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Sample records for nick braden appa

  1. APPA Customer Connections Conference

    Broader source: Energy.gov [DOE]

    The Customer Connections Conference is APPA's annual meeting for utility professionals in the areas of:

  2. Nick Buraglio

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Nick Buraglio Engineering Services The Network OSCARS Fasterdata IPv6 Network Network Performance Tools The ESnet Engineering Team Contact Us Technical Assistance: 1 800-33-ESnet (Inside US) 1 800-333-7638 (Inside US) 1 510-486-7600 (Globally) 1 510-486-7607 (Globally) Report Network Problems: trouble@es.net Provide Web Site Feedback: info@es.net Nick Buraglio Nick Buraglio Network Engineer buraglio@es.net

  3. 2015 APPA National Conference

    Broader source: Energy.gov [DOE]

    The American Public Power Association (APPA) is hosting their national conference that covers the political, economic, and technological trends shaping the electric utility industry.

  4. Nick Buraglio

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Nick Buraglio About ESnet Our Mission The Network ESnet History Governance & Policies Career Opportunities ESnet Staff & Org Chart Administration Advanced Network Technologies Cybersecurity Infrastructure, Identity & Collaboration Network Engineering Network Planning Operational Enhancements Office of the CTO Science Engagement Tools Team Contact Us Contact Us Technical Assistance: 1 800-33-ESnet (Inside US) 1 800-333-7638 (Inside US) 1 510-486-7600 (Globally) 1 510-486-7607

  5. NickL's blog

    Open Energy Info (EERE)

    Oct 2015 21:19:38 +0000 NickL 1717 at http:en.openei.orgcommunity The Upshot and Innovation of the Green Button Initiative http:en.openei.orgcommunityblog...

  6. APPA Engineering and Operations Technical Conference

    Broader source: Energy.gov [DOE]

    The 2014 APPA Engineering and Operations Technical Conference is designed for public power professionals charged with designing, developing, and maintaining the nation's electric system.

  7. Asociacion de Productores de Energias Renovables APPA | Open...

    Open Energy Info (EERE)

    Productores de Energias Renovables APPA Jump to: navigation, search Name: Asociacion de Productores de Energias Renovables (APPA) Place: Spain Sector: Renewable Energy Product:...

  8. NREL: Energy Analysis - Nick Grue

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Nick Grue Nick Grue is a member of the Data Analysis and Visualization Group in the Strategic Energy Analysis Center. Scientist II - GIS On staff since June 2014 Phone number: 303-384-7278 E-mail: nick.grue@nrel.gov Areas of expertise Geospatial analysis Web GIS Primary research interests Open source energy data Web visualization of energy data Renewable energy policy Education and background training B.A. in Geography and Environmental Science, University of Colorado at Denver, Denver, CO, 2012

  9. NREL: Energy Analysis - Nick Langle

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Langle Photo of Nick Langle. Nick Langle is a member of the Data Analysis and Visualization Group in the Strategic Energy Analysis Center. Front-End Web Engineer On staff since July 2010 Phone number: 303-275-3775 E-mail: nicholas.langle@nrel.gov Areas of expertise HTML/CSS/Javascript/jQuery UI/UX Responsive web design Semantic MediaWiki SEO Primary research interests Web design and usability Data visualization and analytics Geospatial analysis Transportation and alternative fuels Industrial

  10. Nick Wright Named Advanced Technologies Group Lead

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Nick Wright Named Advanced Technologies Group Lead Nick Wright Named Advanced Technologies Group Lead February 4, 2013 Nick Nick Wright has been named head of the National Energy Research Scientific Computing Center's (NERSC) Advanced Technologies Group (ATG), which focuses on understanding the requirements of current and emerging applications to make choices in hardware design and programming models that best serve the science needs of NERSC users. ATG specializes in benchmarking, system

  11. Rapporteurs Report: Tom Lograsso, Ames Laboratory and Nick Morley...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Rapporteurs Report: Tom Lograsso, Ames Laboratory and Nick Morley, Oakdene Hollins Rapporteurs Report: Tom Lograsso, Ames Laboratory and Nick Morley, Oakdene Hollins Microsoft...

  12. Mr. Nick Proto Ralph Ferrara, Inc.

    Office of Legacy Management (LM)

    Department of Energy Washington, DC 20585 Mr. Nick Proto Ralph Ferrara, Inc. 601 West 26th ... It is the policy of the Department of Energy to independently verify that remedial ...

  13. NREL: Photovoltaics Research - Nick Bosco, PhD

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Nick Bosco, PhD Senior Scientist Photo of vv 303-384-6337 Nick.Bosco@nrel.gov Task Focus: Failure Analysis and Accelerated Testing Specializes in: Infrared imaging and other...

  14. NERSC Nick Balthaser NERSC Storage Systems Group

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Introduction to HPSS at NERSC Nick Balthaser NERSC Storage Systems Group nabalthaser@lbl.gov Joint Genome Institute, Walnut Creek, CA Feb 10, 2011 * NERSC Archive Technologies Overview * Use Cases for the Archive * Hands-on: - Authentication - Client Usage and Examples * Client Installation Agenda 2 * Current data volume: 12PB in 100M files written to 26k tapes (user system) * Permanent storage is magnetic tape, disk cache is transient - All data written to HPSS goes through the disk cache -

  15. Geek-Up[12.23.2010]: Muons at the South Pole and Dr. Nick Holoynak |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy 2.23.2010]: Muons at the South Pole and Dr. Nick Holoynak Geek-Up[12.23.2010]: Muons at the South Pole and Dr. Nick Holoynak December 23, 2010 - 12:05pm Addthis Illustration of the IceCube neutrino observatory. Source: LBNL Illustration of the IceCube neutrino observatory. Source: LBNL Niketa Kumar Niketa Kumar Public Affairs Specialist, Office of Public Affairs Earlier today, the Energy Blog featured Los Alamos National Lab's system to track Santa. However, while there

  16. Nick Johnson

    Broader source: Energy.gov [DOE]

    Mr. Johnson holds a Master's degree in Mechanical Engineering and has been with the U.S. Department of Energy Wind and Water Power Technologies Office for seven years.In his current role, he...

  17. Nick Buraglio

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Opportunities ESnet Staff & Org Chart Administration Advanced Network Technologies Cybersecurity Infrastructure, Identity & Collaboration Network Engineering Office of the CTO...

  18. app_a

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    apm Questions, Comments, and Answers for Draft Request for Proposal Documents Draft RFP Questions, Comments, and Answers-coming soon NNSA projects win Secretary's Achievement Awards for cost savings and efficiency NNSA was presented with two Department of Energy Secretary's Achievement Awards at a ceremony in Arlington, Va., on Wednesday. The awards, presented by Deputy Secretary of Energy Elizabeth Sherwood-Randall, commend NNSA on delivering the Y-12 Nuclear Facility Risk Reduction Project

  19. Nick's Utility | Open Energy Information

    Open Energy Info (EERE)

    Ownership F NERC Location WECC, MAPP NERC MRO Yes NERC SPP Yes NERC WECC Yes ISO CA Yes RTO SPP Yes ISO MISO Yes ISO Other Yes Activity Generation Yes Activity Transmission Yes...

  20. Nick Sinai | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Expanded "Green Button" Will Reach Federal Agencies and More American Energy Consumers December 6 Green Button: Enabling Energy Innovation May 9 Better Building Federal Award ...

  1. NREL: Energy Analysis - Nick Muerdter

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and Visualization Group Energy Forecasting and Modeling Group Market and Policy Impact Analysis Group Technology Systems and Sustainability Analysis Group Washington D.C....

  2. Nick Balthaser! Storage Systems Group

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Storage Systems Group Introduction to Archival Storage at NERSC --- 1 --- February 1 5, 2 013 Agenda * Objec2ves - Describe t he r ole o f a rchival s torage i n a 4 ered s torage s trategy - Log i nto t he N ERSC a rchive - Store a nd r etrieve fi les f rom t he a rchive - Avoid c ommon p roblems * Archive B asics - What i s a n a rchive? - Why s hould I u se o ne? - Features o f t he N ERSC a rchive * Using t he N ERSC A rchive Note: U nix/Linux c ommand---line f amiliarity r equired - How t o

  3. Nick Wright Named Advanced Technologies Group Lead

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    models that best serve the science needs of NERSC users. ATG specializes in benchmarking, system performance, debugging and analysis, workload monitoring, use of...

  4. NERSC Nick Balthaser NERSC Storage Systems Group

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    for performance - FTP-compatible syntax - Scriptable with some effort (Here doc or command file) bash-4.0 pftp -i < cmds.txt * FTP - Available everywhere, but non-parallel,...

  5. Lisa Gerhardt! Nick Balthaser! Storage Systems Group

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ser's h ome d irectory on t he c ompute p laWorm - All N ERSC H PSS c lients u se t he s ame . netrc fi le - The k ey i s I P s pecific. M ust g enerate a n ew k ey f or u se o...

  6. Microsoft Word - S08266_App_A-2.doc

    Office of Legacy Management (LM)

    tabernaemontani SOFT-STEMMED BULRUSH sedge 2 native OBL 5.912% Scirpus atrovirens GREEN BULRUSH sedge 1 native OBL 0.222% Sorghastrum nutans INDIAN GRASS grass 5 native UPL...

  7. Microsoft Word - S08266_App_A-3.doc

    Office of Legacy Management (LM)

    Score 0 Fernald Preserve, Ohio, Wetland Mitigation Monitoring Report U.S. Department of Energy Doc. No. S08266 Appendix A-3, 2011 Amphibian Index of Biotic Integrity Data...

  8. Nick Balthaser! Wayne Hurlbert! LBNL/NERSC Storage Systems Group

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Wayne Hurlbert! LBNL/NERSC Storage Systems Group T10KC Technology in Production --- 1 --- May 9 , 2 013 Agenda * Environment - Number T 10KC d rives - Length o f 9 me i n p roduc9on - Drive f eatures i n u se * Data V olume - Carts, T B, fi les * Workload - Exchanges/unit 9 me - IO R ates: R aw v s. H PSS * Error R ates * Data L oss * Conclusion --- 2 --- Environment * Currently 3 4 T 10KC i n p roducDon - Total p opula9on o f 1 62 O racle/STK t ape d rives i n 4 SL8500s - First s et o f 1 8 C d

  9. Lisa Gerhardt! NERSC User Services! Nick Balthaser! NERSC Storage...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    slowest system ac)vi)es - Average 9 me t o d ata o n c urrent d rive technology i s 4 5s, + 15 - 3 0 s ec c artridge l oad - Reading a f ew l arge fi les f rom t ape i s...

  10. Lisa Gerhardt! NERSC User Services! Nick Balthaser! NERSC Storage...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... n ot o p6mal f or H PSS --- 9 --- Globus Web Transfer * Web i niFated t ransfer --- 1 0 ... o ver f rom t he b eginning * High---latencyunreliable n etworks - HPSS v ery s ...

  11. NickL's blog | OpenEI Community

    Open Energy Info (EERE)

    held a mapathon, focused on three main projects: humanitarian mapping efforts, mapping U.S. parks, and power outage mapping. OpenEI provided support for the Power Utility Areas...

  12. Nick Balthaser! LBNL/NERSC Storage Systems Group LBNL/NERSC Site

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    LBNL/NERSC Site Intro: HPSS in Production --- 1 --- HUF 2 013 November 5, 2013 Agenda * HPSS a t L BNL/NERSC * Client A ccess * Session M anagement a nd F air U sage * System M onitoring * Tape T echnology I ntegraJon * Metrics * Recent C hallenges * The F uture o f H PSS a t N ERSC * Further I nfo --- 2 --- HPSS at LBNL/NERSC * NERSC i s t he p roducJon H PC d ivision a t L BNL - DOE O ffice o f S cience u nclassified r esearch - HPSS d eveloper s ite - ~ 5 000 r emote u sers, d iverse u

  13. Nick Balthaser! LBNL/NERSC Storage Systems Group GlobusOnline...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    a t N ERSC s ince HPSS 5.x - HPSS 5 .x p re---DSI gridFTP a uthenJcaJon c ode f or P FTP d eveloped i n---house - HPSS 6 .2 D SI d eveloped a t A NL * enabled a t N ERSC i n 2...

  14. How ATP3 is Addressing the Challenges of Scale-up in Algae Technology...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Cal Poly Tryg Lundquist Braden Crowe Eric Nicolai Commercial Algae Management Albert Vitale Robert Vitale Georgia Tech Yongsheng Chen Steven Van Ginkel Thomas Igou Zixuan Hu ASU...

  15. QER - Comment of American Public Power Association 2 | Department of Energy

    Energy Savers [EERE]

    2 QER - Comment of American Public Power Association 2 From: Voyles, Seth [svoyles@publicpower.org] Sent: Sunday, May 18, 2014 2:22 PM To: QERcomments CC: Pechman, Carl; Mansueti, Lawrence Subject: Comments on Enhancing Energy Infrastructure Resiliency and Addressing Vulnerabilities Attachment: APPA Statement Submitted to First QER Mtg FINAL 4-15-14 docx.pdf; APPA Testimony for Senate Energy Committee Grid Security Hearing on Apri....pdf Attached are APPA's comments for the first public QER

  16. The Honorable Ernest Moniz

    Broader source: Energy.gov (indexed) [DOE]

    Electric Cooperative Association (NRECA) and the American Public Power Association (APPA) together represent over 1,200 cooperative and publicly owned utilities in 34 states...

