National Library of Energy BETA

Sample records for oral reference dose

  1. Dose homogeneity specification for reference dosimetry of nonstandard fields

    SciTech Connect (OSTI)

    Chung, Eunah; Soisson, Emilie; Seuntjens, Jan [Medical Physics Unit, McGill University, Montreal General Hospital (L5-113), 1650 Cedar Avenue, Montreal, Quebec H3G 1A4 (Canada); Medical Physics Unit, McGill University and Department of Medical Physics, McGill University Health Centre, Montreal General Hospital (L5-113), 1650 Cedar Avenue, Montreal, Quebec H3G 1A4 (Canada); Medical Physics Unit, McGill University, Montreal General Hospital (L5-113), 1650 Cedar Avenue, Montreal, Quebec H3G 1A4 (Canada)

    2012-01-15

    Purpose: To investigate the sensitivity of the plan-class specific correction factor to dose distributions in composite nonstandard field dosimetry. Methods: A cylindrical water-filled PMMA phantom was constructed at the center of which reference absorbed dose could be measured. Ten different TomoTherapy-based IMRT fields were created on the CT images of the phantom. The dose distribution for each IMRT field was estimated at the position of a radiation detector or ionization chamber. The dose in each IMRT field normalized to that in a reference 10 x 10 cm{sup 2} field was measured using a PTW micro liquid ion chamber. Based on the new dosimetry formalism, a plan-class specific correction factor k{sub Q{sub p{sub c{sub s{sub r,Q}{sup f{sub p}{sub c}{sub s}{sub r},f{sub r}{sub e}{sub f}}}}}} for each field was measured for two Farmer-type chambers, Exradin A12 and NE2571, as well as for a smaller Exradin A1SL chamber. The dependence of the measured correction factor on parameters characterizing dose distribution was analyzed. Results: Uncertainty on the plan-class specific correction factor measurement was in the range of 0.3%-0.5% and 0.3%-0.8% for the Farmer-type chambers and the Exradin A1SL, respectively. When the heterogeneity of the central region of the target volume was less than 5%, the correction factor did not differ from unity by more than 0.7% for the three air-filled ionization chambers. For more heterogeneous dose deliveries, the correction factor differed from unity by up to 2.4% for the Farmer-type chambers. For the Exradin A1SL, the correction factor was closer to unity due to the reduced effect of dose gradients, while it was highly variable in different IMRT fields because of a more significant impact of positioning uncertainties on the response of this chamber. Conclusions: The authors have shown that a plan-class specific correction factor can be specified as a function of plan evaluation parameters especially for Farmer-type chambers. This work provides a recipe based on quantifying dose distribution to accurately select air-filled ionization chamber correction factors for nonstandard fields.

  2. ORAL REFERENCE: ICF100572OR FIDUCIAL MARKS AS MEASURES OF THIN FILM

    E-Print Network [OSTI]

    Volinsky, Alex A.

    ORAL REFERENCE: ICF100572OR FIDUCIAL MARKS AS MEASURES OF THIN FILM CRACK ARREST TOUGHNESS Alex A presented in the paper. KEYWORDS Fiducial marks, adhesion, fracture, delamination, crack arrest, crack tip). This technique was shown to work with ductile metallic films (Al, Cu, Au, Cr) [2, 4-9, 15], ceramic (Ta2N) [10

  3. Pharmacokinetics of cisapride in normal healthy cats and recommended oral dosing regimen 

    E-Print Network [OSTI]

    LeGrange, Suzanne Nauman

    1996-01-01

    treated with either 1 mg/kg (IV) or 2 mg/kg (PO) after a 24 hour fast. Blood samples were collected intermittently for 36 hours following administration. Cats were studied in pairs using a random crossover design in which a cat receiving an oral dose...

  4. Prospective Evaluation to Establish a Dose Response for Clinical Oral Mucositis in Patients Undergoing Head-and-Neck Conformal Radiotherapy

    SciTech Connect (OSTI)

    Narayan, Samir Lehmann, Joerg; Coleman, Matthew A.; Vaughan, Andrew; Yang, Claus Chunli; Enepekides, Danny; Farwell, Gregory; Purdy, James A.; Laredo, Grace; Nolan, Kerry A.S.; Pearson, Francesca S.; Vijayakumar, Srinivasan

    2008-11-01

    Purpose: We conducted a clinical study to correlate oral cavity dose with clinical mucositis, perform in vivo dosimetry, and determine the feasibility of obtaining buccal mucosal cell samples in patients undergoing head-and-neck radiation therapy. The main objective is to establish a quantitative dose response for clinical oral mucositis. Methods and Materials: Twelve patients undergoing radiation therapy for head-and-neck cancer were prospectively studied. Four points were chosen in separate quadrants of the oral cavity. Calculated dose distributions were generated by using AcQPlan and Eclipse treatment planning systems. MOSFET dosimeters were used to measure dose at each sampled point. Each patient underwent buccal sampling for future RNA analysis before and after the first radiation treatment at the four selected points. Clinical and functional mucositis were assessed weekly according to National Cancer Institute Common Toxicity Criteria, Version 3. Results: Maximum and average doses for sampled sites ranged from 7.4-62.3 and 3.0-54.3 Gy, respectively. A cumulative point dose of 39.1 Gy resulted in mucositis for 3 weeks or longer. Mild severity (Grade {<=} 1) and short duration ({<=}1 week) of mucositis were found at cumulative point doses less than 32 Gy. Polymerase chain reaction consistently was able to detect basal levels of two known radiation responsive genes. Conclusions: In our sample, cumulative doses to the oral cavity of less than 32 Gy were associated with minimal acute mucositis. A dose greater than 39 Gy was associated with longer duration of mucositis. Our technique for sampling buccal mucosa yielded sufficient cells for RNA analysis using polymerase chain reaction.

  5. Reference computations of public dose and cancer risk from airborne releases of plutonium. Nuclear safety technical report

    SciTech Connect (OSTI)

    Peterson, V.L.

    1993-12-23

    This report presents results of computations of doses and the associated health risks of postulated accidental atmospheric releases from the Rocky Flats Plant (RFP) of one gram of weapons-grade plutonium in a form that is respirable. These computations are intended to be reference computations that can be used to evaluate a variety of accident scenarios by scaling the dose and health risk results presented here according to the amount of plutonium postulated to be released, instead of repeating the computations for each scenario. The MACCS2 code has been used as the basis of these computations. The basis and capabilities of MACCS2 are summarized, the parameters used in the evaluations are discussed, and results are presented for the doses and health risks to the public, both the Maximum Offsite Individual (a maximally exposed individual at or beyond the plant boundaries) and the population within 50 miles of RFP. A number of different weather scenarios are evaluated, including constant weather conditions and observed weather for 1990, 1991, and 1992. The isotopic mix of weapons-grade plutonium will change as it ages, the {sup 241}Pu decaying into {sup 241}Am. The {sup 241}Am reaches a peak concentration after about 72 years. The doses to the bone surface, liver, and whole body will increase slightly but the dose to the lungs will decrease slightly. The overall cancer risk will show almost no change over this period. This change in cancer risk is much smaller than the year-to-year variations in cancer risk due to weather. Finally, x/Q values are also presented for other applications, such as for hazardous chemical releases. These include the x/Q values for the MOI, for a collocated worker at 100 meters downwind of an accident site, and the x/Q value integrated over the population out to 50 miles.

  6. Reference computations of public dose and cancer risk from airborne releases of uranium and Class W plutonium

    SciTech Connect (OSTI)

    Peterson, V.L.

    1995-06-06

    This report presents ``reference`` computations that can be used by safety analysts in the evaluations of the consequences of postulated atmospheric releases of radionuclides from the Rocky Flats Environmental Technology Site. These computations deal specifically with doses and health risks to the public. The radionuclides considered are Class W Plutonium, all classes of Enriched Uranium, and all classes of Depleted Uranium. (The other class of plutonium, Y, was treated in an earlier report.) In each case, one gram of the respirable material is assumed to be released at ground leveL both with and without fire. The resulting doses and health risks can be scaled to whatever amount of release is appropriate for a postulated accident being investigated. The report begins with a summary of the organ-specific stochastic risk factors appropriate for alpha radiation, which poses the main health risk of plutonium and uranium. This is followed by a summary of the atmospheric dispersion factors for unfavorable and typical weather conditions for the calculation of consequences to both the Maximum Offsite Individual and the general population within 80 km (50 miles) of the site.

  7. Reference air kerma and kerma-area product as estimators of peak skin dose for fluoroscopically guided interventions

    SciTech Connect (OSTI)

    Kwon, Deukwoo; Little, Mark P.; Miller, Donald L. [Radiation Epidemiology Branch, National Cancer Institute, Division of Cancer Epidemiology and Genetics, Bethesda, Maryland 20852-7238 (United States); Radiation Epidemiology Branch, National Cancer Institute, Division of Cancer Epidemiology and Genetics, Bethesda, Maryland 20852-7238 and Department of Radiology and Radiological Sciences, F. Edward Hebert School of Medicine, Uniformed Services University, Bethesda, Maryland 20814 (United States)

    2011-07-15

    Purpose: To determine more accurate regression formulas for estimating peak skin dose (PSD) from reference air kerma (RAK) or kerma-area product (KAP). Methods: After grouping of the data from 21 procedures into 13 clinically similar groups, assessments were made of optimal clustering using the Bayesian information criterion to obtain the optimal linear regressions of (log-transformed) PSD vs RAK, PSD vs KAP, and PSD vs RAK and KAP. Results: Three clusters of clinical groups were optimal in regression of PSD vs RAK, seven clusters of clinical groups were optimal in regression of PSD vs KAP, and six clusters of clinical groups were optimal in regression of PSD vs RAK and KAP. Prediction of PSD using both RAK and KAP is significantly better than prediction of PSD with either RAK or KAP alone. The regression of PSD vs RAK provided better predictions of PSD than the regression of PSD vs KAP. The partial-pooling (clustered) method yields smaller mean squared errors compared with the complete-pooling method.Conclusion: PSD distributions for interventional radiology procedures are log-normal. Estimates of PSD derived from RAK and KAP jointly are most accurate, followed closely by estimates derived from RAK alone. Estimates of PSD derived from KAP alone are the least accurate. Using a stochastic search approach, it is possible to cluster together certain dissimilar types of procedures to minimize the total error sum of squares.

  8. Radiation dose in coronary angiography and intervention: initial results from the establishment of a multi-centre diagnostic reference level in Queensland public hospitals

    SciTech Connect (OSTI)

    Crowhurst, James A; Whitby, Mark; Thiele, David; Halligan, Toni; Westerink, Adam; Crown, Suzanne; Milne, Jillian

    2014-09-15

    Radiation dose to patients undergoing invasive coronary angiography (ICA) is relatively high. Guidelines suggest that a local benchmark or diagnostic reference level (DRL) be established for these procedures. This study sought to create a DRL for ICA procedures in Queensland public hospitals. Data were collected for all Cardiac Catheter Laboratories in Queensland public hospitals. Data were collected for diagnostic coronary angiography (CA) and single-vessel percutaneous intervention (PCI) procedures. Dose area product (P{sub KA}), skin surface entrance dose (K{sub AR}), fluoroscopy time (FT), and patient height and weight were collected for 3 months. The DRL was set from the 75th percentile of the P{sub KA.} 2590 patients were included in the CA group where the median FT was 3.5 min (inter-quartile range = 2.3–6.1). Median K{sub AR} = 581 mGy (374–876). Median P{sub KA} = 3908 uGym{sup 2} (2489–5865) DRL = 5865 uGym{sup 2}. 947 patients were included in the PCI group where median FT was 11.2 min (7.7–17.4). Median K{sub AR} = 1501 mGy (928–2224). Median P{sub KA} = 8736 uGym{sup 2} (5449–12,900) DRL = 12,900 uGym{sup 2}. This study established a benchmark for radiation dose for diagnostic and interventional coronary angiography in Queensland public facilities.

  9. ABSTRACT: The consequences of baclofen intake on voluntary motor behaviors remain unclear. We studied the effects of single oral doses of

    E-Print Network [OSTI]

    and surface and single motor unit (MU) electromyographic (EMG) activity from the vastus lateralis in 11 AND ELECTROMYOGRAPHIC ACTIVITY FOLLOWING ORAL BACLOFEN T. GEORGE HORNBY, PhD,1 C. J. HECKMAN, PhD,2 RICHARD L. HARVEY

  10. Quantification of absorption, retention and elimination of two different oral doses of vitamin A in Zambian boys using accelerator mass spectrometry

    SciTech Connect (OSTI)

    Aklamati, E K; Mulenga, M; Dueker, S R; Buchholz, B A; Peerson, J M; Kafwembe, E; Brown, K H; Haskell, M J

    2009-10-12

    A recent survey indicated that high-dose vitamin A supplements (HD-VAS) had no apparent effect on vitamin A (VA) status of Zambian children <5 y of age. To explore possible reasons for the lack of response to HD-VAS among Zambian children, we quantified the absorption, retention, and urinary elimination of either a single HDVAS (60 mg) or a smaller dose of stable isotope (SI)-labeled VA (5 mg), which was used to estimate VA pool size, in 3-4 y old Zambian boys (n = 4 for each VA dose). A 25 nCi tracer dose of [{sup 14}C{sub 2}]-labeled VA was co-administered with the HD-VAS or SI-labeled VA, and 24-hr stool and urine samples were collected for 3 and 7 consecutive days, respectively, and 24-hr urine samples at 4 later time points. Accelerator Mass Spectrometry (AMS) was used to measure the cumulative excretion of {sup 14}C in stool and urine 3d after dosing to estimate, respectively, absorption and retention of the VAS and SI-labeled VA. The urinary elimination rate (UER) was estimated by plotting {sup 14}C in urine vs. time, and fitting an exponential equation to the data. Estimates of mean absorption, retention and the UER were 83.8 {+-} 7.1%, 76.3 {+-} 6.7%, and 1.9 {+-} 0.6%/d, respectively, for the HD-VAS and 76.5 {+-} 9.5%, 71.1 {+-} 9.4%, and 1.8 {+-} 1.2%/d, respectively for the smaller dose of SI-labeled VA. Estimates of absorption, retention and the UER did not differ by size of the VA dose administered (P=0.26, 0.40, 0.88, respectively). Estimated absorption and retention were negatively associated with reported fever (P=0.011) and malaria (P =0.010). HD-VAS and SI-labeled VA were adequately absorbed, retained and utilized in apparently healthy Zambian preschool-age boys, although absorption and retention may be affected by recent infections.

  11. An open-label, randomized positron emission tomography (PET) study in healthy male volunteers consisiting of Part A and Part B. Part A: Clinical validation of norepinephrine transporter (NET) PET ligand, (S,S)-[11C]O-methylreboxetine ([11C]MRB) using different doses of oral atomoxetine as NET reuptake inhibitor. Part B: Evaluation of NET occupancy, as measured by [11C]MRB, with multiple dosing regimens of orally administered GSK372475.

    SciTech Connect (OSTI)

    Fowler, Joanna

    2007-08-31

    Results from human studies with the PET radiotracer (S,S)-[(11)C]O-methyl reboxetine ([(11)C](S,S)-MRB), a ligand targeting the norepinephrine transporter (NET), are reported. Quantification methods were determined from test/retest studies, and sensitivity to pharmacological blockade was tested with different doses of atomoxetine (ATX), a drug that binds to the NET with high affinity (K(i)=2-5 nM). METHODS: Twenty-four male subjects were divided into different groups for serial 90-min PET studies with [(11)C](S,S)-MRB to assess reproducibility and the effect of blocking with different doses of ATX (25, 50 and 100 mg, po). Region-of-interest uptake data and arterial plasma input were analyzed for the distribution volume (DV). Images were normalized to a template, and average parametric images for each group were formed. RESULTS: [(11)C](S,S)-MRB uptake was highest in the thalamus (THL) and the midbrain (MBR) [containing the locus coeruleus (LC)] and lowest for the caudate nucleus (CDT). The CDT, a region with low NET, showed the smallest change on ATX treatment and was used as a reference region for the DV ratio (DVR). The baseline average DVR was 1.48 for both the THL and MBR with lower values for other regions [cerebellum (CB), 1.09; cingulate gyrus (CNG) 1.07]. However, more accurate information about relative densities came from the blocking studies. MBR exhibited greater blocking than THL, indicating a transporter density approximately 40% greater than THL. No relationship was found between DVR change and plasma ATX level. Although the higher dose tended to induce a greater decrease than the lower dose for MBR (average decrease for 25 mg=24+/-7%; 100 mg=31+/-11%), these differences were not significant. The different blocking between MBR (average decrease=28+/- 10%) and THL (average decrease=17+/-10%) given the same baseline DVR indicates that the CDT is not a good measure for non-NET binding in both regions. Threshold analysis of the difference between the average baseline DV image and the average blocked image showed the expected NET distribution with the MBR (LC) and hypothalamus>THL>CNG and CB, as well as a significant change in the supplementary motor area. DVR reproducibility for the different brain regions was approximately 10%, but intersubject variability was large. CONCLUSIONS: The highest density of NETs was found in the MBR where the LC is located, followed by THL, whereas the lowest density was found in basal ganglia (lowest in CDT), consistent with the regional localization of NETs in the nonhuman primate brain. While all three doses of ATX were found to block most regions, no significant differences between doses were found for any region, although the average percent change across subjects of the MBR did correlate with ATX dose. The lack of a dose effect could reflect a low signal-to-noise ratio coupled with the possibility that a sufficient number of transporters were blocked at the lowest dose and further differences could not be detected. However, since the lowest (25 mg) dose is less than the therapeutic doses used in children for the treatment of attention-deficit/hyperactivity disorder ( approximately 1.0 mg/kg/day), this would suggest that there may be additional targets for ATX's therapeutic actions.

  12. Bibliography of the Scripps Institution of Oceanography Reference Series 2000

    E-Print Network [OSTI]

    Criqui, Nan P.

    2001-01-01

    SCRIPPS INSTITUTION OF OCEANOGRAPHY REFERENCE SERIES 00-1.Emeritus professor of oceanography, SIO, UCSD. ( OralScripps Institution of Oceanography. March 2000. 80p. 00-5.

  13. Oral Thesis memo_2015

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    FROM: Shalom Shlomo DATE: October 12, 2015 RE: Student Oral Thesis Progress Presentations I have scheduled the oral presentations of the graduate students listed below. These...

  14. Oralidad, narración oral y narración oral escénica

    E-Print Network [OSTI]

    Garzó n Cé spedes, Francisco

    1995-10-01

    escénico y comunicación. Estos Talleres de la Palabra y el Gesto son, entre otros: —Taller Básico de Narración Oral Escénica. —Taller de Perfeccionamiento en NOE / Crítica de repertorio. —Taller de Perfeccionamiento en NOE / Aproximación a la... de la fuente oral o literaria, análisis estuctural del relato, Antropología, Creatividad, Comunicación, Investigación del Folclore, 72 LATIN AMERICAN THEATRE REVIEW Motivación a la Lectura, Movimiento Corporal, Pedagogía, Psico y Neurolingüística...

  15. Reference Materials

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservation of Fe(II) by Carbon-RichProtonAbout Us HanfordReference Materials Reference

  16. Reference Shelf

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservation of Fe(II) by Carbon-RichProtonAbout Us HanfordReference MaterialsReference Shelf

  17. Poroelastic references

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Christina Morency

    2014-12-12

    This file contains a list of relevant references on the Biot theory (forward and inverse approaches), the double-porosity and dual-permeability theory, and seismic wave propagation in fracture porous media, in RIS format, to approach seismic monitoring in a complex fractured porous medium such as Brady?s Geothermal Field.

  18. Poroelastic references

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Christina Morency

    This file contains a list of relevant references on the Biot theory (forward and inverse approaches), the double-porosity and dual-permeability theory, and seismic wave propagation in fracture porous media, in RIS format, to approach seismic monitoring in a complex fractured porous medium such as Brady?s Geothermal Field.

  19. Oakes College: An Oral History

    E-Print Network [OSTI]

    2011-01-01

    Oakes College: An Oral History Blake: That’s unfortunate. I’Oakes College: An Oral History Charland: It took awhile toOakes College: An Oral History with: J. Herman Blake Roberto

  20. Reference Materials

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservation of Fe(II) by Carbon-RichProtonAbout Us Hanford SiteRecoveryWatertheReference

  1. Reference Materials

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservation of Fe(II) by Carbon-RichProtonAbout Us HanfordReference Materials

  2. A less stressful alternative to oral gavage for pharmacological and toxicological studies in mice

    SciTech Connect (OSTI)

    Walker, Mary K.; Boberg, Jason R.; Walsh, Mary T.; Wolf, Valerie; Trujillo, Alisha; Duke, Melissa Skelton; Palme, Rupert

    2012-04-01

    Oral gavage dosing can induce stress and potentially confound experimental measurements, particularly when blood pressure and heart rate are endpoints of interest. Thus, we developed a pill formulation that mice would voluntarily consume and tested the hypothesis that pill dosing would be significantly less stressful than oral gavage. C57Bl/6 male mice were singly housed and on four consecutive days were exposed to an individual walking into the room (week 1, control), a pill being placed into the cage (week 2), and a dose of water via oral gavage (week 3). Blood pressure and heart rate were recorded by radiotelemetry continuously for 5 h after treatment, and feces collected 6–10 h after treatment for analysis of corticosterone metabolites. Both pill and gavage dosing significantly increased mean arterial pressure (MAP) during the first hour, compared to control. However, the increase in MAP was significantly greater after gavage and remained elevated up to 5 h, while MAP returned to normal within 2 h after a pill. Neither pill nor gavage dosing significantly increased heart rate during the first hour, compared to control; however, pill dosing significantly reduced heart rate while gavage significantly increased heart rate 2–5 h post dosing. MAP and heart rate did not differ 24 h after dosing. Lastly, only gavage dosing significantly increased fecal corticosterone metabolites, indicating a systemic stress response via activation of the hypothalamic–pituitary–adrenal axis. These data demonstrated that this pill dosing method of mice is significantly less stressful than oral gavage. -- Highlights: ? Developed a novel oral dosing method using a pill that mice will readily consume. ? Assessed stress by blood pressure, heart rate, and fecal corticosterone metabolites. ? Demonstrated that pill dosing is significantly less stressful than oral gavage.

  3. Terry Koenig Oral History

    E-Print Network [OSTI]

    Koenig, Terry L.; Helmer, Lauren

    2010-11-16

    Oral history interview with Terry Koenig conducted by Lauren Helmer in Lawrence, Kansas, on November 16, 2010. In this interview, Terry Koenig discusses her childhood growing up as a member of the Missouri Synod Lutheran Church, the importance...

  4. Seth Davidson Oral History

    E-Print Network [OSTI]

    Davidson, Seth; Stratton, Emily

    2010-10-22

    Oral history interview with Seth Davidson conducted by Emily Stratton in Lawrence, Kansas, on October 22, 2010. In this interview, Seth Davidson, lead pastor and founder of what is now the non-denominational Vintage Church ...

  5. Leni Salkind Oral History

    E-Print Network [OSTI]

    Salkind, Leni; Miller, Timothy

    2009-11-11

    Oral history interview with Leni Salkind conducted by Timothy Miller in Lawrence, Kansas, on November 11, 2009. In this interview, Leni Salkind describes her experiences as a member of the Jewish community in Lawrence. She ...

  6. Mary Tholen Oral History

    E-Print Network [OSTI]

    Tholen, Mary; Shriner, Clint

    2009-12-10

    Oral history interview with Mary Tholen conducted by Clint Shriner in Kansas City, Missouri, on December 10, 2009. In this interview, Mary Tholen describes her experiences growing up as a member of the Catholic Church, ...

  7. Velda Sloan Oral History

    E-Print Network [OSTI]

    Sloan, Velda; Heidrick, Sarah

    2009-11-09

    Oral history interview with Velda Sloan conducted by Sarah Heidrick in Salina, Kansas, on November 9, 2009. In this interview, Velda Sloan discusses her experiences attending Methodist and Presybterian churches in a variety of locations during...

  8. Pearlena Moore Oral History

    E-Print Network [OSTI]

    Moore, Pearlena; Heidrick, Sarah

    2009-11-14

    Oral history interview with Pearlena Moore conducted by Sarah Heidrick in Hill City, Kansas, on November 14, 2009. In this interview, Pearleena Moore, a member of the Williams Sisters gospel singing group, describes her experiences growing up...

  9. David Nelson Oral History

    E-Print Network [OSTI]

    Nelson, David; Gadd-Nelson, Rachel

    2009-10-31

    Oral history interview with David Nelson conducted by Rachel Gadd-Nelson in Kansas City, Kansas, on October 31, 2009. In this interview, David Nelson discusses his journey from his childhood experiences in the Swedish Lutheran church in Burdick...

  10. Kansas Lawsonians Oral History

    E-Print Network [OSTI]

    Mook, John; Mook, Paula; Hunergaaurd, George; Reeve, Jamie

    2009-12-08

    Oral history interview with John and Paula Mook and George Hunergaaurd conducted by Jamie Reeve in Wichita, Kansas, on December 8, 2009. In this interview, John and Paul Mook and George Hunergaaurd discuss the biography of Alfred Lawson, the history...

  11. Glenn Lindell Oral History

    E-Print Network [OSTI]

    Lindell, Glenn; Caton, Jeffrey

    2009-10-24

    Oral history interview with Glenn Lindell conducted by Jeffrey Caton in Johnson County, Kansas, on October 24, 2009. In this interview, Glen Lindell, pastor emeritus of the Hillcrest Covenant Church in Prairie Village, Kansas, discusses his training...

  12. Anna Manning Oral History

    E-Print Network [OSTI]

    Manning, Anna; Manning, Sean

    2009-11-05

    Oral history interview with Anna Manning conducted by Sean Manning in Overland Park, Kansas, on November 5, 2009. In this interview, Anna Manning discusses the Hispanic ministries in Catholic Churches in Johnson County, Kansas. This interview...

  13. Kahler Wiebe Oral History

    E-Print Network [OSTI]

    Wiebe, Kahler; Roane, Jordan

    2014-01-01

    Oral history interview of Kahler Wiebe conducted by Jordan Roane in Lawrence, Kansas, on November 11, 2014. Kahler is 15 years old and the youngest member of the Wiebe family. The Wiebe family regularly attends Grace Evangelical Presbyterian Church...

  14. Pat Miller Oral History

    E-Print Network [OSTI]

    Miller, Pat; Albin, Tami

    2009-10-28

    Under the Rainbow: Oral Histories of Gay, Lesbian, Bisexual, Transgender, Intersex and Queer People in Kansas Pat Miller Oral History Interviewed by Tami Albin March 21, 2008 http...) for the correct citation style for audio/video interviews or transcripts. Please be sure to include: Narrator’s name e.g. Bill Smith Interviewer’s Name e.g. Tami Albin Date of interview e.g. March 26, 2009 Name of project and location e.g. Under...

  15. ORAL REFERENCE: ICF1001077 MECHANICAL PROPERTIES, ADHESION, AND

    E-Print Network [OSTI]

    Volinsky, Alex A.

    toughness, mechanical properties INTRODUCTION The semiconductor industry is gradually moving from well and Cu interconnects. For the above-mentioned mechanical device stability four material properties toughness. Mechanical properties of thin films often differ from those of the bulk materials. This can

  16. Michael Johnson Oral History

    E-Print Network [OSTI]

    Johnson, Michael; Albin, Tami

    2009-12-16

    support groups or whatever like that and then it just turned into, Well there's Michael Johnson January 4, 2009 5 Under the Rainbow: Oral Histories of GLBTIQ People in Kansas porn online too. (laugh) So it's like—it's like you just kind... stepmother had found my Xanga site as well. Along with that she had found, on his computer, links to porn site—like gay porn Michael Johnson January 4, 2009 7 Under the Rainbow: Oral Histories of GLBTIQ People in Kansas sites, right...

  17. Lin Tongqi : an oral history

    E-Print Network [OSTI]

    Chen, Xin, S.M. Massachusetts Institute of Technology

    2014-01-01

    In this thesis, I explore the life of Professor Lin Tongqi, a well-known scholar of American Chinese studies, by using an oral history methodology. This oral history is named "Suffering and Thinking," and my goal is to ...

  18. Chuck Stanford Oral History

    E-Print Network [OSTI]

    Stanford, Chuck; Bowman, Nathan

    2015-01-01

    Oral history interview with Lama Chuck Stanford, co-founder and director of the Rime Buddhist Center in Kansas City, Missouri. This interview was conducted on June 4, 2015, at a Starbucks near Stanford’s home in Southern Johnson County, Kansas...

  19. Warren Wiebe Oral History

    E-Print Network [OSTI]

    Wiebe, Warren; Roane, Jordan

    2014-01-01

    Oral history interview of Warren Wiebe conducted by Jordan Roane in Lawrence, Kansas, on November 12, 2014. Warren grew up in the small western Kansas town of Hillsboro. Hillsboro is known for its Mennonite community as well as the Mennonite college...

  20. Larry Wren Oral History

    E-Print Network [OSTI]

    Wren, Larry; Stratton, Emily

    2013-06-16

    Oral history interview with Larry Wren conducted by Emily Stratton in Wichita, Kansas, on June 16, 2013. Larry Wren is a long-time member and leader in Pathway Church, and now also serves as Pathway's Café Campus Pastor. Pathway Church is a well...

  1. Professional References Ready Reference E-11

    E-Print Network [OSTI]

    Professional References Ready Reference E-11 College of Engineering, Architecture & Technology College of Engineering, Architecture & Technology Career Services Office ATRC 109E Stillwater, OK 74078 requested to do so. Create a separate sheet entitled "References." Print it on the same high quality papers

  2. Oral Tradition in Historical Research 

    E-Print Network [OSTI]

    Hankins, Rebecca

    2004-01-01

    /plain; charset=windows-1252 Enduring Legacies: Oral Tradition in Historical Research Rebecca HANKINS, C.A., Assistant Professor, Area Studies, Texas A&M University MS5000 TAMU; College Station, Texas 77843-5000 ? HYPERLINK "mailto... African, Middle Eastern, and Asian societies that view oral transmission as an avenue to preserving the history, traditions, genealogical, and cultural legacies of their communities. These cultures have elevated those individuals who are the oral memories...

  3. Shari T. Oral History

    E-Print Network [OSTI]

    T., Shari; Albin, Tami

    2009-12-17

    of mine in St. Louis, she's not gay or bi or anything, but she Shari T February 25, 2009 10 Under the Rainbow: Oral Histories of GLBTIQ People in Kansas would love to go to Pride. She's (laugh) actually ex-Mormon and because of the whole... Proposition 8 thing, she's finally resigning from the church. And that was the camel that broke—the straw that broke the camel's back. Her dad was like a bishop in the Mormon church for years and years and years. Her whole family is very, very Mormon...

  4. Emergency Information Desk Reference

    E-Print Network [OSTI]

    Gopalakrishnan, K.

    Emergency Information Desk Reference ECU Police Department ECU Environmental Health & Safety Revised Feb 2012 #12;Emergency Information Desk Reference 2 INTRODUCTION Emergencies, accidents, and injuries can occur at any time and without warning. ECU has designed this emergency information desk

  5. Extended range radiation dose-rate monitor

    DOE Patents [OSTI]

    Valentine, Kenneth H. (Knoxville, TN)

    1988-01-01

    An extended range dose-rate monitor is provided which utilizes the pulse pileup phenomenon that occurs in conventional counting systems to alter the dynamic response of the system to extend the dose-rate counting range. The current pulses from a solid-state detector generated by radiation events are amplified and shaped prior to applying the pulses to the input of a comparator. The comparator generates one logic pulse for each input pulse which exceeds the comparator reference threshold. These pulses are integrated and applied to a meter calibrated to indicate the measured dose-rate in response to the integrator output. A portion of the output signal from the integrator is fed back to vary the comparator reference threshold in proportion to the output count rate to extend the sensitive dynamic detection range by delaying the asymptotic approach of the integrator output toward full scale as measured by the meter.

  6. Oral Tradition and the Internet

    E-Print Network [OSTI]

    Foley, John Miles

    2010-12-10

    Although the proposition may at first seem counterintuitive, humankind’s oldest and newest technologies of communication are fundamentally homologous. To put it succinctly, oral tradition (OT) and Internet technology (IT) share the core dynamic...

  7. Dorothy Nickel Friesen Oral History

    E-Print Network [OSTI]

    Friesen, Dorothy Nickel; Hobson, Katie

    2015-01-01

    Oral history interview with Dorothy Nickel Friesen conducted by Katie Hobson on July 7, 2015. This interview features the interim pastor at Bethel College Mennonite Church in Newton, Kansas. Questions address Dorothy's experiences as an ordained...

  8. High frequency reference electrode

    DOE Patents [OSTI]

    Kronberg, J.W.

    1994-05-31

    A high frequency reference electrode for electrochemical experiments comprises a mercury-calomel or silver-silver chloride reference electrode with a layer of platinum around it and a layer of a chemically and electrically resistant material such as TEFLON around the platinum covering all but a small ring or halo' at the tip of the reference electrode, adjacent to the active portion of the reference electrode. The voltage output of the platinum layer, which serves as a redox electrode, and that of the reference electrode are coupled by a capacitor or a set of capacitors and the coupled output transmitted to a standard laboratory potentiostat. The platinum may be applied by thermal decomposition to the surface of the reference electrode. The electrode provides superior high-frequency response over conventional electrodes. 4 figs.

  9. High frequency reference electrode

    DOE Patents [OSTI]

    Kronberg, James W. (Aiken, SC)

    1994-01-01

    A high frequency reference electrode for electrochemical experiments comprises a mercury-calomel or silver-silver chloride reference electrode with a layer of platinum around it and a layer of a chemically and electrically resistant material such as TEFLON around the platinum covering all but a small ring or "halo" at the tip of the reference electrode, adjacent to the active portion of the reference electrode. The voltage output of the platinum layer, which serves as a redox electrode, and that of the reference electrode are coupled by a capacitor or a set of capacitors and the coupled output transmitted to a standard laboratory potentiostat. The platinum may be applied by thermal decomposition to the surface of the reference electrode. The electrode provides superior high-frequency response over conventional electrodes.

  10. Derivation of dose conversion factors for tritium

    SciTech Connect (OSTI)

    Killough, G. G.

    1982-03-01

    For a given intake mode (ingestion, inhalation, absorption through the skin), a dose conversion factor (DCF) is the committed dose equivalent to a specified organ of an individual per unit intake of a radionuclide. One also may consider the effective dose commitment per unit intake, which is a weighted average of organ-specific DCFs, with weights proportional to risks associated with stochastic radiation-induced fatal health effects, as defined by Publication 26 of the International Commission on Radiological Protection (ICRP). This report derives and tabulates organ-specific dose conversion factors and the effective dose commitment per unit intake of tritium. These factors are based on a steady-state model of hydrogen in the tissues of ICRP's Reference Man (ICRP Publication 23) and equilibrium of specific activities between body water and other tissues. The results differ by 27 to 33% from the estimate on which ICRP Publication 30 recommendations are based. The report also examines a dynamic model of tritium retention in body water, mineral bone, and two compartments representing organically-bound hydrogen. This model is compared with data from human subjects who were observed for extended periods. The manner of combining the dose conversion factors with measured or model-predicted levels of contamination in man's exposure media (air, drinking water, soil moisture) to estimate dose rate to an individual is briefly discussed.

  11. Optical voltage reference

    DOE Patents [OSTI]

    Rankin, R.; Kotter, D.

    1994-04-26

    An optical voltage reference for providing an alternative to a battery source is described. The optical reference apparatus provides a temperature stable, high precision, isolated voltage reference through the use of optical isolation techniques to eliminate current and impedance coupling errors. Pulse rate frequency modulation is employed to eliminate errors in the optical transmission link while phase-lock feedback is employed to stabilize the frequency to voltage transfer function. 2 figures.

  12. Optical voltage reference

    DOE Patents [OSTI]

    Rankin, Richard (Ammon, ID); Kotter, Dale (Bingham County, ID)

    1994-01-01

    An optical voltage reference for providing an alternative to a battery source. The optical reference apparatus provides a temperature stable, high precision, isolated voltage reference through the use of optical isolation techniques to eliminate current and impedance coupling errors. Pulse rate frequency modulation is employed to eliminate errors in the optical transmission link while phase-lock feedback is employed to stabilize the frequency to voltage transfer function.

  13. Enjebi Island dose assessment

    SciTech Connect (OSTI)

    Robison, W.L.; Conrado, C.L.; Phillips, W.A.

    1987-07-01

    We have updeated the radiological dose assessment for Enjebi Island at Enewetak Atoll using data derived from analysis of food crops grown on Enjebi. This is a much more precise assessment of potential doses to people resettling Enjebi Island than the 1980 assessment in which there were no data available from food crops on Enjebi. Details of the methods and data used to evaluate each exposure pathway are presented. The terrestrial food chain is the most significant potential exposure pathway and /sup 137/Cs is the radionuclide responsible for most of the estimated dose over the next 50 y. The doses are calculated assuming a resettlement date of 1990. The average wholebody maximum annual estimated dose equivalent derived using our diet model is 166 mremy;the effective dose equivalent is 169 mremy. The estimated 30-, 50-, and 70-y integral whole-body dose equivalents are 3.5 rem, 5.1 rem, and 6.2 rem, respectively. Bone-marrow dose equivalents are only slightly higher than the whole-body estimates in each case. The bone-surface cells (endosteal cells) receive the highest dose, but they are a less sensitive cell population and are less sensitive to fatal cancer induction than whole body and bone marrow. The effective dose equivalents for 30, 50, and 70 y are 3.6 rem, 5.3 rem, and 6.6 rem, respectively. 79 refs., 17 figs., 24 tabs

  14. Sandia Energy - Reference Model Documents

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Documents Home Stationary Power Energy Conversion Efficiency Water Power Reference Model Project (RMP) Reference Model Documents Reference Model DocumentsTara Camacho-Lopez2015-05-...

  15. Oral History Editors and Writers for the Stanford Historical Society Oral History Program

    E-Print Network [OSTI]

    Jurafsky, Daniel

    Oral History Editors and Writers for the Stanford Historical Society Oral History Program The Stanford Historical Society's Oral History Program documents the institutional history of the University, publication, dissemination and preservation of the history of the Leland Stanford Junior University

  16. Psoriasis and oral lesions: Multicentric study of oral mucosa diseases italian group (GIPMO)

    E-Print Network [OSTI]

    2012-01-01

    PubMed ] 5. Farley E, Menter A. Psoriasis: Comorbidities andPsoriasis and oral lesions: Multicentric study of orallesions in patients with psoriasis. Med Oral Patol Oral Cir

  17. Application Protocol Reference Architecture Application Protocol Reference Architecture

    E-Print Network [OSTI]

    van Sinderen, Marten

    Application Protocol Reference Architecture 165 Chapter 7 Application Protocol Reference Architecture This chapter proposes an alternative reference architecture for application protocols. The proposed reference architecture consists of the set of possible architectures for application protocols

  18. Neutron dose equivalent meter

    DOE Patents [OSTI]

    Olsher, Richard H. (Los Alamos, NM); Hsu, Hsiao-Hua (Los Alamos, NM); Casson, William H. (Los Alamos, NM); Vasilik, Dennis G. (Los Alamos, NM); Kleck, Jeffrey H. (Menlo Park, CA); Beverding, Anthony (Foster City, CA)

    1996-01-01

    A neutron dose equivalent detector for measuring neutron dose capable of accurately responding to neutron energies according to published fluence to dose curves. The neutron dose equivalent meter has an inner sphere of polyethylene, with a middle shell overlying the inner sphere, the middle shell comprising RTV.RTM. silicone (organosiloxane) loaded with boron. An outer shell overlies the middle shell and comprises polyethylene loaded with tungsten. The neutron dose equivalent meter defines a channel through the outer shell, the middle shell, and the inner sphere for accepting a neutron counter tube. The outer shell is loaded with tungsten to provide neutron generation, increasing the neutron dose equivalent meter's response sensitivity above 8 MeV.

  19. HAZARDOUS WASTE MANAGEMENT REFERENCE

    E-Print Network [OSTI]

    Winfree, Erik

    HAZARDOUS WASTE MANAGEMENT REFERENCE GUIDE Prepared by Environment, Health and Safety Office@caltech.edu http://safety.caltech.edu #12;Hazardous Waste Management Reference Guide Page 2 of 36 TABLE OF CONTENTS Satellite Accumulation Area 9 Waste Accumulation Facility 10 HAZARDOUS WASTE CONTAINER MANAGEMENT Labeling

  20. Reference Hashed Frank Schilder

    E-Print Network [OSTI]

    provides the reader with an introduction to hashing lists and how they can be used for linguistic dam data structure for the representation of discourse referents. A so-called hashing list is employed instead a novel data structure for the representation of discourse referents. A/rushing list t

  1. Technology, safety and costs of decommissioning a reference boiling water reactor power station. Appendices. Volume 2

    SciTech Connect (OSTI)

    Oak, H.D.; Holter, G.M.; Kennedy, W.E. Jr.; Konzek, G.J.

    1980-06-01

    Appendices are presented concerning the evaluations of decommissioning financing alternatives; reference site description; reference BWR facility description; radiation dose rate and concrete surface contamination data; radionuclide inventories; public radiation dose models and calculated maximum annual doses; decommissioning methods; generic decommissioning information; immediate dismantlement details; passive safe storage, continuing care, and deferred dismantlement details; entombment details; demolition and site restoration details; cost estimating bases; public radiological safety assessment details; and details of alternate study bases.

  2. On effective dose for radiotherapy based on doses to nontarget organs and tissues

    SciTech Connect (OSTI)

    Uselmann, Adam J. Thomadsen, Bruce R.

    2015-02-15

    Purpose: The National Council for Radiation Protection and Measurement (NCRP) published estimates for the collective population dose and the mean effective dose to the population of the United States from medical imaging procedures for 1980/1982 and for 2006. The earlier report ignored the effective dose from radiotherapy and the latter gave a cursory discussion of the topic but again did not include it in the population exposure for various reasons. This paper explains the methodology used to calculate the effective dose in due to radiotherapy procedures in the latter NCRP report and revises the values based on more detailed modeling. Methods: This study calculated the dose to nontarget organs from radiotherapy for reference populations using CT images and published peripheral dose data. Results: Using International Commission on Radiological Protection (ICRP) 60 weighting factors, the total effective dose to nontarget organs in radiotherapy patients is estimated as 298 ± 194 mSv per patient, while the U.S. population effective dose is 0.939 ± 0.610 mSv per person, with a collective dose of 283?000 ± 184?000 person Sv per year. Using ICRP 103 weighting factors, the effective dose is 281 ± 183 mSv per patient, 0.887 ± 0.577 mSv per person in the U.S., and 268?000 ± 174?000 person Sv per year. The uncertainty in the calculations is largely governed by variations in patient size, which was accounted for by considering a range of patient sizes and taking the average treatment site to nontarget organ distance. Conclusions: The methods used to estimate the effective doses from radiotherapy used in NCRP Report No. 160 have been explained and the values updated.

