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1

Bayesian Statistics and Its Application to Quantitative Trait Loci Mapping.  

E-Print Network (OSTI)

??Quantitative trait loci (QTL) mapping is one of the applications of statistics in genetics.This dissertation focuses two problems on QTL mapping which include a newpermutation… (more)

Che, Xiaohong

2011-01-01T23:59:59.000Z

2

Quantitative Trait Loci Analysis of Primary Cell Wall Composition in Arabidopsis1  

E-Print Network (OSTI)

fingerprinting techniques: monosaccharide composition analysis by gas chromatography, xyloglucan oligosaccharideQuantitative Trait Loci Analysis of Primary Cell Wall Composition in Arabidopsis1 Gre´gory Mouille2 trait loci (QTL) analysis was used to identify genes underlying natural variation in primary cell wall

Pauly, Markus

3

Identification of quantitative trait loci and candidate genes for cadmium tolerance in Populus  

Science Conference Proceedings (OSTI)

Understanding genetic variation for the response of Populus to heavy metals like cadmium (Cd) is an important step in elucidating the underlying mechanisms of tolerance. In this study, a pseudo-backcross pedigree of Populus trichocarpa Torr. & Gray and Populus deltoides Bart. was characterized for growth and performance traits after Cd exposure. A total of 16 quantitative trait loci (QTL) at logarithm of odds (LOD) ratio 2.5 were detected for total dry weight, its components and root volume. Major QTL for Cd responses were mapped to two different linkage groups and the relative allelic effects were in opposing directions on the two chromosomes, suggesting differential mechanisms at these two loci. The phenotypic variance explained by Cd QTL ranged from 5.9 to 11.6% and averaged 8.2% across all QTL. A whole-genome microarray study led to the identification of nine Cd-responsive genes from these QTL. Promising candidates for Cd tolerance include an NHL repeat membrane-spanning protein, a metal transporter and a putative transcription factor. Additional candidates in the QTL intervals include a putative homolog of a glutamate cysteine ligase, and a glutathione-S-transferase. Functional characterization of these candidate genes should enhance our understanding of Cd metabolism and transport and phytoremediation capabilities of Populus.

Induri, Brahma R [West Virginia University; Ellis, Danielle R [West Virginia University; Slavov, Goncho T. [West Virginia University; Yin, Tongming [ORNL; Zhang, Xinye [ORNL; Tuskan, Gerald A [ORNL; DiFazio, Steven P [West Virginia University

2012-01-01T23:59:59.000Z

4

An Improved Approach for Mapping Quantitative Trait loci in a Pseudo-Testcross: Revisiting a Poplar Mapping Study  

SciTech Connect

A pseudo-testcross pedigree is widely used for mapping quantitative trait loci (QTL) in outcrossing species, but the model for analyzing pseudo-testcross data borrowed from the inbred backcross design can only detect those QTLs that are heterozygous only in one parent. In this study, an intercross model that incorporates the high heterozygosity and phase uncertainty of outcrossing species was used to reanalyze a published data set on QTL mapping in poplar trees. Several intercross QTLs that are heterozygous in both parents were detected, which are responsible not only for biomass traits, but also for their genetic correlations. This study provides a more complete identification of QTLs responsible for economically important biomass traits in poplars.

Wullschleger, Stan D [ORNL; Wu, Song [St. Jude Children's Research Hospital; Wu, Rongling [ORNL; Yang, Jie [Beijing National Laboratory for Condensed Matter Physics/Chinese Academy of Scie; Huang, Youjun [Zhejiang Forestry University; Li, Yao [West Virginia University; Yin, Tongming [ORNL; Tuskan, Gerald A [ORNL

2010-01-01T23:59:59.000Z

5

An Improved Approach for Mapping Quantitative Trait Loci in a Pseudo-Testcross: Revisiting a Poplar Mapping Study  

SciTech Connect

A pseudo-testcross pedigree is widely used for mapping quantitative trait loci (QTL) in outcrossing species, but the model for analyzing pseudo-testcross data borrowed from the inbred backcross design can only detect those QTLs that are heterozygous only in one parent. In this study, an intercross model that incorporates the high heterozygosity and phase uncertainty of outcrossing species was used to reanalyze a published data set on QTL mapping in poplar trees. Several intercross QTLs that are heterozygous in both parents were detected, which are responsible not only for biomass traits, but also for their genetic correlations. This study provides a more complete identification of QTLs responsible for economically important biomass traits in poplars.

Tuskan, Gerald A [ORNL; Yin, Tongming [ORNL; Wullschleger, Stan D [ORNL; Yang, Jie [Beijing National Laboratory for Condensed Matter Physics/Chinese Academy of Scie; Wu, Song [St. Jude Children's Research Hospital; Huang, Youjun [Zhejiang Forestry University; Li, Yao [West Virginia University; Wu, Rongling [ORNL

2010-01-01T23:59:59.000Z

6

Identification of Quantitative Trait Loci (QTL) and Candidate Genes for Cadmium Tolerance in Populus  

Science Conference Proceedings (OSTI)

Knowledge of genetic variation in response of Populus to heavy metals like cadmium (Cd) is an important step in understanding the underlying mechanisms of tolerance. In this study, a pseudo-backcross pedigree of Populus trichocarpa and Populus deltoides was characterized for Cd exposure. The pedigree showed significant variation for Cd tolerance thus enabling the identification of relatively tolerant and susceptible genotypes for intensive characterization. A total of 16 QTLs at logarithm of odds (LOD) ratio > 2.5, were found to be associated with total dry weight, its components, and root volume. Four major QTLs for total dry weight were mapped to different linkage groups in control (LG III) and Cd conditions (LG XVI) and had opposite allelic effects on Cd tolerance, suggesting that these genomic regions were differentially controlled. The phenotypic variation explained by Cd QTL for all traits under study varied from 5.9% to 11.6% and averaged 8.2% across all QTL. Leaf Cd contents also showed significant variation suggesting the phytoextraction potential of Populus genotypes, though heritability of this trait was low (0.22). A whole-genome microarray study was conducted by using two genotypes with extreme responses for Cd tolerance in the above study and differentially expressed genes were identified. Candidate genes including CAD2 (CADMIUM SENSITIVE 2), HMA5 (HEAVY METAL ATPase5), ATGTST1 (Arabidopsis thaliana Glutathione S-Transferase1), ATGPX6 (Glutathione peroxidase 6), and ATMRP 14 (Arabidopsis thaliana Multidrug Resistance associated Protein 14) were identified from QTL intervals and microarray study. Functional characterization of these candidate genes could enhance phytoremediation capabilities of Populus.

Induri, Brahma R [West Virginia University; Ellis, Danielle R [West Virginia University; Slavov, Gancho [West Virginia University; Yin, Tongming [ORNL; Muchero, Wellington [ORNL; Tuskan, Gerald A [ORNL; DiFazio, Stephen P [West Virginia University

2012-01-01T23:59:59.000Z

7

Copyright 2004 by the Genetics Society of America Quantitative Trait Loci Affecting Starvation Resistance in Drosophila melanogaster  

E-Print Network (OSTI)

. Starvation resistance is a quantitative trait controlled by multiple interacting genes and exhibits Resistance in Drosophila melanogaster Susan T. Harbison,* Akihiko H. Yamamoto,* Juan J. Fanara,*, Koenraad K of strong selection due to a trade-off in resource allocation between reproductive activity and individual

Mackay, Trudy F.C.

8

Identification of Quantitative Trait Loci (QTLs) Associated with Maintenance of Bread Making Quality under Heat Stress in Wheat (Triticum aestivum)  

E-Print Network (OSTI)

The aim of this study was to identify QTLs associated with the maintenance of grain quality following post-anthesis heat stress. A population of 64 F6Halberd X Cutter recombinant inbred lines (RILs) was exposed to either heat stress or control conditions in the greenhouse, starting ten days after anthesis. Grain quality was determined using the sodium dodecyl sulfate (SDS) sedimentation test, a significant predictor of bread baking quality. The percent change in SDS sedimentation test scores between the heat and control populations was used to identify QTLs associated with quality stability. Four QTLs were identified, located one each on chromosomes 1B, 1D, 4A, and 7A. Three of the QTLs, those on 1B, 1D, and 4A, were associated with variations in SDS sedimentation level. The QTL on chromosome 7A was associated with the percent change in SDS sedimentation scores between heat-stressed and control conditions. This indicated a relationship between the identified QTL and quality stability. To confirm the detected QTLs, eighty advanced lines grown at three Texas nurseries were genotyped and tested for relationships between QTL-associated markers, quality traits, and stability of the quality traits. Quality trait stability was estimated using the coefficient of variability (CV%) of quality traits between growing sites. Quality characters analyzed in the advanced lines included kernel hardness, mixograph peak time, kernel weight, flour yield, SDS sedimentation, and grain yield. The analysis showed support for the effect of the QTLs on chromosomes 1B, 1D, and 4A. Further analysis will be needed to confirm the QTL on 7A, in particular. The mapping of additional markers will be necessary. However, the potential importance of this QTL and the abundance of other QTLs detected in this region make it worth investigating.

Beecher, Francis Ward

2009-08-01T23:59:59.000Z

9

Identification of quantitative trait loci affecting ectomycorrhizal symbiosis in an interspecific F1 poplar cross and differential expression of genes in ectomycorrhizas of the two parents: Populus deltoides and Populus trichocarpa  

SciTech Connect

A Populus deltoides Populus trichocarpa F1 pedigree was analyzed for quantitative trait loci (QTLs) affecting ectomycorrhizal development and for microarray characterization of gene networks involved in this symbiosis. A 300 genotype progeny set was evaluated for its ability to form ectomycorrhiza with the basidiomycete Laccaria bicolor. The percentage of mycorrhizal root tips was determined on the root systems of all 300 progeny and their two parents. QTL analysis identified four significant QTLs, one on the P. deltoides and three on the P. trichocarpa genetic maps. These QTLs were aligned to the P. trichocarpa genome and each contained several megabases and encompass numerous genes. NimbleGen whole-genome microarray, using cDNA from RNA extracts of ectomycorrhizal root tips from the parental genotypes P. trichocarpa and P. deltoides, was used to narrow the candidate gene list. Among the 1,543 differentially expressed genes (p value 0.05; 5.0-fold change in transcript level) having different transcript levels in mycorrhiza of the two parents, 41 transcripts were located in the QTL intervals: 20 in Myc_d1, 14 in Myc_t1, and seven in Myc_t2, while no significant differences among transcripts were found in Myc_t3. Among these 41 transcripts, 25 were overrepresented in P. deltoides relative to P. trichocarpa; 16 were overrepresented in P. trichocarpa. The transcript showing the highest overrepresentation in P. trichocarpa mycorrhiza libraries compared to P. deltoides mycorrhiza codes for an ethylene-sensitive EREBP-4 protein which may repress defense mechanisms in P. trichocarpa while the highest overrepresented transcripts in P. deltoides code for proteins/genes typically associated with pathogen resistance.

Labbe, Jessy L [ORNL; Jorge, Veronique [INRA, Nancy, France; Vion, Patrice [INRA, Nancy, France; Marcais, Benoit [INRA, Nancy, France; Bastien, Catherine [INRA, Orleans, France; Tuskan, Gerald A [ORNL; Martin, Francis [INRA, Nancy, France; Le Tacon, F [UMR, France

2011-01-01T23:59:59.000Z

10

Bayesian Statistics and Its Application to Quantitative Trait Loci Mapping  

E-Print Network (OSTI)

2.2.4 Bayesian inference . . . . . . . . . . . . . . . . .distributions for bayesian inference. Journal of the RoyalIllustration of bayesian inference in normal data models

Che, Xiaohong

2011-01-01T23:59:59.000Z

11

Bayesian Statistics and Its Application to Quantitative Trait Loci Mapping  

E-Print Network (OSTI)

2.2.4 Bayesian inference . . . . . . . . . . . . . . . . .and Genome Selection in Bayesian Shrinkage Analy- sis 3.11.3.2 Bayesian Shrinkage Method and Permutation Test for

Che, Xiaohong

2011-01-01T23:59:59.000Z

12

Candidate genes for chromosomes 6 and 10 quantitative trait loci for age-related retinal degeneration in mice  

E-Print Network (OSTI)

), complement factor B (CFB), and complement component 2 (C2), Chemokine (C-X3-C motif) receptor 1 (CX3CR1), Age to permanent exposure to reactive oxygen species generated by the absorption of light. Genes involved in gene expression should reflect an adjustment of blood flow for the oxygen requirement of the retina

Dahlquist, Kam D.

13

Quantitative Mapping of a Digenic Behavioral Trait Implicates Globin Variation in C. elegans  

E-Print Network (OSTI)

inhumansandbehav- ioral traits in animals (Kendler, 2001; Kendler and Greenspan, 2006; Flint, 2003), but only a few effects, and many genes with small effects (Flint, 2003; Mackay, 2004; Kendler and Greenspan, 2006 a QTL to the caus- ative mutation is verydifficult (Mackay, 2004; Mottand Flint,2008; Flint, 2003

Bargmann, Cori

14

Genetic Mapping of Quantitative Trait Loci Associated with Bioenergy Traits, and The Assessment of Genetic Variability in Sweet Sorghum (Sorghum bicolor (L.). Moench).  

E-Print Network (OSTI)

??Sweet sorghum, a botanical variety of sorghum is a potential source of bioenergy because high sugar levels accumulate in its stalks. The objectives of this… (more)

Lekgari, Aatshwaelwe Lekgari

2010-01-01T23:59:59.000Z

15

Identification of two interacting quantitative trait loci controlling for condensed tannin in sorghum grain and grain quality analysis of a sorghum diverse collection.  

E-Print Network (OSTI)

??Tannin, a second metabolic product in sorghum, has been directly related to resistance to insects and birds. Tannin also impacts sorghum nutritional value. Previous studies… (more)

Xiang, Wenwen

2009-01-01T23:59:59.000Z

16

Quantitative genetics of growth, carcass-quality traits, and disease resistance in hybrid striped bass (Morone chrysops [female] x Morone saxatilis [male])  

E-Print Network (OSTI)

A 10 x 10 factorial mating design and a ‘common-garden’ rearing approach were employed to examine genetic effects and heritability of growth, carcass-quality traits, and disease resistance, important production traits in the aquaculture of hybrid striped bass (? white bass, Morone chrysops, crossed with ?striped bass, Morone saxatilis). Genotypes at four to ten nuclear-encoded microsatellites were used for parentage assignment and a general, linear-mixed model and a Restricted Maximum Likelihood (REML) algorithm were used to estimate variance components associated with dam, sire, and dam x sire interaction effects. Dam and sire effect on juvenile growth (weight, length and growth rates) were significant, whereas dam by sire interaction effect was not. Estimates of broad-sense heritability for growth, based on family means (h2 f), in dams ranged from 0.60 ± 0.20 to 0.82 ± 0.10 and in sires ranged from 0.43 ± 0.20 to 0.75 ± 0.18. High correlations were found between growth rates measured at two time intervals. Estimates of general combining ability for growth rates differed significantly among dams and among sires, whereas estimates of specific combining ability for each dam × sire combination did not differ significantly from zero. These results suggest that additive-effect genes contributed to the differences in juvenile growth. Dam and sire effect on fillet weight were significant; dam effect on liver weight and sire effect on total viscera weight were also significant. Dam and sire effect on hepatosomatic index and viscerasomatic index were significant, as was dam and sire interaction effect on viscerasomatic index. Phenotypic and genetics correlations between body weight and carcass-quality traits were high (0.85 - 1.00). Phenotypic correlations between body weight and standardized carcass-quality traits were positive but low, ranging from 0.07 to 0.19. Resistance to S. iniae was assessed in a challenge experiment, using the 10 dam x 10 sire factorial mating design. A significant effect of sire on resistance to S. iniae was found, and offspring from one sire had a 2.4 times higher probability of dying than offspring from the ‘average’ sire. Genetic effects on the immune-response parameters and on stress-response parameters assessed were non-significant.

Wang, Xiaoxue

2006-12-01T23:59:59.000Z

17

Quantitative Trait Locus (QTL) Mapping of Transpiration Efficiency Related to Pre-flower Drought Tolerance in Sorghum [Sorghum bicolor (L.) Moench  

E-Print Network (OSTI)

There is an increasing need to improve crop water-use efficiency (WUE) (ratio of whole-plant biomass to cumulative transpiration) due to decreased water availability and increased food and energy demands throughout the world. The objective of the study was to estimate the genetic variation and genetic basis for transpiration efficiency A:E (CO2 assimilation rate (A) divided by transpiration rate (E)) trait and its relationship to WUE related to pre-flower drought tolerance in recombinant inbred lines (RILs) of sorghum and associated QTLs. A greenhouse study was conducted at Bushland, TX, 2008, using 71 RILs derived from cross of Tx430 x Tx7078. A randomized complete block experimental design was used, with both genotype and water regime (40 and 80 percent water regime) as experimental factors, and four replications. Genotype had a significant effect on A, E and A:E under both the environments. Among the RILs, entry means for A:E ranged from 1.58 to 3.07 mmol CO2 mol^-1 H2O and 1.18 to 4.36 mmol CO2 mol^-1 H2O under 80 percent and 40 percent water regime, respectively. Heritability estimates based on individual environments for A:E , A and E were 0.77, 0.45 and 0.37 under 80 percent water regime and 0.90, 0.33 and 0.71 under 40 percent water regime, respectively. A genetic map was constructed by digital genotyping method using Illumina GAII sequencer with 261 informative indel/ single-nucleotide polymorphism (SNP's) markers distributed over 10 linkage groups. Three significant QTLs associated with transpiration efficiency were identified; two on SBI-09 and one on SBI-10 with one logarithmic of odds (LOD) interval length ranging from 5.3 to 5.7 cM and accounting for 17 percent - 21 percent of the phenotypic variation. In field and greenhouse evaluation of agronomic of traits at College Station and Halfway, TX, 91 QTL that control variation in six major agronomic traits such as plant height, flowering, biomass, leaf area, leaf greenness and stomatal density were identified. Co-localization of transpiration efficiency QTLs with agronomic traits such as leaf area, biomass, leaf width and stomatal density indicated that these agronomically important QTLs can be used for further improving the sorghum performance through marker assisted selection (MAS) under pre-flowering drought stress conditions.

Heraganahally Kapanigowda, Mohankumar

2011-05-01T23:59:59.000Z

18

Empirical Bayesian LASSO-logistic regression for multiple binary trait locus mapping  

E-Print Network (OSTI)

Appl Genet 11. Yi N, Xu S: Bayesian mapping of quantitativeS, Pomp D, Yandell BS: Bayesian mapping of genomewideThreadgill DW, Zou F: Bayesian multiple quantitative trait

Huang, Anhui; Xu, Shizhong; Cai, Xiaodong

2013-01-01T23:59:59.000Z

19

Designer Sorghum Combining the High Digestibility and Waxy Grain Traits of Sorghum for Improved Nutrition Bioethanol Beer Feed and Food Products  

E-Print Network (OSTI)

Sorghum (Sorghum bicolor (L). Moench) is used for human consumption in parts of Africa and Asia and as an animal feed mainly in the U.S. Though sorghum grain contains higher amounts of protein than other cereal grains such as wheat and corn, it is not as readily available for enzyme degradation in humans and animals. Protein body matrices called kafirins surround the starch granules in sorghum. Because the protein is less digestible, the starch is also less digestible for biofuel production. However variation for this trait exists and the line P850029 has a higher protein digestibility compared to other normal grain sorghum lines. This increase in digestibility of protein is due to the rearrangement of the kafirins in the prolamin protein bodies where, the ?-kafirins are rearranged in the seed endosperm and the amount of ?-kafirin in the grain is also reduced. The assay to phenotype the HD trait is time consuming and unpredictable. So identifying a quantitative trait loci (QTL) controlling the protein digestibility trait in sorghum would be beneficial in breeding. A recombinant inbred lines (RILs) population derived from P850029 x ‘Sureno’, were developed and used to map QTL regulating the protein digestibility trait. A single QTL was identified on chromosome 1 between Xtxp43 and Xtxp329. Validation of the identified QTL was done on heterogenous inbred families (HIFs). The results validate the same QTL identified on the RIL population on chromosome 1. Later the high digestibility trait (HD) was integrated with the Waxy trait in sorghum. The Waxy (WX) sorghums have starch completely in the form of amylopectin. The effect of endosperm type on ethanol yield and fermentation efficiencies was studied among HD, WX and HD-WX lines. The HD-WX lines fermented in a shorter time i.e. completed fermentation in 48 h and their fermentation efficiencies were also higher around 90%. The DDGS of the HD-WX lines also had lower residual starch content and 50% higher amino acid lysine content when compared to wildtype sorghum. Moreover, the relation between endosperm traits and grain yield in sorghum has not been fully explored. In this study, we compared the yield and yield components of four unique endosperm phenotypes, HD, WX, HD-WX and wildtype lines. A total of 100 F2:4 derived recombinant inbred lines population from a cross between Tx2907/P850029 were selected with 25 lines from each HD, WX, HD-WX and wild-type line were included in the study. These lines were grown in three replications in College Station and Halfway, Texas in a randomized complete block design. The results show that there are no significant differences in the grain yield.

Jampala, Babitha

2012-05-01T23:59:59.000Z

20

Development and Validation of Marker-Aided Selection Methods for Wood Property Traits in Loblolly Pine and Hybrid Poplar  

SciTech Connect

Wood properties influence pulp and paper quality. Certainly, overall pulp yields are directly related to the cellulose content, changes in hemicellulose content are associated with changes in pulp cohesiveness, and pulping efficiency is related to lignin content. Despite the importance of wood properties on product quality, little progress has been made in improving such traits because current methods of assessing wood and fiber characteristics are time-consuming, expensive, and often imprecise. Genetic improvement of wood and fiber properties has been further hampered by the large size of trees, delayed reproductive maturity and long harvest cycles. Recent developments in molecular genetics will help overcome the physical, economic and biological constraints in assessing and improving wood properties. Genetic maps consisting of numerous molecular markers are now available for loblolly pine and hybrid poplar. Such markers/maps may be used as part of a marker-aided selection and breeding effort or to expedite the isolation and characterization of genes and/or promoters that directly control wood properties. The objectives of this project are: (1) to apply new and rapid analytical techniques for assessing component wood properties to segregating F2 progeny populations of loblolly pine and hybrid poplar, (2) to map quantitative trait loci and identify molecular markers associated with wood properties in each of the above species and (3) to validate marker-aided selection methods for wood properties in loblolly pine and hybrid poplar.

Tuskan, G.A.

2001-06-20T23:59:59.000Z

Note: This page contains sample records for the topic "quantitative trait loci" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


21

Expanding the US Core CODIS Loci  

Science Conference Proceedings (OSTI)

... GlobalFiler (Life Technologies) – PowerPlex Fusion (Promega) Page 3. Need for Additional Loci ... Page 22. Promega PowerPlex FUSION FGA A ...

2013-02-25T23:59:59.000Z

22

Bioinformatics-Based Identification  

NLE Websites -- All DOE Office Websites (Extended Search)

energy feedstock. Keywords Populus . Whole-genome duplication . Quantitative trait loci . Wood chemistry . Syringyl lignin . Guaiacyl lignin . Biofuels Abbreviations QTL...

23

Traits and Multiple Genes  

NLE Websites -- All DOE Office Websites (Extended Search)

Traits and Multiple Genes Traits and Multiple Genes Name: Frank Location: N/A Country: N/A Date: N/A Question: Please, could you give me an example of how human traits are controlled by more than one pair of alleles? Replies: Your question is just a bit vague, there are different answers depending on just what your question is. I will answer it in terms of polygenic traits also known as additive alleles. When you think of traits such as skin color, hair color and eye color, or traits where there is a wide range of phenotypes they are usually under the control of more than one pair of alleles. These alleles can even be on different chromosomes! Each pair of additive alleles adds to the phenotype. For instance in the case of skin color, scientists now believe that 3 genes control skin color. You then get 3 sets from your mother and 3 from your father for 6 possibilities. If all 6 of the alleles are for dark skin, you will have the darkest possible skin. If you have 5 dark alleles and one light, you will have very dark skin. If you have all 6 light alleles then you will have the lightest skin possible. Is it possible to have a child that is light skinned when both parents are dark-skinned? Well, not if both have all 6 dark alleles, but if they have some light alleles and the child inherits all of the possible light alleles available, then yes, the child could have lighter skin than either parent. It is now believed that eye color is not simply brown being dominant over blue because how many people do you know that have the same shade of brown or blue eyes? Eye color must also be polygenic.

24

Differential detection of genetic loci underlying stem and root lignin content in Populus  

Science Conference Proceedings (OSTI)

For simultaneous applications directed towards improved pulp yields, enhanced bioethanol production and increased carbon sequestration, it would be desirable to reduce lignin in the harvested stem while increasing the lignin content in nonharvested roots. In this study, we established a comprehensive genetic map with a large number of progeny from a three-generation hybrid Populus intercross, and phenotyped the lignin content, S/G ratio and 28 cell wall subcomponents both in stems and roots for the mapping individuals. Phenotypic analysis revealed that lignin content and syringyl-to-guaiacyl (S/G) ratio using pyrolysis molecular beam mass spectroscopy (pyMBMS) varied among mapping individuals. Phenotypic analysis revealed that stem lignin content is significantly higher than that in root and the quantified traits can be classified into four distinct groups, with strong correlations observed among components within organs. Altogether, 179 coordinating QTLs were detected, and they were co-localized into 49 genetic loci, 27 of which appear to be pleiotropic. Many of the detected genetic loci were detected differentially in stem and root. This is the first report of separate genetic loci controlling cell wall phenotypes above and below ground. These results suggest that it may be possible to modify lignin content and composition via breed and/or engineer as a means of simultaneously improving Populus for cellulosic ethanol production and carbon sequestration.

Tuskan, Gerald A [ORNL; Yin, Tongming [ORNL; Zhang, Xinye [ORNL; Gunter, Lee E [ORNL; Ranjan, Priya [ORNL; Sykes, Robert [National Renewable Energy Laboratory (NREL); Davis, Dr. Mark F. [National Renewable Energy Laboratory (NREL); Wullschleger, Stan D [ORNL

2010-11-01T23:59:59.000Z

25

Quantitative languages  

Science Conference Proceedings (OSTI)

Quantitative generalizations of classical languages, which assign to each word a real number instead of a Boolean value, have applications in modeling resource-constrained computation. We use weighted automata (finite automata with transition weights) ... Keywords: Model checking, expressiveness, quantitative verification, weighted automata

Krishnendu Chatterjee; Laurent Doyen; Thomas A. Henzinger

2010-07-01T23:59:59.000Z

26

Quantitative Thermography  

NLE Websites -- All DOE Office Websites (Extended Search)

Quantitative Thermography Quantitative Thermography Images collected with infrared thermography can be very useful for gaining insight into thermal phenomena such as thermal bridging and natural convection. But as a research tool it is even more valuable to extract numerical data from the images and produce maps of surface temperature. This is called quantitative infrared thermography and can be very challenging. We have developed procedures that allow collecting and processing the infrared data to enable obtaining results that are as accurate as possible. The main difficulties in using infrared to measure temperature are correcting the measurement for reflected radiation and proper referencing of the relative radiometric measurement. Efforts are underway to develop standardized test procedures for using infrared to quantify surface temperatures in the types of thermal test chambers used to test building products. But for now, information on how we perform quantitative thermography is available in some of our technical papers. One of these papers presents temperature results for a series of insulated glazing units. This is an example of our goal to make available a database of surface temperatures results for various types of windows. These data sets are available for download at the link below. The data are for the warm side surface of various types of air-filled insulating glazing units subjected to ASHRAE winter design conditions and are similar to the graph below.

27

An Evolutionary Reduction Principle for Mutation Rates at Multiple Loci  

E-Print Network (OSTI)

A model of mutation rate evolution for multiple loci under arbitrary selection is analyzed. Results are obtained using techniques from Karlin (1982) that overcome the weak selection constraints needed for tractability in prior studies of multilocus event models. A multivariate form of the reduction principle is found: reduction results at individual loci combine topologically to produce a surface of mutation rate alterations that are neutral for a new modifier allele. New mutation rates survive if and only if they fall below this surface - a generalization of the hyperplane found by Zhivotovsky et al. (1994) for a multilocus recombination modifier. Increases in mutation rates at some loci may evolve if compensated for by decreases at other loci. The strength of selection on the modifier scales in proportion to the number of germline cell divisions, and increases with the number of loci affected. Loci that do not make a difference to marginal fitnesses at equilibrium are not subject to the reduction principle, and under fine tuning of mutation rates would be expected to have higher mutation rates than loci in mutation-selection balance. Other results include the nonexistence of 'viability analogous, Hardy-Weinberg' modifier polymorphisms under multiplicative mutation, and the sufficiency of average transmission rates to encapsulate the effect of modifier polymorphisms on the transmission of loci under selection. A conjecture is offered regarding situations, like recombination in the presence of mutation, that exhibit departures from the reduction principle. Constraints for tractability are: tight linkage of all loci, initial fixation at the modifier locus, and mutation distributions comprising transition probabilities of reversible Markov chains.

Lee Altenberg

2009-09-14T23:59:59.000Z

28

Genetic dissection of bioenerrgy traits in sorghum  

Science Conference Proceedings (OSTI)

Specific Objectives: 1. To identify the gene(s) underlying a major QTL for stem sugar concentration located on chromosome 3. 2. To identify QTL for stem juice volume and stalk sugar concentration and to identify the underlying genes. 3. To classify 60 novel sorghum bmr mutants from the USDA TILLING population in allelic groups based on cell wall chemistry and allelism tests. 4. To select representative bmr mutants from each allelic group and selected NIR spectral mutants for their potential value as feedstock for ethanol production. 5. To clone and characterize those Bmr genes that represent loci other than Bmr12 and Bmr6 using a mapping and a candidate gene approach. Objective 1 The experiments for this objective are largely complete and the data have been analyzed. Data interpretation and follow-up experiments are still in progress. A manuscript is in preparation (Vermerris et al.; see publication list for full details). The main results are: 1) 16 cDNA libraries were prepared and sequenced at Cornell University. The libraries represent internode tissue and flag leaf tissue at booting, internode tissue and peduncle at soft-dough stage, from two plants per sampling time with the Rio allele for the QTL on chromosome 3, and two plants with the BTx623 allele on chromosome 3 (4 tissues x 2 genotypes x 2 replicates) 2) 480 million 86-nucleotide reads were generated from four lanes of Illuminia HiSeqII 3) 74% of the reads could be mapped to the sorghum transcriptome, indicative of good sequence quality 4) Of the 216 genes within the QTL, 17 genes were differentially expressed among plants with and without the Rio QTL. None of these 17 genes had obvious roles in sucrose metabolism 5) Clustering algorithms identified a group of 721 co-expressed genes. One of these genes is a sucrose synthase gene. This cluster also contains 10 genes from the QTL. 6) Among these co-expressed genes are regulatory genes for which knock-out lines in Arabidopsis have been obtained. Analysis of these lines is in progress. Objective 2 The experiments from this objective have been completed and the data were published in the journal Crop Science by Felderhoff et al. (2012). A second publication by Felderhoff et al. is in progress (see publication list for full details). The experiments were based on a mapping population derived from the sweet sorghum 'Rio' and the dry-stalk grain sorghum BTx3197. The main findings were: 1) The apparent juiciness of the sorghum stalk, based on the appearance of a cut stem surface (moist vs. pithy), is not representative of the moisture content of the stalk. This was surprising, as pithy stalks have been associated with low moisture content. This means that in order to assess 'juiciness', a different evaluation needs to be used, for example by removing juice with a roller press or by measuring the difference in mass between a fresh and dried stalk segment. 2) A total of five QTLs associated with juice volume (corrected for height) or moisture content were identified, but not all QTLs were detected in all environments, providing evidence for genotype x environment interactions. This finding complicates breeding for juice volume using marker-assisted selection. 3) The QTL for sugar concentration identified on chromosome 3, and the subject of Objective 1, was confirmed in this mapping population, but unlike in previous studies (Murray et al., 2008), the presence of this QTL was associated with negative impacts on agronomic performance (fresh and dry biomass yield, juice yield). Consequently, introgression of the Brix QTL from Rio as part of a commercial breeding program will require monitoring of the precise impacts of this QTL on agronomic performance. 4) The absence of dominance effects for the Brix trait (= sugar concentration) indicated that Brix must be high in both parents to produce high Brix in hybrids. This means an extra constraint on the development of hybrid parents. With the results from Objective 1, the selection of progeny containing favorable alleles for sugar concentration is expected to be more efficient.

Vermerris, Wilfred; Kresovich, Stephen; Murray, Seth; Pedersen, Jeffery; Rooney, William; Sattler, Scott.

2012-06-15T23:59:59.000Z

29

Using Extended Genealogy to Estimate Components of Heritability for 23 Quantitative and Dichotomous Traits  

E-Print Network (OSTI)

Important knowledge about the determinants of complex human phenotypes can be obtained from the estimation of heritability, the fraction of phenotypic variation in a population that is determined by genetic factors. Here, ...

Zaitlen, Noah

30

Quantitative Imaging in Cell Biology  

E-Print Network (OSTI)

Quantitative! imaging! in! biology! is! concerned! with!Quantitative! imaging! in! biology! is! concerned! with!advances! in! cell! biology! by! enabling! the! tracking!

Yassif, Jaime

2012-01-01T23:59:59.000Z

31

Genet. Sel. Evol. 37 (2005) 215228 215 c INRA, EDP Sciences, 2005  

E-Print Network (OSTI)

Original article Confirmation of quantitative trait loci affecting fatness in chickens Danyel G.J. JENNENa intercross line / chicken / fatness traits 1. INTRODUCTION Fat deposition is an important trait for the percentage of abdominal fat at the age of 10 weeks on chicken chromosome 1. This QTL explained about 18

Recanati, Catherine

32

Genomic architecture of risk loci associated with autoimmunity (7th Annual SFAF Meeting, 2012)  

SciTech Connect

Ward Wakeland on "Genomic architecture of risk loci associated with autoimmunity" at the 2012 Sequencing, Finishing, Analysis in the Future Meeting held June 5-7, 2012 in Santa Fe, New Mexico.

Wakeland, Ward [University of Texas Southwestern Medical Center

2012-06-01T23:59:59.000Z

33

1 The Evolution of Gall Traits in the Fordinae (Homoptera)  

E-Print Network (OSTI)

, they represent all gall types and crucial life history traits that are found in the Fordinae (Wool, 1984 belonging to the genus Baizongiini, are included in the present study (Table 1; Table 1 Life history traits in Koach and Wool, 1977). The life cycle of the Fordinae includes sexual and asexual reproduction

Inbar, Moshe

34

Genet. Sel. Evol. 38 (2006) 8597 85 c INRA, EDP Sciences, 2005  

E-Print Network (OSTI)

article Mapping quantitative trait loci affecting fatness and breast muscle weight in meat-type chicken-family residual standard deviation. quantitative trait locus / abdominal fat / breast muscle /chicken New address chickens have better protein efficiency than fat ones [15] which also ex- crete more nitrogen [5]. More

Recanati, Catherine

35

Primary enzyme quantitation  

DOE Patents (OSTI)

The disclosure relates to the quantitation of a primary enzyme concentration by utilizing a substrate for the primary enzyme labeled with a second enzyme which is an indicator enzyme. Enzyme catalysis of the substrate occurs and results in release of the indicator enzyme in an amount directly proportional to the amount of primary enzyme present. By quantifying the free indicator enzyme one determines the amount of primary enzyme present.

Saunders, G.C.

1982-03-04T23:59:59.000Z

36

The Evolution and Stability of Cooperative Traits  

E-Print Network (OSTI)

Recent works in multi-agent systems have identified agent behaviors that can develop and sustain mutually beneficial cooperative relationships with like-minded agents and can resist exploitation from selfish agents. Researchers have proposed the use of a probabilistic reciprocity scheme that uses summary information from past interactions to decide whether or not to honor a request for help from another agent. This behavior has been found to be close to optimal in homogeneous groups and outperform exploiters in mixed groups. A major shortcoming of these experiments, however, is that the composition of the group in term of agent behaviors is fixed. We believe that real-life rational agents, on the contrary, will change their behaviors based on observed performances of di#erent behavioral traits with the goal of maximizing performance. In this paper, we present results from experiments on two distinct domains with population groups whose behavioral composition changes based on the performance of the agents. Based on the experimental results, we identify ecological niches for variants of exploitative selfish agents and robust reciprocative agents.

Sandip Sen; Partha Sarathi Dutta

2002-01-01T23:59:59.000Z

37

Bioinformatics-Based Identification of Candidate Genes from QTLs Associated with Cell Wall Traits in Populus  

DOE Green Energy (OSTI)

Quantitative trait locus (QTL) studies are an integral part of plant research and are used to characterize the genetic basis of phenotypic variation observed in structured populations and inform marker-assisted breeding efforts. These QTL intervals can span large physical regions on a chromosome comprising hundreds of genes, thereby hampering candidate gene identification. Genome history, evolution, and expression evidence can be used to narrow the genes in the interval to a smaller list that is manageable for detailed downstream functional genomics characterization. Our primary motivation for the present study was to address the need for a research methodology that identifies candidate genes within a broad QTL interval. Here we present a bioinformatics-based approach for subdividing candidate genes within QTL intervals into alternate groups of high probability candidates. Application of this approach in the context of studying cell wall traits, specifically lignin content and S/G ratios of stem and root in Populus plants, resulted in manageable sets of genes of both known and putative cell wall biosynthetic function. These results provide a roadmap for future experimental work leading to identification of new genes controlling cell wall recalcitrance and, ultimately, in the utility of plant biomass as an energy feedstock.

Ranjan, Priya [ORNL; Yin, Tongming [ORNL; Zhang, Xinye [ORNL; Kalluri, Udaya C [ORNL; Yang, Xiaohan [ORNL; Jawdy, Sara [ORNL; Tuskan, Gerald A [ORNL

2009-11-01T23:59:59.000Z

38

Quantitive DNA Fiber Mapping  

SciTech Connect

Several hybridization-based methods used to delineate single copy or repeated DNA sequences in larger genomic intervals take advantage of the increased resolution and sensitivity of free chromatin, i.e., chromatin released from interphase cell nuclei. Quantitative DNA fiber mapping (QDFM) differs from the majority of these methods in that it applies FISH to purified, clonal DNA molecules which have been bound with at least one end to a solid substrate. The DNA molecules are then stretched by the action of a receding meniscus at the water-air interface resulting in DNA molecules stretched homogeneously to about 2.3 kb/{micro}m. When non-isotopically, multicolor-labeled probes are hybridized to these stretched DNA fibers, their respective binding sites are visualized in the fluorescence microscope, their relative distance can be measured and converted into kilobase pairs (kb). The QDFM technique has found useful applications ranging from the detection and delineation of deletions or overlap between linked clones to the construction of high-resolution physical maps to studies of stalled DNA replication and transcription.

Lu, Chun-Mei; Wang, Mei; Greulich-Bode, Karin M.; Weier, Jingly F.; Weier, Heinz-Ulli G.

2008-01-28T23:59:59.000Z

39

A dyadic-interactional perspective of implicit trait policies  

E-Print Network (OSTI)

The dyadic-interactional perspective of personality suggests that behavior is a function of both stable personality traits and the dynamic interpersonal environment. According to this theory, interpersonal behavior generally follows the principle of complementarity where behavior tends to be complementary on a dimension of dominance-submissiveness and supplementary on a dimension of warmth-coldness. Implicit trait policies are thought to influence judgments of behavioral effectiveness and be influenced by personality traits. The current study examines the dyadic-interactional perspective using a situational judgment test (SJT) method in order to more fully understand both the relationship between personality traits and behavior but also to better understand the basic assumptions of the dyadic-interactional perspective. A 24-situation SJT was developed by the author to measure appropriate and inappropriate situations along the dimensions of dominance and warmth. Ten advanced psychology graduate students served as expert raters. Personality scales and the SJT were completed by 317 undergraduates for course credit. Interpersonal skills rated by 117 of the participants’ friends served as a performance criterion for Hypothesis 5. Results support a congruence effect where the fit between response and trait warmth has a positive effect on judgments of behavioral effectiveness. Although a quadratic implicit trait policy effect was observed, results did not support a congruence effect for dominance. Interpersonal rigidity was shown to moderate the effect of both dominant and warm responses but was not shown to moderate the effect of traits. Complementarity hypotheses were not supported, likely due to range restriction of analyzed situations. Exploratory analyses revealed effects in support of interpersonal theory. Situations and responses influenced perceived behavioral effectiveness in accordance with the propositions of interpersonal theory. Situational appropriateness was identified as a moderator of the relationship between situations and responses. Situational judgment test scores were scored in accordance with interpersonal theory. Scores were not shown to observable interpersonal skills as hypothesized, correlating with only one 4-item subscale. Results extend both implicit trait policies and interpersonal theory. Implications, limitations, and future research directions are discussed.

Benzer, Justin Kane

2008-08-01T23:59:59.000Z

40

Quantitative Luminescence Imaging System  

SciTech Connect

The goal of the MEASUREMENT OF CHEMILUMINESCENCE project is to develop and deliver a suite of imaging radiometric instruments for measuring spatial distributions of chemiluminescence. Envisioned deliverables include instruments working at the microscopic, macroscopic, and life-sized scales. Both laboratory and field portable instruments are envisioned. The project also includes development of phantoms as enclosures for the diazoluminomelanin (DALM) chemiluminescent chemistry. A suite of either phantoms in a variety of typical poses, or phantoms that could be adjusted to a variety of poses, is envisioned. These are to include small mammals (rats), mid-sized mammals (monkeys), and human body parts. A complete human phantom that can be posed is a long-term goal of the development. Taken together, the chemistry and instrumentation provide a means for imaging rf dosimetry based on chemiluminescence induced by the heat resulting from rf energy absorption. The first delivered instrument, the Quantitative Luminescence Imaging System (QLIS), resulted in a patent, and an R&D Magazine 1991 R&D 100 award, recognizing it as one of the 100 most significant technological developments of 1991. The current status of the project is that three systems have been delivered, several related studies have been conducted, two preliminary human hand phantoms have been delivered, system upgrades have been implemented, and calibrations have been maintained. Current development includes sensitivity improvements to the microscope-based system; extension of the large-scale (potentially life-sized targets) system to field portable applications; extension of the 2-D large-scale system to 3-D measurement; imminent delivery of a more refined human hand phantom and a rat phantom; rf, thermal and imaging subsystem integration; and continued calibration and upgrade support.

Batishko, C.R.; Stahl, K.A.; Fecht, B.A.

1992-12-31T23:59:59.000Z

Note: This page contains sample records for the topic "quantitative trait loci" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


41

Traits: A mechanism for fine-grained reuse  

Science Conference Proceedings (OSTI)

Inheritance is well-known and accepted as a mechanism for reuse in object-oriented languages. Unfortunately, due to the coarse granularity of inheritance, it may be difficult to decompose an application into an optimal class hierarchy that maximizes ... Keywords: Languages, Smalltalk, inheritance, mixins, multiple inheritance, reuse, traits

Stéphane Ducasse; Oscar Nierstrasz; Nathanael Schärli; Roel Wuyts; Andrew P. Black

2006-03-01T23:59:59.000Z

42

QTLs for Energy Related Traits in a Sweet × Grain RIL Sorghum [Sorghum bicolor (L.) Moench] Population  

E-Print Network (OSTI)

Recent initiatives for biofuel production have increased research and development of sweet sorghum. Currently, the initial major limitation to integrating sweet sorghum into existing production systems is the lack of sweet sorghum hybrids adapted to industrial production systems. Hybrid development is now underway, and the application of genetic markers can be used to define the genetic basis of sugar yield and its components, as well as reduce the time required to deliver new sweet sorghum hybrids to market. The purpose of this research was to further characterize the genetic components that influence sweet sorghum productivity, agronomics, and composition. Specifically, a grain x sweet sorghum recombinant inbred line (RIL) population developed for quantitative trait locus (QTL) analysis related to sugar production was evaluated for 24 phenotypic traits including brix, percent moisture, and biomass yield across four environments. The 185 F4 RILs were derived from the parents 'BTx3197' and 'Rio', which are pithy stalk grain and juicy stalk sweet sorghums respectively. Following screening, two genetic maps were constructed with 372 and 381 single nucleotide polymorphisms (SNPs) evaluated using an Illumina GoldenGate assay. Analysis of the data in QTL Cartographer revealed a major and previously reported QTL for soluble solids on chromosome 3, but in contrast to previous studies, this QTL co-localized with other QTLs that have a negative influence on biomass and seed production. Therefore, selection for this QTL may not be advantageous. Because only a few QTLs for percent moisture were found, the results indicated that the pithy stalk phenotype does not have a major effect on percent moisture as measured in this study. Thus, breeding for high or low moisture content will be more challenging than previously expected. The absence of dominance effects indicated that brix must be high in both parents to produce high brix in the hybrid.

Felderhoff, Terry

2011-08-01T23:59:59.000Z

43

GENIUS LOCI.  

E-Print Network (OSTI)

??I attempt to capture the simple and fleeting beauty of Washington, DC, before it folds into time. In my representational paintings and monotypes, I want… (more)

Corcoran, Cecily

2012-01-01T23:59:59.000Z

44

ASSOCIATION OF SINGLE NUCLEOTIDE POLYMORPHISMS WITH PHENOTYPIC PRODUCTION TRAITS IN BROILER CHICKENS.  

E-Print Network (OSTI)

??This research investigated the association between SNPs and phenotypic production traits in fat and lean chicken broiler lines. In previous research, eleven SNPs in the… (more)

Liu, Xuan

2009-01-01T23:59:59.000Z

45

A Correlational Investigation of Early Childhood Experiences and Adult Personality Traits.  

E-Print Network (OSTI)

??Embedded within the definition of a personality disorder is the notion that the traits that define each condition have been pervasive and distinct throughout an… (more)

Bonanno, Steven

2005-01-01T23:59:59.000Z

46

Identification of genetic markers associated with wool quality traits in merino sheep.  

E-Print Network (OSTI)

??A candidate gene approach was used to identify potential genetic markers associated with wool quality traits including mean fibre diameter (MFD), fibre diameter standard deviation… (more)

Itenge-Mweza, Theopoline Omagano

47

Evaluation of LFM-2 Quantitative Precipitation Forecasts  

Science Conference Proceedings (OSTI)

The results of a near real time experiment designed to assess the state of the art of quantitative precipitation forecasting skill of the operational NMC LFM-2 are described. All available LFM-2 quantitative precipitation forecasts were verified ...

Lance F. Bosart

1980-08-01T23:59:59.000Z

48

Quantitative Phase Imaging by Digital Holographic Tomography  

quantitative information about the 3-D position of structures within a sample. ... consistent results ... Measurement Science and Systems Engineering

49

Quantitative Response Measurement of Cell Substrate ...  

Science Conference Proceedings (OSTI)

Quantitative Response Measurement of Cell Substrate Interactions via RT-PCR. Matthew L. Becker, 1 LeeAnn O. Bailey ...

50

Graph sketcher: extending illustration to quantitative graphs  

Science Conference Proceedings (OSTI)

Scientists, engineers, and educators commonly need to make graphs that quickly illustrate quantitative ideas yet are not based on specific data sets. We call these graphs quantitative concept diagrams (QCDs). Existing charting and illustration programs ... Keywords: charting, constraint-based layout, illustration, information visualization, planar map coloring, quantitative concept diagrams, snap-dragging

Robin Stewart; m.c. schraefel

2009-04-01T23:59:59.000Z

51

Multi-Location Evaluation of Agronomic Traits in Maize Hybrids  

E-Print Network (OSTI)

Maize (Zea mays L.) is one of the main crops grown in the United States. Genetic improvement over the last century has seen a shift from using open-pollinated varieties to single cross hybrids. This has resulted in major grain yield gains and improved management methodologies. However, there is still concern about reduced genetic diversity in elite corn germplasm and the potential effects this could have on future maize productivity in the presence of numerous abiotic and biotic pressures. One solution to this issue is the incorporation of exotic germplasm into existing maize improvement programs. This exotic material must be evaluated and characterized because too much or poorly matched exotic material can lead to reduced productivity. The use of multiple environments representative to the target improvement area is the best way to determine the true potential of certain material. The objectives of this research were to: i) estimate the responses of hybrids to aflatoxin and their agronomic performance across a range of environments under inoculation with Aspergillus flavus; ii) identify the hybrids within each group that exhibit the lowest levels of contamination; iii) analyze the relationship between agronomic performance and aflatoxin accumulation; and iv) determine how Genotype x Environment interactions affect these traits. Agronomic data was collected in ten Texas environments in 2005 for hybrids created from yellow, white, and Quality Protein Maize material that was crossed with one of two elite temperate inbred testers, LH195 or LH210. Response to aflatoxin was measured in eight of these environments. U.S. commercial hybrids were used as checks. Significant differences between hybrids were observed at different environments for different traits. Overall the experimental hybrids had lower aflatoxin accumulation than the commercial checks. They also yielded lower and had lower test weights and 1000 kernel weights. However, there were some hybrids that were competitive with the commercial checks for these agronomic traits. The incorporation of this material into established U.S. lines could be beneficial with regards to aflatoxin accumulation and kernel quality, which could ultimately translate to higher yields and crop quality.

