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1

RADIATION ONCOLOGY TARGET YOUR FUTURE  

E-Print Network (OSTI)

. · Radiation therapist - a health professional who designs, calculates (plans) and provides the radiation dose and monitors the delivery of radiation therapy, taking into account the protection and safety of patientsRADIATION ONCOLOGY TARGET YOUR FUTURE #12;A Career in Radiation Oncology YOUR CHOICE SAVE LIVES

Tobar, Michael

2

Dr. Jim Wright Acting Head, Division of Radiation Oncology  

E-Print Network (OSTI)

Dr. Jim Wright Acting Head, Division of Radiation Oncology Associate Professor Department outstanding contributions to the care and treatment of cancer patients through research. Dr. Jim Wright has

Haykin, Simon

3

E-Print Network 3.0 - academic radiation oncology Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

McMaster University Collection: Engineering 2 RADIATION ONCOLOGY FREQUENTLY ASKED QUESTIONS -2010 Summary: RADIATION ONCOLOGY FREQUENTLY ASKED QUESTIONS - 2010 Specialty...

4

The structural characteristics of radiation oncology in Japan in 2003  

Science Journals Connector (OSTI)

Purpose: To ascertain the basic structural characteristics of radiation oncology facilities in Japan, we conducted a national survey on their status in 2003. The aims of the survey included the following: present status of radiation treatment facilities, equipment, personnel, patient loads, and other factors. Methods and Materials: A mail survey verified each potential facility delivering megavoltage radiation therapy and collected data on treatment devices, other equipment, personnel, new patients, and so on. Responses were obtained from 100% of potential facilities. Results: A total of 726 facilities delivered radiation therapy, with 859 megavoltage devices, 203 RALS (remote after-loading system) and other radioactive sources, with 941 FTE (full-time employee) radiation oncologists including 369 FTE Japanese Society of Therapeutic Radiation Oncology-certified radiation oncologists, 1555 FTE radiation therapists, and 70 FTE physicists in 2003. Megavoltage devices included two heavy ion units and four proton units. In total, there were 149,793 new patients and 146,351 (98%) by external irradiation; 4379 (3%) were treated by brachytherapy with or without external irradiation. Eighty-six percent of the facilities had treatment-planning computers, but 4% had no treatment-planning capability. Six percent (44 facilities) of all facilities used hyperthermia, 12% (85 facilities) intraoperative radiation therapy, and 2% (12 facilities) intensity-modulated radiation therapy. Conclusion: Facilities surveys continue to provide a source of census data on radiation oncology in Japan, allowing comparisons among facility groups and over time.

Hitoshi Shibuya; Hirohiko Tsujii

2005-01-01T23:59:59.000Z

5

The structural characteristics of radiation oncology in Japan in 2003  

SciTech Connect

Purpose: To ascertain the basic structural characteristics of radiation oncology facilities in Japan, we conducted a national survey on their status in 2003. The aims of the survey included the following: present status of radiation treatment facilities, equipment, personnel, patient loads, and other factors. Methods and Materials: A mail survey verified each potential facility delivering megavoltage radiation therapy and collected data on treatment devices, other equipment, personnel, new patients, and so on. Responses were obtained from 100% of potential facilities. Results: A total of 726 facilities delivered radiation therapy, with 859 megavoltage devices, 203 RALS (remote after-loading system) and other radioactive sources, with 941 FTE (full-time employee) radiation oncologists including 369 FTE Japanese Society of Therapeutic Radiation Oncology-certified radiation oncologists, 1555 FTE radiation therapists, and 70 FTE physicists in 2003. Megavoltage devices included two heavy ion units and four proton units. In total, there were 149,793 new patients and 146,351 (98%) by external irradiation; 4379 (3%) were treated by brachytherapy with or without external irradiation. Eighty-six percent of the facilities had treatment-planning computers, but 4% had no treatment-planning capability. Six percent (44 facilities) of all facilities used hyperthermia, 12% (85 facilities) intraoperative radiation therapy, and 2% (12 facilities) intensity-modulated radiation therapy. Conclusion: Facilities surveys continue to provide a source of census data on radiation oncology in Japan, allowing comparisons among facility groups and over time.

Shibuya, Hitoshi [JASTRO Database Committee, Department of Radiology, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo (Japan)]. E-mail: shibuya.mrad@tmd.ac.jp; Tsujii, Hirohiko [National Institute of Radiological Sciences, Chiba-shi, Chiba (Japan)

2005-08-01T23:59:59.000Z

6

Japanese structure survey of radiation oncology in 2009 with special reference to designated cancer care hospitals  

Science Journals Connector (OSTI)

The structure of radiation oncology in designated cancer care hospitals in Japan was surveyed in terms of equipment, personnel...

Hodaka Numasaki; Masamichi Nishio…

2013-10-01T23:59:59.000Z

7

National structure of radiation oncology in Japan with special reference to designated cancer care hospitals  

Science Journals Connector (OSTI)

The structure of radiation oncology in designated cancer care hospitals in Japan was investigated in terms of equipment, personnel...

Hodaka Numasaki; Teruki Teshima…

2009-06-01T23:59:59.000Z

8

Northwestern University Feinberg School of Medicine  

E-Print Network (OSTI)

1 Northwestern University Feinberg School of Medicine Web Content Style Guide June 2013 #12 ...................................................................................................................................3 What We Know About Web Users Feinberg site, and focus their information for greatest impact to web readers. The document also includes

Engman, David M.

9

Burnout in United States Academic Chairs of Radiation Oncology Programs  

SciTech Connect

Purpose: The aims of this study were to determine the self-reported prevalence of burnout in chairs of academic radiation oncology departments, to identify factors contributing to burnout, and to compare the prevalence of burnout with that seen in other academic chair groups. Methods and Materials: An anonymous online survey was administered to the membership of the Society of Chairs of Academic Radiation Oncology Programs (SCAROP). Burnout was measured with the Maslach Burnout Inventory-Human Services Survey (MBI-HSS). Results: Questionnaires were returned from 66 of 87 chairs (76% response rate). Seventy-nine percent of respondents reported satisfaction with their current positions. Common major stressors were budget deficits and human resource issues. One-quarter of chairs reported that it was at least moderately likely that they would step down in the next 1 to 2 years; these individuals demonstrated significantly higher emotional exhaustion. Twenty-five percent of respondents met the MBI-HSS criteria for low burnout, 75% for moderate burnout, and none for high burnout. Group MBI-HSS subscale scores demonstrated a pattern of moderate emotional exhaustion, low depersonalization, and moderate personal accomplishment, comparing favorably with other specialties. Conclusions: This is the first study of burnout in radiation oncology chairs with a high response rate and using a validated psychometric tool. Radiation oncology chairs share similar major stressors to other chair groups, but they demonstrate relatively high job satisfaction and lower burnout. Emotional exhaustion may contribute to the anticipated turnover in coming years. Further efforts addressing individual and institutional factors associated with burnout may improve the relationship with work of chairs and other department members.

Kusano, Aaron S. [Department of Radiation Oncology, University of Washington School of Medicine, Seattle, Washington (United States); Thomas, Charles R., E-mail: thomasch@ohsu.edu [Department of Radiation Medicine, Knight Cancer Institute/Oregon Health and Science University, Portland, Oregon (United States); Bonner, James A. [Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama (United States); DeWeese, Theodore L. [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medical Institutions, Baltimore, Maryland (United States); Formenti, Silvia C. [Department of Radiation Oncology, New York University, New York, New York (United States); Hahn, Stephen M. [Department of Radiation Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania (United States); Lawrence, Theodore S. [Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan (United States); Mittal, Bharat B. [Department of Radiation Oncology, Northwestern University, Chicago, Ilinois (United States)

2014-02-01T23:59:59.000Z

10

A National Radiation Oncology Medical Student Clerkship Survey: Didactic Curricular Components Increase Confidence in Clinical Competency  

SciTech Connect

Purpose: Students applying to radiation oncology residency programs complete 1 or more radiation oncology clerkships. This study assesses student experiences and perspectives during radiation oncology clerkships. The impact of didactic components and number of clerkship experiences in relation to confidence in clinical competency and preparation to function as a first-year radiation oncology resident are evaluated. Methods and Materials: An anonymous, Internet-based survey was sent via direct e-mail to all applicants to a single radiation oncology residency program during the 2012-2013 academic year. The survey was composed of 3 main sections including questions regarding baseline demographic information and prior radiation oncology experience, rotation experiences, and ideal clerkship curriculum content. Results: The survey response rate was 37% (70 of 188). Respondents reported 191 unique clerkship experiences. Of the respondents, 27% (19 of 70) completed at least 1 clerkship with a didactic component geared towards their level of training. Completing a clerkship with a didactic component was significantly associated with a respondent's confidence to function as a first-year radiation oncology resident (Wilcoxon rank–sum P=.03). However, the total number of clerkships completed did not correlate with confidence to pursue radiation oncology as a specialty (Spearman ? P=.48) or confidence to function as a first year resident (Spearman ? P=.43). Conclusions: Based on responses to this survey, rotating students perceive that the majority of radiation oncology clerkships do not have formal didactic curricula. Survey respondents who completed a clerkship with a didactic curriculum reported feeling more prepared to function as a radiation oncology resident. However, completing an increasing number of clerkships does not appear to improve confidence in the decision to pursue radiation oncology as a career or to function as a radiation oncology resident. These results support further development of structured didactic curricula for the radiation oncology clerkship.

Jagadeesan, Vikrant S. [Department of Radiation and Cellular Oncology, Pritzker School of Medicine, University of Chicago, Chicago, Illinois (United States); Raleigh, David R. [Department of Radiation Oncology, School of Medicine, University of California–San Francisco, San Francisco, California (United States); Koshy, Matthew; Howard, Andrew R.; Chmura, Steven J. [Department of Radiation and Cellular Oncology, Pritzker School of Medicine, University of Chicago, Chicago, Illinois (United States); Golden, Daniel W., E-mail: dgolden@radonc.uchicago.edu [Department of Radiation and Cellular Oncology, Pritzker School of Medicine, University of Chicago, Chicago, Illinois (United States)

2014-01-01T23:59:59.000Z

11

TH?B?110?01: Informatics in Radiation Oncology  

Science Journals Connector (OSTI)

Informatics covers not only the information technology (IT) and infrastructure required to support data collection and management but also the computer science concepts that turn data into knowledge. In radiation oncology medical physicists need to be familiar with the basic IT infrastructure that makes it possible to transfer and transform data through clinical processes that ultimately control radiation treatment delivery. The application of informatics continues with patient outcomes. Typically this happens through participation in national protocols (e.g. RTOG). While they provide a framework for evidence?based medicine the data are often limited to parameters that were designed to test a pre?defined hypothesis. As the ability to acquire and distribute data increases we may be able to adopt data mining approaches to discover knowledge even without asking specific questions. While simple database queries can efficiently provide statistical information (e.g. the NCI Surveillance Epidemiology and End Results SEER) data mining seeks hidden patterns through clustering classification regression and association. These principles can be applied to large volumes of concisely described data sets similar to what can be found in clinical trials. Researchers in radiation oncologyinformatics are developing the infrastructure to acquire large data sets. The Radiation Oncology Data Alliance (RODA) initiative aims to provide online aggregate de?identified data from participating users of the MOSAIQ EMR. Borrowing from the field of astronomy researchers from Johns Hopkins used the SkyServer framework to build the OncoSpace project. The NCI caBIG (Cancer Bioinformatics Grid) also provides infrastructure support. Data analytics have also been developing in parallel with researchers structuring the data collection phases to answer questions in Comparative Effectiveness Research (CER). While a majority of researchers look for links between treatment and outcome others have used informatics to improve not only the efficiency and business of providing care but also its quality and safety which ultimately affects outcome.

R Siochi

2011-01-01T23:59:59.000Z

12

Radiation Oncology Medical Student Clerkship: Implementation and Evaluation of a Bi-institutional Pilot Curriculum  

SciTech Connect

Purpose: To develop and evaluate a structured didactic curriculum to complement clinical experiences during radiation oncology clerkships at 2 academic medical centers. Methods and Materials: A structured didactic curriculum was developed to teach fundamentals of radiation oncology and improve confidence in clinical competence. Curriculum lectures included: (1) an overview of radiation oncology (history, types of treatments, and basic clinic flow); (2) fundamentals of radiation biology and physics; and (3) practical aspects of radiation treatment simulation and planning. In addition, a hands-on dosimetry session taught students fundamentals of treatment planning. The curriculum was implemented at 2 academic departments in 2012. Students completed anonymous evaluations using a Likert scale to rate the usefulness of curriculum components (1 = not at all, 5 = extremely). Likert scores are reported as (median [interquartile range]). Results: Eighteen students completed the curriculum during their 4-week rotation (University of Chicago n=13, Harvard Longwood Campus n=5). All curriculum components were rated as extremely useful: introduction to radiation oncology (5 [4-5]); radiation biology and physics (5 [5-5]); practical aspects of radiation oncology (5 [4-5]); and the treatment planning session (5 [5-5]). Students rated the curriculum as “quite useful” to “extremely useful” (1) to help students understand radiation oncology as a specialty; (2) to increase student comfort with their specialty decision; and (3) to help students with their future transition to a radiation oncology residency. Conclusions: A standardized curriculum for medical students completing a 4-week radiation oncology clerkship was successfully implemented at 2 institutions. The curriculum was favorably reviewed. As a result of completing the curriculum, medical students felt more comfortable with their specialty decision and better prepared to begin radiation oncology residency.

Golden, Daniel W., E-mail: dgolden@radonc.uchicago.edu [Department of Radiation and Cellular Oncology, University of Chicago Pritzker School of Medicine, Chicago, Illinois (United States); Spektor, Alexander [Department of Radiation Oncology, Brigham and Women's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts (United States); Rudra, Sonali; Ranck, Mark C. [Department of Radiation and Cellular Oncology, University of Chicago Pritzker School of Medicine, Chicago, Illinois (United States); Krishnan, Monica S.; Jimenez, Rachel B.; Viswanathan, Akila N. [Department of Radiation Oncology, Brigham and Women's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts (United States); Koshy, Matthew; Howard, Andrew R.; Chmura, Steven J. [Department of Radiation and Cellular Oncology, University of Chicago Pritzker School of Medicine, Chicago, Illinois (United States)

2014-01-01T23:59:59.000Z

13

American Society for Radiation Oncology (ASTRO) 2012 Workforce Study: The Radiation Oncologists' and Residents' Perspectives  

SciTech Connect

Purpose: The American Society for Radiation Oncology (ASTRO) conducted the 2012 Radiation Oncology Workforce Survey to obtain an up-to-date picture of the workforce, assess its needs and concerns, and identify quality and safety improvement opportunities. The results pertaining to radiation oncologists (ROs) and residents (RORs) are presented here. Methods: The ASTRO Workforce Subcommittee, in collaboration with allied radiation oncology professional societies, conducted a survey study in early 2012. An online survey questionnaire was sent to all segments of the radiation oncology workforce. Respondents who were actively working were included in the analysis. This manuscript describes the data for ROs and RORs. Results: A total of 3618 ROs and 568 RORs were surveyed. The response rate for both groups was 29%, with 1047 RO and 165 ROR responses. Among ROs, the 2 most common racial groups were white (80%) and Asian (15%), and the male-to-female ratio was 2.85 (74% male). The median age of ROs was 51. ROs averaged 253.4 new patient consults in a year and 22.9 on-treatment patients. More than 86% of ROs reported being satisfied or very satisfied overall with their career. Close to half of ROs reported having burnout feelings. There was a trend toward more frequent burnout feelings with increasing numbers of new patient consults. ROs' top concerns were related to documentation, reimbursement, and patients' health insurance coverage. Ninety-five percent of ROs felt confident when implementing new technology. Fifty-one percent of ROs thought that the supply of ROs was balanced with demand, and 33% perceived an oversupply. Conclusions: This study provides a current snapshot of the 2012 radiation oncology physician workforce. There was a predominance of whites and men. Job satisfaction level was high. However a substantial fraction of ROs reported burnout feelings. Perceptions about supply and demand balance were mixed. ROs top concerns reflect areas of attention for the healthcare sector as a whole.

Pohar, Surjeet, E-mail: spohar@iuhealth.org [Indiana University Health East, Indianapolis, Indiana (United States); Fung, Claire Y. [Commonwealth Newburyport Cancer Center, Newburyport, Massachusetts (United States); Hopkins, Shane [William R. Bliss Cancer Center, Ames, Iowa (United States); Miller, Robert [Mayo Clinic, Rochester, Minnesota (United States); Azawi, Samar [VA Veteran Hospital/University of California Irvine, Newport Beach, California (United States); Arnone, Anna; Patton, Caroline [ASTRO, Fairfax, Virginia (United States); Olsen, Christine [Massachusetts General Hospital, Boston, Massachusetts (United States)

2013-12-01T23:59:59.000Z

14

Quantitative Assessment of Workload and Stressors in Clinical Radiation Oncology  

SciTech Connect

Purpose: Workload level and sources of stressors have been implicated as sources of error in multiple settings. We assessed workload levels and sources of stressors among radiation oncology professionals. Furthermore, we explored the potential association between workload and the frequency of reported radiotherapy incidents by the World Health Organization (WHO). Methods and Materials: Data collection was aimed at various tasks performed by 21 study participants from different radiation oncology professional subgroups (simulation therapists, radiation therapists, physicists, dosimetrists, and physicians). Workload was assessed using National Aeronautics and Space Administration Task-Load Index (NASA TLX). Sources of stressors were quantified using observational methods and segregated using a standard taxonomy. Comparisons between professional subgroups and tasks were made using analysis of variance ANOVA, multivariate ANOVA, and Duncan test. An association between workload levels (NASA TLX) and the frequency of radiotherapy incidents (WHO incidents) was explored (Pearson correlation test). Results: A total of 173 workload assessments were obtained. Overall, simulation therapists had relatively low workloads (NASA TLX range, 30-36), and physicists had relatively high workloads (NASA TLX range, 51-63). NASA TLX scores for physicians, radiation therapists, and dosimetrists ranged from 40-52. There was marked intertask/professional subgroup variation (P<.0001). Mental demand (P<.001), physical demand (P=.001), and effort (P=.006) significantly differed among professional subgroups. Typically, there were 3-5 stressors per cycle of analyzed tasks with the following distribution: interruptions (41.4%), time factors (17%), technical factors (13.6%), teamwork issues (11.6%), patient factors (9.0%), and environmental factors (7.4%). A positive association between workload and frequency of reported radiotherapy incidents by the WHO was found (r = 0.87, P value=.045). Conclusions: Workload level and sources of stressors vary among professional subgroups. Understanding the factors that influence these findings can guide adjustments to the workflow procedures, physical layout, and/or communication protocols to enhance safety. Additional evaluations are needed in order to better understand if these findings are systemic.

Mazur, Lukasz M., E-mail: lukasz_mazur@ncsu.edu [Department of Radiation Oncology, University of North Carolina, Chapel Hill, North Carolina (United States); Industrial Extension Service, North Carolina State University, Raleigh, North Carolina (United States); Biomedical Engineering, North Carolina State University, Raleigh, North Carolina (United States); Mosaly, Prithima R. [Industrial Extension Service, North Carolina State University, Raleigh, North Carolina (United States)] [Industrial Extension Service, North Carolina State University, Raleigh, North Carolina (United States); Jackson, Marianne; Chang, Sha X.; Burkhardt, Katharin Deschesne; Adams, Robert D.; Jones, Ellen L.; Hoyle, Lesley [Department of Radiation Oncology, University of North Carolina, Chapel Hill, North Carolina (United States)] [Department of Radiation Oncology, University of North Carolina, Chapel Hill, North Carolina (United States); Xu, Jing [Industrial Extension Service, North Carolina State University, Raleigh, North Carolina (United States)] [Industrial Extension Service, North Carolina State University, Raleigh, North Carolina (United States); Rockwell, John; Marks, Lawrence B. [Department of Radiation Oncology, University of North Carolina, Chapel Hill, North Carolina (United States)] [Department of Radiation Oncology, University of North Carolina, Chapel Hill, North Carolina (United States)

2012-08-01T23:59:59.000Z

15

Japanese Structure Survey of Radiation Oncology in 2007 with Special Reference to Designated Cancer Care Hospitals  

Science Journals Connector (OSTI)

The structure of radiation oncology in designated cancer care hospitals in Japan was investigated in terms of equipment, personnel ... of changes in the health care policy in Japan on radiotherapy structure was a...

Hodaka Numasaki; Hitoshi Shibuya; Masamichi Nishio…

2011-03-01T23:59:59.000Z

16

First Author Research Productivity of United States Radiation Oncology Residents: 2002-2007  

SciTech Connect

Purpose: Participation in investigative research is a required element of radiation oncology residency in the United States. Our purpose was to quantify the first author research productivity of recent U.S. radiation oncology residents during their residency training. Methods and Materials: We performed a computer-based search of PubMed and a manual review of the proceedings of the annual meetings of the American Society for Therapeutic Radiology and Oncology to identify all publications and presented abstracts with a radiation oncology resident as the first author between 2002 and 2007. Results: Of 1,098 residents trained at 81 programs, 50% published {>=}1 article (range, 0-9), and 53% presented {>=}1 abstract (range, 0-3) at an American Society for Therapeutic Radiology and Oncology annual meeting. The national average was 1.01 articles published and 1.09 abstracts presented per resident during 4 years of training. Of 678 articles published, 82% represented original research and 18% were review articles. Residents contributed 15% of all abstracts at American Society for Therapeutic Radiology and Oncology annual meetings, and the resident contribution to orally presented abstracts increased from 12% to 21% during the study period. Individuals training at programs with >6 residents produced roughly twice as many articles and abstracts. Holman Research Pathway residents produced double the national average of articles and abstracts. Conclusion: Although variability exists among individuals and among training programs, U.S. radiation oncology residents routinely participate in investigative research suitable for publication or presentation at a scientific meeting. These data provide national research benchmarks that can assist current and future radiation oncology residents and training programs in their self-assessment and research planning.

Morgan, Peter B. [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States)], E-mail: peter.morgan@fccc.edu; Sopka, Dennis M. [Drexel University College of Medicine, Philadelphia, PA (United States); Kathpal, Madeera [Division of Neurosurgery, Philadelphia College of Osteopathic Medicine, Philadelphia, PA (United States); Haynes, Jeffrey C. [Department of Radiation Oncology, Hospital of University of Pennsylvania, Philadelphia, PA (United States); Lally, Brian E.; Li, Linna [Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA (United States)

2009-08-01T23:59:59.000Z

17

An Assessment of the Current US Radiation Oncology Workforce: Methodology and Global Results of the American Society for Radiation Oncology 2012 Workforce Study  

SciTech Connect

Purpose: To determine the characteristics, needs, and concerns of the current radiation oncology workforce, evaluate best practices and opportunities for improving quality and safety, and assess what we can predict about the future workforce. Methods and Materials: An online survey was distributed to 35,204 respondents from all segments of the radiation oncology workforce, including radiation oncologists, residents, medical dosimetrists, radiation therapists, medical physicists, nurse practitioners, nurses, physician assistants, and practice managers/administrators. The survey was disseminated by the American Society for Radiation Oncology (ASTRO) together with specialty societies representing other workforce segments. An overview of the methods and global results is presented in this paper. Results: A total of 6765 completed surveys were received, a response rate of 19%, and the final analysis included 5257 respondents. Three-quarters of the radiation oncologists, residents, and physicists who responded were male, in contrast to the other segments in which two-thirds or more were female. The majority of respondents (58%) indicated they were hospital-based, whereas 40% practiced in a free-standing/satellite clinic and 2% in another setting. Among the practices represented in the survey, 21.5% were academic, 25.2% were hospital, and 53.3% were private. A perceived oversupply of professionals relative to demand was reported by the physicist, dosimetrist, and radiation therapist segments. An undersupply was perceived by physician's assistants, nurse practitioners, and nurses. The supply of radiation oncologists and residents was considered balanced. Conclusions: This survey was unique as it attempted to comprehensively assess the radiation oncology workforce by directly surveying each segment. The results suggest there is potential to improve the diversity of the workforce and optimize the supply of the workforce segments. The survey also provides a benchmark for future studies, as many changes in the healthcare field exert pressure on the workforce.

Vichare, Anushree; Washington, Raynard; Patton, Caroline; Arnone, Anna [ASTRO, Fairfax, Virginia (United States); Olsen, Christine [Massachusetts General Hospital, Boston, Massachusetts, (United States); Fung, Claire Y. [Commonwealth Newburyport Cancer Center, Newburyport, Massachusetts (United States); Hopkins, Shane [William R. Bliss Cancer Center, Ames, Iowa (United States); Pohar, Surjeet, E-mail: spohar@netzero.net [Indiana University Health Cancer Center East, Indiana University, Indianapolis, Indiana (United States)

2013-12-01T23:59:59.000Z

18

Brand Guidelines Northwestern University Feinberg School of Medicine  

E-Print Network (OSTI)

, the repetition of messages and visuals serves to solidify a brand's image. For Feinberg, these messagesBrand Guidelines Northwestern University Feinberg School of Medicine Published February 9, 2010 djfhakjd ExitForwardBack #12;1 Northwestern University Feinberg School of Medicine Brand Guidelines Story

Engman, David M.

19

Current Status and Recommendations for the Future of Research, Teaching, and Testing in the Biological Sciences of Radiation Oncology: Report of the American Society for Radiation Oncology Cancer Biology/Radiation Biology Task Force, Executive Summary  

SciTech Connect

In early 2011, a dialogue was initiated within the Board of Directors (BOD) of the American Society for Radiation Oncology (ASTRO) regarding the future of the basic sciences of the specialty, primarily focused on the current state and potential future direction of basic research within radiation oncology. After consideration of the complexity of the issues involved and the precise nature of the undertaking, in August 2011, the BOD empanelled a Cancer Biology/Radiation Biology Task Force (TF). The TF was charged with developing an accurate snapshot of the current state of basic (preclinical) research in radiation oncology from the perspective of relevance to the modern clinical practice of radiation oncology as well as the education of our trainees and attending physicians in the biological sciences. The TF was further charged with making suggestions as to critical areas of biological basic research investigation that might be most likely to maintain and build further the scientific foundation and vitality of radiation oncology as an independent and vibrant medical specialty. It was not within the scope of service of the TF to consider the quality of ongoing research efforts within the broader radiation oncology space, to presume to consider their future potential, or to discourage in any way the investigators committed to areas of interest other than those targeted. The TF charge specifically precluded consideration of research issues related to technology, physics, or clinical investigations. This document represents an Executive Summary of the Task Force report.

Wallner, Paul E., E-mail: pwallner@theabr.org [21st Century Oncology, LLC, and the American Board of Radiology, Bethesda, Maryland (United States); Anscher, Mitchell S. [Department of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia (United States); Barker, Christopher A. [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Bassetti, Michael [Department of Human Oncology, University of Wisconsin Carbone Cancer Center, Madison, Wisconsin (United States); Bristow, Robert G. [Departments of Radiation Oncology and Medical Biophysics, Princess Margaret Cancer Center/University of Toronto, Toronto, Ontario (Canada); Cha, Yong I. [Department of Radiation Oncology, Norton Cancer Center, Louisville, Kentucky (United States); Dicker, Adam P. [Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania (United States); Formenti, Silvia C. [Department of Radiation Oncology, New York University, New York, New York (United States); Graves, Edward E. [Departments of Radiation Oncology and Radiology, Stanford University, Stanford, California (United States); Hahn, Stephen M. [Department of Radiation Oncology, University of Pennsylvania (United States); Hei, Tom K. [Center for Radiation Research, Columbia University, New York, New York (United States); Kimmelman, Alec C. [Department of Radiation Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts (United States); Kirsch, David G. [Department of Radiation Oncology, Duke University, Durham, North Carolina (United States); Kozak, Kevin R. [Department of Human Oncology, University of Wisconsin (United States); Lawrence, Theodore S. [Department of Radiation Oncology, University of Michigan (United States); Marples, Brian [Department of Radiation Oncology, Oakland University, Oakland, California (United States); and others

2014-01-01T23:59:59.000Z

20

Comparing disease expression across species: an examination of radiation and species specific disease expression in Mus musculus and Peromyscus leucopus  

NLE Websites -- All DOE Office Websites (Extended Search)

disease expression across species: an examination of radiation and species specific disease expression across species: an examination of radiation and species specific disease expression in Mus musculus and Peromyscus leucopus William Liu 1 , Benjamin Haley 1 , Mary J. Kwasny 2 , Tatjana Paunesku 1 , Gayle Woloschak 1 1. Department of Radiation Oncology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611 2. Department of Preventative Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611 From 1969 to 1992, the Janus program at Argonne National Laboratory performed a large series of radiobiology experiments, examining the effects of varying doses of neutron and gamma radiation on two disparate species of mice, Mus musculus and Peromyscus leucopus. Much of this data has since been digitized and made freely accessible online. This study aims to revisit

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21

Oral tissue changes of radiation-oncology and their management  

SciTech Connect

The cytologic effects of radiation therapy involve all tissues and most significantly bone within the treated area. Of greatest concern is the permanence of the compromised healing and resistance to infection of the irradiated tissues. Those dental procedures that do not cause tissue trauma are considered nonrisk. Any procedure that traumatizes previously irradiated tissues can exceed the healing potential of the compromised tissue and frequently results in an uncontrollable necrosis. The adequate utilization of hyperbaric oxygen therapy has been shown to be 95% effective in preventing osteoradionecrosis in postirradiated tissues. 9 references.

Fleming, T.J. (Univ. of Texas M.D. Anderson Cancer Center, Houston (USA))

1990-04-01T23:59:59.000Z

22

Adjuvant and Salvage Radiation Therapy After Prostatectomy: American Society for Radiation Oncology/American Urological Association Guidelines  

SciTech Connect

Purpose: The purpose of this guideline was to provide a clinical framework for the use of radiation therapy after radical prostatectomy as adjuvant or salvage therapy. Methods and Materials: A systematic literature review using PubMed, Embase, and Cochrane database was conducted to identify peer-reviewed publications relevant to the use of radiation therapy after prostatectomy. The review yielded 294 articles; these publications were used to create the evidence-based guideline statements. Additional guidance is provided as Clinical Principles when insufficient evidence existed. Results: Guideline statements are provided for patient counseling, use of radiation therapy in the adjuvant and salvage contexts, defining biochemical recurrence, and conducting a restaging evaluation. Conclusions: Physicians should offer adjuvant radiation therapy to patients with adverse pathologic findings at prostatectomy (ie, seminal vesicle invastion, positive surgical margins, extraprostatic extension) and salvage radiation therapy to patients with prostate-specific antigen (PSA) or local recurrence after prostatectomy in whom there is no evidence of distant metastatic disease. The offer of radiation therapy should be made in the context of a thoughtful discussion of possible short- and long-term side effects of radiation therapy as well as the potential benefits of preventing recurrence. The decision to administer radiation therapy should be made by the patient and the multidisciplinary treatment team with full consideration of the patient's history, values, preferences, quality of life, and functional status. The American Society for Radiation Oncology and American Urological Association websites show this guideline in its entirety, including the full literature review.

Valicenti, Richard K., E-mail: Richard.valicenti@ucdmc.ucdavis.edu [Department of Radiation Oncology, University of California, Davis School of Medicine, Davis, California (United States); Thompson, Ian [Department of Urology, University of Texas Health Science Center at San Antonio, San Antonio, Texas (United States); Albertsen, Peter [Division of Urology, University of Connecticut Health Center, Farmington, Connecticut (United States); Davis, Brian J. [Department of Radiation Oncology, Mayo Medical School, Rochester, Minnesota (United States); Goldenberg, S. Larry [Department of Urologic Sciences, University of British Columbia, Vancouver, British Columbia (Canada); Wolf, J. Stuart [Department of Urology, University of Michigan, Ann Arbor, Michigan (United States); Sartor, Oliver [Department of Medicine and Urology, Tulane Medical School, New Orleans, Louisiana (United States); Klein, Eric [Glickman Urological Kidney Institute, Cleveland Clinic, Cleveland, Ohio (United States); Hahn, Carol [Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina (United States); Michalski, Jeff [Department of Radiation Oncology, Washington University School of Medicine, St. Louis, Missouri (United States); Roach, Mack [Department of Radiation Oncology, University of California, San Francisco, San Francisco, California (United States); Faraday, Martha M. [Four Oaks, Inc (United States)

2013-08-01T23:59:59.000Z

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Cumulative radiation dose estimates from medical imaging in paediatric patients with non-oncologic chronic illnesses. A systematic review  

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Abstract Paediatric patients with non-oncologic chronic illnesses often require ongoing care that may result in repeated imaging and exposure to ionizing radiation from both diagnostic and interventional procedures. In this study the scientific literature on cumulative effective dose (CED) of radiation accrued from medical imaging among specific cohorts of paediatric, non-oncologic chronic patients (inflammatory bowel disease, cystic fibrosis, congenital heart disease, shunt-treated hydrocephalus, hemophilia, spinal dysraphism) was systematically reviewed. We conducted PubMed/Medline, Scopus and EMBASE searches of peer-reviewed papers on CED from diagnostic and therapeutic radiological examinations. No time restriction was introduced in the search. Only studies reporting \\{CEDs\\} accrued for a period >1 year were included. We found that the annual CED was relatively low (3–20 mSv/year) in Crohn's patients. This extra yearly radiation exposure accrues over the lifetime and can reach high values (>100 mSv) in selected cohorts of paediatric chronic patients.

Marco Brambilla; Andreana De Mauri; Domenico Lizio; Lucia Leva; Alessandro Carriero; Clara Carpeggiani; Eugenio Picano

2014-01-01T23:59:59.000Z

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Validation and Simplification of the Radiation Therapy Oncology Group Recursive Partitioning Analysis Classification for Glioblastoma  

SciTech Connect

Purpose: Previous recursive partitioning analysis (RPA) of patients with malignant glioma (glioblastoma multiforme [GBM] and anaplastic astrocytoma [AA]) produced six prognostic groups (I-VI) classified by six factors. We sought here to determine whether the classification for GBM could be improved by using an updated Radiation Therapy Oncology Group (RTOG) GBM database excluding AA and by considering additional baseline variables. Methods and Materials: The new analysis considered 42 baseline variables and 1,672 GBM patients from the expanded RTOG glioma database. Patients receiving radiation only were excluded such that all patients received radiation+carmustine. 'Radiation dose received' was replaced with 'radiation dose assigned.' The new RPA models were compared with the original model by applying them to a test dataset comprising 488 patients from six other RTOG trials. Fitness of the original and new models was evaluated using explained variation. Results: The original RPA model explained more variations in survival in the test dataset than did the new models (20% vs. 15%) and was therefore chosen for further analysis. It was reduced by combining Classes V and VI to produce three prognostic classes (Classes III, IV, and V+VI), as Classes V and VI had indistinguishable survival in the test dataset. The simplified model did not further improve performance (explained variation 18% vs. 20%) but is easier to apply because it involves only four variables: age, performance status, extent of resection, and neurologic function. Applying this simplified model to the updated GBM database resulted in three distinct classes with median survival times of 17.1, 11.2, and 7.5 months for Classes III, IV, and V+VI, respectively. Conclusions: The final model, the simplified original RPA model combining Classes V and VI, resulted in three distinct prognostic groups defined by age, performance status, extent of resection, and neurologic function. This classification will be used in future RTOG GBM trials.

Li Jing [University of Texas MD Anderson Cancer Center, Houston, TX (United States); Wang Meihua; Won, Minhee [RTOG Statistical Center, Philadelphia, PA (United States); Shaw, Edward G. [Wake Forest University School of Medicine, Winston-Salem, NC (United States); Coughlin, Christopher [Federal Bureau of Prisons, Butner, NC (United States); Curran, Walter J. [Emory Clinic, Atlanta, GA (United States); Mehta, Minesh P., E-mail: mehta@humonc.wisc.edu [University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI (United States)

2011-11-01T23:59:59.000Z

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An Evaluation of Departmental Radiation Oncology Incident Reports: Anticipating a National Reporting System  

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Purpose Systems to ensure patient safety are of critical importance. The electronic incident reporting systems (IRS) of 2 large academic radiation oncology departments were evaluated for events that may be suitable for submission to a national reporting system (NRS). Methods and Materials All events recorded in the combined IRS were evaluated from 2007 through 2010. Incidents were graded for potential severity using the validated French Nuclear Safety Authority (ASN) 5-point scale. These incidents were categorized into 7 groups: (1) human error, (2) software error, (3) hardware error, (4) error in communication between 2 humans, (5) error at the human-software interface, (6) error at the software-hardware interface, and (7) error at the human-hardware interface. Results Between the 2 systems, 4407 incidents were reported. Of these events, 1507 (34%) were considered to have the potential for clinical consequences. Of these 1507 events, 149 (10%) were rated as having a potential severity of ?2. Of these 149 events, the committee determined that 79 (53%) of these events would be submittable to a NRS of which the majority was related to human error or to the human-software interface. Conclusions A significant number of incidents were identified in this analysis. The majority of events in this study were related to human error and to the human-software interface, further supporting the need for a NRS to facilitate field-wide learning and system improvement.

Stephanie A. Terezakis; Kendra M. Harris; Eric Ford; Jeff Michalski; Theodore DeWeese; Lakshmi Santanam; Sasa Mutic; Hiram Gay

2013-01-01T23:59:59.000Z

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Japanese Structure Survey of Radiation Oncology in 2005 Based on Institutional Stratification of Patterns of Care Study  

SciTech Connect

Purpose: To evaluate the structure of radiation oncology in Japan in terms of equipment, personnel, patient load, and geographic distribution to identify and improve any deficiencies. Methods and Materials: A questionnaire-based national structure survey was conducted between March 2006 and February 2007 by the Japanese Society of Therapeutic Radiology and Oncology. These data were analyzed in terms of the institutional stratification of the Patterns of Care Study. Results: The total numbers of new cancer patients and total cancer patients (new and repeat) treated with radiotherapy in 2005 were estimated at approximately 162,000 and 198,000, respectively. In actual use were 765 linear accelerators, 11 telecobalt machines, 48 GammaKnife machines, 64 {sup 60}Co remote-controlled after-loading systems, and 119 {sup 192}Ir remote-controlled after-loading systems. The linear accelerator systems used dual-energy function in 498 systems (65%), three-dimensional conformal radiotherapy in 462 (60%), and intensity-modulated radiotherapy in 170 (22%). There were 426 Japanese Society of Therapeutic Radiology and Oncology-certified radiation oncologists, 774 full-time equivalent radiation oncologists, 117 medical physicists, and 1,635 radiation therapists. Geographically, a significant variation was found in the use of radiotherapy, from 0.9 to 2.1 patients/1,000 population. The annual patient load/FTE radiation oncologist was 247, exceeding the Blue Book guidelines level. Patterns of Care Study stratification can clearly discriminate the maturity of structures according to their academic nature and caseload. Conclusions: The Japanese structure has clearly improved during the past 15 years in terms of equipment and its use, although the shortage of manpower and variations in maturity disclosed by this Patterns of Care Study stratification remain problematic. These constitute the targets for nationwide improvement in quality assurance and quality control.

Teshima, Teruki [Department of Medical Physics and Engineering, Osaka University Graduate School of Medicine, Suita, Osaka (Japan)], E-mail: teshima@sahs.med.osaka-u.ac.jp; Numasaki, Hodaka [Department of Medical Physics and Engineering, Osaka University Graduate School of Medicine, Suita, Osaka (Japan); Shibuya, Hitoshi [Department of Radiology, Tokyo Dental and Medical University, Tokyo (Japan); Nishio, Masamichi [Department of Radiology, National Hospital Organization Hokkaido Cancer Center, Sapporo, Hokkaido (Japan); Ikeda, Hiroshi [Division of Radiation Oncology, National Cancer Center, Tokyo (Japan); Ito, Hisao [Department of Radiology, Chiba University Graduate School of Medicine, Chiba (Japan); Sekiguchi, Kenji [Department of Radiation Oncology, St. Luke's International Hospital, Tokyo (Japan); Kamikonya, Norihiko [Department of Radiology, Hyogo College of Medicine, Nishinomiya, Hyogo (Japan); Koizumi, Masahiko [Department of Radiological Technology, Fujita Health University School of Health Sciences, Nagoya, Aichi (Japan); Tago, Masao [Department of Radiology, University of Tokyo Hospital, Tokyo (Japan); Nagata, Yasushi [Department of Radiation Oncology and Image-Applied Therapy, Kyoto University Graduate School of Medicine, Kyoto (Japan); Masaki, Hidekazu [Department of Radiology, National Center for Child Health and Development, Tokyo (Japan); Nishimura, Tetsuo [Division of Radiation Oncology, Shizuoka Cancer Center, Shizuoka (Japan); Yamada, Shogo [Tohoku University Hospital Cancer Center, Sendai (Japan)

2008-09-01T23:59:59.000Z

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Japanese Structure Survey of Radiation Oncology in 2007 Based on Institutional Stratification of Patterns of Care Study  

SciTech Connect

Purpose: To evaluate the ongoing structure of radiation oncology in Japan in terms of equipment, personnel, patient load, and geographic distribution to identify and improve any deficiencies. Methods and Materials: A questionnaire-based national structure survey was conducted from March to December 2008 by the Japanese Society of Therapeutic Radiology and Oncology (JASTRO). These data were analyzed in terms of the institutional stratification of the Patterns of Care Study. Results: The total numbers of new cancer patients and total cancer patients (new and repeat) treated with radiation in 2007 were estimated at 181,000 and 218,000, respectively. There were 807 linear accelerator, 15 telecobalt, 46 Gamma Knife, 45 {sup 60}Co remote-controlled after-loading, and 123 {sup 192}Ir remote-controlled after-loading systems in actual use. The linear accelerator systems used dual-energy function in 539 units (66.8%), three-dimensional conformal radiation therapy in 555 (68.8%), and intensity-modulated radiation therapy in 235 (29.1%). There were 477 JASTRO-certified radiation oncologists, 826.3 full-time equivalent (FTE) radiation oncologists, 68.4 FTE medical physicists, and 1,634 FTE radiation therapists. The number of interstitial radiotherapy (RT) administrations for prostate, stereotactic body radiotherapy, and intensity-modulated radiation therapy increased significantly. Patterns of Care Study stratification can clearly identify the maturity of structures based on their academic nature and caseload. Geographically, the more JASTRO-certified physicians there were in a given area, the more RT tended to be used for cancer patients. Conclusions: The Japanese structure has clearly improved during the past 17 years in terms of equipment and its use, although a shortage of personnel and variations in maturity disclosed by Patterns of Care Study stratification were still problematic in 2007.

Teshima, Teruki, E-mail: teshima@sahs.med.osaka-u.ac.j [Department of Medical Physics and Engineering, Osaka University Graduate School of Medicine, Suita (Japan); Numasaki, Hodaka [Department of Medical Physics and Engineering, Osaka University Graduate School of Medicine, Suita (Japan); Shibuya, Hitoshi [Department of Radiology, Tokyo Dental and Medical University, Tokyo (Japan); Nishio, Masamichi [Department of Radiology, National Hospital Organization Hokkaido Cancer Center, Sapporo (Japan); Ikeda, Hiroshi [Department of Radiation Oncology, Sakai Municipal Hospital, Sakai (Japan); Sekiguchi, Kenji [Department of Radiation Oncology, St. Luke's International Hospital, Tokyo (Japan); Kamikonya, Norihiko [Department of Radiology, Hyogo College of Medicine, Nishinomiya (Japan); Koizumi, Masahiko [Oncology Center, Osaka University Hospital, Suita (Japan); Tago, Masao [Department of Radiology, Toho University Omori Medical Center, Tokyo (Japan); Ando, Yutaka [Department of Medical Informatics, Heavy Ion Medical Center, National Institute of Radiological Sciences, Chiba (Japan); Tsukamoto, Nobuhito [Department of Radiation Oncology, Saitama Medical University International Medical Center, Saitama (Japan); Terahara, Atsuro [Department of Radiology, University of Tokyo Hospital, Tokyo (Japan); Nakamura, Katsumasa [Department of Radiology, Kyushu University Hospital at Beppu, Oita (Japan); Mitsumori, Michihide [Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine Kyoto University, Kyoto (Japan); Nishimura, Tetsuo [Division of Radiation Oncology, Shizuoka Cancer Center, Shizuoka (Japan); Hareyama, Masato [Department of Radiology, Sapporo Medical University, Hokkaido (Japan)

2010-12-01T23:59:59.000Z

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Insufficiency Fractures After Pelvic Radiation Therapy for Uterine Cervical Cancer: An Analysis of Subjects in a Prospective Multi-institutional Trial, and Cooperative Study of the Japan Radiation Oncology Group (JAROG) and Japanese Radiation Oncology Study Group (JROSG)  

SciTech Connect

Purpose: To investigate pelvic insufficiency fractures (IF) after definitive pelvic radiation therapy for early-stage uterine cervical cancer, by analyzing subjects of a prospective, multi-institutional study. Materials and Methods: Between September 2004 and July 2007, 59 eligible patients were analyzed. The median age was 73 years (range, 37-84 years). The International Federation of Gynecologic Oncology and Obstetrics stages were Ib1 in 35, IIa in 12, and IIb in 12 patients. Patients were treated with the constant method, which consisted of whole-pelvic external-beam radiation therapy of 50 Gy/25 fractions and high-dose-rate intracavitary brachytherapy of 24 Gy/4 fractions without chemotherapy. After radiation therapy the patients were evaluated by both pelvic CT and pelvic MRI at 3, 6, 12, 18, and 24 months. Diagnosis of IF was made when the patients had both CT and MRI findings, neither recurrent tumor lesions nor traumatic histories. The CT findings of IF were defined as fracture lines or sclerotic linear changes in the bones, and MRI findings of IF were defined as signal intensity changes in the bones, both on T1- and T2-weighted images. Results: The median follow-up was 24 months. The 2-year pelvic IF cumulative occurrence rate was 36.9% (21 patients). Using Common Terminology Criteria for Adverse Events version 3.0, grade 1, 2, and 3 IF were seen in 12 (21%), 6 (10%), and 3 patients (5%), respectively. Sixteen patients had multiple fractures, so IF were identified at 44 sites. The pelvic IF were frequently seen at the sacroileal joints (32 sites, 72%). Nine patients complained of pain. All patients' pains were palliated by rest or non-narcotic analgesic drugs. Higher age (>70 years) and low body weight (<50 kg) were thought to be risk factors for pelvic IF (P=.007 and P=.013, Cox hazard test). Conclusions: Cervical cancer patients with higher age and low body weight may be at some risk for the development of pelvic IF after pelvic radiation therapy.