  17. In the Matter of National Broadband Plan Request for Information...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    In the Matter of National Broadband Plan Request for Information: Communications Requirements The American Public Power Association ("APPA") appreciates this opportunity to respond ...

  18. Office Of International Affairs Expert Listing 2/25/14 Organization

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... IA-32 European & Asian Pacific Affairs Belgium Nick Sherman 3903 Nick.Sherman@hq.doe.gov Samuel Browne 8724 IA-32 European & Asian Pacific Affairs Bhutan Nick Sherman 3903 ...

  19. Green Button Apps on OpenEI | OpenEI Community

    Open Energy Info (EERE)

    Applications Login to post comments Dc's blog Latest blog posts NickL The Upshot and Innovation of the Green Button Initiative Posted: 22 Jul 2015 - 15:16 by NickL NickL DOE...

  20. Nicholaos Demas | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Photo of Nick Demas Nicholaos Demas Assistant Materials Scientist E-mail ndemas@anl.gov

  1. Questions about OpenEI? | OpenEI Community

    Open Energy Info (EERE)

    posts NickL OpenEI Contacts Posted: 5 Oct 2015 - 14:19 by NickL NickL The Upshot and Innovation of the Green Button Initiative Posted: 22 Jul 2015 - 15:16 by NickL 1 of 206 ...

  2. DOE Releases New Wind Vision Report | OpenEI Community

    Open Energy Info (EERE)

    posts NickL OpenEI Contacts Posted: 5 Oct 2015 - 14:19 by NickL NickL The Upshot and Innovation of the Green Button Initiative Posted: 22 Jul 2015 - 15:16 by NickL 1 of 206 ...

  3. Secret Energy Savings | OpenEI Community

    Open Energy Info (EERE)

    posts NickL OpenEI Contacts Posted: 5 Oct 2015 - 14:19 by NickL NickL The Upshot and Innovation of the Green Button Initiative Posted: 22 Jul 2015 - 15:16 by NickL 1 of 206 ...

  4. Google lends support to the software behind OpenEI.org | OpenEI...

    Open Energy Info (EERE)

    posts NickL OpenEI Contacts Posted: 5 Oct 2015 - 14:19 by NickL NickL The Upshot and Innovation of the Green Button Initiative Posted: 22 Jul 2015 - 15:16 by NickL 1 of 206 ...

  5. NBP RFI: Communications Requirements - Reply Comments of Utilities...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    including those by APPA, EEI and NRECA, as well as API - strongly support utility access to licensed spectrum in order to support smart grid and other CII communications needs. ...

  6. Simplification of Diesel Emission Control System Packaging Using SCR Coated

    Broader source: Energy.gov (indexed) [DOE]

    Power Wind Awards | Department of Energy The U.S. Department of Energy, together with the American Public Power Association (APPA), today recognized the Oklahoma Municipal Power Authority (OMPA) and Silicon Valley Power (SVP) of Santa Clara, California, as the winners of the 2014 Public Power Wind Awards. The awards, presented at the APPA National Conference in Denver, Colorado, recognize publicly owned utilities that demonstrate outstanding leadership in advancing wind power in the United

  7. Green Button FAQ | OpenEI Community

    Open Energy Info (EERE)

    Green Button FAQ Home > Groups > Green Button Applications NickL's picture Submitted by NickL(137) Contributor 21 July, 2014 - 10:02 Green Button The greenbuttondata.org site has...

  8. geospatial data | OpenEI Community

    Open Energy Info (EERE)

    geospatial data Home NickL's picture Submitted by NickL(137) Contributor 25 June, 2012 - 21:45 GIS keyword geospatial data GIS GIS data Explore the geospatial datasets in OpenEI's...

  9. GIS data | OpenEI Community

    Open Energy Info (EERE)

    GIS data Home NickL's picture Submitted by NickL(137) Contributor 25 June, 2012 - 21:45 GIS keyword geospatial data GIS GIS data Explore the geospatial datasets in OpenEI's...

  10. Geospatial | OpenEI Community

    Open Energy Info (EERE)

    Blog entry Discussion Document Event Poll Question Keywords Author Apply NickL Hi-Yes, you are correct wi... Posted by: NickL 10 Sep 2013 - 10:02 Hi- Yes, you are correct...

  11. A question about geographic data on wind farms in the US | OpenEI...

    Open Energy Info (EERE)

    know. Thanks -nick Submitted by Nickc on 10 September, 2013 - 11:52 1 answer Points: 0 Hi Nick- Thank you for posting your question here. One of the most complete wind farm...

  12. Databus | OpenEI Community

    Open Energy Info (EERE)

    Blog entry Discussion Document Event Poll Question Keywords Author Apply NickL Hello-Sorry for the delay in... Posted by: NickL 22 Sep 2015 - 14:33 Hello- Sorry for the...

  13. FRED Overview Slides | OpenEI Community

    Open Energy Info (EERE)

    hybrid power plants? Login to post comments NickL NickL2 years 39 weeks ago Wind Data Hello- There are various types of wind data available. These can be searched for on OpenEI...

  14. QER - Comment of American Public Power Association 7 | Department of Energy

    Energy Savers [EERE]

    7 QER - Comment of American Public Power Association 7 From: Voyles, Seth [svoyles@publicpower.org] Sent: Thursday, August 28, 2014 9:43 AM To: QERcomments Subject: Comment on: QER Public Meeting in Denver, CO: Gas-Electricity Interdependence Attachment: AttachB_Aspen_GasStorage2012.pdf; APPA Statement for the Record nat gas forum 2013-06-10.pdf; APPA Statement for the Record nat gas VERs hearing final 2013-05-09.pdf Attached are several documents for consideration for the QER Public Meeting on

  15. Y-12 Bulletin Uranium Articles | Y-12 National Security Complex

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Nuclear Security Administration Apprentice Program celebrates third graduating class Thursday, March 13, 2014 - 3:00pm The Y-12 Apprentice Program recently celebrated its third graduating class as 27 participants gained their journeyman status. Each graduate spent three to four years with a journeyman and attended between 144 and 246 hours of classroom training each year on his or her own time, usually in the evenings at local union halls. Those graduating include Adam Braden, Daniel Brown,

  16. PowerPoint Presentation

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Meet the Challenge Team Nay Chehab Communications Lead Carrie Giles & Carrie Ryder Recruitment and Account Management Peter Heywood Ambassador Lead Sarah Olexsak Coordinator Nick ...

  17. Enron Documents

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... General Motors Nick Pfeiffer Engineering Manager Mogas Fuel Systems Semarnap-Procuraduria del Medio Ambiente Gaz de France Secretario del Medio Ambiente -- Session 6 Future ...

  18. TransportToolkit Prototype | Open Energy Information

    Open Energy Info (EERE)

    AgencyCompany Organization: Nick Langle ComplexityEase of Use: Not Available Cost: Free Transport Toolkit Region(s): Asia, Europe, Africa & Middle East, Australia & North...

  19. Nicholas Balthaser

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    analyst at Wells Fargo Bank. Before joining the Storage Systems Group Nick managed Linux compute platforms in the Computational Systems Group and administered FreeBSD systems...

  20. TITLE AUTHORS SUBJECT SUBJECT RELATED DESCRIPTION PUBLISHER AVAILABILI...

    Office of Scientific and Technical Information (OSTI)

    Deep Bed Adsorption Testing using Silver Functionalized Aerogel Nick Soelberg Tony Watson MGMT OF RADIOACTIVE AND NON RADIOACTIVE WASTES FROM NUCLEAR FACILITIES aerogel iodine...

  1. Deep Bed Adsorption Testing using Silver-Functionalized Aerogel...

    Office of Scientific and Technical Information (OSTI)

    Bed Adsorption Testing using Silver-Functionalized Aerogel Nick Soelberg; Tony Watson 12 MGMT OF RADIOACTIVE AND NON-RADIOACTIVE WASTES FROM NUCLEAR FACILITIES aerogel; iodine...

  2. United Nations Environment Programme (UNEP)-Finance Initiative...

    Open Energy Info (EERE)

    Generale (France) Standard Chartered (United Kingdom) Sustainable Asset Management (SAM) (Switzerland) SwissRe (Switzerland) UBS (Switzerland) Chairs Nick Robins, HSBC...

  3. OAHU Wind Integration And Transmission Study: Summary Report...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... University College Dublin Dale Osborn Midwest ISO Steve Pullins Horizon Energy Group Henry ... WORK TEAM MEMBERS Devon Manz, Nick Miller, Sebastian Achilles, Gene Hinkle, Reigh ...

  4. GIS keyword | OpenEI Community

    Open Energy Info (EERE)

    Open government map data initiatives in the USA or Canada? IRENA launches global atlas of renewable energy potential more Group members (8) Managers: NickL Recent members:...

  5. EM Newsletters | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Dave Olson, WRPS president and project manager; Jennie Weber, ESD's eastern regional director; and Nick Erickson, the local veterans' employment representative. State Honors...

  6. Search for: All records | DOE PAGES

    Office of Scientific and Technical Information (OSTI)

    T. ; Posewitz, Matthew C. May 2015 , Elsevier Combined algal processing: A novel ... Nick Full Text Available January 2016 , Elsevier The effects of physical and chemical ...

  7. Organizational Chart

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    John Shalf Jeff Broughton Katie Antypas Jay Srinivasan Nick Wright Brent Draney Elizabeth Bautista Shane Cannon Prabhat David Skinner Richard Gerber Damian Hazen Last edited:...

  8. Cosmological Simulations for Sky Surveys

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Nick Gnedin (FNAL), Katrin Heitmann (ANL), David Higdon (LANL), Peter Nugent (LBNL), Rob Ross (ANL), Anze Slosar (BNL), Risa Wechsler (SLAC), Martin White (UC Berkeley) NERSC...

  9. Final Report on Experimental and Numerical Modeling Activities...

    Office of Scientific and Technical Information (OSTI)

    Authors: Mukhopadhyay, Sumit ; Spycher, Nicolas ; Pester, Nick ; Saldi, Giuseppe ; Beyer, John ; Houseworth, Jim ; Knauss, Kevin Publication Date: 2014-09-04 OSTI Identifier: ...

  10. Operated by Los Alamos National Security, LLC for NNSA U N C...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    John Morrison Nick Nagy Randal Rheinheimer Norbert Seifert Randy Smith Bob Tomlinson Philip Ulibarri Mark Vernon Andy White ... Operated by Los Alamos National Security, LLC for...

  11. Mark Caffarey, UMICORE, "Opportunities and Limits to Recycling...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    icon SessionC4Caffarey.ppt More Documents & Publications Rapporteurs Report: Tom Lograsso, Ames Laboratory and Nick Morley, Oakdene Hollins 2010 Critical Materials...

  12. Slide 1

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Acknowledgments * LBLNERSC - John Shalf - Prabhat - Wes Bethel - Andrew Uselton - Noel Keen - Hongzhang Shan - Katie Antypas - Shane Canon - David Skinner - Nick Wright *...

  13. Apps for Energy Challenge | OpenEI Community

    Open Energy Info (EERE)

    winners from the challenge are listed among the featured apps. Public voting is still open. Groups: Green Button Applications Login to post comments Latest discussions NickL...

  14. DOE FINAL TECHNICAL REPORT RP

    SciTech Connect (OSTI)

    RUSS PETERMAN

    2012-01-01

    The City of Georgetown Utility Systems (GUS) patnered with the private sector, the American Public Power Association (APPA) and Southwestern University to design, construct, test and monitor a solar co-generation system directly connected to the GUS electric distribution system. This report consists of the Primary Technical Report and 3 attachments.

  15. EIS-0386: Final Programmatic Environmental Impact Statement ...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    PDF icon EIS-0386-FEIS-Vol2-FrontMatter-2008.pdf PDF icon EIS-0386-FEIS-Vol2-AppA-2008.pdf PDF icon EIS-0386-FEIS-Vol2-AppB-2008.pdf PDF icon EIS-0386-FEIS-Vol2-AppC-20...

