National Library of Energy BETA

Sample records for nf metropolitan statistical

  1. The Future Metropolitan Landscape

    E-Print Network [OSTI]

    Bosselmann, Peter; Ruggeri, Deni

    2007-01-01

    The Future Metropolitan Landscape Peter Bosselmann and DeniMetropolitan Landscape The Future Metropolitan Landscape Thecomplex phenomenon of “The Future Metropolitan Landscape. ”

  2. Office rent and labor availability in the Chicago Metropolitan Area

    E-Print Network [OSTI]

    Tang, Wencan, M.C.P. Massachusetts Institute of Technology

    2008-01-01

    This paper provides an empirical analysis of office rents using data from the 2000 U.S. Census and TWR office building data in the Chicago Metropolitan Statistical Area. The results indicate that rent levels respond to ...

  3. The Metropolitan Water District of Southern California

    Broader source: Energy.gov (indexed) [DOE]

    ERcomments@hq.doe.gov Comments on the Department of Energy's Quadrennial Energy Review: Water-Energy Nexus The Metropolitan Water District of Southern California (Metropolitan) is...

  4. Employee and Student Trip Reduction: First Year Results from Metropolitan Phoenix

    E-Print Network [OSTI]

    Burns, Elizabeth K.

    1994-01-01

    Results from Metropolitan Phoenix Elizabeth K. Bums Workingfrom Metropolitan Phoenix ElizabethK. Burns Department ofCounty Regional metropolitan Phoenix~ Arizona. compared with

  5. Metropolitan Accessibility and Transportation Sustainability:Sustainability

    E-Print Network [OSTI]

    Papalambros, Panos

    Metropolitan Accessibility and Transportation Sustainability:Sustainability: Comparative Reduce (fulfillment of)Promote Sustainability: Meet needs of (fulfillment of) needs present Institute SMART Sustainable Mobility and Accessibility Research andSMART Sustainable Mobility

  6. TNAP, a Novel Repressor of NF-B-inducing Kinase, Suppresses NF-B Activation*

    E-Print Network [OSTI]

    Hu, Wen-Hui

    responses, oncogenesis, apoptosis, and neuronal signaling (1­5). To date two principal pathways for NF- B

  7. U.S. Metropolitan Spatial Structure and Employment Growth 

    E-Print Network [OSTI]

    Huang, Xiaoyan

    2014-08-13

    This study explores the influence of US metropolitan spatial structure evolution on regional employment growth rate. The first part of this study investigates the evolution of US metropolitan spatial structures from 2000 to 2010. At the macro level...

  8. Correction to NF 3 , the greenhouse gas missing from Kyoto

    E-Print Network [OSTI]

    Prather, Michael J; Hsu, Juno

    2010-01-01

    J. Hsu (2008), NF 3 , the greenhouse gas missing from Kyoto,Correction to “NF 3 , the greenhouse gas missing from Kyoto”2010), Correction to “NF 3 , the greenhouse gas missing from

  9. Estimating overdispersion in the assessment of crime reduction interventions Paul R. Marchant, Leeds Metropolitan University, School of Information m

    E-Print Network [OSTI]

    Barber, Stuart

    , Leeds Metropolitan University, School of Information m Management, Leeds, LS6 3QS; email: p.marchant@leedsmet.ac.uk; phone: 0113 283 6109; fax: 0113 283 7599 Paul D. Baxter* and Stuart Barber, University of Leeds, Department of Statistics, Leeds LS2 9JT; email: pdbaxt@maths.leeds.ac.uk, stuart@maths.leeds.ac.uk; phone

  10. Columbia metropolitan Convention Center Columbia, South Carolina

    E-Print Network [OSTI]

    Valtorta, Marco

    at the Columbia metropolitan Convention Center Columbia, South Carolina marCh 23-25, 2011 Bringing Center 101 linColn Street Bringing Open SOurce tO the SOutheaSt Columbia, South Carolina developerS, edu team member, Rails Bringing Open SOurce tO the SOutheaSt Columbia, South Carolina POSSCON 2010 kicked

  11. Metropolitan Community College (Missouri-all locations)

    E-Print Network [OSTI]

    OF KANSAS Department of Design Photo Media-B.F.A Number to call at KU for advising: (785) 864-3500 Website/Senior level for graduation. Photo Media Requirements: KU Course Requirements Metropolitan Course Equivalents Critical Reading and Writing 3 ENGL 102 Composition and Reading II 3 GE21 GE11 Core: Core ENGL 209 Intro

  12. TransBorder 2035 Metropolitan Transportation Plan 

    E-Print Network [OSTI]

    El Paso Metropolitan Planning Organization

    2007-11-16

    Investigacion y Planeacion (IMIP), Tigua Tribal Government, New Mexico Environmental Department, Texas Commission on Environmental Quality, City of El Paso, and surrounding towns. The MPO staff is tasked with establishing an impartial setting for effective... Metropolitan Planning Organization www.elpasompo.org 3.3 Environmental Justice Environmental Justice (EJ) is a concept that has a major impact in the transportation planning process. The goal of EJ, as it relates to transportation...

  13. Chicago Metropolitan Agency for Planning Data Dashboard | Department...

    Energy Savers [EERE]

    Metropolitan Agency for Planning Data Dashboard More Documents & Publications Austin Energy Data Dashboard Massachusetts -- SEP Data Dashboard Phoenix, Arizona Data Dashboard...

  14. Involuntary Mobility, Gender, and Travel Demand Management in Metropolitan Phoenix

    E-Print Network [OSTI]

    Burns, Elizabeth K.

    1995-01-01

    1988. “Transportation in the Phoenix Metropolitan Area. ” In218. Luckingham, Bradford. 1989. Phoenix: The History of aYear Ending December 31, 1995. Phoenix: Maricopa County Trip

  15. Alexandria/Pineville Metropolitan Transportation Plan MTP 2029 

    E-Print Network [OSTI]

    Rapides Area Planning Commission

    2005-01-01

    stream_source_info Alexandria_Pineville Metropolitan Transportation Plan MTP 2029.pdf.txt stream_content_type text/plain stream_size 90 Content-Encoding ISO-8859-1 stream_name Alexandria_Pineville Metropolitan Transportation Plan MTP...

  16. Metropolitan Road Traffic Simulation on FPGAs.

    SciTech Connect (OSTI)

    Tripp J. L. (Justin L.); Mortveit, H. S. (Henning S.); Hansson, A. A. (Anders A.); Gokhale, M. (Maya)

    2005-01-01

    This work demonstrates that road traffic simulation of entire metropolitan areas is possible with reconfigurable supercomputing that combines 64-bit microprocessors and FPGAs in a high bandwidth, low latency interconnect. Previously, traffic simulation on FPGAs was limited to very short road segments or required a very large number of FPGAs. Our data streaming approach overcomes scaling issues associated with direct implementations and still allows for high-level parallelism by dividing the data sets between hardware and software across the reconfigurable supercomputer. Using one FPGA on the Cray XD1 supercomputer, we are able to achieve a 34.4 x speed up over the AMD microprocessor. System integration issues must be optimized to exploit this speedup in the overall simulation.

  17. Transit Access and Regional Coordination in Metropolitan Detroit

    E-Print Network [OSTI]

    LaRose, Jeremiah; Netto, Alyssa; Thomas, Trevor

    2014-01-01

    groups on both sides of Detroit’s borders, and a great dealbadly needed transit service in Detroit. Planetizen, May 22.Coordination in Metropolitan Detroit Jeremiah LaRose, MURP '

  18. Efficient detection of contagious outbreaks in massive metropolitan encounter networks

    E-Print Network [OSTI]

    Sun, Lijun

    Physical contact remains difficult to trace in large metropolitan networks, though it is a key vehicle for the transmission of contagious outbreaks. Co-presence encounters during daily transit use provide us with a city-scale ...

  19. Hot Springs Metropolitan Planning Organization 2030 Long Range Transportation Plan 

    E-Print Network [OSTI]

    Hot Springs Metropolitan Planning Organization

    2005-11-03

    of Mountain Pine Hot Springs Village The Greater Hot Springs Chamber of Commerce The Arkansas State Highway and Transportation Department In Cooperation With United States Department of Transportation Federal Highway Administration Federal Transit... Administration 2030 Long Range Transportation Plan for the Hot Springs Area Metropolitan Planning Organization This LRTP has been funded with federal Metropolitan Planning (PL) funds through the Federal Highway Administration, Section 5303 funds...

  20. NF kappa B expression and matrix metalloproteinase activity in hypertension

    E-Print Network [OSTI]

    Wu, Kwan-I

    2009-01-01

    without PDTC treatment by gelatin gel zymography. Chapter 2Labeling of NF-?B………………………………14 Gelatin Gel ZymographyPDTC treatment measured by gelatin zymography…………………34

  1. Erratum: NF3, the greenhouse gas missing from Kyoto (Geophysical Research Letters (2010) 37 (L11807))

    E-Print Network [OSTI]

    Prather, MJ; Hsu, J

    2010-01-01

    J. Hsu (2008), NF 3 , the greenhouse gas missing from Kyoto,Correction to “NF 3 , the greenhouse gas missing from Kyoto”2010), Correction to “NF 3 , the greenhouse gas missing from

  2. Department of Statistics STATISTICS COLLOQUIUM

    E-Print Network [OSTI]

    Department of Statistics STATISTICS COLLOQUIUM MATTHEW STEPHENS Departments of Statistics and Human statistical methods in genomics, among other areas of application. A typical workflow consists of i

  3. Department of Statistics STATISTICS COLLOQUIUM

    E-Print Network [OSTI]

    Department of Statistics STATISTICS COLLOQUIUM KAMIAR RAD Department of Statistics Columbia carrying a finite total amount of information, the asymptotic sufficient statistics of the stimulus

  4. Department of Statistics STATISTICS COLLOQUIUM

    E-Print Network [OSTI]

    Department of Statistics STATISTICS COLLOQUIUM HUIBIN ZHOU Department of Statistics Yale University to obtain statistical inference for estimation of Gaussian Graphical Model? A regression approach

  5. Department of Statistics STATISTICS COLLOQUIUM

    E-Print Network [OSTI]

    Department of Statistics STATISTICS COLLOQUIUM GOURAB MUKHERJEE Department of Statistics Stanford directions in statistical probability forecasting. Building on these parallels we present a frequentist

  6. Department of Statistics STATISTICS COLLOQUIUM

    E-Print Network [OSTI]

    Department of Statistics STATISTICS COLLOQUIUM INGRAM OLKIN Department of Statistics Stanford probability, statistics, combinatorics and graphs, numerical analysis and matrix theory. Special emphasis

  7. Department of Statistics STATISTICS COLLOQUIUM

    E-Print Network [OSTI]

    Department of Statistics STATISTICS COLLOQUIUM ZONGMING MA Department of Statistics University (CCA) is a widely used multivariate statistical technique for exploring the relation between two sets

  8. Sustainable metropolitan growth strategies : exploring the role of the built environment

    E-Print Network [OSTI]

    Diao, Mi, Ph. D. Massachusetts Institute of Technology

    2010-01-01

    The sustainability of metropolitan areas has been considered one of the most significant social challenges worldwide. Among the various policy options to achieve sustainable metropolitan growth, smart-growth strategies ...

  9. Governing the metropolis : the evolution of cooperative metropolitan governance in Mexico City's public transportation

    E-Print Network [OSTI]

    Cenizal, Callida

    2015-01-01

    What enables cooperation at the metropolitan scale? This thesis explores public transportation planning in the Mexico City metropolitan area (MCMA) for empirical evidence to better understand what institutional, financial, ...

  10. DeKalb County/Metropolitan Atlanta Alternative Fuel and Advanced...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    60tifrancis2012o.pdf More Documents & Publications DeKalb CountyMetropolitan Atlanta Alternative Fuel and Advanced Technology Vehicle Project DeKalb CountyMetropolitan...

  11. DeKalb County/Metropolitan Atlanta Alternative Fuel and Advanced...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    vt060francis2010p.pdf More Documents & Publications DeKalb CountyMetropolitan Atlanta Alternative Fuel and Advanced Technology Vehicle Project DeKalb CountyMetropolitan...

  12. DeKalb County/Metropolitan Atlanta Alternative Fuel and Advanced...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    60tifrancis2011p.pdf More Documents & Publications DeKalb CountyMetropolitan Atlanta Alternative Fuel and Advanced Technology Vehicle Project DeKalb CountyMetropolitan...

  13. Cloning and expression of equine NF-kB2 

    E-Print Network [OSTI]

    Mirhosseini, Negin

    2009-05-15

    ........................ 51 xi LIST OF TABLES Page Table 1 Primers to generate full length NF-?B2... of the interaction between EIAV S2 and equine NF-?B in the yeast two hybrid system........................... 43 Table 7 Primers and probes for quantitative PCR.......................................... 48 1 CHAPTER I INTRODUCTION 1 Equine Infectious...

  14. Baskerville, C. A.; and Merguerian, Charles, 1982, Tectonic history of the New York Metropolitan area.

    E-Print Network [OSTI]

    Merguerian, Charles

    Baskerville, C. A.; and Merguerian, Charles, 1982, Tectonic history of the New York Metropolitan area. Urban field mapping of basement (literally in some cases) rocks in the New York Metropolitan area: Baskerville, C. A.; and Merguerian, Charles, 1982, Tectonic history of the New York Metropolitan area (abs

  15. Fargo-Moorhead Metropolitan Flood Risk Management Feasibility Study

    E-Print Network [OSTI]

    US Army Corps of Engineers

    Fargo-Moorhead Metropolitan Flood Risk Management Feasibility Study North Dakota and Minnesota Quality Bulletin for Peer Review released December 16, 2004. This flood risk management feasibility study flood risk management and recreation needs of the study area in February 2010. An IEPR of the draft

  16. The structure of agriculture in metropolitan and nonmetropolitan America 

    E-Print Network [OSTI]

    Scott, Michelle L

    2003-01-01

    the following questions: (1) What was the structure of U.S. agricultural production systems in 1992 and had this structure changed by 1997? (2) What was the relationship between metropolitan proximity and U.S. agristructure and its changes from 1992 to 1997...

  17. Pricing Schemes for Metropolitan Traffic Data Markets Negin Golrezaei1

    E-Print Network [OSTI]

    Shahabi, Cyrus

    Marshall School of Business, University of Southern California, Los Angeles, CA 90089 {golrezae, nazerzad of the pricing schemes applicable to data marketplaces in the context of transportation traffic data. Traffic congestion is a growing problem in many metropolitan areas. It not only wastes our time and energy

  18. Global Statistics

    E-Print Network [OSTI]

    Crow, Ben D

    2006-01-01

    of Globalization: Statistics Weiss, L. (1997). "of Globalization: Statistics Milanovic, B. (1999). Truethe focus of global statistics, particularly in relation to

  19. Statistical Sciences

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    LeeAnn Martinez (505) 667-3308 Email Find Expertise header Search our employee skills database Statistical Sciences Statistical Sciences provides statistical reasoning and...

  20. Effects of water chemistry on NF/RO membrane structure and performance

    E-Print Network [OSTI]

    Mo, Yibing

    2013-01-01

    potable water and seawater desalination. NF/RO are effectivemembranes under seawater conditions, Desalination, 247 (

  1. Department of Statistics STATISTICS COLLOQUIUM

    E-Print Network [OSTI]

    Department of Statistics STATISTICS COLLOQUIUM Joint seminar with Stevanovich Center PHILIPPE RIGOLLET Operations Research and Financial Engineering, Princeton University The Statistical Price to Pay ABSTRACT Computational limitations of statistical problems have largely been ignored or simply over- come

  2. NF 3 , the greenhouse gas missing from Kyoto

    E-Print Network [OSTI]

    Prather, Michael J; Hsu, Juno

    2008-01-01

    of high-GWP, long-lived, greenhouse gases like NF 3 shouldbe included in the national greenhouse gas inventories onceto expand the list of greenhouse gases for the second

  3. NF-?B Fans the Flames of Lung Carcinogenesis

    E-Print Network [OSTI]

    Jacks, Tyler E.

    This perspective on Deng et al. (beginning on p. 424 in this issue of the journal) examines the link between NF-?B and lung tumorigenesis. Experiments in genetically engineered mouse models of lung cancers are elucidating ...

  4. 32. Statistics 1 32. STATISTICS

    E-Print Network [OSTI]

    Masci, Frank

    an overview of statistical methods used in High Energy Physics. In statistics, we are interested in using and their statistical uncertainties in High Energy Physics. In Bayesian statistics, the interpretation of probability32. Statistics 1 32. STATISTICS Revised September 2007 by G. Cowan (RHUL). This chapter gives

  5. Department of Statistics STATISTICS COLLOQUIUM

    E-Print Network [OSTI]

    Department of Statistics STATISTICS COLLOQUIUM ERIC KOLACZYK Department of Statistics Boston University Statistical Analysis of Network Data: (Re)visiting the Foundations MONDAY, October 13, 2014, at 4, statistical methods and modeling have been central to these efforts. But how well do we truly understand

  6. Department of Statistics STATISTICS COLLOQUIUM

    E-Print Network [OSTI]

    Department of Statistics STATISTICS COLLOQUIUM PO-LING LOH Department of Statistics University the seminar in Eckhart 110 ABSTRACT Noisy and missing data are prevalent in many real-world statistical, and provide theoretical guarantees for the statistical consistency of our methods. Although our estimators

  7. Department of Statistics STATISTICS COLLOQUIUM

    E-Print Network [OSTI]

    Department of Statistics STATISTICS COLLOQUIUM ERNST WIT Statistics and Probability University devices collect a lot of information, typically about few independent statistical subjects or units statistics. In certain special cases the method can be tweaked to obtain L1-penalized GLM solution paths

  8. Department of Statistics STATISTICS COLLOQUIUM

    E-Print Network [OSTI]

    Department of Statistics STATISTICS COLLOQUIUM NOUREDDINE EL KAROUI Department of Statistics will discuss the behavior of widely used statistical methods in the high-dimensional setting where the number surprising statistical phenomena occur: for instance, maximum likelihood methods are shown to be (grossly

  9. Department of Statistics STATISTICS COLLOQUIUM

    E-Print Network [OSTI]

    Department of Statistics STATISTICS COLLOQUIUM GONGJUN XU Department of Statistics Columbia University Statistical Inference for Diagnostic Classification Models MONDAY, February 18, 2013 at 4:00 PM-driven construction (estimation) of the Q-matrix and related statistical issues of DCMs. I will first give

  10. Car Based Transport and Transit Oriented Metropolitan —— Chinese Urban Motorization Pathways

    E-Print Network [OSTI]

    Ximing, Lu

    2008-01-01

    Car Based Transport and Transit Oriented Metropolitan ——the automobile, the result is that car ownership has becomeof American families lack cars. In China, however, large

  11. Washington Metropolitan Area Transit Authority: Compressed Natural Gas Transit Bus Evaluation

    SciTech Connect (OSTI)

    Chandler, K.; Eberts, E.; Melendez, M.

    2006-04-01

    Evaluates compressed natural gas (CNG) powered transit buses at Washington Metropolitan Area Transit Authority (WMATA), providing a comparison between them and standard diesel transit buses.

  12. The Origins of Metropolitan Transportation Planning in Travel Demand Forecasting, 1944-1962

    E-Print Network [OSTI]

    Deutsch, Cheryl

    2013-01-01

    predictions for the Detroit area. In Highway Research Board4: Desire line charts from Detroit, 1942………………………………………………….transportation research in the Detroit Metropolitan Area

  13. A gradient analysis of urban landscape pattern: a case study from the Phoenix metropolitan region, Arizona, USA

    E-Print Network [OSTI]

    Wu, Jianguo "Jingle"

    A gradient analysis of urban landscape pattern: a case study from the Phoenix metropolitan region the spatial pattern of urbanization in the Phoenix metropolitan area, Arizona, USA. Several landscape metrics

  14. Department of Statistics STATISTICS COLLOQUIUM

    E-Print Network [OSTI]

    Department of Statistics STATISTICS COLLOQUIUM ROBERT NOWAK Department of Electrical and Computer-dimensional statistical models to capture the complexity of such problems. Most of the work in this direction has focused of statistical inference. These procedures automatically adapt the measurements in order to focus and optimize

  15. Department of Statistics STATISTICS COLLOQUIUM

    E-Print Network [OSTI]

    Department of Statistics STATISTICS COLLOQUIUM SRIRAM SANKARARAMAN Department of Genetics Harvard Medical School Statistical Models for Analyzing Ancient Human Admixture WEDNESDAY, January 21, 2015, at 4 become available, as well as appropriate statistical models. In the first part of my talk, I will focus

  16. Department of Statistics STATISTICS COLLOQUIUM

    E-Print Network [OSTI]

    Department of Statistics STATISTICS COLLOQUIUM PIOTR ZWIERNIK Department of Mathematics University of Genoa Understanding Statistical Models Through Their Geometry MONDAY, January 26, 2015, at 4:00 PM and Gaussian statistical models have a rich geometric structure and can be often viewed as algebraic sets

  17. Haploid reporter screens aimed at identification of NF-kappaB regulators

    E-Print Network [OSTI]

    Lee, Clarissa Ci

    2014-01-01

    Nuclear factor-kappaB (NF-KB) is a family of transcription factors that are essential for execution of both the innate and the adaptive immune response. NF-KB regulates hundreds of genes involved in critical processes such ...

  18. Topographically-Based Real-Time Traffic Anomaly Detection in a Metropolitan Highway System

    E-Print Network [OSTI]

    Grossman, Robert

    Topographically-Based Real-Time Traffic Anomaly Detection in a Metropolitan Highway System Rajmonda metropolitan area. Our Chicago Alert System (CAS) considers both the spatial and temporal aspects of the data of attack, the need for real-time traffic management is crucial. Real-time traffic management encompasses

  19. Photochemical age determinations in the Phoenix metropolitan area L. I. Kleinman,1

    E-Print Network [OSTI]

    Photochemical age determinations in the Phoenix metropolitan area L. I. Kleinman,1 P. H. Daum,1 Y oxidant field campaign conducted in the Phoenix air basin in the late spring of 1998. Sampling was done, Phoenix Citation: Kleinman, L. I., et al., Photochemical age determinations in the Phoenix metropolitan

  20. Debris flows from small catchments of the Ma Ha Tuak Range, metropolitan Phoenix, Arizona

    E-Print Network [OSTI]

    Dorn, Ron

    Debris flows from small catchments of the Ma Ha Tuak Range, metropolitan Phoenix, Arizona Ronald I from tiny but steep mountain catchments throughout metropolitan Phoenix, Arizona, USA. Urban growth downtown Phoenix, was selected to determine the feasibility of using the varnish microlaminations (VML

  1. Hadron-Hadron Interactions from $N_f=2+1+1$ Lattice QCD: isospin-2 $??$ scattering length

    E-Print Network [OSTI]

    C. Helmes; C. Jost; B. Knippschild; C. Liu; J. Liu; L. Liu; C. Urbach; M. Ueding; Z. Wang; M. Werner

    2015-06-01

    We present results for the $I=2$ $\\pi\\pi$ scattering length using $N_f=2+1+1$ twisted mass lattice QCD for three values of the lattice spacing and a range of pion mass values. Due to the use of Laplacian Heaviside smearing our statistical errors are reduced compared to previous lattice studies. A detailed investigation of systematic effects such as discretisation effects, volume effects, and pollution of excited and thermal states is performed. After extrapolation to the physical point using chiral perturbation theory at NLO we obtain $M_\\pi a_0=-0.0442(2)_\\mathrm{stat}(^{+4}_{-0})_\\mathrm{sys}$.

  2. Term statistics Zipf's law text statistics

    E-Print Network [OSTI]

    Lu, Jianguo

    Term statistics Zipf's law text statistics October 20, 2014 text statistics 1 / 19 #12;Term statistics Zipf's law Overview 1 Term statistics 2 Zipf's law text statistics 2 / 19 #12;Term statistics Zipf's law Outline 1 Term statistics 2 Zipf's law text statistics 3 / 19 #12;Term statistics Zipf's law Model

  3. (Draft) Community air pollution and mortality: Analysis of 1980 data from US metropolitan areas

    SciTech Connect (OSTI)

    Lipfert, F.W.

    1992-11-01

    1980 data from up to 149 metropolitan areas were used to define cross-sectional associations between community air pollution and ``excess`` human mortality. The regression model proposed by Ozkaynak and Thurston (1987), which accounted for age, race, education, poverty, and population density, was evaluated and several new models were developed. The new models also accounted for migration, drinking water hardness, and smoking, and included a more detailed description of race. Cause-of-death categories analyzed include all causes, all ``non-external`` causes, major cardiovascular diseases, and chronic obstructive pulmonary diseases (COPD). Both annual mortality rates and their logarithms were analyzed. Air quality data were obtained from the EPA AIRS database (TSP, SO{sub 4}{sup =}, Mn, and ozone) and from the inhalable particulate network (PM{sub 15}, PM{sub 2.5} and SO{sub 4}{sup =}, for 63{sup 4} locations). The data on particulates were averaged across all monitoring stations available for each SMSA and the TSP data were restricted to the year 1980. The associations between mortality and air pollution were found to be dependent on the socioeconomic factors included in the models, the specific locations included in the data set, and the type of statistical model used. Statistically significant associations were found as follows: between TSP and mortality due to non-external causes with log-linear models, but not with a linear model betweenestimated 10-year average (1980--90) ozone levels and 1980 non-external and cardiovascular deaths; and between TSP and COPD mortality for both linear and log-linear models. When the sulfate contribution to TSP was subtracted, the relationship with COPD mortality was strengthened.

  4. (Draft) Community air pollution and mortality: Analysis of 1980 data from US metropolitan areas

    SciTech Connect (OSTI)

    Lipfert, F.W.

    1992-11-01

    1980 data from up to 149 metropolitan areas were used to define cross-sectional associations between community air pollution and excess'' human mortality. The regression model proposed by Ozkaynak and Thurston (1987), which accounted for age, race, education, poverty, and population density, was evaluated and several new models were developed. The new models also accounted for migration, drinking water hardness, and smoking, and included a more detailed description of race. Cause-of-death categories analyzed include all causes, all non-external'' causes, major cardiovascular diseases, and chronic obstructive pulmonary diseases (COPD). Both annual mortality rates and their logarithms were analyzed. Air quality data were obtained from the EPA AIRS database (TSP, SO[sub 4][sup =], Mn, and ozone) and from the inhalable particulate network (PM[sub 15], PM[sub 2.5] and SO[sub 4][sup =], for 63[sup 4] locations). The data on particulates were averaged across all monitoring stations available for each SMSA and the TSP data were restricted to the year 1980. The associations between mortality and air pollution were found to be dependent on the socioeconomic factors included in the models, the specific locations included in the data set, and the type of statistical model used. Statistically significant associations were found as follows: between TSP and mortality due to non-external causes with log-linear models, but not with a linear model betweenestimated 10-year average (1980--90) ozone levels and 1980 non-external and cardiovascular deaths; and between TSP and COPD mortality for both linear and log-linear models. When the sulfate contribution to TSP was subtracted, the relationship with COPD mortality was strengthened.

  5. Multiplex networks in metropolitan areas: generic features and local effects

    E-Print Network [OSTI]

    Strano, Emanuele; Dobson, Simon; Barthelemy, Marc

    2015-01-01

    Most large cities are spanned by more than one transportation system. These different modes of transport have usually been studied separately: it is however important to understand the impact on urban systems of the coupling between them and we report in this paper an empirical analysis of the coupling between the street network and the subway for the two large metropolitan areas of London and New York. We observe a similar behaviour for network quantities related to quickest paths suggesting the existence of generic mechanisms operating beyond the local peculiarities of the specific cities studied. An analysis of the betweenness centrality distribution shows that the introduction of underground networks operate as a decentralising force creating congestions in places located at the end of underground lines. Also, we find that increasing the speed of subways is not always beneficial and may lead to unwanted uneven spatial distributions of accessibility. In fact, for London -- but not for New York -- there is ...

  6. Efficient detection of contagious outbreaks in massive metropolitan encounter networks

    E-Print Network [OSTI]

    Sun, Lijun; Lee, Der-Horng; Cebrian, Manuel

    2014-01-01

    Physical contact remains difficult to trace in large metropolitan networks, though it is a key vehicle for the transmission of contagious outbreaks. Co-presence encounters during daily transit use provide us with a city-scale time-resolved physical contact network, consisting of 1 billion contacts among 3 million transit users. Here, we study the advantage that knowledge of such co-presence structures may provide for early detection of contagious outbreaks. We first examine the "friend sensor" scheme --- a simple, but universal strategy requiring only local information --- and demonstrate that it provides significant early detection of simulated outbreaks. Taking advantage of the full network structure, we then identify advanced "global sensor sets", obtaining substantial early warning times savings over the friends sensor scheme. Individuals with highest number of encounters are the most efficient sensors, with performance comparable to individuals with the highest travel frequency, exploratory behavior and ...

  7. Unequal development : decentralization and fiscal disparities in the Metropolitan Zone of the Valley of Mexico

    E-Print Network [OSTI]

    Raich, Uri

    2006-01-01

    This study is about the impact of decentralization in metropolitan areas. Studies of fiscal decentralization have largely centered on the formal tiers of government, without looking at the effects of this process on the ...

  8. Impact of primary formaldehyde on air pollution in the Mexico City Metropolitan Area

    E-Print Network [OSTI]

    Lei, Wenfang

    Formaldehyde (HCHO) is a radical source that plays an important role in urban atmospheric chemistry and ozone formation. The Mexico City Metropolitan Area (MCMA) is characterized by high anthropogenic emissions of HCHO ...

  9. Metropolitan governance and local land use planning in Boston, Denver, and Portland

    E-Print Network [OSTI]

    Rosan, Christina

    2007-01-01

    Metropolitan areas across the U.S. are characterized by sprawling development which uses larger amounts of open space than necessary, leads to the inefficient use of energy and water, increases social inequality, and causes ...

  10. Rainbow statistics

    E-Print Network [OSTI]

    Michele Arzano; Dario Benedetti

    2008-09-04

    Non-commutative quantum field theories and their global quantum group symmetries provide an intriguing attempt to go beyond the realm of standard local quantum field theory. A common feature of these models is that the quantum group symmetry of their Hilbert spaces induces additional structure in the multiparticle states which reflects a non-trivial momentum-dependent statistics. We investigate the properties of this "rainbow statistics" in the particular context of $\\kappa$-quantum fields and discuss the analogies/differences with models with twisted statistics.

  11. Finite density phase transition of QCD with $N_f=4$ and $N_f=2$ using canonical ensemble method

    E-Print Network [OSTI]

    Anyi Li; Andrei Alexandru; Keh-Fei Liu; Xiangfei Meng

    2010-10-01

    In a progress toward searching for the QCD critical point, we study the finite density phase transition of $N_f = 4$ and 2 lattice QCD at finite temperature with the canonical ensemble approach. We develop a winding number expansion method to accurately project out the particle number from the fermion determinant which greatly extends the applicable range of baryon number sectors to make the study feasible. Our lattice simulation was carried out with the clover fermions and improved gauge action. For a given temperature, we calculate the baryon chemical potential from the canonical approach to look for the mixed phase as a signal for the first order phase transition. In the case of $N_f=4$, we observe an "S-shape" structure in the chemical potential-density plane due to the surface tension of the mixed phase in a finite volume which is a signal for the first order phase transition. We use the Maxwell construction to determine the phase boundaries for three temperatures below $T_c$. The intersecting point of the two extrapolated boundaries turns out to be at the expected first order transition point at $T_c$ with $\\mu = 0$. This serves as a check for our method of identifying the critical point. We also studied the $N_f =2$ case, but do not see a signal of the mixed phase for temperature as low as 0.83 $T_c$.

  12. Truck transport of RAM: Risk effects of avoiding metropolitan areas

    SciTech Connect (OSTI)

    Mills, G.S.; Neuhauser, K.S.

    1997-11-01

    In the transport of radioactive material (RAM), e.g., spent nuclear fuel (SNF), stakeholders are generally most concerned about risks in high population density areas along transportation routes because of the perceived high consequences of potential accidents. The most significant portions of a transcontinental route and an alternative examined previously were evaluated again using population density data derived from US Census Block data. This method of characterizing population that adjoins route segments offers improved resolution of population density variations, especially in high population density areas along typical transport routes. Calculated incident free doses and accident dose risks for these routes, and the rural, suburban and urban segments are presented for comparison of their relative magnitudes. The results indicate that modification of this route to avoid major metropolitan areas through use of non-Interstate highways increases total risk yet does not eliminate a relatively small urban component of the accident dose risk. This conclusion is not altered by improved resolution of route segments adjoining high density populations.

  13. Regional planning and operations architectures as means to foster transportation integration in the Mexico City Metropolitan Area

    E-Print Network [OSTI]

    Ortiz Mantilla, Bernardo Jose, 1977-

    2005-01-01

    The MCMA complexity in political, institutional, economical, and jurisdictional terms has resulted in limited coordination between MCMA authorities that in conjunction with the limited role of metropolitan transportation ...

  14. Introductory Statistics,

    E-Print Network [OSTI]

    Hunter, David

    , following the publication of Venables & Ripley (1994). [See p. 1. Where that takes a significantly better­Plus include dynamic graphics (x6.3, brush and spin) and the classical statistics functions (x9 environment. It will help to have the library ripley available --- it should be in the same source

  15. Statistics and the Sciences

    E-Print Network [OSTI]

    Jan de Leeuw

    2011-01-01

    with Real Data ? Annals Statistics, of 5:1055-1098, 1977.The Foundations of Statistics - Are There Any ? Synthese, [Statistics and the Sciences Jan de Leeuw UCLA Statistics

  16. Update on a short-distance D^0-meson mixing calculation with $N_f=2+1$ flavors

    E-Print Network [OSTI]

    C. C. Chang; C. Bernard; C. M. Bouchard; A. X. El-Khadra; E. D. Freeland; E. Gámiz; A. S. Kronfeld; J. Laiho; R. S. Van de Water

    2014-12-13

    We present an update on our calculation of the short-distance $D^0$-meson mixing hadronic matrix elements. The analysis is performed on the MILC collaboration's $N_f=2+1$ asqtad configurations. We use asqtad light valence quarks and the Sheikoleslami-Wohlert action with the Fermilab interpretation for the valence charm quark. SU(3), partially quenched, rooted, staggered heavy-meson chiral perturbation theory is used to extrapolate to the chiral-continuum limit. Systematic errors arising from the chiral-continuum extrapolation, heavy-quark discretization, and quark-mass uncertainties are folded into the statistical errors from the chiral-continuum fits with methods of Bayesian inference. A preliminary error budget for all five operators is presented.