  3. Value of Information References

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Morency, Christina

    2014-12-12

    This file contains a list of relevant references on value of information (VOI) in RIS format. VOI provides a quantitative analysis to evaluate the outcome of the combined technologies (seismology, hydrology, geodesy) used to monitor Brady's Geothermal Field.

  4. Value of Information References

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Morency, Christina

    This file contains a list of relevant references on value of information (VOI) in RIS format. VOI provides a quantitative analysis to evaluate the outcome of the combined technologies (seismology, hydrology, geodesy) used to monitor Brady's Geothermal Field.

  5. Precision displacement reference system

    DOE Patents [OSTI]

    Bieg, Lothar F. (Albuquerque, NM); Dubois, Robert R. (Albuquerque, NM); Strother, Jerry D. (Edgewood, NM)

    2000-02-22

    A precision displacement reference system is described, which enables real time accountability over the applied displacement feedback system to precision machine tools, positioning mechanisms, motion devices, and related operations. As independent measurements of tool location is taken by a displacement feedback system, a rotating reference disk compares feedback counts with performed motion. These measurements are compared to characterize and analyze real time mechanical and control performance during operation.

  6. The Greenhouse Culture Oral History

    E-Print Network [OSTI]

    Scholz, Jared; Sipp, Kalah; Stratton, Emily

    2013-06-26

    Oral history interview with Jared Scholz and Kalah Sipp conducted by Emily Stratton in Lawrence, Kansas, on June 26, 2013. Jared Scholz is the founder and Senior Pastor of The Greenhouse Culture; Kalah Sipp is The Greenhouse Culture’s Administrative...

  7. UW-Madison Oral History Project Oral History #644 Denice Denton

    E-Print Network [OSTI]

    Sheridan, Jennifer

    UW-Madison Oral History Project Oral History #644 ­ Denice Denton Narrator: Coleman, Joyce Fine (9/11/09) Please note: This oral history and transcript is protected by the 1978 copyright law extensive segments of this interview/transcript must be obtained from the UW-Madison Oral History Program

  8. Aluminum reference electrode

    DOE Patents [OSTI]

    Sadoway, Donald R. (Belmont, MA)

    1988-01-01

    A stable reference electrode for use in monitoring and controlling the process of electrolytic reduction of a metal. In the case of Hall cell reduction of aluminum, the reference electrode comprises a pool of molten aluminum and a solution of molten cryolite, Na.sub.3 AlF.sub.6, wherein the electrical connection to the molten aluminum does not contact the highly corrosive molten salt solution. This is accomplished by altering the density of either the aluminum (decreasing the density) or the electrolyte (increasing the density) so that the aluminum floats on top of the molten salt solution.

  9. Aluminum reference electrode

    DOE Patents [OSTI]

    Sadoway, D.R.

    1988-08-16

    A stable reference electrode is described for use in monitoring and controlling the process of electrolytic reduction of a metal. In the case of Hall cell reduction of aluminum, the reference electrode comprises a pool of molten aluminum and a solution of molten cryolite, Na[sub 3]AlF[sub 6], wherein the electrical connection to the molten aluminum does not contact the highly corrosive molten salt solution. This is accomplished by altering the density of either the aluminum (decreasing the density) or the electrolyte (increasing the density) so that the aluminum floats on top of the molten salt solution. 1 fig.

  10. Multifunctional reference electrode

    DOE Patents [OSTI]

    Redey, L.; Vissers, D.R.

    1981-12-30

    A multifunctional, low mass reference electrode of a nickel tube, thermocouple means inside the nickel tube electrically insulated therefrom for measuring the temperature thereof, a housing surrounding the nickel tube, an electrolyte having a fixed sulfide ion activity between the housing and the outer surface of the nickel tube forming the nickel/nickel sulfide/sulfide half-cell are described. An ion diffusion barrier is associated with the housing in contact with the electrolyte. Also disclosed is a cell using the reference electrode to measure characteristics of a working electrode.

  11. ORISE: Dose modeling and assessments

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Dose modeling and assessments The Oak Ridge Institute for Science and Education (ORISE) offers dose modeling and assessment services to demonstrate that federal andor state...

  12. Grant Reference Lead / Sole

    E-Print Network [OSTI]

    Rank Overall Score Grant Reference Lead / Sole Grant Grant Holder Research Organisation Project of Birmingham Controls on Soil Carbon Export revealed by Novel Tracers on multiple timescales (SCENT) Standard Grant DEC12 8 8 NE/K011871/1 N Melanie Leng NERC British Geological Survey A 500,000-year environmental

  13. External Dose Estimates from

    E-Print Network [OSTI]

    ; - calculated separately for the most important radionuclides produced in nuclear weapons tests. Those would averages for all tests. 2. Provide a list of references regarding: (1) the history of nuclear weapons

  14. Dose Reduction Techniques

    SciTech Connect (OSTI)

    WAGGONER, L.O.

    2000-05-16

    As radiation safety specialists, one of the things we are required to do is evaluate tools, equipment, materials and work practices and decide whether the use of these products or work practices will reduce radiation dose or risk to the environment. There is a tendency for many workers that work with radioactive material to accomplish radiological work the same way they have always done it rather than look for new technology or change their work practices. New technology is being developed all the time that can make radiological work easier and result in less radiation dose to the worker or reduce the possibility that contamination will be spread to the environment. As we discuss the various tools and techniques that reduce radiation dose, keep in mind that the radiological controls should be reasonable. We can not always get the dose to zero, so we must try to accomplish the work efficiently and cost-effectively. There are times we may have to accept there is only so much you can do. The goal is to do the smart things that protect the worker but do not hinder him while the task is being accomplished. In addition, we should not demand that large amounts of money be spent for equipment that has marginal value in order to save a few millirem. We have broken the handout into sections that should simplify the presentation. Time, distance, shielding, and source reduction are methods used to reduce dose and are covered in Part I on work execution. We then look at operational considerations, radiological design parameters, and discuss the characteristics of personnel who deal with ALARA. This handout should give you an overview of what it takes to have an effective dose reduction program.

  15. OSH technical reference manual

    SciTech Connect (OSTI)

    Not Available

    1993-11-01

    In an evaluation of the Department of Energy (DOE) Occupational Safety and Health programs for government-owned contractor-operated (GOCO) activities, the Department of Labor`s Occupational Safety and Health Administration (OSHA) recommended a technical information exchange program. The intent was to share written safety and health programs, plans, training manuals, and materials within the entire DOE community. The OSH Technical Reference (OTR) helps support the secretary`s response to the OSHA finding by providing a one-stop resource and referral for technical information that relates to safe operations and practice. It also serves as a technical information exchange tool to reference DOE-wide materials pertinent to specific safety topics and, with some modification, as a training aid. The OTR bridges the gap between general safety documents and very specific requirements documents. It is tailored to the DOE community and incorporates DOE field experience.

  16. Reference Radiation for Cosmic Rays in RBE Research 

    E-Print Network [OSTI]

    Feng, Shaoyong

    2011-10-21

    effectiveness relative to a specific radiation is usually used. For low energy heavy ions and neutrons 250 keV photons are usually used for the reference radiation but their depth dose distribution is very different from that for cosmic rays. In this research...

  17. An Oral History of the Justice for Janitors Movement: On Trauma, Central America, and the Undocumented

    E-Print Network [OSTI]

    Gomez, Andrew

    2015-01-01

    Thomson (Eds. ), The oral history reader (pp. 495-505). New2015). Recording oral history: A guide for the humanitieshealing’: Trauma, oral history and regeneration. Oral

  18. Development of Oral Fomulation of SCV-07 for Use in Tuberculosis

    SciTech Connect (OSTI)

    2007-11-16

    An evaluation of the immunomodulatory peptide SCV-07 was conducted as a possible therapeutic treatment for tuberculosis. This evaluation included mouse models, clinical trials and various forms of the drug such as liquid injection and development of an oral pill. It was found that SCV-07 significantly increased the survival rate of animals infected with lethal doses of Mycobacterium bovis. It enhanced the functional activity of macrophages in a dose-dependent fashion. The combination of SCV-07 with bacteriostatic drugs, such as izoniazid, was particularly effective. Phase II clinical trials in a TB clinic demonstrated that the usage of the injection form of SCV-07 for lung TB treatment in combination with standard chemotherapy decreased the quantity of patients with positive sputum assays for Mycobacteria, promoted healing of cavities in lungs, stabilized parameters of cell immunity, and resulted in a significant improvement in the general condition of patients. Clinical trials results of the oral drug form are still being evaluated.

  19. Appendix A: Reference case

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustments (Billion Cubic Feet)Decade Year-0ProvedDecade2,948 2,724 2,570Month PreviousDry4,645 8244 Reference

  20. Appendix A: Reference case

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustments (Billion Cubic Feet)Decade Year-0ProvedDecade2,948 2,724 2,570Month PreviousDry4,645 8244 Reference6

  1. Appendix A: Reference case

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustments (Billion Cubic Feet)Decade Year-0ProvedDecade2,948 2,724 2,570Month PreviousDry4,645 8244 Reference64

  2. Appendix A: Reference case

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustments (Billion Cubic Feet)Decade Year-0ProvedDecade2,948 2,724 2,570Month PreviousDry4,645 82444 Reference

  3. Appendix A: Reference case

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustments (Billion Cubic Feet)Decade Year-0ProvedDecade2,948 2,724 2,570Month PreviousDry4,645 82444 Reference6

  4. Manufacturing Energy and Carbon Footprint References | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    References Manufacturing Energy and Carbon Footprint References footprintreferences.pdf More Documents & Publications 2010 Manufacturing Energy and Carbon Footprints: References...

  5. Coal data: A reference

    SciTech Connect (OSTI)

    Not Available

    1995-02-01

    This report, Coal Data: A Reference, summarizes basic information on the mining and use of coal, an important source of energy in the US. This report is written for a general audience. The goal is to cover basic material and strike a reasonable compromise between overly generalized statements and detailed analyses. The section ``Supplemental Figures and Tables`` contains statistics, graphs, maps, and other illustrations that show trends, patterns, geographic locations, and similar coal-related information. The section ``Coal Terminology and Related Information`` provides additional information about terms mentioned in the text and introduces some new terms. The last edition of Coal Data: A Reference was published in 1991. The present edition contains updated data as well as expanded reviews and additional information. Added to the text are discussions of coal quality, coal prices, unions, and strikes. The appendix has been expanded to provide statistics on a variety of additional topics, such as: trends in coal production and royalties from Federal and Indian coal leases, hours worked and earnings for coal mine employment, railroad coal shipments and revenues, waterborne coal traffic, coal export loading terminals, utility coal combustion byproducts, and trace elements in coal. The information in this report has been gleaned mainly from the sources in the bibliography. The reader interested in going beyond the scope of this report should consult these sources. The statistics are largely from reports published by the Energy Information Administration.

  6. Tank characterization reference guide

    SciTech Connect (OSTI)

    De Lorenzo, D.S.; DiCenso, A.T.; Hiller, D.B.; Johnson, K.W.; Rutherford, J.H.; Smith, D.J. [Los Alamos Technical Associates, Kennewick, WA (United States); Simpson, B.C. [Westinghouse Hanford Co., Richland, WA (United States)

    1994-09-01

    Characterization of the Hanford Site high-level waste storage tanks supports safety issue resolution; operations and maintenance requirements; and retrieval, pretreatment, vitrification, and disposal technology development. Technical, historical, and programmatic information about the waste tanks is often scattered among many sources, if it is documented at all. This Tank Characterization Reference Guide, therefore, serves as a common location for much of the generic tank information that is otherwise contained in many documents. The report is intended to be an introduction to the issues and history surrounding the generation, storage, and management of the liquid process wastes, and a presentation of the sampling, analysis, and modeling activities that support the current waste characterization. This report should provide a basis upon which those unfamiliar with the Hanford Site tank farms can start their research.

  7. Nuclear Science References Database

    E-Print Network [OSTI]

    B. Pritychenko; E. B?ták; B. Singh; J. Totans

    2014-07-08

    The Nuclear Science References (NSR) database together with its associated Web interface, is the world's only comprehensive source of easily accessible low- and intermediate-energy nuclear physics bibliographic information for more than 210,000 articles since the beginning of nuclear science. The weekly-updated NSR database provides essential support for nuclear data evaluation, compilation and research activities. The principles of the database and Web application development and maintenance are described. Examples of nuclear structure, reaction and decay applications are specifically included. The complete NSR database is freely available at the websites of the National Nuclear Data Center http://www.nndc.bnl.gov/nsr and the International Atomic Energy Agency http://www-nds.iaea.org/nsr.

  8. The Oral History Project The Vietnam Archive

    E-Print Network [OSTI]

    Rock, Chris

    The Oral History Project The Vietnam Archive Texas Tech University - Lubbock, TX Legal Disclosure The purpose of the Oral History Project of the Vietnam Archive at Texas Tech University is to gather participation from anyone who experienced the Vietnam War, whether in Southeast Asia, in the United States

  9. Hanford Environmental Dose Reconstruction Project

    SciTech Connect (OSTI)

    Cannon, S.D.; Finch, S.M.

    1992-10-01

    The objective of the Hanford Environmental Dose Reconstruction (HEDR) Project is to estimate the radiation doses that individuals and populations could have received from nuclear operations at Hanford since 1944. The independent Technical Steering Panel (TSP) provides technical direction. The project is divided into the following technical tasks. These tasks correspond to the path radionuclides followed from release to impact on humans (dose estimates):Source Terms, Environmental Transport, Environmental Monitoring Data, Demography, Food Consumption, and Agriculture, and Environmental Pathways and Dose Estimates.

  10. Sensor Characteristics Reference Guide

    SciTech Connect (OSTI)

    Cree, Johnathan V.; Dansu, A.; Fuhr, P.; Lanzisera, Steven M.; McIntyre, T.; Muehleisen, Ralph T.; Starke, M.; Banerjee, Pranab; Kuruganti, T.; Castello, C.

    2013-04-01

    The Buildings Technologies Office (BTO), within the U.S. Department of Energy (DOE), Office of Energy Efficiency and Renewable Energy (EERE), is initiating a new program in Sensor and Controls. The vision of this program is: • Buildings operating automatically and continuously at peak energy efficiency over their lifetimes and interoperating effectively with the electric power grid. • Buildings that are self-configuring, self-commissioning, self-learning, self-diagnosing, self-healing, and self-transacting to enable continuous peak performance. • Lower overall building operating costs and higher asset valuation. The overarching goal is to capture 30% energy savings by enhanced management of energy consuming assets and systems through development of cost-effective sensors and controls. One step in achieving this vision is the publication of this Sensor Characteristics Reference Guide. The purpose of the guide is to inform building owners and operators of the current status, capabilities, and limitations of sensor technologies. It is hoped that this guide will aid in the design and procurement process and result in successful implementation of building sensor and control systems. DOE will also use this guide to identify research priorities, develop future specifications for potential market adoption, and provide market clarity through unbiased information

  11. Standardized radiological dose evaluations

    SciTech Connect (OSTI)

    Peterson, V.L.; Stahlnecker, E.

    1996-05-01

    Following the end of the Cold War, the mission of Rocky Flats Environmental Technology Site changed from production of nuclear weapons to cleanup. Authorization baseis documents for the facilities, primarily the Final Safety Analysis Reports, are being replaced with new ones in which accident scenarios are sorted into coarse bins of consequence and frequency, similar to the approach of DOE-STD-3011-94. Because this binning does not require high precision, a standardized approach for radiological dose evaluations is taken for all the facilities at the site. This is done through a standard calculation ``template`` for use by all safety analysts preparing the new documents. This report describes this template and its use.

  12. Optical probe with reference fiber

    DOE Patents [OSTI]

    Da Silva, Luiz B. (Danville, CA); Chase, Charles L. (Dublin, CA)

    2006-03-14

    A system for characterizing tissue includes the steps of generating an emission signal, generating a reference signal, directing the emission signal to and from the tissue, directing the reference signal in a predetermined manner relative to the emission signal, and using the reference signal to compensate the emission signal. In one embodiment compensation is provided for fluctuations in light delivery to the tip of the probe due to cable motion.

  13. FAQS Reference Guide – Construction Management

    Broader source: Energy.gov [DOE]

    This reference guide addresses the competency statements in the March 2004 edition of DOE-STD-1180-2004, Construction Management Functional Area Qualification Standard.

  14. FAQS Reference Guide – Industrial Hygiene

    Broader source: Energy.gov [DOE]

    This reference guide addresses the competency statements in the November 2007 edition of DOE-STD-1138-2007, Industrial Hygiene Functional Area Qualification Standard.

  15. FAQS Reference Guide – Emergency Management

    Office of Energy Efficiency and Renewable Energy (EERE)

    This reference guide addresses the competency statements in the January 2004 edition of DOE-STD-1177-2004, Emergency Management Functional Area Qualification Standard.

  16. FAQS Reference Guide- Chemical Processing

    Office of Energy Efficiency and Renewable Energy (EERE)

    This reference guide addresses the competency statements in the February 2010 edition of DOE-STD-1176-2010, Chemical Processing Functional Area Qualification Standard.

  17. FAQS Reference Guide – Environmental Compliance

    Office of Energy Efficiency and Renewable Energy (EERE)

    This reference guide addresses the competency statements in the June 2011 edition of DOE-STD-1156-2011, Environmental Compliance Functional Area Qualification Standard.

  18. Rutgers Newark Oral History Project Intern Job Description

    E-Print Network [OSTI]

    Delgado, Mauricio

    uses cutting-edge technology to bring groundbreaking oral history collections to a worldwide audienceRutgers Newark Oral History Project Intern Job Description The Rutgers Newark Oral History Project-American Oral History Collection. Interns will be trained on the InterClipper software program to segment

  19. Ris Energy Report 5 References References for Chapter 3

    E-Print Network [OSTI]

    Risø Energy Report 5 References References for Chapter 3 1. UNEP. (2006). Background paper for the ministerial-level consultations on energy and environment for development. Ninth special session energy outlook 2005. Paris: IEA. 3. IEA. (2003). World energy investment outlook. Paris: IEA. 4. World

  20. Ris Energy Report 6 References Reference list for Chapter 3

    E-Print Network [OSTI]

    Risø Energy Report 6 References Reference list for Chapter 3 1. European Commission. (2007). Communication from the Commis- sion to the European Council and the European Parliament ­ An energy policy of the Brussels European Council 8/9 March 2007. Brussels. (7224/1/07 Rev. 1). 3. Danish Energy authority. (2007

  1. Rebekah Foster-Terry Oral History

    E-Print Network [OSTI]

    Foster-Terry, Rebekah; Meador, Stephanie Rae

    2009-01-01

    Oral history interview with Reverend Rebekah Foster-Terry conducted by Stephanie Meador in 2009. In this interview, Rev. Foster-Terry, pastor of the Victory Tabernacle Church in Topeka, Kansas, discusses the history of the church and her family...

  2. Oral Vowel Reduction in Brazilian Portuguese

    E-Print Network [OSTI]

    Nobre, Maria Alzira; Ingemann, Frances

    1983-01-01

    In Brazilian Portuguese, there are at least two types of unstressed syllables: pretonic and final. Phonologically, this is shown by the fact that the system of 7 phonemic oral vowels in stressed syllables is decreased to ...

  3. 2566 IEEE TRANSACTIONS ON NUCLEAR SCIENCE, VOL. 55, NO. 5, OCTOBER 2008 Virtual Colonoscopy Screening With Ultra Low-Dose

    E-Print Network [OSTI]

    with normal dose scans at 100 mAs levels. The simulated noisy sinogram or projection data were first processed by a Karhunen-Loève domain penalized weighted least-squares (KL-PWLS) restoration method and then reconstructed lumen was constructed and navigated by a VC system after electronic colon cleansing of the orally

  4. Archived Reference Building Type: Warehouse

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the commercial reference building models for existing buildings constructed in or after 1980, organized by building type and location. A summary of building types and climate zones is available for reference. Current versions are also available.

  5. Archived Reference Building Type: Warehouse

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the commercial reference building models for existing buildings constructed before 1980, organized by building type and location. A summary ofbuilding types and climate zones is available for reference. Current versions are also available.

  6. Disposition of clorazepate in dogs after single- and multiple-dose oral administration 

    E-Print Network [OSTI]

    Forrester, Sharon Dru

    1989-01-01

    . vii TABLE OF CONTENTS ABSTRACT. DEDICATION, ACKNOWLEDGEMENTS. TABLE OF CONTENTS. LIST OF TABLES. . LIST OF FIGURES. INTRODUCTION. REVIEN OF THE LITERATURE Pathophysiology of Epilepsy. Canine Epilepsy. Treatment of Epilepsy. Pharmacology... of clorazepate (2 mg/kg of body weight every 12 hours for 21 days) to 7 healthy dogs. . 27 28 INTRODUCTION Epilepsy, recurrent seizures without concomitant underlying disease, affects approximately 1% of the canine population. I Anticonvulsant therapy...

  7. Plasma concentration of glucosamine and chondroitin sulfate in horses following an oral dose 

    E-Print Network [OSTI]

    Welch, Courtney Ann

    2006-04-12

    This study was conducted to study absorption of glucosamine and chondroitin sulfate and to measure any changes in blood concentration of these compounds following feeding them to horses in different amounts. Six mature ...

  8. Sandia Energy - Technical Reference for Hydrogen Compatibility...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Technical Reference for Hydrogen Compatibility of Materials Home Transportation Energy Hydrogen Materials & Components Compatibility Technical Reference for Hydrogen Compatibility...

  9. Dental dose and image quality surveys using optically stimulated luminescence 

    E-Print Network [OSTI]

    Handley, Stephen Michael

    2006-04-12

    these results and mailing back a report of the findings. 42 SUMMARY AND CONCLUSIONS HVL calculations were performed to establish a means to help further characterize the x-ray beam energy spectrum emerging from a dental x-ray machine. Many older... properties of direct exposure and screen-film imaging systems. Dentomaxillofac. Radiology 18:12-14; 1989 Martin, JE. Physics for radiation protection. New York: John Wiley & Sons; 2000 Napier ID. Reference doses for dental radiography. British Dental...

  10. Site-Specific Reference Person Parameters and Derived Concentration Standards for the Savannah River Site

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Stone, Daniel K.; Savannah River Site; Higley, Kathryn A.; Jannik, G. Timothy

    2014-05-01

    The U.S. Department of Energy Order 458.1 states that the compliance with the 1 mSv annual dose constraint to a member of the public may be demonstrated by calculating dose to the maximally exposed individual (MEI) or to a representative person. Historically, the MEI concept was used for dose compliance at the Savannah River Site (SRS) using adult dose coefficients and adult male usage parameters. For future compliance, SRS plans to use the representative person concept for dose estimates to members of the public. The representative person dose will be based on the reference person dose coefficients from the U.S.more »DOE Derived Concentration Technical Standard and on usage parameters specific to SRS for the reference and typical person. Usage parameters and dose coefficients were determined for inhalation, ingestion and external exposure pathways. The parameters for the representative person were used to calculate and tabulate SRS-specific derived concentration standards (DCSs) for the pathways not included in DOE-STD-1196-2011.« less

  11. Site-Specific Reference Person Parameters and Derived Concentration Standards for the Savannah River Site

    SciTech Connect (OSTI)

    Stone, Daniel K.; Higley, Kathryn A.; Jannik, G. Timothy

    2014-05-01

    The U.S. Department of Energy Order 458.1 states that the compliance with the 1 mSv annual dose constraint to a member of the public may be demonstrated by calculating dose to the maximally exposed individual (MEI) or to a representative person. Historically, the MEI concept was used for dose compliance at the Savannah River Site (SRS) using adult dose coefficients and adult male usage parameters. For future compliance, SRS plans to use the representative person concept for dose estimates to members of the public. The representative person dose will be based on the reference person dose coefficients from the U.S. DOE Derived Concentration Technical Standard and on usage parameters specific to SRS for the reference and typical person. Usage parameters and dose coefficients were determined for inhalation, ingestion and external exposure pathways. The parameters for the representative person were used to calculate and tabulate SRS-specific derived concentration standards (DCSs) for the pathways not included in DOE-STD-1196-2011.

  12. Cerebrospinal fluid concentrations of N-acetylcysteine after oral administration in Parkinson's disease

    E-Print Network [OSTI]

    2015-01-01

    of N-acetylcysteine after oral administration in Parkinson'sace- tylcysteine after oral administration: phase I trial inof N-acetylcysteine after oral administration in Parkinson's

  13. SAM Photovoltaic Model Technical Reference

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    SAM Photovoltaic Model Technical Reference P. Gilman National Renewable Energy Laboratory Technical Report NRELTP-6A20-64102 May 2015 NREL is a national laboratory of the U.S....

  14. Emergency Preparedness Desk Reference Manual

    E-Print Network [OSTI]

    Patzek, Tadeusz W.

    Emergency Preparedness Desk Reference Manual Important Phone Numbers Medical Emergencies / Hazardous Material Fire Emergencies Vehicle Accidents Evacuation Weather Emergencies Building/System Problem or Failure Threat of Violence Terrorism Interpersonal Emergencies Next Page >>> #12;Important Phone Numbers

  15. FAQS Reference Guide – Occupational Safety

    Broader source: Energy.gov [DOE]

    This reference guide has been developed to address the competency statements in the July 2011 version of DOE-STD-1160-2011, Occupational Safety Functional Area Qualification Standard.

  16. Safeguards and Security Program References

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2005-08-26

    The manual establishes definitions for terms related to the Department of Energy Safeguards and Security (S&S) Program and includes lists of references and acronyms/abbreviations applicable to S&S Program directives. Cancels the Safeguards and Security Glossary of Terms, dated 12-18-95. Current Safeguards and Security Program References can also be found at Safeguards and Security Policy Information Resource (http://pir.pnl.gov/)

  17. Savannah River Site dose control

    SciTech Connect (OSTI)

    Smith, L.S.

    1992-06-01

    Health physicists from the Brookhaven National Laboratory (BNL) visited the Savannah River Site (SRS) as one of 12 facilities operated by the Department of Energy (DOE) contractors with annual collective dose equivalents greater than 100 person-rem (100 person-cSv). Their charter was to review, evaluate and summarize as low as reasonably achievable (ALARA) techniques, methods and practices as implemented. This presentation gives an overview of the two selected ALARA practices implemented at the SRS: Administrative Exposure Limits and Goal Setting. These dose control methods are used to assure that individual and collective occupational doses are ALARA and within regulatory limits.

  18. Determination of the approximate relative biological effectiveness (RBE) of fast neutrons, utilizing the oral mucosa of dogs as the biological indicator 

    E-Print Network [OSTI]

    Roberts, Royce Elisha

    1975-01-01

    as well as the total radiation intensity (total dose and fractionation scheme). The oral mucosa lends itself to direct visual1zation and coupled with its predictable response to radia- tion has frequently been used as an indicator for irradiated tis.../10 of the total dose delivered (ie, 400 and 425 rads, respectively). The dose rate for the Cobalt-60 treatments was approximately 43 rads/minute, and the treatment field was 4 X 6 cm for all 4 dogs. The source-skin distance (SSD) was 80 cm. (See Table 1...

  19. Hanford Environmental Dose Reconstruction Project

    SciTech Connect (OSTI)

    McMakin, A.H.; Cannon, S.D.; Finch, S.M.

    1992-07-01

    The objective of the Hanford Environmental Dose Reconstruction (HEDR) Project is to estimate the radiation doses that individuals and populations could have received from nuclear operations at Hanford since 1944. The TSP consists of experts in environmental pathways, epidemiology, surface-water transport, ground-water transport, statistics, demography, agriculture, meteorology, nuclear engineering, radiation dosimetry, and cultural anthropology. Included are appointed technical members representing the states of Oregon, Washington, and Idaho, a representative of Native American tribes, and an individual representing the public. The project is divided into the following technical tasks. These tasks correspond to the path radionuclides followed from release to impact on humans (dose estimates): Source terms, environmental transport, environmental monitoring data, demography, food consumption, and agriculture, and environmental pathways and dose estimates. Progress is discussed.

  20. REFERENCES

    E-Print Network [OSTI]

    2008-08-23

    Mechanism of Fluid Displacement in Sands. Trans. Am. Inst. Min. Metall. Eng.,. 146: 107-116. Chaudhari, N.M., 1971. An Improved Numerical Technique for ...

  1. REFERENCES

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5 United States Code (U.S.C.) Section 552a. . b. P.L. 104-106, Division E, Clinger Cohen Act (CCA) (formerly Information Technology Management Reform Act of 1996. c. P.L....

  2. SITE SPECIFIC REFERENCE PERSON PARAMETERS AND DERIVED CONCENTRATION STANDARDS FOR THE SAVANNAH RIVER SITE

    SciTech Connect (OSTI)

    Jannik, T.

    2013-03-14

    The purpose of this report is twofold. The first is to develop a set of behavioral parameters for a reference person specific for the Savannah River Site (SRS) such that the parameters can be used to determine dose to members of the public in compliance with Department of Energy (DOE) Order 458.1 “Radiation Protection of the Public and the Environment.” A reference person is a hypothetical, gender and age aggregation of human physical and physiological characteristics arrived at by international consensus for the purpose of standardizing radiation dose calculations. DOE O 458.1 states that compliance with the annual dose limit of 100 mrem (1 mSv) to a member of the public may be demonstrated by calculating the dose to the maximally exposed individual (MEI) or to a representative person. Historically, for dose compliance, SRS has used the MEI concept, which uses adult dose coefficients and adult male usage parameters. Beginning with the 2012 annual site environmental report, SRS will be using the representative person concept for dose compliance. The dose to a representative person will be based on 1) the SRS-specific reference person usage parameters at the 95th percentile of appropriate national or regional data, which are documented in this report, 2) the reference person (gender and age averaged) ingestion and inhalation dose coefficients provided in DOE Derived Concentration Technical Standard (DOE-STD-1196-2011), and 3) the external dose coefficients provided in the DC_PAK3 toolbox. The second purpose of this report is to develop SRS-specific derived concentration standards (DCSs) for all applicable food ingestion pathways, ground shine, and water submersion. The DCS is the concentration of a particular radionuclide in water, in air, or on the ground that results in a member of the public receiving 100 mrem (1 mSv) effective dose following continuous exposure for one year. In DOE-STD-1196-2011, DCSs were developed for the ingestion of water, inhalation of air and submersion in air pathways, only. These DCSs are required by DOE O 458.1 to be used at all DOE sites in the design and conduct of radiological environmental protection programs. In this report, DCSs for the following additional pathways were considered and documented: ingestion of meat, dairy, grains, produce (fruits and vegetables), seafood, submersion in water and ground shine. These additional DCSs were developed using the same methods as in DOE-STD-1196-2011 and will be used at SRS, where appropriate, as screening and reference values.

  3. Weldon Spring historical dose estimate

    SciTech Connect (OSTI)

    Meshkov, N.; Benioff, P.; Wang, J.; Yuan, Y.

    1986-07-01

    This study was conducted to determine the estimated radiation doses that individuals in five nearby population groups and the general population in the surrounding area may have received as a consequence of activities at a uranium processing plant in Weldon Spring, Missouri. The study is retrospective and encompasses plant operations (1957-1966), cleanup (1967-1969), and maintenance (1969-1982). The dose estimates for members of the nearby population groups are as follows. Of the three periods considered, the largest doses to the general population in the surrounding area would have occurred during the plant operations period (1957-1966). Dose estimates for the cleanup (1967-1969) and maintenance (1969-1982) periods are negligible in comparison. Based on the monitoring data, if there was a person residing continually in a dwelling 1.2 km (0.75 mi) north of the plant, this person is estimated to have received an average of about 96 mrem/yr (ranging from 50 to 160 mrem/yr) above background during plant operations, whereas the dose to a nearby resident during later years is estimated to have been about 0.4 mrem/yr during cleanup and about 0.2 mrem/yr during the maintenance period. These values may be compared with the background dose in Missouri of 120 mrem/yr.

  4. Virtual Alternative to the Oral Examination for Emergency Medicine Residents

    E-Print Network [OSTI]

    2015-01-01

    McGrath et al. A Virtual Alternative to the Oral Examinationexamination is a feasible alternative to the traditionalR esearch Virtual Alternative to the Oral Examination for

  5. No more periods? Oral contraception and menstrual suppression 

    E-Print Network [OSTI]

    Gunson, Dr Jessie

    Oral contraception, or ‘The Pill’, is widely used by women to control how often they have a period. In many countries using oral contraception in this way has remained unofficial practice. However, in 2003 the first FDA ...

  6. Fast Reference-Based MRI

    E-Print Network [OSTI]

    Weizman, Lior; Ben-Basaht, Dafna

    2015-01-01

    In many clinical MRI scenarios, existing imaging information can be used to significantly shorten acquisition time or to improve Signal to Noise Ratio (SNR). In some cases, a previously acquired image can serve as a reference image, that may exhibit similarity to the image being acquired. Examples include similarity between adjacent slices in high resolution MRI, similarity between various contrasts in the same scan and similarity between different scans of the same patient. In this paper we present a general framework for utilizing reference images for fast MRI. We take into account that the reference image may exhibit low similarity with the acquired image and develop an iterative weighted approach for reconstruction, which tunes the weights according to the degree of similarity. Experiments demonstrate the performance of the method in three different clinical MRI scenarios: SNR improvement in high resolution brain MRI, utilizing similarity between T2-weighted and fluid-attenuated inversion recovery (FLAIR)...

  7. Thesis Oral Facts and Reasons: Anytime Web

    E-Print Network [OSTI]

    Murphy, Robert F.

    Thesis Oral Facts and Reasons: Anytime Web Information Querying to Support Agents and Human using unstructured web information. In addition to processing unstructured information on the Web, our to automatically measure and incorporate the credibility of different web information sources into their claim

  8. Session: Geothermal Research Volcanology Oral presentation

    E-Print Network [OSTI]

    Boyer, Edmond

    and magnetotelluric data acquired during the last 30 years. Oldest electric and magnetotelluric data were digitalizedSession: Geothermal Research ­ Volcanology Oral presentation Contribution of multi-methods geophysics to improve the regional knowledge of Bouillante geothermal Province (Guadeloupe) Lydie Gailler1

  9. EMP Attachment 3 DOE-SC PNNL Site Dose Assessment Guidance

    SciTech Connect (OSTI)

    Snyder, Sandra F.

    2011-12-21

    This Dose Assessment Guidance (DAG) describes methods to use to determine the Maximally-Exposed Individual (MEI) location and to estimate dose impact to that individual under the U.S. Department of Energy Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Site Environmental Monitoring Plan (EMP). This guidance applies to public dose from radioactive material releases to the air from PNNL Site operations. This document is an attachment to the Pacific Northwest National Laboratory (PNNL) Environmental Monitoring Plan (EMP) and describes dose assessment guidance for radiological air emissions. The impact of radiological air emissions from the U.S. Department of Energy Office of Science (DOE-SC) PNNL Site is indicated by dose estimates to a maximally exposed member of the public, referred to as the maximally exposed individual (MEI). Reporting requirements associated with dose to members of the public from radiological air emissions are in 40 CFR Part 61.94, WAC 246-247-080, and DOE Order 458.1. The DOE Order and state standards for dose from radioactive air emissions are consistent with U.S. Environmental Protection Agency (EPA) dose standards in 40 CFR 61.92 (i.e., 10 mrem/yr to a MEI). Despite the fact that the current Contract Requirements Document (CRD) for the DOE-SC PNNL Site operations does not include the requirement to meet DOE CRD 458.1, paragraph 2.b, public dose limits, the DOE dose limits would be met when EPA limits are met.

  10. Title: Information theory Reference: 13791

    E-Print Network [OSTI]

    Overill, Richard E.

    environment or communicates with others. One of the fundamental tenets of information theory a spate of publications appeared applying information theory to many aspects of music analysisTitle: Information theory Reference: 13791 Sort key: informationtheory Version: 3.0 Revision

  11. / R Reference May 25, 2010

    E-Print Network [OSTI]

    Loon, E. Emiel van

    of time searching for a simple way to do what I wanted, but at the end of the semester, I was pleasantly that the entire resulting derived work is distributed under the terms of a permission notice identical to this one, Matlab / R Reference 2 Contents 1 Help 3 2 Entering/building/indexing matrices 3 2.1 Cell arrays

  12. Reference Workbook: Pollution Prevention Plans

    E-Print Network [OSTI]

    #12;Reference Workbook: Pollution Prevention Plans DOE FRAP 1994-35 Prepared for: I Environment Canada Environmental Protection Fraser Pollution Abatement Office 224 West Esplanade North Vancouver, B Pollution Abatement Office. Environment Canada is not responsible for the content of this report but has

  13. References: Elmasri/Navathe:Fundamentals

    E-Print Network [OSTI]

    Brass, Stefan

    7. SQL I 7­1 Part 7: SQL I References: . Elmasri/Navathe:Fundamentals of Database Systems, 3rd Edition, 1999. Chap. 8, ``SQL --- The Relational Database Standard'' (Sect. 8.2, 8.3.3, part of 8. . Date/Darwen: A Guide to the SQL Standard, Fourth Edition, Addison­Wesley , 1997. . Date: A Guide

  14. EMERGENCY PROCEDURES QUICK REFERENCE GUIDE

    E-Print Network [OSTI]

    Frantz, Kyle J.

    1 EMERGENCY PROCEDURES QUICK REFERENCE GUIDE GSU EMERGENCY MANAGEMENT 404-413-0783 GSU POLICE: 404-413-3333 ATLANTA FIRE RESUCE: 911 #12;2 Emergency Response - Order of Priority In any emergency situation, Georgia infrastructure and facilities 3. Resume our research and educational programs Emergency Action Levels: A. Level 1

  15. Radiation Dose From Medical Imaging: A Primer for Emergency Physicians

    E-Print Network [OSTI]

    Jones, Jesse G.A.; Mills, Christopher N.; Mogensen, Monique A.; Lee, Christoph I.

    2012-01-01

    risk imparted by low-dose radiation prove to be correct, CTattributable to low doses of ionizing radiation: assessingreducing radiation dose have developed low-dose CT protocols

  16. Ethnobiological Inferences from Great Basin Oral Tradition

    E-Print Network [OSTI]

    Sutton, Mark Q.

    1989-01-01

    1986 Chia and the Chumash: A Reconsidera- tion of Sage Seedsspp. ) Chia is a term sometimes used to refer to the seeds

  17. Microgrid cyber security reference architecture.

    SciTech Connect (OSTI)

    Veitch, Cynthia K.; Henry, Jordan M.; Richardson, Bryan T.; Hart, Derek H.

    2013-07-01

    This document describes a microgrid cyber security reference architecture. First, we present a high-level concept of operations for a microgrid, including operational modes, necessary power actors, and the communication protocols typically employed. We then describe our motivation for designing a secure microgrid; in particular, we provide general network and industrial control system (ICS)-speci c vulnerabilities, a threat model, information assurance compliance concerns, and design criteria for a microgrid control system network. Our design approach addresses these concerns by segmenting the microgrid control system network into enclaves, grouping enclaves into functional domains, and describing actor communication using data exchange attributes. We describe cyber actors that can help mitigate potential vulnerabilities, in addition to performance bene ts and vulnerability mitigation that may be realized using this reference architecture. To illustrate our design approach, we present a notional a microgrid control system network implementation, including types of communica- tion occurring on that network, example data exchange attributes for actors in the network, an example of how the network can be segmented to create enclaves and functional domains, and how cyber actors can be used to enforce network segmentation and provide the neces- sary level of security. Finally, we describe areas of focus for the further development of the reference architecture.

  18. Emergency Responder Radioactive Material Quick Reference Sheet

    Broader source: Energy.gov [DOE]

    Transportation Emergency Preparedness Program (TEPP) Emergency Responder Radioactive Material Quick Reference Sheet

  19. Generic Argillite/Shale Disposal Reference Case

    E-Print Network [OSTI]

    Zheng, Liange

    2014-01-01

    Shale Disposal Reference Case August 2014 Borehole activity: Oil and gas drilling targets for hydrocarbon resource

  20. Reference Inflow Characterization for River Resource Reference Model (RM2)

    SciTech Connect (OSTI)

    Neary, Vincent S [ORNL

    2011-12-01

    Sandia National Laboratory (SNL) is leading an effort to develop reference models for marine and hydrokinetic technologies and wave and current energy resources. This effort will allow the refinement of technology design tools, accurate estimates of a baseline levelized cost of energy (LCoE), and the identification of the main cost drivers that need to be addressed to achieve a competitive LCoE. As part of this effort, Oak Ridge National Laboratory was charged with examining and reporting reference river inflow characteristics for reference model 2 (RM2). Published turbulent flow data from large rivers, a water supply canal and laboratory flumes, are reviewed to determine the range of velocities, turbulence intensities and turbulent stresses acting on hydrokinetic technologies, and also to evaluate the validity of classical models that describe the depth variation of the time-mean velocity and turbulent normal Reynolds stresses. The classical models are found to generally perform well in describing river inflow characteristics. A potential challenge in river inflow characterization, however, is the high variability of depth and flow over the design life of a hydrokinetic device. This variation can have significant effects on the inflow mean velocity and turbulence intensity experienced by stationary and bottom mounted hydrokinetic energy conversion devices, which requires further investigation, but are expected to have minimal effects on surface mounted devices like the vertical axis turbine device designed for RM2. A simple methodology for obtaining an approximate inflow characterization for surface deployed devices is developed using the relation umax=(7/6)V where V is the bulk velocity and umax is assumed to be the near-surface velocity. The application of this expression is recommended for deriving the local inflow velocity acting on the energy extraction planes of the RM2 vertical axis rotors, where V=Q/A can be calculated given a USGS gage flow time-series and stage vs. cross-section area rating relationship.

  1. We can do better than effective dose for estimating or comparing low-dose radiation risks

    E-Print Network [OSTI]

    Brenner, David Jonathan

    We can do better than effective dose for estimating or comparing low-dose radiation risks D to the radiobiological `detriment' from a particular low-dose radiation exposure ­ detriment representing a balance. Keywords: Low dose risk estimation; Effective dose; Flawed definition; Effective risk 1. INTRODUCTION

  2. EXTRAPOLATING RADIATION-INDUCED CANCER RISKS FROM LOW DOSES TO VERY LOW DOSES

    E-Print Network [OSTI]

    Brenner, David Jonathan

    Paper EXTRAPOLATING RADIATION-INDUCED CANCER RISKS FROM LOW DOSES TO VERY LOW DOSES David J are increased at low doses ( 10 mGy). Discussed here are the issues related to extrapolating radiation risks from low radiation doses to very low doses (

  3. Reference electrode for electrolytic cell

    DOE Patents [OSTI]

    Kessie, R.W.

