Sample records for nf metropolitan statistical

  1. Metropolitan Transportation Plan 2035

    E-Print Network [OSTI]

    Tyler Area Metropolitan Planning Organization

    2009-12-04T23:59:59.000Z

    Adopted by the Tyler Area MPO Policy Committee December 4, 2009 METROPOLITAN TRANSPORTATION PLAN 2035 Revised April 22, 2010 Adopted by the Tyler Area MPO Policy Committee December 4, 2009 Amended/Revised April 22, 2010 Prepared by: Bucher..., Willis, and Ratliff Corporation 1828 East Southeast Loop 323, Suite 202 Tyler, Texas 75701 903.581.7844 This Document Serves as an Update to the Tyler Area Metropolitan Transportation Plan 2030. Portions of that Document were Unchanged and Appear...

  2. TransBorder 2035 Metropolitan Transportation Plan

    E-Print Network [OSTI]

    El Paso Metropolitan Planning Organization

    2007-11-16T23:59:59.000Z

    i TransBorder 2035 Metropolitan Transportation Plan November 16, 2007 El Paso Metropolitan Planning Organization www.elpasompo.org ii TransBorder 2035 Metropolitan Transportation Plan November 16, 2007... El Paso Metropolitan Planning Organization www.elpasompo.org iii TransBorder 2035 Metropolitan Transportation Plan November 16, 2007 El Paso Metropolitan Planning Organization www.elpasompo.org iv Trans...

  3. Statistics

    E-Print Network [OSTI]

    Rubin, Herman [bio] Professor of Statistics and Mathematics PhD: University of Chicago 1948. Office: MATH 550; Phone: +1 765 49-46054; Email: ...

  4. Baton Rouge Metropolitan Transportation Plan Update

    E-Print Network [OSTI]

    Capital Region Planning Commission

    (028) SUBMITTED TO: LOUISIANA DEPARTMENT OF TRANSPORTATION AND DEVELOPMENT SUBMITTED BY: IN ASSOCIATION WITH: & FINAL Metropolitan Transportation Plan Update Baton Rouge, LA... ............................189? X. APPENDIX .........................................................................................................................195? ? Metropolitan Transportation Plan Update...

  5. Metropolitan Transportation Plan 2009-2035

    E-Print Network [OSTI]

    South Central Planning and Development Commission

    2009-05-14T23:59:59.000Z

    ?? Metropolitan? Transportation?Plan? 2009?2035? ? This?document?is?the?long?range?transportation?plan?for?the?Houma?Thibodaux? Metropolitan?Planning?Organization.??It?represents?the?staged?implementation?of? the?transportation...?needs?in?the?Houma?Thibodaux?urbanized?area,?extending?from? 2009?to?2035.? ? Adopted?on?May?14,?2009? Prepared?by?the?South?Central?Planning?and?Development?Commission? ? Adopted My 14, 2009 [METROPOLITAN TRANSPORTATION PLAN] 2 Contents Chapters Page 1 Introduction 5 2 Existing...

  6. The Metropolitan Surface Water Management Act (Minnesota)

    Broader source: Energy.gov [DOE]

    The Metropolitan Surface Water Management Act aims to protect, preserve, and use natural, surface, and groundwater storage and retention systems; identify and plan for means to improve and protect...

  7. Metropolitan Accessibility and Transportation Sustainability:Sustainability

    E-Print Network [OSTI]

    Papalambros, Panos

    Metropolitan Accessibility and Transportation Sustainability:Sustainability: Comparative Reduce (fulfillment of)Promote Sustainability: Meet needs of (fulfillment of) needs present Institute SMART Sustainable Mobility and Accessibility Research andSMART Sustainable Mobility

  8. U.S. Metropolitan Spatial Structure and Employment Growth

    E-Print Network [OSTI]

    Huang, Xiaoyan

    2014-08-13T23:59:59.000Z

    This study explores the influence of US metropolitan spatial structure evolution on regional employment growth rate. The first part of this study investigates the evolution of US metropolitan spatial structures from 2000 to 2010. At the macro level...

  9. Learning sustainable metropolitan development for european students of planning

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    1 Learning sustainable metropolitan development for european students of planning Serrano José, project assessment, sustainable developement, team work Introduction Metropolitan areas are experiencing ways which are more sustainable than others. In our planning training, we teach sustainable development

  10. METROPOLITAN TRANSPORTATION SUPPORT INITIATIVE (METSI) QUARTERLY REPORT

    E-Print Network [OSTI]

    Illinois at Chicago, University of

    METROPOLITAN TRANSPORTATION SUPPORT INITIATIVE (METSI) QUARTERLY REPORT for the quarter ending over 50%) of residents throughout the state of Illinois would support a 5 cent per gallon gas tax if the proceeds were to improve roads and transit. The other survey, 2002 Market Survey undertaken by RTA examined

  11. Metropolitan Transportation Plan Fiscal Year 2010 - 2035

    E-Print Network [OSTI]

    Corpus Christi Metropolitan Planning Organization

    2009-12-03T23:59:59.000Z

    Approved by the Transportation Policy Committee December 3, 2009 Disclaimer Statement: The preparation of this report has been financed in part through grant[s] from the Federal Highway Administration and Federal... Transit Administration, U.S. Department of Transportation, under the State Planning and Research Program, Section 505 [or Metropolitan Planning Program, Section 104(f)] of Title 23, U.S. Code. The contents of this report do not necessarily reflect...

  12. Connections 2035 The Waco Metropolitan Transportation Plan

    E-Print Network [OSTI]

    Waco Metropolitan Planning Organization

    2010-02-03T23:59:59.000Z

    Administration, Federal Transit Administration, and the Texas Department of Transportation. Preface The Waco Metropolitan Planning Organization has prepared this plan in compliance with the Safe, Accountable, Flexible and Efficient Transportation Equity Act...: A Legacy for Users (SAFETEA-LU). The preparation of this plan has been funded in part through grants by the Federal Highway Administration, the Federal Transit Administration and the Texas Department of Transportation. The contents...

  13. Metropolitan Transportation Plan 2005-2030

    E-Print Network [OSTI]

    Santa Fe Metropolitan Planning Organization

    1999-01-01T23:59:59.000Z

    The Santa Fe Metropolitan Transportation Plan 2005-2030 (MTP) replaces the Santa Fe MPO Long Range Transportation Plan 2000-2020 as a guide for developing a safer, more efficient and effective transportation system that serves the residents..., commuters and visitors to Santa Fe. The theme of ?providing interconnected options for more travel choices? reflects a strong public call for a safer and more functional interconnected network of roads, trails and transit routes that gives people a choice...

  14. Amarillo Metropolitan Transportation Plan 2010-2035

    E-Print Network [OSTI]

    Amarillo Metropolitan Planning Organization

    2009-10-15T23:59:59.000Z

    , natural resources, environmental protection, conservation, and historic preservation concerning the development of long- and short- range transportation plans. MPO maintains a website www.amarillompo.org that includes this Metropolitan Transportation... Commissioner City of Amarillo Alan M. Taylor City Manager City of Amarillo Howard Holland, P.E. District Engineer TxDOT Kenneth Petr, P.E. Dir. of Transportation Planning & Development TxDOT Judge Arthur Ware County Judge Potter County H.R. Kelly County...

  15. Metropolitan Road Traffic Simulation on FPGAs.

    SciTech Connect (OSTI)

    Tripp J. L. (Justin L.); Mortveit, H. S. (Henning S.); Hansson, A. A. (Anders A.); Gokhale, M. (Maya)

    2005-01-01T23:59:59.000Z

    This work demonstrates that road traffic simulation of entire metropolitan areas is possible with reconfigurable supercomputing that combines 64-bit microprocessors and FPGAs in a high bandwidth, low latency interconnect. Previously, traffic simulation on FPGAs was limited to very short road segments or required a very large number of FPGAs. Our data streaming approach overcomes scaling issues associated with direct implementations and still allows for high-level parallelism by dividing the data sets between hardware and software across the reconfigurable supercomputer. Using one FPGA on the Cray XD1 supercomputer, we are able to achieve a 34.4 x speed up over the AMD microprocessor. System integration issues must be optimized to exploit this speedup in the overall simulation.

  16. The structure of agriculture in metropolitan and nonmetropolitan America

    E-Print Network [OSTI]

    Scott, Michelle L

    2003-01-01T23:59:59.000Z

    variation of agristructure. Furthermore, total crop, grain, cotton, nursery/greenhouse, fruit/vegetable, and "other crop" sales revenues varied by metropolitan proximity, region, and farm system size. Ordinary least squares regression was employed...

  17. METROPOLITAN REPORT Economic Indicators for the New Orleans Area

    E-Print Network [OSTI]

    Kulp, Mark

    gained. Growth, while continuing, has slowed. · Construction, driven by recovery activity, is stronger or July 2007. Employment data at the metropolitan level under- went an enormous revision by the Louisiana

  18. american metropolitan areas: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    all-to-all traffic and regular ... Guan, Kyle C. 11 Impact of primary formaldehyde on air pollution in the Mexico City Metropolitan Area MIT - DSpace Summary: Formaldehyde (HCHO)...

  19. avoiding metropolitan areas: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    all-to-all traffic and regular ... Guan, Kyle C. 10 Impact of primary formaldehyde on air pollution in the Mexico City Metropolitan Area MIT - DSpace Summary: Formaldehyde (HCHO)...

  20. atlanta metropolitan area: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    all-to-all traffic and regular ... Guan, Kyle C. 10 Impact of primary formaldehyde on air pollution in the Mexico City Metropolitan Area MIT - DSpace Summary: Formaldehyde (HCHO)...

  1. Performance Measurement in Small Texas Metropolitan Planning Organizations

    E-Print Network [OSTI]

    Moore, Devin 1984-

    2012-10-16T23:59:59.000Z

    place including a rise in prominence of the Metropolitan Planning Organization (MPO). The public, state and local agencies, and other stakeholders are mutually served by the regional MPO to assure that transportation funding allocation and project...

  2. Metropolitan Edison Company SEF Loans (FirstEnergy Territory)

    Broader source: Energy.gov [DOE]

    FirstEnergy (formerly GPU) established the Metropolitan Edison Company Sustainable Energy Fund in 2000 with an initial contribution of $5.7 million. The fund later received an additional...

  3. The interests of landowners on the metropolitan fringe

    E-Print Network [OSTI]

    Molinsky, Jennifer H. (Jennifer Hrabchak)

    2005-01-01T23:59:59.000Z

    Numerous authors have noted that the patchy, sprawling pattern of development characterizing the metropolitan fringe results in part from the decisions of individual landowners regarding the use, subdivision, development, ...

  4. Efficient detection of contagious outbreaks in massive metropolitan encounter networks

    E-Print Network [OSTI]

    Sun, Lijun

    Physical contact remains difficult to trace in large metropolitan networks, though it is a key vehicle for the transmission of contagious outbreaks. Co-presence encounters during daily transit use provide us with a city-scale ...

  5. New Orleans Urbanized Area Metropolitan Transportation Plan FY 2032

    E-Print Network [OSTI]

    New Orleans Urbanized Area Regional Planning Commission

    2007-06-12T23:59:59.000Z

    which are more economical or which have less environmental eff ects while achieving similar transportation objectives. Burgeoning corridors such as the corridor between the Louis Armstrong International Airport and the Central Business District...2 0 23 F Y Metropolitan Transportation Plan New Orleans Urbanized AreaNew Regional Planning Commission Jefferson, Orleans Plaquemines, St. Bernard and St. Tammany Parishes, Louisiana June 12, 2007 Metropolitan Transportation Plan New Orleans...

  6. Hot Springs Metropolitan Planning Organization 2030 Long Range Transportation Plan

    E-Print Network [OSTI]

    Hot Springs Metropolitan Planning Organization

    2005-11-03T23:59:59.000Z

    Federal Highway Administration Federal Transit Administration 2030 Long Range Transportation Plan for the Hot Springs Area Metropolitan Planning Organization This LRTP has been funded with federal Metropolitan Planning (PL) funds through... the Federal Highway Administration, Section 5303 funds through the Federal Transit Administration, the State of Arkansas, and participating agency local match funds. HSA-MPO 100 Broadway Terrace Hot Springs, AR 71901 501-321-4804 HSA...

  7. Metropolitan area network support at Fermilab

    SciTech Connect (OSTI)

    DeMar, Phil; Andrews, Chuck; Bobyshev, Andrey; Crawford, Matt; Colon, Orlando; Fry, Steve; Grigaliunas, Vyto; Lamore, Donna; Petravick, Don; /Fermilab

    2007-09-01T23:59:59.000Z

    Advances in wide area network service offerings, coupled with comparable developments in local area network technology have enabled many research sites to keep their offsite network bandwidth ahead of demand. For most sites, the more difficult and costly aspect of increasing wide area network capacity is the local loop, which connects the facility LAN to the wide area service provider(s). Fermilab, in coordination with neighboring Argonne National Laboratory, has chosen to provide its own local loop access through leasing of dark fiber to nearby network exchange points, and procuring dense wave division multiplexing (DWDM) equipment to provide data channels across those fibers. Installing and managing such optical network infrastructure has broadened the Laboratory's network support responsibilities to include operating network equipment that is located off-site, and is technically much different than classic LAN network equipment. Effectively, the Laboratory has assumed the role of a local service provider. This paper will cover Fermilab's experiences with deploying and supporting a Metropolitan Area Network (MAN) infrastructure to satisfy its offsite networking needs. The benefits and drawbacks of providing and supporting such a service will be discussed.

  8. Sustainable metropolitan growth strategies : exploring the role of the built environment

    E-Print Network [OSTI]

    Diao, Mi, Ph. D. Massachusetts Institute of Technology

    2010-01-01T23:59:59.000Z

    The sustainability of metropolitan areas has been considered one of the most significant social challenges worldwide. Among the various policy options to achieve sustainable metropolitan growth, smart-growth strategies ...

  9. NF Energy Saving Corp | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov YouKizildere I Geothermal Pwer PlantMunhall, Pennsylvania: Energy Resources JumpNEF Advisors LLC JumpNF Energy Saving Corp

  10. Cooling energy savings potential of light-colored roofs for residential and commercial buildings in 11 US metropolitan areas

    SciTech Connect (OSTI)

    Konopacki, S.; Akbari, H.; Pomerantz, M.; Gabersek, S.; Gartland, L.

    1997-05-01T23:59:59.000Z

    Light-colored roofs reflect more sunlight than dark roofs, thus they keep buildings cooler and reduce air-conditioning demand. Typical roofs in the United States are dark, which creates a potential for savings energy and money by changing to reflective roofs. In this report, the authors make quantitative estimates of the impact of roof color by simulating prototypical buildings with light- and dark-colored roofs and calculating savings by taking the differences in annual cooling and heating energy use, and peak electricity demand. Monetary savings are calculated using local utility rates. Savings are estimated for 11 U.S. Metropolitan Statistical Areas (MSAs) in a variety of climates.

  11. Jonesboro Metropolitan Planning Organization 2030 Long Range Transportation Plan

    E-Print Network [OSTI]

    Jonesboro Metropolitan Planning Organization

    southern boundary. The airport is connected to the roadway system by Airport Road connecting Nettleton Avenue and US 49 (Johnson Avenue). According to the Federal Aviation Administration (FAA) information dated July 7, 2005, there are about 123...Jonesboro Metropolitan Planning Organization In cooperation with the Arkansas State Highway and Transportation Department United States Department of Transportation Federal Highway Administration Federal Transit Administration...

  12. Metropolitan Ethernet Network: A Move from LAN to MAN

    E-Print Network [OSTI]

    California at Davis, University of

    transformed from a CSMA/CD technology providing low throughput to a full duplex link increasing the throughput the transformation of Ethernet from the mainstream LAN technology to the possible adoption for metropolitan area networks (MENs). This paper will introduce the movement from basic Ethernet to the carrier grade Ethernet

  13. Energy Management Program atEnergy Management Program at Metropolitan Water District ofMetropolitan Water District of

    E-Print Network [OSTI]

    Keller, Arturo A.

    ;BackgroundBackground Climate change & global warming Greenhouse gas emissions Legislation ­ Governor's Executive Order S-3-05 ­ AB32: Reduction of GHG Emissions Climate change & global warming Greenhouse gas,385 GWh 2005 Metropolitan elect. usage = 1,940 GWh (0.7% of Calif.) ­ Enough electricity for 280,000 homes

  14. Statistics Overall Statistics

    E-Print Network [OSTI]

    Czarnecki, Krzysztof

    2012 Beaver Computing Challenge Results Sponsor: 1 #12;Statistics Overall Statistics Number.24/6 Glasses: 1.74/4 Text Machine: 5.54/8 Hierarchical Structure: 2.98/6 Bebrocarina: 2.14/4 Beaver Navigation: 5.06/8 Beaver Pyramid: 3.23/6 Change Direction: 1.45/4 Power Generation: 5.56/8 Rotating Puzzle: 5

  15. NF-?B Fans the Flames of Lung Carcinogenesis

    E-Print Network [OSTI]

    Jacks, Tyler E.

    This perspective on Deng et al. (beginning on p. 424 in this issue of the journal) examines the link between NF-?B and lung tumorigenesis. Experiments in genetically engineered mouse models of lung cancers are elucidating ...

  16. Statistical Sciences

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of Experiments Reliability Bayesian Methods Statistical Computation Statistical Graphics and Visualization Analysis of Measurement Systems Projects Data Analysis System...

  17. Statistical Laboratory & Department of Statistics

    E-Print Network [OSTI]

    Statistical Laboratory & Department of Statistics Annual Report July 1, 2005 to December 31, 2006...............................................33 Statistical Computing Section ......................................34 CSSM and statistical methodology in the nutritional sciences. We were also very pleased to secure a permanent lecturer

  18. Universality of the Nf=2 Running Coupling

    E-Print Network [OSTI]

    K. Murano; S. Aoki; S. Takeda; Y. Taniguchi

    2009-03-06T23:59:59.000Z

    We investigate universality of the Nf=2 running coupling in the Sch\\"odinger functional scheme, by calculating the step scaling function in lattice QCD with the renorm alization group (RG) improved gauge action at both weak(u=0.9796) and strong(u=3.3340) couplings, where u=\\bar{g}^2_SF with \\bar{g}_SF being the running coupling in this scheme. In our main calculations, we use the tree-level value for O(a) improvement coefficients of boundary gauge fields. In addition we employ the 1-loop value for them in order to see how scaling behaviours are affected by them. In the continuum limit, the step scaling function obtained from the RG improved gauge actions agrees with the previous result obtained from the plaquette action within errors at both couplings, though errors of our result are larger. Combined fits using all data with the RG improved action as well as the plaquette action reduce errors in the continuum limit by 2% at the weak coupling and 22% at the strong coupling.

  19. Department of Statistics STATISTICS COLLOQUIUM

    E-Print Network [OSTI]

    Department of Statistics STATISTICS COLLOQUIUM ERIC KOLACZYK Department of Statistics Boston University Statistical Analysis of Network Data: (Re)visiting the Foundations MONDAY, October 13, 2014, at 4, statistical methods and modeling have been central to these efforts. But how well do we truly understand

  20. 32. Statistics 1 32. STATISTICS

    E-Print Network [OSTI]

    Masci, Frank

    32. Statistics 1 32. STATISTICS Revised September 2007 by G. Cowan (RHUL). This chapter gives an overview of statistical methods used in High Energy Physics. In statistics, we are interested in using's validity or to determine the values of its parameters. There are two main approaches to statistical

  1. Statistical Laboratory & Department of Statistics

    E-Print Network [OSTI]

    by the American Statistical Association. Dean Isaacson and Mark Kaiser were instrumental in garnering a NationalStatistical Laboratory & Department of Statistics Annual Report July 1, 2002 to June 30, 2003 IOWA Chair of the Department of Statistics and Director of the Statistical Laboratory in November, 2002. Dean

  2. Haploid reporter screens aimed at identification of NF-kappaB regulators

    E-Print Network [OSTI]

    Lee, Clarissa Ci

    2014-01-01T23:59:59.000Z

    Nuclear factor-kappaB (NF-KB) is a family of transcription factors that are essential for execution of both the innate and the adaptive immune response. NF-KB regulates hundreds of genes involved in critical processes such ...

  3. Kaon semileptonic vector form factor with $N_f=2+1+1$ Twisted Mass fermions

    E-Print Network [OSTI]

    Nuria Carrasco; Paolo Lami; Vittorio Lubicz; Eleonora Picca; Lorenzo Riggio; Silvano Simula; Cecilia Tarantino

    2014-10-27T23:59:59.000Z

    We investigate the vector form factor relevant for the $K_{\\ell 3}$ semileptonic decay using maximally twisted-mass fermions with 4 dynamical flavours ($N_f=2+1+1$). Our simulations feature pion masses ranging from $210$ MeV to approximately $450$ MeV and lattice spacing values as small as $0.06$fm. Our main result for the vector form factor at zero 4-momentum transfer is $f_+(0)=0.9683(65)$ where the uncertainty is both statistical and systematic. By combining our result with the experimental value of $f_+(0)|V_{us}|$ we obtain $|V_{us}|=0.2234(16)$, which satisfies the unitarity constraint of the Standard Model at the permille level.

  4. Executive Summary The Morgantown metropolitan statistical area (MSA) continued to expand in 2011, adding jobs

    E-Print Network [OSTI]

    Mohaghegh, Shahab

    job gains in natural resources and mining (new coal mine and continued development of the Marcellus. In addition, state and federal budgets are likely to tighten during the forecast, putting pressure on spending OF BUSINESS AND ECONOMIC RESEARCH COLLEGE OF BUSINESS AND ECONOMICS WEST VIRGINIA UNIVERSITY www

  5. (Draft) Community air pollution and mortality: Analysis of 1980 data from US metropolitan areas

    SciTech Connect (OSTI)

    Lipfert, F.W.

    1992-11-01T23:59:59.000Z

    1980 data from up to 149 metropolitan areas were used to define cross-sectional associations between community air pollution and ``excess`` human mortality. The regression model proposed by Ozkaynak and Thurston (1987), which accounted for age, race, education, poverty, and population density, was evaluated and several new models were developed. The new models also accounted for migration, drinking water hardness, and smoking, and included a more detailed description of race. Cause-of-death categories analyzed include all causes, all ``non-external`` causes, major cardiovascular diseases, and chronic obstructive pulmonary diseases (COPD). Both annual mortality rates and their logarithms were analyzed. Air quality data were obtained from the EPA AIRS database (TSP, SO{sub 4}{sup =}, Mn, and ozone) and from the inhalable particulate network (PM{sub 15}, PM{sub 2.5} and SO{sub 4}{sup =}, for 63{sup 4} locations). The data on particulates were averaged across all monitoring stations available for each SMSA and the TSP data were restricted to the year 1980. The associations between mortality and air pollution were found to be dependent on the socioeconomic factors included in the models, the specific locations included in the data set, and the type of statistical model used. Statistically significant associations were found as follows: between TSP and mortality due to non-external causes with log-linear models, but not with a linear model betweenestimated 10-year average (1980--90) ozone levels and 1980 non-external and cardiovascular deaths; and between TSP and COPD mortality for both linear and log-linear models. When the sulfate contribution to TSP was subtracted, the relationship with COPD mortality was strengthened.

  6. (Draft) Community air pollution and mortality: Analysis of 1980 data from US metropolitan areas

    SciTech Connect (OSTI)

    Lipfert, F.W.

