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1

Molecular Mechanism Underlying Cellular Adaptive Response to Low Dose Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Mechanism Underlying Cellular Adaptive Response to Low Dose Radiation Mechanism Underlying Cellular Adaptive Response to Low Dose Radiation Colette A. Sacksteder § , DJ Black ‡ , Heather Smallwood § , David G. Camp II † , and Thomas C. Squier § § Cell Biology and Biochemistry; † Biological Sciences Division Pacific Northwest National Laboratory, Richland WA 99352 ‡ School of Biological Sciences, University of Missouri, Kansas City MO 64110 The goal of this research is to identify the molecular mechanisms by which cells adapt to low dose radiation exposure. Previously we have shown a radiation dependent increase of Calmodulin (CaM) in RAW 264.7 macrophages (RAW). Therefore we hypothesize that CaM and associated signaling complexes are sensors of low-dose radiation, resulting in alterations in energy metabolism and gene expression. The ultimate experimental goal

2

Biological Basis for Radiation Adaptive Responses that Protect Against  

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Basis for Radiation Adaptive Responses that Protect Against Basis for Radiation Adaptive Responses that Protect Against Bronchial Epithelial Cell Transformation Wenshu Chen Lovelace Respiratory Research Institute Abstract The major hypothesis in this project is that low-dose, low linear-energy-transfer (LET) radiation stimulates an adaptive response that protects cells from neoplastic transformation involving modulation of paracrine factors (e.g., cytokines), cell survival/death signaling pathways, and reprogramming of the epigenome. To test this hypothesis, a validated, sensitive in vitro transformation model and a media transfer method were used to study the mechanisms of low-LET gamma radiation activated natural protection (ANP) against chemical carcinogen-induced bronchial cell transformation. Immortalized human bronchial epithelial cell

3

Low Dose Radiation Research Program: Adaptive Response of Mouse Skin  

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Adaptive Response of Mouse Skin Epithelial Cells to Low Dose Adaptive Response of Mouse Skin Epithelial Cells to Low Dose Ionizing Radiation: Induction of NF-κB, MnSOD, 14-3-3ζ and Cyclin B1 Authors: Jian Jian Li, Kazi M. Ahmed, Ming Fan, Shaozhong Dong, Douglas R. Spitz, and Cheng-Rong Yu Institutions: Division of Molecular Radiobiology, Purdue University School of Health Sciences, West Lafayette, Indiana; Free Radical and Radiation Biology Program, Department of Radiation Oncology, Holden Comprehensive Cancer Center, The University of Iowa, Iowa City, Iowa; Molecular Immunology Section, Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland Gene expression profiles demonstrate that a group of key stress-responsive genes are associated with radiation exposure and may contribute to cellular

4

Biological Basis for Radiation Adaptive Responses that Protect Against Bronchial Epithelial Cell Transformation  

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Basis for Radiation Adaptive Responses that Protect Against Bronchial Basis for Radiation Adaptive Responses that Protect Against Bronchial Epithelial Cell Transformation Wenshu Chen, Xiuling Xu, Lang Bai, Mabel T. Padilla, Carmen Tellez, Katherine M. Gott, Shuguang Leng, Julie A. Wilder, Steven A. Belinsky, Bobby R. Scott and Yong Lin, Lovelace Respiratory Research Institute, 2425 Ridgecrest Drive SE, Albuquerque, NM 87108 The major hypothesis in this project is that low-dose, low linear-energy-transfer (LET) radiation stimulates an adaptive response that protects cells from neoplastic transformation involving modulation of paracrine factors (e.g., cytokines), cell survival/death signaling pathways, and reprogramming of the epigenome. To test this hypothesis, a validated, sensitive in vitro transformation model and a media transfer

5

{sub p}53-Dependent Adaptive Responses in Human Cells Exposed to Space Radiations  

SciTech Connect

Purpose: It has been reported that priming irradiation or conditioning irradiation with a low dose of X-rays in the range of 0.02-0.1 Gy induces a p53-dependent adaptive response in mammalian cells. The aim of the present study was to clarify the effect of space radiations on the adaptive response. Methods and Materials: Two human lymphoblastoid cell lines were used; one cell line bears a wild-type p53 (wtp53) gene, and another cell line bears a mutated p53 (mp53) gene. The cells were frozen during transportation on the space shuttle and while in orbit in the International Space Station freezer for 133 days between November 15, 2008 and March 29, 2009. After the frozen samples were returned to Earth, the cells were cultured for 6 h and then exposed to a challenging X-ray-irradiation (2 Gy). Cellular sensitivity, apoptosis, and chromosome aberrations were scored using dye-exclusion assays, Hoechst33342 staining assays, and chromosomal banding techniques, respectively. Results: In cells exposed to space radiations, adaptive responses such as the induction of radioresistance and the depression of radiation-induced apoptosis and chromosome aberrations were observed in wtp53 cells but not in mp53 cells. Conclusion: These results have confirmed the hypothesis that p53-dependent adaptive responses are apparently induced by space radiations within a specific range of low doses. The cells exhibited this effect owing to space radiations exposure, even though the doses in space were very low.

Takahashi, Akihisa [Department of Biology, School of Medicine, Nara Medical University, Nara (Japan); Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency, Ibaraki (Japan); Su Xiaoming [Department of Biology, School of Medicine, Nara Medical University, Nara (Japan); Suzuki, Hiromi [Japan Space Forum, Tokyo (Japan); Space Environmental Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima (Japan); Omori, Katsunori [Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency, Ibaraki (Japan); Seki, Masaya; Hashizume, Toko [Space Environmental Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima (Japan); Advanced Engineering Services Company, Limited, Ibaraki (Japan); Shimazu, Toru [Japan Space Forum, Tokyo (Japan); Ishioka, Noriaki [Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency, Ibaraki (Japan); Space Environmental Medicine, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima (Japan); Iwasaki, Toshiyasu [Radiation Safety Research Center, Nuclear Technology Research Laboratory, Central Research Institute of the Electric Power Industry of Japan, Tokyo (Japan); Ohnishi, Takeo, E-mail: tohnishi@naramed-u.ac.j [Department of Radiation Oncology, School of Medicine, Nara Medical University, Nara (Japan); Institute of Space and Astronautical Science, Japan Aerospace Exploration Agency, Ibaraki (Japan)

2010-11-15T23:59:59.000Z

6

Adaptive Response Against Spontaneous Neoplastic Transformation In Vitro Induced by Ionizing Radiation  

SciTech Connect

The goal of this project was to establish a dose response curve for radiation-induced neoplastic transformation of HeLa x skin fibroblast human hybrid cells in vitro under experimental conditions were an adaptive response, if it were induced, would have an opportunity to be expressed. During the first two years of the grant an exhaustive series of experiments were performed and the resulting data were reported at the 2000 Annual Meeting of the Radiation Research Society and then Subsequently published. The data showed that an adaptive response against spontaneous neoplastic transformation was seen up to doses of 10cGy of Cs-137 gamma rays. At dose of 30, 50 and 100 cGy the transformation frequencies were above background. This indicated that for this system, under the specific experimental conditions used, there was a threshold of somewhere between 10 and 30 cGy. The results also indicated some unexpected, though very interesting, correlations with relative risk estimates made from human epidemiologic studies.

J. Leslie Redpath, Ph.D.

2003-11-10T23:59:59.000Z

7

Radiation-induced bystander effect and adaptive response in mammalian cells  

E-Print Network (OSTI)

responses at low doses of radiation and have the potential to impact the shape of the dose the actual target and radiation dose effect and can contribute to our current understanding in radiation risk provide the best estimate of cancer risk over the dose range from 20 to 250 cGy. The cancer risk at doses

8

Molecular Mechanisms Involved in Adaptive Responses to Radiation, UV light, and Heat  

Science Journals Connector (OSTI)

......B. (2002) The role of UV-B radiation in aquatic and terrestrial ecosystems-an experimental and functional analysis of...Takahashi, A. and Okaichi, K. (1999) Restoration of mutant TP53 to normal TP53 function by glycerol......

Akihisa Takahashi; Takeo Ohnishi

2009-09-01T23:59:59.000Z

9

7, 72357275, 2007 Adaptive radiative  

E-Print Network (OSTI)

Discussions Two adaptive radiative transfer schemes for numerical weather prediction models V. Venema 1 , A numerical weather prediction (NWP) and climate models. The atmosphere and the land surface are complex-stream approximation. In most weather prediction models these parameterisation schemes are therefore called infre

Boyer, Edmond

10

Study Shows Roles of Receptor, Thiol on Adaptive Response  

NLE Websites -- All DOE Office Websites (Extended Search)

Study Shows Roles of Receptor, Thiol on Adaptive Response Study Shows Roles of Receptor, Thiol on Adaptive Response Jeffrey Murley Jeffrey Murley, Ph.D. David Grdina, Ph.D. Low Dose program-supported scientists at The University of Chicago have gained more insight into adaptive protective responses indicating the role of oxidative stress, the role of reactive oxygen species (ROS), and the induction of SOD2 (manganese Superoxide Dismutase) activity. These changes are central to the production of adaptive protective responses. Why Study Adaptive Response? Exposing cells to low doses of ionizing radiation has been reported to elevate resistance to genomic damage when the same cells are subsequently exposed to a much higher dose of radiation. This phenomenon, called adaptive response, is characterized by an increase

11

A Critical Examination of the Adaptive Response for Cytogenetic Damagein Human Cells, and Insights into the Adaptive Response Mechanism  

NLE Websites -- All DOE Office Websites (Extended Search)

Critical Examination of the Adaptive Response for Cytogenetic Damage Critical Examination of the Adaptive Response for Cytogenetic Damage in Human Cells, and Insights into the Adaptive Response Mechanism Björn E. Rydberg, Torsten Groesser, Antoine Snijders, Kelly Trego, Ju Han, Do Yup Lee, Bahram Parvin, Trent Northen, Andrew J. Wyrobek, and Priscilla K. Cooper Berkeley Lab SFA P.I.: Gary Karpen Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720 Goal: Task 1 of the Berkeley Lab SFA is designed to identify adaptive response (AR) mechanisms that may affect risk of developing radiation-induced cancer and to assess the linearity with dose of processes that influence mammary gland carcinogenesis. We use both in vitro and in vivo experimental systems in a parallelogram strategy. Our human cell culture

12

Adaptive radiation of chemosymbiotic deep-sea mussels  

Science Journals Connector (OSTI)

...are credited. Adaptive radiation of chemosymbiotic deep-sea...Research Department, Japan Agency for Marine-Earth...Yokosuka 237-0061, Japan 2 Geoscience Center...Yamanashi 400-8510, Japan Adaptive radiations present fascinating opportunities...

2013-01-01T23:59:59.000Z

13

E-Print Network 3.0 - adaptive response induced Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

Yin and Yang of Low-Dose Radiobiology Tom K. Hei1,2 Summary: and adaptive response. Radiation-induced bystander effect is defined as the induction of biological effects... the...

14

E-Print Network 3.0 - adaptive responses induced Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

Yin and Yang of Low-Dose Radiobiology Tom K. Hei1,2 Summary: and adaptive response. Radiation-induced bystander effect is defined as the induction of biological effects... the...

15

Low Dose Responses in Human Cells and Molecular Mechanisms of Adaptation  

NLE Websites -- All DOE Office Websites (Extended Search)

Responses in Human Cells and Molecular Mechanisms of Adaptation Responses in Human Cells and Molecular Mechanisms of Adaptation Joe Gray Priscilla Cooper Lawrence Berkeley National Laboratory Abstract The radiation Adaptive Response (adaptation, or AR) is a well documented, although evidently highly variable, protective phenomenon in which exposures to low-dose or low-dose-rate ionizing radiation result in reduced deleterious effects of subsequent higher exposures. Protection has been reported against a variety of biologically important endpoints, but its variability as a function of cell and tissue type and its genetic control are not well understood. The adaptive response is predicted to result in a non-linear dose response for cancer risk in the low dose range. However, the molecular mechanism(s) remain unknown, and such information is

16

Verifying a nuclear weapon`s response to radiation environments  

SciTech Connect

The process described in the paper is being applied as part of the design verification of a replacement component designed for a nuclear weapon currently in the active stockpile. This process is an adaptation of the process successfully used in nuclear weapon development programs. The verification process concentrates on evaluating system response to radiation environments, verifying system performance during and after exposure to radiation environments, and assessing system survivability.

Dean, F.F.; Barrett, W.H.

1998-05-01T23:59:59.000Z

17

Low Dose Radiation Research Program: Genetic Control of Repair and Adaptive  

NLE Websites -- All DOE Office Websites (Extended Search)

Repair and Adaptive Responses to Low-level DNA Damage Repair and Adaptive Responses to Low-level DNA Damage James E. Haber Brandeis University Why This Project In order to fully understand mechanisms resulting in effects of low dose, whole system rather than cells must be examined. Although not identical to mammalian systems, simple systems usually have many similarities and give direction for further study of more complex systems. We use the budding yeast, Saccharomyces cerevisiae, as a model system because it is easy to manipulate and its genome is simple and well characterized. Project Goals Examine mechanisms and effects of low dose radiation response for: Genetic recombination mechanisms that lead to genomic instability Genetic factors that affect individual susceptibility to low-dose radiation The adaptive response

18

A Critical Examination of the Adaptive Response for Cytogenetic Damage in  

NLE Websites -- All DOE Office Websites (Extended Search)

Critical Examination of the Adaptive Response for Cytogenetic Damage in Critical Examination of the Adaptive Response for Cytogenetic Damage in Human Cells, and Insights into the Adaptive Response Mechanism Björn E. Rydberg Lawrence Berkeley National Laboratory Abstract Goal: Task 1 of the Berkeley Lab SFA is designed to identify adaptive response (AR) mechanisms that may affect risk of developing radiation-induced cancer and to assess the linearity with dose of processes that influence mammary gland carcinogenesis. We use both in vitro and in vivo experimental systems in a parallelogram strategy. Our human cell culture model will elucidate the molecular mechanisms of the AR and investigate the relationships in target vs. non-target cells between a range of cancer-relevant endpoints potentially affected by adaptation such

19

Effects of Radiation on Adaptive Immunity: Contact Hypersensitivity Model  

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Radiation on Adaptive Immunity: Contact Hypersensitivity Model Radiation on Adaptive Immunity: Contact Hypersensitivity Model Gregory Nelson Loma Linda University Abstract It has long been appreciated that cells of the immune system are radiosensitive and use apoptosis as the primary mechanism of cell death following injury. The hypervariability of the immunoglobulin superfamily of genes expressed in lymphoid cells also led to the appreciation of the nonhomologous end joining mechanism of DNA repair. Clinically, whole body irradiation is used in treatment of some lymphomas and as an immunosuppressive agent for bone marrow transplants. Inflammation at sites of radiotherapy is a common side effect. Many studies with radiation have addressed the changes in cell populations following radiation exposure and have shown a reproducible pattern of relative sensitivities amongst

20

Origin, adaptive radiation and diversification of the Hawaiian lobeliads (Asterales: Campanulaceae)  

Science Journals Connector (OSTI)

...Givnish, T.J Adaptive radiation of plants on oceanic islands...Givnish, T.J Adaptive radiation, dispersal, and diversification...Kato1999pp. 67-90. Eds. Tokyo, Japan:Springer. Givnish, T...Molecular evolution and adaptive radiation T.J Givnish and K.J Sytsma1997pp...

2009-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "radiation adaptive responses" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


21

An adaptive crystal bender for high power synchrotron radiation beams  

SciTech Connect

Perfect crystal monochromators cannot diffract x-rays efficiently, nor transmit the high source brightness available at synchrotron radiation facilities, unless surface strains within the beam footprint are maintained within a few arcseconds. Insertion devices at existing synchrotron sources already produce x-ray power density levels that can induce surface slope errors of several arcseconds on silicon monochromator crystals at room temperature, no matter how well the crystal is cooled. The power density levels that will be produced by insertion devices at the third-generation sources will be as much as a factor of 100 higher still. One method of restoring ideal x-ray diffraction behavior, while coping with high power levels, involves adaptive compensation of the induced thermal strain field. The design and performance, using the X25 hybrid wiggler beam line at the National Synchrotron Light Source (NSLS), of a silicon crystal bender constructed for this purpose are described.

Berman, L.E.; Hastings, J.B.

1992-01-01T23:59:59.000Z

22

An adaptive crystal bender for high power synchrotron radiation beams  

SciTech Connect

Perfect crystal monochromators cannot diffract x-rays efficiently, nor transmit the high source brightness available at synchrotron radiation facilities, unless surface strains within the beam footprint are maintained within a few arcseconds. Insertion devices at existing synchrotron sources already produce x-ray power density levels that can induce surface slope errors of several arcseconds on silicon monochromator crystals at room temperature, no matter how well the crystal is cooled. The power density levels that will be produced by insertion devices at the third-generation sources will be as much as a factor of 100 higher still. One method of restoring ideal x-ray diffraction behavior, while coping with high power levels, involves adaptive compensation of the induced thermal strain field. The design and performance, using the X25 hybrid wiggler beam line at the National Synchrotron Light Source (NSLS), of a silicon crystal bender constructed for this purpose are described.

Berman, L.E.; Hastings, J.B.

1992-10-01T23:59:59.000Z

23

E-Print Network 3.0 - adaptive response ar Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

of adaptation could approximate the ARs of P-cells on a single-trial basis in response to a richer stimulus... and color-sensitive pathway) showed response adaptation with...

24

Major adaptive radiation in neritopsine gastropods estimated from 28S rRNA sequences and fossil records  

Science Journals Connector (OSTI)

...2178 Major adaptive radiation in neritopsine gastropods...of Geology Tokyo Japan Chiba Satoshi Author...Tohoku University Japan 2457 2465 PRLBA4...2002 Major adaptive radiation in neritopsine gastropods...Prefecture, Central Japan. Trans. Proc...291324. Adaptive radiation in neritopsine gastropods...

2002-01-01T23:59:59.000Z

25

Global methylation responses to low dose radiation exposure  

NLE Websites -- All DOE Office Websites (Extended Search)

methylation responses to low dose radiation exposure methylation responses to low dose radiation exposure Pamela J Sykes, Michelle R Newman, Benjamin J Blyth and Rebecca J Ormsby Haematology and Genetic Pathology, Flinders University and Medical Centre, Flinders Centre for Cancer Prevention and Control, Bedford Park, Adelaide, South Australia 5042 Australia. (pam.sykes@flinders.edu.au). Our goal is to study the mechanisms involved in biological responses to low doses of radiation in vivo in the dose range that is relevant to population and occupational exposures. At high radiation doses, DNA double-strand breaks are considered the critical lesion underlying the initiation of radiation-induced carcinogenesis. However, at the very low radiation doses relevant for the general public, the induction of DNA double-strand breaks

26

NNSA Transfers Responsibility for Radiation Detection System...  

National Nuclear Security Administration (NNSA)

Twitter, Tumblr, YouTube and Flickr. Established by Congress in 2000, NNSA is a semi-autonomous agency within the U.S. Department of Energy responsible for enhancing national...

27

7th International Workshop on Microbeam Probes of Cellular Radiation Response  

SciTech Connect

The extended abstracts that follow present a summary of the Proceedings of the 7th International Workshop: Microbeam Probes of Cellular Radiation Response, held at Columbia Universitys Kellogg Center in New York City on March 1517, 2006. These International Workshops on Microbeam Probes of Cellular Radiation Response have been held regularly since 1993 (15). Since the first workshop, there has been a rapid growth (see Fig. 1) in the number of centers developing microbeams for radiobiological research, and worldwide there are currently about 30 microbeams in operation or under development. Single-cell/single-particle microbeam systems can deliver beams of different ionizing radiations with a spatial resolution of a few micrometers down to a few tenths of a micrometer. Microbeams can be used to addressquestions relating to the effects of low doses of radiation (a single radiation track traversing a cell or group of cells), to probe subcellular targets (e.g. nucleus or cytoplasm), and to address questions regarding the propagation of information about DNA damage (for example, the radiation-induced bystander effect). Much of the recent research using microbeams has been to study low-dose effects and non-targeted responses such as bystander effects, genomic instability and adaptive responses. This Workshop provided a forum to assess the current state of microbeam technology and current biological applications and to discuss future directions for development, both technological and biological. Over 100 participants reviewed the current state of microbeam research worldwide and reported on new technological developments in the fields of both physics and biology.

Brenner, David J.

2009-07-21T23:59:59.000Z

28

Convergent evolution of behavior in an adaptive radiation of Hawaiian web-building spiders  

E-Print Network (OSTI)

Convergent evolution of behavior in an adaptive radiation of Hawaiian web-building spiders Todd A independently evolve webs with similar architectures. Tetragnatha spiders are the only nocturnal orb- weaving-occur within mesic and wet forest habitats on each of the main islands. Therefore, comparison of web

Blackledge, Todd

29

Adaptive Responses to Low Dose/Low Dose-Rate γ-Rays in Normal Human Fibroblasts:  

NLE Websites -- All DOE Office Websites (Extended Search)

Responses to Low Dose/Low Dose-Rate γ-Rays in Normal Human Fibroblasts: Responses to Low Dose/Low Dose-Rate γ-Rays in Normal Human Fibroblasts: The Role of Oxidative Metabolism Edouard I. Azzam 1 , Sonia M. de Toledo 1 , Badri N. Pandey 1 , Perumal Venkatachalam 1 , Manuela Buoannano 1 , Zhi Yang 1 , Ling Li 3 , Donna M. Gordon 2 , Roger W. Howell 1 , Debkumar Pain 2 and Douglas R. Spitz 3 1 Department of Radiology, 2 Department of Pharmacology and Physiology, UMDNJ-New Jersey Medical School, Newark, NJ 3 Free Radical and Radiation Biology Program, University of Iowa, Iowa City, IA To investigate low dose/low dose-rate effects of low linear energy transfer ionizing radiation, we used γ-irradiated cells adapted to grow in three-dimensional architecture that mimics cell growth in vivo. We determined cellular, molecular and biochemical changes in these

30

Response of structural materials to radiation environments  

SciTech Connect

An evaluation of proton and neutron damage to aluminum, stainless steel, nickel alloys, and various aluminum alloys has been performed. The proton studies were conducted at energies of 200 MeV, 800 MeV, and 23.5 GeV. The proton studies consisted of evaluation and characterization of proton-irradiated window/target materials from accelerators and comparison to nonirradiated archival materials. The materials evaluated for the proton irradiations included 99.9999 wt% aluminum, 1100 aluminum, 5052 aluminum, 304 stainless steel, and inconel 718. The neutron damage research centered on 6061 T-6 aluminum which was obtained from a control-rod follower from the Brookhaven National Laboratory`s (BNL) High Flux Beam Reactor (HFBR). This material had received thermal neutron fluence up to {approximately}4 {times} 10{sup 23} n/cm{sup 2}. The possible effects of thermal-to-fast neutron flux ratios are discussed. The increases in tensile strength in the proton-irradiated materials is shown to be the result of atomic displacements. These displacements cause interstitials and vacancies which aggregate into defect clusters which result in radiation hardening of the materials. Production of gas (helium) in the grain boundaries of proton irradiated 99.9999 wt% aluminum is also discussed. The major factor contributing to the mechanical-property changes in the neutron-irradiated 6061 T-6 aluminum is the production of transmutation products formed by interactions of the aluminum with thermal neutrons. The metallurgical and mechanical-property evaluations for the research consisted of electron microscopy (both scanning and transmission), tensile testing, and microhardness testing.

Czajkowski, C.J.

1997-12-01T23:59:59.000Z

31

CRASH: A BLOCK-ADAPTIVE-MESH CODE FOR RADIATIVE SHOCK HYDRODYNAMICS-IMPLEMENTATION AND VERIFICATION  

SciTech Connect

We describe the Center for Radiative Shock Hydrodynamics (CRASH) code, a block-adaptive-mesh code for multi-material radiation hydrodynamics. The implementation solves the radiation diffusion model with a gray or multi-group method and uses a flux-limited diffusion approximation to recover the free-streaming limit. Electrons and ions are allowed to have different temperatures and we include flux-limited electron heat conduction. The radiation hydrodynamic equations are solved in the Eulerian frame by means of a conservative finite-volume discretization in either one-, two-, or three-dimensional slab geometry or in two-dimensional cylindrical symmetry. An operator-split method is used to solve these equations in three substeps: (1) an explicit step of a shock-capturing hydrodynamic solver; (2) a linear advection of the radiation in frequency-logarithm space; and (3) an implicit solution of the stiff radiation diffusion, heat conduction, and energy exchange. We present a suite of verification test problems to demonstrate the accuracy and performance of the algorithms. The applications are for astrophysics and laboratory astrophysics. The CRASH code is an extension of the Block-Adaptive Tree Solarwind Roe Upwind Scheme (BATS-R-US) code with a new radiation transfer and heat conduction library and equation-of-state and multi-group opacity solvers. Both CRASH and BATS-R-US are part of the publicly available Space Weather Modeling Framework.

Van der Holst, B.; Toth, G.; Sokolov, I. V.; Myra, E. S.; Fryxell, B.; Drake, R. P. [Department of Atmospheric, Oceanic and Space Sciences, University of Michigan, Ann Arbor, MI 48109 (United States); Powell, K. G. [Department of Aerospace Engineering, University of Michigan, Ann Arbor, MI 48109 (United States); Holloway, J. P. [Nuclear Engineering and Radiological Sciences, University of Michigan, Ann Arbor, MI 48109 (United States); Stout, Q. [Computer Science and Engineering, University of Michigan, Ann Arbor, MI 48109 (United States); Adams, M. L.; Morel, J. E. [Department of Nuclear Engineering, Texas A and M University, College Station, TX 77843 (United States); Karni, S. [Department of Mathematics, University of Michigan, Ann Arbor, MI 48109 (United States)

2011-06-01T23:59:59.000Z

32

ENZO+MORAY: radiation hydrodynamics adaptive mesh refinement simulations with adaptive ray tracing  

Science Journals Connector (OSTI)

......structure, which are related to energy, flux and radiation pressure...closure relation (Gonzalez, Audit Huynh 2007; Aubert Teyssier...specific intensity in units of energy per time t per solid angle per...Photon time-step E ph Photon energy E i Ionization energy of the......

John H. Wise; Tom Abel

2011-07-11T23:59:59.000Z

33

E-Print Network 3.0 - adaptive survival responses Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

Computer Technologies and Information Sciences 8 Bystander effect and adaptive response in C3H 10TK cells S. A. MITCHELL, S. A. MARINO, D. J. BRENNER and E. J. HALL Summary:...

34

Solution of the equation of radiative transfer using a NewtonKrylov approach and adaptive mesh refinement  

E-Print Network (OSTI)

Solution of the equation of radiative transfer using a Newton­Krylov approach and adaptive mesh Available online 25 November 2011 Keywords: Radiation transport Discrete ordinates method Finite ordinates method (DOM) and finite-volume method (FVM) are used exten- sively to solve the radiative transfer

Groth, Clinton P. T.

35

Surface effects on the radiation response of nanoporous Au foams  

SciTech Connect

We report on an experimental and simulation campaign aimed at exploring the radiation response of nanoporous Au (np-Au) foams. We find different defect accumulation behavior by varying radiation dose-rate in ion-irradiated np-Au foams. Stacking fault tetrahedra are formed when np-Au foams are irradiated at high dose-rate, but they do not seem to be formed in np-Au at low dose-rate irradiation. A model is proposed to explain the dose-rate dependent defect accumulation based on these results.

Fu, E. G.; Caro, M.; Wang, Y. Q.; Baldwin, K.; Caro, A. [Materials Science in Radiation and Dynamics Extremes, Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States); Zepeda-Ruiz, L. A. [Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, Livermore, California 94551 (United States); Bringa, E. [CONICET and Instituto de Ciencias Basicas, Universidad Nacional de Cuyo, Mendoza 5500 (Argentina); Nastasi, M. [Nebraska Center for Energy Sciences Research, University of Nebraska-Lincoln, Lincoln, Nebraska 68508 (United States)

2012-11-05T23:59:59.000Z

36

Molecular mechanisms of radiation carcinogenesis and the linear, non-threshold dose response model of radiation risk estimation  

Science Journals Connector (OSTI)

Recent research in molecular radiation carcinogenesis is reviewed with the specific aim of exploring the implications this research may have on the dose response relationship of radiation-induced cancer at low...

K. R. Trott; M. Rosemann

2000-06-01T23:59:59.000Z

37

Hybrid Characteristics: 3D radiative transfer for parallel adaptive mesh refinement hydrodynamics  

E-Print Network (OSTI)

We have developed a three-dimensional radiative transfer method designed specifically for use with parallel adaptive mesh refinement hydrodynamics codes. This new algorithm, which we call hybrid characteristics, introduces a novel form of ray tracing that can neither be classified as long, nor as short characteristics, but which applies the underlying principles, i.e. efficient execution through interpolation and parallelizability, of both. Primary applications of the hybrid characteristics method are radiation hydrodynamics problems that take into account the effects of photoionization and heating due to point sources of radiation. The method is implemented in the hydrodynamics package FLASH. The ionization, heating, and cooling processes are modelled using the DORIC ionization package. Upon comparison with the long characteristics method, we find that our method calculates the column density with a similarly high accuracy and produces sharp and well defined shadows. We show the quality of the new algorithm in an application to the photoevaporation of multiple over-dense clumps. We present several test problems demonstrating the feasibility of our method for performing high resolution three-dimensional radiation hydrodynamics calculations that span a large range of scales. Initial performance tests show that the ray tracing part of our method takes less time to execute than other parts of the calculation (e.g. hydrodynamics and adaptive mesh refinement), and that a high degree of efficiency is obtained in parallel execution. Although the hybrid characteristics method is developed for problems involving photoionization due to point sources, the algorithm can be easily adapted to the case of more general radiation fields.

Erik-Jan Rijkhorst; Tomasz Plewa; Anshu Dubey; Garrelt Mellema

2005-05-10T23:59:59.000Z

38

Between adaptation and resistance : labor responses to globalization in France  

E-Print Network (OSTI)

This dissertation aims at accounting for labor responses to globalization in France. It addresses this issue through a comparative study of two labor organizations-the French Democratic Labor Confederation (CFDT) and the ...

Ancelovici, Marcos, 1971-

2008-01-01T23:59:59.000Z

39

A 5-Year Investigation of Children's Adaptive Functioning Following Conformal Radiation Therapy for Localized Ependymoma  

SciTech Connect

Purpose: Conformal and intensity modulated radiation therapies have the potential to preserve cognitive outcomes in children with ependymoma; however, functional behavior remains uninvestigated. This longitudinal investigation prospectively examined intelligence quotient (IQ) and adaptive functioning during the first 5 years after irradiation in children diagnosed with ependymoma. Methods and Materials: The study cohort consisted of 123 children with intracranial ependymoma. Mean age at irradiation was 4.60 years (95% confidence interval [CI], 3.85-5.35). Serial neurocognitive evaluations, including an age-appropriate IQ measure and the Vineland Adaptive Behavior Scales (VABS), were completed before irradiation, 6 months after treatment, and annually for 5 years. A total of 579 neurocognitive evaluations were included in these analyses. Results: Baseline IQ and VABS were below normative means (P<.05), although within the average range. Linear mixed models revealed stable IQ and VABS across the follow-up period, except for the VABS Communication Index, which declined significantly (P=.015). Annual change in IQ (-.04 points) did not correlate with annual change in VABS (-.90 to +.44 points). Clinical factors associated with poorer baseline performance (P<.05) included preirradiation chemotherapy, cerebrospinal fluid shunt placement, number and extent of surgical resections, and younger age at treatment. No clinical factors significantly affected the rate of change in scores. Conclusions: Conformal and intensity modulated radiation therapies provided relative sparing of functional outcomes including IQ and adaptive behaviors, even in very young children. Communication skills remained vulnerable and should be the target of preventive and rehabilitative interventions.

Netson, Kelli L.; Conklin, Heather M. [Department of Psychology, St. Jude Children's Research Hospital, Memphis, Tennessee (United States)] [Department of Psychology, St. Jude Children's Research Hospital, Memphis, Tennessee (United States); Wu Shengjie; Xiong Xiaoping [Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee (United States)] [Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee (United States); Merchant, Thomas E., E-mail: thomas.merchant@stjude.org [Division of Radiation Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee (United States)

2012-09-01T23:59:59.000Z

40

Developing Quality Assurance Processes for Image-Guided Adaptive Radiation Therapy  

SciTech Connect

Quality assurance has long been implemented in radiation treatment as systematic actions necessary to provide adequate confidence that the radiation oncology service will satisfy the given requirements for quality care. The existing reports from the American Association of Physicists in Medicine Task Groups 40 and 53 have provided highly detailed QA guidelines for conventional radiotherapy and treatment planning. However, advanced treatment processes recently developed with emerging high technology have introduced new QA requirements that have not been addressed previously in the conventional QA program. Therefore, it is necessary to expand the existing QA guidelines to also include new considerations. Image-guided adaptive radiation therapy (IGART) is a closed-loop treatment process that is designed to include the individual treatment information, such as patient-specific anatomic variation and delivered dose assessed during the therapy course in treatment evaluation and planning optimization. Clinical implementation of IGART requires high levels of automation in image acquisition, registration, segmentation, treatment dose construction, and adaptive planning optimization, which brings new challenges to the conventional QA program. In this article, clinical QA procedures for IGART are outlined. The discussion focuses on the dynamic or four-dimensional aspects of the IGART process, avoiding overlap with conventional QA guidelines.

Yan Di [Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, MI (United States)], E-mail: dyan@beaumont.edu

2008-05-01T23:59:59.000Z

Note: This page contains sample records for the topic "radiation adaptive responses" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


41

Microsoft PowerPoint - Powerpoint_Adaptive.ppt [Compatibility Mode]  

NLE Websites -- All DOE Office Websites (Extended Search)

Response Response to Low Dose Radiation Adaptive Response Adaptive Response When large radiation When large radiation exposure is preceded by a ll " i kl " d h small "tickle" dose, the effect of the large dose is effect of the large dose is sometimes diminished The first time you go to the beach in the summer you don't usually spend 8 hours in summer, you don t usually spend 8 hours in the sun. You begin by being out an hour or d dd ddi i l i h i ki two and add additional time as their skin adapts to the sunny condition and develops protective mechanisms.... Adaptive Response Adaptive Response In some cases, cells also show an "adaptive response" to radiation, although researchers p , g are still trying to understand how the protective mechanisms work. Small doses p

42

Augmentation of Radiation Response by Motesanib, a Multikinase Inhibitor that Targets Vascular Endothelial Growth Factor Receptors  

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...measured by Image J software. Statistical significance...administration of the final radiation dose, three mice per...response by combining radiation and the vascular-damaging...Phase II study of safety and efficacy of motesanib...Data Augmentation of radiation response by motesanib...

Tim J. Kruser; Deric L. Wheeler; Eric A. Armstrong; Mari Iida; Kevin R. Kozak; Albert J. van der Kogel; Johan Bussink; Angela Coxon; Anthony Polverino; and Paul M. Harari

2010-07-15T23:59:59.000Z

43

Adaptive microbial population shifts in response to a continuous ethanol blend release increases biodegradation potential  

E-Print Network (OSTI)

Adaptive microbial population shifts in response to a continuous ethanol blend release increases 2013 Accepted 28 March 2013 Keywords: Pyrosequencing Ethanol Microbial diversity Temperature a b s t r a pilot- scale continuous release (10 months) of a 10% v:v ethanol solution mixed with benzene and toluene

Alvarez, Pedro J.

44

Ionizing Radiation Activates the Nrf2 Antioxidant Response  

Science Journals Connector (OSTI)

...Scientific). Results Ionizing radiation does not activate ARE-reporter...determine if exposure to varying doses of ionizing radiation would activate the Nrf2-ARE pathway. The radiation dose range was extended below that used...

J. Tyson McDonald; Kwanghee Kim; Andrew J. Norris; Erina Vlashi; Tiffany M. Phillips; Chann Lagadec; Lorenza Della Donna; Josephine Ratikan; Heather Szelag; Lynn Hlatky; and William H. McBride

2010-11-01T23:59:59.000Z

45

Bystander effect and adaptive response in C3H 10TK cells S. A. MITCHELL, S. A. MARINO, D. J. BRENNER and E. J. HALL  

E-Print Network (OSTI)

the bystander effect, adaptive response, genomic instabil- ity and low-dose hyper-radiosensitivity. These pheno

46

Management Perspective: Structure of Radiation Emergency Response in Japan  

Science Journals Connector (OSTI)

Due to previous local and international radiation incidents, emergency planning and preparedness measures have evolved in Japan. This chapter looks at the history of radiation emergency medicine in Japan and the ...

Takako Tominaga M.D.; Ph.D.; Misao Hachiya Ph.D.

2014-01-01T23:59:59.000Z

47

Use of the Tetrazolium Assay in Measuring the Response of Human Tumor Cells to Ionizing Radiation  

Science Journals Connector (OSTI)

...irradiation dose rate was...demonstrated a range of absorbance...RESPONSE TO IONIZING RADIATION with 1 mg...with graded doses of irradiation...each with a range of seeded...MGHU1 0 5 10 DOSE (Gy) RT112...RESPONSE TO IONIZING RADIATION 150000 FF...

Patricia Price and Trevor J. McMillan

1990-03-01T23:59:59.000Z

48

Cell cycle responses to low-dose ionizing radiation.  

Science Journals Connector (OSTI)

...47, 2006] 5178 Low-dose hyper-radiosensitivity...radiosensitivity of cells to doses of ionizing radiation less than 0.5 Gy...connection between low-dose HRS survival, Ataxia...the low dose radiation range (0-1 Gy). MR4 cells...

Sarah A. Krueger; George D. Wilson; Michael C. Joiner; and Brian Marples

2006-04-15T23:59:59.000Z

49

CpG Oligodeoxynucleotide Enhances Tumor Response to Radiation  

Science Journals Connector (OSTI)

...Massachusetts CpG oligodeoxynucleotides (ODNs) are synthetic DNA sequences containing unmethylated cytosine-guanine...radiation. | CpG oligodeoxynucleotides (ODNs) are synthetic DNA sequences containing unmethylated cytosine-guanine...

Luka Milas; Kathryn A. Mason; Hisanori Ariga; Nancy Hunter; Robert Neal; David Valdecanas; Arthur M. Krieg; John K. Whisnant

2004-08-01T23:59:59.000Z

50

Mechanisms Underlying Cellular Responses to Low Doses/Low LET Ionizing Radiation in Primary Haemopoietic Cells.  

NLE Websites -- All DOE Office Websites (Extended Search)

Mechanisms Underlying Cellular Responses to Low Doses/Low LET Ionizing Radiation Mechanisms Underlying Cellular Responses to Low Doses/Low LET Ionizing Radiation in Primary Haemopoietic Cells. Munira Kadhim 1 , Stefania Militi 1 , Debbie Bowler 1 , Denise Macdonald 1 and Kevin Prise 2 1 Radiation and Genome Stability Unit, MRC, Harwell, Didcot, Oxon, OX11 0RD, UK 2 Gray Cancer Institute ,PO Box 100, Mount Vernon Hospital, Northwood, HA6 2JR, UK Because the human population is genetically heterogeneous, it is important to understand the role that heterogeneity may play in radiation response. Exposure to ionizing radiation can lead to a suite of changes, including increased mutation rate, delayed reproductive cell death, and delayed chromosomal aberrations, all of which are manifestations of the complex genomic instability (GI) phenotype. Following exposure to either high LET

51

On the Tropospheric Response to Anomalous Stratospheric Wave Drag and Radiative Heating  

E-Print Network (OSTI)

On the Tropospheric Response to Anomalous Stratospheric Wave Drag and Radiative Heating DAVID W. J of anomalous diabatic heating in the polar stratosphere as stratospheric temperatures relax to climatology

52

The effects of emitter-tied field plates on lateral PNP ionizing radiation response  

SciTech Connect

Radiation response comparisons of lateral PNP bipolar technologies reveal that device hardening may be achieved by extending the emitter contact over the active base. The emitter-tied field plate suppresses recombination of carriers with interface traps.

Barnaby, H.J.; Schrimpf, R.D.; Cirba, C.R. [Vanderbilt Univ., Nashville, TN (United States); Pease, R.L. [RLP Research, Inc., Albuquerque, NM (United States); Fleetwood, D.M. [Sandia National Labs., Albuquerque, NM (United States); Kosier, S.L. [VTC Inc., Bloomington, MN (United States)

1998-03-01T23:59:59.000Z

53

Chronic Low Dose Radiation Effects on Radiation Sensitivity  

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Chronic Low Dose Radiation Effects on Radiation Sensitivity Chronic Low Dose Radiation Effects on Radiation Sensitivity and Chromosome Instability Induction in TK6 Cells Schwartz J.L. 1 , Jordan R. 1 , Slovic J. 1 , Moruzzi A. 1 , Kimmel R. 2 , and Liber, H.L. 3 1 University of Washington, Seattle, WA; 2 Fred Hutchinson Cancer Research Center, Seattle, WA; 3 Colorado State University, Fort Collins, Colorado There are a number of cell responses that can be detected after low dose radiation exposures including the adaptive response, low dose hypersensitivity, and induced genomic instability. The relationship between these different phenomena is unknown. In this study, we measured adaptive responses, low dose hypersensitivity, and induced genomic instability in a human B-lymphoblastoid cell model, TK6, where we could genetically modify radiation responses by either over-expression of BCL-2 or deletion of TP53. TK6

54

RADIATION CARCINOGENESIS IN MAN: INFLUENCE OF DOSE-RESPONSE MODELS AND RISK PROJECTION MODELS IN THE ESTIMATION OF RISK COEFFICIENTS FOLLOWING EXPOSURE TO LOW-LEVEL RADIATION  

E-Print Network (OSTI)

RADIATION CARCINOGENESIS IN MAN: INFLUENCE OF DOSE-RESPONSE MODELS AND RISK PROJECTION MODELS IN THE ESTIMATIONRADIATION CARCINOGENESIS IN HAN: INFLUENCE OF DOSE-RESPONSE MODELS AND RISK PROJECTION MODELS IN THE ESTIMATION

Fabrikant, J.I.

2010-01-01T23:59:59.000Z

55

Adaptive Liver Stereotactic Body Radiation Therapy: Automated Daily Plan Reoptimization Prevents Dose Delivery Degradation Caused by Anatomy Deformations  

SciTech Connect

Purpose: To investigate how dose distributions for liver stereotactic body radiation therapy (SBRT) can be improved by using automated, daily plan reoptimization to account for anatomy deformations, compared with setup corrections only. Methods and Materials: For 12 tumors, 3 strategies for dose delivery were simulated. In the first strategy, computed tomography scans made before each treatment fraction were used only for patient repositioning before dose delivery for correction of detected tumor setup errors. In adaptive second and third strategies, in addition to the isocenter shift, intensity modulated radiation therapy beam profiles were reoptimized or both intensity profiles and beam orientations were reoptimized, respectively. All optimizations were performed with a recently published algorithm for automated, multicriteria optimization of both beam profiles and beam angles. Results: In 6 of 12 cases, violations of organs at risk (ie, heart, stomach, kidney) constraints of 1 to 6 Gy in single fractions occurred in cases of tumor repositioning only. By using the adaptive strategies, these could be avoided (<1 Gy). For 1 case, this needed adaptation by slightly underdosing the planning target volume. For 2 cases with restricted tumor dose in the planning phase to avoid organ-at-risk constraint violations, fraction doses could be increased by 1 and 2 Gy because of more favorable anatomy. Daily reoptimization of both beam profiles and beam angles (third strategy) performed slightly better than reoptimization of profiles only, but the latter required only a few minutes of computation time, whereas full reoptimization took several hours. Conclusions: This simulation study demonstrated that replanning based on daily acquired computed tomography scans can improve liver stereotactic body radiation therapy dose delivery.