    1988-07-28

    A reference electrode device is provided for a high temperature electrolytic cell used to electrolytically recover uranium from spent reactor fuel dissolved in an anode pool, the device having a glass tube to enclose the electrode and electrolyte and serve as a conductive membrane with the cell electrolyte, and an outer metal tube about the glass tube to serve as a shield and basket for any glass sections broken by handling of the tube to prevent their contact with the anode pool, the metal tube having perforations to provide access between the bulk of the cell electrolyte and glass membrane. 4 figs.

  4. Electrolytic cell with reference electrode

    DOE Patents [OSTI]

    Kessie, Robert W. (Naperville, IL)

    1989-01-01

    A reference electrode device is provided for a high temperature electrolytic cell used to electrolytically recover uranium from spent reactor fuel dissolved in an anode pool, the device having a glass tube to enclose the electrode and electrolyte and serve as a conductive membrane with the cell electrolyte, and an outer metal tube about the glass tube to serve as a shield and basket for any glass sections broken by handling of the tube to prevent their contact with the anode pool, the metal tube having perforations to provide access between the bulk of the cell electrolyte and glass membrane.

  5. PVWatts Version 1 Technical Reference

    SciTech Connect (OSTI)

    Dobos, A. P.

    2013-10-01

    The NREL PVWatts(TM) calculator is a web application developed by the National Renewable Energy Laboratory (NREL) that estimates the electricity production of a grid-connected photovoltaic system based on a few simple inputs. PVWatts combines a number of sub-models to predict overall system performance, and makes several hidden assumptions about performance parameters. This technical reference details the individual sub-models, documents assumptions and hidden parameters, and explains the sequence of calculations that yield the final system performance estimation.

  6. DOE handbook: Guide to good practices for oral examinations

    SciTech Connect (OSTI)

    1997-09-01

    The purpose of this handbook is to provide DOE nuclear facilities (and others) with guidance that can be used to incorporate oral examination techniques and processes into their training programs. The handbook was developed on the basis of experience in the nuclear industry and incorporates information from civilian, military, commercial, and DOE nuclear sources. Different types of oral examinations are addressed and discussed, including informal, formal, checkouts, facility walkthroughs, operational examinations, and performance demonstrations. Guidelines for administering and grading oral examinations are provided for conducting consistent and reliable oral examinations. 1 tab.

  7. Recommendation 169: Establishment of an Oak Ridge Oral History Program

    Broader source: Energy.gov [DOE]

    The ORSSAB recommends DOE-ORO fully endorse the establishment of an Oak Ridge Oral History Program and provide necessary assistance.

  8. OPI (Oral Proficiency Interview) Information and Registration Packet

    E-Print Network [OSTI]

    Qiu, Weigang

    Education Hunter College requires graduate foreign language education applicants (Italian, French, Spanish, French, Spanish) are required to demonstrate oral proficiency in their language before beginning student

  9. Oral health education for pediatric nurse practitioner students

    E-Print Network [OSTI]

    2013-01-01

    care for children: the pediatric nurse practitioner program.60. Practitioners NAoPN. Pediatric Nurse Practitioner schoolD, Shelley D. Role of pediatric nurse practitioners in oral

  10. Oral communication in the freshman English course 

    E-Print Network [OSTI]

    Kettner, Janet Su Zann

    1974-01-01

    in Teaching th p 'tt . " ~011 ~R't' d C t' ", 8 (0 t. 1957), 183-84. Class discussion is valua'ble not only in handling ideas and matters of form and style, but also as mental discipline for students. A variety of methods exist from simple polling...ORAL COMMUNICATION IN THE FRESHMAN ENGLISH COURSE A Thesis by Janet Su Zann Kettner Submitted to the Graduate College of Texas A 8c M University in partial fulfillment of the requirement, for the degree of MASTER OF ARTS December 1974 Major...

  11. Beta dose distribution for randomly packed microspheres 

    E-Print Network [OSTI]

    Urashkin, Alexander

    2007-04-25

    of radiation dose distribution when utilizing this technique. This study focuses on random packing of microspheres and seeks to determine dose distributions for specific cases. The Monte Carlo Neutral Particle code (MCNP) developed by Los Alamos National...

  12. SNAP operating system reference manual

    SciTech Connect (OSTI)

    Sabuda, J.D.; Polito, J.; Walker, J.L.; Grant, F.H. III

    1982-03-01

    The SNAP Operating System (SOS) is a FORTRAN 77 program which provides assistance to the safeguards analyst who uses the Safeguards Automated Facility Evaluation (SAFE) and the Safeguards Network Analysis Procedure (SNAP) techniques. Features offered by SOS are a data base system for storing a library of SNAP applications, computer graphics representation of SNAP models, a computer graphics editor to develop and modify SNAP models, a SAFE-to-SNAP interface, automatic generation of SNAP input data, and a computer graphic post-processor for SNAP. The SOS Reference Manual provides detailed application information concerning SOS as well as a detailed discussion of all SOS components and their associated command input formats. SOS was developed for the US Nuclear Regulatory Commission's Office of Nuclear Regulatory Research and the US Naval Surface Weapons Center by Pritsker and Associates, Inc., under contract to Sandia National Laboratories.

  13. Investigating packaging effects on bandgap references

    E-Print Network [OSTI]

    Palakodety, Ravi (Ravi Kiran)

    2007-01-01

    This thesis investigates packaging effects on precision bandgap voltage references used in LTC switching regulators. Packaging stress causes a mean offset and room temperature distribution widening of the bandgap reference ...

  14. National Environmental Information Infrastructure Reference Architecture

    E-Print Network [OSTI]

    Greenslade, Diana

    National Environmental Information Infrastructure Reference Architecture Consultation Draft Contributing to the Australian Government National Plan for Environmental Information initiative #12;National Environmental Information Infrastructure Reference Architecture: Consultation Draft Environmental Information

  15. Sandia Energy - Reference Model Project (RMP)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Project (RMP) Home Stationary Power Energy Conversion Efficiency Water Power Reference Model Project (RMP) Reference Model Project (RMP)Tara Camacho-Lopez2015-05-11T21:01:36+00:00...

  16. Charting Future Directions for Reference Service

    E-Print Network [OSTI]

    Stratton, John M.; Devlin, Frances A.

    2011-10-18

    reference desks. Reference questions were coded using a taxonomy based on subject headings used to organize databases into broad categories, in addition to corresponding to professional schools within the University. Using our earlier study as a point...

  17. Hanford Environmental Dose Reconstruction Project. Monthly report

    SciTech Connect (OSTI)

    Cannon, S.D.; Finch, S.M.

    1992-10-01

    The objective of the Hanford Environmental Dose Reconstruction (HEDR) Project is to estimate the radiation doses that individuals and populations could have received from nuclear operations at Hanford since 1944. The independent Technical Steering Panel (TSP) provides technical direction. The project is divided into the following technical tasks. These tasks correspond to the path radionuclides followed from release to impact on humans (dose estimates):Source Terms, Environmental Transport, Environmental Monitoring Data, Demography, Food Consumption, and Agriculture, and Environmental Pathways and Dose Estimates.

  18. Hanford Environmental Dose Reconstruction Project Monthly Report

    SciTech Connect (OSTI)

    Finch, S.M.; McMakin, A.H. (comps.)

    1992-03-01

    The objective of the Hanford Environmental Dose Reconstruction Project is to estimate the radiation doses that individuals and populations could have received from nuclear operations at Hanford since 1944. The project is divided into the following technical tasks. These tasks correspond to the path radionuclides followed, from release to impact on humans (dose estimates): Source Terms, Environmental Transport, Environmental Monitoring Data, Demography, Food Consumption, and Agriculture, and Environmental Pathways and Dose Estimates.

  19. Hanford Environmental Dose Reconstruction Project. Monthly report

    SciTech Connect (OSTI)

    Finch, S.M.; McMakin, A.H. [comps.

    1992-04-01

    The objective of the Hanford Environmental Dose Reconstruction Project is to estimate the radiation doses that individuals and populations could have received from nuclear operations at Hanford since 1944. The project is divided into the following technical tasks. These tasks correspond to the path radionuclides followed, from release to impact on humans (dose estimates): Source terms, environmental transport, environmental monitoring data, demography, food consumption, and agriculture, and environmental pathways and dose estimates.

  20. Intel C++ Compiler User and Reference Guides

    E-Print Network [OSTI]

    Nikolic, Branislav K.

    Intel® C++ Compiler User and Reference Guides Document number: 304968-022US #12;Disclaimer) 2001, Hewlett-Packard Development Company, L.P. #12;#12;v Table of Contents Intel(R) C++ Compiler User and Reference Guides..............................................1 Intel® C++ Compiler User and Reference

  1. Reference Phase of Fresnel Zone Plates

    E-Print Network [OSTI]

    G. W. Webb

    2003-02-28

    The standard zone plate assumes that the shortest ray connecting a radiation source and a detection point has a phase of 0 deg thereby defining a reference phase. Here we examine the experimental consequences of varying this reference phase from 0 deg to 360 deg. It is concluded that reference phase is an intrinsic and useful property of zone plates.

  2. ORISE: Dose modeling and assessments

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformationJesseworkSURVEY UNIVERSE The 2014CapabilitiesCareers CareerDose modeling and

  3. Bibliography of the Scripps Institution of Oceanography Reference Series 2001

    E-Print Network [OSTI]

    Criqui, Nan P.; Kuhns, Kittie K.

    2002-01-01

    Scripps Institution of Oceanography Reference Series 2001.SCRIPPS INSTITUTION OF OCEANOGRAPHY REFERENCE SERIES 01-01

  4. Facilitating Access to Large Digital Oral History Archives through Informedia Technologies

    E-Print Network [OSTI]

    Facilitating Access to Large Digital Oral History Archives through Informedia Technologies Michael understanding technologies to build efficient interfaces into large digital oral history archives video recordings in a large oral history corpus. The specifics of the technologies are overviewed

  5. Discipline Committee (5) Terms of Reference

    E-Print Network [OSTI]

    North, Siobhán

    Angela Fairclough (Adult Dental Care) 2005-10, et seq, 13-14 Mr Michael MacIntosh (Nursing & Midwifery-14 Medicine, Dentistry & Health Mr Mick Ashman (Nursing & Midwifery) 2012-17 Dr Lynne Bingle (Oral Pathology) 2013-18 Dr Tony Blackett (Nursing & Midwifery) 2012-17 Dr Richard Cooper (ScHARR) 2013-18 Dr Bernard

  6. Radiological assessment. A textbook on environmental dose analysis

    SciTech Connect (OSTI)

    Till, J.E.; Meyer, H.R.

    1983-09-01

    Radiological assessment is the quantitative process of estimating the consequences to humans resulting from the release of radionuclides to the biosphere. It is a multidisciplinary subject requiring the expertise of a number of individuals in order to predict source terms, describe environmental transport, calculate internal and external dose, and extrapolate dose to health effects. Up to this time there has been available no comprehensive book describing, on a uniform and comprehensive level, the techniques and models used in radiological assessment. Radiological Assessment is based on material presented at the 1980 Health Physics Society Summer School held in Seattle, Washington. The material has been expanded and edited to make it comprehensive in scope and useful as a text. Topics covered include (1) source terms for nuclear facilities and Medical and Industrial sites; (2) transport of radionuclides in the atmosphere; (3) transport of radionuclides in surface waters; (4) transport of radionuclides in groundwater; (5) terrestrial and aquatic food chain pathways; (6) reference man; a system for internal dose calculations; (7) internal dosimetry; (8) external dosimetry; (9) models for special-case radionuclides; (10) calculation of health effects in irradiated populations; (11) evaluation of uncertainties in environmental radiological assessment models; (12) regulatory standards for environmental releases of radionuclides; (13) development of computer codes for radiological assessment; and (14) assessment of accidental releases of radionuclides.

  7. REPORT OF PH.D. ORAL EXAMINATION COMMITTEE Graduate Group Committee in Bioengineering

    E-Print Network [OSTI]

    Fang-Yen, Christopher

    REPORT OF PH.D. ORAL EXAMINATION COMMITTEE Graduate Group Committee in Bioengineering TO: Dr. Jason Burdick, Chair, Bioengineering Graduate Group FROM: , Chair, Oral Examination Committee for

  8. Multicriteria optimization of the spatial dose distribution

    SciTech Connect (OSTI)

    Schlaefer, Alexander; Viulet, Tiberiu; Muacevic, Alexander; Fürweger, Christoph

    2013-12-15

    Purpose: Treatment planning for radiation therapy involves trade-offs with respect to different clinical goals. Typically, the dose distribution is evaluated based on few statistics and dose–volume histograms. Particularly for stereotactic treatments, the spatial dose distribution represents further criteria, e.g., when considering the gradient between subregions of volumes of interest. The authors have studied how to consider the spatial dose distribution using a multicriteria optimization approach.Methods: The authors have extended a stepwise multicriteria optimization approach to include criteria with respect to the local dose distribution. Based on a three-dimensional visualization of the dose the authors use a software tool allowing interaction with the dose distribution to map objectives with respect to its shape to a constrained optimization problem. Similarly, conflicting criteria are highlighted and the planner decides if and where to relax the shape of the dose distribution.Results: To demonstrate the potential of spatial multicriteria optimization, the tool was applied to a prostate and meningioma case. For the prostate case, local sparing of the rectal wall and shaping of a boost volume are achieved through local relaxations and while maintaining the remaining dose distribution. For the meningioma, target coverage is improved by compromising low dose conformality toward noncritical structures. A comparison of dose–volume histograms illustrates the importance of spatial information for achieving the trade-offs.Conclusions: The results show that it is possible to consider the location of conflicting criteria during treatment planning. Particularly, it is possible to conserve already achieved goals with respect to the dose distribution, to visualize potential trade-offs, and to relax constraints locally. Hence, the proposed approach facilitates a systematic exploration of the optimal shape of the dose distribution.

  9. Internship Checklist Ready Reference C-3

    E-Print Network [OSTI]

    Internship Checklist Ready Reference C-3 College of Engineering, Architecture & Technology Career Services Oklahoma State University College of Engineering, Architecture & Technology Career Services Office

  10. Cover Letter Formula Ready Reference F-3

    E-Print Network [OSTI]

    Cover Letter Formula Ready Reference F-3 College of Engineering, Architecture & Technology Career Services Oklahoma State University College of Engineering, Architecture & Technology Career Services Office

  11. Letter of Refusal Ready Reference F-8

    E-Print Network [OSTI]

    Letter of Refusal Ready Reference F-8 College of Engineering, Architecture & Technology Career Services Oklahoma State University College of College of Engineering, Architecture & Technology Career

  12. Sample Withdrawal Letter Ready Reference F-11

    E-Print Network [OSTI]

    Sample Withdrawal Letter Ready Reference F-11 College of Engineering, Architecture & Technology Career Services Oklahoma State University College of College of Engineering, Architecture & Technology

  13. Sample Application Letter Ready Reference F-5

    E-Print Network [OSTI]

    Sample Application Letter Ready Reference F-5 College of Engineering, Architecture & Technology Career Services Oklahoma State University College of College of Engineering, Architecture & Technology

  14. Sample Networking Letter Ready Reference F-6

    E-Print Network [OSTI]

    Sample Networking Letter Ready Reference F-6 College of Engineering, Architecture & Technology Career Services Oklahoma State University College of College of Engineering, Architecture & Technology

  15. Sample Acceptance Letter Ready Reference F-10

    E-Print Network [OSTI]

    Sample Acceptance Letter Ready Reference F-10 College of Engineering, Architecture & Technology Career Services Oklahoma State University College of College of Engineering, Architecture & Technology

  16. Job Search Steps Ready Reference D-1

    E-Print Network [OSTI]

    Job Search Steps Ready Reference D-1 College of Engineering, Architecture & Technology Career Services Oklahoma State University College of Engineering, Architecture & Technology Career Services Office

  17. Preparing A Vita Ready Reference E-13

    E-Print Network [OSTI]

    Preparing A Vita Ready Reference E-13 College of Engineering, Architecture & Technology Career Services Oklahoma State University College of Engineering, Architecture & Technology Career Services Office

  18. FAQS Reference Guide – Facility Maintenance Management

    Office of Energy Efficiency and Renewable Energy (EERE)

    This reference guide addresses the competency statements in the April 2014 edition of DOE Standard DOE-STD-1181-2014, Facility Maintenance Management Functional Area Qualification Standard.

  19. FAQS Reference Guide – NNSA Package Certification Engineer

    Broader source: Energy.gov [DOE]

    This reference guide addresses the competency statements in the February 2009 edition of DOE-STD-1026-2009, NNSA Package Certification Engineer Functional Area Qualification Standard.

  20. FAQS Reference Guide – General Technical Base

    Broader source: Energy.gov [DOE]

    This reference guide addresses the competency statements in the December 2007 edition of DOE-STD-1146-2007, General Technical Base Functional Area Qualification Standard.

  1. EERE Program Management Quick Reference Guide

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Office of Energy Efficiency and Renewable Energy (EERE) Program Management Reference Guide. It provides an overall description of the EERE program management structure, defines...

  2. Reference Designs for Hydrogen Fueling Stations Webinar

    Broader source: Energy.gov [DOE]

    Access the recording and download the presentation slides from the Fuel Cell Technologies Office webinar "Reference Designs for Hydrogen Fueling Stations" held on October 13, 2015.

  3. SU-E-T-215: Interactive Dose Shaping: Proof of Concept Study for Six Prostate Patients

    SciTech Connect (OSTI)

    Kamerling, CP [The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, London (United Kingdom); German Cancer Research Center (DKFZ), Heidelberg (Germany); Ziegenhein, P; Oelfke, U [The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, London (United Kingdom); Sterzing, F [German Cancer Research Center (DKFZ), Heidelberg (Germany)

    2014-06-01

    Purpose: To provide a proof of concept study for IMRT treatment planning through interactive dose shaping (IDS) by utilising the respective tools to create IMRT treatment plans for six prostate patients. Methods: The IDS planning paradigm aims to perform interactive local dose adaptations of an IMRT plan without compromising already established valuable dose features in real-time. Various IDS tools are available in our in-house treatment planning software Dynaplan and were utilised to create IMRT treatment plans for six patients with an adeno-carcinoma of the prostate. The sequenced IDS treatment plans were compared to conventionally optimised clinically approved plans (9 beams, co-planar). The starting point consisted of open fields. The IDS tools were utilised to sculpt dose out of the rectum and bladder. For each patient, several IDS plans were created, with different trade-offs between organ sparing and target coverage. The reference dose distributions were imported into Dynaplan. For each patient, the IDS treatment plan with a similar or better trade-off between target coverage and OAR sparing was selected for plan evaluation, guided by a physician. Pencil beam dose calculation was performed on a grid with a voxel size of 1.95×1.95×2.0 mm{sup 3}. D98%, D2%, mean dose and dose-volume indicators as specified by Quantec were calculated for plan evaluation. Results: It was possible to utilise the software prototype to generate treatment plans for prostate patient geometries in 15–45 minutes. Individual local dose adaptations could be performed in less than one second. The average differences compared to the reference plans were for the mean dose: 0.0 Gy (boost) and 1.2 Gy (CTV), for D98%: ?1.1 Gy and for D2%: 1.1 Gy (both target volumes). The dose-volume quality indicators were well below the Quantec constraints. Conclusion: Real-time treatment planning utilising IDS is feasible and has the potential to be implemented clinically. Research at The Institute of Cancer Research is supported by Cancer Research UK under Programme C46/A10588.

  4. Spent Nuclear Fuel Project dose management plan

    SciTech Connect (OSTI)

    Bergsman, K.H.

    1996-03-01

    This dose management plan facilitates meeting the dose management and ALARA requirements applicable to the design activities of the Spent Nuclear Fuel Project, and establishes consistency of information used by multiple subprojects in ALARA evaluations. The method for meeting the ALARA requirements applicable to facility designs involves two components. The first is each Spent Nuclear Fuel Project subproject incorporating ALARA principles, ALARA design optimizations, and ALARA design reviews throughout the design of facilities and equipment. The second component is the Spent Nuclear Fuel Project management providing overall dose management guidance to the subprojects and oversight of the subproject dose management efforts.

  5. Development of Reference Models and Design Tools (LCOE Models...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Development of Reference Models and Design Tools (LCOE Models) Development of Reference Models and Design Tools (LCOE Models) Development of Reference Models and Design Tools (LCOE...

  6. Federal Employee Training Desk Reference | Department of Energy

    Energy Savers [EERE]

    College of Learning and Workforce Development Federal Employee Training Desk Reference Federal Employee Training Desk Reference The DOE Federal Employee Training Desk Reference...

  7. Enhancement of cancer stem-like and epithelial?mesenchymal transdifferentiation property in oral epithelial cells with long-term nicotine exposure: Reversal by targeting SNAIL

    SciTech Connect (OSTI)

    Yu, Cheng-Chia; School of Dentistry, Chung Shan Medical University, Taichung, Taiwan; Department of Dentistry, Chung Shan Medical University Hospital, Taichung, Taiwan ; Chang, Yu-Chao; Department of Dentistry, Chung Shan Medical University Hospital, Taichung, Taiwan

    2013-02-01

    Cigarette smoking is one of the major risk factors in the development and further progression of tumorigenesis, including oral squamous cell carcinoma (OSCC). Recent studies suggest that interplay cancer stem-like cells (CSCs) and epithelial?mesenchymal transdifferentiation (EMT) properties are responsible for the tumor maintenance and metastasis in OSCC. The aim of the present study was to investigate the effects of long-term exposure with nicotine, a major component in cigarette, on CSCs and EMT characteristics. The possible reversal regulators were further explored in nicotine-induced CSCs and EMT properties in human oral epithelial (OE) cells. Long-term exposure with nicotine was demonstrated to up-regulate ALDH1 population in normal gingival and primary OSCC OE cells dose-dependently. Moreover, long-term nicotine treatment was found to enhance the self-renewal sphere-forming ability and stemness gene signatures expression and EMT regulators in OE cells. The migration/cell invasiveness/anchorage independent growth and in vivo tumor growth by nude mice xenotransplantation assay was enhanced in long-term nicotine-stimulated OE cells. Knockdown of Snail in long-term nicotine-treated OE cells was found to reduce their CSCs properties. Therapeutic delivery of Si-Snail significantly blocked the xenograft tumorigenesis of long-term nicotine-treated OSCC cells and largely significantly improved the recipient survival. The present study demonstrated that the enrichment of CSCs coupled EMT property in oral epithelial cells induced by nicotine is critical for the development of OSCC tumorigenesis. Targeting Snail might offer a new strategy for the treatment of OSCC patients with smoking habit. -- Highlights: ? Sustained nicotine treatment induced CSCs properties of oral epithelial cells. ? Long-term nicotine treatment enhance EMT properties of oral epithelial cells. ? Long-term nicotine exposure increased tumorigenicity of oral epithelial cells. ? Si-Snail blocked xenograft tumorigenesis of long-term nicotine-treated OSCC cells.

  8. Archived Reference Building Type: Primary school

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the commercial reference building models for existing buildings constructed before 1980, organized by building type and location. A summary ofbuilding types and climate zones is available for reference. Current versions are also available.

  9. Archived Reference Building Type: Primary school

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the commercial reference building models for existing buildings constructed in or after 1980, organized by building type and location. A summary of building types and climate zones is available for reference. Current versions are also available.

  10. OUTLOOK -MOBILE DEVICE ACCESS QUICK REFERENCE GUIDE

    E-Print Network [OSTI]

    Liley, David

    th OUTLOOK - MOBILE DEVICE ACCESS QUICK REFERENCE GUIDE Quick Reference Guide is designed to step you through the initial set up of your Outlook email account on your Mac. Note: If you're opening Microsoft Outlook 2011 for the first time, you will see the Welcome to Microsoft Outlook for Mac window

  11. OUTLOOK -MOBILE DEVICE ACCESS QUICK REFERENCE GUIDE

    E-Print Network [OSTI]

    Liley, David

    th OUTLOOK - MOBILE DEVICE ACCESS QUICK REFERENCE GUIDE This Quick Reference Guide is designed to step you through the setup of your Outlook email account on your mobile device. When to use this Guide is Outlook. NOTE: After you have set up your account you must remove your old GWSync account ITS

  12. Archived Reference Building Type: Secondary school

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the commercial reference building models for existing buildings constructed before 1980, organized by building type and location. A summary ofbuilding types and climate zones is available for reference. Current versions are also available.

  13. Archived Reference Building Type: Secondary school

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the commercial reference building models for existing buildings constructed in or after 1980, organized by building type and location. A summary of building types and climate zones is available for reference. Current versions are also available.

  14. Archived Reference Building Type: Medium office

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the commercial reference building models for existing buildings constructed in or after 1980, organized by building type and location. A summary of building types and climate zones is available for reference. Current versions are also available.

  15. Archived Reference Building Type: Medium office

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the commercial reference building models for existing buildings constructed before 1980, organized by building type and location. A summary ofbuilding types and climate zones is available for reference. Current versions are also available.

  16. Archived Reference Building Type: Outpatient health care

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the commercial reference building models for existing buildings constructed before 1980, organized by building type and location. A summary ofbuilding types and climate zones is available for reference. Current versions are also available.

  17. Archived Reference Building Type: Outpatient health care

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the commercial reference building models for existing buildings constructed in or after 1980, organized by building type and location. A summary of building types and climate zones is available for reference. Current versions are also available.

  18. Intel Fortran Compiler User and Reference Guides

    E-Print Network [OSTI]

    Nikolic, Branislav K.

    Intel® Fortran Compiler User and Reference Guides Document number: 304970-005US #12;Disclaimer) 2001, Hewlett-Packard Development Company, L.P. #12;#12;v Table of Contents Intel(R) Fortran Compiler User and Reference Guides.........................................1 Intel® Fortran Compiler User

  19. Course Number: LIS 7770 and HIS 7860 Title: Oral History: A Methodology for Research

    E-Print Network [OSTI]

    Berdichevsky, Victor

    in a liobrary or archival institution. 10. To understand the technology associated with oral history. Content: 1 of oral history technology. 6. Legal and ethical considerations of oral history. 7. TranscribingCourse Number: LIS 7770 and HIS 7860 Title: Oral History: A Methodology for Research Credits: 3

  20. The Critical World of Harry Berger, Jr.: An Oral History

    E-Print Network [OSTI]

    Vanderscoff, Cameron; Reti, Irene; Berger, Harry Jr.

    2015-01-01

    where I think it does work, this history of interpretation.An Oral History some way, what do you think that does aboutthrough history. And the question is, at what point does it

  1. ORAL TESTIMONY OF JOHN T. WOESTE, Ph.D.

    E-Print Network [OSTI]

    1 ORAL TESTIMONY OF JOHN T. WOESTE, Ph.D. VICE CHAIR, NATIONAL SEA GRANT REVIEW PANEL OFFICE all of these recommendations have been implemented. The Congressionally-directed National Research

  2. BCOM 3223.583 (Oral Communication) Spring 2015

    E-Print Network [OSTI]

    BCOM 3223.583 (Oral Communication) Spring 2015 Instructor: Kim McCrackin Contact Information (presentation visuals) Technological Competence, Written Communication Students should demonstrate effective, incorporate, and document sources Critical Thinking, Written Communication, & Ethical Decision Making Students

  3. An updated dose assessment for Rongelap Island

    SciTech Connect (OSTI)

    Robison, W.L.; Conrado, C.L.; Bogen, K.T.

    1994-07-01

    We have updated the radiological dose assessment for Rongelap Island at Rongelap Atoll using data generated from field trips to the atoll during 1986 through 1993. The data base used for this dose assessment is ten fold greater than that available for the 1982 assessment. Details of each data base are presented along with details about the methods used to calculate the dose from each exposure pathway. The doses are calculated for a resettlement date of January 1, 1995. The maximum annual effective dose is 0.26 mSv y{sup {minus}1} (26 mrem y{sup {minus}1}). The estimated 30-, 50-, and 70-y integral effective doses are 0.0059 Sv (0.59 rem), 0.0082 Sv (0.82 rem), and 0.0097 Sv (0.97 rem), respectively. More than 95% of these estimated doses are due to 137-Cesium ({sup 137}Cs). About 1.5% of the estimated dose is contributed by 90-Strontium ({sup 90}Sr), and about the same amount each by 239+240-Plutonium ({sup 239+240}PU), and 241-Americium ({sup 241}Am).

  4. Oral History, Civil Rights and the Archival Role 

    E-Print Network [OSTI]

    Hankins, Rebecca

    2004-07-19

    , genealogical, and cultural legacies of their communities. These cultures have elevated those individuals who are the oral memories, the griots/griottes that ensure that their legacies endure by chronicling and remembering every minor and major event within... stories by historians and writers who have written extensively on the lives of these two men. Brent Staples of the New York Times puts it succinctly: ?The big lesson for historians in the Hemings-Jefferson case was that the oral histories passed down...

  5. Absorbed dose in target cell nuclei and dose conversion coefficient of radon progeny

    E-Print Network [OSTI]

    Yu, Peter K.N.

    Absorbed dose in target cell nuclei and dose conversion coefficient of radon progeny in the human Abstract To calculate the absorbed dose in the human lung due to inhaled radon progeny, ICRP focussed and secretory cells). The absorbed energy for alpha particles emitted by radon progeny in the human respiratory

  6. SU-E-T-27: A Tool for Routine Quality Assurance of Radiotherapy Dose Calculation Software

    SciTech Connect (OSTI)

    Popple, R; Cardan, R; Duan, J; Wu, X; Shen, S; Brezovich, I

    2014-06-01

    Purpose: Dose calculation software is thoroughly evaluated when it is commissioned; however, evaluation of periodic software updates is typically limited in scope due to staffing constraints and the need to quickly return the treatment planning system to clinical service. We developed a tool for quickly and comprehensively testing and documenting dose calculation software against measured data. Methods: A tool was developed using MatLab (The MathWorks, Natick, MA) for evaluation of dose calculation algorithms against measured data. Inputs to the tool are measured data, reference DICOM RT PLAN files describing the measurements, and dose calculations in DICOM format. The tool consists of a collection of extensible modules that can perform analysis of point dose, depth dose curves, and profiles using dose difference, distance-to-agreement, and the gamma-index. Each module generates a report subsection that is incorporated into a master template, which is converted to final form in portable document format (PDF). Results: After each change to the treatment planning system, a report can be generated in approximately 90 minutes. The tool has been in use for more than 5 years, spanning 5 versions of the eMC and 4 versions of the AAA. We have detected changes to the algorithms that affected clinical practice once during this period. Conclusion: Our tool provides an efficient method for quality assurance of dose calculation software, providing a complete set of tests for an update. Future work includes the addition of plan level tests, allowing incorporation of, for example, the TG-119 test suite for IMRT, and integration with the treatment planning system via an application programming interface. Integration with the planning system will permit fully-automated testing and reporting at scheduled intervals.

  7. Uncertainty analysis for an updated dose assessment for a US nuclear test site: Bikini Atoll

    SciTech Connect (OSTI)

    Bogen, K.T.; Conrado, C.L.; Robison, W.L.

    1995-11-01

    A detailed analysis of uncertainty and interindividual variability in estimated doses was conducted for a rehabilitation scenario for Bikini Island at Bikini Atoll, in which the top 40 cm of soil would be removed in the housing and village area, and the rest of the island is treated with potassium fertilizer, prior to an assumed resettlement date of 1999. Predicted doses were considered for the following fallout-related exposure pathways: ingested Cesium-137 and Strontium-90, external gamma exposure, and inhalation and ingestion of Americium-241 + Plutonium-239+240. Two dietary scenarios were considered: (1) imported foods are available (IA), and (2) imported foods are unavailable (only local foods are consumed) (IUA). Corresponding calculations of uncertainty in estimated population-average dose showed that after {approximately}5 y of residence on Bikini, the upper and lower 95% confidence limits with respect to uncertainty in this dose are estimated to be approximately 2-fold higher and lower than its population-average value, respectively (under both IA and IUA assumptions). Corresponding calculations of interindividual variability in the expected value of dose with respect to uncertainty showed that after {approximately}5 y of residence on Bikini, the upper and lower 95% confidence limits with respect to interindividual variability in this dose are estimated to be approximately 2-fold higher and lower than its expected value, respectively (under both IA and IUA assumptions). For reference, the expected values of population-average dose at age 70 were estimated to be 1.6 and 5.2 cSv under the IA and IUA dietary assumptions, respectively. Assuming that 200 Bikini resettlers would be exposed to local foods (under both IA and IUA assumptions), the maximum 1-y dose received by any Bikini resident is most likely to be approximately 2 and 8 mSv under the IA and IUA assumptions, respectively.

  8. 131I-Tositumomab Myeloablative Radioimmunotherapy for Non-Hodgkin's Lymphoma: Radiation Dose to the Testes

    SciTech Connect (OSTI)

    Hattori, Naoya; Gopal, Ajay K.; Shields, Andrew T.; Fisher, Darrell R.; Gooley, Ted; Pagel, John M.; Press, Oliver W.; Rajendran, Joseph G.

    2012-12-01

    To investigate radiation dose to testes delivered by radiolabeled anti-CD20 antibody and its effects on male sex hormone levels. METHODS: We evaluated dosimetry results for 67 male patients (54 ± 11 years old) with non-Hodgkin lymphoma who underwent myeloablative radioimmunotherapy (RIT) using 131I-tositumomab. In a subset of patients, male sex hormones were measured before and one year after the therapy. RESULTS: Absorbed dose to testes showed greater variability (range = 4.4 to 70.2 Gy) than did dose to lungs (9.5 to 28.4 Gy, p < 0.0001) or liver (6.5 to 27.2 Gy, p < 0.0001). Absorbed dose to the testes per 131I administered (1.18 ± 0.59 mGy/MBq) was not significantly different from that to the liver (1.03 ± 0.29 mGy/MBq, p = 0.08), or to the lungs (1.19 ± 0.50 mGy/MBq, p = 0.889). Pre-therapy levels of total testosterone were below the lower limit of the reference range, and post-therapy evaluation demonstrated further reduction (4.6 ± 1.8 nmol/L (pre-RIT) vs. 3.8 ± 2.9 nmol/L (post-RIT), p < 0.05). Patients receiving higher radiation doses to the testes (? 25 Gy) showed a greater reduction (4.7 ± 1.6 nmol/L (pre RIT) vs. 3.3 ± 2.7 nmol/L (post-RIT), p < 0.05) than did patients receiving lower doses (< 25 Gy), who showed no significant change in total testosterone levels. CONCLUSION: The testicular radiation absorbed dose varied highly among individual patients. Patients receiving higher doses to testes were more likely to show post-RIT suppression of testosterone levels. Key Words: 131I-tositumomab, follicular lymphoma, radioimmunotherapy, radiation dosimetry, male sex hormones. ?

  9. GASPAR II: Technical reference and user guide

    SciTech Connect (OSTI)

    Strenge, D.L.; Bander, T.J.; Soldat, J.K.

    1987-03-01

    This report describes the computer program GASPAR II used by the staff of the US Nuclear Regulatory Commission to perform environmental dose analyses for releases of radioactive effluents from nuclear power plants into the atmosphere. The analyses estimate radiation dose to individuals and population groups from inhalation, ingestion (terrestrial foods), and external-exposure (ground and plume) pathways. The calculated doses provide information for National Environmental Policy Act (NEPA) evaluations and for determining compliance with Appendix I of 10 CFR 50 (the ''ALARA'' philosophy). The report also instructs the user in preparing input to the program, describes the mathematical models that are used, and supplies detailed information on program structure and parameters used to modify the program. 20 refs., 11 figs., 77 tabs.

  10. LIBRARY AND INFORMATION SERVICES DIVISION Current References

    E-Print Network [OSTI]

    LIBRARY AND INFORMATION SERVICES DIVISION Current References (92 -1) ,..... .. , ... ........,., ECOSYSTEMS OF THE FLORIDA KEYS · A Bibliography U. S. DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration National Environmental Satellite, Data, and Information Service National Oceanographic Data Center

  11. Salary Negotiation Ready ReferenceH-3

    E-Print Network [OSTI]

    Salary Negotiation Ready ReferenceH-3 College of Engineering, Architecture & Technology Career" salary on the top end of your range. Although this range may appear high because it is created from

  12. Writing Career Objectives Ready Reference E-5

    E-Print Network [OSTI]

    Writing Career Objectives Ready Reference E-5 College of Engineering, Architecture & Technology in pharmaceutical research" #12;Oklahoma State University College of Engineering, Architecture & Technology Career your practical skills. Examples: -"A position in a large, high tech organization requiring network

  13. Generic Argillite/Shale Disposal Reference Case

    E-Print Network [OSTI]

    Zheng, Liange

    2014-01-01

    S. and K.S. Johnson, (1984). Shale and other argillaceousand R. T. Cygan, (2010). Shale Disposal of U.S. High-LevelDC. Generic Argillite/Shale Disposal Reference Case August

  14. Archive Reference Buildings by Building Type: Warehouse

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the reference buildings for new construction commercial buildings, organized by building type and location. A summary of building types and climate zones is...

  15. New Construction Commercial Reference Buildings — Archive

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the reference buildings for new construction commercial buildings, organized by building type and location. A summary of building types and climate zones is...

  16. Emergency Responder Radioactive Material Quick Reference Sheet

    Broader source: Energy.gov [DOE]

    This job aid is a quick reference to assist emergency responders in identifying preliminary safety precautions that should be taken during the initial response phase after arrival at the scene of...

  17. FAQS Reference Guide – Civil/ Structural Engineering

    Broader source: Energy.gov [DOE]

    This reference guide has been developed to address the competency statements in the March 2004 edition of DOE-STD-1182-2004, Civil/Structural Engineering Functional Area Qualification Standard.

  18. FAQS Reference Guide – Safety Software Quality Assurance

    Broader source: Energy.gov [DOE]

    This reference guide has been developed to address the competency statements in the (March 2011) edition of DOE-STD-1172-2011, Safety Software Quality Assurance Functional Area Qualification Standard.

  19. Pronominal System and Reference in Pulaar

    E-Print Network [OSTI]

    Ba, Ibrahima

    2015-12-20

    This paper examines pronominal reference and the long-distance anaphor in Pulaar, a West African language spoken from Senegal to Niger and Cameroon. I am focusing on Toore, a dialect of Pulaar spoken in southern Senegal. ...

  20. Clause chaining, switch reference and coordination

    E-Print Network [OSTI]

    Nonato, Rafael

    2014-01-01

    In this thesis I ponder over a constellation of phenomena that revolve around switch reference and coordination, drawing mainly on their instantiation in Kisedje (Je, Brazil). I start by investigating Klsedje's case system. ...

  1. Precision Micropower, Low Dropout Voltage References

    E-Print Network [OSTI]

    Berns, Hans-Gerd

    series references are specified over the extended industrial temperature range (-40°C to +85°C) with typical performance specifications over -40°C to +125°C for applications, such as automotive. All

  2. Archive Reference Buildings by Building Type: Supermarket

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the reference buildings for new construction commercial buildings, organized by building type and location. A summary of building types and climate zones is...

  3. Javarifier : inference of reference immutability in Java

    E-Print Network [OSTI]

    Quinonez, Jamie

    2008-01-01

    Javari is an extension of Java that supports reference immutability constraints. Programmers write Javari type qualifiers, such as the readonly type qualifier, in their programs, and the Javari typechecker detects mutation ...

  4. Generating and interpreting referring expressions in context

    E-Print Network [OSTI]

    Smith, Dustin Arthur

    2013-01-01

    Referring expressions with vague and ambiguous modifiers, such as "a quick visit" and "the big meeting," are difficult for computers to interpret because their meanings are defined in part by context. For the hearer to ...

  5. Integrating Referring and Informing in NP Planning 

    E-Print Network [OSTI]

    O'Donnell, Michael; Knott, Alistair; Hitzeman, Janet; Cheng, Hua

    Two of the functions of an NP are to refer (identify a particular entity) and to inform (provide new information about an entity). While many NPs may serve only one of these functions, some NPs conflate the functions, ...

  6. Population Reference Bureau Kenneth W. Wachter

    E-Print Network [OSTI]

    Wachter, Kenneth W.

    -Recapture Estimates 2. Logistic Regression for Stratum Rates 3. Synthetic Estimation for Small Areas KWW ­ p. 14/2 #12,000 households · American Community Survey: Reverse Record Check KWW ­ p. 20/2 #12;References Bell, Robert and M

  7. An expectation model of referring expressions

    E-Print Network [OSTI]

    Kræmer, John, Ph. D. Massachusetts Institute of Technology

    2010-01-01

    This thesis introduces EMRE, an expectation-based model of referring expressions. EMRE is proposed as a model of non-syntactic dependencies - in particular, discourse-level semantic dependencies that bridge sentence gaps. ...

  8. Radiological Dose Calculations for Fusion Facilities

    SciTech Connect (OSTI)

    Michael L. Abbott; Lee C. Cadwallader; David A. Petti

    2003-04-01

    This report summarizes the results and rationale for radiological dose calculations for the maximally exposed individual during fusion accident conditions. Early doses per unit activity (Sieverts per TeraBecquerel) are given for 535 magnetic fusion isotopes of interest for several release scenarios. These data can be used for accident assessment calculations to determine if the accident consequences exceed Nuclear Regulatory Commission and Department of Energy evaluation guides. A generalized yearly dose estimate for routine releases, based on 1 Terabecquerel unit releases per radionuclide, has also been performed using averaged site parameters and assumed populations. These routine release data are useful for assessing designs against US Environmental Protection Agency yearly release limits.

  9. Quantum communication, reference frames and gauge theory

    E-Print Network [OSTI]

    S. J. van Enk

    2006-04-26

    We consider quantum communication in the case that the communicating parties not only do not share a reference frame but use imperfect quantum communication channels, in that each channel applies some fixed but unknown unitary rotation to each qubit. We discuss similarities and differences between reference frames within that quantum communication model and gauge fields in gauge theory. We generalize the concept of refbits and analyze various quantum communication protocols within the communication model.

  10. "Analysis of SOFCs using reference electrodes?