    1992-11-01T23:59:59.000Z

    1980 data from up to 149 metropolitan areas were used to define cross-sectional associations between community air pollution and excess'' human mortality. The regression model proposed by Ozkaynak and Thurston (1987), which accounted for age, race, education, poverty, and population density, was evaluated and several new models were developed. The new models also accounted for migration, drinking water hardness, and smoking, and included a more detailed description of race. Cause-of-death categories analyzed include all causes, all non-external'' causes, major cardiovascular diseases, and chronic obstructive pulmonary diseases (COPD). Both annual mortality rates and their logarithms were analyzed. Air quality data were obtained from the EPA AIRS database (TSP, SO[sub 4][sup =], Mn, and ozone) and from the inhalable particulate network (PM[sub 15], PM[sub 2.5] and SO[sub 4][sup =], for 63[sup 4] locations). The data on particulates were averaged across all monitoring stations available for each SMSA and the TSP data were restricted to the year 1980. The associations between mortality and air pollution were found to be dependent on the socioeconomic factors included in the models, the specific locations included in the data set, and the type of statistical model used. Statistically significant associations were found as follows: between TSP and mortality due to non-external causes with log-linear models, but not with a linear model betweenestimated 10-year average (1980--90) ozone levels and 1980 non-external and cardiovascular deaths; and between TSP and COPD mortality for both linear and log-linear models. When the sulfate contribution to TSP was subtracted, the relationship with COPD mortality was strengthened.

  7. Efficient detection of contagious outbreaks in massive metropolitan encounter networks

    E-Print Network [OSTI]

    Sun, Lijun; Lee, Der-Horng; Cebrian, Manuel

    2014-01-01T23:59:59.000Z

    Physical contact remains difficult to trace in large metropolitan networks, though it is a key vehicle for the transmission of contagious outbreaks. Co-presence encounters during daily transit use provide us with a city-scale time-resolved physical contact network, consisting of 1 billion contacts among 3 million transit users. Here, we study the advantage that knowledge of such co-presence structures may provide for early detection of contagious outbreaks. We first examine the "friend sensor" scheme --- a simple, but universal strategy requiring only local information --- and demonstrate that it provides significant early detection of simulated outbreaks. Taking advantage of the full network structure, we then identify advanced "global sensor sets", obtaining substantial early warning times savings over the friends sensor scheme. Individuals with highest number of encounters are the most efficient sensors, with performance comparable to individuals with the highest travel frequency, exploratory behavior and ...

  8. Term statistics Zipf's law text statistics

    E-Print Network [OSTI]

    Lu, Jianguo

    Term statistics Zipf's law text statistics October 20, 2014 text statistics 1 / 19 #12;Term statistics Zipf's law Overview 1 Term statistics 2 Zipf's law text statistics 2 / 19 #12;Term statistics Zipf's law Outline 1 Term statistics 2 Zipf's law text statistics 3 / 19 #12;Term statistics Zipf's law Model

  9. Unequal development : decentralization and fiscal disparities in the Metropolitan Zone of the Valley of Mexico

    E-Print Network [OSTI]

    Raich, Uri

    2006-01-01T23:59:59.000Z

    This study is about the impact of decentralization in metropolitan areas. Studies of fiscal decentralization have largely centered on the formal tiers of government, without looking at the effects of this process on the ...

  10. Impact of primary formaldehyde on air pollution in the Mexico City Metropolitan Area

    E-Print Network [OSTI]

    Lei, Wenfang

    Formaldehyde (HCHO) is a radical source that plays an important role in urban atmospheric chemistry and ozone formation. The Mexico City Metropolitan Area (MCMA) is characterized by high anthropogenic emissions of HCHO ...

  11. Chemical evolution of volatile organic compounds in the outflow of the Mexico City Metropolitan area

    E-Print Network [OSTI]

    2010-01-01T23:59:59.000Z

    and dispersion of a Mexico City pollution out- flow eventon air pollution in the Mexico City Metropolitan Area,pollution transport during the MILAGRO-2006 campaign: a case study of a major Mexico

  12. Planners and the Pork Barrel: Metropolitan Engagement in and Resistance to Congressional Transportation Earmarking

    E-Print Network [OSTI]

    Sciara, Gian-Claudia

    2009-01-01T23:59:59.000Z

    Tri-State Regional Planning Commission, which included metropolitan countiesCounty Department of Transportation Olivia Clark Executive Director of Governmental Affairs Tri-tri-state MPO in 1982, NYMTC has consisted of nine voting members, representing county

  13. Urban growth pattern and sustainable development: a comparative study of municipalities in the Seoul Metropolitan Region

    E-Print Network [OSTI]

    Paek, Seunggeun

    2006-10-30T23:59:59.000Z

    The main purpose of this study was to obtain a better understanding of the impact of urban growth and change on sustainability based on a comparative study of municipalities comprising Gyeonggi Province within the Seoul Metropolitan Region, Korea...

  14. Set of Comparable Carbon Footprints for Highway Travel in Metropolitan America

    SciTech Connect (OSTI)

    Southworth, Frank [ORNL; Sonnenberg, Anthon [Georgia Institute of Technology

    2011-01-01T23:59:59.000Z

    The authors describe the development of a set of carbon dioxide emissions estimates for highway travel by automobile, truck, bus and other public transit vehicle movements within the nation s 100 largest metropolitan areas, in calendar year 2005. Considerable variability is found to exist across metropolitan areas when these greenhouse gas emissions are measured on a per capita and a per gross metropolitan product (GMP) basis. Least square regression modeling shows a relationship between emissions per capita and per GMP with truck traffic share, transit share, employment density, population dispersion within the metro area, and GMP per capita. As a result many of the nation s largest metropolitan areas tend to have lower CO2 emissions per capita and per GMP than smaller and more recently developed metro areas.

  15. Economic impact of M.I.T. on Cambridge and Metropolitan Boston

    E-Print Network [OSTI]

    Finberg, Irving William

    1964-01-01T23:59:59.000Z

    This thesis investigated the economic impact of the Massachusetts Institute of Technology on its host city, Cambridge, and upon the Boston Metropolitan Area. The primary purpose was to develop sufficient information about ...

  16. Metropolitan governance and local land use planning in Boston, Denver, and Portland

    E-Print Network [OSTI]

    Rosan, Christina

    2007-01-01T23:59:59.000Z

    Metropolitan areas across the U.S. are characterized by sprawling development which uses larger amounts of open space than necessary, leads to the inefficient use of energy and water, increases social inequality, and causes ...

  17. The participation, spatial distribution, and consumption patterns of boaters residing in Metropolitan Toronto

    E-Print Network [OSTI]

    Weakley, John Robert James

    1971-01-01T23:59:59.000Z

    Board produced a conceptual plan for the redevelopment of the fifty miles of Lake Ontario shoreline within the Metropolitan Toronto Planning Area. Although the Plan provided for numerous marinas and boatramps, the Planning Board was hampered by a... to as the summer cottage is particularly well developed in Central Ontario (9). A large percentage of the boats licensed in Metropolitan Toronto are used in conjunction with these cottages (10). This porportionately high non-urban use of boats can be expected...

  18. Regional planning and operations architectures as means to foster transportation integration in the Mexico City Metropolitan Area

    E-Print Network [OSTI]

    Ortiz Mantilla, Bernardo Jose, 1977-

    2005-01-01T23:59:59.000Z

    The MCMA complexity in political, institutional, economical, and jurisdictional terms has resulted in limited coordination between MCMA authorities that in conjunction with the limited role of metropolitan transportation ...

  19. Porcine arterivirus activates the NF-{kappa}B pathway through I{kappa}B degradation

    SciTech Connect (OSTI)

    Lee, Sang-Myeong [Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri-Columbia, MO 65211 (United States); Kleiboeker, Steven B. [Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri-Columbia, MO 65211 (United States) and Veterinary Medical Diagnostic Laboratory, College of Veterinary Medicine, University of Missouri-Columbia, MO 65211 (United States)]. E-mail: KleiboekerS@Missouri.edu

    2005-11-10T23:59:59.000Z

    Nuclear factor-kappaB (NF-{kappa}B) is a critical regulator of innate and adaptive immune function as well as cell proliferation and survival. The present study demonstrated for the first time that a virus belonging to the Arteriviridae family activates NF-{kappa}B in MARC-145 cells and alveolar macrophages. In porcine reproductive and respiratory syndrome virus (PRRSV)-infected cells, NF-{kappa}B activation was characterized by translocation of NF-{kappa}B from the cytoplasm to the nucleus, increased DNA binding activity, and NF-{kappa}B-regulated gene expression. NF-{kappa}B activation was increased as PRRSV infection progressed and in a viral dose-dependent manner. UV-inactivation of PRRSV significantly reduced the level of NF-{kappa}B activation. Degradation of I{kappa}B protein was detected late in PRRSV infection, and overexpression of the dominant negative form of I{kappa}B{alpha} (I{kappa}B{alpha}DN) significantly suppressed NF-{kappa}B activation induced by PRRSV. However, I{kappa}B{alpha}DN did not affect viral replication and viral cytopathic effect. PRRSV infection induced oxidative stress in cells by generating reactive oxygen species (ROS), and antioxidants inhibited NF-{kappa}B DNA binding activity in PRRSV-infected cells, suggesting ROS as a mechanism by which NF-{kappa}B was activated by PRRSV infection. Moreover, NF-{kappa}B-dependent expression of matrix metalloproteinase (MMP)-2 and MMP-9 was observed in PRRSV-infected cells, an observation which implies that NF-{kappa}B activation is a biologically significant aspect of PRRSV pathogenesis. The results presented here provide a basis for understanding molecular pathways of pathology and immune evasion associated with disease caused by PRRSV.

  20. Smoothing single-crystalline SiC surfaces by reactive ion etching using pure NF{sub 3} and NF{sub 3}/Ar mixture gas plasmas

    SciTech Connect (OSTI)

    Tasaka, Akimasa, E-mail: aki-tasaka-load@yahoo.co.jp [Department of Molecular Chemistry and Biochemistry, Faculty of Science and Engineering, Doshisha University, 1-3 Miyako-dani, Tatara, Kyotanabe, Kyoto 610-0321, Japan and Department of Applied Chemistry, Graduate School of Engineering, Doshisha University, 1-3 Miyako-dani, Tatara, Kyotanabe, Kyoto 610-0321 (Japan); Kotaka, Yuki [Department of Applied Chemistry, Graduate School of Engineering, Doshisha University, 1-3 Miyako-dani, Tatara, Kyotanabe, Kyoto 610-0321 (Japan); Oda, Atsushi; Saito, Morihiro [Department of Molecular Chemistry and Biochemistry, Faculty of Science and Engineering, Doshisha University, 1-3 Miyako-dani, Tatara, Kyotanabe, Kyoto 610-0321 (Japan); Tojo, Tetsuro [Toyo Tanso Co, Ltd., 5-7-2 Takeshima, Nishi yodogawa-ku, Osaka 555-0011 (Japan); Inaba, Minoru [Department of Molecular Chemistry and Biochemistry, Faculty of Science and Engineering, Doshisha University, 1-3 Miyako-dani, Tatara, Kyotanabe, Kyoto 610-0321, Japan and Department of Applied Chemistry, Graduate School of Science and Engineering, Doshisha University, 1-3 Miyako-dani, Tatara, Kyotanabe, Kyoto 610-0321 (Japan)

    2014-09-01T23:59:59.000Z

    In pure NF{sub 3} plasma, the etching rates of four kinds of single-crystalline SiC wafer etched at NF{sub 3} pressure of 2?Pa were the highest and it decreased with an increase in NF{sub 3} pressure. On the other hand, they increased with an increase in radio frequency (RF) power and were the highest at RF power of 200?W. A smooth surface was obtained on the single-crystalline 4H-SiC after reactive ion etching at NF{sub 3}/Ar gas pressure of 2?Pa and addition of Ar to NF{sub 3} plasma increased the smoothness of SiC surface. Scanning electron microscopy observation revealed that the number of pillars decreased with an increase in the Ar-concentration in the NF{sub 3}/Ar mixture gas. The roughness factor (R{sub a}) values were decreased from 51.5?nm to 25.5?nm for the As-cut SiC, from 0.25?nm to 0.20?nm for the Epi-SiC, from 5.0?nm to 0.7?nm for the Si-face mirror-polished SiC, and from 0.20?nm to 0.16?nm for the C-face mirror-polished SiC by adding 60% Ar to the NF{sub 3} gas. Both the R{sub a} values of the Epi- and the C-face mirror-polished wafer surfaces etched using the NF{sub 3}/Ar (40:60) plasma were similar to that treated with mirror polishing, so-called the Catalyst-Referred Etching (CARE) method, with which the lowest roughness of surface was obtained among the chemical mirror polishing methods. Etching duration for smoothing the single-crystalline SiC surface using its treatment was one third of that with the CARE method.

  1. 1 Managed by UT-Battelle for the U.S. Department of Energy NF Splash Mitigation 12 July 2011

    E-Print Network [OSTI]

    McDonald, Kirk

    1 Managed by UT-Battelle for the U.S. Department of Energy NF Splash Mitigation 12 July 2011 by UT-Battelle for the U.S. Department of Energy NF Splash Mitigation 12 July 2011 Splash Mitigation for comparison & final determination #12;3 Managed by UT-Battelle for the U.S. Department of Energy NF Splash

  2. Four Faculty Positions Applied Statistics & Computational Statistics

    E-Print Network [OSTI]

    Shepp, Larry

    Four Faculty Positions Applied Statistics & Computational Statistics The Department of Statistics at the Assistant Professor rank. Two positions are open in the area of Applied Statistics, with a focus on the development of statistical methodology and statistical consulting. The other two positions are open

  3. DraftApril 7, 2009 Features of Climate-Smart Metropolitan Economies

    E-Print Network [OSTI]

    Draft­April 7, 2009 Chapter 8 Features of Climate-Smart Metropolitan Economies Marilyn A. Brown-carbon climate-smart leadership that is required to meet the nation's targets and timetables necessary to avoid emissions of carbon dioxide.) Residential and commercial buildings account for 39 percent of the carbon

  4. Computer Lab Software Installation Policy for the Metropolitan Instructional Support Laboratory

    E-Print Network [OSTI]

    Computer Lab Software Installation Policy for the Metropolitan Instructional Support Laboratory Laboratory (MISL) provides computer lab space for faculty, staff and student use as individuals or in classes on lab computers. This policy applies to both stationary and portable lab computers. Policy: Scenario 1

  5. ERASMUS 2011-2012. . Manchester Metropolitan University UK MANCHES 04 3 18

    E-Print Network [OSTI]

    Kouroupetroglou, Georgios

    ERASMUS 2011-2012. . . / . Manchester Metropolitan University UK MANCHES 04 3 18 PORTO 02 2 20 . University of Presov SK PRESOV 01 2 8 . Hacettepe University TR ANKARA 03 2 10 . University of Eastern Finland SF KUOPIO 12 4 18 Universitat fur Bodenkulrur Wien (BOKU) A WIEN 03 3 18

  6. ERASMUS 2011-2012. . Manchester Metropolitan University UK MANCHES 04 3 18

    E-Print Network [OSTI]

    Kouroupetroglou, Georgios

    ERASMUS 2011-2012. 1 . Manchester Metropolitan University UK MANCHES 04 3 18 PORTO 02 2 20 . University of Presov SK PRESOV 01 2 8 . Hacettepe University TR ANKARA 03 2 10 . University of Eastern Finland SF KUOPIO 12 4 18 Universitat fur Bodenkulrur Wien (BOKU) A WIEN 03 3 18

  7. BNY Mellon -Leading the way across the globe Manchester Metropolitan University

    E-Print Network [OSTI]

    BNY Mellon - Leading the way across the globe Manchester Metropolitan University 2012 #12;Page 2 business Established The Bank of New York Securities Co. Japan, Ltd. Established BNY Luxembourg Acquired) Luxembourg A radical increase in product breadth and global reach Early adopters of mainframe technology 1900

  8. Conservation justice in metropolitan Cape Town: A study at the Macassar Dunes Conservation Area

    E-Print Network [OSTI]

    Silander Jr., John A.

    Stakeholder analysis a b s t r a c t Conservation justice, a concept analogous to environmental justiceConservation justice in metropolitan Cape Town: A study at the Macassar Dunes Conservation Area J xxxx Keywords: Conservation justice Community-based conservation South Africa Urban conservation

  9. The Transportation Energy and Carbon Footprints of the 100 Largest U.S. Metropolitan Areas

    SciTech Connect (OSTI)

    Southworth, Frank [ORNL; Sonnenberg, Anthon [Georgia Institute of Technology; Brown, Marilyn A [ORNL

    2008-01-01T23:59:59.000Z

    We present estimates of the automobile and truck travel based energy and carbon footprints of the largest 100 U.S. metropolitan areas. The footprints are based on the estimated vehicle miles traveled and the transportation fuels consumed. Results are presented on an annual basis and represent end use emissions only. Total carbon emissions, emissions per capita, and emissions per dollar of gross metropolitan product are reported. Two years of annual data were examined, 2000 and 2005, with most of the in-depth analysis focused on the 2005 results. In section 2 we provide background data on the national picture and derive some carbon and energy consumption figures for the nation as a whole. In section 3 of the paper we examine the metropolitan area-wide results based on the sums and averages across all 100 metro areas, and compare these with the national totals and averages. In section 4 we present metropolitan area specific footprints and examine the considerable variation that is found to exist across individual metro areas. In doing so we pay particular attention to the effects that urban form might have on these differences. Finally, section 5 provides a summary of major findings, and a list of caveats that need to be borne in mind when using the results due to known limitations in the data sources used.

  10. Statistical Sciences

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What'sis Taking Over Our Instagram Secretary900 SpecialNanoparticulateEmissions Targetson6 Statistical

  11. IKK{epsilon} modulates RSV-induced NF-{kappa}B-dependent gene transcription

    SciTech Connect (OSTI)

    Bao Xiaoyong; Indukuri, Hemalatha; Liu Tianshuang; Liao Suiling [Department of Pediatrics, University of Texas Medical Branch, Galveston, TX (United States); Tian, Bing; Brasier, Allan R. [Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX (United States); Garofalo, Roberto P. [Department of Pediatrics, University of Texas Medical Branch, Galveston, TX (United States); Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX (United States); Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, TX (United States); Casola, Antonella, E-mail: ancasola@utmb.ed [Department of Pediatrics, University of Texas Medical Branch, Galveston, TX (United States); Department of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX (United States); Sealy Center for Vaccine Development, University of Texas Medical Branch, Galveston, TX (United States)

    2010-12-20T23:59:59.000Z

    Respiratory syncytial virus (RSV), a negative-strand RNA virus, is the most common cause of epidemic respiratory disease in infants and young children. RSV infection of airway epithelial cells induces the expression of immune/inflammatory genes through the activation of a subset of transcription factors, including Nuclear Factor-{kappa}B (NF-{kappa}B). In this study we have investigated the role of the non canonical I{kappa}B kinase (IKK){epsilon} in modulating RSV-induced NF-{kappa}B activation. Our results show that inhibition of IKK{epsilon} activation results in significant impairment of viral-induced NF-{kappa}B-dependent gene expression, through a reduction in NF-{kappa}B transcriptional activity, without changes in nuclear translocation or DNA-binding activity. Absence of IKK{epsilon} results in a significant decrease of RSV-induced NF-{kappa}B phosphorylation on serine 536, a post-translational modification important for RSV-induced NF-{kappa}B-dependent gene expression, known to regulate NF-{kappa}B transcriptional activity without affecting nuclear translocation. This study identifies a novel mechanism by which IKK{epsilon} regulates viral-induced cellular signaling.

  12. Community air pollution and mortality: Analysis of 1980 data from US metropolitan areas. 1: Particulate air pollution

    SciTech Connect (OSTI)

    Lipfert, F.W.

    1992-11-01T23:59:59.000Z

    1980 data from up to 149 metropolitan areas were used to define cross-sectional associations between community air pollution and excess human mortality. The regression model proposed by Oezkaynak and Thurston, which accounted for age, race, education, poverty, and population density, was evaluated and several new models were developed. The new models also accounted for population change, drinking water hardness, and smoking, and included a more detailed description of race. Cause-of-death categories analyzed include all causes, all non-external causes, major cardiovascular diseases, and chronic obstructive pulmonary diseases (COPD). Both annual mortality rates and their logarithms were analyzed. The data on particulates were averaged across all monitoring stations available for each SMSA and the TSP data were restricted to the year 1980. The associations between mortality and air pollution were found to be dependent on the socioeconomic factors included in the models, the specific locations included din the data set, and the type of statistical model used. Statistically significant associations were found between TSP and mortality due to non-external causes with log-linear models, but not with a linear model, and between TS and COPD mortality for both linear and log-linear models. When the sulfate contribution to TSP was subtracted, the relationship with COPD mortality was strengthened. Scatter plots and quintile analyses suggested a TSP threshold for COPD mortality at around 65 ug/m{sup 3} (annual average). SO{sub 4}{sup {minus}2}, Mn, PM{sup 15}, and PM{sub 2.5} were not significantly associated with mortality using the new models.

  13. Spike statistics

    E-Print Network [OSTI]

    J. Mark Heinzle; Claes Uggla

    2012-12-21T23:59:59.000Z

    In this paper we explore stochastical and statistical properties of so-called recurring spike induced Kasner sequences. Such sequences arise in recurring spike formation, which is needed together with the more familiar BKL scenario to yield a complete description of generic spacelike singularities. In particular we derive a probability distribution for recurring spike induced Kasner sequences, complementing similar available BKL results, which makes comparisons possible. As examples of applications, we derive results for so-called large and small curvature phases and the Hubble-normalized Weyl scalar.

  14. Homeostatic control of IkappaB metabolism determines NF- kappaB responsiveness

    E-Print Network [OSTI]

    O'Dea, Ellen Louise

    2010-01-01T23:59:59.000Z

    19-26. O'Dea, E. and Hoffmann, A. 2009. NF-kappaB signaling.J.D. , Levchenko, A. , and Hoffmann, A. 2007. A homeostaticS.L. , Cheng, C. , and Hoffmann, A. 2007. A temporal code

  15. Response and Resistance to NF-?B Inhibitors in Mouse Models of Lung Adenocarcinoma

    E-Print Network [OSTI]

    Xue, Wen

    Lung adenocarcinoma is a leading cause of cancer death worldwide. We recently showed that genetic inhibition of the NF-?B pathway affects both the initiation and the maintenance of lung cancer, identifying this pathway as ...

  16. Requirement for NF-?B signalling in a mouse model of lung adenocarcinoma

    E-Print Network [OSTI]

    Meylan, Etienne

    NF-?B transcription factors function as crucial regulators of inflammatory and immune responses as well as of cell survival. They have also been implicated in cellular transformation and tumorigenesis. However, despite ...

  17. Modeling urban growth and land use/land cover change in the Houston Metropolitan Area from 2002 - 2030

    E-Print Network [OSTI]

    Oguz, Hakan

    2005-08-29T23:59:59.000Z

    spatially explicit cellular automata model, to simulate future (2002-2030) urban growth in the Houston metropolitan area, one of the fastest growing metropolises in the United States during the past decades. The model is calibrated with historical data...

  18. The case for pension plan and university endowment equity investment in brownfields in the urban core of major metropolitan areas

    E-Print Network [OSTI]

    Larsen, Tamara C. (Tamara Candace), 1977-

    2003-01-01T23:59:59.000Z

    The purpose of this thesis is to present a case for institutional equity investment in brownfields in the urban core of major metropolitan areas. Pension plans and university endowments are the primary institutional investors ...