  17. Hadron-Hadron Interactions from $N_f=2+1+1$ Lattice QCD: isospin-2 $\\pi\\pi$ scattering length

    E-Print Network [OSTI]

    Helmes, C; Knippschild, B; Liu, C; Liu, J; Liu, L; Urbach, C; Ueding, M; Wang, Z; Werner, M

    2015-01-01

    We present results for the $I=2$ $\\pi\\pi$ scattering length using $N_f=2+1+1$ twisted mass lattice QCD for three values of the lattice spacing and a range of pion mass values. Due to the use of Laplacian Heaviside smearing our statistical errors are reduced compared to previous lattice studies. A detailed investigation of systematic effects such as discretisation effects, volume effects, and pollution of excited and thermal states is performed. After extrapolation to the physical point using chiral perturbation theory at NLO we obtain $M_\\pi a_0=-0.0442(2)_\\mathrm{stat}(^{+4}_{-0})_\\mathrm{sys}$.

  18. Spike statistics

    E-Print Network [OSTI]

    J. Mark Heinzle; Claes Uggla

    2012-12-21

    In this paper we explore stochastical and statistical properties of so-called recurring spike induced Kasner sequences. Such sequences arise in recurring spike formation, which is needed together with the more familiar BKL scenario to yield a complete description of generic spacelike singularities. In particular we derive a probability distribution for recurring spike induced Kasner sequences, complementing similar available BKL results, which makes comparisons possible. As examples of applications, we derive results for so-called large and small curvature phases and the Hubble-normalized Weyl scalar.

  19. Usage Statistics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home RoomPreservationBio-Inspired SolarAbout /Two0 - 19PortalStatus UpdatesUsage Statistics Usage

  20. DraftApril 7, 2009 Features of Climate-Smart Metropolitan Economies

    E-Print Network [OSTI]

    emissions of carbon dioxide.) Residential and commercial buildings account for 39 percent of the carbon. To help provide benchmarks and expand our understanding of carbon emissions, this chapter quantifies highway transportation and residential carbon emissions of the 100 largest U.S. metropolitan areas in 2000

  1. DraftApril 7, 2009 Features of Climate-Smart Metropolitan Economies

    E-Print Network [OSTI]

    , such as coal and oil, for energy.3 (Here, the terms carbon emissions or carbon footprint both indicate of the economy, and (4) carbon intensity of the energy system.8 Shrinking the nation's carbon footprint, while solving environmental challenges. With supportive federal policies, metropolitan areas can provide the low-carbon

  2. Fuel-Based On-Road Motor Vehicle Emissions Inventory for the Denver Metropolitan Area

    E-Print Network [OSTI]

    Denver, University of

    Fuel-Based On-Road Motor Vehicle Emissions Inventory for the Denver Metropolitan Area Sajal S of obtaining on-road emissions inventories has been developed. This technique calculates emission factors these factors with fuel use data, available from tax records, yields a fuel based emission inventory. We have

  3. FARGO-MOORHEAD METROPOLITAN AREA, ND AND MN FLOOD RISK MANAGEMENT PROJECT

    E-Print Network [OSTI]

    US Army Corps of Engineers

    FARGO-MOORHEAD METROPOLITAN AREA, ND AND MN FLOOD RISK MANAGEMENT PROJECT 23 September 2011, and technically feasible flood risk management for Fargo, North Dakota, Moorhead, Minnesota, and the surrounding area, and a storage area to reduce the existing and future flood risk and damages to public and private

  4. Do Debris Flows Pose a Hazard to Mountain-Front Property in Metropolitan Phoenix, Arizona?

    E-Print Network [OSTI]

    Dorn, Ron

    Do Debris Flows Pose a Hazard to Mountain-Front Property in Metropolitan Phoenix, Arizona? Ronald I by growing suburbs of metropoli- tan Phoenix, Arizona, including on steep slopes above large single hazard in Phoenix and perhaps other grow- ing cities in the desert Southwest. Key Words: debris flow

  5. Generalizations of quantum statistics

    E-Print Network [OSTI]

    O. W. Greenberg

    2008-05-02

    We review generalizations of quantum statistics, including parabose, parafermi, and quon statistics, but not including anyon statistics, which is special to two dimensions.

  6. Computing and Introductory Statistics

    E-Print Network [OSTI]

    Kaplan, Daniel

    2007-01-01

    W. , (2007) “The Introductory Statistics Course: A PtolemaicTechnology Innovations in Statistics Education,1, Article 1.and Introductory Statistics Daniel T. Kaplan Macalester

  7. Statistical Software - Overview

    E-Print Network [OSTI]

    de Leeuw, Jan

    2010-01-01

    Review of Statistical Software. International As- sociationStatistical Methods Need Software: A View of Statisti- calJournal of Statistical Software, 13, 2004. URL http://www.

  8. Statistical Software - Overview

    E-Print Network [OSTI]

    Jan De Leeuw

    2011-01-01

    Review of Statistical Software. International As- sociationStatistical Methods Need Software: A View of Statisti- calJournal of Statistical Software, 13, 2004. URL http://www.

  9. Community air pollution and mortality: Analysis of 1980 data from US metropolitan areas. 1: Particulate air pollution

    SciTech Connect (OSTI)

    Lipfert, F.W.

    1992-11-01

    1980 data from up to 149 metropolitan areas were used to define cross-sectional associations between community air pollution and excess human mortality. The regression model proposed by Oezkaynak and Thurston, which accounted for age, race, education, poverty, and population density, was evaluated and several new models were developed. The new models also accounted for population change, drinking water hardness, and smoking, and included a more detailed description of race. Cause-of-death categories analyzed include all causes, all non-external causes, major cardiovascular diseases, and chronic obstructive pulmonary diseases (COPD). Both annual mortality rates and their logarithms were analyzed. The data on particulates were averaged across all monitoring stations available for each SMSA and the TSP data were restricted to the year 1980. The associations between mortality and air pollution were found to be dependent on the socioeconomic factors included in the models, the specific locations included din the data set, and the type of statistical model used. Statistically significant associations were found between TSP and mortality due to non-external causes with log-linear models, but not with a linear model, and between TS and COPD mortality for both linear and log-linear models. When the sulfate contribution to TSP was subtracted, the relationship with COPD mortality was strengthened. Scatter plots and quintile analyses suggested a TSP threshold for COPD mortality at around 65 ug/m{sup 3} (annual average). SO{sub 4}{sup {minus}2}, Mn, PM{sup 15}, and PM{sub 2.5} were not significantly associated with mortality using the new models.

  10. Response and Resistance to NF-?B Inhibitors in Mouse Models of Lung Adenocarcinoma

    E-Print Network [OSTI]

    Xue, Wen

    Lung adenocarcinoma is a leading cause of cancer death worldwide. We recently showed that genetic inhibition of the NF-?B pathway affects both the initiation and the maintenance of lung cancer, identifying this pathway as ...

  11. Requirement for NF-?B signalling in a mouse model of lung adenocarcinoma

    E-Print Network [OSTI]

    Meylan, Etienne

    NF-?B transcription factors function as crucial regulators of inflammatory and immune responses as well as of cell survival. They have also been implicated in cellular transformation and tumorigenesis. However, despite ...

  12. Interleukin-6 upregulates paraoxonase 1 gene expression via an AKT/NF-?B-dependent pathway

    SciTech Connect (OSTI)

    Cheng, Chi-Chih [Department of Research, Taichung Veterans General Hospital, Taichung, Taiwan (China)] [Department of Research, Taichung Veterans General Hospital, Taichung, Taiwan (China); Hsueh, Chi-Mei [Department of Life Sciences, National Chung Hsing University, Taichung, Taiwan (China)] [Department of Life Sciences, National Chung Hsing University, Taichung, Taiwan (China); Chen, Chiu-Yuan [Graduate Institute of Natural Healing Sciences, Nanhua University, Chiayi, Taiwan (China)] [Graduate Institute of Natural Healing Sciences, Nanhua University, Chiayi, Taiwan (China); Chen, Tzu-Hsiu, E-mail: hsiu@mail.chna.edu.tw [Department of Health and Nutrition, Chia Nan University of Pharmacy and Science, Tainan, Taiwan (China)] [Department of Health and Nutrition, Chia Nan University of Pharmacy and Science, Tainan, Taiwan (China); Hsu, Shih-Lan, E-mail: h2326@vghtc.gov.tw [Department of Research, Taichung Veterans General Hospital, Taichung, Taiwan (China) [Department of Research, Taichung Veterans General Hospital, Taichung, Taiwan (China); Department of Applied Chemistry, National Chi Nan University, Puli, Nantou, Taiwan (China)

    2013-07-19

    Highlights: •IL-6 could induce PON1 gene expression. •IL-6 increased NF-?B protein expression and NF-?B-p50 and -p65 subunits nuclear translocation. •IL-6-induced PON1 up-regulation was through an AKT/NF-?B pathway. -- Abstract: The aim of this study is to investigate the relationship between paraoxonase 1 (PON1) and atherosclerosis-related inflammation. In this study, human hepatoma HepG2 cell line was used as a hepatocyte model to examine the effects of the pro-inflammatory cytokines on PON1 expression. The results showed that IL-6, but not TNF-? and IL-1?, significantly increased both the function and protein level of PON1; data from real-time RT-PCR analysis revealed that the IL-6-induced PON1 expression occurred at the transcriptional level. Increase of I?B kinase activity and I?B phosphorylation, and reduction of I?B protein level were also observed in IL-6-treated HepG2 cells compared with untreated culture. This event was accompanied by increase of NF-?B-p50 and -p65 nuclear translocation. Moreover, treatment with IL-6 augmented the DNA binding activity of NF-?B. Furthermore, pharmacological inhibition of NF-?B activation by PDTC and BAY 11-7082, markedly suppressed the IL-6-mediated PON1 expression. In addition, IL-6 increased the levels of phosphorylated protein kinase B (PKB, AKT). An AKT inhibitor LY294002 effectively suppressed IKK/I?B/NF-?B signaling and PON1 gene expression induced by IL-6. Our findings demonstrate that IL-6 upregulates PON1 gene expression through an AKT/NF-?B signaling axis in human hepatocyte-derived HepG2 cell line.

  13. A test of first order scaling in Nf=2 QCD

    E-Print Network [OSTI]

    G. Cossu; M. D'Elia; A. Di Giacomo; C. Pica

    2007-09-30

    We complete our analysis of Nf=2 QCD based on the lattice staggered fermion formulation. Using a series of Monte Carlo simulations at fixed (amq*Ls^yh) one is able to test the universality class with given critical exponent yh. This strategy has been used to test the O(4) universality class and it has been presented at the previous Lattice conferences. No agreement was found with simulations in the mass range amq=[0.01335,0.15] using lattices with Ls=16 up to 32 and Lt=4. With the same strategy, we now investigate the possibility of a first order transition using a new set of Monte Carlo data corresponding to yh=3 in the same mass and volume range as the one used for O(4). A substantial agreement is observed both in the specific heat scaling and in the scaling of the chiral condensate, while the chiral susceptibilities still presents visible deviation from scaling in the mass range explored.

  14. The case for pension plan and university endowment equity investment in brownfields in the urban core of major metropolitan areas

    E-Print Network [OSTI]

    Larsen, Tamara C. (Tamara Candace), 1977-

    2003-01-01

    The purpose of this thesis is to present a case for institutional equity investment in brownfields in the urban core of major metropolitan areas. Pension plans and university endowments are the primary institutional investors ...

  15. In situ measurements of speciated atmospheric mercury and the identification of source regions in the Mexico City Metropolitan Area

    E-Print Network [OSTI]

    Rutter, A. P.

    In order to expand the currently limited understanding of atmospheric mercury source-receptor relationships in the Mexico City Metropolitan Area, real time measurements of atmospheric mercury were made at a downtown urban ...

  16. The effectiveness of jobs-housing balance as a strategy for reducing traffic congestion: a study of metropolitan Bangkok 

    E-Print Network [OSTI]

    Lobyaem, Sonchai

    2006-10-30

    Bangkok is widely known for its severe traffic congestion. The Thai government advocates the concept of jobs and housing balance (JHB) as a strategy for reducing traffic congestion in Metropolitan Bangkok. The basic idea is to decentralize the jobs...

  17. Chicago Metropolitan Agency for Planning Summary of Reported Data From July 1, 2010 - September 30, 2013

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:FinancingPetroleum Based Fuels|Programs |Chart of breakout of fundsChicago Metropolitan Agency for

  18. FISHERY STATISTICS UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES 1972 STATISTICAL DIGEST NO. 66 Prepared by STATISTICS;ACKNOWLEDGMENTS The data in this edition of "Fishery Statistics of the United States" were collected in co- operation with the various States and tabulated by the staff of the Statistics and Market News Division

  19. Development of NF3 Deposit Removal Technology for the Portsmouth Gaseous Diffusion Plant

    SciTech Connect (OSTI)

    Scheele, R.D.; McNamara, B.K.; Rapko, B.M.; Edwards, M.K.; Kozelisky, A.E.; Daniel, R.C. [Battelle Pacific Northwest Division, PO Box 999, Battelle Blvd, Richland, Washington 99352 (United States); McSweeney, T.I.; Maharas, S.J.; Weaver, P.J.; Iwamasa, K.J. [Battelle Columbus Operations, 505 King Avenue, Columbus, Ohio 43201 (United States); Kefgen, R.B. [WASTREN, Inc., 1864 Shyville Road, Piketon, Ohio 45661 (United States)

    2006-07-01

    This paper summarizes the Battelle, Stoller, and WASTREN (BSW) team's efforts, to date, in support of the United States Department of Energy's plans to remove uranium and technetium deposits before decommissioning the Portsmouth Gaseous Diffusion Plant. The BSW team investigated nitrogen trifluoride (NF{sub 3}) as a safer yet effective alternative gaseous treatment to the chlorine trifluoride (ClF{sub 3})-elemental fluorine (F{sub 2}) treatment currently used to remove uranium and technetium deposits from the uranium enrichment cascade. Both ClF{sub 3} and F{sub 2} are highly reactive, toxic, and hazardous gases, while NF{sub 3}, although toxic [1], is no more harmful than moth balls [2]. BSW's laboratory thermo-analytical and laboratory-scale prototype studies with NF{sub 3} established that thermal NF{sub 3} can effectively remove likely and potential uranium (UO{sub 2}F{sub 2} and UF{sub 4}) and technetium deposits (a surrogate deposit material, TcO{sub 2}, and pertechnetates) by conversion to volatile compounds. Our engineering evaluations suggest that NF{sub 3}'s effectiveness could be enhanced by combining with a lesser concentration of ClF{sub 3}. BSW's and other's studies indicate compatibility with Portsmouth materials of construction (aluminum, copper, and nickel). (authors)

  20. Regulation Of Nf=kb And Mnsod In Low Dose Radiation Induced Adaptive Protection Of Mouse And Human Skin Cells

    SciTech Connect (OSTI)

    Jian Li

    2012-11-07

    A sampling of publications resulting from this grant is provided. One is on the subject of NF-κB-Mediated HER2 Overexpression in Radiation-Adaptive Resistance. Another is on NF-κB-mediated adaptive resistance to ionizing radiation.

  1. CARD6 Is a Modulator of NF-B Activation by Nod1-and Cardiak-mediated Pathways*

    E-Print Network [OSTI]

    CARD6 Is a Modulator of NF- B Activation by Nod1- and Cardiak-mediated Pathways* Received specific binding of this CARD6-encoding protein to Nod1 (CARD4), Cardiak (Rip2/Rick), NAC (NALP1/DEFCAP implicated in NF- B and caspase-1 activation but not to other CARD family proteins. Cardiak and Nod1 (but

  2. NF-?B1 Inhibits TLR-Induced IFN-? Production in Macrophages Through TPL-2-dependent ERK Activation

    E-Print Network [OSTI]

    Yang, Huei-Ting

    Although NF-?B1 p50/p105 has critical roles in immunity, the mechanism by which NF-?B1 regulates inflammatory responses is unclear. In this study, we analyzed the gene expression profile of LPS-stimulated Nfkb1?/? macrophages ...

  3. Investigating the role of intra- and extra-cellular modulators of the transcription factor NF-kappaB

    E-Print Network [OSTI]

    Nguyen, Hung Nhat

    2011-01-01

    The nuclear factor-kappa B (NF-kappaB) family of transcription factors play a pivotal role in the inflammatory and immune responses, as well as cell growth and survival. Since its discovery 25 years ago, NF-kappaB has ...

  4. 1 Managed by UT-Battelle for the U.S. Department of Energy NF Splash Mitigation 12 July 2011

    E-Print Network [OSTI]

    McDonald, Kirk

    1 Managed by UT-Battelle for the U.S. Department of Energy NF Splash Mitigation 12 July 2011 for comparison & final determination #12;3 Managed by UT-Battelle for the U.S. Department of Energy NF Splash Neutrino Factory Mercury Pool Splash Mitigation V.B. Graves IDS Videoconference July 12, 2011 #12;2 Managed

  5. VALIDATION OF EAF-2010 (N,G) AND (N,F) REACTIONS 1. INTEGRAL ACTIVATION DATA BASE FOR (N,G) AND (N,F) REACTIONS

    E-Print Network [OSTI]

    VALIDATION OF EAF-2010 (N,G) AND (N,F) REACTIONS 1. INTEGRAL ACTIVATION DATA BASE FOR (N,G) AND (N IRRAGIAMENTO SIC A FNG, supplied by M Pillon used at FNG for integral exps [175 group Vitamin-E weighting Pillon used at FNG for integral exps [175 group Vitamin-E weighting]. UKAEA-FUS-547 7 fng_tung.asc 175

  6. Instruction sheet for the consolidation of the standard NF EN 693 dated September 2001 and its amendment A1 Machine tools : Safety : Hydraulic presses

    E-Print Network [OSTI]

    Association Française de Normalisation. Paris

    2009-01-01

    Instruction sheet for the consolidation of the standard NF EN 693 dated September 2001 and its amendment A1

  7. Sanders, J. E.; and Merguerian, Charles, 1992a, Directional history of Pleistocene glaciers inferred from features eroded on bedrock, New York metropolitan area, SE NY.

    E-Print Network [OSTI]

    Merguerian, Charles

    inferred from features eroded on bedrock, New York metropolitan area, SE NY. If a glacier erodes bedrock Tryon Park, Central Park, and in the New York Botanical Garden. To Cite This Abstract: Sanders, J. E on bedrock, New York metropolitan area, SE NY (abs.): Geological Society of America, Abstracts with Programs

  8. Microstructural Evolution in Two Variants of NF709 at 1023 and 1073 K

    E-Print Network [OSTI]

    Cambridge, University of

    and that could invalidate the extrapolations of short-term creep test data, and to identify any precipitates.K.D.H. BHADESHIA The microstructural state of two grades of the creep-resistant austenitic stainless steels NF709 regarded as one of the best austenitic steels for elevated temperature applications because of its creep

  9. Purinergic signaling is required for fluid shear stress-induced NF-{kappa}B translocation in osteoblasts

    SciTech Connect (OSTI)

    Genetos, Damian C., E-mail: dgenetos@ucdavis.edu [Department of Anatomy, Cell Biology, and Physiology, School of Veterinary Medicine, University of California, Davis, CA (United States); Karin, Norman J. [Cell Biology and Biochemistry, Pacific Northwest National Laboratory, Richland, WA (United States)] [Cell Biology and Biochemistry, Pacific Northwest National Laboratory, Richland, WA (United States); Geist, Derik J. [Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN (United States)] [Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN (United States); Donahue, Henry J. [Division of Musculoskeletal Sciences, Department of Orthopaedics and Rehabilitation, Pennsylvania State College of Medicine, Hershey, PA (United States)] [Division of Musculoskeletal Sciences, Department of Orthopaedics and Rehabilitation, Pennsylvania State College of Medicine, Hershey, PA (United States); Duncan, Randall L. [Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN (United States)] [Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN (United States)

    2011-04-01

    Fluid shear stress regulates gene expression in osteoblasts, in part by activation of the transcription factor NF-{kappa}B. We examined whether this process was under the control of purinoceptor activation. MC3T3-E1 osteoblasts under static conditions expressed the NF-{kappa}B inhibitory protein I{kappa}B{alpha} and exhibited cytosolic localization of NF-{kappa}B. Under fluid shear stress, I{kappa}B{alpha} levels decreased, and concomitant nuclear localization of NF-{kappa}B was observed. Cells exposed to fluid shear stress in ATP-depleted medium exhibited no significant reduction in I{kappa}B{alpha}, and NF-{kappa}B remained within the cytosol. Similar results were found using oxidized ATP or Brilliant Blue G, P2X{sub 7} receptor antagonists, indicating that the P2X{sub 7} receptor is responsible for fluid shear-stress-induced I{kappa}B{alpha} degradation and nuclear accumulation of NF-{kappa}B. Pharmacologic blockage of the P2Y6 receptor also prevented shear-induced I{kappa}B{alpha} degradation. These phenomena involved neither ERK1/2 signaling nor autocrine activation by P2X{sub 7}-generated lysophosphatidic acid. Our results suggest that fluid shear stress regulates NF-{kappa}B activity through the P2Y{sub 6} and P2X{sub 7} receptor.

  10. MDI-QKD: Continuous- versus discrete-variables at metropolitan distances

    E-Print Network [OSTI]

    Stefano Pirandola; Carlo Ottaviani; Gaetana Spedalieri; Christian Weedbrook; Samuel L. Braunstein; Seth Lloyd; Tobias Gehring; Christian S. Jacobsen; Ulrik L. Andersen

    2015-08-01

    In a comment, Xu, Curty, Qi, Qian, and Lo claimed that discrete-variable (DV) measurement device independent (MDI) quantum key distribution (QKD) would compete with its continuous-variable (CV) counterpart at metropolitan distances. Actually, Xu et al.'s analysis supports exactly the opposite by showing that the experimental rate of our CV protocol (achieved with practical room-temperature devices) remains one order of magnitude higher than their purely-numerical and over-optimistic extrapolation for qubits, based on nearly-ideal parameters and cryogenic detectors (unsuitable solutions for a realistic metropolitan network, which is expected to run on cheap room-temperature devices, potentially even mobile). The experimental rate of our protocol (expressed as bits per relay use) is confirmed to be two-three orders of magnitude higher than the rate of any realistic simulation of practical DV-MDI-QKD over short-medium distances. Of course this does not mean that DV-MDI-QKD networks should not be investigated or built, but increasing their rate is a non-trivial practical problem clearly beyond the analysis of Xu et al. Finally, in order to clarify the facts, we also refute a series of incorrect arguments against CV-MDI-QKD and, more generally, CV-QKD, which were made by Xu et al. with the goal of supporting their thesis.

  11. Interpreting Accident Statistics

    E-Print Network [OSTI]

    Ferreira, Joseph Jr.

    Accident statistics have often been used to support the argument that an abnormally small proportion of drivers account for a large proportion of the accidents. This paper compares statistics developed from six-year data ...

  12. EERE Statistics Archive

    Office of Energy Efficiency and Renewable Energy (EERE)

    This page provides EERE Web statistics for all office and corporate websites that opted to use EERE's analytics account. Webtrends statistics for Fiscal Year 2009 (FY09) to FY11 are available for...

  13. Web Analytics and Statistics

    Office of Energy Efficiency and Renewable Energy (EERE)

    EERE uses Google Analytics to capture statistics on its websites. These statistics help website managers measure and report on users, sessions, most visited pages, and more. The Web Template...

  14. Coal dust contiguity-induced changes in the concentration of TNF- and NF- B p65 on the ocular surface

    SciTech Connect (OSTI)

    Sun, Z.Y.; Hong, J.; Liu, Z.Y.; Jin, X.D.; Gu, C.H.

    2009-07-01

    To observe the influence of coal dust on ocular surface of coal miners and rabbits with coal dust contiguity on expression TNF- and NF- Bp65 and dry eye occurrence. Expression TNF- and NF- Bp65 in ocular surface were determined. Results showed tear production, BUT and lysozyme decreased for coal miners and rabbits with coal dust contiguity. Coal dust exposure was linked to development of xerophthalmia, and induced a higher expression of NF- B p65 and TNF- perhaps as a mechanism to resist coal dust ocular surface injury.

  15. MATHMATICS & APPLIED STATISTICS

    E-Print Network [OSTI]

    Frey, Jesse C.

    MATHMATICS & APPLIED STATISTICS Graduate Studies in Build Your Future with Graduate Study in Mathematics or Applied Statistics Our graduate programs can help you advance your career in education will deepen your knowledge and prepare you for further study. The Master of Science in Applied Statistics

  16. Statistics and Actuarial Science

    E-Print Network [OSTI]

    Chauve, Cedric

    SCIENCE SFU.CA/ SCIENCE Statistics and Actuarial Science #12;Further Information Student info, academic calendar, registration students.sfu.ca Science advising sfu.ca/science/undergrad/advising Statistics and Actuarial Science The Department of Statistics and Actuarial Science offers the degree

  17. Physics 630 Statistical Physics

    E-Print Network [OSTI]

    Kioussis, Nicholas

    strongly the issue of problem solving and understanding of the main concepts in Statistical PhysicsPhysics 630 Statistical Physics Spring 2005 Logistics Lecture Room: 1100 (Science I, 1st floor (Supplement) Introduction to Modern Statistical Mechanics, by David Chandler, Oxford Objectives This course

  18. Analysis and Comparison between War Driving and War Walk-ing in Metropolitan WiFi Radio Maps

    E-Print Network [OSTI]

    Chu, Hao-hua

    Analysis and Comparison between War Driving and War Walk- ing in Metropolitan WiFi Radio Maps Arvin, Hsinchu County, 310, Taiwan arvin@itri.org.tw ABSTRACT War-driving is currently the most widely adopted cost for war driv- ing is smaller than that of war walking, its positional accu- racy is also lower

  19. An Investigation into the Spatial Variability of Near-Surface Air Temperatures in the Detroit, Michigan, Metropolitan Region*

    E-Print Network [OSTI]

    Brown, Daniel G.

    An Investigation into the Spatial Variability of Near-Surface Air Temperatures in the Detroit. This study focused on the air temperatures in the Detroit, Michigan, metropolitan region during the summer portions of Detroit experienced decreased temperatures during afternoons. 1. Introduction In 2010, more

  20. Natural Proteasome Inhibitor Celastrol Suppresses Androgen-Independent Prostate Cancer Progression by Modulating Apoptotic Proteins and NF-kappaB

    E-Print Network [OSTI]

    Dai, Yao; Jeffrey, Tang; Wenhua, Xiaojie; Meng, Yang; Burstein, Ezra; Lawrence, Theodore S.; Xu, Liang

    2010-12-10

    Background Celastrol is a natural proteasome inhibitor that exhibits promising anti-tumor effects in human malignancies, especially the androgen-independent prostate cancer (AIPC) with constitutive NF-?B activation. ...

  1. Linear noise approximation of noise-induced oscillation in NF-?B signaling network

    E-Print Network [OSTI]

    Jaewook Joo

    2010-10-08

    NF-{\\kappa}B, one of key regulators of inflammation, apoptosis, and differentiation, was found to have noisy oscillatory shuttling between the nucleus and the cytoplasm in single cells when cells are stimulated by cytokine TNF{\\alpha}. We present the analytical analysis which uncovers the underlying physical mechanisms of this spectacular noise-induced transition in biological networks. Starting with the master equation describing both signaling and transcription events in NF-{\\kappa}B signaling network, we derived the macroscopic and the Fokker-Planck equations by using van Kampen's sysem size expansion. Using the noise-induced oscillatory signatures present in the power spectrum, we constructed the two-dimensional phase diagram where the noise-induced oscillation emerges in the dynamically stable parameter space.

  2. Omentin inhibits TNF-{alpha}-induced expression of adhesion molecules in endothelial cells via ERK/NF-{kappa}B pathway

    SciTech Connect (OSTI)

    Zhong, Xia, E-mail: zhongxia1977@126.com [Department of Emergency, Provincial Hospital Affiliated to Shandong University, Jinan 250021 (China)] [Department of Emergency, Provincial Hospital Affiliated to Shandong University, Jinan 250021 (China); Li, Xiaonan; Liu, Fuli; Tan, Hui [Department of Emergency, Provincial Hospital Affiliated to Shandong University, Jinan 250021 (China)] [Department of Emergency, Provincial Hospital Affiliated to Shandong University, Jinan 250021 (China); Shang, Deya, E-mail: wenhuashenghuo1@163.com [Department of Emergency, Provincial Hospital Affiliated to Shandong University, Jinan 250021 (China)] [Department of Emergency, Provincial Hospital Affiliated to Shandong University, Jinan 250021 (China)

    2012-08-24

    Highlights: Black-Right-Pointing-Pointer Omentin inhibited TNF-{alpha}-induced adhesion of THP-1 cells to HUVECs. Black-Right-Pointing-Pointer Omentin reduces expression of ICAM-1 and VCAM-1 induced by TNF-{alpha} in HUVECs. Black-Right-Pointing-Pointer Omentin inhibits TNF-{alpha}-induced ERK and NF-{kappa}B activation in HUVECs. Black-Right-Pointing-Pointer Omentin supreeses TNF-{alpha}-induced expression of ICAM-1 and VCAM-1 via ERK/NF-{kappa}B pathway. -- Abstract: In the present study, we investigated whether omentin affected the expression of intracellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) in tumor necrosis factor-{alpha} (TNF-{alpha}) induced human umbilical vein endothelial cells (HUVECs). Our data showed that omentin decreased TNF-{alpha}-induced expression of ICAM-1 and VCAM-1 in HUVECs. In addition, omentin inhibited TNF-{alpha}-induced adhesion of THP-1 cells to HUVECs. Further, we found that omentin inhibited TNF-{alpha}-activated signal pathway of nuclear factor-{kappa}B (NF-{kappa}B) by preventing NF-{kappa}B inhibitory protein (I{kappa}B{alpha}) degradation and NF-{kappa}B/DNA binding activity. Omentin pretreatment significantly inhibited TNF-{alpha}-induced ERK activity and ERK phosphorylation in HUVECs. Pretreatment with PD98059 suppressed TNF-{alpha}-induced NF-{kappa}B activity. Omentin, NF-kB inhibitor (BAY11-7082) and ERK inhibitor (PD98059) reduced the up-regulation of ICAM-1 and VCAM-1 induced by TNF-{alpha}. These results suggest that omentin may inhibit TNF-{alpha}-induced expression of adhesion molecules in endothelial cells via blocking ERK/NF-{kappa}B pathway.

  3. Key China Energy Statistics 2011

    E-Print Network [OSTI]

    Levine, Mark

    2013-01-01

    Source: National Bureau of Statistics (NBS), China EnergyNations Commodity Trade Statistics Database. New York:National Bureau of Statistics of the People's Republic of

  4. Key China Energy Statistics 2012

    E-Print Network [OSTI]

    Levine, Mark

    2013-01-01

    Nations Commodity Trade Statistics Database. New York:National Bureau of Statistics of the People's Republic ofYearbook. Beijing: China Statistics Press. 2. Transformation

  5. Statistics and the Modern Student

    E-Print Network [OSTI]

    Robert Gould

    2011-01-01

    Technology Innovations in Statistics Education, 3(1). Wild,the "wider view" of statistics, The American Statistician,a History of Teaching Statistics, Edinburgh: John Bibby (

  6. Statistics and the Modern Student

    E-Print Network [OSTI]

    Gould, Robert

    2010-01-01

    Technology Innovations in Statistics Education, 3(1). Wild,the "wider view" of statistics, The American Statistician,a History of Teaching Statistics, Edinburgh: John Bibby (

  7. Agreement Execution Process Study: CRADAs and NF-WFO Agreements and the Speed of Business

    SciTech Connect (OSTI)

    Harrer, Bruce J.; Cejka, Cheryl L.; Macklin, Richard; Miksovic, Ann

    2011-02-01

    This report summarizes the findings of a study on the execution of Cooperative Research and Development Agreements (CRADAs) and Non-Federal Work for Others (NF-WFO) agreements across the U.S. Department of Energy (DOE) laboratory complex. The study provides quantitiative estimates of times required to negotiate and execute these agreements across the DOE complex. It identifies factors impacting on cycle times and describes best practicies used at various laboratories and site offices that reduce cycle times.

  8. MC/NF TARGET SHIELDING STUDIES. NICHOLAS SOUCHLAS (10/29/2010)

    E-Print Network [OSTI]

    McDonald, Kirk

    MC/NF TARGET SHIELDING STUDIES. NICHOLAS SOUCHLAS (10/29/2010) 1 #12;Energy deposition from MARS, MARS+MCNP codes. STANDARD (STUDY II) GEOMETRY. STANDARD SHIELDING (80%WC+20% H2O). 4MW proton beamW to 50 kW in total power. 4 24 GeV 8 GeV #12;OFF/ON SHIELDING, DIFFERENT NEUTRON ENERGY CUTOFFS. 5 #12

  9. Statistics 221 Statistical Computing Methods Instructor: Mark Irwin

    E-Print Network [OSTI]

    Irwin, Mark E.

    Linear algebra, Statistics 111, and knowledge of a computer programming language. Statistics 220 (1988). Elements of Statistical Computing: Numerical Computation. CRC Press. Splus / R: Venables WNStatistics 221 ­ Statistical Computing Methods Instructor: Mark Irwin Office: Science Center 235

  10. 1 Statistics Statistics plays an important role throughout society, providing

    E-Print Network [OSTI]

    Vertes, Akos

    1 Statistics STATISTICS Statistics plays an important role throughout society, providing data. They also explore how those skills can be applied to develop new initiatives. Statistics is one. UNDERGRADUATE Bachelor's program · Bachelor of Science with a major in statistics (http:// bulletin.gwu.edu/arts-sciences/statistics

  11. Statistics and Quantum Chaos

    E-Print Network [OSTI]

    F. Benatti; M. Fannes

    1998-11-26

    We use multi-time correlation functions of quantum systems to construct random variables with statistical properties that reflect the degree of complexity of the underlying quantum dynamics.