Tokumaru, Sunao, E-mail: tokumaru@cc.saga-u.ac.jp [Department of Heavy Particle Therapy and Radiation Oncology, Saga University, Saga (Japan)] [Department of Heavy Particle Therapy and Radiation Oncology, Saga University, Saga (Japan); Toita, Takafumi [Department of Radiology, Graduate School of Medical Science, University of the Ryukyus, Okinawa (Japan)] [Department of Radiology, Graduate School of Medical Science, University of the Ryukyus, Okinawa (Japan); Oguchi, Masahiko [Radiation Oncology Department, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo (Japan)] [Radiation Oncology Department, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo (Japan); Ohno, Tatsuya [Gunma University Heavy Ion Medical Center, Maebashi (Japan)] [Gunma University Heavy Ion Medical Center, Maebashi (Japan); Kato, Shingo [Department of Radiation Oncology, Saitama Medical University, International Medical Center, Saitama (Japan)] [Department of Radiation Oncology, Saitama Medical University, International Medical Center, Saitama (Japan); Niibe, Yuzuru [Department of Radiology, School of Medicine, Kitasato University, Sagamihara (Japan)] [Department of Radiology, School of Medicine, Kitasato University, Sagamihara (Japan); Kazumoto, Tomoko [Department of Radiology, Saitama Cancer Center, Saitama (Japan)] [Department of Radiology, Saitama Cancer Center, Saitama (Japan); Kodaira, Takeshi [Department of Radiation Oncology, Aichi Cancer Center, Nagoya (Japan)] [Department of Radiation Oncology, Aichi Cancer Center, Nagoya (Japan); Kataoka, Masaaki [Department of Radiology, National Shikoku Cancer Center, Matsuyama (Japan)] [Department of Radiology, National Shikoku Cancer Center, Matsuyama (Japan); Shikama, Naoto [Department of Radiation Oncology, Saitama Medical University, International Medical Center, Saitama (Japan)] [Department of Radiation Oncology, Saitama Medical University, International Medical Center, Saitama (Japan); Kenjo, Masahiro [Department of Radiation Oncology, Graduate School of Medical Science, Hiroshima University, Hiroshima (Japan)] [Department of Radiation Oncology, Graduate School of Medical Science, Hiroshima University, Hiroshima (Japan); Yamauchi, Chikako [Department of Radiation Oncology, Shiga Medical Center for Adults, Moriyama (Japan)] [Department of Radiation Oncology, Shiga Medical Center for Adults, Moriyama (Japan); Suzuki, Osamu [Department of Radiation Oncology, Osaka Medical Center for Cancer, Osaka (Japan)] [Department of Radiation Oncology, Osaka Medical Center for Cancer, Osaka (Japan); Sakurai, Hideyuki [Proton Medical Research Center and Tsukuba University, Tuskuba (Japan)] [Proton Medical Research Center and Tsukuba University, Tuskuba (Japan); Teshima, Teruki [Department of Medical Physics and Engineering, Graduate School of Medicine, Osaka University, Suita (Japan)] [Department of Medical Physics and Engineering, Graduate School of Medicine, Osaka University, Suita (Japan); Kagami, Yoshikazu [Department of Radiology, Showa University School of Medicine, Tokyo (Japan)] [Department of Radiology, Showa University School of Medicine, Tokyo (Japan); Nakano, Takashi [Department of Radiation Oncology, Gunma University, Graduate School of Medicine, Maebashi (Japan)] [Department of Radiation Oncology, Gunma University, Graduate School of Medicine, Maebashi (Japan); Hiraoka, Masahiro [Department of Radiation Oncology and Image-applied Therapy, Kyoto University, Graduate School of Medicine, Kyoto (Japan)] [Department of Radiation Oncology and Image-applied Therapy, Kyoto University, Graduate School of Medicine, Kyoto (Japan); and others

2012-10-01T23:59:59.000Z

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Patterns of Radiotherapy Practice for Pancreatic Cancer in Japan: Results of the Japanese Radiation Oncology Study Group (JROSG) Survey  

Science Journals Connector (OSTI)

Purpose To determine the patterns of radiotherapy practice for pancreatic cancer in Japan. Methods and Materials A questionnaire-based national survey of radiotherapy for pancreatic cancer treated between 2000 and 2006 was conducted by the Japanese Radiation Oncology Study Group (JROSG). Detailed information on 870 patients from 34 radiation oncology institutions was accumulated. Results The median age of all patients was 64 years (range, 36–88), and 80.2% of the patients had good performance status. More than 85% of patients had clinical Stage T3-T4 disease, and 68.9% of patients had unresectable disease at diagnosis. Concerning radiotherapy (RT), 49.8% of patients were treated with radical external beam RT (EBRT) (median dose, 50.4 Gy), 44.4% of patients were treated with intraoperative RT (median dose, 25 Gy) with or without EBRT (median dose, 45 Gy), and 5.9% of patients were treated with postoperative radiotherapy (median dose, 50 Gy). The treatment field consisted of the primary tumor (bed) only in 55.6% of the patients. Computed tomography-based treatment planning and conformal RT was used in 93.1% and 83.1% of the patients treated with EBRT, respectively. Chemotherapy was used for 691 patients (79.4%; before RT for 66 patients; during RT for 531; and after RT for 364). Gemcitabine was the most frequently used drug, followed by 5-fluorouracil. Conclusion This study describes the general patterns of RT practice for pancreatic cancer in Japan. Most patients had advanced unresectable disease, and radical EBRT, as well as intraoperative RT with or without EBRT, was frequently used. Chemotherapy with gemcitabine was commonly used in conjunction with RT during the survey period.

Kazuhiko Ogawa; Yoshinori Ito; Katsuyuki Karasawa; Yoshihiro Ogawa; Hiroshi Onishi; Tomoko Kazumoto; Keiko Shibuya; Hitoshi Shibuya; Yoshishige Okuno; Shigeo Nishino; Etsuyo Ogo; Nobue Uchida; Kumiko Karasawa; Kenji Nemoto; Yasumasa Nishimura

2010-01-01T23:59:59.000Z

30

Patterns of Radiotherapy Practice for Pancreatic Cancer in Japan: Results of the Japanese Radiation Oncology Study Group (JROSG) Survey  

SciTech Connect

Purpose: To determine the patterns of radiotherapy practice for pancreatic cancer in Japan. Methods and Materials: A questionnaire-based national survey of radiotherapy for pancreatic cancer treated between 2000 and 2006 was conducted by the Japanese Radiation Oncology Study Group (JROSG). Detailed information on 870 patients from 34 radiation oncology institutions was accumulated. Results: The median age of all patients was 64 years (range, 36-88), and 80.2% of the patients had good performance status. More than 85% of patients had clinical Stage T3-T4 disease, and 68.9% of patients had unresectable disease at diagnosis. Concerning radiotherapy (RT), 49.8% of patients were treated with radical external beam RT (EBRT) (median dose, 50.4 Gy), 44.4% of patients were treated with intraoperative RT (median dose, 25 Gy) with or without EBRT (median dose, 45 Gy), and 5.9% of patients were treated with postoperative radiotherapy (median dose, 50 Gy). The treatment field consisted of the primary tumor (bed) only in 55.6% of the patients. Computed tomography-based treatment planning and conformal RT was used in 93.1% and 83.1% of the patients treated with EBRT, respectively. Chemotherapy was used for 691 patients (79.4%; before RT for 66 patients; during RT for 531; and after RT for 364). Gemcitabine was the most frequently used drug, followed by 5-fluorouracil. Conclusion: This study describes the general patterns of RT practice for pancreatic cancer in Japan. Most patients had advanced unresectable disease, and radical EBRT, as well as intraoperative RT with or without EBRT, was frequently used. Chemotherapy with gemcitabine was commonly used in conjunction with RT during the survey period.

Ogawa, Kazuhiko, E-mail: kogawa@med.u-ryukyu.ac.j [Department of Radiology, University of the Ryukyus, Okinawa (Japan); Ito, Yoshinori [Department of Radiation Oncology, National Cancer Center, Tokyo (Japan); Karasawa, Katsuyuki [Department of Radiation Oncology, Tokyo Metropolitan Komagome Hospital, Tokyo (Japan); Ogawa, Yoshihiro [Department of Radiation Oncology, Tohoku University, Sendai (Japan); Onishi, Hiroshi [Department of Radiology, Yamanashi University, Yamanashi (Japan); Kazumoto, Tomoko [Department of Radiation Oncology, Saitama Cancer Center, Saitama (Japan); Shibuya, Keiko [Department of Radiation Oncology and Image-Applied Therapy, Kyoto University, Kyoto (Japan); Shibuya, Hitoshi [Department of Radiology, Tokyo Medical and Dental University, Tokyo (Japan); Okuno, Yoshishige [Department of Radiation Oncology, Kobe City Medical Center General Hospital, Kobe (Japan); Nishino, Shigeo [Department of Radiation Oncology, Sapporo Kosei General Hospital, Sapporo (Japan); Ogo, Etsuyo [Department of Radiology, Kurume University, Kurume (Japan); Uchida, Nobue [Department of Radiation Oncology, Shimane Medical University, Shimane (Japan); Karasawa, Kumiko [Department of Radiation Oncology, Juntendo University, Tokyo (Japan); Nemoto, Kenji [Department of Radiation Oncology, Yamagata University, Yamagata (Japan); Nishimura, Yasumasa [Department of Radiation Oncology, Kinki University School of Medicine, Osaka (Japan)

2010-07-01T23:59:59.000Z

31

Quality Control Quantification (QCQ): A Tool to Measure the Value of Quality Control Checks in Radiation Oncology  

SciTech Connect

Purpose: To quantify the error-detection effectiveness of commonly used quality control (QC) measures. Methods: We analyzed incidents from 2007-2010 logged into a voluntary in-house, electronic incident learning systems at 2 academic radiation oncology clinics. None of the incidents resulted in patient harm. Each incident was graded for potential severity using the French Nuclear Safety Authority scoring scale; high potential severity incidents (score >3) were considered, along with a subset of 30 randomly chosen low severity incidents. Each report was evaluated to identify which of 15 common QC checks could have detected it. The effectiveness was calculated, defined as the percentage of incidents that each QC measure could detect, both for individual QC checks and for combinations of checks. Results: In total, 4407 incidents were reported, 292 of which had high-potential severity. High- and low-severity incidents were detectable by 4.0 {+-} 2.3 (mean {+-} SD) and 2.6 {+-} 1.4 QC checks, respectively (P<.001). All individual checks were less than 50% sensitive with the exception of pretreatment plan review by a physicist (63%). An effectiveness of 97% was achieved with 7 checks used in combination and was not further improved with more checks. The combination of checks with the highest effectiveness includes physics plan review, physician plan review, Electronic Portal Imaging Device-based in vivo portal dosimetry, radiation therapist timeout, weekly physics chart check, the use of checklists, port films, and source-to-skin distance checks. Some commonly used QC checks such as pretreatment intensity modulated radiation therapy QA do not substantially add to the ability to detect errors in these data. Conclusions: The effectiveness of QC measures in radiation oncology depends sensitively on which checks are used and in which combinations. A small percentage of errors cannot be detected by any of the standard formal QC checks currently in broad use, suggesting that further improvements are needed. These data require confirmation with a broader incident-reporting database.

Ford, Eric C., E-mail: eford@uw.edu [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, Maryland (United States); Terezakis, Stephanie; Souranis, Annette; Harris, Kendra [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, Maryland (United States)] [Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, Maryland (United States); Gay, Hiram; Mutic, Sasa [Department of Radiation Oncology, Washington University, St. Louis, Missouri (United States)] [Department of Radiation Oncology, Washington University, St. Louis, Missouri (United States)

2012-11-01T23:59:59.000Z

32

Results of the 2012-2013 Association of Residents in Radiation Oncology (ARRO) Job Search and Career Planning Survey of Graduating Residents in the United States  

SciTech Connect

Purpose/Objective(s): To determine the timeline used by postgraduate year (PGY)-5 radiation oncology residents during the job application process and the factors most important to them when deciding on a first job. Methods and Materials: In 2012 and 2013, the Association of Residents in Radiation Oncology conducted a nationwide electronic survey of PGY-5 radiation oncology residents in the United States during the final 2 months of their training. Descriptive statistics are reported. In addition, subgroup analysis was performed. Results: Surveys were completed by 180 of 314 residents contacted. The median time to start networking for the purpose of employment was January PGY-4; to start contacting practices, complete and upload a curriculum vitae to a job search website, and use the American Society of Radiation Oncology Career Center was June PGY-4; to obtain letters of recommendation was July PGY-5; to start interviewing was August PGY-5; to finish interviewing was December PGY-5; and to accept a contract was January PGY-5. Those applying for a community position began interviewing at an earlier average time than did those applying for an academic position (P=.04). The most important factors to residents when they evaluated job offers included (in order from most to least important) a collegial environment, geographic location, emphasis on best patient care, quality of support staff and facility, and multidisciplinary approach to patient care. Factors that were rated significantly different between subgroups based on the type of position applied for included adequate mentoring, dedicated research time, access to clinical trials, amount of time it takes to become a partner, geographic location, size of group, starting salary, and amount of vacation and days off. Conclusions: The residents' perspective on the job application process over 2 years is documented to provide a resource for current and future residents and employers to use.

Mattes, Malcolm D., E-mail: mdm9007@nyp.org [Department of Radiation Oncology, New York Methodist Hospital, Brooklyn, New York (United States); Kharofa, Jordan [Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin (United States); Zeidan, Youssef H. [Department of Radiation Oncology, Stanford University, Stanford, California (United States); Tung, Kaity [Department of Radiation Oncology, New York Methodist Hospital, Brooklyn, New York (United States); Gondi, Vinai [Department of Radiation Oncology, University of Wisconsin Comprehensive Cancer Center, Madison, Wisconsin (United States); Department of Radiation Oncology, Central Dupage Hospital Cancer Center, Warrenville, Illinois (United States); Golden, Daniel W. [Department of Radiation Oncology, Pritzker School of Medicine, University of Chicago, Chicago, Illinois (United States)

2014-01-01T23:59:59.000Z

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The Impact of New Technologies on Radiation Oncology Events and Trends in the Past Decade: An Institutional Experience  

SciTech Connect

Purpose: To review the type and frequency of patient events from external-beam radiotherapy over a time period sufficiently long to encompass significant technology changes. Methods and Materials: Ten years of quality assurance records from January 2001 through December 2010 were retrospectively reviewed to determine the frequency of events affecting patient treatment from four radiation oncology process steps: simulation, treatment planning, data entry/transfer, and treatment delivery. Patient events were obtained from manual records and, from May 2007 onward, from an institution-wide database and reporting system. Events were classified according to process step of origination and segregated according to the most frequently observed event types. Events from the institution-wide database were evaluated to determine time trends. Results: The overall event rate was 0.93% per course of treatment, with a downward trend over time led by a decrease in treatment delivery events. The frequency of certain event types, particularly in planning and treatment delivery, changed significantly over the course of the study, reflecting technologic and process changes. Treatments involving some form of manual intervention carried an event risk four times higher than those relying heavily on computer-aided design and delivery. Conclusions: Although the overall event rate was low, areas for improvement were identified, including manual calculations and data entry, late-day treatments, and staff overreliance on computer systems. Reducing the incidence of pretreatment events is of particular importance because these were more likely to occur several times before detection and were associated with larger dosimetric impact. Further improvements in quality assurance systems and reporting are imperative, given the advent of electronic charting, increasing reliance on computer systems, and the potentially severe consequences that can arise from mistakes involving complex intensity-modulated or image-guided treatments.

Hunt, Margie A., E-mail: huntm@mskcc.org [Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Pastrana, Gerri [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States)] [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Amols, Howard I. [Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York (United States)] [Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Killen, Aileen [Quality of Care Initiative, Memorial Sloan-Kettering Cancer Center, New York, New York (United States)] [Quality of Care Initiative, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Alektiar, Kaled [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States)] [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States)

2012-11-15T23:59:59.000Z

34

Factors that Determine Academic Versus Private Practice Career Interest in Radiation Oncology Residents in the United States: Results of a Nationwide Survey  

SciTech Connect

Purpose: To determine what factors US radiation oncology residents consider when choosing academic or nonacademic careers. Methods and Materials: A 20-question online survey was developed and sent to all US radiation oncology residents to assess factors that influence their career interest. Residents were asked to rate their interest in academics (A) versus private practice (PP) on a 0 (strong interest in A) to 100 (strong interest in PP) scale. Responses were classified as A (0-30), undecided (40-60), and PP (70-100). Residents were also asked to rank 10 factors that most strongly influenced their career interest. Results: Three hundred thirty-one responses were collected, of which 264 were complete and form the basis for this analysis. Factors that correlated with interest in A included having a PhD (P=.018), postgraduate year level (P=.0006), research elective time (P=.0003), obtaining grant funding during residency (P=.012), and number of publications before residency (P=.0001), but not number of abstracts accepted in the past year (P=.65) or publications during residency (P=.67). The 3 most influential factors for residents interested in A were: (1) baseline interest before residency; (2) academic role models; and (3) research opportunities during residency. The 3 most influential factors for residents interested in PP were: (1) baseline interest before residency; (2) academic role models; and (3) academic pressure and obligations. Conclusions: Interest in A correlated with postgraduate year level, degree, and research time during residency. Publications before but not during residency correlated with academic interest, and baseline interest was the most influential factor. These data can be used by residency program directors to better understand what influences residents' career interest.

Chang, Daniel T., E-mail: dtchang@stanford.edu [Department of Radiation Oncology, Stanford University, Stanford, California (United States); Shaffer, Jenny L. [Department of Radiation Oncology, Stanford University, Stanford, California (United States); Haffty, Bruce G. [Department of Radiation Oncology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, New Jersey (United States); Wilson, Lynn D. [Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut (United States)

2013-11-01T23:59:59.000Z

35

Phase II study of radiation therapy combined with weekly nedaplatin in locally advanced uterine cervical carcinoma: Kitasato Gynecologic Radiation Oncology Group (KGROG 0501) - an initial analysis  

Science Journals Connector (OSTI)

...of Medicine, Chiba, Japan, The University of...induced by ionizing radiation (IR) and can be repaired...of the character and radiation survival ratio of cancer...Hemagglutinating Virus of Japan envelope vector (HVJ-E...clonogenic assay to evaluate radiation sensitivity. Furthermore...

Yuzuru Niibe; Shimpei Tsunoda; Toshiko Jobo; Yukihiro Hamada; and Kazushige Hayakawa

2007-05-01T23:59:59.000Z

36

Relationship between Radiation Exposure and Risk of Second Primary Cancers among Atomic Bomb Survivors  

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...Welford, Department of Radiation Oncology, Case Western Reserve...case.edu 1 Department of Radiation Oncology, Case Western Reserve...Ohio. 2 Department of Radiation Oncology, Osaka University, Osaka, Japan. 3 School of Applied Sciences...

Christopher I. Li; Nobuo Nishi; Jean A. McDougall; Erin O. Semmens; Hiromi Sugiyama; Midori Soda; Ritsu Sakata; Mikiko Hayashi; Fumiyoshi Kasagi; Akihiko Suyama; Kiyohiko Mabuchi; Scott Davis; Kazunori Kodama; and Kenneth J. Kopecky

2010-09-15T23:59:59.000Z

37

IL12RB2 and ABCA1 Genes Are Associated with Susceptibility to Radiation Dermatitis  

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...University, Tokyo, Japan; 7 Department of Radiation Oncology, Graduate...University, Kumamoto, Japan; 8 Department of Radiation Oncology and Image-Applied...University, Hiroshima, Japan; 10 Department of Radiation Oncology, Kinki University...

Minoru Isomura; Natsuo Oya; Seiji Tachiiri; Yuko Kaneyasu; Yasumasa Nishimura; Tetsuo Akimoto; Masato Hareyama; Tadasi Sugita; Norio Mitsuhashi; Takashi Yamashita; Masahiko Aoki; Heitetsu Sai; Yutaka Hirokawa; Koh-ichi Sakata; Kumiko Karasawa; Akihiro Tomida; Takashi Tsuruo; Yoshio Miki; Tetsuo Noda; and Masahiro Hiraoka

2008-10-15T23:59:59.000Z

38

A Comprehensive Quality Assurance Program for Personnel and Procedures in Radiation Oncology: Value of Voluntary Error Reporting and Checklists  

SciTech Connect

Purpose: This report describes the value of a voluntary error reporting system and the impact of a series of quality assurance (QA) measures including checklists and timeouts on reported error rates in patients receiving radiation therapy. Methods and Materials: A voluntary error reporting system was instituted with the goal of recording errors, analyzing their clinical impact, and guiding the implementation of targeted QA measures. In response to errors committed in relation to treatment of the wrong patient, wrong treatment site, and wrong dose, a novel initiative involving the use of checklists and timeouts for all staff was implemented. The impact of these and other QA initiatives was analyzed. Results: From 2001 to 2011, a total of 256 errors in 139 patients after 284,810 external radiation treatments (0.09% per treatment) were recorded in our voluntary error database. The incidence of errors related to patient/tumor site, treatment planning/data transfer, and patient setup/treatment delivery was 9%, 40.2%, and 50.8%, respectively. The compliance rate for the checklists and timeouts initiative was 97% (P<.001). These and other QA measures resulted in a significant reduction in many categories of errors. The introduction of checklists and timeouts has been successful in eliminating errors related to wrong patient, wrong site, and wrong dose. Conclusions: A comprehensive QA program that regularly monitors staff compliance together with a robust voluntary error reporting system can reduce or eliminate errors that could result in serious patient injury. We recommend the adoption of these relatively simple QA initiatives including the use of checklists and timeouts for all staff to improve the safety of patients undergoing radiation therapy in the modern era.

Kalapurakal, John A., E-mail: j-kalapurakal@northwestern.edu [Department of Radiation Oncology, Northwestern University Feinberg School of Medicine, Chicago, Illinois (United States); Zafirovski, Aleksandar; Smith, Jeffery; Fisher, Paul; Sathiaseelan, Vythialingam [Department of Radiation Oncology, Northwestern University Feinberg School of Medicine, Chicago, Illinois (United States)] [Department of Radiation Oncology, Northwestern University Feinberg School of Medicine, Chicago, Illinois (United States); Barnard, Cynthia [Department of Quality Strategies, Northwestern Memorial Hospital, Chicago, Illinois (United States)] [Department of Quality Strategies, Northwestern Memorial Hospital, Chicago, Illinois (United States); Rademaker, Alfred W. [Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois (United States)] [Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois (United States); Rave, Nick [Department of Physicians Services, Northwestern Memorial Hospital, Chicago, Illinois (United States)] [Department of Physicians Services, Northwestern Memorial Hospital, Chicago, Illinois (United States); Mittal, Bharat B. [Department of Radiation Oncology, Northwestern University Feinberg School of Medicine, Chicago, Illinois (United States)] [Department of Radiation Oncology, Northwestern University Feinberg School of Medicine, Chicago, Illinois (United States)

2013-06-01T23:59:59.000Z

39

TH?D?AUD A?09: An Error Reporting and Tracking Database Tool for Process Improvement in Radiation Oncology  

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Patient and employee safety is a critical concern in radiation therapy (RT). Current QA practices and operation processes in RT are typically developed based on rather prescriptive task group reports and regulatory agency requirements. Typically these programs are not developed with the goal of process optimization and safety but are brute?force efforts to prevent catastrophic errors. Other industries have been developing processes to improve quality and safety of their operations and products since the 1940s. These processes have become quite sophisticated and the result is that numerous industries have much better performance records than healthcare and RT. Recently the National Academy of Engineering and the Institute of Medicine recommended the systematic application of systems engineering approaches for reforming our health care delivery system. The AAPM subsequently formed a task group charged with developing a structured systematic QA program approach for RT based on industrial principles and practices. Optimization of RT processes and implementation of industrial techniques requires the acquisition of data regarding performance statistics and failure or error rates of individual departments. Most facilities do not have the infrastructure to effectively collect and analyze such data. We have developed an efficient and effective process for collecting storing and analyzing the failure rate data in individual RT facilities that will support process improvement in patient care and safety. The process is based on a web?based tool for reporting events. The tool is designed so individual events can be reported in as little as two minutes. Events are categorized based on function area type and severity of failure. All events are systematically processed using web?based tools and stored for future analysis and evaluation of failure methods and process improvement and prioritization of efforts in an individual RT facility.

S Mutic; P Parikh; E Klein; R Drzymala; J Michalski; D Low

2008-01-01T23:59:59.000Z

40

A Multicenter Phase II Study of Local Radiation Therapy for Stage IEA Mucosa-Associated Lymphoid Tissue Lymphomas: A Preliminary Report From the Japan Radiation Oncology Group (JAROG)  

Science Journals Connector (OSTI)

Purpose The aim of this study was to evaluate the efficacy and toxicity of moderate dose radiation therapy (RT) for mucosa-associated lymphoid tissue (MALT) lymphoma in a prospective multicenter phase II trial. Methods and Materials The subjects in this study were 37 patients with MALT lymphoma between April 2002 and November 2004. There were 16 male and 21 female patients, ranging in age from 24 to 82 years, with a median of 56 years. The primary tumor originated in the orbit in 24 patients, in the thyroid and salivary gland in 4 patients each, and 5 in the others. The median tumor dose was 30.6 Gy (range, 30.6–39.6 Gy), depending on the primary site and maximal tumor diameter. The median follow-up was 37.3 months. Results Complete remission (CR) or CR/unconfirmed was achieved in 34 patients (92%). The 3-year overall survival, progression-free survival, and local control probability were 100%, 91.9%, and 97.3%, respectively. Thirteen patients experienced Grade 1 acute toxicities including dermatitis, mucositis, and conjunctivitis. One patient developed Grade 2 taste loss. Regarding late toxicities, Grade 2 reactions including hypothyroidism, and radiation pneumonitis were observed in three patients, and Grade 3 cataract was seen in three patients. Conclusions This prospective phase II study demonstrated that moderate dose RT was highly effective in achieving local control with acceptable morbidity in 37 patients with MALT lymphoma.

Koichi Isobe; Yoshikazu Kagami; Keiko Higuchi; Takeshi Kodaira; Masatoshi Hasegawa; Naoto Shikama; Masanori Nakazawa; Ichiro Fukuda; Keiji Nihei; Kana Ito; Teruki Teshima; Yoshihiro Matsuno; Masahiko Oguchi

2007-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "radiation oncology feinberg" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


41

A Paired, Double-Blind, Randomized Comparison of a Moisturizing Durable Barrier Cream to 10% Glycerine Cream in the Prophylactic Management of Postmastectomy Irradiation Skin Care: Trans Tasman Radiation Oncology Group (TROG) 04.01  

SciTech Connect

Purpose: A previous, unblinded study demonstrated that an alcohol-free barrier film containing an acrylate terpolymer (ATP) was effective in reducing skin reactions compared with a 10% glycerine cream (sorbolene). The different appearances of these products precluded a blinded comparison. To test the acrylate terpolymer principle in a double-blinded manner required the use of an alternative cream formulation, a moisturizing durable barrier cream (MDBC); the study was conducted by the Trans Tasman Radiation Oncology Group (TROG) as protocol 04.01. Methods and Materials: A total of 333 patients were randomized; 1 patient was ineligible and 14 patients withdrew or had less than 7 weeks' observations, leaving 318 for analysis. The chest wall was divided into medial and lateral compartments, and patients were randomized to have MDBC applied daily to the medial or lateral compartment and sorbolene to the other compartment. Weekly observations, photographs, and symptom scores (pain and pruritus) were collected to week 12 or resolution of skin reactions if earlier. Skin dose was confirmed by centrally calibrated thermoluminescent dosimeters. Results: Rates of medial and lateral compartment Common Toxicity Criteria (CTC), version 3, greater than or equal to grade 3 skin reactions were 23% and 41%, but rates by skin care product were identical at 32%. There was no significant difference between MDBC and sorbolene in the primary endpoint of peak skin reactions or secondary endpoints of area-under-the-curve skin reaction scores. Conclusions: The MDBC did not reduce the peak skin reaction compared to sorbolene. It is possible that this is related to the difference in the formulation of the cream compared with the film formulation. Skin dosimetry verification and double blinding are essential for radiation skin care comparative studies.

Graham, Peter H., E-mail: peter.graham@sesiahs.health.nsw.gov.au [Cancer Care Centre, St. George Hospital, Kogarah, New South Wales (Australia); Plant, Natalie; Graham, Jennifer L.; Browne, Lois [Cancer Care Centre, St. George Hospital, Kogarah, New South Wales (Australia)] [Cancer Care Centre, St. George Hospital, Kogarah, New South Wales (Australia); Borg, Martin [Department of Radiation Oncology, Royal Adelaide Hospital (Australia)] [Department of Radiation Oncology, Royal Adelaide Hospital (Australia); Capp, Anne [Department of Radiation Oncology, Mater Hospital, Newcastle, New South Wales (Australia)] [Department of Radiation Oncology, Mater Hospital, Newcastle, New South Wales (Australia); Delaney, Geoff P. [Cancer Care Centre, Liverpool Hospital, Liverpool, New South Wales (Australia)] [Cancer Care Centre, Liverpool Hospital, Liverpool, New South Wales (Australia); Harvey, Jennifer [Mater Hospital, South Brisbane, Queensland (Australia)] [Mater Hospital, South Brisbane, Queensland (Australia); Kenny, Lisbeth [Royal Brisbane Hospital, Herston, Queensland (Australia)] [Royal Brisbane Hospital, Herston, Queensland (Australia); Francis, Michael [Andrew Love Cancer Centre, Geelong (Australia)] [Andrew Love Cancer Centre, Geelong (Australia); Zissiadis, Yvonne [Department of Radiation Oncology, Royal Perth Hospital, Perth (Australia)] [Department of Radiation Oncology, Royal Perth Hospital, Perth (Australia)

2013-05-01T23:59:59.000Z

42

Motexafin-Gadolinium and Involved Field Radiation Therapy for Intrinsic Pontine Glioma of Childhood: A Children's Oncology Group Phase 2 Study  

SciTech Connect

Purpose: To evaluate the effects on 1-year event-free survival (EFS) and overall survival (OS) of combining motexafin and gadolinium (MGd), a potent radiosensitizer, with daily fractionated radiation therapy in children with newly diagnosed intrinsic pontine gliomas. Methods and Materials: Patients with newly diagnosed intrinsic pontine glioma were treated with MGd daily for 5 consecutive days each week, for a total of 30 doses. Patients received a 5- to 10-min intravenous bolus of MGd, 4.4 mg/kg/day, given 2 to 5 h prior to standard dose irradiation. Radiation therapy was administered at a daily dose of 1.8 Gy for 30 treatments over 6 weeks. The total dose was 54 Gy. Results: Sixty eligible children received MGd daily, concurrent with 6 weeks of radiation therapy. The estimated 1-year EFS was 18% {+-} 5%, and the estimated 1-year OS was 53% {+-} 6.5%. The most common grade 3 to 4 toxicities were lymphopenia, transient elevation of liver transaminases, and hypertension. Conclusions: Compared to historical controls, the addition of MGd to a standard 6-week course of radiation did not improve the survival of pediatric patients with newly diagnosed intrinsic pontine gliomas.

Bradley, Kristin A., E-mail: bradley@humonc.wisc.edu [Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin (United States); Zhou Tianni [Department of Preventive Medicine, University of Southern California, Los Angeles, California (United States)] [Department of Preventive Medicine, University of Southern California, Los Angeles, California (United States); McNall-Knapp, Rene Y. [Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma (United States)] [Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma (United States); Jakacki, Regina I. [Division of Pediatric Hematology/Oncology, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania (United States)] [Division of Pediatric Hematology/Oncology, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania (United States); Levy, Adam S. [Division of Pediatric Hematology/Oncology, Children's Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, New York (United States)] [Division of Pediatric Hematology/Oncology, Children's Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, New York (United States); Vezina, Gilbert [Department of Radiology, Children's National Medical Center, George Washington University School of Medicine, Washington, DC (United States)] [Department of Radiology, Children's National Medical Center, George Washington University School of Medicine, Washington, DC (United States); Pollack, Ian F. [Department of Neurosurgery, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania (United States)] [Department of Neurosurgery, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania (United States)

2013-01-01T23:59:59.000Z

43

A Phase II Comparative Study of Gross Tumor Volume Definition With or Without PET/CT Fusion in Dosimetric Planning for Non-Small-Cell Lung Cancer (NSCLC): Primary Analysis of Radiation Therapy Oncology Group (RTOG) 0515  

SciTech Connect

Background: Radiation Therapy Oncology Group (RTOG) 0515 is a Phase II prospective trial designed to quantify the impact of positron emission tomography (PET)/computed tomography (CT) compared with CT alone on radiation treatment plans (RTPs) and to determine the rate of elective nodal failure for PET/CT-derived volumes. Methods: Each enrolled patient underwent definitive radiation therapy for non-small-cell lung cancer ({>=}60 Gy) and had two RTP datasets generated: gross tumor volume (GTV) derived with CT alone and with PET/CT. Patients received treatment using the PET/CT-derived plan. The primary end point, the impact of PET/CT fusion on treatment plans was measured by differences of the following variables for each patient: GTV, number of involved nodes, nodal station, mean lung dose (MLD), volume of lung exceeding 20 Gy (V20), and mean esophageal dose (MED). Regional failure rate was a secondary end point. The nonparametric Wilcoxon matched-pairs signed-ranks test was used with Bonferroni adjustment for an overall significance level of 0.05. Results: RTOG 0515 accrued 52 patients, 47 of whom are evaluable. The follow-up time for all patients is 12.9 months (2.7-22.2). Tumor staging was as follows: II = 6%; IIIA = 40%; and IIIB = 54%. The GTV was statistically significantly smaller for PET/CT-derived volumes (98.7 vs. 86.2 mL; p < 0.0001). MLDs for PET/CT plans were slightly lower (19 vs. 17.8 Gy; p = 0.06). There was no significant difference in the number of involved nodes (2.1 vs. 2.4), V20 (32% vs. 30.8%), or MED (28.7 vs. 27.1 Gy). Nodal contours were altered by PET/CT for 51% of patients. One patient (2%) has developed an elective nodal failure. Conclusions: PET/CT-derived tumor volumes were smaller than those derived by CT alone. PET/CT changed nodal GTV contours in 51% of patients. The elective nodal failure rate for GTVs derived by PET/CT is quite low, supporting the RTOG standard of limiting the target volume to the primary tumor and involved nodes.

Bradley, Jeffrey, E-mail: jbradley@wustl.edu [Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO (United States); Bae, Kyounghwa [Department of Statistics, RTOG, Philadelphia, PA (United States); Choi, Noah [Massachusetts General Hospital, Boston, MA (United States); Forster, Ken [H. Lee Moffitt Cancer Center, Tampa, FL (United States); Siegel, Barry A. [Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO (United States); Brunetti, Jacqueline [Holy Name Medical Center, Teaneck, NJ (United States); Purdy, James [University of California at Davis, Davis, CA (United States); Faria, Sergio [McGill University, Montreal (Canada); Vu, Toni [Centre Hospitalier Universitaire de Montreal, Hospital Notre Dame, Montreal (Canada); Thorstad, Wade [Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO (United States); Choy, Hak [University of Texas Southwestern, Dallas, TX (United States)

2012-01-01T23:59:59.000Z

44

Carbon Beam Therapy Overcomes the Radiation Resistance of Uterine Cervical Cancer Originating from Hypoxia  

Science Journals Connector (OSTI)

...Nakano, Department of Radiation Oncology, Gunma University...Maebashi 371-8511, Japan. Phone: 81-27-220-8383...Radiological Sciences, Chiba, Japan; 2 Department of Radiation Oncology, Gunma University...Medicine, Maebashi, Japan; and 3 Department of...

Takashi Nakano; Yoshiyuki Suzuki; Tatsuya Ohno; Shingo Kato; Michiya Suzuki; Shinroku Morita; Shinichiro Sato; Kuniyuki Oka; and Hirohiko Tsujii

2006-04-01T23:59:59.000Z

45

Can We Predict Plan Quality for External Beam Partial Breast Irradiation: Results of a Multicenter Feasibility Study (Trans Tasman Radiation Oncology Group Study 06.02)  

SciTech Connect

Purpose: Partial breast irradiation (PBI) after lumpectomy may be an option for selected patients with early breast cancer. A feasibility study of accelerated PBI delivered using external beam 3-dimensional conformal radiation therapy (RT) was undertaken at 8 Australasian centers. The present study evaluated the impact of patient, tumor, and RT technique-related factors on the quality of RT plans as determined by the dose–volume parameters of organs at risk. Methods and Materials: Forty-eight patients were enrolled in the study. All RT plans were centrally reviewed using predefined dosimetric criteria before commencement and after completion of protocol therapy. The RT plans of 47 patients met the dose–volume constraints, and all 47 patients received PBI to a prescribed dose of 38.5 Gy in 10 fractions. The RT plan quality was determined by volumes of the ipsilateral whole breast, lung, and heart that received 50% and 95%; 30%; and 5% of the prescribed dose, respectively. Patient, tumor, and RT technique-related factors were investigated for association with the parameters of RT plan quality. Results: The ratio of the planning target volume to the ipsilateral whole-breast volume was significantly associated with the ipsilateral breast doses on multiple variable analyses. The distance of the postlumpectomy surgical cavity from the heart and lung were predictive for heart and lung doses, respectively. A distance between surgical cavity and heart of >4 cm typically resulted in <1% of the heart volume receiving 5 Gy or less. It was more difficult to meet the heart dose constraint for left-sided and medially located tumors. Conclusions: Partial breast irradiation using 3-dimensional conformal RT was feasible within the study constraints. The ratio of planning target volume to ipsilateral whole-breast volume and the distance of surgical cavity from the heart were significant predictors of the quality of treatment plan for external beam PBI.

Kron, Tomas, E-mail: Tomas.Kron@petermac.org [Peter MacCallum Cancer Centre, Departments of Radiation Oncology, Physical Sciences and Radiation Therapy, Melbourne, Victoria (Australia); Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria (Australia); School of Science, Engineering and Technology, Royal Melbourne Institute of Technology University, Melbourne, Victoria (Australia); Willis, David; Link, Emma [Peter MacCallum Cancer Centre, Departments of Radiation Oncology, Physical Sciences and Radiation Therapy, Melbourne, Victoria (Australia); Lehman, Margot [Princess Alexandra Hospital, Department of Radiation Oncology, Brisbane, Queensland (Australia); Campbell, Gillian [Auckland City Hospital, Department of Radiation Oncology, Auckland (New Zealand); O'Brien, Peter [Newcastle Calvary Mater Hospital, Department of Radiation Oncology, Newcastle, NSW (Australia); Chua, Boon [Peter MacCallum Cancer Centre, Departments of Radiation Oncology, Physical Sciences and Radiation Therapy, Melbourne, Victoria (Australia); Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria (Australia)

2013-11-15T23:59:59.000Z

46

Lessons Learned from Radiation Oncology Clinical Trials  

Science Journals Connector (OSTI)

...usually located the Go-Gi at a point midway between the diploid and aneuploid peaks...locating the Go-Gi peak at a point midway between the diploid {(.,,(,, z...peak position would usually be assigned midway between the aneuploid and diploid peaks...

Fei-Fei Liu; for the workshop participants; Paul Okunieff; Eric J. Bernhard; Helen B. Stone; Stephen Yoo; C. Norman Coleman; Bhadrasain Vikram; Martin Brown; John Buatti; Chandan Guha

2013-11-15T23:59:59.000Z

47

Lessons Learned from Radiation Oncology Clinical Trials  

Science Journals Connector (OSTI)

...used to change an aspect of the trial midway. In the Biomarkers-Integrated Approaches...Therapy for Lung Cancer Elimination (BATTLE) trial, 40% of the patients were randomly...Blumenschein GR, Jr, Tsao A, et alThe BATTLE trial: personalizing therapy for lung...

Fei-Fei Liu; for the workshop participants; Paul Okunieff; Eric J. Bernhard; Helen B. Stone; Stephen Yoo; C. Norman Coleman; Bhadrasain Vikram; Martin Brown; John Buatti; and Chandan Guha

2013-11-15T23:59:59.000Z

48

The Ethics of Phase 0 Oncology Trials  

Science Journals Connector (OSTI)

...Cancer Research CCR Focus CCR Focus The Ethics of Phase 0 Oncology Trials Emily Abdoler...feasibility, community acceptance, and ethics (8-13). This last topic is the subject...these trials (1, 2, 4, 6, 14). Ethics of Phase I Oncology Trials Given the small...

Emily Abdoler; Holly Taylor; David Wendler

2008-06-15T23:59:59.000Z

49

How radiation exposure affects immunogenetical risk of stomach cancer among atomic-bomb survivors  

Science Journals Connector (OSTI)

...Targeted alpha-Particle Radiation Therapy Kwamena E. Baidoo...comparison of the structure of radiation oncology in the United States and Japan.Int J Radiat Oncol Biol...FAQs/Fast-Facts-About-Radiation-Therapy/Index.aspx...

Tomonori Hayashi; Kazue Imai; Yoichiro Kusunoki; Kei Nakachi; and Eiichi Tahara

2005-05-01T23:59:59.000Z

50

PP2A regulates ionizing radiation–induced apoptosis through Ser46 phosphorylation of p53  

Science Journals Connector (OSTI)

...Articles PP2A regulates ionizing radiation-induced apoptosis through Ser46...virginia.edu 1 Department of Radiation Oncology and 2 Center for Cell...and Dental University, Tokyo, Japan). Radiation Treatment Cell cultures were irradiated...

Jun Mi; Elzbieta Bolesta; David L. Brautigan; and James M. Larner

2009-01-01T23:59:59.000Z

51

Phase I/II trial of initial treatment with chemo-radiation in patients with highly advanced gastric adenocarcinoma  

Science Journals Connector (OSTI)

...CA Phase II study of radiation therapy combined with...Kitasato Gynecologic Radiation Oncology Group (KGROG...Medicine, Sagamihara, Japan, Kitasato University...chemoradiotherapy with lesser radiation dose for LAUCC using...Pharmaceutical Co., Japan. If this phase II trial...

Kohshi Kumagai; Yoshiro Saikawa; Ryo Ito; Takahiro Igarashi; Tsuyoshi Kiyota; Rieko Nakamura; Masaki Ohashi; Norihito Wada; Masashi Yoshida; Tetsuro Kubota; Koichiro Kumai; and Masaki Kitajima

2007-05-01T23:59:59.000Z

52

Polymorphisms in DNA Repair Genes, Medical Exposure to Ionizing Radiation, and Breast Cancer Risk  

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...Session Abstracts Treatment Radiation Therapy CTRC-AACR San...breast-conserving therapy in Japan: comparison of the treatment...Mitsumori 1 1 Department of Radiation Oncology and Image-Applied...Kyoto University, Kyoto, Japan 2 Department of Radiology...

Robert C. Millikan; Jon S. Player; Allan Rene deCotret; Chiu-Kit Tse; and Temitope Keku

2005-10-01T23:59:59.000Z

53

Collection and Use of Family History in Oncology Clinics  

E-Print Network (OSTI)

Collection and Use of Family History in Oncology Clinics TO THE EDITOR: The American Society of Clinical Oncology expert statement1 covered many helpful aspects of the clinical use of a family history-Cancer Database,relatingtotheproportionoffamilialcancers.3 Totalcancers in the offspring population (maximal age

Hemminki, Akseli

54

Pre-Clinical Radiation Biology and Medical Physics Divisions  

E-Print Network (OSTI)

the uncertainties". Consider the uncertainties in delivering and measuring a dose of radiation to a certain tissue; There are uncertainties inherent in the dose measurement and calculation process Estimates of these uncertainties (forPre-Clinical Radiation Biology and Medical Physics Divisions Department of Radiation Oncology Tom

55

The New Radiation Therapy Clinical Practice: The Emerging Role of Clinical Peer Review for Radiation Therapists and Medical Dosimetrists  

SciTech Connect

The concept of peer review for radiation therapists and medical dosimetrists has been studied very little in radiation oncology practice. The purpose of this manuscript is to analyze the concept of peer review in the clinical setting for both radiation therapists and medical dosimetrists. The literature reviewed both the percentages and causes of radiation therapy deviations. The results indicate that peer review can be both implemented and evaluated into both the radiation therapist and medical dosimetrist clinical practice patterns.

Adams, Robert D.; Marks, Lawrence B. [UNC Department of Radiation Oncology, Chapel Hill, NC (United States); Pawlicki, Todd [Department of Radiation Oncology, University of California, San Diego, CA (United States); Hayman, James [Department of Radiation Oncology, University of Michigan, Ann Arbor, MI (United States); Church, Jessica, E-mail: jachurch@email.unc.ed [Department of Radiation Oncology, University of Michigan, Ann Arbor, MI (United States)

2010-01-01T23:59:59.000Z

56

Assessing the impact of tumor evolution on oncology drug development and commercialization  

E-Print Network (OSTI)

This thesis investigates the commercial viability of developing and commercializing targeted oncology drugs directed at a specific tumor mutation instead of all forms and mutations of a single target. While oncologic drugs ...

Sterk, Joseph P. (Sterk, Joseph Phillip)

2011-01-01T23:59:59.000Z

57

In Memoriam: Donald L. Morton, MD (1934–2014): An Icon in Surgical Oncology  

Science Journals Connector (OSTI)

Donald Morton was truly a legend in surgical oncology, an icon as a surgical investigator, a pioneer in...

Charles M. Balch MD; FACS; Mark S. Roh MD…

2014-05-01T23:59:59.000Z

58

Patterns of Care Study of radiation therapy for uterine cervix cancer in Japan: The influence of age on the process  

Science Journals Connector (OSTI)

Background. To improve the quality of radiation oncology in Japan, a Patterns of Care Study (PCS) ... in the United States, was introduced to Japan. In this study, the process, including...

T. Teshima; Hiroshi Ikeda; Mitsuyuki Abe…

1999-02-01T23:59:59.000Z

59

Control Group Variation in the Janus Studies  

NLE Websites -- All DOE Office Websites (Extended Search)

Group Variation in the Janus Studies Group Variation in the Janus Studies Benjamin Haley 1 , William Liu 1 , Mary J. Kwasny 2 , Tatjana Paunesku 1 , Gayle Woloschak 1 1. Department of Radiation Oncology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611 2. Department of Preventative Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611 Data from historical radiobiological mega-studies is being migrated online to enable open access to the results of these studies. The availability of these large data sets offers the possibility of merging the results of multiple studies for meta-analysis. However, researchers must overcome several hurdles in order to analyze data from disparate radiobiology studies. Variations in animal treatment, autopsy methods, and nomenclature must be accounted for before developing

60

Low Dose Radiation Research Program: Universities  

NLE Websites -- All DOE Office Websites (Extended Search)

Universities Universities | Duke University | Loma Linda University | Northwestern University | University of Chicago | University of California Davis | Northwestern University University of Chicago University of California Davis Effects of Low Dose Irradiation on NF-κB Signaling Networks and Mitochondria Principal Investigator: Dr. Gayle Woloschak DOE Low Dose Research Program Projects Low dose-low dose rate irradiation leads to long term changes in numbers of mitochondria and mitochondrial genomes - Principal Investigator: Gayle Woloschak, Professor, Department of Radiation Oncology, Northwestern University, Chicago, IL, USA NF-κB-mediated pro-survival network in low dose radiation-induced adaptive protection - Principal Investigator: Jian Jian Li, Professor, Department of Radiation Oncology, University of California Davis, Davis,

Note: This page contains sample records for the topic "radiation oncology feinberg" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


61

E-Print Network 3.0 - asian oncology summit Sample Search Results  

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with the other... Asian Countries, provides India with a forum for interaction with ASEAN members. Besides these inter... , Oncology, Oil Seeds and Soil Microbiology, and...

62

Low Dose Radiation Research Program: DOE Lowdose Radiation Program Workshop  

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Using a Low LET Electron Microbeam to Investigate Non-Targeted Using a Low LET Electron Microbeam to Investigate Non-Targeted Effects of Low Dose Radiation. Authors: William F. Morgan1 and Marianne B. Sowa2 Institutions: 1Radiation Oncology Research Laboratory, University of Maryland, Baltimore MD 21201 2 Chemical Structure and Dynamics, Pacific Northwest National Laboratory, Richland WA 99352 We have recently installed a low LET electron microbeam that generates energetic electrons to mimic radiation damage from gamma and x-ray sources. It has been designed such that high-energy electrons deposit energy in a pre-selected subset of cells leaving neighboring cells unirradiated (Figure 1). In this way it is possible to examine non-targeted effects associated with low dose radiation exposure including induced genomic instability and

63

Surgeons' Knowledge and Practices Regarding the Role of Radiation Therapy in Breast Cancer Management  

SciTech Connect

Purpose: Population-based studies suggest underuse of radiation therapy, especially after mastectomy. Because radiation oncology is a referral-based specialty, knowledge and attitudes of upstream providers, specifically surgeons, may influence patients' decisions regarding radiation, including whether it is even considered. Therefore, we sought to evaluate surgeons' knowledge of pertinent risk information, their patterns of referral, and the correlates of surgeon knowledge and referral in specific breast cancer scenarios. Methods and Materials: We surveyed a national sample of 750 surgeons, with a 67% response rate. We analyzed responses from those who had seen at least 1 breast cancer patient in the past year (n=403), using logistic regression models to identify correlates of knowledge and appropriate referral. Results: Overall, 87% of respondents were general surgeons, and 64% saw >10 breast cancer patients in the previous year. In a scenario involving a 45-year-old undergoing lumpectomy, only 45% correctly estimated the risk of locoregional recurrence without radiation therapy, but 97% would refer to radiation oncology. In a patient with 2 of 20 nodes involved after mastectomy, 30% would neither refer to radiation oncology nor provide accurate information to make radiation decisions. In a patient with 4 of 20 nodes involved after mastectomy, 9% would not refer to radiation oncology. Fewer than half knew that the Oxford meta-analysis revealed a survival benefit from radiation therapy after lumpectomy (45%) or mastectomy (32%). Only 16% passed a 7-item knowledge test; female and more-experienced surgeons were more likely to pass. Factors significantly associated with appropriate referral to radiation oncology included breast cancer volume, tumor board participation, and knowledge. Conclusions: Many surgeons have inadequate knowledge regarding the role of radiation in breast cancer management, especially after mastectomy. Targeted educational interventions may improve the quality of care.