  19. The effectiveness of jobs-housing balance as a strategy for reducing traffic congestion: a study of metropolitan Bangkok 

    E-Print Network [OSTI]

    Lobyaem, Sonchai

    2006-10-30T23:59:59.000Z

    Bangkok is widely known for its severe traffic congestion. The Thai government advocates the concept of jobs and housing balance (JHB) as a strategy for reducing traffic congestion in Metropolitan Bangkok. The basic idea ...

  20. The effectiveness of jobs-housing balance as a strategy for reducing traffic congestion: a study of metropolitan Bangkok

    E-Print Network [OSTI]

    Lobyaem, Sonchai

    2006-10-30T23:59:59.000Z

    Bangkok is widely known for its severe traffic congestion. The Thai government advocates the concept of jobs and housing balance (JHB) as a strategy for reducing traffic congestion in Metropolitan Bangkok. The basic idea is to decentralize the jobs...

  1. In situ measurements of speciated atmospheric mercury and the identification of source regions in the Mexico City Metropolitan Area

    E-Print Network [OSTI]

    Rutter, A. P.

    In order to expand the currently limited understanding of atmospheric mercury source-receptor relationships in the Mexico City Metropolitan Area, real time measurements of atmospheric mercury were made at a downtown urban ...

  2. Generalizations of quantum statistics

    E-Print Network [OSTI]

    O. W. Greenberg

    2008-05-02T23:59:59.000Z

    We review generalizations of quantum statistics, including parabose, parafermi, and quon statistics, but not including anyon statistics, which is special to two dimensions.

  3. A test of first order scaling in Nf=2 QCD

    E-Print Network [OSTI]

    G. Cossu; M. D'Elia; A. Di Giacomo; C. Pica

    2007-09-30T23:59:59.000Z

    We complete our analysis of Nf=2 QCD based on the lattice staggered fermion formulation. Using a series of Monte Carlo simulations at fixed (amq*Ls^yh) one is able to test the universality class with given critical exponent yh. This strategy has been used to test the O(4) universality class and it has been presented at the previous Lattice conferences. No agreement was found with simulations in the mass range amq=[0.01335,0.15] using lattices with Ls=16 up to 32 and Lt=4. With the same strategy, we now investigate the possibility of a first order transition using a new set of Monte Carlo data corresponding to yh=3 in the same mass and volume range as the one used for O(4). A substantial agreement is observed both in the specific heat scaling and in the scaling of the chiral condensate, while the chiral susceptibilities still presents visible deviation from scaling in the mass range explored.

  4. Sci. Aging Knowl. Environ., Vol. 2004, Issue 34, pp. nf78, 25 August 2004 [DOI: 10.1126/sageke.2004.34.nf78

    E-Print Network [OSTI]

    Seroude, Laurent

    : They scrubbed fly eggs with alcohol, fed the animals irradiated food, and kept them in sterile containers: http://sageke.sciencemag.org/cgi/content/full/2004/34/nf78 Nasty germs in fast-food burgers can kill direction--from fare that included antibiotics to "dirty" food--extended fly life on day 2 but not on day 4

  5. FISHERY STATISTICS UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES 1972 STATISTICAL DIGEST NO. 66 Prepared by STATISTICS;ACKNOWLEDGMENTS The data in this edition of "Fishery Statistics of the United States" were collected in co- operation with the various States and tabulated by the staff of the Statistics and Market News Division

  6. NF-?B1 Inhibits TLR-Induced IFN-? Production in Macrophages Through TPL-2-dependent ERK Activation

    E-Print Network [OSTI]

    Yang, Huei-Ting

    Although NF-?B1 p50/p105 has critical roles in immunity, the mechanism by which NF-?B1 regulates inflammatory responses is unclear. In this study, we analyzed the gene expression profile of LPS-stimulated Nfkb1?/? macrophages ...

  7. XIAP and cIAP1 amplifications induce Beclin 1-dependent autophagy through NF?B activation

    E-Print Network [OSTI]

    Lin, Fang; Ghislat, Ghita; Luo, Shouqing; Renna, Maurizio; Siddiqi, Farah; Rubinsztein, David C.

    2015-02-10T23:59:59.000Z

    ). In both steady state and stimulated conditions with TGF? that activates NF?B through TAK1 (33), nei- ther the overexpression of XIAP nor its knockdown affected the transcriptional activation of the NF?B promoter (Fig. 3B, top). The effect of TGF?...

  8. Regulation Of Nf=kb And Mnsod In Low Dose Radiation Induced Adaptive Protection Of Mouse And Human Skin Cells

    SciTech Connect (OSTI)

    Jian Li

    2012-11-07T23:59:59.000Z

    A sampling of publications resulting from this grant is provided. One is on the subject of NF-κB-Mediated HER2 Overexpression in Radiation-Adaptive Resistance. Another is on NF-κB-mediated adaptive resistance to ionizing radiation.

  9. Instruction sheet for the consolidation of the standard NF EN 693 dated September 2001 and its amendment A1 Machine tools : Safety : Hydraulic presses

    E-Print Network [OSTI]

    Association Française de Normalisation. Paris

    2009-01-01T23:59:59.000Z

    Instruction sheet for the consolidation of the standard NF EN 693 dated September 2001 and its amendment A1

  10. 1 Managed by UT-Battelle for the U.S. Department of Energy NF-IDS Videoconference 2 Jun 2009

    E-Print Network [OSTI]

    McDonald, Kirk

    1 Managed by UT-Battelle for the U.S. Department of Energy NF-IDS Videoconference 2 Jun 2009 by UT-Battelle for the U.S. Department of Energy NF-IDS Videoconference 2 Jun 2009 Purpose · Compare · Compilation of magnet geometry data #12;3 Managed by UT-Battelle for the U.S. Department of Energy NF

  11. Introduction The NF-B/Rel family of transcription factors is composed of

    E-Print Network [OSTI]

    Arnold, Jonathan

    gene expression exhibited a requirement for the host IKK complex. A detailed kinetic analysis of NF- B expression of anti-apoptotic genes and prevent death of infected cells in order to allow replication in a loss of the anti-apoptotic phenotype and a decrease in pro-survival gene expression (Molestina et al

  12. Single-cell NF-kB dynamics reveal digital activation and analogue information processing

    E-Print Network [OSTI]

    Quake, Stephen R.

    LETTERS Single-cell NF-kB dynamics reveal digital activation and analogue information processing and is a digital process at the single-cell level with fewer cells responding at lower doses. Cells also encode that reproduces both the digital and analogue dynamics as well as most gene expression profiles at all measured

  13. Microstructural Evolution in Two Variants of NF709 at 1023 and 1073 K

    E-Print Network [OSTI]

    Cambridge, University of

    and that could invalidate the extrapolations of short-term creep test data, and to identify any precipitates.K.D.H. BHADESHIA The microstructural state of two grades of the creep-resistant austenitic stainless steels NF709 regarded as one of the best austenitic steels for elevated temperature applications because of its creep

  14. Coal dust contiguity-induced changes in the concentration of TNF- and NF- B p65 on the ocular surface

    SciTech Connect (OSTI)

    Sun, Z.Y.; Hong, J.; Liu, Z.Y.; Jin, X.D.; Gu, C.H. [China Medical University, Shenyang (China)

    2009-07-01T23:59:59.000Z

    To observe the influence of coal dust on ocular surface of coal miners and rabbits with coal dust contiguity on expression TNF- and NF- Bp65 and dry eye occurrence. Expression TNF- and NF- Bp65 in ocular surface were determined. Results showed tear production, BUT and lysozyme decreased for coal miners and rabbits with coal dust contiguity. Coal dust exposure was linked to development of xerophthalmia, and induced a higher expression of NF- B p65 and TNF- perhaps as a mechanism to resist coal dust ocular surface injury.

  15. Statistical Language Modelling 

    E-Print Network [OSTI]

    Gotoh, Yoshihiko; Renals, Steve

    2003-01-01T23:59:59.000Z

    the underlying models from large amounts of data. Importantly, such statistical approaches often produce useful results. Statistical approaches seem especially well-suited to spoken language which is often spontaneous or conversational and not readily amenable...

  16. Interpreting Accident Statistics

    E-Print Network [OSTI]

    Ferreira, Joseph Jr.

    Accident statistics have often been used to support the argument that an abnormally small proportion of drivers account for a large proportion of the accidents. This paper compares statistics developed from six-year data ...

  17. Statistics 36-756: Advanced Statistics II Syllabus: Fall, 2006

    E-Print Network [OSTI]

    Fienberg, Stephen E.

    , Journal of the American Statistical Association, Journal of the Royal Statistical Society, StatisticalStatistics 36-756: Advanced Statistics II Syllabus: Fall, 2006 Instructor: Stephen E. Fienberg 132G: · To consider major topics from statistical theory and the foundations of inference not covered in Statistics 36

  18. Statistics Statistique Canada Canada

    E-Print Network [OSTI]

    Sinnamon, Gordon J.

    Statistics Statistique Canada Canada Human Resources and Ressources humaines et Skills Development Canada Développement des compétences Canada Culture,Tourism and the Centre for Education Statistics about this product or the wide range of services and data available from Statistics Canada, visit our

  19. STATISTICAL COMPUTING AND GRAPHICS

    E-Print Network [OSTI]

    Masci, Frank

    Marron for a helpful comment. @ 1997 American Statistical Association bin width should be chosen soSTATISTICAL COMPUTING AND GRAPHICS Data-Based Choice of Histogram Bin Width The most important of the "optimal" bin width. Default bin widths in most common statistical packages are, at least for large samples

  20. Omentin inhibits TNF-{alpha}-induced expression of adhesion molecules in endothelial cells via ERK/NF-{kappa}B pathway

    SciTech Connect (OSTI)

    Zhong, Xia, E-mail: zhongxia1977@126.com [Department of Emergency, Provincial Hospital Affiliated to Shandong University, Jinan 250021 (China)] [Department of Emergency, Provincial Hospital Affiliated to Shandong University, Jinan 250021 (China); Li, Xiaonan; Liu, Fuli; Tan, Hui [Department of Emergency, Provincial Hospital Affiliated to Shandong University, Jinan 250021 (China)] [Department of Emergency, Provincial Hospital Affiliated to Shandong University, Jinan 250021 (China); Shang, Deya, E-mail: wenhuashenghuo1@163.com [Department of Emergency, Provincial Hospital Affiliated to Shandong University, Jinan 250021 (China)] [Department of Emergency, Provincial Hospital Affiliated to Shandong University, Jinan 250021 (China)

    2012-08-24T23:59:59.000Z

    Highlights: Black-Right-Pointing-Pointer Omentin inhibited TNF-{alpha}-induced adhesion of THP-1 cells to HUVECs. Black-Right-Pointing-Pointer Omentin reduces expression of ICAM-1 and VCAM-1 induced by TNF-{alpha} in HUVECs. Black-Right-Pointing-Pointer Omentin inhibits TNF-{alpha}-induced ERK and NF-{kappa}B activation in HUVECs. Black-Right-Pointing-Pointer Omentin supreeses TNF-{alpha}-induced expression of ICAM-1 and VCAM-1 via ERK/NF-{kappa}B pathway. -- Abstract: In the present study, we investigated whether omentin affected the expression of intracellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) in tumor necrosis factor-{alpha} (TNF-{alpha}) induced human umbilical vein endothelial cells (HUVECs). Our data showed that omentin decreased TNF-{alpha}-induced expression of ICAM-1 and VCAM-1 in HUVECs. In addition, omentin inhibited TNF-{alpha}-induced adhesion of THP-1 cells to HUVECs. Further, we found that omentin inhibited TNF-{alpha}-activated signal pathway of nuclear factor-{kappa}B (NF-{kappa}B) by preventing NF-{kappa}B inhibitory protein (I{kappa}B{alpha}) degradation and NF-{kappa}B/DNA binding activity. Omentin pretreatment significantly inhibited TNF-{alpha}-induced ERK activity and ERK phosphorylation in HUVECs. Pretreatment with PD98059 suppressed TNF-{alpha}-induced NF-{kappa}B activity. Omentin, NF-kB inhibitor (BAY11-7082) and ERK inhibitor (PD98059) reduced the up-regulation of ICAM-1 and VCAM-1 induced by TNF-{alpha}. These results suggest that omentin may inhibit TNF-{alpha}-induced expression of adhesion molecules in endothelial cells via blocking ERK/NF-{kappa}B pathway.

  1. Statistical Convergence and Convergence in Statistics

    E-Print Network [OSTI]

    Mark Burgin; Oktay Duman

    2006-12-07T23:59:59.000Z

    Statistical convergence was introduced in connection with problems of series summation. The main idea of the statistical convergence of a sequence l is that the majority of elements from l converge and we do not care what is going on with other elements. We show (Section 2) that being mathematically formalized the concept of statistical convergence is directly connected to convergence of such statistical characteristics as the mean and standard deviation. At the same time, it known that sequences that come from real life sources, such as measurement and computation, do not allow, in a general case, to test whether they converge or statistically converge in the strict mathematical sense. To overcome limitations induced by vagueness and uncertainty of real life data, neoclassical analysis has been developed. It extends the scope and results of the classical mathematical analysis by applying fuzzy logic to conventional mathematical objects, such as functions, sequences, and series. The goal of this work is the further development of neoclassical analysis. This allows us to reflect and model vagueness and uncertainty of our knowledge, which results from imprecision of measurement and inaccuracy of computation. In the context on the theory of fuzzy limits, we develop the structure of statistical fuzzy convergence and study its properties.

  2. $Re(A_0)$, $Re(A_2)$ and RG evolution for $N_f=3$

    E-Print Network [OSTI]

    Choi, K; Choi, Keunsu; Lee, Weonjong

    2005-01-01T23:59:59.000Z

    We present results of $Re (A_0)$ and $Re (A_2)$ calculated using HYP staggered fermions on the lattice of $16^3 \\times 64$ at $\\beta=6.0$. These results are obtained using leading order chiral perturbation in quenched QCD. Buras's original RG evolution matrix develops a removable singularity for $N_f=3$. This subtlety is resolved by finding a finite solution to RG equation and the results are presented.

  3. Agreement Execution Process Study: CRADAs and NF-WFO Agreements and the Speed of Business

    SciTech Connect (OSTI)

    Harrer, Bruce J.; Cejka, Cheryl L.; Macklin, Richard; Miksovic, Ann

    2011-02-01T23:59:59.000Z

    This report summarizes the findings of a study on the execution of Cooperative Research and Development Agreements (CRADAs) and Non-Federal Work for Others (NF-WFO) agreements across the U.S. Department of Energy (DOE) laboratory complex. The study provides quantitiative estimates of times required to negotiate and execute these agreements across the DOE complex. It identifies factors impacting on cycle times and describes best practicies used at various laboratories and site offices that reduce cycle times.

  4. Using a Regional Chemical Transport Model for the Analysis of Gaseous and Particulate Air Pollutants in the Mexico City Metropolitan Area

    E-Print Network [OSTI]

    Ali, Sajjad Ghulam

    2012-02-14T23:59:59.000Z

    Air quality in the Mexico City Metropolitan Area (MCMA) is the subject of many studies due to concerns from high emissions and their adverse effects on public health and the environment. In this study, a high resolution simulation is performed...

  5. The value trees contribute to residential property in the Austin metropolitan area: a factor in assessing the impact of oak wilt

    E-Print Network [OSTI]

    Martin, Clay Whitney

    1986-01-01T23:59:59.000Z

    THE VALUE TREES CONTRIBUTE TO RESIDENTIAL PROPERTY IN THE AUSTIN METROPOLITAN AREA: A FACTOR IN ASSESSING THE IMPACT OF OAK WILT A Thesis by CLAY WHITNEY MARTIN Submitted to the Graduate College of Texas A&M University in partial fulfillment... of the requirements for the degree of MASTER OF SCIENCE December 1986 Major Subject: Forestry THE VALUE TREES CONTRIBUTE TO RESIDENTIAL PROPERTY IN THE AUSTIN METROPOLITAN AREA: A FACTOR IN ASSESSING THE IMPACT OF OAK WILT A Thesis by CLAY WHITNEY MARTIN...

  6. BS in STATISTICS: Statistical Science Emphasis (695220) MAP Sheet Department of Statistics

    E-Print Network [OSTI]

    Olsen Jr., Dan R.

    BS in STATISTICS: Statistical Science Emphasis (695220) MAP Sheet Department of Statistics the following: Stat 121 Principles of Statistics Stat 151 Introduction to Bayesian Statistics Stat 201 Statistics for Engineers & Scientists Stat 301 Statistics & Probability for Sec Ed Note: Students who have

  7. Statistics 221 Statistical Computing Methods Instructor: Mark Irwin

    E-Print Network [OSTI]

    Irwin, Mark E.

    Linear algebra, Statistics 111, and knowledge of a computer programming language. Statistics 220 (1988). Elements of Statistical Computing: Numerical Computation. CRC Press. Splus / R: Venables WNStatistics 221 ­ Statistical Computing Methods Instructor: Mark Irwin Office: Science Center 235

  8. 1 Statistics Statistics plays an important role throughout society, providing

    E-Print Network [OSTI]

    Vertes, Akos

    1 Statistics STATISTICS Statistics plays an important role throughout society, providing data. They also explore how those skills can be applied to develop new initiatives. Statistics is one. UNDERGRADUATE Bachelor's program · Bachelor of Science with a major in statistics (http:// bulletin.gwu.edu/arts-sciences/statistics

  9. Practical Statistical Thinking Probability: The Language of Statistics

    E-Print Network [OSTI]

    Practical Statistical Thinking Probability: The Language of Statistics Essentials of Statistics and Probability Dhruv Sharma May 22, 2007 Department of Statistics, NC State University dbsharma@ncsu.edu SAMSI Undergrad Workshop Dhruv Sharma Essentials of Statistics and Probability #12;Practical Statistical Thinking

  10. Edinburgh Research Explorer Statistical Constraints

    E-Print Network [OSTI]

    Millar, Andrew J.

    Edinburgh Research Explorer Statistical Constraints Citation for published version: Rossi, R that links statistics and constraint programming. We dis- cuss two novel statistical constraints and some, Prestwich, S & Tarim, SA 2014, 'Statistical Constraints' Paper presented at 21st biennial European

  11. Part I STATISTICAL PHYSICS 1 Statistical Physics

    E-Print Network [OSTI]

    unknown authors

    In this first part of the book we shall study aspects of classical statistical physics that every physicist should know, but are not usually treated in elementary thermodynamics courses. Our study will lay the microphysical (particle-scale) foundations for the continuum physics of Parts II—VI. As a central feature of our approach, we shall emphasize the intimate connections between the relativistic formulation of statistical physics and its nonrelativistic limit, and between quantum statistical physics and the classical theory. Throughout, we shall presume that the reader is familiar with elementary thermodynamics, but not with other aspects of statistical physics. In Chap. 2 we will study kinetic theory — the simplest of all formalisms for analyzing systems of huge numbers of particles (e.g., molecules of air, or neutrons diffusing through a nuclear reactor, or photons produced in the big-bang origin of the Universe). In kinetic theory the key concept is the “distribution function ” or “number density of particles in phase space”, N; i.e., the number of particles per unit 3-dimensional volume of ordinary space and per unit 3-dimensional volume of momentum space. Despite first appearances, N turns out to be a geometric, frame-independent entity. This N and the frame-independent laws it

  12. Part I STATISTICAL PHYSICS 1 Statistical Physics

    E-Print Network [OSTI]

    unknown authors

    2004-01-01T23:59:59.000Z

    In this first part of the book we shall study aspects of classical statistical physics that every physicist should know, but are not usually treated in elementary thermodynamics courses. Our study will lay the microphysical (particle-scale) foundations for the continuum physics of Parts II—VI. As a central feature of our approach, we shall emphasize the intimate connections between the relativistic formulation of statistical physics and its nonrelativistic limit, and between quantum statistical physics and the classical theory. Throughout, we shall presume that the reader is familiar with elementary thermodynamics, but not with other aspects of statistical physics. In Chap. 2 we will study kinetic theory — the simplest of all formalisms for analyzing systems of huge numbers of particles (e.g., molecules of air, or neutrons diffusing through a nuclear reactor, or photons produced in the big-bang origin of the Universe). In kinetic theory the key concept is the “distribution function ” or “number density of particles in phase space”, N; i.e., the number of particles per unit 3-dimensional volume of ordinary space and per unit 3-dimensional volume of momentum space. Despite first appearances, N turns out to be a geometric, frame-independent entity. This N and the frame-independent laws it

  13. Part I STATISTICAL PHYSICS 1 Statistical Physics

    E-Print Network [OSTI]

    unknown authors

    In this first part of the book we shall study aspects of classical statistical physics that every physicist should know but are not usually treated in elementary thermodynamics courses. This study will lay the microphysical (particle-scale) foundations for the continuum physics of Parts II—VI. Throughout, we shall presume that the reader is familiar with elementary thermodynamics, but not with other aspects of statistical physics. As a central feature of our approach, we shall emphasize the intimate connections between the relativistic formulation of statistical physics and its nonrelativistic limit, and between quantum statistical physics and the classical theory. Chapter 2 will deal with kinetic theory, which is the simplest of all formalisms for studying systems of huge numbers of particles (e.g., molecules of air, or neutrons diffusing through a nuclear reactor, or photons produced in the big-bang origin of the Universe). In kinetic theory the key concept is the “distribution function ” or “number density of particles in phase space”, N; i.e., the number of particles per unit 3-dimensional volume of ordinary space and per unit 3-dimensional volume of momentum space. Despite first appearances, N turns out to be a geometric, frame-independent entity. This N and the laws it obeys provide

  14. R for Statistics Rafal Kulik

    E-Print Network [OSTI]

    Kulik, Rafal

    R for Statistics Rafal Kulik Department of Mathematics and Statistics University of Ottawa Statistical Society of Ottawa 23 September 2011 Rafal Kulik #12;R for Statistics SSO meeting Plan Rafal Kulik 1 #12;R for Statistics SSO meeting Plan What is R? Rafal Kulik 1 #12;R for Statistics SSO meeting

  15. Stellar Evolution A Statistical Model

    E-Print Network [OSTI]

    van Dyk, David

    Stellar Evolution A Statistical Model Statistical Computation Analysis of the Hyades Cluster Statistical Analysis of Stellar Evolution David A. van Dyk1 Steven DeGennaro2 Nathan Stein2 William H Statistical Analysis of Stellar Evolution #12;Stellar Evolution A Statistical Model Statistical Computation

  16. Weakly sufficient quantum statistics

    E-Print Network [OSTI]

    Katarzyna Lubnauer; Andrzej ?uczak; Hanna Pods?dkowska

    2009-11-23T23:59:59.000Z

    Some aspects of weak sufficiency of quantum statistics are investigated. In particular, we give necessary and sufficient conditions for the existence of a weakly sufficient statistic for a given family of vector states, investigate the problem of its minimality, and find the relation between weak sufficiency and other notions of sufficiency employed so far.

