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Note: This page contains sample records for the topic "organisms synthetic biology" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
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1

September 16, 2011 Synthetic Biology Leads to Organic Learning  

E-Print Network (OSTI)

principles and mathematical modeling to the design and construction of biological parts, devices, and systems with applications in energy, medicine, and technology. www.bio.davidson -neutral2 1,000,000 gallons in 2008 #12;Synthetic Biology at Davidson College Building Bacterial Computers

Campbell, A. Malcolm

2

Organism, machine, artifact: The conceptual and normative challenges of synthetic biology  

Science Journals Connector (OSTI)

Abstract Synthetic biology is an emerging discipline that aims to apply rational engineering principles in the design and creation of organisms that are exquisitely tailored to human ends. The creation of artificial life raises conceptual, methodological and normative challenges that are ripe for philosophical investigation. This special issue examines the defining concepts and methods of synthetic biology, details the contours of the organism–artifact distinction, situates the products of synthetic biology vis-à-vis this conceptual typology and against historical human manipulation of the living world, and explores the normative implications of these conclusions. In addressing the challenges posed by emerging biotechnologies, new light can be thrown on old problems in the philosophy of biology, such as the nature of the organism, the structure of biological teleology, the utility of engineering metaphors and methods in biological science, and humankind’s relationship to nature.

Sune Holm; Russell Powell

2013-01-01T23:59:59.000Z

3

Designing Synthetic Biology  

Science Journals Connector (OSTI)

(14) The science of biology and the practice of engineering (knowing and making(15)) are especially connected in parts-based synthetic biology, where many engineers and scientists seek to “build life to understand it” through the assembly of standardized genetic modules. ... This iterative refinement of the refactored operon led to a detailed mapping of the genetic design space and an engineered pathway that produced wild-type levels of nitrogen fixation. ... (22) The positive feedback between science and engineering in synthetic biology has been compared to the history of other disciplines and industries, such as aviation(23) or synthetic chemistry. ...

Christina M. Agapakis

2013-10-24T23:59:59.000Z

4

Research Councils UK Synthetic biology  

E-Print Network (OSTI)

, bioinformatics approaches and DNA synthesis, all of which are central to the current field of synthetic biologyResearch Councils UK Synthetic biology #12;Synthetic biology Research funded by the Research them commercially. Synthetic biology is one of `Eight Great Technologies' identified by the Chancellor

Berzins, M.

5

Synthetic biology: Understanding biological design from synthetic circuits  

E-Print Network (OSTI)

An important aim of synthetic biology is to uncover the design principles of natural biological systems through the rational design of gene and protein circuits. Here, we highlight how the process of engineering biological ...

Mukherji, Shankar

6

Synthetic Biology and Metabolic Engineering  

Science Journals Connector (OSTI)

As such, it deals with the engineering (design, construction, and optimization) of native as well as non-natural routes of product synthesis, aided in this task by the availability of synthetic DNA, the core enabling technology of synthetic biology. ... In this context, metabolic engineering is about engineering cell factories for the biological manufacturing of chemical and pharmaceutical products, whereas the main focus of synthetic biology is fundamental biological research facilitated by the use of synthetic DNA and genetic circuits. ... This was soon followed by the emergence of companies offering synthetic DNA as product. ...

Gregory Stephanopoulos

2012-11-01T23:59:59.000Z

7

Synthetic biology: Cultural divide  

Science Journals Connector (OSTI)

... Currently based at the software-design firm Autodesk in San Francisco, California, Hessel represents an increasingly impatient and outspoken faction of synthetic ...

Bryn Nelson

2014-05-07T23:59:59.000Z

8

Synthetic biology and crop engineering  

Energy.gov (U.S. Department of Energy (DOE))

Breakout Session 2: Frontiers and Horizons Session 2-A: Synthetic Biology and the Promise of Biofuels Jonathan Burbaum, Program Director, Department of Energy, Office of Science, ARPA–E

9

Guest Editors' Introduction: Synthetic Biology  

E-Print Network (OSTI)

(microbial production of diesel fuels from fatty acids in Escherichia coli (E. coli) and yeast+ undergraduate participants from around the world. Synthetic Biology had a global market which gene- rated $233, and genetic engineering. The buzz phrasing has not arrived yet. ``Bio Design Automation (BDA)'' or ``Genetic

Densmore, Douglas

10

Synthesizing Law for Synthetic Biology  

E-Print Network (OSTI)

In his Nobel Prize acceptance speech more than half a century ago, Edward L. Tatum suggested an ambitious new goal for biology: "not only to avoid structural and metabolic errors in the developing organism, but also to produce better organisms...

Torrance, Andrew W.

2010-01-01T23:59:59.000Z

11

Synthetic biology: history, challenges and prospects  

Science Journals Connector (OSTI)

...over the last 35 years, the cloning and assembly of synthetic DNA sequences remains a largely bespoke affair. The field...and biological tools for the design and assembly of synthetic DNA-based programmes. Matsuoka et al. (2009) describe...

2009-01-01T23:59:59.000Z

12

Systems Biology 204: Biomolecular Engineering and Synthetic Biology  

E-Print Network (OSTI)

Shih Biomolecular primitives Mon. Sep. 12 Willian Shih DNA origami Wed. Sep. 14 David Zhang SyntheticSystems Biology 204: Biomolecular Engineering and Synthetic Biology SyllabusSynopsis Fall 2011-based synthetic molecular and cellular machinery and systems. Students are mentored to produce substantial term

Bulyk, Martha L.

13

Foundational platform for mammalian synthetic biology  

E-Print Network (OSTI)

The emergent field of synthetic biology is different from many other biological engineering efforts, in that its roots, design principles, and forward engineering perspective have been adopted from electrical engineering ...

Davidsohn, Noah (Noah Justin)

2013-01-01T23:59:59.000Z

14

INTRODUCTION Synthetic biology: history, challenges  

E-Print Network (OSTI)

at a rapid pace over the last 35 years, the cloning and assembly of synthetic DNA sequences remains a largely to establish improved software and bio- logical tools for the design and assembly of synthetic DNA synthetic systems to be described at the level of logical interactions between DNA

Haseloff, Jim

15

Tying new knots in synthetic biology  

SciTech Connect

Recent years have seen the emergence of synthetic biology, which encompasses the engineering of living organisms as well as the implementation of biological behavior in non-living substrates. Many of these engineered systems have harnessed the diverse toolkit of proteins, genes, and cellular processes that nature offers. While these efforts have been fruitful, they have also illustrated the difficulty associated with programming highly complex functions by tapping into cellular processes. Another set of efforts has focused on building circuits, performing computation, and constructing nanoscale machines using nucleic acids. Zhang et al., 2007, Science 318, 1121 1125 and Yin et al., 2008, Nature 451, 318 322 recently demonstrated flexible approaches for the modular construction of such biochemical devices exclusively using DNA. These approaches have exciting implications both for engineering living cells and for mimicking life-like behavior at the nanoscale.

Simpson, Michael L [ORNL; Karig, David K [ORNL

2008-01-01T23:59:59.000Z

16

Abstract The rapidly emerging field of synthetic biology  

E-Print Network (OSTI)

Abstract The rapidly emerging field of synthetic biology originated, as synthetic biology has expanded into mammalian systems, it is increasingly more. Biomaterials will play an important role in advancing synthetic biology

Reisslein, Martin

17

Synthetic Biology Moving into the Clinic  

Science Journals Connector (OSTI)

...secrete key molecules for potential disease treatment, including insulinotropic...murine interleukin-2 in response to xylan . J. Appl. Microbiol. 98 , 1191...of synthetic biology therapies for the treatment of infectious diseases and cancer, as...

Warren C. Ruder; Ting Lu; James J. Collins

2011-09-02T23:59:59.000Z

18

Meta-DNA: synthetic biology via DNA nanostructures and  

E-Print Network (OSTI)

Meta-DNA: synthetic biology via DNA nanostructures and hybridization reactions Harish Chandran1 strands and may be modified to allow for mutations. Keywords: DNA self-assembly; synthetic biology; DNA nanostructures 1. INTRODUCTION 1.1. Synthetic biology using DNA nanosystems A major goal of synthetic biology

Reif, John H.

19

What is Synthetic Biology? Application of engineering principles  

E-Print Network (OSTI)

to the design and construction of biological parts, devices, and systems with applications in energy, medicine;Biofuels from Algae CO -neutral2 1,000,000 gallons in 2008 18 #12;Synthetic Biology Biochemistry

Campbell, A. Malcolm

20

RESEARCH ARTICLE Ensuring the security of synthetic biology--towards  

E-Print Network (OSTI)

RESEARCH ARTICLE Ensuring the security of synthetic biology--towards a 5P governance strategy the label ``synthetic biology'' has been attached to a number of diverse research and commercial activities, ranging from the search for a min- imal cell to the quick delivery of customized genes by DNA synthesis

Sussex, University of

Note: This page contains sample records for the topic "organisms synthetic biology" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


21

Automated Selection of Synthetic Biology Parts for Genetic Regulatory Networks  

E-Print Network (OSTI)

Automated Selection of Synthetic Biology Parts for Genetic Regulatory Networks Fusun Yaman: Raising the level of abstraction for synthetic biology design requires solving several challenging problems, including mapping abstract designs to DNA sequences. In this paper we present the first formalism

Densmore, Douglas

22

Synthetic Biology Domitilla Del Vecchio* and Richard M. Murray**  

E-Print Network (OSTI)

1 Synthetic Biology Domitilla Del Vecchio* and Richard M. Murray** *Department of Mechanical@cds.caltech.edu Abstract--The past decade has seen tremendous advances in DNA recombination and measurement techniques functions is now pos- sible, leading to the birth of a new field called synthetic biology. Sophisticated

Del Vecchio, Domitilla

23

SynFlo: an interactive installation introducing synthetic biology concepts  

Science Journals Connector (OSTI)

SynFlo is an interactive installation that utilizes tangible interaction to help illustrate core concepts of synthetic biology through outreach programs. This playful installation allows users to create useful virtual life forms from standardized genetic ... Keywords: E. chromi, microsoft surface, sifteo cubes, synthetic biology, tangible user interfaces

Kimberly Chang; Wendy Xu; Nicole Francisco; Consuelo Valdes; Robert Kincaid; Orit Shaer

2012-11-01T23:59:59.000Z

24

Meta-DNA: A DNA-Based Approach to Synthetic Biology  

Science Journals Connector (OSTI)

The goal of synthetic biology is to design and assemble synthetic systems that mimic biological systems. One of the most fundamental challenges in synthetic biology is to synthesize artificial biochemical syst...

Harish Chandran; Nikhil Gopalkrishnan…

2014-01-01T23:59:59.000Z

25

Integrating ethical analysis “Into the DNA” of synthetic biology  

Science Journals Connector (OSTI)

How to do this? Such analysis should take account of the fact that synthetic biology has several distinct sub-fields; these... Design of DNA—which can then be placed in a...2010

Patrick Heavey

2014-09-01T23:59:59.000Z

26

Retroactivity, modularity, and insulation in synthetic biology circuits  

E-Print Network (OSTI)

A central concept in synthetic biology is the reuse of well-characterized modules. Modularity simplifies circuit design by allowing for the decomposition of systems into separate modules for individual construction. Complex ...

Lin, Allen

2011-01-01T23:59:59.000Z

27

Defossiling Fuel: How Synthetic Biology Can Transform Biofuel Production  

E-Print Network (OSTI)

Defossiling Fuel: How Synthetic Biology Can Transform Biofuel Production David F. Savage , Jeffrey through natural intermediates to final molecule is long, and biofuel production is perhaps the ultimate engineering, economic, political, and environmental realities. Are biofuels sustainable? Consider U

28

Solitons in synthetic and biological polymers  

SciTech Connect

Solid state and statistical physics applications of soliton mathematics continue to expand rapidly. The present report describes connections between solid state (e.g. synthetic polymer) and biophysics, with strong nonlinearity playing the unifying role. Striking parallels examined include: analytical (as in the case of self-trapping mechanisms); numerical techniques; experimental implications, applications, and techniques. Conventional solid state probes are at last being devoted to biopolymers but their complexity is demanding new extremes and techniques.

Bishop, A.R.

1983-01-01T23:59:59.000Z

29

A synthetic biology approach to bio-chem-ICT: first moves towards chemical communication between synthetic and natural cells  

Science Journals Connector (OSTI)

In this article we present novel aspects of the impact that synthetic biology (SB) can express in a field traditionally based on computer science: information and communication technologies (ICTs), an area that we will consider taking into account also ... Keywords: Artificial intelligence, Autonomy, Autopoiesis, Bio-chem-ICTs, Molecular communication, Quorum sensing, Synthetic biology, Synthetic cells

Giordano Rampioni; Fabio Mavelli; Luisa Damiano; Francesca D'angelo; Marco Messina; Livia Leoni; Pasquale Stano

2014-09-01T23:59:59.000Z

30

IT for synthetic biology and DNA nanotechnology  

Science Journals Connector (OSTI)

Somewhere between the studies of information technology and organic chemistry, researchers are trying to make tiny robots out of DNA molecules.

Masami Hagiya; Fumiaki Tanaka; Ibuki Kawamata

2010-09-01T23:59:59.000Z

31

NATURE BIOTECHNOLOGY VOLUME 24 NUMBER 5 MAY 2006 545 RNA synthetic biology  

E-Print Network (OSTI)

synthetic biology efforts have focused on engineering gene cir- cuits that rely on protein-DNA interactionsNATURE BIOTECHNOLOGY VOLUME 24 NUMBER 5 MAY 2006 545 RNA synthetic biology Farren J Isaacs1, Daniel two years efforts in synthetic biology have produced novel, synthetic RNA components capable

Collins, James J.

32

Renewable Energy from Synthetic Biology (LBNL Science at the Theater)  

ScienceCinema (OSTI)

Jay Keasling, co-leader of Berkeley Lab's Helios Project, is a groundbreaking researcher in the new scientific field of synthetic biology. In Helios, he directs the biology program, incorporating a range of approaches to increasing the efficacy and economy of plants and cellulose-degrading microbes to make solar-based fuels. He is a UC Berkeley professor of Chemical and Bioengineering, and founder of Amyris Biotechnologies, a company that was honored as a Technology Pioneer for 2006 by the World Economic Forum. Keasling has succeeded in using synthetic biology to develop a yeast-based production scheme for precursors of the antimalarial drug artemisinin in work funded by the Bill & Melinda Gates Foundation.

Keasling, Jay

2011-04-28T23:59:59.000Z

33

Meta-DNA: Synthetic Biology via DNA Nanostructures and Hybridization Reactions  

E-Print Network (OSTI)

Meta-DNA: Synthetic Biology via DNA Nanostructures and Hybridization Reactions Harish Chandran University, Durham NC email: reif@cs.duke.edu Abstract The goal of synthetic biology is to design and assemble synthetic systems that mimic bio- logical systems. One of the most fundamental challenge

Reif, John H.

34

A Method for Fast, High-Precision Characterization of Synthetic Biology Devices  

E-Print Network (OSTI)

Engineering biological systems with predictable behavior is a foundational goal of synthetic biology. To accomplish this, it is important to accurately characterize the behavior of biological devices. Prior characterization ...

Beal, Jacob

2012-04-07T23:59:59.000Z

35

A machine that speeds up evolution is revolutionizing genome design A new tool for synthetic biology  

E-Print Network (OSTI)

Engineering (MAGE) The Principle of Accelerated Evolution · Synthetic DNA is repeatedy A new tool for synthetic biology We are in the midst of a genomic ("write") the DNA that makes up genomic information. However, current

Wood, Robert

36

Flourishing and Discordance: On Two Modes of Human Science Engagement with Synthetic Biology  

E-Print Network (OSTI)

single stranded synthetic DNA, the fact that ligation indo: putting a piece of synthetic DNA in a host. But I thinksynthetic biology was intensifying already-known challenges in recombinant DNA

Stavrianakis, Anthony

2012-01-01T23:59:59.000Z

37

Single Molecule and Synthetic Biology Studies of Transcription  

E-Print Network (OSTI)

GenScript returned the synthetic DNA cloned into the EcoRIis pre-formed using synthetic DNA and RNA oligonucleotides.synthetic oligonucleotides, including those used as PCR primers, were synthesized by Integrated DNA

Zamft, Bradley Michael

2011-01-01T23:59:59.000Z

38

Uncertainty in synthetic biology for release and possibilities for regulation under the Toxic Substances Control Act  

E-Print Network (OSTI)

The emerging field of synthetic biology is developing rapidly and promises diverse applications. Many anticipated applications, particularly those involving release of engineered microbes into the environment or human ...

Lightfoot, Shlomiya

2014-01-01T23:59:59.000Z

39

Single Molecule and Synthetic Biology Studies of Transcription  

E-Print Network (OSTI)

GenScript returned the synthetic DNA cloned into the EcoRIis pre-formed using synthetic DNA and RNA oligonucleotides.

Zamft, Bradley Michael

2011-01-01T23:59:59.000Z

40

Meta-DNA: synthetic biology via DNA nanostructures and hybridization reactions  

Science Journals Connector (OSTI)

...articles 1004 181 131 18 Meta-DNA: synthetic biology via DNA nanostructures...protocols for its manipulation. Synthetic DNA is also cheaply and readily available...specific to mDNA and also occurs in synthetic DNA synthesis. One of the key technological...

2012-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "organisms synthetic biology" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


41

Synthetic Biology Slides by Daisuke KigaSlides by Daisuke Kiga  

E-Print Network (OSTI)

#12; DNA RNA #12;Synthetic Biology Slides by Daisuke KigaSlides by Daisuke Kiga #12;Two #12; DNA RNA DNA DNA #12; DNA RNA DNA DNA #12; DNA RNA DNA DNA translation DNAamino acid translation signal transduction rhythm RNA protein nucleotide Synthetic Biology #12

Hagiya, Masami

42

Biological Hydrogen Production Using Synthetic Wastewater Biotin and glutamic acid are not required for biological hydrogen production.  

E-Print Network (OSTI)

Biological Hydrogen Production Using Synthetic Wastewater Conclusion ·Biotin and glutamic acid are not required for biological hydrogen production. ·MgSO4 .7H2O is a required nutrient, but hydrogen production work should focus on minimizing the lag time in biological hydrogen production, by varying nutrient

Barthelat, Francois

43

R2oDNA Designer: Computational Design of Biologically Neutral Synthetic DNA Sequences  

Science Journals Connector (OSTI)

R2oDNA Designer: Computational Design of Biologically Neutral Synthetic DNA Sequences ... As the cost of whole gene synthesis is decreasing, whole genome synthesis at the other end of the spectrum has expanded our horizons to the prospect of fully engineered synthetic cells. ...

Arturo Casini; Georgia Christodoulou; Paul S. Freemont; Geoff S. Baldwin; Tom Ellis; James T. MacDonald

2014-01-31T23:59:59.000Z

44

Bringing Standards to Life: Synthetic Biology Standards and Intellectual Property  

E-Print Network (OSTI)

& KAHL 4/2/2014 11:00 PM 2014] BRINGING STANDARDS TO LIFE 213 Standard Biological Parts.84 Similarly, the Joint BioEnergy Institute Inventory of Composable Elements (JBEI-ICE), a public registry of biological parts developed by the Joint BioEnergy...

Torrance, Andrew W.; Kahl, Linda

2014-01-01T23:59:59.000Z

45

Harnessing nature's toolbox: regulatory elements for synthetic biology  

Science Journals Connector (OSTI)

...biological chassis are an ideal platform for chemical production. It has been noted...Gibson, D. G. , 2008 Complete chemical synthesis, assembly, and cloning...rational design of microbial chemical factories. Curr. Opin. Biotechnol...

2009-01-01T23:59:59.000Z

46

Synthetic biology and biomass conversion: a match made in heaven?  

Science Journals Connector (OSTI)

...Y. 2007 Harnessing energy from plant biomass. Curr. Opin. Chem...processes for conversion of biomass to useful products...Biodegradation, Environmental Biomass Biotechnology methods...Biology methods Ecology Energy-Generating Resources...

2009-01-01T23:59:59.000Z

47

Engineering the interface between cellular chassis and synthetic biological systems  

E-Print Network (OSTI)

The aim of my thesis is to help enable the engineering of biological systems that behave in a predictable manner. Well-established techniques exist to engineer systems that behave as expected. Here, I apply such techniques ...

Canton, Bartholomew (Bartholomew John)

2008-01-01T23:59:59.000Z

48

Stabilizing synthetic data in the DNA of living organisms  

Science Journals Connector (OSTI)

Data-encoding synthetic DNA, inserted into the genome of a living ... generations, one of the merits of using DNA material is long-term data storage within ... broken by mutation, deletion, and insertion of DNA, ...

Nozomu Yachie; Yoshiaki Ohashi; Masaru Tomita

2008-06-01T23:59:59.000Z

49

Free Synthetic Biology Workshop June 24-27, 2014  

E-Print Network (OSTI)

? Implementation of engineering principles and mathematical modeling to the design and construction of biological parts, devices, and systems with applications in energy, medicine, and technology. www.bio.davidson from Algae CO -neutral2 1,000,000 gallons in 2008 Monday, November 18, 2013 #12;Intro Bio Students

Campbell, A. Malcolm

50

The modeling and the simulation of the fluid machines of synthetic biology  

Science Journals Connector (OSTI)

In the past century, several conceptual and technological breakthroughs produced the digital computers and open the digital information age. At the very same time, the Watson --- Crick model of the digital coding of the genetic information was developed. ... Keywords: (DS)2: dynamical systems with a dynamical structure, MGS, computer modeling, domain specific language (DSL), fluid machines, simulation, spatial computing, synthetic biology, topological rewriting

Jean-Louis Giavitto

2011-08-01T23:59:59.000Z

51

Engineering scalable biological systems  

E-Print Network (OSTI)

Synthetic biology is focused on engineering biological organisms to study natural systems and to provide new solutions for pressing medical, industrial, and environmental problems. At the core of engineered organisms are ...

Lu, Timothy K.

52

Assembly of Designed Oligonucleotides: A Useful Tool in Synthetic Biology for Creating High-Quality Combinatorial DNA Libraries  

Science Journals Connector (OSTI)

The method dubbed Assembly of Designed Oligonucleotides (ADO) is a powerful tool in synthetic biology to create combinatorial DNA libraries for gene, protein, metabolic, and ... amino acid alphabets for saturatio...

Carlos G. Acevedo-Rocha; Manfred T. Reetz

2014-01-01T23:59:59.000Z

53

miniEugene: A Web-based Software Tool for Constraint-based Design Specifications of Synthetic Biological Systems  

Science Journals Connector (OSTI)

miniEugene: A Web-based Software Tool for Constraint-based Design Specifications of Synthetic Biological Systems ... Publication Date (Web): November 26, 2014 ... We also provide links and references to more information on the miniEugene web application and the integration of the miniEugene software library into sophisticated Computer-Aided Design (CAD) tools for synthetic biology (www.eugenecad.org). ...

Ernst Oberortner; Douglas Densmore

2014-11-26T23:59:59.000Z

54

A syntactic model to design and verify synthetic genetic constructs derived from standard biological parts  

Science Journals Connector (OSTI)

......parsers capable of verifying the structural validity of a synthetic DNA sequence. Several prominent synthetic biologists have...2006), a software application to quickly design synthetic DNA molecules from a library of basic parts, has been inspired......

Yizhi Cai; Brian Hartnett; Claes Gustafsson; Jean Peccoud

2007-10-15T23:59:59.000Z

55

Flourishing and Discordance: On Two Modes of Human Science Engagement with Synthetic Biology  

E-Print Network (OSTI)

single stranded synthetic DNA, the fact that ligation indo: putting a piece of synthetic DNA in a host. But I think

Stavrianakis, Anthony

2012-01-01T23:59:59.000Z

56

Self-organizing molecular photonic structures based on functionalized synthetic nucleic acid (DNA) polymers  

Science Journals Connector (OSTI)

Work has been carried out with the objective of imparting the electronic/photonic property of extended Forster energy transfer into organized structures formed by the programmed self-assembly of synthetic nucleic acid units (fluorescent oligonucleotides and polynucleotides). Forster energy transfer is a non-radiative process by which a fluorescent donor molecule excited at one wavelength is able to transfer its absorbed photonic energy efficiently to a fluorescent acceptor molecule, in close proximity, which then re-emits it at a second wavelength. An extended energy transfer system, with multiple donor molecules, could be considered a molecular photonic antenna or amplifier structure. Relatively efficient extended Forster energy transfer was observed in initial experiments involving multiple fluorescent donor and acceptor oligonucleotides. These results provide a clear demonstration of totally synthetic molecules, with highly specific programmable self-assembling properties, organizing into molecular structures with useful electronic/photonic properties.

M J Heller; R H Tullis

1991-01-01T23:59:59.000Z

57

Combined X-ray and neutron fibre diffraction studies of biological and synthetic polymers.  

SciTech Connect

The fibrous state is a natural one for polymer molecules which tend to assume regular helical conformations rather than the globular structures characteristic of many proteins. Fibre diffraction therefore has broad application to the study of a wide range of biological and synthetic polymers. The purpose of this paper is to illustrate the general scope of the method and in particular to demonstrate the impact of a combined approach involving both X-ray and neutron diffraction methods. While the flux of modern X-ray synchrotron radiation sources allows high quality datasets to be recorded with good resolution within a very short space of time, neutron studies can provide unique information through the ability to locate hydrogen or deuterium atoms that are often difficult or impossible to locate using X-ray methods. Furthermore, neutron fibre diffraction methods can, through the ability to selectively label specific parts of a structure, be used to highlight novel aspects of polymer structure that can not be studied using X-rays. Two examples are given. The first describes X-ray and neutron diffraction studies of conformational transitions in DNA. The second describes structural studies of the synthetic high-performance polymer poly(p-phenylene terephthalamide) (PPTA), known commercially as Kevlar{reg_sign} or Twaron{reg_sign}.

Parrot, I. M. [Institut Laue-Langevin (ILL); Urban, Volker S [ORNL; Gardner, K. H. [DuPont Experimental Station; Forsyth, V. T. [Institut Laue Langevin and Keele University

2005-04-01T23:59:59.000Z

58

Voyage of RepA protein from plasmid DNA replication through amyloid aggregation towards synthetic biology  

Science Journals Connector (OSTI)

Summary DNA replication of plasmids in Gram-negative bacteria has been an object of study at CIB-CSIC for nearly 30 years. We have been focused on the enterobacterial antibiotic resistance factor R1 (1981–1992) and the pPS10 replicon from the phytopathogen Pseudomonas savastanoi (since 1984). Our group has used multidisciplinary (genetic, biochemical and biophysical-structural) approaches to unravel the molecular mechanism for the activation of RepA. Rep-type plasmidic proteins are either transcriptional repressors or replication initiators/inhibitors, depending on their association state (dimers vs. monomers) and targeting of alternative (operator or iteron) DNA sites. We discovered that allosteric DNA-binding remodels the structure of RepA N-terminal domain (WH1), transforming ?-helical portions into ?-strands. This precisely tunes the distances between the DNA reading heads in WH1 and the C-terminal domain (WH2), to match the target operator or iteron sequences. We have recently moved into engineering such structural transformation in RepA-WH1 to build-up synthetic protein devices that allow for customized ligand (DNA)-promoted amyloidogenesis. Our basic studies on plasmid DNA replication are relevant for settling the bases of a minimalist bacterial model to tackle transmissible amyloid proteinopathies and are a valuable tool for bottom-up synthetic biology.

Rafael Giraldo; María Elena Fernández-Tresguerres

2010-01-01T23:59:59.000Z

59

Green Algae as Model Organisms for Biological Fluid Dynamics  

E-Print Network (OSTI)

In the past decade the volvocine green algae, spanning from the unicellular $Chlamydomonas$ to multicellular $Volvox$, have emerged as model organisms for a number of problems in biological fluid dynamics. These include flagellar propulsion, nutrient uptake by swimming organisms, hydrodynamic interactions mediated by walls, collective dynamics and transport within suspensions of microswimmers, the mechanism of phototaxis, and the stochastic dynamics of flagellar synchronization. Green algae are well suited to the study of such problems because of their range of sizes (from 10 $\\mu$m to several millimetres), their geometric regularity, the ease with which they can be cultured and the availability of many mutants that allow for connections between molecular details and organism-level behavior. This review summarizes these recent developments and highlights promising future directions in the study of biological fluid dynamics, especially in the context of evolutionary biology, that can take advantage of these remarkable organisms.

Raymond E. Goldstein

2014-09-08T23:59:59.000Z

60

Chapter Ten - DNA Assembler: A Synthetic Biology Tool for Characterizing and Engineering Natural Product Gene Clusters  

Science Journals Connector (OSTI)

Abstract The majority of existing antibacterial and anticancer drugs are natural products or their derivatives. However, the characterization and engineering of these compounds are often hampered by limited ability to manipulate the corresponding biosynthetic pathways. Recently, we developed a genomics-driven, synthetic biology-based method, DNA assembler, for discovery, characterization, and engineering of natural product biosynthetic pathways (Shao, Luo, & Zhao, 2011). By taking advantage of the highly efficient yeast in vivo homologous recombination mechanism, this method synthesizes the entire expression vector containing the target biosynthetic pathway and the genetic elements needed for DNA maintenance and replication in individual hosts in a single-step manner. In this chapter, we describe the general guidelines for construct design. By using two distinct biosynthetic pathways, we demonstrate that DNA assembler can perform multiple tasks, including heterologous expression, introduction of single or multiple point mutations, scar-less gene deletion, generation of product derivatives, and creation of artificial gene clusters. As such, this method offers unprecedented flexibility and versatility in pathway manipulations.

Zengyi Shao; Huimin Zhao

2012-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "organisms synthetic biology" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


61

Green Algae as Model Organisms for Biological Fluid Dynamics  

E-Print Network (OSTI)

In the past decade the volvocine green algae, spanning from the unicellular $Chlamydomonas$ to multicellular $Volvox$, have emerged as model organisms for a number of problems in biological fluid dynamics. These include flagellar propulsion, nutrient uptake by swimming organisms, hydrodynamic interactions mediated by walls, collective dynamics and transport within suspensions of microswimmers, the mechanism of phototaxis, and the stochastic dynamics of flagellar synchronization. Green algae are well suited to the study of such problems because of their range of sizes (from 10 $\\mu$m to several millimetres), their geometric regularity, the ease with which they can be cultured and the availability of many mutants that allow for connections between molecular details and organism-level behavior. This review summarizes these recent developments and highlights promising future directions in the study of biological fluid dynamics, especially in the context of evolutionary biology, that can take advantage of these re...

Goldstein, Raymond E

2014-01-01T23:59:59.000Z

62

C H A P T E R F O U R T E E N Microfluidics for Synthetic Biology  

E-Print Network (OSTI)

C H A P T E R F O U R T E E N Microfluidics for Synthetic Biology: From Design to Execution M. S of a microfluidic chip 298 1.2. A parallel DAW device 322 1.3. Cell tracking 326 1.4. DAW hardware and software 334. coli 358 3.2. Method to set up a MDAW microfluidic experiment 364 Acknowledgments 371 References 371

Hasty, Jeff

63

Gene Designer: a synthetic biology tool for constructing artificial DNA segments  

Science Journals Connector (OSTI)

Gene Designer is a stand-alone software for fast and easy design of synthetic DNA segments. Users can easily add, edit ... drag-and-drop graphic interface and a hierarchical DNA/Protein object map. Using advanced...

Alan Villalobos; Jon E Ness; Claes Gustafsson; Jeremy Minshull…

2006-06-01T23:59:59.000Z

64

Handbook of Synthetic Photochemistry  

Science Journals Connector (OSTI)

Handbook of Synthetic Photochemistry ... Comprehensive overviews of synthetically relevant photochemical processes have appeared previously, most recently in Synthetic Organic Photochemistry, edited by Griesbeck and Mattay (2005), and in the CRC Handbook of Organic Photochemistry and Photobiology, edited by Horspool and Lenci (2004). ... Handbook of Synthetic Photochemistry . ...

Frederick G. West

2010-10-11T23:59:59.000Z

65

Scalable Genetic System Design Using Synthetic RNA Regulators  

E-Print Network (OSTI)

longest length of synthetic DNA increases exponentially (DNA sequencing, DNA synthesis, and synthetic biology……. …3of DNA sequencing, DNA synthesis, and synthetic biology. (A)

Qi, Lei

2012-01-01T23:59:59.000Z

66

Co-culture systems and technologies: taking synthetic biology to the next level  

Science Journals Connector (OSTI)

...1. Extracellular environment: a tunable dial The...and synthetic, or to engineer new such interactions...by the extracellular environment, which in turn is...analogy. Just as civil engineers need to consider the...consider the working environment of bio-parts at the...

2014-01-01T23:59:59.000Z

67

Theory: Biological systems organize to maximize entropy production subject to information and biophysicochemical constraints.  

E-Print Network (OSTI)

Theory: Biological systems organize to maximize entropy production subject to information production. While organized structures decrease the entropy of the system, they are maintained by external selection produce biological systems that tend to follow a pathway of maximum entropy production

Vallino, Joseph J.

68

RIKEN Center for Life Science Technologies Division of Structural and Synthetic Biology  

E-Print Network (OSTI)

Structural Biology Platform Unit Drug Discovery Computational Chemistry Platform Unit Division of Genomic Division of Bio-Function Dynamics Imaging Imaging Chemistry Group Labelling Chemistry Team Chemical Biology Chemistry Platform Unit Drug Discovery Imaging Platform Unit Center Director's Strategic Program Life

Fukai, Tomoki

69

Self-assembly of synthetic and biological components in water using cucurbit[8]uril  

E-Print Network (OSTI)

. Current technology can successfully build assemblies from the bottom up, assembling complex architectures using such building blocks as DNA,14,24–26 peptides,27,28 saccharides,29,30 lipids,31–33 as well as synthetic polymer com- ponents.34–37 1900 1950... nature of an aqueous envir- onment are still being explored, and some notable examples are provided in Fig. 1.3. 3 Chapter 1 Introduction It is worthy of note that in each case, multiple non-covalent interactions work in concert, as is the case in nature...

Zayed, Jameel Majed

2012-02-07T23:59:59.000Z

70

Synthetic and organic fungicide control of apple scab: 2009 field trial  

E-Print Network (OSTI)

during leaf fall to control apple scab (Venturia inaequalis)mixtures on scab control in apple orchards. Plant Pathologyscab development in an organic apple orchard. Agriculture,

Janousek, Christopher N; Bay, Ian S; Gubler, W. Douglas

2009-01-01T23:59:59.000Z

71

Synthetic DNA and Biology  

Science Journals Connector (OSTI)

“Most of the significant work has been summarized in a number of reviews and articles. In these there was, of necessity, a good deal of simplification and omission of detail .... With the passage of time, even...

Michael Smith

1994-04-01T23:59:59.000Z

72

Reverse osmosis for removing synthetic organics from drinking water: a cost and performance evaluation  

SciTech Connect

Reverse osmosis for removing organic compounds from drinking water has considerable promise. Bench and pilot plant studies on actual waters have shown that several organics proposed for regulation can be removed by reverse osmosis. As membrane technology improves, rejection of more difficult to remove compounds is expected to improve. Also, smaller volumes of concentrate are expected to be produced that can be handled more cost-effectively. One major concern with the use of reverse osmosis is concentrate disposal, which may increase the overall cost of treatment and disposal. The cost of reverse osmosis is very sensitive to such factors as recovery, economies of scale, systems configuration, membrane type, and electric power cost. In certain situations, reverse osmosis is a viable treatment option that is not cost-prohibitive.

Lykins, B.W.; Clark, R.M.; Fronk, C.A.

1988-06-01T23:59:59.000Z

73

Photoconversion of gasified organic materials into biologically-degradable plastics  

DOE Patents (OSTI)

A process is described for converting organic materials (such as biomass wastes) into a bioplastic suitable for use as a biodegradable plastic. In a preferred embodiment the process involves thermally gasifying the organic material into primarily carbon monoxide and hydrogen, followed by photosynthetic bacterial assimilation of the gases into cell material. The process is ideally suited for waste recycling and for production of useful biodegradable plastic polymer. 3 figures.

Weaver, P.F.; Pinching Maness.

1993-10-05T23:59:59.000Z

74

Photoconversion of gasified organic materials into biologically-degradable plastics  

DOE Patents (OSTI)

A process is described for converting organic materials (such as biomass wastes) into a bioplastic suitable for use as a biodegradable plastic. In a preferred embodiment the process involves thermally gasifying the organic material into primarily carbon monoxide and hydrogen, followed by photosynthetic bacterial assimilation of the gases into cell material. The process is ideally suited for waste recycling and for production of useful biodegradable plastic polymer.

Weaver, Paul F. (Golden, CO); Maness, Pin-Ching (Golden, CO)

1993-01-01T23:59:59.000Z

75

The proper place of hopeful monsters in evolutionary biology  

Science Journals Connector (OSTI)

Hopeful monsters are organisms with a profound mutant phenotype that have the potential to establish a new evolutionary lineage. The Synthetic Theory of evolutionary biology has rejected the evolutionary relev...

Günter Theißen

2006-03-01T23:59:59.000Z

76

Collaboration, Stars, and the Changing Organization of Science: Evidence from Evolutionary Biology  

E-Print Network (OSTI)

Collaboration, Stars, and the Changing Organization of Science: Evidence from Evolutionary Biology to changing patterns of collaboration, perhaps caused by the rising burden of knowledge and the falling cost of communication, both of which increase the returns to collaboration. Indeed, we report evidence

Sekhon, Jasjeet S.