Zhou, Jessica [Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan (United States); Griffith, Kent A. [Department of Biostatistics, University of Michigan, Ann Arbor, Michigan (United States); Hawley, Sarah T.; Zikmund-Fisher, Brian J. [Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan (United States); Janz, Nancy K. [Department of Health Behavior and Health Education, University of Michigan School of Public Health, Ann Arbor, Michigan (United States); Sabel, Michael S. [Department of Surgery, University of Michigan, Ann Arbor, Michigan (United States); Katz, Steven J. [Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan (United States); Jagsi, Reshma, E-mail: rjagsi@med.umich.edu [Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan (United States)

2013-12-01T23:59:59.000Z

64

Bridging the "Valley of Death" in stratified medicine : commercializing molecular diagnostics in oncology  

E-Print Network (OSTI)

Historically, the development of molecular companion diagnostics in oncology has underwhelmed the expectation of the medical field since the successful mapping of the human genome a decade ago. There have been several ...

Copp, Joshua

2012-01-01T23:59:59.000Z

65

Econogenomics 2007: When Does the Inclusion of Biomarkers in Oncology Drug Development Make Economic Sense?  

Science Journals Connector (OSTI)

...Atlanta, GA Econogenomics 2007: When Does the Inclusion of Biomarkers in Oncology...fill up with approved agents. [ ] Two fundamental problems appear to dominate modern cancer...molecular basis of the stratification does not generalize to other cancer types...

Thomas Roberts

2007-10-01T23:59:59.000Z

66

Low Dose Radiation Research Program: Radiation-Induced Nuclear Factor kB  

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Radiation-Induced Nuclear Factor kB mediates survival advantage by Radiation-Induced Nuclear Factor kB mediates survival advantage by Telomerase Activation. Authors: Natarajan M.,1 Mohan S.,2 Pandeswara, S.L.,1 and Herman T.S.1 Institutions: Departments of 1Radiation Oncology and 2Pathology, The University of Texas Health Science Center, San Antonio, Texas Activation of NF-kB in response to low doses of ionizing radiation was first shown in our laboratory. Although studies have shown that NF-kB plays an important role in anti-apoptotic function, little has been done to understand the molecular link between the activation of NF-kB and cellular outcome such as enhanced cell survival after low dose low-linear transfer (LET) radiation. Because upregulation of telomerase activity is associated with longevity and allows cells to escape from senescence, we hypothesize

67

Association between Ambient Ultraviolet Radiation and Risk of Epithelial Ovarian Cancer  

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...Boscoe FP , Schymura MJ.Solar ultraviolet-B exposure and...Spain with respect to indices of solar UVB irradiance and smoking...a case-control study in Mexico.Oncology 2002;63:151-7...suggest that higher exposure to solar ultraviolet radiation (UVR...

Bich Tran; Susan J. Jordan; Robyn Lucas; Penelope M. Webb; and Rachel Neale

2012-11-01T23:59:59.000Z

68

Low Dose Radiation Research Program: Research Program Workshop I Abstracts  

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Genetic Factors Affecting Susceptibility to Low-Dose Radiation Genetic Factors Affecting Susceptibility to Low-Dose Radiation William F. Morgan and John H.J. Petrini Radiation Oncology Research Laboratory, University of Maryland at Baltimore, Baltimore, MD Summary: The goal of our application is to improve the scientific basis for understanding potential risks to the population from low dose radiation exposure based on potential genetic differences that may modulate an individual's sensitivity to low doses of radiation. Abstract: The goal of this application is to improve the scientific basis for understanding potential risks to the population from low dose radiation exposure. We propose to address specific genetic factors that affect individual susceptibility to low dose radiation and ask the question do genetic differences exist that make some individuals more sensitive to

69

Report from the Radiation Therapy Committee of the Southwest Oncology Group (SWOG): Research Objectives Workshop 2008  

Science Journals Connector (OSTI)

...1222-6. 37 Martin LP , Hamilton TC Schilder RJ. Platinum resistance: the...178-81. 68 Fuster JJ , Sanz-Gonzalez SM, Moll UM Andres V. Classic and novel...nonane thiosemicarbazone complexes: radiopharmaceuticals for PET of topoisomerase II expression...

Paul Okunieff; Lisa A. Kachnic; Louis S. Constine; Clifton D. Fuller; Laurie E. Gaspar; Daniel F. Hayes; Jean Hooks; Clifton Ling; Frank L. Meyskens, Jr.; Philip A. Philip; David Raben; Stephen R. Smalley; Gregory P. Swanson; Beverly A. Teicher; Charles R. Thomas, Jr.; Bhadrasain Vikram; Michael J. Zelefsky; and Laurence H. Baker

2009-09-15T23:59:59.000Z

70

Making the right software choice for clinically used equipment in radiation oncology  

Science Journals Connector (OSTI)

The analysis of the features in the above mentioned groups are summarised in Table  1, Table  2, Table  3, Table  4, and Table  5.... For clarity the data were divided into three classifications safety, accuracy ...

Hilke Vorwerk; Klemens Zink; Daniela Michaela Wagner…

2014-06-01T23:59:59.000Z

71

PROGRAMME SPECIFICATION UNDERGRADUATE PROGRAMMES Programme name Radiography (Radiotherapy and Oncology)  

E-Print Network (OSTI)

the department within the legislative framework relating to radiation protection Skills: Undertake treatment set their knowledge of healthcare technology and their excellent interpersonal skills, to plan and deliver accurate

Weyde, Tillman

72

Omics-based nanomedicine: The future of personalized oncology  

Science Journals Connector (OSTI)

Abstract The traditional “one treatment fits all” paradigm disregards the heterogeneity between cancer patients, and within a particular tumor, thus limit the success of common treatments. Moreover, current treatment lacks specificity and therefore most of the anticancer drugs induce severe adverse effects. Personalized medicine aims to individualize therapeutic interventions, based on the growing knowledge of the human multiple ‘-oms’ (e.g. genome, epigenome, transcriptome, proteome and metabolome), which has led to the discovery of various biomarkers that can be used to detect early stage cancers and predict tumor progression, drug response, and clinical outcome. Nanomedicine, the application of nanotechnology to healthcare, holds great promise for revolutionizing disease management such as drug delivery, molecular imaging, reduced adverse effects and the ability to contain both therapeutic and diagnostic modalities simultaneously termed theranostics. Personalizednanomedicine has the power of combining nanomedicine with clinical and molecular biomarkers (“OMICS” data) achieving improve prognosis and disease management as well as individualized drug selection and dosage profiling to ensure maximal efficacy and safety. Tumor’s heterogeneity sets a countless challenge for future personalized therapy in cancer, however the use of multi-parameter ‘omic’s data for specific molecular biomarkers recognition together with versatile drug delivery nanocarriers, which could target concomitantly and specifically tumor cells subpopulations, might heralds a brighter future for personalized cancer management. In this review, we present the current leading technologies available for personalized oncology. We discusses the immense potential of combining the best of these two worlds, nanomedicine and high throughput OMICS technologies to pave the way towards cancer personalized medicine.

Daniel Rosenblum; Dan Peer

2014-01-01T23:59:59.000Z

73

Low Dose Radiation Research Program: 2003 Molecular Characterization of the  

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Characterization of the Roles of SOD Genes in Mammalian Characterization of the Roles of SOD Genes in Mammalian Cellular Response to Low Dose Radiation Authors: Chuan-Yuan Li,1 Eric Chuang2 Institutions: 1Dept of Radiation Oncology, Duke University Medical Center, Durham, NC, 2Advanced Technology Center, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland The potential risks of exposure to low dose radiation are of major concerns to the DOE/OBER Low Dose Radiation Research Program. It has been long recognized that much of the radiation-induced genetic damage to cells are caused by secondary oxidative species. Therefore, internal cellular defense systems against oxidative stress play significant roles in countering genetic damage induced by ionizing radiation. The role of the detoxifying

74

Low Dose Radiation Research Program: Molecular Characterization of the  

NLE Websites -- All DOE Office Websites (Extended Search)

Molecular Characterization of the Roles of SOD Genes in Mammalian Molecular Characterization of the Roles of SOD Genes in Mammalian Cellular Response to Low Dose Radiation Authors: Chuan-Yuan Li, Zhanjun Guo, Zhonghui Yang, and Eric Chuang Institutions: Dept of Radiation Oncology, Duke University Medical Center, Durham, NC Advanced Technology Center, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland Background The potential risks of exposure to low dose radiation are of major concerns to the DOE/OBER Low Dose Radiation Research Program. It has been long recognized that much of the radiation-induced genetic damage to cells are caused by secondary oxidative species. Therefore internal cellular defense systems against oxidative stress play significant roles in countering genetic damage induced by ionizing radiation. The role of the detoxifying

75

Hydrogen peroxide significantly contributes to radiation-induced genomic instability  

NLE Websites -- All DOE Office Websites (Extended Search)

peroxide significantly contributes to radiation- peroxide significantly contributes to radiation- induced genomic instability Disha Dayal 1 , Sean M. Martin 1 , Sujatha Venkataraman 1 , Charles L. Limoli 2 , Douglas R Spitz 1 . 1 Free Radical and Radiation Biology Program, The University of Iowa, Iowa City, IA- 52246, 2 Department of Radiation Oncology, The University of California, Irvine, CA-92697 Chronic metabolic oxidative stress is associated with genomic instability following exposure to ionizing radiation (IR). Mitochondria have long been known to be a major source of reactive oxygen species (ROS) capable of causing oxidative stress. We hypothesized that radiation damages mitochondria, leading to oxidative stress and eventually genomic instability. This hypothesis is based on preliminary studies in parental

76

Radiation exposure received by the medical radiation workers in Lithuania at The Institute of Oncology, Vilnius University, 2004–2011  

Science Journals Connector (OSTI)

......non-parametric tests were used. The Mann-Whitney and Kruskal-Wallis tests were used to compare the effective doses among...Mann-Whitney test was used to compare two groups and the Kruskal-Wallis test to compare three or more groups. The value......

Vitalija Samerdokiene; Vydmantas Atkocius; Renata Ofomala

2013-11-01T23:59:59.000Z

77

Statistical Issues and Recommendations for Noninferiority Trials in Oncology: A Systematic Review  

Science Journals Connector (OSTI)

...had a prespecified plan of switching using...noninferiority design This review suggested that the...diluted. Therefore, regulatory authorities suggest...oncology: a systematic review. | To provide an...conducted a systematic review of randomized trials...6%) presented plans for switching from...

Shiro Tanaka; Yousuke Kinjo; Yoshiki Kataoka; Kenichi Yoshimura; and Satoshi Teramukai

2012-04-01T23:59:59.000Z

78

Alpha Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Basics of Radiation Basics of Radiation Gamma Radiation and X-Rays Beta Radiation Alpha Radiation Irradiation Radioactive Contamination Definitions Detection Measurement Safety Around Radiation Sources Types of Radiation Exposure Managing Radiation Emergencies Basics of Radiation Characteristics of Alpha Radiation 1. Alpha radiation is not able to penetrate skin. 2. Alpha-emitting materials can be harmful to humans if the materials are inhaled, swallowed, or absorbed through open wounds. 3. A variety of instruments have been designed to measure alpha radiation. Special training in use of these instruments is essential for making accurate measurements. 4. A civil defense instrument (CD V-700) cannot detect the presence of radioactive materials that produce alpha radiation unless the radioactive materials also produce beta and/or gamma radiation.

79

Radiation: Radiation Control (Indiana)  

Energy.gov (U.S. Department of Energy (DOE))

It is the policy of the state to encourage the constructive uses of radiation and to control its harmful effects. This section contains regulations pertaining to the manufacture, use,...

80

Origins and consequences of radiationÂ…induced centrosome aberrations  

NLE Websites -- All DOE Office Websites (Extended Search)

Origins and consequences of radiation-induced centrosome aberrations Origins and consequences of radiation-induced centrosome aberrations Sangeetha Vijayakumar, Nisarg Shah, Ignacio Fernandez-Garcia, Mary Helen Barcellos-Hoff Department of Radiation Oncology, New York University School of Medicine, NY, NY. Centrosome aberrations are frequently observed in pre-neoplastic breast lesions and are known to drive chromosomal instability (Lingle et al., 2002). Previous studies from our lab have shown that human mammary epithelial cells exposed to low doses of radiation exhibit centrosome aberrations (CAs) in a dose dependent manner from 10-200 cGy (Maxwell et al., 2008). These data demonstrated that radiation-induced CAs actually precede and generate genomic instability and that TGFβ is a key mediator

Note: This page contains sample records for the topic "radiation oncology feinberg" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


81

Oral-dental concerns of the pediatric oncology patient  

SciTech Connect

One of the main concerns of all disciplines in health care today is maintaining the patient's quality of life and comfort during cancer therapy. Oral complications resulting from radiation or chemotherapy can be expected in a large percentage of patients. Conducting a dental evaluation and performing treatment before therapy can help prevent or lessen potential complications. With preventive care and fewer infections, the patient will be able to communicate with friends and family, and optimum care and comfort can be provided.

Lawson, K.

1989-01-01T23:59:59.000Z

82

Low Dose Radiation Research Program: Adaptive Response of Mouse Skin  

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Adaptive Response of Mouse Skin Epithelial Cells to Low Dose Adaptive Response of Mouse Skin Epithelial Cells to Low Dose Ionizing Radiation: Induction of NF-κB, MnSOD, 14-3-3ζ and Cyclin B1 Authors: Jian Jian Li, Kazi M. Ahmed, Ming Fan, Shaozhong Dong, Douglas R. Spitz, and Cheng-Rong Yu Institutions: Division of Molecular Radiobiology, Purdue University School of Health Sciences, West Lafayette, Indiana; Free Radical and Radiation Biology Program, Department of Radiation Oncology, Holden Comprehensive Cancer Center, The University of Iowa, Iowa City, Iowa; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland Gene expression profiles demonstrate that a group of key stress-responsive genes are associated with radiation exposure and may contribute to cellular

83

Measured dose rate constant from oncology patients administered 18F for positron emission tomography  

SciTech Connect

Purpose: Patient exposure rate measurements verify published patient dose rate data and characterize dose rates near 2-18-fluorodeoxyglucose ({sup 18}F-FDG) patients. A specific dose rate constant based on patient exposure rate measurements is a convenient quantity that can be applied to the desired distance, injection activity, and time postinjection to obtain an accurate calculation of cumulative external radiation dose. This study reports exposure rates measured at various locations near positron emission tomography (PET) {sup 18}F-FDG patients prior to PET scanning. These measurements are normalized for the amount of administered activity, measurement distance, and time postinjection and are compared with other published data. Methods: Exposure rates were measured using a calibrated ionization chamber at various body locations from 152 adult oncology patients postvoid after a mean uptake time of 76 min following injection with a mean activity of 490 MBq {sup 18}F-FDG. Data were obtained at nine measurement locations for each patient: three near the head, four near the chest, and two near the feet. Results: On contact with, 30 cm superior to and 30 cm lateral to the head, the mean (75th percentile) dose rates per unit injected activity at 60 min postinjection were 0.482 (0.511), 0.135 (0.155), and 0.193 (0.223) {mu}Sv/MBq h, respectively. On contact with, 30 cm anterior to, 30 cm lateral to and 1 m anterior to the chest, the mean (75th percentile) dose rates per unit injected activity at 60 min postinjection were 0.623 (0.709), 0.254 (0.283), 0.190 (0.218), and 0.067 (0.081) {mu}Sv/MBq h respectively. 30 cm inferior and 30 cm lateral to the feet, the mean (75th percentile) dose rates per unit injected activity at 60 min postinjection were 0.024 (0.022) and 0.039 (0.044) {mu}Sv/MBq h, respectively. Conclusions: The measurements for this study support the use of 0.092 {mu}Sv m{sup 2}/MBq h as a reasonable representation of the dose rate anterior from the chest of patients immediately following injection. This value can then be reliably scaled to the desired time and distance for planning and staff dose evaluation purposes. At distances closer than 1 m, a distance-specific dose rate constant of 0.367 {mu}Sv/MBq h at 30 cm is recommended for accurate calculations. An accurate patient-specific dose rate constant that accounts for patient-specific variables (e.g., distribution and attenuation) will allow an accurate evaluation of the dose rate from a patient injected with an isotope rather than simply utilizing a physical constant.

Quinn, Brian; Holahan, Brian; Aime, Jean; Humm, John; St Germain, Jean; Dauer, Lawrence T. [Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10065 (United States); Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10065 (United States); Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10065 (United States) and Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10065 (United States); Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10065 (United States); Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10065 (United States) and Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10065 (United States)

2012-10-15T23:59:59.000Z

84

About Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation Radiation What is radiation? Radiation is a form of energy that is a part of our everyday lives. All of us receive a "dose" of radiation each day. Most of the dose comes from naturally occurring radioactive materials such as uranium, thorium, radon, and certain forms of potassium and carbon. The air we breathe contains radon, the food we eat contains uranium and thorium from the soil, and our bodies contain radioactive forms of potassium and carbon. Cosmic radiation from the sun also contributes to our natural radiation dose. We also receive radiation doses from man-made sources such as X-rays, nuclear medical procedures, power plants, smoke detectors and older television sets. Some people, such as nuclear plant operators, flight crews, and nuclear medicine staff may also receive an occupational radiation dose.

85

Danger radiations  

ScienceCinema (OSTI)

Le conférencier Mons.Hofert parle des dangers et risques des radiations, le contrôle des zones et les précautions à prendre ( p.ex. film badge), comment mesurer les radiations etc.

None

2011-04-25T23:59:59.000Z

86

Low Dose Radiation Research Program: Modeling Intercellular Interactions  

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Modeling Intercellular Interactions During Radiation Carcinogenesis Modeling Intercellular Interactions During Radiation Carcinogenesis Authors: Rainer K Sachs,1 Michael Chan,2 Lynn Hlatky,3 Philip Hahnfeldt3 Institutions: 1Departments of Mathematics and Physics, University of California Berkeley California; 2School of Medicine, University of California at San Diego, La Jolla California; 3Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston Massachusetts Abstract By modulating the microenvironment of malignant or pre-malignant epithelial cells, inhibitory or stimulatory signals from nearby cells, including those in stromal and vascular tissues, can play a key role in carcinogenesis; cancer is ultimately a disease of a whole-cell community, not just of a single cell, clone, or cell lineage. However, current commonly used

87

Modulating radiation induced TGFβ and ATM signaling in the DNA damage  

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Modulating radiation induced TGFβ and ATM signaling in the DNA damage Modulating radiation induced TGFβ and ATM signaling in the DNA damage response Jennifer A. Anderson Gray Institute for Radiation Oncology and Biology Abstract Both the ATM and TGFβ signal transduction pathways are essential for cellular and tissue control responses to ionizing radiation and aberrant modifications to these pathways are extensive in cancer. We hypothesize that the ATM and TGFβ signaling pathways are fully induced at high doses of acute low-LET radiation, whereas only partially induced at low doses. Numerous studies have linked the p38 MAPK signaling pathway with the ATM DNA damage response, and others have shown that TGFβ stimulation results in the phosphorylation of p38 MAPK. Our aim is to perturb potential crosstalk between ATM, TGFβ and p38 MAPK at the DNA damage level and

88

Low-Dose Ionizing Radiation Alters the Epigenome of the Avy Mouse  

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Ionizing Radiation Alters the Epigenome of the A Ionizing Radiation Alters the Epigenome of the A vy Mouse Autumn Bernal 1,2,3 , Dale Huang 1 , Yue Li 4 , Dana Dolinoy 5 , and Randy Jirtle 1 Department of Radiation Oncology 1 , University Program in Genetics and Genomic 2 , Integrated Toxicology & Environmental Health Program 3 , Department of Community and Family Medicine 4 , Duke University Medical Center, Durham, NC, USA, Department of Environmental and Health Sciences, University of Michigan, Ann Arbor, MI, USA 4 Background: Humans have evolved and thrived amidst constant low-dose (0-10 cGy) background radiation exposure from natural sources. Currently, however, the frequency of exposures to low doses of radiation is increasing due to man-made sources such as diagnostic imaging and nuclear power. This increased exposure has led to concerns amongst the general public and the government about the

89

Low Dose Radiation Research Program: Using a Low LET Electron Microbeam to  

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a Low LET Electron Microbeam to Investigate Non-Targeted Effects of a Low LET Electron Microbeam to Investigate Non-Targeted Effects of Low Dose Radiation William F. Morgan Radiation Oncology Research Laboratory, Pacific Northwest National Laboratory Why this Project? To examine genomic instability and bystander effects as non-targeted effects associated with low dose radiation exposure. Project Goals To provides a robust, reliable, highly sensitive assay for detecting delayed events occurring in cells exposed to low doses of ionizing radiation. Experimental Approach To mimic radiation damage from gamma and x-ray sources, a low-LET electron microbeam that generates energetic electrons has been designed such that high-energy electrons deposit energy in a pre-selected subset of cells leaving neighboring cells unirradiated. Using a novel green fluorescence gene (GFP) reporter assay, a high through

90

How Do the ASTRO Consensus Statement Guidelines for the Application of Accelerated Partial Breast Irradiation Fit Intraoperative Radiotherapy? A Retrospective Analysis of Patients Treated at the European Institute of Oncology  

SciTech Connect

Purpose: To verify how the classification according to the American Society for Therapeutic Radiation Oncology (ASTRO) consensus statement (CS) for the application of accelerated partial breast irradiation (APBI) fits patients treated with intraoperative radiotherapy with electrons (ELIOT) at a single institution. Methods and Materials: The study included 1,822 patients treated with ELIOT as the sole radiation modality outside of a clinical trial at the European Institute of Oncology after breast-conserving surgery for invasive breast cancer, who were classified into CS groups of suitable, cautionary, and unsuitable. The outcome in terms of ipsilateral breast recurrence, regional node relapse, distant metastases, progression free-survival, cause-specific survival, and overall survival were assessed. Results: All the 1,822 cases except for 25 could be classified according to ASTRO CS: 294 patients met the criteria for inclusion into the suitable group, 691 patients into the cautionary group, and 812 patients into the unsuitable group. The 5-year rate of ipsilateral breast recurrence for suitable, cautionary, and unsuitable groups were 1.5%, 4.4%, and 8.8%, respectively (p = 0.0003). Whereas the regional node relapse showed no difference, the rate of distant metastases was significantly different in the unsuitable group compared with the suitable and cautionary groups, having a significant impact on survival. Conclusion: In the context of patients treated with ELIOT, the ASTRO guidelines identify well the groups for whom APBI might be considered as an effective alternative to whole breast radiotherapy and also identify groups for whom APBI is not indicated.

Leonardi, Maria Cristina, E-mail: cristina.leonardi@ieo.it [Division of Radiation Oncology, European Institute of Oncology, Milan (Italy); Maisonneuve, Patrick [Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan (Italy); Mastropasqua, Mauro Giuseppe [Division of Pathology, European Institute of Oncology, Milan (Italy); Morra, Anna; Lazzari, Roberta [Division of Radiation Oncology, European Institute of Oncology, Milan (Italy); Rotmensz, Nicole [Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan (Italy); Sangalli, Claudia; Luini, Alberto [Division of Breast Surgery, European Institute of Oncology, Milan (Italy); Veronesi, Umberto [Scientific Directorate, European Institute of Oncology, Milan (Italy); Orecchia, Roberto [Division of Radiation Oncology, European Institute of Oncology, Milan (Italy); University of Milan (Italy)

2012-07-01T23:59:59.000Z

91

Plasma Radiation  

Science Journals Connector (OSTI)

... JUST over ten years ago the first book on plasma physics as a subject in its own right appeared; in a gradually swelling stream ... been surprisingly few monographs. One topic which has had scant coverage in any form is plasma radiation (except for spectral-line radiation which has been dealt with very fully in ...

T. J. M. BOYD

1967-07-01T23:59:59.000Z

92

High LET radiatSpace Radiation Can Enhance the TGFβ InducedEpithelial-Mesenchymal Transitionion can enhance TGFβ induced EMT and cross-talk with ATM pathways  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation Can Enhance the TGFβ Induced Radiation Can Enhance the TGFβ Induced Epithelial-Mesenchymal Transition Minli Wang 1 , Megumi Hada 1 , Janice Huff 1 , Janice M. Pluth 2 , Jennifer Anderson 3 , Peter O'Neill 3 and Francis A. Cucinotta 4 1 USRA Division of Life Sciences, Houston TX USA; 2 Lawrence Berkeley National Laboratory, Berkeley CA, USA, 3 Gray Institute for Radiation Oncology & Biology, University of Oxford, UK, 4 NASA, Lyndon B. Johnson Space Center, Houston TX, USA TGFβ is a key modulator of the Epithelial-Mesenchymal Transition (EMT), important in cancer progression and metastasis, which involve classic Smad or non-Smad signaling pathways, leading to the suppression of epithelial genes and promoted expression of mesenchymal proteins. Ionizing radiation was found to specifically induce expression of

93

Patterns of radiotherapy practice for biliary tract cancer in Japan: results of the Japanese radiation oncology study group (JROSG) survey  

Science Journals Connector (OSTI)

The patterns of radiotherapy (RT) practice for biliary tract cancer (BTC) in Japan are not clearly established.

Fumiaki Isohashi; Kazuhiko Ogawa; Hirobumi Oikawa; Hiroshi Onishi…

2013-04-01T23:59:59.000Z

94

Changes in Gene Expression Predicting Local Control in Cervical Cancer: Results from Radiation Therapy Oncology Group 0128  

Science Journals Connector (OSTI)

...whether response at the intermediate dose is midway between those at the low and high doses...whether mutation frequency for ATAG is midway between mutation frequencies for AAAG...response at the intermediate dose was about midway between the responses at the low and high...

Joanne B. Weidhaas; Shu-Xia Li; Kathryn Winter; Janice Ryu; Anuja Jhingran; Bridgette Miller; Adam P. Dicker; David Gaffney

2009-06-15T23:59:59.000Z

95

Radiation dosimeter  

DOE Patents (OSTI)

A radiation detector readout circuit is provided which produces a radiation dose-rate readout from a detector even though the detector output may be highly energy dependent. A linear charge amplifier including an output charge pump circuit amplifies the charge signal pulses from the detector and pumps the charge into a charge storage capacitor. The discharge rate of the capacitor through a resistor is controlled to provide a time-dependent voltage which when integrated provides an output proportional to the dose-rate of radiation detected by the detector. This output may be converted to digital form for readout on a digital display.

Fox, Richard J. (Oak Ridge, TN)

1983-01-01T23:59:59.000Z

96

Radiation dosimeter  

DOE Patents (OSTI)

A radiation detector readout circuit is provided which produces a radiation dose-rate readout from a detector even through the detector output may be highly energy dependent. A linear charge amplifier including an output charge pump circuit amplifies the charge signal pulses from the detector and pumps the charge into a charge storage capacitor. The discharge rate of the capacitor through a resistor is controlled to provide a time-dependent voltage which when integrated provides an output proportional to the dose-rate of radiation detected by the detector. This output may be converted to digital form for readout on a digital display.

Fox, R.J.

1981-09-01T23:59:59.000Z

97

Appendix G. Radiation Appendix G. Radiation  

E-Print Network (OSTI)

-made sources. People are exposed to naturally occurring radiation constantly. For example, cosmic radiation of radiation and its effects on the environment and biological systems. Radiation comes from natural and humanAppendix G. Radiation #12;#12;Appendix G. Radiation This appendix presents basic facts about

Pennycook, Steve

98

Low Dose Radiation Research Program: Role of TNF-α as a Potential  

NLE Websites -- All DOE Office Websites (Extended Search)

Role of TNF-α as a Potential Signaling Mediator of Role of TNF-α as a Potential Signaling Mediator of Radiation-Induced Bystander Effect in Human Vascular Cells. Authors: Mohan Natarajan, Sumathy Mohan, Catherine Gibbons, Yan Bo and Munira A. Kadhim Institutions: Departments of Radiation Oncology and Pathology, University of Texas Health Science Center, San Antonio, Texas; Environmental Toxicology Graduate Program, University of California, Riverside; Radiation and Genomic Stability Unit, Medical research Council, Oxford, United Kingdom Identifying reliable and sensitive signaling pathways that are implicated in adverse health effects after exposure to low doses of ionizing radiation would allow us to understand the scientific basis of low dose-induced signaling pathways and their downstream phenotypic expression. This

99

Disrupted epithelial morphogenesis and aberrant lineage commitment following radiation and TGFβ  

NLE Websites -- All DOE Office Websites (Extended Search)

Disrupted epithelial morphogenesis and aberrant lineage Disrupted epithelial morphogenesis and aberrant lineage commitment following radiation and TGFβ I. Fernandez-Garcia and M.H. Barcellos-Hoff Department of Radiation Oncology, New York University School of Medicine, NY. In the present study, we evaluated cell lineage plasticity and its phenotypic effects in the non-malignant human mammary epithelial cell line MCF10A in response to ionizing radiation and TGFβ. We have recently shown that the molecular profiles of mammary tumors and normal mammary gland from irradiated mice are distinct from those arising in unirradiated mice by virtue of enriched stem cell and progenitor markers. Consistent with this, we found that radiation (10-100 cGy) increases the mammary repopulation capacity in a functional and marker assays (Nguyen et al. Cancer Cell

100

Low Dose Radiation Research Program: Using a Low LET Electron Microbeam to  

NLE Websites -- All DOE Office Websites (Extended Search)

Using a Low LET Electron Microbeam to Investigate Non-Targeted Using a Low LET Electron Microbeam to Investigate Non-Targeted Effects of Low Dose Radiation Authors: William F. Morgan1 and Marianne B. Sowa2 Institutions: 1Radiation Oncology Research Laboratory, University of Maryland, Baltimore, Maryland; 2Chemical Structure and Dynamics, Pacific Northwest National Laboratory, Richland Washington We have recently installed a low-linear energy transfer (LET) electron microbeam that generates energetic electrons to mimic radiation damage from gamma- and x-ray sources. It has been designed such that high-energy electrons deposit energy in a pre-selected subset of cells, leaving neighboring cells unirradiated (Figure 1). In this way it is possible to examine non-targeted effects associated with low dose radiation exposure,

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101

Radiation receiver  

DOE Patents (OSTI)

The apparatus for collecting radiant energy and converting same to alternate energy form includes a housing having an interior space and a radiation transparent window allowing, for example, solar radiation to be received in the interior space of the housing. Means are provided for passing a stream of fluid past said window and for injecting radiation absorbent particles in said fluid stream. The particles absorb the radiation and because of their very large surface area, quickly release the heat to the surrounding fluid stream. The fluid stream particle mixture is heated until the particles vaporize. The fluid stream is then allowed to expand in, for example, a gas turbine to produce mechanical energy. In an aspect of the present invention properly sized particles need not be vaporized prior to the entrance of the fluid stream into the turbine, as the particles will not damage the turbine blades. In yet another aspect of the invention, conventional fuel injectors are provided to inject fuel into the fluid stream to maintain the proper temperature and pressure of the fluid stream should the source of radiant energy be interrupted. In yet another aspect of the invention, an apparatus is provided which includes means for providing a hot fluid stream having hot particles disbursed therein which can radiate energy, means for providing a cooler fluid stream having cooler particles disbursed therein, which particles can absorb radiant energy and means for passing the hot fluid stream adjacent the cooler fluid stream to warm the cooler fluid and cooler particles by the radiation from the hot fluid and hot particles. 5 figs.

Hunt, A.J.

1983-09-13T23:59:59.000Z

102

Radiation Protection Act (Pennsylvania)  

Energy.gov (U.S. Department of Energy (DOE))

This Act combines the radiation safety provisions of The Atomic Energy Development and Radiation Control Act and the Environmental Radiation Protection Act, and empowers the Department of...

103

Radiation protection: Natural radiation risks  

Science Journals Connector (OSTI)

... radiation to which humans are exposed consists of four components - cosmic, gamma, internal, radon. The relative contribution that each makes to the sum is shown in the chart. ... but exposure of the whole body to terrestrial gamma rays and of the lungs to radon daughters are influenced by the nature and location of housing. Gamma rays are emitted ...

M. C. O'Riordan

1983-11-17T23:59:59.000Z

104

Quantitative, non-invasive imaging of radiation-induced DNA double strand breaks in vivo  

NLE Websites -- All DOE Office Websites (Extended Search)

Quantitative, non-invasive imaging of radiation-induced DNA double strand breaks in vivo Quantitative, non-invasive imaging of radiation-induced DNA double strand breaks in vivo Wenrong Li 1, , Fang Li 1 , Qian Huang 1 , Jingping Shen 1 , Frank Wolf 1 , Yujun He 1 , Xinjian Liu 1 , Y. Angela Hu 1 , Joel. S. Bedford 5 , and Chuan-Yuan Li 1,2,* Departments of 1 Radiation Oncology, 2 Pharmacology, University of Colorado School of Medicine, Aurora, Colorado, USA; 3 Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, USA DNA double strand breaks are a major form of DNA damage and a key mechanism through which radiotherapy and some chemotherapeutic agents kill cancer cells. Despite its importance, measuring DNA double strand breaks is still a tedious task that is normally carried out by gel electrophoresis or immunofluorescence staining. Here we report a novel approach to image and

105

European Integrated Project RISC-RAD Radiosensitivity of Individuals and Susceptibility to Cancer induced by Ionizing Radiations  

NLE Websites -- All DOE Office Websites (Extended Search)

Integrated Project RISC-RAD Integrated Project RISC-RAD Radiosensitivity of Individuals and Susceptibility to Cancer induced by Ionizing Radiations Laure Sabatier 1 , L.H.F Mullenders 2 , Mike Atkinson 3 , Simon Bouffler 4 , Herwig Paretzke 5 1 Laboratory of Radiobiology and Oncology, CEA, 18 route du panorama BP6 92265 Fontenay-aux- Roses, France 2 LUMC, Department of Toxicogenetics, Postal Zone S-4-P, P.O. Box 9600, 2300 RC Leiden, The Netherlands 3 GSF- Institute of Pathology, Ingolstädter Landstrasse 1, 85764 Neuherberg Germany 4 HPA Radiation Protection Division, Centre for Radiation Chemical and Environmental Hazards, Chilton, UK 5 GSF- Institute of Radiation Protection, Ingolstädter Landstrasse 1, Neuherberg, D-85764 Germany In radiological protection, the risks of inducing stochastic health effects (largely cancer) by a

106

The use of zeolites to generate PET phantoms for the validation of quantification strategies in oncology  

SciTech Connect

Purpose: In recent years, segmentation algorithms and activity quantification methods have been proposed for oncological {sup 18}F-fluorodeoxyglucose (FDG) PET. A full assessment of these algorithms, necessary for a clinical transfer, requires a validation on data sets provided with a reliable ground truth as to the imaged activity distribution, which must be as realistic as possible. The aim of this work is to propose a strategy to simulate lesions of uniform uptake and irregular shape in an anthropomorphic phantom, with the possibility to easily obtain a ground truth as to lesion activity and borders. Methods: Lesions were simulated with samples of clinoptilolite, a family of natural zeolites of irregular shape, able to absorb aqueous solutions of {sup 18}F-FDG, available in a wide size range, and nontoxic. Zeolites were soaked in solutions of {sup 18}F-FDG for increasing times up to 120 min and their absorptive properties were characterized as function of soaking duration, solution concentration, and zeolite dry weight. Saturated zeolites were wrapped in Parafilm, positioned inside an Alderson thorax-abdomen phantom and imaged with a PET-CT scanner. The ground truth for the activity distribution of each zeolite was obtained by segmenting high-resolution finely aligned CT images, on the basis of independently obtained volume measurements. The fine alignment between CT and PET was validated by comparing the CT-derived ground truth to a set of zeolites' PET threshold segmentations in terms of Dice index and volume error. Results: The soaking time necessary to achieve saturation increases with zeolite dry weight, with a maximum of about 90 min for the largest sample. At saturation, a linear dependence of the uptake normalized to the solution concentration on zeolite dry weight (R{sup 2}= 0.988), as well as a uniform distribution of the activity over the entire zeolite volume from PET imaging were demonstrated. These findings indicate that the {sup 18}F-FDG solution is able to saturate the zeolite pores and that the concentration does not influence the distribution uniformity of both solution and solute, at least at the trace concentrations used for zeolite activation. An additional proof of uniformity of zeolite saturation was obtained observing a correspondence between uptake and adsorbed volume of solution, corresponding to about 27.8% of zeolite volume. As to the ground truth for zeolites positioned inside the phantom, the segmentation of finely aligned CT images provided reliable borders, as demonstrated by a mean absolute volume error of 2.8% with respect to the PET threshold segmentation corresponding to the maximum Dice. Conclusions: The proposed methodology allowed obtaining an experimental phantom data set that can be used as a feasible tool to test and validate quantification and segmentation algorithms for PET in oncology. The phantom is currently under consideration for being included in a benchmark designed by AAPM TG211, which will be available to the community to evaluate PET automatic segmentation methods.

Zito, Felicia; De Bernardi, Elisabetta; Soffientini, Chiara; Canzi, Cristina; Casati, Rosangela; Gerundini, Paolo; Baselli, Giuseppe [Nuclear Medicine Department, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, via Francesco Sforza 35, 20122 Milan (Italy); Bioengineering Department, Politecnico di Milano, piazza Leonardo da Vinci 32, 20133 Milan (Italy) and Tecnomed Foundation, University of Milano-Bicocca, via Pergolesi 33, 20900 Monza (Italy); Bioengineering Department, Politecnico di Milano, piazza Leonardo da Vinci 32, 20133 Milan (Italy); Nuclear Medicine Department, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, via Francesco Sforza 35, 20122 Milan (Italy); Bioengineering Department, Politecnico di Milano, piazza Leonardo da Vinci 32, 20133 Milan (Italy)

2012-09-15T23:59:59.000Z

107

Prenatal X-ray Exposure and Rhabdomyosarcoma in Children: A Report from the Children's Oncology Group  

Science Journals Connector (OSTI)

...Napier ID. Reference doses for dental radiography. Br Dent J 1999...reduce gonadal radiation dose in dental radiology? Oral Surg Oral Med Oral Pathol...Jones GA, Burton EL. E-Speed dental film, time to take a new look...

Seymour Grufferman; Frederick Ruymann; Simona Ognjanovic; Erik B. Erhardt; and Harold M. Maurer

2009-04-01T23:59:59.000Z

108

Radiating gravastars  

SciTech Connect

Considering a Vaidya exterior spacetime, we study dynamical models of prototype gravastars, made of an infinitely thin spherical shell of a perfect fluid with the equation of state p = ?, enclosing an interior de Sitter spacetime. We show explicitly that the final output can be a black hole, an unstable gravastar, a stable gravastar or a 'bounded excursion' gravastar, depending on how the mass of the shell evolves in time, the cosmological constant and the initial position of the dynamical shell. This work presents, for the first time in the literature, a gravastar that emits radiation.

Chan, R. [Coordenação de Astronomia e Astrofísica, Observatório Nacional, Rua General José Cristino, 77, São Cristóvão 20921-400, Rio de Janeiro, RJ (Brazil); Silva, M.F.A. da [Departamento de Física Teórica, Instituto de Física, Universidade do Estado do Rio de Janeiro, Rua São Francisco Xavier 524, Maracanã 20550-900, Rio de Janeiro - RJ (Brazil); Rocha, Jaime F. Villas da [Instituto de Biociências, Departamento de Ciências Naturais, Universidade Federal do Estado do Rio de Janeiro, Av. Pasteur 458, Urca, CEP 22290-240, Rio de Janeiro, RJ (Brazil); Wang, Anzhong, E-mail: chan@on.br, E-mail: mfasnic@gmail.com, E-mail: jfvroch@pq.cnpq.br, E-mail: anzhong_wang@baylor.edu [GCAP-CASPER, Department of Physics, Baylor University, Waco, TX 76798 (United States)

2011-10-01T23:59:59.000Z

109

Natural and Radiation Carcinogenesis in Man. III. Radiation Carcinogenesis  

Science Journals Connector (OSTI)

...mice. NATURAL AND RADIATION CARCINOGENESIS IN MAN. 3. RADIATION CARCINOGENESIS. | Journal Article | Japan Neoplasms etiology Neoplasms, Radiation-Induced Radiation Genetics | JAPAN NEOPLASM ETIOLOGY NEOPLASMS, RADIATION-INDUCED RADIATION...

1965-01-01T23:59:59.000Z

110

Adaptors for radiation detectors  

DOE Patents (OSTI)

Described herein are adaptors and other devices for radiation detectors that can be used to make accurate spectral measurements of both small and large bulk sources of radioactivity, such as building structures, soils, vessels, large equipment, and liquid bodies. Some exemplary devices comprise an adaptor for a radiation detector, wherein the adaptor can be configured to collimate radiation passing through the adapter from an external radiation source to the radiation detector and the adaptor can be configured to enclose a radiation source within the adapter to allow the radiation detector to measure radiation emitted from the enclosed radiation source.

Livesay, Ronald Jason

2014-04-22T23:59:59.000Z

111

Radiation Safety  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Brotherhood of Locomotive Brotherhood of Locomotive Engineers & Trainmen Scott Palmer BLET Radiation Safety Officer New Hire Training New Hire study topics * GCOR * ABTH * SSI * Employee Safety * HazMat * Railroad terminology * OJT * 15-week class * Final test Hazardous Materials * Initial new-hire training * Required by OSHA * No specified class length * Open book test * Triennial module Locomotive Engineer Training A little bit older...a little bit wiser... * Typically 2-4 years' seniority * Pass-or-get-fired promotion * Intensive program * Perpetually tested to a higher standard * 20 Weeks of training * 15 of that is OJT * General Code of Operating Rules * Air Brake & Train Handling * System Special Instructions * Safety Instructions * Federal Regulations * Locomotive Simulators * Test Ride * Pass test with 90% Engineer Recertification

112

Nuclear radiation electronic gear  

Science Journals Connector (OSTI)

Nuclear radiation electronic gear ... Examines the line of nuclear radiation instrumentation offered by Nuclear-Chicago Corporation and Victoreen Instrument Company. ... Nuclear / Radiochemistry ...

S. Z. Lewin

1961-01-01T23:59:59.000Z

113

Radiation Control (Virginia)  

Energy.gov (U.S. Department of Energy (DOE))

The Department of Health is responsible for regulating radiation and radioactive materials in the Commonwealth of Virginia. Although the Department's Radiation Control Program primarily focuses on...

114

National Medical Care System May Impede Fostering of True Specialization of Radiation Oncologists: Study Based on Structure Survey in Japan  

Science Journals Connector (OSTI)

Purpose To evaluate the actual work environment of radiation oncologists (ROs) in Japan in terms of working pattern, patient load, and quality of cancer care based on the relative time spent on patient care. Methods and Materials In 2008, the Japanese Society of Therapeutic Radiology and Oncology produced a questionnaire for a national structure survey of radiation oncology in 2007. Data for full-time \\{ROs\\} were crosschecked with data for part-time \\{ROs\\} by using their identification data. Data of 954 \\{ROs\\} were analyzed. The relative practice index for patients was calculated as the relative value of care time per patient on the basis of Japanese Blue Book guidelines (200 patients per RO). Results The working patterns of RO varied widely among facility categories. \\{ROs\\} working mainly at university hospitals treated 189.2 patients per year on average, with those working in university hospitals and their affiliated facilities treating 249.1 and those working in university hospitals only treating 144.0 patients per year on average. The corresponding data were 256.6 for cancer centers and 176.6 for other facilities. Geographically, the mean annual number of patients per RO per quarter was significantly associated with population size, varying from 143.1 to 203.4 (p Japan appear to be problematic for fostering true specialization of radiation oncologists.

Hodaka Numasaki; Hitoshi Shibuya; Masamichi Nishio; Hiroshi Ikeda; Kenji Sekiguchi; Norihiko Kamikonya; Masahiko Koizumi; Masao Tago; Yutaka Ando; Nobuhiro Tsukamoto; Atsuro Terahara; Katsumasa Nakamura; Michihide Mitsumori; Tetsuo Nishimura; Masato Hareyama; Teruki Teshima

2012-01-01T23:59:59.000Z

115

Low Dose Radiation Research Program: Comparisons of IR and ROS for  

NLE Websites -- All DOE Office Websites (Extended Search)

Comparisons of IR and ROS for Induction of Damage to Cells Comparisons of IR and ROS for Induction of Damage to Cells Kathryn D. Held1, Yvonne L. McCarey1, Laurence Tartier1, Elena V. Rusyn1, Giuseppe Schettino2, Melvyn Folkard2, Kevin M. Prise2, and Barry D. Michael2 1Department of Radiation Oncology, Massachusetts General Hospital/Harvard Medical School, Boston, MA 02114; 2Gray Laboratory Cancer Research Trust, Mount Vernon Hospital, Northwood, HA6 2JR, UK Accurate evaluation of the risks associated with exposure to low doses of ionizing radiation (IR) is a major challenge for environmental sciences. Studies on the mechanisms of the actions of low doses of IR are needed to help understand possible risks. IR exerts its effects on cells through production of reactive oxidizing species (ROS) such as ·OH, H2O2 and

116

Choice of a control group for oncology randomized control trials (RCTs): Balancing requirements for clinical value, validity, and efficiency with protection of human subjects.  

Science Journals Connector (OSTI)

...patients with advanced ovarian cancer (AOC) and 2) develop a framework for analyzing...for oncology RCTs. METHODS: We reviewed AOC RCTs during the past 3 decades regarding...search for a standard regimen for treating AOC has been highlighted by controversies regarding...

Ying Ying Yu and Henry Silverman

2006-04-15T23:59:59.000Z

117

Low Dose Radiation Program: Radiation Biology and the Radiation Research  

NLE Websites -- All DOE Office Websites (Extended Search)

Biology and the Radiation Research Program Biology and the Radiation Research Program The Department of Energy (DOE) and its predecessor organizations, Energy Research and Development Agency (ERDA) and Atomic Energy Commission (AEC), always have been concerned about the health effects of ionizing radiation. Extensive research has been conducted under their sponsorship at all levels of biological organization from molecules to man. Over the past 60 years, studies using every type of radiation source have included exposure to both external radiation sources and to internally deposited radioactive materials. These exposures used different dose patterns and distributions delivered over a wide range of experimental times. This extensive research provided the basis for the new Low Dose Radiation Research Program, linking

118

radiation.p65  

Office of Legacy Management (LM)

5 5 United States Department of Energy This fact sheet explains the potential health hazards associated with the radioactive decay of uranium and other radioactive elements found in ore and mill tailings. Potential Health Hazards of Radiation Man-made sources of radiation, most notably from medical uses and consumer products, contribute to the remaining radiation dose that individuals receive. A few household products, including smoke detectors, micro- wave ovens, and color televisions, emit small amounts of radiation. For most people, the benefits from using such products far outweigh the radiation risks. Radiation Dose Radiation is measured in various units. Individuals who have been exposed to radiation have received a radiation dose. Radiation dose to people is expressed in

119

Radiation Protection and Safety Training | Environmental Radiation...  

NLE Websites -- All DOE Office Websites (Extended Search)

The objective of this course is to provide students with an introduction to the fundamentals of ionizing radiation protection and safety. The course curriculum combines...

120

Atmospheric Radiation Measurement Radiative Atmospheric Divergence...  

NLE Websites -- All DOE Office Websites (Extended Search)

radiation emitted by the earth. This instrument is onboard a European Union geostationary weather satellite launched in December 2005; it is collecting data over Niamey and the...

Note: This page contains sample records for the topic "radiation oncology feinberg" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


121

radiation.cdr  

Office of Legacy Management (LM)

Radiation-It's a Fact of Life Radiation-It's a Fact of Life It has been with us since the beginning of time. Everyone who has ever walked on this planet has been exposed to radiation. For the most part, nature is the largest source of exposure. It's in the air we breathe, the ground we walk on, and even the food we eat. The radiation we receive from all natural and some man-made sources is called "background radiation." The millirem (mrem) is a unit used for measuring radiation received by a person. The total average background for radiation received by people living in the United States is 360 millirem per year (mrem/yr), of which 300 mrem/yr is from natural sources, and 60 mrem/yr is man-made. Cosmic Radiation from the sun and stars Internal Radiation from naturally radioactive

122

Plutonium radiation surrogate  

DOE Patents (OSTI)

A self-contained source of gamma-ray and neutron radiation suitable for use as a radiation surrogate for weapons-grade plutonium is described. The source generates a radiation spectrum similar to that of weapons-grade plutonium at 5% energy resolution between 59 and 2614 keV, but contains no special nuclear material and emits little .alpha.-particle radiation. The weapons-grade plutonium radiation surrogate also emits neutrons having fluxes commensurate with the gamma-radiation intensities employed.

