National Library of Energy BETA

Sample records for organisms synthetic biology

  1. Synthesizing Law for Synthetic Biology

    E-Print Network [OSTI]

    Torrance, Andrew W.

    2010-01-01

    , metabolic pathways, cells, viruses, and whole organisms rapidly, inexpensively, and easily. Already, a number of institutions have helped synthetic biology achieve considerable success, both in terms of science and public awareness. The BioBricks Foundation...

  2. Authentic teaching and learning through synthetic biology

    E-Print Network [OSTI]

    Kuldell, Natalie

    Synthetic biology is an emerging engineering discipline that, if successful, will allow well-characterized biological components to be predictably and reliably built into robust organisms that achieve specific functions. ...

  3. Research Councils UK Synthetic biology

    E-Print Network [OSTI]

    Crowther, Paul

    Research Councils UK Synthetic biology #12;Synthetic biology Research funded by the Research a variety of approaches to support innovation and deliver impact from research, including the development of collaborative research programmes, investment in major research capabilities, such as national research

  4. Synthetic biology and crop engineering

    Broader source: Energy.gov [DOE]

    Breakout Session 2: Frontiers and Horizons Session 2-A: Synthetic Biology and the Promise of Biofuels Jonathan Burbaum, Program Director, Department of Energy, Office of Science, ARPA–E

  5. 2003 Synthetic Biology study

    E-Print Network [OSTI]

    Endy, Drew

    2007-08-14

    Biology is a technology for processing information, materials, and energy. As a technology platform, biological systems provide access to artifacts and processes across a range of scales (e.g., the ribosome is a programmable ...

  6. Computational Modelling in Systems and Synthetic Biology

    E-Print Network [OSTI]

    Romero-Campero, Francisco J.

    modules Networks Cells Colonies Systems Biology and Synthetic Biology #12;Stochasticity is important processes. Executable semantics. o Modularity in cellular systems, especially in gene regulatory networks been successfully applied. Monika Heiner, David Gilbert, Robin Donaldson. Petri Nets for Systems

  7. Foundational platform for mammalian synthetic biology

    E-Print Network [OSTI]

    Davidsohn, Noah (Noah Justin)

    2013-01-01

    The emergent field of synthetic biology is different from many other biological engineering efforts, in that its roots, design principles, and forward engineering perspective have been adopted from electrical engineering ...

  8. Synthetic Biology for Therapeutic Applications Zhanar Abil,

    E-Print Network [OSTI]

    Zhao, Huimin

    Synthetic Biology for Therapeutic Applications Zhanar Abil, Xiong Xiong, and Huimin Zhao of Bioengineering, Department of Chemistry, Center for Biophysics and Computational Biology and Institute for Genomic Biology, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana, Illinois

  9. Aspects of the political economy of development and synthetic biology

    E-Print Network [OSTI]

    Wellhausen, Rachel

    What implications might synthetic biology’s potential as a wholly new method of production have for the world economy, particularly developing countries? Theories of political economy predict that synthetic biology can ...

  10. A modelling framework for Synthetic Biology

    E-Print Network [OSTI]

    in large gene compositions. Keywords: Synthetic biology; Gene regulated networks; Stochastic simulation; Petri net modelling; Genetic design automation; Genetic logic synthesis #12;ii #12;Summary (Danish gensammensætninger. Nøgleord: Syntesebiologi; Genregulerede netværk; Stokastisk simulering; Petri net mo- dellering

  11. Micro/nanofabricated environments for synthetic biology

    SciTech Connect (OSTI)

    Collier, Pat [ORNL; Simpson, Michael L [ORNL

    2011-01-01

    A better understanding of how confinement, crowding and reduced dimensionality modulate reactivity and reaction dynamics will aid in the rational and systematic discovery of functionality in complex biological systems. Artificial micro- and nanofabricated structures have helped elucidate the effects of nanoscale spatial confinement and segregation on biological behavior, particularly when integrated with microfluidics, through precise control in both space and time of diffusible signals and binding interactions. Examples of nanostructured interfaces for synthetic biology include the development of cell-like compartments for encapsulating biochemical reactions, nanostructured environments for fundamental studies of diffusion, molecular transport and biochemical reaction kinetics, and regulation of biomolecular interactions as functions of micro- and nanofabricated topological constraints.

  12. Synthetic approaches to understanding biological constraints

    E-Print Network [OSTI]

    Velenich, Andrea

    Microbes can be readily cultured and their genomes can be easily manipulated. For these reasons, laboratory systems of unicellular organisms are increasingly used to develop and test theories about biological constraints, ...

  13. Modular languages for systems and synthetic biology 

    E-Print Network [OSTI]

    Pedersen, Michael

    2010-01-01

    Systems biology is a rapidly growing field which seeks a refined quantitative understanding of organisms, particularly studying how molecular species such as metabolites, proteins and genes interact in cells to form the ...

  14. What rough beast? Synthetic Biology and the Future of Biosecurity

    E-Print Network [OSTI]

    Mohr, Scott C.

    Synthetic biology seeks to create modular biological parts that can be assembled into useful devices, allowing the modification of biological systems with greater reliability, at lower cost, with greater speed, and by a ...

  15. Copy of Synthetic Biology of Novel Thermophilic Bacteria for...

    Office of Scientific and Technical Information (OSTI)

    Copy of Synthetic Biology of Novel Thermophilic Bacteria for Enhanced Production of Ethanol from 5-Carbon Sugars (LDRD %23 105944). Citation Details In-Document Search Title: Copy...

  16. Controlled polymer synthesis--from biomimicry towards synthetic biology

    E-Print Network [OSTI]

    Davis, Ben G.

    Controlled polymer synthesis--from biomimicry towards synthetic biology George Pasparakis assembly of synthetic polymer structures is now possible with an unprecedented range of functional groups). Introduction Life depends on polymers, and the adage `the whole is greater than the sum of the parts

  17. Amino : a domestic system for synthetic biology and continuous culturing

    E-Print Network [OSTI]

    Legault, Julie, S.M. Massachusetts Institute of Technology

    2015-01-01

    With the ability to transfer a trait from one creature to another purposefully, synthetic biology is advancing across unforeseen domains. From algae cells that convert carbon dioxide to fuel, biocementation bacteria to ...

  18. Defossiling Fuel: How Synthetic Biology Can Transform Biofuel Production

    E-Print Network [OSTI]

    Defossiling Fuel: How Synthetic Biology Can Transform Biofuel Production David F. Savage , Jeffrey through natural intermediates to final molecule is long, and biofuel production is perhaps the ultimate engineering, economic, political, and environmental realities. Are biofuels sustainable? Consider U

  19. The Evolutionary Systems Biology Team Synthetic Biology/Citizen Science Post-doctoral position

    E-Print Network [OSTI]

    The Evolutionary Systems Biology Team Synthetic Biology/Citizen Science Post-doctoral position We in citizen science projects.The post-doc will join the extended CRI lab that includes synthetic and systems-sourcing, DIY approaches and gamification as part of a new European- funded project, Citizen CyberLab - a three

  20. Renewable Energy from Synthetic Biology (LBNL Science at the Theater)

    ScienceCinema (OSTI)

    Keasling, Jay

    2011-04-28

    Jay Keasling, co-leader of Berkeley Lab's Helios Project, is a groundbreaking researcher in the new scientific field of synthetic biology. In Helios, he directs the biology program, incorporating a range of approaches to increasing the efficacy and economy of plants and cellulose-degrading microbes to make solar-based fuels. He is a UC Berkeley professor of Chemical and Bioengineering, and founder of Amyris Biotechnologies, a company that was honored as a Technology Pioneer for 2006 by the World Economic Forum. Keasling has succeeded in using synthetic biology to develop a yeast-based production scheme for precursors of the antimalarial drug artemisinin in work funded by the Bill & Melinda Gates Foundation.

  1. Synthetic Biology: Engineering, Evolution and Design (SEED) Conference 2014

    SciTech Connect (OSTI)

    Voigt, Christopher

    2014-07-01

    SEED2014 focused on advances in the science and technology emerging from the field of synthetic biology. We broadly define this as technologies that accelerate the process of genetic engineering. It highlighted new tool development, as well as the application of these tools to diverse problems in biotechnology, including therapeutics, industrial chemicals and fuels, natural products, and agriculture. Systems spanned from in vitro experiments and viruses, through diverse bacteria, to eukaryotes (yeast, mammalian cells, plants).

  2. Synthetic biological membrane with self organizing properties

    DOE Patents [OSTI]

    Firestone, Millicent A. (Elmhurst, IL); Tiede, David M. (Elmhurst, IL)

    2003-01-01

    A mixture is provided which manifests a gel phase at a temperature higher than that in which the mixture manifests a liquid phase. The mixture is a combination of a lipid, a polymer-grafted phospholipid and a surfactant. It is biomimetic in nature and changes phases when subjected to one or a plurality of environmental stimuli.

  3. Safe, secure and ethical? : assessing and regulating risks associated with synthetic biology

    E-Print Network [OSTI]

    Regårdh, Pernilla C. (Pernilla Christina)

    2011-01-01

    Synthetic biology is an emerging field, with a rapidly developing academic-industrial base and the promise of extensive product launches over the next few years. An intense debate over the risks and benefits of synthetic ...

  4. Synthetic Biology and the U.S. Biotechnology Regulatory System: Challenges and Options

    SciTech Connect (OSTI)

    Carter, Sarah R.; Rodemeyer, Michael; Garfinkel, Michele S.; Friedman, Robert M

    2014-05-01

    Synthetic Biology and the U.S. Biotechnology Regulatory System: Challenges and Options Sarah R. Carter, Ph.D., J. Craig Venter Institute; Michael Rodemeyer, J.D., University of Virginia; Michele S. Garfinkel, Ph.D., EMBO; Robert M. Friedman, Ph.D., J. Craig Venter Institute In recent years, a range of genetic engineering techniques referred to as “synthetic biology” has significantly expanded the tool kit available to scientists and engineers, providing them with far greater capabilities to engineer organisms than previous techniques allowed. The field of synthetic biology includes the relatively new ability to synthesize long pieces of DNA from chemicals, as well as improved methods for genetic manipulation and design of genetic pathways to achieve more precise control of biological systems. These advances will help usher in a new generation of genetically engineered microbes, plants, and animals. The JCVI Policy Center team, along with researchers at the University of Virginia and EMBO, examined how well the current U.S. regulatory system for genetically engineered products will handle the near-term introduction of organisms engineered using synthetic biology. In particular, the focus was on those organisms intended to be used or grown directly in the environment, outside of a contained facility. The study concludes that the U.S. regulatory agencies have adequate legal authority to address most, but not all, potential environmental, health and safety concerns posed by these organisms. Such near-term products are likely to represent incremental changes rather than a marked departure from previous genetically engineered organisms. However, the study also identified two key challenges for the regulatory system, which are detailed in the report. First, USDA’s authority over genetically engineered plants depends on the use of an older engineering technique that is no longer necessary for many applications. The shift to synthetic biology and other newer genetic engineering techniques will leave many engineered plants without any pre-market regulatory review. Second, the number and diversity of engineered microbes for commercial use will increase in the near future, challenging EPA’s resources, expertise, and perhaps authority to regulate them. For each of these challenges, the report sets out a series of options, including an analysis of the advantages and disadvantages of each option from a variety of perspectives, for policy makers to consider. Policy responses will depend on the trade-offs chosen among competing considerations. This report, funded by the Department of Energy with additional funds from the Alfred P. Sloan Foundation, is the result of a two-year process that included interviews, commissioned background papers, discussions, and two workshops that sought input from a wide range of experts, including U.S. federal agency regulators, legal and science policy experts, representatives from the biotechnology indus¬try, and non-governmental organiza¬tions. This cross-section of views informed this report, but the conclusions are solely those of the authors. An Executive Summary, full Report, and background papers are available at: http://www.jcvi.org/cms/research/projects/synthetic-biology-and-the-us-biotechnology-regulatory-system/overview/

  5. Uncertainty in synthetic biology for release and possibilities for regulation under the Toxic Substances Control Act

    E-Print Network [OSTI]

    Lightfoot, Shlomiya

    2014-01-01

    The emerging field of synthetic biology is developing rapidly and promises diverse applications. Many anticipated applications, particularly those involving release of engineered microbes into the environment or human ...

  6. future science group 9ISSN 1759-726910.4155/BFS.11.151 2012 Future Science Ltd Synthetic biology approaches to biofuel production

    E-Print Network [OSTI]

    Hasty, Jeff

    approaches to biofuel production Editorial Biofuels (2012) 3(1), 9­12 "...it is important for synthetic will focus on the use of synthetic biology to engineer organisms for the more efficient production of biofuel over the current production level of about 13 billion gallons [1]. Given the expanding mar- ket

  7. Tools and reference standards supporting the engineering and evolution of synthetic biological systems

    E-Print Network [OSTI]

    Kelly, Jason R. (Jason Robert)

    2008-01-01

    Biological engineers have constructed a number of multi-part synthetic biological systems that conduct logical operations on input signals, produce oscillatory output signals, store memory, or produce desired products. ...

  8. Biological Hydrogen Production Using Synthetic Wastewater Biotin and glutamic acid are not required for biological hydrogen production.

    E-Print Network [OSTI]

    Barthelat, Francois

    Biological Hydrogen Production Using Synthetic Wastewater Conclusion ·Biotin and glutamic acid are not required for biological hydrogen production. ·MgSO4 .7H2O is a required nutrient, but hydrogen production work should focus on minimizing the lag time in biological hydrogen production, by varying nutrient

  9. Strategies for designing, testing and demonstrating safety : what synthetic biology can learn from retrospective cases

    E-Print Network [OSTI]

    Yeddanapudi, Neelima, 1976-

    2009-01-01

    Synthetic biology is an emerging technology field within the realm of genetic engineering, differing from traditional genetic engineering in that it focuses on the modularization of genetic parts and the creation of de ...

  10. A Case Study in Model-driven Synthetic Biology

    E-Print Network [OSTI]

    Gilbert, D.R.; Heiner, M.; Rosser, S.; Fulton, F.; Gu, X.; Trybilo, M.; Biologically Inspired Cooperative Computing: BICC 2008 IFIP [More Details

    Gilbert,D.R. Heiner,M. Rosser,S. Fulton,F. Gu,X. Trybilo,M. Biologically Inspired Cooperative Computing: BICC 2008 IFIP

  11. Landauer in the age of synthetic biology: energy consumption and information processing in biochemical networks

    E-Print Network [OSTI]

    Mehta, Pankaj; Schwab, David J

    2015-01-01

    A central goal of synthetic biology is to design sophisticated synthetic cellular circuits that can perform complex computations and information processing tasks in response to specific inputs. The tremendous advances in our ability to understand and manipulate cellular information processing networks raises several fundamental physics questions: How do the molecular components of cellular circuits exploit energy consumption to improve information processing? Can one utilize ideas from thermodynamics to improve the design of synthetic cellular circuits and modules? Here, we summarize recent theoretical work addressing these questions. Energy consumption in cellular circuits serves five basic purposes: (1) increasing specificity, (2) manipulating dynamics, (3) reducing variability, (4) amplifying signal, and (5) erasing memory. We demonstrate these ideas using several simple examples and discuss the implications of these theoretical ideas for the emerging field of synthetic biology. We conclude by discussing h...

  12. Challenges and opportunities in synthetic biology for chemical engineers Yunzi Luo a

    E-Print Network [OSTI]

    Zhao, Huimin

    Challenges and opportunities in synthetic biology for chemical engineers Yunzi Luo a , Jung-Kul Lee c , Huimin Zhao a,b,n a Department of Chemical and Biomolecular Engineering, University of Illinois, United States c Department of Chemical Engineering, Konkuk University, Seoul 143-701, South Korea H I G H

  13. Synthetic and Mechanistic Chemistry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    isotopes for biological applications Aaron S. Anderson: Synthetic chemistry of biosensors Andrew M. Dattelbaum: Synthetic chemistry and nanoparticles Sponsors, Funding...

  14. Part Mining for Synthetic Biology (2013 DOE JGI Genomics of Energy and Environment 8th Annual User Meeting)

    SciTech Connect (OSTI)

    Voigt, Chris [MIT

    2013-03-01

    Chris Voigt from MIT delivers the opening keynote on "Part Mining for Synthetic Biology" at the 8th Annual Genomics of Energy & Environment Meeting on March 26, 2013 in Walnut Creek, Calif.

  15. Bridging gaps in synthetic biology oversight : iGEM as a testbed for proactive, adaptive risk management

    E-Print Network [OSTI]

    McNamara, Julie H. (Julie Hutton)

    2014-01-01

    On the surface, the emerging field of synthetic biology looks highly similar to that of genetic engineering. However, the two fields are based upon divergent underlying logic structures. Whereas genetic engineering affects ...

  16. Systems Biology of Organs on a Chip John Wikswo

    E-Print Network [OSTI]

    Wikswo, John

    1 Systems Biology of Organs on a Chip John Wikswo Fall, 2013 Undergraduates: PHYS 240 01 and BME 290B -- SpTp: Systems Biology Graduate students: PHYS 326 Theoretical and Experimental Systems Biology BME 395C -- SpTp: Systems Biology Meeting times: 2:35 ­ 3:50 Tuesdays and Thursdays, SC6837

  17. Metabolic engineering of microorganisms for biofuels production: from bugs to synthetic biology to fuels

    SciTech Connect (OSTI)

    Kuk Lee, Sung; Chou, Howard; Ham, Timothy S.; Soon Lee, Taek; Keasling, Jay D.

    2009-12-02

    The ability to generate microorganisms that can produce biofuels similar to petroleum-based transportation fuels would allow the use of existing engines and infrastructure and would save an enormous amount of capital required for replacing the current infrastructure to accommodate biofuels that have properties significantly different from petroleum-based fuels. Several groups have demonstrated the feasibility of manipulating microbes to produce molecules similar to petroleum-derived products, albeit at relatively low productivity (e.g. maximum butanol production is around 20 g/L). For cost-effective production of biofuels, the fuel-producing hosts and pathways must be engineered and optimized. Advances in metabolic engineering and synthetic biology will provide new tools for metabolic engineers to better understand how to rewire the cell in order to create the desired phenotypes for the production of economically viable biofuels.

  18. Crystalline guanine adducts of natural and synthetic trioxacarcins suggest a common biological mechanism and reveal a basis

    E-Print Network [OSTI]

    Crystalline guanine adducts of natural and synthetic trioxacarcins suggest a common biological effects, with the self-complimentary duplex oligonucleotide d(AACCGGTT) led to production of a crystalline-red crystalline guanine adduct (7) from incubation of trioxacarcin A itself with the self- complimentary duplex

  19. Metabolic Engineering and Synthetic Biology in Strain Development Every year, we consume about 27 billion barrels of fossil oil.

    E-Print Network [OSTI]

    Metabolic Engineering and Synthetic Biology in Strain Development Every year, we consume about 27, such as shale gas, are becoming available as new energy and chemical sources, these fossil resources will not be available in the future, simply because we consume them at a much higher rate than the rate at which

  20. Chemistry Major's Guide FA12/SP13 (Revised 5/14/12) 7 Recommended Academic Plan Synthetic/Biological Concentration

    E-Print Network [OSTI]

    Babu, G. Jogesh

    Chemistry Major's Guide FA12/SP13 (Revised 5/14/12) 7 Recommended Academic Plan ­ Synthetic/Biological Concentration Semester 1 Credits Semester 2 Credits PSU 16 Freshman Seminar in Chemistry 1 CHEM 112(H) Chemical Principles II (GN) 3 CHEM 110(H) Chemical Principles I (GN) 3 CHEM 113 Experimental Chemistry II

  1. C H A P T E R F O U R T E E N Microfluidics for Synthetic Biology

    E-Print Network [OSTI]

    Hasty, Jeff

    C H A P T E R F O U R T E E N Microfluidics for Synthetic Biology: From Design to Execution M. S of a microfluidic chip 298 1.2. A parallel DAW device 322 1.3. Cell tracking 326 1.4. DAW hardware and software 334. coli 358 3.2. Method to set up a MDAW microfluidic experiment 364 Acknowledgments 371 References 371

  2. Green Algae as Model Organisms for Biological Fluid Dynamics

    E-Print Network [OSTI]

    Raymond E. Goldstein

    2014-09-08

    In the past decade the volvocine green algae, spanning from the unicellular $Chlamydomonas$ to multicellular $Volvox$, have emerged as model organisms for a number of problems in biological fluid dynamics. These include flagellar propulsion, nutrient uptake by swimming organisms, hydrodynamic interactions mediated by walls, collective dynamics and transport within suspensions of microswimmers, the mechanism of phototaxis, and the stochastic dynamics of flagellar synchronization. Green algae are well suited to the study of such problems because of their range of sizes (from 10 $\\mu$m to several millimetres), their geometric regularity, the ease with which they can be cultured and the availability of many mutants that allow for connections between molecular details and organism-level behavior. This review summarizes these recent developments and highlights promising future directions in the study of biological fluid dynamics, especially in the context of evolutionary biology, that can take advantage of these remarkable organisms.

  3. Synthetic Metagenomics: Converting digital information back to Biology (2013 DOE JGI Genomics of Energy and Environment 8th Annual User Meeting)

    SciTech Connect (OSTI)

    Deutsch, Sam [DOE Joint Genome Institute

    2013-03-01

    Sam Deutsch of the DOE JGI on "Synthetic Metagenomics: Converting digital information back to Biology" at the 8th Annual Genomics of Energy & Environment Meeting in Walnut Creek, Calif.

  4. Green Algae as Model Organisms for Biological Fluid Dynamics

    E-Print Network [OSTI]

    Goldstein, Raymond E

    2014-01-01

    In the past decade the volvocine green algae, spanning from the unicellular $Chlamydomonas$ to multicellular $Volvox$, have emerged as model organisms for a number of problems in biological fluid dynamics. These include flagellar propulsion, nutrient uptake by swimming organisms, hydrodynamic interactions mediated by walls, collective dynamics and transport within suspensions of microswimmers, the mechanism of phototaxis, and the stochastic dynamics of flagellar synchronization. Green algae are well suited to the study of such problems because of their range of sizes (from 10 $\\mu$m to several millimetres), their geometric regularity, the ease with which they can be cultured and the availability of many mutants that allow for connections between molecular details and organism-level behavior. This review summarizes these recent developments and highlights promising future directions in the study of biological fluid dynamics, especially in the context of evolutionary biology, that can take advantage of these re...

  5. Theory: Biological systems organize to maximize entropy production subject to information and biophysicochemical constraints.

    E-Print Network [OSTI]

    Vallino, Joseph J.

    Theory: Biological systems organize to maximize entropy production subject to information: biological systems store information within their metagenome. Therefore, we propose that abiotic systems that biological systems with greater information content will have higher entropy production rates than biological

  6. Approaches to mitigate the impact of dissolved organic matter on the adsorption of synthetic organic contaminants by porous carbonaceous sorbents

    SciTech Connect (OSTI)

    Yanping Guo; Abhishek Yadav; Tanju Karanfil [Clemson University, Anderson, SC (United States). Department of Environmental Engineering and Earth Sciences

    2007-11-15

    Adsorption of trichloroethylene (TCE) and atrazine, two synthetic organic contaminants (SOCs) having different optimum adsorption pore regions, by four activated carbons and an activated carbon fiber (ACF) was examined. Adsorbents included two coconut-shell based granular activated carbons (GACs), two coal-based GACs (F400 and HD4000) and a phenol formaldehyde-based activated carbon fiber. The selected adsorbents had a wide range of pore size distributions but similar surface acidity and hydrophobicity. Single solute and preloading (with a dissolved organic matter (DOM)) isotherms were performed. Single solute adsorption results showed that (i) the adsorbents having higher amounts of pores with sizes about the dimensions of the adsorbate molecules exhibited higher uptakes, (ii) there were some pore structure characteristics, which were not completely captured by pore size distribution analysis, that also affected the adsorption, and (iii) the BET surface area and total pore volume were not the primary factors controlling the adsorption of SOCs. The preloading isotherm results showed that for TCE adsorbing primarily in pores <10 {angstrom}, the highly microporous ACF and GACs, acting like molecular sieves, exhibited the highest uptakes. For atrazine with an optimum adsorption pore region of 10-20 {angstrom}, which overlaps with the adsorption region of some DOM components, the GACs with a broad pore size distribution and high pore volumes in the 10-20 {angstrom} region had the least impact of DOM on the adsorption. 25 refs., 3 figs., 3 tabs.

  7. New Synthetic Methods for Hypericum Natural Products

    SciTech Connect (OSTI)

    Insik Jeon

    2006-12-12

    Organic chemistry has served as a solid foundation for interdisciplinary research areas, such as molecular biology and medicinal chemistry. An understanding of the biological activities and structural elucidations of natural products can lead to the development of clinically valuable therapeutic options. The advancements of modern synthetic methodologies allow for more elaborate and concise natural product syntheses. The theme of this study centers on the synthesis of natural products with particularly challenging structures and interesting biological activities. The synthetic expertise developed here will be applicable to analog syntheses and to other research problems.

  8. Synthetic hepcidin causes rapid dose-dependent hypoferremia and is concentrated in ferroportin-containing organs

    E-Print Network [OSTI]

    Rivera, Seth; Nemeth, E; Gabayan, V; Lopez, M A; Farshidi, D; Ganz, T

    2005-01-01

    M). 8 Figure 1. Hepcidin causes a dose-dependent fall inNUMBER 6 Figure 3. Hepcidin causes a rapid, sustained fallRED CELLS Synthetic hepcidin causes rapid dose-dependent

  9. Single nanopore transport of synthetic and biological polyelectrolytes in three-dimensional hybrid microfluidic/nanofluidic devices

    SciTech Connect (OSTI)

    King, Travis L. [Univ. of Illinois at Urbana-Champaign, IL (United States). Dept. of Chemistry; Univ. of Notre Dame, South Bend, IN (United States). Dept. of Chemical and Biomolecular Engineering; Gatimu, Enid N. [Univ. of Notre Dame, South Bend, IN (United States). Dept. of Chemical and Biomolecular Engineering; Bohn, Paul W. [Univ. of Notre Dame, South Bend, IN (United States). Dept. of Chemical and Biomolecular Engineering, Dept. of Chemistry and Biochemistry

    2009-01-01

    This paper presents a study of electrokinetic transport in single nanopores integrated into vertically-stacked three-dimensional hybrid microfluidic/nanofluidic structures. In these devices single nanopores, created by focused ion beam (FIB) milling in thin polymer films, provide fluidic connection between two vertically separated, perpendicular microfluidic channels. Experiments address both systems in which the nanoporous membrane is composed of the same (homojunction) or different (heterojunction) polymer as the microfluidic channels. These devices are then used to study the electrokinetic transport properties of synthetic (i.e., polystyrene sulfonate and polyallylamine) and biological (i.e.,DNA) polyelectrolytes across these nanopores. Single nanopore transport of polyelectrolytes across these nanopores using both electrical current measurements and confocal microscopy. Both optical and electrical measurements indicate that electroosmotic transport is predominant over electrophoresis in single nanopores with d > 180 nm, consistent with results obtained under similar conditions for nanocapillary array membranes.

  10. Single nanopore transport of synthetic and biological polyelectrolytes in three-dimensional hybrid microfluidic/nanofluidic devices

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    King, Travis L.; Gatimu, Enid N.; Bohn, Paul W.

    2009-01-02

    This paper presents a study of electrokinetic transport in single nanopores integrated into vertically-stacked three-dimensional hybrid microfluidic/nanofluidic structures. In these devices single nanopores, created by focused ion beam (FIB) milling in thin polymer films, provide fluidic connection between two vertically separated, perpendicular microfluidic channels. Experiments address both systems in which the nanoporous membrane is composed of the same (homojunction) or different (heterojunction) polymer as the microfluidic channels. These devices are then used to study the electrokinetic transport properties of synthetic (i.e., polystyrene sulfonate and polyallylamine) and biological (i.e.,DNA) polyelectrolytes across these nanopores. Single nanopore transport of polyelectrolytes across these nanoporesmore »using both electrical current measurements and confocal microscopy. Both optical and electrical measurements indicate that electroosmotic transport is predominant over electrophoresis in single nanopores with d > 180 nm, consistent with results obtained under similar conditions for nanocapillary array membranes.« less

  11. Application of novel methods using synthetic biology tools to investigate solvent toxicity in bacteria 

    E-Print Network [OSTI]

    Fletcher, Eugene Kobina Arhin

    2014-06-28

    Toxicity of organic solvents to microbial hosts is a major consideration in the economical production of biofuels such as ethanol and especially butanol, with low product concentrations leading to high recovery costs. ...

  12. Synthetic and organic fungicide control of apple scab: 2009 field trial

    E-Print Network [OSTI]

    Janousek, Christopher N; Bay, Ian S; Gubler, W. Douglas

    2009-01-01

    during leaf fall to control apple scab (Venturia inaequalis)mixtures on scab control in apple orchards. Plant Pathologyscab development in an organic apple orchard. Agriculture,

  13. An Imaging Roadmap for Biology Education: From Nanoparticles to Whole Organisms

    E-Print Network [OSTI]

    Wisconsin at Madison, University of

    Article An Imaging Roadmap for Biology Education: From Nanoparticles to Whole Organisms Daniel J in the biology curriculum. Guided by the National Institutes of Health (NIH) Roadmap initiatives, we incorporated of an introductory course on ways of knowing biology. Activities were derived from NIH Roadmap initiatives

  14. Chemistry/Biology Interface Training Program (CBITG) Goals of the Program and Rationale for the Program Organization

    E-Print Network [OSTI]

    Thomas, David D.

    2011 Chemistry/Biology Interface Training Program (CBITG) Goals of the Program and Rationale recruited by the Chemistry, BMBB, Medicinal Chemistry and Microbiology Departments, at a stage of interest (e.g., synthetic/mechanistic chemistry, molecular biology, mechanistic enzymology, medicinal

  15. Organic and Printed Electronics for Biological Microfluidic Applications

    E-Print Network [OSTI]

    Jagannathan, Lakshmi

    2012-01-01

    low-cost and flexible substrates. Printed electronics alsoflexible and plastic substrates Table 1. Comparison between conventional processing and processing using printed electronics.flexible substrates. Specifically, for biological applications, the ability of printed electronics

  16. Nanomechanical properties of hydrated organic thin films

    E-Print Network [OSTI]

    Choi, Jae Hyeok

    2007-01-01

    Hydrated organic thin films are biological or synthetic molecularly thin coatings which impart a particular functionality to an underlying substrate and which have discrete water molecules associated with them. Such films ...

  17. BIOL/MATH 393 Synthetic Biology Professors: Dr. Kristin O'Brien, kmobrien@alaska.edu, 474-5311

    E-Print Network [OSTI]

    Ickert-Bond, Steffi

    : Microbes that convert corn into plastic; a microbial fuel cell that generates electricity; E. coli bacteria that synthesize hemoglobin used for blood transfusions; E. coli that sense and destroy cancer cells- all. They will work together to design a synthetic microbe, construct the microbe and present results to the class

  18. What is compost? Composting refers to biological decomposition and stabilization of organic materials by microorganisms under

    E-Print Network [OSTI]

    Mukhtar, Saqib

    What is compost? Composting refers to biological decomposition and stabilization of organic materials by microorganisms under aerobic conditions (in the presence of oxygen). During the composting is production of good-quality compost that is biologically stable, relatively uniform in appearance, free

  19. LANL organic analysis detection capabilities for chemical and biological warfare agents

    SciTech Connect (OSTI)

    Ansell, G.B.; Cournoyer, M.E.; Hollis, K.W.; Monagle, M.

    1996-12-31

    Organic analysis is the analytical arm for several Los Alamos National Laboratory (LANL) research programs and nuclear materials processes, including characterization and certification of nuclear and nonnuclear materials used in weapons, radioactive waste treatment and waste certification programs. Organic Analysis has an extensive repertoire of analytical technique within the group including headspace gas, PCBs/pesticides, volatile organics and semivolatile organic analysis. In addition organic analysis has mobile labs with analytic capabilities that include volatile organics, total petroleum hydrocarbon, PCBs, pesticides, polyaromatic hydrocarbons and high explosive screening. A natural extension of these capabilities can be applied to the detection of chemical and biological agents,

  20. Photoconversion of gasified organic materials into biologically-degradable plastics

    DOE Patents [OSTI]

    Weaver, P.F.; Pinching Maness.

    1993-10-05

    A process is described for converting organic materials (such as biomass wastes) into a bioplastic suitable for use as a biodegradable plastic. In a preferred embodiment the process involves thermally gasifying the organic material into primarily carbon monoxide and hydrogen, followed by photosynthetic bacterial assimilation of the gases into cell material. The process is ideally suited for waste recycling and for production of useful biodegradable plastic polymer. 3 figures.

  1. Photoconversion of gasified organic materials into biologically-degradable plastics

    DOE Patents [OSTI]

    Weaver, Paul F. (Golden, CO); Maness, Pin-Ching (Golden, CO)

    1993-01-01

    A process is described for converting organic materials (such as biomass wastes) into a bioplastic suitable for use as a biodegradable plastic. In a preferred embodiment the process involves thermally gasifying the organic material into primarily carbon monoxide and hydrogen, followed by photosynthetic bacterial assimilation of the gases into cell material. The process is ideally suited for waste recycling and for production of useful biodegradable plastic polymer.

  2. Fibrillar Organic Phases And Their Roles In Rigid Biological Composites

    SciTech Connect (OSTI)

    Arey, Bruce W.; Park, John J.; Mayer, George

    2015-06-01

    This study focused on determining the presence of organic phases in the siliceous components of rigid marine composites ("glass" sponge spicules), and thereby to clarify how those composites dissipate significant mechanical energy. Through the use of imaging by helium ion microscopy in the examination of the spicules, the organic phase that is present between the layers of hydrated silica was also detected within the silica cylinders of the composite, indicating the existence therein of a network, scaffolding, or other pattern that has not yet been determined. It was concluded that the presence of an interpenetrating network of some kind, and tenacious fibrillar interfaces are responsible for the large energy dissipation in these siliceous composites by viscoelastic processes. This discovery means that future mechanics analyses of such composites, extending to large deformations must consider such interpenetrating phases.