  17. Statistical laws in linguistics

    E-Print Network [OSTI]

    Altmann, Eduardo G

    2015-01-01T23:59:59.000Z

    Zipf's law is just one out of many universal laws proposed to describe statistical regularities in language. Here we review and critically discuss how these laws can be statistically interpreted, fitted, and tested (falsified). The modern availability of large databases of written text allows for tests with an unprecedent statistical accuracy and also a characterization of the fluctuations around the typical behavior. We find that fluctuations are usually much larger than expected based on simplifying statistical assumptions (e.g., independence and lack of correlations between observations).These simplifications appear also in usual statistical tests so that the large fluctuations can be erroneously interpreted as a falsification of the law. Instead, here we argue that linguistic laws are only meaningful (falsifiable) if accompanied by a model for which the fluctuations can be computed (e.g., a generative model of the text). The large fluctuations we report show that the constraints imposed by linguistic laws...

  18. NF-{kappa}B suppresses HIF-1{alpha} response by competing for P300 binding

    SciTech Connect (OSTI)

    Mendonca, Daniela B.S., E-mail: daniela_mendonca@dentistry.unc.edu [Universidade Catolica de Brasilia, Pos-Graduacao em Ciencias Genomicas e Biotecnologia, SGAN Quadra 916, Av. W5 Norte, 70790-160 Brasilia, DF (Brazil); Bone Biology and Implant Therapy Laboratory, Department of Prosthodontics, University of North Carolina at Chapel Hill, 330 Brauer Hall, CB 7450, Chapel Hill, NC 27599 (United States); Mendonca, Gustavo [Universidade Catolica de Brasilia, Pos-Graduacao em Ciencias Genomicas e Biotecnologia, SGAN Quadra 916, Av. W5 Norte, 70790-160 Brasilia, DF (Brazil) [Universidade Catolica de Brasilia, Pos-Graduacao em Ciencias Genomicas e Biotecnologia, SGAN Quadra 916, Av. W5 Norte, 70790-160 Brasilia, DF (Brazil); Bone Biology and Implant Therapy Laboratory, Department of Prosthodontics, University of North Carolina at Chapel Hill, 330 Brauer Hall, CB 7450, Chapel Hill, NC 27599 (United States); Aragao, Francisco J.L. [Universidade Catolica de Brasilia, Pos-Graduacao em Ciencias Genomicas e Biotecnologia, SGAN Quadra 916, Av. W5 Norte, 70790-160 Brasilia, DF (Brazil) [Universidade Catolica de Brasilia, Pos-Graduacao em Ciencias Genomicas e Biotecnologia, SGAN Quadra 916, Av. W5 Norte, 70790-160 Brasilia, DF (Brazil); Embrapa Recursos Geneticos e Biotecnologia, Laboratorio de Introducao e Expressao de Genes, PqEB W5 Norte, 70770-900 Brasilia, DF (Brazil); Cooper, Lyndon F., E-mail: lyndon_cooper@dentistry.unc.edu [Bone Biology and Implant Therapy Laboratory, Department of Prosthodontics, University of North Carolina at Chapel Hill, 330 Brauer Hall, CB 7450, Chapel Hill, NC 27599 (United States)

    2011-01-28T23:59:59.000Z

    Research highlights: {yields} p65 completely blocked HIF-1{alpha} activity at the HRE on different cell lines. {yields} p65 caused minor changes in HIF-1{alpha} and HIF-1{alpha} target genes mRNA expression. {yields} p65 reduced transcription of VEGF promoter. {yields} p65 competes with HIF-1{alpha} for p300. -- Abstract: Hypoxia has emerged as a key determinant of osteogenesis. HIF-1{alpha} is the transcription factor mediating hypoxia responses that include induction of VEGF and related bone induction. Inflammatory signals antagonize bone repair via the NF-{kappa}B pathway. The present investigation explored the functional relationship of hypoxia (HIF-1{alpha} function) and inflammatory signaling (NF-{kappa}B) in stem like and osteoprogenitor cell lines. The potential interaction between HIF-1{alpha} and NF-{kappa}B signaling was explored by co-transfection studies in hFOB with p65, HIF-1{alpha} and 9x-HRE-luc or HIF-1{alpha} target genes reporter plasmids. Nuclear cross-talk was directly tested using the mammalian Gal4/VP16 two-hybrid, and confirmed by co-immunoprecipitation/western blotting assays. The results show that inflammatory stimulation (TNF-{alpha} treatment) causes a marked inhibition of HIF-1{alpha} function at the HRE in all cell lines studied. Also, co-transfection with p65 expression vector leads to reduced hVEGFp transcription after DFO-induced hypoxia. However, TNF-{alpha} treatment had little effect on HIF-1{alpha} mRNA levels. The functional interaction of Gal4-HIF-1{alpha} and VP16-p300 fusion proteins is effectively blocked by expression of p65 in a dose dependent manner. It was concluded that NF-{kappa}B-mediated inflammatory signaling is able to block HIF-1{alpha} transactivation at HRE-encoding genes by direct competition for p300 binding at the promoter. Inflammation may influence the stem cell niche and tissue regeneration by influencing cellular responses to hypoxia.

  19. IDS-NF Impact of Neutrino Cross Section Impact of Neutrino Cross Section

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville PowerCherries 82981-1cnHigh School footballHydrogen andHypernuclei in Hall CInbydoeCELLIDRMSIDS-NF

  20. Applied Math & Statistics: Statistics Minor Curriculum Chart: 2013-2014

    E-Print Network [OSTI]

    Stuart, Josh

    Applied Math & Statistics: Statistics Minor Curriculum Chart: 2013-2014 http PSYC 181 CMPE 108 SOCY 103A CMPS 142 TIM 230 Information on the Statistics Minor The statistics minor as preparation for a graduate degree in statistics or biostatistics. Course Information With permission from

  1. Statistics: Part 1 1. Why bother with statistics?

    E-Print Network [OSTI]

    Francis, Paul

    Statistics: Part 1 1. Why bother with statistics? Why is statistics so necessary for observational. But your data just don't seem to back up their claim. Statistics allows you to determine how confidently) practical introduction to those bits of statistics most vital to observational astronomy. 2. What

  2. FY13 Summary Report on the Augmentation of the Spent Fuel Composition Dataset for Nuclear Forensics: SFCOMPO/NF

    SciTech Connect (OSTI)

    Brady Raap, Michaele C.; Lyons, Jennifer A.; Collins, Brian A.; Livingston, James V.

    2014-03-31T23:59:59.000Z

    This report documents the FY13 efforts to enhance a dataset of spent nuclear fuel isotopic composition data for use in developing intrinsic signatures for nuclear forensics. A review and collection of data from the open literature was performed in FY10. In FY11, the Spent Fuel COMPOsition (SFCOMPO) excel-based dataset for nuclear forensics (NF), SFCOMPO/NF was established and measured data for graphite production reactors, Boiling Water Reactors (BWRs) and Pressurized Water Reactors (PWRs) were added to the dataset and expanded to include a consistent set of data simulated by calculations. A test was performed to determine whether the SFCOMPO/NF dataset will be useful for the analysis and identification of reactor types from isotopic ratios observed in interdicted samples.

  3. FISHERY STATISTICS E UNITED STATES

    E-Print Network [OSTI]

    SH 11 .A443X FISH FISHERY STATISTICS E UNITED STATES ^ 1951 &ch 3. \\§^ ^/'· m:^ STATISTICAL DIGEST. Farley, Director Statistical Digest 30 FISHERY STATISTICS OF THE UNITED STATES 1951 BY A. W. ANDERSON;Fishery Statistics of the United States and Alaska are compiled and published annually to make available

  4. Stellar Evolution A Statistical Model

    E-Print Network [OSTI]

    van Dyk, David

    Stellar Evolution A Statistical Model Statistical Computation Analysis of the Hyades Cluster Embedding Computer Models for Stellar Evolution into a Coherent Statistical Analysis David A. van Dyk1 Analysis of Stellar Evolution #12;Stellar Evolution A Statistical Model Statistical Computation Analysis

  5. ABD56 causes osteoclast apoptosis by inhibiting the NF{kappa}B and ERK pathways

    SciTech Connect (OSTI)

    Idris, Aymen [Rheumatic Diseases Unit, Molecular Medicine Centre, University of Edinburgh, General Western Hospital, Edinburgh, EH4 2XU (United Kingdom); Mrak, Emanuela [Bone Metabolic Unit, Scientific Institute H San Raffaele, via Olgettina 60, 20132 Milano (Italy); Department of Pharmacology, Chemotherapy and Medical Toxicology, University of Milano, via Vanvitelli 32, 20129 Milano (Italy); Greig, Iain [Department of Medicine and Therapeutics, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD (United Kingdom); Guidobono, Francesca [Department of Pharmacology, Chemotherapy and Medical Toxicology, University of Milano, via Vanvitelli 32, 20129 Milano (Italy); Ralston, Stuart H. [Rheumatic Diseases Unit, Molecular Medicine Centre, University of Edinburgh, General Western Hospital, Edinburgh, EH4 2XU (United Kingdom); Hof, Rob van 't [Rheumatic Diseases Unit, Molecular Medicine Centre, University of Edinburgh, General Western Hospital, Edinburgh, EH4 2XU (United Kingdom)], E-mail: rvanthof@staffmail.ed.ac.uk

    2008-06-20T23:59:59.000Z

    We have previously shown that the biphenylcarboxylic acid butanediol ester (ABD56) inhibits osteoclast formation and activity in vitro and in vivo. However, the mechanism of action of this compound is unknown. ABD56 inhibited osteoclast formation and caused osteoclast apoptosis, but had no effects on osteoblasts or macrophages. As the NF{kappa}B and MAPK pathways are essential for osteoclast formation and survival, we studied the effects of ABD56 on these pathways. ABD56 caused phosphorylation of p38, JNK and nuclear translocation of c-jun in osteoclasts. ABD56-induced apoptosis was prevented by the caspase inhibitor zVAD-fmk but was not prevented by the p38- or JNK-inhibitors. ABD56 completely abolished RANKL-induced I{kappa}B and ERK1/2 phosphorylation. Increasing the amount of RANKL partially rescued ABD56-induced apoptosis, indicating that the apoptosis is most probably due to the inhibition of survival signals such as ERK and NF{kappa}B, rather than activation of the p38 or Jnk MAPK pathways.

  6. The influence of coyotes on an urban Canada goose population in the Chicago metropolitan area

    SciTech Connect (OSTI)

    Brown, Justin L.; /Ohio State U.

    2007-01-01T23:59:59.000Z

    Canada geese (Branta canadensis) have become common in many urban areas, often creating nuisance problems for human residents. The presence of urban geese has raised concerns about the spread of disease, increased erosion, excessive noise, eutrophication of waterways, and general nuisance problems. Goose populations have grown due to an increase in urbanization resulting in an abundance of high quality food (urban grass) and suitable nesting sites, as well as a decrease in some predators. I monitored nest predation in the Chicago suburbs during the 2004 and 2005 nesting seasons using 3 nest monitoring techniques to identify predators: video cameras, plasticine eggs, and sign from nest using a classification tree analysis. Of 58 nests monitored in 2004 and 286 in 2005, only raccoons (Procyon lotor) and coyotes (Canis latrans) were identified as nest predators. Raccoons were responsible for 22-25% of depredated nests, but were rarely capable of depredating nests that were actively defended by a goose. Coyotes were responsible for 75-78% of all Canada goose nest depredation and were documented killing one adult goose and feeding on several others. The coyote is a top-level predator that had increased in many metropolitan areas in recent years. To determine if coyotes were actively hunting geese or eggs during the nesting season, I analyzed coyote habitat selection between nesting and pre-nesting or post-nesting seasons. Coyote home ranges (95% Minimum Convex Polygon) were calculated for 19 coyotes to examine third order habitat selection related to goose nest abundance. A 100 m buffer (buffer habitat) was created and centered on each waterway edge and contained 90% of all nests. Coyotes showed selection for habitats during all seasons. Buffer habitat was the top ranked habitat in both pre-nesting and nesting seasons, but dropped to third ranked in post-nesting season. Habitat selection across seasons was compared using a repeated measures MANOVA. Habitat selection between pre-nesting and nesting seasons (P=0.72) were similar, while between post-nesting and nesting seasons there was a nearly significant difference (P=0.07). The insignificant change in habitat use across seasons suggests that coyotes did not switch habitat use to take advantage of goose nests. Alternatively, the change in ranking of buffer habitat across seasons suggests that coyotes may have switched habitat use to take advantage of goose nests. The results are not clear as large individual variation between coyotes due to differences in habitat availability, and social status interfere with the results of the analysis. Even though I failed to find strong support for coyotes actively hunting goose nests, they nevertheless were the primary nest predator in the area and may influence Canada goose populations. To determine the potential influence of coyotes on the Canada goose population, I created a Canada goose matrix population model that included variables such as coyote predation on adults and nests as well as coyote influence on nest desertion. Using the base population model I calculated the Canada goose population to be increasing with {lambda} = 1.055. The removal of all coyote influence on the goose population would allow {lambda} to increase to 1.214. Nest predation was the most important factor related to coyotes: the removal of coyote nest predation from the model resulted in a population growth rate {lambda} = 1.157. Modeling results suggest coyotes are serving as a limiting factor for the Canada goose population within the Chicago metropolitan area.

  7. A comprehensive study of Superfund program benefits in the Denver and Tampa Bay metropolitan areas

    SciTech Connect (OSTI)

    Held, K.; Casper, B.; Siddhanti, S.K. [Booz Allen and Hamilton, Inc., McLean, VA (United States); Smith, E.R. [Environmental Protection Agency, Washington, DC (United States)

    1995-12-31T23:59:59.000Z

    The purpose of the study is to evaluate the benefits of the Superfund program in selected geographic areas. The study demonstrates how the cleanup of Superfund sites has improved the overall quality of life of those in the affected communities. The study presents findings on the benefits of Superfund cleanup activity in the Denver, Colorado and Tampa Bay, Florida metropolitan areas. Denver and Tampa Bay were chosen from several areas that the EPA evaluated and screened during the initial phase of the study. These locations were chosen because of a substantial presence of Superfund activities, making it possible to assess the efficacy of the program. Several features make this study unique in terms of its overall goal. The study examines a broad range of benefit categories related to human health, environmental, and socioeconomic effects of Superfund cleanup activities. The study is also designed to assess benefits due to completed, current, and future planned activity at Superfund sites. This assessment covers Federal remedial activities at National Priorities List (NPL) sites, as well as relevant Federal removal actions in the study areas. These benefits are investigated from an area-wide perspective, as opposed to site-by-site, to determine Superfund`s overall effect on the communities in each area. The study consists of two major phases: Phase 1: Screening and ranking 16 prospective geographic areas and selecting Denver and Tampa Bay as the most appropriate areas for in-depth analysis; and Phase 2: Developing methodologies for assessing benefits, collecting relevant data, and analyzing the benefits from Superfund cleanup activity.

  8. School of Mathematics and Statistics

    E-Print Network [OSTI]

    Du, Jie

    School of Mathematics and Statistics Faculties of Arts Economics, Education, Engineering and Science INTERMEDIATE MATHEMATICS and STATISTICS 2012 THE UNIVERSITY OF SYDNEY #12;Contents 1. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 STAT2911 Probability and Statistical Models (Advanced) . . . . . . . . . . . 16 STAT2912

  9. Lipid metabolism enzyme 5-LOX and its metabolite LTB4 are capable of activating transcription factor NF-{kappa}B in hepatoma cells

    SciTech Connect (OSTI)

    Zhao, Yu [Department of Biochemistry, College of Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071 (China)] [Department of Biochemistry, College of Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071 (China); Wang, Wenhui [Department of Interventional Radiography, First Hospital of Lanzhou University, No.1 Donggang West Road, Lanzhou, Gansu Province 730000 (China)] [Department of Interventional Radiography, First Hospital of Lanzhou University, No.1 Donggang West Road, Lanzhou, Gansu Province 730000 (China); Wang, Qi [Department of Cancer Research, Institute for Molecular Biology, College of Life Sciences, Nankai University, Tianjin 300071 (China)] [Department of Cancer Research, Institute for Molecular Biology, College of Life Sciences, Nankai University, Tianjin 300071 (China); Zhang, Xiaodong, E-mail: zhangxd@nankai.edu.cn [Department of Cancer Research, Institute for Molecular Biology, College of Life Sciences, Nankai University, Tianjin 300071 (China)] [Department of Cancer Research, Institute for Molecular Biology, College of Life Sciences, Nankai University, Tianjin 300071 (China); Ye, Lihong, E-mail: yelihong@nankai.edu.cn [Department of Biochemistry, College of Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071 (China)] [Department of Biochemistry, College of Life Sciences, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071 (China)

    2012-02-24T23:59:59.000Z

    Highlights: Black-Right-Pointing-Pointer 5-LOX is able to upregulate expression of NF-{kappa}B p65. Black-Right-Pointing-Pointer 5-LOX enhances nuclear translocation of NF-{kappa}B p65 via increasing p-I{kappa}B-{alpha} level. Black-Right-Pointing-Pointer 5-LOX stimulates transcriptional activity of NF-{kappa}B in hepatoma cells. Black-Right-Pointing-Pointer LTB4 activates transcriptional activity of NF-{kappa}B in hepatoma cells. -- Abstract: The issue that lipid metabolism enzyme and its metabolites regulate transcription factors in cancer cell is not fully understood. In this study, we first report that the lipid metabolism enzyme 5-Lipoxygenase (5-LOX) and its metabolite leukotriene B4 (LTB4) are capable of activating nuclear factor-{kappa}B (NF-{kappa}B) in hepatoma cells. We found that the treatment of MK886 (an inhibitor of 5-LOX) or knockdown of 5-LOX was able to downregulate the expression of NF-{kappa}B p65 at the mRNA level and decreased the phosphorylation level of inhibitor {kappa}B{alpha} (I{kappa}B{alpha}) in the cytoplasm of hepatoma HepG2 or H7402 cells, which resulted in the decrease of the level of nuclear NF-{kappa}B p65. These were confirmed by immunofluorescence staining in HepG2 cell. Moreover, the above treatments were able to decrease the transcriptional activity of NF-{kappa}B in the cells. The LTB4, one of metabolites of 5-LOX, is responsible for 5-LOX-activated NF-{kappa}B in a dose-dependent manner. Thus, we conclude that the lipid metabolism enzyme 5-LOX and its metabolite LTB4 are capable of activating transcription factor NF-{kappa}B in hepatoma cells. Our finding provides new insight into the significance of lipid metabolism in activation of transcription factors in cancer.

  10. Statistics applied to safeguards

    SciTech Connect (OSTI)

    Picard, R.R.

    1993-05-01T23:59:59.000Z

    Statistical methods are central to safeguards work. Measurements forming the basis of much materials accountancy are not perfect - ``perfect`` in the sense of being error free. Other sessions in this course address the destructive and nondestructive measurement of nuclear material, together with the inherent limitations in those measurements. The bottom line is that measurement errors are a fact of life and, since we can`t eliminate them, we have to find a rational way to deal with them. Which leads to the world of statistics. Beyond dealing with measurement errors, another area of statistical application involves the sampling of items for verification. Inspectors from the IAEA and domestic regulatory agencies periodically visit operating facilities and make measurements of selected items. By comparing their own measured values to those declared by the facilities, increased confidence is obtained. If verification measurements were not expensive, time consuming, and disruptive to operations, perhaps verification of 100% of the inventories would be desirable. In reality, many constraints lead to inspection of only a portion of those inventories. Drawing inferences about a larger ``population`` of declared items in a facility based on verification information obtained from a sample of those items is a statistical problem. There are few texts on statistics in safeguards. The lengthy exposition ``IAEA Safeguards: Statistical Concepts and Techniques`` and the US NRC book edited by Bowen and Bennet are two good sources of general information. In the next section, the subject of measurement quality is addressed. The third section covers the evaluation of MUFs, and discusses the related subjects of error propagation and sequential analysis. The final section covers verification, inspection sample size calculations, and the D statistic. The text is written at an elementary level, with references to the safeguards literature for more detailed treatment.

  11. Statistics applied to safeguards

    SciTech Connect (OSTI)

    Picard, R.R.

    1993-01-01T23:59:59.000Z

    Statistical methods are central to safeguards work. Measurements forming the basis of much materials accountancy are not perfect - perfect'' in the sense of being error free. Other sessions in this course address the destructive and nondestructive measurement of nuclear material, together with the inherent limitations in those measurements. The bottom line is that measurement errors are a fact of life and, since we can't eliminate them, we have to find a rational way to deal with them. Which leads to the world of statistics. Beyond dealing with measurement errors, another area of statistical application involves the sampling of items for verification. Inspectors from the IAEA and domestic regulatory agencies periodically visit operating facilities and make measurements of selected items. By comparing their own measured values to those declared by the facilities, increased confidence is obtained. If verification measurements were not expensive, time consuming, and disruptive to operations, perhaps verification of 100% of the inventories would be desirable. In reality, many constraints lead to inspection of only a portion of those inventories. Drawing inferences about a larger population'' of declared items in a facility based on verification information obtained from a sample of those items is a statistical problem. There are few texts on statistics in safeguards. The lengthy exposition IAEA Safeguards: Statistical Concepts and Techniques'' and the US NRC book edited by Bowen and Bennet are two good sources of general information. In the next section, the subject of measurement quality is addressed. The third section covers the evaluation of MUFs, and discusses the related subjects of error propagation and sequential analysis. The final section covers verification, inspection sample size calculations, and the D statistic. The text is written at an elementary level, with references to the safeguards literature for more detailed treatment.

  12. mm-Wave Op-Amps employing simple-Miller compensation, with OIP3/PDC ratios of 211 (10 dB NF) and 144 (6.0 dB NF) at 2 GHz

    E-Print Network [OSTI]

    Rodwell, Mark J. W.

    mm-Wave Op-Amps employing simple-Miller compensation, with OIP3/PDC ratios of 211 (10 dB NF/PDC ratio at fs = 2-3 GHz, compared to state-of-the-art. We address considerations important 1000 mW power dissipation PDC . This very high ratio of output-referred third-order-intercept power

  13. Modeling green fluorescent protein transcription, translation and modification as a method to obtain NF-kappaB activation profiles

    E-Print Network [OSTI]

    Laible, Allyson Marie

    2009-05-15T23:59:59.000Z

    that fluorescence increases up to 24 hours after an initial delay of approximately four hours. The fluorescence data was also used to develop a model describing significant events leading to NF-?B activation and GFP expression. In addition, a model describing...

  14. TCR and CD28 activate the transcription factor NF- B in T-cells viadistinct adaptor signaling complexes

    E-Print Network [OSTI]

    Thaker, Youg Raj; Schneider, Helga; Rudd, Christopher E.

    2014-10-23T23:59:59.000Z

    of NF-{kappa}B activation in T cells via association of the adapter proteins ADAP and CARMA1. Science 2007;316:754–8. [30] Sommer K, Guo B, Pomerantz JL, Bandaranayake AD, Moreno-García ME, Ovechkina YL, et al. Phosphorylation of the CARMA1 linker...

  15. Enhancement of CD8+ T-cell memory by removal of a vaccinia virus NF-?B inhibitor

    E-Print Network [OSTI]

    Ren, Hongwei; Ferguson, Brian J.; de Motes, Carlos Maluquer; Sumner, Rebecca P.; Harman, Laura; Smith, Geoffrey L.

    2014-11-07T23:59:59.000Z

    induction of NF-kappaB activation via an ERK2 pathway in virus-infected human embryonic kidney cells. J Virol 2006;80(17):8676-85. 63. Harte MT, Haga IR, Maloney G, et al. The poxvirus protein A52R targets Toll-like receptor signaling complexes...