Leinders, Suzanne M. [Erasmus Medical Center-Daniel den Hoed Cancer Center, Rotterdam (Netherlands); Delft University of Technology, Delft (Netherlands); Breedveld, Sebastiaan; Mndez Romero, Alejandra [Erasmus Medical Center-Daniel den Hoed Cancer Center, Rotterdam (Netherlands); Schaart, Dennis [Delft University of Technology, Delft (Netherlands); Seppenwoolde, Yvette, E-mail: y.seppenwoolde@erasmusmc.nl [Erasmus Medical Center-Daniel den Hoed Cancer Center, Rotterdam (Netherlands); Heijmen, Ben J.M. [Erasmus Medical Center-Daniel den Hoed Cancer Center, Rotterdam (Netherlands)

2013-12-01T23:59:59.000Z

56

Low Dose Radiation Research Program: Low Dose Response of Respiratory Cells  

NLE Websites -- All DOE Office Websites (Extended Search)

Response of Respiratory Cells in Intact Tissues and Reconstituted Response of Respiratory Cells in Intact Tissues and Reconstituted Tissue John Ford Department of Nuclear Engineering Texas A & M University Why this Project? Using the well-established rat trachea model to test the hypothesis that normal respiratory epithelial cells transmit signals to neighboring cells in response to very low dose radiation exposure. Project Goals By comparing the responses shown by cells in these normal rodent respiratory tissues to those seen for human respiratory epithelial cells in reconstituted tissue constructs, it will be possible to better understand the responds in human respiratory cells in vivo. These studies will characterize responses after exposure to a variety of radiation types and dose distributions. Experimental Approach

57

Response of a SiC Photodiode to Extreme Ultraviolet through Visible Radiation  

SciTech Connect

The responsivity of a type 6H-SiC photodiode in the 1.5-400 nm wavelength range was measured using synchrotron radiation. The responsivity was 0.20 A/W at 270 nm and was less than 0.10 A/W in the extreme ultraviolet (EUV) region. The responsivity was calculated using a proven optical model that accounted for the reflection and absorption of the incident radiation and the variation of the charge collection efficiency (CCE) with depth into the device. The CCE was determined from the responsivity measured in the 200-400 nm wavelength range. By use of this CCE and the effective pair creation energy (7.2 eV) determined from x-ray absorption measurements, the EUV responsivity was accurately modeled with no free parameters. The measured visible-light sensitivity, although low compared with that of a silicon photodiode, was surprisingly high for this wide bandgap semiconductor.

Seely,J.; Kjornrattanawanich, B.; Holland, G.; Korde, R.

2005-01-01T23:59:59.000Z

58

Characterization of AL2O3:C thermoluminescent dosimeter response to beta radiation  

E-Print Network (OSTI)

of MASTER OF SCIENCE December 1992 Major Subject: Health Physics CHARACTERIZATION OF A1203. C THERMOLUMINES CENT DOSIMETER RESPONSE TO BETA RADIATION A Thesis by CHAD KELVIN BROWN Approved as to the style and content by: Wesley E. Bolch Chair... Radiation. (December 1992) Chad Kelvin Brown, B. S. , Georgia Institute of Technology Chair of Advisory Committee: Dr. Wesley E. Bolch Much effort has been spent searching for thermoluminescent (TL) dosimetry systems which can more accurately measure...

Brown, Chad Kelvin

2012-06-07T23:59:59.000Z

59

Response of intracerebral human glioblastoma xenografts to multifraction radiation exposures  

SciTech Connect

Purpose: We investigated the effects of fractionated radiation treatments on the life spans of athymic rats bearing intracerebral brain tumors. Methods and Materials: U-251 MG or U-87 MG human glioblastoma cells were implanted into the brains of athymic rats, and the resulting tumors were irradiated once daily with various doses of ionizing radiation for 5 consecutive days or for 10 days with a 2-day break after Day 5. Results: Five daily doses of 1 and 1.5 Gy, and 10 doses of 0.75 and 1 Gy, cured some U-251 MG tumors. However, five daily doses of 0.5 Gy increased the survival time of animals bearing U-251 MG tumors 5 days without curing any animals of their tumors. Ten doses of 0.3 Gy given over 2 weeks extended the lifespan of the host animals 9 days without curing any animals. For U-87 MG tumors, 5 daily doses of 3 Gy produced an increased lifespan of 8 days without curing any animals, and 10 doses of 1 Gy prolonged lifespan 5.5 days without curing any animals. The differences in extension of life span between the 5- and 10-fraction protocols were minor for either tumor type. Conclusion: The finding that the U-251 MG tumors are more sensitive than U-87 MG tumors, despite the fact that U-251 MG tumors contain many more hypoxic cells than U-87 MG tumors, suggests the intrinsic cellular radiosensitivities of these cell lines are more important than hypoxia in determining their in vivo radiosensitivities.

Ozawa, Tomoko [Brain Tumor Research Center, Department of Neurological Surgery, University of California San Francisco, San Francisco, CA (United States); Faddegon, Bruce A. [Department of Radiation Oncology, University of California San Francisco, San Francisco, CA (United States); Hu, Lily J. [Brain Tumor Research Center, Department of Neurological Surgery, University of California San Francisco, San Francisco, CA (United States); Bollen, Andrew W. [Department of Pathology, University of California San Francisco, San Francisco, CA (United States); Lamborn, Kathleen R. [Brain Tumor Research Center, Department of Neurological Surgery, University of California San Francisco, San Francisco, CA (United States); Deen, Dennis F. [Brain Tumor Research Center, Department of Neurological Surgery, University of California San Francisco, San Francisco, CA (United States) and Department of Radiation Oncology, University of California San Francisco, San Francisco, CA (United States)]. E-mail: ddeen@itsa.ucsf.edu

2006-09-01T23:59:59.000Z

60

E-Print Network 3.0 - adaptive radiation therapy Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

1. What is radiation ... Source: Hamza-Lup, Felix G. - School of Computing, Armstrong Atlantic State University Collection: Computer Technologies and Information Sciences...

Note: This page contains sample records for the topic "radiation adaptive responses" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


61

Galectin-1 Mediates Radiation-Related Lymphopenia and Attenuates NSCLC Radiation Response  

Science Journals Connector (OSTI)

...lung cancer (NSCLC)] and head and neck cancer patients. Results...different sites, including brain, thorax, abdomen, and pelvis...with radiation in patients with head and neck cancer (HNC). These...newly diagnosed squamous cell head and neck cancer.Head Neck...

Peiwen Kuo; Scott V. Bratman; David B. Shultz; Rie von Eyben; Cato Chan; Ziwei Wang; Carmen Say; Aparna Gupta; Bill W. Loo, Jr; Amato J. Giaccia; Albert C. Koong; Maximilian Diehn; Quynh-Thu Le

2014-11-01T23:59:59.000Z

62

Mechanisms underlying cellular responses of cells from haemopoeitic tissue to low dose-low LET radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

underlying cellular responses of cells from haemopoeitic underlying cellular responses of cells from haemopoeitic tissue to low dose-low LET radiation Munira Kadhim 1 , Sarah Irons 1 , Deborah Bowler 1 , Virginia Serra 1 , Stefania Militi 2 , Kim Chapman 1 1 Genomic Instability Research Group, School of Life Sciences, Oxford Brookes University, Gipsy Lane, Headington, Oxford, Oxfordshire, OX3 0BP, UK 2 Mammalian Genetics Unit, Medical Research Council Harwell, Harwell Science and Innovation Campus, Oxfordshire, OX11 0RD, UK Radiation-induced responses at the cellular and whole body levels are influenced by genetic predisposition, with implications for environmental and potentially, diagnostic exposures. Currently, the extent to which genetic background play a role in the mechanisms and signalling pathways involved in radiation-induced

63

An integrated genetics approach to systemic low-dose radiation responses  

NLE Websites -- All DOE Office Websites (Extended Search)

integrated genetics approach to systemic low-dose radiation responses integrated genetics approach to systemic low-dose radiation responses G. Huang 1 , Y. Huang 1 , D.H. Nguyen 1 , K. Bjornstad 1 , C. Rosen 1 , P. Chang 2 , R. DelRosario 3 , Do Yup Lee 1 , B. Bowen 1 , W. Reindl 1 , J. Mott 1 , A. Balmain 3 , M.H. Barcellos-Hoff 4 , Joe W Gray 1,5 , Mina Bissell 1 , Gary Karpen 1 , T. Northen 1 , E. A. Blakely 1 , J. H. Mao 1 1 Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 2 SRI International, Menlo Park, CA

64

Cellular response to low dose radiation: Role of phosphatidylinositol-3 kinase like kinases  

SciTech Connect

It is increasingly realized that human exposure either to an acute low dose or multiple chronic low doses of low LET radiation has the potential to cause different types of cancer. Therefore, the central theme of research for DOE and NASA is focused on understanding the molecular mechanisms and pathways responsible for the cellular response to low dose radiation which would not only improve the accuracy of estimating health risks but also help in the development of predictive assays for low dose radiation risks associated with tissue degeneration and cancer. The working hypothesis for this proposal is that the cellular mechanisms in terms of DNA damage signaling, repair and cell cycle checkpoint regulation are different for low and high doses of low LET radiation and that the mode of action of phosphatidylinositol-3 kinase like kinases (PIKK: ATM, ATR and DNA-PK) determines the dose dependent cellular responses. The hypothesis will be tested at two levels: (I) Evaluation of the role of ATM, ATR and DNA-PK in cellular response to low and high doses of low LET radiation in simple in vitro human cell systems and (II) Determination of radiation responses in complex cell microenvironments such as human EpiDerm tissue constructs. Cellular responses to low and high doses of low LET radiation will be assessed from the view points of DNA damage signaling, DNA double strand break repair and cell cycle checkpoint regulation by analyzing the activities (i.e. post-translational modifications and kinetics of protein-protein interactions) of the key target proteins for PI-3 kinase like kinases both at the intra-cellular and molecular levels. The proteins chosen for this proposal are placed under three categories: (I) sensors/initiators include ATM ser1981, ATR, 53BP1, gamma-H2AX, MDC1, MRE11, Rad50 and Nbs1; (II) signal transducers include Chk1, Chk2, FANCD2 and SMC1; and (III) effectors include p53, CDC25A and CDC25C. The primary goal of this proposal is to elucidate the differences in cellular defense mechanisms between low and high doses of low LET radiation and to define the radiation doses where the cellular DNA damage signaling and repair mechanisms tend to shift. This information is critically important to address and advance some of the low dose research program objectives of DOE. The results of this proposed study will lead to a better understanding of the mechanisms for the cellular responses to low and high doses of low LET radiation. Further, systematic analysis of the role of PIKK signaling pathways as a function of radiation dose in tissue microenvironment will provide useful mechanistic information for improving the accuracy of radiation risk assessment for low doses. Knowledge of radiation responses in tissue microenvironment is important for the accurate prediction of ionizing radiation risks associated with cancer and tissue degeneration in humans.

Balajee, A.S.; Meador, J.A.; Su, Y.

2011-03-24T23:59:59.000Z

65

Low Dose Radiation Induced DNA Damage Signaling and Repair Responses in  

NLE Websites -- All DOE Office Websites (Extended Search)

Induced DNA Damage Signaling and Repair Responses in Induced DNA Damage Signaling and Repair Responses in Human 3-Dimensional Skin Model System Yanrong Su, Jarah Meador and Adayabalam S. Balajee Center for Radiological Research, College of Physicians and Surgeons, Columbia University, 630 West, 168th Street, New York, NY 10032. Exposure to ionizing radiation (IR) inflicts a wide variety of lesions in the genomic DNA. Among them, DNA double strand break (DSB) is considered to be the critical lesion for most of the deleterious radiation effects including carcinogenesis. Much of our knowledge on induction and repair kinetics of DSB has come from studies in two dimensional cell culture systems. However, the damage signaling and repair responses to DSB in tissue microenvironment are largely unknown. Knowledge of tissue responses to

66

Mechanisms underlying cellular responses of cells from haemopoietic tissue to low dose/low LET radiation  

SciTech Connect

To accurately define the risks associated with human exposure to relevant environmental doses of low LET ionizing radiation, it is necessary to completely understand the biological effects at very low doses (i.e., less than 0.1 Gy), including the lowest possible dose, that of a single electron track traversal. At such low doses, a range of studies have shown responses in biological systems which are not related to the direct interaction of radiation tracks with DNA. The role of these non-targeted responses in critical tissues is poorly understood and little is known regarding the underlying mechanisms. Although critical for dosimetry and risk assessment, the role of individual genetic susceptibility in radiation risk is not satisfactorily defined at present. The aim of the proposed grant is to critically evaluate radiation-induced genomic instability and bystander responses in key stem cell populations from haemopoietic tissue. Using stem cells from two mouse strains (CBA/H and C57BL/6J) known to differ in their susceptibility to radiation effects, we plan to carefully dissect the role of genetic predisposition on two non-targeted radiation responses in these models; the bystander effect and genomic instability, which we believe are closely related. We will specifically focus on the effects of low doses of low LET radiation, down to doses approaching a single electron traversal. Using conventional X-ray and ?-ray sources, novel dish separation and targeted irradiation approaches, we will be able to assess the role of genetic variation under various bystander conditions at doses down to a few electron tracks. Irradiations will be carried out using facilities in routine operation for bystander targeted studies. Mechanistic studies of instability and the bystander response in different cell lineages will focus initially on the role of cytokines which have been shown to be involved in bystander signaling and the initiation of instability. These studies also aim to uncover protein mediators of the bystander responses using advanced proteomic screening of factors released from irradiated, bystander and unstable cells. Integral to these studies will be an assessment of the role of genetic susceptibility in these responses, using CBA/H and C57BL/6J mice. The relevance of in vivo interactions between stem cells and the stem cell niche will be explored in the future by re-implantation techniques of previously irradiated cells. The above studies will provide fundamental mechanistic information relating genetic predisposition to important low dose phenomena, and will aid in the development of Department of Energy policy, as well as radiation risk policy for the public and the workplace. We believe the proposed studies accurately reflect the goals of the DOE low dose program.

Munira A Kadhim

2010-03-05T23:59:59.000Z

67

Annexin A2 Regulates A Low Dose-Specific Stress Response To Radiation.  

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Annexin A2 Regulates A Low Dose-Specific Stress Response To Radiation. Thomas J. Annexin A2 Regulates A Low Dose-Specific Stress Response To Radiation. Thomas J. Weber (PI), Greg J. Newton, Ryan D. Quesenberry, Janani I. Shutthanandan, Nikki Bollinger, Heather E. Engelmann and Lee K. Opresko. Cell Biology and Biochemistry Group, Pacific Northwest National Laboratory, Richland, WA 99354. Previous studies have demonstrated that JB6 cells release cell transforming paracrine factors following exposure to a low dose of radiation (10 cGy). Investigation of secreted proteins by SDS-Page and silver stain led to the identification of a 36 kDa band whose levels were increased in medium from irradiated cells, relative to sham controls. The 36 kDa band was identified as annexin A2 by mass spectrometry. Western blot analysis confirmed a dose-dependent increase in annexin A2 levels associated with medium from

68

Proteomic and Biochemical Studies of Human Mesenchymal Stem Cells in Response to Low Dose Ionizing Radiation  

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Proteomic and Biochemical Studies of Human Mesenchymal Stem Cells Proteomic and Biochemical Studies of Human Mesenchymal Stem Cells in Response to Low Dose Ionizing Radiation Deok-Jin Jang 1 , Mingquan Guo 1 , Julia S.F.Chu 2 , Kyle T. Kurpinski 2 , Bjorn Rydberg 1 , Song Li 2 , and Daojing Wang 1 1. Life Sciences Division, Lawrence Berkeley National Lab, Berkeley, CA 94720 2. Department of Bioengineering, University of California, Berkeley, CA 94720 We will present data obtained during the first year of our DOE/NASA Low Dose Radiation Research program. We utilized a comprehensive approach including transcriptomics, proteomics, phosphoproteomics, and biochemistry to characterize human mesenchymal stem cells (MSCs) in response to low dose ionizing radiation. We first determined the cell survival, proliferation, and osteogenic differentiation of

69

Low Dose Radiation Research Program: Mechanisms of Tissue Response to Low  

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Tissue Response to Low Dose Radiation Tissue Response to Low Dose Radiation Mary Helen Barcellos-Hoff Lawrence Berkeley National Laboratory Why This Project? In the past, the effects of ionizing radiation on humans has been attributed in great part to its ability to damage DNA, which transmits information from cell to cell, and generation to generation. Damaged DNA can lead to cell death or perpetuate the damage to daughter cells and to future generations. In addition to the information contained with the genome (i.e., DNA sequence), information directing cell behavior and tissue function is also stored outside the DNA. The success in cloning sheep from the DNA contained in the nucleus of an adult cell shows how important signals from the outside are in defining how the genome is expressed. This

70

Low Dose Radiation Research Program: Low Dose Response of Respiratory Cells  

NLE Websites -- All DOE Office Websites (Extended Search)

Low Dose Radiation Research Program: Low Dose Response of Respiratory Low Dose Radiation Research Program: Low Dose Response of Respiratory Cells in Intact Tissues and Reconstituted Tissue Constructs Authors: John Ford, Amy Maslowski, Alex Redd and Les Braby Institutions: Texas A&M University, College Station, TX We are developing a model of respiratory tissue using a perfusion culture system. We are using this system to quantify the effects of normal tissue architecture, and the interaction of epithelial cells with other cell types, on radiation-induced bystander effects. Tracheal tissue taken from young adult Fischer 344 rats is imbedded in a growth factor enriched agarose matrix. The chamber is designed to allow growth medium to periodically wash the epithelial surface of the tracheal lumen while maintaining the air-interface that is necessary for the normal

71

Technical note Energy response of the new EBT2 radiochromic film to x-ray radiation  

E-Print Network (OSTI)

.5% from 50 kVp to 10 MV. This produces a slightly smaller and thus even more energy independent film thanTechnical note Energy response of the new EBT2 radiochromic film to x-ray radiation Martin J Science, City University of Hong Kong, Kowloon Tong, Hong Kong b Illawarra Cancer Care Centre, Department

Yu, K.N.

72

A Novel Alternative Approach for Prediction of Radiation Response of Squamous Cell Carcinoma of Head and Neck  

Science Journals Connector (OSTI)

...distance available in the software STATISTICA (StatSoft...was generated by the software. Results Differential...Tumor-related Genes from Radiation-sensitive and Radiation-resistant...toxicology, and drug safety evaluation. Cancer...approach for prediction of radiation response of squamous...

Ehab Hanna; Dennis C. Shrieve; Vaneerat Ratanatharathorn; Xueqing Xia; Randy Breau; James Suen; and Shulin Li

2001-03-03T23:59:59.000Z

73

Human In vivo Dose-Response to Controlled, Low-Dose Low Linear Energy Transfer Ionizing Radiation Exposure  

Science Journals Connector (OSTI)

...effects of low-dose low-linear energy transfer ionizing radiation (LDIR) in humans...direct evidence that doses in the range of 1 to 10 cGy...the intentional radiation of healthy tissue...the response to ionizing radiation. Attempts...

Zelanna Goldberg; David M. Rocke; Chad Schwietert; Susanne R. Berglund; Alison Santana; Angela Jones; Jrg Lehmann; Robin Stern; Ruixiao Lu; and Christine Hartmann Siantar

2006-06-15T23:59:59.000Z

74

Nonlinear vs. bolometric radiation response and phonon thermal conductance in graphene-superconductor junctions  

SciTech Connect

Graphene is a promising candidate for building fast and ultra-sensitive bolometric detectors due to its weak electron-phonon coupling and low heat capacity. In order to realize a practical graphene-based bolometer, several important issues, including the nature of radiation response, coupling efficiency to the radiation and the thermal conductance need to be carefully studied. Addressing these issues, we present graphene-superconductor junctions as a viable option to achieve efficient and sensitive bolometers, with the superconductor contacts serving as hot electron barriers. For a graphene-superconductor device with highly transparent interfaces, the resistance readout in the presence of radio frequency radiation is dominated by non-linear response. On the other hand, a graphene-superconductor tunnel device shows dominantly bolometric response to radiation. For graphene devices fabricated on SiO{sub 2} substrates, we confirm recent theoretical predictions of T{sup 2} temperature dependence of phonon thermal conductance in the presence of disorder in the graphene channel at low temperatures.

Vora, Heli; Nielsen, Bent; Du, Xu [Department of Physics and Astronomy, Stony Brook University, Stony Brook, New York (United States)

2014-02-21T23:59:59.000Z

75

Modular Systems Biology applied to TGFbeta and DNA Damage Response Signaling following Low Dose Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Modular Systems Biology applied to TGFbeta and DNA Damage Response Signaling following Modular Systems Biology applied to TGFbeta and DNA Damage Response Signaling following Low Dose Radiation Francis A. Cucinotta 1 , Yongfeng Li 2 , Minli Wang 2 , Claudio Carra 2 , Janice Pluth 3 , and Peter O'Neill 4 1 NASA Johnson Space Center, Houston, TX 2 U.S.R.A. Division of Life Sciences, Houston TX 3 Lawrence Berkeley National Laboratory, Berkeley CA 4 Oxford University, Oxford UK Abstract: Modular systems biology (MSB) describes the complexity of biological systems using well defined modules that represent distinct biological response pathways or sub-systems within pathways. We review mathematical concepts from control theory that can be used to identify and construct well defined modules for describing complex biological processes. The DNA damage response and TGFbeta/Smad signaling are two important response pathways following

76

STOCHASTIC MODELS OF SPACE RADIATION DNA DAMAGE RESPONSES AND CANCER RISKS  

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STOCHASTIC MODELS OF SPACE RADIATION DNA DAMAGE STOCHASTIC MODELS OF SPACE RADIATION DNA DAMAGE RESPONSES AND CANCER RISKS Francis A. Cucinotta 1 , Janice M. Pluth 2 , Artem Ponomarev 3 , Shaowen Hu 3 , Jennifer Anderson 4 , Jane Harper 4 , and Peter O'Neill 4 1 NASA Lyndon B. Johnson Space Center, Houston TX, USA; 2 Lawrence Berkeley National Laboratory, Berkeley CA, USA; 3 U.S.R.A., Division of Life Sciences, Houston TX, USA; 4 MRC Radiation and Genome Stability Unit, Harwell, Didcot, UK Abstract: On space missions astronauts are exposed to a steady flux of galactic cosmic rays (GCR) consisting of high-energy protons and heavy ions. In the next decades long- term missions of up to 200 days to the Earth's moon and 1100 days to Mars are planed by NASA where cumulative doses will not be low (>100 mSv) albeit dose-

77

Low Dose Radiation Research Program: Low-Dose Dose-Response of  

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Low-Dose Dose-Response of Proliferating Human Cells Exposed to Low Low-Dose Dose-Response of Proliferating Human Cells Exposed to Low Dose Rate g-Radiation. Authors: Louise Enns,1 Michael Weinfeld,1 Albert Murtha,1 and Kenneth Bogen2 Institutions: 1Cross Cancer Institute and 2Lawrence Livermore National Laboratory. Clinical and environmental exposure to ionizing radiation rarely exceeds 200 cGy. To examine cell proliferation at early times (up to 5 days) post-irradiation, we are utilizing an assay in which single cells encapsulated within ~30- to 70-µm-diameter agarose gel microdrops (GMDs) are exposed and cultured for 4 days at 37°C, then analyzed by flow cytometry (FC). Clonogenic proliferation is measured as the fraction of occupied GMDs containing multicellular microcolonies after 4 days in culture. This assay was applied to human A549 lung cells exposed to gamma

78

Adaptive response by single cell radiation hits?implications for nuclear workers  

Science Journals Connector (OSTI)

......and F r, for radioprotective AR for the four AR datasets showing mean single hits. Shown also are the...With respect to radioprotection in the event of a nuclear accident exposure of nuclear workers, Shadley and Wolfe(12) show a significant......

Bobby E. Leonard

2005-12-20T23:59:59.000Z

79

Response of five tropical plant species to natural solar ultraviolet-B radiation  

SciTech Connect

The tropical latitudes currently receive high solar ultraviolet-B radiation (UV-B, 280-320 nm) even without ozone depletion. Thus, the influence of natural, present-day UV-B irradiance was examined for three native rainforest tree species and two economically important species on Barro Colorado Island, Panama (9[degrees] N). Solar UV-B radiation conditions were obtained using a UV-B excluding plastic film or a near-ambient UV-B transmitting film over potted plants in a small clearing. Significant differences were often exhibited as increased foliar UV-B absorbing compounds, increased leaf mass pre area, and reduced leaf blade length for plants receiving solar UV-B radiation. Plant height was typically reduced under solar UV-B, but some variation among species in response was seen. Biomass and photosystem II function were generally unaffected. The results provide evidence that tropical vegetation responds to the present level of Solar UV-B radiation. This suggests even a small increase in UV-B radiation with ozone depletion may have biological implications.

Searles, P.S.; Caldwell, M.M. (Utah State Univ., Logan, UT (United States)); Winter, K. (Smithsonian Tropical Research Institute, Balboa (Panama))

1994-06-01T23:59:59.000Z

80

NFkB in the Thiol-Induced Adaptive Response (A)  

NLE Websites -- All DOE Office Websites (Extended Search)

A) A) David Grdina The University of Chicago Abstract Exposure of cells to low non-lethal doses of ionizing radiation (≤ 10 cGy) or WR1065, the active free thiol form of amifostine, can induce pro-survival pathways that result in protection against the damaging effects of a 2 Gy dose of ionizing radiation. One such signaling pathway involves the activation of NFκB and the subsequent elevation of active manganese superoxide dismutase (SOD2). SOD2 is a mitochondrial matrix protein that serves as the primary mitochondrial defense against superoxide formation. Its primary function is to facilitate the dismutation of two molecules of superoxide anion (O2-) produced by normal respiratory processes or following exposure to ionizing radiation into water and hydrogen peroxide. To characterize the role of SOD2 in the radiation- and

Note: This page contains sample records for the topic "radiation adaptive responses" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


81

Non-climatic thermal adaptation: implications for species' responses to climate warming  

Science Journals Connector (OSTI)

...Grahamstown, South Africa 3 The Swire Institute of...non-climatic heat sources (solar and geothermal) seems likely...Wald 2001 The European solar radiation atlas: a valuable digital tool. Solar Energy 71, 81-83. ( doi:10...

2010-01-01T23:59:59.000Z

82

Dropouts of the outer electron radiation belt in response to solar wind stream interfaces: global positioning system observations  

Science Journals Connector (OSTI)

...radiation belt in response to solar wind stream interfaces: global...Calgary, Calgary, Alberta, Canada We present a statistical study...examined statistically for 67 solar wind stream interfaces (SIs...global positioning system|solar wind| 1. Introduction (a...

2010-01-01T23:59:59.000Z

83

Human In vivo Dose-Response to Controlled, Low-Dose Low Linear Energy Transfer Ionizing Radiation Exposure  

Science Journals Connector (OSTI)

...biotinylated nucleotide analogue/ribonucleotide mix. The biotinylated cRNA targets were then...dose-response to controlled, low-dose low linear energy transfer ionizing radiation exposure. | The effect of low doses of low-linear energy transfer (photon) ionizing radiation...

Zelanna Goldberg; David M. Rocke; Chad Schwietert; Susanne R. Berglund; Alison Santana; Angela Jones; Jrg Lehmann; Robin Stern; Ruixiao Lu; and Christine Hartmann Siantar

2006-06-15T23:59:59.000Z

84

Ethylene is not involved in adaptive responses to flooding in the Amazonian wild rice species Oryza grandiglumis  

Science Journals Connector (OSTI)

Abstract The Amazonian wild rice Oryza grandiglumis has two contrasting adaptation mechanisms to flooding submergence: a quiescence response to complete submergence at the seedling stage and an escape response based on internodal elongation to partial submergence at the mature stage. We investigated possible factors that trigger these responses. In stem segments excised from mature O. grandiglumis plants, complete submergence only slightly promoted internodal elongation with increased ethylene levels in the internodes, while partial submergence substantially promoted internodal elongation without increased ethylene levels in the internodes. Incubation of non-submerged stem segments under a continuous flow of humidified ethylene-free air promoted internodal elongation to the same extent as that observed for partially submerged segments. Applied ethylene had little effect on the internodal elongation of non-submerged segments irrespective of humidity conditions. These results indicate that the enhanced internodal elongation of submerged O. grandiglumis plants is not triggered by ethylene accumulated during submergence but by the moist surroundings provided by submergence. The growth of shoots in O. grandiglumis seedlings was not promoted by ethylene or complete submergence, as is the case in O. sativa cultivars possessing the submergence-tolerant gene SUB1A. However, because the genome of O. grandiglumis lacks the SUB1A gene, the quiescence response of O. grandiglumis seedlings to complete submergence may be regulated by a mechanism distinct from that involved in the response of submergence-tolerant O. sativa cultivars.

Takuma Okishio; Daisuke Sasayama; Tatsuya Hirano; Masahiro Akimoto; Kazuyuki Itoh; Tetsushi Azuma

2015-01-01T23:59:59.000Z

85

E-Print Network 3.0 - affect radiation response Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

12;Radiative Forcings: Shortwave Forcings... What about gases that affect the greenhouse effect? Radiative forcing for greenhouse gases: Instantly... ;Radiative Forcings In ......

86

E-Print Network 3.0 - adaptive metabolic response Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

bass (Micropterus salmoides) Summary: factor, there are a range of responses depending on test conditions and baseline metabolic rate... for greater differences in metabolic rate...

87

E-Print Network 3.0 - adaptive melanin response Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

Biology and Medicine 3 Cutaneous melanin exhibiting fluorescence emission under near-infrared light excitation Summary: of the major fluorophores responsible for...

88

The effect of different adaptation strengths on image quality and radiation dose using Siemens Care Dose 4D  

Science Journals Connector (OSTI)

......undertaking strategies for CT radiation dose optimisation...supported by the Swedish Radiation Safety Authority (SSI P 1579...4D new technique for radiation dose reduction. SOMATOM...Application Guide. Software Version syngo CT 2005A......

Marcus Sderberg; Mikael Gunnarsson

2010-01-01T23:59:59.000Z

89

EMSL Research and Capability Development Proposals Nonlinear Radiation Response and Transport Properties in Scintillating Materials  

NLE Websites -- All DOE Office Websites (Extended Search)

Figure 1. Time-of-Flight (TOF) versus light Figure 1. Time-of-Flight (TOF) versus light output (L) of CsI:Tl to He + ions. The inset is an example where L=263 is determined for particles with certainty energy (TOF=840). The energy resolution can be determined by ∆L/L = 45/263. The light-energy dependence and energy resolution can be observed as the difference in curvature and dispersive of the data. EMSL Research and Capability Development Proposals Nonlinear Radiation Response and Transport Properties in Scintillating Materials Project start date: Spring 2007 EMSL Lead Investigator: Yanwen Zhang Deposition and Microfabrication, EMSL, PNNL Co-investigators: Vaithiyalingam Shutthanandan Deposition and Microfabrication, EMSL, PNNL Scintillation response has wide applications in the field of astronomy, medical physics, high-energy

90

Validated Models for Radiation Response and Signal Generation in Scintillators: Final Report  

SciTech Connect

This Final Report presents work carried out at Pacific Northwest National Laboratory (PNNL) under the project entitled Validated Models for Radiation Response and Signal Generation in Scintillators (Project number: PL10-Scin-theor-PD2Jf) and led by Drs. Fei Gao and Sebastien N. Kerisit. This project was divided into four tasks: 1) Electronic response functions (ab initio data model) 2) Electron-hole yield, variance, and spatial distribution 3) Ab initio calculations of information carrier properties 4) Transport of electron-hole pairs and scintillation efficiency Detailed information on the results obtained in each of the four tasks is provided in this Final Report. Furthermore, published peer-reviewed articles based on the work carried under this project are included in Appendix. This work was supported by the National Nuclear Security Administration, Office of Nuclear Nonproliferation Research and Development (DNN R&D/NA-22), of the U.S. Department of Energy (DOE).

Kerisit, Sebastien N.; Gao, Fei; Xie, YuLong; Campbell, Luke W.; Van Ginhoven, Renee M.; Wang, Zhiguo; Prange, Micah P.; Wu, Dangxin

2014-12-01T23:59:59.000Z

91

Thermoluminescence response of new KClXBr1?X:EuCl3 sintered phosphors exposed to beta and gamma radiation  

Science Journals Connector (OSTI)

......the dosimetric response for samples of...4. Dosimetric response of composition...understand the radiation storage capability of each...thermoluminescence response of KClXBr1-X...calculation of activation energies and frequency factors from glow......

R. Bernal; E. Cruz-Zaragoza; C. Cruz-Vzquez; S. E. Burruel-Ibarra; M. J. Rivera-Flores; M. Barboza-Flores

2006-09-01T23:59:59.000Z

92

PARP-1, PARP-2, and the cellular response to low doses of ionizing radiation  

Science Journals Connector (OSTI)

Purpose Poly(ADP-ribose) polymerase-1 (PARP-1) is rapidly and directly activated by single-strand breaks and is required for efficient base excision repair. These properties indicate that inhibition of PARP-1 might enhance the cellular response to low doses of radiation. We tested the effect of chemical inhibition of PARP-1 on low-dose clonogenic survival in a number of cell lines and the low-dose radiation response of a PARP-1 knockout murine cell line. Methods and materials Clonogenic cell survival of V79-379A and CHO-K1 hamster fibroblasts, T98G and U373-MG human glioma cells, and 3T3 mouse embryo fibroblast PARP-1 knockout cells was measured using a precise flow cytometry-based plating assay. Chemical inhibitors of PARP enzymes were tested for their effect on clonogenic survival after a range of ionizing radiation doses. Results Chemical inhibition of PARP activity induced marked radiosensitization of V79, CHO, and exponentially growing T98G cells in the 0.050.3-Gy range. This effect was not seen in U373 cells or in confluent T98G populations. Low-dose radiosensitization was not apparent in PARP-1 knockout cells. Conclusion Low-dose radiosensitization of actively dividing tumor cells by PARP-1 inhibitors suggests that they may have a role in enhancing the efficacy of ultrafractionated or low-dose-rate radiotherapy regimens. We hypothesize that PARP-2 compensates for the absence of PARP-1 in the knockout cell line.

Anthony Chalmers; Peter Johnston; Mick Woodcock; Michael Joiner; Brian Marples

2004-01-01T23:59:59.000Z

93

The Polyamine Catabolic Enzyme SAT1 Modulates Tumorigenesis and Radiation Response in GBM  

Science Journals Connector (OSTI)

...Introduction Exposure to ionizing radiation is a well-established...moderate to high-dose radiation exposure. Examples include...atomic bomb survivors in Japan, women treated with repeated exposure to radiation from fluoroscopic chest...

Adina Brett-Morris; Bradley M. Wright; Yuji Seo; Vinay Pasupuleti; Junran Zhang; Jun Lu; Raffaella Spina; Eli E. Bar; Maneesh Gujrati; Rebecca Schur; Zheng-Rong Lu; and Scott M. Welford

2014-12-01T23:59:59.000Z

94

Quantitative High Content Imaging of Cellular Adaptive Stress Response Pathways in Toxicity for Chemical Safety Assessment  

Science Journals Connector (OSTI)

Steven Wink , Steven Hiemstra , Suzanna Huppelschoten , Erik Danen , Marije Niemeijer , Giel Hendriks , Harry Vrieling , Bram Herpers , and Bob van de Water * ... (37-39) The true power of HCS using automated imagers lies in its ability to capture when and where specific molecular signaling events are taking place, enabling characterization of cellular responses to multiple changes in the environment with high time and spatial resolution, relatively high throughput (depending on the exact setup) and on a single cell basis, enabling the detection of heterogeneity within populations. ... (141) The members of this family are highly expressed in the liver and include PXR, RXR, CAR, AHR, and HXR. ...

Steven Wink; Steven Hiemstra; Suzanna Huppelschoten; Erik Danen; Marije Niemeijer; Giel Hendriks; Harry Vrieling; Bram Herpers; Bob van de Water

2014-01-22T23:59:59.000Z

95

Prognosis of patients with advanced carcinoma of the esophagus with complete response to chemotherapy and/or radiation therapy: a questionnaire survey in Japan  

Science Journals Connector (OSTI)

Background....We estimated the survival of patients with advanced carcinoma of the esophagus in Japan who achieved complete response (CR) with chemotherapy and/or radiation therapy.

N. Aoyama; H. Koizumi; J. Minamide

2001-06-01T23:59:59.000Z

96

Low Dose Radiation Research Program: Research Institutions  

NLE Websites -- All DOE Office Websites (Extended Search)

Institutions Institutions Lovelace Respiratory Research Institute Biological Bases for Radiation Adaptive Responses in the Lung-Lovelace Respiratory Research Institute, Albuquerque, NM USA Contact: Dr. Bobby R. Scott Program Objective Our research focuses on elucidating the biological bases for radiation adaptive responses in the lung and for suppressing lung cancer, and to use the knowledge gained to produce an improved systems-biology-based, risk model for lung cancer induction by low-dose, low linear-energy-transfer (LET) radiation. Research was initiated in October 2009. This research should help foster a new era of low-dose radiation risk/benefit assessment. It will have important implications for possible use of low-dose diagnostic radiation (e.g., X-rays) in cancer therapy. It

97

Characterization of Cell Cycle Checkpoint Responses after Ionizing Radiation in Nijmegen Breakage Syndrome Cells  

Science Journals Connector (OSTI)

...events leading to G, and G2 arrests following ionizing radiation is abnormal in cells from AT patients. p53 protein up- regulation following low doses of ionizing radiation ranges from delayed and reduced to completely absent...

Vikky Yamazaki; Rolf-Dieter Wegner; and Cordula U. Kirchgessner

1998-06-01T23:59:59.000Z

98

Physiological Responses of the Hyperthermophilic Archaeon Pyrococcus abyssi to DNA Damage Caused by Ionizing Radiation  

Science Journals Connector (OSTI)

...Damage Caused by Ionizing Radiation Edmond Jolivet 1 Corresponding...Fukuoka 812-8581, Japan The mechanisms by which...temperature and/or ionizing radiation. The hyperthermophilic...Matsunaga thanks the Japan Society for the Promotion...resistant to ionizing radiation? Trends Microbiol...

Edmond Jolivet; Fujihiko Matsunaga; Yoshizumi Ishino; Patrick Forterre; Daniel Prieur; Hannu Myllykallio

2003-07-01T23:59:59.000Z

99

ATM Requirement in Gene Expression Responses to Ionizing Radiation in Human Lymphoblasts and Fibroblasts  

Science Journals Connector (OSTI)

...St. Charles, MO) software program. A two-dimensional...analysis was done using software and methods as described...ATM kinase by ionizing radiation and phosphorylation...toxicology, and drug safety evaluation. Cancer...exposure to ionizing radiation. Radiat Res 2000...

Cynthia L. Innes; Alexandra N. Heinloth; Kristina G. Flores; Stella O. Sieber; Paula B. Deming; Pierre R. Bushel; William K. Kaufmann; and Richard S. Paules

2006-03-01T23:59:59.000Z

100

Physiological Responses of the Hyperthermophilic Archaeon Pyrococcus abyssi to DNA Damage Caused by Ionizing Radiation  

Science Journals Connector (OSTI)

...before and after radiation and was in good...performed at a sublethal dose of 2,000 Gy to...our preliminary estimation reveals that 0...been observed for radiation-resistant Chroococcidiopsis...caused by ionizing radiation. | The mechanisms...furiosus, survive high doses of ionizing gamma...

Edmond Jolivet; Fujihiko Matsunaga; Yoshizumi Ishino; Patrick Forterre; Daniel Prieur; Hannu Myllykallio

2003-07-01T23:59:59.000Z

Note: This page contains sample records for the topic "radiation adaptive responses" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


101

Modeling marrow damage from response data: Morphallaxis from radiation biology to benzene toxicity  

SciTech Connect

Consensus principles from radiation biology were used to describe a generic set of nonlinear, first-order differential equations for modeling of toxicity-induced compensatory cell kinetics in terms of sublethal injury, repair, direct killing, killing of cells with unrepaired sublethal injury, and repopulation. This cellular model was linked to a probit model of hematopoietic mortality that describes death from infection and/or hemorrhage between {approximately} 5 and 30 days. Mortality data from 27 experiments with 851 doseresponse groups, in which doses were protracted by rate and/or fractionation, were used to simultaneously estimate all rate constants by maximum-likelihood methods. Data used represented 18,940 test animals distributed according to: (mice, 12,827); (rats, 2,925); (sheep, 1,676); (swine, 829); (dogs, 479); and (burros, 204). Although a long-term, repopulating hematopoietic stem cell is ancestral to all lineages needed to restore normal homeostasis, the dose-response data from the protracted irradiations indicate clearly that the particular lineage that is ``critical`` to hematopoietic recovery does not resemble stem-like cells with regard to radiosensitivity and repopulation rates. Instead, the weakest link in the chain of hematopoiesis was found to have an intrinsic radioresistance equal to or greater than stromal cells and to repopulate at the same rates. Model validation has been achieved by predicting the LD{sub 50} and/or fractional group mortality in 38 protracted-dose experiments (rats and mice) that were not used in the fitting of model coefficients.

Jones, T.D.; Morris, M.D.; Hasan, J.S.

1995-12-01T23:59:59.000Z

102

Low Dose Radiation Program: Workshop VI Abstracts  

NLE Websites -- All DOE Office Websites (Extended Search)

Workshop VI Principal Investigator and Abstracts Workshop VI Principal Investigator and Abstracts Anderson, Carl Whole Genome Analysis of Functional Protein Binding Sites and DNA Methylation: Application to p53 and Low Dose Ionizing Radiation. Averbeck, Dietrich Cellular Responses at Low Doses of Ionizing Radiation. Azzam, Edouard Adaptive Responses to Low Dose/Low Dose-Rate ?-Rays in Normal Human Fibroblasts: The Role of Oxidative Metabolism. Bailey, Susan The Role of Telomere Dysfunction in Driving Genomic Instability. Balajee, Adayabalam Low Dose Radiation Induced DNA Damage Signaling and Repair Responses in Human 3-Dimensional Skin Model System. Barcellos-Hoff, Mary Helen Imaging Bioinformatics for Mapping Multidimensional Responses. Barcellos-Hoff, Mary Helen Biological Response to Radiation Mediated through the Microenvironment and

103

Low Dose Radiation Research Program: Regulation of NF-kB and MnSOD in Low  

NLE Websites -- All DOE Office Websites (Extended Search)

NF-kB and MnSOD in Low Dose Radiation-Induced Adaptive NF-kB and MnSOD in Low Dose Radiation-Induced Adaptive Responses in Mouse and Human Skin Cells Jian Jian Li School of Health Sciences, Purdue University West Lafayette, Indiana Why this Project? To determine if low dose ionizing radiation-induced adaptive responses in skin cells are mediated by activation of signaling networks. Project Goals To evaluate the signaling networks involving transcription factor NF-kB and the mitochondrial antioxidant protein MnSOD. To determine if NF-kB is activated by low dose radiation in vivo. To determine if NF-kB activation is critical in the pathways that produce adaptive responses. Experimental Approach Cells transfected with NF-kB luciferase responder genes will be used to define a dose-response relationship for activation of the NF-kB gene. NF-kB

104

Human Heterochromatin Protein 1 Isoforms HP1Hs? and HP1Hs? Interfere with hTERT-Telomere Interactions and Correlate with Changes in Cell Growth and Response to Ionizing Radiation  

Science Journals Connector (OSTI)

...subsequently exposed to ionizing radiation (IR). The...a particular dose of radiation. The cells...to IR in the dose range of 0 to 8 Gy...treatment. Dose response curves...treated with ionizing radiation while growing...

Girdhar G. Sharma; Kyu-kye Hwang; Raj K. Pandita; Arun Gupta; Sonu Dhar; Julie Parenteau; Manjula Agarwal; Howard J. Worman; Raymund J. Wellinger; Tej K. Pandita

2003-11-01T23:59:59.000Z

105

Applied Radiation and Isotopes 57 (2002) 875882 Energy response of an imaging plate exposed to  

E-Print Network (OSTI)

, TN 37232-5671, USA b Ionizing Radiation Division, National Institute of Standard and Technology, 100 when exposed to ionizing radiation, store a latent image that can be read out with a red laser beta emitters such as P-32 and Sr- 90 due to the advantages of short range dose delivery and suitable

Tolk, Norman H.

106

Low Dose Radiation Research Program: Gregory A. Kimmel  

NLE Websites -- All DOE Office Websites (Extended Search)

Gregory A. Kimmel Gregory A. Kimmel Pacific Northwest National Laboratory Past Project A Novel Spatially Resolved Cell Irradiator to Study Bystander and Adaptive Responses to Low-LET Radiation. Technical Abstracts 2002 Workshop: Spatially Resolved Single Cell Irradiator to Study Bystander Responses to Low LET Radiation. Resat, M.S., Kimmel, G.A., Miller, J.H., McDonald, J.C., Murphy, M.K., Strom, D.J., Thrall, B.D., and Colson, S.D. 2001 Workshop: Spatially Resolved Single Cell Irradiator to Study Bystander Responses to Low LET Radiation. Resat, M.S., Kimmel, G.A., Miller, J.H., McDonald, J.C., Murphy, M.K., Strom, D.J., Thrall, B.D., Metting, N.F., and Colson, S.D 1999 Workshop: A Novel, Spatially Resolved Cell Irradiator to Study Bystander and Adaptive Responses to Low-LET Radiation.

107

Adaptability and human genetics.  

Science Journals Connector (OSTI)

...parts of the system follow logically...desiccating winds, and extreme solar radiation...inclusive population system, is a major...Chung, 1966). Hybrid studies are...with population systems, dynamic population...adaptive traits. Hybrid individuals...