  16. Student Spotlight

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Spotlight Mekena McGrew Single-shot, Second Harmonic Generation Frequency Resolved Optical Gating (SHG FROG) system for damage testing. Nick Zobrist Optics inspection algorithms that evaluate the condition of NIF's optics. Maverick Chea Optimization of Ultrathin Films Alexandra Carlson Image Analysis Classification algorithm to automatically classify NIF optics damage sites. Nick Czapla Characterizing Scatter Plate Material

  17. QER- Comment of American Public Power Association 1

    Broader source: Energy.gov [DOE]

    Attached are the American Public Power Association 's (APPA) statement for the April 11 QER public meeting, Duane Highley's statement for the same meeting since we reference it, and Sue Kelly's (APPA President & CEO) testimony from last Thursday's (April 10) Senate Energy and Natural Resources Committee hearing entitled "Keeping the Lights On – Are We Doing Enough to Ensure the Reliability and Security of the US Electric Grid?" since her testimony covers everything in regards to this meeting. Thank you in advance for your consideration of our attached documents for the QER. Please let me know if you have any questions. Best, Seth Seth Voyles Director, Government Relations 1875 Connecticut Ave., NW, Suite 1200, Washington, D.C. 20009-5715 www.publicpower.org

  18. Silicon Valley Power and Oklahoma Municipal Power Authority Win 2014 Public

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Power Wind Awards | Department of Energy Silicon Valley Power and Oklahoma Municipal Power Authority Win 2014 Public Power Wind Awards Silicon Valley Power and Oklahoma Municipal Power Authority Win 2014 Public Power Wind Awards June 17, 2014 - 8:17am Addthis The U.S. Department of Energy, together with the American Public Power Association (APPA), today recognized the Oklahoma Municipal Power Authority (OMPA) and Silicon Valley Power (SVP) of Santa Clara, California, as the winners of the

  19. Energy Bill Literature Sources

    Energy Savers [EERE]

    of the "PURPA Standards" in the Energy Independence and Security Act of 2007 August 11, 2008 Sponsored by American Public Power Association (APPA) Edison Electric Institute (EEI) National Association of Regulatory Utility Commissioners (NARUC) National Rural Electric Cooperative Association (NRECA) Prepared by: Kenneth Rose and Mike Murphy iii Preface This manual was prepared by Kenneth Rose, a consultant and Senior Fellow at the Institute of Public Utilities at Michigan State

  20. Energy Bill Literature Sources

    Energy Savers [EERE]

    Of the "PURPA Standards" in the Energy Policy Act of 2005 March 22, 2006 Sponsored by American Public Power Association (APPA) Edison Electric Institute (EEI) National Association of Regulatory Utility Commissioners (NARUC) National Rural Electric Cooperative Association (NRECA) Prepared by: Kenneth Rose and Karl Meeusen Preface This manual was prepared by Kenneth Rose, a consultant and Senior Fellow at the Institute of Public Utilities at Michigan State University, and Karl Meeusen,

  1. Benchmarking for electric utilities, tree trimming benchmarking, service line installation to single family residence, and distribution revenue meter testing and repair

    SciTech Connect (OSTI)

    Harder, J.

    1994-12-31

    An American Public Power Association (APPA) task force study on benchmarking for electric utilities is presented. Benchmark studies were made of three activities: (1) Tree trimming; (2) Service line installation to single family residence; (3) Distribution revenue meter testing and repair criteria. The results of the study areas are summarized for 15 utilities. The methodologies used for data collection and analysis are discussed. 28 figs., 9 tabs.

  2. Microsoft Word - NAP Coalition Response to DOE RFI DRAFT 10.11.01.docx

    Energy Savers [EERE]

    NAP Coalition Response to DOE RFI Addressing Policy and Logistical Challenges to Smart Grid Implementation November 1, 2010 The NAP Coalition is a "Coalition of Coalitions" that has been formed for the purpose of implementing the National Action Plan released by FERC in cooperation with DOE in June of 2010. Organizations working together on NAP implementation in include EEI, APPA, NRECA, ASE, ACEEE, NASUCA, NARUC, NASEO, DRSG, DRCC and EDF. The NAP Coalition submits a response in this

  3. NBP RFI: Communications Requirements - Reply Comments of Utilities Telecom

    Energy Savers [EERE]

    Council | Department of Energy Requirements - Reply Comments of Utilities Telecom Council NBP RFI: Communications Requirements - Reply Comments of Utilities Telecom Council The Utilities Telecom Council hereby files its reply comments in response to the Department of Energy (DOE) request for information on the communications needs of electric utilities and other such critical infrastructure industries (CII). The comments on the record- including those by APPA, EEI and NRECA, as well as API -

  4. Building Re-tuning Training | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Re-tuning Training Building Re-tuning Training Lead Performer: Pacific Northwest National Laboratory (PNNL) - Richland, WA Partners: -- Building Owners and Managers Association (BOMA) -- APPA: Leadership in Educational Facilities -- Pennsylvania State University - Philadelphia, PA FY16 DOE Funding: $25,000 Project Term: October 1, 2011 - September 30, 2016 Funding Type: Direct Lab Funding Project Website: https://www4.eere.energy.gov/workforce/projects/buildings-retuning-training PROJECT

  5. SSRLUO 2002 Executive Committee Members | Stanford Synchrotron...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Pingitore University of Texas at El Paso Environmental & Geosciences El Paso, TX 79968-0555 Phone: 915-747-5754 Fax: 915-747-5073 E-mail: nick@geo.utep.edu MACROMOLECULAR...

  6. BPA-2010-01236-FOIA Correspondence

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of all emails created by BPA employee Nick Peck relating to the subject of the Teanaway Solar Reserve from December 1, 2009, until the present. In addition, please include any...

  7. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    ... Liu, Jin-huan (4) Chen, Qiang (2) Shimaoka, Motomu (2) Springer, Timothy A. (2) Zhang, ... Liu, Jin-Huan (1) Pullen, Nick (1) Schrpf, Thomas (1) Springer, Timothy (1) Sun, Xiaqin ...

  8. Truman's decision to drop the bomb to be discussed at 70th anniversary...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and why he made it Contact Nick Njegomir Communications Office (505) 667-5679 Email "Harry S. Truman considered the use of the atomic bomb on Japan among the most important and...

  9. NERSC Update 2014-02-06.pptx

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Jay S rinivasan Computa4onal S ystems Richard G erber User Services Nick W right Advanced T ech Sheryas C holia Data & A naly4cs David S kinner Strategic Partnerships User ...

  10. NERSC_Workload_Analysis_v3.pptx

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Brian Austin, Tina Butler, Richard Gerber, Cary Whitney, Nick Wright, Woo-Sun Yang, Zhengji Zhao NERSC Workload Analysis on Hopper --- 1 --- February 2 2, 2 013 Understanding the...

  11. Tank Waste Committee Page 1

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... He said Nick Ceto in particular and DOE were concerned about the budget and asked the Board to pursue ... original low-activity glass described in the 2001 Performance Assessment. ...

  12. "Title","Creator/Author","Publication Date","OSTI Identifier...

    Office of Scientific and Technical Information (OSTI)

    Deep Bed Adsorption Testing using Silver-Functionalized Aerogel","Nick Soelberg; Tony Watson","2012-06-01T04:00:00Z",1062194,"10.21721062194","INLEXT-12-26522","DE-AC07-05ID14517...

  13. Harold Cofer and the COLEX process, part 4 ? Changes to support...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Nick about holding the speed record going from inside Alpha 4 or Alpha 5 to the cooling tower areas. He always wore high top galoshes, especially in Alpha 5 since there was...

  14. Microsoft Word - Climate-Infrastructure-Workshop_agenda_R4.docx

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Wolfram T-4: Misha Chertkov T-5: David Moulton, Aric Hagberg T-6: Nick Hengartner ESC: David Morris ADCLES: Nan Sauer ADTIR: NJ Nicholas ADTSC: John Sarrao, Paul Dotson...

  15. Reviving Algae from the (Almost) Dead - News Feature | NREL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Reviving Algae from the (Almost) Dead October 31, 2014 Photo of a man in a lab coat standing next to green algae bubbling in containers. NREL Research Technician Nick Sweeney...

  16. Recent content in 2014 Geothermal Case Study Challenge | OpenEI...

    Open Energy Info (EERE)

    07:41 Question For various reasons, you may w... NickL 6 May 2014 - 07:47 Answer Travis Brown and Kamran Baksh, Final Submission CSM 14 May 2014 - 21:59 Document Groups Menu You...

  17. Ceph: An Open Source Object Store Evan Harvey Gustavo Rayos

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Ceph: An Open Source Object Store Evan Harvey Gustavo Rayos Nick Schuchhardt Mentors: David Bonnie, Chris Hoffman, Dominic Manno LA---UR---15---25907 What is an Object Store? *...

  18. SSRLUOEC Minutes 2/03

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Anneli Munkholm, Erik Nelson, Piero Pianetta, Nick Pingitore, Tom Rabedeau, Deanne Jackson Rudd Uwe Bergmann, SSRLUO-EC Chair, called the meeting to order at 9:30 am. In...

  19. Green Button Applications | OpenEI Community

    Open Energy Info (EERE)

    Type Term Title Author Replies Last Post sort icon Blog entry contest DOE Leading by Example with Green Button, American Energy Data Challenge contest 4 NickL 5 May 2015 - 15:37...

  20. Green Button Applications | OpenEI Community

    Open Energy Info (EERE)

    Last Post sort icon Blog entry Green Button DOE Leading by Example with Green Button, American Energy Data Challenge contest 4 NickL 5 May 2015 - 15:37 Blog entry Green Button The...

  1. Data Challenge | OpenEI Community

    Open Energy Info (EERE)

    NickL(137) Contributor 5 May, 2015 - 15:37 DOE Leading by Example with Green Button, American Energy Data Challenge contest 4 contest Data Challenge Green Button DOE will launch...

  2. contest | OpenEI Community

    Open Energy Info (EERE)

    NickL(137) Contributor 5 May, 2015 - 15:37 DOE Leading by Example with Green Button, American Energy Data Challenge contest 4 contest Data Challenge Green Button DOE will launch...

  3. Green Button Applications | OpenEI Community

    Open Energy Info (EERE)

    Term Title Author Replies Last Post sort icon Blog entry Data Challenge DOE Leading by Example with Green Button, American Energy Data Challenge contest 4 NickL 5 May 2015 - 15:37...

  4. This list does not imply DOE endorsement of the individuals or...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... 503-579-8984 OR Simon, Tony simont@energy.wsu.edu 360-956-2141 OR Skupien, Nick NSS@Brabazon.com 920-883-7071 WI Smith, Ben benjamin.smith@cp.com 803-817-7128 SC ...

  5. Present and Future Computing Requirements

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Cosmology SciDAC-3 Project Ann Almgren (LBNL) Nick Gnedin (FNAL) Dave Higdon (LANL) Rob Ross (ANL) Martin White (UC Berkeley LBNL) Large Scale Production Computing and Storage...

  6. Statement from Energy Secretary Samuel W. Bodman on the Introduction...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    May 21, 2007 - 1:24pm Addthis "I commend Senator Thad Cochran and Congressmen Ralph Hall, Joe Barton, Nick Lampson, and Chip Pickering for introducing legislation today to increase ...

  7. SREL Reprint #3214

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    francisci) Laura V. Milko1, Nick M. Haddad1, and Stacey L. Lance2 1Department of Biology, North Carolina State University, Raleigh, NC 27695, USA 2Savannah River Ecology...

  8. Recent content in Water Power Forum | OpenEI Community

    Open Energy Info (EERE)

    - 11:43 Question 2013 projects and funding Vanessa.gregory 13 Dec 2013 - 09:12 Question Hi Vanessa-I connected wit... NickL 13 Dec 2013 - 14:38 Answer Worldwide 'Power exchanges'...

  9. Recent content in Geospatial | OpenEI Community

    Open Energy Info (EERE)

    - 21:45 Discussion Question about Map of Wind Farms Wzeng 13 Jul 2012 - 13:59 Question Hi, there is a button labeled ... NickL 13 Jul 2012 - 14:21 Answer How can I open .ASC...

  10. New page curation tool | OpenEI Community

    Open Energy Info (EERE)

    links may help you to Posted: 21 Jun 2013 - 14:37 by: NickL Dbrodt Another idea Posted: 22 May 2013 - 08:23 by: Dbrodt Rmckeel Show preview has been removed from utility rate...

  11. SANDIA REPORT SAND96-2031 UC-742 Unlimited Release

    Office of Scientific and Technical Information (OSTI)

    ... Attn: Nick Whitehead P.O. Box 4587 Houston, TX 77210-4587 Joseph Backofen P.O. Box 1925 Washington, D.C. 20013 1 -. 3distic Research Laboratory - Attn: J:T. Harrison R. Jameson . ...

  12. OpenEI Community - bug

    Open Energy Info (EERE)

    Ghost" entries http:en.openei.orgcommunitydiscussionghost-entries

    There is an issue that Illinois State University has come across.  From Nick B:

  13. University of Alaska Fairbanks | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Alaska Fairbanks University of Alaska Fairbanks From left to right: Shannan Hoyos, Ed Greene, Matthew Staley, Patrick Wade, Nick Janssen, Chic O'Dell, Pryce Brown, Bruce Lee, Wyatt Rehder, Dominic Dionne. Photo from the University of Alaska, Fairbanks. From left to right: Shannan Hoyos, Ed Greene, Matthew Staley, Patrick Wade, Nick Janssen, Chic O'Dell, Pryce Brown, Bruce Lee, Wyatt Rehder, Dominic Dionne. Photo from the University of Alaska, Fairbanks. Project Description For the inaugural U.S.