77

Evolution and Biodiversity All of biology rests on the fundamental principle that organisms, and their characteristics, are the  

E-Print Network (OSTI)

1 Evolution and Biodiversity All of biology rests on the fundamental principle that organisms and Biodiversity Option will enable students to pursue jobs in a diversity of biological fields. Many students, Phylogenetics, and Biodiversity group familiarizes students with organisms in an evolutionary context, while

Wurtele, Eve Syrkin

78

Metal?organic frameworks for the storage and delivery of biologically active hydrogen sulfide  

SciTech Connect

Hydrogen sulfide is an extremely toxic gas that is also of great interest for biological applications when delivered in the correct amount and at the desired rate. Here we show that the highly porous metal-organic frameworks with the CPO-27 structure can bind the hydrogen sulfide relatively strongly, allowing the storage of the gas for at least several months. Delivered gas is biologically active in preliminary vasodilation studies of porcine arteries, and the structure of the hydrogen sulfide molecules inside the framework has been elucidated using a combination of powder X-ray diffraction and pair distribution function analysis.

Allan, Phoebe K.; Wheatley, Paul S.; Aldous, David; Mohideen, M. Infas; Tang, Chiu; Hriljac, Joseph A.; Megson, Ian L.; Chapman, Karena W.; De Weireld, Guy; Vaesen, Sebastian; Morris, Russell E. (St Andrews)

2012-04-02T23:59:59.000Z

79

Synthetic Design of New Metal-Organic Framework Materials for Hydrogen Storage - DOE Hydrogen and Fuel Cells Program FY 2012 Annual Progress Report  

NLE Websites -- All DOE Office Websites (Extended Search)

9 9 FY 2012 Annual Progress Report DOE Hydrogen and Fuel Cells Program Pingyun Feng (Primary Contact), Qipu Lin, Xiang Zhao Department of Chemistry University of California Riverside, CA 92521 Phone: (951) 827-2042 Email: pingyun.feng@ucr.edu DOE Program Officer: Dr. Michael Sennett Phone: (301) 903-6051 Email: Michael.Sennett@science.doe.gov Objectives Design and * synthesize new metal-organic framework materials using lightweight chemical elements to help improve gravimetric hydrogen storage capacity. Develop new synthetic strategies to generate novel * active binding sites on metal ions and ligands to enhance solid-gas interactions for increased uptake near ambient conditions.

80

Consumer Choice and Dempster-Shafer Models of Threat Prioritization for Emerging Dual-Use Technologies: Their Application to Synthetic Biology  

SciTech Connect

Identification and prioritization of risks to international security associated with emerging dual-use technologies presents numerous challenges. First, it demands prediction of the evolving states-of-the-art in various technological fields and, second, it requires a comprehension of the motivations and prospective selection criteria that illicit users might adopt in choosing among new technologies and their means of deployment. Nevertheless, the identification and prioritization of such threats is critical in establishing the appropriate focal points for proactive, nonproliferation policy-making. This paper addresses the question of how the threats associated with alternative means of deploying an emerging technology might be prioritized. The method revolves around systematic identification of the technological barriers to an illicit user in deploying a new technology. Evaluation of the resources necessary to overcome the barriers - such acquisition of the necessary intellectual capital and laboratory assets - then provides the basis for assessing the relative likelihoods or plausibilities of various deployment scenarios. Two optional bases are outlined for quantification of the model. One is a choice model that has found application in the analysis of consumer behavior, where the illicit user is modeled essentially as a consumer of new technology. The other employs a Dempster-Shafer framework for priority characterization. The paper describes application of the methodology to emerging life science technologies; in particular, to synthetic biology - the means of engineering biological systems. The prospect of a terrorist being able to synthesize natural pathogens or, perhaps worse still, to engineer pathogens not present in nature, creates an unprecedented threat to international security. Use of the proposed methodology to identify and prioritize threats associated with the engineering of pathogens is described.

Unwin, Stephen D.; Fecht, Barbara A.

2009-03-01T23:59:59.000Z

Note: This page contains sample records for the topic "organisms synthetic biology" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


81

Synthetic Rubber  

Science Journals Connector (OSTI)

... acutely sensitive, justifiably, about synthetic rubber. His review of my book in NATURE of December 26, p. 751, is unfair in several respects. Undoubtedly, there are errors in ...

HARRY BARRON

1943-02-06T23:59:59.000Z

82

Advanced Review Synthetic biology: putting  

E-Print Network (OSTI)

technologies that serve to address important and current problems in environment, energy, and health. However@illinois.edu 1 Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, USA 2Department of Chemistry, University of Illinois at Urbana- Champaign, Urbana, IL, USA 3

Zhao, Huimin

83

Synthetic biology?putting engineering into biology  

Science Journals Connector (OSTI)

......well-known E.coli regulatory circuits, first steps...implementation of suitable regulatory circuitry and the possibility...transformation of design plans into actual physical...referred to a recent review (Schueler-Furman...Design of signaling and regulatory networks Artificial......

Matthias Heinemann; Sven Panke

2006-11-15T23:59:59.000Z

84

Synthetic biology?putting engineering into biology  

Science Journals Connector (OSTI)

......analogies to elements from electric circuits such as switches...two of the Tn10 tetracycline resistance operon, makes the P L promoter...Varma and Palsson, 1994) and elementary flux mode (Schuster et al...et al. 1999Detection of elementary flux modes in biochemical......

Matthias Heinemann; Sven Panke

2006-11-15T23:59:59.000Z

85

Cellular delivery and site-specific targeting of organic fluorophores for super-resolution imaging in living cells  

E-Print Network (OSTI)

Recent advances in super-resolution fluorescence microscopy have pushed the spatial resolution of biological imaging down to a few nanometers. The key element to the development of such imaging modality is synthetic organic ...

Uttamapinant, Chayasith

2013-01-01T23:59:59.000Z

86

Meta-DNA: A DNA-Based Approach to Synthetic Harish Chandran1  

E-Print Network (OSTI)

Meta-DNA: A DNA-Based Approach to Synthetic Biology Harish Chandran1 harish@cs.duke.edu Nikhil Gopalkrishnan, Bernard Yurke, John Reif, Meta-DNA: Synthetic Biology via DNA Nanostructures and Hybridization@cs.duke.edu Abstract The goal of synthetic biology is to design and assemble synthetic systems that mimic bio- logical

Reif, John H.

87

Conservation biology: The new consensus When conservation biology emerged as an identifiable organized discipline in the late 1980s [for  

E-Print Network (OSTI)

in which the conservation of biodiversity was seen as part of the biocultural restoration of degraded in promoting the idea that much can be learnt about biodiversity conservation from traditional ecologicali Preface Conservation biology: The new consensus When conservation biology emerged

Sarkar, Sahotra

88

Synthetic gene oscillators and their applications  

E-Print Network (OSTI)

of 25 overlapping DNA fragments to form a complete syntheticof synthetic organisms, and ”bottom- up” DNA construction ofsynthetic biologists’ attempts to design life by constructing DNA

Danino, Tal

2011-01-01T23:59:59.000Z

89

Single cell growth and gene expression dynamics in model organisms  

E-Print Network (OSTI)

is used to construct synthetic DNA constructs and integrateof synthetic biology. First is the ability to cleave DNA,Synthetic Biology in Practice Molecular Biology The increasing ease with which scientists are able to modify DNA

Cookson, Natalie Anne

2009-01-01T23:59:59.000Z

90

Consistent design schematics for biological systems: standardization of representation in biological engineering  

Science Journals Connector (OSTI)

...for understanding as well as engineering biological systems. At the...synthetic biology matures as an engineering field, the issues discussed...can be regarded as precision engineering. One contribution to a Theme Supplement Synthetic biology: history, challenges and prospects...

2009-01-01T23:59:59.000Z

91

Superposition and Synthetic Genetic Devices: Framework and Model System to Investigate Linearity in Escherichia coli  

E-Print Network (OSTI)

into the host cell as DNA, a synthetic device must first beAdie T, Baldwin GS: DNA assembly for synthetic biology: fromdevices (synthetic and native) in the form of DNA act as

Hajimorad, Meghdad

2011-01-01T23:59:59.000Z

92

future science group 9ISSN 1759-726910.4155/BFS.11.151 2012 Future Science Ltd Synthetic biology approaches to biofuel production  

E-Print Network (OSTI)

approaches to biofuel production Editorial Biofuels (2012) 3(1), 9­12 "...it is important for synthetic there is a tendency, par- ticularly in the algae biofuel space, to prioritize high yields without sufficient regard large enough volumes of biofuels at a low enough cost to make this significant leap in the national

Hasty, Jeff

93

Analysis and removal of assimilable organic carbon (AOC) from treated drinking water using a biological activated carbon filter system  

Science Journals Connector (OSTI)

Abstract This study is focused on reducing the concentration of assimilable organic carbon (AOC) in treated drinking water. Experiments were conducted to evaluate the efficiency of AOC removal by biological activated carbon filters (BACF) in a pilot-scale system. The results show that BACF reduces the total concentration of AOC. The concentration of AOC primarily indicates microorganism growth in a water supply network, and the amount of AOC in water is significantly reduced after BACF treatment. The predicted and measured values of AOC in output water treated by the BACF system show linear relationships, and their correlation coefficients are high. An AOC empirical equation was established by determining the relationship between water quality parameters such as total organic carbon, dissolved organic carbon, UV254, ammonia nitrogen, and total phosphorous. These findings may be relevant to conventional water treatment plants or to water distribution systems to provide treated drinking water with a high level of biological stability.

Jie-Chung Lou; Chih-Yuan Yang; Che-Jung Chang; Wei-Hsiang Chen; Wei-Bin Tseng; Jia-Yun Han

2014-01-01T23:59:59.000Z

94

Self–organized living systems: conjunction of a stable organization with chaotic fluctuations in biological space–time  

Science Journals Connector (OSTI)

...helix (Watson 1968), that he went to the library and he had to read less than 10 papers on...conjecture is that living systems operate in a space with a changing num- ber of dimensions (biological space-time), and that it is this very ability...

2003-01-01T23:59:59.000Z

95

Structurally Integrated Photoluminescent Chemical and Biological Sensors: An Organic Light-Emitting Diode-Based Platform  

Science Journals Connector (OSTI)

The chapter describes the development, advantages, challenges, and potential of an emerging, compact photoluminescence-based sensing platform for chemical and biological analytes, including multiple analytes. In ...

J. Shinar; R. Shinar

2008-01-01T23:59:59.000Z

96

Biological removal of organic constituents in quench waters from high-Btu coal-gasification pilot plants  

SciTech Connect

Studies were initiated to assess the efficiency of bench-scale, activated-sludge treatment for removal of organic constituents from coal-gasification process effluents. Samples of pilot-plant, raw-gas quench waters were obtained from the HYGAS process of the Institute of Gas Technology and from the slagging, fixed-bed (SFB) process of the Grand Forks Energy Technology Center. The types of coal employed were Bituminous Illinois No. 6 for the HYGAS and Indian Head lignite for the SFB process. These pilot-plant quench waters, while not strictly representative of commercial condensates, were considered useful to evaluate the efficiency of biological oxidation for the removal of organics. Biological-reactor influent and effluent samples were extracted using a methylene chloride pH-fractionation method into acid, base, and neutral fractions, which were analyzed by capillary-column gas-chromatography/mass-spectrometry. Influent acid fractions of both HYGAS and SFB condensates showed that nearly 99% of extractable and chromatographable organic material comprised phenol and alkylated phenols. Activated-sludge treatment removed these compounds almost completely. Removal efficiency of base-fraction organics was generally good, except for certain alkylated pyridines. Removal of neutral-fraction organics was also good, except for certain alkylated benzenes, certain polycyclic aromatic hydrocarbons, and certain cycloalkanes and cycloalkenes, especially at low influent concentrations.

Stamoudis, V C; Luthy, R G

1980-02-01T23:59:59.000Z

97

Systems Biology at Harvard Medical School The Department of Systems Biology was founded in 2003 in response to a growing  

E-Print Network (OSTI)

, engineering improved carbon fixation and making useful molecules such as hydrogen, sugar, and other products for the very best young researchers in this area, and the related field of synthetic biology. The department-enabled methods for measuring cell growth, aging, gene expression, and cell movement in model organisms; o A new

Needleman, Daniel

98

Organic Matter Composition, Recycling Susceptibility, and the Effectiveness of the Biological Pump – An Evaluation Using NMR Spectra of Marine Plankton  

SciTech Connect

Carbon (C) sequestration through fertilization of phytoplankton with micronutrients and enhancement of the absorption and retention of atmospheric C by ocean biota heavily depends on the efficiency of the “biological pump”. The long-term effectiveness of this strategy depends on a net transfer of C from the upper ocean-atmosphere system to the deep ocean where the C is removed from contact with the atmosphere for an extended period of time. This C removal can be equated to the amount of C fixation by phytoplankton minus the C cycling and regeneration in the euphotic zone. If the regeneration efficiency is increased, then despite increased C fixation, no net loss (sequestration) of C will result. A reduction in cycling efficiency in the euphotic zone, on the other hand, will increase the effectiveness of the “biological pump” and thus C sequestration. The degree of organic matter biodegradation and recycling depends on the “reactivity” of compounds synthesized by the biota, which in turn, is controlled by the structural characteristic of these compounds. There is considerable evidence that different phytoplankton taxa differ substantially in their biogeochemical characteristics and it is likely that the relative abundance of different compounds synthesized by these distinct taxa, and even within each group at different growth conditions, will differ too. This variability in biosynthesis and thus abundance of a wide range of organic compounds in the water column would lend itself to different susceptibility for biodegradation and regeneration. Knowledge of the distribution of various organic matter structural groups synthesized by distinct taxa, the dependence of the organic matter compound classes on different growth conditions (temperature, light, nutrients) and the selective susceptibility of these compound to regeneration is crucial for estimating the potential for rapid regeneration in the euphotic zone, and thus the effectiveness of the “biological pump”.

Paytan, Adina [UCSC] [UCSC

2014-02-19T23:59:59.000Z

99

Biological removal of organic constituents in quench water from a slagging, fixed-bed coal-gasification pilot plant  

SciTech Connect

This study is part of an effort to assess the efficiency of activated-sludge treatment for removal of organic constituents from high-Btu coal-gasification pilot-plant quench waters. A sample of raw-gas quench water was obtained from the Grand Forks Energy and Technology Center's pilot plant, which employs the slagging, fixed-bed gasification process. The quench water generated in the processing of Indian Head lignite was pretreated to reduce ammonia and alkalinity, and then diluted and subjected to long-term biological treatment, followed by detailed characterization and analysis of organic constituents. The pretreated (influent) and treated (effluent) samples were extracted using a methylene chloride, pH-fractionation method to obtain acid, base, and neutral fractions, which were analyzed by capillary-column gas chromatography/mass spectrometry (GC/MS). Over 99% of the total extractable and chromatographable organic material in the influent acid fraction was composed of phenol and alkylated phenols. Biological treatment removed these compounds almost completely. Major components of the influent base fraction were alkylated pyridines, anilines, aminopyrroles, imidazoles and/or pyrazoles, diazines, and quinolines. Removal efficiency of these compounds ranged between 90 and 100%. The influent neutral fraction was composed mainly of cycloalkanes, cycloalkenes, naphthalene, indole, acetophenone, and benzonitrile. Alkylated benzenes were generally absent. Removal efficiencies of these compounds were generally very good, except for certain alkylated cycloalkanes and cycloalkenes. Results are compared with those of a similar study on HYGAS coal-gasification quench water.

Stamoudis, V C; Luthy, R G

1980-02-01T23:59:59.000Z

100

Introducing Bond-Line Organic Structures in High School Biology: An Activity That Incorporates Pleasant-Smelling Molecules  

Science Journals Connector (OSTI)

General Public; High School/Introductory Chemistry; Biochemistry; Interdisciplinary/Multidisciplinary; Organic Chemistry; Computer-Based Learning; Inquiry-Based/Discovery Learning; Food Science; Nomenclature/Units/Symbols ... In addition to its development in our own high school classes, this activity has been implemented by biology teachers at other high schools. ... This project was developed and performed while the authors Andro Rios (Socrates Fellow) and Gerald French (Mentor Teacher) were supported by a National Science Foundation GK-12 grant (NSF 0742551) to the University of California, San Diego (Principal Investigator, Maarten J. Chrispeels). ...

Andro C. Rios; Gerald French

2011-05-06T23:59:59.000Z

Note: This page contains sample records for the topic "organisms synthetic biology" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


101

What is compost? Composting refers to biological decomposition and stabilization of organic materials by microorganisms under  

E-Print Network (OSTI)

. These excess nutrients could lead to negative water-quality impacts. The blending of compost with wood chips process, heat produced biologically under proper moisture and aeration conditions accelerates and other micronutrients), pH and soluble salt content of compost before selecting and establishing its

Mukhtar, Saqib

102

Biology has been undergoing revolutionary changes in recent decades. Many problems once handled only descriptively are now analyzed at the molecular level using powerful  

E-Print Network (OSTI)

and biotechnology, cell and developmental biology, genetics of model organism systems, neuroscience, microbiologySciences ·Microbiology ·MolecularMechanismsofAging ·Nanobiology&Nanotechnology ·Neuroscience ·StemCellBiology ·Synthetic and statistical mechanics. susan P. gilbert Department Head Structure and mechanisms of microtubule

Linhardt, Robert J.

103

The effect of low concentrations of assimilable organic carbon (AOC) in water on biological clogging of sand beds  

Science Journals Connector (OSTI)

Infiltration of pretreated surface water with recharge wells is hampered by biological clogging processes in the aquifer. The influence of the concentration of easily assimilable organic carbon (AOC) in water on clogging was investigated in filter beds operated under well-defined laboratory conditions using acetate as a model substrate. Acetate concentrations in the water as low as 0.01 mg C/l promoted clogging with the main head loss, caused by bacterial growth, in the first centimeter of the sand bed. An empirical model was developed describing a linear relationship between the operation period to reach a certain increase in head loss (TPi) and the reciprocal value of the acetate concentration or acetate load [Lac g C/ (m2 · d)] at a constant filtration rate. The rate of clogging, designated as the microbiological clogging factor (Cr), is defined by the slope of the linear relationship between the square root of the increase of the head loss (P112) and the operation time. This linear relationship demonstrated that the increase in clogging rate was constant with time. Observations at several locations with experimental recharge wells revealed that the AOC concentration is an important parameter for the biological clogging potential of water. The AOC concentration of water used for infiltration in a recharge well should be less than 0.01 mg acetate-C equiv/l to prevent biological clogging for a period of more than a year.

W.A.M. Hijnen; D. Van der Koou

1992-01-01T23:59:59.000Z

104

Biological Processes  

Science Journals Connector (OSTI)

Biology is a natural science concerned with the study of living organisms, including their coexistence in the environment. The habitats of humans and other living organisms coincide, and their activities influ...

Dr. Sergey M. Govorushko

2012-01-01T23:59:59.000Z

105

A. Malcolm Campbell Biology and GCAT  

E-Print Network (OSTI)

? Application of engineering principles and mathematical modeling to the design and construction of biological parts, devices, and systems with applications in energy, medicine, and technology. www.bio.davidson Algae CO -neutral2 1,000,000 gallons in 2008 #12;Synthetic Biology BiochemistrySynthetic Biology Biology

Campbell, A. Malcolm

106

Modular Design of Artificial Tissue Homeostasis: Robust Control through Synthetic Cellular Heterogeneity  

E-Print Network (OSTI)

Synthetic biology efforts have largely focused on small engineered gene networks, yet understanding how to integrate multiple synthetic modules and interface them with endogenous pathways remains a challenge. Here we present ...

Miller, Miles Aaron

107

113 Lab Learning Objectives Week 5: synthetic lab #4  

E-Print Network (OSTI)

113 Lab Learning Objectives Week 5: synthetic lab #4 Learning Objectives for Promoter Discovery the information contained within promoters. · Use protocols for molecular biology to clone DNA. · Interpret

Campbell, A. Malcolm

108

A Synthetic Biology Framework for Programming Eukaryotic  

E-Print Network (OSTI)

coactivator/repressor complexes and basal transcriptional machinery, cooperating with other TFs to regulate of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA engineer complex functions, such as tunable output strength and transcriptional cooperativity

Khalil, Ahmad S.

109

Bayesian design strategies for synthetic biology  

Science Journals Connector (OSTI)

...3-5]. Here, after specification of the design objectives-e...effects (owing to thermal effects and the small...e. there is no insulation between different...dynamics that fulfil our specifications. In either case...their respective prior specifications; they naturally strike...

2011-01-01T23:59:59.000Z

110

Downward causation by information control in micro-organisms  

Science Journals Connector (OSTI)

...re-analyse published experiments of microbiology and synthetic biology that demonstrate...can be experimentally established in microbiology and synthetic biology. We then review...biochem.78.070507.135656 ) 45 Gilbert, S. D. , Rambo, R. P., Van Tyne...

2012-01-01T23:59:59.000Z

111

DNA Meta-Molecules: Synthe4c Biology via DNA Nanostructures &  

E-Print Network (OSTI)

reaction - DNA walkers - Activatable tiles and assemblies (4) DNA-based synthetic biology (slides 107-122) - Synthetic biology - DNA-based meta molecules and their use in synthetic biology - Meta DNA #12;SelfDNA Meta-Molecules: Synthe4c Biology via DNA Nanostructures & Hybridiza4on Reac

Reif, John H.

112

Formalizing Synthetic Domain Theory  

Science Journals Connector (OSTI)

Synthetic Domain Theory (SDT) is a constructive variant of Domain Theory where all functions are continuous following Dana Scott‘s idea of “domains as sets”. Recently there have been suggested more abstract axiomatizations encompassing ... Keywords: LCF, domain theory, formal verification, programming logics, synthetic domain theory, type theory

Bernhard Reus

1999-11-01T23:59:59.000Z

113

Organization  

NLE Websites -- All DOE Office Websites (Extended Search)

Organization Print Organization Print 2012-12 org chart A complete ALS organization chart (June 2013) is available in PDF. Appointed and elected members of advisory panels provide guidance to Berkeley Lab and ALS management in developing the ALS scientific and user programs. ALS Staff Photo staff photo thumb Click on the image to see a recent photo of ALS staff in front of the dome. The photo was taken on May 14, 2013. ALS Management and Advisory Team Steve Kevan, Deputy Division Director, Science Michael J. Banda, Deputy Division Director, Operations Robert W. Schoenlein, Senior Staff Scientist, Next Generation Light Source Initiative Janos Kirz, Scientific Advisor Paul Adams, Division Deputy for Biosciences ALS Scientific, Technical, and User Support Groups Accelerator Physics

114

Synthetic heparin-binding factor analogs  

DOE Patents (OSTI)

The invention provides synthetic heparin-binding growth factor analogs having at least one peptide chain, and preferably two peptide chains branched from a dipeptide branch moiety composed of two trifunctional amino acid residues, which peptide chain or chains bind a heparin-binding growth factor receptor and are covalently bound to a non-signaling peptide that includes a heparin-binding domain, preferably by a linker, which may be a hydrophobic linker. The synthetic heparin-binding growth factor analogs are useful as pharmaceutical agents, soluble biologics or as surface coatings for medical devices.

Pena, Louis A. (Poquott, NY); Zamora, Paul O. (Gaithersburg, MD); Lin, Xinhua (Plainview, NY); Glass, John D. (Shoreham, NY)

2010-04-20T23:59:59.000Z

115

Use of thermal analysis techniques (TG-DSC) for the characterization of diverse organic municipal waste streams to predict biological stability prior to land application  

SciTech Connect

Highlights: Black-Right-Pointing-Pointer Thermal analysis was used to assess stability and composition of organic matter in three diverse municipal waste streams. Black-Right-Pointing-Pointer Results were compared with C mineralization during 90-day incubation, FTIR and {sup 13}C NMR. Black-Right-Pointing-Pointer Thermal analysis reflected the differences between the organic wastes before and after the incubation. Black-Right-Pointing-Pointer The calculated energy density showed a strong correlation with cumulative respiration. Black-Right-Pointing-Pointer Conventional and thermal methods provide complimentary means of characterizing organic wastes. - Abstract: The use of organic municipal wastes as soil amendments is an increasing practice that can divert significant amounts of waste from landfill, and provides a potential source of nutrients and organic matter to ameliorate degraded soils. Due to the high heterogeneity of organic municipal waste streams, it is difficult to rapidly and cost-effectively establish their suitability as soil amendments using a single method. Thermal analysis has been proposed as an evolving technique to assess the stability and composition of the organic matter present in these wastes. In this study, three different organic municipal waste streams (i.e., a municipal waste compost (MC), a composted sewage sludge (CS) and a thermally dried sewage sludge (TS)) were characterized using conventional and thermal methods. The conventional methods used to test organic matter stability included laboratory incubation with measurement of respired C, and spectroscopic methods to characterize chemical composition. Carbon mineralization was measured during a 90-day incubation, and samples before and after incubation were analyzed by chemical (elemental analysis) and spectroscopic (infrared and nuclear magnetic resonance) methods. Results were compared with those obtained by thermogravimetry (TG) and differential scanning calorimetry (DSC) techniques. Total amounts of CO{sub 2} respired indicated that the organic matter in the TS was the least stable, while that in the CS was the most stable. This was confirmed by changes detected with the spectroscopic methods in the composition of the organic wastes due to C mineralization. Differences were especially pronounced for TS, which showed a remarkable loss of aliphatic and proteinaceous compounds during the incubation process. TG, and especially DSC analysis, clearly reflected these differences between the three organic wastes before and after the incubation. Furthermore, the calculated energy density, which represents the energy available per unit of organic matter, showed a strong correlation with cumulative respiration. Results obtained support the hypothesis of a potential link between the thermal and biological stability of the studied organic materials, and consequently the ability of thermal analysis to characterize the maturity of municipal organic wastes and composts.

Fernandez, Jose M., E-mail: joseman@sas.upenn.edu [Department of Earth and Environmental Science, University of Pennsylvania, Philadelphia, PA 19104-6316 (United States); Plaza, Cesar; Polo, Alfredo [Instituto de Ciencias Agrarias, Consejo Superior de Investigaciones Cientificas, Serrano 115 dpdo., 28006 Madrid (Spain); Plante, Alain F. [Department of Earth and Environmental Science, University of Pennsylvania, Philadelphia, PA 19104-6316 (United States)

2012-01-15T23:59:59.000Z

116

Highly Sensitive in Vitro Selections for DNA-Linked Synthetic Small Molecules with Protein Binding Affinity and Specificity  

E-Print Network (OSTI)

Highly Sensitive in Vitro Selections for DNA-Linked Synthetic Small Molecules with Protein Binding oligonucleotides to corresponding synthetic molecules, either as a consequence of DNA-templated organic synthesis3 or as a result of conjugating DNA to synthetic molecules, in theory enables synthetic molecules to satisfy

Liu, David R.

117

Synthetic Methods of Organic Chemistry A Thesaurus  

Science Journals Connector (OSTI)

... Swiss edition and the appearance of its translation. The work is described as a "Thesaurus", a word which is defined by the Shorter Oxford English Dictionary as meaning a ...

J. W. COOK

1948-08-07T23:59:59.000Z

118

Effect of synthetic conditions on the properties of methyltrimethoxysilane-based aerogels  

Science Journals Connector (OSTI)

The effect of synthetic conditions on the properties of methyltrimethoxysilane-based aerogels is reported. All of the aerogels are hydrophobic and can efficiently adsorb organic...

S. A. Lermontov; N. A. Sipyagina; A. N. Malkova…

2014-12-01T23:59:59.000Z

119

Heuristic for Maximizing DNA Reuse in Synthetic DNA Library Assembly  

Science Journals Connector (OSTI)

Heuristic for Maximizing DNA Reuse in Synthetic DNA Library Assembly ... In concert with entirely de novo synthesis, a swathe of alternative DNA assembly methods are being introduced(4-6) that concatenate parts from hundreds of base pairs in length, through gene fusions, to synthetic biological devices built from catalogued parts, up to megabase fragments and entire chromosomes. ... De novo synthesis relies on synthetic oligos that are inherently error prone, and therefore, reusing existing error-free DNA in constructing new DNA provides an inherent advantage. ...

Jonathan Blakes; Ofir Raz; Uriel Feige; Jaume Bacardit; Pawe? Widera; Tuval Ben-Yehezkel; Ehud Shapiro; Natalio Krasnogor

2014-02-20T23:59:59.000Z

120

WHAT IS COMPOST? Composting refers to the biological decomposition and stabilization of organic materials by microorganisms under  

E-Print Network (OSTI)

. The blending of compost with wood chips as an erosion-control blanket material may reduce the amount process, biologically produced heat under proper moisture and aeration conditions, accelerates. #12;analyze the nutrient (N, P, K and other micronutrients), pH and soluble salt content

Mukhtar, Saqib

Note: This page contains sample records for the topic "organisms synthetic biology" from the National Library of EnergyBeta (NLEBeta).
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they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


121

Biodegradable synthetic bone composites  

DOE Patents (OSTI)

The invention provides for a biodegradable synthetic bone composition comprising a biodegradable hydrogel polymer scaffold comprising a plurality of hydrolytically unstable linkages, and an inorganic component; such as a biodegradable poly(hydroxyethylmethacrylate)/hydroxyapatite (pHEMA/HA) hydrogel composite possessing mineral content approximately that of human bone.

Liu, Gao; Zhao, Dacheng; Saiz, Eduardo; Tomsia, Antoni P.

2013-01-01T23:59:59.000Z

122

Fatty Acids from Lipids of Marine Organisms: Molecular Biodiversity, Roles as Biomarkers, Biologically Active Compounds, and Economical Aspects  

Science Journals Connector (OSTI)

Because of their characteristic living environments, marine organisms produce a variety of lipids. Fatty acids constitute the essential part of triglycerides and wax esters, which are the major components ...

Jean-Pascal Bergé; Gilles Barnathan

2005-01-01T23:59:59.000Z

123

Life after the synthetic cell Natureaskedeightsynthetic-biologyexpertsabouttheimplicationsforscienceandsocietyofthe"synthetic  

E-Print Network (OSTI)

already had confidence in our ability to make synthetic DNA and get it to function in cells. The grandLife after the synthetic cell Natureaskedeightsynthetic-biologyexpertsabouttheimplicationsforscienceandsocietyofthe"synthetic"madebytheJ.CraigVenterInstitute(JCVI).Theinstitute'steamassembled,modifiedandimplanteda synthesizedgenomeintoaDNA-freebacterialshelltomakeaself-replicatingMycoplasmamycoides. The power and the pitfalls Mark

Goldberg, Bennett

124

Synthetic Rubber Production in Canada  

Science Journals Connector (OSTI)

... called the Polymer Corporation, Ltd., with headquarters in Toronto, which will undertake the production in Canada of synthetic ... in Canada of synthetic rubber of the Buna type. According to the Ottawa correspondent of The Times, Mr. ...

1942-03-21T23:59:59.000Z

125

Synthetic DNA Arrays  

Science Journals Connector (OSTI)

Analytical techniques that exploit the phenomenon of sequence-specific hybridization between nucleic acids have been workhorses of modern molecular biology. With the exponentially increasing rate of genomic seque...

Alan Blanchard

1998-01-01T23:59:59.000Z

126

Synthetic incoherent feedforward circuits show adaptation to the amount of their genetic template  

E-Print Network (OSTI)

Synthetic incoherent feedforward circuits show adaptation to the amount of their genetic template.12.10; accepted 6.6.11 Natural and synthetic biological networks must function reliably in the face of fluctuating expression efficiency and the DNA template amount of the network-coding genes. Gene product levels could

Sontag, Eduardo

127

Dissolution of Uranium-Bearing Minerals and Mobilization of Uranium by Organic Ligands in a Biologically Reduced Sediment  

SciTech Connect

The stability and mobility of uranium (U) is a concern following its reductive precipitation or immobilization by techniques such as bioremediation at contaminated sites. In this study, the influences of complexing organic ligands such as citrate and ethylenediaminetetraacetate (EDTA) on the mobilization of U were investigated in both batch and column flow systems using a contaminated and bioreduced sediment. Results indicate that both reduced U(IV) and oxidized U(VI) in the sediment can be effectively mobilized with the addition of EDTA or citrate under anaerobic conditions. The dissolution and mobilization of U appear to be correlated to the dissolution of iron (Fe)- or aluminum (Al)-bearing minerals, with EDTA being more effective (with R2 0.89) than citrate (R2 <0.60) in dissolving these minerals. The column flow experiments confirm that U, Fe, and Al can be mobilized by these ligands under anoxic conditions, although the cumulative amounts of U removal constituted ~0.1% of total U present in this sediment following a limited period of leaching. This study concludes that the presence of complexing organic ligands may pose a long-term concern by slowly dissolving U-bearing minerals and mobilizing U even under a strict anaerobic environment.

Luo, Wensui [ORNL; Gu, Baohua [ORNL

2011-01-01T23:59:59.000Z

128

Radiance: Synthetic Imaging System | Open Energy Information  

Open Energy Info (EERE)

Radiance: Synthetic Imaging System Radiance: Synthetic Imaging System Jump to: navigation, search Tool Summary Name: RADIANCE Agency/Company /Organization: Lawrence Berkeley National Laboratory Sector: Energy Focus Area: Buildings Resource Type: Software/modeling tools User Interface: Desktop Application Website: radsite.lbl.gov/radiance/ Cost: Free References: Radiance[1] Logo: RADIANCE RADIANCE is a highly accurate ray-tracing software system for UNIX computers that is licensed at no cost in source form. Radiance was developed with primary support from the U.S. Department Of Energy and additional support from the Swiss Federal Government. Radiance is a suite of programs for the analysis and visualization of lighting in design. Input files specify the scene geometry, materials, luminaires,time, date

129

DISTRIBUTED AND COLLABORATIVE SYNTHETIC ENVIRONMENTS  

E-Print Network (OSTI)

the functions required for the geometric engine of a synthetic environment system. · A distribution on networked desktop machines. Geometric Engine A critical subsystem in all synthetic environment systems is the geometric engine, or the software module responsible for creating a realistic view of the simulated world

Texas at Austin, University of

130

Marine Biology  

E-Print Network (OSTI)

this  door. ”   Marine  Biology   I  joined  the  military  RIVERSIDE   Marine  Biology   A Thesis submitted in partialBiology                                                                                                                        

Zaffino, Kyle

2013-01-01T23:59:59.000Z

131

SC e-journals, Biology/Genetics  

Office of Scientific and Technical Information (OSTI)

Biology/Genetics Biology/Genetics ACM Transactions on Applied Perception (TAP) ACS Chemical Biology ACS Synthetic Biology Acta Biotheoretica Acta Neuropathologica Advances in Bioinformatics - OAJ Advances in Health Sciences Education Agriculture and Human Values Agroforestry Systems American Journal of Agricultural and Biological Science - OAJ American Journal of Medical Genetics Amino Acids Analyst Analytical and Bioanalytical Chemistry Analytical Biochemistry Anatomical Record, The Anatomy and Embryology Angiogenesis Animal Biology Animal Cognition Annals of The ICRP Annual Review of Biochemistry Annual Review of Biomedical Engineering Annual Review of Biophysics Annual Review of Cell and Developmental Biology Annual Review of Entomology Annual Review of Genetics Annual Review of Genomics and Human Genetics

132

Synthetic and Mechanistic Chemistry publications  

NLE Websites -- All DOE Office Websites (Extended Search)

Synthetic and Mechanistic Chemistry » Synthetic and Mechanistic Chemistry » Synthetic and Mechanistic Synthetic and Mechanistic publications Research into alternative forms of energy, especially energy security, is one of the major national security imperatives of this century. Get Expertise Dave Thorn Chemistry Program Manager Email Josh Smith Chemistry Communications Email "Research into alternative forms of energy, of which biofuels is a key component, is one of the major national security imperatives of this century. Energy security is vital to our future national security and the efficient functioning of our market economy." -LANL Director Charles McMillan Harshini Mukundan, Hongzhi Xie, Aaron S. Anderson, W. Kevin Grace, John E. Shively, and Basil I. Swanson, "Optimizing a waveguide-based sandwich immunoassay for tumor biomarkers: Evaluating fluorescent labels and functional surfaces," Bioconjugate Chemistry 20(2), 222-230 (2009).

133

Exoelectron Emission from Synthetic Corundums  

Science Journals Connector (OSTI)

...Radiation Protection Dosimetry Article Exoelectron Emission from Synthetic Corundums M. Yousif Charif R. Gout J. Barthe M. Petel Corundums (Alpha Al2O3) have been synthesised by the thermal dehydration of hydrargilite (Al2O3, H2O......

M. Yousif Charif; R. Gout; J. Barthe; M. Petel

1983-05-01T23:59:59.000Z

134

Monomers for Synthetic Rubber Production  

Science Journals Connector (OSTI)

The purpose of this chapter is to describe briefly industrial processes for the manufacture of the more common of the olefinic monomers which are used in the production of synthetic rubbers. Some indication of th...

D. C. Blackley B.Sc.; Ph.D.; F.P.R.I.

1983-01-01T23:59:59.000Z

135

BIOLOGICAL SCIENCES Contemporary biological science  

E-Print Network (OSTI)

BIOLOGICAL SCIENCES Contemporary biological science covers a range of diverse and overlapping in cellular and molecular biology. Wichita State University's Department of Biological Sciences offers courses in most aspects of contemporary biological science. Our required core courses will expose you

136

STRUCTURAL CHANGE AND LEARNING WITHIN ORGANIZATIONS  

E-Print Network (OSTI)

Change and Learning Within Organizations". In Dynamics of organizational societies : Models, theories to organizational learning. This approach defines learning, culture, structure and behavior at the individual and organizational level. When organizations, as synthetic agents learn important organizational behaviors emerge

Sadeh, Norman M.