W S Laughlin

1968-01-01T23:59:59.000Z

108

Adaptors for radiation detectors  

DOE Patents (OSTI)

Described herein are adaptors and other devices for radiation detectors that can be used to make accurate spectral measurements of both small and large bulk sources of radioactivity, such as building structures, soils, vessels, large equipment, and liquid bodies. Some exemplary devices comprise an adaptor for a radiation detector, wherein the adaptor can be configured to collimate radiation passing through the adapter from an external radiation source to the radiation detector and the adaptor can be configured to enclose a radiation source within the adapter to allow the radiation detector to measure radiation emitted from the enclosed radiation source.

Livesay, Ronald Jason

2014-04-22T23:59:59.000Z

109

The cytokinesis-blocked micronucleus assay: Dose estimation and inter-individual differences in the response to ?-radiation  

Science Journals Connector (OSTI)

Abstract Biological dosimetry plays an important role in case of a radiation accident or incident, either when it is the only way to estimate the dose or when it is used to complement physical dosimetry. A cytogenetic study was conducted in a group of 16 Portuguese individuals by use of the cytokinesis-blocked micronucleus (CBMN) assay. A doseresponse curve for micronuclei yield was established with a linear-quadratic model: Y=(0.01220.0010)+(0.02410.0023)D+(0.01930.0007)D2. Also, baseline values for the micronucleus formation in the 16 donors were analyzed, with results in close agreement with those from other laboratories. A validation experiment was carried out with three individuals. The real and the estimated doses obtained with the doseresponse curve were in very good agreement, allowing the use of the micronucleus doseresponse calibration curve in biological dosimetry for estimation of radiation dose in case of overexposure. The results obtained for the cytogenetic endpoints, studied in the same group of 16 individuals, were also analyzed as a function of age and gender. A higher inter-variability was observed for the higher dose points and differences in response were identified between genders, above 2Gy, for all endpoints.

A.C. Antunes; V. Martins; J. Cardoso; L. Santos; O. Monteiro Gil

2014-01-01T23:59:59.000Z

110

Adaptive sampler  

DOE Patents (OSTI)

An adaptive data compression device for compressing data having variable frequency content, including a plurality of digital filters for analyzing the content of the data over a plurality of frequency regions, a memory, and a control logic circuit for generating a variable rate memory clock corresponding to the analyzed frequency content of the data in the frequency region and for clocking the data into the memory in response to the variable rate memory clock.

Watson, Bobby L. (Idaho Falls, ID); Aeby, Ian (Fremont, CA)

1982-01-01T23:59:59.000Z

111

Adaptive sampler  

DOE Patents (OSTI)

An adaptive data compression device for compressing data is described. The device has a frequency content, including a plurality of digital filters for analyzing the content of the data over a plurality of frequency regions, a memory, and a control logic circuit for generating a variable rate memory clock corresponding to the analyzed frequency content of the data in the frequency region and for clocking the data into the memory in response to the variable rate memory clock.

Watson, B.L.; Aeby, I.

1980-08-26T23:59:59.000Z

112

The Circadian Rhythm, A Continuous Transcription-Translation Feedback Loop, Contributes to Low-Dose Radiation-Induced Radioadaptive Response  

NLE Websites -- All DOE Office Websites (Extended Search)

The Circadian Rhythm, A Continuous Transcription-Translation Feedback Loop, Contributes to Low-Dose Radiation-Induced Radioadaptive Response Aris Alexandrou and Jian Jian Li Department of Radiation Oncology, the University of California Davis, Sacramento, California, 95817 The initiation of the circadian rhythm field occurred when the Takahashi group defined a mutation in the mouse gene "Clock" and cloned the circadian locomotor output cycles kaput (Clock) in the mid- 1990's (1-3). Currently more than a dozen clock genes have been identified (3-4). Disruptions in the circadian rhythm via changes in environmental conditions, such as, diet, temperature, and night/day hours lead to the pathogenesis of a multitude of diseases, such as, cancer, diabetes mellitus,

113

A Functional Interaction of the C-Abl and Heat Shock Response Pathways in  

NLE Websites -- All DOE Office Websites (Extended Search)

Functional Interaction of the C-Abl and Heat Shock Response Pathways in Functional Interaction of the C-Abl and Heat Shock Response Pathways in Radio-Adaptive Response Hang Su & Zhi-Min Yuan University of Texas Health Science Center at San Antonio Abstract A functional interaction of the c-Abl and heat shock response pathways in radio-adaptive response Hang Su & Zhi-Min Yuan. Department of Radiation Oncology, UTHSCSA The radio-adaptive response, i.e. a low dose of radiation can protect cells and organisms from the effects of a subsequent higher dose, is a phenomenon that has been widely recognized. However, mechanisms underlying such radiation hormesis remain largely unclear. Our preliminary studies have uncovered a crucial role for the c-Abl tyrosine kinase as evidenced by that c-Abl-deficient cells exhibited a compromised

114

Molecular stress response in the CNS of mice after systemic exposureto interferon-alpha, ionizing radiation and ketamine  

SciTech Connect

We previously showed that the expression of troponin T1 (Tnnt 1) was induced in the central nervous system (CNS) of adultmice 30 min after treatment with ketamine, a glutamate N-methyl-D-aspartic acid (NMDA) receptor antagonist. We hypothesized that Tnnt 1 expression may be an early molecular biomarker of stress response in the CNS of mice. To further evaluate this hypothesis, we investigated the regional expression of Tnnt 1 in the mouse brain using RNA in situ hybridization 4 h after systemic exposure to interferon-a (IFN-a) and gamma ionizing radiation, both of which have be associated with wide ranges of neuropsychiatric complications. Adult B6C3F1 male mice were treated with either human IFN-a (a single i.p. injection at 1 x 105 IU/kg) or whole body gamma-radiation (10 cGy or 2 Gy). Patterns of Tnnt 1 transcript expression were compared in various CNS regions after IFN-a, radiation and ketamine treatments (previous study). Tnnt 1 expression was consistently induced in pyramidal neurons of cerebral cortex and hippocampus after all treatment regimens including 10 cGy of ionizing radiation. Regional expression of Tnnt 1 was induced in Purkinje cells of cerebellum after ionizing radiation and ketamine treatment; but not after IFN-a treatment. None of the three treatments induced Tnnt 1 expression in glial cells. The patterns of Tnnt 1 expression in pyramidal neurons of cerebral cortex andhippocampus, which are both known to play important roles in cognitive function, memory and emotion, suggest that the expression of Tnnt 1 may be an early molecular biomarker of induced CNS stress.

Lowe, Xiu R.; Marchetti, Francesco; Lu, Xiaochen; Wyrobek, Andrew J.

2009-03-03T23:59:59.000Z

115

Mammalian Tissue Response to Low Dose Ionizing Radiation: The Role of Oxidative Metabolism and Intercellular Communication  

SciTech Connect

The objective of the project was to elucidate the mechanisms underlying the biological effects of low dose/low dose rate ionizing radiation in organs/tissues of irradiated mice that differ in their susceptibility to ionizing radiation, and in human cells grown under conditions that mimic the natural in vivo environment. The focus was on the effects of sparsely ionizing cesium-137 gamma rays and the role of oxidative metabolism and intercellular communication in these effects. Four Specific Aims were proposed. The integrated outcome of the experiments performed to investigate these aims has been significant towards developing a scientific basis to more accurately estimate human health risks from exposures to low doses ionizing radiation. By understanding the biochemical and molecular changes induced by low dose radiation, several novel markers associated with mitochondrial functions were identified, which has opened new avenues to investigate metabolic processes that may be affected by such exposure. In particular, a sensitive biomarker that is differentially modulated by low and high dose gamma rays was discovered.

Azzam, Edouard I

2013-01-16T23:59:59.000Z

116

The Polyamine Catabolic Enzyme SAT1 Modulates Tumorigenesis and Radiation Response in GBM  

Science Journals Connector (OSTI)

...a polyamine acetyltransferase in deadly brain tumors contributes to their inherent radioresistance...is the most common and severe form of brain cancer. The median survival time of patients...radiation (IR), is overexpressed in brain tumors, and correlates with poor outcomes...

Adina Brett-Morris; Bradley M. Wright; Yuji Seo; Vinay Pasupuleti; Junran Zhang; Jun Lu; Raffaella Spina; Eli E. Bar; Maneesh Gujrati; Rebecca Schur; Zheng-Rong Lu; Scott M. Welford

2014-12-01T23:59:59.000Z

117

Differences in Brainstem Fiber Tract Response to Radiation: A Longitudinal Diffusion Tensor Imaging Study  

SciTech Connect

Purpose: To determine whether radiation-induced changes in white matter tracts are uniform across the brainstem. Methods and Materials: We analyzed serial diffusion tensor imaging data, acquired before radiation therapy and over 48 to 72 months of follow-up, from 42 pediatric patients (age 6-20 years) with medulloblastoma. FSL software (FMRIB, Oxford, UK) was used to calculate fractional anisotropy (FA) and axial, radial, and mean diffusivities. For a consistent identification of volumes of interest (VOIs), the parametric maps of each patient were transformed to a standard brain space (MNI152), on which we identified VOIs including corticospinal tract (CST), medial lemniscus (ML), transverse pontine fiber (TPF), and middle cerebellar peduncle (MCP) at the level of pons. Temporal changes of DTI parameters in VOIs were compared using a linear mixed effect model. Results: Radiation-induced white matter injury was marked by a decline in FA after treatment. The decline was often accompanied by decreased axial diffusivity, increased radial diffusivity, or both. This implied axonal damage and demyelination. We observed that the magnitude of the changes was not always uniform across substructures of the brainstem. Specifically, the changes in DTI parameters for TPF were more pronounced than in other regions (P<.001 for FA) despite similarities in the distribution of dose. We did not find a significant difference among CST, ML, and MCP in these patients (P>.093 for all parameters). Conclusions: Changes in the structural integrity of white matter tracts, assessed by DTI, were not uniform across the brainstem after radiation therapy. These results support a role for tract-based assessment in radiation treatment planning and determination of brainstem tolerance.

Uh, Jinsoo, E-mail: jinsoo.uh@stjude.org [Department of Radiological Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee (United States)] [Department of Radiological Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee (United States); Merchant, Thomas E. [Department of Radiological Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee (United States)] [Department of Radiological Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee (United States); Li, Yimei; Feng, Tianshu [Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee (United States)] [Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee (United States); Gajjar, Amar [Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee (United States)] [Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee (United States); Ogg, Robert J.; Hua, Chiaho [Department of Radiological Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee (United States)] [Department of Radiological Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee (United States)

2013-06-01T23:59:59.000Z

118

OPERATIONAL GUIDANCE FOR RADIATION EMERGENCY RESPONSE ORGANISATIONS IN EUROPE FOR USING BIODOSIMETRIC TOOLS DEVELOPED IN EU MULTIBIODOSE PROJECT  

Science Journals Connector (OSTI)

......Radiation Surveillance, Radiation and Nuclear Safety Authority, Helsinki...for most low-LET radiation qualities. THE MULTIBIODOSE SOFTWARE The Guidance briefly...K. Multibiodose Radiation Emergency Triage Categorization Software. Health Phys......

Alicja Jaworska; Elizabeth A. Ainsbury; Paola Fattibene; Carita Lindholm; Ursula Oestreicher; Kai Rothkamm; Horst Romm; Hubert Thierens; Francois Trompier; Philippe Voisin; Anne Vral; Clemens Woda; Andrzej Wojcik

2014-10-01T23:59:59.000Z

119

Threshold estimation from the linear dose-response model: Method and radiation data  

Science Journals Connector (OSTI)

The linear dose-response model is considered a conservative, nonthreshold relationship. This is based on a confusion between the sufficient condition (that is, zero slope at zero dose) and the necessary condit...

David J. Schaeffer; Konanur G. Janardan; Harold W. Kerster

1981-01-01T23:59:59.000Z

120

Effects of ionizing radiation on the response of certain photosensitive seeds to red light  

E-Print Network (OSTI)

and molecular oxygen. Studies of phosphate metabolism (Surrey and Gordon, 1962) and phosphorylation (Gordon and Surrey, 1961) indicate that energy transfer through phosphate esterification plays an important role and may be the key enzymatic reaction in red... spectrum promoting the germination of light-sensitive lettuce seed. Smithsonian Inst. Pubis. Misc. Collections 96: 1-8 ~ 11. Gordon, S. A. , and K. Surrey. 1961. Phosphorylation and red-spectrum photomorphogenesis. ~n Effects of ionizing radiations...

Richardson, Billy

2012-06-07T23:59:59.000Z

Note: This page contains sample records for the topic "radiation adaptive responses" from the National Library of EnergyBeta (NLEBeta).
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121

Estimation of isodose curves in radiation therapy and related response analysis  

E-Print Network (OSTI)

by a review of literature and the second by a computer program. Accompanying the literature review is a bibliography of interstitial and intracavitary radiation therapy dealing with radium and radon sources with emphasis on references dealing...- 2 active seed (usually radon or gold-198) could be made the proper strength to destroy only the tumor when placed in the center of the tumor, However, tumors are rarely or never truly spheroid and, in addition, economic considerations dictate...

Goodlett, James Campbell

2012-06-07T23:59:59.000Z

122

Dynamical and radiative response to the massive injection of aerosol from Kuwait oil burning fires  

SciTech Connect

The effects of the injection of large amount of soot comparable to that produced in the burning of oil wells in Kuwait were studied using a 2-D mesoscale model. During the three day numerical simulation the ground-atmosphere system appears to be strongly perturbed. A surface cooling is produced in the first two days above and downwind of the sources. The cooling, between -10 C over the desert and -0.5 C over the sea is dependent on the surface characteristics. The temperature decrease at the ground results in a stratified troposphere which inhibits convection and perturbs the normal diurnal variability of the boundary layer while the upper levels are driven by the radiative warming of the aerosol layer. In this region after few hours the simulation produces a warming of 0.8 C reaching a maximum of 6 C is after 60 hours. During the last 2 days of simulation the long wave radiation emitted by the low altitude atmospheric layers contribute to mitigate the surface cooling. A detailed discussion of the radiative and the dynamical interactions is given and it is shown that beside the specific interest in the short term effects these results may be useful to parameterize the smoke source for a General Circulation Model (GCM) simulation.

Ferretti, R.; Visconti, G. [Univ. L`Aquila (Italy)

1993-12-01T23:59:59.000Z

123

Proposed radiation hardened mobile vehicle for Chernobyl dismantlement and nuclear accident response  

SciTech Connect

Researchers are developing a radiation hardened, Telerobotic Dismantling System (TDS) to remediate the Chernobyl facility. To withstand the severe radiation fields, the robotic system, will rely on electrical motors, actuators, and relays proven in the Chernobyl power station. Due to its dust suppression characteristics and ability to cut arbitrary materials the authors propose using a water knife as the principle tool to slice up the large fuel containing masses. The front end of the robot will use a minimum number of moving parts by locating most of the susceptible and bulky components outside the work area. Hardened and shielded video cameras will be designed for remote control and viewing of the robotic functions. Operators will supervise and control robot movements based on feedback from a suite of sensory systems that would include vision systems, radiation detection and measurement systems and force reflection systems. A gripper will be instrumented with a variety of sensors (e.g. force, torque, or tactile), allowing varying debris surface properties to be grasped. The gripper will allow the operator to manipulate and segregate debris items without entering the radiologically and physically dangerous dismantlement operations area. The robots will initially size reduce the FCM`s to reduce the primary sources of the airborne radionuclides. The robot will then remove the high level waste for packaging or decontamination, and storage nearby.

Rowland, M.S.; Holliday, M.A. [Lawrence Livermore National Lab., CA (United States); Karpachov, J.A. [Scientific Inst. of Special Mechanical Problems, Kiev (Ukraine). Polytechnical Inst.; Ivanov, A. [Interbranch Scientific and Technical Center, Chernobyl (Ukraine)

1995-01-01T23:59:59.000Z

124

Association of Clinical Response and Long-term Outcome Among Patients With Biopsied Orbital Pseudotumor Receiving Modern Radiation Therapy  

SciTech Connect

Purpose: To retrospectively evaluate institutional outcomes for patients treated with modern radiation therapy (RT) for biopsied orbital pseudotumor (OP). Methods and Materials: Twenty patients (26 affected orbits) with OP were treated with RT between January 2002 and December 2011. All patients underwent biopsy with histopathologic exclusion of other disease processes. Sixteen patients (80%) were treated with intensity modulated RT, 3 (15%) with opposed lateral beams, and 1 (5%) with electrons. Median RT dose was 27 Gy (range 25.2-30.6 Gy). Response to RT was evaluated at 4 months post-RT. Partial response (PR) was defined as improvement in orbital symptoms without an increase in steroid dose. Complete response (CR) 1 and CR 2 were defined as complete resolution of orbital symptoms with reduction in steroid dose (CR 1) or complete tapering of steroids (CR 2). The median follow-up period was 18.6 months (range 4-81.6 months). Results: Seventeen patients (85%) demonstrated response to RT, with 7 (35%), 1 (5%), and 9 (45%) achieving a PR, CR 1, and CR 2, respectively. Of the 17 patients who had ?PR at 4 months post-RT, 6 (35%) experienced recurrence of symptoms. Age (>46 years vs ?46 years, P=.04) and clinical response to RT (CR 2 vs CR 1/PR, P=.05) were significantly associated with pseudotumor recurrence. Long-term complications were seen in 7 patients (35%), including 4 with cataract formation, 1 with chronic dry eye, 1 with enophthalmos, and 1 with keratopathy. Conclusions: RT is an effective treatment for improving symptoms and tapering steroids in patients with a biopsy supported diagnosis of OP. Older age and complete response to RT were associated with a significantly reduced probability of symptom recurrence. The observed late complications may be related to RT, chronic use of steroids/immunosuppressants, medical comorbidities, or combination of factors.

Prabhu, Roshan S., E-mail: rprabhu@emory.edu [Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia (United States); Kandula, Shravan; Liebman, Lang [Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia (United States)] [Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia (United States); Wojno, Ted H.; Hayek, Brent [Division of Oculoplastics, Orbital and Cosmetic Surgery, Emory University, Atlanta, Georgia (United States)] [Division of Oculoplastics, Orbital and Cosmetic Surgery, Emory University, Atlanta, Georgia (United States); Hall, William A.; Shu, Hui-Kuo; Crocker, Ian [Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia (United States)] [Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia (United States)

2013-03-01T23:59:59.000Z

125

Mobilization of Circulating Vascular Progenitors in Cancer Patients Receiving External Beam Radiation in Response to Tissue Injury  

SciTech Connect

Purpose: Endothelial-like vascular progenitor cells (VPCs) are associated with the repair of ischemic tissue injury in several clinical settings. Because the endothelium is a principal target of radiation injury, VPCs may be important in limiting toxicity associated with radiotherapy (RT) in patients with cancer. Methods and Materials: We studied 30 patients undergoing RT for skin cancer (n = 5), head-and-neck cancer (n = 15), and prostate cancer (n = 10) prospectively, representing a wide range of irradiated mucosal volumes. Vascular progenitor cell levels were enumerated from peripheral blood at baseline, midway through RT, at the end of treatment, and 4 weeks after radiation. Acute toxicity was graded at each time point by use of the National Cancer Institute's Common Toxicity Criteria, version 3.0. Results: Significant increases in the proportion of CD34{sup +}/CD133{sup +} VPCs were observed after completion of RT, from 0.012% at baseline to 0.048% (p = 0.029), and the increase in this subpopulation was most marked in patients with Grade 2 peak toxicity or greater after RT (p = 0.034). Similarly, CD34{sup +}/vascular endothelial growth factor receptor 2-positive VPCs were increased after the completion of radiation therapy in comparison to baseline (from 0.014% to 0.027%, p = 0.043), and there was a trend toward greater mobilization in patients with more significant toxicity (p = 0.08). The mobilization of CD34{sup +} hematopoietic stem cells did not increase after treatment (p = 0.58), and there was no relationship with toxicity. Conclusions: We suggest that VPCs may play an important role in reducing radiation-induced tissue damage. Interventions that increase baseline VPC levels or enhance their mobilization and recruitment in response to RT may prove useful in facilitating more rapid and complete tissue healing.

Allan, David S. [Ottawa Health Research Institute, Regenerative Medicine Program, Ottawa, Ontario (Canada)], E-mail: daallan@ohri.ca; Morgan, Scott C. [Ottawa Hospital Cancer Centre, Ottawa, Ontario (Canada); Division of Radiation Oncology, University of Ottawa, Ottawa, Ontario (Canada); Birch, Paul E.; Yang, Lin; Halpenny, Michael J. [Stem Cell Processing Laboratory, Canadian Blood Services, Ottawa, Ontario (Canada); Gunanayagam, Angelo; Li Yuhua [Ottawa Health Research Institute, Regenerative Medicine Program, Ottawa, Ontario (Canada); Eapen, Libni [Ottawa Hospital Cancer Centre, Ottawa, Ontario (Canada); Division of Radiation Oncology, University of Ottawa, Ottawa, Ontario (Canada)

2009-09-01T23:59:59.000Z

126

Construction of dose response calibration curves for dicentrics and micronuclei for X radiation in a Serbian population  

Science Journals Connector (OSTI)

Abstract Biological dosimetry using chromosome damage biomarkers is a valuable dose assessment method in cases of radiation overexposure with or without physical dosimetry data. In order to estimate dose by biodosimetry, any biological dosimetry service have to have its own dose response calibration curve. This paper reveals the results obtained after irradiation of blood samples from fourteen healthy male and female volunteers in order to establish biodosimetry in Serbia and produce dose response calibration curves for dicentrics and micronuclei. Taking into account pooled data from all the donors, the resultant fitted curve for dicentrics is: Ydic=0.0009 (0.0003)+0.0421 (0.0042)נD+0.0602 (0.0022)נD2; and for micronuclei: Ymn=0.0104 (0.0015)+0.0824 (0.0050)נD+0.0189 (0.0017)נD2. Following establishment of the dose response curve, a validation experiment was carried out with four blood samples. Applied and estimated doses were in good agreement. On this basis, the results reported here give us confidence to apply both calibration curves for future biological dosimetry requirements in Serbia.

J. Pajic; B. Rakic; D. Jovicic; A. Milovanovic

2014-01-01T23:59:59.000Z

127

Low Dose Radiation Research Program: Checkpoint Responses and Repair of a  

NLE Websites -- All DOE Office Websites (Extended Search)

Checkpoint Responses and Repair of a Broken Chromosome in Budding Checkpoint Responses and Repair of a Broken Chromosome in Budding Yeast. Authors: André Walther, Mreshwar B. Vaze, Anna Malkova, Grzegorz Ira, Xuan Wang, Jung-Ae Kim, Neal Sugawara, James E. Haber Brandeis University, Waltham, Massachusetts We have studied how yeast cells respond to the creation of a single double-strand break (DSB) by using a site-specific endonuclease to create one (or more) DSBs. In collaboration with R. Schroff, M. Licheten and W. Bonner (NIH) we have shown that a single DSB rapidly becomes associated with histone H2AX-phosphorylation (y-H2AX) covering a distance of about 25 kb on either side of the DSB. The drop-off in phosphorylation is not attributable to specific boundary sequences. y-H2AX can be phosphorylated by either ATR (Mec1) or ATM (Tel1) protein kinases. A mutation that removes

128

Effect of radiation on the response of dental pulp to operative and endodontic procedures: an experimental study  

SciTech Connect

Thirty-six 56-day-old male Sprague-Dawley albino rats served as two groups of experimental animals. Group 1 was irradiated with 400 rads delivered as total-body radiation from a cesium source. Group 2 served as the control group and was not irradiated. Three weeks later, the dental microscope was used to facilitate various dental procedures in both groups of animals (cavity preparation filled with zinc oxide-eugenol, pulp exposure capped with zinc oxide-eugenol, and pulp exposure left open). Two animals for each procedure from Groups 1 and 2 were killed at time intervals of 2, 4, and 8 weeks. The results showed that (1) radiation at this dose resulted in a depression of the normal response of the dental pulp to the trauma and infection induced by pulpal exposure, (2) there were no pathologic changes in the untreated molars of the irradiated animals, and (3) the use of the dental microscope greatly facilitated cavity preparation in the molars of rats.

Fawzi, M.I.; Shklar, G.; Krakow, A.A.

1985-04-01T23:59:59.000Z

129

Radiation Control (Virginia)  

Energy.gov (U.S. Department of Energy (DOE))

The Department of Health is responsible for regulating radiation and radioactive materials in the Commonwealth of Virginia. Although the Department's Radiation Control Program primarily focuses on...

130

Impulsive cylindrical gravitational wave: one possible radiative form emitted from cosmic strings and corresponding electromagnetic response  

E-Print Network (OSTI)

The cosmic strings(CSs) may be one important source of gravitational waves(GWs), and it has been intensively studied due to its special properties such as the cylindrical symmetry. The CSs would generate not only usual continuous GW, but also impulsive GW that brings more concentrated energy and consists of different GW components broadly covering low-, intermediate- and high-frequency bands simultaneously. These features might underlie interesting electromagnetic(EM) response to these GWs generated by the CSs. In this paper, with novel results and effects, we firstly calculate the analytical solutions of perturbed EM fields caused by interaction between impulsive cylindrical GWs (would be one of possible forms emitted from CSs) and background celestial high magnetic fields or widespread cosmological background magnetic fields, by using rigorous Einstein - Rosen metric. Results show: perturbed EM fields are also in the impulsive form accordant to the GW pulse, and asymptotic behaviors of the perturbed EM fields are fully consistent with the asymptotic behaviors of the energy density, energy flux density and Riemann curvature tensor of corresponding impulsive cylindrical GWs. The analytical solutions naturally give rise to the accumulation effect which is proportional to the term of distance^1/2, and based on it, we for the first time predict potentially observable effects in region of the Earth caused by the EM response to GWs from the CSs.

H. Wen; F. Y. Li; Z. Y. Fang; A. Beckwith

2014-05-04T23:59:59.000Z

131

Low Dose Radiation Research Program: Chaun-Yuan Li  

NLE Websites -- All DOE Office Websites (Extended Search)

Chaun-Yuan Li Chaun-Yuan Li Radiation Biology Research, Duke University Medical Center Funded Projects Molecular Characterization of the Role of SOD Genes in Mammalian Cellular Response to Low Dose Ionizing, abstract, description. Technical Abstracts 2006 Workshop: The Roles of Superoxide Dismutage (SOD) in Low Dose Radiation Induced Adaptive Response Yang, Z., Chuang, E., Batinic-Haberle, I., and Li, C.-Y. 2005 Workshop: Molecular Characterization of the Roles of SOD Genes in Mammalian Cellular Response to Low Dose Radiation Li, C.-Y., Guo, Z., Yang, Z., and Chuang, E. 2003 Workshop: Molecular Characterization of the Roles of SOD Genes in Mammalian Cellular Response to Low Dose Radiation Li, C.-Y. and Chuang, E. Publications Li, F., Sonveaux, P., Rabbani, Z.N., Liu, S., Yan, B., Huang, Q.,

132

Low Dose Radiation Research Program: William F. Morgan  

NLE Websites -- All DOE Office Websites (Extended Search)

William F. Morgan William F. Morgan Pacific Northwest National Laboratory PO Box 999 Richland, Washington About this Project Projects Using a Low LET Electron Microbeam to Investigate Non-Targeted Effects of Low Dose Radiation. Optimizing the Scientific, Regulatory, and Societal Impact of the DOE Low Dose Radiation Research Program A Mechanistic Study of the Radiation Quality Dependence of Bystander Effects in Human Cells. Genetic Factors Affecting Susceptibility to Low-Dose Radiation Mechanisms of Adaptive Responses and Genomic Instability Induced by Low Dose/ Low Dose Rate Radiation Technical Abstracts 2006 Workshop: Using a Low-LET Electron Microbeam to Investigate Non-Targeted Effects of Low Dose Radiation Sowa, M.B., Goetz, W., Baulch, J., and Morgan, W.F. Genetic Factors Affecting Susceptibility to Low-Dose Radiation

133

Quantifying murine bone marrow and blood radiation dose response following 18F-FDG PET with DNA damage biomarkers  

Science Journals Connector (OSTI)

Abstract The purpose of this study was to quantify the poorly understood radiation doses to murine bone marrow and blood from whole-body fluorine 18 (18F)-fluorodeoxyglucose (FDG) positron emission tomography (PET), by using specific biomarkers and comparing with whole body external low dose exposures. Groups of 35 mice were randomly assigned to 10 groups, each receiving either a different activity of 18F-FDG: 037MBq or whole body irradiated with corresponding doses of 0300mGy X-rays. Blood samples were collected at 24h and at 43h for reticulocyte micronucleus assays and QPCR analysis of gene expression in peripheral blood leukocytes. Blood and bone marrow dose estimates were calculated from injected activities of 18F-FDG and were based on a recommended ICRP model. Doses to the bone marrow corresponding to 33.43mGy and above for internal 18F-FDG exposure and to 25mGy and above for external X-ray exposure, showed significant increases in radiation-induced MN-RET formation relative to controls (Pdoseresponses at 24h for Bbc3 and Cdkn1 were similar for 18F-FDG and X-ray exposures, with significant modifications occurring for doses over 300mGy for Bbc3 and at the lower dose of 150mGy for Cdkn1a. Both leucocyte gene expression and quantification of MN-RET are highly sensitive biomarkers for reliable estimation of the low doses delivered in vivo to, respectively, blood and bone marrow, following 18F-FDG PET.

Grainne Manning; Kristina Taylor; Paul Finnon; Jennifer A. Lemon; Douglas R. Boreham; Christophe Badie

2014-01-01T23:59:59.000Z

134

Bacterial stress response to environmental radiation relating to the Fukushima radiation discharge event, Japan: Will environmental bacteria alter their antibiotic susceptibility profile?  

Science Journals Connector (OSTI)

Antibiotic resistance in clinical pathogens in humans may be traced back to resistance mechanisms in environmental bacteria and any factors, which are likely to alter (upregulate) resistance in environmental organisms, is of potential and eventual consequence to human pathogens. Furthermore, sublethal doses of gamma radiation to environmental organisms may cause sublethal stress and a selective pressure, which may lead to mutational events that alter the bacterium's susceptibility profile. A gamma (?) radiation simulation experiment was performed to emulate the exposure of four environmental bacteria, including Listeria innocua, Bacillus subtilis, E. coli and Pseudomonas aeruginosa, to levels of radiation in and around Fukushima, Japan, equating to 1, 10 and 100 years equivalence exposure. Alteration to susceptibility to 14 antibiotics was measured as the primary endpoint. There was no significant alteration in the susceptibility of the Gram-positive organisms, whereas both Gram-negative organisms became slightly more susceptible to the antibiotics tested over time. These data indicate that such radiation exposure will not increase the antibiotic resistance profile of these organisms and hence not add to the global public health burden of increased antibiotic resistance in human bacterial pathogens.

Shigeyuki Nakanishi; John E. Moore; Motoo Matsuda; Colin E. Goldsmith; Wilson A. Coulter; Juluri R. Rao

2012-01-01T23:59:59.000Z

135

p85? Acts as a Novel Signal Transducer for Mediation of Cellular Apoptotic Response to UV Radiation  

Science Journals Connector (OSTI)

...mediation of type B UV (UVB) radiation-induced cell death. This...University School of Medicine, Japan) and described previously...University of Tokyo, Tokyo, Japan) and were described in a previous...cells were then exposed to UVB radiation 36 h after infection with the...

Lun Song; Jingxia Li; Jianping Ye; Gang Yu; Jin Ding; Dongyun Zhang; Weiming Ouyang; Zigang Dong; Sung O. Kim; Chuanshu Huang

2007-01-22T23:59:59.000Z

136

Response of natural phytoplankton assemblages to solar ultraviolet radiation (UV-B) in the coastal water, Japan  

Science Journals Connector (OSTI)

Variability in the effect of solar ultraviolet radiation (UV-B) on primary productivity of ... water off Manazuru Harbor, Sagami Bay, central Japan for two full years during the period...13C method. Size distribu...

Takashi Sugawara; K. Hamasaki; T. Toda; T. Kikuchi; Satoru Taguchi

2003-02-01T23:59:59.000Z

137

Response of the NCAR Community Climate Model to the Radiative Forcing by the Naturally Occurring Tropospheric Aerosol  

Science Journals Connector (OSTI)

We insert the effect of naturally occurring tropospheric aerosols on solar radiation into the NCAR Community Climate Model (CCM). The effect of the aerosol depends on concentration and type (continental, maritime), surface albedo, solar zenith ...

James A. Coakley Jr.; Robert D. Cess

1985-08-01T23:59:59.000Z

138

Florida Radiation Protection Act (Florida)  

Energy.gov (U.S. Department of Energy (DOE))

The Department of Public Health is responsible for administering a statewide radiation protection program. The program is designed to permit development and utilization of sources of radiation for...

139

Simulation of Infrared Laser Heating of Silica Using Heat Conduction and Multifrequency Radiation Diffusion Equations Adapted for Homogeneous Refractive Lossy Media  

SciTech Connect

Localized, transient heating of materials using micro-scale, highly absorbing laser light has been used in many industries to anneal, melt and ablate material with high precision. Accurate modeling of the relative contributions of conductive, convective and radiative losses as a function of laser parameters is essential to optimizing micro-scale laser processing of materials. In bulk semi-transparent materials such as silicate glass melts, radiation transport is known to play a significantly larger role as the temperature increases. Conventionally, radiation is treated in the frequency-averaged diffusive limit (Rosseland approximation). However, the role and proper treatment of radiative processes under rapidly heated, high thermal gradient conditions, often created through laser-matter interactions, is at present not clear. Starting from the radiation transport equation for homogeneous, refractive lossy media, they derive the corresponding time-dependent multi-frequency diffusion equations. Zeroth and first moments of the transport equation couple the energy density, flux and pressure tensor. The system is closed by neglecting the temporal derivative of the flux and replacing the pressure tensor by its diagonal analogue. The radiation equations are coupled to a diffusion equation for the matter temperature. They are interested in modeling infrared laser heating of silica over sub-millimeter length scales, and at possibly rapid rates. Hence, in contrast to related work, they retain the temporal derivative of the radiation field. They derive boundary conditions at a planar air-silica interface taking account of reflectivities obtained from the Fresnel relations that include absorption. The effect of a temperature-dependent absorption index is explored through construction of a multi-phonon dielectric function that includes mode dispersion. The spectral dimension is discretized into a finite number of intervals yielding a system of multigroup diffusion equations. Simulations are presented. To demonstrate the bulk heat loss due to radiation and the effect of the radiation's temporal derivative, they model cooling of a silica slab, initially at 2500 K, for 10 s. Retaining the derivative enables correctly modeling the loss of photons initially present in the slab. Other simulations model irradiating silica discs (of approximately 5 mm radii and thickness) with a CO2 laser: {lambda} = 10.59 and 4.6 um, Gaussian profile, r{sub 0} = 0.5 mm for 1/e decay. By surrounding the disks in room-temperature air, they make use of the boundary conditions described above.

Shestakov, A I; Matthews, M J; Vignes, R M; Stolken, J S

2010-10-28T23:59:59.000Z

140

UV light-induced survival response in a highly radiation-resistant isolate of the Moraxella-Acinetobacter group.  

Science Journals Connector (OSTI)

...dose. This response was inhibited...ofchloramphenicol. Frequencies of mutation...the inducible response ofisolate 4...affect the frequency of mutation...extended cold storage. Iftrue...International Atomic Energy Agency, Vien...LIGHT-INDUCED SURVIVAL RESPONSE IN BACTERIA...and length of storage on the microbi...

L C Keller; T L Thompson; R B Maxcy

1982-02-01T23:59:59.000Z

Note: This page contains sample records for the topic "radiation adaptive responses" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


141

The Tropical Response to Extratropical Thermal Forcing in an Idealized GCM: The Importance of Radiative Feedbacks and Convective Parameterization  

E-Print Network (OSTI)

) atmospheric energy transport per unit mass transport] of the model tropics converts the energy flux change 25% between the imposed oceanic flux and the resulting response in the atmospheric energy transportThe Tropical Response to Extratropical Thermal Forcing in an Idealized GCM: The Importance

Miami, University of

142

The Influence of Cloud Microphysics and Radiation on the Response of Water Vapor and Clouds to Climate Change  

SciTech Connect

Uncertainties in representing the atmospheric water cycle are major obstacles to the accurate prediction of future climate. This project focused on addressing some of these uncertainties by implementing new physics for convection and radiation into the NCAR Community Atmosphere Model (CAM). To better understand and eventually better represent these processes in this major national climate model, we modified CAM3.5 to use the convection and cloud schemes developed by the Massachusetts Institute of Technology (MIT) and the RRTMG rapid radiation code for global climate models developed by Atmospheric and Environmental Research, Inc. (AER). The impact of the new physics on the CAM3.5 simulation of convection on diurnal and intra-seasonal scales, on intra-seasonal oscillations and on the distribution of water vapor has been investigated. In addition, the MIT and AER physics packages have been incorporated and tested in combination within the Weather Research and Forecasting (WRF) regional forecast model for the purpose of evaluating and improving convective and radiative processes on time scales appropriate to weather simulations. It has been found that the application of the AER radiation and MIT convection produces significant improvements in the modeled diurnal cycle of convection, especially over land, in the NCAR climate model. However, both the standard CAM3.5 and the modified CAM3.5 with the new physics are unable to capture the proper spectrum and propagating characteristics of dynamical intra-seasonal oscillations such as the Madden-Julian Oscillation. In addition, it has been shown that the new physics methods modify, but do not substantially improve, the distribution of upper tropospheric water vapor in CAM as established through the comparison of modeled and observed satellite radiances. This suggests that continuing regional discrepancies in water vapor amounts in the climate model may not be solely related to convective or radiative processes. The major results of this project have been described in more detail in a journal article titled ??The Impacts of AER Radiation and MIT Convection on the Water Cycle Simulated by CAM3.5? that will be submitted for publication during Fall 2010.

Emanuel, Kerry; Iacono, Michael J.

2010-11-11T23:59:59.000Z

143

DCE-MRI defined subvolumes of a brain metastatic lesion by principle component analysis and fuzzy-c-means clustering for response assessment of radiation therapy  

SciTech Connect

Purpose: To develop a pharmacokinetic modelfree framework to analyze the dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) data for assessment of response of brain metastases to radiation therapy. Methods: Twenty patients with 45 analyzable brain metastases had MRI scans prior to whole brain radiation therapy (WBRT) and at the end of the 2-week therapy. The volumetric DCE images covering the whole brain were acquired on a 3T scanner with approximately 5 s temporal resolution and a total scan time of about 3 min. DCE curves from all voxels of the 45 brain metastases were normalized and then temporally aligned. A DCE matrix that is constructed from the aligned DCE curves of all voxels of the 45 lesions obtained prior to WBRT is processed by principal component analysis to generate the principal components (PCs). Then, the projection coefficient maps prior to and at the end of WBRT are created for each lesion. Next, a pattern recognition technique, based upon fuzzy-c-means clustering, is used to delineate the tumor subvolumes relating to the value of the significant projection coefficients. The relationship between changes in different tumor subvolumes and treatment response was evaluated to differentiate responsive from stable and progressive tumors. Performance of the PC-defined tumor subvolume was also evaluated by receiver operating characteristic (ROC) analysis in prediction of nonresponsive lesions and compared with physiological-defined tumor subvolumes. Results: The projection coefficient maps of the first three PCs contain almost all response-related information in DCE curves of brain metastases. The first projection coefficient, related to the area under DCE curves, is the major component to determine response while the third one has a complimentary role. In ROC analysis, the area under curve of 0.88 0.05 and 0.86 0.06 were achieved for the PC-defined and physiological-defined tumor subvolume in response assessment. Conclusions: The PC-defined subvolume of a brain metastasis could predict tumor response to therapy similar to the physiological-defined one, while the former is determined more rapidly for clinical decision-making support.

Farjam, Reza; Tsien, Christina I.; Lawrence, Theodore S. [Department of Radiation Oncology, University of Michigan, 1500 East Medical Center Drive, SPC 5010, Ann Arbor, Michigan 48109-5010 (United States)] [Department of Radiation Oncology, University of Michigan, 1500 East Medical Center Drive, SPC 5010, Ann Arbor, Michigan 48109-5010 (United States); Cao, Yue, E-mail: yuecao@umich.edu [Department of Radiation Oncology, University of Michigan, 1500 East Medical Center Drive, SPC 5010, Ann Arbor, Michigan 48109-5010 (United States) [Department of Radiation Oncology, University of Michigan, 1500 East Medical Center Drive, SPC 5010, Ann Arbor, Michigan 48109-5010 (United States); Department of Radiology, University of Michigan, 1500 East Medical Center Drive, Med Inn Building C478, Ann Arbor, Michigan 48109-5842 (United States); Department of Biomedical Engineering, University of Michigan, 2200 Bonisteel Boulevard, Ann Arbor, Michigan 48109-2099 (United States)

2014-01-15T23:59:59.000Z

144

Collaborative Research: The Influence of Cloud Microphysics and Radiation on the Response of Water Vapor and Clouds to Climate Change  

SciTech Connect

Uncertainties in representing the atmospheric water cycle are major obstacles to an accurate prediction of future climate. This project focused on addressing some of these uncertainties by implementing new physics for convection and radiation into the NCAR climate model. To better understand and eventually better represent these processes, we modified CAM3.5 to use the convection and cloud schemes developed by the Massachusetts Institute of Technology (MIT) and the RRTMG rapid radiation code for global models developed by Atmospheric and Environmental Research, Inc. (AER). The impact of the new physics on the CAM3.5 simulation of convection on diurnal and intra-seasonal scales, intra-seasonal oscillations and the distribution of water vapor has been investigated. The effect of the MIT and AER physics also has been tested in the Weather Research and Forecasting (WRF) regional forecast model. It has been found that the application of the AER radiation and MIT convection produces significant improvements in the modeled diurnal cycle of convection, especially over land, in the NCAR climate model. However, both the standard CAM3.5 (hereinafter STD) and the modified CAM3.5 with the new physics (hereinafter MOD) are still unable to capture the proper spectrum and propagating characteristics of the intra-seasonal oscillations (ISOs). The new physics methods modify, but do not substantially improve, the distribution of upper tropospheric water vapor relative to satellite measurements.

Dr. Kerry Emanuel; Michael J. Iacono

2011-06-28T23:59:59.000Z

145

Development and adaptation of conduction and radiation heat-transfer computer codes for the CFTL. [Core Flow Test Loop; RODCON; HOTTEL  

SciTech Connect

RODCON and HOTTEL are two computational methods used to calculate thermal and radiation heat transfer for the Core Flow Test Loop (CFTL) analysis efforts. RODCON was developed at ORNL to calculate the internal temperature distribution of the fuel rod simulator (FRS) for the CFTL. RODCON solves the time-dependent heat transfer equation in two-dimensional (R angle) cylindrical coordinates at an axial plane with user-specified radial material zones and time- and position-variant surface conditions at the FRS periphery. Symmetry of the FRS periphery boundary conditions is not necessary. The governing elliptic, partial differential heat equation is cast into a fully implicit, finite-difference form by approximating the derivatives with a forward-differencing scheme with variable mesh spacing. The heat conduction path is circumferentially complete, and the potential mathematical problem at the rod center can be effectively ignored. HOTTEL is a revision of an algorithm developed by C.B. Baxi at the General Atomic Company (GAC) to be used in calculating radiation heat transfer in a rod bundle enclosed in a hexagonal duct. HOTTEL uses geometric view factors, surface emissivities, and surface areas to calculate the gray-body or composite view factors in an enclosure having multiple reflections in a nonparticipating medium.

Conklin, J.C.

1981-08-01T23:59:59.000Z

146

Adaptation Plan  

E-Print Network (OSTI)

Environment ? Natural Environment ? People FIVE STRATEGIES Copyright 2011, City of Chicago ADAPTATION ESL-KT-11-11-16 9 CCAP Adaptation Evolution 2007 2008 2009 2010 ? Understood the climate science: Assess climate impacts ? Assessed economic... E xi st in g Tr un k Existing on Rogers Rogers Ave CIP Stormwater management: Chicago?s comprehensive sewer model Climate impacts Example actions to prepare the built environment Copyright 2011, City of Chicago ESL-KT-11-11-16 13 CCAP...

Durnbaugh, A.

2011-01-01T23:59:59.000Z

147

Adaptive constructive processes 1 Running head: Adaptive constructive processes  

E-Print Network (OSTI)

to a current environmental demand when automatic, learned responses are not elicited. Bartlett argued further of Psychology Harvard University Cambridge, Massachusetts 02138 phone: (617) 495-3856 fax: (617) 496-3122 e to be operating in any well-adapted organic response (1932, p. 201)". He further emphasized the importance of "the

Schacter, Daniel

148

Adaptive sequential controller  

DOE Patents (OSTI)

An adaptive sequential controller (50/50') for controlling a circuit breaker (52) or other switching device to substantially eliminate transients on a distribution line caused by closing and opening the circuit breaker. The device adaptively compensates for changes in the response time of the circuit breaker due to aging and environmental effects. A potential transformer (70) provides a reference signal corresponding to the zero crossing of the voltage waveform, and a phase shift comparator circuit (96) compares the reference signal to the time at which any transient was produced when the circuit breaker closed, producing a signal indicative of the adaptive adjustment that should be made. Similarly, in controlling the opening of the circuit breaker, a current transformer (88) provides a reference signal that is compared against the time at which any transient is detected when the circuit breaker last opened. An adaptive adjustment circuit (102) produces a compensation time that is appropriately modified to account for changes in the circuit breaker response, including the effect of ambient conditions and aging. When next opened or closed, the circuit breaker is activated at an appropriately compensated time, so that it closes when the voltage crosses zero and opens when the current crosses zero, minimizing any transients on the distribution line. Phase angle can be used to control the opening of the circuit breaker relative to the reference signal provided by the potential transformer.