  14. Nicholas J. Nagle | Bioenergy | NREL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Nicholas J. Nagle Nicholas J. Nagle Bioprocessing Engineer Nick.Nagle@nrel.gov | 303-384-6184 Research Interests Nick is interested in understanding how advanced feedstocks perform in a biorefinery setting, assessing their physical and chemical properties, sugar release, and impact on lignin upgrading post conversion. As feedstocks rapidly evolve into new formats, such as densified and blended materials, he finds that evaluating the impact on the bioconversion processes, fermentation, and

  15. University of Maine Researching Floating Technologies for Deepwater

    Energy Savers [EERE]

    From left to right: Shannan Hoyos, Ed Greene, Matthew Staley, Patrick Wade, Nick Janssen, Chic O'Dell, Pryce Brown, Bruce Lee, Wyatt Rehder, Dominic Dionne. Photo from the University of Alaska, Fairbanks. From left to right: Shannan Hoyos, Ed Greene, Matthew Staley, Patrick Wade, Nick Janssen, Chic O'Dell, Pryce Brown, Bruce Lee, Wyatt Rehder, Dominic Dionne. Photo from the University of Alaska, Fairbanks. Project Description For the inaugural U.S. Department of Energy Collegiate Wind

  16. Evolutionary theory, web-search technology combine for DNA analysis

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Sequedex: bioinformatics breakthrough Evolutionary theory, web-search technology combine for DNA analysis Sequedex: bioinformatics breakthrough with clinical & environmental applications. October 4, 2012 From left, Los Alamos scientists Joel Berendzen, Ben McMahon, Mira Dimitrijevic, Nick Hengartner and Judith Cohn From left, Los Alamos scientists Joel Berendzen, Ben McMahon, Mira Dimitrijevic, Nick Hengartner and Judith Cohn Contact Nancy Ambrosiano Communications Office (505) 667-0471

  17. Final DOE Areas Feasibility Study, Appendices A - F

    Office of Legacy Management (LM)

    DOE Areas Feasibility Study Appendices LEHR CERCLA Completion Rev. 0 03/07/08 J:\DOE_STOLLER\4110\143\FEASIBILITY_STUDY\20080307_FS_TEXT_REV0.DOC WEISS ASSOCIATES Project Number: 130-4110-143 APPENDIX A COST ESTIMATES Final DOE Areas Feasibility Study Appendix A LEHR CERCLA Completion Rev. 0 03/07/08 Tables J:\DOE_Stoller\4110\143\Feasibility_Study\Rev0\Appendices\20080307_FS_APPA_tbls.doc Weiss Associates Project Number: 130-4110-143 Table A-1. Feasibility Study Cost Estimate Summaries Area/

  18. COMPLEAT (Community-Oriented Model for Planning Least-Cost Energy Alternatives and Technologies): A planning tool for publicly owned electric utilities. [Community-Oriented Model for Planning Least-Cost Energy Alternatives and Technologies (Compleat)

    SciTech Connect (OSTI)

    Not Available

    1990-09-01

    COMPLEAT takes its name, as an acronym, from Community-Oriented Model for Planning Least-Cost Energy Alternatives and Technologies. It is an electric utility planning model designed for use principally by publicly owned electric utilities and agencies serving such utilities. As a model, COMPLEAT is significantly more full-featured and complex than called out in APPA's original plan and proposal to DOE. The additional complexity grew out of a series of discussions early in the development schedule, in which it became clear to APPA staff and advisors that the simplicity characterizing the original plan, while highly desirable in terms of utility applications, was not achievable if practical utility problems were to be addressed. The project teams settled on Energy 20/20, an existing model developed by Dr. George Backus of Policy Assessment Associates, as the best candidate for the kinds of modifications and extensions that would be required. The remainder of the project effort was devoted to designing specific input data files, output files, and user screens and to writing and testing the compute programs that would properly implement the desired features around Energy 20/20 as a core program. This report presents in outline form, the features and user interface of COMPLEAT.

  19. Theoretical Biology and Biophysics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    6 Theoretical Biology and Biophysics Modeling biological systems and analysis and informatics of molecular and cellular biological data Mathematical Biology/Immunology Fundamental science and modeling enabling host-pathogen science Computational Structural Biology Understanding biomolecule function by determining their 3-D macromolecular structure Bioinformatics and Epidemiology Sequence analysis using advanced algorithms, software, computational hardware Contacts Group Leader Nick Hengartner

  20. Recent content in Green Button Applications | OpenEI Community

    Open Energy Info (EERE)

    Jun 2012 - 15:45 Blog entry OpenEI green button SDK Vgarud 5 Feb 2013 - 11:17 Question Hi Vivek-

    I reached... NickL 8 Feb 2013 - 14:03 Answer Probably the best reference...

  1. QER- Comment of American Public Power Association 5

    Broader source: Energy.gov [DOE]

    Attached are several documents for consideration for the QER Public Meeting: Electricity Transmission, Storage and Distribution in the West – APPA’s statement on the meeting; APPA’s August 2012, comments to the Department of Energy and Western Area Power Administration’s Joint Operations Team (JOT) on the JOT workshops held following the release of the March 2012, Memorandum from then-Secretary Chu to the PMAs; a January 31, 2014, letter from APPA and the National Rural Electric Cooperative Association (NRECA) to Secretary Moniz expressing concerns about recommendations made pertaining to the PMAs and the Tennessee Valley Authority in a report by the Center for a New Energy Economy; and Secretary Moniz’s response to the January 31, letter. These documents are being submitted herein to demonstrate the importance of recognizing and preserving the fundamental functions and mission of the PMAs. Thank you in advance for your consideration of these documents.

  2. Designing Targets for Elective Nodal Irradiation in Lung Cancer Radiotherapy: A Planning Study

    SciTech Connect (OSTI)

    Kepka, Lucyna; Tatro, Daniel; Moran, Jean M.; Quint, Leslie E.; Hayman, James A.; Ten Haken, Randall K.; Kong Fengming

    2009-04-01

    Purpose: To assess doses received by mediastinal and hilar lymph node stations (LNS) delineated according to published recommendations when 'standard' two-dimensional (2D) elective fields are applied and to assess doses to critical structures when fields are designed using 2D and three-dimensional (3D) treatment planning for elective irradiation. Methods and Materials: LNS were delineated on axial CT scans according to existing recommendations. For each case and tumor location, 2D anteroposterior-posteroanterior (AP-PA) elective fields were applied using the AP-PA CT topograms. From the 2D portal fields, 3D dose distributions were then calculated to particular LNS. Next, 3D plans were prepared for elective nodal irradiation for tumors of different lobes. Doses for critical structures were compared for 2D and 3D plans. Results: LNS 1/2R, 1/2L, 3A, 3P, 5, 6, and 8 were not adequately covered in a substantial part of plans by standard 2D portals when guidelines for delineation were strictly followed. The magnitude of the lack of coverage increased with margin application. There was a trend for a higher yet probably still safe dose delivered to lung for 3D plans compared with 2D plans with a prescription dose of 45 Gy. Conclusions: 2D fields did not entirely cover LNS delineated according to the recommendations for 3D techniques. A strict adherence to these guidelines may lead to larger portals than traditionally constructed using 2D methods. Some modifications for clinical implementation are discussed.

  3. Establishment of the United States Navy Mine Warfare Center of Excellence in the Corpus Christi Bay Area, Texas

    SciTech Connect (OSTI)

    Kosclski, J.L.; Boyer, R.; Sloger, W.

    1997-08-01

    The proposed establishment of the US Navy Mine Warfare Center of Excellence (MWCE) in the Corpus Christi Bay Area, Texas, involved the collocation of the Navy`s Mine Warfare and Mine Counter Measures assets in proximity to each other at Naval Station (NAVSTA) Ingleside and Naval Air Station (NAS) Corpus Christi, Texas. Collocation of these Navy forces would provide significant advantages in meeting mission and operational requirements. This action would improve the operational training and readiness of the forces. In addition to new construction or modifications at NAVSTA Ingleside, NAS Corpus Christi, and off-base; the establishment of offshore training and operating areas was required. When the project was first proposed in 1993, considerable concern was expressed by environmental interests, shrimpers, and state and federal resource agencies regarding the impact of the proposed training activities within Gulf waters. The Navy and Turner Collie and Braden, Inc., under contract to the Navy, conducted several technical studies and extensive coordination with concerned interests during the environmental impact statement process to identify and document the potential intensity, magnitude, and duration of impact from each proposed training activity.

  4. NERSC Signs Supercomputing Agreement with Cray

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Signs Supercomputing Agreement with Cray NERSC Signs Supercomputing Agreement with Cray June 27, 2012 NERSC Contact: Linda Vu, lvu@lbl.gov, +1 510 495 2402 Cray Media: Nick Davis pr@cray.com +1 206 701 2123 The Department of Energy's National Energy Research Scientific Computing Center (NERSC) announced today that Cray will install its next-generation supercomputer computing system. Consisting of products and services, the multi-year, multi-phase project is valued at more than $40 million. It

  5. NNSA Provides Training to Emergency Responders in Mexico | National Nuclear

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Materials | National Nuclear Security Administration Provides Tajikistan Specialized Vehicles to Transport Radiological Materials October 07, 2015 NNSA Program Manager Nick Cavellero, right, and NRSA Director of the Department of Information and International Relations Ilkhom Mirsaidov, left, with two specialized vehicles purchased by NNSA for Tajikistan. WASHINGTON - The Department of Energy's National Nuclear Security Administration (DOE/NNSA), the United States Embassy of Tajikistan, and

  6. III-V/Si Wafer Bonding Using Transparent, Conductive Oxide Interlayers;

    Office of Scientific and Technical Information (OSTI)

    Article No. 263904 (Journal Article) | SciTech Connect III-V/Si Wafer Bonding Using Transparent, Conductive Oxide Interlayers; Article No. 263904 Citation Details In-Document Search Title: III-V/Si Wafer Bonding Using Transparent, Conductive Oxide Interlayers; Article No. 263904 Authors: Tamboli, Adele C. ; van Hest, Maikel F. A. M. ; Steiner, Myles A. ; Essig, Stephanie ; Perl, Emmett E. ; Norman, Andrew G. ; Bosco, Nick ; Stradins, Paul Publication Date: 2015-06-29 OSTI Identifier: 1220722

  7. altd_manual

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Automatic L ibrary T racking D atabase Mark F ahey Nick J ones Bilel H adri Blake H itchcock Much o f t his m anual a ppears i n t he 2 010 C ray U ser G roup P roceedings p aper w ith t he s ame t itle b y Mark F ahey. June 2 010 Table o f C ontents Automatic L ibrary T racking D atabase ..................................................................................... 1 Abstract .

  8. Ten Problems

    Office of Scientific and Technical Information (OSTI)

    Ten Problems in Experimental Mathematics David H. Bailey ∗ , Jonathan M. Borwein † , Vishaal Kapoor ‡ and Eric Weisstein § September 21, 2004 Introduction This article was stimulated by the recent SIAM "100 Digit Challenge" of Nick Trefethen, beautifully described in [12]. Indeed, these ten numeric challenge problems are also listed in [14], where they are followed by the ten symbolic/numeric challenge problems that are discussed in this article. Our intent was to present ten

  9. Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin

    Office of Scientific and Technical Information (OSTI)

    Receptor Binding Site (Journal Article) | SciTech Connect Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding Site Citation Details In-Document Search Title: Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding Site Authors: Hong, Minsun ; Lee, Peter S. ; Hoffman, Ryan M.B. ; Zhu, Xueyong ; Krause, Jens C. ; Laursen, Nick S. ; Yoon, Sung-il ; Song, Langzhou ; Tussey, Lynda ; Crowe, Jr., James E. ; Ward, Andrew B. ;

  10. NREL: Performance and Reliability R&D - Photovoltaic Reliability

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Publications Photovoltaic Reliability Publications Sign up for NREL PV Reliability and Performance updates today! NREL publishes photovoltaic (PV) reliability journal articles, technical reports, conference papers, and outreach documents. Explore a sampling of our most recent or often-cited publications on PV reliability topics. The following NREL publications can be found on the following topics by clicking on the names of the researchers below. Accelerated Testing and Failure Analysis Nick

  11. NREL: Dynamic Maps, GIS Data, and Analysis Tools - Geospatial Team

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Geospatial Data Science Team The following are members of NREL's Geospatial Data Science Team: Jon Duckworth Michael Gleason Nick Grue Pamela Gray-Hann Donna Heimiller Dylan Hettinger Jim Leyshon Anthony Lopez Galen Maclaurin Meghan Mooney Billy J. Roberts If you have questions about our programs or would like to contact our staff, please email Webmaster. Printable Version NREL GIS Home About NREL GIS Renewable Energy Technical Potential Renewable Energy Economic Potential Maps Data Resources

  12. gms | National Nuclear Security Administration

    National Nuclear Security Administration (NNSA)

    gms NNSA Co-Hosts Nuclear Security Summit Workshop on Maritime Security with UK WASHINGTON - This week, the Department of Energy's National Nuclear Security Administration (DOE/NNSA) and the U.K. Department of Energy and Climate Change concluded a workshop at Wilton Park, United Kingdom, on the growing challenge of securing the global maritime supply chain. In... NNSA Provides Tajikistan Specialized Vehicles to Transport Radiological Materials NNSA Program Manager Nick Cavellero, right, and NRSA

  13. Participants

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Participants Participants Large Scale Computing and Storage Requirements for Basic Energy Sciences A DOE Technical Program Review October 8-9, 2013 Front row, from left: Yun Liu, Dave Goodwin, Eliane Lessner, Jack Deslippe, Nick Woodward, Carl Steefel, Ceren Susut, Katie Antypas, Richard Gerber. Back row, from left: Scott French, Jeff Neaton, Sudip Dosanjh, Harvey Wasserman, Jim Davenport, David Skinner, Andy Felmy, Jacqueline Chen, Sotiris Xantheas, Greg Newman, Mark Pederson. Organizers and

  14. Participants

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Participants Participants Large Scale Computing and Storage Requirements for Basic Energy Sciences An ASCR / BES / NERSC Workshop February 9-10, 2010 Name Organization Area James Davenport DOE/BES & Brookhaven National Lab Materials Sciences and Engineering Division; Theoretical Condensed Matter Physics Mark Pederson DOE/BES Chemical Sciences, Geosciences, and Biosciences Division; Computational and Theoretical Chemistry Nick Woodward DOE/BES Chemical Sciences, Geosciences, and Biosciences

  15. STAY CONNECTED: In This Issue Electricity Infrastructure

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    STAY CONNECTED: In This Issue Electricity Infrastructure Energy Efficiency and Renewable Energy Environmental Health and Remediation Clean Fossil Energy Nuclear News See how we were featured in the news, and read our press releases. Staff Accomplishments Nick Barilo Received Annual Merit Award from the DOE Hydrogen and Fuel August 2015 Renewable Fuel Options, Fish Tags, and Energy Forecasts: A Few of R&D Magazine's Favorite Things R&D Magazine announced their finalists for the 2015

  16. Presentations from the 12th Annual Small Business Conference, May 2011 |

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Department of Energy Presentations from the 12th Annual Small Business Conference, May 2011 Presentations from the 12th Annual Small Business Conference, May 2011 Please find the speaker presentations for the 12th Annual DOE Small Business Conference & Expo below. All presentations are in .pdf format. HOW TO DO BUSINESS WITH DOE 101 Nick Demer, Senior Procurement Analyst, Office of Small and Disadvantaged Business Utilization, U.S. Department of Energy Gary Lyttek, Business Source

  17. Green Button: Enabling Energy Innovation | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Button: Enabling Energy Innovation Green Button: Enabling Energy Innovation May 9, 2013 - 2:35pm Addthis Monisha Shah White House Council on Environmental Quality Nick Sinai U.S. Deputy Chief Technology Officer, White House Office of Science and Technology Policy What does this mean for me? Households and businesses can more easily use web and smartphone apps to pick the best rate plan for them. Consumers can take advantage of customized energy efficiency tips for their homes and businesses.