  16. Mast cell chymase induces smooth muscle cell apoptosis by disrupting NF-{kappa}B-mediated survival signaling

    SciTech Connect (OSTI)

    Leskinen, Markus J. [Wihuri Research Institute, Kalliolinnantie 4, FI-00140 Helsinki (Finland); Heikkilae, Hanna M. [Wihuri Research Institute, Kalliolinnantie 4, FI-00140 Helsinki (Finland); Speer, Mei Y. [Bioengineering Department, University of Washington, Seattle, WA 98195 (United States); Hakala, Jukka K. [Wihuri Research Institute, Kalliolinnantie 4, FI-00140 Helsinki (Finland); Laine, Mika [Department of Medicine, Helsinki University Central Hospital and Minerva Institute for Medical Research, Helsinki (Finland); Kovanen, Petri T. [Wihuri Research Institute, Kalliolinnantie 4, FI-00140 Helsinki (Finland); Lindstedt, Ken A. [Wihuri Research Institute, Kalliolinnantie 4, FI-00140 Helsinki (Finland)]. E-mail: ken.lindstedt@wri.fi

    2006-05-01T23:59:59.000Z

    Chymase released from activated mast cells induces apoptosis of vascular smooth muscle cells (SMCs) in vitro by degrading the pericellular matrix component fibronectin, so causing disruption of focal adhesion complexes and Akt dephosphorylation, which are necessary for cell adhesion and survival. However, the molecular mechanisms of chymase-mediated apoptosis downstream of Akt have remained elusive. Here, we show by means of RT-PCR, Western blotting, EMSA, immunocytochemistry and confocal microscopy, that chymase induces SMC apoptosis by disrupting NF-{kappa}B-mediated survival signaling. Following chymase treatment, the translocation of active NF-{kappa}B/p65 to the nucleus was partly abolished and the amount of nuclear p65 was reduced. Pretreatment of SMCs with chymase also inhibited LPS- and IL-1{beta}-induced nuclear translocation of p65. The chymase-induced degradation of p65 was mediated by active caspases. Loss of NF-{kappa}B-mediated transactivation resulted in downregulation of bcl-2 mRNA and protein expression, leading to mitochondrial swelling and release of cytochrome c. The apoptotic process involved activation of both caspase 9 and caspase 8. The results reveal that, by disrupting the NF-{kappa}B-mediated survival-signaling pathway, activated chymase-secreting mast cells can mediate apoptosis of cultured arterial SMCs. Since activated mast cells colocalize with apoptotic SMCs in vulnerable areas of human atherosclerotic plaques, they may participate in the weakening and rupture of atherosclerotic plaques.

  17. Journal of Membrane Science 256 (2005) 134142 Characterization of novel acid-stable NF membranes before and after

    E-Print Network [OSTI]

    Freger, Viatcheslav "Slava"

    2005-01-01T23:59:59.000Z

    to hot 20% sulfuric acid solutions for various times. Swelling and morphological changes measured Nanofiltration (NF) membranes represent a class of mem- branes with capabilities to selectively separate low- sulfone, which support an ultra-thin selective layer a few tens to a few hundred of nanometers thick

  18. Statistics and samples 1.1 What is statistics?

    E-Print Network [OSTI]

    Irwin, Darren

    1 1 Statistics and samples 1.1 What is statistics? Biologists study the properties of living things to get sam- pled and who did not. Statistics is a technology that describes and measures aspects of nature from samples. Most importantly, statistics lets us quantify the uncertainty of these meas- ures

  19. Pearson's Goodness of Fit Statistic as a Score Test Statistic

    E-Print Network [OSTI]

    Smyth, Gordon K.

    Pearson's Goodness of Fit Statistic as a Score Test Statistic Gordon K. Smyth Abstract For any generalized linear model, the Pearson goodness of fit statistic is the score test statistic for testing and the residual deviance is therefore the relationship between the score test and the likelihood ratio test

  20. Statistical Learning Theory of Protein Dynamics

    E-Print Network [OSTI]

    Haas, Kevin

    2013-01-01T23:59:59.000Z

    integrated statistical learning and simulation approach tomolecular simulation, using statistical learning theory tomolecular simulation and statistical learning theory of

  1. D-Dbar Mixing in the Standard Model and Beyond from Nf=2 Twisted Mass QCD

    E-Print Network [OSTI]

    N. Carrasco; M. Ciuchini; P. Dimopoulos; R. Frezzotti; V. Gimenez; V. Lubicz; G. C. Rossi; F. Sanfilippo; L. Silvestrini; S. Simula; C. Tarantino

    2014-06-13T23:59:59.000Z

    We present the first unquenched lattice QCD results for the bag parameters controlling the short distance contribution to D meson oscillations in the Standard Model and beyond. We have used the gauge configurations produced by the European Twisted Mass Collaboration with Nf = 2 dynamical quarks, at four lattice spacings and light meson masses in the range 280-500 MeV. Renormalization is carried out non-perturbatively with the RI-MOM method. The bag-parameter results have been used to constrain New Physics effects in D-Dbar mixing, to put a lower bound to the generic New Physics scale and to constrain off-diagonal squark mass terms for TeV-scale Supersymmetry.

  2. Ascorbic acid suppresses endotoxemia and NF-?B signaling cascade in alcoholic liver fibrosis in guinea pigs: A mechanistic approach

    SciTech Connect (OSTI)

    Abhilash, P.A.; Harikrishnan, R.; Indira, M., E-mail: indiramadambath@gmail.com

    2014-01-15T23:59:59.000Z

    Alcohol consumption increases the small intestinal bacterial overgrowth (SIBO) and intestinal permeability of endotoxin. The endotoxin mediated inflammatory signaling plays a major role in alcoholic liver fibrosis. We evaluated the effect of ascorbic acid (AA), silymarin and alcohol abstention on the alcohol induced endotoxemia and NF-?B activation cascade pathway in guinea pigs (Cavia porcellus). Guinea pigs were administered ethanol at a daily dose of 4 g/kg b.wt for 90 days. After 90 days, ethanol administration was stopped. The ethanol treated animals were divided into abstention, silymarin (250 mg/kg b.wt) and AA (250 mg/kg b.wt) supplemented groups and maintained for 30 days. The SIBO, intestinal permeability and endotoxin were significantly increased in the ethanol group. The mRNA expressions of intestinal proteins claudin, occludin and zona occludens-1 were significantly decreased in ethanol group. The mRNA levels of inflammatory receptors, activity of IKK? and the protein expressions of phospho-I?B?, NF-?B, TNF-?, TGF-?{sub 1} and IL-6 were also altered in ethanol group. The expressions of fibrosis markers ?-SMA, ?{sub 1} (I) collagen and sirius red staining in the liver revealed the induction of fibrosis. But the supplementation of AA could induce greater reduction of ethanol induced SIBO, intestinal barrier defects, NF-?B activation and liver fibrosis than silymarin. The possible mechanism may be the inhibitory effect of AA on SIBO, intestinal barrier defect and IKK?, which decreased the activation of NF-?B and synthesis of cytokines. This might have led to suppression of HSCs activation and liver fibrosis. - Highlights: • Alcohol increases intestinal bacterial overgrowth and permeability of endotoxin. • Endotoxin mediated inflammation plays a major role in alcoholic liver fibrosis. • Ascorbic acid reduces endotoxemia, NF-?B activation and proinflammatory cytokines. • AA's action is by inhibition of SIBO, IKK? and alteration of intestinal permeability. • This might have led to suppression of HSCs activation and liver fibrosis.

  3. Experimental Mathematics and Computational Statistics

    SciTech Connect (OSTI)

    Bailey, David H.; Borwein, Jonathan M.

    2009-04-30T23:59:59.000Z

    The field of statistics has long been noted for techniques to detect patterns and regularities in numerical data. In this article we explore connections between statistics and the emerging field of 'experimental mathematics'. These includes both applications of experimental mathematics in statistics, as well as statistical methods applied to computational mathematics.

  4. STATISTICS ESSENTIAL SKILL OUTCOME STATEMENTS

    E-Print Network [OSTI]

    Gering, Jon C.

    to statistical literacy. The American Statistical Association endorsed the Guidelines for AssessmentSB #3205 STATISTICS ESSENTIAL SKILL OUTCOME STATEMENTS Newly-Revised Version: A liberally educated person is capable of being both a producer and a consumer of statistical information with some basic

  5. Chemical evolution of volatile organic compounds in the outflow of the Mexico City Metropolitan area

    SciTech Connect (OSTI)

    Apel, Eric; Emmons, L.; Karl, Thomas G.; Flocke, Frank M.; Hills, A. J.; Madronich, Sasha; Lee-Taylor, J.; Fried, Alan; Weibring, P.; Walega, J.; Richter, Dirk; Tie, X.; Mauldin, L.; Campos, Teresa; Weinheimer, Andrew J.; Knapp, David; Sive, B.; Kleinman, Lawrence I.; Springston, S.; Zaveri, Rahul A.; Ortega, John V.; Voss, Paul B.; Blake, D. R.; Baker, Angela K.; Warneke, Carsten; Welsh-Bon, Daniel; de Gouw, Joost A.; Zheng, J.; Zhang, Renyi; Rudolph, Jochen; Junkermann, W.; Riemer, D.

    2010-01-01T23:59:59.000Z

    The volatile organic compound (VOC) distribution in the Mexico City Metropolitan Area (MCMA) and its evolution as it is uplifted and transported out of the MCMA basin was studied during the 2006 MILAGRO/MIRAGE-Mex field campaign. The results show that in the morning hours in the city center, the VOC distribution is dominated by non-methane hydrocarbons (NMHCs) but with a substantial contribution from oxygenated volatile organic compounds (OVOCs), predominantly from primary emissions. Alkanes account for a large part of the NMHC distribution in terms of mixing ratios. In terms of reactivity, NMHCs also dominate overall, especially in the morning hours. However, in the afternoon, as the boundary layer lifts and air is mixed and aged within the basin, the distribution changes as secondary products are formed. The WRF-Chem (Weather Research and Forecasting with Chemistry) model and MOZART (Model for Ozone and Related chemical Tracers) were able to reproduce the general features of the daytime cycle of the VOC OH reactivity distribution showing that NMHCs dominate the distribution except in the afternoon hours and that the VOC OH reactivity peaks in the early morning due to high morning emissions from the city into a shallow boundary layer. The WRF-Chem and MOZART models showed higher reactivity than the experimental data during the nighttime cycle, perhaps indicating problems with the modeled nighttime boundary layer height. In addition, a plume was studied in which air was advected out of the MCMA and intercepted downwind with the DOE G1 on March 18 and the NCAR C130 one day later on March 19. A number of identical species measured aboard each aircraft gave insight into the chemical evolution of the plume as it aged and was transported as far as 1000 km downwind. Ozone and many OVOCs were photochemically produced in the plume. The WRF-Chem and MOZART models were used to examine the spatial and temporal extent of the March 19 plume and to help interpret the OH reactivity in the downwind plume. The model results generally showed good agreement with experimental results for the total VOC OH reactivity downwind and gave insight into the distributions of VOC chemical classes downwind. A box model with detailed gas phase chemistry (NCAR Master Mechanism), initialized with concentrations observed at one of the ground sites in the MCMA, was used to examine the expected evolution of specific VOCs over a 1-2 day period. The models clearly supported the experimental evidence for NMHC oxidation leading to the formation of OVOCs downwind, which then become the primary fuel for ozone production far away from the MCMA.

  6. General Indicators: Performance Statistics

    E-Print Network [OSTI]

    Webb, Peter

    Bank Central Svcs. Energy Mgmt Admin Preventive Maintenance: Fire/Life/Safety (FLS) 87% -4% 100% 47 Trend Initial Target Steam Chilled Utility Outages 2 +1% 0 0 0 Preventive Maintenance: Fire participation reading will be June 2012 *Budget data FYTD through March 2012 Maintenance: Performance Statistics

  7. General Indicators: Performance Statistics

    E-Print Network [OSTI]

    Webb, Peter

    Bank Central Svcs. Energy Mgmt Admin Preventive Maintenance: Fire/Life/Safety (FLS) 85% -12% 100% 80 Trend Initial Target Steam Chilled Utility Outages 3 -5 0 1 0 Preventive Maintenance: Fire participation reading will be August 2012 *Budget data FYTD through May 2012 Maintenance: Performance Statistics

  8. General Indicators: Performance Statistics

    E-Print Network [OSTI]

    Webb, Peter

    . Energy Mgmt Admin Preventive Maintenance: Fire/Life/Safety (FLS) 97% +10% 100% 96% 93% 99% 98% Non Chilled Utility Outages 8 +6% 0 1 2 Preventive Maintenance: Fire/Life/Safety (FLS) 100% No Change 100 will be June 2012 *Budget data FYTD through April 2012 Maintenance: Performance Statistics Current Month Change

  9. BS in STATISTICS: Statistical Science Emphasis (695220) MAP Sheet Department of Statistics

    E-Print Network [OSTI]

    Seamons, Kent E.

    the statistics list: C S 142 Introduction to Computer Programming Math 334 Ordinary Differential Equations Math Academic Internship: Statistics Stat 497R Introduction to Statistical Research Stat 535 Applied Linear are strongly recommended to choose electives to prepare for the BYU BS/MS statistics integrated program

  10. NF-kB activity-dependent P-selectin involved in ox-LDL-induced foam cell formation in U937 cell

    SciTech Connect (OSTI)

    Wang, Yi, E-mail: wangyi2004a@126.com [Department of Cardiology, Shanghai First People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200080 (China)] [Department of Cardiology, Shanghai First People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200080 (China); Wang, Xiang; Sun, Minghui; Zhang, Zhenyu; Cao, Heng; Chen, Xiaoqing [Department of Cardiology, Shanghai First People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200080 (China)] [Department of Cardiology, Shanghai First People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200080 (China)

    2011-08-05T23:59:59.000Z

    Highlights: {yields} Ox-LDL induced foam cell formation in the human U937 promonocytic cell line in a dose- and time-dependent manner. {yields} Ox-LDL induced expression of P-selectin through degradation of IkBa and augment of NF-kB activity and protein level during macrophage-derived foam cell formation. {yields} P-selectin and NF-kB may be identified as pivotal regulators of ox-LDL-induced foam cell formation. {yields} Therapy based on the inhibition of P-selectin and NF-kB may complement conventional treatments to prevent atherosclerosis. -- Abstract: Oxidized low-density lipoprotein (ox-LDL) plays a critical role in regulation of atherosclerosis. However, little is known about the role of Nuclear factor kB (NF-kB) activity-dependent P-selectin in ox-LDL-induced foam cell formation during atherosclerosis. In this study, we first investigated ox-LDL induced foam cell formation in the human U937 promonocytic cell line in a dose- and time-dependent manner. Treatment of U937 cells with ox-LDL increased lipid accumulation as well as intracellular cholesterol content. Next, a comparative analysis of gene expression profiling using cDNA microarray and Real-time-PCR indicated that ox-LDL exposure induced, in three treated groups, an extremely marked increase in the mRNA level of P-selectin. Protein levels of P-selectin and its upstream regulators IkBa and NF-kB showed that NF-kB pathway is involved in the ox-LDL-induced foam cell formation. Finally, overexpression of NF-kB significantly accelerated, whereas, inhibition of NF-kB with siRNA remarkably attenuated ox-LDL-induced macrophage-derived foam cell formation. It was concluded that the activity of NF-kB is augmented during macrophage-derived foam cell formation. Activation of NF-kB increased, whereas, inhibition of NF-kB decreased ox-LDL-induced P-selectin expression and lipid accumulation in macrophages, suggesting ox-LDL induced expression of P-selectin through degradation of IkBa and activation of NF-kB in the regulation of foam cell formation.

  11. Sanders, J. E.; and Merguerian, Charles, 1992a, Directional history of Pleistocene glaciers inferred from features eroded on bedrock, New York metropolitan area, SE NY.

    E-Print Network [OSTI]

    Merguerian, Charles

    Sanders, J. E.; and Merguerian, Charles, 1992a, Directional history of Pleistocene glaciers inferred from features eroded on bedrock, New York metropolitan area, SE NY. If a glacier erodes bedrock, the usual perception is that the youngest glacier will obliterate all direction-of-flow evidence that any

  12. 1979 DOE statistical symposium

    SciTech Connect (OSTI)

    Gardiner, D.A.; Truett T. (comps. and eds.)

    1980-09-01T23:59:59.000Z

    The 1979 DOE Statistical Symposium was the fifth in the series of annual symposia designed to bring together statisticians and other interested parties who are actively engaged in helping to solve the nation's energy problems. The program included presentations of technical papers centered around exploration and disposal of nuclear fuel, general energy-related topics, and health-related issues, and workshops on model evaluation, risk analysis, analysis of large data sets, and resource estimation.

  13. Homotopy in statistical physics

    E-Print Network [OSTI]

    Ralph Kenna

    2006-04-12T23:59:59.000Z

    In condensed matter physics and related areas, topological defects play important roles in phase transitions and critical phenomena. Homotopy theory facilitates the classification of such topological defects. After a pedagogic introduction to the mathematical methods involved in topology and homotopy theory, the role of the latter in a number of mainly low-dimensional statistical-mechanical systems is outlined. Some recent activities in this area are reviewed and some possible future directions are discussed.

  14. Bayesian Statistics Stochastic Simulation -Gibbs sampling

    E-Print Network [OSTI]

    Wright, Francis

    Bayesian Statistics Stochastic Simulation - Gibbs sampling Bayesian Statistics - an Introduction Dr Pettit Bayesian Statistics - an Introduction #12;Bayesian Statistics Stochastic Simulation - Gibbs sampling What is Bayesian Statistics? Bayes Theorem The Likelihood Principle Mixtures of conjugate priors

  15. C. Shane Reese Department of Statistics

    E-Print Network [OSTI]

    Reese, Shane

    , American Statistical Association 2012 Melvin W. Carter Professorship 2010 Karl G. Maeser Excellence.) 2010 American Statistical Association Excellence in Statistics in Sports Award 2008 Howard Christensen Department of Statistics Honored Faculty Member 2001 Journal of the American Statistical Association

  16. Thermal Reactions of Uranium Metal, UO2, U3O8, UF4, and UO2F2 with NF3 to Produce UF6

    SciTech Connect (OSTI)

    McNamara, Bruce K.; Scheele, Randall D.; Kozelisky, Anne E.; Edwards, Matthew K.

    2009-11-01T23:59:59.000Z

    he objective of this paper is to demonstrate that NF3 fluorinates uranium metal, UO2, UF4, UO3, U3O8, and UO2F2•2H2O to produce the volatile UF6 at temperatures between 100 and 500?C. Thermogravimetric reaction profiles are described that reflect changes in the uranium oxidation state and discrete chemical speciation. Differences in the onset temperatures for each system indicate that NF3-substrate interactions are important for the temperature at which NF3 reacts: U metal > UO3 > UO2 > UO2F2 > UF4 and in fact may indicate different fluorination mechanisms for these various substrates. These studies demonstrate that NF3 is a potential replacement fluorinating agent in the existing nuclear fuel cycle and in oft-proposed actinide volatility reprocessing.

  17. STAT 639V: Topics in Statistics Statistical Computing

    E-Print Network [OSTI]

    Petris, Giovanni

    methods. Most of the topics will be presented in the context of the R statistical computing language (see below). Computing: The computer language we will be using is R. The latest version of R is installedSTAT 639V: Topics in Statistics Fall 2014 Statistical Computing General Information: Class hours

  18. 1 Managed by UT-Battelle for the U.S. Department of Energy NF/IDS Hg Vessel Layout 30 Jun 09

    E-Print Network [OSTI]

    McDonald, Kirk

    1 Managed by UT-Battelle for the U.S. Department of Energy NF/IDS Hg Vessel Layout 30 Jun 09 Cryostat 2 Front Drain Mercury Vessel Concept Matthew F. Glisson Van Graves #12;2 Managed by UT-Battelle;3 Managed by UT-Battelle for the U.S. Department of Energy NF/IDS Hg Vessel Layout 30 Jun 09 Cross Section

  19. INDIAN STATISTICAL INSTITUTE Annual Report

    E-Print Network [OSTI]

    Bandyopadhyay, Antar

    Division 8 Stat-Math Unit (SMU), Kolkata 8 Stat-Math Unit (SMU), Delhi 11 Stat-Math Unit (SMU), Bangalore Stat-Math Unit (SMU), Chennai 14 16 Applied Statistics Division 17 Applied Statistics Unit (ASU

  20. Statistical Performance Modeling of SRAMs

    E-Print Network [OSTI]

    Zhao, Chang

    2011-02-22T23:59:59.000Z

    to their characteristic of low failure rate, while statistical method of yield sensitivity analysis is meaningful for its high efficiency. This thesis proposes a novel statistical model to conduct yield sensitivity prediction on SRAM cells at the simulation level, which...

  1. STATISTICAL MECHANICS AND FIELD THEORY

    E-Print Network [OSTI]

    Samuel, S.A.

    2010-01-01T23:59:59.000Z

    York. K. Bardakci, Field Theory for Solitons, II, BerkeleyFart I Applications of Field Theory Methods to StatisticalStatistical Mechanics to Field Theory Chapter IV The Grand

  2. Comparison of Daytime and Nighttime Populations Adjacent to Interstate Highways in Metropolitan Areas Using LandScan USA

    SciTech Connect (OSTI)

    Johnson, Paul E [ORNL] [ORNL

    2007-01-01T23:59:59.000Z

    An article of similar title was published in the International Journal of Radioactive Materials Transport in 1999. The study concluded that the daytime and nighttime populations are not substantially different for the metropolitan areas examined. This study revisits the issue, but using the LandScan USA high resolution population distribution data, which includes daytime and night-time population. Segments of Interstate highway beltways, along with the direct route through the city, for Atlanta, St. Louis, and Kansas City are examined with an 800m buffer from either side of the highways. The day/night ratio of population is higher using the LandScan USA data. LandScan USA daytime and night-time data will be incorporated into the TRAGIS routing model in future.