  3. Journal of Theoretical Biology 241 (2006) 823829 Exploring local structural organization of metabolic

    E-Print Network [OSTI]

    Jeong, Hawoong

    2006-01-01

    follow the long-tailed power law and show the small-world property. In addition, their modular structuresJournal of Theoretical Biology 241 (2006) 823­829 Exploring local structural organization cells to produce energy or to build various molecules. The sum of all these chemical reactions within

  4. Soil Biology & Biochemistry 38 (2006) 22922299 Modifications of degradation-resistant soil organic matter by soil

    E-Print Network [OSTI]

    Miksik, Ivan

    2006-01-01

    Soil Biology & Biochemistry 38 (2006) 2292­2299 Modifications of degradation-resistant soil organic matter by soil saprobic microfungi Veronika R eza´ c ova´ a,b,Ã, Hana Hrs elova´ a , Hana Gryndlerova in their solutions and in sterile soil by microfungal species and two well-known HA degraders were studied

  5. Biology is the study of life. Biologists analyze how systems function in organisms at the cellular and molecular levels

    E-Print Network [OSTI]

    Saldin, Dilano

    Biology is the study of life. Biologists analyze how systems function in organisms at the cellular and public sectors. People with degrees in biology are needed in areas as diverse as farming, food processing, and the environment, as well as in the biomedical and biotechnology fields. A degree in biology can also be used

  6. INFLUENCE OF NATURAL AND SYNTHETIC ORGANIC LIGANDS ON THE STABILITY AND MOBILITY OF REDUCED TC(IV)

    SciTech Connect (OSTI)

    Nathalie A. Wall; Baohua Gu

    2012-12-20

    The primary objectives were (1) to quantify the interactions of organic ligands with Tc(IV) through the generation of thermodynamic (complexation) and kinetic parameters needed to assess and predict the mobility of reduced Tc(IV) at DOE contaminated sites; and (2) to determine the impact of organic ligands on the mobility and fate of reduced Tc(IV) under field geochemical conditions.

  7. WHAT IS COMPOST? Composting refers to the biological decomposition and stabilization of organic materials by microorganisms under

    E-Print Network [OSTI]

    Mukhtar, Saqib

    WHAT IS COMPOST? Composting refers to the biological decomposition and stabilization of organic materials by microorganisms under aerobic (in the presence of oxygen) conditions. During the composting, good quality compost is produced that is biologically stable, relatively uniform in appearance, free

  8. Cellular delivery and site-specific targeting of organic fluorophores for super-resolution imaging in living cells

    E-Print Network [OSTI]

    Uttamapinant, Chayasith

    2013-01-01

    Recent advances in super-resolution fluorescence microscopy have pushed the spatial resolution of biological imaging down to a few nanometers. The key element to the development of such imaging modality is synthetic organic ...

  9. Biology

    E-Print Network [OSTI]

    Bailey, Charlotte M

    Nightty Enrichment} is a FREE tutoring program to neip students succeed in ?rst year. Biology science courses. CUSINE offers eyening tutoring right in your own ...

  10. Computers are from Mars, Organisms are from Venus: Interrelationship guide to Biology and Computer Science

    E-Print Network [OSTI]

    Kim, Junhyong

    . In recent years one active area of interdisciplinary merger has been biology and computer science. The noise youthful sciences? There is a kind of a natural affinity between biology and computer science. E is to "get over the mythical idea of an expert." Biology meets Computer Science: Computational Biology

  11. Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room News PublicationsAudits & InspectionsBeryllium andSamplerBiological Imaging byU.S.

  12. Synthetic analogs of bacterial quorum sensors

    DOE Patents [OSTI]

    Iyer, Rashi S.; Ganguly, Kumkum; Silks, Louis A.

    2013-01-08

    Bacterial quorum-sensing molecule analogs having the following structures: ##STR00001## and methods of reducing bacterial pathogenicity, comprising providing a biological system comprising pathogenic bacteria which produce natural quorum-sensing molecule; providing a synthetic bacterial quorum-sensing molecule having the above structures and introducing the synthetic quorum-sensing molecule into the biological system comprising pathogenic bacteria. Further is provided a method of targeted delivery of an antibiotic, comprising providing a synthetic quorum-sensing molecule; chemically linking the synthetic quorum-sensing molecule to an antibiotic to produce a quorum-sensing molecule-antibiotic conjugate; and introducing the conjugate into a biological system comprising pathogenic bacteria susceptible to the antibiotic.

  13. Synthetic analogs of bacterial quorum sensors

    DOE Patents [OSTI]

    Iyer, Rashi (Los Alamos, NM); Ganguly, Kumkum (Los Alamos, NM); Silks, Louis A. (Los Alamos, NM)

    2011-12-06

    Bacterial quorum-sensing molecule analogs having the following structures: ##STR00001## and methods of reducing bacterial pathogenicity, comprising providing a biological system comprising pathogenic bacteria which produce natural quorum-sensing molecule; providing a synthetic bacterial quorum-sensing molecule having the above structures and introducing the synthetic quorum-sensing molecule into the biological system comprising pathogenic bacteria. Further is provided a method of targeted delivery of an antibiotic, comprising providing a synthetic quorum-sensing molecule; chemically linking the synthetic quorum-sensing molecule to an antibiotic to produce a quorum-sensing molecule-antibiotic conjugate; and introducing the conjugate into a biological system comprising pathogenic bacteria susceptible to the antibiotic.

  14. DEFG0202ER63445, PI = Professor George M. Church June 28, 2011 PROPOSAL FOR DEVELOPMENT OF ENHANCED INVIVO AND EXVIVO SYNTHETIC BIOLOGY METHODS

    E-Print Network [OSTI]

    Church, George M.

    _office@genetics.med.harvard.edu FOA Number: DEFOA0000412 DOE/OSP Office: BER Biological Systems Science DOE/OSP Manager Contact Independence Avenue, S.W. Washington, DC 208551290 DOE Grant Number: DEFG0202ER63445 SUBCONTRACTS Objectives The goal of our proposed DOE Genomic Sciences Center renewal is to develop and demonstrate new

  15. Bions: A Family of Biomimetic Mineralo-Organic Complexes Derived from Biological Fluids

    E-Print Network [OSTI]

    Wu, Cheng-Yeu

    Mineralo-organic nanoparticles form spontaneously in human body fluids when the concentrations of calcium and phosphate ions exceed saturation. We have shown previously that these mineralo-organic nanoparticles possess ...

  16. Organic Matter Composition, Recycling Susceptibility, and the Effectiveness of the Biological Pump – An Evaluation Using NMR Spectra of Marine Plankton

    SciTech Connect (OSTI)

    Paytan, Adina [UCSC] [UCSC

    2014-02-19

    Carbon (C) sequestration through fertilization of phytoplankton with micronutrients and enhancement of the absorption and retention of atmospheric C by ocean biota heavily depends on the efficiency of the “biological pump”. The long-term effectiveness of this strategy depends on a net transfer of C from the upper ocean-atmosphere system to the deep ocean where the C is removed from contact with the atmosphere for an extended period of time. This C removal can be equated to the amount of C fixation by phytoplankton minus the C cycling and regeneration in the euphotic zone. If the regeneration efficiency is increased, then despite increased C fixation, no net loss (sequestration) of C will result. A reduction in cycling efficiency in the euphotic zone, on the other hand, will increase the effectiveness of the “biological pump” and thus C sequestration. The degree of organic matter biodegradation and recycling depends on the “reactivity” of compounds synthesized by the biota, which in turn, is controlled by the structural characteristic of these compounds. There is considerable evidence that different phytoplankton taxa differ substantially in their biogeochemical characteristics and it is likely that the relative abundance of different compounds synthesized by these distinct taxa, and even within each group at different growth conditions, will differ too. This variability in biosynthesis and thus abundance of a wide range of organic compounds in the water column would lend itself to different susceptibility for biodegradation and regeneration. Knowledge of the distribution of various organic matter structural groups synthesized by distinct taxa, the dependence of the organic matter compound classes on different growth conditions (temperature, light, nutrients) and the selective susceptibility of these compound to regeneration is crucial for estimating the potential for rapid regeneration in the euphotic zone, and thus the effectiveness of the “biological pump”.

  17. Integrated Biological and Cultural Practices Can Reduce Crop Rotation Period of Organic Strawberries

    E-Print Network [OSTI]

    2014-01-01

    in hydro- ponically grown strawberry (Fragaria x ananassaI. Tolhurst. 2001. Organic strawberry production—Grower’sand soil sickness of strawberry (Fragaria x ananassa).

  18. Synthetic heparin-binding growth factor analogs

    DOE Patents [OSTI]

    Pena, Louis A.; Zamora, Paul; Lin, Xinhua; Glass, John D.

    2007-01-23

    The invention provides synthetic heparin-binding growth factor analogs having at least one peptide chain that binds a heparin-binding growth factor receptor, covalently bound to a hydrophobic linker, which is in turn covalently bound to a non-signaling peptide that includes a heparin-binding domain. The synthetic heparin-binding growth factor analogs are useful as soluble biologics or as surface coatings for medical devices.

  19. Adapting to contradiction : competing models of organization in the United States organic foods industry

    E-Print Network [OSTI]

    Haedicke, Michael Anthony

    2008-01-01

    synthetic ingredients or sewage sludge; bioengineering; orthe use of municipal sewage sludge as fertilizer on organic

  20. Chemical characterization of dissolved organic matter (DOM) in seawater : structure, cycling, and the role of biology

    E-Print Network [OSTI]

    Quan, Tracy M. (Tracy Michelle), 1977-

    2005-01-01

    The goal of this thesis is to investigate three different areas relating to the characterization of dissolved organic matter (DOM): further determination of the chemical compounds present in high molecular weight DOM ...

  1. BIOLOGY SEMINAR PROMOTION LECTURE

    E-Print Network [OSTI]

    Shlizerman, Eli

    BIOLOGY SEMINAR PROMOTION LECTURE 12:00 PM SEMINAR HITCHCOCK HALL 132 REFRESHMENTS SERVED IN FOYER, November 24, 2014 "Life is flux" Dr. Jennifer Nemhauser Associate Professor Department of Biology drawn from molecular genetics, genomics, physiology and synthetic biology to build new tools to study

  2. Development and Applications Of Photosensitive Device Systems To Studies Of Biological And Organic Materials

    SciTech Connect (OSTI)

    Gruner, Sol

    2012-01-20

    The primary focus of the grant is the development of new x-ray detectors for biological and materials work at synchrotron sources, especially Pixel Array Detectors (PADs), and the training of students via research applications to problems in biophysics and materials science using novel x-ray methods. This Final Progress Report provides a high-level overview of the most important accomplishments. These major areas of accomplishment include: (1) Development and application of x-ray Pixel Array Detectors; (2) Development and application of methods of high pressure x-ray crystallography as applied to proteins; (3) Studies on the synthesis and structure of novel mesophase materials derived from block co-polymers.

  3. Microwave-induced thermoacoustic tomography: reconstruction by synthetic aperture 

    E-Print Network [OSTI]

    Feng, Dazi

    2001-01-01

    We have applied the synthetic-aperture method to linear-scanning microwave-induced thermoacoustic tomography in biological tissues. A non-focused ultrasonic transducer was used to receive thermoacoustic signals, to which the delay-and-sum algorithm...

  4. A mutation in ?-tubulin alters microtubule dynamics and organization and is synthetically lethal with the kinesin-like protein Pkl1p

    E-Print Network [OSTI]

    Paluh, Janet L.; Nogales, Eva; Oakley, Berl R.; McDonald, Kent; Pidoux, Alison; Cande, W.Z.

    2000-04-01

    ., 1999). Human g-tubulin can replace the endogenous protein in fission yeast (Horio and Oakley, 1994), suggesting that key aspects of g-tubulin function are broadly conserved. Microtubule motors play important roles in spindle as- sembly and dynamics. A.... The following strains and plasmids were kind gifts: mad22 strain (h2 ade6-M210, leu1-32, ura4-D18, mad2::ura41) from Dr. Shelly Sazar (Verna and Marrs McLean Departments of Biochemistry and Cell Biology, Baylor College of Medicine, Houston, TX; He et al., 1997...

  5. Biochemical Process Improvements & Synthetic Biology Validation...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    strategic and performance goals to convert biomass sugars (and other carbohydrate and lignin derivatives) to hydrocarbon fuels, as described in recent reports: - Davis, R. et...

  6. Petri Nets for Systems and Synthetic Biology.

    E-Print Network [OSTI]

    Heiner, M.; Gilbert, D.R.; Donaldson, R.

    Heiner,M. Gilbert,D.R. Donaldson,R. In M Bernardo, P Degano, and G Zavattaro (Eds.): SFM 2008, Springer LNCS 5016, 2008. pp 215â??264 Springer

  7. Synthetic Biology for Tailored Enzyme Cocktails Presentation...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    the United States: Generalizable improvements to enzyme screening technology leads to lower biomass to sugar biochemical conversion costs GOAL STATEMENT NOVOZYMES PRESENTATION 26...

  8. Synthetic biology approach to cellulose degradation 

    E-Print Network [OSTI]

    Lakhundi, Sahreena Saleem

    2012-06-22

    Cellulose, the most abundant biopolymer on earth, is composed of ? – 1,4 – linked glucose units, which in turn form a highly ordered crystalline structure that is insoluble and recalcitrant to degradation. It is the ...

  9. Studies on the biology of the crisamicin-producing organism Micromonospora purpureochromogenes subsp. celinoensis

    SciTech Connect (OSTI)

    Pope, J.A. Jr.

    1985-01-01

    A Micromonospora isolate, RV-101, obtained from the Red V Coconut Company in the Philippines, produces a new complex of antibiotics, the crisamicins. Using standard taxonomic methods for the genus Micromonospora, including micromorphology, growth characteristics on select media, whole cell analysis of chemical composition, and carbohydrate utilization patterns, the organism was classified as Micromonospora purpureochromogenes subsp. celinoensis. The chief character used in this classification was the production of a dark-brown diffusible pigment on media containing complex sources of nitrogen. The biosynthesis of crisamicin A was investigated by the technique of /sup 13/C acetate feeding and /sup 13/C NMR spectroscopy. Crisamicin A was found to be synthesized from acetate via the polyketide biosynthetic pathway. In addition, the assignment of one of two possible structures, differing in the position of phenolic hydroxyl groups, and in the point of linkage between the two monomers of the molecule, was made using the labeling data. The structure determined demonstrates that crisamicin A is unique among the benzoisochromanequinone antibiotics, in that it lacks an oxygen atom at position C-8.

  10. Synthetic heparin-binding factor analogs

    DOE Patents [OSTI]

    Pena, Louis A. (Poquott, NY); Zamora, Paul O. (Gaithersburg, MD); Lin, Xinhua (Plainview, NY); Glass, John D. (Shoreham, NY)

    2010-04-20

    The invention provides synthetic heparin-binding growth factor analogs having at least one peptide chain, and preferably two peptide chains branched from a dipeptide branch moiety composed of two trifunctional amino acid residues, which peptide chain or chains bind a heparin-binding growth factor receptor and are covalently bound to a non-signaling peptide that includes a heparin-binding domain, preferably by a linker, which may be a hydrophobic linker. The synthetic heparin-binding growth factor analogs are useful as pharmaceutical agents, soluble biologics or as surface coatings for medical devices.

  11. Synthetic guide star generation

    DOE Patents [OSTI]

    Payne, Stephen A. (Castro Valley, CA) [Castro Valley, CA; Page, Ralph H. (Castro Valley, CA) [Castro Valley, CA; Ebbers, Christopher A. (Livermore, CA) [Livermore, CA; Beach, Raymond J. (Livermore, CA) [Livermore, CA

    2008-06-10

    A system for assisting in observing a celestial object and providing synthetic guide star generation. A lasing system provides radiation at a frequency at or near 938 nm and radiation at a frequency at or near 1583 nm. The lasing system includes a fiber laser operating between 880 nm and 960 nm and a fiber laser operating between 1524 nm and 1650 nm. A frequency-conversion system mixes the radiation and generates light at a frequency at or near 589 nm. A system directs the light at a frequency at or near 589 nm toward the celestial object and provides synthetic guide star generation.

  12. Synthetic guide star generation

    SciTech Connect (OSTI)

    Payne, Stephen A.; Page, Ralph H.; Ebbers, Christopher A.; Beach, Raymond J.

    2004-03-09

    A system for assisting in observing a celestial object and providing synthetic guide star generation. A lasing system provides radiation at a frequency at or near 938 nm and radiation at a frequency at or near 1583 nm. The lasing system includes a fiber laser operating between 880 nm and 960 nm and a fiber laser operating between 1524 nm and 1650 nm. A frequency-conversion system mixes the radiation and generates light at a frequency at or near 589 nm. A system directs the light at a frequency at or near 589 nm toward the celestial object and provides synthetic guide star generation.

  13. Modules M.Sc. Biochemistry and Molecular Biology Title of the module Cell physiology of marine organisms: cellular energy budget

    E-Print Network [OSTI]

    Diekmann, Martin

    Cell physiology of marine organisms: cellular energy budget and metabolic fingerprinting Term of environmental factors such as temperature on cell metabolism of marine ectothermal organisms - Conceptual Deepening the knowledge of cell physiology of marine ectotherms. Topics will be: - Environmental impact

  14. Minor in Marine Biology Minor in Marine Biology

    E-Print Network [OSTI]

    Chen, Tsuhan

    Minor in Marine Biology Minor in Marine Biology General Goals of the Minor in Marine Biology About who choose the Minor in Marine Biology will learn about the biology, evolution and ecology of organisms that inhabit these environments and the ecological processes linking them. Marine biology draws

  15. Biodegradable synthetic bone composites

    DOE Patents [OSTI]

    Liu, Gao; Zhao, Dacheng; Saiz, Eduardo; Tomsia, Antoni P.

    2013-01-01

    The invention provides for a biodegradable synthetic bone composition comprising a biodegradable hydrogel polymer scaffold comprising a plurality of hydrolytically unstable linkages, and an inorganic component; such as a biodegradable poly(hydroxyethylmethacrylate)/hydroxyapatite (pHEMA/HA) hydrogel composite possessing mineral content approximately that of human bone.

  16. Synthetic and Mechanistic Chemistry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorking With LivermoreSustainable Land LabEnergyNationalScience BeatSynthetic

  17. Dual chain synthetic heparin-binding growth factor analogs

    DOE Patents [OSTI]

    Zamora, Paul O. (Gaithersburg, MD); Pena, Louis A. (Poquott, NY); Lin, Xinhua (Plainview, NY)

    2012-04-24

    The invention provides synthetic heparin-binding growth factor analogs having two peptide chains each branched from a branch moiety, such as trifunctional amino acid residues, the branch moieties separated by a first linker of from 3 to about 20 backbone atoms, which peptide chains bind a heparin-binding growth factor receptor and are covalently bound to a non-signaling peptide that includes a heparin-binding domain, preferably by a second linker, which may be a hydrophobic second linker. The synthetic heparin-binding growth factor analogs are useful as pharmaceutical agents, soluble biologics or as surface coatings for medical devices.

  18. Dual chain synthetic heparin-binding growth factor analogs

    DOE Patents [OSTI]

    Zamora, Paul O. (Gaithersburg, MD); Pena, Louis A. (Poquott, NY); Lin, Xinhua (Plainview, NY)

    2009-10-06

    The invention provides synthetic heparin-binding growth factor analogs having two peptide chains each branched from a branch moiety, such as trifunctional amino acid residues, the branch moieties separated by a first linker of from 3 to about 20 backbone atoms, which peptide chains bind a heparin-binding growth factor receptor and are covalently bound to a non-signaling peptide that includes a heparin-binding domain, preferably by a second linker, which may be a hydrophobic second linker. The synthetic heparin-binding growth factor analogs are useful as pharmaceutical agents, soluble biologics or as surface coatings for medical devices.

  19. Marine Biology

    E-Print Network [OSTI]

    Zaffino, Kyle

    2013-01-01

    this  door. ”   Marine  Biology   I  joined  the  military  RIVERSIDE   Marine  Biology   A Thesis submitted in partialBiology                                                                                                                        

  20. SYNTHETIC SLING FAILURE - EVALUATIONS & RECOMMENDATIONS

    SciTech Connect (OSTI)

    MACKEY TC; HENDERSON CS

    2009-10-26

    The information and evaluations provided in this report were compiled to address the recurring problem of synthetic sling failure. As safety is the number one priority in all work aspects, a solution must be devised to prevent accidents from occurring. A total of thirteen cases regarding synthetic sling failure were evaluated in order to determine their causes, effects, and preventative measures. From the collected data, it was found that all cases in which the synthetic sling contacted the edge of its load resulted in sling failure. It is required that adequate synthetic sling protection devices be used to protect slings in any lift where the sling comes in direct contact with the edge or corner of its load. However, there are no consensus codes or standards stating the type, material, or purpose of the type of protective device used to protect the sling from being cut. Numerous industry standards and codes provide vague descriptions on how to protect synthetic slings. Without a clear, concise statement of how to protect synthetic slings, it is common for inadequate materials and sling protection devices to be used in an attempt to meet the intent of these requirements. The use of an inadequate sling protection device is the main cause of synthetic sling failure in all researched cases. Commercial sling protection devices come in many shapes and sizes, and have a variety of names, as well as advertised uses. 'Abrasion pads' and 'wear protectors' are two different names for products with the same intended purpose. There is no distinguishable way to determine the extent of sling protection which these devices will provide, or what specific scenarios they are made for. This creates room for error in a field where error is unacceptable. This report provides a recommended action for hoisting and rigging activities which require synthetic slings to contact a load, as well as recommended changes to industry standards which will benefit overall industry safety.

  1. Model for biological communication in a nanofabricated cell-mimic driven by stochastic resonance

    SciTech Connect (OSTI)

    Karig, David K [ORNL; Siuti, Piro [ORNL; Dar, Roy D. [University of Tennessee, Knoxville (UTK); Retterer, Scott T [ORNL; Doktycz, Mitchel John [ORNL; Simpson, Michael L [ORNL

    2011-01-01

    Cells offer natural examples of highly efficient networks of nanomachines. Accordingly, both intracellular and intercellular communication mechanisms in nature are looked to as a source of inspiration and instruction for engineered nanocommunication. Harnessing biological functionality in this manner requires an interdisciplinary approach that integrates systems biology, synthetic biology, and nanofabrication. Recent years have seen the amassing of a tremendous wealth of data from the sequencing of new organisms and from high throughput expression experiments. At the same time, a deeper fundamental understanding of individual cell function has been developed, as exemplified by the growth of fields such as noise biology, which seeks to characterize the role of noise in gene expression. The availability of well characterized biological components coupled with a deeper understanding of cell function has led to efforts to engineer both living cells and to create bio-like functionality in non-living substrates in the field of synthetic biology. Here, we present a model system that exemplifies the synergism between these realms of research. We propose a synthetic gene network for operation in a nanofabricated cell mimic array that propagates a biomolecular signal over long distances using the phenomenon of stochastic resonance. Our system consists of a bacterial quorum sensing signal molecule, a bistable genetic switch triggered by this signal, and an array of nanofabricated cell mimic wells that contain the genetic system. An optimal level of noise in the system helps to propagate a time-varying AHL signal over long distances through the array of mimics. This noise level is determined both by the system volume and by the parameters of the genetic network. Our proposed genetically driven stochastic resonance system serves as a testbed for exploring the potential harnessing of gene expression noise to aid in the transmission of a time-varying molecular signal.

  2. Future Prospects of Synthetic Fuels 

    E-Print Network [OSTI]

    Fryback, M. G.

    1982-01-01

    It is important for the future of this nation to reach the goal of demonstrated definition and quantification of the parameters which influence the ability to use this country's vast resources of coal and oil shale for production of synthetic fuels...

  3. Synthetic substrates for enzyme analysis

    DOE Patents [OSTI]

    Bissell, Eugene R. (Alamo, CA); Mitchell, Alexander R. (Livermore, CA); Pearson, Karen W. (Livermore, CA); Smith, Robert E. (Livermore, CA)

    1983-01-01

    Synthetic substrates are provided which may be represented as A-D. The A moiety thereof includes an amino acid, polypeptide, or derivative thereof. The D moiety thereof includes 7-amino coumarin derivatives having an electron withdrawing substituent group at the 3 position carbon or fused between the 3 and 4 position carbons.

  4. Synthetic substrates for enzyme analysis

    DOE Patents [OSTI]

    Bissell, E.R.; Mitchell, A.R.; Pearson, K.W.; Smith, R.E.

    1983-06-14

    Synthetic substrates are provided which may be represented as A-D. The A moiety includes an amino acid, polypeptide, or derivative. The D moiety includes 7-amino coumarin derivatives having an electron withdrawing substituent group at the 3 position carbon or fused between the 3 and 4 position carbons. No Drawings

  5. Tools, strategies, and applications of synthetic biology in Saccharomyces cerevisiae

    E-Print Network [OSTI]

    Lee, Michael Eun-Suk

    2015-01-01

    Pichia stipitis to improve bioethanol production. ACS Chem.Sawayama, S. Efficient bioethanol production from xylose byA. et al. Efficient bioethanol production by a recombinant

  6. SCIENCE AT THE CROSSROADS Synthetic Biology: Life as App Store

    E-Print Network [OSTI]

    Newman, Stuart A.

    the formulation of a science of inheritance. Bronze and Iron Age metallurgy flourished without the atomic theory

  7. Combating biofilms and antibiotic resistance using synthetic biology

    E-Print Network [OSTI]

    Lu, Timothy K. (Timothy Kuan-Ta), 1981-

    2008-01-01

    Bacterial infections represent a significant source of morbidity and mortality. Biofilms and antibiotic resistance pose challenges to our future ability to treat bacterial diseases with antibiotics (1). Bacteria frequently ...

  8. Synthetic Metabolism: Engineering Biology at the Protein and Pathway Scales

    E-Print Network [OSTI]

    Martin, Collin H.

    Biocatalysis has become a powerful tool for the synthesis of high-value compounds, particularly so in the case of highly functionalized and/or stereoactive products. Nature has supplied thousands of enzymes and assembled ...

  9. Tools, strategies, and applications of synthetic biology in Saccharomyces cerevisiae

    E-Print Network [OSTI]

    Lee, Michael Eun-Suk

    2015-01-01

    and twice with 100mM Lithium Acetate (Sigma). Cells wereScientific), 360µL of 1M Lithium Acetate, 250µL of salmonfollowed standard Lithium acetate transformation protocol 57

  10. Bromotyrosine-derived natural products: synthetic and biological studies

    E-Print Network [OSTI]

    Shearman, James

    2011-07-12

    liquid chromatography-mass spectrometry LDA lithium diisopropylamide Lit literature LogP logarithm of the partition coefficient LRI London Research Institute m meta m metre or multiplet (NMR) or medium (IR) M molar or mitotic m/z mass... in red algae and sponges and in terms of structure, range from one-carbon species, such as iodomethane and carbon tetrabromide,8 to much more complex substances, for example thyrsiferyl acetate (1) (Figure 1).9 Interestingly, the first halogenated...

  11. Synthetic Biology and reshaping plant form Jim Haseloff

    E-Print Network [OSTI]

    Rosso, Lula

    Industrial Revolution: based on innovations in coal, iron, steam and mechanical engineering #12; Steam power machines.This enabled rapid development of e cient semi-automated factories Iron founding - Coke replaced

  12. Reprogramming alkaloid biosynthesis in Catharanthus roseus : synthetic biology in plants

    E-Print Network [OSTI]

    Runguphan, Weerawat

    2011-01-01

    The medicinal plant Madagascar periwinkle (Catharanthus roseus) produces over 130 monoterpene indole alkaloid (MIA) natural products. Many of these compounds have pharmaceutical value, such as the anticancer agents vinblastine ...

  13. Synthetic Biology Offers New Hope For Malaria Victims

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorking With LivermoreSustainable Land LabEnergyNationalScience Beat Magazine

  14. Copy of Synthetic Biology of Novel Thermophilic Bacteria for Enhanced

    Office of Scientific and Technical Information (OSTI)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefieldSulfate Reducing BacteriaConnect Collider Testspolycarbonate and

  15. Synthetic Biology of Novel Thermophilic Bacteria for Enhanced Production of

    Office of Scientific and Technical Information (OSTI)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefieldSulfateSciTechtail. (Conference)Feedback System inStatusandArticle)

  16. Comparative Microbial Genomics group CenterforBiologicalSequenceAnalysisTheTechnicalUniversityofDenmarkDTU

    E-Print Network [OSTI]

    Ussery, David W.

    Comparative Microbial Genomics group CenterforBiologicalSequenceAnalysisTheTechnicalUniversityofDenmarkDTU Minimal genomes in bacterial Genera Dave Ussery European Conference on Synthetic Biology: Design 2007 #12;Comparative Microbial Genomics group Centerfor

  17. Objective methods for evaluating synthetic intonation. 

    E-Print Network [OSTI]

    Clark, Robert A J; Dusterhoff, Kurt E

    1999-01-01

    This paper describes the development and evaluation of objective methods for testing synthetic intonation. While subjective methods are available for assessing the quality of synthetic intonation, such tests consume ...

  18. Synthetic LDL as targeted drug delivery vehicle

    DOE Patents [OSTI]

    Forte, Trudy M. (Berkeley, CA); Nikanjam, Mina (Richmond, CA)

    2012-08-28

    The present invention provides a synthetic LDL nanoparticle comprising a lipid moiety and a synthetic chimeric peptide so as to be capable of binding the LDL receptor. The synthetic LDL nanoparticle of the present invention is capable of incorporating and targeting therapeutics to cells expressing the LDL receptor for diseases associated with the expression of the LDL receptor such as central nervous system diseases. The invention further provides methods of using such synthetic LDL nanoparticles.

  19. 7th Annual Systems Biology Symposium: Systems Biology and Engineering

    SciTech Connect (OSTI)

    Galitski, Timothy P.

    2008-04-01

    Systems biology recognizes the complex multi-scale organization of biological systems, from molecules to ecosystems. The International Symposium on Systems Biology has been hosted by the Institute for Systems Biology in Seattle, Washington, since 2002. The annual two-day event gathers the most influential researchers transforming biology into an integrative discipline investingating complex systems. Engineering and application of new technology is a central element of systems biology. Genome-scale, or very small-scale, biological questions drive the enigneering of new technologies, which enable new modes of experimentation and computational analysis, leading to new biological insights and questions. Concepts and analytical methods in engineering are now finding direct applications in biology. Therefore, the 2008 Symposium, funded in partnership with the Department of Energy, featured global leaders in "Systems Biology and Engineering."

  20. Synthetic thermoelectric materials comprising phononic crystals

    DOE Patents [OSTI]

    El-Kady, Ihab F; Olsson, Roy H; Hopkins, Patrick; Reinke, Charles; Kim, Bongsang

    2013-08-13

    Synthetic thermoelectric materials comprising phononic crystals can simultaneously have a large Seebeck coefficient, high electrical conductivity, and low thermal conductivity. Such synthetic thermoelectric materials can enable improved thermoelectric devices, such as thermoelectric generators and coolers, with improved performance. Such synthetic thermoelectric materials and devices can be fabricated using techniques that are compatible with standard microelectronics.

  1. Chemistry & Biology Natural and Nonnatural Vitamin Ds Compared

    E-Print Network [OSTI]

    Chemistry & Biology 1266 Natural and Nonnatural Vitamin Ds Compared with the Protein-Bound Vitamin Structures of the active vitamin D metabolite 1,25(OH)2D3 (A), the related synthetic agonist LG190155 (B

  2. Environmental data energy technology characterizations: synthetic fuels

    SciTech Connect (OSTI)

    Not Available

    1980-04-01

    Environmental Data Energy Technology Characterizations are publications which are intended to provide policy analysts and technical analysts with basic environmental data associated with key energy technologies. This publication provides documentation on synthetic fuels (coal-derived and oil shale). The transformation of the energy in coal and oil shale into a more useful form is described in this publication in terms of major activity areas in the synthetic fuel cycles, that is, in terms of activities which produce either an energy product or a fuel leading to the production of an energy product in a different form. The activities discussed in this document are coal liquefaction, coal gasification, in-situ gasification, and oil shales. These activities represent both well-documented and advanced activity areas. The former activities are characterized in terms of actual operating data with allowance for future modification where appropriate. Emissions are assumed to conform to environmental standards. The advanced activity areas examined are those like coal liquefaction and in-situ retorting of oil shale. For these areas, data from pilot or demonstration plants were used where available; otherwise, engineering studies provided the data. The organization of the chapters in this volume is designed to support the tabular presentation in the summary volume. Each chapter begins with a brief description of the activity under consideration. The standard characteristics, size, availability, mode of functioning and place in the fuel cycle are presented. Next, major legislative and/or technological factors influencing the commercial operation of the activity are offered. Discussions of resources consumed, residuals produced, and economics follow. To aid in comparing and linking the different activity areas, data for each area are normalized to 10/sup 12/ Btu of energy output from the activity.

  3. Synthetic Genomics: Options for Governance

    E-Print Network [OSTI]

    Garfinkel, Michele

    2007-10-17

    Gene and genome synthesis, that is, constructing long stretches of DNA from constituent chemicals, provides scientists with new and unparalleled capabilities both for understanding biology and for using it for beneficial ...

  4. Synthetic carbonaceous fuels and feedstocks

    DOE Patents [OSTI]

    Steinberg, Meyer (Huntington Station, NY)

    1980-01-01

    This invention relates to the use of a three compartment electrolytic cell in the production of synthetic carbonaceous fuels and chemical feedstocks such as gasoline, methane and methanol by electrolyzing an aqueous sodium carbonate/bicarbonate solution, obtained from scrubbing atmospheric carbon dioxide with an aqueous sodium hydroxide solution, whereby the hydrogen generated at the cathode and the carbon dioxide liberated in the center compartment are combined thermocatalytically into methanol and gasoline blends. The oxygen generated at the anode is preferably vented into the atmosphere, and the regenerated sodium hydroxide produced at the cathode is reused for scrubbing the CO.sub.2 from the atmosphere.

  5. Method of producing synthetic pitch

    DOE Patents [OSTI]

    Kennel, Elliot B. (Morgantown, WV); Stansberry, Peter G. (North Olmsted, OH); Stiller, Alfred H. (Morgantown, WV); Zondlo, John W. (Albright, WV)

    2012-07-24

    Embodiments of a method are described for modifying pitches, oils, tars, and binders by using these materials as solvents to extract organic chemicals from coal.

  6. Entraining synthetic genetic oscillators Alexandre Wagemakers,1

    E-Print Network [OSTI]

    Rey Juan Carlos, Universidad

    Entraining synthetic genetic oscillators Alexandre Wagemakers,1 Javier M. Buldú,2 Miguel A. F genetic oscillators, which consists in the entrainment of a colony of repressilators by external

  7. Survey and Control of Synthetic Organics in Texas Water Supplies 

    E-Print Network [OSTI]

    Batchelor, B.; Shannon, J. D.; Yang, P.

    1981-01-01

    Four Texas water supplies (Lake Somerville, Lake Livingston, Neches River, and Sabine River) were surveyed to determine their tendency to form trihalomethanes when chlorinated. The ability of conventional and innovative treatment processes to reduce...

  8. New Design and Synthetic Strategies of Metal-Organic Frameworks 

    E-Print Network [OSTI]

    Wei, Zhangwen

    2014-04-18

    groups.102 In addition to normal UMCs, spillover mainly based on platinum and palladium has been studied, which will break the H-H bonding to form single atoms attached to the framework.103 In addition, introducing different neutral functional groups...

