Ohka Kogyo TOK Jump to: navigation, search Name: Tokyo Ohka Kogyo (TOK) Place: Tokyo, Japan Product: TOK makes photoresists for semiconductor, flat panel display, printed wiring...
Tok School's use of a biomass combined heat and power system is helping the school to save on energy costs.
savings, Tok School has been able to rehire three staff members for the school: music teacher, counselor, and boiler operator. Once more savings are realized and biomass...
Because of the biomass CHP project's anticipated and realized savings, Tok School has been able to rehire three staff members for the school: music teacher, counselor, and boiler ...
and Power | Department of Energy Alaska Gateway School District Adopts Combined Heat and Power EERE Success Story-Alaska Gateway School District Adopts Combined Heat and Power May 7, 2013 - 12:00am Addthis In Tok, Alaska, the economic impact of high fuel prices was crippling the community's economy, especially for the Alaska Gateway School District, with staff laid off and double duties assigned to many. To help offset high energy costs, the school district decided to replace its
Sissons, C.H.; Sharrock, K.R.; Daniel, R.M.; Morgan, H.W.
Avicel enrichment cultures from 47 thermal-pool sites in the New Zealand Rotorua-Taupo region were screened for growth and carboxymethyl cellulase activity at 75/sup 0/C. Eight anaerobic cellulolytic cultures were obtained. The effect of temperature on carboxymethyl cellulase activity was measured, and bacteria were isolated from the five best cultures. Bacteria from two sources designated TP8 and TP10 grew at 75/sup 0/C, accumulated reducing sugar in the growth medium and gave free cellulases with avicelase activity. Bacteria from sources designated Tok4, Tok8, and Wai21 grew at 75/sup 0/C, accumulated no free sugars in the medium, and gave free carboxymethyl cellulases with virtually no avicelase activity. All were obligate anaerobic nonsporeforming rods which stained gram pentoses as well as hexoses, and gave ethanol and acetate as major fermentation end products. The isolated strain which produced the most active and stable cellulases had lower rates of free endocellulase accumulation at 75/sup 0/C than did Clostridium thermocellum at 60/sup 0/C, but its cellulase activity against avicel and filter paper in culture supernatants was comparable. Tested at 85/sup 0/C, TP8.T carboxymethyl cellulases included components which were very stable, whereas C. thermocellum carboxymethyl cellulases were all rapidly inactivated. The TP8.T avicelase activity was relatively unaffected by Triton X-100, EDTA, and dithiothreitol. Evidence was obtained for the existence of unisolated, cellulolytic extreme thermophiles producing cellulases which were more stable and active than those from TP8.T.
This report summarizes the status of Wankel rotary engine technology, particularly as applicable to highway vehicles. The Wankel engine was invented over 25 years ago, and has undergone continual evolutionary design refinement. The engine's perceived advantages of less weight, volume, and complexity than reciprocating engines sparked keen interest, and Wankel-powered automobiles have now been in production for almost 20 years. However, in the early 1970s interest in the Wankel engine greatly subsided because of two problems with the engine at that time: poor fuel economy and high hydrocarbon emissions. The bulk of current Wankel engine development work applicable to highway vehicles is being conducted by Toyo Kogyo (TK) and Curtiss-Wright (C-W). TK has manufactured over 1.2 million rotary engines to date, and markets them in the Mazda Luce and Cosmo in Japan and the Mazda RX-7 worldwide. State-of-the-art production rotary-powered vehicles from TK now exhibit fuel economy which appears to be competitive with many equal-performance, reciprocating-engine vehicles. C-W is focusing its efforts on direct-injection, stratified-charge designs for military and aircraft applications. The company is developing a 750-hp dual-rotor engine for the US Marine Corps, and has completed a design study for a 320-hp general aviation engine. Based on typical reciprocating engines of 1975 to 1977 vintage, and with final drive ratios adjusted to give roughly equal vehicle performance, calculated Environmental Protection Agency (EPA) city fuel economy with the C-W rotary averages 25% higher than with the reciprocating engine. The highway gain is 13%. Use of diesel fuel or a middle distillate instead of gasoline allows an additional 11% gain to be projected on a per-gallon basis. In addition, further gains of 14 to 38% are projected to result from use of a smaller turbocharged version of the engine.