  3. Nmero Nome 1T 2T R1T R2T E AC NF 42200 Armando Dias

    E-Print Network [OSTI]

    Baia, Margarida

    Sheet1 Page 1 Número Nome 1T 2T R1T R2T E AC NF 42200 Armando Dias 53515 Jorge Branco 55774 João 70100 Catarina Ferreira 70146 Mariana Castro 70364 Nuno Gaspar 70524 António Grego 10 2 5 70934 João.2 2 15 78167 Afonso Sarmento 13.8 8.3 7.6 2 12 78175 Carlos Martins 14.3 12.6 11 2 14 78183 Ana

  4. Business Statistics 207 Summer, 2013

    E-Print Network [OSTI]

    Barrash, Warren

    Business Statistics 207 Summer, 2013 Instructor: Phil Fry Office: MBEB 3249 e-mail: pfry) & by Appointment Textbook: Business Statistics: A Decision-Making Approach, 8th ed. by Groebner, Shannon, Fry: This is the first semester of a two semester course in business statistics. The objective of BUSSTAT 207

  5. Sulforaphane protects against cytokine- and streptozotocin-induced {beta}-cell damage by suppressing the NF-{kappa}B pathway

    SciTech Connect (OSTI)

    Song, Mi-Young; Kim, Eun-Kyung [Department of Biochemistry, Medical School and Diabetes Research Center, Chonbuk National University, Jeonju, Jeonbuk, 561-756 (Korea, Republic of); Moon, Woo-Sung [Department of Pathology, Medical School and Diabetes Research Center, Chonbuk National University, Jeonju, Jeonbuk, 561-756 (Korea, Republic of); Park, Jin-Woo [Department of Biochemistry, Medical School and Diabetes Research Center, Chonbuk National University, Jeonju, Jeonbuk, 561-756 (Korea, Republic of); Kim, Hyung-Jin; So, Hong-Seob; Park, Raekil [Vestibulocochlear System Research Center, College of Medicine, Wonkwang University, Iksan, Jeonbuk, 570-749 (Korea, Republic of); Kwon, Kang-Beom [Department of Physiology, School of Oriental Medicine, College of Medicine, Wonkwang University, Iksan, Jeonbuk, 570-749 (Korea, Republic of); Vestibulocochlear System Research Center, College of Medicine, Wonkwang University, Iksan, Jeonbuk, 570-749 (Korea, Republic of)], E-mail: desson@wonkwang.ac.kr; Park, Byung-Hyun [Department of Biochemistry, Medical School and Diabetes Research Center, Chonbuk National University, Jeonju, Jeonbuk, 561-756 (Korea, Republic of)], E-mail: bhpark@chonbuk.ac.kr

    2009-02-15T23:59:59.000Z

    Sulforaphane (SFN) is an indirect antioxidant that protects animal tissues from chemical or biological insults by stimulating the expression of several NF-E2-related factor-2 (Nrf2)-regulated phase 2 enzymes. Treatment of RINm5F insulinoma cells with SFN increases Nrf2 nuclear translocation and expression of phase 2 enzymes. In this study, we investigated whether the activation of Nrf2 by SFN treatment or ectopic overexpression of Nrf2 inhibited cytokine-induced {beta}-cell damage. Treatment of RIN cells with IL-1{beta} and IFN-{gamma} induced {beta}-cell damage through a NF-{kappa}B-dependent signaling pathway. Activation of Nrf2 by treatment with SFN and induction of Nrf2 overexpression by transfection with Nrf2 prevented cytokine toxicity. The mechanism by which Nrf2 activation inhibited NF-{kappa}B-dependent cell death signals appeared to involve the reduction of oxidative stress, as demonstrated by the inhibition of cytokine-induced H{sub 2}O{sub 2} production. The protective effect of SFN was further demonstrated by the restoration of normal insulin secreting responses to glucose in cytokine-treated rat pancreatic islets. Furthermore, pretreatment with SFN blocked the development of type 1 diabetes in streptozotocin-treated mice.

  6. Fertilizer Statistics for Texas.

    E-Print Network [OSTI]

    Fraps, G. S. (George Stronach)

    1927-01-01T23:59:59.000Z

    ) H. B. PARKS, B. S.. Apiculturist in Charge A. H. ALEX, B. S.. Queen Breeder FEED CONTROL SERVICE: F. D. FULLER, M. S.. Chief S. D. PEARCE, Secretary J. 13. ROGERS, Feed Inspector W. H. WOOD. Feed Inspector K. L KIRKLAND B S Feed Inspector W... and for selected counties. Estimated prices of plant food are given. The sales of fer- tilizer in the spring are partly related to the price of cotton in the preceding fall and winter. This is shown by statistical methods. CONTENTS ,. A . . . . ,., l...

  7. Independent Statistics & Analysis

    Annual Energy Outlook 2013 [U.S. Energy Information Administration (EIA)]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742 33 111 1,613 122 40Coal Stocks at1,066,688ElectricityLessApril 2015 Independent Statistics &

  8. FY 2009 Statistical Table

    Office of Environmental Management (EM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742 33 1112011 Strategic Plan| Department of.pdf6-OPAMDepartment6 FY 2007 FY 2008State TablesStatistical

  9. ARM - Historical Visitor Statistics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006Datastreamstwrcam40m DocumentationJanuary 9, 2009 [Events, FeatureListGeneral ChangesFieldVisitor Statistics

  10. PDSF Cluster Statistics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Science (SC)IntegratedSpeeding access toTest andOptimize832 2.860 2.864 2.867039 J -Statistics

  11. BS in STATISTICS: Statistical Science Emphasis (695220) MAP Sheet Department of Statistics

    E-Print Network [OSTI]

    Seamons, Kent E.

    the statistics list: C S 142 Introduction to Computer Programming Math 334 Ordinary Differential Equations Math Applied Time Series and Forecasting Stat 474 Theory of Interest Stat 496R Academic Internship: Statistics Stat 497R Introduction to Statistical Research Stat 535 Applied Linear Models Stat 536 Modern

  12. Etching of UO{sub 2} in NF{sub 3} RF Plasma Glow Discharge

    SciTech Connect (OSTI)

    John M. Veilleux

    1999-08-01T23:59:59.000Z

    A series of room temperature, low pressure (10.8 to 40 Pa), low power (25 to 210 W) RF plasma glow discharge experiments with UO{sub 2} were conducted to demonstrate that plasma treatment is a viable method for decontaminating UO{sub 2} from stainless steel substrates. Experiments were conducted using NF{sub 3} gas to decontaminate depleted uranium dioxide from stainless-steel substrates. Depleted UO{sub 2} samples each containing 129.4 Bq were prepared from 100 microliter solutions of uranyl nitrate hexahydrate solution. The amorphous UO{sub 2} in the samples had a relatively low density of 4.8 gm/cm{sub 3}. Counting of the depleted UO{sub 2} on the substrate following plasma immersion was performed using liquid scintillation counting with alpha/beta discrimination due to the presence of confounding beta emitting daughter products, {sup 234}Th and {sup 234}Pa. The alpha emission peak from each sample was integrated using a gaussian and first order polynomial fit to improve quantification. The uncertainties in the experimental measurement of the etched material were estimated at about {+-} 2%. Results demonstrated that UO{sub 2} can be completely removed from stainless-steel substrates after several minutes processing at under 200 W. At 180 W and 32.7 Pa gas pressure, over 99% of all UO{sub 2} in the samples was removed in just 17 minutes. The initial etch rate in the experiments ranged from 0.2 to 7.4 {micro}m/min. Etching increased with the plasma absorbed power and feed gas pressure in the range of 10.8 to 40 Pa. A different pressure effect on UO{sub 2} etching was also noted below 50 W in which etching increased up to a maximum pressure, {approximately}23 Pa, then decreased with further increases in pressure.

  13. Renormalization of local quark-bilinear operators for Nf=3 flavors of SLiNC fermions

    E-Print Network [OSTI]

    M. Constantinou; R. Horsley; H. Panagopoulos; H. Perlt; P. E. L. Rakow; G. Schierholz; A. Schiller; J. M. Zanotti

    2014-08-26T23:59:59.000Z

    The renormalization factors of local quark-bilinear operators are computed non-perturbatively for $N_f=3$ flavors of SLiNC fermions, with emphasis on the various procedures for the chiral and continuum extrapolations. The simulations are performed at a lattice spacing $a=0.074$ fm, and for five values of the pion mass in the range of 290-465 MeV, allowing a safe and stable chiral extrapolation. Emphasis is given in the subtraction of the well-known pion pole which affects the renormalization factor of the pseudoscalar current. We also compute the inverse propagator and the Green's functions of the local bilinears to one loop in perturbation theory. We investigate lattice artifacts by computing them perturbatively to second order as well as to all orders in the lattice spacing. The renormalization conditions are defined in the RI$'$-MOM scheme, for both the perturbative and non-perturbative results. The renormalization factors, obtained at different values of the renormalization scale, are translated to the ${\\bar{\\rm MS}}$ scheme and are evolved perturbatively to 2 GeV. Any residual dependence on the initial renormalization scale is eliminated by an extrapolation to the continuum limit. We also study the various sources of systematic errors. Particular care is taken in correcting the non-perturbative estimates by subtracting lattice artifacts computed to one loop perturbation theory using the same action. We test two different methods, by subtracting either the ${\\cal O}(g^2\\,a^2)$ contributions, or the complete (all orders in $a$) one-loop lattice artifacts.

  14. Application for SAS Certificate Advanced Statistics

    E-Print Network [OSTI]

    Dahl, David B.

    Application for SAS Certificate Advanced Statistics ___________________________________________________________________________________ Student Signature _________________________________________ Date I am a Statistics Major at Brigham Young of Statistics to access my academic information. Brigham Young University Department of Statistics offers

  15. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series PETER HALL Department of Mathematics and Statistics University of Melbourne, Australia Contemporary Frontiers in Statistics THURSDAY and future directions of frontier problems in statistics For further information and about building access

  16. FROM STATISTICAL SIGNIFICANCE TO EFFECT ESTIMATION

    E-Print Network [OSTI]

    Burgman, Mark

    such as the American Psychological Association, and the absence of appropriate editorial pressure, statistical reformFROM STATISTICAL SIGNIFICANCE TO EFFECT ESTIMATION: STATISTICAL REFORM IN PSYCHOLOGY, MEDICINE ABSTRACT Compelling criticisms of statistical significance testing (or Null Hypothesis Significance Testing

  17. APS Operational Statistics for FY 2005

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    asdopslogo1.gif (2896 bytes) APS FY2005 Operational Statistics Back to Main Statistics Page FY 2005 Year-to-Date Statistics 2005 Statistics Summary HTML or PDF FY 2005...

  18. Statistics as a dynamical attractor

    E-Print Network [OSTI]

    Michail Zak

    2012-08-30T23:59:59.000Z

    It is demonstrated that any statistics can be represented by an attractor of the solution to a corresponding systen of ODE coupled with its Liouville equation. Such a non-Newtonian representation allows one to reduce foundations of statistics to better established foundations of ODE. In addition to that, evolution to the attractor reveals possible micro-mechanisms driving random events to the final distribution of the corresponding statistical law. Special attention is concentrated upon the power law and its dynamical interpretation: it is demonstrated that the underlying dynamics supports a " violent reputation" of the power law statistics.

  19. Small Business Goals and Statistics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    & Statistics The Idaho National Laboratory (INL) is committed to supporting the small business objectives of the U.S. Government and the Department of Energy (DOE) and recognizes...

  20. Computer, Computational, and Statistical Sciences Division

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Computing CCS Division Computer, Computational, and Statistical Sciences Division Computational physics, computer science, applied mathematics, statistics and the integration of...

  1. Requirements for Statistics Concentration The Statistics concentration or major may be tailored in accordance with

    E-Print Network [OSTI]

    Stine, Robert A.

    Requirements for Statistics Concentration 6/9/11 The Statistics concentration or major are required, with at least 3 credit units from Statistics. STAT 621 may contribute in Statistics The following courses offered by the Department of Statistics are eligible

  2. International petroleum statistics report

    SciTech Connect (OSTI)

    NONE

    1997-07-01T23:59:59.000Z

    The International Petroleum Statistics Report is a monthly publication that provides current international data. The report presents data on international oil production, demand, imports, and stocks. The report has four sections. Section 1 contains time series data on world oil production, and on oil demand and stocks in the Organization for Economic Cooperation and Development (OECD). This section contains annual data beginning in 1985, and monthly data for the most recent two years. Section 2 presents an oil supply/demand balance for the world. This balance is presented in quarterly intervals for the most recent two years. Section 3 presents data on oil imports by OECD countries. This section contains annual data for the most recent year, quarterly data for the most recent two quarters, and monthly data for the most recent 12 months. Section 4 presents annual time series data on world oil production and oil stocks, demand, and trade in OECD countries. World oil production and OECD demand data are for the years 1970 through 1996; OECD stocks from 1973 through 1996; and OECD trade from 1986 through 1996.

  3. International petroleum statistics report

    SciTech Connect (OSTI)

    NONE

    1995-11-01T23:59:59.000Z

    The International Petroleum Statistics Report presents data on international oil production, demand, imports, exports, and stocks. The report has four sections. Section 1 contains time series data on world oil production, and on oil demand and stocks in the Organization for Economic Cooperation and Development (OECD). This section contains annual data beginning in 1985, and monthly data for the most recent two years. Section 2 presents an oil supply/demand balance for the world. This balance is presented in quarterly intervals for the most recent two years. Section 3 presents data on oil imports by OECD countries. This section contains annual data for the most recent year, quarterly data for the most recent two quarters, and monthly data for the most recent twelve months. Section 4 presents annual time series data on world oil production and oil stocks, demand, and trade in OECD countries. World oil production and OECD demand data are for the years 1970 through 1994; OECD stocks from 1973 through 1994; and OECD trade from 1984 through 1994.

  4. Models for Millions Department of Statistics

    E-Print Network [OSTI]

    Stine, Robert A.

    Models for Millions Bob Stine Department of Statistics The Wharton School, UniversityDepartment of Statistics Introduction #12;WhartonDepartment of Statistics WhartonDepartment of Statistics Statistics in the News Hot topics Big Data Business Analytics Data Science Are the authors talking about statistics

  5. Determination of c_sw in N_f=3+1 Lattice QCD with massive Wilson fermions

    E-Print Network [OSTI]

    Patrick Fritzsch; Rainer Sommer; Felix Stollenwerk; Ulli Wolff

    2015-01-27T23:59:59.000Z

    We develop a strategy for the non-perturbative determination of the O(a)-improvement coefficient c_sw for Wilson fermions with massive sea quarks. The improvement condition is defined via the PCAC relation in the Schr\\"odinger functional. It is imposed along a line of constant physics designed to be close to the correct mass of the charm quark. The numerical work uses the tree-level improved L\\"uscher-Weisz gauge action in N_f=3+1 Lattice QCD.

  6. A (P)HMC algorithm for N_f = 2 + 1 + 1 flavours of twisted mass fermions

    E-Print Network [OSTI]

    T. Chiarappa; R. Frezzotti; C. Urbach

    2005-09-27T23:59:59.000Z

    We present a detailed design of a (P)HMC simulation algorithm for N_f = 2 + 1 + 1 maximally twisted Wilson quark flavours. The algorithm retains even/odd and mass-shift preconditionings combined with multiple Molecular Dynamics time scales for both the light mass degenerate, u and d, quarks and the heavy mass non-degenerate, s and c, quarks. Various non-standard aspects of the algorithm are discussed, among which those connected to the use of a polynomial approximation for the inverse (square root of the squared) Dirac matrix in the s and c quark sector.

  7. Natural Proteasome Inhibitor Celastrol Suppresses Androgen-Independent Prostate Cancer Progression by Modulating Apoptotic Proteins and NF-kappaB

    E-Print Network [OSTI]

    Dai, Yao; Jeffrey, Tang; Wenhua, Xiaojie; Meng, Yang; Burstein, Ezra; Lawrence, Theodore S.; Xu, Liang

    2010-12-10T23:59:59.000Z

    Apoptotic Proteins and NF-kappaB. PLoS ONE 5(12): e14153. doi:10.1371/journal.pone.0014153 Editor: Gen Sheng Wu, Wayne State University, United States of America Received July 10, 2010; Accepted November 10, 2010; Published December 10, 2010 Copyright: #2... through a University of Michigan Cancer Center Support Grant [5 P30 CA46592]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Competing Interests: The authors have declared...

  8. SDI: Statistical dynamic interactions

    SciTech Connect (OSTI)

    Blann, M.; Mustafa, M.G. (Lawrence Livermore National Lab., CA (USA)); Peilert, G.; Stoecker, H.; Greiner, W. (Frankfurt Univ. (Germany, F.R.). Inst. fuer Theoretische Physik)

    1991-04-01T23:59:59.000Z

    We focus on the combined statistical and dynamical aspects of heavy ion induced reactions. The overall picture is illustrated by considering the reaction {sup 36}Ar + {sup 238}U at a projectile energy of 35 MeV/nucleon. We illustrate the time dependent bound excitation energy due to the fusion/relaxation dynamics as calculated with the Boltzmann master equation. An estimate of the mass, charge and excitation of an equilibrated nucleus surviving the fast (dynamic) fusion-relaxation process is used as input into an evaporation calculation which includes 20 heavy fragment exit channels. The distribution of excitations between residue and clusters is explicitly calculated, as is the further deexcitation of clusters to bound nuclei. These results are compared with the exclusive cluster multiplicity measurements of Kim et al., and are found to give excellent agreement. We consider also an equilibrated residue system at 25% lower initial excitation, which gives an unsatisfactory exclusive multiplicity distribution. This illustrates that exclusive fragment multiplicity may provide a thermometer for system excitation. This analysis of data involves successive binary decay with no compressional effects nor phase transitions. Several examples of primary versus final (stable) cluster decay probabilities for an A = 100 nucleus at excitations of 100 to 800 MeV are presented. From these results a large change in multifragmentation patterns may be understood as a simple phase space consequence, invoking neither phase transitions, nor equation of state information. These results are used to illustrate physical quantities which are ambiguous to deduce from experimental fragment measurements. 14 refs., 4 figs.

  9. Probability, Statistics, and Stochastic Processes

    E-Print Network [OSTI]

    Olofsson, Peter

    , science, and engineering students. Other than the basic probability theory, my goal was to in- cludeProbability, Statistics, and Stochastic Processes Peter Olofsson A Wiley-Interscience Publication had been teaching a course on calculus-based probability and statistics mainly for mathematics

  10. Key China Energy Statistics 2012

    E-Print Network [OSTI]

    Levine, Mark

    2013-01-01T23:59:59.000Z

    Total Crude Oil Imports: 239 Mt World's Oil Consumption (consumption - Urban Statistical Difference Appendix 3: Energy Balance/China 2010 (cont’d) Mtce Crude Oilconsumption - Urban Other Statistical Difference Appendix 3: Energy Balance/China 2010 (cont’d) Physical Quantity Crude Oil

  11. Practical Statistics for the LHC

    E-Print Network [OSTI]

    Cranmer, Kyle

    2015-01-01T23:59:59.000Z

    This document is a pedagogical introduction to statistics for particle physics. Emphasis is placed on the terminology, concepts, and methods being used at the Large Hadron Collider. The document addresses both the statistical tests applied to a model of the data and the modeling itself.

  12. December 2000 A STATISTICAL TEST

    E-Print Network [OSTI]

    December 2000 A STATISTICAL TEST SUITE FOR RANDOM AND PSEUDORANDOM NUMBER GENERATORS challenges in authentication protocols. NIST Special Publication (SP) 800-22, A Statistical Test Suite testing of random number and pseudorandom number generators (RNGs and PRNGs) that may be used for many

  13. STATISTICAL FILTERING* John B. Moore~

    E-Print Network [OSTI]

    Moore, John Barratt

    noise signals. Theoretical developments in statistical filtering have been made side by side linkages will be made between these two major in filtering. in the developments In the classical approaches and the unwanted signals (noise) lie in another with possibly some overlap. In the statistical approach, the best

  14. Building statistical models by visualization

    E-Print Network [OSTI]

    Minka,Tom

    books · "The Elements of Graphing Data", William Cleveland, 2nd Ed. · "Visualizing Data", WilliamBuilding statistical models by visualization Tom Minka CMU Statistics Dept #12;Outline-scatterplot for unpaired data · Quantile of x = fraction of points

  15. NF-{kappa}B signaling is activated and confers resistance to apoptosis in three-dimensionally cultured EGFR-mutant lung adenocarcinoma cells

    SciTech Connect (OSTI)

    Sakuma, Yuji, E-mail: ysakuma@gancen.asahi.yokohama.jp [Molecular Pathology and Genetics Division, Kanagawa Cancer Center Research Institute, Yokohama (Japan)] [Molecular Pathology and Genetics Division, Kanagawa Cancer Center Research Institute, Yokohama (Japan); Yamazaki, Yukiko; Nakamura, Yoshiyasu; Yoshihara, Mitsuyo; Matsukuma, Shoichi; Koizume, Shiro; Miyagi, Yohei [Molecular Pathology and Genetics Division, Kanagawa Cancer Center Research Institute, Yokohama (Japan)] [Molecular Pathology and Genetics Division, Kanagawa Cancer Center Research Institute, Yokohama (Japan)

    2012-07-13T23:59:59.000Z

    Highlights: Black-Right-Pointing-Pointer EGFR-mutant cells in 3D culture resist EGFR inhibition compared with suspended cells. Black-Right-Pointing-Pointer Degradation of I{kappa}B and activation of NF-{kappa}B are observed in 3D-cultured cells. Black-Right-Pointing-Pointer Inhibiting NF-{kappa}B enhances the efficacy of the EGFR inhibitor in 3D-cultured cells. -- Abstract: Epidermal growth factor receptor (EGFR)-mutant lung adenocarcinoma cells in suspension undergo apoptosis to a greater extent than adherent cells in a monolayer when EGFR autophosphorylation is inhibited by EGFR tyrosine kinase inhibitors (TKIs). This suggests that cell adhesion to a culture dish may activate an anti-apoptotic signaling pathway other than the EGFR pathway. Since the microenvironment of cells cultured in a monolayer are substantially different to that of cells existing in three-dimension (3D) in vivo, we assessed whether two EGFR-mutant lung adenocarcinoma cell lines, HCC827 and H1975, were more resistant to EGFR TKI-induced apoptosis when cultured in a 3D extracellular matrix (ECM) as compared with in suspension. The ECM-adherent EGFR-mutant cells in 3D were significantly less sensitive to treatment with WZ4002, an EGFR TKI, than the suspended cells. Further, a marked degradation of I{kappa}B{alpha}, the inhibitor of nuclear factor (NF)-{kappa}B, was observed only in the 3D-cultured cells, leading to an increase in the activation of NF-{kappa}B. Moreover, the inhibition of NF-{kappa}B with pharmacological inhibitors enhanced EGFR TKI-induced apoptosis in 3D-cultured EGFR-mutant cells. These results suggest that inhibition of NF-{kappa}B signaling would render ECM-adherent EGFR-mutant lung adenocarcinoma cells in vivo more susceptible to EGFR TKI-induced cell death.

  16. BS in STATISTICS: Applied Statistics and Analytics Emphasis (695234) MAP Sheet Department of Statistics

    E-Print Network [OSTI]

    Olsen Jr., Dan R.

    of Statistics For students entering the degree program during the 2014­2015 curricular year. UNIVERSITY CORE Introduction to R Programming Stat 124 SAS Base Programming Skills Stat 223 Applied R Programming Stat 224 for Modeling Stat 497R Introduction to Statistical Research Stat 500 Business Career Essentials Stat 538

  17. Determination of the running coupling constant $?_s$ for Nf=2+1 QCD with the Schroedinger functional scheme

    E-Print Network [OSTI]

    Yusuke Taniguchi; for the PACS-CS collaboration

    2009-10-27T23:59:59.000Z

    We present an evaluation of the running coupling constant and the quark mass renormalization factor for $N_f=2+1$ QCD. The Schr\\"odinger functional scheme is used as the intermediate scheme to carry out non-perturbative running from the low energy region, where physical input is introduced, to deep in the high energy perturbative region, where conversion to the ${\\ovl{\\rm MS}}$ scheme is safely performed. For numerical simulations we adopted Iwasaki gauge action and non-perturbatively improved Wilson fermion action with the clover term. Seven renormalization scales are used to cover from low to high energy region and three lattice spacings to take the continuum limit at each scale. Physical inputs are introduced from the previous $N_f=2+1$ simulation of the CP-PACS/JL-QCD collaboration, which covered the up-down quark mass range heavier than $m_\\pi\\sim 500$ MeV, and that of PACS-CS collaboration for much lighter quark masses down to $m_\\pi=155$ MeV.