    SciTech Connect (OSTI)

    Finklea, Harry; Chen,Xiaoke; Gerdes,Kirk; Pakalapati, Suryanarayana; Celik, Ismail

    2013-07-01

    Reference electrodes are frequently applied to isolate the performance of one electrode in a solid oxide fuel cell. However, reference electrode simulations raise doubt to veracity of data collected using reference electrodes. The simulations predict that the reported performance for the one electrode will frequently contain performance of both electrodes. Nonetheless, recent reports persistently treat data so collected as ideally isolated. This work confirms the predictions of the reference electrode simulations on two SOFC designs, and to provides a method of validating the data measured in the 3-electrode configuration. Validation is based on the assumption that a change in gas composition to one electrode does not affect the impedance of the other electrode at open circuit voltage. This assumption is supported by a full physics simulation of the SOFC. Three configurations of reference electrode and cell design are experimentally examined using various gas flows and two temperatures. Impedance data are subjected to deconvolution analysis and equivalent circuit fitting and approximate polarization resistances of the cathode and anode are determined. The results demonstrate that the utility of reference electrodes is limited and often wholly inappropriate. Reported impedances and single electrode polarization values must be scrutinized on this basis.

  11. Hanford Environmental Dose Reconstruction Project. Monthly report

    SciTech Connect (OSTI)

    McMakin, A.H.; Cannon, S.D.; Finch, S.M.

    1992-07-01

    The objective of the Hanford Environmental Dose Reconstruction (HEDR) Project is to estimate the radiation doses that individuals and populations could have received from nuclear operations at Hanford since 1944. The TSP consists of experts in environmental pathways, epidemiology, surface-water transport, ground-water transport, statistics, demography, agriculture, meteorology, nuclear engineering, radiation dosimetry, and cultural anthropology. Included are appointed technical members representing the states of Oregon, Washington, and Idaho, a representative of Native American tribes, and an individual representing the public. The project is divided into the following technical tasks. These tasks correspond to the path radionuclides followed from release to impact on humans (dose estimates): Source terms, environmental transport, environmental monitoring data, demography, food consumption, and agriculture, and environmental pathways and dose estimates. Progress is discussed.

  12. Th Cell Gene Expression and Function in Response to Low Dose and Acute Radiation

    SciTech Connect (OSTI)

    Daila S. Gridley, PhD

    2012-03-30

    FINAL TECHNICAL REPORT Supported by the Low Dose Radiation Research Program, Office of Science U.S. Department of Energy Grant No. DE-FG02-07ER64345 Project ID: 0012965 Award Register#: ER64345 Project Manager: Noelle F. Metting, Sc.D. Phone: 301-903-8309 Division SC-23.2 noelle.metting@science.doe.gov Submitted March 2012 To: https://www.osti.gov/elink/241.3.jsp Title: Th Cell Gene Expression and Function in Response to Low Dose and Acute Radiation PI: Daila S. Gridley, Ph.D. Human low dose radiation data have been derived primarily from studies of space and airline flight personnel, nuclear plant workers and others exposed occupationally, as well as victims in the vicinity of atomic bomb explosions. The findings remain inconclusive due to population inconsistencies and complex interactions among total dose, dose rate, radiation quality and age at exposure. Thus, safe limits for low dose occupational irradiation are currently based on data obtained with doses far exceeding the levels expected for the general population and health risks have been largely extrapolated using the linear-nonthreshold dose-response model. The overall working hypothesis of the present study is that priming with low dose, low-linear energy transfer (LET) radiation can ameliorate the response to acute high-dose radiation exposure. We also propose that the efficacy of low-dose induced protection will be dependent upon the form and regimen of the high-dose exposure: photons versus protons versus simulated solar particle event protons (sSPE). The emphasis has been on gene expression and function of CD4+ T helper (Th) lymphocytes harvested from spleens of whole-body irradiated C57BL/6 mice, a strain that provides the genetic background for many genetically engineered strains. Evaluations of the responses of other selected cells, tissues such as skin, and organs such as lung, liver and brain were also initiated (partially funded by other sources). The long-term goal is to provide information that will be useful in estimating human health risks due to radiation that may occur during exposures in the work environment, nuclear/radiological catastrophes, as well as radiotherapy. Several papers have been published, accepted for publication or are in preparation. A number of poster and oral presentations have been made at scientific conferences and workshops. Archived tissues of various types will continue to be evaluated via funding from other sources (the DoE Low Dose Radiation Research Program, Office of Science and this specific grant will be appropriately included in the Acknowledgements of all subsequent publications/presentations). A post-doc and several students have participated in this study. More detailed description of the accomplishments is described in attached file.

  13. Radiation Leukemogenesis at Low Dose Rates

    SciTech Connect (OSTI)

    Weil, Michael; Ullrich, Robert

    2013-09-25

    The major goals of this program were to study the efficacy of low dose rate radiation exposures for the induction of acute myeloid leukemia (AML) and to characterize the leukemias that are caused by radiation exposures at low dose rate. An irradiator facility was designed and constructed that allows large numbers of mice to be irradiated at low dose rates for protracted periods (up to their life span). To the best of our knowledge this facility is unique in the US and it was subsequently used to study radioprotectors being developed for radiological defense (PLoS One. 7(3), e33044, 2012) and is currently being used to study the role of genetic background in susceptibility to radiation-induced lung cancer. One result of the irradiation was expected; low dose rate exposures are ineffective in inducing AML. However, another result was completely unexpected; the irradiated mice had a very high incidence of hepatocellular carcinoma (HCC), approximately 50%. It was unexpected because acute exposures are ineffective in increasing HCC incidence above background. This is a potential important finding for setting exposure limits because it supports the concept of an 'inverse dose rate effect' for some tumor types. That is, for the development of some tumor types low dose rate exposures carry greater risks than acute exposures.

  14. Total ionizing dose effects of domestic SiGe HBTs under different dose rate

    E-Print Network [OSTI]

    Mo-Han, Liu; Wu-Ying, Ma; Xin, Wang; Qi, Guo; Cheng-Fa, He; Ke, Jiang; Xiao-Long, Li; Ming-Zhu, Xiong

    2015-01-01

    The total ionizing radiation (TID) response of commercial NPN silicon germanium hetero-junction bipolar transistors (SiGe HBTs) produced domestic were investigated under the dose rate of 800mGy(Si)/s and 1.3mGy(Si)/s with Co-60 gamma irradiation source, respectively. The changes of the transistor parameter such as Gummel characteristics, excess base current before and after irradiation are investigated. The results of the experiments shows that for the KT1151, the radiation damage have slightly difference under the different dose rate after the prolonged annealing, shows an time dependent effect(TDE). But for the KT9041, the degradations of low dose rate irradiation are more higher than the high dose rate, demonstrate that there have potential enhanced low dose rate sensitive(ELDRS) effect exist on KT9041. The underlying physical mechanisms of the different dose rates response induced by the gamma ray are detailed discussed.

  15. Comparison of radiological dose pathways for tank farm accidents

    SciTech Connect (OSTI)

    Van Keuren, J.C.

    1996-10-30

    This calculation note documents an evaluation of the doses from submersion and ground shine due to a release of tank farm radioactive materials, and a comparison of these doses to the doses from inhalation of the materials. The submersion and ground shine doses are insignificant compared to the inhalation doses. The doses from resuspension are also shown to be negligible for the tank farm analysis conditions.

  16. Radiation Dose Measurement for High-Intensity Laser Interactions...

    Office of Scientific and Technical Information (OSTI)

    Radiation Dose Measurement for High-Intensity Laser Interactions with Solid Targets at SLAC Citation Details In-Document Search Title: Radiation Dose Measurement for High-Intensity...

  17. Importance of Decision Support Implementation in Emergency Department Vancomycin Dosing

    E-Print Network [OSTI]

    Faine, Brett; Mohr, Nicholas; Harland, Kari K.; Rolfes, Kathryn; Porter, Blake; Fuller, Brian M.

    2015-01-01

    The primary outcome was the proportion of vancomycin dosesThe primary outcome was the proportion of vancomycin dosesdose ( Table 2). The proportion of patients receiving a dose

  18. Population estimates for Phase 1: Hanford Environmental Dose Reconstruction Project

    SciTech Connect (OSTI)

    Beck, D.M.; Erickson, A.R.; Harkreader, S.A.

    1992-03-01

    This report summarizes the population estimates of Phase I of the Hanford Environmental Dose Reconstruction (HEDR) Project. These estimates were used to develop preliminary dose estimates.

  19. References - DOE Directives, Delegations, and Requirements

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservation of Fe(II) by Carbon-RichProtonAbout Us HanfordReference MaterialsReference Shelf

  20. Toward Dose Optimization for Fractionated Stereotactic Radiotherapy for Acoustic Neuromas: Comparison of Two Dose Cohorts

    SciTech Connect (OSTI)

    Andrews, David W. Werner-Wasik, Maria; Den, Robert B.; Paek, Sun Ha; Downes-Phillips, Beverly; Willcox, Thomas O.; Bednarz, Greg; Maltenfort, Mitchel; Evans, James J.; Curran, Walter J.

    2009-06-01

    Purpose: To describe our initial experience of fractionated stereotactic radiotherapy dose reduction comparing two dose cohorts with examination of tumor control rates and serviceable hearing preservation rates. Methods and Materials: After institutional review board approval, we initiated a retrospective chart review to study the hearing outcomes and tumor control rates. All data were entered into a JMP, version 7.01, statistical spreadsheet for analysis. Results: A total of 89 patients with serviceable hearing had complete serial audiometric data available for analysis. The higher dose cohort included 43 patients treated to 50.4 Gy with a median follow-up (latest audiogram) of 53 weeks and the lower dose cohort included 46 patients treated to 46.8 Gy with a median follow-up of 65 weeks. The tumor control rate was 100% in both cohorts, and the pure tone average was significantly improved in the low-dose cohort (33 dB vs. 40 dB, p = 0.023, chi-square). When the patient data were analyzed at comparable follow-up points, the actuarial hearing preservation rate was significantly longer for the low-dose cohort than for the high-dose cohort (165 weeks vs. 79 weeks, p = .0318, log-rank). Multivariate analysis revealed the dose cohort (p = 0.0282) and pretreatment Gardner-Robertson class (p = 0.0215) to be highly significant variables affecting the hearing outcome. Conclusion: A lower total dose at 46.8 Gy was associated with a 100% local control tumor rate and a greater hearing preservation rate. An additional dose reduction is justified to achieve the optimal dose that will yield the greatest hearing preservation rate without compromising tumor control for these patients.

  1. Agriculture-related radiation dose calculations

    SciTech Connect (OSTI)

    Furr, J.M.; Mayberry, J.J.; Waite, D.A.

    1987-10-01

    Estimates of radiation dose to the public must be made at each stage in the identification and qualification process leading to siting a high-level nuclear waste repository. Specifically considering the ingestion pathway, this paper examines questions of reliability and adequacy of dose calculations in relation to five stages of data availability (geologic province, region, area, location, and mass balance) and three methods of calculation (population, population/food production, and food production driven). Calculations were done using the model PABLM with data for the Permian and Palo Duro Basins and the Deaf Smith County area. Extra effort expended in gathering agricultural data at succeeding environmental characterization levels does not appear justified, since dose estimates do not differ greatly; that effort would be better spent determining usage of food types that contribute most to the total dose; and that consumption rate and the air dispersion factor are critical to assessment of radiation dose via the ingestion pathway. 17 refs., 9 figs., 32 tabs.

  2. Hanford Environmental Dose Reconstruction Project. Monthly report

    SciTech Connect (OSTI)

    Finch, S. M.; McMakin, A. H.

    1991-09-01

    The objective of the Hanford Environmental Dose Reconstruction Project is to estimate the radiation dose that individuals and populations could have received from nuclear operations at Hanford since 1944. The project is divided into five technical tasks. These tasks correspond to the path radionuclides followed, from release to impact on humans (i.e., dose estimates). The Source Terms Task develops estimates of radioactive emissions from Hanford facilities since 1944. The Environmental Transport Task reconstructs the movements of radioactive particles from the areas of release to populations. The Environmental Monitoring Data Task assemblies, evaluates and reports historical environmental monitoring data. The Demographics, Agriculture and Food Habits Task develops the data needed to identify the populations that could have been affected by the releases. The Environmental Pathways and Dose Estimates Task used the information derived from the other Tasks to estimate the radiation doses individuals could have received from Hanford radiation. This document lists the progress on this project as of September 1991. 3 figs., 2 tabs.

  3. NIST Standard Reference Database 23 NIST Reference Fluid Thermodynamic and Transport Properties--

    E-Print Network [OSTI]

    measurements and models we have taken from the literature, and without which this database would be much#12;NIST Standard Reference Database 23 NIST Reference Fluid Thermodynamic and Transport Properties (NIST) uses its best efforts to deliver a high quality copy of the Database and to verify that the data

  4. Attempted oral vaccination of swine with Brucella neotomae for protection against subsequent challenge with Brucella suis 

    E-Print Network [OSTI]

    Turner, Kenneth Edward

    2001-01-01

    As part of a program to develop an oral vaccine for the control of brucellosis in feral swine, 64 pregnant, domestic swine were orally exposed to Brucella neotomae and subsequently conjunctivally challenged with Brucella suis. In an effort...

  5. Reference reactor module for NASA's lunar surface fission power system

    SciTech Connect (OSTI)

    Poston, David I; Kapernick, Richard J; Dixon, David D; Werner, James; Qualls, Louis; Radel, Ross

    2009-01-01

    Surface fission power systems on the Moon and Mars may provide the first US application of fission reactor technology in space since 1965. The Affordable Fission Surface Power System (AFSPS) study was completed by NASA/DOE to determine the cost of a modest performance, low-technical risk surface power system. The AFSPS concept is now being further developed within the Fission Surface Power (FSP) Project, which is a near-term technology program to demonstrate system-level TRL-6 by 2013. This paper describes the reference FSP reactor module concept, which is designed to provide a net power of 40 kWe for 8 years on the lunar surface; note, the system has been designed with technologies that are fully compatible with a Martian surface application. The reactor concept uses stainless-steel based. UO{sub 2}-fueled, pumped-NaK fission reactor coupled to free-piston Stirling converters. The reactor shielding approach utilizes both in-situ and launched shielding to keep the dose to astronauts much lower than the natural background radiation on the lunar surface. The ultimate goal of this work is to provide a 'workhorse' power system that NASA can utilize in near-term and future Lunar and Martian mission architectures, with the eventual capability to evolve to very high power, low mass systems, for either surface, deep space, and/or orbital missions.

  6. Regularized Equally Sloped Tomography Algorithm for Low Dose X-Ray Computed Tomography

    E-Print Network [OSTI]

    Zhao, Yunzhe

    2012-01-01

    benefits most for the low dose radiation CT protocols, whenet al. “Exposure to low-dose ionizing radiation from medicalobtained from low radiation dose. In theory, radiation dose

  7. Oral Mucositis Prevention By Low-Level Laser Therapy in Head-and-Neck Cancer Patients Undergoing Concurrent Chemoradiotherapy: A Phase III Randomized Study

    SciTech Connect (OSTI)

    Gouvea de Lima, Aline; Villar, Rosangela Correa; Castro, Gilberto de; Antequera, Reynaldo; Gil, Erlon; Rosalmeida, Mauro Cabral; Federico, Miriam Hatsue Honda; Snitcovsky, Igor Moises Longo

    2012-01-01

    Purpose: Oral mucositis is a major complication of concurrent chemoradiotherapy (CRT) in head-and-neck cancer patients. Low-level laser (LLL) therapy is a promising preventive therapy. We aimed to evaluate the efficacy of LLL therapy to decrease severe oral mucositis and its effect on RT interruptions. Methods and Materials: In the present randomized, double-blind, Phase III study, patients received either gallium-aluminum-arsenide LLL therapy 2.5 J/cm{sup 2} or placebo laser, before each radiation fraction. Eligible patients had to have been diagnosed with squamous cell carcinoma or undifferentiated carcinoma of the oral cavity, pharynx, larynx, or metastases to the neck with an unknown primary site. They were treated with adjuvant or definitive CRT, consisting of conventional RT 60-70 Gy (range, 1.8-2.0 Gy/d, 5 times/wk) and concurrent cisplatin. The primary endpoints were the oral mucositis severity in Weeks 2, 4, and 6 and the number of RT interruptions because of mucositis. The secondary endpoints included patient-reported pain scores. To detect a decrease in the incidence of Grade 3 or 4 oral mucositis from 80% to 50%, we planned to enroll 74 patients. Results: A total of 75 patients were included, and 37 patients received preventive LLL therapy. The mean delivered radiation dose was greater in the patients treated with LLL (69.4 vs. 67.9 Gy, p = .03). During CRT, the number of patients diagnosed with Grade 3 or 4 oral mucositis treated with LLL vs. placebo was 4 vs. 5 (Week 2, p = 1.0), 4 vs. 12 (Week 4, p = .08), and 8 vs. 9 (Week 6, p = 1.0), respectively. More of the patients treated with placebo had RT interruptions because of mucositis (6 vs. 0, p = .02). No difference was detected between the treatment arms in the incidence of severe pain. Conclusions: LLL therapy was not effective in reducing severe oral mucositis, although a marginal benefit could not be excluded. It reduced RT interruptions in these head-and-neck cancer patients, which might translate into improved CRT efficacy.

  8. Terms of Reference Information Security Group

    E-Print Network [OSTI]

    Haase, Markus

    Terms of Reference Information Security Group Version 3.1 8 March 2011 © University of Leeds 2011 Security Group Information Security Management 3.1 (8/3/11) Page 2 of 4 Document Control Owner: Kevin Darley, IT Security Co-ordinator, Information Systems Services, University of Leeds Source Location: V

  9. Risk Management Steering Committee Terms of Reference

    E-Print Network [OSTI]

    Victoria, University of

    Risk Management Steering Committee Terms of Reference October 2009 1.0 Purpose The purposes Facilities Management Risk and Insurance Analyst Associate Vice-President Human Resources Administrative of the Steering Committee are: a) to follow a continuous process to understand and communicate risk from

  10. The Behavioral Interview Ready Reference G-7

    E-Print Network [OSTI]

    The Behavioral Interview Ready Reference G-7 College of Engineering, Architecture & Technology Career Services Oklahoma State University College of College of Engineering, Architecture & Technology in technical and high tech industries within the last 10 years. Behavioral interviews are designed to focus

  11. Questioning Yourself Ready Reference B-2

    E-Print Network [OSTI]

    Questioning Yourself Ready Reference B-2 College of Engineering, Architecture & Technology Career Services Oklahoma State University College of Engineering, Architecture & Technology Career Services Office set my own hours? Do I thrive in a high-stress atmosphere, or would I prefer something a bit more

  12. INVESTIGATION Construction of Reference Chromosome-Scale

    E-Print Network [OSTI]

    Douches, David S.

    INVESTIGATION Construction of Reference Chromosome-Scale Pseudomolecules for Potato: Integrating was genotyped with several types of molecular genetic markers to construct a new ~936 cM linkage map comprising and orientation within the pseudo- molecules are closely collinear with independently constructed high density

  13. Quick-Reference Guide to Optimization with

    E-Print Network [OSTI]

    Nikolic, Branislav K.

    Quick-Reference Guide to Optimization with Intel® Compilers version 11 For IA-32 processors, Intel, you may want to check correctness of your application by building it without optimization using /Od (-O0). In this compiler version, all optimization levels assume support for the SSE2 instruction set

  14. Previous Up Next Article From References: 0

    E-Print Network [OSTI]

    Ottino, Julio M.

    (e.g. laminar) fluid flow. Two decades of interdisciplinary studies in this line of investigationPrevious Up Next Article Citations From References: 0 From Reviews: 0 MR2265644 (Review) 37N10 (37D in applications: micro to macro, fluids to solids. Cambridge Monographs on Applied and Computational Mathematics

  15. Xyce parallel electronic simulator : reference guide.

    SciTech Connect (OSTI)

    Mei, Ting; Rankin, Eric Lamont; Thornquist, Heidi K.; Santarelli, Keith R.; Fixel, Deborah A.; Coffey, Todd Stirling; Russo, Thomas V.; Schiek, Richard Louis; Warrender, Christina E.; Keiter, Eric Richard; Pawlowski, Roger Patrick

    2011-05-01

    This document is a reference guide to the Xyce Parallel Electronic Simulator, and is a companion document to the Xyce Users Guide. The focus of this document is (to the extent possible) exhaustively list device parameters, solver options, parser options, and other usage details of Xyce. This document is not intended to be a tutorial. Users who are new to circuit simulation are better served by the Xyce Users Guide. The Xyce Parallel Electronic Simulator has been written to support, in a rigorous manner, the simulation needs of the Sandia National Laboratories electrical designers. It is targeted specifically to run on large-scale parallel computing platforms but also runs well on a variety of architectures including single processor workstations. It also aims to support a variety of devices and models specific to Sandia needs. This document is intended to complement the Xyce Users Guide. It contains comprehensive, detailed information about a number of topics pertinent to the usage of Xyce. Included in this document is a netlist reference for the input-file commands and elements supported within Xyce; a command line reference, which describes the available command line arguments for Xyce; and quick-references for users of other circuit codes, such as Orcad's PSpice and Sandia's ChileSPICE.

  16. Hazard Communication Program 1.0 REFERENCE

    E-Print Network [OSTI]

    de Lijser, Peter

    Hazard Communication Program 1.0 REFERENCE California Code of Regulations, Title 8, Sections 337 the properties and potential safety and health hazards of the materials which they use or to which they are exposed. Employees who use or may be exposed to potentially hazardous substances or harmful physical

  17. Positional reference system for ultraprecision machining

    DOE Patents [OSTI]

    Arnold, J.B.; Burleson, R.R.; Pardue, R.M.

    1980-09-12

    A stable positional reference system for use in improving the cutting tool-to-part contour position in numerical controlled-multiaxis metal turning machines is provided. The reference system employs a plurality of interferometers referenced to orthogonally disposed metering bars which are substantially isolated from machine strain induced position errors for monitoring the part and tool positions relative to the metering bars. A microprocessor-based control system is employed in conjunction with the plurality of positions interferometers and part contour description data input to calculate error components for each axis of movement and output them to corresponding axis driven with appropriate scaling and error compensation. Real-time position control, operating in combination with the reference system, makes possible the positioning of the cutting points of a tool along a part locus with a substantially greater degree of accuracy than has been attained previously in the art by referencing and then monitoring only the tool motion relative to a reference position located on the machine base.

  18. UNIVERSITY PLANNING (SCUP) Terms of Reference

    E-Print Network [OSTI]

    Lennard, William N.

    UNIVERSITY PLANNING (SCUP) Terms of Reference: The Committee is the chief forum within Senate for critical appraisal and coordination of long-term strategic, capital and budget plans for the University planning context, it has specific responsibilities as follows: Long-Range Planning To review and recommend

  19. Campus Planning Committee Terms of Reference

    E-Print Network [OSTI]

    Victoria, University of

    1 Campus Planning Committee Terms of Reference Type: Advisory to President Charge: 1. Recognizing the academic priorities of the institution, the Committee shall advise the President on: a) the long-range plan for the physical development of the Campus; b) amendments to the approved campus plan; c) the University's proposed

  20. Fluid Neutral Momentum Transport Reference Problem

    E-Print Network [OSTI]

    Budny, Robert

    Fluid Neutral Momentum Transport Reference Problem D. P. Stotler, PPPL S. I. Krasheninnikov, UCSD 1 Summary Type of problem: kinetic or fluid neutral transport Physics or algorithm stressed: thermal force term (spatial resolution) in momentum transport equation and treatment of collisions (charge ex- change

  1. Shape Recipes: Scene Representations that Refer

    E-Print Network [OSTI]

    Freeman, William T.

    Shape Recipes: Scene Representations that Refer to the Image William T. Freeman and Antonio to estimate and store. We propose a low-dimensional rep- resentation, called a scene recipe, that relies on the image itself to de- scribe the complex scene configurations. Shape recipes are an example

  2. Office of Classroom Management A quick reference

    E-Print Network [OSTI]

    Thomas, David D.

    Office of Classroom Management A quick reference for how to navigate your classroom's technology of the camera. #12;Office of Classroom Management 1. Press any button other than the "system off" button 2. When and resources www.classroom.umn.edu Classroom Support Hotline: 612-625-1086 ·Controlsforthe

  3. Macrosegregation Macrosegregation refers to variations in composition

    E-Print Network [OSTI]

    Beckermann, Christoph

    in casting processes: (i) Flow that feeds the solidification shrinkage and the contractions of the liquidMacrosegregation Macrosegregation refers to variations in composition that occur in alloy castings variations have a detrimental impact on the subsequent processing behavior and properties of cast materials

  4. LIBRARY AND INFORMATION SERVICES DIVISION Current References

    E-Print Network [OSTI]

    . Satellne. Data. and InformationService National Oceanographic Data Center #12;· GLOBAL CLIMATE CHANGELIBRARY AND INFORMATION SERVICES DIVISION Current References (90 -1) Global Climate Change FEBRUARY of data centers on which an information system must be built. This bibliography offers a selection

  5. R Reference Manual: A gentle overview

    E-Print Network [OSTI]

    Priestley, Jennifer Lewis

    , yet similar to SAS, R is a commands-driven programming environment to execute statistical analysisR Reference Manual: A gentle overview #12;2 Developed and maintained by the Center for Statistics statistical computing packages ­ Excel, SPSS, Minitab, R and SAS. 1 Readers of this manual are assumed to have

  6. Revised Analyses of Decommissioning Reference Non-Fuel-Cycle Facilities

    SciTech Connect (OSTI)

    MC Bierschbach; DR Haffner; KJ Schneider; SM Short

    2002-12-01

    Cost information is developed for the conceptual decommissioning of non-fuel-cycle nuclear facilities that represent a significant decommissioning task in terms of decontamination and disposal activities. This study is a re-evaluation of the original study (NUREG/CR-1754 and NUREG/CR-1754, Addendum 1). The reference facilities examined in this study are the same as in the original study and include: a laboratory for the manufacture of {sup 3}H-labeled compounds; a laboratory for the manufacture of {sup 14}C-labeled compounds; a laboratory for the manufacture of {sup 123}I-labeled compounds; a laboratory for the manufacture of {sup 137}Cs sealed sources; a laboratory for the manufacture of {sup 241}Am sealed sources; and an institutional user laboratory. In addition to the laboratories, three reference sites that require some decommissioning effort were also examined. These sites are: (1) a site with a contaminated drain line and hold-up tank; (2) a site with a contaminated ground surface; and (3) a tailings pile containing uranium and thorium residues. Decommissioning of these reference facilities and sites can be accomplished using techniques and equipment that are in common industrial use. Essentially the same technology assumed in the original study is used in this study. For the reference laboratory-type facilities, the study approach is to first evaluate the decommissioning of individual components (e.g., fume hoods, glove boxes, and building surfaces) that are common to many laboratory facilities. The information obtained from analyzing the individual components of each facility are then used to determine the cost, manpower requirements and dose information for the decommissioning of the entire facility. DECON, the objective of the 1988 Rulemaking for materials facilities, is the decommissioning alternative evaluated for the reference laboratories because it results in the release of the facility for restricted or unrestricted use as soon as possible. For a facility, DECON requires that contaminated components either be: (1) decontaminated to restricted or unrestricted release levels or (2) packaged and shipped to an authorized disposal site. This study considers unrestricted release only. The new decommissioning criteria of July 1997 are too recent for this study to include a cost analysis of the restricted release option, which is now allowed under these new criteria. The costs of decommissioning facility components are generally estimated to be in the range of $140 to $27,000, depending on the type of component, the type and amount of radioactive contamination, the remediation options chosen, and the quantity of radioactive waste generated from decommissioning operations. Estimated costs for decommissioning the example laboratories range from $130,000 to $205,000, assuming aggressive low-level waste (LLW) volume reduction. If only minimal LLW volume reduction is employed, decommissioning costs range from $150,000 to $270,000 for these laboratories. On the basis of estimated decommissioning costs for facility components, the costs of decommissioning typical non-fuel-cycle laboratory facilities are estimated to range from about $25,000 for the decommissioning of a small room containing one or two fume hoods to more than $1 million for the decommissioning of an industrial plant containing several laboratories in which radiochemicals and sealed radioactive sources are prepared. For the reference sites of this study, the basic decommissioning alternatives are: (1) site stabilization followed by long-term care and (2) removal of the waste or contaminated soil to an authorized disposal site. Cost estimates made for decommissioning three reference sites range from about $130,000 for the removal of a contaminated drain line and hold-up tank to more than $23 million for the removal of a tailings pile that contains radioactive residue from ore-processing operations in which tin slag is processed for the recovery of rare metals. Total occupational radiation doses generally range from 0.00007 person-rem to 13 person-rem for

  7. Radiotherapy Dose Fractionation under Parameter Uncertainty

    SciTech Connect (OSTI)

    Davison, Matt; Kim, Daero; Keller, Harald

    2011-11-30

    In radiotherapy, radiation is directed to damage a tumor while avoiding surrounding healthy tissue. Tradeoffs ensue because dose cannot be exactly shaped to the tumor. It is particularly important to ensure that sensitive biological structures near the tumor are not damaged more than a certain amount. Biological tissue is known to have a nonlinear response to incident radiation. The linear quadratic dose response model, which requires the specification of two clinically and experimentally observed response coefficients, is commonly used to model this effect. This model yields an optimization problem giving two different types of optimal dose sequences (fractionation schedules). Which fractionation schedule is preferred depends on the response coefficients. These coefficients are uncertainly known and may differ from patient to patient. Because of this not only the expected outcomes but also the uncertainty around these outcomes are important, and it might not be prudent to select the strategy with the best expected outcome.

  8. DEPARTMENT OF PHYSICS, STANFORD UNIVERSITY FOURTH YEAR ORAL PRESENTATION

    E-Print Network [OSTI]

    Wechsler, Risa H.

    DEPARTMENT OF PHYSICS, STANFORD UNIVERSITY FOURTH YEAR ORAL PRESENTATION REQUIREMENT Fourth year is completed. The form is due to the student services manager by the end of March of the fourth year for fourth year students and on February by the end of the fifth year for student in year five and above who have

  9. Embedded Electrical and Computer Engineering MASTER ORAL DEFENSE

    E-Print Network [OSTI]

    Mahmoodi, Hamid

    Embedded Electrical and Computer Engineering MASTER ORAL DEFENSE TITLE: Low Power Scanner for High of this research is to design a low power integrated system that can be used in vivo for scanning the electrode. A model created in Python provides input vectors and output comparison for the verification process

  10. Embedded Electrical and Computer Engineering MASTER ORAL DEFENSE

    E-Print Network [OSTI]

    Mahmoodi, Hamid

    Embedded Electrical and Computer Engineering MASTER ORAL DEFENSE TITLE: Embedded Systems Design are the devices which involve both hardware and software design in one system simultaneously. There are diverse etc. In order to reflect these trends in education in a hands-on manner, a platform is needed

  11. Assessment of oral premalignancy using elastic scattering spectroscopy

    E-Print Network [OSTI]

    Bigio, Irving J.

    and Maxillofacial Surgery, Eastman Dental Institute, UCL, London, UK b Biomaterial and Tissue Engineering Unit, Eastman Dental Institute, UCL, London, UK c Department of Biomedical Engineering, Department of Electrical.08.008 * Corresponding author. Address: Oral and Maxillofacial Surgery, Eastman Dental Institute, UCL, London, UK. Tel

  12. Bibliography of the Scripps Institution of Oceanography Reference Series 1994

    E-Print Network [OSTI]

    Criqui, Nan P.

    1995-01-01

    OF THE SCRIPPS INSTITUTION OF OCEANOGRAPHY REFERENCE SERIESScripps Institution of Oceanography. July 1994. 179p. 94-17Scripps Institution of Oceanography Reference Series 1994.

  13. Bibliography of the Scripps Institution of Oceanography Reference Series 1997

    E-Print Network [OSTI]

    Jennings, Paige A.

    1998-01-01

    SCRIPPS INSTITUTION OF OCEANOGRAPHY REFERENCE SERIES 97-01Scripps Institution of Oceanography Reference Series 1997.held at Scripps Institution of Oceanography 19 August 1997.

  14. Biomass Scenario Model Documentation: Data and References Lin...

    Office of Scientific and Technical Information (OSTI)

    Documentation: Data and References Lin, Y.; Newes, E.; Bush, B.; Peterson, S.; Stright, D. 09 BIOMASS FUELS BIOMASS SCENARIO MODEL; BSM; BIOMASS; BIOFUEL; MODEL; DATA; REFERENCES;...

  15. Reference Buildings by Climate Zone and Representative City:...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Reference Buildings by Climate Zone and Representative City: 4B Albuquerque, New Mexico Reference Buildings by Climate Zone and Representative City: 4B Albuquerque, New...

  16. Surface Temperature Humidity Reference System Handbook - November 2005

    SciTech Connect (OSTI)

    MT Ritsche

    2005-11-30

    The Surface Temperature and Humidity Reference (SURTHREF) system is intended to provide accurate reference values of ambient temperature and relative humidity for comparison with radiosonde prelaunch values.

  17. A Method for Calculating Reference Evapotranspiration on Daily Time Scales

    E-Print Network [OSTI]

    Farmer, William

    Measures of reference evapotranspiration are essential for applications of agricultural management and water resources engineering. Using numerous esoteric variables, one can calculate daily reference evapotranspiration ...

  18. Reference Buildings by Climate Zone and Representative City:...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    akfairbanksnew2004v1-47-2.zip More Documents & Publications Reference Buildings by Climate Zone and Representative City: 8 Fairbanks, Alaska Reference Buildings by Climate Zone...

  19. Reference Buildings by Climate Zone and Representative City:...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    atxhoustonnew2004v1-47-2.zip More Documents & Publications Reference Buildings by Climate Zone and Representative City: 2A Houston, Texas Reference Buildings by Climate Zone...

  20. Reference Buildings by Climate Zone and Representative City:...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    mdbaltimorenew2004v1-47-2.zip More Documents & Publications Reference Buildings by Climate Zone and Representative City: 4A Baltimore, Maryland Reference Buildings by Climate...

  1. Reference Buildings by Climate Zone and Representative City:...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    agaatlantanew2004v1-47-2.zip More Documents & Publications Reference Buildings by Climate Zone and Representative City: 3A Atlanta, Georgia Reference Buildings by Climate Zone...

  2. Reference Buildings by Climate Zone and Representative City:...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    usaflmiaminew2004v1-47-2.zip More Documents & Publications Reference Buildings by Climate Zone and Representative City: 1A Miami, Florida Reference Buildings by Climate Zone...

  3. Reference Buildings by Climate Zone and Representative City:...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    samthelenanew2004v1-47-2.zip More Documents & Publications Reference Buildings by Climate Zone and Representative City: 6B Helena, Montana Reference Buildings by Climate Zone...

  4. Reference Buildings by Climate Zone and Representative City:...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    acobouldernew2004v1-47-2.zip More Documents & Publications Reference Buildings by Climate Zone and Representative City: 5B Boulder, Colorado Reference Buildings by Climate...

  5. Reference Buildings by Climate Zone and Representative City:...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    awaseattlenew2004v1-47-2.zip More Documents & Publications Reference Buildings by Climate Zone and Representative City: 4C Seattle, Washington Reference Buildings by Climate...

  6. Reference Buildings by Climate Zone and Representative City:...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    nvlasvegasnew2004v1-47-2.zip More Documents & Publications Reference Buildings by Climate Zone and Representative City: 3B Las Vegas, Nevada Reference Buildings by Climate...

  7. Active Contour Models: Application to Oral Lesion Detection in Color Images

    E-Print Network [OSTI]

    Hamarneh, Ghassan

    .g. classification of cancerous vs. non-cancerous lesions). In order to apply the conventional snake formulation of the patient's oral cavity as true-color digital images. Although complementary techniques exist, based e detection (segmentation) of color images of the oral mucosa is thus an important part of computer-aided oral

  8. Dose calculation for electron therapy using an improved LBR method

    SciTech Connect (OSTI)

    Gebreamlak, Wondesen T.; Alkhatib, Hassaan A. [Department of Physics and Astronomy, University of South Carolina, Columbia, South Carolina 29208 (United States); South Carolina Oncology Associates, Columbia, South Carolina 29210 (United States); Tedeschi, David J. [Department of Physics and Astronomy, University of South Carolina, Columbia, South Carolina 29208 (United States)

    2013-07-15

    Purpose: To calculate the percentage depth dose (PDD) of any irregularly shaped electron beam using a modified lateral build-up ratio (LBR) method.Methods: Percentage depth dose curves were measured using 6, 9, 12, and 15 MeV electron beam energies for applicator cone sizes of 6 Multiplication-Sign 6, 10 Multiplication-Sign 10, 14 Multiplication-Sign 14, and 20 Multiplication-Sign 20 cm{sup 2}. Circular cutouts for each cone were prepared from 2.0 cm diameter to the maximum possible size for each cone. In addition, three irregular cutouts were prepared.Results: The LBR for each circular cutout was calculated from the measured PDD curve using the open field of the 14 Multiplication-Sign 14 cm{sup 2} cone as the reference field. Using the LBR values and the radius of the circular cutouts, the corresponding lateral spread parameter [{sigma}{sub R}(z)] of the electron shower was calculated. Unlike the commonly accepted assumption that {sigma}{sub R}(z) is independent of cutout size, it is shown that its value increases linearly with circular cutout size (R). Using this characteristic of the lateral spread parameter, the PDD curves of irregularly shaped cutouts were calculated. Finally, the calculated PDD curves were compared with measured PDD curves.Conclusions: In this research, it is shown that the lateral spread parameter {sigma}{sub R}(z) increases with cutout size. For radii of circular cutout sizes up to the equilibrium range of the electron beam, the increase of {sigma}{sub R}(z) with the cutout size is linear. The percentage difference of the calculated PDD curve from the measured PDD data for irregularly shaped cutouts was under 1.0% in the region between the surface and therapeutic range of the electron beam. Similar results were obtained for four electron beam energies (6, 9, 12, and 15 MeV)

  9. Advanced Computational Approaches for Characterizing Stochastic Cellular Responses to Low Dose, Low Dose Rate Exposures

    SciTech Connect (OSTI)

    Scott, Bobby, R., Ph.D.

    2003-06-27

    OAK - B135 This project final report summarizes modeling research conducted in the U.S. Department of Energy (DOE), Low Dose Radiation Research Program at the Lovelace Respiratory Research Institute from October 1998 through June 2003. The modeling research described involves critically evaluating the validity of the linear nonthreshold (LNT) risk model as it relates to stochastic effects induced in cells by low doses of ionizing radiation and genotoxic chemicals. The LNT model plays a central role in low-dose risk assessment for humans. With the LNT model, any radiation (or genotoxic chemical) exposure is assumed to increase one¡¯s risk of cancer. Based on the LNT model, others have predicted tens of thousands of cancer deaths related to environmental exposure to radioactive material from nuclear accidents (e.g., Chernobyl) and fallout from nuclear weapons testing. Our research has focused on developing biologically based models that explain the shape of dose-response curves for low-dose radiation and genotoxic chemical-induced stochastic effects in cells. Understanding the shape of the dose-response curve for radiation and genotoxic chemical-induced stochastic effects in cells helps to better understand the shape of the dose-response curve for cancer induction in humans. We have used a modeling approach that facilitated model revisions over time, allowing for timely incorporation of new knowledge gained related to the biological basis for low-dose-induced stochastic effects in cells. Both deleterious (e.g., genomic instability, mutations, and neoplastic transformation) and protective (e.g., DNA repair and apoptosis) effects have been included in our modeling. Our most advanced model, NEOTRANS2, involves differing levels of genomic instability. Persistent genomic instability is presumed to be associated with nonspecific, nonlethal mutations and to increase both the risk for neoplastic transformation and for cancer occurrence. Our research results, based on applications of NEOTRANS2, indicate that nonlinear threshold-type, dose-response relationships for excess stochastic effects (problematic nonlethal mutations, neoplastic transformation) should be expected after exposure to low linear energy transfer (LET) gamma rays or gamma rays in combination with high-LET alpha radiation. Similar thresholds are expected for low-dose-rate low-LET beta irradiation. We attribute the thresholds to low-dose, low-LET radiation induced protection against spontaneous mutations and neoplastic transformations. The protection is presumed mainly to involve selective elimination of problematic cells via apoptosis. Low-dose, low-LET radiation is presumed to trigger wide-area cell signaling, which in turn leads to problematic bystander cells (e.g., mutants, neoplastically transformed cells) selectively undergoing apoptosis. Thus, this protective bystander effect leads to selective elimination of problematic cells (a tissue cleansing process in vivo). However, this protective bystander effects is a different process from low-dose stimulation of the immune system. Low-dose, low-LET radiation stimulation of the immune system may explain why thresholds for inducing excess cancer appear much larger (possibly more than 100-fold larger) than thresholds for inducing excess mutations and neoplastic transformations, when the dose rate is low. For ionizing radiation, the current risk assessment paradigm is such that the relative risk (RR) is always ¡Ý 1, no matter how small the dose. Our research results indicate that for low-dose or low-dose-rate, low-LET irradiation, RR < 1 may be more the rule than the exception. Directly tied to the current RR paradigm are the billion-dollar cleanup costs for radionuclide-contaminated DOE sites. Our research results suggest that continued use of the current RR paradigm for which RR ¡Ý 1 could cause more harm than benefit to society (e.g., by spreading unwarranted fear about phantom excess risks associated with low-dose low-LET radiation). Such phantom risks also may arise from risk assessments conducted for com

  10. SU-E-T-44: Angular Dependence of Surface Dose Enhancement Measured On Several Inhomogeneities Using Radiochromic EBT3 Films

    SciTech Connect (OSTI)

    Jansen, A; Schoenfeld, A; Poppinga, D; Chofor, N; Poppe, B [University of Oldenburg, Oldenburg (Germany); Pius Hospital Oldenburg, Oldenburg (Germany)

    2014-06-01

    Purpose: The quantification of the relative surface dose enhancement in dependence on the angle of incidence and the atomic number Z of the surface material. Methods: Experiments were performed with slabs made of aluminum, titanium, copper, silver, dental gold and lead. The metal slabs with equal sizes of 1.0×8.0×8.8mm{sup 3} were embedded in an Octavius 4D phantom (PTW Freiburg, Germany). Radiochromic EBT3 films were used to measure the surface dose for angles of incidence ranging from 0° to 90°. The setup with the metals slabs at the isocenter was irradiated with acceleration voltages of 6MV and 10MV. Water reference measurements were taken under equal conditions. Results: The surface dose enhancement is highest for angles of incidence below 30° and drops significantly for higher. The surface dose enhancement produced by lead and dental gold at 6MV showed a peak of 65%. At 90°, the surface dose enhancement dropped to 15% for both materials. The surface dose enhancements for silver, copper, titanium and aluminum were 45%, 32%, 22% and 12% at 0°, respectively. At an angle of incidence of 80°, the values dropped to 22%, 18%, 12% und 6%. The values for 10MV were very similar. Lead and dental gold showed peaks of 65% und 60%. Their values dropped to 18% at an angle of 90°. The surface dose enhancements for silver, copper, titanium and aluminum were 45%, 30%, 20% and 8% at 0°. At 80° the values dropped to 30%, 20%, 12% and 5%. A dependence of the magnitude of the surface dose enhancement on the atomic number of the surface material can be seen, which is in consistence with literature. Conclusion: The results show that the surface dose enhancements near implant materials with high Z-values should be taken into consideration in radio therapy, even when the angle of incidence is flat.