El-Sharkawi, Mohamed A. (Renton, WA); Xing, Jian (Seattle, WA); Butler, Nicholas G. (Newberg, OR); Rodriguez, Alonso (Pasadena, CA)

1994-01-01T23:59:59.000Z

149

Low Dose Radiation Research Program: Jian Jian Li  

NLE Websites -- All DOE Office Websites (Extended Search)

Jian Jian Li Jian Jian Li School of Health Sciences, Purdue University Newly Funded Projects Regulation of NF-kB and Mn SOD in Low Dose Radiation-Induced Adaptive Responses in Mouse and Human Skin Cells, abstract, description. Technical Abstracts 2006 Workshops: NF-kB Mediated Signaling Network in Low Dose X-Ray Induced Adaptive Protection on Mouse and Human Skin Epithelial Cells Ahmed, K.M., Fan, M., Spitz, and Li, J.J. 2005 Workshops: Adaptive Response of Mouse Skin Epithelial Cells to Low Dose Ionizing Radiation: Induction of NF-κB, MnSOD, 14-3-3ζ and Cyclin B1. Li, J.J., Ahmed, K.M., Fan, M., Dong, S., Spitz, D.R., and Yu, C.-R. 2003 Workshops: Gene Expression Profiles of Human Skin Keratinocytes Exposed to Acute and Chronic Ionizing Radiation Li, J.J., Ozeki, M., Wang, T., Tamae, D., Nelson, D., Wyrobek, A., and

150

Intensification of biodiesel production from waste goat tallow using infrared radiation: Process evaluation through response surface methodology and artificial neural network  

Science Journals Connector (OSTI)

Abstract For the first time, an efficient simultaneous trans/esterification process for biodiesel synthesis from waste goat tallow with considerable free fatty acids (FFAs) content has been explored employing an infrared radiation assisted reactor (IRAR). The impacts of methanol to tallow molar ratio, IRAR temperature and H2SO4 concentration on goat tallow conversion were evaluated by response surface methodology (RSM). Under optimal conditions, 96.7% FFA conversion was achieved within 2.5h at 59.93wt.% H2SO4, 69.97C IRAR temperature and 31.88:1 methanol to tallow molar ratio. The experimental results were also modeled using artificial neural network (ANN) and marginal improvement in modeling efficiency was observed in comparison with RSM. The infrared radiation strategy could significantly accelerate the conversion process as demonstrated through a substantial reduction in reaction time compared to conventionally heated reactor while providing appreciably high biodiesel yield. Moreover, the in situ water removal using silica-gel adsorbent could also facilitate achieving higher FFA conversion to fatty acid methyl ester (FAME). Owing to the occurrence of simultaneous transesterification of triglycerides present in goat tallow, overall 98.5wt.% FAME content was determined at optimal conditions in the product biodiesel which conformed to ASTM and EN biodiesel specifications.

R. Chakraborty; H. Sahu

2014-01-01T23:59:59.000Z

151

A study to determine statistically and empirically the influence of solar radiation on physiological responses of dairy cattle  

E-Print Network (OSTI)

variables as cowes of heat distress. Statistical oatinatos vore ealculatod separa~ on shade noasurenonts and on suu neasurenents on a vithin-aninal and vitbin- genetio group basis. In all statistioal procedures, we vas nado of the International Business... by days Table l. Analysis of varianoe of body tenporaturo response in 1955. Degrees of Suu of Total Iooations Conatio groups 1 ~946. 74 392. 48 392. 48aa 23. 30 43 ?gled Looations x groups Looations x days Groups x days Error Locations x...

Williams, James Stanley

2012-06-07T23:59:59.000Z

152

Low Dose Radiation Research Program: Wide Expression of LLIR and the  

NLE Websites -- All DOE Office Websites (Extended Search)

Wide Expression of LLIR and the Biological Consequences Wide Expression of LLIR and the Biological Consequences David J. Chen Lawrence Berkeley National Laboratory Why This Project It is known that changes in gene expression alter biological effects. It is necessary to identify the specific genes that demonstrate altered expression after exposure to low doses of ionizing radiation and to determine pathways involved in DNA damage recognition, signaling, and repair that are associated with radiation-induced adaptive and bystander effects. Project Goals Identification of genes whose transcription is regulated in response to low levels of ionizing radiation Identification of the genes and communication pathways that control these responses to low dose radiation Identification of the cellular and molecular targets that influence

153

Urban climate resilience : a global assessment of city adaptation plans  

E-Print Network (OSTI)

As policy makers accept climate change as an irrefutable threat, adaptation planning has emerged as a necessary action for countries, states, and municipalities. This thesis explores adaptive responses to climate change ...

Katich, Kristina Noel

2009-01-01T23:59:59.000Z

154

Radiation source rate estimation through data assimilation of gamma dose rate measurements for operational nuclear emergency response systems  

Science Journals Connector (OSTI)

This paper presents an evaluation of an innovative data assimilation method that has been recently developed in NCSR Demokritos for estimating an unknown emission rate of radionuclides in the atmosphere, with real-scale experimental data. The efficient algorithm is based on the assimilation of gamma dose rate measured data in the Lagrangian atmospheric dispersion model DIPCOT and uses variational principles. The DIPCOT model is used in the framework of the nuclear emergency response system (ERS) RODOS. The evaluation is performed by computational simulations of dispersion of Ar-41 that was emitted routinely by the Australian Nuclear Science and Technology Organisation's (ANSTO) previous research reactor, HIFAR, located in Sydney, Australia. In this paper the algorithm is evaluated against a more complicated case than the others used in previous studies: there was only one monitoring station available each day and the site topography is characterised as moderately complex. Overall the estimated release rate approaches the real one to a very satisfactory degree as revealed by the statistical indicators of errors.

Vasiliki Tsiouri; Spyros Andronopoulos; Ivan Kovalets; Leisa L. Dyer; John G. Bartzis

2012-01-01T23:59:59.000Z

155

REGULATORY MECHANISMS OF SLC39A4 (ZIP4) AND SLC39A5 (ZIP5) IN THE ADAPTIVE RESPONSE TO ZINC AVAILABILITY  

E-Print Network (OSTI)

The aims of this research were to determine how Zip4 and Zip5 are regulated in response to zinc availability and how Zip4 impacts development. Loss of Zip4 resulted in embryonic lethality. Heterozygosity negatively affected eye, heart, and brain...

Weaver, Benjamin Patrick

2009-04-06T23:59:59.000Z

156

Self-Adaptive Management of The Sleep Depths of Idle Nodes in Large Scale Systems to Balance Between Energy Consumption and Response Times  

E-Print Network (OSTI)

Between Energy Consumption and Response Times Yongpeng Liu(1) , Hong Zhu(2) , Kai Lu(1) , Xiaoping Wang(1.659 MW, which equals the power usage of a middle scale city. In 2006, US servers and data centers U.S. electricity consumption or the output of about 15 typical power plants [2]. In 2007

Zhu, Hong

157

Establishing cytogenetic biodosimetry laboratory in Saudi Arabia and producing preliminary calibration curve of dicentric chromosomes as biomarker for medical dose estimation in response to radiation emergencies  

Science Journals Connector (OSTI)

In cases of individual radiation overexposure, it is important to provide suitable dose assessment, medical triage, diagnoses and treatment ... for effective medical management of a suspected acute radiation over...

Khaled Al-Hadyan; Sara Elewisy; Belal Moftah; Mohamed Shoukri; Awad Alzahrany

2014-04-01T23:59:59.000Z

158

Inference of Causal Networks from Time-course Transcription Data in Response to a2 Gy Challenge Dose of Ionizing Radiation with or without a 10 cGy Priming Dose  

NLE Websites -- All DOE Office Websites (Extended Search)

Causal Networks from Time-course Transcription Data in Response to a Causal Networks from Time-course Transcription Data in Response to a 2 Gy Challenge Dose of Ionizing Radiation with or without a 10 cGy Priming Dose Kai Zhang, Ju Han, Torsten Groesser, Priscilla Cooper, and Bahram Parvin Lawrence Berkeley National Laboratory Goal: To elucidate temporal-dependent gene templates, causal networks, and underlying biological processes that can be inferred in response to a 10 cGy priming dose with or without a later higher challenged dose. Background and significance: Mechanistic inference of regulatory network can provide new insights into radiation systems biology. The main challenge continues to be high dimensionality of data, complex network architecture and limited knowledge of biological processes.

159

Adaptive Sampling in Hierarchical Simulation  

SciTech Connect

We propose an adaptive sampling methodology for hierarchical multi-scale simulation. The method utilizes a moving kriging interpolation to significantly reduce the number of evaluations of finer-scale response functions to provide essential constitutive information to a coarser-scale simulation model. The underlying interpolation scheme is unstructured and adaptive to handle the transient nature of a simulation. To handle the dynamic construction and searching of a potentially large set of finer-scale response data, we employ a dynamic metric tree database. We study the performance of our adaptive sampling methodology for a two-level multi-scale model involving a coarse-scale finite element simulation and a finer-scale crystal plasticity based constitutive law.

Knap, J; Barton, N R; Hornung, R D; Arsenlis, A; Becker, R; Jefferson, D R

2007-07-09T23:59:59.000Z

160

The Effects of Chronic Restraint Stress on Innate and Adaptive Immune Responses to Acute Theiler?s Murine Encephalomyelitis Virus Infection ? An Animal Model of Human Multiple Sclerosis  

E-Print Network (OSTI)

. (May 2008) Andrew Steelman, B.S., Gardner-Webb University; M.BIOT., Texas A&M University Chair of Advisory Committee: Dr. C. Jane R. Welsh Multiple sclerosis (MS) is an immune-mediated prevalent chronic demyelinating and neurodegenerative disease... the IL-2R? (p = 2.96 x 10 -8 ), IL- 7R?, (p = 2.94 x 10 -7 ) and HLA-DRA locus (p = 8.94 x 10 -81 ) (Hafler et al., 2007). As these genes are strongly associated with CD4 + T-cell responses, these findings provide circumstantial evidence...

Steelman, Andrew Jonathan

2009-05-15T23:59:59.000Z

Note: This page contains sample records for the topic "radiation adaptive responses" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


161

Low Dose Radiation Research Program: Computational Modeling of Biochemical  

NLE Websites -- All DOE Office Websites (Extended Search)

Computational Modeling of Biochemical Pathways Linking Ionizing Computational Modeling of Biochemical Pathways Linking Ionizing Radiation to Cell Cycle Arrest, Apoptosis, and Tumor Incidence Authors: Yuchao Maggie Zhao and Rory Conolly Institutions: Center for Computational Systems Biology CIIT Centers for Health Research Long-Range Goal: To develop an integrated, computational framework for the prediction of low-dose-response to ionizing radiation (IR) in people. Methodology: To provide a flexible framework to evaluate mechanisms of cellular adaptive responses after exposure to IR, three progressively more complicated descriptions of biochemical pathways linking DNA damage with cell-cycle checkpoint control and apoptosis were developed. These descriptions focus on p53-dependent checkpoint arrest and apoptosis, p73-dependent apoptosis, and Chk2-dependent checkpoint arrest,

162

Radiation Damage in Nanostructured Metallic Films  

E-Print Network (OSTI)

with favorable microstructures and to investigate their response to radiation. The goals of this thesis are to study the radiation responses of several nanostructured metallic thin film systems, including Ag/Ni multilayers, nanotwinned Ag and nanocrystalline Fe...

Yu, Kaiyuan

2013-04-15T23:59:59.000Z

163

IONIZING RADIATION RISKS TO SATELLITE POWER SYSTEMS (SPS) WORKERS  

E-Print Network (OSTI)

Dose-Response Relationships for Radiation-Induced Cancer EstimationDose-Response Relationships for Radiation-Induced Cancer A general hypothesis for estimationof the total dose. Estimation of Space Radiation Induced

Lyman, J.T.

2010-01-01T23:59:59.000Z

164

Low Dose Radiation Research Program: A Paracrine Signal Mediates The Cell  

NLE Websites -- All DOE Office Websites (Extended Search)

A Paracrine Signal Mediates The Cell Transformation Response To Low A Paracrine Signal Mediates The Cell Transformation Response To Low Dose Gamma Radiation in JB6 Cells. Authors: Thomas J. Weber,1 Robert W. Siegel,2 Lye M. Markillie,1 William B. Chrisler,1 Xingye C. Lei,3 and Nancy H. Colburn4 Institutions: 1Cell Biology and Biochemistry, Pacific Northwest National Laboratory, Richland, Washington. 2Protein Function, Pacific Northwest National Laboratory, Richland, Washington. 3Statistical and Mathematical Sciences, Pacific Northwest National Laboratory, Richland, Washington. 4Gene Regulation Section, Laboratory of Cancer Prevention, National Cancer Institute at Frederick, Frederick, Maryland. The carcinogenic response to radiation is complex and may involve adaptive cellular responses as well as a bystander effect mediated by paracrine or

165

Radiation Sterilization of Prototype Military Foods. III. Pork Loin  

Science Journals Connector (OSTI)

...Spearman-KMirber estimation of an LD5o...independent of the dose-response...with- 610 RADIATION STERILIZATION...values with radiation dose, and the fluctuating...commercial radiation process for...Werkowski. 1968. Estimation of radiation...

Abe Anellis; D. Berkowitz; C. Jarboe; H. M. El-Bisi

1969-10-01T23:59:59.000Z

166

Radiation Emergency Medicine Fact Sheet  

NLE Websites -- All DOE Office Websites (Extended Search)

Improving Global Response Improving Global Response to Radiation Emergencies Improving Radiation Emergency Response Through Education and Specialized Expertise In the event of a radiological or nuclear incident, first responders as well as hospital and emergency management personnel must call on their knowledge and training to provide immediate and effective care for victims. Through practical, hands-on education programs, Oak Ridge Associated Universities (ORAU) is improving global response to radiation emergencies. In addition, dedicated 24/7 deployable teams of physicians, nurses, and health physicists from the Radiation Emergency Assistance Center/Training Site (REAC/TS), which is managed by ORAU for DOE/NNSA, provide expert medical management of radiological incidents

167

Nanofoams Response to Radiation Damage  

SciTech Connect

Conclusions of this presentation are: (1) np-Au foams were successfully synthesized by de-alloying process; (2) np-Au foams remain porous structure after Ne ion irradiation to 1 dpa; (3) SFTs were observed in irradiated np-Au foams with highest and intermediate flux, while no SFTs were observed with lowest flux; (4) SFTs were observed in irradiated np-Au foams at RT, whereas no SFTs were observed at LNT irradiation; (5) The diffusivity of vacancies in Au at RT is high enough so that the vacancies have enough time to agglomerate and thus collapse. As a result, SFTs were formed; (6) The high flux created much more damage/time, vacancies don't have enough time to diffuse or recombine. As a result, SFTs were formed.

Fu, Engang [Los Alamos National Laboratory; Serrano De Caro, Magdalena [Los Alamos National Laboratory; Wang, Yongqiang [Los Alamos National Laboratory; Nastasi, Michael [Nebraska Center for Energy Sciences Research, University of Nebraska-Lincoln, NE 68508; Zepeda-Ruiz, Luis [PLS, Lawrence Livermore National Laboratory, Livermore, CA 94551; Bringa, Eduardo M. [CONICET and Inst. Ciencias Basicas, Universidad Nacional de Cuyo, Mendoza, 5500 Argentina; Baldwin, Jon K. [Los Alamos National Laboratory; Caro, Jose A. [Los Alamos National Laboratory

2012-07-30T23:59:59.000Z

168

Effect of low-dose, low-LET γ-radiation and BaP injection on pulmonary  

NLE Websites -- All DOE Office Websites (Extended Search)

low-dose, low-LET γ-radiation and BaP injection on pulmonary low-dose, low-LET γ-radiation and BaP injection on pulmonary immunity in A/J mice K. Gott Lovelace Respiratory Research Institute Abstract Introduction: Low-dose, low-linear-energy-transfer (LET) radiation (LDR; < 100 mGy) activates the immune response (Nowosielska et al., 2006), presumably via epigenetic pathways (Scott et al., 2009) and has been implicated as suppressing both alpha-radiation-induced and smoking-related lung cancer (Scott et al. 2009). One of the hypothesized adaptive-response mechanisms by which LDR does so is by activating immune cell function in the lung, which would then increase their anti-cancer surveillance function (Liu, 2007; Bogdandi et al., 2010). One measure of activated immune cell function is their expression of markers on their cell surface that are

169

Climate adaptation planning in practice: an evaluation of adaptation plans from three developed nations  

SciTech Connect

Formal planning for climate change adaptation is emerging rapidly at a range of geo-political scales. This first generation of adaptation plans provides useful information regarding how institutions are framing the issue of adaptation and the range of processes that are recognized as being part of an adaptation response. To better understand adaptation planning among developed nations, a set of 57 adaptation plans from Australia, the United Kingdom and the United States was evaluated against a suite of 19 planning processes identified from existing guidance instruments for adaptation planning. Total scores among evaluated plans ranged from 16% of the maximum possible score to 61%, with an average of 37%. These results suggest adaptation plans are largely under-developed. Critical weaknesses in adaptation planning are related to limited consideration for non-climatic factors as well as neglect for issues of adaptive capacity including entitlements to various forms of capital needed for effective adaptation. Such gaps in planning suggest there are opportunities for institutions to make better use of existing guidance for adaptation planning and the need to consider the broader governance context in which adaptation will occur. In addition, the adaptation options prescribed by adaptation plans reflect a preferential bias toward low-risk capacity-building (72% of identified options) over the delivery of specific actions to reduce vulnerability. To the extent these findings are representative of the state of developed nation adaptation planning, there appear to be significant deficiencies in climate change preparedness, even among those nations often assumed to have the greatest adaptive capacity.

Preston, Benjamin L [ORNL; Westaway, Richard M. [IMS Consulting, Bristol, Avon, England; Yuen, Emma J. [CSIRO Climate Adaptation Flagship, Aspendale, Vic, Australia

2011-04-01T23:59:59.000Z

170

Radiation-Induced Bystander Effects and Relevance to Human Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation-Induced Bystander Effects and Relevance to Human Radiation Radiation-Induced Bystander Effects and Relevance to Human Radiation Exposures Review of phenomenon appears in Radiation Research Pamela Sykes and Benjamin Blyth One concern of radiobiologists is the effect radiation exposure might have on nearby unirradiated cells. For example, when only a small fraction of cells are directly hit by radiation energy, are the surrounding unirradiated cells also at an increased risk of cancer? The term "radiation-induced bystander effect" is used to describe radiation-induced biological changes that occur in unirradiated cells within an irradiated cell population. Radiation-induced bystander effects have become established in the vernacular and are considered as an authentic radiation response. However, there is still no consensus on a precise definition of the term, which

171

RHOBOT: Radiation hardened robotics  

SciTech Connect

A survey of robotic applications in radioactive environments has been conducted, and analysis of robotic system components and their response to the varying types and strengths of radiation has been completed. Two specific robotic systems for accident recovery and nuclear fuel movement have been analyzed in detail for radiation hardness. Finally, a general design approach for radiation-hardened robotics systems has been developed and is presented. This report completes this project which was funded under the Laboratory Directed Research and Development program.

Bennett, P.C.; Posey, L.D. [Sandia National Labs., Albuquerque, NM (United States)

1997-10-01T23:59:59.000Z

172

GRACE-2: integrating fine-grained application adaptation with global adaptation for saving energy  

Science Journals Connector (OSTI)

Energy efficiency has become a primary design criterion for mobile multimedia devices. Prior work has proposed saving energy through coordinated adaptation in multiple system layers, in response to changing application demands and system resources. The scope and frequency of adaptation pose a fundamental conflict in such systems. The Illinois GRACE project addresses this conflict through a hierarchical solution which combines: 1) infrequent (expensive) global adaptation that optimises energy for all applications in the system, 2) frequent (cheap) per-application (or per-app) adaptation that optimises for a single application at a time. This paper demonstrates the benefits of the hierarchical adaptation through a second-generation prototype, GRACE-2. Specifically, it shows that in a network bandwidth constrained environment, per-app application adaptation yields significant energy benefits over and above global adaptation.

Vibhore Vardhan; Wanghong Yuan; Albert F. Harris; Sarita V. Adve; Robin H. Kravets; Klara Nahrstedt; Daniel G. Sachs; Douglas L. Jones

2009-01-01T23:59:59.000Z

173

Alpha Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Basics of Radiation Basics of Radiation Gamma Radiation and X-Rays Beta Radiation Alpha Radiation Irradiation Radioactive Contamination Definitions Detection Measurement Safety Around Radiation Sources Types of Radiation Exposure Managing Radiation Emergencies Basics of Radiation Characteristics of Alpha Radiation 1. Alpha radiation is not able to penetrate skin. 2. Alpha-emitting materials can be harmful to humans if the materials are inhaled, swallowed, or absorbed through open wounds. 3. A variety of instruments have been designed to measure alpha radiation. Special training in use of these instruments is essential for making accurate measurements. 4. A civil defense instrument (CD V-700) cannot detect the presence of radioactive materials that produce alpha radiation unless the radioactive materials also produce beta and/or gamma radiation.

174

Radiation: Radiation Control (Indiana)  

Energy.gov (U.S. Department of Energy (DOE))

It is the policy of the state to encourage the constructive uses of radiation and to control its harmful effects. This section contains regulations pertaining to the manufacture, use,...

175

Effect of low-dose, low-LET γ-radiation and BaP injection on pulmonary immunity in A/J mice  

NLE Websites -- All DOE Office Websites (Extended Search)

low-dose, low-LET γ-radiation and BaP injection on pulmonary immunity in A/J mice low-dose, low-LET γ-radiation and BaP injection on pulmonary immunity in A/J mice K. Gott, V. Gonzales, M. Makvandi, N. Kikendall, A. Monier, E. Maloy, C. Rietz, B. Scott and J. Wilder. Lovelace Respiratory Research Institute, Albuquerque, NM Introduction: Low-dose, low-linear-energy-transfer (LET) radiation (LDR; < 100 mGy) activates the immune response (Nowosielska et al., 2006), presumably via epigenetic pathways (Scott et al., 2009) and has been implicated as suppressing both alpha-radiation-induced and smoking-related lung cancer (Scott et al. 2009). One of the hypothesized adaptive-response mechanisms by which LDR does so is by activating immune cell function in the lung, which would then increase their anti-cancer surveillance

176

Low Dose Ionizing Radiation Modulates Immune Function New Project Overview  

NLE Websites -- All DOE Office Websites (Extended Search)

Modulates Immune Function New Project Overview Modulates Immune Function New Project Overview Gregory Nelson Loma Linda University Abstract The immune system provides the first line of defense for exposures to environmental hazards. Protective immunity mechanisms using innate or adaptive responses are employed to mitigate acute challenges or amplify the readiness of the system to respond to future challenges. Some stimuli lead to amplified inflammatory reactions such as delayed hypersensitivity which is required for immunity to parasites and can also lead to adverse consequences such as contact dermatitis. Radiation exposure has the potential to aggravate hypersensitivity reactions as well as to suppress protective immunity. Ionizing radiation at high doses has long been recognized as highly effective in destroying cells of the immune system,

177

Sensor response rate accelerator  

SciTech Connect

An apparatus and method for sensor signal prediction and for improving sensor signal response time, is disclosed. An adaptive filter or an artificial neural network is utilized to provide predictive sensor signal output and is further used to reduce sensor response time delay.

Vogt, Michael C. (Westmont, IL)

2002-01-01T23:59:59.000Z

178

Adaptive mean filtering for noise reduction in CT polymer gel dosimetry  

SciTech Connect

X-ray computed tomography (CT) as a method of extracting 3D dose information from irradiated polymer gel dosimeters is showing potential as a practical means to implement gel dosimetry in a radiation therapy clinic. However, the response of CT contrast to dose is weak and noise reduction is critical in order to achieve adequate dose resolutions with this method. Phantom design and CT imaging technique have both been shown to decrease image noise. In addition, image postprocessing using noise reduction filtering techniques have been proposed. This work evaluates in detail the use of the adaptive mean filter for reducing noise in CT gel dosimetry. Filter performance is systematically tested using both synthetic patterns mimicking a range of clinical dose distribution features as well as actual clinical dose distributions. Both low and high signal-to-noise ratio (SNR) situations are examined. For all cases, the effects of filter kernel size and the number of iterations are investigated. Results indicate that adaptive mean filtering is a highly effective tool for noise reduction CT gel dosimetry. The optimum filtering strategy depends on characteristics of the dose distributions and image noise level. For low noise images (SNR {approx}20), the filtered results are excellent and use of adaptive mean filtering is recommended as a standard processing tool. For high noise images (SNR {approx}5) adaptive mean filtering can also produce excellent results, but filtering must be approached with more caution as spatial and dose distortions of the original dose distribution can occur.

Hilts, Michelle; Jirasek, Andrew [Medical Physics, BC Cancer Agency-Vancouver Island Centre, Victoria, British Columbia, V8R6V5 (Canada); Department of Physics and Astronomy, University of Victoria, Victoria, British Columbia, V8W2Y2 (Canada)

2008-01-15T23:59:59.000Z

179

Quantitative estimation of UV light dose concomitant to irradiation with ionizing radiation  

Science Journals Connector (OSTI)

A simple mathematical model for biological estimation of UV light dose concomitant to ionizing radiation was suggested. This approach was applied to determine the dependency of equivalent UV light dose accompanied by 100Gy of ionizing radiation on energy of sparsely ionizing radiation and on volume of the exposed cell suspension. It was revealed that the relative excitation contribution to the total lethal effect and the value of UV dose was greatly increased with an increase in energy of ionizing radiation and volume of irradiated suspensions. It is concluded that these observations are in agreement with the supposition that ?erenkov emission is responsible for the production of UV light damage and the phenomenon of photoreactivation observed after ionizing exposure of bacterial and yeast cells hypersensitive to UV light. A possible synergistic interaction of the damages produced by ionizations and excitations as well as a probable participation of UV component of ionizing radiation in the mechanism of hormesis and adaptive response observed after ionizing radiation exposure is discussed.

Vladislav G. Petin; Ivan I. Morozov; Jin Kyu Kim; Maria A. Semkina

2011-01-01T23:59:59.000Z

180

Risk Estimation; Background Radiation (Natural and Artificial )  

E-Print Network (OSTI)

-threshold mode estimate the response at lower doses. · The Committee on Biological Effects of Ionizing RadiationModule 9 Risk Estimation; Background Radiation (Natural and Artificial ) · sources of background radiation · various risk models. · estimating risk and on the sources of background radiation, both

Massey, Thomas N.

Note: This page contains sample records for the topic "radiation adaptive responses" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


181

Generalized Adaptive A* Xiaoxun Sun  

E-Print Network (OSTI)

Generalized Adaptive A* Xiaoxun Sun USC Computer Science Los Angeles, California xiaoxuns spaces changes. Adaptive A* [7] is a Cite as: Generalized Adaptive A*, Xiaoxun Sun, Sven Koenig

Yeoh, William

182

Prevention of Low Dose Radiation-Induced Genomic Instability with Clinically Relevant Non-Protein Thiols and Vitamin E.  

NLE Websites -- All DOE Office Websites (Extended Search)

Prevention of Low Dose Radiation-Induced Genomic Instability with Clinically Relevant Prevention of Low Dose Radiation-Induced Genomic Instability with Clinically Relevant Non-Protein Thiols and Vitamin E. J.S. Murley 1 , Y. Kataoka 1 , W.F. Morgan 2 , and D.J. Grdina 1 . The University of Chicago, Chicago, IL 1 , The University of Maryland Medical School, Baltimore, MD 2 Induced or delayed radioprotection is a novel phenomenon that shares many similarities with the low dose radiation-induced radiobiological phenomenon referred to as the adaptive response. Induced or delayed radioprotection is defined as an enhancement in the radiation resistance of cells at long times following their exposure to non-protein thiols (NPT) such as WR1065, the free thiol form of amifostine. This effect is the result of the induction of a cascade of intracellular

183

Ionizing radiation detector  

DOE Patents (OSTI)

An ionizing radiation detector is provided which is based on the principle of analog electronic integration of radiation sensor currents in the sub-pico to nano ampere range between fixed voltage switching thresholds with automatic voltage reversal each time the appropriate threshold is reached. The thresholds are provided by a first NAND gate Schmitt trigger which is coupled with a second NAND gate Schmitt trigger operating in an alternate switching state from the first gate to turn either a visible or audible indicating device on and off in response to the gate switching rate which is indicative of the level of radiation being sensed. The detector can be configured as a small, personal radiation dosimeter which is simple to operate and responsive over a dynamic range of at least 0.01 to 1000 R/hr.

Thacker, Louis H. (Knoxville, TN)

1990-01-01T23:59:59.000Z

184

Pantex Plant Emergency Response Exercise  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Joint Information Center Emergency Manager Offsite Interface Coordinator DOE Technical Advisor Emergency Press Center Radiation Safety Figure 1. Pantex Plant Emergency Response...

185

The genomics of adaptation  

Science Journals Connector (OSTI)

...introduction Special feature 1001 70 197 198 The genomics of adaptation Jacek Radwan 1 * Wieslaw...One contribution to a Special Feature Genomics of adaptation. The amount and nature...aspects of the broad field of adaptation genomics. This introductory article sets up a...

2012-01-01T23:59:59.000Z

186

Investigation of non-targeted effects of low dose ionizing radiation on the mammary gland  

NLE Websites -- All DOE Office Websites (Extended Search)

non-targeted effects of low dose ionizing radiation on the mammary gland non-targeted effects of low dose ionizing radiation on the mammary gland utilizing three-dimensional culture models of mammary cells derived from mouse strains that differ in susceptibility to tumorigenesis Joni D. Mott, Antoine M. Snijders, Alvin Lo, Dinah Levy-Groesser, Bahram Parvin, Andrew J. Wyrobek, Jian-Hua Mao, and Mina J. Bissell Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley CA 94720 Goal: Within the Lawrence Berkeley National Laboratory's SFA, Project 2, our studies focus on utilizing three dimensional (3D) cell culture models as surrogates for in vivo studies to determine how low doses of ionizing radiation influence mammary gland tissue architecture and how this may relate both to tumor progression and/or adaptive response.

187

On adaptive grid computations of variable stars  

SciTech Connect

We show that the use of an implicit adaptive-grid technique is an efficient and up-to-date approach for the calculations of radial oscillations in variable stars. We chose as an illustrative example the radiative envelope of an RR Lyrae variable. For the hydrostatic initial model we compare the Lagrangean ratioed zoning with an adaptive-grid rezoning. We show that the adaptive-grid yields an optimal distribution of the mesh points in the sense that the relevant physical features, the H{minus} and He 1{minus}, He 2{minus} ionization zones, are well resolved. For the hydrodynamical evolution we present the full-amplitude model for both the Lagrangean and adaptive-grid computations. We perform a detailed comparison and show that the adaptive-grid method yields limit cycle solutions that are substantially improved over the Lagrangean grid model. This is due to the fact that the Lagrangean mesh sweeps through the ionization zones twice during one oscillation period, whereas the adaptive-mesh resolves them and tracks them continuously. The results are, in particular, smooth radial velocity and light curves. Beyond a physically better defined solution we also observe larger time steps for the convergence towards the limit cycle and for the evolution during one period. 12 refs., 13 figs., 5 tabs.

Cox, A.N.; Deupree, R.G.; Gehmeyr, M.

1991-01-01T23:59:59.000Z

188

Effects of Solar UV Radiation on Morphology and Photosynthesis of Filamentous Cyanobacterium Arthrospira platensis  

Science Journals Connector (OSTI)

...time of exposure to solar radiation (E and F). (A and...E and F) daily solar doses during the exposure period...Cyanobacteria growth & development radiation effects ultrastructure Dose-Response Relationship, Radiation Photosynthesis radiation...

Hongyan Wu; Kunshan Gao; Virginia E. Villafae; Teruo Watanabe; E. Walter Helbling

2005-09-01T23:59:59.000Z

189

About Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation Radiation What is radiation? Radiation is a form of energy that is a part of our everyday lives. All of us receive a "dose" of radiation each day. Most of the dose comes from naturally occurring radioactive materials such as uranium, thorium, radon, and certain forms of potassium and carbon. The air we breathe contains radon, the food we eat contains uranium and thorium from the soil, and our bodies contain radioactive forms of potassium and carbon. Cosmic radiation from the sun also contributes to our natural radiation dose. We also receive radiation doses from man-made sources such as X-rays, nuclear medical procedures, power plants, smoke detectors and older television sets. Some people, such as nuclear plant operators, flight crews, and nuclear medicine staff may also receive an occupational radiation dose.

190

Radiation hormesis research findings and therapeutic applications  

Science Journals Connector (OSTI)

In 1982, Professor Thomas Don Luckey of Missouri University asserted 'radiation hormesis' in the journal Health Physics. Following his assertion, the CRIEPI initiated a research programme on radiation hormesis to confirm 'is it true or not'. Twelve years of research with 8??14 universities in Japan produced fruitful results on radiation hormesis. Hormone response tests on rabbits, enzyme response tests on rats and mice, p53 gene responses from mice and rats and helper-T responses from human patients gave us impressive information to consider the therapeutic application of radiation hormesis.

Sadao Hattori

2005-01-01T23:59:59.000Z

191

Modelling of Radiative Transfer in Light Sources  

E-Print Network (OSTI)

. . . . . . . . . . . . . . . 30 2.5.3 Temperature distribution . . . . . . . . . . . . . . . . . . . . . . . . . 32 2-X radiative transition that is responsible for the sulfur lamp's bright sun-like spectrum #12;Contents 1

Eindhoven, Technische Universiteit

192

Environment/Health/Safety (EHS): Radiation Protection Group: Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Who To Call Who To Call Rad Training Dosimetry Telemetry Laser Safety Radiation Safety Committee Pub-3000 Ch. 21 Forms RPG Procedures RPG Internal Radiation Safety Committee Charter Purpose The Berkeley Lab Radiation Safety Committee (RSC) is appointed by, and reports to, the Laboratory Director and is responsible for advising LBNL Management on all matters related to occupational and environmental radiation safety. The Radiation Safety Committee reviews and recommends approval of radiation safety policies and guides the Environment, Health and Safety Division and radiation user divisions in carrying out these programs. The scope of its actions will generally be in issues of broad institutional concern and impact, or areas of potential high consequence either in terms of safety or institutional needs.

193

Adaptive Video Retrieval  

E-Print Network (OSTI)

Hopfgartner,F. Villa,R. Urban,J. Jose,J.M. Proceedings of the First International Workshop on Adaptive Information Retrieval pp 28-29

Hopfgartner, F.

194

Danger radiations  

ScienceCinema (OSTI)

Le confrencier Mons.Hofert parle des dangers et risques des radiations, le contrle des zones et les prcautions prendre ( p.ex. film badge), comment mesurer les radiations etc.

None

2011-04-25T23:59:59.000Z

195

E-Print Network 3.0 - activity trial adapt Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

Biology and Medicine 6 Running Head: CONFLICT ADAPTATION FOLLOWING ERRONEOUS RESPONSE PREPARATION Summary: (Botvinick et al., 2001). Reduced ACC activation (sometimes...

196

E-Print Network 3.0 - adaptive supply survival Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

Sciences and Ecology 6 RICKARD, I.J. & LUMMAA V. 2007: The Predictive Adaptive Response and metabolic syndrome: Challenges for the hypothesis. Summary: 1: survival...

197

E-Print Network 3.0 - adaptive phased array Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

the desired array response; in this case... of adaptive beamformers on seismic data ... Source: van der Veen, Alle-Jan - Department of Electrical Engineering, Technische...

198

High-let radiation carcinogenesis  

SciTech Connect

Recent results for neutron radiation-induced tumors are presented to illustrate the complexities of the dose-response curves for high-LET radiation. It is suggested that in order to derive an appropriate model for dose-response curves for the induction of tumors by high-LET radiation it is necessary to take into account dose distribution, cell killing and the susceptibility of the tissue under study. Preliminary results for the induction of Harderian gland tumors in mice exposed to various heavy ion beams are presented. The results suggest that the effectiveness of the heavy ion beams increases with increasing LET. The slopes of the dose-response curves for the different high-LET radiations decrease between 20 and 40 rads and therefore comparisons of the relative effectiveness should be made from data obtained at doses below about 20 to 30 rads.

Fry, R.J.M.; Powers-Risius, P.; Alpen, E.L.; Ainsworth, E.J.; Ullrich, R.L.

1982-01-01T23:59:59.000Z

199

Leak test adapter for containers  

DOE Patents (OSTI)

An adapter is provided for facilitating the charging of containers and leak testing penetration areas. The adapter comprises an adapter body and stem which are secured to the container's penetration areas. The container is then pressurized with a tracer gas. Manipulating the adapter stem installs a penetration plug allowing the adapter to be removed and the penetration to be leak tested with a mass spectrometer. Additionally, a method is provided for using the adapter.

Hallett, Brian H. (Elizabeth, PA); Hartley, Michael S. (Canonsburg, PA)

1996-01-01T23:59:59.000Z

200

Exploring early public responses to geoengineering  

Science Journals Connector (OSTI)

...January and 26 March 2010. Computer-assisted personal interviews were conducted by...know) (iii) Question C. Support for solar radiation management and carbon dioxide...Interviewee responses to examples of solar radiation management The interview study...

2012-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "radiation adaptive responses" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


201

Radiation and viral DNA  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation and viral DNA Radiation and viral DNA Name: Loretta L Lamb Age: N/A Location: N/A Country: N/A Date: N/A Question: Can viral DNA be changed through exposure to radiation? If so, what type of radiation will do this? Can these irradiated viruses cause changes in the genome of any human cells they may infect? Can these (or any) viruses actually cause cancer, or do they merely act as triggering devices for cancer? Replies: In theory, any nucleic acid (viral or otherwise) can be changed by exposure to many kinds of radiation. Depending on the type of virus, these may then change the human cells that they infect. Although there are many different things that are being implicated in causing cancers, it looks like a fairly common model involves the sequential "knockout" of several human genes. Viruses may be one cause of such gene changes, radiation and other environmental causes may also contribute. Some of these changes may be inherited through families, so it becomes more likely that the environmental factors may happen to "hit" the right places in cells to cause cancers in these families. If you ask something more specific, perhaps I can focus my response a bit more

202

Induction by ionizing radiation of the gadd45 gene in cultured human cells: lack of mediation by protein kinase C.  

Science Journals Connector (OSTI)

...coordinately induced by UV radiation and alkylating agents...rapidly after X rays at doses as low as 2 Gy. After...isolation & purification radiation effects DNA Damage Dose-Response Relationship, Radiation Genes radiation effects...

M A Papathanasiou; N C Kerr; J H Robbins; O W McBride; I Alamo Jr; S F Barrett; I D Hickson; A J Fornace Jr

1991-02-01T23:59:59.000Z

203

BIODIVERSITY Incorporating sociocultural adaptive  

E-Print Network (OSTI)

BIODIVERSITY VIEWPOINT Incorporating sociocultural adaptive capacity in conservation hotspot of biodiversity threats. Conservation biogeography (Whittaker et al., 2005) has emerged as a critical area biodiversity (Mawdsley et al., 2009). Adjusting conservation strategies to maintain diversity in recognition

204

Adaptive Street Lighting Controls  

Energy.gov (U.S. Department of Energy (DOE))

This two-partDOE Municipal Solid-State Street Lighting Consortium webinar focused on LED street lighting equipped with adaptive control components. In Part I, presenters Amy Olay of the City of...

205

Dynamic Adaptation using Xen  

SciTech Connect

The topic of virtualization has received renewed attention. Xen is a popular open source type-I hypervisor. The Xen hypervisor currently has limited capabilities for runtime modification to the core hypervisor, which impairs research into dynamic adaptation for system-level virtualization. This paper discusses recent investigations into the feasibility of extending Xen to support runtime adaptation for core hypervisor service, e.g., scheduler.

Naughton, III, Thomas J [ORNL; Vallee, Geoffroy R [ORNL; Scott, Stephen L [ORNL

2007-01-01T23:59:59.000Z

206

Plasma Radiation  

Science Journals Connector (OSTI)

... JUST over ten years ago the first book on plasma physics as a subject in its own right appeared; in a gradually swelling stream ... been surprisingly few monographs. One topic which has had scant coverage in any form is plasma radiation (except for spectral-line radiation which has been dealt with very fully in ...

T. J. M. BOYD

1967-07-01T23:59:59.000Z

207

Low Dose Radiation Research Program: Low Dose Radiation Effects in  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation Effects in Differentiating Human Lens Cells Radiation Effects in Differentiating Human Lens Cells E.A. Blakely1, M.P. McNamara1, P.Y. Chang1, K.A. Bjornstad1, D. Sudar1, and A.C. Thompson2 1Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California; 2Advanced Light Source Division, Lawrence Berkeley National Laboratory, Berkeley, California. Introduction The human lens is one of the most radiosensitive organs of the body. Cataract, the opacification of the lens, is a late-appearing response to radiation damage. There are few data available on the late radiation effects of exposure in space flight to charged particle beams, the most prevalent of which are protons. Basic research in this area is needed to integrate the responses of both critical and other representative tissues

208

GADRAS Detector Response Function.  

SciTech Connect

The Gamma Detector Response and Analysis Software (GADRAS) applies a Detector Response Function (DRF) to compute the output of gamma-ray and neutron detectors when they are exposed to radiation sources. The DRF is fundamental to the ability to perform forward calculations (i.e., computation of the response of a detector to a known source), as well as the ability to analyze spectra to deduce the types and quantities of radioactive material to which the detectors are exposed. This document describes how gamma-ray spectra are computed and the significance of response function parameters that define characteristics of particular detectors.

Mitchell, Dean J.; Harding, Lee; Thoreson, Gregory G; Horne, Steven M.

2014-11-01T23:59:59.000Z

209

Safety and Immunologic Response of a Viral Vaccine to Prostate-Specific Antigen in Combination with Radiation Therapy when Metronomic-Dose Interleukin 2 Is Used as an Adjuvant  

Science Journals Connector (OSTI)

...trial showed the safety and feasibility...vaccine with radiation therapy, but...using FlowJo software (BD Biosciences...926-31. Safety and immunologic...combination with radiation therapy when...external beam radiation therapy was initiated...evaluated for safety and immunologic...

Robert J. Lechleider; Philip M. Arlen; Kwong-Yok Tsang; Seth M. Steinberg; Junko Yokokawa; Vittore Cereda; Kevin Camphausen; Jeffrey Schlom; William L. Dahut; and James L. Gulley

2008-08-15T23:59:59.000Z

210

Adaptation and risk management  

SciTech Connect

Adaptation assessment methods are compatible with the international risk management standard ISO:31000. Risk management approaches are increasingly being recommended for adaptation assessments at both national and local levels. Two orientations to assessments can commonly be identified: top-down and bottom-up, and prescriptive and diagnostic. Combinations of these orientations favor different types of assessments. The choice of orientation can be related to uncertainties in prediction and taking action, in the type of adaptation and in the degree of system stress. Adopting multiple viewpoints is to be encouraged, especially in complex situations. The bulk of current guidance material is consistent with top-down and predictive approaches, thus is most suitable for risk scoping and identification. Abroad range ofmaterial fromwithin and beyond the climate change literature can be used to select methods to be used in assessing and implementing adaptation. The framing of risk, correct formulation of the questions being investigated and assessment methodology are critical aspects of the scoping phase. Only when these issues have been addressed should be issue of specific methods and tools be addressed. The reorientation of adaptation from an assessment focused solely on anthropogenic climate change to broader issues of vulnerability/resilience, sustainable development and disaster risk, especially through a risk management framework, can draw from existing policy and management understanding in communities, professions and agencies, incorporating existing agendas, knowledge, risks, and issues they already face.

Preston, Benjamin L [ORNL

2011-01-01T23:59:59.000Z

211

Radiation dosimeter  

DOE Patents (OSTI)

A radiation detector readout circuit is provided which produces a radiation dose-rate readout from a detector even though the detector output may be highly energy dependent. A linear charge amplifier including an output charge pump circuit amplifies the charge signal pulses from the detector and pumps the charge into a charge storage capacitor. The discharge rate of the capacitor through a resistor is controlled to provide a time-dependent voltage which when integrated provides an output proportional to the dose-rate of radiation detected by the detector. This output may be converted to digital form for readout on a digital display.