  9. Synthetic Strategies to Colloidal Nanocrystals

    E-Print Network [OSTI]

    Sandini, Giulio

    and relative concentration of molecular precursors; catalysts; organic stabilizers; growth temperature #12 environment, depending on the particle size and on a variety of surface effects. NANOCRYSTALS: Single domain electron micrograph of ~30nm zinc oxide #12;TiO2 Nanorods 10 nm #12;#12;Surfactants are amphiphilic

  10. Navigation Links Biology News

    E-Print Network [OSTI]

    Espinosa, Horacio D.

    Navigation Links Biology News Medicine News Biology Products Medicine Products Biology Definition Medicine Definition Biology Technology Medicine Technology Biology Dictionary Medicine Dictionary Biology Navigation Medical Navigation MHOME >> BIOLOGY >> NEWS Single-cell transfection tool enables added control

  11. Synthetic CO.sub.2 acceptor

    DOE Patents [OSTI]

    Lancet, Michael S. (Pittsburgh, PA); Curran, George P. (Pittsburgh, PA)

    1981-08-18

    A synthetic CO.sub.2 acceptor consisting essentially of at least one compound selected from the group consisting of calcium oxide and calcium carbonate supported in a refractory carrier matrix, the carrier having the general formula Ca.sub.5 (SiO.sub.4).sub.2 CO.sub.3. A method for producing the synthetic CO.sub.2 acceptor is also disclosed.

  12. Flow control via synthetic jet actuation 

    E-Print Network [OSTI]

    Miller, Adam Cole

    2005-02-17

    -1 FLOW CONTROL VIA SYNTHETIC JET ACTUATION A Thesis by ADAM COLE MILLER Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE December... 2004 Major Subject: Aerospace Engineering FLOW CONTROL VIA SYNTHETIC JET ACTUATION A Thesis by ADAM COLE MILLER Submitted to Texas A&M University in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE...

  13. Biological Safety

    Broader source: Energy.gov [DOE]

    The DOE's Biological Safety Program provides a forum for the exchange of best practices, lessons learned, and guidance in the area of biological safety. This content is supported by the Biosurety Executive Team. The Biosurety Executive Team is a DOE-chartered group. The DOE Office of Worker Safety and Health Policy provides administrative support for this group. The group identifies biological safety-related issues of concern to the DOE and pursues solutions to issues identified.

  14. Synthetic Self-Healing Methods

    SciTech Connect (OSTI)

    Bello, Mollie [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-06-02

    Given enough time, pressure, temperature fluctuation, and stress any material will fail. Currently, synthesized materials make up a large part of our everyday lives, and are used in a number of important applications such as; space travel, under water devices, precise instrumentation, transportation, and infrastructure. Structural failure of these material scan lead to expensive and dangerous consequences. In an attempt to prolong the life spans of specific materials and reduce efforts put into repairing them, biologically inspired, self-healing systems have been extensively investigated. The current review explores recent advances in three methods of synthesized self-healing: capsule based, vascular, and intrinsic. Ideally, self-healing materials require no human intervention to promote healing, are capable of surviving all the steps of polymer processing, and heal the same location repeatedly. Only the vascular method holds up to all of these idealities.

  15. Quantum Biology

    E-Print Network [OSTI]

    Alessandro Sergi

    2009-07-11

    A critical assessment of the recent developments of molecular biology is presented. The thesis that they do not lead to a conceptual understanding of life and biological systems is defended. Maturana and Varela's concept of autopoiesis is briefly sketched and its logical circularity avoided by postulating the existence of underlying {\\it living processes}, entailing amplification from the microscopic to the macroscopic scale, with increasing complexity in the passage from one scale to the other. Following such a line of thought, the currently accepted model of condensed matter, which is based on electrostatics and short-ranged forces, is criticized. It is suggested that the correct interpretation of quantum dispersion forces (van der Waals, hydrogen bonding, and so on) as quantum coherence effects hints at the necessity of including long-ranged forces (or mechanisms for them) in condensed matter theories of biological processes. Some quantum effects in biology are reviewed and quantum mechanics is acknowledged as conceptually important to biology since without it most (if not all) of the biological structures and signalling processes would not even exist. Moreover, it is suggested that long-range quantum coherent dynamics, including electron polarization, may be invoked to explain signal amplification process in biological systems in general.

  16. National Laboratory] Basic Biological Sciences(59) Biological...

    Office of Scientific and Technical Information (OSTI)

    Achievements of structural genomics Terwilliger, Thomas C. Los Alamos National Laboratory Basic Biological Sciences(59) Biological Science Biological Science Abstract Not...

  17. Insect Controls for Organic Gardeners. 

    E-Print Network [OSTI]

    Lewis, Kenneth R.; Turney, H.A.

    1979-01-01

    ................................................................... 9 Acknowledgments ...................................................... 10 References ............................................................. 10 INSECT CONTROLS FOR ORGANIC GARDENERS Kenneth R. Lewis and H. A. Turney* Interest in organic... gardening has increased in recent years. Organic gardening means enriching the garden soil with natural products (mulches, composts and animal manures) and controlling insects, diseases and weeds with cultural, mechanical and biological methods rather...

  18. Immobilization of radioiodine in synthetic boracite

    DOE Patents [OSTI]

    Babad, H.; Strachan, D.M.

    1982-09-23

    A nuclear waste storage product is disclosed in which radioiodine is incorporated in a synthetic boracite. The boracite may be prepared by reacting a transition metal iodide with an alkali horate under mild hydrothermal conditions, drying the reaction product, and then hot pressing.

  19. Coal based synthetic fuel technology assessment guides

    SciTech Connect (OSTI)

    Not Available

    1981-09-01

    Seventeen synthetic fuel processes are described in detail and compared on a uniform basis. This work was supported by the Energy Information Administration for the purpose of technology assessment of the processes, their efficiency, the capitalized and operating cost of plants of similar size, possible constraints, possible siting problems, regional effects, pollution control, etc. (LTN)

  20. Cellular CSK resembles natural and synthetic materials

    E-Print Network [OSTI]

    Sniadecki, Nathan J.

    Theory Pinned-pinned, three-point bending Es is modulus of elasticity for beam (F-actin GPa) d 3 48 s F l E ISession 15 #12;2 Cellular CSK resembles natural and synthetic materials Felt Paper Cotton NASA r r #12;6 (a/k/a Second Moment of Area) Geometric resistance of a beam to bending 2 2

  1. CO2 Capture with Enzyme Synthetic Analogue

    SciTech Connect (OSTI)

    Harry Cordatos

    2010-11-08

    Overview of an ongoing, 2 year research project partially funded by APRA-E to create a novel, synthetic analogue of carbonic anhydrase and incorporate it into a membrane for removal of CO2 from flue gas in coal power plants. Mechanism background, preliminary feasibility study results, molecular modeling of analogue-CO2 interaction, and program timeline are provided.

  2. 2010 Tetrapyrroles, Chemistry & Biology of Gordon Research Conference

    SciTech Connect (OSTI)

    Angela Wilks

    2010-07-30

    The objective of the Chemistry & Biology of Tetrapyrroles Gordon Conference is to bring together researchers from diverse disciplines that otherwise would not interact. By bringing biologists, chemists, engineers and clinicians with a common interest in tetrapyrroles the conference provides a forum for cross-disciplinary ideas and collaboration. The perspective provided by biologists, chemists, and clinicians working in fields such as newly discovered defects in human porphyrin metabolism, the myriad of strategies for light harvesting in photosynthetic organisms, novel tetrapyrroles that serve as auxiliary chromophores or enzyme cofactors, synthetic strategies in the design of novel tetrapyrrole scaffolds, and tetrapyrrole based cell signaling and regulatory systems, makes this conference unique in the field. Over the years the growing evidence for the role of tetrapyrroles and their reactive intermediates in cell signaling and regulation has been of increasing importance at this conference. The 2010 conference on Chemistry & Biology of Tetrapyrroles will focus on many of these new frontiers as outlined in the preliminary program listed. Speakers will emphasize unpublished results and new findings in the field. The oral sessions will be followed by the highly interactive afternoon poster sessions. The poster sessions provide all conferees with the opportunity to present their latest research and to exchange ideas in a more informal setting. As in the past, this opportunity will continue during the nightly social gathering that takes place in the poster hall following the evening lectures. All conferees are encouraged to submit and present posters. At the conference the best poster in the areas of biology, chemistry and medicine will be selected by a panel of previous conference chairs.

  3. Biological preconcentrator

    DOE Patents [OSTI]

    Manginell, Ronald P. (Albuquerque, NM); Bunker, Bruce C. (Albuquerque, NM); Huber, Dale L. (Albuquerque, NM)

    2008-09-09

    A biological preconcentrator comprises a stimulus-responsive active film on a stimulus-producing microfabricated platform. The active film can comprise a thermally switchable polymer film that can be used to selectively absorb and desorb proteins from a protein mixture. The biological microfabricated platform can comprise a thin membrane suspended on a substrate with an integral resistive heater and/or thermoelectric cooler for thermal switching of the active polymer film disposed on the membrane. The active polymer film can comprise hydrogel-like polymers, such as poly(ethylene oxide) or poly(n-isopropylacrylamide), that are tethered to the membrane. The biological preconcentrator can be fabricated with semiconductor materials and technologies.

  4. MICROREVIEW Improving the Properties of Organic Dyes by Molecular Encapsulation

    E-Print Network [OSTI]

    Smith, Bradley D.

    ] Modern research on organic dyes includes in- vestigations of building blocks for conjugated polymers, hy-consuming synthetic processes. In- deed, molecular encapsulation is an effective way to recycle familiar dyes

  5. Biomimetics Engineering from Biology

    E-Print Network [OSTI]

    Agogino, Alice M.

    Biomimetics or Engineering from Biology Hari Dharan Department of Mechanical Engineering University" ­ copying only? !!"Biologically-Inspired Design" !!"Engineering from Biology" Definition !!It is not "biology for engineers". !!It is not "imitating" or "copying" biology. !!It is not "reverse

  6. Feedback control of flow separation using synthetic jets 

    E-Print Network [OSTI]

    Kim, Kihwan

    2006-04-12

    The primary goal of this research is to assess the effect of synthetic jets on flow separation and provide a feedback control strategy for flow separation using synthetic jets. The feedback control synthesis is conducted based upon CFD simulation...

  7. Active flow separation control using synthetic jet actuators 

    E-Print Network [OSTI]

    Rao, Preetham P

    2000-01-01

    The use of synthetic jet actuators for controlling the boundary layer flow and flow separation over a wing is investigated. A theory for the optimum design of actuators using motors is developed. A motor driven synthetic jet actuator is built...

  8. Axisymmetric Synthetic Jets: An Experimental and Theoretical Examination

    E-Print Network [OSTI]

    Mohseni, Kamran

    Axisymmetric Synthetic Jets: An Experimental and Theoretical Examination Gopi Krishnan and Kamran synthetic jet driven by a piezoelectric membrane issuing into a quiescent environment is studied in this paper. The self-similar behavior exhibited by both synthetic and continuous turbulent jets leads

  9. NMR Studies on Organic and Biological Solids

    E-Print Network [OSTI]

    Yang, Chen

    2015-01-01

    A. ; Baldus, M. Angew. Chemie - Int. Ed. 2010, 49, 8346.A. ; Baldus, M. Angew. Chemie - Int. Ed. 2010, 49, 8346. Ye,E. ; Pintacuda, G. Angew. Chemie (17) Paluch, P. ; Pawlak,

  10. Investigations of the Biological Roles of Substituted Cyclohexadienes 

    E-Print Network [OSTI]

    Bench, Bennie John

    2011-02-22

    . ....................................................................................... 133 Figure 52. 4-nitrocinnamaldehyde Schiff base formation. ....................................... 134? Figure 53. Time course analysis of proline-promoted formation of biphenyl-cinnamaldehyde heterodimers... the protein mediated reaction, we developed a synthetic procedure to produce a wide array of cycloterpenal by utilizing L-proline. Over 100 cycloterpenals were synthesized and screened for their biological activities against an array of cell based screens...

  11. Fe(III) Oxide Reactivity Toward Biological versus Chemical

    E-Print Network [OSTI]

    Roden, Eric E.

    size, surface area, and solubility of the mineral. Such variations lead to a continuum of Fe(III) oxideFe(III) Oxide Reactivity Toward Biological versus Chemical Reduction E R I C E . R O D E N of synthetic Fe(III) oxides with a broad range of crystallinity and specific surface area were examined

  12. Novel Aryne Chemistry in Organic Synthesis

    SciTech Connect (OSTI)

    Zhijian Liu

    2006-12-12

    Arynes are among the most intensively studied systems in chemistry. However, many aspects of the chemistry of these reactive intermediates are not well understood yet and their use as reagents in synthetic organic chemistry has been somewhat limited, due to the harsh conditions needed to generate arynes and the often uncontrolled reactivity exhibited by these species. Recently, o-silylaryl triflates, which can generate the corresponding arynes under very mild reaction conditions, have been found very useful in organic synthesis. This thesis describes several novel and useful methodologies by employing arynes, which generate from o-silylaryl triflates, in organic synthesis. An efficient, reliable method for the N-arylation of amines, sulfonamides and carbamates, and the O-arylation of phenols and carboxylic acids is described in Chapter 1. Amines, sulfonamides, phenols, and carboxylic acids are good nucleophiles, which can react with arynes generated from a-silylaryl triflates to afford the corresponding N- and O-arylated products in very high yields. The regioselectivity of unsymmetrical arynes has also been studied. A lot of useful, functional groups can tolerate our reaction conditions. Carbazoles and dibenzofurans are important heteroaromatic compounds, which have a variety of biological activities. A variety of substituted carbazoles and dibenzofwans are readily prepared in good to excellent yields starting with the corresponding o-iodoanilines or o-iodophenols and o-silylaryl triflates by a treatment with CsF, followed by a Pd-catalyzed cyclization, which overall provides a one-pot, two-step process. By using this methodology, the carbazole alkaloid mukonine has been concisely synthesized in a very good yield. Insertion of an aryne into a {sigma}-bond between a nucleophile and an electrophile (Nu-E) should potentially be a very beneficial process from the standpoint of organic synthesis. A variety of substituted ketones and sulfoxides have been synthesized in good yields via the intermolecular C-N {sigma}-bond addition of amides and S-N {sigma}-bond addition of sulfinamides to arynes under mild reaction conditions. The indazole moiety is a frequently found subunit in drug substances with important biological activities. Indazole analogues have been readily synthesized under mild reaction conditions by the [3+2] cycloaddition of a variety of diazo compounds with o-silylaryl triflates in the presence of CsF or TBAF. Polycyclic aromatic and heteroaromatic hydrocarbons have been synthesized in high yields by two different processes involving the Pd-catalyzed annulation of arynes. Both processes appear to involve the catalytic, stepwise coupling of two very reactive substrates, an aryne and an organopalladium species, to generate excellent yields of cross-coupled products.

  13. Cellular CSK resembles natural and synthetic materials

    E-Print Network [OSTI]

    Sniadecki, Nathan J.

    -pinned, three-point bending 7 Es is modulus of elasticity for beam (F-actin GPa) 3 48 s F l E I = #12;StressSession 15 #12;Cellular CSK resembles natural and synthetic materials Felt Paper Cotton 2 Cotton = #12;(a/k/a Second Moment of Area) Geometric resistance of a beam to bending 2 x A I y dA= y 6 2 4 4 4

  14. TCD-IISc Symposium "Chemistry & Chemical Biology"

    E-Print Network [OSTI]

    O'Mahony, Donal E.

    actinide chemistry, with a focus on coordination and organometallic uranium chemistry. Paula ColavitaTCD-IISc Symposium "Chemistry & Chemical Biology" Trinity College Clive Williams, Dean of Chemistry. Research areas include supramolecular organic and inorganic chemistry and medicinal chemistry

  15. DEPARTMENT OF BIOLOGY AND MARINE BIOLOGY

    E-Print Network [OSTI]

    Olszewski Jr., Edward A.

    DEPARTMENT OF BIOLOGY AND MARINE BIOLOGY GRADUATE PROGRAM REVIEW 2000-2007 #12;i TABLE OF CONTENTS ....................................................................... 389 #12;ii EXECUTIVE SUMMARY The Department of Biology and Marine Biology contributes importantly). The department began offering the Master of Science in Marine Biology in 1980, and the Master of Science

  16. DCC Case Study: Integrative Biology 

    E-Print Network [OSTI]

    Donnelly, Martin; Boyd, Victoria; Spellman, Jill

    2008-04-03

    these illnesses. The main aim of the Integrative Biology (IB) project is to realise this potential by developing multi-scale models - spanning the range from genes to whole organs - and to provide data management features for its disparate users including...

  17. Biological Control of Saltcedar 

    E-Print Network [OSTI]

    Knutson, Allen E.; DeLoach, C. Jack; Muegge, Mark A.

    2003-10-21

    stream_source_info pdf_1854.pdf.txt stream_content_type text/plain stream_size 8896 Content-Encoding ISO-8859-1 stream_name pdf_1854.pdf.txt Content-Type text/plain; charset=ISO-8859-1 A sustainable approach using insect... organisms to suppress saltcedar. This method is called biological control. To help control saltcedar, insects that feed only on the plant are being intro- duced into Texas and the western United States. S Invader of rivers, lakes and wetlands Saltcedar, also...

  18. Biology reflective assessment curriculum

    E-Print Network [OSTI]

    Bayley, Cheryl Ann

    2011-01-01

    Penick, J. E. (1998). Biology: A community context. Newof a standards-based high school biology curriculum.The American Biology Teacher Li, J. , Klahr, D. , & Siler,

  19. Biological Sciences http://www.clas.wayne.edu/biology/

    E-Print Network [OSTI]

    Finley Jr., Russell L.

    Biological Sciences http://www.clas.wayne.edu/biology/ Divisions: Evolutionary and Organismal Biology Molecular Biology and Biotechnology Cellular, Developmental, and Neurobiology #12;Biological Sciences http://www.clas.wayne.edu/biology/ · Cell Biology and Cytogenetics (Beningo, Tucker, Greenberg

  20. Engineering RNA logic with synthetic splicing ribozymes

    E-Print Network [OSTI]

    Che, Austin, 1979-

    2008-01-01

    Reusable components, such as logic gates and code libraries, simplify the design and implementation of electronic circuits and computer programs. The engineering of biological systems would benefit also from reusable ...

  1. Theory in Biology Computational

    E-Print Network [OSTI]

    Goldbeter, Albert

    Magazine R601 Theory in Biology Computational biology: A propagating wave of interest Albert Goldbeter Systems biology, computational biology, integrative biology... many names are being used and tendency to take a global view of problems in biology. This field is not entirely novel, but what is clear

  2. Nonlinear Elasticity in Biological Gels

    E-Print Network [OSTI]

    Cornelis Storm; Jennifer J. Pastore; Fred C. MacKintosh; Tom C. Lubensky; Paul A. Janmey

    2004-06-01

    Unlike most synthetic materials, biological materials often stiffen as they are deformed. This nonlinear elastic response, critical for the physiological function of some tissues, has been documented since at least the 19th century, but the molecular structure and the design principles responsible for it are unknown. Current models for this response require geometrically complex ordered structures unique to each material. In this Article we show that a much simpler molecular theory accounts for strain stiffening in a wide range of molecularly distinct biopolymer gels formed from purified cytoskeletal and extracellular proteins. This theory shows that systems of semi-flexible chains such as filamentous proteins arranged in an open crosslinked meshwork invariably stiffen at low strains without the need for a specific architecture or multiple elements with different intrinsic stiffnesses.

  3. Biology 3515/Chemistry 3515 Biological Chemistry Laboratory

    E-Print Network [OSTI]

    Simons, Jack

    Biology 3515/Chemistry 3515 Biological Chemistry Laboratory Spring 2013 (Draft Syllabus, 23 August 2012) Course Description and Objectives: This course is intended for students who have taken Biology and function, particularly for enzymes. Prerequisites: Biology 3510 or Chemistry 3510 Instructor: David P

  4. Chemistry in Motion: Tiny Synthetic Motors

    E-Print Network [OSTI]

    Peter H. Colberg; Shang Yik Reigh; Bryan Robertson; Raymond Kapral

    2014-11-03

    In this Account, we describe how synthetic motors that operate by self-diffusiophoresis make use of a self-generated concentration gradient to drive motor motion. A description of propulsion by self-diffusiophoresis is presented for Janus particle motors comprising catalytic and noncatalytic faces. The properties of the dynamics of chemically powered motors are illustrated by presenting the results of particle-based simulations of sphere-dimer motors constructed from linked catalytic and noncatalytic spheres. The geometries of both Janus and sphere-dimer motors with asymmetric catalytic activity support the formation of concentration gradients around the motors. Because directed motion can occur only when the system is not in equilibrium, the nature of the environment and the role it plays in motor dynamics are described. Rotational Brownian motion also acts to limit directed motion, and it has especially strong effects for very small motors. We address the following question: how small can motors be and still exhibit effects due to propulsion, even if only to enhance diffusion? Synthetic motors have the potential to transform the manner in which chemical dynamical processes are carried out for a wide range of applications.

  5. A model for improving microbial biofuel production using a synthetic...

    Office of Scientific and Technical Information (OSTI)

    loop Cells use feedback to implement a diverse range of regulatory functions. Building synthetic feedback control systems may yield insight into the roles that feedback can...

  6. Synthetic nanotubes lay foundation for new technology: Artificial...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Synthetic nanotubes lay foundation for new technology: Artificial pores mimic key features of natural pores By Tona Kunz * July 17, 2012 Tweet EmailPrint Scientists have overcome...

  7. Molecular Recognition by Synthetic Receptors in Biomimetic and Cellular Systems

    E-Print Network [OSTI]

    Ghang, Yoo-Jin

    2015-01-01

    Synthetic Glycopolymers into Cellular Membranes. ” J. Am.between siRNA Localization, Cellular Uptake, and RNAi inas an Anti-Tumor Drig: Cellular Mechanisms of Activity, Drug

  8. Development of a removable conformal coating through the synthetic...

    Office of Scientific and Technical Information (OSTI)

    Conference: Development of a removable conformal coating through the synthetic incorporation of Diels-Adler thermally reversible adducts into an epoxy resin. Citation Details...

  9. Inversion of synthetic aperture radar interferograms for sources...

    Open Energy Info (EERE)

    Inversion of synthetic aperture radar interferograms for sources of production-related subsidence at the Dixie Valley geothermal field Jump to: navigation, search OpenEI Reference...

  10. On Biology as an Emergent Science

    E-Print Network [OSTI]

    H. Pierre Noyes

    2007-05-31

    Biology is considered here as an "emergent science" in the sense of Anderson and of Laughlin and Pines. It is demonstrated that a straightforward mathematical definition of "biological system" is useful in showing how biology differs in structure from the lower levels in Anderson's "More is Different" hierarchy. Using cells in a chemostat as a paradigmatic exemplar of a biological system, it is found that a coherent collection of metabolic pathways through a single cell in the chemostat also satisfies the proposed definition of a biological system. This provides a theoretical and mathematical underpinning for Young's fundamental model of biological organization and integration. Evidence for the therapeutic efficacy of Young's method of analysis is provided by preliminary results of clinical trials of a specific application of Young's model to the treatment of cancer cachexia.

  11. Synthetic magnetoelectric coupling in a nanocomposite multiferroic

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Jain, P.; Wang, Q.; Roldan, M.; Glavic, A.; Lauter, V.; Urban, C.; Bi, Z.; Ahmed, T.; Zhu, J.; Varela, M.; et al

    2015-03-13

    Given the paucity of single phase multiferroic materials (with large ferromagnetic moment), composite systems seem an attractive solution to realize magnetoelectric coupling between ferromagnetic and ferroelectric order parameters. Despite having antiferromagnetic order, BiFeO? (BFO) has nevertheless been a key material due to excellent ferroelectric properties at room temperature. We studied a superlattice composed of 8 repetitions of 6 unit cells of La?.?Sr?.?MnO? (LSMO) grown on 5 unit cells of BFO. Significant net uncompensated magnetization in BFO, an insulating superlattice, is demonstrated using polarized neutron reflectometry. Remarkably, the magnetization enables magnetic field to change the dielectric properties of the superlattice, whichmore »we cite as an example of synthetic magnetoelectric coupling. Importantly, controlled creation of magnetic moment in BFO is a much needed path toward design and implementation of integrated oxide devices for next generation magnetoelectric data storage platforms.« less

  12. FOREST ENTOMOLOGY Blending Synthetic Pheromones of Cerambycid Beetles to Develop

    E-Print Network [OSTI]

    Hanks, Lawrence M.

    (F.),Neoclytusmucronatus(F.),andXylotrechuscolonus(F.).Beetlesofthesespecieswere signiÞcantly attracted to synthetic blends that contained their pheromone components (isomers of 3FOREST ENTOMOLOGY Blending Synthetic Pheromones of Cerambycid Beetles to Develop Trap Lures.1603/EC11434 ABSTRACT We evaluated attraction of cerambycid beetle species to blends of known cerambycid

  13. Module Identification for Biological Networks 

    E-Print Network [OSTI]

    Wang, Yijie

    2015-08-12

    into the Deoxyri- bonucleic acid (DNA), which is a molecule that stores the genetic instructions used in all biological processes of all known living organisms. Human Genome Project (HGP) has achieved tremendous success in determining the DNA sequence and rec...- ognizing and mapping genes of the human genome based on both their physical and functional responsibilities. However, HGP collaborated all research pioneers around the world and still costed 13 years and $3 billions, which illustrates how difficult...

  14. Plant Vascular Biology 2010

    SciTech Connect (OSTI)

    Ding, Biao

    2014-11-17

    This grant supported the Second International Conference on Plant Vascular Biology (PVB 2010) held July 24-28, 2010 on the campus of Ohio State University, Columbus, Ohio. Biao Ding (Ohio State University; OSU) and David Hannapel (Iowa State University; ISU) served as co-chairs of this conference. Biao Ding served as the local organizer. PVB is defined broadly here to include studies on the biogenesis, structure and function of transport systems in plants, under conditions of normal plant growth and development as well as of plant interactions with pathogens. The transport systems cover broadly the xylem, phloem, plasmodesmata and vascular cell membranes. The PVB concept has emerged in recent years to emphasize the integrative nature of the transport systems and approaches to investigate them.

  15. Splicing bioinformatics to biology

    E-Print Network [OSTI]

    Black, Douglas L; Graveley, Brenton R

    2006-01-01

    Splicing bioinformatics to biology Douglas L Black* andand Developmental Biology, University of Connecticut Health26 May 2006 Genome Biology 2006, 7:317 (doi:10.1186/gb-2006-

  16. Target Discrimination in Synthetic Aperture Radar (SAR) using Artificial Neural Networks 1 TargetDiscriminationinSyntheticApertureRadar(SAR)

    E-Print Network [OSTI]

    Slatton, Clint

    Target Discrimination in Synthetic Aperture Radar (SAR) using Artificial Neural Networks 1 Target principe@cnel.ufl.edu Abstract: This paper addresses target discrimination in synthetic aperture radar (SAR classification but here the goal is discrimination. We will show that the two applications require different cost

  17. Microfluidics for quantitative biology

    E-Print Network [OSTI]

    Adler, Micha

    2012-01-01

    CALIFORNIA, SAN DIEGO Microfluidics for Quantitative BiologyChapter 1: Microfluidics.………………………………………………………..… 1 1.1OF THE DISSERTATION Microfluidics for Quantitative Biology

  18. Motion Measurement for Synthetic Aperture Radar.

    SciTech Connect (OSTI)

    Doerry, Armin W.

    2015-01-01

    Synthetic Aperture Radar (SAR) measures radar soundings from a set of locations typically along the flight path of a radar platform vehicle. Optimal focusing requires precise knowledge of the sounding source locations in 3 - D space with respect to the target scene. Even data driven focusing techniques (i.e. autofocus) requires some degree of initial fidelity in the measurements of the motion of the radar. These requirements may be quite stringent especially for fine resolution, long ranges, and low velocities. The principal instrument for measuring motion is typically an Inertial Measurement Unit (IMU), but these instruments have inherent limi ted precision and accuracy. The question is %22How good does an IMU need to be for a SAR across its performance space?%22 This report analytically relates IMU specifications to parametric requirements for SAR. - 4 - Acknowledgements Th e preparation of this report is the result of a n unfunded research and development activity . Although this report is an independent effort, it draws heavily from limited - release documentation generated under a CRADA with General Atomics - Aeronautical System, Inc. (GA - ASI), and under the Joint DoD/DOE Munitions Program Memorandum of Understanding. Sandia National Laboratories is a multi - program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of En ergy's National Nuclear Security Administration under contract DE - AC04 - 94AL85000.

  19. Naphthene upgrading with pillared synthetic clay catalysts

    SciTech Connect (OSTI)

    Sharma, R.K.; Olson, E.S. [Univ. of North Dakota, Grand Forks, ND (United States)

    1995-12-31

    Catalytic hydrotreatment of methylcyclohexane was investigated to model upgrading of coal-derived naphthenes. Nickel-substituted synthetic mica montmorillonite (NiSMM), alumina-pillared NiSMM and Zirconia-pillared NiSMM were prepared and tested for hydrocracking and hydroisomerization of methylcyclohexane. Infrared and thermal desorption studies of the pyridine-adsorbed catalysts indicated the presence of Lewis and Bronsted acid sites. Total acidity and surface area increased with pillaring of NiSMM with polyoxy aluminum and polyoxy zirconium cations. Methylcyclohexane was reacted with these catalysts under a variety of conditions. Pillared clays gave higher gas yields and higher hydrocracking but lower hydroisomerization activity than nonpillared clay. The majority of the products were branched alkanes (isoparaffinic). These catalysts effectively use hydrogen as indicated by the minimal formation of aromatic hydrocarbons, coke, or other oligomeric materials. The effect of various operating conditions, i.e., reaction temperature, contact time, H{sub 2} pressure, and catalyst, on the product distribution will be described.

  20. Metabolic engineering of microorganisms for biofuels production: from bugs to synthetic biology to fuels

    E-Print Network [OSTI]

    Kuk Lee, Sung

    2010-01-01

    Fuels Maximizing solar energy conversion to chemical storagethat maximize solar energy conversion to chemical storage

  1. RIKEN Center for Life Science Technologies Division of Structural and Synthetic Biology

    E-Print Network [OSTI]

    Fukai, Tomoki

    Function Conversion Technology Team Genetic Diagnosis Technology Unit Epigenome Technology Exploration Unit Cell Conversion Technology Unit Genome Network Analysis Support Facility Nucleic Acid Diagnostic System Structural Bioinformatics Team Post-Transcriptional Control Research Unit Translation Factors Structural

  2. Synthetic biology projects in vitro Anthony C. Forster1,3

    E-Print Network [OSTI]

    Church, George M.

    , materials, and energy (Silver and Way 2004) (http://syntheticbiology.org). As a bonus, genetic systems SBPs for large- scale production/conversion of materials. Neobiotic construc- tions with new functions and debugged with the aim of synthesizing life-like systems. The goals are knowledge, tools, smart materials

  3. Self-assembly of synthetic and biological components in water using cucurbit[8]uril

    E-Print Network [OSTI]

    Zayed, Jameel Majed

    2012-02-07

    fellow Welshman, who, like me, made it through the harsh, English-ruled marshlands of Cambridgeshire without getting tired of hearing the sheep joke; I thank you for keeping the fish tank, and its numerous Amazonian fish, in spick and span condition... solvents, as well as in nonpolar solvents. The use of alkyl- poly(ethylene glycol) (PEG) groups provides an elegant example of molecular design, ensuring water solubility while providing hydrophobic pockets69 that help shield the water-sensitive H...

  4. Synthetic Biology for Advanced Fuels (Opening Keynote Address - 2010 JGI User Meeting)

    ScienceCinema (OSTI)

    Keasling, Jay

    2011-04-28

    Jay Keasling, CEO of the Joint BioEnergy Institute, delivers the opening keynote on March 24, 2010 at the 5th Annual DOE JGI User Meeting

  5. Metabolic engineering of microorganisms for biofuels production: from bugs to synthetic biology to fuels

    E-Print Network [OSTI]

    Kuk Lee, Sung

    2010-01-01

    of microbial hosts for biofuels production. Metab Eng 2008,delivers next-generation biofuels. Nat Biotechnol 27.furfural (HMF). Biotechnol Biofuels 2008, 1:12. 40. Trinh

  6. Flourishing and Discordance: On Two Modes of Human Science Engagement with Synthetic Biology

    E-Print Network [OSTI]

    Stavrianakis, Anthony

    2012-01-01

    just as with the Human Genome Project, dedicated researchELSI) model of the Human Genome Project and the ‘lab study’ELSI) model of the Human Genome Project. ELSI. Remediations

  7. Flourishing and Discordance: On Two Modes of Human Science Engagement with Synthetic Biology

    E-Print Network [OSTI]

    Stavrianakis, Anthony

    2012-01-01

    cool in his sober, practical tone, began by outlining the new vision for the thrust: “benefit everyone and the planet,

  8. Open collaborative system design : a strategic framework with application to synthetic biology

    E-Print Network [OSTI]

    Silver, Matthew Robin

    2010-01-01

    Across technology industries and particularly at the cutting edge of biotechnology a debate is under way about the proper balance between open and closed - between co-developing products with shared information and open ...

  9. Biological and Synthetic Locomotion in Newtonian and Complex Fluids at Low Reynolds Number

    E-Print Network [OSTI]

    Pak, On Shun

    Fischer. Controlled propulsion of artificial magnetic nanos-of the magnetic field leads to propulsion in the oppositepredict the propulsion speed under different magnetic field

  10. Metabolic engineering of microorganisms for biofuels production: from bugs to synthetic biology to fuels

    E-Print Network [OSTI]

    Kuk Lee, Sung

    2010-01-01

    1014. 24. Chisti Y: Biodiesel from microalgae. Biotechnolcorn) or sugar cane and biodiesel produced from vegetableenergy content of gasoline. Biodiesel has similar problems (

  11. Metabolic engineering of microorganisms for biofuels production: from bugs to synthetic biology to fuels

    E-Print Network [OSTI]

    Kuk Lee, Sung

    2010-01-01

    economically viable biofuel production, all aspects of thesemany challenges on biofuel production [1,3 ,28-30]. Some ofhigh-flux reactions. Biofuel production efforts can benefit

  12. computational modeling of biological systems

    E-Print Network [OSTI]

    $author.value

    Faculty. Faculty listing for "computational modeling of biological systems" ... Research Interests: computational modeling of biological systems.

  13. Computational optimization of synthetic water channels.

    SciTech Connect (OSTI)

    Rogers, David Michael; Rempe, Susan L. B.

