposite directions in males vs. females, with the majority of genes expressed at a lower level in females than in males. Highly differentially expressed genes in males and females following lead exposure were associated with diverse biological pathways and functions. These results show that a brief exposure to lead produced significant changes in expression of a variety of genes in the hippocampus and that the response of the brain to a given lead exposure may vary depending on sex. - Highlights: > Postnatal lead exposure has a significant effect on hippocampal gene expression patterns. > At least one set of genes was affected in opposite directions in males and females. > Differentially expressed genes were associated with diverse biological pathways.

  15. Reviving regulation - and antitrust

    SciTech Connect (OSTI)

    Shepherd, W.G.

    1994-06-01

    The ills of utility regulation have been overstated by interested players and at least some academics. One can have the best features of both competition and regulation by a paradigm that combines some regulation with stronger antitrust enforcement. It is now obvious that the success of deregulation actually depends crucially on whether antitrust policy is effective in preventing monopoly. In fact, antitrust policies have been extremely weak since 1980, under a deliberate Reagan administration withdrawal of enforcement. Where deregulation has led to market dominance, which antitrust cannot well cure, the policy changes of the 1980`s may have created costly and irreversible mistakes in a number of major sectors. Yet fast-paced events are currently creating a frenzy of even more deregulation, supposedly to fit new {open_quotes}revolutions{close_quotes} in technology and the impacts of large mergers. Instead it is time for particular caution in electricity.

  16. Lead Slowing Down Spectrometer Status Report

    SciTech Connect (OSTI)

    Warren, Glen A.; Anderson, Kevin K.; Bonebrake, Eric; Casella, Andrew M.; Danon, Yaron; Devlin, M.; Gavron, Victor A.; Haight, R. C.; Imel, G. R.; Kulisek, Jonathan A.; O'Donnell, J. M.; Weltz, Adam

    2012-06-07

    This report documents the progress that has been completed in the first half of FY2012 in the MPACT-funded Lead Slowing Down Spectrometer project. Significant progress has been made on the algorithm development. We have an improve understanding of the experimental responses in LSDS for fuel-related material. The calibration of the ultra-depleted uranium foils was completed, but the results are inconsistent from measurement to measurement. Future work includes developing a conceptual model of an LSDS system to assay plutonium in used fuel, improving agreement between simulations and measurement, design of a thorium fission chamber, and evaluation of additional detector techniques.

  17. Novel lead-iron phosphate glass

    DOE Patents [OSTI]

    Boatner, L.A.; Sales, B.C.

    1989-07-11

    The invention described and claimed in the specification relates to the discovery that effective addition of Fe[sub 2]O[sub 3] to a lead phosphate glass results in a glass having enhanced chemical durability and physical stability, and consists essentially of the glass resulting from melting a mixture consisting essentially of, in weight percent, 40--66 percent PbO, 30--55 percent P[sub 2]O[sub 5] and an effective concentration up to 12 percent Fe[sub 2]O[sub 3].

  18. Events leading to the Manhattan Project

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    leading to the Manhattan Project This is the third in a series of articles on the unique history of Y-12. A series of significant events across the world were precursors to the Manhattan Project and Y-12. The basic building blocks and mechanisms of atomic energy were discovered over the first 40 years of the twentieth century. The basic knowledge of physics was greatly expanded around the turn of the century when scientists began to understand the nature of atoms. French physicist Pierre Curie

  19. Non-lead hollow point bullet

    DOE Patents [OSTI]

    Vaughn, Norman L. (Knoxville, TN); Lowden, Richard A. (Clinton, TN)

    2003-04-15

    The non-lead hollow point bullet of the instant invention comprises a mixed construction slug further comprising, a monolithic metal insert having a tapered (preferred conical) hollow point tip and a tapered (preferred conical) tail protrusion, and an unsintered powdered metal composite core in tandem alignment with the insert. The core has a hollow tapered (preferred conical) cavity tip portion coupled with the tapered (preferred conical) tail protrusion on the insert. An open tip jacket envelops at least a portion of the insert and the core. The jacket is swaged at the open tip.

  20. SUMMARY OF REGULATIONS IMPLEMENTING FEDERAL POWER ACT SECTION 216 |

    Energy Savers [EERE]

    Department of Energy SUMMARY OF REGULATIONS IMPLEMENTING FEDERAL POWER ACT SECTION 216 SUMMARY OF REGULATIONS IMPLEMENTING FEDERAL POWER ACT SECTION 216 The Energy Policy Act of 2005 added section 216(h) to the Federal Power Act providing for the Department of Energy to act as the lead agency for coordinating all applicable Federal authorizations and related environmental reviews required under Federal law in order to site an electric transmission facility. The Act authorized DOE to issue

  1. Nonaqueous solution synthesis process for preparing oxide powders of lead zirconate titanate and related materials

    DOE Patents [OSTI]

    Voigt, J.A.; Sipola, D.L.; Tuttle, B.A.; Anderson, M.T.

    1999-06-01

    A process is disclosed for producing powders of perovskite-type compounds which comprises mixing a metal alkoxide solution with a lead acetate solution to form a homogeneous, clear metal solution, adding an oxalic acid/n-propanol solution to this metal solution to form an easily filterable, free-flowing precursor powder and then calcining this powder. This process provides fine perovskite-phase powders with ferroelectric properties which are particularly useful in a variety of electronic applications. 4 figs.

  2. Nonaqueous solution synthesis process for preparing oxide powders of lead zirconate titanate and related materials

    DOE Patents [OSTI]

    Voigt, James A. (Corrales, NM); Sipola, Diana L. (Albuquerque, NM); Tuttle, Bruce A. (Albuquerque, NM); Anderson, Mark T. (Woodbury, MN)

    1999-01-01

    A process for producing powders of perovskite-type compounds which comprises mixing a metal alkoxide solution with a lead acetate solution to form a homogeneous, clear metal solution, adding an oxalic acid/n-propanol solution to this metal solution to form an easily filterable, free-flowing precursor powder and then calcining this powder. This process provides fine perovskite-phase powders with ferroelectric properties which are particularly useful in a variety of electronic applications.

  3. Who's leading your process safety efforts

    SciTech Connect (OSTI)

    Bruce, S.R. (EQE International, San Francisco, CA (United States))

    1994-01-01

    To carry out a successful process safety management (PSM) program, management must complete three steps: Thoroughly understand the OSHA regulation and its benefits; Conduct a frank and complete review of current process conditions; and Communicate to all organizational levels the PSM goals. Management's leadership is the critical item to set up and maintain this safety-minded program. Instead of seeing PSM as a resource drain, operating companies should view if as a safety turnaround. This turnaround examines how and why operators continue to do business with hazardous chemicals. A better attitude toward safety repass tangible and intangible benefit such as improved profitability, employee morale and public image. A new or elaborate system isn't required, however, a new attitude is. Managers must be leaders to direct their organization toward their safety goals. This paper discusses how to implement a PSM program.

  4. LOFT lead rod test results evaluation. [PWR

    SciTech Connect (OSTI)

    Driskell, W.B.; Tolman, E.L.

    1980-07-30

    The purpose for evaluating the LOFT Lead Rod Test (simulations of large break, loss-of-coolant accidents) data was to determine; (a) if the centerline thermocouple and fuel rod elongation sensor data show indications of the collapsed fuel rod cladding, (b) the capability of the FRAP-T5 computer code to accurately predict cladding collapse, and (c) if cladding surface thermocouples enhance fuel rod cooling. With consideration to unresolved questions on data integrity, it was concluded that: the fuel rod centerline thermocouple and elongation sensor data do show indications of the fuel rod cladding collapse; the FRAP-T5 code conservatively predicts cladding collapse; and there is an indication that cladding surface thermocouples are enhancing fuel rod cooling.

  5. Lead paint abatement -- A technological review

    SciTech Connect (OSTI)

    Draper, A.C. III; Kapuscik, D.

    1994-12-31

    Abatement of lead from various surfaces proves to be a rapidly developing industry. Removal techniques and effectiveness varies greatly with varying substrates (wood, concrete, steel, etc.) and surface configurations including interior/exterior considerations, habitability and anticipated retrofit. Numerous technologies advances, and/or adaptations of long accepted removal techniques have recently emerged. Some of the more commonly used removal procedures including vacuum blasting, chemical stripping, scarifiers, grinders, sanders, etc. will be reviewed. Specific emphasis will be placed upon mode of application, positive and negative environmental aspects, and varying emissions generated. Personnel sampling data will be discussed with respect to associated personal protective equipment impact to derive the most cost productive environmentally conscious alternatives.

  6. Method for isolating nucleic acids

    DOE Patents [OSTI]

    Hurt, Jr., Richard Ashley; Elias, Dwayne A.

    2015-09-29

    The current disclosure provides methods and kits for isolating nucleic acid from an environmental sample. The current methods and compositions further provide methods for isolating nucleic acids by reducing adsorption of nucleic acids by charged ions and particles within an environmental sample. The methods of the current disclosure provide methods for isolating nucleic acids by releasing adsorbed nucleic acids from charged particles during the nucleic acid isolation process. The current disclosure facilitates the isolation of nucleic acids of sufficient quality and quantity to enable one of ordinary skill in the art to utilize or analyze the isolated nucleic acids for a wide variety of applications including, sequencing or species population analysis.

  7. Energy Efficiency Lead-by-Example Resources | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Lead-by-Example Resources Energy Efficiency Lead-by-Example Resources State and local governments can lead by example by promoting energy efficiency programs and policies for public facilities, equipment, and government operations. Find energy efficiency lead-by-example resources below. DOE Resource Federal Energy Management Program Publications. Other Resources Environmental Protection Agency: Lead by Example in Government Operations ACEEE's Lead By Example Initiatives National Governors

  8. Alternative Fuels Data Center: San Diego Leads in Promoting EVs

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    San Diego Leads in Promoting EVs to someone by E-mail Share Alternative Fuels Data Center: San Diego Leads in Promoting EVs on Facebook Tweet about Alternative Fuels Data Center: San Diego Leads in Promoting EVs on Twitter Bookmark Alternative Fuels Data Center: San Diego Leads in Promoting EVs on Google Bookmark Alternative Fuels Data Center: San Diego Leads in Promoting EVs on Delicious Rank Alternative Fuels Data Center: San Diego Leads in Promoting EVs on Digg Find More places to share

  9. Bush Administration Plays Leading Role in Studying and Addressing...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Bush Administration Plays Leading Role in Studying and Addressing Global Climate Change Bush Administration Plays Leading Role in Studying and Addressing Global Climate Change...

  10. Tritium Behavior in Lead Lithium Eutectic (LLE) at Low Tritium...

    Office of Environmental Management (EM)

    Behavior in Lead Lithium Eutectic (LLE) at Low Tritium Partial Pressure Tritium Behavior in Lead Lithium Eutectic (LLE) at Low Tritium Partial Pressure Presentation from the 33rd...

  11. University of Maryland Wins Architecture Prize, Pulls Into Lead...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of Maryland Wins Architecture Prize, Pulls Into Lead in 2011 Solar Decathlon University of Maryland Wins Architecture Prize, Pulls Into Lead in 2011 Solar Decathlon September 28,...

  12. Discovery of Weyl Semimetals May Lead to Novel Future Spintronic...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Discovery of Weyl Semimetals May Lead to Novel Future Spintronic Applications Discovery of Weyl Semimetals May Lead to Novel Future Spintronic Applications Print Wednesday, 09 ...

  13. SEEWEC Consortium lead partner Ghent University | Open Energy...

    Open Energy Info (EERE)

    SEEWEC Consortium lead partner Ghent University Jump to: navigation, search Name: SEEWEC Consortium lead partner Ghent University Address: Sint Pietersnieuwstraat 41 Place: Gent...

  14. Low Emission Asian Development (LEAD) Program | Open Energy Informatio...

    Open Energy Info (EERE)

    Low Emission Asian Development (LEAD) Program Redirect page Jump to: navigation, search REDIRECT Low Emissions Asian Development (LEAD) Program Retrieved from "http:...

  15. Bush Administration Plays Leading Role in Studying and Addressing...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Plays Leading Role in Studying and Addressing Global Climate Change Bush Administration Plays Leading Role in Studying and Addressing Global Climate Change February 27, 2007 - ...

  16. Questions about how plants die leads to climate change answers

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Questions about how plants die leads to climate change answers Questions about how plants die leads to climate change answers Understanding mechanisms of mortality will provide...

  17. Solar Decathlon 2015: Nation's Leading Sustainable Home Design...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Solar Decathlon 2015: Nation's Leading Sustainable Home Design Competition on the Horizon Solar Decathlon 2015: Nation's Leading Sustainable Home Design Competition on the Horizon...

  18. Report on the evaluation of the tritium producing burnable absorber rod lead test assembly. Revision 1

    SciTech Connect (OSTI)

    1997-03-01

    This report describes the design and fabrication requirements for a tritium-producing burnable absorber rod lead test assembly and evaluates the safety issues associated with tritium-producing burnable absorber rod irradiation on the operation of a commercial light water reactor. The report provides an evaluation of the tritium-producing burnable absorber rod design and concludes that irradiation can be performed within U.S. Nuclear Regulatory Commission regulations applicable to a commercial pressurized light water reactor.

  19. Src regulates the activity of SIRT2

    SciTech Connect (OSTI)

    Choi, You Hee; Kim, Hangun; Lee, Sung Ho; Jin, Yun-Hye; Lee, Kwang Youl

    2014-07-25

    Highlights: Src decreases the protein levels of Sirt2. Src inhibitor and knockdown of Src increase the protein levels of Sirt2. Src interacts with and phosphorylates Sirt2. Src regulate the activity of Sirt2. - Abstract: SIRT2 is a mammalian member of the Sirtuin family of NAD{sup +}-dependent protein deacetylases. The tyrosine kinase Src is involved in a variety of cellular signaling pathways, leading to the induction of DNA synthesis, cell proliferation, and cytoskeletal reorganization. The function of SIRT2 is modulated by post-translational modifications; however, the precise molecular signaling mechanism of SIRT2 through interactions with c-Src has not yet been established. In this study, we investigated the potential regulation of SIRT2 function by c-Src. We found that the protein levels of SIRT2 were decreased by c-Src, and subsequently rescued by the addition of a Src specific inhibitor, SU6656, or by siRNA-mediated knockdown of c-Src. The c-Src interacts with and phosphorylates SIRT2 at Tyr104. c-Src also showed the ability to regulate the deacetylation activity of SIRT2. Investigation on the phosphorylation of SIRT2 suggested that this was the method of c-Src-mediated SIRT2 regulation.

  20. Isotopic generator for bismuth-212 and lead-212 based on radium

    DOE Patents [OSTI]

    Hines, J.J.; Atcher, R.W.; Friedman, A.M.

    1985-01-30

    Disclosed are method and apparatus for providing radionuclides of bismuth-212 and lead-212. Thorium-228 and carrier solution starting material is input to a radiologically contained portion of an isotopic generator system, and radium-224 is separated from thorium-228 which is retained by a strongly basic anion exchange column. The separated radium-224 is transferred to an accessible, strongly acidic cationic exchange column. The cationic column retains the radium-224, and natural radioactive decay generates bismuth-212 and lead-212. The cationic exchange column can also be separated from the contained portion of the system and utilized without the extraordinary safety measures necessary in the contained portion. Furthermore, the cationic exchange column provides over a relatively long time period the short lived lead-212 and bismuth-212 radionuclides which are useful for a variety of medical therapies.

  1. Cell cycle nucleic acids, polypeptides and uses thereof

    DOE Patents [OSTI]

    Gordon-Kamm, William J. (Urbandale, IA); Lowe, Keith S. (Johnston, IA); Larkins, Brian A. (Tucson, AZ); Dilkes, Brian R. (Tucson, AZ); Sun, Yuejin (Westfield, IN)

    2007-08-14

    The invention provides isolated nucleic acids and their encoded proteins that are involved in cell cycle regulation. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. The present invention provides methods and compositions relating to altering cell cycle protein content, cell cycle progression, cell number and/or composition of plants.

  2. Method for construction of bacterial strains with increased succinic acid production

    DOE Patents [OSTI]

    Donnelly, Mark I. (Warrenville, IL); Sanville-Millard, Cynthia (Plainfield, IL); Chatterjee, Ranjini (Park Ridge, IL)

    2000-01-01

    A fermentation process for producing succinic acid is provided comprising selecting a bacterial strain that does not produce succinic acid in high yield, disrupting the normal regulation of sugar metabolism of said bacterial strain, and combining the mutant bacterial strain and selected sugar in anaerobic conditions to facilitate production of succinic acid. Also provided is a method for changing low yield succinic acid producing bacteria to high yield succinic acid producing bacteria comprising selecting a bacterial strain having a phosphotransferase system and altering the phosphotransferase system so as to allow the bacterial strain to simultaneously metabolize different sugars.

  3. Nucleic acids, compositions and uses thereof

    DOE Patents [OSTI]

    Preston, III, James F. (Micanopy, FL); Chow, Virginia (Gainesville, FL); Nong, Guang (Gainesville, FL); Rice, John D. (Gainesville, FL); St. John, Franz J. (Baltimore, MD)

    2012-02-21

    The subject invention provides at least one nucleic acid sequence encoding an aldouronate-utilization regulon isolated from Paenibacillus sp. strain JDR-2, a bacterium which efficiently utilizes xylan and metabolizes aldouronates (methylglucuronoxylosaccharides). The subject invention also provides a means for providing a coordinately regulated process in which xylan depolymerization and product assimilation are coupled in Paenibacillus sp. strain JDR-2 to provide a favorable system for the conversion of lignocellulosic biomass to biobased products. Additionally, the nucleic acid sequences encoding the aldouronate-utilization regulon can be used to transform other bacteria to form organisms capable of producing a desired product (e.g., ethanol, 1-butanol, acetoin, 2,3-butanediol, 1,3-propanediol, succinate, lactate, acetate, malate or alanine) from lignocellulosic biomass.

  4. Nucleic acid compositions and the encoding proteins

    DOE Patents [OSTI]

    Preston, III, James F.; Chow, Virginia; Nong, Guang; Rice, John D.; St. John, Franz J.

    2014-09-02

    The subject invention provides at least one nucleic acid sequence encoding an aldouronate-utilization regulon isolated from Paenibacillus sp. strain JDR-2, a bacterium which efficiently utilizes xylan and metabolizes aldouronates (methylglucuronoxylosaccharides). The subject invention also provides a means for providing a coordinately regulated process in which xylan depolymerization and product assimilation are coupled in Paenibacillus sp. strain JDR-2 to provide a favorable system for the conversion of lignocellulosic biomass to biobased products. Additionally, the nucleic acid sequences encoding the aldouronate-utilization regulon can be used to transform other bacteria to form organisms capable of producing a desired product (e.g., ethanol, 1-butanol, acetoin, 2,3-butanediol, 1,3-propanediol, succinate, lactate, acetate, malate or alanine) from lignocellulosic biomass.

  5. Ultrasound in lead-bismuth eutectic

    SciTech Connect (OSTI)

    Dierckx, M.; Van Dyck, D.

    2011-07-01

    The Belgian Nuclear Research Centre (SCK.CEN) is in the process of designing MYRRHA, a new multi-purpose irradiation facility to replace the ageing BR2. MYRRHA is a fast spectrum reactor cooled with lead-bismuth eutectic (LBE). As liquid metal is opaque to visual light, ultrasonic measurement techniques are selected to fulfill essential tasks that, according to our assessment, will be demanded by licensing authorities, in particular: fuel assembly identification and localization of a lost fuel assembly. To that end, a considerable research effort at SCK.CEN is devoted to study ultrasonic propagation in LBE. As ultrasonic experiments in LBE are elaborate and expensive to set up, we are particularly interested in to what extent experiments in water can be extrapolated to LBE - one of the main focuses of this article. We describe and present results of a first experiment with this goal which shows that the signal to noise ratio is better in LBE and that we even see small diffuse reflections up to 40 deg. off normal. On the other hand, we do not see internal reflections in stainless steel objects in LBE which we do in water. Therefore, we conclude that experiments in water can be used to validate algorithms for LBE on the condition that they do not rely on internal reflections. We also present solutions to tackle the essential tasks: fuel assembly identification and lost object localization. The requirements for the ultrasonic equipment implementing these solutions are also discussed. (authors)

  6. Optical high acidity sensor

    DOE Patents [OSTI]

    Jorgensen, Betty S. (Jemez Springs, NM); Nekimken, Howard L. (Los Alamos, NM); Carey, W. Patrick (Lynnwood, WA); O'Rourke, Patrick E. (Martinez, GA)

    1997-01-01

    An apparatus and method for determining acid concentrations in solutions having acid concentrations of from about 0.1 Molar to about 16 Molar is disclosed. The apparatus includes a chamber for interrogation of the sample solution, a fiber optic light source for passing light transversely through the chamber, a fiber optic collector for receiving the collimated light after transmission through the chamber, a coating of an acid resistant polymeric composition upon at least one fiber end or lens, the polymeric composition in contact with the sample solution within the chamber and having a detectable response to acid concentrations within the range of from about 0.1 Molar to about 16 Molar, a measurer for the response of the polymeric composition in contact with the sample solution, and, a comparer of the measured response to predetermined standards whereby the acid molarity of the sample solution within the chamber can be determined. Preferably, a first lens is attached to the end of the fiber optic light source, the first lens adapted to collimate light from the fiber optic light source, and a second lens is attached to the end of the fiber optic collector for focusing the collimated light after transmission through the chamber.

  7. Optical high acidity sensor

    DOE Patents [OSTI]

    Jorgensen, B.S.; Nekimken, H.L.; Carey, W.P.; O`Rourke, P.E.

    1997-07-22

    An apparatus and method for determining acid concentrations in solutions having acid concentrations of from about 0.1 Molar to about 16 Molar is disclosed. The apparatus includes a chamber for interrogation of the sample solution, a fiber optic light source for passing light transversely through the chamber, a fiber optic collector for receiving the collimated light after transmission through the chamber, a coating of an acid resistant polymeric composition upon at least one fiber end or lens, the polymeric composition in contact with the sample solution within the chamber and having a detectable response to acid concentrations within the range of from about 0.1 Molar to about 16 Molar, a measurer for the response of the polymeric composition in contact with the sample solution, and a comparer of the measured response to predetermined standards whereby the acid molarity of the sample solution within the chamber can be determined. Preferably, a first lens is attached to the end of the fiber optic light source, the first lens adapted to collimate light from the fiber optic light source, and a second lens is attached to the end of the fiber optic collector for focusing the collimated light after transmission through the chamber. 10 figs.

  8. Get the lead out! removing lead-based paint on hydro plant structures

    SciTech Connect (OSTI)

    Johnson, M.L.

    1996-05-01

    This article describes a hydroblasting technology used to remove lead-based surface coatings from the steel associated with the flood gates at the Wirtz Dam. Using this technology and an advanced moisture-cured urethane coating, the Lower Colorado River Authority was able to save more than $250,000 in materials, labor, and waste disposal costs.

  9. Microsoft Word - Final Lead Assembly SA.doc

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... of European Fabrication of Lead MOX Assemblies. ...... 20 Table 4. Comparison of Human Health ...

  10. Building Standards Lead-by-Example Resources | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Standards Lead-by-Example Resources Building Standards Lead-by-Example Resources State and local governments can lead by example by promoting energy efficiency programs and policies for public facilities, equipment, and government operations. Find building standards lead-by-example resources below. DOE Resource National Best Practices Manual For Building High Performance Schools. Other Resource Roadmap to Green Government Buildings

  11. Interrelationship of Program Regulations and Financial Assistance Regulations

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1980-04-24

    The purpose of this Order is to set forth the interrelationship between all program regulations which will result in assistance awards (Program Regulations) and the Department of Energy Assistance Regulations (DOE-AR, 10 CRF Part 600), including procedures for exceptions, deviations or waivers.

  12. Distributed Generation Lead-by-Example Resources | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Lead-by-Example Resources Distributed Generation Lead-by-Example Resources State governments can lead by example by promoting renewable energy programs and policies. Efforts to lead by example include using renewable energy resources (including alternative fuel for vehicles) and incorporating renewable energy generation into new and existing public buildings. Find the lead by example resources below. DOE Resources Clean Energy Strategies for Local Governments: On-Site Renewable Energy Generation

  13. Alternative Fuels Data Center: Alabama City Leads With Biodiesel and

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    Ethanol Alabama City Leads With Biodiesel and Ethanol to someone by E-mail Share Alternative Fuels Data Center: Alabama City Leads With Biodiesel and Ethanol on Facebook Tweet about Alternative Fuels Data Center: Alabama City Leads With Biodiesel and Ethanol on Twitter Bookmark Alternative Fuels Data Center: Alabama City Leads With Biodiesel and Ethanol on Google Bookmark Alternative Fuels Data Center: Alabama City Leads With Biodiesel and Ethanol on Delicious Rank Alternative Fuels Data

  14. Self-regulating valve

    DOE Patents [OSTI]

    Humphreys, D.A.

    1982-07-20

    A variable, self-regulating valve having a hydraulic loss coefficient proportional to a positive exponential power of the flow rate. The device includes two objects in a flow channel and structure which assures that the distance between the two objects is an increasing function of the flow rate. The range of spacing between the objects is such that the hydraulic resistance of the valve is an increasing function of the distance between the two objects so that the desired hydraulic loss coefficient as a function of flow rate is obtained without variation in the flow area.

  15. Regulators, Boards, Councils - Hanford Site

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Regulators, Boards, Councils Hanford Advisory Board Hanford Natural Resource Trustee Council Environmental Protection Agency Washington State Department of Ecology Defense...