Fox, Richard J. (Oak Ridge, TN)

1983-01-01T23:59:59.000Z

212

Radiation dosimeter  

DOE Patents (OSTI)

A radiation detector readout circuit is provided which produces a radiation dose-rate readout from a detector even through the detector output may be highly energy dependent. A linear charge amplifier including an output charge pump circuit amplifies the charge signal pulses from the detector and pumps the charge into a charge storage capacitor. The discharge rate of the capacitor through a resistor is controlled to provide a time-dependent voltage which when integrated provides an output proportional to the dose-rate of radiation detected by the detector. This output may be converted to digital form for readout on a digital display.

Fox, R.J.

1981-09-01T23:59:59.000Z

213

The low dose damage response pathways in the mouse mammary glands depends  

NLE Websites -- All DOE Office Websites (Extended Search)

low dose damage response pathways in the mouse mammary glands depends low dose damage response pathways in the mouse mammary glands depends on genotype, tissue compartment, exposure regimen, and sampling times Joe Gray & Andrew Wyrobek Lawrence Berkeley National Laboratory Abstract The objectives of this research are to characterize the early and persistent low-dose and adaptive response (AR) damage surveillance networks in mammary glands of radiation sensitive and resistant strains of mice to identify the molecular signatures/mechanisms associated with nonlinear modifications of risk for mammary gland cancer. Our approach uses low-dose exposure regimens that have been reported to induce mammary gland cancer in sensitive strains to determine whether low-dose induced pathways are differentially expressed in epithelial or stromal cells and to determine

214

Integration of video and radiation analysis data  

SciTech Connect

We have introduced a new method to integrate spatial (digital video) and time (radiation monitoring) information. This technology is based on pattern recognition by neural networks, provides significant capability to analyze complex data, and has the ability to learn and adapt to changing situations. This technique could significantly reduce the frequency of inspection visits to key facilities without a loss of safeguards effectiveness.

Menlove, H.O.; Howell, J.A.; Rodriguez, C.A.; Eccleston, G.W.; Beddingfield, D.; Smith, J.E. [Los Alamos National Lab., NM (United States); Baumgart, C.W. [EG and G Energy Measurements, Inc., Los Alamos, NM (United States)

1994-08-01T23:59:59.000Z

215

Atomistic simulations of radiation damage in amorphous metal alloys  

E-Print Network (OSTI)

While numerous fundamental studies have characterized the atomic-level radiation response mechanisms in irradiated crystalline alloys, comparatively little is known regarding the mechanisms of radiation damage in amorphous ...

Baumer, Richard E. (Richard Edward)

2013-01-01T23:59:59.000Z

216

Biological dosimetry assessments of a serious radiation accident in Bulgaria in 2011  

Science Journals Connector (OSTI)

......Protection and Nuclear Safety (IRSN). REFERENCES...and Response to Radiation Emergencies Emergency...Dose estimation software for radiation biodosimetry. Health...and Treatment of Radiation Injuries. (1998) Safety Reports Series No......

E. Grgoire; V. Hadjidekova; R. Hristova; G. Gruel; S. Roch-Lefevre; P. Voisin; A. Staynova; S. Deleva; E. A. Ainsbury; D. C. Lloyd; J. F. Barquinero

2013-08-01T23:59:59.000Z

217

Extremely Low Dose Ionizing Radiation Up-regulates CXC Chemokines in Normal Human Fibroblasts  

Science Journals Connector (OSTI)

...with radiation exposure (1). Ionizing radiation at moderate and higher doses (0.1-10 Gy) can produce DNA strand...death. Studies of mutants sensitive to ionizing radiation at this range of doses have revealed that the responsible genes...

Akira Fujimori; Ryuichi Okayasu; Hiroshi Ishihara; Satoshi Yoshida; Kiyomi Eguchi-Kasai; Kumie Nojima; Satoru Ebisawa; and Sentaro Takahashi

2005-11-15T23:59:59.000Z

218

Inactivation of aflatoxin B1 by using the synergistic effect of hydrogen peroxide and gamma radiation.  

Science Journals Connector (OSTI)

...peroxide. A 100-krad dose of gamma radiation was sufficient to inactivate...peroxide. A 100-krad dose of gamma radiation was sufficient to inactivate...inhibitors pharmacology radiation effects Animals Dose-Response Relationship...

U D Patel; P Govindarajan; P J Dave

1989-02-01T23:59:59.000Z

219

Appendix G. Radiation Appendix G. Radiation  

E-Print Network (OSTI)

-made sources. People are exposed to naturally occurring radiation constantly. For example, cosmic radiation of radiation and its effects on the environment and biological systems. Radiation comes from natural and humanAppendix G. Radiation #12;#12;Appendix G. Radiation This appendix presents basic facts about

Pennycook, Steve

220

Adaptive filters for detection of gravitational waves from coalescing binaries  

SciTech Connect

In this work we propose use of infinite impulse response adaptive line enhancer (IIR ALE) filters for detection of gravitational waves from coalescing binaries. We extend our previous work and define an adaptive matched filter structure. Filter performance is analyzed in terms of the tracking capability and determination of filter parameters. Furthermore, following the Neyman-Pearson strategy, receiver operating characteristics are derived, with closedform expressions for detection threshold, false alarm, and detection probability. Extensive tests demonstrate the effectiveness of adaptive filters both in terms of small computational cost and robustness.

Eleuteri, Antonio; Milano, Leopoldo; De Rosa, Rosario; Garufi, Fabio; Acernese, Fausto; Barone, Fabrizio; Giordano, Lara; Pardi, Silvio [Dip. di Scienze Fisiche, Universita di Napoli 'Federico II', via Cintia, I-80126 Naples (Italy) and INFN sez. Napoli, via Cintia, I-80126 Naples (Italy); Dip. di Scienze Farmaceutiche, Universita di Salerno, via Ponte Don Melillo, 84084 Fisciano (Saudi Arabia) (IT) and INFN sez. Napoli, via Cintia, I-80126 Naples (Italy); Dip. di Matematica ed Applicazioni, Universita di Napoli 'Federico II', via Cintia, I-80126 Naples (Italy) and INFN sez. Napoli, via Cintia, I-80126 Naples (Italy)

2006-06-15T23:59:59.000Z

Note: This page contains sample records for the topic "radiation adaptive responses" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


221

Climate Change Adaptation Planning  

E-Print Network (OSTI)

of Colorado Law School #12;What is Climate Change Adaptation? "Adjustment in natural or human systems: Vulnerability and Risk Assessments - Current Example - Golden Eagles on the Colorado Plateau Current impact: Golden eagle populations have been declining in portions of the western U.S. Source: BLM Colorado Plateau

Neff, Jason

222

Climate Change Adaptation | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Climate Change Adaptation Climate Change Adaptation Mission The Climate Change Adaptation (CCA) team affirms the overall DOE commitment to plan for and manage the short and...

223

ON AN ADAPTIVE CONTROL ALGORITHM FOR ADAPTIVE OPTICS APPLICATIONS  

E-Print Network (OSTI)

ON AN ADAPTIVE CONTROL ALGORITHM FOR ADAPTIVE OPTICS APPLICATIONS MOODY T. CHU \\Lambda Abstract. The wavefront aberrations induced by atmospheric turbulence can severely degrade the performance of an optical imaging system. Adaptive optics refers to the process of removing unwanted wave front distortions

224

ON AN ADAPTIVE CONTROL ALGORITHM FOR ADAPTIVE OPTICS APPLICATIONS  

E-Print Network (OSTI)

ON AN ADAPTIVE CONTROL ALGORITHM FOR ADAPTIVE OPTICS APPLICATIONS MOODY T. CHU Abstract. The wavefront aberrations induced by atmospheric turbulence can severely degrade the performance of an optical imaging system. Adaptive optics refers to the process of removing unwanted wave front distortions

225

Instrument response in complex radiation fields  

Science Journals Connector (OSTI)

......placed in front of an ISO water phantom (30 30 15 cm3...Project study of an advanced facility for exotic beams...PHITS: a particle and heavy ion transport code system...equation of state in heavy ion collisions. Phys...Reaction Data and Nuclear Reactors Physics, Design and......

Stefano Agosteo; Marco Silari; Luisa Ulrici

2009-11-01T23:59:59.000Z

226

Instrument response in complex radiation fields  

Science Journals Connector (OSTI)

......medicine and experimental plants for research in thermonuclear fusion, and discusses the main techniques adopted for...fields at European high-energy accelerators and thermonuclear fusion facilities. Geneva. CERN-2006-007 (July......

Stefano Agosteo; Marco Silari; Luisa Ulrici

2009-11-01T23:59:59.000Z

227

Instrument response in complex radiation fields  

Science Journals Connector (OSTI)

......are based on epidemiological studies of cancer induction as well as on experimental genetic...leads to charge collection outside the depleted region; (ii) the electric noise limits...an aluminium wafer containing enriched uranium). This package was placed inside two......

Stefano Agosteo; Marco Silari; Luisa Ulrici

2009-11-01T23:59:59.000Z

228

Adaptation of Microvasculature to Pulsatility  

E-Print Network (OSTI)

adaptation has not yet been fully characterized. In fact, standard mathematical models using the common assumption that vessels solely adapt to steady flow do not reproduce normal vascular structure. Therefore, we developed a simple, mathematical model of a...

Bimal, Tia

2013-09-24T23:59:59.000Z

229

Diversification in a fluctuating island setting: rapid radiation of Ohomopterus ground beetles in the Japanese Islands  

Science Journals Connector (OSTI)

...setting: rapid radiation of Ohomopterus ground...Kyoto 606-8502, Japan The Japanese Islands...isolation. This radiation was achieved without...morphology). beetles|Japan|divergence time...ecology of adaptive radiation. In Oxford University...District, western Japan. Kontyu Tokyo...

2008-01-01T23:59:59.000Z

230

Project: (version of January 28, 2009) Sparse tensor product methods for radiative transfer  

E-Print Network (OSTI)

simulating a dense gas at very high temperatures, energy transport by means of radiation has to be taken into account. However, as even the non-scattering stationary monochromatic radiative transfer equation s · x. Applying an adaptive sparse discretiza- tion to the radiative transfer equation [1] allows to significantly

Hiptmair, Ralf

231

Low-Dose/Dose-Rate Low-LET Radiation Protects Us from Cancer  

NLE Websites -- All DOE Office Websites (Extended Search)

Dose/Dose-Rate Low-LET Radiation Protects Us from Cancer Dose/Dose-Rate Low-LET Radiation Protects Us from Cancer Bobby R. Scott, Ph.D. and Jennifer D. Di Palma Lovelace Respiratory Research Institute, 2425 Ridgecrest Drive SE Albuquerque, NM 87108 USA Life on earth evolved in a low-level ionizing radiation environment comprised of terrestrial radiation and cosmic rays. Today we all reside in an ionizing radiation environment comprised of both natural background radiation and radiation from human activities (e.g., Chernobyl accident). An evolutionary benefit of the interaction of low-level, low linear-energy-transfer (LET) ionizing radiation with mammalian life forms on earth is adapted protection. Adapted protection involves low-dose/dose-rate, low-LET radiation induced high-fidelity DNA repair in cooperation with normal apoptosis (presumed p53

232

Radiation receiver  

DOE Patents (OSTI)

The apparatus for collecting radiant energy and converting same to alternate energy form includes a housing having an interior space and a radiation transparent window allowing, for example, solar radiation to be received in the interior space of the housing. Means are provided for passing a stream of fluid past said window and for injecting radiation absorbent particles in said fluid stream. The particles absorb the radiation and because of their very large surface area, quickly release the heat to the surrounding fluid stream. The fluid stream particle mixture is heated until the particles vaporize. The fluid stream is then allowed to expand in, for example, a gas turbine to produce mechanical energy. In an aspect of the present invention properly sized particles need not be vaporized prior to the entrance of the fluid stream into the turbine, as the particles will not damage the turbine blades. In yet another aspect of the invention, conventional fuel injectors are provided to inject fuel into the fluid stream to maintain the proper temperature and pressure of the fluid stream should the source of radiant energy be interrupted. In yet another aspect of the invention, an apparatus is provided which includes means for providing a hot fluid stream having hot particles disbursed therein which can radiate energy, means for providing a cooler fluid stream having cooler particles disbursed therein, which particles can absorb radiant energy and means for passing the hot fluid stream adjacent the cooler fluid stream to warm the cooler fluid and cooler particles by the radiation from the hot fluid and hot particles. 5 figs.

Hunt, A.J.

1983-09-13T23:59:59.000Z

233

NNSA to Conduct Aerial Radiation Assessment Survey over Joint...  

National Nuclear Security Administration (NNSA)

of naturally occurring radiation to establish baseline levels is a normal part of security and emergency preparedness. This assessment is not in response to an incident or...

234

Louisiana Nuclear Energy and Radiation Control Law (Louisiana)  

Energy.gov (U.S. Department of Energy (DOE))

The Louisiana Department of Environmental Quality is responsible for the regulation of nuclear energy safety, permitting and radiation safety and control in Louisiana. The Department operates...

235

Electrical Analogs of Atomic Radiative Decay Processes  

E-Print Network (OSTI)

Simple electrical circuits are analyzed, and the results show that for high frequencies they have frequency and time responses identical to the spontaneous radiative decays of atoms. As an illustration of the analogy a ...

Fontana, Peter R.; Srivastava, Rajendra P.

1977-03-01T23:59:59.000Z

236

Radiation Protection Act (Pennsylvania)  

Energy.gov (U.S. Department of Energy (DOE))

This Act combines the radiation safety provisions of The Atomic Energy Development and Radiation Control Act and the Environmental Radiation Protection Act, and empowers the Department of...

237

Diversification and the adaptive radiation of the vangas of Madagascar  

Science Journals Connector (OSTI)

...We also thank Associate Editor Trevor Price, Per Alstrom, and an anonymous reviewer...10.1098/rspb.1997.0094 ) 22 Wit, M. J. 2003 Madagascar: heads it's...54 Phillimore, A. B. , and T. D. Price 2008 Density-dependent cladogenesis...

2012-01-01T23:59:59.000Z

238

RADIATION LABORATO DISCLAIMER  

NLE Websites -- All DOE Office Websites (Extended Search)

R : R : . . . RADIATION LABORATO DISCLAIMER This report was prepared as an account of work sponsored by an agency of the United States Government. Neither the United States Government nor any agency Thereof, nor any of their employees, makes any warranty, express or implied, or assumes any legal liability or responsibility for the accuracy, completeness, or usefulness of any information, apparatus, product, or process disclosed, or represents that its use would not infringe privately owned rights. Reference herein to any specific commercial product, process, or service by trade name, trademark, manufacturer, or otherwise does not necessarily constitute or imply its endorsement, recommendation, or favoring by the United States Government or any

239

Radiation imaging apparatus  

DOE Patents (OSTI)

A radiation imaging system using a charge multiplier and a position sensitive anode in the form of periodically arranged sets of interconnected anode regions for detecting the position of the centroid of a charge cloud arriving thereat from the charge multiplier. Various forms of improved position sensitive anodes having single plane electrode connections are disclosed. Various analog and digital signal processing systems are disclosed, including systems which use the fast response of microchannel plates, anodes and preamps to perform scintillation pulse height analysis digitally. 15 figs.

Anger, H.O.; Martin, D.C.; Lampton, M.L.

1983-07-26T23:59:59.000Z

240

Radiation imaging apparatus  

DOE Patents (OSTI)

A radiation imaging system using a charge multiplier and a position sensitive anode in the form of periodically arranged sets of interconnected anode regions for detecting the position of the centroid of a charge cloud arriving thereat from the charge multiplier. Various forms of improved position sensitive anodes having single plane electrode connections are disclosed. Various analog and digital signal processing systems are disclosed, including systems which use the fast response of microchannel plates, anodes and preamps to perform scintillation pulse height analysis digitally.

Anger, Hal O. (Berkeley, CA); Martin, Donn C. (Berkeley, CA); Lampton, Michael L. (Berkeley, CA)

1983-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "radiation adaptive responses" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


241

Operational radiation protection in high-energy physics accelerators  

Science Journals Connector (OSTI)

......monitors with a good energy response have been built...to increase their response at high energies(6)). Prompt radiation...often pulsed, with a frequency that can range between millions of Hz in a storage ring and less than......

S. H. Rokni; A. Fass; J. C. Liu

2009-11-01T23:59:59.000Z

242

Radiation protection: Natural radiation risks  

Science Journals Connector (OSTI)

... radiation to which humans are exposed consists of four components - cosmic, gamma, internal, radon. The relative contribution that each makes to the sum is shown in the chart. ... but exposure of the whole body to terrestrial gamma rays and of the lungs to radon daughters are influenced by the nature and location of housing. Gamma rays are emitted ...

M. C. O'Riordan

1983-11-17T23:59:59.000Z

243

Responses of Synchronous L5178Y S/S Cells to Heavy Ions and Their Significance for Radiobiological Theory  

Science Journals Connector (OSTI)

...viruses by ionizing radiations, so far the response...attributed to secondary radiations ( rays) and smaller...beams were in the range of 460 +/- 95...as the baseline radiation. Generally, the...certain viruses by ionizing radiations, so...radiation effects Dose-Response Relationship...

1989-01-01T23:59:59.000Z

244

Inactivation of carotenoid-producing and albino strains of Neurospora crassa by visible light, blacklight, and ultraviolet radiation.  

Science Journals Connector (OSTI)

...DNA, Bacterial radiation effects Dose-Response Relationship, Radiation Haemophilus influenzae...involved in the estimation of average fluence...R. W. 1956. Dose-effect curves...of' ultraviolet radiation on carotenoid containing...

P L Blanc; R W Tuveson; M L Sargent

1976-02-01T23:59:59.000Z

245

Genomic and Expression Analyses of Cold-Adapted Microorganisms.  

SciTech Connect

Contents 7.1 Introduction 7.2 Ecological evidence of bacterial adaptation to cold 7.2.1 Characteristics of cold environments and implications for microbial ecology 7.2.2 Ecological adaptation in Exiguobacterium spp. and Psychrobacter spp. 7.3 Gene Expression Responses to the Cold 7.3.1 Fundamentals of Gene Expression Responses to Cold 7.3.2 Acclimation for Life in Cold Habitats 7.3.2.1 Translation and Chaperone Proteins: Safeguarding the functional units of cellular physiology 7.3.2.2 Carbon and Energy metabolism: resource efficiency over long generation times 7.3.2.3 Amino Acid Biosynthesis: Species-specific responses to species-specific deficiencies 7.3.2.4 Compatible solutes: a concomitant response in cryoenvironments 7.3.2.5 Membrane fluidity: A major role in the overall metabolic rate at temperature 7.3.2.6 The cell wall at low temperature: A poorly understood growth rate determinant 7.3.2.7 Transporters: The balance between local nutrient uptake and depletion 7.3.2.8 Genome plasticity. The potential role of transposases and repeated sequences. 7.4 Protein adaptations to cold 7.4.1 The low temperature challenge 7.4.2 The stability activity relationship 7.4.3 Structural features of cold adapted enzymes. 7.4.4 Hydrophobic interactions 7.4.5 Electrostatic interactions 7.4.5.1 Arginine 7.4.5.2 Acidic residues 7.4.6 Structural elements 7.4.6.1 -helices and -sheets 7.4.6.2 Proline and Glycine 7.4.6.3 Disordered regions 7.5 Comparison of cold- and warm-adapted Exiguobacterium strains 7.5.1 Phylogeny reflects adaptations to environmental conditions 7.5.2 Genomic comparison of two strains 7.6 Summary and future directions

Bakermans, Corien [Pennsylvania State University; Bergholz, Peter W. [Cornell University; Rodrigues, Debora F. [University of Houston, Houston; Vishnivetskaya, T. [University of Tennessee, Knoxville (UTK); Ayala-del-Ro, Hector L. [University of Puerto Rico; Tiedje, James M. [Michigan State University, East Lansing

2011-01-01T23:59:59.000Z

246

Adaptive control for energy conservation  

SciTech Connect

The objective of this project is to investigate the use of adaptive control concepts in buildings with solar-assisted heating, ventilating, and air-conditioning (HVAC) systems to maintain occupant comfort conditions while minimizing auxiliary energy use. Accomplishing this objective requires an energy management system capable of making sound tradeoffs. Optimal control theory is used along with a system identification technique to provide an adaptable stratgy. The resulting overall approach is known as adaptive optimal control (AOC).

Farris, D.R.

1980-03-01T23:59:59.000Z

247

Adaptive coherent interferometric imaging for sensor networks Gregoire Derveauxa)  

E-Print Network (OSTI)

with distributed sensor networks is presented. The sensors record the impulse response of the unknown background imaging when the background is known is considered in Ref.8. The sensors record an approximate impulseAdaptive coherent interferometric imaging for sensor networks Gr´egoire Derveauxa) INRIA Domaine de

Papanicolaou, George C.

248

Adaptive Restoration of Airborne Daedalus AADS1268 ATM Thermal Data  

SciTech Connect

To incorporate the georegistration and restoration processes into airborne data processing in support of U.S. Department of Energy's nuclear emergency response task, we developed an adaptive restoration filter for airborne Daedalus AADS1268 ATM thermal data based on the Wiener filtering theory. Preliminary assessment shows that this filter enhances the detectability of small weak thermal anomalies in AADS1268 thermal images.

D. Yuan; E. Doak; P. Guss; A. Will

2002-01-01T23:59:59.000Z

249

Mutual Inhibition Increases Adaptation Rate in an Electrosensory System 1  

E-Print Network (OSTI)

are the responses of MG cells to the sh's own electric organ discharge (EOD). Corollary discharge signals associated with the motor command that drives the EOD project to the ELL as parallel bers that terminate on apical dendrites of MG cells. Adaptation of MG cells to changes in EOD-evoked electrosensory patterns result from changes

Roberts, Patrick D.

250

Adaptive capacity and its assessment  

SciTech Connect

This paper reviews the concept of adaptive capacity and various approaches to assessing it, particularly with respect to climate variability and change. I find that adaptive capacity is a relatively under-researched topic within the sustainability science and global change communities, particularly since it is uniquely positioned to improve linkages between vulnerability and resilience research. I identify opportunities for advancing the measurement and characterization of adaptive capacity by combining insights from both vulnerability and resilience frameworks, and I suggest several assessment approaches for possible future development that draw from both frameworks and focus on analyzing the governance, institutions, and management that have helped foster adaptive capacity in light of recent climatic events.

Engle, Nathan L.

2011-04-20T23:59:59.000Z

251

Protein Structure Suggests Role as Molecular Adapter  

NLE Websites -- All DOE Office Websites (Extended Search)

Protein Structure Suggests Role Protein Structure Suggests Role as Molecular Adapter Protein Structure Suggests Role as Molecular Adapter Print Wednesday, 24 June 2009 00:00 To split and copy DNA during replication, all cellular organisms use a multicomponent molecular machine known as the replisome. An essential step in replisome assembly is the loading of ring-shaped helicases (motor proteins) onto the separated strands of DNA. Dedicated ATP-fueled proteins regulate the loading; however, the mechanism by which these proteins recruit and deposit helicases has remained unclear. To better understand this process, researchers at the University of California, Berkeley, recently determined the structure of the ATPase region of DnaC, a bacterial helicase loader. The structure revealed that DnaC is a close cousin of DnaA, the protein thought to be responsible for unwinding DNA. Unexpectedly, the team further found that DnaC forms a right-handed helix similar to the state adopted by ATP-bound DnaA. These findings, together with biochemical studies, implicate DnaC as a molecular adapter that uses ATP-activated DnaA as a docking site for ensuring that DnaB (the ring-shaped helicase) is correctly deposited at the onset of replication.

252

Emerging patterns of adaptive re-use : the new American House Hotel  

E-Print Network (OSTI)

This thesis aims to develop a design solution for the adaptive reuse of the American House Hotel that answers an architectural design challenge with technical responses. The process of actualization has been pushed a bit ...

Moody, Linda A

1984-01-01T23:59:59.000Z

253

Radiating gravastars  

SciTech Connect

Considering a Vaidya exterior spacetime, we study dynamical models of prototype gravastars, made of an infinitely thin spherical shell of a perfect fluid with the equation of state p = ?, enclosing an interior de Sitter spacetime. We show explicitly that the final output can be a black hole, an unstable gravastar, a stable gravastar or a 'bounded excursion' gravastar, depending on how the mass of the shell evolves in time, the cosmological constant and the initial position of the dynamical shell. This work presents, for the first time in the literature, a gravastar that emits radiation.

Chan, R. [Coordenao de Astronomia e Astrofsica, Observatrio Nacional, Rua General Jos Cristino, 77, So Cristvo 20921-400, Rio de Janeiro, RJ (Brazil); Silva, M.F.A. da [Departamento de Fsica Terica, Instituto de Fsica, Universidade do Estado do Rio de Janeiro, Rua So Francisco Xavier 524, Maracan 20550-900, Rio de Janeiro - RJ (Brazil); Rocha, Jaime F. Villas da [Instituto de Biocincias, Departamento de Cincias Naturais, Universidade Federal do Estado do Rio de Janeiro, Av. Pasteur 458, Urca, CEP 22290-240, Rio de Janeiro, RJ (Brazil); Wang, Anzhong, E-mail: chan@on.br, E-mail: mfasnic@gmail.com, E-mail: jfvroch@pq.cnpq.br, E-mail: anzhong_wang@baylor.edu [GCAP-CASPER, Department of Physics, Baylor University, Waco, TX 76798 (United States)

2011-10-01T23:59:59.000Z

254

BRIDGING NAVIGATION, SEARCH AND ADAPTATION. Adaptive Hypermedia Models Evolution  

E-Print Network (OSTI)

Corpus, Dexter Model, AHAM, GAF. Abstract: Adaptive Hypermedia Systems (AHS) have long been concentrating The most referenced (but certainly not only) Adaptive Hypermedia (AH) model dates back to 1999. Since AHAM/Hypermedia modelling from Dexter Model through AHAM to the proposed GAF model, out- line advantages of each framework

De Bra, Paul

255

Personalized video adaptation framework (PIAF): high-level semantic adaptation  

Science Journals Connector (OSTI)

Despite much work on Universal Multimedia Experience (UME), existing video adaptation approaches cannot yet be considered as truly user-centric, mostly due to their poor handling of semantic user preferences. Indeed, these works mainly concentrate on ... Keywords: MPEG-21, MPEG-7, Personalized video, Semantic adaptation, Semantic constraint, Universal multimedia experience

Vanessa El-Khoury, David Coquil, Nadia Bennani, Lionel Brunie

2014-05-01T23:59:59.000Z

256

Low Dose Radiation Research Program: About  

NLE Websites -- All DOE Office Websites (Extended Search)

About About Background. Extensive research on the health effects of radiation using standard epidemiological and toxicological approaches has been done for decades to characterize responses of populations and individuals to high radiation doses, and to set exposure standards to protect both the public and the workforce. These standards were set using models that extrapolated from the cancers observed following exposure to high doses of radiation to predicted, but not measurable, changes in cancer frequency at low radiation doses. The use of models was necessary because of our inability to detect changes in cancer incidence following low doses of radiation. Historically, the predominant approach has been the Linear-no-Threshold model (see Wikipedia entry) and collective dose concept that assumes each unit of radiation, no

257

Natural and Radiation Carcinogenesis in Man. III. Radiation Carcinogenesis  

Science Journals Connector (OSTI)

...mice. NATURAL AND RADIATION CARCINOGENESIS IN MAN. 3. RADIATION CARCINOGENESIS. | Journal Article | Japan Neoplasms etiology Neoplasms, Radiation-Induced Radiation Genetics | JAPAN NEOPLASM ETIOLOGY NEOPLASMS, RADIATION-INDUCED RADIATION...

1965-01-01T23:59:59.000Z

258

Lanthanum Halide Nanoparticle Scintillators for Nuclear Radiation Detection  

SciTech Connect

Nanoparticles with sizes <10 nm were fabricated and characterized for their nanocomposite radiation detector properties. This work investigated the properties of several nanostructured radiation scintillators, in order to determine the viability of using scintillators employing nanostructured lanthanum tribromide, lanthanum trifluoride, or cerium tribromide. Preliminary results of this investigation are consistent with the idea that these materials have an intrinsic response to nuclear radiation that may be correlated to the energy of the incident radiation.

Guss, P. P., Guise, R., Yuan, D., Mukhopadhyay, S., O'Brien, R., Lowe, D.

2013-02-01T23:59:59.000Z

259

FAQS Qualification Card - Radiation Protection | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Radiation Protection Radiation Protection FAQS Qualification Card - Radiation Protection A key element for the Department's Technical Qualification Programs is a set of common Functional Area Qualification Standards (FAQS) and associated Job Task Analyses (JTA). These standards are developed for various functional areas of responsibility in the Department, including oversight of safety management programs identified as hazard controls in Documented Safety Analyses (DSA). For each functional area, the FAQS identify the minimum technical competencies and supporting knowledge and skills for a typical qualified individual working in the area. FAQC-RadiationProtection.docx Description Radiation Protection Qualification Card More Documents & Publications FAQS Gap Analysis Qualification Card - Radiation Protection

260

Adaptive Medical Information Delivery Combining User, Task and Situation Models  

E-Print Network (OSTI)

., in their model for adaptive hypermedia AHAM [2], distinguish content­adaptation from link­ adaptation

Note: This page contains sample records for the topic "radiation adaptive responses" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


261

Introduction Adaptive LBM Realistic computations Conclusions A block-structured parallel adaptive Lattice-Boltzmann  

E-Print Network (OSTI)

Lattice-Boltzmann method for rotating geometries Ralf Deiterding & Stephen Wood+ Deutsches Zentrum f Conclusions Outline Introduction AMROC software Adaptive LBM Lattice Boltzmann method Structured adaptive mesh Introduction AMROC software Adaptive LBM Lattice Boltzmann method Structured adaptive mesh refinement

Deiterding, Ralf

262

Adaptation, Learning, and Optimization over  

E-Print Network (OSTI)

Adaptation, Learning, and Optimization over Networks Ali H. Sayed University of California at Los 2014 A. H. Sayed DOI: 10.1561/2200000051 Adaptation, Learning, and Optimization over Networks Ali H . . . . . . . . . . . . . . . . . . . . . . . . . 7 1.6 Notation and Symbols . . . . . . . . . . . . . . . . . . . . 8 2 Optimization by Single Agents

California at Los Angeles, University of

263

Organizational Adaptation Kathleen M. Carley  

E-Print Network (OSTI)

-humans. For example, they suggest that organizational learning resides not just in the minds of the personnel withinOrganizational Adaptation Kathleen M. Carley Dept. of Social and Decision Sciences Carnegie Mellon: Kathleen M. Carley, 1998, "Organizational Adaptation." Annals of Operations Research. 75: 25-47. #12

Sadeh, Norman M.

264

E-Print Network 3.0 - antioxidant response element-mediated Sample...  

NLE Websites -- All DOE Office Websites (Extended Search)

brake fern (Pteris vittata L.) upon... adaptive biochemical responses such as production of antioxidant ... Source: Ma, Lena - Soil and Water Science Department, University...

265

Radiation Safety  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Brotherhood of Locomotive Brotherhood of Locomotive Engineers & Trainmen Scott Palmer BLET Radiation Safety Officer New Hire Training New Hire study topics * GCOR * ABTH * SSI * Employee Safety * HazMat * Railroad terminology * OJT * 15-week class * Final test Hazardous Materials * Initial new-hire training * Required by OSHA * No specified class length * Open book test * Triennial module Locomotive Engineer Training A little bit older...a little bit wiser... * Typically 2-4 years' seniority * Pass-or-get-fired promotion * Intensive program * Perpetually tested to a higher standard * 20 Weeks of training * 15 of that is OJT * General Code of Operating Rules * Air Brake & Train Handling * System Special Instructions * Safety Instructions * Federal Regulations * Locomotive Simulators * Test Ride * Pass test with 90% Engineer Recertification

266

Low Dose Radiation Research Program: Genetic Factors Affecting  

NLE Websites -- All DOE Office Websites (Extended Search)

Affecting Susceptibility to Low-Dose Radiation Affecting Susceptibility to Low-Dose Radiation William F. Morgan Pacific Northwest National Laboratory Why This Project The short-term effects of high doses of ionizing radiation on cellular responses are relatively well understood. Less clear are the long-term consequences of exposure to low dose/low dose-rate radiation and the effects of radiation exposure on the progeny of surviving cells. If a cell survives radiation, it is generally thought to have repaired all the radiation-induced insults and be capable of a "normal healthy life". At a certain frequency, however, we have found that some cells surviving radiation grow normally, but will rearrange their genetic material during time in culture. We call this radiation-induced genomic instability. Many

267

Protein phosphorylation and regulation of adaptive responses in bacteria.  

Science Journals Connector (OSTI)

...a domain which is highly conserved in a large family of bacterial regulatory proteins...Escherichia coli. Sequence identification of the large subunit gene. FEBS Lett. 177:260-264...Kielland-Brandt, and G. R. Fink. 1986. Yeast plasma membrane ATPase is essential for growth...

J B Stock; A J Ninfa; A M Stock

1989-12-01T23:59:59.000Z

268

The AROUND project: Adapting robotic disaster response to developing countries  

E-Print Network (OSTI)

Reduction (WCDR) [20] stresses this necessity in points no 89 ("Advanced technologies for disaster reduction hazards. As a consequence, in cities like Hanoi, not only are disasters (floods, storms, cyclones, fires

Boyer, Edmond

269

Adaptive Response Surface Method Using Inherited Latin Hypercube Design Points  

E-Print Network (OSTI)

ARSM is tested using a group of standard test problems and then applied to an engineering design problem. In both testing and design application, significant improvement in the efficiency of ARSM and positive results have been achieved. Besides CCD, alphabetical optimal designs, especially D

Wang, Gaofeng Gary

270

Automated Grid Disruption Response System: Robust Adaptive Topology Control (RATC)  

SciTech Connect

GENI Project: The RATC research team is using topology control as a mechanism to improve system operations and manage disruptions within the electric grid. The grid is subject to interruption from cascading faults caused by extreme operating conditions, malicious external attacks, and intermittent electricity generation from renewable energy sources. The RATC system is capable of detecting, classifying, and responding to grid disturbances by reconfiguring the grid in order to maintain economically efficient operations while guaranteeing reliability. The RATC system would help prevent future power outages, which account for roughly $80 billion in losses for businesses and consumers each year. Minimizing the time it takes for the grid to respond to expensive interruptions will also make it easier to integrate intermittent renewable energy sources into the grid.

None

2012-03-01T23:59:59.000Z

271

Plant Response to Stress: Biochemical Adaptations to Phosphate Deficiency  

E-Print Network (OSTI)

, the world's reserves of rock Pi (mined for production of Pi fertilizers) are expected to be depleted within. In return, the host plant supplies sucrose to fuel the energy demands of the mycorrhizal symbiont Science DOI: 10.1081/E-EPCS 120010648 Copyright D 2004 by Marcel Dekker, Inc. All rights reserved. #12

Plaxton, William

272

Adaptable architecture : a computational exploration into responsive design systems  

E-Print Network (OSTI)

Based on the fact that architecture is, among other things, the crystallization of a mediation among design intentions (function), meaning and contextual constraints (performance), we as designers are obligated to produce ...

Zulas, Alejandro, 1976-

2004-01-01T23:59:59.000Z

273

Responsive Web and Adaptive Web for Open and Ubiquitous Learning  

Science Journals Connector (OSTI)

Online educational processes make use of different tools and platforms through which learning resources can be shared. Nowadays mobile platforms are gaining momentum and learners can experience mobile ubiquitous ...

Marco Mercurio; Ilaria Torre; Simone Torsani

2014-01-01T23:59:59.000Z

274

Direct detector for terahertz radiation  

DOE Patents (OSTI)

A direct detector for terahertz radiation comprises a grating-gated field-effect transistor with one or more quantum wells that provide a two-dimensional electron gas in the channel region. The grating gate can be a split-grating gate having at least one finger that can be individually biased. Biasing an individual finger of the split-grating gate to near pinch-off greatly increases the detector's resonant response magnitude over prior QW FET detectors while maintaining frequency selectivity. The split-grating-gated QW FET shows a tunable resonant plasmon response to FIR radiation that makes possible an electrically sweepable spectrometer-on-a-chip with no moving mechanical optical parts. Further, the narrow spectral response and signal-to-noise are adequate for use of the split-grating-gated QW FET in a passive, multispectral terahertz imaging system. The detector can be operated in a photoconductive or a photovoltaic mode. Other embodiments include uniform front and back gates to independently vary the carrier densities in the channel region, a thinned substrate to increase bolometric responsivity, and a resistive shunt to connect the fingers of the grating gate in parallel and provide a uniform gate-channel voltage along the length of the channel to increase the responsivity and improve the spectral resolution.

Wanke, Michael C. (Albuquerque, NM); Lee, Mark (Albuquerque, NM); Shaner, Eric A. (Albuquerque, NM); Allen, S. James (Santa Barbara, CA)

2008-09-02T23:59:59.000Z

275

African Adaptation Programme | Open Energy Information  

Open Energy Info (EERE)

Adaptation Programme Adaptation Programme Jump to: navigation, search Logo: African Adaptations Programme Name African Adaptations Programme Agency/Company /Organization United Nations Development Programme, Government of Japan Topics Adaptation, Finance, Implementation, Policies/deployment programs Website http://www.undp-adaptation.org References AAP[1] Overview "UNDP, with funding from the Government of Japan, recently launched a new programme that uses an innovative approach to climate change adaptation in Africa. Under this programme, UNDP will assist 21 African countries in implementing integrated and comprehensive adaptation actions and resilience plans. The projects will ensure that national development processes incorporate climate change risks and opportunities to secure development gains under a

276

Adaptive Materials Inc | Open Energy Information  

Open Energy Info (EERE)

Michigan Zip: MI 48108 Product: Adaptive Materials Inc (AMI) is a developer of portable fuel cell technology. References: Adaptive Materials Inc1 This article is a stub. You...

277

Energy Efficiency Limits of Load Adaptive Networks  

Science Journals Connector (OSTI)

Based on traffic models the energy consumption of adaptive networks is compared to networks with constant power consumption. The results show that adaptive network resource...

Lange, Christoph; Gladisch, Andreas

278

Management Responsibilities  

NLE Websites -- All DOE Office Websites (Extended Search)

Management Responsibilities Management Responsibilities Depleted UF6 Management Responsibilities DOE has responsibility for safe and efficient management of approximately 700,000 metric tons of depleted UF6. Organizational Responsibilities In the United States, the U.S. Department of Energy is responsible for managing all the depleted uranium that has been generated by the government and has been declared surplus to national defense needs. In addition, as a result of two memoranda of agreement that have been signed between the DOE and USEC, the DOE has assumed management responsibility for approximately 145,000 metric tons of depleted UF6 that has been or will be generated by USEC. Any additional depleted UF6 that USEC generates will be USEC's responsibility to manage. DOE Management Responsibility

279

Nuclear radiation electronic gear  

Science Journals Connector (OSTI)

Nuclear radiation electronic gear ... Examines the line of nuclear radiation instrumentation offered by Nuclear-Chicago Corporation and Victoreen Instrument Company. ... Nuclear / Radiochemistry ...

S. Z. Lewin

1961-01-01T23:59:59.000Z

280

WeADAPT | Open Energy Information  

Open Energy Info (EERE)

WeADAPT WeADAPT Jump to: navigation, search Name WeADAPT Agency/Company /Organization weADAPT Sector Energy, Land, Water, Climate Resource Type Training materials, Lessons learned/best practices Website http://www.weadapt.org/ References weADAPT[1] "weADAPT.org is an online 'open space' on climate adaptation issues (including the synergies between adaptation and mitigation) which allows practitioners, researchers and policy makers to access credible, high quality information and to share experiences and lessons learnt with the weADAPT community. It is designed to facilitate learning, exchange, collaboration and knowledge integration to build a professional community of practice on adaptation issues while developing policy-relevant tools and guidance for adaptation planning and decision-making.

Note: This page contains sample records for the topic "radiation adaptive responses" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


281

AfricaAdapt | Open Energy Information  

Open Energy Info (EERE)

AfricaAdapt AfricaAdapt Jump to: navigation, search Logo: Africa Adapt Name Africa Adapt Agency/Company /Organization AfricaAdapt Resource Type Training materials, Lessons learned/best practices Website http://www.africa-adapt.net/AA UN Region Eastern Africa, Middle Africa, Northern Africa, Southern Africa, Western Africa References AfricaAdapt[1] Abstract AfricaAdapt is an independent bilingual network (French/English) focused exclusively on Africa. The Network's aim is to facilitate the flow of climate change adaptation knowledge for sustainable livelihoods between researchers, policy makers, civil society organisations and communities who are vulnerable to climate variability and change across the continent. Africa Adapt Screenshot "AfricaAdapt is an independent bilingual network (French/English) focused

282

Low Dose Radiation Research Program: Universities  

NLE Websites -- All DOE Office Websites (Extended Search)

Universities Universities | Duke University | Loma Linda University | Northwestern University | University of Chicago | University of California Davis | Northwestern University University of Chicago University of California Davis Effects of Low Dose Irradiation on NF-κB Signaling Networks and Mitochondria Principal Investigator: Dr. Gayle Woloschak DOE Low Dose Research Program Projects Low dose-low dose rate irradiation leads to long term changes in numbers of mitochondria and mitochondrial genomes - Principal Investigator: Gayle Woloschak, Professor, Department of Radiation Oncology, Northwestern University, Chicago, IL, USA NF-κB-mediated pro-survival network in low dose radiation-induced adaptive protection - Principal Investigator: Jian Jian Li, Professor, Department of Radiation Oncology, University of California Davis, Davis,

283

Autonomous adaptive acoustic relay positioning  

E-Print Network (OSTI)

We consider the problem of maximizing underwater acoustic data transmission by adaptively positioning an autonomous mobile relay so as to learn and exploit spatial variations in channel performance. The acoustic channel ...

Cheung, Mei Yi, S.M. Massachusetts Institute of Technology

2013-01-01T23:59:59.000Z

284

Adaptive and Temporallydependent Document Filtering  

E-Print Network (OSTI)

Adaptive and Temporally­dependent Document Filtering een wetenschappelijke proeve op het gebied van . . . . . . . . . . . . . . . . . . . . . 1 1.2 Document Filtering . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 1.3 Filtering Filtering Track 57 5.1 What is TREC . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57 5

Arampatzis, Avi

285

Adaptive multiconfigurational wave functions  

SciTech Connect

A method is suggested to build simple multiconfigurational wave functions specified uniquely by an energy cutoff ?. These are constructed from a model space containing determinants with energy relative to that of the most stable determinant no greater than ?. The resulting ?-CI wave function is adaptive, being able to represent both single-reference and multireference electronic states. We also consider a more compact wave function parameterization (?+SD-CI), which is based on a small ?-CI reference and adds a selection of all the singly and doubly excited determinants generated from it. We report two heuristic algorithms to build ?-CI wave functions. The first is based on an approximate prescreening of the full configuration interaction space, while the second performs a breadth-first search coupled with pruning. The ?-CI and ?+SD-CI approaches are used to compute the dissociation curve of N{sub 2} and the potential energy curves for the first three singlet states of C{sub 2}. Special attention is paid to the issue of energy discontinuities caused by changes in the size of the ?-CI wave function along the potential energy curve. This problem is shown to be solvable by smoothing the matrix elements of the Hamiltonian. Our last example, involving the Cu{sub 2}O{sub 2}{sup 2+} core, illustrates an alternative use of the ?-CI method: as a tool to both estimate the multireference character of a wave function and to create a compact model space to be used in subsequent high-level multireference coupled cluster computations.