    2012-12-01

    Membranes for liquid and gas separations and ion transport are critical to water purification, osmotic energy generation, fuel cells, batteries, supercapacitors, and catalysis. Often these membranes lack pore uniformity and robustness under operating conditions, which can lead to a decrease in performance. The lack of uniformity means that many pores are non-functional. Traditional membranes overcome these limitations by using thick membrane materials that impede transport and selectivity, which results in decreased performance and increased operating costs. For example, limitations in membrane performance demand high applied pressures to deionize water using reverse osmosis. In contrast, cellular membranes combine high flux and selective transport using membrane-bound protein channels operating at small pressure differences. Pore size and chemistry in the cellular channels is defined uniformly and with sub-nanometer precision through protein folding. The thickness of these cellular membranes is limited to that of the cellular membrane bilayer, about 4 nm thick, which enhances transport. Pores in the cellular membranes are robust under operating conditions in the body. Recent efforts to mimic cellular water channels for efficient water deionization produced a significant advance in membrane function. The novel biomimetic design achieved a 10-fold increase in membrane permeability to water flow compared to commercial membranes and still maintained high salt rejection. Despite this success, there is a lack of understanding about why this membrane performs so well. To address this lack of knowledge, we used highperformance computing to interrogate the structural and chemical environments experienced by water and electrolytes in the newly created biomimetic membranes. We also compared the solvation environments between the biomimetic membrane and cellular water channels. These results will help inform future efforts to optimize and tune the performance of synthetic biomimetic membranes for applications in water purification, energy, and catalysis.

  14. Synthetic strategies for the design of platinum anticancer drug candidates

    E-Print Network [OSTI]

    Wilson, Justin Jeff

    2013-01-01

    Chapter 1. The Synthetic Chemistry of Platinum Anticancer Agents Since the inception of cisplatin as a clinically approved anticancer agent, a large number of platinum compounds have been synthesized with the aim of finding ...

  15. A Transport Synthetic Acceleration method for transport iterations 

    E-Print Network [OSTI]

    Ramone, Gilles Lionel

    1996-01-01

    We present a family of Transport Synthetic Acceleration (TSA) methods to iteratively solve within-group scattering problems. A single iteration in these schemes consists of a transport sweep followed by a low-order calculation ...

  16. Synthetic scaffolds and protein assemblies for engineering applications

    E-Print Network [OSTI]

    Norville, Julie Erin, 1980-

    2004-01-01

    S-layer proteins, which naturally self-assemble on the exterior of cells, provide an interesting basis for the creation of synthetic scaffolds. In this thesis, I created a plasmid which produces a recombinant form of a ...

  17. Development of a synthetic phase contrast imaging diagnostic

    E-Print Network [OSTI]

    Rost, Jon C.

    A “synthetic diagnostic” has been developed to calculate the expected experimental response of phase contrast imaging (PCI), a scattering diagnostic used to measure density fluctuations in laboratory plasmas, to a tokamak ...

  18. Expansion of Automotive Industries to Boost the Global Synthetic...

    Open Energy Info (EERE)

    on the key players in the global synthetic and bio-based lubricants market such as BP plc, Chevron, and Exxon Mobil Corporation, including financial overview, data gained from...

  19. Recent and future trends in synthetic greenhouse gas radiative forcing

    E-Print Network [OSTI]

    O'Doherty, S.

    Atmospheric measurements show that emissions of hydrofluorocarbons (HFCs) and hydrochlorofluorocarbons are now the primary drivers of the positive growth in synthetic greenhouse gas (SGHG) radiative forcing. We infer recent ...

  20. Biology & Biomedical Sciences ACADEMIC PROGRAM

    E-Print Network [OSTI]

    Gereau, Robert W. IV

    Biology & Biomedical Sciences ACADEMIC PROGRAM GUIDELINES Programs in Cell & Molecular Biology Developmental, Regenerative and Stem Cell Biology Molecular Cell Biology Molecular Genetics & Genomics Molecular Microbiology & Microbial Pathogenesis #12;PAGE 2 GUIDELINES TO THE PROGRAMS IN CELL AND MOLECULAR BIOLOGY

  1. Synthetic reverberating activity patterns embedded in networks of cortical neurons

    E-Print Network [OSTI]

    Roni Vardi; Avner Wallach; Evi Kopelowitz; Moshe Abeles; Shimon Marom; Ido Kanter

    2012-03-26

    Synthetic reverberating activity patterns are experimentally generated by stimulation of a subset of neurons embedded in a spontaneously active network of cortical cells in-vitro. The neurons are artificially connected by means of conditional stimulation matrix, forming a synthetic local circuit with a predefined programmable connectivity and time-delays. Possible uses of this experimental design are demonstrated, analyzing the sensitivity of these deterministic activity patterns to transmission delays and to the nature of ongoing network dynamics.

  2. Scaling Issues for VLSI Implementations of Biologically Accurate Neurons and Central Pattern Generators

    E-Print Network [OSTI]

    Ayers, Joseph

    Generators Daniel DeBolt Electrical and Computer Engineering Northeastern University Boston, Massachusetts generation for the Cyberplasm program that is an effort to apply principles of synthetic biology ddebolt@ece.neu.edu Yong-Bin Kim Electrical and Computer Engineering Northeastern University Boston

  3. University of Maryland Center for Environmental Science Chesapeake Biological Laboratory

    E-Print Network [OSTI]

    Boynton, Walter R.

    , the Chesapeake Biological Laboratory has long been a national leader in fisheries, environmental chemistry. Beaven Hall Environmental Chemistry & Toxicology Understanding the fate of pollutants their work in two primary areas: aquatic toxicology and environmental organic chemistry. Aquatic

  4. The physical, environmental, and evolutionary determinants of biological architecture

    E-Print Network [OSTI]

    Kempes, Christopher Andrew Poling

    2013-01-01

    The relationship between structure and function is a longstanding and central topic in biology, evolution, and ecology. The importance of morphology is clearly visible in the diverse forms taken by innumerable organisms ...

  5. The tragedy of the commons in evolutionary biology

    E-Print Network [OSTI]

    Rankin, Daniel

    The tragedy of the commons in evolutionary biology Daniel J. Rankin1,2 , Katja Bargum3 and Hanna, which raises the question of how non-human organisms manage to resolve similar tragedies. In recent

  6. Mathematical Biology 3 Jurgen Jost

    E-Print Network [OSTI]

    Arnold, Anton

    Mathematical Biology 3 J¨urgen Jost Max Planck Institute for Mathematics in the Sciences Leipzig, Germany Mathematical Biology 3 ­ p. 1 #12;Biological networks In biology, we find many examples of interacting elements: Mathematical Biology 3 ­ p. 2 #12;Biological networks In biology, we find many examples

  7. CEL October 2006 Cell biology overview

    E-Print Network [OSTI]

    -electron therapy Multi-purpose projects · Cell nursing in 2D and 3D · Optical nanosensors Tools · Molecular biology be coupled to immobilized avidin In mold patterning of avidin makes it possible to structure the surface immune response to transplanted organs Aim Effects Materials Methods To discover antibodies in blood

  8. Mathematics,Biology,and Physics:Interactionsand

    E-Print Network [OSTI]

    Bokil, Vrushali

    . The first electric generating machines and the Leyden jar were constructed to produce static electricity electromagnetic fields and biological tissues. This includes the generation of electric or magnetic fields and electric currents in some specialized organs, the intrinsic electric and magnetic properties of tissue

  9. Commercial Fisheries Biological Laboratory

    E-Print Network [OSTI]

    Bureau of Commercial Fisheries Biological Laboratory Oxford, Maryland #12;Chart of the Tred Avon River, showing the location of the BCF Biological Laboratory and the orientation of this area modern laboratories for chem- ical, histological, microbiological, and physiological re- search

  10. Semiconductor Nanocrystals for Biological Imaging

    SciTech Connect (OSTI)

    Fu, Aihua; Gu, Weiwei; Larabell, Carolyn; Alivisatos, A. Paul

    2005-06-28

    Conventional organic fluorophores suffer from poor photo stability, narrow absorption spectra and broad emission feature. Semiconductor nanocrystals, on the other hand, are highly photo-stable with broad absorption spectra and narrow size-tunable emission spectra. Recent advances in the synthesis of these materials have resulted in bright, sensitive, extremely photo-stable and biocompatible semiconductor fluorophores. Commercial availability facilitates their application in a variety of unprecedented biological experiments, including multiplexed cellular imaging, long-term in vitro and in vivo labeling, deep tissue structure mapping and single particle investigation of dynamic cellular processes. Semiconductor nanocrystals are one of the first examples of nanotechnology enabling a new class of biomedical applications.

  11. Chemistry & Biology Brief Communication

    E-Print Network [OSTI]

    Zhao, Huimin

    Chemistry & Biology Brief Communication Cloning, IL 61801, USA 3Department of Chemistry 4Department of Chemical and Biomolecular Engineering

  12. Biological Frameworks for Engineers ME 411 / ME511

    E-Print Network [OSTI]

    Sniadecki, Nathan J.

    nd Edition, Garland Press, ISBN: 0815332823 3) Alberts et al. Molecular Biology of the Cell, Garland://courses.washington.edu/nsniadec/ME411/A12 Course Description: Introduction to the fundamentals of biology for an engineer. Mechanisms to Biomechanics: From Cells to Organisms, Cambridge University Press, ISBN: 0521841127 2) Bray, Cell Movements, 2

  13. Scientific Correspondence Chemical Genetic Approaches to Plant Biology1

    E-Print Network [OSTI]

    Zhao, Yunde

    the desired natural products out of the plant tissues, in fact, pharmacognostic endeavors with natural view plants as sources of diverse and structurally complex organic molecules (i.e. nat- ural products), frequently with exquisite biological activities. Little knowledge of plant biology is re- quired to extract

  14. Computational Biology | More Science | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Computational Biology SHARE Computational Biology Computational Biology research encompasses many important aspects including molecular biophysics for bio-energy, genetic level...

  15. A Central Theory of Biology

    E-Print Network [OSTI]

    Torday, JS

    2015-01-01

    JS, Rehan VK. Evolutionary biology, cell–cell communication6] Torday JS. Evolutionary Biology Redux. Pers Biol Med 56,explanations in evolutionary biology. Hist Philos Life Sci

  16. Systems biology approach to bioremediation

    E-Print Network [OSTI]

    Chakraborty, R.

    2013-01-01

    aspects of the systems biology approach (metagenomics withthe use of a number of sytems biology parameters can revealRL, Banfield JF: Systems Biology: functional analysis of

  17. Todd Newberry: Professor of Biology

    E-Print Network [OSTI]

    Newberry, Andrew Todd; Jarrell, Randall; Regional History Project, UCSC Library

    2006-01-01

    Todd Newberry, Professor of Biology: Cowell College page 12Jarrell: Why’s that? Todd Newberry, Professor of Biology:Biology Board page 14 Newberry: Well, besides the

  18. HARVARD UNIVERSITY CHEMICAL BIOLOGY

    E-Print Network [OSTI]

    Church, George M.

    HARVARD UNIVERSITY CHEMICAL BIOLOGY PHD PROGRAM 2013-2014 Student Handbook #12;Program Contacts at the beginning of each semester. Laboratory Rotations Students in the Chemical Biology Program are expected an interest in having Chemical Biology Program Students in their labs. Students may rotate in the labs

  19. Analysis of differences in productivity, profitability and soil fertility between organic and conventional cropping systems in the (sub)tropics 

    E-Print Network [OSTI]

    te Pas, Caroline M.

    2011-11-24

    Organic farming, which aims at increasing soil fertility by avoiding synthetic inputs and using locally available natural resources, is regarded as a sustainable alternative to conventional farming because it ensures ...

  20. Designer synthetic media for studying microbial-catalyzed biofuel production

    SciTech Connect (OSTI)

    Tang, Xiaoyu [Biogas Inst. of Ministry of Agriculture, Chengdu (China); da Costa Sousa, Leonardo [Michigan State Univ., East Lansing, MI (United States); Jin, Mingjie [Michigan State Univ., East Lansing, MI (United States); Chundawat, Shishir [Michigan State Univ., East Lansing, MI (United States); State Univ. of New Jersey, Piscataway, NJ (United States); Chambliss, Charles [Baylor Univ., Waco, TX (United States); Lau, Ming W [Michigan State Univ., East Lansing, MI (United States); Xiao, Zeyi [Sichuan Univ., Chengdu (China); Dale, Bruce E [Michigan State Univ., East Lansing, MI (United States); Balan, Venkatesh [Michigan State Univ., East Lansing, MI (United States)

    2015-01-01

    Background: The fermentation inhibition of yeast or bacteria by lignocellulose-derived degradation products, during hexose/pentose co-fermentation, is a major bottleneck for cost-effective lignocellulosic biorefineries. To engineer microbial strains for improved performance, it is critical to understand the mechanisms of inhibition that affect fermentative organisms in the presence of major components of a lignocellulosic hydrolysate. The development of a synthetic lignocellulosic hydrolysate (SH) media with a composition similar to the actual biomass hydrolysate will be an important advancement to facilitate these studies. In this work, we characterized the nutrients and plant-derived decomposition products present in AFEX™ pretreated corn stover hydrolysate (ACH). The SH was formulated based on the ACH composition and was further used to evaluate the inhibitory effects of various families of decomposition products during Saccharomyces cerevisiae 424A (LNH-ST) fermentation. Results: The ACH contained high levels of nitrogenous compounds, notably amides, pyrazines, and imidazoles. In contrast, a relatively low content of furans and aromatic and aliphatic acids were found in the ACH. Though most of the families of decomposition products were inhibitory to xylose fermentation, due to their abundance, the nitrogenous compounds showed the most inhibition. From these compounds, amides (products of the ammonolysis reaction) contributed the most to the reduction of the fermentation performance. However, this result is associated to a concentration effect, as the corresponding carboxylic acids (products of hydrolysis) promoted greater inhibition when present at the same molar concentration as the amides. Due to its complexity, the formulated SH did not perfectly match the fermentation profile of the actual hydrolysate, especially the growth curve. However, the SH formulation was effective for studying the inhibitory effect of various compounds on yeast fermentation. Conclusions: The formulation of SHs is an important advancement for future multi-omics studies and for better understanding the mechanisms of fermentation inhibition in lignocellulosic hydrolysates. The SH formulated in this work was instrumental for defining the most important inhibitors in the ACH. Major AFEX decomposition products are less inhibitory to yeast fermentation than the products of dilute acid or steam explosion pretreatments; thus, ACH is readily fermentable by yeast without any detoxification.

  1. Designer synthetic media for studying microbial-catalyzed biofuel production

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Tang, Xiaoyu; da Costa Sousa, Leonardo; Jin, Mingjie; Chundawat, Shishir; Chambliss, Charles; Lau, Ming W; Xiao, Zeyi; Dale, Bruce E; Balan, Venkatesh

    2015-01-01

    Background: The fermentation inhibition of yeast or bacteria by lignocellulose-derived degradation products, during hexose/pentose co-fermentation, is a major bottleneck for cost-effective lignocellulosic biorefineries. To engineer microbial strains for improved performance, it is critical to understand the mechanisms of inhibition that affect fermentative organisms in the presence of major components of a lignocellulosic hydrolysate. The development of a synthetic lignocellulosic hydrolysate (SH) media with a composition similar to the actual biomass hydrolysate will be an important advancement to facilitate these studies. In this work, we characterized the nutrients and plant-derived decomposition products present in AFEX™ pretreated corn stover hydrolysate (ACH). Themore »SH was formulated based on the ACH composition and was further used to evaluate the inhibitory effects of various families of decomposition products during Saccharomyces cerevisiae 424A (LNH-ST) fermentation. Results: The ACH contained high levels of nitrogenous compounds, notably amides, pyrazines, and imidazoles. In contrast, a relatively low content of furans and aromatic and aliphatic acids were found in the ACH. Though most of the families of decomposition products were inhibitory to xylose fermentation, due to their abundance, the nitrogenous compounds showed the most inhibition. From these compounds, amides (products of the ammonolysis reaction) contributed the most to the reduction of the fermentation performance. However, this result is associated to a concentration effect, as the corresponding carboxylic acids (products of hydrolysis) promoted greater inhibition when present at the same molar concentration as the amides. Due to its complexity, the formulated SH did not perfectly match the fermentation profile of the actual hydrolysate, especially the growth curve. However, the SH formulation was effective for studying the inhibitory effect of various compounds on yeast fermentation. Conclusions: The formulation of SHs is an important advancement for future multi-omics studies and for better understanding the mechanisms of fermentation inhibition in lignocellulosic hydrolysates. The SH formulated in this work was instrumental for defining the most important inhibitors in the ACH. Major AFEX decomposition products are less inhibitory to yeast fermentation than the products of dilute acid or steam explosion pretreatments; thus, ACH is readily fermentable by yeast without any detoxification.« less

  2. Fermilab | About | Organization | Fermilab Organization | Explanation...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of Symbols Line Organization: sectors, divisions, sections Line Organization Matrix Organization: centers, projects and programs utilizing resources spanning the entire...

  3. Apparatus, systems, and methods for ultrasound synthetic aperature focusing

    DOE Patents [OSTI]

    Schuster, George J.; Crawford, Susan L.; Doctor, Steven R.; Harris, Robert V.

    2005-04-12

    One form of the present invention is a technique for interrogating a sample with ultrasound which includes: generating ultrasonic energy data corresponding to a volume of a sample and performing a synthetic aperture focusing technique on the ultrasonic energy data. The synthetic aperture focusing technique includes: defining a number of hyperbolic surfaces which extend through the volume at different depths and a corresponding number of multiple element accumulation vectors, performing a focused element calculation procedure for a group of vectors which are representative of the interior of a designated aperture, performing another focused element calculation procedure for vectors corresponding to the boundary of the aperture, and providing an image corresponding to features of the sample in accordance with the synthetic aperture focusing technique.

  4. BIOLOGY, B.S. WITH TEACHER CERTIFICATE Biology (BIOT)

    E-Print Network [OSTI]

    Hamburger, Peter

    BIOLOGY, B.S. WITH TEACHER CERTIFICATE Biology (BIOT) (Fall 2015-Summer 2016) IPFW Residency/Gen Ed Biology BS Core/Supporting Courses (64 credits) *Note: 3.0 GPA required in Biology Core 21800 Genetics & Molecular Biology ______ 4 BIOL 21900 Principles of Functional Biology ______ 3 BIOL

  5. Chemistry & Biology Brief Communication

    E-Print Network [OSTI]

    van Aalten, Daan

    plant-type chitinase reveals that the compound binds the catalytic machinery in the same manner synthesis of derivatives to explore a pocket near the catalytic machinery. This work provides synthetically of enzymes of interest and the design of future therapeutic drugs. Argifin is a natural product

  6. Kapitza problem for the magnetic moments of synthetic antiferromagnetic systems

    SciTech Connect (OSTI)

    Dzhezherya, Yu. I.; Demishev, K. O.; Korenivskii, V. N.

    2012-08-15

    The dynamics of magnetization in synthetic antiferromagnetic systems with the magnetic dipole coupling in a rapidly oscillating field has been examined. It has been revealed that the system can behave similar to the Kapitza pendulum. It has been shown that an alternating magnetic field can be efficiently used to control the magnetic state of a cell of a synthetic antiferromagnet. Analytical relations have been obtained between the parameters of such an antiferromagnet and an external magnetic field at which certain quasistationary states are implemented.

  7. Resolution and synthetic aperture characterization of sparse radar arrays

    E-Print Network [OSTI]

    Stiles, James Marion; Goodman, N. A.

    2003-07-01

    : RESOLUTION AND SYNTHETIC APERTURE CHARACTERIZATION 923 position in each of three spatial directions. These are, by definition, the spatial frequencies k x (x), k y (x), and k z (x) of the wave scattered from a target at x. Likewise, the fourth term provides..., the transmitting antenna can be focused on the mean scatterer location ¯ x by forcing a phase taper of ª a (l)=#0;?(k 0 l ) † ¢l: (24) Then, the transmit pattern is g(x)= #0;= S A #0;Mw l (l)#0;Mexp(#0;?j¢x † ¤ l ¢l)dl: (25) B. Synthetic Aperture Interpretation...

  8. 2013 METALS IN BIOLOGY GORDON RESEARCH CONFERENCE, JANUARY 20-25, 2013

    SciTech Connect (OSTI)

    Rosenzweig, Amy

    2013-01-25

    Typical topics for lectures and posters include: biochemical and biophysical characterization of new metal containing proteins, enzymes, nucleic acids, factors, and chelators from all forms of life; synthesis, detailed characterization, and reaction chemistry of biomimetic compounds; novel crystal and solution structures of biological molecules and synthetic metal-chelates; discussions of the roles that metals play in medicine, maintenance of the environment, and biogeochemical processes; metal homeostasis; application of theory and computations to the structure and mechanism of metal-containing biological systems; and novel applications of spectroscopy to metals in biological systems.

  9. Invasion Biology Mark A. Davis

    E-Print Network [OSTI]

    Davis, Mark A.

    Invasion Biology Mark A. Davis 2 biology 2 MarkA.DavisInvasionBiology2 1 With the exception of climate change, biological invasions have probably received more attention during the past ten years than on the subject, Invasion Biology provides a comprehensive and up-to-date review of the science of biological

  10. Factors Contributing to Petroleum Foaming. 2. Synthetic Crude Oil Systems

    E-Print Network [OSTI]

    Kilpatrick, Peter K.

    Factors Contributing to Petroleum Foaming. 2. Synthetic Crude Oil Systems Nael N. Zaki, Michael K to the petroleum industry. Nonaqueous foams occur in the production of and refining of crude oil. Crude oil foams can pose major problems for operators of gas/oil separation plants, causing a loss of crude

  11. Co-transport of H+ by a synthetic prodigiosin mimic{

    E-Print Network [OSTI]

    Smith, Bradley D.

    Co-transport of H+ /Cl2 by a synthetic prodigiosin mimic{ Philip A. Gale,*a Mark E. Light,a Beth Mc.1039/b503906a An amidopyrrole with appended imidazole group can bind and co-transport H+ /Cl2 across of the weak bases are compounds that act as H+ /Cl2 co-transporters. The best known examples

  12. SPE-163690-MS Synthetic, Geomechanical Logs for Marcellus Shale

    E-Print Network [OSTI]

    Mohaghegh, Shahab

    SPE-163690-MS Synthetic, Geomechanical Logs for Marcellus Shale M. O. Eshkalak, SPE, S. D of hydrocarbons from the reservoirs, notably shale, is attributed to realizing the key fundamentals of reservoir and mineralogy is crucial in order to identify the "right" pay-zone intervals for shale gas production. Also

  13. Library of libraries: A novel approach in synthetic combinatorial libraries

    E-Print Network [OSTI]

    Lam, Kit S.

    are defined. In other words, the first step of the iterative process consists of screening libraries with veryLibrary of libraries: A novel approach in synthetic combinatorial libraries Nikolai F. Sepetov peptide libraries for pharmacological purposes is not necessarily to find the most active peptide

  14. New synthetic derivatives of triterpenoids in the treatment of cancer 

    E-Print Network [OSTI]

    Papineni, Sabitha

    2009-05-15

    Methyl 2-cyano-3,11-dioxo-18?-olean-1,12-dien-30-oate (?-CDODA-Me) and methyl 2-cyano-3,11-dioxo-18?-olean-1,12-dien-30-oate (?-CDODA-Me ) isomers are synthetic analogs of the naturally occurring triterpenoid glycyrrhetinic ...

  15. HIGH SCHOOL PHYSICS PATHWAY: TEACHERS HELPING TEACHERS THROUGH SYNTHETIC INTERVIEWS*

    E-Print Network [OSTI]

    , physics pedagogy, physics education 1. INTRODUCTION Physics Teaching Web Advisory (Pathway) is a researchHIGH SCHOOL PHYSICS PATHWAY: TEACHERS HELPING TEACHERS THROUGH SYNTHETIC INTERVIEWS* *Published the iterative development of a dynamic web environment for exploring physics pedagogy: the Physics Teaching Web

  16. Electricity Generation from Synthetic Acid-Mine Drainage (AMD) Water

    E-Print Network [OSTI]

    Electricity Generation from Synthetic Acid-Mine Drainage (AMD) Water using Fuel Cell Technologies, 2007. Acid-mine drainage (AMD) is difficult and costly to treat. We investigated a new approach to AMD and systems suitable for scale-up. Introduction Acid-mine drainage (AMD) is a serious environmental problem

  17. Passive Synthetic Aperture Radar Imaging of Ground Moving Targets

    E-Print Network [OSTI]

    Yazici, Birsen

    waves due to illuminating sources of opportunity such as commercial television, radio, and cell phone of opportunity such as radio, cell phone, and television transmission towers. The absence of active signal synthetic aperture radar. A passive radar imaging system uses small, mobile receivers that do not radiate

  18. Synthetic aperture design for increased SAR image rate

    DOE Patents [OSTI]

    Bielek, Timothy P. (Albuquerque, NM); Thompson, Douglas G. (Albuqerque, NM); Walker, Bruce C. (Albuquerque, NM)

    2009-03-03

    High resolution SAR images of a target scene at near video rates can be produced by using overlapped, but nevertheless, full-size synthetic apertures. The SAR images, which respectively correspond to the apertures, can be analyzed in sequence to permit detection of movement in the target scene.

  19. Tunable Signal Processing in Synthetic MAP Kinase Cascades

    E-Print Network [OSTI]

    Collins, James J.

    Tunable Signal Processing in Synthetic MAP Kinase Cascades Ellen C. O'Shaughnessy,1 Santhosh Palani profiles. This work demonstrates that tunable signal processing is inherent to minimal MAPK modules are ubiquitous, versatile signaling modules found in all eukaryotic cells. They transmit and process signals

  20. The formation and evolution of synthetic jets Barton L. Smitha)

    E-Print Network [OSTI]

    Smith, Barton L.

    The formation and evolution of synthetic jets Barton L. Smitha) and Ari Glezer Woodruff School 1997; accepted 6 May 1998 A nominally plane turbulent jet is synthesized by the interactions of a train of a flexible diaphragm in a sealed cavity. Even though the jet is formed without net mass injection

  1. Microwave-induced thermoacoustic tomography: Reconstruction by synthetic aperture

    E-Print Network [OSTI]

    Wang, Lihong

    Microwave-induced thermoacoustic tomography: Reconstruction by synthetic aperture Dazi Feng, Yuan thermoacoustic signals, to which the delay-and-sum algorithm was applied for image reconstruc- tion. We greatly-induced thermoacoustic tomography based on focused transducers. Two mi- crowave sources, which had frequencies of 9 and 3

  2. Magnetic characterization of synthetic titanomagnetites: Quantifying the recording

    E-Print Network [OSTI]

    Dunin-Borkowski, Rafal E.

    Kasama Centre for Electron Nanoscopy, Technical University of Denmark, Kongens Lyngby, Denmark Rafal, and transmission electron microscopy (TEM) demonstrate the reaction product composition consisted of mainly Fe3- x for visualization of the magnetic behavior of the synthetic Fe3-xTixO4 grains. Energy dispersive X-ray analysis

  3. Entrainment of a Population of Synthetic Genetic Oscillators

    E-Print Network [OSTI]

    Tsimring, Lev S.

    Entrainment of a Population of Synthetic Genetic Oscillators Octavio Mondragón-Palomino,1 Tal-sustained oscillators that adjust their phase to the daily environmental cycles in a process known as entrainment, but quantitative insights on the entrainment of clocks are relatively sparse. We simultaneously tracked the phases

  4. Matching a Human Walking Sequence with a VRML Synthetic Model

    E-Print Network [OSTI]

    Buades Rubio, Jose María

    animation, computer vision, medical rehabilitation, virtual reality and entertainment. There is a greatMatching a Human Walking Sequence with a VRML Synthetic Model J. M. Buades, Ramon Mas and Francisco University of the Balearic Islands 07071 Palma de Mallorca, SPAIN {josemaria,ramon,paco}@anim.uib.es Abstract

  5. A Protophenomenological Analysis of Synthetic Emotion in Robots

    E-Print Network [OSTI]

    MacLennan, Bruce

    J. MacLennan* Department of Electrical Engineering & Computer Science University of Tennessee?" (a chapter submitted for the Handbook of Research on Synthetic Emotions and Sociable Robotics: New a renaissance in the scientific investigation of consciousness, but a fundamental issue has been neglected

  6. Synthetic fuel aromaticity and staged combustion. First quarterly technical progress report, September 23-December 31, 1980

    SciTech Connect (OSTI)

    Levy, Arthur; Longanbach, James R.; Chan, Lisa K.

    1981-01-28

    Synthetic liquid fuels, otherwise referred to as synfuels or coal-derived liquids, are probably best characterized from a combustion-environmental point of view as low in hydrogen, low in sulfur, high in nitrogen, and high in aromatics. As a consequence two of the more critical problems in synfuel combustion are NO/sub x/ formation and soot formation (and polycyclic organic matter). This program is directed to these two issues. At first hand the solutions to burning synfuels high in aromatics and fuel-bound nitrogen are diametrically opposed, i.e., high temperature and excess air keep soot levels down, low temperatures and vitiated air keep nitrogen oxide levels down. Staged combustion however offers a logical solution to the above. This program separates and analyzes the synfuel combustion problem via its component parts and then puts them together again phenomenologically via the stage combustion process.

  7. Biological detector and method

    DOE Patents [OSTI]

    Sillerud, Laurel; Alam, Todd M; McDowell, Andrew F

    2014-04-15

    A biological detector includes a conduit for receiving a fluid containing one or more magnetic nanoparticle-labeled, biological objects to be detected and one or more permanent magnets or electromagnet for establishing a low magnetic field in which the conduit is disposed. A microcoil is disposed proximate the conduit for energization at a frequency that permits detection by NMR spectroscopy of whether the one or more magnetically-labeled biological objects is/are present in the fluid.

  8. Biological detector and method

    DOE Patents [OSTI]

    Sillerud, Laurel; Alam, Todd M; McDowell, Andrew F

    2013-02-26

    A biological detector includes a conduit for receiving a fluid containing one or more magnetic nanoparticle-labeled, biological objects to be detected and one or more permanent magnets or electromagnet for establishing a low magnetic field in which the conduit is disposed. A microcoil is disposed proximate the conduit for energization at a frequency that permits detection by NMR spectroscopy of whether the one or more magnetically-labeled biological objects is/are present in the fluid.

  9. Soil Biology & Biochemistry 39 (2007) 27012711 Carbon structure and enzyme activities in alpine and forest ecosystems

    E-Print Network [OSTI]

    Neff, Jason

    2007-01-01

    : Pyrolysis-gas chromatography/mass spectrometry; Py-GC/MS; Enzymes; Microbe; Carbon; Chemistry; Soil organicSoil Biology & Biochemistry 39 (2007) 2701­2711 Carbon structure and enzyme activities in alpine of soil organic matter fractions and its relationship to biological processes remains uncertain. We used

  10. Biology | More Science | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Atmospheric Sciences Materials Science and Engineering Mathematics Physics Environment Safety and Health More Science Home | Science & Discovery | More Science | Biology SHARE...

  11. Genomics and Systems Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Genomics and Systems Biology LANL leads the world in computational finishing of microbial genomes Read caption + In 2013, Los Alamos scientist Richard Sayre and his team...

  12. Organizing Committee

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformationJesseworkSURVEYI/O Streams for Large-scaleOrganizationAboutOrganizingOrganizing

  13. Powdery mildew control on pumpkin with organic and synthetic fungicides: 2009 field trial

    E-Print Network [OSTI]

    Janousek, Christopher N; Bay, Ian S.; Herche, Ryan W; Gubler, W D

    2009-01-01

    with an unsprayed control and water-only control (Table 1).Treatment Unsprayed control Water control Rally then Quintecwas 78.3 ± 6.9% in the water control and 80.0 ± 6.3% on

  14. Powdery mildew control on pumpkin with organic and synthetic fungicides: 2009 field trial

    E-Print Network [OSTI]

    Janousek, Christopher N; Bay, Ian S.; Herche, Ryan W; Gubler, W D

    2009-01-01

    2008) Efficacy of the biocontrol agents Bacillus subtilisperoxide, and the biocontrol agent, Strepyomyces lydicus

  15. Organic Superconductors

    SciTech Connect (OSTI)

    Charles Mielke

    2009-02-27

    Intense magnetic fields are an essential tool for understanding layered superconductors. Fundamental electronic properties of organic superconductors are revealed in intense (60 tesla) magnetic fields. Properties such as the topology of the Fermi surface and the nature of the superconducting order parameter are revealed. With modest maximum critical temperatures~13K the charge transfer salt organic superconductors prove to be incredibly valuable materials as their electronically clean nature and layered (highly anisotropic) structures yield insights to the high temperature superconductors. Observation of de Haas-van Alphen and Shubnikov-de Haas quantum oscillatory phenomena, magnetic field induced superconductivity and re-entrant superconductivity are some of the physical phenomena observed in the charge transfer organic superconductors. In this talk, I will discuss the nature of organic superconductors and give an overview of the generation of intense magnetic fields; from the 60 tesla millisecond duration to the extreme 1000 tesla microsecond pulsed magnetic fields.

  16. Biological Science courses BE 513 Molecuar and Celluar Biology

    E-Print Network [OSTI]

    Fang-Yen, Christopher

    Biological Science courses BE 513 Molecuar and Celluar Biology BE 555 Nanoscale Systems Biology. BIOM 501 Mechanisms of Disease and Therapeutic BIOM 600 Cell Biology BMB 508 Molecular Biophysics I BMB 509 Macromolecular Biophysics II BMB 567 Bioinorganic Chemistry BMB 590 Biological Physics BMB 614

  17. BACHELOR OF SCIENCE BIOLOGY ECOLOGY & EVOLUTIONARY BIOLOGY OPTION

    E-Print Network [OSTI]

    Kemp, Brian M.

    BACHELOR OF SCIENCE ­ BIOLOGY ECOLOGY & EVOLUTIONARY BIOLOGY OPTION A Bachelor of Science degree hours must be upper division coursework. A B.S. in Biology requires a minimum of 19 semester hours of core BIOLOGY courses (BIOLOGY 106, 107, 301, 372 and 405 or 403). An additional 21 semester hours

  18. Biology and Marine Biology Research Areas and Assistantship Application

    E-Print Network [OSTI]

    Olszewski Jr., Edward A.

    1 Biology and Marine Biology Research Areas and Assistantship Application Name: LAST FIRST MIDDLE and Marine Biology faculty members will accept graduate students to work in the general research areas listed Next Page Revised 3/08 850 #12;2 Biology and Marine Biology Statement of Interest Statement of Interest

  19. A threshold area ratio of organic to conventional agriculture causes recurrent pathogen outbreaks in organic agriculture

    E-Print Network [OSTI]

    Kolokolnikov, Theodore

    A threshold area ratio of organic to conventional agriculture causes recurrent pathogen outbreaks in organic agriculture S. Adl a, , D. Iron b , T. Kolokolnikov b a Department of Biology, Dalhousie 2011 Available online 21 March 2011 Keywords: Allodeposition Diffusive logistic equations Food security

  20. Integrated Biological Control

    SciTech Connect (OSTI)

    JOHNSON, A.R.