  11. Human In vivo Dose-Response to Controlled, Low-Dose Low Linear EnergyTransfer Ionizing Radiation Exposure

    E-Print Network [OSTI]

    Rocke, David M.

    Human In vivo Dose-Response to Controlled, Low-Dose Low Linear EnergyTransfer Ionizing Radiation Purpose: The effect of low doses of low ^ linear energy transfer (photon) ionizing radiation (LDIR, and pathway. Conclusions: These results show for the first time that low doses of radiation have an identifi

  12. Reference Design? | OpenEI Community

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onRAPID/Geothermal/Exploration/Colorado <RAPID/Geothermal/WaterEnergyRedfield CampusReedsville,Reference Design? Home

  13. ORISE: Radiological Terms Quick Reference Guide

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformationJesseworkSURVEY UNIVERSEHow ORISE is Making aDose EstimatesRadiochemistryType

  14. Total dose and dose rate models for bipolar transistors in circuit simulation.

    SciTech Connect (OSTI)

    Campbell, Phillip Montgomery; Wix, Steven D.

    2013-05-01

    The objective of this work is to develop a model for total dose effects in bipolar junction transistors for use in circuit simulation. The components of the model are an electrical model of device performance that includes the effects of trapped charge on device behavior, and a model that calculates the trapped charge densities in a specific device structure as a function of radiation dose and dose rate. Simulations based on this model are found to agree well with measurements on a number of devices for which data are available.

  15. Individualized 3D Reconstruction of Normal Tissue Dose for Patients With Long-term Follow-up: A Step Toward Understanding Dose Risk for Late Toxicity

    SciTech Connect (OSTI)

    Ng, Angela; Brock, Kristy K.; Sharpe, Michael B.; Department of Radiation Oncology, University of Toronto, Toronto, Ontario ; Moseley, Joanne L.; Craig, Tim; Department of Radiation Oncology, University of Toronto, Toronto, Ontario ; Hodgson, David C.

    2012-11-15

    Purpose: Understanding the relationship between normal tissue dose and delayed radiation toxicity is an important component of developing more effective radiation therapy. Late outcome data are generally available only for patients who have undergone 2-dimensional (2D) treatment plans. The purpose of this study was to evaluate the accuracy of 3D normal tissue dosimetry derived from reconstructed 2D treatment plans in Hodgkin's lymphoma (HL) patients. Methods and Materials: Three-dimensional lung, heart, and breast volumes were reconstructed from 2D planning radiographs for HL patients who received mediastinal radiation therapy. For each organ, a reference 3D organ was modified with patient-specific structural information, using deformable image processing software. Radiation therapy plans were reconstructed by applying treatment parameters obtained from patient records to the reconstructed 3D volumes. For each reconstructed organ mean dose (D{sub mean}) and volumes covered by at least 5 Gy (V{sub 5}) and 20Gy (V{sub 20}) were calculated. This process was performed for 15 patients who had both 2D and 3D planning data available to compare the reconstructed normal tissue doses with those derived from the primary CT planning data and also for 10 historically treated patients with only 2D imaging available. Results: For patients with 3D planning data, the normal tissue doses could be reconstructed accurately using 2D planning data. Median differences in D{sub mean} between reconstructed and actual plans were 0.18 Gy (lungs), -0.15 Gy (heart), and 0.30 Gy (breasts). Median difference in V{sub 5} and V{sub 20} were less than 2% for each organ. Reconstructed 3D dosimetry was substantially higher in historical mantle-field treatments than contemporary involved-field mediastinal treatments: average D{sub mean} values were 15.2 Gy vs 10.6 Gy (lungs), 27.0 Gy vs 14.3 Gy (heart), and 8.0 Gy vs 3.2 Gy (breasts). Conclusions: Three-dimensional reconstruction of absorbed dose to organs at risk can be estimated accurately many years after exposure by using limited 2D data. Compared to contemporary involved-field treatments, normal tissue doses were significantly higher in historical mantle-field treatments. These methods build capacity to quantify the relationship between 3D normal tissue dose and observed late effects.

  16. A sector-based dosimetric analysis of dose heterogeneity in high-dose-rate prostate brachytherapy

    E-Print Network [OSTI]

    Mesko, S; Park, SJ; Kishan, AU; Demanes, DJ; Kamrava, M

    2015-01-01

    Rogers RL, et al. High dose brachytherapy as monotherapy forcomparison with HDR brachytherapy and preliminary clinicalS. Mesko et al. / Brachytherapy 14 (2015) 173e178 [2] Fukuda

  17. Low Dose Suppression of Neoplastic Transformation in Vitro

    SciTech Connect (OSTI)

    John Leslie Redpath

    2012-05-01

    This grant was to study the low dose suppression of neoplastic transformation in vitro and the shape of the dose-response curve at low doses and dose-rates of ionizing radiation. Previous findings had indicated a suppression of transformation at dose <10cGy of low-LET radiation when delivered at high dose-rate. The present study indicates that such suppression extends out to doses in excess of 100cGy when the dose (from I-125 photons) is delivered at dose-rates as low as 0.2 mGy/min and out to in excess of {approx}25cGy the highest dose studied at the very low dose-rate of 0.5 mGy/day. We also examined dose-rate effects for high energy protons (which are a low-LET radiation) and suppression was evident below {approx}10cGy for high dose-rate delivery and at least out to 50cGy for low dose-rate (20cGy/h) delivery. Finally, we also examined the effect of low doses of 1 GeV/n iron ions (a high-LET radiation) delivered at high dose-rate on transformation at low doses and found a suppression below {approx}10cGy that could be attributable to an adaptive response in bystander cells induced by the associated low-LET delta rays. These results have implications for cancer risk assessment at low doses.

  18. A comparison of neutron dose measurement techniques at the K500 Superconducting Cyclotron facility 

    E-Print Network [OSTI]

    Ford, Michael Scott

    1989-01-01

    to aquiring dose equivalent data. However, in the presence of a 4 Tesla magnetic field, the Lil(Eu) detector produced extremely erroneous results. It became apparent that the output of the detector was dependent upon its position with respect..., previous studies at the Cyclotron Institute indicate that magnetic shielding in the presence of a magnetic field as weak as 4. 5 x10 4 Tesla was ineffective (Schlapper et al. 1984). The BFs-proportional system was calibrated in reference to a known spec...

  19. Efficacy of oral altrenogest for postponing ovulation in the mare 

    E-Print Network [OSTI]

    Murrell, Sandra Lee

    2004-09-30

    Reproductive Systems, Chino, CA). Each insemination dose contained a minimum of 500 million motile sperm cells extended at a 1:1 ratio with E-Z Mixin®-?OF? or E-Z Mixin®-?CST? (Animal...

  20. Evaluation and Control of Radiation Dose to the Embryo/Fetus Guide for Use with Title 10, Code of Federal Regulations, Part 835, Occupational Radiation Protection

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1999-04-29

    This Guide provides an acceptable methodology for establishing and operating a program to control fetal exposure to ionizing radiation and evaluate the resultant dose that will comply with U.S. Department of Energy (DOE) requirements specified in Title 10 of the Code of Federal Regulations (CFR), Part 835, Occupational Radiation Protection (DOE 1998), hereinafter referred to as 10 CFR 835.

  1. Nominal Performance Biosphere Dose Conversion Factor Analysis

    SciTech Connect (OSTI)

    Wasiolek, Maryla A.

    2000-12-21

    The purpose of this report was to document the process leading to development of the Biosphere Dose Conversion Factors (BDCFs) for the postclosure nominal performance of the potential repository at Yucca Mountain. BDCF calculations concerned twenty-four radionuclides. This selection included sixteen radionuclides that may be significant nominal performance dose contributors during the compliance period of up to 10,000 years, five additional radionuclides of importance for up to 1 million years postclosure, and three relatively short-lived radionuclides important for the human intrusion scenario. Consideration of radionuclide buildup in soil caused by previous irrigation with contaminated groundwater was taken into account in the BDCF development. The effect of climate evolution, from the current arid conditions to a wetter and cooler climate, on the BDCF values was evaluated. The analysis included consideration of different exposure pathway's contribution to the BDCFs. Calculations of nominal performance BDCFs used the GENII-S computer code in a series of probabilistic realizations to propagate the uncertainties of input parameters into the output. BDCFs for the nominal performance, when combined with the concentrations of radionuclides in groundwater allow calculation of potential radiation doses to the receptor of interest. Calculated estimates of radionuclide concentration in groundwater result from the saturated zone modeling. The integration of the biosphere modeling results (BDCFs) with the outcomes of the other component models is accomplished in the Total System Performance Assessment (TSPA) to calculate doses to the receptor of interest from radionuclides postulated to be released to the environment from the potential repository at Yucca Mountain.

  2. Department of Energy Construction Safety Reference Guide

    SciTech Connect (OSTI)

    Not Available

    1993-09-01

    DOE has adopted the Occupational Safety and Health Administration (OSHA) regulations Title 29 Code of Federal Regulations (CFR) 1926 ``Safety and Health Regulations for Construction,`` and related parts of 29 CFR 1910, ``Occupational Safety and Health Standards.`` This nonmandatory reference guide is based on these OSHA regulations and, where appropriate, incorporates additional standards, codes, directives, and work practices that are recognized and accepted by DOE and the construction industry. It covers excavation, scaffolding, electricity, fire, signs/barricades, cranes/hoists/conveyors, hand and power tools, concrete/masonry, stairways/ladders, welding/cutting, motor vehicles/mechanical equipment, demolition, materials, blasting, steel erection, etc.

  3. 1993 Solid Waste Reference Forecast Summary

    SciTech Connect (OSTI)

    Valero, O.J.; Blackburn, C.L. [Westinghouse Hanford Co., Richland, WA (United States); Kaae, P.S.; Armacost, L.L.; Garrett, S.M.K. [Pacific Northwest Lab., Richland, WA (United States)

    1993-08-01

    This report, which updates WHC-EP-0567, 1992 Solid Waste Reference Forecast Summary, (WHC 1992) forecasts the volumes of solid wastes to be generated or received at the US Department of Energy Hanford Site during the 30-year period from FY 1993 through FY 2022. The data used in this document were collected from Westinghouse Hanford Company forecasts as well as from surveys of waste generators at other US Department of Energy sites who are now shipping or plan to ship solid wastes to the Hanford Site for disposal. These wastes include low-level and low-level mixed waste, transuranic and transuranic mixed waste, and nonradioactive hazardous waste.

  4. A New Solar Irradiance Reference Spectrum

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach HomeA Better Anode Design to Improve Lithium-Ion Batteries PrintA New Solar Irradiance Reference Spectrum

  5. Technical Reference for Hydrogen Compatibility of Materials

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservationBio-Inspired Solar Fuel ProductionRecoverable15/2008 Technical Reference on

  6. Technical Reference on Hydrogen Compatibility of Materials

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservationBio-Inspired Solar Fuel ProductionRecoverable15/2008 Technical Reference onType

  7. Technical Reference on Hydrogen Compatibility of Materials

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservationBio-Inspired Solar Fuel ProductionRecoverable15/2008 Technical Reference onType1

  8. Administrator References and Logins | Advanced Photon Source

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room News Publications Traditional Knowledge KiosksAboutHelp & Reference Users Home Contacts

  9. Property:Reference material | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTION JEnvironmental Jump to:EA EIS Report Url Jump to:Programmable WavemakingPurchasersReference

  10. Commercial Reference Buildings | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QA J-E-1 SECTIONRobertsdale, Alabama (Utility Company)| Open EnergyColoradoBiomass EnergyCity,Commercial Reference

  11. Dose masking feature for BNCT radiotherapy planning

    DOE Patents [OSTI]

    Cook, Jeremy L. (Greeley, CO); Wessol, Daniel E. (Bozeman, MT); Wheeler, Floyd J. (Idaho Falls, ID)

    2000-01-01

    A system for displaying an accurate model of isodoses to be used in radiotherapy so that appropriate planning can be performed prior to actual treatment on a patient. The nature of the simulation of the radiotherapy planning for BNCT and Fast Neutron Therapy, etc., requires that the doses be computed in the entire volume. The "entire volume" includes the patient and beam geometries as well as the air spaces in between. Isodoses derived from the computed doses will therefore extend into the air regions between the patient and beam geometries and thus depict the unrealistic possibility that radiation deposition occurs in regions containing no physical media. This problem is solved by computing the doses for the entire geometry and then masking the physical and air regions along with the isodose contours superimposed over the patient image at the corresponding plane. The user is thus able to mask out (remove) the contour lines from the unwanted areas of the image by selecting the appropriate contour masking region from the raster image.

  12. Reference worldwide model for antineutrinos from reactors

    E-Print Network [OSTI]

    Marica Baldoncini; Ivan Callegari; Giovanni Fiorentini; Fabio Mantovani; Barbara Ricci; Virginia Strati; Gerti Xhixha

    2015-02-16

    Antineutrinos produced at nuclear reactors constitute a severe source of background for the detection of geoneutrinos, which bring to the Earth's surface information about natural radioactivity in the whole planet. In this framework we provide a reference worldwide model for antineutrinos from reactors, in view of reactors operational records yearly published by the International Atomic Energy Agency (IAEA). We evaluate the expected signal from commercial reactors for ongoing (KamLAND and Borexino), planned (SNO+) and proposed (Juno, RENO-50, LENA and Hanohano) experimental sites. Uncertainties related to reactor antineutrino production, propagation and detection processes are estimated using a Monte Carlo based approach, which provides an overall site dependent uncertainty on the signal in the geoneutrino energy window on the order of 3%. We also implement the off-equilibrium correction to the reference reactor spectra associated with the long-lived isotopes and we estimate a 2.4% increase of the unoscillated event rate in the geoneutrino energy window due to the storage of spent nuclear fuels in the cooling pools. We predict that the research reactors contribute to less than 0.2% to the commercial reactor signal in the investigated 14 sites. We perform a multitemporal analysis of the expected reactor signal over a time lapse of 10 years using reactor operational records collected in a comprehensive database published at www.fe.infn.it/antineutrino.

  13. Generic Argillite/Shale Disposal Reference Case

    SciTech Connect (OSTI)

    Zheng, Liange; Colon, Carlos Jové; Bianchi, Marco; Birkholzer, Jens

    2014-08-08

    Radioactive waste disposal in a deep subsurface repository hosted in clay/shale/argillite is a subject of widespread interest given the desirable isolation properties, geochemically reduced conditions, and widespread geologic occurrence of this rock type (Hansen 2010; Bianchi et al. 2013). Bianchi et al. (2013) provides a description of diffusion in a clay-hosted repository based on single-phase flow and full saturation using parametric data from documented studies in Europe (e.g., ANDRA 2005). The predominance of diffusive transport and sorption phenomena in this clay media are key attributes to impede radionuclide mobility making clay rock formations target sites for disposal of high-level radioactive waste. The reports by Hansen et al. (2010) and those from numerous studies in clay-hosted underground research laboratories (URLs) in Belgium, France and Switzerland outline the extensive scientific knowledge obtained to assess long-term clay/shale/argillite repository isolation performance of nuclear waste. In the past several years under the UFDC, various kinds of models have been developed for argillite repository to demonstrate the model capability, understand the spatial and temporal alteration of the repository, and evaluate different scenarios. These models include the coupled Thermal-Hydrological-Mechanical (THM) and Thermal-Hydrological-Mechanical-Chemical (THMC) models (e.g. Liu et al. 2013; Rutqvist et al. 2014a, Zheng et al. 2014a) that focus on THMC processes in the Engineered Barrier System (EBS) bentonite and argillite host hock, the large scale hydrogeologic model (Bianchi et al. 2014) that investigates the hydraulic connection between an emplacement drift and surrounding hydrogeological units, and Disposal Systems Evaluation Framework (DSEF) models (Greenberg et al. 2013) that evaluate thermal evolution in the host rock approximated as a thermal conduction process to facilitate the analysis of design options. However, the assumptions and the properties (parameters) used in these models are different, which not only make inter-model comparisons difficult, but also compromise the applicability of the lessons learned from one model to another model. The establishment of a reference case would therefore be helpful to set up a baseline for model development. A generic salt repository reference case was developed in Freeze et al. (2013) and the generic argillite repository reference case is presented in this report. The definition of a reference case requires the characterization of the waste inventory, waste form, waste package, repository layout, EBS backfill, host rock, and biosphere. This report mainly documents the processes in EBS bentonite and host rock that are potentially important for performance assessment and properties that are needed to describe these processes, with brief description other components such as waste inventory, waste form, waste package, repository layout, aquifer, and biosphere. A thorough description of the generic argillite repository reference case will be given in Jové Colon et al. (2014).

  14. Direct determination of internal radiation dose in human blood

    E-Print Network [OSTI]

    Tan?r, Ayse Güne?

    2014-01-01

    The purpose of this study is to measure the internal radiation dose using a human blood sample. In the literature, there is no process that allows the direct measurement of the internal radiation dose received by a person. The luminescence counts from a blood sample having a laboratory-injected radiation dose and the waste blood of the patient injected with a radiopharmaceutical for diagnostic purposes were both measured. The decay and dose-response curves were plotted for the different doses. The doses received by the different blood aliquots can be determined by interpolating the luminescence counts to the dose-response curve. This study shows that the dose received by a person can be measured directly, simply and retrospectively by using only a very small amount of blood sample. The results will have important ramifications for the medicine and healthcare fields in particular. This will also be very important in cases of suspicion of radiation poisoning, malpractice and so on.

  15. Realistic simulation of reduced-dose CT with noise modeling and sinogram synthesis using DICOM CT images

    SciTech Connect (OSTI)

    Won Kim, Chang; Kim, Jong Hyo

    2014-01-15

    Purpose: Reducing the patient dose while maintaining the diagnostic image quality during CT exams is the subject of a growing number of studies, in which simulations of reduced-dose CT with patient data have been used as an effective technique when exploring the potential of various dose reduction techniques. Difficulties in accessing raw sinogram data, however, have restricted the use of this technique to a limited number of institutions. Here, we present a novel reduced-dose CT simulation technique which provides realistic low-dose images without the requirement of raw sinogram data. Methods: Two key characteristics of CT systems, the noise equivalent quanta (NEQ) and the algorithmic modulation transfer function (MTF), were measured for various combinations of object attenuation and tube currents by analyzing the noise power spectrum (NPS) of CT images obtained with a set of phantoms. Those measurements were used to develop a comprehensive CT noise model covering the reduced x-ray photon flux, object attenuation, system noise, and bow-tie filter, which was then employed to generate a simulated noise sinogram for the reduced-dose condition with the use of a synthetic sinogram generated from a reference CT image. The simulated noise sinogram was filtered with the algorithmic MTF and back-projected to create a noise CT image, which was then added to the reference CT image, finally providing a simulated reduced-dose CT image. The simulation performance was evaluated in terms of the degree of NPS similarity, the noise magnitude, the bow-tie filter effect, and the streak noise pattern at photon starvation sites with the set of phantom images. Results: The simulation results showed good agreement with actual low-dose CT images in terms of their visual appearance and in a quantitative evaluation test. The magnitude and shape of the NPS curves of the simulated low-dose images agreed well with those of real low-dose images, showing discrepancies of less than +/?3.2% in terms of the noise power at the peak height and +/?1.2% in terms of the spatial frequency at the peak height. The magnitudes of the noise measured for 12 different combinations the phantom size, tube current, and reconstruction kernel for the simulated and real low-dose images were very similar, with differences of 0.1 to 4.7%. Thep value for a statistical testing of the difference in the noise magnitude ranged from 0.99 to 0.11, showing that there was no difference statistically between the noise magnitudes of the real and simulated low-dose images using our method. The strength and pattern of the streak noise in an anthropomorphic phantom was also consistent with expectations. Conclusions: A novel reduced-dose CT simulation technique was developed which uses only CT images while not requiring raw sinogram data. Our method can provide realistic simulation results under reduced-dose conditions both in terms of the noise magnitude and the textual appearance. This technique has the potential to promote clinical research for patient dose reductions.

  16. Toward an organ based dose prescription method for the improved accuracy of murine dose in orthovoltage x-ray irradiators

    SciTech Connect (OSTI)

    Belley, Matthew D.; Wang, Chu [Medical Physics Graduate Program, Duke University Medical Center, Durham, North Carolina 27705 (United States)] [Medical Physics Graduate Program, Duke University Medical Center, Durham, North Carolina 27705 (United States); Nguyen, Giao; Gunasingha, Rathnayaka [Duke Radiation Dosimetry Laboratory, Duke University Medical Center, Durham, North Carolina 27710 (United States)] [Duke Radiation Dosimetry Laboratory, Duke University Medical Center, Durham, North Carolina 27710 (United States); Chao, Nelson J. [Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710 and Department of Immunology, Duke University Medical Center, Durham, North Carolina 27710 (United States)] [Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710 and Department of Immunology, Duke University Medical Center, Durham, North Carolina 27710 (United States); Chen, Benny J. [Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710 (United States)] [Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710 (United States); Dewhirst, Mark W. [Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710 (United States)] [Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710 (United States); Yoshizumi, Terry T., E-mail: terry.yoshizumi@duke.edu [Duke Radiation Dosimetry Laboratory, Duke University Medical Center, Durham, North Carolina 27710 (United States); Department of Radiology, Duke University Medical Center, Durham, North Carolina 27710 (United States); Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710 (United States)

    2014-03-15

    Purpose: Accurate dosimetry is essential when irradiating mice to ensure that functional and molecular endpoints are well understood for the radiation dose delivered. Conventional methods of prescribing dose in mice involve the use of a single dose rate measurement and assume a uniform average dose throughout all organs of the entire mouse. Here, the authors report the individual average organ dose values for the irradiation of a 12, 23, and 33 g mouse on a 320 kVp x-ray irradiator and calculate the resulting error from using conventional dose prescription methods. Methods: Organ doses were simulated in the Geant4 application for tomographic emission toolkit using the MOBY mouse whole-body phantom. Dosimetry was performed for three beams utilizing filters A (1.65 mm Al), B (2.0 mm Al), and C (0.1 mm Cu + 2.5 mm Al), respectively. In addition, simulated x-ray spectra were validated with physical half-value layer measurements. Results: Average doses in soft-tissue organs were found to vary by as much as 23%–32% depending on the filter. Compared to filters A and B, filter C provided the hardest beam and had the lowest variation in soft-tissue average organ doses across all mouse sizes, with a difference of 23% for the median mouse size of 23 g. Conclusions: This work suggests a new dose prescription method in small animal dosimetry: it presents a departure from the conventional approach of assigninga single dose value for irradiation of mice to a more comprehensive approach of characterizing individual organ doses to minimize the error and uncertainty. In human radiation therapy, clinical treatment planning establishes the target dose as well as the dose distribution, however, this has generally not been done in small animal research. These results suggest that organ dose errors will be minimized by calibrating the dose rates for all filters, and using different dose rates for different organs.

  17. Hanford Environmental Dose Reconstruction Project monthly report, May 1992

    SciTech Connect (OSTI)

    Finch, S.M.; McMakin, A.H. [comps.

    1992-08-01

    The objective of the Hanford Environmental Dose Reconstruction Project is to estimate the radiation doses that individuals and populations could have received from nuclear operations at Hanford since 1944. The project is divided into the following technical tasks. These task correspond to the path radionuclides followed, from release to impact on humans (dose estimates): Source terms, environmental transport, environmental monitoring data, demography, food consumption, and agriculture, and environmental pathways and dose estimates.

  18. Hanford Environmental Dose Reconstruction Project monthly report, May 1992

    SciTech Connect (OSTI)

    Finch, S.M.; McMakin, A.H. (comps.)

    1992-01-01

    The objective of the Hanford Environmental Dose Reconstruction Project is to estimate the radiation doses that individuals and populations could have received from nuclear operations at Hanford since 1944. The project is divided into the following technical tasks. These task correspond to the path radionuclides followed, from release to impact on humans (dose estimates): Source terms, environmental transport, environmental monitoring data, demography, food consumption, and agriculture, and environmental pathways and dose estimates.

  19. A Statistical Approach for Achievable Dose Querying in IMRT Planning

    E-Print Network [OSTI]

    Kazhdan, Michael

    Introduction We explore a data-driven approach for achievable dose querying in intensity- modulated radiation specifies too low a target dose to the OAR, the treatment plan may not be realiz- able and the treatmentA Statistical Approach for Achievable Dose Querying in IMRT Planning Patricio Simari1 , Binbin Wu2

  20. Cardiac Computed Tomography Radiation Dose Reduction Using Interior Reconstruction Algorithm

    E-Print Network [OSTI]

    Wang, Ge

    recommendations are to use radiation dose as low as possible while satisfying the diagnosis requirement. ThereforeCardiac Computed Tomography Radiation Dose Reduction Using Interior Reconstruction Algorithm. Jeffrey Carr, MD,§¶ and Ge Wang, PhD,*Þþ Abstract: High x-ray radiation dose is a major public concern

  1. WECC Variable Generation Planning Reference Book

    SciTech Connect (OSTI)

    Makarov, Yuri V.; Du, Pengwei; Etingov, Pavel V.; Ma, Jian; Vyakaranam, Bharat

    2013-05-14

    This planning reference book is a document reflecting a Western Electricity Coordination Council (WECC) effort to put together multiple sources of information and provide a clear, systemic, comprehensive outline of the problems, both existing and anticipated; their impacts on the system; currently used and proposed solutions by the industry and research community; planning practices; new technologies, equipment, and standards; and expected future trends. This living (periodically updated) document could help WECC and other practicing engineers, especially the younger generation of engineers joining the workforce, to get familiar with a large variety of information related to the integration of variable resources into the WECC system, bypassing in part the need for time-consuming information gathering and learning processes from more experienced engineers or from the literature.

  2. ACAA fly ash basics: quick reference card

    SciTech Connect (OSTI)

    2006-07-01

    Fly ash is a fine powdery material created when coal is burned to generate electricity. Before escaping into the environment via the utility stacks, the ash is collected and may be stored for beneficial uses or disposed of, if necessary. The use of fly ash provides environmental benefits, such as the conservation of natural resources, the reduction of greenhouse gas emissions and eliminating the needed for ash disposal in landfills. It is also a valuable mineral resource that is used in construction and manufacturing. Fly ash is used in the production of Portland cement, concrete, mortars and stuccos, manufactured aggregates along with various agricultural applications. As mineral filler, fly ash can be used for paints, shingles, carpet backing, plastics, metal castings and other purposes. This quick reference card is intended to provide the reader basic source, identification and composition, information specifically related to fly ash.

  3. Semantic Features for Classifying Referring Search Terms

    SciTech Connect (OSTI)

    May, Chandler J.; Henry, Michael J.; McGrath, Liam R.; Bell, Eric B.; Marshall, Eric J.; Gregory, Michelle L.

    2012-05-11

    When an internet user clicks on a result in a search engine, a request is submitted to the destination web server that includes a referrer field containing the search terms given by the user. Using this information, website owners can analyze the search terms leading to their websites to better understand their visitors needs. This work explores some of the features that can be used for classification-based analysis of such referring search terms. We present initial results for the example task of classifying HTTP requests countries of origin. A system that can accurately predict the country of origin from query text may be a valuable complement to IP lookup methods which are susceptible to the obfuscation of dereferrers or proxies. We suggest that the addition of semantic features improves classifier performance in this example application. We begin by looking at related work and presenting our approach. After describing initial experiments and results, we discuss paths forward for this work.

  4. Webinar October 13: Reference Designs for Hydrogen Fueling Stations...

    Broader source: Energy.gov (indexed) [DOE]

    titled "Reference Designs for Hydrogen Fueling Stations" on Tuesday, October 13, from 12 to 1 p.m. Eastern Daylight Time (EDT). The goal of the H2FIRST Reference Station Design...

  5. United States Department of the Interior - RM-53 - Reference...

    Open Energy Info (EERE)

    search OpenEI Reference LibraryAdd to library PermittingRegulatory Guidance - GuideHandbook: United States Department of the Interior - RM-53 - Reference Manual - Special Park...

  6. ORNL/TM-2012/501 Small Hydropower Cost Reference

    E-Print Network [OSTI]

    Post, Wilfred M.

    ORNL/TM-2012/501 Small Hydropower Cost Reference Model October 2012 Prepared by Qin Fen (Katherine Government or any agency thereof. #12;ORNL/TM-2012/501 Small Hydropower Cost Reference Model Final Project

  7. Reference Buildings by Climate Zone and Representative City:...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    hicago-oharenew2004v1-47-2.zip More Documents & Publications Reference Buildings by Climate Zone and Representative City: 5A Chicago, Illinois Reference Buildings by Climate...

  8. H2FIRST Reference Station Design Task: Project Deliverable 2...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Reference Station Design Task: Project Deliverable 2-2 H2FIRST Reference Station Design Task: Project Deliverable 2-2 This H2FIRST project report, published in April 2015, presents...

  9. Air Quality: Air Pollutants, SLAC Emissions Sources, and Regulatory Reference

    E-Print Network [OSTI]

    Wechsler, Risa H.

    Air Quality: Air Pollutants, SLAC Emissions Sources, and Regulatory Reference Department: Chemical permit regulations are designed to track, record, and control air pollutants belonging to several on chemical classifications. This reference outlines major categories of air pollutants found at SLAC

  10. Low-Dose Radiotherapy in Indolent Lymphoma

    SciTech Connect (OSTI)

    Rossier, Christine [Department of Radiation Oncology, Centre Hospitalier Universitaire Vaudois, Lausanne (Switzerland); Schick, Ulrike; Miralbell, Raymond [Department of Radiation Oncology, University Hospital of Geneva (Switzerland); Mirimanoff, Rene O. [Department of Radiation Oncology, Centre Hospitalier Universitaire Vaudois, Lausanne (Switzerland); Weber, Damien C. [Department of Radiation Oncology, University Hospital of Geneva (Switzerland); Ozsahin, Mahmut, E-mail: Esat-Mahmut.Ozsahin@chuv.ch [Department of Radiation Oncology, Centre Hospitalier Universitaire Vaudois, Lausanne (Switzerland)

    2011-11-01

    Purpose: To assess the response rate, duration of response, and overall survival after low-dose involved-field radiotherapy in patients with recurrent low-grade lymphoma or chronic lymphocytic leukemia (CLL). Methods and Materials: Forty-three (24 women, 19 men) consecutive patients with indolent lymphoma or CLL were treated with a total dose of 4 Gy (2 x 2 Gy) using 6- 18-MV photons. The median age was 73 years (range, 39-88). Radiotherapy was given either after (n = 32; 75%) or before (n = 11; 25%) chemotherapy. The median time from diagnosis was 48 months (range, 1-249). The median follow-up period was 20 months (range, 1-56). Results: The overall response rate was 90%. Twelve patients (28%) had a complete response, 15 (35%) had a partial response, 11 (26%) had stable disease, and 5 (11%) had progressive disease. The median overall survival for patients with a positive response (complete response/partial response/stable disease) was 41 months; for patients with progressive disease it was 6 months (p = 0.001). The median time to in-field progression was 21 months (range, 0-24), and the median time to out-field progression was 8 months (range, 0-40). The 3-year in-field control was 92% in patients with complete response (median was not reached). The median time to in-field progression was 9 months (range, 0.5-24) in patients with partial response and 6 months (range, 0.6-6) in those with stable disease (p < 0.05). Younger age, positive response to radiotherapy, and no previous chemotherapy were the best factors influencing the outcome. Conclusions: Low-dose involved-field radiotherapy is an effective treatment in the management of patients with recurrent low-grade lymphoma or CLL.

  11. ORISE: Radiation Dose Estimates and Other Compendia

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room NewsInformationJesseworkSURVEY UNIVERSEHow ORISE is Making aDose Estimates and Other Compendia

  12. RECENT REFERENCES: JULY 1, 2006 TO SEPTEMBER 30, 2006

    SciTech Connect (OSTI)

    WINCHELL, D.F.

    2006-09-30

    This document lists experimental references added to Nuclear Science References (NSR) during the period July 1, 2006 to September 30, 2006. The first section lists keynumbers and keywords sorted by mass and nuclide. The second section lists all references, ordered by keynumber.

  13. RECENT REFERENCES: JANUARY 1, 2005 TO DECEMBER 31, 2005

    SciTech Connect (OSTI)

    WINCHELL, D.F.

    2005-12-31

    This document lists experimental references added to Nuclear Science References (NSR) during the period January 1, 2005 to December 31, 2005. The first section lists keynumbers and keywords sorted by mass and nuclide. The second section lists all references, ordered by keynumber.

  14. RECENT REFERENCES: APRIL 1, 2006 TO JUNE 30, 2006

    SciTech Connect (OSTI)

    WINCHELL, D.F.

    2006-06-30

    This document lists experimental references added to Nuclear Science References (NSR) during the period April 1, 2006 to June 30, 2006. The first section lists keynumbers and keywords sorted by mass and nuclide. The second section lists all references, ordered by keynumber.

  15. RECENT REFERENCES: OCTOBER 1, 2005 TO DECEMBER 31, 2005

    SciTech Connect (OSTI)

    WINCHELL, D.F.

    2005-12-31

    This document lists experimental references added to Nuclear Science References (NSR) during the period October 1, 2005 to December 31, 2005. The first section lists keynumbers and keywords sorted by mass and nuclide. The second section lists all references, ordered by keynumber.

  16. On the Intrinsic Locality Properties of Web Reference Streams

    E-Print Network [OSTI]

    Keinan, Alon

    On the Intrinsic Locality Properties of Web Reference Streams Rodrigo Fonseca Virg´ilio Almeida in the study of Web reference streams: sequences of requests for Web objects. In particular, many studies have into the nature of reference stream transformations in the Web. I. INTRODUCTION Considerable effort has gone

  17. SU-E-T-176: Examination of Surface Dose Enhancement Using Radiochromic EBT3-Films in a Cylindrical Setup

    SciTech Connect (OSTI)

    Failing, T; Chofor, N; Poppinga, D; Schoenfeld, A; Poppe, B [Pius Hospital and Carl von Ossietzky University, Oldenburg, Germany, Oldenburg, Niedersachsen (Germany); Willborn, K [Pius Hospital Oldenburg, Oldenburg, Niedersachsen (Germany)

    2014-06-01

    Purpose: This study was undertaken to optimize the measurement techniques with radiochromic EBT3 films to offer accurate surface dose measurements and at the same time high resolution depth dose curves of the backscattering from high Z materials. Methods: Radiochromic EBT3 films (Ashland ISP, Wayne, USA) were wrapped around a PET hollow cylinder with a diameter of 41.5 mm and fixed upon the surface of a lead block. The setup was immersed in water and exposed to a dose of 2 Gy at 6MV acceleration voltage using a Siemens Primus linear accelerator. Water reference measurements were undertaken under equal conditions. An Epson Expression 10000 XL flatbed scanner (Epson, Suwa, Japan) with a preset resolution of 72 dpi was used for digitization. Results: The dose enhancement could be measured with a high resolution of measurement points along the axis normal to the lead surface. A dose enhancement of 70 % was measured at a distance of 134 ?m from the lead surface. The data has been compared with results presented by Das et al (Med. Phys. 16(3) (1989)) and is consistent within the uncertainty of the measurements. The results are in consistence with the results from time-tested EBT3 setups, i.e. normal-to-beam EBT3 film stacks and parallel to beam EBT3-films. Conclusion: The cylindrical film setup offers a powerful tool for surface measurements. The advantages of a stacked film setup and a parallel to beam setup could be combined.

  18. Anatomy-Based Algorithms for Detecting Oral Cancer Using Reflectance and Fluorescence Spectroscopy

    E-Print Network [OSTI]

    McGee, Sasha

    OBJECTIVES: We used reflectance and fluorescence spectroscopy to noninvasively and quantitatively distinguish benign from dysplastic/malignant oral lesions. We designed diagnostic algorithms to account for differences in ...

  19. Consequences of low dose ionizing radiation exposure on the hippocampal microenvironment

    E-Print Network [OSTI]

    2015-01-01

    June 4, 2015 Low Dose Radiation Alters HippocampalJune 4, 2015 Low Dose Radiation Alters HippocampalJune 4, 2015 Low Dose Radiation Alters Hippocampal

  20. TU-F-17A-08: The Relative Accuracy of 4D Dose Accumulation for Lung Radiotherapy Using Rigid Dose Projection Versus Dose Recalculation On Every Breathing Phase

    SciTech Connect (OSTI)

    Lamb, J; Lee, C; Tee, S; Lee, P; Iwamoto, K; Low, D; Valdes, G; Robinson, C

    2014-06-15

    Purpose: To investigate the accuracy of 4D dose accumulation using projection of dose calculated on the end-exhalation, mid-ventilation, or average intensity breathing phase CT scan, versus dose accumulation performed using full Monte Carlo dose recalculation on every breathing phase. Methods: Radiotherapy plans were analyzed for 10 patients with stage I-II lung cancer planned using 4D-CT. SBRT plans were optimized using the dose calculated by a commercially-available Monte Carlo algorithm on the end-exhalation 4D-CT phase. 4D dose accumulations using deformable registration were performed with a commercially available tool that projected the planned dose onto every breathing phase without recalculation, as well as with a Monte Carlo recalculation of the dose on all breathing phases. The 3D planned dose (3D-EX), the 3D dose calculated on the average intensity image (3D-AVE), and the 4D accumulations of the dose calculated on the end-exhalation phase CT (4D-PR-EX), the mid-ventilation phase CT (4D-PR-MID), and the average intensity image (4D-PR-AVE), respectively, were compared against the accumulation of the Monte Carlo dose recalculated on every phase. Plan evaluation metrics relating to target volumes and critical structures relevant for lung SBRT were analyzed. Results: Plan evaluation metrics tabulated using 4D-PR-EX, 4D-PR-MID, and 4D-PR-AVE differed from those tabulated using Monte Carlo recalculation on every phase by an average of 0.14±0.70 Gy, - 0.11±0.51 Gy, and 0.00±0.62 Gy, respectively. Deviations of between 8 and 13 Gy were observed between the 4D-MC calculations and both 3D methods for the proximal bronchial trees of 3 patients. Conclusions: 4D dose accumulation using projection without re-calculation may be sufficiently accurate compared to 4D dose accumulated from Monte Carlo recalculation on every phase, depending on institutional protocols. Use of 4D dose accumulation should be considered when evaluating normal tissue complication probabilities as well as in clinical situations where target volumes are directly inferior to mobile critical structures.

  1. CRYSTALLINE CERAMIC WASTE FORMS: REFERENCE FORMULATION REPORT

    SciTech Connect (OSTI)

    Brinkman, K.; Fox, K.; Marra, J.

    2012-05-15

    The research conducted in this work package is aimed at taking advantage of the long term thermodynamic stability of crystalline ceramics to create more durable waste forms (as compared to high level waste glass) in order to reduce the reliance on engineered and natural barrier systems. Durable ceramic waste forms that incorporate a wide range of radionuclides have the potential to broaden the available disposal options and to lower the storage and disposal costs associated with advanced fuel cycles. Assemblages of several titanate phases have been successfully demonstrated to incorporate radioactive waste elements, and the multiphase nature of these materials allows them to accommodate variation in the waste composition. Recent work has shown that they can be successfully produced from a melting and crystallization process. The objective of this report is to explain the design of ceramic host systems culminating in a reference ceramic formulation for use in subsequent studies on process optimization and melt property data assessment in support of FY13 melter demonstration testing. The waste stream used as the basis for the development and testing is a combination of the projected Cs/Sr separated stream, the Trivalent Actinide - Lanthanide Separation by Phosphorous reagent Extraction from Aqueous Komplexes (TALSPEAK) waste stream consisting of lanthanide fission products, the transition metal fission product waste stream resulting from the transuranic extraction (TRUEX) process, and a high molybdenum concentration with relatively low noble metal concentrations. In addition to the combined CS/LN/TM High Mo waste stream, variants without Mo and without Mo and Zr were also evaluated. Based on the results of fabricating and characterizing several simulated ceramic waste forms, two reference ceramic waste form compositions are recommended in this report. The first composition targets the CS/LN/TM combined waste stream with and without Mo. The second composition targets with CS/LN/TM combined waste stream with Mo and Zr removed. Waste streams that contain Mo must be produced in reducing environments to avoid Cs-Mo oxide phase formation. Waste streams without Mo have the ability to be melt processed in air. A path forward for further optimizing the processing steps needed to form the targeted phase assemblages is outlined in this report. Processing modifications including melting in a reducing atmosphere, and controlled heat treatment schedules are anticipated to improve the targeted elemental partitioning.

  2. SU-E-I-57: Evaluation and Optimization of Effective-Dose Using Different Beam-Hardening Filters in Clinical Pediatric Shunt CT Protocol

    SciTech Connect (OSTI)

    Gill, K; Aldoohan, S; Collier, J

    2014-06-01

    Purpose: Study image optimization and radiation dose reduction in pediatric shunt CT scanning protocol through the use of different beam-hardening filters Methods: A 64-slice CT scanner at OU Childrens Hospital has been used to evaluate CT image contrast-to-noise ratio (CNR) and measure effective-doses based on the concept of CT dose index (CTDIvol) using the pediatric head shunt scanning protocol. The routine axial pediatric head shunt scanning protocol that has been optimized for the intrinsic x-ray tube filter has been used to evaluate CNR by acquiring images using the ACR approved CT-phantom and radiation dose CTphantom, which was used to measure CTDIvol. These results were set as reference points to study and evaluate the effects of adding different filtering materials (i.e. Tungsten, Tantalum, Titanium, Nickel and Copper filters) to the existing filter on image quality and radiation dose. To ensure optimal image quality, the scanner routine air calibration was run for each added filter. The image CNR was evaluated for different kVps and wide range of mAs values using above mentioned beam-hardening filters. These scanning protocols were run under axial as well as under helical techniques. The CTDIvol and the effective-dose were measured and calculated for all scanning protocols and added filtration, including the intrinsic x-ray tube filter. Results: Beam-hardening filter shapes energy spectrum, which reduces the dose by 27%. No noticeable changes in image low contrast detectability Conclusion: Effective-dose is very much dependent on the CTDIVol, which is further very much dependent on beam-hardening filters. Substantial reduction in effective-dose is realized using beam-hardening filters as compare to the intrinsic filter. This phantom study showed that significant radiation dose reduction could be achieved in CT pediatric shunt scanning protocols without compromising in diagnostic value of image quality.