Evangelista, Francesco A., E-mail: francesco.evangelista@emory.edu [Department of Chemistry and Cherry L. Emerson Center for Scientific Computation, Emory University, Atlanta, Georgia 30322 (United States)

2014-03-28T23:59:59.000Z

286

Electricity Markets Meet the Home through Demand Response Lazaros Gkatzikis  

E-Print Network (OSTI)

Electricity Markets Meet the Home through Demand Response Lazaros Gkatzikis CERTH, University Hegde, Laurent Massouli´e Technicolor Paris Research Lab Paris, France Abstract-- Demand response (DR the alternative option of dynamic demand adaptation. In this direction, demand response (DR) programs provide

287

Low Dose Radiation Program: Radiation Biology and the Radiation Research  

NLE Websites -- All DOE Office Websites (Extended Search)

Biology and the Radiation Research Program Biology and the Radiation Research Program The Department of Energy (DOE) and its predecessor organizations, Energy Research and Development Agency (ERDA) and Atomic Energy Commission (AEC), always have been concerned about the health effects of ionizing radiation. Extensive research has been conducted under their sponsorship at all levels of biological organization from molecules to man. Over the past 60 years, studies using every type of radiation source have included exposure to both external radiation sources and to internally deposited radioactive materials. These exposures used different dose patterns and distributions delivered over a wide range of experimental times. This extensive research provided the basis for the new Low Dose Radiation Research Program, linking

288

Radiation Emergency Assistance Center / Training Site | National Nuclear  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation Emergency Assistance Center / Training Site | National Nuclear Radiation Emergency Assistance Center / Training Site | National Nuclear Security Administration Our Mission Managing the Stockpile Preventing Proliferation Powering the Nuclear Navy Emergency Response Recapitalizing Our Infrastructure Continuing Management Reform Countering Nuclear Terrorism About Us Our Programs Our History Who We Are Our Leadership Our Locations Budget Our Operations Media Room Congressional Testimony Fact Sheets Newsletters Press Releases Speeches Events Social Media Video Gallery Photo Gallery NNSA Archive Federal Employment Apply for Our Jobs Our Jobs Working at NNSA Blog Radiation Emergency Assistance Center / Training Site Home > About Us > Our Programs > Emergency Response > Responding to Emergencies > Consequence Management > Radiation Emergency Assistance

289

Radiative Heat Transfer between Neighboring Particles  

E-Print Network (OSTI)

The near-field interaction between two neighboring particles is known to produce enhanced radiative heat transfer. We advance in the understanding of this phenomenon by including the full electromagnetic particle response, heat exchange with the environment, and important radiative corrections both in the distance dependence of the fields and in the particle absorption coefficients. We find that crossed terms of electric and magnetic interactions dominate the transfer rate between gold and SiC particles, whereas radiative corrections reduce it by several orders of magnitude even at small separations. Radiation away from the dimer can be strongly suppressed or enhanced at low and high temperatures, respectively. These effects must be taken into account for an accurate description of radiative heat transfer in nanostructured environments.

Alejandro Manjavacas; F. Javier Garcia de Abajo

2012-01-26T23:59:59.000Z

290

Polymorphisms in DNA Repair Genes, Medical Exposure to Ionizing Radiation, and Breast Cancer Risk  

Science Journals Connector (OSTI)

...the role of DSB repair in response to low-dose radiation, particularly the range experienced by women from mammograms and other...breast cancer associated with exposure to low doses of ionizing radiation. Although we specifically designed our questionnaire...

Robert C. Millikan; Jon S. Player; Allan Rene deCotret; Chiu-Kit Tse; and Temitope Keku

2005-10-01T23:59:59.000Z

291

An Update on SURFRADThe GCOS Surface Radiation Budget Network for the Continental United States  

Science Journals Connector (OSTI)

The Surface Radiation budget (SURFRAD) network was developed for the United States in the middle 1990s in response to a growing need for more sophisticated in situ surface radiation measurements to support satellite system validation; numerical ...

John A. Augustine; Gary B. Hodges; Christopher R. Cornwall; Joseph J. Michalsky; Carlos I. Medina

2005-10-01T23:59:59.000Z

292

Polymorphisms in Apoptosis- and Proliferation-Related Genes, Ionizing Radiation Exposure, and Risk of Breast Cancer among U.S. Radiologic Technologists  

Science Journals Connector (OSTI)

...radiation and breast cancer dose-response relationship...controls and quantified radiation breast doses in the low-to-moderate range. (Cancer Epidemiol Biomarkers...Breast Cancer|SNPs|Ionizing radiation|Interaction|Radiobiological...

Alice J. Sigurdson; Parveen Bhatti; Michele M. Doody; Michael Hauptmann; Laura Bowen; Steven L. Simon; Robert M. Weinstock; Martha S. Linet; Marvin Rosenstein; Marilyn Stovall; Bruce H. Alexander; Dale L. Preston; Jeffrey P. Struewing; and Preetha Rajaraman

2007-10-01T23:59:59.000Z

293

Mutations in Global Regulators Lead to Metabolic Selection during Adaptation to Complex Environments  

SciTech Connect

Adaptation to ecologically complex environments can provide insights into the evolutionary dynamics and functional constraints encountered by organisms during natural selection. Unlike adaptation to a single limiting resource, adaptation to a new environment with abundant and varied resources can be difficult to achieve by small incremental changes since many mutations are required to achieve even modest gains in fitness. Since changing complex environments are quite common in nature, we investigated how such an epistatic bottleneck can be avoided to allow rapid adaptation. We show that adaptive mutations arise repeatedly in independently evolved populations in the context of greatly increased genetic and phenotypic diversity. We go on to show that weak selection requiring substantial metabolic reprogramming can be readily achieved by mutations in the global response regulator arcA and the stress response regulator rpoS. We identified 46 unique single-nucleotide variants of arcA and 18 mutations in rpoS, nine of which resulted in stop codons or large deletions, suggesting that a subtle modulation of ArcA function and knockouts of rpoS are largely responsible for the metabolic shifts leading to adaptation. These mutations allow a higher order metabolic selection that eliminates epistatic bottlenecks, which could occur when many changes would be required. Proteomic and carbohydrate analysis of adapting E. coli populations revealed an up-regulation of enzymes associated with the TCA cycle and amino acid metabolism and an increase in the secretion of putrescine. The overall effect of adaptation across populations is to redirect and efficiently utilize uptake and catabolism of abundant amino acids. Concomitantly, there is a pronounced spread of more ecologically limited strains that results from specialization through metabolic erosion. Remarkably, the global regulators arcA and rpoS can provide a one-step mechanism of adaptation to a novel environment, which highlights the importance of global resource management as a powerful strategy to adaptation.

Saxer, Gerda; Krepps, Michael D.; Merkley, Eric D.; Ansong, Charles; Kaiser, Brooke LD; Valovska, Marie-Thrse; Ristic, Nikola; Yeh, Ping T.; Prakash, Vittal; Leiser, Owen P.; Nakhleh, Luay; Gibbons, Henry S.; Kreuzer, Helen W.; Shamoo, Yousif

2014-12-11T23:59:59.000Z

294

Regional Water Management: Adapting to Uncertain Water  

E-Print Network (OSTI)

Regional Water Management: Adapting to Uncertain Water Supply and Demand Jim Schneider, Ph · How Nebraska manages water · Dealing with uncertain water supplies: adaptive management #12;Regional-wide, systematic approach · Flexible--Adaptive Management Adaptive Manageme nt #12;Integrated Water Management

Nebraska-Lincoln, University of

295

An Adaptive Optimal Control Design for a Bolus Chasing Computed Tomography Angiography  

E-Print Network (OSTI)

imaging quality and to reduce contrast dose and radiation exposure, an optimal adaptive bolus chasing controller is proposed and tested based on actual patient data. The controller estimates and predicts errors are mathematically quantified in terms of estimation errors. The test results not only support

Virginia Tech

296

radiation.p65  

Office of Legacy Management (LM)

5 5 United States Department of Energy This fact sheet explains the potential health hazards associated with the radioactive decay of uranium and other radioactive elements found in ore and mill tailings. Potential Health Hazards of Radiation Man-made sources of radiation, most notably from medical uses and consumer products, contribute to the remaining radiation dose that individuals receive. A few household products, including smoke detectors, micro- wave ovens, and color televisions, emit small amounts of radiation. For most people, the benefits from using such products far outweigh the radiation risks. Radiation Dose Radiation is measured in various units. Individuals who have been exposed to radiation have received a radiation dose. Radiation dose to people is expressed in

297

Low Dose Radiation Research Program: Original Research Program Plan  

NLE Websites -- All DOE Office Websites (Extended Search)

Original Research Program Plan Original Research Program Plan Biological Effects of Low Dose and Dose Rate Radiation Prepared for the Office of Biological and Environmental Research by The Low Dose Radiation Research Program Plan Subcommittee of the Biological and Environmental Research Advisory Committee. II. Table of Contents Face Page Table of Contents Executive Summary Introduction Program Outline Low Dose Radiation vs. Endogenous Oxidative Damage - The Same or Different? Key Question Description Decision Making Value Recommendations and Costs Understanding Biological Responses to Radiation And Endogenous Damage Key Question Description Decision Making Value Recommendations and Costs Thresholds for Low Dose Radiation - Fact or Fiction? Key Question Description Decision Making Value Recommendations and Costs

298

Radiation sensitive devices and systems for detection of radioactive materials and related methods  

DOE Patents (OSTI)

Radiation sensitive devices include a substrate comprising a radiation sensitive material and a plurality of resonance elements coupled to the substrate. Each resonance element is configured to resonate responsive to non-ionizing incident radiation. Systems for detecting radiation from a special nuclear material include a radiation sensitive device and a sensor located remotely from the radiation sensitive device and configured to measure an output signal from the radiation sensitive device. In such systems, the radiation sensitive device includes a radiation sensitive material and a plurality of resonance elements positioned on the radiation sensitive material. Methods for detecting a presence of a special nuclear material include positioning a radiation sensitive device in a location where special nuclear materials are to be detected and remotely interrogating the radiation sensitive device with a sensor.

Kotter, Dale K

2014-12-02T23:59:59.000Z

299

Radiation Protection and Safety Training | Environmental Radiation...  

NLE Websites -- All DOE Office Websites (Extended Search)

The objective of this course is to provide students with an introduction to the fundamentals of ionizing radiation protection and safety. The course curriculum combines...

300

Atmospheric Radiation Measurement Radiative Atmospheric Divergence...  

NLE Websites -- All DOE Office Websites (Extended Search)

radiation emitted by the earth. This instrument is onboard a European Union geostationary weather satellite launched in December 2005; it is collecting data over Niamey and the...

Note: This page contains sample records for the topic "radiation adaptive responses" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


301

Low Dose Radiation Research Program: Interaction between Tissue and  

NLE Websites -- All DOE Office Websites (Extended Search)

between Tissue and Cellular Stress Responses: Effect of between Tissue and Cellular Stress Responses: Effect of TGF-ß Depletion on Radiation-Induced p53 Response M.H. Barcellos-Hoff, S.A. Ravani, R.L. Henshall, K.B. Ewan, R.L. Warters,* B. Parvin Lawrence Berkeley National Laboratory *University of Utah One of the most widely studied cellular responses to radiation is the activation of the transcription factor, p53, whose abundance and action dictates individual cellular fate decisions regarding proliferation, differentiation and death. A cell's response to damage needs to be rapid. Thus, it is not surprising that the activation of the p53 stress response primarily involves post-translational changes in the p53 protein. Whereas intracellular radiation-induced mediators of p53 stability have been the subject of intense study, little is known about the extracellular factors

302

Training Adaptive Decision-Making.  

SciTech Connect

Adaptive Thinking has been defined here as the capacity to recognize when a course of action that may have previously been effective is no longer effective and there is need to adjust strategy. Research was undertaken with human test subjects to identify the factors that contribute to adaptive thinking. It was discovered that those most effective in settings that call for adaptive thinking tend to possess a superior capacity to quickly and effectively generate possible courses of action, as measured using the Category Generation test. Software developed for this research has been applied to develop capabilities enabling analysts to identify crucial factors that are predictive of outcomes in fore-on-force simulation exercises.

Abbott, Robert G.; Forsythe, James C.

2014-10-01T23:59:59.000Z

303

radiation.cdr  

Office of Legacy Management (LM)

Radiation-It's a Fact of Life Radiation-It's a Fact of Life It has been with us since the beginning of time. Everyone who has ever walked on this planet has been exposed to radiation. For the most part, nature is the largest source of exposure. It's in the air we breathe, the ground we walk on, and even the food we eat. The radiation we receive from all natural and some man-made sources is called "background radiation." The millirem (mrem) is a unit used for measuring radiation received by a person. The total average background for radiation received by people living in the United States is 360 millirem per year (mrem/yr), of which 300 mrem/yr is from natural sources, and 60 mrem/yr is man-made. Cosmic Radiation from the sun and stars Internal Radiation from naturally radioactive

304

E-Print Network 3.0 - assessing radiation feedbacks Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

content from the whole quarter Summary: . Overview 2. Solar radiation and the Greenhouse effect 3. Forcings and feedbacks 4. Who's responsible 5... . Overview 2. Solar...

305

Straddle Carrier Radiation Portal Monitoring  

SciTech Connect

U.S. Customs and Border Protection (CBP) is the primary enforcement agency protecting the nations ports of entry. CBP is enhancing its capability to interdict the illicit import of nuclear and radiological materials and devices that may be used by terrorists. Pacific Northwest National Laboratory (PNNL) is providing scientific and technical support to CBP in their goal to enable rapid deployment of nuclear and radiation detection systems at U. S. ports of entry to monitor 100% of the incoming international traffic and cargo while not adversely impacting the operations or throughput of the ports. The U.S. ports of entry include the following vectors: land border crossings, seaports, airports, rail crossings, and mail and express consignment courier facilities. U.S. Customs and Border Protection (CBP) determined that a screening solution was needed for Seaport cargo containers being transported by Straddle Carriers (straddle carriers). A stationary Radiation Portal Monitor (RPM) for Straddle Carriers (SCRPM) is needed so that cargo containers can be scanned while in transit under a Straddle Carrier. The Straddle Carrier Portal operational impacts were minimized by conducting a time-motion study at the Port, and adaptation of a Remotely Operated RPM (RO-RPM) booth concept that uses logical lighting schemes for traffic control, cameras, Optical Character Recognition, and wireless technology.

Andersen, Eric S.; Samuel, Todd J.; Mullen, O Dennis

2005-08-01T23:59:59.000Z

306

Plutonium radiation surrogate  

DOE Patents (OSTI)

A self-contained source of gamma-ray and neutron radiation suitable for use as a radiation surrogate for weapons-grade plutonium is described. The source generates a radiation spectrum similar to that of weapons-grade plutonium at 5% energy resolution between 59 and 2614 keV, but contains no special nuclear material and emits little .alpha.-particle radiation. The weapons-grade plutonium radiation surrogate also emits neutrons having fluxes commensurate with the gamma-radiation intensities employed.

Frank, Michael I. (Dublin, CA)

2010-02-02T23:59:59.000Z

307

Radiation Safety Work Control Form  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation Safety Work Control Form Radiation Safety Work Control Form (see instructions on pg-2) Rev July-2012 Area: Form #: Date: Preliminary Applicability Screen: (a) Will closing the beam line injection stoppers mitigate the radiological hazards introduced by the proposed work? Yes No (b) Can the closed state of the beam line injection stoppers be assured during the proposed work (ie., work does NOT involve injection stoppers or associated HPS)? Yes No If the answers to both questions are yes, the work can be performed safely under an SSRL RSWCF. If the answer to either question is no, then the work must be performed under a SPEAR3 RSWCF. Section 1: Description of work to be done, including date and time. (Person Responsible completes section)

308

Radiation hardness of si strip detectors with integrated coupling capacitors  

SciTech Connect

Si strip detectors with integrated coupling capacitors between diode and metallization and with separate bias resistors for each strip have been exposed to ionising radiation. Results from measurements of detector response before and after irradiation are presented.

Dijkstra, H.; Horisberger, R.; Hubbeling, L.; Maehlum, G.; Peisert, A.; Weilhammer, P.; Tuuva, T.; Evensen, L.

1989-02-01T23:59:59.000Z

309

Radiation Safety Program Annual Review  

E-Print Network (OSTI)

........................................................................10 AREA RADIATION SURVEYS AND CONTAMINATION CONTROL...........................................11.....................................................................................................13 RADIOACTIVE WASTE MANAGEMENT meetings of the Radiation Safety Committee where new users and uses of radioactive materials, radiation

Lyubomirsky, Ilya

310

Radiator Labs | Department of Energy  

NLE Websites -- All DOE Office Websites (Extended Search)

of steam buildings. Radiator Labs developed a mechanism that allows heating systems to control heat transfer at each radiator. The Radiator Labs design utilizes an...

311

The universal radiative transport equation  

E-Print Network (OSTI)

THE UNIVERSAL RADIATIVE TRANSPORT EQUATION Rudolph W.The Universal Radiative Transport Equation Rudolph W.The various radiative transport equations used in general

Preisendorfer, Rudolph W

1959-01-01T23:59:59.000Z

312

BC Agriculture Climate Change Adaptation  

E-Print Network (OSTI)

BC Agriculture Climate Change Adaptation Risk + Opportunity Assessment Provincial Report #12;published March 2012 by the British Columbia Agriculture & Food Climate Action Initiative www.BCAgClimateAction.ca project funding provided by Agriculture and Agri-food Canada BC Ministry of Agriculture BC Ministry

Pedersen, Tom

313

BC Agriculture Climate Change Adaptation  

E-Print Network (OSTI)

BC Agriculture Climate Change Adaptation Risk + Opportunity Assessment Provincial Report executive summary #12;published March 2012 by the British Columbia Agriculture & Food Climate Action Initiative www.BCAgClimateAction.ca project funding provided by Agriculture and Agri-food Canada BC Ministry of Agriculture BC Ministry

Pedersen, Tom

314

Adaptive wiener image restoration kernel  

DOE Patents (OSTI)

A method and device for restoration of electro-optical image data using an adaptive Wiener filter begins with constructing imaging system Optical Transfer Function, and the Fourier Transformations of the noise and the image. A spatial representation of the imaged object is restored by spatial convolution of the image using a Wiener restoration kernel.

Yuan, Ding (Henderson, NV)

2007-06-05T23:59:59.000Z

315

Investigating Intrusiveness of Workload Adaptation  

Science Journals Connector (OSTI)

In this paper, we investigate how an automatic task assistant which can detect and react to a user's workload level is able to support the user in a complex, dynamic task. In a user study, we design a dispatcher scenario with low and high workload conditions ... Keywords: brain computer interface, intrusiveness, user study, workload adaptive assistance

Felix Putze, Tanja Schultz

2014-11-01T23:59:59.000Z

316

Low Dose Radiation Research Program: Radiation-Induced Nuclear Factor kB  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation-Induced Nuclear Factor kB mediates survival advantage by Radiation-Induced Nuclear Factor kB mediates survival advantage by Telomerase Activation. Authors: Natarajan M.,1 Mohan S.,2 Pandeswara, S.L.,1 and Herman T.S.1 Institutions: Departments of 1Radiation Oncology and 2Pathology, The University of Texas Health Science Center, San Antonio, Texas Activation of NF-kB in response to low doses of ionizing radiation was first shown in our laboratory. Although studies have shown that NF-kB plays an important role in anti-apoptotic function, little has been done to understand the molecular link between the activation of NF-kB and cellular outcome such as enhanced cell survival after low dose low-linear transfer (LET) radiation. Because upregulation of telomerase activity is associated with longevity and allows cells to escape from senescence, we hypothesize

317

Radiation Dose Estimates from  

E-Print Network (OSTI)

Summary: Radiation Dose Estimates from Hanford Radioactive Material Releases to the Air- tantly, what radiation dose people may have received. An independent Technical Steering Panel (TSP, additionalProjectworkcouldresultin revisions of these dose estimates. April 21, 1994 Companion

318

Maryland Radiation Act (Maryland)  

Energy.gov (U.S. Department of Energy (DOE))

The policy of the state is to provide for the constructive use of radiation and control radiation emissions. This legislation authorizes the Department of the Environment to develop comprehensive...

319

WI Radiation Protection  

Energy.gov (U.S. Department of Energy (DOE))

This statute seeks to regulate radioactive materials, to encourage the constructive uses of radiation, and to prohibit and prevent exposure to radiation in amounts which are or may be detrimental...

320

Low Dose Radiation Research Program: National Laboratories  

NLE Websites -- All DOE Office Websites (Extended Search)

National Laboratories National Laboratories The Low Dose Radiation Program funding encompasses several Scientific Focus Areas (SFAs). The SFAs fund merit-reviewed research at DOE national laboratories. This management approach was created in 2008 by the Office of Biological and Environmental Research (BER) within the U.S. Department of Energy's (DOE's) Office of Science. PNNL's Low Dose Radiation Research Program Scientific Focus Area Linear and Nonlinear Tissue-Signaling Mechanisms in Response to Low Dose and Low Dose-Rate Radiation This program is funded as a U.S. Department of Energy Scientific Focus Area (SFA), and is an integrated cooperative program to understand low dose radiation effects in a complex model system. Coordinating Multidisciplinary Expertise The SFAs are designed to take advantage of the multidisciplinary,

Note: This page contains sample records for the topic "radiation adaptive responses" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


321

Radiative muon absorption in calcium  

Science Journals Connector (OSTI)

The photon spectrum from radiative absorption of negative muons in Ca40 has been measured with a high-resolution pair spectrometer. The data are analyzed in order to determine the induced pseudoscalar coupling constant gp in nuclear matter. When compared to models which use a realistic nuclear response function and avoid the closure approximation, a value of gp/gA=4.01.5 is obtained, which indicates a quenching of this coupling compared to the nucleonic value by a factor 0.570.25.

A. Frischknecht; W. Stehling; G. Strassner; P. Trul; J. C. Alder; C. Joseph; J. F. Loude; J. P. Perroud; D. Ruegger; T. M. Tran; W. Dahme; H. Panke; R. Kopp

1985-11-01T23:59:59.000Z

322

RADIONUCLIDE RADIATION PROTECTION  

E-Print Network (OSTI)

COPYRIGHT 2002 Nuclear Technology Publishing #12;3 #12;4 #12;5 Radiation Protection Dosimetry Vol. 98, No'Energie Atomique, CEA/Saclay, France ISBN 1 870965 87 6 RADIATION PROTECTION DOSIMETRY Vol. 98 No 1, 2002 Published by Nuclear Technology Publishing #12;RADIONUCLIDE AND RADIATION PROTECTION DATA HANDBOOK 2nd Edition (2002

Healy, Kevin Edward

323

Climate Change Adaptation Planning | Department of Energy  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

Change Adaptation Planning Climate Change Adaptation Planning October 7, 2014 6:00AM CDT to October 9, 2014 3:00PM CDT Norman, Oklahoma This course provides an introduction to...

324

Open questions regarding implications of radioadaptive response in the estimation of the risks of low-level exposures in nuclear workers  

Science Journals Connector (OSTI)

Substantial data indicate that increased levels of chromosome aberrations in lymphocytes can be used to predict cancer risk in humans. One may conclude that a dose of ionising radiation sufficient to produce a certain level of cell damage increases production of antioxidants and repair enzymes that decrease either the frequency of chromosome aberrations or the cancer risk. People in some areas of Ramsar, a city in northern Iran, receive an annual radiation dose from background radiation that is more than five times higher than the 20 mSv yr-1 that is permitted for radiation workers. If an annual radiation dose of a few hundred mSv is detrimental to health, causing genetic abnormalities or an increased risk of cancer, it should be evident in these people, while cytogenetic studies show no significant differences between people in the high background compared to people in normal background areas. Although there is not yet solid epidemiological information, most local physicians in Ramsar report anecdotally there is no increase in the incidence rates of cancer or leukemia in their area. On the other hand, there are no data to indicate a significant increase of cancer incidence in other High Background Radiation Areas (HBRAs) around the world. Furthermore, several studies show a significant decrease of cancer death rates in areas with high backgrounds. To assess the possible induction of an adaptive response, an in vitro challenge dose of 1.5 Gy of gamma rays was administered to the lymphocytes of the inhabitants as well as those of a neighbouring area. Lymphocytes of Ramsar residents showed a significantly reduced radiation sensitivity for chromosome aberrations compared to those of residents in normal background areas. Given the apparent lack of ill effects in the populations of these high dose-rate areas, these data further suggest that current dose limits are overly conservative.

S.M.J. Mortazavi; T. Ikushima

2006-01-01T23:59:59.000Z

325

E-Print Network 3.0 - adaptive systems Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

adaptive systems Page: << < 1 2 3 4 5 > >> 1 From Adaptive Hypermedia to the Adaptive Web Systems Summary: 1 From Adaptive Hypermedia to the Adaptive Web Systems Peter...

326

Brief Supervision of adaptive control algorithms  

Science Journals Connector (OSTI)

An adaptive controller needs supervisory functions in order to function well in an industrial environment. This paper describes these needs, and provides examples of supervisory functions that presently are used in industrial adaptive controllers. These ... Keywords: Adaptive control, Detection, Industrial control, Supervision

Tore HGglund; Karl Johan StrM

2000-08-01T23:59:59.000Z

327

Entropy Adaptive On-Line Compression  

Science Journals Connector (OSTI)

Self-Organization is based on adaptivity. Adaptivity should start with the very basic fundamental communication tasks such as encoding the information to be transmitted or stored. Obviously, the less signal transmitted the less energy in transmission ... Keywords: On-line compression, adaptive compression

Shlomi Dolev, Sergey Frenkel, Marina Kopeetsky

2014-08-01T23:59:59.000Z

328

Radioactivity and Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Radioactivity and Radiation Radioactivity and Radiation Uranium and Its Compounds line line What is Uranium? Chemical Forms of Uranium Properties of Uranium Compounds Radioactivity and Radiation Uranium Health Effects Radioactivity and Radiation Discussion of radioactivity and radiation, uranium and radioactivity, radiological health risks of uranium isotopes and decay products. Radioactivity Radioactivity is the term used to describe the natural process by which some atoms spontaneously disintegrate, emitting both particles and energy as they transform into different, more stable atoms. This process, also called radioactive decay, occurs because unstable isotopes tend to transform into a more stable state. Radioactivity is measured in terms of disintegrations, or decays, per unit time. Common units of radioactivity

329

TERSat: Trapped Energetic Radiation Satellite  

E-Print Network (OSTI)

Radiation damage caused by interactions with high-energy particles in the Van Allen Radiation Belts is a leading

Clements, Emily B.

2012-01-01T23:59:59.000Z

330

Americans' Average Radiation Exposure  

SciTech Connect

We live with radiation every day. We receive radiation exposures from cosmic rays, from outer space, from radon gas, and from other naturally radioactive elements in the earth. This is called natural background radiation. It includes the radiation we get from plants, animals, and from our own bodies. We also are exposed to man-made sources of radiation, including medical and dental treatments, television sets and emission from coal-fired power plants. Generally, radiation exposures from man-made sources are only a fraction of those received from natural sources. One exception is high exposures used by doctors to treat cancer patients. Each year in the United States, the average dose to people from natural and man-made radiation sources is about 360 millirem. A millirem is an extremely tiny amount of energy absorbed by tissues in the body.

NA

2000-08-11T23:59:59.000Z

331

Radiation: Facts, Risks and Realities  

E-Print Network (OSTI)

of Radiation 3 Understanding Radiation Risks 6 Naturally Occurring (Background) Radiation 7 Man-Made Radiation, beta particles and gamma rays. Other types, such as x-rays, can occur naturally or be machine-produced. Scientists have also learned that radiation sources are naturally all around us. Radiation can come from

332

Surface Radiation from GOES: A Physical Approach; Preprint  

SciTech Connect

Models to compute Global Horizontal Irradiance (GHI) and Direct Normal Irradiance (DNI) have been in development over the last 3 decades. These models can be classified as empirical or physical, based on the approach. Empirical models relate ground based observations with satellite measurements and use these relations to compute surface radiation. Physical models consider the radiation received from the earth at the satellite and create retrievals to estimate surface radiation. While empirical methods have been traditionally used for computing surface radiation for the solar energy industry the advent of faster computing has made operational physical models viable. The Global Solar Insolation Project (GSIP) is an operational physical model from NOAA that computes GHI using the visible and infrared channel measurements from the GOES satellites. GSIP uses a two-stage scheme that first retrieves cloud properties and uses those properties in a radiative transfer model to calculate surface radiation. NREL, University of Wisconsin and NOAA have recently collaborated to adapt GSIP to create a 4 km GHI and DNI product every 30 minutes. This paper presents an outline of the methodology and a comprehensive validation using high quality ground based solar data from the National Oceanic and Atmospheric Administration (NOAA) Surface Radiation (SURFRAD) (http://www.srrb.noaa.gov/surfrad/sitepage.html) and Integrated Surface Insolation Study (ISIS) http://www.srrb.noaa.gov/isis/isissites.html), the Solar Radiation Research Laboratory (SRRL) at National Renewable Energy Laboratory (NREL), and Sun Spot One (SS1) stations.

Habte, A.; Sengupta, M.; Wilcox, S.

2012-09-01T23:59:59.000Z

333

Genetic shift in photoperiodic response correlated with global warming  

E-Print Network (OSTI)

Genetic shift in photoperiodic response correlated with global warming William E. Bradshaw observed in insects, birds, amphibians, and plants associated with global warm- ing during the latter half- tent with an adaptive evolutionary response to recent global warming. The latter half of the 20th

Cochran-Stafira, D. Liane

334

Transcriptome Analysis Applied to Survival of Shewanella oneidensis MR-1 Exposed to Ionizing Radiation  

Science Journals Connector (OSTI)

...radiation (IR) dose that yields 20...its response to UV radiation (254 nm), which...sensitivity to IR. Ionizing radiation (IR) is potentially...damage caused by given doses of IR for different...similar, although the range of IR resistance...

Xiaoyun Qiu; Michael J. Daly; Alexander Vasilenko; Marina V. Omelchenko; Elena K. Gaidamakova; Liyou Wu; Jizhong Zhou; George W. Sundin; James M. Tiedje

2006-02-01T23:59:59.000Z

335

Low Dose Radiation Research Program: Linking Molecular Events to Cellular  

NLE Websites -- All DOE Office Websites (Extended Search)

Linking Molecular Events to Cellular Responses at Low Dose Exposures Linking Molecular Events to Cellular Responses at Low Dose Exposures Thomas Weber Pacific Northwest National Laboratory Why This Project It currently costs billions of dollars to protect workers and the public from exposure to man-made radiation, despite exposure levels lower than the natural background levels of radiation. If it could be demonstrated that there is no increased cancer risk associated with these low dose exposures, these resources could be directed toward more critical societal issues. Defining low dose radiation cancer risks is limited by our ability to measure and directly correlate relevant cellular and molecular responses occurring at the low radiation dose and dose rate with tumor formation. This deficiency has led to conservative risk assessments based on low dose

336

Adaptive Comfort Model: Simulations & Future Directions  

NLE Websites -- All DOE Office Websites (Extended Search)

Adaptive Comfort Model: Simulations & Future Directions Adaptive Comfort Model: Simulations & Future Directions Speaker(s): Richard de Dear Date: February 4, 2011 - 12:00pm Location: 90-4133 Seminar Host/Point of Contact: Philip Haves The last 20 years of thermal comfort have witnessed a shift away from the "static" approach (exemplified by the PMV/PPD model) towards the adaptive approach (exemplified by the adaptive models in ASHRAE's Standard 55 (2004, 2010) and the European Union's counterpart standard, EN15251 (2007). - the basis and derivation of the adaptive comfort model - adaptive comfort standards (ASHRAE 55 and EN15251) - new developments and directions (reporting back from the January 2011 ASHRAE Meeting of SSPC-55 in Las Vegas) - environmental variables other than dry bulb, in the adaptive model

337

The structural characteristics of radiation oncology in Japan in 2003  

Science Journals Connector (OSTI)

Purpose: To ascertain the basic structural characteristics of radiation oncology facilities in Japan, we conducted a national survey on their status in 2003. The aims of the survey included the following: present status of radiation treatment facilities, equipment, personnel, patient loads, and other factors. Methods and Materials: A mail survey verified each potential facility delivering megavoltage radiation therapy and collected data on treatment devices, other equipment, personnel, new patients, and so on. Responses were obtained from 100% of potential facilities. Results: A total of 726 facilities delivered radiation therapy, with 859 megavoltage devices, 203 RALS (remote after-loading system) and other radioactive sources, with 941 FTE (full-time employee) radiation oncologists including 369 FTE Japanese Society of Therapeutic Radiation Oncology-certified radiation oncologists, 1555 FTE radiation therapists, and 70 FTE physicists in 2003. Megavoltage devices included two heavy ion units and four proton units. In total, there were 149,793 new patients and 146,351 (98%) by external irradiation; 4379 (3%) were treated by brachytherapy with or without external irradiation. Eighty-six percent of the facilities had treatment-planning computers, but 4% had no treatment-planning capability. Six percent (44 facilities) of all facilities used hyperthermia, 12% (85 facilities) intraoperative radiation therapy, and 2% (12 facilities) intensity-modulated radiation therapy. Conclusion: Facilities surveys continue to provide a source of census data on radiation oncology in Japan, allowing comparisons among facility groups and over time.

Hitoshi Shibuya; Hirohiko Tsujii

2005-01-01T23:59:59.000Z

338

The structural characteristics of radiation oncology in Japan in 2003  

SciTech Connect

Purpose: To ascertain the basic structural characteristics of radiation oncology facilities in Japan, we conducted a national survey on their status in 2003. The aims of the survey included the following: present status of radiation treatment facilities, equipment, personnel, patient loads, and other factors. Methods and Materials: A mail survey verified each potential facility delivering megavoltage radiation therapy and collected data on treatment devices, other equipment, personnel, new patients, and so on. Responses were obtained from 100% of potential facilities. Results: A total of 726 facilities delivered radiation therapy, with 859 megavoltage devices, 203 RALS (remote after-loading system) and other radioactive sources, with 941 FTE (full-time employee) radiation oncologists including 369 FTE Japanese Society of Therapeutic Radiation Oncology-certified radiation oncologists, 1555 FTE radiation therapists, and 70 FTE physicists in 2003. Megavoltage devices included two heavy ion units and four proton units. In total, there were 149,793 new patients and 146,351 (98%) by external irradiation; 4379 (3%) were treated by brachytherapy with or without external irradiation. Eighty-six percent of the facilities had treatment-planning computers, but 4% had no treatment-planning capability. Six percent (44 facilities) of all facilities used hyperthermia, 12% (85 facilities) intraoperative radiation therapy, and 2% (12 facilities) intensity-modulated radiation therapy. Conclusion: Facilities surveys continue to provide a source of census data on radiation oncology in Japan, allowing comparisons among facility groups and over time.

Shibuya, Hitoshi [JASTRO Database Committee, Department of Radiology, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo (Japan)]. E-mail: shibuya.mrad@tmd.ac.jp; Tsujii, Hirohiko [National Institute of Radiological Sciences, Chiba-shi, Chiba (Japan)

2005-08-01T23:59:59.000Z

339

Center for Adaptive Optics* Santa Cruz,CA  

E-Print Network (OSTI)

Center for Adaptive Optics* Santa Cruz,CA The Center for Adaptive Optics (CfAO) will concentrate on astronomical and vision science applications of adaptive optics and will reach out to other adaptive optics communities to share technologies. It will develop new instruments optimized for adaptive optics. Adaptive

Grether, Gregory

340

Does the Entire Uterus Need to be Treated in Cancer of the Cervix? Role of Adaptive Brachytherapy  

SciTech Connect

Purpose: To evaluate local control and toxicity by use of a method of adaptive cervical brachytherapy (ACB). Methods and Materials: From 1998 to 2008, we identified 65 cervical cancer patients with FIGO (International Federation of Gynecology and Obstetrics) Stage IB1-IVA disease who received definitive external beam radiation therapy and high-dose rate brachytherapy with tandem and ovoid applicators. As tumors regressed, 45 of 65 patients had the tandem source retracted from the uterine fundus at successive brachytherapy insertions, thus decreasing the number of {sup 192}Ir dwell positions. Tests of trend and Fisher's exact test were used to identify the effect of ACB on disease control and toxicity. Kaplan-Meier analyses were performed to evaluate disease control and late complications. Results: The median follow-up was 24.5 months. Of the patients, 92% received chemotherapy. The 3-year overall survival, 3-year disease-free survival, 3-year distant metastasis-free survival, and local control rates were 67%, 76%, 79%, and 97%, respectively. There was only 1 isolated local failure, and there were no local failures beyond 1 year. Distant failure was involved in 93% of recurrences. No significant trend was identified regarding the extent of retraction of the tandem source start position with either failure or toxicity. Acute and actuarial 3-year late Grade 3 toxicity or greater occurred in 24.6% and 17% of patients, respectively. Conclusions: ACB determined by clinical response yielded excellent local control rates. These data indicate that ACB may be useful in decreasing late toxicities from high-dose rate brachytherapy. With the advent of three-dimensional image-guided brachytherapy, additional methods to adapt treatment technique to changes in tumor volume warrant investigation.

Anker, Christopher J.; Cachoeira, Charles V.; Boucher, Kenneth M.; Rankin, Jim M.S. [Department of Radiation Oncology, Huntsman Cancer Hospital, University of Utah, Salt Lake City, UT (United States); Gaffney, David K., E-mail: david.gaffney@hci.utah.ed [Department of Radiation Oncology, Huntsman Cancer Hospital, University of Utah, Salt Lake City, UT (United States)

2010-03-01T23:59:59.000Z

Note: This page contains sample records for the topic "radiation adaptive responses" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


341

Stanford Synchrotron Radiation Lightsource  

NLE Websites -- All DOE Office Websites (Extended Search)

Structure of the DUF2233 Domain in Bacteria and the Stuttering-associated UCE Glycoprotein July 2013 SSRL Science Summary (adapted from SLAC News Feature by Glennda Chui) Figure...

342

Radiation physics, biophysics, and radiation biology  

SciTech Connect

Research at the Center for Radiological Research is a multidisciplenary blend of physics, chemistry and biology aimed at understanding the mechanisms involved in the health problems resulting from human exposure to ionizing radiations. The focus is increased on biochemistry and the application of the techniques of molecular biology to the problems of radiation biology. Research highlights of the program from the past year are described. A mathematical model describing the production of single-strand and double-strand breaks in DNA as a function radiation quality has been completed. For the first time Monte Carlo techniques have been used to obtain directly the spatial distribution of DNA moieties altered by radiation. This information was obtained by including the transport codes a realistic description of the electronic structure of DNA. We have investigated structure activity relationships for the potential oncogenicity of a new generation of bioreductive drugs that function as hypoxic cytotoxins. Experimental and theoretical investigation of the inverse dose rate effect, whereby medium LET radiations actually produce an c effect when the dose is protracted, is now at a point where the basic mechanisms are reasonably understood and the complex interplay between dose, dose rate and radiation quality which is necessary for the effect to be present can now be predicted at least in vitro. In terms of early radiobiological damage, a quantitative link has been established between basic energy deposition and locally multiply damaged sites, the radiochemical precursor of DNA double strand breaks; specifically, the spatial and energy deposition requirements necessary to form LMDs have been evaluated. For the first time, a mechanically understood biological fingerprint'' of high-LET radiation has been established. Specifically measurement of the ratio of inter-to intra-chromosomal aberrations produces a unique signature from alpha-particles or neutrons.

Hall, E.J.; Zaider, M.

1993-05-01T23:59:59.000Z

343

Climate Change Basics: Science, Adaptation, & Mitigation  

E-Print Network (OSTI)

is Radiative Imbalance, Anthropogenic Big. #12;But, Feedbacks are Important! The most powerful greenhouse gas

Fox-Kemper, Baylor

344

Atmospheric Radiation Measurement Program  

NLE Websites -- All DOE Office Websites (Extended Search)

3 3 ARM 2003 Tom Ackerman Chief Scientist Tom Ackerman Chief Scientist ARM ARM Atmospheric Radiation Measurement Atmospheric Radiation Measurement WARNING! WARNING! Today is April 1 But that has NO bearing on this message Today is April 1 But that has NO bearing on this message ARM ARM Atmospheric Radiation Measurement Atmospheric Radiation Measurement Two Topics Two Topics * Status of ARM (quick overview) * Science plan - ARM in the next 5 years * Status of ARM (quick overview) * Science plan - ARM in the next 5 years ARM ARM Atmospheric Radiation Measurement Atmospheric Radiation Measurement ARM Status - Science ARM Status - Science * Steadily increasing productivity - Poster session - over 220 posters (may need to do something about submissions next year) - Peer-reviewed articles: 2.5 to 3 per year per

345

The flying radiation case  

SciTech Connect

The Los Alamos foil implosion program has the goal of producing an intense, high-energy density x-ray source by converting the energy of a magnetically imploded plasma into radiation and material energy. One of the methods for converting the plasma energy into thermal energy and radiation and utilizing it for experiments is called the flying radiation case (FRC). In this paper the authors shall model the FRC and provide a physical description of the processes involved. An analytic model of a planar FRC in the hydrodynamic approximation is used to describe the assembly and shock heating of a central cushion by a conducting liner driver. The results are also used to benchmark a hydrodynamics code for modeling an FRC. They then use a radiation-hydrodynamics computational model to explore the effects of radiation production and transport when a gold plasma assembles on a CH cushion. Results are presented for the structure and evolution of the radiation hohlraum.

Brownell, J.H.; Bowers, R.L. [Los Alamos National Lab., NM (United States). Applied Theoretical and Computational Physics Div.

1997-04-01T23:59:59.000Z

346

Low Dose Radiation Research Program: 2003 Molecular Characterization of the  

NLE Websites -- All DOE Office Websites (Extended Search)

Characterization of the Roles of SOD Genes in Mammalian Characterization of the Roles of SOD Genes in Mammalian Cellular Response to Low Dose Radiation Authors: Chuan-Yuan Li,1 Eric Chuang2 Institutions: 1Dept of Radiation Oncology, Duke University Medical Center, Durham, NC, 2Advanced Technology Center, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland The potential risks of exposure to low dose radiation are of major concerns to the DOE/OBER Low Dose Radiation Research Program. It has been long recognized that much of the radiation-induced genetic damage to cells are caused by secondary oxidative species. Therefore, internal cellular defense systems against oxidative stress play significant roles in countering genetic damage induced by ionizing radiation. The role of the detoxifying

347

Low Dose Radiation Research Program: Molecular Characterization of the  

NLE Websites -- All DOE Office Websites (Extended Search)

Molecular Characterization of the Roles of SOD Genes in Mammalian Molecular Characterization of the Roles of SOD Genes in Mammalian Cellular Response to Low Dose Radiation Authors: Chuan-Yuan Li, Zhanjun Guo, Zhonghui Yang, and Eric Chuang Institutions: Dept of Radiation Oncology, Duke University Medical Center, Durham, NC Advanced Technology Center, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland Background The potential risks of exposure to low dose radiation are of major concerns to the DOE/OBER Low Dose Radiation Research Program. It has been long recognized that much of the radiation-induced genetic damage to cells are caused by secondary oxidative species. Therefore internal cellular defense systems against oxidative stress play significant roles in countering genetic damage induced by ionizing radiation. The role of the detoxifying

348

Atomic Radiation (Illinois)  

Energy.gov (U.S. Department of Energy (DOE))

This article states permissible levels of radiation in unrestricted areas, environmental standards for uranium fuel cycle and information about notification of incidents.

349

Radiation.cdr  

NLE Websites -- All DOE Office Websites (Extended Search)

An average American's exposure is about 620 millirems per year from naturally occurring and other sources. Other Factors Background radiation varies with location....

350

Radiation Hazards Program (Minnesota)  

Energy.gov (U.S. Department of Energy (DOE))

These regulations, promulgated by the Department of Health, set allowable radiation standards and mitigation practices, as well as procedures for the transportation of hazardous material.

351

Radiation Safety September 2013  

E-Print Network (OSTI)

...................................................................................... 8 2.6 RUA Holder........................................................................................................ 11 3.3 Radiation Use Authorization (RUA).......................................................................................... 11 3.4 Review of RUA Applications

California at Irvine, University of

352

Radiative polarization of electrons  

Science Journals Connector (OSTI)

We present a new method of calculating the radiative polarization of electrons in homogeneous magnetic fields, using the modified electron propagation function.

Julian Schwinger and Wu-yang Tsai

1974-03-15T23:59:59.000Z

353

Measuring plasma turbulence using low coherence microwave radiation  

SciTech Connect

Low coherence backscattering (LCBS) is a proposed diagnostic technique for measuring plasma turbulence and fluctuations. LCBS is an adaptation of optical coherence tomography, a biomedical imaging technique. Calculations and simulations show LCBS measurements can achieve centimeter-scale spatial resolution using low coherence microwave radiation. LCBS measurements exhibit several advantages over standard plasma turbulence measurement techniques including immunity to spurious reflections and measurement access in hollow density profiles. Also, LCBS is scalable for 1-D profile measurements and 2-D turbulence imaging.