    2003-10-09

    Biological control is any activity taken to prevent, limit, clean up, or remediate potential environmental, health and safety, or workplace quality impacts from plants, animals, or microorganisms. At Hanford the principal emphasis of biological control is to prevent the transport of radioactive contamination by biological vectors (plants, animals, or microorganisms), and where necessary, control and clean up resulting contamination. Other aspects of biological control at Hanford include industrial weed control (e.g.; tumbleweeds), noxious weed control (invasive, non-native plant species), and pest control (undesirable animals such as rodents and stinging insects, and microorganisms such as molds that adversely affect the quality of the workplace environment). Biological control activities may be either preventive (a priori) or in response to existing contamination spread (a posteriori). Surveillance activities, including ground, vegetation, flying insect, and other surveys, and a priori control actions, such as herbicide spraying and placing biological barriers, are important in preventing radioactive contamination spread. If surveillance discovers that biological vectors have spread radioactive contamination, a posteriori control measures, such as fixing contamination, followed by cleanup and removal of the contamination to an approved disposal location are typical response functions. In some cases remediation following the contamination cleanup and removal is necessary. Biological control activities for industrial weeds, noxious weeds and pests have similar modes of prevention and response.

  1. Method and apparatus for removing heat from electronic devices using synthetic jets

    DOE Patents [OSTI]

    Sharma, Rajdeep; Weaver, Jr., Stanton Earl; Seeley, Charles Erklin; Arik, Mehmet; Icoz, Tunc; Wolfe, Jr., Charles Franklin; Utturkar, Yogen Vishwas

    2014-04-15

    An apparatus for removing heat comprises a heat sink having a cavity, and a synthetic jet stack comprising at least one synthetic jet mounted within the cavity. At least one rod and at least one engaging structure to provide a rigid positioning of the at least one synthetic jet with respect to the at least one rod. The synthetic jet comprises at least one orifice through which a fluid is ejected.

  2. Synthetic Metabolic Pathways for Bioconversion of Lignin Derivatives...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    compounds from biomass * Develop the genetic tools needed for bioengineering novel microbes * Develop a biological platform for production of fuels and chemicals from...

  3. The Intersection of Physics and Biology

    ScienceCinema (OSTI)

    Liphardt, Jan [University of California, Berkeley, California, United States

    2010-09-01

    In April 1953, Watson and Crick largely defined the program of 20th century biology: obtaining the blueprint of life encoded in the DNA. Fifty years later, in 2003, the sequencing of the human genome was completed. Like any major scientific breakthrough, the sequencing of the human genome raised many more questions than it answered. I'll brief you on some of the big open problems in cell and developmental biology, and I'll explain why approaches, tools, and ideas from the physical sciences are currently reshaping biological research. Super-resolution light microscopies are revealing the intricate spatial organization of cells, single-molecule methods show how molecular machines function, and new probes are clarifying the role of mechanical forces in cell and tissue function. At the same time, Physics stands to gain beautiful new problems in soft condensed matter, quantum mechanics, and non-equilibrium thermodynamics.

  4. Science Faculty Department of Biology

    E-Print Network [OSTI]

    Richner, Heinz

    Science Faculty Department of Biology Zoological Institute Community Ecology 1 December 2006 Hans-Sigrist-Symposium: Biological Invasions Hans-Sigrist-Stiftung 9.00 Prof. Dr. David M Richardson (Centre for Invasion Biology. Dr. Bruno Baur (Conservation Biology, Department of Integrative Biology, University of Basel

  5. Synthetic Lung Tumor Data Sets for Comparison of Volumetric Algorithms1

    E-Print Network [OSTI]

    Bernal, Javier

    Synthetic Lung Tumor Data Sets for Comparison of Volumetric Algorithms1 Adele P. Peskin of synthetic lung tumor data in which synthetic tumors of known volume are embedded in clinical lung computerized tomographic (CT) data in different background settings in the lung. Because the change

  6. A comparison between synthetic jets and continuous jets B.L. Smith, G.W. Swift

    E-Print Network [OSTI]

    Smith, Barton L.

    A comparison between synthetic jets and continuous jets B.L. Smith, G.W. Swift Abstract Experimental measurements and flow visualiza- tion of synthetic jets and continuous jets with matched Reynolds numbers are described. Although they have the same profile shape, synthetic jets are wider and slower than

  7. The acquisition of dangerous biological materials :

    SciTech Connect (OSTI)

    Aceto, Donato Gonzalo; Astuto-Gribble, Lisa M.; Gaudioso, Jennifer M.

    2007-11-01

    Numerous terrorist organizations have openly expressed interest in producing and deploying biological weapons. However, a limiting factor for many terrorists has been the acquisition of dangerous biological agents, as evidenced by the very few successful instances of biological weapons use compared to the number of documented hoaxes. Biological agents vary greatly in their ability to cause loss of life and economic damage. Some agents, if released properly, can kill many people and cause an extensive number of secondary infections; other agents will sicken only a small number of people for a short period of time. Consequently, several biological agents can potentially be used to perpetrate a bioterrorism attack but few are likely capable of causing a high consequence event. It is crucial, from a US national security perspective, to more deeply understand the likelihood that terrorist organizations can acquire the range of these agents. Few studies have attempted to comprehensively compile the technical information directly relevant to the acquisition of dangerous bacteria, viruses and toxins. In this report, technical fact sheets were assembled for 46 potentially dangerous biological agents. Much of the information was taken from various research sources which could ultimately and significantly expedite and improve bioterrorism threat assessments. By systematically examining a number of specific agent characteristics included in these fact sheets, it may be possible to detect, target, and implement measures to thwart future terrorist acquisition attempts. In addition, the information in these fact sheets may be used as a tool to help laboratories gain a rudimentary understanding of how attractive a method laboratory theft is relative to other potential acquisition modes.

  8. Synthetic aperture integration (SAI) algorithm for SAR imaging

    DOE Patents [OSTI]

    Chambers, David H; Mast, Jeffrey E; Paglieroni, David W; Beer, N. Reginald

    2013-07-09

    A method and system for detecting the presence of subsurface objects within a medium is provided. In some embodiments, the imaging and detection system operates in a multistatic mode to collect radar return signals generated by an array of transceiver antenna pairs that is positioned across the surface and that travels down the surface. The imaging and detection system pre-processes the return signal to suppress certain undesirable effects. The imaging and detection system then generates synthetic aperture radar images from real aperture radar images generated from the pre-processed return signal. The imaging and detection system then post-processes the synthetic aperture radar images to improve detection of subsurface objects. The imaging and detection system identifies peaks in the energy levels of the post-processed image frame, which indicates the presence of a subsurface object.

  9. Plant biology research and training for the 21st century

    SciTech Connect (OSTI)

    Kelly, K.

    1992-01-01

    The committee was assembled in response to a request from the National Science Foundation (NSF), the US Department of Agriculture (USDA), and the US Department of Energy (DoE). The leadership of these agencies asked the National Academy of Sciences through the National Research Council (NRC) to assess the status of plant-science research in the United States in light of the opportunities arising from advances inother areas of biology. NRC was asked to suggest ways of accelerating the application of these new biologic concepts and tools to research in plant science with the aim of enhancing the acquisition of new knowledge about plants. The charge to the committee was to examine the following: Organizations, departments, and institutions conducting plant biology research; human resources involved in plant biology research; graduate training programs in plant biology; federal, state, and private sources of support for plant-biology research; the role of industry in conducting and supporting plant-biology research; the international status of US plant-biology research; and the relationship of plant biology to leading-edge research in biology.

  10. Plant biology research and training for the 21st century

    SciTech Connect (OSTI)

    Kelly, K.

    1992-12-31

    The committee was assembled in response to a request from the National Science Foundation (NSF), the US Department of Agriculture (USDA), and the US Department of Energy (DoE). The leadership of these agencies asked the National Academy of Sciences through the National Research Council (NRC) to assess the status of plant-science research in the United States in light of the opportunities arising from advances inother areas of biology. NRC was asked to suggest ways of accelerating the application of these new biologic concepts and tools to research in plant science with the aim of enhancing the acquisition of new knowledge about plants. The charge to the committee was to examine the following: Organizations, departments, and institutions conducting plant biology research; human resources involved in plant biology research; graduate training programs in plant biology; federal, state, and private sources of support for plant-biology research; the role of industry in conducting and supporting plant-biology research; the international status of US plant-biology research; and the relationship of plant biology to leading-edge research in biology.

  11. Pentavalent Uranium Chemistry - Synthetic Pursuit Of A Rare Oxidation State

    SciTech Connect (OSTI)

    Graves, Christopher R; Kiplinger, Jaqueline L

    2009-01-01

    This feature article presents a comprehensive overview of pentavalent uranium systems in non-aqueous solution with a focus on the various synthetic avenues employed to access this unusual and very important oxidation state. Selected characterization data and theoretical aspects are also included. The purpose is to provide a perspective on this rapidly evolving field and identify new possibilities for future developments in pentavalent uranium chemistry.

  12. CO2 Removal using a Synthetic Analogue of Carbonic Anhydrase

    SciTech Connect (OSTI)

    Harry Cordatos

    2010-09-14

    Project attempts to develop a synthetic analogue for carbonic anhydrase and incorporate it in a membrane for separation of CO2 from coal power plant flue gas. Conference poster presents result of first 9 months of project progress including concept, basic system architecture and membrane properties target, results of molecular modeling for analogue - CO2 interaction, and next steps of testing analogue resistance to flue gas contaminants.

  13. Organization Chart

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformationJesseworkSURVEYI/O Streams for Large-scaleOrganization Chart Organization Charts

  14. Organizing Committee

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformationJesseworkSURVEYI/O Streams for Large-scaleOrganizationAbout EventsOrganizing

  15. Organizing Committee

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformationJesseworkSURVEYI/O Streams for Large-scaleOrganizationAboutOrganizing Committee

  16. Organizing Committee

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformationJesseworkSURVEYI/O Streams for Large-scaleOrganizationAboutOrganizing

  17. Extracting information from biological networks

    E-Print Network [OSTI]

    Chindelevitch, Leonid Alexandrovich

    2010-01-01

    Systems biology, the study of biological systems in a holistic manner, has been catalyzed by a dramatic improvement in experimental techniques, coupled with a constantly increasing availability of biological data. The ...

  18. COLLEGE OF ENGINEERING Biological Engineering

    E-Print Network [OSTI]

    Walter, M.Todd

    COLLEGE OF ENGINEERING Biological Engineering Undergraduate Class of 2013 Post-Graduation Report The Department Biological and Environmental Engineering (BEE) offers a bachelor degree program in Biological Engineering and a bachelor degree program in Environmental Engineering. Cornell Career Services surveys

  19. Method for producing and regenerating a synthetic CO[sub 2] acceptor

    DOE Patents [OSTI]

    Lancet, M. S.; Curran, G. P.; Gorin, E.

    1982-05-18

    A method is described for producing a synthetic CO[sub 2] acceptor by feeding a mixture of finely divided silica and at least one finely divided calcium compound selected from the group consisting of calcium oxide and calcium carbonate to a fluidized bed; operating the fluidized bed at suitable conditions to produce pellets of synthetic CO[sub 2] acceptor and recovering the pellets of synthetic CO[sub 2] acceptor from the fluidized bed. Optionally, spent synthetic CO[sub 2] acceptor can be charged to the fluidized bed to produce regenerated pellets of synthetic CO[sub 2] acceptor. 1 fig.

  20. Method for producing and regenerating a synthetic CO.sub.2 acceptor

    DOE Patents [OSTI]

    Lancet, Michael S. (Pittsburgh, PA); Curran, George P. (Pittsburgh, PA); Gorin, Everett (San Rafael, CA)

    1982-01-01

    A method for producing a synthetic CO.sub.2 acceptor by feeding a mixture of finely divided silica and at least one finely divided calcium compound selected from the group consisting of calcium oxide and calcium carbonate to a fluidized bed; operating the fluidized bed at suitable conditions to produce pellets of synthetic CO.sub.2 acceptor and recovering the pellets of synthetic CO.sub.2 acceptor from the fluidized bed. Optionally, spent synthetic CO.sub.2 acceptor can be charged to the fluidized bed to produce regenerated pellets of synthetic CO.sub.2 acceptor.

  1. Biological Conversion of Sugars To Hydrocarbons | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Biological Conversion of Sugars To Hydrocarbons Biological Conversion of Sugars To Hydrocarbons PDF explaining the biological process of bioenergy Biological Conversion of Sugars...

  2. Work with Biological Materials

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Work with Biological Materials Print Planning A complete Experiment Safety Sheet (ESS) is required before work can be done at the ALS. This ESS is either a part of the proposal...

  3. Vibrations, Quanta and Biology

    E-Print Network [OSTI]

    S. F. Huelga; M. B. Plenio

    2013-06-27

    Quantum biology is an emerging field of research that concerns itself with the experimental and theoretical exploration of non-trivial quantum phenomena in biological systems. In this tutorial overview we aim to bring out fundamental assumptions and questions in the field, identify basic design principles and develop a key underlying theme -- the dynamics of quantum dynamical networks in the presence of an environment and the fruitful interplay that the two may enter. At the hand of three biological phenomena whose understanding is held to require quantum mechanical processes, namely excitation and charge transfer in photosynthetic complexes, magneto-reception in birds and the olfactory sense, we demonstrate that this underlying theme encompasses them all, thus suggesting its wider relevance as an archetypical framework for quantum biology.

  4. Preparation of hydrophobic organic aeorgels

    DOE Patents [OSTI]

    Baumann, Theodore F. (Tracy, CA); Satcher, Jr., Joe H. (Patterson, CA); Gash, Alexander E. (Livermore, CA)

    2007-11-06

    Synthetic methods for the preparation of hydrophobic organics aerogels. One method involves the sol-gel polymerization of 1,3-dimethoxybenzene or 1,3,5-trimethoxybenzene with formaldehyde in non-aqueous solvents. Using a procedure analogous to the preparation of resorcinol-formaldehyde (RF) aerogels, this approach generates wet gels that can be dried using either supercritical solvent extraction to generate the new organic aerogels or air dried to produce an xerogel. Other methods involve the sol-gel polymerization of 1,3,5 trihydroxy benzene (phloroglucinol) or 1,3 dihydroxy benzene (resorcinol) and various aldehydes in non-aqueous solvents. These methods use a procedure analogous to the one-step base and two-step base/acid catalyzed polycondensation of phloroglucinol and formaldehyde, but the base catalyst used is triethylamine. These methods can be applied to a variety of other sol-gel precursors and solvent systems. These hydrophobic organics aerogels have numerous application potentials in the field of material absorbers and water-proof insulation.

  5. Preparation of hydrophobic organic aeorgels

    DOE Patents [OSTI]

    Baumann, Theodore F.; Satcher, Jr., Joe H.; Gash, Alexander E.

    2004-10-19

    Synthetic methods for the preparation of hydrophobic organics aerogels. One method involves the sol-gel polymerization of 1,3-dimethoxybenzene or 1,3,5-trimethoxybenzene with formaldehyde in non-aqueous solvents. Using a procedure analogous to the preparation of resorcinol-formaldehyde (RF) aerogels, this approach generates wet gels that can be dried using either supercritical solvent extraction to generate the new organic aerogels or air dried to produce an xerogel. Other methods involve the sol-gel polymerization of 1,3,5 trihydroxy benzene (phloroglucinol) or 1,3 dihydroxy benzene (resorcinol) and various aldehydes in non-aqueous solvents. These methods use a procedure analogous to the one-step base and two-step base/acid catalyzed polycondensation of phloroglucinol and formaldehyde, but the base catalyst used is triethylamine. These methods can be applied to a variety of other sol-gel precursors and solvent systems. These hydrophobic organics aerogels have numerous application potentials in the field of material absorbers and water-proof insulation.

  6. Guidelines to improve airport preparedness against chemical and biological terrorism.

    SciTech Connect (OSTI)

    Edwards, Donna M.; Price, Phillip N. (Lawrence Berkeley National Laboratory, Berkeley, CA); Gordon, Susanna P.; Gadgil, Ashok (Lawrence Berkeley National Laboratory, Berkeley, CA)

    2005-05-01

    Guidelines to Improve Airport Preparedness Against Chemical and Biological Terrorism is a 100-page document that makes concrete recommendations on improving security and assessing vulnerable areas and helps its readers understand the nature of chemical and biological attacks. The report has been turned over to Airports Council International (ACI) and the American Association of Airport Executives (AAAE), two organizations that together represent the interests of thousands of airport personnel and facilities in the U.S. and around the world.

  7. Biology Mathematics Connection Program Integrating Mathematics and Biology Program

    E-Print Network [OSTI]

    Biology Mathematics Connection Program Integrating Mathematics and Biology Program BMC pioneered a series of instructional modules for use in high school mathematics and biology classrooms to highlight the interconnections between the mathematical and biological sciences. IMB follows up by developing the BMC modules

  8. Marine Biology Is Marine Biology right for me?

    E-Print Network [OSTI]

    Martin, Ralph R.

    Marine Biology Is Marine Biology right for me? If you have an interest in learning about life in the sea then Marine Biology may be a good option for you. You will need good time management skills a marine biology degree are wide-ranging and provide a good basis for employment in almost any sector

  9. Biology & Biomedical Sciences ACADEMIC PROGRAM

    E-Print Network [OSTI]

    Gereau, Robert W. IV

    Biology & Biomedical Sciences ACADEMIC PROGRAM GUIDELINES Programs in Cell & Molecular Biology Molecular Microbiology & Microbial Pathogenesis Overview of the Programs in Cell and Molecular Biology Graduate training in Cell and Molecular Biology at Washington University is offered by the Programs in Cell

  10. POSITION ANNOUNCEMENT Insect Molecular Biology

    E-Print Network [OSTI]

    Ishida, Yuko

    POSITION ANNOUNCEMENT Insect Molecular Biology 03/21/2014 POSITION: Research Associate LOCATION in entomology, biochemistry, molecular biology and/or toxicology; extensive research experience in entomology, biochemistry, cell biology and/or molecular biology; excellent organizational, and written and interpersonal

  11. Biological Air Emissions Control

    Office of Energy Efficiency and Renewable Energy (EERE)

    Air quality standards are becoming more stringent for the U.S. wood products industry. Emissions of volatile organic compounds (VOCs) and hazardous air pollutants (HAPs) (including methanol,...

  12. Organic and Printed Electronics for Biological Microfluidic Applications

    E-Print Network [OSTI]

    Jagannathan, Lakshmi

    2012-01-01

    provide contamination and leakage free valves (robustness),the robustness and leakage of closed valves. Integrating thefor the valves. Finally, pressure and leakage tests will

  13. Concentration and separation of biological organisms by ultrafiltration and dielectrophoresis

    DOE Patents [OSTI]

    Simmons, Blake A. (San Francisco, CA); Hill, Vincent R. (Decatur, GA); Fintschenko, Yolanda (Livermore, CA); Cummings, Eric B. (Livermore, CA)

    2010-10-12

    Disclosed is a method for monitoring sources of public water supply for a variety of pathogens by using a combination of ultrafiltration techniques together dielectrophoretic separation techniques. Because water-borne pathogens, whether present due to "natural" contamination or intentional introduction, would likely be present in drinking water at low concentrations when samples are collected for monitoring or outbreak investigations, an approach is needed to quickly and efficiently concentrate and separate particles such as viruses, bacteria, and parasites in large volumes of water (e.g., 100 L or more) while simultaneously reducing the sample volume to levels sufficient for detecting low concentrations of microbes (e.g., <10 mL). The technique is also designed to screen the separated microbes based on specific conductivity and size.

  14. Structural and Computational Studies of Small Organic and Biological Molecules 

    E-Print Network [OSTI]

    Lozano-Casal, Patricia

    2006-01-01

    Over the last three decades high-pressure X-ray diffraction techniques have been widely utilised to perform structural studies in many areas of research. For example, physicists make use of these experimental techniques ...

  15. Organic and Printed Electronics for Biological Microfluidic Applications

    E-Print Network [OSTI]

    Jagannathan, Lakshmi

    2012-01-01

    and Q. Zhang, “Printed electronics for low-cost electronicUltra-Low-Cost Printed Electronics,” Ph.D. dissertation,capability of printed electronics to make important aspects

  16. Organic and Printed Electronics for Biological Microfluidic Applications

    E-Print Network [OSTI]

    Jagannathan, Lakshmi

    2012-01-01

    Journal of Microelectromechanical Systems, vol. 10, no. 2,Journal of Microelectromechanical Systems, vol. 12, no. 3,nanoparticle microelectromechanical systems,” Journal of

  17. Organic and Printed Electronics for Biological Microfluidic Applications

    E-Print Network [OSTI]

    Jagannathan, Lakshmi

    2012-01-01

    micropump,” Journal of Microelectromechanical Systems, vol.principles,” Journal of Microelectromechanical Systems, vol.nanoparticle microelectromechanical systems,” Journal of

  18. Organic and Printed Electronics for Biological Microfluidic Applications

    E-Print Network [OSTI]

    Jagannathan, Lakshmi

    2012-01-01

    convective heat transfer, and radiation. Conduction is heatheat transfer is when heat is transported by a fluid motion. Radiation

  19. Nanoparticle Formation of Organic Compounds With Retained Biological Activity

    E-Print Network [OSTI]

    Zare, Richard N.

    .58C and 75.8 bar). Supercritical carbon dioxide (SC-CO2) is also nonflammable and inexpensive.6 to be formed as well as control of the size distribution.7 Moreover, SC-CO2 antisolvent precipitation is highly of supercritical carbon dioxide as an antisolvent for meeting this need for two model drug systems, quercetin

  20. Apodized RFI filtering of synthetic aperture radar images.

    SciTech Connect (OSTI)

    Doerry, Armin Walter

    2014-02-01

    Fine resolution Synthetic Aperture Radar (SAR) systems necessarily require wide bandwidths that often overlap spectrum utilized by other wireless services. These other emitters pose a source of Radio Frequency Interference (RFI) to the SAR echo signals that degrades SAR image quality. Filtering, or excising, the offending spectral contaminants will mitigate the interference, but at a cost of often degrading the SAR image in other ways, notably by raising offensive sidelobe levels. This report proposes borrowing an idea from nonlinear sidelobe apodization techniques to suppress interference without the attendant increase in sidelobe levels. The simple post-processing technique is termed Apodized RFI Filtering (ARF).

  1. Fate of Mercury in Synthetic Gypsum Used for Wallboard Production

    SciTech Connect (OSTI)

    Jessica Sanderson

    2007-12-31

    This report presents and discusses results from the project 'Fate of Mercury in Synthetic Gypsum Used for Wallboard Production', performed at five different full-scale commercial wallboard plants. Synthetic gypsum produced by wet flue gas desulfurization (FGD) systems on coal-fired power plants is commonly used in the manufacture of wallboard. This practice has long benefited the environment by recycling the FGD gypsum byproduct, which is becoming available in increasing quantities, decreasing the need to landfill this material, and increasing the sustainable design of the wallboard product. However, new concerns have arisen as recent mercury control strategies involve the capture of mercury in FGD systems. The objective of this study has been to determine whether any mercury is released into the atmosphere at wallboard manufacturing plants when the synthetic gypsum material is used as a feedstock for wallboard production. The project has been co-funded by the U.S. DOE National Energy Technology Laboratory (Cooperative Agreement DE-FC26-04NT42080), USG Corporation, and EPRI. USG Corporation is the prime contractor, and URS Group is a subcontractor. The project scope included seven discrete tasks, each including a test conducted at various USG wallboard plants using synthetic gypsum from different wet FGD systems. The project was originally composed of five tasks, which were to include (1) a base-case test, then variations representing differing power plant: (2) emissions control configurations, (3) treatment of fine gypsum particles, (4) coal types, and (5) FGD reagent types. However, Task 5,could not be conducted as planned and instead was conducted at conditions similar to Task 3. Subsequently an opportunity arose to test gypsum produced from the Task 5 FGD system, but with an additive expected to impact the stability of mercury, so Task 6 was added to the project. Finally, Task 7 was added to evaluate synthetic gypsum produced at a power plant from an additional coal type. In the project, process stacks in the wallboard plant were sampled using the Ontario Hydro method. In every task, the stack locations sampled included a gypsum dryer and a gypsum calciner. In Tasks 1 and 4 through 7, the stack of the dryer for the wet wallboard product was also tested. Also at each site, in-stream process samples were collected and analyzed for mercury concentration before and after each significant step in wallboard production. These results and process data were used to construct mercury mass balances across the wallboard plants. The results from the project showed a wide range of percentage mercury losses from the synthetic gypsum feedstocks as measured by the Ontario Hydro method at the process stacks, ranging from 2% to 55% of the mercury in the gypsum feedstock. For the tasks exceeding 10% mercury loss across the wallboard plant, most of the loss occurred across the gypsum calciner. When total wallboard emissions remained below 10%, the primary emission location varied with a much less pronounced difference in emission between the gypsum dryer, calciner and board dryer. For all seven tasks, the majority of the mercury emissions were measured to be in the elemental form (Hg{sup 0}). Overall, the measured mercury loss mass rates ranged from 0.01 to 0.17 grams of mercury per dry ton of synthetic gypsum processed, or 0.01 to 0.4 pounds of mercury released per million square feet of wallboard produced from synthetic gypsum. The Coal Combustion Product Production and Use Survey from the American Coal Ash Association (ACAA) indicate that 7,579,187 short tons of synthetic gypsum were used for wallboard production in 2006. Extrapolating the results of this study to the ACAA industry usage rate, we estimate that mercury releases from wallboard production plants in 2006 ranged between 150 to 3000 pounds for the entire U.S. wallboard industry. With only seven sets of wallboard plant measurements, it is difficult to draw firm conclusions about what variables impact the mercury loss percentages across the wallboard plants. One significant o

  2. Phase correction system for automatic focusing of synthetic aperture radar

    DOE Patents [OSTI]

    Eichel, Paul H. (Albuquerque, NM); Ghiglia, Dennis C. (Placitas, NM); Jakowatz, Jr., Charles V. (Albuquerque, NM)

    1990-01-01

    A phase gradient autofocus system for use in synthetic aperture imaging accurately compensates for arbitrary phase errors in each imaged frame by locating highlighted areas and determining the phase disturbance or image spread associated with each of these highlight areas. An estimate of the image spread for each highlighted area in a line in the case of one dimensional processing or in a sector, in the case of two-dimensional processing, is determined. The phase error is determined using phase gradient processing. The phase error is then removed from the uncorrected image and the process is iteratively performed to substantially eliminate phase errors which can degrade the image.

  3. Synthetic fuel concept to steal CO2 from air

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorking With LivermoreSustainable Land LabEnergyNationalScienceSynthetic fuel

  4. Synthetic limbs: Rasmussen's lifelong quest | Princeton Plasma Physics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorking With LivermoreSustainable Land LabEnergyNationalScienceSynthetic

  5. Synthetic muscle developed with PPPL scientists' help launches | Princeton

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorking With LivermoreSustainable Land LabEnergyNationalScienceSyntheticPlasma

  6. Sandia National Laboratories: Synthetic Aperture Radar (SAR) Imagery

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservation ofAlbuquerque AlbuquerqueCybernetics:Defense Systems &Vision,Synthetic

  7. Systems Biology Knowledgebase for a New Era in Biology A Genomics:GTL Report from the May 2008 Workshop

    SciTech Connect (OSTI)

    Gregurick, S.; Fredrickson, J. K.; Stevens, R.

    2009-03-01

    Biology has entered a systems-science era with the goal to establish a predictive understanding of the mechanisms of cellular function and the interactions of biological systems with their environment and with each other. Vast amounts of data on the composition, physiology, and function of complex biological systems and their natural environments are emerging from new analytical technologies. Effectively exploiting these data requires developing a new generation of capabilities for analyzing and managing the information. By revealing the core principles and processes conserved in collective genomes across all biology and by enabling insights into the interplay between an organism's genotype and its environment, systems biology will allow scientific breakthroughs in our ability to project behaviors of natural systems and to manipulate and engineer managed systems. These breakthroughs will benefit Department of Energy (DOE) missions in energy security, climate protection, and environmental remediation.

  8. Complex biological and bio-inspired systems

    SciTech Connect (OSTI)

    Ecke, Robert E [Los Alamos National Laboratory

    2009-01-01

    The understanding and characterization ofthe fundamental processes of the function of biological systems underpins many of the important challenges facing American society, from the pathology of infectious disease and the efficacy ofvaccines, to the development of materials that mimic biological functionality and deliver exceptional and novel structural and dynamic properties. These problems are fundamentally complex, involving many interacting components and poorly understood bio-chemical kinetics. We use the basic science of statistical physics, kinetic theory, cellular bio-chemistry, soft-matter physics, and information science to develop cell level models and explore the use ofbiomimetic materials. This project seeks to determine how cell level processes, such as response to mechanical stresses, chemical constituents and related gradients, and other cell signaling mechanisms, integrate and combine to create a functioning organism. The research focuses on the basic physical processes that take place at different levels ofthe biological organism: the basic role of molecular and chemical interactions are investigated, the dynamics of the DNA-molecule and its phylogenetic role are examined and the regulatory networks of complex biochemical processes are modeled. These efforts may lead to early warning algorithms ofpathogen outbreaks, new bio-sensors to detect hazards from pathomic viruses to chemical contaminants. Other potential applications include the development of efficient bio-fuel alternative-energy processes and the exploration ofnovel materials for energy usages. Finally, we use the notion of 'coarse-graining,' which is a method for averaging over less important degrees of freedom to develop computational models to predict cell function and systems-level response to disease, chemical stress, or biological pathomic agents. This project supports Energy Security, Threat Reduction, and the missions of the DOE Office of Science through its efforts to accurately model biological systems at the molecular and cellular level. The project's impact encompasses applications to biofuels, to novel sensors and to materials with broad use for energy or threat reduction. The broad, interdisciplinary approach of CNLS offers the unparalleled strength of combining science backgrounds and expertise -a unique and important asset in attacking the complex science of biological organisms. This approach also allows crossfertilization, with concepts and techniques transferring across field boundaries.

  9. Organizing Committee

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformationJesseworkSURVEYI/O Streams for Large-scaleOrganizationAbout Events

  10. Organizing Committee

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformationJesseworkSURVEYI/O Streams for Large-scaleOrganizationAbout

  11. Chemistry & Biology Brief Communication

    E-Print Network [OSTI]

    Cheng, Jianjun

    inorganic mercury is found in water, soil, food sources, and a broad range of environments have been developed based on small organic molecules (Yoon et al., 1997; Guo et al., 2004; Caballero et et al., 2008). Despite the progress of mercury detection in organic solvents, there remains a need

  12. Biological effectiveness of neutrons: Research needs

    SciTech Connect (OSTI)

    Casarett, G.W.; Braby, L.A.; Broerse, J.J.; Elkind, M.M.; Goodhead, D.T.; Oleinick, N.L.

    1994-02-01

    The goal of this report was to provide a conceptual plan for a research program that would provide a basis for determining more precisely the biological effectiveness of neutron radiation with emphasis on endpoints relevant to the protection of human health. This report presents the findings of the experts for seven particular categories of scientific information on neutron biological effectiveness. Chapter 2 examines the radiobiological mechanisms underlying the assumptions used to estimate human risk from neutrons and other radiations. Chapter 3 discusses the qualitative and quantitative models used to organize and evaluate experimental observations and to provide extrapolations where direct observations cannot be made. Chapter 4 discusses the physical principles governing the interaction of radiation with biological systems and the importance of accurate dosimetry in evaluating radiation risk and reducing the uncertainty in the biological data. Chapter 5 deals with the chemical and molecular changes underlying cellular responses and the LET dependence of these changes. Chapter 6, in turn, discusses those cellular and genetic changes which lead to mutation or neoplastic transformation. Chapters 7 and 8 examine deterministic and stochastic effects, respectively, and the data required for the prediction of such effects at different organizational levels and for the extrapolation from experimental results in animals to risks for man. Gaps and uncertainties in this data are examined relative to data required for establishing radiation protection standards for neutrons and procedures for the effective and safe use of neutron and other high-LET radiation therapy.

  13. A single crystalline porphyrinic titanium metal–organic framework

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Yuan, Shuai; Liu, Tian -Fu; Feng, Dawei; Tian, Jian; Wang, Kecheng; Qin, Junsheng; Zhang, Qiang; Chen, Ying -Pin; Bosch, Mathieu; Zou, Lanfang; et al

    2015-04-28

    We successfully assembled the photocatalytic titanium-oxo cluster and photosensitizing porphyrinic linker into a metal–organic framework (MOF), namely PCN-22. A preformed titanium-oxo carboxylate cluster is adopted as the starting material to judiciously control the MOF growth process to afford single crystals. This synthetic method is useful to obtain highly crystalline titanium MOFs, which has been a daunting challenge in this field. Moreover, PCN-22 demonstrated permanent porosity and photocatalytic activities toward alcohol oxidation.

  14. Fish Biology Introduction

    E-Print Network [OSTI]

    Jochem, Frank J.

    Lab 10: Fish Biology Introduction The effective management of fish populations requires knowledge of the growth rate of the fish. This requires determination of the age of fish to develop a relationship between the size and age of fish. For an inventory, this information provides insights to evaluate the potential

  15. Chemistry & Biology Brief Communication

    E-Print Network [OSTI]

    Herschlag, Dan

    . In each of these cases the native hydroxyl group interacts with a purine exocy- clic amine. Our resultsChemistry & Biology Brief Communication 20 -Fluoro Substituents Can Mimic Native 20 -Hydroxyls signature for tertiary interac- tions between 20 -hydroxyl groups and exocyclic amino groups within RNA

  16. Chemistry & Biology Perspective

    E-Print Network [OSTI]

    Williams, Loren

    Chemistry & Biology Perspective The Origin of RNA and ``My Grandfather's Axe'' Nicholas V. Hud,1 *Correspondence: hud@gatech.edu http://dx.doi.org/10.1016/j.chembiol.2013.03.012 The origin of RNA is one

  17. Chemistry and Chemical Biology

    E-Print Network [OSTI]

    Linhardt, Robert J.

    /polymeric materials for electronics or energy storage, and polyelectrolyte membranes for fuel cell applications. http projects in emerging fields of science and technology that lie at the intersection between chemistry Biology at Rensselaer invites applications from students interested in pursuing a Ph.D. degree

  18. Molecular Interactions of Plutonium(VI) with Synthetic Manganese-Substituted Goethite

    E-Print Network [OSTI]

    Hu, Yung-Jin

    2011-01-01

    VI) with the Iron Oxide Goethite, University of California,Values for Synthetic Goethite and Pyrolusite" submitted tothe two Mn-substituted goethite minerals used in this study.