  18. Renewable Fuels from Algae Boosted by NREL Refinery Process - News Releases

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    | NREL Renewable Fuels from Algae Boosted by NREL Refinery Process February 9, 2016 A new biorefinery process developed by scientists at the Energy Department's National Renewable Energy Laboratory (NREL) has proven to be significantly more effective at producing ethanol from algae than previous research. The process, dubbed Combined Algal Processing (CAP), is detailed in a new paper by NREL's Tao Dong, Eric Knoshaug, Ryan Davis, Lieve Laurens, Stefanie Van Wychen, Philip Pienkos, and Nick

  19. Slide 1

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Business Opportunity Session Presenter: Nick Demer Senior Procurement Analyst September 24, 2009 Office of Small & Disadvantaged Business Utilization DOE Business Model Site and Facility Management Contractors (FMCs) Management and Operating (M&O) Contracts (FAR 17.6) DOE owns land and facilities, contractor employs research, development, and production personnel; and manages facility. Limited Liability Corporations (LLC) - Only responsibility is to manage and operate specific facility

  20. Biosecurity and Health

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biosecurity and Health Biosecurity and Health Los Alamos scientists are developing science and technology designed to battle pathogens responsible for causing disease epidemics, and extreme cases, pandemics. Contact Us Kirsten McCabe Emerging Threats Program Manager Email Andrew Bradbury Bioscience Group Leader Email Nick Hengartner Theoretical Biology and Biophysics Group Leader Email Rebecca McDonald Communication Specialist Email Projects in this subject area are concerned with countering

  1. 2012-2013 Research Communications Program | MIT-Harvard Center for

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Excitonics 2-2013 Research Communications Program Dylan Gleb and Geoffrey - outreach project Participants: Gleb Akselrod Dylan Arias Jordan Chesin Daniel Congreve Dorthe Eisele Joey Goodknight Vitor Manfrinato Phil Reusswig Geoffrey Supran Nick Thompson Stephanie Valleau Shane Yost Nano-day Photos Project Photos Video: How Solar Panels Work by Shane Yost and Jordan Chesin Video: The Exciting World of Excitons by Stephanie Valleau and Dan Congreve Video: Electron-Beam Lithography Toward the

  2. Innovative imaging systems on the Wendelstein 7-X bring steady-state fusion

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    energy closer to reality Innovative imaging systems on the Wendelstein Innovative imaging systems on the Wendelstein 7-X bring steady-state fusion energy closer to reality Innovative new imaging systems designed at Los Alamos are helping physicists peer into the roiling world of superhot plasmas. January 27, 2016 Glen Wurden in the stellarator's vacuum vessel during camera installation in 2014. Glen Wurden in the stellarator's vacuum vessel during camera installation in 2014. Contact Nick

  3. Attendees

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Attendees Attendees Registered Attendees Sean Ahern Oak Ridge National Laboratory William Allcock Argonne National Laboratory Sasha Ames Lawrence Livermore National Laboratory Katie Antypas NERSC Stephen Bailey LBNL Robert Ballance Sandia National Laboratories Nick Balthaserr NERSC Ashley Barker Oak Ridge Leadership Computing Facility Blaise Barney LLNL Christopher Beggio Sandia National Laboratories Wes Bethel LBNL Laura Biven DOE Kristofer Bouchard LBNL Jeff Broughton NERSC Suren Byna LBNL

  4. Search for: All records | DOE PAGES

    Office of Scientific and Technical Information (OSTI)

    Bruno, Nick" Name Name ORCID Search Authors Type: All Accepted Manuscript Published Article Publisher's Accepted Manuscript Journal Name: Subject: Identifier Numbers: Research Org: Sponsoring Org: Publication Date: to Update Date: to Sort: Relevance (highest to lowest) Publication Date (newest first) Publication Date (oldest first) Close Clear All Find Switch to Detail View for this search DOE PAGES Search Results Page 1 of 1 Search for: All records 1 results for: All records

  5. Los Alamos scientists monitor Santa's magical journey

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Scientists monitor Santa's magical journey Los Alamos scientists monitor Santa's magical journey Los Alamos trackers will use state-of-the-art technology to mark the course taken by St. Nick and his eight tiny and highly efficient reindeer. December 21, 2011 Los Alamos National Laboratory sits on top of a once-remote mesa in northern New Mexico with the Jemez mountains as a backdrop to research and innovation covering multi-disciplines from bioscience, sustainable energy sources, to plasma

  6. Lab scientists track Santa's magical journey

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Santa's magical journey Lab scientists track Santa's magical journey Los Alamos trackers will use state-of-the-art technology to mark the course taken by Old St. Nick and his reindeer. December 20, 2010 Los Alamos National Laboratory sits on top of a once-remote mesa in northern New Mexico with the Jemez mountains as a backdrop to research and innovation covering multi-disciplines from bioscience, sustainable energy sources, to plasma physics and new materials. Los Alamos National Laboratory

  7. Los Alamos names Laboratory Fellows for 2015

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Los Alamos names Laboratory Fellows for 2015 Los Alamos names Laboratory Fellows for 2015 The honorees are Michael Bernardin, Avadh Saxena, Carlos Tome and Piotr Zelenay. January 27, 2016 Piotr Zelenay, Carlos Tome, Michael Bernardin and Avadh Saxena Piotr Zelenay, Carlos Tome, Michael Bernardin and Avadh Saxena Contact Nick Njegomir Communications Office (505) 665-9394 Email "The Laboratory Fellows Organization recognizes researchers for innovative scientific and technical advances in

  8. Los Alamos scientist receives prestigious fellowship

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Los Alamos scientist receives prestigious fellowship Los Alamos scientist receives prestigious fellowship The American Association for the Advancement of Science (AAAS) has awarded the distinction of Fellow to Dave Morris. January 11, 2016 Dave Morris Dave Morris Contact Nick Njegomir Communications Office (505) 665-9394 Email "The AAAS fellowship is a great honor that recognizes Dave's prominence as a chemistry researcher and a scientific leader," said Carol Burns, Deputy Principal

  9. Los Alamos' Terwilliger named American Crystallographic Association

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    president Terwilliger named American Crystallographic Association president Los Alamos' Terwilliger named American Crystallographic Association president The ACA is the home to more than 1,000 scientists around the country who use X-rays, neutrons and electrons to see the shapes of molecules. April 27, 2016 Tom Terwilliger Tom Terwilliger Contact Nick Njegomir Communications Office (505) 665-9394 Email "This is an exciting time for crystallography because there are new ways to look at

  10. NNSA Provides Tajikistan Specialized Vehicles to Transport Radiological

    National Nuclear Security Administration (NNSA)

    Materials | National Nuclear Security Administration Library / Press Releases NNSA Provides Tajikistan Specialized Vehicles to Transport Radiological Materials October 07, 2015 NNSA Program Manager Nick Cavellero, right, and NRSA Director of the Department of Information and International Relations Ilkhom Mirsaidov, left, with two specialized vehicles purchased by NNSA for Tajikistan. WASHINGTON - The Department of Energy's National Nuclear Security Administration (DOE/NNSA), the United

  11. Student Spotlight

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Czapla Nick Czapla Project Name: Image Analysis Classification algorithm to automatically classify NIF optics damage sites Project Description: Develop a classification system of potential damage sites on the NIF Final Optics based on the sites' morphology (i.e., shape, color, size, roughness of edges, etc.) and automate the classification process using a wavelet transformation algorithm, called the Image Analysis Classification (IAC), written by Wim deVries. The project includes the manual

  12. Cosmic Reionization On Computers | Argonne Leadership Computing Facility

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Simulation of cosmic reionization Simulation of cosmic reionization. Dark red shows opaque neutral gas, transparent blue is ionized gas, and yellow dots are galaxies. Nick Gnedin, Fermilab Cosmic Reionization On Computers PI Name: Nickolay Gnedin PI Email: gnedin@fnal.gov Institution: Fermilab Allocation Program: INCITE Allocation Hours at ALCF: 65 Million Year: 2016 Research Domain: Physics Cosmic reionization, the most recent phase transition in the history of the universe, is the process by

  13. Cost and Performance Assumptions for Modeling Electricity Generation Technologies

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Cost and Performance Assumptions for Modeling Electricity Generation Technologies Rick Tidball, Joel Bluestein, Nick Rodriguez, and Stu Knoke ICF International Fairfax, Virginia Subcontract Report NREL/SR-6A20-48595 November 2010 NREL is a national laboratory of the U.S. Department of Energy, Office of Energy Efficiency & Renewable Energy, operated by the Alliance for Sustainable Energy, LLC. National Renewable Energy Laboratory 1617 Cole Boulevard Golden, Colorado 80401 303-275-3000 *

  14. Business Opportunity Session Materials | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Business Opportunity Session Materials Business Opportunity Session Materials Presentations from our Washington DC Business Opportunity Session, held March 3, 2011 How to do Business with DOE Nickolas (Nick) Demer Senior Procurement Analyst OSDBU NNSA Opportunities Gary Lyttek Small Business Program Manager, NNSA Sandia National Laboratories Opportunities Don Devoti, Small Business Program Manager, Sandia National Laboratories Office of Science SBIR/STTR, Chris O'Gwin, Program Analyst, SBIR/STTR

  15. At Plasma Camp, teachers experience research front and center | Princeton

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Plasma Physics Lab At Plasma Camp, teachers experience research front and center By Constance Kaita August 12, 2013 Tweet Widget Google Plus One Share on Facebook Wendy Dlakic, a physics and earth science teacher from Livingston, Mont., examines a plasma with Nick Guilbert, a master teacher and collaborator from The Peddie School, at this year's Plasma Camp for physics teachers at PPPL from July 15 to 19. (Photo by Photo by Elle Starkman/ PPPL Office of Communications) Wendy Dlakic, a

  16. Method for introducing unidirectional nested deletions

    DOE Patents [OSTI]

    Dunn, J.J.; Quesada, M.A.; Randesi, M.

    1999-07-27

    Disclosed is a method for the introduction of unidirectional deletions in a cloned DNA segment. More specifically, the method comprises providing a recombinant DNA construct comprising a DNA segment of interest inserted in a cloning vector. The cloning vector has an f1 endonuclease recognition sequence adjacent to the insertion site of the DNA segment of interest. The recombinant DNA construct is then contacted with the protein pII encoded by gene II of phage f1 thereby generating a single-stranded nick. The nicked DNA is then contacted with E. coli Exonuclease III thereby expanding the single-stranded nick into a single-stranded gap. The single-stranded gapped DNA is then contacted with a single-strand-specific endonuclease thereby producing a linearized DNA molecule containing a double-stranded deletion corresponding in size to the single-stranded gap. The DNA treated in this manner is then incubated with DNA ligase under conditions appropriate for ligation. Also disclosed is a method for producing single-stranded DNA probes. In this embodiment, single-stranded gapped DNA, produced as described above, is contacted with a DNA polymerase in the presence of labeled nucleotides to fill in the gap. This DNA is then linearized by digestion with a restriction enzyme which cuts outside the DNA segment of interest. The product of this digestion is then denatured to produce a labeled single-stranded nucleic acid probe. 1 fig.

  17. Method for producing labeled single-stranded nucleic acid probes

    DOE Patents [OSTI]

    Dunn, John J.; Quesada, Mark A.; Randesi, Matthew

    1999-10-19

    Disclosed is a method for the introduction of unidirectional deletions in a cloned DNA segment. More specifically, the method comprises providing a recombinant DNA construct comprising a DNA segment of interest inserted in a cloning vector, the cloning vector having an f1 endonuclease recognition sequence adjacent to the insertion site of the DNA segment of interest. The recombinant DNA construct is then contacted with the protein pII encoded by gene II of phage f1 thereby generating a single-stranded nick. The nicked DNA is then contacted with E. coli Exonuclease III thereby expanding the single-stranded nick into a single-stranded gap. The single-stranded gapped DNA is then contacted with a single-strand-specific endonuclease thereby producing a linearized DNA molecule containing a double-stranded deletion corresponding in size to the single-stranded gap. The DNA treated in this manner is then incubated with DNA ligase under conditions appropriate for ligation. Also disclosed is a method for producing single-stranded DNA probes. In this embodiment, single-stranded gapped DNA, produced as described above, is contacted with a DNA polymerase in the presence of labeled nucleotides to fill in the gap. This DNA is then linearized by digestion with a restriction enzyme which cuts outside the DNA segment of interest. The product of this digestion is then denatured to produce a labeled single-stranded nucleic acid probe.