Frank, Michael I. (Dublin, CA)

2010-02-02T23:59:59.000Z

123

Radiation Safety Program Annual Review  

E-Print Network (OSTI)

........................................................................10 AREA RADIATION SURVEYS AND CONTAMINATION CONTROL...........................................11.....................................................................................................13 RADIOACTIVE WASTE MANAGEMENT meetings of the Radiation Safety Committee where new users and uses of radioactive materials, radiation

Lyubomirsky, Ilya

124

Radiator Labs | Department of Energy  

NLE Websites -- All DOE Office Websites (Extended Search)

of steam buildings. Radiator Labs developed a mechanism that allows heating systems to control heat transfer at each radiator. The Radiator Labs design utilizes an...

125

The universal radiative transport equation  

E-Print Network (OSTI)

THE UNIVERSAL RADIATIVE TRANSPORT EQUATION Rudolph W.The Universal Radiative Transport Equation Rudolph W.The various radiative transport equations used in general

Preisendorfer, Rudolph W

1959-01-01T23:59:59.000Z

126

Radiation Dose Estimates from  

E-Print Network (OSTI)

Summary: Radiation Dose Estimates from Hanford Radioactive Material Releases to the Air- tantly, what radiation dose people may have received. An independent Technical Steering Panel (TSP, additionalProjectworkcouldresultin revisions of these dose estimates. April 21, 1994 Companion

127

Maryland Radiation Act (Maryland)  

Energy.gov (U.S. Department of Energy (DOE))

The policy of the state is to provide for the constructive use of radiation and control radiation emissions. This legislation authorizes the Department of the Environment to develop comprehensive...

128

WI Radiation Protection  

Energy.gov (U.S. Department of Energy (DOE))

This statute seeks to regulate radioactive materials, to encourage the constructive uses of radiation, and to prohibit and prevent exposure to radiation in amounts which are or may be detrimental...

129

RADIONUCLIDE RADIATION PROTECTION  

E-Print Network (OSTI)

COPYRIGHT 2002 Nuclear Technology Publishing #12;3 #12;4 #12;5 Radiation Protection Dosimetry Vol. 98, No'Energie Atomique, CEA/Saclay, France ISBN 1 870965 87 6 RADIATION PROTECTION DOSIMETRY Vol. 98 No 1, 2002 Published by Nuclear Technology Publishing #12;RADIONUCLIDE AND RADIATION PROTECTION DATA HANDBOOK 2nd Edition (2002

Healy, Kevin Edward

130

The Circadian Rhythm, A Continuous Transcription-Translation Feedback Loop, Contributes to Low-Dose Radiation-Induced Radioadaptive Response  

NLE Websites -- All DOE Office Websites (Extended Search)

The Circadian Rhythm, A Continuous Transcription-Translation Feedback Loop, Contributes to Low-Dose Radiation-Induced Radioadaptive Response Aris Alexandrou and Jian Jian Li Department of Radiation Oncology, the University of California Davis, Sacramento, California, 95817 The initiation of the circadian rhythm field occurred when the Takahashi group defined a mutation in the mouse gene "Clock" and cloned the circadian locomotor output cycles kaput (Clock) in the mid- 1990's (1-3). Currently more than a dozen clock genes have been identified (3-4). Disruptions in the circadian rhythm via changes in environmental conditions, such as, diet, temperature, and night/day hours lead to the pathogenesis of a multitude of diseases, such as, cancer, diabetes mellitus,

131

Radioactivity and Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Radioactivity and Radiation Radioactivity and Radiation Uranium and Its Compounds line line What is Uranium? Chemical Forms of Uranium Properties of Uranium Compounds Radioactivity and Radiation Uranium Health Effects Radioactivity and Radiation Discussion of radioactivity and radiation, uranium and radioactivity, radiological health risks of uranium isotopes and decay products. Radioactivity Radioactivity is the term used to describe the natural process by which some atoms spontaneously disintegrate, emitting both particles and energy as they transform into different, more stable atoms. This process, also called radioactive decay, occurs because unstable isotopes tend to transform into a more stable state. Radioactivity is measured in terms of disintegrations, or decays, per unit time. Common units of radioactivity

132

SHP-2 tyrosine phosphate-dependent focal adhesion kinase mediated cell migration of primary endothelial cells upon low LET radiation exposure  

NLE Websites -- All DOE Office Websites (Extended Search)

SHP-2 tyrosine phosphate-dependent focal adhesion kinase mediated cell SHP-2 tyrosine phosphate-dependent focal adhesion kinase mediated cell migration of primary endothelial cells upon low LET radiation exposure Xiangpeng Zheng, 1 Sumathy Mohan, 3 and Mohan Natarajan 1,2 Departments of 1 Otolaryngology, 2 Radiation Oncology, and 3 Pathology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 The influence and mechanism of low LET radiation exposure on wound healing process is not yet fully understood. Based on the vital role of endothelial cells in migration and wound healing, this study investigated the response of endothelial cells to low-dose irradiation and the underlying mechanism. A wound was inflicted in the confluent monolayer of primary vascular endothelial cells exposing a cell-free zone on the plate. The cells were then exposed

133

TERSat: Trapped Energetic Radiation Satellite  

E-Print Network (OSTI)

Radiation damage caused by interactions with high-energy particles in the Van Allen Radiation Belts is a leading

Clements, Emily B.

2012-01-01T23:59:59.000Z

134

Americans' Average Radiation Exposure  

SciTech Connect

We live with radiation every day. We receive radiation exposures from cosmic rays, from outer space, from radon gas, and from other naturally radioactive elements in the earth. This is called natural background radiation. It includes the radiation we get from plants, animals, and from our own bodies. We also are exposed to man-made sources of radiation, including medical and dental treatments, television sets and emission from coal-fired power plants. Generally, radiation exposures from man-made sources are only a fraction of those received from natural sources. One exception is high exposures used by doctors to treat cancer patients. Each year in the United States, the average dose to people from natural and man-made radiation sources is about 360 millirem. A millirem is an extremely tiny amount of energy absorbed by tissues in the body.

NA

2000-08-11T23:59:59.000Z

135

Radiation: Facts, Risks and Realities  

E-Print Network (OSTI)

of Radiation 3 Understanding Radiation Risks 6 Naturally Occurring (Background) Radiation 7 Man-Made Radiation, beta particles and gamma rays. Other types, such as x-rays, can occur naturally or be machine-produced. Scientists have also learned that radiation sources are naturally all around us. Radiation can come from

136

Departments of Basic Oncology, Preventive Oncology and  

E-Print Network (OSTI)

Malignant melanoma is one of the most rapidly increasing cancer types, and patients with metastatic disease have a very poor prognosis. Detection of metastatic melanoma cells in circulation may aid the clinician in assessing tumor progression, metastatic potential, and response to therapy. Tyrosinase is a key enzyme in melanine biosynthesis. The gene is actively expressed in melanocytes and melanoma cells. Melan A is a differentiation antigen that is expressed in melanocytes. The presence of these molecules in blood is considered a marker for circulating melanoma cells. In this study, we analyzed the usefulness of this marker combination in evaluating the response to therapy in the blood of 30 patients with malignant melanoma. Circulating cells were detected by a reverse-transcriptasepolymerase-chain reaction. The tyrosinase expression was observed in 9 (30%) patients and Melan A in 19 (63.3%) patients before therapy. Following treatment, the tyrosinase mRNA was detected in only one patient, while Melan A transcripts were still present in 14 patients. We suggest that this molecular assay can identify circulating melanoma cells that express melanoma-associated antigens and may provide an early indication of therapy effectiveness.

Ozlem Bitisik; Hakan Camlica; Derya Duranyildiz; Faruk Tas; Sidika Kurul; Nejat Dalay

2002-01-01T23:59:59.000Z

137

Low dose radiation effects of multipotent neural stem and progenitor cells  

NLE Websites -- All DOE Office Websites (Extended Search)

effects of multipotent neural stem and progenitor cells effects of multipotent neural stem and progenitor cells Charles L. Limoli, Department of Radiation Oncology, University of California, Irvine 92697-2695 Multipotent neural cells (both stem cells and their precursor cell progeny) retain their capacity to proliferate and differentiate throughout the mammalian lifespan. High numbers of these cells are located within the dentate subgranular zone (SGZ) of the hippocampus and the subventricular (SVZ) zone adjacent to the lateral ventricles, where they produce cells that can migrate away and differentiate into neurons (neurogenesis) and glia (gliogenesis). The realization that the brain contains such cells has sparked intense interest and speculation regarding their potential function. While significant data

138

Low Dose Radiation Research Program: Real-time Study of Signal Transduction  

NLE Websites -- All DOE Office Websites (Extended Search)

Real-time Study of Signal Transduction Pathways Involving in Real-time Study of Signal Transduction Pathways Involving in Bystander Effects Using Single Nanoparticle Optics and Single Living Cell Imaging Authors: Prakash D. Nallathamby, X. Nancy Xu, Mohan Natarajan Institutions: Department of Chemistry and Biochemistry, Old Dominion University, Norfolk, Virginia and Department of Radiation Oncology, The University of Texas Health Science Center, San Antonio, Texas The mechanisms of bystander effects remain largely unknown. Bystander responses are thought to depend on activation of cellular communication processes. Recent studies have speculated that several crucial signal transduction pathways could play a major role in bystander effects. These crucial signal transduction pathways are controlled by a coordinated

139

Impact of Quality Assurance Rounds in a Canadian Radiation Therapy Department  

SciTech Connect

Purpose: Quality assurance (QA) programs aim to identify inconsistencies that may compromise patient care. Radiation treatment planning is a well-documented source of variation in radiation oncology, leading many organizations to recommend the implementation of QA rounds in which radiation therapy plans are peer reviewed. This study evaluates the outcome of QA rounds that have been conducted by a radiation therapy department since 2004. Methods and Materials: Prospectively documented records of QA rounds, from 2004 to 2010, were obtained. During rounds, randomly selected radiation therapy plans were peer reviewed and assigned a grade of A (adequate), B (minor suggestions of change to a plan for a future patient), or C (significant change required before the next fraction). The proportion of plans that received each recommendation was calculated, and the relationship between recommendations for each plan, tumor site, and mean years of experience of the radiation oncologist (RO) were explored. Chart reviews were performed for each plan that received a C. Results: During the study period, 1247 plans were evaluated; 6% received a B and 1% received a C. The mean RO years of experience were lower for plans graded C versus those graded A (P=.02). The tumor sites with the highest proportion of plans graded B or C were gastrointestinal (14%), lung (13%), and lymphoma (8%). The most common reasons for plans to receive a grade of C were inadequate target volume coverage (36%), suboptimal dose or fractionation (27%), errors in patient setup (27%), and overtreatment of normal tissue (9%). Conclusions: This study demonstrated that QA rounds are feasible and an important element of a radiation therapy department's QA program. Through peer review, plans that deviate from a department's expected standard can be identified and corrected. Additional benefits include identifying patterns of practice that may contribute to inconsistencies in treatment planning and the continuing education of staff members who attend.

Lefresne, Shilo; Olivotto, Ivo A.; Joe, Howard; Blood, Paul A. [Radiotherapy Department, BC Cancer Agency, Vancouver Island Centre, Vancouver, British Columbia (Canada) [Radiotherapy Department, BC Cancer Agency, Vancouver Island Centre, Vancouver, British Columbia (Canada); Radiotherapy Department, University of British Columbia, Vancouver, British Columbia (Canada); Olson, Robert A., E-mail: rolson2@bccancer.bc.ca [Radiotherapy Department, University of British Columbia, Vancouver, British Columbia (Canada); Radiotherapy Department, BC Cancer Agency, Centre for the North, Prince George, British Columbia (Canada)

2013-03-01T23:59:59.000Z

140

Radiation physics, biophysics, and radiation biology  

SciTech Connect

Research at the Center for Radiological Research is a multidisciplenary blend of physics, chemistry and biology aimed at understanding the mechanisms involved in the health problems resulting from human exposure to ionizing radiations. The focus is increased on biochemistry and the application of the techniques of molecular biology to the problems of radiation biology. Research highlights of the program from the past year are described. A mathematical model describing the production of single-strand and double-strand breaks in DNA as a function radiation quality has been completed. For the first time Monte Carlo techniques have been used to obtain directly the spatial distribution of DNA moieties altered by radiation. This information was obtained by including the transport codes a realistic description of the electronic structure of DNA. We have investigated structure activity relationships for the potential oncogenicity of a new generation of bioreductive drugs that function as hypoxic cytotoxins. Experimental and theoretical investigation of the inverse dose rate effect, whereby medium LET radiations actually produce an c effect when the dose is protracted, is now at a point where the basic mechanisms are reasonably understood and the complex interplay between dose, dose rate and radiation quality which is necessary for the effect to be present can now be predicted at least in vitro. In terms of early radiobiological damage, a quantitative link has been established between basic energy deposition and locally multiply damaged sites, the radiochemical precursor of DNA double strand breaks; specifically, the spatial and energy deposition requirements necessary to form LMDs have been evaluated. For the first time, a mechanically understood biological fingerprint'' of high-LET radiation has been established. Specifically measurement of the ratio of inter-to intra-chromosomal aberrations produces a unique signature from alpha-particles or neutrons.

Hall, E.J.; Zaider, M.

1993-05-01T23:59:59.000Z

Note: This page contains sample records for the topic "radiation oncology feinberg" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


141

Atmospheric Radiation Measurement Program  

NLE Websites -- All DOE Office Websites (Extended Search)

3 3 ARM 2003 Tom Ackerman Chief Scientist Tom Ackerman Chief Scientist ARM ARM Atmospheric Radiation Measurement Atmospheric Radiation Measurement WARNING! WARNING! Today is April 1 But that has NO bearing on this message Today is April 1 But that has NO bearing on this message ARM ARM Atmospheric Radiation Measurement Atmospheric Radiation Measurement Two Topics Two Topics * Status of ARM (quick overview) * Science plan - ARM in the next 5 years * Status of ARM (quick overview) * Science plan - ARM in the next 5 years ARM ARM Atmospheric Radiation Measurement Atmospheric Radiation Measurement ARM Status - Science ARM Status - Science * Steadily increasing productivity - Poster session - over 220 posters (may need to do something about submissions next year) - Peer-reviewed articles: 2.5 to 3 per year per

142

The flying radiation case  

SciTech Connect

The Los Alamos foil implosion program has the goal of producing an intense, high-energy density x-ray source by converting the energy of a magnetically imploded plasma into radiation and material energy. One of the methods for converting the plasma energy into thermal energy and radiation and utilizing it for experiments is called the flying radiation case (FRC). In this paper the authors shall model the FRC and provide a physical description of the processes involved. An analytic model of a planar FRC in the hydrodynamic approximation is used to describe the assembly and shock heating of a central cushion by a conducting liner driver. The results are also used to benchmark a hydrodynamics code for modeling an FRC. They then use a radiation-hydrodynamics computational model to explore the effects of radiation production and transport when a gold plasma assembles on a CH cushion. Results are presented for the structure and evolution of the radiation hohlraum.

Brownell, J.H.; Bowers, R.L. [Los Alamos National Lab., NM (United States). Applied Theoretical and Computational Physics Div.

1997-04-01T23:59:59.000Z

143

RHOBOT: Radiation hardened robotics  

SciTech Connect

A survey of robotic applications in radioactive environments has been conducted, and analysis of robotic system components and their response to the varying types and strengths of radiation has been completed. Two specific robotic systems for accident recovery and nuclear fuel movement have been analyzed in detail for radiation hardness. Finally, a general design approach for radiation-hardened robotics systems has been developed and is presented. This report completes this project which was funded under the Laboratory Directed Research and Development program.

Bennett, P.C.; Posey, L.D. [Sandia National Labs., Albuquerque, NM (United States)

1997-10-01T23:59:59.000Z

144

Atomic Radiation (Illinois)  

Energy.gov (U.S. Department of Energy (DOE))

This article states permissible levels of radiation in unrestricted areas, environmental standards for uranium fuel cycle and information about notification of incidents.

145

Radiation.cdr  

NLE Websites -- All DOE Office Websites (Extended Search)

An average American's exposure is about 620 millirems per year from naturally occurring and other sources. Other Factors Background radiation varies with location....

146

Radiation Hazards Program (Minnesota)  

Energy.gov (U.S. Department of Energy (DOE))

These regulations, promulgated by the Department of Health, set allowable radiation standards and mitigation practices, as well as procedures for the transportation of hazardous material.

147

Radiation Safety September 2013  

E-Print Network (OSTI)

...................................................................................... 8 2.6 RUA Holder........................................................................................................ 11 3.3 Radiation Use Authorization (RUA).......................................................................................... 11 3.4 Review of RUA Applications

California at Irvine, University of

148

Radiative polarization of electrons  

Science Journals Connector (OSTI)

We present a new method of calculating the radiative polarization of electrons in homogeneous magnetic fields, using the modified electron propagation function.

Julian Schwinger and Wu-yang Tsai

1974-03-15T23:59:59.000Z

149

Appendix F. Radiation Appendix F. Radiation F-3  

E-Print Network (OSTI)

from natural and human-made sources. People are exposed to naturally occurring radiation constantlyAppendix F. Radiation #12;#12;Appendix F. Radiation F-3 Appendix F. Radiation This appendix presents basic facts about radiation. The information is intended to be a basis for understanding

Pennycook, Steve

150

Appendix F: Radiation Appendix F: Radiation F-3  

E-Print Network (OSTI)

. People are exposed to naturally occurring radiation constantly. For example, cosmic radiation; radon effects on the environment and biological systems. Radiation comes from natural and human-made sourcesAppendix F: Radiation #12;#12;Appendix F: Radiation F-3 P P P E E E N NN HYDROGEN ATOM DEUTERIUM

Pennycook, Steve

151

Appendix F: Radiation Appendix F: Radiation F-3  

E-Print Network (OSTI)

to naturally occurring radiation constantly. For example, cosmic radiation; radon in air; potassium in food on the environment and biological systems. Radiation comes from natural and human-made sources. People are exposedAppendix F: Radiation #12;#12;Appendix F: Radiation F-3 Fig. F.1. The hydrogen atom and its

Pennycook, Steve

152

Appendix G. Radiation Appendix G. Radiation G-3  

E-Print Network (OSTI)

from natural and human-made sources. People are exposed to naturally occurring radiation constantlyAppendix G. Radiation #12;#12;Appendix G. Radiation G-3 Appendix G. Radiation This appendix presents basic facts about radiation. The information is intended to be a basis for un- derstanding

Pennycook, Steve

153

Appendix F. Radiation Appendix F. Radiation F-3  

E-Print Network (OSTI)

from natural and human-made sources. People are exposed to naturally occurring radiation constantlyAppendix F. Radiation #12;#12;Appendix F. Radiation F-3 Appendix F. Radiation This appendix presents basic facts about radiation. The information is intended to be a basis for un- derstanding

Pennycook, Steve

154

Radiation physics, biophysics, and radiation biology  

SciTech Connect

The following research programs from the Center for Radiological Research of Columbia University are described: Design and development of a new wall-less ultra miniature proportional counter for nanodosimetry; some recent measurements of ionization distributions for heavy ions at nanometer site sizes with a wall-less proportional counter; a calculation of exciton energies in periodic systems with helical symmetry: application to a hydrogen fluoride chain; electron energy-loss function in polynucleotide and the question of plasmon excitation; a non-parametric, microdosimetric-based approach to the evaluation of the biological effects of low doses of ionizing radiation; high-LET radiation risk assessment at medium doses; high-LET radiobiological effects: increased lesion severity or increased lesion proximity; photoneutrons generated by high energy medical linacs; the biological effectiveness of neutrons; implications for radiation protection; molecular characterization of oncogenes induced by neutrons; and the inverse dose-rate effect for oncogenic transformation by charged particles is LET dependent.

Hall, E.J.

1992-05-01T23:59:59.000Z

155

COLUMBIA UNIVERSITY Radiation Safety Program  

E-Print Network (OSTI)

DDE ESTIMATED DOSE FROM CONCEPTION TO DECLARATION: DDE Radiation Safety Officer Signature for increased protection from ionizing radiation for declared pregnant radiation workers. The radiation dose of the occupational dose limit of 50 mSv (5.0 rem). The CPMC Radiation Safety Office will provide education

Jia, Songtao

156

Radiation safety system  

Science Journals Connector (OSTI)

......occupational illness to personnel, major damage...acceptable levels. Selection of control measures...or equipment operating correctly in...99 103 to 104 Personnel life safety...and abnormal operating conditions under...radiation risk to personnel, public and...worker radiation training) reduces the......

Vaclav Vylet; James C. Liu; Lawrence S. Walker

2009-11-01T23:59:59.000Z

157

Radiation safety system  

Science Journals Connector (OSTI)

......disable this safety function and...circuits and software. Other required...source in case of radiation monitors. Feedback...from other non-safety systems to prevent...write and check software. The expected...logic systems for safety functions can...levels of prompt radiation hazard. ACS......

Vaclav Vylet; James C. Liu; Lawrence S. Walker

2009-11-01T23:59:59.000Z

158

Risks from ionizing radiation  

Science Journals Connector (OSTI)

... RADON indoors now accounts for nearly half of the average UK population exposure to ionizing radiation ... exposure to ionizing radiation. We believe that the extent of the variation in exposure to radon in the United Kingdom and else-where and its magnitude in relation to exposures from ...

R. H. Clarke; T. R. E. Southwood

1989-03-16T23:59:59.000Z

159

Nuclear radiation actuated valve  

DOE Patents (OSTI)

A nuclear radiation actuated valve for a nuclear reactor. The valve has a valve first part (such as a valve rod with piston) and a valve second part (such as a valve tube surrounding the valve rod, with the valve tube having side slots surrounding the piston). Both valve parts have known nuclear radiation swelling characteristics. The valve's first part is positioned to receive nuclear radiation from the nuclear reactor's fuel region. The valve's second part is positioned so that its nuclear radiation induced swelling is different from that of the valve's first part. The valve's second part also is positioned so that the valve's first and second parts create a valve orifice which changes in size due to the different nuclear radiation caused swelling of the valve's first part compared to the valve's second part. The valve may be used in a nuclear reactor's core coolant system.

Christiansen, David W. (Kennewick, WA); Schively, Dixon P. (Richland, WA)

1985-01-01T23:59:59.000Z

160

National Medical Care System May Impede Fostering of True Specialization of Radiation Oncologists: Study Based on Structure Survey in Japan  

SciTech Connect

Purpose: To evaluate the actual work environment of radiation oncologists (ROs) in Japan in terms of working pattern, patient load, and quality of cancer care based on the relative time spent on patient care. Methods and Materials: In 2008, the Japanese Society of Therapeutic Radiology and Oncology produced a questionnaire for a national structure survey of radiation oncology in 2007. Data for full-time ROs were crosschecked with data for part-time ROs by using their identification data. Data of 954 ROs were analyzed. The relative practice index for patients was calculated as the relative value of care time per patient on the basis of Japanese Blue Book guidelines (200 patients per RO). Results: The working patterns of RO varied widely among facility categories. ROs working mainly at university hospitals treated 189.2 patients per year on average, with those working in university hospitals and their affiliated facilities treating 249.1 and those working in university hospitals only treating 144.0 patients per year on average. The corresponding data were 256.6 for cancer centers and 176.6 for other facilities. Geographically, the mean annual number of patients per RO per quarter was significantly associated with population size, varying from 143.1 to 203.4 (p < 0.0001). There were also significant differences in the average practice index for patients by ROs working mainly in university hospitals between those in main and affiliated facilities (1.07 vs 0.71: p < 0.0001). Conclusions: ROs working in university hospitals and their affiliated facilities treated more patients than the other ROs. In terms of patient care time only, the quality of cancer care in affiliated facilities might be worse than that in university hospitals. Under the current national medical system, working patterns of ROs of academic facilities in Japan appear to be problematic for fostering true specialization of radiation oncologists.

Numasaki, Hodaka [Department of Medical Physics and Engineering, Osaka University Graduate School of Medicine, Suita, Osaka (Japan); Shibuya, Hitoshi [Department of Radiology, Tokyo Medical and Dental University, Tokyo (Japan); Nishio, Masamichi [Department of Radiology, National Hospital Organization Hokkaido Cancer Center, Sapporo, Hokkaido (Japan); Ikeda, Hiroshi [Department of Radiology, Sakai Municipal Hospital, Sakai, Osaka (Japan); Sekiguchi, Kenji [Department of Radiation Oncology, St. Luke's International Hospital, Tokyo (Japan); Kamikonya, Norihiko [Department of Radiology, Hyogo College of Medicine, Nishinomiya, Hyogo (Japan); Koizumi, Masahiko [Oncology Center, Osaka University Hospital, Suita, Osaka (Japan); Tago, Masao [Department of Radiology, Teikyo University School of Medicine University Hospital, Mizonokuchi, Kawasaki, Kanagawa (Japan); Ando, Yutaka [Department of Medical Informatics, Heavy Ion Medical Center, National Institute of Radiological Sciences, Chiba (Japan); Tsukamoto, Nobuhiro [Department of Radiation Oncology, Saitama Medical University International Medical Center, Saitama (Japan); Terahara, Atsuro [Department of Radiology, Toho University Omori Medical Center, Tokyo (Japan); Nakamura, Katsumasa [Department of Radiology, Kyushu University Hospital at Beppu, Oita (Japan); Mitsumori, Michihide [Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine Kyoto University, Kyoto (Japan); Nishimura, Tetsuo [Division of Radiation Oncology, Shizuoka Cancer Center, Shizuoka (Japan); Hareyama, Masato [Department of Radiology, Sapporo Medical University, Hokkaido (Japan); Teshima, Teruki, E-mail: teshima@sahs.med.osaka-u.ac.jp [Department of Medical Physics and Engineering, Osaka University Graduate School of Medicine, Suita, Osaka (Japan)

2012-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "radiation oncology feinberg" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


161

Radiation Weighting Factors and High Energy Radiation  

Science Journals Connector (OSTI)

......generally inadequate for high energy radiation. In order to determine...appropriate wR values in the high energy region, several criteria are...are proposed for neutrons of energy above 100 MeV and for protons above 10 MeV. The wR value for muons is confirmed to be practically......

M. Pelliccioni

1998-12-01T23:59:59.000Z

162

Radiation effects on humans  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation effects on humans Radiation effects on humans Name: Joe Kemna Location: N/A Country: N/A Date: N/A Question: I am trying to find information on radiation. I need the effects on humans, the damage it causes to the environment, and any extra information you might have on the subject. Thank you for your time. Replies: Your library should be a good place to start, but first you need to narrow your question a bit. "Radiation" means radio waves, heat, light (including the ultraviolet light that causes suntan and sunburn), and what's called "ionizing radiation." By far the major source of the first three is the Sun, while the last I believe comes principally from cosmic rays and various naturally radioactive elements like uranium and radon. The most significant manmade sources of exposure would --- I think --- be household wiring and appliances (radio), engines and heating devices (heat), lamps (light), and X-ray machines, flying at high altitude in airplanes, and living in well-insulated homes built over radon sources (ionizing radiation). Heat, light and ionizing radiation play vital roles in the ecology of the Earth. Radio, light (in particular "tanning" ultraviolet), and ionizing radiation have all been widely assumed at different times to be particularly good or particularly bad for human health. Some recent issues of public concern have been the effect of radio waves from electric transmission lines, the effect on skin cancer incidence from tanning and sunburns, the depletion of the ultraviolet-light-produced ozone in the upper atmosphere by chlorofluorocarbons (CFCs), "global warming" from the increased absorption of heat radiation from the surface by atmospheric carbon dioxide and methane, and the effect of a long exposure to low levels of ionizing radiation as for example the people of Eastern Europe are experiencing from the Chernobyl nuclear power plant accident.

163

Genomics-based early-phase clinical trials in oncology: Recommendations from the task force on Methodology for the Development of Innovative Cancer Therapies  

Science Journals Connector (OSTI)

Abstract The Methodology for the Development of Innovative Cancer Therapies (MDICT) task force discussed incorporation of genomic profiling into early (Phase I and II) clinical trials in oncology. The task force reviewed the challenges of standardising genomics data in a manner conducive to conducting clinical trials. Current barriers to successful and efficient implementation were identified and discussed, as well as the methods of genomic analysis, the proper setting for study and strategies to facilitate timely completion of genomics-based studies. The importance of properly capturing and cataloguing outcomes was also discussed. Several recommendations regarding the use of genomics in these trials are provided.

Stephen V. Liu; Vincent A. Miller; Marinus W. Lobbezoo; Giuseppe Giaccone

2014-01-01T23:59:59.000Z

164

Candidate Radiation Drugs Inch Forward  

Science Journals Connector (OSTI)

Candidate Radiation Drugs Inch Forward 10.1126/science.331.6024...radiation, workers at the damaged Fukushima nuclear plant wear protective gear...Candidate radiation drugs inch forward. | News | 0 (E)-4-carboxystyryl-4-chlorobenzylsulfone...

Yudhijit Bhattacharjee

2011-03-25T23:59:59.000Z

165

Developing Quality Assurance Processes for Image-Guided Adaptive Radiation Therapy  

SciTech Connect

Quality assurance has long been implemented in radiation treatment as systematic actions necessary to provide adequate confidence that the radiation oncology service will satisfy the given requirements for quality care. The existing reports from the American Association of Physicists in Medicine Task Groups 40 and 53 have provided highly detailed QA guidelines for conventional radiotherapy and treatment planning. However, advanced treatment processes recently developed with emerging high technology have introduced new QA requirements that have not been addressed previously in the conventional QA program. Therefore, it is necessary to expand the existing QA guidelines to also include new considerations. Image-guided adaptive radiation therapy (IGART) is a closed-loop treatment process that is designed to include the individual treatment information, such as patient-specific anatomic variation and delivered dose assessed during the therapy course in treatment evaluation and planning optimization. Clinical implementation of IGART requires high levels of automation in image acquisition, registration, segmentation, treatment dose construction, and adaptive planning optimization, which brings new challenges to the conventional QA program. In this article, clinical QA procedures for IGART are outlined. The discussion focuses on the dynamic or four-dimensional aspects of the IGART process, avoiding overlap with conventional QA guidelines.

Yan Di [Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, MI (United States)], E-mail: dyan@beaumont.edu

2008-05-01T23:59:59.000Z

166

A Population-Based Study of the Fractionation of Postlumpectomy Breast Radiation Therapy  

SciTech Connect

Purpose: The optimal fractionation schedule of post lumpectomy radiation therapy remains controversial. The objective of this study was to describe the fractionation of post-lumpectomy radiation therapy (RT) in Ontario, before and after the seminal Ontario Clinical Oncology Group (OCOG) trial, which showed the equivalence of 16- and 25-fraction schedules. Methods and Materials: This was a retrospective cohort study conducted by linking electronic treatment records to a population-based cancer registry. The study population included all patients who underwent lumpectomy for invasive breast cancer in Ontario, Canada, between 1984 and 2008. Results: Over the study period, 41,747 breast cancer patients received post lumpectomy radiation therapy to the breast only. Both 16- and 25-fraction schedules were commonly used throughout the study period. In the early 1980s, shorter fractionation schedules were used in >80% of cases. Between 1985 and 1995, the proportion of patients treated with shorter fractionation decreased to 48%. After completion of the OCOG trial, shorter fractionation schemes were once again widely adopted across Ontario, and are currently used in about 71% of cases; however, large intercenter variations in fractionation persisted. Conclusions: The use of shorter schedules of post lumpectomy RT in Ontario increased after completion of the OCOG trial, but the trial had a less normative effect on practice than expected.

Ashworth, Allison [Division of Cancer Care and Epidemiology, Queen's University Cancer Research Institute, Kingston, Ontario (Canada) [Division of Cancer Care and Epidemiology, Queen's University Cancer Research Institute, Kingston, Ontario (Canada); Cancer Center of Southeastern Ontario, Kingston, Ontario (Canada); Kong, Weidong [Division of Cancer Care and Epidemiology, Queen's University Cancer Research Institute, Kingston, Ontario (Canada)] [Division of Cancer Care and Epidemiology, Queen's University Cancer Research Institute, Kingston, Ontario (Canada); Whelan, Timothy [Juravinski Cancer Center, Hamilton, Ontario (Canada)] [Juravinski Cancer Center, Hamilton, Ontario (Canada); Mackillop, William J., E-mail: william.mackillop@krcc.on.ca [Division of Cancer Care and Epidemiology, Queen's University Cancer Research Institute, Kingston, Ontario (Canada)

2013-05-01T23:59:59.000Z

167

Radiation-Induced Bystander Effects and Relevance to Human Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation-Induced Bystander Effects and Relevance to Human Radiation Radiation-Induced Bystander Effects and Relevance to Human Radiation Exposures Review of phenomenon appears in Radiation Research Pamela Sykes and Benjamin Blyth One concern of radiobiologists is the effect radiation exposure might have on nearby unirradiated cells. For example, when only a small fraction of cells are directly hit by radiation energy, are the surrounding unirradiated cells also at an increased risk of cancer? The term "radiation-induced bystander effect" is used to describe radiation-induced biological changes that occur in unirradiated cells within an irradiated cell population. Radiation-induced bystander effects have become established in the vernacular and are considered as an authentic radiation response. However, there is still no consensus on a precise definition of the term, which

168

RADIATIVE TRANSFER IN ULTRARELATIVISTIC OUTFLOWS  

SciTech Connect

Analytical and numerical solutions are obtained for the equation of radiative transfer in ultrarelativistic opaque jets. The solution describes the initial trapping of radiation, its adiabatic cooling, and the transition to transparency. Two opposite regimes are examined. (1) Matter-dominated outflow. Surprisingly, radiation develops enormous anisotropy in the fluid frame before decoupling from the fluid. The radiation is strongly polarized. (2) Radiation-dominated outflow. The transfer occurs as if radiation propagated in vacuum, preserving the angular distribution and the blackbody shape of the spectrum. The escaping radiation has a blackbody spectrum if (and only if) the outflow energy is dominated by radiation up to the photospheric radius.

Beloborodov, Andrei M., E-mail: amb@phys.columbia.edu [Physics Department and Columbia Astrophysics Laboratory, Columbia University, 538 West 120th Street New York, NY 10027 (United States)

2011-08-20T23:59:59.000Z

169

Florida Radiation Protection Act (Florida)  

Energy.gov (U.S. Department of Energy (DOE))

The Department of Public Health is responsible for administering a statewide radiation protection program. The program is designed to permit development and utilization of sources of radiation for...

170

Radiation prevents much cancer  

Science Journals Connector (OSTI)

Evidence reviewed here supports the concept that chronic exposure to ionising radiation can dramatically decrease cancer incidence and mortality. This evidence includes an inverse relationship between radiation levels and cancer induction and/or mortality in: over 200 million people in the USA; 200 million people in India; 10,000 residents of Taipei who live in cobalt-60 contaminated homes; high radiation areas of Ramsar, Iran; 12 million person-years of exposed and carefully selected control nuclear workers; almost 300,000 homes with radon in the USA; non-smokers in high radon areas of Saxony, Germany.

T.D. Luckey

2007-01-01T23:59:59.000Z

171

Biophysics and synchrotron radiation  

SciTech Connect

This book, contains contributions to the conference on Biophysics and Synchrotron Radiation held in July 1986 at Frascati. It is devoted to advances in the resolution of biological molecule structure obtainable through synchroton radiation studies. The use of synchroton radiation has firmly established x-ray spectroscopy of biological molecules. More detailed knowledge on the local structure of active sites of metalloproteins, as well as a number of studies on the interaction of metal ions with other important biological macromolecular systems are presented. This new method for protein structure analysis is a major improvement for the rapidly expanding field of protein engineering.

Bianconi, A.; Castellano, C.C.

1987-01-01T23:59:59.000Z

172

Miniaturized radiation chirper  

DOE Patents (OSTI)

The disclosure relates to a miniaturized radiation chirper for use with a small battery supplying on the order of 5 volts. A poor quality CdTe crystal which is not necessarily suitable for high resolution gamma ray spectroscopy is incorporated with appropriate electronics so that the chirper emits an audible noise at a rate that is proportional to radiation exposure level. The chirper is intended to serve as a personnel radiation warning device that utilizes new and novel electronics with a novel detector, a CdTe crystal. The resultant device is much smaller and has much longer battery life than existing chirpers.

Umbarger, C. John (Los Alamos, NM); Wolf, Michael A. (Los Alamos, NM)

1980-01-01T23:59:59.000Z

173

Composition for radiation shielding  

DOE Patents (OSTI)

A composition for use as a radiation shield. The shield has a depleted urum core for absorbing gamma rays and a bismuth coating for preventing chemical corrosion and absorbing gamma rays. Alternatively, a sheet of gadolinium may be positioned between the uranium core and the bismuth coating for absorbing neutrons. The composition is preferably in the form of a container for storing materials that emit radiation such as gamma rays and neutrons. The container is preferably formed by casting bismuth around a pre-formed uranium container having a gadolinium sheeting, and allowing the bismuth to cool. The resulting container is a structurally sound, corrosion-resistant, radiation-absorbing container.

Kronberg, James W. (Aiken, SC)

1994-01-01T23:59:59.000Z

174

The Intense Radiation Gas  

E-Print Network (OSTI)

We present a new dispersion relation for photons that are nonlinearly interacting with a radiation gas of arbitrary intensity due to photon-photon scattering. It is found that the photon phase velocity decreases with increasing radiation intensity, it and attains a minimum value in the limit of super-intense fields. By using Hamilton's ray equations, a self-consistent kinetic theory for interacting photons is formulated. The interaction between an electromagnetic pulse and the radiation gas is shown to produce pulse self-compression and nonlinear saturation. Implications of our new results are discussed.

M. Marklund; P. K. Shukla; B. Eliasson

2005-03-08T23:59:59.000Z

175

ARM - Measurement - Backscattered radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

govMeasurementsBackscattered radiation govMeasurementsBackscattered radiation ARM Data Discovery Browse Data Comments? We would love to hear from you! Send us a note below or call us at 1-888-ARM-DATA. Send Measurement : Backscattered radiation The scattering of radiant energy into the hemisphere of space bounded by a plane normal to the direction of the incident radiation and lying on the same side as the incident ray. Categories Aerosols, Cloud Properties Instruments The above measurement is considered scientifically relevant for the following instruments. Refer to the datastream (netcdf) file headers of each instrument for a list of all available measurements, including those recorded for diagnostic or quality assurance purposes. ARM Instruments AOS : Aerosol Observing System IAP : In-situ Aerosol Profiles (Cessna Aerosol Flights)

176

Low Dose Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Ancient Salt Beds Ancient Salt Beds Repository Science Renewable Energy The WIPP Underground may be ideal to study effects of Very Low Dose Rates on Biological Systems Low Background Radiation Experiment We're all bathing in it. It's in the food we eat, the water we drink, the soil we tread and even the air we breathe. It's background radiation, it's everywhere and we can't get away from it. But what would happen if you somehow "pulled the plug" on natural background radiation? Would organisms suffer or thrive if they grew up without their constant exposure to background radiation? That's what a consortium of scientists conducting an experiment at the Waste Isolation Pilot Plant aim to find out. Despite being an underground repository for transuranic radioactive waste,

177

Radiation from accelerated branes  

Science Journals Connector (OSTI)

The radiation emitted by accelerated fundamental strings and D-branes is studied within the linear approximation to the supergravity limit of string theory. We show that scalar, gauge field and gravitational radiation is generically emitted by such branes. In the case where an external scalar field accelerates the branes, we derive a Larmor-type formula for the emitted scalar radiation and study the angular distribution of the outgoing energy flux. The classical radii of the branes are calculated by means of the corresponding Thompson scattering cross sections. Within the linear approximation, the interaction of the external scalar field with the velocity fields of the branes gives a contribution to the observed gauge field and gravitational radiation.

Mohab Abou-Zeid and Miguel S. Costa

2000-04-26T23:59:59.000Z

178

Radiation Induced Mammary Cancer  

Science Journals Connector (OSTI)

......Induced Mammary Cancer R.L. Ullrich * R.J. Preston # * Department of Radiation Therapy, University of Texas Medical Branch, Galveston, TX 77550 # Biology Division Oak Ridge National Laboratory Oak Ridge, TN 37831, U.S.A Over the last......

R.L. Ullrich; R.J. Preston

1991-12-01T23:59:59.000Z

179

Ionizing radiation detector  

DOE Patents (OSTI)

An ionizing radiation detector is provided which is based on the principle of analog electronic integration of radiation sensor currents in the sub-pico to nano ampere range between fixed voltage switching thresholds with automatic voltage reversal each time the appropriate threshold is reached. The thresholds are provided by a first NAND gate Schmitt trigger which is coupled with a second NAND gate Schmitt trigger operating in an alternate switching state from the first gate to turn either a visible or audible indicating device on and off in response to the gate switching rate which is indicative of the level of radiation being sensed. The detector can be configured as a small, personal radiation dosimeter which is simple to operate and responsive over a dynamic range of at least 0.01 to 1000 R/hr.

Thacker, Louis H. (Knoxville, TN)

1990-01-01T23:59:59.000Z

180

Flexible Composite Radiation Detector  

NLE Websites -- All DOE Office Websites (Extended Search)

Flexible Composite Radiation Detector Flexible Composite Radiation Detector Flexible Composite Radiation Detector A flexible composite scintillator was prepared by mixing fast, bright, dense rare-earth doped powdered oxyorthosilicate (such as LSO:Ce, LSO:Sm, and GSO:Ce) scintillator with a polymer binder. Available for thumbnail of Feynman Center (505) 665-9090 Email Flexible Composite Radiation Detector A flexible composite scintillator was prepared by mixing fast, bright, dense rare-earth doped powdered oxyorthosilicate (such as LSO:Ce, LSO:Sm, and GSO:Ce) scintillator with a polymer binder. The binder is transparent to the scintillator emission. The composite is seamless and can be made large and in a wide variety of shapes. Importantly, the composite can be tailored to emit light in a spectral region that matches the optimum

Note: This page contains sample records for the topic "radiation oncology feinberg" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


181

Radiation Safety Training Basic Radiation Safety Training for  

E-Print Network (OSTI)

Radiation Safety Training Basic Radiation Safety Training for Sealed Source Users for Physics 461 & 462 Modern Physics Laboratory Spring 2007 #12;Radiation Safety Department, University of Tennessee Purpose: To provide basic radiation safety training to the users of sealed sources located

Dai, Pengcheng

182

Radiation Safety Training Basic Radiation Safety Training for  

E-Print Network (OSTI)

Radiation Safety Training Basic Radiation Safety Training for X-ray Users for Physics 461 & 462 Modern Physics Laboratory Spring 2007 #12;#12;Radiation Safety Department, University of Tennessee Protocol Title: Basic Radiation Safety Training for X-ray Users Drafted By: Chris Millsaps, RSS Reviewers

Dai, Pengcheng

183

Radiative Muon Capture  

Science Journals Connector (OSTI)

The theory of radiative muon capture is developed. The discussion includes both parity conserving and nonconserving effects. The Gell-Mann weak magnetic term and the induced pseudoscalar are included, along with comparable relativistic effects in the nucleons. The theory is applied to light nuclei and especially to the radiative Godfrey reaction ?-+C126??+?+B125. An experiment to detect the induced pseudoscalar directly is proposed.

Jeremy Bernstein

1959-08-01T23:59:59.000Z

184

Low Dose Radiation Program: Links - Agencies with Radiation Regulatory  

NLE Websites -- All DOE Office Websites (Extended Search)

Agencies with Radiation Regulatory Concerns and Involvement Agencies with Radiation Regulatory Concerns and Involvement Biological Effects of Low Level Exposures (BELLE) Canadian Nuclear Safety Commission Center for Risk Excellence Health Protection Agency The Health Risks of Extraterrestrial Environments International Commission on Radiation Units and Measurements, Inc. International Commission on Radiological Protection (ICRP) International Radiation Protection Association (IRPA) NASA Space Radiation Program National Academy of Sciences (NAS) Nuclear and Radiation Studies Board National Aeronautics and Space Administration (NASA) NASA OBRR Task Book Publication National Council on Radiation Protection (NCRP) National Institute of Environmental Health Sciences (NIEHS) National Toxicology Program (NTP) Occupational Safety and Health Administration (OSHA)

185

Dosimetric effects of weight loss or gain during volumetric modulated arc therapy and intensity-modulated radiation therapy for prostate cancer  

SciTech Connect

Weight loss or gain during the course of radiation therapy for prostate cancer can alter the planned dose to the target volumes and critical organs. Typically, source-to-surface distance (SSD) measurements are documented by therapists on a weekly basis to ensure that patients' exterior surface and isocenter-to-skin surface distances remain stable. The radiation oncology team then determines whether the patient has undergone a physical change sufficient to require a new treatment plan. The effect of weight change (SSD increase or decrease) on intensity-modulated radiation therapy (IMRT) or volumetric modulated arc therapy (VMAT) dosimetry is not well known, and it is unclear when rescanning or replanning is needed. The purpose of this study was to determine the effects of weight change (SSD increase or decrease) on IMRT or VMAT dose delivery in patients with prostate cancer and to determine the SSD change threshold for replanning. Whether IMRT or VMAT provides better dose stability under weight change conditions was also determined. We generated clinical IMRT and VMAT prostate and seminal vesicle treatment plans for varying SSDs for 10 randomly selected patients with prostate cancer. The differences due to SSD change were quantified by a specific dose change for a specified volume of interest. The target mean dose, decreased or increased by 2.9% per 1-cm SSD decrease or increase in IMRT and by 3.6% in VMAT. If the SSD deviation is more than 1 cm, the radiation oncology team should determine whether to continue treatment without modifications, to adjust monitor units, or to resimulate and replan.

Pair, Matthew L. [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX (United States); Du, Weiliang [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, TX (United States); Rojas, Hector D.; Kanke, James E.; McGuire, Sean E.; Lee, Andrew K.; Kuban, Deborah A. [Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX (United States); Kudchadker, Rajat J., E-mail: rkudchad@mdanderson.org [Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, TX (United States)

2013-10-01T23:59:59.000Z

186

Radiation and viral DNA  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation and viral DNA Radiation and viral DNA Name: Loretta L Lamb Age: N/A Location: N/A Country: N/A Date: N/A Question: Can viral DNA be changed through exposure to radiation? If so, what type of radiation will do this? Can these irradiated viruses cause changes in the genome of any human cells they may infect? Can these (or any) viruses actually cause cancer, or do they merely act as triggering devices for cancer? Replies: In theory, any nucleic acid (viral or otherwise) can be changed by exposure to many kinds of radiation. Depending on the type of virus, these may then change the human cells that they infect. Although there are many different things that are being implicated in causing cancers, it looks like a fairly common model involves the sequential "knockout" of several human genes. Viruses may be one cause of such gene changes, radiation and other environmental causes may also contribute. Some of these changes may be inherited through families, so it becomes more likely that the environmental factors may happen to "hit" the right places in cells to cause cancers in these families. If you ask something more specific, perhaps I can focus my response a bit more

187

Radiative muon capture  

Science Journals Connector (OSTI)

It is shown by relating the transition amplitude of radiative muon capture to that of radiative pion capture, that the transition amplitude of radiative muon capture proposed recently by Hwang and Primakoff differs from the others mainly by Low's counter terms. Despite the fact that the "original" transition amplitude does not violate seriously the conservation of the hadronic electromagnetic current, Low's counter terms, as introduced via Low's prescription to secure the presence of small conservation-of-hadronic-electromagnetic-current-breaking terms, are confirmed to be of numerical importance. Further, it is found in the "elementary-particle" treatment of radiative muon capture that the uncertainty arising from the nuclear structure can be reduced to become negligible. Therefore, an exclusive radiative muon capture experiment can in principle differentiate the Hwang-Primakoff theory from the others and yet provide a comprehensive test of partial conservation of axial-vector current.RADIOACTIVITY Theories of radiative muon capture, linearity hypothesis versus Low's prescription; nuclear structure and PCAC.