  16. Temperature controlled high voltage regulator

    DOE Patents [OSTI]

    Chiaro, Jr., Peter J. (Clinton, TN); Schulze, Gerald K. (Knoxville, TN)

    2004-04-20

    A temperature controlled high voltage regulator for automatically adjusting the high voltage applied to a radiation detector is described. The regulator is a solid state device that is independent of the attached radiation detector, enabling the regulator to be used by various models of radiation detectors, such as gas flow proportional radiation detectors.

  17. Plant fatty acid hydroxylase

    DOE Patents [OSTI]

    Somerville, Chris (Portola Valley, CA); van de Loo, Frank (Lexington, KY)

    2000-01-01

    The present invention relates to the identification of nucleic acid sequences and constructs, and methods related thereto, and the use of these sequences and constructs to produce genetically modified plants for the purpose of altering the composition of plant oils, waxes and related compounds.

  18. Synthesis of acid addition salt of delta-aminolevulinic acid from 5-bromo levulinic acid esters

    DOE Patents [OSTI]

    Moens, Luc (Lakewood, CO)

    2003-06-24

    A process of preparing an acid addition salt of delta-aminolevulinc acid comprising: a) dissolving a lower alkyl 5-bromolevulinate and hexamethylenetetramine in a solvent selected from the group consisting of water, ethyl acetate, chloroform, acetone, ethanol, tetrahydrofuran and acetonitrile, to form a quaternary ammonium salt of the lower alkyl 5-bromolevulinate; and b) hydrolyzing the quaternary ammonium salt with an inorganic acid to form an acid addition salt of delta-aminolevulinic acid.

  19. EFFECTS OF NITRIC ACID ON CRITICALITY SAFETY ANALYSIS

    SciTech Connect (OSTI)

    Williamson, B.

    2011-08-18

    As nitric acid molarity is increased, there are two competing phenomena affecting the reactivity of the system. First, there is interaction between each of the 10 wells in the basket-like insert. As the molarity of the nitric acid solution is increased (it moves from 100% water to 100% HNO{sub 3}), the hydrogen atom density decreases by about 80%. However, it remains a relatively efficient moderator. The moderating ratio of nitric acid is about 90% that of water. As the media between the wells is changed from 100% water to 100% nitric acid, the density of the media increases by 50%. A higher density typically leads to a better reflector. However, when the macroscopic scattering cross sections are considered, nitric acid is a much worse reflector than water. The effectiveness of nitric acid as a reflector is about 40% that of water. Since the media between the wells become a worse reflector and still remains an effective moderator, interaction between the wells increases. This phenomenon will cause reactivity to increase as nitric acid molarity increases. The seond phenomenon is due to the moderating ratio changing in the high concentration fissile-nitric acid solution in the 10 wells. Since the wells contain relatively small volumes of high concentration solutions, a small decrease in moderating power has a large effect on reactivity. This is due to the fact that neutrons are more likely to escape the high concentration fissile solution before causing another fission event. The result of this phenomenon is that as nitric acid molarity increases, reactivity decreases. Recent studies have shown that the second phenomenon is indeed the dominating force in determining reactivity changes in relation to nitric acid molarity changes. When considering the system as a whole, as nitric acid molarity increases, reactivity decreases.

  20. Fatty acid-producing hosts

    DOE Patents [OSTI]

    Pfleger, Brian F; Lennen, Rebecca M

    2013-12-31

    Described are hosts for overproducing a fatty acid product such as a fatty acid. The hosts include an exogenous nucleic acid encoding a thioesterase and, optionally, an exogenous nucleic acid encoding an acetyl-CoA carboxylase, wherein an acyl-CoA synthetase in the hosts are functionally delected. The hosts prefereably include the nucleic acid encoding the thioesterase at an intermediate copy number. The hosts are preferably recominantly stable and growth-competent at 37.degree. C. Methods of producing a fatty acid product comprising culturing such hosts at 37.degree. C. are also described.

  1. Lab Discovery: Water Leads to Chemical that "Gunks Up" Biofuels...

    Energy Savers [EERE]

    Lab Discovery: Water Leads to Chemical that "Gunks Up" Biofuels Production Lab Discovery: Water Leads to Chemical that "Gunks Up" Biofuels Production November 20, 2014 - 12:16pm ...

  2. DOE ZERH Second Leading Builder Round Table Meeting Report

    Broader source: Energy.gov [DOE]

    On October 23rd-24th, 2014, the ZERH program held its Second Leading Production Builder Round Table Meeting in Suwanee, GA. The purpose was to provide top executives from leading builders with a...

  3. Spotlight on Rutland County, Vermont: How Local Ties Lead to...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Rutland County, Vermont: How Local Ties Lead to Local Wins Spotlight on Rutland County, Vermont: How Local Ties Lead to Local Wins Spotlight on Rutland County, Vermont: How Local...

  4. GE leads the way in photonics research | GE Global Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GE continues leading role in photonics industry - from LED to digital x-ray Click to email ... GE continues leading role in photonics industry - from LED to digital x-ray Danielle ...

  5. Fatal pediatric poisoning from leaded paint--Wisconsin, 1990

    SciTech Connect (OSTI)

    Not Available

    1991-03-29

    Although fatal lead poisoning among children occurs rarely in the United States, it represents a medical and public health emergency. This report summarizes the investigation of a child who died from poisoning associated with ingestion of lead-based paint.

  6. Getting the lead out: Citizen involvement in the Williamsburg Bridge lead paint removal project

    SciTech Connect (OSTI)

    Forker, T.R.

    1997-08-01

    This paper examines the process and results of citizen involvement in developing new environmental control and compliance procedures used by the New York City Department of Transportation (NYC DOT) for lead paint removal on the Williamsburg Bridge and other structures. As a case study of the effects of public involvement in environmental decision-making, the study identifies and discusses the factors that produced failures or successes in satisfying the citizen`s concerns about health risks and the effectiveness of the selected pollution control technology.

  7. Procurement Standards Lead-by-Example Resources | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Procurement Standards Lead-by-Example Resources Procurement Standards Lead-by-Example Resources State and local governments can lead by example by promoting energy efficiency programs and policies for public facilities, equipment, and government operations. Find procurement standards lead-by-example resources below. DOE Resource Energy-Efficient Product Procurement. Other Resources ENERGY STAR®: All Certified Products New York State Energy Research and Development Authority: Procurement

  8. Protocol, Qualification Standard for the Site Lead Program - May 2011 |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Qualification Standard for the Site Lead Program - May 2011 Protocol, Qualification Standard for the Site Lead Program - May 2011 May 2011 Qualification Standard for the Site Lead Program This Qualification Standard establishes common functional area competency requirements for personnel assigned as Site Leads in the Office of Safety and Emergency Management Evaluations. Satisfactory and documented completion of the competency requirements contained in this Standard

  9. Retrofit Program Lead-by-Example Resources | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Retrofit Program Lead-by-Example Resources Retrofit Program Lead-by-Example Resources State and local governments can lead by example by promoting energy efficiency programs and policies for public facilities, equipment, and government operations. Find retrofit program lead-by-example resources below. Local Government Climate and Energy Strategy Series: Energy Efficiency in Local Government Operations: A Guide to Developing and Implementing Greenhouse Gas Reduction Programs ACEEE: Comprehensive

  10. Cities Leading Through Energy Analysis and Planning Infographic |

    Office of Environmental Management (EM)

    Department of Energy Cities Leading Through Energy Analysis and Planning Infographic Cities Leading Through Energy Analysis and Planning Infographic The Cities Leading through Energy Analysis and Planning (Cities-LEAP) project delivers standardized, localized energy data and analysis that enables cities to lead clean energy innovation and integrate strategic energy analysis into decision making. Two Cities-LEAP infographics catalog the programs and tools currently supporting local

  11. 2015 Leading Builder Round Table Report | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Leading Builder Round Table Report 2015 Leading Builder Round Table Report The nation is on the cusp of a dramatic movement to zero energy ready homes. This includes statewide codes, large developments, and a growing amount of commitment to the DOE Zero Energy Ready Home program. Much of this progress can be attributed to a small contingent of our nation's leading builders who are demonstrating the technical, cost, and design feasibility for this level of excellence At the 2015 Leading Builder

  12. Alternative Fuels Data Center: Smoky Mountains Leads the Way in

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    Implementing Alternative Fuels Smoky Mountains Leads the Way in Implementing Alternative Fuels to someone by E-mail Share Alternative Fuels Data Center: Smoky Mountains Leads the Way in Implementing Alternative Fuels on Facebook Tweet about Alternative Fuels Data Center: Smoky Mountains Leads the Way in Implementing Alternative Fuels on Twitter Bookmark Alternative Fuels Data Center: Smoky Mountains Leads the Way in Implementing Alternative Fuels on Google Bookmark Alternative Fuels Data

  13. Vermont Hazardous Waste Management Regulations | Open Energy...

    Open Energy Info (EERE)

    Hazardous Waste Management Regulations Jump to: navigation, search OpenEI Reference LibraryAdd to library Legal Document- RegulationRegulation: Vermont Hazardous Waste Management...

  14. Lubrication with boric acid additives

    DOE Patents [OSTI]

    Erdemir, Ali (Naperville, IL)

    2000-01-01

    Self-lubricating resin compositions including a boric acid additive and a synthetic polymer including those thermoset materials.

  15. Carboxylic acid sorption regeneration process

    DOE Patents [OSTI]

    King, C. Judson (Kensington, CA); Poole, Loree J. (Baton Rouge, LA)

    1995-01-01

    Carboxylic acids are sorbed from aqueous feedstocks into an organic liquid phase or onto a solid adsorbent. The acids are freed from the sorbent phase by treating it with aqueous alkylamine thus forming an alkylammonium carboxylate which is dewatered and decomposed to the desired carboxylic acid and the alkylamine.

  16. Pantothenic acid biosynthesis in zymomonas

    DOE Patents [OSTI]

    Tao, Luan; Tomb, Jean-Francois; Viitanen, Paul V.

    2014-07-01

    Zymomonas is unable to synthesize pantothenic acid and requires this essential vitamin in growth medium. Zymomonas strains transformed with an operon for expression of 2-dehydropantoate reductase and aspartate 1-decarboxylase were able to grow in medium lacking pantothenic acid. These strains may be used for ethanol production without pantothenic acid supplementation in seed culture and fermentation media.

  17. Carboxylic acid sorption regeneration process

    DOE Patents [OSTI]

    King, C.J.; Poole, L.J.

    1995-05-02

    Carboxylic acids are sorbed from aqueous feedstocks into an organic liquid phase or onto a solid adsorbent. The acids are freed from the sorbent phase by treating it with aqueous alkylamine thus forming an alkylammonium carboxylate which is dewatered and decomposed to the desired carboxylic acid and the alkylamine. 10 figs.

  18. Lead contamination in the Mallard (Anas platyrhynchos) in Italy

    SciTech Connect (OSTI)

    Tirelli, E.; Maestrini, N.; Govoni, S.; Catelli, E.

    1996-05-01

    The main cause of lead poisoning in waterfowl is due to ingestion of spent lead shot in areas of high hunting pressure . Italian literature on this subject is very scarce and the few available studies concern episodic cases. to contribute to the assessment of the impact of lead shot in waterfowl in Italy, systematic research has been carried out on shorebirds caught for ringing in Tiscany and are continuing on dabbling and diving ducks by checking the presence of lead in blood samples and lead shot in the gizzard. This study targets the mallard duck. 17 refs., 1 fig., 1 tab.

  19. Lab Breakthrough: Lead-free Solder | Department of Energy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Lead-free Solder Lab Breakthrough: Lead-free Solder May 24, 2012 - 10:45am Addthis Iver Anderson, senior metallurgist at Ames Laboratory, explains the importance of lead-free solder in taking hazardous lead out of the environment by eliminating it from discarded computers and electronics that wind up in landfills. Anderson led a team that developed a tin-silver-copper replacement for traditional lead-tin solder that has been adopted by more than 50 companies worldwide. View the entire Lab

  20. Unique Auxin Regulation Mechanism Discovered

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Unique Auxin Regulation Mechanism Discovered Unique Auxin Regulation Mechanism Discovered Print Wednesday, 29 August 2007 00:00 The plant hormone auxin regulates many plant growth and development processes, including shoot growth, root branching, fruit ripening, tropisms, and flowering. But how such a simple molecule elicits such a variety of cellular responses has been a mystery. An important breakthrough came in 2005, wh en a conserved plant protein known as TIR1 (part of a protein destruction

  1. Composition for nucleic acid sequencing

    DOE Patents [OSTI]

    Korlach, Jonas (Ithaca, NY); Webb, Watt W. (Ithaca, NY); Levene, Michael (Ithaca, NY); Turner, Stephen (Ithaca, NY); Craighead, Harold G. (Ithaca, NY); Foquet, Mathieu (Ithaca, NY)

    2008-08-26

    The present invention is directed to a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the polymerization reaction is measured on a molecule of nucleic acid, i.e. the activity of a nucleic acid polymerizing enzyme on the template nucleic acid molecule to be sequenced is followed in real time. The sequence is deduced by identifying which base is being incorporated into the growing complementary strand of the target nucleic acid by the catalytic activity of the nucleic acid polymerizing enzyme at each step in the sequence of base additions. A polymerase on the target nucleic acid molecule complex is provided in a position suitable to move along the target nucleic acid molecule and extend the oligonucleotide primer at an active site. A plurality of labelled types of nucleotide analogs are provided proximate to the active site, with each distinguishable type of nucleotide analog being complementary to a different nucleotide in the target nucleic acid sequence. The growing nucleic acid strand is extended by using the polymerase to add a nucleotide analog to the nucleic acid strand at the active site, where the nucleotide analog being added is complementary to the nucleotide of the target nucleic acid at the active site. The nucleotide analog added to the oligonucleotide primer as a result of the polymerizing step is identified. The steps of providing labelled nucleotide analogs, polymerizing the growing nucleic acid strand, and identifying the added nucleotide analog are repeated so that the nucleic acid strand is further extended and the sequence of the target nucleic acid is determined.

  2. Invasive cleavage of nucleic acids

    DOE Patents [OSTI]

    Prudent, James R. (Madison, WI); Hall, Jeff G. (Madison, WI); Lyamichev, Victor I. (Madison, WI); Brow, Mary Ann D. (Madison, WI); Dahlberg, James E. (Madison, WI)

    1999-01-01

    The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.

  3. Invasive cleavage of nucleic acids

    DOE Patents [OSTI]

    Prudent, James R. (Madison, WI); Hall, Jeff G. (Madison, WI); Lyamichev, Victor I. (Madison, WI); Brow, Mary Ann D. (Madison, WI); Dahlberg, James E. (Madison, WI)

    2002-01-01

    The present invention relates to means for the detection and characterization of nucleic acid sequences, as well as variations in nucleic acid sequences. The present invention also relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. The structure-specific nuclease activity of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.

  4. certification, compliance and enforcement regulations for Commercial...

    Office of Environmental Management (EM)

    regulations for Commercial Refrigeration Equipment (CRE) certification, compliance and enforcement regulations for Commercial Refrigeration Equipment (CRE) The current ...

  5. Synthesis of amino acids

    DOE Patents [OSTI]

    Davis, J.W. Jr.

    1979-09-21

    A method is described for synthesizing amino acids preceding through novel intermediates of the formulas: R/sub 1/R/sub 2/C(OSOC1)CN, R/sub 1/R/sub 2/C(C1)CN and (R/sub 1/R/sub 2/C(CN)O)/sub 2/SO wherein R/sub 1/ and R/sub 2/ are each selected from hydrogen and monovalent hydrocarbon radicals of 1 to 10 carbon atoms. The use of these intermediates allows the synthesis steps to be exothermic and results in an overall synthesis method which is faster than the synthesis methods of the prior art.

  6. Litigation, Regulation and Enforcement | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Litigation, Regulation and Enforcement Litigation, Regulation and Enforcement Litigation, Regulation and Enforcement Offices of the Deputy General Counsel for Litigation, Regulation and Enforcement Office of the Assistant General Counsel for Litigation (GC-31) Office of the Assistant General Counsel for Enforcement (GC-32) Office of the Assistant General Counsel for Legislation, Regulation and Energy Efficiency (GC-33) Litigation, Regulation and Enforcement Litigation Enforcement Legislation,

  7. Nucleic Acid Detection Methods

    DOE Patents [OSTI]

    Smith, Cassandra L. (Boston, MA); Yaar, Ron (Brookline, MA); Szafranski, Przemyslaw (Boston, MA); Cantor, Charles R. (Boston, MA)

    1998-05-19

    The invention relates to methods for rapidly determining the sequence and/or length a target sequence. The target sequence may be a series of known or unknown repeat sequences which are hybridized to an array of probes. The hybridized array is digested with a single-strand nuclease and free 3'-hydroxyl groups extended with a nucleic acid polymerase. Nuclease cleaved heteroduplexes can be easily distinguish from nuclease uncleaved heteroduplexes by differential labeling. Probes and target can be differentially labeled with detectable labels. Matched target can be detected by cleaving resulting loops from the hybridized target and creating free 3-hydroxyl groups. These groups are recognized and extended by polymerases added into the reaction system which also adds or releases one label into solution. Analysis of the resulting products using either solid phase or solution. These methods can be used to detect characteristic nucleic acid sequences, to determine target sequence and to screen for genetic defects and disorders. Assays can be conducted on solid surfaces allowing for multiple reactions to be conducted in parallel and, if desired, automated.

  8. Nucleic acid detection methods

    DOE Patents [OSTI]

    Smith, C.L.; Yaar, R.; Szafranski, P.; Cantor, C.R.

    1998-05-19

    The invention relates to methods for rapidly determining the sequence and/or length a target sequence. The target sequence may be a series of known or unknown repeat sequences which are hybridized to an array of probes. The hybridized array is digested with a single-strand nuclease and free 3{prime}-hydroxyl groups extended with a nucleic acid polymerase. Nuclease cleaved heteroduplexes can be easily distinguish from nuclease uncleaved heteroduplexes by differential labeling. Probes and target can be differentially labeled with detectable labels. Matched target can be detected by cleaving resulting loops from the hybridized target and creating free 3-hydroxyl groups. These groups are recognized and extended by polymerases added into the reaction system which also adds or releases one label into solution. Analysis of the resulting products using either solid phase or solution. These methods can be used to detect characteristic nucleic acid sequences, to determine target sequence and to screen for genetic defects and disorders. Assays can be conducted on solid surfaces allowing for multiple reactions to be conducted in parallel and, if desired, automated. 18 figs.

  9. Secretary Bodman to Lead Presidential Delegation to Baku, Azerbaijan for

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    2008 Energy Summit | Department of Energy to Lead Presidential Delegation to Baku, Azerbaijan for 2008 Energy Summit Secretary Bodman to Lead Presidential Delegation to Baku, Azerbaijan for 2008 Energy Summit November 11, 2008 - 4:47pm Addthis WASHINGTON, DC - U.S. Secretary of Energy Samuel W. Bodman will lead a Presidential Delegation to Azerbaijan this week to participate in the 2008 Energy Summit hosted by Azerbaijani President Ilham Aliyev on November 14. During the trip, Secretary

  10. Energy Secretary Bodman Leads US Delegation to International Energy Agency

    Energy Savers [EERE]

    Ministerial | Department of Energy Leads US Delegation to International Energy Agency Ministerial Energy Secretary Bodman Leads US Delegation to International Energy Agency Ministerial May 2, 2005 - 12:41pm Addthis PARIS, FRANCE -- Secretary of Energy Samuel W. Bodman this week is leading the U.S. Delegation to the Ministerial Meeting of the International Energy Agency (IEA), being held in Paris. Secretary Bodman will emphasize three principles at the IEA Ministerial -- that energy security

  11. OCRWM Selects Sandia as Lead Laboratory | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    OCRWM Selects Sandia as Lead Laboratory OCRWM Selects Sandia as Lead Laboratory January 18, 2006 - 10:45am Addthis Also reserves building at Idaho National Laboratory as future training facility WASHINGTON, DC - The Department of Energy's Office of Civilian Radioactive Waste Management (OCRWM) has announced it will designate Sandia National Laboratories as its lead laboratory to integrate repository science work for the Yucca Mountain Project. That work, which is currently overseen by OCRWM's

  12. U.S. Leads International Collaborative to Address Wind Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Development/Wildlife Challenges | Department of Energy Leads International Collaborative to Address Wind Energy Development/Wildlife Challenges U.S. Leads International Collaborative to Address Wind Energy Development/Wildlife Challenges May 18, 2015 - 5:46pm Addthis The U.S. Department of Energy (DOE) is leading a new International Energy Agency (IEA) Wind Task to address concerns about the environmental effects of wind energy technology. Task 34, also known as WREN (Working together to

  13. Kjiersten Fagnan Appointed NERSC/JGI Engagement Lead

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Kjiersten Fagnan Named NERSC/JGI Engagement Lead Kjiersten Fagnan Appointed NERSC/JGI Engagement Lead September 1, 2014 fagnan.jpg Kjiersten Fagnan has been named the NERSC/JGI Engagement Lead for Joint Genome Institute (JGI) computational and data analysis efforts carried out at the Department of Energy's (DOE) National Energy Research Scientific Computing Center (NERSC). Fagnan, who holds a Ph.D. in Applied Mathematics from the University of Washington, started at NERSC as a petascale postdoc

  14. Solar wind conditions leading to efficient radiation belt electron

    Office of Scientific and Technical Information (OSTI)

    acceleration: A superposed epoch analysis (Journal Article) | SciTech Connect Solar wind conditions leading to efficient radiation belt electron acceleration: A superposed epoch analysis Citation Details In-Document Search This content will become publicly available on September 7, 2016 Title: Solar wind conditions leading to efficient radiation belt electron acceleration: A superposed epoch analysis In this study by determining preferential solar wind conditions leading to efficient

  15. Bush Administration Plays Leading Role in Studying and Addressing Global

    Energy Savers [EERE]

    Climate Change | Department of Energy Plays Leading Role in Studying and Addressing Global Climate Change Bush Administration Plays Leading Role in Studying and Addressing Global Climate Change February 27, 2007 - 3:49pm Addthis Washington, DC - Continuing to take the lead in addressing global climate change, Energy Secretary Samuel Bodman, Environmental Protection Agency (EPA) Administrator Stephen Johnson, and National Oceanic and Atmospheric Administration (NOAA) Administrator Vice

  16. Energy Department to Lead Workshop on Tribal Renewable Energy Development

    Office of Environmental Management (EM)

    in Oklahoma | Department of Energy Lead Workshop on Tribal Renewable Energy Development in Oklahoma Energy Department to Lead Workshop on Tribal Renewable Energy Development in Oklahoma June 1, 2015 - 9:50am Addthis Proposing and leading energy projects is a complex process. Each project and local energy situation is unique. Oklahoma tribal energy leaders have an opportunity to explore the tribal energy project development and financing process hands-on at an interactive workshop being

  17. EM Leads Successful Workshop Supporting Fukushima Cleanup | Department of

    Office of Environmental Management (EM)

    Energy Leads Successful Workshop Supporting Fukushima Cleanup EM Leads Successful Workshop Supporting Fukushima Cleanup August 8, 2013 - 12:00pm Addthis TOKYO - An EM-led U.S. delegation conducted its third workshop last month to provide expertise to Japanese officials leading the cleanup of the Fukushima Daiichi Nuclear Power Plant site and surrounding area, this time addressing priorities identified by Japan's government agencies. At the request of the Japanese Ministry of Environment

  18. Sec. Herrington Leads Delegation in Response to Chernobyl Accident...

    National Nuclear Security Administration (NNSA)

    Photo Gallery Jobs Apply for Our Jobs Our Jobs Working at NNSA Blog Home About Us Our History NNSA Timeline Sec. Herrington Leads Delegation in Response to ... Sec....

  19. Novel Nanoparticle Production Method Could Lead to Better Lights...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Novel Nanoparticle Production Method Could Lead to Better Lights, Lenses, Solar Cells - Sandia Energy Energy Search Icon Sandia Home Locations Contact Us Employee Locator Energy & ...

  20. Westinghouse Selects Bill Keeley To Lead Strategic Planning and...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    TRU Solutions LLC (WTS) has appointed Bill Keeley to lead the integrated functions of Strategic Planning and Communication at the Waste Isolation Pilot Plant (WIPP). WTS is the...

  1. DOE ZERH Second Leading Builder Round Table Meeting Report |...

    Broader source: Energy.gov (indexed) [DOE]

    GA. The purpose was to provide top executives from leading builders with a forum to share business and technical lessons learned, identify a list of common challenges delivering...

  2. West Africa Emerges as Leading Region in Africa for Renewable...

    Open Energy Info (EERE)

    West Africa Emerges as Leading Region in Africa for Renewable Energy and Energy Efficiency Home > Groups > Clean and Renewable Energy Dc's picture Submitted by Dc(266) Contributor...

  3. DOE/NNSA's Nonproliferation Experts Lead First Workshop on the...

    National Nuclear Security Administration (NNSA)

    Apply for Our Jobs Our Jobs Working at NNSA Blog Home Library Press Releases DOENNSA's Nonproliferation Experts Lead First Workshop on ... DOENNSA's Nonproliferation ...

  4. Weerts to lead Physical Sciences and Engineering directorate...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Weerts to lead Physical Sciences and Engineering directorate By Lynn Tefft Hoff * August 10, 2015 Tweet EmailPrint Hendrik (Harry) Joseph Weerts has been named the associate...