  18. Method for introducing unidirectional nested deletions

    DOE Patents [OSTI]

    Dunn, John J.; Quesada, Mark A.; Randesi, Matthew

    1999-07-27

    Disclosed is a method for the introduction of unidirectional deletions in a cloned DNA segment. More specifically, the method comprises providing a recombinant DNA construct comprising a DNA segment of interest inserted in a cloning vector, the cloning vector having an f1 endonuclease recognition sequence adjacent to the insertion site of the DNA segment of interest. The recombinant DNA construct is then contacted with the protein pII encoded by gene II of phage f1 thereby generating a single-stranded nick. The nicked DNA is then contacted with E. coli Exonuclease III thereby expanding the single-stranded nick into a single-stranded gap. The single-stranded gapped DNA is then contacted with a single-strand-specific endonuclease thereby producing a linearized DNA molecule containing a double-stranded deletion corresponding in size to the single-stranded gap. The DNA treated in this manner is then incubated with DNA ligase under conditions appropriate for ligation. Also disclosed is a method for producing single-stranded DNA probes. In this embodiment, single-stranded gapped DNA, produced as described above, is contacted with a DNA polymerase in the presence of labeled nucleotides to fill in the gap. This DNA is then linearized by digestion with a restriction enzyme which cuts outside the DNA segment of interest. The product of this digestion is then denatured to produce a labeled single-stranded nucleic acid probe.

  19. Determining orientation and direction of DNA sequences

    DOE Patents [OSTI]

    Goodwin, Edwin H.; Meyne, Julianne

    2000-01-01

    Determining orientation and direction of DNA sequences. A method by which fluorescence in situ hybridization can be made strand specific is described. Cell cultures are grown in a medium containing a halogenated nucleotide. The analog is partially incorporated in one DNA strand of each chromatid. This substitution takes place in opposite strands of the two sister chromatids. After staining with the fluorescent DNA-binding dye Hoechst 33258, cells are exposed to long-wavelength ultraviolet light which results in numerous strand nicks. These nicks enable the substituted strand to be denatured and solubilized by heat, treatment with high or low pH aqueous solutions, or by immersing the strands in 2.times.SSC (0.3M NaCl+0.03M sodium citrate), to name three procedures. It is unnecessary to enzymatically digest the strands using Exo III or another exonuclease in order to excise and solubilize nucleotides starting at the sites of the nicks. The denaturing/solubilizing process removes most of the substituted strand while leaving the prereplication strand largely intact. Hybridization of a single-stranded probe of a tandem repeat arranged in a head-to-tail orientation will result in hybridization only to the chromatid with the complementary strand present.

  20. Truman's decision to drop the bomb to be discussed at 70th anniversary

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    lecture July 10 70th anniversary lecture July 10 about Truman, bomb Truman's decision to drop the bomb to be discussed at 70th anniversary lecture July 10 Noel Pugach will discuss Truman's decision to drop atomic bombs on Japanese cities and explain how and why he made it July 3, 2013 70th anniversary lecture July 10 about Truman, bomb Noel Pugach will discuss Truman's decision to drop atomic bombs on Japanese cities and explain how and why he made it Contact Nick Njegomir Communications

  1. 1

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    track Santa's magical journey December 20, 2010 LOS ALAMOS, New Mexico, December 20, 2010-For the 55th consecutive year, millions of people all over the world over will be able to keep tabs on Santa as he treks around the globe delivering presents to good girls and boys. And scientists from Los Alamos National Laboratory are again part of the effort! Los Alamos trackers will use state-of-the-art technology to mark the course taken by Old St. Nick and his reindeer; visit http://santa.lanl.gov

  2. Super Wi-Fi is Super for Energy Too | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Wi-Fi is Super for Energy Too Super Wi-Fi is Super for Energy Too September 24, 2010 - 11:45am Addthis Super Wi-Fi is Super for Energy Too Nick Sinai U.S. Deputy Chief Technology Officer, White House Office of Science and Technology Policy What does this mean for me? By integrating broadband into the emerging Smart Grid, consumers will have revolutionized communication with their utility -- they will have detailed information on their energy use that will help inform them how they can save on

  3. FY2002 SSRLUO Executive Committee

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    SSRL USERS' ORGANIZATION 2002 EXECUTIVE COMMITTEE ENVIRONMENTAL/GEOSCIENCES Satish Myneni Princeton University Geoscience 151 Guyot Hall Princeton, NJ 08544 Phone: 609-258-5848 E-mail: smyneni@princeton.edu Nicholas Pingitore University of Texas at El Paso Environmental & Geosciences El Paso, TX 79968-0555 Phone: 915-747-5754 Fax: 915-747-5073 E-mail: nick@geo.utep.edu MACROMOLECULAR CRYSTALLOGRAPHY Paul Foster(ex-officio) UCSF/Exelixis Biophysics Box 0448 San Francisco, CA 94143 Phone:

  4. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    Switch to Detail View for this search SciTech Connect Search Results Page 1 of 2 Search for: All records Creators/Authors contains: "Nick Soelberg" × Sort by Relevance Sort by Date (newest first) Sort by Date (oldest first) Sort by Relevance « Prev Select page number Go to page: 1 of 2 1 » Next » Everything18 Electronic Full Text16 Citations2 Multimedia0 Datasets0 Software0 Filter Results Filter by Subject mgmt of radioactive and non-radioactive wastes from nuclear facilities (7)

  5. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    Switch to Detail View for this search SciTech Connect Search Results Page 2 of 2 Search for: All records Creators/Authors contains: "Nick Soelberg" × Sort by Relevance Sort by Date (newest first) Sort by Date (oldest first) Sort by Relevance « Prev Select page number Go to page: 2 of 2 2 » Next » Everything18 Electronic Full Text16 Citations2 Multimedia0 Datasets0 Software0 Filter Results Filter by Subject mgmt of radioactive and non-radioactive wastes from nuclear facilities (7)

  6. Brainwaves as a Biometric Parameter for Unique Identification and

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Brainstorming Apps for a Clean Energy Future Brainstorming Apps for a Clean Energy Future July 20, 2012 - 1:03pm Addthis Notes from the July 9th Energy Data Jam in New York City | Credit: Openei.org Notes from the July 9th Energy Data Jam in New York City | Credit: Openei.org Nick Sinai U.S. Deputy Chief Technology Officer, White House Office of Science and Technology Policy Ian Kalin Director of the Energy Data Initiative How can I participate? You can contribute ideas for new products,

  7. New shared lab spells opportunity for small biotech start-ups

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    New shared lab spells opportunity for small biotech start-ups Community Connections: Your link to news and opportunities from Los Alamos National Laboratory Latest Issue:May 2016 all issues All Issues » submit New shared lab spells opportunity for small biotech start-ups Local innovation returns home May 5, 2014 BioScience Lab opens. (Left to right) New Mexico State Representative Jim Trujillo; U.S. Congressman Ben Ray Lujan; New Mexico State Representative Nick Salazar; U.S. Senator Tom Udall;

  8. Forming the Future

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    - - - - Automotive BY NICK WRIGHT, EXECUTIVE EDITOR A computer program generates a tool path for the robots based on a CAD design, turning 2 D sheet metal into a 3 D part. A blue grease is applied before the sheet is held into place with De sta co clamps. The grease protects the metal's surface finish during forming. Styluses above and below the sheet manipulate the metal into shape. FFJournal ® April 2014 As seen in the April 2014 issue of ® A bout 10 miles west of down- town Detroit sprawls

  9. Christmas Eve

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    to surveil Santa's sleigh Christmas Eve December 21, 2012 Efforts will help ensure Magical Elf's safe passage across the globe LOS ALAMOS, NEW MEXICO, Dec. 21, 2012-Los Alamos trackers will use state- of-the-art technology to mark the course taken this year by Santa Claus and his eight tiny reindeer during the Jolly Elf's annual mission to spread joy to all the children of the world. Visit http://santa.lanl.gov beginning at 6 a.m. December 24 to see St. Nick's whirlwind journey. December 21st

  10. Reviving Algae from the (Almost) Dead - News Feature | NREL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Reviving Algae from the (Almost) Dead October 31, 2014 Photo of a man in a lab coat standing next to green algae bubbling in containers. NREL Research Technician Nick Sweeney inoculates algae being grown in a tent reactor. Algae brought back to active states from cryogenic tanks need aerobic environments to meet their full potential as biofuels. Photo by Dennis Schroeder, NREL Tucked away in darkness and almost dead, algae can emerge from a frigid and foggy environment to live again-and perhaps

  11. Statement from Energy Secretary Samuel W. Bodman on the Introduction of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Legislation to Expand the SPR | Department of Energy the Introduction of Legislation to Expand the SPR Statement from Energy Secretary Samuel W. Bodman on the Introduction of Legislation to Expand the SPR May 21, 2007 - 1:24pm Addthis "I commend Senator Thad Cochran and Congressmen Ralph Hall, Joe Barton, Nick Lampson, and Chip Pickering for introducing legislation today to increase the capacity of the Strategic Petroleum Reserve to 1.5 billion barrels. This will further protect America

  12. Los Alamos' David Mascareñas receives Presidential Early Career Award

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Mascareñas receives Presidential Early Career Award Los Alamos' David Mascareñas receives Presidential Early Career Award David Mascareñas was named a recipient of the Presidential Early Career Award by President Obama last week. February 24, 2016 David Mascareñas David Mascareñas Contact Nick Njegomir Communications Office (505) 665-9394 Email "David is an innovative engineer whose creative thinking is essential to the continuing success of Los Alamos' national-security science

  13. Method for assaying clustered DNA damages

    DOE Patents [OSTI]

    Sutherland, Betsy M.

    2004-09-07

    Disclosed is a method for detecting and quantifying clustered damages in DNA. In this method, a first aliquot of the DNA to be tested for clustered damages with one or more lesion-specific cleaving reagents under conditions appropriate for cleavage of the DNA to produce single-strand nicks in the DNA at sites of damage lesions. The number average molecular length (Ln) of double stranded DNA is then quantitatively determined for the treated DNA. The number average molecular length (Ln) of double stranded DNA is also quantitatively determined for a second, untreated aliquot of the DNA. The frequency of clustered damages (.PHI..sub.c) in the DNA is then calculated.

  14. Student Spotlight

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Zobrist Nick Zobrist Junior (graduating spring 2015) Physics and Applied Mathematics, U.C. Berkeley, Area of NIF: Optics Inspection Tell us about your work at NIF. I'm here to contribute to the optics inspection algorithms that evaluate the condition of NIF's optics. One of the ways I've done this is by modeling reflection locations which is a new capability that they've needed, but I've helped my mentor, Laura Kegelmeyer, with parts of other projects as well. You received an award for your work

  15. Structure of an aprataxin?DNA complex with insights into AOA1 neurodegenerative disease

    SciTech Connect (OSTI)

    Tumbale, Percy; Appel, C. Denise; Kraehenbuehl, Rolf; Robertson, Patrick D.; Williams, Jessica S.; Krahn, Joe; Ahel, Ivan; Williams, R. Scott (NIEHS); (Manchester)

    2012-09-17

    DNA ligases finalize DNA replication and repair through DNA nick-sealing reactions that can abort to generate cytotoxic 5'-adenylation DNA damage. Aprataxin (Aptx) catalyzes direct reversal of 5'-adenylate adducts to protect genome integrity. Here the structure of a Schizosaccharomyces pombe Aptx-DNA-AMP-Zn{sup 2+} complex reveals active site and DNA interaction clefts formed by fusing a histidine triad (HIT) nucleotide hydrolase with a DNA minor groove-binding C{sub 2}HE zinc finger (Znf). An Aptx helical 'wedge' interrogates the base stack for sensing DNA ends or DNA nicks. The HIT-Znf, the wedge and an '[F/Y]PK' pivot motif cooperate to distort terminal DNA base-pairing and direct 5'-adenylate into the active site pocket. Structural and mutational data support a wedge-pivot-cut HIT-Znf catalytic mechanism for 5'-adenylate adduct recognition and removal and suggest that mutations affecting protein folding, the active site pocket and the pivot motif underlie Aptx dysfunction in the neurodegenerative disorder ataxia with oculomotor apraxia 1 (AOA1).

  16. Distinct kinetics of human DNA ligases I, IIIalpha, IIIbeta, and IV reveal direct DNA sensing ability and differential physiological functions in DNA repair

    SciTech Connect (OSTI)

    Chen, Xi; Ballin, Jeff D.; Della-Maria, Julie; Tsai, Miaw-Sheue; White, Elizabeth J.; Tomkinson, Alan E.; Wilson, Gerald M.