Smith, D. R. [Department of Engineering Physics, University of Wisconsin-Madison, Madison, Wisconsin 53706 (United States)

2012-02-20T23:59:59.000Z

354

ORISE: Radiation Emergency Assistance Center/Training Site (REAC/TS)  

NLE Websites -- All DOE Office Websites (Extended Search)

How ORISE is Making a Difference How ORISE is Making a Difference Overview CBL International Exercise Emergency Response Training International Training RANET Asset CBL BioDoseNet CBL's Empire 09 Support NASA Support International Partnerships Resources Overview Frequently Asked Questions about Radiation Understanding Radiation Video Series The Medical Aspects of Radiation Incidents Dose Estimates and Compendia Procedure Demonstrations for Contaminated Patients Hospital Triage Article Radiation Treatment Medication Package Inserts Cytogenetic Biodosimetry Laboratory Video Cytogenetic Biodosimetry Laboratory Brochure Dose Coefficients for Intakes of Radionuclides via Contaminated Wounds How to Work With Us Contact Us Featured Resources The Medical Aspects of Radiation Incidents The Medical Aspects of Radiation Incidents

355

Appendix F. Radiation Appendix F. Radiation F-3  

E-Print Network (OSTI)

from natural and human-made sources. People are exposed to naturally occurring radiation constantlyAppendix F. Radiation #12;#12;Appendix F. Radiation F-3 Appendix F. Radiation This appendix presents basic facts about radiation. The information is intended to be a basis for understanding

Pennycook, Steve

356

Appendix F: Radiation Appendix F: Radiation F-3  

E-Print Network (OSTI)

. People are exposed to naturally occurring radiation constantly. For example, cosmic radiation; radon effects on the environment and biological systems. Radiation comes from natural and human-made sourcesAppendix F: Radiation #12;#12;Appendix F: Radiation F-3 P P P E E E N NN HYDROGEN ATOM DEUTERIUM

Pennycook, Steve

357

Appendix F: Radiation Appendix F: Radiation F-3  

E-Print Network (OSTI)

to naturally occurring radiation constantly. For example, cosmic radiation; radon in air; potassium in food on the environment and biological systems. Radiation comes from natural and human-made sources. People are exposedAppendix F: Radiation #12;#12;Appendix F: Radiation F-3 Fig. F.1. The hydrogen atom and its

Pennycook, Steve

358

Appendix G. Radiation Appendix G. Radiation G-3  

E-Print Network (OSTI)

from natural and human-made sources. People are exposed to naturally occurring radiation constantlyAppendix G. Radiation #12;#12;Appendix G. Radiation G-3 Appendix G. Radiation This appendix presents basic facts about radiation. The information is intended to be a basis for un- derstanding

Pennycook, Steve

359

Appendix F. Radiation Appendix F. Radiation F-3  

E-Print Network (OSTI)

from natural and human-made sources. People are exposed to naturally occurring radiation constantlyAppendix F. Radiation #12;#12;Appendix F. Radiation F-3 Appendix F. Radiation This appendix presents basic facts about radiation. The information is intended to be a basis for un- derstanding

Pennycook, Steve

360

Radiation physics, biophysics, and radiation biology  

SciTech Connect

The following research programs from the Center for Radiological Research of Columbia University are described: Design and development of a new wall-less ultra miniature proportional counter for nanodosimetry; some recent measurements of ionization distributions for heavy ions at nanometer site sizes with a wall-less proportional counter; a calculation of exciton energies in periodic systems with helical symmetry: application to a hydrogen fluoride chain; electron energy-loss function in polynucleotide and the question of plasmon excitation; a non-parametric, microdosimetric-based approach to the evaluation of the biological effects of low doses of ionizing radiation; high-LET radiation risk assessment at medium doses; high-LET radiobiological effects: increased lesion severity or increased lesion proximity; photoneutrons generated by high energy medical linacs; the biological effectiveness of neutrons; implications for radiation protection; molecular characterization of oncogenes induced by neutrons; and the inverse dose-rate effect for oncogenic transformation by charged particles is LET dependent.

Hall, E.J.

1992-05-01T23:59:59.000Z

Note: This page contains sample records for the topic "radiation adaptive responses" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


361

Issues in adaptive mesh refinement  

SciTech Connect

In this paper, we present an approach for a patch-based adaptive mesh refinement (AMR) for multi-physics simulations. The approach consists of clustering, symmetry preserving, mesh continuity, flux correction, communications, and management of patches. Among the special features of this patch-based AMR are symmetry preserving, efficiency of refinement, special implementation offlux correction, and patch management in parallel computing environments. Here, higher efficiency of refinement means less unnecessarily refined cells for a given set of cells to be refined. To demonstrate the capability of the AMR framework, hydrodynamics simulations with many levels of refinement are shown in both two- and three-dimensions.

Dai, William Wenlong [Los Alamos National Laboratory

2009-01-01T23:59:59.000Z

362

Research priorities for occupational radiation protection  

SciTech Connect

The Subpanel on Occupational Radiation Protection Research concludes that the most urgently needed research is that leading to the resolution of the potential effects of low-level ionizing radiation. This is the primary driving force in setting appropriate radiation protection standards and in directing the emphasis of radiation protection efforts. Much has already been done in collecting data that represents a compendium of knowledge that should be fully reviewed and understood. It is imperative that health physics researchers more effectively use that data and apply the findings to enhance understanding of the potential health effects of low-level ionizing radiation and improve the risk estimates upon which current occupational radiation protection procedures and requirements depend. Research must be focused to best serve needs in the immediate years ahead. Only then will we get the most out of what is accomplished. Beyond the above fundamental need, a number of applied research areas also have been identified as national priority issues. If effective governmental focus is achieved on several of the most important national priority issues, important occupational radiation protection research will be enhanced, more effectively coordinated, and more quickly applied to the work environment. Response in the near term will be enhanced and costs will be reduced by: developing microprocessor-aided {open_quotes}smart{close_quotes} instruments to simplify the use and processing of radiation data; developing more sensitive, energy-independent, and tissue-equivalent dosimeters to more accurately quantify personnel dose; and developing an improved risk assessment technology base. This can lead to savings of millions of dollars in current efforts needed to ensure personnel safety and to meet new, more stringent occupational guidelines.

Not Available

1994-02-01T23:59:59.000Z

363

Adaptive management: a paradigm for remediation of public facilities  

SciTech Connect

Public facility restoration planning traditionally focused on response to natural disasters and hazardous materials accidental releases. These plans now need to integrate response to terrorist actions. Therefore, plans must address a wide range of potential vulnerabilities. Similar types of broad remediation planning are needed for restoration of waste and hazardous material handling areas and facilities. There are strong similarities in damage results and remediation activities between unintentional and terrorist actions; however, the uncertainties associated with terrorist actions result in a re-evaluation of approaches to planning. Restoration of public facilities following a release of a hazardous material is inherently far more complex than in confined industrial settings and has many unique technical, economic, social, and political challenges. Therefore, they arguably involve a superset of drivers, concerns and public agencies compared to other restoration efforts. This superset of conditions increases complexity of interactions, reduces our knowledge of the initial conditions, and even condenses the timeline for restoration response. Therefore, evaluations of alternative restoration management approaches developed for responding to terrorist actions provide useful knowledge for large, complex waste management projects. Whereas present planning documents have substantial linearity in their organization, the 'adaptive management' paradigm provides a constructive parallel operations paradigm for restoration of facilities that anticipates and plans for uncertainty, multiple/simUltaneous public agency actions, and stakeholder participation. Adaptive management grew out of the need to manage and restore natural resources in highly complex and changing environments with limited knowledge about causal relationships and responses to restoration actions. Similarities between natural resource management and restoration of a facility and surrounding area(s) after a disruptive event suggest numerous advantages over preset linearly-structured plans by incorporating the flexibility and overlap of processes inherent in effective facility restoration. We discuss three restoration case studies (e.g., the Hart Senate Office Building anthrax restoration, Rocky Flats actinide remediation, and hurricane destruction restoration), that implement aspects of adaptive management but not a formal approach. We propose that more formal adoption of adaptive management principles could be a basis for more flexible standards to improve site-specific remediation plans under conditions of high uncertainty.

Janecky, David R [Los Alamos National Laboratory; Whicker, Jeffrey J [Los Alamos National Laboratory; Doerr, Ted B [NON LANL

2009-01-01T23:59:59.000Z

364

Response Elements  

Directives, Delegations, and Requirements

The Guide provides acceptable methods for meeting the requirement of DOE O 151.1C for response elements that respond or contribute to response as needed in an emergency. Cancels DOE G 151.1-1, Volume 3-1, DOE G 151.1-1, Volume 3-2, DOE G 151.1-1, Volume 3-3, DOE G 151.1-1, Volume 3-4, DOE G 151.1-1, Volume 4-1, DOE G 151.1-1, Volume 4-2, DOE G 151.1-1, Volume 4-3, DOE G 151.1-1, Volume 4-4, DOE G 151.1-1, Volume 4-5, and DOE G 151.1-1, Volume 4-6.

2007-07-11T23:59:59.000Z

365

Longitudinal Investigation of Adaptive Functioning Following Conformal Irradiation for Pediatric Craniopharyngioma and Low-Grade Glioma  

SciTech Connect

Purpose: Children treated for brain tumors with conformal radiation therapy experience preserved cognitive outcomes. Early evidence suggests that adaptive functions or independent-living skills may be spared. This longitudinal investigation prospectively examined intellectual and adaptive functioning during the first 5 years following irradiation for childhood craniopharyngioma and low-grade glioma (LGG). The effect of visual impairment on adaptive outcomes was investigated. Methods and Materials: Children with craniopharyngioma (n=62) and LGG (n=77) were treated using conformal or intensity modulated radiation therapy. The median age was 8.05 years (3.21-17.64 years) and 8.09 years (2.20-19.27 years), respectively. Serial cognitive evaluations including measures of intelligence quotient (IQ) and the Vineland Adaptive Behavior Scales (VABS) were conducted at preirradiation baseline, 6 months after treatment, and annually through 5 years. Five hundred eighty-eight evaluations were completed during the follow-up period. Results: Baseline assessment revealed no deficits in IQ and VABS indices for children with craniopharyngioma, with significant (P<.05) longitudinal decline in VABS Communication and Socialization indices. Clinical factors associated with more rapid decline included females and preirradiation chemotherapy (interferon). The only change in VABS Daily Living Skills correlated with IQ change (r=0.34; P=.01) in children with craniopharyngioma. Children with LGG performed below population norms (P<.05) at baseline on VABS Communication, Daily Living Indices, and the Adaptive Behavior Composite, with significant (P<.05) longitudinal decline limited to VABS Communication. Older age at irradiation was a protective factor against longitudinal decline. Severe visual impairment did not independently correlate with poorer adaptive outcomes for either tumor group. Conclusions: There was relative sparing of postirradiation functional outcomes over time in this sample. Baseline differences in functional abilities before the initiation of irradiation suggested that other factors influence functional outcomes above and beyond the effects of irradiation.

Netson, Kelli L. [Department of Psychiatry and Behavioral Sciences, Kansas University School of MedicineWichita, Kansas (United States)] [Department of Psychiatry and Behavioral Sciences, Kansas University School of MedicineWichita, Kansas (United States); Conklin, Heather M. [Department of Psychology, St Jude Children's Research Hospital, Memphis, Tennessee (United States)] [Department of Psychology, St Jude Children's Research Hospital, Memphis, Tennessee (United States); Wu, Shengjie; Xiong, Xiaoping [Department of Biostatistics, St Jude Children's Research Hospital, Memphis, Tennessee (United States)] [Department of Biostatistics, St Jude Children's Research Hospital, Memphis, Tennessee (United States); Merchant, Thomas E., E-mail: thomas.merchant@stjude.org [Division of Radiation Oncology, St Jude Children's Research Hospital, Memphis, Tennessee (United States)

2013-04-01T23:59:59.000Z

366

COLUMBIA UNIVERSITY Radiation Safety Program  

E-Print Network (OSTI)

DDE ESTIMATED DOSE FROM CONCEPTION TO DECLARATION: DDE Radiation Safety Officer Signature for increased protection from ionizing radiation for declared pregnant radiation workers. The radiation dose of the occupational dose limit of 50 mSv (5.0 rem). The CPMC Radiation Safety Office will provide education

Jia, Songtao

367

RADIATION ONCOLOGY TARGET YOUR FUTURE  

E-Print Network (OSTI)

. · Radiation therapist - a health professional who designs, calculates (plans) and provides the radiation dose and monitors the delivery of radiation therapy, taking into account the protection and safety of patientsRADIATION ONCOLOGY TARGET YOUR FUTURE #12;A Career in Radiation Oncology YOUR CHOICE SAVE LIVES

Tobar, Michael

368

Y-12 Opens New NNSA Alarm Response Training Academy | National...  

National Nuclear Security Administration (NNSA)

Response Training Program has been in operation for more than five years and has helped train some 3,400 on-site radiation safety and security personnel, local law enforcement...

369

Adaptive Robust Control of Programmable Valves with Manufacturer Supplied Flow Mapping Only  

E-Print Network (OSTI)

and final tracking accuracy. In addition, real-time adaptation is used to reduce the degree of modelling-in and meter-out orifices [2], [3], [4] through valves number 1,2 and 4,5; and ii) enabling the precise control is the significant modelling error. The cartridge valves are of fast response and low cost but low accuracy

Yao, Bin

370

An Adaptive Cartesian Detonation Solver for Fluid-Structure Interaction Simulation on Distributed Memory Computers  

E-Print Network (OSTI)

An Adaptive Cartesian Detonation Solver for Fluid-Structure Interaction Simulation on Distributed shock and detonation waves impinging on deforming solid structures benefit significantly from) for studying the three- dimensional dynamic response of solid materials subject to strong shock and detonation

371

Climate Change Adaptation New Perspectives for Natural Resource Management and Conservation1  

E-Print Network (OSTI)

Climate Change Adaptation New Perspectives for Natural Resource Management and Conservation1 Institute of Food and Agricultural Sciences February 2012 A Changing Climate for Conservation Climate change species of plants and animals are already shifting their distributions in response to climate change

Mazzotti, Frank

372

Radiation safety system  

Science Journals Connector (OSTI)

......occupational illness to personnel, major damage...acceptable levels. Selection of control measures...or equipment operating correctly in...99 103 to 104 Personnel life safety...and abnormal operating conditions under...radiation risk to personnel, public and...worker radiation training) reduces the......

Vaclav Vylet; James C. Liu; Lawrence S. Walker

2009-11-01T23:59:59.000Z

373

Radiation safety system  

Science Journals Connector (OSTI)

......disable this safety function and...circuits and software. Other required...source in case of radiation monitors. Feedback...from other non-safety systems to prevent...write and check software. The expected...logic systems for safety functions can...levels of prompt radiation hazard. ACS......

Vaclav Vylet; James C. Liu; Lawrence S. Walker

2009-11-01T23:59:59.000Z

374

Risks from ionizing radiation  

Science Journals Connector (OSTI)

... RADON indoors now accounts for nearly half of the average UK population exposure to ionizing radiation ... exposure to ionizing radiation. We believe that the extent of the variation in exposure to radon in the United Kingdom and else-where and its magnitude in relation to exposures from ...

R. H. Clarke; T. R. E. Southwood

1989-03-16T23:59:59.000Z

375

Nuclear radiation actuated valve  

DOE Patents (OSTI)

A nuclear radiation actuated valve for a nuclear reactor. The valve has a valve first part (such as a valve rod with piston) and a valve second part (such as a valve tube surrounding the valve rod, with the valve tube having side slots surrounding the piston). Both valve parts have known nuclear radiation swelling characteristics. The valve's first part is positioned to receive nuclear radiation from the nuclear reactor's fuel region. The valve's second part is positioned so that its nuclear radiation induced swelling is different from that of the valve's first part. The valve's second part also is positioned so that the valve's first and second parts create a valve orifice which changes in size due to the different nuclear radiation caused swelling of the valve's first part compared to the valve's second part. The valve may be used in a nuclear reactor's core coolant system.

Christiansen, David W. (Kennewick, WA); Schively, Dixon P. (Richland, WA)

1985-01-01T23:59:59.000Z

376

Forecasting with adaptive extended exponential smoothing  

Science Journals Connector (OSTI)

Much of product level forecasting is based upon time series techniques. However, traditional time series forecasting techniques have offered either smoothing constant adaptability or consideration of various t...

John T. Mentzer Ph.D.

377

ChapterTitle ADAPTIVE EXPONENTIAL SMOOTHING  

Science Journals Connector (OSTI)

The single exponential smoothing forecasting model requires the specification of a ... ?, which determines the degree of model smoothing. Proper selection of the coefficient ? is...adaptive exponential smoothing,...

2000-01-01T23:59:59.000Z

378

Training for Climate Adaptation in Conservation  

Energy.gov (U.S. Department of Energy (DOE))

The Wildlife Conservation Society and the Northern Institute of Applied Climate Science are hosting this two-day training for climate adaptation.

379

Assessing Climate Change Impacts, Vulnerability and Adaptation...  

Open Energy Info (EERE)

The Case of Pantabangan-Carranglan Watershed Jump to: navigation, search Name Assessing Climate Change Impacts, Vulnerability and Adaptation: The Case of Pantabangan-Carranglan...

380

Mainstreaming Climate Change Adaptation into Development Planning...  

Open Energy Info (EERE)

Practitioners Jump to: navigation, search Tool Summary LAUNCH TOOL Name: Mainstreaming Climate Change Adaptation into Development Planning: A Guide for Practitioners Agency...

Note: This page contains sample records for the topic "radiation adaptive responses" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


381

Machine Learning for Adaptive Computer Game Opponents .  

E-Print Network (OSTI)

??This thesis investigates the use of machine learning techniques in computer games to create a computer player that adapts to its opponent's game-play. This includes (more)

Miles, Jonathan David

2009-01-01T23:59:59.000Z

382

Adaptive Barrier Strategies for Nonlinear Interior Methods  

E-Print Network (OSTI)

Feb 25, 2005 ... that adaptive choices, such as Mehrotra's probing procedure, outperform ... focus on the effects of merit functions or filters, and on regularization...

2005-02-25T23:59:59.000Z

383

Crosscutting Subsurface Initiative: Adaptive Control of Subsurface...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

in the ability to access, characterize, predict, and adaptively manipulate fracture and flow processes over scales from nanometers to kilometers. This town hall...

384

2014 DOE Climate Change Adaptation Plan  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

systems face increasing risks from shifting disease vectors, temperature increases and health care system infrastructure from a changing climate DOE Climate Change Adaptation...

385

Radiation Weighting Factors and High Energy Radiation  

Science Journals Connector (OSTI)

......generally inadequate for high energy radiation. In order to determine...appropriate wR values in the high energy region, several criteria are...are proposed for neutrons of energy above 100 MeV and for protons above 10 MeV. The wR value for muons is confirmed to be practically......

M. Pelliccioni

1998-12-01T23:59:59.000Z

386

Promoting a functional and comparative understanding of the conifer genome- implementing applied aspects for more productive and adapted forests (ProCoGen)  

Science Journals Connector (OSTI)

In the midst of a climatic change scenario, the genetics of adaptive response in conifers becomes essential to ensure a sustainable management of genetic resources and an effective breeding. Conifers are the targ...

Carmen Daz-Sala; Teresa Cervera

2011-09-01T23:59:59.000Z

387

Radiation effects on humans  

NLE Websites -- All DOE Office Websites (Extended Search)

Radiation effects on humans Radiation effects on humans Name: Joe Kemna Location: N/A Country: N/A Date: N/A Question: I am trying to find information on radiation. I need the effects on humans, the damage it causes to the environment, and any extra information you might have on the subject. Thank you for your time. Replies: Your library should be a good place to start, but first you need to narrow your question a bit. "Radiation" means radio waves, heat, light (including the ultraviolet light that causes suntan and sunburn), and what's called "ionizing radiation." By far the major source of the first three is the Sun, while the last I believe comes principally from cosmic rays and various naturally radioactive elements like uranium and radon. The most significant manmade sources of exposure would --- I think --- be household wiring and appliances (radio), engines and heating devices (heat), lamps (light), and X-ray machines, flying at high altitude in airplanes, and living in well-insulated homes built over radon sources (ionizing radiation). Heat, light and ionizing radiation play vital roles in the ecology of the Earth. Radio, light (in particular "tanning" ultraviolet), and ionizing radiation have all been widely assumed at different times to be particularly good or particularly bad for human health. Some recent issues of public concern have been the effect of radio waves from electric transmission lines, the effect on skin cancer incidence from tanning and sunburns, the depletion of the ultraviolet-light-produced ozone in the upper atmosphere by chlorofluorocarbons (CFCs), "global warming" from the increased absorption of heat radiation from the surface by atmospheric carbon dioxide and methane, and the effect of a long exposure to low levels of ionizing radiation as for example the people of Eastern Europe are experiencing from the Chernobyl nuclear power plant accident.

388

Differential Role of Transcription-Coupled Repair in UVBInduced Response of Human Fibroblasts and Keratinocytes  

Science Journals Connector (OSTI)

...Cancer Institute, Rome, Italy Most solar radiation-induced skin cancers...cellular components by the higher-energy shorter solar wavelengths comprising the UVB spectra...learn more about the response to solar radiation of the target cells for...

Mariarosaria D'Errico; Massimo Teson; Angelo Calcagnile; Tiziana Nardo; Naomi De Luca; Chiara Lazzari; Silvia Soddu; Giovanna Zambruno; Miria Stefanini; and Eugenia Dogliotti

2005-01-15T23:59:59.000Z

389

Candidate Radiation Drugs Inch Forward  

Science Journals Connector (OSTI)

Candidate Radiation Drugs Inch Forward 10.1126/science.331.6024...radiation, workers at the damaged Fukushima nuclear plant wear protective gear...Candidate radiation drugs inch forward. | News | 0 (E)-4-carboxystyryl-4-chlorobenzylsulfone...

Yudhijit Bhattacharjee

2011-03-25T23:59:59.000Z

390

EOLSS ADAPTATIONS TO LIFE IN MARINE CAVES PAGE 1 ADAPTATIONS TO LIFE IN MARINE CAVES  

E-Print Network (OSTI)

EOLSS ­ ADAPTATIONS TO LIFE IN MARINE CAVES PAGE 1 ADAPTATIONS TO LIFE IN MARINE CAVES Thomas M. Iliffe, Department of Marine Biology, Texas A&M University at Galveston, USA Renée E. Bishop, Department, biodiversity, ecology, adaptation, evolution, behavior, conservation, endangered species, cave diving

Iliffe, Thomas M.

391

High resolution amorphous silicon radiation detectors  

DOE Patents (OSTI)

A radiation detector employing amorphous Si:H cells in an array with each detector cell having at least three contiguous layers (n type, intrinsic, p type), positioned between two electrodes to which a bias voltage is applied. An energy conversion layer atop the silicon cells intercepts incident radiation and converts radiation energy to light energy of a wavelength to which the silicon cells are responsive. A read-out device, positioned proximate to each detector element in an array allows each such element to be interrogated independently to determine whether radiation has been detected in that cell. The energy conversion material may be a layer of luminescent material having a columnar structure. In one embodiment a column of luminescent material detects the passage therethrough of radiation to be detected and directs a light beam signal to an adjacent a-Si:H film so that detection may be confined to one or more such cells in the array. One or both electrodes may have a comb structure, and the teeth of each electrode comb may be interdigitated for capacitance reduction. The amorphous Si:H film may be replaced by an amorphous Si:Ge:H film in which up to 40 percent of the amorphous material is Ge. Two dimensional arrays may be used in X-ray imaging, CT scanning, crystallography, high energy physics beam tracking, nuclear medicine cameras and autoradiography.

Street, Robert A. (Palo Alto, CA); Kaplan, Selig N. (El Cerrito, CA); Perez-Mendez, Victor (Berkeley, CA)

1992-01-01T23:59:59.000Z

392

High resolution amorphous silicon radiation detectors  

DOE Patents (OSTI)

A radiation detector employing amorphous Si:H cells in an array with each detector cell having at least three contiguous layers (n-type, intrinsic, p-type), positioned between two electrodes to which a bias voltage is applied. An energy conversion layer atop the silicon cells intercepts incident radiation and converts radiation energy to light energy of a wavelength to which the silicon cells are responsive. A read-out device, positioned proximate to each detector element in an array allows each such element to be interrogated independently to determine whether radiation has been detected in that cell. The energy conversion material may be a layer of luminescent material having a columnar structure. In one embodiment a column of luminescent material detects the passage therethrough of radiation to be detected and directs a light beam signal to an adjacent a-Si:H film so that detection may be confined to one or more such cells in the array. One or both electrodes may have a comb structure, and the teeth of each electrode comb may be interdigitated for capacitance reduction. The amorphous Si:H film may be replaced by an amorphous Si:Ge:H film in which up to 40 percent of the amorphous material is Ge. Two dimensional arrays may be used in X-ray imaging, CT scanning, crystallography, high energy physics beam tracking, nuclear medicine cameras and autoradiography. 18 figs.

Street, R.A.; Kaplan, S.N.; Perez-Mendez, V.

1992-05-26T23:59:59.000Z

393

Alpha-beta radiation detector  

DOE Patents (OSTI)

The invention is based in part on the discovery that a plastic housing that is lightweight is surprisingly efficient inasmuch as background signals from any gamma radiation are significantly reduced by using a plastic housing instead of a metal housing. A further aspect of the present invention is the profile of the housing as a bi-linear approximation to a parabola resulting in full optical response from any location on the scintillation material to the photomultiplier tube. A yet further aspect of the present invention is that the survey probe is resistant to magnetic fields. A yet further aspect of the present invention is the use of a snap-fit retaining bracket that overcomes the need for multiple screws.

Fleming, Dale M. (Richland, WA); Simmons, Kevin L. (Kennewick, WA); Froelich, Thomas J. (West Richland, WA); Carter, Gregory L. (Richland, WA)

1998-01-01T23:59:59.000Z

394

RADIATIVE TRANSFER IN ULTRARELATIVISTIC OUTFLOWS  

SciTech Connect

Analytical and numerical solutions are obtained for the equation of radiative transfer in ultrarelativistic opaque jets. The solution describes the initial trapping of radiation, its adiabatic cooling, and the transition to transparency. Two opposite regimes are examined. (1) Matter-dominated outflow. Surprisingly, radiation develops enormous anisotropy in the fluid frame before decoupling from the fluid. The radiation is strongly polarized. (2) Radiation-dominated outflow. The transfer occurs as if radiation propagated in vacuum, preserving the angular distribution and the blackbody shape of the spectrum. The escaping radiation has a blackbody spectrum if (and only if) the outflow energy is dominated by radiation up to the photospheric radius.

Beloborodov, Andrei M., E-mail: amb@phys.columbia.edu [Physics Department and Columbia Astrophysics Laboratory, Columbia University, 538 West 120th Street New York, NY 10027 (United States)

2011-08-20T23:59:59.000Z

395

Radiation prevents much cancer  

Science Journals Connector (OSTI)

Evidence reviewed here supports the concept that chronic exposure to ionising radiation can dramatically decrease cancer incidence and mortality. This evidence includes an inverse relationship between radiation levels and cancer induction and/or mortality in: over 200 million people in the USA; 200 million people in India; 10,000 residents of Taipei who live in cobalt-60 contaminated homes; high radiation areas of Ramsar, Iran; 12 million person-years of exposed and carefully selected control nuclear workers; almost 300,000 homes with radon in the USA; non-smokers in high radon areas of Saxony, Germany.

T.D. Luckey

2007-01-01T23:59:59.000Z

396

Biophysics and synchrotron radiation  

SciTech Connect

This book, contains contributions to the conference on Biophysics and Synchrotron Radiation held in July 1986 at Frascati. It is devoted to advances in the resolution of biological molecule structure obtainable through synchroton radiation studies. The use of synchroton radiation has firmly established x-ray spectroscopy of biological molecules. More detailed knowledge on the local structure of active sites of metalloproteins, as well as a number of studies on the interaction of metal ions with other important biological macromolecular systems are presented. This new method for protein structure analysis is a major improvement for the rapidly expanding field of protein engineering.

Bianconi, A.; Castellano, C.C.

1987-01-01T23:59:59.000Z

397

Miniaturized radiation chirper  

DOE Patents (OSTI)

The disclosure relates to a miniaturized radiation chirper for use with a small battery supplying on the order of 5 volts. A poor quality CdTe crystal which is not necessarily suitable for high resolution gamma ray spectroscopy is incorporated with appropriate electronics so that the chirper emits an audible noise at a rate that is proportional to radiation exposure level. The chirper is intended to serve as a personnel radiation warning device that utilizes new and novel electronics with a novel detector, a CdTe crystal. The resultant device is much smaller and has much longer battery life than existing chirpers.

Umbarger, C. John (Los Alamos, NM); Wolf, Michael A. (Los Alamos, NM)

1980-01-01T23:59:59.000Z

398

Composition for radiation shielding  

DOE Patents (OSTI)

A composition for use as a radiation shield. The shield has a depleted urum core for absorbing gamma rays and a bismuth coating for preventing chemical corrosion and absorbing gamma rays. Alternatively, a sheet of gadolinium may be positioned between the uranium core and the bismuth coating for absorbing neutrons. The composition is preferably in the form of a container for storing materials that emit radiation such as gamma rays and neutrons. The container is preferably formed by casting bismuth around a pre-formed uranium container having a gadolinium sheeting, and allowing the bismuth to cool. The resulting container is a structurally sound, corrosion-resistant, radiation-absorbing container.

Kronberg, James W. (Aiken, SC)

1994-01-01T23:59:59.000Z

399

The Intense Radiation Gas  

E-Print Network (OSTI)

We present a new dispersion relation for photons that are nonlinearly interacting with a radiation gas of arbitrary intensity due to photon-photon scattering. It is found that the photon phase velocity decreases with increasing radiation intensity, it and attains a minimum value in the limit of super-intense fields. By using Hamilton's ray equations, a self-consistent kinetic theory for interacting photons is formulated. The interaction between an electromagnetic pulse and the radiation gas is shown to produce pulse self-compression and nonlinear saturation. Implications of our new results are discussed.

M. Marklund; P. K. Shukla; B. Eliasson

2005-03-08T23:59:59.000Z

400

Rights-based evaluation of government responses to a given 'natural' disaster : Katrina as case study  

E-Print Network (OSTI)

Disaster impacts human mobility and a rights-based approach to disaster response is needed to protect the human rights of those who seek migration as an adaptation strategy. This paper deals with returning to a place after ...

Haeffner, Melissa (Melissa Ann)

2010-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "radiation adaptive responses" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


401

Adaptive Port Reduction in Static Condensation  

E-Print Network (OSTI)

Adaptive Port Reduction in Static Condensation JL Eftang DBP Huynh DJ Knezevic EM Rønquist a framework for adaptive reduction of the degrees of freedom associated with ports in static condensation (SC reduction for the interior of a component with model order reduction on the ports in order to rapidly

Rønquist, Einar M.

402

Adaptive Composite Map Projections Bernhard Jenny  

E-Print Network (OSTI)

Adaptive Composite Map Projections Bernhard Jenny Abstract--All major web mapping services use.The proposed composite map projection combines several projections that are recommended in cartographic.The composite projection adapts the maps geometry to scale, to the maps height-to-width ratio

Jenny, Bernhard

403

Outreach and Adaptive Strategies for Climate Change  

E-Print Network (OSTI)

Outreach and Adaptive Strategies for Climate Change: The Role of NOAA Sea Grant Extension years and generations about how to adapt to a changing climate. Effective preparation for possible effects of climate change includes engagement of resource managers, planners, public works officials

404

A fuzzy-tuned adaptive Kalman filter  

E-Print Network (OSTI)

In this paper, fuzzy processing is applied to the adaptive Kalman filter. The filter gain coefficients are adapted over a 50 dB range of unknown signal/noise dynamics, using fuzzy membership functions. Specific simulation results are shown for a...

Painter, John H.; Young Hwan Lho

1993-12-01T23:59:59.000Z

405

WORKLOAD ADAPTATION IN AUTONOMIC DATABASE MANAGEMENT SYSTEMS  

E-Print Network (OSTI)

in Autonomic DBMSs", Proceedings of the 2nd International Workshop on Self-Managing Database Systems (SMDB 2007 to meet its Service Level Objectives (SLOs). It is a challenge to adapt multiple workloads with complex scheduler that performs workload adaptation in a DBMS, as the test bed to prove the effectiveness

406

Proceedings of the International Workshop on Adaptation,  

E-Print Network (OSTI)

Proceedings of the 1st International Workshop on Adaptation, Personalization and REcommendation. Carrero3 1 Universidad Autónoma de Madrid, Spain {ivan.cantador, david.vallet}@uam.es 2 Yahoo! Research.carrero}@uem.es #12;#12;Preface The 1st International Workshop on Adaptation, Personalization and REcommendation

Cantador, Iván

407

Adaptive computations on conforming quadtree meshes  

Science Journals Connector (OSTI)

In this paper, the quadtree data structure and conforming polygonal interpolants are used to develop an h-adaptive finite element method. Quadtree is a hierarchical data structure that is computationally attractive for adaptive numerical simulations. ... Keywords: Barycentric coordinates, Hanging nodes, Laplace interpolant, Meshfree methods, Natural neighbors, Quadtree data structure

A. Tabarraei; N. Sukumar

2005-04-01T23:59:59.000Z

408

Safety implementation of adaptive embedded control components  

Science Journals Connector (OSTI)

The paper deals with dynamic reconfigurations of component-based adaptive embedded control systems to be automatically handled at run-time by intelligent agents. We define a Control Component as a software unit supporting control tasks of the system ... Keywords: adaptive embedded control system, dynamic reconfiguration, intelligent agent, semaphore, software control component

Atef Gharbi; Mohamed Khalgui; Samir Ben Ahmed

2011-09-01T23:59:59.000Z

409

Adaptive performance support for fault diagnosis  

Science Journals Connector (OSTI)

This paper introduces a strategy, a user model, and a methodology for utilising adaptive hypermedia in performance support domain and specifically for fault diagnosis. This utilisation is implemented by employing task-specific and user-centred hypermedia ... Keywords: adaptive hypermedia, diagnostic expert systems, performance support systems, semantic data modelling, user modelling

Ammar M. Huneiti

2008-07-01T23:59:59.000Z

410

Creating Adaptive Feedback designed for Improving Data Entry Accuracy  

E-Print Network (OSTI)

Abstract- Data quality is a critical problem in modern databases. Data-entry forms present the first and arguably best opportunity for detecting and mitigating errors, but there has been little research into automatic methods for improving data quality at entry time. In this paper, we propose USHER, an end-to-end system for form design, entry, and data quality assurance. Using previous form submissions, USHER learns a probabilistic model over the questions of the form. USHER then applies this model at every step of the data-entry process to improve data quality. Before entry, it induces a form layout that captures the most important data values of a form instance as quickly as possible and reduces the complexity of error-prone questions. During entry, it dynamically adapts the form to the values being entered by providing real-time interface feedback, reasking questions with dubious responses, and simplifying questions by reformulating them. After entry, it revisits question responses that it deems likely to have been entered incorrectly by reasking the question or a reformulation thereof. We evaluate these components of USHER using two real-world data sets. Our results demonstrate that USHER can improve data quality considerably at a reduced cost when compared to current practice. Index Terms- Data quality, data entry, form design, adaptive form. O I.

P. Jaya Prakash; B. Venkateswarlu; S. Abdul Jeelan; Assistant Professors; Andhra Pradesh-india

411

Method and apparatus for measuring spatial uniformity of radiation  

DOE Patents (OSTI)

A method and apparatus for measuring the spatial uniformity of the intensity of a radiation beam from a radiation source based on a single sampling time and/or a single pulse of radiation. The measuring apparatus includes a plurality of radiation detectors positioned on planar mounting plate to form a radiation receiving area that has a shape and size approximating the size and shape of the cross section of the radiation beam. The detectors concurrently receive portions of the radiation beam and transmit electrical signals representative of the intensity of impinging radiation to a signal processor circuit connected to each of the detectors and adapted to concurrently receive the electrical signals from the detectors and process with a central processing unit (CPU) the signals to determine intensities of the radiation impinging at each detector location. The CPU displays the determined intensities and relative intensity values corresponding to each detector location to an operator of the measuring apparatus on an included data display device. Concurrent sampling of each detector is achieved by connecting to each detector a sample and hold circuit that is configured to track the signal and store it upon receipt of a "capture" signal. A switching device then selectively retrieves the signals and transmits the signals to the CPU through a single analog to digital (A/D) converter. The "capture" signal. is then removed from the sample-and-hold circuits. Alternatively, concurrent sampling is achieved by providing an A/D converter for each detector, each of which transmits a corresponding digital signal to the CPU. The sampling or reading of the detector signals can be controlled by the CPU or level-detection and timing circuit.

Field, Halden (Boulder, CO)

2002-01-01T23:59:59.000Z

412

Demand Response and Open Automated Demand Response  

E-Print Network (OSTI)

LBNL-3047E Demand Response and Open Automated Demand Response Opportunities for Data Centers G described in this report was coordinated by the Demand Response Research Center and funded by the California. Demand Response and Open Automated Demand Response Opportunities for Data Centers. California Energy

413

Adapting to health impacts of climate change: a study of UNFCCC Annex I  

Science Journals Connector (OSTI)

Adapting to the health effects of climate change is one of the key challenges facing public health this century. Our knowledge of progress on adaptation, however, remains in its infancy. Using the Fifth National Communications of Annex I parties to the UNFCCC, 1912 initiatives are systematically identified and analyzed. 80% of the actions identified consist of groundwork (i.e.preparatory) action, with only 20% constituting tangible adaptations. No health vulnerability was recognized by all 38 Annex I countries. Furthermore, while all initiatives affect at least one health vulnerability, only 15% had an explicit human health component. Consideration for the special needs of vulnerable groups is uneven and underdeveloped. Climate change is directly motivating 71% of groundwork actions, and 61% of adaptation initiatives are being mainstreamed into existing institutions or programs. We conclude that the adaptation responses to the health risks of climate change remain piecemeal. Policymakers in the health sector must engage with stakeholders to implement adaptation that considers how climate change will impact the health of each segment of the population, particularly within those groups already considered most vulnerable to poor health outcomes.

A C Lesnikowski; J D Ford; L Berrang-Ford; J A Paterson; M Barrera; S J Heymann

2011-01-01T23:59:59.000Z

414

Dangerous climate change and the importance of adaptation for the Arctic's Inuit  

Science Journals Connector (OSTI)

The Arctic's climate is changing rapidly, to the extent that 'dangerous' climate change as defined by the United Nations Framework on Climate Change might already be occurring. These changes are having implications for the Arctic's Inuit population and are being exacerbated by the dependence of Inuit on biophysical resources for livelihoods and the low socio-economichealth status of many northern communities. Given the nature of current climate change and projections of a rapidly warming Arctic, climate policy assumes a particular importance for Inuit regions. This paper argues that efforts to stabilize and reduce greenhouse gas emissions are urgent if we are to avoid runaway climate change in the Arctic, but unlikely to prevent changes which will be dangerous for Inuit. In this context, a new policy discourse on climate change is required for Arctic regionsone that focuses on adaptation. The paper demonstrates that states with Inuit populations and the international community in general has obligations to assist Inuit to adapt to climate change through international human rights and climate change treaties. However, the adaptation deficit, in terms of what we know and what we need to know to facilitate successful adaptation, is particularly large in an Arctic context and limiting the ability to develop response options. Moreover, adaptation as an option of response to climate change is still marginal in policy negotiations and Inuit political actors have been slow to argue the need for adaptation assistance. A new focus on adaptation in both policy negotiations and scientific research is needed to enhance Inuit resilience and reduce vulnerability in a rapidly changing climate.

James D Ford

2009-01-01T23:59:59.000Z

415

Education and training for radiation emergency medical management in Japan  

Science Journals Connector (OSTI)

Abstract. The radiation emergency medical management are very rarely called upon. The points of our greatest concern on those occasions, are traumatized patients contaminated with radioactive substances. Such patients are in need of emergency medical care, where the medical team is inexperienced in treating cases of radiation contamination. After the criticality accident of a uranium fuel fabrication facility at Tokai-mura in 1999, the medical system for radiation accidents in Japan has thoroughly changed. On request by the Ministry of Education, Culture, Sports, Science and Technology, we have conducted medical education and training on how to treat emergency cases of radiation accidents for the people concerned with emergency medicine, namely medical doctors, nurses, radiation technicians, emergency rescue squads, and health physicists in nuclear power plants. Education and training have been carried out repeatedly at 35 cities and towns for the last 5years. The contents of education and training were lectures, simulation exercises and practical exercises. As a result, more than 80% of medical facilities held responsible for the primary treatment of victims of radiation accidents replied they can handle the cases with skill and knowledge in treating traumatized patients accompanied by radiation contamination without feeling undue stress of radiation. Education and training are continually conducted in cooperation with the experts of radiation emergency medicine such as Nagasaki University.

Tatsuya Kinugasa

2007-01-01T23:59:59.000Z

416

Petascale Adaptive Computational Fluid Dynamics | Argonne Leadership  

NLE Websites -- All DOE Office Websites (Extended Search)

Petascale Adaptive Computational Fluid Dynamics Petascale Adaptive Computational Fluid Dynamics PI Name: Kenneth Jansen PI Email: jansen@rpi.edu Institution: Rensselaer Polytechnic Institute The specific aim of this request for resources is to examine scalability and robustness of our code on BG/P. We have confirmed that, during the flow solve phase, our CFD flow solver does exhibit perfect strong scaling to the full 32k cores on our local machine (CCNI-BG/L at RPI) but this will be our first access to BG/P. We are also eager to study the performance of the adaptive phase of our code. Some aspects have scaled well on BG/L (e.g., refinement has produced adaptive meshes that take a 17 million element mesh and perform local adaptivity on 16k cores to match a requested size field to produce a mesh exceeding 1 billion elements) but other aspects (e.g.,

417

ORISE: Radiation Emergency Training for Iraq, South Africa and Morocco  

NLE Websites -- All DOE Office Websites (Extended Search)

International Training International Training REAC/TS Provides International Radiation Emergency Medical Response Training for Emergency Responders In support of the National Nuclear Security Administration's international approach to nuclear and radiological incident response, REAC/TS staff provide training to physicians, nurses and emergency responders in multiple countries each year. REAC/TS has conducted radiation emergency medical response training in Iraq, Kuwait, Morocco, Singapore, South Africa, and Thailand. "As one of the world's primary responders to nuclear and radiological accidents, it's critical that REAC/TS help prepare a variety of health care professionals for the medical management of radiation accidents," said REAC/TS Medical/Technical Director Dr. Albert Wiley. "Our medical

418

E-Print Network 3.0 - adaptive systems theory Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

systems theory Page: << < 1 2 3 4 5 > >> 1 From Adaptive Hypermedia to the Adaptive Web Systems Summary: 1 From Adaptive Hypermedia to the Adaptive Web Systems Peter...

419

ARM - Measurement - Backscattered radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

govMeasurementsBackscattered radiation govMeasurementsBackscattered radiation ARM Data Discovery Browse Data Comments? We would love to hear from you! Send us a note below or call us at 1-888-ARM-DATA. Send Measurement : Backscattered radiation The scattering of radiant energy into the hemisphere of space bounded by a plane normal to the direction of the incident radiation and lying on the same side as the incident ray. Categories Aerosols, Cloud Properties Instruments The above measurement is considered scientifically relevant for the following instruments. Refer to the datastream (netcdf) file headers of each instrument for a list of all available measurements, including those recorded for diagnostic or quality assurance purposes. ARM Instruments AOS : Aerosol Observing System IAP : In-situ Aerosol Profiles (Cessna Aerosol Flights)

420

Low Dose Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Ancient Salt Beds Ancient Salt Beds Repository Science Renewable Energy The WIPP Underground may be ideal to study effects of Very Low Dose Rates on Biological Systems Low Background Radiation Experiment We're all bathing in it. It's in the food we eat, the water we drink, the soil we tread and even the air we breathe. It's background radiation, it's everywhere and we can't get away from it. But what would happen if you somehow "pulled the plug" on natural background radiation? Would organisms suffer or thrive if they grew up without their constant exposure to background radiation? That's what a consortium of scientists conducting an experiment at the Waste Isolation Pilot Plant aim to find out. Despite being an underground repository for transuranic radioactive waste,

Note: This page contains sample records for the topic "radiation adaptive responses" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


421

Radiation from accelerated branes  

Science Journals Connector (OSTI)

The radiation emitted by accelerated fundamental strings and D-branes is studied within the linear approximation to the supergravity limit of string theory. We show that scalar, gauge field and gravitational radiation is generically emitted by such branes. In the case where an external scalar field accelerates the branes, we derive a Larmor-type formula for the emitted scalar radiation and study the angular distribution of the outgoing energy flux. The classical radii of the branes are calculated by means of the corresponding Thompson scattering cross sections. Within the linear approximation, the interaction of the external scalar field with the velocity fields of the branes gives a contribution to the observed gauge field and gravitational radiation.

Mohab Abou-Zeid and Miguel S. Costa

2000-04-26T23:59:59.000Z

422

Radiation Induced Mammary Cancer  

Science Journals Connector (OSTI)

......Induced Mammary Cancer R.L. Ullrich * R.J. Preston # * Department of Radiation Therapy, University of Texas Medical Branch, Galveston, TX 77550 # Biology Division Oak Ridge National Laboratory Oak Ridge, TN 37831, U.S.A Over the last......