  5. Operations and Maintenance Lead-by-Example Resources

    Broader source: Energy.gov [DOE]

    State and local governments can lead by example by promoting energy efficiency programs and policies for public facilities, equipment, and government operations.

  6. Solar wind conditions leading to efficient radiation belt electron...

    Office of Scientific and Technical Information (OSTI)

    Solar wind conditions leading to efficient radiation belt electron acceleration: A superposed epoch analysis Citation Details In-Document Search This content will become publicly ...

  7. Solar Decathlon Team Leading the Way Toward Sustainable Living...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Team Leading the Way Toward Sustainable Living, Even in the Wake of Disasters Solar ... | Courtesy of the University of Illinois at Urbana-Champaign Solar Decathlon Team. ...

  8. Vapor cooled current lead for cryogenic electrical equipment

    DOE Patents [OSTI]

    Vansant, James H. (Tracy, CA)

    1983-01-01

    Apparatus and method are provided for conducting electric current to cryogenic electrical equipment devices. A combination of inner and outer tubes together form a plurality of hollow composite tubes housed in a sheath. Top and bottom block mounting means are fitted to hold the composite tubes and are affixed to the ends of the sheath. This combination forms a current lead. The current lead is attached to a cryogenic device housing a fluid coolant which moves through the current lead, cooling the current lead as the fluid travels.

  9. Mainzer taps Gendron, Ehli to lead Power and Corporate Strategy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Mainzer-taps-Gendron-Ehli-to-lead-Power-and-Corporate-Strategy Sign In About | Careers | Contact | Investors | bpa.gov Search News & Us Expand News & Us Projects & Initiatives...

  10. Indonesia-Low Emissions Asian Development (LEAD) Program | Open...

    Open Energy Info (EERE)

    the growth of greenhouse gas emissions. The LEAD program supports and enhances country-led development programs, plans, and policies, and complements efforts of other...

  11. Thailand-Low Emissions Asian Development (LEAD) Program | Open...

    Open Energy Info (EERE)

    the growth of greenhouse gas emissions. The LEAD program supports and enhances country-led development programs, plans, and policies, and complements efforts of other...

  12. Philippines-Low Emissions Asian Development (LEAD) Program |...

    Open Energy Info (EERE)

    the growth of greenhouse gas emissions. The LEAD program supports and enhances country-led development programs, plans, and policies, and complements efforts of other...

  13. Papua New Guinea-Low Emissions Asian Development (LEAD) Program...

    Open Energy Info (EERE)

    the growth of greenhouse gas emissions. The LEAD program supports and enhances country-led development programs, plans, and policies, and complements efforts of other...

  14. India-Low Emissions Asian Development (LEAD) Program | Open Energy...

    Open Energy Info (EERE)

    the growth of greenhouse gas emissions. The LEAD program supports and enhances country-led development programs, plans, and policies, and complements efforts of other...

  15. Cambodia-Low Emissions Asian Development (LEAD) Program | Open...

    Open Energy Info (EERE)

    the growth of greenhouse gas emissions. The LEAD program supports and enhances country-led development programs, plans, and policies, and complements efforts of other...

  16. Bangladesh-Low Emissions Asian Development (LEAD) Program | Open...

    Open Energy Info (EERE)

    the growth of greenhouse gas emissions. The LEAD program supports and enhances country-led development programs, plans, and policies, and complements efforts of other...

  17. Vietnam-Low Emissions Asian Development (LEAD) Program | Open...

    Open Energy Info (EERE)

    the growth of greenhouse gas emissions. The LEAD program supports and enhances country-led development programs, plans, and policies, and complements efforts of other...

  18. Malaysia-Low Emissions Asian Development (LEAD) Program | Open...

    Open Energy Info (EERE)

    the growth of greenhouse gas emissions. The LEAD program supports and enhances country-led development programs, plans, and policies, and complements efforts of other...

  19. Nepal-Low Emissions Asian Development (LEAD) Program | Open Energy...

    Open Energy Info (EERE)

    the growth of greenhouse gas emissions. The LEAD program supports and enhances country-led development programs, plans, and policies, and complements efforts of other...

  20. Laos-Low Emissions Asian Development (LEAD) Program | Open Energy...

    Open Energy Info (EERE)

    the growth of greenhouse gas emissions. The LEAD program supports and enhances country-led development programs, plans, and policies, and complements efforts of other...

  1. Sandia Energy - New Liquid Salt Electrolytes Could Lead to Cost...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Salt Electrolytes Could Lead to Cost-Effective Flow Batteries Chemical technologist Harry Pratt synthesizes a copper-based ionic liquid. (Photo by Randy Montoya) Sandia...

  2. Sound Project Management, Safe and Efficient Work Lead to Savings...

    Office of Environmental Management (EM)

    Sound Project Management, Safe and Efficient Work Lead to Savings for More Recovery Act Cleanup Sound management practices and safe, efficient work have led to cost savings and ...

  3. Y-12 leads the way in specialized machining

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    leads the way in specialized machining The original nine major buildings at Y-12, five "Alpha" buildings and four "Beta" buildings were originally built to house calutrons to...

  4. Ames Laboratory to lead new consortium to advance refrigeration...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Laboratory to lead new consortium to advance refrigeration technology Ames Laboratory will ... friendly and energy-efficient refrigeration technologies, sponsored by DOE's ...

  5. Ames Laboratory to Lead New Research Effort to Address Shortages...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Laboratory to Lead New Research Effort to Address Shortages in Rare Earth and Other Critical Materials Ames Laboratory ... electric vehicles, advanced batteries and a host of ...

  6. Lead-free Thin Film Piezoelectric Devices - Energy Innovation...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    1% only, and thus do not efficiently generate mechanical or electrical energy. Benefits* Made of a lead-free and abundant substance * Higher efficiency than conventional ...

  7. Robert C. Seamans, Jr. Appointed to Lead Nuclear Weapons Program...

    National Nuclear Security Administration (NNSA)

    C. Seamans, Jr. Appointed to Lead Nuclear Weapons Program | National Nuclear Security Administration Facebook Twitter Youtube Flickr RSS People Mission Managing the Stockpile...

  8. NREL Ranks Leading Utility Green Power Programs - News Releases...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NREL Ranks Leading Utility Green Power Programs Pricing programs give consumers clean power choices April 3, 2007 The U.S. Department of Energy's (DOE) National Renewable Energy ...

  9. NREL Highlights Leading Utility Green Power Programs - News Releases...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NREL Highlights Leading Utility Green Power Programs March 4, 2004 Golden, Colo. - The U.S. Department of Energy's (DOE) National Renewable Energy Laboratory (NREL) today released ...

  10. Erratum: Leading-order calculation of electric conductivity in...

    Office of Scientific and Technical Information (OSTI)

    SciTech Connect Search Results Journal Article: Erratum: Leading-order calculation of electric conductivity in hot quantum electrodynamics from diagrammatic methods Phys. Rev. D ...

  11. Testing your home for lead in paint, dust, and soil

    SciTech Connect (OSTI)

    1998-10-01

    This publication is for anyone who is considering having a home or residence tested for lead in paint, dust, or soil by a professional. It explains the technical aspects of lead testing without overwhelming the reader. The first section tells why you would test for lead, the approaches for testing for lead, and what information you will get from each approach. The second section answers specific questions about how paint, soil, and dust sampling are conducted by the professional in your home. Finally, the last section answers other questions about testing, including questions about home test kits and testing of water and ceramics.

  12. New Superconducting Magnet Will Lead to Next Generation of Wind...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AML's design does not require a gearbox, which may lead to improved reliability and reduced maintenance costs. Although this may also be true for contemporary, gearbox-free ...

  13. NREL Leads Effort to Get Traffic Moving in Right Direction -...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NREL Leads Effort to Get Traffic Moving in Right Direction Connected Traveler project will guide travelers in energy-efficient manner August 17, 2015 The Energy Department's...

  14. Leading experts to speak at battery & energy storage technology...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Leading experts to speak at battery & energy storage technology conference Speakers from US Department of Energy, academia and industry to meet November 5th in Buffalo, NY News ...

  15. Huizenga leads safety of spent fuel management, radioactive waste...

    National Nuclear Security Administration (NNSA)

    Huizenga leads safety of spent fuel management, radioactive waste management meeting in Vienna | National Nuclear Security Administration Facebook Twitter Youtube Flickr RSS People...

  16. Cities Leading through Energy Analysis and Planning | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Us » Initiatives & Projects » Cities Leading through Energy Analysis and Planning Cities Leading through Energy Analysis and Planning <a href="/node/1142441">View this infographic</a> to learn more about the new Cities-LEAP report. View this infographic to learn more about the new Cities-LEAP report. The Cities Leading through Energy Analysis and Planning (Cities-LEAP) project delivers standardized, localized energy data and analysis that enables cities to lead clean

  17. Comparison of silatrane, phosphonic acid, and carboxylic acid functional

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    groups for attachment of porphyrin sensitizers to TiO2 in photoelectrochemical cells Comparison of silatrane, phosphonic acid, and carboxylic acid functional groups for attachment of porphyrin sensitizers to TiO2 in photoelectrochemical cells Authors: Brennan, B.J., Llansola Portoles, M.J., Liddell, P.A., Moore, T.A., Moore, A.L., and Gust, D. Title: Comparison of silatrane, phosphonic acid, and carboxylic acid functional groups for attachment of porphyrin sensitizers to TiO2 in

  18. ARM - Lesson Plans: Acid Rain

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Acid Rain Outreach Home Room News Publications Traditional Knowledge Kiosks Barrow, Alaska Tropical Western Pacific Site Tours Contacts Students Study Hall About ARM Global Warming FAQ Just for Fun Meet our Friends Cool Sites Teachers Teachers' Toolbox Lesson Plans Lesson Plans: Acid Rain Objective The objective is to help students understand the concept of acid rain and what impact this may have on vegetation. Materials Each group of students will need the following: 2 or 3 small plants of the

  19. Alternative Fuels Data Center: Conversion Regulations

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    Conversion Regulations to someone by E-mail Share Alternative Fuels Data Center: Conversion Regulations on Facebook Tweet about Alternative Fuels Data Center: Conversion Regulations on Twitter Bookmark Alternative Fuels Data Center: Conversion Regulations on Google Bookmark Alternative Fuels Data Center: Conversion Regulations on Delicious Rank Alternative Fuels Data Center: Conversion Regulations on Digg Find More places to share Alternative Fuels Data Center: Conversion Regulations on

  20. Acidic gas capture by diamines

    DOE Patents [OSTI]

    Rochelle, Gary (Austin, TX); Hilliard, Marcus (Missouri City, TX)

    2011-05-10

    Compositions and methods related to the removal of acidic gas. In particular, the present disclosure relates to a composition and method for the removal of acidic gas from a gas mixture using a solvent comprising a diamine (e.g., piperazine) and carbon dioxide. One example of a method may involve a method for removing acidic gas comprising contacting a gas mixture having an acidic gas with a solvent, wherein the solvent comprises piperazine in an amount of from about 4 to about 20 moles/kg of water, and carbon dioxide in an amount of from about 0.3 to about 0.9 moles per mole of piperazine.

  1. Drop In Fuels: Where the Road Leads | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Drop In Fuels: Where the Road Leads Drop In Fuels: Where the Road Leads Reviews key fuel industry drivers, renewable fuel mandates and projected impact on hydrocarbon fuels PDF icon deer11_wright.pdf More Documents & Publications New Directions in Fuels Technology EA-336 ConocoPhillips Company EA-336-A ConocoPhillips Company

  2. Water supplier copes with lead paint removal regs

    SciTech Connect (OSTI)

    Becker, C.E. ); Lovejoy, D.R.; Bryck, J.L.; Rockensies, W.H.

    1993-12-01

    This article examines new paint removal methods that minimize releasing of paints containing lead to the environment and lead free coating systems for tank corrosion protection used in the Village of Freeport in Long Island, New York. The topics of the article include coating failures, removal tools and methods, paint and application methods.

  3. Method for fabricating fan-fold shielded electrical leads

    DOE Patents [OSTI]

    Rohatgi, R.R.; Cowan, T.E.

    1994-12-27

    Fan-folded electrical leads made from copper cladded Kapton, for example, with the copper cladding on one side serving as a ground plane and the copper cladding on the other side being etched to form the leads. The Kapton is fan folded with the leads located at the bottom of the fan-folds. Electrical connections are made by partially opening the folds of the fan and soldering, for example, the connections directly to the ground plane and/or the lead. The fan folded arrangement produces a number of advantages, such as electrically shielding the leads from the environment, is totally non-magnetic, and has a very low thermal conductivity, while being easy to fabricate. 3 figures.

  4. Method for fabricating fan-fold shielded electrical leads

    DOE Patents [OSTI]

    Rohatgi, Rajeev R. (Mountain View, CA); Cowan, Thomas E. (Livermore, CA)

    1994-01-01

    Fan-folded electrical leads made from copper cladded Kapton, for example, with the copper cladding on one side serving as a ground plane and the copper cladding on the other side being etched to form the leads. The Kapton is fan folded with the leads located at the bottom of the fan-folds. Electrical connections are made by partially opening the folds of the fan and soldering, for example, the connections directly to the ground plane and/or the lead. The fan folded arrangement produces a number of advantages, such as electrically shielding the leads from the environment, is totally non-magnetic, and has a very low thermal conductivity, while being easy to fabricate.

  5. A new XRF method for measuring lead in paint

    SciTech Connect (OSTI)

    Grodzins, L.; Parsons, C.; Sackett, D.; Shefsky, S.; Tannian, B.

    1995-12-31

    The traditional field testing method for lead paint is the use of x-ray fluorescence, where the K shell fluorescence x-rays of lead (at 73 and 75 MeV) are measured. Although the K shell method can suffer from substrate effects and hence low sensitivity around the action level of 1 mg/cm{sup 2} of lead, it has been the industry choice because the effects of the overlying paint matrix on the K-shell x-rays are negligible. L shell x-rays of lead, at L{sub {alpha}} = 10.5 keV and L{sub {beta}} = 12.6 keV, provide much greater sensitivity and are free of substrate effects, but corrections for the absorption of the L-shell x-rays by the overlying non-lead paint matrix must be made. Such corrections were thought to be impossible without knowledge of the composition and thickness of the overlying paint matrix. NITON has developed a new method that makes it possible to use L-shell x-rays to accurately and quickly determine the absolute concentration of lead in buried lead paint (in mg/cm{sup 2}) without knowledge of the composition or thickness of the layers overlying the lead. The invention makes use of the fact that the ratio of the mass attenuation coefficients for the L{sub {alpha}} at 10.5 keV to the L{sub {beta}} at 12.6 keV is effectively independent of the elemental composition of paint layers. The new method also gives a measure of the depth of the lead beneath the surface. Theory and confirming experimental data will be presented. The authors will describe the NITON XL, a portable XRF device which uses the invention to give the lead concentration and its depth beneath the surface of paint.

  6. Environmental Regulations | Open Energy Information

    Open Energy Info (EERE)

    Regulations Jump to: navigation, search To do: add table This article is a stub. You can help OpenEI by expanding it. Retrieved from "http:en.openei.orgwindex.php?titleEnviron...

  7. APPARATUS FOR REGULATING HIGH VOLTAGE

    DOE Patents [OSTI]

    Morrison, K.G.

    1951-03-20

    This patent describes a high-voltage regulator of the r-f type wherein the modulation of the r-f voltage is accomplished at a high level, resulting in good stabilization over a large range of load conditions.

  8. Apparatus and methods for monitoring the concentrations of hazardous airborne substances, especially lead

    DOE Patents [OSTI]

    Zaromb, Solomon

    2004-07-13

    Air is sampled at a rate in excess of 100 L/min, preferably at 200-300 L/min, so as to collect therefrom a substantial fraction, i.e., at least 20%, preferably 60-100%, of airborne particulates. A substance of interest (analyte), such as lead, is rapidly solubilized from the the collected particulates into a sample of liquid extractant, and the concentration of the analyte in the extractant sample is determined. The high-rate air sampling and particulate collection may be effected with a high-throughput filter cartridge or with a recently developed portable high-throughput liquid-absorption air sampler. Rapid solubilization of lead is achieved by a liquid extractant comprising 0.1-1 M of acetic acid or acetate, preferably at a pH of 5 or less and preferably with inclusion of 1-10% of hydrogen peroxide. Rapid determination of the lead content in the liquid extractant may be effected with a colorimetric or an electroanalytical analyzer.

  9. Unique Auxin Regulation Mechanism Discovered

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Unique Auxin Regulation Mechanism Discovered Print The plant hormone auxin regulates many plant growth and development processes, including shoot growth, root branching, fruit ripening, tropisms, and flowering. But how such a simple molecule elicits such a variety of cellular responses has been a mystery. An important breakthrough came in 2005, wh en a conserved plant protein known as TIR1 (part of a protein destruction machinery system) was identified as a receptor for auxin. Now, an

  10. Unique Auxin Regulation Mechanism Discovered

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Unique Auxin Regulation Mechanism Discovered Print The plant hormone auxin regulates many plant growth and development processes, including shoot growth, root branching, fruit ripening, tropisms, and flowering. But how such a simple molecule elicits such a variety of cellular responses has been a mystery. An important breakthrough came in 2005, wh en a conserved plant protein known as TIR1 (part of a protein destruction machinery system) was identified as a receptor for auxin. Now, an

  11. Unique Auxin Regulation Mechanism Discovered

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Unique Auxin Regulation Mechanism Discovered Print The plant hormone auxin regulates many plant growth and development processes, including shoot growth, root branching, fruit ripening, tropisms, and flowering. But how such a simple molecule elicits such a variety of cellular responses has been a mystery. An important breakthrough came in 2005, wh en a conserved plant protein known as TIR1 (part of a protein destruction machinery system) was identified as a receptor for auxin. Now, an

  12. Unique Auxin Regulation Mechanism Discovered

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Unique Auxin Regulation Mechanism Discovered Print The plant hormone auxin regulates many plant growth and development processes, including shoot growth, root branching, fruit ripening, tropisms, and flowering. But how such a simple molecule elicits such a variety of cellular responses has been a mystery. An important breakthrough came in 2005, wh en a conserved plant protein known as TIR1 (part of a protein destruction machinery system) was identified as a receptor for auxin. Now, an

  13. Federal Regulations | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Federal Regulations Federal Regulations NOTE: Adobe Acrobat Reader may be necessary to view PDF documents listed below. Accessibility Section 508 of the Rehabilitation Act - Electronic and Information Technology Accessibility Standards Section 504 of the Rehabilitation Act - Nondiscrimination Under Federal Grants and Programs Federal Records Act Freedom of Information Act (as amended) Freedom of Information Act Updates Privacy Act of 1974 (as amended) Privacy Act Overview Cyber Security Atomic

  14. Federal Regulations | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Federal Regulations Federal Regulations keyboard-621831_960_720.jpg Cybersecurity Atomic Energy Act of 1954 (pdf) Computer Fraud and Abuse Act of 1986 Electronic Communications Privacy Act of 1986 Federal Information Security Management Act of 2002 (Title III of E-Gov) Homeland Security Act of 2002 (includes Cyber Security Act of 2002 and Critical Infrastructure Act of 2002) Uniting and Strengthening America by Providing Appropriate Tools Required to Intercept and Obstruct Terrorism Act Cyber

  15. Research, development, and demonstration of lead-acid batteries for electric-vehicle propulsion. Annual report, 1981

    SciTech Connect (OSTI)

    1982-03-01

    The progress of the design and development program is detailed. Results of drop tests, characteristics tests, and life cycle tests are presented and discussed. Results of tests of mechanical agitation of the electrolyte by air bubbling and an air lift pump are reported. Work on the electrode designs and electrolyte circulation systems is reported. (WHK)

  16. Prediction of epigenetically regulated genes in breast cancer cell lines

    SciTech Connect (OSTI)

    Loss, Leandro A; Sadanandam, Anguraj; Durinck, Steffen; Nautiyal, Shivani; Flaucher, Diane; Carlton, Victoria EH; Moorhead, Martin; Lu, Yontao; Gray, Joe W; Faham, Malek; Spellman, Paul; Parvin, Bahram

    2010-05-04

    Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation of CpG islands may silence associated genes. Therefore, using high-throughput microarrays to measure CpG island methylation will lead to better understanding of tumor pathobiology and progression, while revealing potentially new biomarkers. We have examined a recently developed high-throughput technology for measuring genome-wide methylation patterns called mTACL. Here, we propose a computational pipeline for integrating gene expression and CpG island methylation profles to identify epigenetically regulated genes for a panel of 45 breast cancer cell lines, which is widely used in the Integrative Cancer Biology Program (ICBP). The pipeline (i) reduces the dimensionality of the methylation data, (ii) associates the reduced methylation data with gene expression data, and (iii) ranks methylation-expression associations according to their epigenetic regulation. Dimensionality reduction is performed in two steps: (i) methylation sites are grouped across the genome to identify regions of interest, and (ii) methylation profles are clustered within each region. Associations between the clustered methylation and the gene expression data sets generate candidate matches within a fxed neighborhood around each gene. Finally, the methylation-expression associations are ranked through a logistic regression, and their significance is quantified through permutation analysis. Our two-step dimensionality reduction compressed 90% of the original data, reducing 137,688 methylation sites to 14,505 clusters. Methylation-expression associations produced 18,312 correspondences, which were used to further analyze epigenetic regulation. Logistic regression was used to identify 58 genes from these correspondences that showed a statistically signifcant negative correlation between methylation profles and gene expression in the panel of breast cancer cell lines. Subnetwork enrichment of these genes has identifed 35 common regulators with 6 or more predicted markers. In addition to identifying epigenetically regulated genes, we show evidence of differentially expressed methylation patterns between the basal and luminal subtypes. Our results indicate that the proposed computational protocol is a viable platform for identifying epigenetically regulated genes. Our protocol has generated a list of predictors including COL1A2, TOP2A, TFF1, and VAV3, genes whose key roles in epigenetic regulation is documented in the literature. Subnetwork enrichment of these predicted markers further suggests that epigenetic regulation of individual genes occurs in a coordinated fashion and through common regulators.

  17. Numerical Model for Conduction-Cooled Current Lead Heat Loads

    SciTech Connect (OSTI)

    White, M.J.; Wang, X.L.; Brueck, H.D.; /DESY

    2011-06-10

    Current leads are utilized to deliver electrical power from a room temperature junction mounted on the vacuum vessel to a superconducting magnet located within the vacuum space of a cryostat. There are many types of current leads used at laboratories throughout the world; however, conduction-cooled current leads are often chosen for their simplicity and reliability. Conduction-cooled leads have the advantage of using common materials, have no superconducting/normal state transition, and have no boil-off vapor to collect. This paper presents a numerical model for conduction-cooled current lead heat loads. This model takes into account varying material and fluid thermal properties, varying thicknesses along the length of the lead, heat transfer in the circumferential and longitudinal directions, electrical power dissipation, and the effect of thermal intercepts. The model is validated by comparing the numerical model results to ideal cases where analytical equations are valid. In addition, the XFEL (X-Ray Free Electron Laser) prototype current leads are modeled and compared to the experimental results from testing at DESY's XFEL Magnet Test Stand (XMTS) and Cryomodule Test Bench (CMTB).

  18. The Source of Airborne Lead: Recycling Pb-Contaminated Soils

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The Source of Airborne Lead: Recycling Pb-Contaminated Soils Starting in the 1970s, federal regulatory control and eventual elimination of lead-based "anti-knock" additives in gasoline decreased the level of airborne Pb in the USA by two orders-of-magnitude [1]. Blood lead levels of the USA figure 1 Figure 1. The good, the bad, and the ugly. Ambient airborne particulate matter captured on filters of woven silica fiber (large strips) and TeflonTM (round). Clean fiber filter at bottom

  19. Zinc halogen battery electrolyte composition with lead additive

    DOE Patents [OSTI]

    Henriksen, Gary L.

    1981-01-01

    This disclosure relates to a zinc halogen battery electrolyte composition containing an additive providing improved zinc-on-zinc recyclability. The improved electrolyte composition involves the use of a lead additive to inhibit undesirable irregular plating and reduce nodular or dendritic growth on the electrode surface. The lead-containing electrolyte composition of the present invention appears to influence not only the morphology of the base plate zinc, but also the morphology of the zinc-on-zinc replate. In addition, such lead-containing electrolyte compositions appear to reduce hydrogen formation.

  20. Energy Department Selects New Paducah Site Lead | Department of Energy

    Energy Savers [EERE]

    New Paducah Site Lead Energy Department Selects New Paducah Site Lead May 30, 2014 - 10:30am Addthis PADUCAH, Kentucky - The Department of Energy (DOE) Portsmouth Paducah Project Office (PPPO) is pleased to announce the selection of Mrs. Jennifer Woodard as the new Paducah Site Lead. Mrs. Woodard has over 20 years of experience in engineering and program/project management with the U.S. Department of Energy (DOE) and as a DOE contractor. Mrs. Woodard has a diverse background that includes

  1. Department of Energy Recognizes Six Leading Organizations for Helping the

    Energy Savers [EERE]

    U.S. 'Go Green' | Department of Energy Six Leading Organizations for Helping the U.S. 'Go Green' Department of Energy Recognizes Six Leading Organizations for Helping the U.S. 'Go Green' October 22, 2007 - 3:21pm Addthis 2007 National Green Power Supplier Award Winners WASHINGTON, DC - The U.S. Department of Energy (DOE) will recognize six leading organizations at the Seventh Annual Green Power Leadership Awards tonight in Philadelphia for advancing the development and use of "green

  2. Interference with BRCA2, which localizes to the centrosome during S and early M phase, leads to abnormal nuclear division

    SciTech Connect (OSTI)

    Nakanishi, Akira; Han, Xiangzi; Saito, Hiroko; Taguchi, Keiko; Ohta, Yoshiyasu; Imajoh-Ohmi, Shinobu; Miki, Yoshio; E-mail: miki.mgen@mri.tmd.ac.jp

    2007-03-30

    BRCA2 is responsible for familial breast and ovarian cancer, and its gene product is linked to DNA repair and transcriptional regulation. The BRCA2 protein exists mainly in the nucleus. Here, we show that BRCA2 has a centrosomal localization signal (CLS), localizes also to centrosomes during S and early M phases, and may regulate duplication and separation of the centrosomes. Green fluorescent protein (GFP) fused to the CLS peptides from BRCA2 (GFP-CLS) localizes to centrosomes and prevents endogenous BRCA2 from localizing to centrosomes. In addition, expression of GFP-CLS in cells leads to the abnormal duplication and positioning of centrosomes, resulting in the generation of multinuclear cells. These results thus implicate BRCA2 in the regulation of the centrosome cycle, and provide new insight into the aneuploid nature of many breast cancers.