W -Y. P. Hwang

1980-07-01T23:59:59.000Z

188

Hypofractionated Whole-Breast Radiation Therapy: Does Breast Size Matter?  

SciTech Connect

Purpose: To evaluate the effects of breast size on dose-volume histogram parameters and clinical toxicity in whole-breast hypofractionated radiation therapy using intensity modulated radiation therapy (IMRT). Materials and Methods: In this retrospective study, all patients undergoing breast-conserving therapy between 2005 and 2009 were screened, and qualifying consecutive patients were included in 1 of 2 cohorts: large-breasted patients (chest wall separation >25 cm or planning target volume [PTV] >1500 cm{sub 3}) (n=97) and small-breasted patients (chest wall separation <25 cm and PTV <1500 cm{sub 3}) (n=32). All patients were treated prone or supine with hypofractionated IMRT to the whole breast (42.4 Gy in 16 fractions) followed by a boost dose (9.6 Gy in 4 fractions). Dosimetric and clinical toxicity data were collected and analyzed using the R statistical package (version 2.12). Results: The mean PTV V95 (percentage of volume receiving >= 95% of prescribed dose) was 90.18% and the mean V105 percentage of volume receiving >= 105% of prescribed dose was 3.55% with no dose greater than 107%. PTV dose was independent of breast size, whereas heart dose and maximum point dose to skin correlated with increasing breast size. Lung dose was markedly decreased in prone compared with supine treatments. Radiation Therapy Oncology Group grade 0, 1, and 2 skin toxicities were noted acutely in 6%, 69%, and 25% of patients, respectively, and at later follow-up (>3 months) in 43%, 57%, and 0% of patients, respectively. Large breast size contributed to increased acute grade 2 toxicity (28% vs 12%, P=.008). Conclusions: Adequate PTV coverage with acceptable hot spots and excellent sparing of organs at risk was achieved by use of IMRT regardless of treatment position and breast size. Although increasing breast size leads to increased heart dose and maximum skin dose, heart dose remained within our institutional constraints and the incidence of overall skin toxicity was comparable to that reported in the literature. Taken together, these data suggest that hypofractionated radiation therapy using IMRT is a viable and appropriate therapeutic modality in large-breasted patients.

Hannan, Raquibul, E-mail: Raquibul.Hannan@gmail.com [Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas (United States)] [Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas (United States); Thompson, Reid F.; Chen Yu; Bernstein, Karen; Kabarriti, Rafi; Skinner, William [Department of Radiation Oncology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York (United States)] [Department of Radiation Oncology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York (United States); Chen, Chin C. [Department of Radiation Oncology, Columbia University Medical Center, New York, New York (United States)] [Department of Radiation Oncology, Columbia University Medical Center, New York, New York (United States); Landau, Evan; Miller, Ekeni; Spierer, Marnee; Hong, Linda; Kalnicki, Shalom [Department of Radiation Oncology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York (United States)] [Department of Radiation Oncology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York (United States)

2012-11-15T23:59:59.000Z

189

REPORT NO. 8 radiation hazards  

E-Print Network (OSTI)

REPORT NO. 8 REVISED guidance for the control of radiation hazards in uranium mining SEPTEMBER 1967 OF RADIATION HAZARDS IN URANIUM MINING SEPTEMBER 1967 Staff Report of the FEDERAL RADIATION COUNCIL #12;FEDERAL...... .... .._ _.... Section I. Introduction. . . Section II. The Radiation Environment AssociatedWith Uranium Mining. Section

190

Appendix G: Radiation HYDROGEN ATOM  

E-Print Network (OSTI)

. People are exposed to naturally occurring radiation constantly. For example, cosmic radiation; radon effects on the environment and biological systems. Radiation comes from natural and human-made sourcesAppendix G: Radiation #12;#12;P P P E E E N NN HYDROGEN ATOM DEUTERIUM ATOM TRITIUM ATOM HYDROGEN

Pennycook, Steve

191

Appendix A: Radiation HYDROGEN ATOM  

E-Print Network (OSTI)

. People are exposed to naturally occurring radiation constantly. For example, cosmic radiation; radon effects on the environment and biological systems. Radiation comes from natural and human-made sourcesAppendix A: Radiation #12;P P P E E E N NN HYDROGEN ATOM DEUTERIUM ATOM TRITIUM ATOM HYDROGEN

Pennycook, Steve

192

Proteasome Structures Affected by Ionizing Radiation  

Science Journals Connector (OSTI)

...Effect of ionizing radiation on 26S but...radiation doses, and immediately...the dose range 1 to 20 Gy...ionizing radiation induced a...38), ionizing radiation (39...over a wide range of radiation doses and further...

Milena Pervan; Keisuke S. Iwamoto; and William H. McBride

2005-07-01T23:59:59.000Z

193

Radiation delivery system and method  

DOE Patents (OSTI)

A radiation delivery system and method are described. The system includes a treatment configuration such as a stent, balloon catheter, wire, ribbon, or the like, a portion of which is covered with a gold layer. Chemisorbed to the gold layer is a radiation-emitting self-assembled monolayer or a radiation-emitting polymer. The radiation delivery system is compatible with medical catheter-based technologies to provide a therapeutic dose of radiation to a lesion following an angioplasty procedure.

Sorensen, Scott A. (Overland Park, KS); Robison, Thomas W. (Los Alamos, NM); Taylor, Craig M. V. (Jemez Springs, NM)

2002-01-01T23:59:59.000Z

194

Nanotechnology and individualized oncology  

Science Journals Connector (OSTI)

...Targeting intracellular VEGF using nanotechnology for subcellular delivery of bevacizumab...neutralizing the intracellular VEGF using nanotechnology-based delivery of bevacizumab...intracellular delivery of Avastin by using nanotechnology. Pancreatic cancer (PanCa) is highly...

Mauro Ferrari

2010-10-01T23:59:59.000Z

195

Reducing Radiation Damage  

SciTech Connect

This talk describes the use of a modified treatment sequence, i.e., radiation dose, geometry, dwell time, etc., to mitigate some of the deleterious effects of cancer radiotherapy by utilizing natural cell repair processes. If bad side effects can be reduced, a more aggressive therapy can be put into place. Cells contain many mechanisms that repair damage of various types. If the damage can not be repaired, cells will undergo apoptosis (cell death). Data will be reviewed that support the fact that a small dose of radiation will activate damage repair genes within a cell. Once the mechanisms are fully active, they will efficiently repair the severe damage from a much larger radiation dose. The data ranges from experiments on specific cell cultures using microarray (gene chip) techniques to experiments on complete organisms. The suggested effect and treatment is consistent with the assumption that all radiation is harmful, no matter how small the dose. Nevertheless, the harm can be reduced. These mechanisms need to be further studied and characterized. In particular, their time dependence needs to be understood before the proposed treatment can be optimized. Under certain situations it is also possible that the deleterious effects of chemotherapy can be mitigated and the damage to radiation workers can be reduced.

Blankenbecler, Richard

2006-06-05T23:59:59.000Z

196

Low Dose Radiation Program: Links - Organizations Conducting Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Conducting Low Dose Radiation Research Conducting Low Dose Radiation Research DOE Low Dose Radiation Research Program DoReMi Integrating Low Dose Research High Level Expert Group (HLEG) on European Low Dose Risk Research Multidisciplinary European Low Dose Initiative (MELODI) RISC-RAD Radiosensitivity of Individuals and Susceptibility to Cancer induced by Ionizing Radiation United States Transuranium & Uranium Registries Organizations Conducting other Radiation Research Argonne National Laboratory (ANL) Armed Forces Radiology Research Institute (AFRRI) Atmospheric Radiation Measurement (ARM) Program Brookhaven National Laboratory (BNL) Center for Devices and Radiological Health (CDRH) Central Research Institute of Electric Power Industry (CRIEPI) Colorado State University Columbia University

197

Semiconductor radiation detector  

DOE Patents (OSTI)

A semiconductor detector for ionizing electromagnetic radiation, neutrons, and energetic charged particles. The detecting element is comprised of a compound having the composition I-III-VI.sub.2 or II-IV-V.sub.2 where the "I" component is from column 1A or 1B of the periodic table, the "II" component is from column 2B, the "III" component is from column 3A, the "IV" component is from column 4A, the "V" component is from column 5A, and the "VI" component is from column 6A. The detecting element detects ionizing radiation by generating a signal proportional to the energy deposited in the element, and detects neutrons by virtue of the ionizing radiation emitted by one or more of the constituent materials subsequent to capture. The detector may contain more than one neutron-sensitive component.

Bell, Zane W. (Oak Ridge, TN); Burger, Arnold (Knoxville, TN)

2010-03-30T23:59:59.000Z

198

Radiation Minimum Temperatures  

Science Journals Connector (OSTI)

Frost resulting from cooling of vegetation by nocturnal radiation is a serious agricultural problem. Because of the number of variables involved attacks on this problem from a purely theoretical point of view have met with only moderate success. It seems logical to suppose that an instrument might be devised which would speed up the natural radiation processes and enable an observer to obtain in a few hours a measure of the cooling which occurs naturally over a period of 12 to 14 hr. Such an instrument could serve as a frost warning device. This paper describes the construction of a radiation device and presents experimental evidence to show that it can be used as a predictor of freezing temperatures at vegetation level.

Francis K. Davis Jr.

1957-01-01T23:59:59.000Z

199

Audible radiation monitor  

SciTech Connect

This invention consists of a method and apparatus for monitoring ionizing radiation comprising radiation detectors in electrical connection with an isotopic analyzer and a device for producing chords to which each isotope is mapped so that the device produces a unique chord for each isotope. Preferably the chords are pleasing to the ear, except for chords representing unexpected isotopes, and are louder or softer depending on the level of radioactivity produced by each isotope, and musical instrument voices may be simulated in producing the chords as an aid to distinguishing similar-sounding chords. Because of the representation by chords, information regarding the level and composition of the radiation in an area can be conveyed to workers in that area more effectively and yet without distracting them.

Odell, D.M.C.

1992-12-31T23:59:59.000Z

200

Composition for radiation shielding  

DOE Patents (OSTI)

A composition for use as a radiation shield is disclosed. The shield has a depleted uranium core for absorbing gamma rays and a bismuth coating for preventing chemical corrosion and absorbing gamma rays. Alternatively, a sheet of gadolinium may be positioned between the uranium core and the bismuth coating for absorbing neutrons. The composition is preferably in the form of a container for storing materials that emit radiation such as gamma rays and neutrons. The container is preferably formed by casting bismuth around a pre-formed uranium container having a gadolinium sheeting, and allowing the bismuth to cool. The resulting container is a structurally sound, corrosion-resistant, radiation-absorbing container. 2 figs.

Kronberg, J.W.

1994-08-02T23:59:59.000Z

Note: This page contains sample records for the topic "radiation oncology feinberg" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


201

Tunable terahertz radiation source  

SciTech Connect

Terahertz radiation source and method of producing terahertz radiation, said source comprising a junction stack, said junction stack comprising a crystalline material comprising a plurality of self-synchronized intrinsic Josephson junctions; an electrically conductive material in contact with two opposing sides of said crystalline material; and a substrate layer disposed upon at least a portion of both the crystalline material and the electrically-conductive material, wherein the crystalline material has a c-axis which is parallel to the substrate layer, and wherein the source emits at least 1 mW of power.

Boulaevskii, Lev; Feldmann, David M; Jia, Quanxi; Koshelev, Alexei; Moody, Nathan A

2014-01-21T23:59:59.000Z

202

Clinical Outcomes of Intensity-Modulated Pelvic Radiation Therapy for Carcinoma of the Cervix  

SciTech Connect

Purpose: To evaluate disease outcomes and toxicity in cervical cancer patients treated with pelvic intensity-modulated radiation therapy (IMRT). Methods and Materials: We included all patients with Stage I-IVA cervical carcinoma treated with IMRT at three different institutions from 2000-2007. Patients treated with extended field or conventional techniques were excluded. Intensity-modulated radiation therapy plans were designed to deliver 45 Gy in 1.8-Gy daily fractions to the planning target volume while minimizing dose to the bowel, bladder, and rectum. Toxicity was graded according to the Radiation Therapy Oncology Group system. Overall survival and disease-free survival were estimated by use of the Kaplan-Meier method. Pelvic failure, distant failure, and late toxicity were estimated by use of cumulative incidence functions. Results: The study included 111 patients. Of these, 22 were treated with postoperative IMRT, 8 with IMRT followed by intracavitary brachytherapy and adjuvant hysterectomy, and 81 with IMRT followed by planned intracavitary brachytherapy. Of the patients, 63 had Stage I-IIA disease and 48 had Stage IIB-IVA disease. The median follow-up time was 27 months. The 3-year overall survival rate and the disease-free survival rate were 78% (95% confidence interval [CI], 68-88%) and 69% (95% CI, 59-81%), respectively. The 3-year pelvic failure rate and the distant failure rate were 14% (95% CI, 6-22%) and 17% (95% CI, 8-25%), respectively. Estimates of acute and late Grade 3 toxicity or higher were 2% (95% CI, 0-7%) and 7% (95% CI, 2-13%), respectively. Conclusions: Intensity-modulated radiation therapy is associated with low toxicity and favorable outcomes, supporting its safety and efficacy for cervical cancer. Prospective clinical trials are needed to evaluate the comparative efficacy of IMRT vs. conventional techniques.

Hasselle, Michael D. [Departments of Radiation and Cellular Oncology, University of Chicago, Chicago, IL (United States); Rose, Brent S. [Department of Radiation Oncology, Center for Advanced Radiotherapy Technologies, University of California, San Diego, La Jolla, CA (United States); Kochanski, Joel D. [Departments of Radiation and Cellular Oncology, University of Chicago, Chicago, IL (United States); Nath, Sameer K. [Department of Radiation Oncology, Center for Advanced Radiotherapy Technologies, University of California, San Diego, La Jolla, CA (United States); Bafana, Rounak [Wayne State University School of Medicine, Detroit, MI (United States); Yashar, Catheryn M. [Department of Radiation Oncology, Center for Advanced Radiotherapy Technologies, University of California, San Diego, La Jolla, CA (United States); Hasan, Yasmin [Departments of Radiation and Cellular Oncology, University of Chicago, Chicago, IL (United States); Roeske, John C. [Department of Radiation Oncology, Loyola University, Maywood, IL (United States); Mundt, Arno J. [Department of Radiation Oncology, Center for Advanced Radiotherapy Technologies, University of California, San Diego, La Jolla, CA (United States); Mell, Loren K., E-mail: lmell@ucsd.edu [Department of Radiation Oncology, Center for Advanced Radiotherapy Technologies, University of California, San Diego, La Jolla, CA (United States)

2011-08-01T23:59:59.000Z

203

RADIATION ALERT User Manual  

E-Print Network (OSTI)

not contaminate the Inspector by touching it to radioactive surfaces or materials. If contamination is suspected Environmental Area Monitoring 16 Checking for Surface Contamination 16 5 Maintenance 17 Calibration 17, and x-ray radiation. Its applications include: · Detecting and measuring surface contamination

Haller, Gary L.

204

Radiation Source Replacement Workshop  

SciTech Connect

This report summarizes a Radiation Source Replacement Workshop in Houston Texas on October 27-28, 2010, which provided a forum for industry and researchers to exchange information and to discuss the issues relating to replacement of AmBe, and potentially other isotope sources used in well logging.

Griffin, Jeffrey W.; Moran, Traci L.; Bond, Leonard J.

2010-12-01T23:59:59.000Z

205

Solar energy: Radiation nation  

Science Journals Connector (OSTI)

... Australia receives more solar radiation per square metre, on average, than any other continent. Although turning this ... to make use of its heat. We spoke to Australian proponents of two very different solar-thermal systems, both rather confusingly known as ...

Carina Dennis

2006-09-06T23:59:59.000Z

206

Psoriasis and ultraviolet radiation  

SciTech Connect

Prevention and detection screening programs as a public health service in curtailing the ever-increasing incidence of all forms of skin cancer are reviewed. The effect of solar and artificial ultraviolet radiation on the general population and persons with psoriasis is examined. 54 refs.

Farber, E.M.; Nall, L. (Psoriasis Research Institute, Palo Alto, CA (United States))

1993-09-01T23:59:59.000Z

207

Local microwave background radiation  

E-Print Network (OSTI)

An inquiry on a possible local origin for the Microwave Background Radiation is made. Thermal MBR photons are contained in a system called {\\it magnetic bottle} which is due to Earth magnetic field and solar wind particles, mostly electrons. Observational tests are anticipated.

Domingos Soares

2014-11-13T23:59:59.000Z

208

Infrared radiation: Herschel revisited  

Science Journals Connector (OSTI)

The year 2000 marks the 200th anniversary of Herschel’s discovery of infrared radiation. Using a car light in place of the Sun and a liquid crystal sheet instead of thermometers the experiment is an effective classroom demonstration of invisible light.

Erin E. Pursell; Richard Kozlowski

2000-01-01T23:59:59.000Z

209

Radiation detector spectrum simulator  

DOE Patents (OSTI)

A small battery operated nuclear spectrum simulator having a noise source nerates pulses with a Gaussian distribution of amplitudes. A switched dc bias circuit cooperating therewith generates several nominal amplitudes of such pulses and a spectral distribution of pulses that closely simulates the spectrum produced by a radiation source such as Americium 241.

Wolf, Michael A. (Los Alamos, NM); Crowell, John M. (Los Alamos, NM)

1987-01-01T23:59:59.000Z

210

Radiation detector spectrum simulator  

DOE Patents (OSTI)

A small battery operated nuclear spectrum simulator having a noise source generates pulses with a Gaussian distribution of amplitudes. A switched dc bias circuit cooperating therewith to generate several nominal amplitudes of such pulses and a spectral distribution of pulses that closely simulates the spectrum produced by a radiation source such as Americium 241.

Wolf, M.A.; Crowell, J.M.

1985-04-09T23:59:59.000Z

211

Assessing exposure to radiation  

SciTech Connect

Since the founding of Lawrence Livermore National Laboratory, we have been world leaders in evaluating the risks associated with radiation. Ultrasensitive tools allow us not only to measure radionuclides present in the body but also to reconstruct the radiation dose from past nuclear events and to project the levels of radiation that will still be present in the body for 50 years after the initial intake. A variety of laboratory procedures, including some developed here, give us detailed information on the effects of radiation at the cellular level. Even today, we are re-evaluating the neutron dose resulting from the bombing at Hiroshima. Our dose reconstruction and projection capabilities have also been applied to studies of Nagasaki, Chernobyl, the Mayak industrial complex in the former Soviet Union, the Nevada Test Site, Bikini Atoll, and other sites. We are evaluating the information being collected on individuals currently working with radioactive material at Livermore and elsewhere as well as previously collected data on workers that extends back to the Manhattan Project.

Walter, K.

1997-01-01T23:59:59.000Z

212

Brachial Plexopathy in Apical Non-Small Cell Lung Cancer Treated With Definitive Radiation: Dosimetric Analysis and Clinical Implications  

SciTech Connect

Purpose: Data are limited on the clinical significance of brachial plexopathy in patients with apical non-small cell lung cancers (NSCLC) treated with definitive radiation therapy. We report the rates of radiation-induced brachial plexopathy (RIBP) and tumor-related brachial plexopathy (TRBP) and associated dosimetric parameters in apical NSCLC patients. Methods and Materials: Charts of NSCLC patients with primary upper lobe or superiorly located nodal disease who received {>=}50 Gy of definitive conventionally fractionated radiation or chemoradiation were retrospectively reviewed for evidence of brachial plexopathy and categorized as RIBP, TRBP, or trauma-related. Dosimetric data were gathered on ipsilateral brachial plexuses (IBP) contoured according to Radiation Therapy Oncology Group atlas guidelines. Results: Eighty patients were identified with a median follow-up and survival time of 17.2 and 17.7 months, respectively. The median prescribed dose was 66.6 Gy (range, 50.4-84.0), and 71% of patients received concurrent chemotherapy. RIBP occurred in 5 patients with an estimated 3-year rate of 12% when accounting for competing risk of death. Seven patients developed TRBP (estimated 3-year rate of 13%), comprising 24% of patients who developed locoregional failures. Grade 3 brachial plexopathy was more common in patients who experienced TRBP than RIBP (57% vs 20%). No patient who received {<=}78 Gy to the IBP developed RIBP. On multivariable competing risk analysis, IBP V76 receiving {>=}1 cc, and primary tumor failure had the highest hazard ratios for developing RIBP and TRBP, respectively. Conclusions: RIBP is a relatively uncommon complication in patients with apical NSCLC tumors receiving definitive doses of radiation, while patients who develop primary tumor failures are at high risk for developing morbid TRBP. These findings suggest that the importance of primary tumor control with adequate doses of radiation outweigh the risk of RIBP in this population of patients.

Eblan, Michael J.; Corradetti, Michael N.; Lukens, J. Nicholas; Xanthopoulos, Eric [Department of Radiation Oncology, Abramson Cancer Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania (United States)] [Department of Radiation Oncology, Abramson Cancer Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania (United States); Mitra, Nandita [Department of Biostatistics and Epidemiology, Abramson Cancer Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania (United States)] [Department of Biostatistics and Epidemiology, Abramson Cancer Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania (United States); Christodouleas, John P.; Grover, Surbhi; Fernandes, Annemarie T. [Department of Radiation Oncology, Abramson Cancer Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania (United States)] [Department of Radiation Oncology, Abramson Cancer Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania (United States); Langer, Corey J.; Evans, Tracey L.; Stevenson, James [Department of Medical Oncology, Abramson Cancer Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania (United States)] [Department of Medical Oncology, Abramson Cancer Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania (United States); Rengan, Ramesh [Department of Radiation Oncology, Abramson Cancer Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania (United States)] [Department of Radiation Oncology, Abramson Cancer Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania (United States); Apisarnthanarax, Smith, E-mail: apisarns@uphs.upenn.edu [Department of Radiation Oncology, Abramson Cancer Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania (United States)] [Department of Radiation Oncology, Abramson Cancer Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania (United States)

2013-01-01T23:59:59.000Z

213

External audit of clinical practice and medical decision making in a new Asian oncology center: Results and implications for both developing and developed nations  

SciTech Connect

Purpose: The external audit of oncologist clinical practice is increasingly important because of the incorporation of audits into national maintenance of certification (MOC) programs. However, there are few reports of external audits of oncology practice or decision making. Our institution (The Cancer Institute, Singapore) was asked to externally audit an oncology department in a developing Asian nation, providing a unique opportunity to explore the feasibility of such a process. Methods and Materials: We audited 100 randomly selected patients simulated for radiotherapy in 2003, using a previously reported audit instrument assessing clinical documentation/quality assurance and medical decision making. Results: Clinical documentation/quality assurance, decision making, and overall performance criteria were adequate 74.4%, 88.3%, and 80.2% of the time, respectively. Overall 52.0% of cases received suboptimal management. Multivariate analysis revealed palliative intent was associated with improved documentation/clinical quality assurance (p = 0.07), decision making (p 0.007), overall performance (p = 0.003), and optimal treatment rates (p 0.07); non-small-cell lung cancer or central nervous system primary sites were associated with better decision making (p = 0.001), overall performance (p = 0.03), and optimal treatment rates (p = 0.002). Conclusions: Despite the poor results, the external audit had several benefits. It identified learning needs for future targeting, and the auditor provided facilitating feedback to address systematic errors identified. Our experience was also helpful in refining our national revalidation audit instrument. The feasibility of the external audit supports the consideration of including audit in national MOC programs.

Shakespeare, Thomas P. [North Coast Cancer Institute, Coffs Harbour, Sydney, NSW (Australia) and Cancer Institute (Singapore)]. E-mail: ThomasShakespeare@gmail.com; Back, Michael F. [Cancer Institute (Singapore); Lu, Jiade J. [Cancer Institute (Singapore); Lee, Khai Mun [Cancer Institute (Singapore); Mukherjee, Rahul K. [Cancer Institute (Singapore)

2006-03-01T23:59:59.000Z

214

ACS WFC CCD Radiation Test: The Radiation Environment  

E-Print Network (OSTI)

of external surfaces by naturally occurring atomic oxygen. CCD detectors are particularly vulnerable to damage damage. A comprehensive discussion of the types of radiation damage known to occur in CCDs is beyond1 ACS WFC CCD Radiation Test: The Radiation Environment Michael R. Jones Space Telescope Science

Sirianni, Marco

215

Nanoscale Engineering Of Radiation Tolerant Silicon Carbide....  

NLE Websites -- All DOE Office Websites (Extended Search)

Engineering Of Radiation Tolerant Silicon Carbide. Nanoscale Engineering Of Radiation Tolerant Silicon Carbide. Abstract: Radiation tolerance is determined by how effectively the...

216

Annual DOE Occupational Radiation Exposure Reports | Department...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Annual DOE Occupational Radiation Exposure Reports Annual DOE Occupational Radiation Exposure Reports September 24, 2013 Annual DOE Occupational Radiation Exposure | 2012 Report...

217

Occupational Radiation Exposure | Department of Energy  

Energy Savers (EERE)

Radiation Exposure Welcome The Occupational Radiation Exposure Information page on this web page is intended to provide the latest available information on radiation exposure to...

218

Acceleration and Classical Electromagnetic Radiation  

E-Print Network (OSTI)

Classical radiation from an accelerated charge is reviewed along with the reciprocal topic of accelerated observers detecting radiation from a static charge. This review commemerates Bahram Mashhoon's 60th birthday.

E. N. Glass

2008-01-09T23:59:59.000Z

219

Mathematical Problems of Radiative Equilibrium  

Science Journals Connector (OSTI)

... in turn with the cases of purely absorbing and grey material in local radiative equilibrium (Schwarzschild-Milne model) and that of monochromatic radiative equilibrium with scattering but zero emissivity (Schuster ...

1935-01-12T23:59:59.000Z

220

Health Physicist (Radiation Protection Specialist)  

Energy.gov (U.S. Department of Energy (DOE))

A successful candidate in this position will serve as the Health Physicist (Radiation Protection Specialist) senior subject matter expert for health physics/radiation safety at the sites. You will...

Note: This page contains sample records for the topic "radiation oncology feinberg" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


221

Nuclear radiation electronic gear (continued)  

Science Journals Connector (OSTI)

Nuclear radiation electronic gear (continued) ... Examines nuclear instrumentation available from several major U.S. manufacturers. ... Nuclear / Radiochemistry ...

S. Z. Lewin

1961-01-01T23:59:59.000Z

222

DOE Radiation Records Contacts List  

Energy.gov (U.S. Department of Energy (DOE))

DOE radiation records contact list for individuals to obtain records of occupational exposure directly from a DOE site.

223

Gamma radiation field intensity meter  

DOE Patents (OSTI)

A gamma radiation intensity meter measures dose rate of a radiation field. The gamma radiation intensity meter includes a tritium battery emitting beta rays generating a current which is essentially constant. Dose rate is correlated to an amount of movement of an electroscope element charged by the tritium battery. Ionizing radiation decreases the voltage at the element and causes movement. A bleed resistor is coupled between the electroscope support element or electrode and the ionization chamber wall electrode. 4 figs.

Thacker, L.H.

1995-10-17T23:59:59.000Z

224

Gamma radiation field intensity meter  

DOE Patents (OSTI)

A gamma radiation intensity meter measures dose rate of a radiation field. The gamma radiation intensity meter includes a tritium battery emitting beta rays generating a current which is essentially constant. Dose rate is correlated to an amount of movement of an electroscope element charged by the tritium battery. Ionizing radiation decreases the voltage at the element and causes movement. A bleed resistor is coupled between the electroscope support element or electrode and the ionization chamber wall electrode. 4 figs.

Thacker, L.H.

1994-08-16T23:59:59.000Z

225

Gamma radiation field intensity meter  

DOE Patents (OSTI)

A gamma radiation intensity meter measures dose rate of a radiation field. The gamma radiation intensity meter includes a tritium battery emitting beta rays generating a current which is essentially constant. Dose rate is correlated to an amount of movement of an electroscope element charged by the tritium battery. Ionizing radiation decreases the voltage at the element and causes movement. A bleed resistor is coupled between the electroscope support element or electrode and the ionization chamber wall electrode.

Thacker, Louis H. (Knoxville, TN)

1995-01-01T23:59:59.000Z

226

Gamma radiation field intensity meter  

DOE Patents (OSTI)

A gamma radiation intensity meter measures dose rate of a radiation field. The gamma radiation intensity meter includes a tritium battery emitting beta rays generating a current which is essentially constant. Dose rate is correlated to an amount of movement of an electroscope element charged by the tritium battery. Ionizing radiation decreases the voltage at the element and causes movement. A bleed resistor is coupled between the electroscope support element or electrode and the ionization chamber wall electrode.

Thacker, Louis H. (Knoxville, TN)

1994-01-01T23:59:59.000Z

227

Radiation Preservation of Food, Commercialization Technology and Economics in Radiation Processing  

Science Journals Connector (OSTI)

Radiation Preservation of Food, Commercialization Technology and Economics in Radiation Processing ...

H. F. Kraybill; D. C. Brunton

1960-05-01T23:59:59.000Z

228

Environment/Health/Safety (EHS): Radiation Protection Group: Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Who To Call Who To Call Rad Training Dosimetry Telemetry Laser Safety Radiation Safety Committee Pub-3000 Ch. 21 Forms RPG Procedures RPG Internal Radiation Safety Committee Charter Purpose The Berkeley Lab Radiation Safety Committee (RSC) is appointed by, and reports to, the Laboratory Director and is responsible for advising LBNL Management on all matters related to occupational and environmental radiation safety. The Radiation Safety Committee reviews and recommends approval of radiation safety policies and guides the Environment, Health and Safety Division and radiation user divisions in carrying out these programs. The scope of its actions will generally be in issues of broad institutional concern and impact, or areas of potential high consequence either in terms of safety or institutional needs.

229

Terahertz radiation mixer  

DOE Patents (OSTI)

A terahertz radiation mixer comprises a heterodyned field-effect transistor (FET) having a high electron mobility heterostructure that provides a gatable two-dimensional electron gas in the channel region of the FET. The mixer can operate in either a broadband pinch-off mode or a narrowband resonant plasmon mode by changing a grating gate bias of the FET. The mixer can beat an RF signal frequency against a local oscillator frequency to generate an intermediate frequency difference signal in the microwave region. The mixer can have a low local oscillator power requirement and a large intermediate frequency bandwidth. The terahertz radiation mixer is particularly useful for terahertz applications requiring high resolution.

Wanke, Michael C. (Albuquerque, NM); Allen, S. James (Santa Barbara, CA); Lee, Mark (Albuquerque, NM)

2008-05-20T23:59:59.000Z

230

Time encoded radiation imaging  

DOE Patents (OSTI)

The various technologies presented herein relate to detecting nuclear material at a large stand-off distance. An imaging system is presented which can detect nuclear material by utilizing time encoded imaging relating to maximum and minimum radiation particle counts rates. The imaging system is integrated with a data acquisition system that can utilize variations in photon pulse shape to discriminate between neutron and gamma-ray interactions. Modulation in the detected neutron count rates as a function of the angular orientation of the detector due to attenuation of neighboring detectors is utilized to reconstruct the neutron source distribution over 360 degrees around the imaging system. Neutrons (e.g., fast neutrons) and/or gamma-rays are incident upon scintillation material in the imager, the photons generated by the scintillation material are converted to electrical energy from which the respective neutrons/gamma rays can be determined and, accordingly, a direction to, and the location of, a radiation source identified.

Marleau, Peter; Brubaker, Erik; Kiff, Scott

2014-10-21T23:59:59.000Z

231

Radiation Emergency Procedure Demonstrations  

NLE Websites -- All DOE Office Websites (Extended Search)

Managing Radiation Emergencies Managing Radiation Emergencies Procedure Demonstrations Procedure Demonstrations Note: RealPlayer is needed for listening to the narration that accompany these demonstrations. Real Player Dressing To Prevent the Spread of Radioactive Contamination This demonstration shows how your team can dress to prevent the spread of radioactive contamination. Click to begin presentation on dressing to prevent the spread of radioactive contamination. Preparing The Area This demonstration shows basic steps you can take to gather equipment and prepare a room to receive a patient who may be contaminated with radioactive material. Click to begin presentation on preparing a room to receive a radioactive contaminated patient. Removing Contaminated Clothing This demonstration shows the procedure for removing clothing from a patient who may be contaminated with radioactive material.

232

Semiconductor radiation detector  

DOE Patents (OSTI)

A semiconductor radiation detector is provided to detect x-ray and light photons. The entrance electrode is segmented by using variable doping concentrations. Further, the entrance electrode is physically segmented by inserting n+ regions between p+ regions. The p+ regions and the n+ regions are individually biased. The detector elements can be used in an array, and the p+ regions and the n+ regions can be biased by applying potential at a single point. The back side of the semiconductor radiation detector has an n+ anode for collecting created charges and a number of p+ cathodes. Biased n+ inserts can be placed between the p+ cathodes, and an internal resistor divider can be used to bias the n+ inserts as well as the p+ cathodes. A polysilicon spiral guard can be implemented surrounding the active area of the entrance electrode or surrounding an array of entrance electrodes.

Patt, Bradley E. (Sherman Oaks, CA); Iwanczyk, Jan S. (Los Angeles, CA); Tull, Carolyn R. (Orinda, CA); Vilkelis, Gintas (Westlake Village, CA)

2002-01-01T23:59:59.000Z

233

Aharonov-Bohm radiation  

SciTech Connect

A solenoid oscillating in vacuum will pair produce charged particles due to the Aharonov-Bohm (AB) interaction. We calculate the radiation pattern and power emitted for charged scalar particles. We extend the solenoid analysis to cosmic strings and find enhanced radiation from cusps and kinks on loops. We argue by analogy with the electromagnetic AB interaction that cosmic strings should emit photons due to the gravitational AB interaction of fields in the conical spacetime of a cosmic string. We calculate the emission from a kink and find that it is of similar order as emission from a cusp, but kinks are vastly more numerous than cusps and may provide a more interesting observational signature.

Jones-Smith, Katherine; Mathur, Harsh [CERCA, Department of Physics, Case Western Reserve University, Cleveland, Ohio 44106-7079 (United States); Vachaspati, Tanmay [CERCA, Department of Physics, Case Western Reserve University, Cleveland, Ohio 44106-7079 (United States); Institute for Advanced Study, Princeton, New Jersey 08540 (United States)

2010-02-15T23:59:59.000Z

234

Medical radiation protection in next decade  

Science Journals Connector (OSTI)

......towards increasing radiation safety levels. Whether...users whenever the radiation dose to the patient...human errors and software-related problems...global view of radiation protection in medicine...increasing radiation safety levels. Whether......

Madan M. Rehani; Eliseo Vano

2011-09-01T23:59:59.000Z

235

Coherence in Spontaneous Radiation Processes  

Science Journals Connector (OSTI)

By considering a radiating gas as a single quantum-mechanical system, energy levels corresponding to certain correlations between individual molecules are described. Spontaneous emission of radiation in a transition between two such levels leads to the emission of coherent radiation. The discussion is limited first to a gas of dimension small compared with a wavelength. Spontaneous radiation rates and natural line breadths are calculated. For a gas of large extent the effect of photon recoil momentum on coherence is calculated. The effect of a radiation pulse in exciting "super-radiant" states is discussed. The angular correlation between successive photons spontaneously emitted by a gas initially in thermal equilibrium is calculated.

R. H. Dicke

1954-01-01T23:59:59.000Z

236

Method for microbeam radiation therapy  

DOE Patents (OSTI)

A method is disclosed of performing radiation therapy on a patient, involving exposing a target, usually a tumor, to a therapeutic dose of high energy electromagnetic radiation, preferably X-ray radiation. The dose is in the form of at least two non-overlapping microbeams of radiation, each microbeam having a width of less than about 1 millimeter. Target tissue exposed to the microbeams receives a radiation dose during the exposure that exceeds the maximum dose that such tissue can survive. Non-target tissue between the microbeams receives a dose of radiation below the threshold amount of radiation that can be survived by the tissue, and thereby permits the non-target tissue to regenerate. The microbeams may be directed at the target from one direction, or from more than one direction in which case the microbeams overlap within the target tissue enhancing the lethal effect of the irradiation while sparing the surrounding healthy tissue. No Drawings

Slatkin, D.N.; Dilmanian, F.A.; Spanne, P.O.

1994-08-16T23:59:59.000Z

237

Anisotropic radiation elds: causality and quantum statistics  

E-Print Network (OSTI)

radiation transport 5 2.1 Radiation transport equation . . . . . . . . . . . . . . . . . . 5 2.2 Closures The transport of radiation through a medium is described by the radiation transport equation for the radiative is used to describe anisotropic radiation. Because the two moment equations do not form a closed set

Honingh, Aline

238

Influence of Extraterrestrial Radiation on Radiation Portal Monitors  

SciTech Connect

Cosmic radiation and solar flares can be a major source of background radiation at the Earth’s surface. This paper examines the relationship between extraterrestrial radiation and the detectable background in radiation portal monitors used for homeland security applications. Background radiation data from 13 radiation portal monitor facilities are examined and compared against external sources of data related to extraterrestrial radiation, including measurements at neutron monitors located at 53 cosmic-ray observatories around the Earth, four polar orbiting satellites, three geostationary satellites, ground-based geomagnetic field data from observatories around the Earth, a solar magnetic index, solar radio flux data, and sunspot activity data. Four-years (January 2003 through December 2006) of data are used in this study, which include the latter part of Solar Cycle 23 as solar activity was on the decline. The analysis shows a significant relationship between some extraterrestrial radiation and the background detected in the radiation portal monitors. A demonstrable decline is shown in the average gamma ray and neutron background at the radiation portal monitors as solar activity declined over the period of the study.

Keller, Paul E.; Kouzes, Richard T.

2009-06-01T23:59:59.000Z

239

Lesson 4 - Ionizing Radiation | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

4 - Ionizing Radiation 4 - Ionizing Radiation Lesson 4 - Ionizing Radiation Lesson Three showed that unstable isotopes emit energy as they become more stable. This energy is known as radiation. This lesson explores forms of radiation, where radiation is found, how we detect and measure radiation, what sources of radiation people are exposed to, whether radiation is harmful, and how we can limit our exposure. Specific topics covered in this lesson include: Types of radiation Non-ionizing Ionizing Forms of ionizing radiation Alpha particles Beta particles Gamma rays Radiation Decay chain Half-life Dose Radiation measurements Sources of radiation Average annual exposure Lesson 4 - Ionizing Radiation.pptx More Documents & Publications DOE-HDBK-1130-2008 DOE-HDBK-1130-2008 DOE-HDBK-1130-2007

240

Tumor bulk as a prognostic factor for the management of localized aggressive non-Hodgkin’s lymphoma: a survey of the Japan lymphoma radiation therapy group  

Science Journals Connector (OSTI)

Purpose: To identify the prognostic factors that specifically predict survival rates of patients with localized aggressive non-Hodgkin’s lymphoma (NHL). Methods and Materials: The survey was carried out at 25 radiation oncology institutions in Japan in 1998. The 5-year event-free (EFS) and overall survival rates (OAS) were calculated, and univariate and multivariate analyses were done to identify which of the following factors, namely, gender, age, performance status (PS), serum lactate dehydrogenase (LDH) level, Stage (I vs. II), tumor bulk (maximum diameter), and treatment, were significant from the viewpoint of prognosis. Results: A total of 1141 patients with Stage I and II NHL were treated by the Japanese Lymphoma Radiation Therapy Group between 1988 and 1992. Of them, 787 patients, who were treated using definitive radiotherapy with or without chemotherapy for intermediate- and high-grade lymphomas in working formulation, constituted the core of this study. Primary tumors arose mainly from extranodal organs (71%) in the head and neck (Waldeyer’s ring: 36% and sinonasal cavities: 9%). The factors associated with poorer prognosis were age over 60 years old (p radiation therapy alone (p Japan than in Western countries. Tumor bulk is an important prognostic factor in patients with localized aggressive extranodal NHL. Short course chemotherapy followed by radiation therapy was associated with prolonged survival in patients with localized aggressive \\{NHLs\\} of extranodal origin and 0–1 risk factor.

Masahiko Oguchi; Hiroshi Ikeda; Kouichi Isobe; Saeko Hirota; Masatoshi Hasegawa; Katsumasa Nakamura; Keisuke Sasai; Naofumi Hayabuchi

2000-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "radiation oncology feinberg" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


241

ARM ARM Atmospheric Radiation Measurement Atmospheric Radiation Measurement  

NLE Websites -- All DOE Office Websites (Extended Search)

An Integrated Column Description An Integrated Column Description of the Atmosphere An Integrated Column Description of the Atmosphere Tom Ackerman Chief Scientist Tom Ackerman Chief Scientist ARM ARM Atmospheric Radiation Measurement Atmospheric Radiation Measurement Pacific Northwest National Laboratory Pacific Northwest National Laboratory The "other" Washington ARM ARM Atmospheric Radiation Measurement Atmospheric Radiation Measurement Credits to Credits to * Ric Cederwall * Xiquan Dong * Chuck Long * Jay Mace * Mark Miller * Robin Perez * Dave Turner and the rest of the ARM science team * Ric Cederwall * Xiquan Dong * Chuck Long * Jay Mace * Mark Miller * Robin Perez * Dave Turner and the rest of the ARM science team ARM ARM Atmospheric Radiation Measurement Atmospheric Radiation Measurement Outline Outline * A little philosophy

242

Chronic Low Dose Radiation Effects on Radiation Sensitivity  

NLE Websites -- All DOE Office Websites (Extended Search)

Chronic Low Dose Radiation Effects on Radiation Sensitivity Chronic Low Dose Radiation Effects on Radiation Sensitivity and Chromosome Instability Induction in TK6 Cells Schwartz J.L. 1 , Jordan R. 1 , Slovic J. 1 , Moruzzi A. 1 , Kimmel R. 2 , and Liber, H.L. 3 1 University of Washington, Seattle, WA; 2 Fred Hutchinson Cancer Research Center, Seattle, WA; 3 Colorado State University, Fort Collins, Colorado There are a number of cell responses that can be detected after low dose radiation exposures including the adaptive response, low dose hypersensitivity, and induced genomic instability. The relationship between these different phenomena is unknown. In this study, we measured adaptive responses, low dose hypersensitivity, and induced genomic instability in a human B-lymphoblastoid cell model, TK6, where we could genetically modify radiation responses by either over-expression of BCL-2 or deletion of TP53. TK6

243

RADIATION LABORATO DISCLAIMER  

NLE Websites -- All DOE Office Websites (Extended Search)

R : R : . . . RADIATION LABORATO DISCLAIMER This report was prepared as an account of work sponsored by an agency of the United States Government. Neither the United States Government nor any agency Thereof, nor any of their employees, makes any warranty, express or implied, or assumes any legal liability or responsibility for the accuracy, completeness, or usefulness of any information, apparatus, product, or process disclosed, or represents that its use would not infringe privately owned rights. Reference herein to any specific commercial product, process, or service by trade name, trademark, manufacturer, or otherwise does not necessarily constitute or imply its endorsement, recommendation, or favoring by the United States Government or any

244

Radiation imaging apparatus  

DOE Patents (OSTI)

A radiation imaging system using a charge multiplier and a position sensitive anode in the form of periodically arranged sets of interconnected anode regions for detecting the position of the centroid of a charge cloud arriving thereat from the charge multiplier. Various forms of improved position sensitive anodes having single plane electrode connections are disclosed. Various analog and digital signal processing systems are disclosed, including systems which use the fast response of microchannel plates, anodes and preamps to perform scintillation pulse height analysis digitally. 15 figs.

Anger, H.O.; Martin, D.C.; Lampton, M.L.

1983-07-26T23:59:59.000Z

245

Radiation imaging apparatus  

DOE Patents (OSTI)

A radiation imaging system using a charge multiplier and a position sensitive anode in the form of periodically arranged sets of interconnected anode regions for detecting the position of the centroid of a charge cloud arriving thereat from the charge multiplier. Various forms of improved position sensitive anodes having single plane electrode connections are disclosed. Various analog and digital signal processing systems are disclosed, including systems which use the fast response of microchannel plates, anodes and preamps to perform scintillation pulse height analysis digitally.

Anger, Hal O. (Berkeley, CA); Martin, Donn C. (Berkeley, CA); Lampton, Michael L. (Berkeley, CA)

1983-01-01T23:59:59.000Z

246

Los Alamos Lab: Radiation Protection: Annual Occupational Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Annual Occupational Radiation Dosimetry Report Print information on Annual Occupational Radiation Dosimetry Report (pdf). This webpage provides information to help you understand the dose quantities being reported to you on your Annual Occupational Radiation Dosimetry Report. If you would like general information about radiation exposure, please refer to www.radiationanswers.org. Title 10 Code of Federal Regulation Part 835, Occupational Radiation Protection (10 CFR 835), requires assessment, recording and reporting of radiation doses to individuals who are exposed to sources of radiation or radioactive contamination. This includes assessing external exposure from a variety of radiation types, such as, beta, photon, and neutron radiation. External exposures may be uniform over the whole body or occur in a non-uniform (i.e., limited body location) fashion. Internal doses occur when radioactive material is taken into the body through ingestion, inhalation, absorption or wounds. The requirements include assessing doses to the whole body, skin, lens of the eyes, extremities and various organs and tissues.

247

Measurement of radiation impedance of stepped piston radiator  

Science Journals Connector (OSTI)

It was noted in a paper given in 1972 [A. H. Lubell J. Acoust. Soc. Am. 52 1310 (1972)] that the radiation mass of a stepped piston underwater loudspeaker was approximately half of the value expected from simple piston theory. Recently the integral equation approach was used to compute the radiation impedance for the Lubell Laboratories model 98 underwater loudspeaker and new measurements were made. This paper reviews the measurement and data reduction procedures and compares measured and theoretical radiation impedances. The original observation of reduced radiation mass is supported. A companion paper covers the integral equation computation. [This work was supported by Lubell Laboratories Inc.

Alan H. Lubell

1986-01-01T23:59:59.000Z

248

Radiation Control Program and Radiation Control Act (Nebraska)  

Energy.gov (U.S. Department of Energy (DOE))

This statute authorizes the state to implement a regulatory program for sources of radiation, and contains rules for the Department, licensing and registration, and taxation of radioactive materials.

249

Safety Around Sources of Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Keeping Exposure Low Keeping Exposure Low Working Safely Around Radioactive Contamination Types of Radiation Exposure Managing Radiation Emergencies Procedure Demonstration Is it safe to be around sources? Too much radiation exposure is harmful. The degree of radiation injury depends on the amount of radiation received and the time involved. In general, the higher the amount, the greater the severity of early effects (occurring within a few weeks) and the greater the possibility of late effects such as cancer. The BEIR V (Biological Effects of Ionizing Radiation) Committee of the National Research Council estimates that among 100,000 people exposed to a one-time dose of 10 rem (10,000 mrem) and followed over their life span, about 790 more would die of cancer than the estimated 20,000 cancer deaths that would be expected among a non-exposed group of the same size. NOTE: 10 rem = 100 millisieverts (100 mSv).

250

Radiation transport in inhomogeneous media  

SciTech Connect

Calculations of radiation transport in heated materials are greatly complicated by the presence of regions in which two or more materials are inhomogeneously mixed. This phenomenon is important in many systems, such as astrophysical systems where density clumps can be found in star-forming regions and molecular clouds. Laboratory experiments have been designed to test the modeling of radiation transport through inhomogeneous plasmas. A laser-heated hohlraum is used as a thermal source to drive radiation through polymer foam containing randomly distributed gold particles. Experimental measurements of radiation transport in foams with gold particle sizes ranging from 5-9 {mu}m to submicrometer diameters as well as the homogeneous foam case are presented. The simulation results of the radiation transport are compared to the experiment and show that an inhomogeneous transport model must be applied to explain radiation transport in foams loaded with 5 {mu}m diameter gold particles.