McKee, Michael 1982-

2012-12-01T23:59:59.000Z

52

Quantitative Analysis of Station Hydrogen  

NLE Websites -- All DOE Office Websites (Extended Search)

Analysis of Station Analysis of Station Hydrogen * Role of ENAA (Engineering Advancement Association of Japan) - To manage the construction and operation of hydrogen stations in national project, JHFC Project - To act as secretariat of ISO/TC197 (Hydrogen technologies) committee of Japan Kazuo Koseki Chief Secretary of ISO/TC197 of Japan ENAA Yokohama Daikoku Station (Desulfurized Gasoline) Yokohama Asahi Station (Naphtha) Senju Station (LPG) Kawasaki Station (Methanol) Yokohama Asahi Station Naphtha PSA Compressor Storage Tanks Dispenser Reformer Buffer Tank 25 MPa 35 MPa 1073 K 0.8 MPa Inlet : 0.6 MPa Outlet : 40 MPa Vent Stack 40 MPa Result of Quantitative Analysis Concentration. vol.ppm Min.Detect Analysis Impurity Gasoline Naphtha LPG Methanol Conc. Method CO 0.05 0.06 0.02 0.06 0.01 GC-FID

53

SATB1 tethers multiple gene loci to reprogram expression profiledriving breast cancer metastasis  

SciTech Connect

Global changes in gene expression occur during tumor progression, as indicated by expression profiling of metastatic tumors. How this occurs is poorly understood. SATB1 functions as a genome organizer by folding chromatin via tethering multiple genomic loci and recruiting chromatin remodeling enzymes to regulate chromatin structure and expression of a large number of genes. Here we show that SATB1 is expressed at high levels in aggressive breast cancer cells, and is undetectable in non-malignant breast epithelial cells. Importantly, RNAi-mediated removal of SATB1 from highly-aggressive MDA-MB-231 cells altered the expression levels of over 1200 genes, restored breast-like acinar polarity in three-dimensional cultures, and prevented the metastastic phenotype in vivo. Conversely, overexpression of SATB1 in the less-aggressive breast cancer cell line Hs578T altered the gene expression profile and increased metastasis dramatically in vivo. Thus, SATB1 is a global regulator of gene expression in breast cancer cells, directly regulating crucial metastasis-associated genes, including ERRB2 (HER2/NEU), TGF-{beta}1, matrix metalloproteinase 3, and metastasin. The identification of SATB1 as a protein that re-programs chromatin organization and transcription profiles to promote breast cancer metastasis suggests a new model for metastasis and may provide means of therapeutic intervention.

Han, Hye-Jung; Kohwi, Yoshinori; Kohwi-Shigematsu, Terumi

2006-07-13T23:59:59.000Z

54

Quantitative study of oilfield casing damage  

Science Conference Proceedings (OSTI)

Carrying on the analysis to the cause of casing failure based on engineering factors and geological factors, and choosing the improved analytic hierarchy process to have a quantitative study for oilfield of the casing failure, improved the influence ... Keywords: analytical hierarchy process (AHP), casing damage, quantitative analysis

Deng Rui; Zhang Liang; Guo Haimin

2012-09-01T23:59:59.000Z

55

Molecular systematics and phylogeography of the dusky dolphin (Lagenorhynchus obscurus) derived from nuclear and mitochondrial loci  

E-Print Network (OSTI)

This study presents evidence from mitochondrial and nuclear loci that there is genetic divergence among and within geographic populations of Lagenorhynchus obscurus. The effect of seasonal variation on the genetic structure within New Zealand was examined with mitochondrial DNA control region sequences from 4 localities. Analysis of nested haplotype clades indicated genetic fragmentation and at least 1 historical population expansion within New Zealand. AMOVA and Fst values from nuclear and mitochondrial DNA sequences suggested significant divergence between New Zealand, South Africa, Argentina, and Peru. Dispersal via the west-wind drift was not supported by patterns of population structure among regions. Alternatively, these data support reciprocal exchange among all four regions with 100% posterior probability for a root of origin in the Indian/Atlantic Oceans. The degree of divergence between Peru and other regions indicates the isolation of Peruvian stock is temporally correlated with the constriction of Drake�s passage in the Plio-Pleistocene. There is evidence that the Plio-Pliestocene paleoceanography of the Indian and Southern Atlantic Oceans influenced phylogeography with shifts of temperate sea surface temperatures northward ~5º of latitude, disrupting the dispersal corridor between New Zealand and Atlantic populations. A preference for temperate waters along continental shelves is proposed as an explanation for lack of contemporary genetic exchange among regions. This study supports the polyphyly of the genus Lagenorhynchus. North Atlantic species form a monophyletic Lagenorhynchus. In the Southern Hemisphere, L. australis/L. cruciger and L. obliquidens/L. obscurus do not form a monophyletic group. I discuss the taxonomic implications and propose taxonomic revision of the genus based on these results. Measures of character interaction indicate that combined evidence from nuclear and mitochondrial genes provide better phylogenetic resolution among delphinid lineages than any data partition independently, despite some indications of conflict among mitochondrial and nuclear data.

Harlin, April Dawn

2004-12-01T23:59:59.000Z

56

Male 6Female Interaction for a Pre-Copulatory Trait, but Not a Post-Copulatory Trait, among Cosmopolitan Populations of Drosophila melanogaster  

E-Print Network (OSTI)

Sexual coevolution occurs when changes in the phenotype of one sex select for changes in the other sex. We can identify the ‘‘footprint’ ’ of this coevolution by mating males and females from different populations and testing for a male-female genotype interaction for a trait associated with male (or female) performance. Here we mated male Drosophila melanogaster from five different continents with females from their own and different continents to test for a male-female interaction for mating speed, a pre-copulatory trait, and female reproductive investment, a post-copulatory trait. We found a strong malefemale interaction for mating speed, consistent with previous studies using different populations, suggesting that the potential for sexual coevolution for this trait is present in this species. In contrast, we did not detect a male-female interaction for female reproductive investment. Although a male-female interaction for mating speed is compatible with the hypothesis of ongoing sexual coevolution, the nature of our experimental design is unable to exclude alternate explanations. Thus, the evolutionary mechanisms promoting male-female genotype interactions for pre-copulatory mating

Alison Pischedda; Andrew D. Stewart; Monica K. Little

2012-01-01T23:59:59.000Z

57

Report on Solar Water Heating Quantitative Survey  

DOE Green Energy (OSTI)

This report details the results of a quantitative research study undertaken to better understand the marketplace for solar water-heating systems from the perspective of home builders, architects, and home buyers.

Focus Marketing Services

1999-05-06T23:59:59.000Z

58

Report on Solar Pool Heating Quantitative Survey  

DOE Green Energy (OSTI)

This report details the results of a quantitative research study undertaken to better understand the marketplace for solar pool-heating systems from the perspective of residential pool owners.

Synapse Infusion Group, Inc. (Westlake Village, California)

1999-05-06T23:59:59.000Z

59

An Evolutionary Approach in Quantitative Spectroscopy  

Science Conference Proceedings (OSTI)

This paper describes investigations into using evolutionary search for quantitative spectroscopy. Given the spectrum (intensity × frequency) of a sample of material of interest, we would like to be able to infer the make-up of the material in terms ...

Phil Husbands; Pedro Paulo Balbi de Oliveira

1998-11-01T23:59:59.000Z

60

Assistant Professor Quantitative Structural Geology or Geomechanics  

E-Print Network (OSTI)

/tectonics, hydrogeology, stable isotope geochemistry, environmental geology, sedimentology and stratigraphyAssistant Professor Quantitative Structural Geology or Geomechanics The Department of Geology structural geology with interest in the study of fractured reservoirs and geomechanics. The successful

Mohaghegh, Shahab

Note: This page contains sample records for the topic "quantitative trait loci" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


61

Quantitative characterization of vowel formant transitions  

Science Conference Proceedings (OSTI)

This paper presents an acoustic study of vowelformant dynamics and the analysis methods that were developed to carry it out. The main goal of the described study was to bring quantitative

Jim Talley

1992-01-01T23:59:59.000Z

62

Calibration of Probabilistic Quantitative Precipitation Forecasts  

Science Conference Proceedings (OSTI)

From 1 August 1990 to 31 July 1995, the Weather Service Forecast Office in Pittsburgh prepared 6159 probabilistic quantitative precipitation forecasts. Forecasts were made twice a day for 24-h periods beginning at 0000 and 1200 UTC for two river ...

Roman Krzysztofowicz; Ashley A. Sigrest

1999-06-01T23:59:59.000Z

63

Probabilistic Quantitative Precipitation Forecasts for River Basins  

Science Conference Proceedings (OSTI)

A methodology has been formulated to aid a field forecaster in preparing probabilistic quantitative precipitation forecasts (QPFs) for river basins. The format of probabilistic QPF is designed to meet three requirements: (i) it is compatible with ...

Roman Krzysztofowicz; William J. Drzal; Theresa Rossi Drake; James C. Weyman; Louis A. Giordano

1993-12-01T23:59:59.000Z

64

A Bayesian Quantitative Precipitation Nowcast Scheme  

Science Conference Proceedings (OSTI)

Very short-period quantitative precipitation forecast (QPF) or nowcast schemes provide deterministic output that fails to convey explicit measures of the uncertainty in the forecast. Presented here is a forecast methodology based upon a Bayesian ...

Neil I. Fox; Christopher K. Wikle

2005-06-01T23:59:59.000Z

65

Integrated regional assessment: qualitative and quantitative issues  

Science Conference Proceedings (OSTI)

Qualitative and quantitative issues are particularly significant in integrated regional assessment. This chapter examines the terms “qualitative” and “quantitative” separately and in relation to one another, along with a discussion of the degree of interdependence or overlap between the two. Strategies for integrating the two general approaches often produce uneasy compromises. However, integrated regional assessment provides opportunities for strong collaborations in addressing specific problems in specific places.

Malone, Elizabeth L.

2009-11-19T23:59:59.000Z

66

Characterization, Genetic Variation, and Combining Ability of Maize Traits Relevant to the Production of Cellulosic Ethanol  

SciTech Connect

Maize (Zea mays L.) stover has been identified as an important feedstock for the production of cellulosic ethanol. Our objectives were to measure hybrid effect and combining ability patterns of traits related to cellulosic ethanol production, determine if germplasm and mutations used for silage production would also be beneficial for feedstock production, and examine relationships between traits that are relevant to selective breeding. We evaluated grain hybrids, germplasm bred for silage production, brown-midrib hybrids, and a leafy hybrid. Yield and composition traits were measured in four environments. There was a 53% difference in stover yield between commercial grain hybrids that were equivalent for other production-related traits. Silage germplasm may be useful for increasing stover yield and reducing lignin concentration. We found much more variation among hybrids than either in vitro ruminal fermentability or polysaccharide concentration. Correlations between traits were mostly favorable or nonexistent. Our results suggest that utilizing standing genetic variation of maize in breeding programs could substantially increase the amount of biofuels produced from stover per unit area of land.

Lorenz, A. J.; Coors, J. G.; de Leon, N.; Wolfrum, E. J.; Hames, B. R.; Sluiter, A. D.; Weimer, P. J.

2009-01-01T23:59:59.000Z

67

The Cost of Bearing a Sword: Locomotor Costs and Compensations in Relation to a Sexually Selected Trait in Xiphophorus  

E-Print Network (OSTI)

Evaluating performance costs of sexually selected traits.result in a locomotor cost. References Allen, B. J. &Levinton, J. S. (2006). Costs of bearing a sexually selected

Oufiero, Christopher E.

2010-01-01T23:59:59.000Z

68

Canola: Chemistry, Production, Processing and Utilization Chapter 3 Genetic Engineering Approaches for Trait Development in Brassica Oilseed Species  

Science Conference Proceedings (OSTI)

Canola: Chemistry, Production, Processing and Utilization Chapter 3 Genetic Engineering Approaches for Trait Development in Brassica Oilseed Species Processing eChapters Processing AOCS Press Downloadable pdf of

69

Manual for Quantitative Evaluation of the Co-Benefits Approach...  

Open Energy Info (EERE)

Manual for Quantitative Evaluation of the Co-Benefits Approach to Climate Change Jump to: navigation, search Tool Summary Name: Manual for Quantitative Evaluation of the...

70

Category:Quantitative Incentives | Open Energy Information  

Open Energy Info (EERE)

source source History View New Pages Recent Changes All Special Pages Semantic Search/Querying Get Involved Help Apps Datasets Community Login | Sign Up Search Category Edit History Facebook icon Twitter icon » Category:Quantitative Incentives Jump to: navigation, search Category for Quantitative Incentives. Pages in category "Quantitative Incentives" The following 200 pages are in this category, out of 461 total. (previous 200) (next 200) 3 30% Business Tax Credit for Solar (Vermont) A Advanced Energy Tax Credit (Corporate) (New Mexico) Advanced Energy Tax Credit (Personal) (New Mexico) AEP Ohio - Renewable Energy Credit (REC) Purchase Program (Ohio) AEP Ohio - Renewable Energy Technology Program (Ohio) AEP SWEPCO - SMART Source Solar PV Program (Texas) AEP Texas Central Company - SMART Source Solar PV Rebate Program (Texas)

71

Quantitative organic vapor-particle sampler  

DOE Patents (OSTI)

A quantitative organic vapor-particle sampler for sampling semi-volatile organic gases and particulate components. A semi-volatile organic reversible gas sorbent macroreticular resin agglomerates of randomly packed microspheres with the continuous porous structure of particles ranging in size between 0.05-10 .mu.m for use in an integrated diffusion vapor-particle sampler.

Gundel, Lara (Berkeley, CA); Daisey, Joan M. (Walnut Creek, CA); Stevens, Robert K. (Cary, NC)

1998-01-01T23:59:59.000Z

72

Gas quantitative analysis with support vector machine  

Science Conference Proceedings (OSTI)

Gas sensor array is an important part of electronic nose. The gas analysis performance of electronic nose is affected badly by the cross sensitivity of gas sensor array. In order to solve the problem of the cross sensitivity, in this work a new method ... Keywords: electronic nose, gas mixture, quantitative analysis, support vector machine

Liang Xie; Xiaodong Wang

2009-06-01T23:59:59.000Z

73

New multivariate tests for phylogenetic signal and trait correlations applied to ecophysiological phenotypes of  

E-Print Network (OSTI)

to plant growth (basal stem diameter, crown volume, leaf area, relative growth rate); and three measured groups (photosynthesis and plant growth), comprising seven traits in total. 5. Our results demonstrate that even when the number of species in a comparative study is small, resulting in low power for univariate

Payseur, Bret

74

Employing social gaze and speaking activity for automatic determination of the Extraversion trait  

Science Conference Proceedings (OSTI)

In order to predict the Extraversion personality trait, we exploit medium-grained behaviors enacted in group meetings, namely, speaking time and social attention (social gaze). The latter will be further distinguished in to attention given to ... Keywords: personality prediction, speaking activity, support vector machines, visual social gaze

Bruno Lepri; Ramanathan Subramanian; Kyriaki Kalimeri; Jacopo Staiano; Fabio Pianesi; Nicu Sebe

2010-11-01T23:59:59.000Z

75

A comparison of genetic map distance and linkage disequilibrium between 15 polymorphic dinucleotide repeat loci in two populations  

Science Conference Proceedings (OSTI)

Linkage disequilibrium has recently been used to map the diastrophic dysplasia gene in a Finnish sample. One advantage of this method is that the large pedigrees required by some other methods are unnecessary. Another advantage is that linkage disequilibrium mapping capitalizes on the cumulative history of recombination events, rather than those occurring within the sampled individuals. A potential limitation of linkage disequilibrium mapping is that linkage equilibrium is likely to prevail in all but the most isolated populations, e.g., those which have recently experienced founder effects or severe population bottlenecks. In order to test the method`s generality, we examined patterns of linkage disequilibrium between pairs of loci within a known genetic map. Two populations were analyzed. The first population, Navajo Indians (N=45), is an isolate that experienced a severe bottleneck in the 1860`s. The second population, Maryland Caucasians (N=45), is cosmopolitan. We expected the Navajo sample to display more linkage disequilibrium than the Caucasian sample, and possibly that the Navajo disequilibrium pattern would reflect the genetic map. Linkage disequilibrium coefficients were estimated between pairs of alleles at different loci using maximum likelihood. The genetic isolate structure of Navajo Indians is confirmed by the DNA typings. Heterozygosity is lower than in the Caucasians, and fewer different alleles are observed. However, a relationship between genetic map distance and linkage disequilibrium could be discerned in neither the Navajo nor the Maryland samples. Slightly more linkage disequilibrium was observed in the Navajos, but both data sets were characterized by very low disequilibrium levels. We tentatively conclude that linkage disequilibrium mapping with dinucleotide repeats will only be useful with close linkage between markers and diseases, even in very isolated populations.

Urbanek, M.; Goldman, D.; Long, J.C. [Lab. of Neurogenetics, Rockville, MD (United States)

1994-09-01T23:59:59.000Z

76

Methylation status and transcriptional expression of the MHC class I loci in human trophoblast cells from term placenta  

Science Conference Proceedings (OSTI)

Of the various molecular regulatory mechanisms that may be used by human trophoblast cells to down-regulate expression of HLA class I genes, we chose to investigate the methylation of DNA, generally associated with inhibition of transcription. We analyzed the methylation status of different HLA class I loci in villous and extravillous cytotrophoblast cells and in vitro-differentiated syncytiotrophoblast, purified from human term placenta, as well as in the human trophoblast-derived JAR and JEG-3 cell lines. We then compared methylation status and transcriptional activity. An inverse relationship was established between JAR and JEG-3: HLA-A, -B, and -G are methylated and repressed in JAR, whereas in JEG-3, HLA-A is methylated and repressed but HLA-B and -G are partially methylated and transcribed. HLA-E is unmethylated and transcribed in both cell lines. Apart from HLA-E, which is always unmethylated and transcribed, no such relationship exists for the other class I loci in trophoblast cells. Whereas nonclassical HLA-G and classical HLA-A and -B class I genes are undermethylated in both cytotrophoblast and syncytiotrophoblast, they are clearly transcribed in the former but minimally transcribed in the latter subpopulation. Thus, the down-regulation of class I gene expression in the in vitro-differentiated synctiotrophoblast is unlikely to be caused by DNA methylation. Furthermore, there is no detectable expression of any class I molecule at the cell surface of either trophoblast cell subpopulation, suggesting a negative control on translation and/or on the secretory pathway to the plasma membrane. 50 refs., 11 figs., 1 tab.

Guillaudeux, T.; Rodriguez, A.M.; Girr, M. [University Hospital Center Purpan, Toulouse (France)] [and others

1995-04-01T23:59:59.000Z

77

Strong quantitative benchmarking of quantum optical devices  

E-Print Network (OSTI)

Quantum communication devices, such as quantum repeaters, quantum memories, or quantum channels, are unavoidably exposed to imperfections. However, the presence of imperfections can be tolerated, as long as we can verify such devices retain their quantum advantages. Benchmarks based on witnessing entanglement have proven useful for verifying the true quantum nature of these devices. The next challenge is to characterize how strongly a device is within the quantum domain. We present a method, based on entanglement measures and rigorous state truncation, which allows us to characterize the degree of quantumness of optical devices. This method serves as a quantitative extension to a large class of previously-known quantum benchmarks, requiring no additional information beyond what is already used for the non-quantitative benchmarks.

Nathan Killoran; Norbert Lütkenhaus

2011-02-16T23:59:59.000Z

78

Quantitative determination of atmospheric hydroperoxyl radical  

SciTech Connect

A method for the quantitative determination of atmospheric hydroperoxyl radical comprising: (a) contacting a liquid phase atmospheric sample with a chemiluminescent compound which luminesces on contact with hydroperoxyl radical; (b) determining luminescence intensity from the liquid phase atmospheric sample; and (c) comparing said luminescence intensity from the liquid phase atmospheric sample to a standard luminescence intensity for hydroperoxyl radical. An apparatus for automating the method is also included.

Springston, Stephen R. (Upton, NY); Lloyd, Judith (Westbury, NY); Zheng, Jun (Stony Brook, NY)

2007-10-23T23:59:59.000Z

79

Quantitative resilience analysis through control design.  

Science Conference Proceedings (OSTI)

Critical infrastructure resilience has become a national priority for the U. S. Department of Homeland Security. System resilience has been studied for several decades in many different disciplines, but no standards or unifying methods exist for critical infrastructure resilience analysis. Few quantitative resilience methods exist, and those existing approaches tend to be rather simplistic and, hence, not capable of sufficiently assessing all aspects of critical infrastructure resilience. This report documents the results of a late-start Laboratory Directed Research and Development (LDRD) project that investigated the development of quantitative resilience through application of control design methods. Specifically, we conducted a survey of infrastructure models to assess what types of control design might be applicable for critical infrastructure resilience assessment. As a result of this survey, we developed a decision process that directs the resilience analyst to the control method that is most likely applicable to the system under consideration. Furthermore, we developed optimal control strategies for two sets of representative infrastructure systems to demonstrate how control methods could be used to assess the resilience of the systems to catastrophic disruptions. We present recommendations for future work to continue the development of quantitative resilience analysis methods.

Sunderland, Daniel; Vugrin, Eric D.; Camphouse, Russell Chris (Sandia National Laboratories, Carlsbad, NM)

2009-09-01T23:59:59.000Z

80

Strong quantitative benchmarking of quantum optical devices  

Science Conference Proceedings (OSTI)

Quantum communication devices, such as quantum repeaters, quantum memories, or quantum channels, are unavoidably exposed to imperfections. However, the presence of imperfections can be tolerated, as long as we can verify that such devices retain their quantum advantages. Benchmarks based on witnessing entanglement have proven useful for verifying the true quantum nature of these devices. The next challenge is to characterize how strongly a device is within the quantum domain. We present a method, based on entanglement measures and rigorous state truncation, which allows us to characterize the degree of quantumness of optical devices. This method serves as a quantitative extension to a large class of previously known quantum benchmarks, requiring no additional information beyond what is already used for the nonquantitative benchmarks.

Killoran, N.; Luetkenhaus, N. [Institute for Quantum Computing and Department of Physics and Astronomy, University of Waterloo, Waterloo, N2L 3G1 (Canada)

2011-05-15T23:59:59.000Z

Note: This page contains sample records for the topic "quantitative trait loci" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


81

Quantitative Spectroscopy of BA-type Supergiants  

E-Print Network (OSTI)

Luminous BA-SGs allow topics ranging from NLTE physics and the evolution of massive stars to the chemical evolution of galaxies and cosmology to be addressed. A hybrid NLTE technique for the quantitative spectroscopy of BA-SGs is discussed. Thorough tests and first applications of the spectrum synthesis method are presented for four bright Galactic objects. Stellar parameters are derived from spectroscopic indicators. The internal accuracy of the method allows the 1sigma-uncertainties to be reduced to reduce random errors and remove systematic trends in the analysis. Inappropriate LTE analyses tend to systematically underestimate iron group abundances and overestimate the light and alpha-process element abundances by up to factors of 2-3 on the mean. Contrary to common assumptions, significant NLTE abundance correction...

Przybilla, N; Becker, S R; Kudritzki, R P

2005-01-01T23:59:59.000Z

82

QTL and Candidate Genes for Growth Traits in Pinus Taeda L  

DOE Green Energy (OSTI)

The reason for the project is to find the genetic factors which control growth at ages closer to commercial harvest (also known as QTL detection). To date, efforts to find genetic factors which control growth have been limited to seedlings. Because tree breeders want to find molecular markers which are linked to traits of direct economic value, finding linkage to factors controlling older-tree growth is more critical than seedling growth. Our current research interest includes both absolute height at ages 10-13 years but also growth trajectory or the rate of growth from seedling to half-rotation.

Claire G. Williams

2002-10-01T23:59:59.000Z

83

Quantitative Determination of Twin Volume Fraction in TWIP Steels ...  

Science Conference Proceedings (OSTI)

By using a newly developed low-accelerating-voltage high-resolution EBSD technique, the nanotwin volume fraction can be quantitatively determined, leading ...

84

Deuterium and Tritium Applications to the Quantitative Study ... - TMS  

Science Conference Proceedings (OSTI)

Sep 1, 1994 ... Deuterium and Tritium Applications to the Quantitative Study of Hydrogen Local Concentration Metals and Related Embrittlement by J. Chene ...

85

New Tool Quantitatively Maps Minority-Carrier Lifetime of Multicrystal...  

NLE Websites -- All DOE Office Websites (Extended Search)

and Integration Laboratory (PDIL) to generate quantitative minority-carrier lifetime maps of multicrystalline silicon (mc-Si) bricks. This feat has been accomplished by using...

86

New NIST-Traceable Standard for Accuracy in Quantitative ...  

Science Conference Proceedings (OSTI)

... NIST-Traceable Standard for Accuracy in Quantitative Nuclear Medicine Imaging ... As the technology has matured, PET is increasingly being used a ...

2010-10-05T23:59:59.000Z

87

10 Questions for a Quantitative Geneticist: Wellington Muchero...  

NLE Websites -- All DOE Office Websites (Extended Search)

Geneticist: Wellington Muchero Wellington Muchero is a quantitative geneticist at the Bioenergy Science Center in Oak Ridge, Tennessee. Photo by Jason Richards, Oak Ridge National...

88

Quantitative infrared analysis of hydrogen fluoride  

SciTech Connect

This work was performed at the Portsmouth Gaseous Diffusion Plant where hydrogen fluoride is produced upon the hydrolysis of UF{sub 6}. This poses a problem for in this setting and a method for determining the mole percent concentration was desired. HF has been considered to be a non-ideal gas for many years. D. F. Smith utilized complex equations in his HF studies in the 1950s. We have evaluated HF behavior as a function of pressure from three different perspectives. (1) Absorbance at 3877 cm{sup -1} as a function of pressure for 100% HF. (2) Absorbance at 3877 cm{sup -1} as a function of increasing partial pressure HF. Total pressure = 300 mm HgA maintained with nitrogen. (3) Absorbance at 3877 cm{sup -1} for constant partial pressure HF. Total pressure is increased to greater than 800 mm HgA with nitrogen. These experiments have shown that at partial pressures up to 35mm HgA, HIF follows the ideal gas law. The absorbance at 3877 cm{sup -1} can be quantitatively analyzed via infrared methods.

Manuta, D.M.

1997-04-01T23:59:59.000Z

89

Quantitative Modeling of Cerenkov Light Production Efficiency from Medical Radionuclides  

E-Print Network (OSTI)

Quantitative Modeling of Cerenkov Light Production Efficiency from Medical Radionuclides Bradley J There has been recent and growing interest in applying Cerenkov radiation (CR) for biological applications) Quantitative Modeling of Cerenkov Light Production Efficiency from Medical Radionuclides. PLoS ONE 7(2): e31402

Hielscher, Andreas

90

Method of quantitating dsDNA  

DOE Patents (OSTI)

A method for quantitating dsDNA in an aqueous sample solution containing an unknown amount of dsDNA. A first aqueous test solution containing a known amount of a fluorescent dye-dsDNA complex and at least one fluorescence-attenutating contaminant is prepared. The fluorescence intensity of the test solution is measured. The first test solution is diluted by a known amount to provide a second test solution having a known concentration of dsDNA. The fluorescence intensity of the second test solution is measured. Additional diluted test solutions are similarly prepared until a sufficiently dilute test solution having a known amount of dsDNA is prepared that has a fluorescence intensity that is not attenuated upon further dilution. The value of the maximum absorbance of this solution between 200-900 nanometers (nm), referred to herein as the threshold absorbance, is measured. A sample solution having an unknown amount of dsDNA and an absorbance identical to that of the sufficiently dilute test solution at the same chosen wavelength is prepared. Dye is then added to the sample solution to form the fluorescent dye-dsDNA-complex, after which the fluorescence intensity of the sample solution is measured and the quantity of dsDNA in the sample solution is determined. Once the threshold absorbance of a sample solution obtained from a particular environment has been determined, any similarly prepared sample solution taken from a similar environment and having the same value for the threshold absorbance can be quantified for dsDNA by adding a large excess of dye to the sample solution and measuring its fluorescence intensity.

Stark, Peter C. (Los Alamos, NM); Kuske, Cheryl R. (Los Alamos, NM); Mullen, Kenneth I. (Los Alamos, NM)

2002-01-01T23:59:59.000Z

91

Rapid quantitative assay for chloramphenicol acetyltransferase  

SciTech Connect

Measuring the expression of exogenous genetic material in mammalian cells is commonly done by fusing the DNA of interest to a gene encoding an easily-detected enzyme. Chloramphenicol acetyltransferase(CAT) is a convenient marker because it is not normally found in eukaryotes. CAT activity has usually been detected using a thin-layer chromatographic separation followed by autoradiography. An organic solvent extraction-based method for CAT detection has also been described, as well as a procedure utilizing HPLC analysis. Building on the extraction technique, they developed a rapid sensitive kinetic method for measuring CAT activity in cell homogenates. The method exploits the differential organic solubility of the substrate ((/sup 3/H) or (/sup 14/C)acetyl CoA) and the product (labeled acetylchloramphenicol). The assay is a simple one-vial, two-phase procedure and requires no tedious manipulations after the initial setup. Briefly, a 0.25 ml reaction with 100mM Tris-HCL, 1mM chloramphenicol, 0.1mM (/sup 14/C)acetyl CoA and variable amounts of cell homogenate is pipetted into a miniscintillation vial, overlaid with 5 ml of a water-immiscible fluor, and incubated at 37/sup 0/C. At suitable intervals the vial is counted and the CAT level is quantitatively determined as the rate of increase in counts/min of the labeled product as it diffuses into the fluor phase, compared to a standard curve. When used to measure CAT in transfected Balb 3T3 cells the method correlated well with the other techniques.

Neumann, J.R.; Morency, C.A.; Russian, K.O.

1987-05-01T23:59:59.000Z

92

10 Questions for a Quantitative Geneticist: Wellington Muchero | Department  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Quantitative Geneticist: Wellington Muchero Quantitative Geneticist: Wellington Muchero 10 Questions for a Quantitative Geneticist: Wellington Muchero July 1, 2013 - 11:15am Addthis Wellington Muchero is a quantitative geneticist at the Bioenergy Science Center in Oak Ridge, Tennessee. | Photo by Jason Richards, Oak Ridge National Laboratory. Wellington Muchero is a quantitative geneticist at the Bioenergy Science Center in Oak Ridge, Tennessee. | Photo by Jason Richards, Oak Ridge National Laboratory. On what led him to a career in science, Wellington Muchero says, "As soon as I got a part-time job in a plant molecular biology lab as a college student, I realized there was no turning back." | Photo courtesy of Wellington Muchero. On what led him to a career in science, Wellington Muchero says, "As soon

93

Multiple prey traits, multiple predators: keys to understanding complex species interactions  

E-Print Network (OSTI)

Species interactions generate both natural selection and ecological community structure. Among the more interesting species interactions are those that create adaptive tradeoffs-where phenotypes conferring improved performance in interactions with one species decrease performance with another. Such tradeoffs create divergent natural selection and favor the evolution of strategies such as phenotypic plasticity. Functional tradeoffs may also provide little "enemy-free space" for a focal species in complex communities, resulting in emergent ecological impacts. Emergent community properties arise when community patterns are not predicted based on additive knowledge of pairwise interactions. These emergent impacts typically result from indirect effects, where interactions between two species depend on intermediary species. In this thesis, I examined constraints on the evolution of phenotypic plasticity and addressed its potential significance in community dynamics. I further reviewed concepts and issues related to linking functional and community studies to elucidate mechanisms underlying community structure. I proposed an integrative approach to the subject, emphasizing four major areas of promise, by combining perspectives of ecology and evolution. Freshwater physid snails induce defensive phenotypes in the presence of specialized molluscivorous sunfish. While predator-induced shells reduce predation from shell-crushing fish, I examined whether non-predatory fish induced unnecessary responses. I raised freshwater snails, Physella virgata, with either molluscivorous or non-molluscivorous sunfish species. Regardless of the predator class with which they were raised, snails exhibited two induced responses: reduced growth, and development of rotund shells. Although induced responses are adaptive in the presence of molluscivorous species, responding unnecessarily to non-molluscivores is maladaptive. Both growth reduction and rotund shells entail substantial costs without compensatory benefits in the absence of predatory fish. A pluralistic approach to studying ecological interactions shaping community dynamics should prove profitable in revealing details of complex interactions. I primarily illustrate these principles with case studies involving predation ecology in the freshwater snail-fish-crayfish model system. The system illustrates how predator impacts on prey are mediated by multiple prey traits, correlations between traits, functional tradeoffs in predator defense, interactions between predators, and interactions with other community members. These case studies demonstrate the importance of a multiple-trait and multiple-environment perspective in functional ecological studies.

Langerhans, Randall Brian

2002-01-01T23:59:59.000Z

94

Low Dose Radiation Research Program: Do Heritable Differences in an  

NLE Websites -- All DOE Office Websites (Extended Search)

Do Heritable Differences in an Individual's Immune System Predict Do Heritable Differences in an Individual's Immune System Predict Differential Sensitivity to Low Dose Radiation Exposure? Quantitative trait loci (QTL) mapping Enlarge Image Quantitative trait loci (QTL) mapping identifies two strong candidate genes, Ptprk (Chr 10) and Acp1 (Chr 12) that are linked to genetic variation in the relative abundance of peripheral Th and Tc cells, two cell populations that are sensitive to radiation exposure at low doses. Expression of each gene is significantly altered by exposure to low dose radiation in vivo. Genome-wide scans for the ratio of %CD4+ (Th) to %CD8+ (Tc) lymphocytes were performed using genenetwork.org. The solid horizontal line represents genome-wide significance at P < 0.05, based on 1,000 permutations. LOD indicates logarithm of odds scores.

95

Phenotypic Data Collection and Sample Preparation for Genomics of Wood Formation and Cellulosic Biomass Traits in Sunflower: Ames, IA location.  

Science Conference Proceedings (OSTI)

Three fields were planted in Ames in 2010, two association mapping fields, N3 and A, and a recombinant inbred line field, N13. Phenotype data and images were transferred to UGA to support genetic and genomic analyses of woody biomass-related traits.

Marek, Laura F.

2011-06-17T23:59:59.000Z

96

Quantitative room-temperature mineralization of airborne formaldehyde using  

NLE Websites -- All DOE Office Websites (Extended Search)

Quantitative room-temperature mineralization of airborne formaldehyde using Quantitative room-temperature mineralization of airborne formaldehyde using manganese oxide catalysts Title Quantitative room-temperature mineralization of airborne formaldehyde using manganese oxide catalysts Publication Type Journal Article Year of Publication 2011 Authors Sidheswaran, Meera A., Hugo Destaillats, Douglas P. Sullivan, Joern Larsen, and William J. Fisk Journal Applied Catalysis B - Environmental Issue 107 Pagination 34-41 Date Published 2011 Keywords commercial building ventilation & indoor environmental quality group, commercial building ventilation and indoor environmental quality group, energy analysis and environmental impacts department, indoor environment department, indoor environment group DOI 10.1016/j.apcatb.2011.06.032 Attachment Size

97

Quantitative research and issues of political sensitivity in rural China  

E-Print Network (OSTI)

Political sensitivity is always a challenge for the scholar doing fieldwork in nondemocratic and transitional systems, especially when doing surveys and quantitative research. Not only are more research topics likely to ...

Tsai, Lily L.

98

Quantitative Precipitation Forecast Techniques for Use in Hydrologic Forecasting  

Science Conference Proceedings (OSTI)

Quantitative hydrologic forecasting usually requires knowledge of the spatial and temporal distribution of precipitation. First, it is important to accurately measure the precipitation falling over a particular watershed of interest. Second, ...

Konstantine P. Georgakakos; Michael D. Hudlow

1984-11-01T23:59:59.000Z

99

The WGNE Assessment of Short-term Quantitative Precipitation Forecasts  

Science Conference Proceedings (OSTI)

Twenty-four-hour and 48-h quantitative precipitation forecasts (QPFs) from 11 operational numerical weather prediction models have been verified for a 4-yr period against rain gauge observations over the United States, Germany, and Australia to ...

Elizabeth E. Ebert; Ulrich Damrath; Werner Wergen; Michael E. Baldwin

2003-04-01T23:59:59.000Z

100

Probabilistic Quantitative Precipitation Forecast for Flood Prediction: An Application  

Science Conference Proceedings (OSTI)

This paper outlines a methodology to produce probabilistic quantitative precipitation forecasts by means of a dedicated uncertainty processor for weather model output. The uncertainty processor is developed as a component of a Bayesian ...

P. Reggiani; A. H. Weerts

2008-02-01T23:59:59.000Z

Note: This page contains sample records for the topic "quantitative trait loci" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


101

Quantitation of Glycidyl Esters via Stable Isotope Dilution Analysis  

Science Conference Proceedings (OSTI)

Quantitation of Glycidyl Esters via Stable Isotope Dilution Analysis Michael Granvogl and Peter Schieberle Technical University of Munich, Chair for Food Chemistry and German Research Centre for Food Chemistry, Lise-Meitner-Str. 34, Freising, Germ

102

Geothermal Reconnaissance From Quantitative Analysis Of Thermal Infrared  

Open Energy Info (EERE)

Geothermal Reconnaissance From Quantitative Analysis Of Thermal Infrared Geothermal Reconnaissance From Quantitative Analysis Of Thermal Infrared Imagery Jump to: navigation, search GEOTHERMAL ENERGYGeothermal Home Reference Material: Geothermal Reconnaissance From Quantitative Analysis Of Thermal Infrared Imagery Details Activities (1) Areas (1) Regions (0) Abstract: Unavailable Author(s): K. Watson Published: Proceedings of the ninth international symposium on remote sensing of environment, April 15-19, p. 1919-1932., 1974 Document Number: Unavailable DOI: Unavailable Thermal And-Or Near Infrared At Raft River Geothermal Area (1974-1976) Raft River Geothermal Area Retrieved from "http://en.openei.org/w/index.php?title=Geothermal_Reconnaissance_From_Quantitative_Analysis_Of_Thermal_Infrared_Imagery&oldid=387504" Category:

103

Evaluation of ultrasound and other sources of information to predict beef carcass traits and final carcass value  

E-Print Network (OSTI)

Purebred Beefmaster steers (n = 160) from five owners were fed at a commercial feedlot in South Texas beginning in November of 2004; 68 steers possessed pedigree information. Beginning in mid-November, steers were individually weighed and evaluated for ultrasound body composition at 56-d intervals by a certified technician. Feeder calf frame (FRM) and muscle (MUS) scores were assigned at initial ultrasound evaluation. Steers were fed and marketed through a lean-based, branded beef program and were harvested in two groups in May and June of 2005 at a commercial beef plant. Analyses were conducted to investigate the ability to predict carcass traits from the different sources of information available on these cattle. Evaluation of carcass traits were investigated using four sets of independent variables referred to as sources A, B, C, or D and ultrasound scan session (1 Â? 4). An analysis included initial weight at first scan session (IWT), FRM and MUS as independent variables through GLM procedures. B analyses utilized ultrasound measures of the longissimus area, intramuscular fat, fat thickness, rump fat, and gluteus medius depth along with IWT as independent variables. Multiple regression was performed on each carcass trait using IWT and ultrasound traits at each scan session. MallowÂ?s CP was used to select a model that best described each carcass trait. C analyses (GLM) utilized variables from A and B analyses combined plus ranch. D analyses (GLM) included variables from C analyses plus sire nested within ranch. Respective R-square values (scan 1 Â? 4) for marbling score were .02, .04, .05, and .10 using A information, .14, .17, .42, and .54, using B information, .35, .35, .47, and .55 using C information, and .56, .59, .65, and .76 using D information. R-square values ranged from .34 to .86 for carcass weight, .11 to .77 for fat thickness, .06 to .82 for ribeye area, and .10 to .81 for yield grade. Ultrasound data obtained closer to harvest and increasing amount of data related to genetic and management background showed increased R-square values, but may be best utilized in conjunction with one another to predict carcass traits and final carcass value.

Dean, Dustin Tyler

2003-05-01T23:59:59.000Z

104

Populus trichocarpa cell wall chemistry and ultrastructure trait variation, genetic control and genetic correlations  

NLE Websites -- All DOE Office Websites (Extended Search)

Populus Populus trichocarpa cell wall chemistry and ultrastructure trait variation, genetic control and genetic correlations Ilga Porth 1 *, Jaroslav Kla ´ ps ˇte ˇ 2 *, Oleksandr Skyba 1 , Ben S. K. Lai 1 , Armando Geraldes 3 , Wellington Muchero 4 , Gerald A. Tuskan 4 , Carl J. Douglas 3 , Yousry A. El-Kassaby 2 and Shawn D. Mansfield 1 1 Department of Wood Science, Faculty of Forestry, University of British Columbia, Vancouver, BC, V6T 1Z4, Canada; 2 Department of Forest Sciences, Faculty of Forestry, University of British Columbia, Vancouver, BC, V6T 1Z4, Canada; 3 Department of Botany, University of British Columbia, Vancouver, BC, V6T 1Z4, Canada; 4 BioSciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, 37831, USA Authors for correspondence: Shawn D. Mansfield Tel: +1 604 822 0196 Email: shawn.mansfield@ubc.ca Yousry A. El-Kassaby Tel: +1 604 822 1821 Email: y.el-kassaby@ubc.ca

105

Designing Soybeans for the 21st Century MarketsChapter 9 Implementing a Uniform Process for Measurement of Soybean Quality Traits  

Science Conference Proceedings (OSTI)

Designing Soybeans for the 21st Century Markets Chapter 9 Implementing a Uniform Process for Measurement of Soybean Quality Traits Biofuels and Bioproducts and Biodiesel Food Science Health Nutrition Biochemistry Processing Biofuels -

106

Designing Soybeans for the 21st Century MarketsChapter 16 Accelerated Yield Technology™: A Platform for Marker Assisted Selection of Simple and Complex Traits  

Science Conference Proceedings (OSTI)

Designing Soybeans for the 21st Century Markets Chapter 16 Accelerated Yield Technology™: A Platform for Marker Assisted Selection of Simple and Complex Traits Biofuels - Bioproducts eChapters Food Science & Technology Health - Nutrition

107

Designing Soybeans for the 21st Century MarketsChapter 5 Genes and Alleles for Quality Traits on the Soybean Genetic/Physical Map  

Science Conference Proceedings (OSTI)

Designing Soybeans for the 21st Century Markets Chapter 5 Genes and Alleles for Quality Traits on the Soybean Genetic/Physical Map Biofuels and Bioproducts and Biodiesel Food Science Health Nutrition Biochemistry Processing Biofuels -

108

ARM - Evaluation Product - Quantitative Precipitation Estimates (QPE) from  

NLE Websites -- All DOE Office Websites (Extended Search)

ProductsQuantitative Precipitation Estimates (QPE) ProductsQuantitative Precipitation Estimates (QPE) from the CSAPR Comments? We would love to hear from you! Send us a note below or call us at 1-888-ARM-DATA. Send Evaluation Product : Quantitative Precipitation Estimates (QPE) from the CSAPR Site(s) SGP TWP General Description Precipitation rates from cloud systems can give a fundamental insight into the processes occurring in-cloud. While rain gauges and disdrometers can give information at a single point, remote sensors such as radars can provide rainfall information over a defined area. The QPE value-added product (VAP) takes the Corrected Moments in Antenna Coordinates VAP and maps the Rain_rate_A field onto a Cartesian grid at the surface. This field is the rain rate as determined using the specific attenuation (A, dBZ/km) due to two-way liquid attenuation after Ryzhkov et

109

Quantitative interpretation of tracer test data | Open Energy Information  

Open Energy Info (EERE)

Quantitative interpretation of tracer test data Quantitative interpretation of tracer test data Jump to: navigation, search OpenEI Reference LibraryAdd to library Conference Paper: Quantitative interpretation of tracer test data Abstract Geothermal reinjection is an important part of sustainable management of geothermal resources. Reinjection started out as a method of waste-water disposal, but is now also being used to counteract pressure draw-down and to extract more thermal energy from reservoir rocks. The possible cooling of production wells, or thermal breakthrough, is one of the main disadvantages associated with injection. To minimize this danger while maintaining the benefit from reinjection requires careful testing and research. Tracer testing, which is used to study flow-paths and quantify fluid-flow in hydrological systems, is probably the most important tool for

110

Method for quantitative assessment of nuclear safety computer codes. [PWR  

SciTech Connect

A procedure has been developed for the quantitative assessment of nuclear safety computer codes and tested by comparison of RELAP4/MOD6 predictions with results from two Semiscale tests. This paper describes the developed procedure, the application of the procedure to the Semiscale tests, and the results obtained from the comparison.

Dearien, J.A.; Davis, C.B.; Matthews, L.J.

1979-01-01T23:59:59.000Z

111

Real time quantitative elastography using supersonic shear wave imaging  

Science Conference Proceedings (OSTI)

Supersonic Shear Imaging (SSI) is a quantitative stiffness imaging technique based on the combination of a radiation force induced in tissue by an ultrasonic beam and ultrafast ultrasound imaging sequence (up to more than 10000 frames per second) catching ... Keywords: cancer, diagnosis, elastography, ultrafast imaging, ultrasound

Mickael Tanter; Mathieu Pernot; Gabriel Montaldo; Jean-Luc Gennisson; Eric Bavu; Emilie Macé; Thu-Mai Nguyen; Mathieu Couade; Mathias Fink

2010-04-01T23:59:59.000Z

112

QUANTITATIVE METALLOGRAPHY OF PLUTONIUM USING POINT-COUNT TECHNIQUES  

SciTech Connect

A point-counter was designed and adapted for use on a ausch and Lomb Balphot Metallograph. The results of quantitative metallography performed on materials with two or more phases are given and some of the results are compared with x-ray analysis. (auth)

Greeson, R.L.

1964-01-01T23:59:59.000Z

113

Low Dose Radiation Research Program: Quantitative Analysis of Connexin  

NLE Websites -- All DOE Office Websites (Extended Search)

Quantitative Analysis of Connexin Expression in Cultured Colonies Quantitative Analysis of Connexin Expression in Cultured Colonies Authors: B. Parvin, Q. Yang, R. L. Henshall-Powell and M.H. Barcellos Hoff We are studying the effects of ionizing radiation on the signaling between human mammary epithelial cells and the extracellular microenvironment. To do so we use an assay based on the ability of the cells to organize into three-dimensional acini when embedded into an extracellular matrix. Although tumorigenic and non-tumorigenic mammary epithelial cells are nearly indistinguishable when cultured as monolayers, their biological character readily diverge when tissue-specific morphogenesis is analyzed. Non-malignant human mammary epithelial cells (HMEC) cultured within a reconstituted basement membrane organize into acinar-like structures with

114

Review of progress in quantitative NDE. [Nondestructive Evaluation (NDE)  

Science Conference Proceedings (OSTI)

This booklet is composed of abstracts from papers submitted at a meeting on quantitative NDE. A multitude of topics are discussed including analysis of composite materials, NMR uses, x-ray instruments and techniques, manufacturing uses, neural networks, eddy currents, stress measurements, magnetic materials, adhesive bonds, signal processing, NDE of mechanical structures, tomography,defect sizing, NDE of plastics and ceramics, new techniques, optical and electromagnetic techniques, and nonlinear techniques. (GHH)

Not Available

1991-01-01T23:59:59.000Z

115

A Quantitative Tool for Producing DNA-Based Diagnostic Arrays  

SciTech Connect

The purpose of this project was to develop a precise, quantitative method to analyze oligodeoxynucleotides (ODNs) on an array to enable a systematic approach to quality control issues affecting DNA microarrays. Two types of ODN's were tested; ODN's formed by photolithography and ODN's printed onto microarrays. Initial work in Phase I, performed in conjunction with Affymetrix, Inc. who has a patent on a photolithographic in situ technique for creating DNA arrays, was very promising but did seem to indicate that the atomization process was not complete. Soon after Phase II work was under way, Affymetrix had further developed fluorescent methods and indicated they were no longer interested in our resonance ionization technique. This was communicated to the program manager and it was decided that the project would continue and be focused on printed ODNs. The method being tested is called SIRIS, Sputter-Initiated Resonance Ionization Spectroscopy. SIRIS has been shown to be a highly sensitive, selective, and quantitative tool for atomic species. This project was aimed at determining if an ODN could be labeled in such a way that SIRIS could be used to measure the label and thus provide quantitative measurements of the ODN on an array. One of the largest problems in this study has been developing a method that allows us to know the amount of an ODN on a surface independent of the SIRIS measurement. Even though we could accurately determine the amount of ODN deposited on a surface, the amount that actually attached to the surface is very difficult to measure (hence the need for a quantitative tool). A double-labeling procedure was developed in which 33P and Pt were both used to label ODNs. The radioactive 33P could be measured by a proportional counter that maps the counts in one dimension. This gave a good measurement of the amount of ODN remaining on a surface after immobilization and washing. A second label, Pt, was attached to guanine nucleotides in the ODN. Studies were conducted using this technique and comparing the results of the radioactive label vs SIRIS measurements of Pt as a function of ODN length and distance of the Pt label from the attachment end. The SIRIS signal was not proportional to the amount of oligo attached to the surface as determined by the decay of the 33P label. We intentionally tested conditions under which one might expect the atomization efficiency to change and we believe this is the problem. Different lengths of oligos, and different placement of the label in the oligo affected the final signal. This obviously makes use of SIRIS as a quantitative tool for oligonucleotides problematic except under highly controlled situations.