  3. Post regulation circuit with energy storage

    DOE Patents [OSTI]

    Ball, Don G.; Birx, Daniel L.; Cook, Edward G.

    1992-01-01

    A charge regulation circuit provides regulation of an unregulated voltage supply and provides energy storage. The charge regulation circuit according to the present invention provides energy storage without unnecessary dissipation of energy through a resistor as in prior art approaches.

  4. Output-Based Regulations: A Handbook for Air Regulators (U.S...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Output-Based Regulations: A Handbook for Air Regulators (U.S. EPA), August 2004 Output-Based Regulations: A Handbook for Air Regulators (U.S. EPA), August 2004 The U.S....

  5. Kjiersten Fagnan Appointed NERSC/JGI Engagement Lead

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    to JGI staff and users. In addition, Fagnan will be the NERSC co-chair with Shane Canon, Group Lead for NERSC's Technology Integration Group, on the JGINERSC Coordinating...

  6. Engineer Russ Feder leads development of diagnostic tools for...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Russ Feder leads development of diagnostic tools for US ITER as physicist Dave Johnson shifts to part-time work By John Greenwald March 16, 2015 Tweet Widget Google Plus...

  7. Department of Energy Recognizes Six Leading Organizations for...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    October 22, 2007 - 3:21pm Addthis 2007 National Green Power Supplier Award Winners WASHINGTON, DC - The U.S. Department of Energy (DOE) will recognize six leading organizations at ...

  8. Method and apparatus for diagnosis of lead toxicity

    DOE Patents [OSTI]

    Rosen, John F. (Riverside, CT); Slatkin, Daniel N. (Bayside, NY); Wielopolski, Lucian (Shirley, NY)

    1989-01-01

    Improved methods and apparatus for in vivo measurement of the skeletal lead burden of a patient and for diagnosis of lead toxicity are disclosed. The apparatus comprises an x-ray tube emitting soft low energy x-rays from a silver anode, a polarizer for polarizing the emitted x-rays, and a detector for detecting photons fluoresced from atoms in the patient's tibia upon irradiation by the polarized x-rays. The fluoresced photons are spectrally analyzed to determine their energy distribution. Peaks indicating the presence of lead are identified if the patient has relatively high bone lead content. The data may be compared to data recorded with respect to a similar test performed on patients having also had the conventional EDTA chelation tests performed thereon in order to correlate the test results with respect to a particular patient to the conventionally accepted EDTA chelation test.

  9. Energy Secretary Bodman Leads US Delegation to International...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Secretary Bodman Leads US Delegation to International Energy Agency Ministerial May 2, 2005 - 12:41pm Addthis PARIS, FRANCE -- Secretary of Energy Samuel W. Bodman this week ...

  10. Women Engineers Lead Global Innovation in Bangalore | GE Global...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Lead Global Innovation in Bangalore Click to email this to a friend (Opens in new window) Share on Facebook (Opens in new window) Click to share (Opens in new window) Click to...

  11. Eliot Feibush leads new Princeton consortium to visualize Big...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Eliot Feibush leads new Princeton consortium to visualize Big Data By John Greenwald April 20, 2015 Tweet Widget Google Plus One Share on Facebook Eliot Feibush (Photo by Elle...

  12. Eliot Feibush leads new Princeton consortium to visualize Big...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Eliot Feibush leads new Princeton consortium to visualize Big Data By John Greenwald April 22, 2015 Tweet Widget Google Plus One Share on Facebook Eliot Feibush (Photo by Elle...

  13. Reexamination of Lead(II) Coordination Preferences in Sulfur...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    T.-C. Weng, & J.E. Penner-Hahn, University of Michigan J.S. Magyar & H.A. Godwin, Northwestern University Lead poisoning can damage the brain and nervous system and is particularly ...

  14. Updating about reductions of air and blood lead concentrations in Turin, Italy, following reductions in the lead content of gasoline

    SciTech Connect (OSTI)

    Bono, R.; Pignata, C.; Gilli, G.

    1995-07-01

    Considering its well known toxicity and the chronic human exposure to lead, international lawmakers enforced some directives or laws calling for the reduction of lead content in gasoline. All of these legislative acts aimed to reduce health risks for the general population. The aim of this study was to consider the effectiveness of these laws on air lead levels and consequently on blood lead levels in a randomly selected urban Italian population. In particular, these markers were analyzed over the course of several years, corresponding to the periods just before and after enforcements of the reductions of lead in petrol. Data presented point out some considerations: (1) enforcement of legislative measures concerning the reduction of lead in petrol has reduced atmospheric levels of lead. This result demonstrates a major environmental success in primary prevention efforts. (2) This success is clear especially considering that the actual Pb-B levels can be extended to the urbanized populations. Pb-B levels were consistently higher for drinkers, for older adults and for males. The mean of Pb-B level for the present urbanized population is higher than the U.S. overall population (6.4 vs 3 {mu}g/dl). This difference can be also explained considering the different historical period of enforcement of the restriction laws. 10 refs., 3 figs., 3 tabs.

  15. Volunteers Leading Technology, A Case Study: Chewonki Renewable Hydrogen

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Project | Department of Energy Volunteers Leading Technology, A Case Study: Chewonki Renewable Hydrogen Project Volunteers Leading Technology, A Case Study: Chewonki Renewable Hydrogen Project This presentation by Paul Faulstich focuses on the Chewonki Renewable Hydrogen Project. PDF icon education_presentation_faulstich.pdf More Documents & Publications EIS-0073: Final Environmental Impact Statement EIS-0063: Final Environmental Impact Statement EIS-0063: Draft Environmental Impact

  16. Secretaries Chu and Salazar Lead Administration Team Offering Federal

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Scientific and Technological Support to BP Engineers | Department of Energy Lead Administration Team Offering Federal Scientific and Technological Support to BP Engineers Secretaries Chu and Salazar Lead Administration Team Offering Federal Scientific and Technological Support to BP Engineers May 12, 2010 - 12:00am Addthis HOUSTON, TX -- At the request of the President, Secretary Chu and Secretary Salazar traveled to Houston today to participate in meetings with DOE and national lab staff,

  17. Hydrostatic pressure-induced modifications of structural transitions lead

    Office of Scientific and Technical Information (OSTI)

    to large enhancements of magnetocaloric effects in MnNiSi-based systems (Journal Article) | DOE PAGES Hydrostatic pressure-induced modifications of structural transitions lead to large enhancements of magnetocaloric effects in MnNiSi-based systems « Prev Next » Title: Hydrostatic pressure-induced modifications of structural transitions lead to large enhancements of magnetocaloric effects in MnNiSi-based systems Authors: Samanta, Tapas ; Lepkowski, Daniel L. ; Saleheen, Ahmad Us ; Shankar,

  18. Lead Slowing Down Spectrometry Analysis of Data from Measurements on

    Office of Scientific and Technical Information (OSTI)

    Nuclear Fuel (Journal Article) | SciTech Connect Journal Article: Lead Slowing Down Spectrometry Analysis of Data from Measurements on Nuclear Fuel Citation Details In-Document Search Title: Lead Slowing Down Spectrometry Analysis of Data from Measurements on Nuclear Fuel Improved non-destructive assay of isotopic masses in used nuclear fuel would be valuable for nuclear safeguards operations associated with the transport, storage and reprocessing of used nuclear fuel. Our collaboration is

  19. Leading Edge Technology in Diesel Emissions Control | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Leading Edge Technology in Diesel Emissions Control Leading Edge Technology in Diesel Emissions Control Poster presented at the 16th Directions in Engine-Efficiency and Emissions Research (DEER) Conference in Detroit, MI, September 27-30, 2010. PDF icon p-02_roberts.pdf More Documents & Publications NO2 Management in Diesel Exhaust System Experimental Evaluation of DOC Performance Using Secondary Fuel Injection Low Temperature Catalyst for Fuel Injection System

  20. Leading by Example: Better Buildings Challenge Partners Cut Energy Use |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Leading by Example: Better Buildings Challenge Partners Cut Energy Use Leading by Example: Better Buildings Challenge Partners Cut Energy Use May 22, 2013 - 12:00pm Addthis New infographic breaks down the data companies submitted for the first year of the Better Buildings Challenge. | Infographic by Sarah Gerrity, Energy Department. New infographic breaks down the data companies submitted for the first year of the Better Buildings Challenge. | Infographic by Sarah

  1. Downregulation of Cinnamyl Alcohol Dehydrogenase (CAD) Leads to Improved

    Office of Scientific and Technical Information (OSTI)

    Saccharification Efficiency in Switchgrass (Journal Article) | SciTech Connect Downregulation of Cinnamyl Alcohol Dehydrogenase (CAD) Leads to Improved Saccharification Efficiency in Switchgrass Citation Details In-Document Search Title: Downregulation of Cinnamyl Alcohol Dehydrogenase (CAD) Leads to Improved Saccharification Efficiency in Switchgrass Authors: Chunxiang,Fu ; Xirong,Xiao ; Yajun,Xi ; Yaxin,Ge ; Fang,Chen ; Joseph,Bouton ; Richard A.,Dixon ; Zeng-Yu,Wang ; , Publication Date:

  2. Moderate Doping Leads to High Performance of Semiconductor/Insulator

    Office of Scientific and Technical Information (OSTI)

    Polymer Blend Transistors (Journal Article) | SciTech Connect Journal Article: Moderate Doping Leads to High Performance of Semiconductor/Insulator Polymer Blend Transistors Citation Details In-Document Search Title: Moderate Doping Leads to High Performance of Semiconductor/Insulator Polymer Blend Transistors Authors: Lu, Guanghao ; Blakesley, James ; Himmelberger, Scott ; Pingel, Patrick ; Frisch, Johannes ; Lieberwirth, Ingo ; Salzmann, Ingo ; Oehzelt, Martin ; Pietro, Riccardo Di ;

  3. Obama Administration Announces Members of Steering Team to Lead Interagency

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Coordination of Unconventional Oil and Gas Research and Development | Department of Energy Members of Steering Team to Lead Interagency Coordination of Unconventional Oil and Gas Research and Development Obama Administration Announces Members of Steering Team to Lead Interagency Coordination of Unconventional Oil and Gas Research and Development May 24, 2012 - 3:49pm Addthis Bill Gibbons Press Secretary, Office of Public Affairs Who Will Represent the Energy Department? Christopher Smith,

  4. United States Regains Lead with World's Fastest Supercomputer |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy States Regains Lead with World's Fastest Supercomputer United States Regains Lead with World's Fastest Supercomputer June 18, 2012 - 2:02pm Addthis NEWS MEDIA CONTACT (202) 586-4940 WASHINGTON - Energy Secretary Steven Chu today announced that a supercomputer called Sequoia at Lawrence Livermore National Laboratory (LLNL) in Livermore, California, received the rank of the world's most powerful computing system. The Top500 list, which annually ranks the world's fastest

  5. University Teams Lead Innovative Solar Research Projects | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Lead Innovative Solar Research Projects University Teams Lead Innovative Solar Research Projects August 28, 2012 - 2:55pm Addthis A concentrating solar power system in Albuquerque, New Mexico. | Photo by Randy Montoya/Sandia National Laboratory. A concentrating solar power system in Albuquerque, New Mexico. | Photo by Randy Montoya/Sandia National Laboratory. Erin R. Pierce Erin R. Pierce Former Digital Communications Specialist, Office of Public Affairs What are the key facts? The

  6. Richard Gerber Named New NERSC User Services Group Lead

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Richard Gerber New NERSC User Services Group Lead Richard Gerber Named New NERSC User Services Group Lead December 12, 2013 RichardGerber.jpg Richard Gerber Richard Gerber has been named leader of the NERSC User Services Group (USG), effective immediately. He takes over for Katie Antypas, who was appointed head of the NERSC Services Department in September. In his new role, Gerber will be responsible for managing a group that works to increase the scientific productivity of NERSC's 4,700 users.

  7. DOE-Idaho Leads Regional Combined Federal Campaign

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    DOE NEWS RELEASE DOE-Idaho Leads Regional Combined Federal Campaign FOR IMMEDIATE RELEASE December 5, 2007 Media Contact: Brad Bugger, (208) 526-8484 The U.S. Department of Energy's Idaho Operations Office is once again leading the regional Combined Federal Campaign, which is the only sanctioned charitable campaign for all federal employees. Idaho Operations Office staff evaluates applications from local non-profit organizations who want to be included in the Combined Federal Campaign, to make

  8. Facilities Electrician & Lead Electrician | Princeton Plasma Physics Lab

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Electrician & Lead Electrician Department: Engineering Supervisor(s): John Lacenere Staff: TSS 04 & 05 Requisition Number: 1600206 (POOL JOB, SOURCE REQUISITION) Position Summary: The Princeton University Plasma Physics Laboratory, a world-renowned fusion energy research center under contract with the U. S. Department of Energy is seeking to hire a: *Facilities Electrician (Grade, TSS 04, one-year term position) and a *Facilities LEAD Electrician (Grade, TSS 05). Our electricians will

  9. Construction Branch Electrician & Lead Electrician | Princeton Plasma

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Physics Lab Construction Branch Electrician & Lead Electrician Department: Engineering Supervisor(s): Frank Jones Staff: TSS 04 & 05 Requisition Number: 1600208 (POOL JOB, SOURCE REQUISITION) Position Summary: The Princeton University Plasma Physics Laboratory, a world-renowned fusion energy research center under contract with the U. S. Department of Energy is seeking to hire a: *Facilities Electrician (Grade, TSS 04, one-year term position) and a *Facilities LEAD Electrician (Grade,

  10. Cooperative Catalyst leads to Transformative Results | The Ames Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Cooperative Catalyst leads to Transformative Results Capitalizing on the concept that everything proceeds faster with a little cooperation, researchers showed how designing cooperation into solid catalysts leads to enormous benefits.Catalysts attached to a porous solid support are preferred industrially because they are easier to separate from liquid products and reuse. But, these bound catalysts typically do not perform as well and probing their interiors to figure out how to improve them has

  11. Excellence in Energy Awards: Military Academies Leading by Example |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Excellence in Energy Awards: Military Academies Leading by Example Excellence in Energy Awards: Military Academies Leading by Example May 15, 2014 - 9:55am Addthis Federal Energy Management Program Director Dr. Timothy Unruh (fourth from left) with Air Force Academy staff and students. The Air Force Academy team won a DOE Excellence in Energy Award for their microgrid design that featured two biomass-fired combined heat & power facilities, fuel cells, and a complex

  12. University Competition Leads to Geothermal Breakthroughs | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Competition Leads to Geothermal Breakthroughs University Competition Leads to Geothermal Breakthroughs March 8, 2013 - 11:57am Addthis Idaho State University's National Geothermal Student Competition team presenting their research findings at the 2012 Geothermal Resources Council spring/summer meeting. | Photo courtesy of the Geothermal Resources Council. Idaho State University's National Geothermal Student Competition team presenting their research findings at the 2012 Geothermal

  13. Resonant bonding leads to low lattice thermal conductivity (Journal

    Office of Scientific and Technical Information (OSTI)

    Article) | SciTech Connect Resonant bonding leads to low lattice thermal conductivity Citation Details In-Document Search Title: Resonant bonding leads to low lattice thermal conductivity Authors: Lee, S Y ; Esfarjani, Keivan ; Luo, T. ; Zhou, J ; Tian, Z ; Chen, Gang Publication Date: 2014-04-28 OSTI Identifier: 1161924 DOE Contract Number: SC0001299; FG02-09ER46577 Resource Type: Journal Article Resource Relation: Journal Name: Nature Communications; Journal Volume: 5; Related Information:

  14. Strongly Coupled Data Assimilation Using Leading Averaged Coupled

    Office of Scientific and Technical Information (OSTI)

    Covariance (LACC). Part II: CGCM experiments (Journal Article) | SciTech Connect Strongly Coupled Data Assimilation Using Leading Averaged Coupled Covariance (LACC). Part II: CGCM experiments Citation Details In-Document Search Title: Strongly Coupled Data Assimilation Using Leading Averaged Coupled Covariance (LACC). Part II: CGCM experiments Authors: Liu, Feiyu ; Liu, Zhengyu ; Zhang, S. ; Liu, Y. ; Jacob, Robert L. Publication Date: 2015-11-01 OSTI Identifier: 1237902 DOE Contract Number:

  15. Surface Plasmon Instability Leading to Emission of Radiation. (Journal

    Office of Scientific and Technical Information (OSTI)

    Article) | SciTech Connect Surface Plasmon Instability Leading to Emission of Radiation. Citation Details In-Document Search Title: Surface Plasmon Instability Leading to Emission of Radiation. Abstract not provided. Authors: Gumbs, Godfrey ; Iurov, Andrii ; Huang, Danhong ; Pan, Wei Publication Date: 2014-11-01 OSTI Identifier: 1184587 Report Number(s): SAND2014-19499J 541018 DOE Contract Number: AC04-94AL85000 Resource Type: Journal Article Resource Relation: Journal Name: Physical Review

  16. Update on Establishing the Feasibility of Lead Slowing Down Spectroscopy

    Office of Scientific and Technical Information (OSTI)

    for Direct Measurement of Plutonium in Used Fuel (Conference) | SciTech Connect Conference: Update on Establishing the Feasibility of Lead Slowing Down Spectroscopy for Direct Measurement of Plutonium in Used Fuel Citation Details In-Document Search Title: Update on Establishing the Feasibility of Lead Slowing Down Spectroscopy for Direct Measurement of Plutonium in Used Fuel Developing a method for the accurate, direct, and independent assay of the fissile isotopes in bulk materials (such

  17. Honeymoons Lead to Upgrades in Western Vermont | Department of Energy

    Energy Savers [EERE]

    Honeymoons Lead to Upgrades in Western Vermont Honeymoons Lead to Upgrades in Western Vermont Logo Neighborworks H.E.A.T. Squad. For homeowners who are hesitant to make energy efficiency upgrades, offering them a honeymoon might just be the motivation they need. NeighborWorks of Western Vermont (NWWVT) created a "honeymoon period" for its loan payments and has seen success by allowing homeowners to experience six months of comfort and energy savings before they begin making loan

  18. Imagine Tomorrow: Student Competition Leads to Innovative Biofuel Ideas |

    Energy Savers [EERE]

    Department of Energy Imagine Tomorrow: Student Competition Leads to Innovative Biofuel Ideas Imagine Tomorrow: Student Competition Leads to Innovative Biofuel Ideas May 28, 2014 - 9:20am Addthis Watch the video above to learn more about the Imagine Tomorrow competition. Leslie Ovard Bioenergy Policy Specialist, Bioenergy Technologies Office Can you imagine if solar panels could be used to grow algae for fuel? Or if your morning coffee could not only get your day started, but also serve as a

  19. Partnership between DOE programs leads to mutual success | Department of

    Energy Savers [EERE]

    Energy Partnership between DOE programs leads to mutual success Partnership between DOE programs leads to mutual success January 30, 2015 - 9:19am Addthis Pictured left to right at the Bear Creek Burial Ground are UCOR representatives Paul Waldschlager and Sherree Shaw, UCOR President Ken Rueter, OREM Manager Sue Cange, UPF Federal Project Director John Eschenberg, and CNS representatives Brian Reilly, Lynn Nolan and John Stone. Pictured left to right at the Bear Creek Burial Ground are UCOR

  20. PNNL Breakthrough Leads to Less Foreign Oil, More American Jobs |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy PNNL Breakthrough Leads to Less Foreign Oil, More American Jobs PNNL Breakthrough Leads to Less Foreign Oil, More American Jobs October 17, 2011 - 2:50pm Addthis A highly efficient catalyst to convert renewable crops into the product propylene glycol was discovered by scientists at the Pacific Northwest National Laboratory (PNNL) and commercialized by the Archer Daniels Midland Company. | Image courtesy of PNNL. A highly efficient catalyst to convert renewable crops into

  1. Leading the Charge: Chairman Vig Champions Progress, Sustainability |

    Office of Environmental Management (EM)

    Department of Energy Chairman Vig Champions Progress, Sustainability Leading the Charge: Chairman Vig Champions Progress, Sustainability October 20, 2014 - 5:00pm Addthis A photo of Chairman Vig. Change doesn't happen on its own. It's led by dedicated and passionate people who are committed to empowering Indian Country to energize future generations. Leading the Charge is a regular feature spotlighting the movers and shakers in energy on tribal lands. This issue we had the opportunity to

  2. High Efficiency Microturbine Leads to Increased Market Share | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of Energy High Efficiency Microturbine Leads to Increased Market Share High Efficiency Microturbine Leads to Increased Market Share April 18, 2013 - 12:00am Addthis Partnering with Capstone Turbine Corporation of Chatsworth, EERE supported microturbine research and development for a combined heat and power system that led to the commercialization of that product. Capstone increased electrical efficiency of the unit from about 17%-22% to 33%, and it has seen more than $83 million in revenue

  3. Institute for Advanced Composites Helping America Lead on Clean Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Manufacturing | Department of Energy Institute for Advanced Composites Helping America Lead on Clean Energy Manufacturing Institute for Advanced Composites Helping America Lead on Clean Energy Manufacturing June 18, 2015 - 4:28pm Addthis Assistant Secretary for Energy Efficiency and Renewable Energy Dr. David Danielson speaks during the launch of the Institute for Advanced Composites Manufacturing Innovation in Knoxville, Tennessee. | Photo courtesy of Oak Ridge National Laboratory.

  4. Lab Breakthrough: Fusion Research Leads to Antiterrorism Device |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Fusion Research Leads to Antiterrorism Device Lab Breakthrough: Fusion Research Leads to Antiterrorism Device June 26, 2012 - 12:17pm Addthis Researchers at the Princeton Plasma Physics Laboratory developed an antiterrorism device that can detect and identify sources of dangerous radiation that could be used in a dirty bomb. See the other Lab Breakthrough videos on the YouTube playlist. Michael Hess Michael Hess Former Digital Communications Specialist, Office of Public

  5. Lab Breakthrough: Nanomaterials Discoveries Lead to Possible Cancer

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Treatment | Department of Energy Nanomaterials Discoveries Lead to Possible Cancer Treatment Lab Breakthrough: Nanomaterials Discoveries Lead to Possible Cancer Treatment June 4, 2012 - 3:05pm Addthis Argonne nanoscientist Elena Rozhkova is studying ways to enlist nanoparticles to treat brain cancer. This nano-bio technology may eventually provide an alternative form of therapy that targets only cancer cells and does not affect normal living tissue. View the entire Lab Breakthrough playlist.

  6. DOE - Office of Legacy Management -- United Lead Co - NJ 29

    Office of Legacy Management (LM)

    Lead Co - NJ 29 FUSRAP Considered Sites Site: United Lead Co. (NJ.29 ) Designated Name: Alternate Name: Location: Evaluation Year: Site Operations: Site Disposition: Radioactive Materials Handled: Primary Radioactive Materials Handled: Radiological Survey(s): Site Status: This site is one of a group of 77 FUSRAP considered sites for which few, if any records are available in their respective site files to provide an historical account of past operations and their relationship, if any, with

  7. A Minority Serving Institution Leads the Way in Better Buildings |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy A Minority Serving Institution Leads the Way in Better Buildings A Minority Serving Institution Leads the Way in Better Buildings July 5, 2012 - 6:06pm Addthis Secretary Chu visits Delaware State University to commemorate the school's efforts with the Better Buildings Initiative. Secretary Chu visits Delaware State University to commemorate the school's efforts with the Better Buildings Initiative. Dot Harris Dot Harris Director, Office of Economic Impact and Diversity

  8. Solar Decathlon 2015: Nation's Leading Sustainable Home Design

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Competition on the Horizon | Department of Energy Nation's Leading Sustainable Home Design Competition on the Horizon Solar Decathlon 2015: Nation's Leading Sustainable Home Design Competition on the Horizon July 13, 2015 - 2:15pm Addthis The New York City College of Technology is weatherproofing its house, called DURA, at a Brooklyn Navy Yard construction site. | Photo courtesy of New York City College of Technology. The New York City College of Technology is weatherproofing its house,

  9. Dr. Sanjiv Malhotra to Lead Energy Department's Clean Energy Investment

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Center | Department of Energy Dr. Sanjiv Malhotra to Lead Energy Department's Clean Energy Investment Center Dr. Sanjiv Malhotra to Lead Energy Department's Clean Energy Investment Center January 5, 2016 - 4:28pm Addthis News Media Contact 202-586-4940 DOENews@hq.doe.gov WASHINGTON - The U.S. Department of Energy (DOE) announced today that Dr. Sanjiv Malhotra will be the first Director of the Clean Energy Investment Center (CEIC), located within the Office of Technology Transitions (OTT).