137

In Vitro Synthetic Transcriptional Networks Jongmin Kim  

E-Print Network (OSTI)

, we engineered artificial tran- scriptional networks consisting of synthetic DNA switches, regulated

Winfree, Erik

138

Synthetic Studies Toward Selected Members of the Pyrrole-imidazole Alkaloids: Axinellamine, Konbu’acidin and Palau' amine  

E-Print Network (OSTI)

cases, significant biological activities, have made these alkaloids the synthetic targets of a number of research groups across the world. In our approach, following early biosynthetic proposal by Kinnel and Scheuer and Al-Mourabit and Potier...

Zancanella, Manuel

2011-10-21T23:59:59.000Z

139

Assembly of BioBrick standard biological parts using three antibiotic assembly  

E-Print Network (OSTI)

An underlying goal of synthetic biology is to make the process of engineering biological systems easier and more reliable. In support of this goal, we developed BioBrick assembly standard 10 to enable the construction of ...

Shetty, Reshma

2011-05-20T23:59:59.000Z

140

Comparative Microbial Genomics group CenterforBiologicalSequenceAnalysisTheTechnicalUniversityofDenmarkDTU  

E-Print Network (OSTI)

Comparative Microbial Genomics group CenterforBiologicalSequenceAnalysisTheTechnicalUniversityofDenmarkDTU Minimal genomes in bacterial Genera Dave Ussery European Conference on Synthetic Biology: Design 2007 #12;Comparative Microbial Genomics group Centerfor

Ussery, David W.

Note: This page contains sample records for the topic "organisms synthetic biology" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


141

Towards synthetic biological approaches to resource utilization on space missions  

Science Journals Connector (OSTI)

...for an outpost on the lunar soil by means of a novel 3D printing technology. Acta Astronaut. 93, 430-450. ( doi...Ellsworth, M Snyder, WB White, and BR Blair. 2010 3D printing in space: enabling new markets and accelerating the...

2015-01-01T23:59:59.000Z

142

Marine-derived heterocycles : structural, synthetic and biological investigations  

E-Print Network (OSTI)

OMOM i) iPr 2 NP(OFm) 2 tetrazole MeCN/CH 2 Cl 2 , rt OBnO OAc i) iPr 2 NP(OFm) 2 tetrazole MeCN/CH 2 Cl 2 rt, 40 minmg, 0.0021 mmol) and tetrazole (4.34 mg, 0.0062 mmol, 183 µL

Skepper, Colin K.

2009-01-01T23:59:59.000Z

143

Marine-derived heterocycles : structural, synthetic and biological investigations  

E-Print Network (OSTI)

3 ]•CHCl 3 (4-CH 3 OPh) 3 P, iPr 2 NEt DMF, 80 °C SnBu 3 COnuclear Overhauser effect iPr isopropyl PG protecting groupO O TBSO i) 1.23, TiCl 4 , iPr 2 NEt CH 2 Cl 2 , ! 20 °C ii)

Skepper, Colin K.

2009-01-01T23:59:59.000Z

144

Towards synthetic biological approaches to resource utilization on space missions  

Science Journals Connector (OSTI)

...nutrient mass. Second, nutrient recycling is already an active research...substantial (greater than 65%) recycling efficiencies for potassium...and AA Tikhomirov. 2003 Recycling efficiencies of C, H, O...harvesting of microalgae for wastewater treatment, biofuels, and...

2015-01-01T23:59:59.000Z

145

Marine-derived heterocycles : structural, synthetic and biological investigations  

E-Print Network (OSTI)

100 MHz, CDCl 3 ) of compound 4.88 f1 (ppm) H NMR (400 MHz,CDCl 3 ) of compound 4.89 f1 (ppm) H NMR (125 MHz,CDCl 3 ) of compound 4.89 f1 (ppm) f1 (ppm) H NMR (500 MHz,

Skepper, Colin K.

2009-01-01T23:59:59.000Z

146

Synthetic biology and biomass conversion: a match made in heaven?  

Science Journals Connector (OSTI)

...such as nuclear, solar-electric, solar-thermal, hydroelectric, geothermal...competition (iGEM 2008) hosted by the Massachusetts Institute of Technology testify to the...for standard assembly of BioBricks. Massachusetts Institute of Technology. See http...

2009-01-01T23:59:59.000Z

147

Synthetic Biology and reshaping plant form Jim Haseloff  

E-Print Network (OSTI)

Industrial Revolution: based on innovations in coal, iron, steam and mechanical engineering #12; Steam power machines.This enabled rapid development of e cient semi-automated factories Iron founding - Coke replaced

Rosso, Lula

148

Single Molecule and Synthetic Biology Studies of Transcription  

E-Print Network (OSTI)

R.J. et al. Single-molecule study of transcriptional pausingBustamante, C. Single molecule transcription elongation.RNA polymerase. A single-molecule view of the transcription

Zamft, Bradley Michael

2011-01-01T23:59:59.000Z

149

Synthetic Biology: Regulating Industry Uses of New Biotechnologies  

Science Journals Connector (OSTI)

...of computers. Much as earlier developments in somatic cell nuclear transfer were described with terms such as “reprogramming...to recent oil spills where large volumes of toxic chemical dispersants were used, Modular Genetics, Inc., of Cambridge, Mass...

Brent Erickson; Rina Singh; Paul Winters

2011-09-02T23:59:59.000Z

150

Synthetic Metabolism: Engineering Biology at the Protein and Pathway Scales  

E-Print Network (OSTI)

Biocatalysis has become a powerful tool for the synthesis of high-value compounds, particularly so in the case of highly functionalized and/or stereoactive products. Nature has supplied thousands of enzymes and assembled ...

Martin, Collin H.

151

Physical Characteristics of Synthetic Rubbers  

Science Journals Connector (OSTI)

A summary of the nature and special applications of the more important types of synthetic rubbers is given. Two series of rubber and synthetic rubber stocks compounded on the basis of comparable pigmentation were selected for study. In addition to the conventional physical properties (tensile strength and elongation at rupture modulus aging etc.) a number of other mechanical properties such as dynamic rigidity hysteresis loss ``blowout resistance '' ``running temperature '' and tensile strength at elevated temperature were measured. Swelling tests in various solvents were also made. Results are plotted in the form of correlation charts in an effort to select proper methods of measurement. Some observations on comparative service tests in tires in the case of three synthetic rubbers indicate them to be satisfactory on a quality basis for use in time of emergency. The importance of care in selecting the proper physical tests and methods of analysis is emphasized in the light of the results given. It is concluded that rubbertesting techniques and interpretation must be modified in certain instances in evaluating synthetic rubber stocks.

J. N. Street; J. H. Dillon

1941-01-01T23:59:59.000Z

152

Future Prospects of Synthetic Fuels  

E-Print Network (OSTI)

It is important for the future of this nation to reach the goal of demonstrated definition and quantification of the parameters which influence the ability to use this country's vast resources of coal and oil shale for production of synthetic fuels...

Fryback, M. G.

1982-01-01T23:59:59.000Z

153

Biological Applications of Synchrotron Radiation:  

NLE Websites -- All DOE Office Websites (Extended Search)

Biological Applications of Synchrotron Radiation: Biological Applications of Synchrotron Radiation: An Evaluation of the State of the Field in 2002 A BioSync Report. Issued by the Structural Biology Synchrotron users Organization, October, 2002. 2 Table of Contents: Introduction .................................................................................................... 3 Abbreviations .................................................................................................. 5 Executive Summary ......................................................................................... 6 General Concerns ............................................................................................ 9 Synchrotron operations and maintenance ............................................... 9 NSLS, CHESS and the geographical distribution of beam lines

154

Pioneer's name written in synthetic DNA  

Science Journals Connector (OSTI)

Craig Venter has “signed” his name into the sequence of the synthetic bacterial genome his lab created

2008-01-01T23:59:59.000Z

155

Synthetic LDL as targeted drug delivery vehicle  

DOE Patents (OSTI)

The present invention provides a synthetic LDL nanoparticle comprising a lipid moiety and a synthetic chimeric peptide so as to be capable of binding the LDL receptor. The synthetic LDL nanoparticle of the present invention is capable of incorporating and targeting therapeutics to cells expressing the LDL receptor for diseases associated with the expression of the LDL receptor such as central nervous system diseases. The invention further provides methods of using such synthetic LDL nanoparticles.

Forte, Trudy M. (Berkeley, CA); Nikanjam, Mina (Richmond, CA)

2012-08-28T23:59:59.000Z

156

Integrated processes for removal of persistent organic pollutants : soil washing and electrochemical advanced oxidation processes combined to a possible biological post-treatment.  

E-Print Network (OSTI)

??Soils contaminated by hydrophobic organic pollutants like polycyclic aromatic hydrocarbons (PAHs) are a common concern since they are extremely difficult to remove and their potential… (more)

Mousset, Emmanuel

2013-01-01T23:59:59.000Z

157

Toward engineering functional organ modules by additive manufacturing  

Science Journals Connector (OSTI)

Tissue engineering is emerging as a possible alternative to methods aimed at alleviating the growing demand for replacement tissues and organs. A major pillar of most tissue engineering approaches is the scaffold, a biocompatible network of synthetic or natural polymers, which serves as an extracellular matrix mimic for cells. When the scaffold is seeded with cells it is supposed to provide the appropriate biomechanical and biochemical conditions for cell proliferation and eventual tissue formation. Numerous approaches have been used to fabricate scaffolds with ever-growing complexity. Recently, novel approaches have been pursued that do not rely on artificial scaffolds. The most promising ones utilize matrices of decellularized organs or methods based on multicellular self-assembly, such as sheet-based and bioprinting-based technologies. We briefly overview some of the scaffold-free approaches and detail one that employs biological self-assembly and bioprinting. We describe the technology and its specific applications to engineer vascular and nerve grafts.

Francoise Marga; Karoly Jakab; Chirag Khatiwala; Benjamin Shepherd; Scott Dorfman; Bradley Hubbard; Stephen Colbert; Gabor Forgacs

2012-01-01T23:59:59.000Z

158

Synthetic pH Sensor, Protein Nanomaterials, Metabolites in Stem Cells, and DNA Barcodes  

Science Journals Connector (OSTI)

Each month, Chemistry & Biology Select highlights a selection of research reports from the recent literature. These highlights are a snapshot of interesting research done across the field of chemical biology, and this month's Select includes reports on a synthetic pH sensor, a tag that guides assembly of proteins into nanomaterials, a role of an intermediary metabolite in regulation of stem cells, and DNA-barcoded nucleosome libraries.

2014-01-01T23:59:59.000Z

159

Phosphate Tether-Mediated Synthetic Studies- Applications in Natural Products Synthesis.  

E-Print Network (OSTI)

biological activity, the interesting structural features of these seven-membered bicyclic enol-phosphate triesters, which possess a 7,5-fused butyrolactone ring and chirality at C3, as well as at phosphorus, have identified them as interesting synthetic...

Jayasinghe Mudiyanselage, Susanthi Jayasinghe

2012-08-31T23:59:59.000Z

160

Structure-Function Relationships in Semiconducting Polymers for Organic Photovoltaics  

E-Print Network (OSTI)

fundamental physics behind how conjugated organic molecules the optical and electronicFundamental investigations of how synthetic molecular manipulation alters the electronicfundamental operating mechanism of organic photovoltaic devices. New conjugated polymers were characterized and their optical and electronic

Kavulak, David Fredric Joel

2010-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "organisms synthetic biology" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


161

Method of producing synthetic pitch  

DOE Patents (OSTI)

Embodiments of a method are described for modifying pitches, oils, tars, and binders by using these materials as solvents to extract organic chemicals from coal.

Kennel, Elliot B. (Morgantown, WV); Stansberry, Peter G. (North Olmsted, OH); Stiller, Alfred H. (Morgantown, WV); Zondlo, John W. (Albright, WV)

2012-07-24T23:59:59.000Z

162

Definition: Interferometric Synthetic Aperture Radar | Open Energy  

Open Energy Info (EERE)

Interferometric Synthetic Aperture Radar Interferometric Synthetic Aperture Radar Jump to: navigation, search Dictionary.png Interferometric Synthetic Aperture Radar Interferometric Synthetic Aperture Radar (InSAR) utilizes SAR images from two different time periods to generate maps of surface deformation. The technique can potentially measure millimeter-scale changes in the Earth's surface.[1][2] View on Wikipedia Wikipedia Definition Also Known As InSAR, IfSAR Related Terms Synthetic Aperture Radar, radar, sustainability References ↑ Synthetic Aperture Radar Interferometry to Measure Earth's Surface Topography and Its Deformation (Burgmann et al. 2000) ↑ Improved Visulaization of Satellite Radar InSAR Observed Structural Controls at Producing Geothermal Field Using Modeled Horizontal Surface Displacements(Opplinger et al. 2006)

163

Materials from Renewable Resources Most synthetic organic materials and polymers  

E-Print Network (OSTI)

.sukumaran@che Conceptualize ecofriendly chemicals, solvents, surfactants, and liquid solutions for chemical and industrial processeschemical and industrial processes Play a pivotal role in benign ways of producing chemicals and solvents research partners Create a sustainable economy using green chemistry Impressum Herausgeber: Universität

Schubart, Christoph

164

Survey and Control of Synthetic Organics in Texas Water Supplies  

E-Print Network (OSTI)

was used as a surrogate for turbidity. Modification of conventional alum coagulation by addition of acid or base for pH control or by addition of secondary coagulants was studied. A medium molecular weight cationic polymer and activated silica were used...

Batchelor, B.; Shannon, J. D.; Yang, P.

165

New Design and Synthetic Strategies of Metal-Organic Frameworks  

E-Print Network (OSTI)

measured with Ar at 87K. ........................ 93 Figure 61. H2 gas sorption isotherm of PCN-94. ............................................................. 94 Figure 62. Coverage dependence of the isosteric heats of adsorption calculated from.... ................................................. 34 Figure 16. Coverage dependence of the isosteric heats of adsorption calculated from the isotherms for H2. ......................................................................................... 35 Figure 17. The CO2 isotherm of PCN-91at 273K...

Wei, Zhangwen

2014-04-18T23:59:59.000Z

166

Organic Synthesis in Japan: From Natural Products to Synthetic Control  

Science Journals Connector (OSTI)

...T. Sugimura, Gann 75, 113 (1984). 65. N. Ito, S. Fukushima, A. Hagiwara, M. Shibata, T. Ogiso,J. NatI. CancerInst...People living in countries 324 subject to major earthquakes look forward to the day when it will be possible to predict when and where...

TERUAKI MUKAIYAMA

1986-07-18T23:59:59.000Z

167

Engineering a Synthetic Dual-Organism System for Hydrogen Production  

Science Journals Connector (OSTI)

...promising renewable energy source as pressure...but they are also energy intensive and therefore...due to its use of renewable biomass or sunlight as its primary energy source. Hydrogen...due to the current cost of its chemical synthesis...

Zeev Waks; Pamela A. Silver

2009-02-06T23:59:59.000Z

168

A Synthetic DNA Walker for Molecular Transport  

Science Journals Connector (OSTI)

A Synthetic DNA Walker for Molecular Transport ... The authors report the incrementally staged design, synthesis, characterization, and operation of a mol. ...

Jong-Shik Shin; Niles A. Pierce

2004-08-17T23:59:59.000Z

169

Performance evaluation of synthetically lined landfills  

SciTech Connect

Landfill design and performance standards for new facilities frequently require the use of geomembrane composite and double liners. Performance data from synthetically lined landfill sites have not been widely available. This report presents data obtained by monitoring three recently constructed synthetically lined landfill sites. Quantities of leachate removed by the primary and secondary collection systems from these landfills were tabulated. The data show that properly designed and constructed synthetic landfill liners provide effective containment of leachate. The environmental protection provided by synthetic liners is equivalent or superior to that of typical clay-lined facilities.

Maule, J. [Champion International Corp., Norway, MI (United States); Lowe, R.K. [STS Consultants Ltd., Green Bay, WI (United States); McCulloch, J.L. [Cross Pointe Paper Co., Park Falls, WI (United States)

1993-12-01T23:59:59.000Z

170

The proper place of hopeful monsters in evolutionary biology  

Science Journals Connector (OSTI)

Hopeful monsters are organisms with a profound mutant phenotype that have the potential to establish a new evolutionary lineage. The Synthetic Theory of evolutionary biology has rejected the evolutionary relevance of hopeful monsters, but could not fully explain the mechanism and mode of macroevolution. On the other hand, several lines of evidence suggest that hopeful monsters played an important role during the origin of key innovations and novel body plans by saltational rather than gradual evolution. Homeotic mutants are identified as an especially promising class of hopeful monsters. Examples for animal and plant lineages that may have originated as hopeful monsters are given. Nevertheless, a brief review of the history of the concept of hopeful monsters reveals that it needs refinements and empirical tests if it is to be a useful addition to evolutionary biology. While evolutionary biology is traditionally zoocentric, hopeful monsters might be more relevant for plant than for animal evolution. Even though during recent years developmental genetics has provided detailed knowledge about how hopeful monsters can originate in the first place, we know almost nothing about their performance in natural populations and thus the ultimate difference between hopeful and hopeless. Studying the fitness of candidate hopeful monsters (suitable mutants with profound phenotype) in natural habitats thus remains a considerable challenge for the future.

Günter Theißen

2006-01-01T23:59:59.000Z

171

WithCarbonSequestration Biological-  

E-Print Network (OSTI)

WithCarbonSequestration Biomass Hydro Wind Solar Coal Nuclear Natural Gas Oil Biological BARRIERS · Cost · Feedstock availability · Fermentative micro-organisms #12;Targets and Status 322726Net

172

Preparation of synthetic hydrocarbon lubricants  

SciTech Connect

A process is described for preparing synthetic lubricating materials which process comprises: (a) reacting (i) at least a portion of a reaction product of the liquid phase oligomerization of propylene, butylene or mixtures thereof containing a C/sub 6/ olefin component, (ii) a linear olefin reactant having an average carbon number ranging from about 10 to about 18 in the presence of a catalyst, (b) separating from the reaction mixture of (a) hydrocarbons which distill at a temperature above about 660/sup 0/ F. (316/sup 0/ C.), and (c) hydrogenating the reaction product of (b) by contact with hydrogen with or without a catalyst at a temperature ranging from about 25/sup 0/ C. to about 300/sup 0/ C.

Johnson, T.H.

1986-10-07T23:59:59.000Z

173

Approaches for biological and biomimetic energy conversion  

Science Journals Connector (OSTI)

...biological and biomimetic energy conversion 10.1073...that are related to energy conversion: specifically...synthetic and/or hybrid devices is still...systems that produce energy in an efficient...costs are related to infrastructure, such as supporting...inverters, and grid connections. For...

David A. LaVan; Jennifer N. Cha

2006-01-01T23:59:59.000Z

174

Fracture of synthetic diamond M. D. Droty  

E-Print Network (OSTI)

Fracture of synthetic diamond M. D. Droty Ctystallume, 3506 Bassett Street, Santa Clara, California 1995) The fracture behavior of synthetic diamond has been investigated using indentation methods and by the tensile testing of pre-notched fracture-mechanics type samples. Specifically, the fracture toughness

Ritchie, Robert

175

BS in MOLECULAR BIOLOGY (285125) Map Sheet Department of Microbiology and Molecular Biology  

E-Print Network (OSTI)

Chem Laboratory Chem 351 Organic Chemistry Chem 352 Organic Chemistry Chem 353 Organic Chemistry Lab) Requirements Doctrinal Foundation Book of Mormon New Testament Doctrine and Covenants The Individual 120 Science of Biology PDBio 360 Cell Biology PWS 340* Genetics Complete the following chemistry

Olsen Jr., Dan R.

176

The Evolutionary Systems Biology Team Synthetic Biology/Citizen Science Post-doctoral position  

E-Print Network (OSTI)

-sourcing, DIY approaches and gamification as part of a new European- funded project, Citizen CyberLab - a three

177

Synthetic Promoters Functional in Francisella novicida and Escherichia coli  

Science Journals Connector (OSTI)

...facultative intracellular pathogen. Synthetic DNA fragments consisting of the tetracycline...controllable promoters from a library of synthetic DNA molecules. We show that the strongest...flanking BamHI restriction sites) synthetic DNA fragments with a nearly central...

Ralph L. McWhinnie; Francis E. Nano

2013-10-18T23:59:59.000Z

178

Building a metal-responsive promoter with synthetic regulatory elements.  

Science Journals Connector (OSTI)

...function of MREs, we inserted a synthetic DNA fragment containing the sequence...function of MREs, we inserted a synthetic DNA fragment containing the sequence...function of MREs, we inserted a synthetic DNA fragment containing the sequence...

P F Searle; G W Stuart; R D Palmiter

1985-06-01T23:59:59.000Z

179

Molecular Interactions of Plutonium(VI) with SyntheticManganese...  

NLE Websites -- All DOE Office Websites (Extended Search)

Plutonium(VI) with Synthetic Manganese-Substituted Goethite. Abstract: Plutonium(VI) sorption on the surface of well-characterized synthetic manganese-substituted goethite...

180

Sorption-Enhanced Synthetic Natural Gas (SNG) Production from...  

NLE Websites -- All DOE Office Websites (Extended Search)

Sorption-Enhanced Synthetic Natural Gas (SNG) Production from Syngas: A Novel Process Combining CO Methanation, Water-Gas Shift, Sorption-Enhanced Synthetic Natural Gas (SNG)...

Note: This page contains sample records for the topic "organisms synthetic biology" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


181

Function-based, biologically inspired concept generation  

Science Journals Connector (OSTI)

The natural world provides numerous cases for inspiration in engineering design. Biological organisms, phenomena, and strategies, which we refer to as biological systems, provide a rich set of analogies. These systems provide insight into sustainable ... Keywords: Biologically Inspired, Concept Generation, Engineering Design, Function-Based Design

Jacquelyn k. s. Nagel; Robert l. Nagel; Robert b. Stone; Daniel a. Mcadams

2010-11-01T23:59:59.000Z

182

Biological Safety  

Energy.gov (U.S. Department of Energy (DOE))

The DOE's Biological Safety Program provides a forum for the exchange of best practices, lessons learned, and guidance in the area of biological safety. This content is supported by the Biosurety Executive Team. The Biosurety Executive Team is a DOE-chartered group. The DOE Office of Worker Safety and Health Policy provides administrative support for this group. The group identifies biological safety-related issues of concern to the DOE and pursues solutions to issues identified.

183

Biological Systems  

NLE Websites -- All DOE Office Websites (Extended Search)

Biological Processing and Manufacturing The bioloical processing and manufacturing research being performed at the Idaho National Laboratory is primarily focused on using...

184

Definition: Synthetic Aperture Radar | Open Energy Information  

Open Energy Info (EERE)

Aperture Radar Aperture Radar Jump to: navigation, search Dictionary.png Synthetic Aperture Radar Synthetic-aperture radar (SAR) is an active microwave remote sensing technology that measures the phase difference between a radar wave emitted from an antennae attached to a satellite or aircraft to generate high-resolution images of a surface.[1] View on Wikipedia Wikipedia Definition Also Known As SAR Related Terms radar References ↑ Synthetic Aperature Radar: Systems and Signal Processing (Curlander and McDonough - 1991 - book) fue LikeLike UnlikeLike You like this.Sign Up to see what your friends like. l cell, Retrieved from "http://en.openei.org/w/index.php?title=Definition:Synthetic_Aperture_Radar&oldid=493069" Category: Definitions What links here Related changes

185

The assessment of DNA-synthetic activity  

Science Journals Connector (OSTI)

A method is described by which a numerical value can be assigned to the amount of DNA-synthesis shown graphically by population-histograms obtained ... index appeared to give a reasonable measure of DNA-synthetic

L. A. Coulton; B. Henderson; J. Chayen

1981-01-01T23:59:59.000Z

186

Recognition of DNA by Synthetic Antibodies  

Science Journals Connector (OSTI)

Recognition of DNA by Synthetic Antibodies ... The recombinant anti-ssDNA Fab, DNA-1, and 16 heavy chain complementarity determining region 3 (HCDR3) mutant variants were selected for thermodynamic characterization of ssDNA binding. ...

Shana M. Barbas; Peter Ghazal; Carlos F. Barbas III; Dennis R. Burton

1994-03-01T23:59:59.000Z

187

DNA interaction with synthetic polymers in solution  

Science Journals Connector (OSTI)

The complexes in which a DNA molecule is compact and protected from the ... lipids, inactivated viral particles, polymeric micelles and synthetic polycations are used [12–23...]. The latter have important advanta...

Nina Kasyanenko; Daria Afanasieva; Boris Dribinsky; Dmitry Mukhin…

2007-08-01T23:59:59.000Z

188

Iterative synthetic aperture radar imaging algorithms   

E-Print Network (OSTI)

Synthetic aperture radar is an important tool in a wide range of civilian and military imaging applications. This is primarily due to its ability to image in all weather conditions, during both the day and the night, ...

Kelly, Shaun Innes

2014-06-30T23:59:59.000Z

189

Fuzzy Synthetic Evaluation of Gas Station Safety  

Science Journals Connector (OSTI)

Based on the comprehensive analysis of hazard factors and evaluation indexes in gas stations, gas station safety is assessed in a fuzzy synthetic ... comprehensive evaluation, the specific safety level of gas stations

Xiaohua Hao; Xiao Feng

2010-01-01T23:59:59.000Z

190

Macroporous nanowire nanoelectronic scaffolds for synthetic tissues  

E-Print Network (OSTI)

The development of three-dimensional (3D) synthetic biomaterials as structural and bioactive scaffolds is central to fields ranging from cellular biophysics to regenerative medicine. As of yet, these scaffolds cannot ...

Tian, Bozhi

191

Effects of Mine Waste Contamination on Fish and Wildlife Habitat at Multiple Levels of Biological Organization in the Methow River, 2001-2002 Annual Report.  

SciTech Connect

A three-year multidisciplinary study was conducted on the relationship between mine waste contamination and the effects on aquatic and terrestrial habitats in the Methow River below abandoned mines near Twisp in Okanogan County, Washington (U.S.A.). Ore deposits in the area were mined for gold, silver, copper and zinc until the early 1950's. An above-and-below-mine approach was used to study potentially impacted sites. Although the dissolved metal content of water in the Methow River was below the limits of detection, eleven chemicals of potential environmental concern were identified in the tailings, mine effluents, groundwater, streamwater and sediments (Al, As, B, Ba, Cd, Cr, Cu, Mn, Pb, Se and Zn). The potential for ecosystem level impacts was reflected in the risk of contamination in the mine waste to communities and populations that are valued for their functional properties related to energy storage and nutrient cycling. Dissolved and sediment metal contamination changed the benthic insect community structure in a tributary of the Methow River below Alder Mine, and at the population level, caddisfly larval development in the Methow River was delayed. Arsenic accumulation in bear hair and Cd in fish liver suggest top predators are effected. In situ exposure of juvenile triploid trout (Oncorhynchus mykiss) to conditions at the downstream site resulted in reduced growth and increased mortality among exposed individuals. Histopathological studies of their tissues revealed extensive glycogen inclusions suggesting food is being converted into glycogen and stored in the liver but the glycogen is not being converted back normally into glucose for distribution to other tissues in the body. Subcellular observations revealed mitochondrial changes including a decrease in the number and increase in the size of electron-dense metrical granules, the presence of glycogen bodies in the cytoplasm, and glycogen nuclei in exposed trout hepatocytes, which are signs that Type IV Glycogen Storage disease is occurring. GSD IV is caused by either a deficiency or inactivation of the glycogen branching enzyme that results in the synthesis of an abnormal glycogen molecule that is insoluble and has decreased branch points and increased chain length. These results show that the effects of mine waste contaminants can be expressed at all levels of organization from molecular to ecosystem-level responses.

Peplow, Dan; Edmonds, Robert.

2002-06-01T23:59:59.000Z

192

Synthetic Datasets Rong Huang, Rada Chirkova, Yahya Fathi  

E-Print Network (OSTI)

Synthetic Datasets Rong Huang, Rada Chirkova, Yahya Fathi 1 Introduction Datasets may be generated will define symmetric synthetic dataset and two types of non-symmetric synthetic datasets that has some introduce symmetric synthetic dataset, its structure and the properties of the associated views. In Section

Young, R. Michael

193

An increasing number of synthetic compounds have been shown to facilitate ion and polar molecule transport across  

E-Print Network (OSTI)

transport of ions and polar molecules across biological membranes is essential for normal cell function synthetic transporters shown to be active in both model bilayers and cellular membranes. Mechanism of ion simulations of unassisted Na+ and Cl­ ion transport across a bilayer membrane. As the ion enters the outer

Smith, Bradley D.

194

Structural biology  

Science Journals Connector (OSTI)

...systematic attempt to 1980 K. C. Holmes Structural biology...structural genomics (Shapiro & Lima 1998). The purpose...Rosenbaum, G., Holmes, K. C. & Witz, J. 1971 Synchrotron...95, 13 585^13590. Shapiro, L. & Lima, C. D. 1998 The Argonne...

1999-01-01T23:59:59.000Z

195

Collaborative Networks for Biodiversity Domain Organizations  

E-Print Network (OSTI)

, conservation groups, etc., referred to in this paper as BOs (Biodiversity-domain OrganizationsCollaborative Networks for Biodiversity Domain Organizations Ekaterina Ermilova, Hamideh, operating in the domains of biology, ecology, and biodiversity, strongly need to cooperate

Boyer, Edmond

196

New lithium cuprates for the promotion of directed organic transformations  

E-Print Network (OSTI)

The use of bimetallic bases to effect highly stereoselective organic transformations via Directed ortho Metalation (DoM) is an important synthetic tool and requires thorough investigation to maximise efficiency and develop a mechanistic...

Harford, Philip James

2014-10-07T23:59:59.000Z

197

Novel Aryne Chemistry in Organic Synthesis  

SciTech Connect

Arynes are among the most intensively studied systems in chemistry. However, many aspects of the chemistry of these reactive intermediates are not well understood yet and their use as reagents in synthetic organic chemistry has been somewhat limited, due to the harsh conditions needed to generate arynes and the often uncontrolled reactivity exhibited by these species. Recently, o-silylaryl triflates, which can generate the corresponding arynes under very mild reaction conditions, have been found very useful in organic synthesis. This thesis describes several novel and useful methodologies by employing arynes, which generate from o-silylaryl triflates, in organic synthesis. An efficient, reliable method for the N-arylation of amines, sulfonamides and carbamates, and the O-arylation of phenols and carboxylic acids is described in Chapter 1. Amines, sulfonamides, phenols, and carboxylic acids are good nucleophiles, which can react with arynes generated from a-silylaryl triflates to afford the corresponding N- and O-arylated products in very high yields. The regioselectivity of unsymmetrical arynes has also been studied. A lot of useful, functional groups can tolerate our reaction conditions. Carbazoles and dibenzofurans are important heteroaromatic compounds, which have a variety of biological activities. A variety of substituted carbazoles and dibenzofwans are readily prepared in good to excellent yields starting with the corresponding o-iodoanilines or o-iodophenols and o-silylaryl triflates by a treatment with CsF, followed by a Pd-catalyzed cyclization, which overall provides a one-pot, two-step process. By using this methodology, the carbazole alkaloid mukonine has been concisely synthesized in a very good yield. Insertion of an aryne into a {sigma}-bond between a nucleophile and an electrophile (Nu-E) should potentially be a very beneficial process from the standpoint of organic synthesis. A variety of substituted ketones and sulfoxides have been synthesized in good yields via the intermolecular C-N {sigma}-bond addition of amides and S-N {sigma}-bond addition of sulfinamides to arynes under mild reaction conditions. The indazole moiety is a frequently found subunit in drug substances with important biological activities. Indazole analogues have been readily synthesized under mild reaction conditions by the [3+2] cycloaddition of a variety of diazo compounds with o-silylaryl triflates in the presence of CsF or TBAF. Polycyclic aromatic and heteroaromatic hydrocarbons have been synthesized in high yields by two different processes involving the Pd-catalyzed annulation of arynes. Both processes appear to involve the catalytic, stepwise coupling of two very reactive substrates, an aryne and an organopalladium species, to generate excellent yields of cross-coupled products.

Zhijian Liu

2006-12-12T23:59:59.000Z

198

Biological preconcentrator  

DOE Patents (OSTI)

A biological preconcentrator comprises a stimulus-responsive active film on a stimulus-producing microfabricated platform. The active film can comprise a thermally switchable polymer film that can be used to selectively absorb and desorb proteins from a protein mixture. The biological microfabricated platform can comprise a thin membrane suspended on a substrate with an integral resistive heater and/or thermoelectric cooler for thermal switching of the active polymer film disposed on the membrane. The active polymer film can comprise hydrogel-like polymers, such as poly(ethylene oxide) or poly(n-isopropylacrylamide), that are tethered to the membrane. The biological preconcentrator can be fabricated with semiconductor materials and technologies.

Manginell, Ronald P. (Albuquerque, NM); Bunker, Bruce C. (Albuquerque, NM); Huber, Dale L. (Albuquerque, NM)

2008-09-09T23:59:59.000Z

199

Nanoscale Molecular Transport by Synthetic DNA Machines  

E-Print Network (OSTI)

Nanoscale Molecular Transport by Synthetic DNA Machines Jong-Shik Shin1 and Niles A. Pierce1,2 1 a processive bipedal DNA walker. Powered by externally controlled DNA fuel strands, the walker locomotes with a 5 nm stride by advancing the trailing foot to the lead at each step. On a periodic DNA track

Pierce, Niles A.

200

Synthetic fuels, carbon dioxide and climate  

Science Journals Connector (OSTI)

The observed increase in atmospheric carbon dioxide (CO2) has been attributed to the use of fossil fuels. There is concern that the generation and use of synthetic fuels derived from oil shale and coal will accelerate the increase of CO2.

Alex R. Sapre; John R. Hummel; Ruth A. Reck

1982-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "organisms synthetic biology" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


201

1 Synthetic Texturing 1.1 Introduction  

E-Print Network (OSTI)

1 Synthetic Texturing 1.1 Introduction This dissertation describes improved methods for computer of this, the top of Figure 1.1 shows a horse model with a white surface and the bottom shows this same-hocformulasforlightreflection Figure 1.1: Stripe texture created using reaction-diffusion. Top is an untextured horse and the bottom

Turk, Greg

202

Biological Evaluation  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Biological Evaluation Biological Evaluation for the Proposed United States Army Military Training Activities on the Savannah River Site Department of the Army - Fort Gordon Range Control - Directorate of Plans, Training, Mobilization, and Security Location: Aiken, Allendale, and Barnwell Counties, SC., Savannah River Site Contact Person: Donald S. McLean, 706-840-5522 / 706-791-2422 Submitted by Fort Gordon Range Control Training Facility Coordinator (DPTMS) Prepared By: ___________________________________________________________________ Donald S. McLean, Training Facility Coordinator Fort Gordon Georgia Date: 2 Table of Contents Summary, Page 4 Introduction, Page 6 Project Description, Page 6 Purpose and Need for Proposed Action, Page 7

203

Structural Biology | Biosciences Division  

NLE Websites -- All DOE Office Websites (Extended Search)

Membrane Protein Membrane Protein Expression System BIO Home Page About BIO News Releases Research Publications People Contact Us Organization Chart Site Index Inside BIO BIO Safety About Argonne Membrane Protein Engineering Membrane protein expression system The cell membrane serves as the interface between an organism and its environment, and internal membranes in eukaryotes separate functional compartments within cells. Proteins inserted in these membranes carry out many essential biological processes including uptake of nutrients, excretion of wastes, signal transduction, and response to external stimuli. In addition, membrane proteins are used in elaborate bioenergetic schemes to fuel all normal cellular activities in healthy organisms. In this post-genomic era, about 35% of the genes in any genome encode membrane proteins. The fraction of proteins associated with the membrane in eukaryotes may be even higher (up to 40%). Notably, membrane proteins constitute the majority of drug targets, thus knowledge of the structures of these proteins would contribute greatly to our understanding of biological processes. Unfortunately, structural information for membrane proteins is exceedingly scarce. It is notoriously difficult to purify quantities of native material that are sufficient for crystallization attempts. As a result, to date, the three-dimensional structures of ~60 unique transmembrane proteins are known in comparison to the structures of representatives of more than ~4000 soluble protein families.