Keiter, Paul; Gunderson, Mark [Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States); Foster, John; Rosen, Paula; Comley, Andrew; Taylor, Mark [AWE Aldermaston, Reading, RG7 4PR (United Kingdom); Perry, Ted [Lawrence Livermore National Laboratory, Livermore, California 94550 (United States)

2008-05-15T23:59:59.000Z

251

Radiative Rayleigh-Taylor instabilities  

E-Print Network (OSTI)

We perform analytic linear stability analyses of an interface separating two stratified media threaded by a radiation flux, a configuration relevant in several astrophysical contexts. We develop a general framework for analyzing such systems, and obtain exact stability conditions in several limiting cases. In the optically thin, isothermal regime, where the discontinuity is chemical in nature (e.g.\\ at the boundary of a radiation pressure-driven H \\textsc{ii} region), radiation acts as part of an effective gravitational field, and instability arises if the effective gravity per unit volume toward the interface overcomes that away from it. In the optically thick "adiabatic" regime where the total (gas plus radiation) specific entropy of a Lagrangian fluid element is conserved,for example at the edge of radiation pressure-driven bubble around a young massive star, we show that radiation acts like a modified equation of state, and we derive a generalized version of the classical Rayleigh-Taylor stability conditi...

Jacquet, Emmanuel

2011-01-01T23:59:59.000Z

252

Cataractogenic effects of proton radiation  

E-Print Network (OSTI)

of proton radiation damage. The purpose of this study was (1) to determine the relative cataractogenic effects of different proton en- ergies, (2) to determine the relative cataractogenic effects of different radiation doses and (3) to determine... Laboratory in 1945 and 1946. Ten victims were exposed to various doses of moderately fast neutrons and hard gamma rays. In the eight survivors, two radiation cataracts resulted (15). In 1948 it was reported that five nuclear physicists with a common...

Kyzar, James Ronald

2012-06-07T23:59:59.000Z

253

Deterministic methods in radiation transport  

SciTech Connect

The Seminar on Deterministic Methods in Radiation Transport was held February 4--5, 1992, in Oak Ridge, Tennessee. Eleven presentations were made and the full papers are published in this report, along with three that were submitted but not given orally. These papers represent a good overview of the state of the art in the deterministic solution of radiation transport problems for a variety of applications of current interest to the Radiation Shielding Information Center user community.

Rice, A.F.; Roussin, R.W. (eds.)

1992-06-01T23:59:59.000Z

254

Radiation Emergency Medicine Fact Sheet  

NLE Websites -- All DOE Office Websites (Extended Search)

Improving Global Response Improving Global Response to Radiation Emergencies Improving Radiation Emergency Response Through Education and Specialized Expertise In the event of a radiological or nuclear incident, first responders as well as hospital and emergency management personnel must call on their knowledge and training to provide immediate and effective care for victims. Through practical, hands-on education programs, Oak Ridge Associated Universities (ORAU) is improving global response to radiation emergencies. In addition, dedicated 24/7 deployable teams of physicians, nurses, and health physicists from the Radiation Emergency Assistance Center/Training Site (REAC/TS), which is managed by ORAU for DOE/NNSA, provide expert medical management of radiological incidents

255

Presentation: Synchrotron Radiation Light Sources  

Energy.gov (U.S. Department of Energy (DOE))

A briefing to the Secretary's Energy Advisory Board on Synchrotron Radiation Light Sources delivered by Patricia Dehmer, U.S. Department of Energy

256

Reporting Occupational Radiation Exposure Data  

Energy.gov (U.S. Department of Energy (DOE))

IMPORTANT NOTICE: Due to increasing security concerns for the protection of Personnally Identifiable Information (PII), AU-23 has issued a policy statement regarding the submission of radiation...

257

RADIATION SAFETY COMMITTEE The Radiation Safety Committee shall advise the Provost on all policy matters relating to radiation safety;  

E-Print Network (OSTI)

RADIATION SAFETY COMMITTEE Functions The Radiation Safety Committee shall advise the Provost on all policy matters relating to radiation safety; formulate campus radiation safety policies in compliance the Risk Manager) monitor the performance of the Radiation Safety Officer as it relates to implementation

Sze, Lawrence

258

RADIATION APPLICATIONS INCORPORATED  

Office of Legacy Management (LM)

. <' ," . . * . RADIATION APPLICATIONS INCORPORATED . 370 Lexl.ngton Avenue New York 17# New York jq.5' L- Contract No. A T (30-l)-2093 with the United States Atom ic Energy Commission F O A M SEPARATION Progress Report for March, 1959 Abstract Appreciable cesium enrichment in the foam has been obtained using the system sodium tetraphenyl boron-Geigy reagent. Enrichment ratios varied from 1.5 to 3.5 depending upon operating conditions. The en- richment appears to depend on the ratio of the sodium tetraphenyl boron to Geigy reagent rather than on the absolute values of the indi- vidual concentrations. Further experiments are being conducted to verify and extend the range of results. Continuous countercurrent column operation has been continued.

259

Appendix F. Radiation Annual Site Environmental Report  

E-Print Network (OSTI)

from natural and human-made sources. People are exposed to naturally occurring radiation constantlyAppendix F. Radiation #12;Annual Site Environmental Report Appendix F. Radiation F-3 Appendix F. Radiation This appendix presents basic facts about radiation. The information is intended to be a basis

Pennycook, Steve

260

Biological Applications of Synchrotron Radiation:  

NLE Websites -- All DOE Office Websites (Extended Search)

Biological Applications of Synchrotron Radiation: Biological Applications of Synchrotron Radiation: An Evaluation of the State of the Field in 2002 A BioSync Report. Issued by the Structural Biology Synchrotron users Organization, October, 2002. 2 Table of Contents: Introduction .................................................................................................... 3 Abbreviations .................................................................................................. 5 Executive Summary ......................................................................................... 6 General Concerns ............................................................................................ 9 Synchrotron operations and maintenance ............................................... 9 NSLS, CHESS and the geographical distribution of beam lines

Note: This page contains sample records for the topic "radiation oncology feinberg" from the National Library of EnergyBeta (NLEBeta).
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261

RADIATION PROTECTION KEYWORDS: equivalent sphere  

E-Print Network (OSTI)

RADIATION PROTECTION KEYWORDS: equivalent sphere model, space radiation, organ dose IMPROVEMENT- alent sphere is used to represent the organ for a fast estimate of the organ dose. It has been found ~ESM! with an organ- specific constant radius parameter is used for fast estimates of the organ dose

Lin, Zi-wei

262

Radiation Environment Assimilation Model (DREAM).  

NLE Websites -- All DOE Office Websites (Extended Search)

DREAM tool increases space weather DREAM tool increases space weather predictions April 13, 2012 Predicting space weather improved by new DREAM modeling tool Earth's radiation belts can now be studied with a new modeling tool called Dynamic Radiation Environment Assimilation Model (DREAM). Researchers in LANL's Space Science and Applications (ISR-1) group are developing DREAM and described its current capabilities and applications in an article published in Space Weather, a journal of the American Geophysical Union. - 2 - Space environment and its hazards The space environment poses a number of radiation hazards to space systems and their occupants. Relativistic electrons, the dominant source of the radiation dose to spacecraft traveling in the outer radiation belts (3-7 Earth radii), have an electron flux

263

NREL: Solar Radiation Research - Facilities  

NLE Websites -- All DOE Office Websites (Extended Search)

Facilities Facilities Photo of two researchers standing on a platform near a solar tracker at the Solar Radiation Research Laboratory. The Solar Radiation Research Laboratory gathers solar radiation and meteorological data on South Table Mountain. NREL's Solar Radiation Research Laboratory (SRRL) has been collecting continuous measurements of basic solar radiation components since 1981. Since then, it has expanded its expertise to include integrated metrology, optics, electronics, and data acquisition capabilities. In addition, the SRRL provides facilities for outdoor performance testing of new research instrumentation and energy conversion devices such as photovoltaic modules. The SRRL is located on NREL's South Table Mountain site in Golden, Colorado, where it has excellent solar access because of its unrestricted

264

7 - Estimation of Radiation Doses  

Science Journals Connector (OSTI)

Abstract Radiation doses to the Japanese population from inhalation of contaminated air, external irradiation, terrestrial and marine food contamination are estimated and compared with other sources of anthropogenic (global fallout, Chernobyl accident), natural (radionuclides in food, cosmic radiation) and medical applications (X-ray tests, CT-tests, etc.) of ionizing radiation. The estimated doses from inhalation, ingestion of terrestrial and marine food, and radiation exposure from radioactive clouds and deposited radionuclides were generally below the levels which could cause health damage of the Japanese population, as well as of the world population. The estimated total radiation doses to fish and shellfish in coastal waters during the largest radionuclide releases were by a factor of 10 lower than the baseline safe level postulated for the marine organisms, therefore no harmful effects are expected for the marine ecosystem as well.

Pavel P. Povinec; Katsumi Hirose; Michio Aoyama

2013-01-01T23:59:59.000Z

265

Potential Health Hazards of Radiation | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Potential Health Hazards of Radiation Potential Health Hazards of Radiation Potential Health Hazards of Radiation Potential Health Hazards of Radiation More Documents &...

266

Molecular Pathways: Targeted ?-Particle Radiation Therapy  

Science Journals Connector (OSTI)

...and profibrotic cytokines. Radiation-induced malignancy can...1-5 Gy). Kyoji Furukawa (Radiation Effect Research Foundation, Hiroshima, Japan) reviewed the Japanese atomic...late effects of ionizing radiation exposure at low/moderate...

Kwamena E. Baidoo; Kwon Yong; and Martin W. Brechbiel

2013-02-01T23:59:59.000Z

267

Resistance of Marine Bacterioneuston to Solar Radiation  

Science Journals Connector (OSTI)

...of Marine Bacterioneuston to Solar Radiation Helene Agogue Fabien...after exposure to simulated solar radiation. Bacterioneuston...estimate of their screening capacity. Appl. Environ. Microbiol...D. P. 2000. Effects of solar UV-B radiation on aquatic...

Hélène Agogué; Fabien Joux; Ingrid Obernosterer; Philippe Lebaron

2005-09-01T23:59:59.000Z

268

Compton Sources of Electromagnetic Radiation  

SciTech Connect

When a relativistic electron beam interacts with a high-field laser beam, intense and highly collimated electromagnetic radiation will be generated through Compton scattering. Through relativistic upshifting and the relativistic Doppler effect, highly energetic polarized photons are radiated along the electron beam motion when the electrons interact with the laser light. For example, X-ray radiation can be obtained when optical lasers are scattered from electrons of tens-of-MeV beam energy. Because of the desirable properties of the radiation produced, many groups around the world have been designing, building, and utilizing Compton sources for a wide variety of purposes. In this review article, we discuss the generation and properties of the scattered radiation, the types of Compton source devices that have been constructed to date, and the prospects of radiation sources of this general type. Due to the possibilities of producing hard electromagnetic radiation in a device that is small compared to the alternative storage ring sources, it is foreseen that large numbers of such sources may be constructed in the future.

Geoffrey Krafft,Gerd Priebe

2011-01-01T23:59:59.000Z

269

DOE 2013 Occupational Radiation Exposure Report  

Office of Environmental Management (EM)

available on the U.S. Department of Energy Radiation Exposure Monitoring System Program Web Site at: http:energy.govehssoccupational-radiation-exposure Foreword iii MATTHEW B....

270

Annual DOE Occupational Radiation Exposure | 2008 Report  

Energy.gov (U.S. Department of Energy (DOE))

The DOE 2008 Occupational Radiation Exposure Report analyzes occupational radiation exposures at U.S. Department of Energy (DOE) facilities during 2008.

271

ANNUAL DOE OCCUPATIONAL RADIATION EXPOSURE | 2013 REPORT  

Energy.gov (U.S. Department of Energy (DOE))

The DOE 2013 Occupational Radiation Exposure Report analyzes occupational radiation exposures at U.S. Department of Energy (DOE) facilities during 2013.

272

10 CFR 835- Occupational Radiation Protection  

Energy.gov (U.S. Department of Energy (DOE))

The rules in this part establish radiation protection standards, limits, and program requirements for protecting individuals from ionizing radiation resulting from the conduct of DOE activities.

273

Code of Federal Regulations OCCUPATIONAL RADIATION PROTECTION  

Energy.gov (U.S. Department of Energy (DOE))

The rules in this part establish radiation protection standards, limits, and program requirements for protecting individuals from ionizing radiation resulting from the conduct of DOE activities.

274

Annual DOE Occupational Radiation Exposure | 2004 Report  

Energy.gov (U.S. Department of Energy (DOE))

The DOE 2004 Occupational Radiation Exposure Report analyzes occupational radiation exposures at U.S. Department of Energy (DOE) facilities during 2004.

275

12.815 Atmospheric Radiation, Fall 2005  

E-Print Network (OSTI)

Introduction to the physics of atmospheric radiation and remote sensing including use of computer codes. Radiative transfer equation including emission and scattering, spectroscopy, Mie theory, and numerical solutions. ...

Prinn, Ronald G.

276

Annual DOE Occupational Radiation Exposure | 2000 Report  

Energy.gov (U.S. Department of Energy (DOE))

The DOE 2000 Occupational Radiation Exposure Report analyzes occupational radiation exposures at U.S. Department of Energy (DOE) facilities during 2000.

277

Annual DOE Occupational Radiation Exposure | 1999 Report  

Energy.gov (U.S. Department of Energy (DOE))

The DOE Occupational Radiation Exposure Report, 1999 reports occupational radiation exposures incurred by individuals at DOE facilities during the calendar year 1999.

278

Annual DOE Occupational Radiation Exposure | 1974 Report  

Energy.gov (U.S. Department of Energy (DOE))

The Seventh Annual Report of Radiation Exposures for AEC & AEC Contractor Employees analyzes occupational radiation exposures at the Atomic Energy Commission (AEC) and its contractor employees during 1974.

279

Annual DOE Occupational Radiation Exposure | 1997 Report  

Energy.gov (U.S. Department of Energy (DOE))

The DOE Occupational Radiation Exposure Report, 1997 reports occupational radiation exposures incurred by individuals at U.S. Department of Energy (DOE) facilities during the calendar year 1997.

280

Annual DOE Occupational Radiation Exposure | 1995 Report  

Energy.gov (U.S. Department of Energy (DOE))

The DOE Occupational Radiation Exposure Report, 1995 reports occupational radiation exposures incurred by individuals at U.S. Department of Energy (DOE) facilities during the calendar year 1995.

Note: This page contains sample records for the topic "radiation oncology feinberg" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


281

Annual DOE Occupational Radiation Exposure | 1996 Report  

Energy.gov (U.S. Department of Energy (DOE))

The DOE Occupational Radiation Exposure Report, 1996 reports occupational radiation exposures incurred by individuals at U.S. Department of Energy (DOE) facilities during the calendar year 1996.

282

Annual DOE Occupational Radiation Exposure | 1998 Report  

Energy.gov (U.S. Department of Energy (DOE))

The DOE Occupational Radiation Exposure Report, 1998 reports occupational radiation exposures incurred by individuals at DOE facilities during the calendar year 1998.

283

Annual DOE Occupational Radiation Exposure | 2001 Report  

Energy.gov (U.S. Department of Energy (DOE))

The DOE 2001 Occupational Radiation Exposure Report analyzes occupational radiation exposures at U.S. Department of Energy (DOE) facilities during 2001.

284

Standards for Protection Against Radiation (Michigan)  

Energy.gov (U.S. Department of Energy (DOE))

This rule establishes standards for protection against radiation hazards. In addition to complying with requirements set forth, every reasonable effort should be made to maintain radiation levels...

285

Low Dose Radiation Research Program: Low Dose Radiation Effects in  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation Effects in Differentiating Human Lens Cells Radiation Effects in Differentiating Human Lens Cells E.A. Blakely1, M.P. McNamara1, P.Y. Chang1, K.A. Bjornstad1, D. Sudar1, and A.C. Thompson2 1Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California; 2Advanced Light Source Division, Lawrence Berkeley National Laboratory, Berkeley, California. Introduction The human lens is one of the most radiosensitive organs of the body. Cataract, the opacification of the lens, is a late-appearing response to radiation damage. There are few data available on the late radiation effects of exposure in space flight to charged particle beams, the most prevalent of which are protons. Basic research in this area is needed to integrate the responses of both critical and other representative tissues

286

NREL: Solar Radiation Research - Solar Radiation Research Laboratory  

NLE Websites -- All DOE Office Websites (Extended Search)

Solar Radiation Research Laboratory Photographs Solar Radiation Research Laboratory Photographs The Solar Radiation Research Laboratory (SRRL) houses more than 70 instruments to analyze and record solar radiation and surface meteorology data. Learn more about this equipment by exploring the photographs below. Click on a thumbnail to view the full image. Photo of researcher working on an instrument platform in front of the SRRL building. The SRRL is located on South Table Mountain in Golden, Colorado, at 39.74° N, 105.18° W, and 1,829 m AMSL. Photo of four researchers working on equipment atop the SRRL instrument deck. The SRRL's instrument deck is 96 ft long and 16 feet wide. Photo of two pyrheliometers mounted to an automatic sun-tracking base. These two SRRL pyrheliometers are mounted to automatically track the sun

287

Valproic Acid Use During Radiation Therapy for Glioblastoma Associated With Improved Survival  

SciTech Connect

Purpose: Valproic acid (VA) is an antiepileptic drug (AED) and histone deacetylase (HDAC) inhibitor taken by patients with glioblastoma (GB) to manage seizures, and it can modulate the biologic effects of radiation therapy (RT). We investigated whether VA use during RT for GB was associated with overall survival (OS). Methods and Materials: Medical records of 544 adults with GB were retrospectively reviewed. Analyses were performed to determine the association of Radiation Therapy Oncology Group recursive partitioning analysis (RTOG RPA) class, seizure history, and concurrent temozolomide (TMZ) and AED use during RT with OS. Results: Seizures before the end of RT were noted in 217 (40%) patients, and 403 (74%) were taking an AED during RT; 29 (7%) were taking VA. Median OS in patients taking VA was 16.9 months (vs 13.6 months taking another AED, P=.16). Among patients taking an AED during RT, OS was associated with VA (P=.047; hazard ratio [HR], 0.67; 95% confidence interval [CI], 0.27-1.07), and RTOG RPA class (P<.0001; HR, 1.49; 95% CI, 1.37-1.61). Of the 5 most common AEDs, only VA was associated with OS. Median OS of patients receiving VA and TMZ during RT was 23.9 months (vs 15.2 months for patients taking another AED, P=.26). When the analysis was restricted to patients who received concurrent TMZ, VA use was marginally associated with OS (P=.057; HR, 0.54; 95% CI, ?0.09 to 1.17), independently of RTOG RPA class and seizure history. Conclusions: VA use during RT for GB was associated with improved OS, independently of RTOG RPA, seizure history, and concurrent TMZ use. Further studies of treatment that combines HDAC inhibitors and RT are warranted.

Barker, Christopher A., E-mail: barkerc@mskcc.org [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Bishop, Andrew J.; Chang, Maria; Beal, Kathryn; Chan, Timothy A. [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States)] [Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York (United States)

2013-07-01T23:59:59.000Z

288

Actively driven thermal radiation shield  

DOE Patents (OSTI)

A thermal radiation shield for cooled portable gamma-ray spectrometers. The thermal radiation shield is located intermediate the vacuum enclosure and detector enclosure, is actively driven, and is useful in reducing the heat load to mechanical cooler and additionally extends the lifetime of the mechanical cooler. The thermal shield is electrically-powered and is particularly useful for portable solid-state gamma-ray detectors or spectrometers that dramatically reduces the cooling power requirements. For example, the operating shield at 260K (40K below room temperature) will decrease the thermal radiation load to the detector by 50%, which makes possible portable battery operation for a mechanically cooled Ge spectrometer.

Madden, Norman W. (Livermore, CA); Cork, Christopher P. (Pleasant Hill, CA); Becker, John A. (Alameda, CA); Knapp, David A. (Livermore, CA)

2002-01-01T23:59:59.000Z

289

Radiator Labs | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Radiator Labs Radiator Labs National Clean Energy Business Plan Competition Radiator Labs Columbia University More than 14 million housing units, or 10 percent of the national housing stock, is heated by steam and hot water. Steam heating, which represents the majority of this market, is particularly inefficient, and is characterized by a central source of steam generation with a convective distribution system via a network of pipes and radiators. There is no way to control heat transfer through this network, so building managers configure boiler systems to treat a building as a single zone keeping the coldest apartment above a minimum statutory temperature. This results in overheating of the other spaces in the building due to differences in exposure, level of insulation, distribution system heating,

290

Radiator Labs | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Competition » Radiator Labs Competition » Radiator Labs National Clean Energy Business Plan Competition Radiator Labs Columbia University More than 14 million housing units, or 10 percent of the national housing stock, is heated by steam and hot water. Steam heating, which represents the majority of this market, is particularly inefficient, and is characterized by a central source of steam generation with a convective distribution system via a network of pipes and radiators. There is no way to control heat transfer through this network, so building managers configure boiler systems to treat a building as a single zone keeping the coldest apartment above a minimum statutory temperature. This results in overheating of the other spaces in the building due to differences in exposure, level of insulation, distribution system heating,

291

Radiator Labs | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Competition » Radiator Labs Competition » Radiator Labs National Clean Energy Business Plan Competition Radiator Labs Columbia University More than 14 million housing units, or 10 percent of the national housing stock, is heated by steam and hot water. Steam heating, which represents the majority of this market, is particularly inefficient, and is characterized by a central source of steam generation with a convective distribution system via a network of pipes and radiators. There is no way to control heat transfer through this network, so building managers configure boiler systems to treat a building as a single zone keeping the coldest apartment above a minimum statutory temperature. This results in overheating of the other spaces in the building due to differences in exposure, level of insulation, distribution system heating,

292

ARM - Measurement - Radiative heating rate  

NLE Websites -- All DOE Office Websites (Extended Search)

govMeasurementsRadiative heating rate govMeasurementsRadiative heating rate ARM Data Discovery Browse Data Comments? We would love to hear from you! Send us a note below or call us at 1-888-ARM-DATA. Send Measurement : Radiative heating rate The heating rate due to the divergence of long and shortwave radiative flux. Categories Radiometric, Atmospheric State Instruments The above measurement is considered scientifically relevant for the following instruments. Refer to the datastream (netcdf) file headers of each instrument for a list of all available measurements, including those recorded for diagnostic or quality assurance purposes. External Instruments MOLTS : Model Output Location Time Series Datastreams MOLTS : Model Output Location Time Series Datastreams MOLTSEDASSNDCLASS1 : Model Output Loc. Time Ser. (MOLTS): EDAS

293

Radiation Leukaemongenesis at Low Doses  

NLE Websites -- All DOE Office Websites (Extended Search)

Leukaemongenesis at Low Doses Leukaemongenesis at Low Doses Simon Bouffler Health Protection Agency Abstract Myeloid leukaemias feature prominently among the cancers associated with human exposures to ionising radiation. The CBA mouse model of radiation-induced acute myeloid leukaemia (AML) has been used extensively for both quantitative and mechanistic studies. Loss of genetic material from chromosome 2 (chr2) is known to be associated with most radiation-induced AMLs. AML develops in CBA mice exposed to X- or γ-radiation, after a mean latency period of 18 months, with a maximal incidence of approximately 25% at 3Gy. A strong candidate AML-suppressor gene located within the commonly deleted region of chr2 has been identified, Sƒpil/PU.1. This gene suffers hemizygous loss and specific

294

ARM - Measurement - Aerosol backscattered radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

backscattered radiation backscattered radiation ARM Data Discovery Browse Data Comments? We would love to hear from you! Send us a note below or call us at 1-888-ARM-DATA. Send Measurement : Aerosol backscattered radiation The scattering of radiant energy into the hemisphere of space bounded by a plane normal to the direction of the incident radiation and lying on the same side as the incident ray. Categories Aerosols Instruments The above measurement is considered scientifically relevant for the following instruments. Refer to the datastream (netcdf) file headers of each instrument for a list of all available measurements, including those recorded for diagnostic or quality assurance purposes. ARM Instruments AOS : Aerosol Observing System MPL : Micropulse Lidar NEPHELOMETER : Nephelometer

295

Measurement of solar radiation exergy  

Science Journals Connector (OSTI)

Methods of estimating the energy of solar radiation during it conversion into other forms of energy-thermal, photoelectric, and chemical-during photosynthesis of plants are examined. Analytical expressions are gi...

I. I. Sventitskii; A. P. Grishin

2009-12-01T23:59:59.000Z

296

Plasma Radiation by Rough Surfaces  

Science Journals Connector (OSTI)

The recent observation of a peak of scattered radiation at the plasma frequency from thin metal foils irradiated with light can be explained in terms of a small amount of surface roughness of the foils.

Edward A. Stern

1967-12-04T23:59:59.000Z

297

Medical applications of synchrotron radiation  

SciTech Connect

Ever since the first diagnostic x-ray was done in the United States on February 3, 1896, the application of ionizing radiation to the field of medicine has become increasingly important. Both in clinical medicine and basic research the use of x-rays for diagnostic imaging and radiotherapy is now widespread. Radiography, angiography, CAT and PETT scanning, mammography, and nuclear medicine are all examples of technologies developed to image the human anatomy. In therapeutic applications, both external and internal sources of radiation are applied to the battle against cancer. The development of dedicated synchrotron radiation sources has allowed exciting advances to take place in many of these applications. The new sources provide tunable, high-intensity monochromatic beams over a wide range of energies which can be tailored to specific programmatic needs. This paper surveys those areas of medical research in which synchrotron radiation facilities are actively involved.

Thomlinson, W.

1991-10-01T23:59:59.000Z

298

High-let radiation carcinogenesis  

SciTech Connect

Recent results for neutron radiation-induced tumors are presented to illustrate the complexities of the dose-response curves for high-LET radiation. It is suggested that in order to derive an appropriate model for dose-response curves for the induction of tumors by high-LET radiation it is necessary to take into account dose distribution, cell killing and the susceptibility of the tissue under study. Preliminary results for the induction of Harderian gland tumors in mice exposed to various heavy ion beams are presented. The results suggest that the effectiveness of the heavy ion beams increases with increasing LET. The slopes of the dose-response curves for the different high-LET radiations decrease between 20 and 40 rads and therefore comparisons of the relative effectiveness should be made from data obtained at doses below about 20 to 30 rads.

Fry, R.J.M.; Powers-Risius, P.; Alpen, E.L.; Ainsworth, E.J.; Ullrich, R.L.

1982-01-01T23:59:59.000Z

299

Quantum Theory of Synchroton Radiation  

Science Journals Connector (OSTI)

The classical relativistic expression for the synchrotron radiation spectrum has been generalized to include quantum corrections up to second order in ??/E [1]. The modifications can be traced to the discrete ...

Heimo G. Latal

1979-01-01T23:59:59.000Z

300

FAQS Reference Guide –Radiation Protection  

Energy.gov (U.S. Department of Energy (DOE))

This reference guide has been developed to address the competency statements in the December 2003 edition of DOE-STD-1174-2003, Radiation Protection Functional Area Qualification Standard.

Note: This page contains sample records for the topic "radiation oncology feinberg" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


301

Radiation Incident on Tilted Collectors  

Science Journals Connector (OSTI)

For solar energy system design purposes, observations of solar radiation on a horizontal surface must be converted to values on a tilted energy collector. An empirical conversion relationship, introduced by Liu and Jordan (1960) and based on ...

P. J. Robinson

1981-12-01T23:59:59.000Z

302

Radiation dose in dental radiology  

Science Journals Connector (OSTI)

...The aim of this study was to compare radiation exposure in panoramic radiography (PR), dental CT, and digital volume tomography (DVT) ... at appropriate locations were exposed as in a dental examination. In PR...

M. Cohnen; J. Kemper; O. Möbes; J. Pawelzik; U. Mödder

2002-03-01T23:59:59.000Z

303

Posters Radiation Singularities, Multiple Scattering  

NLE Websites -- All DOE Office Websites (Extended Search)

mean C 1 0.75 and Levy index 1.35 (as empirically observed) and apply to it the Radiative Transfer Equation in the perfect scattering case. We have analytical and numerical...

304

MULTI-POINT RADIATION MONITOR  

SciTech Connect

A unique radiation monitor has been developed for performing wide-area field surveys for radiation sources. This device integrates the real-time output of multiple radiation detectors into a hand-held personal computer (e.g., a PDA) containing an intuitive graphical user interface. An independent hardware module supplies high voltage to the detectors and contains a rapid sampling system for transferring the detector count rates through an interface to the PDA. The imbedded firmware can be changed for various applications using a programmable memory card. As presently configured, the instrument contains a series of Geiger-Mueller (GM) tubes in a flexible detector string. This linear array of multiple sensors can be used by US Coast Guard and Customs container inspection personnel to measure radiation intensity in stacks of transport containers where physical access is impeded.

Hofstetter, K; Donna Beals, D; Ken Odell, K; Robert Eakle, R; Russell Huffman, R; Larry Harpring, L

2006-05-12T23:59:59.000Z

305

Survivable pulse power space radiator  

DOE Patents (OSTI)

A thermal radiator system is described for use on an outer space vehicle, which must survive a long period of nonuse and then radiate large amounts of heat for a limited period of time. The radiator includes groups of radiator panels that are pivotally connected in tandem, so that they can be moved to deployed configuration wherein the panels lie largely coplanar, and to a stowed configuration wherein the panels lie in a stack to resist micrometerorite damage. The panels are mounted on a boom which separates a hot power source from a payload. While the panels are stowed, warm fluid passes through their arteries to keep them warm enough to maintain the coolant in a liquid state and avoid embrittlement of material. The panels can be stored in a largely cylindrical shell, with panels progressively further from the boom being of progressively shorter length. 5 figs.

Mims, J.; Buden, D.; Williams, K.

1988-03-11T23:59:59.000Z

306

Ionizing Radiation Injury (South Carolina)  

Energy.gov (U.S. Department of Energy (DOE))

This legislation applies to employers that have more than one employee who engages in activities which involve the presence of ionizing radiation. Employers with less than three employees can...

307

Medical Applications of Synchrotron Radiation  

DOE R&D Accomplishments (OSTI)

Ever since the first diagnostic x-ray was done in the United States on February 3, 1896, the application of ionizing radiation to the field of medicine has become increasingly important. Both in clinical medicine and basic research the use of x-rays for diagnostic imaging and radiotherapy is now widespread. Radiography, angiography, CAT and PETT scanning, mammography, and nuclear medicine are all examples of technologies developed to image the human anatomy. In therapeutic applications, both external and internal sources of radiation are applied to the battle against cancer. The development of dedicated synchrotron radiation sources has allowed exciting advances to take place in many of these applications. The new sources provide tunable, high-intensity monochromatic beams over a wide range of energies which can be tailored to specific programmatic needs. This paper surveys those areas of medical research in which synchrotron radiation facilities are actively involved.

Thomlinson, W.

1991-10-00T23:59:59.000Z

308

International Conference Synchrotron Radiation Instrumentation SRI `94  

SciTech Connect

This report contains abstracts for the international conference on Synchrotron Radiation Instrumentation at Brookhaven National Laboratory.

Not Available

1994-10-01T23:59:59.000Z

309

Radiation Safety Guide For Ancillary Personnel  

E-Print Network (OSTI)

, facilities, and public safety staff) who occasionally work in areas posted with the radiation symbol rules, you can ensure your safety while working in areas posted with the radiation symbol. 1. Follow allRadiation Safety Guide For Ancillary Personnel University of Washington Radiation Safety Office 203

Wilcock, William

310

Patient radiation exposure during different kyphoplasty techniques  

Science Journals Connector (OSTI)

......could reduce dose and radiation-associated risk...the risk of developing radiation-induced stochastic...specific computer software is available, providing...developed at the Medical Radiation Laboratory of the Finnish...Radiation and Nuclear Safety (STUK)(12). The......

Denis Panizza; Massimo Barbieri; Francesco Parisoli; Luca Moro

2014-01-01T23:59:59.000Z

311

Radiation Exposure Monitoring Systems Data Reporting Guide  

Energy.gov (U.S. Department of Energy (DOE))

Instructions for preparing occupational exposure data for submittal to the Radiation Exposure Monitoring System (REMS) repository.

312

Liquid cooled fiber thermal radiation receiver  

DOE Patents (OSTI)

A radiation-to-thermal receiver apparatus for collecting radiation and converting it to thermal energy is disclosed. The invention includes a fibrous mat material which captures radiation striking the receiver. Captured radiation is removed from the fibrous mat material by a transparent fluid within which the material is bathed.

Butler, B.L.

1985-03-29T23:59:59.000Z

313

Risk Estimation; Background Radiation (Natural and Artificial )  

E-Print Network (OSTI)

-threshold mode estimate the response at lower doses. · The Committee on Biological Effects of Ionizing RadiationModule 9 Risk Estimation; Background Radiation (Natural and Artificial ) · sources of background radiation · various risk models. · estimating risk and on the sources of background radiation, both

Massey, Thomas N.

314

INSTRUCTION CONCERNING PRENATAL RADIATION EXPOSURE A. INTRODUCTION  

E-Print Network (OSTI)

/fetus exposed to radiation, a dose limit for the embryo/fetus, and suggestions for reducing radiation exposure and the Radiation Control Officer in writing that she is pregnant and the estimated date of conception.311, FAC, places different radiation dose limits on declared pregnant workers than on adult workers

Slatton, Clint

315

Radiation Safety Edward O'Connell  

E-Print Network (OSTI)

tissues) #12;Sources of Background Radiation Exposure · Naturally occurring radioactive materialsRadiation Safety Edward O'Connell Radiation Safety Officer Stony Brook University New York #12;STONY BROOK UNIVERSITY & U. HOSPITAL MEDICAL CENTER #12;Why Radiation Safety · Working with radioactive

316

Radiation Health Physics Four Year Plan  

E-Print Network (OSTI)

Radiation Health Physics Four Year Plan 2011-12 Radiation Health Physics (42 hrs) CH Grade Shielding Ext Dosimetry RHP 475 4 Project-Nuc Syst Design RHP 481 4 Radiation Protection Western Culture (3): RHP 483 4 Radiation Biology RHP 488 3 Radioecology Skills (12 hrs) CH Grade Writing I: WR 121 English

Tullos, Desiree

317

How air influences radiation dose deposition in multiwell culture plates: a Monte Carlo simulation of radiation geometry  

Science Journals Connector (OSTI)

......that this underdosage does not have a significant...related to a lack of electronic equilibrium. This is...Fig. 5b). MC calculations of the same plate geometry...Oncology Physics: A Handbook for Teachers and Students-Podgorsak...Comparison of dose calculation algorithms in slab phantoms......

Sebastia Sabater; Roberto Berenguer; Paloma Honrubia-Gomez; Miguel Rivera; Ana Nuñez; Esther Jimenez-Jimenez; Ana Martos; Carmen Ramirez-Castillejo

2014-09-01T23:59:59.000Z

318

Development and Validation of a Heart Atlas to Study Cardiac Exposure to Radiation Following Treatment for Breast Cancer  

SciTech Connect

Purpose: Cardiac toxicity is an important sequela of breast radiotherapy. However, the relationship between dose to cardiac structures and subsequent toxicity has not been well defined, partially due to variations in substructure delineation, which can lead to inconsistent dose reporting and the failure to detect potential correlations. Here we have developed a heart atlas and evaluated its effect on contour accuracy and concordance. Methods and Materials: A detailed cardiac computed tomography scan atlas was developed jointly by cardiology, cardiac radiology, and radiation oncology. Seven radiation oncologists were recruited to delineate the whole heart, left main and left anterior descending interventricular branches, and right coronary arteries on four cases before and after studying the atlas. Contour accuracy was assessed by percent overlap with gold standard atlas volumes. The concordance index was also calculated. Standard radiation fields were applied. Doses to observer-contoured cardiac structures were calculated and compared with gold standard contour doses. Pre- and post-atlas values were analyzed using a paired t test. Results: The cardiac atlas significantly improved contour accuracy and concordance. Percent overlap and concordance index of observer-contoured cardiac and gold standard volumes were 2.3-fold improved for all structures (p < 0.002). After application of the atlas, reported mean doses to the whole heart, left main artery, left anterior descending interventricular branch, and right coronary artery were within 0.1, 0.9, 2.6, and 0.6 Gy, respectively, of gold standard doses. Conclusions: This validated University of Michigan cardiac atlas may serve as a useful tool in future studies assessing cardiac toxicity and in clinical trials which include dose volume constraints to the heart.

Feng, Mary, E-mail: maryfeng@umich.ed [Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, Michigan (United States); Moran, Jean M. [Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, Michigan (United States); Koelling, Todd [Department of Internal Medicine, Division of Cardiology, University of Michigan Medical Center, Ann Arbor, Michigan (United States); Chughtai, Aamer [Department of Radiology, University of Michigan Medical Center, Ann Arbor, Michigan (United States); Chan, June L.; Freedman, Laura; Hayman, James A.; Jagsi, Reshma; Jolly, Shruti; Larouere, Janice; Soriano, Julie; Marsh, Robin; Pierce, Lori J. [Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, Michigan (United States)

2011-01-01T23:59:59.000Z

319

Low Dose Radiation Program: 2010 Low Dose Radiation Research Program  

NLE Websites -- All DOE Office Websites (Extended Search)

Low Dose Radiation Research Program Investigators' Workshop Low Dose Radiation Research Program Investigators' Workshop »» Event Slide Show More than 150 people attended this year's workshop, held April 12-14 at the Renaissance M Street Hotel in Washington, D.C. In addition to 34 plenary talks and more than 70 poster presentations made by the program investigators, participants heard guest speakers from the National Cancer Institute and from sister low-dose programs in Europe and Japan. Remarks from DOE Dr. Anna Palmisano, Associate Director, Office of Science, Director for Biological and Environmental Research (BER), welcomed the meeting participants, thanked Low Dose Radiation Research Program Manager Dr. Noelle Metting for her leadership, and acknowledged the importance of the Low Dose Program to DOE because of its unique focus and important role. She

320

Low Dose Radiation Research Program: Frequencies of Radiation-Induced  

NLE Websites -- All DOE Office Websites (Extended Search)

Frequencies of Radiation-Induced Chromosome Interchanges and Frequencies of Radiation-Induced Chromosome Interchanges and Randomness of Chromosome Territory Locations Relative to One Another. Authors: RK Sachs,§ MN Cornforth,‡ KM Greulich-Bode,* L Hlatky, and DJ Brenner|| Institutions: §Department of Mathematics, University of California, ‡University of Texas Medical Branch, *Department of Skin Carcinogenesis, German Cancer Research Center DFCI, Harvard Medical School, ||Center for Radiological Research, Columbia University. Leukemogenesis, and perhaps carcinogenesis in general, often involves specific chromosome translocations. Radiation-induced chromosome translocation frequencies are strongly influenced by how close participating chromosomes are to one another in an interphase cell nucleus. We sought to determine whether chromosomes in human peripheral blood

Note: This page contains sample records for the topic "radiation oncology feinberg" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


321

SCHIP: statistics for chromosome interphase positioning based on interchange data  

Science Journals Connector (OSTI)

......2Radiation Oncology Department, University of Texas Medical Branch Galveston, TX 77555, USA 3Mathematics Department...2Radiation Oncology Department, University of Texas Medical Branch, Galveston, TX 77555, USA, 3Mathematics Department......

Sergi Vives; Bradford Loucas; Mariel Vazquez; David J. Brenner; Rainer K. Sachs; Lynn Hlatky; Michael Cornforth; Javier Arsuaga

2005-07-01T23:59:59.000Z

322

BWR radiation control: plant demonstration  

SciTech Connect

The first year's progress is presented for a four-year program intended to implement and evaluate BRAC radiation reduction operational guidelines at the Vermont Yankee BWR and to document the results in sufficient detail to provide guidance to other BWR owners. Past operational, chemistry and radiation level data have been reviewed to provide a historical base of reference. Extensive sampling and chemistry monitoring systems have been installed to evaluate plant chemistry status and the effects of program implemented changes. Radiation surveys and piping gamma scans are being performed at targeted locations to quantify radiation level trends and to identify and quantify piping isotopics. Contact radiation levels on the recirculation line at Vermont Yankee have been increasing at a rate of 175 mR/h-EFPY since 1978. A materials survey of feedwater and reactor components in contact with the process liquid has been performed to identify sources of corrosion product release, particularly cobalt and nickel. A feedwater oxygen injection system has been installed to evaluate the effects of oxygen control on feedwater materials corrosion product releases. A baseline performance evaluation of the condensate treatment and reactor water cleanup systems has been completed. Data on organics and ionics at Vermont Yankee have been obtained. A methodology of BWR feedwater system layup during extended outages was developed, and an evaluation performed of layup and startup practices utilized at Vermont Yankee during the fall 1980 and 1981 refueling outages.

Palino, G.F.; Hobart, R.L.; Wall, P.S.; Sawochka, S.G.

1982-11-01T23:59:59.000Z

323

Radiation in molecular dynamic simulations  

SciTech Connect

Hot dense radiative (HDR) plasmas common to Inertial Confinement Fusion (ICF) and stellar interiors have high temperature (a few hundred eV to tens of keV), high density (tens to hundreds of g/cc) and high pressure (hundreds of Megabars to thousands of Gigabars). Typically, such plasmas undergo collisional, radiative, atomic and possibly thermonuclear processes. In order to describe HDR plasmas, computational physicists in ICF and astrophysics use atomic-scale microphysical models implemented in various simulation codes. Experimental validation of the models used to describe HDR plasmas are difficult to perform. Direct Numerical Simulation (DNS) of the many-body interactions of plasmas is a promising approach to model validation but, previous work either relies on the collisionless approximation or ignores radiation. We present a new numerical simulation technique to address a currently unsolved problem: the extension of molecular dynamics to collisional plasmas including emission and absorption of radiation. The new technique passes a key test: it relaxes to a blackbody spectrum for a plasma in local thermodynamic equilibrium. This new tool also provides a method for assessing the accuracy of energy and momentum exchange models in hot dense plasmas. As an example, we simulate the evolution of non-equilibrium electron, ion, and radiation temperatures for a hydrogen plasma using the new molecular dynamics simulation capability.

Glosli, J; Graziani, F; More, R; Murillo, M; Streitz, F; Surh, M

2008-10-13T23:59:59.000Z

324

solar radiation | OpenEI  

Open Energy Info (EERE)

radiation radiation Dataset Summary Description (Abstract): Monthly Average Solar Resource for flat-plate collectors tilted at latitude, for Mexico, Central America, and the Caribbean Islands. (Purpose): Provide information on the solar resource potential for the data domain. The insolation values represent the average solar energy available to a flat plate collector, such as a photovoltaic panel, oriented due south at an angle from horizontal equal to the latitude of the collector location. Source NREL Date Released January 31st, 2004 (10 years ago) Date Updated October 30th, 2007 (7 years ago) Keywords atmospheric water vapor Carribean Central America GEF. latitude tilt GIS Mexico NREL solar solar radiation SWERA TILT UNEP Data application/zip icon Download Shapefile (zip, 241.3 KiB)

325

Device for detecting ionizing radiation  

SciTech Connect

The present invention relates to ionizing radiation sensors, and , more particularly, to semiconductor spectrometers with thermoelectric cooling, and can most advantageously be used in mineral raw material exploration and evaluation under field conditions. The spectrometer comprises a vacuum chamber with an entrance window for passing the radiation therethrough. The vacuum chamber accommodates a thermoelectric cooler formed by a set of peltier elements. A heat conducting plate is mounted on the cold side of the thermoelectric cooler, and its hot side is provided with a radiator. Mounted on the heat conducting plate are sets of peltier elements, integral with the thermoelectric cooler and independent of one another. The peltier elements of these sets are stacked so as to develop the minimum temperature conditions on one set carrying a semiconductor detector and to provide the maximum refrigeration capacity conditions on the other set provided with the field-effect transistor mounted thereon.

Anatychuk, L.I.; Kharitonov, J.P.; Kusniruk, V.F.; Meir, V.A.; Melnik, A.P.; Ponomarev, V.S.; Skakodub, V.A.; Sokolov, A.D.; Subbotin, V.G.; Zhukovsky, A.N.

1980-10-28T23:59:59.000Z

326

A method for calculation of radiation quantities at all points in gamma radiation calibration fields  

Science Journals Connector (OSTI)

......Chi-square test in a gamma radiation calibration field was...dimensions) in a gamma radiation calibration field can...be used in dosimetry software of gamma radiation calibration fields...2000) Vienna: IAEA. Safety Reports Series, No......

S. M. Hosseini-Pooya; M. Khoshnoodi; A. Ansarinejad; F. Torkzadeh; M. Jafarizadeh

2008-03-01T23:59:59.000Z

327

Contrasting the direct radiative effect and direct radiative forcing of aerosols  

E-Print Network (OSTI)

The direct radiative effect (DRE) of aerosols, which is the instantaneous radiative impact of all atmospheric particles on the Earth's energy balance, is sometimes confused with the direct radiative forcing (DRF), which ...

Heald, Colette L.

328

1993 Radiation Protection Workshop: Proceedings  

SciTech Connect

The 1993 DOE Radiation Protection Workshop was conducted from April 13 through 15, 1993 in Las Vegas, Nevada. Over 400 Department of Energy Headquarters and Field personnel and contractors from the DOE radiological protection community attended the Workshop. Forty-nine papers were presented in eleven separate sessions: Radiological Control Manual Implementation, New Approaches to Instrumentation and Calibration, Radiological Training Programs and Initiatives, External Dosimetry, Internal Dosimetry, Radiation Exposure Reporting and Recordkeeping, Air Sampling and Monitoring Issues, Decontamination and Decommissioning of Sites, Contamination Monitoring and Control, ALARA/Radiological Engineering, and Current and Future Health Physics Research. Individual papers are indexed separately on the database.

Not Available

1993-12-31T23:59:59.000Z

329

Thermodynamics of Radiative Emission Processes  

Science Journals Connector (OSTI)

A basic assumption implicit in the application of thermodynamics to the electromagnetic field is that the laws of thermodynamics are locally valid for radiative emission and absorption processes. This means that a certain minimum amount of entropy must be created by the radiative process itself. It is shown, by considering the extreme case in which the spontaneous emission of a natural spectral line is the only process taking place, that this assumption is correct, and that its validity is essentially a consequence of the uncertainty principle as expressed by the reciprocal relationship between natural line breadth and lifetime.

M. A. Weinstein

1960-07-15T23:59:59.000Z

330

RTOG 0913: A Phase 1 Study of Daily Everolimus (RAD001) in Combination With Radiation Therapy and Temozolomide in Patients With Newly Diagnosed Glioblastoma  

SciTech Connect

Purpose: To determine the safety of the mammalian target of rapamycin inhibitor everolimus (RAD001) administered daily with concurrent radiation and temozolomide in newly diagnosed glioblastoma patients. Methods and Materials: Everolimus was administered daily with concurrent radiation (60 Gy in 30 fractions) and temozolomide (75 mg/m{sup 2} per day). Everolimus was escalated from 2.5 mg/d (dose level 1) to 5 mg/d (dose level 2) to 10 mg/d (dose level 3). Adjuvant temozolomide was delivered at 150 to 200 mg/m{sup 2} on days 1 to 5, every 28 days, for up to 12 cycles, with concurrent everolimus at the previously established daily dose of 10 mg/d. Dose escalation continued if a dose level produced dose-limiting toxicities (DLTs) in fewer than 3 of the first 6 evaluable patients. Results: Between October 28, 2010, and July 2, 2012, the Radiation Therapy Oncology Group 0913 protocol initially registered a total of 35 patients, with 25 patients successfully meeting enrollment criteria receiving the drug and evaluable for toxicity. Everolimus was successfully escalated to the predetermined maximum tolerated dose of 10 mg/d. Two of the first 6 eligible patients had a DLT at each dose level. DLTs included gait disturbance, febrile neutropenia, rash, fatigue, thrombocytopenia, hypoxia, ear pain, headache, and mucositis. Other common toxicities were grade 1 or 2 hypercholesterolemia and hypertriglyceridemia. At the time of analysis, there was 1 death reported, which was attributed to tumor progression. Conclusions: Daily oral everolimus (10 mg) combined with both concurrent radiation and temozolomide followed by adjuvant temozolomide is well tolerated, with an acceptable toxicity profile. A randomized phase 2 clinical trial with mandatory correlative biomarker analysis is currently under way, designed to both determine the efficacy of this regimen and identify molecular determinants of response.