    2009-05-11

    The three human LIG genes encode polypeptides that catalyze phosphodiester bond formation during DNA replication, recombination and repair. While numerous studies have identified protein partners of the human DNA ligases (hLigs), there has been little characterization of the catalytic properties of these enzymes. In this study, we developed and optimized a fluorescence-based DNA ligation assay to characterize the activities of purified hLigs. Although hLigI joins DNA nicks, it has no detectable activity on linear duplex DNA substrates with short, cohesive single-strand ends. By contrast, hLigIII{beta} and the hLigIII{alpha}/XRCC1 and hLigIV/XRCC4 complexes are active on both nicked and linear duplex DNA substrates. Surprisingly, hLigIV/XRCC4, which is a key component of the major non-homologous end joining (NHEJ) pathway, is significantly less active than hLigIII on a linear duplex DNA substrate. Notably, hLigIV/XRCC4 molecules only catalyze a single ligation event in the absence or presence of ATP. The failure to catalyze subsequent ligation events reflects a defect in the enzyme-adenylation step of the next ligation reaction and suggests that, unless there is an in vivo mechanism to reactivate DNA ligase IV/XRCC4 following phosphodiester bond formation, the cellular NHEJ capacity will be determined by the number of adenylated DNA ligaseIV/XRCC4 molecules.

  17. Coal combustion waste management at landfills and surface impoundments 1994-2004.

    SciTech Connect (OSTI)

    Elcock, D.; Ranek, N. L.; Environmental Science Division

    2006-09-08

    On May 22, 2000, as required by Congress in its 1980 Amendments to the Resource Conservation and Recovery Act (RCRA), the U.S. Environmental Protection Agency (EPA) issued a Regulatory Determination on Wastes from the Combustion of Fossil Fuels. On the basis of information contained in its 1999 Report to Congress: Wastes from the Combustion of Fossil Fuels, the EPA concluded that coal combustion wastes (CCWs), also known as coal combustion by-products (CCBs), did not warrant regulation under Subtitle C of RCRA, and it retained the existing hazardous waste exemption for these materials under RCRA Section 3001(b)(3)(C). However, the EPA also determined that national regulations under Subtitle D of RCRA were warranted for CCWs that are disposed of in landfills or surface impoundments. The EPA made this determination in part on the basis of its findings that 'present disposal practices are such that, in 1995, these wastes were being managed in 40 percent to 70 percent of landfills and surface impoundments without reasonable controls in place, particularly in the area of groundwater monitoring; and while there have been substantive improvements in state regulatory programs, we have also identified gaps in State oversight' (EPA 2000). The 1999 Report to Congress (RTC), however, may not have reflected the changes in CCW disposal practices that occurred since the cutoff date (1995) of its database and subsequent developments. The U.S. Department of Energy (DOE) and the EPA discussed this issue and decided to conduct a joint DOE/EPA study to collect new information on the recent CCW management practices by the power industry. It was agreed that such information would provide a perspective on the chronological adoption of control measures in CCW units based on State regulations. A team of experts from the EPA, industry, and DOE (with support from Argonne National Laboratory) was established to develop a mutually acceptable approach for collecting and analyzing data on CCW disposal practices and State regulatory requirements at landfills and surface impoundments that were permitted, built, or laterally expanded between January 1, 1994, and December 31, 2004. The scope of the study excluded waste units that manage CCWs in active or abandoned coal mines. The EPA identified the following three areas of interest: (1) Recent and current CCW industry surface disposal management practices, (2) State regulatory requirements for CCW management, and (3) Implementation of State requirements (i.e., the extent to which States grant or deny operator requests to waive or vary regulatory requirements and the rationales for doing so). DOE and the EPA obtained data on recent and current disposal practices from a questionnaire that the Utility Solid Waste Activities Group (USWAG) distributed to its members that own or operate coal-fired power plants. USWAG, formed in 1978, is responsible for addressing solid and hazardous waste issues on behalf of the utility industry. It is an informal consortium of approximately 80 utility operating companies, the Edison Electric Institute (EEI), the National Rural Electric Cooperative Association (NRECA), the American Public Power Association (APPA), and the American Gas Association (AGA). EEI is the principal national association of investor-owned electric power and light companies. NRECA is the national association of rural electric cooperatives. APPA is the national association of publicly owned electric utilities. AGA is the national association of natural gas utilities. Together, USWAG member companies and trade associations represent more than 85% of the total electric generating capacity of the United States and service more than 95% of the nation's consumers of electricity. To verify the survey findings, the EPA also asked State regulators from nine selected States that are leading consumers of coal for electricity generation for information on disposal units that may not have been covered in the USWAG survey. The selected States were Georgia, Illinois, Indiana, Michigan, Missouri, North Carolina, North Da

  18. All Hands Program Review Off-site | MIT-Harvard Center for Excitonics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Review Off-site January 25, 2012 at 9am-7pm / MIT Endicott House IMG_4534 IMG_4500.02 IMG_4452 IMG_4410 (click images for a larger view) Time Presenter 8:30-9:00AM Continental Breakfast 9:00AM Opening remarks-Marc Baldo EFRC - Seeds 9:10AM Natalia Shustova 9:15AM David Ciudad 9:20AM YongJoo Kim 9:25AM Will Tisdale 9:30AM Q&A EFRC - 4 10:30-10:55AM Break EFRC - 3 10:55AM Priya Jadhav 11:00AM Phil Reusswig 11:05AM Jiye Lee 11:10AM Nick Thompson 11:15AM Paul Azunre 11:20AM Shane Yost 11:25AM

  19. Site directed recombination

    DOE Patents [OSTI]

    Jurka, Jerzy W.

    1997-01-01

    Enhanced homologous recombination is obtained by employing a consensus sequence which has been found to be associated with integration of repeat sequences, such as Alu and ID. The consensus sequence or sequence having a single transition mutation determines one site of a double break which allows for high efficiency of integration at the site. By introducing single or double stranded DNA having the consensus sequence flanking region joined to a sequence of interest, one can reproducibly direct integration of the sequence of interest at one or a limited number of sites. In this way, specific sites can be identified and homologous recombination achieved at the site by employing a second flanking sequence associated with a sequence proximal to the 3'-nick.

  20. Trichodermin induces cell apoptosis through mitochondrial dysfunction and endoplasmic reticulum stress in human chondrosarcoma cells

    SciTech Connect (OSTI)

    Su, Chen-Ming; Wang, Shih-Wei; Lee, Tzong-Huei; Tzeng, Wen-Pei; Hsiao, Che-Jen; Liu, Shih-Chia; Tang, Chih-Hsin

    2013-10-15

    Chondrosarcoma is the second most common primary bone tumor, and it responds poorly to both chemotherapy and radiation treatment. Nalanthamala psidii was described originally as Myxosporium in 1926. This is the first study to investigate the anti-tumor activity of trichodermin (trichothec-9-en-4-ol, 12,13-epoxy-, acetate), an endophytic fungal metabolite from N. psidii against human chondrosarcoma cells. We demonstrated that trichodermin induced cell apoptosis in human chondrosarcoma cell lines (JJ012 and SW1353 cells) instead of primary chondrocytes. In addition, trichodermin triggered endoplasmic reticulum (ER) stress protein levels of IRE1, p-PERK, GRP78, and GRP94, which were characterized by changes in cytosolic calcium levels. Furthermore, trichodermin induced the upregulation of Bax and Bid, the downregulation of Bcl-2, and the dysfunction of mitochondria, which released cytochrome c and activated caspase-3 in human chondrosarcoma. In addition, animal experiments illustrated reduced tumor volume, which led to an increased number of terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL)-positive cells and an increased level of cleaved PARP protein following trichodermin treatment. Together, this study demonstrates that trichodermin is a novel anti-tumor agent against human chondrosarcoma cells both in vitro and in vivo via mitochondrial dysfunction and ER stress. - Highlights: • Trichodermin induces chondrosarcoma apoptosis. • ER stress is involved in trichodermin-induced cell death. • Trichodermin induces chondrosarcoma death in vivo.

  1. Nuclear translocation and overexpression of GAPDH by the hyper-pressure in retinal ganglion cell

    SciTech Connect (OSTI)

    Kim, Choong-Il; Lee, Sung-Ho; Seong, Gong-Je; Kim, Yeon-Hyang; Lee, Mi-Young . E-mail: miyoung@sch.ac.kr

    2006-03-24

    To investigate the effect of hyper-pressure on retinal ganglion cells (RGC-5), RGC-5 cells were exposed to an ambient hydrostatic pressure of 100 mm Hg. Upon treatment, the proliferation of RGC-5 cells was inhibited and neuronal apoptosis was detected by specific apoptosis marker TUNEL (terminal deoxynucleotidyl transferase dUTP nick-end labeling). To probe into the mechanism mediating the apoptosis of RGC-5 cells in 100 mm Hg, protein profile alterations following hyper-pressure treatment were examined using two-dimensional gel electrophoresis (2-DE) followed by MALDI-TOF. Out of the 400 protein spots of RGC-5 cells detected on 2-DE gels, 37 differentially expressed protein spots were further identified using in gel tryptic digestion and mass spectrometry. Among these proteins, glyceraldehyde-3-phosphate-dehydrogenase (GAPDH) was significantly expressed 10 times more in 100 mm Hg than in normal pressure. The accumulation of GAPDH in the nucleus and its translocation from the cytosol to the nucleus in 100 mm Hg were observed using a microscope. These results suggest that the hyper-pressure-induced apoptosis in RGC-5 cells may be involved with not only the increase of GAPDH expression, but also the accumulation and the translocalization of GAPDH to the nucleus.

  2. Hydraulic and Clean-in-Place Evaluations for a 12.5-cm Annular Centrifugal Contactor at INL

    SciTech Connect (OSTI)

    Troy G. Garn; David H. Meikrantz; Nick R. Mann; Jack D. Law; Terry A. Todd

    2008-09-01

    Hydraulic and Clean-in-Place Evaluations for a 12.5 cm Annular Centrifugal Contactor at the INL Troy G. Garn, Dave H. Meikrantz, Nick R. Mann, Jack D. Law, Terry A. Todd Idaho National Laboratory Commercially available, Annular Centrifugal Contactors (ACC) are currently being evaluated for processing dissolved nuclear fuel solutions to selectively partition integrated elements using solvent extraction technologies. These evaluations include hydraulic and clean-in-place (CIP) testing of a commercially available 12.5 cm unit. Data from these evaluations is used to support design of future nuclear fuel reprocessing facilities. Hydraulic testing provides contactor throughput performance data on two-phase systems for a wide range of operating conditions. Hydraulic testing results on a simple two-phase oil and water system followed by a 30 % Tributyl phosphate in N-dodecane / nitric acid pair are reported. Maximum total throughputs for this size contactor ranged from 20 to 32 liters per minute without significant other phase carryover. A relatively new contactor design enhancement providing Clean-in-Place capability for ACCs was also investigated. Spray nozzles installed into the central rotor shaft allow the rotor internals to be cleaned, offline. Testing of the solids capture of a diatomaceous earth/water slurry feed followed by CIP testing was performed. Solids capture efficiencies of >95% were observed for all tests and short cold water cleaning pulses proved successful at removing solids from the rotor.

  3. Crystal Structure of the Phage T4 Recombinase UvsX and Its Functional Interaction with the T4 SF2 Helicase UvsW

    SciTech Connect (OSTI)

    Gajewski, Stefan; Webb, Michael R.; Galkin, Vitold; Egelman, Edward H.; Kreuzer, Kenneth N.; White, Stephen W.

    2012-07-11

    Bacteriophage T4 provides an important model system for studying the mechanism of homologous recombination. We have determined the crystal structure of the T4 UvsX recombinase, and the overall architecture and fold closely resemble those of RecA, including a highly conserved ATP binding site. Based on this new structure, we reanalyzed electron microscopy reconstructions of UvsX-DNA filaments and docked the UvsX crystal structure into two different filament forms: a compressed filament generated in the presence of ADP and an elongated filament generated in the presence of ATP and aluminum fluoride. In these reconstructions, the ATP binding site sits at the protomer interface, as in the RecA filament crystal structure. However, the environment of the ATP binding site is altered in the two filament reconstructions, suggesting that nucleotide cannot be as easily accommodated at the protomer interface of the compressed filament. Finally, we show that the phage helicase UvsW completes the UvsX-promoted strand-exchange reaction, allowing the generation of a simple nicked circular product rather than complex networks of partially exchanged substrates.