204

Biological clock  

NLE Websites -- All DOE Office Websites (Extended Search)

Biological clock Biological clock Name: N/A Location: N/A Country: N/A Date: N/A Question: How does a person's biological clock work? Replies: I believe there's a region or gland in the brain that regulates biological clocks. This region or gland senses the environment's day/night cycle. I'm afraid I don't know much more than that. Hope this helps. --- jade No one knows for sure how any circadian (nearly 24 hour-in Latin) clock works. Some interesting facts, though. The pineal gland in the brain is important. Although shifting the day-night cycle can shift the clock, the clock runs on its own without any dark-light cues. So it seems to be a natural chemical clock with a cycle nearly, but not exactly at 24 hours, which is entrained by the 24 hour day-night cycle. There are neurons in lower animals which can be kept alive alone, isolate from the nervous system and from any light-dark cues, that show electrical activity on a near-24-hours cycle

205

Development of Standards for NanoSIMS Analyses of Biological Materials  

SciTech Connect

NanoSIMS is a powerful analytical technique for investigating element distributions at the nanometer scale, but quantifying elemental abundances requires appropriate standards, which are not readily available for biological materials. Standards for trace element analyses have been extensively developed for secondary ion mass spectrometry (SIMS) in the semiconductor industry and in the geological sciences. The three primary approaches for generating standards for SIMS are: (1) ion implantation (2) using previously characterized natural materials, and (3) preparing synthetic substances. Ion implantation is a reliable method for generating trace element standards, but it is expensive, which limits investigation of the analytical issues discussed above. It also requires low background levels of the elements of interest. Finding or making standard materials has the potential to provide more flexibility than ion implantation, but realizing homogeneity at the nano-scale is in itself a significant challenge. In this study, we experiment with all three approaches, but with an emphasis toward synthetic organic polymers in order to reduce costs, increase flexibility, and achieve a wide dynamic concentration range. This emphasis serves to meet the major challenge for biological samples of identifying matrix matched, homogeneous material. Biological samples themselves are typically heterogeneous at the scale of microns to 100s of microns, and therefore they are poor SIMS standards. Therefore, we focused on identifying 'biological-like' materials--either natural or synthetic--that can be used for standards. The primary criterion is that the material be as compositionally similar to biological samples as possible (primarily C, H, O, and N). For natural material we adsorbed organic colloids consisting of peptidoglycan (i.e., amino sugars), activated charcoal, and humic acids. Experiments conducted with Si on peptidoglycan showed low affinity as SiO{sub 2}, yet its distribution in the matrix was similar to that observed in spores. In experiments with Mo on humic acid, homogeneity was achieved and a sensitivity factor relative to C was determined. For synthetic material, we successfully prepared polyacrylic acid containing complexed elements of Mo, Ca, Sr, and Ba at low abundance. These were prepared as aqueous mixtures of dissolved elements and polyacrylic resin, followed by thin film drying. The Mo was homogeneously distributed and yielded a relative sensitivity factor nearly identical to that calculated for humic acid. This approach shows great promise for most water soluble metals. Poly(methacrylate) thin films were prepared that contained different low-level concentrations of Si introduced as a silane compound. Although homogeneity was not fully achieved, the analytical results did validate our previous quantitative methodology for Si. In addition, Commercial plastics were also examined for suitability for F and Cl. We found food-grade polyvinyl tubing produced high precision Cl determinations. For ion implantation, we used epoxy as the substrate and successfully extracted depth profiles and sensitivity factors for F and Cu.

Davission, M L; Weber, P K; Pett-Ridge, J; Singer, S

2008-07-31T23:59:59.000Z

206

MST: Organizations: Organic Materials  

NLE Websites -- All DOE Office Websites (Extended Search)

Adhesive Bonding Adhesive Bonding Composites Encapsulation Materials Characterization Mechanical Testing Molding, Thermoforming, & Compounding Organizations Organic Materials Composite-to-metal adhesive bond Experimental/analytical study of composit-to-metal adhesive bond. The Organic Materials department in the Advanced Manufacturing and Processing Laboratory provides innovative prototype fabrication, full service small lot production, materials technology, processing expertise, and a broad range of organic material characterization and mechanical testing techniques. We encapsulate, we join and bond, we foam, we analyze and image, we build composite structures. We strive to make you, our customers, successful! We partner with you to find the right combination of materials, processing, and fixturing that will result in the highest value

207

Organic Vegetable Organic Vegetable  

E-Print Network (OSTI)

marketed separately from conventionally grown produce in order to be profitably sold. Because of the amount of organic material include compost, Purdue University · Cooperative Extension Service · Knowledge to Go

208

Feedback control of flow separation using synthetic jets  

E-Print Network (OSTI)

The primary goal of this research is to assess the effect of synthetic jets on flow separation and provide a feedback control strategy for flow separation using synthetic jets. The feedback control synthesis is conducted based upon CFD simulation...

Kim, Kihwan

2006-04-12T23:59:59.000Z

209

Regulation of Gene Expression by Synthetic DNA-Binding Ligands  

E-Print Network (OSTI)

Regulation of Gene Expression by Synthetic DNA-Binding Ligands Peter B. Dervan ( ) · Adam T. Poulin

Dervan, Peter B.

210

Synthetic logs generator for fraud detection in mobile transfer services  

E-Print Network (OSTI)

Synthetic logs generator for fraud detection in mobile transfer services C. Gaber12 , B. Hemery2.gaber,mohammed.achemlal}@orange.com Abstract. This article presents a simulator which generates synthetic data for fraud detection. It models fraudsters and legitimate users. Keywords: synthetic data, simulation, fraud detection Mobile payments become

Boyer, Edmond

211

Department of Mechanical Engineering Spring 2012 Synthetic Cable Termination  

E-Print Network (OSTI)

PENNSTATE Department of Mechanical Engineering Spring 2012 Synthetic Cable Termination Overview NAVAIR is attempting to replace their existing metallic purchase cable with a new, synthetic cable. The synthetic cable is currently not able to be tensile tested because there is no way for the ends

Demirel, Melik C.

212

Biological Safety Cabinets n Product protection  

E-Print Network (OSTI)

2.7 #12;Biological Safety Cabinets Purpose n Product protection n Personal protection n Environmental protection 2.7 #12;Biological Safety Cabinets Types A. Class I n inward airflow protects worker n" work area n use for work with aerosol-transmissible micro- organisms n use also for tissue culture

Collins, Gary S.

213

Grasshopper Biology  

NLE Websites -- All DOE Office Websites (Extended Search)

Grasshopper Biology Grasshopper Biology Name: s. Location: N/A Country: N/A Date: N/A Question: My son found a grasshopper and put it in a fish bowl with cover, and we need to know what to feed it? we have it some lettuce and apple and a bit of water. Replies: Sounds ok so far, most any kind of green plant should be ok, doubt it will pay too much attention to the water. Don't expect it to live very long though. J. Elliott Hello, Grasshoppers eat green vegetation of various kinds. They especially love tall grass. The greener the better. Clip a variety of plants from a nearby unmowed ditch or vacant lot and place them in a short container of water and place the container of water and plants in your fish bowl. The grasshopper will "eat it up". Wayne Vanderploeg River Trail Nature Center

214

Production of biocommodities and bioelectricity by cell-free synthetic enzymatic pathway biotransformations: Challenges and opportunities  

NLE Websites -- All DOE Office Websites (Extended Search)

PERSPECTIVE PERSPECTIVE Production of Biocommodities and Bioelectricity by Cell-Free Synthetic Enzymatic Pathway Biotransformations: Challenges and Opportunities Y.-H. Percival Zhang 1,2,3 1 Biological Systems Engineering Department, Virginia Polytechnic Institute and State University, 210-A Seitz Hall, Blacksburg, Virginia 24061; telephone: 540-231-7414; fax: 540-231-3199; e-mail: biofuels@vt.edu 2 Institute for Critical Technology and Applied Science (ICTAS), Virginia Polytechnic Institute and State University, Blacksburg, Virginia 3 DOE Bioenergy Science Center, Oak Ridge, Tennessee Received 21 July 2009; revision received 18 November 2009; accepted 23 November 2009 Published online 7 December 2009 in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/bit.22630 ABSTRACT: Cell-free synthetic (enzymatic) pathway bio- transformation (SyPaB)

215

Biological stability of groundwater  

SciTech Connect

Conventional (e.g., coagulation, flocculation, and filtration) or membrane filtration treatment trains were used to remove organic compounds from groundwater. For the conventional train with sand-anthracite columns, the assimilable organic carbon (AOC) of the groundwater was reduced from 349 {+-} 127 {micro}g/L C to 54 {+-} 51 {micro}g/L C. For the membrane filtration train, there was no statistical difference between the AOC of the raw water influent (388 {+-} 126 {micro}g C) and that of the membrane permeate (334 {+-} 156 {micro}g/L C), suggesting that this treatment produced biologically unstable water. Similar results were obtained using the heterotrophic growth response (HGR) method. Comparison of the biostability methods showed that HGR was positively correlated with AOC (r = 0.52; P < 0.0001; n = 156), indicating that AOC only partially explains the ability of heterotrophic bacteria to grow in water samples.

Noble, P.A. [Univ. of Maryland Biotechnology Inst., Baltimore, MD (United States). Center of Marine Biotechnology; Clark, D.L. [Irvine Ranch Water District, CA (United States); Olson, B.H. [Univ. of California, Irvine, CA (United States). School of Social Ecology, Environmental Analysis, and Design

1996-05-01T23:59:59.000Z

216

Synthetic and Biosynthetic Studies of Natural Products  

E-Print Network (OSTI)

of the Scholarly Communications program at the University of Kansas Libraries’ Center for Digital Scholarship. http://kuscholarworks.ku.edu B Y E. IfEJ.32 S Synthetic and Biosynthetic Studies of Natural Products Part I. Studies Directed Toward the Total Synthesis... of 4-Demethoxy -A-Homodaunorubicin Analogs Part II. Biosynthesis of Coloradocin. Origin of the Carbons Part III. Total Synthesis of the Naturally Occurring Prenylated Bibenzyl Amorfrutin A Eduardo Alberto Veliz Chanis B.S., University of Panama...

Ve?liz Chanis, Eduardo Alberto

1992-05-01T23:59:59.000Z

217

“Invisible” Synthetic Opiates and Acute Psychosis  

Science Journals Connector (OSTI)

...revisiting. Another striking fact is that nalbuphine may interfere with enzymatic methods for the detection of specific opiates, and it is virtually invisible to routine toxicologic tests,, as in the case we report. When there is suspicion of nalbuphine intoxication, routine screening for opiates should... To the Editor: Many acute psychotic episodes encountered in emergency situations are related to addictive substances. Nalbuphine is a synthetic opiate agonist–antagonist, chemically related to both the opioid antagonist naloxone and the analgesic ...

2001-08-09T23:59:59.000Z

218

Carboxylic acid sorption on synthetic clays in marine water: in vitro experiments and implications for organo-clay behaviour under marine conditions  

E-Print Network (OSTI)

1 Carboxylic acid sorption on synthetic clays in marine water: in vitro experiments-clay association indicates that, under marine water column conditions, the organic fixation is only a sorption organic carbon m-2 ), demonstrates that the sorption is controlled by the surface properties of clays

219

E-Print Network 3.0 - acoustics synthetic aperture Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

Synthetic aperture focusing... Introduction Synthetic aperture focusing techniques (SAFT) ... Source: Uppsala Universitet, Department of Material Science, Signals and Systems...

220

The Biology of You  

E-Print Network (OSTI)

Merced majoring in Human Biology with a minor in Creativeschool in the future. the biology of you 137 UC Merced

Inneh, Joy

2013-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "organisms synthetic biology" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


221

Biological Science  

NLE Websites -- All DOE Office Websites (Extended Search)

Biological Science Biological Science A unique zinc-binding site revealed by the high-resolution x-ray structure of homotrimeric Apo2L/TRAIL S.G. Hymowitz, M.P. O'Connell, M.H. Ultsch, A. Hurst, K. Totpal, A. Ashkenazi, R.F. Kelley, and A.M. de Vos b-carbonic anhydrase active site architecture is a mirror image of a-carbonic anhydrases E.F. Pai and M.S. Kimber Binding of Cd ions to the cell wall of B. Subtilis - an EXAFS study M. Boyanov, D. Fowle, K. Kemner, B. Bunker, and J. Fein Crystallographic evidence for Try157 functioning as the active site base in human UDP-galactose 4-epimerase J.B. Thoden, T.M. Wohlers, J.L. Fridovich-Keil, and H.M. Holden Crystallographic studies of dsDNA phage HK97 structure and maturation W.R. Wikoff, Z. Che, W. Schildkamp, L. Liljas, R.L. Duda, R.W. Hendrix, and

222

Chemical Biology DOI: 10.1002/anie.201005461  

E-Print Network (OSTI)

as a Platform for Integrating Chemical and Biological Research S. Elizabeth Hulme and George M. WhitesidesChemical Biology DOI: 10.1002/anie.201005461 Chemistry and the Worm: Caenorhabditis elegans* Angewandte Chemie Keywords: biochemistry · Caenorhabditis elegans · chemical biology · model organisms

Church, George M.

223

Hindawi Publishing Corporation EURASIP Journal on Bioinformatics and Systems Biology  

E-Print Network (OSTI)

--from a system's biological point of view--could be understood as organized in interacting networks at allHindawi Publishing Corporation EURASIP Journal on Bioinformatics and Systems Biology Volume 2009 and Biometry, Research Institute for the Biology of Farm Animals (FBN), Wilhelm-Stahl Allee 2, D 18196

224

Science Organizations  

NLE Websites -- All DOE Office Websites (Extended Search)

Organizations Science Organizations National security depends on science and technology. The United States relies on Los Alamos National Laboratory for the best of both. No place...

225

Chemistry in Motion: Tiny Synthetic Motors  

E-Print Network (OSTI)

In this Account, we describe how synthetic motors that operate by self-diffusiophoresis make use of a self-generated concentration gradient to drive motor motion. A description of propulsion by self-diffusiophoresis is presented for Janus particle motors comprising catalytic and noncatalytic faces. The properties of the dynamics of chemically powered motors are illustrated by presenting the results of particle-based simulations of sphere-dimer motors constructed from linked catalytic and noncatalytic spheres. The geometries of both Janus and sphere-dimer motors with asymmetric catalytic activity support the formation of concentration gradients around the motors. Because directed motion can occur only when the system is not in equilibrium, the nature of the environment and the role it plays in motor dynamics are described. Rotational Brownian motion also acts to limit directed motion, and it has especially strong effects for very small motors. We address the following question: how small can motors be and still exhibit effects due to propulsion, even if only to enhance diffusion? Synthetic motors have the potential to transform the manner in which chemical dynamical processes are carried out for a wide range of applications.

Peter H. Colberg; Shang Yik Reigh; Bryan Robertson; Raymond Kapral

2014-11-03T23:59:59.000Z

226

Synthetic Aperture Radar Persistent Scatterer Interferometry (PSInSAR) |  

Open Energy Info (EERE)

Synthetic Aperture Radar Persistent Scatterer Interferometry (PSInSAR) Synthetic Aperture Radar Persistent Scatterer Interferometry (PSInSAR) Jump to: navigation, search OpenEI Reference LibraryAdd to library Web Site: Synthetic Aperture Radar Persistent Scatterer Interferometry (PSInSAR) Author Parviz Tarikhi Published N/A, 2010 DOI Not Provided Check for DOI availability: http://crossref.org Online Internet link for Synthetic Aperture Radar Persistent Scatterer Interferometry (PSInSAR) Citation Parviz Tarikhi. Synthetic Aperture Radar Persistent Scatterer Interferometry (PSInSAR) [Internet]. 2010. Tunis, Tunisia. N/A. [cited 2013/09/17]. Available from: http://parviztarikhi.files.wordpress.com/2010/05/3psinsar-i-parviz_tarikhi.pdf Retrieved from "http://en.openei.org/w/index.php?title=Synthetic_Aperture_Radar_Persistent_Scatterer_Interferometry_(PSInSAR)&oldid=682949"

227

On Biology as an Emergent Science  

E-Print Network (OSTI)

Biology is considered here as an "emergent science" in the sense of Anderson and of Laughlin and Pines. It is demonstrated that a straightforward mathematical definition of "biological system" is useful in showing how biology differs in structure from the lower levels in Anderson's "More is Different" hierarchy. Using cells in a chemostat as a paradigmatic exemplar of a biological system, it is found that a coherent collection of metabolic pathways through a single cell in the chemostat also satisfies the proposed definition of a biological system. This provides a theoretical and mathematical underpinning for Young's fundamental model of biological organization and integration. Evidence for the therapeutic efficacy of Young's method of analysis is provided by preliminary results of clinical trials of a specific application of Young's model to the treatment of cancer cachexia.

H. Pierre Noyes

2007-05-31T23:59:59.000Z

228

Spectral Study of DNA Adsorption on Natural and Synthetic Silicates  

Science Journals Connector (OSTI)

Adsorption and interaction capacity of DNA with three types of natural silicates (chrysotile, crocidolite, clinoptilolite) and one synthetic Y zeolite were studied. The influence of ... pretreatment of silicates ...

R. Stanescu-Dumitru; C. Mandravel…

1997-01-01T23:59:59.000Z

229

Synthetic nanotubes lay foundation for new technology: Artificial...  

NLE Websites -- All DOE Office Websites (Extended Search)

Synthetic nanotubes lay foundation for new technology: Artificial pores mimic key features of natural pores By Tona Kunz * July 17, 2012 Tweet EmailPrint Scientists have overcome...

230

US Synthetic Corp (TRL 4 Component) - The Development of Open...  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Polycrystalline Diamond Thrust Bearings for use in Marine Hydrokinetic (MHK) Energy Machines US Synthetic Corp (TRL 4 Component) - The Development of Open, Water Lubricated...

231

Intramolecular hydrogen bonding as a synthetic tool to induce...  

NLE Websites -- All DOE Office Websites (Extended Search)

Intramolecular hydrogen bonding as a synthetic tool to induce chemical selectivity in acid catalyzed porphyrin synthesis Authors: Megiatto, J. D., Patterson, D., Sherman, B. D.,...

232

Vehicle Technologies Office Merit Review 2014: Synthetic Solutions...  

Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

about synthetic solutions for correcting voltage fade in LMR-NMC cathodes. es190johnson2014o.pdf More Documents & Publications Cathode Synthesis and Voltage Fade: Designed...

233

The Entire Molecular Biology Archive  

NLE Websites -- All DOE Office Websites (Extended Search)

Molecular Biology Archives Molecular Biology Archives Molecular Biology, Since May 2000 Table of Contents: Blood pH and Oxygen DNA Extraction Flesh Eating Bacteria Amino Acid Differences Lyme Disease Effects Vinegar and Alcohol Mosquito and Blood Caffeine and Smoking Bread Mold and pH Hemocyanin and Hemerythrin Hodospin Man-made Bacteria Pregnancy Tips mRNA Killing Bacteria Gram Stain Milk Bacteria Denatured Protein Pseudmands Bacteria Nucleotide Order Bacteria Resistance Albinism Genes DNA Healing Re-constitution of Proteins H. pylori and Multiple sclerosis Smallest Organism Sugars and Fats Bacteria Systematics Slow Regeneration Media Cultures Butter and Bacteria AIDS and Survival in Air Cell Intelligence Giardia gingivalis Meat Bacteria Pus and Immune Cells Chalones Culture of T. ferrooxisans Amphibian E. coli

234

Organization | Department of Energy  

Energy Savers (EERE)

About Us Organization Organization Organization Printable PDF News & Blog CIO Leadership Organization Contact Us...

235

Organization | Department of Energy  

Office of Environmental Management (EM)

About Us Organization Organization Organization News Leadership Organization History Careers Contact Us...

236

Environmental Biology | Biosciences Division  

NLE Websites -- All DOE Office Websites (Extended Search)

Sustainable Bioenergy Crop Production Research Sustainable Bioenergy Crop Production Research Facility BIO Home Page About BIO News Releases Research Publications People Contact Us Organization Chart Site Index Inside BIO BIO Safety About Argonne Sustainable Bioenergy Crop Production Research Facility R. Michael Miller, Argonne contact (rmmiller@anl.gov) The overall goal of our field research facility is to identify plant and microbial processes that will be key contributors to sustainable low-input (fertilizer) bioenergy feedstock production and, at the same time, will enhance the capture and storage of greenhouse gases by plants and soils (biological carbon sequestration). A unique feature of our native perennial bioenergy research facility is a gradient of biodiversity -- both within and between species diversity. Although a number of long-term ecological studies have demonstrated benefits to biomass production and carbon sequestration from increased species richness, none have investigated whether within-species diversity (i.e., genetic diversity) can contribute similar improvements.

237

Plant Vascular Biology 2010  

SciTech Connect

This grant supported the Second International Conference on Plant Vascular Biology (PVB 2010) held July 24-28, 2010 on the campus of Ohio State University, Columbus, Ohio. Biao Ding (Ohio State University; OSU) and David Hannapel (Iowa State University; ISU) served as co-chairs of this conference. Biao Ding served as the local organizer. PVB is defined broadly here to include studies on the biogenesis, structure and function of transport systems in plants, under conditions of normal plant growth and development as well as of plant interactions with pathogens. The transport systems cover broadly the xylem, phloem, plasmodesmata and vascular cell membranes. The PVB concept has emerged in recent years to emphasize the integrative nature of the transport systems and approaches to investigate them.

Ding, Biao

2014-11-17T23:59:59.000Z

238

Synthetic DNA minor groove-binding drugs  

Science Journals Connector (OSTI)

In this review, both cationic and neutral synthetic ligands that bind in the minor groove of DNA are discussed. Certain bis-distamycins and related lexitropsins show activities against human immunodeficiency virus (HIV)-1 and HIV-2 at low nanomolar concentrations. DAPI binds strongly to AT-containing polymers and is located in the minor groove of DNA. DAPI intercalates in DNA sequences that do not contain at least three consecutive AT bp. Berenil can also exhibit intercalative, as well as minor groove binding, properties depending on sequence. Furan-containing analogues of berenil play an important role in their activities against Pneumocystis carinii and Cryptosporidium parvuam infections in vivo. Pt(II)-berenil conjugates show a good activity profile against HL60 and U-937 human leukemic cells. Pt-pentamidine shows higher antiproliferative activity against small cell lung, non-small cell lung, and melanoma cancer cell lines compared with many other tumor cell lines. trans-Butenamidine shows good anti-P. carinii activity in rats. Pentamidine is used against P. carinii pneumonia in individuals infected with HIV who are at high risk from this infection. A comparison of the cytotoxic potencies of adozelesin, bizelesin, carzelesin, cisplatin, and doxorubicin indicates that adozelesin is a potent analog of CC-1065. Naturally occurring pyrrolo[2,1-c][1,4]benzodiazepines such as anthramycin have a 2- to 3-bp sequence specificity, but a synthetic PBD dimer spans 6 bp, actively recognizing a central 5?-GATC sequence. The crosslinking efficiency of PBD dimers is much greater than that of other major groove crosslinkers, such as cisplatin, melphalan, etc. Neothramycin is used clinically for the treatment of superficial carcinoma of the bladder.

B.S.Praveen Reddy; S.Murari Sondhi; J.William Lown

1999-01-01T23:59:59.000Z

239

Supporting Information for: Synthetic Control of Green Fluorescent Protein (GFP)  

E-Print Network (OSTI)

, and then using DNA ligase to insert synthetic oligonucleotides containing the loop sequence were inserted usingS1 Supporting Information for: Synthetic Control of Green Fluorescent Protein (GFP) Kevin P. Kent the genes in pET-15b with restriction enzymes that cut the DNA close to the desired loop insertion site

Boxer, Steven G.

240

1 - Gasification and synthetic liquid fuel production: an overview  

Science Journals Connector (OSTI)

Abstract This chapter discusses general considerations on gasification processes and synthetic liquid fuel production. It provides an overview of state-of-the-art gasification technologies, feedstocks and applications in power generation, and synthetic fuels production, together with some recent future trends in the field.

R. Luque; J.G. Speight

2015-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "organisms synthetic biology" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


241

Synthetic logs generator for fraud detection in mobile transfer services  

E-Print Network (OSTI)

Synthetic logs generator for fraud detection in mobile transfer services Chrystel Gaber, Baptiste to commit crimes and avoid detection, research in the field of fraud is always evolving. However, trans synthetic logs with real ones. I. INTRODUCTION Frauds in the field of electronic payment evolve contin

Paris-Sud XI, Université de

242

Operation Allelopathy: An Experiment Investigating an Alternative to Synthetic Agrochemicals  

Science Journals Connector (OSTI)

Operation Allelopathy: An Experiment Investigating an Alternative to Synthetic Agrochemicals ... The experiment involves an evaluation by students of the potential of plant extracts as an alternative to synthetic agrochemicals to identify new ecological farming techniques that could be applied in agriculture. ... Instead, natural products constitute an attractive source of agrochemicals with great potential. ...

Nuria Chinchilla; Alexandra G. Durán; Ceferino Carrera; Jesús Ayuso; Francisco A. Macías

2013-11-22T23:59:59.000Z

243

Cation exchange at the secondary building units of metal–organic frameworks  

E-Print Network (OSTI)

Cation exchange is an emerging synthetic route for modifying the secondary building units (SBUs) of metal–organic frameworks (MOFs). This technique has been used extensively to enhance the properties of nanocrystals and ...

Brozek, Carl Kavanaugh

244

Inversion of synthetic aperture radar interferograms for sources of  

Open Energy Info (EERE)

Inversion of synthetic aperture radar interferograms for sources of Inversion of synthetic aperture radar interferograms for sources of production-related subsidence at the Dixie Valley geothermal field Jump to: navigation, search OpenEI Reference LibraryAdd to library Journal Article: Inversion of synthetic aperture radar interferograms for sources of production-related subsidence at the Dixie Valley geothermal field Authors Bill Foxall and D. W. Vasco Published Journal Journal of Volcanology and Geothermal Research, 2008 DOI Not Provided Check for DOI availability: http://crossref.org Online Internet link for Inversion of synthetic aperture radar interferograms for sources of production-related subsidence at the Dixie Valley geothermal field Citation Bill Foxall,D. W. Vasco. 2008. Inversion of synthetic aperture radar interferograms for sources of production-related subsidence at the Dixie

245

Synthetic Aperture Radar Movie Gallery -- Sandia National Laboratories  

NLE Websites -- All DOE Office Websites (Extended Search)

Synthetic Aperture Radar Movie Gallery Synthetic Aperture Radar Movie Gallery This gallery features movies of Sandia National Laboratories' synthetic aperture radar imagery of Albuquerque, New Mexico and Washington, DC. Sandia's Twin-Otter SAR produced these high-resolution stripmap images in real time. (Note: The movies below have been downsampled greatly to make them suitable for viewing on the world wide web. These movies are not recommended for modems of speeds less than 56 kbps due to their large file sizes.) Albuquerque, NM Area Movies Sandia National Laboratories' Twin-Otter SAR produced these Ku-Band 0.3 and 1.0 meter resolution images of Albuquerque, NM in real time. Synthetic aperture radar movie of west Gibson Blvd 0.3 meter airborne synthetic aperture radar movie from I-25 to Maxwell along Gibson Blvd. (Length: 30 seconds)

246

Chapter 14 - Phytoremediation of Pb-Contaminated Soils Using Synthetic Chelates  

Science Journals Connector (OSTI)

Abstract Although industrialization and high input agriculture has led to improvements in standards of human life on earth, it has resulted in multifarious problems for all inhabitants of this blue planet. Among many others, enrichment of water–soil–plant ecosystem with potentially toxic elements is considered to be one of the most serious threats due to ill effects over all living organisms including humans. As compared to other toxic elements, soil contamination due to Pb warrants special attention because of its long retention in soil and lethal effects on crop growth and human health. A number of techniques have been developed and devised to lower the total and / or available Pb concentration in soils and in turn their accumulation the food chain. However, phytoextraction has attracted tremendous attention from the scientific community due to its lower cost, less disruptive effects on soil and the surrounding environment, and wider acceptance in society. The total concentration of Pb in contaminated soils may not be truly representative of its bioavailability because the major portions of Pb in soil occur in the unavailable forms. Therefore, certain types of chemicals are applied to soil to increase the mobility and phytoavailabilty of Pb to help improve phytoremediative ability of plants to clean up soil within a reasonable time frame. Synthetic and natural organic ligands, such as EDTA, ethylene diamine disuccinate (EDDS), low-molecular-weight organic acids (LMWOA), nitrilotriacetic acid (NTA) and humic substances (HSs) have been used extensively in Pb remediation techniques. With increasing use of synthetic chelants for remediation techniques, detailed understanding of key factors and mechanisms behind this technology is needed before its application on a commercial basis. The present manuscript, therefore, highlights the role of synthetic chelators in the remediation of Pb contaminated soils and also critically assesses the risks and limitations associated with this technology.

Saifullah; Muhammad Shahid; Muhammad Zia-Ur-Rehman; Muhammad Sabir; Hamaad Raza Ahmad

2015-01-01T23:59:59.000Z

247

A threshold area ratio of organic to conventional agriculture causes recurrent pathogen outbreaks in organic agriculture  

E-Print Network (OSTI)

A threshold area ratio of organic to conventional agriculture causes recurrent pathogen outbreaks in organic agriculture S. Adl a, , D. Iron b , T. Kolokolnikov b a Department of Biology, Dalhousie Fungal spores Organic agriculture Pathogen dispersal Conventional agriculture uses herbicides, pesticides

Kolokolnikov, Theodore

248

A Synthetic Resilin Is Largely Unstructured  

SciTech Connect

Proresilin is the precursor protein for resilin, an extremely elastic, hydrated, cross-linked insoluble protein found in insects. We investigated the secondary-structure distribution in solution of a synthetic proresilin (AN16), based on 16 units of the consensus proresilin repeat from Anopheles gambiae. Raman spectroscopy was used to verify that the secondary-structure distributions in cross-linked AN16 resilin and in AN16 proresilin are similar, and hence that solution techniques (such as NMR and circular dichroism) may be used to gain information about the structure of the cross-linked solid. The synthetic proresilin AN16 is an intrinsically unstructured protein, displaying under native conditions many of the characteristics normally observed in denatured proteins. There are no apparent {alpha}-helical or {beta}-sheet features in the NMR spectra, and the majority of backbone protons and carbons exhibit chemical shifts characteristic of random-coil configurations. Relatively few peaks are observed in the nuclear Overhauser effect spectra, indicating that overall the protein is dynamic and unstructured. The radius of gyration of AN16 corresponds to the value expected for a denatured protein of similar chain length. This high degree of disorder is also consistent with observed circular dichroism and Raman spectra. The temperature dependences of the NH proton chemical shifts were also measured. Most values were indicative of protons exposed to water, although smaller dependences were observed for glycine and alanine within the Tyr-Gly-Ala-Pro sequence conserved in all resilins found to date, which is the site of dityrosine cross-link formation. This result implies that these residues are involved in hydrogen bonds, possibly to enable efficient self-association and subsequent cross-linking. The {beta}-spiral model for elastic proteins, where the protein is itself shaped like a spring, is not supported by the results for AN16. Both the random-network elastomer model and the sliding {beta}-turn model are consistent with the data. The results indicate a flat energy landscape for AN16, with very little energy required to switch between conformations. This ease of switching is likely to lead to the extremely low energy loss on deformation of resilin.

Nairn, Kate M.; Lyons, Russell E.; Mulder, Roger J.; Mudie, Stephen T.; Cookson, David J.; Lesieur, Emmanuelle; Kim, Misook; Lau, Deborah; Scholes, Fiona H.; Elvin, Christopher M. (CSIRO/MSE); (CSIRO/MHT); (CSIRO/LI); (Aust. Synch.)

2008-11-03T23:59:59.000Z

249

BS in BIOPHYSICS (285720) MAP Sheet Department of Physiology and Developmental Biology  

E-Print Network (OSTI)

351 Organic Chemistry Chem 352 Organic Chemistry Chem 353 Organic Chemistry Lab-Nonmajor (1 hour Foundation Book of Mormon New Testament Doctrine and Covenants The Individual and Society Citizenship of Biology PDBio 360 Cell Biology PWS 340 Genetics Complete the following chemistry courses: Chem 105

Olsen Jr., Dan R.

250

Quantitative study of Helicobacter pylori in gastric mucus by competitive PCR using synthetic DNA fragments.  

Science Journals Connector (OSTI)

...mucus by competitive PCR using synthetic DNA fragments T Furuta E Kaneko M...method using various amounts of synthetic DNA fragments containing the same...mucus by competitive PCR using synthetic DNA fragments. | Helicobacter pylori...

T Furuta; E Kaneko; M Suzuki; H Arai; H Futami

1996-10-01T23:59:59.000Z

251

Synthetic DNA probes for detection of enterotoxigenic Clostridium perfringens strains isolated from outbreaks of food poisoning.  

Science Journals Connector (OSTI)

...research-article Research Article Synthetic DNA probes for detection of enterotoxigenic...potential to produce enterotoxin. Synthetic DNA probes for detection of enterotoxigenic...American Society for Microbiology Synthetic DNA Probes for Detection of Enterotoxigenic...

M Van Damme-Jongsten; J Rodhouse; R J Gilbert; S Notermans

1990-01-01T23:59:59.000Z

252

Fewer invited talks by women in evolutionary biology symposia J. SCHROEDER1 , 2  

E-Print Network (OSTI)

for Ornithology, Seewiesen, Germany; 3 Behavioural Ecology and Self-Organization, University of Groningen, Groningen, The Netherlands; 4 Theoretical Biology, University of Groningen, Groningen, The Netherlands; 5 Ecology, University of Groningen, Groningen, The Netherlands; 16 Department of Biology, Evolutionary

West, Stuart

253

Protein folding and misfolding: a paradigm of self–assembly and regulation in complex biological systems  

Science Journals Connector (OSTI)

...self-assembly, for instance in nanotechnology. More fundamentally, we...self-assembly, for instance in nanotechnology. More fundamentally, we...self-organization; nanotechnology; biological evolution One...biology, physiology and medicine. No individual level of...

2003-01-01T23:59:59.000Z

254

DNA adsorption on synthetic and natural allophanes  

Science Journals Connector (OSTI)

The adsorption of DNA on natural and synthetic samples of allophane, which is a primary clay mineral of andosols, was investigated with respect to the DNA concentration, pH, ionic strength in the sample solution, and competition between DNA molecules and phosphate ions for adsorption to understand the behavior of extracellular DNA molecules in andosols. The relationships between DNA adsorption and the final concentrations were significantly fitted to a simple linear Langmuir equation. DNA adsorption decreased considerably with increasing suspension pH in the range between 3 and 9. The adsorption was less affected by the ionic strength of the suspension from 0.1 to 0.5 mol L? 1. Under the same experimental conditions, DNA adsorption on allophanes was relatively higher than that on montmorillonite and silica but relatively lower than that on gibbsite and goethite. DNA adsorption on allophanes decreased on the addition of phosphate, indicating that there was a competition between DNA molecules and phosphate ions for adsorption on the minerals. These results suggested that DNA adsorption on allophanes occurred via two mechanisms: direct bonding of the phosphate group at the end of the DNA molecule to the OH groups of the Al-oxide layer on allophane, and the association of DNA molecules with the surface of negatively charged allophane via a bridging of inorganic cations.

Kazutoshi Saeki; Masao Sakai; Shin-Ichiro Wada

2010-01-01T23:59:59.000Z

255

Naphthenic acid corrosion in synthetic fuels production  

SciTech Connect

Serious corrosion damage to carbon steel piping in a fractionation unit associated with synthetic fuels production has been ascribed to the presence of naphthenic acids. Investigation of the problem revealed total acids numbers (TAN) ranging from 8--12mg KOH/g in the feed to the unit. Damage typically occurred in the temperature range 180--240 C and manifested as localized pitting, preferential weld corrosion, general wall thinning and end-grain attack. Filming amine corrosion inhibitors designed for refinery overhead systems have been proven ineffective and high temperature phosphate-based inhibitors could not be used due to potential catalyst poisoning in downstream refinery units. Coupon exposures indicated corrosion rates in the order of 2 mm/y on carbon steel in a reboiler line as well as pitting to austenitic stainless steel type UNS S30403. Line replacement in austenitic stainless steel UNS S31603 has been proven effective. The performance of this alloy is mainly ascribed to its molybdenum content. The absence of sulfur in the feed to the unit is also contributing to the alloy performance despite the extremely high total acid numbers.

Bruyn, H.I. de [Mossgas Ltd., Mossel Bay (South Africa)

1998-12-31T23:59:59.000Z

256

Motion Measurement for Synthetic Aperture Radar.  

SciTech Connect

Synthetic Aperture Radar (SAR) measures radar soundings from a set of locations typically along the flight path of a radar platform vehicle. Optimal focusing requires precise knowledge of the sounding source locations in 3 - D space with respect to the target scene. Even data driven focusing techniques (i.e. autofocus) requires some degree of initial fidelity in the measurements of the motion of the radar. These requirements may be quite stringent especially for fine resolution, long ranges, and low velocities. The principal instrument for measuring motion is typically an Inertial Measurement Unit (IMU), but these instruments have inherent limi ted precision and accuracy. The question is %22How good does an IMU need to be for a SAR across its performance space?%22 This report analytically relates IMU specifications to parametric requirements for SAR. - 4 - Acknowledgements Th e preparation of this report is the result of a n unfunded research and development activity . Although this report is an independent effort, it draws heavily from limited - release documentation generated under a CRADA with General Atomics - Aeronautical System, Inc. (GA - ASI), and under the Joint DoD/DOE Munitions Program Memorandum of Understanding. Sandia National Laboratories is a multi - program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of En ergy's National Nuclear Security Administration under contract DE - AC04 - 94AL85000.

Doerry, Armin W.

2015-01-01T23:59:59.000Z

257

Synthetic aperture radar processing with tiered subapertures  

SciTech Connect

Synthetic Aperture Radar (SAR) is used to form images that are maps of radar reflectivity of some scene of interest, from range soundings taken over some spatial aperture. Additionally, the range soundings are typically synthesized from a sampled frequency aperture. Efficient processing of the collected data necessitates using efficient digital signal processing techniques such as vector multiplies and fast implementations of the Discrete Fourier Transform. Inherent in image formation algorithms that use these is a trade-off between the size of the scene that can be acceptably imaged, and the resolution with which the image can be made. These limits arise from migration errors and spatially variant phase errors, and different algorithms mitigate these to varying degrees. Two fairly successful algorithms for airborne SARs are Polar Format processing, and Overlapped Subaperture (OSA) processing. This report introduces and summarizes the analysis of generalized Tiered Subaperture (TSA) techniques that are a superset of both Polar Format processing and OSA processing. It is shown how tiers of subapertures in both azimuth and range can effectively mitigate both migration errors and spatially variant phase errors to allow virtually arbitrary scene sizes, even in a dynamic motion environment.

Doerry, A.W. [Sandia National Labs., Albuquerque, NM (United States). Synthetic Aperture Radar Dept.