  12. Rotations and Statistics

    E-Print Network [OSTI]

    Kevin Cahill

    2006-12-24

    The way a field transforms under rotations determines its statistics--as is easy to see for scalar, Dirac, and vector fields.

  13. Edinburgh Research Explorer Statistical Constraints

    E-Print Network [OSTI]

    Millar, Andrew J.

    Edinburgh Research Explorer Statistical Constraints Citation for published version: Rossi, R that links statistics and constraint programming. We dis- cuss two novel statistical constraints and some, Prestwich, S & Tarim, SA 2014, 'Statistical Constraints' Paper presented at 21st biennial European

  14. Weakly sufficient quantum statistics

    E-Print Network [OSTI]

    Katarzyna Lubnauer; Andrzej ?uczak; Hanna Pods?dkowska

    2009-11-23

    Some aspects of weak sufficiency of quantum statistics are investigated. In particular, we give necessary and sufficient conditions for the existence of a weakly sufficient statistic for a given family of vector states, investigate the problem of its minimality, and find the relation between weak sufficiency and other notions of sufficiency employed so far.

  15. Statistics Statistique Canada Canada

    E-Print Network [OSTI]

    Canada Développement social Canada Culture,Tourism and the Centre for Education Statistics Doctoral, Tourism and the Centre for Education Statistics Division Main Building, Room 2001, Ottawa, K1A 0T6 to access the product This product, Catalogue no. 81-595-M, is available for free in electronic format

  16. 1 Managed by UT-Battelle for the U.S. Department of Energy NF/IDS Hg Vessel Layout 30 Jun 09

    E-Print Network [OSTI]

    McDonald, Kirk

    1 Managed by UT-Battelle for the U.S. Department of Energy NF/IDS Hg Vessel Layout 30 Jun 09;3 Managed by UT-Battelle for the U.S. Department of Energy NF/IDS Hg Vessel Layout 30 Jun 09 Cross Section to flow out the front of the cryostat #12;4 Managed by UT-Battelle for the U.S. Department of Energy NF

  17. Statistics of football dynamics

    E-Print Network [OSTI]

    Mendes, R S; Anteneodo, C

    2007-01-01

    We investigate the dynamics of football matches. Our goal is to characterize statistically the temporal sequence of ball movements in this collective sport game, searching for traits of complex behavior. Data were collected over a variety of matches in South American, European and World championships throughout 2005 and 2006. We show that the statistics of ball touches presents power-law tails and can be described by $q$-gamma distributions. To explain such behavior we propose a model that provides information on the characteristics of football dynamics. Furthermore, we discuss the statistics of duration of out-of-play intervals, not directly related to the previous scenario.

  18. Statistics 36-756: Advanced Statistics II Syllabus: Fall, 2006

    E-Print Network [OSTI]

    Fienberg, Stephen E.

    Statistics 36-756: Advanced Statistics II Syllabus: Fall, 2006 Instructor: Stephen E. Fienberg 132G: · To consider major topics from statistical theory and the foundations of inference not covered in Statistics 36-756: Advanced Statistics I, such as exchangeability, the axiomatic foundation of subjective probability

  19. IDS-NF Impact of Neutrino Cross Section Impact of Neutrino Cross Section

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverse (JournalvivoHighHussein KhalilResearch &ENERGYWhoCELL WALLS4,IDRMSIDS-NF

  20. Computational Statistics Canonical Forest

    E-Print Network [OSTI]

    Ahn, Hongshik

    : First Author: Yu-Chuan Chen First Author Secondary Information: Order of Authors: Yu-Chuan Chen Hyejung;Computational Statistics manuscript No. (will be inserted by the editor) Canonical Forest Yu-Chuan Chen

  1. Statistics in Excel

    E-Print Network [OSTI]

    Dave

    2012-03-25

    Statistics in Excel. 1. Type the measurement data into consecutive cells in Excel. NOTE: they do not need to be in one column, but the cells should be adjacent.

  2. Boosted Statistical Mechanics

    E-Print Network [OSTI]

    Massimo Testa

    2015-07-30

    Based on the fundamental principles of Relativistic Quantum Mechanics, we give a rigorous, but completely elementary, proof of the relation between fundamental observables of a statistical system when measured relatively to two inertial reference frames, connected by a Lorentz transformation.

  3. Springer Series in Statistics Springer Series in Statistics

    E-Print Network [OSTI]

    Cappé, Olivier

    and practitioners in areas such as statistics, signal processing, communications engineering, control theory class of statistical models with applications in diverse areas such as communications engineering models, including both algo- rithms and statistical theory. Topics range from filtering and smoothing

  4. ARNAB MAITY Department of Statistics

    E-Print Network [OSTI]

    Maity, Arnab

    Mallick 2003 B. Stat. (Honors), Statistics, Indian Statistical Institute, Calcutta, India First classMay, 2015 ARNAB MAITY Department of Statistics North Carolina State University Campus Box 8203 2008 Ph.D., Statistics, Department of Statistics, Texas A&M University Co-advisors: Dr. Raymond J

  5. FISHERY STATISTICS E UNITED STATES

    E-Print Network [OSTI]

    SH 11 .A443X FISH FISHERY STATISTICS E UNITED STATES ^ 1951 &ch 3. \\§^ ^/'· m:^ STATISTICAL DIGEST. Farley, Director Statistical Digest 30 FISHERY STATISTICS OF THE UNITED STATES 1951 BY A. W. ANDERSON;Fishery Statistics of the United States and Alaska are compiled and published annually to make available

  6. FY13 Summary Report on the Augmentation of the Spent Fuel Composition Dataset for Nuclear Forensics: SFCOMPO/NF

    SciTech Connect (OSTI)

    Brady Raap, Michaele C.; Lyons, Jennifer A.; Collins, Brian A.; Livingston, James V.

    2014-03-31

    This report documents the FY13 efforts to enhance a dataset of spent nuclear fuel isotopic composition data for use in developing intrinsic signatures for nuclear forensics. A review and collection of data from the open literature was performed in FY10. In FY11, the Spent Fuel COMPOsition (SFCOMPO) excel-based dataset for nuclear forensics (NF), SFCOMPO/NF was established and measured data for graphite production reactors, Boiling Water Reactors (BWRs) and Pressurized Water Reactors (PWRs) were added to the dataset and expanded to include a consistent set of data simulated by calculations. A test was performed to determine whether the SFCOMPO/NF dataset will be useful for the analysis and identification of reactor types from isotopic ratios observed in interdicted samples.

  7. BS in STATISTICS: Statistical Science Emphasis (695220) MAP Sheet Department of Statistics

    E-Print Network [OSTI]

    Dahl, David B.

    : Statistics Stat 497R Introduction to Statistical Research Stat 538 Survival Analysis Note: Students may countBS in STATISTICS: Statistical Science Emphasis (695220) MAP Sheet Department of Statistics & Oral Communication Quantitative Reasoning Languages of Learning (Math or Language) Arts, Letters

  8. ABD56 causes osteoclast apoptosis by inhibiting the NF{kappa}B and ERK pathways

    SciTech Connect (OSTI)

    Idris, Aymen [Rheumatic Diseases Unit, Molecular Medicine Centre, University of Edinburgh, General Western Hospital, Edinburgh, EH4 2XU (United Kingdom); Mrak, Emanuela [Bone Metabolic Unit, Scientific Institute H San Raffaele, via Olgettina 60, 20132 Milano (Italy); Department of Pharmacology, Chemotherapy and Medical Toxicology, University of Milano, via Vanvitelli 32, 20129 Milano (Italy); Greig, Iain [Department of Medicine and Therapeutics, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD (United Kingdom); Guidobono, Francesca [Department of Pharmacology, Chemotherapy and Medical Toxicology, University of Milano, via Vanvitelli 32, 20129 Milano (Italy); Ralston, Stuart H. [Rheumatic Diseases Unit, Molecular Medicine Centre, University of Edinburgh, General Western Hospital, Edinburgh, EH4 2XU (United Kingdom); Hof, Rob van 't [Rheumatic Diseases Unit, Molecular Medicine Centre, University of Edinburgh, General Western Hospital, Edinburgh, EH4 2XU (United Kingdom)], E-mail: rvanthof@staffmail.ed.ac.uk

    2008-06-20

    We have previously shown that the biphenylcarboxylic acid butanediol ester (ABD56) inhibits osteoclast formation and activity in vitro and in vivo. However, the mechanism of action of this compound is unknown. ABD56 inhibited osteoclast formation and caused osteoclast apoptosis, but had no effects on osteoblasts or macrophages. As the NF{kappa}B and MAPK pathways are essential for osteoclast formation and survival, we studied the effects of ABD56 on these pathways. ABD56 caused phosphorylation of p38, JNK and nuclear translocation of c-jun in osteoclasts. ABD56-induced apoptosis was prevented by the caspase inhibitor zVAD-fmk but was not prevented by the p38- or JNK-inhibitors. ABD56 completely abolished RANKL-induced I{kappa}B and ERK1/2 phosphorylation. Increasing the amount of RANKL partially rescued ABD56-induced apoptosis, indicating that the apoptosis is most probably due to the inhibition of survival signals such as ERK and NF{kappa}B, rather than activation of the p38 or Jnk MAPK pathways.

  9. Quantum Chaos and Statistical Mechanics

    E-Print Network [OSTI]

    Mark Srednicki

    1994-06-14

    We briefly review the well known connection between classical chaos and classical statistical mechanics, and the recently discovered connection between quantum chaos and quantum statistical mechanics.

  10. Statistics and Differential Geometry 18-466 Mathematical Statistics

    E-Print Network [OSTI]

    Le Ny, Jerome

    Statistics and Differential Geometry 18-466 Mathematical Statistics Jerome Le Ny December 14, 2005 of statistical curvature [Efr75], that most of the main concepts and methods of differ- ential geometry are of substantial interest in connection with the theory of statistical inference. This report describes in simple

  11. 55 Years of Harvard Statistics: Stories, Snapshots, and Statistics

    E-Print Network [OSTI]

    Wolfe, Patrick J.

    55 Years of Harvard Statistics: Stories, Snapshots, and Statistics Xiao-Li Meng Late evening instead to the Bell Telephone Laboratories.'' Having one's statistical research rooted in and moti- vated by real-life applications became a hallmark of Harvard Statistics' outlook (or ``departmentality'') from

  12. Experimental Statistics NBS Handbook 91: Experimental Statistics [1] was

    E-Print Network [OSTI]

    Experimental Statistics NBS Handbook 91: Experimental Statistics [1] was first published in 1963 as a series of five Army Ordnance Pamphlets OSRDDP 20-110-114. The publication was prepared in the Statistical. Basic Statistical Concepts and Analysis and Inter- pretation of Measurement Data 2. Standard Techniques

  13. MATHEMATICS AND STATISTICS

    E-Print Network [OSTI]

    Banaji,. Murad

    MATHEMATICS AND STATISTICS Canterbury The UK's European university Undergraduate study #12;2 ACADEMIC EXCELLENCE AND INSPIRATIONAL TEACHING Much of science is based upon the application of mathematics as for computer science. New discoveries within mathematics affect not only science, but also our general

  14. Thermodynamics for Fractal Statistics

    E-Print Network [OSTI]

    Wellington da Cruz

    1998-12-15

    We consider for an anyon gas its termodynamics properties taking into account the fractal statistics obtained by us recently. This approach describes the anyonic excitations in terms of equivalence classes labeled by fractal parameter or Hausdorff dimension $h$. An exact equation of state is obtained in the high-temperature and low-temperature limits, for gases with a constant density of states.

  15. Statistical Methods for QTL

    E-Print Network [OSTI]

    Chen, Zehua

    , researchers, and professionals in the mathematical, statistical and computational sciences, fundamental of textbooks, reference works, and handbooks. The titles included in the series are meant to appeal to students Editors N. F. Britton Department of Mathematical Sciences University of Bath Xihong Lin Department

  16. Journal of Membrane Science 256 (2005) 134142 Characterization of novel acid-stable NF membranes before and after

    E-Print Network [OSTI]

    Freger, Viatcheslav "Slava"

    2005-01-01

    to hot 20% sulfuric acid solutions for various times. Swelling and morphological changes measured Nanofiltration (NF) membranes represent a class of mem- branes with capabilities to selectively separate low- sulfone, which support an ultra-thin selective layer a few tens to a few hundred of nanometers thick

  17. Mast cell chymase induces smooth muscle cell apoptosis by disrupting NF-{kappa}B-mediated survival signaling

    SciTech Connect (OSTI)

    Leskinen, Markus J. [Wihuri Research Institute, Kalliolinnantie 4, FI-00140 Helsinki (Finland); Heikkilae, Hanna M. [Wihuri Research Institute, Kalliolinnantie 4, FI-00140 Helsinki (Finland); Speer, Mei Y. [Bioengineering Department, University of Washington, Seattle, WA 98195 (United States); Hakala, Jukka K. [Wihuri Research Institute, Kalliolinnantie 4, FI-00140 Helsinki (Finland); Laine, Mika [Department of Medicine, Helsinki University Central Hospital and Minerva Institute for Medical Research, Helsinki (Finland); Kovanen, Petri T. [Wihuri Research Institute, Kalliolinnantie 4, FI-00140 Helsinki (Finland); Lindstedt, Ken A. [Wihuri Research Institute, Kalliolinnantie 4, FI-00140 Helsinki (Finland)]. E-mail: ken.lindstedt@wri.fi

    2006-05-01

    Chymase released from activated mast cells induces apoptosis of vascular smooth muscle cells (SMCs) in vitro by degrading the pericellular matrix component fibronectin, so causing disruption of focal adhesion complexes and Akt dephosphorylation, which are necessary for cell adhesion and survival. However, the molecular mechanisms of chymase-mediated apoptosis downstream of Akt have remained elusive. Here, we show by means of RT-PCR, Western blotting, EMSA, immunocytochemistry and confocal microscopy, that chymase induces SMC apoptosis by disrupting NF-{kappa}B-mediated survival signaling. Following chymase treatment, the translocation of active NF-{kappa}B/p65 to the nucleus was partly abolished and the amount of nuclear p65 was reduced. Pretreatment of SMCs with chymase also inhibited LPS- and IL-1{beta}-induced nuclear translocation of p65. The chymase-induced degradation of p65 was mediated by active caspases. Loss of NF-{kappa}B-mediated transactivation resulted in downregulation of bcl-2 mRNA and protein expression, leading to mitochondrial swelling and release of cytochrome c. The apoptotic process involved activation of both caspase 9 and caspase 8. The results reveal that, by disrupting the NF-{kappa}B-mediated survival-signaling pathway, activated chymase-secreting mast cells can mediate apoptosis of cultured arterial SMCs. Since activated mast cells colocalize with apoptotic SMCs in vulnerable areas of human atherosclerotic plaques, they may participate in the weakening and rupture of atherosclerotic plaques.

  18. Genome-wide scan reveals association of psoriasis with IL-23 and NF-kB pathways

    E-Print Network [OSTI]

    Abecasis, Goncalo

    Genome-wide scan reveals association of psoriasis with IL-23 and NF-kB pathways Rajan P Nair1 Abecasis4,20, for the Collaborative Association Study of Psoriasis18 Psoriasis is a common immune-mediated disorder that affects the skin, nails and joints. To identify psoriasis susceptibility loci, we genotyped

  19. Modeling green fluorescent protein transcription, translation and modification as a method to obtain NF-kappaB activation profiles 

    E-Print Network [OSTI]

    Laible, Allyson Marie

    2009-05-15

    that fluorescence increases up to 24 hours after an initial delay of approximately four hours. The fluorescence data was also used to develop a model describing significant events leading to NF-?B activation and GFP expression. In addition, a model describing...

  20. Decreasing NF-?B Expression Enhances Odontoblastic Differentiation and Collagen Expression in Dental Pulp Stem Cells Exposed to Inflammatory Cytokines 

    E-Print Network [OSTI]

    Hozhabri, Neda S. T.; Benson, M. Douglas; Vu, Michael D.; Patel, Rinkesh H.; Martinez, Rebecca M.; Nakhaie, Fatemeh N.; Kim, Harry K. W.; Varanasi, Venu G.

    2015-01-28

    Decreasing NF-?B Expression Enhances Odontoblastic Differentiation and Collagen Expression in Dental Pulp Stem Cells Exposed to Inflammatory Cytokines Neda S. T. Hozhabri1, M. Douglas Benson1, Michael D. Vu1, Rinkesh H. Patel1, Rebecca M. Martinez1, Fatemeh N...

  1. Ascorbic acid suppresses endotoxemia and NF-?B signaling cascade in alcoholic liver fibrosis in guinea pigs: A mechanistic approach

    SciTech Connect (OSTI)

    Abhilash, P.A.; Harikrishnan, R.; Indira, M.

    2014-01-15

    Alcohol consumption increases the small intestinal bacterial overgrowth (SIBO) and intestinal permeability of endotoxin. The endotoxin mediated inflammatory signaling plays a major role in alcoholic liver fibrosis. We evaluated the effect of ascorbic acid (AA), silymarin and alcohol abstention on the alcohol induced endotoxemia and NF-?B activation cascade pathway in guinea pigs (Cavia porcellus). Guinea pigs were administered ethanol at a daily dose of 4 g/kg b.wt for 90 days. After 90 days, ethanol administration was stopped. The ethanol treated animals were divided into abstention, silymarin (250 mg/kg b.wt) and AA (250 mg/kg b.wt) supplemented groups and maintained for 30 days. The SIBO, intestinal permeability and endotoxin were significantly increased in the ethanol group. The mRNA expressions of intestinal proteins claudin, occludin and zona occludens-1 were significantly decreased in ethanol group. The mRNA levels of inflammatory receptors, activity of IKK? and the protein expressions of phospho-I?B?, NF-?B, TNF-?, TGF-?{sub 1} and IL-6 were also altered in ethanol group. The expressions of fibrosis markers ?-SMA, ?{sub 1} (I) collagen and sirius red staining in the liver revealed the induction of fibrosis. But the supplementation of AA could induce greater reduction of ethanol induced SIBO, intestinal barrier defects, NF-?B activation and liver fibrosis than silymarin. The possible mechanism may be the inhibitory effect of AA on SIBO, intestinal barrier defect and IKK?, which decreased the activation of NF-?B and synthesis of cytokines. This might have led to suppression of HSCs activation and liver fibrosis. - Highlights: • Alcohol increases intestinal bacterial overgrowth and permeability of endotoxin. • Endotoxin mediated inflammation plays a major role in alcoholic liver fibrosis. • Ascorbic acid reduces endotoxemia, NF-?B activation and proinflammatory cytokines. • AA's action is by inhibition of SIBO, IKK? and alteration of intestinal permeability. • This might have led to suppression of HSCs activation and liver fibrosis.

  2. BS in STATISTICS: Applied Statistics and Analytics Emphasis (695234) MAP Sheet Department of Statistics

    E-Print Network [OSTI]

    Dahl, David B.

    BS in STATISTICS: Applied Statistics and Analytics Emphasis (695234) MAP Sheet Department of Statistics For students entering the degree program during the 2014­2015 curricular year. UNIVERSITY CORE* Calculus 1 Math 113 Calculus 2 Complete one course from the following: Stat 121 Principles of Statistics

  3. BS in STATISTICS: Statistical Science Emphasis (695220) MAP Sheet Department of Statistics

    E-Print Network [OSTI]

    Seamons, Kent E.

    the statistics list: C S 142 Introduction to Computer Programming Math 334 Ordinary Differential Equations Math Academic Internship: Statistics Stat 497R Introduction to Statistical Research Stat 535 Applied Linear are strongly recommended to choose electives to prepare for the BYU BS/MS statistics integrated program

  4. AMERICAN STATISTICAL ASSOCIATION (ASA)

    U.S. Energy Information Administration (EIA) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page| Open Energy Informationmonthly gasoline price to fall toUranium Marketing Annual ReportAMERICAN STATISTICAL

  5. Statistical simulation procedures 

    E-Print Network [OSTI]

    Tremelling, Robert Norman

    1970-01-01

    that theoretical procedures are im- practical. Thus, with the advent of the electronic computer, numeri ca'I or simul ation procedures for ap- proximating this distribution function have been de- veloped. For the extension of the Stratified Monte Carlo (S. M... distribution functions ano their parameters. With the rising importance of statistics, and the advent of the computer, Honte Carlo methods are just now being investigated. Although definitions of Honte Carlo samplino may differ, it is usually associated...

  6. FY 2013 Statistical Table

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative Fuelsof Energy Services » Program ManagementAct FAQsAnnualAnnualHawaiiStatistical

  7. Pseudochaos in Statistical Physics

    E-Print Network [OSTI]

    Boris Chirikov

    1997-04-30

    A new generic dynamical phenomenon of pseudochaos and its relevance to the statistical physics both modern as well as traditional one are considered and explained in some detail. The pseudochaos is defined as a statistical behavior of the dynamical system with discrete energy and/or frequency spectrum. In turn, the statistical behavior is understood as time-reversible but nonrecurrent relaxation to some steady state, at average, superimposed with irregular fluctuations. The main attention is payed to the most important and universal example of pseudochaos, the so-called quantum chaos that is dynamical chaos in bounded mesoscopic quantum systems. The quantum chaos as a mechanism for implementation of the fundamental correspondence principle is also discussed. The quantum relaxation localization, a peculiar characteristic implication of pseudochaos, is reviewed in both time-dependent and conservative systems with special emphasis on the dynamical decoherence of quantum chaotic states. Recent results on the peculiar global structure of the energy shell, the Green function spectra and the eigenfunctions, both localized and ergodic, in a generic conservative quantum system are presented. Examples of pseudochaos in classical systems are given including linear oscillator and waves, digital computer and completely integrable systems. A far-reaching similarity between the dynamics of a few-freedom quantum system at high energy levels (n >> 1) and that of many--freedom one (N >> 1) is also discussed.

  8. Chemical evolution of volatile organic compounds in the outflow of the Mexico City Metropolitan area

    SciTech Connect (OSTI)

    Apel, Eric; Emmons, L.; Karl, Thomas G.; Flocke, Frank M.; Hills, A. J.; Madronich, Sasha; Lee-Taylor, J.; Fried, Alan; Weibring, P.; Walega, J.; Richter, Dirk; Tie, X.; Mauldin, L.; Campos, Teresa; Weinheimer, Andrew J.; Knapp, David; Sive, B.; Kleinman, Lawrence I.; Springston, S.; Zaveri, Rahul A.; Ortega, John V.; Voss, Paul B.; Blake, D. R.; Baker, Angela K.; Warneke, Carsten; Welsh-Bon, Daniel; de Gouw, Joost A.; Zheng, J.; Zhang, Renyi; Rudolph, Jochen; Junkermann, W.; Riemer, D.

    2010-01-01

    The volatile organic compound (VOC) distribution in the Mexico City Metropolitan Area (MCMA) and its evolution as it is uplifted and transported out of the MCMA basin was studied during the 2006 MILAGRO/MIRAGE-Mex field campaign. The results show that in the morning hours in the city center, the VOC distribution is dominated by non-methane hydrocarbons (NMHCs) but with a substantial contribution from oxygenated volatile organic compounds (OVOCs), predominantly from primary emissions. Alkanes account for a large part of the NMHC distribution in terms of mixing ratios. In terms of reactivity, NMHCs also dominate overall, especially in the morning hours. However, in the afternoon, as the boundary layer lifts and air is mixed and aged within the basin, the distribution changes as secondary products are formed. The WRF-Chem (Weather Research and Forecasting with Chemistry) model and MOZART (Model for Ozone and Related chemical Tracers) were able to reproduce the general features of the daytime cycle of the VOC OH reactivity distribution showing that NMHCs dominate the distribution except in the afternoon hours and that the VOC OH reactivity peaks in the early morning due to high morning emissions from the city into a shallow boundary layer. The WRF-Chem and MOZART models showed higher reactivity than the experimental data during the nighttime cycle, perhaps indicating problems with the modeled nighttime boundary layer height. In addition, a plume was studied in which air was advected out of the MCMA and intercepted downwind with the DOE G1 on March 18 and the NCAR C130 one day later on March 19. A number of identical species measured aboard each aircraft gave insight into the chemical evolution of the plume as it aged and was transported as far as 1000 km downwind. Ozone and many OVOCs were photochemically produced in the plume. The WRF-Chem and MOZART models were used to examine the spatial and temporal extent of the March 19 plume and to help interpret the OH reactivity in the downwind plume. The model results generally showed good agreement with experimental results for the total VOC OH reactivity downwind and gave insight into the distributions of VOC chemical classes downwind. A box model with detailed gas phase chemistry (NCAR Master Mechanism), initialized with concentrations observed at one of the ground sites in the MCMA, was used to examine the expected evolution of specific VOCs over a 1-2 day period. The models clearly supported the experimental evidence for NMHC oxidation leading to the formation of OVOCs downwind, which then become the primary fuel for ozone production far away from the MCMA.

  9. Chemical evolution of volatile organic compounds in the outflow of the Mexico City Metropolitan area

    SciTech Connect (OSTI)

    Apel, E.; Springston, S.; Karl, T.; Emmons, L.; Flocke, F.; Hills, A. J.; Madronich, S.; Lee-Taylor, J.; Fried, A.; Weibring, P.; Walega, J.; Richter, D., Tie, X.; Mauldin, L.; Campos, T.; Sive, B.; Kleinman, L.; Springston, S., Zaveri, R.; deGouw, J.; Zheng, J.; Zhang, R.; Rudolph, J.; Junkermann, W.; Riemer, D. D.

    2009-11-01

    The volatile organic compound (VOC) distribution in the Mexico City Metropolitan Area (MCMA) and its evolution as it is uplifted and transported out of the MCMA basin was studied during the 2006 MILAGRO/MIRAGE-Mex field campaign. The results show that in the morning hours in the city center, the VOC distribution is dominated by non-methane hydrocarbons (NMHCs) but with a substantial contribution from oxygenated volatile organic compounds (OVOCs), predominantly from primary emissions. Alkanes account for a large part of the NMHC distribution in terms of mixing ratios. In terms of reactivity, NMHCs also dominate overall, especially in the morning hours. However, in the afternoon, as the boundary layer lifts and air is mixed and aged within the basin, the distribution changes as secondary products are formed. The WRF-Chem (Weather Research and Forecasting with Chemistry) model and MOZART (Model for Ozone and Related chemical Tracers) were able to reproduce the general features of the daytime cycle of the VOC OH reactivity distribution showing that NMHCs dominate the distribution except in the afternoon hours and that the VOC OH reactivity peaks in the early morning due to high morning emissions from the city into a shallow boundary layer. The WRF-Chem and MOZART models showed higher reactivity than the experimental data during the nighttime cycle, perhaps indicating problems with the modeled nighttime boundary layer height. In addition, a plume was studied in which air was advected out of the MCMA and intercepted downwind with the DOE G1 on 18 March and the NCAR C130 one day later on 19 March. A number of identical species measured aboard each aircraft gave insight into the chemical evolution of the plume as it aged and was transported as far as 1000 km downwind. Ozone and many OVOCs were photochemically produced in the plume. The WRF-Chem and MOZART models were used to examine the spatial and temporal extent of the 19 March plume and to help interpret the OH reactivity in the downwind plume. The model results generally showed good agreement with experimental results for the total VOC OH reactivity downwind and gave insight into the distributions of VOC chemical classes downwind. A box model with detailed gas phase chemistry (NCAR Master Mechanism), initialized with concentrations observed at one of the ground sites in the MCMA, was used to examine the expected evolution of specific VOCs over a 1-2 day period. The models clearly supported the experimental evidence for NMHC oxidation leading to the formation of OVOCs downwind, which then become the primary fuel for ozone production far away from the MCMA.

  10. The Residential Segregation of Same-Sex Partnered Households from Heterosexual Partnered Households: Metropolitan Statistical Areas in the U.S., 2010 

    E-Print Network [OSTI]

    Deng, Xiaodan

    2015-05-12

    to date. Figure 1, reproduced from Duncan and Duncan (1955), shows a geometrical def- inition of D as the maximum vertical dis- tance between the "segregation curve" and the curve Y = X. The segregation curve is the plot of the cumulative proportion... of whites versus the cumulative proportion of nonwhites, where the respective cumula- tions are obtained by taking the census tracts in order of increasing nonwhite per- centages. The Duncans provided a set of inade- quacies and precautionary comments...

  11. STAT 639V: Topics in Statistics Statistical Computing

    E-Print Network [OSTI]

    Petris, Giovanni

    methods. Most of the topics will be presented in the context of the R statistical computing language (see below). Computing: The computer language we will be using is R. The latest version of R is installedSTAT 639V: Topics in Statistics Fall 2014 Statistical Computing General Information: Class hours

  12. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Statistics Colloquium ANDREA MONTANARI Departments of Electrical Engineering and Statistics Stanford University Sharp Thresholds in Statistical an important role in some sta- tistical learning and statistical signal processing problems, in part because

  13. International petroleum statistics report

    SciTech Connect (OSTI)

    1995-10-01

    The International Petroleum Statistics Report is a monthly publication that provides current international oil data. This report presents data on international oil production, demand, imports, exports and stocks. The report has four sections. Section 1 contains time series data on world oil production, and on oil demand and stocks in the Organization for Economic Cooperation and Development (OECD). Section 2 presents an oil supply/demand balance for the world, in quarterly intervals for the most recent two years. Section 3 presents data on oil imports by OECD countries. Section 4 presents annual time series data on world oil production and oil stocks, demand, and trade in OECD countries.

  14. ARM - Historical Operational Statistics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Comments? WeDatastreamstps DocumentationAtlanticENAField ParticipantsField Campaign Statistics 2015

  15. ARM - Historical Visitor Statistics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Comments? WeDatastreamstps DocumentationAtlanticENAField ParticipantsField Campaign Statistics 2015Visitor

  16. Urban growth pattern and sustainable development: a comparative study of municipalities in the Seoul Metropolitan Region 

    E-Print Network [OSTI]

    Paek, Seunggeun

    2006-10-30

    sustainability in 31 study areas for the years 1990, 1995 and 2000. Data for this study were drawn from the 1990-2000 censuses and local government publications. Statistical methods such as t-test, analysis of variance and factor analysis were used to answer...

  17. Presented by Statistics at Scale

    E-Print Network [OSTI]

    .S. Department of Energy Contact George Ostrouchov Statistics and Data Sciences Computer Science and MathematicsPresented by Statistics at Scale George Ostrouchov Statistics and Data Sciences Computer Science and Mathematics Division #12;2 Managed by UT-Battelle for the U.S. Department of Energy Ostrouchov_SDS_SC10 Common

  18. PROGRAMME SPECIFICATION Programme title: Statistics

    E-Print Network [OSTI]

    Guillas, Serge

    in statistical theory and applications which enables graduates to enter specialist employment or academic in statistical computing and communication are assessed by coursework only. The summer project is assessedPROGRAMME SPECIFICATION Programme title: Statistics Final award (BSc, MA etc): (where stopping off

  19. Bulletin of the Seismological Society of America, Vol. 94, No. 6, pp. 21372163, December 2004 A Probabilistic Approach to Seismic Hazard in Metropolitan France

    E-Print Network [OSTI]

    Avouac, Jean-Philippe

    methods to seismic hazard assessment in France. This study differs from previous studies that have adopted A Probabilistic Approach to Seismic Hazard in Metropolitan France by Sylvie Marin, Jean-Philippe Avouac,* Marc Nicolas, and Antoine Schlupp Abstract In this study, we applied a probabilistic methodology to seismic

  20. Effects of urban land cover modifications in a mesoscale meteorological model on surface temperature and heat fluxes in the Phoenix metropolitan area.

    E-Print Network [OSTI]

    Hall, Sharon J.

    Effects of urban land cover modifications in a mesoscale meteorological model on surface between the two simulations. Mesoscale atmospheric models such as the Pennsylvania State University for the Phoenix metropolitan area was implemented in the fifth- generation PSU/NCAR mesoscale meteorological model

  1. Mathematical Modeling of Hepatitis C Prevalence Reduction with Antiviral Treatment Scale-Up in Persons Who Inject Drugs in Metropolitan Chicago

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Echevarria, Desarae; Gutfraind, Alexander; Boodram, Basmattee; Major, Marian; Del Valle, Sara; Cotler, Scott J.; Dahari, Harel

    2015-08-21

    New direct-acting antivirals (DAAs) provide an opportunity to combat hepatitis C virus (HCV) infection in persons who inject drugs (PWID). Here we use a mathematical model to predict the impact of a DAA-treatment scale-up on HCV prevalence among PWID and the estimated cost in metropolitan Chicago.

  2. East Coast Cool-Weather Storms in the New York Metropolitan Region Hunter College of the City University of New York, New York, New York

    E-Print Network [OSTI]

    Salmun, Haydee

    East Coast Cool-Weather Storms in the New York Metropolitan Region H. SALMUN Hunter College of the City University of New York, New York, New York A. MOLOD University of Maryland, Baltimore County of New York, New York, New York (Manuscript received 20 January 2009, in final form 3 May 2009) ABSTRACT

  3. Thermal Reactions of Uranium Metal, UO2, U3O8, UF4, and UO2F2 with NF3 to Produce UF6

    SciTech Connect (OSTI)

    McNamara, Bruce K.; Scheele, Randall D.; Kozelisky, Anne E.; Edwards, Matthew K.

    2009-11-01

    he objective of this paper is to demonstrate that NF3 fluorinates uranium metal, UO2, UF4, UO3, U3O8, and UO2F2•2H2O to produce the volatile UF6 at temperatures between 100 and 500?C. Thermogravimetric reaction profiles are described that reflect changes in the uranium oxidation state and discrete chemical speciation. Differences in the onset temperatures for each system indicate that NF3-substrate interactions are important for the temperature at which NF3 reacts: U metal > UO3 > UO2 > UO2F2 > UF4 and in fact may indicate different fluorination mechanisms for these various substrates. These studies demonstrate that NF3 is a potential replacement fluorinating agent in the existing nuclear fuel cycle and in oft-proposed actinide volatility reprocessing.