  10. EM's Portsmouth Site Donations Lead to Food Pantry Reopening | Department

    Office of Environmental Management (EM)

    of Energy EM's Portsmouth Site Donations Lead to Food Pantry Reopening EM's Portsmouth Site Donations Lead to Food Pantry Reopening September 6, 2013 - 2:58pm Addthis Community Action Committee Senior/Social/Transit Assistant Program Director Pamela Crawford unloads pantry donations from EM’s Portsmouth site employees. | Photos courtesy of the Office of Environmental Management. Community Action Committee Senior/Social/Transit Assistant Program Director Pamela Crawford unloads pantry

  11. Earth Day: Leading by Example | Department of Energy

    Office of Environmental Management (EM)

    Day: Leading by Example Earth Day: Leading by Example April 20, 2012 - 11:40am Addthis Michael Dunn, Deputy Director of Facilities Management at Argonne National Laboratory, setup a program that encouraged employees to cut their energy use during peak summer months and resulted in more than $475,000 in savings. Here he stands next to an electrical vehicle fueling station that charges cars with solar energy. | Image courtesy of Argonne National Laboratory. Michael Dunn, Deputy Director of

  12. International Electricity Regulation | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Regulation International Electricity Regulation U.S. trade in electric energy with Canada and Mexico is rising, bringing economic and reliability benefits to the United States and ...

  13. Fish Habitat Regulations | Open Energy Information

    Open Energy Info (EERE)

    Fish Habitat Regulations Jump to: navigation, search OpenEI Reference LibraryAdd to library Web Site: Fish Habitat Regulations Author Alaska Department of Fish & Game Published...

  14. Alaska ADEC Wetlands Regulation | Open Energy Information

    Open Energy Info (EERE)

    Wetlands Regulation Jump to: navigation, search OpenEI Reference LibraryAdd to library Web Site: Alaska ADEC Wetlands Regulation Author Alaska Division of Water Published Alaska...

  15. Lead in human blood from children living in Campania, Italy

    SciTech Connect (OSTI)

    Amodio-Cocchieri, R.; Arnese, A.; Prospero, E.; Roncioni, A.

    1996-03-01

    Blood lead (PbB) levels were determined in children living Campania (in Naples and in a rural zone in the district of Caserta). Atmospheric lead (PbA) concentration in these considered areas was monitored for 1 yr (1993-1994). The children tested were questioned about common sources of lead, other than atmospheric relating to their living and dietary habits. The PbB levels in children living in Naples were at the 50th percentile, 18.8 {mu}g/dl in males and 13.7 {mu}g/dl in females; in children living in the rural area the median PbB levels were 8.9{mu}g/dl in males, and 9.9 {mu}g/dl in females. The annual mean values of atmospheres lead were 1.15 {plus_minus} 0.24 {mu}g/dl in Naples and 0.23 {plus_minus} 0.07 {mu}g/dl in the rural area. Significant and congruent mean differences between urban and rural sites were found in children`s blood and concurrent air lead. Considering the PbB level of 10 {mu}g/dl as the maximum level that is not associated any known adverse effect in children, the Neapolitan group can be considered at risk of chronic intoxication by lead. 18 refs., 3 figs., 4 tabs.

  16. Glass composition development for stabilization of lead based paints

    SciTech Connect (OSTI)

    Marra, J.C.

    1996-10-01

    Exposure to lead can lead to adverse health affects including permanent damage to the central nervous system. Common means of exposure to lead are from ingestion of lead paint chips or breathing of dust from deteriorating painted surfaces. The U.S. Army has over 101 million square feet of buildings dating to World War II or earlier. Many of these structures were built before the 1978 ban on lead based paints. The U.S. Army Corps of Engineers CERL is developing technologies to remove and stabilize lead containing organic coatings. Promising results have been achieved using a patented flame spray process that utilizes a glass frit to stabilize the hazardous constituents. When the glass frit is sprayed onto the paint containing substrate, differences in thermal expansion coefficients between the frit and the paint results in spalling of the paint from the substrate surface. The removed fragments are then collected and remelted to stabilize the hazardous constituents and allow for disposal as non-hazardous waste. Similar successful results using a patented process involving microwave technology for paint removal have also been achieved. In this process, the painted surface is coated with a microwave coupling compound that when exposed to microwave energy results in the spalling of the hazardous paint from the surface. The fragments can again be accumulated and remelted for stabilization and disposal.

  17. MERCURY AND LEAD SAMPLING AT MINNESOTA POWER'S BOSWELL ENERGY CENTER

    SciTech Connect (OSTI)

    Dennis L. Laudal

    2000-08-01

    At the request of the Minnesota Power, Inc., the Energy & Environmental Research Center (EERC) sampled for lead at the stack (or duct directly leading to the stack) for three units at the Boswell Energy Center. All sampling was done in triplicate using U.S. Environmental Protection Agency (EPA) Method 12, with sampling procedures following EPA Methods 1 through 4. During the test program, lead sampling was done using EPA Method 12 in the duct at the outlet of the baghouse serving Unit 2 and the duct at the outlet of the wet particulate scrubber serving Unit 3. For Unit 4, lead sampling was done at the stack. The specific objective for the project was to determine the concentration of lead in the flue gas being emitted into the atmosphere from the Boswell Energy Center. The test program was performed during the period of May 8 through 11, 2000. This report presents the test data, sample calculations, and results, and a discussion of the lead sampling performed at the Boswell Energy Center. The detailed test data and test results, raw test data, process data, laboratory reports, and equipment calibration records are provided in Appendices A, B, and C.

  18. Vitrification of lead-based paint using thermal spray

    SciTech Connect (OSTI)

    Kumar, A.; Covey, S.W.; Lattimore, J.L.; Boy, J.H.

    1996-12-31

    Lead-based paint (LBP) primers have been used to protect steel structures from corrosion. Abrasive blasting is currently used to remove old LBP. During abrasive blasting a containment structure is required to keep the hazardous lead dust from contaminating air, soil, or water. A thermal spray vitrification (TSV) process to remove LBP was developed. Dried glass powder is melted in the high temperature flame of the thermal spray torch. When the glass strikes the substrate it is molten and reacts with the paint on the substrate. The organic components of the paint are pyrolyzed, while the lead ions are trapped on the surface of glass. The quenching stresses in the glass cause the glass to crack and spall off the substrate. The crumbled glass fragments can be collected and remelted, immobilizing the lead ions within the glass network, thereby preventing leaching. The resulting glass can be disposed of as non-hazardous waste. The process is dust-free, eliminating the need for containment. The volume of residue waste is less than for abrasive blasting and is nonhazardous. The concept and techniques of using the thermal spray vitrification process for the removal and the containment of lead from a section of a bridge containing lead-based paint have been successfully demonstrated.

  19. ISOs: The new antitrust regulators?

    SciTech Connect (OSTI)

    Raskin, D.B.

    1998-04-01

    Fear of seller market power in emerging electricity markets has led regulators to sanction use of independent system operators as private market police. A more restrained approach is likely to yield better results without the chilling effects of private regulation. This new industry regulatory paradigm has received little critical attention to date. This is unfortunate because ISO antitrust regulation raises serious legal and policy concerns. The California and New England Power Pool (NEPOOL) plans are quite intrusive. They require the ISO to make difficult distinctions between acceptable and unacceptable market behavior. They create considerable risk that desirable competitive behavior will be chilled and that market participants will incur significant explicit and implicit costs to meet regulatory requirements.

  20. PRODUCTION OF TRIFLUOROACETIC ACID COMPOUNDS

    DOE Patents [OSTI]

    Haworth, W.N.; Stacey, M.

    1949-08-30

    A process is described for the preparation of trifluoroacetic acid. Acetone vapor diluted wlth nitrogen and fluorine also diluted with nltrogen are fed separately at a temperature of about 210 deg C into a reaction vessel containing a catalyst mass selected from-the group consisting of silver and gold. The temperature in the reaction vessel is maintained in the range of 200 deg to 250 deg C. The reaction product, trifluoroacetyl fluoride, is absorbed in aqueous alkali solution. Trifluoroacetic acid is recovered from the solution by acidification wlth an acid such as sulfuric followed by steam distillation.

  1. Lead-free and lead-based ABO3 perovskite relaxors with mixed-valence A-site

    Office of Scientific and Technical Information (OSTI)

    and B-site disorder: A comparative neutron scattering structural study of (Na1/2Bi1/2)TiO3 and Pb(Mg1/3Nb2/3)O3 (Journal Article) | SciTech Connect Lead-free and lead-based ABO3 perovskite relaxors with mixed-valence A-site and B-site disorder: A comparative neutron scattering structural study of (Na1/2Bi1/2)TiO3 and Pb(Mg1/3Nb2/3)O3 Citation Details In-Document Search Title: Lead-free and lead-based ABO3 perovskite relaxors with mixed-valence A-site and B-site disorder: A comparative

  2. Better Buildings Residential Network Peer Exchange Call Series: Generating Energy Efficiency Project Leads and Allocating Leads to Contractors

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Generating Energy Efficiency Project Leads and Allocating Leads to Contractors Call Slides and Discussion Summary February 26, 2015 Call Participants  Build It Green  City of Chula Vista  City of Philadelphia  Civic Works/Retrofit Baltimore  Clean Energy Durham  Clean Energy Works  Community Office for Resource Efficiency  Dr. Energy Saver  Efficiency Maine  Efficiency Nova Scotia  Energy Efficiency Specialists, LLC  Energy Pioneer Solutions  Greater

  3. An ortholog of farA of Aspergillus nidulans is implicated in the transcriptional activation of genes involved in fatty acid utilization in the yeast Yarrowia lipolytica

    SciTech Connect (OSTI)

    Poopanitpan, Napapol; Kobayashi, Satoshi; Fukuda, Ryouichi; Horiuchi, Hiroyuki; Ohta, Akinori

    2010-11-26

    Research highlights: {yields} POR1 is a Yarrowia lipolytica ortholog of farA involved in fatty acid response in A. nidulans. {yields} Deletion of POR1 caused growth defects on fatty acids. {yields} {Delta}por1 strain exhibited defects in the induction of genes involved in fatty acid utilization. -- Abstract: The yeast Yarrowia lipolytica effectively utilizes hydrophobic substrates such as fatty acids and n-alkanes. To identify a gene(s) regulating fatty acid utilization in Y. lipolytica, we first studied homologous genes to OAF1 and PIP2 of Saccharomyces cerevisiae, but their disruption did not change growth on oleic acid at all. We next characterized a Y. lipolytica gene, POR1 (primary oleate regulator 1), an ortholog of farA encoding a transcriptional activator that regulates fatty acid utilization in Aspergillus nidulans. The deletion mutant of POR1 was defective in the growth on various fatty acids, but not on glucose, glycerol, or n-hexadecane. It exhibited slight defect on n-decane. The transcriptional induction of genes involved in {beta}-oxidation and peroxisome proliferation by oleate was distinctly diminished in the {Delta}por1 strains. These data suggest that POR1 encodes a transcriptional activator widely regulating fatty acid metabolism in Y. lipolytica.

  4. Phosphonic acid based exchange resins

    DOE Patents [OSTI]

    Horwitz, E.P.; Alexandratos, S.D.; Gatrone, R.C.; Chiarizia, R.

    1995-09-12

    An ion exchange resin is described for extracting metal ions from a liquid waste stream. An ion exchange resin is prepared by copolymerizing a vinylidene diphosphonic acid with styrene, acrylonitrile and divinylbenzene. 10 figs.

  5. Phosphonic acid based exchange resins

    DOE Patents [OSTI]

    Horwitz, E. Philip; Alexandratos, Spiro D.; Gatrone, Ralph C.; Chiarizia, Ronato

    1995-01-01

    An ion exchange resin for extracting metal ions from a liquid waste stream. An ion exchange resin is prepared by copolymerizing a vinylidene diphosphonic acid with styrene, acrylonitrile and divinylbenzene.

  6. Genome sequencing of the Trichoderma reesei QM9136 mutant identifies a truncation of the transcriptional regulator XYR1 as the cause for its cellulase-negative phenotype

    SciTech Connect (OSTI)

    Lichius, Alexander; Bidard, Frederique; Buchholz, Franziska; Le Crom, Stphane; Martin, Joel X.; Schackwitz, Wendy; Austerlitz, Tina; Grigoriev, Igor V.; Baker, Scott E.; Margeot, Antoine; Seiboth, Bernhard; Kubicek, Christian P.

    2015-12-01

    Background: Trichoderma reesei is the main industrial source of cellulases and hemicellulases required for the hydrolysis of biomass to simple sugars, which can then be used in the production of biofuels and biorefineries. The highly productive strains in use today were generated by classical mutagenesis. As byproducts of this procedure, mutants were generated that turned out to be unable to produce cellulases. In order to identify the mutations responsible for this inability, we sequenced the genome of one of these strains, QM9136, and compared it to that of its progenitor T. reesei QM6a. Results: In QM9136, we detected a surprisingly low number of mutagenic events in the promoter and coding regions of genes, i.e. only eight indels and six single nucleotide variants. One of these indels led to a frame-shift in the Zn2Cys6 transcription factor XYR1, the general regulator of cellulase and xylanase expression, and resulted in its C-terminal truncation by 140 amino acids. Retransformation of strain QM9136 with the wild-type xyr1 allele fully recovered the ability to produce cellulases, and is thus the reason for the cellulase-negative phenotype. Introduction of an engineered xyr1 allele containing the truncating point mutation into the moderate producer T. reesei QM9414 rendered this strain also cellulase-negative. The correspondingly truncated XYR1 protein was still able to enter the nucleus, but failed to be expressed over the basal constitutive level. Conclusion: The missing 140 C-terminal amino acids of XYR1 are therefore responsible for its previously observed auto-regulation which is essential for cellulases to be expressed. Our data present a working example of the use of genome sequencing leading to a functional explanation of the QM9136 cellulase-negative phenotype.

  7. Nucleic acid arrays and methods of synthesis

    DOE Patents [OSTI]

    Sabanayagam, Chandran R. (Allston, MA); Sano, Takeshi (Needham, MA); Misasi, John (Syracuse, NY); Hatch, Anson (Seattle, WA); Cantor, Charles (Del Mar, CA)

    2001-01-01

    The present invention generally relates to high density nucleic acid arrays and methods of synthesizing nucleic acid sequences on a solid surface. Specifically, the present invention contemplates the use of stabilized nucleic acid primer sequences immobilized on solid surfaces, and circular nucleic acid sequence templates combined with the use of isothermal rolling circle amplification to thereby increase nucleic acid sequence concentrations in a sample or on an array of nucleic acid sequences.

  8. Mining fatty acids from algae

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Mining fatty acids from algae Mining fatty acids from algae Scientists at Los Alamos National Laboratory and the University of Washington are exploring the use of lipids for energy: as a starting material for creating biofuels. February 24, 2016 Chrysochromulina tobin cell structure. (A) Scanning electron micrograph of C. tobin. Two flagella are visible (marked F) along with the prominent coiled haptonema (white arrow). Scale bar represents 2.5 microns. (B) Electron micrograph of whole cell:

  9. In vivo incorporation of unnatural amino acids

    DOE Patents [OSTI]

    Schultz, Peter (La Jolla, CA); Wang, Lei (San Diego, CA); Anderson, John Christopher (San Diego, CA); Chin, Jason W. (Cambridge, GB); Liu, David R. (Lexington, MA); Magliery, Thomas J. (North Haven, CT); Meggers, Eric (Philadelphia, PA); Mehl, Ryan Aaron (Lancaster, PA); Pastrnak, Miro (San Diego, CA); Santoro, Stephen William (Cambridge, MA); Zhang, Zhiwen (San Diego, CA)

    2011-03-29

    The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids.

  10. In vivo incorporation of unnatural amino acids

    DOE Patents [OSTI]

    Schultz, Peter G. (La Jolla, CA); Wang, Lei (San Diego, CA); Anderson, John Christopher (San Diego, CA); Chin, Jason W. (Cambridge, GB); Liu, David R. (Lexington, MA); Magliery, Thomas J. (North Haven, CT); Meggers, Eric L. (Philadelphia, PA); Mehl, Ryan Aaron (Lancaster, PA); Pastrnak, Miro (San Diego, CA); Santoro, Stephen William (Cambridge, MA); Zhang, Zhiwen (San Diego, CA)

    2011-10-04

    The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids.

  11. In vivo incorporation of unnatural amino acids

    DOE Patents [OSTI]

    Schultz, Peter G. (La Jolla, CA); Wang, Lei (San Diego, CA); Anderson, John Christopher (San Diego, CA); Chin, Jason W. (Cambridge, GB); Liu, David R. (Lexington, MA); Magliery, Thomas J. (North Haven, CT); Meggers, Eric L. (Philadelphia, PA); Mehl, Ryan Aaron (Lancaster, PA); Pastrnak, Miro (San Diego, CA); Santoro, Stephen William (Cambridge, MA); Zhang, Zhiwen (San Diego, CA)

    2012-02-14

    The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids.

  12. In vivo incorporation of unnatural amino acids

    DOE Patents [OSTI]

    Schultz, Peter G. (La Jolla, CA); Wang, Lei (San Diego, CA); Anderson, John Christopher (San Diego, CA); Chin, Jason W. (Cambridge, GB); Liu, David R. (Lexington, MA); Magliery, Thomas J. (North Haven, CT); Meggers, Eric L. (Philadelphia, PA); Mehl, Ryan Aaron (Lancaster, PA); Pastrnak, Miro (San Diego, CA); Santoro, Stephen William (Cambridge, MA); Zhang, Zhiwen (San Diego, CA)

    2012-05-08

    The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids.

  13. Acid soluble, pepsin resistant platelet aggregating material

    DOE Patents [OSTI]

    Schneider, Morris D. (Knoxville, TN)

    1982-08-31

    Acid soluble, pepsin resistant, platelet aggregating material isolated from equine arterial tissue by extraction with dilute aqueous acid, method of isolation and use to control bleeding.

  14. In vivo incorporation of unnatural amino acids

    DOE Patents [OSTI]

    Schultz, Peter (La Jolla, CA); Wang, Lei (San Diego, CA); Anderson, John Christopher (San Diego, CA); Chin, Jason W. (Cambridge, GB); Liu, David R. (Lexington, MA); Magliery, Thomas J. (North Haven, CT); Meggers, Eric (Philadelphia, PA); Mehl, Ryan Aaron (Lancaster, PA); Pastrnak, Miro (San Diego, CA); Santoro, Steven William (Cambridge, MA); Zhang, Zhiwen (San Diego, CA)

    2008-05-06

    The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids.

  15. In vivo incorporation of unnatural amino acids

    DOE Patents [OSTI]

    Schultz, Peter (La Jolla, CA); Wang, Lei (San Diego, CA); Anderson, John Christopher (San Diego, CA); Chin, Jason W. (Cambridge, GB); Liu, David R. (Lexington, MA); Magliery, Thomas J. (North Haven, CT); Meggers, Eric (Philadelphia, PA); Mehl, Ryan Aaron (Lancaster, PA); Pastrnak, Miro (San Diego, CA)

    2009-12-29

    The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids

  16. In vivo incorporation of unnatural amino acids

    DOE Patents [OSTI]

    Schultz, Peter; Wang, Lei; Anderson, John Christopher; Chin, Jason William; Liu, David R.; Magliery, Thomas J.; Meggers, Eric L.; Mehl, Ryan A.; Pastrnak, Miro; Santoro, Steven William; Zhang, Zhiwen

    2006-05-16

    The invention provides methods and compositions for in vivo incorporation of unnatural amino acids. Also provided are compositions including proteins with unnatural amino acids.

  17. Photodissociation dynamics of hydroxybenzoic acids

    SciTech Connect (OSTI)

    Yang Yilin; Dyakov, Yuri; Lee, Y. T.; Ni, Chi-Kung; Sun Yilun; Hu Weiping

    2011-01-21

    Aromatic amino acids have large UV absorption cross-sections and low fluorescence quantum yields. Ultrafast internal conversion, which transforms electronic excitation energy to vibrational energy, was assumed to account for the photostability of amino acids. Recent theoretical and experimental investigations suggested that low fluorescence quantum yields of phenol (chromophore of tyrosine) are due to the dissociation from a repulsive excited state. Radicals generated from dissociation may undergo undesired reactions. It contradicts the observed photostability of amino acids. In this work, we explored the photodissociation dynamics of the tyrosine chromophores, 2-, 3- and 4-hydroxybenzoic acid in a molecular beam at 193 nm using multimass ion imaging techniques. We demonstrated that dissociation from the excited state is effectively quenched for the conformers of hydroxybenzoic acids with intramolecular hydrogen bonding. Ab initio calculations show that the excited state and the ground state potential energy surfaces change significantly for the conformers with intramolecular hydrogen bonding. It shows the importance of intramolecular hydrogen bond in the excited state dynamics and provides an alternative molecular mechanism for the photostability of aromatic amino acids upon irradiation of ultraviolet photons.

  18. HUD lead-based-paint abatement demonstration (FHA)

    SciTech Connect (OSTI)

    Not Available

    1991-08-01

    The toxic effects of lead on human beings, and particularly on young children, have been known for many years. Amendments to the Lead-Based Paint Poisoning Prevention Act (LPPPA) in 1987 and 1988 required the U.S. Department of Housing and Urban Development (HUD) to undertake a lead-based paint abatement demonstration program. The overall objective of the demonstration was to 'utilize a sufficient number of abatement methods in a sufficient number of areas and circumstances to demonstrate their relative cost-effectiveness...' One component of the demonstration was conducted in HUD-owned, vacant, single-family properties and was completed in the fall of 1990. A public housing component is expected to be completed in 1991. The report describes the objectives, research design, experience and findings of the completed component, which is generally known as the FHA demonstration, named after the Federal Housing Administration, which held title to the houses.

  19. Large-scale production of anhydrous nitric acid and nitric acid solutions of dinitrogen pentoxide

    DOE Patents [OSTI]

    Harrar, Jackson E. (Castro Valley, CA); Quong, Roland (Oakland, CA); Rigdon, Lester P. (Livermore, CA); McGuire, Raymond R. (Brentwood, CA)

    2001-01-01

    A method and apparatus are disclosed for a large scale, electrochemical production of anhydrous nitric acid and N.sub.2 O.sub.5. The method includes oxidizing a solution of N.sub.2 O.sub.4 /aqueous-HNO.sub.3 at the anode, while reducing aqueous HNO.sub.3 at the cathode, in a flow electrolyzer constructed of special materials. N.sub.2 O.sub.4 is produced at the cathode and may be separated and recycled as a feedstock for use in the anolyte. The process is controlled by regulating the electrolysis current until the desired products are obtained. The chemical compositions of the anolyte and catholyte are monitored by measurement of the solution density and the concentrations of N.sub.2 O.sub.4.

  20. Chapter 2 of the Wyoming Public Service Commission Regulations...

    Open Energy Info (EERE)

    2 of the Wyoming Public Service Commission Regulations: General Regulations Jump to: navigation, search OpenEI Reference LibraryAdd to library Legal Document- RegulationRegulation:...

  1. Recent advances in yeast molecular biology: recombinant DNA. [Lead abstract

    SciTech Connect (OSTI)

    Not Available

    1982-09-01

    Separate abstracts were prepared for the 25 papers presented at a workshop focusing on chromosomal structure, gene regulation, recombination, DNA repair, and cell type control, that have been obtained by experimental approaches incorporating the new technologies of yeast DNA transformation, molecular cloning, and DNA sequence analysis. (KRM)

  2. Methods for measuring lead concentrations in paint films

    SciTech Connect (OSTI)

    McKnight, M.E.; Byrd, W.E.; Roberts, W.E.; Lagergren, E.S.

    1989-12-01

    Recent legislation required the U.S. Department of Housing and Urban Development (HUD) to establish procedures to abate lead-based paint in existing HUD-assisted housing. The legislation also required HUD to assess the accuracy, precision, reliability, and safety of methods for measuring lead content of paint films and to investigate the availability of testers and samplers. The National Institute of Standards and Technology was requested to carry out the assessment. With regard to accuracy and precision of field measurements, it was concluded that: chemical spot tests when carried out by an experienced analytical chemistry technician can detect the presence of lead in paint films having concentrations in excess of 1 mg/sq cm about 90% of the time; the estimate of the precision of a field measurement procedure using lead-specific portable X-ray fluorescence (XRF) analyzers for lead concentrations near 1 mg/sq cm is + or - 0.6 mg/sq cm and the estimate of the bias is 0.2 mg/sq cm; this results in a 95% confidence interval of + or - 1.4 mg/sq cm; and based upon very preliminary measurements using the latest version of the spectrum analyzer portable XRF, the 95% confidence interval for field measurements is estimated to be + or - 0.5 mg/sq cm. In addition to field methods, standard laboratory procedures can be used to measure the lead content of paint samples to within a few percent of the quantity present over a wide range extending from less than 0.1 to over 10 mg/sq cm. Sample collection and sample dissolution procedures were also investigated.