1994-06-01T23:59:59.000Z

258

An assessment of the usefulness of 5 new synthetic pyrethroids in IPM programs for tobacco budworm control in cotton  

E-Print Network (OSTI)

New Synthetic Pyrethroids in IPM Programs for Tobacco Budworm Control in Cotton. (Mlay 1981) Sinnappu Victor Rajakulendran, B. Sc. (Agri. ) University of Sri Lanka Chairman of Advisory Committee: Dr. F. W. Plapp, Jr. Toxicity measurements were... of the synergist with any of the several processes that de- termine the ability of the insecticide to penetrate the organism and to be subsequently transported to the target site in concentrations sufficient to cause a toxic effect. However, most known cases...

Rajakulendran, Sinnappu Victor

2012-06-07T23:59:59.000Z

259

Applying Synthetic Lethality for the Selective Targeting of Cancer  

Science Journals Connector (OSTI)

...not yet been matched by progress in its clinical application. Nevertheless, synthetic lethality is a promising rationale that is ready for clinical testing. Time will tell how synthetic lethality will be integrated into therapeutic approaches. Synthetic lethality refers to the requirement that two defects be present for cell death to occur. When an agent damages DNA, its effects on the cell can be amplified if the efforts of the cell to repair the damage are inhibited. Clinical application of this idea is just beginning.

McLornan D.P.List A.Mufti G.J.

2014-10-30T23:59:59.000Z

260

Using synthetic biology to screen for functional diversity of GH1 enzymes  

SciTech Connect

Advances in next-generation sequencing technologies have enabled single genomes as well as complex environmental samples (metagenomes) to be comprehensively sequenced on a routine basis. Bioinformatics analysis of the resulting sequencing data reveals a continually expanding catalogue of predicted proteins ( 14 million as of April 2011), 75 percent of which are associated with functional annotation (COG, Pfam, Enzyme, Kegg, etc). These predicted proteins cover the full spectrum of known pathways and functional activities, including many novel biocatalysts that are expected to significantly contribute to the development of clean technologies including biomass degradation, lipid transformation for biodiesel generation, intermediates for polymer production, carbon capture, and bioremediation.

Deutsch, Sam; Datta, Supratim; Hamilton, Matthew; Friedland, Greg; D'Haeseleer, Patrik; Chen, Jan-Fang; Chivian, Dylan; Egan, Rob; Sale, Kenneth; Simmons, Blake; Rubin, Eddy

2011-05-31T23:59:59.000Z

Note: This page contains sample records for the topic "organisms synthetic biology" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


261

Flourishing and Discordance: On Two Modes of Human Science Engagement with Synthetic Biology  

E-Print Network (OSTI)

Charles Percy Snow delivered the Rede lecture, in Cambridge.98 The content of the Rede lecture Snow characterized asof the sciences. 101 In the Rede Lecture, Snow makes the

Stavrianakis, Anthony

2012-01-01T23:59:59.000Z

262

Foundation technologies in synthetic biology: tools for use in understanding plant immunity   

E-Print Network (OSTI)

The plant hormone salicylic acid (SA) is an essential activator of plant immune responses directed against biotrophic pathogens. The transcription cofactor NPR1 (Nonexpressor of pathogenesis- related (PR) genes 1) functions ...

Moore, John Wallace

2012-06-25T23:59:59.000Z

263

Synthetic Biology for Advanced Fuels (Opening Keynote Address - 2010 JGI User Meeting)  

ScienceCinema (OSTI)

Jay Keasling, CEO of the Joint BioEnergy Institute, delivers the opening keynote on March 24, 2010 at the 5th Annual DOE JGI User Meeting

Keasling, Jay

2011-04-28T23:59:59.000Z

264

Exploiting diversity and synthetic biology for the production of algal biofuels  

Science Journals Connector (OSTI)

... of Energy. Solazyme Integrated Biorefinery: Diesel fuels from heterotrophic algae. eere.energy.gov> (US Department of Energy, 2010).

D. Ryan Georgianna; Stephen P. Mayfield

2012-08-15T23:59:59.000Z

265

BglBrick vectors and datasheets; a synthetic biology platform for gene expression  

E-Print Network (OSTI)

the pSC101* origin were pSC101QC F1 and pSC101QC R1 creatingpSC101QC F1 5’- gaatttacagatacccagatcAcccgggaaaagg-3’ topSC101 pBBR1 F1 5’- gatcaCCTAGGctacagccgatagtctggaacagcgc -

2011-01-01T23:59:59.000Z

266

Flourishing and Discordance: On Two Modes of Human Science Engagement with Synthetic Biology  

E-Print Network (OSTI)

for the first time; the ETH-Zurich being the other one.Although part of the ETH Zurich, the D-BSSE is in Basel, abetween 2002 and 2003 ETH Zurich entered into negotiations

Stavrianakis, Anthony

2012-01-01T23:59:59.000Z

267

Computationally Optimised DNA Assembly of synthetic genes  

Science Journals Connector (OSTI)

Gene synthesis is hampered by two obstacles: improper assembly of oligonucleotides; oligonucleotide defects incurred during chemical synthesis. To overcome the first problem, we describe the employment of a Computationally Optimised DNA Assembly (CODA) algorithm that uses the degeneracy of the genetic code to design overlapping oligonucleotides with thermodynamic properties for self-assembly into a single, linear, DNA product. To address the second problem, we describe a hierarchical assembly strategy that reduces the incorporation of defective oligonucleotides into full-length gene constructs. The CODA algorithm and these biological methods enable fast, simple and reliable assemblies of sequence-correct full-length genes.

Liza S.Z. Larsen; Christopher D. Wassman; G. Wesley Hatfield; Richard H. Lathrop

2008-01-01T23:59:59.000Z

268

Unscheduled DNA synthesis and mitochondrial DNA synthetic rate following injury of the facial nerve  

Science Journals Connector (OSTI)

Unscheduled DNA synthesis (UDS) of nuclear DNA and mitochondrial (mt) DNA synthetic rates were determined autoradiographically in different cell ... nerve transection. In addition to an increased synthetic rate ...

H. Korr; V. Philippi; C. Helg; J. Schiefer; M. B. Graeber…

1997-11-01T23:59:59.000Z

269

Synthetic Nano-Low Density Lipoprotein as Targeted Drug Delivery Vehicle for Glioblastoma Multiforme  

E-Print Network (OSTI)

Synthetic Nano-Low Density Lipoprotein as Targeted Drugmicroemulsion; peptide; nano-low density lipoproteintherapeutic agents. A synthetic nano-LDL (nLDL) particle was

Nikanjam, Mina; Blakely, Eleanor A.; Bjornstad, Kathleen A.; Shu, Xiao; Budinger, Thomas F.; Forte, Trudy M.

2006-01-01T23:59:59.000Z

270

E-Print Network 3.0 - advanced synthetic aperture Sample Search...  

NLE Websites -- All DOE Office Websites (Extended Search)

of Synthetic Aperture Summary: advanced synthetic aperture focusing tech- niques (SAFT) implemented in frequency domain have been widely... 1399 An Implementation of...

271

Organic Photovoltaics  

Science Journals Connector (OSTI)

Satisfying the world's growing demand for energy is an urgent societal challenge. Organic photovoltaics holds promise as a cost-efficient and environmentally friendly solution.

Kippelen, Bernard

2007-01-01T23:59:59.000Z

272

Nucleic Acid Library Construction Using Synthetic DNA Constructs  

Science Journals Connector (OSTI)

The synthesis of a high-diversity double-stranded DNA pool can require hundreds of milliliters of...3,10...). Large volumes are required because the maximum concentration of single-stranded synthetic DNA template...

Hani S. Zaher; Peter J. Unrau

2005-01-01T23:59:59.000Z

273

Aromatic Interactions in Proteins, DNA and Synthetic Receptors  

Science Journals Connector (OSTI)

...research-article Aromatic Interactions in Proteins, DNA and Synthetic Receptors C. A. Hunter Non-covalent interactions between...and three-dimensional structure in double-helical DNA. The - interaction model has been used to calculate the...

1993-01-01T23:59:59.000Z

274

113 Lab Learning Objectives Week 8: synthetic lab #7  

E-Print Network (OSTI)

113 Lab Learning Objectives Week 8: synthetic lab #7 Learning Objectives for Promoter Discovery Selection Skills · Read DNA sequence and search for SNPs using ApE software. · Determine your PTC tasting

Campbell, A. Malcolm

275

Sequence Specific Recognition of Double Helical DNA. A Synthetic Approach  

Science Journals Connector (OSTI)

The design of synthetic sequence-specific DNA-binding molecules has advanced in recent years ... rapid and precise analyses of hundreds of potential DNA-binding sites to nucleotide resolution on sequencing ... bi...

P. B. Dervan

1988-01-01T23:59:59.000Z

276

Exploiting synthetic lethal interactions for targeted cancer therapy  

E-Print Network (OSTI)

Emerging data suggests that synthetic lethal interactions between mutated oncogenes/tumor suppressor genes and molecules involved in DNA damage signaling and repair can be therapeutically exploited to preferentially kill ...

Jiang, Hai

277

Magnetic behaviour of synthetic Co2SiO4  

Science Journals Connector (OSTI)

The magnetic structure of the synthetic cobalt olivine, Co2SiO4, is determined by means of non-polarized and polarized neutron diffraction on single-crystal and powder samples.

Sazonov, A.

2009-11-16T23:59:59.000Z

278

Wafer-Scale Synthesis of Monodisperse Synthetic Magnetic Multilayer Nanorods  

Science Journals Connector (OSTI)

Wafer-Scale Synthesis of Monodisperse Synthetic Magnetic Multilayer Nanorods ... †Department of Materials Science and Engineering, ‡Department of Mechanical Engineering, and §Department of Electrical Engineering, Stanford University, Stanford, California 94305, United States ...

Mingliang Zhang; Daniel J. B. Bechstein; Robert J. Wilson; Shan X. Wang

2013-12-12T23:59:59.000Z

279

Synthetic strategies for the design of platinum anticancer drug candidates  

E-Print Network (OSTI)

Chapter 1. The Synthetic Chemistry of Platinum Anticancer Agents Since the inception of cisplatin as a clinically approved anticancer agent, a large number of platinum compounds have been synthesized with the aim of finding ...

Wilson, Justin Jeff

2013-01-01T23:59:59.000Z

280

Synthetic approaches to the activation of substituted 2-methyl pyridines  

E-Print Network (OSTI)

increases in the yield and rate of these reactions is an important objective. This thesis describes synthetic approaches to a new class of ligands containing two picolinic acid units conected together by a non-oxidizable chain. An improved procedure...

Cancanon, Fernadina de la Caridad

2012-06-07T23:59:59.000Z

Note: This page contains sample records for the topic "organisms synthetic biology" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


281

Biofuel production by in vitro synthetic enzymatic pathway biotransformation  

NLE Websites -- All DOE Office Websites (Extended Search)

49; 49; NO. OF PAGES 7 Please cite this article in press as: Zhang Y-H P., et al. Biofuel production by in vitro synthetic enzymatic pathway biotransformation, Curr Opin Biotechnol (2010), doi:10.1016/j.copbio.2010.05.005 Available online at www.sciencedirect.com Biofuel production by in vitro synthetic enzymatic pathway biotransformation Y-H Percival Zhang 1,2,3 , Jibin Sun 4 and Jian-Jiang Zhong 5 Cell-free synthetic pathway biotransformation (SyPaB) is the implementation of complicated biochemical reactions by in vitro assembling a number of enzymes or their complexes and coenzymes. Assembly of numerous enzymes without cellular membrane, gene regulation, or undesired pathway can circumvent some of the obstacles to modifying living microorganisms. Several synthetic pathways for the production of liquid biofuels - alcohols and hydrocarbon precursors (polyols)

282

Biological Sciences at NERSC  

NLE Websites -- All DOE Office Websites (Extended Search)

Biological Sciences Biological Sciences Biological Sciences Better knowledge of biomolecules and processes they undergo is vital for achieving a predictive, systems-level understanding of complex biological systems that have potential use in bioenergy, carbon cycling and biosequestration, and biogeochemistry. Areas that NERSC helps to enable include: Research activities using genomics and systems biology to understand plants and microbes. Developing and applying atomistic-molecular to coarse-grained mathematical models of potential energy surfaces, characterizing these surfaces through sampling techniques and finally generating ensemble or time averaged physical properties of biological phenomena. Fundamental research in the redesign of microbial metabolic processes to harness their potential in the conversion of biomass to

283

Energy from the Biological Conversion of Solar Energy [and Discussion  

Science Journals Connector (OSTI)

7 February 1980 research-article Energy from the Biological Conversion of Solar Energy [and Discussion] N. K. Boardman M...are well designed for the collection and storage of solar energy. Moreover, photosynthetic organisms show...

1980-01-01T23:59:59.000Z

284

BE.440 Analysis of Biological Networks, Fall 2004  

E-Print Network (OSTI)

This class analyzes complex biological processes from the molecular, cellular, extracellular, and organ levels of hierarchy. Emphasis is placed on the basic biochemical and biophysical principles that govern these processes. ...

Essigmann, John

285

Biological Factors in Treatment of Raw Sewage in Artificial Ponds  

Science Journals Connector (OSTI)

be improved. Accordingly ... Various factors, such as loading, solar ..... example, follows changes in air temperature .... In these observations ice quality appeared ... of solar energy by aquatic organisms. Problems in. Lake Biology;. A.A.A.S..

1999-12-13T23:59:59.000Z

286

Structural Molecular Biology, SSRL  

NLE Websites -- All DOE Office Websites (Extended Search)

Biological Small Angle X-ray Scattering Workshop The SSRL Structural Molecular Biology Group hosted a 3-day comprehensive workshop on the use of non-crystalline small-angle...

287

Structural Biology | Biosciences Division  

NLE Websites -- All DOE Office Websites (Extended Search)

Photosynthetic Photosynthetic Reaction Center BIO Home Page About BIO News Releases Research Publications People Contact Us Organization Chart Site Index Inside BIO BIO Safety About Argonne Membrane Protein Engineering Photosynthetic reaction center: A novel quantum electronic circuit element Living cells contain a large variety of biomolecular complexes which self-assemble, recognize and control each other. These nanoscale devices, referred to as bionanodevices, perform critical cell functions such as gene expression, energy conversion, motion, signaling and metabolism. Recent advances in nanotechnology have paved the way to new possibilities and challenges for integrating highly efficient bionanodevices, designed and perfected by Nature during billions of years of evolution, into useful electronic devices. The main scientific and technological challenge in achieving this goal is the successful linkage of the biological components with the conventional, inorganic components. We are developing, implementing, and characterizing a new photobioelectronic device which converts light energy (photons) into an electronic signal by using the photosynthetic reaction center of purple bacteria as the active photoelement

288

Organic geochemistry and organic petrography  

SciTech Connect

The Vermillion Creek coals and shales contain dominantly humic organic matter originating from woody plant tissues except for one shale unit above the coals, which contains hydrogen-rich kerogen that is mostly remains of filamentous algae, of likely lacustrine origin. The coals have two unusual features - very low inertinite content and high sulfur content compared to mined western coals. However, neither of these features points to the limnic setting reported for the Vermillion Creek sequence. The vitrinite reflectance of Vermillion Creek shales is markedly lower than that of the coals and is inversely proportional to the H/C ratio of the shales. Rock-Eval pyrolysis results, analyses of H, C, and N, petrographic observations, isotope composition of organic carbon, and amounts and compositions of the CHCl/sub 3/-extractable organic matter all suggest mixtures of two types of organic matter in the Vermillion Creek coals and clay shales: (1) isotopically heavy, hydrogen-deficient, terrestrial organic matter, as was found in the coals, and (2) isotopically light, hydrogen-rich organic matter similar to that found in one of the clay-shale samples. The different compositions of the Vermillion Creek coal, the unnamed Williams Fork Formation coals, and coals from the Middle Pennsylvanian Marmaton and Cherokee Groups are apparently caused by differences in original plant composition, alteration of organic matter related to different pH conditions of the peat swamps, and slightly different organic maturation levels.

Bostick, N.H.; Hatch, J.R.; Daws, T.A.; Love, A.H.; Lubeck, S.C.M.; Threlkeld, C.N.

1987-01-01T23:59:59.000Z

289

Systems biology approach to bioremediation  

E-Print Network (OSTI)

aspects of the systems biology approach (metagenomics withthe use of a number of sytems biology parameters can revealRL, Banfield JF: Systems Biology: functional analysis of

Chakraborty, R.

2013-01-01T23:59:59.000Z

290

HARVARD UNIVERSITY CHEMICAL BIOLOGY  

E-Print Network (OSTI)

HARVARD UNIVERSITY CHEMICAL BIOLOGY PHD PROGRAM 2013-2014 Student Handbook #12;Program Contacts at the beginning of each semester. Laboratory Rotations Students in the Chemical Biology Program are expected an interest in having Chemical Biology Program Students in their labs. Students may rotate in the labs

Church, George M.

291

Careers with Forensic Biology  

E-Print Network (OSTI)

Careers with Forensic Biology www.twitter.com/mmu_careers www.facebook.com/MMUCareersandEmployability Careers & Employability Service www.mmu.ac.uk/careers/guides #12;2 08/12 Careers with Forensic Biology These are a range of careers and employers that would use and value your forensic biology knowledge: Laboratory

292

De Novo Metabolic Engineering and the Promise of Synthetic DNA  

Science Journals Connector (OSTI)

Improving a host organism’s cellular traits and the potential design of new phenotypes is strongly dependent on the ability to effectively control the organism’s genetic machinery. In fact, finely-tuned gene expr...

Daniel Klein-Marcuschamer; Vikramaditya G. Yadav; Adel Ghaderi…

2010-01-01T23:59:59.000Z

293

Analysis of differences in productivity, profitability and soil fertility between organic and conventional cropping systems in the (sub)tropics   

E-Print Network (OSTI)

Organic farming, which aims at increasing soil fertility by avoiding synthetic inputs and using locally available natural resources, is regarded as a sustainable alternative to conventional farming because it ensures ...

te Pas, Caroline M.

2011-11-24T23:59:59.000Z

294

Function of transcription termination factor .rho. in a model transcription system using synthetic DNA as template  

Science Journals Connector (OSTI)

Function of transcription termination factor .rho. in a model transcription system using synthetic DNA as template ...

Katsuya Shigesada; Mutsuo Imai

1982-11-01T23:59:59.000Z

295

Structure and Photoinduced Electron Transfer in Exceptionally Stable Synthetic DNA Hairpins with Stilbenediether Linkers  

Science Journals Connector (OSTI)

Structure and Photoinduced Electron Transfer in Exceptionally Stable Synthetic DNA Hairpins with Stilbenediether Linkers ...

Frederick D. Lewis; Xiaoyang Liu; Yangsheng Wu; Scott E. Miller; Michael R. Wasielewski; Robert L. Letsinger; Ruslan Sanishvili; Andrzej Joachimiak; Valentina Tereshko; Martin Egli

1999-10-13T23:59:59.000Z

296

Integrating physical and genetic interaction networks for biological pathway discovery  

E-Print Network (OSTI)

the synthetic lethal relationship between the DNA repairDNA helicase gene interaction network defined using syntheticDNA helicase gene interaction network defined using synthetic

Bandyopadhyay, Sourav

2010-01-01T23:59:59.000Z

297

Concurrent Connection of Embryonic Chick Heart Using a Microfluidic Device for Organ-Explant-Chip  

E-Print Network (OSTI)

We propose a concurrent microvascular connection method called suction-induced vascular fixation (SVF) method for the achievement of Organ-Explant-Chip which is a biologically-designed simulator having biological materials ...

Owaki, Hirofumi

298

Material nanosizing effect on living organisms: non-specific, biointeractive, physical size effects  

Science Journals Connector (OSTI)

...Introduction 1.1 Nanotechnology and biological organisms The development of nanotechnology has a large influence...investigated in biology and medicine. For materials...Graduate School of Dental Medicine, Hokkaido University...Nanostructures chemistry Nanotechnology Nanotubes, Carbon...

2009-01-01T23:59:59.000Z

299

Use of synthetic DNA in expression of foreign proteins  

Science Journals Connector (OSTI)

Synthetic \\{DNAs\\} and oligonucleotides, which can be prepared conveniently by combining chemical synthesis and enzymatic methods, have been used extensively in recombinant DNA research. Examples include total gene synthesis, probes for the isolation of specific genes from cDNA or genomic libraries, linkers containing specific restriction sites for cloning, primers for DNA and RNA sequencing, and primers for the construction of specific mutations (either deletion, insertion or point mutations) by oligonucleotide-directed site-specific mutagenesis. This article reviews recent advances in the chemical and enzymatic synthesis of oligo- and polynucleotides and the application of synthetic DNA to the expression of foreign proteins. The synthesis of genes, including structural genes and regulatory genes are reviewed. Oligonucleotide-directed site-specific mutagenesis and use of synthetic DNA to optimize foreign protein expression are also discussed.

Hansen M. Hsiung

1986-01-01T23:59:59.000Z

300

Integrating synthetic flood data for selection of regional frequency distribution  

Science Journals Connector (OSTI)

Regional frequency distributions are estimated using respective regional average coefficients of variance, skewness and kurtosis. The regional average coefficients may be significantly biased for a region with inadequate hydrometric data. The objective of this study is to select suitable regional frequency distributions in previously identified five hydrologic homogeneous regions of Nepalese territory with larger focus on data-scarce regions. Incorporation of synthetic flood data has been proposed in two hydrologic regions which have insufficient hydrometric data. A SimHyd rainfall runoff model was employed for the generation of synthetic flood data to augment hydrometric data inadequacy. Selection of best-fit regional frequency distribution was identified using L-moment ratio diagrams and goodness-of-fit measure. The selected distributions were tested by comparing observation and regional distribution factors at eight observation hydrometric sites. Incorporation of synthetic flood data enabled to reduce regional distribution factor error to 6% from that of 10%.

Binaya Kumar Mishra; Kaoru Takara

2014-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "organisms synthetic biology" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


301

2013 METALS IN BIOLOGY GORDON RESEARCH CONFERENCE, JANUARY 20-25, 2013  

SciTech Connect

Typical topics for lectures and posters include: biochemical and biophysical characterization of new metal containing proteins, enzymes, nucleic acids, factors, and chelators from all forms of life; synthesis, detailed characterization, and reaction chemistry of biomimetic compounds; novel crystal and solution structures of biological molecules and synthetic metal-chelates; discussions of the roles that metals play in medicine, maintenance of the environment, and biogeochemical processes; metal homeostasis; application of theory and computations to the structure and mechanism of metal-containing biological systems; and novel applications of spectroscopy to metals in biological systems.

Rosenzweig, Amy

2013-01-25T23:59:59.000Z

302

Evaluation of synthetic aggregates for use in concrete  

E-Print Network (OSTI)

of synthetic aggregates may result in 4 irregular aggrege. te behavior with respect to those test procedures. Investigators at the Texas Transportation Institute have sug- g sted some new r. echniques to evaluate the synthet. ic ageregate. Some... in firing temperature and retention t5me, although pressure s1aking losses of all ag, regates were very low which indicated that the dehydration process of all aggro ates wa complete. 11. The NuOH test was able to detect the vari. ation of aggre- gate...

Ahmad, Hafizuddin

1970-01-01T23:59:59.000Z

303

Synthetic investigations into the hexasaccharide domain of landomycin A  

E-Print Network (OSTI)

. 1 Preparation of Disaccharide 14 Our synthetic schemes starts with the formation of the ct-linkage between L- rhodinose and D-olivose. Of the many available methods used to introduce 2-deoxy-ct- glycoside linkages, we chose to employ glycosyl.... 1 Preparation of Disaccharide 14 Our synthetic schemes starts with the formation of the ct-linkage between L- rhodinose and D-olivose. Of the many available methods used to introduce 2-deoxy-ct- glycoside linkages, we chose to employ glycosyl...

Kuo, Yu

2012-06-07T23:59:59.000Z

304

DOI: 10.1002/chem.201001549 Post-Synthetic Reversible Incorporation of Organic Linkers into Porous  

E-Print Network (OSTI)

transformations. Interestingly, the bridging ligand 3,6- di(4-pyridyl)-1,2,4,5-tetrazine (bpta), which is linear)-1,2,4,5-tetrazine (bpta) affords single-crystalline {[Zn2- ACHTUNGTRENNUNG

Paik Suh, Myunghyun

305

The removal kinetics of industrial organic compounds in natural and synthetic systems  

E-Print Network (OSTI)

techniques of most interest are; least squares curve fitting of non-linear functions, differentiation and integration of data wh1ch are not equally spaced, and interpolation - extrapolation (5, 15). The capability of presenting different kinetic...

Petrasek, Albert Charles

1970-01-01T23:59:59.000Z

306

PubChem: Integrated Platform of Small Molecules and Biological Activities Evan E. Bolton1  

E-Print Network (OSTI)

PubChem: Integrated Platform of Small Molecules and Biological Activities Evan E. Bolton1 , Yanli organizations. PubChem provides a significant, publicly accessible platform for mining the biological information of small molecules. Keywords Database, repository, chemical structures, assay, biological activity

Levin, Judith G.

307

Systems biology: From the cell to the brain SITABHRA SINHA1,  

E-Print Network (OSTI)

Systems biology: From the cell to the brain SITABHRA SINHA1, , T JESAN2 and NIVEDITA CHATTERJEE3 1 genome mapping, the focus of scientists seeking to explain the biological complexity of living systems functions of the organism. To this end, the area of systems biology attempts to achieve a `systems

Joshi, Yogesh Moreshwar

308

NEWTON's Molecular Biology References  

NLE Websites -- All DOE Office Websites (Extended Search)

Molecular Biology References Molecular Biology References Do you have a great reference link? Please click our Ideas page. Featured Reference Links: The Vitual Museum of Bacteria The Vitual Museum of Bacteria Visit the virtual museum of bacteria to learn more about bacteria and germs! This site brings together many links on bacteria, bacteriology, and related topics available on the web. It also provides crystal-clear information about many aspects of bacteria. The American Society of Cell Biology Cell Biology Educational Resources This site, sponsered by the American Society of Cell Biology, provides additional web links to everything from, general educational sites, to biology course materials, to teaching tools and more. National Center for Biotechnology Information National Center for Biotechnology Information

309

Insect Controls for Organic Gardeners.  

E-Print Network (OSTI)

gardening has increased in recent years. Organic gardening means enriching the garden soil with natural products (mulches, composts and animal manures) and controlling insects, diseases and weeds with cultural, mechanical and biological methods rather... damage. However, excessive amounts of compost or manure can encourage millipedes, white grubs and certain other pests. Changes in planting or harvesting time often will reduce plant damage or keep insect pests separated from susceptible stages...

Lewis, Kenneth R.; Turney, H.A.

1979-01-01T23:59:59.000Z

310

Theory of Biological Cleanroom  

Science Journals Connector (OSTI)

Modern biological cleanroom was developed on the basis of the industrial cleanroom. Except for the common principles of the cleanroom, the specific principles for the control of...

Zhonglin Xu

2014-01-01T23:59:59.000Z

311

Applicant Organization:  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

ALICO, Inc. ALICO, Inc. Corporate HQ: LaBelle, Hendry County, Florida Proposed Facility Location: LaBelle, Florida Description: This company is a major agricultural company that will use an innovative thermochemical technology company that ferments synthesis gas. This thermochemical/fermentation conversion alternative could be suitable to feedstocks that are not easily processed biologically such as wood and wood wastes. CEO or Equivalent: John Alexander Participants: Bioengineering Resources, Inc. of Fayetteville, Arkansas; Washington Group International of Boise, Idaho; GeoSyntec Consultants of Boca Raton, Florida; BG Katz Companies/JAKS,LLC of Parkland, Florida; Emmaus Foundation, Inc. Production: * Ethanol, electricity, ammonia and hydrogen

312

3 - Preparation of feedstocks for gasification for synthetic liquid fuel production  

Science Journals Connector (OSTI)

Abstract Gasification has been considered as a potential thermo-chemical method of conversion to effectively utilize the carbon (organic content) present in the feedstock. Preparation and handling methods of some of the potential feedstocks (i.e., coal, petroleum residue, biomass, and municipal solid waste (MSW) to produce the synthetic gas) for various applications are discussed. The pre-treatment process for feedstock constitutes the steps that must be imposed on the raw material in preparation for use in a gasification reactor. The properties of fuel that influence the gasification are energy content, moisture content, particle size and distribution, form of the fuel, bulk density of the fuel, volatile matter content, ash content, and composition and reactivity of the fuel.

B. Bhavya; R. Singh; T. Bhaskar

2015-01-01T23:59:59.000Z

313

Physics Pathway: A Digital Library Filled with Synthetic Interviews*  

E-Print Network (OSTI)

Physics Pathway: A Digital Library Filled with Synthetic Interviews* Michael G. Christel-412-268-7796 sms@cs.cmu.edu Dean Zollman Department of Physics Kansas State University Manhattan, KS 66506 1-785-532-1619 dzollman@phys.ksu.edu ABSTRACT Physics Pathway is a digital library available through an Adobe Flash portal

Christel, Mike

314

Experimental pressure solution compaction of synthetic halite/calcite aggregates  

E-Print Network (OSTI)

Experimental pressure solution compaction of synthetic halite/calcite aggregates Sergey Zubtsova of weakening of sediment-like aggregates by addition of hard particles. Sieved mixtures of calcite and halite solution. The individual halite grains deform easily by pressure solution creep whereas calcite grains act

315

Synthetic aperture design for increased SAR image rate  

DOE Patents (OSTI)

High resolution SAR images of a target scene at near video rates can be produced by using overlapped, but nevertheless, full-size synthetic apertures. The SAR images, which respectively correspond to the apertures, can be analyzed in sequence to permit detection of movement in the target scene.

Bielek, Timothy P. (Albuquerque, NM); Thompson, Douglas G. (Albuqerque, NM); Walker, Bruce C. (Albuquerque, NM)

2009-03-03T23:59:59.000Z

316

THE DEVELOPMENT OF NEW OR IMPROVED SYNTHETIC MATERIALS FROM CORN  

E-Print Network (OSTI)

of materials will diversify the market for corn and for wet- mill biorefineries." Jaffe said that the workTHE DEVELOPMENT OF NEW OR IMPROVED SYNTHETIC MATERIALS FROM CORN DERIVATIVES IS THE GOAL OF A PARTNERSHIP AMONG NJIT RESEARCHERS, THE IOWA CORN PROMOTION BOARD AND THE MID-ATLANTIC TECHNOLOGY, RESEARCH

Bieber, Michael

317

More U. S. , Canada synthetic rubber use seen  

SciTech Connect

According to M.J. Rhoad of the International Institute of Synthetic Rubber Producers Inc., the total U.S. and Canadian natural and synthetic rubber consumption will amount to (in thousands of metric tons/yr) 3385, 3305, 3855, and 4295 for 1979, 1980, 1985, and 1990, respectively, with synthetic rubber use increasing from an estimated 2.54 million metric tons/yr in 1979 to 3.27 million metric tons/yr by 1990, including an increase from 2.35 to 3.02 million metric tons/yr for the U.S. Rubber consumption for tires and tire products in the U.S. will increase at 2%/yr, with synthetic rubber accounting for 61.9% of the rubber used for tires in 1990, down from the 63.4% in 1979. In 1980, the decline in automobile and tire production will cause a 2.4% decline in new rubber consumption. During 1979-90, the amount of rubber used for nontire purposes will increase at 2.5%/yr.

Rhoad, M.J.

1980-02-04T23:59:59.000Z

318

Susceptibility of Synthetic Long-Chain Alkylbenzenes to  

E-Print Network (OSTI)

Susceptibility of Synthetic Long-Chain Alkylbenzenes to Degradation in Reducing Marine Sediments R Sunrise Valley Drive, Reston, Virginia 20192 Received April 24, 2008. Revised manuscript received June 24, 2008. Accepted July 02, 2008. Long-chain alkylbenzenes (LCABs) synthesized for production

319

USING SYNTHETIC PLAYERS TO GENERATE WORKLOADS FOR NETWORKED MULTIPLAYER GAMES  

E-Print Network (OSTI)

that generates appropriate workloads for networked multiplayer games. Based on this framework, we have developed a software infrastructure and a prototype synthetic player for the multiplayer adventure game Crossfire Video games have been projected to continue to enjoy solid growth over the coming years (PricewaterhouseCoopers

Katchabaw, Michael James

320

MULTISPECTRAL SYNTHETIC SCENE GENERATION USING ATMOSPHERIC PROPAGATION AND THERMODYNAMIC MODELS  

E-Print Network (OSTI)

of the Central Intelligence Agency, the US Department of Energy, NASA's Jet Propulsion Laboratory, ITEK a requirement. This document represents the current status of a first-principles physics-based synthetic image behavior in a natural environment, and the propagation of energy through the atmosphere. The model

Salvaggio, Carl

Note: This page contains sample records for the topic "organisms synthetic biology" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


321

E-Print Network 3.0 - actin cytoskeleton organization Sample...  

NLE Websites -- All DOE Office Websites (Extended Search)

University Collection: Chemistry ; Biology and Medicine 60 ORIGINAL ARTICLE Alenka Lovy-Wheeler Kathleen L. Wilsen Summary: and organization of the actin cytoskeleton....

322

Biology and Soft Matter Division - ORNL Neutron Sciences  

NLE Websites -- All DOE Office Websites (Extended Search)

Home › Neutron Sciences Directorate › Biology and Soft Matter Division Home › Neutron Sciences Directorate › Biology and Soft Matter Division Biology and Soft Matter Division Paul Langan, BSMD Director BSMD Director Paul Langan. The Biology and Soft Matter Division (BSMD) operates an external user program for biological and soft matter research using neutron techniques at SNS and HFIR. Division personnel enable the research initiated by external users by acting as instrument responsible scientists and local contacts on a range of different beam lines. BSMD works closely with the Center for Structural Molecular Biology. Diffraction, small-angle scattering, and reflectometry are ideal methods for studying structure and organization from the atomic to the micron length scales, and neutron spectroscopic methods characterize self and

323

Biology and Soft Matter Division | Neutron Science | ORNL  

NLE Websites -- All DOE Office Websites (Extended Search)

Biology and Soft Matter Division Biology and Soft Matter Division SHARE Biology and Soft Matter Division BSMD Director Paul Langan The Biology and Soft Matter Division (BSMD) operates an external user program for biological and soft matter research using neutron techniques at SNS and HFIR. Division personnel enable the research initiated by external users by acting as instrument responsible scientists and local contacts on a range of different beam lines. BSMD works closely with the Center for Structural Molecular Biology. Diffraction, small-angle scattering, and reflectometry are ideal methods for studying structure and organization from the atomic to the micron length scales, and neutron spectroscopic methods characterize self and collective motions from picosecond to microsecond timescales. These

324

ECOLOGY & EVOLUTION CONSERVATION BIOLOGY  

E-Print Network (OSTI)

.arlettaz@iee.unibe.ch www.conservation.unibe.ch Grassland management: designing tomorrow's farmland for biodiversity 1ECOLOGY & EVOLUTION CONSERVATION BIOLOGY Prof. Dr Raphaël Arlettaz Head of the division of Conservation Biology Office: Erlachstrasse 9a Mail: Baltzerstrasse 6 CH­3012 Bern +41 31 631 31 61 +41 79 637

Richner, Heinz

325

NANOTECHNOLOGY IN BIOLOGY AND  

E-Print Network (OSTI)

NANOTECHNOLOGY IN BIOLOGY AND MEDICINE Methods, Devices, and Applications #12;CRC Press Taylor to infringe. Library of Congress Cataloging-in-Publication Data Nanotechnology in biology and medicine. paper) 1. Nanotechnology. 2. Biomedical engineering. 3. Medical technology. I. Vo-Dinh, Tuan. [DNLM: 1

Pennycook, Steve

326

Integrated Biological Control  

SciTech Connect

Biological control is any activity taken to prevent, limit, clean up, or remediate potential environmental, health and safety, or workplace quality impacts from plants, animals, or microorganisms. At Hanford the principal emphasis of biological control is to prevent the transport of radioactive contamination by biological vectors (plants, animals, or microorganisms), and where necessary, control and clean up resulting contamination. Other aspects of biological control at Hanford include industrial weed control (e.g.; tumbleweeds), noxious weed control (invasive, non-native plant species), and pest control (undesirable animals such as rodents and stinging insects, and microorganisms such as molds that adversely affect the quality of the workplace environment). Biological control activities may be either preventive (a priori) or in response to existing contamination spread (a posteriori). Surveillance activities, including ground, vegetation, flying insect, and other surveys, and a priori control actions, such as herbicide spraying and placing biological barriers, are important in preventing radioactive contamination spread. If surveillance discovers that biological vectors have spread radioactive contamination, a posteriori control measures, such as fixing contamination, followed by cleanup and removal of the contamination to an approved disposal location are typical response functions. In some cases remediation following the contamination cleanup and removal is necessary. Biological control activities for industrial weeds, noxious weeds and pests have similar modes of prevention and response.

JOHNSON, A.R.

2003-10-09T23:59:59.000Z

327

Integrated Biological Control  

SciTech Connect

Biological control is any activity taken to prevent, limit, clean up, or remediate potential environmental, health and safety, or workplace quality impacts from plants, animals, or microorganisms. At Hanford the principal emphasis of biological control is to prevent the transport of radioactive contamination by biological vectors (plants, animals, or microorganisms), and where necessary, control and clean up resulting contamination. Other aspects of biological control at Hanford include industrial weed control (e.g.; tumbleweeds), noxious weed control (invasive, non-native plant species), and pest control (undesirable animals such as rodents and stinging insects; and microorganisms such as molds that adversely affect the quality of the workplace environment). Biological control activities may be either preventive (apriori) or in response to existing contamination spread (aposteriori). Surveillance activities, including ground, vegetation, flying insect, and other surveys, and apriori control actions, such as herbicide spraying and placing biological barriers, are important in preventing radioactive contamination spread. If surveillance discovers that biological vectors have spread radioactive contamination, aposteriori control measures, such as fixing contamination, followed by cleanup and removal of the contamination to an approved disposal location are typical response functions. In some cases remediation following the contamination cleanup and removal is necessary. Biological control activities for industrial weeds, noxious weeds and pests have similar modes of prevention and response.