  3. Key ACA Terms A quick reference of frequently used terms

    E-Print Network [OSTI]

    Acton, Scott

    to achieving health care quality goals and outcomes that result in cost savings. Affordable Health Care Health; and pediatric services, including oral and vision care. Federal Poverty Level (FPL) A measure of income level issued annually by the Department of Health and Human Services. The federal poverty level is used

  4. WECC Variable Generation Planning Reference Book: Appendices

    SciTech Connect (OSTI)

    Makarov, Yuri V.; Du, Pengwei; Etingov, Pavel V.; Ma, Jian; Vyakaranam, Bharat

    2013-05-13

    The document titled “WECC Variable Generation Planning Reference Book”. This book is divided into two volumes; one is the main document (volume 1)and the other is appendices (volume 2). The main document is a collection of the best practices and the information regarding the application and impact of variables generation on power system planning. This volume (appendices) has additional information on the following topics: Probabilistic load flow problems. 2. Additional useful indices. 3. high-impact low-frequency (HILF) events. 4. Examples of wide-area nomograms. 5. Transmission line ratings, types of dynamic rating methods. 6. Relative costs per MW-km of different electric power transmission technologies. 7. Ultra-high voltage (UHV) transmission. 8.High voltage direct current (VSC-HVDC). 9. HVDC. 10. Rewiring of existing transmission lines. 11. High-temperature low sag (HTLS) conductors. 12. The direct method and energy functions for transient stability analysis in power systems. 13.Blackouts caused by voltage instability. 14. Algorithm for parameter continuation predictor-corrector methods. 15. Approximation techniques available for security regions. 16. Impacts of wind power on power system small signals stability. 17. FIDVR. 18. FACTS. 19. European planning standard and practices. 20. International experience in wind and solar energy sources. 21. Western Renewable Energy Zones (WREZ). 22. various energy storage technologies. 23. demand response. 24. BA consolidation and cooperation options. 25. generator power management requirements and 26. European planning guidelines.

  5. SAPHIRE 8 Volume 2 - Technical Reference

    SciTech Connect (OSTI)

    C. L. Smith; S. T. Wood; W. J. Galyean; J. A. Schroeder; M. B. Sattison

    2011-03-01

    The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) refers to a set of computer programs that were developed to create and analyze probabilistic risk assessment (PRAs). Herein information is provided on the principles used in the construction and operation of Version 8.0 of the SAPHIRE system. This report summarizes the fundamental mathematical concepts of sets and logic, fault trees, and probability. This volume then describes the algorithms used to construct a fault tree and to obtain the minimal cut sets. It gives the formulas used to obtain the probability of the top event from the minimal cut sets, and the formulas for probabilities that apply for various assumptions concerning reparability and mission time. It defines the measures of basic event importance that SAPHIRE can calculate. This volume gives an overview of uncertainty analysis using simple Monte Carlo sampling or Latin Hypercube sampling, and states the algorithms used by this program to generate random basic event probabilities from various distributions. Also covered are enhance capabilities such as seismic analysis, Workspace algorithms, cut set "recovery," end state manipulation, and use of "compound events."

  6. Dose reconstruction for real-time patient-specific dose estimation in CT

    SciTech Connect (OSTI)

    De Man, Bruno Yin, Zhye; Wu, Mingye; FitzGerald, Paul; Kalra, Mannudeep

    2015-05-15

    Purpose: Many recent computed tomography (CT) dose reduction approaches belong to one of three categories: statistical reconstruction algorithms, efficient x-ray detectors, and optimized CT acquisition schemes with precise control over the x-ray distribution. The latter category could greatly benefit from fast and accurate methods for dose estimation, which would enable real-time patient-specific protocol optimization. Methods: The authors present a new method for volumetrically reconstructing absorbed dose on a per-voxel basis, directly from the actual CT images. The authors’ specific implementation combines a distance-driven pencil-beam approach to model the first-order x-ray interactions with a set of Gaussian convolution kernels to model the higher-order x-ray interactions. The authors performed a number of 3D simulation experiments comparing the proposed method to a Monte Carlo based ground truth. Results: The authors’ results indicate that the proposed approach offers a good trade-off between accuracy and computational efficiency. The images show a good qualitative correspondence to Monte Carlo estimates. Preliminary quantitative results show errors below 10%, except in bone regions, where the authors see a bigger model mismatch. The computational complexity is similar to that of a low-resolution filtered-backprojection algorithm. Conclusions: The authors present a method for analytic dose reconstruction in CT, similar to the techniques used in radiation therapy planning with megavoltage energies. Future work will include refinements of the proposed method to improve the accuracy as well as a more extensive validation study. The proposed method is not intended to replace methods that track individual x-ray photons, but the authors expect that it may prove useful in applications where real-time patient-specific dose estimation is required.

  7. 7. Flows in a rotating reference frame 7.1. Rotating reference frames

    E-Print Network [OSTI]

    Read, Peter L.

    in a rotating reference frame. We use rotating axes, fixed w.r.t. the rotating system but note that time-derivatives of vectors must be modified: 1 #12;Suppose frame R rotates at constant angular velocity = (0, 0, ) w.r.t. an inertial frame I. Consider vector A(t) ­ suppose for simplicity that it lies in the xy-plane of R and I

  8. Shared dosimetry error in epidemiological dose-response analyses

    SciTech Connect (OSTI)

    Stram, Daniel O.; Preston, Dale L.; Sokolnikov, Mikhail; Napier, Bruce; Kopecky, Kenneth J.; Boice, John; Beck, Harold; Till, John; Bouville, Andre; Zeeb, Hajo

    2015-03-23

    Radiation dose reconstruction systems for large-scale epidemiological studies are sophisticated both in providing estimates of dose and in representing dosimetry uncertainty. For example, a computer program was used by the Hanford Thyroid Disease Study to provide 100 realizations of possible dose to study participants. The variation in realizations reflected the range of possible dose for each cohort member consistent with the data on dose determinates in the cohort. Another example is the Mayak Worker Dosimetry System 2013 which estimates both external and internal exposures and provides multiple realizations of "possible" dose history to workers given dose determinants. This paper takes up the problem of dealing with complex dosimetry systems that provide multiple realizations of dose in an epidemiologic analysis. In this paper we derive expected scores and the information matrix for a model used widely in radiation epidemiology, namely the linear excess relative risk (ERR) model that allows for a linear dose response (risk in relation to radiation) and distinguishes between modifiers of background rates and of the excess risk due to exposure. We show that treating the mean dose for each individual (calculated by averaging over the realizations) as if it was true dose (ignoring both shared and unshared dosimetry errors) gives asymptotically unbiased estimates (i.e. the score has expectation zero) and valid tests of the null hypothesis that the ERR slope ? is zero. Although the score is unbiased the information matrix (and hence the standard errors of the estimate of ?) is biased for ??0 when ignoring errors in dose estimates, and we show how to adjust the information matrix to remove this bias, using the multiple realizations of dose. The use of these methods in the context of several studies including, the Mayak Worker Cohort, and the U.S. Atomic Veterans Study, is discussed.

  9. Shared dosimetry error in epidemiological dose-response analyses

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Stram, Daniel O.; Preston, Dale L.; Sokolnikov, Mikhail; Napier, Bruce; Kopecky, Kenneth J.; Boice, John; Beck, Harold; Till, John; Bouville, Andre; Zeeb, Hajo

    2015-03-23

    Radiation dose reconstruction systems for large-scale epidemiological studies are sophisticated both in providing estimates of dose and in representing dosimetry uncertainty. For example, a computer program was used by the Hanford Thyroid Disease Study to provide 100 realizations of possible dose to study participants. The variation in realizations reflected the range of possible dose for each cohort member consistent with the data on dose determinates in the cohort. Another example is the Mayak Worker Dosimetry System 2013 which estimates both external and internal exposures and provides multiple realizations of "possible" dose history to workers given dose determinants. This paper takesmore »up the problem of dealing with complex dosimetry systems that provide multiple realizations of dose in an epidemiologic analysis. In this paper we derive expected scores and the information matrix for a model used widely in radiation epidemiology, namely the linear excess relative risk (ERR) model that allows for a linear dose response (risk in relation to radiation) and distinguishes between modifiers of background rates and of the excess risk due to exposure. We show that treating the mean dose for each individual (calculated by averaging over the realizations) as if it was true dose (ignoring both shared and unshared dosimetry errors) gives asymptotically unbiased estimates (i.e. the score has expectation zero) and valid tests of the null hypothesis that the ERR slope ? is zero. Although the score is unbiased the information matrix (and hence the standard errors of the estimate of ?) is biased for ??0 when ignoring errors in dose estimates, and we show how to adjust the information matrix to remove this bias, using the multiple realizations of dose. The use of these methods in the context of several studies including, the Mayak Worker Cohort, and the U.S. Atomic Veterans Study, is discussed.« less

  10. Evidence for formation of DNA repair centers and dose-response non-linearity in human cells

    E-Print Network [OSTI]

    Neumaier, Teresa

    2013-01-01

    exposure to low doses of ionizing radiation. Mutat Res 683(high doses to low doses of ionizing radiation. However, ourhypothesize that low doses of ionizing radiation induce a

  11. International linear collider reference design report

    SciTech Connect (OSTI)

    Aarons, G.

    2007-06-22

    The International Linear Collider will give physicists a new cosmic doorway to explore energy regimes beyond the reach of today's accelerators. A proposed electron-positron collider, the ILC will complement the Large Hadron Collider, a proton-proton collider at the European Center for Nuclear Research (CERN) in Geneva, Switzerland, together unlocking some of the deepest mysteries in the universe. With LHC discoveries pointing the way, the ILC -- a true precision machine -- will provide the missing pieces of the puzzle. Consisting of two linear accelerators that face each other, the ILC will hurl some 10 billion electrons and their anti-particles, positrons, toward each other at nearly the speed of light. Superconducting accelerator cavities operating at temperatures near absolute zero give the particles more and more energy until they smash in a blazing crossfire at the centre of the machine. Stretching approximately 35 kilometres in length, the beams collide 14,000 times every second at extremely high energies -- 500 billion-electron-volts (GeV). Each spectacular collision creates an array of new particles that could answer some of the most fundamental questions of all time. The current baseline design allows for an upgrade to a 50-kilometre, 1 trillion-electron-volt (TeV) machine during the second stage of the project. This reference design provides the first detailed technical snapshot of the proposed future electron-positron collider, defining in detail the technical parameters and components that make up each section of the 31-kilometer long accelerator. The report will guide the development of the worldwide R&D program, motivate international industrial studies and serve as the basis for the final engineering design needed to make an official project proposal later this decade.

  12. Comparison of low and high dose ionising radiation using topological analysis of gene coexpression networks

    E-Print Network [OSTI]

    Ray, Monika; Yunis, Reem; Chen, Xiucui; Rocke, David M

    2012-01-01

    gene networks for low-dose radiation using graph theoreticalthe detrimental effects of low dose radiation is not wellfollowing 10 cGy (low dose radiation) and 100 cGy (high dose

  13. Oral Health in North Carolina 1 March 2012 Satomi Imai, Ph. D.

    E-Print Network [OSTI]

    Gopalakrishnan, K.

    Oral Health in North Carolina 1 March 2012 Satomi Imai, Ph. D. Center for Health Systems Research and Development East Carolina University Oral Health in North Carolina: Regional and Demographic Disparities in North Carolina. Data for the report were collected by the North Carolina Behavioral Risk Factors

  14. Chemistry & Biology Power of tRNA Fragments, Journey into the Oral

    E-Print Network [OSTI]

    Chemistry & Biology Select Power of tRNA Fragments, Journey into the Oral Cavity Microbiome-cancer role, insights into what happens when one bacteria is selectively knocked out of the human oral cavity://dx.doi.org/10.1016/j.cell.2015.02.053 Ecosystem of the Human Mouth Every human being is not an individual

  15. Data Protection Statement The GAA Oral History Project aims to record the fullest possible picture of

    E-Print Network [OSTI]

    Huang, Jianyu

    , dissertation or similar research. · Publication worldwide on the internet. The entire GAA Oral History ProjectData Protection Statement The GAA Oral History Project aims to record the fullest possible picture History Project is requesting that people fill out one of the questionnaires or send the project a letter

  16. ALL-PATHWAYS DOSE ANALYSIS FOR THE PORTSMOUTH ON-SITE WASTE DISPOSAL FACILITY

    SciTech Connect (OSTI)

    Smith, F.; Phifer, M.

    2014-04-10

    A Portsmouth On-Site Waste Disposal Facility (OSWDF) All-Pathways analysis has been conducted that considers the radiological impacts to a resident farmer. It is assumed that the resident farmer utilizes a farm pond contaminated by the OSWDF to irrigate a garden and pasture and water livestock from which food for the resident farmer is obtained, and that the farmer utilizes groundwater from the Berea sandstone aquifer for domestic purposes (i.e. drinking water and showering). As described by FBP 2014b the Hydrologic Evaluation of Landfill Performance (HELP) model (Schroeder et al. 1994) and the Surface Transport Over Multiple Phases (STOMP) model (White and Oostrom 2000, 2006) were used to model the flow and transport from the OSWDF to the Points of Assessment (POAs) associated with the 680-ft elevation sandstone layer (680 SSL) and the Berea sandstone aquifer. From this modeling the activity concentrations radionuclides were projected over time at the POAs. The activity concentrations were utilized as input to a GoldSimTM (GTG 2010) dose model, described herein, in order to project the dose to a resident farmer over time. A base case and five sensitivity cases were analyzed. The sensitivity cases included an evaluation of the impacts of using a conservative inventory, an uncased well to the Berea sandstone aquifer, a low waste zone uranium distribution coefficient (Kd), different transfer factors, and reference person exposure parameters (i.e. at 95 percentile). The maximum base case dose within the 1,000 year assessment period was projected to be 1.5E-14 mrem/yr, and the maximum base case dose at any time less than 10,000 years was projected to be 0.002 mrem/yr. The maximum projected dose of any sensitivity case was approximately 2.6 mrem/yr associated with the use of an uncased well to the Berea sandstone aquifer. This sensitivity case is considered very unlikely because it assumes leakage from the location of greatest concentration in the 680 SSL in to the Berea sandstone aquiver over time and does not conform to standard private water well construction practices. The bottom-line is that all predicted doses from the base case and five sensitivity cases fall well below the DOE all-pathways 25 mrem/yr Performance Objective.

  17. Radiation Dose Risk and Diagnostic Benefit in Imaging Investigations

    E-Print Network [OSTI]

    Dobrescu, Lidia

    2015-01-01

    The paper presents many facets of medical imaging investigations radiological risks. The total volume of prescribed medical investigations proves a serious lack in monitoring and tracking of the cumulative radiation doses in many health services. Modern radiological investigations equipment is continuously reducing the total dose of radiation due to improved technologies, so a decrease in per caput dose can be noticed, but the increasing number of investigations has determined a net increase of the annual collective dose. High doses of radiation are cumulated from Computed Tomography investigations. An integrated system for radiation safety of the patients investigated by radiological imaging methods, based on smart cards and Public Key Infrastructure allow radiation absorbed dose data storage.

  18. SU-E-T-315: The Change of Optically Stimulated Luminescent Dosimeters (OSLDs) Sensitivity by Accumulated Dose and High Dose

    SciTech Connect (OSTI)

    Han, S; Jung, H; Kim, M; Ji, Y; Kim, K [University of Science and Technology, Daejeon (Korea, Republic of); Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of); Choi, S; Park, S; Yoo, H [Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of); Yi, C [Korea Research Institute of Standards and Science, Daejeon (Korea, Republic of)

    2014-06-01

    Purpose: The objective of this study is to evaluate radiation sensitivity of optical stimulated luminance dosimeters (OSLDs) by accumulated dose and high dose. Methods: This study was carried out in Co-60 unit (Theratron 780, AECL, and Canada) and used InLight MicroStar reader (Landauer, Inc., Glenwood, IL) for reading. We annealed for 30 min using optical annealing system which contained fluorescent lamps (Osram lumilux, 24 W, 280 ?780 nm). To evaluate change of OSLDs sensitivity by repeated irradiation, the dosimeters were repeatedly irradiated with 1 Gy. And whenever a repeated irradiation, we evaluated OSLDs sensitivity. To evaluate OSLDs sensitivity after accumulated dose with 5 Gy, We irradiated dose accumulatively (from 1 Gy to 5 Gy) without annealing. And OSLDs was also irradiated with 15, 20, 30 Gy to certify change of OSLDs sensitivity after high dose irradiation. After annealing them, they were irradiated with 1Gy, repeatedly. Results: The OSLDs sensitivity increased up to 3% during irradiating seven times and decreased continuously above 8 times. That dropped by about 0.35 Gy per an irradiation. Finally, after 30 times irradiation, OSLDs sensitivity decreased by about 7%. For accumulated dose from 1 Gy to 5 Gy, OSLDs sensitivity about 1 Gy increased until 4.4% after second times accumulated dose compared with before that. OSLDs sensitivity about 1 Gy decreased by 1.6% in five times irradiation. When OSLDs were irradiated ten times with 1Gy after irradiating high dose (10, 15, 20 Gy), OSLDs sensitivity decreased until 6%, 9%, 12% compared with it before high dose irradiation, respectively. Conclusion: This study certified OSLDs sensitivity by accumulated dose and high dose. When irradiated with 1Gy, repeatedly, OSLDs sensitivity decreased linearly and the reduction rate of OSLDs sensitivity after high dose irradiation had dependence on irradiated dose.

  19. Radiation dose rates from UF{sub 6} cylinders

    SciTech Connect (OSTI)

    Friend, P.J. [Urenco, Capenhurst (United Kingdom)

    1991-12-31

    This paper describes the results of many studies, both theoretical and experimental, which have been carried out by Urenco over the last 15 years into radiation dose rates from uranium hexafluoride (UF{sub 6}) cylinders. The contents of the cylinder, its history, and the geometry all affect the radiation dose rate. These factors are all examined in detail. Actual and predicted dose rates are compared with levels permitted by IAEA transport regulations.

  20. Web-Based Training on Reviewing Dose Modeling Aspects of NRC Decommissioning and License Termination Plans

    SciTech Connect (OSTI)

    LePoire, D.; Cheng, J.J.; Kamboj, S.; Arnish, J.; Richmond, P.; Chen, S.Y.; Barr, C.; McKenney, C.

    2008-01-15

    NRC licensees at decommissioning nuclear facilities submit License Termination Plans (LTP) or Decommissioning Plans (DP) to NRC for review and approval. To facilitate a uniform and consistent review of these plans, the NRC developed training for its staff. A live classroom course was first developed in 2005, which targeted specific aspects of the LTP and DP review process related to dose-based compliance demonstrations or modeling. A web-based training (WBT) course was developed in 2006 and 2007 to replace the classroom-based course. The advantage of the WBT is that it will allow for staff training or refreshers at any time, while the advantage of a classroom-based course is that it provides a forum for lively discussion and the sharing of experience of classroom participants. The objective of this course is to train NRC headquarters and regional office staff on how to review sections of a licensee's DP or LTP that pertain to dose modeling. The DP generally refers to the decommissioning of non-reactor facilities, while the LTP refers specifically to the decommissioning of reactors. This review is part of the NRC's licensing process, in which the NRC determines if a licensee has provided a suitable technical basis to support derived concentration guideline levels (DCGLs)1 or dose modeling analyses performed to demonstrate compliance with dose-based license termination rule criteria. This type of training is one component of an organizational management system. These systems 'use a range of practices to identify, create, represent, and distribute knowledge for reuse, awareness and learning'. This is especially important in an organization undergoing rapid change or staff turnover to retain organizational information and processes. NRC is committed to maintaining a dynamic program of training, development, and knowledge transfer to ensure that the NRC acquires and maintains the competencies needed to accomplish its mission. This paper discusses one specific project related to training, developing, and transferring knowledge to NRC staff on how to review dose-modeling portions of licensee-submitted DPs and LTPs. This project identified specific cases and examples, created easily updateable educational modules, represented material in an engaging format through animations, video, and graphics, and distributed information on how to perform these reviews in an accessible, web-based format. WBT promotes consistency in reviews and has the advantage of being able to be used as a resource to staff at any time. The WBT will provide reviewers with knowledge needed to perform risk-informed analyses (e.g., information related to development of realistic scenarios and use of probabilistic analysis). WBT on review of LTP or DP dose modeling will promote staff development, efficiency, and effectiveness in performing risk-informed, performance-based reviews of decommissioning activities at NRC-licensed facilities. One of the key advantages of this type of web-based training is that it can be loaded on-demand and can be reused indefinitely. In addition to the benefits of on-demand training, the modules can also be used for reference. The presentations are hosted on a web server that can be accessed by registered users at any time. Staff can return to a particular module to review the material long after they have completed the course.

  1. Ground-water contribution to dose from past Hanford Operations. Hanford Environmental Dose Reconstruction Project

    SciTech Connect (OSTI)

    Freshley, M.D.; Thorne, P.D.

    1992-08-01

    The Hanford Environmental Dose Reconstruction (HEDR) Project is being conducted to estimate radiation doses that populations and individuals could have received from Hanford Site operations from 1944 to the present. Four possible pathways by which radionuclides migrating in ground water on the Hanford Site could have reached the public have been identified: (1) through contaminated ground water migrating to the Columbia River; (2) through wells on or adjacent to the Hanford Site; (3) through wells next to the Columbia River downstream of Hanford that draw some or all of their water from the river (riparian wells); and (4) through atmospheric deposition resulting in contamination of a small watershed that, in turn, results in contamination of a shallow well or spring by transport in the ground water. These four pathways make up the ``ground-water pathway,`` which is the subject of this study. Assessment of the ground-water pathway was performed by (1) reviewing the existing extensive literature on ground water and ground-water monitoring at Hanford and (2) performing calculations to estimate radionuclide concentrations where no monitoring data were collected. Radiation doses that would result from exposure to these radionuclides were calculated.

  2. Radiation Therapy Photon Beams Dose Conformation According to Dose Distribution Around Intracavitary-Applied Brachytherapy Sources

    SciTech Connect (OSTI)

    Jurkovic, Slaven Zauhar, Gordana; Faj, Dario; Radojcic, Deni Smilovic; Svabic, Manda

    2010-04-01

    Intracavitary application of brachytherapy sources followed by external beam radiation is essential for the local treatment of carcinoma of the cervix. Due to very high doses to the central portion of the target volume delivered by brachytherapy sources, this part of the target volume must be shielded while being irradiated by photon beams. Several shielding techniques are available, from rectangular block and standard cervix wedge to more precise, customized step wedge filters. Because the calculation of a step wedge filter's shape was usually based on effective attenuation coefficient, an approach that accounts, in a more precise way, for the scattered radiation, is suggested. The method was verified under simulated clinical conditions using film dosimetry. Measured data for various compensators were compared to the numerically determined sum of the dose distribution around brachytherapy sources and one of compensated beam. Improvements in total dose distribution are demonstrated, using our method. Agreement between calculation and measurements were within 3%. Sensitivity of the method on sources displacement during treatment has also been investigated.

  3. Reduction of aspirin-induced fecal blood loss with low-dose misoprostol tablets in man

    SciTech Connect (OSTI)

    Cohen, M.M.; Clark, L.; Armstrong, L.; D'Souza, J.

    1985-07-01

    Misoprostol (SC-29333), a synthetic prostaglandin E1 methyl ester analog, was given simultaneously with acetylsalicylic acid in a double-blind, placebo-controlled randomized prospective study of 32 healthy human male subjects. Fecal blood loss was measured for eight days using the /sup 51/Cr-labeled red blood cell technique. Aspirin (650 mg qid) and misoprostol (25 micrograms qid) or placebo were given during days 3, 4, and 5. There was a significant (P less than 0.05) increase in median blood loss (modified Friedman test) from 0.81 to 6.05 ml/day in the aspirin with placebo group (N = 16). Median blood loss was increased (from 0.75 to 3.75 ml/day) in the aspirin with misoprostol group (N = 16), but this was significantly less (Mann-Whitney U test, P less than 0.01) than the placebo group. Mean serum salicylate concentrations in the placebo and misoprostol groups were similar (7.8 and 6.8 micrograms/ml, respectively). There were no significant changes in laboratory values in any of the subjects studied, nor were any major side-effects encountered. This study demonstrates that oral misoprostol reduces aspirin-induced gastrointestinal bleeding even when administered simultaneously and at a dose level below its threshold for significant acid inhibition. This indicates a potential role for misoprostol in the prevention of gastric mucosal damage in selected patients.

  4. Ten Steps for Career Success Ready Reference A-4

    E-Print Network [OSTI]

    Ten Steps for Career Success Ready Reference A-4 College of Engineering, Architecture & Technology Career Services Oklahoma State University College of Engineering, Architecture & Technology Career

  5. Sample Letter of Inquiry Ready Reference F-4

    E-Print Network [OSTI]

    Sample Letter of Inquiry Ready Reference F-4 College of Engineering, Architecture & Technology Career Services Oklahoma State University College of Engineering, Architecture & Technology Career

  6. First Impressions on Job Interviews Ready Reference G-2

    E-Print Network [OSTI]

    & Technology Career Services Oklahoma State University College of Engineering, Architecture & TechnologyFirst Impressions on Job Interviews Ready Reference G-2 College of Engineering, Architecture

  7. Sample Status Inquiry Letter Ready Reference F-9

    E-Print Network [OSTI]

    Sample Status Inquiry Letter Ready Reference F-9 College of Engineering, Architecture & Technology Career Services Oklahoma State University College of College of Engineering, Architecture & Technology

  8. Bibliography of the Scripps Institution of Oceanography Reference Series 1999

    E-Print Network [OSTI]

    Jennings, Paige A.

    2000-01-01

    SCRIPPS INSTITUTION OF OCEANOGRAPHY REFERENCE SERIES 99-1Scripps Institution of Oceanography. April 1999. 55p. 99-11the Scripps Institution of Oceanography. Originally printed

  9. Bibliography of the Scripps Institution of Oceanography Reference Series 2002

    E-Print Network [OSTI]

    Lett, Phyllis C.

    2003-01-01

    Scripps Institution of Oceanography Reference Series. MarchSCRIPPS INSTITUTION OF OCEANOGRAPHY LA JOLL~ CALIFORNIAOF THE SCRIPPS INSTITUTION OF OCEANOGRAPHY REF ERENCE SERIES

  10. Bibliography of the Scripps Institution of Oceanography Reference Series 1995

    E-Print Network [OSTI]

    Criqui, Nan P.

    1995-01-01

    Scripps Institution of Oceanography. August 1995. 353p. 95-OF THE SCRIPPS INSTITUTION OF OCEANOGRAPHY REFERENCE SERIESScripps Institution of Oceanography. January 1995. 10p. Day,

  11. Existing Commercial Reference Buildings Constructed In or After 1980 — Archive

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the commercial reference building models for existing buildings constructed in or after 1980, organized by building type and location.

  12. MPI: The Complete Reference Scientific and Engineering Computation

    E-Print Network [OSTI]

    Lu, Paul

    MPI: The Complete Reference #12; Scientific and Engineering Computation Janusz Kowalik, Editor Data Manchek, and Vaidy Sunderam, 1994 Enabling Technologies for Petaflops Computing by Thomas Sterling, Paul

  13. Reference Model for Control and Automation Systems in Electrical...

    Office of Environmental Management (EM)

    Reference Model for Control and Automation Systems in Electrical Power Version 1.2 October 12, 2005 Prepared by: Sandia National Laboratories' Center for SCADA Security Jason...

  14. Reference Model for Control and Automation Systems in Electrical...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Model for Control and Automation Systems in Electrical Power (October 2005) Reference Model for Control and Automation Systems in Electrical Power (October 2005) Modern...

  15. H2FIRST Reference Station Design Task: Project Deliverable 2...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    98 List of Tables Table ES-1. Station Types Selected for Detailed Reference Design Development ... v Table 1. Changed Input Parameters...

  16. Plutonium Certified Reference Materials Price List | U.S. DOE...

    Office of Science (SC) Website

    Laboratory (NBL) NBL Home About Programs Certified Reference Materials (CRMs) Prices and Certificates Ordering Information Training NEPA Documents News Safety Data Sheets...

  17. NERSC/DOE FES Requirements Workshop Reference Materials

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Materials Reference Materials Large Scale Computing and Storage Requirements for Fusion Energy Sciences August 3-4, 2010 Official DOE Invitation Workshop Invitation Letter from...

  18. FAQS Reference Guide – Safeguards and Security General Technical Base

    Office of Energy Efficiency and Renewable Energy (EERE)

    This reference guide addresses the competency statements in the July 2009 edition of DOE-STD-1123-2009, Safeguards and Security General Technical Base Qualification Standard.

  19. Sandia Energy - Floating Oscillating Water Column Reference Model...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    to provide publicly available technical and economic benchmarks for a variety of marine energy converters. The final reference model, an oscillating water column (OWC)...

  20. Improvements in dose calculation accuracy for small off-axis targets in high dose per fraction tomotherapy

    SciTech Connect (OSTI)

    Hardcastle, Nicholas; Bayliss, Adam; Wong, Jeannie Hsiu Ding; Rosenfeld, Anatoly B.; Tome, Wolfgang A.

    2012-08-15

    Purpose: A recent field safety notice from TomoTherapy detailed the underdosing of small, off-axis targets when receiving high doses per fraction. This is due to angular undersampling in the dose calculation gantry angles. This study evaluates a correction method to reduce the underdosing, to be implemented in the current version (v4.1) of the TomoTherapy treatment planning software. Methods: The correction method, termed 'Super Sampling' involved the tripling of the number of gantry angles from which the dose is calculated during optimization and dose calculation. Radiochromic film was used to measure the dose to small targets at various off-axis distances receiving a minimum of 21 Gy in one fraction. Measurements were also performed for single small targets at the center of the Lucy phantom, using radiochromic film and the dose magnifying glass (DMG). Results: Without super sampling, the peak dose deficit increased from 0% to 18% for a 10 mm target and 0% to 30% for a 5 mm target as off-axis target distances increased from 0 to 16.5 cm. When super sampling was turned on, the dose deficit trend was removed and all peak doses were within 5% of the planned dose. For measurements in the Lucy phantom at 9.7 cm off-axis, the positional and dose magnitude accuracy using super sampling was verified using radiochromic film and the DMG. Conclusions: A correction method implemented in the TomoTherapy treatment planning system which triples the angular sampling of the gantry angles used during optimization and dose calculation removes the underdosing for targets as small as 5 mm diameter, up to 16.5 cm off-axis receiving up to 21 Gy.

  1. SU-E-J-243: Possibility of Exposure Dose Reduction of Cone-Beam Computed Tomography in An Image Guided Patient Positioning System by Using Various Noise Suppression Filters

    SciTech Connect (OSTI)

    Kamezawa, H; Arimura, H; Ohki, M; Shirieda, K; Kameda, N

    2014-06-01

    Purpose: To investigate the possibility of exposure dose reduction of the cone-beam computed tomography (CBCT) in an image guided patient positioning system by using 6 noise suppression filters. Methods: First, a reference dose (RD) and low-dose (LD)-CBCT (X-ray volume imaging system, Elekta Co.) images were acquired with a reference dose of 86.2 mGy (weighted CT dose index: CTDIw) and various low doses of 1.4 to 43.1 mGy, respectively. Second, an automated rigid registration for three axes was performed for estimating setup errors between a planning CT image and the LD-CBCT images, which were processed by 6 noise suppression filters, i.e., averaging filter (AF), median filter (MF), Gaussian filter (GF), bilateral filter (BF), edge preserving smoothing filter (EPF) and adaptive partial median filter (AMF). Third, residual errors representing the patient positioning accuracy were calculated as an Euclidean distance between the setup error vectors estimated using the LD-CBCT image and RD-CBCT image. Finally, the relationships between the residual error and CTDIw were obtained for 6 noise suppression filters, and then the CTDIw for LD-CBCT images processed by the noise suppression filters were measured at the same residual error, which was obtained with the RD-CBCT. This approach was applied to an anthropomorphic pelvic phantom and two cancer patients. Results: For the phantom, the exposure dose could be reduced from 61% (GF) to 78% (AMF) by applying the noise suppression filters to the CBCT images. The exposure dose in a prostate cancer case could be reduced from 8% (AF) to 61% (AMF), and the exposure dose in a lung cancer case could be reduced from 9% (AF) to 37% (AMF). Conclusion: Using noise suppression filters, particularly an adaptive partial median filter, could be feasible to decrease the additional exposure dose to patients in image guided patient positioning systems.

  2. Empowering the Frontline: A Dynamic Online Reference Manual and Training Session for Student Library Employee Reference Skills

    E-Print Network [OSTI]

    Loo, Jeffery L; Quigley, Brian D; Ngo, Lisa T; Powell, Susan; Teplitzky, Samantha

    2015-01-01

    training across our libraries’ service points. To developSession for Student Library Employee Reference SkillsTraining Design 5 libraries Engineering & Physical Sciences

  3. Physics Contribution Brachytherapy Application With In Situ Dose

    E-Print Network [OSTI]

    Sridhar, Srinivas

    Physics Contribution Brachytherapy Application With In Situ Dose Painting Administered by Gold-loaded brachytherapy spacers. Re- sults showed that dose enhancement to tumor voxels or subvolumes can be customized by varying the sizes of the released GNP and brachytherapy source type. These findings provide a useful basis

  4. Hanford Site Annual Report Radiological Dose Calculation Upgrade Evaluation

    SciTech Connect (OSTI)

    Snyder, Sandra F.

    2010-02-28

    Operations at the Hanford Site, Richland, Washington, result in the release of radioactive materials to offsite residents. Site authorities are required to estimate the dose to the maximally exposed offsite resident. Due to the very low levels of exposure at the residence, computer models, rather than environmental samples, are used to estimate exposure, intake, and dose. A DOS-based model has been used in the past (GENII version 1.485). GENII v1.485 has been updated to a Windows®-based software (GENII version 2.08). Use of the updated software will facilitate future dose evaluations, but must be demonstrated to provide results comparable to those of GENII v1.485. This report describes the GENII v1.485 and GENII v2.08 dose exposure, intake, and dose estimates for the maximally exposed offsite resident reported for calendar year 2008. The GENII v2.08 results reflect updates to implemented algorithms. No two environmental models produce the same results, as was again demonstrated in this report. The aggregated dose results from 2008 Hanford Site airborne and surface water exposure scenarios provide comparable dose results. Therefore, the GENII v2.08 software is recommended for future offsite resident dose evaluations.

  5. Calculation of dose to soft tisse from implanted beta sources 

    E-Print Network [OSTI]

    Dauffy, Lucile

    1998-01-01

    , spherical radioactive particles are injected into these arteries. This study deals with the development of BRAIN-DOSES, a computer code based on VARSKIN MOD2 and SADDE MOD2, which evaluates gamma and beta dose distributions for radioactive sources with five...

  6. INCIDENT CONTAMINATION LEPTON DOSES MEASURED USING RADIOCHROMIC FILM IN

    E-Print Network [OSTI]

    Yu, Peter K.N.

    INCIDENT CONTAMINATION LEPTON DOSES MEASURED USING RADIOCHROMIC FILM IN RADIOTHERAPY MARTIN J) AbstractÐMeasurement of lepton contamination is achieved across a radiotherapy photon beam and peripheral in air to measure incident contamination without the eects of phantom scatter. Surface dose was measured

  7. TESS-based dose-response using pediatric clonidine exposures

    SciTech Connect (OSTI)

    Benson, Blaine E. [New Mexico Poison and Drug Information Center and University of New Mexico College of Pharmacy, Albuquerque, NM 87131 (United States)]. E-mail: jebenson@salud.unm.edu; Spyker, Daniel A. [Alexza Pharmaceuticals, Palo Alto, CA 94303 (United States); Troutman, William G. [University of New Mexico College of Pharmacy, Albuquerque, NM 87131 (United States); Watson, William A. [American Association of Poison Control Centers, Washington, DC 20016 (United States)]. E-mail: http://www.aapcc.org/

    2006-06-01

    Objective: The toxic and lethal doses of clonidine in children are unclear. This study was designed to determine whether data from the American Association of Poison Control Centers Toxic Exposure Surveillance System (TESS) could be utilized to determine a dose-response relationship for pediatric clonidine exposure. Methods: 3458 single-substance clonidine exposures in children <6 years of age reported to TESS from January 2000 through December 2003 were examined. Dose ingested, age, and medical outcome were available for 1550 cases. Respiratory arrest cases (n = 8) were classified as the most severe of the medical outcome categories (Arrest, Major, Moderate, Mild, and No effect). Exposures reported as a 'taste or lick' (n = 51) were included as a dose of 1/10 of the dosage form involved. Dose ranged from 0.4 to 1980 (median 13) {mu}g/kg. Weight was imputed based on a quadratic estimate of weight for age. Dose certainty was coded as exact (26% of cases) or not exact (74%). Medical outcome (response) was examined via logistic regression using SAS JMP (release 5.1). Results: The logistic model describing medical outcome (P < 0.0001) included Log dose/kg (P 0.0000) and Certainty (P = 0.045). Conclusion: TESS data can provide the basis for a statistically sound description of dose-response for pediatric clonidine poisoning exposures.

  8. Archived Reference Building Type: Stand-alone retail

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the commercial reference building models for existing buildings constructed in or after 1980, organized by building type and location. A summary of building types and climate zones is available for reference. Current versions are also available.

  9. Archived Reference Building Type: Stand-alone retail

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the commercial reference building models for existing buildings constructed before 1980, organized by building type and location. A summary ofbuilding types and climate zones is available for reference. Current versions are also available.

  10. Archived Reference Climate Zone: 3C San Francisco, California

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the commercial reference building models for existing buildings constructed before 1980, organized by building type and location. A summary ofbuilding types and climate zones is available for reference. Current versions are also available.

  11. Archived Reference Climate Zone: 3C San Francisco, California

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the commercial reference building models for existing buildings constructed in or after 1980, organized by building type and location. A summary of building types and climate zones is available for reference. Current versions are also available.

  12. Archived Reference Climate Zone: 4A Baltimore, Maryland

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the commercial reference building models for existing buildings constructed before 1980, organized by building type and location. A summary ofbuilding types and climate zones is available for reference. Current versions are also available.

  13. Archived Reference Climate Zone: 4A Baltimore, Maryland

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the commercial reference building models for existing buildings constructed in or after 1980, organized by building type and location. A summary of building types and climate zones is available for reference. Current versions are also available.

  14. SQL Reference Learning Gupta SQLBase Structured Query Language

    E-Print Network [OSTI]

    SQL Reference Learning Gupta SQLBase Structured Query Language (SQL) By William Sprouse CENTER, CO 80523 Spring 1996 #12;SQL Reference Learning Gupta SQLBase Structured Query Language (SQL.1.2.4 The Clipboard 5 2.2 GETTING STARTED 5 2.2.1 STARTING QUEST 5 2.2.2 GETTING HELP 6 3. SQL BASICS 6 3

  15. DEGAS 2 Verification Test with Fluid Neutral Momentum Transport Reference

    E-Print Network [OSTI]

    Budny, Robert

    DEGAS 2 Verification Test with Fluid Neutral Momentum Transport Reference Problem D. P. Stotler, PPPL 1 Background The "Fluid Neutral Momentum Transport Reference Problem" [1] was used to verify the original DEGAS [2] Monte Carlo neutral transport code. The resulting benchmark was subsequently employed

  16. Archived Reference Climate Zone: 6A Minneapolis, Minnesota

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the commercial reference building models for existing buildings constructed before 1980, organized by building type and location. A summary ofbuilding types and climate zones is available for reference. Current versions are also available.

  17. Archived Reference Climate Zone: 6A Minneapolis, Minnesota

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the commercial reference building models for existing buildings constructed in or after 1980, organized by building type and location. A summary of building types and climate zones is available for reference. Current versions are also available.

  18. NIST STANDARD REFERENCE DATA (SRD) INTERNET SERVICE SUBSCRIPTION LICENSE

    E-Print Network [OSTI]

    NIST STANDARD REFERENCE DATA (SRD) INTERNET SERVICE SUBSCRIPTION LICENSE This document is a non-exclusive, non-transferrable, non-assignable and limited License Agreement (AGREEMENT) between the National ­ a person designated in the License to use the Internet Edition of a NIST Standard Reference Database under

  19. Dynamic Stochastic Inventory Management with Reference Price Effects

    E-Print Network [OSTI]

    Chen, Xin

    Dynamic Stochastic Inventory Management with Reference Price Effects Xin Chen Department in which demand depends on not only the current selling price but also a memory-based reference price. Pricing and inventory decisions are made simultane- ously at the beginning of each period. Assuming all

  20. Archived Reference Climate Zone: 2B Phoenix, Arizona

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the commercial reference building models for existing buildings constructed before 1980, organized by building type and location. A summary ofbuilding types and climate zones is available for reference. Current versions are also available.

  1. Archived Reference Climate Zone: 2B Phoenix, Arizona

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the commercial reference building models for existing buildings constructed in or after 1980, organized by building type and location. A summary of building types and climate zones is available for reference. Current versions are also available.

  2. Overview of Fluence to Dose Conversion Coefficients for High Energy Radiations - Calculational Methods and Results of Two Kinds of Effective Dose per Unit Particle Fluence

    E-Print Network [OSTI]

    Iwai, S; Sato, O; Yoshizawa, N; Furihata, S; Takagi, S; Tanaka, S; Sakamoto, Y

    2000-01-01

    Overview of Fluence to Dose Conversion Coefficients for High Energy Radiations - Calculational Methods and Results of Two Kinds of Effective Dose per Unit Particle Fluence

  3. Topographic Effects on Ambient Dose Equivalent Rates from Radiocesium Fallout

    E-Print Network [OSTI]

    Malins, Alex; Machida, Masahiko; Saito, Kimiaki

    2015-01-01

    Land topography can affect air radiation dose rates by locating radiation sources closer to, or further, from detector locations when compared to perfectly flat terrain. Hills and slopes can also shield against the propagation of gamma rays. To understand the possible magnitude of topographic effects on air dose rates, this study presents calculations for ambient dose equivalent rates at a range of heights above the ground for varying land topographies. The geometries considered were angled ground at the intersection of two planar surfaces, which is a model for slopes neighboring flat land, and a simple conical geometry, representing settings from hilltops to valley bottoms. In each case the radiation source was radioactive cesium fallout, and the slope angle was varied systematically to determine the effect of topography on the air dose rate. Under the assumption of homogeneous fallout across the land surface, and for these geometries and detector locations, the dose rates at high altitudes are more strongly...