Tom J. Whitaker

2008-07-11T23:59:59.000Z

116

Validation of Quantitative Method for Glycidol Fatty Acid Esters in Edible Oils  

Science Conference Proceedings (OSTI)

Validation of Quantitative Method for Glycidol Fatty Acid Esters (GEs) in Edible Oils Hiroki Shiro, Naoki Kondo and Yoshinori Masukawa

117

Quantitative mobility spectrum analysis (QMSA) for hall characterization of electrons and holes in anisotropic bands  

Science Conference Proceedings (OSTI)

Keywords: Bi films, Bi/CdTe superlattices, Si, anisotropic bands, magnetotransport, quantitative mobility spectrum analysis (QMSA), thermoelectric properties

I. Vurgaftman; J. R. Meyer; C. A. Hoffman; S. Cho; J. B. Ketterson; L. Faraone; J. Antoszewski; J. R. Lindemuth

1999-05-01T23:59:59.000Z

118

Nuclear medicine and imaging research (instrumentation and quantitative methods of evaluation)  

SciTech Connect

This document is the annual progress report for project entitled 'Instrumentation and Quantitative Methods of Evaluation.' Progress is reported in separate sections individually abstracted and indexed for the database. Subject areas reported include theoretical studies of imaging systems and methods, hardware developments, quantitative methods of evaluation, and knowledge transfer: education in quantitative nuclear medicine imaging.

Beck, R.N.; Cooper, M.; Chen, C.T.

1992-07-01T23:59:59.000Z

119

Integration of hydrothermal-energy economics: related quantitative studies  

DOE Green Energy (OSTI)

A comparison of ten models for computing the cost of hydrothermal energy is presented. This comparison involved a detailed examination of a number of technical and economic parameters of the various quantitative models with the objective of identifying the most important parameters in the context of accurate estimates of cost of hydrothermal energy. Important features of various models, such as focus of study, applications, marked sectors covered, methodology, input data requirements, and output are compared in the document. A detailed sensitivity analysis of all the important engineering and economic parameters is carried out to determine the effect of non-consideration of individual parameters.

Not Available

1982-08-01T23:59:59.000Z

120

QuantUM: Quantitative Safety Analysis of UML Models  

E-Print Network (OSTI)

When developing a safety-critical system it is essential to obtain an assessment of different design alternatives. In particular, an early safety assessment of the architectural design of a system is desirable. In spite of the plethora of available formal quantitative analysis methods it is still difficult for software and system architects to integrate these techniques into their every day work. This is mainly due to the lack of methods that can be directly applied to architecture level models, for instance given as UML diagrams. Also, it is necessary that the description methods used do not require a profound knowledge of formal methods. Our approach bridges this gap and improves the integration of quantitative safety analysis methods into the development process. All inputs of the analysis are specified at the level of a UML model. This model is then automatically translated into the analysis model, and the results of the analysis are consequently represented on the level of the UML model. Thus the analysi...

Leitner-Fischer, Florian; 10.4204/EPTCS.57.2

2011-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "quantitative trait loci" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


121

N reactor individual risk comparison to quantitative nuclear safety goals  

Science Conference Proceedings (OSTI)

A full-scope level III probabilistic risk assessment (PRA) has been completed for N reactor, a US Department of Energy (DOE) production reactor located on the Hanford Reservation in the state of Washington. Sandia National Laboratories (SNL) provided the technical leadership for this work, using the state-of-the-art NUREG-1150 methodology developed for the US Nuclear Regulatory Commission (NRC). The main objectives of this effort were to assess the risks to the public and to the on-site workers posed by the operation of N reactor, to identify changes to the plant that could reduce the overall risk, and to compare those risks to the proposed NRC and DOE quantitative safety goals. This paper presents the methodology adopted by Westinghouse Hanford Company (WHC) and SNL for individual health risk evaluation, its results, and a comparison to the NRC safety objectives and the DOE nuclear safety guidelines. The N reactor results, are also compared with the five NUREG-1150 nuclear plants. Only internal events are compared here because external events are not yet reported in the current draft NUREG-1150. This is the first full-scope level III PRA study with a detailed quantitative safety goal comparison performed for DOE production reactors.

Wang, O.S.; Rainey, T.E.; Zentner, M.D.

1990-01-01T23:59:59.000Z

122

Quantitative training system assessments using General Systems Performance Theory  

E-Print Network (OSTI)

The use of computers for imparting education and training is rapidly gaining widespread acceptance. There is considerable evidence in literature to show that computer-based training (CBT) can lower training costs and shorten the time taken to complete training. Although considerable work has been done in the area of development of computer-based training systems, there has been little work done in the domain of assessing the effectiveness of using computer-based methods for the purposes of training. Furthermore, performance evaluations of CBT systems to date have been performed using ad-hoc, context-specific methods. There is thus a need to provide a uniform basis for performance assessments of computer-based training systems. This thesis presents a quantitative approach to the problem of performance assessments of CBT systems, using a theoretical framework known as General Systems Performance Theory. We believe the approach presented in this thesis can be used to provide a quantitative characterization of the performance of any training system in any training domain. The thesis also demonstrates the proposed approach by applying it to evaluate the performance of a set of training systems towards achieving the goal of training situational awareness skills.

Kashyap, Sujatha

2000-01-01T23:59:59.000Z

123

The Nuclear Renaissance - Implications on Quantitative Nondestructive Evaluations  

Science Conference Proceedings (OSTI)

The world demand for energy is growing rapidly, particularly in developing countries that are trying to raise the standard of living for billions of people, many of whom do not even have access to electricity. With this increased energy demand and the high and volatile price of fossil fuels, nuclear energy is experiencing resurgence. This so-called nuclear renaissance is broad based, reaching across Asia, the United States, Europe, as well as selected countries in Africa and South America. Some countries, such as Italy, that have actually turned away from nuclear energy are reconsidering the advisability of this design. This renaissance provides the opportunity to deploy more advanced reactor designs that are operating today, with improved safety, economy, and operations. In this keynote address, I will briefly present three such advanced reactor designs in whose development Westinghouse is participating. These designs include the advanced passive PWR, AP1000, which recently received design certification for the US Nuclear Regulatory Commission; the Pebble Bed Modular reactor (PBMR) which is being demonstrated in South Africa; and the International Reactor Innovative and Secure (IRIS), which was showcased in the US Department of Energy's recently announced Global Nuclear Energy Partnership (GNEP), program. The salient features of these designs that impact future requirements on quantitative nondestructive evaluations will be discussed. Such features as reactor vessel materials, operating temperature regimes, and new geometric configurations will be described, and mention will be made of the impact on quantitative nondestructive evaluation (NDE) approaches.

Matzie, Regis A. [Westinghouse Electric Company, 20 International Drive, Windsor, CT 06095 (United States)

2007-03-21T23:59:59.000Z

124

Quantitative dynamic modeling of transcriptional networks of embryonic stem cells using integrated framework of Pareto optimality and energy balance  

E-Print Network (OSTI)

Embryonic Stem Cells (ESCs) are pluripotent and thus are considered the "cell type of choice". ESCs exhibit several phenotypic traits (e.g., proliferation, differentiation, apoptosis, necrosis, etc.) and when differentiated ...

Avila, Marco A., Ph. D. Massachusetts Institute of Technology

2009-01-01T23:59:59.000Z

125

Quantitative Methods for Comparing Different HVAC Control Schemes  

E-Print Network (OSTI)

Experimentally comparing the energy usage and comfort characteristics of different controllers in heating, ventilation, and air-conditioning (HVAC) systems is difficult because variations in weather and occupancy conditions preclude the possibility of establishing equivalent experimental conditions across the order of hours, days, and weeks. This paper is concerned with defining quantitative metrics of energy usage and occupant comfort, which can be computed and compared in a rigorous manner that is capable of determining whether differences between controllers are statistically significant in the presence of such environmental fluctuations. Experimental case studies are presented that compare two alternative controllers (a schedule controller and a hybrid system learning-based model predictive controller) to the default controller in a building-wide HVAC system. Lastly, we discuss how our proposed methodology may also be able to quantify the efficiency of other building automation systems.

Aswani, Anil; Taneja, Jay; Krioukov, Andrew; Culler, David; Tomlin, Claire

2012-01-01T23:59:59.000Z

126

A Quantitative Analysis of the Used-Car Market ?  

E-Print Network (OSTI)

We quantitatively investigate theallocative andwelfare effects of secondarymarkets for cars. An important source of gains from trade in these markets is the heterogeneity in the willingness to pay for higher-quality (newer) goods, but transaction costs are an impedimenttoinstantaneoustrade. Weexplorehowtheincomedistributionaffectsthis heterogeneity—income is an important determinant of willingness to pay for quality. Calibration of themodel successfullymatches several aggregate features of theU.S. and French used-car markets. Counterfactual analyses show that transaction costs have a large effect on volume of trade, allocations, and the primary market. Aggregate effects on consumer surplus and welfare are relatively small, but the effect on lower-income households can be large. Thanks to Chad Syverson for insightful discussions and to Alistair Wilson for excellent research assistance. NSF support is gratefully acknowledged.

Ro Gavazza Aless; Ro Lizzeri Nikita Roketskiy

2012-01-01T23:59:59.000Z

127

Quantitative analysis of forest island pattern in selected Ohio landscapes  

Science Conference Proceedings (OSTI)

The purpose of this study was to quantitatively describe the various aspects of regional distribution patterns of forest islands and relate those patterns to other landscape features. Several maps showing the forest cover of various counties in Ohio were selected as representative examples of forest patterns to be quantified. Ten thousand hectare study areas (landscapes) were delineated on each map. A total of 15 landscapes representing a wide variety of forest island patterns was chosen. Data were converted into a series of continuous variables which contained information pertinent to the sizes, shape, numbers, and spacing of woodlots within a landscape. The continuous variables were used in a factor analysis to describe the variation among landscapes in terms of forest island pattern. The results showed that forest island patterns are related to topography and other environmental features correlated with topography.

Bowen, G.W.; Burgess, R.L.

1981-07-01T23:59:59.000Z

128

Integration of hydrothermal energy economics related quantitative studies  

DOE Green Energy (OSTI)

An evaluation of the existing hydrothermal energy economics related quantitative studies is provided. The objective is to present the similarities and differences in methodology and assumptions, and explain the impact of these differences on the energy price estimates. A brief summary of the study categories, economic evaluation methodology, technical and economic assumptions and major outputs of the studies is presented. The relative importance and the likely effects of the most important technical and economic factors on the cost of energy are discussed. The sensitivity analysis results provided are useful in judging the credibility as well as the relative weaknesses and strengths of the various cost of energy estimation studies. The major conclusions of the evaluation and the recommendations for future research are presented.

Not Available

1982-10-01T23:59:59.000Z

129

A quantitative Kirkpatrick Level 1 and 2 study of equipment specialist apprentice operations training.  

E-Print Network (OSTI)

?? The primary purpose of the quantitative experimental study is to compare employee-learning outcomes for a course of study that is offered in two formats:… (more)

Hughes, Dirk D.

2012-01-01T23:59:59.000Z

130

arXiv.org - The Quantitative Finance (q-fin) archive (12/2008...  

NLE Websites -- All DOE Office Websites (Extended Search)

Derivatives Research, Evnine & Associates Peter Carr Head of Quantitative Research, Bloomberg LP Director of Math Finance Program, NYU Courant Institute J. Doyne Farmer...

131

Nursing home leadership styles and performance outcomes| A quantitative study about leader relationships.  

E-Print Network (OSTI)

?? This quantitative multivariate correlational research study used data about nursing home quality from the Centers for Medicare and Medicaid Services and data collected with… (more)

Olinger, Jean Lorraine

2011-01-01T23:59:59.000Z

132

BMC Evolutionary Biology BioMed Central Correction  

E-Print Network (OSTI)

Quantitative genetic analysis of life-history traits of Caenorhabditis elegans in stressful environments

Simon C Harvey; Alison Shorto; Mark E Viney

2009-01-01T23:59:59.000Z

133

Quantitative Financial Analysis of Alternative Energy Efficiency Shareholder Incentive Mechanisms  

SciTech Connect

Rising energy prices and climate change are central issues in the debate about our nation's energy policy. Many are demanding increased energy efficiency as a way to help reduce greenhouse gas emissions and lower the total cost of electricity and energy services for consumers and businesses. Yet, as the National Action Plan on Energy Efficiency (NAPEE) pointed out, many utilities continue to shy away from seriously expanding their energy efficiency program offerings because they claim there is insufficient profit-motivation, or even a financial disincentive, when compared to supply-side investments. With the recent introduction of Duke Energy's Save-a-Watt incentive mechanism and ongoing discussions about decoupling, regulators and policymakers are now faced with an expanded and diverse landscape of financial incentive mechanisms, Determining the 'right' way forward to promote deep and sustainable demand side resource programs is challenging. Due to the renaissance that energy efficiency is currently experiencing, many want to better understand the tradeoffs in stakeholder benefits between these alternative incentive structures before aggressively embarking on a path for which course corrections can be time-consuming and costly. Using a prototypical Southwest utility and a publicly available financial model, we show how various stakeholders (e.g. shareholders, ratepayers, etc.) are affected by these different types of shareholder incentive mechanisms under varying assumptions about program portfolios. This quantitative analysis compares the financial consequences associated with a wide range of alternative incentive structures. The results will help regulators and policymakers better understand the financial implications of DSR program incentive regulation.

Cappers, Peter; Goldman, Charles; Chait, Michele; Edgar, George; Schlegel, Jeff; Shirley, Wayne

2008-08-03T23:59:59.000Z

134

Evaluation of Performance Traits in Brahman Cattle: Blood Parameters, Calf Temperament, Residual Feed Intake, and Bull Reproductive Development  

E-Print Network (OSTI)

The objectives of these studies were (1) evaluate the relationship between temperament, blood parameters, and performance in Brahman calves (n = 300); (2) evaluate the relationship between residual feed intake (RFI) and reproductive development in Brahman bulls (n = 41). Serum was collected at 24 h and d 21 to 24, and analyzed for total protein (TP) immunoglobulin G (IgG), and cortisol (CS). Calves were weighed at 24 h, weighed and evaluated for temperament using exit velocity (EV) at d 21 to 24, and at 28 d intervals thereafter. Beginning 28 d prior to weaning, and at 28 d intervals through 56 d post-weaning calves were evaluated for pen score (PS) used to calculate temperament score (TS = (EV+PS)/2). The average TS from 28 d prior to weaning and weaning was used to generate temperament groups; calves 1 SD below the mean being calm, those 1 SD above the mean being temperamental and all remaining classified as intermediate. Calf TS influenced WW (P = 0.04) and ADG from birth to weaning (P = 0.03). Serum TP at 24 h affected (P 0.05) by TS. Residual feed intake classification did not influence (P > 0.05) age at reproductive milestones. Ultrasound carcass traits were not affected by TS or RFI. Serum TP at 24 h was a viable indicator of future growth performance. Temperamental animals had lower growth rates in both studies. Reproductive development was not affected by RFI. BW at reproductive milestones was lower in temperamental bulls.

Matheney, Kara J.

2009-08-01T23:59:59.000Z

135

Genome resequencing in Populus: Revealing large-scale genome variation and implications on specialized-trait genomics  

Science Conference Proceedings (OSTI)

To date, Populus ranks among a few plant species with a complete genome sequence and other highly developed genomic resources. With the first genome sequence among all tree species, Populus has been adopted as a suitable model organism for genomic studies in trees. However, far from being just a model species, Populus is a key renewable economic resource that plays a significant role in providing raw materials for the biofuel and pulp and paper industries. Therefore, aside from leading frontiers of basic tree molecular biology and ecological research, Populus leads frontiers in addressing global economic challenges related to fuel and fiber production. The latter fact suggests that research aimed at improving quality and quantity of Populus as a raw material will likely drive the pursuit of more targeted and deeper research in order to unlock the economic potential tied in molecular biology processes that drive this tree species. Advances in genome sequence-driven technologies, such as resequencing individual genotypes, which in turn facilitates large scale SNP discovery and identification of large scale polymorphisms are key determinants of future success in these initiatives. In this treatise we discuss implications of genome sequence-enable technologies on Populus genomic and genetic studies of complex and specialized-traits.

Muchero, Wellington [ORNL; Labbe, Jessy L [ORNL; Priya, Ranjan [University of Tennessee, Knoxville (UTK); DiFazio, Steven P [West Virginia University, Morgantown; Tuskan, Gerald A [ORNL

2013-01-01T23:59:59.000Z

136

A quantitative judgement system based on an association mechanism for natural conversation with computer  

Science Conference Proceedings (OSTI)

In this paper, a method for realizing judgements relating to quantity is proposed as one type of common-sense judgement made by humans. Humans manipulate smooth communications by retrieving, understanding and judging quantitative characteristics from ... Keywords: concept base, degree of association, knowledge base, quantitative judgement system, unknown word processing

Seiji Tsuchiya; Hirokazu Watabe; Tsukasa Kawaoka

2007-02-01T23:59:59.000Z

137

Evaluating quantitative and qualitative models: An application for nationwide water erosion assessment in Ethiopia  

Science Conference Proceedings (OSTI)

This paper tests the candidacy of one qualitative response model and two quantitative models for a nationwide water erosion hazard assessment in Ethiopia. After a descriptive comparison of model characteristics the study conducts a statistical comparison ... Keywords: Model comparison, Qualitative response models, Quantitative models

B. G. J. S. Sonneveld; M. A. Keyzer; L. Stroosnijder

2011-10-01T23:59:59.000Z

138

All-optical quantitative framework for bioluminescence tomography with non-contact measurement  

Science Conference Proceedings (OSTI)

In this contribution, we present an all-optical quantitative framework for bioluminescence tomography with non-contact measurement. The framework is comprised of four indispensable steps: extraction of the geometrical structures of the subject, light ... Keywords: All-optical, bioluminescence tomography, non-contact, quantitative framework, surface extraction

Xue-Li Chen; Heng Zhao; Xiao-Chao Qu; Duo-Fang Chen; Xiao-Rui Wang; Ji-Min Liang

2012-02-01T23:59:59.000Z

139

Quantitative NMR analysis of the protein G B1 domain in Xenopus laevis egg extracts  

E-Print Network (OSTI)

Quantitative NMR analysis of the protein G B1 domain in Xenopus laevis egg extracts and intact introduce a eukaryotic cellular system, the Xenopus laevis oocyte, for in-cell NMR analyses of biomolecules of in vivo NMR measurements in this cell type. This approach enables quantitative NMR experiments at defined

Ruderman, Joan

140

Quantitative Assessment of Range Fluctuations in Charged Particle Lung Irradiation  

SciTech Connect

Purpose: Water equivalent path length (WEL) variations due to respiration can change the range of a charged particle beam and result in beam overshoot to critical organs or beam undershoot to tumor. We have studied range fluctuations by analyzing four-dimensional computed tomography data and quantitatively assessing potential beam overshoot. Methods and Materials: The maximal intensity volume is calculated by combining the gross tumor volume contours at each respiratory phase in the four-dimensional computed tomography study. The first target volume calculates the maximal intensity volume for the entire respiratory cycle (internal target volume [ITV]-radiotherapy [RT]), and the second target volume is the maximal intensity volume corresponding to gated RT (gated-RT, {approx}30% phase window around exhalation). A compensator at each respiratory phase is calculated. Two 'composite' compensators for ITV-RT and gated-RT are then designed by selecting the minimal compensator depth at the respective respiratory phase. These compensators are then applied to the four-dimensional computed tomography data to estimate beam penetration. Analysis metrics include range fluctuation and overshoot volume, both as a function of gantry angle. We compared WEL fluctuations observed in treating the ITV-RT versus gated-RT in 11 lung patients. Results: The WEL fluctuations were <21.8 mm-WEL and 9.5 mm-WEL for ITV-RT and gated-RT, respectively for all patients. Gated-RT reduced the beam overshoot volume by approximately a factor of four compared with ITV-RT. Such range fluctuations can affect the efficacy of treatment and result in an excessive dose to a distal critical organ. Conclusion: Time varying range fluctuation analysis provides information useful for determining appropriate patient-specific treatment parameters in charged particle RT. This analysis can also be useful for optimizing planning and delivery.

Mori, Shinichiro [Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (United States)], E-mail: shinshin@nirs.go.jp; Wolfgang, John; Lu, H.-M.; Schneider, Robert; Choi, Noah C.; Chen, George T.Y. [Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (United States)

2008-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "quantitative trait loci" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


141

Predicting the impacts of climate change on animal distributions: the importance of local adaptation and species' traits  

SciTech Connect

The geographic range limits of many species are strongly affected by climate and are expected to change under global warming. For species that are able to track changing climate over broad geographic areas, we expect to see shifts in species distributions toward the poles and away from the equator. A number of ecological and evolutionary factors, however, could restrict this shifting or redistribution under climate change. These factors include restricted habitat availability, restricted capacity for or barriers to movement, or reduced abundance of colonists due the perturbation effect of climate change. This research project examined the last of these constraints - that climate change could perturb local conditions to which populations are adapted, reducing the likelihood that a species will shift its distribution by diminishing the number of potential colonists. In the most extreme cases, species ranges could collapse over a broad geographic area with no poleward migration and an increased risk of species extinction. Changes in individual species ranges are the processes that drive larger phenomena such as changes in land cover, ecosystem type, and even changes in carbon cycling. For example, consider the poleward range shift and population outbreaks of the mountain pine beetle that has decimated millions of acres of Douglas fir trees in the western US and Canada. Standing dead trees cause forest fires and release vast quantities of carbon to the atmosphere. The beetle likely shifted its range because it is not locally adapted across its range, and it appears to be limited by winter low temperatures that have steadily increased in the last decades. To understand range and abundance changes like the pine beetle, we must reveal the extent of adaptive variation across species ranges - and the physiological basis of that adaptation - to know if other species will change as readily as the pine beetle. Ecologists tend to assume that range shifts are the dominant response of species to climate change, but our experiments suggest that other processes may act in some species that reduce the likelihood of geographic range change. In the first part of our DOE grant (ending 2008) we argued that the process of local adaptation of populations within a species range, followed by climatic changes that occur too quickly for adaptive evolution, is an underappreciated mechanism by which climate change could affect biodiversity. When this process acts, species ranges may not shift readily toward the poles, slowing the rate of species and biome change. To test this claim, we performed an experiment comparing core and peripheral populations in a series of field observations, translocation experiments, and genetic analyses. The papers in Appendix A were generated from 2005-2008 funding. In the second part of the DOE grant (ending 2011) we studied which traits promote population differentiation and local adaptation by building genomic resources for our study species and using these resources to reveal differences in gene expression in peripheral and core populations. The papers in Appendix B were generated from 2008-2011 funding. This work was pursued with two butterfly species that have contrasting life history traits (body size and resource specialization) and occupy a common ecosystem and a latitudinal range. These species enabled us to test the following hypotheses using a single phylogenetic group.

HELLMANN, J. J.; LOBO, N. F.

2011-12-20T23:59:59.000Z

142

Quantitative Methodology for Assessing State-Level Nuclear Security Measures  

E-Print Network (OSTI)

The international community faces a growing threat from nuclear terrorism. The complexity of the threats of nuclear terrorism, the variety of nuclear security measures that States can devote resources towards to address the threats, and the limited resources States have to invest in these nuclear security measures make it imperative that resources are applied in the most effective way possible. In this dissertation, we develop a quantitative, risk-based methodology that States can employ to gain a better understanding of the nuclear threat they face, assist them in determining what nuclear security measures they should invest in, and facilitate communication to stake-holders to request and justify investment in these measures. The risk-based methodology has been developed employing a combination of pathways analysis, game-theory, multiple-attribute utility analysis, decision theory and risk analysis. The methodology was designed to account for the wide variety of nuclear security measures that States can invest in, the range of possible consequences from different nuclear threats, and the severity of these consequences to the State. In addition, the methodology models the adversary's strategic decision making while accounting for the capabilities, motivations, and disincentives that may influence which nuclear threat a terrorist group will attempt. The methodology is introduced into a Visual Basic for Applications code, which we demonstrate through verification and qualitative validation tests. We then develop three State nuclear infrastructures with varying levels of complexity, meant to provide a realistic representation of real-world States. We then utilize the code to evaluate the risk of nuclear terrorism against terrorist threats that have different motivations for nuclear terrorism to demonstrate how different motivations for nuclear terrorism may affect both State-level risk and the State's optimal risk-reduction strategy. These risk analyses are then used to both evaluate various nuclear security strategies and determine which nuclear security measures will have the greatest risk-reduction value. Finally, we conduct a sensitivity analysis on capabilities of terrorist groups to understand how changes in these capabilities affect the State-level risk from nuclear terrorism.

Myers, Christopher 1985-

2012-12-01T23:59:59.000Z

143

QUANTITATIVE REMOTE SENSING: HORNS REV WIND FARM CASE STUDY C. B. Hasager, M. Nielsen, M. B. Christiansen  

E-Print Network (OSTI)

QUANTITATIVE REMOTE SENSING: HORNS REV WIND FARM CASE STUDY C. B. Hasager, M. Nielsen, M. B of quantitative remote sensing for wind resource estimation. 1. INTRODUCTION Possibilities and limitations

144

Development of a quantitative PCR method to differentiate between viable and nonviable bacteria in environmental water samples  

E-Print Network (OSTI)

Development of a quantitative PCR method to differentiateof polymerase chain reaction (PCR) and quantitative polymer-such as reverse transcriptase PCR (RT-PCR or RT-qPCR), these

Gedalanga, Phillip B.; Olson, Betty H.

2009-01-01T23:59:59.000Z

145

Inferring molecular interactions pathways from eQTL data  

SciTech Connect

Analysis of expression quantitative trait loci (eQTL) helps elucidate the connection between genotype, gene expression levels, and phenotype. However, standard statistical genetics can only attribute changes in expression levels to loci on the genome, not specific genes. Each locus can contain many genes, making it very difficult to discover which gene is controlling the expression levels of other genes. Furthermore, it is even more difficult to find a pathway of molecular interactions responsible for controlling the expression levels. Here we describe a series of techniques for finding explanatory pathways by exploring graphs of molecular interactions. We show several simple methods can find complete pathways the explain the mechanism of differential expression in eQTL data.

Rashid, Imran; McDermott, Jason E.; Samudrala, Ram

2009-04-20T23:59:59.000Z

146

Influence of GPS Precipitable Water Vapor Retrievals on Quantitative Precipitation Forecasting in Southern California  

Science Conference Proceedings (OSTI)

The effects of precipitable water vapor (PWV) retrievals from the Southern California Integrated GPS Network (SCIGN) on quantitative precipitation forecast (QPF) skill are examined over two flood-prone regions of Southern California: Santa ...

Steven Marcus; Jinwon Kim; Toshio Chin; David Danielson; Jayme Laber

2007-11-01T23:59:59.000Z

147

BMA Probabilistic Quantitative Precipitation Forecasting over the Huaihe Basin Using TIGGE Multi-model Ensemble Forecasts  

Science Conference Proceedings (OSTI)

Bayesian model averaging (BMA) probability quantitative precipitation forecast (PQPF) models were established by calibrating their parameters using one- to seven-day ensemble forecasts of 24-hour accumulated precipitation, and observations from 43 ...

Jianguo Liu; Zhenghui Xie

148

Quantitative Spatiotemporal Evaluation of Dynamically Downscaled MM5 Precipitation Predictions over the Tampa Bay Region, Florida  

Science Conference Proceedings (OSTI)

This research quantitatively evaluated the ability of the fifth-generation Pennsylvania State University–National Center for Atmospheric Research Mesoscale Model (MM5) to reproduce observed spatiotemporal variability of precipitation in the Tampa ...

Syewoon Hwang; Wendy Graham; José L. Hernández; Chris Martinez; James W. Jones; Alison Adams

2011-12-01T23:59:59.000Z

149

Quantitative Precipitation Forecasting for the Tennessee and Cumberland River Watersheds Using the NCEP Regional Spectral Model  

Science Conference Proceedings (OSTI)

A limited-area spectral model—the Regional Spectral Model—developed at the National Centers for Environmental Prediction is used to prepare daily quantitative precipitation forecasts out to 48 h for the Tennessee and Cumberland River basins in ...

Qi Mao; Stephen F. Mueller; Hann-Ming Henry Juang

2000-02-01T23:59:59.000Z

150

Quantitative Precipitation Estimation in the CASA X-band Dual-Polarization Radar Network  

Science Conference Proceedings (OSTI)

This paper presents the sensing aspects and performance evaluation of the quantitative precipitation estimation (QPE) system in an X-band dual-polarization radar network developed by the Collaborative Adaptive Sensing of the Atmosphere (CASA) ...

Yanting Wang; V. Chandrasekar

2010-10-01T23:59:59.000Z

151

arXiv.org - The Quantitative Biology archive (9/03)  

NLE Websites -- All DOE Office Websites (Extended Search)

archive (903) The Quantitative Biology archive (q-bio) was introduced 15 Sep 2003. Subject categories of the q-bio archive: BM - Biomolecules DNA, RNA, proteins, lipids, etc.;...

152

Distributed Quantitative Precipitation Forecasting Using Information from Radar and Numerical Weather Prediction Models  

Science Conference Proceedings (OSTI)

The benefits of short-term (1–6 h), distributed quantitative precipitation forecasts (DQPFs) are well known. However, this area is acknowledged to be one of the most challenging in hydrometeorology. Previous studies suggest that the “state of the ...

Auroop R. Ganguly; Rafael L. Bras

2003-12-01T23:59:59.000Z

153

Quantitative Microwave Backscatter Measurements from the Ocean Surface Using Digital Marine Radar Images  

Science Conference Proceedings (OSTI)

The capabilities for quantitative measurements of the ocean backscatter at low grazing angles of a conventional low-budget X-band marine radar associated with a commercial digital capture board are investigated. Details are given of the external ...

C. P. Gommenginger; N. P. Ward; G. J. Fisher; I. S. Robinson; S. R. Boxall

2000-05-01T23:59:59.000Z

154

The Quantitative Use of PIREPs in Developing Aviation Weather Guidance Products  

Science Conference Proceedings (OSTI)

An evaluation of the utility of pilot reports (PIREPs) of weather for aviation forecasting product development is presented. Although PIREPs were never intended for quantitative use, this limitation has not prevented developers of improved ...

Barry Schwartz

1996-09-01T23:59:59.000Z

155

Improving Quantitative Precipitation Forecasts in the Warm Season: A USWRP Research and Development Strategy  

Science Conference Proceedings (OSTI)

Warm-season quantitative precipitation forecasts (QPFs) are the poorest performance area of forecast systems worldwide. They stubbornly fall further behind while other aspects of weather prediction steadily improve. Unless a major effort is ...

J. Michael Fritsch; R. E. Carbone

2004-07-01T23:59:59.000Z

156

A quantitative assessment of nuclear weapons proliferation risk utilizing probabilistic methods  

E-Print Network (OSTI)

A comparative quantitative assessment is made of the nuclear weapons proliferation risk between various nuclear reactor/fuel cycle concepts using a probabilistic method. The work presented details quantified proliferation ...

Sentell, Dennis Shannon, 1971-

2002-01-01T23:59:59.000Z

157

Implications of Ensemble Quantitative Precipitation Forecast Errors on Distributed Streamflow Forecasting  

Science Conference Proceedings (OSTI)

Evaluating the propagation of errors associated with ensemble quantitative precipitation forecasts (QPFs) into the ensemble streamflow response is important to reduce uncertainty in operational flow forecasting. In this paper, a multifractal ...

Giuseppe Mascaro; Enrique R. Vivoni; Roberto Deidda

2010-02-01T23:59:59.000Z

158

Reliable Probabilistic Quantitative Precipitation Forecasts from a Short-Range Ensemble Forecasting System  

Science Conference Proceedings (OSTI)

A simple binning technique is developed to produce reliable 3-h probabilistic quantitative precipitation forecasts (PQPFs) from the National Centers for Environmental Prediction (NCEP) multimodel short-range ensemble forecasting system obtained ...

David J. Stensrud; Nusrat Yussouf

2007-02-01T23:59:59.000Z

159

Spatially resolved quantitative rheo-optics of complex fluids in a microfluidic device  

E-Print Network (OSTI)

In this study, we use microparticle image velocimetry (?-PIV) and adapt a commercial birefringence microscopy system for making full-field, quantitative measurements of flow-induced birefringence (FIB) for the purpose of ...

Ober, Thomas Joseph

160

Comparison of Methods Used to Generate Probabilistic Quantitative Precipitation Forecasts over South America  

Science Conference Proceedings (OSTI)

In this work, the quality of several probabilistic quantitative precipitation forecasts (PQPFs) is examined. The analysis is focused over South America during a 2-month period in the warm season. Several ways of generating and calibrating the ...

Juan Ruiz; Celeste Saulo; Eugenia Kalnay

2009-02-01T23:59:59.000Z

Note: This page contains sample records for the topic "quantitative trait loci" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


161

Evaluation of 33 Years of Quantitative Precipitation Forecasting at the NMC  

Science Conference Proceedings (OSTI)

The National Meteorological Center (NMC) initiated Quantitative Precipitation Forecasts (QPF) and an intensive QPF verification program in 1960. These forecast products have evolved from a manual effort, relying on extensive forecast experience ...

David A. Olson; Norman W. Junker; Brian Korty

1995-09-01T23:59:59.000Z

162

Evaluation of Short-Range Quantitative Precipitation Forecasts from a Time-Lagged Multimodel Ensemble  

Science Conference Proceedings (OSTI)

Short-range quantitative precipitation forecasts (QPFs) and probabilistic QPFs (PQPFs) are investigated for a time-lagged multimodel ensemble forecast system. One of the advantages of such an ensemble forecast system is its low-cost generation of ...

Huiling Yuan; Chungu Lu; John A. McGinley; Paul J. Schultz; Brian D. Jamison; Linda Wharton; Christopher J. Anderson

2009-02-01T23:59:59.000Z

163

Comparative Verification of Guidance and Local Quantitative Precipitation Forecasts: Calibration Analyses  

Science Conference Proceedings (OSTI)

A comparative verification is reported of 2631 matched pairs of quantitative precipitation forecasts (QPFs) prepared daily from 1 October 1992 to 31 October 1996 by the Hydrometeorological Prediction Center (HPC) and the Weather Service Forecast ...

Roman Krzysztofowicz; Ashley A. Sigrest

1999-06-01T23:59:59.000Z

164

A quantitative evaluation of fixed-pattern noise reduction methods in imaging systems  

Science Conference Proceedings (OSTI)

Fixed-pattern noise is a common feature in several uncalibrated imaging systems, and it typically appears as striping and grid-like nonuniformity artifacts in hyperspectral and infrared cameras. In this work, we present a quantitative and comparative ...

Pablo Meza; César San Martin; Esteban Vera; Sergio Torres

2010-11-01T23:59:59.000Z

165

Real-time quantitative PCR for enteric adenovirus serotype 40 in environmental waters  

E-Print Network (OSTI)

adenovirus detection by PCR as an index of human viruses.polluted waters by nested PCR amplification. Appl. Environ.real-time quantitative PCR. J. Clin. Microbiol. Wigand, R. ,

Jiang, Sunny C; Dezfulian, H; Chu, W P

2005-01-01T23:59:59.000Z

166

High-Resolution GFS-Based MOS Quantitative Precipitation Forecasts on a 4-km Grid  

Science Conference Proceedings (OSTI)

The Meteorological Development Laboratory (MDL) of the National Weather Service (NWS) has developed high-resolution Global Forecast System (GFS)-based model output statistics (MOS) 6- and 12-h quantitative precipitation forecast (QPF) guidance on ...

Jerome P. Charba; Frederick G. Samplatsky

2011-01-01T23:59:59.000Z

167

On the Quantitative Low-Level Aerosol Measurements Using Ceilometer-Type Lidar  

Science Conference Proceedings (OSTI)

The objective of this work is to investigate whether a commercial ceilometer-type lidar can be used as a quantitative aerosol measurement instrument. To this end, lidar backscattering measurements are compared with exact theoretical calculations ...

Anu-Maija Sundström; Timo Nousiainen; Tuukka Petäjä

2009-11-01T23:59:59.000Z

168

Quantitative characterization of pulverized coal and biomasscoal blends in pneumatic conveying pipelines using electrostatic sensor arrays and data fusion techniques  

E-Print Network (OSTI)

Quantitative characterization of pulverized coal and biomass­coal blends in pneumatic conveying.1088/0957-0233/23/8/085307 Quantitative characterization of pulverized coal and biomass­coal blends in pneumatic conveying pipelines using Quantitative data about the dynamic behaviour of pulverized coal and biomass­coal blends in fuel injection

Yan, Yong

169

Population Structure, Association Mapping of Economic Traits and Landscape Genomics of East Texas Loblolly Pine ( Pinus taeda L.)  

E-Print Network (OSTI)

Loblolly pine (Pinus taeda L.) is an ecologically and economically important southern pine, distributed across the southeastern United States. Its genetic improvement for breeding and deployment is a major goal of the Western Gulf Forest Tree Improvement Program (WGFTIP) hosted by the Texas A&M Forest Service. Rapid advances in genomics and molecular marker technology have created potential for application of Marker Assisted Selection (MAS) and Genomic Selection (GS) for accelerated breeding in forest trees. First-generation selection (FGS) and second- generation selection (SGS) breeding populations of loblolly pine from east Texas were studied to estimate the genetic diversity, population structure, linkage disequilibrium (LD), signatures of selection and association of breeding traits with genetic markers using a genome-wide panel of 4264 single nucleotide polymorphisms (SNPs). Under- standing the genetic basis of local adaptation is crucial to disentangle the dynamics of gene flow, drift and selection and to address climate change. Bayesian mixed linear models and logistic regression were used to associate SNP variation with geography, climate, aridity and growth season length and markers with strong correlations were investigated for biological functions. Relatively high levels of observed (Ho = 0.178–0.198) and expected (He = 0.180-0.198) heterozygosities were found in all populations. The amount of inbreeding was very low, and many populations exhibited a slight excess of heterozygotes. The population substructure was weak, but FST indicated more pronounced differentiation in the SGS populations. As expected for outcrossing natural populations, the genome-wide LD was low, but marker density was insufficient to deduce the decay rate. Numerous associations were found between various phenotypes and SNPs, but few remained significant after false positive correction. Signatures of diversifying and balancing selection were found in markers representing important biological functions. Strong correlations supported by Bayes factors were found between various environmental variables and several SNPs. Logistic regression found hundreds of significant marker-environment associations, but none remained significant after false-positive correction, which was likely too stringent and will require further investigation. Annotations of significant markers implicated them in crucial biological functions. These results present the first step in the application of MAS to the WGFTIP for loblolly pine genetic improvement and will contribute to the knowledgebase necessary for genomic selection technology. Results from environmental association study provide important information for designing breeding strategies to address climate change and for genetic conservation purposes.

Chhatre, Vikram E.

2013-05-01T23:59:59.000Z

170

Quantitative determination of mineral composition by powder x-ray diffraction  

DOE Patents (OSTI)

An external standard intensity ratio method is used for quantitatively determining mineralogic compositions of samples by x-ray diffraction. The method uses ratios of x-ray intensity peaks from a single run. Constants are previously determined for each mineral which is to be quantitatively measured. Ratios of the highest intensity peak of each mineral to be quantified in the sample and the highest intensity peak of a reference mineral contained in the sample are used to calculate sample composition.

Pawloski, G.A.

1984-08-10T23:59:59.000Z

171

Quantitative determination of mineral composition by powder X-ray diffraction  

DOE Patents (OSTI)

An external standard intensity ratio method is used for quantitatively determining mineralogic compositions of samples by x-ray diffraction. The method uses ratios of x-ray intensity peaks from a single run. Constants are previously determined for each mineral which is to be quantitatively measured. Ratios of the highest intensity peak of each mineral to be quantified in the sample and the highest intensity peak of a reference mineral contained in the sample are used to calculate sample composition.

Pawloski, Gayle A. (Livermore, CA)

1986-01-01T23:59:59.000Z

172

Qualitative and Quantitative Management Tools Used by Financial Officers in Public Research Universities  

E-Print Network (OSTI)

This dissertation set out to identify effective qualitative and quantitative management tools used by financial officers (CFOs) in carrying out their management functions of planning, decision making, organizing, staffing, communicating, motivating, leading and controlling at a public research university. In addition, impediments to the use of these tools were identified which may assist in breaking down barriers to the implementation of these tools within higher education. The research endeavor also provided additional significance through the CFOs identifying benefits from the use of quantitative and qualitative management tools. Finally, the study undertook the task of identifying quantitative and qualitative management tools the important to public research university CFOs in carrying out their management functions in the future. In this study, the Delphi method was used to gain consensus from a panel of fifteen public research university CFOs who were experts on qualitative and quantitative management tools. The experts were self-identified through their response to a questionnaire on their use of the management tools and represented 12 different states. Due to the nature of the research, a computer-based Delphi method was used to facilitate a four round, electronically based Delphi study. The questionnaires were based upon a review of the literature and tested by a pilot group of higher education CFOs. Through a series of four electronic questionnaires, the Delphi panel identified twenty-three qualitative and quantitative management tools which they believe are moderately effective for use by public research university CFOs in carrying out their functions of planning, decision making, organizing, staffing, communicating, motivating, leading and controlling. Additionally, the panel of experts identified sixteen barriers/impediments to the use of qualitative and quantitative tools in carrying out the above functions. The panel also identified eighteen benefits that the tools provide to public research university CFOs in carrying out their management functions. Finally, the Delphi panel identified three qualitative and quantitative management tools that will be highly important, and twenty qualitative and quantitative management tools that the panel of experts considered to be important, for public research university CFOs in carrying out their management functions in the future. This dissertation study is significant because the results are expected to provide public research university CFOs qualitative and quantitative management tools that they may use to assist them in carrying out their management functions. The barriers/impediments and benefits noted also provide CFOs with knowledge to assess whether the tools can be used at their institutions, knowing the specific climate and culture which exists. The qualitative and quantitative management tools which were identified as being important in the future can serve as a guide to develop training programs to enhance the knowledge of public research university CFOs.

Trexler, Grant 1961-

2012-12-01T23:59:59.000Z

173

The Application of Traits-Based Assessment Approaches to Estimate the Effects of Hydroelectric Turbine Passage on Fish Populations  

DOE Green Energy (OSTI)

One of the most important environmental issues facing the hydropower industry is the adverse impact of hydroelectric projects on downstream fish passage. Fish that migrate long distances as part of their life cycle include not only important diadromous species (such as salmon, shads, and eels) but also strictly freshwater species. The hydropower reservoirs that downstream-moving fish encounter differ greatly from free-flowing rivers. Many of the environmental changes that occur in a reservoir (altered water temperature and transparency, decreased flow velocities, increased predation) can reduce survival. Upon reaching the dam, downstream-migrating fish may suffer increased mortality as they pass through the turbines, spillways and other bypasses, or turbulent tailraces. Downstream from the dam, insufficient environmental flow releases may slow downstream fish passage rates or decrease survival. There is a need to refine our understanding of the relative importance of causative factors that contribute to turbine passage mortality (e.g., strike, pressure changes, turbulence) so that turbine design efforts can focus on mitigating the most damaging components. Further, present knowledge of the effectiveness of turbine improvements is based on studies of only a few species (mainly salmon and American shad). These data may not be representative of turbine passage effects for the hundreds of other fish species that are susceptible to downstream passage at hydroelectric projects. For example, there are over 900 species of fish in the United States. In Brazil there are an estimated 3,000 freshwater fish species, of which 30% are believed to be migratory (Viana et al. 2011). Worldwide, there are some 14,000 freshwater fish species (Magurran 2009), of which significant numbers are susceptible to hydropower impacts. By comparison, in a compilation of fish entrainment and turbine survival studies from over 100 hydroelectric projects in the United States, Winchell et al. (2000) found useful turbine passage survival data for only 30 species. Tests of advanced hydropower turbines have been limited to seven species - Chinook and coho salmon, rainbow trout, alewife, eel, smallmouth bass, and white sturgeon. We are investigating possible approaches for extending experimental results from the few tested fish species to predict turbine passage survival of other, untested species (Cada and Richmond 2011). In this report, we define the causes of injury and mortality to fish tested in laboratory and field studies, based on fish body shape and size, internal and external morphology, and physiology. We have begun to group the large numbers of unstudied species into a small number of categories, e.g., based on phylogenetic relationships or ecological similarities (guilds), so that subsequent studies of a few representative species (potentially including species-specific Biological Index Testing) would yield useful information about the overall fish community. This initial effort focused on modifying approaches that are used in the environmental toxicology field to estimate the toxicity of substances to untested species. Such techniques as the development of species sensitivity distributions (SSDs) and Interspecies Correlation Estimation (ICE) models rely on a considerable amount of data to establish the species-toxicity relationships that can be extended to other organisms. There are far fewer studies of turbine passage stresses from which to derive the turbine passage equivalent of LC{sub 50} values. Whereas the SSD and ICE approaches are useful analogues to predicting turbine passage injury and mortality, too few data are available to support their application without some form of modification or simplification. In this report we explore the potential application of a newer, related technique, the Traits-Based Assessment (TBA), to the prediction of downstream passage mortality at hydropower projects.

Cada, Glenn F [ORNL; Schweizer, Peter E [ORNL

2012-04-01T23:59:59.000Z

174

Quantitative Risk reduction estimation Tool For Control Systems, Suggested Approach and Research Needs  

SciTech Connect

For the past year we have applied a variety of risk assessment technologies to evaluate the risk to critical infrastructure from cyber attacks on control systems. More recently, we identified the need for a stand alone control system risk reduction estimation tool to provide owners and operators of control systems with a more useable, reliable, and credible method for managing the risks from cyber attack. Risk is defined as the probability of a successful attack times the value of the resulting loss, typically measured in lives and dollars. Qualitative and ad hoc techniques for measuring risk do not provide sufficient support for cost benefit analyses associated with cyber security mitigation actions. To address the need for better quantitative risk reduction models we surveyed previous quantitative risk assessment research; evaluated currently available tools; developed new quantitative techniques [17] [18]; implemented a prototype analysis tool to demonstrate how such a tool might be used; used the prototype to test a variety of underlying risk calculational engines (e.g. attack tree, attack graph); and identified technical and research needs. We concluded that significant gaps still exist and difficult research problems remain for quantitatively assessing the risk to control system components and networks, but that a useable quantitative risk reduction estimation tool is not beyond reach.

Miles McQueen; Wayne Boyer; Mark Flynn; Sam Alessi

2006-03-01T23:59:59.000Z

175

Manual for Quantitative Evaluation of the Co-Benefits Approach to Climate  

Open Energy Info (EERE)

Manual for Quantitative Evaluation of the Co-Benefits Approach to Climate Manual for Quantitative Evaluation of the Co-Benefits Approach to Climate Change Jump to: navigation, search LEDSGP green logo.png FIND MORE DIA TOOLS This tool is part of the Development Impacts Assessment (DIA) Toolkit from the LEDS Global Partnership. Tool Summary Name: Manual for Quantitative Evaluation of the Co-Benefits Approach to Climate Change Agency/Company /Organization: Ministry of Environment, Japan Sector: Climate, Energy User Interface: Other Complexity/Ease of Use: Moderate Cost: Free Related Tools Global Atmospheric Pollution Forum Air Pollutant Emission Inventory Manual for Social Impact Assessment of Land-Based Carbon Projects SEAGA Intermediate Level Handbook ... further results Manual that addresses the co-benefits approach to climate change; by

176

ANSI/ASHRAE/IES Standard 90.1-2010 Final Determination Quantitative  

NLE Websites -- All DOE Office Websites (Extended Search)

2010 Final Determination Quantitative 2010 Final Determination Quantitative Analysis The U.S. Department of Energy (DOE) conducted a final quantitative analysis to assess whether buildings constructed according to the requirements of ASHRAE Standard 90.1-2010 would result in energy savings compared with buildings constructed to ASHRAE Standard 90.1- 2007. The final analysis considered each of the 109 addenda to ASHRAE Standard 90.1-2007 that were included in ASHRAE Standard 90.1- 2010. All 109 addenda processed by ASHRAE in the creation of ASHRAE Standard 90.1-2010 from ASHRAE Standard 90.1-2007 were reviewed by DOE, and their combined impact on a suite of 16 building prototype models in 15 ASHRAE climate zones was considered. Most addenda were deemed to have little quantifiable impact on building efficiency for

177

Summary  

E-Print Network (OSTI)

Genetical metabolomics [metabolite profiling combined with quantitative trait locus (QTL) analysis] has been proposed as a new tool to identify loci that control metabolite abundances. This concept was evaluated in a case study with the model tree Populus. Using HPLC, the peak abundances were analyzed of 15 closely related flavonoids present in apical tissues of two full-sib poplar families, Populus deltoides cv. S9-2 · P. nigra cv. Ghoy and P. deltoides cv. S9-2 · P. trichocarpa cv. V24, and correlation and QTL analysis were used to detect flux control points in flavonoid biosynthesis. Four robust metabolite quantitative trait loci (mQTL), associated with rate-limiting steps in flavonoid biosynthesis, were mapped. Each mQTL was involved in the flux control to one or two flavonoids. Based on the identities of the affected metabolites and the flavonoid pathway structure, a tentative function was assigned to three of these mQTL, and the corresponding candidate genes were mapped. The data indicate that the combination of metabolite profiling with QTL analysis is a valuable tool to identify control points in a complex metabolic pathway of closely related compounds.