  3. Leading the Way in Energy Best Practices | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Leading the Way in Energy Best Practices Leading the Way in Energy Best Practices November 13, 2013 - 12:00am Addthis By Timothy Unruh, FEMP program manager America is a world leader when it comes to tackling the energy challenges of tomorrow. As such, the federal government must set an example for the rest of the country to follow as we move toward cleaner, more efficient forms of energy. Every year, the Energy Department's Federal Energy Management Program (FEMP) honors leaders in the federal

  4. Comparison of leading parallel NAS file systems on commodity hardware

    SciTech Connect (OSTI)

    Hedges, R; Fitzgerald, K; Gary, M; Stearman, D M

    2010-11-08

    High performance computing has experienced tremendous gains in system performance over the past 20 years. Unfortunately other system capabilities, such as file I/O, have not grown commensurately. In this activity, we present the results of our tests of two leading file systems (GPFS and Lustre) on the same physical hardware. This hardware is the standard commodity storage solution in use at LLNL and, while much smaller in size, is intended to enable us to learn about differences between the two systems in terms of performance, ease of use and resilience. This work represents the first hardware consistent study of the two leading file systems that the authors are aware of.

  5. Secretary Moniz Leads DOE Town Hall | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Leads DOE Town Hall Secretary Moniz Leads DOE Town Hall May 22, 2013 - 6:30pm Addthis Secretary Moniz and Deputy Secretary Poneman address questions from Department of Energy employees in a town hall. Erin R. Pierce Erin R. Pierce Former Digital Communications Specialist, Office of Public Affairs Secretary Moniz: Week One Watch the swearing-in ceremony. See a video recap of Secretary Moniz's first day in office. View a slideshow of photos from the DOE Town Hall. "I have a lot of hope and

  6. Research Leads to Improved Fuel Yields from Smaller Antenna Algae |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Research Leads to Improved Fuel Yields from Smaller Antenna Algae Research Leads to Improved Fuel Yields from Smaller Antenna Algae May 13, 2014 - 12:06pm Addthis Tasios Melis (center) shows plates with tla3 algae and its parent strain to Katie Randolph (left) and Sunita Satyapal during a site visit to his lab at the University of California, Berkeley. Tasios Melis (center) shows plates with tla3 algae and its parent strain to Katie Randolph (left) and Sunita Satyapal

  7. Hanford Employee Returns to Finish Glovebox Cleanup as Team Lead |

    Energy Savers [EERE]

    Department of Energy Employee Returns to Finish Glovebox Cleanup as Team Lead Hanford Employee Returns to Finish Glovebox Cleanup as Team Lead March 16, 2016 - 12:20pm Addthis Hix, right, discusses a work assignment with a team member. Hix, right, discusses a work assignment with a team member. The crew that cut up and removed the two most hazardous gloveboxes in PFP. The crew that cut up and removed the two most hazardous gloveboxes in PFP. Due to the airborne radiological contamination

  8. Discovery of Weyl Semimetals May Lead to Novel Future Spintronic

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Applications Discovery of Weyl Semimetals May Lead to Novel Future Spintronic Applications Discovery of Weyl Semimetals May Lead to Novel Future Spintronic Applications Print Wednesday, 09 December 2015 00:00 A long-sought exotic particle from the realm of high-energy physics, the Weyl fermion, has recently been discovered in solids. 
Because these Weyl fermions do not bear mass, they behave like photons and can travel unusually fast and with little resistance. A team of researchers using

  9. GE leads the way in photonics research | GE Global Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GE continues leading role in photonics industry - from LED to digital x-ray Click to email this to a friend (Opens in new window) Share on Facebook (Opens in new window) Click to share (Opens in new window) Click to share on LinkedIn (Opens in new window) Click to share on Tumblr (Opens in new window) GE continues leading role in photonics industry - from LED to digital x-ray Danielle Merfeld, Ph.D. 2015.07.27 Vice President Joseph Biden joined New York Gov. Andrew Cuomo in Rochester, New York

  10. National Labs Leading Charge on Building Better Batteries | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Labs Leading Charge on Building Better Batteries National Labs Leading Charge on Building Better Batteries September 26, 2011 - 12:36pm Addthis Berkeley Lab researchers have designed a new anode -- a key component of lithium ion batteries -- made from a "tailored polymer" (pictured above at right in purple). It has a greater capacity to store energy since it can conduct electricity itself rather than using a polymer binder (such as PVDF, pictured above at left in brown) in

  11. Leading the Way in Energy Best Practices | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Leading the Way in Energy Best Practices Leading the Way in Energy Best Practices November 6, 2013 - 5:32pm Addthis Fort Carson’s first U.S. Green Building Council platinum-level Leadership in Energy and Environmental Design certified facility, the 4th Armored Brigade Combat Team Brigade and Battalion Headquarters, features a 482 kilowatt ground-mounted, tracking photovoltaic system. | U.S. Army photo Fort Carson's first U.S. Green Building Council platinum-level Leadership in Energy and

  12. Cool Roofs Lead to Cooler Cities | Department of Energy

    Office of Environmental Management (EM)

    Roofs Lead to Cooler Cities Cool Roofs Lead to Cooler Cities July 23, 2010 - 2:07pm Addthis John Schueler John Schueler Former New Media Specialist, Office of Public Affairs How does it work? Dark-colored roofs and roadways create what is called the "urban heat island effect," meaning a city is significantly warmer than its surrounding rural areas. Light colored roofs reduce the heat island effect and improve air quality by reducing emissions. Lighter-colored roofing surfaces reflect

  13. Natural Gas Regulation | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Natural Gas Regulation Natural Gas Regulation Natural Gas Regulation The Natural Gas Act of 1938, as amended, requires any person who wishes to import and/or export natural gas, (including liquefied natural gas, compressed natural gas, compressed gas liquids, etc.) from or to a foreign country must first obtain an authorization from the Department of Energy. The authorizations are granted by the Office of Regulation and International Engagement, Division of Natural Gas Regulation. DOE grants two

  14. Allowance trading activity and state regulatory rulings: Evidence from the US Acid Rain Program

    SciTech Connect (OSTI)

    Bailey, E.M.

    1997-12-31

    The US Acid Rain Program is one of the first, and by far the most extensive, applications of a market based approach to pollution control. From the beginning, there has been concern whether utilities would participate in allowance trading, and whether regulatory activity at the state level would further complicate utilities` decision to trade allowances. This paper finds that public utility commission regulation has encouraged allowance trading activity in states with regulatory rulings, but that allowance trading activity has not been limited to states issuing regulations. Until there is evidence suggesting that significant additional cost savings could have been obtained if additional allowance trading activity had occurred in states without regulations or that utilities in states with regulations are still not taking advantage of all cost saving trading opportunities, this analysis suggests that there is little reason to believe that allowance trading activity is impeded by public utility commission regulations.

  15. DOE Leads National Research Program in Gas Hydrates

    Broader source: Energy.gov [DOE]

    The U.S. Department of Energy today told Congress the agency is leading a nationwide program in search of naturally occurring natural gas hydrates - a potentially significant storehouse of methane--with far reaching implications for the environment and the nation's future energy supplies.

  16. Huizenga leads safety of spent fuel management, radioactive waste

    National Nuclear Security Administration (NNSA)

    management meeting in Vienna | National Nuclear Security Administration Huizenga leads safety of spent fuel management, radioactive waste management meeting in Vienna | National Nuclear Security Administration Facebook Twitter Youtube Flickr RSS People Mission Managing the Stockpile Preventing Proliferation Powering the Nuclear Navy Emergency Response Recapitalizing Our Infrastructure Countering Nuclear Terrorism About Our Programs Our History Who We Are Our Leadership Our Locations Budget

  17. Materials Physics and Applications Division Lead | National Nuclear

    National Nuclear Security Administration (NNSA)

    Security Administration Physics and Applications Division Lead | National Nuclear Security Administration Facebook Twitter Youtube Flickr RSS People Mission Managing the Stockpile Preventing Proliferation Powering the Nuclear Navy Emergency Response Recapitalizing Our Infrastructure Countering Nuclear Terrorism About Our Programs Our History Who We Are Our Leadership Our Locations Budget Our Operations Library Bios Congressional Testimony Fact Sheets Newsletters Press Releases Photo Gallery

  18. Zarb Appointed to Lead the Federal Energy Administration | National Nuclear

    National Nuclear Security Administration (NNSA)

    Security Administration Zarb Appointed to Lead the Federal Energy Administration | National Nuclear Security Administration Facebook Twitter Youtube Flickr RSS People Mission Managing the Stockpile Preventing Proliferation Powering the Nuclear Navy Emergency Response Recapitalizing Our Infrastructure Countering Nuclear Terrorism About Our Programs Our History Who We Are Our Leadership Our Locations Budget Our Operations Library Bios Congressional Testimony Fact Sheets Newsletters Press

  19. Frequency regulator for synchronous generators

    DOE Patents [OSTI]

    Karlicek, R.F.

    1982-08-10

    The present invention is directed to a novel frequency regulator which controls a generator output frequency for variations in both the input power to the generator and the power supplied to an uncontrolled external load. The present invention further includes over current and current balance protection devices which are relatively inexpensive to manufacture, which may be encapsulated to provide protection from the operating environment and which respond more quickly than previously known electromechanical devices. 11 figs.

  20. Frequency regulator for synchronous generators

    DOE Patents [OSTI]

    Karlicek, Robert F. (1920 Camino Centroloma, Fullerton, CA 92633)

    1982-01-01

    The present invention is directed to a novel frequency regulator which controls a generator output frequency for variations in both the input power to the generator and the power supplied to an uncontrolled external load. The present invention further includes over current and current balance protection devices which are relatively inexpensive to manufacture, which may be encapsulated to provide protection from the operating environment and which respond more quickly than previously known electromechanical devices.

  1. GP-8 LAWS AND REGULATIONS

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    40-DOP (5-2011) Supersedes (7-2010) issue DECLARATION of OCCUPATIONAL MEDICINE PROVIDER GENERAL INFORMATION PURPOSE All Contractors and their lower-tier subcontractors must comply with the Department of Energy's Worker Safety and Health Program regulation, 10 CFR 851, "Worker Safety and Health Program (WSHP). The WSHP enforces worker safety and health requirements including, but not limited to, standards of the Occupational Safety and Health Administration (OSHA), American National

  2. Improving Regulation and Regulatory Review

    Office of Environmental Management (EM)

    Alton Strategic Environmental Group New Port Richey, FL charles.alton@earthlink.net April 4, 2011 Daniel Cohen, Assistant General Counsel Legislation, Regulation, and Energy Efficiency Office of the General Counsel U.S. Department of Energy 1000 Independence Avenue, SW Washington, DC 20585 Dear Mr. Cohen: I have reviewed the Request For Information regarding Reducing Regulatory Reform issued February 3, 2011 (Federal Register /Vol. 76, No. 23 /Thursday, February 3, 2011 /Notices). In the

  3. Evaluation of potential mixed wastes containing lead, chromium, or used oil

    SciTech Connect (OSTI)

    Siskind, B.; MacKenzie, D.R.; Bowerman, B.S.; Kempf, C.R.; Piciulo, P.L.

    1987-01-01

    This paper presents the results of follow-on studies conducted by Brookhaven National Laboratory (BNL) for the Nuclear Regulatory Commission (NRC) on certain kinds of low-level waste (LLW) which could also be classified as hazardous waste subject to regulation by the Environmental Protection Agency (EPA). Such LLW is termed ''mixed waste.'' Additional data have been collected and evaluated on two categories of potential mixed waste, namely LLW containing metallic lead and LLW containing chromium. Additionally, LLW with organic liquids, especially liquid scintillation wastes, are reviewed. In light of a proposed EPA rule to list used oil as hazardous waste, the potential mixed waste hazard of used oil contaminated with radionuclides is discussed. It is concluded that the EPA test for determining whether a solid waste exhibits the hazardous characteristic of extraction procedure toxicity does not adequately simulate the burial environment at LLW disposal sites, and in particular, does not adequately assess the potential for dissolution and transport of buried metallic lead. Also, although chromates are, in general, not a normal or routine constitutent in commercial LLW (with the possible exception of chemical decontamination wastes), light water reactors which do use chromates might find it beneficial to consider alternative corrosion inhibitors. In addition, it is noted that if used oil is listed by the EPA as hazardous waste, LLW oil may be managed by a scheme including one or more of the following processes: incineration, immobilization, sorption, aqueous extraction and glass furnace processing.

  4. A blasting additive that renders wastes non hazardous in lead paint abatement projects

    SciTech Connect (OSTI)

    Clark, R.; Rapp, D.J.; McGrew, M.

    1994-12-31

    Maintenance of steel structures often produces abrasive wastes that are considered toxic and hazardous due to the lead content of the old paint system present in spent abrasives. Environmental regulations in the US and Canada effectively preclude on-site treatment and disposal of these wastes, thereby forcing them into costly transport and secure disposal options. The authors have developed an abrasive additive that allows dry or wet blasting to remove old paint systems, but the resultant wastes are considered non-hazardous and are eligible for recycling or non-hazardous waste disposal, both at sharply reduced costs. The agent does not ``mask`` environmental test results, but does produce a stable residue suitable for long term disposal or reuse. Surface conditions after application of abrasives appear to be amenable to virtually all paint systems tested. The process is in use on an estimated 10% of all steel based lead paint abatement projects in the US, and is experiencing considerable growth in market acceptance. The technology may allow disposal cost reductions in excess of 50%.

  5. NRC - regulator of nuclear safety

    SciTech Connect (OSTI)

    1997-05-01

    The U.S. Nuclear Regulatory Commission (NRC) was formed in 1975 to regulate the various commercial and institutional uses of nuclear energy, including nuclear power plants. The agency succeeded the Atomic Energy Commission, which previously had responsibility for both developing and regulating nuclear activities. Federal research and development work for all energy sources, as well as nuclear weapons production, is now conducted by the U.S. Department of Energy. Under its responsibility to protect public health and safety, the NRC has three principal regulatory functions: (1) establish standards and regulations, (2) issue licenses for nuclear facilities and users of nuclear materials, and (3) inspect facilities and users of nuclear materials to ensure compliance with the requirements. These regulatory functions relate to both nuclear power plants and to other uses of nuclear materials - like nuclear medicine programs at hospitals, academic activities at educational institutions, research work, and such industrial applications as gauges and testing equipment. The NRC places a high priority on keeping the public informed of its work. The agency recognizes the interest of citizens in what it does through such activities as maintaining public document rooms across the country and holding public hearings, public meetings in local areas, and discussions with individuals and organizations.

  6. Acid sorption regeneration process using carbon dioxide

    DOE Patents [OSTI]

    King, C. Judson (Kensington, CA); Husson, Scott M. (Anderson, SC)

    2001-01-01

    Carboxylic acids are sorbed from aqueous feedstocks onto a solid adsorbent in the presence of carbon dioxide under pressure. The acids are freed from the sorbent phase by a suitable regeneration method, one of which is treating them with an organic alkylamine solution thus forming an alkylamine-carboxylic acid complex which thermally decomposes to the desired carboxylic acid and the alkylamine.

  7. High speed nucleic acid sequencing

    DOE Patents [OSTI]

    Korlach, Jonas (Ithaca, NY); Webb, Watt W. (Ithaca, NY); Levene, Michael (Ithaca, NY); Turner, Stephen (Ithaca, NY); Craighead, Harold G. (Ithaca, NY); Foquet, Mathieu (Ithaca, NY)

    2011-05-17

    The present invention is directed to a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the polymerization reaction is measured on a molecule of nucleic acid. Each type of labeled nucleotide comprises an acceptor fluorophore attached to a phosphate portion of the nucleotide such that the fluorophore is removed upon incorporation into a growing strand. Fluorescent signal is emitted via fluorescent resonance energy transfer between the donor fluorophore and the acceptor fluorophore as each nucleotide is incorporated into the growing strand. The sequence is deduced by identifying which base is being incorporated into the growing strand.

  8. Identifying a base in a nucleic acid

    DOE Patents [OSTI]

    Fodor, Stephen P. A.; Lipshutz, Robert J.; Huang, Xiaohua

    2005-02-08

    Devices and techniques for hybridization of nucleic acids and for determining the sequence of nucleic acids. Arrays of nucleic acids are formed by techniques, preferably high resolution, light-directed techniques. Positions of hybridization of a target nucleic acid are determined by, e.g., epifluorescence microscopy. Devices and techniques are proposed to determine the sequence of a target nucleic acid more efficiently and more quickly through such synthesis and detection techniques.

  9. Lead and cadmium concentrations in livestock bred in Campania, Italy

    SciTech Connect (OSTI)

    Amodio-Cocchieri, R.; Fiore, P.

    1987-09-01

    Among the various aspects of environmental pollution, special attention must be directed to heavy metals, which show a remarkable tendency to accumulate in tissues and organs of animals and humans. Particularly, lead and cadmium are of great concern when one considers that the variety of their uses has increased their level in the environment and that they have been identified as the causes of several clinical problems. Since heavy metals may be used as indicators of industrial contamination, the Italian Ministry of Health started a research program concerning the lead and cadmium levels in meat, cow's milk and eggs produce by Italian livestock and in well water, and in local and industrial feeds tuffs employed in their breeding. This is the object of the present study carried out in the Campania province.

  10. Next-to-leading order predictions for WW + jet production

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Campbell, John M.; Miller, David J.; Robens, Tania

    2015-07-28

    In this study we report on a next-to-leading order calculation of WW + jet production at hadron colliders, with subsequent leptonic decays of the W bosons included. The calculation of the one-loop contributions is performed using generalized unitarity methods in order to derive analytic expressions for the relevant amplitudes. These amplitudes have been implemented in the parton-level Monte Carlo generator mcfm, which we use to provide a complete next-to-leading order calculation. Predictions for total cross sections, as well as differential distributions for several key observables, are computed both for the LHC operating at 14 TeV as well as for amore » possible future 100 TeV proton-proton collider.« less

  11. An alternative to removing lead-based paint: Overcoating

    SciTech Connect (OSTI)

    Vernon, L.S.

    1996-02-01

    The case of repairing a municipal water tank coated with lead-based paint (LBP) is used to illustrate some of the benefits of overcoating, a possible alternative to removing failing paint. The paper discusses data regarding performance of the waterborne acrylic used in the case study, briefly reviews revisions to specifications for the coating`s use, and offers some costs by which to compare use of a waterborne encapsulant such as that used in the case study with either removal and recoating or use of a solvent-borne encapsulant. A surface-tolerant, water-based, corrosion-resistant acrylic was selected to overcoat the LBP. By cleaning and overcoating the existing adherent LBP using the acrylic coating, chances of lead exposure to workers and the public were reduced. Eliminating abrasive blasting and the need for full containment saved about $80,000 to $100,000.

  12. Method for production of petroselinic acid and OMEGA12 hexadecanoic acid in transgenic plants

    DOE Patents [OSTI]

    Ohlrogge, J.B.; Cahoon, E.B.; Shanklin, J.; Somerville, C.R.

    1995-07-04

    The present invention relates to a process for producing lipids containing the fatty acid, petroselinic acid, in plants. The production of petroselinic acid is accomplished by genetically transforming plants which do not normally accumulate petroselinic acid with a gene for a {omega}12 desaturase from another species which does normally accumulate petroselinic acid. 19 figs.

  13. Method of increasing conversion of a fatty acid to its corresponding dicarboxylic acid

    DOE Patents [OSTI]

    Craft, David L.; Wilson, C. Ron; Eirich, Dudley; Zhang, Yeyan

    2004-09-14

    A nucleic acid sequence including a CYP promoter operably linked to nucleic acid encoding a heterologous protein is provided to increase transcription of the nucleic acid. Expression vectors and host cells containing the nucleic acid sequence are also provided. The methods and compositions described herein are especially useful in the production of polycarboxylic acids by yeast cells.

  14. Method for production of petroselinic acid and OMEGA12 hexadecanoic acid in transgenic plants

    DOE Patents [OSTI]

    Ohlrogge, John B. (Okemos, MI); Cahoon, Edgar B. (Lansing, MI); Shanklin, John (Upton, NY); Somerville, Christopher R. (Okemos, MI)

    1995-01-01

    The present invention relates to a process for producing lipids containing the fatty acid petroselinic acid in plants. The production of petroselinic acid is accomplished by genetically transforming plants which do not normally accumulate petroselinic acid with a gene for a .omega.12 desaturase from another species which does normally accumulate petroselinic acid.

  15. Ames Laboratory to lead new consortium to advance refrigeration technology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    | The Ames Laboratory Laboratory to lead new consortium to advance refrigeration technology Ames Laboratory will be the home of a new research consortium for the discovery and development of more environmentally friendly and energy-efficient refrigeration technologies, sponsored by DOE's Office of Energy Efficiency and Renewable Energy (EERE). The consortium, named CaloriCoolTM, will pursue the development of alternative forms of refrigeration technologies, called caloric cooling, in

  16. Pennington To Lead Jefferson Lab Theory Center | Jefferson Lab

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Pennington To Lead Jefferson Lab Theory Center dph0mrp.jpg NEWPORT NEWS, VA - After an extensive international search, the U.S. Department of Energy's Thomas Jefferson National Accelerator Facility has selected Michael R. Pennington, an internationally known physicist, as Associate Director for Theoretical and Computational Physics. Pennington is currently a Professor of Mathematical Sciences & Physics and Dean for Educational Outreach at the Durham University in England. Since 2007,

  17. Nicholas J. Wright! Advanced Technologies Group Lead NERSC Initiative:

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Nicholas J. Wright! Advanced Technologies Group Lead NERSC Initiative: Preparing Applications for Exascale --- 1 --- NERSC U ser G roup M ee0ng February 1 2. 2 013 * Technology disruption is underway at the processor and memory level. Computing challenges include: - Energy efficiency - Concurrency - Data movement - Programmability - Resilience * We can only meet these challenges through both hardware and software innovation - Rewrite application codes - Try to influence computer industry 2

  18. Non-lead environmentally safe projectiles and explosive container

    DOE Patents [OSTI]

    Lowden, R.A.; McCoig, T.M.; Dooley, J.B.; Smith, C.M.

    1999-06-15

    A solid object having controlled frangibility, such as a bullet or a container for explosives, is made by combining two different metals in proportions calculated to achieve a desired density, without using lead. A wetting material is deposited on the base constituent which is made of a relative dense, hard material. The wetting material enhances the wettability of the base constituent with the binder constituent, which is lighter and softer than the base constituent. 10 figs.

  19. New Director to lead Technology Development and Commercialization division

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    | Argonne National Laboratory New Director to lead Technology Development and Commercialization division April 2, 2015 Tweet EmailPrint Suresh Sunderrajan has been appointed Director of Argonne's Technology Development and Commercialization Division (TDC), effective April 20. Sunderrajan comes to Argonne from United Technologies Corporation, where he served as Director of Innovation Business Development (IBD), the Corporate IP monetization organization. He was responsible for patent and

  20. Greg Wilson to Lead National Center for Photovoltaics - News Releases |

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NREL Greg Wilson to Lead National Center for Photovoltaics November 11, 2011 Photo of Dr. Gregory M. Wilson Dr. Gregory M. Wilson has been named director of the National Center for Photovoltaics at NREL. Dr. Gregory M. Wilson has been named director of the National Center for Photovoltaics (NCPV) at the U.S. Department of Energy's (DOE) National Renewable Energy Laboratory (NREL), effective Nov. 28. Wilson brings 17 years of experience in silicon research and in photovoltaic leadership to

  1. Method of making a non-lead hollow point bullet

    DOE Patents [OSTI]

    Vaughn, Norman L.; Lowden, Richard A.

    2003-10-07

    The method of making a non-lead hollow point bullet has the steps of a) compressing an unsintered powdered metal composite core into a jacket, b) punching a hollow cavity tip portion into the core, c) seating an insert, the insert having a hollow point tip and a tail protrusion, on top of the core such that the tail protrusion couples with the hollow cavity tip portion, and d) swaging the open tip of the jacket.

  2. Non-lead, environmentally safe projectiles and explosives containers

    DOE Patents [OSTI]

    Lowden, Richard A. (Clinton, TN); McCoig, Thomas M. (Maryville, TN); Dooley, Joseph B. (Kingston, TN); Smith, Cyrus M. (Knoxville, TN)

    2001-01-16

    A solid object having controlled frangibility, such as a bullet or a container for explosives, is made by combining two different metals in proportions calculated to achieve a desired density, without using lead. A wetting material is deposited on the base constituent which is made of a relative dense, hard material. The wetting material enhances the wettability of the base constituent with the binder constituent, which is lighter and softer than the base constituent.

  3. Non-lead environmentally safe projectiles and explosive container

    DOE Patents [OSTI]

    Lowden, Richard A. (Clinton, TN); McCoig, Thomas M. (Maryville, TN); Dooley, Joseph B. (Kingston, TN); Smith, Cyrus M. (Knoxville, TN)

    1999-06-15

    A solid object having controlled frangibility, such as a bullet or a container for explosives, is made by combining two different metals in proportions calculated to achieve a desired density, without using lead. A wetting material is deposited on the base constituent which is made of a relative dense, hard material. The wetting material enhances the wettability of the base constituent with the binder constituent, which is lighter and softer than the base constituent.