  4. International petroleum statistics report

    SciTech Connect (OSTI)

    1997-05-01

    The International Petroleum Statistics Report is a monthly publication that provides current international oil data. This report is published for the use of Members of Congress, Federal agencies, State agencies, industry, and the general public. Publication of this report is in keeping with responsibilities given the Energy Information Administration in Public Law 95-91. The International Petroleum Statistics Report presents data on international oil production, demand, imports, and stocks. The report has four sections. Section 1 contains time series data on world oil production, and on oil demand and stocks in the Organization for Economic Cooperation and Development (OECD). This section contains annual data beginning in 1985, and monthly data for the most recent two years. Section 2 presents an oil supply/demand balance for the world. This balance is presented in quarterly intervals for the most recent two years. Section 3 presents data on oil imports by OECD countries. This section contains annual data for the most recent year, quarterly data for the most recent two quarters, and monthly data for the most recent twelve months. Section 4 presents annual time series data on world oil production and oil stocks, demand, and trade in OECD countries. World oil production and OECD demand data are for the years 1970 through 1995; OECD stocks from 1973 through 1995; and OECD trade from 1985 through 1995.

  5. TCR and CD28 activate the transcription factor NF- B in T-cells viadistinct adaptor signaling complexes

    E-Print Network [OSTI]

    Thaker, Youg Raj; Schneider, Helga; Rudd, Christopher E.

    2014-10-23

    Article history: Received 19 A Received in re Accepted 15 O Available onlin Keywords: Adaptors ADAP VAV-1 GRB-2 NF-?B ed fo nd CD ng T- n wit ?B in F-?B p?/? m Over-expression of ADAP or its binding partner SKAP1 failed to enhance anti-CD28... to CD28 addition, Tu can deliver complexes co-operate Rac-1 and m Despite ponents of T-cells have various kno 170F) mice that the TC the NF-?B p that the CD ent signalin 2. Materia 2.1. Mice an DO11.10 (kindly pro School of M Dr. Erik Pe housed und...

  6. Nmero Nome 1T 2T R1T R2T E AC NF 42200 Armando Dias

    E-Print Network [OSTI]

    Baia, Margarida

    Sheet1 Page 1 Número Nome 1T 2T R1T R2T E AC NF 42200 Armando Dias 53515 Jorge Branco 55774 João 70100 Catarina Ferreira 70146 Mariana Castro 70364 Nuno Gaspar 70524 António Grego 10 2 5 70934 João.2 2 15 78167 Afonso Sarmento 13.8 8.3 7.6 2 12 78175 Carlos Martins 14.3 12.6 11 2 14 78183 Ana

  7. BS in STATISTICS: Statistical Science Emphasis (695220) MAP Sheet Department of Statistics

    E-Print Network [OSTI]

    Seamons, Kent E.

    the statistics list: C S 142 Introduction to Computer Programming Math 334 Ordinary Differential Equations Math Applied Time Series and Forecasting Stat 474 Theory of Interest Stat 496R Academic Internship: Statistics Stat 497R Introduction to Statistical Research Stat 535 Applied Linear Models Stat 536 Modern

  8. Fractons and Fractal Statistics

    E-Print Network [OSTI]

    Wellington da Cruz

    2000-07-31

    Fractons are anyons classified into equivalence classes and they obey a specific fractal statistics. The equivalence classes are labeled by a fractal parameter or Hausdorff dimension $h$. We consider this approach in the context of the Fractional Quantum Hall Effect (FQHE) and the concept of duality between such classes, defined by $\\tilde{h}=3-h$ shows us that the filling factors for which the FQHE were observed just appear into these classes. A connection between equivalence classes $h$ and the modular group for the quantum phase transitions of the FQHE is also obtained. A $\\beta-$function is defined for a complex conductivity which embodies the classes $h$. The thermodynamics is also considered for a gas of fractons $(h,\

  9. Comparison of Daytime and Nighttime Populations Adjacent to Interstate Highways in Metropolitan Areas Using LandScan USA

    SciTech Connect (OSTI)

    Johnson, Paul E [ORNL] [ORNL

    2007-01-01

    An article of similar title was published in the International Journal of Radioactive Materials Transport in 1999. The study concluded that the daytime and nighttime populations are not substantially different for the metropolitan areas examined. This study revisits the issue, but using the LandScan USA high resolution population distribution data, which includes daytime and night-time population. Segments of Interstate highway beltways, along with the direct route through the city, for Atlanta, St. Louis, and Kansas City are examined with an 800m buffer from either side of the highways. The day/night ratio of population is higher using the LandScan USA data. LandScan USA daytime and night-time data will be incorporated into the TRAGIS routing model in future.

  10. Statistics Online Computational Resource for Education

    E-Print Network [OSTI]

    Dinov, Ivo D; Christou, Nicolas

    2009-01-01

    and assess- ment of the statistic online computationalintroductory probability and statistics courses. Computers &Leslie, M. (2003). Statistics starter kit. Science, © 2009

  11. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Mohsen Pourahmadi Division of Statistics, Northern Illinois University and the Department of Statistics, The University of Chicago "Generalized

  12. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Statistics Colloquium Series JONATHAN WEARE sampling methods. The talk will have a computational statistical mechanics flavor but the methods

  13. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series JON MCAULIFFE Department of Statistics University of California, Berkeley "Statistical Methods for Genome Comparison" WEDNESDAY February

  14. International petroleum statistics report

    SciTech Connect (OSTI)

    1997-07-01

    The International Petroleum Statistics Report is a monthly publication that provides current international data. The report presents data on international oil production, demand, imports, and stocks. The report has four sections. Section 1 contains time series data on world oil production, and on oil demand and stocks in the Organization for Economic Cooperation and Development (OECD). This section contains annual data beginning in 1985, and monthly data for the most recent two years. Section 2 presents an oil supply/demand balance for the world. This balance is presented in quarterly intervals for the most recent two years. Section 3 presents data on oil imports by OECD countries. This section contains annual data for the most recent year, quarterly data for the most recent two quarters, and monthly data for the most recent 12 months. Section 4 presents annual time series data on world oil production and oil stocks, demand, and trade in OECD countries. World oil production and OECD demand data are for the years 1970 through 1996; OECD stocks from 1973 through 1996; and OECD trade from 1986 through 1996.

  15. International petroleum statistics report

    SciTech Connect (OSTI)

    1995-07-27

    The International Petroleum Statistics Report presents data on international oil production, demand, imports, and exports, and stocks. The report has four sections. Section 1 contains time series data on world oil production, and on oil demand and stocks in the Organization for Economic Cooperation and Development (OECD). This section contains annual data beginning in 1985, and monthly data for the most recent two years. Section 2 presents an oil supply/demand balance for the world. This balance is presented in quarterly intervals for the most recent two years. Section 3 presents data on oil imports by OECD countries. This section contains annual data for the most recent year, quarterly data for the most recent two quarters, and monthly data for the most recent twelve months. Section 4 presents annual time series data on world oil production and oil stocks, demand, and trade in OECD countries. World oil production and OECD demand data are for the years 1970 through 1994; OECD stocks from 1973 through 1994; and OECD trade from 1984 through 1994.

  16. International petroleum statistics report

    SciTech Connect (OSTI)

    1995-11-01

    The International Petroleum Statistics Report presents data on international oil production, demand, imports, exports, and stocks. The report has four sections. Section 1 contains time series data on world oil production, and on oil demand and stocks in the Organization for Economic Cooperation and Development (OECD). This section contains annual data beginning in 1985, and monthly data for the most recent two years. Section 2 presents an oil supply/demand balance for the world. This balance is presented in quarterly intervals for the most recent two years. Section 3 presents data on oil imports by OECD countries. This section contains annual data for the most recent year, quarterly data for the most recent two quarters, and monthly data for the most recent twelve months. Section 4 presents annual time series data on world oil production and oil stocks, demand, and trade in OECD countries. World oil production and OECD demand data are for the years 1970 through 1994; OECD stocks from 1973 through 1994; and OECD trade from 1984 through 1994.

  17. International petroleum statistics report

    SciTech Connect (OSTI)

    1996-10-01

    The International Petroleum Statistics Report presents data on international oil production, demand, imports, and stocks. The report has four sections. Section 1 contains time series data on world oil production, and on oil demand and stocks in the Organization for Economic Cooperation and Development (OECD). This section contains annual data beginning in 1985, and monthly data for the most recent two years. Section 2 presents an oil supply/demand balance for the world. This balance is presented in quarterly intervals for the most recent two years. Section 3 presents data on oil imports by OECD countries. This section contains annual data for the most recent year, quarterly data for the most recent two quarters, and monthly data for the most recent twelve months. Section 4 presents annual time series data on world oil production and oil stocks, demand, and trade in OECD countries. Word oil production and OECD demand data are for the years 1970 through 1995; OECD stocks from 1973 through 1995; and OECD trade from 1985 through 1995.

  18. International petroleum statistics report

    SciTech Connect (OSTI)

    1996-05-01

    The International Petroleum Statistics Report presents data on international oil production, demand, imports, exports, and stocks. The report has four sections. Section 1 contains time series data on world oil production, and on oil demand and stocks in the Organization for Economic Cooperation and Development (OECD). This section contains annual data beginning in 1985, and monthly data for the most recent two years. Section 2 presents an oil supply/demand balance for the world. This balance is presented in quarterly intervals for the most recent two years. Section 3 presents data on oil imports by OECD countries. This section contains annual data for the most recent year, quarterly data for the most recent two quarters, and monthly data for the most recent twelve months. Section 4 presents annual time series data on world oil production and oil stocks, demand, and trade in OECD countries. World oil production and OECD demand data are for the years 1970 through 1995; OECD stocks from 1973 through 1995; and OECD trade from 1084 through 1994.

  19. Statistics as a dynamical attractor

    E-Print Network [OSTI]

    Michail Zak

    2012-08-30

    It is demonstrated that any statistics can be represented by an attractor of the solution to a corresponding systen of ODE coupled with its Liouville equation. Such a non-Newtonian representation allows one to reduce foundations of statistics to better established foundations of ODE. In addition to that, evolution to the attractor reveals possible micro-mechanisms driving random events to the final distribution of the corresponding statistical law. Special attention is concentrated upon the power law and its dynamical interpretation: it is demonstrated that the underlying dynamics supports a " violent reputation" of the power law statistics.

  20. Statistical mechanics of the cytoskeleton

    E-Print Network [OSTI]

    Wang, Shenshen

    2012-01-01

    mechanics . . . . . . . . . . . . . . . . . . . . . . 2.1bottom-up approach to cell mechanics. Nat. Phys. [6] Fabry,Wolynes, P. G. Statistical mechanics of a cat’s cradle. New

  1. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Statistics Colloquium ALEKH AGARWAL Electrical Engineering and Computer Science University of California Berkeley Computation Meet Statistics: Trade that provide complementary lines of attack on this broader research agenda: (i) lower bounds for statistical

  2. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series TONG ZHANG Department of Statistics Rutgers University High Dimensional Statistical Analysis for Complex Sparse Estimation Problems the seminar in Eckhart 110. ABSTRACT This talk presents theoretical results for high dimensional statistical

  3. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series PETER HALL Department of Mathematics and Statistics University of Melbourne, Australia Contemporary Frontiers in Statistics THURSDAY and future directions of frontier problems in statistics For further information and about building access

  4. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics SUMMER Seminar Series ANDREW GELMAN Departments of Statistics and Political Science Columbia University Parameterization and Bayesian Modeling THURSDAY and location. ABSTRACT Progress in statistical computation often leads to advances in statistical modeling

  5. Department: Statistics Course No: STAT 261Q

    E-Print Network [OSTI]

    Alpay, S. Pamir

    Department: Statistics Course No: STAT 261Q Title: Statistical Computing Credits: 3 Contact : Dipak. Recommended preparation: An applied statistics course. Open only with consent of instructor. Introduction to computing for statistical problems; obtaining features of distributions, fitting models and implementing

  6. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Statistics Colloquium Series MONTSERRAT FUENTES Department of Statistics North Carolina State University Nonparametric Spatial Models for Extremes events at different locations. Although the tools for statistical modeling of univariate extremes

  7. APS Operational Statistics for FY 2015

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    5 Operational Statistics Back to Main Statistics Page FY 2015 Year-to-Date Statistics 2015 Statistics Summary HTML or PDF FY 2015 Reliability Summary HTML or PDF FY 2015 Bar Chart...

  8. Etching of UO{sub 2} in NF{sub 3} RF Plasma Glow Discharge

    SciTech Connect (OSTI)

    John M. Veilleux

    1999-08-01

    A series of room temperature, low pressure (10.8 to 40 Pa), low power (25 to 210 W) RF plasma glow discharge experiments with UO{sub 2} were conducted to demonstrate that plasma treatment is a viable method for decontaminating UO{sub 2} from stainless steel substrates. Experiments were conducted using NF{sub 3} gas to decontaminate depleted uranium dioxide from stainless-steel substrates. Depleted UO{sub 2} samples each containing 129.4 Bq were prepared from 100 microliter solutions of uranyl nitrate hexahydrate solution. The amorphous UO{sub 2} in the samples had a relatively low density of 4.8 gm/cm{sub 3}. Counting of the depleted UO{sub 2} on the substrate following plasma immersion was performed using liquid scintillation counting with alpha/beta discrimination due to the presence of confounding beta emitting daughter products, {sup 234}Th and {sup 234}Pa. The alpha emission peak from each sample was integrated using a gaussian and first order polynomial fit to improve quantification. The uncertainties in the experimental measurement of the etched material were estimated at about {+-} 2%. Results demonstrated that UO{sub 2} can be completely removed from stainless-steel substrates after several minutes processing at under 200 W. At 180 W and 32.7 Pa gas pressure, over 99% of all UO{sub 2} in the samples was removed in just 17 minutes. The initial etch rate in the experiments ranged from 0.2 to 7.4 {micro}m/min. Etching increased with the plasma absorbed power and feed gas pressure in the range of 10.8 to 40 Pa. A different pressure effect on UO{sub 2} etching was also noted below 50 W in which etching increased up to a maximum pressure, {approximately}23 Pa, then decreased with further increases in pressure.

  9. Models for Millions Department of Statistics

    E-Print Network [OSTI]

    Stine, Robert A.

    Models for Millions Bob Stine Department of Statistics The Wharton School, UniversityDepartment of Statistics Introduction #12;WhartonDepartment of Statistics WhartonDepartment of Statistics Statistics in the News Hot topics Big Data Business Analytics Data Science Are the authors talking about statistics

  10. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Hira L. Koul Department of Statistics). Statistical methods for data with long-range dependence. (With discussion). Statist. Sci. 7, 404-427. Beran, J. (1994). Statistics for Long-Memory Processes. Monographs on Statistics and Applied Probab., 61. Chapman

  11. MATHEMATICS & STATISTICS Program of Study

    E-Print Network [OSTI]

    Thomas, Andrew

    MATHEMATICS & STATISTICS Program of Study Degree Requirements The Department offers a program leading to the degree of Master of Arts in Mathematics. The program outlined below offers the student three "pathways" or tracks for advanced study in mathematics: pure, interdisciplinary, and statistics

  12. Statistical Theory Prof. Gesine Reinert

    E-Print Network [OSTI]

    Reinert, Gesine

    - chical Bayes, empirical Bayes, James-Stein estimators, Bayesian computation. · Part 4: Principles) Statistical Inference. Second Edi- tion. Thomson Learning. 3. Cox, D.R. and Hinkley, D.V. (1974) Theoretical. Cambridge University Press. 2 #12;6. Lindgren, B.W. (1993) Statistical Theory. 4th edition. Chapman and Hall

  13. December 2000 A STATISTICAL TEST

    E-Print Network [OSTI]

    December 2000 A STATISTICAL TEST SUITE FOR RANDOM AND PSEUDORANDOM NUMBER GENERATORS challenges in authentication protocols. NIST Special Publication (SP) 800-22, A Statistical Test Suite testing of random number and pseudorandom number generators (RNGs and PRNGs) that may be used for many

  14. Practical Statistics for the LHC

    E-Print Network [OSTI]

    Kyle Cranmer

    2015-03-26

    This document is a pedagogical introduction to statistics for particle physics. Emphasis is placed on the terminology, concepts, and methods being used at the Large Hadron Collider. The document addresses both the statistical tests applied to a model of the data and the modeling itself.

  15. A (P)HMC algorithm for N_f = 2 + 1 + 1 flavours of twisted mass fermions

    E-Print Network [OSTI]

    T. Chiarappa; R. Frezzotti; C. Urbach

    2005-09-27

    We present a detailed design of a (P)HMC simulation algorithm for N_f = 2 + 1 + 1 maximally twisted Wilson quark flavours. The algorithm retains even/odd and mass-shift preconditionings combined with multiple Molecular Dynamics time scales for both the light mass degenerate, u and d, quarks and the heavy mass non-degenerate, s and c, quarks. Various non-standard aspects of the algorithm are discussed, among which those connected to the use of a polynomial approximation for the inverse (square root of the squared) Dirac matrix in the s and c quark sector.

  16. Determination of c_sw in N_f=3+1 Lattice QCD with massive Wilson fermions

    E-Print Network [OSTI]

    Patrick Fritzsch; Rainer Sommer; Felix Stollenwerk; Ulli Wolff

    2015-01-27

    We develop a strategy for the non-perturbative determination of the O(a)-improvement coefficient c_sw for Wilson fermions with massive sea quarks. The improvement condition is defined via the PCAC relation in the Schr\\"odinger functional. It is imposed along a line of constant physics designed to be close to the correct mass of the charm quark. The numerical work uses the tree-level improved L\\"uscher-Weisz gauge action in N_f=3+1 Lattice QCD.

  17. SHARE: Statistical Hadronization with Resonances

    E-Print Network [OSTI]

    Giorgio Torrieri; Steve Steinke; Wojciech Broniowski; Wojciech Florkowski; Jean Letessier; Johann Rafelski

    2004-07-22

    SHARE is a collection of programs designed for the statistical analysis of particle production in relativistic heavy-ion collisions. With the physical input of intensive statistical parameters, it generates the ratios of particle abundances. The program includes cascade decays of all confirmed resonances from the Particle Data Tables. The complete treatment of these resonances has been known to be a crucial factor behind the success of the statistical approach. An optional feature implemented is a Breit--Wigner type distribution for strong resonances. An interface for fitting the parameters of the model to the experimental data is provided.

  18. Key China Energy Statistics 2012

    SciTech Connect (OSTI)

    Levine, Mark; Fridley, David; Lu, Hongyou; Fino-Chen, Cecilia

    2012-05-01

    The China Energy Group at Lawrence Berkeley National Laboratory (LBNL) was established in 1988. Over the years the Group has gained recognition as an authoritative source of China energy statistics through the publication of its China Energy Databook (CED). The Group has published seven editions to date of the CED (http://china.lbl.gov/research/chinaenergy-databook). This handbook summarizes key statistics from the CED and is expressly modeled on the International Energy Agency’s “Key World Energy Statistics” series of publications. The handbook contains timely, clearly-presented data on the supply, transformation, and consumption of all major energy sources.

  19. Key China Energy Statistics 2011

    SciTech Connect (OSTI)

    Levine, Mark; Fridley, David; Lu, Hongyou; Fino-Chen, Cecilia

    2012-01-15

    The China Energy Group at Lawrence Berkeley National Laboratory (LBNL) was established in 1988. Over the years the Group has gained recognition as an authoritative source of China energy statistics through the publication of its China Energy Databook (CED). In 2008 the Group published the Seventh Edition of the CED (http://china.lbl.gov/research/chinaenergy-databook). This handbook summarizes key statistics from the CED and is expressly modeled on the International Energy Agency’s “Key World Energy Statistics” series of publications. The handbook contains timely, clearly-presented data on the supply, transformation, and consumption of all major energy sources.

  20. Quantum particles from classical statistics

    E-Print Network [OSTI]

    C. Wetterich

    2010-02-11

    Quantum particles and classical particles are described in a common setting of classical statistical physics. The property of a particle being "classical" or "quantum" ceases to be a basic conceptual difference. The dynamics differs, however, between quantum and classical particles. We describe position, motion and correlations of a quantum particle in terms of observables in a classical statistical ensemble. On the other side, we also construct explicitly the quantum formalism with wave function and Hamiltonian for classical particles. For a suitable time evolution of the classical probabilities and a suitable choice of observables all features of a quantum particle in a potential can be derived from classical statistics, including interference and tunneling. Besides conceptual advances, the treatment of classical and quantum particles in a common formalism could lead to interesting cross-fertilization between classical statistics and quantum physics.

  1. STATISTICAL MECHANICS AND FIELD THEORY

    E-Print Network [OSTI]

    Samuel, S.A.

    2010-01-01

    1. L. 1. Schiff, Quantum Mechanics, third edition (McGraw-two-dimensional quantum mechanics problem vith a potential,Theory Methods to Statistical Mechanics Chapter I The Use of

  2. Using excel to do statistics

    E-Print Network [OSTI]

    Dave

    2012-03-25

    Statistics in Excel. 1. Type the measurement data into consecutive cells in Excel. NOTE: they do not need to be in one column, but the cells should be adjacent.

  3. Intermediate wave-function statistics

    E-Print Network [OSTI]

    G. Berkolaiko; J. P. Keating; B. Winn

    2003-08-05

    We calculate statistical properties of the eigenfunctions of two quantum systems that exhibit intermediate spectral statistics: star graphs and Seba billiards. First, we show that these eigenfunctions are not quantum ergodic, and calculate the corresponding limit distribution. Second, we find that they can be strongly scarred by short periodic orbits, and construct sequences of states which have such a limit. Our results are illustrated by numerical computations.

  4. Anyonic statistics with continuous variables

    E-Print Network [OSTI]

    Jing Zhang; Changde Xie; Kunchi Peng; Peter van Loock

    2008-10-30

    We describe a continuous-variable scheme for simulating the Kitaev lattice model and for detecting statistics of abelian anyons. The corresponding quantum optical implementation is solely based upon Gaussian resource states and Gaussian operations, hence allowing for a highly efficient creation, manipulation, and detection of anyons. This approach extends our understanding of the control and application of anyons and it leads to the possibility for experimental proof-of-principle demonstrations of anyonic statistics using continuous-variable systems.

  5. Angiotensin II modulates interleukin-1{beta}-induced inflammatory gene expression in vascular smooth muscle cells via interfering with ERK-NF-{kappa}B crosstalk

    SciTech Connect (OSTI)

    Xu, Shanqin [Vascular Biology Unit, Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA (United States)] [Vascular Biology Unit, Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA (United States); Zhi, Hui [Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (United States)] [Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (United States); Hou, Xiuyun [Vascular Biology Unit, Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA (United States)] [Vascular Biology Unit, Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA (United States); Jiang, Bingbing, E-mail: bjiang1@rics.bwh.harvard.edu [Vascular Biology Unit, Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA (United States) [Vascular Biology Unit, Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA (United States); Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (United States)

    2011-07-08

    Highlights: {yields} We examine how angiotensin II modulates ERK-NF-{kappa}B crosstalk and gene expression. {yields} Angiotensin II suppresses IL-1{beta}-induced prolonged ERK and NF-{kappa}B activation. {yields} ERK-RSK1 signaling is required for IL-1{beta}-induced prolonged NF-{kappa}B activation. {yields} Angiotensin II modulates NF-{kappa}B responsive genes via regulating ERK-NF-{kappa}B crosstalk. {yields} ERK-NF-{kappa}B crosstalk is a novel mechanism regulating inflammatory gene expression. -- Abstract: Angiotensin II is implicated in cardiovascular diseases, which is associated with a role in increasing vascular inflammation. The present study investigated how angiotensin II modulates vascular inflammatory signaling and expression of inducible nitric oxide synthase (iNOS) and vascular cell adhesion molecule (VCAM)-1. In cultured rat aortic vascular smooth muscle cells (VSMCs), angiotensin II suppressed interleukin-1{beta}-induced prolonged phosphorylation of extracellular signal-regulated kinase (ERK) and ribosomal S6 kinase (RSK)-1, and nuclear translocation of nuclear factor (NF)-{kappa}B, leading to decreased iNOS but enhanced VCAM-1 expression, associated with an up-regulation of mitogen-activated protein kinase phosphatase-1 expression. Knock-down of RSK1 selectively down regulated interleukin-1{beta}-induced iNOS expression without influencing VCAM-1 expression. In vivo experiments showed that interleukin-1{beta}, iNOS, and VCAM-1 expression were detectable in the aortic arches of both wild-type and apolipoprotein E-deficient (ApoE{sup -/-}) mice. VCAM-1 and iNOS expression were higher in ApoE{sup -/-} than in wild type mouse aortic arches. Angiotensin II infusion (3.2 mg/kg/day, for 6 days, via subcutaneous osmotic pump) in ApoE{sup -/-} mice enhanced endothelial and adventitial VCAM-1 and iNOS expression, but reduced medial smooth muscle iNOS expression associated with reduced phosphorylation of ERK and RSK-1. These results indicate that angiotensin II can differentially modulate inflammatory gene expression in aortic smooth muscle cells through influencing ERK-NF-{kappa}B crosstalk, which may contribute to angiotensin II-induced inflammatory disorders related to cardiovascular diseases.

  6. FISHERY STATISTICS QF THE UNITED STATES

    E-Print Network [OSTI]

    I FISHERY STATISTICS QF THE UNITED STATES 1942 By A. W, ANDERSON and E. A. POWER STATISTICAL DIGEST Statistical Digest No. 11 FISHERY STATISTICS OF THE UNITED STATES 1942 BY A. W. ANDERSON and E. A. POWER. S. Government Printing Offic Washington 25, D. C. - Price 60 cents #12;Fishery Statistics

  7. UNIVERSITY OF OXFORD DEPARTMENT OF STATISTICS

    E-Print Network [OSTI]

    Oxford, University of

    UNIVERSITY OF OXFORD DEPARTMENT OF STATISTICS MSc AND DIPLOMA IN APPLIED STATISTICS 2014. Sources of advice and help 33 5. Departmental Facilities 35 #12;2 MSc/ DIPLOMA IN APPLIED STATISTICS 2014/2015 We welcome you to the Department of Statistics and our MSc programme in Applied Statistics

  8. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES 1962 STATISTICAL DIGEST NO. 56 UNITED STATES DEPARTMENT Fisheries, Donald L. McKernan, Director STATISTICAL DIGEST 56 FISHERY STATISTICS OF THE UNITED STATES 1962.S. Government Printing Office, Washington, D.C., 20402 - Price $2.25 (paper cover) #12;Fishery statistics

  9. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    pa%Mv--. FISHERY STATISTICS OF THE UNITED STATES 1965 STATISTICAL DIGEST NO. 59 UNITED STATES, Commissioner Bureau of Commercial Fisheries, H. E. Crowther, Director STATISTICAL DIGEST 59 FISHERY STATISTICS.S. Government Printing Office Washington, D.C. 20402 - Price $4 (Paper Cover) #12;Fishery statistics

  10. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES 1950 STATISTICAL DIGEST NO. 27 Fish and Wildlife ServiceKay, Secretary FISH AND WILDLIFE SERVICE, John L. Farley, Director Statistical Digest 27 FISHERY STATISTICS 25, DC. - - Price $2.00 (paper) #12;Fishery Statistics of the United States and A] aska are corapi

  11. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES 1964 STATISTICAL DIGEST NO. 58 UNITED STATES DEPARTMENT Bureau of Commercial Fisheries, Donald L. McKernan, Director STATISTICAL DIGEST 58 FISHERY STATISTICS.S. Government Printing Office, Washington, D.C., 20402 - Price S2.50 (paper cover) #12;Fishery statistics

  12. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    Div,, . FISHERY STATISTICS OF THE UNITED STATES 1961 STATISTICAL DIGEST NO. 54 UNITED STATES, Donald L. MeKernan, Director STATISTICAL DIGEST 54 FISHERY STATISTICS OF THE UNITED STATES 1961 BY E. A, Washington, D.C. 20402 - Price $2 (paper cover) #12;Fishery statistics of the United States are compiled

  13. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    SH 11 A443X FISH FISHERY STATISTICS OF THE UNITED STATES 1943 STATISTICAL DIGEST NO. 14 Sll \\M AND WILDLIFE SERVICE Albert M. Day, Director CAMEL M. COHEN Statistical Digest No. 14 FISHERY STATISTICS. - Price 75 cents #12;Fishery Statistics of the United States and Alaska are compiled and published

  14. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES 1944 STATISTICAL DIGEST ISO. 16 Fish and Wildlife Sekvh Albert M. Day, Director Statistical Digest No. 16 FISHERY STATISTICS OF THE UNITED STATES 1944 BY A. W Statistics of the United States and Alaska are coiip i I ed and published annually to make available

  15. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES 1963 STATISTICAL DIGEST NO. 57 UNITED STATES DEPARTMENT of Commercial Fisheries, Donald L. McKernan, Director STATISTICAL DIGEST 57 FISHERY STATISTICS OF THE UNITEDTernment Printing Office, Washington, D.C., 20402 - Price $2.25 (paper c #12;Fishery statistics of the United States

  16. FISHERY STATISTICS )F THE UNITED STATES

    E-Print Network [OSTI]

    SH 11 .A443X FISH FISHERY STATISTICS )F THE UNITED STATES ^M=^. STATISTICAL DIGEST NO. 36 #12. Farley, Director i]EL M. COHEN Statistical Digest 36 FISHERY STATISTICS OF THE UNITED STATES 1953 BY A. W;Fishery Statistics of the I'nited States and Alaska are compiled and published an- nually to make

  17. Accuracy and reliability of China's energy statistics

    E-Print Network [OSTI]

    Sinton, Jonathan E.

    2001-01-01

    the primary energy production and consumption statistics areProduction Hydroelectricity Primary Consumption J.E.Sinton, China’s Energy StatisticsStatistics Mtce Primary Consumption Coal Primary Consumption Total Energy Primary Production

  18. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Matthew Stephens Department of Statistics, University of Washington "Exploring Heterogeneity in Recombination Rates Across the Genome. In this talk I describe a statistical method that comes some way towards addressing these deficiencies

  19. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series JUN LIU Department of Statistics with classification problems. I will also discuss the issue of statistical significance in this situation Please send

  20. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Tiefeng JIANG School of Statistics). A history from 1914 to 2003 of the problem from Mechanics, Statistics and Imagine Analysis will also

  1. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series JIANQING FAN Department of Statistics Princeton University "Nonparametric specification tests for diffusion models in financial null distributions of proposed test statistics and compute their power func- tions. The finite sample

  2. APS Operational Statistics for FY 2009

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Back to Main Statistics Page FY 2009 Year-to-Date Statistics 2009 Statistics Summary HTML or PDF FY 2009 Reliability Summary HTML or PDF FY 2009 Bar Chart of Downtime by System...

  3. APS Operational Statistics for FY 2008

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Back to Main Statistics Page FY 2008 Year-to-Date Statistics 2008 Statistics Summary HTML or PDF FY 2008 Reliability Summary HTML or PDF FY 2008 Bar Chart of Downtime by System...

  4. APS Operational Statistics for FY 2014

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Back to Main Statistics Page FY 2014 Year-to-Date Statistics 2014 Statistics Summary HTML or PDF FY 2014 Reliability Summary HTML or PDF FY 2014 Bar Chart of Downtime by System...

  5. APS Operational Statistics for FY 2005

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Back to Main Statistics Page FY 2005 Year-to-Date Statistics 2005 Statistics Summary HTML or PDF FY 2005 Reliability Summary HTML or PDF FY 2005 Bar Chart of Downtime by System...

  6. APS Operational Statistics for FY 2007

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Back to Main Statistics Page FY 2007 Year-to-Date Statistics 2007 Statistics Summary HTML or PDF FY 2007 Reliability Summary HTML or PDF FY 2007 Bar Chart of Downtime by System...

  7. APS Operational Statistics for FY 2012

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Back to Main Statistics Page FY 2012 Year-to-Date Statistics 2012 Statistics Summary HTML or PDF FY 2012 Reliability Summary HTML or PDF FY 2012 Bar Chart of Downtime by System...

  8. APS Operational Statistics for FY 2006

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Back to Main Statistics Page FY 2006 Year-to-Date Statistics 2006 Statistics Summary HTML or PDF FY 2006 Reliability Summary HTML or PDF FY 2006 Bar Chart of Downtime by System...

  9. APS Operational Statistics for FY 2010

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Back to Main Statistics Page FY 2010 Year-to-Date Statistics 2010 Statistics Summary HTML or PDF FY 2010 Reliability Summary HTML or PDF FY 2010 Bar Chart of Downtime by System...

  10. APS Operational Statistics for FY 2013

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Back to Main Statistics Page FY 2013 Year-to-Date Statistics 2013 Statistics Summary HTML or PDF FY 2013 Reliability Summary HTML or PDF FY 2013 Bar Chart of Downtime by System...

  11. STATISTICAL PHONE: 530.752.2361

    E-Print Network [OSTI]

    Wang, Jane-Ling

    . from 1995 to 1998, he developed further expertise in software develop- ment, statistical programming, analysis, programming, and interpretation. Since joining the Statistical Laboratory in 2005, he has R. Beran: multivariate regression, bootstrap meth- ods, statistics on manifolds, asymptotic theory P

  12. 5.72 Statistical Mechanics, Spring 2008

    E-Print Network [OSTI]

    Cao, Jianshu

    This course discusses the principles and methods of statistical mechanics. Topics covered include classical and quantum statistics, grand ensembles, fluctuations, molecular distribution functions, other concepts in equilibrium ...