Kris Morreel; Geert Goeminne; Véronique Storme; Lieven Sterck; John Ralph; Peter Breyne; Michel Georges; Eric Messens; Wout Boerjan; Gent Belgium

2006-01-01T23:59:59.000Z

178

Apparatus and method for quantitatively evaluating total fissile and total fertile nuclide content in samples  

DOE Patents (OSTI)

Simultaneous photon and neutron interrogation of samples for the quantitative determination of total fissile nuclide and total fertile nuclide material present is made possible by the use of an electron accelerator. Prompt and delayed neutrons produced from resulting induced fissions are counted using a single detection system and allow the resolution of the contributions from each interrogating flux leading in turn to the quantitative determination sought. Detection limits for .sup.239 Pu are estimated to be about 3 mg using prompt fission neutrons and about 6 mg using delayed neutrons.

Caldwell, John T. (Los Alamos, NM); Kunz, Walter E. (Santa Fe, NM); Cates, Michael R. (Oak Ridge, TN); Franks, Larry A. (Santa Barbara, CA)

1985-01-01T23:59:59.000Z

179

A Study in Sorghum Bicolor: QTL Analysis of Photoperiod Sensitive Sorghums, Evaluation of Sorghum x Sugarcane Hybrids and Trait Introgression for Intergeneric Hybrid Improvement  

E-Print Network (OSTI)

Recently designated as a bioenergy crop, Sorghum is rather unique as it can produce large quantities of cellulose or sugar which can be used to produce advanced biofuels or compounds. Sweet sorghum contains high levels of sugars and biomass sorghums consist primarily of ligno-cellulosic biomass. Improvement of both sorghum types is essential for maximizing production and conversion efficiency. Photoperiod sensitive sorghum is thought to maximize biomass production yet maturity influence on biomass production and composition is not fully understood. Utilizing sorghum for sugar production has increased efforts to develop sweet sorghums with sugar yields similar to sugarcane. Hybridization of these species has been investigated with, until recently, little success. Testing newly developed intergeneric hybrids and improvement of parents used in their creation will determine their feasibility and improve hybrid performance. Objectives of this research are multifaceted. First, analyze photoperiod sensitive sorghum in varying day length environments to determine maturity effects on plant phenotype, composition, and QTL detection. Second, analyze intergeneric sorghum × sugarcane hybrids to determine agronomic performance in relation to sugarcane. Lastly, introgress the iap allele into sweet sorghum females for use in intergeneric hybrid creation. Photoperiod sensitive sorghum RILs were evaluated in College Station and Weslaco, Texas and Puerto Rico which caused differential expression of plant maturity. Genetic control of trait expression was high for each location. Results indicate gradual induction of plant maturity increases detection of phenotypic QTL and detection of compositional QTL increases when maturity effects on plant phenotype are reduced. Intergeneric sorghum × sugarcane F_1 hybrids were compared to sugarcane in Weslaco, Texas in 2011. Each hybrid expressed agronomic traits similar or better than that of the sugarcane variety. High levels of repeatability and genetic influence on trait expression were observed. Overall performance of the sugarcane variety was better than any individual hybrid tested. Introgression of iap into sweet sorghum was successful and generated seventeen new sweet sorghum female genotypes possessing the allele. Only two genotypes exhibited higher brix readings and both were later maturing than Tx3361. Height and maturity of all developed genotypes varied and desirability of developed lines was similar to Tx3361.

Bartek, Matthew

2013-08-01T23:59:59.000Z

180

An updated object oriented bovine QTL viewer and genome-wide bovine meta-analysis  

E-Print Network (OSTI)

Waves of bovine genomic data have been produced as a result of the bovine genome sequencing projects. In addition to the massive amounts of genomic sequence, significant annotation including single nucleotide polymorphisms, sequence tagged sites and haplotype blocks have been produced by the Bovine HapMap Project. Furthermore, many agriculturally significant traits in cattle such as milk yield and carcass weight are measured on a quantitative scale and have been genetically mapped as quantitative trait loci (QTL). QTL data can be used to generate another form of bovine annotation linking phenotype to genotype. However, it is impossible for humans to be able to analyze genomic scale data without computer based tools. Bioinformatic tools have been shown to greatly increase productivity and improve efficiency when dealing with large data sets. My dissertation presents an integrated, extensible database that houses SNPs, STSs, haplotypes, and QTL. The database is presented to researchers through a restructured, object oriented Bovine QTL Viewer that displays multiple levels of bovine annotation synergistically. Evaluation of use of the viewer was performed using a survey based approach and measured quantitatively. In addition, the QTL data from the database was used to analyze the frequency of gene ontology (GO) annotations within QTL regions. QTL regions were divided into 8 trait based groups. GO terms were counted within each category of QTL and in non- QTL regions of the genome. Top level GO term frequencies were generated from the counts and these frequencies were compared between QTL and non-QTL portions of the genome. Furthermore, specific sets of GO terms believed to be related to QTL categories were also used to determine if QTL regions were enriched for genes annotated with such GO terms. As a result, we determined that gene density varied significantly across QTL regions and that many QTL categories showed GO term frequency differences that could be related to the trait’s biology. Furthermore, our selected GO term sets were shown to be significantly enriched in some QTL categories.

Salih, Hanni

2008-08-01T23:59:59.000Z

Note: This page contains sample records for the topic "quantitative trait loci" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


181

Development of quantitative real time PCR to assess human brain microvascular endothelial cell susceptibility to HIV -1 infection  

E-Print Network (OSTI)

of Quantitative Real Time PCR to Assess Human Brainof the PCR assays.. 18and optimization of qRT-PCR assays specific for different

Chao, Ying Sheng

2008-01-01T23:59:59.000Z

182

Application of Phast in the Quantitative Consequence Analysis for the Boiler BLEVE  

Science Conference Proceedings (OSTI)

Boilers BLEVE are among the most devastating accidents likely in chemical process industry, which lead to shock waves and rocketing fragments of ruptured vessels. The prediction of the boiler explosion energy and its impact is fairly helpful to the prevention ... Keywords: boiler, BLEVE, Phast, quantitative assessment, blast-wave overpressure, positive phase impulse

Qu Fang, Zuo Zhe, Si Qingmin

2013-01-01T23:59:59.000Z

183

Evaluating maintenance policies by quantitative modeling and analysis Enrico Zio1,2,*  

E-Print Network (OSTI)

. It is shown that modeling and analysis provide information useful for setting a maintenance policy. 1 of the energy market, which has forced the producers to be more competitive by reacting promptly and reliablyEvaluating maintenance policies by quantitative modeling and analysis Enrico Zio1,2,* , Michele

Paris-Sud XI, Université de

184

Quantitative evaluation of general corrosion of Type 304 stainless steel in subcritical and  

E-Print Network (OSTI)

- sion, such as pitting and stress corrosion cracking. However, potential or current monitoring can onlyQuantitative evaluation of general corrosion of Type 304 stainless steel in subcritical the corrosion rate of Type 304 stainless steel (SS) in subcritical and supercritical environments. The EN

Benning, Liane G.

185

AN INSTRUMENTALIST APPROACH TO VALIDATION: A QUANTITATIVE ASSESSMENT OF A NOVEL COAL  

E-Print Network (OSTI)

AN INSTRUMENTALIST APPROACH TO VALIDATION: A QUANTITATIVE ASSESSMENT OF A NOVEL COAL GASIFICATION/uncertainty quantification (V&V/UQ) of codes is presented in detail, and is applied to a novel entrained flow coal at the mathematical model. The novel coal gasification model, which utilizes the direct quadrature method of moments

Utah, University of

186

Combining multiple classifiers to quantitatively rank the impact of abnormalities in flight data  

Science Conference Proceedings (OSTI)

This paper presents a novel two phase method that combines one class support vector machine classifiers using combination rules to quantitatively assess the degree of abnormality at various heights during individual aircraft descents and also over the ... Keywords: Aircraft landing guidance, Artificial intelligence, Fault diagnosis, Support vector machines

E. Smart; D. Brown; J. Denman

2012-08-01T23:59:59.000Z

187

Gas chromatograph-mass spectrometer (GC/MS) system for quantitative analysis of reactive chemical compounds  

DOE Patents (OSTI)

Described is a new gas chromatograph-mass spectrometer (GC/MS) system and method for quantitative analysis of reactive chemical compounds. All components of such a GC/MS system external to the oven of the gas chromatograph are programmably temperature controlled to operate at a volatilization temperature specific to the compound(s) sought to be separated and measured.

Grindstaff, Quirinus G. (Oak Ridge, TN)

1992-01-01T23:59:59.000Z

188

BWR Vessel and Internals Project: Quantitative Safety Assessment of BWR Reactor Internals (BWRVIP-09)  

Science Conference Proceedings (OSTI)

The Boiling Water Reactor Vessel and Internals Project (BWRVIP), formed in June, 1994, is an association of utilities focused exclusively on BWR vessel and internals issues. This BWRVIP report documents the results of a quantitative safety assessment conducted to evaluate the safety significance of failures of certain BWR internal components.

1997-02-20T23:59:59.000Z

189

Probability of Safety Valve Failure-to-Reseat Following Steam and Liquid Relief: Quantitative Expert Elicitation  

Science Conference Proceedings (OSTI)

This report describes a quantitative expert elicitation to assist in the determination of the failure probability of safety valves to reseat following steam and/or liquid relief. The expert elicitation process improves the estimation of the safety valve failure-to-reseat probability and is based on expert judgment, safety valve testing programs, and experience.

2004-08-31T23:59:59.000Z

190

Quantitative imaging of stray fields and magnetization distributions in hard magnetic element arrays  

E-Print Network (OSTI)

Quantitative imaging of stray fields and magnetization distributions in hard magnetic element with inverse magnetostatic methods. The method is applied to hard magnetic FePt and PrCo5 films which exhibit of thin hard magnetic elements. We show that by application of the MOIF technique and inverse

Johansen, Tom Henning

191

Verification of Scientific Simulations via Hypothesis-Driven Comparative and Quantitative Visualization  

Science Conference Proceedings (OSTI)

This article presents a visualization-assisted process that verifies scientific-simulation codes. Code verification is necessary because scientists require accurate predictions to interpret data confidently. This verification process integrates iterative hypothesis verification with comparative, feature, and quantitative visualization. Following this process can help identify differences in cosmological and oceanographic simulations.

Ahrens, James P [ORNL; Heitmann, Katrin [ORNL; Petersen, Mark R [ORNL; Woodring, Jonathan [Los Alamos National Laboratory (LANL); Williams, Sean [Los Alamos National Laboratory (LANL); Fasel, Patricia [Los Alamos National Laboratory (LANL); Ahrens, Christine [Los Alamos National Laboratory (LANL); Hsu, Chung-Hsing [ORNL; Geveci, Berk [ORNL

2010-11-01T23:59:59.000Z

192

BOOK REVIEWS QUANTITATIVE REMOTE SENSING OF LAND SURFACES. By S. Liang. John  

E-Print Network (OSTI)

BOOK REVIEWS QUANTITATIVE REMOTE SENSING OF LAND SURFACES. By S. Liang. John Wiley & Sons Inc-ROM. Illustrated. Price £82�50 hard- back. This new book presents the principles of optical remote sensing. The structure, content and style of the book reflect this. It has an explicit structure: it contains neat

Liang, Shunlin

193

Sources of Technical Variability in Quantitative LC-MS Proteomics: Human Brain Tissue Sample Analysis.  

SciTech Connect

To design a robust quantitative proteomics study, an understanding of both the inherent heterogeneity of the biological samples being studied as well as the technical variability of the proteomics methods and platform is needed. Additionally, accurately identifying the technical steps associated with the largest variability would provide valuable information for the improvement and design of future processing pipelines. We present an experimental strategy that allows for a detailed examination of the variability of the quantitative LC-MS proteomics measurements. By replicating analyses at different stages of processing, various technical components can be estimated and their individual contribution to technical variability can be dissected. This design can be easily adapted to other quantitative proteomics pipelines. Herein, we applied this methodology to our label-free workflow for the processing of human brain tissue. For this application, the pipeline was divided into four critical components: Tissue dissection and homogenization (extraction), protein denaturation followed by trypsin digestion and SPE clean-up (digestion), short-term run-to-run instrumental response fluctuation (instrumental variance), and long-term drift of the quantitative response of the LC-MS/MS platform over the 2 week period of continuous analysis (instrumental stability). From this analysis, we found the following contributions to variability: extraction (72%) >> instrumental variance (16%) > instrumental stability (8.4%) > digestion (3.1%). Furthermore, the stability of the platform and its’ suitability for discovery proteomics studies is demonstrated.

Piehowski, Paul D.; Petyuk, Vladislav A.; Orton, Daniel J.; Xie, Fang; Moore, Ronald J.; Ramirez Restrepo, Manuel; Engel, Anzhelika; Lieberman, Andrew P.; Albin, Roger L.; Camp, David G.; Smith, Richard D.; Myers, Amanda J.

2013-05-03T23:59:59.000Z

194

QoS-Driven Service Selection and Composition Using Quantitative Constraint Automata  

Science Conference Proceedings (OSTI)

Assuring Quality of Service (QoS) properties is critical in Service-Oriented Application (SOA) development. In this paper, we present an approach for specifying the QoS properties of services along multiple dimensions and selecting services for their ... Keywords: Composition, QoS, Quantitative Constraint Automata, Selection, Service

Sun Meng; Farhad Arbab

2009-01-01T23:59:59.000Z

195

Experiment selection for the discrimination of semi-quantitative models of dynamical systems  

Science Conference Proceedings (OSTI)

Modeling an experimental system often results in a number of alternative models that are all justified by the available experimental data. To discriminate among these models, additional experiments are needed. Existing methods for the selection of discriminatory ... Keywords: Computer-supported modeling, Information theory, Model discrimination, Population biology, Qualitative and semi-quantitative modeling and simulation

Ivayla Vatcheva; Hidde de Jong; Olivier Bernard; Nicolaas J. I. Mars

2006-04-01T23:59:59.000Z

196

High-Performance Interconnects and Computing Systems: Quantitative Studies A thesis submitted to the Department of  

E-Print Network (OSTI)

. To measure and to predict the performance of parallel computer systems, parallel benchmarks are designedHigh-Performance Interconnects and Computing Systems: Quantitative Studies By Ying Qian A thesis characteristics, parallel programming paradigms used by the applications, and the machine system's architecture

Afsahi, Ahmad

197

UPPAAL in practice: quantitative verification of a RapidIO network  

Science Conference Proceedings (OSTI)

Packet switched networks are widely used for interconnecting distributed computing platforms. RapidIO (Rapid Input/Output) is an industry standard for packet switched networks to interconnect multiple processor boards. Key performance metrics for these ... Keywords: POOSL, UPPAAL, heuristic, quantitative verification, transformation

Jiansheng Xing; Bart D. Theelen; Rom Langerak; Jaco Van De Pol; Jan Tretmans; J. P. M. Voeten

2010-10-01T23:59:59.000Z

198

Quantitative Tools for Dissection of Hydrogen-Producing Metabolic Networks-Final Report  

DOE Green Energy (OSTI)

During this project we have pioneered the development of integrated experimental-computational technologies for the quantitative dissection of metabolism in hydrogen and biofuel producing microorganisms (i.e. C. acetobutylicum and various cyanobacteria species). The application of these new methodologies resulted in many significant advances in the understanding of the metabolic networks and metabolism of these organisms, and has provided new strategies to enhance their hydrogen or biofuel producing capabilities. As an example, using mass spectrometry, isotope tracers, and quantitative flux-modeling we mapped the metabolic network structure in C. acetobutylicum. This resulted in a comprehensive and quantitative understanding of central carbon metabolism that could not have been obtained using genomic data alone. We discovered that biofuel production in this bacterium, which only occurs during stationary phase, requires a global remodeling of central metabolism (involving large changes in metabolite concentrations and fluxes) that has the effect of redirecting resources (carbon and reducing power) from biomass production into solvent production. This new holistic, quantitative understanding of metabolism is now being used as the basis for metabolic engineering strategies to improve solvent production in this bacterium. In another example, making use of newly developed technologies for monitoring hydrogen and NAD(P)H levels in vivo, we dissected the metabolic pathways for photobiological hydrogen production by cyanobacteria Cyanothece sp. This investigation led to the identification of multiple targets for improving hydrogen production. Importantly, the quantitative tools and approaches that we have developed are broadly applicable and we are now using them to investigate other important biofuel producers, such as cellulolytic bacteria.

Rabinowitz, Joshua D.; Dismukes, G.Charles.; Rabitz, Herschel A.; Amador-Noguez, Daniel

2012-10-19T23:59:59.000Z

199

Quantitative Analysis  

Science Conference Proceedings (OSTI)

Table 1   Empirical atomic sensitivity factors relative to fluorine 1 s = 1 for some instruments (a)...� 0.72 Molybdenum 1.66 2.75 1.74 1.17 � 0.73 Technetium 1.89 3.15 1.92 1.24 � 0.73 Ruthenium 2.15 3.6 2.15 1.30 � 0.73 Rhodium 2.4 4.1 2.4 1.38 � 0.74 Palladium 2.7 4.6 2.7 1.43 � 0.74 Silver 3.1 5.2 3.1 1.52 � 0.75 Cadmium 3.5 � 3.5 1.60 � 0.75 Indium 3.9 � 3.9 1.68 � 0.75 Tin 4.3 � 4.3 1.77 � 0.75...

200

Financing U.S. Renewable Energy Projects Through Public Capital Vehicles: Qualitative and Quantitative Benefits  

NLE Websites -- All DOE Office Websites (Extended Search)

Financing U.S. Renewable Financing U.S. Renewable Energy Projects Through Public Capital Vehicles: Qualitative and Quantitative Benefits Michael Mendelsohn and David Feldman Technical Report NREL/TP-6A20-58315 April 2013 NREL is a national laboratory of the U.S. Department of Energy, Office of Energy Efficiency & Renewable Energy, operated by the Alliance for Sustainable Energy, LLC. National Renewable Energy Laboratory 15013 Denver West Parkway Golden, Colorado 80401 303-275-3000 * www.nrel.gov Contract No. DE-AC36-08GO28308 Financing U.S. Renewable Energy Projects Through Public Capital Vehicles: Qualitative and Quantitative Benefits Michael Mendelsohn and David Feldman Prepared under Task No. SM13.1030

Note: This page contains sample records for the topic "quantitative trait loci" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


201

ASHRAE Standard 90.1-1999 Quantitative Analysis Worksheet | Building Energy  

NLE Websites -- All DOE Office Websites (Extended Search)

1999 Quantitative Analysis Worksheet 1999 Quantitative Analysis Worksheet This worksheet aggregates the results of building energy simulations used in support of the U.S. Department of Energy's determination regarding whether ASHRAE Standard 90.1-1999 will improve energy efficiency in commercial buildings. This determination is required by Section 304 of the Energy Conservation and Production Act. Publication Date: Monday, January 30, 2006 BECP_90_1SavingsAnalysis(050101update).xls 90_1savingsanalysis.zip Document Details Focus: Regulatory Building Type: Commercial Code Referenced: ASHRAE Standard 90.1-1999 Document type: Analysis Determination Target Audience: Federal Official State Official Contacts Web Site Policies U.S. Department of Energy USA.gov Last Updated: Tuesday, December 10, 2013 - 13:20

202

Strategic Sequencing for State Distributed PV Policies: A Quantitative Analysis of Policy Impacts and Interactions  

NLE Websites -- All DOE Office Websites (Extended Search)

Strategic Sequencing for State Strategic Sequencing for State Distributed PV Policies: A Quantitative Analysis of Policy Impacts and Interactions V.A. Krasko and E. Doris National Renewable Energy Laboratory Technical Report NREL/TP-7A30-56428 October 2012 NREL is a national laboratory of the U.S. Department of Energy, Office of Energy Efficiency & Renewable Energy, operated by the Alliance for Sustainable Energy, LLC. National Renewable Energy Laboratory 15013 Denver West Parkway Golden, Colorado 80401 303-275-3000 * www.nrel.gov Contract No. DE-AC36-08GO28308 Strategic Sequencing for State Distributed PV Policies: A Quantitative Analysis of Policy Impacts and Interactions V.A. Krasko and E. Doris National Renewable Energy Laboratory Prepared under Task No. SM12.1070

203

Quantitative, non-invasive imaging of radiation-induced DNA double strand breaks in vivo  

NLE Websites -- All DOE Office Websites (Extended Search)

Quantitative, non-invasive imaging of radiation-induced DNA double strand breaks in vivo Quantitative, non-invasive imaging of radiation-induced DNA double strand breaks in vivo Wenrong Li 1, , Fang Li 1 , Qian Huang 1 , Jingping Shen 1 , Frank Wolf 1 , Yujun He 1 , Xinjian Liu 1 , Y. Angela Hu 1 , Joel. S. Bedford 5 , and Chuan-Yuan Li 1,2,* Departments of 1 Radiation Oncology, 2 Pharmacology, University of Colorado School of Medicine, Aurora, Colorado, USA; 3 Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, USA DNA double strand breaks are a major form of DNA damage and a key mechanism through which radiotherapy and some chemotherapeutic agents kill cancer cells. Despite its importance, measuring DNA double strand breaks is still a tedious task that is normally carried out by gel electrophoresis or immunofluorescence staining. Here we report a novel approach to image and

204

Sub-0.1 nm-resolution quantitative scanning transmission electron microscopy without adjustable parameters  

Science Conference Proceedings (OSTI)

Atomic-resolution imaging in the scanning transmission electron microscope (STEM) constitutes a powerful tool for nanostructure characterization. Here, we demonstrate the quantitative interpretation of atomic-resolution high-angle annular dark-field (ADF) STEM images using an approach that does not rely on adjustable parameters. We measure independently the instrumental parameters that affect sub-0.1 nm-resolution ADF images, quantify their individual and collective contributions to the image intensity, and show that knowledge of these parameters enables a quantitative interpretation of the absolute intensity and contrast across all accessible spatial frequencies. The analysis also provides a method for the in-situ measurement of the STEM's effective source distribution.

Dwyer, C. [Monash Centre for Electron Microscopy, Monash University, Victoria 3800 (Australia); Department of Materials Engineering, Monash University, Victoria 3800 (Australia); ARC Centre of Excellence for Design in Light Metals, Monash University, Victoria 3800 (Australia); Maunders, C. [Department of Materials Engineering, Monash University, Victoria 3800 (Australia); Zheng, C. L. [Monash Centre for Electron Microscopy, Monash University, Victoria 3800 (Australia); Weyland, M.; Etheridge, J. [Monash Centre for Electron Microscopy, Monash University, Victoria 3800 (Australia); Department of Materials Engineering, Monash University, Victoria 3800 (Australia); Tiemeijer, P. C. [FEI Electron Optics, P.O. Box 80066, 5600 KA Eindhoven (Netherlands)

2012-05-07T23:59:59.000Z

205

Mixed Quantitative/Qualitative Modeling and Simulation of the Cardiovascular System  

E-Print Network (OSTI)

The cardiovascular system is composed of the hemodynamical system and the Central Nervous System (CNS) control. Whereas the structure and functioning of the hemodynamical system are well known and a number of quantitative models have already been developed that capture the behavior of the hemodynamical system fairly accurately, the CNS control is, at present, still not completely understood and no good deductive models exist that are able to describe the CNS control from physical and physiological principles. The use of qualitative methodologies may offer an interesting alternative to quantitative modeling approaches for inductively capturing the behavior of the CNS control. In this paper, a qualitative model of the CNS control of the cardiovascular system is developed by means of the Fuzzy Inductive Reasoning (FIR) methodology. Fuzzy inductive reasoning is a fairly new modeling technique that is based on the General System Problem Solving (GSPS) methodology developed by G. Klir. Prev...

Angela Nebot; François E. Cellier

1997-01-01T23:59:59.000Z

206

Quantitative Visualization of ChIP-chip Data by Using Linked Views  

SciTech Connect

Most analyses of ChIP-chip in vivo DNA binding have focused on qualitative descriptions of whether genomic regions are bound or not. There is increasing evidence, however, that factors bind in a highly overlapping manner to the same genomic regions and that it is quantitative differences in occupancy on these commonly bound regions that are the critical determinants of the different biological specificity of factors. As a result, it is critical to have a tool to facilitate the quantitative visualization of differences between transcription factors and the genomic regions they bind to understand each factor's unique roles in the network. We have developed a framework which combines several visualizations via brushing-and-linking to allow the user to interactively analyze and explore in vivo DNA binding data of multiple transcription factors. We describe these visualization types and also provide a discussion of biological examples in this paper.

Huang, Min-Yu; Weber, Gunther; Li, Xiao-Yong; Biggin, Mark; Hamann, Bernd

2010-11-05T23:59:59.000Z

207

Comparison of Qualitative (AP-913) and Quantitative (Generation Risk Assessment) Equipment Reliability Assessment Techniques  

Science Conference Proceedings (OSTI)

In the analysis of the impact of plant structures, systems and components (SSCs) on nuclear safety and plant generation, both qualitative and quantitative techniques have been employed to classify the functional importance of SSCs and to support prioritization in business decision-making. With respect to the potential impact of SSCs on plant generation, this classification has typically been accomplished via qualitative techniques that support equipment reliability programs and the implementation of INPO...

2006-12-18T23:59:59.000Z

208

Quantitative assessment of in situ microbial communities affecting nuclear waste disposal  

Science Conference Proceedings (OSTI)

Microbes in the environments surrounding nuclear waste depositories pose several questions regarding the protection of the surrounding communities. microbes can facilitate microbially influenced corrosion (MIC), mobilize and facilitate the transport of nuclides as well as produce gaseous emissions which can compromise containment. We have developed an analysis of the extant microbiota that is independent of quantitative recovery and subsequent growth, based on signature biomarkers analysis (SBA).

White, D.C. [Tennessee Univ., Knoxville, TN (United States)]|[Oak Ridge National Lab., TN (United States)

1996-05-01T23:59:59.000Z

209

Apparatus and method for quantitative assay of generic transuranic wastes from nuclear reactors  

DOE Patents (OSTI)

A combination of passive and active neutron measurements which yields quantitative information about the isotopic composition of transuranic wastes from nuclear power or weapons material manufacture reactors is described. From the measurement of prompt and delayed neutron emission and the incidence of two coincidentally emitted neutrons from induced fission of fissile material in the sample, one can quantify /sup 233/U, /sup 235/U and /sup 239/Pu isotopes in waste samples. Passive coincidence counting, including neutron multiplicity measurement and determination of the overall passive neutron flux additionally enables the separate quantitative evaluation of spontaneous fission isotopes such as /sup 240/Pu, /sup 244/Cm and /sup 252/Cf, and the spontaneous alpha particle emitter /sup 241/Am. These seven isotopes are the most important constituents of wastes from nuclear power reactors and once the mass of each isotope present is determined by the apparatus and method of the instant invention, the overall alpha particle activity can be determined to better than 1 nCi/g from known radioactivity data. Therefore, in addition to the quantitative analysis of the waste sample useful for later reclamation purposes, the alpha particle activity can be determined to decide whether permanent low-level burial is appropriate for the waste sample.

Caldwell, J.T.; Kunz, W.E.; Atencio, J.D.

1982-03-31T23:59:59.000Z

210

Apparatus and method for quantitative assay of generic transuranic wastes from nuclear reactors  

DOE Patents (OSTI)

A combination of passive and active neutron measurements which yields quantitative information about the isotopic composition of transuranic wastes from nuclear power or weapons material manufacture reactors is described. From the measurement of prompt and delayed neutron emission and the incidence of two coincidentally emitted neutrons from induced fission of fissile material in the sample, one can quantify .sup.233 U, .sup.235 U and .sup.239 Pu isotopes in waste samples. Passive coincidence counting, including neutron multiplicity measurement and determination of the overall passive neutron flux additionally enables the separate quantitative evaluation of spontaneous fission isotopes such as .sup.240 Pu, .sup.244 Cm and .sup.252 Cf, and the spontaneous alpha particle emitter .sup.241 Am. These seven isotopes are the most important constituents of wastes from nuclear power reactors and once the mass of each isotope present is determined by the apparatus and method of the instant invention, the overall alpha particle activity can be determined to better than 1 nCi/g from known radioactivity data. Therefore, in addition to the quantitative analysis of the waste sample useful for later reclamation purposes, the alpha particle activity can be determined to decide whether "permanent" low-level burial is appropriate for the waste sample.

Caldwell, John T. (Los Alamos, NM); Kunz, Walter E. (Santa Fe, NM); Atencio, James D. (Los Alamos, NM)

1984-01-01T23:59:59.000Z

211

Quantitative NDA Measurements of Advanced Reprocessing Product Materials Containing U, NP, PU, and AM  

E-Print Network (OSTI)

The ability of inspection agencies and facility operators to measure powders containing several actinides is increasingly necessary as new reprocessing techniques and fuel forms are being developed. These powders are difficult to measure with nondestructive assay (NDA) techniques because neutrons emitted from induced and spontaneous fission of different nuclides are very similar. A neutron multiplicity technique based on first principle methods was developed to measure these powders by exploiting isotope-specific nuclear properties, such as the energy-dependent fission cross sections and the neutron induced fission neutron multiplicity. This technique was tested through extensive simulations using the Monte Carlo N-Particle eXtended (MCNPX) code and by one measurement campaign using the Active Well Coincidence Counter (AWCC) and two measurement campaigns using the Epithermal Neutron Multiplicity Counter (ENMC) with various (?,n) sources and actinide materials. Four potential applications of this first principle technique have been identified: (1) quantitative measurement of uranium, neptunium, plutonium, and americium materials; (2) quantitative measurement of mixed oxide (MOX) materials; (3) quantitative measurement of uranium materials; and (4) weapons verification in arms control agreements. This technique still has several challenges which need to be overcome, the largest of these being the challenge of having high-precision active and passive measurements to produce results with acceptably small uncertainties.

Goddard, Braden

2013-05-01T23:59:59.000Z

212

Expanding the US Core CODIS Loci  

Science Conference Proceedings (OSTI)

... PowerPlex Fusion http://www.promega.com/products/pm/genetic-identity/ powerplex-fusion/ ... NIST Concordance Testing with PowerPlex Fusion ...

2012-09-27T23:59:59.000Z

213

Temperature, but Not Available Energy, Affects the Expression of a Sexually Selected Ultraviolet (UV) Colour Trait in Male European Green Lizards  

E-Print Network (OSTI)

Background: Colour signals are widely used in intraspecific communication and often linked to individual fitness. The development of some pigment-based (e.g. carotenoids) colours is often environment-dependent and costly for the signaller, however, for structural colours (e.g. ultraviolet [UV]) this topic is poorly understood, especially in terrestrial ectothermic vertebrates. Methodology/Principal Findings: In a factorial experiment, we studied how available energy and time at elevated body temperature affects the annual expression of the nuptial throat colour patch in male European green lizards (Lacerta viridis) after hibernation and before mating season. In this species, there is a female preference for males with high throat UV reflectance, and males with high UV reflectance are more likely to win fights. We found that (i) while food shortage decreased lizards ’ body condition, it did not affect colour development, and (ii) the available time for maintaining high body temperature affected the development of UV colour without affecting body condition or other colour traits. Conclusions/Significance: Our results demonstrate that the expression of a sexually selected structural colour signal depends on the time at elevated body temperature affecting physiological performance but not on available energy gained from food per se in an ectothermic vertebrate. We suggest that the effect of high ambient temperature on UV colour in male L. viridis makes it an honest signal, because success in acquiring thermally favourable territories and/or effective behavioural

Katalin Bajer; Orsolya Molnár; János Török; Gábor Herczeg

2011-01-01T23:59:59.000Z

214

Multiple-Radar Data Assimilation and Short-Range Quantitative Precipitation Forecasting of a Squall Line Observed during IHOP_2002  

Science Conference Proceedings (OSTI)

The impact of multiple–Doppler radar data assimilation on quantitative precipitation forecasting (QPF) is examined in this study. The newly developed Weather Research and Forecasting (WRF) model Advanced Research WRF (ARW) and its three-...

Qingnong Xiao; Juanzhen Sun

2007-10-01T23:59:59.000Z

215

Reliable Probabilistic Quantitative Precipitation Forecasts from a Short-Range Ensemble Forecasting System during the 2005/06 Cool Season  

Science Conference Proceedings (OSTI)

A simple binning technique developed to produce reliable probabilistic quantitative precipitation forecasts (PQPFs) from a multimodel short-range ensemble forecasting system is evaluated during the cool season of 2005/06. The technique uses ...

Nusrat Yussouf; David J. Stensrud

2008-06-01T23:59:59.000Z

216

Radar-Based Quantitative Precipitation Estimation for the Cool Season in Complex Terrain: Case Studies from the NOAA Hydrometeorology Testbed  

Science Conference Proceedings (OSTI)

This study explores error sources of the National Weather Service operational radar-based quantitative precipitation estimation (QPE) during the cool season over the complex terrain of the western United States. A new, operationally geared radar ...

Jian Zhang; Youcun Qi; David Kingsmill; Kenneth Howard

2012-12-01T23:59:59.000Z

217

Quantitative Analysis of Mt. St. Helens Ash by X-Ray Diffraction and X-Ray Fluorescence Spectrometry  

Science Conference Proceedings (OSTI)

A quantitative study by x-ray diffraction, optical polarizing microscopy, and x-ray fluorescence spectrometry of fallout and ambient ash from three Mt. St. Helens eruptions has revealed a consistent picture of the mineralogical and elemental ...

Briant L. Davis; L. Ronald Johnson; Dana T. Griffen; William Revell Phillips; Robert K. Stevens; David Maughan

1981-08-01T23:59:59.000Z

218

Pollen-Based Quantitative Reconstruction of Holocene Climate Changes in the Daihai Lake Area, Inner Mongolia, China  

Science Conference Proceedings (OSTI)

Vegetation around the Daihai Lake, northern China, is very sensitive to climate changes. In this paper, pollen-based quantitative climate reconstructions using three methods [weighted averaging partial least squares method (WAPLS), modern analog ...

Qinghai Xu; Jule Xiao; Yuecong Li; Fang Tian; Takeshi Nakagawa

2010-06-01T23:59:59.000Z

219

High Resolution Quantitative Auto-Radiography to determine microscopic distributions of B-10 in neutron capture therapy  

E-Print Network (OSTI)

The success of Boron Neutron Capture Therapy (BNCT) is heavily dependent on the microscopic distribution of B-10 in tissue. High Resolution Quantitative Auto-Radiography (HRQAR) is a potentially valuable analytical tool ...

Harris, Thomas C. (Thomas Cameron)

2006-01-01T23:59:59.000Z

220

A Review of Quantitative Precipitation Forecasts and Their Use in Short- to Medium-Range Streamflow Forecasting  

Science Conference Proceedings (OSTI)

Unknown future precipitation is the dominant source of uncertainty for many streamflow forecasts. Numerical weather prediction (NWP) models can be used to generate quantitative precipitation forecasts (QPF) to reduce this uncertainty. The ...

Lan Cuo; Thomas C. Pagano; Q. J. Wang

2011-10-01T23:59:59.000Z

Note: This page contains sample records for the topic "quantitative trait loci" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


221

Need for collection of quantitative distribution data for dosimetry and metabolic modeling  

SciTech Connect

Problems in radiation dose distribution studies in humans are discussed. Data show the effective half-times for /sup 7/Be and /sup 75/Se in the mouse, rat, monkey, dog, and human show no correlation with weight, body surface, or other readily apparent factor that could be used to equate nonhuman and human data. Another problem sometimes encountered in attempting to extrapolate animal data to humans involves equivalent doses of the radiopharmaceutical. A usual human dose for a radiopharmaceutical is 1 ml or 0.017 mg/kg. The same solution injected into a mouse in a convenient volume of 0.1 ml results in a dose of 4 ml/kg or 240 times that received by the human. The effect on whole body retention produced by a dose difference of similar magnitude for selenium in the rat shows the retention is at least twice as great with the smaller amount. With the development of methods for the collection of data throughout the body representing the fractional distribution of radioactivity versus time, not only can more realistic dose estimates be made, but also the tools will be provided for the study of physiological and biochemical interrelationships in the intact subject from which compartmental models may be made which have diagnostic significance. The unique requirement for quantitative biologic data needed for calculation of radiation absorbed doses is the same as the unique scientific contribution that nuclear medicine can make, which is the quantitative in vivo study of physiologic and biochemical processes. The technique involved is not the same as quantitation of a radionuclide image, but is a step beyond.

Lathrop, K.A.

1976-01-01T23:59:59.000Z

222

Quantitative Nanostructure Characterization Using Atomic Pair Distribution Functions Obtained From Laboratory Electron Microscopes  

Science Conference Proceedings (OSTI)

Quantitatively reliable atomic pair distribution functions (PDFs) have been obtained from nanomaterials in a straightforward way from a standard laboratory transmission electron microscope (TEM). The approach looks very promising for making electron derived PDFs (ePDFs) a routine step in the characterization of nanomaterials because of the ubiquity of such TEMs in chemistry and materials laboratories. No special attachments such as energy filters were required on the microscope. The methodology for obtaining the ePDFs is described as well as some opportunities and limitations of the method.

Abeykoon M.; Billinge S.; Malliakas, C.D.; Juhas, P.; Bozin, E.S.; Kanatzidis, M.G.

2012-05-01T23:59:59.000Z

223

Spatially resolved quantitative mapping of thermomechanical properties and phase transition temperatures using scanning probe microscopy  

DOE Patents (OSTI)

An approach for the thermomechanical characterization of phase transitions in polymeric materials (polyethyleneterephthalate) by band excitation acoustic force microscopy is developed. This methodology allows the independent measurement of resonance frequency, Q factor, and oscillation amplitude of a tip-surface contact area as a function of tip temperature, from which the thermal evolution of tip-surface spring constant and mechanical dissipation can be extracted. A heating protocol maintained a constant tip-surface contact area and constant contact force, thereby allowing for reproducible measurements and quantitative extraction of material properties including temperature dependence of indentation-based elastic and loss moduli.

Jesse, Stephen; Kalinin, Sergei V; Nikiforov, Maxim P

2013-07-09T23:59:59.000Z

224

An Evaluation of the Use of a Quantitative Image Analyzer to Determine Microhardness Values  

SciTech Connect

The use of quantitative image analyzer to determine microhardness values was investigated. Microhardness traverses were made across chemically polished, partially oxidized T-111 alloy specimens using both Vickers and Knoop indenters. Microhardness values were obtained from both area and diagonal readings using a Classimat image analyzer (Classimat is a registered trademark of E. Leitz, Inc., Rockliegh, N. J.). These values were then compared with those obtained by conventional optical measurements. The data obtained by the various methods are compared and the advantages and disadvantages such as accuracy, time requirements, versatility, and limitations of particular methods are discussed.

Teaney, P. E.; Selle, J. E.

1971-10-01T23:59:59.000Z

225

Influence of Bull Traits and Bull to Female Ratio on Reproductive Perfromance in Beef Females and of Nutrition During Gestation on Calving Difficulty in Primiparous Beef Females  

E-Print Network (OSTI)

The current study involved two experiments that were conducted at the Texas A&M AgriLife Research and Extension Center in Uvalde, TX (semi-arid environment) from 2006 to 2008. In experiment one, Bonsmara bulls ( n = 39; 20-24 mo of age) were joined with multiparous Bonsmara and Bonsmara-influenced females (n = 1013) during a 90-day breeding season in 2006, 2007, and 2008 to quantify the effects of a reduction in bull to female ratio on reproductive performance. Bulls were also placed with primiparous beef females ( n = 142). Bulls were allotted by selected physical traits, social rank, serving capacity, and seminal traits to one of two bull to female (BFR) treatments: Low (1:30-1:45; n = 10 pastures) or Conventional (1:16-1:26; n = 12 pastures) BFR. Pregnancy rate (P = 0.36), calving date (P = 0.24), and calving rate (P = 0.25) did not differ between Conventional and Low BFR treatments. The current experiment demonstrates that Low BFR can be utilized in breeding pastures of up to 2,090 ha without negatively affecting reproductive performance. In experiment two, Bonsmara heifers (3/4, 7/8, and full bloods) were exposed to Bonsmara bulls from April 15 to July 15 during each of the two years. Heifers were weighed, rectally palpated for pregnancy, and scored for BCS (1 thin - 9 fat) and frame score (1 short - 9 tall) in December (end of second trimester) during years 1 and 2. Heifers were stratified on expected calving date and randomly allotted to one of two levels of nutrition for the remainder of gestation. In year 1, heifers were allotted to range forage (n=31, low nutrition, LN) or to non-irrigated oat pasture (n=31, high nutrition, HN). In year 2, heifers were placed onto the same range environment as in year 1 (n=31, LN) or onto irrigated ryegrass pasture (n=31,HN). Heifers in the LN groups were supplemented with 20% CP cubes at the rate of 0.9 kg/heifer/day from January 2 until calving while HN heifers were not supplemented. Within 4 hr of birth, calves were weighed, and calf vigor and calving difficulty scores were recorded. Heifers were weighed within 72 hours of parturition. From treatment initiation through calving, HN heifers gained 48.6 kg whereas the LN females lost 15 kg. Twice as many HN heifers required major assistance at calving as compared to LN heifers. Calves born to the HN females weighed 3.7 kg more at birth than those born to LN females. These differences resulted in HN heifers having (P = 0.005) more calving difficulty than LN heifers (mean calving difficutly of 2.3 for HN and 1.6 for LN). The calves of the HN females were also less vigorous (P = 0.005) after birth than the calves from LN females (calf vigor score of 2.2 for HN and 3.3 for LN). Consequently, the level of nutrition during the third trimester of gestation can affect calving difficulty, calf vigor, and female weight.

Bloomberg, Blake David

2010-05-01T23:59:59.000Z

226

Revised process for work zone decision-making based on quantitative performance measures  

E-Print Network (OSTI)

Work zones create one of the most challenging environments for drivers. Implementing work zones on urban freeways creates many issues, especially with respect to mobility. Decisions made regarding the work zone should be informed by quantitative data, collected in work zones, to ensure that the mobility impacts of the work zone treatments implemented are mitigated. A new decision-making process, which addresses the shortcomings in the current decision-making processes, was developed through the course of this research. The new process incorporates a Performance Measure/Treatment matrix, which recommends multiple performance measures, each of which is chosen to measure the mobility impacts particular to a specific work zone implementation. Most importantly, the revised decision-making process incorporates a feedback loop. Quantitative data collected in work zones is analyzed after the work zone is complete, to determine the impacts specific decisions had on mobility in the work zone. The lessons learned in previous work zones are then incorporated into the decision-making process, lessening the mobility impacts of future work zones. This thesis develops the new decision-making process, and examines the issues with the application of the process.

Hartmann, Thomas Wayne

2008-08-01T23:59:59.000Z

227

Quantitative Analysis of Flow Processes in a Sand Using Synchrotron-Based X-ray Microtomography  

Science Conference Proceedings (OSTI)

Pore-scale multiphase flow experiments were developed to nondestructively visualize water flow in a sample of porous material using X-ray microtomography. The samples were exposed to similar boundary conditions as in a previous investigation, which examined the effect of initial flow rate on observed dynamic effects in the measured capillary pressure-saturation curves; a significantly higher residual saturation and higher capillary pressures were found when the sample was drained fast using a high air-phase pressure. Prior work applying the X-ray microtomography technique to pore-scale multiphase flow problems has been of a mostly qualitative nature and no experiments have been presented in the existing literature where a truly quantitative approach to investigating the multiphase flow process has been taken, including a thorough image-processing scheme. The tomographic images presented here show, both by qualitative comparison and quantitative analysis in the form of a nearest neighbor analysis, that the dynamic effects seen in previous experiments are likely due to the fast and preferential drainage of large pores in the sample. Once a continuous drained path has been established through the sample, further drainage of the remaining pores, which have been disconnected from the main flowing water continuum, is prevented.

Wildenschild, D.; Hopmans, J.W.; Rivers, M.L.; Kent, A.J.R. (OSU); (UCD); (UC)

2010-07-20T23:59:59.000Z

228

New Tool Quantitatively Maps Minority-Carrier Lifetime of Multicrystalline Silicon Bricks (Fact Sheet)  

DOE Green Energy (OSTI)

NREL's new imaging tool could provide manufacturers with insight on their processes. Scientists at the National Renewable Energy Laboratory (NREL) have used capabilities within the Process Development and Integration Laboratory (PDIL) to generate quantitative minority-carrier lifetime maps of multicrystalline silicon (mc-Si) bricks. This feat has been accomplished by using the PDIL's photoluminescence (PL) imaging system in conjunction with transient lifetime measurements obtained using a custom NREL-designed resonance-coupled photoconductive decay (RCPCD) system. PL imaging can obtain rapid high-resolution images that provide a qualitative assessment of the material lifetime-with the lifetime proportional to the pixel intensity. In contrast, the RCPCD technique provides a fast quantitative measure of the lifetime with a lower resolution and penetrates millimeters into the mc-Si brick, providing information on bulk lifetimes and material quality. This technique contrasts with commercially available minority-carrier lifetime mapping systems that use microwave conductivity measurements. Such measurements are dominated by surface recombination and lack information on the material quality within the bulk of the brick. By combining these two complementary techniques, we obtain high-resolution lifetime maps at very fast data acquisition times-attributes necessary for a production-based diagnostic tool. These bulk lifetime measurements provide manufacturers with invaluable feedback on their silicon ingot casting processes. NREL has been applying the PL images of lifetime in mc-Si bricks in collaboration with a U.S. photovoltaic industry partner through Recovery Act Funded Project ARRA T24. NREL developed a new tool to quantitatively map minority-carrier lifetime of multicrystalline silicon bricks by using photoluminescence imaging in conjunction with resonance-coupled photoconductive decay measurements. Researchers are not hindered by surface recombination and can look deeper into the material to map bulk lifetimes. The tool is being applied to silicon bricks in a project collaborating with a U.S. photovoltaic industry partner. Photovoltaic manufacturers can use the NREL tool to obtain valuable feedback on their silicon ingot casting processes.

Not Available

2011-11-01T23:59:59.000Z

229

Quantitative Cyber Risk Reduction Estimation Methodology for a Small Scada Control System  

SciTech Connect

We propose a new methodology for obtaining a quick quantitative measurement of the risk reduction achieved when a control system is modified with the intent to improve cyber security defense against external attackers. The proposed methodology employs a directed graph called a compromise graph, where the nodes represent stages of a potential attack and the edges represent the expected time-to-compromise for differing attacker skill levels. Time-to-compromise is modeled as a function of known vulnerabilities and attacker skill level. The methodology was used to calculate risk reduction estimates for a specific SCADA system and for a specific set of control system security remedial actions. Despite an 86% reduction in the total number of vulnerabilities, the estimated time-to-compromise was increased only by about 3 to 30% depending on target and attacker skill level.

Miles A. McQueen; Wayne F. Boyer; Mark A. Flynn; George A. Beitel

2006-01-01T23:59:59.000Z

230

Quantitative application of biodegradation data to environmental risk and exposure assessments  

SciTech Connect

Biodegradation is an important removal mechanism for natural and synthetic organic chemicals released to aquatic, benthic, and terrestrial ecosystems. It results in a decrease in the overall mass or load of chemicals present in the environment and is key in preventing the accumulation and persistence of chemicals in specific environmental compartments. Although biodegradation is an important process for minimizing potential adverse impacts on environmental systems, it has not been traditionally considered in a quantitative fashion in environmental risk assessments. This article outlines an approach and provides simple kinetic criteria for incorporating biodegradation rate data into environmental exposure and risk assessments. The approach is a generic one that relates biodegradation half-lives to chemical residence times in specific environmental compartments. It is broadly applicable to any organic chemical in a range of environmental compartments and has potential use as a technical and regulatory tool to better quantify environmental exposure and risk.

Larson, R.J.; Cowan, C.E. [Procter and Gamble Co., Cincinnati, OH (United States). Environmental Science Dept.

1995-08-01T23:59:59.000Z

231

Quantitative description of ion transport via plasma membrane of yeast and small cells  

E-Print Network (OSTI)

Modelling of ion transport via plasma membrane needs identification and quantitative understanding of the involved processes. Brief characterisation of ion transport systems of a yeast cell (Pma1, Ena1, TOK1, Nha1, Trk1, Trk2, non-selective cation conductance) and estimates concerning the number of molecules of each transporter per a cell allow predicting the corresponding ion flows. Comparison of ion transport in small yeast cell and several animal cell types is provided and importance of cell volume to surface ratio is stressed. Role of cell wall and lipid rafts is discussed in aspect of required increase in spatial and temporary resolution of measurements. Conclusions are formulated to describe specific features of ion transport in a yeast cell. Potential directions of future research are outlined based on the assumptions.

Vadim Volkov

2012-12-18T23:59:59.000Z

232

Full quantitative phase analysis of hydrated lime using the Rietveld method  

SciTech Connect

Full quantitative phase analysis (FQPA) using X-ray powder diffraction and Rietveld refinements is a well-established method for the characterization of various hydraulic binders such as Portland cement and hydraulic limes. In this paper, the Rietveld method is applied to hydrated lime, a non-hydraulic traditional binder. The potential presence of an amorphous phase in this material is generally ignored. Both synchrotron radiation and a conventional X-ray source were used for data collection. The applicability of the developed control file for the Rietveld refinements was investigated using samples spiked with glass. The results were cross-checked by other independent methods such as thermal and chemical analyses. The sample microstructure was observed by transmission electron microscopy. It was found that the consistency between the different methods was satisfactory, supporting the validity of FQPA for this material. For the samples studied in this work, the amount of amorphous material was in the range 2-15 wt.%.