  19. Molecular Interactions of Plutonium(VI) with Synthetic Manganese-Substituted Goethite

    E-Print Network [OSTI]

    Hu, Yung-Jin

    2011-01-01

    E. , Thesis, Reactions of Plutonium(VI) with the Iron Oxideof Uranium, Neptunium, Plutonium, Americium and Technetium;Molecular Interactions of Plutonium(VI) with Synthetic

  20. Monitoring Biological Activity at Geothermal Power Plants

    SciTech Connect (OSTI)

    Peter Pryfogle

    2005-09-01

    The economic impact of microbial growth in geothermal power plants has been estimated to be as high as $500,000 annually for a 100 MWe plant. Many methods are available to monitor biological activity at these facilities; however, very few plants have any on-line monitoring program in place. Metal coupon, selective culturing (MPN), total organic carbon (TOC), adenosine triphosphate (ATP), respirometry, phospholipid fatty acid (PLFA), and denaturing gradient gel electrophoresis (DGGE) characterizations have been conducted using water samples collected from geothermal plants located in California and Utah. In addition, the on-line performance of a commercial electrochemical monitor, the BIoGEORGE?, has been evaluated during extended deployments at geothermal facilities. This report provides a review of these techniques, presents data on their application from laboratory and field studies, and discusses their value in characterizing and monitoring biological activities at geothermal power plants.

  1. Fate of Mercury in Synthetic Gypsum Used for Wallboard Production

    SciTech Connect (OSTI)

    Jessica Sanderson; Gary M. Blythe; Mandi Richardson

    2006-12-01

    This report presents and discusses results from Task 6 of the study 'Fate of Mercury in Synthetic Gypsum Used for Wallboard Production,' performed at a full-scale commercial wallboard plant. Synthetic gypsum produced by wet flue gas desulfurization (FGD) systems on coal-fired power plants is commonly used in the manufacture of wallboard. This practice has long benefited the environment by recycling the FGD gypsum byproduct, which is becoming available in increasing quantities, decreasing the need to landfill this material, and increasing the sustainable design of the wallboard product. However, new concerns have arisen as recent mercury control strategies involve the capture of mercury in FGD systems. The objective of this study is to determine whether any mercury is released into the atmosphere when the synthetic gypsum material is used as a feedstock for wallboard production. The project is being co-funded by the U.S. DOE National Energy Technology Laboratory (Cooperative Agreement DE-FC26-04NT42080), USG Corporation, and EPRI. USG Corporation is the prime contractor, and URS Group is a subcontractor. The project scope now includes six discrete tasks, each conducted at various USG wallboard plants using synthetic gypsum from different FGD systems. The project was originally composed of five tasks, which were to include (1) a baseline test, then variations representing differing power plant: (2) emissions control configurations, (3) treatment of fine gypsum particles, (4) coal types, and (5) FGD reagent types. However, Task 5, which was to include testing with an alternate FGD reagent, could not be conducted as planned. Instead, Task 5 was conducted at conditions similar to Task 3, although with gypsum from an alternate FGD system. Subsequent to conducting Task 5 under these revised conditions, an opportunity arose to test gypsum produced at the same FGD system, but with an additive (Degussa Corporation's TMT-15) being used in the FGD system. TMT-15 was expected to impact the stability of mercury in synthetic gypsum used to produce wallboard, so Task 6 was added to the project to test this theory. In this project, process stacks in the wallboard plant have been sampled using the Ontario Hydro method. For every task, the stack locations sampled have included a dryer for the wet gypsum as it enters the plant and a gypsum calciner. For Tasks 1, 4, 5 and 6, the stack of the dryer for the wet wallboard product was also tested. Also at each site, in-stream process samples were collected and analyzed for mercury concentration before and after each significant step in wallboard production. The Ontario Hydro results, process sample mercury concentration data, and process data were used to construct mercury mass balances across the wallboard plants. Task 6 was conducted at a wallboard plant processing synthetic gypsum from a power plant that fires Eastern bituminous coal. The power plant has a single-loop, open spray tower limestone forced oxidation FGD system, with the forced oxidation conducted in the reaction tank integral with the FGD absorber. The FGD system has gypsum fines blow down as part of the dewatering step. The power plant is equipped with a selective catalytic reduction (SCR) system for NOX emissions control, and the SCR was in service during the time period the gypsum tested was produced. Also, as mentioned above, Degussa additive TMT-15 was being added to the FGD system when this gypsum was produced. The results of the Task 6 stack testing, as measured by the Ontario Hydro method, detected that an average of 55% of the incoming mercury was emitted during wallboard production. These losses were distributed as about 4% across the dryer mill, 6% across the board dryer kiln, and 45% across the kettle calciner. Emissions were similar to what Task 5 results showed on a percentage basis, but about 30% lower on a mass basis. The same power plant FGD system produced the synthetic gypsum used in Task 5 (with no use of TMT-15) and in Task 6 (with TMT-15 added to the FGD system). The lower emissions on a mass basis appeared

  2. Inorganic Metal Oxide/Organic Polymer Nanocomposites And Method Thereof

    DOE Patents [OSTI]

    Gash, Alexander E. (Livermore, CA); Satcher, Joe H. (Patterson, CA); Simpson, Randy (Livermore, CA)

    2004-11-16

    A synthetic method for preparation of hybrid inorganic/organic energetic nanocomposites is disclosed herein. The method employs the use of stable metal in organic salts and organic solvents as well as an organic polymer with good solubility in the solvent system to produce novel nanocomposite energetic materials. In addition, fuel metal powders (particularly those that are oxophilic) can be incorporated into composition. This material has been characterized by thermal methods, energy-filtered transmission electron microscopy (EFTEM), N.sub.2 adsoprtion/desorption methods, and Fourier-Transform (FT-IR) spectroscopy. According to these characterization methods the organic polymer phase fills the nanopores of the material, providing superb mixing of the component phases in the energetic nanocomposite.

  3. Biological Engineering 2014-2015 BIOLOGICAL ENGINEERING PROGRAM PROGRESS FORM

    E-Print Network [OSTI]

    Walter, M.Todd

    Biological Engineering 2014-2015 8 BIOLOGICAL ENGINEERING PROGRAM PROGRESS FORM Applies to students Calculus for Engineers I* MATH 1910 (4) ______ _____ _____ Calculus for Engineers II* MATH 1920 (4) ______ _____ _____ Engineering Math* (Differential Equations) MATH 2930 (4) ______ _____ _____ Engineering Math* (Linear Algebra

  4. Biology 472 Spring 2009 Biology of Amphibians and Reptiles

    E-Print Network [OSTI]

    Jackson, Kate

    Biology 472 Spring 2009 1 Biology of Amphibians and Reptiles Dr. Kate Jackson Office: Science 200 E Encyclopedia of Reptiles and Amphibians. Oxford University Press. (2) Stebbins, R. and R. T. Peterson. 2003 of assorted herps (from labs). #12;Biology 472 Spring 2009 2 · ...know how to access primary sources

  5. BACHELOR OF SCIENCE BIOLOGY GENERAL OPTION

    E-Print Network [OSTI]

    Kemp, Brian M.

    * OR 201 Physics 4 hrs. PHYSICS 102* OR 202 Physics 4 hrs. General Biology Option Requirements: CellBACHELOR OF SCIENCE ­ BIOLOGY GENERAL OPTION A Bachelor of Science degree from Washington State Requirements: Grade BIOLOGY 106 General Biology 4 hrs. BIOLOGY 107 General Biology 4 hrs. BIOLOGY 301 General

  6. Introduction to ``Understanding the Ocean's biological pump: Results from VERTIGO''

    E-Print Network [OSTI]

    Buesseler, Ken

    declines dramatically with depth, such that the water at 1000 m is isolated from the atmosphere for many and efficiency of this so called biological pump is important in determining the oceanographic distribution of organisms, for the supply of energy to subsurface heterotrophic ecosystems, in setting the vertical

  7. Synthetic Spectra from PIC Simulations of Relativistic Collisionless Shocks

    E-Print Network [OSTI]

    Sironi, Lorenzo

    2009-01-01

    We extract synthetic photon spectra from first-principles particle-in-cell simulations of relativistic shocks propagating in unmagnetized pair plasmas. The two basic ingredients for the radiation, namely accelerated particles and magnetic fields, are produced self-consistently as part of the shock evolution. We use the method of Hededal & Nordlund (2005) and compute the photon spectrum via Fourier transform of the electric far-field from a large number of particles, sampled directly from the simulation. We find that the spectrum from relativistic collisionless shocks is entirely consistent with synchrotron radiation in the magnetic fields generated by Weibel instability. We can recover the so-called "jitter'' regime only if we artificially reduce the strength of the electromagnetic fields, such that the wiggler parameter K = qB lambda/mc^2 becomes much smaller than unity ("B" and "lambda" are the strength and scale of the magnetic turbulence, respectively). These findings may place constraints on the orig...

  8. X-ray Moiré deflectometry using synthetic reference images

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Stutman, Dan; Valdivia, Maria Pia; Finkenthal, Michael

    2015-06-25

    Moiré fringe deflectometry with grating interferometers is a technique that enables refraction-based x-ray imaging using a single exposure of an object. To obtain the refraction image, the method requires a reference fringe pattern (without the object). Our study shows that, in order to avoid artifacts, the reference pattern must be exactly matched in phase with the object fringe pattern. In experiments, however, it is difficult to produce a perfectly matched reference pattern due to unavoidable interferometer drifts. We present a simple method to obtain matched reference patterns using a phase-scan procedure to generate synthetic Moiré images. As a result, themore »method will enable deflectometric diagnostics of transient phenomena such as laser-produced plasmas and could improve the sensitivity and accuracy of medical phase-contrast imaging.« less

  9. Time-frequency analysis of synthetic aperture radar signals

    SciTech Connect (OSTI)

    Johnston, B.

    1996-08-01

    Synthetic aperture radar (SAR) has become an important tool for remote sensing of the environment. SAR is a set of digital signal processing algorithms that are used to focus the signal returned to the radar because radar systems in themselves cannot produce the high resolution images required in remote sensing applications. To reconstruct an image, several parameters must be estimated and the quality of output image depends on the degree of accuracy of these parameters. In this thesis, we derive the fundamental SAR algorithms and concentrate on the estimation of one of its critical parameters. We show that the common technique for estimating this particular parameter can sometimes lead to erroneous results and reduced quality images. We also employ time-frequency analysis techniques to examine variations in the radar signals caused by platform motion and show how these results can be used to improve output image quality.

  10. Synthetic thrombus model for in vitro studies of laser thrombolysis

    SciTech Connect (OSTI)

    Hermes, R.E.; Trajkovska, K.

    1998-07-01

    Laser thrombolysis is the controlled ablation of a thrombus (blood clot) blockage in a living arterial system. Theoretical modeling of the interaction of laser light with thrombi relies on the ability to perform in vitro experiments with well characterized surrogate materials. A synthetic thrombus formulation may offer more accurate results when compared to in vivo clinical experiments. The authors describe the development of new surrogate materials based on formulations incorporating chick egg, guar gum, modified food starch, and a laser light absorbing dye. The sound speed and physical consistency of the materials were very close to porcine (arterial) and human (venous) thrombi. Photographic and videotape recordings of pulsed dye laser ablation experiments under various experimental conditions were used to evaluate the new material as compared to in vitro tests with human (venous) thrombus. The characteristics of ablation and mass removal were similar to that of real thrombi, and therefore provide a more realistic model for in vitro laser thrombolysis when compared to gelatin.

  11. Characterization of phase evolution during lead immobilization by synthetic hydroxyapatite

    SciTech Connect (OSTI)

    Mavropoulos, Elena [CBPF, Rio de Janeiro (Brazil); Rocha, Nilce C.C. [IQ/UFRJ, Rio de Janeiro (Brazil); Moreira, Josino C. [ENSP/FIOCRUZ, Rio de Janeiro (Brazil); Rossi, Alexandre M. [CBPF, Rio de Janeiro (Brazil); Soares, Gloria A. [Metallurgical and Materials Engineering Department, Federal University of Rio de Janeiro, P.O. Box 68505, Rio de Janeiro, 21941-972, RJ (Brazil)]. E-mail: Gloria@ufrj.br

    2004-09-15

    Immobilization of toxic metals by calcium phosphates is a promising technology for treating contaminated soil, water and wastes. A detailed study on the mechanisms of lead immobilization by hydroxyapatite has been carried out using scanning electron microscopy (SEM), transmission electron microscopy (TEM) and X-ray diffraction (XRD). For this, synthetic hydroxyapatite powder were submitted to a sorption process through exposure to an aqueous solution containing 917 mg L{sup -1} of lead for times that varied from 3 min to 54 h. The results obtained reinforce the hypothesis that hydroxypyromorphite formation is the end of a kinetic process in which the hydroxyapatite crystals are continuously dissolved and recrystallized in order to form more stable structures with higher lead content. Consequently, the use of calcium phosphates to immobilize lead ions seems to be technically viable.

  12. Modular architecture in biological networks

    E-Print Network [OSTI]

    Ramachandran, Gopal (Gopal Sebastian)

    2007-01-01

    In the past decade, biology has been revolutionized by an explosion in the availability of data. Translating this new wealth of information into meaningful biological insights and clinical breakthroughs will require a ...

  13. Experiment design for systems biology

    E-Print Network [OSTI]

    Apgar, Joshua Farley

    2009-01-01

    Mechanism-based chemical kinetic models are increasingly being used to describe biological signaling. Such models serve to encapsulate current understanding of pathways and to enable insight into complex biological processes. ...

  14. Systems Biology | More Science | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ORNL brings together multidisciplinary expertise and special facilities in genomics, computational biology, plant sciences, microbiology, microbial ecology, biophysics,...

  15. Systems Biology | Clean Energy | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ORNL brings together multidisciplinary expertise and special facilities in genomics, computational biology, plant sciences, microbiology, microbial ecology, biophysics,...

  16. Environmental Biology | Clean Energy | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    microbiology, biogeochemistry, molecular biology, molecular dynamics, bioinformatics, genomics, neutron science, chemistry, and computing-and spans multiple scales, from the...

  17. Abengoa Mojave Final Biological Opinion

    Broader source: Energy.gov [DOE]

    Biological Opinion on Mojave Solar, LLC's Mojave Solar Project, San Bernardino County, California (8-8-11-F-3)

  18. 2/Donald M. Knutson-Abstract: Biological and chemical control agents for

    E-Print Network [OSTI]

    2/Donald M. Knutson- Abstract: Biological and chemical control agents for control of dwarfZinclrocarpon g i l i i i , dwarf mistletoe, biological control, chemical control. INTRODUCTION Forest managers organisms and with chemicals that can be applied to infected trees and which selectively kill the dwarf

  19. Biological particle identification apparatus

    DOE Patents [OSTI]

    Salzman, Gary C. (Los Alamos, NM); Gregg, Charles T. (Los Alamos, NM); Grace, W. Kevin (Los Alamos, NM); Hiebert, Richard D. (Los Alamos, NM)

    1989-01-01

    An apparatus and method for making multiparameter light scattering measurements from suspensions of biological particles is described. Fourteen of the sixteen Mueller matrix elements describing the particles under investigation can be substantially individually determined as a function of scattering angle and probing radiations wavelength, eight elements simultaneously for each of two apparatus configurations using an apparatus which incluees, in its simplest form, two polarization modulators each operating at a chosen frequency, one polarizer, a source of monochromatic electromagnetic radiation, a detector sensitive to the wavelength of radiation employed, eight phase-sensitive detectors, and appropriate electronics. A database of known biological particle suspensions can be assembled, and unknown samples can be quickly identified once measurements are performed on it according to the teachings of the subject invention, and a comparison is made with the database.

  20. Quantum physics meets biology

    E-Print Network [OSTI]

    Markus Arndt; Thomas Juffmann; Vlatko Vedral

    2009-11-01

    Quantum physics and biology have long been regarded as unrelated disciplines, describing nature at the inanimate microlevel on the one hand and living species on the other hand. Over the last decades the life sciences have succeeded in providing ever more and refined explanations of macroscopic phenomena that were based on an improved understanding of molecular structures and mechanisms. Simultaneously, quantum physics, originally rooted in a world view of quantum coherences, entanglement and other non-classical effects, has been heading towards systems of increasing complexity. The present perspective article shall serve as a pedestrian guide to the growing interconnections between the two fields. We recapitulate the generic and sometimes unintuitive characteristics of quantum physics and point to a number of applications in the life sciences. We discuss our criteria for a future quantum biology, its current status, recent experimental progress and also the restrictions that nature imposes on bold extrapolations of quantum theory to macroscopic phenomena.

  1. Proportional Relationships in Biology

    E-Print Network [OSTI]

    Lega, Joceline

    Proportional Relationships in Biology #12;Bell Ringer... 1) Are 2/3 and 6/12 proportional? 1) No; 6/12 = 1/2 ! 2/3 2) Are 2/3 and 10/15 proportional? 1) Yes; 2/3 = (2*5)/(3*5) = 10/15 3) Are 2/3 and 4/9 proportional? 1) No; both are simplified #12;Proportional Shapes · What does it mean for two shapes

  2. Computational biology and high performance computing

    E-Print Network [OSTI]

    Shoichet, Brian

    2011-01-01

    Paper in Computational Biology The First Step Beyond theM . Glaeser, Mol. & Cell Biology, UCB and Life SciencesLBNL-44460 Computational Biology and High Performance

  3. Nutritional systems biology of type 2 diabetes

    E-Print Network [OSTI]

    Zhao, Y; Barrere-Cain, RE; Yang, X

    2015-01-01

    HF (2015) Circadian systems biology in Metazoa. BriefingsNutritional systems biology: defini- tions and approaches.PAPER Nutritional systems biology of type 2 diabetes Yuqi

  4. DEPARTMENT OF DEPARTMENT OF BIOLOGY

    E-Print Network [OSTI]

    Turc, Catalin

    Masters of Science Degree Plan A: Thesis DEPARTMENT OF BIOLOGY CASE WESTERN RESERVE UNIVERSITY #12;DEPARTMENT OF BIOLOGY Masters of Science Degree (Plan A) Thesis The Plan A Master of Science Degree in Biology is a thesis,graduate degree program.The purpose of the program is to provide advanced exposure

  5. Translational Biology, Medicine, and Health

    E-Print Network [OSTI]

    Crawford, T. Daniel

    Translational Biology, Medicine, and Health PhDProgram Admissions The program seeks highly. PhD Program in Translational Biology, Medicine, and Health Focus Areas Cancer Development, Aging 24016 avanwart@vt.edu · www.tbmh.vt.edu www . tbmh.vt.edu #12;Translational Biology, Medicine

  6. Metabolic Engineering and Synthetic Biology in Strain Development Every year, we consume about 27 billion barrels of fossil oil.

    E-Print Network [OSTI]

    billion barrels of fossil oil. This enormous amount of oil is used for fueling our cars and airplanes

  7. Microfluidics for Synthetic Biology : : developing technologies for study of gene networks in single cells and large populations

    E-Print Network [OSTI]

    Razinkov, Ivan Alexandrovich

    Stage Ti-CT-E Motorized Condenser Turret MEL51910 Ti-C-LWDLWD Lens Unit for SystemTurret 1 MEL56200 System LWD Ph L Annuli MEH31040 TE-C LWD

  8. Synthetic biology in yeast : reconstructing the galactose network to probe the role of feedback induction in response to metabolic stimuli

    E-Print Network [OSTI]

    Ferry, Michael Stephen

    2010-01-01

    Motorized Stage Ti-CT-E Motorized Condenser Turret Ti-C-LWDLWD Lens Unit for SystemCondenser Turret 1 System LWD Ph L Annuli TE-C LWD Ph1

  9. Microfluidics for Synthetic Biology : : developing technologies for study of gene networks in single cells and large populations

    E-Print Network [OSTI]

    Razinkov, Ivan Alexandrovich

    is usually performed in a cleanroom environment. A number offrom a Class 100 cleanroom to a basic HEPA filtered roomThe latter type of non-cleanroom man- ufacturing environment

  10. Synthetic biology in yeast : reconstructing the galactose network to probe the role of feedback induction in response to metabolic stimuli

    E-Print Network [OSTI]

    Ferry, Michael Stephen

    2010-01-01

    is usually performed in a cleanroom environment. A number offrom a Class 100 cleanroom to a basic HEPA filtered roomThe latter type of non-cleanroom man- ufacturing environment

  11. Microfluidics for Synthetic Biology : : developing technologies for study of gene networks in single cells and large populations

    E-Print Network [OSTI]

    Razinkov, Ivan Alexandrovich

    5.5.1 MicrofluidicsMicroscopy and Microfluidics . . . . . . . . . . . . 3.7.53.6.2 Microfluidics and Microscopy . . . . . . . . . . . .

  12. Synthetic Biology and Bioenergy: Helping the Good Guy and Stopping the Bad (2014 DOE JGI Genomics of Energy & Environment Meeting)

    SciTech Connect (OSTI)

    Mercedes-Roca, Maria [Zamorano Panamerican Agriculture School

    2014-03-19

    Maria Mercedes-Roca of the Zamorano Panamerican Agriculture School speaks at the 9th Annual Genomics of Energy & Environment Meeting on March 20, 2014 in Walnut Creek, Calif.

  13. Aromatizing Olefin Metathesis by Ligand Isolation inside a Metal-Organic Framework

    E-Print Network [OSTI]

    alternative synthetic protocols have emerged: they are (i) postsynthesis modification9 (PSM) and (ii) solvent-assisted linker exchange10 (SALE). PSM refers to chemical modifications of the organic struts in MOFs to either. It is worthy of note that few reports13 describe C-C bond-forming reactions by PSM. By contrast, SALE allows

  14. Vapor-Phase Metalation by Atomic Layer Deposition in a Metal-Organic Framework

    E-Print Network [OSTI]

    Vapor-Phase Metalation by Atomic Layer Deposition in a Metal- Organic Framework Joseph E. Mondloch introduce a new synthetic strategy capable of metallating MOFs from the gas phase: atomic layer deposition and in some instances host- guest interactions may lead to unstable metal@MOFs. Atomic layer deposition (ALD

  15. THREE-DIMENSIONAL LONGWAVE INFRARED (LWIR) SYNTHETIC IMAGE GENERATION INCORPORATING ANGULAR EMJSSWITY EFFECTS USING RAY-

    E-Print Network [OSTI]

    Salvaggio, Carl

    . These routines require a sequence of images to evaluate tracking algorithms. The evaluation of sensor performanceTHREE-DIMENSIONAL LONGWAVE INFRARED (LWIR) SYNTHETIC IMAGE GENERATION INCORPORATING ANGULAR Memorial Drive Rochester, New York 14623-0887 ABSTRAO A technique for longwave infrared (LWIR) synthetic

  16. Monitoring of SAGD Process: Seismic Interpretation of Ray+Born Synthetic 4D Data

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Monitoring of SAGD Process: Seismic Interpretation of Ray+Born Synthetic 4D Data C. Joseph1, G ­ Monitoring of SAGD Process: Seismic Interpretation of Ray+Born Synthetic 4D Data ­ The objective of this study is to evaluate which production information can be deduced from a 4D seismic survey during

  17. Computational Study of the Effect of Slot Orientation on Synthetic Jet-Based

    E-Print Network [OSTI]

    Mittal, Rajat

    -space average of jet exit velocity during the expulsion phase, m/sec vJ = jet exit velocity, m/sec v = cross-stream1 Computational Study of the Effect of Slot Orientation on Synthetic Jet-Based Separation Control, MD-21218 Abstract A computational study is conducted to explore the effect of synthetic jet

  18. Simultaneous Inversion of Production Data and Seismic Attributes: Application to a Synthetic

    E-Print Network [OSTI]

    Boyer, Edmond

    Simultaneous Inversion of Production Data and Seismic Attributes: Application to a Synthetic SAGD and Seismic Attributes: Application to a Synthetic SAGD Produced Field Case -- The joint use of production such as facies, porosity and permeability into reservoirs from production data and seismic attributes

  19. Numerical Study of Large Aspect-Ratio Synthetic Jets B. R. Ravi*

    E-Print Network [OSTI]

    Mittal, Rajat

    Numerical Study of Large Aspect-Ratio Synthetic Jets B. R. Ravi* and R. Mittal Department jets. A rectangular synthetic jet of aspect-ratio (AR) 8.0 issuing into quiescent air at jet Reynolds number of 300 and Stokes numbers of 6.84 and a jet of infinite aspect ratio with jet Reynolds number 200

  20. Facilitated Phospholipid Flip-Flop Using Synthetic Steroid-Derived Translocases

    E-Print Network [OSTI]

    Smith, Bradley D.

    Facilitated Phospholipid Flip-Flop Using Synthetic Steroid-Derived Translocases Timothy N. Lambert research.4 Previously, we have reported that tris(2-aminoethyl)amine (tren)-derived translocases can of significantly more active synthetic translocases derived from cholic acid.6 Cholate derivatives 1-5 were

  1. Biological Materials that REQUIRE an Export License ALL biological agents and biologically derived substances specifically developed, configured,

    E-Print Network [OSTI]

    Jornsten, Rebecka

    Biological Materials that REQUIRE an Export License · ALL biological agents and biologically nationals or to be exported. List of Biological Materials that MAY Require an Export License (including

  2. Biology/Marine Biology Prizes/Awards/Scholarships 2004/05 University Medal in Biology Anna London

    E-Print Network [OSTI]

    Gunawardena, Arunika

    Biology/Marine Biology Prizes/Awards/Scholarships 2004/05 University Medal in Biology Anna London University Medal in Marine Biology Jennifer Frail Hugh P. Bell Scholarships Ivy Whitehorn, Jennifer Frail

  3. Biology/Marine Biology Prizes/Awards/Scholarships 2003/04 University Medal in Biology Andrew Gillis

    E-Print Network [OSTI]

    Gunawardena, Arunika

    Biology/Marine Biology Prizes/Awards/Scholarships 2003/04 University Medal in Biology Andrew Gillis University Medal in Marine Biology Kent Russell Hugh P. Bell Scholarships Andrew Gillis, Stephanie Wood

  4. Biology/Marine Biology Prizes/Awards/Scholarships 2006/07 University Medal in Biology Yassein Shamout

    E-Print Network [OSTI]

    Gunawardena, Arunika

    Biology/Marine Biology Prizes/Awards/Scholarships 2006/07 University Medal in Biology Yassein Shamout University Medal in Marine Biology Sophie Whoriskey Hugh P. Bell Scholarships Shana Watanabe

  5. Biology/Marine Biology Prizes/Awards/Scholarships 2007/08 University Medal in Biology Faiza Siddiqi, Ashley Smith

    E-Print Network [OSTI]

    Gunawardena, Arunika

    Biology/Marine Biology Prizes/Awards/Scholarships 2007/08 University Medal in Biology Faiza Siddiqi, Ashley Smith University Medal in Marine Biology Shana Watanabe Hugh P. Bell Scholarships Faiza Siddiqi

  6. Biology/Marine Biology Prizes/Awards/Scholarships 2005/06 University Medal in Biology Oliver Barker

    E-Print Network [OSTI]

    Gunawardena, Arunika

    Biology/Marine Biology Prizes/Awards/Scholarships 2005/06 University Medal in Biology Oliver Barker University Medal in Marine Biology Katy Garant Hugh P. Bell Scholarships Oliver Barker, Alison Green, Carmen

  7. Biology/Marine Biology Prizes/Awards/Scholarships 2002/03 University Medal in Biology Kate Turner

    E-Print Network [OSTI]

    Gunawardena, Arunika

    Biology/Marine Biology Prizes/Awards/Scholarships 2002/03 University Medal in Biology Kate Turner University Medal in Marine Biology Shane Gero University Medal in French Annette Woods University Medal

  8. Energy from biological processes

    SciTech Connect (OSTI)

    Not Available

    1980-07-01

    This assessment responds to a request by the Senate Committee on Commerce, Science, and Transportation for an evaluation of the energy potential of various sources of plant and animal matter (biomass). This report complements an earlier OTA report on the Application of Solar Technology to Today's Energy Needs in evaluating the major solar energy resources available to the United States. The findings also will serve as part of the material to be used in an upcoming OTA assessment of synthetic fuels for transportation. This volume presents analyses of prominent biomass issues, summaries of four biomass fuel cycles, a description of biomass' place in two plausible energy futures, and discussions of policy options for promoting energy from biomass. The four fuel cycles - wood, alcohol fuels, grasses and crop residues, and animal wastes - were chosen because of their near- to mid-term energy potential and because of the public interest in them. A second volume presents technical analyses of the resource base, conversion technologies, and end uses that provide a basis for the discussion in this volume. Also included in Volume II are various unconventional approaches to bioenergy production as well as the use of biomass to produce chemicals.

  9. Fate of Mercury in Synthetic Gypsum Used for Wallboard Production

    SciTech Connect (OSTI)

    Jessica Marshall Sanderson

    2006-06-01

    This report presents and discusses results from Task 5 of the study ''Fate of Mercury in Synthetic Gypsum Used for Wallboard Production,'' performed at a full-scale commercial wallboard plant. Synthetic gypsum produced by wet flue gas desulfurization (FGD) systems on coal-fired power plants is commonly used in the manufacture of wallboard. The FGD process is used to control the sulfur dioxide emissions which would result in acid rain if not controlled. This practice has long benefited the environment by recycling the FGD gypsum byproduct, which is becoming available in increasing quantities, decreasing the need to landfill this material, and increasing the sustainable design of the wallboard product. However, new concerns have arisen as recent mercury control strategies developed for power plants involve the capture of mercury in FGD systems. The objective of this study is to determine whether any mercury is released into the atmosphere when the synthetic gypsum material is used as a feedstock for wallboard production. The project is being co-funded by the U.S. DOE National Energy Technology Laboratory (Cooperative Agreement DE-FC26-04NT42080), USG Corporation, and EPRI. USG Corporation is the prime contractor, and URS Group is a subcontractor. The project scope includes five discrete tasks, each conducted at various USG wallboard plants using synthetic gypsum from different FGD systems. The five tasks were to include (1) a baseline test, then variations representing differing power plant (2) emissions control configurations, (3) treatment of fine gypsum particles, (4) coal types, and (5) FGD reagent types. However, Task 5, which was to evaluate gypsum produced from an alternate FGD reagent, could not be conducted as planned. Instead, Task 5 was conducted at conditions similar to a previous task, Task 3, although with gypsum from an alternate FGD system. In this project, process stacks in the wallboard plant have been sampled using the Ontario Hydro method. The stack locations sampled for each task include a dryer for the wet gypsum as it enters the plant and a gypsum calciner. The stack of the dryer for the wet wallboard product was also tested as part of this task, and was tested as part of Tasks 1 and 4. Also at each site, in-stream process samples were collected and analyzed for mercury concentration before and after each significant step in wallboard production. The Ontario Hydro results, process sample mercury concentration data, and process data were used to construct mercury mass balances across the wallboard plants. Task 5 was conducted at a wallboard plant processing synthetic gypsum from a power plant that fires Eastern bituminous coal. The power plant is equipped with a selective catalytic reduction (SCR) system for NOX emissions control, but the SCR was bypassed during the time period the gypsum tested was produced. The power plant has a single-loop, open spray tower, limestone reagent FGD system, with forced oxidation conducted in a reaction tank integral with the FGD absorber. The FGD system has gypsum fines blow down as part of the dewatering step. Gypsum fines blow down is believed to be an important variable that impacts the amount of mercury in the gypsum byproduct and possibly its stability during the wallboard process. The results of the Task 5 stack testing, as measured by the Ontario Hydro method, detected that an average of 51% of the incoming mercury in the FGD gypsum was emitted during wallboard production. These losses were distributed as 2% or less each across the wet gypsum dryer and product wallboard dryer, and about 50% across the gypsum calciner. Emissions were similar to what Task 3 results showed, on both a percentage and a mass basis, for gypsum produced by a power plant firing bituminous coal and also having gypsum fines blow down as part of the FGD dewatering scheme. As was seen in the Task 1 through 4 results, most of the mercury detected in the stack testing on the wet gypsum dryer and kettle calciner was in the form of elemental mercury. In the wallboard dryer kiln, a more signific

  10. Management Principles for Nonproliferation Organizations

    SciTech Connect (OSTI)

    Frazar, Sarah L.; Hund, Gretchen

    2012-03-06

    This paper identifies business models and six management principles that can be applied by a nonproliferation organization to maximize the value and effectiveness of its products. The organizations responsible for reducing the nuclear proliferation threat have experienced a substantial growth in responsibility and visibility since the September 11 attacks. Since then, the international community has witnessed revelations of clandestine nuclear facilities, nuclear black markets, periodic nuclear tests, and a resurgence of interest by countries worldwide in developing nuclear capabilities. The security environment will likely continue to evolve in unexpected ways since most of the proliferation threats with which the world will be forced to contend remain unforeseen. To better prepare for and respond to this evolving security environment, many nonproliferation organizations are interested in finding new or better ways to increase the effectiveness and efficiency of their operations. Of course, all organizations, whether they are market driven or non-profit, must operate effectively and efficiently if they are to succeed. Indeed, as this study demonstrates, many of the management principles that this study recommends can help all organizations succeed. However, this study pays particular attention to nonproliferation organizations because of the mission they are responsible for fulfilling. Nonproliferation organizations, including nonproliferation programs that operate within a larger national security organization, are responsible for reducing the threat of nuclear, chemical and biological weapons. These organizations have an enduring mandate from the public and the international community not to fail in the completion of their mission for failure could have detrimental impacts on international security, public health and the environment. Moreover, the public expects nonproliferation organizations and programs to fulfill their mission, even when resources are limited. They are expected to anticipate and react quickly to prevent a potential threat while staying accountable to their public stakeholders, many of whom remain unaware of the very threats the organization is trying to address. When budgets are flush, it is easy to believe that money will solve all problems; but during times of economic hardship, managers must rely on creative and cost-effective management approaches to implement their missions. Fortunately, managers of nonproliferation organizations can draw on a wealth of research on organizational design and culture to help them identify the management strategies most appropriate for them. Such research can help nonproliferation managers think about their own organizational structures and cultures and adapt accepted management principles to their unique organizational mission. This analytical process is not straight forward, as some managers may find themselves taking risks that others might not take, such as making ostensibly risky investments for the common good, or supporting creative thinking to help mission accomplishment. Some management principles that are relatively straightforward for other organizations may be difficult to envision and implement in a nonproliferation organization. Therefore, the goal of this study is to help nonproliferation managers identify management principles that can be implemented in a nonproliferation organization and, in the process, help maximize the value of the organization's products and effectiveness of its mission.

  11. Biology/Marine Biology Prizes/Awards/Scholarships 2010/11 University Medal in Biology Jennifer Kalil

    E-Print Network [OSTI]

    Gunawardena, Arunika

    Biology/Marine Biology Prizes/Awards/Scholarships 2010/11 University Medal in Biology Jennifer Kalil University Medal in Marine Biology John O'Brien University Silver Medal John O'Brien Hugh P. Bell Developmental Biology Prize Alexandra Preston Vemco Scholarship in Marine Biology Jessica Carriere

  12. Biology/Marine Biology Prizes/Awards/Scholarships 2011/12 University Medal in Biology Jaime Wertman

    E-Print Network [OSTI]

    Gunawardena, Arunika

    Biology/Marine Biology Prizes/Awards/Scholarships 2011/12 University Medal in Biology Jaime Wertman University Medal in Marine Biology Cylia Civelek Hugh P. Bell Scholarships Sarah McBoyle, Lauren Kay, Daniel Developmental Biology Prize Siwar Arda Vemco Scholarship in Marine Biology Stacey Henderson Cecelia Rajaratnam

  13. Montana State University 1 Cell Biology and

    E-Print Network [OSTI]

    Maxwell, Bruce D.