  13. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Michael Woodroofe Department of Statistics, University of Michigan "Inference with a Restricted Parameter Space

  14. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series ANDREW C. THOMAS Department of Statistics Harvard University Uncertainties in Network Analysis Due to the Thresholding Problem WEDNESDAY

  15. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series ARNAUD DOUCET Departments of Computer Science and Statistics University of British Columbia The Expected Auxiliary Variable Method

  16. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series DAG TJOSTHEIM Department of Statistics University of Bergen, Norway Gaussian Local Likelihood and Local Correlation MONDAY, April 28

  17. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series YUN S. SONG Departments of Electrical Engineering and Computer Sciences, and Statistics University of California, Berkeley A Universal

  18. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Anirban Dasgupta Department of Statistics Purdue University "Inference Based on Total Variation Distance" Monday, November 10, 2003 at 4

  19. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series HELENE MASSAM Department of Mathematics and Statistics York University, Toronto, Canada "Two New Families of Conjugate Priors

  20. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series YUGUO CHEN Department of Statistics University of Illinois at Urbana-Champaign "Sampling for Conditional Inference on Multiway Tables

  1. ORISE: Statistical Analyses of Worker Health

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    appropriate methods of statistical analysis to a variety of problems in occupational health and other areas. Our expertise spans a range of capabilities essential for statistical...

  2. Apolipoprotein E inhibits osteoclast differentiation via regulation of c-Fos, NFATc1 and NF-?B

    SciTech Connect (OSTI)

    Kim, Woo-Shin; Kim, Hyung Joon; Lee, Zang Hee [Department of Cell and Developmental Biology, BK21 Program and Dental Research Institute, Seoul National University, 28 Yeongon-Dong, Chongno-Gu, Seoul 110-749 (Korea, Republic of); Lee, Youngkyun [Department of Biochemistry, School of Dentistry, Kyungpook National University, Daegu 700-422 (Korea, Republic of); Kim, Hong-Hee, E-mail: hhbkim@snu.ac.kr [Department of Cell and Developmental Biology, BK21 Program and Dental Research Institute, Seoul National University, 28 Yeongon-Dong, Chongno-Gu, Seoul 110-749 (Korea, Republic of)

    2013-02-15

    Apolipoprotein E (ApoE) plays a major role in the transport and metabolism of lipid. Other functions of ApoE include modulation of innate and adaptive immune responses. The expression of ApoE in osteoblasts and its relevance with bone formation have also been reported. However, the effect of ApoE on osteoclasts has not yet been examined. Here, we investigated the role of ApoE in osteoclast differentiation using bone marrow-derived macrophages (BMMs) and RAW264.7 cells. We found a down-regulation of ApoE gene expression during osteoclastic differentiation of those cells. Overexpression of ApoE in BMMs and RAW264.7 cells significantly blocked the induction of c-Fos and nuclear factor of activated T cell c1 (NFATc1), transcription factors critical for expression of osteoclast marker genes, by receptor activator of nuclear factor ?B ligand (RANKL), the osteoclast differentiation factor. ApoE inhibited osteoclast differentiation, as measured by decreased number of tartrate-resistant acid phosphatase (TRAP)-positive multinuclear cells (MNCs). In addition, ApoE reduced the expression of dendritic cell-specific transmembrane protein (DC-STAMP) and ATPase, H{sup +} transporting, lysosomal 38 kDa, V0 subunit d2 (ATP6v0d2), genes involved in cell–cell fusion during osteoclastogenesis. Knock-down of ApoE using a specific siRNA promoted the RANKL-mediated induction of osteoclast differentiation. While ApoE did not affect the activation of ERK, JNK, and p38 MAPK signaling pathways by RANKL, the phosphorylation of p65 trans-activation domain on serine 536 and transcription activity of NF-?B were reduced by ApoE overexpression. These findings suggest that ApoE plays an inhibitory role in osteoclast differentiation via the suppression of RANKL-dependent activation of NF-?B and induction of c-Fos and NFATc1. - Highlights: ? Apolipoprotein E (ApoE) significantly inhibited osteoclast differentiation and activation of NF-?B. ? ApoE decreased the induction of osteoclast marker genes such as c-Fos, NFATc1, TRAP, DC-STAMP and Cathepsin K. ? ApoE reduced number of TRAP-positive multinuclear cells. ? Exogenous ApoE inhibits osteoclast formation by reduction of crucial factor of osteoclast differentiation. ? knock-down of ApoE promoted the RANKL-mediated induction of osteoclast differentiation.

  3. STATISTICS IN MEDICINE Statist. Med. 18, 32213234 (1999)

    E-Print Network [OSTI]

    Gelman, Andrew

    1999-01-01

    States. Much of the variation in observed cancer death rates by county is attributable to statistical to have extremely high (or low) cancer rates when compared to typical counties in the United States. Thus to keep a speciÿc example in mind. Consider the mapping of cancer mortality rates by county in the United

  4. STAT 639v: Topics in Statistics Statistical Computing

    E-Print Network [OSTI]

    Petris, Giovanni

    , or by appointment. Textbooks: Braun and Murdoch (2007), A First Course in Statistical Programming with R, Cambridge roughly every two or three weeks. Outline syllabus: After learning the R programming language, we, the bootstrap. Computing: The computer language we will be using is R. The latest version of R is installed

  5. Differential Effects of ?-catenin and NF-?B Interplay in the Regulation of Cell Proliferation, Inflammation and Tumorigenesis in Response to Bacterial Infection

    E-Print Network [OSTI]

    Chandrakesan, Parthasarathy; Jakkula, Laxmi Uma Maheswar Rao; Ahmed, Ishfaq; Roy, Badal; Anant, Shrikant; Umar, Shahid

    2013-11-21

    Both ?-catenin and NF-?B have been implicated in our laboratory as candidate factors in driving proliferation in an in vivo model of Citrobacter rodentium (CR)-induced colonic crypt hyper-proliferation and hyperplasia. Herein, we test the hypothesis...

  6. GRP94/gp96 Elicits ERK Activation in Murine Macrophages A ROLE FOR ENDOTOXIN CONTAMINATION IN NF-B ACTIVATION AND NITRIC OXIDE PRODUCTION*

    E-Print Network [OSTI]

    Nicchitta, Chris

    GRP94/gp96 Elicits ERK Activation in Murine Macrophages A ROLE FOR ENDOTOXIN CONTAMINATION IN NF- B signaling and ni- tric oxide production, as well as the MAP kinase p38, JNK, and ERK signaling cascades a marked increase in ERK phosphorylation at protein concentrations as low as 2 g/ml. These results

  7. Statistical Mechanics of Black Holes

    E-Print Network [OSTI]

    B. Harms; Y. Leblanc

    1992-05-11

    We analyze the statistical mechanics of a gas of neutral and charged black holes. The microcanonical ensemble is the only possible approach to this system, and the equilibrium configuration is the one for which most of the energy is carried by a single black hole. Schwarzschild black holes are found to obey the statistical bootstrap condition. In all cases, the microcanonical temperature is identical to the Hawking temperature of the most massive black hole in the gas. U(1) charges in general break the bootstrap property. The problems of black hole decay and of quantum coherence are also addressed.

  8. Osthole inhibits the invasive ability of human lung adenocarcinoma cells via suppression of NF-?B-mediated matrix metalloproteinase-9 expression

    SciTech Connect (OSTI)

    Kao, Shang-Jyh [Department of Chest Medicine, Shin-Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China) [Department of Chest Medicine, Shin-Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan (China); School of Respiratory Therapy, Taipei Medical University, Taipei Taiwan (China); Su, Jen-Liang [Graduate Institute of Cancer Biology, College of Medicine, China Medical University, Taichung, Taiwan (China) [Graduate Institute of Cancer Biology, College of Medicine, China Medical University, Taichung, Taiwan (China); Center for Molecular Medicine, China Medical University Hospital, Taichung, Taiwan (China); Department of Biotechnology, Asia University, Taichung, Taiwan (China); Chen, Chi-Kuan [Graduate Institute of Toxicology, College of Medicine, National Taiwan University, Taipei, Taiwan (China)] [Graduate Institute of Toxicology, College of Medicine, National Taiwan University, Taipei, Taiwan (China); Yu, Ming-Chih; Bai, Kuan-Jen; Chang, Jer-Hua [Division of Pulmonary Medicine, Department of Internal Medicine, Taipei Medical University-Wan Fang Hospital, Taipei, Taiwan (China)] [Division of Pulmonary Medicine, Department of Internal Medicine, Taipei Medical University-Wan Fang Hospital, Taipei, Taiwan (China); Bien, Mauo-Ying [School of Respiratory Therapy, Taipei Medical University, Taipei Taiwan (China) [School of Respiratory Therapy, Taipei Medical University, Taipei Taiwan (China); Division of Pulmonary Medicine, Department of Internal Medicine, Taipei Medical University-Wan Fang Hospital, Taipei, Taiwan (China); Yang, Shun-Fa [Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan (China) [Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan (China); Department of Medical Research, Chung Shan Medical University Hospital, Taichung, Taiwan (China); Chien, Ming-Hsien, E-mail: mhchien1976@gmail.com [Graduate Institute of Clinical Medicine, Taipei Medical University, Taipei, Taiwan (China)] [Graduate Institute of Clinical Medicine, Taipei Medical University, Taipei, Taiwan (China)

    2012-05-15

    The induction of matrix metalloproteinase (MMP)-9 is particularly important for the invasiveness of various cancer cells. Osthole, a natural coumarin derivative extracted from traditional Chinese medicines, is known to inhibit the proliferation of a variety of tumor cells, but the effect of osthole on the invasiveness of tumor cells is largely unknown. This study determines whether and by what mechanism osthole inhibits invasion in CL1-5 human lung adenocarcinoma cells. Herein, we found that osthole effectively inhibited the migratory and invasive abilities of CL1-5 cells. A zymographic assay showed that osthole inhibited the proteolytic activity of MMP-9 in CL1-5 cells. Inhibition of migration, invasion, and MMP2 and/or MMP-9 proteolytic activities was also observed in other lung adenocarcinoma cell lines (H1299 and A549). We further found that osthole inhibited MMP-9 expression at the messenger RNA and protein levels. Moreover, a chromatin immunoprecipitation assay showed that osthole inhibited the transcriptional activity of MMP-9 by suppressing the DNA binding activity of nuclear factor (NF)-?B in the MMP-9 promoter. Using reporter assays with point-mutated promoter constructs further confirmed that the inhibitory effect of osthole requires an NF-?B binding site on the MMP-9 promoter. Western blot and immunofluorescence assays demonstrated that osthole inhibited NF-?B activity by inhibiting I?B-? degradation and NF-?B p65 nuclear translocation. In conclusion, we demonstrated that osthole inhibits NF-?B-mediated MMP-9 expression, resulting in suppression of lung cancer cell invasion and migration, and osthole might be a potential agent for preventing the invasion and metastasis of lung cancer. -- Highlights: ? Osthole treatment inhibits lung adenocarcinoma cells migration and invasion. ? Osthole reduces the expression and proteolytic activity of MMP-9. ? Osthole inhibits MMP-9 transcription via suppression of NF-?B binding activity. ? Osthole inhibits I?B? degradation and NF-?B nucleus translocation. ? Osthole suppresses EMT by repressing vimentin and inducing E-cadherin expression.

  9. Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

    SciTech Connect (OSTI)

    Verhaak, Roel GW; Hoadley, Katherine A; Purdom, Elizabeth; Wang, Victoria; Qi, Yuan; Wilkerson, Matthew D; Miller, C Ryan; Ding, Li; Golub, Todd; Mesirov, Jill P; Alexe, Gabriele; Lawrence, Michael; O'Kelly, Michael; Tamayo, Pablo; Weir, Barbara A; Gabriel, Stacey; Winckler, Wendy; Gupta, Supriya; Jakkula, Lakshmi; Feiler, Heidi S; Hodgson, J Graeme; James, C David; Sarkaria, Jann N; Brennan, Cameron; Kahn, Ari; Spellman, Paul T; Wilson, Richard K; Speed, Terence P; Gray, Joe W; Meyerson, Matthew; Getz, Gad; Perou, Charles M; Hayes, D Neil; Network, The Cancer Genome Atlas Research

    2009-09-03

    The Cancer Genome Atlas Network recently cataloged recurrent genomic abnormalities in glioblastoma multiforme (GBM). We describe a robust gene expression-based molecular classification of GBM into Proneural, Neural, Classical, and Mesenchymal subtypes and integrate multidimensional genomic data to establish patterns of somatic mutations and DNA copy number. Aberrations and gene expression of EGFR, NF1, and PDGFRA/IDH1 each define the Classical, Mesenchymal, and Proneural subtypes, respectively. Gene signatures of normal brain cell types show a strong relationship between subtypes and different neural lineages. Additionally, response to aggressive therapy differs by subtype, with the greatest benefit in the Classical subtype and no benefit in the Proneural subtype. We provide a framework that unifies transcriptomic and genomic dimensions for GBM molecular stratification with important implications for future studies.

  10. Simulating QCD at the Physical Point with $N_f=2$ Wilson Twisted Mass Fermions at Maximal Twist

    E-Print Network [OSTI]

    ETM Collaboration; A. Abdel-Rehim; C. Alexandrou; F. Burger; M. Constantinou; P. Dimopoulos; R. Frezzotti; K. Hadjiyiannakou; K. Jansen; C. Kallidonis; B. Kostrzewa; G. Koutsou; M. Mangin-Brinet; M. Petschlies; G. Pientka; G. C. Rossi; C. Urbach; U. Wenger

    2015-07-17

    We present simulations of QCD using Nf=2 dynamical Wilson twisted mass lattice QCD with physical value of the pion mass and at one value of the lattice spacing. Such simulations at ~0.09 fm became possible by adding the clover term to the action. While O(a) improvement is still guaranteed by Wilson twisted mass fermions at maximal twist, the introduction of the clover term reduces cutoff effects related to isospin symmetry breaking. We give results for a set of phenomenologically interesting observables like pseudo-scalar masses and decay constants, quark masses and the anomalous magnetic moments of leptons. We mostly find remarkably good agreement with phenomenology, even though we cannot take the continuum and thermodynamic limits.

  11. Metastatic function of BMP-2 in gastric cancer cells: The role of PI3K/AKT, MAPK, the NF-{kappa}B pathway, and MMP-9 expression

    SciTech Connect (OSTI)

    Kang, Myoung Hee [Graduate School of Medicine, Korea University College of Medicine, Korea University, Seoul 136-705 (Korea, Republic of)] [Graduate School of Medicine, Korea University College of Medicine, Korea University, Seoul 136-705 (Korea, Republic of); Oh, Sang Cheul [Division of Oncology/Hematology, Department of Internal Medicine, Korea University College of Medicine, Korea University, Seoul 136-705 (Korea, Republic of)] [Division of Oncology/Hematology, Department of Internal Medicine, Korea University College of Medicine, Korea University, Seoul 136-705 (Korea, Republic of); Lee, Hyun Joo [Department of Pathology, Korea University College of Medicine, Korea University, Seoul 136-705 (Korea, Republic of)] [Department of Pathology, Korea University College of Medicine, Korea University, Seoul 136-705 (Korea, Republic of); Kang, Han Na; Kim, Jung Lim [Graduate School of Medicine, Korea University College of Medicine, Korea University, Seoul 136-705 (Korea, Republic of)] [Graduate School of Medicine, Korea University College of Medicine, Korea University, Seoul 136-705 (Korea, Republic of); Kim, Jun Suk [Division of Oncology/Hematology, Department of Internal Medicine, Korea University College of Medicine, Korea University, Seoul 136-705 (Korea, Republic of)] [Division of Oncology/Hematology, Department of Internal Medicine, Korea University College of Medicine, Korea University, Seoul 136-705 (Korea, Republic of); Yoo, Young A., E-mail: ydanbi@korea.ac.kr [Brain Korea 21 Program for Biomedical Science, Korea University College of Medicine, Korea University, Seoul 136-705 (Korea, Republic of)

    2011-07-15

    Bone morphogenetic proteins (BMPs) have been implicated in tumorigenesis and metastatic progression in various types of cancer cells, but the role and cellular mechanism in the invasive phenotype of gastric cancer cells is not known. Herein, we determined the roles of phosphoinositide 3-kinase (PI3K)/AKT, extracellular signal-regulated protein kinase (ERK), nuclear factor (NF)-{kappa}B, and matrix metalloproteinase (MMP) expression in BMP-2-mediated metastatic function in gastric cancer. We found that stimulation of BMP-2 in gastric cancer cells enhanced the phosphorylation of AKT and ERK. Accompanying activation of AKT and ERK kinase, BMP-2 also enhanced phosphorylation/degradation of I{kappa}B{alpha} and the nuclear translocation/activation of NF-{kappa}B. Interestingly, blockade of PI3K/AKT and ERK signaling using LY294002 and PD98059, respectively, significantly inhibited BMP-2-induced motility and invasiveness in association with the activation of NF-{kappa}B. Furthermore, BMP-2-induced MMP-9 expression and enzymatic activity was also significantly blocked by treatment with PI3K/AKT, ERK, or NF-{kappa}B inhibitors. Immunohistochemistry staining of 178 gastric tumor biopsies indicated that expression of BMP-2 and MMP-9 had a significant positive correlation with lymph node metastasis and a poor prognosis. These results indicate that the BMP-2 signaling pathway enhances tumor metastasis in gastric cancer by sequential activation of the PI3K/AKT or MAPK pathway followed by the induction of NF-{kappa}B and MMP-9 activity, indicating that BMP-2 has the potential to be a therapeutic molecular target to decrease metastasis.

  12. Nuclear NF-?B Expression Correlates With Outcome Among Patients With Head and Neck Squamous Cell Carcinoma Treated With Primary Chemoradiation Therapy

    SciTech Connect (OSTI)

    Balermpas, Panagiotis [Department of Radiation Therapy and Oncology, J. W. Goethe – University Frankfurt am Main, Frankfurt (Germany)] [Department of Radiation Therapy and Oncology, J. W. Goethe – University Frankfurt am Main, Frankfurt (Germany); Michel, Yvonne [Senckenberg Institute of Pathology, J. W. Goethe – University Frankfurt am Main, Frankfurt (Germany)] [Senckenberg Institute of Pathology, J. W. Goethe – University Frankfurt am Main, Frankfurt (Germany); Wagenblast, Jens [Department of Otorhinolaryngology, J. W. Goethe – University Frankfurt am Main, Frankfurt (Germany)] [Department of Otorhinolaryngology, J. W. Goethe – University Frankfurt am Main, Frankfurt (Germany); Seitz, Oliver [Department of Maxillofacial Surgery, J. W. Goethe – University Frankfurt am Main, Frankfurt (Germany)] [Department of Maxillofacial Surgery, J. W. Goethe – University Frankfurt am Main, Frankfurt (Germany); Sipek, Florian; Rödel, Franz; Rödel, Claus [Department of Radiation Therapy and Oncology, J. W. Goethe – University Frankfurt am Main, Frankfurt (Germany)] [Department of Radiation Therapy and Oncology, J. W. Goethe – University Frankfurt am Main, Frankfurt (Germany); Fokas, Emmanouil, E-mail: emmanouil.fokas@kgu.de [Department of Radiation Therapy and Oncology, J. W. Goethe – University Frankfurt am Main, Frankfurt (Germany)] [Department of Radiation Therapy and Oncology, J. W. Goethe – University Frankfurt am Main, Frankfurt (Germany)

    2013-07-15

    Background: To examine whether nuclear NF-?B expression correlates with outcome in patients with head and neck squamous cell carcinoma (HNSCC) treated with primary chemoradiation therapy (CRT). Methods and Materials: Between 2007 and 2010, 101 patients with locally advanced primary HNSCC were treated with definitive simultaneous CRT. Pretreatment biopsy specimens were analyzed for NF-?B p65 (RelA) nuclear immunoreactivity. A sample was assigned to be positive with more than 5% positive nuclear expression. The predictive relevance of NF-?B and clinicopathologic factors for overall survival (OS), progression-free survival (PFS), local progression-free survival (LPFS), and metastasis-free survival (DMFS) was examined by univariate and multivariate analysis. Results: No significant differences between the groups were observed with regard to age, sex, total radiation dose, fractionation mode, total chemotherapy applied, T stage or grading. Patients with p65 nuclear positive biopsy specimens showed significantly a higher rate of lymph node metastasis (cN2c or cN3 status, P=.034). Within a mean follow-up time of 25 months (range, 2.33-62.96 months) OS, PFS, and DMFS were significantly poorer in the p65 nuclear positive group (P=.008, P=.027, and P=.008, respectively). These correlations remained significant in multivariate analysis. Conclusion: NF-?B/p65 nuclear expression is associated with increased lymphatic and hematogenous tumor dissemination and decreased survival in HNSCC patients treated with primary CRT. Our results may foster further investigation of a predictive relevance of NF-?B/p65 and its role as a suitable target for a molecular-based targeted therapy in HNSCC cancer.

  13. Noise, sign problems, and statistics

    E-Print Network [OSTI]

    Michael G. Endres; David B. Kaplan; Jong-Wan Lee; Amy N. Nicholson

    2011-06-01

    We show how sign problems in simulations of many-body systems can manifest themselves in the form of heavy-tailed correlator distributions, similar to what is seen in electron propagation through disordered media. We propose an alternative statistical approach for extracting ground state energies in such systems, illustrating the method with a toy model and with lattice data for unitary fermions.

  14. Statistical mechanics of the vacuum

    E-Print Network [OSTI]

    Christian Beck

    2012-03-01

    The vacuum is full of virtual particles which exist for short moments of time. In this paper we construct a chaotic model of vacuum fluctuations associated with a fundamental entropic field that generates an arrow of time. The dynamics can be physically interpreted in terms of fluctuating virtual momenta. This model leads to a generalized statistical mechanics that distinguishes fundamental constants of nature.

  15. QUANTUM MECHANICS WITHOUT STATISTICAL POSTULATES

    SciTech Connect (OSTI)

    G. GEIGER; ET AL

    2000-11-01

    The Bohmian formulation of quantum mechanics describes the measurement process in an intuitive way without a reduction postulate. Due to the chaotic motion of the hidden classical particle all statistical features of quantum mechanics during a sequence of repeated measurements can be derived in the framework of a deterministic single system theory.

  16. Gauge Invariance and Fractional Statistics

    E-Print Network [OSTI]

    A. R. P. Lima; R. R. Landim

    2006-10-04

    We present a new $(2+1)$-dimensional field theory showing exotic statistics and fractional spin. This theory is achieved through a redefinition of the gauge field $A_{\\mu}$. New properties are found. Another way to implement the field redefinition is used with the same results obtained.

  17. Statistics and Philosophy Mathematical models and reality

    E-Print Network [OSTI]

    Hennig, Christian

    Statistics and Philosophy Mathematical models and reality Frequentist probabilities The Bayes-frequentist controversy Cluster analysis and truth Model Assumptions and Truth in Statistics Christian Hennig 4 February 2015 Christian Hennig Model Assumptions and Truth in Statistics #12;Statistics and Philosophy

  18. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Marianthi Markatou Department of Statistics, Columbia University "Statistical Model Assessment and Model Choice" Monday, April 22, 2002 at 4 of statistical models is to provide a concise description of the aspects of the data judged relevant

  19. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series VICTOR PANARETOS Department of Statistics University of California, Berkeley On the Statistical Inversion of a Stochastic Radon Transform, thus posing a va- riety of statistical problems. We formulate and study such a problem, one

  20. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES I 1947 cf^^v'^ml STATISTICAL DIGEST NO. 21 Fish Oscar L. Chapman, Secretary FISH AND WILDLIFE SERVICE Albert M. Day, Director Statistical Digest 21 PI^j^IELW' , COHEN FISHERY STATISTICS OF THE UNITED STATES 1947 BY A. W. ANDERSON and E. A. POWER UNITED STATES

  1. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Tailen Hsing Department of Statistics" ************************* Monday, February 4, 2002 at 4:00 pm 133 Eckhart Hall, 5734 S. University Avenue ABSTRACT A generalized U-statistic, n2, Kn1,n2 is a symmetric measurable func- tion. A large class of statistics can be expressed

  2. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES 1959 ^mmi STATISTICAL DIGEST NO. 51 UNITED STATES DEPARTMl of Commercial Fisheries, Donald L. McKernan, Director jPANlELM COHEN FISH AND WILDLIFE SERVICE STATISTICAL DIGEST 51 FISHERY STATISTICS OF THE UNITED STATES 1959 BY E. A. POWER PUBLISHED BY BUREAU OF COMMERCIAL

  3. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Statistics Colloquium JACOB BIEN Department of Statistics Stanford University Sparse Hierarchical Interactions MONDAY, January 23, 2012, at 4:00 PM 133. This makes it easier to study as a statistical estimator. We argue that restricting to hierarchical

  4. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Statistics Colloquium LISA LENDWAY Department of Statistics University of Minnesota Using the Bootstrap to Teach Confidence Intervals in an Introductory Statistics Course THURSDAY, February 2, 2012, at 12:00 PM 110 Eckhart Hall, 5734 S. University Avenue

  5. ROBUST ESTIMATION VIA GENERALIZED L-STATISTICS

    E-Print Network [OSTI]

    Serfling, Robert

    CHAPTER 1 ROBUST ESTIMATION VIA GENERALIZED L-STATISTICS: THEORY, APPLICATIONS, AND PERSPECTIVES ROBERT SERFLING University of Texas at Dallas Abstract: Generalized L-statistics, introduced in Ser ing (1984) and including classical U-statistics and L-statistics, are linear functions based on the ordered

  6. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Statistics Colloquium XIAOFENG SHAO Department of Statistics University of Illinois, Urbana-Champaign Self-Normalization for Time Series MONDAY, May 21, 2012 of a statistic. Or the inference can be conducted by using resampling (e.g. moving block boot- strap

  7. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES 1966 STATISTICAL DIGEST NO. 60 UNITED STATES DEPARTMENT OF THE INTERIOR U.S. FISH AND WILDLIFE SERVICE Bureau of Commercial Fisheries STATISTICAL DIGEST 60 FISHERY STATISTICS OF THE UNITED STATES 1966 BY Charles H. Lyles PUBLISHED BY BUREAU OF COMMERCIAL FISHERIES

  8. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES SH 11 A443X FISH 1948 STATISTICAL DIGEST NO. 22 Fish OF THE INTERIOR, Oscar L. Chapman, Secretary FISH AND WILDLIFE SERVICE, Albert M. Day, Director Statistical Digest 22 FISHERY STATISTICS OF THE UNITED STATES 1948 BY A. W. ANDERSON and E. A. POWER UNITED STATES

  9. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Statistics Colloquium NATESH PILLAI Department of Statistics Harvard University Optimal Scaling vs. Optimal Design of MCMC Algorithms: A Comparison MONDAY their behavior in high dimensions thus constitute an essential part of modern statistical inference

  10. Department: Statistics Course No: STAT 220Q

    E-Print Network [OSTI]

    Alpay, S. Pamir

    Department: Statistics Course No: STAT 220Q Title: Statistical Methods Credits: 3 Contact : Dipak K. Dey WQ: Q Catalog Copy : STAT 220Q. Statistical Methods (Calculus Level) Either semester. Three design, non-parametric procedures. Course Information : A. This course offers instruction in statistical

  11. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series BIN YU Department of Statistics University of California, Berkeley "Embracing Statistical Challenges in the Information Technology Age in most if not all fields of science and engineering and beyond. Statistics as a scientific discipline

  12. Department: Statistics Course No: STAT 110Q

    E-Print Network [OSTI]

    Alpay, S. Pamir

    Department: Statistics Course No: STAT 110Q Title: Elementary Concepts of Statistics Credits: 4 restrictions above. Standard and nonparametric approaches to statistical analysis; exploratory data analysis-sample procedures, regression and correlation. Learning to do statistical analysis on a personal computer

  13. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES 1946 STATISTICAL DIGEST NO, 19 Fish and Wildlike Sekvice L. Chapman, Secretary FISH AND WILDLIFE SERVICE Albert M. Day, Director Statistical Digest 19 FISHERY STATISTICS OF THE UNITED STATES 1946 BY A. W. ANDERSON and E. A. POWER UNITED STATES GOVERNMENT

  14. STATISTICS FOR GRADUATE STUDENTS ONLINE RESOURCES

    E-Print Network [OSTI]

    Fletcher, Robin

    1 STATISTICS FOR GRADUATE STUDENTS ONLINE RESOURCES Introduction to Data Analysis Exploring Data Pitfalls of Data Analysis (or How to Avoid Lies and Damned Lies) Statistics notes and related articles published in British Medical Journal Statistical literacy HyperStat Online Statistics Textbook Electronic

  15. Department: Statistics Course No: STAT 201Q

    E-Print Network [OSTI]

    Alpay, S. Pamir

    Department: Statistics Course No: STAT 201Q Title: Introduction to Statistics II Credits: 3 Contact : Dipak K. Dey WQ: Q Catalog Copy : 201Q. Introduction to Statistics II Either semester. Three credits of no calculus background the ideas and methods of statistics beyond the initial introduction given in STAT100

  16. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES 1945 STATISTICAL DIGEST NO, 18 United States Dejtartment. Krug, Secretary FISH AND WILDLIFE SERVICE Albert M. Day, Director Statistical Digest 18 FISHERY STATISTICS OF THE UNITED STATES 1945 BY A. W. ANDERSON and E. A. POWER UNITED STATES GOVERNMENT PRINTING

  17. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES I 1952 .^£^ STATISTICAL DIGEST NO. 34 Fish and Wildlife McKay, Secretary FISH AND WILDLIFE SERVICE, John L. Farley, Director -iJ^EUW^ .COHEN Statistical Digest 34 FISHERY STATISTICS OF THE UNITED STATES 1952 BY A. W. ANDERSON and E. A. POWER UNITED STATES

  18. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series DEBASHIS MONDAL Department of Statistics University of Chicago Gaussian Random Fields and Spatial Statistics MONDAY, April 12, 2010, at 4. ABSTRACT In recent decades, there has been much progress and interest in spatial statistics

  19. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series ROBERT GROSSMAN Department of Mathematics, Statistics and Computer Science University of Illinois at Chicago Building Statistical Models where the data is stored. Most software to compute statistical and data mining models assumes

  20. Department: Statistics Course No: STAT 243Q

    E-Print Network [OSTI]

    Alpay, S. Pamir

    Department: Statistics Course No: STAT 243Q Title: Design of Experiments Credits: 3 Contact : Dipak statistical software to analize data sets based on the statistical methods developed in this course. B. Two and problem assignments from the textbook. C. Analysis of variance statistical models are the major theme

  1. FISHERY STATISTICS F THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS »F THE UNITED STATES ^ 1954 ,M^,. 'M' . ' J*"'',-,'i''' ' STATISTICAL DIGEST NO DEPARTMENT OF THE INTERIOR, Fred A. Seaton, Secretary FISH AND WILDLIFE SERVICE PANIELM. COHEN Statistical Digest 39 FISHERY STATISTICS OF THE UNITED STATES 1954 BY A. W. ANDERSON and E. A. POWER UNITED STATES

  2. Department: Statistics Course No: STAT 100Q

    E-Print Network [OSTI]

    Alpay, S. Pamir

    Department: Statistics Course No: STAT 100Q Title: Introduction to Statistics Credits: 4 Contact above. A standard approach to statistical analysis primarily for students of business and economics and correlation, exploratory data analysis. Learning to do statistical analysis on a personal computer

  3. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics SUMMER Seminar Series SONJA PETROVIC Department of Statistics Pennsylvania State University Algebraic Statistics for Random Graph Models MONDAY, August 8, 2011, at 4:00 PM 110 Eckhart Hall, 5734 S. University Avenue ABSTRACT Algebraic statistics has flourished

  4. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Statistics Colloquium SEBASTIEN ROCH Department. An important issue in this context is the fundamental trade-off between statistical accuracy and computational how this probabilistic perspective produces a finer theoretical understanding of the statistical

  5. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series YALI AMIT Departments of Statistics and Computer Science The University of Chicago Statistical Models in Computer Vision MONDAY of configurations. I will present an approach which starts from simple statistical models for individual objects

  6. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Statistics Colloquium Series PATRICK J. WOLFE Department of Statistics Harvard University Modeling Network Data MONDAY, October 10, 2011, at 4:00 PM 133 Networks are fast becoming a primary object of interest in statistical data analysis, with important

  7. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Samuel Kou Department of Statistics statistical modeling and inference effort. This paper provides the first likelihood-based analysis statistical techniques to the analysis of data produced by modern technologies. This work is joint with Sunney

  8. Statistical Signal Processing Debasis Kundu 1

    E-Print Network [OSTI]

    Kundu, Debasis

    Statistical Signal Processing Debasis Kundu 1 Signal processing may broadly be considered, statistical techniques play an important role in signal processing. Statistics is used in the formulation for estimation of model parameters, and the assessment of model performances. Statistical Signal Processing

  9. LIDIA REJTO Statistics Program, Department of FREC

    E-Print Network [OSTI]

    Rejtõ, Lídia

    L´IDIA REJTO Statistics Program, Department of FREC CANR, University of Delaware 214 Townsend Hall package. Familiar with statistical softwares R, S-Plus, BMDP, SAS, MINITAB. PROFESSIONAL EXPERIENCES Permanent Position: Full Professor, Director of Statistical Laboratory, Statistics Program, Department

  10. Please cite this article in press as: Buyantuyev, A., et al., Multiscale analysis of the urbanization pattern of the Phoenix metropolitan landscape of USA: Time, space and thematic resolution. Landscape Urban Plan. (2009), doi:10.1016/j.landurbplan.2009.1

    E-Print Network [OSTI]

    Wu, Jianguo "Jingle"

    2009-01-01

    of the urbanization pattern of the Phoenix metropolitan landscape of USA: Time, space and thematic resolution of the urbanization pattern of the Phoenix metropolitan landscape of USA: Time, space and thematic resolution of land-cover dynam- ics. Quantification of land-use/land-cover change in Phoenix, Arizona during

  11. Graduate Certificate in Applied Statistics Earn a graduate certificate in Applied Statistics

    E-Print Network [OSTI]

    Frey, Jesse C.