Lassinantti Gualtieri, Magdalena, E-mail: magdalena.gualtieri@unimore.it [Dipartimento Ingegneria dei Materiali e dell'Ambiente, Universita Degli Studi di Modena e Reggio Emilia, Via Vignolese 905/a, I-41100 Modena (Italy); Romagnoli, Marcello; Miselli, Paola; Cannio, Maria [Dipartimento Ingegneria dei Materiali e dell'Ambiente, Universita Degli Studi di Modena e Reggio Emilia, Via Vignolese 905/a, I-41100 Modena (Italy)] [Dipartimento Ingegneria dei Materiali e dell'Ambiente, Universita Degli Studi di Modena e Reggio Emilia, Via Vignolese 905/a, I-41100 Modena (Italy); Gualtieri, Alessandro F. [Dipartimento di Scienze della Terra, Universita Degli Studi di Modena e Reggio Emilia, I-41100 Modena (Italy)] [Dipartimento di Scienze della Terra, Universita Degli Studi di Modena e Reggio Emilia, I-41100 Modena (Italy)

2012-09-15T23:59:59.000Z

233

Quantitative Resolution to some "Absolute Discrepancies" in Cancer Theories: a View from Phage lambda Genetic Switch  

E-Print Network (OSTI)

Is it possible to understand cancer? Or more specifically, is it possible to understand cancer from genetic side? There already many answers in literature. The most optimistic one has claimed that it is mission-possible. Duesberg and his colleagues reviewed the impressive amount of research results on cancer accumulated over 100 years. It confirms the a general opinion that considering all available experimental results and clinical observations there is no cancer theory without major difficulties, including the prevailing gene-based cancer theories. They have then listed 9 "absolute discrepancies" for such cancer theory. In this letter the quantitative evidence against one of their major reasons for dismissing mutation cancer theory, by both in vivo experiment and a first principle computation, is explicitly pointed out.

P. Ao

2007-04-03T23:59:59.000Z

234

Detection and quantitative analysis of ferrocyanide and ferricyanide: FY 93 Florida State University Raman spectroscopy report  

Science Conference Proceedings (OSTI)

This report provides a summary of work to develop and investigate the feasibility of using Raman spectroscopy with tank waste materials. It contains Raman spectra from organics, such as ethylenediaminetetraacetic acid (EDTA), hydroxyethylenediaminetetraacteic acid (HEDTA), imino diacetic acid (IDA), kerosene, tributyl phosphate (TBP), acetone and butanol, anticipated to be present in tank wastes and spectra from T-107 real and BY-104 simulant materials. The results of investigating Raman for determining moisture content in tank materials are also presented. A description of software algorithms developed to process Raman spectra from a dispersive grating spectrometer system and an in initial design for a data base to support qualitative and quantitative application of remote Raman sensing with tank wastes.

Mann, C.K.; Vickers, T.J. [Florida State Univ., Tallahassee, FL (United States). Dept. of Chemistry

1994-10-11T23:59:59.000Z

235

DanteR: an extensible R-based tool for quantitative analysis of -omics data  

Science Conference Proceedings (OSTI)

Motivation: The size and complex nature of LC-MS proteomics data sets motivates development of specialized software for statistical data analysis and exploration. We present DanteR, a graphical R package that features extensive statistical and diagnostic functions for quantitative proteomics data analysis, including normalization, imputation, hypothesis testing, interactive visualization and peptide-to-protein rollup. More importantly, users can easily extend the existing functionality by including their own algorithms under the Add-On tab. Availability: DanteR and its associated user guide are available for download at http://omics.pnl.gov/software/. For Windows, a single click automatically installs DanteR along with the R programming environment. For Linux and Mac OS X, users must first install R and then follow instructions on the DanteR web site for package installation.

Taverner, Thomas; Karpievitch, Yuliya; Polpitiya, Ashoka D.; Brown, Joseph N.; Dabney, Alan R.; Anderson, Gordon A.; Smith, Richard D.

2012-09-15T23:59:59.000Z

236

The Food Crises: A quantitative model of food prices including speculators and ethanol conversion  

E-Print Network (OSTI)

Recent increases in basic food prices are severely impacting vulnerable populations worldwide. Proposed causes such as shortages of grain due to adverse weather, increasing meat consumption in China and India, conversion of corn to ethanol in the US, and investor speculation on commodity markets lead to widely differing implications for policy. A lack of clarity about which factors are responsible reinforces policy inaction. Here, for the first time, we construct a dynamic model that quantitatively agrees with food prices. The results show that the dominant causes of price increases are investor speculation and ethanol conversion. Models that just treat supply and demand are not consistent with the actual price dynamics. The two sharp peaks in 2007/2008 and 2010/2011 are specifically due to investor speculation, while an underlying upward trend is due to increasing demand from ethanol conversion. The model includes investor trend following as well as shifting between commodities, equities and bonds to take ad...

Lagi, Marco; Bertrand, Karla Z; Bar-Yam, Yaneer

2011-01-01T23:59:59.000Z

237

Turning Qualitative into Quantitative Evidence: A Well-Used Method Made Explicit  

E-Print Network (OSTI)

#1;#2;#3;#4;#5;#4;#6;#7;#8;#2; #5;#11; #11;#5;#12; #7;#5;#4;#11;#14;#7;#8;#2; #4;#11;#5;#11; #11;#5;#12; #7;#15;#12;#5;#16; #4;#17; #18; #19;#7;#20; #21;#22;#23; #16;#7;#24; #11;#25;#14;#16;#7;#24; #16; #7;#15;#26;#27; #5;#17;#5;#11; A. W. Carus... and Sheilagh Ogilvie #24; #3;#17;#25;#7;#28;#29;#29;#30; #31;#20; #15;#7;#29;#30;!#28; #1;#2;#3;#4;#3;#2;#4;#5;#6;#4;#7;#8;#2;#3;#6; #4; #11;#3;#12;#2;#8;#3;#4; #6;#14;#15;#11;#16;#16;#11;#2;#17; Turning Qualitative into Quantitative Evidence: A Well...

Carus, A W; Ogilvie, Sheilagh

2006-03-14T23:59:59.000Z

238

White light interferometry for quantitative surface characterization in ion sputtering experiments.  

SciTech Connect

White light interferometry (WLI) can be used to obtain surface morphology information on dimensional scale of millimeters with lateral resolution as good as {approx}1 {micro}m and depth resolution down to 1 nm. By performing true three-dimensional imaging of sample surfaces, the WLI technique enables accurate quantitative characterization of the geometry of surface features and compares favorably to scanning electron and atomic force microscopies by avoiding some of their drawbacks. In this paper, results of using the WLI imaging technique to characterize the products of ion sputtering experiments are reported. With a few figures, several example applications of the WLI method are illustrated when used for (i) sputtering yield measurements and time-to-depth conversion, (ii) optimizing ion beam current density profiles, the shapes of sputtered craters, and multiple ion beam superposition and (iii) quantitative characterization of surfaces processed with ions. In particular, for sputter depth profiling experiments of {sup 25}Mg, {sup 44}Ca and {sup 53}Cr ion implants in Si (implantation energy of 1 keV per nucleon), the depth calibration of the measured depth profile curves determined by the WLI method appeared to be self-consistent with TRIM simulations for such projectile-matrix systems. In addition, high depth resolution of the WLI method is demonstrated for a case of a Genesis solar wind Si collector surface processed by gas cluster ion beam: a 12.5 nm layer was removed from the processed surface, while the transition length between the processed and untreated areas was 150 {micro}m.

Baryshev, S. V.; Zinovev, A. V.; Tripa, C. E.; Erck, R. A.; Veryovkin, I. V. (Energy Systems); ( MSD)

2012-07-01T23:59:59.000Z

239

Quantitative Ultrasonic Evaluation of Radiation-Induced Late Tissue Toxicity: Pilot Study of Breast Cancer Radiotherapy  

Science Conference Proceedings (OSTI)

Purpose: To investigate the use of advanced ultrasonic imaging to quantitatively evaluate normal-tissue toxicity in breast-cancer radiation treatment. Methods and Materials: Eighteen breast cancer patients who received radiation treatment were enrolled in an institutional review board-approved clinical study. Radiotherapy involved a radiation dose of 50.0 to 50.4 Gy delivered to the entire breast, followed by an electron boost of 10.0 to 16.0 Gy delivered to the tumor bed. Patients underwent scanning with ultrasound during follow-up, which ranged from 6 to 94 months (median, 22 months) postradiotherapy. Conventional ultrasound images and radio-frequency (RF) echo signals were acquired from treated and untreated breasts. Three ultrasound parameters, namely, skin thickness, Pearson coefficient, and spectral midband fit, were computed from RF signals to measure radiation-induced changes in dermis, hypodermis, and subcutaneous tissue, respectively. Ultrasound parameter values of the treated breast were compared with those of the untreated breast. Ultrasound findings were compared with clinical assessment using Radiation Therapy Oncology Group (RTOG) late-toxicity scores. Results: Significant changes were observed in ultrasonic parameter values of the treated vs. untreated breasts. Average skin thickness increased by 27.3%, from 2.05 {+-} 0.22mm to 2.61 {+-} 0.52mm; Pearson coefficient decreased by 31.7%, from 0.41 {+-} 0.07 to 0.28 {+-} 0.05; and midband fit increased by 94.6%, from -0.92 {+-} 7.35 dB to 0.87 {+-} 6.70 dB. Ultrasound evaluations were consistent with RTOG scores. Conclusions: Quantitative ultrasound provides a noninvasive, objective means of assessing radiation-induced changes to the skin and subcutaneous tissue. This imaging tool will become increasingly valuable as we continue to improve radiation therapy technique.

Liu Tian, E-mail: tliu34@emory.ed [Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA (United States); Zhou Jun [Department of Radiation Oncology, Columbia University Medical Center, New York, NY (United States); Yoshida, Emi J. [Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA (United States); Woodhouse, Shermian A. [Department of Radiation Oncology, Columbia University Medical Center, New York, NY (United States); Schiff, Peter B. [Department of Radiation Oncology, Emory University School of Medicine, Atlanta, GA (United States); Wang, Tony J.C. [Department of Radiation Oncology, Columbia University Medical Center, New York, NY (United States); Lu Zhengfeng; Pile-Spellman, Eliza [Department of Radiology, Columbia University Medical Center, New York, NY (United States); Zhang Pengpeng [Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, NY (United States); Kutcher, Gerald J. [Department of History, Binghamton University, Binghamton, NY (United States)

2010-11-01T23:59:59.000Z

240

Use of Quantitative Uncertainty Analysis to Support M&VDecisions in ESPCs  

SciTech Connect

Measurement and Verification (M&V) is a critical elementof an Energy Savings Performance Contract (ESPC) - without M&V, thereisno way to confirm that the projected savings in an ESPC are in factbeing realized. For any given energy conservation measure in an ESPC,there are usually several M&V choices, which will vary in terms ofmeasurement uncertainty, cost, and technical feasibility. Typically,M&V decisions are made almost solely based on engineering judgmentand experience, with little, if any, quantitative uncertainty analysis(QUA). This paper describes the results of a pilot project initiated bythe Department of Energy s Federal Energy Management Program to explorethe use of Monte-Carlo simulation to assess savings uncertainty andthereby augment the M&V decision-making process in ESPCs. The intentwas to use QUA selectively in combination with heuristic knowledge, inorder to obtain quantitative estimates of the savings uncertainty withoutthe burden of a comprehensive "bottoms-up" QUA. This approach was used toanalyze the savings uncertainty in an ESPC for a large federal agency.The QUA was seamlessly integrated into the ESPC development process andthe incremental effort was relatively small with user-friendly tools thatare commercially available. As the case study illustrates, in some casesthe QUA simply confirms intuitive or qualitative information, while inother cases, it provides insight that suggests revisiting the M&Vplan. The case study also showed that M&V decisions should beinformed by the portfolio risk diversification. By providing quantitativeuncertainty information, QUA can effectively augment the M&Vdecision-making process as well as the overall ESPC financialanalysis.

Mathew, Paul A.; Koehling, Erick; Kumar, Satish

2005-05-11T23:59:59.000Z

Note: This page contains sample records for the topic "quantitative trait loci" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


241

Formation resistivity measurements from within a cased well used to quantitatively determine the amount of oil and gas present  

DOE Patents (OSTI)

Methods to quantitatively determine the separate amounts of oil and gas in a geological formation adjacent to a cased well using measurements of formation resistivity are disclosed. The steps include obtaining resistivity measurements from within a cased well of a given formation, obtaining the porosity, obtaining the resistivity of formation water present, computing the combined amounts of oil and gas present using Archie's Equations, determining the relative amounts of oil and gas present from measurements within a cased well, and then quantitatively determining the separate amounts of oil and gas present in the formation.

Vail, III, William B. (Bothell, WA)

1997-01-01T23:59:59.000Z

242

Formation resistivity measurements from within a cased well used to quantitatively determine the amount of oil and gas present  

DOE Patents (OSTI)

Methods to quantitatively determine the separate amounts of oil and gas in a geological formation adjacent to a cased well using measurements of formation resistivity are disclosed. The steps include obtaining resistivity measurements from within a cased well of a given formation, obtaining the porosity, obtaining the resistivity of formation water present, computing the combined amounts of oil and gas present using Archie`s Equations, determining the relative amounts of oil and gas present from measurements within a cased well, and then quantitatively determining the separate amounts of oil and gas present in the formation. 7 figs.

Vail, W.B. III

1997-05-27T23:59:59.000Z

243

Apparatus and method for quantitatively evaluating total fissile and total fertile nuclide content in samples. [Patent application  

DOE Patents (OSTI)

Simultaneous photon and neutron interrogation of samples for the quantitative determination of total fissile nuclide and total fertile nuclide material present is made possible by the use of an electron accelerator. Prompt and delayed neutrons produced from resulting induced fission are counted using a single detection system and allow the resolution of the contributions from each interrogating flux leading in turn to the quantitative determination sought. Detection limits for /sup 239/Pu are estimated to be about 3 mg using prompt fission neutrons and about 6 mg using delayed neutrons.

Caldwell, J.T.; Kunz, W.E.; Cates, M.R.; Franks, L.A.

1982-07-07T23:59:59.000Z

244

Development of a Physics of Failure Model and Quantitative Assessment of the Fire Fatality Risk of Compressed Natural Gas Bus Cylinders.  

E-Print Network (OSTI)

??Title of Dissertation: DEVELOPMENT OF A PHYSICS OF FAILURE MODEL AND QUANTITATIVE ASSESSMENT OF THE FIRE FATALITY RISKS OF COMPRESSED NATURAL GAS BUS CYLINDERS The… (more)

Chamberlain, Samuel Seamore

2004-01-01T23:59:59.000Z

245

Quantitative Determination of Chemical Processes by Dynamic Nuclear Polarization Enhanced Nuclear Magnetic Resonance Spectroscopy  

E-Print Network (OSTI)

Dissolution dynamic nuclear polarization (DNP) provides several orders of magnitude of NMR signal enhancement by converting the much larger electron spin polarization to nuclear spin polarization. Polarization occurs at low temperature (1.4K) and is followed by quickly dissolving the sample for room temperature NMR detection. DNP is generally applicable to almost any small molecules and can polarize various nuclei including 1H, 19F and 13C. The large signal from DNP enhancement reduces the limit of detection to micromolar or sub-micromolar concentration in a single scan. Since DNP enhancement often provides the only source for the observable signal, it enables tracking of the polarization flow. Therefore, DNP is ideal for studying chemical processes. Here, quantitative tools are developed to separate kinetics and spin relaxation, as well as to obtain structural information from these measurements. Techniques needed for analyzing DNP polarized sample are different from those used in conventional NMR because a large, yet non-renewable hyperpolarization is available. Using small flip angle pulse excitation, the hyperpolarization can still be divided into multiple scans. Based on this principle, a scheme is presented that allows reconstruction of indirect spectral dimensions similarly to conventional 2D NMR. Additionally, small flip angle pulses can be used to obtain a succession of scans separated in time. A model describing the combined effects of the evolution of a chemical process and of spin-lattice relaxation is shown. Applied to a Diels-Alder reaction, it permitted measuring kinetics along with the effects of auto- and cross-relaxation. DNP polarization of small molecules also shows significant promise for studying protein-ligand interaction. The binding of fluorinated ligands to the protease trypsin was studied through the observation of various NMR parameter changes, such as line width, signal intensity and chemical shift of the ligands. Intermolecular polarization transfer from hyperpolarized ligand to protein can further provide information about the binding pocket of the protein. As an alternative to direct observation of protein signal, a model is presented to describe a two-step intermolecular polarization transfer between competitively binding ligands mediated through the common binding pocket of the protein. The solutions of this model relate the evolution of signal intensities to the intermolecular cross relaxation rates, which depend on individual distances in the binding epitope. In summary, DNP provides incomparable sensitivity, speed and selectivity to NMR. Quantitative models such as those discussed here enable taking full advantage of these benefits for the study of chemical processes.

Zeng, Haifeng

2012-05-01T23:59:59.000Z

246

Quantitative comparison of noise texture across CT scanners from different manufacturers  

SciTech Connect

Purpose: To quantitatively compare noise texture across computed tomography (CT) scanners from different manufacturers using the noise power spectrum (NPS). Methods: The American College of Radiology CT accreditation phantom (Gammex 464, Gammex, Inc., Middleton, WI) was imaged on two scanners: Discovery CT 750HD (GE Healthcare, Waukesha, WI), and SOMATOM Definition Flash (Siemens Healthcare, Germany), using a consistent acquisition protocol (120 kVp, 0.625/0.6 mm slice thickness, 250 mAs, and 22 cm field of view). Images were reconstructed using filtered backprojection and a wide selection of reconstruction kernels. For each image set, the 2D NPS were estimated from the uniform section of the phantom. The 2D spectra were normalized by their integral value, radially averaged, and filtered by the human visual response function. A systematic kernel-by-kernel comparison across manufacturers was performed by computing the root mean square difference (RMSD) and the peak frequency difference (PFD) between the NPS from different kernels. GE and Siemens kernels were compared and kernel pairs that minimized the RMSD and |PFD| were identified. Results: The RMSD (|PFD|) values between the NPS of GE and Siemens kernels varied from 0.01 mm{sup 2} (0.002 mm{sup -1}) to 0.29 mm{sup 2} (0.74 mm{sup -1}). The GE kernels 'Soft,''Standard,''Chest,' and 'Lung' closely matched the Siemens kernels 'B35f,''B43f,''B41f,' and 'B80f' (RMSD < 0.05 mm{sup 2}, |PFD| < 0.02 mm{sup -1}, respectively). The GE 'Bone,''Bone+,' and 'Edge' kernels all matched most closely with Siemens 'B75f' kernel but with sizeable RMSD and |PFD| values up to 0.18 mm{sup 2} and 0.41 mm{sup -1}, respectively. These sizeable RMSD and |PFD| values corresponded to visually perceivable differences in the noise texture of the images. Conclusions: It is possible to use the NPS to quantitatively compare noise texture across CT systems. The degree to which similar texture across scanners could be achieved varies and is limited by the kernels available on each scanner.

Solomon, Justin B.; Christianson, Olav; Samei, Ehsan [Carl E. Ravin Advanced Imaging Laboratories and Clinical Imaging Physics Group, Department of Radiology, Medical Physics Graduate Program, Duke University Medical Center, Durham, North Carolina 27705 (United States); Carl E. Ravin Advanced Imaging Laboratories and Clinical Imaging Physics Group, Department of Radiology, Duke University Medical Center, Durham, North Carolina 27705 (United States); Carl E. Ravin Advanced Imaging Laboratories and Clinical Imaging Physics Group, Medical Physics Graduate Program, Departments of Radiology, Physics, Biomedical Engineering, and Electrical and Computer Engineering, Duke University, Durham, North Carolina 27705 (United States)

2012-10-15T23:59:59.000Z

247

On the Performance of a Low-Cost K-Band Doppler Radar for Quantitative Rain Measurements  

Science Conference Proceedings (OSTI)

This paper deals with the ability of a vertically pointing, FM–CW Doppler radar to measure quantitatively raindrop size distributions and rainfall intensity. The wavelength of the radar is 12.5 mm (K band). To improve estimates of the rainfall ...

Martin Löffler-Mang; Michael Kunz; Willi Schmid

1999-03-01T23:59:59.000Z

248

Quantitative measurement of atomic sodium in the plume of a single burning coal particle  

Science Conference Proceedings (OSTI)

The release of volatile sodium during coal combustion is a significant factor in the fouling and corrosion of heat transfer surfaces within industrial coal-fired boilers. A method for measuring the temporal release of atomic sodium from a single coal particle is described. Laser absorption was used to calibrate laser-induced fluorescence measurements of atomic sodium utilising the sodium D1 line (589.59 nm) in a purpose-designed flat flame environment. The calibration was then applied to planar laser-induced fluorescence measurements of sodium atoms in the plume from a single Victorian brown coal particle (53 mg) suspended within the flat flame. The peak concentration of atomic sodium was approximately 64.1 ppb after 1080.5 s, which appears to correspond to the end of char combustion. To our knowledge this is the first in situ quantitative measurement of the concentration field of atomic sodium in the plume above a burning particle. A simple kinetic model has been used to estimate the rate of sodium decay in the post-flame gases. Comparison of the estimated and measured decay rates showed reasonable agreement. (author)

van Eyk, P.J.; Ashman, P.J.; Alwahabi, Z.T. [Cooperative Research Centre for Clean Power from Lignite, School of Chemical Engineering, The University of Adelaide, South Australia 5005 (Australia); Nathan, G.J. [School of Mechanical Engineering, The University of Adelaide, South Australia 5005 (Australia)

2008-11-15T23:59:59.000Z

249

Development of simple quantitative test for lack of field emission orthodoxy  

E-Print Network (OSTI)

This paper describes a simple quantitative test applicable to current-voltage data for cold field electron emission (CFE). It can decide whether individual reported field-enhancement-factor (FEF) values are spuriously large. The paper defines an "orthodox emission situation" by a set of ideal experimental, physical and mathematical conditions, and shows how (in these conditions) operating values of scaled barrier field (f) can be extracted from Fowler-Nordheim (FN) and Millikan-Lauritsen (ML) plots. By analyzing historical CFE experiments, which are expected to nearly satisfy the orthodoxy conditions, "apparently reasonable" and "clearly unreasonable" experimental ranges for f are found. These provide a test for lack of orthodoxy. For illustration, this test is applied to 17 post-1975 CFE data sets, mainly for carbon and semiconductor nanostructures. Some extracted f-value ranges are apparently reasonable (including many carbon results), some are clearly unreasonable. It is shown that this test applies to any field-emission diode geometry and any form of FN or ML plot. It is proved mathematically that, if the extracted f-value range is "unreasonably high", then FEF-values extracted by the usual literature method are spuriously large. Probably, all new field-emitter materials should be tested in this way. Appropriate data-analysis theory needs developing for non-orthodox emitters.

Richard G. Forbes

2012-09-28T23:59:59.000Z

250

Quantitative evaluation of air-filtration systems in use at asbestos abatement sites: Research in progress  

Science Conference Proceedings (OSTI)

High Efficiency Particulate Air (HEPA) filtration systems serve as the principal engineering control to remove asbestos particulate from airstreams at abatement projects. However, little quantitative information is available on the integrity of these air-filtration systems in preventing asbestos fiber release into outdoor air or adjacent building areas, potentially exposing occupants. A study is in progress to assess the performance of HEPA filtration systems in use at asbestos abatement projects to determine each systems operating particle-removal efficiency, percent concentration, and decontamination factor. The asbestos-fiber concentration in the inlet and discharge air of each filtration system will be determined by isokinetic air sampling. Each isokinetic air sample collected will be analyzed using transmission electron microscopy. In addition, in-place aerosol performance testing will be conducted according to procedures outlined in ANSI/ASME N510-1980. The test method utilizes a polydispersed dioctyl phthalate aerosol (generated by Laskin nozzles) and a photometric light-scattering mass-concentration detector as the measuring device.

Powers, T.J.; Cain, W.C.; Wilmoth, R.C.; Kominsky, J.R.; Brownlee, J.A.

1989-01-01T23:59:59.000Z

251

DT 03/2002Unifying Quantitative and Qualitative Analyses in Management  

E-Print Network (OSTI)

This paper addresses the issue of combining qualitative and quantitative methodologies in management and organization research. It reviews the extant literature, and applies such combined methodology in a research project on vertical strategic alliances, conducted within a just in time manufacturing environment in North America, in 2001. While the major positive and negative aspects are highlighted, I conclude that the successful implementation of this dual method enables a more thorough and robust set of conclusions. Resumen El tema principal abordado en este trabajo es la metodología combinada cuantitativa y cualitativa en la investigación sobre la organización y el management de la empresa. En el trabajo se hace una extensa revisión de la literatura y se aplica tal metodología combinada a un proyecto de investigación sobre alianzas estratégicas, realizado en Estados Unidos en el año 2001. Si bien se destacan los principales aspectos positivos y negativos de una y otra metodología, concluyo que la implementación exitosa de este método dual permite establecer conclusiones más rigurosas y robustas.

Luiz F. Mesquita; Luiz F. Mesquita

2002-01-01T23:59:59.000Z

252

ANSI/ASHRAE/IESNA Standard 90.1-2007 Final Determination Quantitative Analysis  

SciTech Connect

The United States (U.S.) Department of Energy (DOE) conducted a final quantitative analysis to assess whether buildings constructed according to the requirements of the American National Standards Institute (ANSI)/American Society of Heating, Refrigerating and Air-Conditioning Engineers (ASHRAE)/Illuminating Engineering Society of North America (IESNA) Standard 90.1-2007 would result in energy savings compared with buildings constructed to ANSI/ASHRAE/IESNA Standard 90.1-2004. The final analysis considered each of the 44 addenda to ANSI/ASHRAE/IESNA Standard 90.1-2004 that were included in ANSI/ASHRAE/IESNA Standard 90.1-2007. All 44 addenda processed by ASHRAE in the creation of Standard 90.1-2007 from Standard 90.1-2004 were reviewed by DOE, and their combined impact on a suite of 15 building prototype models in 15 ASHRAE climate zones was considered. Most addenda were deemed to have little quantifiable impact on building efficiency for the purpose of DOE’s final determination. However, out of the 44 addenda, 9 were preliminarily determined to have measureable and quantifiable impact.

Halverson, Mark A.; Liu, Bing; Richman, Eric E.; Winiarski, David W.

2011-05-01T23:59:59.000Z

253

ANSI/ASHRAE/IESNA Standard 90.1-2010 Preliminary Determination Quantitative Analysis  

SciTech Connect

The United States (U.S.) Department of Energy (DOE) conducted a preliminary quantitative analysis to assess whether buildings constructed according to the requirements of the American National Standards Institute (ANSI)/American Society of Heating, Refrigerating and Air-Conditioning Engineers (ASHRAE)/Illuminating Engineering Society of North America (IESNA) Standard 90.1-2010 (ASHRAE Standard 90.1-2010, Standard 90.1-2010, or 2010 edition) would result in energy savings compared with buildings constructed to ANSI/ASHRAE/IESNA Standard 90.1-2007(ASHRAE Standard 90.1-2007, Standard 90.1-2007, or 2007 edition). The preliminary analysis considered each of the 109 addenda to ASHRAE Standard 90.1-2007 that were included in ASHRAE Standard 90.1-2010. All 109 addenda processed by ASHRAE in the creation of Standard 90.1-2010 from Standard 90.1-2007 were reviewed by DOE, and their combined impact on a suite of 16 building prototype models in 15 ASHRAE climate zones was considered. Most addenda were deemed to have little quantifiable impact on building efficiency for the purpose of DOE’s preliminary determination. However, out of the 109 addenda, 34 were preliminarily determined to have measureable and quantifiable impact.

Halverson, Mark A.; Liu, Bing; Rosenberg, Michael I.

2010-11-01T23:59:59.000Z

254

Quantitative characterizations of phasic structure developments by local measurement methods in two-phase flow  

SciTech Connect

An experimental study on the internal structure an a out in a 25.4 mm ID pipe. The local void fraction and interfacial area concentration were measured by a double-sensor probe. The flow structure development was visualized by measuring the radial distribution of these two parameters at three axial, locations (L/D = 12, 62, and 112). A more detailed study on the fully developed flow structure was conducted at L/D = 120. The interfacial structure were measured by the double- and four-sensor probes. A bubbly to-=slug transition region was defined according to the local data.The area-averaged void fraction measurements were given by a gamma densitometer. Other parameters such as the Taylor bubble film thickness, bubble length and slug unit length in slug flow were measured by a film robe. The redundant measurements were made to calibrate the local probe measurements. The quantitative representation of the phasic structure can then be used for modeling.

Eberle, C.S. [Argonne National Lab., IL (United States); Leung, W.H.; Wu, Q.; Ueno, T.; Ishii, M. [Purdue Univ., Lafayette, IN (United States). School of Nuclear Engineering

1995-06-01T23:59:59.000Z

255

Quantitative analysis of intra-Golgi transport reveals inter-cisternal exchange for all cargo  

E-Print Network (OSTI)

The mechanisms controlling the transport of proteins across the Golgi stack of mammalian and plant cells is the subject of intense debate, with two models, cisternal progression and inter-cisternal exchange, emerging as major contenders. A variety of transport experiments have claimed support for each of these models. We reevaluate these experiments using a single quantitative coarse-grained framework of intra-Golgi transport that accounts for both transport models and their many variants. Our analysis makes a definitive case for the existence of inter-cisternal exchange both for small membrane proteins (VSVG) and large protein complexes (procollagen) -- this implies that membrane structures larger than the typical protein-coated vesicles must be involved in transport. Notwithstanding, we find that current observations on protein transport cannot rule out cisternal progression as contributing significantly to the transport process. To discriminate between the different models of intra-Golgi transport, we suggest experiments and an analysis based on our extended theoretical framework that compare the dynamics of transiting and resident proteins.

Serge Dmitrieff; Madan Rao; Pierre Sens

2013-07-26T23:59:59.000Z

256

Quantitative autoradiography of muscarinic and benzodiazepine receptors in the forebrain of the turtle, Pseudemys scripta  

SciTech Connect

The distribution of muscarinic and benzodiazepine receptors was investigated in the turtle forebrain by the technique of in vitro receptor autoradiography. Muscarinic binding sites were labeled with 1 nM /sup 3/H-quinuclidinyl benzilate (/sup 3/H-QNB), and benzodiazepine sites were demonstrated with the aid of 1 nM /sup 3/H-flunitrazepam (/sup 3/H-FLU). Autoradiograms generated on /sup 3/H-Ultrofilm apposed to tissue slices revealed regionally specific distributions of muscarinic and benzodiazepine binding sites that are comparable with those for mammalian brain. Dense benzodiazepine binding was found in the anterior olfactory nucleus, the lateral and dorsal cortices, and the dorsal ventricular ridge (DVR), a structure with no clear mammalian homologue. Muscarinic binding sites were most dense in the striatum, accumbens, DVR, lateral geniculate, and the anterior olfactory nucleus. Cortical binding sites were studied in greater detail by quantitative analysis of autoradiograms generated by using emulsion-coated coverslips. Laminar gradients of binding were observed that were specific for each radioligand; /sup 3/H-QNB sites were most dense in the inner molecular layer in all cortical regions, whereas /sup 3/H-FLU binding was generally most concentrated in the outer molecular layer and was least dense through all layers in the dorsomedial cortex. Because pyramidal cells are arranged in register in turtle cortex, the laminar patterns of receptor binding may reflect different receptor density gradients along pyramidal cell dendrites.

Schlegel, J.R.; Kriegstein, A.R.

1987-11-22T23:59:59.000Z

257

Highly Quantitative Electrochemical Characterization of Non-Aqueous Electrolytes & Solid Electrolyte Interphases  

DOE Green Energy (OSTI)

The methods to measure solid electrolyte interphase (SEI) electrochemical properties and SEI formation capability of non-aqueous electrolyte solutions are not adequately addressed in the literature. And yet, there is a strong demand in new electrolyte generations that promote stabilized SEIs and have an influence to resolve safety, calendar life and other limitations of Li-ion batteries. To fill this gap, in situ electrochemical approach with new descriptive criteria for highly quantitative characterization of SEI and electrolytes is proposed. These criteria are: SEI formation capacity, SEI corrosion rate, SEI maintenance rate, and SEI kinetic stability. These criteria are associated with battery parameters like irreversible capacity, self-discharge, shelf-life, power, etc. Therefore, they are especially useful for electrolyte development and standard fast screening, allowing a skillful approach to narrow down the search for the best electrolyte. The characterization protocol also allows retrieving information on interfacial resistance for SEI layers and the electrochemical window of electrolytes, the other important metrics of characterization. The method validation was done on electrolyte blends containing phosphazenes, developed at Idaho National Laboratory, as 1.2M LiPF6 [80 % EC-MEC (2:8) (v/v) + 20% Phosphazene variety] (v/v), which were targeted for safer electrolyte variations.

Sergiy V. Sazhin; Kevin L. Gering; Mason K. Harrup; Harry W. Rollins

2012-10-01T23:59:59.000Z

258

Quantitative assessment of medical waste generation in the capital city of Bangladesh  

Science Conference Proceedings (OSTI)

There is a concern that mismanagement of medical waste in developing countries may be a significant risk factor for disease transmission. Quantitative estimation of medical waste generation is needed to estimate the potential risk and as a basis for any waste management plan. Dhaka City, the capital of Bangladesh, is an example of a major city in a developing country where there has been no rigorous estimation of medical waste generation based upon a thorough scientific study. These estimates were obtained by stringent weighing of waste in a carefully chosen, representative, sample of HCEs, including non-residential diagnostic centres. This study used a statistically designed sampling of waste generation in a broad range of Health Care Establishments (HCEs) to indicate that the amount of waste produced in Dhaka can be estimated to be 37 {+-} 5 ton per day. The proportion of this waste that would be classified as hazardous waste by World Health Organisation (WHO) guidelines was found to be approximately 21%. The amount of waste, and the proportion of hazardous waste, was found to vary significantly with the size and type of HCE.

Patwary, Masum A. [School of Science and Technology, University of Teesside, Middlesbrough, TS1 3BA (United Kingdom)], E-mail: M.patwary@tees.ac.uk; O'Hare, William Thomas [School of Science and Technology, University of Teesside, Middlesbrough, TS1 3BA (United Kingdom)], E-mail: w.t.ohare@tees.ac.uk; Street, Graham [School of Science and Technology, University of Teesside, Middlesbrough, TS1 3BA (United Kingdom)], E-mail: grahamandlinda@talktalk.net; Maudood Elahi, K. [Stamford University Bangladesh, Dhaka 1209 (Bangladesh)], E-mail: elahikm@yahoo.com; Hossain, Syed Shahadat [Institute of Statistical Research and Training (ISRT), University of Dhaka, Dhaka 1000 (Bangladesh)], E-mail: shahadat@isrt.ac.bd; Sarker, Mosharraf H. [School of Science and Technology, University of Teesside, Middlesbrough, TS1 3BA (United Kingdom)], E-mail: m.sarker@tees.ac.uk

2009-08-15T23:59:59.000Z

259

Quantitative method for measuring heat flux emitted from a cryogenic object  

DOE Patents (OSTI)

The present invention is a quantitative method for measuring the total heat flux, and of deriving the total power dissipation, of a heat-fluxing object which includes the steps of placing an electrical noise-emitting heat-fluxing object in a liquid helium bath and measuring the superfluid transition temperature of the bath. The temperature of the liquid helium bath is thereafter reduced until some measurable parameter, such as the electrical noise, exhibited by the heat-fluxing object or a temperature-dependent resistive thin film in intimate contact with the heat-fluxing object, becomes greatly reduced. The temperature of the liquid helum bath is measured at this point. The difference between the superfluid transition temperature of the liquid helium bath surrounding the heat-fluxing object, and the temperature of the liquid helium bath when the electrical noise emitted by the heat-fluxing object becomes greatly reduced, is determined. The total heat flux from the heat-fluxing object is determined as a function of this difference between these temperatures. In certain applications, the technique can be used to optimize thermal design parameters of cryogenic electronics, for example, Josephson junction and infrared sensing devices.

Duncan, R.V.

1993-03-16T23:59:59.000Z

260

Quantitative Phosphoproteomics Identifies Filaggrin and other Targets of Ionizing Radiation in a Human Skin Model  

Science Conference Proceedings (OSTI)

Our objective here was to perform a quantitative phosphoproteomic study on a reconstituted human skin tissue to identify low and high dose ionizing radiation dependent signaling in a complex 3-dimensional setting. Application of an isobaric labeling strategy using sham and 3 radiation doses (3, 10, 200 cGy) resulted in the identification of 1113 unique phosphopeptides. Statistical analyses identified 151 phosphopeptides showing significant changes in response to radiation and radiation dose. Proteins responsible for maintaining skin structural integrity including keratins and desmosomal proteins (desmoglein, desmoplakin, plakophilin 1 and 2,) had altered phosphorylation levels following exposure to both low and high doses of radiation. A phosphorylation site present in multiple copies in the linker regions of human profilaggrin underwent the largest fold change. Increased phosphorylation of these sites coincided with altered profilaggrin processing suggesting a role for linker phosphorylation in human profilaggrin regulation. These studies demonstrate that the reconstituted human skin system undergoes a coordinated response to ionizing radiation involving multiple layers of the stratified epithelium that serve to maintain skin barrier functions and minimize the damaging consequences of radiation exposure.

Yang, Feng; Waters, Katrina M.; Webb-Robertson, Bobbie-Jo M.; Sowa, Marianne B.; Freiin von Neubeck, Claere H.; Aldrich, Joshua T.; Markillie, Lye Meng; Wirgau, Rachel M.; Gristenko, Marina A.; Zhao, Rui; Camp, David G.; Smith, Richard D.; Stenoien, David L.

2012-04-17T23:59:59.000Z

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261

Quantitative autoradiography of TRH receptors and radioimmunoassay of TRH in the cat central nervous system  

SciTech Connect

In the cat, microinjection of Thyrotropin-Releasing Hormone (TRH) into certain areas of the central nervous system (CNS) changes ventilation and cardiovascular variables. To initiate a more systematic investigation of these effects, they undertook a study to determine the location of TRH and its receptors in the cat CNS. Using techniques previously described from the laboratory, quantitative autoradiograms for TRH receptors of the cat brain were produced; additional specimens were dissected, and radioimmunoassay for TRH was performed. Heterogeneous distribution of receptors was observed in the cat brain. In the forebrain, large quantities of TRH receptors were found in amygdala, hippocampus, claustrum, pyriform nucleus, and tuberculum olfactorium. In the brainstem, high concentrations were localized to the dorsal motor nucleus of the vagus, the hypoglossal nucleus, and the periaqueductal grey. The cerebellum contained few receptors. The largest quantities of the TRH tripeptide were noted in the hypothalamus and septum, with substantial amounts also obtained from the olfactory bulb, corpus striatum, and thalamus. The results demonstrate that the distribution of TRH and TRH receptors in the cat brain is very similar to that previously described in the rat and human brain. They provide a basis for exploring the physiological and pharmacological effects of TRH in cats.

Bogin, R.M.; Kreider, M.S.; Caine, S.B.; Pack, A.I.; Winokur, A.

1986-03-05T23:59:59.000Z

262

QUANTITATIVE REAL-TIME PCR DETECTION OF PERKINSUS MARINUS AND HAPLOSPORIDIUM NELSONI IN TEXAS OYSTERS  

E-Print Network (OSTI)

Haplosporidium nelsoni (MSX) and Perkinsus marinus (Dermo) are protozoan parasites that are traditionally detected using time and labor intensive histological methods. Recently developed traditional PCR assays, specific for these parasites, were used to for initial screening of presence/absence in samples of the eastern oyster, Crassostrea virginica, collected from Galveston Bay, Aransas Bay, and Corpus Christi Bay, Texas. H. nelsoni (MSX) was not detected in any of the samples. P. marinus (dermo) was detected in oysters from all bays. Oysters that tested positive for P. marinus were further screened with quantitative PCR assays to enumerate the parasites. These data were directly compared to values obtained by Ray’s Fluid Thioglycollate histological method from the same sample. Though these tests have not been “ground-truthed” against the traditional histological methods it is the goal of this project to begin the process of comparing the two methods. There was strong agreement between the PCR and histological determination of P. marinus that is promising for eventual transition to PCR assays.

Heare, Jake Emerson

2011-08-04T23:59:59.000Z

263

Improved Quantitative Analysis of Ion Mobility Spectrometry by Chemometric Multivariate Calibration  

Science Conference Proceedings (OSTI)

Traditional peak-area calibration and the multivariate calibration methods of principle component regression (PCR) and partial least squares (PLS), including unfolded PLS (U-PLS) and multi-way PLS (N-PLS), were evaluated for the quantification of 2,4,6-trinitrotoluene (TNT) and cyclo-1,3,5-trimethylene-2,4,6-trinitramine (RDX) in Composition B samples analyzed by temperature step desorption ion mobility spectrometry (TSD-IMS). The true TNT and RDX concentrations of eight Composition B samples were determined by high performance liquid chromatography with UV absorbance detection. Most of the Composition B samples were found to have distinct TNT and RDX concentrations. Applying PCR and PLS on the exact same IMS spectra used for the peak-area study improved quantitative accuracy and precision approximately 3 to 5 fold and 2 to 4 fold, respectively. This in turn improved the probability of correctly identifying Composition B samples based upon the estimated RDX and TNT concentrations from 11% with peak area to 44% and 89% with PLS. This improvement increases the potential of obtaining forensic information from IMS analyzers by providing some ability to differentiate or match Composition B samples based on their TNT and RDX concentrations.

Fraga, Carlos G.; Kerr, Dayle; Atkinson, David A.

2009-09-01T23:59:59.000Z

264

Quantitative method for measuring heat flux emitted from a cryogenic object  

DOE Patents (OSTI)

The present invention is a quantitative method for measuring the total heat flux, and of deriving the total power dissipation, of a heat-fluxing object which includes the steps of placing an electrical noise-emitting heat-fluxing object in a liquid helium bath and measuring the superfluid transition temperature of the bath. The temperature of the liquid helium bath is thereafter reduced until some measurable parameter, such as the electrical noise, exhibited by the heat-fluxing object or a temperature-dependent resistive thin film in intimate contact with the heat-fluxing object, becomes greatly reduced. The temperature of the liquid helum bath is measured at this point. The difference between the superfluid transition temperature of the liquid helium bath surrounding the heat-fluxing object, and the temperature of the liquid helium bath when the electrical noise emitted by the heat-fluxing object becomes greatly reduced, is determined. The total heat flux from the heat-fluxing object is determined as a function of this difference between these temperatures. In certain applications, the technique can be used to optimize thermal design parameters of cryogenic electronics, for example, Josephson junction and infra-red sensing devices.

Duncan, Robert V. (Tijeras, NM)

1993-01-01T23:59:59.000Z

265

Characterization of geometrical factors for quantitative angle-resolved photoelectron spectroscopy  

SciTech Connect

For conventional angle-resolved x-ray photoelectron spectroscopy (ARXPS), the area under the core-level peaks depends mainly on the in-depth distribution of chemical species at the top surface of a specimen. But the x-ray photoelectron spectroscopy (XPS) intensity is also affected by tool-related geometrical factors such as the shape of the x-ray beam, the spectrometer analysis volume, and the manipulator rotation axis. Data analysis is therefore typically based on normalization with respect to the signal from the substrate. Here, we present an original method to perform quantitative ARXPS without normalization, involving evaluation of these geometrical factors. The method is illustrated for a multiprobe XPS system using a methodology based on a specific software (XPSGeometry{sup Registered-Sign }), but is a general process that can be adapted to all types of XPS equipment, even those not specifically designed for ARXPS. In that case, this method enables bringing the sample as close as possible to the manipulator axis of rotation in order to perform automatic acquisitions.

Martinez, Eugenie; Herrera-Gomez, Alberto; Allain, Mickael; Renault, Olivier; Faure, Alain; Chabli, Amal; Bertin, Francois [CEA, LETI, MINATEC Campus, 17 rue des Martyrs, F-38054 Grenoble Cedex 9 (France); CINVESTAV-Queretaro, Libramiento Norponiente 2000, Real de Juriquilla, Queretaro, 76000 (Mexico); CEA, LETI, MINATEC Campus, 17 rue des Martyrs, F-38054 Grenoble Cedex 9 (France)

2012-07-15T23:59:59.000Z

266

ANSI/ASHRAE/IES Standard 90.1-2010 Final Determination Quantitative Analysis  

SciTech Connect

The U.S. Department of Energy (DOE) conducted a final quantitative analysis to assess whether buildings constructed according to the requirements of the American National Standards Institute (ANSI)/American Society of Heating, Refrigerating and Air-Conditioning Engineers (ASHRAE)/Illuminating Engineering Society of North America (IESNA) Standard 90.1-2010 (ASHRAE Standard 90.1-2010, Standard 90.1-2010, or 2010 edition) would result in energy savings compared with buildings constructed to ANSI/ASHRAE/IESNA Standard 90.1-2007(ASHRAE Standard 90.1-2007, Standard 90.1-2007, or 2007 edition). The final analysis considered each of the 109 addenda to ASHRAE Standard 90.1-2007 that were included in ASHRAE Standard 90.1-2010. All 109 addenda processed by ASHRAE in the creation of Standard 90.1-2010 from Standard 90.1-2007 were reviewed by DOE, and their combined impact on a suite of 16 building prototype models in 15 ASHRAE climate zones was considered. Most addenda were deemed to have little quantifiable impact on building efficiency for the purpose of DOE's final determination. However, out of the 109 addenda, 34 were preliminarily determined to have a measureable and quantifiable impact. A suite of 240 computer energy simulations for building prototypes complying with ASHRAE 90.1-2007 was developed. These prototypes were then modified in accordance with these 34 addenda to create a second suite of corresponding building simulations reflecting the same buildings compliant with Standard 90.1-2010. The building simulations were conducted using the DOE EnergyPlus building simulation software. The resulting energy use from the complete suite of 480 simulation runs was then converted to energy use intensity (EUI, or energy use per unit floor area) metrics (Site EUI, Primary EUI, and energy cost intensity [ECI]) results for each simulation. For each edition of the standard, these EUIs were then aggregated to a national basis for each prototype using weighting factors based on construction floor area developed for each of the 15 U.S. climate zones using commercial construction data. When compared, the resulting weighted EUIs indicated that each of the 16 building prototypes used less energy under Standard 90.1-2010 than under Standard 90.1-2007 on a national basis when considering site energy, primary energy, or energy cost. The EUIs were also aggregated across building types to a national commercial building basis using the same weighting data. On a national basis, the final quantitative analysis estimated a floor-space-weighted national average reduction in new building energy consumption of 18.2 percent for source energy and 18.5 percent when considering site energy. An 18.2 percent savings in energy cost, based on national average commercial energy costs for electricity and natural gas, was also estimated.

Halverson, Mark A.; Rosenberg, Michael I.; Liu, Bing

2011-10-31T23:59:59.000Z

267

Lung Density Changes After Stereotactic Radiotherapy: A Quantitative Analysis in 50 Patients  

Science Conference Proceedings (OSTI)

Purpose: Radiologic lung density changes are observed in more than 50% of patients after stereotactic body radiotherapy (SBRT) for lung cancer. We studied the relationship between SBRT dose and posttreatment computed tomography (CT) density changes, a surrogate for lung injury. Methods and Materials: The SBRT fractionation schemes used to treat Stage I lung cancer with RapidArc were three fractions of 18 Gy, five fractions of 11 Gy, or eight fractions of 7.5 Gy, prescribed at the 80% isodose. Follow-up CT scans performed at less than 6 months (n = 50) and between 6 and 9 months (n = 30) after SBRT were reviewed. Posttreatment scans were coregistered with baseline scans using a B-spline deformable registration algorithm. Voxel-Hounsfield unit histograms were created for doses between 0.5 and 50 Gy. Linear mixed effects models were used to assess the effects of SBRT dose on CT density, and the influence of possible confounders was tested. Results: Increased CT density was associated with higher dose, increasing planning target volume size, and increasing time after SBRT (all p 6 Gy, were most prominent in areas receiving >20 Gy, and seemed to plateau above 40 Gy. In regions receiving >36 Gy, the reduction in air-filled fraction of lung after treatment was up to 18%. No increase in CT density was observed in the contralateral lung receiving {>=}3 Gy. Conclusions: A dose-response relationship exists for quantitative CT density changes after SBRT. A threshold of effect is seen at low doses, and a plateau at highest doses.