  4. Measurement Practices for Reliability and Power Quality

    SciTech Connect (OSTI)

    Kueck, JD

    2005-05-06

    This report provides a distribution reliability measurement ''toolkit'' that is intended to be an asset to regulators, utilities and power users. The metrics and standards discussed range from simple reliability, to power quality, to the new blend of reliability and power quality analysis that is now developing. This report was sponsored by the Office of Electric Transmission and Distribution, U.S. Department of Energy (DOE). Inconsistencies presently exist in commonly agreed-upon practices for measuring the reliability of the distribution systems. However, efforts are being made by a number of organizations to develop solutions. In addition, there is growing interest in methods or standards for measuring power quality, and in defining power quality levels that are acceptable to various industries or user groups. The problems and solutions vary widely among geographic areas and among large investor-owned utilities, rural cooperatives, and municipal utilities; but there is still a great degree of commonality. Industry organizations such as the National Rural Electric Cooperative Association (NRECA), the Electric Power Research Institute (EPRI), the American Public Power Association (APPA), and the Institute of Electrical and Electronics Engineers (IEEE) have made tremendous strides in preparing self-assessment templates, optimization guides, diagnostic techniques, and better definitions of reliability and power quality measures. In addition, public utility commissions have developed codes and methods for assessing performance that consider local needs. There is considerable overlap among these various organizations, and we see real opportunity and value in sharing these methods, guides, and standards in this report. This report provides a ''toolkit'' containing synopses of noteworthy reliability measurement practices. The toolkit has been developed to address the interests of three groups: electric power users, utilities, and regulators. The report will also serve to support activities to develop and share information among industry and regulatory participants about critical resources and practices. The toolkit has been developed by investigating the status of indices and definitions, surveying utility organizations on information sharing, and preparing summaries of reliability standards and monitoring requirements--the issues, needs, work under way, existing standards, practices and guidelines--for the following three classifications: (1) terms and definitions of reliability; (2) power quality standards, guidelines, and measurements; and (3) activities and organizations developing and sharing information on distribution reliability. As these synopses of reliability measurement practices are provided, it must be noted that an economic penalty may be associated with requiring too high a reliability level from the distribution system for all customers. It may be appropriate for the distribution system to supply only some base, generally accepted level of reliability. This base level would be adequate for the majority of customers. Users who need a higher level may find it economical to supply using distributed energy resources (DER) and other local solutions to reliability and power quality needs. Local solutions implemented by the customer may be the most cost-effective method for addressing the more stringent needs of a digital economy. These local solutions include energy storage, small distributed generators, and microgrids. This report also considers the market's role in addressing reliability issues and requirements. The customer's needs are discussed in view of issues such as power quality requirements of digital electronic equipment, the cost of outages, the cost of storage and new infrastructure, and natural gas prices. The market role in addressing these issues and requirements is explored. The economic considerations associated with the reliability issues are discussed, as well as the levels at which these economic decisions could be made. Finally, a discussion is provided of the role DER could play in addressing reliability needs, and the possible role of the market in providing needed levels of reliability.

  5. Methyl-parathion decreases sperm function and fertilization capacity after targeting spermatocytes and maturing spermatozoa

    SciTech Connect (OSTI)

    Pina-Guzman, Belem; Sanchez-Gutierrez, M.; Marchetti, Francesco; Hernandez-Ochoa, I.; Solis-Heredia, M.J .; Quintanilla-Vega, B.

    2009-05-03

    Paternal germline exposure to organophosphorous pesticides (OP) has been associated with reproductive failures and adverse effects in the offspring. Methyl parathion (Me-Pa), a worldwide-used OP, has reproductive adverse effects and is genotoxic to sperm. Oxidative damage has been involved in the genotoxic and reproductive effects of OP. The purpose of this study was to determine the effects of Me-Pa on spermatozoa function and ability to fertilize. Male mice were exposed to Me-Pa (20 mg/kg bw, i.p.) and spermatozoa from epididymis-vas deferens were collected at 7 or 28 days post-treatment (dpt) to assess the effects on maturing spermatozoa and spermatocytes, respectively. DNA damage was evaluated by nick translation (NT-positive cells) and SCSA (percentDFI); lipoperoxidation (LPO) by malondialdehyde production; sperm function by spontaneous- and induced-acrosome reactions (AR); mitochondrial membrane potential (MMP) by using the JC-1 flurochrome; and, fertilization ability by an in vitro assay and in vivo mating. Results showed alterations in DNA integrity (percentDFI and NT-positive cells) at 7 and 28 dpt, in addition to decreased sperm quality and a decrease in induced-AR; reduced MMP and LPO was observed only at 7 dpt. We found negative correlations between LPO and all sperm alterations. Altered sperm functional parameters were associated with reduced fertilization rates at both times, evaluated either in vitro or in vivo. These results show that Me-Pa exposure of maturing spermatozoa and spermatocytes affects many sperm functional parameters that result in a decreased fertilizing capacity. Oxidative stress seems to be a likely mechanism ofthe detrimental effects of Me-Pa in male germ cells.

  6. Final Technical Report Microwave Assisted Electrolyte Cell for Primary Aluminum Production

    SciTech Connect (OSTI)

    Xiaodi Huang; J.Y. Hwang

    2007-04-18

    This research addresses the high priority research need for developing inert anode and wetted cathode technology, as defined in the Aluminum Industry Technology Roadmap and Inert Anode Roadmap, with the performance targets: a) significantly reducing the energy intensity of aluminum production, b) ultimately eliminating anode-related CO2 emissions, and c) reducing aluminum production costs. This research intended to develop a new electrometallurgical extraction technology by introducing microwave irradiation into the current electrolytic cells for primary aluminum production. This technology aimed at accelerating the alumina electrolysis reduction rate and lowering the aluminum production temperature, coupled with the uses of nickel based superalloy inert anode, nickel based superalloy wetted cathode, and modified salt electrolyte. Michigan Technological University, collaborating with Cober Electronic and Century Aluminum, conducted bench-scale research for evaluation of this technology. This research included three sub-topics: a) fluoride microwave absorption; b) microwave assisted electrolytic cell design and fabrication; and c) aluminum electrowinning tests using the microwave assisted electrolytic cell. This research concludes that the typically used fluoride compound for aluminum electrowinning is not a good microwave absorbing material at room temperature. However, it becomes an excellent microwave absorbing material above 550°C. The electrowinning tests did not show benefit to introduce microwave irradiation into the electrolytic cell. The experiments revealed that the nickel-based superalloy is not suitable for use as a cathode material; although it wets with molten aluminum, it causes severe reaction with molten aluminum. In the anode experiments, the chosen superalloy did not meet corrosion resistance requirements. A nicked based alloy without iron content could be further investigated.

  7. Expression of hPNAS-4 Radiosensitizes Lewis Lung Cancer

    SciTech Connect (OSTI)

    Zeng Hui; Yuan Zhu; Zhu Hong; Li Lei; Shi Huashan; Wang Zi; Fan Yu; Deng Qian; Zeng Jianshuang; He Yinbo; Xiao Jianghong; Li Zhiping

    2012-11-15

    Purpose: This study aimed to transfer the hPNAS-4 gene, a novel apoptosis-related human gene, into Lewis lung cancer (LL2) and observe its radiosensitive effect on radiation therapy in vitro and in vivo. Methods and Materials: The hPNAS-4 gene was transfected into LL2 cells, and its expression was detected via western blot. Colony formation assay and flow cytometry were used to detect the growth and apoptosis of cells treated with irradiation/PNAS-4 in vitro. The hPNAS-4 gene was transferred into LL2-bearing mice through tail vein injection of the liposome/gene complex. The tumor volumes were recorded after radiation therapy. Proliferating cell nuclear antigen (PCNA) immunohistochemistry staining and terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) assay were performed to detect the tumor cell growth and apoptosis in vivo. Results: The hPNAS-4 gene was successfully transferred into LL2 cells and tumor tissue, and its overexpressions were confirmed via western blot analysis. Compared with the control, empty plasmid, hPNAS-4, radiation, and empty plasmid plus radiation groups, the hPNAS-4 plus radiation group more significantly inhibited growth and enhanced apoptosis of LL2 cells in vitro and in vivo (P<.05). Conclusions: The hPNAS-4 gene was successfully transferred into LL2 cells and tumor tissue and was expressed in both LL2 cell and tumor tissue. The hPNAS-4 gene therapy significantly enhanced growth inhibition and apoptosis of LL2 tumor cells by radiation therapy in vitro and in vivo. Therefore, it may be a potential radiosensitive treatment of radiation therapy for lung cancer.

  8. p53 Mutation suppresses adult neurogenesis in medaka fish (Oryzias latipes)

    SciTech Connect (OSTI)

    Isoe, Yasuko; Okuyama, Teruhiro; Taniguchi, Yoshihito; Kubo, Takeo; Takeuchi, Hideaki

    2012-07-13

    Highlights: Black-Right-Pointing-Pointer Progenitor migration is accompanied by an increase in their numbers in the adult brain. Black-Right-Pointing-Pointer p53 Mutation suppressed an increase in the number of the migrated progenitors. Black-Right-Pointing-Pointer The decreased progenitor number is not due to enhanced cell death. Black-Right-Pointing-Pointer p53 Mutation did not affect proliferation of stem cells. -- Abstract: Tumor suppressor p53 negatively regulates self-renewal of neural stem cells in the adult murine brain. Here, we report that the p53 null mutation in medaka fish (Oryzias latipes) suppressed neurogenesis in the telencephalon, independent of cell death. By using 5-bromo-29-deoxyuridine (BrdU) immunohistochemistry, we identified 18 proliferation zones in the brains of young medaka fish; in situ hybridization showed that p53 was expressed selectively in at least 12 proliferation zones. We also compared the number of BrdU-positive cells present in the whole telencephalon of wild-type (WT) and p53 mutant fish. Immediately after BrdU exposure, the number of BrdU-positive cells did not differ significantly between them. One week after BrdU-exposure, the BrdU-positive cells migrated from the proliferation zone, which was accompanied by an increased number in the WT brain. In contrast, no significant increase was observed in the p53 mutant brain. Terminal deoxynucleotidyl transferase (dUTP) nick end-labeling revealed that there was no significant difference in the number of apoptotic cells in the telencephalon of p53 mutant and WT medaka, suggesting that the decreased number of BrdU-positive cells in the mutant may be due to the suppression of proliferation rather than the enhancement of neural cell death. These results suggest that p53 positively regulates neurogenesis via cell proliferation.

  9. Secure IRC Server

    Energy Science and Technology Software Center (OSTI)

    2003-08-25

    The IRCD is an IRC server that was originally distributed by the IRCD Hybrid developer team for use as a server in IRC message over the public Internet. By supporting the IRC protocol defined in the IRC RFC, IRCD allows the users to create and join channels for group or one-to-one text-based instant messaging. It stores information about channels (e.g., whether it is public, secret, or invite-only, the topic set, membership) and users (who ismore » online and what channels they are members of). It receives messages for a specific user or channel and forwards these messages to the targeted destination. Since server-to-server communication is also supported, these targeted destinations may be connected to different IRC servers. Messages are exchanged over TCP connections that remain open between the client and the server. The IRCD is being used within the Pervasive Computing Collaboration Environment (PCCE) as the 'chat server' for message exchange over public and private channels. After an LBNLSecureMessaging(PCCE chat) client has been authenticated, the client connects to IRCD with its assigned nickname or 'nick.' The client can then create or join channels for group discussions or one-to-one conversations. These channels can have an initial mode of public or invite-only and the mode may be changed after creation. If a channel is public, any one online can join the discussion; if a channel is invite-only, users can only join if existing members of the channel explicity invite them. Users can be invited to any type of channel and users may be members of multiple channels simultaneously. For use with the PCCE environment, the IRCD application (which was written in C) was ported to Linux and has been tested and installed under Linux Redhat 7.2. The source code was also modified with SSL so that all messages exchanged over the network are encrypted. This modified IRC server also verifies with an authentication server that the client is who he or she claims to be and that this user is authorized to ain access to the IRCD.« less

  10. Student Travel to Pan-Am Congress of Plants & Biofuels in Merida, Mexico

    SciTech Connect (OSTI)

    Kimberly, Kimnach

    2014-04-01

    Department of Energy – Final Technical Report Grant Title: Student Travel to Pan-Am Congress of Plants & Biofuels in Merida, Mexico Award #: DE-FG02-08ER64612 Award Amount: $15,000.00 Award period: 6/15/2008 to 6/14/2009 ______________________________________________________________________________ The Pan American Congress on Plants and BioEnergy convened in Mérida, Mexico, June 22 to 25, 2008. The program was organized by Steve Long (University of Illinois) and Nick Carpita (Purdue University), along with co-organizers Marcos Buckeridge (University of São Paulo, Brazil) and Federico Sánchez (Universidad Nacional Autónoma de México). More than 200 scientists from over a dozen nations around the world gathered to discuss key issues surrounding the development of biofuel feedstocks and to report on their research in this area. This three day conference had invited speakers surrounding developing renewable and sustainable energy resources which are typically propelled by three important drivers – security, cost and environmental impact. The first day of the conference was delegated to governmental policy makers and designers of national research and plant biologists, agronomists, microbiologists, economists and ecologists in relation to bioenergy security in the Western Hemisphere that is sustainable and ecologically and economically sound. Speakers from countries that have already made themselves energy independent shared solutions to improve efficiency that is being researched. Venture capitalist and industry leaders also spoke on their commitment to economic success in a new green agroindustry. Days two and three explored bioenergy crops and introduced the participants to the breadth of the agricultural landscape, the underlying biology of bioenergy plants and new ideas to enhance biomass yield and quality of the energy crops of the future. These presentations educated the participants in an effort to develop energy strategies in countries across the world that become energy independent while developing economic growth and clean, reliable and affordable energy. Presenters educated student on reducing net greenhouse gas emissions, improving fuel efficiencies, indigenous energy alternative such as ethanol and improving bioenergy crop plants. Sessions surrounding developing bioenergy crop plants were held relating to the growth and development, cell wall synthesis and architecture to improve the next generation of energy plants. This grant was used to supplement registration and provide lodging support for graduate students, post-doctorals, and early career scientists attending the congress. Among these awardees partially funded by DOE and other agencies were 18 individuals, including nine graduate students, two post-doctorals, and seven early career scientists. The PIs on the grant worked closely with the Minority Affairs and International committees of ASPB to identify appropriate travel awardees; among the 18 awardees, nine were female, and two were African-American. Submitted & Certified by: Kimberly Kimnach