    Graduate Certificate in Applied Statistics Earn a graduate certificate in Applied Statistics from their statistical knowledge and demonstrate their expertise in statistics beyond the undergraduate level. Program in programs that utilize statistics. Admission Requirements Applicants must submit an application, a statement

  12. STATISTICAL MECHANICS PRACTICE EXAM 2005

    E-Print Network [OSTI]

    Dorlas, Teunis C.

    STATISTICAL MECHANICS PRACTICE EXAM 2005 Time allotted: 3 hours for 5 questions. 1. (i) Give density of a system of independent spins si = ±1 with energy levels given by E(s1, . . . , sN ) = -H N i=1 si. 2. (i) Derive the expression f() = - 1 ln eJ cosh H + e2J sinh2 H + e-2J for the free energy

  13. Statistically significant relational data mining :

    SciTech Connect (OSTI)

    Berry, Jonathan W.; Leung, Vitus Joseph; Phillips, Cynthia Ann; Pinar, Ali; Robinson, David Gerald; Berger-Wolf, Tanya; Bhowmick, Sanjukta; Casleton, Emily; Kaiser, Mark; Nordman, Daniel J.; Wilson, Alyson G.

    2014-02-01

    This report summarizes the work performed under the project (3z(BStatitically significant relational data mining.(3y (BThe goal of the project was to add more statistical rigor to the fairly ad hoc area of data mining on graphs. Our goal was to develop better algorithms and better ways to evaluate algorithm quality. We concetrated on algorithms for community detection, approximate pattern matching, and graph similarity measures. Approximate pattern matching involves finding an instance of a relatively small pattern, expressed with tolerance, in a large graph of data observed with uncertainty. This report gathers the abstracts and references for the eight refereed publications that have appeared as part of this work. We then archive three pieces of research that have not yet been published. The first is theoretical and experimental evidence that a popular statistical measure for comparison of community assignments favors over-resolved communities over approximations to a ground truth. The second are statistically motivated methods for measuring the quality of an approximate match of a small pattern in a large graph. The third is a new probabilistic random graph model. Statisticians favor these models for graph analysis. The new local structure graph model overcomes some of the issues with popular models such as exponential random graph models and latent variable models.

  14. Parallel auto-correlative statistics with VTK.

    SciTech Connect (OSTI)

    Pebay, Philippe Pierre; Bennett, Janine Camille

    2013-08-01

    This report summarizes existing statistical engines in VTK and presents both the serial and parallel auto-correlative statistics engines. It is a sequel to [PT08, BPRT09b, PT09, BPT09, PT10] which studied the parallel descriptive, correlative, multi-correlative, principal component analysis, contingency, k-means, and order statistics engines. The ease of use of the new parallel auto-correlative statistics engine is illustrated by the means of C++ code snippets and algorithm verification is provided. This report justifies the design of the statistics engines with parallel scalability in mind, and provides scalability and speed-up analysis results for the autocorrelative statistics engine.

  15. Metropolitan Transportation Plan 2035 

    E-Print Network [OSTI]

    Tyler Area Metropolitan Planning Organization

    2009-12-04

    and vertical concentration distributions with the assumptions of continuous emissions, conservation of mass, steady-state conditions, and normal distribution of crosswind and vertical concentrations of pollutants (Cooper and Alley, 2002). The Gaussian...

  16. Lubbock Metropolitan Transportation Plan 

    E-Print Network [OSTI]

    Lubbock Metropolitan Planning Organization

    2007-09-18

    ..............................................................................................................................40 Marsha Sharp Freeway (US 62/82) ...............................................................................................40 Ports-To-Plains Corridor...

  17. Manchester Metropolitan University Sustainability

    E-Print Network [OSTI]

    to create a sustainable University with a positive environmental impact" First Class Environmental and environmental impact. · We've installed two green roofs on our All Saints building to help reduce the risk "Working together to create a sustainable University with a positive environmental impact" First Class

  18. MANCHESTER METROPOLITAN Financial Statements

    E-Print Network [OSTI]

    (includes share of associated company's result) (199,979) (185,386) Impairment on properties in an impairment charge of £7.7m The University has during the past year been planning the implementation of six seven campus areas down to three and will ensure the University has a sustainable estate for the future

  19. Statistical Models for Globular Cluster Luminosity Distribution

    E-Print Network [OSTI]

    Hunter, David

    Statistical Models for Globular Cluster Luminosity Distribution Max Buot Donald Richards Xavier statistical models which have been proposed for luminosity distributions for the globular clusters galaxies were well fit by Gaussian distributions, subsequent investigations suggested

  20. Statistics on pattern-avoiding permutations

    E-Print Network [OSTI]

    Elizalde, Sergi, 1979-

    2004-01-01

    This thesis concerns the enumeration of pattern-avoiding permutations with respect to certain statistics. Our first result is that the joint distribution of the pair of statistics 'number of fixed points' and 'number of ...

  1. Statistics Department University of California, Berkeley

    E-Print Network [OSTI]

    California at Santa Cruz, University of

    John Rice Statistics Department University of California, Berkeley Joint work with Peter Bickel problem Barycentric corrected arrival times 0 Energy, no matter how rich the dictionary from which you adaptively compose a detection statistic, no matter how

  2. |Research Focus Statistical decision theory and evolution

    E-Print Network [OSTI]

    Maloney, Laurence T.

    |Research Focus Statistical decision theory and evolution Laurence T. Maloney Department recent articles by Geisler and Diehl use Bayesian statistical decision theory to model the co, an advantage that ultimately translates into `reproductive success'. The balance between predator and prey

  3. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar D. R. Bellhouse Department of Statistical and Actuarial Sciences University of Western Ontario London, Ontario Canada N6A 5B7 "Lord Stanhope

  4. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Noureddine El Karoui Department of Statistics Stanford University "The Tracy-Widom Law Holds When n, p, p/n , with Application to PCA" Monday

  5. A Carto Dashboard for Distributed Statistical Data

    E-Print Network [OSTI]

    for Statistical Data From Statistics Netherlands (CBS) - Open Data, API using ODATA standard - To be combined, different aggregation in time: same variable, different times in theme: same place and time, different

  6. Seismic Attribute Analysis Using Higher Order Statistics 

    E-Print Network [OSTI]

    Greenidge, Janelle Candice

    2009-05-15

    Seismic data processing depends on mathematical and statistical tools such as convolution, crosscorrelation and stack that employ second-order statistics (SOS). Seismic signals are non-Gaussian and therefore contain information beyond SOS. One...

  7. Transportation Statistics Annual Report 1997

    SciTech Connect (OSTI)

    Fenn, M.

    1997-01-01

    This document is the fourth Transportation Statistics Annual Report (TSAR) prepared by the Bureau of Transportation Statistics (BTS) for the President and Congress. As in previous years, it reports on the state of U.S. transportation system at two levels. First, in Part I, it provides a statistical and interpretive survey of the system—its physical characteristics, its economic attributes, aspects of its use and performance, and the scale and severity of unintended consequences of transportation, such as fatalities and injuries, oil import dependency, and environment impacts. Part I also explores the state of transportation statistics, and new needs of the rapidly changing world of transportation. Second, Part II of the report, as in prior years, explores in detail the performance of the U.S. transportation system from the perspective of desired social outcomes or strategic goals. This year, the performance aspect of transportation chosen for thematic treatment is “Mobility and Access,” which complements past TSAR theme sections on “The Economic Performance of Transportation” (1995) and “Transportation and the Environment” (1996). Mobility and access are at the heart of the transportation system’s performance from the user’s perspective. In what ways and to what extent does the geographic freedom provided by transportation enhance personal fulfillment of the nation’s residents and contribute to economic advancement of people and businesses? This broad question underlies many of the topics examined in Part II: What is the current level of personal mobility in the United States, and how does it vary by sex, age, income level, urban or rural location, and over time? What factors explain variations? Has transportation helped improve people’s access to work, shopping, recreational facilities, and medical services, and in what ways and in what locations? How have barriers, such as age, disabilities, or lack of an automobile, affected these accessibility patterns? How are commodity flows and transportation services responding to global competition, deregulation, economic restructuring, and new information technologies? How do U.S. patterns of personal mobility and freight movement compare with other advanced industrialized countries, formerly centrally planned economies, and major newly industrializing countries? Finally, how is the rapid adoption of new information technologies influencing the patterns of transportation demand and the supply of new transportation services? Indeed, how are information technologies affecting the nature and organization of transportation services used by individuals and firms?

  8. On statistics of molecular chaos

    E-Print Network [OSTI]

    Yuriy Kuzovlev

    2009-11-03

    It is shown that the BBGKY equations for a particle interacting with ideal gas imply exact relations between probability distribution of path of the particle, its derivatives in respect to the gas density and irreducible many-particle correlations of gas atoms with the path. These relations visualize that the correlations of any order always significantly contribute to evolution of the path distribution, so that the exact statistical mechanics theory does not reduce to the classical kinetics even in the low-density (or Boltzmann-Grad) limit.

  9. 2008 world direct reduction statistics

    SciTech Connect (OSTI)

    NONE

    2009-07-01

    This supplement discusses total direct reduced iron (DRI) production for 2007 and 2008 by process. Total 2008 production by MIDREX(reg sign) direct reduction process plants was over 39.8 million tons. The total of all coal-based processes was 17.6 million tons. Statistics for world DRI production are also given by region for 2007 and 2008 and by year (1970-2009). Capacity utilization for 2008 by process is given. World DRI production by region and by process is given for 1998-2008 and world DRI shipments are given from the 1970s to 2008. A list of world direct reduction plants is included.

  10. ARM - Historical Field Campaign Statistics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Comments? WeDatastreamstps DocumentationAtlanticENAField ParticipantsField Campaign Statistics 2015 Quarterly

  11. Inhibition of inflammatory mediators contributes to the anti-inflammatory activity of KYKZL-1 via MAPK and NF-?B pathway

    SciTech Connect (OSTI)

    Xu, Guang-Lin [Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing (China); Department of Pharmacology, University of Michigan, Ann Arbor (United States); Du, Yi-Fang; Cheng, Jing; Huan, Lin [Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing (China); Chen, Shi-Cui [Jinhu Food and Drug Administration, Jiangsu (China); Wei, Shao-Hua [College of Chemistry and Materials Science, Nanjing Normal University, Nanjing (China); Gong, Zhu-Nan, E-mail: biopharmacology@126.com [Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing (China); Cai, Jie; Qiu, Ting; Wu, Hao; Sun, Ting [Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing (China); Ao, Gui-Zhen [Department of Medicinal Chemistry, School of Pharmacy, Soochow University, Jiangsu (China)

    2013-10-01

    KYKZL-1, a newly synthesized compound with COX/5-LOX dual inhibition, was subjected to the anti-inflammatory activity test focusing on its modulation of inflammatory mediators as well as intracellular MAPK and NF-?B signaling pathways. In acute ear edema model, pretreatment with KYKZL-1 (p.o.) dose-dependently inhibited the xylene-induced ear edema in mice with a higher inhibition than diclofenac. In a three-day TPA-induced inflammation, KYKZL-1 also showed significant anti-inflammatory activity with inhibition ranging between 20% and 64%. In gastric lesion test, KYKZL-1 elicited markedly fewer stomach lesions with a low index of ulcer as compared to diclofenac in rats. In further studies, KYKZL-1 was found to significantly inhibit the production of NO, PGE{sub 2}, LTB{sub 4} in LPS challenged RAW264.7, which is parallel to its attenuation of the expression of iNOS, COX-2, 5-LOX mRNAs or proteins and inhibition of phosphorylation of p38 and ERK MAPKs and activation of NF-?B. Taken together, our data indicate that KYKZL-1 comprises dual inhibition of COX and 5-LOX and exerts an obvious anti-inflammatory activity with an enhanced gastric safety profile via simultaneous inhibition of phosphorylation of p38 and ERK MAPKs and activation of NF-?B. - Highlights: • KYKZL-1 is designed to exhibit COX/5-LOX dual inhibition. • KYKZL-1 inhibits NO, PGE{sub 2} and LTB{sub 4} and iNOS, COX-2 and 5-LOX mRNAs and MAPKs. • KYKZL-1 inhibits phosphorylation of MAPKs. • KYKZL-1 inactivates NF-?B pathway.

  12. D O M A I NF A L L 2 0 0 4 55555 How a Top Secret Satellite and Fast-Thinking

    E-Print Network [OSTI]

    D O M A I NF A L L 2 0 0 4 55555 How a Top Secret Satellite and Fast-Thinking Navy and Air Force man in the Navy who had worked directly with the top secret Corona Air Force spy satellite, knew what the weather at the Pacific Ocean splashdown site. "When I arrived in Hawaii, I still had my top secret

  13. Moderate extracellular acidification inhibits capsaicin-induced cell death through regulating calcium mobilization, NF-{kappa}B translocation and ROS production in synoviocytes

    SciTech Connect (OSTI)

    Hu, Fen; Yang, Shuang; Zhao, Dan; Zhu, Shuyan; Wang, Yuxiang; Li, Junying

    2012-07-20

    Highlights: Black-Right-Pointing-Pointer Moderate extracellular acidification regulates intracellular Ca{sup 2+} mobilization. Black-Right-Pointing-Pointer Moderate acidification activates NF-{kappa}B nuclear translocation in synoviocytes. Black-Right-Pointing-Pointer Moderate acidification depresses the ROS production induced by capsaicin. Black-Right-Pointing-Pointer Moderate acidification inhibits capsaicin-caused synoviocyte death. -- Abstract: We previously show the expression of transient receptor potential vanilloid 1 (TRPV1) in primary synoviocytes from collagen-induced arthritis (CIA) rats. Capsaicin and lowered extracellular pH from 7.4 to 5.5 induce cell death through TRPV1-mediated Ca{sup 2+} entry and reactive oxygen species (ROS) production. However, under the pathological condition in rheumatoid arthritis, the synovial fluid is acidified to a moderate level (about pH 6.8). In the present study, we examined the effects of pH 6.8 on the TRPV1-mediated cell death. Our finding is different or even opposite from what was observed at pH 5.5. We found that the moderate extracellular acidification (from pH 7.4 to 6.8) inhibited the capsaicin-induced Ca{sup 2+} entry through attenuating the activity of TRPV1. In the mean time, it triggered a phospholipse C (PLC)-related Ca{sup 2+} release from intracellular stores. The nuclear translocation of NF-{kappa}B was found at pH 6.8, and this also depends on PLC activation. Moreover, the capsaicin-evoked massive ROS production and cell death were depressed at pH 6.8, both of which are dependent on the activation of PLC and NF-{kappa}B. Taken together, these results suggested that the moderate extracellular acidification inhibited the capsaicin-induced synoviocyte death through regulating Ca{sup 2+} mobilization, activating NF-{kappa}B nuclear translocation and depressing ROS production.

  14. Purdue VIGRE REU in Mathematics and Statistics

    E-Print Network [OSTI]

    Research Experience for Undergraduates. at the. Departments of Mathematics and Statistics Purdue Univeristy, West Lafayette, Indiana Summer 2003.

  15. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    of Statistics Harvard University "Equi-energy Sampler: From Statistical Inference to Statistical Mechanics the seminar in Eckhart 110. ABSTRACT We introduce a new sampling algorithm, the equi-energy sampler, the equi-energy sampler, utilizing the temperature-energy duality, targets the energy directly. The focus

  16. STORM: A STatistical Object Representation Model

    SciTech Connect (OSTI)

    Rafanelli, M. ); Shoshani, A. )

    1989-11-01

    In this paper we explore the structure and semantic properties of the entities stored in statistical databases. We call such entities statistical objects'' (SOs) and propose a new statistical object representation model,'' based on a graph representation. We identify a number of SO representational problems in current models and propose a methodology for their solution. 11 refs.

  17. Quantrum chaos and statistical nuclear physics

    SciTech Connect (OSTI)

    Not Available

    1986-01-01

    This book contains 33 selections. Some of the titles are: Chaotic motion and statistical nuclear theory; Test of spectrum and strength fluctuations with proton resonances; Nuclear level densities and level spacing distributions; Spectral statistics of scale invariant systems; and Antiunitary symmetries and energy level statistics.

  18. TIGHT BOUNDS ON EXPECTED ORDER STATISTICS

    E-Print Network [OSTI]

    Bertsimas, Dimitris

    TIGHT BOUNDS ON EXPECTED ORDER STATISTICS DIIIMMMIIITTTRRRIIISSS BEEERRRTTTSSSIIIMMMAAASSS Sloan@nus.edu.sg In this article, we study the problem of finding tight bounds on the expected value of the kth-order statistic E of the highest-order statistic E @Xn:n# can be computed with a bisection search algo- rithm+ An extremal discrete

  19. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series SOURAV CHATTERJEE Department of Statistics University of California, Berkeley "Some extensions of Stein's method" MONDAY, February 20, 2006 dependence models of statistical physics and combinatorics will be worked out. Please send email to Mathias

  20. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series DAVID VAN DYK Department of Statistics University of California, Irvine "Highly Structured Models in High Energy Astrophysics" MONDAY in Eckhart 110. ABSTRACT In recent years, an important new trend has been growing in applied statistics

  1. Department: Statistics Course No: STAT 242Q

    E-Print Network [OSTI]

    Alpay, S. Pamir

    Department: Statistics Course No: STAT 242Q Title: Analysis of Experiments Credits: 3 Contact Information : A. The objective of this course is to introduce students to statistical data analysis using will obtain hands-on experience with analyzing data usign statistical models, such as regression and analysis

  2. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series REGINA LIU Department of Statistics Rutgers, The State University of New Jersey Mining and Tracking Massive Text Data MONDAY, April 9 datasets to discover useful features and develop tracking statistics (often referred to as performance

  3. June 1, 2015 DEPARTMENT OF MATHEMATICS, STATISTICS

    E-Print Network [OSTI]

    June 1, 2015 DEPARTMENT OF MATHEMATICS, STATISTICS AND COMPUTER SCIENCE Limited Term Position The Department of Mathematics, Statistics and Computer Science at St. Francis Xavier University invites, 2016. Applicants should hold a PhD (or a nearly completed PhD) in Mathematics or Statistics

  4. Statistics and Causal Inference PAUL W. HOLLAND*

    E-Print Network [OSTI]

    Fitelson, Branden

    Statistics and Causal Inference PAUL W. HOLLAND* Problems involving causal inference have dogged conclusions drawn from a carefully designed experiment are often valid. What can a statistical model say about in the most unexpected places, for example, "If the statistics cannot relate cause and effect, they can

  5. Department: Statistics Course number: STAT 202W

    E-Print Network [OSTI]

    Alpay, S. Pamir

    Department: Statistics Course number: STAT 202W Title: Undergraduate Seminar II Credits: 1 Contact, and choose one statistical topic to investigate in detail. The student will write a well revised will attend 6-8 seminars per semester, and choose one statistical topic to investigate in detail. The student

  6. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series NANCY R. ZHANG Department of Statistics Stanford University Simultaneous Scans of Multiple Sequences for Shared Variant Intervals MONDAY in Eckhart 110. ABSTRACT We examine the statistical problem of simultaneous detection in multiple sequences

  7. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seventh Annual Bahadur Memorial Lectures ELIZABETH A. THOMPSON Department of Statistics University of Washington "Monte Carlo Likelihood Inference, the statistics of primary importance for estimation and testing are functions of unobservable latent vari- ables

  8. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series MARC HALLIN Universit´e libre de the seminar in Eckhart 110. ABSTRACT The modern history of ranks in statistics started in 1945 with Frank, Lehmann, Hajek, and Le Cam, rank-based methods have followed the devel- opment of contemporary statistics

  9. Department: Statistics Course No: STAT 272Q

    E-Print Network [OSTI]

    Alpay, S. Pamir

    Department: Statistics Course No: STAT 272Q Title: Introduction to Biostatistics Credits: 3 Contact-analysis. Course Information : A. The goal is to introduce the students to the modern statistical methods in modeling analysis of data in biological and medical sciences. Teach the students the use of statistical

  10. WhartonDepartment of Statistics Data Mining

    E-Print Network [OSTI]

    Stine, Robert A.

    WhartonDepartment of Statistics Data Mining Introduction Bob Stine Dept of Statistics What is data mining? · An insult? · Predictive modeling · Large, wide data sets, often unstructuredDepartment of Statistics Plan · Week 1 · Data mining with regression, logistic regression · Illustrate key ideas

  11. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series GILLES BLANCHARD Associate researcher, Fraunhofer FIRST (IDA) "Statistical Performance of Support Vector Machines" MONDAY, January 29 in Eckhart 110. ABSTRACT I will present a contribution to the statistical analysis of Support Vector Machines

  12. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series YACINE AIT-SAHALIA Bendheim Refreshments following the seminar in Eckhart 110. ABSTRACT We propose statistical tests to discriminate frequency. The two statistics allow for a symmetric treatment of the problem: we can either take the null

  13. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series VENKAT CHANDRASEKARAN Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology Statistical Modeling over is motivated by the following question: Suppose we have sample statistics of only a subset of a collection

  14. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series MURAD S. TAQQU Department of Mathematics and Statistics Boston University Self-Similarity and Computer Network Traffic MONDAY, November 8 in Eckhart 110. ABSTRACT Ethernet local area network traffic appears to be approximately statistically self

  15. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics BAHADUR MEMORIAL LECTURES JAMES O. BERGER Department of Statistical Science Duke University "I don't know where I'm gonna go when the volcano blows of mathematical computer modeling, statistical modeling of geophysical data, and extreme-event probability

  16. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seventh Annual Bahadur Memorial Lectures ELIZABETH A. THOMPSON Department of Statistics University of Washington "Uncertainty and Evidence introduced into the statistics literature as a way to describe the uncertainty inherent in a randomized test

  17. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series DAN NICOLAE Department of Statistics The University of Chicago "Quantifying Correlation with Applications to Genome-Wide Association of the statistical issues involved including the need for multi-locus analyses and allowing for environmental risk

  18. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series MATHIAS DRTON Department of Statistics The University of Chicago "Algebraic Factor Analysis: Tetrads, Pentads and Beyond" MONDAY, January in Eckhart 110. ABSTRACT Abstract: Factor analysis refers to a statistical model in which observed variables

  19. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series WEI BIAO WU Department of Statistics The University of Chicago "What is dependence?" MONDAY, March 27, 2006 at 4:00 PM 133 Eckhart Hall of random processes, dependence is the rule rather than the exception. To facilitate the related statistical

  20. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series YING NIAN WU Department of Statistics University of California at Los Angeles "Scale in Natural Scene Image Understanding" MONDAY textures that are often summarized by feature statistics. Although these two classes of patterns appear

  1. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Linda B. Collins Department of Statistics University of Chicago "Issues in Catastrophe Excess-of-Loss Reinsurance Pricing" Monday, December distribution. We discuss the general statistical ideas behind these proprietary models and examine some

  2. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series DANIEL J. SCHAID Mayo Clinic-control studies of candidate genes, we develop a new class of nonparametric statistics that can simultaneously test the association of multiple marker loci with disease. Our approach is based on U-statistics, which

  3. CAPES 2013 PROBABILITY and STATISTICS Ttulo ISSN

    E-Print Network [OSTI]

    Moreira, Carlos Gustavo

    -0918 Communications Series A1 Mathematics & Statistics 1303-5911 Computational and mathematical organization theory-5483 Communications in Mathematical Physics 0010-3616 Communications in statistics. Simulation and computation 0361 communications in probability 1083-589X Electronic journal of applied statistical analysis 2070-5948 Electronic

  4. Tutorials on AstroStatistics and R

    E-Print Network [OSTI]

    Wolfe, Patrick J.

    Tutorials on AstroStatistics and R by Eric Feigelson Jan 29 and Jan 31, 2014 Phillips Auditorium in astronomical research [general interest lecture] 10:00am - 11:00am : Introduction to the R statistical software language [lecture & practicum] 11:00am - 2:30pm : break [EF available for informal statistical consulting

  5. Unsupervised Segmentation for Statistical Machine Translation

    E-Print Network [OSTI]

    Koehn, Philipp

    Unsupervised Segmentation for Statistical Machine Translation Siriwan Sereewattana TH E U N I V E R for statistical machine translation. The approach requires no language- nor domain-specific knowledge whatsoever in principle the statistical framework of machine translation can be ap- plied to any language pair

  6. EPSRC CASE Studentship Statistical Modelling of Fingerprints

    E-Print Network [OSTI]

    Oakley, Jeremy

    and mathematics together with experience or strong interest in statistical computing (including programming in R1 EPSRC CASE Studentship Statistical Modelling of Fingerprints SUMMARY This CASE studentship involves working with researchers in the Statistics & Interpretation Group of the Forensic Science Service

  7. General Database Statistics Using Entropy Maximization

    E-Print Network [OSTI]

    Suciu, Dan

    (z) Estimate: q(y) :- R(x, y), S(y, z) Fig. 1. An example of a Statistical Program and a query, q whoseGeneral Database Statistics Using Entropy Maximization Raghav Kaushik1 , Christopher R´e2 , and Dan engines. The key object of our study is a statistical program, which is a set of pairs (v, d), where v

  8. Fractional quantum Hall effect and nonabelian statistics

    E-Print Network [OSTI]

    N. Read; G. Moore

    1992-02-03

    It is argued that fractional quantum Hall effect wavefunctions can be interpreted as conformal blocks of two-dimensional conformal field theory. Fractional statistics can be extended to nonabelian statistics and examples can be constructed from conformal field theory. The Pfaffian state is related to the 2D Ising model and possesses fractionally charged excitations which are predicted to obey nonabelian statistics.

  9. ROS and NF-{kappa}B are involved in upregulation of IL-8 in A549 cells exposed to multi-walled carbon nanotubes

    SciTech Connect (OSTI)

    Ye Shefang Wu Yihui; Hou Zhenqing; Zhang Qiqing

    2009-02-06

    Carbon nanotubes (CNTs) have potential applications in biosensors, tissue engineering, and biomedical devices because of their unique physico-chemical, electronic and mechanical properties. However, there is limited literature data available concerning the biological properties and toxicity of CNTs. This study aimed to assess the toxicity exhibited by multi-walled CNTs (MWCNTs) and to elucidate possible molecular mechanisms underlying the biological effects of MWCNTs in A549 cells. Exposing A549 cells to MWCNTs led to cell death, changes in cell size and complexity, reactive oxygen species (ROS) production, interleukin-8 (IL-8) gene expression and nuclear factor (NF)-{kappa}B activation. Treatment of A549 cells with antioxidants prior to adding MWCNTs decreased ROS production and abrogated expression of IL-8 mRNA. Pretreatment of A549 cells with NF-{kappa}B inhibitors suppressed MWCNTs-induced IL-8 mRNA expression. These results indicate that MWCNTs are able to induce expression of IL-8 in A549 cells, at least in part, mediated by oxidative stress and NF-{kappa}B activation.

  10. Lectures on probability and statistics

    SciTech Connect (OSTI)

    Yost, G.P.

    1984-09-01

    These notes are based on a set of statistics lectures delivered at Imperial College to the first-year postgraduate students in High Energy Physics. They are designed for the professional experimental scientist. We begin with the fundamentals of probability theory, in which one makes statements about the set of possible outcomes of an experiment, based upon a complete a priori understanding of the experiment. For example, in a roll of a set of (fair) dice, one understands a priori that any given side of each die is equally likely to turn up. From that, we can calculate the probability of any specified outcome. We finish with the inverse problem, statistics. Here, one begins with a set of actual data (e.g., the outcomes of a number of rolls of the dice), and attempts to make inferences about the state of nature which gave those data (e.g., the likelihood of seeing any given side of any given die turn up). This is a much more difficult problem, of course, and one's solutions often turn out to be unsatisfactory in one respect or another.

  11. Characterization of Fine Particulate Matter (PM) and Secondary PM Precursor Gases in the Mexico City Metropolitan Area

    SciTech Connect (OSTI)

    Molina, Luisa T.; Molina, Mario J.; Volkamer, Rainer; de Foy, Benjamin; Lei, Wenfang; Zavaka, Miguel; Velasco, Erik

    2008-10-31

    This project was one of three collaborating grants funded by DOE/ASP to characterize the fine particulate matter (PM) and secondary PM precursors in the Mexico City Metropolitan Area (MCMA) during the MILAGRO Campaign. The overall effort of MCMA-2006, one of the four components, focused on i) examination of the primary emissions of fine particles and precursor gases leading to photochemical production of atmospheric oxidants and secondary aerosol particles; ii) measurement and analysis of secondary oxidants and secondary fine PM production, with particular emphasis on secondary organic aerosol (SOA), and iii) evaluation of the photochemical and meteorological processes characteristic of the Mexico City Basin. The collaborative teams pursued the goals through three main tasks: i) analyses of fine PM and secondary PM precursor gaseous species data taken during the MCMA-2002/2003 campaigns and preparation of publications; ii) planning of the MILAGRO Campaign and deployment of the instrument around the MCMA; and iii) analysis of MCMA-2006 data and publication preparation. The measurement phase of the MILAGRO Campaign was successfully completed in March 2006 with excellent participation from the international scientific community and outstanding cooperation from the Mexican government agencies and institutions. The project reported here was led by the Massachusetts Institute of Technology/Molina Center for Energy and the Environment (MIT/MCE2) team and coordinated with DOE/ASP-funded collaborators at Aerodyne Research Inc., University of Colorado at Boulder and Montana State University. Currently 24 papers documenting the findings from this project have been published. The results from the project have improved significantly our understanding of the meteorological and photochemical processes contributing to the formation of ozone, secondary aerosols and other pollutants. Key findings from the MCMA-2003 include a vastly improved speciated emissions inventory from on-road vehicles: the MCMA motor vehicles produce abundant amounts of primary PM, elemental carbon, particle-bound polycyclic aromatic hydrocarbons, carbon monoxide and a wide range of air toxics; the feasibility of using eddy covariance techniques to measure fluxes of volatile organic compounds in an urban core and a valuable tool for validating local emissions inventory; a much better understanding of the sources and atmospheric loadings of volatile organic compounds; the first spectroscopic detection of glyoxal in the atmosphere; a unique analysis of the high fraction of ambient formaldehyde from primary emission sources; characterization of ozone formation and its sensitivity to VOCs and NOx; a much more extensive knowledge of the composition, size distribution and atmospheric mass loadings of both primary and secondary fine PM, including the fact that the rate of MCMA SOA production greatly exceeded that predicted by current atmospheric models; evaluations of significant errors that can arise from standard air quality monitors for O3 and NO2; and the implementation of an innovative Markov Chain Monte Carlo method for inorganic aerosol modeling as a powerful tool to analyze aerosol data and predict gas phase concentrations where these are unavailable. During the MILAGRO Campaign the collaborative team utilized a combination of central fixed sites and a mobile laboratory deployed throughout the MCMA to representative urban and boundary sites to measure trace gases and fine particles. Analysis of the extensive 2006 data sets has confirmed the key findings from MCMA-2002/2003; additionally MCMA-2006 provided more detailed gas and aerosol chemistry and wider regional scale coverage. Key results include an updated 2006 emissions inventory; extension of the flux system to measure fluxes of fine particles; better understanding of the sources and apportionment of aerosols, including contribution from biomass burning and industrial sources; a comprehensive evaluation of metal containing particles in a com

  12. Broken Valence Chiral Symmetry and Chiral Polarization of Dirac Spectrum in N$_f$=12 QCD at Small Quark Mass

    E-Print Network [OSTI]

    Andrei Alexandru; Ivan Horváth

    2014-12-04

    The validity of recently proposed equivalence between valence spontaneous chiral symmetry breaking (vSChSB) and chiral polarization of low energy Dirac spectrum (ChP) in SU(3) gauge theory, is examined for the case of twelve mass-degenerate fundamental quark flavors. We find that the vSChSB-ChP correspondence holds for regularized systems studied. Moreover, our results suggest that vSChSB occurs in two qualitatively different circumstances: there is a quark mass $m_c$ such that for $m > m_c$ the mode condensing Dirac spectrum exhibits standard monotonically increasing density, while for $m_{ch} < m < m_c$ the peak around zero separates from the bulk of the spectrum, with density showing a pronounced depletion at intermediate scales. Valence chiral symmetry restoration may occur at yet smaller masses $m < m_{ch}$, but this has not yet been seen by overlap valence probe, leaving the $m_{ch}=0$ possibility open. The latter option could place massless N$_f$=12 theory outside of conformal window. Anomalous behavior of overlap Dirac spectrum for $m_{ch} < m < m_c$ is qualitatively similar to one observed previously in zero and few-flavor theories as an effect of thermal agitation.

  13. CEAL Statistics 2009-2010: an Overview

    E-Print Network [OSTI]

    Doll, Vickie

    2011-02-01

    stream_size 15289 stream_content_type text/plain stream_name DOLL_CEAL statistics 2009-2010_ an overview.pdf.txt stream_source_info DOLL_CEAL statistics 2009-2010_ an overview.pdf.txt Content-Encoding UTF-8 Content-Type text... outsourced acquisition. Our sincere thanks to those 50 libraries that participated in the 2010 survey. Vickie Fu Doll Chair, CEAL Statistics University of Kansas CEAL Statistics Database: http://lib.ku.edu/ceal/php CEAL Statistics Homepage...

  14. Statistics for Teachers: STAT 4/6070 The UGA Statistics Department has been

    E-Print Network [OSTI]

    Hall, Daniel

    Statistics for Teachers: STAT 4/6070 The UGA Statistics Department has been teaching a second course in statistics for mathematics education students since 1998. The course is designed to prepare pre-service and in-service high school mathematics teachers to teach the statistical concepts that appear

  15. Statistics Page 235Sonoma State University 2015-2016 Catalog DEPARTMENT OF MATHEMATICS AND STATISTICS

    E-Print Network [OSTI]

    Ravikumar, B.