    Montana State University 1 Cell Biology and Neuroscience The department participates: MSU's programs in the biological sciences are distributed across multiple departments. MSU does not have a single Department of Biology. For additional options see Biological Sciences (http

  14. 7.013 Introductory Biology, Spring 2005

    E-Print Network [OSTI]

    Sive, Hazel L.

    The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological ...

  15. Autofermentative Biological Hydrogen Production by Cyanobacteria...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Autofermentative Biological Hydrogen Production by Cyanobacteria Autofermentative Biological Hydrogen Production by Cyanobacteria Presentation by Charles Dismukes, Rutgers...

  16. Biological and Environmental Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room News PublicationsAudits & InspectionsBeryllium andSamplerBiological Imaging by

  17. Inorganic metal oxide/organic polymer nanocomposites and method thereof

    DOE Patents [OSTI]

    Gash, Alexander E.; Satcher, Joe H.; Simpson, Randy

    2004-03-30

    A synthetic method for preparation of hybrid inorganic/organic energetic nanocomposites is disclosed herein. The method employs the use of stable metal inorganic salts and organic solvents as well as an organic polymer with good solubility in the solvent system to produce novel nanocomposite energetic materials. In addition, fuel metal powders (particularly those that are oxophillic) can be incorporated into composition. This material has been characterized by thermal methods, energy-filtered transmission electron microscopy (EFTEM), N.sub.2 adsoprtion/desorption methods, and Fourier-Transform (FT-IR) spectroscopy. According to these characterization methods the organic polymer phase fills the nanopores of the composite material, providing superb mixing of the component phases in the energetic nanocomposite.

  18. ENVIRONMENTAL REVIEW FOR CATEGORICAL EXCLUSION DETERMINATION

    Office of Environmental Management (EM)

    engineered organisms, synthetic biology, X governmentally designated noxious weeds, or invasive species, unless the proposed activity would be contained or confined in a manner...

  19. ENVIRONMENTAL REVIEW FOR CATEGORICAL EXCLUSION DETERMINATION

    Office of Environmental Management (EM)

    engineered organisms, synthetic X biology, governmentally designated noxious weeds, or invasive species, unless the proposed activity would be contained or confined in a manner...

  20. ENVIRONMENTAL REVIEW FOR CATEGORICAL EXCLUSION DETERMINATION

    Office of Environmental Management (EM)

    engineered organisms, synthetic biology, X govemmentally designated noxious weeds, or invasive species, unless the proposed activity would be contained or confined in a manner...

  1. Department of Biology and Marine Biology Merit Scholarship Fund: The Department of Biology and Marine Biology Merit Scholarship is hereby created as a

    E-Print Network [OSTI]

    Olszewski Jr., Edward A.

    Department of Biology and Marine Biology Merit Scholarship Fund: The Department of Biology and Marine Biology Merit Scholarship is hereby created as a named fund at the University of North Carolina at Wilmington. The scholarship is being created by the Department of Biology and Marine Biology and will be used

  2. Ordered organic-organic multilayer growth

    DOE Patents [OSTI]

    Forrest, Stephen R; Lunt, Richard R

    2015-01-13

    An ordered multilayer crystalline organic thin film structure is formed by depositing at least two layers of thin film crystalline organic materials successively wherein the at least two thin film layers are selected to have their surface energies within .+-.50% of each other, and preferably within .+-.15% of each other, whereby every thin film layer within the multilayer crystalline organic thin film structure exhibit a quasi-epitaxial relationship with the adjacent crystalline organic thin film.

  3. Lynx: A High-Resolution Synthetic Aperture Radar

    SciTech Connect (OSTI)

    Doerry, A.W.; Hensley, W.H.; Pace, F.; Stence, J.; Tsunoda, S.I.; Walker, B.C.; Woodring, M.

    1999-03-08

    Lynx is a high resolution, synthetic aperture radar (SAR) that has been designed and built by Sandia National Laboratories in collaboration with General Atomics (GA). Although Lynx may be operated on a wide variety of manned and unmanned platforms, it is primarily intended to be fielded on unmanned aerial vehicles. In particular, it may be operated on the Predator, I-GNAT, or Prowler II platforms manufactured by GA Aeronautical Systems, Inc. The Lynx production weight is less than 120 lb. and has a slant range of 30 km (in 4 mm/hr rain). It has operator selectable resolution and is capable of 0.1 m resolution in spotlight mode and 0.3 m resolution in stripmap mode. In ground moving target indicator mode, the minimum detectable velocity is 6 knots with a minimum target cross-section of 10 dBsm. In coherent change detection mode, Lynx makes registered, complex image comparisons either of 0.1 m resolution (minimum) spotlight images or of 0.3 m resolution (minimum) strip images. The Lynx user interface features a view manager that allows it to pan and zoom like a video camera. Lynx was developed under corporate finding from GA and will be manufactured by GA for both military and commercial applications. The Lynx system architecture will be presented and some of its unique features will be described. Imagery at the finest resolutions in both spotlight and strip modes have been obtained and will also be presented.

  4. Experimental Study on Shear Fatigue Behavior and Stiffness Performance of Warm Mix Asphalt by adding Synthetic Wax

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    by adding Synthetic Wax C. Petita , A. Milliena , F. Canestrarib , V. Pannunziob , A. Virgilib a Université.petit@unilim.fr , Phone : +33555934519 Abstract Synthetic waxes produced by standard and registered processes may be used. The present article serves to compare the mechanical performance of a WMA produced by adding synthetic wax

  5. The Climate for Faculty of Color in the Biological & Physical Sciences at UW-

    E-Print Network [OSTI]

    Sheridan, Jennifer

    #12;The Climate for Faculty of Color in the Biological & Physical Sciences at UW- Madison Jennifer Sheridan WISELI University of Wisconsin-Madison #12;Climate The atmosphere or ambience of an organization as perceived by its members. An organization's climate is reflected in its structures, policies, and practices

  6. Water Research 39 (2005) 38193826 Increased biological hydrogen production with reduced

    E-Print Network [OSTI]

    2005-01-01

    Water Research 39 (2005) 3819­3826 Increased biological hydrogen production with reduced organic to understand the effect of organic loading on H2 production in chemostat reactors. In order to vary the glucose is produced with acetate as a product (4 mol-H2/mol-acetate) than with butyrate (2 mol-H2/mol

  7. Understanding calcification in bone regeneration through a synthetic biomineralization-based approach

    E-Print Network [OSTI]

    Phadke, Ameya

    2012-01-01

    Synthesis of organic/inorganic composite materials throughsynthesis of organic/inorganic composite materials.

  8. Z .Synthetic Metals 114 2000 201207 www.elsevier.comrlocatersynmet

    E-Print Network [OSTI]

    Huang, Yanyi

    -sensitized solar cell, it is necessary to probe the sensitization of other kinds of dyes, such as organic molecules solar cell 8 . Nanocrystalline semiconductor films are highly porous, thus having a large internal work on dye-sensitized solar cell is centered on w xruthennium­bipyridine complexes 9­11 sensitizing

  9. Healthcare & Biology Licenses Available | ORNL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ID 200802058, 200802114) 200802139 Universal Gene Transfer Technology for Gram Positive Bacteria 200802151 Determining Optical Properties of Biological Tissues 200802153 Combined...

  10. CollegeofScience Biological Sciences

    E-Print Network [OSTI]

    Hickman, Mark

    ,populations,and even ecosystems. Our courses will help prepare you for a career in biology,be it in biodiversity

  11. Michael Levitt and Computational Biology

    Office of Scientific and Technical Information (OSTI)

    Levitt, PhD, professor of structural biology at the Stanford University School of Medicine, has won the 2013 Nobel Prize in Chemistry. ... Levitt ... shares the ... prize with...

  12. Experimental Demonstration of a Synthetic Lorentz Force by Using Radiation Pressure

    E-Print Network [OSTI]

    Šanti?, N; Aumiler, D; Buljan, H; Ban, T

    2015-01-01

    Synthetic magnetism in cold atomic gases opened the doors to many exciting novel physical systems and phenomena. Ubiquitous are the methods used for the creation of synthetic magnetic fields. They include rapidly rotating Bose-Einstein condensates employing the analogy between the Coriolis and the Lorentz force, and laser-atom interactions employing the analogy between the Berry phase and the Aharonov-Bohm phase. Interestingly, radiation pressure - being one of the most common forces induced by light - has not yet been used for synthetic magnetism. We experimentally demonstrate a synthetic Lorentz force, based on the radiation pressure and the Doppler effect, by observing the centre-of-mass motion of a cold atomic cloud. The force is perpendicular to the velocity of the cold atomic cloud, and zero for the cloud at rest. Our novel concept is straightforward to implement in a large volume, for a broad range of velocities, and can be extended to different geometries.

  13. Syntrophic exchange in synthetic microbial communities Michael T. Meea,b

    E-Print Network [OSTI]

    Collins, James J.

    modeling Microbes are abundantly found in almost every part of the world, living in communities synthetic microbiomes for various biotechnological applications (1­3). Numerous such examples have been

  14. Revisiting the security of speaker verification systems against imposture using synthetic speech 

    E-Print Network [OSTI]

    De Leon, P. L.; Apsingekar, V. R.; Pucher, M.; Yamagishi, Junichi

    2010-01-01

    In this paper, we investigate imposture using synthetic speech. Although this problem was first examined over a decade ago, dramatic improvements in both speaker verification (SV) and speech synthesis have renewed ...

  15. Global Synthetic & Bio-Based Lubricants Market | OpenEI Community

    Open Energy Info (EERE)

    picture Submitted by John55364(100) Contributor 14 May, 2015 - 05:53 Expansion of Automotive Industries to Boost the Global Synthetic and Bio-Based Lubricants Market Global...

  16. Identification of conserved chromatin-regulatory complexes among the class B synthetic multivulva proteins

    E-Print Network [OSTI]

    Harrison, Melissa M

    2006-01-01

    The class A, B, and C synthetic Multivulva (synMuv) genes act redundantly to antagonize Ras-mediated vulval induction in C. elegans. Many of these genes encode proteins that are likely to function in transcriptional ...

  17. A portable RNA sequence whose recognition by a synthetic antibody facilitates structural determination

    E-Print Network [OSTI]

    Koldobskaya, Yelena

    RNA crystallization and phasing represent major bottlenecks in RNA structure determination. Seeking to exploit antibody fragments as RNA crystallization chaperones, we have used an arginine-enriched synthetic Fab library ...

  18. High-field remanence properties of synthetic and natural submicrometre haematites and goethites: significance

    E-Print Network [OSTI]

    High-field remanence properties of synthetic and natural submicrometre haematites and goethites September 2004 Editor: V. Courtillot Abstract Haematite and goethite are significant magnetic components both of marine and terrestrial sediments. Variable magnetic behaviour in haematite and goethite has

  19. Structural Analysis of Human and Bovine Bone for Development of Synthetic Materials 

    E-Print Network [OSTI]

    Jang, Eunhwa

    2012-10-19

    With increasing demands in bone repair and replacement, this research investigates the microstructure, properties and performance of bovine bone, human bone, and synthetic materials. Doing so, experimental approaches were used to exam and compare...

  20. Synthetic mimics of mammalian cell surface receptors: prosthetic molecules that augment living cells

    E-Print Network [OSTI]

    Peterson, Blake R.

    2005-09-08

    -alkyl derivatives of 3?-cholesterylamine linked to motifs that bind cell-impermeable ligands. When added to living mammalian cells, these synthetic receptors insert into cellular plasma membranes, project ligand-binding small molecules or peptides from the cell...

  1. Volumetric analysis of fish swimming hydrodynamics using synthetic aperture particle image velocimetry

    E-Print Network [OSTI]

    Mendelson, Leah Rose

    2013-01-01

    Abstract This thesis details the implementation of a three-dimensional PIV system to study the hydrodynamics of freely swimming Giant Danio (Danio aequipinnatus). Volumetric particle fields are reconstructed using synthetic ...

  2. New target detector based on geometrical perturbation filters for polarimetric Synthetic Aperture Radar (POL-SAR) 

    E-Print Network [OSTI]

    Marino, Armando

    2010-01-01

    Synthetic Aperture Radar (SAR) is an active microwave remote sensing system able to acquire high resolution images of the scattering behaviour of an observed scene. The contribution of SAR polarimetry (POLSAR) in detection ...

  3. Modeling of D/C motor driven synthetic jet acutators for flow separation control 

    E-Print Network [OSTI]

    Balasubramanian, Ashwin Kumar

    2004-11-15

    The objective of this research is to present a theoretical study of the compressibility effects on the performance of an electric D/C motor driven synthetic jet actuator for flow separation control. Hot wire anemometer experiments were conducted...

  4. Ribozyme-based insulator parts buffer synthetic circuits from genetic context

    E-Print Network [OSTI]

    Lou, Chunbo

    Synthetic genetic programs are built from circuits that integrate sensors and implement temporal control of gene expression. Transcriptional circuits are layered by using promoters to carry the signal between circuits. In ...

  5. Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses

    E-Print Network [OSTI]

    Moon, James J.

    Vaccines based on recombinant proteins avoid the toxicity and antivector immunity associated with live vaccine (for example, viral) vectors, but their immunogenicity is poor, particularly for CD8+ T-cell responses. Synthetic ...

  6. Focused synthetic aperture radar processing of ice-sounder data collected over the Greenland ice sheet

    E-Print Network [OSTI]

    Legarsky, J.; Gogineni, Sivaprasad; Akins, T. L.

    2001-10-01

    We developed a synthetic aperture radar (SAR) processing algorithm for airborne/spaceborne ice-sounding radar systems and applied it to data collected in Greenland. By using focused SAR (phase-corrected coherent averaging), we improved along...

  7. ATTENTION BIOLOGY/MARINE BIOLOGY If you think that you qualify, bring this to the attention of a biology faculty

    E-Print Network [OSTI]

    Gunawardena, Arunika

    ATTENTION BIOLOGY/MARINE BIOLOGY STUDENTS: If you think that you qualify, bring this to the attention of a biology faculty member and seek their nomination. The Gary Hicks Memorial Award The Gary in the Biology Department at Dalhousie University for 27 years where he taught developmental and plant biology

  8. Biology/Marine Biology Prizes/Awards/Scholarships 2008/09 University Medal in Biology Alyssa Byers-Heinlein

    E-Print Network [OSTI]

    Gunawardena, Arunika

    Biology/Marine Biology Prizes/Awards/Scholarships 2008/09 University Medal in Biology Alyssa Byers-Heinlein University Medal in Marine Biology Matthew Morris Avery Prize Jessica Arbour Hugh P. Bell Scholarships, Elisabeth Oakham Vemco Scholarship in Marine Biology Matthew Morris #12;

  9. Biology/Marine Biology Prizes/Awards/Scholarships 2009/10 University Medal in Biology Jinnie Kim

    E-Print Network [OSTI]

    Gunawardena, Arunika

    Biology/Marine Biology Prizes/Awards/Scholarships 2009/10 University Medal in Biology Jinnie Kim University Medal in Marine Biology Jesse Kelly University Silver Medal Jinnie Kim Hugh P. Bell Scholarships Vemco Scholarship in Marine Biology Jessie Short #12;

  10. Procedure for matching synfuel users with potential suppliers. Appendix B. Proposed and ongoing synthetic fuel production projects

    SciTech Connect (OSTI)

    1981-08-07

    To assist the Department of Energy, Office of Fuels Conversion (OFC), in implementing the synthetic fuel exemption under the Powerplant and Industrial Fuel Use Act (FUA) of 1978, Resource Consulting Group, Inc. (RCG), has developed a procedure for matching prospective users and producers of synthetic fuel. The matching procedure, which involves a hierarchical screening process, is designed to assist OFC in: locating a supplier for a firm that wishes to obtain a synthetic fuel exemption; determining whether the fuel supplier proposed by a petitioner is technically and economically capable of meeting the petitioner's needs; and assisting the Synthetic Fuels Corporation or a synthetic fuel supplier in evaluating potential markets for synthetic fuel production. A data base is provided in this appendix on proposed and ongoing synthetic fuel production projects to be used in applying the screening procedure. The data base encompasses a total of 212 projects in the seven production technologies.

  11. Process for gasification using a synthetic CO.sub.2 acceptor

    DOE Patents [OSTI]

    Lancet, Michael S. (Pittsburgh, PA); Curran, George P. (Pittsburgh, PA)

    1980-01-01

    A gasification process is disclosed using a synthetic CO.sub.2 acceptor consisting essentially of at least one compound selected from the group consisting of calcium oxide and calcium carbonate supported in a refractory carrier matrix, the carrier having the general formula Ca.sub.5 (SiO.sub.4).sub.2 CO.sub.3. A method for producing the synthetic CO.sub.2 acceptor is also disclosed.

  12. Lighting system with thermal management system having point contact synthetic jets

    DOE Patents [OSTI]

    Arik, Mehmet; Weaver, Stanton Earl; Kuenzler, Glenn Howard; Wolfe, Jr., Charles Franklin; Sharma, Rajdeep

    2013-12-10

    Lighting system having unique configurations are provided. For instance, the lighting system may include a light source, a thermal management system and driver electronics, each contained within a housing structure. The light source is configured to provide illumination visible through an opening in the housing structure. The thermal management system includes a plurality of synthetic jets. The synthetic jets are arranged within the lighting system such that they are secured at contact points.

  13. Muffle furnace evaluation of FGD sludge-coal-clay mixtures as potential synthetic aggregates 

    E-Print Network [OSTI]

    Pettit, Jesse William

    1978-01-01

    MUFFLE FURNACE EVALUATION OF FGD SLUDGE-COAL-CLAY MIXTURES AS POTENTIAL SYNTHETIC AGGREGATES A Thesis JESSE WILLIAM PETTIT Submitted to the Graduate College of Texas ASM University in Partial fulfillment of the requirement for the degree... of MASTER OF SCIENCE December 1978 Major Suoject: Civil Engineering MUFFLE FURNACE EVALUATION OF FGD SLUDGE-COAL-CLAY MIXTURES AS POTENTIAL SYNTHETIC AGGREGATES A Theseus by JESSE WILLIAM PETTIT Approved as to style and content by: r n of Commi tee...

  14. Biological Engineering integrates life sciences

    E-Print Network [OSTI]

    Chen, Tsuhan

    of biological systems. Biological Engineering impacts the well-being of humans, plants, and animals through and global challenges such as ensuring safe and sustainable food and energy supplies, protecting natural agencies. Products of their efforts help ensure a safe and adequate supply of food and water, create new

  15. Cheatgrass Biology, Ecology, and Management

    E-Print Network [OSTI]

    Maxwell, Bruce D.

    Cheatgrass Biology, Ecology, and Management Fabián Menalled menalled@montana.edu 406-994-4783 Montana State #12;http://ipm.montana.edu/cropweeds #12;#12;· Biology and identification of brome species secalinus Not found in MT #12;Cheatgrass Japanese brome #12;Pictures from Interactive Encyclopedia of North

  16. Organic Photovoltaics Philip Schulz

    E-Print Network [OSTI]

    Firestone, Jeremy

    Field Effect Transistors Organic Light Emitting Diodes Organic Solar Cells .OFET, OTFT .RF-ID tag 1977 ­ Conductivity in polymers 1986 ­ First heterojunction OPV 1987 ­ First organic light emitting diode (OLED) 1993 ­ First OPV from solution processing 2001 ­ First certified organic solar cell with 2

  17. Departmental Organization and Management

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1993-06-10

    Effective immediately, the Departmental organization structure reflected in the chart at Attachment 1 has been approved.

  18. Interactions of Jet Fuels with Nitrile O-Rings: Petroleum-Derived versus Synthetic Fuels

    SciTech Connect (OSTI)

    Gormley, R.J.; Link, D.D.; Baltrus, J.P.; Zandhuis, P.H.

    2008-01-01

    A transition from petroleum-derived jet fuels to blends with Fischer-Tropsch (F-T) fuels, and ultimately fully synthetic hydro-isomerized F-T fuels has raised concern about the fate of plasticizers in nitrile-butadiene rubber o-rings that are contacted by the fuels as this transition occurs. The partitioning of plasticizers and fuel molecules between nitrile o-rings and petroleum-derived, synthetic, and additized-synthetic jet fuels has been measured. Thermal desorption of o-rings soaked in the various jet fuels followed by gas chromatographic analysis with a mass spectrometric detector showed many of the plasticizer and stabilizer compounds were removed from the o-rings regardless of the contact fuel. Fuel molecules were observed to migrate into the o-rings for the petroleum-derived fuel as did both the fuel and additive for a synthetic F-T jet fuel additized with benzyl alcohol, but less for the unadditized synthetic fuel. The specific compounds or classes of compounds involved in the partitioning were identified and a semiquantitative comparison of relative partitioning of the compounds of interest was made. The results provide another step forward in improving the confidence level of using additized, fuIly synthetic jet fuel in the place of petroleum-derived fueL

  19. Interactions of Jet Fuels with Nitrile O-Rings: Petroleum-Derived versus Synthetic Fuels

    SciTech Connect (OSTI)

    Gormley, R.J.; Link, D.D.; Baltrus, J.P.; Zandhuis, P.H.

    2009-01-01

    A transition from petroleum-derived jet fuels to blends with Fischer-Tropsch (F-T) fuels, and ultimately fully synthetic hydro-isomerized F-T fuels has raised concern about the fate of plasticizers in nitrile-butadiene rubber a-rings that are contacted by the fuels as this transition occurs. The partitioning of plasticizers and fuel molecules between nitrile a-rings and petroleum-derived, synthetic, and additized-synthetic jet fuels has been measured. Thermal desorption of o-rings soaked in the various jet fuels followed by gas chromatographic analysis with a mass spectrometric detector showed many of the plasticizer and stabilizer compounds were removed from the o-rings regardless of the contact fuel. Fuel molecules were observed to migrate into the o-rings for the petroleum-derived fuel as did both the fuel and additive for a synthetic F-T jet fuel additized with benzyl alcohol, but less for the unadditized synthetic fuel. The specific compounds or classes of compounds involved in the partitioning were identified and a semiquantitative comparison of relative partitioning of the compounds of interest was made. The results provide another step forward in improving the confidence level of using additized, fully synthetic jet fuel in the place of petroleum-derived fuel.

  20. Biological and Chemical Sciences Department of Biological and Chemical Sciences

    E-Print Network [OSTI]

    and Organic Materials Chromatography Regulatory Science Synthesis and Characterization of Inorganic Materials Synthesis and Characterization of Organic Materials Research Centers International Center for Sensor Science, microbiology, molecular biophysics and biochem- istry; analytical chemistry, inorganic chemistry, materi- als

  1. Arts & Sciences Biology, B.A.

    E-Print Network [OSTI]

    New Mexico, University of

    6/7/13 Arts & Sciences Biology, B.A. Broad Learning Goals A. Understand basic biological principles, and appreciate the breadth of modern biology. B. Understand and apply the scientific principle to conceptual or experimental problems in biology. C. Present biological data, and interpretations of the data, in written

  2. Modeling disease-related proteins in Saccharomyces cerevisiae : insights into alpha-synuclein and TorsinA biology

    E-Print Network [OSTI]

    Valastyan, Julie S. (Julie Suzanne)

    2013-01-01

    The yeast Saccharomyces cerevisiae has long been used to model complex cellular processes. As a eukaryote, much of its fundamental biology is conserved with higher organisms. As a single-celled, genetically tractable ...

  3. Loop Quantum Theory Applied to Biology and Nonlinear Whole Biology

    E-Print Network [OSTI]

    Yi-Fang Chang

    2008-01-02

    The loop quantum theory, which constitutes a very small discontinuous space, as new method is applied to biology. The model of protein folding and lungs is proposed. In the model, some known results are used, and four approximate conclusions are obtained: their structures are quantized, their space regions are finite, various singularities correspond to folding and crossed points, and different types of catastrophe exist. Further, based on the inseparability and correlativity of the biological systems, the nonlinear whole biology is proposed, and four basic hypotheses are formed. It may unify reductionism and holism, structuralism and functionalism. Finally, the medical meaning of the theory is discussed briefly.

  4. Organic binders for iron ore pelletization and steelmaking

    SciTech Connect (OSTI)

    Karkoska, D.; Sankey, E. [Allied Colloids, Suffolk, VA (United States); Anderson, R. [Eveleth Mines, MN (United States)

    1995-12-01

    Historically, bentonite has been used in the agglomeration process in North American iron ore plants. In 1986, Eveleth Mines replaced bentonite with Peridur, a carboxy methyl cellulose organic binder used in conjunction with 1% limestone. Since May of 1993, Allied Colloids` Alcotac FE8 has been used by Eveleth as the replacement for bentonite. This paper discusses the performance benefits obtained when bentonite was replaced with an organic binder. These totally synthetic binders are used in conjunction with limestone. The benefits of organic binders are: improved metallurgical parameters of the fired pellet, especially the reducibility, which results in more efficient use of gases in the blast furnace; reduced silica in the pellet, in the case of Eveleth Mines this was a reduction of 0.5%, a lower silica pellet reduces slag in the blast furnace; increased production in both the agglomeration/induration and steelmaking processes; and a decrease in coke consumption.

  5. Comparative Microbial Genomics group CenterforBiologicalSequenceanalysisDepartmentofSystemsBiology

    E-Print Network [OSTI]

    Ussery, David W.

    Comparative Microbial Genomics group CenterforBiologicalSequenceanalysisDepartmentofSystemsBiology Visualisation of Large Amounts of Data Dave Ussery 27 February, 2008 #12;Comparative Microbial Genomics group CenterforBiologicalSequenceanalysisDepartmentofSystemsBiology #12;Comparative Microbial Genomics group

  6. Thin film composition with biological substance and method of making

    DOE Patents [OSTI]

    Campbell, Allison A. (Kennewick, WA); Song, Lin (Richland, WA)

    1999-01-01

    The invention provides a thin-film composition comprising an underlying substrate of a first material including a plurality of attachment sites; a plurality of functional groups chemically attached to the attachment sites of the underlying substrate; and a thin film of a second material deposited onto the attachment sites of the underlying substrate, and a biologically active substance deposited with the thin-film. Preferably the functional groups are attached to a self assembling monolayer attached to the underlying substrate. Preferred functional groups attached to the underlying substrate are chosen from the group consisting of carboxylates, sulfonates, phosphates, optionally substituted, linear or cyclo, alkyl, alkene, alkyne, aryl, alkylaryl, amine, hydroxyl, thiol, silyl, phosphoryl, cyano, metallocenyl, carbonyl, and polyphosphate. Preferred materials for the underlying substrate are selected from the group consisting of a metal, a metal alloy, a plastic, a polymer, a proteic film, a membrane, a glass or a ceramic. The second material is selected from the group consisting of inorganic crystalline structures, inorganic amorphus structures, organic crystalline structures, and organic amorphus structures. Preferred second materials are phosphates, especially calcium phosphates and most particularly calcium apatite. The biologically active molecule is a protein, peptide, DNA segment, RNA segment, nucleotide, polynucleotide, nucleoside, antibiotic, antimicrobal, radioisotope, chelated radioisotope, chelated metal, metal salt, anti-inflamatory, steriod, nonsteriod anti-inflammatory, analgesic, antihistamine, receptor binding agent, or chemotherapeutic agent, or other biologically active material. Preferably the biologically active molecule is an osteogenic factor the compositions listed above.

  7. Thin film composition with biological substance and method of making

    SciTech Connect (OSTI)

    Campbell, A.A.; Song, L.

    1999-09-28

    The invention provides a thin-film composition comprising an underlying substrate of a first material including a plurality of attachment sites; a plurality of functional groups chemically attached to the attachment sites of the underlying substrate; and a thin film of a second material deposited onto the attachment sites of the underlying substrate, and a biologically active substance deposited with the thin-film. Preferably the functional groups are attached to a self assembling monolayer attached to the underlying substrate. Preferred functional groups attached to the underlying substrate are chosen from the group consisting of carboxylates, sulfonates, phosphates, optionally substituted, linear or cyclo, alkyl, alkene, alkyne, aryl, alkylaryl, amine, hydroxyl, thiol, silyl, phosphoryl, cyano, metallocenyl, carbonyl, and polyphosphate. Preferred materials for the underlying substrate are selected from the group consisting of a metal, a metal alloy, a plastic, a polymer, a proteic film, a membrane, a glass or a ceramic. The second material is selected from the group consisting of inorganic crystalline structures, inorganic amorphous structures, organic crystalline structures, and organic amorphous structures. Preferred second materials are phosphates, especially calcium phosphates and most particularly calcium apatite. The biologically active molecule is a protein, peptide, DNA segment, RNA segment, nucleotide, polynucleotide, nucleoside, antibiotic, antimicrobial, radioisotope, chelated radioisotope, chelated metal, metal salt, anti-inflammatory, steroid, nonsteroid anti-inflammatory, analgesic, antihistamine, receptor binding agent, or chemotherapeutic agent, or other biologically active material. Preferably the biologically active molecule is an osteogenic factor consisting of the compositions listed above.

  8. National Institutes of Health Training Program in Quantitative Biology and Physiology Rationale, Mission and Specific Aims of Training Program

    E-Print Network [OSTI]

    Vajda, Sandor

    scope of Systems Biology. Above the level of the cell, novel experimental imaging technologies (MRI, PET-cellular-tissue-organ) of a biological or physiological system or process. Our training program is motivated by fundamental challenges. At the scale of the cell and below, this information ranges from array technologies uncovering gene expression

  9. Tetratopic phenyl compounds, related metal-organic framework materials and post-assembly elaboration

    DOE Patents [OSTI]

    Farha, Omar K.; Hupp, Joseph T.

    2012-09-11

    Disclosed are tetratopic carboxylic acid phenyl for use in metal-organic framework compounds. These compounds are useful in catalysis, gas storage, sensing, biological imaging, drug delivery and gas adsorption separation.

  10. Tetratopic phenyl compounds, related metal-organic framework materials and post-assembly elaboration

    DOE Patents [OSTI]

    Farha, Omar K; Hupp, Joseph T

    2013-06-25

    Disclosed are tetratopic carboxylic acid phenyl for use in metal-organic framework compounds. These compounds are useful in catalysis, gas storage, sensing, biological imaging, drug delivery and gas adsorption separation.

  11. The Role of Spin for Kinetic Control of Recombination in Organic Photovoltaics

    E-Print Network [OSTI]

    Akshay, Rao; Philip C.Y., Chow; Gélinas, Simon; Schlenker, Cody W.; Li, Chang-Zhi; Yip, Hin-Lap; Jen, Alex K-Y.; Ginger, David S.; Friend, Richard H.

    2013-08-07

    In biological complexes, cascade structures promote the spatial separation of photogenerated electrons and holes, preventing their recombination. In contrast, the photogenerated excitons in organic photovoltaic cells are dissociated at a single...

  12. Teaching Organic Farming and Gardening: Resources for Instructors, 3rd Edition. Part 2 - Applied Soil Science

    E-Print Network [OSTI]

    2015-01-01

    Provides essential information on soil ecosystem managementexports to a soil ecosystem? What information would you needInformation-rich resource on soil organisms offers a comprehensive guide to soil biology, soil ecosystem

  13. Nearly Exclusive Growth of Small Diameter Semiconducting Single-Wall Carbon Nanotubes from Organic Chemistry Synthetic End-Cap

    E-Print Network [OSTI]

    Zhou, Chongwu

    spectroscopic characterization, electrical transport measurements, and density functional theory calculations for Energy and Resources, The University of Newcastle, Callaghan 2308, Australia WPI to achieve high-efficiency metal-free growth of nearly pure SWCNT semiconductors, as supported by extensive

  14. Biological and Environmental Research Network Requirements

    SciTech Connect (OSTI)

    Balaji, V.; Boden, Tom; Cowley, Dave; Dart, Eli; Dattoria, Vince; Desai, Narayan; Egan, Rob; Foster, Ian; Goldstone, Robin; Gregurick, Susan; Houghton, John; Izaurralde, Cesar; Johnston, Bill; Joseph, Renu; Kleese-van Dam, Kerstin; Lipton, Mary; Monga, Inder; Pritchard, Matt; Rotman, Lauren; Strand, Gary; Stuart, Cory; Tatusova, Tatiana; Tierney, Brian; Thomas, Brian; Williams, Dean N.; Zurawski, Jason

    2013-09-01

    The Energy Sciences Network (ESnet) is the primary provider of network connectivity for the U.S. Department of Energy (DOE) Office of Science (SC), the single largest supporter of basic research in the physical sciences in the United States. In support of SC programs, ESnet regularly updates and refreshes its understanding of the networking requirements of the instruments, facilities, scientists, and science programs that it serves. This focus has helped ESnet be a highly successful enabler of scientific discovery for over 25 years. In November 2012, ESnet and the Office of Biological and Environmental Research (BER) of the DOE SC organized a review to characterize the networking requirements of the programs funded by the BER program office. Several key findings resulted from the review. Among them: 1) The scale of data sets available to science collaborations continues to increase exponentially. This has broad impact, both on the network and on the computational and storage systems connected to the network. 2) Many science collaborations require assistance to cope with the systems and network engineering challenges inherent in managing the rapid growth in data scale. 3) Several science domains operate distributed facilities that rely on high-performance networking for success. Key examples illustrated in this report include the Earth System Grid Federation (ESGF) and the Systems Biology Knowledgebase (KBase). This report expands on these points, and addresses others as well. The report contains a findings section as well as the text of the case studies discussed at the review.

  15. Rank 1995-96 1996-97 1997-98 1998-99 1999-00 2000-01 2001-02 2002-03 2003-04 1 Biological Sciences Biological Sciences Biological Sciences Biological Sciences Biological Sciences Biological Sciences Biological Sciences Biological Sciences Biological Scien

    E-Print Network [OSTI]

    Ullrich, Paul

    Engineering Sociology 3 Sociology 3 Animal Science Animal Science Biochemistry Animal Science Biochem Biological Sciences Biological Sciences Biological Sciences 2 Biochemistry Biochemistry Biochemistry Economics 4 Political Science 2 Political Science 2 Human Development Biochemistry Biochemistry Political

  16. The new biology: beyond the Modern Synthesis

    E-Print Network [OSTI]

    Rose, Michael R; Oakley, Todd H

    2007-01-01

    The Evolution of Biology. New York: Oxford University Press;2003. Woese CR: A new biology for a new century. Microbiol1961, 5:. Comfort A: The biology of senescence. 3rd edition.

  17. Monte Carlo simulation in systems biology

    E-Print Network [OSTI]

    Schellenberger, Jan

    2010-01-01

    2 The history of Monte Carlo Sampling in Systems Biology 1.1simulation tools: the systems biology workbench and biospiceCellular and Molecular Biology. ASM Press, Washington

  18. Engineering supported membranes for cell biology

    E-Print Network [OSTI]

    Yu, Cheng-han; Groves, Jay T.