Chinnaiyan, Prakash, E-mail: prakash.chinnaiyan@moffitt.org [Department of Radiation Oncology, Experimental Therapeutics and Cancer Imaging and Metabolism, H. Lee Moffitt Cancer Center, Tampa, Florida (United States); Won, Minhee [Radiation Therapy Oncology Group, Philadelphia, Pennsylvania (United States); Wen, Patrick Y. [Center for Neuro-Oncology, Dana-Farber/Brigham and Women's Cancer Center, Boston, Massachusetts (United States); Rojiani, Amyn M. [Department of Pathology, Medical College of Georgia, Augusta, Georgia (United States); Wendland, Merideth [Radiation Oncology, US Oncology-Willamette Valley Cancer Institute, Eugene, Oregon (United States); Dipetrillo, Thomas A. [Department of Radiation Oncology, Rhode Island Hospital, Providence, Rhode Island (United States); Corn, Benjamin W. [Department of Radiation Oncology, Tel Aviv Medical Center, Tel Aviv (Israel); Mehta, Minesh P. [Department of Radiation Oncology, University of Maryland, Baltimore, Maryland (United States)

2013-08-01T23:59:59.000Z

331

Radiation Related Terms Basic Terms  

E-Print Network (OSTI)

atoms. Radioactive Contamination Radioactive contamination is radioactive material distributed over some the effects of radiation. Radioactivity Radioactivity is the spontaneous transformation of an unstable atom or a disintegrations of an atom. Radioactive Material Radioactive Material is any material that contains radioactive

Vallino, Joseph J.

332

Radiation and Health Thormod Henriksen  

E-Print Network (OSTI)

of radioactivity from reactor accidents and fallout from nuclear explosions in the atmosphere. These subjects were interest is the effect of small radiation doses, given at a low dose rate. These studies are of importance for environmental problems as well as within cancer treatment. The group have close cooperations with professor

Johansen, Tom Henning

333

Electromagnetic Radiation in Accelerated Systems  

Science Journals Connector (OSTI)

A generally covariant set of electromagnetic field equations and associated constitutive relations is developed to deal with electromagnetic radiation in arbitrarily moving media. The equations are sufficiently general to include dispersive as well as nonisotropic media. Several special cases are investigated to illustrate the method and to demonstrate the consistency of the formulation.

J. L. Anderson and J. W. Ryon

1969-05-25T23:59:59.000Z

334

W. FIFTH AVE. RADIATION LAB  

E-Print Network (OSTI)

W. FIFTH AVE. NASA SPACE RADIATION LAB 958 ENERGY EFFICIENCY & CONSERVATION DIVISION THOMSON RD. E Development & Technology Transfer 490 H7 Energy Efficiency and Conservation Division 526 L5 Energy Sciences CAD Installation Complex 933 K2 Carpentry/Signs Shops 422 F6 Cavendish House 153 G7 Center

Ohta, Shigemi

335

Do freely falling bodies radiate?  

Science Journals Connector (OSTI)

... I have shown (unpublished) that it is possible to match this portion to a Schwarzschild metric which is valid for r > r0. The ... metric which is valid for r > r0. The Schwarzschild metric being static there is no radiation passing through it, so the moving dust ...

W. B. BONNOR

1976-09-23T23:59:59.000Z

336

Solid state radiative heat pump  

DOE Patents (OSTI)

A solid state radiative heat pump operable at room temperature (300 K) utilizes a semiconductor having a gap energy in the range of 0.03-0.25 eV and operated reversibly to produce an excess or deficit of change carriers as compared equilibrium. In one form of the invention an infrared semiconductor photodiode is used, with forward or reverse bias, to emit an excess or deficit of infrared radiation. In another form of the invention, a homogenous semiconductor is subjected to orthogonal magnetic and electric fields to emit an excess or deficit of infrared radiation. Three methods of enhancing transmission of radiation the active surface of the semiconductor are disclosed. In one method, an anti-refection layer is coated into the active surface of the semiconductor, the anti-reflection layer having an index of refraction equal to the square root of that of the semiconductor. In the second method, a passive layer is speaced trom the active surface of the semiconductor by a submicron vacuum gap, the passive layer having an index of refractive equal to that of the semiconductor. In the third method, a coupler with a paraboloid reflecting surface surface is in contact with the active surface of the semiconductor, the coupler having an index of refraction about the same as that of the semiconductor.

Berdahl, P.H.

1984-09-28T23:59:59.000Z

337

7, 72357275, 2007 Adaptive radiative  

E-Print Network (OSTI)

Discussions Two adaptive radiative transfer schemes for numerical weather prediction models V. Venema 1 , A numerical weather prediction (NWP) and climate models. The atmosphere and the land surface are complex-stream approximation. In most weather prediction models these parameterisation schemes are therefore called infre

Boyer, Edmond

338

Oncology Group (DeCOG)  

E-Print Network (OSTI)

Dacarbazine and interferon ? with or without interleukin 2 in metastatic melanoma: a randomized phase III

Universität Des Saarl

339

Panoramic Radiology: Oncologic Dentistry Considerations  

Science Journals Connector (OSTI)

Panoramic radiology can serve as an important input supporting ... they are also important (1) for planning dental treatment in preparation of the oral cavity...

2007-01-01T23:59:59.000Z

340

Radiation Detection Computational Benchmark Scenarios  

SciTech Connect

Modeling forms an important component of radiation detection development, allowing for testing of new detector designs, evaluation of existing equipment against a wide variety of potential threat sources, and assessing operation performance of radiation detection systems. This can, however, result in large and complex scenarios which are time consuming to model. A variety of approaches to radiation transport modeling exist with complementary strengths and weaknesses for different problems. This variety of approaches, and the development of promising new tools (such as ORNL’s ADVANTG) which combine benefits of multiple approaches, illustrates the need for a means of evaluating or comparing different techniques for radiation detection problems. This report presents a set of 9 benchmark problems for comparing different types of radiation transport calculations, identifying appropriate tools for classes of problems, and testing and guiding the development of new methods. The benchmarks were drawn primarily from existing or previous calculations with a preference for scenarios which include experimental data, or otherwise have results with a high level of confidence, are non-sensitive, and represent problem sets of interest to NA-22. From a technical perspective, the benchmarks were chosen to span a range of difficulty and to include gamma transport, neutron transport, or both and represent different important physical processes and a range of sensitivity to angular or energy fidelity. Following benchmark identification, existing information about geometry, measurements, and previous calculations were assembled. Monte Carlo results (MCNP decks) were reviewed or created and re-run in order to attain accurate computational times and to verify agreement with experimental data, when present. Benchmark information was then conveyed to ORNL in order to guide testing and development of hybrid calculations. The results of those ADVANTG calculations were then sent to PNNL for compilation. This is a report describing the details of the selected Benchmarks and results from various transport codes.

Shaver, Mark W.; Casella, Andrew M.; Wittman, Richard S.; McDonald, Ben S.

2013-09-24T23:59:59.000Z

Note: This page contains sample records for the topic "radiation oncology feinberg" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


341

Radiation protection standards: their evolution from science to philosophy  

Science Journals Connector (OSTI)

......require a new shielding evaluation (plan review), and they will certainly require...2001). Radiation protection standards: their evolution from science...control Radiation Monitoring standards Radiation Protection standards......

R. L. Dixon; Joel E. Gray; B. R. Archer; D. J. Simpkin

2005-12-20T23:59:59.000Z

342

History of the Stanford Synchrotron Radiation Lightsource | Stanford...  

NLE Websites -- All DOE Office Websites (Extended Search)

History of the Stanford Synchrotron Radiation Lightsource SPEAR Based on new applications of synchrotron radiation, SSRL began in 1973 as the Stanford Synchrotron Radiation Project...

343

Radiation shielding and dosimetry experiments updates in the SINBAD database  

Science Journals Connector (OSTI)

......characterisation of the radiation source, it describes...National Laboratory, Radiation Safety Information Computational...Internet Nuclear Physics Radiation Protection instrumentation Radiometry Research Software Validation...

I. Kodeli; H. Hunter; E. Sartori

2005-12-20T23:59:59.000Z

344

Radiation Management Act (Oklahoma) | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Radiation Management Act (Oklahoma) Radiation Management Act (Oklahoma) Radiation Management Act (Oklahoma) < Back Eligibility Utility Investor-Owned Utility Program Info State Oklahoma Program Type Environmental Regulations Provider Oklahoma Department of Environmental Quality This Act establishes The Department of Environmental Quality as the designated official agency of the State of Oklahoma for all regulatory activities for the use of atomic energy and sources of radiation, except for the use of sources of radiation by diagnostic x-ray facilities. It also states rules for permits and fees related to the establishment of standards for safe levels of protection against radiation; the maintenance and submission of records; the determination, prevention and control of radiation hazards; the reporting of radiation accidents; the handling,

345

Low Dose Radiation Research Program: Image Gallery  

NLE Websites -- All DOE Office Websites (Extended Search)

Image Gallery Image Gallery These are images, photographs, and charts presented or developed for Low Dose Radiation Research Investigators’ Meetings. They may be used for presentations or reports. To save, right click on the picture, then choose "Save picture as." U.S. annual per-capita effective radiation dose from various sources for 1980. various sources 1980 Enlarge Image. U.S. annual per-capita effective radiation dose from various sources for 2006. various sources 2006 Enlarge Image. U.S. annual per-capita effective radiation dose from man-made sources in the United States for 2006. man-made 2006 Enlarge Image. Ionizing Radiation Dose Ranges showing the wide range of radiation doses that humans experience (Rem) Enlarge Image. Ionizing Radiation Dose Ranges showing the wide range of radiation doses that humans experience

346

RADIATION PROTECTION QUALIFICATION STANDARD REFERENCE GUIDE  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Radiation Radiation Protection Qualification Standard Reference Guide MARCH 2009 ii This page intentionally left blank iii Table of Contents LIST OF FIGURES ..................................................................................................................... iv LIST OF TABLES ....................................................................................................................... iv ACRONYMS, ABBREVIATIONS and SYMBOLS ................................................................. v PURPOSE...................................................................................................................................... 1 SCOPE ...........................................................................................................................................

347

Cellular telephone-based radiation detection instrument  

DOE Patents (OSTI)

A network of radiation detection instruments, each having a small solid state radiation sensor module integrated into a cellular phone for providing radiation detection data and analysis directly to a user. The sensor module includes a solid-state crystal bonded to an ASIC readout providing a low cost, low power, light weight compact instrument to detect and measure radiation energies in the local ambient radiation field. In particular, the photon energy, time of event, and location of the detection instrument at the time of detection is recorded for real time transmission to a central data collection/analysis system. The collected data from the entire network of radiation detection instruments are combined by intelligent correlation/analysis algorithms which map the background radiation and detect, identify and track radiation anomalies in the region.

Craig, William W. (Pittsburg, CA); Labov, Simon E. (Berkeley, CA)

2011-06-14T23:59:59.000Z

348

Radiation Damage in Nanostructured Metallic Films  

E-Print Network (OSTI)

with favorable microstructures and to investigate their response to radiation. The goals of this thesis are to study the radiation responses of several nanostructured metallic thin film systems, including Ag/Ni multilayers, nanotwinned Ag and nanocrystalline Fe...

Yu, Kaiyuan

2013-04-15T23:59:59.000Z

349

Radiation Exposure from CT Examinations in Japan  

Science Journals Connector (OSTI)

Computed tomography (CT) is the largest source of medical radiation exposure to the general population, and is ... assess the current situation of CT use in Japan, and to investigate variations in radiation expos...

Yoshito Tsushima; Ayako Taketomi-Takahashi; Hiroyuki Takei…

2010-11-01T23:59:59.000Z

350

College of Health Sciences RAS Radiation Sciences  

E-Print Network (OSTI)

; excitation and ionization processes; selected nuclear reactions; basic radiation detection and dosimetry, and nuclear medical physics. Prereq or concur: RM/PHY 472G or consent of instructor. (Same as PHY/RM 546.) RAS 601 ADVANCED RADIATION DOSIMETRY. (2

MacAdam, Keith

351

Annual DOE Occupational Radiation Exposure | 1990 Report  

Energy.gov (U.S. Department of Energy (DOE))

The Twenty-third Annual Report of Radiation Exposures for DOE & DOE Contractor Employees analyzes occupational radiation exposures at the U.S. Department of Energy (DOE) and its contractor employees during 1990.

352

Annual DOE Occupational Radiation Exposure | 1991 Report  

Energy.gov (U.S. Department of Energy (DOE))

The Twenty-fourth Annual Report of Radiation Exposures for DOE & DOE Contractor Employees analyzes occupational radiation exposures at the U.S. Department of Energy (DOE) and its contractor employees during 1991.

353

Annual DOE Occupational Radiation Exposure | 1989 Report  

Energy.gov (U.S. Department of Energy (DOE))

The Twenty-second Annual Report of Radiation Exposures for DOE & DOE Contractor Employees analyzes occupational radiation exposures at the U.S. Department of Energy (DOE) and its contractor employees during 1989.

354

Annual DOE Occupational Radiation Exposure | 1986 Report  

Energy.gov (U.S. Department of Energy (DOE))

The Nineteenth Annual Report of Radiation Exposures for DOE & DOE Contractor Employees analyzes occupational radiation exposures at the U.S. Department of Energy (DOE) and its contractor employees during 1986.

355

Annual DOE Occupational Radiation Exposure | 1982 Report  

Energy.gov (U.S. Department of Energy (DOE))

The Fifteenth Annual Report of Radiation Exposures for DOE & DOE Contractor Employees analyzes occupational radiation exposures at the U.S. Department of Energy (DOE) and its contractor employees during 1982.

356

Annual DOE Occupational Radiation Exposure | 1983 Report  

Energy.gov (U.S. Department of Energy (DOE))

The Sixteenth Annual Report of Radiation Exposures for DOE & DOE Contractor Employees analyzes occupational radiation exposures at the U.S. Department of Energy (DOE) and its contractor employees during 1983.

357

Annual DOE Occupational Radiation Exposure | 1980 Report  

Energy.gov (U.S. Department of Energy (DOE))

The Thirteenth Annual Report of Radiation Exposures for DOE & DOE Contractor Employees analyzes occupational radiation exposures at the U.S. Department of Energy (DOE) and its contractor employees during 1980.

358

Annual DOE Occupational Radiation Exposure | 1979 Report  

Energy.gov (U.S. Department of Energy (DOE))

The Twelfth Annual Report of Radiation Exposures for DOE & DOE Contractor Employees analyzes occupational radiation exposures at the U.S. Department of Energy (DOE) and its contractor employees during 1979.

359

Annual DOE Occupational Radiation Exposure | 1987 Report  

Energy.gov (U.S. Department of Energy (DOE))

The Twentieth Annual Report of Radiation Exposures for DOE & DOE Contractor Employees analyzes occupational radiation exposures at the U.S. Department of Energy (DOE) and its contractor employees during 1987.

360

Annual DOE Occupational Radiation Exposure | 1985 Report  

Energy.gov (U.S. Department of Energy (DOE))

The Eighteenth Annual Report of Radiation Exposures for DOE & DOE Contractor Employees analyzes occupational radiation exposures at the U.S. Department of Energy (DOE) and its contractor employees during 1985.

Note: This page contains sample records for the topic "radiation oncology feinberg" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


361

Annual DOE Occupational Radiation Exposure | 1984 Report  

Energy.gov (U.S. Department of Energy (DOE))

The Seventeenth Annual Report of Radiation Exposures for DOE & DOE Contractor Employees analyzes occupational radiation exposures at the U.S. Department of Energy (DOE) and its contractor employees during 1984.

362

Order Module--RADIATION PROTECTION PROGRAMS GUIDE  

Energy.gov (U.S. Department of Energy (DOE))

The familiar level of this module is designed to provide the basic information related to DOEG 441.1-1C, Radiation Protection Programs Guide, as required in DOE-STD-1174-2003, Radiation Protection...

363

Annual DOE Occupational Radiation Exposure | 1981 Report  

Energy.gov (U.S. Department of Energy (DOE))

The Fourteenth Annual Report of Radiation Exposures for DOE & DOE Contractor Employees analyzes occupational radiation exposures at the U.S. Department of Energy (DOE) and its contractor employees during 1981.

364

Atmospheric State, Cloud Microphysics and Radiative Flux  

DOE Data Explorer (OSTI)

Atmospheric thermodynamics, cloud properties, radiative fluxes and radiative heating rates for the ARM Southern Great Plains (SGP) site. The data represent a characterization of the physical state of the atmospheric column compiled on a five-minute temporal and 90m vertical grid. Sources for this information include raw measurements, cloud property and radiative retrievals, retrievals and derived variables from other third-party sources, and radiative calculations using the derived quantities.

Mace, Gerald

365

Optimization of radiation protection: a bibliography  

SciTech Connect

This document provides a bibliography of radiation protection optimization documents. Abstracts, an author index, and a subject index are provided.

Tang, G.R.; Khan, T.A.; Sullivan, S.G.

1996-10-01T23:59:59.000Z

366

Radiation and Non-Hodgkin's Lymphoma  

Science Journals Connector (OSTI)

...bomb survivors in Japan and other epidemiological...quantitative estimates of radiation dose also fail to...bomb survivors in Japan and other epidemiological...quantitative estimates of radiation dose also fail to...bomb survivors in Japan and other epidemiol...quantitative estimates of radiation dose also fail to...

John D. Boice, Jr.

1992-10-01T23:59:59.000Z

367

Radiation-Resistant Reconnaissance Robot Introduction Design  

E-Print Network (OSTI)

are water-moderated. This type of reactor consists of a deep pool filled with water, uranium fuel rods. Radiation Resistance Control/Communication The objective of this project is to develop a submersible radiation- resistant, tether-operated robot for use in a water-moderated reactor pool. 1. Radiation

Provancher, William

368

Quantitative photoacoustic imaging in radiative transport regime  

E-Print Network (OSTI)

, radiative transport equation, inverse transport problem, interior data, Born approximation, iterative is accurately modeled by the radiative transport equation which describes the distribution of photons . The radiative transport equation for photon density u(x, v) can then be written as [9, 11, 77]: v · u(x, v) + a

Ren, Kui

369

On the Phenomenology of Tachyon Radiation  

E-Print Network (OSTI)

We present a brief overview of the different kinds of electromagnetic radiations expected to come from (or to be induced by) space-like sources (tachyons). New domains of radiation are here considered; and the possibility of experimental observation of tachyons via electromagnetic radiation is discussed.

Ron Folman; Erasmo Recami

1995-08-30T23:59:59.000Z

370

THE STANFORD SYNCHROTRON RADIATION LIGHTSOURCE STRATEGIC PLAN:  

NLE Websites -- All DOE Office Websites (Extended Search)

THE STANFORD SYNCHROTRON THE STANFORD SYNCHROTRON RADIATION LIGHTSOURCE STRATEGIC PLAN: 2013 - 2018 MEETING THE SCIENTIFIC CHALLENGES OF THE FUTURE FEBRUARY 2013 TABLE OF CONTENTS 1 Executive Summary ................................................................................................................................................. 1 2 Synchrotron Radiation - A Unique Tool .................................................................................................................. 1 3 Stanford Synchrotron Radiation Lightsource .......................................................................................................... 3 3.1 Looking into the Future: Building a New User Facility Paradigm at SSRL ....................................................... 4

371

Topics in radiation at accelerators: Radiation physics for personnel and environmental protection  

SciTech Connect

In the first chapter, terminology, physical and radiological quantities, and units of measurement used to describe the properties of accelerator radiation fields are reviewed. The general considerations of primary radiation fields pertinent to accelerators are discussed. The primary radiation fields produced by electron beams are described qualitatively and quantitatively. In the same manner the primary radiation fields produced by proton and ion beams are described. Subsequent chapters describe: shielding of electrons and photons at accelerators; shielding of proton and ion accelerators; low energy prompt radiation phenomena; induced radioactivity at accelerators; topics in radiation protection instrumentation at accelerators; and accelerator radiation protection program elements.

Cossairt, J.D.

1996-10-01T23:59:59.000Z

372

Radiation Chemistry of Ionic Liquids  

NLE Websites -- All DOE Office Websites (Extended Search)

Liquids Liquids James F. Wishart, Alison M. Funston, and Tomasz Szreder in "Molten Salts XIV" Mantz, R. A., et al., Eds.; The Electrochemical Society, Pennington, NJ, (2006) pp. 802-813. [Information about the volume (look just above this link)] Abstract: Ionic liquids have potentially important applications in nuclear fuel and waste processing, energy production, improving the efficiency and safety of industrial chemical processes, and pollution prevention. Successful use of ionic liquids in radiation-filled environments will require an understanding of ionic liquid radiation chemistry. For example, characterizing the primary steps of ionic liquid radiolysis will reveal radiolytic degradation pathways and suggest ways to prevent them or mitigate their effects on the properties of the material

373

BNL NASA Space Radiation Laboratory  

NLE Websites -- All DOE Office Websites (Extended Search)

Purpose: To use beams of heavy ions provided by the Booster accelerator at Brookhaven to study the effects of simulated space radiation on biological and physical systems, with the goal of developing methods and materials to reduce the risk to human beings on prolonged space missions of the effects of ionizing radiation Sponsor: National Aeronautics and Space Administration (NASA) Project cost $34 million over 4 years Operating costs Nearly $8 million per year in 2007 Features * beams of heavy ions extracted from the Booster accelerator with masses and energies similar to the cosmic rays encountered in space: * 1-billion electron volt (GeV)/nucleon iron-56 * 0.3-GeV/nucleon gold-97 * 0.6-GeV/nucleon silicon-28 * 1-GeV/nucleon protons * 1-GeV/nucleon titanium

374

Radiation Safety Work Control Form  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation Safety Work Control Form Radiation Safety Work Control Form (see instructions on pg-2) Rev July-2012 Area: Form #: Date: Preliminary Applicability Screen: (a) Will closing the beam line injection stoppers mitigate the radiological hazards introduced by the proposed work? Yes No (b) Can the closed state of the beam line injection stoppers be assured during the proposed work (ie., work does NOT involve injection stoppers or associated HPS)? Yes No If the answers to both questions are yes, the work can be performed safely under an SSRL RSWCF. If the answer to either question is no, then the work must be performed under a SPEAR3 RSWCF. Section 1: Description of work to be done, including date and time. (Person Responsible completes section)

375

Radiative Decay of the Muon  

Science Journals Connector (OSTI)

The radiative decay of the muon, ?+?e++?+?e+?¯?, has been measured using muons from the Columbia University Nevis synchrocyclotron. The decay products e+ and ? were observed at relative angles near 180°, using scintillation counters and two 9-in.×10-in. NaI crystals, which enabled simultaneous measurement of the positron and ? energies. The pulses from the crystals were displayed on oscilloscopes and photographed, and the measured amplitudes of these pulses were calibrated using the positron spectrum of the nonradiative decay. The two-dimensional energy spectrum for positrons and ?'s was obtained for about 900 events, after subtraction of background. This spectrum and the measured rate, obtained by normalizing to the nonradiative decay, were compared with theoretical predictions for the radiative decay. The results were in good agreement with the theory, within statistics, for the case of pure V-A coupling.

E. Bogart; E. DiCapua; P. Némethy; A. Strelzoff

1967-04-25T23:59:59.000Z

376

Standardisation of radiation portal monitor controls and readouts  

Science Journals Connector (OSTI)

......Standardisation of radiation portal monitor controls...numbering configuration of radiation portal monitor sensing...addition, second-party software that changes the alarm...Neutrons Nuclear Weapons Radiation Monitoring methods Radiation...Risk Assessment methods Safety Management methods standards......

M. Tinker

2010-10-01T23:59:59.000Z

377

Radiation safety design for the J-PARC project  

Science Journals Connector (OSTI)

......2001). Radiation safety design for the J-PARC...present status of the radiation safety design study for J-PARC...instrumentation Protons Radiation Dosage Radiation Monitoring...methods Risk Factors Software Software Validation......

H. Nakashima; Y. Nakane; F. Masukawa; N. Matsuda; T. Oguri; H. Nakano; N. Sasamoto; T. Shibata; T. Suzuki; T. Miura; M. Numajiri; N. Nakao; H. Hirayama; S. Sasaki

2005-12-20T23:59:59.000Z

378

Detoxification of Salmonella typhimurium Lipopolysaccharide by Ionizing Radiation  

Science Journals Connector (OSTI)

...efficiency of ionizing radiation in detoxifying...decreased with doses above 1 Mrad...efficiency of ionizing radiation in detoxifying...decreased with doses above 1 Mrad...the visible range. After radiation, the general...radiation doses through 20...

Joseph J. Previte; Y. Chang; H. M. El-Bisi

1967-05-01T23:59:59.000Z

379

Radiation Sterilization of Prototype Military Foods. III. Pork Loin  

Science Journals Connector (OSTI)

...Spearman-KMirber estimation of an LD5o...independent of the dose-response...with- 610 RADIATION STERILIZATION...values with radiation dose, and the fluctuating...commercial radiation process for...Werkowski. 1968. Estimation of radiation...

Abe Anellis; D. Berkowitz; C. Jarboe; H. M. El-Bisi

1969-10-01T23:59:59.000Z

380

Radiative muon absorption in oxygen  

Science Journals Connector (OSTI)

The photon spectrum from radiative absorption of negative muons in O16 has been measured with a high-resolution pair spectrometer. The integrated branching ratio for photons with energies greater than 57 MeV relative to the total muon absorption rate is (3.8±0.4)×10-5. The data are consistent with nuclear model calculations for a value of the induced pseudoscalar coupling in O16 of gP/gA=13.5±1.5.

A. Frischknecht; M. Döbeli; W. Stehling; G. Strassner; P. Truöl; J. C. Alder; C. Joseph; J. F. Loude; J. P. Perroud; D. Ruegger; M. T. Tran; H. Panke

1988-11-01T23:59:59.000Z

Note: This page contains sample records for the topic "radiation oncology feinberg" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


381

10th Radiation Physics and Protection Conference  

NLE Websites -- All DOE Office Websites (Extended Search)

Atomic Energy Authority National Network of Radiation Physics Atomic Energy Authority National Network of Radiation Physics 10 th Radiation Physics and Protection Conference Special Topic Elements of Regulating Nuclear and Radiation Activities Egyptian Law 26 -30 November 2010 To be held at EAEA Headquarter Nasr City Cairo - Egypt (www.rphysp.com) INVITATION The conference organizing committee invites scientists from the Atomic Energy , Research Centers , Universities Institutes , and all those involved in radiation Physics and its Applications in Egypt , Arab countries and abroad to participate in scientific activities of the conference . The official working language of the conference in English Conference Honorary Chairman Conference Scientific Secretary

382

Aharonov-Bohm radiation of fermions  

SciTech Connect

We analyze Aharonov-Bohm radiation of charged fermions from oscillating solenoids and cosmic strings. We find that the angular pattern of the radiation has features that differ significantly from that for bosons. For example, fermionic radiation in the lowest harmonic is approximately isotropically distributed around an oscillating solenoid, whereas for bosons the radiation is dipolar. We also investigate the spin polarization of the emitted fermion-antifermion pair. Fermionic radiation from kinks and cusps on cosmic strings is shown to depend linearly on the ultraviolet cutoff, suggesting strong emission at an energy scale comparable to the string energy scale.

Chu Yizen; Mathur, Harsh [CERCA, Department of Physics, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106-7079 (United States); Vachaspati, Tanmay [CERCA, Department of Physics, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106-7079 (United States); Institute for Advanced Study, Princeton, New Jersey 08540 (United States)

2010-09-15T23:59:59.000Z

383

Photon rockets and gravitational radiation  

E-Print Network (OSTI)

The absence of gravitational radiation in Kinnersley's ``photon rocket'' solution of Einstein's equations is clarified by studying the mathematically well-defined problem of point-like photon rockets in Minkowski space (i.e. massive particles emitting null fluid anisotro\\-pically and accelerating because of the recoil). We explicitly compute the (uniquely defined) {\\it linearized} retarded gravitational waves emitted by such objects, which are the coherent superposition of the gravitational waves generated by the motion of the massive point-like rocket and of those generated by the energy-momentum distribution of the photon fluid. In the special case (corresponding to Kinnersley's solution) where the anisotropy of the photon emission is purely dipolar we find that the gravitational wave amplitude generated by the energy-momentum of the photons exactly cancels the usual $1/r$ gravitational wave amplitude generated by the accelerated motion of the rocket. More general photon anisotropies would, however, generate genuine gravitational radiation at infinity. Our explicit calculations show the compatibility between the non-radiative character of Kinnersley's solution and the currently used gravitational wave generation formalisms based on post-Minkowskian perturbation theory.

T. Damour

1994-12-21T23:59:59.000Z

384

DarkLight radiation backgrounds  

SciTech Connect

We report measurements of photon and neutron radiation levels observed while transmitting a 0.43 MW electron beam through millimeter-sized apertures and during beam-on, but accelerating gradient RF-on, operation. These measurements were conducted at the Free-Electron Laser (FEL) facility of the Jefferson National Accelerator Laboratory (JLab) using a 100 MeV electron beam from an energy-recovery linear accelerator. The beam was directed successively through 6 mm, 4 mm, and 2 mm diameter apertures of length 127 mm in aluminum at a maximum current of 4.3 mA (430 kW beam power). This study was conducted to characterize radiation levels for experiments that need to operate in this environment, such as the proposed DarkLight Experiment. We find that sustained transmission of a 430 kW CW beam through a 2 mm aperture is feasible with manageable beam-related backgrounds. We also find that during beam-off, RF-on operation, field emission inside the niobium cavities of the accelerator cryomodules is the primary source of ambient radiation.

Kalantarians, N. [Department of Physics, Hampton University, Hampton VA 23668 (United States); Collaboration: DarkLight Collaboration

2013-11-07T23:59:59.000Z

385

DarkLight radiation backgrounds  

SciTech Connect

We report measurements of photon and neutron radiation levels observed while transmitting a 0.43 MW electron beam through millimeter-sized apertures and during beam-on, but accelerating gradient RF-on, operation. These measurements were conducted at the Free-Electron Laser (FEL) facility of the Jefferson National Accelerator Laboratory (JLab) using a 100 MeV electron beam from an energy-recovery linear accelerator. The beam was directed successively through 6 mm, 4 mm, and 2 mm diameter apertures of length 127 mm in aluminum at a maximum current of 4.3 mA (430 kW beam power). This study was conducted to characterize radiation levels for experiments that need to operate in this environment, such as the proposed DarkLight Experiment. We find that sustained transmission of a 430 kW CW beam through a 2 mm aperture is feasible with manageable beam-related backgrounds. We also find that during beam-off, RF-on operation, field emission inside the niobium cavities of the accelerator cryomodules is the primary source of ambient radiation.

Kalantarians, Narbe [University of Texas

2013-11-01T23:59:59.000Z

386

Radiation-tolerant imaging device  

DOE Patents (OSTI)

A barrier at a uniform depth for an entire wafer is used to produce imaging devices less susceptible to noise pulses produced by the passage of ionizing radiation. The barrier prevents charge created in the bulk silicon of a CCD detector or a semiconductor logic or memory device from entering the collection volume of each pixel in the imaging device. The charge barrier is a physical barrier, a potential barrier, or a combination of both. The physical barrier is formed by an SiO{sub 2} insulator. The potential barrier is formed by increasing the concentration of majority carriers (holes) to combine with the electron`s generated by the ionizing radiation. A manufacturer of CCD imaging devices can produce radiation-tolerant devices by merely changing the wafer type fed into his process stream from a standard wafer to one possessing a barrier beneath its surface, thus introducing a very small added cost to his production cost. An effective barrier type is an SiO{sub 2} layer. 7 figs.

Colella, N.J.; Kimbrough, J.R.

1996-11-19T23:59:59.000Z

387

Modified Method of Characteristics for Transient Radiative Transfer  

E-Print Network (OSTI)

conditions. The radiative transport equation is a hyperbolicTo solve the radiative transport equation for collimated

Katika, Kamal M.; Pilon, Laurent

2006-01-01T23:59:59.000Z

388

Sandia National Labs: PCNSC: Departments: Radiation and Nanosciences  

NLE Websites -- All DOE Office Websites (Extended Search)

Home About Us Departments Radiation, Nano Materials, & Interface Sciences > Radiation & Solid Interactions > Nanomaterials Sciences > Surface & Interface Sciences Semiconductor &...

389

Low Dose Radiation Program: Links - Online Literature  

NLE Websites -- All DOE Office Websites (Extended Search)

Online Literature Online Literature Journals, Books and other Publications Armed Forces Radiobiology Research Institute Chornobyl Center for Nuclear Safety Radioactive Waste and Radioecology "Insight" Magazine Central Research Institute of the Electric Power Industry (CRIEPI) News: Aiming at an information center on low dose radiation research Health Physics International Journal of Radiation Biology Iranian Journal of Radiation Research Journal of Radiological Protection National Council on Radiation Protection and Measurements Radiation Research U.S. Department of Energy (DOE) Information Bridge Reports Animal Cancer Tests and Human Cancer Risk Assessment: A Broad Perspective Effects of Ionizing Radiation: Atomic Bomb Survivors and Their Children (1945-1995) Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR

390

Information-geometric aspects of Hawking radiation  

E-Print Network (OSTI)

This paper illustrates the resemblance between the information-geometric structures of probability spaces and that of the discrete spectrum for Hawking radiation. The information geometry gives rise to a reconstruction of the standard formalism of quantum mechanics, while the discrete spectrum of Hawking radiation contributes to the semiclassical unitary evolution of Hawking radiation. If more realistic models of Hawking radiation are chosen, the information-geometric structures of the probability space for Hawking radiation can be constructed from some physical considerations. The constructed quantum formalism is consistent with both the unitary evolution of Hawking radiation in the semiclassical picture and the topology change of fuzzy horizon. These aspects of Hawking radiation can be connected to some general convictions of quantum gravity such as holography. A comparison with fuzzball propasal shows the limiation and effectiveness of this construction. We conclude that the infromation-geometric aspects show some possible ways bridging the gap between semiclassical models and quantum gravity.

Xiao-Kan Guo

2014-10-04T23:59:59.000Z

391

Calibration method for video and radiation imagers  

DOE Patents (OSTI)

The relationship between the high energy radiation imager pixel (HERIP) coordinate and real-world x-coordinate is determined by a least square fit between the HERIP x-coordinate and the measured real-world x-coordinates of calibration markers that emit high energy radiation imager and reflect visible light. Upon calibration, a high energy radiation imager pixel position may be determined based on a real-world coordinate of a moving vehicle. Further, a scale parameter for said high energy radiation imager may be determined based on the real-world coordinate. The scale parameter depends on the y-coordinate of the moving vehicle as provided by a visible light camera. The high energy radiation imager may be employed to detect radiation from moving vehicles in multiple lanes, which correspondingly have different distances to the high energy radiation imager.

Cunningham, Mark F. (Oak Ridge, TN); Fabris, Lorenzo (Knoxville, TN); Gee, Timothy F. (Oak Ridge, TN); Goddard, Jr., James S. (Knoxville, TN); Karnowski, Thomas P. (Knoxville, TN); Ziock, Klaus-peter (Clinton, TN)

2011-07-05T23:59:59.000Z

392

Quality Assurance Needs for Modern Image-Based Radiotherapy: Recommendations From 2007 Interorganizational Symposium on 'Quality Assurance of Radiation Therapy: Challenges of Advanced Technology'  

SciTech Connect

This report summarizes the consensus findings and recommendations emerging from 2007 Symposium, 'Quality Assurance of Radiation Therapy: Challenges of Advanced Technology.' The Symposium was held in Dallas February 20-22, 2007. The 3-day program, which was sponsored jointly by the American Society for Therapeutic Radiology and Oncology (ASTRO), American Association of Physicists in Medicine (AAPM), and National Cancer Institute (NCI), included >40 invited speakers from the radiation oncology and industrial engineering/human factor communities and attracted nearly 350 attendees, mostly medical physicists. A summary of the major findings follows. The current process of developing consensus recommendations for prescriptive quality assurance (QA) tests remains valid for many of the devices and software systems used in modern radiotherapy (RT), although for some technologies, QA guidance is incomplete or out of date. The current approach to QA does not seem feasible for image-based planning, image-guided therapies, or computer-controlled therapy. In these areas, additional scientific investigation and innovative approaches are needed to manage risk and mitigate errors, including a better balance between mitigating the risk of catastrophic error and maintaining treatment quality, complimenting the current device-centered QA perspective by a more process-centered approach, and broadening community participation in QA guidance formulation and implementation. Industrial engineers and human factor experts can make significant contributions toward advancing a broader, more process-oriented, risk-based formulation of RT QA. Healthcare administrators need to appropriately increase personnel and ancillary equipment resources, as well as capital resources, when new advanced technology RT modalities are implemented. The pace of formalizing clinical physics training must rapidly increase to provide an adequately trained physics workforce for advanced technology RT. The specific recommendations of the Symposium included the following. First, the AAPM, in cooperation with other advisory bodies, should undertake a systematic program to update conventional QA guidance using available risk-assessment methods. Second, the AAPM advanced technology RT Task Groups should better balance clinical process vs. device operation aspects-encouraging greater levels of multidisciplinary participation such as industrial engineering consultants and use-risk assessment and process-flow techniques. Third, ASTRO should form a multidisciplinary subcommittee, consisting of physician, physicist, vendor, and industrial engineering representatives, to better address modern RT quality management and QA needs. Finally, government and private entities committed to improved healthcare quality and safety should support research directed toward addressing QA problems in image-guided therapies.

Williamson, Jeffrey F. [Virginia Commonwealth University, Richmond, VA (United States)], E-mail: jwilliamson@mcvh-vcu.edu; Dunscombe, Peter B. [University of Calgary, Calgary, AB (Canada); Sharpe, Michael B. [Princess Margaret Hospital, Toronto, ON (Canada); Thomadsen, Bruce R. [University of Wisconsin, Madison, WI (United States); Purdy, James A. [University of California-Davis, Sacramento, CA (United States); Deye, James A. [National Cancer Institute, Bethesda, MD (United States)

2008-05-01T23:59:59.000Z

393

Fundamentals of health physics for the radiation-protection officer  

SciTech Connect

The contents of this book on health physics include chapters on properties of radioactive materials, radiation instrumentation, radiation protection programs, radiation survey programs, internal exposure, external exposure, decontamination, selection and design of radiation facilities, transportation of radioactive materials, radioactive waste management, radiation accidents and emergency preparedness, training, record keeping, quality assurance, and appraisal of radiation protection programs. (ACR)

Murphy, B.L.; Traub, R.J.; Gilchrist, R.L.; Mann, J.C.; Munson, L.H.; Carbaugh, E.H.; Baer, J.L.

1983-03-01T23:59:59.000Z

394

A new radiation shielding block material for radiation therapy  

SciTech Connect

In recent years, lead has been recognized as a source of environmental pollution; this includes lead use for radiation shielding in radiotherapy. We looked for a new material that could be a lead substitute. We chose a material composed of tungsten and resin. We compared the attenuation coefficient of the material with those of lead and Lipowitz's metal, and found the material has a higher attenuation coefficient than the other two. The material may be used as a substitute for lead because it is easy to fabricate and friendly to the environment.

Tajiri, Minoru; Sunaoka, Masayoshi; Fukumura, Akifumi; Endo, Masahiro [Radiological Technology Office, National Institute of Radiological Sciences 4-9-1, Anagawa, Inage-ku, Chiba 263-8555 (Japan); Department of Medical Physics, National Institute of Radiological Sciences 4-9-1, Anagawa, Inage-ku, Chiba 263-8555 (Japan)

2004-11-01T23:59:59.000Z

395

JOINT EPA/DOE STATEMENT: Radiation Monitors Confirm That No Radiation  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

EPA/DOE STATEMENT: Radiation Monitors Confirm That No EPA/DOE STATEMENT: Radiation Monitors Confirm That No Radiation Levels of Concern Have Reached the United States JOINT EPA/DOE STATEMENT: Radiation Monitors Confirm That No Radiation Levels of Concern Have Reached the United States March 18, 2011 - 12:00am Addthis WASHINGTON - The United States Government has an extensive network of radiation monitors around the country and no radiation levels of concern have been detected. The U.S. Environmental Protection Agency RadNet system is designed to protect the public by notifying scientists, in near real time, of elevated levels of radiation so they can determine whether protective action is required. The EPA's system has not detected any radiation levels of concern. In addition to EPA's RadNet system, the U.S. Department of Energy has

396

Radiation effects in the environment  

SciTech Connect

Although the Navajo possess substantial resource wealth-coal, gas, uranium, water-this potential wealth has been translated into limited permanent economic or political power. In fact, wealth or potential for wealth has often made the Navajo the victims of more powerful interests greedy for the assets under limited Navajo control. The primary focus for this education workshop on the radiation effects in the environment is to provide a forum where scientists from the nuclear science and technology community can share their knowledge toward the advancement and diffusion of nuclear science and technology issues for the Navajo public. The scientists will make an attempt to consider the following basic questions; what is science; what is mathematics; what is nuclear radiation? Seven papers are included in this report: Navajo view of radiation; Nuclear energy, national security and international stability; ABC`s of nuclear science; Nuclear medicine: 100 years in the making; Radon in the environment; Bicarbonate leaching of uranium; and Computational methods for subsurface flow and transport. The proceedings of this workshop will be used as a valuable reference materials in future workshops and K-14 classrooms in Navajo communities that need to improve basic understanding of nuclear science and technology issues. Results of the Begay-Stevens research has revealed the existence of strange and mysterious concepts in the Navajo Language of nature. With these research results Begay and Stevens prepared a lecture entitled The Physics of Laser Fusion in the Navajo language. This lecture has been delivered in numerous Navajo schools, and in universities and colleges in the US, Canada, and Alaska.

Begay, F.; Rosen, L.; Petersen, D.F.; Mason, C.; Travis, B. [Los Alamos National Lab., NM (United States); Yazzie, A. [Navajo Nation, Window Rock, AZ (United States). Dept. of History; Isaac, M.C.P.; Seaborg, G.T. [Lawrence Berkeley National Lab., CA (United States); Leavitt, C.P. [Univ. of New Mexico, Albuquerque, NM (United States). Dept. of Physics and Astronomy

1999-04-01T23:59:59.000Z

397

Solid-state radiation-emitting compositions and devices  

DOE Patents (OSTI)

The invention relates to a composition for the volumetric generation of radiation, wherein a first substance functions as a source of exciting radiation, and a second substance interacts with the exciting radiation to provide a second radiation. The compositions comprise a porous substrate which is loaded with: a source of exciting radiation, a component capable of emitting radiation upon interaction with the exciting radiation, or both. Preferably, the composition is an aerogel substrate loaded with both a source of exciting radiation, such as tritium, and a component capable of interacting with the exciting radiation, e.g., a phosphor, to produce radiation of a second energy. 4 figs.

Ashley, C.S.; Brinker, C.J.; Reed, S.; Walko, R.J.

1992-08-11T23:59:59.000Z

398

Solid-state radiation-emitting compositions and devices  

DOE Patents (OSTI)

The invention relates to a composition for the volumetric generation of radiation, wherein a first substance functions as a source of exciting radiation, and a second substance interacts with the exciting radiation to provide a second radiation. The compositions comprise a porous substrate which is loaded with: a source of exciting radiation, a component capable of emitting radiation upon interaction with the exciting radiation, or both. Preferably, the composition is an aerogel substrate loaded with both a source of exciting radiation, such as tritium, and a component capable of interacting with the exciting radiation, e.g., a phosphor, to produce radiation of a second energy.

Ashley, Carol S. (Albuquerque, NM); Brinker, C. Jeffrey (Albuquerque, NM); Reed, Scott (Albuquerque, NM); Walko, Robert J. (Albuquerque, NM)

1992-01-01T23:59:59.000Z

399

Solar Radiation Research Laboratory (SRRL)  

NLE Websites -- All DOE Office Websites (Extended Search)

Renewable Energy Laboratory Renewable Energy Laboratory Solar Radiation Research Laboratory (SRRL) Instrument Calibrations Weather Observations Measurement Research Support Measurements & Instrumentation Team Center for Electric & Hydrogen Technologies & Systems http://www.nrel.gov/srrl NREL * * * * 1617 Cole Boulevard * * * * Golden, Colorado 80401-3393 * * * * (303) 275-3000 Operated for the U.S. Department of Energy by Midwest Research Institute * * * * Battelle * * * * Bechtel Mission Provide a unique outdoor research facility for supporting renewable energy conversion technologies and climate change studies for the U.S. Department of Energy (DoE). Objectives * Provide Improved Methods for Radiometer Calibrations * Develop a Solar Resource Climate Database for Golden, Colorado

400

Radiative muon absorption in calcium  

Science Journals Connector (OSTI)

The photon spectrum from radiative absorption of negative muons in Ca40 has been measured with a high-resolution pair spectrometer. The data are analyzed in order to determine the induced pseudoscalar coupling constant gp in nuclear matter. When compared to models which use a realistic nuclear response function and avoid the closure approximation, a value of gp/gA=4.0±1.5 is obtained, which indicates a quenching of this coupling compared to the nucleonic value by a factor 0.57±0.25.

A. Frischknecht; W. Stehling; G. Strassner; P. Truöl; J. C. Alder; C. Joseph; J. F. Loude; J. P. Perroud; D. Ruegger; T. M. Tran; W. Dahme; H. Panke; R. Kopp

1985-11-01T23:59:59.000Z

Note: This page contains sample records for the topic "radiation oncology feinberg" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


401

Radiative Muon Capture in Calcium  

Science Journals Connector (OSTI)

The branching ratio relative to ordinary muon capture and the photon asymmetry relative to the muon-spin direction were measured for radiative muon capture in Ca40. For ~ 1200 photon events, the partial branching ratio is Rk>57 MeV=(21.1±1.4)×10-6, and the asymmetry for k>63.5 MeV is +0.90±0.50. A fit of the photon spectrum to the theory of Rood, Yano, and Yano gives the value gP?=(6.5±1.6)gA for the pseudoscalar-coupling constant. These results are in disagreement with earlier experiments.

R. D. Hart; C. R. Cox; G. W. Dodson; M. Eckhause; J. R. Kane; M. S. Pandey; A. M. Rushton; R. T. Siegel; R. E. Welsh

1977-08-15T23:59:59.000Z

402

RADIATION EFFECTS IN MATERIAL MICROSTRUCTURE.  

SciTech Connect

Next generation nuclear power systems, high-power particle accelerators and space technology will inevitably rely on higher performance materials that will be able to function in the extreme environments of high irradiation, high temperatures, corrosion and stress. The ability of any material to maintain its functionality under exposure to harsh conditions is directly linked to the material structure at the nano- and micro-scales. Understanding of the underlying processes is key to the success of such undertakings. This paper presents experimental results of the effects of radiation exposure on several unique alloys, composites and crystals through induced changes in the physio-mechanical macroscopic properties.

SIMOS,N.

2007-05-30T23:59:59.000Z

403

Sources Of Average Individual Radiation Exposure  

NLE Websites -- All DOE Office Websites (Extended Search)

Of Average Individual Radiation Exposure Of Average Individual Radiation Exposure Natural background Medical Consumer products Industrial, security, educational and research Occupational 0.311 rem 0.300 rem 0.013 rem 0.0003 rem 0.0005 rem Savannah River Nuclear Solutions, LLC, provides radiological protection services and oversight at the Savannah River Site (SRS). These services include radiation dose measurements for persons who enter areas where they may be exposed to radiation or radioactive material. The results are periodically reported to monitored individuals. The results listed are based on a radiation dose system developed by the International Commission on Radiation Protection. The system uses the terms "effective dose," "equivalent dose" and units of rem. You may be more familiar with the term "millirem" (mrem), which is 1/1000 of a rem.