JOHNSON, A.R.

2002-09-01T23:59:59.000Z

328

PNNL: Biological Sciences: Fundamental and Computational Sciences  

NLE Websites -- All DOE Office Websites (Extended Search)

We perform Biological Systems Science research using prediction and We perform Biological Systems Science research using prediction and experimentation to understand the design of biological systems, translating the genome to functional capabilities for applications to energy, environment, and health. Microbial community research at PNNL is focusing on environment and energy processes, and rational design and development of new bioprocesses, while our health-related research is centering on how multicellular systems, tissues and organisms respond to disease and exposure to the environment. Dayle Smith PNNL and Collaborators Receive ARPA-E Award for Gas-to-Liquid Fuel Biocatalysis Congratulations to Pacific Northwest National Laboratory computational scientist Dr. Dayle Smith, who is part of a team that recently received a

329

Catalyst for splitting water &Catalyst for splitting water & Synthetic Modeling of InorganicSynthetic Modeling of Inorganic  

E-Print Network (OSTI)

Importance Hydrogen technology in fuel cellsHydrogen technology in fuel cells As a combustion fuel, it producesCatalyst for splitting water &Catalyst for splitting water & Synthetic Modeling of Inorganic of evolution ·Optimized catalyst for water splitting in all oxygenic phototrophs S0 S4 S1 S2 S3 O2 2 H O2 e- e

Petta, Jason

330

Applicant Organization:  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

BlueFire Ethanol, Inc. BlueFire Ethanol, Inc. Corporate HQ: Irvine, Orange County, California Proposed Facility Location: Southern California Description: This company has experience building biomass power plants in California and their technology has been demonstrated at the pilot scale. One of its partners is Waste Management Inc., a leading waste-to-energy company. This project will give DOE understanding of a new biological fermentation process not using enzymes. CEO or Equivalent: Arnold Klann Participants: Waste Management, Inc., JGC Corporation; MECS Inc.; NAES; PetroDiamond Production: * 19 million gallons/year in the unit in which DOE will be participating. Technology & Feedstocks: * Concentrated acid processing of 700 tons/day of sorted green waste and wood

331

Applicant Organization:  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

BlueFire Ethanol, Inc. BlueFire Ethanol, Inc. Corporate HQ: Irvine, Orange County, California Proposed Facility Location: Southern California Description: This company has experience building biomass power plants in California and their technology has been demonstrated at the pilot scale. One of its partners is Waste Management Inc., a leading waste-to-energy company. This project will give DOE understanding of a new biological fermentation process not using enzymes. CEO or Equivalent: Arnold Klann Participants: Waste Management, Inc., JGC Corporation; MECS Inc.; NAES; PetroDiamond Production: * 19 million gallons/year in the unit in which DOE will be participating. Technology & Feedstocks: * Concentrated acid processing of 700 tons/day of sorted green waste and wood

332

Dynamics of Photoinduced Charge Separation and Charge Recombination in Synthetic DNA Hairpins with Stilbenedicarboxamide Linkers  

Science Journals Connector (OSTI)

Dynamics of Photoinduced Charge Separation and Charge Recombination in Synthetic DNA Hairpins with Stilbenedicarboxamide Linkers ... The dynamics of photoinduced charge separation and charge recombination in synthetic DNA hairpins have been investigated by means of femtosecond and nanosecond transient spectroscopy. ...

Frederick D. Lewis; Taifeng Wu; Xiaoyang Liu; Robert L. Letsinger; Scott R. Greenfield; Scott E. Miller; Michael R. Wasielewski

2000-03-14T23:59:59.000Z

333

Creating Protein Affinity Reagents by Combining Peptide Ligands on Synthetic DNA Scaffolds  

Science Journals Connector (OSTI)

Creating Protein Affinity Reagents by Combining Peptide Ligands on Synthetic DNA Scaffolds ... The peptides were conjugated to synthetic DNA (Table S4 and S5, SI) using standard amine coupling chemistry(23) (Scheme 1, SI). ...

Berea A. R. Williams; Chris W. Diehnelt; Paul Belcher; Matthew Greving; Neal W. Woodbury; Stephen A. Johnston; John C. Chaput

2009-11-06T23:59:59.000Z

334

Low-Resolution Reconstruction of a Synthetic DNA Holliday Junction Marcelo Nollmann,*y  

E-Print Network (OSTI)

Low-Resolution Reconstruction of a Synthetic DNA Holliday Junction Marcelo No¨llmann,*y W. Marshall

Nollmann, Marcelo

335

Method and apparatus for removing heat from electronic devices using synthetic jets  

DOE Patents (OSTI)

An apparatus for removing heat comprises a heat sink having a cavity, and a synthetic jet stack comprising at least one synthetic jet mounted within the cavity. At least one rod and at least one engaging structure to provide a rigid positioning of the at least one synthetic jet with respect to the at least one rod. The synthetic jet comprises at least one orifice through which a fluid is ejected.

Sharma, Rajdeep; Weaver, Jr., Stanton Earl; Seeley, Charles Erklin; Arik, Mehmet; Icoz, Tunc; Wolfe, Jr., Charles Franklin; Utturkar, Yogen Vishwas

2014-04-15T23:59:59.000Z

336

Electroporation of Synthetic DNA Antigens Offers Protection in Nonhuman Primates Challenged with Highly Pathogenic Avian Influenza Virus  

Science Journals Connector (OSTI)

...ANTIVIRAL AGENTS Electroporation of Synthetic DNA Antigens Offers Protection in...and in vivo electroporation of synthetic DNA-encoded antigens, we observed...recommendationvaccine.pdf . Electroporation of synthetic DNA antigens offers protection in...

Dominick J. Laddy; Jian Yan; Amir S. Khan; Hanne Andersen; Amanda Cohn; Jack Greenhouse; Mark Lewis; Jody Manischewitz; Lisa R. King; Hana Golding; Ruxandra Draghia-Akli; David B. Weiner

2009-02-11T23:59:59.000Z

337

Polymerase chain reaction and synthetic DNA probes: a means of distinguishing the causative agents of syphilis and yaws?  

Science Journals Connector (OSTI)

...Polymerase chain reaction and synthetic DNA probes: a means of distinguishing...Bilthoven, The Netherlands. Synthetic DNA probes specific for either the...Polymerase chain reaction and synthetic DNA probes: a means of distinguishing...

G T Noordhoek; B Wieles; J J van der Sluis; J D van Embden

1990-06-01T23:59:59.000Z

338

Synthetic DNA Replication Bubbles Bound and Unwound with Twofold Symmetry by a Simian Virus 40 T-Antigen Double Hexamer  

Science Journals Connector (OSTI)

ARTICLE ANIMAL VIRUSES Synthetic DNA Replication Bubbles Bound and...examined the binding of TAgDH to synthetic DNA replication bubbles. Tests of...characterized the binding and unwinding of synthetic DNA replication bubbles by the TAgDH...

Natalia V. Smelkova; James A. Borowiec

1998-11-01T23:59:59.000Z

339

BIOLOGICAL SAFETY TABLE OF CONTENTS  

E-Print Network (OSTI)

SERVICES BIOLOGICAL AND CHEMICAL SAFETY PROGRAM...4 1.3 LABORATORY MANAGEMENT COMMITTEE.........................................5 2.0 GENERAL GUIDELINES FOR HANDLING BIOLOGICAL AGENTS...........................................................11 5.0 TRANSPORTATION AND TRANSFER OF BIOLOGICAL AGENTS ........................11 5.1 INTRODUCTION

O'Toole, Alice J.

340

Discrete Assembly of Synthetic Peptide-DNA Triplex Structures from Polyvalent Melamine-Thymine Bifacial Recognition  

E-Print Network (OSTI)

Discrete Assembly of Synthetic Peptide-DNA Triplex Structures from Polyvalent Melamine decadeoxyoligothymi- dine (dT10) tracts to form triplexes with a peptide-DNA strand ratio of 1:2. The synthetic, synthetic melamine-displaying peptide 1 induced assembly of a peptide-DNA triplex structures

Bong, Dennis

Note: This page contains sample records for the topic "organisms synthetic biology" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


341

Comparison of genomic, plasmid, synthetic, and combined DNA probes for detecting Plasmodium falciparum DNA.  

Science Journals Connector (OSTI)

...pRepHind, and a 21-base-long synthetic DNA probe (PFR1), the sequence...second brief hybridization with synthetic DNA to amplify signals from samples...pRepHind, and a 21-base-long synthetic DNA probe (PFR1), the sequence...

G L McLaughlin; W E Collins; G H Campbell

1987-05-01T23:59:59.000Z

342

Dynamics of Photoinduced Charge Transfer and Hole Transport in Synthetic DNA Hairpins  

Science Journals Connector (OSTI)

Dynamics of Photoinduced Charge Transfer and Hole Transport in Synthetic DNA Hairpins ... The dynamics of photoinduced charge separation and charge recombination processes in synthetic DNA hairpins have been investigated by means of femtosecond transient absorption spectroscopy. ... for a family of synthetic DNA hairpins in which a stilbene dicarboxamide forms a bridge connecting two oligonucleotide arms. ...

Frederick D. Lewis; Robert L. Letsinger; Michael R. Wasielewski

2000-12-13T23:59:59.000Z

343

Development of natural and synthetic DNA probes for OXA-2 and TEM-1 beta-lactamases.  

Science Journals Connector (OSTI)

...Article Development of natural and synthetic DNA probes for OXA-2 and TEM-1...polymorphism. Development of natural and synthetic DNA probes for OXA-2 and TEM-1...5 Development of Natural and Synthetic DNA Probes for OXA-2 and TEM-1...

M Boissinot; J Mercier; R C Levesque

1987-05-01T23:59:59.000Z

344

A set of Macintosh computer programs for the design and analysis of synthetic genes  

Science Journals Connector (OSTI)

......are given for the creation of synthetic DNA sequences for the bovine prethrombin-2...are given for the creation of synthetic DNA sequences for the bovine prethrombin-2...are given for the creation of synthetic DNA sequences for the bovine prethrombin-2......

M. P. Weiner; H.A. Scheraga

1989-07-01T23:59:59.000Z

345

Fusion of multiple image types for the creation of radiometrically-accurate synthetic scenes  

E-Print Network (OSTI)

Fusion of multiple image types for the creation of radiometrically-accurate synthetic scenes-in-the-loop requirements for many aspects of synthetic hyperspectral scene construction. Through a fusion of 3D lidar data: lidar, hyperspectral, fusion, DIRSIG, building reconstruction, synthetic scene 1 INTRODUCTION Over

Kerekes, John

346

Effect of Synthetic Drilling Fluid Base Oils on Asphaltene Stability and Wetting in Sandstone Cores  

Science Journals Connector (OSTI)

Effect of Synthetic Drilling Fluid Base Oils on Asphaltene Stability and Wetting in Sandstone Cores† ... In synthetic oil-based drilling fluids, diesel has been replaced, for environmental reasons, by base oils that are very low in aromatic hydrocarbons. ... Paraffinic and olefinic base oils used to make up some synthetic oil-based drilling muds can destabilize asphaltenes. ...

Yongsheng Zhang; Jianxin Wang; Norman R. Morrow; Jill S. Buckley

2005-03-18T23:59:59.000Z

347

Biological & Environmental Research Abstracts Database  

Office of Scientific and Technical Information (OSTI)

Welcome to the Biological and Environmental Research Abstracts Database The U.S. Department of Energy's Office of Biological and Environmental Research (BER) conducts research in...

348

Green Biologics | Open Energy Information  

Open Energy Info (EERE)

Biologics Jump to: navigation, search Name: Green Biologics Place: Oxfordshire, United Kingdom Sector: Biomass, Renewable Energy Product: Oxfordshire-based industrial biotech...

349

Synthetic aperture integration (SAI) algorithm for SAR imaging  

DOE Patents (OSTI)

A method and system for detecting the presence of subsurface objects within a medium is provided. In some embodiments, the imaging and detection system operates in a multistatic mode to collect radar return signals generated by an array of transceiver antenna pairs that is positioned across the surface and that travels down the surface. The imaging and detection system pre-processes the return signal to suppress certain undesirable effects. The imaging and detection system then generates synthetic aperture radar images from real aperture radar images generated from the pre-processed return signal. The imaging and detection system then post-processes the synthetic aperture radar images to improve detection of subsurface objects. The imaging and detection system identifies peaks in the energy levels of the post-processed image frame, which indicates the presence of a subsurface object.

Chambers, David H; Mast, Jeffrey E; Paglieroni, David W; Beer, N. Reginald

2013-07-09T23:59:59.000Z

350

Topologically Robust Transport of Photons in a Synthetic Gauge Field  

E-Print Network (OSTI)

Electronic transport in low dimensions through a disordered medium leads to localization. The addition of gauge fields to disordered media leads to fundamental changes in the transport properties. For example, chiral edge states can emerge in two-dimensional systems with a perpendicular magnetic field. Here, we implement a "synthetic'' gauge field for photons using silicon-on-insulator technology. By determining the distribution of transport properties, we confirm the localized transport in the bulk and the suppression of localization in edge states, using the "gold standard'' for localization studies. Our system provides a new platform to investigate transport properties in the presence of synthetic gauge fields, which is important both from the fundamental perspective of studying photonic transport and for applications in classical and quantum information processing.

Mittal, S; Faez, S; Migdall, A; Taylor, J M; Hafezi, M

2014-01-01T23:59:59.000Z

351

Synthetic nanotubes lay foundation for new technology: Artificial pores  

NLE Websites -- All DOE Office Websites (Extended Search)

Synthetic nanotubes lay foundation for new technology: Artificial pores Synthetic nanotubes lay foundation for new technology: Artificial pores mimic key features of natural pores By Tona Kunz * July 17, 2012 Tweet EmailPrint Scientists have overcome key design hurdles to expand the potential uses of nanopores and nanotubes. The creation of smart nanotubes with selective mass transport opens up a wider range of applications for water purification, chemical separation and fighting disease. Nanopores and their rolled up version, nanotubes, consist of atoms bonded to each other in a hexagonal pattern to create an array of nanometer-scale openings or channels. This structure creates a filter that can be sized to select which molecules and ions pass into drinking water or into a cell. The same filter technique can limit the release of chemical by-products

352

Genomics and Systems Biology  

NLE Websites -- All DOE Office Websites (Extended Search)

Genomics and Systems Biology Genomics and Systems Biology Genomics and Systems Biology Los Alamos scientists perform research in functional genomics and structural genomics, and applications for such work cover diverse fields such as energy, agriculture, and environmental cleanup. Get Expertise Babetta Marrone Biofuels Program Manager Email Cheryl Kuske DOE BER Biological System Science Division Program Manager Email Chris Detter Emerging Threats Program Manager: Email Rebecca McDonald Bioscience Communications Email "We were asked to build a rocket ship," said developer Joel Berendzen, "but instead we built a 10,000 mph motorcycle." - Sequedex team LANL leads the world in computational finishing of microbial genomes Protein research Read caption + In 2013, Los Alamos scientist Richard Sayre and his team genetically

353

Thornridge Biology Home Page  

NLE Websites -- All DOE Office Websites (Extended Search)

How Do We Inherit Our Biological Characteristics How Do We Inherit Our Biological Characteristics How Do We Inherit Our Biological Characteristics? Shelly Peretz Science Department Chairperson Thornridge High School Office Phone: 708-225-4585 speretz@interaccess.com You are visitor Photograph taken from Genetic Pathology Gallery: Cytogenetics, University of Washington Medical Center. Be sure to submit the online sign-off each day. Introduction Individuals, families, health care providers and policymakers face important health care decisions every day. Today, with the growing awareness of the role that genetics plays in our society, decision-making requires more information than ever before. This project uses principles of biology to examine human genetics disorders. Students work in small groups (2-3) on projects which give them the opportunity to understand human

354

Work with Biological Materials  

NLE Websites -- All DOE Office Websites (Extended Search)

Work with Biological Materials Print Planning A complete Experiment Safety Sheet (ESS) is required before work can be done at the ALS. This ESS is either a part of the proposal...

355

Biological Interactions and Dynamics  

NLE Websites -- All DOE Office Websites (Extended Search)

PNNL-20717 Biological Interactions and Dynamics Science Theme Advisory Panel (BID-STAP) May 2011 Report: September 2011 Prepared for the U.S. Department of Energy's Office of...

356

Automation in biological crystallization  

Science Journals Connector (OSTI)

Automation is the response to overcoming the crystallization bottleneck in biological crystallography. This review provides a summary of the current methods and technologies applied in automated platforms for the setup of initial and follow-up crystallization experiments.

Shaw Stewart, P.

2014-05-28T23:59:59.000Z

357

Thermodynamics in biological systems  

Science Journals Connector (OSTI)

... An EMBO-sponsored Workshop on Thermodynamics in Biological Systems was held at the Villa Durazzo at Santa Margherita Ligure under the ... auspices of the University of Genoa on April 5?9, 1976.

A Correspondent

1976-05-27T23:59:59.000Z

358

A DNA Nanostructure Platform for Directed Assembly of Synthetic Vaccines  

Science Journals Connector (OSTI)

A DNA Nanostructure Platform for Directed Assembly of Synthetic Vaccines ... Here we report the design and synthesis of a 1,669-nucleotide, single-stranded DNA mol. ... These DL-DNAs induced greater amts. of tumor necrosis factor-? and interleukin-6 from RAW264.7 macrophage-like cells than did a mixt. of Y-DNA with the same sequences as the corresponding DL-DNA. ...

Xiaowei Liu; Yang Xu; Tao Yu; Craig Clifford; Yan Liu; Hao Yan; Yung Chang

2012-07-03T23:59:59.000Z

359

The stability and chemical modification of synthetically useful enzymes  

E-Print Network (OSTI)

THE STABILITY AND CHEMICAL MODIFICATION OF SYNTHETICALLY USEFUL ENZYMES A Thesis by GORDON LEE SMITH Submitted to the Graduate College of Texas A&M University in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE... May 1988 Major Subject: Chemistry THE STABILITY AND CHEMICAL MODIFICATION OF STATICALLY USEFUL ENZYMES A Thesis by GORDON LEE SMITH Approved as to style and content by: Chi-Huey ong (Chairman of Committee) A. Ian Scott (Member) B. J...

Smith, Gordon Lee

2012-06-07T23:59:59.000Z

360

Biological Control of Saltcedar  

E-Print Network (OSTI)

infesting the Pecos River has been treated recently with aerially applied herbicides. Plans are to expand this program to the Colorado River and other areas. Biological control can complement these herbicide programs, as the beetles can help suppress... saltcedar trees to justify the cost of aerial sprays. Cooperating agencies The Saltcedar Biological Control Program in Texas is a cooperative effort among many federal, state, public and private agencies and groups. The USDA-Agricultural Research Service...

Knutson, Allen E.; DeLoach, C. Jack; Muegge, Mark A.

2003-10-21T23:59:59.000Z

Note: This page contains sample records for the topic "organisms synthetic biology" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


361

Self-Organization, Embodiment, and Biologically Inspired Robotics  

Science Journals Connector (OSTI)

...addition to the thrust required to move forward, it is necessary to produce sufficient...generate adequate lift in the absence of any forward velocity. For instance, the shape...1416 ( 2007 ). 19 S. Hirose , E. F. Fukushima, Int. J. Robot. Res. 23 , 341...

Rolf Pfeifer; Max Lungarella; Fumiya Iida

2007-11-16T23:59:59.000Z

362

Nanoparticle Formation of Organic Compounds With Retained Biological Activity  

E-Print Network (OSTI)

of Pediatric, Radiology, Microbiology and Immunology, Stanford University School of Medicine, 318 Campus Drive

Zare, Richard N.

363

Synthetic Antimicrobial Oligomers Induce Composition-dependent Topological  

NLE Websites -- All DOE Office Websites (Extended Search)

Synthetic Antimicrobial Oligomers Induce Synthetic Antimicrobial Oligomers Induce Composition-dependent Topological Transition in Membranes The development of bacterial resistance to conventional antibiotics is a major public health concern. For example, methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE) and Staphylococcus aureus (VRSA) have emerged as common nosocomial (hospital-originating) infections. Circumvention of such resistance may be possi ble by emulating host defense antimicrobial peptides (AMP's), which are found in a broad range of species and have broad-spectrum antimicrobial properties. These AMP's have two structural motifs in common: they are cationic and amphipathic. It is thought that electro static interactions facilitate association of the peptide with the anionic bacterial membrane and amphiphilic interactions act to form pores in the bacterial membrane, leading to cell death. Thus, AMP's target generic characteristics common to the mem branes of many pathogenic species, and resistance to such natural defences evolves much more slowly than for conventional antibiotics. The exact molecular mechanisms by which membrane pores are formed are still not fully understood, although three major models ('barrel-stave', 'toroidal pore', 'carpet') have been proposed. Moreover, these models do not ex haustively cover all possibilities, as AMP activity is not always correlated with the loss of a permeability barrier. Understanding the structural tenden cies generated in antimicrobial-membrane interactions is an essential step to elucidating such molecular mechanisms and therefore to the pre dictive design of synthetic AMP analogs.

364

Better practices and synthetic fluid improve drilling rates  

SciTech Connect

Improved drilling practices, combined with the use of olefin-based synthetic drilling fluids, have dramatically reduced drilling time and costs in a difficult drilling area in the Gulf of Mexico. In the South Pass area, Marathon Oil Co. and other operators have had wells with long drilling times and high costs. In addition to the two wells with record penetration rates, routine drilling rates have also increased from the use of synthetic mud and careful drilling practices. Through application of these improved drilling practices, 2,000--3,000 ft/day can be drilled routinely. Marathon achieves this goal by applying the experience gained on previous wells, properly training and involving the crews, and using innovative drilling systems. Improved drilling practices and systems are just one part of successful, efficient drilling. Rig site personnel are major contributors to safely and successfully drilling at high penetration rates for extended periods. The on site personnel must act as a team and have the confidence and proper mental attitude about what is going on downhole. The paper describes the drilling history in the South Pass area, the synthetic drilling fluid used, cuttings handling, hole cleaning, drilling practices, bottom hole assemblies, and lost circulation.

White, W. (Marathon Oil Co., Lafayette, LA (United States)); McLean, A.; Park, S. (M-I Drilling Fluids, Houston, TX (United States))

1995-02-20T23:59:59.000Z

365

Formulation of soluble oils with synthetic and petroleum sulfonates  

SciTech Connect

Metalworking fluids for metal removal are formulated to provide cooling, lubrication, and rust protection when cutting and machining metals. There are basically four types of cutting fluids: straight oils, synthetics, semisynthetic fluids and soluble oils. The last type is the most widely used for metal removal operations such as cutting, drilling and grinding. Soluble oils used for metalworking operations are normally the oil-in-water type, with oil as the internal phase and water as the external phase. The soluble oils can have rather complex compositions, usually containing two or more emulsifiers and coupling agents, as well as additives to provide rust inhibition, lubricity, detergency, resistance to bacterial attack and foam control. The dominant emulsifier in a soluble oil is usually sodium sulfonate which also has the secondary benefit of being a rust inhibitor. Soluble oil emulsions based on petroleum or synthetic sulfonates have been found to improve lubrication and cleaning of metal parts and equipment. As has been done previously, a series of emulsification studies were conducted using petroleum and synthetic sulfonates. Emulsifier level, coemulsifiers and minor formulation adjustments were made to optimize each system. This study was made using naphthenic oil basestock. Formulations were evaluated using criteria including concentrate stability, hard and soft water emulsion stability, emulsibility, foaming tendency and response to defoamers, antirust properties and cost effectiveness of individual formulations. The results of these evaluations are presented in the present paper.

Eckard, A.; Riff, I.; Weaver, J. [Witco Corp., Oakland, NJ (United States)

1997-06-01T23:59:59.000Z

366

Method for producing and regenerating a synthetic CO[sub 2] acceptor  

DOE Patents (OSTI)

A method is described for producing a synthetic CO[sub 2] acceptor by feeding a mixture of finely divided silica and at least one finely divided calcium compound selected from the group consisting of calcium oxide and calcium carbonate to a fluidized bed; operating the fluidized bed at suitable conditions to produce pellets of synthetic CO[sub 2] acceptor and recovering the pellets of synthetic CO[sub 2] acceptor from the fluidized bed. Optionally, spent synthetic CO[sub 2] acceptor can be charged to the fluidized bed to produce regenerated pellets of synthetic CO[sub 2] acceptor. 1 fig.

Lancet, M. S.; Curran, G. P.; Gorin, E.

1982-05-18T23:59:59.000Z

367

Method for producing and regenerating a synthetic CO.sub.2 acceptor  

DOE Patents (OSTI)

A method for producing a synthetic CO.sub.2 acceptor by feeding a mixture of finely divided silica and at least one finely divided calcium compound selected from the group consisting of calcium oxide and calcium carbonate to a fluidized bed; operating the fluidized bed at suitable conditions to produce pellets of synthetic CO.sub.2 acceptor and recovering the pellets of synthetic CO.sub.2 acceptor from the fluidized bed. Optionally, spent synthetic CO.sub.2 acceptor can be charged to the fluidized bed to produce regenerated pellets of synthetic CO.sub.2 acceptor.

Lancet, Michael S. (Pittsburgh, PA); Curran, George P. (Pittsburgh, PA); Gorin, Everett (San Rafael, CA)

1982-01-01T23:59:59.000Z

368

Report of The Structural Biology Subcommittee of The Biological and  

Office of Science (SC) Website

Report of The Structural Biology Subcommittee of The Report of The Structural Biology Subcommittee of The Biological and Environmental Research Advisory Committee Biological and Environmental Research Advisory Committee (BERAC) BERAC Home Meetings Members Charges/Reports Current BERAC Charges Archive of BERAC Reports Charter .pdf file (40KB) BER Committees of Visitors BER Home Charges/Reports Report of The Structural Biology Subcommittee of The Biological and Environmental Research Advisory Committee Print Text Size: A A A RSS Feeds FeedbackShare Page REPORT of the STRUCTURAL BIOLOGY SUBCOMMITTEE of the BIOLOGICAL AND ENVIRONMENTAL RESEARCH ADVISORY COMMITTEE In response to the charge letter of Dr. Martha Krebs, May 28, 1998 Executive Summary Structural biology and especially macromolecular crystallography are playing an increasingly important role in biological discoveries. In order

369

Structural biology research at the National Synchroton Light Source  

SciTech Connect

The world`s foremost facility for scientific research using x-rays and ultraviolet and infrared radiation is operated by the national synchrotron Light Source Department. This year alone, a total of 2200 guest researchers performed experiments at the world`s largest source of synchrotron light. Researchers are trying to define the three- dimensional structures of biological macromolecules to create a map of life, a guide for exploring the biological and chemical interactions of the vast variety of molecules found in living organisms. Studies in structural biology may lead to new insights into how biological systems are formed and nourished, how they survive and grow, how they are damaged and die. This document discusses some the the structural biological research done at the National Synchrotron Light Source.

NONE

1996-05-01T23:59:59.000Z

370

California: Breakthrough in Algae Biology  

Office of Energy Efficiency and Renewable Energy (EERE)

Breakthrough in algae biology will have a significant impact in the economics of algal biofuel production.

371

Complex biological and bio-inspired systems  

SciTech Connect

The understanding and characterization ofthe fundamental processes of the function of biological systems underpins many of the important challenges facing American society, from the pathology of infectious disease and the efficacy ofvaccines, to the development of materials that mimic biological functionality and deliver exceptional and novel structural and dynamic properties. These problems are fundamentally complex, involving many interacting components and poorly understood bio-chemical kinetics. We use the basic science of statistical physics, kinetic theory, cellular bio-chemistry, soft-matter physics, and information science to develop cell level models and explore the use ofbiomimetic materials. This project seeks to determine how cell level processes, such as response to mechanical stresses, chemical constituents and related gradients, and other cell signaling mechanisms, integrate and combine to create a functioning organism. The research focuses on the basic physical processes that take place at different levels ofthe biological organism: the basic role of molecular and chemical interactions are investigated, the dynamics of the DNA-molecule and its phylogenetic role are examined and the regulatory networks of complex biochemical processes are modeled. These efforts may lead to early warning algorithms ofpathogen outbreaks, new bio-sensors to detect hazards from pathomic viruses to chemical contaminants. Other potential applications include the development of efficient bio-fuel alternative-energy processes and the exploration ofnovel materials for energy usages. Finally, we use the notion of 'coarse-graining,' which is a method for averaging over less important degrees of freedom to develop computational models to predict cell function and systems-level response to disease, chemical stress, or biological pathomic agents. This project supports Energy Security, Threat Reduction, and the missions of the DOE Office of Science through its efforts to accurately model biological systems at the molecular and cellular level. The project's impact encompasses applications to biofuels, to novel sensors and to materials with broad use for energy or threat reduction. The broad, interdisciplinary approach of CNLS offers the unparalleled strength of combining science backgrounds and expertise -a unique and important asset in attacking the complex science of biological organisms. This approach also allows crossfertilization, with concepts and techniques transferring across field boundaries.

Ecke, Robert E [Los Alamos National Laboratory

2009-01-01T23:59:59.000Z

372

Deep oxidation of glucose in enzymatic fuel cells through a synthetic enzymatic pathway containing a cascade of two thermostable dehydrogenases  

NLE Websites -- All DOE Office Websites (Extended Search)

Deep Deep oxidation of glucose in enzymatic fuel cells through a synthetic enzymatic pathway containing a cascade of two thermostable dehydrogenases Zhiguang Zhu a , Fangfang Sun a , Xiaozhou Zhang a,d , Y.-H. Percival Zhang a,b,c,d,n a Biological Systems Engineering Department, Virginia Polytechnic Institute and State University (Virginia Tech), 210-A Seitz Hall, Blacksburg, Virginia 24061, USA b Institute for Critical Technology and Applied Science (ICTAS), Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061, USA c DOE BioEnergy Science Center (BESC), Oak Ridge, Tennessee 37831, USA d Gate Fuels Inc., 2200 Kraft Drive, Suite 1200B, Blacksburg, VA 24060, USA a r t i c l e i n f o Article history: Received 12 January 2012 Received in revised form 26 March 2012 Accepted 4 April 2012 Keywords: Deep oxidation Enzymatic fuel cell Glucose biobattery Thermoenzyme

373

A Synthetic Substrate of DNA Polymerase Deviating from the Bases, Sugar, and Leaving Group of Canonical Deoxynucleoside Triphosphates  

Science Journals Connector (OSTI)

Summary The selection of artificial nucleic acids to be used for synthetic biology purposes is based on their structural and biochemical orthogonality to the natural system. We describe the example of a nucleotide mimic that functions as a substrate for polymerases and in which the carbohydrate moiety as well as the base moiety and the leaving group are different from that of the natural building blocks. The nucleotides themselves have two anomeric centers, and different leaving group properties of substituents at both anomeric centers need to be exploited to perform selective glycosylation reactions for their synthesis. In addition, the reversibility of the polymerase reaction at the level of the template has been demonstrated when pyrophosphate functions as leaving group and not with the alternative leaving groups.

Mi-Yeon Jang; Xiao-Ping Song; Mathy Froeyen; Philippe Marlière; Eveline Lescrinier; Jef Rozenski; Piet Herdewijn

2013-01-01T23:59:59.000Z

374

Report of the Structural Biology Subcommittee of the Biological and  

Office of Science (SC) Website

Report of the Structural Biology Subcommittee of the Report of the Structural Biology Subcommittee of the Biological and Environmental Research Advisory Committee Biological and Environmental Research Advisory Committee (BERAC) BERAC Home Meetings Members Charges/Reports Current BERAC Charges Archive of BERAC Reports Charter .pdf file (40KB) BER Committees of Visitors BER Home Charges/Reports Report of the Structural Biology Subcommittee of the Biological and Environmental Research Advisory Committee Print Text Size: A A A RSS Feeds FeedbackShare Page REPORT of the STRUCTURAL BIOLOGY SUBCOMMITTEE of the BIOLOGICAL AND ENVIRONMENTAL RESEARCH ADVISORY COMMITTEE In response to the charge letter of Dr. Martha Krebs, June 10, 1997 Executive Summary Six years have elapsed since the previous report of the Structural Biology Subcommittee. Dramatic progress and advances in the field over this period

375

Automating the purification and isolation of synthetic DNA  

SciTech Connect

The authors describe the application of robotics to the purification and isolation of synthetic oligodeoxyribunucleotides. Starting with commercially available components, they have designed and programmed a robot based system that can isolate oligonucleotides from polyacrylamide gel slices, prepare oligonucleotides for purification by polyacrylamide gel electrophoresis and execute a rapid purification protocol on a disposable C-18 reverse phase column. Each operation has been fully automated, including evaporative centrifugation, such that the system can execute any two procedures simultaneously with a throughput of 12 samples in about six hours.

Jones, S.S.; Brown, J.E.; Vanstone, D.A.; Stone, D.K.; Brown, E.L.

1987-01-01T23:59:59.000Z

376

Fate of Mercury in Synthetic Gypsum Used for Wallboard Production  

SciTech Connect

This report presents and discusses results from the project 'Fate of Mercury in Synthetic Gypsum Used for Wallboard Production', performed at five different full-scale commercial wallboard plants. Synthetic gypsum produced by wet flue gas desulfurization (FGD) systems on coal-fired power plants is commonly used in the manufacture of wallboard. This practice has long benefited the environment by recycling the FGD gypsum byproduct, which is becoming available in increasing quantities, decreasing the need to landfill this material, and increasing the sustainable design of the wallboard product. However, new concerns have arisen as recent mercury control strategies involve the capture of mercury in FGD systems. The objective of this study has been to determine whether any mercury is released into the atmosphere at wallboard manufacturing plants when the synthetic gypsum material is used as a feedstock for wallboard production. The project has been co-funded by the U.S. DOE National Energy Technology Laboratory (Cooperative Agreement DE-FC26-04NT42080), USG Corporation, and EPRI. USG Corporation is the prime contractor, and URS Group is a subcontractor. The project scope included seven discrete tasks, each including a test conducted at various USG wallboard plants using synthetic gypsum from different wet FGD systems. The project was originally composed of five tasks, which were to include (1) a base-case test, then variations representing differing power plant: (2) emissions control configurations, (3) treatment of fine gypsum particles, (4) coal types, and (5) FGD reagent types. However, Task 5,could not be conducted as planned and instead was conducted at conditions similar to Task 3. Subsequently an opportunity arose to test gypsum produced from the Task 5 FGD system, but with an additive expected to impact the stability of mercury, so Task 6 was added to the project. Finally, Task 7 was added to evaluate synthetic gypsum produced at a power plant from an additional coal type. In the project, process stacks in the wallboard plant were sampled using the Ontario Hydro method. In every task, the stack locations sampled included a gypsum dryer and a gypsum calciner. In Tasks 1 and 4 through 7, the stack of the dryer for the wet wallboard product was also tested. Also at each site, in-stream process samples were collected and analyzed for mercury concentration before and after each significant step in wallboard production. These results and process data were used to construct mercury mass balances across the wallboard plants. The results from the project showed a wide range of percentage mercury losses from the synthetic gypsum feedstocks as measured by the Ontario Hydro method at the process stacks, ranging from 2% to 55% of the mercury in the gypsum feedstock. For the tasks exceeding 10% mercury loss across the wallboard plant, most of the loss occurred across the gypsum calciner. When total wallboard emissions remained below 10%, the primary emission location varied with a much less pronounced difference in emission between the gypsum dryer, calciner and board dryer. For all seven tasks, the majority of the mercury emissions were measured to be in the elemental form (Hg{sup 0}). Overall, the measured mercury loss mass rates ranged from 0.01 to 0.17 grams of mercury per dry ton of synthetic gypsum processed, or 0.01 to 0.4 pounds of mercury released per million square feet of wallboard produced from synthetic gypsum. The Coal Combustion Product Production and Use Survey from the American Coal Ash Association (ACAA) indicate that 7,579,187 short tons of synthetic gypsum were used for wallboard production in 2006. Extrapolating the results of this study to the ACAA industry usage rate, we estimate that mercury releases from wallboard production plants in 2006 ranged between 150 to 3000 pounds for the entire U.S. wallboard industry. With only seven sets of wallboard plant measurements, it is difficult to draw firm conclusions about what variables impact the mercury loss percentages across the wallboard plants. One significant o

Jessica Sanderson

2007-12-31T23:59:59.000Z

377

Frequency domain computation of synthetic vertical seismic profiles  

E-Print Network (OSTI)

, and the artifacts in the time function. The algorithm fails when the total attenuation xfx/Qv is so large that underflow occurs. For this model and multi-precision computation the failure point of the algorithm occurs when sfx/Qv is about 30. Synthetic VSPs were... in Figure 6c. The relative amplitude between events Al and A2 at interface 1 has been checked against the theoretical expression: Amp(A2)/Amp(A') = [(r /r )-r r ]exp[ (~f0/Qv)2x] = -1. 2693 exp(-0. 050265f ). 0 (28) This formula is the exact expression...