Palma, David A., E-mail: david.palma@uwo.ca [Department of Radiation Oncology, VU University Medical Center, Amsterdam (Netherlands); Soernsen de Koste, John van; Verbakel, Wilko F.A.R. [Department of Radiation Oncology, VU University Medical Center, Amsterdam (Netherlands); Vincent, Andrew [Department of Biometrics, Netherlands Cancer Institute, Amsterdam (Netherlands); Senan, Suresh [Department of Radiation Oncology, VU University Medical Center, Amsterdam (Netherlands)

2011-11-15T23:59:59.000Z

268

Formation resistivity measurements from within a cased well used to quantitatively determine the amount of oil and gas present  

DOE Patents (OSTI)

Methods to quantitatively determine the separate amounts of oil and gas in a geological formation adjacent to a cased well using measurements of formation resistivity. The steps include obtaining resistivity measurements from within a cased well of a given formation, obtaining the porosity, obtaining the resistivity of formation water present, computing the combined amounts of oil and gas present using Archie's Equations, determining the relative amounts of oil and gas present from measurements within a cased well, and then quantitatively determining the separate amounts of oil and gas present in the formation. Resistivity measurements are obtained from within the cased well by conducting A.C. current from within the cased well to a remote electrode at a frequency that is within the frequency range of 0.1 Hz to 20 Hz.

Vail, III, William Banning (Bothell, WA)

2000-01-01T23:59:59.000Z

269

A preparative suspension culture system permitting quantitation of anchorage-independent growth by direct radiolabeling of cellular DNA  

SciTech Connect

We have developed a hybrid methylcellulose/agar suspension culture system which permits long-term colony formation of transformed mesenchymal cells. In contrast to traditional agar suspensions, our system allows for recovery of cells and direct biochemical analysis of anchorage-independent growth. The ability to readily radiolabel cellular macromolecules in these preparative cultures permits a quantitative and objective analysis of colony formation by incorporation of (/sup 3/H)thymidine into newly synthesized DNA.

Assoian, R.K.; Boardman, L.A.; Drosinos, S.

1989-02-15T23:59:59.000Z

270

Systems Approach and Quantitative Decision Tools for Technology Selection in Environmentally Friendly Drilling  

E-Print Network (OSTI)

One of the petroleum industry?s goals is to reduce the environmental impact of oil and gas operations in environmentally sensitive areas. To achieve this, a number of Environmentally Friendly Drilling (EFD) technologies have been developed to varying degrees. For example, the use of an elevated platform as an alternative to the gravel pad is less intrusive and leads to a more environmentally friendly approach to drilling operations. Elevated drilling platforms will require the use of piles. Another alternative to the gravel pad is the use of composite mats. Since the demand of low impact technologies for drill site construction has rapidly increased, the parametric study for the feasibility of using pile foundations and composite mats is conducted in this research. Even though a number of EFD technologies have already been developed to varying degrees, few have been integrated into a field demonstrable drilling system (i.e., combination of technologies) compatible with ecologically sensitive areas. In general, it is difficult to select the best combination of EFD technologies for a given site because there are many possible combinations and many different evaluation criteria. The proposed technology evaluation method is based on a systems analysis that can be used for integrating current and new EFD technologies into an optimal EFD system. An optimization scheme is suggested based on a combination of multi-attribute utility theory and exhaustively enumerating all possible technology combinations to provide a quantitative rationale and suggest the best set of systems according to a set of criteria, with the relative importance of the different criteria defined by the decision-maker. In this research, the sensitivity of the optimal solution to the weight factors and the effects of the uncertainty of input scores are also discussed using a case study. An application of the proposed approach is described by conducting a case study in Green Lake at McFaddin, TX. The main purpose of this case study is to test the proposed technology evaluation protocol in a real site and then to refine the protocol. This research describes the results of the case study which provided a more logical and comprehensive approach that maximized the economic and environmental goals of both the landowner and the oil company leaseholder.

Yu, Ok Y.

2009-05-01T23:59:59.000Z

271

Genital Herpes Evaluation by Quantitative TaqMan PCR: Correlating Single Detection and Quantity of HSV-2 DNA in Cervicovaginal Lavage Fluids with Cross-sectional and Longitudinal Clinical Data.  

E-Print Network (OSTI)

by quantitative TaqMan PCR: correlating single detection andof a quantitative competitive PCR assay for measuring herpessamples by a real-time taqman PCR assay. J Med Virol 2005,

2010-01-01T23:59:59.000Z

272

Genome anchored QTLs for biomass productivity in Hybrid Populus: Heterosis and detection across Contrasting Environments.  

Science Conference Proceedings (OSTI)

Traits related to biomass production were analyzed for the presence of quantitative trait loci (QTLs) in an interspecific F2 population derived from an outbred Populus trichocarpa P. deltoides parental cross. Three years of phenotypic data for stem growth traits (height and diameter) were collected from two parental, two F1 and 339 F2 trees in a clonal trial replicated both within and among two environmentally contrasting sites in the North American Pacific Northwest. A genetic linkage map comprised of 841 SSR, AFLP, and RAPD markers and phenotypic data from 310 progeny were used to identify genomic regions harboring QTL using the Multiple-QTL Model (MQM) package of the statistical program MapQTL 6. A total of twelve QTLs, nine putative and three suggestive, were identified with eight of these being identified at both sites in at least one experiment. Of these, three putative QTL BM-1, BM-2, BM-7, on LGs I, II, and XIV, respectively, were identified in all three years for both height and diameter. Two QTLs BM-2 and BM-7, on LG II and XIV, respectively, exhibited significant evidence of over-dominance in all three years for both traits. Conversely a QTL on BM-6 LG XIII exhibited out-breeding depression in two years for both height and diameter. The remaining nine QTLs showed difference levels of dominance and additive effects. Seven of the nine QTL were successfully anchored and QTL peak positions were estimated for each one on the P. trichocarpa genome assembly using flanking SSR markers with known physical positions positions. QTL BM-7 on LG XIV had been anchored on the genome assembly in a previous study, therefore eight QTLs identified in this study were assigned genome assembly positions. Physical distances encompassed by each QTL regions ranged from 1.3 to 8.8 Mb.

Muchero, Wellington [ORNL; Sewell, Mitchell [ORNL; Gunter, Lee E [ORNL; Tschaplinski, Timothy J [ORNL; Yin, Tongming [ORNL; DiFazio, Steven P [West Virginia University; Tuskan, Gerald A [ORNL

2013-01-01T23:59:59.000Z

273

Modern Methods for Lipid AnalysisChapter 7 Qualitative and Quantitative Analysis of Triacylglycerolsby Atmospheric Pressure Ionization (APCI and ESI) Mass Spectrometry Techniques  

Science Conference Proceedings (OSTI)

Modern Methods for Lipid Analysis Chapter 7 Qualitative and Quantitative Analysis of Triacylglycerolsby Atmospheric Pressure Ionization (APCI and ESI) Mass Spectrometry Techniques Methods and Analyses eChapters Methods - Analyses Books AO

274

MASIC: a software program for fast quantitation and flexible visualization of chromatographic profiles from detected LC-MS(/MS) features  

SciTech Connect

Quantitative analysis of liquid chromatography (LC)- mass spectrometry (MS) and tandem mass spectrometry (MS/MS) data is essential to many proteomics studies. We have developed MASIC to accurately measure peptide abundances and LC elution times in low-resolution LC-MS/MS analyses. This software program uses an efficient processing algorithm to quickly generate mass specific selected ion chromatograms from a dataset and provides an interactive browser that allows users to examine individual chromatograms in a variety of fashions. The improved elution time estimates afforded by MASIC increase the utility of LC-MS/MS data in the accurate mass and time (AMT) tag approach to proteomics.

Monroe, Matthew E.; Shaw, Jason L.; Daly, Don S.; Adkins, Joshua N.; Smith, Richard D.

2008-06-01T23:59:59.000Z

275

Soil loss and leaching, habitat destruction, land and water demand in energy-crop monoculture: some quantitative limits  

DOE Green Energy (OSTI)

The environmental impacts of growing biomass for energy, especially for liquid automotive fuels, are potentially large. They are sensitive to the low power production per unit area (high land requirement) and to net energy balances. Initial quantitative estimates were made for impacts per unit power within several classes of impacts, and conversely, for limits to power produced if one avoids worst-class impacts. The following types of biomass energy technologies are considered: ethanol and methanol from grains and residues (temperate zone); jojoba wax (semi-tropical); ethanol from sugar cane and root crops (tropics); and silviculture for methanol via gasification.

Gutschick, V.P.

1981-01-01T23:59:59.000Z

276

Star-Like Micelles with Star-Like Interactions: A quantitative Evaluation of Structure Factor and Phase Diagram  

E-Print Network (OSTI)

PEP-PEO block copolymer micelles offer the possibility to investigate phase behaviour and interactions of star polymers (ultra-soft colloids). A star-like architecture is achieved by an extremely asymmetric block ratio (1:20). Micellar functionality f can be smoothly varied by changing solvent composition (interfacial tension). Structure factors obtained by SANS can be quantitatively described in terms of an effective potential developed for star polymers. The experimental phase diagram reproduces to a high level of accuracy the predicted liquid/solid transition. Whereas for intermediate f a bcc phase is observed, for high f the formation of a fcc phase is preempted by glass formation.

M. Laurati; J. Stellbrink; R. Lund; L. Willner; D. Richter; E. Zaccarelli

2005-05-04T23:59:59.000Z

277

Quantitative Vapor-phase IR Intensities and DFT Computations to Predict Absolute IR Spectra based on Molecular Structure: I. Alkanes  

SciTech Connect

Recently recorded quantitative IR spectra of a variety of gas-phase alkanes are shown to have integrated intensities in both the C-H stretching and C-H bending regions that depend linearly on the molecular size, i.e. the number of C-H bonds. This result is well predicted from CH4 to C15H32 by DFT computations of IR spectra at the B3LYP/6-31+G(d,p) level of DFT theory. A simple model predicting the absolute IR band intensities of alkanes based only on structural formula is proposed: For the C-H stretching band near 2930 cm-1 this is given by (in km/mol): CH¬_str = (34±3)*CH – (41±60) where CH is number of C-H bonds in the alkane. The linearity is explained in terms of coordinated motion of methylene groups rather than the summed intensities of autonomous -CH2- units. The effect of alkyl chain length on the intensity of a C-H bending mode is explored and interpreted in terms of conformer distribution. The relative intensity contribution of a methyl mode compared to the total C-H stretch intensity is shown to be linear in the number of terminal methyl groups in the alkane, and can be used to predict quantitative spectra a priori based on structure alone.

Williams, Stephen D.; Johnson, Timothy J.; Sharpe, Steven W.; Yavelak, Veronica; Oats, R. P.; Brauer, Carolyn S.

2013-11-13T23:59:59.000Z

278

Quantitative planar laser-induced fluorescence imaging of multi-component fuel/air mixing in a firing gasoline-direct-injection engine: Effects of residual exhaust gas on quantitative PLIF  

SciTech Connect

A study of in-cylinder fuel-air mixing distributions in a firing gasoline-direct-injection engine is reported using planar laser-induced fluorescence (PLIF) imaging. A multi-component fuel synthesised from three pairs of components chosen to simulate light, medium and heavy fractions was seeded with one of three tracers, each chosen to co-evaporate with and thus follow one of the fractions, in order to account for differential volatility of such components in typical gasoline fuels. In order to make quantitative measurements of fuel-air ratio from PLIF images, initial calibration was by recording PLIF images of homogeneous fuel-air mixtures under similar conditions of in-cylinder temperature and pressure using a re-circulation loop and a motored engine. This calibration method was found to be affected by two significant factors. Firstly, calibration was affected by variation of signal collection efficiency arising from build-up of absorbing deposits on the windows during firing cycles, which are not present under motored conditions. Secondly, the effects of residual exhaust gas present in the firing engine were not accounted for using a calibration loop with a motored engine. In order to account for these factors a novel method of PLIF calibration is presented whereby 'bookend' calibration measurements for each tracer separately are performed under firing conditions, utilising injection into a large upstream heated plenum to promote the formation of homogeneous in-cylinder mixtures. These calibration datasets contain sufficient information to not only characterise the quantum efficiency of each tracer during a typical engine cycle, but also monitor imaging efficiency, and, importantly, account for the impact of exhaust gas residuals (EGR). By use of this method EGR is identified as a significant factor in quantitative PLIF for fuel mixing diagnostics in firing engines. The effects of cyclic variation in fuel concentration on burn rate are analysed for different fuel injection strategies. Finally, mixture distributions for late injection obtained using quantitative PLIF are compared to predictions of computational fluid dynamics calculations. (author)

Williams, Ben; Ewart, Paul [Department of Physics, Oxford University, Parks Road, Oxford OX1 3PU (United Kingdom); Wang, Xiaowei; Stone, Richard [Department of Engineering Science, Oxford University, Parks Road, Oxford OX1 3PJ (United Kingdom); Ma, Hongrui; Walmsley, Harold; Cracknell, Roger [Shell Global Solutions (UK), Shell Research Centre Thornton, P. O. Box 1, Chester, CH1 3SH (United Kingdom); Stevens, Robert; Richardson, David; Fu, Huiyu; Wallace, Stan [Jaguar Cars, Engineering Centre, Abbey Road, Whitley, Coventry, CV3 4LF (United Kingdom)

2010-10-15T23:59:59.000Z

279

A 34K SNP genotyping array for Populus trichocarpa: design, application to the study of natural populations and transferability to other Populus species  

SciTech Connect

Genetic mapping of quantitative traits requires genotypic data for large numbers of markers in many individuals. Despite the declining costs of genotyping by sequencing, for most studies, the use of large SNP genotyping arrays still offers the most cost-effective solution for large-scale targeted genotyping. Here we report on the design and performance of a SNP genotyping array for Populus trichocarpa (black cottonwood). This genotyping array was designed with SNPs pre-ascertained in 34 wild accessions covering most of the species range. Due to the rapid decay of linkage disequilibrium in P. trichocarpa we adopted a candidate gene approach to the array design that resulted in the selection of 34,131 SNPs, the majority of which are located in, or within 2 kb, of 3,543 candidate genes. A subset of the SNPs (539) was selected based on patterns of variation among the SNP discovery accessions. We show that more than 95% of the loci produce high quality genotypes and that the genotyping error rate for these is likely below 2%, indicating that high-quality data are generated with this array. We demonstrate that even among small numbers of samples (n=10) from local populations over 84% of loci are polymorphic. We also tested the applicability of the array to other species in the genus and found that due to ascertainment bias the number of polymorphic loci decreases rapidly with genetic distance, with the largest numbers detected in other species in section Tacamahaca (P. balsamifera and P. angustifolia). Finally, we provide evidence for the utility of the array for intraspecific studies of genetic differentiation and for species assignment and the detection of natural hybrids.

Geraldes, Armando [University of British Columbia, Vancouver; Hannemann, Jan [University of Victoria, Canada; Grassa, Chris [University of British Columbia, Vancouver; Farzaneh, Nima [University of British Columbia, Vancouver; Porth, Ilga [University of British Columbia, Vancouver; McKown, Athena [University of British Columbia, Vancouver; Skyba, Oleksandr [University of British Columbia, Vancouver; Li, Eryang [University of British Columbia, Vancouver; Mike, Fujita [University of British Columbia, Vancouver; Friedmann, Michael [University of British Columbia, Vancouver; Wasteneys, Geoffrey [University of British Columbia, Vancouver; Guy, Robert [University of British Columbia, Vancouver; El-Kassaby, Yousry [University of British Columbia, Vancouver; Mansfield, Shawn [University of British Columbia, Vancouver; Cronk, Quentin [University of British Columbia, Vancouver; Ehlting, Juergen [University of Victoria, Canada; Douglas, Carl [University of British Columbia, Vancouver; DiFazio, Stephen P [West Virginia University, Morgantown; Slavov, Gancho [West Virginia University, Morgantown; Ranjan, Priya [ORNL; Muchero, Wellington [ORNL; Gunter, Lee E [ORNL; Wymore, Ann [ORNL; Tuskan, Gerald A [ORNL; Martin, Joel [U.S. Department of Energy, Joint Genome Institute; Schackwitz, Wendy [U.S. Department of Energy, Joint Genome Institute; Pennacchio, Christa [U.S. Department of Energy, Joint Genome Institute; Rokhsar, Daniel [U.S. Department of Energy, Joint Genome Institute

2013-01-01T23:59:59.000Z

280

Quantitative size-dependent structure and strain determination of CdSe nanoparticles using atomic pair distribution function analysis  

E-Print Network (OSTI)

The size-dependent structure of CdSe nanoparticles, with diameters ranging from 2 to 4 nm, has been studied using the atomic pair distribution function (PDF) method. The core structure of the measured CdSe nanoparticles can be described in terms of the wurtzite atomic structure with extensive stacking faults. The density of faults in the nanoparticles ~50% . The diameter of the core region was extracted directly from the PDF data and is in good agreement with the diameter obtained from standard characterization methods suggesting that there is little surface amorphous region. A compressive strain was measured in the Cd-Se bond length that increases with decreasing particle size being 0.5% with respect to bulk CdSe for the 2 nm diameter particles. This study demonstrates the size-dependent quantitative structural information that can be obtained even from very small nanoparticles using the PDF approach.

A. S. Masadeh; E. Bozin; C. L. Farrow; G. Paglia; P. Juhas; A. Karkamkar; M. G. Kanatzidis; S. J. L. Billinge

2007-04-10T23:59:59.000Z

Note: This page contains sample records for the topic "quantitative trait loci" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


281

UPDATE February 2012 - The Food Crises: Predictive validation of a quantitative model of food prices including speculators and ethanol conversion  

E-Print Network (OSTI)

Increases in global food prices have led to widespread hunger and social unrest---and an imperative to understand their causes. In a previous paper published in September 2011, we constructed for the first time a dynamic model that quantitatively agreed with food prices. Specifically, the model fit the FAO Food Price Index time series from January 2004 to March 2011, inclusive. The results showed that the dominant causes of price increases during this period were investor speculation and ethanol conversion. The model included investor trend following as well as shifting between commodities, equities and bonds to take advantage of increased expected returns. Here, we extend the food prices model to January 2012, without modifying the model but simply continuing its dynamics. The agreement is still precise, validating both the descriptive and predictive abilities of the analysis. Policy actions are needed to avoid a third speculative bubble that would cause prices to rise above recent peaks by the end of 2012.

Lagi, Marco; Bertrand, Karla Z; Bar-Yam, Yaneer

2012-01-01T23:59:59.000Z

282

Quantitative comparison between the degree of domain orientation and nonlinear properties of a PZT ceramic during electrical and mechanical loading  

Science Conference Proceedings (OSTI)

The macroscopic electromechanical coupling properties of ferroelectric polycrystals are composed of linear and nonlinear contributions. The nonlinear contribution is typically associated with the extrinsic effects related to the creation and motion of domain walls. To quantitatively compare the macroscopic nonlinear properties of a lead zirconate titanate ceramic and the degree of domain orientation, in-situ neutron and high-energy x-ray diffraction experiments are performed and they provide the domain orientation density as a function of the external electric field and mechanical compression. Furthermore, the macroscopic strain under the application of external electrical and mechanical loads is measured and the nonlinear strain is calculated by means of the linear intrinsic piezoelectric effect and the linear intrinsic elasticity. The domain orientation density and the nonlinear strain show the same dependence on the external load. The scaling factor that relates to the two values is constant and is the same for both electrical and mechanical loadings.

Marsilius, Mie; Granzow, Torsten; Jones, Jacob L. (Florida); (Darmstadt)

2011-10-26T23:59:59.000Z

283

Pursuing genius loci: interaction design and natural places  

Science Conference Proceedings (OSTI)

Human computer interaction (HCI) has little explored everyday life and enriching experiences in rural, wilderness and other predominantly "natural" places despite their socioeconomic importance. Beyond simply addressing the challenge arising from applying ... Keywords: Dialogic, Embodiment, Feltlife, Habitus, Indexicality, Natural places, Nature, Rural, Spatial practices, Wilderness

Nicola J. Bidwell; David Browning

2010-01-01T23:59:59.000Z

284

TECHNICAL NOTE Identification and characterization of nuclear microsatellite loci  

E-Print Network (OSTI)

= 1], Cameron:TX [n = 1]), P. fouquettei (Beauregard:LA [n = 1], Lamar:TX [n = 1]), P. kalmi (Accomack

Ronquist, Fredrik

285

The institutional environment for B2B e-commerce adoption: a quantitative study of electronics and textiles firms in Greater China and the USA  

Science Conference Proceedings (OSTI)

Grounding on the institutional theory and IT adoption literature, we conduct a quantitative analysis assessing the effects of industrial, governmental, regulatory and cultural factors on the initial stages of B2B e-commerce adoption. Our analysis ... Keywords: B2B, China, Hong Kong, Taiwan, USA, e-commerce, electronics, institutional environment, textiles

Ling Zhu; Sherry M. B. Thatcher

2007-01-01T23:59:59.000Z

286

Evaluation and Uncertainty Estimation of NOAA/NSSL Next-Generation National Mosaic Quantitative Precipitation Estimation Product (Q2) over the Continental United States  

Science Conference Proceedings (OSTI)

Quantitative precipitation estimation (QPE) products from the next-generation National Mosaic and QPE system (Q2) are cross-compared to the operational, radar-only product of the National Weather Service (Stage II) using the gauge-adjusted and ...

Sheng Chen; Jonathan J. Gourley; Yang Hong; P. E. Kirstetter; Jian Zhang; Kenneth Howard; Zachary L. Flamig; Junjun Hu; Youcun Qi

2013-08-01T23:59:59.000Z

287

Quantitative 3-D Elemental Mapping by LA-ICP-MS of a Basaltic Clast from the Hanford 300 Area, Washington, USA  

E-Print Network (OSTI)

Quantitative 3-D Elemental Mapping by LA-ICP-MS of a Basaltic Clast from the Hanford 300 Area collected from the Hanford 300 Area in south-central Washington State, United States. A calibration method and riparian quality in many locations, most notably at the Hanford, Savannah River, Oak Ridge, and Nevada Test

Hu, Qinhong "Max"

288

Development of catechol 2,3-dioxygenase-specific primers for monitoring bioremediation by competitive quantitative PCR  

Science Conference Proceedings (OSTI)

Benzene, toluene, xylenes, phenol, naphthalene, and biphenyl are among a group of compounds that have at least one reported pathway for biodegradation involving catechol 2,3-dioxygenase enzymes. Thus, detection of the corresponding catechol 2,3-dioxygenase genes can serve as a basis for identifying and quantifying bacteria that have these catabolic abilities. Primes that can successfully amplify a 238-bp catechol 2,3-dioxygenase gene fragment from eight different bacteria are described. The identities of the amplicons were confirmed by hybridization with a 238-bp catechol 2,3-dioxygenase probe. The detection limit was 10{sup 2} to 10{sup 3} gene copies, which was lowered to 10{sup 0} to 10{sup 1} gene copies of hybridization. Using the dioxygenase-specific primers, an increase in catechol 2,3-dioxygenase genes was detected in petroleum-amended soils. The dioxygenase genes were enumerated by competitive quantitative PCR and a 163-bp competitor that was amplified using the same primers. Target and competitor sequences had identical amplification kinetics. Potential PCR inhibitors that could coextract with DNA, nonamplifying DNA, soil factors (humics), and soil pollutants (toluene) did not impact enumeration. Therefore, this technique can be used to accurately and reproducibly quantify catechol 2,3-dioxygenase genes in complex environments such as petroleum-contaminated soil. Direct, non-cultivation-based molecular techniques for detecting and enumerating microbial pollutant-biodegrading genes in environmental samples are powerful tools for monitoring bioremediation and developing field evidence in support of natural attenuation.

Mesarch, M.B.; Nakatsu, C.H.; Nies, L.

2000-02-01T23:59:59.000Z

289

THE EVOLUTION OF SOLAR FLUX FROM 0.1 nm TO 160 {mu}m: QUANTITATIVE ESTIMATES FOR PLANETARY STUDIES  

Science Conference Proceedings (OSTI)

Understanding changes in the solar flux over geologic time is vital for understanding the evolution of planetary atmospheres because it affects atmospheric escape and chemistry, as well as climate. We describe a numerical parameterization for wavelength-dependent changes to the non-attenuated solar flux appropriate for most times and places in the solar system. We combine data from the Sun and solar analogs to estimate enhanced UV and X-ray fluxes for the young Sun and use standard solar models to estimate changing visible and infrared fluxes. The parameterization, a series of multipliers relative to the modern top of the atmosphere flux at Earth, is valid from 0.1 nm through the infrared, and from 0.6 Gyr through 6.7 Gyr, and is extended from the solar zero-age main sequence to 8.0 Gyr subject to additional uncertainties. The parameterization is applied to a representative modern day flux, providing quantitative estimates of the wavelength dependence of solar flux for paleodates relevant to the evolution of atmospheres in the solar system (or around other G-type stars). We validate the code by Monte Carlo analysis of uncertainties in stellar age and flux, and with comparisons to the solar proxies {kappa}{sup 1} Cet and EK Dra. The model is applied to the computation of photolysis rates on the Archean Earth.

Claire, Mark W. [School of Environmental Sciences, University of East Anglia, Norwich, UK NR4 7TJ (United Kingdom); Sheets, John; Meadows, Victoria S. [Virtual Planetary Laboratory and Department of Astronomy, University of Washington, Box 351580, Seattle, WA 98195 (United States); Cohen, Martin [Radio Astronomy Laboratory, University of California, Berkeley, CA 94720-3411 (United States); Ribas, Ignasi [Institut de Ciencies de l'Espai (CSIC-IEEC), Facultat de Ciencies, Torre C5 parell, 2a pl, Campus UAB, E-08193 Bellaterra (Spain); Catling, David C., E-mail: M.Claire@uea.ac.uk [Virtual Planetary Laboratory and Department of Earth and Space Sciences, University of Washington, Box 351310, Seattle, WA 98195 (United States)

2012-09-20T23:59:59.000Z

290

Quantitative analysis of the effects of strain-state on the microstructure and J{sub c} of BSCCO tapes  

Science Conference Proceedings (OSTI)

After considerable optimization efforts, conventional thermomechanical processing of long, high temperature superconductors has not produced critical current densities (J{sub c}) adequate for most liquid nitrogen temperature applications. New approaches are needed to improve the J{sub c} of superconducting tape produced by co-deforming a ductile silver sheath containing the superconducting oxide using the powder-in-tube process. This study investigates improvements in J{sub c} generated by modifying the strain-state during rolling of silver-sheathed Bi{sub 2}Sr{sub 2}Ca{sub 2}Cu{sub 3}O{sub 10+x} (BSCCO-2223) tape using quantitative image analysis of the different phases. Pure compression and combined compression-shear loading was achieved by embedding BSCCO-2223 tapes at different locations within thick steel blocks. High hydrostatic compressive stress was imposed by confining the tape width. Tapes deformed with combined shear-compression exhibited measurably higher J{sub c} values than tapes subjected to pure compression, but their microstructures showed little difference in the amount of nonconducting (including porosity) phase content. However, constraining the tape width resulted in the most significant increase in J{sub c} which corresponded to a much lower porosity and nonconducting phase volume in the oxide near the tape edge.

Blumenthal, W.R.; Zhu, Y.T.; Sebring, R.J.; Lowe, T.C. [Los Alamos National Lab., NM (United States). Materials Science and Technology Div.; Asaro, R.J. [Univ. of California, San Diego, La Jolla, CA (United States). Dept. of Applied Mechanics and Engineering Sciences

1996-04-01T23:59:59.000Z

291

Quantitative Changes in Hydrocarbons over Time in Fecal Pellets of Incisitermes minor May Predict Whether Colonies Are Alive or Dead  

E-Print Network (OSTI)

# The Author(s) 2010. This article is published with open access at Springerlink.com Abstract Hydrocarbon mixtures extracted from fecal pellets of drywood termites are species-specific and can be characterized to identify the termites responsible for damage, even when termites are no longer present or are unable to be recovered easily. In structures infested by drywood termites, it is common to find fecal pellets, but difficult to sample termites from the wood. When fecal pellets appear after remedial treatment of a structure, it is difficult to determine whether this indicates that termites in the structure are still alive and active or not. We examined the hydrocarbon composition of workers, alates, and soldiers of Incisitermes minor (Hagen) (family Kalotermitidae) and of fecal pellets of workers. Hydrocarbons were qualitatively similar among castes and pellets. Fecal pellets that were aged for periods of 0, 30, 90, and 365 days after collection were qualitatively similar across all time periods, however, the relative quantities of certain individual hydrocarbons changed over time, with 19 of the 73 hydrocarbon peaks relatively increasing or decreasing. When the sums of the positive and negative slopes of these 19 hydrocarbons were indexed, they produced a highly significant linear correlation (R 2 =0.89). Consequently, the quantitative differences of these hydrocarbons peaks can be used to determine the age of worker fecal pellets, and thus help determine whether the colony that produced them is alive or dead.

Vernard R. Lewis; Lori J. Nelson; Michael I. Haverty; James A. Baldwin

2010-01-01T23:59:59.000Z

292

D-Factor: A Quantitative Model of Application Slow-Down in Multi-Resource Shared Systems  

SciTech Connect

Scheduling multiple jobs onto a platform enhances system utilization by sharing resources. The benefits from higher resource utilization include reduced cost to construct, operate, and maintain a system, which often include energy consumption. Maximizing these benefits comes at a price - resource contention among jobs increases job completion time. In this paper, we analyze slow-downs of jobs due to contention for multiple resources in a system; referred to as dilation factor. We observe that multiple-resource contention creates non-linear dilation factors of jobs. From this observation, we establish a general quantitative model for dilation factors of jobs in multi-resource systems. A job is characterized by a vector-valued loading statistics and dilation factors of a job set are given by a quadratic function of their loading vectors. We demonstrate how to systematically characterize a job, maintain the data structure to calculate the dilation factor (loading matrix), and calculate the dilation factor of each job. We validate the accuracy of the model with multiple processes running on a native Linux server, virtualized servers, and with multiple MapReduce workloads co-scheduled in a cluster. Evaluation with measured data shows that the D-factor model has an error margin of less than 16%. We also show that the model can be integrated with an existing on-line scheduler to minimize the makespan of workloads.

Lim, Seung-Hwan [ORNL; Huh, Jae-Seok [ORNL; Kim, Youngjae [ORNL; Shipman, Galen M [ORNL; Das, Chita [Pennsylvania State University, University Park, PA

2012-01-01T23:59:59.000Z

293

Quantitative Proteomic Analysis of Mouse Embryonic Fibroblasts and Induced Pluripotent Stem Cells Using 16O /18O labeling  

Science Conference Proceedings (OSTI)

Induced pluripotent stem cells (iPSC) hold great promise for regenerative medicine as well as for investigations into the pathogenesis and treatment of various diseases. Understanding of key intracellular signaling pathways and protein targets that control development of iPSC from somatic cells is essential for designing new approaches to improve reprogramming efficiency. Here we report the development and application of an integrated quantitative proteomics platform for investigating differences in protein expressions between mouse embryonic fibroblasts (MEF) and MEF-derived iPSC. This platform consists of 16O/18O labeling, multidimensional peptide separation coupled with tandem mass spectrometry, and data analysis with UNiquant software. Using this platform a total of 2,481 proteins were identified and quantified from the 16O/18O-labeled MEF-iPSC proteome mixtures with a false discovery rate of 0.01. Among them, 218 proteins were significantly upregulated, while 247 proteins were significantly downregulated in iPSC compared to MEF. Many nuclear proteins, including Hdac1, Dnmt1, Pcna, Ccnd1, Smarcc1, and subunits in DNA replication and RNA polymerase II complex were found to be enhanced in iPSC. Protein network analysis revealed that Pcna functions as a hub orchestrating complicated mechanisms including DNA replication, epigenetic inheritance (Dnmt1) and chromatin remodeling (Smarcc1) to reprogram MEF and maintain stemness of iPSC.

Huang, Xin; Tian, Changhai; Liu, Miao; Wang, Yongxiang; Tolmachev, Aleksey V.; Sharma, Seema; Yu, Fang; Fu, Kai; Zheng, Jialin; Ding, Shi-Jian

2012-04-06T23:59:59.000Z

294

Quantitative analysis of privatization  

E-Print Network (OSTI)

In recent years, the economic policy of privatization, which is defined as the transfer of property or responsibility from public sector to private sector, is one of the global phenomenon that increases use of markets to allocate resources. One important motivation for privatization is to help develop factor and product markets, as well as security markets. Progress in privatization is correlated with improvements in perceived political and investment risk. Many emerging countries have gradually reduced their political risks during the course of sustained privatization. In fact, most risk resolution seems to take place as privatization proceeds to its later stage. Alternative benefits of privatization are improved risk sharing and increased liquidity and activity of the market. One of the main methods to develop privatization is entering a new stock to the markets for arising competition. However, attention to the capability of the markets to accept a new stock is substantial. Without considering the above st...

Vahabi, M

2008-01-01T23:59:59.000Z

295

Quantitative DNA fiber mapping  

DOE Patents (OSTI)

The present invention relates generally to the DNA mapping and sequencing technologies. In particular, the present invention provides enhanced methods and compositions for the physical mapping and positional cloning of genomic DNA. The present invention also provides a useful analytical technique to directly map cloned DNA sequences onto individual stretched DNA molecules.

Gray, Joe W. (San Francisco, CA); Weier, Heinz-Ulrich G. (Oakland, CA)

1998-01-01T23:59:59.000Z

296

Quantitative luminescence imaging system  

DOE Patents (OSTI)

The QLIS images and quantifies low-level chemiluminescent reactions in an electromagnetic field. It is capable of real time nonperturbing measurement and simultaneous recording of many biochemical and chemical reactions such as luminescent immunoassays or enzyme assays. The system comprises image transfer optics, a low-light level digitizing camera with image intensifying microchannel plates, an image process or, and a control computer. The image transfer optics may be a fiber image guide with a bend, or a microscope, to take the light outside of the RF field. Output of the camera is transformed into a localized rate of cumulative digitalized data or enhanced video display or hard-copy images. The system may be used as a luminescent microdosimetry device for radiofrequency or microwave radiation, as a thermal dosimeter, or in the dosimetry of ultra-sound (sonoluminescence) or ionizing radiation. It provides a near-real-time system capable of measuring the extremely low light levels from luminescent reactions in electromagnetic fields in the areas of chemiluminescence assays and thermal microdosimetry, and is capable of near-real-time imaging of the sample to allow spatial distribution analysis of the reaction. It can be used to instrument three distinctly different irradiation configurations, comprising (1) RF waveguide irradiation of a small Petri-dish-shaped sample cell, (2) RF irradiation of samples in a microscope for the microscopic imaging and measurement, and (3) RF irradiation of small to human body-sized samples in an anechoic chamber. 22 figs.

Erwin, D.N.; Kiel, J.L.; Batishko, C.R.; Stahl, K.A.

1990-08-14T23:59:59.000Z

297

Quantitative luminescence imaging system  

DOE Patents (OSTI)

The QLIS images and quantifies low-level chemiluminescent reactions in an electromagnetic field. It is capable of real time nonperturbing measurement and simultaneous recording of many biochemical and chemical reactions such as luminescent immunoassays or enzyme assays. The system comprises image transfer optics, a low-light level digitizing camera with image intensifying microchannel plates, an image process or, and a control computer. The image transfer optics may be a fiber image guide with a bend, or a microscope, to take the light outside of the RF field. Output of the camera is transformed into a localized rate of cumulative digitalized data or enhanced video display or hard-copy images. The system may be used as a luminescent microdosimetry device for radiofrequency or microwave radiation, as a thermal dosimeter, or in the dosimetry of ultra-sound (sonoluminescence) or ionizing radiation. It provides a near-real-time system capable of measuring the extremely low light levels from luminescent reactions in electromagnetic fields in the areas of chemiluminescence assays and thermal microdosimetry, and is capable of near-real-time imaging of the sample to allow spatial distribution analysis of the reaction. It can be used to instrument three distinctly different irradiation configurations, comprising (1) RF waveguide irradiation of a small Petri-dish-shaped sample cell, (2) RF irradiation of samples in a microscope for the microscopie imaging and measurement, and (3) RF irradiation of small to human body-sized samples in an anechoic chamber.

Erwin, David N. (San Antonio, TX); Kiel, Johnathan L. (San Antonio, TX); Batishko, Charles R. (West Richland, WA); Stahl, Kurt A. (Richland, WA)

1990-01-01T23:59:59.000Z

298

Quantitative Infrared Database  

Science Conference Proceedings (OSTI)

... Benzene, 2.1 %, Boxcar, 2 1 0.5 0.25 0.125. Triangular, 2 1 0.5 0.25 0.125. ... Ethyl benzene, 2.1 %, Boxcar, 2 1 0.5 0.25 0.125. ...

2013-07-15T23:59:59.000Z

299

Quantitative Infrared Database  

Science Conference Proceedings (OSTI)

... Table II: Compound#, Compound Name, 001, Benzene, 002, Ethylene, 003, Acetone, 004, Ethanol, 005, Methanol, 006, 2-propanol, 007, Ethyl Acetatev ...

300

Quantitative Analysis of Tetramethylenedisulfotetramine ("Tetramine") Spiked into Beverages by Liquid Chromatography Tandem Mass Spectrometry with Validation by Gas Chromatography Mass Spectrometry  

Science Conference Proceedings (OSTI)

Tetramethylenedisulfotetramine, commonly known as tetramine, is a highly neurotoxic rodenticide (human oral LD{sub 50} = 0.1 mg/kg) used in hundreds of deliberate food poisoning events in China. Here we describe a method for quantitation of tetramine spiked into beverages, including milk, juice, tea, cola, and water and cleaned up by C8 solid phase extraction and liquid-liquid extraction. Quantitation by high performance liquid chromatography tandem mass spectrometry (LC/MS/MS) was based upon fragmentation of m/z 347 to m/z 268. The method was validated by gas chromatography mass spectrometry (GC/MS) operated in SIM mode for ions m/z 212, 240, and 360. The limit of quantitation was 0.10 {micro}g/mL by LC/MS/MS versus 0.15 {micro}g/mL for GC/MS. Fortifications of the beverages at 2.5 {micro}g/mL and 0.25 {micro}g/mL were recovered ranging from 73-128% by liquid-liquid extraction for GC/MS analysis, 13-96% by SPE and 10-101% by liquid-liquid extraction for LC/MS/MS analysis.

Owens, J; Hok, S; Alcaraz, A; Koester, C

2008-11-13T23:59:59.000Z

Note: This page contains sample records for the topic "quantitative trait loci" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


301

Development of a computer-aided fault tree synthesis methodology for quantitative risk analysis in the chemical process industry  

E-Print Network (OSTI)

There has been growing public concern regarding the threat to people and environment from industrial activities, thus more rigorous regulations. The investigation of almost all the major accidents shows that we could have avoided those tragedies with effective risk analysis and safety management programs. High-quality risk analysis is absolutely necessary for sustainable development. As a powerful and systematic tool, fault tree analysis (FTA) has been adapted to the particular need of chemical process quantitative risk analysis (CPQRA) and found great applications. However, the application of FTA in the chemical process industry (CPI) is limited. One major barrier is the manual synthesis of fault trees. It requires a thorough understanding of the process and is vulnerable to individual subjectivity. The quality of FTA can be highly subjective and variable. The availability of a computer-based FTA methodology will greatly benefit the CPI. The primary objective of this research is to develop a computer-aided fault tree synthesis methodology for CPQRA. The central idea is to capture the cause-and-effect logic around each item of equipment directly into mini fault trees. Special fault tree models have been developed to manage special features. Fault trees created by this method are expected to be concise. A prototype computer program is provided to illustrate the methodology. Ideally, FTA can be standardized through a computer package that reads information contained in process block diagrams and provides automatic aids to assist engineers in generating and analyzing fault trees. Another important issue with regard to QRA is the large uncertainty associated with available failure rate data. In the CPI, the ranges of failure rates observed could be quite wide. Traditional reliability studies using point values of failure rates may result in misleading conclusions. This dissertation discusses the uncertainty with failure rate data and proposes a procedure to deal with data uncertainty in determining safety integrity level (SIL) for a safety instrumented system (SIS). Efforts must be carried out to obtain more accurate values of those data that might actually impact the estimation of SIL. This procedure guides process hazard analysts toward a more accurate SIL estimation and avoids misleading results due to data uncertainty.

Wang, Yanjun

2004-12-01T23:59:59.000Z

302

Textures in Strip-Cast Aluminum Alloys: Their On-Line Monitoring and Quantitative Effects on Formability. Final Technical Report  

Science Conference Proceedings (OSTI)

Aluminum sheets produced by continuous casting (CC) provide energy and economic savings of at least 25 and 14 percent, respectively, over sheets made from conventional direct chill (DC) ingot casting and rolling. As a result of the much simpler production route in continuous casting, however, the formability of CC aluminum alloys is often somewhat inferior to that of their DC counterparts. The mechanical properties of CC alloys can be improved by controlling their microstructure through optimal thermomechanical processing. Suitable annealing is an important means to improve the formability of CC aluminum alloy sheets. Recrystallization of deformed grains occurs during annealing, and it changes the crystallographic texture of the aluminum sheet. Laboratory tests in this project showed that this texture change can be detected by either laser-ultrasound resonance spectroscopy or resonance EMAT (electromagnetic acoustic transducer) spectroscopy, and that monitoring this change allows the degree of recrystallization or the ''recrystallized fraction'' in an annealed sheet to be ascertained. Through a plant trial conducted in May 2002, this project further demonstrated that it is feasible to monitor the recrystallized state of a continuous-cast aluminum sheet in-situ on the production line by using a laser-ultrasound sensor. When used in conjunction with inline annealing, inline monitoring of the recrystallized fraction by laser-ultrasound resonance spectroscopy offers the possibility of feed-back control that helps optimize processing parameters (e.g., annealing temperature), detect production anomalies, ensure product quality, and further reduce production costs of continuous-cast aluminum alloys. Crystallographic texture strongly affects the mechanical anisotropy/formability of metallic sheets. Clarification of the quantitative relationship between texture and anisotropy/formability of an aluminum alloy will render monitoring and control of its texture during the sheet production process even more meaningful. The present project included a study to determine how the anisotropic plastic behavior of a continuous-cast AA 5754 aluminum alloy depends on quantifiable texture coefficients. Formulae which show explicitly the effects of texture on the directional dependence of the q-value (a formability parameter) and of the uniaxial flow stress, respectively, were derived. Measurements made on a batch of as-received AA 5754 hot band and its O-temper counterpart corroborate the validity of these formulae. On the other hand, these measurements also indicate that some microstructure(s) other than texture could play a significant role in the plastic anisotropy of the AA 5754 alloy. For the q-value of a set of O-temper samples of this alloy, the additional microstructure that affects plastic anisotropy was shown to be grain shape. A formula that captures both the effects of crystallographic texture and grain shape on the q-value of the O-temper material was derived. A simple quadratic plastic potential that delivers this q-value formula was written down. Verification of the adequacy of this plastic potential, however, requires further investigations.

Man, Chi-Sing

2003-07-27T23:59:59.000Z

303

Development of a Standard Methodology for the Quantitative Measurement of Steel Phase Transformation Kinetics and Dilation Strains Using Dilatometric Methods, QMST (TRP 0015)  

Science Conference Proceedings (OSTI)

The purpose of this collaborative project was to develop a standard practice for obtaining and archiving quantitative steel transformation kinetic data and thermal strain data. Two families of dilatometric equipment were employed to develop this standard practice for testing bar product steels. These include high-speed quenching and deformation dilatometers and Gleeble{reg_sign} thermomechanical simulation instruments. Standard measurement, data interpretation and data reporting methods were developed and defined by the cross-industry QMST Consortium members consisting of steel-manufacturers, forgers, heat-treaters, modelers, automotive and heavy vehicle OEMs along with team expert technologists from the National Labs and academia. The team designed phase transformation experiments on two selected steel grades to validate the standard practices--a medium carbon grade SAE 1050 and an alloy steel SAE 8620. A final standard practice document was developed based on the two dilatometry methods, and was submitted to and approved by ASTM (available as A1033-04). The standard practice specifies a method for measuring austenite transformation under no elastic stress or plastic deformation. These methods will be an enabler for the development and electronic archiving of a quantitative database for process modeling using computer simulation software, and will greatly assist endusers in developing accurate process and product simulations during the thermo-mechanical processing of bar and rod product steels.

Dr. Manish Metha; Dr. Tom Oakwood

2004-04-28T23:59:59.000Z

304

Method for quantitative determination and separation of trace amounts of chemical elements in the presence of large quantities of other elements having the same atomic mass  

DOE Patents (OSTI)

Photoionization via autoionizing atomic levels combined with conventional mass spectroscopy provides a technique for quantitative analysis of trace quantities of chemical elements in the presence of much larger amounts of other elements with substantially the same atomic mass. Ytterbium samples smaller than 10 ng have been detected using an ArF* excimer laser which provides the atomic ions for a time-of-flight mass spectrometer. Elemental selectivity of greater than 5:1 with respect to lutetium impurity has been obtained. Autoionization via a single photon process permits greater photon utilization efficiency because of its greater absorption cross section than bound-free transitions, while maintaining sufficient spectroscopic structure to allow significant photoionization selectivity between different atomic species. Separation of atomic species from others of substantially the same atomic mass is also described.

Miller, C.M.; Nogar, N.S.

1982-09-02T23:59:59.000Z

305

QUANTITATIVE X-RAY POWDER DIFFRACTION ANALYSES OF CLAYS USING AN ORIENTING INTERNAL STANDARD AND PRESSED DISKS OF BULK SHALE SAMPLES  

E-Print Network (OSTI)

Abstraet--Quantitative analysis of clay minerals by X-ray powder diffraction requires oriented clays in order to increase detection limits of the analyses. This is achieved commonly either by smear or sedimentation techniques; however, these techniques can lead to poor analytical precision when used with an internal standard because they often produce non-homogeneous internal standard-clay mineral mixtures. Compaction of bulk shale material at 8000 psi in an hydraulic press produces preferred orientations comparable to that produced by smear or sedimentation. When used with a suitable platy internal standard which provides an estimate of clay mineral preferred orientation, excellent analytical precision is achieved routinely. Several lines of experimental evidence indicate that 1-5 /tm MoS2 is an ideal orienting internal standard for use with compaction mounts.

R. D. Cody; G. L. Thompson

1976-01-01T23:59:59.000Z

306

Near quantitative agreement of model free DFT- MD predictions with XAFS observations of the hydration structure of highly charged transition metal ions  

Science Conference Proceedings (OSTI)

DFT-MD simulations (PBE96 and PBE0) with MD-XAFS scattering calculations (FEFF9) show near quantitative agreement with new and existing XAFS measurements for a comprehensive series of transition metal ions which interact with their hydration shells via complex mechanisms (high spin, covalency, charge transfer, etc.). This work was supported by the U.S. Department of Energy (DOE), Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences and Biosciences. Pacific Northwest National Laboratory (PNNL) is operated for the U.S. DOE by Battelle. A portion of the research was performed using EMSL, a national scientific user facility sponsored by the U.S. DOE's Office of Biological and Environmental Research and located at Pacific Northwest National Laboratory.

Fulton, John L.; Bylaska, Eric J.; Bogatko, Stuart A.; Balasubramanian, Mahalingam; Cauet, Emilie L.; Schenter, Gregory K.; Weare, John H.

2012-09-20T23:59:59.000Z

307

Quantitative Excited State Spectroscopy of a Single InGaAs Quantum Dot Molecule through Multi-million Atom Electronic Structure Calculations  

E-Print Network (OSTI)

Atomistic electronic structure calculations are performed to study the coherent inter-dot couplings of the electronic states in a single InGaAs quantum dot molecule. The experimentally observed excitonic spectrum [12] is quantitatively reproduced, and the correct energy states are identified based on a previously validated atomistic tight binding model. The extended devices are represented explicitly in space with 15 million atom structures. An excited state spectroscopy technique is presented in which the externally applied electric field is swept to probe the ladder of the electronic energy levels (electron or hole) of one quantum dot through anti-crossings with the energy levels of the other quantum dot in a two quantum dot molecule. Such technique can be applied to estimate the spatial electron-hole spacing inside the quantum dot molecule as well as to reverse engineer the quantum dot geometry parameters such as the quantum dot separation. Crystal deformation induced piezoelectric effects have been discus...

Usman, Muhammad; Ryu, Hoon; Ahmed, Shaikh; Boykin, Timothy; Klimeck, Gerhard

2011-01-01T23:59:59.000Z

308

The efficacy of marker-assisted-selection for grain mold resistance in sorghum  

E-Print Network (OSTI)

Five breeding populations were created by crossing elite U.S. sorghum parental lines (RTx430, RTx436, BTx631, BTx635, and Tx2903) with 'Sureño', a dual purpose grain mold resistant sorghum cultivar. Molecular markers associated with five previously-reported quantitative trait loci (QTL) for grain mold resistance originating in 'Sureño' were used to determine if their presence enhanced selection for grain mold resistance in these populations. The allelic status of 87 F4 lines, with respect to these QTL, was determined using both simple sequence repeats (SSR) and amplified fragment length polymorphism (AFLP) markers. All 87 F4:5 lines and their parental lines, were evaluated for grain mold resistance in replicated trials in eight diverse environments in South and Central Texas during the summer of 2002. The effects of each allele from the grain mold resistant parent 'Sureño' were determined across and within all five populations, within individual environments, and in each population x environment combination. With a few exceptions, the QTL were effective in reducing grain mold susceptibility only within the RTx430/Sureño progeny, the identical cross that was used in the original mapping study. The results indicate that while that these alleles do confer additional grain mold resistance, they are only selectable in the original mapping population. This fact limits their potential usefulness in an applied breeding program.