404

Sandia National Laboratories: Research: Research Foundations: Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation Effects and High Energy Density Science Radiation Effects and High Energy Density Science Rings of Saturn, Sandia's workhorse pulsed-power machine. The Radiation Effects and High Energy Density Science Research Foundation seeks to advance science and engineering in the areas of radiation effects sciences, high energy density science, and pulsed-power science and technology to address critical national security issues. Why our work matters We address several issues key to nuclear security and maintaining a safe, secure, and effective nuclear stockpile. For example, radiation effects science ensures that engineered systems are able to operate as intended in the radiation environments they encounter. In addition, high energy density science validates models that are used to certify the performance of the

405

ORISE: DOE's Radiation Exposure Monitoring System (REMS)  

NLE Websites -- All DOE Office Websites (Extended Search)

Monitoring System (REMS) Monitoring System (REMS) ORISE maintains large database of radition exposure records for the U.S. Department of Energy ORISE staff monitoring radiation data for DOE Rule 10 CFR 835 establishes the U.S. Department of Energy's (DOE) occupational protection rule and requires assessment and recording of radiation doses to individuals who are exposed to sources of radiation or contamination. The Radiation Exposure Monitoring System (REMS) database is the radiation exposure data repository for all monitored DOE employees, contractors, subcontractors and members of the public. REMS maintains dose records for all monitored individuals dating back to 1969. Aggregated, site-specific data are available on the Radiation Exposure Monitoring System website for all years since 1986. Currently,

406

Low Dose Radiation Research Program: About  

NLE Websites -- All DOE Office Websites (Extended Search)

About About Background. Extensive research on the health effects of radiation using standard epidemiological and toxicological approaches has been done for decades to characterize responses of populations and individuals to high radiation doses, and to set exposure standards to protect both the public and the workforce. These standards were set using models that extrapolated from the cancers observed following exposure to high doses of radiation to predicted, but not measurable, changes in cancer frequency at low radiation doses. The use of models was necessary because of our inability to detect changes in cancer incidence following low doses of radiation. Historically, the predominant approach has been the Linear-no-Threshold model (see Wikipedia entry) and collective dose concept that assumes each unit of radiation, no

407

6 - Industrial Applications of Ionizing Radiation  

Science Journals Connector (OSTI)

The chapter summarizes the industrial applications of ionizing radiation. Ionizing radiation finds use in a variety of industrial applications such as wire and cable insulation, tire manufacturing, production of polymeric foams, heat-shrinkable films and tubings, curing of coatings, adhesives and composites, printing, and other technological development. It provides extensive information on EB process in wire and cable and tire technology. The chapter also provides discussion on EB process in the manufacture of polyolefin foams and heat-shrinkable materials. Detailed discussion on cross-linked PE pipes (PEX) including methods for production, irradiation, and its advantages, is presented. Other applications for ionizing radiation include sterilization of medical devices, hydrogels, radiation curing of polymeric composites, production of fluoroadditives, radiation-cured flexography, coatings, adhesives, paints, and printing inks. Keywords Ionizing radiation; tire manufacturing; wire and cable insulations; printing inks; polyolefin foams; heat-shrinkable materials; cross-linked PE pipes (PEX); hydrogels; flexography

Jiri George Drobny

2013-01-01T23:59:59.000Z

408

Apparatus and method for detecting gamma radiation  

DOE Patents (OSTI)

A high efficiency radiation detector is disclosed for measuring X-ray and gamma radiation from small-volume, low-activity liquid samples with an overall uncertainty better than 0.7% (one sigma SD). The radiation detector includes a hyperpure germanium well detector, a collimator, and a reference source. The well detector monitors gamma radiation emitted by the reference source and a radioactive isotope or isotopes in a sample source. The radiation from the reference source is collimated to avoid attenuation of reference source gamma radiation by the sample. Signals from the well detector are processed and stored, and the stored data is analyzed to determine the radioactive isotope(s) content of the sample. Minor self-attenuation corrections are calculated from chemical composition data. 4 figures.

Sigg, R.A.

1994-12-13T23:59:59.000Z

409

Uzbekistan Radiation Portal Monnitoring System  

SciTech Connect

The work proposed in this presentation builds on the foundation set by the DTRA funded demonstration project begun in 2000 and completed in December of 2003. This previous work consisted of two phases whose overall objective was to install portal radiation monitors at four select ports-of-entry in Uzbekistan (Tashkent International Airport, Gisht-Kuprik (Kazakhstan border), Alat (Turkmenistan border), and Termez (Afghanistan border)) in order to demonstrate their effectiveness in preventing the illicit trafficking of nuclear materials. The objectives also included developing and demonstrating capabilities in the design, installation, operation, training, and maintenance of a radiation portal monitoring system. The system and demonstration project has proved successful in many ways. An effective working relationship among the Uzbekistan Customs Services, Uzbekistan Border Guards, and Uzbekistan Institute of Nuclear Physics has been developed. There has been unprecedented openness with the sharing of portal monitor data with Lawrence Livermore National Laboratory. The system has proved to be effective, with detection of illicit trafficking, and, at Alat, an arrest of three persons illegally transporting radioactive materials into Turkmenistan. The demonstration project has made Uzbekistan a model nonproliferation state in Central Asia and, with an expanded program, places them in a position to seal a likely transit route for illicit nuclear materials. These results will be described. In addition, this work is currently being expanded to include additional ports-of-entry in Uzbekistan. The process for deciding on which additional ports-of-entry to equip will also be described.

Richardson, J; Knapp, R; Loshak, A; Yuldashev, B; Petrenko, V

2005-06-10T23:59:59.000Z

410

Development of Radiation Hard Sensors  

E-Print Network (OSTI)

The trackers of the present LHC experiments mainly use silicon pixel detectors in the innermost regions close to the interaction point, while silicon micro-strip detectors are used at larger radii. The next phases of the LHC will present new challenges for the operation of the tracking detectors in terms of radiation levels and data rates. For ATLAS, CMS and LHCb radiation levels will amount to levels of the order of hundreds of Mrad and 10^16 NIEL (1 MeV neutron equivalent per cm^2) in the innermost layers. Higher granularity and a reduction in material budget especially for the layers close to the IP are under development to further improve the impact parameter resolution. The choice of sensors for the trackers will be driven by the need to meet these requirements. A short overview on the status of the R&D on silicon sensors suitable for this challenging environment will be given, covering the presently used but also newly emerging technologies such as CMOS based silicon sensors. The capabilities of tec...

Riedler, P; The ATLAS collaboration

2013-01-01T23:59:59.000Z

411

Direct detector for terahertz radiation  

DOE Patents (OSTI)

A direct detector for terahertz radiation comprises a grating-gated field-effect transistor with one or more quantum wells that provide a two-dimensional electron gas in the channel region. The grating gate can be a split-grating gate having at least one finger that can be individually biased. Biasing an individual finger of the split-grating gate to near pinch-off greatly increases the detector's resonant response magnitude over prior QW FET detectors while maintaining frequency selectivity. The split-grating-gated QW FET shows a tunable resonant plasmon response to FIR radiation that makes possible an electrically sweepable spectrometer-on-a-chip with no moving mechanical optical parts. Further, the narrow spectral response and signal-to-noise are adequate for use of the split-grating-gated QW FET in a passive, multispectral terahertz imaging system. The detector can be operated in a photoconductive or a photovoltaic mode. Other embodiments include uniform front and back gates to independently vary the carrier densities in the channel region, a thinned substrate to increase bolometric responsivity, and a resistive shunt to connect the fingers of the grating gate in parallel and provide a uniform gate-channel voltage along the length of the channel to increase the responsivity and improve the spectral resolution.

Wanke, Michael C. (Albuquerque, NM); Lee, Mark (Albuquerque, NM); Shaner, Eric A. (Albuquerque, NM); Allen, S. James (Santa Barbara, CA)

2008-09-02T23:59:59.000Z

412

Solar radiation and human health  

Science Journals Connector (OSTI)

The Sun has played a major role in the development of life on Earth. In Western culture, people are warned against Sun exposure because of its adverse effects: erythema, photoimmunosuppression, photoageing, photocarcinogenesis, cataracts and photokeratitis. However, Sun exposure is also beneficial, since moderate doses give beneficial physiological effects: vitamin D synthesis, reduction of blood pressure and mental health. Shortage of Sun exposure may be even more dangerous to human health than excessive exposure. Avoiding Sun exposure leads to vitamin D deficiency which is associated not only with rickets and osteomalacia, but also with increased risk of cardiovascular disease, multiple sclerosis, rheumatoid arthritis, diabetes, influenza, many types of cancer and adverse pregnancy outcomes. Solar radiation induces nitric oxide release in tissue and immediate pigment darkening which certainly play important roles, although these are still unknown. Action spectra relevant for health are described. We will also review what is known about spectral and intensity variations of terrestrial solar radiation as well as its penetration through the atmosphere and into human skin and tissue.

Asta Juzeniene; Pål Brekke; Arne Dahlback; Stefan Andersson-Engels; Jörg Reichrath; Kristin Moan; Michael F Holick; William B Grant; Johan Moan

2011-01-01T23:59:59.000Z

413

Straddle Carrier Radiation Portal Monitoring  

SciTech Connect

U.S. Customs and Border Protection (CBP) is the primary enforcement agency protecting the nation’s ports of entry. CBP is enhancing its capability to interdict the illicit import of nuclear and radiological materials and devices that may be used by terrorists. Pacific Northwest National Laboratory (PNNL) is providing scientific and technical support to CBP in their goal to enable rapid deployment of nuclear and radiation detection systems at U. S. ports of entry to monitor 100% of the incoming international traffic and cargo while not adversely impacting the operations or throughput of the ports. The U.S. ports of entry include the following vectors: land border crossings, seaports, airports, rail crossings, and mail and express consignment courier facilities. U.S. Customs and Border Protection (CBP) determined that a screening solution was needed for Seaport cargo containers being transported by Straddle Carriers (straddle carriers). A stationary Radiation Portal Monitor (RPM) for Straddle Carriers (SCRPM) is needed so that cargo containers can be scanned while in transit under a Straddle Carrier. The Straddle Carrier Portal operational impacts were minimized by conducting a time-motion study at the Port, and adaptation of a Remotely Operated RPM (RO-RPM) booth concept that uses logical lighting schemes for traffic control, cameras, Optical Character Recognition, and wireless technology.

Andersen, Eric S.; Samuel, Todd J.; Mullen, O Dennis

2005-08-01T23:59:59.000Z

414

Solar and Infrared Radiation Station (SIRS) Handbook  

SciTech Connect

The Solar Infrared Radiation Station (SIRS) provides continuous measurements of broadband shortwave (solar) and longwave (atmospheric or infrared) irradiances for downwelling and upwelling components. The following six irradiance measurements are collected from a network of stations to help determine the total radiative flux exchange within the Atmospheric Radiation Measurement (ARM) Southern Great Plains (SGP) Climate Research Facility: • Direct normal shortwave (solar beam) • Diffuse horizontal shortwave (sky) • Global horizontal shortwave (total hemispheric) • Upwelling shortwave (reflected) • Downwelling longwave (atmospheric infrared) • Upwelling longwave (surface infrared)

Stoffel, T

2005-07-01T23:59:59.000Z

415

Radiative Effects of Cloud Inhomogeneity and  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiative Effects of Cloud Inhomogeneity and Geometric Association Over the Tropical Western Pacific Warm Pool X. Wu National Center for Atmospheric Research (a) Boulder, Colorado...

416

Radiation hormesis research findings and therapeutic applications  

Science Journals Connector (OSTI)

In 1982, Professor Thomas Don Luckey of Missouri University asserted 'radiation hormesis' in the journal Health Physics. Following his assertion, the CRIEPI initiated a research programme on radiation hormesis to confirm 'is it true or not'. Twelve years of research with 8â??14 universities in Japan produced fruitful results on radiation hormesis. Hormone response tests on rabbits, enzyme response tests on rats and mice, p53 gene responses from mice and rats and helper-T responses from human patients gave us impressive information to consider the therapeutic application of radiation hormesis.

Sadao Hattori

2005-01-01T23:59:59.000Z

417

Modelling of Radiative Transfer in Light Sources  

E-Print Network (OSTI)

. . . . . . . . . . . . . . . 30 2.5.3 Temperature distribution . . . . . . . . . . . . . . . . . . . . . . . . . 32 2-X radiative transition that is responsible for the sulfur lamp's bright sun-like spectrum #12;Contents 1

Eindhoven, Technische Universiteit

418

Posters Comparison of Stochastic Radiation Transfer Predictions  

NLE Websites -- All DOE Office Websites (Extended Search)

9 Posters Comparison of Stochastic Radiation Transfer Predictions with Multi-Filter Rotating Shadowband Radiometer Data N. Byrne and G. Ramanathan Science Applications...

419

Transport Test Problems for Radiation Detection Scenarios  

SciTech Connect

This is the final report and deliverable for the project. It is a list of the details of the test cases for radiation detection scenarios.

Shaver, Mark W.; Miller, Erin A.; Wittman, Richard S.; McDonald, Benjamin S.

2012-09-30T23:59:59.000Z

420

Nevada Test Site Radiation Protection Program  

SciTech Connect

Title 10 Code of Federal Regulations (CFR) 835, 'Occupational Radiation Protection', establishes radiation protection standards, limits, and program requirements for protecting individuals from ionizing radiation resulting from the conduct of U.S. Department of Energy (DOE) activities. 10 CFR 835.101(a) mandates that DOE activities be conducted in compliance with a documented Radiation Protection Program (RPP) as approved by DOE. This document promulgates the RPP for the Nevada Test Site (NTS), related (onsite or offsite) DOE National Nuclear Security Administration Nevada Site Office (NNSA/NSO) operations, and environmental restoration offsite projects.

Radiological Control Managers' Council, Nevada Test Site

2007-08-09T23:59:59.000Z

Note: This page contains sample records for the topic "radiation oncology feinberg" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


421

Accelerators for Testing Radiation Tolerances of Electronics...  

Office of Science (SC) Website

Text Size: A A A FeedbackShare Page Applicationinstrumentation: Accelerated beams test semiconductor devices for tolerances to space radiation. Developed at: Texas A&M...

422

ORISE: The Medical Aspects of Radiation Incidents  

NLE Websites -- All DOE Office Websites (Extended Search)

discussed in The Medical Aspects of Radiation Incidents are: basic health physics and dose estimation (US and SI units) treatment of whole body and acute local irradiation issues...

423

Photoprotection mechanisms against ultraviolet radiation in ...  

Science Journals Connector (OSTI)

Cells were cultivated under two different light treatments, photosynthetically active radiation (PAR) and PAR + UVR, and at two NaNO3 concentrations, mid ...

424

Meeting Report--NASA Radiation Biomarker Workshop  

E-Print Network (OSTI)

49.00 mSv as a result of the Chernobyl Nuclear Power Plantreactive protein (CRP) in Chernobyl radiation victims within

Straume, Tore

2008-01-01T23:59:59.000Z

425

Ion Beams - Radiation Effects Facility / Cyclotron Institute...  

NLE Websites -- All DOE Office Websites (Extended Search)

Ion Beams Available Beams Beam Change Times Measurements Useful Graphs Various ion beams have been developed specifically for the Radiation Effects Facility. These beams...

426

CRAD, Environmental Radiation Protection - December 7, 2009 ...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

December 7, 2009 Environmental Radiation Protection, Inspection Criteria, Approach, and Lines of Inquiry (HSS CRAD 64-36, Rev. 0) This Criteria Review and Approach Document (HSS...

427

Radiation Sources and Radioactive Materials (Connecticut)  

Energy.gov (U.S. Department of Energy (DOE))

These regulations apply to persons who receive, transfer, possess, manufacture, use, store, handle, transport or dispose of radioactive materials and/or sources of ionizing radiation. Some...

428

Radiation Machines and Radioactive Materials (Iowa)  

Energy.gov (U.S. Department of Energy (DOE))

These chapters describe general provisions and regulatory requirements; registration, licensure, and transportation of radioactive materials; and exposure standards for radiation protection.

429

Matter-Radiation Interactions in Extremes  

NLE Websites -- All DOE Office Websites (Extended Search)

for Discovery of Next-Generation Materials The Matter-Radiation Interactions in Extremes (MaRIE) experimental facility, will be used to discover and design the advanced...

430

Radiation Awareness TrainingRadiation Awareness Training Radioactive Material &Radioactive Material &  

E-Print Network (OSTI)

quarterly · Radioactive waste retrieval, storage, disposal · Dosimetry exchange · Leak tests of sealedRadiation Awareness TrainingRadiation Awareness Training Radioactive Material &Radioactive Material, Chemistry, Physics, Applied Physiology · Radioactive Material ­ Sealed Sources, Unsealed Sources (liquid

Sherrill, David

431

Solar-radiation-maintained glacier recession on Kilimanjaro drawn from combined ice-radiation geometry modeling  

E-Print Network (OSTI)

Solar-radiation-maintained glacier recession on Kilimanjaro drawn from combined ice of Massachusetts, Amherst, Massachusetts, USA Georg Kaser Tropical Glaciology Group, Department of Geography retreat during the twentieth century. To evaluate the role of solar radiation in maintaining glacier

Massachusetts at Amherst, University of

432

Radiation damage effects on detectors and eletronic devices in harsh radiation environment  

E-Print Network (OSTI)

Radiation damage effects represent one of the limits for technologies to be used in harsh radiation environments as space, radiotherapy treatment, high-energy phisics colliders. Different technologies have known tolerances to different radiation fields and should be taken into account to avoid unexpected failures which may lead to unrecoverable damages to scientific missions or patient health.

Fiore, S

2015-01-01T23:59:59.000Z

433

76Radiation Dose and Dose Rate Radiation is measured in two  

E-Print Network (OSTI)

Seiverts per year. Hasty reports about the devastating Japan 2011 nuclear power plant radiation leakages have by Concorde, what are the total radiation doses for a passenger in each case? Problem 3 - The Japan 2011 earthquake damaged several nuclear reactors, causing radiation leakage across northern Japan. On March 22

434

VII. SOLAR RADIATION DATA COMPARISONS In this section some of the solar radiation data  

E-Print Network (OSTI)

18 VII. SOLAR RADIATION DATA COMPARISONS In this section some of the solar radiation data gathered by the UO Solar Monitoring Network is presented in tabular and pictorial form and related to similar information from other Western U.S. sites. A comparison of the amount of incident solar radiation is made us

Oregon, University of

435

33. Radioactivity and radiation protection 1 33. RADIOACTIVITY AND RADIATION PROTECTION  

E-Print Network (OSTI)

a conservative estimate for the value of the protection quantity. · Ambient dose equivalent, H(10) (unit: sievert): The dose equivalent at a point in a radiation field that would be produced by the corresponding expanded33. Radioactivity and radiation protection 1 33. RADIOACTIVITY AND RADIATION PROTECTION Revised

436

Coherent Synchrotron Radiation: Theory and Simulations.  

SciTech Connect

The physics of coherent synchrotron radiation (CSR) emitted by ultra-relativistic electron bunches, known since the last century, has become increasingly important with the development of high peak current free electron lasers and shorter bunch lengths in storage rings. Coherent radiation can be described as a low frequency part of the familiar synchrotron radiation in bending magnets. As this part is independent of the electron energy, the fields of different electrons of a short bunch can be in phase and the total power of the radiation will be quadratic with the number of electrons. Naturally the frequency spectrum of the longitudinal electron distribution in a bunch is of the same importance as the overall electron bunch length. The interest in the utilization of high power radiation from the terahertz and far infrared region in the field of chemical, physical and biological processes has led synchrotron radiation facilities to pay more attention to the production of coherent radiation. Several laboratories have proposed the construction of a facility wholly dedicated to terahertz production using the coherent radiation in bending magnets initiated by the longitudinal instabilities in the ring. Existing synchrotron radiation facilities also consider such a possibility among their future plans. There is a beautiful introduction to CSR in the 'ICFA Beam Dynamics Newsletter' N 35 (Editor C. Biscari). In this paper we recall the basic properties of CSR from the theory and what new effects, we can get from the precise simulations of the coherent radiation using numerical solutions of Maxwell's equations. In particular, transverse variation of the particle energy loss in a bunch, discovered in these simulations, explains the slice emittance growth in bending magnets of the bunch compressors and transverse de-coherence in undulators. CSR may play same the role as the effect of quantum fluctuations of synchrotron radiation in damping rings. It can limit the minimum achievable emittance in the synchrotron light sources for short bunches.

Novokhatski, Alexander; /SLAC

2012-03-29T23:59:59.000Z

437

BNL NASA Space Radiation Laboratory  

NLE Websites -- All DOE Office Websites (Extended Search)

Dosimetry Calibration: Primary Ion Chamber Dosimetry Calibration: Primary Ion Chamber Dosimetry Calibration: Secondary Ion Chamber Dosimetry Calibration: Secondary Ion Chamber with Gain Dosimetry Calibration: Scintillator Based Dosimetry Dosimetry Calibration: Primary Ion Chamber The primary method of calibrating the dose delivered at NSRL is via a small ion chamber called a "Calibration Ion Chamber" (aka EGG counter) produced by Far West Technology. This is an air-filled bulb with electrodes for collecting ionization inside a tissue-equivalent plastic cap. The Calibration Ion Chamber is sent back to the manufacturer yearly to be calibrated using a standard gamma ray source (Cs-137). The calibration is based on a standard defied by the International Commission on Radiation Units and Measurements (ICRU) and reported in their ICRU Report 59, 15 December 1998.

438

BNL NASA Space Radiation Laboratory  

NLE Websites -- All DOE Office Websites (Extended Search)

First Time Users Guide First Time Users Guide The following is a collection of useful facts that First Time Users of NSRL should familiarize themselves with. If you have any questions, contact the NSRL Liaison Physicist (631-344-3072 or 631-344-5830). You MUST have a dry run of your experiment before conducting your first NSRL run. When planning an exposure the time you need for each sample exposure should include time to change samples. If RHIC is running, the sample changing time is approximately 7 minutes. If RHIC is not running, time to change samples is only about 4 minutes. The size of the radiation field that can uniformly expose a set of samples can be as large as 20 x 20 cm2 for most ions and energies. By special request, the NSRL beam can operate in Large Beam mode with a 60 x 60 cm2 usable beam size.

439

Magnetically focused liquid drop radiator  

DOE Patents (OSTI)

A magnetically focused liquid drop radiator for application in rejecting energy from a spacecraft, characterized by a magnetizable liquid or slurry disposed in operative relationship within the liquid droplet generator and its fluid delivery system, in combination with magnetic means disposed in operative relationship around a liquid droplet collector of the LDR. The magnetic means are effective to focus streams of droplets directed from the generator toward the collector, thereby to assure that essentially all of the droplets are directed into the collector, even though some of the streams may be misdirected as they leave the generator. The magnetic focusing means is also effective to suppress splashing of liquid when the droplets impinge on the collector.

Botts, T.E.; Powell, J.R.; Lenard, R.

1984-12-10T23:59:59.000Z

440

Alpha-beta radiation detector  

DOE Patents (OSTI)

The invention is based in part on the discovery that a plastic housing that is lightweight is surprisingly efficient inasmuch as background signals from any gamma radiation are significantly reduced by using a plastic housing instead of a metal housing. A further aspect of the present invention is the profile of the housing as a bi-linear approximation to a parabola resulting in full optical response from any location on the scintillation material to the photomultiplier tube. A yet further aspect of the present invention is that the survey probe is resistant to magnetic fields. A yet further aspect of the present invention is the use of a snap-fit retaining bracket that overcomes the need for multiple screws.

Fleming, Dale M. (Richland, WA); Simmons, Kevin L. (Kennewick, WA); Froelich, Thomas J. (West Richland, WA); Carter, Gregory L. (Richland, WA)

1998-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "radiation oncology feinberg" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


441

Radiation injury to the heart  

SciTech Connect

For the RTOG Consensus Conference on Late Effects of Cancer Treatment we summarize the clinical manifestations of cardiac complications appearing months to years following incidental irradiation of the heart during treatment of thoracic neoplasms. The most common effects present as pericardial disease, however, it is becoming more clear that precocious or accelerated coronary artery disease is an important late effect, especially in patients treated with radiation before the age of 21 years. To the extent it is known, the pathophysiology of the various syndromes is described and the extensive literature on dose, volume, and fractionation factors is reviewed. Based upon our current understanding of late cardiac effects, a clinical grading system has been developed and is published elsewhere in this issue. 49 refs., 1 tab.

Stewart, J.R. [Univ. of Utah Medical Center, Salt Lake City, UT (United States)] [Univ. of Utah Medical Center, Salt Lake City, UT (United States); Fajardo, L.F. [Stanford Univ. School of Medicine, Palo Alto, CA (United States)] Gillette, S. M. [Colorado State Univ., Fort Collins, CO (United States)] [and others

1995-03-30T23:59:59.000Z

442

Atmospheric propagation of THz radiation.  

SciTech Connect

In this investigation, we conduct a literature study of the best experimental and theoretical data available for thin and thick atmospheres on THz radiation propagation from 0.1 to 10 THz. We determined that for thick atmospheres no data exists beyond 450 GHz. For thin atmospheres data exists from 0.35 to 1.2 THz. We were successful in using FASE code with the HITRAN database to simulate the THz transmission spectrum for Mauna Kea from 0.1 to 2 THz. Lastly, we successfully measured the THz transmission spectra of laboratory atmospheres at relative humidities of 18 and 27%. In general, we found that an increase in the water content of the atmosphere led to a decrease in the THz transmission. We identified two potential windows in an Albuquerque atmosphere for THz propagation which were the regions from 1.2 to 1.4 THz and 1.4 to 1.6 THz.

Wanke, Michael Clement; Mangan, Michael A.; Foltynowicz, Robert J.

2005-11-01T23:59:59.000Z

443

Radiative muon capture in hydrogen  

Science Journals Connector (OSTI)

We analyze the radiative capture of the negative muon in hydrogen using amplitudes derived within the chiral Lagrangian approach. Besides the leading and next to leading order terms, given by the well-known Rood-Tolhoek Hamiltonian, we extract from these amplitudes the corrections of the next order in 1/M (M is the nucleon mass). In addition, we estimate within the same formalism also the ?(1232) isobar excitation effects and processes described by an anomalous Lagrangian. The model we consider allows us to put the ? isobar off-shell. Our calculations show sensitivity of capture rates and photon spectra to Z, one of the off-shell parameters, related to the ?N? vertex. We have found that the model can provide the photon spectra, which are in the interval 60?MeV<~k<~kmax (k is the photon momentum) close to the experimental one.

E. Truhlík and F. C. Khanna

2002-04-01T23:59:59.000Z

444

Radiation Modeling In Fluid Flow Iain D. Boyd  

E-Print Network (OSTI)

Collector #12;4 Fundamentals of Radiation (1) � All matter with non-zero temperature emits thermal radiation with energy flux given by the Stefan-Boltzmann Law: e.g., Sun: T=5800 K, total radiated power = 4 distribution (Planck spectrum) !q =T 4 W/m2 #12;5 Planck Radiation Spectrum #12;6 Solar Radiation Spectrum

Wang, Wei

445

Appendix E. Radiation Annual Site Environmental Report--2011  

E-Print Network (OSTI)

and biological systems. Radiation comes from natural and human-made sources. People are exposed to naturally occurring radiation constantly. For example, cosmic radiation; radon in air; potassium in food and waterAppendix E. Radiation #12;#12;Annual Site Environmental Report--2011 Appendix E. Radiation E-3

Pennycook, Steve

446

Impurity radiation from a tokamak plasma  

SciTech Connect

In tokamak operating modes, energy balance is often governed by impurity radiation. This is the case near the divertor plates, during impurity pellet injection, during controlled discharge disruptions, etc. The calculation of impurity radiation is a fairly involved task (it is sometimes the most difficult part of the general problem) because the radiation power is determined by the distribution of ions over the excited states and by the rate constants of elementary processes of radiation and absorption. The objective of this paper is to summarize in one place all the approximate formulas that would help investigators to describe radiation from the most often encountered impurities in a fairly simple way in their calculations accounting for plasma radiation, without reference to special literature. Simple approximating formulas describing ionization, recombination, and charge-exchange processes, as well as radiative losses from ions with a given charge, are presented for five impurity species: beryllium, carbon, oxygen, neon, and argon. Estimating formulas that allow one to take into account plasma opacity for resonant photons in line impurity radiation are also presented.

Morozov, D. Kh.; Baronova, E. O. [Russian Research Centre Kurchatov Institute, Nuclear Fusion Institute (Russian Federation); Senichenkov, I. Yu. [St. Petersburg State Polytechnical University (Russian Federation)

2007-11-15T23:59:59.000Z

447

Ris National Laboratory Radiation Research Department  

E-Print Network (OSTI)

Risø National Laboratory Postprint Radiation Research Department Year 2007 Paper: www Radiation Physics, Lund University Hospital, 22185 Lund, Sweden 12 Lab. d'Analyses de Surveillance et d Tokai works, Tokai-mura, Naka-gun, Ibaraki 319-1994, Japan 17 Risoe National Laboratory, 4000 Roskilde

448

JOSA COMMUNICATIONS Terahertz radiation from magnetoresistive  

E-Print Network (OSTI)

JOSA COMMUNICATIONS Terahertz radiation from magnetoresistive Pr0.7Ca0.3MnO3 thin films under University, 2-6 Yamadaoka, Suita, Osaka 565-0871, Japan Received April 11, 2005; revised July 17, 2005; accepted July 30, 2005 Terahertz (THz) radiation characteristics have been investigated for voltage

Tonouchi, Masayoshi

449

Helical Undulator Radiation(LCC-0095)  

SciTech Connect

Expressions for the energy spectrum, photon number spectrum, and polarization of radiation emitted from a helical undulator are presented. Photon number normalization is discussed. The effect of angular collimation of the radiation is shown. Matlab script files used in the calculations are listed. Algorithms of what is actually calculated are documented.

Sheppard, J

2003-10-07T23:59:59.000Z

450

How hot is radiation? Christopher Essexa)  

E-Print Network (OSTI)

. Thus radiation is a natural context in which to introduce nonequilibrium temperature. A properly as they exchange a heat flux JQ(12). Subsystem temperatures occur naturally in expres- sions for entropy productionHow hot is radiation? Christopher Essexa) Department of Applied Mathematics, University of Western

Berry, R. Stephen

451

Natural radiation environment III. [Lead Abstract  

SciTech Connect

Separate abstracts were prepared for the 52 research papers presented at this symposium in April 1978. The major topics in this volume deal with penetrating radiation measurements, radiation surveys and population exposure, radioactivity in the indoor environment, and technologically enhanced natural radioactivity. (KRM)

Gesell, T.F.; Lowder, W.M. (eds.)

1980-01-01T23:59:59.000Z

452

The Earth Radiation Budget Experiment (ERBE)  

Science Journals Connector (OSTI)

The Earth Radiation Budget Experiment (ERBE) is the first multi-satellite system designed to measure the Earth's radiation budget. It will fly on a low-inclination NASA satellite and two Sun-synchronous NOAA satellites during the mid-1980s. Each ...

Bruce R. Barkstrom

1984-11-01T23:59:59.000Z

453

College of Medicine RM Radiation Medicine  

E-Print Network (OSTI)

processes; selected nuclear reactions; basic radiation detection and dosimetry. Prereq: PHY 213 or 232; MA, and nuclear medical physics. Prereq or concur: RM/PHY 472G or consent of instructor. (Same as PHY/RAS 546.) RM 601 ADVANCED RADIATION DOSIMETRY. (2

MacAdam, Keith

454

Earth-Moon-Mars Radiation Environment Model  

E-Print Network (OSTI)

successful at predicting SEP spectra and radiation dose estimates at different distances in the inner-dependent estimates of organ dose and dose equivalent rates for human crews in deep space from the 26 Oct 2003 solar orbit, Spaceweather, 8, 2010 · Dayeh, et al, Modeling proton intensity gradients and radiation dose

Pringle, James "Jamie"

455

Estimated Ultraviolet Radiation Doses in Wetlands in  

E-Print Network (OSTI)

Estimated Ultraviolet Radiation Doses in Wetlands in Six National Parks Stephen A. Diamond,1 ABSTRACT Ultraviolet-B radiation (UV-B, 280­320-nm wave- lengths) doses were estimated for 1024 wetlands of vegetative features, and quantification of DOC concentration and spectral absorbance. UV-B dose estimates

Knapp, Roland

456

Low Dose Radiation Research Program: Earlier Events  

NLE Websites -- All DOE Office Websites (Extended Search)

Earlier Events Earlier Events 2000 | 2001 | 2002 | 2003 | 2004 April 2000 Ionizing Radiation Science and Protection in the 21st Century, NCRP, April 5-6, Arlington, VA. RADIATION RESEARCH 2000, Association for Radiation Research, April 10-12, Bristol, UK. Florida Chapter of the Health Physics Society Spring 2000 Meeting, Gainesville, FL, April 13-14. 47th Annual Meeting of the Radiation Research Society, April 29-May 3, Albuquerque, NM. May 2000 IRPA-10 International Congress 2000, May 14-19, Hiroshima, Japan. IRPA-10 Secretariat, c/o Japan Convention Services, Inc., Nippon Press Center Building, 2-2-1, Uchisaiwai-cho, Chiyoda-ku, Tokyo 100, Japan. Phone: 81-3-3508-1214. Fax: 81-3-3508-0820. irpa10@convention.jp. 4th International Non-Ionizing Radiation Workshop, May 22-25, Kyoto,

457

Low Dose Radiation Research Program: Research Institutions  

NLE Websites -- All DOE Office Websites (Extended Search)

Institutions Institutions Lovelace Respiratory Research Institute Biological Bases for Radiation Adaptive Responses in the Lung-Lovelace Respiratory Research Institute, Albuquerque, NM USA Contact: Dr. Bobby R. Scott Program Objective Our research focuses on elucidating the biological bases for radiation adaptive responses in the lung and for suppressing lung cancer, and to use the knowledge gained to produce an improved systems-biology-based, risk model for lung cancer induction by low-dose, low linear-energy-transfer (LET) radiation. Research was initiated in October 2009. This research should help foster a new era of low-dose radiation risk/benefit assessment. It will have important implications for possible use of low-dose diagnostic radiation (e.g., X-rays) in cancer therapy. It

458

Radiation Safety Policy and Procedures Committee  

NLE Websites -- All DOE Office Websites (Extended Search)

RSPPC Meeting Minutes APS only RSPPC Meeting Minutes APS only Radiation Safety Policy and Procedures Committee Charter 1. Purpose The committee reviews functional changes to the Access Control Interlock System (ACIS) and Personnel Protection System (PSS) used to provide personnel protection and area exclusion related to APS accelerators, storage ring and other radiation handling areas. The RSPP Committee advises APS management on radiation safety matters. At the request of APS Management the committee reviews projects, recommends radiation safety policy, and evaluates accident investigation conclusions. 2. Membership Members are appointed by the APS Division Directors and APS Director for their knowledge and background in Interlock Systems, Radiation Safety, Accelerator Operations and Work on the Experiment Floor.

459

National Solar Radiation Database | Open Energy Information  

Open Energy Info (EERE)

National Solar Radiation Database National Solar Radiation Database Jump to: navigation, search The National Solar Radiation Database, or NSRDB, describes the amount of solar energy which is available at any location in the United States. It is generated by the National Renewable Energy Laboratory, with the assistance of many collaborators.[1] Technical Overview Per its user's manual, "The NSRDB is a serially complete collection of hourly values of the three most common measurements of solar radiation (global horizontal, direct normal, and diffuse horizontal) over a period of time adequate to establish means and extremes, and at a sufficient number of locations to represent regional solar radiation climates."[2] There have been two releases of the NSRDB, each covering different time

460

Radiative Heat Transfer between Neighboring Particles  

E-Print Network (OSTI)

The near-field interaction between two neighboring particles is known to produce enhanced radiative heat transfer. We advance in the understanding of this phenomenon by including the full electromagnetic particle response, heat exchange with the environment, and important radiative corrections both in the distance dependence of the fields and in the particle absorption coefficients. We find that crossed terms of electric and magnetic interactions dominate the transfer rate between gold and SiC particles, whereas radiative corrections reduce it by several orders of magnitude even at small separations. Radiation away from the dimer can be strongly suppressed or enhanced at low and high temperatures, respectively. These effects must be taken into account for an accurate description of radiative heat transfer in nanostructured environments.

Alejandro Manjavacas; F. Javier Garcia de Abajo

2012-01-26T23:59:59.000Z

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461

Initial conditions of radiative shock experiments  

SciTech Connect

We performed experiments at the Omega Laser Facility to characterize the initial, laser-driven state of a radiative shock experiment. These experiments aimed to measure the shock breakout time from a thin, laser-irradiated Be disk. The data are then used to inform a range of valid model parameters, such as electron flux limiter and polytropic ?, used when simulating radiative shock experiments using radiation hydrodynamics codes. The characterization experiment and the radiative shock experiment use a laser irradiance of ?7 × 10{sup 14} W cm{sup ?2} to launch a shock in the Be disk. A velocity interferometer and a streaked optical pyrometer were used to infer the amount of time for the shock to move through the Be disk. The experimental results were compared with simulation results from the Hyades code, which can be used to model the initial conditions of a radiative shock system using the CRASH code.

Kuranz, C. C.; Drake, R. P.; Krauland, C. M.; Marion, D. C.; Grosskopf, M. J.; Rutter, E.; Torralva, B.; Holloway, J. P. [Department of Atmospheric, Oceanic and Space Science, University of Michigan, Center for Radiative Shock Hydrodynamics, 2455 Hayward Dr., Ann Arbor, Michigan 48109 (United States)] [Department of Atmospheric, Oceanic and Space Science, University of Michigan, Center for Radiative Shock Hydrodynamics, 2455 Hayward Dr., Ann Arbor, Michigan 48109 (United States); Bingham, D.; Goh, J. [Department of Statistics and Actuarial Science, Simon Fraser University, Burnaby, BC, Canada V5A 1S6 (Canada)] [Department of Statistics and Actuarial Science, Simon Fraser University, Burnaby, BC, Canada V5A 1S6 (Canada); Boehly, T. R.; Sorce, A. T. [Laboratory for Laser Energetics, University of Rochester, New York 14623 (United States)] [Laboratory for Laser Energetics, University of Rochester, New York 14623 (United States)

2013-05-15T23:59:59.000Z

462

On the Classical Radiation of Accelerated Electrons  

Science Journals Connector (OSTI)

This paper is concerned with the properties of the radiation from a high energy accelerated electron, as recently observed in the General Electric synchrotron. An elementary derivation of the total rate of radiation is first presented, based on Larmor's formula for a slowly moving electron, and arguments of relativistic invariance. We then construct an expression for the instantaneous power radiated by an electron moving along an arbitrary, prescribed path. By casting this result into various forms, one obtains the angular distribution, the spectral distribution, or the combined angular and spectral distributions of the radiation. The method is based on an examination of the rate at which the electron irreversibly transfers energy to the electromagnetic field, as determined by half the difference of retarded and advanced electric field intensities. Formulas are obtained for an arbitrary charge-current distribution and then specialized to a point charge. The total radiated power and its angular distribution are obtained for an arbitrary trajectory. It is found that the direction of motion is a strongly preferred direction of emission at high energies. The spectral distribution of the radiation depends upon the detailed motion over a time interval large compared to the period of the radiation. However, the narrow cone of radiation generated by an energetic electron indicates that only a small part of the trajectory is effective in producing radiation observed in a given direction, which also implies that very high frequencies are emitted. Accordingly, we evaluate the spectral and angular distributions of the high frequency radiation by an energetic electron, in their dependence upon the parameters characterizing the instantaneous orbit. The average spectral distribution, as observed in the synchrotron measurements, is obtained by averaging the electron energy over an acceleration cycle. The entire spectrum emitted by an electron moving with constant speed in a circular path is also discussed. Finally, it is observed that quantum effects will modify the classical results here obtained only at extraordinarily large energies.

Julian Schwinger

1949-06-15T23:59:59.000Z

463

E-Print Network 3.0 - assessing radiation dose Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

of radiation; radiation measurement; and dose information. ATOMS... Assessments, DOETIC-11026. RADIATION Radiation, or radiant energy, is energy in the form of waves... )...

464

Solar UV radiation reduces the barrier function of human skin  

Science Journals Connector (OSTI)

Solar UV radiation reduces the barrier function...Stanford, CA 94305 The ubiquitous presence of solar UV radiation in human life is essential for...defense against environmental exposures like solar UV radiation, and its effects on UV targets...

Krysta Biniek; Kemal Levi; Reinhold H. Dauskardt

2012-01-01T23:59:59.000Z

465

Occupational radiation monitoring at a large medical center in Japan  

Science Journals Connector (OSTI)

Occupational radiation dose monitoring is a method of ensuring that radiation levels are within the regulatory limits. Our objective in this study was to evaluate the radiation doses experienced by personnel ...

Hussein Y. ALMasri; Yasumasa Kakinohana…

2014-07-01T23:59:59.000Z

466

Radiation safety and quality control in the cyclotron laboratory  

Science Journals Connector (OSTI)

......and Technical Papers Radiation safety and quality control...Forks, ND 58203, USA Radiation safety was determined to...to save SCADA node software and avoid run failure...prove compliance with radiation safety standards, and minimise......

Sushil Sharma; Gregory Krause; Manuchair Ebadi

2006-07-01T23:59:59.000Z

467

IEC standards for individual monitoring of ionising radiation  

Science Journals Connector (OSTI)

......rate) quantities and radiation: H p(10) and H p...general test procedures, radiation characteristics as well...electrical, mechanical, safety and environmental characteristics...performance requirements, radiation characteristics as well...electrical, mechanical and software characteristics. The......

M. Voytchev; P. Ambrosi; R. Behrens; P. Chiaro

2011-03-01T23:59:59.000Z

468

Lessons from recent accidents in radiation therapy in France  

Science Journals Connector (OSTI)

......relative to the use of ionising radiation including medical applications...irsn.fr | Journal Article | Brain radiation effects surgery France Head and...control Radiometry Radiotherapy Safety Scattering, Radiation Software...

S. Derreumaux; C. Etard; C. Huet; F. Trompier; I. Clairand; J.-F. Bottollier-Depois; B. Aubert; P. Gourmelon

2008-08-01T23:59:59.000Z

469

The Degradation of Solid Polymethylmethacrylate by Ionizing Radiation  

Science Journals Connector (OSTI)

...Polymethylmethacrylate by Ionizing Radiation P. Alexander A. Charlesby...inversely proportional to the radiation dose (plus a small quantity of...of measuring high-energy radiation doses in the range of about 1 million rontgens...

1954-01-01T23:59:59.000Z

470

Ionizing Radiation Activates the Nrf2 Antioxidant Response  

Science Journals Connector (OSTI)

...Scientific). Results Ionizing radiation does not activate ARE-reporter...determine if exposure to varying doses of ionizing radiation would activate the Nrf2-ARE pathway. The radiation dose range was extended below that used...

J. Tyson McDonald; Kwanghee Kim; Andrew J. Norris; Erina Vlashi; Tiffany M. Phillips; Chann Lagadec; Lorenza Della Donna; Josephine Ratikan; Heather Szelag; Lynn Hlatky; and William H. McBride

2010-11-01T23:59:59.000Z

471

Ionizing Radiation Induces Delayed Hyperrecombination in Mammalian Cells  

Science Journals Connector (OSTI)

...instability is critical to radiation risk assessment and for determining...the many delayed effects of radiation, chromosomal instability is...detrimental effects over a range of doses of ionizing radiation. Furthermore, a rapid and...

Lei Huang; Suzanne Grim; Leslie E. Smith; Perry M. Kim; Jac A. Nickoloff; Olga G. Goloubeva; William F. Morgan

2004-06-01T23:59:59.000Z

472

Solar radiation induces sublethal injury in Escherichia coli in seawater.  

Science Journals Connector (OSTI)

...after cells were exposed to solar radiation. Injury was detected...030670-05$02.00/0 Solar Radiation Induces Sublethal...Harvard University, Cambridge, Massachusetts 02138 Sublethal injury was...after cells were exposed to solar radiation. Injury was detected...

R B Kapuscinski; R Mitchell

1981-03-01T23:59:59.000Z

473

Multilevel bioluminescence tomography based on radiative transfer equation  

E-Print Network (OSTI)

, "A fast forward solver of radiative transfer equation," Transport Theory and Statistical Physics 38Multilevel bioluminescence tomography based on radiative transfer equation Part 1: l1 approach for bioluminescence tomography based on radiative transfer equation with the emphasis on improving

Soatto, Stefano

474

IONIZING RADIATION RISKS TO SATELLITE POWER SYSTEMS (SPS) WORKERS  

E-Print Network (OSTI)

Dose-Response Relationships for Radiation-Induced Cancer EstimationDose-Response Relationships for Radiation-Induced Cancer A general hypothesis for estimationof the total dose. Estimation of Space Radiation Induced

Lyman, J.T.

2010-01-01T23:59:59.000Z

475

Paper replication method for isolation of radiation-sensitive mutants.  

Science Journals Connector (OSTI)

...homogeneous with regard to radiation resistance. This, in turn...from each colony contacted. Radiation as the discriminating agent for sensi- tive RCs. An estimation of the proper radiation dose was obtained from the results...

S T Tan; R B Maxcy; T L Thompson

1983-07-01T23:59:59.000Z

476

RADIATIVE HEATING OF THE SOLAR CORONA  

SciTech Connect

We investigate the effect of solar visible and infrared radiation on electrons in the Sun's atmosphere using a Monte Carlo simulation of the wave-particle interaction and conclude that sunlight provides at least 40% and possibly all of the power required to heat the corona, with the exception of dense magnetic flux loops. The simulation uses a radiation waveform comprising 100 frequency components spanning the solar blackbody spectrum. Coronal electrons are heated in a stochastic manner by low coherence solar electromagnetic radiation. The wave 'coherence time' and 'coherence volume' for each component is determined from optical theory. The low coherence of solar radiation allows moving electrons to gain energy from the chaotic wave field which imparts multiple random velocity 'kicks' to these particles causing their velocity distribution to broaden or heat. Monte Carlo simulations of broadband solar radiative heating on ensembles of 1000 electrons show heating at per particle levels of 4.0 x 10{sup -21} to 4.0 x 10{sup -20} W, as compared with non-loop radiative loss rates of {approx}1 x 10{sup -20} W per electron. Since radiative losses comprise nearly all of the power losses in the corona, sunlight alone can explain the elevated temperatures in this region. The volume electron heating rate is proportional to density, and protons are assumed to be heated either by plasma waves or through collisions with electrons.

Moran, Thomas G., E-mail: moran@grace.nascom.nasa.gov [Physics Department, Catholic University of America, 200 Hannan Hall, Washington, DC 20064 (United States) and NASA/GSFC, Code 671, Greenbelt, MD 20771 (United States)

2011-10-20T23:59:59.000Z

477

Properties of Natural Radiation and Radioactivity  

SciTech Connect

Ubiquitous natural sources of radiation and radioactive material (naturally occurring radioactive material, NORM) have exposed humans throughout history. To these natural sources have been added technologically-enhanced naturally occurring radioactive material (TENORM) sources and human-made (anthropogenic) sources. This chapter describes the ubiquitous radiation sources that we call background, including primordial radionuclides such as 40K, 87Rb, the 232Th series, the 238U series, and the 235U series; cosmogenic radionuclides such as 3H and 14C; anthropogenic radionuclides such as 3H, 14C, 137Cs, 90Sr, and 129I; radiation from space; and radiation from technologically-enhanced concentrations of natural radionuclides, particularly the short-lived decay products of 222Rn ("radon") and 220Rn ("thoron") in indoor air. These sources produce radiation doses to people principally via external irradiation or internal irradiation following intakes by inhalation or ingestion. The effective doses from each are given, with a total of 3.11 mSv y-1 (311 mrem y-1) to the average US resident. Over 2.5 million US residents receive over 20 mSv y-1 (2 rem y-1), primarily due to indoor radon. Exposure to radiation from NORM and TENORM produces the largest fraction of ubiquitous background exposure to US residents, on the order of 2.78 mSv (278 mrem) or about 89%. This is roughly 45% of the average annual effective dose to a US resident of 6.2 mSv y-1 (620 mrem y-1) that includes medical (48%), consumer products and air travel (2%), and occupational and industrial (0.1%). Much of this chapter is based on National Council on Radiation Protection and Measurements (NCRP) Report No. 160, "Ionizing Radiation Exposure of the Population of the United States," for which the author chaired the subcommittee that wrote Chapter 3 on "Ubiquitous Background Radiation."

Strom, Daniel J.

2009-07-13T23:59:59.000Z

478

Estimating Radiation Risk from Total Effective Dose Equivalent...  

National Nuclear Security Administration (NNSA)

and UNSCEAR 1988 in Radiation Risk Assessment - Lifetime Total Cancer Mortality Risk Estimates at Low Doses and Low Dose Rates for Low-LET Radiation, Committee on Interagency...

479

Laser Seeding Yields High-Power Coherent Terahertz Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Laser Seeding Yields High-Power Coherent Terahertz Radiation Laser Seeding Yields High-Power Coherent Terahertz Radiation Print Wednesday, 25 April 2007 00:00 Researchers at...

480

Laser Seeding Yields High-Power Coherent Terahertz Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Laser Seeding Yields High-Power Coherent Terahertz Radiation Print Researchers at Berkeley Lab have been exploring the ways coherent synchrotron radiation (CSR) is generated in...