    Statistics Page 235Sonoma State University 2015-2016 Catalog STATISTICS DEPARTMENT OF MATHEMATICS AND STATISTICS Darwin Hall 114 phone: (707) 664-2368 email: math@sonoma.edu www.sonoma.edu/math DEPARTMENT CHAIR Brigitte Lahme STATISTICS PROGRAM ADVISORS Susan Herring Elaine Newman ADMINISTRATIVE COORDINATORS Whitney

  16. Branden Fitelson Remarks on the Philosophy of Statistics 0 SOME REMARKS ON THE PHILOSOPHY OF STATISTICS

    E-Print Network [OSTI]

    Fitelson, Branden

    Branden Fitelson Remarks on the Philosophy of Statistics 0 SOME REMARKS ON THE PHILOSOPHY OF STATISTICS BRANDEN FITELSON Department of Philosophy San Jos´e State University branden@fitelson.org http of Statistics 1 Overview of Presentation · What are the ends of statistical experiment, analysis

  17. Developing Your Statistics The Statistics tab is used to display statistics for some or all of your collected samples. You will need at least one sample

    E-Print Network [OSTI]

    Developing Your Statistics The Statistics tab is used to display statistics for some or all of your collected samples. You will need at least one sample and a plot to view statistics. Select Samples Select. are displayed and the statistics are added to the Master Statistics Table. Uncheck samples to remove them from

  18. Workforce Statistics - NA SH | National Nuclear Security Administratio...

    National Nuclear Security Administration (NNSA)

    Us Our Operations Management and Budget Office of Civil Rights Workforce Statistics Workforce Statistics - NA SH Workforce Statistics - NA SH NA SH FY14 Year End...

  19. Workforce Statistics - NA 00 | National Nuclear Security Administratio...

    National Nuclear Security Administration (NNSA)

    Us Our Operations Management and Budget Office of Civil Rights Workforce Statistics Workforce Statistics - NA 00 Workforce Statistics - NA 00 NA 00 FY14 Semi Annual...

  20. Involvement of a chromatin modifier in response to mono-(2-ethylhexyl) phthalate (MEHP)-induced Sertoli cell injury: Probably an indirect action via the regulation of NF?B/FasL circuitry

    SciTech Connect (OSTI)

    Chen, Shiwei [Department of Urology, 174th Hospital of PLA, Fujian 361001 (China)] [Department of Urology, 174th Hospital of PLA, Fujian 361001 (China); Dong, Yushu [Department of Neurosurgery, 463rd Hospital of PLA, Shenyang 110042 (China)] [Department of Neurosurgery, 463rd Hospital of PLA, Shenyang 110042 (China); Xu, Chun; Jiang, Liming; Chen, Yongjie; Jiang, Cheng [Department of Urology, 174th Hospital of PLA, Fujian 361001 (China)] [Department of Urology, 174th Hospital of PLA, Fujian 361001 (China); Hou, Wugang, E-mail: gangwuhou@163.com [Department of Anesthesiology, Xijing Hospital, Fourth Military Medical University, Xi’an 710032 (China)] [Department of Anesthesiology, Xijing Hospital, Fourth Military Medical University, Xi’an 710032 (China); Li, Wei, E-mail: liweipepeyato@163.com [Department of Human Anatomy, Histology and Embryology, Fourth Military Medical University, Xi’an 710032 (China)] [Department of Human Anatomy, Histology and Embryology, Fourth Military Medical University, Xi’an 710032 (China)

    2013-11-01

    Highlights: •MTA1 expression is upregulated in SCs upon MEHP treatment. •Knockdown of MTA1 in SCs impairs the MEHP-induced NF?B signaling activation. •Knockdown of MTA1 inhibits recruitment of NF?B onto FasL promoter in MEHP-treated SCs. -- Abstract: The Fas/FasL signaling pathway, controlled by nuclear factor-?B (NF?B) at the transcriptional level, is critical for triggering germ cell apoptosis in response to mono-(2-ethylhexyl) phthalate (MEHP)-induced Sertoli cell (SC) injury, but the exact regulation mechanism remain unknown. Here, we discovered that expression level of Metastasis associated protein 1 (MTA1), a component of the Mi-2/nucleosome remodeling and deacetylase complex, was upregulated in SCs during the early recovery after MEHP exposure. This expression change was in line with the dynamic changes in germ cell apoptosis in response to MEHP treatment. Furthermore, a knockdown of MTA1 by RNAi in SCs was found to impair the MEHP-induced early activation of NF?B pathway and abolish the recruitment of NF?B onto FasL promoter, which consequently diminished the MEHP-triggered FasL induction. Considering that Fas/FasL is a well characterized apoptosis initiating signaling during SCs injury, our results point to a potential “switch on” effect of MTA1, which may govern the activation of NF?B/FasL cascade in MEHP-insulted SCs. Overall, the MTA1/NF?B/FasL circuit may serve as an important defensive/repairing mechanism to help to control the germ cell quality after SCs injury.

  1. Rosiglitazone attenuates NF-{kappa}B-dependent ICAM-1 and TNF-{alpha} production caused by homocysteine via inhibiting ERK{sub 1/2}/p38MAPK activation

    SciTech Connect (OSTI)

    Bai, Yong-Ping [Department of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha, Hunan 410078 (China); Liu, Yu-Hui [Department of Pharmacology, College of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi 330006 (China); Chen, Jia [Department of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha, Hunan 410078 (China); Song, Tao [Department of Pharmacology, School of Pharmaceutical Sciences, Central South University, Changsha, Hunan 410078 (China); You, Yu [Department of Digestive Medicine, Xiangya Second Hospital, Central South University, Changsha, Hunan 410078 (China); Tang, Zhen-Yan [Department of Urologic Surgery, Xiangya Hospital, Central South University, Changsha, Hunan 410078 (China); Li, Yuan-Jian [Department of Pharmacology, School of Pharmaceutical Sciences, Central South University, Changsha, Hunan 410078 (China); Zhang, Guo-Gang [Department of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha, Hunan 410078 (China)]. E-mail: xyzgg2006@sina.com

    2007-08-17

    Previous studies demonstrated an important interaction between nuclear factor-kappaB (NF-{kappa}B) activation and homocysteine (Hcy)-induced cytokines expression in endothelial cells and vascular smooth muscle cells. However, the underlying mechanism remains illusive. In this study, we investigated the effects of Hcy on NF-{kappa}B-mediated sICAM-1, TNF-{alpha} production and the possible involvement of ERK{sub 1/2}/p38MAPK pathway. The effects of rosiglitazone intervention were also examined. Our results show that Hcy increased the levels of sICAM-1 and TNF-{alpha} in cultured human umbilical vein endothelial cells (HUVECs) in a time- and concentration-dependent manner. This effect was significantly depressed by rosiglitazone and different inhibitors (PDTC, NF-{kappa}B inhibitor; PD98059, MEK inhibitor; SB203580, p38MAPK specific inhibitor; and staurosporine, PKC inhibitor). Next, we investigated the effect of Hcy on ERK{sub 1/2}/p38MAPK pathway and NF-{kappa}B activity in HUVECs. The results show that Hcy activated both ERK{sub 1/2}/p38MAPK pathway and NF-{kappa}B-DNA-binding activity. These effects were markedly inhibited by rosiglitazone as well as other inhibitors (SB203580, PD98059, and PDTC). Further, the pretreatment of staurosporine abrogated ERK{sub 1/2}/p38MAPK phosphorylation, suggesting that Hcy-induced ERK{sub 1/2}/p38MAPK activation is associated with PKC activity. Our results provide evidence that Hcy-induced NF-{kappa}B activation was mediated by activation of ERK{sub 1/2}/p38MAPK pathway involving PKC activity. Rosiglitazone reduces the NF-{kappa}B-mediated sICAM-1 and TNF-{alpha} production induced by Hcy via inhibition of ERK{sub 1/2}/p38MAPK pa0011thw.

  2. VOStat: A Statistical Web Service for Astronomers

    E-Print Network [OSTI]

    Chakraborty, Arnab; Babu, G Jogesh

    2013-01-01

    VOStat is a Web service providing interactive statistical analysis of astronomical tabular datasets. It is integrated into the suite of analysis and visualization tools associated with the international Virtual Observatory (VO) through the SAMP communication system. A user supplies VOStat with a dataset extracted from the VO, or otherwise acquired, and chooses among $\\sim 60$ statistical functions. These include data transformations, plots and summaries, density estimation, one- and two-sample hypothesis tests, global and local regressions, multivariate analysis and clustering, spatial analysis, directional statistics, survival analysis (for censored data like upper limits), and time series analysis. The statistical operations are performed using the public domain {\\bf R} statistical software environment, including a small fraction of its $>4000$ {\\bf CRAN} add-on packages. The purpose of VOStat is to facilitate a wider range of statistical analyses than are commonly used in astronomy, and to promote use of m...

  3. Statistics for characterizing data on the periphery

    SciTech Connect (OSTI)

    Theiler, James P; Hush, Donald R

    2010-01-01

    We introduce a class of statistics for characterizing the periphery of a distribution, and show that these statistics are particularly valuable for problems in target detection. Because so many detection algorithms are rooted in Gaussian statistics, we concentrate on ellipsoidal models of high-dimensional data distributions (that is to say: covariance matrices), but we recommend several alternatives to the sample covariance matrix that more efficiently model the periphery of a distribution, and can more effectively detect anomalous data samples.

  4. Statistical assessment of Monte Carlo distributional tallies

    SciTech Connect (OSTI)

    Kiedrowski, Brian C; Solomon, Clell J

    2010-12-09

    Four tests are developed to assess the statistical reliability of distributional or mesh tallies. To this end, the relative variance density function is developed and its moments are studied using simplified, non-transport models. The statistical tests are performed upon the results of MCNP calculations of three different transport test problems and appear to show that the tests are appropriate indicators of global statistical quality.

  5. Nonextensive statistical effects in nuclear physics problems

    E-Print Network [OSTI]

    G. Kaniadakis; A. Lavagno; M. Lissia; P. Quarati

    1998-12-12

    Recent progresses in statistical mechanics indicate the Tsallis nonextensive thermostatistics as the natural generalization of the standard classical and quantum statistics, when memory effects and long-range forces are not negligible. In this framework, weakly nonextensive statistical deviations can strongly reduce the puzzling discrepancies between experimental data and theoretical previsions for solar neutrinos and for pion transverse-momentum correlations in Pb-Pb high-energy nuclear collisions.

  6. CEAL Statistics 2008-2009: an Overview

    E-Print Network [OSTI]

    Doll, Vickie

    2010-01-01

    stream_size 10836 stream_content_type text/plain stream_name DOLL_CEAL statistics 2008-2009_an overview (JEAL 150).pdf.txt stream_source_info DOLL_CEAL statistics 2008-2009_an overview (JEAL 150).pdf.txt Content-Encoding UTF-8..., study the collection development history, budget trends, collection growth, personnel, and service information. Vickie Fu Doll Chair, CEAL Statistics University of Kansas ...

  7. Statistical Mechanics and Quantum Cosmology

    E-Print Network [OSTI]

    B. L. Hu

    1995-11-29

    Statistical mechanical concepts and processes such as decoherence, correlation, and dissipation can prove to be of basic importance to understanding some fundamental issues of quantum cosmology and theoretical physics such as the choice of initial states, quantum to classical transition and the emergence of time. Here we summarize our effort in 1) constructing a unified theoretical framework using techniques in interacting quantum field theory such as influence functional and coarse-grained effective action to discuss the interplay of noise, fluctuation, dissipation and decoherence; and 2) illustrating how these concepts when applied to quantum cosmology can alter the conventional views on some basic issues. Two questions we address are 1) the validity of minisuperspace truncation, which is usually assumed without proof in most discussions, and 2) the relevance of specific initial conditions, which is the prevailing view of the past decade. We also mention how some current ideas in chaotic dynamics, dissipative collective dynamics and complexity can alter our view of the quantum nature of the universe.

  8. Statistics for Industry Groups and Industries, 2003

    SciTech Connect (OSTI)

    2009-01-18

    Statistics for the U.S. Department of Commerce including types of manufacturing, employees, and products as outlined in the Annual Survey of Manufacturers (ASM).

  9. Statistical methods for nuclear material management

    SciTech Connect (OSTI)

    Bowen W.M.; Bennett, C.A.

    1988-12-01

    This book is intended as a reference manual of statistical methodology for nuclear material management practitioners. It describes statistical methods currently or potentially important in nuclear material management, explains the choice of methods for specific applications, and provides examples of practical applications to nuclear material management problems. Together with the accompanying training manual, which contains fully worked out problems keyed to each chapter, this book can also be used as a textbook for courses in statistical methods for nuclear material management. It should provide increased understanding and guidance to help improve the application of statistical methods to nuclear material management problems.

  10. Accuracy and reliability of China's energy statistics

    E-Print Network [OSTI]

    Sinton, Jonathan E.

    2001-01-01

    China’s Energy Statistics Mtce Primary Consumption Coal Primary Consumption Total Energy Primary Production Primary Production Natural Gas Oil Primary Consumption

  11. Moore honored with American Statistical Association award

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    impact. Moore is a Fellow of the Royal Statistical Society. Her awards include Certified Six Sigma Master Black Belt, Laboratory Distinguished Performance Team Award, and a...

  12. PHYSICS 775 Statistical Physics Lecturer: Maarten Golterman

    E-Print Network [OSTI]

    Golterman, Maarten

    and P. D. Beale, Statistical Mechanics, third edition only, Academic Press (Elsevier). Prerequisites to contact the instructor. The Disability Programs and Resource Center (DPRC) is available to facilitate

  13. Using a calculator to do statistics

    E-Print Network [OSTI]

    Dave

    2012-03-25

    Statistics on a Scientific Calculator. NOTE: Some of these may not be regular keys on your calculator and may appear in a different color above another key.

  14. Anti-neuroinflammatory efficacy of the aldose reductase inhibitor FMHM via phospholipase C/protein kinase C-dependent NF-?B and MAPK pathways

    SciTech Connect (OSTI)

    Zeng, Ke-Wu [State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191 (China); Li, Jun [Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029 (China); Dong, Xin; Wang, Ying-Hong; Ma, Zhi-Zhong; Jiang, Yong; Jin, Hong-Wei [State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191 (China); Tu, Peng-Fei, E-mail: pengfeitu@vip.163.com [State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191 (China); Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029 (China)

    2013-11-15

    Aldose reductase (AR) has a key role in several inflammatory diseases: diabetes, cancer and cardiovascular diseases. Therefore, AR inhibition seems to be a useful strategy for anti-inflammation therapy. In the central nervous system (CNS), microglial over-activation is considered to be a central event in neuroinflammation. However, the effects of AR inhibition in CNS inflammation and its underlying mechanism of action remain unknown. In the present study, we found that FMHM (a naturally derived AR inhibitor from the roots of Polygala tricornis Gagnep.) showed potent anti-neuroinflammatory effects in vivo and in vitro by inhibiting microglial activation and expression of inflammatory mediators. Mechanistic studies showed that FMHM suppressed the activity of AR-dependent phospholipase C/protein kinase C signaling, which further resulted in downstream inactivation of the I?B kinase/I?B/nuclear factor-kappa B (NF-?B) inflammatory pathway. Therefore, AR inhibition-dependent NF-?B inactivation negatively regulated the transcription and expression of various inflammatory genes. AR inhibition by FMHM exerted neuroprotective effects in lipopolysaccharide-induced neuron–microglia co-cultures. These findings suggested that AR is a potential target for neuroinflammation inhibition and that FMHM could be an effective agent for treating or preventing neuroinflammatory diseases. - Highlights: • FMHM is a natural-derived aldose reductase (AR) inhibitor. • FMHM inhibits various neuroinflammatory mediator productions in vitro and in vivo. • FMHM inhibits neuroinflammation via aldose reductase/PLC/PKC-dependent NF-?B pathway. • FMHM inhibits neuroinflammation via aldose reductase/PLC/PKC-dependent MAPK pathway. • FMHM protects neurons against inflammatory injury in microglia-neuron co-cultures.

  15. Mangiferin exerts hepatoprotective activity against D-galactosamine induced acute toxicity and oxidative/nitrosative stress via Nrf2–NF?B pathways

    SciTech Connect (OSTI)

    Das, Joydeep; Ghosh, Jyotirmoy; Roy, Anandita; Sil, Parames C.

    2012-04-01

    Mangiferin, a xanthone glucoside, is well known to exhibit antioxidant, antiviral, antitumor, anti-inflammatory and gene-regulatory effects. In the present study, we isolated mangiferin from the bark of Mangifera indica and assessed its beneficial role in galactosamine (GAL) induced hepatic pathophysiology. GAL (400 mg/kg body weight) exposed hepatotoxic rats showed elevation in the activities of serum ALP, ALT, levels of triglycerides, total cholesterol, lipid-peroxidation and reduction in the levels of serum total proteins, albumin and cellular GSH. Besides, GAL exposure (5 mM) in hepatocytes induced apoptosis and necrosis, increased ROS and NO production. Signal transduction studies showed that GAL exposure significantly increased the nuclear translocation of NF?B and elevated iNOS protein expression. The same exposure also elevated TNF-?, IFN-?, IL-1?, IL-6, IL-12, IL-18 and decreased IL-10 mRNA expressions. Furthermore, GAL also decreased the protein expression of Nrf2, NADPH:quinine oxidoreductase-1, heme oxygenase-1 and GST?. However, mangiferin administration in GAL intoxicated rats or coincubation of hepatocytes with mangiferin significantly altered all these GAL-induced adverse effects. In conclusion, the hepatoprotective role of mangiferin was due to induction of antioxidant defense via the Nrf2 pathway and reduction of inflammation via NF?B inhibition. Highlights: ?Galactosamine induces hepatocytes death via oxidative and nitrosative stress. ?Mangiferin exerts hepatoprotective effect/antioxidant defense via Nrf2 pathway. ?Mangiferin exerts anti-inflammatory responses by inhibiting NF-?B. ?Mangiferin suppresses galactosamine-induced repression of IL-10 mRNA.

  16. Bridging the Gap Between Tools for Learning and for Doing Statistics

    E-Print Network [OSTI]

    McNamara, Amelia Ahlers

    2015-01-01

    State of statistics knowledge . . . . . . .learning statistics . . . . . . . . . . . . . . . . The gaplearning and for doing statistics . . History of tools for

  17. November 2011 MSc and Diploma in Applied Statistics 2011

    E-Print Network [OSTI]

    Goldschmidt, Christina

    ;2 Statistical Methods 28 17 3.0 3 Statistical Theory 27 12 5.0 4 Statistical Theory 27 8 5.5 5 R Programming 28November 2011 MSc and Diploma in Applied Statistics 2011: Examiners' Report Part I A STATISTICS (1) Numbers and percentages in each category MSc in Applied Statistics Category Number Percentage 2010

  18. Statistics beyond Physics -Misused in Public ?

    E-Print Network [OSTI]

    Kobe, Sigismund

    and oranges (vergleiche Äpfel mit Birnen) #12;2.1 Local criterium Example: 1 murder in Pirna statistically smeared over Germany PIR Result: ,,0.002 murder" attributed to Saarbrücken, 0.05 to Berlin, .... 0;3. Confidence region ... of data points Example: from PKS (German Police Crime Statistics): The number of murder

  19. GIS, SPATIAL STATISTICAL GRAPHICS, AND FOREST HEALTH.

    E-Print Network [OSTI]

    Symanzik, Jürgen

    1 GIS, SPATIAL STATISTICAL GRAPHICS, AND FOREST HEALTH. James J. Majure, Noel Cressie, Dianne Cook, and Jürgen Symanzik ABSTRACT This paper discusses the use of a geographic information systems (GIS), Arcview, into a geographic information system (GIS), Arcview 2.1 (ESRI 1995), and its use in the statistical analysis of spa

  20. DEPARTMENT OF STATISTICS North Carolina State University

    E-Print Network [OSTI]

    Zhang, Hao "Helen"

    DEPARTMENT OF STATISTICS North Carolina State University 2501 Founders Drive, Campus Box 8203 for Nonparametric Regression in Exponential Families Hao Zhang Department of Statistics, North Carolina State Zhang and Yi Lin North Carolina State University and University of Wisconsin at Madison Abstract: We

  1. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    - dimensional data. In this context, graphical models can act as a tool for regularization and have proven to be excellent tools for the analysis of high dimensional data. Graphi- cal models are statistical models where procedures for graphical models have recently received much attention in the statistics literature. The hyper

  2. Statistical Seismology DAVID VERE-JONES,1

    E-Print Network [OSTI]

    Ben-Zion, Yehuda

    models without statistics, and statistics-based models without physics. This volume, which is based such broad insights into tractable explicit models, that can be fitted to a specific data set and used observations demand matching techniques of modeling and data anal

  3. Statistics W4240: Data Mining Columbia University

    E-Print Network [OSTI]

    Columbia University

    Statistics W4240: Data Mining Columbia University Spring, 2014 Version: January 30, 2014 Massive data collection and storage capacities have led to new statistical questions: · Amazon collects and collects user click-through data on those stories. How should it organize the stories based on the click

  4. Statistical data mining Finn Arup Nielsen

    E-Print Network [OSTI]

    Nielsen, Finn Årup

    Statistical data mining Finn °Arup Nielsen Informatics and Mathematical Modelling Technical University of Denmark February 3, 2004 #12;Introduction · "Statistical data mining". · The goal is "knowledge databases (PubMed, MeSH, fMRIDC, SenseLab) Finn °Arup Nielsen 2 February 3, 2004 #12;Mining for novelty

  5. Department of Mathematics MAL 522 (Statistical Inference)

    E-Print Network [OSTI]

    Dharmaraja, S.

    location parameter family the sample variance is ancillary. 9. Using Basu's theorem establish that sample parameter . Show that (Y1, Y2, . . . , Yn-1) where Yi = X(n) - X(i), i = 1, 2, . . . , n - 1 is ancillary or not the ancillary statistics (Y1, Y2, . . . , Yn-1) is independent of the minimal sufficient statistics of . 12

  6. Conditional statistical inference and quantification of relevance

    E-Print Network [OSTI]

    Sundberg, Rolf

    a quantification of the concept of relevance for conditional in- ference. Conditioning on an ancillary statistic makes inference more relevant in this sense, provided that the ancillary is a precision index. Not all ancillary statistics satisfy this demand. We discuss the problem of choice between alternative ancillary

  7. Multivariate Statistical Tests for Comparing Classification Algorithms

    E-Print Network [OSTI]

    Alpaydýn, Ethem

    Multivariate Statistical Tests for Comparing Classification Algorithms Olcay Taner Yildiz1 , ¨Ozlem these in a single number, we propose to collect multivariate statistics and use multivariate tests on them rate (tpr) and false positive rate (fpr) and a multivariate test can also use such two values instead

  8. STATISTICAL STUDIES OF FILAMENT DISAPPEARANCES AND CMES

    E-Print Network [OSTI]

    STATISTICAL STUDIES OF FILAMENT DISAPPEARANCES AND CMES G. Yang and H. Wang 1 1Big Bear Solar Observatory, 40386 North Shore Lane, Big Bear City, CA 92314, USA ABSTRACT A statistical study of filament full disk images observed between January 1997 and June 1999 is searched for filament and prominence

  9. Towards a Statistically Semantic Web Gerhard Weikum

    E-Print Network [OSTI]

    Waldmann, Uwe

    1/44 Towards a Statistically Semantic Web Gerhard Weikum weikum@mpi-sb.mpg.de http://www.mpi-sb.mpg: ,,There is no semantic anything in CS." Alon Halevy: ,,Structure + Statistics = Semantics" Tim Berners of one`s ignorance." 4/44 #12;A Few Challenging Queries (on Web / Deep Web / Intranet / Personal Info

  10. Computational Aspects in Statistical Signal Processing

    E-Print Network [OSTI]

    Kundu, Debasis

    14 Computational Aspects in Statistical Signal Processing D. Kundu 14.1 Introduction Signal such as communi- cations, radio location of objects, seismic signal processing and computer assisted medical diagnosis. Statistical signal processing is also used in many physical science applications

  11. Factored Language Models for Statistical Machine Translation

    E-Print Network [OSTI]

    Koehn, Philipp

    Factored Language Models for Statistical Machine Translation Amittai E. Axelrod TH E U N I V E R . . . . . . . . . . . . . . . . . . . . . 10 2.4.3 Log-Linear, Phrase-Based Translation Models . . . . . . . . . 11 3 Statistical Language S ITY OF E D I N B U R G H Master of Science by Research Institute for Communicating and Collaborative

  12. Introduction to Statistical Linear Models Spring 2005

    E-Print Network [OSTI]

    of multivariate data and in the language of matrices and vectors. Broad introduction to MATLAB/Octave, R (SSyllabus Introduction to Statistical Linear Models 960:577:01 Spring 2005 Instructor: Farid Statistical Analysis" Fifth edition, Prentice Hall, 2002. Other sources may be required and will be posted

  13. : ( Statistical computing) : (Pi-Wen Tsai)

    E-Print Network [OSTI]

    Tsai, Pi-Wen

    computing "methods", with an emphasis on using the R language (http://www.r-project.org/) via an examples-Hastings algorithm, Gibbs sampler. 9. EM algorithm , (a) Rizzo, M. L. (2007), Statistical computing with R : ( Statistical computing) : (Pi-Wen Tsai) E-mail : pwtsai@math.ntnu.edu.tw or pwtsai

  14. Scalable Statistical Bug Isolation Computer Sciences Department

    E-Print Network [OSTI]

    Aiken, Alex

    algorithm that isolates bugs in programs containing multiple undiagnosed bugs. Earlier statistical Descriptors D.2.4 [Software Engineer- ing]: Software/Program Verification--statistical methods; D.2 with a program point may or may not be tested each time the program point is reached). A feedback report R

  15. Fractal Statistics and Quantum Black Hole Entropy

    E-Print Network [OSTI]

    Wellington da Cruz

    2000-11-18

    Simple considerations about the fractal characteristic of the quantum-mechanical path give us the opportunity to derive the quantum black hole entropy in connection with the concept of fractal statistics. We show the geometrical origin of the numerical factor of four of the quantum black hole entropy expression and the statistics weight appears as a counting of the quanta of geometry.

  16. Degenerate U-and V -statistics under ergodicity: Asymptotics, bootstrap and applications in statistics

    E-Print Network [OSTI]

    Degenerate U- and V -statistics under ergodicity: Asymptotics, bootstrap and applications in statistics Anne Leucht Universit¨at Hamburg Fachbereich Mathematik, SPST Bundesstraße 55 D-20146 Hamburg.neumann@uni-jena.de Abstract We derive the asymptotic distributions of degenerate U- and V -statistics of stationary

  17. Graduate Programs in Mathematics, Statistics, and Physics The Department of Mathematics, Statistics, and Physics at

    E-Print Network [OSTI]

    Graduate Programs in Mathematics, Statistics, and Physics The Department of Mathematics, Statistics, and Physics at Wichita State University offers courses leading to the Master of Science (MS) degree in the doctoral program in applied mathematics are applied mathematics, statistics, and applied mathematics-physics

  18. Principles of Statistical Inference Department of Statistics, University of Toronto, Canada

    E-Print Network [OSTI]

    Reid, Nancy

    and D. R. Cox Nuffield College, Oxford, UK Abstract Statistical theory aims to provide a foundationPrinciples of Statistical Inference N. Reid Department of Statistics, University of Toronto, Canada, and a common language for summarizing results; ideally the foundations and common language ensure

  19. Topology for statistical modeling of petascale data.

    SciTech Connect (OSTI)

    Pascucci, Valerio (University of Utah, Salt Lake City, UT); Mascarenhas, Ajith Arthur; Rusek, Korben (Texas A& M University, College Station, TX); Bennett, Janine Camille; Levine, Joshua (University of Utah, Salt Lake City, UT); Pebay, Philippe Pierre; Gyulassy, Attila (University of Utah, Salt Lake City, UT); Thompson, David C.; Rojas, Joseph Maurice (Texas A& M University, College Station, TX)

    2011-07-01

    This document presents current technical progress and dissemination of results for the Mathematics for Analysis of Petascale Data (MAPD) project titled 'Topology for Statistical Modeling of Petascale Data', funded by the Office of Science Advanced Scientific Computing Research (ASCR) Applied Math program. Many commonly used algorithms for mathematical analysis do not scale well enough to accommodate the size or complexity of petascale data produced by computational simulations. The primary goal of this project is thus to develop new mathematical tools that address both the petascale size and uncertain nature of current data. At a high level, our approach is based on the complementary techniques of combinatorial topology and statistical modeling. In particular, we use combinatorial topology to filter out spurious data that would otherwise skew statistical modeling techniques, and we employ advanced algorithms from algebraic statistics to efficiently find globally optimal fits to statistical models. This document summarizes the technical advances we have made to date that were made possible in whole or in part by MAPD funding. These technical contributions can be divided loosely into three categories: (1) advances in the field of combinatorial topology, (2) advances in statistical modeling, and (3) new integrated topological and statistical methods.

  20. NF_Eder_2013

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration wouldMass map shines light on771/6/14 Contact: Janet Lambert4 FLCNETL-ORD4NEVIS-NEWS MEDIAmail3

  1. TGF-{beta}1 increases invasiveness of SW1990 cells through Rac1/ROS/NF-{kappa}B/IL-6/MMP-2

    SciTech Connect (OSTI)

    Binker, Marcelo G.; CBRHC Research Center, Buenos Aires ; Binker-Cosen, Andres A.; Gaisano, Herbert Y.; Cosen, Rodica H. de; Cosen-Binker, Laura I.

    2011-02-04

    Research highlights: {yields} Rac1 mediates TGF-{beta}1-induced SW1990 invasion through MMP-2 secretion and activation. {yields} NADPH-generated ROS act downstream of Rac1 in TGF-{beta}1-challenged SW1990 cells. {yields} TGF-{beta}1-stimulated ROS activate NF-{kappa}B in SW1990 cells. {yields} NF{kappa}B-induced IL-6 release is required for secretion and activation of MMP-2 in SW1990 cells. -- Abstract: Human pancreatic cancer invasion and metastasis have been found to correlate with increased levels of active matrix metalloproteinase 2 (MMP-2). The multifunctional cytokine transforming growth factor beta 1 (TGF-{beta}1) has been shown to increase both secretion of MMP-2 and invasion by several pancreatic cancer cell types. In the present study, we investigated the signaling pathway involved in TGF-{beta}1-promoted MMP-2 secretion and invasion by human pancreatic cancer cells SW1990. Using specific inhibitors, we found that stimulation of these tumor cells with TGF-{beta}1 induced secretion and activation of the collagenase MMP-2, which was required for TGF-{beta}1-stimulated invasion. Our results also indicate that signaling events involved in TGF-{beta}1-enhanced SW1990 invasiveness comprehend activation of Rac1 followed by generation of reactive oxygen species through nicotinamide adenine dinucleotide phosphate-oxidase, activation of nuclear factor-kappa beta, release of interleukin-6, and secretion and activation of MMP-2.

  2. Quantum Statistical Processes in the Early Universe

    E-Print Network [OSTI]

    B. L. Hu

    1993-02-22

    We show how the concept of quantum open system and the methods in non-equilibrium statistical mechanics can be usefully applied to studies of quantum statistical processes in the early universe. We first sketch how noise, fluctuation, dissipation and decoherence processes arise in a wide range of cosmological problems. We then focus on the origin and nature of noise in quantum fields and spacetime dynamics. We introduce the concept of geometrodynamic noise and suggest a statistical mechanical definition of gravitational entropy. We end with a brief discussion of the theoretical appropriateness to view the physical universe as an open system.

  3. Time as a parameter of statistical ensemble

    E-Print Network [OSTI]

    Sergei Viznyuk

    2011-11-26

    The notion of time is derived as a parameter of statistical ensemble representing the underlying system. Varying population numbers of microstates in statistical ensemble result in different expectation values corresponding to different times. We show a single parameter which equates to the notion of time is logarithm of the total number of microstates in statistical ensemble. We discuss the implications of proposed model for some topics of modern physics: Poincar\\'e recurrence theorem vs. Second Law of Thermodynamics, matter vs. anti-matter asymmetry of the universe, expansion of the universe, Big Bang.

  4. Spin - or, actually: Spin and Quantum Statistics

    E-Print Network [OSTI]

    Juerg Froehlich

    2008-02-29

    The history of the discovery of electron spin and the Pauli principle and the mathematics of spin and quantum statistics are reviewed. Pauli's theory of the spinning electron and some of its many applications in mathematics and physics are considered in more detail. The role of the fact that the tree-level gyromagnetic factor of the electron has the value g = 2 in an analysis of stability (and instability) of matter in arbitrary external magnetic fields is highlighted. Radiative corrections and precision measurements of g are reviewed. The general connection between spin and statistics, the CPT theorem and the theory of braid statistics are described.

  5. Interdisciplinary Mathematics/Statistics Actuarial Science Sample ...

    E-Print Network [OSTI]

    Interdisciplinary Mathematics/Statistics Actuarial Science Sample Plan 2 . 1 MA 161 (4-5) MA/S T 170 ENGL 101 Lab Science Language or 165, 173, 181, 271 ...

  6. Statistical analysis of correlated fossil fuel securities

    E-Print Network [OSTI]

    Li, Derek Z

    2011-01-01

    Forecasting the future prices or returns of a security is extraordinarily difficult if not impossible. However, statistical analysis of a basket of highly correlated securities offering a cross-sectional representation of ...

  7. 15.075 Applied Statistics, Spring 2003

    E-Print Network [OSTI]

    Newton, Elizabeth

    This course is an introduction to applied statistics and data analysis. Topics include collecting and exploring data, basic inference, simple and multiple linear regression, analysis of variance, nonparametric methods, and ...

  8. Statistical criteria for characterizing irradiance time series.

    SciTech Connect (OSTI)

    Stein, Joshua S.; Ellis, Abraham; Hansen, Clifford W.

    2010-10-01

    We propose and examine several statistical criteria for characterizing time series of solar irradiance. Time series of irradiance are used in analyses that seek to quantify the performance of photovoltaic (PV) power systems over time. Time series of irradiance are either measured or are simulated using models. Simulations of irradiance are often calibrated to or generated from statistics for observed irradiance and simulations are validated by comparing the simulation output to the observed irradiance. Criteria used in this comparison should derive from the context of the analyses in which the simulated irradiance is to be used. We examine three statistics that characterize time series and their use as criteria for comparing time series. We demonstrate these statistics using observed irradiance data recorded in August 2007 in Las Vegas, Nevada, and in June 2009 in Albuquerque, New Mexico.