R.L. Ullrich; R.J. Preston

1991-12-01T23:59:59.000Z

423

Flexible Composite Radiation Detector  

NLE Websites -- All DOE Office Websites (Extended Search)

Flexible Composite Radiation Detector Flexible Composite Radiation Detector Flexible Composite Radiation Detector A flexible composite scintillator was prepared by mixing fast, bright, dense rare-earth doped powdered oxyorthosilicate (such as LSO:Ce, LSO:Sm, and GSO:Ce) scintillator with a polymer binder. Available for thumbnail of Feynman Center (505) 665-9090 Email Flexible Composite Radiation Detector A flexible composite scintillator was prepared by mixing fast, bright, dense rare-earth doped powdered oxyorthosilicate (such as LSO:Ce, LSO:Sm, and GSO:Ce) scintillator with a polymer binder. The binder is transparent to the scintillator emission. The composite is seamless and can be made large and in a wide variety of shapes. Importantly, the composite can be tailored to emit light in a spectral region that matches the optimum

424

Radiation Safety Training Basic Radiation Safety Training for  

E-Print Network (OSTI)

Radiation Safety Training Basic Radiation Safety Training for Sealed Source Users for Physics 461 & 462 Modern Physics Laboratory Spring 2007 #12;Radiation Safety Department, University of Tennessee Purpose: To provide basic radiation safety training to the users of sealed sources located

Dai, Pengcheng

425

Radiation Safety Training Basic Radiation Safety Training for  

E-Print Network (OSTI)

Radiation Safety Training Basic Radiation Safety Training for X-ray Users for Physics 461 & 462 Modern Physics Laboratory Spring 2007 #12;#12;Radiation Safety Department, University of Tennessee Protocol Title: Basic Radiation Safety Training for X-ray Users Drafted By: Chris Millsaps, RSS Reviewers

Dai, Pengcheng

426

Low Dose Radiation Research Program: Genetic Factors Affecting  

NLE Websites -- All DOE Office Websites (Extended Search)

Genetic Factors Affecting Susceptibility to Low-Doses of Ionizing Genetic Factors Affecting Susceptibility to Low-Doses of Ionizing Radiation. Authors: William F. Morgan, Pat Concannon & John H.J. Petrini The goal of this program is to test the hypothesis that mice heterozygous for the NBS1 gene are genetically susceptible to low doses of ionizing radiation. Patients with Nijmegen Breakage Syndrome (NBS) are radiation sensitive, because of defects in cellular responses to radiation induced genetic damage. It is unclear whether humans heterozygous for the mutations associated with NBS are radiation sensitive and results from cell culture experiments give conflicting results. In collaboration with John Petrini at the Memorial Sloan Kettering Cancer Center in New York City we developed a mouse model of this disorder and are directly testing the hypothesis

427

Low dose radiation combines with the Src oncoprotein to transform  

NLE Websites -- All DOE Office Websites (Extended Search)

radiation combines with the Src oncoprotein to transform radiation combines with the Src oncoprotein to transform pre-malignant human breast cells Paul Yaswen Lawrence Berkeley National Laboratory Abstract Goal: Determine whether low dose radiation exerts persistent epigenetic effects that promote malignancy. Background and Significance: Some persistent carcinogenic effects of radiation may not be traceable to specific DNA sequence alterations and may not be linearly related to dose. Through the biochemical initiation of positive feedback loops, ionization-induced events may have heritable non-linear effects on cellular behavior. Inflammatory responses involving the transcription factor NFκB may be subject to such effects. Increased NFκB activity has been strongly linked to carcinogenesis in a number of published in vitro and in vivo studies (reviewed in [1]). Since radiation

428

Adapting agriculture to climate change  

Science Journals Connector (OSTI)

...foster governance and political rights, among many others...broad resilience to risk or to promote sustainable...habitat loss, less risk of carbon loss...services, including insurance (55). Importantly...assessing climate risk and devising response...underlying socioeconomic, political, and technological...

S. Mark Howden; Jean-Franois Soussana; Francesco N. Tubiello; Netra Chhetri; Michael Dunlop; Holger Meinke

2007-01-01T23:59:59.000Z

429

Radiative Muon Capture  

Science Journals Connector (OSTI)

The theory of radiative muon capture is developed. The discussion includes both parity conserving and nonconserving effects. The Gell-Mann weak magnetic term and the induced pseudoscalar are included, along with comparable relativistic effects in the nucleons. The theory is applied to light nuclei and especially to the radiative Godfrey reaction ?-+C126??+?+B125. An experiment to detect the induced pseudoscalar directly is proposed.

Jeremy Bernstein

1959-08-01T23:59:59.000Z

430

Low Dose Radiation Program: Links - Agencies with Radiation Regulatory  

NLE Websites -- All DOE Office Websites (Extended Search)

Agencies with Radiation Regulatory Concerns and Involvement Agencies with Radiation Regulatory Concerns and Involvement Biological Effects of Low Level Exposures (BELLE) Canadian Nuclear Safety Commission Center for Risk Excellence Health Protection Agency The Health Risks of Extraterrestrial Environments International Commission on Radiation Units and Measurements, Inc. International Commission on Radiological Protection (ICRP) International Radiation Protection Association (IRPA) NASA Space Radiation Program National Academy of Sciences (NAS) Nuclear and Radiation Studies Board National Aeronautics and Space Administration (NASA) NASA OBRR Task Book Publication National Council on Radiation Protection (NCRP) National Institute of Environmental Health Sciences (NIEHS) National Toxicology Program (NTP) Occupational Safety and Health Administration (OSHA)

431

Radiative muon capture  

Science Journals Connector (OSTI)

It is shown by relating the transition amplitude of radiative muon capture to that of radiative pion capture, that the transition amplitude of radiative muon capture proposed recently by Hwang and Primakoff differs from the others mainly by Low's counter terms. Despite the fact that the "original" transition amplitude does not violate seriously the conservation of the hadronic electromagnetic current, Low's counter terms, as introduced via Low's prescription to secure the presence of small conservation-of-hadronic-electromagnetic-current-breaking terms, are confirmed to be of numerical importance. Further, it is found in the "elementary-particle" treatment of radiative muon capture that the uncertainty arising from the nuclear structure can be reduced to become negligible. Therefore, an exclusive radiative muon capture experiment can in principle differentiate the Hwang-Primakoff theory from the others and yet provide a comprehensive test of partial conservation of axial-vector current.RADIOACTIVITY Theories of radiative muon capture, linearity hypothesis versus Low's prescription; nuclear structure and PCAC.

W -Y. P. Hwang

1980-07-01T23:59:59.000Z

432

CONSULTATION RESPONSE Wellcome Trust response to Workforce  

E-Print Network (OSTI)

account of in workforce planning. The importance of integrating academic training with clinical trainingCONSULTATION RESPONSE Wellcome Trust response to Workforce of the Healthcare Science Workforce Modernising Scientific Careers: The Next Steps Response by the Wellcome Trust

Rambaut, Andrew

433

IAEACN69/EXP2/12 Highly Radiative Plasmas for Local Transport Studies and Power and Particle  

E-Print Network (OSTI)

tool for local transport studies, because the distribution of power loss between radiation. The response of the electron and ion temperatures to greatly increased radiative losses from the electrons alpha heating power must be dispersed. [1] Heat removal by radiation from controlled injection

434

IAEA-CN-69/EXP2/12 Highly Radiative Plasmas for Local Transport Studies and Power and Particle  

E-Print Network (OSTI)

for local transport studies, because the distribution of power loss between radiation and conduction plus. The response of the electron and ion temperatures to greatly increased radiative losses from the electrons alpha heating power must be dispersed.?[1] Heat removal by radiation from controlled injection

435

Radiation damage to scintillator in the D0 luminosity monitor  

SciTech Connect

We report the result of evaluating radiation damage to Bicron BC408 plastic scintillator used in the D0 Luminosity Monitor during Run IIa. The Luminosity Monitor provides pseudo-rapidity coverage over the range 2.7 < |{eta}| < 4.4, with the radiation dose in Run IIa estimated to be 0.5 MRad for the region closest to the beams. We find the light yield is degraded by 10-15% due to radiation damage by comparing new and old scintillator in four observables: (1) visual inspection, (2) optical transmittance, (3) response to the radioactive source of {sup 90}Sr and (4) light yield for cosmic rays.

Casey, Brendan; DeVaughan, Kayle; /Brown U. /Nebraska U.; Enari, Yuji; Partridge, Richard; /Brown U.; Yacoob, Sahal; /Northwestern U.

2006-12-01T23:59:59.000Z

436

Demand response enabling technology development  

E-Print Network (OSTI)

global and diffuse solar radiation sensors, wind directionfrom a crude radiation sensor. Solar Radiation Conductiosensor data (Temperature, motion, relative humidity, solar

Arens, Edward; Auslander, David; Huizenga, Charlie

2008-01-01T23:59:59.000Z

437

Pacific Adaptation Strategy Assistance Program Dynamical Seasonal Forecasting  

E-Print Network (OSTI)

Pacific Adaptation Strategy Assistance Program Dynamical Seasonal Forecasting Seasonal Prediction · POAMA · Issues for future Outline #12;Pacific Adaptation Strategy Assistance Program Major source Adaptation Strategy Assistance Program El Nino Mean State · Easterlies westward surface current upwelling

Lim, Eun-pa

438

2014 DOE Climate Change Adaptation Plan | Department of Energy  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

2014 DOE Climate Change Adaptation Plan 2014 DOE Climate Change Adaptation Plan Document presents the U.S. Department of Energy (DOE) 2014 plan for adapting to climate change....

439

Radiation Response of Strained Silicon-Germanium Superlattices  

E-Print Network (OSTI)

17 [22]. : : : : : : : : : : : : : : 30 19 Reduction in measured kink angle due to equilibration of analyz- ing beam caused by beam focusing in the channeling axis [22]. : : : : 30 20 Two dimensional backscattering yield map of h110i axis in (100... orders of magnitude because of the steering e ect of the rows of atoms. Alignment of the ion beam with a crystal plane will also cause a reduction of backscattering yield, though this reduction will be less than in the case of axial channeling. When...

Martin, Michael Scott

2011-08-08T23:59:59.000Z

440

Total dose radiation response of plasma-damaged NMOS devices  

SciTech Connect

Plasma-damaged NMOS devices were subjected to the X-ray total dose irradiation. Unlike the traditional hot-carrier or Fowler-Nordheim (F-N) stress where the hole trap generation is less pronounced, this study shows enhanced hole trap and interface trap generation on plasma-damaged devices after total dose irradiation.

Yue, J.; Lo, E.; Flanery, M. [Honeywell Solid-State Electronic Center, Plymouth, MN (United States)] [Honeywell Solid-State Electronic Center, Plymouth, MN (United States)

1997-11-01T23:59:59.000Z

Note: This page contains sample records for the topic "radiation adaptive responses" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


441

REPORT NO. 8 radiation hazards  

E-Print Network (OSTI)

REPORT NO. 8 REVISED guidance for the control of radiation hazards in uranium mining SEPTEMBER 1967 OF RADIATION HAZARDS IN URANIUM MINING SEPTEMBER 1967 Staff Report of the FEDERAL RADIATION COUNCIL #12;FEDERAL...... .... .._ _.... Section I. Introduction. . . Section II. The Radiation Environment AssociatedWith Uranium Mining. Section

442

Appendix G: Radiation HYDROGEN ATOM  

E-Print Network (OSTI)

. People are exposed to naturally occurring radiation constantly. For example, cosmic radiation; radon effects on the environment and biological systems. Radiation comes from natural and human-made sourcesAppendix G: Radiation #12;#12;P P P E E E N NN HYDROGEN ATOM DEUTERIUM ATOM TRITIUM ATOM HYDROGEN

Pennycook, Steve

443

Appendix A: Radiation HYDROGEN ATOM  

E-Print Network (OSTI)

. People are exposed to naturally occurring radiation constantly. For example, cosmic radiation; radon effects on the environment and biological systems. Radiation comes from natural and human-made sourcesAppendix A: Radiation #12;P P P E E E N NN HYDROGEN ATOM DEUTERIUM ATOM TRITIUM ATOM HYDROGEN

Pennycook, Steve

444

Mechanisms underlying cellular responses of cells from haemopoeitic tissue  

NLE Websites -- All DOE Office Websites (Extended Search)

underlying cellular responses of cells from haemopoeitic tissue underlying cellular responses of cells from haemopoeitic tissue to low dose-low LET radiation Munira Kadhim Oxford Brookes University Abstract Radiation-induced responses at the cellular and whole body levels are influenced by genetic predisposition, with implications for environmental and potentially, diagnostic exposures. Currently, the extent to which genetic background play a role in the mechanisms and signalling pathways involved in radiation-induced delayed Genomic Instability (GI) is not fully understood. In previous studies, our results have shown that the CBA/H and C57BL/6 mouse strains, have differing sensitivities in the induction of radiation-induced genomic instability (RIGI) in terms of chromosomal instability, following exposure to high dose-high LET and high dose-low LET

445

Proteasome Structures Affected by Ionizing Radiation  

Science Journals Connector (OSTI)

...Effect of ionizing radiation on 26S but...radiation doses, and immediately...the dose range 1 to 20 Gy...ionizing radiation induced a...38), ionizing radiation (39...over a wide range of radiation doses and further...

Milena Pervan; Keisuke S. Iwamoto; and William H. McBride

2005-07-01T23:59:59.000Z

446

Commercial & Industrial Demand Response  

NLE Websites -- All DOE Office Websites (Extended Search)

Resources News & Events Expand News & Events Skip navigation links Smart Grid Demand Response Agricultural Residential Demand Response Commercial & Industrial Demand Response...

447

National Adaptation Forum Webinar Series: Out of Town, Not Out...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

Adaptation Forum Webinar Series: Out of Town, Not Out of Trouble: Small Agriculture and Indigenous Communities National Adaptation Forum Webinar Series: Out of Town, Not Out of...

448

Burundi-National Adaptation Plan of Action to Climate Change...  

Open Energy Info (EERE)

Burundi-National Adaptation Plan of Action to Climate Change Jump to: navigation, search Name Burundi-National Adaptation Plan of Action to Climate Change AgencyCompany...

449

GIZ Sourcebook Module 5f: Adapting Urban Transport to Climate...  

Open Energy Info (EERE)

f: Adapting Urban Transport to Climate Change Jump to: navigation, search Tool Summary LAUNCH TOOL Name: GIZ Sourcebook Module 5f: Adapting Urban Transport to Climate Change...

450

Rwanda-National Adaptation Programs of Action to Climate Change...  

Open Energy Info (EERE)

Name Rwanda-National Adaptation Programs of Action to Climate Change AgencyCompany Organization United Nations Environment Programme Topics Adaptation, Background analysis...

451

Software Adaptation Patterns for Service-Oriented Architectures .  

E-Print Network (OSTI)

??This thesis describes the concept of software adaptation patterns and how they can be used in software adaptation of service-oriented architectures. The patterns are described (more)

Hashimoto, Koji

2010-01-01T23:59:59.000Z

452

Adapting technology to keep the national infrastructure safe...  

NLE Websites -- All DOE Office Websites (Extended Search)

Adapting technology to keep the national infrastructure safe and secure Identifying threats and responding to disasters September 1, 2013 Adapting Lab technology to help recover...

453

Development of an adaptive fuzzy logic controller for HVAC system.  

E-Print Network (OSTI)

??An adaptive approach to control a cooling coil chilled water valve operation, called adaptive fuzzy logic control (AFLC), is developed and validated in this study. (more)

Navale, Rahul Laxman

2006-01-01T23:59:59.000Z

454

Adaptive Rejection of Narrow Band Disturbance in Hard Disk Drives  

E-Print Network (OSTI)

feedback representation of the PAA for adapting narrow bandrepresentation of the PAA for stability analysis. .92adaptation algorithm (PAA). These identified parameters are

Zheng, Qixing

2009-01-01T23:59:59.000Z

455

Dose-Response Relations from Epidemiological Studies [and Discussion  

Science Journals Connector (OSTI)

...research-article Dose-Response Relations...The paper discusses dose-response relations...available over a range wide enough to make...chrysotile asbestos and ionizing radiation. In both cases the...increases with the dose of asbestos (principally...

1981-01-01T23:59:59.000Z

456

Radiation delivery system and method  

DOE Patents (OSTI)

A radiation delivery system and method are described. The system includes a treatment configuration such as a stent, balloon catheter, wire, ribbon, or the like, a portion of which is covered with a gold layer. Chemisorbed to the gold layer is a radiation-emitting self-assembled monolayer or a radiation-emitting polymer. The radiation delivery system is compatible with medical catheter-based technologies to provide a therapeutic dose of radiation to a lesion following an angioplasty procedure.

Sorensen, Scott A. (Overland Park, KS); Robison, Thomas W. (Los Alamos, NM); Taylor, Craig M. V. (Jemez Springs, NM)

2002-01-01T23:59:59.000Z

457

Low Dose Radiation Research Program: Low Dose Ionizing Radiation-Induced  

NLE Websites -- All DOE Office Websites (Extended Search)

Low Dose Ionizing Radiation-Induced Effects in Irradiated and Low Dose Ionizing Radiation-Induced Effects in Irradiated and Unirradiated cells: Pathways Analysis in Support of Risk Assessment. Authors: B.E. Lehnert, R. Cary, D. Gadbois, and G. Gupta. Institutions: Bioscience Division, Los Alamos National Laboratory. The scientific literature presents a confusing picture concerning health risks due to low dose ionizing radiation (LDIR), e.g., <1-10 cGy. Some effects of LDIR such as enhanced rates of cell proliferation and the induction of radioadaptation may be benign under some circumstances. Other evidence suggests LDIR can be hazardous and that a threshold for potentially detrimental responses, e.g., increases in intracellular reactive oxygen species (ROS), increases in sister chromatid exchanges (SCE), alterations in gene or protein expression profiles, and increased

458

Reducing Radiation Damage  

SciTech Connect

This talk describes the use of a modified treatment sequence, i.e., radiation dose, geometry, dwell time, etc., to mitigate some of the deleterious effects of cancer radiotherapy by utilizing natural cell repair processes. If bad side effects can be reduced, a more aggressive therapy can be put into place. Cells contain many mechanisms that repair damage of various types. If the damage can not be repaired, cells will undergo apoptosis (cell death). Data will be reviewed that support the fact that a small dose of radiation will activate damage repair genes within a cell. Once the mechanisms are fully active, they will efficiently repair the severe damage from a much larger radiation dose. The data ranges from experiments on specific cell cultures using microarray (gene chip) techniques to experiments on complete organisms. The suggested effect and treatment is consistent with the assumption that all radiation is harmful, no matter how small the dose. Nevertheless, the harm can be reduced. These mechanisms need to be further studied and characterized. In particular, their time dependence needs to be understood before the proposed treatment can be optimized. Under certain situations it is also possible that the deleterious effects of chemotherapy can be mitigated and the damage to radiation workers can be reduced.

Blankenbecler, Richard

2006-06-05T23:59:59.000Z

459

American Society for Radiation Oncology (ASTRO) 2012 Workforce Study: The Radiation Oncologists' and Residents' Perspectives  

SciTech Connect

Purpose: The American Society for Radiation Oncology (ASTRO) conducted the 2012 Radiation Oncology Workforce Survey to obtain an up-to-date picture of the workforce, assess its needs and concerns, and identify quality and safety improvement opportunities. The results pertaining to radiation oncologists (ROs) and residents (RORs) are presented here. Methods: The ASTRO Workforce Subcommittee, in collaboration with allied radiation oncology professional societies, conducted a survey study in early 2012. An online survey questionnaire was sent to all segments of the radiation oncology workforce. Respondents who were actively working were included in the analysis. This manuscript describes the data for ROs and RORs. Results: A total of 3618 ROs and 568 RORs were surveyed. The response rate for both groups was 29%, with 1047 RO and 165 ROR responses. Among ROs, the 2 most common racial groups were white (80%) and Asian (15%), and the male-to-female ratio was 2.85 (74% male). The median age of ROs was 51. ROs averaged 253.4 new patient consults in a year and 22.9 on-treatment patients. More than 86% of ROs reported being satisfied or very satisfied overall with their career. Close to half of ROs reported having burnout feelings. There was a trend toward more frequent burnout feelings with increasing numbers of new patient consults. ROs' top concerns were related to documentation, reimbursement, and patients' health insurance coverage. Ninety-five percent of ROs felt confident when implementing new technology. Fifty-one percent of ROs thought that the supply of ROs was balanced with demand, and 33% perceived an oversupply. Conclusions: This study provides a current snapshot of the 2012 radiation oncology physician workforce. There was a predominance of whites and men. Job satisfaction level was high. However a substantial fraction of ROs reported burnout feelings. Perceptions about supply and demand balance were mixed. ROs top concerns reflect areas of attention for the healthcare sector as a whole.

Pohar, Surjeet, E-mail: spohar@iuhealth.org [Indiana University Health East, Indianapolis, Indiana (United States); Fung, Claire Y. [Commonwealth Newburyport Cancer Center, Newburyport, Massachusetts (United States); Hopkins, Shane [William R. Bliss Cancer Center, Ames, Iowa (United States); Miller, Robert [Mayo Clinic, Rochester, Minnesota (United States); Azawi, Samar [VA Veteran Hospital/University of California Irvine, Newport Beach, California (United States); Arnone, Anna; Patton, Caroline [ASTRO, Fairfax, Virginia (United States); Olsen, Christine [Massachusetts General Hospital, Boston, Massachusetts (United States)

2013-12-01T23:59:59.000Z

460

Fluctuations and information filtering in coupled populations of spiking neurons with adaptation  

Science Journals Connector (OSTI)

Finite-sized populations of spiking elements are fundamental to brain function but also are used in many areas of physics. Here we present a theory of the dynamics of finite-sized populations of spiking units, based on a quasirenewal description of neurons with adaptation. We derive an integral equation with colored noise that governs the stochastic dynamics of the population activity in response to time-dependent stimulation and calculate the spectral density in the asynchronous state. We show that systems of coupled populations with adaptation can generate a frequency band in which sensory information is preferentially encoded. The theory is applicable to fully as well as randomly connected networks and to leaky integrate-and-fire as well as to generalized spiking neurons with adaptation on multiple time scales.

Moritz Deger; Tilo Schwalger; Richard Naud; Wulfram Gerstner

2014-12-01T23:59:59.000Z

Note: This page contains sample records for the topic "radiation adaptive responses" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


461

Information Resources: Adaptive Street Lighting Controls  

NLE Websites -- All DOE Office Websites (Extended Search)

Adaptive Street Lighting Controls Adaptive Street Lighting Controls This two-part DOE Municipal Solid-State Street Lighting Consortium webinar focused on LED street lighting equipped with adaptive control components. In Part I, presenters Amy Olay of the City of San Jose, CA, and Kelly Cunningham of the California Lighting Technology Center at UC Davis discussed their experiences as early adopters of these smart street lighting systems. In Part II, presenters Laura Stuchinsky of the City of San Jose, CA, and Michael Poplawski of Pacific Northwest National Laboratory explored the MSSLC's recently released Model Specification for Adaptive Control and Remote Monitoring of LED Roadway Luminaires. Part I: Experiences and Benefits June 11, 2013 View the presentation slides Part II: Reviewing the MSSLC's Model Specification

462

Human adaptation of avian influenza viruses  

E-Print Network (OSTI)

Human adaptation of avian influenza viruses pose an enormous public health challenge as the human population is predominantly naive to avian influenza antigens. As such, constant surveillance is needed to monitor the ...

Srinivasan, Karunya

2012-01-01T23:59:59.000Z

463

Marginalized Monitoring: Adaptively Managing Urban Stormwater  

E-Print Network (OSTI)

environmental assessment, 28 Superfund decisionmaking, 29 Endangered Species Act decisionmaking, 30 and water management.Environmental Impacts Under Florida Water Law: From Water Wars Towards Adaptive Management ,water infrastructure problems. And yet, the environmental management

Scanlan, Melissa K; Tai, Stephanie

2013-01-01T23:59:59.000Z

464

A Logical Characterization of Adaptive Educational Hypermedia  

E-Print Network (OSTI)

reference models for adaptive hypermedia, e.g. the AHAM Reference Model [4], or the Munich Reference Model [20]. Both, the AHAM and Munich Reference Model, extend the Dexter Hypertext Model [16], and pro- vide

Henze, Nicola

465

Adaptive Resource Management Craig E. Wills  

E-Print Network (OSTI)

Adaptive Resource Management Craig E. Wills Surendar Chandra # Computer Science Department fixed approaches to manage information. However fixed solutions to information management. These servers manage information about machines, users, files and other objects. The typical approach

Chandra, Surendar

466

Optimization Online - Multistage Adaptive Robust Optimization for ...  

E-Print Network (OSTI)

Sep 5, 2014 ... ... with the increasing penetration of wind and solar power generation has ... Keywords: Electric energy systems, multistage robust optimization, ... Multistage Adaptive Robust Optimization for the Unit Commitment Problem.

Alvaro Lorca

2014-09-05T23:59:59.000Z

467

Anisotropic Grid Adaptation for Multiple Aerodynamic Outputs  

E-Print Network (OSTI)

Anisotropic gridadaptive strategies are presented for viscous flow simulations in which the accurate prediction of multiple aerodynamic outputs (such as the lift, drag, and moment coefficients) is required from a single ...

Venditti, David A.

468

Statistical Design for Adaptive Weather Observations  

Science Journals Connector (OSTI)

Suppose that one has the freedom to adapt the observational network by choosing the times and locations of observations. Which choices would yield the best analysis of the atmospheric state or the best subsequent forecast? Here, this problem of ...

L. Mark Berliner; Zhan-Qian Lu; Chris Snyder

1999-08-01T23:59:59.000Z

469

Adaptive unstructured volume remeshing - I: the method  

Science Journals Connector (OSTI)

We present an adaptive remeshing algorithm for meshes of unstructured triangles in two dimensions and unstructured tetrahedra in three dimensions. The algorithm automatically adjusts the size of the elements with time and position in the computational ...

Anthony Anderson; Xiaoming Zheng; Vittorio Cristini

2005-09-01T23:59:59.000Z

470

Low Dose Radiation Program: Links - Organizations Conducting Radiation  

NLE Websites -- All DOE Office Websites (Extended Search)

Conducting Low Dose Radiation Research Conducting Low Dose Radiation Research DOE Low Dose Radiation Research Program DoReMi Integrating Low Dose Research High Level Expert Group (HLEG) on European Low Dose Risk Research Multidisciplinary European Low Dose Initiative (MELODI) RISC-RAD Radiosensitivity of Individuals and Susceptibility to Cancer induced by Ionizing Radiation United States Transuranium & Uranium Registries Organizations Conducting other Radiation Research Argonne National Laboratory (ANL) Armed Forces Radiology Research Institute (AFRRI) Atmospheric Radiation Measurement (ARM) Program Brookhaven National Laboratory (BNL) Center for Devices and Radiological Health (CDRH) Central Research Institute of Electric Power Industry (CRIEPI) Colorado State University Columbia University

471

ORISE: Helping Strengthen Emergency Response Capabilities for DOE  

NLE Websites -- All DOE Office Websites (Extended Search)

Response Response Firefighters assisting a disaster victim The Oak Ridge Institute for Science and Education (ORISE) helps strengthen government agencies' emergency response capabilities through a variety of exercises, from tabletop training to full-scale drills. ORISE supports emergency response needs across multiple disciplines, including the medical management of radiation incidents through the U.S. Department of Energy's (DOE) Radiation Emergency Assistance Center/Training Site (REAC/TS). As a DOE reponse asset, REAC/TS is available 24 hours a day/seven days a week to deploy and provide emergency medical treatment for all types of radiation exposure anywhere in the world. Each interdisciplinary team includes a physician, nurse/paramedic and health physicist who are

472

Semiconductor radiation detector  

DOE Patents (OSTI)

A semiconductor detector for ionizing electromagnetic radiation, neutrons, and energetic charged particles. The detecting element is comprised of a compound having the composition I-III-VI.sub.2 or II-IV-V.sub.2 where the "I" component is from column 1A or 1B of the periodic table, the "II" component is from column 2B, the "III" component is from column 3A, the "IV" component is from column 4A, the "V" component is from column 5A, and the "VI" component is from column 6A. The detecting element detects ionizing radiation by generating a signal proportional to the energy deposited in the element, and detects neutrons by virtue of the ionizing radiation emitted by one or more of the constituent materials subsequent to capture. The detector may contain more than one neutron-sensitive component.

Bell, Zane W. (Oak Ridge, TN); Burger, Arnold (Knoxville, TN)

2010-03-30T23:59:59.000Z

473

Radiation Minimum Temperatures  

Science Journals Connector (OSTI)

Frost resulting from cooling of vegetation by nocturnal radiation is a serious agricultural problem. Because of the number of variables involved attacks on this problem from a purely theoretical point of view have met with only moderate success. It seems logical to suppose that an instrument might be devised which would speed up the natural radiation processes and enable an observer to obtain in a few hours a measure of the cooling which occurs naturally over a period of 12 to 14 hr. Such an instrument could serve as a frost warning device. This paper describes the construction of a radiation device and presents experimental evidence to show that it can be used as a predictor of freezing temperatures at vegetation level.

Francis K. Davis Jr.

1957-01-01T23:59:59.000Z

474

Audible radiation monitor  

SciTech Connect

This invention consists of a method and apparatus for monitoring ionizing radiation comprising radiation detectors in electrical connection with an isotopic analyzer and a device for producing chords to which each isotope is mapped so that the device produces a unique chord for each isotope. Preferably the chords are pleasing to the ear, except for chords representing unexpected isotopes, and are louder or softer depending on the level of radioactivity produced by each isotope, and musical instrument voices may be simulated in producing the chords as an aid to distinguishing similar-sounding chords. Because of the representation by chords, information regarding the level and composition of the radiation in an area can be conveyed to workers in that area more effectively and yet without distracting them.

Odell, D.M.C.

1992-12-31T23:59:59.000Z

475

Composition for radiation shielding  

DOE Patents (OSTI)

A composition for use as a radiation shield is disclosed. The shield has a depleted uranium core for absorbing gamma rays and a bismuth coating for preventing chemical corrosion and absorbing gamma rays. Alternatively, a sheet of gadolinium may be positioned between the uranium core and the bismuth coating for absorbing neutrons. The composition is preferably in the form of a container for storing materials that emit radiation such as gamma rays and neutrons. The container is preferably formed by casting bismuth around a pre-formed uranium container having a gadolinium sheeting, and allowing the bismuth to cool. The resulting container is a structurally sound, corrosion-resistant, radiation-absorbing container. 2 figs.

Kronberg, J.W.

1994-08-02T23:59:59.000Z

476

Modulating radiation induced TGFβ and ATM signaling in the DNA damage  

NLE Websites -- All DOE Office Websites (Extended Search)

Modulating radiation induced TGFβ and ATM signaling in the DNA damage Modulating radiation induced TGFβ and ATM signaling in the DNA damage response Jennifer A. Anderson Gray Institute for Radiation Oncology and Biology Abstract Both the ATM and TGFβ signal transduction pathways are essential for cellular and tissue control responses to ionizing radiation and aberrant modifications to these pathways are extensive in cancer. We hypothesize that the ATM and TGFβ signaling pathways are fully induced at high doses of acute low-LET radiation, whereas only partially induced at low doses. Numerous studies have linked the p38 MAPK signaling pathway with the ATM DNA damage response, and others have shown that TGFβ stimulation results in the phosphorylation of p38 MAPK. Our aim is to perturb potential crosstalk between ATM, TGFβ and p38 MAPK at the DNA damage level and

477

Content adaptivity in wireless web access  

Science Journals Connector (OSTI)

While the demand for wireless access to web-based systems increases, it becomes apparent that the design of most systems does not support the use of small screen end-devices such as PDAs or mobile phones. However, enabling wireless access should ... Keywords: adaptivity, cohesion preorder, conceptual modelling, content adaptation, internet, media types, mobile clients, mobile communications, proximity values, web-based systems, wireless access

Klaus-Dieter Schewe; Kinshuk; Tiong Goh

2004-09-01T23:59:59.000Z

478

Fully Adaptive AMG Scott MacLachlan  

E-Print Network (OSTI)

" Ah "-1 ik ff Energy measure: Let G (i) j = (Ah )-1 ij , Sij = G(i) - G (i) j e(j) Ah G(i) Ah Fully, Sij? Apply (localized) relaxation to Ah G(i) = e(i) Fully Adaptive AMG ­ p.11 #12;Approximating Sij to Ah G(i) = e(i) Weighted Jacobi, 1 step: Fully Adaptive AMG ­ p.11 #12;Approximating Sij Can

MacLachlan, Scott

479

Adaptation semantique de documents multimedia Sebastien Laborie  

E-Print Network (OSTI)

Adaptation s´emantique de documents multim´edia S´ebastien Laborie Soutenance de th`ese - 28 Mai 2008 1 S´ebastien Laborie Adaptation s´emantique de documents multim´edia #12;Introduction Probl´ematique Un document multim´edia Constitu´e d'objets multim´edia Texte Image Son Vid´eo Assembl´e par un

Joseph Fourier Grenoble-I, Université

480

ORISE Radiation Emergency Assistance Center/Training Site (REAC/TS):  

NLE Websites -- All DOE Office Websites (Extended Search)

Capabilities Capabilities REAC/TS offers medical management of radiation incidents, consultation and training in radiation emergency medicine REAC/TS staff member providing medical assistance Recognized around the world for its expertise in the medical management of radiation incidents, the Radiation Emergency Assistance Center/Training Site (REAC/TS) at the Oak Ridge Institute for Science and Education (ORISE) provides radiation incident response, consultation and preparedness training, and participates in simulation exercises to address the medical aspects of human exposure to ionizing radiation. As REAC/TS continues to establish international partnerships through education, exercises and conferences, the group is strengthening radiological emergency preparedness and response around the globe. REAC/TS

Note: This page contains sample records for the topic "radiation adaptive responses" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


481

Tunable terahertz radiation source  

SciTech Connect

Terahertz radiation source and method of producing terahertz radiation, said source comprising a junction stack, said junction stack comprising a crystalline material comprising a plurality of self-synchronized intrinsic Josephson junctions; an electrically conductive material in contact with two opposing sides of said crystalline material; and a substrate layer disposed upon at least a portion of both the crystalline material and the electrically-conductive material, wherein the crystalline material has a c-axis which is parallel to the substrate layer, and wherein the source emits at least 1 mW of power.

Boulaevskii, Lev; Feldmann, David M; Jia, Quanxi; Koshelev, Alexei; Moody, Nathan A

2014-01-21T23:59:59.000Z

482

Neutron Energy Response and Background of Electrochemically Etched Nuclear Track Detectors: Study of Various CR-39 Materials  

Science Journals Connector (OSTI)

......Radiation Protection Dosimetry Article Neutron Energy Response and Background of Electrochemically Etched Nuclear Track Detectors: Study of Various CR-39...experiments. Results are presented for the energy dependence of the response of the various......

M. Luszik-Bhadra; W.G. Alberts; E. Piesch

1990-08-01T23:59:59.000Z

483

Integration of video and radiation analysis data  

SciTech Connect

For the past several years, the integration of containment and surveillance (C/S) with nondestructive assay (NDA) sensors for monitoring the movement of nuclear material has focused on the hardware and communications protocols in the transmission network. Little progress has been made in methods to utilize the combined C/S and NDA data for safeguards and to reduce the inspector time spent in nuclear facilities. One of the fundamental problems in the integration of the combined data is that the two methods operate in different dimensions. The C/S video data is spatial in nature; whereas, the NDA sensors provide radiation levels versus time data. The authors have introduced a new method to integrate spatial (digital video) with time (radiation monitoring) information. This technology is based on pattern recognition by neural networks, provides significant capability to analyze complex data, and has the ability to learn and adapt to changing situations. This technique has the potential of significantly reducing the frequency of inspection visits to key facilities without a loss of safeguards effectiveness.

Menlove, H.O.; Howell, J.A.; Rodriguez, C.A.; Eccleston, G.W.; Beddingfield, D.; Smith, J.E. [Los Alamos National Lab., NM (United States); Baumgart, C.W. [EG and G Energy Measurements, Inc., Los Alamos, NM (United States)

1995-12-31T23:59:59.000Z

484

Adaptation to water scarcity in glacier-dependent towns of the Indian Himalayas : impacts, adaptive responses, barriers, and solutions  

E-Print Network (OSTI)

Among the existing and projected impacts of climate change, impacts on water resources are expected to exacerbate the current and future threat of global water scarcity. Glacier-dependent societies are especially vulnerable ...

Sudhalkar, Amruta Anand

2010-01-01T23:59:59.000Z

485

Radiation Effects in the Space Telecommunications Environment  

SciTech Connect

Trapped protons and electrons in the Earth's radiation belts and cosmic rays present significant challenges for electronics that must operate reliably in the natural space environment. Single event effects (SEE) can lead to sudden device or system failure, and total dose effects can reduce the lifetime of a telecommmiications system with significant space assets. One of the greatest sources of uncertainty in developing radiation requirements for a space system is accounting for the small but finite probability that the system will be exposed to a massive solar particle event. Once specifications are decided, standard laboratory tests are available to predict the total dose response of MOS and bipolar components in space, but SEE testing of components can be more challenging. Prospects are discussed for device modeling and for the use of standard commercial electronics in space.

Fleetwood, Daniel M.; Winokur, Peter S.

1999-05-17T23:59:59.000Z

486

Temperature measurements using multicolor pyrometry in thermal radiation heating environments  

SciTech Connect

Temperature measurements are important for thermal-structural experiments in the thermal radiation heating environments such as used for thermal-structural stress analyses. This paper describes the use of multicolor pyrometry for the measurements of diffuse surfaces in thermal radiation environments that eliminates the effects of background radiation reflections and unknown emissivities based on a least-squares algorithm. The near-infrared multicolor pyrometer had a spectral range of 11002400 nm, spectrum resolution of 6 nm, maximum sampling frequency of 2 kHz, working distance of 0.6 m to infinity, temperature range of 7001700 K. The pyrometer wavelength response, nonlinear intensity response, and spectral response were all calibrated. The temperature of a graphite sample irradiated by quartz lamps was then measured during heating and cooling using the least-squares algorithm based on the calibrated irradiation data. The experiments show that higher temperatures and longer wavelengths are more suitable for the thermal measurements in the quartz lamp radiation heating system. This analysis provides a valuable method for temperature measurements of diffuse surfaces in thermal radiation environments.

Fu, Tairan, E-mail: trfu@mail.tsinghua.edu.cn [Key Laboratory for Thermal Science and Power Engineering of Ministry of Education, Department of Thermal Engineering, Tsinghua University, Beijing 100084 (China) [Key Laboratory for Thermal Science and Power Engineering of Ministry of Education, Department of Thermal Engineering, Tsinghua University, Beijing 100084 (China); Beijing Key Laboratory of CO2 Utilization and Reduction Technology, Beijing 100084 (China); Liu, Jiangfan; Duan, Minghao; Zong, Anzhou [Key Laboratory for Thermal Science and Power Engineering of Ministry of Education, Department of Thermal Engineering, Tsinghua University, Beijing 100084 (China)] [Key Laboratory for Thermal Science and Power Engineering of Ministry of Education, Department of Thermal Engineering, Tsinghua University, Beijing 100084 (China)

2014-04-15T23:59:59.000Z

487

Galectin-1 Mediates Radiation-Related Lymphopenia and Attenuates NSCLC Radiation Response  

Science Journals Connector (OSTI)

...lymphopenia, which has been linked to poorer survival. Here, we test the hypothesis that radiotherapy-induced lymphopenia is mediated...quantifications were subject to two-tailed, unpaired Student t test to analyze statistical differences between groups. Data are...

Peiwen Kuo; Scott V. Bratman; David B. Shultz; Rie von Eyben; Cato Chan; Ziwei Wang; Carmen Say; Aparna Gupta; Bill W. Loo, Jr; Amato J. Giaccia; Albert C. Koong; Maximilian Diehn; Quynh-Thu Le

2014-11-01T23:59:59.000Z

488

The Role of DNA double-strand break repair in cellular response to low  

NLE Websites -- All DOE Office Websites (Extended Search)

DNA double-strand break repair in cellular response to low DNA double-strand break repair in cellular response to low dose radiation exposure. David J. Chen Division of Molecular Radiation Biology, Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas TX 75390 It has been assumed that molecular pathways that involved in the biological response for low dose of radiation should be similar to those for high dose radiation in general. The low dose-rate effect and DNA double-strand break repair are inextricably linked in mammalian cells. It has been reported that mammalian mutant cells deficient in nonhomologous end join (NHEJ) pathway have little or no cellular recovery when expose to low-dose-rate radiation. Recently, it has also been reported that cells deficient in

489

A low cost adaptive optics system using a membrane mirror  

Science Journals Connector (OSTI)

A low cost adaptive optics system constructed almost entirely of commercially available components is presented.

Paterson, Carl; Munro, I; Dainty, J

2000-01-01T23:59:59.000Z

490

K.K. Gan TWEPP2007 1 Radiation-Hard Optical Link for SLHC  

E-Print Network (OSTI)

irradiation of GaAs PIN from 3 vendors: Optowell, AOC, ULM responsivities will be measured next month 0 2 4 vs Dosage AOC (5 & 10 Gb/s) might survive to SLHC dosage need further analysis after radiation cool

Gan, K. K.

491

Federal Radiological Monitoring and Assessment Center Monitoring Manual Volume 2, Radiation Monitoring and Sampling  

SciTech Connect

The FRMAC Monitoring and Sampling Manual, Volume 2 provides standard operating procedures (SOPs) for field radiation monitoring and sample collection activities that are performed by the Monitoring group during a FRMAC response to a radiological emergency.

NSTec Aerial Measurement Systems

2012-07-31T23:59:59.000Z

492

Local characteristics of heat-radiation superconductor detectors based on high-temperature superconductor films  

Science Journals Connector (OSTI)

Relations are proposed for evaluating the local values of the thermal sensitivity, speed of response, and resolution of a heat radiation detector based on high-temperature superconductor films.

O. S. Esikov; A. I. Krot; I. G. Merinov

1992-06-01T23:59:59.000Z

493

RADIATION ALERT User Manual  

E-Print Network (OSTI)

not contaminate the Inspector by touching it to radioactive surfaces or materials. If contamination is suspected Environmental Area Monitoring 16 Checking for Surface Contamination 16 5 Maintenance 17 Calibration 17, and x-ray radiation. Its applications include: · Detecting and measuring surface contamination

Haller, Gary L.

494

Radiation Source Replacement Workshop  

SciTech Connect

This report summarizes a Radiation Source Replacement Workshop in Houston Texas on October 27-28, 2010, which provided a forum for industry and researchers to exchange information and to discuss the issues relating to replacement of AmBe, and potentially other isotope sources used in well logging.

Griffin, Jeffrey W.; Moran, Traci L.; Bond, Leonard J.

2010-12-01T23:59:59.000Z

495

Solar energy: Radiation nation  

Science Journals Connector (OSTI)

... Australia receives more solar radiation per square metre, on average, than any other continent. Although turning this ... to make use of its heat. We spoke to Australian proponents of two very different solar-thermal systems, both rather confusingly known as ...

Carina Dennis

2006-09-06T23:59:59.000Z

496

Psoriasis and ultraviolet radiation  

SciTech Connect

Prevention and detection screening programs as a public health service in curtailing the ever-increasing incidence of all forms of skin cancer are reviewed. The effect of solar and artificial ultraviolet radiation on the general population and persons with psoriasis is examined. 54 refs.

Farber, E.M.; Nall, L. (Psoriasis Research Institute, Palo Alto, CA (United States))

1993-09-01T23:59:59.000Z

497

Local microwave background radiation  

E-Print Network (OSTI)

An inquiry on a possible local origin for the Microwave Background Radiation is made. Thermal MBR photons are contained in a system called {\\it magnetic bottle} which is due to Earth magnetic field and solar wind particles, mostly electrons. Observational tests are anticipated.

Domingos Soares

2014-11-13T23:59:59.000Z

498

Infrared radiation: Herschel revisited  

Science Journals Connector (OSTI)

The year 2000 marks the 200th anniversary of Herschels discovery of infrared radiation. Using a car light in place of the Sun and a liquid crystal sheet instead of thermometers the experiment is an effective classroom demonstration of invisible light.

Erin E. Pursell; Richard Kozlowski

2000-01-01T23:59:59.000Z

499

Radiation detector spectrum simulator  

DOE Patents (OSTI)

A small battery operated nuclear spectrum simulator having a noise source nerates pulses with a Gaussian distribution of amplitudes. A switched dc bias circuit cooperating therewith generates several nominal amplitudes of such pulses and a spectral distribution of pulses that closely simulates the spectrum produced by a radiation source such as Americium 241.

Wolf, Michael A. (Los Alamos, NM); Crowell, John M. (Los Alamos, NM)

1987-01-01T23:59:59.000Z

500

Radiation detector spectrum simulator  

DOE Patents (OSTI)

A small battery operated nuclear spectrum simulator having a noise source generates pulses with a Gaussian distribution of amplitudes. A switched dc bias circuit cooperating therewith to generate several nominal amplitudes of such pulses and a spectral distribution of pulses that closely simulates the spectrum produced by a radiation source such as Americium 241.

Wolf, M.A.; Crowell, J.M.

1985-04-09T23:59:59.000Z