  18. Angiotensin II modulates interleukin-1{beta}-induced inflammatory gene expression in vascular smooth muscle cells via interfering with ERK-NF-{kappa}B crosstalk

    SciTech Connect (OSTI)

    Xu, Shanqin [Vascular Biology Unit, Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA (United States)] [Vascular Biology Unit, Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA (United States); Zhi, Hui [Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (United States)] [Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (United States); Hou, Xiuyun [Vascular Biology Unit, Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA (United States)] [Vascular Biology Unit, Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA (United States); Jiang, Bingbing, E-mail: bjiang1@rics.bwh.harvard.edu [Vascular Biology Unit, Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA (United States) [Vascular Biology Unit, Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA (United States); Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (United States)

    2011-07-08T23:59:59.000Z

    Highlights: {yields} We examine how angiotensin II modulates ERK-NF-{kappa}B crosstalk and gene expression. {yields} Angiotensin II suppresses IL-1{beta}-induced prolonged ERK and NF-{kappa}B activation. {yields} ERK-RSK1 signaling is required for IL-1{beta}-induced prolonged NF-{kappa}B activation. {yields} Angiotensin II modulates NF-{kappa}B responsive genes via regulating ERK-NF-{kappa}B crosstalk. {yields} ERK-NF-{kappa}B crosstalk is a novel mechanism regulating inflammatory gene expression. -- Abstract: Angiotensin II is implicated in cardiovascular diseases, which is associated with a role in increasing vascular inflammation. The present study investigated how angiotensin II modulates vascular inflammatory signaling and expression of inducible nitric oxide synthase (iNOS) and vascular cell adhesion molecule (VCAM)-1. In cultured rat aortic vascular smooth muscle cells (VSMCs), angiotensin II suppressed interleukin-1{beta}-induced prolonged phosphorylation of extracellular signal-regulated kinase (ERK) and ribosomal S6 kinase (RSK)-1, and nuclear translocation of nuclear factor (NF)-{kappa}B, leading to decreased iNOS but enhanced VCAM-1 expression, associated with an up-regulation of mitogen-activated protein kinase phosphatase-1 expression. Knock-down of RSK1 selectively down regulated interleukin-1{beta}-induced iNOS expression without influencing VCAM-1 expression. In vivo experiments showed that interleukin-1{beta}, iNOS, and VCAM-1 expression were detectable in the aortic arches of both wild-type and apolipoprotein E-deficient (ApoE{sup -/-}) mice. VCAM-1 and iNOS expression were higher in ApoE{sup -/-} than in wild type mouse aortic arches. Angiotensin II infusion (3.2 mg/kg/day, for 6 days, via subcutaneous osmotic pump) in ApoE{sup -/-} mice enhanced endothelial and adventitial VCAM-1 and iNOS expression, but reduced medial smooth muscle iNOS expression associated with reduced phosphorylation of ERK and RSK-1. These results indicate that angiotensin II can differentially modulate inflammatory gene expression in aortic smooth muscle cells through influencing ERK-NF-{kappa}B crosstalk, which may contribute to angiotensin II-induced inflammatory disorders related to cardiovascular diseases.

  19. FISHERY STATISTICS QF THE UNITED STATES

    E-Print Network [OSTI]

    I FISHERY STATISTICS QF THE UNITED STATES 1942 By A. W, ANDERSON and E. A. POWER STATISTICAL DIGEST Statistical Digest No. 11 FISHERY STATISTICS OF THE UNITED STATES 1942 BY A. W. ANDERSON and E. A. POWER. S. Government Printing Offic Washington 25, D. C. - Price 60 cents #12;Fishery Statistics

  20. Statistics in Linguistics Tutorial Just a sip. . .

    E-Print Network [OSTI]

    Fong, Sandiway

    Statistics in Linguistics Tutorial Just a sip. . . Mike Hammond Linguistics, U. of Arizona Statistics/Hammond ­ p.1/9 #12;Overview Statistics/Hammond ­ p.2/9 #12;Overview Are our data categorical? Statistics/Hammond ­ p.2/9 #12;Overview¡ Are our data categorical? ¡ Typological claims Statistics

  1. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES 1964 STATISTICAL DIGEST NO. 58 UNITED STATES DEPARTMENT Bureau of Commercial Fisheries, Donald L. McKernan, Director STATISTICAL DIGEST 58 FISHERY STATISTICS.S. Government Printing Office, Washington, D.C., 20402 - Price S2.50 (paper cover) #12;Fishery statistics

  2. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES 1963 STATISTICAL DIGEST NO. 57 UNITED STATES DEPARTMENT of Commercial Fisheries, Donald L. McKernan, Director STATISTICAL DIGEST 57 FISHERY STATISTICS OF THE UNITEDTernment Printing Office, Washington, D.C., 20402 - Price $2.25 (paper c #12;Fishery statistics of the United States

  3. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES 1962 STATISTICAL DIGEST NO. 56 UNITED STATES DEPARTMENT Fisheries, Donald L. McKernan, Director STATISTICAL DIGEST 56 FISHERY STATISTICS OF THE UNITED STATES 1962.S. Government Printing Office, Washington, D.C., 20402 - Price $2.25 (paper cover) #12;Fishery statistics

  4. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    Div,, . FISHERY STATISTICS OF THE UNITED STATES 1961 STATISTICAL DIGEST NO. 54 UNITED STATES, Donald L. MeKernan, Director STATISTICAL DIGEST 54 FISHERY STATISTICS OF THE UNITED STATES 1961 BY E. A, Washington, D.C. 20402 - Price $2 (paper cover) #12;Fishery statistics of the United States are compiled

  5. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES 1944 STATISTICAL DIGEST ISO. 16 Fish and Wildlife Sekvh Albert M. Day, Director Statistical Digest No. 16 FISHERY STATISTICS OF THE UNITED STATES 1944 BY A. W Statistics of the United States and Alaska are coiip i I ed and published annually to make available

  6. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    pa%Mv--. FISHERY STATISTICS OF THE UNITED STATES 1965 STATISTICAL DIGEST NO. 59 UNITED STATES, Commissioner Bureau of Commercial Fisheries, H. E. Crowther, Director STATISTICAL DIGEST 59 FISHERY STATISTICS.S. Government Printing Office Washington, D.C. 20402 - Price $4 (Paper Cover) #12;Fishery statistics

  7. FISHERY STATISTICS )F THE UNITED STATES

    E-Print Network [OSTI]

    SH 11 .A443X FISH FISHERY STATISTICS )F THE UNITED STATES ^M=^. STATISTICAL DIGEST NO. 36 #12. Farley, Director i]EL M. COHEN Statistical Digest 36 FISHERY STATISTICS OF THE UNITED STATES 1953 BY A. W;Fishery Statistics of the I'nited States and Alaska are compiled and published an- nually to make

  8. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES 1950 STATISTICAL DIGEST NO. 27 Fish and Wildlife ServiceKay, Secretary FISH AND WILDLIFE SERVICE, John L. Farley, Director Statistical Digest 27 FISHERY STATISTICS 25, DC. - - Price $2.00 (paper) #12;Fishery Statistics of the United States and A] aska are corapi

  9. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    SH 11 A443X FISH FISHERY STATISTICS OF THE UNITED STATES 1943 STATISTICAL DIGEST NO. 14 Sll \\M AND WILDLIFE SERVICE Albert M. Day, Director CAMEL M. COHEN Statistical Digest No. 14 FISHERY STATISTICS. - Price 75 cents #12;Fishery Statistics of the United States and Alaska are compiled and published

  10. Quantum particles from classical statistics

    E-Print Network [OSTI]

    C. Wetterich

    2010-02-11T23:59:59.000Z

    Quantum particles and classical particles are described in a common setting of classical statistical physics. The property of a particle being "classical" or "quantum" ceases to be a basic conceptual difference. The dynamics differs, however, between quantum and classical particles. We describe position, motion and correlations of a quantum particle in terms of observables in a classical statistical ensemble. On the other side, we also construct explicitly the quantum formalism with wave function and Hamiltonian for classical particles. For a suitable time evolution of the classical probabilities and a suitable choice of observables all features of a quantum particle in a potential can be derived from classical statistics, including interference and tunneling. Besides conceptual advances, the treatment of classical and quantum particles in a common formalism could lead to interesting cross-fertilization between classical statistics and quantum physics.

  11. Statistical mechanics of gene competition 

    E-Print Network [OSTI]

    Venegas-Ortiz, Juan; Ortiz, Juan Venegas

    2013-11-28T23:59:59.000Z

    Statistical mechanics has been applied to a wide range of systems in physics, biology, medicine and even anthropology. This theory has been recently used to model the complex biochemical processes of gene expression and ...

  12. Forensic Statistics: Ready for consumption?

    E-Print Network [OSTI]

    Gill, Richard D.

    in de rechtszaal. Stator. http://www.kennislink.nl/web/show?id=111865 #12;Everyday statistics · Intensive two-way interaction between statistician and subject-matter expert (client) Cyclic process of re

  13. Anyonic statistics with continuous variables

    E-Print Network [OSTI]

    Jing Zhang; Changde Xie; Kunchi Peng; Peter van Loock

    2008-10-30T23:59:59.000Z

    We describe a continuous-variable scheme for simulating the Kitaev lattice model and for detecting statistics of abelian anyons. The corresponding quantum optical implementation is solely based upon Gaussian resource states and Gaussian operations, hence allowing for a highly efficient creation, manipulation, and detection of anyons. This approach extends our understanding of the control and application of anyons and it leads to the possibility for experimental proof-of-principle demonstrations of anyonic statistics using continuous-variable systems.

  14. Faculty of Science Mathematics and Statistics

    E-Print Network [OSTI]

    Faculty of Science Mathematics and Statistics Mathematicians and statisticians use powerful mathematical, statistical and computational tools to solve both important theoretical problems and practical can pursue programs in mathematics, statistics, actuarial science, math and computer science

  15. American Statistical Association National Science Foundation

    E-Print Network [OSTI]

    Bermúdez, José Luis

    American Statistical Association National Science Foundation U.S. Census Bureau ASA American Statistical Association 732 North Washington Street Alexandria, VA 22314-1943 U.S. government and analysis, statistical methodology and computing, information and behavioral science, and geography

  16. STATISTICAL PHONE: 530.752.2361

    E-Print Network [OSTI]

    Wang, Jane-Ling

    . from 1995 to 1998, he developed further expertise in software develop- ment, statistical programming, analysis, programming, and interpretation. Since joining the Statistical Laboratory in 2005, he has R. Beran: multivariate regression, bootstrap meth- ods, statistics on manifolds, asymptotic theory P

  17. Apolipoprotein E inhibits osteoclast differentiation via regulation of c-Fos, NFATc1 and NF-?B

    SciTech Connect (OSTI)

    Kim, Woo-Shin; Kim, Hyung Joon; Lee, Zang Hee [Department of Cell and Developmental Biology, BK21 Program and Dental Research Institute, Seoul National University, 28 Yeongon-Dong, Chongno-Gu, Seoul 110-749 (Korea, Republic of); Lee, Youngkyun [Department of Biochemistry, School of Dentistry, Kyungpook National University, Daegu 700-422 (Korea, Republic of); Kim, Hong-Hee, E-mail: hhbkim@snu.ac.kr [Department of Cell and Developmental Biology, BK21 Program and Dental Research Institute, Seoul National University, 28 Yeongon-Dong, Chongno-Gu, Seoul 110-749 (Korea, Republic of)

    2013-02-15T23:59:59.000Z

    Apolipoprotein E (ApoE) plays a major role in the transport and metabolism of lipid. Other functions of ApoE include modulation of innate and adaptive immune responses. The expression of ApoE in osteoblasts and its relevance with bone formation have also been reported. However, the effect of ApoE on osteoclasts has not yet been examined. Here, we investigated the role of ApoE in osteoclast differentiation using bone marrow-derived macrophages (BMMs) and RAW264.7 cells. We found a down-regulation of ApoE gene expression during osteoclastic differentiation of those cells. Overexpression of ApoE in BMMs and RAW264.7 cells significantly blocked the induction of c-Fos and nuclear factor of activated T cell c1 (NFATc1), transcription factors critical for expression of osteoclast marker genes, by receptor activator of nuclear factor ?B ligand (RANKL), the osteoclast differentiation factor. ApoE inhibited osteoclast differentiation, as measured by decreased number of tartrate-resistant acid phosphatase (TRAP)-positive multinuclear cells (MNCs). In addition, ApoE reduced the expression of dendritic cell-specific transmembrane protein (DC-STAMP) and ATPase, H{sup +} transporting, lysosomal 38 kDa, V0 subunit d2 (ATP6v0d2), genes involved in cell–cell fusion during osteoclastogenesis. Knock-down of ApoE using a specific siRNA promoted the RANKL-mediated induction of osteoclast differentiation. While ApoE did not affect the activation of ERK, JNK, and p38 MAPK signaling pathways by RANKL, the phosphorylation of p65 trans-activation domain on serine 536 and transcription activity of NF-?B were reduced by ApoE overexpression. These findings suggest that ApoE plays an inhibitory role in osteoclast differentiation via the suppression of RANKL-dependent activation of NF-?B and induction of c-Fos and NFATc1. - Highlights: ? Apolipoprotein E (ApoE) significantly inhibited osteoclast differentiation and activation of NF-?B. ? ApoE decreased the induction of osteoclast marker genes such as c-Fos, NFATc1, TRAP, DC-STAMP and Cathepsin K. ? ApoE reduced number of TRAP-positive multinuclear cells. ? Exogenous ApoE inhibits osteoclast formation by reduction of crucial factor of osteoclast differentiation. ? knock-down of ApoE promoted the RANKL-mediated induction of osteoclast differentiation.

  18. 1.0 What is Statistics? 1.1 What is Mathematical Statistics? Random Data Basic Ideas in Statistics 1.2 Fundamental Con Mathematical Statistics

    E-Print Network [OSTI]

    Zhang, Li-Xin

    §1.0 What is Statistics? §1.1 What is Mathematical Statistics? Random Data Basic Ideas in Statistics §1.2 Fundamental Con Mathematical Statistics Zhang, Lixin and Dai, Jialing Course Website: www.math.zju.edu.cn/zlx/teaching.htm #12;§1.0 What is Statistics? §1.1 What is Mathematical Statistics? Random Data Basic Ideas

  19. GRP94/gp96 Elicits ERK Activation in Murine Macrophages A ROLE FOR ENDOTOXIN CONTAMINATION IN NF-B ACTIVATION AND NITRIC OXIDE PRODUCTION*

    E-Print Network [OSTI]

    Nicchitta, Chris

    GRP94/gp96 Elicits ERK Activation in Murine Macrophages A ROLE FOR ENDOTOXIN CONTAMINATION IN NF- B signaling and ni- tric oxide production, as well as the MAP kinase p38, JNK, and ERK signaling cascades a marked increase in ERK phosphorylation at protein concentrations as low as 2 g/ml. These results

  20. Differential Effects of ?-catenin and NF-?B Interplay in the Regulation of Cell Proliferation, Inflammation and Tumorigenesis in Response to Bacterial Infection

    E-Print Network [OSTI]

    Chandrakesan, Parthasarathy; Jakkula, Laxmi Uma Maheswar Rao; Ahmed, Ishfaq; Roy, Badal; Anant, Shrikant; Umar, Shahid

    2013-11-21T23:59:59.000Z

    Both ?-catenin and NF-?B have been implicated in our laboratory as candidate factors in driving proliferation in an in vivo model of Citrobacter rodentium (CR)-induced colonic crypt hyper-proliferation and hyperplasia. Herein, we test the hypothesis...

  1. Moore honored with American Statistical Association award

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    American Statistical Association Award Moore honored with American Statistical Association award Lisa Moore is the recipient of the 2013 Don Owen Award presented by the American...

  2. DEPARTMENT OF STATISTICS Hilary Term 2007 MSc and Diploma in Applied Statistics

    E-Print Network [OSTI]

    Goldschmidt, Christina

    DEPARTMENT OF STATISTICS ­ Hilary Term 2007 MSc and Diploma in Applied Statistics DAY HOUR TITLE LECTURER PLACE MON 12-1 Time Series (wks 1-4) Dr Laws Statistics 12-1 MCMC and Applied Bayesian Statistics (wks 5-7) Professor Reinert Statistics 2-3 Statistical Data Mining (wks 1-8) Dr Nicholls Maths

  3. Spontaneous transition of core radial electric field driven by magnetic islands in the H-1NF heliac

    SciTech Connect (OSTI)

    Kumar, S. T. A. [University of Wisconsin, Madison; Blackwell, B. D. [Australian National University, Canberra, Australia; Howard, J. [Australian National University, Canberra, Australia; Harris, J. H. [Oak Ridge National Laboratory (ORNL)

    2011-01-01T23:59:59.000Z

    This paper reports an experimental observation of spontaneous transition of the core radial electric field to a large positive value (E(r) similar to 5 kV m(-1)), with a strong electric-field shear (similar to 700 kV m(-2)) in a low temperature (T(e) similar to 10 eV) radio frequency generated argon plasma in the H-1NF heliac stellarator. The transition, which seems to be driven by a spontaneous excitation of m = 2 magnetic islands near the core, is associated with a localized increase in the plasma density and excitation of coherent low frequency (similar to 3 kHz) oscillations possibly due to unstable E(r) shear driven modes. Evidence suggests development of the core electron-root scenario, which previously has been observed only at high temperature electron cyclotron heated plasmas.

  4. Absolute frequency measurements of 85Rb nF7/2 Rydberg states using purely optical detection

    E-Print Network [OSTI]

    L. A. M. Johnson; H. O. Majeed; B. Sanguinetti; Th. Becker; B. T. H. Varcoe

    2010-02-16T23:59:59.000Z

    A three-step laser excitation scheme is used to make absolute frequency measurements of highly excited nF7/2 Rydberg states in 85Rb for principal quantum numbers n=33-100. This work demonstrates the first absolute frequency measurements of rubidium Rydberg levels using a purely optical detection scheme. The Rydberg states are excited in a heated Rb vapour cell and Doppler free signals are detected via purely optical means. All of the frequency measurements are made using a wavemeter which is calibrated against a GPS disciplined self-referenced optical frequency comb. We find that the measured levels have a very high frequency stability, and are especially robust to electric fields. The apparatus has allowed measurements of the states to an accuracy of 8.0MHz. The new measurements are analysed by extracting the modified Rydberg-Ritz series parameters.

  5. Magnetic susceptibility and equation of state of N_f = 2+1 QCD with physical quark masses

    E-Print Network [OSTI]

    Claudio Bonati; Massimo D'Elia; Marco Mariti; Francesco Negro; Francesco Sanfilippo

    2014-05-13T23:59:59.000Z

    We determine the free energy of strongly interacting matter as a function of an applied constant and uniform magnetic field. We consider N_f = 2+1 QCD with physical quark masses, discretized on a lattice by stout improved staggered fermions and a tree level improved Symanzik pure gauge action, and explore three different lattice spacings. For magnetic fields of the order of those produced in non-central heavy ion collisions (eB ~ 0.1 GeV^2) strongly interacting matter behaves like a medium with a linear response, and is paramagnetic both above and below the deconfinement transition, with a susceptibility which steeply rises in the deconfined phase. We compute the equation of state, showing that the relative increase in the pressure due to the magnetic field gets larger around the transition, and of the order of 10 % for eB ~ 0.1 GeV^2.

  6. Metastatic function of BMP-2 in gastric cancer cells: The role of PI3K/AKT, MAPK, the NF-{kappa}B pathway, and MMP-9 expression

    SciTech Connect (OSTI)

    Kang, Myoung Hee [Graduate School of Medicine, Korea University College of Medicine, Korea University, Seoul 136-705 (Korea, Republic of)] [Graduate School of Medicine, Korea University College of Medicine, Korea University, Seoul 136-705 (Korea, Republic of); Oh, Sang Cheul [Division of Oncology/Hematology, Department of Internal Medicine, Korea University College of Medicine, Korea University, Seoul 136-705 (Korea, Republic of)] [Division of Oncology/Hematology, Department of Internal Medicine, Korea University College of Medicine, Korea University, Seoul 136-705 (Korea, Republic of); Lee, Hyun Joo [Department of Pathology, Korea University College of Medicine, Korea University, Seoul 136-705 (Korea, Republic of)] [Department of Pathology, Korea University College of Medicine, Korea University, Seoul 136-705 (Korea, Republic of); Kang, Han Na; Kim, Jung Lim [Graduate School of Medicine, Korea University College of Medicine, Korea University, Seoul 136-705 (Korea, Republic of)] [Graduate School of Medicine, Korea University College of Medicine, Korea University, Seoul 136-705 (Korea, Republic of); Kim, Jun Suk [Division of Oncology/Hematology, Department of Internal Medicine, Korea University College of Medicine, Korea University, Seoul 136-705 (Korea, Republic of)] [Division of Oncology/Hematology, Department of Internal Medicine, Korea University College of Medicine, Korea University, Seoul 136-705 (Korea, Republic of); Yoo, Young A., E-mail: ydanbi@korea.ac.kr [Brain Korea 21 Program for Biomedical Science, Korea University College of Medicine, Korea University, Seoul 136-705 (Korea, Republic of)

    2011-07-15T23:59:59.000Z

    Bone morphogenetic proteins (BMPs) have been implicated in tumorigenesis and metastatic progression in various types of cancer cells, but the role and cellular mechanism in the invasive phenotype of gastric cancer cells is not known. Herein, we determined the roles of phosphoinositide 3-kinase (PI3K)/AKT, extracellular signal-regulated protein kinase (ERK), nuclear factor (NF)-{kappa}B, and matrix metalloproteinase (MMP) expression in BMP-2-mediated metastatic function in gastric cancer. We found that stimulation of BMP-2 in gastric cancer cells enhanced the phosphorylation of AKT and ERK. Accompanying activation of AKT and ERK kinase, BMP-2 also enhanced phosphorylation/degradation of I{kappa}B{alpha} and the nuclear translocation/activation of NF-{kappa}B. Interestingly, blockade of PI3K/AKT and ERK signaling using LY294002 and PD98059, respectively, significantly inhibited BMP-2-induced motility and invasiveness in association with the activation of NF-{kappa}B. Furthermore, BMP-2-induced MMP-9 expression and enzymatic activity was also significantly blocked by treatment with PI3K/AKT, ERK, or NF-{kappa}B inhibitors. Immunohistochemistry staining of 178 gastric tumor biopsies indicated that expression of BMP-2 and MMP-9 had a significant positive correlation with lymph node metastasis and a poor prognosis. These results indicate that the BMP-2 signaling pathway enhances tumor metastasis in gastric cancer by sequential activation of the PI3K/AKT or MAPK pathway followed by the induction of NF-{kappa}B and MMP-9 activity, indicating that BMP-2 has the potential to be a therapeutic molecular target to decrease metastasis.