  4. Leading the Charge: Akwesasne Housing Authority Director Retha Herne |

    Energy Savers [EERE]

    Department of Energy Akwesasne Housing Authority Director Retha Herne Leading the Charge: Akwesasne Housing Authority Director Retha Herne October 28, 2015 - 9:02am Addthis Energy-efficient homes in AHA’s Sunrise Acres Complex include such features as rooftop solar domestic hot water. Photo from Akwesasne Housing Authority. Energy-efficient homes in AHA's Sunrise Acres Complex include such features as rooftop solar domestic hot water. Photo from Akwesasne Housing Authority. Solar panels

  5. Director Arvizu Named Leading Hispanic in Science and Technology - News

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Releases | NREL Director Arvizu Named Leading Hispanic in Science and Technology Organization Promoting Technology Careers Awards Arvizu Highest Honor October 13, 2008 Dan Arvizu, who has served as director of the U.S. Department of Energy's (DOE) National Renewable Energy Laboratory (NREL) since 2005, was inducted into the Hispanic Engineer National Achievement Awards Conference (HENAAC) Hall of Fame at a ceremony in Houston, Texas on Saturday. The Hall of Fame's purpose is to

  6. Expulsion Leads to a New Catalyst | The Ames Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Expulsion Leads to a New Catalyst Locating a catalyst and reactants in confined spaces makes catalytic reactions go faster in the desired direction. Of course, the reaction products have to be removed from the confined spaces and researchers have developed a new approach to expelling aqueous reaction products. This works for confinement in nanometer-sized pores in silica particles. By lining the insides of the pores with both catalysts and a fluorinated chemical, like that found in Teflon®,

  7. Alan Bishop selected to lead LANL Science, Technology & Engineering

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    directorate Science, Technology & Engineering directorate Alan Bishop selected to lead LANL Science, Technology & Engineering directorate Bishop has been acting in that role since Aug. 29, 2011. August 17, 2012 Alan Bishop Alan Bishop Contact Nancy Ambrosiano Communications Office (505) 667-0471 Email LOS ALAMOS, NEW MEXICO, August 17, 2012-Los Alamos National Laboratory Director Charles McMillan announced today that after a yearlong, nationwide search, Alan Bishop has been selected

  8. NREL Leads Energy Systems Integration - Continuum Magazine | NREL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Issue 4 Continuum. Clean Energy Innovation at NREL NREL Leads Energy Systems Integration Continuum is the National Renewable Energy Laboratory's publication that showcases the laboratory's latest and most impactful clean energy innovations and the researchers and unique facilities that make it all happen. Dan Says From our director Dan says More than a Dream-a Renewable Electricity Future 01 More than a Dream-a Renewable Electricity Future With improved grid flexibility, storage, and

  9. DOE Funding Leads to New Technology that is Revolutionizing Chemical

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    For immediate release DOE Funding Leads to New Technology that is Revolutionizing Chemical Analysis Research funded by the DOE Office of Science has led to the commercialization of a new product, the Polyarc(tm) reactor, which is improving chemical analysis for scientists using gas chromatography (GC) with flame ionization detectors (FID). (NEWARK, DE) November 9, 2015- A universal carbon detection technology discovered by researchers at the Catalysis Center for Energy Innovation (CCEI), an

  10. Eliot Feibush leads new Princeton consortium to visualize Big Data |

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Princeton Plasma Physics Lab Eliot Feibush leads new Princeton consortium to visualize Big Data By John Greenwald April 22, 2015 Tweet Widget Google Plus One Share on Facebook Eliot Feibush (Photo by Elle Starkman/PPPL Office of Communications) Eliot Feibush Gallery: Cross section of a tokamak plasma with red and blue colors showing direction and structure of plasma flow. (Photo by PPPL) Cross section of a tokamak plasma with red and blue colors showing direction and structure of plasma

  11. Novel Nanoparticle Production Method Could Lead to Better Lights, Lenses,

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Solar Cells Novel Nanoparticle Production Method Could Lead to Better Lights, Lenses, Solar Cells - Sandia Energy Energy Search Icon Sandia Home Locations Contact Us Employee Locator Energy & Climate Secure & Sustainable Energy Future Stationary Power Energy Conversion Efficiency Solar Energy Wind Energy Water Power Supercritical CO2 Geothermal Natural Gas Safety, Security & Resilience of the Energy Infrastructure Energy Storage Nuclear Power & Engineering Grid Modernization

  12. Lester to lead ORISE's scientific and technical peer review program

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Lester to lead ORISE's scientific and technical peer review program FOR IMMEDIATE RELEASE June 14, 2010 FY10-42 OAK RIDGE, Tenn.-Oak Ridge Associated Universities has appointed Tony Lester as director of the Oak Ridge Institute for Science and Education's program focused on scientific peer review. Lester has been serving in this role in an acting capacity since September 2009. Tony Lester Tony Lester In his role, Lester manages a research peer review capability that coordinates the use of

  13. NREL Leads Energy Systems Integration, Continuum Magazine: Issue 4 (Book)

    SciTech Connect (OSTI)

    Not Available

    2013-04-01

    Continuum Magazine showcases NREL's latest and most impactful clean energy innovations. This issue, 'NREL Leads Energy Systems Integration' explores the discipline of energy systems integration, in particular the role of the laboratory's new, one-of-a-kind Energy System Integration Facility. NREL scientists, engineers, and analysts deeply understand the fundamental science and technologies underpinning major energy producing and consuming systems, as well as the transmission infrastructure and communications and data networks required to integrate energy systems at all scales.

  14. Data, Feedback, & Awareness Lead to Big Energy Savings

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    energy feedback and "staff monitors" to reinforce commu- nication and activity led to improved routine practices and significant energy savings. Members of the Navy Region Southwest Metro San Diego regional energy management team with an example poster from their energy awareness program. (Photo courtesy FEMP/NRSMSD.) Data, Feedback, & Awareness Lead to Big Energy Savings The Navy Region Southwest Metro San Diego Area (NRSMSD) regional energy management team achieved signifcant

  15. Ames Laboratory will lead new consortium to research caloric materials,

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    advance refrigeration technology | The Ames Laboratory will lead new consortium to research caloric materials, advance refrigeration technology Contacts: For release: Feb. 24, 2016 Duane Johnson, Chief Research Officer, (515)-294-9649 Vitalij Pecharsky, Senior Scientist, (515)-294-8220 Laura Millsaps, Public Affairs, (515) 294-3474 The U.S. Department of Energy's Ames Laboratory will be the home of a new research consortium for the discovery and development of more environmentally friendly

  16. NNSA Computers Lead Global List | National Nuclear Security Administration

    National Nuclear Security Administration (NNSA)

    Computers Lead Global List | National Nuclear Security Administration Facebook Twitter Youtube Flickr RSS People Mission Managing the Stockpile Preventing Proliferation Powering the Nuclear Navy Emergency Response Recapitalizing Our Infrastructure Countering Nuclear Terrorism About Our Programs Our History Who We Are Our Leadership Our Locations Budget Our Operations Library Bios Congressional Testimony Fact Sheets Newsletters Press Releases Photo Gallery Jobs Apply for Our Jobs Our Jobs Working

  17. Leading the Charge: Harold Frank | Department of Energy

    Office of Environmental Management (EM)

    Harold Frank Leading the Charge: Harold Frank June 22, 2012 - 5:11pm Addthis Harold "Gus" Frank, Forest County Potawatomi Community Chairman and 2012 White House "Champion of Change". Photo from Potawatomi Traveling Times Harold "Gus" Frank, Forest County Potawatomi Community Chairman and 2012 White House "Champion of Change". Photo from Potawatomi Traveling Times Solar panels on the rooftop of the Forest County Potawatomi Tribe's administration building

  18. Leading the Charge: Jana Ganion Advances Blue Lake Rancheria's Climate

    Office of Environmental Management (EM)

    Action Agenda | Department of Energy Jana Ganion Advances Blue Lake Rancheria's Climate Action Agenda Leading the Charge: Jana Ganion Advances Blue Lake Rancheria's Climate Action Agenda February 27, 2015 - 10:38am Addthis Jana Ganion is the Energy Director for the Blue Lake Rancheria. Jana Ganion is the Energy Director for the Blue Lake Rancheria. Change doesn't happen on its own. It's led by dedicated and passionate people who are committed to empowering Indian Country to energize future

  19. Leading the Charge: Jim Manion | Department of Energy

    Office of Environmental Management (EM)

    Jim Manion Leading the Charge: Jim Manion February 23, 2012 - 5:23pm Addthis Jim Manion, Confederated Tribes of the Warm Springs Reservation of Oregon Jim Manion, Confederated Tribes of the Warm Springs Reservation of Oregon What are the greatest energy development opportunities for Indian Country? Bring power to communities within Indian Country that currently don't have energy Create needed jobs that offer tribal members opportunities to earn incomes sufficient to support their families

  20. Leading the Charge: Tribal Women in Power | Department of Energy

    Office of Environmental Management (EM)

    Tribal Women in Power Leading the Charge: Tribal Women in Power October 22, 2012 - 4:19pm Addthis Andrea Alexander, Makah Tribe in Neah Bay (Washington)/Affiliated Tribes of Northwest Indians Andrea Alexander, Makah Tribe in Neah Bay (Washington)/Affiliated Tribes of Northwest Indians Kathy Mayo, Eagle Village in Upper Yukon (Alaska)/Tanana Chiefs Conference Kathy Mayo, Eagle Village in Upper Yukon (Alaska)/Tanana Chiefs Conference Tara Hess-McGeown, Washoe Tribe of Nevada and

  1. MOX Lead Assembly Fabrication at the Savannah River Site

    SciTech Connect (OSTI)

    Geddes, R.L.; Spiker, D.L.; Poon, A.P.

    1997-12-01

    The U. S. Department of Energy (DOE) announced its intent to prepare an Environmental Impact Statement (EIS) under the National Environmental Policy Act (NEPA) on the disposition of the nations weapon-usable surplus plutonium.This EIS is tiered from the Storage and Disposition of Weapons-Usable Fissile Material Programmatic Environmental Impact Statement issued in December 1996,and the associated Record of Decision issued on January, 1997. The EIS will examine reasonable alternatives and potential environmental impacts for the proposed siting, construction, and operation of three types of facilities for plutonium disposition. The three types of facilities are: a pit disassembly and conversion facility, a facility to immobilize surplus plutonium in a glass or ceramic form for disposition, and a facility to fabricate plutonium oxide into mixed oxide (MOX) fuel.As an integral part of the surplus plutonium program, Oak Ridge National Laboratory (ORNL) was tasked by the DOE Office of Fissile Material Disposition(MD) as the technical lead to organize and evaluate existing facilities in the DOE complex which may meet MD`s need for a domestic MOX fuel fabrication demonstration facility. The Lead Assembly (LA) facility is to produce 1 MT of usable test fuel per year for three years. The Savannah River Site (SRS) as the only operating plutonium processing site in the DOE complex, proposes two options to carry out the fabrication of MOX fuel lead test assemblies: an all Category I facility option and a combined Category I and non-Category I facilities option.

  2. Leading twist nuclear shadowing phenomena in hard processes with nuclei

    SciTech Connect (OSTI)

    Leonid Frankfurt, Vadim Guzey, Mark Strikman

    2012-03-01

    We present and discuss the theory and phenomenology of the leading twist theory of nuclear shadowing which is based on the combination of the generalization of Gribov-Glauber theory, QCD factorization theorems, and HERA QCD analysis of diffraction in lepton-proton deep inelastic scattering (DIS). We apply this technique for the analysis of a wide range of hard processes with nuclei-inclusive DIS on deuterons, medium-range and heavy nuclei, coherent and incoherent diffractive DIS with nuclei, and hard diffraction in proton-nucleus scattering - and make predictions for the effect of nuclear shadowing in the corresponding sea quark and gluon parton distributions. We also analyze the role of the leading twist nuclear shadowing in generalized parton distributions in nuclei and certain characteristics of final states in nuclear DIS. We discuss the limits of applicability of the leading twist approximation for small x scattering off nuclei and the onset of the black disk regime and methods of detecting it. It will be possible to check many of our predictions in the near future in the studies of the ultraperipheral collisions at the Large Hadron Collider (LHC). Further checks will be possible in pA collisions at the LHC and forward hadron production at Relativistic Heavy Ion Collider (RHIC). Detailed tests will be possible at an Electon-Ion Collider (EIC) in USA and at the Large Hadron-Electron Collider (LHeC) at CERN.

  3. Output-Based Regulations: A Handbook for Air Regulators (U.S. EPA), August

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    2004 | Department of Energy Output-Based Regulations: A Handbook for Air Regulators (U.S. EPA), August 2004 Output-Based Regulations: A Handbook for Air Regulators (U.S. EPA), August 2004 The U.S. Environmental Protection Agency (EPA) developed this handbook to assist state, local, and tribal regulators in developing output-based regulations. The handbook provides practical information to help regulators decide if they want to use output-based regulations and explains how to develop an

  4. Colorado Code of Regulations 4 CCR 723-3, Rules Regulating Electric...

    Open Energy Info (EERE)

    Colorado Code of Regulations 4 CCR 723-3, Rules Regulating Electric Utilities Jump to: navigation, search OpenEI Reference LibraryAdd to library Legal Document-...

  5. Code of Colorado Regulations 4 CCR 723-3, Rules Regulating Electric...

    Open Energy Info (EERE)

    Code of Colorado Regulations 4 CCR 723-3, Rules Regulating Electric Utilities Jump to: navigation, search OpenEI Reference LibraryAdd to library Legal Document-...

  6. Clean Water Act and Regulations (EPA)

    Broader source: Energy.gov [DOE]

    The Clean Water Act (CWA; 33 U.S.C. §1251 et seq.) establishes the basic structure for regulating discharges of pollutants into the waters of the United States and regulating quality standards for surface waters.

  7. Process for forming sulfuric acid

    DOE Patents [OSTI]

    Lu, Wen-Tong P. (Upper St. Clair, PA)

    1981-01-01

    An improved electrode is disclosed for the anode in a sulfur cycle hydrogen generation process where sulfur dioxie is oxidized to form sulfuric acid at the anode. The active compound in the electrode is palladium, palladium oxide, an alloy of palladium, or a mixture thereof. The active compound may be deposited on a porous, stable, conductive substrate.

  8. Surface mine regulations complicate reclamation

    SciTech Connect (OSTI)

    Seltz-Patrash, A.

    1980-09-01

    The Surface Mining Control and Reclamation Act of 1977 is a landmark environmental law intended to protect U.S. lands from stripmining effects. However, coal mine operators claim that some SMCRA regulations are misguidedcosting time and money, but yielding no substantial environmental benefit. Unlike other environmental acts, SMCRA details specifically the goals of reclamation and the methods that must be implemented to meet these goals. Coal industry representatives believe that this discourages innovation, promotes inefficiency by ignoring regional differences among sites, and results in unnecessary expense to the industry. Reclamation practices and progress among western coal mining companies are evaluated. (1 map, 5 photos)

  9. One-loop gluon amplitude for heavy-quark production at next-to-next-to-leading order

    SciTech Connect (OSTI)

    Anastasiou, Charalampos; Aybat, S. Mert

    2008-12-01

    We compute the one-loop QCD amplitude for the process gg{yields}QQ in dimensional regularization through order {epsilon}{sup 2} in the dimensional regulator and for arbitrary quark mass values. This result is an ingredient of the next-to-next-to-leading order cross section for heavy-quark production at hadron colliders. The calculation is performed in conventional dimensional regularization using well-known reduction techniques as well as a method based on recent ideas for the functional form of one-loop integrands in four dimensions.

  10. certification, compliance and enforcement regulations for Commercial

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Refrigeration Equipment (CRE) | Department of Energy certification, compliance and enforcement regulations for Commercial Refrigeration Equipment (CRE) certification, compliance and enforcement regulations for Commercial Refrigeration Equipment (CRE) The current certification, compliance and enforcement regulations for Commercial Refrigeration Equipment (CRE) "simply makes no sense". The regulations define the basic model as any product that has a different energy use or efficiency

  11. Investment and regulation: the Dutch experience

    SciTech Connect (OSTI)

    Haffner, Robert; Helmer, Dorine; van Til, Harry

    2010-06-15

    Theoretical studies on the relationship between incentive regulation and investment in network industries generally point out that incentive regulation has a negative impact on investment. However, empirical evidence in this area is scarce. An analysis suggests that in the Dutch electricity and gas networks since 2001, incentive regulation has ensured a more rational and professional approach towards investments, with investment levels coming down somewhat at the start of the regulation but picking up later on. (author)

  12. Regulations for beneficial use changing nationwide

    SciTech Connect (OSTI)

    Goss, D.

    2008-07-01

    Regulations on the use of coal combustion products (CCPs) that are being considered by various US states are reviewed.

  13. Transcriptomic analysis in the developing zebrafish embryo after compound exposure: Individual gene expression and pathway regulation

    SciTech Connect (OSTI)

    Hermsen, Sanne A.B.; Pronk, Tessa E.; Brandhof, Evert-Jan van den; Ven, Leo T.M. van der; Piersma, Aldert H.

    2013-10-01

    The zebrafish embryotoxicity test is a promising alternative assay for developmental toxicity. Classically, morphological assessment of the embryos is applied to evaluate the effects of compound exposure. However, by applying differential gene expression analysis the sensitivity and predictability of the test may be increased. For defining gene expression signatures of developmental toxicity, we explored the possibility of using gene expression signatures of compound exposures based on commonly expressed individual genes as well as based on regulated gene pathways. Four developmental toxic compounds were tested in concentration-response design, caffeine, carbamazepine, retinoic acid and valproic acid, and two non-embryotoxic compounds, D-mannitol and saccharin, were included. With transcriptomic analyses we were able to identify commonly expressed genes, which were mostly development related, after exposure to the embryotoxicants. We also identified gene pathways regulated by the embryotoxicants, suggestive of their modes of action. Furthermore, whereas pathways may be regulated by all compounds, individual gene expression within these pathways can differ for each compound. Overall, the present study suggests that the use of individual gene expression signatures as well as pathway regulation may be useful starting points for defining gene biomarkers for predicting embryotoxicity. - Highlights: The zebrafish embryotoxicity test in combination with transcriptomics was used. We explored two approaches of defining gene biomarkers for developmental toxicity. Four compounds in concentration-response design were tested. We identified commonly expressed individual genes as well as regulated gene pathways. Both approaches seem suitable starting points for defining gene biomarkers.

  14. Plants having modified response to ethylene by transformation with an ETR nucleic acid

    DOE Patents [OSTI]

    Meyerowitz, Elliott M. (Pasadena, CA); Chang, Caren (Pasadena, CA); Bleecker, Anthony B. (Madison, WI)

    2001-01-01

    The invention includes transformed plants having at least one cell transformed with a modified ETR nucleic acid. Such plants have a phenotype characterized by a decrease in the response of at least one transformed plant cell to ethylene as compared to a plant not containing the transformed plant cell. Tissue and/or temporal specificity for expression of the modified ETR nucleic acid is controlled by selecting appropriate expression regulation sequences to target the location and/or time of expression of the transformed nucleic acid. The plants are made by transforming at least one plant cell with an appropriate modified ETR nucleic acid, regenerating plants from one or more of the transformed plant cells and selecting at least one plant having the desired phenotype.

  15. Environmental Laws and Regulations | Department of Energy

    Office of Environmental Management (EM)

    Environmental Laws and Regulations Environmental Laws and Regulations This document defines and explains the environmental laws and regulations that direct our program. Specifically the document discusses: The Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) The Resource Conservation and Recovery Act of 1976 (RCRA) The National Environmental Policy Act (NEPA) Federal Facility Agreement (FFA) Superfund Records of Decisions Removal Actions Administrative Record Files

  16. Guidance Regarding NEPA Regulations | Department of Energy

    Office of Environmental Management (EM)

    NEPA Regulations Guidance Regarding NEPA Regulations This document provides Council on Environmental Quality guidance on several topics: scoping, categorical exclusions, adoption procedures, contracting provisions, selection of alternatives in licensing and permitting situations, and tiering. PDF icon Guidance Regarding NEPA Regulations More Documents & Publications Final Guidance for Effective Use of Programmatic NEPA Review Forty Most Asked Questions Concerning CEQ's National Environmental

  17. Fnr (EtrA) acts as a fine-tuning regulator of anaerobic metabolism in

    Office of Scientific and Technical Information (OSTI)

    Shewanella oneidensis MR-1 (Journal Article) | SciTech Connect Journal Article: Fnr (EtrA) acts as a fine-tuning regulator of anaerobic metabolism in Shewanella oneidensis MR-1 Citation Details In-Document Search Title: Fnr (EtrA) acts as a fine-tuning regulator of anaerobic metabolism in Shewanella oneidensis MR-1 EtrA in Shewanella oneidensis MR-1, a model organism for study of adaptation to varied redox niches, shares 73.6% and 50.8% amino acid sequence identity with the oxygen-sensing

  18. USE OF CHEMICAL INVENTORY ACCURACY MEASUREMENTS AS LEADING INDICATORS

    SciTech Connect (OSTI)

    Kuntamukkula, M.

    2011-02-10

    Chemical safety and lifecycle management (CSLM) is a process that involves managing chemicals and chemical information from the moment someone begins to order a chemical and lasts through final disposition(1). Central to CSLM is tracking data associated with chemicals which, for the purposes of this paper, is termed the chemical inventory. Examples of data that could be tracked include chemical identity, location, quantity, date procured, container type, and physical state. The reason why so much data is tracked is that the chemical inventory supports many functions. These functions include emergency management, which depends upon the data to more effectively plan for, and respond to, chemical accidents; environmental management that uses inventory information to aid in the generation of various federally-mandated and other regulatory reports; and chemical management that uses the information to increase the efficiency and safety with which chemicals are stored and utilized. All of the benefits of having an inventory are predicated upon having an inventory that is reasonably accurate. Because of the importance of ensuring one's chemical inventory is accurate, many have become concerned about measuring inventory accuracy. But beyond providing a measure of confidence in information gleaned from the inventory, does the inventory accuracy measurement provide any additional function? The answer is 'Yes'. It provides valuable information that can be used as a leading indicator to gauge the health of a chemical management system. In this paper, we will discuss: what properties make leading indicators effective, how chemical inventories can be used as a leading indicator, how chemical inventory accuracy can be measured, what levels of accuracies should realistically be expected in a healthy system, and what a subpar inventory accuracy measurement portends.

  19. Alkali-lead-iron phosphate glass and associated method

    DOE Patents [OSTI]

    Boatner, Lynn A. (Oak Ridge, TN); Sales, Brian C. (Knoxville, TN); Franco, Sofia C. S. (Santafe de Bogota, CO)

    1994-01-01

    A glass composition and method of preparation utilizes a mixture consisting of phosphorus oxide within the range of about 40 to 49 molar percent, lead oxide within the range of about 10 to 25 molar percent, iron oxide within the range of about 10 to 17 molar percent and an alkali oxide within the range of about 23 to 30 molar percent. The glass resulting from the melting and subsequent solidifying of the mixture possesses a high degree of durability and a coefficient of thermal expansion as high as that of any of a number of metals. Such features render this glass highly desirable in glass-to-metal seal applications.

  20. Alkali-lead-iron phosphate glass and associated method

    DOE Patents [OSTI]

    Boatner, L.A.; Sales, B.C.; Franco, S.C.S.

    1994-03-29

    A glass composition and method of preparation utilizes a mixture consisting of phosphorus oxide within the range of about 40 to 49 molar percent, lead oxide within the range of about 10 to 25 molar percent, iron oxide within the range of about 10 to 17 molar percent and an alkali oxide within the range of about 23 to 30 molar percent. The glass resulting from the melting and subsequent solidifying of the mixture possesses a high degree of durability and a coefficient of thermal expansion as high as that of any of a number of metals. Such features render this glass highly desirable in glass-to-metal seal applications. 6 figures.

  1. Energy recovery experiment could lead way to new accelerators | Jefferson

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Lab One of four BE magnets Corey Butler, mechanical designer; (left to right) Alex Bogacz, CASA staff scientist and experiment co-spokesman; and Robby Hicks, mechanical engineer, stand with one of the four BE magnets and a section of vacuum chamber built by the Machine Shop specifically for the Energy Recovery experiment. Energy recovery experiment could lead way to new accelerators March 6, 2003 Jefferson Lab physicists will soon begin their own version of reuse - not with run-of-the-mill

  2. Dr. Dave Moody to Lead the Carlsbad Field Office

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ws U.S. Department of Energy Carlsbad Field Office Waste Isolation Pilot Plant P.O. Box 3090 Carlsbad, New Mexico 88221 DOENews For Immediate Release Dr. Dave Moody to lead the Carlsbad Field Office CARLSBAD, N.M., December 12, 2005 - The U.S. Department of Energy (DOE) announced today that long-time Los Alamos National Laboratory (LANL) scientist Dr. Dave Moody will be the new manager of the Carlsbad Field Office (CBFO). Moody began work December 12, filling the position that was previously

  3. Helping the utility compete and comply: Lessons learned lead to informed decision making for NO{sub x} emission reductions

    SciTech Connect (OSTI)

    Cochran, J.R.; Gregory, M.G.; Rummenhohl, V.

    1995-12-31

    Utilities are facing complex decisions regarding system compliance with emission regulations. Both Title I and Title IV of the 1990 Clean Air Act Amendments (CAAA) have requirements for additional reduction of nitrogen oxides (NO{sub x}) emissions. These regulations of the CAAA will be issued through various vessels such as State Implementation Plans (SIPs) and the mandates of the Northeast Ozone Transport Region (NOTR). Once implemented, NOTR regulations will likely require the reduction of NO{sub x} emissions to a level approximately 55 to 65 percent from baseline. As the rules for governing these environmental mandates are finalized, it is anticipated that utilities will be allowed a large amount of flexibility in determining appropriate control strategies for their systems. For example, intrastate and possibly even interstate trading (similar to the SO{sub 2} Acid Rain Program) of emission reduction will likely be allowed. Also, a {open_quotes}seasonal{close_quotes} approach to NO{sub x} emission controls is being considered since ozone nonattainment episodes normally take place during the summer months. Determining the optimum combination of these widely differing alternatives for system wide compliance is the crux of utilities` dilemmas.