Xie, Hongzhi; Mukundan, Harshini; Martinez, Jennifer S; Swanson, Basil I; Anderson, Aaron S; Grace, Kevin
The quantitative, simultaneous detection of multiple biomarkers with high sensitivity and specificity is critical for biomedical diagnostics, drug discovery and biomarker characterization [Wilson 2006, Tok 2006, Straub 2005, Joos 2002, Jani 2000]. Detection systems relying on optical signal transduction are, in general, advantageous because they are fast, portable, inexpensive, sensitive, and have the potential for multiplex detection of analytes of interest. However, conventional immunoassays for the detection of biomarkers, such as the Enzyme Linked Immunosorbant Assays (ELISAs) are semi-quantitative, time consuming and insensitive. ELISA assays are also limited by high non-specific binding, especially when used with complex biological samples such as serum and urine (REF). Organic fluorophores that are commonly used in such applications lack photostability and possess a narrow Stoke's shift that makes simultaneous detection of multiple fluorophores with a single excitation source difficult, thereby restricting their use in multiplex assays. The above limitations with traditional assay platforms have resulted in the increased use of nanotechnology-based tools and techniques in the fields of medical imaging [ref], targeted drug delivery [Caruthers 2007, Liu 2007], and sensing [ref]. One such area of increasing interest is the use of semiconductor quantum dots (QDs) for biomedical research and diagnostics [Gao and Cui 2004, Voura 2004, Michalet 2005, Chan 2002, Jaiswal 2004, Gao 2005, Medintz 2005, So 2006 2006, Wu 2003]. Compared to organic dyes, QDs provide several advantages for use in immunoassay platforms, including broad absorption bands with high extinction coefficients, narrow and symmetric emission bands with high quantum yields, high photostablility, and a large Stokes shift [Michalet 2005, Gu 2002]. These features prompted the use of QDs as probes in biodetection [Michalet 2005, Medintz 2005]. For example, Jaiswal et al. reported long term multiple color imaging of live cells using QD-bioconjugates [Jaiswal 2003]. Gao [Gao 2004] and So [So 2006] have used QDs as probes for in-vivo cancer targeting and imaging. Medintz et al. reported self-assembled QD-based biosensors for detection of analytes based on energy transfer [Medintz 2003]. Others have developed an approach for multiplex optical encoding of biomolecules using QDs [Han 2001]. Immunoassays have also benefited from the advantages of QDs. Recently, dihydrolipoic acid (DHLA) capped-QDs have been attached to antibodies and used as fluorescence reporters in plate-based multiplex immunoassays [Goodman 2004]. However, DHLA-QDs are associated with low quantum efficiency and are unstable at neutral pH. These problems limit the application of this technology to the sensitive detection of biomolecules, especially in complex biological samples. Thus, the development of a rapid, sensitive, quantitative, and specific multiplex platform for the detection of biomarkers in difficult samples remains an elusive target. The goal stated above has applications in many fields including medical diagnostics, biological research, and threat reduction. The current decade alone has seen the development of a need to rapidly and accurately detect potential biological warfare agents. For example, current methods for the detection of anthrax are grossly inadequate for a variety of reasons including long incubation time (5 days from time of exposure to onset of symptoms) and non-specific ('flu-like') symptoms. When five employees of the United State Senate were exposed to B. anthracis in the mail (2001), only one patient had a confirmed diagnosis before death. Since then, sandwich immunoassays using both colorimetric and fluorescence detectors have been developed for key components of the anthrax lethal toxin, namely protective antigen (PA), lethal factor (LF), and the edema factor [Mourez 2001]. While these platforms were successful in assays against anthrax toxins, the sensitivity was poor. Furthermore, no single platform exists for the simultaneous and quantitative detection of mul