Franks, Cleve Douglas

2003-12-01T23:59:59.000Z

309

A resilience assessment framework for infrastructure and economic systems : quantitative and qualitative resilience analysis of petrochemical supply chains to a hurricane.  

SciTech Connect

In recent years, the nation has recognized that critical infrastructure protection should consider not only the prevention of disruptive events, but also the processes that infrastructure systems undergo to maintain functionality following disruptions. This more comprehensive approach has been termed critical infrastructure resilience (CIR). Given the occurrence of a particular disruptive event, the resilience of a system to that event is the system's ability to efficiently reduce both the magnitude and duration of the deviation from targeted system performance levels. Sandia National Laboratories (Sandia) has developed a comprehensive resilience assessment framework for evaluating the resilience of infrastructure and economic systems. The framework includes a quantitative methodology that measures resilience costs that result from a disruption to infrastructure function. The framework also includes a qualitative analysis methodology that assesses system characteristics that affect resilience in order to provide insight and direction for potential improvements to resilience. This paper describes the resilience assessment framework. This paper further demonstrates the utility of the assessment framework through application to a hypothetical scenario involving the disruption of a petrochemical supply chain by a hurricane.

Ehlen, Mark Andrew; Vugrin, Eric D.; Warren, Drake E.

2010-03-01T23:59:59.000Z

310

Departures from local thermodynamic equilibrium in cutting arc plasmas derived from electron and gas density measurements using a two-wavelength quantitative Schlieren technique  

SciTech Connect

A two-wavelength quantitative Schlieren technique that allows inferring the electron and gas densities of axisymmetric arc plasmas without imposing any assumption regarding statistical equilibrium models is reported. This technique was applied to the study of local thermodynamic equilibrium (LTE) departures within the core of a 30 A high-energy density cutting arc. In order to derive the electron and heavy particle temperatures from the inferred density profiles, a generalized two-temperature Saha equation together with the plasma equation of state and the quasineutrality condition were employed. Factors such as arc fluctuations that influence the accuracy of the measurements and the validity of the assumptions used to derive the plasma species temperature were considered. Significant deviations from chemical equilibrium as well as kinetic equilibrium were found at elevated electron temperatures and gas densities toward the arc core edge. An electron temperature profile nearly constant through the arc core with a value of about 14000-15000 K, well decoupled from the heavy particle temperature of about 1500 K at the arc core edge, was inferred.

Prevosto, L.; Mancinelli, B. [Grupo de Descargas Electricas, Departamento Ing. Electromecanica, Facultad Regional Venado Tuerto (UTN), Laprida 651, Venado Tuerto 2600, Santa Fe (Argentina); Artana, G. [Laboratorio de Fluidodinamica, Departamento Ing. Mecanica, Facultad de Ingenieria (UBA), Paseo Colon 850, C1063ACV, Buenos Aires (Argentina); Kelly, H. [Grupo de Descargas Electricas, Departamento Ing. Electromecanica, Facultad Regional Venado Tuerto (UTN), Laprida 651, Venado Tuerto 2600, Santa Fe (Argentina); Departamento de Fisica, Facultad de Ciencias Exactas y Naturales (UBA), Instituto de Fisica del Plasma (CONICET), Ciudad Universitaria, Pab. I, 1428 Buenos Aires (Argentina)

2011-03-15T23:59:59.000Z

311

Quantitative characterization of the protein contents of the exocrine pancreatic acinar cell by soft x-ray microscopy and advanced digital imaging methods  

Science Conference Proceedings (OSTI)

The study of the exocrine pancreatic acinar cell has been central to the development of models of many cellular processes, especially of protein transport and secretion. Traditional methods used to examine this system have provided a wealth of qualitative information from which mechanistic models have been inferred. However they have lacked the ability to make quantitative measurements, particularly of the distribution of protein in the cell, information critical for grounding of models in terms of magnitude and relative significance. This dissertation describes the development and application of new tools that were used to measure the protein content of the major intracellular compartments in the acinar cell, particularly the zymogen granule. Soft x-ray microscopy permits image formation with high resolution and contrast determined by the underlying protein content of tissue rather than staining avidity. A sample preparation method compatible with x-ray microscopy was developed and its properties evaluated. Automatic computerized methods were developed to acquire, calibrate, and analyze large volumes of x-ray microscopic images of exocrine pancreatic tissue sections. Statistics were compiled on the protein density of several organelles, and on the protein density, size, and spatial distribution of tens of thousands of zymogen granules. The results of these measurements, and how they compare to predictions of different models of protein transport, are discussed.

Loo Jr., Billy W.

2000-06-09T23:59:59.000Z

312

Immunochemical approach to indoor aeroallergen quantitation with a new volumetric air sampler: studies with mite, roach, cat, mouse, and guinea pig antigens  

SciTech Connect

We describe a new high-volume air sampler for determining antigen concentrations in homes and illustrate its use for quantitating airborne house dust mite, cat, cockroach, mouse, and guinea pig antigens. The concentration of house dust-mite antigen was similar from houses in Rochester, Minn. and tenement apartments in Harlem, N. Y., but cockroach and mouse urinary proteins were present only in Harlem. The amount of cat or guinea pig antigen varied as expected with the number of pets in the home. In calm air the airborne concentration of mite and cat antigen was similar throughout the house but increased greatly in a bedroom when bedding was changed. In calm air most of the cat and mite antigens were associated with respirable particles less than 5 microns mean aerodynamic mass diameter, but in air sampled after the bedding was changed, more cat antigen was found in particles greater than 5 microns. The apparatus and technique described can provide objective data concerning the magnitude and the relative distribution and duration of suspended particles of defined sizes, which contain allergen activity.

Swanson, M.C.; Agarwal, M.K.; Reed, C.E.

1985-11-01T23:59:59.000Z

313

Improved quantitative medical CT imaging  

Science Conference Proceedings (OSTI)

... which will in turn reduce the error in measurement of Validate that the phantom developed by NIST is an acceptable model for the human thorax in ...

2011-10-03T23:59:59.000Z

314

The NIST Quantitative Infrared Database  

Science Conference Proceedings (OSTI)

... Dimethoxybenzidine 156627 Calcium cyanamide 60117 Dimethyl aminoazobenzene ... Quinone 7664393 Hydrogen fluoride 100425 Styrene ...

2007-04-27T23:59:59.000Z

315

Quantitative methods and gender inequalities  

E-Print Network (OSTI)

-related changes in time-use. The interesting family transitions for the purpose of studying the relationship between family conditions and individuals’ time-use are relatively rare ones. Using the British Household Panel Study, which follows more than 5000...

Scott, Jacqueline

316

QUALITATIVE AND QUANTITATIVE DETERMINATION OF ...  

Science Conference Proceedings (OSTI)

Jul 20, 2012 ... Product In Stock ... The Mg- Prefil method can be applied in any casthouse or foundry, taking liquid metal samples at various stages of the ...

317

Quantitative Excited State Spectroscopy of a Single InGaAs Quantum Dot Molecule through Multi-million Atom Electronic Structure Calculations  

E-Print Network (OSTI)

Atomistic electronic structure calculations are performed to study the coherent inter-dot couplings of the electronic states in a single InGaAs quantum dot molecule. The experimentally observed excitonic spectrum [12] is quantitatively reproduced, and the correct energy states are identified based on a previously validated atomistic tight binding model. The extended devices are represented explicitly in space with 15 million atom structures. An excited state spectroscopy technique is presented in which the externally applied electric field is swept to probe the ladder of the electronic energy levels (electron or hole) of one quantum dot through anti-crossings with the energy levels of the other quantum dot in a two quantum dot molecule. This technique can be applied to estimate the spatial electron-hole spacing inside the quantum dot molecule as well as to reverse engineer quantum dot geometry parameters such as the quantum dot separation. Crystal deformation induced piezoelectric effects have been discussed in the literature as minor perturbations lifting degeneracies of the electron excited (P and D) states, thus affecting polarization alignment of wave function lobes for III-V Heterostructures such as single InAs/GaAs quantum dots. In contrast this work demonstrates the crucial importance of piezoelectricity to resolve the symmetries and energies of the excited states through matching the experimentally measured spectrum in an InGaAs quantum dot molecule under the influence of an electric field. Both linear and quadratic piezoelectric effects are studied for the first time for a quantum dot molecule and demonstrated to be indeed important. The net piezoelectric contribution is found to be critical in determining the correct energy spectrum, which is in contrast to recent studies reporting vanishing net piezoelectric contributions.

Muhammad Usman; Yui-Hong Matthias Tan; Hoon Ryu; Shaikh S. Ahmed; Hubert Krenner; Timothy B. Boykin; Gerhard Klimeck

2010-08-18T23:59:59.000Z

318

Quantitative Discomanometry: Correlation of Intradiscal Pressure Values to Pain Reduction in Patients With Intervertebral Disc Herniation Treated With Percutaneous, Minimally Invasive, Image-Guided Techniques  

Science Conference Proceedings (OSTI)

Purpose: To illustrate quantitative discomanometry's (QD) diagnostic efficacy and predictive value in discogenic-pain evaluation in a prospective study correlating intradiscal pressure values with pain reduction after percutaneous image-guided technique (i.e., percutaneous decompression, PD). Materials and Methods: During the last 3 years, 36 patients [21 male and 15 female (mean age 36 {+-} 5.8 years)] with intervertebral disc hernia underwent QD before PD. Under absolute sterilization and fluoroscopy, a mixture of contrast medium and normal saline (3:1 ratio) was injected. A discmonitor performed a constant rate injection and recorded pressure and volume values, thus producing the relative pressure-volume curve. PD was then performed. Pain reduction and improved mobility were recorded at 3, 12, and 24 months after PD using clinical evaluation and a numeric visual scale (NVS; 0 to 10 units). Results: Mean pain values of 7.5 {+-} 1.9 (range 4 to 8) NVS units were recorded before PD; these decreased to 2.9 {+-} 2.44 at 3 months, 1.0 {+-} 1.9 at 12 months, and 1.0 {+-} 1.9 NVS units at 24 months after PD. Recorded correlations (pressure, volume, significant pain-reduction values) with bilateral statistical significance included a maximum injected volume of 2.4 ml (p = 0.045), P{sub o} 4 NVS units) after PD. No complications were noted. Conclusions: QD is an efficient technique that may have predictive value for discogenic pain evaluation. It might serve as a useful tool for patient selection for intervertebral disc therapies.

Filippiadis, Dimitrios K., E-mail: dfilippiadis@yahoo.gr; Mazioti, A., E-mail: argyromazioti@yahoo.gr; Papakonstantinou, O., E-mail: sogofianol@gmail.com; Brountzos, E., E-mail: ebrountz@med.uoa.gr [University General Hospital 'Attikon', Second Radiology Department (Greece); Gouliamos, A., E-mail: agouliam@med.uoa.gr [University General Hospital 'Areteion', First Radiology Department (Greece); Kelekis, N., E-mail: kelnik@med.uoa.gr; Kelekis, A., E-mail: akelekis@med.uoa.gr [University General Hospital 'Attikon', Second Radiology Department (Greece)

2012-10-15T23:59:59.000Z

319

Adaptive trait Characteristics that improve an individual's survival and fitness.  

E-Print Network (OSTI)

heavier particles (gravel, boulders) rolled along the bottom; the part of the load the long term. Channel morphology The physical dimension, shape, form, pattern, profile, and structure dimension, pattern, and profile without either aggrading or degrading. Channelization The straightening

320

Does endopolyploidy influence functional traits of Solidago altissima leaves?  

E-Print Network (OSTI)

with light directly from the power compact bulbs inside the chamber, the other with the same light filtered is in response to varying light quality, as instances of endopolyploidy have been correlated with a decrease in light quality. I propose an experiment to examine the occurrence of endopolyploidy though ontogeny

Weiblen, George D

Note: This page contains sample records for the topic "quantitative trait loci" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


321

A Proposal for Collaborative Ontology Editor for Animal Trait Ontology  

E-Print Network (OSTI)

such as public, private and protected. Reasons to use package in ATO include: ­ Package serves as organization controlled and traced. Packages is the structural unit in the design phase; when the ontology is released, the user does not necessarily aware of packages. From the view of end user, ATO has similar structure

Bao, Jie

322

EVALUATION OF NOVEL INPUT OUTPUT TRAITS IN SORGHUM THROUGH BIOTECHNOLOGY.  

E-Print Network (OSTI)

??Sorghum [Sorghum bicolor (L.) Moench] is the fifth most important cereal crop world-wide as well as an important source of feed, fiber and biofuel. It… (more)

Mall, Tejinder K.

2010-01-01T23:59:59.000Z

323

Analysis of pharmacogenetic traits in two distinct South African populations  

E-Print Network (OSTI)

PUBLICATIONS 1479 –7364. HUMAN GENOMICS. VOL 5. NO 4. 265 –PUBLICATIONS 1479– 7364. HUMAN GENOMICS. VOL 5. NO 4. 265 –PUBLICATIONS 1479– 7364. HUMAN GENOMICS. VOL 5. NO 4. 265 –

Ikediobi, Ogechi; Aouizerat, Bradley; Xiao, Yuanyuan; Gandhi, Monica; Gebhardt, Stefan; Warnich, Louise

2011-01-01T23:59:59.000Z

324

Please cite this article in press as: White III, R.A., et al., Digital PCR provides absolute quantitation of viral load for an occult RNA virus. J. Virol. Methods (2011), doi:10.1016/j.jviromet.2011.09.017  

E-Print Network (OSTI)

quantitation of viral load for an occult RNA virus. J. Virol. Methods (2011), doi:10.1016/j.jviromet.2011.elsevier.com/locate/jviromet Digital PCR provides absolute quantitation of viral load for an occult RNA virus1 Richard Allen White IIIa-C14 LNA probes15 Microfluidics16 Occult virus17 In vitro transcription18 CV/SEM19 a b s t r a c

Quake, Stephen R.

325

Evidence of novel fine-scale structural variation at autism spectrum disorder candidate loci  

E-Print Network (OSTI)

P, Turunen JA, Makkonen I, Riikonen R, Nieminen-von Wendt T,von Wendt L, Peltonen L, Jarvela I: Analysis of four

2012-01-01T23:59:59.000Z

326

TANGENT CUT LOCI ON SURFACES A. FIGALLI, L. RIFFORD, AND C. VILLANI  

E-Print Network (OSTI)

, v) := max t 0; (expx(sv))0st is a minimizing geodesic . Then for any x M, we let TCL(x) = tangent; 0 t TCL(x) is compact and coincides with the boundary of the open set I(x). Finally, the cut locus of x may be defined as cut(x) := expx TCL(x) . Many works [2, 8

Villani, Cédric

327

Signatures of selection in loci governing major colour patterns in Heliconius butterflies and related species  

E-Print Network (OSTI)

original format “HM000... ”. 2Total bps: total length, in basepairs, of the annotated gene. 3Lineage-based: Heliconius lineage-based background ? estimates (’branch model = 0 ’ in COD EML) using BAC sequences of three species ( H. melpomene , H . erato , H... original format “HM000... ”. 2Total bps: total length, in basepairs, of the annotated gene. 3Lineage-based: Heliconius lineage-based background ? estimates (’branch model = 0 ’ in COD EML) using BAC sequences of three species ( H. melpomene , H . erato , H...

Wu, Grace C; Joron, Mathieu; Jiggins, Chris D

2010-11-29T23:59:59.000Z

328

Comparative genomics of Lbx loci reveals conservation of identical Lbx ohnologs in bony vertebrates  

E-Print Network (OSTI)

Abbreviation Species Current Nomenclature Proposed Nomenclature ID Ag dpcd Anopheles gambiae dpcd XP_307420.3 Bf dpcd Branchiosto ma floridae dpcd estExt_fgenesh2_pm.C_1420 005 Dr chr11 Danio rerio Dpcd NP_001038842.1 Fr s62 Fugu rubripes Dpcd...

Wotton, Karl R; Weierud, Frida K; Dietrich, Susanne; Lewis, Katharine E

2008-06-09T23:59:59.000Z

329

Study of familial breast cancer: identifying additional breast cancer susceptibility loci;.  

E-Print Network (OSTI)

??Breast cancer is a serious public health concern and despite intensive research, the etiology of breast cancer is poorly understood. Known risk factors explain only… (more)

Allen-Brady, Kristina Lisa

2006-01-01T23:59:59.000Z

330

Appendix 4-One-locus Hardy-Weinberg test p-values loci ...  

Science Conference Proceedings (OSTI)

... 0.37 AMW 0.50 0.34 0.88 0.07 0.14 0.66 1.00 1.00 0.18 0.81 ANG 0.55 0.60 0.76 0.85 0.79 0.45 0.83 1.00 0.86 0.54 ASH ...

2012-01-30T23:59:59.000Z

331

Genetic Loci Related to Kernel Quality Differences between a Soft and a Hard Wheat Cultivar  

E-Print Network (OSTI)

ABSTRACT processing and end-use characteristics, which depend Hybridizations between hard and soft wheat types could be a source on protein hydration and development through mixing. of novel variation for wheat quality improvement. This study was con- Hard wheat is generally used for making bread-type ducted to identify genomic regions related to differences in milling and products, and soft wheat is generally preferred for baking quality between a soft and a hard cultivar of hexaploid wheat pastry-type products. Hard grain requires more energy (Triticum aestivum L.). A population of 101 double-haploid lines was to be reduced to flour than soft grain, and its starch generated from a cross between Grandin, a hard spring wheat variety, and AC Reed, a soft spring wheat variety. The genetic map included 320 markers in 43 linkage groups and spanned 3555 cM. Quadrumat-milled flour yield, softness equivalent, flour protein content and alkaline water retention capacity were evaluated for three locations and one year, and Allis-Chalmers milling, mixograph, and cookie baking tests were completed without replication. The effect of qualitative variation for kernel texture, caused by the segregation of the Hardness gene, was granules are damaged more during milling. Damaged

Flávio Breseghello; Patrick L. Finney; Charles Gaines; Lonnie Andrews; James Tanaka; Gregory Penner; Mark E. Sorrells

2005-01-01T23:59:59.000Z

332

Evidence of novel fine-scale structural variation at autism spectrum disorder candidate loci  

E-Print Network (OSTI)

Hussman Institute for Human Genomics, University of MiamiHussman Institute for Human Genomics, University of MiamiHIHG: Hussman Institute of Human Genomics; IQ: Intelligence

2012-01-01T23:59:59.000Z

333

Quantitative LEED I-V and ab initio study of the Si(111)-3x2-Sm surface structure and the missing half-order spots in the 3x1 diffraction pattern  

SciTech Connect

We have used low-energy electron diffraction (LEED) I-V analysis and ab initio calculations to quantitatively determine the honeycomb chain model structure for the Si(111)-3x2-Sm surface. This structure and a similar 3x1 recontruction have been observed for many alkali-earth and rare-earth metals on the Si(111) surface. Our ab initio calculations show that there are two almost degenerate sites for the Sm atom in the unit cell, and the LEED I-V analysis reveals that an admixture of the two in a ratio that slightly favors the site with the lower energy is the best match to experiment. We show that the I-V curves are insensitive to the presence of the Sm atom and that this results in a very low intensity for the half-order spots, which might explain the appearance of a 3x1 LEED pattern produced by all of the structures with a 3x2 unit cell.

Eames, C.; Probert, M. I. J.; Tear, S. P. [Department of Physics, University of York, York YO10 5DD (United Kingdom)

2007-05-15T23:59:59.000Z

334

Quantitative analysis and modeling of microembolic phenomena  

E-Print Network (OSTI)

This thesis explores parameters that govern microvascular occlusion secondary to embolic phenomenon. Bulk and individual properties of microembolic particles were characterized using light microscopy, SEM and optically-based ...

Feldstein, Michael J. (Michael Jordan)

2006-01-01T23:59:59.000Z

335

Quantitative Assessment of Robot-generated Maps  

Science Conference Proceedings (OSTI)

... in- nocuous daily chores around the household to potentially ... as speed and memory consumption, are easy ... The alignment energy for this process is ...

2009-03-06T23:59:59.000Z

336

Spatially Resolved Quantitative Mapping for Thermal ...  

Data from this method are important for a ... Energy Analysis ... Technology Marketing Summary ORNL researchers invented a method that uses band ...

337

ARTICLE IN PRESS Journal of Quantitative Spectroscopy &  

E-Print Network (OSTI)

www.elsevier.com/locate/jqsrt Towards linearization of atmospheric radiative transfer in spherical geometry

Holger H. Walter; Jochen L

2004-01-01T23:59:59.000Z

338

Quantitative troubleshooting of industrial exhaust ventilation systems  

SciTech Connect

This article proposes two troubleshooting tools that may allow precise and accurate assessment of changes to ventilation systems of any type. Both are useful in discovering and quantifying most modifications that affect the distribution of airflows among the branches and static pressures throughout the system. The approaches are derived from energy balance considerations, using power loss coefficients (X) computed for any contiguous section of the system from the duct velocities and static pressures measured at that section`s inlets and outlets. The value of X for a given portion of the system should be nearly constant with changes in airflow and with modifications to other portions of the system. Responsiveness to local modifications and insensitivity to changes elsewhere in the system - including gross changes in fan performance - make X coefficients a valuable troubleshooting tool. Static pressure ratios within a given branch are functionally related to ratios of X coefficients. Therefore, they vary with modifications to the branch and are highly insensitive to changes outside that branch. Unlike X coefficients, determination of static pressure ratios does not require velocity traverses, making them faster and easier to determine than X values. On the other hand, values of X are more universally applicable and have direct physical significance. Use of both static pressure ratios and X coefficients are described in a suggested troubleshooting procedure. Systematic measurement errors have surprisingly little impact on the usefulness of values of X or static pressure ratios. The major impediment to using either tool is the necessity for {open_quotes}baseline{close_quotes} measurements, which are often unavailable. On the other hand, a baseline for future comparisons can be created piecemeal, beginning at any time and extending over any period of time. 11 refs., 8 figs., 8 tabs.

Guffey, S.E. [Univ. of Washington, Seattle, WA (United States)

1994-04-01T23:59:59.000Z

339

Geothermal Reconnaissance From Quantitative Analysis Of Thermal...  

Open Energy Info (EERE)

Author(s): K. Watson Published: Proceedings of the ninth international symposium on remote sensing of environment, April 15-19, p. 1919-1932., 1974 Document Number:...

340

Evaluating Model Abstractions: A Quantitative Approach  

E-Print Network (OSTI)

An \\evaluation " approach devised for an inductive reasoning system called Logic-based Discrete-event Inductive Reasoner is the focus of this paper. The underlying inductive reasoning methodology utilizes abstractions as its primary means to deal with lack ofknowledge. Based on abstractions and their treatments as assumptions, the Logic-based Discrete-event Inductive Reasoning system allows non-monotonic predictions. The evaluation approach takes into account explicitly the role of abstractions employed in non-monotonically derived multiple predictions. These predictions are ranked according to the type and number of abstractions used. The proposed evaluation approach is also discussed in relation to the dichotomy of model validation and simulation correctness.

Hessam S. Sarjoughian; Bernard P. Zeigler; Francois E. Cellier

1998-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "quantitative trait loci" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


341

Quantitative spectroscopy for detection of cervical dysplasia  

E-Print Network (OSTI)

The current clinical standard for cervical cancer diagnosis is colposcopy, a procedure that involves visual inspection and biopsy of at-risk tissue, followed by histopathology. The major objective of colposcopy is detection ...

Mirkovi?, Jelena, Ph. D. Massachusetts Institute of Technology

2009-01-01T23:59:59.000Z

342

Microfluidics for optics and quantitative cell biology  

E-Print Network (OSTI)

E. European Journal of Cell Biology 2006 . Thompson, D. M. ;S. H. Journal of Cell Biology 1977 , 75 , 606-616. Zicha,Physiology and Plant Molecular Biology 1997 , 48 , 493-523.

Campbell, James Kyle

2008-01-01T23:59:59.000Z

343

An empirical analysis of quantitative trading strategies  

E-Print Network (OSTI)

Along with the increasing computing power, growing availability of various data streams, introduction of the electronic exchanges, decreasing trading costs and heating-up competition in financial investment industry, ...

Aiuchi, Masaharu

2008-01-01T23:59:59.000Z

344

Quantitative nondestructive testing using Infrared Thermography  

E-Print Network (OSTI)

blades. Technical report, Sandia National Laboratory,Turbine Reliability Workshop. Sandia, 2009. [86] M. Rumsey,Rumsey and Dennis Roach of Sandia National Laboratories for

Manohar, Arun

2012-01-01T23:59:59.000Z

345

Quantitative comparison of passive solar simulation codes  

DOE Green Energy (OSTI)

Several members of the Systems Simulation and Economic Analysis (SS/EA) Working Group have participated in a software-software comparison of passive solar simulation codes. The problems selected and defined by the Los Alamos Scientific Laboratory (LASL) for analysis include both a vented and an unvented Trombe wall and a direct gain building. The individuals, organizations, and associated computer models involved in this exercise are Byron Wynn, Colorado State University (CSU) (FREHEAT); Larry Palmiter, National Center for Appropriate Technology (NCAT) (SUNCAT); Bill Beckman, the University of Wisconsin (WIS) (TRNSYS); Bill Wray, LASL (PASOLE, SUNSPOT); and John Moore, LASL (DOE-2). Each of these organizations submitted simulation results to LASL, where a comparative analysis was conducted. Excellent agreement was achieved on annual auxiliary heat loads, but several detailed heat fluxes within the structures showed significant scatter, as did both the ventilation and auxiliary cooling.

Wray, W.O.

1980-01-01T23:59:59.000Z

346

Quantitative analysis of the economically recoverable resource  

Science Conference Proceedings (OSTI)

The objective of this study is to obtain estimates of the economically recoverable gas in the Appalachian Basin. The estimates were obtained in terms of a probability distribution, which quantifies the inherent uncertainty associated with estimates where geologic and production uncertainties prevail. It is established that well productivity on a county and regional basis is lognormally distributed, and the total recoverable gas is Normally distributed. The expected (mean), total economically recoverable gas is 20.2 trillion cubic feet (TCF) with a standard deviation of 1.6 TCF, conditional on the use of shooting technology on 160-acre well-spacing. From properties of the Normal distribution, it is seen that a 95 percent probability exists for the total recoverable gas to lie between 17.06 and 23.34 TCF. The estimates are sensitive to well spacings and the technology applied to a particular geologic environment. It is observed that with smaller well spacings - for example, at 80 acres - the estimate is substantially increased, and that advanced technology, such as foam fracturing, has the potential of significantly increasing gas recovery. However, the threshold and optimum conditions governing advanced exploitation technology, based on well spacing and other parameters, were not analyzed in this study. Their technological impact on gas recovery is mentioned in the text where relevant; and on the basis of a rough projection an additional 10 TCF could be expected with the use of foam fracturing on wells with initial open flows lower than 300 MCFD. From the exploration point of view, the lognormal distribution of well productivity suggests that even in smaller areas, such as a county basis, intense exploration might be appropriate. This is evident from the small tail probabilities of the lognormal distribution, which represent the small number of wells with relatively very high productivity.

Pulle, C.V.; Seskus, A.P.

1981-05-01T23:59:59.000Z

347

Quantitative Rietveld XRD Mineralogy of Copper and ...  

Science Conference Proceedings (OSTI)

... Mylar Standard analyzed daily on NIR ? AXN Ore Standard (Granite) analyzed daily on each XRD ... Page 22. AXN XRD Granite Ore Standard ...

2013-06-07T23:59:59.000Z

348

Quantitative, Cell-based Immunofluorescence Assays  

Science Conference Proceedings (OSTI)

... Bhadriraju, K., Elliott, JT, Nguyen, M., Plant, AL, 2007, Quantifying myosin light chain phosphorylation in single adherent cells with automated ...

2012-10-10T23:59:59.000Z

349

Review of Quantitative Software Reliability Methods  

Science Conference Proceedings (OSTI)

The current U.S. Nuclear Regulatory Commission (NRC) licensing process for digital systems rests on deterministic engineering criteria. In its 1995 probabilistic risk assessment (PRA) policy statement, the Commission encouraged the use of PRA technology in all regulatory matters to the extent supported by the state-of-the-art in PRA methods and data. Although many activities have been completed in the area of risk-informed regulation, the risk-informed analysis process for digital systems has not yet been satisfactorily developed. Since digital instrumentation and control (I&C) systems are expected to play an increasingly important role in nuclear power plant (NPP) safety, the NRC established a digital system research plan that defines a coherent set of research programs to support its regulatory needs. One of the research programs included in the NRC's digital system research plan addresses risk assessment methods and data for digital systems. Digital I&C systems have some unique characteristics, such as using software, and may have different failure causes and/or modes than analog I&C systems; hence, their incorporation into NPP PRAs entails special challenges. The objective of the NRC's digital system risk research is to identify and develop methods, analytical tools, and regulatory guidance for (1) including models of digital systems into NPP PRAs, and (2) using information on the risks of digital systems to support the NRC's risk-informed licensing and oversight activities. For several years, Brookhaven National Laboratory (BNL) has worked on NRC projects to investigate methods and tools for the probabilistic modeling of digital systems, as documented mainly in NUREG/CR-6962 and NUREG/CR-6997. However, the scope of this research principally focused on hardware failures, with limited reviews of software failure experience and software reliability methods. NRC also sponsored research at the Ohio State University investigating the modeling of digital systems using dynamic PRA methods. These efforts, documented in NUREG/CR-6901, NUREG/CR-6942, and NUREG/CR-6985, included a functional representation of the system's software but did not explicitly address failure modes caused by software defects or by inadequate design requirements. An important identified research need is to establish a commonly accepted basis for incorporating the behavior of software into digital I&C system reliability models for use in PRAs. To address this need, BNL is exploring the inclusion of software failures into the reliability models of digital I&C systems, such that their contribution to the risk of the associated NPP can be assessed.

Chu, T.L.; Yue, M.; Martinez-Guridi, M.; Lehner, J.

2010-09-17T23:59:59.000Z

350

Quantitative Assessment of Distributed Energy Resource Benefits  

Science Conference Proceedings (OSTI)

Distributed energy resources (DER) offer many benefits, some of which are readily quantified. Other benefits, however, are less easily quantifiable because they may require site-specific information about the DER project or analysis of the electrical system to which the DER is connected. The purpose of this study is to provide analytical insight into several of the more difficult calculations, using the PJM power pool as an example. This power pool contains most of Pennsylvania, New Jersey, Maryland, and Delaware. The techniques used here could be applied elsewhere, and the insights from this work may encourage various stakeholders to more actively pursue DER markets or to reduce obstacles that prevent the full realization of its benefits. This report describes methodologies used to quantify each of the benefits listed in Table ES-1. These methodologies include bulk power pool analyses, regional and national marginal cost evaluations, as well as a more traditional cost-benefit approach for DER owners. The methodologies cannot however determine which stakeholder will receive the benefits; that must be determined by regulators and legislators, and can vary from one location to another.

Hadley, S.W.

2003-05-22T23:59:59.000Z

351

Projective behaviour of nur: quantitative experimental research  

Science Conference Proceedings (OSTI)

The paper presents the results of the experiment on the projective meaning of nur (German: only). The data from German shows that the prejacent of nur projects easily out of counterfactual if-clauses, whereas its projective ... Keywords: counterfactual and indicative conditionals, presupposition projection, semantics of nur (only) and auch (also)

Agata Maria Renans

2011-12-01T23:59:59.000Z

352

Quantitative Simulation of Surface Segregation Phenomena in ...  

Science Conference Proceedings (OSTI)

Atomistic modeling of thermodynamic properties of Pu-Ga alloys based on the Invar ... Resources for the selection and use of interatomic potentials in atomistic  ...

353

Quantitative analysis of subcellular biomechanics and mechanotransduction  

E-Print Network (OSTI)

Biological cells such as endothelial or muscle cells respond to mechanical stimulation with activation of specific intracellular and extracellular signaling pathways and cytoskeletal remodeling, a process termed ...

Lammerding, Jan, 1974-

2004-01-01T23:59:59.000Z

354

201_07 Qualitative and Quantitative Analysis  

Science Conference Proceedings (OSTI)

AOCS Press, Urbana, IL 61802 ©2005 by AOCS Press. All rights reserved. No part of this PDF may be repro-

355

Quantitative luminescence imaging system - Energy Innovation ...  

The QLIS images and quantifies low-level chemiluminescent reactions in an electromagnetic field. It is capable of real time nonperturbing measurement and simultaneous ...

356

Quantitative Interpretation of Laser Ceilometer Intensity Profiles  

Science Conference Proceedings (OSTI)

The authors have used a commercially available laser ceilometer to measure vertical profiles of the optical extinction in rain. This application requires special signal processing to correct the raw data for the effects of receiver noise, high-...

R. R. Rogers; M-F. Lamoureux; L. R. Bissonnette; R. M. Peters

1997-06-01T23:59:59.000Z

357

Quantitative Analyses of Anaerobic Wastewater Treatment Processes  

E-Print Network (OSTI)

-generation biodiesel, ethanol, or biogas to the transport sector to be blended with fossil fuels. Still under

Timmer, Jens

358

Quantitative approaches to probe the acetylproteome  

E-Print Network (OSTI)

Lysine acetylation is a prevalent post-translational modification whose multi-varied biological roles have recently emerged. While having all the necessary components of a signaling network, lysine acetylation studies have ...

Bryson, Bryan David

2013-01-01T23:59:59.000Z

359

Empirical bayes analysis of quantitative proteomics experiments  

E-Print Network (OSTI)

Background: Advances in mass spectrometry-based proteomics have enabled the incorporation of proteomic data into systems approaches to biology. However, development of analytical methods has lagged behind. Here we describe ...

Golub, Todd R.

360

Quantitative analysis of heart rate variability  

Science Conference Proceedings (OSTI)

In the modern industrialized countries every year several hundred thousands of people die due to sudden cardiac death. The individual risk for this sudden cardiac death cannot be defined precisely by common available

J. Kurths; A. Voss; P. Saparin; A. Witt; H. J. Kleiner

1995-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "quantitative trait loci" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


361

Quantitative Model of the Cerro Prieto Field  

DOE Green Energy (OSTI)

A three-dimensional model of the Cerro Prieto geothermal field, Mexico, is under development. It is based on an updated version of LBL's hydrogeologic model of the field. It takes into account major faults and their effects on fluid and heat flow in the system. First, the field under natural state conditions is modeled. The results of this model match reasonably well observed pressure and temperature distributions. Then, a preliminary simulation of the early exploitation of the field is performed. The results show that the fluid in Cerro Prieto under natural state conditions moves primarily from east to west, rising along a major normal fault (Fault H). Horizontal fluid and heat flow occurs in a shallower region in the western part of the field due to the presence of permeable intergranular layers. Estimates of permeabilities in major aquifers are obtained, and the strength of the heat source feeding the hydrothermal system is determined.

Halfman, S.E.; Lippmann, M.J.; Bodvarsson, G.S.

1986-01-21T23:59:59.000Z

362

Quantitative model of the Cerro Prieto field  

DOE Green Energy (OSTI)

A three-dimensional model of the Cerro Prieto geothermal field, Mexico, is under development. It is based on an updated version of LBL's hydrogeologic model of the field. It takes into account major faults and their effects on fluid and heat flow in the system. First, the field under natural state conditions is modeled. The results of this model match reasonably well observed pressure and temperature distributions. Then, a preliminary simulation of the early exploitation of the field is performed. The results show that the fluid in Cerro Prieto under natural state conditions moves primarily from east to west, rising along a major normal fault (Fault H). Horizontal fluid and heat flow occurs in a shallower region in the western part of the field due to the presence of permeable intergranular layers. Estimates of permeabilities in major aquifers are obtained, and the strength of the heat source feeding the hydrothermal system is determined.

Halfman, S.E.; Lippmann, M.J.; Bodvarsson, G.S.

1986-03-01T23:59:59.000Z

363

Changes in salivary gland function after radiotherapy of head and neck tumors measured by quantitative pertechnetate scintigraphy: Comparison of intensity-modulated radiotherapy and conventional radiation therapy with and without Amifostine  

Science Conference Proceedings (OSTI)

Purpose: The aim of this study was to compare changes in salivary gland function after intensity-modulated radiotherapy (IMRT) and conventional radiotherapy (RT), with or without Amifostine, for tumors of the head-and-neck region using quantitative salivary gland scintigraphy (QSGS). Methods and Materials: A total of 75 patients received pre- and post-therapeutic QSGS to quantify the salivary gland function. In all, 251 salivary glands were independently evaluated. Changes in the maximum uptake ({delta}U) and relative excretion rate ({delta}F) both pre- and post-RT were determined to characterize radiation-induced changes in the salivary gland function. In addition, dose-response curves were calculated. Results: In all groups, maximum uptake and relative excretion rate were reduced after RT ({delta}U {glands, the reduction was smaller for the IMRT-low than for the IMRT-high group. For the Amifostine-high and the conventional group the difference was significant only for one parameter ({delta}U, parotid and submandibular glands, p gland excretion rate of more than 50%,' the dose-response curves yielded D{sub 50}-values of 34.2 {+-} 12.2 Gy for the conventionally treated group and 36.8 {+-} 2.9 Gy for the IMRT group. For the Amifostine group, an increased D{sub 50}-values of 46.3 {+-} 2.3 Gy was obtained. Conclusion: Intensity-modulated RT can significantly reduce the loss of parotid gland function when respecting a certain dose threshold. Conventional RT plus Amifostine prevents reduced salivary gland function only in the patient group treated with <40.6 Gy.

Muenter, Marc W. [Department of Radiation Oncology, University of Heidelberg, Heidelberg (Germany) and Clinical Cooperation Unit Radiation Oncology, German Cancer Research Center, Heidelberg (Germany)]. E-mail: m.muenter@dkfz.de; Hoffner, Simone [Department of Radiation Oncology, St. Vincentius-Klinik Karlsruhe, Karlsruhe (Germany); Department of Nuclear Medicine, University of Heidelberg, Heidelberg (Germany); Hof, Holger [Department of Radiation Oncology, University of Heidelberg, Heidelberg (Germany); Herfarth, Klaus K. [Department of Radiation Oncology, University of Heidelberg, Heidelberg (Germany); Haberkorn, Uwe [Department of Nuclear Medicine, University of Heidelberg, Heidelberg (Germany); Rudat, Volker [Department of Radiation Oncology, St. Josef-Hospital Ruhr-University Bochum, Bochum (Germany); Huber, Peter [Clinical Cooperation Unit Radiation Oncology, German Cancer Research Center, Heidelberg (Germany); Debus, Juergen [Department of Radiation Oncology, University of Heidelberg, Heidelberg (Germany); Karger, Christian P. [Department of Medical Physics in Radiation Oncology, German Cancer Research Center, Heidelberg (Germany)

2007-03-01T23:59:59.000Z

364

NEWTON, Ask a Scientist at Argonne National Labs  

NLE Websites -- All DOE Office Websites (Extended Search)

Albino Gene Loci Albino Gene Loci Name: Gabreal Status: other Grade: 9-12 Location: Outside U.S. Country: USA Date: Spring 2012 Question: What chromosome is albinism located on? Replies: There are actually many different kinds of albinism which occur due to mutations in different genes. In principle, all forms of albinism share a common trait, namely that affected individuals do not produce melanin, the major pigment protein in our skin. However, there are a wide variety of potential mutations that can lead to this result, and they are located on several different chromosomes. One notable case is of ocular albinisms, which only affect the eyes (and not the skin). These mutations have been shown to be present almost exclusively on the X chromosome. As a result, most individuals affected with X-linked ocular albinism will be male, similar to the genetics of X-linked color blindness.

365

Multiple nuclear loci reveal patterns of incomplete lineage sorting and complex species history within western mouse lemurs (Microcebus)  

E-Print Network (OSTI)

of karyotypic fission theory. Proc. Nat. Acad. Sci. 97: 9493­9497. KOUYOS, R.D., OTTO, S.P. & BONHOEFFER, S

Yoder, Anne

366

Characterization of microsatellite loci in Kearney's bluestar (Amsonia keameyana) and cross-amplification in other Amsonia species  

E-Print Network (OSTI)

Arizona) and Steve McLaughlin ( University of Arizona) forthe genus (Woodson 1928; McLaughlin 1982). Most of the knownPhytochemical Bulletin, 19, McLaughlin SP (1982) A Revision

Topinka, J. Rick; Donovan, A J; May, B

2004-01-01T23:59:59.000Z

367

Microarray analysis identifies keratin loci as sensitive biomarkers for thyroid hormone disruption in the salamander Ambystoma mexicanum  

E-Print Network (OSTI)

hit to the human genome. 22 R.B. Page et al. / Comparative Biochemistry and Physiology, Part C 145 to the human genome. Dark circles represent the mean of three samples±S.E. Fig. 5. Up-regulated keratins. The y based on the best BLASTX hit to the human genome. Dark circles represent the mean of three samples

368

Isolation and characterization of microsatellite loci in the rock scallop (Spondylus calcifer) (Bivalvia: Spondylidae) from the Northern Gulf California, Mexico  

E-Print Network (OSTI)

from the Northern Gulf California, Mexico A. Munguia-Vega •National Park, Gulf of California, Mexico. J Shell?sh Resin the northern Gulf of California, Mexico. Keywords Gulf of

Munguia-Vega, A.; Soria, G.; Pfister, T.; Cudney-Bueno, R.

2010-01-01T23:59:59.000Z

369

Microsatellite loci for the blue swimming crab (Callinectes bellicosus) (Crustacea: Portunidae) from the Gulf of California, Mexico  

E-Print Network (OSTI)

shery started in the Gulf of Mexico, and developed in thePortunidae) from the Gulf of California, Mexico A. Munguia-species from the Gulf of California, Mexico. One locus was

Munguia-Vega, A.; Torre, J.; Castillo-Lopez, A.; Pfister, T.; Cudney-Bueno, R.

2010-01-01T23:59:59.000Z

370

A Genome-Wide Association Study Suggests Novel Loci Associated with a Schizophrenia-Related Brain-Based Phenotype  

E-Print Network (OSTI)

Patients with schizophrenia and their siblings typically show subtle changes of brain structures, such as a reduction of hippocampal volume. Hippocampal volume is heritable, may explain a variety of cognitive symptoms of ...

Hass, Johanna

371

Final Report-DE FG02 92ER20061  

SciTech Connect

A dosage analysis of gene expression was conducted using aneuploids of maize. The findings of this project led to the concept that regulatory genes in higher eukaryotes has mostly dosage dependent and are the underlying basis of quantitative traits and aneuploid syndromes.

James A. Birchler

2004-04-22T23:59:59.000Z

372

Mood, food, traits, and restraint: an experimental investigation of negative affect, borderline personality, and disordered eating  

E-Print Network (OSTI)

Eating disorders and borderline personality disorder involve several overlapping features, such as impulsivity, negative affectivity, and dissociation. However, few studies have specifically assessed how eating pathology and borderline personality may be related. The present study sought to evaluate this relationship by focusing on one particular area of overlap, negative affectivity. A pilot study assessed the psychometric properties of a dietary restraint measure among undergraduate women (N = 149). In the main study, undergraduate women (N = 307) completed a baseline mood assessment, then viewed a 39-minute sad film either with or without concurrent food presentation. Participants then completed a second mood assessment, and those who received food completed a third mood assessment following a 10-minute post-reflection delay. Results suggest that women reporting more borderline features exhibited greater negative affect across three different time points (baseline, post-movie/food, and post-reflection period), and were more reactive to the sad film. Food presentation appeared to have a small tempering effect on sadness, such that individuals who received food reported relatively less sadness after viewing the film when compared to those who did not receive food. However, actual quantity of food consumption was associated with improvements in mood only for women reporting higher levels of borderline features. Finally, highscorers on dietary restraint measures consumed greater quantities of food than their lowscoring counterparts. In sum, these data suggest that women with borderline personality features may be at elevated risk for developing problems with binge-eating, as consuming larger quantities of food appeared to have a tempering effect on their negative mood and specific feelings of sadness. Further, results are consistent with earlier findings in that reported efforts to restrain dietary intake were associated with greater food consumption in response to negative affect, and this relationship may need to be addressed in treating individuals with problematic eating behaviors.

Ambwani, Suman

2008-08-01T23:59:59.000Z

373

Predicting Maximum Tree Heights and Other Traits from Allometric Scaling and Resource Limitations  

E-Print Network (OSTI)

Terrestrial vegetation plays a central role in regulating the carbon and water cycles, and adjusting planetary albedo. As such, a clear understanding and accurate characterization of vegetation dynamics is critical to ...

Kempes, Chris Poling

374

Male reproductive traits, semen cryopreservation, and heterologous in vitro fertilization in the bobcat (Lynx rufus)  

E-Print Network (OSTI)

). Figure 2 Procedure for the preparation of the test assembly set up inside the wind tunnel. #12 Transactions EXPERIMENTAL PROCEDURE AND UNCERTAINTY ANALYSIS All tests were conducted with the fin sample estimated through a series of in- situ calibration tests in our laboratory. The heat transfer rate

Museo Nacional de Ciencias Naturales

375

Population variation in the life history traits and thermal responses of Atlantic cod, Gadus morhua L.  

E-Print Network (OSTI)

??Studies of the phenotypes of animals at different parts of their geographic range often reveal striking variability. It is of considerable fundamental and applied interest… (more)

Perutz, Marion

2007-01-01T23:59:59.000Z

376

Some Language Traits in the Ladwags Version of the Gesar Epic  

E-Print Network (OSTI)

<. C<. .... ...,.,.... ...,.,.... ...,.,.... 1 -9Zll'Zll' -9ZllT~~' ~C;:'~' q~'~C;:' ~C;:'q'~~'~~Zll' all .... ", .... "'"' ...,.,.... c-...,.,.... ...,.,.... I t.l::t\\'''1~' t.l::t\\'F-J ~C;:'~' O-l'C;:~'~' ~C;:'~Zll' ~~'~~Zll'all "' .......,.,.... I...

Mukerjee, Bandana

1997-01-01T23:59:59.000Z

377

Latin America’s New World of Work: Changing Traits of Work and Problem Solving  

E-Print Network (OSTI)

the Impact of Choice in Venezuela. ” Manuscript. Hussmanns,Argentina; Caracas, Venezuela; Lima, Peru, and Santiago,place in Argentina and Venezuela around the time of the

Collier, Ruth Berins; Palmer-Rubin, Brian

2011-01-01T23:59:59.000Z

378

A Novel Gene Family Controls Species-Specific Morphological Traits in Hydra  

E-Print Network (OSTI)

Institute, Christian-Albrechts-University, Am Botanishen Garten 1-9, 24118 Kiel, Germany Understanding

Bosch, Thomas C. G.

379

Molecular and computational approaches to identification of genes underlying complex traits  

E-Print Network (OSTI)

Press; 2002. Paterson AH. Molecular Dissection of ComplexCALIFORNIA, SAN DIEGO Molecular and computational approachesof Doctor of Philosophy in Molecular Pathology by Martin L.

Jirout, Martin L.

2008-01-01T23:59:59.000Z

380

Effects of Trait Behavioral Approach and Inhibition Sensitivity on Behavioral Aggression  

E-Print Network (OSTI)

Behavioral approach sensitivity (BAS) has been found to relate to anger contrary to perspectives positing that BAS is only involved in positive emotions. The present study extends this work by examining relations between behavioral aggression and BAS and behavioral inhibition sensitivity (BIS) measures. Forty-three undergraduate participants were socially ostracized to induce anger, and then given an opportunity to behave aggressively. Higher levels of BAS relate to increased aggressive behavior, whereas higher levels of BIS related to decreased aggressive behavior.

Gravens, Laura Christine

2011-05-01T23:59:59.000Z

Note: This page contains sample records for the topic "quantitative trait loci" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


381

Characterization of grain sorghum for physiological and yield traits associated with drought tolerance.  

E-Print Network (OSTI)

??Grain sorghum (Sorghum bicolor L. Moench) is the fourth most important cereal crop grown throughout the semi-arid regions of the world. It is a staple… (more)

Mutava, Raymond N.

2009-01-01T23:59:59.000Z

382

Tamang jatibare sangkshipta sabda citra Traite sur l'origine de la caste tamang  

E-Print Network (OSTI)

de vie dans le monde, le Tamba dit shar lho nub byang phyogs mchams ri’ ’gro ba rigs drug mi chags cim ”En direction de l’Est, du Sud, de l’Ouest, du Nord” ”Six sortes d’êtres vivants ont été créés” ( mngal skyes: tous les animaux nés de la... ;may#7;na, le Singe qui incarnait la force, Hanum#7;n, serait arrivé chez Avalokite vara, sur la colline du Potala. Avalokite vara envoya le singe méditer dans l’Himalaya. Pour la théologie du Bon, Avalokite vara est incarné dans Gçen rab mi...

Lama, Thubten

2007-01-01T23:59:59.000Z

383

Combinational pixel-by-pixel and object-level classifying, segmenting, and agglomerating in performing quantitative image analysis that distinguishes between healthy non-cancerous and cancerous cell nuclei and delineates nuclear, cytoplasm, and stromal material objects from stained biological tissue materials  

DOE Patents (OSTI)

Quantitative object and spatial arrangement-level analysis of tissue are detailed using expert (pathologist) input to guide the classification process. A two-step method is disclosed for imaging tissue, by classifying one or more biological materials, e.g. nuclei, cytoplasm, and stroma, in the tissue into one or more identified classes on a pixel-by-pixel basis, and segmenting the identified classes to agglomerate one or more sets of identified pixels into segmented regions. Typically, the one or more biological materials comprises nuclear material, cytoplasm material, and stromal material. The method further allows a user to markup the image subsequent to the classification to re-classify said materials. The markup is performed via a graphic user interface to edit designated regions in the image.