  4. Performance optimization of solar cells based on colloidal lead sulfide nanocrystals

    SciTech Connect (OSTI)

    Ulfa, Maria

    2014-02-24

    Colloidal semiconducting quantum dot nanocrystals (NCs) have attracted extensive interest as active building-block for low-cost solution-processed photovoltaic due to their size tunable absorption from the visible to near IR. Among various nanocrystal composition, lead sulfide (PbS), having a bulk bandgap of 0.41 eV, are particularly attractive for photovoltaic applications due to their excellent photosensitivity in the near IR. Starting from colloidal synthesis, in this project functional solar cells are fabricated and characterized based on the nearly monodispersed colloidal PbS nanocrystals that we synthesized. These NC-solar cells are fabricated under a “depleted heterojunction” device architecture containing a planar “tipe II” heretojunction formed by a layer of electron-transporting TiO{sub 2} and a layer of PbS NCs. Relevant structural, optical, and electrical characterizations are performed on NCs and their devices. To understand the operational mechanism of these NC-based solar cells, various material and device aspects are investigated in this work aiming for optimized photovoltaic performance. These aspects include the effect of: (1) NC dimensions (and thus their band gaps); (2) passivation of surface traps through post-synthesis treatments; (3) NC surface ligand-exchange; and (4) interfacial modifications at the heterojunction. The most optimized photovoltaic performance is found after combining the surface trap passivation strategy by halides, ligand-exchange by 3-mercaptopropionic acids, and interfacial TiCl4 treatment, leading to a peak open-circuit voltage of 0.53 V, a short-circuit current density of 14.03 mAcm{sup −2}, and a power conversion efficiency of 3.25%.

  5. Physiology and Regulation of Calcium Channels in Stomatal Guard Cells

    SciTech Connect (OSTI)

    Schroeder, Julian I.

    2007-05-02

    Stomatal pores in the epidermis of leaves regulate the diffusion of CO2 into leaves for photosynthetic carbon fixation and control water loss of plants during drought periods. Guard cells sense CO2, water status, light and other environmental conditions to regulate stomatal apertures for optimization of CO2 intake and plant growth under drought stress. The cytosolic second messenger calcium contributes to stomatal movements by transducing signals and regulating ion channels in guard cells. Studies suggest that both plasma membrane Ca2+ influx channels and vacuolar/organellar Ca2+ release channels contribute to ABA-induced Ca2+ elevations in guard cells. Recent research in the P.I.'s laboratory has led to identification of a novel major cation-selective Ca2+-permeable influx channel (Ica) in the plasma membrane of Arabidopsis guard cells. These advances will allow detailed characterization of Ica plasma membrane Ca2+ influx channels in guard cells. The long term goal of this research project is to gain a first detailed characterization of these novel plasma membrane Ca2+-permeable channel currents in Arabidopsis guard cells. The proposed research will investigate the hypothesis that Ica represents an important Ca2+ influx pathway for ABA and CO2 signal transduction in Arabidopsis guard cells. These studies will lead to elucidation of key signal transduction mechanisms by which plants balance CO2 influx into leaves and transpirational water loss and may contribute to future strategies for manipulating gas exchange for improved growth of crop plants and for biomass production.

  6. Collisions of deformable cells lead to collective migration

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Löber, Jakob; Ziebert, Falko; Aranson, Igor S.

    2015-03-17

    Collective migration of eukaryotic cells plays a fundamental role in tissue growth, wound healing and immune response. The motion, arising spontaneously or in response to chemical and mechanical stimuli, is also important for understanding life-threatening pathologies, such as cancer and metastasis formation. We present a phase-field model to describe the movement of many self-organized, interacting cells. The model takes into account the main mechanisms of cell motility – acto-myosin dynamics, as well as substrate-mediated and cell-cell adhesion. It predicts that collective cell migration emerges spontaneously as a result of inelastic collisions between neighboring cells: collisions lead to a mutual alignmentmore » of the cell velocities and to the formation of coherently-moving multi-cellular clusters. Small cell-to-cell adhesion, in turn, reduces the propensity for large-scale collective migration, while higher adhesion leads to the formation of moving bands. Our study provides valuable insight into biological processes associated with collective cell motility.« less

  7. Collisions of deformable cells lead to collective migration

    SciTech Connect (OSTI)

    Löber, Jakob; Ziebert, Falko; Aranson, Igor S.

    2015-03-17

    Collective migration of eukaryotic cells plays a fundamental role in tissue growth, wound healing and immune response. The motion, arising spontaneously or in response to chemical and mechanical stimuli, is also important for understanding life-threatening pathologies, such as cancer and metastasis formation. We present a phase-field model to describe the movement of many self-organized, interacting cells. The model takes into account the main mechanisms of cell motility – acto-myosin dynamics, as well as substrate-mediated and cell-cell adhesion. It predicts that collective cell migration emerges spontaneously as a result of inelastic collisions between neighboring cells: collisions lead to a mutual alignment of the cell velocities and to the formation of coherently-moving multi-cellular clusters. Small cell-to-cell adhesion, in turn, reduces the propensity for large-scale collective migration, while higher adhesion leads to the formation of moving bands. Our study provides valuable insight into biological processes associated with collective cell motility.

  8. Staff Listing - Office of Regulation and International Engagement, Division

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of Natural Gas Regulation, Division of International Engagement | Department of Energy Staff Listing - Office of Regulation and International Engagement, Division of Natural Gas Regulation, Division of International Engagement Staff Listing - Office of Regulation and International Engagement, Division of Natural Gas Regulation, Division of International Engagement Office of Regulation and International Engagement Mailing Address: Office of Regulation and International Engagement Office of

  9. Fuel cell electrolyte membrane with acidic polymer

    DOE Patents [OSTI]

    Hamrock, Steven J. (Stillwater, MN); Larson, James M. (Saint Paul, MN); Pham, Phat T. (Little Canada, MN); Frey, Matthew H. (Cottage Grove, MN); Haugen, Gregory M. (Edina, MN); Lamanna, William M. (Stillwater, MN)

    2009-04-14

    An electrolyte membrane is formed by an acidic polymer and a low-volatility acid that is fluorinated, substantially free of basic groups, and is either oligomeric or non-polymeric.

  10. Recovery of mercury from acid waste residues

    DOE Patents [OSTI]

    Greenhalgh, W.O.

    1987-02-27

    Mercury can be recovered from nitric acid-containing fluids by reacting the fluid with aluminum metal to produce mercury metal, and thence quenching the reactivity of the nitric acid prior to nitration of the mercury metal. 1 fig.

  11. Replica amplification of nucleic acid arrays

    DOE Patents [OSTI]

    Church, George M.

    2002-01-01

    A method of producing a plurality of a nucleic acid array, comprising, in order, the steps of amplifying in situ nucleic acid molecules of a first randomly-patterned, immobilized nucleic acid array comprising a heterogeneous pool of nucleic acid molecules affixed to a support, transferring at least a subset of the nucleic acid molecules produced by such amplifying to a second support, and affixing the subset so transferred to the second support to form a second randomly-patterned, immobilized nucleic acid array, wherein the nucleic acid molecules of the second array occupy positions that correspond to those of the nucleic acid molecules from which they were amplified on the first array, so that the first array serves as a template to produce a plurality, is disclosed.

  12. Recovery of mercury from acid waste residues

    DOE Patents [OSTI]

    Greenhalgh, Wilbur O. (Richland, WA)

    1989-01-01

    Mercury can be recovered from nitric acid-containing fluids by reacting the fluid with aluminum metal to produce mercury metal, and then quenching the reactivity of the nitric acid prior to nitration of the mercury metal.

  13. Capture and release of acid-gasses with acid-gas binding organic compounds

    DOE Patents [OSTI]

    Heldebrant, David J; Yonker, Clement R; Koech, Phillip K

    2015-03-17

    A system and method for acid-gas capture wherein organic acid-gas capture materials form hetero-atom analogs of alkyl-carbonate when contacted with an acid gas. These organic-acid gas capture materials include combinations of a weak acid and a base, or zwitterionic liquids. This invention allows for reversible acid-gas binding to these organic binding materials thus allowing for the capture and release of one or more acid gases. These acid-gas binding organic compounds can be regenerated to release the captured acid gasses and enable these organic acid-gas binding materials to be reused. This enables transport of the liquid capture compounds and the release of the acid gases from the organic liquid with significant energy savings compared to current aqueous systems.

  14. Thermal Stability Of Formohydroxamic Acid

    SciTech Connect (OSTI)

    Fondeur, F. F.; Rudisill, T. S.

    2011-10-21

    The thermal stability of formohydroxamic acid (FHA) was evaluated to address the potential for exothermic decomposition during storage and its use in the uranium extraction process. Accelerating rate calorimetry showed rapid decomposition at a temperature above 65 {degree}?C; although, the rate of pressure rise was greater than two orders of magnitude less than the lower bound for materials which have no explosive properties with respect to transportation. FHA solutions in water and nitric acid did not reach runaway conditions until 150 {degree}?C. Analysis by differential scanning calorimetry showed that FHA melted at 67 {degree}?C and thermally decomposed at 90 {degree}?C with an enthalpy of -1924 J/g. The energics of the FHA thermal decomposition are comparable to those measured for aqueous solutions of hydroxylamine nitrate. Solid FHA should be stored in a location where the temperature does not exceed 20-25 {degree}?C. As a best practice, the solid material should be stored in a climate-controlled environment such as a refrigerator or freezer. FHA solutions in water are not susceptible to degradation by acid hydrolysis and are the preferred way to handle FHA prior to use.

  15. Production of high molecular weight polylactic acid

    DOE Patents [OSTI]

    Bonsignore, P.V.

    1995-11-28

    A degradable high molecular weight poly(lactic acid) is described. The poly(lactic acid) has a terminal end group of one of carboxyl or hydroxyl groups with low molecular weight poly(lactic acid) units coupled with linking agents of di-isocyanates, bis-epoxides, bis-oxazolines and bis-ortho esters. The resulting high molecular weight poly(lactic acid) can be used for applications taking advantage of the improved physical properties.

  16. Production of high molecular weight polylactic acid

    DOE Patents [OSTI]

    Bonsignore, Patrick V. (Joilet, IL)

    1995-01-01

    A degradable high molecular weight poly(lactic acid). A poly(lactic acid) has a terminal end group of one of carboxyl or hydroxyl groups with low molecular weight poly(lactic acid) units coupled with linking agents of di-isocyanates, bis-epoxides, bis-oxazolines and bis-ortho esters. The resulting high molecular weight poly(lactic acid) can be used for applications taking advantage of the improved physical properties.

  17. Lactic acid-producing yeast cells having nonfunctional L- or D-lactate:ferricytochrome C oxidoreductase cells

    DOE Patents [OSTI]

    Miller, Matthew; Suominen, Pirkko; Aristidou, Aristos; Hause, Benjamin Matthew; Van Hoek, Pim; Dundon, Catherine Asleson

    2012-03-20

    Yeast cells having an exogenous lactate dehydrogenase gene ae modified by reducing L- or D-lactate:ferricytochrome c oxidoreductase activity in the cell. This leads to reduced consumption of lactate by the cell and can increase overall lactate yields in a fermentation process. Cells having the reduced L- or D-lactate:ferricytochrome c oxidoreductase activity can be screened for by resistance to organic acids such as lactic or glycolic acid.

  18. Synthesis of an acid addition salt of delta-aminolevulinic acid from 5-bromo levulinic acid esters

    DOE Patents [OSTI]

    Moens, L.

    1999-05-25

    A process is disclosed for preparing an acid addition salt of delta-aminolevulinic acid comprising. The process involves dissolving a lower alkyl 5-bromolevulinate and an alkali metal diformylamide in an organic solvent selected from the group consisting of acetonitrile, methanol, tetrahydrofuran, 2-methyltetrahydrofuran and methylformate or mixtures to form a suspension of an alkyl 5-(N,N-diformylamino) levulinate ester; and hydrolyzing the alkyl 5-(N,N-diformylamino) levulinate with an inorganic acid to form an acid addition salt of delta-amino levulinic acid.

  19. Synthesis of an acid addition salt of delta-aminolevulinic acid from 5-bromo levulinic acid esters

    DOE Patents [OSTI]

    Moens, Luc (Lakewood, CO)

    1999-01-01

    A process of preparing an acid addition salt of delta-aminolevulinic acid comprising: dissolving a lower alkyl 5-bromolevulinate and an alkali metal diformylamide in an organic solvent selected from the group consisting of acetonitrile, methanol, tetrahydrofuran, 2-methyltetrahydrofuran and methylformate or mixtures thereof to form a suspension of an alkyl 5-(N,N-diformylamino) levulinate ester; and hydrolyzing said alkyl 5-(N,N-diformylamino) levulinate with an inorganic acid to form an acid addition salt of delta-amino levulinic acid.

  20. Unnatural reactive amino acid genetic code additions

    DOE Patents [OSTI]

    Deiters, Alexander; Cropp, T. Ashton; Chin, Jason W.; Anderson, J. Christopher; Schultz, Peter G.

    2014-08-26

    This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.

  1. Unnatural reactive amino acid genetic code additions

    DOE Patents [OSTI]

    Deiters, Alexander; Cropp, Ashton T; Chin, Jason W; Anderson, Christopher J; Schultz, Peter G

    2013-05-21

    This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.

  2. Unnatural reactive amino acid genetic code additions

    DOE Patents [OSTI]

    Deiters, Alexander (La Jolla, CA); Cropp, T. Ashton (San Diego, CA); Chin, Jason W. (Cambridge, GB); Anderson, J. Christopher (San Francisco, CA); Schultz, Peter G. (La Jolla, CA)

    2011-02-15

    This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.

  3. Unnatural reactive amino acid genetic code additions

    DOE Patents [OSTI]

    Deiters, Alexander (La Jolla, CA); Cropp, T. Ashton (Bethesda, MD); Chin, Jason W. (Cambridge, GB); Anderson, J. Christopher (San Francisco, CA); Schultz, Peter G. (La Jolla, CA)

    2011-08-09

    This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNAsyn-thetases, pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.

  4. Medium Power Lead Alloy Fast Reactor Balance of Plant Options

    SciTech Connect (OSTI)

    Vaclav Dosta; Pavel Hejzlar; Neil E. Todreas; Jacopo Buongiorno

    2004-09-01

    Proper selection of the power conversion cycle is a very important step in the design of a nuclear reactor. Due to the higher core outlet temperature (~550C) compared to that of light water reactors (~300C), a wide portfolio of power cycles is available for the lead alloy fast reactor (LFR). Comparison of the following cycles for the LFR was performed: superheated steam (direct and indirect), supercritical steam, helium Brayton, and supercritical CO2 (S-CO2) recompression. Heat transfer from primary to secondary coolant was first analyzed and then the steam generators or heat exchangers were designed. The direct generation of steam in the lead alloy coolant was also evaluated. The resulting temperatures of the secondary fluids are in the range of 530-545C, dictated by the fixed space available for the heat exchangers in the reactor vessel. For the direct steam generation situation, the temperature is 312C. Optimization of each power cycle was carried out, yielding net plant efficiency of around 40% for the superheated steam cycle while the supercritical steam and S-CO2 cycles achieved net plant efficiency of 41%. The cycles were then compared based on their net plant efficiency and potential for low capital cost. The superheated steam cycle is a very good candidate cycle given its reasonably high net plant efficiency and ease of implementation based on the extensive knowledge and operating experience with this cycle. Although the supercritical steam cycle net plant efficiency is slightly better than that of the superheated steam cycle, its high complexity and high pressure result in higher capital cost, negatively affecting plant economics. The helium Brayton cycle achieves low net plant efficiency due to the low lead alloy core outlet temperature, and therefore, even though it is a simpler cycle than the steam cycles, its performance is mediocre in this application. The prime candidate, however, appears to be the S-CO2 recompression cycle, because it achieves about the same net plant efficiency as the supercritical steam cycle and is significantly simpler than the steam cycles. Moreover, the S-CO2 cycle offers a significantly higher potential for an increase in efficiency than steam cycles, after better materials allow the LFR operating temperatures to be increased. Therefore, the S-CO2 is chosen as the reference cycle for the LFR, with the superheated or supercritical steam cycles as backups if the S-CO2 cycle development efforts do not succeed.

  5. Title 27 California Code of Regulations: Environmental Protection...

    Open Energy Info (EERE)

    7 California Code of Regulations: Environmental Protection Jump to: navigation, search OpenEI Reference LibraryAdd to library Legal Document- RegulationRegulation: Title 27...

  6. Rules and Regulations of the Wyoming Industrial Siting Council...

    Open Energy Info (EERE)

    Document- RegulationRegulation: Rules and Regulations of the Wyoming Industrial Siting Council - Chapter 1Legal Abstract Industrial development information and siting rules and...

  7. Advisory Council on Historic Preservation - Section 106 Regulations...

    Open Energy Info (EERE)

    OpenEI Reference LibraryAdd to library Legal Document- RegulationRegulation: Advisory Council on Historic Preservation - Section 106 RegulationsLegal Abstract Section 106 requires...

  8. Rules and Regulations of the Wyoming Industrial Siting Council...

    Open Energy Info (EERE)

    Document- RegulationRegulation: Rules and Regulations of the Wyoming Industrial Siting Council - Chapter 2Legal Abstract Rules of practice and proceedures of the Industrial Siting...

  9. Rules and Regulations of the Industrial Siting Council, Chapter...

    Open Energy Info (EERE)

    Industrial Siting Council, Chapter 1 Jump to: navigation, search OpenEI Reference LibraryAdd to library Legal Document- RegulationRegulation: Rules and Regulations of the...

  10. 18 CFR 380 Regulations Implementing the National Environmental...

    Open Energy Info (EERE)

    380 Regulations Implementing the National Environmental Policy Act Jump to: navigation, search OpenEI Reference LibraryAdd to library Legal Document- RegulationRegulation: 18 CFR...

  11. Chapter 9 of the Wyoming Public Service Commission Regulations...

    Open Energy Info (EERE)

    9 of the Wyoming Public Service Commission Regulations: General Forms Jump to: navigation, search OpenEI Reference LibraryAdd to library Legal Document- RegulationRegulation:...

  12. 2011 Air Quality Regulations Report | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Air Quality Regulations Report 2011 Air Quality Regulations Report PDF icon 2011 Air Quality Regulations Report120111.pdf More Documents & Publications 2011:...

  13. 2011: Air Quality Regulations Report | Department of Energy

    Office of Environmental Management (EM)

    : Air Quality Regulations Report 2011: Air Quality Regulations Report PDF icon 2011 Air Quality Regulations ReportA120911.pdf More Documents & Publications 2011...

  14. WAC - 173-303 Dangerous Waste Regulations | Open Energy Information

    Open Energy Info (EERE)

    03 Dangerous Waste Regulations Jump to: navigation, search OpenEI Reference LibraryAdd to library Legal Document- RegulationRegulation: WAC - 173-303 Dangerous Waste...

  15. LABORATORY STUDIES ON THE FORMATION OF FORMIC ACID (HCOOH) IN INTERSTELLAR AND COMETARY ICES

    SciTech Connect (OSTI)

    Bennett, Chris J.; Kim, Yong Seol; Kaiser, Ralf I.; Hama, Tetsuya; Kawasaki, Masahiro

    2011-01-20

    Mixtures of water (H{sub 2}O) and carbon monoxide (CO) ices were irradiated at 10 K with energetic electrons to simulate the energy transfer processes that occur in the track of galactic cosmic-ray particles penetrating interstellar ices. We identified formic acid (HCOOH) through new absorption bands in the infrared spectra at 1690 and 1224 cm{sup -1} (5.92 and 8.17 {mu}m, respectively). During the subsequent warm-up of the irradiated samples, formic acid is evident from the mass spectrometer signal at the mass-to-charge ratio, m/z = 46 (HCOOH{sup +}) as the ice sublimates. The detection of formic acid was confirmed using isotopically labeled water-d2 with carbon monoxide, leading to formic acid-d2 (DCOOD). The temporal fits of the reactants, reaction intermediates, and products elucidate two reaction pathways to formic acid in carbon monoxide-water ices. The reaction is induced by unimolecular decomposition of water forming atomic hydrogen (H) and the hydroxyl radical (OH). The dominating pathway to formic acid (HCOOH) was found to involve addition of suprathermal hydrogen atoms to carbon monoxide forming the formyl radical (HCO); the latter recombined with neighboring hydroxyl radicals to yield formic acid (HCOOH). To a lesser extent, hydroxyl radicals react with carbon monoxide to yield the hydroxyformyl radical (HOCO), which recombined with atomic hydrogen to produce formic acid. Similar processes are expected to produce formic acid within interstellar ices, cometary ices, and icy satellites, thus providing alternative processes for the generation of formic acid whose abundance in hot cores such as Sgr-B2 cannot be accounted for solely by gas-phase chemistry.

  16. Symmetries and multiferroic properties of novel room-temperature magnetoelectrics: Lead iron tantalate lead zirconate titanate (PFT/PZT)

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Sanchez, Dilsom A.; Ortega, N.; Kumar, Ashok; Roque-Malherbe, R.; Polanco, R.; Scott, J. F.; Katiyar, Ram S.

    2011-12-01

    Mixing 60-70% lead zirconate titanate with 40-30% lead iron tantalate produces a single-phase, low-loss, room-temperature multiferroic with magnetoelectric coupling: (PbZr?.??Ti?.??O?) (1-x)- (PbFe?.?Ta?.?O?)x. The present study combines x-ray scattering, magnetic and polarization hysteresis in both phases, plus a second-order dielectric divergence (to epsilon = 6000 at 475 K for 0.4 PFT; to 4000 at 520 K for 0.3 PFT) for an unambiguous assignment as a C2v-C4v (Pmm2-P4mm) transition. The material exhibits square saturated magnetic hysteresis loops with 0.1 emu/g at 295 K and saturation polarization Pr = 25 ?C/cm, which actually increases (to 40 ?C/cm) in the high-T tetragonal phase, representingmorean exciting new room temperature oxide multiferroic to compete with BiFeO?. Additional transitions at high temperatures (cubic at T>1300 K) and low temperatures (rhombohedral or monoclinic at Tless

  17. An evaluation of worker lead exposures and cleaning effectiveness during removal of deteriorated lead-based paint

    SciTech Connect (OSTI)

    Sussell, A.; Wild, D.; Ashley, K.; Hart, C.

    1999-03-01

    The authors evaluated worker lead exposures and cleaning effectiveness during initial cleanup of 19th-century buildings with highly deteriorated lead-based paint. Eighteen rooms of similar size and condition in two university-owned buildings were selected for a pilot project to compare three methods for removing loose paint, paint chips, and dust. The methods used were: dry scraping followed by dry sweeping (no engineering or work practice controls); wet scraping and high-efficiency particulate air (HEPA) vacuuming; and the latter method with the addition of a portable HEPA-filtered exhaust fan in the room providing about 40 air changes per hour. The final step for all methods was wet-mopping once with tri-sodium phosphate solution. During a single day 18 rooms were cleaned; each of three two-person work crews cleaned six room, two with each method. Air and surface samples were collected before, during, and after cleaning. All of the methods were potentially hazardous to workers: 44% of the method-based exposures and one of five full-shift exposures exceeded the OSHA PEL.

  18. Atomic vapor laser isotope separation of lead-210 isotope

    DOE Patents [OSTI]

    Scheibner, K.F.; Haynam, C.A.; Johnson, M.A.; Worden, E.F.

    1999-08-31

    An isotopically selective laser process and apparatus for removal of Pb-210 from natural lead that involves a one-photon near-resonant, two-photon resonant excitation of one or more Rydberg levels, followed by field ionization and then electrostatic extraction. The wavelength to the near-resonant intermediate state is counter propagated with respect to the second wavelength required to populate the final Rydberg state. This scheme takes advantage of the large first excited state cross section, and only modest laser fluences are required. The non-resonant process helps to avoid two problems: first, stimulated Raman Gain due to the nearby F=3/2 hyperfine component of Pb-207 and, second, direct absorption of the first transition process light by Pb-207. 5 figs.

  19. Richard Gerber! NERSC Senior Science Advisor! User Services Group Lead

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    User Services Group Lead NUG Webinar January 2014 --- 1 --- January 9 , 2 014 Agenda * Edison C onfigura6on f or A Y 2 014 * Alloca6on Y ear R ollover I ssues * Project D irectories p er P roject * NUG 2 014 U ser G roup M ee6ng * Automa6c I /O P rofiling f or Y our C ode * Give / T ake U 6lity f or S haring F iles * NUG Q ueue C ommiRee U pdate * User Survey Needs Your Input * Open D iscussion --- 2 --- Edison Update --- 3 --- Jeff B roughton NERSC D eputy f or O pera6ons Systems D epartment H

  20. Atomic vapor laser isotope separation of lead-210 isotope

    DOE Patents [OSTI]

    Scheibner, Karl F. (Tracy, CA); Haynam, Christopher A. (Pleasanton, CA); Johnson, Michael A. (Pleasanton, CA); Worden, Earl F. (Diablo, CA)

    1999-01-01

    An isotopically selective laser process and apparatus for removal of Pb-210 from natural lead that involves a one-photon near-resonant, two-photon resonant excitation of one or more Rydberg levels, followed by field ionization and then electrostatic extraction. The wavelength to the near-resonant intermediate state is counter propagated with respect to the second wavelength required to populate the final Rydberg state. This scheme takes advantage of the large first excited state cross section, and only modest laser fluences are required. The non-resonant process helps to avoid two problems: first, stimulated Raman Gain due to the nearby F=3/2 hyperfine component of Pb-207 and, second, direct absorption of the first transition process light by Pb-207.