  4. Communication between inertial observers with partially correlated reference frames

    E-Print Network [OSTI]

    Mehdi Ahmadi; Alexander R. H. Smith; Andrzej Dragan

    2015-08-13

    In quantum communication protocols the existence of a shared reference frame between two spatially separated parties is normally presumed. However, in many practical situations we are faced with the problem of misaligned reference frames. In this paper, we study communication between two inertial observers who have partial knowledge about the Lorentz transformation that relates their frames of reference. Since every Lorentz transformation can be decomposed into a pure boost followed by a rotation, we begin by analysing the effects on communication when the parties have partial knowledge about the transformation relating their frames, when the transformation is either a rotation or pure boost. This then enables us to investigate how the efficiency of communication is affected due to partially correlated inertial reference frames related by an arbitrary Lorentz transformation. Furthermore, we show how the results of previous studies where reference frames are completely uncorrelated are recovered from our results in appropriate limits.

  5. SU-E-J-175: Proton Dose Calculation On Scatter-Corrected CBCT Image: Feasibility Study for Adaptive Proton Therapy

    SciTech Connect (OSTI)

    Park, Y; Winey, B; Sharp, G

    2014-06-01

    Purpose: To demonstrate feasibility of proton dose calculation on scattercorrected CBCT images for the purpose of adaptive proton therapy. Methods: Two CBCT image sets were acquired from a prostate cancer patient and a thorax phantom using an on-board imaging system of an Elekta infinity linear accelerator. 2-D scatter maps were estimated using a previously introduced CT-based technique, and were subtracted from each raw projection image. A CBCT image set was then reconstructed with an open source reconstruction toolkit (RTK). Conversion from the CBCT number to HU was performed by soft tissue-based shifting with reference to the plan CT. Passively scattered proton plans were simulated on the plan CT and corrected/uncorrected CBCT images using the XiO treatment planning system. For quantitative evaluation, water equivalent path length (WEPL) was compared in those treatment plans. Results: The scatter correction method significantly improved image quality and HU accuracy in the prostate case where large scatter artifacts were obvious. However, the correction technique showed limited effects on the thorax case that was associated with fewer scatter artifacts. Mean absolute WEPL errors from the plans with the uncorrected and corrected images were 1.3 mm and 5.1 mm in the thorax case and 13.5 mm and 3.1 mm in the prostate case. The prostate plan dose distribution of the corrected image demonstrated better agreement with the reference one than that of the uncorrected image. Conclusion: A priori CT-based CBCT scatter correction can reduce the proton dose calculation error when large scatter artifacts are involved. If scatter artifacts are low, an uncorrected CBCT image is also promising for proton dose calculation when it is calibrated with the soft-tissue based shifting.

  6. Inspection and Gamma-Ray Dose Rate Measurements of the Annulus of the VSC-17 Concrete Spent Nuclear Fuel Storage Cask

    SciTech Connect (OSTI)

    P. L. Winston

    2007-09-01

    The air cooling annulus of the Ventilated Storage Cask (VSC)-17 spent fuel storage cask was inspected using a Toshiba 7 mm (1/4”) CCD video camera. The dose rates observed in the annular space were measured to provide a reference for the activity to which the camera(s) being tested were being exposed. No gross degradation, pitting, or general corrosion was observed.

  7. MAC -OUTLOOK QUICK TIP REFERENCE GUIDE 1 Quick Tip Reference Guide | Swinburne University of Technology Version 1.0

    E-Print Network [OSTI]

    Liley, David

    MAC - OUTLOOK QUICK TIP REFERENCE GUIDE 1 Quick Tip Reference Guide | Swinburne University of Technology Version 1.0 Managing Your Emails Conversation View in Outlook 2011 1. Click Organize tab 2. Click. On the Outlook menu, click Preferences. 2. Under E-mail, click Signatures . 3. Click Default Signatures. 4. Under

  8. Blue carbon storage potential of marine carbonate deposits Project reference IAP/13/50. Please quote this reference when applying.

    E-Print Network [OSTI]

    Guo, Zaoyang

    IAPETUS Blue carbon storage potential of marine carbonate deposits Project reference IAP/13 Henrik Stahl, Scottish Association for Marine Science Key Words 1. Blue carbon 2. Carbonate 3. Coralline is referred to as `blue carbon' to differentiate it from terrestrial carbon stores. Known blue carbon sinks

  9. Overview of vegetation monitoring data, 1952--1983. Hanford Environmental Dose Reconstruction Project

    SciTech Connect (OSTI)

    Duncan, J.P.

    1994-03-01

    This report is a result of the Hanford Environmental Dose Reconstruction (HEDR) Project. The goal of the HEDR Project is to estimate the radiation dose that individuals could have received from emissions since 1944 at the Hanford Site near Richland, Washington. Members of the HEDR Project`s Environmental Monitoring Data Task have developed databases of historical environmental measurements of such emissions. The HEDR Project is conducted by Battelle, Pacific Northwest Laboratories. This report is the third in a series that documents the information available on measurements of iodine-131 concentrations in vegetation. The first two reports provide the data for 1945--1951. This report provides an overview of the historical documents, which contain vegetation data for 1952--1983. The overview is organized according to the documents available for any given year. Each section, covering one year, contains a discussion of the media sampled, the sampling locations, significant events if there were any, emission quantities, constituents measured, and a list of the documents with complete reference information. Because the emissions which affected vegetation were significantly less after 1951, the vegetation monitoring data after that date have not been used in the HEDR Project. However, access to these data may be of interest to the public. This overview is, therefore, being published.

  10. Direct determination of radiation dose in human blood

    E-Print Network [OSTI]

    Tanir, Ayse Gunes; Sahiner, Eren; Bolukdemir, Mustafa Hicabi; Koc, Kemal; Meric, Niyazi; Kelec, Sule Kaya

    2014-01-01

    Our purpose is to measure the internal radiation dose (ID) using human blood sample. In the literature, there is no process that allows the direct measurement of ID received by a person. This study has shown that it is possible to determine ID in human blood exposed to internal or external ionizing radiation treatment both directly and retrospectively. OSL technique was used to measure the total dose from the blood sample. OSL counts from the waste blood of the patient injected with a radiopharmaceutical for diagnostic or treatment purposes and from a blood sample having a laboratory-injected radiation dose were both used for measurements. The decay and dose-response curves (DRC) were plotted for different doses. The doses received by different blood aliquots have been determined by interpolating the natural luminescence counts to DRC. In addition, OSL counts from a healthy blood sample exposed to an external radiation source were measured. The blood aliquots were given different 0-200Gy beta doses and their ...

  11. Transepithelial transport of nanoparticles targeted to the neonatal Fc receptor for oral delivery applications

    E-Print Network [OSTI]

    Pridgen, Eric M. (Eric Michael)

    2013-01-01

    Nanoparticles (NPs) are poised to have a tremendous impact on the treatment of many diseases, but their broad application is limited because currently they can only be administered by parenteral methods. Oral administration ...

  12. Tracking Reading: Dual Task Costs of Oral Reading for Young Versus Older Adults

    E-Print Network [OSTI]

    Kemper, Susan; Bontempo, Daniel; Schmalzried, RaLynn Cheri; McKedy, Whitney; Tagliaferri, Bruno; Kieweg, Doug

    2014-02-01

    A digital pursuit rotor was used to monitor oral reading costs by time-locking tracking performance to the auditory wave form produced as young and older adults were reading out short paragraphs. Multilevel modeling was ...

  13. Role of AI-2 in oral biofilm formation using microfluidic devices 

    E-Print Network [OSTI]

    Kim, Sun Ho

    2009-05-15

    Biofilms are highly organized bacterial structures that are attached to a surface. They are ubiquitous in nature and may be detrimental, causing numerous types of illnesses in living organisms. Biofilms in the human oral cavity are the main cause...

  14. An Investigation of the Demands on Oral Language Skills of Learning Disabled Students in Secondary Classrooms

    E-Print Network [OSTI]

    Moran, Mary Ross

    1980-01-01

    The demands placed upon students in mainstream secondary classrooms by the oral language behaviors of teachers were investigated by applying 12 categories of utterance types to audiotape-recorded class sessions. Data were ...

  15. Financial and nutrition outcomes for patients placed on enteral nutrition versus oral intake 

    E-Print Network [OSTI]

    Barry, Kristina Marie

    2002-01-01

    , 1997 to December 31, 1999 at Scott & White Memorial Hospital in Temple, TX were evaluated in a retrospective chart review. Malnutrition- and disease-matched patients who received oral nutrition support were selected from the hospital's patient database...

  16. The proper characteristics of frame reference as a 4-invariants

    E-Print Network [OSTI]

    V. V. Voytik

    2015-06-02

    The paper derived 4-dimensional equation for the proper characteristics of the rigid frame of reference. From these conditions it follows the laws of motion of its proper tetrad and inverse kinematics equation, i. e., differential equations, which solves the problem of recovering the parameters of the motion of rigid frame of reference for their proper acceleration and angular velocity. In particular it is shown that the commission boost the moving frame of reference having Thomas precession for a new laboratory system will have a combination of two rotations: a new self-Thomas precession and rotation Wigner, which combine to give an initial frequency of the Thomas precession.

  17. Phase I dose-escalation study of S-222611, an oral reversible dual tyrosine kinase inhibitor of EGFR and HER2, in patients with solid tumours

    E-Print Network [OSTI]

    Spicer, James; Baird, Richard; Suder, Aneta; Cresti, Nicola; Corbacho, Javier Garcia; Hogarth, Linda; Frenkel, Eugene; Matsumoto, Sayaka; Kawabata, Izumi; Donaldson, Kirsteen; Posner, John; Sarker, Debashis; Jodrell, Duncan; Plummer, Ruth

    2014-11-27

    of the EGFR/HER2 inhibitor S-222611 7/23 performed to estimate the PK parameters for S-222611 and metabolites based on plasma concentration (WinNonlin® Professional 5.2 or SAS® Version 9.2). The following PK parameters were estimated: maximum observed... tyrosine kinases, in heavily pretreated patients with metastatic carcinomas. J Clin Oncol 2005;23: 5305-13. Phase 1 study of the EGFR/HER2 inhibitor S-222611 16/23 6. Postel-Vinay S, Gomez-Roca, C., Molife, L.R., et al. Phase I trials of molecularly...

  18. Rapid Measurement of Neutron Dose Rate for Transport Index

    SciTech Connect (OSTI)

    Morris, R.L.

    2000-02-27

    A newly available neutron dose equivalent remmeter with improved sensitivity and energy response has been put into service at Rocky Flats Environmental Technology Site (RFETS). This instrument is being used to expedite measurement of the Transport Index and as an ALARA tool to identify locations where slightly elevated neutron dose equivalent rates exist. The meter is capable of measuring dose rates as low as 0.2 {mu}Sv per hour (20 {mu}rem per hour). Tests of the angular response and energy response of the instrument are reported. Calculations of the theoretical instrument response made using MCNP{trademark} are reported for materials typical of those being shipped.

  19. Peak Dose Assessment for Proposed DOE-PPPO Authorized Limits

    SciTech Connect (OSTI)

    Maldonado, Delis

    2012-06-01

    The Oak Ridge Institute for Science and Education (ORISE), a U.S. Department of Energy (DOE) prime contractor, was contracted by the DOE Portsmouth/Paducah Project Office (DOE-PPPO) to conduct a peak dose assessment in support of the Authorized Limits Request for Solid Waste Disposal at Landfill C-746-U at the Paducah Gaseous Diffusion Plant (DOE-PPPO 2011a). The peak doses were calculated based on the DOE-PPPO Proposed Single Radionuclides Soil Guidelines and the DOE-PPPO Proposed Authorized Limits (AL) Volumetric Concentrations available in DOE-PPPO 2011a. This work is provided as an appendix to the Dose Modeling Evaluations and Technical Support Document for the Authorized Limits Request for the C-746-U Landfill at the Paducah Gaseous Diffusion Plant, Paducah, Kentucky (ORISE 2012). The receptors evaluated in ORISE 2012 were selected by the DOE-PPPO for the additional peak dose evaluations. These receptors included a Landfill Worker, Trespasser, Resident Farmer (onsite), Resident Gardener, Recreational User, Outdoor Worker and an Offsite Resident Farmer. The RESRAD (Version 6.5) and RESRAD-OFFSITE (Version 2.5) computer codes were used for the peak dose assessments. Deterministic peak dose assessments were performed for all the receptors and a probabilistic dose assessment was performed only for the Offsite Resident Farmer at the request of the DOE-PPPO. In a deterministic analysis, a single input value results in a single output value. In other words, a deterministic analysis uses single parameter values for every variable in the code. By contrast, a probabilistic approach assigns parameter ranges to certain variables, and the code randomly selects the values for each variable from the parameter range each time it calculates the dose (NRC 2006). The receptor scenarios, computer codes and parameter input files were previously used in ORISE 2012. A few modifications were made to the parameter input files as appropriate for this effort. Some of these changes included increasing the time horizon beyond 1,050 years (yr), and using the radionuclide concentrations provided by the DOE-PPPO as inputs into the codes. The deterministic peak doses were evaluated within time horizons of 70 yr (for the Landfill Worker and Trespasser), 1,050 yr, 10,000 yr and 100,000 yr (for the Resident Farmer [onsite], Resident Gardener, Recreational User, Outdoor Worker and Offsite Resident Farmer) at the request of the DOE-PPPO. The time horizons of 10,000 yr and 100,000 yr were used at the request of the DOE-PPPO for informational purposes only. The probabilistic peak of the mean dose assessment was performed for the Offsite Resident Farmer using Technetium-99 (Tc-99) and a time horizon of 1,050 yr. The results of the deterministic analyses indicate that among all receptors and time horizons evaluated, the highest projected dose, 2,700 mrem/yr, occurred for the Resident Farmer (onsite) at 12,773 yr. The exposure pathways contributing to the peak dose are ingestion of plants, external gamma, and ingestion of milk, meat and soil. However, this receptor is considered an implausible receptor. The only receptors considered plausible are the Landfill Worker, Recreational User, Outdoor Worker and the Offsite Resident Farmer. The maximum projected dose among the plausible receptors is 220 mrem/yr for the Outdoor Worker and it occurs at 19,045 yr. The exposure pathways contributing to the dose for this receptor are external gamma and soil ingestion. The results of the probabilistic peak of the mean dose analysis for the Offsite Resident Farmer indicate that the average (arithmetic mean) of the peak of the mean doses for this receptor is 0.98 mrem/yr and it occurs at 1,050 yr. This dose corresponds to Tc-99 within the time horizon of 1,050 yr.

  20. Genetic Factors Affecting Susceptibility to Low Dose & Low Dose-Rate Radiation

    SciTech Connect (OSTI)

    Bedford, Joel

    2014-04-18

    Our laboratory has, among other things, developed and used the gamma H2AX focus assay and other chromosomal and cell killing assays to show that differences in this DNA double strand break (dsb) related response can be clearly and distinctly demonstrated for cells which are mildly hyper-radiosensitive such as those associated with A-T heterozygosity. We have found this level of mild hypersensitivity for cells from some 20 to 30 % of apparently normal individuals and from apparently normal parents of Retinoblastoma patients. We found significant differences in gene expression in somatic cells from unaffected parents of Rb patients as compared with normal controls, suggesting that these parents may harbor some as yet unidentified genetic abnormality. In other experiments we sought to determine the extent of differences in normal human cellular reaponses to radiation depending on their irradiation in 2D monolayer vs 3D organized acinar growth conditions. We exmined cell reproductive death, chromosomal aberration induction, and the levels of ?-H2AX foci in cells after single acute gamma-ray doses and immediately after 20 hours of irradiation at a dose rate of 0.0017 Gy/min. We found no significant differences in the dose-responses of these cells under the 2D or 3D growth conditions. While this does not mean such differences cannot occur in other situations, it does mean that they do not generally or necessarily occur. In another series of studies in collaboration with Dr Chuan Li, with supprt from this current grant. We reported a role for apoptotic cell death in promoting wound healing and tissue regeneration in mice. Apoptotic cells released growth signals that stimulated the proliferation of progenitor or stem cells. In yet another collaboration with Dr, B. Chen with funds from this grant, the relative radiosensitivity to cell killing as well as chromosomal instability of 13 DNA-PKcs site-directed mutant cell lines (defective at phosphorylation sites or kinase activity) were examined after exposure of synchronized G1 cells to 137Cs c rays. DNA-PKcs mutant cells defective in phosphorylation at multiple sites withinthe T2609 cluster or within the PI3K domain displayed extreme radiosensitivity. Cells defective at the S2056 cluster or T2609 single site alone were only mildly radiosensitive, but cells defective at even one site in both the S2056 and T2609 clusters were maximally radiosensitive. Thus a synergism between the capacity for phosphorylation at the S2056 and T2609 clusterswas found to be critical for induction of radiosensitivity.

  1. NBS SPEC. PUBL. 260 -16 Standard Reference Materials

    E-Print Network [OSTI]

    NBS SPEC. PUBL. 260 - 16 Standard Reference Materials: HOMOGENEITY CHARACTERIZATION OF NBS Materials: Homogeneity Characterization of NBS Spectrometric Standards IV: Preparation and Microprobe. L. Vieth Institute for Materials Research National Bureau of Standards Washington, D.C. 20234

  2. Library and Information Services Division Current References 2001-1

    E-Print Network [OSTI]

    1 Library and Information Services Division Current References 2001-1 Publications by National Library U. S. Department of Commerce National Oceanic and Atmospheric Administration National Environmental Satellite, Data, and Information Service National Oceanographic Data Center NOAA Central Library

  3. Motivation for the Transaction-Based Reference Platform

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Motivation for the Transaction-Based Reference Platform Or How I learned to Stop Worrying and Love Transactions George Hernandez Pacific Northwest National Lab July 23-24, 2015...

  4. Quantum geometrodynamical description of the Universe in different reference frames

    E-Print Network [OSTI]

    T. P. Shestakova

    2002-05-16

    Several years ago the so-called quantum geometrodynamics in extended phase space was proposed. The main role in this version of quantum geometrodynamics is given to a wave function that carries information about geometry of the Universe as well as about a reference frame in which this geometry is studied. We consider the evolution of a physical object (the Universe) in ``physical'' subspace of extended configurational space, the latter including gauge and ghost degrees of freedom. A measure of the ``physical'' subspace depends on a chosen reference frame, in particular, a small variation of a gauge-fixing function results in changing the measure. Thus, a transition to another gauge condition (another reference frame) leads to non-unitary transformation of a physical part of the wave function. From the viewpoint of the evolution of the Universe in the ``physical'' subspace a transition to another reference frame is an irreversible process that may be important when spacetime manifold has a nontrivial topology.

  5. Archive Reference Buildings by Building Type: Primary school

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the reference buildings for new construction commercial buildings, organized by building type and location. A summary of building types and climate zones is...

  6. Archive Reference Buildings by Building Type: Secondary school

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the reference buildings for new construction commercial buildings, organized by building type and location. A summary of building types and climate zones is...

  7. Bibliography of the Scripps Institution of Oceanography Reference Series 1996

    E-Print Network [OSTI]

    Jennings, Paige A.

    1997-01-01

    SCRIPPS INSTITUTION OF OCEANOGRAPHY REFERENCE SERIES Dufour,the Scripps Institution of Oceanography. January 1996. 42p.Scripps Institution of Oceanography. July 1996. 53p. 96-17

  8. Archive Reference Buildings by Building Type: Stand-alone retail

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the reference buildings for new construction commercial buildings, organized by building type and location. A summary of building types and climate zones is...

  9. Existing Commercial Reference Buildings Constructed Before 1980 — Archive

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the commercial reference building models for existing buildings constructed before 1980, organized by building type and location. A summary of building types and...

  10. X-ray Moiré deflectometry using synthetic reference images

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Stutman, Dan; Valdivia, Maria Pia; Finkenthal, Michael

    2015-06-25

    Moiré fringe deflectometry with grating interferometers is a technique that enables refraction-based x-ray imaging using a single exposure of an object. To obtain the refraction image, the method requires a reference fringe pattern (without the object). Our study shows that, in order to avoid artifacts, the reference pattern must be exactly matched in phase with the object fringe pattern. In experiments, however, it is difficult to produce a perfectly matched reference pattern due to unavoidable interferometer drifts. We present a simple method to obtain matched reference patterns using a phase-scan procedure to generate synthetic Moiré images. As a result, themore »method will enable deflectometric diagnostics of transient phenomena such as laser-produced plasmas and could improve the sensitivity and accuracy of medical phase-contrast imaging.« less

  11. Nuclear Science References Coding Manual D.F. Winchell

    E-Print Network [OSTI]

    Ohta, Shigemi

    Nuclear Science References Coding Manual D.F. Winchell National Nuclear Data Center Brookhaven and coding procedures for specific topics . . 18 3.2.1 NUCLEAR REACTIONS . . . . . . . . . . . . . . . . 19 3.2.2 RADIOACTIVITY . . . . . . . . . . . . . . . . . . . . 20 3.2.3 NUCLEAR STRUCTURE

  12. Archive Reference Buildings by Building Type: Fast food

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the reference buildings for new construction commercial buildings, organized by building type and location. A summary of building types and climate zones is...

  13. Archive Reference Buildings by Building Type: Small office

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the reference buildings for new construction commercial buildings, organized by building type and location. A summary of building types and climate zones is...

  14. Archive Reference Buildings by Building Type: Strip mall

    Broader source: Energy.gov [DOE]

    Here you will find past versions of the reference buildings for new construction commercial buildings, organized by building type and location. A summary of building types and climate zones is...

  15. Archive Reference Buildings by Building Type: Large office

    Office of Energy Efficiency and Renewable Energy (EERE)

    Here you will find past versions of the reference buildings for new construction commercial buildings, organized by building type and location. A summary of building types and climate zones is...

  16. Reference Buildings by Climate Zone and Representative City:...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Climate Zone and Representative City: 2B Phoenix, Arizona Reference Buildings by Climate Zone and Representative City: 2B Phoenix, Arizona In addition to the ZIP file for each...

  17. Library and Information Services Division Current References 2009-1

    E-Print Network [OSTI]

    Library and Information Services Division Current References 2009-1 The Year of Darwin 2009 Discovering Darwin at NOAA Central Library: Resources on Charles Darwin, Evolution, and the Galapagos Islands National Oceanographic Data Center NOAA Central Library October 2009 http

  18. Sage Quick Reference: Linear Algebra Robert A. Beezer

    E-Print Network [OSTI]

    Ehler, Martin

    Sage Quick Reference: Linear Algebra Robert A. Beezer Sage Version 4.8 http Combining Matrices A.augment(B) A in first columns, matrix B to the right A.stack(B) A in top rows, B below

  19. A comparative analysis of pupil attitudes toward selected oral language activities used with fifth graders in the public schools of Brazos County, Texas 

    E-Print Network [OSTI]

    Brusse, Frances Williams

    1967-01-01

    : Independent variables Hypotheses Importance of the Study Limitations of the Study Definition of Terms Used Attitudes toward oral language activities Selected oral language activities Oral language activity attitude scale White, Negro, and Latin... in school subjects, to be determined by school records of grades and of scores on standardized achievement tests. Definition of Terms Used Attitudes toward oral lan ua e activities. The individual's tendency to evaluate in a certain way the oral language...

  20. 'In vivo' Dose Measurements in High-Dose-Rate Brachytherapy Treatments for Cervical Cancer: A Project Proposal

    SciTech Connect (OSTI)

    Reynoso Mejia, C. A.; Buenfil Burgos, A. E.; Ruiz Trejo, C.; Mota Garcia, A.; Trejo Duran, E.; Rodriguez Ponce, M.; Gamboa de Buen, I.

    2010-12-07

    The aim of this thesis project is to compare doses calculated from the treatment planning system using computed tomography images, with those measured 'in vivo' by using thermoluminescent dosimeters placed at different regions of the rectum and bladder of a patient during high-dose-rate intracavitary brachytherapy treatment of uterine cervical carcinoma. The experimental dosimeters characterisation and calibration have concluded and the protocol to carry out the 'in vivo' measurements has been established. In this work, the calibration curves of two types of thermoluminescent dosimeters (rods and chips) are presented, and the proposed protocol to measure the 'in vivo' dose is fully described.

  1. Low dose ionizing radiation detection using conjugated polymers

    SciTech Connect (OSTI)

    Silva, E.A.B.; Borin, J.F.; Nicolucci, P.; Graeff, C.F.O.; Netto, T. Ghilardi; Bianchi, R.F.

    2005-03-28

    In this work, the effect of gamma radiation on the optical properties of poly[2-methoxy-5-(2{sup '}-ethylhexyloxy)-p-phenylenevinylene] (MEH-PPV) is studied. The samples were irradiated at room temperature with different doses from 0 Gy to 152 Gy using a {sup 60}Co gamma ray source. For thin films, significant changes in the UV-visible spectra were only observed at high doses (>1 kGy). In solution, shifts in absorption peaks are observed at low doses (<10 Gy), linearly dependent on dose. The shifts are explained by conjugation reduction, and possible causes are discussed. Our results indicate that MEH-PPV solution can be used as a dosimeter adequate for medical applications.

  2. Dose assessment for radioactive contamination of a child 

    E-Print Network [OSTI]

    Kowalczik, Jeffrey Aaron

    2009-05-15

    Dose assessments produced using the computer code MCNP are important to simulate events that are difficult to recreate experimentally. An emergency scenario involving whole-body skin contamination is one example of such an event. For these scenarios...

  3. Dose Rate Calculations for Rotary Mode Core Sampling Exhauster

    SciTech Connect (OSTI)

    FOUST, D.J.

    2000-10-26

    This document provides the calculated estimated dose rates for three external locations on the Rotary Mode Core Sampling (RMCS) exhauster HEPA filter housing, per the request of Characterization Field Engineering.

  4. Newton-Cartan Gravity in Noninertial Reference Frames

    E-Print Network [OSTI]

    Leo Rodriguez; James St. Germaine-Fuller; Sujeev Wickramasekara

    2014-12-26

    We study properties of Newton-Cartan gravity under transformations into all noninertial, nonrelativistic reference frames. The set of these transformations has the structure of an infinite dimensional Lie group, called the Galilean line group, which contains as a subgroup the Galilei group. We show that the fictitious forces of noninertial reference frames are naturally encoded in the Cartan connection transformed under the Galilean line group. These noninertial forces, which are coordinate effects, do not contribute to the Ricci tensor which describes the curvature of Newtonian spacetime. We show that only the $00$-component of the Ricci tensor is non-zero and equal to ($4\\pi$ times) the matter density in any inertial or noninetial reference frame and that it leads to what may be called Newtonian ADM mass. While the Ricci field equation and Gauss law are both fulfilled by the same physical matter density in inertial and linearly accelerating reference frames, there appears a discrepancy between the two in rotating reference frames in that Gauss law holds for an effective mass density that differs from the physical matter density. This effective density has its origin in the simulated magnetic field that appears in rotating frames, highlighting a rather striking difference between linearly and rotationally accelerating reference frames. We further show that the dynamical equations that govern the simulated gravitational and magnetic fields have the same form as Maxwell's equations, a surprising conclusion given that these equations are well-known to obey special relativity (and $U(1)$-gauge symmetry), rather than Galilean symmetry.

  5. GROUND-WATER CONTRIBUTION TO DOSE FROM PAST HANFORD OPERATIONS

    SciTech Connect (OSTI)

    Freshley, M. D.; Thorne, P. D.

    1992-01-01

    The Hanford Environmental Dose Reconstruction (HEOR) Project is being conducted to estimate radiation doses that populations and individuals could have received from Hanford Site operations from 1944 to the present. Four possible pathways by which radionuclides originating in ground water on the Hanford Site could have reached the public have been identified: 1) through contaminated ground water migrating to the Columbia River; 2) through wells on or adjacent to the Hanford Site; 3) through wells that draw some or all of their water from the Columbia River (riparian wells); and 4) through atmospheric deposition resulting in the contamination of a small watershed that, in turn, results in contamination of a shallow well or spring. These four pathways make up the "ground-water pathway ," which is the subject of this study. The objective of the study was to assess the extent to which the groundwater pathway contributed to radiation doses that populations or individuals may have received from past operations at Hanford. The assessment presented in this report was performed by 1) reviewing the extensive ?literature on ground water and ground-water monitoring at Hanford and 2) performing simple calculations to estimate radionuclide concentrations in ground water and the Columbia River resulting from ground-water discharge. Radiation doses that would result from exposure to this ground water and surface water were calculated. The study conclusion is that the ground-water pathways did not contribute significantly to dose. Compared with background radiation in the TriCities {300 mrem/yr), estimated doses are small: 0.02 mrem/yr effective dose equivalent from discharge of contaminated ground water to the Columbia River; 1 mrem/yr effective dose equivalent from Hanford Site wells; 11 mrem/yr effective dose equivalent from riparian wells; and 1 mrem/yr effective dose equivalent from the watershed. Because the estimated doses are so small, the recommendation is that further work on the ground-water pathway be limited to tracking ongoing ground-water studies at the Hanford Site.

  6. Emergency Doses (ED) - Revision 3: A calculator code for environmental dose computations

    SciTech Connect (OSTI)

    Rittmann, P.D.

    1990-12-01

    The calculator program ED (Emergency Doses) was developed from several HP-41CV calculator programs documented in the report Seven Health Physics Calculator Programs for the HP-41CV, RHO-HS-ST-5P (Rittman 1984). The program was developed to enable estimates of offsite impacts more rapidly and reliably than was possible with the software available for emergency response at that time. The ED - Revision 3, documented in this report, revises the inhalation dose model to match that of ICRP 30, and adds the simple estimates for air concentration downwind from a chemical release. In addition, the method for calculating the Pasquill dispersion parameters was revised to match the GENII code within the limitations of a hand-held calculator (e.g., plume rise and building wake effects are not included). The summary report generator for printed output, which had been present in the code from the original version, was eliminated in Revision 3 to make room for the dispersion model, the chemical release portion, and the methods of looping back to an input menu until there is no further no change. This program runs on the Hewlett-Packard programmable calculators known as the HP-41CV and the HP-41CX. The documentation for ED - Revision 3 includes a guide for users, sample problems, detailed verification tests and results, model descriptions, code description (with program listing), and independent peer review. This software is intended to be used by individuals with some training in the use of air transport models. There are some user inputs that require intelligent application of the model to the actual conditions of the accident. The results calculated using ED - Revision 3 are only correct to the extent allowed by the mathematical models. 9 refs., 36 tabs.

  7. Dose calculation for permanent prostate implants incorporating spatially anisotropic linearly time-resolving edema

    SciTech Connect (OSTI)

    Monajemi, T. T.; Clements, Charles M.; Sloboda, Ron S. [Department of Medical Physics, Cross Cancer Institute, Edmonton, Alberta T6G 1Z2 (Canada) and Department of Oncology, University of Alberta, Edmonton, Alberta T6G 2R3 (Canada); Department of Physics, University of Alberta, Edmonton, Alberta T6G 2R3 (Canada); Department of Medical Physics, Cross Cancer Institute, Edmonton, Alberta T6G 1Z2 (Canada); Department of Oncology, University of Alberta, Edmonton, Alberta T6G 2R3 (Canada) and Department of Physics, University of Alberta, Edmonton, Alberta T6G 2R3 (Canada)

    2011-04-15

    Purpose: The objectives of this study were (i) to develop a dose calculation method for permanent prostate implants that incorporates a clinically motivated model for edema and (ii) to illustrate the use of the method by calculating the preimplant dosimetry error for a reference configuration of {sup 125}I, {sup 103}Pd, and {sup 137}Cs seeds subject to edema-induced motions corresponding to a variety of model parameters. Methods: A model for spatially anisotropic edema that resolves linearly with time was developed based on serial magnetic resonance imaging measurements made previously at our center to characterize the edema for a group of n=40 prostate implant patients [R. S. Sloboda et al., ''Time course of prostatic edema post permanent seed implant determined by magnetic resonance imaging,'' Brachytherapy 9, 354-361 (2010)]. Model parameters consisted of edema magnitude, {Delta}, and period, T. The TG-43 dose calculation formalism for a point source was extended to incorporate the edema model, thus enabling calculation via numerical integration of the cumulative dose around an individual seed in the presence of edema. Using an even power piecewise-continuous polynomial representation for the radial dose function, the cumulative dose was also expressed in closed analytical form. Application of the method was illustrated by calculating the preimplant dosimetry error, RE{sub preplan}, in a 5x5x5 cm{sup 3} volume for {sup 125}I (Oncura 6711), {sup 103}Pd (Theragenics 200), and {sup 131}Cs (IsoRay CS-1) seeds arranged in the Radiological Physics Center test case 2 configuration for a range of edema relative magnitudes ({Delta}=[0.1,0.2,0.4,0.6,1.0]) and periods (T=[28,56,84] d). Results were compared to preimplant dosimetry errors calculated using a variation of the isotropic edema model developed by Chen et al. [''Dosimetric effects of edema in permanent prostate seed implants: A rigorous solution,'' Int. J. Radiat. Oncol., Biol., Phys. 47, 1405-1419 (2000)]. Results: As expected, RE{sub preplan} for our edema model indicated underdosage in the calculation volume with a clear dependence on seed and calculation point positions, and increased with increasing values of {Delta} and T. Values of RE{sub preplan} were generally larger near the ends of the virtual prostate in the RPC phantom compared with more central locations. For edema characteristics similar to the population average values previously measured at our center, i.e., {Delta}=0.2 and T=28 d, mean values of RE{sub preplan} in an axial plane located 1.5 cm from the center of the seed distribution were 8.3% for {sup 131}Cs seeds, 7.5% for {sup 103}Pd seeds, and 2.2% for {sup 125}I seeds. Maximum values of RE{sub preplan} in the same plane were about 1.5 times greater. Note that detailed results strictly apply only for loose seed implants where the seeds are fixed in tissue and move in synchrony with that tissue. Conclusions: A dose calculation method for permanent prostate implants incorporating spatially anisotropic linearly time-resolving edema was developed for which cumulative dose can be written in closed form. The method yields values for RE{sub preplan} that differ from those for spatially isotropic edema. The method is suitable for calculating pre- and postimplant dosimetry correction factors for clinical seed configurations when edema characteristics can be measured or estimated.

  8. Characterization of radiation beams used to determinate the correction factor for a CyberKnife® unit reference field using ionization chambers

    SciTech Connect (OSTI)

    Aragón-Martínez, Nestor Massillon-JL, Guerda; Gómez-Muñoz, Arnulfo

    2014-11-07

    This paper aimed to characterize a 6 MV x-ray beam from a Varian® iX linear accelerator in order to obtain the correction factors needed by the IAEA/AAPM new formalism{sup 1}. The experiments were performed in a liquid water phantom under different irradiation conditions: a) Calibration of the reference field of 10 cm × 10 cm at 90 cm SSD and 10 cm depth was carried out according to the TRS-398 protocol using three ionization chambers (IC) calibrated in different reference laboratory and b) Measurement of the absorbed dose rate at 70 cm SSD and 10 cm depth in a 10 cm × 10 cm and 5.4 cm × 5.4 cm fields was obtained in order to simulate the CyberKnife® conditions where maximum distance between the source and the detector is equal to 80 cm and the maximum field size is 6 cm diameter. Depending where the IC was calibrated, differences between 0.16% and 2.24% in the absorbed dose rate measured in the 10 cm × 10 cm field at 90 cm SSD were observed, while for the measurements at 70 cm SSD, differences between 1.27% and 3.88% were obtained. For the 5.4 cm × 5.4 cm field, the absorbed dose measured with the three ICs varies between 1.37% and 3.52%. The increase in the difference on the absorbed dose when decreasing the SSD could possibly be associated to scattering radiation generated from the collimators and/or the energy dependence of the ionization chambers to low-energy radiation. The results presented in this work suggest the importance of simulating the CyberKnife® conditions using other linear accelerator for obtaining the correction factors as proposed by the IAEA/AAPM new formalism in order to measure the absorbed dose with acceptable accuracy.

  9. Assessment of dedicated low-dose cardiac micro-CT reconstruction algorithms using the left ventricular volume of small rodents as a performance measure

    SciTech Connect (OSTI)

    Maier, Joscha; Sawall, Stefan; Kachelrieß, Marc

    2014-05-15

    Purpose: Phase-correlated microcomputed tomography (micro-CT) imaging plays an important role in the assessment of mouse models of cardiovascular diseases and the determination of functional parameters as the left ventricular volume. As the current gold standard, the phase-correlated Feldkamp reconstruction (PCF), shows poor performance in case of low dose scans, more sophisticated reconstruction algorithms have been proposed to enable low-dose imaging. In this study, the authors focus on the McKinnon-Bates (MKB) algorithm, the low dose phase-correlated (LDPC) reconstruction, and the high-dimensional total variation minimization reconstruction (HDTV) and investigate their potential to accurately determine the left ventricular volume at different dose levels from 50 to 500 mGy. The results were verified in phantom studies of a five-dimensional (5D) mathematical mouse phantom. Methods: Micro-CT data of eight mice, each administered with an x-ray dose of 500 mGy, were acquired, retrospectively gated for cardiac and respiratory motion and reconstructed using PCF, MKB, LDPC, and HDTV. Dose levels down to 50 mGy were simulated by using only a fraction of the projections. Contrast-to-noise ratio (CNR) was evaluated as a measure of image quality. Left ventricular volume was determined using different segmentation algorithms (Otsu, level sets, region growing). Forward projections of the 5D mouse phantom were performed to simulate a micro-CT scan. The simulated data were processed the same way as the real mouse data sets. Results: Compared to the conventional PCF reconstruction, the MKB, LDPC, and HDTV algorithm yield images of increased quality in terms of CNR. While the MKB reconstruction only provides small improvements, a significant increase of the CNR is observed in LDPC and HDTV reconstructions. The phantom studies demonstrate that left ventricular volumes can be determined accurately at 500 mGy. For lower dose levels which were simulated for real mouse data sets, the HDTV algorithm shows the best performance. At 50 mGy, the deviation from the reference obtained at 500 mGy were less than 4%. Also the LDPC algorithm provides reasonable results with deviation less than 10% at 50 mGy while PCF and MKB reconstruction show larger deviations even at higher dose levels. Conclusions: LDPC and HDTV increase CNR and allow for quantitative evaluations even at dose levels as low as 50 mGy. The left ventricular volumes exemplarily illustrate that cardiac parameters can be accurately estimated at lowest dose levels if sophisticated algorithms are used. This allows to reduce dose by a factor of 10 compared to today's gold standard and opens new options for longitudinal studies of the heart.

  10. Electrical activation and spin coherence of ultra low dose antimony implants in silicon

    E-Print Network [OSTI]

    2005-01-01

    and spin coherence of ultra low dose antimony implants inClara, CA 95054 We implanted ultra low doses (0.2 to 2×10 11100 nm, corresponding to ultra low ion implantation doses of

  11. The Long and Winding Road to Building an Electronic Reference Collection

    E-Print Network [OSTI]

    Morris, Sara E.; Devlin, Frances A.

    2011-10-18

    The Starting Line • Subscriptions to aggregated reference collections – Examples: CREDO Reference, Oxford Reference Online, Gale Virtual Reference Library The Starting Line • Subscription reference titles, not sold as books – Chicago Manual of Style... – Reference E-Books • No usage! • Staff didn’t remember Record with 655 added LibGuide Proceed with Caution… • Solution – Catalog tab • “Electronic Reference Works” – Focusing on four publishers • Credo, Oxford, Sage, Gale – Getting titles...

  12. References R-3 ANS 1986. Glossary of Terms in Nuclear Science and Technology, American Nuclear Society.

    E-Print Network [OSTI]

    Pennycook, Steve

    of Energy, Washington, D.C.. DOE 1988b. Internal Dose Conversion Factors for Calculation of Dose, Tennessee, DOE/OR/01-1623&D1, U.S. Department of Energy, Washington, D.C. DOE 1998a. Engineering Evaluation/Cost. External Dose-Rate Conversion Factors for Calculation of Dose to the Public, DOE/EH-0070, U.S. Department

  13. INTEGRATED CODES FOR ESTIMATING ENVIRONMENTAL ACCUMULATION ANd INDIVIDUAL DOSE FROM PAST HANFORD ATMOSPHERIC RELEASES Hanford Environmental Dose Reconstruction Project

    SciTech Connect (OSTI)

    Ikenberry, T. A.; Burnett, R. A.; Napier, B. A.; Reitz, N. A.; Shipler, D. B.

    1992-02-01

    Preliminary radiation doses were estimated and reported during Phase I of the Hanford Environmental Dose Reconstruction (HEDR) Project. As the project has progressed, additional information regarding the magnitude and timing of past radioactive releases has been developed, and the general scope of the required calculations has been enhanced. The overall HEDR computational model for computing doses attributable to atmospheric releases from Hanford Site operations is called HEDRIC (Hanford Environmental Dose Reconstruction Integrated Codes). It consists of four interrelated models: source term, atmospheric transport, environmental accumulation, and individual dose. The source term and atmospheric transport models are documented elsewhere. This report describes the initial implementation of the design specifications for the environmental accumulation model and computer code, called DESCARTES (Dynamic EStimates of Concentrations and Accumulated Radionuclides in Terrestrial Environments), and the individual dose model and computer code, called CIDER (Calculation of Individual Doses from Environmental Radionuclides). The computations required of these models and the design specifications for their codes were documented in Napier et al. (1992). Revisions to the original specifications and the basis for modeling decisions are explained. This report is not the final code documentation but gives the status of the model and code development to date. Final code documentation is scheduled to be completed in FY 1994 following additional code upgrades and refinements. The user's guide included in this report describes the operation of the environmental accumulation and individual dose codes and associated pre- and post-processor programs. A programmer's guide describes the logical structure of the programs and their input and output files.

  14. Mechanisms of Low Dose Radio-Suppression of Genomic Instability

    SciTech Connect (OSTI)

    Engelward, Bevin P

    2009-09-16

    The major goal of this project is to contribute toward the elucidation of the impact of long term low dose radiation on genomic stability. We have created and characterized novel technologies for delivering long term low dose radiation to animals, and we have studied genomic stability by applying cutting edge molecular analysis technologies. Remarkably, we have found that a dose rate that is 300X higher than background radiation does not lead to any detectable genomic damage, nor is there any significant change in gene expression for genes pertinent to the DNA damage response. These results point to the critical importance of dose rate, rather than just total dose, when evaluating public health risks and when creating regulatory guidelines. In addition to these studies, we have also further developed a mouse model for quantifying cells that have undergone a large scale DNA sequence rearrangement via homologous recombination, and we have applied these mice in studies of both low dose radiation and space radiation. In addition to more traditional approaches for assessing genomic stability, we have also explored radiation and possible beneficial effects (adaptive response), long term effects (persistent effects) and effects on communication among cells (bystander effects), both in vitro and in vivo. In terms of the adaptive response, we have not observed any significant induction of an adaptive response following long term low dose radiation in vivo, delivered at 300X background. In terms of persistent and bystander effects, we have revealed evidence of a bystander effect in vivo and with researchers at and demonstrated for the first time the molecular mechanism by which cells “remember” radiation exposure. Understanding the underlying molecular mechanisms by which radiation can induce genomic instability is fundamental to our ability to assess the biological impact of low dose radiation. Finally, in a parallel set of studies we have explored the effects of heavy iron particle radiation on large scale sequence rearrangements and we have discovered tissue specific differences in sensitivity to homologous recombination. DOE support has given rise to critical new knowledge about the biological impact of low dose rate radiation and about the underlying mechanisms that govern genomic stability in response to radiation exposure. This work has spurred interest in radiation among MIT scientists, and has fostered ongoing research projects that will continue to contribute toward our understanding of the biological effects of low dose radiation exposure.