    2010-01-01

    membranes in structural biology. J Struct Biol 168:1–2 50.supported membranes for cell biology Cheng-han Yu • Jay T.range problems in cell biology. Because lateral mobility of

  19. Noah A. Rosenberg Department of Biology

    E-Print Network [OSTI]

    Rosenberg, Noah

    Noah A. Rosenberg Department of Biology Stanford University Stanford, CA 94305-5020 USA (650) 721 appointments 2011- Associate Professor, Department of Biology, Stanford University 2009-2011 Associate Professor, Departments of Human Genetics, Ecology & Evolutionary Biology, and Biostatistics, University

  20. THE BUREAU OF COMMERCIAL FISHERIES BIOLOGICAL LABORATORY

    E-Print Network [OSTI]

    THE BUREAU OF COMMERCIAL FISHERIES BIOLOGICAL LABORATORY OXFORD, MARYLAND: PROGRAMS OF COMMERCIAL FISHERIES BIOLOGICAL LABORATORY OXFORD, MARYLAND: PROGRAMS AND PERSPECTIVES Circular 200 Washington, D.C. October 1964 #12;Cover Photo: The Bureau of Commercial Fisheries Biological Laboratory

  1. Mixed crystal organic scintillators

    DOE Patents [OSTI]

    Zaitseva, Natalia P; Carman, M Leslie; Glenn, Andrew M; Hamel, Sebastien; Hatarik, Robert; Payne, Stephen A; Stoeffl, Wolfgang

    2014-09-16

    A mixed organic crystal according to one embodiment includes a single mixed crystal having two compounds with different bandgap energies, the organic crystal having a physical property of exhibiting a signal response signature for neutrons from a radioactive source, wherein the signal response signature does not include a significantly-delayed luminescence characteristic of neutrons interacting with the organic crystal relative to a luminescence characteristic of gamma rays interacting with the organic crystal. According to one embodiment, an organic crystal includes bibenzyl and stilbene or a stilbene derivative, the organic crystal having a physical property of exhibiting a signal response signature for neutrons from a radioactive source.

  2. Developing Biological Specifications for Fish Friendly Turbines...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Developing Biological Specifications for Fish Friendly Turbines Developing Biological Specifications for Fish Friendly Turbines This factsheet explains studies conducted in a...

  3. The sequestration efficiency of the biological pump

    E-Print Network [OSTI]

    DeVries, Tim; Primeau, Francois; Deutsch, Curtis

    2012-01-01

    Preformed phosphate, soft tissue pump and atmospheric CO 2 ,efficiency of the biological pump Tim DeVries, 1 Francoisproduces a “biological pump” that reduces the concentration

  4. Computational biology and high performance computing

    E-Print Network [OSTI]

    Shoichet, Brian

    2011-01-01

    Biology and High Performance Computing Manfred Zorn, TeresaBiology and High Performance Computing Presenters: Manfred99-Portland High performance computing has become one of the

  5. Chemistry & Biology Deciphering the Late Biosynthetic Steps

    E-Print Network [OSTI]

    Zhao, Huimin

    Chemistry & Biology Article Deciphering the Late Biosynthetic Steps of Antimalarial Compound FR Engineering 2Institute for Genomic Biology 3Department of Microbiology 4Department of Chemistry 5Departments

  6. Renewable Hydrogen Production from Biological Systems

    Broader source: Energy.gov (indexed) [DOE]

    Hydrogen Production from Biological Systems Matthew Posewitz Colorado School of Mines DOE Biological Hydrogen Production Workshop September 24 th , 2013 H 2 production PSIIPSI...

  7. DEPARTMENT OF BIOLOGY Hurricane Savitz Hits Florida

    E-Print Network [OSTI]

    Kelly, John J.

    DEPARTMENT OF BIOLOGY Hurricane Savitz Hits Florida (Photo Credit: Michael Masellis, Biology Major Hurricane Savitz Hits Florida Future Science Teachers' Club Recent Grant Successes Forthcoming Publications

  8. Architecture & Civil Engineering Biology & Biochemistry

    E-Print Network [OSTI]

    Burton, Geoffrey R.

    Department Architecture & Civil Engineering Biology & Biochemistry Chemical Engineering Chemistry Computer Science Economics Education Electronic & Electrical Engineering Department Health Management Mathematical Sciences Mechanical Engineering Natural Sciences (please go to the Info Fair ­ no staff in office

  9. BIOLOGICAL ENGINEERING Program of Study

    E-Print Network [OSTI]

    Thomas, Andrew

    The Master of Science in Biological Engineering prepares students to conduct research involving Professor. Conformation of interfacial species, surface spectroscopies/microscopies, binary polymer Sciences. Composites, coating layer mechanical properties. Barbara J. W. Cole, Ph.D. (Washington, 1986

  10. Preparing for Transfer Biological Engineering

    E-Print Network [OSTI]

    Walter, M.Todd

    Preparing for Transfer Majors: Biological Engineering Chemical Engineering Civil Engineering Computer Science Electrical & Computer Engineering Engineering Physics Environmental Engineering Information Science, Systems, & Technology Materials Science & Engineering Mechanical Engineering Operations

  11. Preparing for Transfer Biological Engineering

    E-Print Network [OSTI]

    Walter, M.Todd

    Preparing for Transfer Majors: Biological Engineering Biomedical Engineering* Chemical Engineering Civil Engineering Computer Science Electrical & Computer Engineering Engineering Physics Environmental Engineering Information Science, Systems, & Technology Materials Science & Engineering Mechanical Engineering

  12. Modular design of biological systems

    E-Print Network [OSTI]

    Norville, Julie Erin, 1980-

    2012-01-01

    The focus of my research is the development of technology for building compound biological systems from simpler pieces. I designed BioScaffold parts, a family of variable regions that can be inserted into a DNA sequence ...

  13. ADVANCEMENT COUNCIL Department of Biology

    E-Print Network [OSTI]

    Chalcraft, David R.

    Institute Mark Philips, B.S. North Carolina Biotechnology Center Francis J. Reilly, Jr. Ph.D. Logistics Management Institute Bobby J. Ward, Ph. D. Retired, CP&L Biologues A Newsletter of the Department of Biology

  14. Method for biological purification

    DOE Patents [OSTI]

    Lucido, John A. (Mt. Sinai, NY); Keenan, Daniel (Rockville Centre, NY); Premuzic, Eugene T. (East Moriches, NY); Lin, Mow S. (Rocky Point, NY); Shelenkova, Ludmila (Yaphank, NY)

    2001-03-27

    An apparatus is disclosed for containing a microorganism culture in an active exponential growth and delivering a supply of microorganisms to an environment containing wastes for bio-augmenting the biodegradation of the wastes. The apparatus comprises a bioreactor and an operably connected controller. The bioreactor has a bioreactor chamber for containing a supply of microorganisms, a second chamber for containing a supply of water and inorganic nutrients, and a third chamber for containing a supply of organic nutrients. The bioreactor is operably connected to the controller in which a first pump is operably connected in fluid communication between the bioreactor chamber and the second chamber and third chamber, and a second pump is operably connected in fluid communication between the bioreactor chamber and the environment containing wastes to be biodegraded. The controller further includes a timer and regulator operably connected to the first and second pumps to effectively maintain the microorganisms in exponential growth in the bioreactor chamber and to deliver microorganisms to an environment to be treated. Also, disclosed is a method for bio-augmenting the biodegradation of wastes.

  15. Organic photovoltaics and concentrators

    E-Print Network [OSTI]

    Mapel, Jonathan King

    2008-01-01

    The separation of light harvesting and charge generation offers several advantages in the design of organic photovoltaics and organic solar concentrators for the ultimate end goal of achieving a lower cost solar electric ...

  16. Organic photosensitive devices

    DOE Patents [OSTI]

    Rand, Barry P; Forrest, Stephen R

    2013-11-26

    The present invention generally relates to organic photosensitive optoelectronic devices. More specifically, it is directed to organic photosensitive optoelectronic devices having a photoactive organic region containing encapsulated nanoparticles that exhibit plasmon resonances. An enhancement of the incident optical field is achieved via surface plasmon polariton resonances. This enhancement increases the absorption of incident light, leading to a more efficient device.

  17. The Science Institutes at Yale's West Campus Chemical Biology Cancer Biology Energy Sciences Microbial Diversity Nanobiology Systems Biology

    E-Print Network [OSTI]

    The Science Institutes at Yale's West Campus Chemical Biology Cancer Biology Energy Sciences Microbial Diversity Nanobiology Systems Biology The Chemical Biology Institute at Yale's West Campus #12 and molecular assem- blies, large and small, to address challenging problems in health, energy

  18. Introduction It is well established that dissolved organic matter (DOM)

    E-Print Network [OSTI]

    Boss, Emmanuel S.

    weeks or more, with the frequency and duration limited only by power consumption and data storage in biogeochemical processes: it supplies energy to heterotrophic organisms, binds metals and pesti- cides, affects may rapidly change in response to aperiodic as well as periodic physi- cal and biological forcing

  19. Effect of 1-hydroxyethane-1,1-diphosphonic acid (HEDPA) on Partitioning of Np and Pu to Synthetic Boehmite

    E-Print Network [OSTI]

    Powell, Brian A.

    2010-01-01

    of plutonium IV and V on goethite. Geochim. Cosmo. Acta,reduction on synthetic goethite (?-FeOOH) and hematite (?-Fe

  20. Vehicle Technologies Office Merit Review 2014: Synthetic Solutions for Correcting Voltage Fade in LMR-NMC Cathodes

    Broader source: Energy.gov [DOE]

    Presentation given by Argonne National Laboratory at 2014 DOE Hydrogen and Fuel Cells Program and Vehicle Technologies Office Annual Merit Review and Peer Evaluation Meeting about synthetic...

  1. A bio-synthetic interface for discovery of viral entry mechanisms.

    SciTech Connect (OSTI)

    Gutzler, Mike; Maar, Dianna; Negrete, Oscar; Hayden, Carl C.; Sasaki, Darryl Yoshio; Stachowiak, Jeanne C.; Wang, Julia

    2010-09-01

    Understanding and defending against pathogenic viruses is an important public health and biodefense challenge. The focus of our LDRD project has been to uncover the mechanisms enveloped viruses use to identify and invade host cells. We have constructed interfaces between viral particles and synthetic lipid bilayers. This approach provides a minimal setting for investigating the initial events of host-virus interaction - (i) recognition of, and (ii) entry into the host via membrane fusion. This understanding could enable rational design of therapeutics that block viral entry as well as future construction of synthetic, non-proliferating sensors that detect live virus in the environment. We have observed fusion between synthetic lipid vesicles and Vesicular Stomatitis virus particles, and we have observed interactions between Nipah virus-like particles and supported lipid bilayers and giant unilamellar vesicles.

  2. SINGLE MOLECULE APPROACHES TO BIOLOGY, 2010 GORDON RESEARCH CONFERENCE, JUNE 27-JULY 2, 2010, ITALY

    SciTech Connect (OSTI)

    Professor William Moerner

    2010-07-09

    The 2010 Gordon Conference on Single-Molecule Approaches to Biology focuses on cutting-edge research in single-molecule science. Tremendous technical developments have made it possible to detect, identify, track, and manipulate single biomolecules in an ambient environment or even in a live cell. Single-molecule approaches have changed the way many biological problems are addressed, and new knowledge derived from these approaches continues to emerge. The ability of single-molecule approaches to avoid ensemble averaging and to capture transient intermediates and heterogeneous behavior renders them particularly powerful in elucidating mechanisms of biomolecular machines: what they do, how they work individually, how they work together, and finally, how they work inside live cells. The burgeoning use of single-molecule methods to elucidate biological problems is a highly multidisciplinary pursuit, involving both force- and fluorescence-based methods, the most up-to-date advances in microscopy, innovative biological and chemical approaches, and nanotechnology tools. This conference seeks to bring together top experts in molecular and cell biology with innovators in the measurement and manipulation of single molecules, and will provide opportunities for junior scientists and graduate students to present their work in poster format and to exchange ideas with leaders in the field. A number of excellent poster presenters will be selected for short oral talks. Topics as diverse as single-molecule sequencing, DNA/RNA/protein interactions, folding machines, cellular biophysics, synthetic biology and bioengineering, force spectroscopy, new method developments, superresolution imaging in cells, and novel probes for single-molecule imaging will be on the program. Additionally, the collegial atmosphere of this Conference, with programmed discussion sessions as well as opportunities for informal gatherings in the afternoons and evenings in the beauty of the Il Ciocco site in Tuscany, provides an avenue for scientists from different disciplines to interact and brainstorm and promotes cross-disciplinary collaborations directed toward compelling biological problems.

  3. Synthesis and Characterization of Porphyrin Containing Metal-Organic Frameworks /

    E-Print Network [OSTI]

    Butler, Derek Prescott

    2013-01-01

    synthetic modifications (PSM) methods, such as by removal ofPost synthetic modification (PSM) of the prefabricated solidthat do not require extensive PSM techniques to activate the

  4. 2012 CELLULAR & MOLECULAR FUNGAL BIOLOGY GORDON RESEARCH CONFERENCE, JUNE 17 - 22, 2012

    SciTech Connect (OSTI)

    Judith Berman

    2012-06-22

    The Gordon Research Conference on CELLULAR & MOLECULAR FUNGAL BIOLOGY was held at Holderness School, Holderness New Hampshire, June 17 - 22, 2012. The 2012 Gordon Conference on Cellular and Molecular Fungal Biology (CMFB) will present the latest, cutting-edge research on the exciting and growing field of molecular and cellular aspects of fungal biology. Topics will range from yeast to filamentous fungi, from model systems to economically important organisms, and from saprophytes and commensals to pathogens of plants and animals. The CMFB conference will feature a wide range of topics including systems biology, cell biology and morphogenesis, organismal interactions, genome organisation and regulation, pathogenesis, energy metabolism, biomass production and population genomics. The Conference was well-attended with 136 participants. Gordon Research Conferences does not permit publication of meeting proceedings.

  5. Emissions from Buses with DDC 6V92 Engines Using Synthetic Diesel Fuel

    SciTech Connect (OSTI)

    Paul Norton; Keith Vertin; Nigel N. Clark; Donald W. Lyons; Mridul Gautam; Stephen Goguen; James Eberhardt

    1999-05-03

    Synthetic diesel fuel can be made from a variety of feedstocks, including coal, natural gas and biomass. Synthetic diesel fuels can have very low sulfur and aromatic content, and excellent autoignition characteristics. Moreover, synthetic diesel fuels may also economically competitive with California diesel fuel if .roduced in large volumes. Previous engine laboratory and field tests using a heavy-duty chassis dynamometer indicate that synthetic diesel fuel made using the Fischer-Tropsch (F-T) catalytic conversion process is a promising alternative fuel, because it can be used in unmodified diesel engines, and can reduce exhaust emissions substantially. The objective of this study was a preliminary assessment of the emissions from older model transit operated on Mossgas synthetic diesel fuel. The study compared emissions from transit buses operating on Federal no. 2 Diesel fuel, Mossgas synthetic diesel (MGSD), and a 50/50 blend of the two fuels. The buses were equipped with unmodified Detroit Diesel 6V92 2-stroke diesel engines. Six 40-foot buses were tested. Three of the buses had recently rebuilt engines and were equipped with an oxidation catalytic converter. Vehicle emissions measurements were performed using West Virginia University's unique transportable chassis dynamometer. The emissions were measured over the Central Business District (CBD) driving cycle. The buses performed well on both neat and blended MGSD fuel. Three buses without catalytic converters were tested. Compared to their emissions when operating on Federal no. 2 diesel fuel, these buses emitted an average of 5% lower oxides of nitrogen (NOx) and 20% lower particulate matter (PM) when operating on neat MGSD fuel. Catalyst equipped buses emitted an average of 8% lower NOx and 31% lower PM when operating on MGSD than when operating on Federal no. 2 diesel fuel.

  6. Petri net modelling of biological Claudine Chaouiya

    E-Print Network [OSTI]

    Breitling, Rainer

    Petri net modelling of biological networks Claudine Chaouiya Submitted: 31st March 2007; Received into the functioning of complex biological networks. In this context, Petri nets (PNs) have recently emerged of the computational systems biology. Keywords: dynamical modelling; Petri nets; biological networks INTRODUCTION

  7. MASTER OF SCIENCE STUDIES IN BIOLOGY

    E-Print Network [OSTI]

    Hong, Don

    Ver. 1.15 MASTER OF SCIENCE STUDIES IN BIOLOGY GUIDE FOR APPLICANTS, GRADUATE STUDENTS AND GRADUATE Biology and Ecology Physiology and Cellular/Molecular Biology Research Tools COURSE LOADS AND RECOMMENDED.......................................................................................................................................12 Change of Thesis Advisor Registration for Biological Research Thesis Proposal Registration

  8. Supplemental Graduate Application DEPARTMENT OF BIOLOGY

    E-Print Network [OSTI]

    Hamburger, Peter

    Supplemental Graduate Application DEPARTMENT OF BIOLOGY INDIANA UNIVERSITY-PURDUE UNIVERSITY FORT: ______________________ To assist with processing your application please fill out and submit this form to biology For questions, please refer to the Biology Graduate Programs Handbook or contact the Biology Graduate Program

  9. Biology Advising Office Building 44, Room 135

    E-Print Network [OSTI]

    Clayton, Dale H.

    Biology Advising Office Building 44, Room 135 Mailing Address: Biology Advising Office, University of Utah, 257 South 1400 East, Salt Lake City, Utah 84112-0840 http://www.biology.utah.edu/undergraduate/advising.php Email: advising@biology.utah.edu Phone: (801) 581-6244 Fax: (801) 581-8571 Denise M. Brenis, Director

  10. Plant & Microbial Biology Spring 2012 Seminar Series

    E-Print Network [OSTI]

    Wildermuth, Mary C

    Lovley Department of Microbial Biology | University of Massachusetts, Amherst "Artificial Photosynthesis

  11. Synthetic Hexaploid Wheat as a Source of Improvement for Winter Wheat (Triticum aestivum L.) in Texas 

    E-Print Network [OSTI]

    Cooper, Jessica Kay

    2012-02-14

    backcrosses to spring wheats show improvement over recurrent parents (del Blanco et al., 2000; Lage et al., 2004a; Mujeeb-Kazi et al., 2008; Villareal et al., 1994) but evidence of the benefits of synthetic backcrosses to winter wheat is meager... drought stress, a common problem in Texas High Plains, as well as heat stress, a common problem in South Texas (del Blanco et al., 2000; Reynolds et al., 2007; Trethowanand Mujeeb-Kazi, 2008). Reynolds et al. attributed synthetic lines to be better...

  12. Synthetic peptides that cause F-actin bundling and block actin depolymerization

    DOE Patents [OSTI]

    Sederoff, Heike (Raleigh, NC); Huber, Steven C (Savoy, IL); Larabell, Carolyn A (Berkeley, CA)

    2011-10-18

    Synthetic peptides derived from sucrose synthase, and having homology to actin and actin-related proteins, sharing a common motif, useful for causing acting bundling and preventing actin depolymerization. Peptides exhibiting the common motif are described, as well as specific synthetic peptides which caused bundled actin and inhibit actin depolymerization. These peptides can be useful for treating a subject suffering from a disease characterized by cells having neoplastic growth, for anti-cancer therapeutics, delivered to subjects solely, or concomitantly or sequentially with other known cancer therapeutics. These peptides can also be used for stabilizing microfilaments in living cells and inhibiting growth of cells.

  13. Biology 2250 Principles of Genetics

    E-Print Network [OSTI]

    Innes, David J.

    in genetics (GMO, gene therapy...) What is Genetics ? - Genetics is the study of heredity and variation in Genetics · Genetically modified organisms (GMO) · Gene therapy (Parkinson's) http

  14. Environment Assisted Quantum Transport in Organic Molecules

    E-Print Network [OSTI]

    Vattay, Gabor

    2015-01-01

    One of the new discoveries in quantum biology is the role of Environment Assisted Quantum Transport (ENAQT) in excitonic transport processes. In disordered quantum systems transport is most efficient when the environment just destroys quantum interferences responsible for localization, but the coupling does not drive the system to fully classical thermal diffusion yet. This poised realm between the pure quantum and the semi-classical domains has not been considered in other biological transport processes, such as charge transport through organic molecules. Binding in receptor-ligand complexes is assumed to be static as electrons are assumed to be not able to cross the ligand molecule. We show that ENAQT makes cross ligand transport possible and efficient between certain atoms opening the way for the reorganization of the charge distribution on the receptor when the ligand molecule docks. This new effect can potentially change our understanding how receptors work. We demonstrate room temperature ENAQT on the c...

  15. Preparation and synthetic application of {alpha}-phenylthioethylsamarium compound

    SciTech Connect (OSTI)

    Kasuga, Y.; Matsubara, S.; Utimoto, K. [Kyoto Univ. (Japan)

    1995-12-31

    Although samarium(II) iodide-mediated reaction of organohalides with carbonyl compounds has been applied to various organic syntheses, intermediary organosamarium species could be detected only when HMPA exists in the reaction system. The authors now report the detection of {alpha}-phenylthioethylsamarium compound in the absence of HMPA and application to diastereoselective reaction with aldehydes. A treatment of the organosamarium reagent, prepared from 1-chloroethyl phenyl sulfide and samarium(II) iodide, with D{sub 2}O afforded 1-deuterioethyl phenyl sulfide in 53% yield (82% D). The reagent reacted with aldehyde containing a stereogenic center at {alpha}-position to give {beta}-hydroxysulfide with high diastereoselectivity. Reaction using Barbier type procedure afforded the same results. These results suggest that {alpha}-phenylthioethylsamarium species is also generated in the Barbier type reaction. Configurational stability of {alpha}-thiosubstituted alkylmetal compounds seems to depend on the applied metal. Hoffmann Test indicated that the configuration of {alpha}-phenylthloethylsamarium compound is unchanged during the reaction with aldehyde, while that of {alpha}-alkylthioalkyllithium is unstable.

  16. Glassy dynamics distinguishes chromosome organization across organisms

    E-Print Network [OSTI]

    Hongsuk Kang; Young-Gui Yoon; D. Thirumalai; Changbong Hyeon

    2015-06-03

    Recent experiments showing scaling of the intrachromosomal contact probability, $P(s)\\sim s^{-1}$ with the genomic distance $s$, are interpreted to mean a self-similar fractal-like chromosome organization. However, scaling of $P(s)$ varies across organisms, requiring an explanation. We illustrate that dynamical arrest in a highly confined space as a discriminating marker for genome organization, by modeling chromosome inside a nucleus as a self-avoiding homopolymer confined to a sphere of varying sizes. Brownian dynamics simulations show that the chain dynamics slows down as the polymer volume fraction ($\\phi$) inside the confinement approaches a critical value $\\phi_c$. Using finite size scaling analysis, we determine $\\phi_c^{\\infty}\\approx 0.44$ for a sufficiently long polymer ($N\\gg 1$). Our study shows that the onset of glassy dynamics is the reason for the formation of segregated organization in human chromosomes ($N\\approx 3\\times 10^9$, $\\phi\\gtrsim\\phi_c^{\\infty}$), whereas chromosomes of budding yeast ($N\\approx 1.2\\times 10^7$, $\\phi<\\phi_c^{\\infty}$) are equilibrated with no clear signature of such organization.

  17. Elliott J Blumenthal-Biology Lead Advisor and Associate Chair-Biology

    E-Print Network [OSTI]

    Hamburger, Peter

    Elliott J Blumenthal- Biology Lead Advisor and Associate Chair- Biology Frank V Paladino- Chair, Department of Biology #12;Objectives for Orientation today To give a description of the Biology Program To give an overview of the various "CONCENTRATIONS" that are available for majors in Biology To describe

  18. Biology BS, Environmental Biology Emphasis, 2015-2016 Name ID# Date

    E-Print Network [OSTI]

    Barrash, Warren

    Biology BS, Environmental Biology Emphasis, 2015-2016 Name ID# Date Course Number and Title Credits 170 4 DLN BIOL 191 General Biology I 4 DLN CHEM 111, 111L General Chemistry I with Lab 4 DLV Visual Sciences course in a second field 3 BIOL 192 General Biology II 4 BIOL 301 Cell Biology 3 CID BIOL 323

  19. 6/06/09 BA in General Biology Bachelor of Arts in General Biology

    E-Print Network [OSTI]

    6/06/09 BA in General Biology Bachelor of Arts in General Biology Department of Biology College of Science and Engineering Undergraduate Programs Students majoring in the General Biology degree program are required to complete 57 units in the major. In addition to the biological science courses, it includes

  20. Biology BS, Human Biology Emphasis, 2015-2016 Name ID# Date

    E-Print Network [OSTI]

    Barrash, Warren

    Biology BS, Human Biology Emphasis, 2015-2016 Name ID# Date Course Number and Title Credits 170 4 DLN BIOL 191 General Biology I 4 DLN CHEM 111, 111L General Chemistry I with Lab 4 DLV Visual Sciences course in a second field 3 BIOL 192 General Biology II 4 BIOL 301 Cell Biology 3 CID BIOL 323

  1. Systems biology approach to bioremediation

    SciTech Connect (OSTI)

    Chakraborty, R.; Wu, C. H.; Hazen, T. C.

    2012-01-01

    Bioremediation has historically been approached as a ?black box? in terms of our fundamental understanding. Thus it succeeds and fails, seldom without a complete understanding of why. Systems biology is an integrated research approach to study complex biological systems, by investigating interactions and networks at the molecular, cellular, community, and ecosystem level. The knowledge of these interactions within individual components is fundamental to understanding the dynamics of the ecosystem under investigation. Understanding and modeling functional microbial community structure and stress responses in environments at all levels have tremendous implications for our fundamental understanding of hydrobiogeochemical processes and the potential for making bioremediation breakthroughs and illuminating the ?black box?.

  2. Organic photosensitive devices

    DOE Patents [OSTI]

    Peumans, Peter; Forrest, Stephen R.

    2013-01-22

    A photoactive device is provided. The device includes a first electrode, a second electrode, and a photoactive region disposed between and electrically connected to the first and second electrodes. The photoactive region further includes an organic donor layer and an organic acceptor layer that form a donor-acceptor heterojunction. The mobility of holes in the organic donor region and the mobility of electrons in the organic acceptor region are different by a factor of at least 100, and more preferably a factor of at least 1000. At least one of the mobility of holes in the organic donor region and the mobility of electrons in the organic acceptor region is greater than 0.001 cm.sup.2/V-sec, and more preferably greater than 1 cm.sup.2/V-sec. The heterojunction may be of various types, including a planar heterojunction, a bulk heterojunction, a mixed heterojunction, and a hybrid planar-mixed heterojunction.

  3. Nonlinear organic plasmonics

    E-Print Network [OSTI]

    Fainberg, B D

    2015-01-01

    Purely organic materials with negative and near-zero dielectric permittivity can be easily fabricated. Here we develop a theory of nonlinear non-steady-state organic plasmonics with strong laser pulses. The bistability response of the electron-vibrational model of organic materials in the condensed phase has been demonstrated. Non-steady-state organic plasmonics enable us to obtain near-zero dielectric permittivity during a short time. We have proposed to use non-steady-state organic plasmonics for the enhancement of intersite dipolar energy-transfer interaction in the quantum dot wire that influences on electron transport through nanojunctions. Such interactions can compensate Coulomb repulsions for particular conditions. We propose the exciton control of Coulomb blocking in the quantum dot wire based on the non-steady-state near-zero dielectric permittivity of the organic host medium.

  4. A Synthetic Carotenoid Pathway We designed a 8400 nucleotide DNA sequence to encode the seven crt enzymes

    E-Print Network [OSTI]

    Maranas, Costas

    RNA to the free energy change Gtot according to: Predictive Design of Synthetic Microbes 1Pennsylvania State a synthetic gene network that combines cell-to-cell communication with logical cellular computing to execute into a microbial host enables the production of fuels, specialty chemicals, and drugs from renewable feedstocks

  5. 57106 Federal Register / Vol. 78, No. 180 / Tuesday, September 17, 2013 / Proposed Rules for lead in synthetic iron oxide for

    E-Print Network [OSTI]

    proposes to lower the specification limit for lead in synthetic iron oxide for human food use from 1057106 Federal Register / Vol. 78, No. 180 / Tuesday, September 17, 2013 / Proposed Rules for lead in synthetic iron oxide for human food use. DATES: The color additive petition was filed on July 16, 2013

  6. Active control of passive acoustic fields: Passive synthetic apertureDoppler beamforming with data from an autonomous

    E-Print Network [OSTI]

    Smith, Jerome A.

    Active control of passive acoustic fields: Passive synthetic apertureÕDoppler beamforming with data without the use of an active source under control by the receiver. In this passive case, the properties interest. Passive synthetic aperture sonar has no ana- log in the radar community. In contrast

  7. Analyzing Chinese Synthetic Words with Tree-based Information and a Survey on Chinese Morphologically Derived Words

    E-Print Network [OSTI]

    Analyzing Chinese Synthetic Words with Tree-based Information and a Survey on Chinese and Technology matsu@is.naist.jp Abstract The lack of internal information of Chinese synthetic words has become a crucial prob- lem for Chinese morphological analysis sys- tems which will face various needs of seg

  8. A thin layer of phytoplankton observed in the Philippine Sea with a synthetic moored array of autonomous gliders

    E-Print Network [OSTI]

    Fratantoni, David

    A thin layer of phytoplankton observed in the Philippine Sea with a synthetic moored array and phytoplankton distribution in a 100 km  100 km domain in the Philippine Sea east of Luzon Strait for 10 days), A thin layer of phytoplankton observed in the Philippine Sea with a synthetic moored array of autonomous

  9. Ion-beam and electron-beam irradiation of synthetic britholite S. Utsunomiya a

    E-Print Network [OSTI]

    Utsunomiya, Satoshi

    Ion-beam and electron-beam irradiation of synthetic britholite S. Utsunomiya a , S. Yudintsev b , L ). The sequence of increasing Tc correlates with the mass of the incident ion; whereas, the ratio of electronic to nuclear stopping power (ENSP) is inversely correlated with Tc. Electron irradiations were conducted

  10. Basics of Polar-Format algorithm for processing Synthetic Aperture Radar images.

    SciTech Connect (OSTI)

    Doerry, Armin Walter

    2012-05-01

    The purpose of this report is to provide a background to Synthetic Aperture Radar (SAR) image formation using the Polar Format (PFA) processing algorithm. This is meant to be an aid to those tasked to implement real-time image formation using the Polar Format processing algorithm.

  11. Modeling Wildland Fire Radiance in Synthetic Remote Sensing B.S. Beijing Institute of Technology, 1996

    E-Print Network [OSTI]

    Salvaggio, Carl

    efforts in phenomenology studies, algorithm development, and sensor evaluation. Synthetic scenes are also and op- tical properties of wildfire and burn area in an infrared remote sensing system will assist look like as seen by the airborne sensor. Radiance scene rendering of the 3D flame iv #12;v includes 2D

  12. Ris-PhD-27(EN) Wind Energy Applications of Synthetic

    E-Print Network [OSTI]

    winds in offshore wind resource assessment. Firstly, wind wakes behind two large offshore wind farms farming 3 2.1 Horns Rev and Nysted offshore wind farms 4 3 Synthetic aperture radar 6 3.1 Imaging geometry in offshore wind energy planning as a supplement to on site measurements, which are costly and sparse

  13. Seasonal subsidence and rebound in Las Vegas Valley, Nevada, observed by synthetic aperture radar interferometry

    E-Print Network [OSTI]

    Amelung, Falk

    Seasonal subsidence and rebound in Las Vegas Valley, Nevada, observed by synthetic aperture radar in the subsidence and rebound occurring over stressed aquifer systems, in conjunction with measurements, generally permanent aquifer system compaction and land subsidence at yearly and longer timescales, caused

  14. Synthetic Humans in Emergency Response Drills Daniel Massaguer, Vidhya Balasubramanian, Sharad Mehrotra, and Nalini Venkatasubramanian

    E-Print Network [OSTI]

    Venkatasubramanian, Nalini

    Synthetic Humans in Emergency Response Drills Daniel Massaguer, Vidhya Balasubramanian, Sharad demonstrates a concrete model for evacuations integrated with an emergency drill simulation environment this information to make decisions. The decision-making model is tested and calibrated with an emergency drill

  15. Laminar Flame Speed Measurments of Synthetic Gas Blends with Hydrocarbon Impurities 

    E-Print Network [OSTI]

    Keesee, Charles Lewis

    2015-04-09

    New laminar flame speed measurements have been taken for a wide range of synthetic gas, or syngas, mixtures. These experiments began with two baseline mixtures. The first of these baseline mixtures was a bio-syngas surrogate with a 50/50 H2/CO split...

  16. SYNTHETIC APERTURE INVERSION FOR NON-FLAT TOPOGRAPHY C. J. Nolan *

    E-Print Network [OSTI]

    Cheney, Margaret

    SYNTHETIC APERTURE INVERSION FOR NON-FLAT TOPOGRAPHY C. J. Nolan * , M. Cheney ** * Department topography is known but not necessarily flat. We consider two cases, corresponding to the degree and the topography to avoid artifacts. We show that the algorithm correctly reproduces certain features of the scene

  17. Ion Irradiation Effects in Synthetic Garnets Incorporating Actinides Satoshi Utsunomiya1

    E-Print Network [OSTI]

    Utsunomiya, Satoshi

    Ion Irradiation Effects in Synthetic Garnets Incorporating Actinides Satoshi Utsunomiya1 , Lu.0 MeV Kr2+ irradiation with in situ transmission electron microscopy over the temperature range of 50 the long term radiation effects due to radioactive decay can be simulated in short term with heavy ion-irradiation

  18. Intelligent Agents for the Synthetic Battlefield: A Company of Rotary Wing Aircraft

    E-Print Network [OSTI]

    Gratch, Jonathan

    agents that perform the tasks of an attack helicopter company for a synthetic battlefield environment to develop: (1) pilot agents for a company of helicopters, (2) a command agent that makes decisions and plans for the helicopter company, and (3) an approach to teamwork that enables the pilot agents to coordinate

  19. Stochastic Generation of Synthetic Precipitation Time Series with High Temporal and Spatial Resolution for Engineering Practice

    E-Print Network [OSTI]

    Cirpka, Olaf Arie

    Stochastic Generation of Synthetic Precipitation Time Series with High Temporal and Spatial.Brommundt@iws.uni-stuttgart.de Introduction The stochastic precipitation time series generator, NiedSim, has been developed and installed been generated. In the year 2004 NiedSim was set up for Hessen and Rheinland-Pfalz. The total project

  20. Bioinspired Fabrication and Characterization of a Synthetic Fish Skin for the Protection of Soft Materials

    E-Print Network [OSTI]

    Barthelat, Francois

    -performance natural armor that represents a source of inspiration for novel engineering designs. In this paper, we consists of a low-modulus elastic mesh or "dermis" layer that holds rigid, plastic scales. The mechanics of the synthetic material is characterized under in-plane, bending, and indentation modes of deformation