Wu, Ru-Chuan

2012-06-07T23:59:59.000Z

378

Institute for Multiscale Modeling of Biological Interactions  

SciTech Connect

The Institute for Multiscale Modeling of Biological Interactions (IMMBI) has two primary goals: Foster interdisciplinary collaborations among faculty and their research laboratories that will lead to novel applications of multiscale simulation and modeling methods in the biological sciences and engineering; and Building on the unique biophysical/biology-based engineering foundations of the participating faculty, train scientists and engineers to apply computational methods that collectively span multiple time and length scales of biological organization. The success of IMMBI will be defined by the following: Size and quality of the applicant pool for pre-doctoral and post-doctoral fellows; Academic performance; Quality of the pre-doctoral and post-doctoral research; Impact of the research broadly and to the DOE (ASCR program) mission; Distinction of the next career step for pre-doctoral and post-doctoral fellows; and Faculty collaborations that result from IMMBI activities. Specific details about accomplishments during the three years of DOE support for IMMBI have been documented in Annual Progress Reports (April 2005, June 2006, and March 2007) and a Report for a National Academy of Sciences Review (October 2005) that were submitted to DOE on the dates indicated. An overview of these accomplishments is provided.

Michael E. Paulaitis

2009-12-26T23:59:59.000Z

379

Biological effectiveness of neutrons: Research needs  

SciTech Connect

The goal of this report was to provide a conceptual plan for a research program that would provide a basis for determining more precisely the biological effectiveness of neutron radiation with emphasis on endpoints relevant to the protection of human health. This report presents the findings of the experts for seven particular categories of scientific information on neutron biological effectiveness. Chapter 2 examines the radiobiological mechanisms underlying the assumptions used to estimate human risk from neutrons and other radiations. Chapter 3 discusses the qualitative and quantitative models used to organize and evaluate experimental observations and to provide extrapolations where direct observations cannot be made. Chapter 4 discusses the physical principles governing the interaction of radiation with biological systems and the importance of accurate dosimetry in evaluating radiation risk and reducing the uncertainty in the biological data. Chapter 5 deals with the chemical and molecular changes underlying cellular responses and the LET dependence of these changes. Chapter 6, in turn, discusses those cellular and genetic changes which lead to mutation or neoplastic transformation. Chapters 7 and 8 examine deterministic and stochastic effects, respectively, and the data required for the prediction of such effects at different organizational levels and for the extrapolation from experimental results in animals to risks for man. Gaps and uncertainties in this data are examined relative to data required for establishing radiation protection standards for neutrons and procedures for the effective and safe use of neutron and other high-LET radiation therapy.

Casarett, G.W.; Braby, L.A.; Broerse, J.J.; Elkind, M.M.; Goodhead, D.T.; Oleinick, N.L.

1994-02-01T23:59:59.000Z

380

Environmental Sciences, Fisheries, Forestry & Wildlife Biology Organizations Hiring Students in Environmental Sciences, Fisheries, Forestry & Wildlife Biology  

E-Print Network (OSTI)

Electric & Gas Signal Event Group Softbank Stanley Eisenman Shoes Table Rock State Park Terracon, Inc Research Station USGS Veolia WCS Environmental Ltd. West End Deer Ranch Wildfire Defense Systems Wilson Oil of Illinois University of Manitoba University of Michigan University of Missouri-Columbia University of North

Note: This page contains sample records for the topic "organisms synthetic biology" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


381

Environmental Sciences, Fisheries, Forestry & Wildlife Biology Organizations Hiring Students in Environmental Sciences, Fisheries, Forestry & Wildlife Biology  

E-Print Network (OSTI)

Wildfire Defense System Wolf Tree, Inc. Yellow Jackets Further Education Colorado State University Cornell of Maplewood Clemson University Youth Learning Institute Colorado Mosquito Control Colorado Natural Heritage Program Colorado Parks and Wildlife Colorado State Forest Service Colorado State University Columbian Park

382

Biology of Borrelia species.  

Science Journals Connector (OSTI)

...biology of this genus and, to some extent, acquaint investi- gators of this generation with the large body of works of past generations...taxonomy. Another phenotype that was judged by previous investi- gators to be important for any classification scheme for borreliae...

A G Barbour; S F Hayes

1986-12-01T23:59:59.000Z

383

CANCER BIOLOGY Infectioustumourcells  

E-Print Network (OSTI)

CANCER BIOLOGY Infectioustumourcells David Dingli and Martin A. Nowak Cancer cells are generally infectious agents and be transmitted between individuals. The current view of cancer development is that normal cells are transformed into tumour cells by sequential mutations that activate cancer- promoting

Nowak, Martin A.

384

Journal of Theoretical Biology ] (  

E-Print Network (OSTI)

, and Uganda as of September 14, 2003 (CDC, 2003b; WHO, 2003a). Two different strains of the Ebola virus (Ebola-Zaire and the Ebola-Sudan) have been reported in those regions. Despite extensive search, the reservoir of the EbolaJournal of Theoretical Biology ] (

Chowell, Gerardo

385

Fish Biology Introduction  

E-Print Network (OSTI)

Lab 10: Fish Biology Introduction The effective management of fish populations requires knowledge of the growth rate of the fish. This requires determination of the age of fish to develop a relationship between the size and age of fish. For an inventory, this information provides insights to evaluate the potential

Jochem, Frank J.

386

Evolutionary biology of language  

Science Journals Connector (OSTI)

...Support, Non-U.S. Gov't Review | Animals Biological Evolution...exchange information, make plans, express new ideas and totally...their pay-o . This is the standard assumption of evolu- tionary...Eigen & Schuster 1979). Standard quasispecies theory has constant...

2000-01-01T23:59:59.000Z

387

Probabilistic Biological Network Alignment  

Science Journals Connector (OSTI)

Interactions between molecules are probabilistic events. An interaction may or may not happen with some probability, depending on a variety of factors such as the size, abundance, or proximity of the interacting molecules. In this paper, we consider ... Keywords: Probabilistic logic,Proteins,Network topology,Polynomials,Random variables,Topology,random graphs,Probabilistic biological networks,network alignment,neighborhood topology

Andrei Todor; Alin Dobra; Tamer Kahveci

2013-01-01T23:59:59.000Z

388

Work for Biology Teachers  

Science Journals Connector (OSTI)

... material devised for the A-level trials has crystallized out into a modest set of interrelated books and it is only regrettable that all could not have become available simultaneously because ... gain information for themselves and, in doing so, to get some understanding of the processes whereby biological knowledge is acquired. Each set of investigations is preceded by an explanatory ...

JOYCE VINNICOMBE

1970-11-07T23:59:59.000Z

389

Thermodynamics of Biological Synthesis  

Science Journals Connector (OSTI)

... SEVERAL selected topics of thermodynamics are of importance for the interpretation of the results of biochemical experiments. A closer ... ago there were still lively disputes among eminent scientists as to whether the laws of thermodynamics are strictly applicable to biological systems. Some suggested that evolution or man's intellect ...

HERBERT GUTFREUND

1957-08-03T23:59:59.000Z

390

ECOLOGY LABORATORY BIOLOGY 341  

E-Print Network (OSTI)

Page 1 ECOLOGY LABORATORY BIOLOGY 341 Fall Semester 2008 Bighorn Sheep Rams at Bison Range National ecological data; and 3) oral and written communication skills. Thus, these ecology labs, and statistical analyses appropriate for ecological data. A major goal of this class will be for you to gain

Vonessen, Nikolaus

391

BIOLOGY AND AQUATIC PLANTS  

E-Print Network (OSTI)

Handbook First published in the United States of America in 2009 by Aquatic Ecosystem Restoration plant management. The Aquatic Ecosystem Restoration Foundation (AERF) is pleased to bring you Biology for the environmentally and scientifically sound management, conservation and restoration of aquatic ecosystems. One

Jawitz, James W.

392

Organic removal from domestic wastewater by activated alumina adsorption  

E-Print Network (OSTI)

of the major groups of pollutants in wastewaters. Adsorption by granular activated carbon, a non-polar adsorbent, is now the primary treatment process for removal of residual organics from biologically treated wastewater. The ability of activated alumina..., which is a polar adsorbent, to remove total organic carbon (TOC) and some trace organics from domestic wastewater has been evaluated. Batch adsorption experiments were used to investigate the effect of pH and total dissolved solids on activated...

Yang, Pe-Der

2012-06-07T23:59:59.000Z

393

A comparison of spotlight synthetic aperture radar image formation techniques  

SciTech Connect

Spotlight synthetic aperture radar images can be formed from the complex phase history data using two main techniques: (1) polar-to-cartesian interpolation followed by two-dimensional inverse Fourier transform (2DFFT), and (2) convolution backprojection (CBP). CBP has been widely used to reconstruct medical images in computer aided tomography, and only recently has been applied to form synthetic aperture radar imagery. It is alleged that CBP yields higher quality images because (1) all the Fourier data are used and (2) the polar formatted data is used directly to form a 2D Cartesian image and therefore 2D interpolation is not required. This report compares the quality of images formed by CBP and several modified versions of the 2DFFT method. We show from an image quality point of view that CBP is equivalent to first windowing the phase history data and then interpolating to an exscribed rectangle. From a mathematical perspective, we should expect this conclusion since the same Fourier data are used to form the SAR image. We next address the issue of parallel implementation of each algorithm. We dispute previous claims that CBP is more readily parallelizable than the 2DFFT method. Our conclusions are supported by comparing execution times between massively parallel implementations of both algorithms, showing that both experience similar decreases in computation time, but that CBP takes significantly longer to form an image.

Knittle, C.D.; Doren, N.E.; Jakowatz, C.V.

1996-10-01T23:59:59.000Z

394

Spatially Interpolated Nonlinear Anodization in Synthetic Aperture Radar Imagery  

SciTech Connect

Spatially Interpolated Nonlinear Anodization in Synthetic Aperture Original formulation of spatially variant anodization for complex synthetic aperture radar (SAR) imagery oversampled at twice the Nyquist rate (2.OX). Here we report a spatially interpolating, noninteger-oversampled SVA sidelobe. The pixel's apparent IPR location is assessed by comparing its value to the sum of its value plus weighted comparable for exact interpolation. However, exact interpolation implies an ideal sine interpolator3 and large components may not be necessary. Note that P is the summation of IPR diagonal values. The value of a sine IPR on the diagonals is a sine-squared; values much less than cardinal direction (m, n) values. This implies that cardinal direction interpolation requires higher precision than diagonal interpolation. Consequently, we employed a smaller set. The spatially interpolated SVA used an 8-point/4-point sine interpolator described above. Table 1 shows the Table 1 results show a two-times speed-up using the 1.3x oversampled and spatially interpolated SVA over the Figure 1d. Detected results of 1.3x oversampled sine interpolated spatially variant

Eichel, Paul H.; Jakowatz, Jr., Charles V.; Yocky, David A.

1999-06-29T23:59:59.000Z

395

Synthetic Generation of Social Network Data With Endorsements  

E-Print Network (OSTI)

In many simulation studies involving networks there is the need to rely on a sample network to perform the simulation experiments. In many cases, real network data is not available due to privacy concerns. In that case we can recourse to synthetic data sets with similar properties to the real data. In this paper we discuss the problem of generating synthetic data sets for a certain kind of online social network, for simulation purposes. Some popular online social networks, such as LinkedIn and ResearchGate, allow user endorsements for specific skills. For each particular skill, the endorsements give rise to a directed subgraph of the corresponding network, where the nodes correspond to network members or users, and the arcs represent endorsement relations. Modelling these endorsement digraphs can be done by formulating an optimization problem, which is amenable to different heuristics. Our construction method consists of two stages: The first one simulates the growth of the network, and the second one solves ...

Pérez-Rosés, Hebert

2014-01-01T23:59:59.000Z

396

Structural Molecular Biology, SSRL  

NLE Websites -- All DOE Office Websites (Extended Search)

of tRNA synthetase in organisms. Structure of the DUF2233 Domain in Bacteria and the Stuttering-associated UCE Glycoprotein UCE plays a key role in the functioning of lysosomes,...

397

Biological constraints on habitability  

Science Journals Connector (OSTI)

......the high concentration of dissolved salts as the surrounding seawater freezes, and thin films of water remain fluid around mineral...standard laboratory procedure for preserving microbial samples for storage. Radiation Radiation that affects the survival of organisms......

Lewis Dartnell

2011-02-01T23:59:59.000Z

398

The significance of chemical and biological warfare for the people  

Science Journals Connector (OSTI)

...the only living organisms that presently can be used in the warheads of biological weapons. The diseases produced by these agents...as a vapor, and can kill when absorbed through the eyes or intact skin. Mustard is an irritating liquid blister-agent (vesicant...

I L Bennett; Jr

1970-01-01T23:59:59.000Z

399

Fuzzy predictive control for nitrogen removal in biological wastewater treatment  

E-Print Network (OSTI)

Fuzzy predictive control for nitrogen removal in biological wastewater treatment S. Marsili wastewater is too low, full denitrification is difficult to obtain and an additional source of organic carbon predictive control; wastewater treatment plant Introduction The problem of improving the nitrogen removal

400

Steven J. Schwager Department of Biological Statistics and Computational Biology  

E-Print Network (OSTI)

BTRY 3010, Biological Statistics I BTRY 4080 (408), Theory of Probability BTRY 4090 (409), Theory of Multivariate Normal Outliers. (1982) Ann. Statist. 10:943-954. (with B.H. Margolin) 2. Run ProbabilitiesSteven J. Schwager Department of Biological Statistics and Computational Biology and Department

Keinan, Alon

Note: This page contains sample records for the topic "organisms synthetic biology" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


401

ORGANIC CHEMISTRY UCLA Organic Chemistry Faculty  

E-Print Network (OSTI)

ORGANIC CHEMISTRY UCLA Organic Chemistry Faculty perform research in molecular machines, exotic CHEMISTRY FACULTY RESEARCH INTERESTS Anne M. Andrews, Professor-in-Residence: Understanding how areas of interest include cross- coupling reactions, green chemistry, heterocycle synthesis, and natural

Levine, Alex J.

402

Low Dose Radiation Program: Radiation Biology and the Radiation Research  

NLE Websites -- All DOE Office Websites (Extended Search)

Biology and the Radiation Research Program Biology and the Radiation Research Program The Department of Energy (DOE) and its predecessor organizations, Energy Research and Development Agency (ERDA) and Atomic Energy Commission (AEC), always have been concerned about the health effects of ionizing radiation. Extensive research has been conducted under their sponsorship at all levels of biological organization from molecules to man. Over the past 60 years, studies using every type of radiation source have included exposure to both external radiation sources and to internally deposited radioactive materials. These exposures used different dose patterns and distributions delivered over a wide range of experimental times. This extensive research provided the basis for the new Low Dose Radiation Research Program, linking

403

Phosphate and Organic Acids as Competing Sorbates on Amorphous Aluminum Oxide. (3791)  

E-Print Network (OSTI)

Phosphate and Organic Acids as Competing Sorbates on Amorphous Aluminum Oxide. (3791) Authors: K sorption of P to amorphous aluminum oxides. Alum initially decreases litter pH, so the stability of P was employed to investigate the adsorption of phosphate and oxalate, to synthetic amorphous aluminum hydroxide

Sparks, Donald L.

404

2007 Archaea: Ecology, Metabolism and Molecular Biology  

SciTech Connect

The Archaea are a fascinating and diverse group of prokaryotic organisms with deep roots overlapping those of eukaryotes. The focus of this GRC conference, 'Archaea: Ecology Metabolism & Molecular Biology', expands on a number of emerging topics highlighting the evolution and composition of microbial communities and novel archaeal species, their impact on the environment, archaeal metabolism, and research that stems from sequence analysis of archaeal genomes. The strength of this conference lies in its ability to couple reputable areas with new scientific topics in an atmosphere of stimulating exchange. This conference remains an excellent opportunity for younger scientists to interact with world experts in this field.

Imke Schroeder

2008-09-18T23:59:59.000Z

405

Synthesis, Structure, and Photochemistry of Exceptionally Stable Synthetic DNA Hairpins with Stilbene Diether Linkers  

Science Journals Connector (OSTI)

Synthesis, Structure, and Photochemistry of Exceptionally Stable Synthetic DNA Hairpins with Stilbene Diether Linkers ... Bis(oligonucleotide) conjugates with synthetic linkers connecting short complementary oligonucleotides are known to form synthetic DNA or RNA hairpins which are, in some cases, more stable than natural hairpins possessing nucleotide linkers.1 Letsinger and Wu2 reported the use of a stilbenedicarboxamide (Sa, Chart 1) linker which formed stable hairpin structures possessing as few as three T:A or two G:C base pairs. ... The ability of the Sa linker to serve as an electron acceptor has been exploited in our studies of hole injection and migration processes in synthetic DNA hairpins. ...

Frederick D. Lewis; Yansheng Wu; Xiaoyang Liu

2002-09-21T23:59:59.000Z

406

E-Print Network 3.0 - atp synthetic flux Sample Search Results  

NLE Websites -- All DOE Office Websites (Extended Search)

flux Search Powered by Explorit Topic List Advanced Search Sample search results for: atp synthetic flux Page: << < 1 2 3 4 5 > >> 1 A genetically encoded fluorescent reporter...

407

Feasibility of Steam Hydrogasification of Microalgae for Production of Synthetic Fuels  

E-Print Network (OSTI)

Gasifier Intermediate products Low Energy Gas Final product Power Steam Gas Synthetic Liquids Spark and diesel engines Process Heat & Power Medium &

Suemanotham, Amornrat

2014-01-01T23:59:59.000Z

408

Use of Waste Materials from the Production of Synthetic Rubber for Preparing Aluminosilicate Ceramics  

Science Journals Connector (OSTI)

An aluminum-silicon-chromium powder (ASC) extracted from waste gases in synthetic rubber production is used as an addition to kaolin-...

V. N. Antsiferov; T. S. Golodnova; S. E. Porozova…

2002-09-01T23:59:59.000Z

409

A new technology for producing synthetic liquid hydrocarbons from gaseous hydrocarbons  

Science Journals Connector (OSTI)

Conventional technologies of synthetic liquid fuels (SLF) production from gaseous hydrocarbons by producing synthesis ... liquid hydrocarbons are examined. A high-efficiency SLF production technology that allows ...

D. L. Astanovskii; L. Z. Astanovskii; A. L. Lapidus

2012-09-01T23:59:59.000Z

410

Oxygen as a control on seafloor biological communities and their roles in sedimentary carbon cycling  

E-Print Network (OSTI)

Oxygen as a control on seafloor biological communities and their roles in sedimentary carbon experiments were conducted at sites spanning the steep oxygen, organic matter, and biological community gradients across the Arabian Sea oxygen minimum zone, in order to quantify the role that fauna play

411

Fate of Mercury in Synthetic Gypsum Used for Wallboard Production  

SciTech Connect

This report presents and discusses results from Task 6 of the study 'Fate of Mercury in Synthetic Gypsum Used for Wallboard Production,' performed at a full-scale commercial wallboard plant. Synthetic gypsum produced by wet flue gas desulfurization (FGD) systems on coal-fired power plants is commonly used in the manufacture of wallboard. This practice has long benefited the environment by recycling the FGD gypsum byproduct, which is becoming available in increasing quantities, decreasing the need to landfill this material, and increasing the sustainable design of the wallboard product. However, new concerns have arisen as recent mercury control strategies involve the capture of mercury in FGD systems. The objective of this study is to determine whether any mercury is released into the atmosphere when the synthetic gypsum material is used as a feedstock for wallboard production. The project is being co-funded by the U.S. DOE National Energy Technology Laboratory (Cooperative Agreement DE-FC26-04NT42080), USG Corporation, and EPRI. USG Corporation is the prime contractor, and URS Group is a subcontractor. The project scope now includes six discrete tasks, each conducted at various USG wallboard plants using synthetic gypsum from different FGD systems. The project was originally composed of five tasks, which were to include (1) a baseline test, then variations representing differing power plant: (2) emissions control configurations, (3) treatment of fine gypsum particles, (4) coal types, and (5) FGD reagent types. However, Task 5, which was to include testing with an alternate FGD reagent, could not be conducted as planned. Instead, Task 5 was conducted at conditions similar to Task 3, although with gypsum from an alternate FGD system. Subsequent to conducting Task 5 under these revised conditions, an opportunity arose to test gypsum produced at the same FGD system, but with an additive (Degussa Corporation's TMT-15) being used in the FGD system. TMT-15 was expected to impact the stability of mercury in synthetic gypsum used to produce wallboard, so Task 6 was added to the project to test this theory. In this project, process stacks in the wallboard plant have been sampled using the Ontario Hydro method. For every task, the stack locations sampled have included a dryer for the wet gypsum as it enters the plant and a gypsum calciner. For Tasks 1, 4, 5 and 6, the stack of the dryer for the wet wallboard product was also tested. Also at each site, in-stream process samples were collected and analyzed for mercury concentration before and after each significant step in wallboard production. The Ontario Hydro results, process sample mercury concentration data, and process data were used to construct mercury mass balances across the wallboard plants. Task 6 was conducted at a wallboard plant processing synthetic gypsum from a power plant that fires Eastern bituminous coal. The power plant has a single-loop, open spray tower limestone forced oxidation FGD system, with the forced oxidation conducted in the reaction tank integral with the FGD absorber. The FGD system has gypsum fines blow down as part of the dewatering step. The power plant is equipped with a selective catalytic reduction (SCR) system for NOX emissions control, and the SCR was in service during the time period the gypsum tested was produced. Also, as mentioned above, Degussa additive TMT-15 was being added to the FGD system when this gypsum was produced. The results of the Task 6 stack testing, as measured by the Ontario Hydro method, detected that an average of 55% of the incoming mercury was emitted during wallboard production. These losses were distributed as about 4% across the dryer mill, 6% across the board dryer kiln, and 45% across the kettle calciner. Emissions were similar to what Task 5 results showed on a percentage basis, but about 30% lower on a mass basis. The same power plant FGD system produced the synthetic gypsum used in Task 5 (with no use of TMT-15) and in Task 6 (with TMT-15 added to the FGD system). The lower emissions on a mass basis appeared

Jessica Sanderson; Gary M. Blythe; Mandi Richardson

2006-12-01T23:59:59.000Z

412

Cryogenic homogenization of biological tissues  

Science Journals Connector (OSTI)

Cryogenic homogenization of biological tissues ... Thermal (roasting and heating in a microwave oven), mechanical (milling and cryogenic grinding), and enzymatic ... ...

Rolf Zeisler; John K. Langland; Sally H. Harrison

1983-12-01T23:59:59.000Z

413

Systems Biology | Clean Energy | ORNL  

NLE Websites -- All DOE Office Websites (Extended Search)

of interdisciplinary scientists. Additional systems biology resources Research Highlights Media Mentions Publications Newsletters Biosciences Division Recent news releases 11...

414

Perspectives Computational Biology in Brazil  

E-Print Network (OSTI)

Perspectives Computational Biology in Brazil Goran Neshich Introduction At the request of the PLoS Computational Biology Editor-in- Chief, I agreed to write about computational biology in Brazil (see author of the field itself is short); b) the current state of the field in Brazil; c) the influence of computational

Neshich, Goran

415

Brookhaven Symposium Biology 32  

NLE Websites -- All DOE Office Websites (Extended Search)

Symposium Biology 32 Symposium Biology 32 Brookhaven National Laboratory, June 1-4, 1982 NEUTRONS IN BIOLOGY, B. Schoenborn, Plenum Press N Y BNL--34681 DE84 012174 NOTICE p _ THIS R£PORT IS l £ - T . l - : T = "-T-**: TO A DEGHES THAT PRECLUDES SA u^.-.iA OKV REPRODUCTION NEUTRON SCATTERING AND THE 3 0 S RI3CS0MAL SUBUNIT OF j ^ . COLI P.B. Moore, a D.M. Enselmsn, b J.A. Langer, b V.R. Ramaicrishnan,^ _.G« Schindler, 3 B.P. Schoenborn, c I-Y. Sillers, a and S. Yabuki a a Uept. of Chemistry and ^Molecular Biophysics and Biochemistry Yale University. Nev Haven, CT 06511 c BicIogy Dapc, Srookhavse National Lab., Upton, NY 11973 INTRODUCTION Siboscmes ara nueleoprotein enzyaes which catalyze the for- mation of polypeptide chains under inRNA control, using aminoacyl tENAs as substrates-for reviawo see Nomura et al. (22) and

416

Improved practices, synthetic mud drive record 24-hr drilling  

SciTech Connect

Revised and improved drilling practices resulted in increased rate of penetration (ROP), improved hole cleaning, decreased circulating time, fewer instances of stuck pipe and reduced total drilling days. Rig equipment modifications and optimized techniques, combined with olefin-based synthetic fluid, produced significant efficiency improvements and cost reductions. Total-project strategy allows best technologies to be used, even if they are not low bid. In the Gulf of Mexico, a total-project concept helped Marathon drill back-to-back record 24-hr footages. Methods and philosophy described in this article allow drillers to choose optimum technologies, tools, materials and service performance for achieving optimum or lowest cost per foot rather than always using low bid.

Collins, G.J. [Marathon Oil Co., Houston, TX (United States); White, W.W. [Marathon Oil Co., Lafayette, LA (United States)

1995-05-01T23:59:59.000Z

417

Synthetic fuels technology overview with health and environmental impacts  

SciTech Connect

An introduction is presented to the following synthetic fuels technologies: (1) the Lurgi gasification of coal (2) the Fischer-Tropsch liquefaction of coal (3) coal-methanol conversion (4) donor solvent gas liquefaction (5) Tosco surface shale retorting ethanol production from coal and (6) the coal-methanol-gasoline conversion process. After establishing the system characteristics of these six technologies, consideration is given to their potential major health, safety, environmental and socio-economic impacts at the global, regional and local levels. It is determined that the main global consequence of synfuels development is climate modification, to which may be added the regional impact of dry and wet deposition of gaseous and particulate pollutants, and land and water quality deterioration due to soil erosion at the local level.

Bentz, E.J. Jr.; Salmon, E.J.

1981-01-01T23:59:59.000Z

418

Synthetic Biology and Bioenergy: Helping the Good Guy and Stopping the Bad (2014 DOE JGI Genomics of Energy & Environment Meeting)  

SciTech Connect

Maria Mercedes-Roca of the Zamorano Panamerican Agriculture School speaks at the 9th Annual Genomics of Energy & Environment Meeting on March 20, 2014 in Walnut Creek, Calif.

Mercedes-Roca, Maria [Zamorano Panamerican Agriculture School

2014-03-19T23:59:59.000Z

419

Synthetic biology in yeast : reconstructing the galactose network to probe the role of feedback induction in response to metabolic stimuli  

E-Print Network (OSTI)

28–37. Grilly, C. , Stricker, J. , Pang, W. L. , Bennett, M.315(5813), 801–804. Stricker, J. , Cookson, S. , Bennett, M.Danino et al. , 2010; Stricker et al. , 2008; Dunlap, 2006;

Ferry, Michael Stephen

2010-01-01T23:59:59.000Z

420

Microfluidics for Synthetic Biology : : developing technologies for study of gene networks in single cells and large populations  

E-Print Network (OSTI)

1025–1036. Grilly, C. , Stricker, J. , Pang, W. , Bennett,37(20), 4743–4750. Stricker, J. , Cookson, S. , Bennett, M.regulatory processes (Stricker et al. , 2008; Mondragon-

Razinkov, Ivan Alexandrovich

Note: This page contains sample records for the topic "organisms synthetic biology" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


421

Synthetic biology in yeast : reconstructing the galactose network to probe the role of feedback induction in response to metabolic stimuli  

E-Print Network (OSTI)

have the same resistance and equivalent P´eclet numbers.resistance somewhat. Comsol modeling allowed us to determine the port pressures which led to equivalent

Ferry, Michael Stephen

2010-01-01T23:59:59.000Z

422

Microfluidics for Synthetic Biology : : developing technologies for study of gene networks in single cells and large populations  

E-Print Network (OSTI)

have the same resistance and equivalent P´eclet numbers.resistance somewhat. Comsol modeling allowed us to determine the port pressures which led to equivalent

Razinkov, Ivan Alexandrovich

423

Metabolic Engineering and Synthetic Biology in Strain Development Every year, we consume about 27 billion barrels of fossil oil.  

E-Print Network (OSTI)

billion barrels of fossil oil. This enormous amount of oil is used for fueling our cars and airplanes

424

The Organic Rankine Cycle  

Science Journals Connector (OSTI)

Chap. 3 is dedicated to Rankine cycles with organic fluids: the so-called organic Rankine cycles (ORC), which in recent years have ... of the use of...

Costante Mario Invernizzi

2013-01-01T23:59:59.000Z

425

Organization | Department of Energy  

Energy.gov (U.S. Department of Energy (DOE)) Indexed Site

Organization Organization The Office of Economic Impact and Diversity is comprised of: The Office of the Director- contact us Office of Minority Business and Economic Development -...

426

Energy from biological processes  

SciTech Connect

This assessment responds to a request by the Senate Committee on Commerce, Science, and Transportation for an evaluation of the energy potential of various sources of plant and animal matter (biomass). This report complements an earlier OTA report on the Application of Solar Technology to Today's Energy Needs in evaluating the major solar energy resources available to the United States. The findings also will serve as part of the material to be used in an upcoming OTA assessment of synthetic fuels for transportation. This volume presents analyses of prominent biomass issues, summaries of four biomass fuel cycles, a description of biomass' place in two plausible energy futures, and discussions of policy options for promoting energy from biomass. The four fuel cycles - wood, alcohol fuels, grasses and crop residues, and animal wastes - were chosen because of their near- to mid-term energy potential and because of the public interest in them. A second volume presents technical analyses of the resource base, conversion technologies, and end uses that provide a basis for the discussion in this volume. Also included in Volume II are various unconventional approaches to bioenergy production as well as the use of biomass to produce chemicals.

Not Available

1980-07-01T23:59:59.000Z

427

Self-Organizing Mesomorphic Diketopyrrolopyrrole Derivatives for Efficient Solution-Processed Organic Solar Cells  

Science Journals Connector (OSTI)

Organic solar cells (OSCs) are drawing considerable interest for the great promise as a next-generation clean and renewable energy source. ... T.Y. is grateful for the financial support from the Murata Science Foundation, the Fujifilm Award in Synthetic Organic Chemistry, and Kyushu University Interdisciplinary Programs in Education and Projects in Research Development. ... utilizing a novel 4,9-bis(2-ethylhexyloxy)naphtho[1,2-b:5,6-b']dithiophene "zig-zag" core (zNDT) exhibits high hole mobility, upshifted frontier MO energies, and enhanced photovoltaic cell short-circuit currents, fill-factors, and power conversion efficiencies (4.7%) vs. the linear NDT isomer. ...

Woong Shin; Takuma Yasuda; Go Watanabe; Yu Seok Yang; Chihaya Adachi

2013-06-05T23:59:59.000Z

428

7.013 Introductory Biology, Spring 2005  

E-Print Network (OSTI)

The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological ...

Sive, Hazel L.

429

Estimation of Probe Cell Locations in High-density Synthetic-oligonucleotide DNA Microarrays  

E-Print Network (OSTI)

Estimation of Probe Cell Locations in High-density Synthetic-oligonucleotide DNA Microarrays Harry Institute, Durham, NC 27710 1 #12;High-density synthetic-oligonucliotide DNA microarrays (HSDMs), which area required to hybridise an RNA sample to DNA probes. On an HSDM surface, hundreds of thousands

West, Mike

430

A synthetic peptide with estrogen-like activity derived from a phage-display peptide library  

E-Print Network (OSTI)

A synthetic peptide with estrogen-like activity derived from a phage- display peptide library. ER and ER exhibit a high degree of homology at the DNA binding domain (97%) whereas at the ligand agonists or antagonists are mainly synthetic compounds prepared by modifications that retain the core

Kasher, Roni

431

Orthogonal Control of Endogenous Gene Expression in Mammalian Cells Using Synthetic Ligands  

E-Print Network (OSTI)

ARTICLE Orthogonal Control of Endogenous Gene Expression in Mammalian Cells Using Synthetic Ligands South Mathews Avenue, Urbana, Illinois 61801 ABSTRACT: Gene switches have wide utility in synthetic-finger DNA binding domain (DBD). Our gene switch is specifically and reversibly con- trolled by 4

Zhao, Huimin

432

Analysis of Combinatorial cis-Regulation in Synthetic and Genomic Promoters  

E-Print Network (OSTI)

Analysis of Combinatorial cis-Regulation in Synthetic and Genomic Promoters Jason Gertz1, Eric D. Here we present such a model based on the analysis of synthetic promoter libraries in yeast. Thermodynamic models based only on the equilibrium binding of transcription factors to DNA and to each other

Siggia, Eric

433

Constructing High Complexity Synthetic Libraries of Long ORFs Using In Vitro Selection  

E-Print Network (OSTI)

for the design and synthesis of large synthetic DNA libraries coding for protein sequences suitable for useConstructing High Complexity Synthetic Libraries of Long ORFs Using In Vitro Selection Glen Cho selection experiments. Protein libraries are often encoded by chemically synthesized DNA, in which part

Heller, Eric

434

SYNTHESIS 0.1: BETA RELEASE OF A SYNTHETIC WAVEFORMS M. D'amico1  

E-Print Network (OSTI)

SYNTHESIS 0.1: BETA RELEASE OF A SYNTHETIC WAVEFORMS REPOSITORY M. D'amico1 , F. Pacor1 , R. PugliaISmograms (SYNTHESIS 0.1). It is designed to archive and distribute synthetic waveforms computed for earthquake hazard describing each scenario-event. The structure of SYNTHESIS is adopted from the ITACA database (http

Cerveny, Vlastislav

435

Inverse-synthetic-aperture imaging of trees over a ground plane  

SciTech Connect

Recent data collections with the Sandia VHF-UHF synthetic-aperture radar have yielded surprising results; trees appear brighter in the images than expected! In an effort to understand this phenomenon, various small trees have been measured on the Sandia folded compact range with the inverse-synthetic-aperture imaging system. A compilation of these measurements is contained in this report.

Zittel, D.H.; Brock, B.C.; Littlejohn, J.H.; Patitz, W.E.

1995-11-01T23:59:59.000Z

436

Four Postmortem Case Reports with Quantitative Detection of the Synthetic Cannabinoid, 5F-PB-22  

Science Journals Connector (OSTI)

......2 (CB2). The consumption of synthetic cannabinoids...V) Collision energy (eV) 5F-PB-22...5F-PB-22. The average ion transition ratio...pronounced dead in the home of friends during...returned to his home around noon the...highs-seizures after consumption of synthetic cannabinoids......

George Behonick; Kevin G. Shanks; Dennis J. Firchau; Gagan Mathur; Charles F. Lynch; Marcus Nashelsky; David J. Jaskierny; Chady Meroueh

2014-10-01T23:59:59.000Z

437

Optimal Part and Module Selection for Synthetic Gene Circuit Design Automation  

Science Journals Connector (OSTI)

Optimal Part and Module Selection for Synthetic Gene Circuit Design Automation ... A step toward automated synthetic circuit design is the selection of a part set so that the final circuit exhibits the desired behavior. ... Our workflow is the first to automate the prodn. of biol. ...

Linh Huynh; Ilias Tagkopoulos

2014-01-28T23:59:59.000Z

438

Polishing of synthetic electroplating wastewater in microcosm upflow constructed wetlands: Metals removal mechanisms  

E-Print Network (OSTI)

Polishing of synthetic electroplating wastewater in microcosm upflow constructed wetlands: Metals in microcosm upflow constructed wetlands used for polishing of synthetic electroplating wastewater. Four types (2014) 53-42" DOI : 10.1016/j.cej.2013.12.075 #12;Keywords electroplating wastewater, metals, cyanides

Paris-Sud XI, Université de

439

Fe(II) Sorption on a Synthetic Montmorillonite. A Combined Macroscopic and Spectroscopic Study  

E-Print Network (OSTI)

Fe(II) Sorption on a Synthetic Montmorillonite. A Combined Macroscopic and Spectroscopic Study fine structure (EXAFS) and Mossbauer spectroscopy combined with macroscopic sorption experiments were employed to investigate the sorption mechanism of Fe(II) on an iron-free synthetic montmorillonite (Na

Wehrli, Bernhard

440

FSAAWG, ROME 2011 1 Synthetic Voice Forgery in the Forensic Context: a  

E-Print Network (OSTI)

FSAAWG, ROME 2011 1 Synthetic Voice Forgery in the Forensic Context: a short tutorial Guillaume Paristech, dép. TSI 37-39 rue Dareau 75014 PARIS Abstract--Technical voice forgery in the forensic area has, the forensic context is quite different since the human ear might be able to detect a synthetic voice, thus

Paris-Sud XI, Université de

Note: This page contains sample records for the topic "organisms synthetic biology" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


441

Biological constraints on habitability  

Science Journals Connector (OSTI)

......energy store for the cell. In extremely alkaline...protons across the cell membrane (outwards...of water from the cell by osmosis), but...intracellular accumulation of organic osmolytes such as...the consumption or production of gases. Thus...adequate shielding from solar ultraviolet radiation......

Lewis Dartnell

2011-02-01T23:59:59.000Z

442

The biology of methanogenic bacteria.  

Science Journals Connector (OSTI)

...redox and ionic strength of the synthetic...represented as gases; HCO3-, HC02...from a sewage sludge digestor in Urbana...123) and sewage sludge digestors (90). Sediment or sludge is added to anaerobic...and an H2-CO2 gas phase. Incubation...

J G Zeikus

1977-06-01T23:59:59.000Z

443

Synthetic jets at large Reynolds number and comparison to continuous jets  

SciTech Connect

Experimental measurements and flow visualization of synthetic jets and similar continuous jets are described. The dimensionless stroke length necessary to form a 2-D synthetic jet is between 5 and 10, with wider-nozzle jets consistently requiring a smaller value. Synthetic jets are wider, slower and have more momentum than similar continuous jets. Synthetic jets are generated using four nozzle widths that vary by a factor of four, and the driving frequency is varied over an order of magnitude. The resultant jets are in the range 13.5 < L{sub o}/h < 80.8 and 695 < Re{sub Uo} < 14700. In spite of the large range of stroke lengths, the near-field behavior of the synthetic jets scales with L{sub o}/h.