  15. Dose optimization in cardiac x-ray imaging

    SciTech Connect (OSTI)

    Gislason-Lee, Amber J.; McMillan, Catherine; Cowen, Arnold R.; Davies, Andrew G.

    2013-09-15

    Purpose: The aim of this research was to optimize x-ray image quality to dose ratios in the cardiac catheterization laboratory. This study examined independently the effects of peak x-ray tube voltage (kVp), copper (Cu), and gadolinium (Gd) x-ray beam filtration on the image quality to radiation dose balance for adult patient sizes.Methods: Image sequences of polymethyl methacrylate (PMMA) phantoms representing two adult patient sizes were captured using a modern flat panel detector based x-ray imaging system. Tin and copper test details were used to simulate iodine-based contrast medium and stents/guide wires respectively, which are used in clinical procedures. Noise measurement for a flat field image and test detail contrast were used to calculate the contrast to noise ratio (CNR). Entrance surface dose (ESD) and effective dose measurements were obtained to calculate the figure of merit (FOM), CNR{sup 2}/dose. This FOM determined the dose efficiency of x-ray spectra investigated. Images were captured with 0.0, 0.1, 0.25, 0.4, and 0.9 mm Cu filtration and with a range of gadolinium oxysulphide (Gd{sub 2}O{sub 2}S) filtration.Results: Optimum x-ray spectra were the same for the tin and copper test details. Lower peak tube voltages were generally favored. For the 20 cm phantom, using 2 Lanex Fast Back Gd{sub 2}O{sub 2}S screens as x-ray filtration at 65 kVp provided the highest FOM considering ESD and effective dose. Considering ESD, this FOM was only marginally larger than that from using 0.4 mm Cu at 65 kVp. For the 30 cm phantom, using 0.25 mm copper filtration at 80 kVp was most optimal; considering effective dose the FOM was highest with no filtration at 65 kVp.Conclusions: These settings, adjusted for x-ray tube loading limits and clinically acceptable image quality, should provide a useful option for optimizing patient dose to image quality in cardiac x-ray imaging. The same optimal x-ray beam spectra were found for both the tin and copper details, suggesting that iodine contrast based imaging and visualization of interventional devices could potentially be optimized for dose using similar x-ray beam spectra.

  16. References R-3 Note: In this report we refer to a number of documents (e.g., plans, reports) that are intended for internal

    E-Print Network [OSTI]

    Pennycook, Steve

    References #12;#12;References R-3 References Note: In this report we refer to a number of documents function as a means of communication between governmental agencies and the tenant companies on the Oak, Appendix B: WAG 1 Groundwater, Surface Water, and Sediment. DOE/OR-1043/V4&D1. U.S. Department of Energy

  17. SU-E-J-229: Quantitative Assessment for Timely Adaptive Re-Planning Using Weekly Dose Monitoring for Head and Neck Cancer

    SciTech Connect (OSTI)

    Shang, Q; Liu, H; Greskovich, J; Koyfman, S; Xia, P; Li, Z

    2014-06-01

    Purpose: For patients with head and neck (HN) cancer, mid-course adaptive radiation therapy (ART) is a common practice in our institution to accommodate anatomic changes. The aim of the study is to evaluate whether dose re-calculation on weekly verification images can provide quantitative assessment for timely adaptive re-planning with daily image-guided intensity modulated radiotherapy (IMRT). Methods: We retrospectively selected sixty daily verification images acquired on CT-on-rail/CBCT from ten HN patients. These image sets were typically a week apart. Among these patients, six patients received a mid-course ART. Contours of the tumors and organ-at-risks (OARs) were manually delineated by a physician on each verification CT. After placing the treatment iso-center on the verification CTs according to the recorded clinical shifts, daily dose was re-calculated with the same beam configuration as the original plan. For the purpose of this study, electron densities for both verification CTs and planning CTs were set to 1.0 g/cm3. Results: Two patients had D99 of the CTV < 97% of the planned dose for more than three fractions due to remarkable tumor volume shrinkages. D-max of the spinal cord exceeded a tolerance of 45 Gy for four fractions in additional two patients. D-mean of the parotid increased within 25% of the planned value. D-max of the brainstem and D-mean of the oral cavity did not show significant variation. If the re-planning criteria included D99 of the CTV < 97% of the planned dose and D-max of the spinal cord > 45 Gy, two out ten patients required ART at week 2 and two patients required ART at week 3, respectively. Conclusion: Weekly dose monitoring with re-calculation on verification images can provide quantitative dose guidance for timely adaptive re-planning. Future work will include accumulative dose analysis for the decision of adaptive re-planning. The study is supported in part by Siemens Medical Solutions.

  18. Low-Dose Radiation Cataract and Genetic Determinants of Radiosensitivity

    SciTech Connect (OSTI)

    Kleiman, Norman Jay

    2013-11-30

    The lens of the eye is one of the most radiosensitive tissues in the body. Ocular ionizing radiation exposure results in characteristic, dose related, progressive lens changes leading to cataract formation. While initial, early stages of lens opacification may not cause visual disability, the severity of such changes progressively increases with dose until vision is impaired and cataract extraction surgery may be required. Because of the transparency of the eye, radiation induced lens changes can easily be followed non-invasively over time. Thus, the lens provides a unique model system in which to study the effects of low dose ionizing radiation exposure in a complex, highly organized tissue. Despite this observation, considerable uncertainties remain surrounding the relationship between dose and risk of developing radiation cataract. For example, a growing number of human epidemiological findings suggest significant risk among various groups of occupationally and accidentally exposed individuals and confidence intervals that include zero dose. Nevertheless, questions remain concerning the relationship between lens opacities, visual disability, clinical cataract, threshold dose and/or the role of genetics in determining radiosensitivity. Experimentally, the response of the rodent eye to radiation is quite similar to that in humans and thus animal studies are well suited to examine the relationship between radiation exposure, genetic determinants of radiosensitivity and cataractogenesis. The current work has expanded our knowledge of the low-dose effects of X-irradiation or high-LET heavy ion exposure on timing and progression of radiation cataract and has provided new information on the genetic, molecular, biochemical and cell biological features which contribute to this pathology. Furthermore, findings have indicated that single and/or multiple haploinsufficiency for various genes involved in DNA repair and cell cycle checkpoint control, such as Atm, Brca1 or Rad9, influence cataract development and thus radiosensitivity. These observations have direct applicability to various human populations including accidentally exposed individuals, interventional medical workers, astronauts and nuclear plant workers.

  19. Does administering iodine in radiological procedures increase patient doses?

    SciTech Connect (OSTI)

    He, Wenjun; Yao, Hai, E-mail: haiyao@clemson.edu [Clemson-MUSC Bioengineering Program, Department of Bioengineering, Clemson University, Charleston, South Carolina 29425 (United States); Huda, Walter; Mah, Eugene [Department of Radiology and Radiological Science, Medical University of South Carolina (MUSC), Charleston, South Carolina 29425 (United States)

    2014-11-01

    Purpose: The authors investigated the changes in the pattern of energy deposition in tissue equivalent phantoms following the introduction of iodinated contrast media. Methods: The phantom consisted of a small “contrast sphere,” filled with water or iodinated contrast, located at the center of a 28 cm diameter water sphere. Monte Carlo simulations were performed using MCNP5 codes, validated by simulating irradiations with analytical solutions. Monoenergetic x-rays ranging from 35 to 150 keV were used to simulate exposures to spheres containing contrast agent with iodine concentrations ranging from 1 to 100 mg/ml. Relative values of energy imparted to the contrast sphere, as well as to the whole phantom, were calculated. Changes in patterns of energy deposition around the contrast sphere were also investigated. Results: Small contrast spheres can increase local absorbed dose by a factor of 13, but the corresponding increase in total energy absorbed was negligible (<1%). The highest localized dose increases were found to occur at incident photon energies of about 60 keV. For a concentration of about 10 mg/ml, typical of clinical practice, localized absorbed doses were generally increased by about a factor of two. At this concentration of 10 mg/ml, the maximum increase in total energy deposition in the phantom was only 6%. These simulations demonstrated that increases in contrast sphere doses were offset by corresponding dose reductions at distal and posterior locations. Conclusions: Adding iodine can result in values of localized absorbed dose increasing by more than an order of magnitude, but the total energy deposition is generally very modest (i.e., <10%). Their data show that adding iodine primarily changes the pattern of energy deposition in the irradiated region, rather than increasing patient doses per se.

  20. REFERENCE CASES FOR USE IN THE CEMENTITOUS PARTNERSHIP PROJECT

    SciTech Connect (OSTI)

    Langton, C.; Kosson, D.; Garrabrants, A.

    2010-08-31

    The Cementitious Barriers Partnership Project (CBP) is a multi-disciplinary, multi-institution cross cutting collaborative effort supported by the US Department of Energy (DOE) to develop a reasonable and credible set of tools to improve understanding and prediction of the structural, hydraulic and chemical performance of cementitious barriers used in nuclear applications. The period of performance is >100 years for operating facilities and > 1000 years for waste management. The CBP has defined a set of reference cases to provide the following functions: (i) a common set of system configurations to illustrate the methods and tools developed by the CBP, (ii) a common basis for evaluating methodology for uncertainty characterization, (iii) a common set of cases to develop a complete set of parameter and changes in parameters as a function of time and changing conditions, (iv) a basis for experiments and model validation, and (v) a basis for improving conceptual models and reducing model uncertainties. These reference cases include the following two reference disposal units and a reference storage unit: (i) a cementitious low activity waste form in a reinforced concrete disposal vault, (ii) a concrete vault containing a steel high-level waste tank filled with grout (closed high-level waste tank), and (iii) a spent nuclear fuel basin during operation. Each case provides a different set of desired performance characteristics and interfaces between materials and with the environment. Examples of concretes, grout fills and a cementitious waste form are identified for the relevant reference case configurations.

  1. Feasibility study of a dual detector configuration concept for simultaneous megavoltage imaging and dose verification in radiotherapy

    SciTech Connect (OSTI)

    Deshpande, Shrikant; McNamara, Aimee L.; Holloway, Lois; Metcalfe, Peter; Vial, Philip

    2015-04-15

    Purpose: To test the feasibility of a dual detector concept for comprehensive verification of external beam radiotherapy. Specifically, the authors test the hypothesis that a portal imaging device coupled to a 2D dosimeter provides a system capable of simultaneous imaging and dose verification, and that the presence of each device does not significantly detract from the performance of the other. Methods: The dual detector configuration comprised of a standard radiotherapy electronic portal imaging device (EPID) positioned directly on top of an ionization-chamber array (ICA) with 2 cm solid water buildup material (between EPID and ICA) and 5 cm solid backscatter material. The dose response characteristics of the ICA and the imaging performance of the EPID in the dual detector configuration were compared to the performance in their respective reference clinical configurations. The reference clinical configurations were 6 cm solid water buildup material, an ICA, and 5 cm solid water backscatter material as the reference dosimetry configuration, and an EPID with no additional buildup or solid backscatter material as the reference imaging configuration. The dose response of the ICA was evaluated by measuring the detector’s response with respect to off-axis position, field size, and transit object thickness. Clinical dosimetry performance was evaluated by measuring a range of clinical intensity-modulated radiation therapy (IMRT) beams in transit and nontransit geometries. The imaging performance of the EPID was evaluated quantitatively by measuring the contrast-to-noise ratio (CNR) and spatial resolution. Images of an anthropomorphic phantom were also used for qualitative assessment. Results: The measured off-axis and field size response with the ICA in both transit and nontransit geometries for both dual detector configuration and reference dosimetry configuration agreed to within 1%. Transit dose response as a function of object thickness agreed to within 0.5%. All IMRT test patterns and clinical IMRT beams had gamma pass rates of ?98% at 2%/2 mm criteria. In terms of imaging performance, the measured CNR and spatial resolution (f{sub 50}) were 263.23 ± 24.85 and 0.4025 ± 1.25 × 10{sup ?3} for dual detector configuration and 324 ± 26.65 and 0.4141 ± 1.14 × 10{sup ?3} for reference imaging configuration, respectively. The CNR and spatial resolution were quantitatively worse in the dual detector configuration due to the additional backscatter. The difference in imaging performance was not visible in qualitative assessment of phantom images. Conclusions: Combining a commercially available ICA dosimetry device with a conventional EPID did not significantly detract from the performance of either device. Further improvements in imaging performance may be achieved with an optimized design. This study demonstrates the feasibility of a dual detector concept for simultaneous imaging and dosimetry in radiation therapy.

  2. Technology, Safety and Costs of Decommissioning a Reference Uranium Hexafluoride Conversion Plant

    SciTech Connect (OSTI)

    Elder, H. K.

    1981-10-01

    Safety and cost information is developed for the conceptual decommissioning of a commercial uranium hexafluoride conversion (UF{sub 6}) plant. Two basic decommissioning alternatives are studied to obtain comparisons between cost and safety impacts: DECON, and passive SAFSTOR. A third alternative, DECON of the plant and equipment with stabilization and long-term care of lagoon wastes. is also examined. DECON includes the immediate removal (following plant shutdown) of all radioactivity in excess of unrestricted release levels, with subsequent release of the site for public use. Passive SAFSTOR requires decontamination, preparation, maintenance, and surveillance for a period of time after shutdown, followed by deferred decontamination and unrestricted release. DECON with stabilization and long-term care of lagoon wastes (process wastes generated at the reference plant and stored onsite during plant operation} is also considered as a decommissioning method, although its acceptability has not yet been determined by the NRC. The decommissioning methods assumed for use in each decommissioning alternative are based on state-of-the-art technology. The elapsed time following plant shutdown required to perform the decommissioning work in each alternative is estimated to be: for DECON, 8 months; for passive SAFSTOR, 3 months to prepare the plant for safe storage and 8 months to accomplish deferred decontamination. Planning and preparation for decommissioning prior to plant shutdown is estimated to require about 6 months for either DECON or passive SAFSTOR. Planning and preparation prior to starting deferred decontamination is estimated to require an additional 6 months. OECON with lagoon waste stabilization is estimated to take 6 months for planning and about 8 months to perform the decommissioning work. Decommissioning cost, in 1981 dollars, is estimated to be $5.91 million for OECON. For passive SAFSTOR, preparing the facility for safe storage is estimated to cost $0.88 million, the annual maintenance and surveillance cost is estimated to be about $0.095 million, and deferred decontamination is estimated to cost about $6.50 million. Therefore, passive SAFSTOR for 10 years is estimated to cost $8.33 million in nondiscounted 1981 dollars. DECON with lagoon waste stabilization is estimated to cost about $4.59 million, with an annual cost of $0.011 million for long-term care. All of these estimates include a 25% contingency. Waste management costs for DECON, including the net cost of disposal of the solvent extraction lagoon wastes by shipping those wastes to a uranium mill for recovery of residual uranium, comprise about 38% of the total decommissioning cost. Disposal of lagoon waste at a commercial low-level waste burial ground is estimated to add $10.01 million to decommissioning costs. Safety analyses indicate that radiological and nonradiological safety impacts from decommissioning activities should be small. The 50-year committed dose equivalent to members of the public from airborne releases during normal decommissioning activities is estimated to 'Je about 4.0 man-rem. Radiation doses to the public from accidents are found to be very low for all phases of decommissioning. Occupational radiation doses from normal decommissioning operations (excluding transport operations) are estimated to be about 79 man-rem for DECON and about 80 man-rem for passive SAFSTOR with 10 years of safe storage. Doses from DECON with lagoon waste stabilization are about the same as for DECON except there is less dose resulting from transportation of radioactive waste. The number of fatalities and serious lost-time injuries not related to radiation is found to be very small for all decommissioning alternatives. Comparison of the cost estimates shows that DECON with lagoon waste stabilization is the least expensive method. However, this alternative does not allow unrestricted release of the site. The cumulative cost of maintenance and surveillance and the higher cost of deferred decontamination makes passive SAFSTOR more expensive than DECON. Seve

  3. SU-D-16A-01: A Novel Method to Estimate Normal Tissue Dose for Radiotherapy Patients to Support Epidemiologic Studies of Second Cancer Risk

    SciTech Connect (OSTI)

    Lee, C; Jung, J; Pelletier, C; Kim, J; Lee, C

    2014-06-01

    Purpose: Patient cohort of second cancer study often involves radiotherapy patients with no radiological images available: We developed methods to construct a realistic surrogate anatomy by using computational human phantoms. We tested this phantom images both in a commercial treatment planning system (Eclipse) and a custom Monte Carlo (MC) transport code. Methods: We used a reference adult male phantom defined by International Commission on Radiological Protection (ICRP). The hybrid phantom which was originally developed in Non-Uniform Rational B-Spline (NURBS) and polygon mesh format was converted into more common medical imaging format. Electron density was calculated from the material composition of the organs and tissues and then converted into DICOM format. The DICOM images were imported into the Eclipse system for treatment planning, and then the resulting DICOM-RT files were imported into the MC code for MC-based dose calculation. Normal tissue doses were calculation in Eclipse and MC code for an illustrative prostate treatment case and compared to each other. Results: DICOM images were generated from the adult male reference phantom. Densities and volumes of selected organs between the original phantom and ones represented within Eclipse showed good agreements, less than 0.6%. Mean dose from Eclipse and MC code match less than 7%, whereas maximum and minimum doses were different up to 45%. Conclusion: The methods established in this study will be useful for the reconstruction of organ dose to support epidemiological studies of second cancer in cancer survivors treated by radiotherapy. We also work on implementing body size-dependent computational phantoms to better represent patient's anatomy when the height and weight of patients are available.

  4. Using Pin as a Memory Reference Generator for Multiprocessor Simulation

    SciTech Connect (OSTI)

    McCurdy, C

    2005-10-22

    In this paper we describe how we have used Pin to generate a multithreaded reference stream for simulation of a multiprocessor on a uniprocessor. We have taken special care to model as accurately as possible the effects of cache coherence protocol state, and lock and barrier synchronization on the performance of multithreaded applications running on multiprocessor hardware. We first describe a simplified version of the algorithm, which uses semaphores to synchronize instrumented application threads and the simulator on every memory reference. We then describe modifications to that algorithm to model the microarchitectural features of the Itanium2 that affect the timing of memory reference issue. An experimental evaluation determines that while cycle-accurate multithreaded simulation is possible using our approach, the use of semaphores has a negative impact on the performance of the simulator.

  5. PRECEDENTS FOR AUTHORIZATION OF CONTENTS USING DOSE RATE MEASUREMENTS

    SciTech Connect (OSTI)

    Abramczyk, G.; Bellamy, S.; Nathan, S.; Loftin, B.

    2012-06-05

    For the transportation of Radioactive Material (RAM) packages, the requirements for the maximum allowed dose rate at the package surface and in its vicinity are given in Title 10 of the Code of Federal Regulations, Section 71.47. The regulations are based on the acceptable dose rates to which the public, workers, and the environment may be exposed. As such, the regulations specify dose rates, rather than quantity of radioactive isotopes and require monitoring to confirm the requirements are met. 10CFR71.47 requires that each package of radioactive materials offered for transportation must be designed and prepared for shipment so that under conditions normally incident to transportation the radiation level does not exceed 2 mSv/h (200 mrem/h) at any point on the external Surface of the package, and the transport index does not exceed 10. Before shipment, the dose rate of the package is determined by measurement, ensuring that it conforms to the regulatory limits, regardless of any analyses. This is the requirement for all certified packagings. This paper discusses the requirements for establishing the dose rates when shipping RAM packages and the precedents for meeting these requirements by measurement.

  6. The Reference Design for the ILC, Costs, and What's Next

    SciTech Connect (OSTI)

    Barish, Barry

    2007-03-26

    A Reference Design for the International Linear Collider was recently released. The scale of the ILC is such that it must be built by an international collaboration and the design is the culmination of a unique global effort. Through ICFA, a decision was made to base the design on superconducting RF technology and then the Global Design Effort (GDE) was created to coordinate the actual accelerator design toward a construction proposal. The reference design establishes all the features of the machine, and defines both the R&D program and engineering design that will now follow over the next few years.

  7. Calculation of intervention doses for the CNGS facility

    E-Print Network [OSTI]

    Lorenzo-Sentis, M; Roesler, Stefan

    2006-01-01

    The purpose of the CNGS (CERN Neutrinos to Gran Sasso) project is to generate at CERN a powerful artificial muon-neutrino beam aimed at the Gran Sasso Laboratory in Italy. There, detectors will detect those neutrinos and try to disentangle those, which on their 730 km trip have changed their flavour. During the operating lifetime of the neutrino beam facility some interventions are required. These maintenance operations have to be planned in advance to define the guidelines of design and operational procedures in order to keep the doses received by personnel As Low As Reasonably Achievable (ALARA-principle). A calculational method developed for the Monte Carlo simulation program FLUKA has been used, which allows one to compute dose equivalent rates from induced radioactivity for different cooling times in the regions of the human intervention. In this paper the method of calculation is described, the results of dose equivalent rate in the areas of interventions are summarized and discussed and finally, these ...

  8. Estimation of food consumption. Hanford Environmental Dose Reconstruction Project

    SciTech Connect (OSTI)

    Callaway, J.M. Jr.

    1992-04-01

    The research reported in this document was conducted as a part of the Hanford Environmental Dose Reconstruction (HEDR) Project. The objective of the HEDR Project is to estimate the radiation doses that people could have received from operations at the Hanford Site. Information required to estimate these doses includes estimates of the amounts of potentially contaminated foods that individuals in the region consumed during the study period. In that general framework, the objective of the Food Consumption Task was to develop a capability to provide information about the parameters of the distribution(s) of daily food consumption for representative groups in the population for selected years during the study period. This report describes the methods and data used to estimate food consumption and presents the results developed for Phase I of the HEDR Project.

  9. Mean glandular dose in a breast screening programme

    SciTech Connect (OSTI)

    Galvan, H. A.; Perez-Badillo, M. P.; Villasenor, Y.

    2012-10-23

    Breast density has an important role in early detection of breast cancer, because has been reported the strong association between breast density and invasive breast cancer risk. Mammography is the gold standard to early detection of breast cancer, despite of this require ionizing radiation that may increase radio-induced cancer risk. This maybe limited with a quality control programme of mammographic units, with the main goal of achieving high quality images with low radiation dose. International Atomic Energy Agency (IAEA) published in 2011 the {sup Q}uality assurance programme for digital mammography{sup ,} where glandular tissue quantity is an important parameter to compute mean glandular dose (MGD), which is necessary to reduce its associated risk. In this work we show the first results in our country applying this protocol and studying breast density in a small group. MGD complies with national and IAEA dose limits.

  10. Severe 20-nail psoriasis successfully treated by low dose methotrexate

    E-Print Network [OSTI]

    Lee, Julia Yu-Yun

    2009-01-01

    A, Forleo P, et al. Nail psoriasis; comined therapy withReferences 1. Zaias N. Psoriasis of the nail: A clinicalPubMed ] 2. Scher RK. Psoriasis of the nail. Dermatol Clin

  11. HDRMC, an accelerated Monte Carlo dose calculator for high dose rate brachytherapy with CT-compatible applicators

    SciTech Connect (OSTI)

    Chibani, Omar C-M Ma, Charlie

    2014-05-15

    Purpose: To present a new accelerated Monte Carlo code for CT-based dose calculations in high dose rate (HDR) brachytherapy. The new code (HDRMC) accounts for both tissue and nontissue heterogeneities (applicator and contrast medium). Methods: HDRMC uses a fast ray-tracing technique and detailed physics algorithms to transport photons through a 3D mesh of voxels representing the patient anatomy with applicator and contrast medium included. A precalculated phase space file for the{sup 192}Ir source is used as source term. HDRM is calibrated to calculated absolute dose for real plans. A postprocessing technique is used to include the exact density and composition of nontissue heterogeneities in the 3D phantom. Dwell positions and angular orientations of the source are reconstructed using data from the treatment planning system (TPS). Structure contours are also imported from the TPS to recalculate dose-volume histograms. Results: HDRMC was first benchmarked against the MCNP5 code for a single source in homogenous water and for a loaded gynecologic applicator in water. The accuracy of the voxel-based applicator model used in HDRMC was also verified by comparing 3D dose distributions and dose-volume parameters obtained using 1-mm{sup 3} versus 2-mm{sup 3} phantom resolutions. HDRMC can calculate the 3D dose distribution for a typical HDR cervix case with 2-mm resolution in 5 min on a single CPU. Examples of heterogeneity effects for two clinical cases (cervix and esophagus) were demonstrated using HDRMC. The neglect of tissue heterogeneity for the esophageal case leads to the overestimate of CTV D90, CTV D100, and spinal cord maximum dose by 3.2%, 3.9%, and 3.6%, respectively. Conclusions: A fast Monte Carlo code for CT-based dose calculations which does not require a prebuilt applicator model is developed for those HDR brachytherapy treatments that use CT-compatible applicators. Tissue and nontissue heterogeneities should be taken into account in modern HDR brachytherapy planning.

  12. Dosimetry for quantitative analysis of the effects of low-dose ionizing radiation in radiation therapy patients

    E-Print Network [OSTI]

    2006-01-01

    for studying low- dose radiation at the doses discussed hereof the Effects of Low-Dose Ionizing Radiation in Radiationof the Effects of Low-Dose Ionizing Radiation in Ra- diation

  13. Phase 1 of the Hanford Environmental Dose Reconstruction Project

    SciTech Connect (OSTI)

    Not Available

    1990-07-20

    For more than 40 years, the US government made plutonium for nuclear weapons at the Hanford Site in southeastern Washington State. Radioactive materials were released to both the air and water from Hanford. People could have been exposed to these materials, called radionuclides. The Hanford Environmental Dose Reconstruction (HEDR) Project is a multi-year scientific study to estimate the radiation doses the public may have received as a results of these releases. The study began in 1988. During the first phase, scientists began to develop and test methods for reconstructing the radiation doses. To do this, scientists found or reconstructed information about the amount and type of radionuclides that were released from Hadford facilities, where they traveled in environment, and how they reached people. Information about the people who could have been exposed was also found or reconstructed. Scientists then developed a computer model that can estimate doses from radiation exposure received many years ago. All the information that had been gathered was fed into the computer model. Then scientists did a test run'' to see whether the model was working properly. As part of its test run,'' scientists asked the computer model to generate two types of preliminary results: amounts of radionuclides in the environment (air, soil, pasture grass, food, and milk) and preliminary doses people could have received from all the routes of radiation exposure, called exposure pathways. Preliminary dose estimates were made for categories of people who shared certain characteristics and for the Phase 1 population as a whole. 26 refs., 48 figs.

  14. Intensity Modulated Radiation Therapy With Dose Painting to Treat Rhabdomyosarcoma

    SciTech Connect (OSTI)

    Yang, Joanna C.; Dharmarajan, Kavita V.; Wexler, Leonard H.; La Quaglia, Michael P.; Happersett, Laura; Wolden, Suzanne L.

    2012-11-01

    Purpose: To examine local control and patterns of failure in rhabdomyosarcoma patients treated with intensity modulated radiation therapy (RT) with dose painting (DP-IMRT). Patients and Methods: A total of 41 patients underwent DP-IMRT with chemotherapy for definitive treatment. Nineteen also underwent surgery with or without intraoperative RT. Fifty-six percent had alveolar histologic features. The median interval from beginning chemotherapy to RT was 17 weeks (range, 4-25). Very young children who underwent second-look procedures with or without intraoperative RT received reduced doses of 24-36 Gy in 1.4-1.8-Gy fractions. Young adults received 50.4 Gy to the primary tumor and lower doses of 36 Gy in 1.8-Gy fractions to at-risk lymph node chains. Results: With 22 months of median follow-up, the actuarial local control rate was 90%. Patients aged {<=}7 years who received reduced overall and fractional doses had 100% local control, and young adults had 79% (P=.07) local control. Three local failures were identified in young adults whose primary target volumes had received 50.4 Gy in 1.8-Gy fractions. Conclusions: DP-IMRT with lower fractional and cumulative doses is feasible for very young children after second-look procedures with or without intraoperative RT. DP-IMRT is also feasible in adolescents and young adults with aggressive disease who would benefit from prophylactic RT to high-risk lymph node chains, although dose escalation might be warranted for improved local control. With limited follow-up, it appears that DP-IMRT produces local control rates comparable to those of sequential IMRT in patients with rhabdomyosarcoma.

  15. Outline History Basic Theory Research Future Accelerators References Brief Overview of Wakefield

    E-Print Network [OSTI]

    Budker, Dmitry

    Outline History Basic Theory Research Future Accelerators References Brief Overview of Wakefield Overview of Wakefield Acceleration #12;Outline History Basic Theory Research Future Accelerators References of Wakefield Acceleration #12;Outline History Basic Theory Research Future Accelerators References Wakefield

  16. Introduction Luminance and Chrominance High Frequency Content References Smoke Detection in Stationary Video Using

    E-Print Network [OSTI]

    Knaust, Helmut

    Introduction Luminance and Chrominance High Frequency Content References Smoke Detection and Chrominance High Frequency Content References The Problem The Problem: VIDEO: #12;Introduction Luminance and Chrominance High Frequency Content References Fire/Smoke Detection Techniques Standard techniques for fire

  17. Learning user modelling strategies for adaptive referring expression generation in spoken dialogue systems 

    E-Print Network [OSTI]

    Janarthanam, Srinivasan Chandrasekaran

    2011-06-30

    We address the problem of dynamic user modelling for referring expression generation in spoken dialogue systems, i.e how a spoken dialogue system should choose referring expressions to refer to domain entities to users ...

  18. Direct examination of cadmium bonding in rat tissues dosed with mine wastes and cadmium-containing solutions

    SciTech Connect (OSTI)

    Diacomanolis, V.; Ng, J. C. [University of Queensland, National Research Centre for Environmental Toxicology, Coopers Plains, QLD, 4008 (Australia); Sadler, R. [School of Public Health, Griffith University, Brisbane, QLD (Australia); Harris, H. H. [School of Chemistry and Physics, University of Adelaide, Adelaide, SA (Australia); Nomura, M. [Photon Factory, Institute of Material Structure Science, Tsukuba (Japan); Noller, B. N. [University of Queensland, Centre For Mined Land Rehabilitation, St Lucia 4072 QLD (Australia)

    2010-06-23

    Direct examination by XANES and EXAFS of metal bonding in tissue can be demonstrated by examining cadmium uptake and bonding in animal tissue maintained at cryogenic temperatures. XANES at the K-edge of cadmium were collected at the Photon Factory Advanced Ring (PF-AR), NW10A beam line at KEK-Tsukuba-Japan. Rats fed with 1g mine waste containing 8-400 mg/kg cadmium per 200g body weight (b.w.) or dosed by oral gavage with either cadmium chloride solution alone (at 6 mg/kg b.w.) or in combination with other salts (As, Cu or Zn), 5 days/week for 6 weeks, had 0.1-7.5 and 8-86 mg/kg cadmium in the liver or kidney, respectively. Rats given intraperitoneally (ip) or intravenously (iv) 1-4 times with 1 mg/kg b.w. cadmium solution had 30-120 mg/kg cadmium in the liver or kidney. Tissues from rats were kept and transferred at cryogenic temperature and XANES were recorded at 20 K. The spectra for rat liver samples suggested conjugation of cadmium with glutathione or association with the sulfide bond (Cd-S) of proteins and peptides. EXAFS of rat liver fed by Cd and Zn solutions showed that Cd was clearly bound to S ligands with an inter-atomic distance of 2.54 A ring for Cd-S that was similar to cadmium sulfide with an inter-atomic distance of 2.52 A ring for Cd-S. Liver or kidney of rats fed with mine wastes did not give an edge in the XANES spectra indicating little uptake of cadmium by the animals. Longer and higher dosing regimen may be required in order to observe the same Cd-S bond in the rat tissue from mine wastes, including confirmation by EXAFS.

  19. References for radioactive releases to the Columbia River from Hanford Operations, 1944--1957. Letter report: Hanford Environmental Dose Reconstruction Project

    SciTech Connect (OSTI)

    Hall, R.B.

    1991-11-01

    A search was made for published documents related to discharges of radioactive material from Hanford Site facilities to the Columbia River from 1944--1957. The purpose was to list documents that contain data that might be useful in developing a source term for waterborne releases. Source term development work will take place in FY 1992, and FY 1993. This tabulation of published summaries of release data shows the type of measurements that were being made from 1944--1957 and the magnitude of discharges to the Columbia River. In the early years, very little data were collected that related to specific radionuclides. However, most of the key radionuclides were known to be present in effluents from occasional specific radionuclide analyses.

  20. Analysis Approach and Data Package for Mayak Public Doses

    SciTech Connect (OSTI)

    Eslinger, Paul W.; Napier, Bruce A.

    2013-09-18

    Historical activities at facilities producing nuclear materials for weapons released radioactivity into the air and water. Past studies in the United States have evaluated the release, atmospheric transport and environmental accumulation of 131I from the nuclear facilities at Hanford in Washington State and the resulting dose to members of the public (Farris et al. 1994). A multi-year dose reconstruction effort (Mokrov et al. 2004) is also being conducted to produce representative dose estimates for members of the public living near Mayak, Russia, from atmospheric releases of 131I at the facilities of the Mayak Production Association. The approach to calculating individual doses to members of the public from historical releases of airborne 131I has the following general steps: • Construct estimates of releases 131I to the air from production facilities. • Model the transport of 131I in the air and subsequent deposition on the ground and vegetation. • Model the accumulation of 131I in soil, water and food products (environmental media). • Calculate the dose for an individual by matching the appropriate lifestyle and consumption data for the individual to the concentrations of 131I in environmental media at their residence location. A number of computer codes were developed to facilitate the study of airborne 131I emissions at Hanford. Of particular interest is DESCARTES code that modeled accumulation of 131I in environmental media (Miley et al. 1994). In addition, the CIDER computer code estimated annual doses to individuals (Eslinger et al. 1994) using the equations and parameters specific to Hanford (Snyder et al. 1994). Several of the computer codes developed to model 131I releases from Hanford are general enough to be used for other facilities. Additional codes have been developed, including the new individual dose code CiderF (Eslinger and Napier 2013), and applied to historical releases of 131I from Mayak. This document provides a data package that identifies computer code runs and associated input and output files prepared for the purpose of calculating doses to members of the public from atmospheric releases of 131I at the Mayak Production Association for the time period 1948 through 1972.

  1. Library and Information Services Division Current References 2008-2

    E-Print Network [OSTI]

    Library and Information Services Division Current References 2008-2 (Rev. August 2012) National Oceanographic Data Center Publications and Products in the NOAA Central Library Network, 1961-2012 A Bibliography Prepared by Anna Fiolek with contribution from Chris Belter NOAA Central Library 1315 East

  2. Library and Information Services Division Current References 2008-2

    E-Print Network [OSTI]

    Library and Information Services Division Current References 2008-2 National Oceanographic Data, and Information Service National Oceanographic Data Center NOAA Central Library November 2008, Rev. September 2009 Center Publications and Products in the NOAA Central Library Network, 1961-Present A Bibliography

  3. Library and Information Services Division Current References 2008-2

    E-Print Network [OSTI]

    Library and Information Services Division Current References 2008-2 (Revised, May 2015) National Oceanographic Data Center Publications and Products in the NOAA Central Library Network, 1961-2015 A Bibliography Prepared by Anna Fiolek and Chris Belter NOAA Central Library 1315 East-West Highway, Silver

  4. A Reference Architecture for Mobile Code Offload in Hostile Environments

    E-Print Network [OSTI]

    Satyanarayanan, Mahadev "Satya"

    , glewis, ejm}@sei.cmu.edu {krha, satya}@cs.cmu.edu Abstract. Handheld mobile technology is reaching firstA Reference Architecture for Mobile Code Offload in Hostile Environments Soumya Simanta,1 Kiryonh language processing, decision making, and mission planning. However, these applications are computation

  5. Environmental Guidance Program Reference Book: American Indian Religious Freedom Act

    SciTech Connect (OSTI)

    Not Available

    1987-11-01

    This Reference Book contains a copy of the American Indian Religious Freedom Act and guidance for DOE compliance with the statute. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Updates that include important new requirements will be provided periodically.

  6. Creating a Professional Portfolio Ready ReferenceE-12

    E-Print Network [OSTI]

    Creating a Professional Portfolio Ready ReferenceE-12 College of Engineering, Architecture & Technology Career Services Portfolios aren't just for artists anymore. Long regarded as an essential job effort and time. The Low and High Tech Alternatives You may design a high tech or low tech portfolio

  7. Researching a Company Online Ready Reference D-13

    E-Print Network [OSTI]

    Researching a Company Online Ready Reference D-13 College of Engineering, Architecture & Technology information on over 50,000 public and private companies (www.hoovers.com). · CorpTech Database of High and private high-tech organizations (www.corptech.com). · Companies Online from Dun & Bradstreet and Lycos

  8. Technical Reference on Hydrogen Compatibility of Materials Austenitic Stainless Steels

    E-Print Network [OSTI]

    Siefert, Chris

    and corrosion resistance. Type 304 stainless steel is, however, susceptible to strain- induced martensitic in austenitic stainless steels, a' martensite, is associated with lower resistance to hydrogen embrittlementTechnical Reference on Hydrogen Compatibility of Materials Austenitic Stainless Steels: Type 304

  9. Reference wind farm selection for regional wind power prediction models

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    1 Reference wind farm selection for regional wind power prediction models Nils Siebert George.siebert@ensmp.fr, georges.kariniotakis@ensmp.fr Abstract Short-term wind power forecasting is recognized today as a major requirement for a secure and economic integration of wind generation in power systems. This paper deals

  10. Wind Energy Learning Curves for Reference in Expert Elicitations

    E-Print Network [OSTI]

    Mountziaris, T. J.

    Wind Energy Learning Curves for Reference in Expert Elicitations Sarah Mangels, Erin Baker. Abstract: This study presents future projections of wind energy capacity and cost based on historical data. The study will be used during wind- energy expert elicitations (formal interviews aimed to quantify

  11. Reference: RGL 84-07 Subject: MAPPING PIPELINES

    E-Print Network [OSTI]

    US Army Corps of Engineers

    Reference: RGL 84-07 Subject: MAPPING PIPELINES Title: CHARTING OF PIPELINES AND CABLES Issued: 05/01/84 Expires: 12/31/86 Originator: DAEN-CWO-N Description: REQUIRES MAPPING OF PIPELINE CROSSINGS ON NAUTICAL and pipeline crossings on nautical charts published by the Government. This policy is contained in 33 CFR 209

  12. Technical Reference Compilation and Review of Data Standards

    E-Print Network [OSTI]

    Technical Reference Compilation and Review of Data Standards and Application to the Genomes to Life for the Genomes to Life Program Document 2: Compilation of Data Standards for Proteomic and Transcriptomic Experimental Data Document 3: Compilation of Data Formats and XMLs Applicable to Scientific and Analytical Data

  13. User's and Programmer's Reference One-Button Power Measurements

    E-Print Network [OSTI]

    Anlage, Steven

    Spectrum Analyzers Refer to Volume 1 for core spectrum analyzer information. This manual provides Updates: http://www.agilent.com/find/emailupdates · Information on preventing spectrum analyzer damage can Documentation is updated periodically. · For the latest information about Agilent Technologies PSA Spectrum

  14. User's/Programmer's Reference Core Spectrum Analyzer Functions

    E-Print Network [OSTI]

    Anlage, Steven

    User's/Programmer's Reference Volume 1 Core Spectrum Analyzer Functions ESA Series Spectrum. For the latest information about Agilent Technologies ESA Spectrum Analyzers, including firmware upgrades and used under license. NOTE If the ESA Spectrum Analyzer experiences a rapid "power down / power up

  15. Reference-Free Comparative Genomics of 174 Chloroplasts

    E-Print Network [OSTI]

    Reference-Free Comparative Genomics of 174 Chloroplasts Chai-Shian Kua1,2 , Jue Ruan3 , John's Republic of China, 3 The CAS Key Laboratory of Genome Science and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, People's Republic of China, 4 Department of Biological

  16. Finance Committee Terms of Reference, Membership and Operating Procedures

    E-Print Network [OSTI]

    Botea, Adi

    95/2012 Finance Committee ­ Terms of Reference, Membership and Operating Procedures Principles 1 on, or pose any reasonable risk to, the University's finances and operations" section 18(4)(d). 3. Council has established a Finance Committee as a committee of Council. 4. The broad purpose of the Finance

  17. Request for Reference Department of Chemistry and Biochemistry

    E-Print Network [OSTI]

    de Lijser, Peter

    Request for Reference Department of Chemistry and Biochemistry Phone: (657) 278-3621 / Fax: (657 of Interest: Analytical Inorganic Organic Physical Biochemistry OPTIONAL: I hereby waive my right with your letter to: Graduate Program Adviser, Department of Chemistry & Biochemistry, California State

  18. Shape Recipes: Scene Representations that Refer to the Image

    E-Print Network [OSTI]

    Torralba, Antonio

    Shape Recipes: Scene Representations that Refer to the Image William T. Freeman and Antonio- resentation, called a scene recipe, that relies on the image itself to de- scribe the complex scene configurations. Shape recipes are an example: these are the regression coefficients that predict the bandpassed

  19. sheet is a su se refer to t

    E-Print Network [OSTI]

    Refer to your Search the on number for e f your course select will aut Make sure yo Build your tim at http://w in, build you departmenta nline course t ach course e includes a la tomatically sc ou pick nrolling stration and E website for in exchange a co ow the instruc explanation p button different lab

  20. A Configurable Reference Modelling Language1 M. Rosemanna

    E-Print Network [OSTI]

    van der Aalst, Wil

    , Configuration, Event-driven Process Chains 1 This research project is financially supported by SAP Corporate reference models "just" depict the possible system capabilities and cannot sufficiently guide the project, Eindhoven, The Netherlands, w.m.p.v.d.aalst@tm.tue.nl Abstract Enterprise Systems (ES) are comprehensive off