  9. Statistical Sciences Group, Los Alamos National Laboratory,

    E-Print Network [OSTI]

    Wolfe, Patrick J.

    Luke Bornn CCS-6, Statistical Sciences Group, Los Alamos National Laboratory, MS F600, Los Alamos Institute, Los Alamos National Laboratory, MS T006, Los Alamos, NM 87545 Structural Health Monitoring

  10. Generalized binomial distribution in photon statistics

    E-Print Network [OSTI]

    Aleksey V. Ilyin

    2015-05-28

    The photon-number distribution between two parts of a given volume is found for an arbitrary photon statistics. This problem is related to the interaction of a light beam with a macroscopic device, for example a diaphragm, that separates the photon flux into two parts with known probabilities. To solve this problem, a Generalized Binomial Distribution (GBD) is derived that is applicable to an arbitrary photon statistics satisfying probability convolution equations. It is shown that if photons obey Poisson statistics then the GBD is reduced to the ordinary binomial distribution, whereas in the case of Bose-Einstein statistics the GBD is reduced to the Polya distribution. In this case, the photon spatial distribution depends on the phase-space volume occupied by the photons. This result involves a photon bunching effect, or collective behavior of photons that sharply differs from the behavior of classical particles. It is shown that the photon bunching effect looks similar to the quantum interference effect.

  11. Statistical mechanics of a cat's cradle

    E-Print Network [OSTI]

    Shen, Tongye; Wolynes, Peter G

    2006-01-01

    cells. In our view, cell mechanics remains at an early stagefor physics Statistical mechanics of a cat’s cradle Tongyemodel [2, 3] of cell mechanics [7], but here we limit

  12. Mathematics and Statistics Handbook College of Engineering

    E-Print Network [OSTI]

    Hickman, Mark

    , Chemistry, Physics, Geography, Geology, Biology, Economics and Finance, Philosophy and Engineering. We host of different jobs that require mathematics or statistics and demand for graduates is ever expanding. We live

  13. I/O Statistics Last 30 Days

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Last 30 Days These plots show the daily statistics for the last 30 days for the storage systems at NERSC in terms of the amount of data transferred and the number of files...

  14. Introduction to Statistical Issues in Particle Physics

    E-Print Network [OSTI]

    Roger Barlow

    2003-11-20

    An account is given of the methods of working of Experimental High Energy Particle Physics, from the viewpoint of statisticians and others unfamiliar with the field. Current statistical problems, techniques, and hot topics are introduced and discussed.

  15. Multivariate Statistical Analysis of Assembly Tolerance Specifications

    E-Print Network [OSTI]

    i Multivariate Statistical Analysis of Assembly Tolerance Specifications A Thesis Presented ..........................................................................................................12 2.6.1 Multivariate Normal Distributions.8.3 Combined Assembly Specification Quality...............................................22 2.9 Multivariate

  16. Understanding Manufacturing Energy Use Through Statistical Analysis 

    E-Print Network [OSTI]

    Kissock, J. K.; Seryak, J.

    2004-01-01

    Energy in manufacturing facilities is used for direct production of goods, space conditioning, and general facility support such as lighting. This paper presents a methodology for statistically analyzing plant energy use in terms of these major end...

  17. Model Risk in Finance Department of Statistics

    E-Print Network [OSTI]

    Stine, Robert A.

    worth taking Statistical issues Multiplicity Transformations to obtain "independence" Orthogonality Year Valueof$100Investment Case-Shiller Housing Total Stock Market 3 #12;Wharton default Correlation risk Regulatory risk Reputation risk Operational risk Systemic risk, market risk

  18. APS Operational Statistics for FY 2011

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    FY 2011 Bar Chart of Downtime by System HTML or PDF FY 2011 Bar Chart of Faults by System HTML or PDF Run Statistics by WeekHTML or PDF Studies BreakdownSummary(PDF) Details(PDF)...

  19. Twisted Statistics in kappa-Minkowski Spacetime

    E-Print Network [OSTI]

    T. R. Govindarajan; Kumar S. Gupta; E. Harikumar; S. Meljanac; D. Meljanac

    2008-03-10

    We consider the issue of statistics for identical particles or fields in kappa-deformed spaces, where the system admits a symmetry group G. We obtain the twisted flip operator compatible with the action of the symmetry group, which is relevant for describing particle statistics in presence of the noncommutativity. It is shown that for a special class of realizations, the twisted flip operator is independent of the ordering prescription.

  20. Statistical Mechanics of Two-dimensional Foams

    E-Print Network [OSTI]

    Marc Durand

    2010-09-07

    The methods of statistical mechanics are applied to two-dimensional foams under macroscopic agitation. A new variable -- the total cell curvature -- is introduced, which plays the role of energy in conventional statistical thermodynamics. The probability distribution of the number of sides for a cell of given area is derived. This expression allows to correlate the distribution of sides ("topological disorder") to the distribution of sizes ("geometrical disorder") in a foam. The model predictions agree well with available experimental data.

  1. FISHERY STATISTICS I OF THE UNITED STATESmmmMM

    E-Print Network [OSTI]

    ^^ FISHERY STATISTICS I OF THE UNITED STATESmmmMM 'f^ gjIP^Ws^WI'l STATISTICAL DIGEST NO. 25 Fish Statistical Digest 25 FISHERY STATISTICS OF THE UNITED STATES 1949 BY A. W. ANDERSON and C. E. PETERSON UNITED. Government Printing Office, Washington 25, D. C. - - - Price $1.25 (paper) #12;Fishery Statistics

  2. On Characterization of Two-Sample U-Statistics

    E-Print Network [OSTI]

    Schechtman, Gideon

    On Characterization of Two-Sample U-Statistics E. Schechtman #3; Department of Industrial@wisdom.weizmann.ac.il Abstract A veri#12;able condition for a symmetric statistic to be a two-sample U-statistic is given. As an illustration, we characterize which linear rank statistics with two-sample regression constants are U-statistics

  3. STATISTICS MAJOR REQUIREMENTS: ADVISEMENT FORM BACHELOR OF SCIENCE DEGREE

    E-Print Network [OSTI]

    Suri, Manil

    STATISTICS MAJOR REQUIREMENTS: ADVISEMENT FORM BACHELOR OF SCIENCE DEGREE APPLIED STATISTICS TRACK STAT 350 Statistics with Applications in the Biological Sciences OR STAT 351 Applied Statistics for Business and Economics OR STAT 355 Introduction to Probability and Statistics for Scientists and Engineers

  4. Estimating Wireless Network Properties with Spatial Statistics and Models

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Estimating Wireless Network Properties with Spatial Statistics and Models Janne Riihij statistics and models for different estimation problems related to wireless networks. We focus specifically wireless networks. We provide a concise survey of existing techniques from the spatial statistics

  5. OpenIntro Statistics: an Open-source Textbook

    E-Print Network [OSTI]

    Cetinkaya-Rundel, Mine; Diez, David M; Barr, Christopher D

    2013-01-01

    OpenIntro Statistics: an open-source textbook 1.0to teaching introductory statistics. Section 2 also touchesIntroductory courses in statistics, the type that require no

  6. Local asymptotic normality in quantum statistics

    E-Print Network [OSTI]

    Madalin Guta; Anna Jencova

    2007-05-24

    The theory of local asymptotic normality for quantum statistical experiments is developed in the spirit of the classical result from mathematical statistics due to Le Cam. Roughly speaking, local asymptotic normality means that the family varphi_{\\theta_{0}+ u/\\sqrt{n}}^{n} consisting of joint states of n identically prepared quantum systems approaches in a statistical sense a family of Gaussian state phi_{u} of an algebra of canonical commutation relations. The convergence holds for all "local parameters" u\\in R^{m} such that theta=theta_{0}+ u/sqrt{n} parametrizes a neighborhood of a fixed point theta_{0}\\in Theta\\subset R^{m}. In order to prove the result we define weak and strong convergence of quantum statistical experiments which extend to the asymptotic framework the notion of quantum sufficiency introduces by Petz. Along the way we introduce the concept of canonical state of a statistical experiment, and investigate the relation between the two notions of convergence. For reader's convenience and completeness we review the relevant results of the classical as well as the quantum theory.

  7. Fact #602: December 21, 2009 Freight Statistics by Mode, 2007...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    2: December 21, 2009 Freight Statistics by Mode, 2007 Commodity Flow Survey Fact 602: December 21, 2009 Freight Statistics by Mode, 2007 Commodity Flow Survey Results from the...

  8. Statistical Design, Analysis and Graphics for the Guadalupe

    E-Print Network [OSTI]

    Statistical Design, Analysis and Graphics for the Guadalupe River Assessment Technical Memoranda Science Center (2013). Statistical Design, Analysis and Graphics for the Guadalupe River Assessment...................................................................................................... 7 Study Design

  9. Stochastically Lighting Up Galaxies: Statistical Implications of Stellar Clustering

    E-Print Network [OSTI]

    da Silva, Robert Louis

    2014-01-01

    SANTA CRUZ STOCHASTICALLY LIGHTING UP GALAXIES: STATISTICAL2 SLUG - Stochastically Lighting Up Galaxies: Methods andx Abstract Stochastically Lighting Up Galaxies: Statistical

  10. Statistical surrogate models for prediction of high-consequence...

    Office of Scientific and Technical Information (OSTI)

    Technical Report: Statistical surrogate models for prediction of high-consequence climate change. Citation Details In-Document Search Title: Statistical surrogate models for...

  11. Statistical Surrogate Models for Estimating Probability of High...

    Office of Scientific and Technical Information (OSTI)

    Statistical Surrogate Models for Estimating Probability of High-Consequence Climate Change. Citation Details In-Document Search Title: Statistical Surrogate Models for Estimating...

  12. Learning Statistics Using Motivational Videos, Real Data and Free Software

    E-Print Network [OSTI]

    Harraway, John A

    2012-01-01

    S. (2010) Statistical software for teaching: relevant,2005) Fathom Dynamic Data Software (Version 2) Emeryville,to R. Journal of Statistical Software. 14: (9). URL http://

  13. Independence of some polynomial statistics and of the sample mean

    E-Print Network [OSTI]

    2005-01-07

    problems of mathematical statistics consists of determining the functions F(t) for which ... statistics is linear, the general method of solving such problems is that of

  14. Environment/Health/Safety (EHS): Monthly Accident Statistics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Personal Protective Equipment (PPE) Injury Review & Analysis Worker Safety and Health Program: PUB-3851 Monthly Accident Statistics Latest Accident Statistics Accident...

  15. 4-Hydroxyestradiol induces oxidative stress and apoptosis in human mammary epithelial cells: possible protection by NF-{kappa}B and ERK/MAPK

    SciTech Connect (OSTI)

    Chen Zhihua [National Research Laboratory of Molecular Carcinogenesis and Chemoprevention, College of Pharmacy, Seoul National University, Shinlim-dong, Kwanak-ku, Seoul 151-742 (Korea, Republic of); Na, Hye-Kyung [National Research Laboratory of Molecular Carcinogenesis and Chemoprevention, College of Pharmacy, Seoul National University, Shinlim-dong, Kwanak-ku, Seoul 151-742 (Korea, Republic of); Hurh, Yeon-Jin [National Research Laboratory of Molecular Carcinogenesis and Chemoprevention, College of Pharmacy, Seoul National University, Shinlim-dong, Kwanak-ku, Seoul 151-742 (Korea, Republic of); Surh, Young-Joon [National Research Laboratory of Molecular Carcinogenesis and Chemoprevention, College of Pharmacy, Seoul National University, Shinlim-dong, Kwanak-ku, Seoul 151-742 (Korea, Republic of)]. E-mail: surh@plaza.snu.ac.kr

    2005-10-01

    Catechol estrogens, the hydroxylated metabolites of 17{beta}-estradiol (E{sub 2}), have been considered to be implicated in estrogen-induced carcinogenesis. 4-Hydroxyestradiol (4-OHE{sub 2}), an oxidized metabolite of E{sub 2} formed preferentially by cytochrome P450 1B1, reacts with DNA to form depurinating adducts thereby exerting genotoxicity and carcinogenicity. 4-OHE{sub 2} undergoes 2-electron oxidation to quinone via semiquinone, and during this process, reactive oxygen species (ROS) can be generated to cause DNA damage and cell death. In the present study, 4-OHE{sub 2} was found to elicit cytotoxicity in cultured human mammary epithelial (MCF-10A) cells, which was blocked by the antioxidant trolox. MCF-10A cells treated with 4-OHE{sub 2} exhibited increased intracellular ROS accumulation and 8-oxo-7,8-dihydroxy-2'-deoxyguanosine formation, and underwent apoptosis as determined by poly(ADP-ribose)polymerase cleavage and disruption of mitochondrial transmembrane potential. The redox-sensitive transcription factor nuclear factor {kappa}B (NF-{kappa}B) was transiently activated by 4-OHE{sub 2} treatment. Cotreatment of MCF-10A cells with the NF-{kappa}B inhibitor, L-1-tosylamido-2-phenylethyl chloromethyl ketone, exacerbated 4-OHE{sub 2}-induced cell death. 4-OHE{sub 2} also caused transient activation of extracellular signal-regulated protein kinases (ERK) involved in transmitting cell survival or death signals. A pharmacological inhibitor of ERK aggravated the 4-OHE{sub 2}-induced cytotoxicity, supporting the pivotal role of ERK in protecting against catechol estrogen-induced oxidative cell death.

  16. Semi-Poisson statistics in quantum chaos

    E-Print Network [OSTI]

    Antonio M. Garcia-Garcia; Jiao Wang

    2006-05-01

    We investigate the quantum properties of a non-random Hamiltonian with a step-like singularity. It is shown that the eigenfunctions are multifractals and, in a certain range of parameters, the level statistics is described exactly by Semi-Poisson statistics (SP) typical of pseudo-integrable systems. It is also shown that our results are universal; namely, they depend exclusively on the presence of the step-like singularity and are not modified by smooth perturbations of the potential or the addition of a magnetic flux. Although the quantum properties of our system are similar to those of a disordered conductor at the Anderson transition, we report important quantitative differences in both the level statistics and the multifractal dimensions controlling the transition. Finally the study of quantum transport properties suggests that the classical singularity induces quantum anomalous diffusion. We discuss how these findings may be experimentally corroborated by using ultra cold atoms techniques.

  17. Spin-Statistics Violations in Superstring Theory

    E-Print Network [OSTI]

    Mark G. Jackson

    2008-12-30

    I describe how superstring theory may violate spin-statistics in an experimentally observable manner. Reviewing the basics of superstring interactions and how to utilize these to produce a statistical phase, I then apply these ideas to two specific examples. The first is the case of heterotic worldsheet linkings, whereby one small closed string momentarily enlarges sufficiently to pass over another, producing such a statistical phase. The second is the braneworld model with noncommutative geometry, whereby matter composed of open strings may couple to a background in which spacetime coordinates do not commute, modifying the field (anti)commutator algebra. I conclude with ways to sharpen and experimentally test these exciting avenues to possibly verify superstring theory.

  18. A Google Scholar gadget for calculating author citations and other statistical information regarding publications. more... Statistics

    E-Print Network [OSTI]

    Sriraman, Bharath

    -Index: 17 scholar.google.com Copyright - Jan Feyereisl (v.1.211) Project Page view publications AuthorA Google Scholar gadget for calculating author citations and other statistical information regarding publications. more... Statistics: Citations for 'Sriraman.B' : 1153 Cited Publications: 100 H

  19. Astrophysical Thermonuclear Functions for Boltzmann-Gibbs Statistics and Tsallis Statistics

    E-Print Network [OSTI]

    R. K. Saxena; A. M. Mathai; H. J. Haubold

    2004-06-22

    We present an analytic proof of the integrals for astrophysical thermonuclear functions which are derived on the basis of Boltzmann-Gibbs statistical mechanics. Among the four different cases of astrophysical thermonuclear functions, those with a depleted high-energy tail and a cut-off at high energies find a natural interpretation in q-statistics.

  20. Introduction to CEAL Online Statistics I

    E-Print Network [OSTI]

    Doll, Vickie; Liu, Wen-ling

    2014-09-25

    CEAL Statistics Open Data, 1957- CEAL stats workshop I 109/25/2014 CEAL Statistics Open Data, 1957- •Table View (Basic and Advance) •Graph View (Basic and Advance) •Quick View •PDF CEAL stats workshop I 209/25/2014 Table View (Basic) CEAL stats... workshop I 309/25/2014 Table View (Basic) Search the database with year(s) and libraries, and view all the data and fields available in individual tables. CEAL stats workshop I 409/25/2014 Table View (Basic) Choose multiple years and libraries (use...

  1. Spin, Statistics, and Reflections, II. Lorentz Invariance

    E-Print Network [OSTI]

    Bernd Kuckert; Reinhard Lorenzen

    2005-12-21

    The analysis of the relation between modular P$_1$CT-symmetry -- a consequence of the Unruh effect -- and Pauli's spin-statistics relation is continued. The result in the predecessor to this article is extended to the Lorentz symmetric situation. A model $\\G_L$ of the universal covering $\\widetilde{L_+^\\uparrow}\\cong SL(2,\\complex)$ of the restricted Lorentz group $L_+^\\uparrow$ is modelled as a reflection group at the classical level. Based on this picture, a representation of $\\G_L$ is constructed from pairs of modular P$_1$CT-conjugations, and this representation can easily be verified to satisfy the spin-statistics relation.

  2. On the explanation for quantum statistics

    E-Print Network [OSTI]

    Simon Saunders

    2005-11-15

    The concept of classical indistinguishability is analyzed and defended against a number of well-known criticisms, with particular attention to the Gibbs' paradox. Granted that it is as much at home in classical as in quantum statistical mechanics, the question arises as to why indistinguishability, in quantum mechanics but not in classical mechanics, forces a change in statistics. The answer, illustrated with simple examples, is that the equilibrium measure on classical phase space is continuous, whilst on Hilbert space it is discrete. The relevance of names, or equivalently, properties stable in time that can be used as names, is also discussed.

  3. Spectral statistics of nearly unidirectional quantum graphs

    E-Print Network [OSTI]

    Maram Akila; Boris Gutkin

    2015-08-19

    The energy levels of a quantum graph with time reversal symmetry and unidirectional classical dynamics are doubly degenerate and obey the spectral statistics of the Gaussian Unitary Ensemble. These degeneracies, however, are lifted when the unidirectionality is broken in one of the graph's vertices by a singular perturbation. Based on a Random Matrix model we derive an analytic expression for the nearest neighbour distribution between energy levels of such systems. As we demonstrate the result agrees excellently with the actual statistics for graphs with a uniform distribution of eigenfunctions. Yet, it exhibits quite substantial deviations for classes of graphs which show strong scarring.

  4. Black Hole Thermodynamics and Statistical Mechanics

    E-Print Network [OSTI]

    Steven Carlip

    2008-07-28

    We have known for more than thirty years that black holes behave as thermodynamic systems, radiating as black bodies with characteristic temperatures and entropies. This behavior is not only interesting in its own right; it could also, through a statistical mechanical description, cast light on some of the deep problems of quantizing gravity. In these lectures, I review what we currently know about black hole thermodynamics and statistical mechanics, suggest a rather speculative "universal" characterization of the underlying states, and describe some key open questions.

  5. On statistical methods of structure function extraction

    E-Print Network [OSTI]

    S. N. Sevbitov; T. V. Shishkina; I. L. Solovtsov

    2007-11-29

    Several methods of statistical analysis are proposed and analyzed in application for a specific task -- extraction of the structure functions from the cross sections of deep inelastic interactions of any type. We formulate the method based on the orthogonal weight functions and on an optimization procedure of errors minimization as well as methods underlying common $\\chi^2$ minimization. Effectiveness of these methods usage is analyzed by comparison of the statistical parameters such as bias, extraction variance etc., for sample deep inelastic scattering data set.

  6. GIS, SPATIAL STATISTICAL GRAPHICS, AND FOREST HEALTH.

    E-Print Network [OSTI]

    Symanzik, Jürgen

    , and Jürgen Symanzik ABSTRACT This paper discusses the use of a geographic information systems (GIS), Arcview, into a geographic information system (GIS), Arcview 2.1 (ESRI 1995), and its use in the statistical analysis of spa Program (EMAP). The field data are augmented with concomitant geographic information, including Landsat

  7. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    Stephens, Matthew

    of Statistics The University of Chicago The Weekend Effect of Return on Crude Oil Prices THURSDAY, February 26, 2009 at 11:00 AM 110 Eckhart Hall, 5734 S. University Avenue ABSTRACT Crude oil prices experienced movements of WTI crude oil prices can be observed during the period from 1986 to 2008. Spectral analysis

  8. Remarks on statistical errors in equivalent widths

    E-Print Network [OSTI]

    Klaus Vollmann; Thomas Eversberg

    2006-07-03

    Equivalent width measurements for rapid line variability in atomic spectral lines are degraded by increasing error bars with shorter exposure times. We derive an expression for the error of the line equivalent width $\\sigma(W_\\lambda)$ with respect to pure photon noise statistics and provide a correction value for previous calculations.

  9. Purpose of journals Some popular statistical journals

    E-Print Network [OSTI]

    Reich, Brian J.

    Outline · Purpose of journals · Some popular statistical journals · How to structure a journal article · What makes a good journal article? · Editorial structure of a journal · The review process · Submitting a paper · Acting as a referee 1 #12;Purpose of journals Research: The mechanism by which knowledge

  10. Statistical Consistency With Dempster's Rule on

    E-Print Network [OSTI]

    Valtorta, Marco

    Parameters Stephen D. Durham Department of Statistics, University of South Carolina, Columbia, South Carolina Jeffery S. Smoika MEMC Electronic Materials, Inc., Spartanburg, South Carolina Marco Valtorta Department of Computer Science, University of South Carolina, Columbia, South Carolina ABSTRACT This paper defines

  11. SHORT REVIEW Statistical tests of selective neutrality

    E-Print Network [OSTI]

    Nielsen, Rasmus

    SHORT REVIEW Statistical tests of selective neutrality in the age of genomics RASMUS NIELSEN genomic data for traces of selection provides a powerful tool for identifying genomic regions genomic data sets has invigorated the ®eld of molecular population genetics and spurred new controversies

  12. URI WILENSKY STATISTICAL MECHANICS FOR SECONDARY SCHOOL

    E-Print Network [OSTI]

    Wilensky, Uri

    , is made accessible to these students through the medium of a computer-based modeling environment, Net exploring and constructing computer-based models of that content. This paper presents a case study of a high of a secondary teacher and students constructing and exploring NetLogo models of statistical mech- anical

  13. Spectral statistics for scaling quantum graphs

    E-Print Network [OSTI]

    Yu. Dabaghian

    2006-08-09

    The explicit solution to the spectral problem of quantum graphs is used to obtain the exact distributions of several spectral statistics, such as the oscillations of the quantum momentum eigenvalues around the average, $\\delta k_{n}=k_{n}-\\bar k_{n}$, and the nearest neighbor separations, $s_{n}=k_{n}-k_{n-1}$.

  14. STATISTICAL ANALYSIS OF PROTEIN FOLDING KINETICS

    E-Print Network [OSTI]

    Dinner, Aaron

    STATISTICAL ANALYSIS OF PROTEIN FOLDING KINETICS AARON R. DINNER New Chemistry Laboratory for Protein Folding: Advances in Chemical Physics, Volume 120. Edited by Richard A. Friesner. Series Editors Experimental and theoretical studies have led to the emergence of a unified general mechanism for protein

  15. A Statistical Framework for Spatial Comparative Genomics

    E-Print Network [OSTI]

    A Statistical Framework for Spatial Comparative Genomics Rose Hoberman May 2007 CMU-CS-07, or the U.S. Government. #12;Keywords: spatial comparative genomics, comparative genomics, gene clusters, max-gap clusters, gene teams, whole genome duplication, paralogons, synteny, ortholog detection #12

  16. Differential Privacy and Robust Statistics Cynthia Dwork

    E-Print Network [OSTI]

    Lei, Jing

    for differentially private mechanisms, which we call Propose-Test-Release (PTR), and for which we give a formal, the design of insensitive algorithms can require considerable re-thinking of existing algorithms. Much. Most well-known elementary statistical methods are para- metric. For example, given data samples x1

  17. MINI-WORKSHOP ANNOUNCEMENT Department of Statistics

    E-Print Network [OSTI]

    Stephens, Matthew

    MINI-WORKSHOP ANNOUNCEMENT Department of Statistics Space-time Modeling of Air Pollution Levels and deposition values of various air pollutants. We propose a space-time modeling approach for combining CMAQ output with observations to produce an improved map of air pollution levels. Methodologies to evaluate

  18. INDIAN STATISTICAL INSTITUTE SQC & OR Unit

    E-Print Network [OSTI]

    Bandyopadhyay, Antar

    INDIAN STATISTICAL INSTITUTE SQC & OR Unit Bangalore Announces Certification Program for SIX SIGMA.isi@gmail.com, sanjitisi@yahoo.co.in 6th - 8th, 12th ­ 14th September; 2014 Bangalore #12;EXPECTATION! Six Sigma is like, Dean Witter, Discover & Co. (Report on Business Magazine, October 1997) Six Sigma initiative has

  19. INDIAN STATISTICAL INSTITUTE SQC & OR Unit

    E-Print Network [OSTI]

    Bandyopadhyay, Antar

    INDIAN STATISTICAL INSTITUTE SQC & OR Unit Bangalore Announces Certification Program for SIX SIGMA.isi@gmail.com, sanjitisi@yahoo.co.in #12;EXPECTATION! Six Sigma is like that old Wella Balsam shampoo commercial: `She Magazine, October 1997) Six Sigma initiative has become a rage. Every organization wants to implement Six

  20. Communication as information use: insights from statistical

    E-Print Network [OSTI]

    Stephens, David W.

    3 Communication as information use: insights from statistical decision theory caitlin r. kight Communication Theory: Information and Influence, ed. Ulrich Stegmann. Published by Cambridge University Press focuses on the latter, which forms the basis of animal communication. Animal communication has been

  1. Information Theory and Statistical Physics - Lecture Notes

    E-Print Network [OSTI]

    Merhav, Neri

    2010-01-01

    This document consists of lecture notes for a graduate course, which focuses on the relations between Information Theory and Statistical Physics. The course is aimed at EE graduate students in the area of Communications and Information Theory, as well as to graduate students in Physics who have basic background in Information Theory. Strong emphasis is given to the analogy and parallelism between Information Theory and Statistical Physics, as well as to the insights, the analysis tools and techniques that can be borrowed from Statistical Physics and `imported' to certain problem areas in Information Theory. This is a research trend that has been very active in the last few decades, and the hope is that by exposing the student to the meeting points between these two disciplines, we will enhance his/her background and perspective to carry out research in the field. A short outline of the course is as follows: Introduction; Elementary Statistical Physics and its Relation to Information Theory; Analysis Tools in ...

  2. Multivariate Statistics Unit code: MATH38061

    E-Print Network [OSTI]

    Sidorov, Nikita

    MATH38061 Multivariate Statistics Unit code: MATH38061 Credit Rating: 10 Unit level: Level 3. Aims To familiarise students with the ideas and methodology of certain multivariate methods together sets of data are multivariate in that they consist of observations on several different variables

  3. Multivariate Statistics Unit code: MATH48061

    E-Print Network [OSTI]

    Sidorov, Nikita

    MATH48061 Multivariate Statistics Unit code: MATH48061 Credit Rating: 15 Unit level: Level 4. Aims To familiarise students with the ideas and methodology of certain multivariate methods together sets of data are multivariate in that they consist of observations on several different variables

  4. Linearity -statistics 1.1B training

    E-Print Network [OSTI]

    Linearity - statistics IPAT 1.1B training 300M training D0 resolution is evaluated using 100k single muon events (same events in all 3 plots). Red is the default 11L FTK bank trained using 300M muons on narrow beam of muons (central eta, fixed phi, high fixed pT). Using two types of training: default FTK

  5. Presented by Statistical Physics of Fracture

    E-Print Network [OSTI]

    Presented by Statistical Physics of Fracture: Recent Advances through High-Performance Computing) ­ Phys. Rev. E 71 (2005a, 2005b, 2005c); 73 (2006a, 2006b) ­ Adv. Phys. (2006); Int. J. Fracture (2006); Int. J. Fracture (2008a, 2008b) ­ J. Phys. D (2009); J. Chem. Phys. (2009); Phys. Rev. B (2009

  6. Seismic imaging using higher order statistics 

    E-Print Network [OSTI]

    Srinivasan, Karthik

    1999-01-01

    the resulting algorithm is a cross-correlation (second order statistics) operation whose region of support is limited to the bandwidth of the source signal. This is not the case for non-vanishing higher order cumulates where the support region can be extended...

  7. Baseballs and Barrels: World Statistics Day

    Broader source: Energy.gov [DOE]

    Statistics don’t just help us answer trivia questions – they also help us make intelligent decisions. For example, if I heat my home with natural gas, I’m probably interested in what natural gas prices are likely to be this winter.

  8. Heat pump market and statistics report 2013

    E-Print Network [OSTI]

    Oak Ridge National Laboratory

    #12;Heat pump market and statistics report 2013 Thomas Nowak Secretary General European Heat Pump Summit 15.10./16.10.2013 | Nuremberg #12;European Heat Pump Association (EHPA) · 107 members from 22 countries (status 08/2013) ­ Heat pump manufacturers ­ Component manufacturers ­ National associations

  9. Problems on Non-Equilibrium Statistical Physics 

    E-Print Network [OSTI]

    Kim, Moochan

    2011-08-08

    Four problems in non-equilibrium statistical physics are investigated: 1. The thermodynamics of single-photon gas; 2. Energy of the ground state in Multi-electron atoms; 3. Energy state of the H2 molecule; and 4. The Condensation behavior in N...

  10. STATISTICS 579 R Tutorial : Programming in R

    E-Print Network [OSTI]

    Fall 2005 STATISTICS 579 R Tutorial : Programming in R 1. Conditional computation in R: The basic control structure available in R for conditional computation is of the form if (cond) expr-1 else expr-2 where cond is an expression that evaluates to a logical value, expr-1 is an R expression

  11. SYLLABUS MATH 7608 STATISTICAL PROGRAMMING WITH R

    E-Print Network [OSTI]

    Hagen, Thomas

    SYLLABUS ­ MATH 7608 STATISTICAL PROGRAMMING WITH R SPRING 2014 11:30- 12:25 MWF DUNN HALL 207:00-4:00 MW or by appointment Textbook: Scientific Programming and Simulation Using R, by Owen Jones, Robert will have a due date assigned and will be turned in via drop box. The program must run in R without error

  12. statistical physics canonical ensemble Uranium Centrifuges

    E-Print Network [OSTI]

    statistical physics canonical ensemble Uranium Centrifuges The easiest type of nuclear weapon of the physics behind crude uranium enrichment methods. 2 The centrifuge concept is a very generic way of trying the uranium, we remove gas from the ends of the centrifuge, where the heavier uranium atoms are more

  13. Fractal statistics, fractal index and fractons

    E-Print Network [OSTI]

    Wellington da Cruz

    2000-10-10

    The concept of fractal index is introduced in connection with the idea of universal class $h$ of particles or quasiparticles, termed fractons, which obey fractal statistics. We show the relation between fractons and conformal field theory(CFT)-quasiparticles taking into account the central charge $c[\

  14. Daily Precipitation Statistics: An Intercomparison between

    E-Print Network [OSTI]

    Zeng, Ning

    Daily Precipitation Statistics: An Intercomparison between NCEP Reanalyses and Observations Vernon-2010. Resolution T382 (~0.3x0.3 degrees). #12;R1, R2, CFSR: Comparison to OI Station-based Precipitation Analyses station-based daily precipitation analysis data set (1979-2006). · The high-resolution reanalysis (CFSR

  15. A Statistics-Guided Approach to Precise Characterization of Nanowire

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    Wang, Xudong

    A Statistics-Guided Approach to Precise Characterization of Nanowire Morphology Fei Wang and Department of Statistics, University of WisconsinOMadison, Madison, Wisconsin 53706. § These authors statistical ideas and means to establish a statistics-guided approach to precise char- acterization

  16. Montana State University 1 Ph.D. in Statistics

    E-Print Network [OSTI]

    Maxwell, Bruce D.

    Montana State University 1 Ph.D. in Statistics Ph.D. in Statistics Program Requirements The Ph.D. program in statistics at Montana State University prepares students for academic, industrial, business, or government employment. To earn a Ph.D. in statistics, a student must pass a qualifying exam

  17. n-Gram Statistics in MapReduce

    E-Print Network [OSTI]

    Waldmann, Uwe

    Computing n-Gram Statistics in MapReduce Klaus Berberich (kberberi@mpi-inf.mpg.de) Srikanta Bedathur (bedathur@iiitd.ac.in) #12;Computing n-Gram Statistics in MapReduce ­ Klaus Berberich / 26 n-Gram Statistics Statistics about variable-length word sequences (e.g., lord of the rings, at the end

  18. Chapter 1 The Nature of Probability and Statistics

    E-Print Network [OSTI]

    Hong, Don

    Chapter 1 The Nature of Probability and Statistics 1.1 Introduction Definition. Statistics based on probability theory. This chapter introduces the basic concepts of probability and statistics by answering questions like: · what are the branches of statistics · what are data · how are samples selected 1

  19. Teaching computing in statistical theory courses David R. Hunter

    E-Print Network [OSTI]

    Hunter, David

    Teaching computing in statistical theory courses David R. Hunter Department of Statistics of Gentle (2004), who states that ". . . all graduate programs in statistics should offer at least one The Pennsylvania State University June 27, 2005 Abstract Graduate-level instruction in statistical computing need

  20. BS in ACTUARIAL SCIENCE (695224) MAP Sheet Department of Statistics

    E-Print Network [OSTI]

    Seamons, Kent E.

    of Statistical Results Stat 330 Introduction to Regression Stat 340 Inference Program Requirements: Complete 496R Academic Internship: Statistics Stat 497R Introduction to Statistical Research RecommendedBS in ACTUARIAL SCIENCE (695224) MAP Sheet Department of Statistics For students entering