Smith, B. L. (Barton L.); Swift, G. W. (Gregory W.)

2001-01-01T23:59:59.000Z

444

Fate of Mercury in Synthetic Gypsum Used for Wallboard Production  

SciTech Connect

This report presents and discusses results from Task 5 of the study ''Fate of Mercury in Synthetic Gypsum Used for Wallboard Production,'' performed at a full-scale commercial wallboard plant. Synthetic gypsum produced by wet flue gas desulfurization (FGD) systems on coal-fired power plants is commonly used in the manufacture of wallboard. The FGD process is used to control the sulfur dioxide emissions which would result in acid rain if not controlled. This practice has long benefited the environment by recycling the FGD gypsum byproduct, which is becoming available in increasing quantities, decreasing the need to landfill this material, and increasing the sustainable design of the wallboard product. However, new concerns have arisen as recent mercury control strategies developed for power plants involve the capture of mercury in FGD systems. The objective of this study is to determine whether any mercury is released into the atmosphere when the synthetic gypsum material is used as a feedstock for wallboard production. The project is being co-funded by the U.S. DOE National Energy Technology Laboratory (Cooperative Agreement DE-FC26-04NT42080), USG Corporation, and EPRI. USG Corporation is the prime contractor, and URS Group is a subcontractor. The project scope includes five discrete tasks, each conducted at various USG wallboard plants using synthetic gypsum from different FGD systems. The five tasks were to include (1) a baseline test, then variations representing differing power plant (2) emissions control configurations, (3) treatment of fine gypsum particles, (4) coal types, and (5) FGD reagent types. However, Task 5, which was to evaluate gypsum produced from an alternate FGD reagent, could not be conducted as planned. Instead, Task 5 was conducted at conditions similar to a previous task, Task 3, although with gypsum from an alternate FGD system. In this project, process stacks in the wallboard plant have been sampled using the Ontario Hydro method. The stack locations sampled for each task include a dryer for the wet gypsum as it enters the plant and a gypsum calciner. The stack of the dryer for the wet wallboard product was also tested as part of this task, and was tested as part of Tasks 1 and 4. Also at each site, in-stream process samples were collected and analyzed for mercury concentration before and after each significant step in wallboard production. The Ontario Hydro results, process sample mercury concentration data, and process data were used to construct mercury mass balances across the wallboard plants. Task 5 was conducted at a wallboard plant processing synthetic gypsum from a power plant that fires Eastern bituminous coal. The power plant is equipped with a selective catalytic reduction (SCR) system for NOX emissions control, but the SCR was bypassed during the time period the gypsum tested was produced. The power plant has a single-loop, open spray tower, limestone reagent FGD system, with forced oxidation conducted in a reaction tank integral with the FGD absorber. The FGD system has gypsum fines blow down as part of the dewatering step. Gypsum fines blow down is believed to be an important variable that impacts the amount of mercury in the gypsum byproduct and possibly its stability during the wallboard process. The results of the Task 5 stack testing, as measured by the Ontario Hydro method, detected that an average of 51% of the incoming mercury in the FGD gypsum was emitted during wallboard production. These losses were distributed as 2% or less each across the wet gypsum dryer and product wallboard dryer, and about 50% across the gypsum calciner. Emissions were similar to what Task 3 results showed, on both a percentage and a mass basis, for gypsum produced by a power plant firing bituminous coal and also having gypsum fines blow down as part of the FGD dewatering scheme. As was seen in the Task 1 through 4 results, most of the mercury detected in the stack testing on the wet gypsum dryer and kettle calciner was in the form of elemental mercury. In the wallboard dryer kiln, a more signific

Jessica Marshall Sanderson

2006-06-01T23:59:59.000Z

445

AN INTEGRATED BIOLOGICAL CONTROL SYSTEM AT HANFORD  

SciTech Connect

In 1999 an integrated biological control system was instituted at the U.S. Department of Energy's Hanford Site. Successes and changes to the program needed to be communicated to a large and diverse mix of organizations and individuals. Efforts at communication are directed toward the following: Hanford Contractors (Liquid or Tank Waste, Solid Waste, Environmental Restoration, Science and Technology, Site Infrastructure), General Hanford Employees, and Hanford Advisory Board (Native American Tribes, Environmental Groups, Local Citizens, Washington State and Oregon State regulatory agencies). Communication was done through direct interface meetings, individual communication, where appropriate, and broadly sharing program reports. The objectives of the communication efforts was to have the program well coordinated with Hanford contractors, and to have the program understood well enough that all stakeholders would have confidence in the work performed by the program to reduce or elimated spread of radioactive contamination by biotic vectors. Communication of successes and changes to an integrated biological control system instituted in 1999 at the Department of Energy's Hanford Site have required regular interfaces with not only a diverse group of Hanford contractors (i.e., those responsible for liquid or tank waste, solid wastes, environmental restoration, science and technology, and site infrastructure), and general Hanford employees, but also with a consortium of designated stake holders organized as the Hanford Advisory Board (i.e., Native American tribes, various environmental groups, local citizens, Washington state and Oregon regulatory agencies, etc.). Direct interface meetings, individual communication where appropriate, and transparency of the biological control program were the methods and outcome of this effort.

JOHNSON AR; CAUDILL JG; GIDDINGS RF; RODRIGUEZ JM; ROOS RC; WILDE JW

2010-02-11T23:59:59.000Z

446

Transportation Organization and Functions  

Energy.gov (U.S. Department of Energy (DOE))

Office of Packaging and Transportation list of organizations and functions, with a list of acronyms.

447

Si-Directed Nitrenium Ion Cyclization: Development & Application. Novel Inhibitors of Ebola-Cell Entry.  

E-Print Network (OSTI)

??Part I: Synthetic organic chemistry is continually used for the synthesis of the desired biologically active target molecules that can be potentially used as suitable… (more)

Yermolina, Maria V.

2013-01-01T23:59:59.000Z

448

Fast 62–92 % yield preparation of amino acid dithiocarbamates in green solvent at room temperature  

Science Journals Connector (OSTI)

Dithiocarbamate and their derivatives are of importance in medicinal chemistry due to their biological activities, in agriculture as fungicides and in organic synthesis as versatile synthetic intermediates. Green

Najmedin Azizi; Mahboobe Marimi

2013-12-01T23:59:59.000Z

449

Successful Radiotherapy of Tumor in Pretargeted Mice by 188Re-Radiolabeled Phosphorodiamidate Morpholino Oligomer, a Synthetic DNA Analogue  

Science Journals Connector (OSTI)

...188Re-Radiolabeled Phosphorodiamidate Morpholino Oligomer, a Synthetic DNA Analogue Guozheng Liu 1 Requests for reprints: Guozheng...188Re-radiolabeled phosphorodiamidate morpholino oligomer, a synthetic DNA analogue. | Pretargeting has been attracting increasing...

Guozheng Liu; Shuping Dou; George Mardirossian; Jiang He; Surong Zhang; Xinrong Liu; Mary Rusckowski; Donald J. Hnatowich

2006-08-15T23:59:59.000Z

450

Nuclear magnetic resonance studies of drug-nucleic acid interactions at the synthetic DNA level in solution  

Science Journals Connector (OSTI)

Nuclear magnetic resonance studies of drug-nucleic acid interactions at the synthetic DNA level in solution ...

Dinshaw J. Patel

1979-04-01T23:59:59.000Z

451

Detection of human rotavirus by using an alkaline phosphatase-conjugated synthetic DNA probe in comparison with enzyme-linked immunoassay and polyacrylamide gel analysis.  

Science Journals Connector (OSTI)

...alkaline phosphatase-conjugated synthetic DNA probe in comparison with enzyme-linked...alkaline phosphatase-conjugated synthetic DNA probe in comparison with enzyme-linked...Alkaline Phosphatase-Conjugated Synthetic DNA Probe in Comparison with Enzyme-Linked...

D M Olive; S K Sethi

1989-01-01T23:59:59.000Z

452

An Optimized, Synthetic DNA Vaccine Encoding the Toxin A and Toxin B Receptor Binding Domains of Clostridium difficile Induces Protective Antibody Responses In Vivo  

Science Journals Connector (OSTI)

...Immunity and Vaccines An Optimized, Synthetic DNA Vaccine Encoding the Toxin A and...these advantages make newer, synthetic DNA-based immunizations a desirable...our work demonstrates that a synthetic DNA vaccine encoding the toxin RBDs...

Scott M. Baliban; Amanda Michael; Berje Shammassian; Shikata Mudakha; Amir S. Khan; Simon Cocklin; Isaac Zentner; Brian P. Latimer; Laurent Bouillaut; Meredith Hunter; Preston Marx; Niranjan Y. Sardesai; Seth L. Welles; Jeffrey M. Jacobson; David B. Weiner; Michele A. Kutzler

2014-07-14T23:59:59.000Z

453

Detection of rotavirus by hybridization with a nonradioactive synthetic DNA probe and comparison with commercial enzyme immunoassays and silver-stained polyacrylamide gels.  

Science Journals Connector (OSTI)

...hybridization with a nonradioactive synthetic DNA probe and comparison with commercial...hybridization with a nonradioactive synthetic DNA probe and comparison with commercial...Hybridization with a Nonradioactive Synthetic DNA Probe and Comparison with Commercial...

M Arens; E M Swierkosz

1989-06-01T23:59:59.000Z

454

Biological Safety | Department of Energy  

Office of Environmental Management (EM)

of best practices, lessons learned, and guidance in the area of biological safety. This content is supported by the Biosurety Executive Team. The Biosurety Executive Team is a...

455

Lynx: A High-Resolution Synthetic Aperture Radar  

SciTech Connect

Lynx is a high resolution, synthetic aperture radar (SAR) that has been designed and built by Sandia National Laboratories in collaboration with General Atomics (GA). Although Lynx may be operated on a wide variety of manned and unmanned platforms, it is primarily intended to be fielded on unmanned aerial vehicles. In particular, it may be operated on the Predator, I-GNAT, or Prowler II platforms manufactured by GA Aeronautical Systems, Inc. The Lynx production weight is less than 120 lb. and has a slant range of 30 km (in 4 mm/hr rain). It has operator selectable resolution and is capable of 0.1 m resolution in spotlight mode and 0.3 m resolution in stripmap mode. In ground moving target indicator mode, the minimum detectable velocity is 6 knots with a minimum target cross-section of 10 dBsm. In coherent change detection mode, Lynx makes registered, complex image comparisons either of 0.1 m resolution (minimum) spotlight images or of 0.3 m resolution (minimum) strip images. The Lynx user interface features a view manager that allows it to pan and zoom like a video camera. Lynx was developed under corporate finding from GA and will be manufactured by GA for both military and commercial applications. The Lynx system architecture will be presented and some of its unique features will be described. Imagery at the finest resolutions in both spotlight and strip modes have been obtained and will also be presented.

Doerry, A.W.; Hensley, W.H.; Pace, F.; Stence, J.; Tsunoda, S.I.; Walker, B.C.; Woodring, M.

1999-03-08T23:59:59.000Z

456

Cyclic testing of continuously wetted synthetic fiber ropes  

SciTech Connect

A laboratory study of the cyclic loading endurance properties of continuously wetted synthetic, or manmade, fibre ropes has been conducted on ropes of various materials and forms of construction. The materials investigated were polyamides, polyester and polypropylene. Forms of construction studied were braid-on-braid, eight strand (square) and parallel lay. Rope sizes researched were 100 kN (10 tonf) nominal breaking force and up to 1.0 MN (100 tonf) nominal breaking force. All specimens were single leg. The test results indicate the superior bollard abrasion resistance and interstrand friction wear resistance of polyester and polypropylene over the polyamides. Trends, where observed, are also reported upon for the cyclic endurance performance of the forms of construction investigated. The improvements (or otherwise) in endurance effected by sheathing, coating and thimble protection of the eyes are also discussed. The results and performance trends observed on this test programme will be of interest to designers and users of mooring or tethering systems which operate continuously wet.

Crawford, H.; McTernan, L.M.

1983-05-01T23:59:59.000Z

457

Observation of Dirac Monopoles in a Synthetic Magnetic Field  

E-Print Network (OSTI)

Magnetic monopoles --- particles that behave as isolated north or south magnetic poles --- have been the subject of speculation since the first detailed observations of magnetism several hundred years ago. Numerous theoretical investigations and hitherto unsuccessful experimental searches have followed Dirac's 1931 development of a theory of monopoles consistent with both quantum mechanics and the gauge invariance of the electromagnetic field. The existence of even a single Dirac magnetic monopole would have far-reaching physical consequences, most famously explaining the quantization of electric charge. Although analogues of magnetic monopoles have been found in exotic spin-ices and other systems, there has been no direct experimental observation of Dirac monopoles within a medium described by a quantum field, such as superfluid helium-3. Here we demonstrate the controlled creation of Dirac monopoles in the synthetic magnetic field produced by a spinor Bose-Einstein condensate. Monopoles are identified, in both experiments and matching numerical simulations, at the termini of vortex lines within the condensate. By directly imaging such a vortex line, the presence of a monopole may be discerned from the experimental data alone. These real-space images provide conclusive and long-awaited experimental evidence of the existence of Dirac monopoles. Our result provides an unprecedented opportunity to observe and manipulate these quantum-mechanical entities in a controlled environment.

M. W. Ray; E. Ruokokoski; S. Kandel; M. Möttönen; D. S. Hall

2014-08-13T23:59:59.000Z

458

Production of synthetic gasoline and diesel fuel from nonpetroleum resources  

SciTech Connect

In late 1985, the New Zealand Gas-to-Gasoline Complex was successfully streamed producing high octane gasoline from natural gas. The heart of this complex is the Mobil fixed-bed Methanol-to-Gasoline (MTG) section which represents one of several newly developed technologies for production of synthetic gasoline and diesel fuels. All of these technologies are based on production of methanol by conventional technology, followed by conversion of the methanol to transportation fuel. The fixed-bed (MTG) process has been developed and commercialized. The fluid-bed version of the MTG process, which is now also available for commercial license, has a higher thermal efficiency and possesses substantial yield and octane number advantages over the fixed-bed. Successful scale-up was completed in 1984 in a 100 BPD semi-works plant in Wesseling, Federal Republic of Germany. The project was funded jointly by the U.S. and German governments and by the industrial participants: Mobil, Union Rheinsche Braunkohlen Kraftstoff, AG; and Uhde, GmbH. This fluid-bed MTG project was extended recently to demonstrate a related fluid-bed process for selective conversion of methanol to olefins (MTO). The MTO process can be combined with Mobil's commercially available olefins conversion process (Mobil-Olefins-to-Gasoline-and-Distillate, MOGD) for coproduction of high quality gasoline and distillate via methanol. This MTO process was also successfully demonstrated at the Wesseling semiworks with this project being completed in late 1985.

Tabak, S.A.; Avidan, A.A.; Krambeck, F.J.

1986-04-01T23:59:59.000Z

459

The emerging technology of synthetic aperture focusing for ultrasonic testing  

SciTech Connect

The capabilities of synthetic aperture focusing techniques for ultrasonic testing (SAFT-UT) as a nondestructure testing technique are presented. SAFT-UT is a digital ultrasonic imaging method, which can be adapted to many different materials, specimen geometries, and wave propagation modes. The process allows each point within the inspected volume to be focused upon by mathematically simulating the action of a lens, specifically formed for imaging that point in the volume. All points are therefore imaged at the maximum available resolution. The PNL effort in SAFT-UT is a continuation of a program started earlier by the NRC at the University of Michigan. The objectives of the present program are: (1) to engineer and evaluate a real-time flaw detection and imaging system based on SAFT-UT for inservice inspection of all required LWR components, (2) to establish calibration and field test procedures, (3) to demonstrate and validate the system through field reactor inspections, and (4) to gain ASME Code acceptance of the real-time SAFT-UT technique. The following aspects of SAFT-UT are presented in this paper: (1) brief overview of SAFT imaging theory, (2) results demonstrating achievable lateral resolution, and (3) presentation of shear wave SAFT-UT images.

Busse, L.J.; Collins, H.D.; Doctor, S.R.

1984-06-01T23:59:59.000Z

460

Salient Biological Features, Systematics,  

NLE Websites -- All DOE Office Websites (Extended Search)

Salient Salient Biological Features, Systematics, and Genetic Variation of Populus Gancho T. Slavov and Peter Zhelev Abstract The genus Populus includes morphologically diverse species of decid- uous, relatively short-lived, and fast-growing trees. Most species have wide ranges of distribution but tend to occur primarily in riparian or mountainous habitats. Trees from this genus are typically dioecious, flower before leaf emer- gence, and produce large amounts of wind-dispersed pollen or seeds. Seedlings are drought- and shade-intolerant, and their establishment depends on distur- bance and high soil moisture. Asexual reproduction is common and occurs via root sprouting and/or rooting of shoots. Fossil records suggest that the genus appeared in the late Paleocene or early Eocene (i.e., 50-60 million years BP). According to one commonly used classification, the genus is comprised

Note: This page contains sample records for the topic "organisms synthetic biology" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


461

Natural and synthetic DNA elements with the CArG motif differ in expression and protein-binding properties.  

Science Journals Connector (OSTI)

...research-article Research Article Natural and synthetic DNA elements with the CArG motif differ...cognate promoters. Natural and synthetic DNA elements with the CArG motif differ...Vol. 11, No. 12 Natural and Synthetic DNA Elements with the CArG Motif Differ...

I M Santoro; K Walsh

1991-12-01T23:59:59.000Z

462

Ultrafast Spectroscopic Study on Caffeine Mediated Dissociation of Mutagenic Ethidium from Synthetic DNA and Various Cell Nuclei  

Science Journals Connector (OSTI)

Ultrafast Spectroscopic Study on Caffeine Mediated Dissociation of Mutagenic Ethidium from Synthetic DNA and Various Cell Nuclei ... (10) The purified (reverse-phase cartridge) synthetic DNA oligonucleotides of 12 bases (dodecamer) with sequence CGCGAATTCGCG were obtained from TriLink. ... In Figure 1a,b steady-state and time-resolved studies on the Et intercalated to the synthetic DNA are presented. ...

Soma Banerjee; Debajit Bhowmik; Pramod Kumar Verma; Rajib Kumar Mitra; Anirban Sidhhanta; Gautam Basu; Samir Kumar Pal

2011-10-27T23:59:59.000Z

463

Face-to-Face and Edge-to-Face ??? Interactions in a Synthetic DNA Hairpin with a Stilbenediether Linker  

Science Journals Connector (OSTI)

Face-to-Face and Edge-to-Face ??? Interactions in a Synthetic DNA Hairpin with a Stilbenediether Linker ... This property allowed investigation of hole injection and migration processes in the synthetic DNA hairpins. ... Structure and Photoinduced Electron Transfer in Exceptionally Stable Synthetic DNA Hairpins with Stilbenediether Linkers ...

Martin Egli; Valentina Tereshko; Garib N. Mushudov; Ruslan Sanishvili; Xiaoyang Liu; Frederick D. Lewis

2003-08-16T23:59:59.000Z

464

1008 ieee transactions on ultrasonics, ferroelectrics, and frequency control, vol. 53, no. 5, may 2006 An Iterative Synthetic Aperture Imaging  

E-Print Network (OSTI)

as synthetic aperture focusing technique (SAFT) [1] has been inspired by synthetic aperture sonar (SAS) [2] and synthetic aper- ture radar (SAR) [3]. SAFT has been applied both in med- ical and nondestructive material that this technique is superior to many other common SAI algo- rithms, such as conventional SAFT and phased-array tech

465

Network biology methods integrating biological data for translational science  

E-Print Network (OSTI)

types into a biologically meaningful frame- work suitable for joint analysis. Biological regulation, driving cooperation or competition be- tween different genes and proteins, are hallmarks of population is Assistant Professor of Electrical Engineering and Computer Science and Proteomics and Bioinformatics at Case

Koyuturk, Mehmet

466

CORNELL UNIVERSITY Department of Biological Statistics and Computational Biology  

E-Print Network (OSTI)

or BTRY 6020: Statistical Methods II BTRY 3080: Probability Models and Inference MATH 1110, Calculus ICORNELL UNIVERSITY Department of Biological Statistics and Computational Biology Requirements for a Minor in Biometry and Statistics 7/23/14 DESCRIPTION OF THE MINOR The Minor in Biometry and Statistics

Keinan, Alon

467

Mixed crystal organic scintillators  

DOE Patents (OSTI)

A mixed organic crystal according to one embodiment includes a single mixed crystal having two compounds with different bandgap energies, the organic crystal having a physical property of exhibiting a signal response signature for neutrons from a radioactive source, wherein the signal response signature does not include a significantly-delayed luminescence characteristic of neutrons interacting with the organic crystal relative to a luminescence characteristic of gamma rays interacting with the organic crystal. According to one embodiment, an organic crystal includes bibenzyl and stilbene or a stilbene derivative, the organic crystal having a physical property of exhibiting a signal response signature for neutrons from a radioactive source.

Zaitseva, Natalia P; Carman, M Leslie; Glenn, Andrew M; Hamel, Sebastien; Hatarik, Robert; Payne, Stephen A; Stoeffl, Wolfgang

2014-09-16T23:59:59.000Z

468

Driving Force Dependence of Electron Transfer Dynamics in Synthetic DNA Hairpins  

Science Journals Connector (OSTI)

Driving Force Dependence of Electron Transfer Dynamics in Synthetic DNA Hairpins ... The driving force dependence of photoinduced electron-transfer dynamics in duplex DNA has been investigated for 16 synthetic DNA hairpins in which an acceptor chromophore serves as a linker connecting two complementary oligonucleotide arms containing a single donor nucleobase located either adjacent to the linker or separated from the linker by two unreactive base pairs. ... for a family of synthetic DNA hairpins in which a stilbene dicarboxamide forms a bridge connecting two oligonucleotide arms. ...

Frederick D. Lewis; Rajdeep S. Kalgutkar; Yansheng Wu; Xiaoyang Liu; Jianqin Liu; Ryan T. Hayes; Scott E. Miller; Michael R. Wasielewski

2000-11-23T23:59:59.000Z

469

Synthetic Nano-Low Density Lipoprotein as Targeted Drug DeliveryVehicle for Glioblastoma Multiforme  

SciTech Connect

This paper discribes a synthetic low density lipoprotein(LDL) made by complexing a 29 amino acid that consists of a lipid bindingdomain and the LDL receptor binding domain with a lipid microemulsion.The nano-LDL particles were intermdiate in size between LDL and HDL andbound to LDL receptors on GBM brain tumor cells. Synthetic nano-LDLuptake by GBM cells was LDL receptor specific and dependent on cellreceptor number. It is suggested that these synthetic particles can serveas a delivery vehicle for hydophobic anti-tumor drugs by targeting theLDL receptor.

Nikanjam, Mina; Blakely, Eleanor A.; Bjornstad, Kathleen A.; Shu,Xiao; Budinger, Thomas F.; Forte, Trudy M.

2006-06-14T23:59:59.000Z

470

Supporting Organizations | Neutron Science | ORNL  

NLE Websites -- All DOE Office Websites (Extended Search)

support the researchers and maintain the instruments used across all of our neutron science research: Biology and Soft Matter Division The Biology and Soft Matter...

471

Approaches for biological and biomimetic energy conversion  

Science Journals Connector (OSTI)

...fully synthetic and/or hybrid devices is still in its...costs are related to infrastructure, such as supporting...power inverters, and grid connections. For example...6.86/W), with infrastructure comprising 35–40...use synthetic and/or hybrid approaches to mimic...

David A. LaVan; Jennifer N. Cha

2006-01-01T23:59:59.000Z

472

ANAEROBIC BIOLOGICAL TREATMENT OF PRODUCED WATER  

SciTech Connect

During the production of oil and gas, large amounts of water are brought to the surface and must be disposed of in an environmentally sensitive manner. This is an especially difficult problem in offshore production facilities where space is a major constraint. The chief regulatory criterion for produced water is oil and grease. Most facilities have little trouble meeting this criterion using conventional oil-water separation technologies. However, some operations have significant amounts of naphthenic acids in the water that behave as oil and grease but are not well removed by conventional technologies. Aerobic biological treatment of naphthenic acids in simulated-produced water has been demonstrated by others; however, the system was easily overloaded by the large amounts of low-molecular-weight organic acids often found in produced waters. The objective of this research was to determine the ability of an anaerobic biological system to treat these organic acids in a simulated produced water and to examine the potential for biodegradation of the naphthenic acids in the anaerobic environment. A small fixed-film anaerobic biological reactor was constructed and adapted to treat a simulated produced water. The bioreactor was tubular, with a low-density porous glass packing material. The inocula to the reactor was sediment from a produced-water holding pond from a municipal anaerobic digester and two salt-loving methanogenic bacteria. During start-up, the feed to the reactor contained glucose as well as typical produced-water components. When glucose was used, rapid gas production was observed. However, when glucose was eliminated and the major organic component was acetate, little gas was generated. Methane production from acetate may have been inhibited by the high salt concentrations, by sulfide, or because of the lack, despite seeding, of microbes capable of converting acetate to methane. Toluene, a minor component of the produced water (0.1 g/L) was removed in the reactor. Batch tests were conducted to examine naphthenic acid biodegradability under several conditions. The conditions used were seed from the anaerobic reactor, wetland sediments under aerobic and anaerobic conditions, and a sterile control. The naphthenic acid was from a commercial source isolated from Gulf Coast petroleum as was dosed at 2 mg/mL. The incubations were for 30 days at 30 C. The results showed that the naphthenic acids were not biodegraded under anaerobic conditions, but were degraded under aerobic conditions. Despite poor performance of the anaerobic reactor, it remains likely that anaerobic treatment of acetate, toluene, and, potentially, other produced-water components is feasible.

John R. Gallagher

2001-07-31T23:59:59.000Z

473

Organization of the circadian clock and control of rhythmicity in fungi  

E-Print Network (OSTI)

Circadian rhythms in biological processes occur in a wide range of organisms and are generated by endogenous oscillators. In Neurospora crassa, the FRQ-oscillator (comprised of FRQ, WC-1 and WC-2) is essential for rhythms in asexual sporulation...

Greene, Andrew Vanderford

2006-10-30T23:59:59.000Z

474

Multispectral detection of organic residues on poultry processing plant equipment based on hyperspectral reflectance imaging technique  

Science Journals Connector (OSTI)

Diluted organic residues, such as feces, ingesta and other biological substances on poultry processing plant equipment surfaces, not easily discernible by human eye, are potential contamination sources for poultry carcasses. Development of sensitive ... Keywords: Fecal contamination, Hyperspectral, Multispectral, Reflectance image

Byoung-Kwan Cho; Yud-Ren Chen; Moon S. Kim

2007-07-01T23:59:59.000Z

475

Semitransparent organic solar cells  

Science Journals Connector (OSTI)

The organic solar cell technology has attracted great interests due to ... low cost solution process capability. Bulk heterojunction organic solar cells offer a potentially much cheaper alternative way to harness...

Furong Zhu

2014-03-01T23:59:59.000Z

476

Quantitative biology of single neurons  

Science Journals Connector (OSTI)

...1930-1931. 25 Pawley, J. B. 2006 Handbook of biological confocal microscopy. New...NY: Springer. 26 Grupen, C. 2011 Handbook of particle detection and imaging. New...biological systems are single cells. Fundamental insights gained from single-cell analysis...

2012-01-01T23:59:59.000Z

477

Biological Diversity, Soils, and Economics  

Science Journals Connector (OSTI)

...Terrestrial biological diversity is supported by solar energy captured by plants growing in soil...Terrestrial biological diversity is supported by solar energy captured by plants growing in soil...Bhutan e De*Panara X 15 e* Norway i Tanzania_ * Costa Rica * *SnLanka &F.R.Germany...

Michael Huston

1993-12-10T23:59:59.000Z

478

Guidelines Graduate Studies In Biology  

E-Print Network (OSTI)

Department of Biology Virginia Commonwealth University 1000 W. Cary St. Richmond, VA 23284-2012 Telephone: Application for Independent Study (BIOL 692) 19 #12;1 Introduction This document is intended to serve. The Master of Science program for the graduate student in biology is administered by the College

Bukaveckas, Paul A.

479

Organic photosensitive devices  

DOE Patents (OSTI)

The present invention generally relates to organic photosensitive optoelectronic devices. More specifically, it is directed to organic photosensitive optoelectronic devices having a photoactive organic region containing encapsulated nanoparticles that exhibit plasmon resonances. An enhancement of the incident optical field is achieved via surface plasmon polariton resonances. This enhancement increases the absorption of incident light, leading to a more efficient device.

Rand, Barry P; Forrest, Stephen R

2013-11-26T23:59:59.000Z

480

Modeling disease-related proteins in Saccharomyces cerevisiae : insights into alpha-synuclein and TorsinA biology  

E-Print Network (OSTI)

The yeast Saccharomyces cerevisiae has long been used to model complex cellular processes. As a eukaryote, much of its fundamental biology is conserved with higher organisms. As a single-celled, genetically tractable ...

Valastyan, Julie S. (Julie Suzanne)

2013-01-01T23:59:59.000Z

Note: This page contains sample records for the topic "organisms synthetic biology" from the National Library of EnergyBeta (NLEBeta).
While these samples are representative of the content of NLEBeta,
they are not comprehensive nor are they the most current set.
We encourage you to perform a real-time search of NLEBeta
to obtain the most current and comprehensive results.


481

BS in BIOLOGY (282022) MAP Sheet Department of Biology  

E-Print Network (OSTI)

Chem 106 General College Chemistry Chem 107 General College Chemistry Lab Chem 351 Organic Chemistry Chem 352 Organic Chemistry Chem 353 Organic Chemistry Lab Complete one of the following options: a (65­69 total hours*) UNIVERSITY CORE REQUIREMENTS Requirements Doctrinal Foundation Book of Mormon New

Olsen Jr., Dan R.

482

Faculty of Science Biology and Biotechnology  

E-Print Network (OSTI)

Faculty of Science Biology and Biotechnology Biology is one of the Life Sciences, which describe investigation and theoretical explanation. www.uwindsor.ca/biology Biotechnology is the synthesis of important biological molecules using living systems. Rigorous, Enriching Programs The Biology and Biotechnology program

483

Effect of a synthetic leu-enkephalin analog on the intensity of DNA synthesis in insects  

Science Journals Connector (OSTI)

The hexapeptide dalargin (a synthetic analog of leu-enkephalin) injected in the...Galleria mellonella) and of mealworm (Tenebrio molitor...) causes a dose-dependent increase in the DNA content and an increase in ...

T. I. Lapteva; N. O. Min’kova…

1997-04-01T23:59:59.000Z

484

A novel synthetic DNA minor groove binder, MS-247: antitumor activity and cytotoxic mechanism  

Science Journals Connector (OSTI)

Purpose: MS-247 is a novel synthetic compound possessing a DNA-binding moiety and a DNA-alkylating residue, chlorambucil. In this study, ... murine tumor cell lines and its effects on DNA molecul...

Y. Matsuba; H. Edatsugi; I. Mita; A. Matsunaga…

2000-06-01T23:59:59.000Z

485

DNA synthetic phase duration of mouse ileal epithelium in acute renal failure  

Science Journals Connector (OSTI)

The effect of progressive acute renal failure on the DNA synthetic phase duration of ileal epithelium was assessed...3-thymidine approximately 18 hours after urinary outflow obstruction in mice. Controls were sub...

Francis T. McDermott; Melinda K. Dalton

486

Nuclear DNA content in allopolyploid species and synthetic hybrids in the grass genus Paspalum  

Science Journals Connector (OSTI)

DNA content was estimated by flow cytometry in...Paspalum and five synthetic hybrids. Results were compared to known genome constitutions and phylogenetic relationships. DNA 2C-values ranged from 1.24 pg...P. jue...

M. Vaio; C. Mazzella; V. Porro; P. Speranza…

2007-05-01T23:59:59.000Z

487

Synthetic Lethality”: Molecular Co-targeting to Restore the DNA Repair Mechanisms in Prostate Cancer Cells  

Science Journals Connector (OSTI)

To this end, PARP inhibitors are the well-known class of drugs that have recently been proposed to reach synthetic lethality in DNA repair-defective, radio-resistant prostate tumors.

Gennaro Ilardi; Stefania Staibano

2013-01-01T23:59:59.000Z

488

Depression of Protein Synthetic Capacity Due to Cloned-Gene Expression in E. coli  

E-Print Network (OSTI)

Depression of Protein Synthetic Capacity Due to Cloned-Gene Expression in E. coli Thomas K. Wood using pulse-labelling and RNA-DNA hybridiza- tions. Specifically, the steady-state level, synthesis rate

Wood, Thomas K.

489

Stabilization of DNA Triple Helices Using Conjugates of Oligonucleotides and Synthetic Ligands  

Science Journals Connector (OSTI)

The possibility is discussed of stabilizing a DNA triple helix by covalent conjugation to the ... triplex-specific intercalators. As a target, a synthetic 29-mer duplex containing a natural polypurine...

A. N. Sinyakov; V. A. Ryabinin; G. N. Grimm; A. S. Boutorine

2001-03-01T23:59:59.000Z

490

Consequences of Substituting 2NH2A for a in Synthetic DNA’S  

Science Journals Connector (OSTI)

Chemical and spectroscopic consequences of replacing A with 2NH2A have been examined in a variety of synthetic DNA’s. This substitution, which permits formation...m elevation, however, is much smaller in the deox...

Frank B. Howard; H. Todd Miles

1983-01-01T23:59:59.000Z

491

Thermal stability of synthetic aurichalcite implications for making mixed metal oxides for use as catalysts  

Science Journals Connector (OSTI)

TG combined with MS has been used to study the thermal decomposition of a synthetic aurichalcite with varying copper-zinc ratios from 0....3 and CuCO3.... A higher temperature decomposition at around 805°C, based...

R. L. Frost; A. J. Locke; M. C. Hales…

2008-10-01T23:59:59.000Z

492

Structural Analysis of Human and Bovine Bone for Development of Synthetic Materials  

E-Print Network (OSTI)

bones, as well as mimicking nature by developing a synthetic material to repair bones. Experimentally, bovine bone, tumor-free human bone, and cancerous human bone were studied via the small scale mechanical loading test. Failure analysis was conducted...

Jang, Eunhwa

2012-10-19T23:59:59.000Z

493

BTI Undergraduate Fellows Biotechnology, biofuels, synthetic ecology summer research fellowships for undergraduates at  

E-Print Network (OSTI)

BTI Undergraduate Fellows Biotechnology, biofuels, synthetic ecology summer research fellowships for undergraduates at the University of Minnesota's Biotechnology Institute. Summer research fellowships available of a faculty mentor in the Biotechnology Institute. The fellowship includes special activities for professional

Weiblen, George D

494

BTI undergraduate fellows Biotechnology, biofuels, synthetic ecology summer research fellowships for  

E-Print Network (OSTI)

BTI undergraduate fellows Biotechnology, biofuels, synthetic ecology summer research fellowships for undergraduates at the University of Minnesota's Biotechnology Institute. Summer research fellowships available of a faculty mentor in the Biotechnology Institute. The fellowship includes special activities for professional

Amin, S. Massoud

495

A Path to the Formulation of New Generations of Synthetic Jet Fuel Derived from Natural Gas  

E-Print Network (OSTI)

with industry and academia to study synthetic jet fuels derived from natural gas. These studies are being implemented at its Fuel Characterization Lab where the most advanced testing equipment is used and strict Quality Management and safety systems are followed...

Al-Nuaimi, Ibrahim Awni Omar Hassan

2013-05-20T23:59:59.000Z

496

Experimental plant for production of synthetic triplex-polymerized ethylene-propylene rubber  

Science Journals Connector (OSTI)

An experimental plant with an output of 500 kg/day, which is intended for the formulation of process production regimes, and the running times of experimental ... various grades of synthetic triple-polymerized et...

V. I. Peretyatko; V. P. Pogrebtsov; V. A. Shepelin

2010-05-01T23:59:59.000Z

497

Volumetric analysis of fish swimming hydrodynamics using synthetic aperture particle image velocimetry  

E-Print Network (OSTI)

Abstract This thesis details the implementation of a three-dimensional PIV system to study the hydrodynamics of freely swimming Giant Danio (Danio aequipinnatus). Volumetric particle fields are reconstructed using synthetic ...

Mendelson, Leah Rose

2013-01-01T23:59:59.000Z

498

Ribozyme-based "insulator parts" buffer synthetic circuits from genetic context  

E-Print Network (OSTI)

Synthetic genetic programs are built from circuits that integrate sensors and implement temporal control of gene expression1–4. Transcriptional circuits are layered by using promoters to carry the signal between circuits. ...

Lou, Chunbo

499

A fast, robust and tunable synthetic gene oscillator Jesse Stricker1  

E-Print Network (OSTI)

LETTERS A fast, robust and tunable synthetic gene oscillator Jesse Stricker1 *, Scott Cookson1 *, Matthew R. Bennett1,2 *, William H. Mather1 , Lev S. Tsimring2 & Jeff Hasty1,2 One defining goal

Hasty, Jeff

500

Development of a high-resolution gamma-ray imaging system with synthetic collimation.  

E-Print Network (OSTI)

??This work outlines the development of a multi-pinhole single-photon emission computed tomography (SPECT) system designed to produce a synthetic-collimator image of a small field of… (more)

Havelin, Ronan

2013-01-01T23:59:59.000Z