Boucheron, Laura E

2013-07-16T23:59:59.000Z

384

Gender determination in populus  

DOE Green Energy (OSTI)

Gender, the expression of maleness or femaleness, in dioecious plants has been associated with changes in morphology, physiology, ecological position, and commercial importance of several species, including members of the Salicaceae family. Various mechanisms have been proposed to explain the expression of gender in Salicaceae, including sex chromosomes, simple Mendelian genes, quantitative genes, environment, and genotype-by-environment interactions. Published reports would favor a genetic basis for gender. The objective of this study was to identify molecular markers associated with gender in a segregating family of hybrid poplars. Bulked segregant analysis and chi-squared analysis were used to test for the occurrence of sex chromosomes, individual loci, and chromosome ratios (i.e., ploidy levels) as the mechanisms for gender determination. Examination of 2488 PCR based RAPD markers from 1219 primers revealed nine polymorphic bands between male and female bulked samples. However, linkage analysis indicated that none of these markers were significantly associated with gender. Chisquared results for difference in male-to-female ratios between diploid and triploid genotypes also revealed no significant differences. These findings suggest gender is not controlled via sex chromosomes, simple Mendelian loci or ratios of autosome to gender-determining loci. It is possible that gender is determined genetically by regions of the genome not sampled by the tested markers or by a complex of loci operating in an additive threshold manner or in an epistatic manner. It is also possible that gender is determined environmentally at an early zygote stage, canalizing gender expression.

McLetchie, D.N. [Univ. of Kentucky, Lexington, KY (United States). Dept. of Biological Sciences; Tuskan, G.A. [Oak Ridge National Lab., TN (United States)

1994-12-31T23:59:59.000Z

385

Quantitative Assessment of Islets of Langerhans Encapsulated in Alginate  

E-Print Network (OSTI)

Improved methods have recently been developed for assessing islet viability and quantity in human islet

Johnson, Amy S.

386

Quantitative study of rectangular waveguide behavior in the THz.  

SciTech Connect

This report describes our efforts to quantify the behavior of micro-fabricated THz rectangular waveguides on a configurable, robust semiconductor-based platform. These waveguides are an enabling technology for coupling THz radiation directly from or to lasers, mixers, detectors, antennas, and other devices. Traditional waveguides fabricated on semiconductor platforms such as dielectric guides in the infrared or co-planar waveguides in the microwave regions, suffer high absorption and radiative losses in the THz. The former leads to very short propagation lengths, while the latter will lead to unwanted radiation modes and/or crosstalk in integrated devices. This project exploited the initial developments of THz micro-machined rectangular waveguides developed under the THz Grand Challenge Program, but instead of focusing on THz transceiver integration, this project focused on exploring the propagation loss and far-field radiation patterns of the waveguides. During the 9 month duration of this project we were able to reproduce the waveguide loss per unit of length in the waveguides and started to explore how the loss depended on wavelength. We also explored the far-field beam patterns emitted by H-plane horn antennas attached to the waveguides. In the process we learned that the method of measuring the beam patterns has a significant impact on what is actually measured, and this may have an effect on most of the beam patterns of THz that have been reported to date. The beam pattern measurements improved significantly throughout the project, but more refinements of the measurement are required before a definitive determination of the beam-pattern can be made.

Rowen, Adam M.; Nordquist, Christopher Daniel; Wanke, Michael Clement

2009-10-01T23:59:59.000Z

387

Real Time Quantitative Radiological Monitoring Equipment for Environmental Assessment  

SciTech Connect

The Idaho National Laboratory (INL) has developed a suite of systems that rapidly scan, analyze, and characterize radiological contamination in soil. These systems have been successfully deployed at several Department of Energy (DOE) laboratories and Cold War Legacy closure sites. Traditionally, these systems have been used during the characterization and remediation of radiologically contaminated soils and surfaces; however, subsequent to the terrorist attacks of September 11, 2001, the applications of these systems have expanded to include homeland security operations for first response, continuing assessment and verification of cleanup activities in the event of the detonation of a radiological dispersal device. The core system components are a detector, a spectral analyzer, and a global positioning system (GPS). The system is computer controlled by menu-driven, user-friendly custom software designed for a technician-level operator. A wide variety of detectors have been used including several configurations of sodium iodide (NaI) and high-purity germanium (HPGe) detectors, and a large area proportional counter designed for the detection of x-rays from actinides such as Am-241 and Pu-238. Systems have been deployed from several platforms including a small all-terrain vehicle (ATV), hand-pushed carts, a backpack mounted unit, and an excavator mounted unit used where personnel safety considerations are paramount. The INL has advanced this concept, and expanded the system functionality to create an integrated, field-deployed analytical system through the use of tailored analysis and operations software. Customized, site specific software is assembled from a supporting toolbox of algorithms that streamline the data acquisition, analysis and reporting process. These algorithms include region specific spectral stripping, automated energy calibration, background subtraction, activity calculations based on measured detector efficiencies, and on-line data quality checks and measures. These analyses are combined to provide real-time areal activity and coverage maps that are displayed to the operator as the survey progresses. The flexible functionality of the INL systems are well suited to multiple roles supporting homeland security needs.

John R. Giles; Lyle G. Roybal; Michael V. Carpenter

2006-03-01T23:59:59.000Z

388

Quantitative Financial Analysis of Alternative Energy Efficiency Shareholder Incentive Mechanisms  

E-Print Network (OSTI)

reduce total energy and energy service costs for customerscost of electricity and energy services for consumers andof energy efficiency programs in a given state or service

Cappers, Peter

2010-01-01T23:59:59.000Z

389

Journal of Quantitative Spectroscopy & Radiative Transfer 109 (2008) 13351337  

E-Print Network (OSTI)

, Antalya in 2001 [10], and Istanbul in 2004 [11]. RAD-V was organized by M. Pinar Mengu¨ c- and Nevin Selc, Adelphi, MD, USA M. Pinar Mengu¨ c-, University of Kentucky, Lexington, KY, USA Organizing committee Jay, Astronomical Institute ``Anton Pannekoek'', University of Amsterdam, The Netherlands Hal Maring, NASA HQ

390

A quantitative study of a physics-first pilot program  

SciTech Connect

Hundreds of high schools around the United States have inverted the traditional core sequence of high school science courses, putting physics first, followed by chemistry, and then biology. A quarter-century of theory, opinion, and anecdote are available, but the literature lacks empirical evidence of the effects of the program. The current study was designed to investigate the effects of the program on science achievement gain, growth in attitude toward science, and growth in understanding of the nature of scientific knowledge. One hundred eighty-five honor students participated in this quasi-experiment, self-selecting into either the traditional or inverted sequence. Students took the Explore test as freshmen, and the Plan test as sophomores. Gain scores were calculated for the composite scores and for the science and mathematics subscale scores. A two-factor analysis of variance (ANOVA) on course sequence and cohort showed significantly greater composite score gains by students taking the inverted sequence. Participants were administered surveys measuring attitude toward science and understanding of the nature of scientific knowledge twice per year. A multilevel growth model, compared across program groups, did not show any significant effect of the inverted sequence on either attitude or understanding of the nature of scientific knowledge. The sole significant parameter showed a decline in student attitude independent of course sequence toward science over the first two years of high school. The results of this study support the theory that moving physics to the front of the science sequence can improve achievement. The importance of the composite gain score on tests vertically aligned with the high-stakes ACT is discussed, and several ideas for extensions of the current study are offered.

Pasero, Spencer Lee; /Northern Illinois U.

2008-09-01T23:59:59.000Z

391

Graphical interface for quantitative monitoring of 3D MRI data  

E-Print Network (OSTI)

The recent development of techniques in magnetic resonance imaging allows for the noninvasive monitoring of cartilage for disease progression, effects of lifestyle change, and results of medical interventions. In particular, ...

Gerber, Meredith L

2005-01-01T23:59:59.000Z

392

Quantitative analysis of the receptor-induced apoptotic decision network  

E-Print Network (OSTI)

Cells use a complex web of protein signaling pathways to interpret extracellular cues and decide and execute cell fates such as survival, apoptosis, differentiation, and proliferation. Cell decisions can be triggered by ...

Aldridge, Bree Beardsley

2008-01-01T23:59:59.000Z

393

Quantitative Carbon Partitioning Diagrams for Waspaloy and Their ...  

Science Conference Proceedings (OSTI)

of carbon between MC, Mg3C6 and solid solu- tion was measured for Waspaloy in support of homogenization, chemistry modification, and thermomechanical.

394

Quantitative analysis of inclusion distributions in hot pressed silicon carbide  

SciTech Connect

ABSTRACT Depth of penetration measurements in hot pressed SiC have exhibited significant variability that may be influenced by microstructural defects. To obtain a better understanding regarding the role of microstructural defects under highly dynamic conditions; fragments of hot pressed SiC plates subjected to impact tests were examined. Two types of inclusion defects were identified, carbonaceous and an aluminum-iron-oxide phase. A disproportionate number of large inclusions were found on the rubble, indicating that the inclusion defects were a part of the fragmentation process. Distribution functions were plotted to compare the inclusion populations. Fragments from the superior performing sample had an inclusion population consisting of more numerous but smaller inclusions. One possible explanation for this result is that the superior sample withstood a greater stress before failure, causing a greater number of smaller inclusions to participate in fragmentation than in the weaker sample.

Michael Paul Bakas

2012-12-01T23:59:59.000Z

395

Quantitative measures of MIS quality assurance during hardware conversion  

Science Conference Proceedings (OSTI)

The management information systems (MIS) department of Medtronic converted their applications from running on the computer of one hardware vendor to another. A quality assurance (QA) program was instituted to monitor, validate, and assist in the conversion ...

John W. Center

1981-05-01T23:59:59.000Z

396

Systematic quantitative characterization of cellular responses induced by multiple signals  

E-Print Network (OSTI)

Ram PT: Identification of Optimal Drug Combinations Targeting Cellular Networks: Integrating Phospho- Proteomics and Computational Network Analysis.

2011-01-01T23:59:59.000Z

397

Quantitative Study of Stoichiometric Proton Imbalance in Phototrophic Algal Growth.  

E-Print Network (OSTI)

??The high production of algae based biofuel requires high density of algae culture. One of the important issues associated with high density algae cultivation is… (more)

Wang, Jun

2013-01-01T23:59:59.000Z

398

A New Approach to Quantitative NIF GXD Image Analysis  

E-Print Network (OSTI)

Bull. Am. Phys. Soc. 55, 117 (2010)52nd American Physical Society Annual Meeting of Division of Plasma Physics Chicago Illinois, US, 2010999618315

Huang, H.

2010-08-17T23:59:59.000Z

399

N6: Quantitative Characterization of Lath Martensite in Japanese ...  

Science Conference Proceedings (OSTI)

N11: Microbilogically Influenced Corrosion of Pipeline Steels used in Oil & Gas Industry ... N2: Fabrication of Uranium Dispersion Targets for Mo-99 Production ... Numerical Modelling for Characterising the Flammability of Natural Fibre ...

400

Field Evidence Supporting Quantitative Predictions of Secondary Ice Production Rates  

Science Conference Proceedings (OSTI)

Field observations from three different areas in the United States are used to determine the rates of appearance of ice particles in cumulus clouds. Those rates are compared to predictions obtained using the laboratory studies of the Hallett-...

Raymond L. Harris-Hobbs; William A. Cooper

1987-04-01T23:59:59.000Z

Note: This page contains sample records for the topic "quantitative trait loci" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


401

Quantitative motor function evaluation: the VAMA project experience  

Science Conference Proceedings (OSTI)

This paper aims at reviewing the experience maturated over the past decade by this group in the framework of the VAMA (Italian acronym for “evaluation of motor ability in the elderly”) project. The objective of that research programme was ... Keywords: Biomechanics, Data Mining, Motor Ability Assessment, Movement Analysis, Musculoskeletal Modelling

Aurelio Cappozzo; Valentina Camomilla; Ugo Della Croce; Claudia Mazzà; Giuseppe Vannozzi

2009-07-01T23:59:59.000Z

402

Fundamental quantitative analysis of microbial activity in aquifer bioreclamation  

SciTech Connect

In situ bioremediation of hazardous organic chemicals that contaminate aquifer solids and ground water is a highly promising technique for many sites at DOE facilities. Its potential stems from having agents for destruction of the contaminants (bacteria) close to the separate-phase liquid or sorbed contaminants. This project was designed to advance knowledge in several of the microbiological fundamentals most important to in situ bioremediation: biodegradation of poorly soluable organic contaminants; dual limitation kinetics of electron donors and acceptors; kinetics of sequential degradation involving oxygenase reaction; biologically induced clogging in porous media, and two dimensional modeling of biofilm reactions in non homogeneous porous media.

Rittman, B.E.; Valocchi, A.J. [Univ. of Illinois, Urbana, IL (United States). Dept. of Civil Engineering; Baveye, P. [Cornell Univ., Ithaca, NY (United States). Dept. of Agronomy

1993-08-01T23:59:59.000Z

403

Quantitative Financial Analysis of Alternative Energy Efficiency Shareholder Incentive Mechanisms  

E-Print Network (OSTI)

assumptions for the utility’s growth rates, cost structure,Southwest utility with high growth rates and low cost energyprototypical utility produces an all-in average retail rate

Cappers, Peter

2010-01-01T23:59:59.000Z

404

Quantitative relationship of sick building syndrome symptoms with ventilation rates  

E-Print Network (OSTI)

32%), and as ventilation rate increases from 10 to 25 L/s-0.85) as ventilation rate increases from 10 to 25 L/s-29% as ventilation rate increases from 10 to 25 L/s-person.

Fisk, William J.

2009-01-01T23:59:59.000Z

405

A Quantitative Understanding of Interface Dynamics in Complex ...  

Science Conference Proceedings (OSTI)

... of applications, ranging from solid oxide fuel cells to magneto-electric devices. ... Active Titania-Based Nanoparticles for Composite Propellant Combustion.

406

Quantitative Ice Accretion Information from the Automated Surface Observing System  

Science Conference Proceedings (OSTI)

Freezing precipitation is a persistent winter weather problem that costs the United States millions of dollars annually. Costs and infrastructure disruption may be greatly reduced by ice-storm warnings issued by the National Weather Service (NWS),...

Charles C. Ryerson; Allan C. Ramsay

2007-09-01T23:59:59.000Z

407

Towards Quantitative Simulations of High Power Proton Cyclotrons  

E-Print Network (OSTI)

PSI operates a cyclotron based high intensity proton accelerator routinely at an average beam power of 1.3MW. With this power the facility is at the worldwide forefront of high intensity proton accelerators. The beam current is practically limited by losses at extraction and the resulting activation of accelerator components. Further intensity upgrades and new projects aiming at an even higher average beam power, are only possible if the relative losses can be lowered in proportion, thus keeping absolute losses at a constant level. Maintaining beam losses at levels allowing hands-on maintenance is a primary challenge in any high power proton machine design and operation. In consequence, predicting beam halo at these levels is a great challenge and will be addressed in this paper. High power hadron driver have being used in many disciplines of science and, a growing interest in the cyclotron technology for high power hadron drivers are being observed very recently. This report will briefly introduce OPAL, a tool for precise beam dynamics simulations including 3D space charge. One of OPAL's flavors (OPAL-cycl) is dedicated to high power cyclotron modeling and is explained in greater detail. We then explain how to obtain initial conditions for our PSI Ring cyclotron which still delivers the world record in beam power of 1.3 MW continuous wave (cw). Several crucial steps are explained necessary to be able to predict tails at the level of 3\\sigma ... 4\\sigma in the PSI Ring cyclotron. We compare our results at the extraction with measurements, obtained with a 1.18 MW cw production beam. Based on measurement data, we develop a simple linear model to predict beam sizes of the extracted beam as a function of intensities and confirm the model with simulations.

Y. J. Bi; A. Adelmann; R. Dölling; M. Humbel; W. Joho; M. Seidel; T. J. Zhang

2010-12-03T23:59:59.000Z

408

A quantitative design and analysis of magnetic nanoparticle heating systems  

E-Print Network (OSTI)

Magnetic particles under the influence of an alternating magnetic field act as localized heating sources due to various loss mechanisms. This effect has been extensively investigated in hypothermia studies over the past ...

Khushrushahi, Shahriar Rohinton

2006-01-01T23:59:59.000Z

409

Journal of Quantitative Spectroscopy & Radiative Transfer 73 (2002) 583602  

E-Print Network (OSTI)

Engenharia Mec^anica, Universidade Federal do Rio Grande do Sul, 90050-170 Porto Alegre, RS, Brazil c

Siewert, Charles E.

410

Quantitative Financial Analysis of Alternative Energy Efficiency Shareholder Incentive Mechanisms  

E-Print Network (OSTI)

References Consortium for Energy Efficiency (CEE) 2008.Energy Efficiency Programs: 2007 Report”Action Plan for Energy Efficiency, 2007. “Aligning Utility

Cappers, Peter

2010-01-01T23:59:59.000Z

411

Quantitative Analysis of Alternative Transportation Under Environmental Constraints  

E-Print Network (OSTI)

Mazda Bongo Shunt dc motor Conceptor G-Van Separately excited dc motor Suzuki Senior Tricycle PM dc/kWh) VRLA 30-40 60-90 200-300 400-600 150 Ni-Cd 40-60 80-110 150-350 600-1200 300 Ni-Zn 60-65 120-130 150 to separate oxygen molecules. Platinum is currently used, just as it is used to break hydrogen molecules

412

Quantitative imaging of living cells by deep ultraviolet microscopy  

E-Print Network (OSTI)

Developments in light microscopy over the past three centuries have opened new windows into cell structure and function, yet many questions remain unanswered by current imaging approaches. Deep ultraviolet microscopy ...

Zeskind, Benjamin J

2006-01-01T23:59:59.000Z

413

Fluorescence laser tracking microrheology for quantitative studies of cytoskeletal mechanotransduction  

E-Print Network (OSTI)

To shed light on the cell's response to its mechanical environment, we examined cell rheology at the single cell level and quantified it with nanometer spatial and microsecond temporal resolutions over a five-decade frequency ...

Jonas, Maxine

2007-01-01T23:59:59.000Z

414

Quantitative Financial Analysis of Alternative Energy Efficiency Shareholder Incentive Mechanisms  

E-Print Network (OSTI)

Analysis of Alternative Energy Efficiency ShareholderAnalysis of Alternative Energy Efficiency Shareholderof alternative shareholder incentive mechanisms for energy

Cappers, Peter

2010-01-01T23:59:59.000Z

415

Real-time quantitative imaging of failure events in materials ...  

reflector aimed at the centre of the cell (Fig.1b), giving a spherical hot zone of diameter ?5mm. Temperatures of test samples in the

416

Probabilistic Quantitative Precipitation Forecasting Using Bayesian Model Averaging  

Science Conference Proceedings (OSTI)

Bayesian model averaging (BMA) is a statistical way of postprocessing forecast ensembles to create predictive probability density functions (PDFs) for weather quantities. It represents the predictive PDF as a weighted average of PDFs centered on ...

J. Mc Lean Sloughter; Adrian E. Raftery; Tilmann Gneiting; Chris Fraley

2007-09-01T23:59:59.000Z

417

Verifying Quantitative Reliability of Programs That Execute on Unreliable Hardware  

E-Print Network (OSTI)

Emerging high-performance architectures are anticipated to contain unreliable components that may exhibit soft errors, which silently corrupt the results of computations. Full detection and recovery from soft errors is ...

Carbin, Michael

2013-06-19T23:59:59.000Z

418

A Geometallurgical Approach of REE Deposits Using Quantitative ...  

Science Conference Proceedings (OSTI)

Characterization of Indonesia Rare Earth Minerals and their Potential Processing Techniques · Characterization of Rare Earth Minerals with Field Emission ...

419

Quantitative Estimates of the Effect of Lake Michigan on Snowfall  

Science Conference Proceedings (OSTI)

A climatological study of snowfall in the snowbelts of Michigan shows that decade-average amounts varied by a factor of 2 during the period from 1909/10 through 1980/81.

Roscoe R. Braham Jr.; Maureen J. Dungey

1984-06-01T23:59:59.000Z

420

A new and improved quantitative recovery analysis for iterative hard ...  

E-Print Network (OSTI)

Sep 20, 2013 ... †Department of Mathematics, Duke University, Box 90320, Durham, NC ...... is derived which multiplies the unrecoverable energy of the signal, ...

Note: This page contains sample records for the topic "quantitative trait loci" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


421

Quantitative Financial Analysis of Alternative Energy Efficiency Shareholder Incentive Mechanisms  

E-Print Network (OSTI)

recent introduction of Duke Energy’s Save-a-Watt incentiverecent introduction of Duke Energy’s Save-a-Watt shareholdermechanism proposed by Duke Energy). 13 Program costs are not

Cappers, Peter

2010-01-01T23:59:59.000Z

422

Quantitative characterization of multi-variable human ankle mechanical impedance  

E-Print Network (OSTI)

Ankle mechanical impedance, which is a dynamic relationship between angular displacement and the corresponding torque at the ankle joint, plays a key role in natural interaction of the lower-extremity with the environment. ...

Lee, Hyunglae

2013-01-01T23:59:59.000Z

423

Accuracy in quantitative phase analysis of complex mineral ...  

Science Conference Proceedings (OSTI)

... Soil formed on a parent material rich in ferromagnesian minerals and amorphous soil minerals • Petroleum shale • Nickel laterite • Bauxite ...

2013-06-07T23:59:59.000Z

424

X-Ray Phase-Contrast Tomography for Quantitative ...  

Science Conference Proceedings (OSTI)

... in a range of areas including analysis of self-healing polymers, visualisation of fluids in porous materials, .... Tool Failure Criteria while Drilling Titanium Alloys.

425

A Quantitative Assessment of the NESDIS Auto-Estimator  

Science Conference Proceedings (OSTI)

A systematic evaluation of the National Environmental Satellite, Data and Information Service Auto-Estimator (A-E), a satellite-based algorithm for the estimation of rainfall, was performed for a 13-month period ending December 1998. This effort ...

Robert A. Rozumalski

2000-08-01T23:59:59.000Z

426

Opposites attract: computational and quantitative outreach through artistic expressions  

Science Conference Proceedings (OSTI)

Staff from the University of Tennessee's Joint institute for Computational Sciences, National Institute for Computational Sciences, and Remote Data Analysis and Visualization Center have teamed up with faculty from UT's School of Art to engage with students, ... Keywords: art, computational science, data science, education, media arts, new media, outreach, participatory art, video, visualization

Amy F. Szczepa?ski; Christal Yost; Norman Magden; Evan Meaney; Carolyn I. Staples

2013-07-01T23:59:59.000Z

427

10 Questions for a Quantitative Geneticist: Wellington Muchero...  

NLE Websites -- All DOE Office Websites (Extended Search)

revolved around us. Q: What is 'cell wall recalcitrance' and why does it matter for biofuels production? WM: Cellulose is one of the most abundant polymers on earth -- most of...

428

The NIST 3 Megawatt Quantitative Heat Release Rate Facility  

Science Conference Proceedings (OSTI)

... A pair of disposable flat disk filters is used to ... is a constant if the speeds of the roof and control ... generated pulse shapes such as a flatter top section ...

2004-07-14T23:59:59.000Z

429

A Quantitative Study of Robustness Characteristics in Steel Framed Structures.  

E-Print Network (OSTI)

??Robustness is a desirable property in any structural design. Robustness may be thought of as the building's inherent structural ability to resist loads other than… (more)

Raebel, Christopher Herman

2011-01-01T23:59:59.000Z

430

Quantitative Financial Analysis of Alternative Energy Efficiency Shareholder Incentive Mechanisms  

E-Print Network (OSTI)

rates and low cost energy efficiency. The quantitativeavailable cost-effective energy efficiency, and some statesachievable cost-effective energy efficiency. At the same

Cappers, Peter

2010-01-01T23:59:59.000Z

431

Symbolic and Quantitative Approaches to Reasoning with ... - Springer  

Science Conference Proceedings (OSTI)

Alert Systems for Production Plants: A Methodology Based on Conflict Analysis · Thomas D. Nielsen,; Finn V. Jensen … show all 2 hide. Download PDF (343KB).

432

Quantitative cerebral blood flow with optical coherence tomography  

E-Print Network (OSTI)

Absolute measurements of cerebral blood flow (CBF) are an important endpoint in studies of cerebral pathophysiology. Currently no accepted method exists for in vivo longitudinal monitoring of CBF with high resolution in ...

Srinivasan, Vivek J.

433

ASHRAE Standard 90.1-2004 Quantitative Analysis Worksheet | Building...  

NLE Websites -- All DOE Office Websites (Extended Search)

used in support of the U.S. Department of Energy's determination regarding whether ASHRAE Standard 90.1-2004 will improve energy efficiency in commercial buildings. This...

434

Optogalvanic intracavity quantitative detector and method for its use  

SciTech Connect

The disclosure relates to an optogalvanic intracavity detector and method for its use. Measurement is made of the amount of light absorbed by atoms, small molecules and ions in a laser cavity utilizing laser-produced changes in plasmas containing the same atoms, molecules, or ions.

Zalewski, Edward F. (Gaithersburg, MD); Keller, Richard A. (Los Alamos, NM); Apel, Charles T. (Los Alamos, NM)

1983-01-01T23:59:59.000Z

435

Quantitative determination of the absorption spectraof chromophores in strongly scattering  

E-Print Network (OSTI)

: a light-emitting-diode based technique Sergio Fantini, Maria and Enrico Gratton Angela Franceschini in the spectral range from 620 to 700 nm. We conduct the measurements in the frequency domain by using a light-emitting diode(LED) whose intensity is modulated at a frequency of 60 MHz. We derive an analytical expression

Fantini, Sergio

436

Quantitative Analysis of Vascular Structures Using Image Processing  

Science Conference Proceedings (OSTI)

Vascularization, the growth of new blood vessels form the existing vessels, implies many pathological processes and needs to be reasonably quantified. However, most vascular analysis is done manually. This is a tedious and laborious work without consistence. ... Keywords: vascularization, angiostatic analysis, image processing

Yi-Chun Lin; Pei-Ju Chiang

2012-07-01T23:59:59.000Z

437

Quantitative Financial Analysis of Alternative Energy Efficiency Shareholder Incentive Mechanisms  

E-Print Network (OSTI)

in customers, energy sales, peak demand, and non-fuel O&Mof future sales, peak demand, and its resource strategy toyear elect sales, peak demand, emission levels, financials,

Cappers, Peter

2010-01-01T23:59:59.000Z

438

Quantitative Analysis of Three-dimensional Grain Growth  

Science Conference Proceedings (OSTI)

P2-03: 3D Characterization of High Burn-up MOX Fuel · P2-04: 3D Identification of Inclusions in NiTi Alloy after Electropolishing · P2-05: Advances in 3D Imaging  ...

439

Quantitative Evaluation of the Cracking of Carbon Anodes by Image ...  

Science Conference Proceedings (OSTI)

Nanothermites: Unconventional Nanomaterials with High Energy Output · Nitriding Surface Treatments to Improve Water Droplet Erosion Resistance.

440

D6: Quantitative Analysis of Dynamic Recrystallization in Warm ...  

Science Conference Proceedings (OSTI)

D8: Study of Rack and Chord Assembly Formability for Jack-up Platforms ... Zone of Zr-Ti Microalloyed High-strength High-toughness Offshore Structural Steels.

Note: This page contains sample records for the topic "quantitative trait loci" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


441

Smart EFTEM-SI: A New Acquisition Procedure for Quantitative ...  

Science Conference Proceedings (OSTI)

Abstract Scope, Energy-filtering transmission electron microscopy (EFTEM) in ... A Hollow-Cone Dark Field (HCDF) Transmission Electron Microscopy (TEM) ...

442

Quantitation of products from riboflavin in rat urine  

SciTech Connect

When (2-/sup 14/C) riboflavin is injected i.p. into rats, the excreted vitamin in urine and feces has been shown to be the intact vitamin with trace amounts of lumichrome and lumiflavin. Recent findings with /sup 14/C-riboflavin fed to rats indicated higher levels of riboflavin catabolites in urine, e.g., 7- and 8-carboxylumichromes. The authors have determined catabolites in urine from male rats fed 0, 2, and 6 ..mu..g riboflavin/g diet/day for six weeks. Two rats from each group were placed weekly in metabolic cages, and urine was collected for 24 hours. On the fourth week, a third animal from each group received an i.p. injection of /sup 14/C-riboflavin and the urine was collected for 48 hours. Urine samples were extracted with phenol for flavin components and with chloroform for derivatives of lumichrome and lumiflavin. Riboflavin was the predominant flavin excreted by all diet groups with trace amounts of coenzymes and 7- and 8-hydroxymethylriboflavin. Riboflavin accounted for 85% of all the radioactivity recovered from the deficient and sufficient rats and 90% in rats fed excess. Lumichrome-type compounds including carboxylumichromes accounted for only a few % of recovered radioactivity. Thus, these components are primarily a product of intestinal microfloral degradation rather than significant tissue catabolites of riboflavin.

Chastain, J.L.; McCormick, D.B.

1986-03-05T23:59:59.000Z

443

Quantitative assessment of heteroplasmy levels in Senecio vulgaris ...  

Science Conference Proceedings (OSTI)

heteroplasmic cells, and comparison to nuclear genes. ... heteroplasmy or nuclear integration? ... Yan, H., W. Yuan, V.E. Velculescu, B. Vogelstein & K.W..

444

Quantitative and qualitative measures of decomposition: Is there a link?  

Science Conference Proceedings (OSTI)

Decomposition rates of loblolly pine coarse woody debris (CWD) were determined by mass loss and wood density changes for trees that differed in source of mortality (natural, girdle-poison, and felling). Specifically, three treatments were examined: (1) control (CON): natural mortality; (2) CD: 5-fold increase in CWD compared with the CON; and (3) CS: 12-fold increase in snags compared with the CON. The additional CWD in the CD treatment plots and the additional snags in the CS plots were achieved by felling (for the CD plots) or girdling followed by herbicide injection (for the CS plots) select trees in these plots. Consequently,mortality on the CD plots is due to natural causes and felling. Likewise, mortality on the CS plots is due to natural causes and girdle-poison. In each treatment plot, mortality due to natural causes was inventoried since 1997, whereas mortality due to girdle-poison and felling were inventoried since 2001. No significant difference was detected between the rates of decomposition for the CWD on these treatment plots, indicating that source of the tree mortality did not influence rates of decomposition once the tree fell. These experimental measures of decomposition were compared with two decay classification systems (three- and five-unit classifications) to determine linkages. Changes in wood density did not correlate to any decay classification, whereas mass loss had a weak correlation with decay class. However, the large degree of variation limits the utility of decay classification systems in estimating mass loss.

Eaton, Robert, J.; Sanchez, Felipe, G.

2009-03-01T23:59:59.000Z

445

In-situ Atomic Resolution Environmental TEM as Quantitative ...  

Science Conference Proceedings (OSTI)

Therefore, atomic-scale visualizing method by ETEM combined with the .... What Can We Learn from Measurements of Li-ion Battery Single Particles?

446

Quantitative analysis of alternative transportation under environmental constraints  

E-Print Network (OSTI)

This thesis focuses on the transportation sector and its role in emissions of carbon dioxide (CO2) and conventional pollutant emissions. Specifically, it analyzes the potential for hydrogen based transportation, introducing ...

Sandoval López, Reynaldo

2006-01-01T23:59:59.000Z

447

Quantitative Measurements of CME-driven Shocks from LASCO Observations  

E-Print Network (OSTI)

In this paper, we demonstrate that CME-driven shocks can be detected in white light coronagraph images and in which properties such as the density compression ratio and shock direction can be measured. Also, their propagation direction can be deduced via simple modeling. We focused on CMEs during the ascending phase of solar cycle 23 when the large-scale morphology of the corona was simple. We selected events which were good candidates to drive a shock due to their high speeds (V>1500 km/s). The final list includes 15 CMEs. For each event, we calibrated the LASCO data, constructed excess mass images and searched for indications of faint and relatively sharp fronts ahead of the bright CME front. We found such signatures in 86% (13/15) of the events and measured the upstream/downstream densities to estimate the shock strength. Our values are in agreement with theoretical expectations and show good correlations with the CME kinetic energy and momentum. Finally, we used a simple forward modeling technique to estimate the 3D shape and orientation of the white light shock features. We found excellent agreement with the observed density profiles and the locations of the CME source regions. Our results strongly suggest that the observed brightness enhancements result from density enhancements due to a bow-shock structure driven by the CME.

Veronica Ontiveros; Angelos Vourlidas

2008-11-24T23:59:59.000Z

448

Quantitative Financial Analysis of Alternative Energy Efficiency Shareholder Incentive Mechanisms  

E-Print Network (OSTI)

states have taken up the challenge of obtaining more energy efficiency, regulators are likely considering, if not already using, some type of incentivestate regulators. It is enlightening to assess the financial impact of the energy efficiency portfolio and the incentive

Cappers, Peter

2010-01-01T23:59:59.000Z

449

P3-21: Quantitative Analysis and Comparison of ?' Precipitate ...  

Science Conference Proceedings (OSTI)

P1-04: 3D Microstructural Characterization of Uranium Oxide as a Surrogate Nuclear ... P1-15: Gating System Optimisation Design Study of a Cast Automobile ... P2-27: Characterization of Carbonate Rocks through X-ray Microtomography.

450

Quantitative relationship of sick building syndrome symptoms with ventilation rates  

E-Print Network (OSTI)

at two outdoor air supply rates." Indoor Air 14 Suppl 8: 7-Miettinen (1995). "Ventilation rate in office buildings andAssociation of ventilation rates and CO 2 concentrations

Fisk, William J.

2009-01-01T23:59:59.000Z

451

Quantitative Characterization of Fly Ash Reactivity and Geopolymer ...  

Science Conference Proceedings (OSTI)

Typically, a combination of various cementitious products and radioactive caustic salts ... for future design of geopolymer mixtures for radioactive waste containment. ... Behavior and Properties of Fission Products and Actinides in High-Burnup ...

452

Optogalvanic intracavity quantitative detector and method for its use  

DOE Patents (OSTI)

The disclosure relates to an optogalvanic intracavity detector and method for its use. Measurement is made of the amount of light absorbed by atoms, small molecules and ions in a laser cavity utilizing laser-produced changes in plasmas containing the same atoms, molecules or ions.

Zalewski, E.F.; Keller, R.A.; Apel, C.T.

1981-02-25T23:59:59.000Z

453

Clinical feasibility of Raman spectroscopy for quantitative blood glucose measurement  

E-Print Network (OSTI)

Diabetes mellitus is a leading cause of morbidity and mortality worldwide, and close monitoring of blood glucose levels is crucial for its diagnosis and management. Currently, blood glucose monitoring is done by blood ...

Kong, Chae-Ryon

2011-01-01T23:59:59.000Z

454

B25: Direct Quantitative Elemental Analysis of High Purity Aluminum ...  

Science Conference Proceedings (OSTI)

C19: Dissolution Behavior of Cu Under Bump Metallization in Ball Grid Array Structure .... H2: Triboluminescent Smart Sensors for Structural Health Monitoring

455

Quantitative Analysis of Spectral Impacts on Silicon Photodiode Radiometers: Preprint  

DOE Green Energy (OSTI)

Inexpensive broadband pyranometers with silicon photodiode detectors have a non-uniform spectral response over the spectral range of 300-1100 nm. The response region includes only about 70% to 75% of the total energy in the terrestrial solar spectral distribution from 300 nm to 4000 nm. The solar spectrum constantly changes with solar position and atmospheric conditions. Relative spectral distributions of diffuse hemispherical irradiance sky radiation and total global hemispherical irradiance are drastically different. This analysis convolves a typical photodiode response with SMARTS 2.9.5 spectral model spectra for different sites and atmospheric conditions. Differences in solar component spectra lead to differences on the order of 2% in global hemispherical and 5% or more in diffuse hemispherical irradiances from silicon radiometers. The result is that errors of more than 7% can occur in the computation of direct normal irradiance from global hemispherical irradiance and diffuse hemispherical irradiance using these radiometers.

Myers, D. R.

2011-04-01T23:59:59.000Z

456

Quantifying the Earth Sciences: A Case for Improved Quantitative...  

NLE Websites -- All DOE Office Websites (Extended Search)

Meeting 5 Wyoming CCS Technology Institute total project funding: 1,895,786 DOE: 994,910 state match: 900,876 will be an administrative unit of UW's School...

457

Strangeness production in hadronic and quark matter: A quantitative differentiation  

SciTech Connect

We consider the production of strange particles in relativistic nucleus-nucleus collisions employing the hadron gas (HG) and quark-gluon plasma (QGP) formalism. We locate the region in the phase diagram where [mu][sub [ital s

Asprouli, M.N.; Panagiotou, A.D. (Physics Department, Nuclear Particle Physics Division, University of Athens, Panepistimiopolis, GR-157 71 Athens (Greece))

1995-02-01T23:59:59.000Z

458

Quantitative experiments in electric and fluid flow field mapping  

Science Conference Proceedings (OSTI)

A system employing a voltage probe attached to an XY recorder is used to sample the electrical potential over a grid of points on conducting paper. Using commercial plotting software

Richard A. Young

2001-01-01T23:59:59.000Z

459

Quantitative Comparison of the Responses of Three Floating Platforms  

DOE Green Energy (OSTI)

This report presents a comprehensive dynamic-response analysis of three offshore floating wind turbine concepts. Models were composed of one 5-MW turbine supported on land and three 5-MW turbines located offshore on a tension leg platform, a spar buoy, and a barge. A loads and stability analysis adhering to the procedures of international design standards was performed for each model using the fully coupled time-domain aero-hydro-servo-elastic design code FAST with AeroDyn and HydroDyn. The concepts are compared based on the calculated ultimate loads, fatigue loads, and instabilities. The results of this analysis will help resolve the fundamental design trade-offs between the floating-system concepts.

Jonkman, J.; Matha, D.

2010-03-01T23:59:59.000Z

460

Quantitative Comparison of the Responses of Three Floating Platforms  

NLE Websites -- All DOE Office Websites (Extended Search)

Commision MIT Massachusetts Institute of Technology NREL National Renewable Energy Laboratory O & G oil and gas O & M operations and maintenance OC3 Offshore Code...

Note: This page contains sample records for the topic "quantitative trait loci" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


461

Integration of novel SSR and gene-based SNP marker loci in the chickpea genetic map and establishment of new anchor points with Medicago truncatula genome  

E-Print Network (OSTI)

India Turkey Nepal Nepal Iran India Afghanistan TurkeyTurkey Lebanon Turkey Turkey Ethiopia Pakistan India IranIndia Iran Iran Iran Iran Unknown India India India India

2010-01-01T23:59:59.000Z

462

Tree species distribution in relation to stem hydraulic traits and soil moisture in a mixed hardwood forest in central Pennsylvania.  

E-Print Network (OSTI)

??The hydraulic architecture of a tree could contribute to its ability to tolerate drier soils by increasing resistance to xylem cavitation and improving the efficiency… (more)

Wubbels, Jane

2010-01-01T23:59:59.000Z

463

A physiological trait-based approach to predicting the responses of species to1 experimental climatic warming2  

E-Print Network (OSTI)

Street, Petersham, Massachusetts 01366 USA and 3 The Arnold Arboretum of Harvard University, 125 Arborway- erance. From June to August 2001 at Harvard Forest in Petersham, MA (42¢54 N, 72¢18 W) trees were

Sanders, Nathan J.

464

GENETIC AND ENVIRONMENTAL CONTROL OF MICROFIBRIL ANGLE ON Eucalyptus WOOD: ITS EFFECTS ON WOOD TRAITS AND IMPLICATION FOR SELECTION  

E-Print Network (OSTI)

I would like to thank many people who have assisted me to achieve this accomplishment, through encouragement and help along the way during my doctoral thesis at University of Montpellier 2. Financial support for the study was provided by CENIBRA, CIRAD and CNPq (Conselho Nacional de Desenvolvimento Científico e Tecnológico, Brazil). My scholarship was granted by CNPq through the process no. 200970/2008-9. Thanks also to the staff of the CIRAD teams Bois Tropicaux and Amélioration génétique et adaptation des plantes for technical, experimental and scientific support. Thanks to Departmento de Ciências Florestais, Universidade Federal de Lavras, Brazil, for experimental

Docteur De; Discipline Mécanique; Génie Civil; Paulo Ricardo; Gherardi Hein; M. Xxxxxxxx Président; M. Joseph; Gril Directeur Thèse; M. Jean-michel; M. Gilles; Chaix Examinateur; M. Loic; Brancheriau Examinateur; M. José; Tarcísio Lima Examinateur; M. Bruno; Clair Examinateur

2013-01-01T23:59:59.000Z

465

Prenatal versus postnatal sex steroid hormone effects on autistic traits in children at 18 to 24 months of age  

E-Print Network (OSTI)

SHORT REPORT T an important clue to the etiology of the condition, the development of ASC. This includes the finding that Auyeung et al. Molecular Autism 2012, 3:17 http://www.molecularautism.com/content/3/1/17This second peak may play a significant... role in physicalDouglas House, 18B Trumpington Rd, Cambridge CB2 8AH, UKFull list of author information is available at the end of the articlethough the true sex ratio in ASC is unclear given the known difficulties in the diagnosis of ASC in females [2...

Auyeung, Bonnie; Ahluwalia, Jag; Thomson, Lynn; Taylor, Kevin; Hackett, Gerald; O’Donnell, Kieran J; Baron-Cohen, Simon

2012-12-11T23:59:59.000Z

466

SHORT COMMUNICATION doi:10.1093/dnares/dsp005 Development of Genome-wide Simple Sequence Repeat Markers Using Whole-genome Shotgun Sequences of Sorghum (Sorghum bicolor (L.) Moench)  

E-Print Network (OSTI)

Simple sequence repeat (SSR) markers with a high degree of polymorphism contribute to the molecular dissection of agriculturally important traits in sorghum (Sorghum bicolor (L.) Moench). We designed 5599 non-redundant SSR markers, including regions flanking the SSRs, in whole-genome shotgun sequences of sorghum line ATx623. (AT/TA)n repeats constituted 26.1 % of all SSRs, followed by (AG/TC)n at 20.5%, (AC/TG)n at 13.7 % and (CG/GC)n at 11.8%. The chromosomal locations of 5012 SSR markers were determined by comparing the locations identified by means of electronic PCR with the predicted positions of 34 008 gene loci. Most SSR markers had a similar distribution to the gene loci. Among 970 markers validated by fragment analysis, 67.8 % (658 of 970) markers successfully provided PCR amplification in sorghum line BTx623, with a mean polymorphism rate of 45.1 % (297 of 658) for all SSR loci in combinations of 11 sorghum lines and one sudangrass (Sorghum sudanense (Piper) Stapf) line. The product of 5012 and 0.678 suggests that 3400 SSR markers could be used to detect SSR polymorphisms and that more than 1500 (45.1 % of 3400) markers could reveal SSR polymorphisms in combinations of Sorghum lines. Key words: sorghum (Sorghum bicolor (L.) Moench); simple sequence repeat (SSR); fragment analysis; genome-wide Sorghum (Sorghum bicolor (L.) Moench) is the world’s fifth most important cereal crop, after wheat, rice, maize and barley 1 and was grown on 43 million hectares in 2004

Jun-ichi Yonemaru; Tsuyu Ando; Tatsumi Mizubayashi; Shigemitsu Kasuga

2009-01-01T23:59:59.000Z

467

Quantitation of interfacial concentrations ofQuantitation of interfacial concentrations of biomacromolecules at the liquidbiomacromolecules at the liquid--liquid interfaceliquid interface  

E-Print Network (OSTI)

depth dp=80 nm · Oil layer: 50 micron thick oil layer on 0.8mm of water · Syringe pump controls infusion and Materials Science ** Department of Chemistry #12;OutlineOutline Studies of BSA-FITC adsorption at the oil/flow rate on protein relaxations at the oil-water and its implications on ultimate coverages Two

468

Optimizing energy yields in black locust through genetic selection: final report  

DOE Green Energy (OSTI)

The purpose of this work was to assess the magnitude of improvement in biomass yield of black locust possible through breeding, and to determine methods for efficiently capturing the yield improvement achievable from selective breeding. To meet this overall objective, six tasks were undertaken to determine: (1) the amount and geographic pattern of natural genetic variation, (2) the mating system of the species, (3) quantitative genetic parameters of relevant traits, (4) the relationship between nitrogen fixation and growth in black locust, (5) the viability of mass vegetative propagation, and (6) the feasibility of improvement through genetic transformation.

Bongarten, B.C.; Merkle, S.A. [Georgia Univ., Athens, GA (United States). School of Forest Resources

1996-10-01T23:59:59.000Z

469

Quantitative study of two- and three-dimensional strong localization of matter waves by atomic scatterers  

SciTech Connect

We study the strong localization of atomic matter waves in a disordered potential created by atoms pinned at the nodes of a lattice, for both three-dimensional (3D) and two-dimensional (2D) systems. The localization length of the matter wave, the density of localized states, and the occurrence of energy mobility edges (for the 3D system), are numerically investigated as a function of the effective scattering length between the atomic matter wave and the pinned atoms. Both positive and negative matter wave energies are explored. Interesting features of the density of states are discovered at negative energies, where maxima in the density of bound states for the system can be interpreted in terms of bound states of a matter wave atom with a few pinned atomic scatterers. In 3D we found evidence of up to three mobility edges, one at positive energies, and two at negative energies, the latter corresponding to transitions between extended and localized bound states. In 2D, no mobility edge is found, and a rapid exponential-like increase of the localization length is observed at high energy.

Antezza, Mauro; Castin, Yvan; Hutchinson, David A. W. [Laboratoire Kastler Brossel, Ecole Normale Superieure, CNRS and UPMC, 24 rue Lhomond, F-75231 Paris (France); Jack Dodd Centre for Quantum Technology, Department of Physics, University of Otago, Dunedin 9016 (New Zealand)

2010-10-15T23:59:59.000Z

470

Quantitative analysis of non-viral gene therapy in primary liver culture systems  

E-Print Network (OSTI)

Gene therapy has the potential to cure thousands of diseases caused by genetic abnormalities, provide novel combination therapies for cancers and viral infections, and offer a new and effective platform for next generation ...

Tedford, Nathan C

2007-01-01T23:59:59.000Z

471

Optimization of organelle fractionation methods for quantitative analysis of gene delivery trafficking kinetics  

E-Print Network (OSTI)

Nonviral vector research and development has been stunted by a lack of knowledge and understanding of how vectors are trafficked within the cell. Research currently involves mass screenings of different combinations of ...

Fang, Jennifer, M. Eng. Massachusetts Institute of Technology

2006-01-01T23:59:59.000Z

472

Development of quantitative methods for quality assessment of islets of Langerhans  

E-Print Network (OSTI)

Transplantation of isolated islets of Langerhans has promising potential to cure type 1 diabetes by inducing long-term normoglycemia and insulin independence. The feasibility of clinical islet transplantations has been ...

Pisania, Anna

2007-01-01T23:59:59.000Z

473

Quantitative laboratory measurements of biogeochemical processes controlling biogenic calcite carbon sequestration.  

Science Conference Proceedings (OSTI)

The purpose of this LDRD was to generate data that could be used to populate and thereby reduce the uncertainty in global carbon cycle models. These efforts were focused on developing a system for determining the dissolution rate of biogenic calcite under oceanic pressure and temperature conditions and on carrying out a digital transcriptomic analysis of gene expression in response to changes in pCO2, and the consequent acidification of the growth medium.

Zendejas, Frank; Lane, Todd W.; Lane, Pamela D.

2011-01-01T23:59:59.000Z

474

We are not dead . . . - The quantitative theory and the relation between money and inflation .  

E-Print Network (OSTI)

??This paper presents a robust finding for the relationship between money growth and inflation in Chile: inflation causes (precedes) money and not the other way… (more)

Chumacero Escudero, Rómulo Augusto

2007-01-01T23:59:59.000Z

475

Quantitative comparison between Type Ia supernova spectra at low and high redshifts: A case study  

E-Print Network (OSTI)

Propulsion Laboratory, California Institute of Technology, under contract with the National Aeronautics and Space

Garavini, G.; Supernova Cosmology Project

2008-01-01T23:59:59.000Z

476

A quantitative model of transcriptional regulation reveals the influence binding location on expression  

E-Print Network (OSTI)

Understanding the mechanistic basis of transcriptional regulation has been a central focus of molecular biology since its inception. New high-throughput chromatin immunoprecipitation experiments have revealed that most ...

MacIsaac, Kenzie Daniel

477

A Quantitative Analysis of Pricing Behavior In California's Wholesale Electricity Market During Summer 2000  

E-Print Network (OSTI)

in Northern California, gas-fired steam and peaking turbines, and cogenerators and other generation sources that are ?Qualifying Facilities? (QFs) under the Public Utility Regulatory Policy Act of 1978 (PURPA). About half of in-state generating capacity... to as ?de-rating? the nominal capacity of units to a ?firm? capacity level. The forced outage rates for the gas plants are in