  7. STATISTICS IN MEDICINE Statist. Med. 2009; 28:34543466

    E-Print Network [OSTI]

    McLachlan, Geoff

    of Western Australia, Perth, Australia 4Centre for Statistics, University of Queensland, Brisbane, Australia, Curtin University of Technology, GPO Box U 1987, Perth, WA 6845, Australia 2Department of Management Research Institute, Curtin University of Technology, GPO Box U 1987, Perth, WA 6845, Australia. E

  8. STATISTICS IN MEDICINE Statist. Med. 18, 32213234 (1999)

    E-Print Network [OSTI]

    Gelman, Andrew

    1999-01-01T23:59:59.000Z

    States. Much of the variation in observed cancer death rates by county is attributable to statistical to have extremely high (or low) cancer rates when compared to typical counties in the United States. Thus to keep a speciÿc example in mind. Consider the mapping of cancer mortality rates by county in the United

  9. STAT 639v: Topics in Statistics Statistical Computing

    E-Print Network [OSTI]

    Petris, Giovanni

    , or by appointment. Textbooks: Braun and Murdoch (2007), A First Course in Statistical Programming with R, Cambridge roughly every two or three weeks. Outline syllabus: After learning the R programming language, we, the bootstrap. Computing: The computer language we will be using is R. The latest version of R is installed

  10. advanced statistical methods: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    binomial, Poisson Gordon, Geoffrey J. 7 Statistics 36-756: Advanced Statistics II Syllabus: Fall, 2006 Mathematics Websites Summary: Statistics 36-756: Advanced Statistics II...

  11. Department of Mathematics and Statistics The Department of Mathematics and Statistics invites applications for a tenure-track position in Statistics. The

    E-Print Network [OSTI]

    Kambhampati, Patanjali

    Department of Mathematics and Statistics ___________________________ The Department of Mathematics and Statistics invites applications for a tenure-track position in Statistics. The Department welcomes or complex data settings, including high dimensional regression, computational statistics and statistical

  12. FISHERY STATISTICS F THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS »F THE UNITED STATES ^ 1954 ,M^,. 'M' . ' J*"'',-,'i''' ' STATISTICAL DIGEST NO DEPARTMENT OF THE INTERIOR, Fred A. Seaton, Secretary FISH AND WILDLIFE SERVICE PANIELM. COHEN Statistical Digest 39 FISHERY STATISTICS OF THE UNITED STATES 1954 BY A. W. ANDERSON and E. A. POWER UNITED STATES

  13. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES I 1952 .^£^ STATISTICAL DIGEST NO. 34 Fish and Wildlife McKay, Secretary FISH AND WILDLIFE SERVICE, John L. Farley, Director -iJ^EUW^ .COHEN Statistical Digest 34 FISHERY STATISTICS OF THE UNITED STATES 1952 BY A. W. ANDERSON and E. A. POWER UNITED STATES

  14. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES 1966 STATISTICAL DIGEST NO. 60 UNITED STATES DEPARTMENT OF THE INTERIOR U.S. FISH AND WILDLIFE SERVICE Bureau of Commercial Fisheries STATISTICAL DIGEST 60 FISHERY STATISTICS OF THE UNITED STATES 1966 BY Charles H. Lyles PUBLISHED BY BUREAU OF COMMERCIAL FISHERIES

  15. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES 1959 ^mmi STATISTICAL DIGEST NO. 51 UNITED STATES DEPARTMl of Commercial Fisheries, Donald L. McKernan, Director jPANlELM COHEN FISH AND WILDLIFE SERVICE STATISTICAL DIGEST 51 FISHERY STATISTICS OF THE UNITED STATES 1959 BY E. A. POWER PUBLISHED BY BUREAU OF COMMERCIAL

  16. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES 1946 STATISTICAL DIGEST NO, 19 Fish and Wildlike Sekvice L. Chapman, Secretary FISH AND WILDLIFE SERVICE Albert M. Day, Director Statistical Digest 19 FISHERY STATISTICS OF THE UNITED STATES 1946 BY A. W. ANDERSON and E. A. POWER UNITED STATES GOVERNMENT

  17. The University of Connecticut Department of Statistics

    E-Print Network [OSTI]

    Blei, Ron

    1 The University of Connecticut Department of Statistics Graduate Program Founded in 1963, the Department is one of the major statistics departments in the Northeast and has national and international and statistics, spanning virtually all modern areas of statistical applications. Graduate education has been

  18. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES SH 11 A443X FISH 1948 STATISTICAL DIGEST NO. 22 Fish OF THE INTERIOR, Oscar L. Chapman, Secretary FISH AND WILDLIFE SERVICE, Albert M. Day, Director Statistical Digest 22 FISHERY STATISTICS OF THE UNITED STATES 1948 BY A. W. ANDERSON and E. A. POWER UNITED STATES

  19. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES 1945 STATISTICAL DIGEST NO, 18 United States Dejtartment. Krug, Secretary FISH AND WILDLIFE SERVICE Albert M. Day, Director Statistical Digest 18 FISHERY STATISTICS OF THE UNITED STATES 1945 BY A. W. ANDERSON and E. A. POWER UNITED STATES GOVERNMENT PRINTING

  20. FISHERY STATISTICS OF THE UNITED STATES

    E-Print Network [OSTI]

    FISHERY STATISTICS OF THE UNITED STATES I 1947 cf^^v'^ml STATISTICAL DIGEST NO. 21 Fish Oscar L. Chapman, Secretary FISH AND WILDLIFE SERVICE Albert M. Day, Director Statistical Digest 21 PI^j^IELW' , COHEN FISHERY STATISTICS OF THE UNITED STATES 1947 BY A. W. ANDERSON and E. A. POWER UNITED STATES

  1. C. Shane Reese Department of Statistics

    E-Print Network [OSTI]

    Reese, Shane

    of Statistics Honored Faculty Member 2001 Journal of the American Statistical Association Applications and Case, SRCOS/ASA Research Conference A#liations American Statistical Association, Biometric Society (WNAR), IMS­present Associate Editor, Journal of the American Statistical Association 2006­2008 Vice­chair, ASA

  2. DEPARTMENT OF STATISTICS ANNUAL REPORT 2006

    E-Print Network [OSTI]

    Goodman, James R.

    Waksberg Award from the American Statistical Association and the Statistical Society of Canada for his work Statistical Association, was held at Sky City in Auckland on July 3 to 6 with David Scott as ChairDEPARTMENT OF STATISTICS ANNUAL REPORT 2006 Highlights Last year I highlighted the fact that Ross

  3. LIDIA REJTO Statistics Program, Department of FREC

    E-Print Network [OSTI]

    Rejtõ, Lídia

    L´IDIA REJTO Statistics Program, Department of FREC CANR, University of Delaware 214 Townsend Hall package. Familiar with statistical softwares R, S-Plus, BMDP, SAS, MINITAB. PROFESSIONAL EXPERIENCES Permanent Position: Full Professor, Director of Statistical Laboratory, Statistics Program, Department

  4. Purdue Agriculture Annual Statistical Report

    E-Print Network [OSTI]

    Purdue Agriculture Research Works Annual Statistical Report 2005-2006 Purdue AGrICuLTure Read the full report on the Web www.ag.purdue.edu/arp/stat_report_05-06 #12;Purdue AGrICuLTure Purdue Agriculture Research Works Here's why. We are riding the wave of revolutionary changes brought about

  5. Statistics Colloquium Dr. Noel Cadigan

    E-Print Network [OSTI]

    Oyet, Alwell

    :00a.m., HH-3026 Statistical problems to address for some NL fish stocks when deriving Maximum prescribed actions should occur when stock size or fishing mortality rates (F) exceed the reference points. This is the biomass that should result in the long term when fishing at Fmsy ­ the harvest rate that maximizes long

  6. Statistics in Practice Forensic Science

    E-Print Network [OSTI]

    Lucy, David

    ". · Greater use of trace evidence (paint/glass/fibres). · DNA revolution. The rise of DNA was coincident: · Trace evidence (glass/paint/fibres) being treated statistically. · More evidence types: · common partner Sally Rose. · He picked up a champagne bottle and struck her on the head. · Rose died at the scene

  7. Statistical mechanics of the vacuum

    E-Print Network [OSTI]

    Christian Beck

    2012-03-01T23:59:59.000Z

    The vacuum is full of virtual particles which exist for short moments of time. In this paper we construct a chaotic model of vacuum fluctuations associated with a fundamental entropic field that generates an arrow of time. The dynamics can be physically interpreted in terms of fluctuating virtual momenta. This model leads to a generalized statistical mechanics that distinguishes fundamental constants of nature.

  8. Introduction to statistical models and non-extensive statistics

    E-Print Network [OSTI]

    T. S. Biro

    2005-07-27T23:59:59.000Z

    Quark matter is being expected to be found in heavy ion collisions on the basis of calculations in the framework of traditional, extensive thermodynamics. Recently a non-extensive generalization of the thermodynamics is emerging in the theoretical research. We review here some basic concepts in statistics, kinetic theory and thermodynamics, in particular those encountered in non-extensive thermodynamics. This offers an introduction into the theoretical basis of considering non-extensive parton kinetics for describing the hadronization of quark matter.

  9. Trap cultures reveal higher species richness of arbuscular mycorrhizal fungi in comparison to soil samples in the Phoenix metropolitan area.Arbuscular mycorrhizal fungal and dark septate endophytes colonization of plant roots from urban desert preserves a

    E-Print Network [OSTI]

    Hall, Sharon J.

    samples in the Phoenix metropolitan area.Arbuscular mycorrhizal fungal and dark septate endophytes mycorrhizal fungal and dark septate endophytes colonization of plant roots from urban desert preserves (Brundett 1999). Dark septate endophytes (DSE) are another type of root colonizing fungi mainly classified

  10. MANCHESTER METROPOLITAN Financial Statements

    E-Print Network [OSTI]

    (includes share of associated company's result) (199,979) (185,386) Impairment on properties in an impairment charge of £7.7m The University has during the past year been planning the implementation of six seven campus areas down to three and will ensure the University has a sustainable estate for the future

  11. Lubbock Metropolitan Transportation Plan

    E-Print Network [OSTI]

    Lubbock Metropolitan Planning Organization

    2007-09-18T23:59:59.000Z

    for Users (SAFETEA-LU) and its predecessors, the Transportation Equity Act for the 21st Century (TEA-21) and the Intermodal Surface Transportation Efficiency Act (ISTEA) of 1991, specified the transportation systems on which certain federal funds can... in Chapter 5 ? Streets and Highways; Chapter 6 ? Public Transportation; Chapter 7 ? Bicycle and Pedestrian Plan; Chapter 8 ? Lubbock International Airport and Chapter 9 ? Railroads and Trucking. Federally funded transit projects were developed...

  12. Manchester Metropolitan University Sustainability

    E-Print Network [OSTI]

    key technologies such as rainwater harvesting and grey water systems to reduce our water usage & Healthy Buildings Water savings · We've reduced our yearly water consumption by 12.1%. · We've utilised of the most visibly sustainable in Manchester city centre. 2,592,000 Ltr Water Management Biodiversity 39 #12

  13. Metropolitan problems in Texas

    E-Print Network [OSTI]

    Pearson, William Morris

    1965-01-01T23:59:59.000Z

    , the fifty state govern- ments, and 56, 507 local governments other than school districts: 3)043 counties, 17, 997 municipalities, 17, 144 townships, and. 18, 323 special districts. The average number of governmental units per state was 1, 825. However... Counties Municipalities Townships and towns School districts Special districts Total 1 50 17, 997 17, 144 34, 678 18, 323 91, 236 1 50 3)050 17)251 17, 198 50, 454 14, 424 102, 392 1 50 3) 052 16, 807 17)202 67, 355 12, 340 116...

  14. Parallel contingency statistics with Titan.

    SciTech Connect (OSTI)

    Thompson, David C.; Pebay, Philippe Pierre

    2009-09-01T23:59:59.000Z

    This report summarizes existing statistical engines in VTK/Titan and presents the recently parallelized contingency statistics engine. It is a sequel to [PT08] and [BPRT09] which studied the parallel descriptive, correlative, multi-correlative, and principal component analysis engines. The ease of use of this new parallel engines is illustrated by the means of C++ code snippets. Furthermore, this report justifies the design of these engines with parallel scalability in mind; however, the very nature of contingency tables prevent this new engine from exhibiting optimal parallel speed-up as the aforementioned engines do. This report therefore discusses the design trade-offs we made and study performance with up to 200 processors.

  15. STATISTICAL MECHANICS PRACTICE EXAM 2005

    E-Print Network [OSTI]

    Dorlas, Teunis C.

    STATISTICAL MECHANICS PRACTICE EXAM 2005 Time allotted: 3 hours for 5 questions. 1. (i) Give density of a system of independent spins si = ±1 with energy levels given by E(s1, . . . , sN ) = -H N i=1 si. 2. (i) Derive the expression f() = - 1 ln eJ cosh H + e2J sinh2 H + e-2J for the free energy

  16. Parallel auto-correlative statistics with VTK.

    SciTech Connect (OSTI)

    Pebay, Philippe Pierre [Kitware, France; Bennett, Janine Camille

    2013-08-01T23:59:59.000Z

    This report summarizes existing statistical engines in VTK and presents both the serial and parallel auto-correlative statistics engines. It is a sequel to [PT08, BPRT09b, PT09, BPT09, PT10] which studied the parallel descriptive, correlative, multi-correlative, principal component analysis, contingency, k-means, and order statistics engines. The ease of use of the new parallel auto-correlative statistics engine is illustrated by the means of C++ code snippets and algorithm verification is provided. This report justifies the design of the statistics engines with parallel scalability in mind, and provides scalability and speed-up analysis results for the autocorrelative statistics engine.

  17. Characterization of Fine Particulate Matter (PM) and Secondary PM Precursor Gases in the Mexico City Metropolitan Area

    SciTech Connect (OSTI)

    Luisa T. Molina, Rainer Volkamer, Benjamin de Foy, Wenfang Lei, Miguel Zavala, Erik Velasco; Mario J. Molina

    2008-10-31T23:59:59.000Z

    This project was one of three collaborating grants funded by DOE/ASP to characterize the fine particulate matter (PM) and secondary PM precursors in the Mexico City Metropolitan Area (MCMA) during the MILAGRO Campaign. The overall effort of MCMA-2006, one of the four components, focused on i) examination of the primary emissions of fine particles and precursor gases leading to photochemical production of atmospheric oxidants and secondary aerosol particles; ii) measurement and analysis of secondary oxidants and secondary fine PM production, with particular emphasis on secondary organic aerosol (SOA), and iii) evaluation of the photochemical and meteorological processes characteristic of the Mexico City Basin. The collaborative teams pursued the goals through three main tasks: i) analyses of fine PM and secondary PM precursor gaseous species data taken during the MCMA-2002/2003 campaigns and preparation of publications; ii) planning of the MILAGRO Campaign and deployment of the instrument around the MCMA; and iii) analysis of MCMA-2006 data and publication preparation. The measurement phase of the MILAGRO Campaign was successfully completed in March 2006 with excellent participation from the international scientific community and outstanding cooperation from the Mexican government agencies and institutions. The project reported here was led by the Massachusetts Institute of Technology/Molina Center for Energy and the Environment (MIT/MCE2) team and coordinated with DOE/ASP-funded collaborators at Aerodyne Research Inc., University of Colorado at Boulder and Montana State University. Currently 24 papers documenting the findings from this project have been published. The results from the project have improved significantly our understanding of the meteorological and photochemical processes contributing to the formation of ozone, secondary aerosols and other pollutants. Key findings from the MCMA-2003 include a vastly improved speciated emissions inventory from on-road vehicles: the MCMA motor vehicles produce abundant amounts of primary PM, elemental carbon, particle-bound polycyclic aromatic hydrocarbons, carbon monoxide and a wide range of air toxics; the feasibility of using eddy covariance techniques to measure fluxes of volatile organic compounds in an urban core and a valuable tool for validating local emissions inventory; a much better understanding of the sources and atmospheric loadings of volatile organic compounds; the first spectroscopic detection of glyoxal in the atmosphere; a unique analysis of the high fraction of ambient formaldehyde from primary emission sources; characterization of ozone formation and its sensitivity to VOCs and NOx; a much more extensive knowledge of the composition, size distribution and atmospheric mass loadings of both primary and secondary fine PM, including the fact that the rate of MCMA SOA production greatly exceeded that predicted by current atmospheric models; evaluations of significant errors that can arise from standard air quality monitors for O3 and NO2; and the implementation of an innovative Markov Chain Monte Carlo method for inorganic aerosol modeling as a powerful tool to analyze aerosol data and predict gas phase concentrations where these are unavailable. During the MILAGRO Campaign the collaborative team utilized a combination of central fixed sites and a mobile laboratory deployed throughout the MCMA to representative urban and boundary sites to measure trace gases and fine particles. Analysis of the extensive 2006 data sets has confirmed the key findings from MCMA-2002/2003; additionally MCMA-2006 provided more detailed gas and aerosol chemistry and wider regional scale coverage. Key results include an updated 2006 emissions inventory; extension of the flux system to measure fluxes of fine particles; better understanding of the sources and apportionment of aerosols, including contribution from biomass burning and industrial sources; a comprehensive evaluation of metal containing particles in a complex urban environment; identification of a close correlation between

  18. Inhibition of inflammatory mediators contributes to the anti-inflammatory activity of KYKZL-1 via MAPK and NF-?B pathway

    SciTech Connect (OSTI)

    Xu, Guang-Lin [Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing (China); Department of Pharmacology, University of Michigan, Ann Arbor (United States); Du, Yi-Fang; Cheng, Jing; Huan, Lin [Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing (China); Chen, Shi-Cui [Jinhu Food and Drug Administration, Jiangsu (China); Wei, Shao-Hua [College of Chemistry and Materials Science, Nanjing Normal University, Nanjing (China); Gong, Zhu-Nan, E-mail: biopharmacology@126.com [Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing (China); Cai, Jie; Qiu, Ting; Wu, Hao; Sun, Ting [Jiangsu Key Laboratory for Molecular and Medical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing (China); Ao, Gui-Zhen [Department of Medicinal Chemistry, School of Pharmacy, Soochow University, Jiangsu (China)

    2013-10-01T23:59:59.000Z

    KYKZL-1, a newly synthesized compound with COX/5-LOX dual inhibition, was subjected to the anti-inflammatory activity test focusing on its modulation of inflammatory mediators as well as intracellular MAPK and NF-?B signaling pathways. In acute ear edema model, pretreatment with KYKZL-1 (p.o.) dose-dependently inhibited the xylene-induced ear edema in mice with a higher inhibition than diclofenac. In a three-day TPA-induced inflammation, KYKZL-1 also showed significant anti-inflammatory activity with inhibition ranging between 20% and 64%. In gastric lesion test, KYKZL-1 elicited markedly fewer stomach lesions with a low index of ulcer as compared to diclofenac in rats. In further studies, KYKZL-1 was found to significantly inhibit the production of NO, PGE{sub 2}, LTB{sub 4} in LPS challenged RAW264.7, which is parallel to its attenuation of the expression of iNOS, COX-2, 5-LOX mRNAs or proteins and inhibition of phosphorylation of p38 and ERK MAPKs and activation of NF-?B. Taken together, our data indicate that KYKZL-1 comprises dual inhibition of COX and 5-LOX and exerts an obvious anti-inflammatory activity with an enhanced gastric safety profile via simultaneous inhibition of phosphorylation of p38 and ERK MAPKs and activation of NF-?B. - Highlights: • KYKZL-1 is designed to exhibit COX/5-LOX dual inhibition. • KYKZL-1 inhibits NO, PGE{sub 2} and LTB{sub 4} and iNOS, COX-2 and 5-LOX mRNAs and MAPKs. • KYKZL-1 inhibits phosphorylation of MAPKs. • KYKZL-1 inactivates NF-?B pathway.

  19. September 12, 2013 THE FLORIDA STATE UNIVERSITY DEPARTMENT OF STATISTICS

    E-Print Network [OSTI]

    Shepp, Larry

    September 12, 2013 THE FLORIDA STATE UNIVERSITY DEPARTMENT OF STATISTICS ASSISTANT PROFESSOR POSITION IN STATISTICS, BIOSTATISTICS, OR COMPUTATIONAL STATISTICS (TENURE-TRACK) The Department of Statistics at Florida State University invites applications for a tenure-track position in statistics

  20. Carbachol ameliorates lipopolysaccharide-induced intestinal epithelial tight junction damage by down-regulating NF-{kappa}{beta} and myosin light-chain kinase pathways

    SciTech Connect (OSTI)

    Zhang, Ying [Department of Anesthesia, Critical Care Medicine and Emergency Medicine Center, Zhongnan Hospital, Wuhan University, Wuhan 430071, Hubei Province, People's Republic of China (China)] [Department of Anesthesia, Critical Care Medicine and Emergency Medicine Center, Zhongnan Hospital, Wuhan University, Wuhan 430071, Hubei Province, People's Republic of China (China); Li, Jianguo, E-mail: 2010lijianguo@sina.cn [Department of Anesthesia, Critical Care Medicine and Emergency Medicine Center, Zhongnan Hospital, Wuhan University, Wuhan 430071, Hubei Province, People's Republic of China (China)] [Department of Anesthesia, Critical Care Medicine and Emergency Medicine Center, Zhongnan Hospital, Wuhan University, Wuhan 430071, Hubei Province, People's Republic of China (China)

    2012-11-16T23:59:59.000Z

    Highlights: Black-Right-Pointing-Pointer Carbachol reduced the lipopolysaccharide-induced intestinal barrier breakdown. Black-Right-Pointing-Pointer Carbachol ameliorated the lipopolysaccharide-induced ileal tight junction damage. Black-Right-Pointing-Pointer Carbachol prevented the LPS-induced NF-{kappa}{beta} and myosin light-chain kinase activation. Black-Right-Pointing-Pointer Carbachol exerted its beneficial effects in an {alpha}7 nicotinic receptor-dependent manner. -- Abstract: Carbachol is a cholinergic agonist that protects the intestines after trauma or burn injury. The present study determines the beneficial effects of carbachol and the mechanisms by which it ameliorates the lipopolysaccharide (LPS)-induced intestinal barrier breakdown. Rats were injected intraperitoneally with 10 mg/kg LPS. Results showed that the gut barrier permeability was reduced, the ultrastructural disruption of tight junctions (TJs) was prevented, the redistribution of zonula occludens-1 and claudin-2 proteins was partially reversed, and the nuclear factor-kappa beta (NF-{kappa}{beta}) and myosin light-chain kinase (MLCK) activation in the intestinal epithelium were suppressed after carbachol administration in LPS-exposed rats. Pretreatment with the {alpha}7 nicotinic acetylcholine receptor ({alpha}7nAchR) antagonist {alpha}-bungarotoxin blocked the protective action of carbachol. These results suggested that carbachol treatment can protect LPS-induced intestinal barrier dysfunction. Carbachol exerts its beneficial effect on the amelioration of the TJ damage by inhibiting the NF-{kappa}{beta} and MLCK pathways in an {alpha}7nAchR-dependent manner.

  1. American Statistical Association Names Fellows for 2010 ALEXANDRIA VA (PRWEB) MAY 20, 2010 The American Statistical Association (ASA), the

    E-Print Network [OSTI]

    Ponce, V. Miguel

    American Statistical Association Names Fellows for 2010 ALEXANDRIA VA (PRWEB) MAY 20, 2010 ­ The American Statistical Association (ASA), the nation's preeminent professional statistical society, today the American Statistical Association The American Statistical Association (ASA), a scientific and educational

  2. Broken Valence Chiral Symmetry and Chiral Polarization of Dirac Spectrum in N$_f$=12 QCD at Small Quark Mass

    E-Print Network [OSTI]

    Andrei Alexandru; Ivan Horváth

    2014-12-04T23:59:59.000Z

    The validity of recently proposed equivalence between valence spontaneous chiral symmetry breaking (vSChSB) and chiral polarization of low energy Dirac spectrum (ChP) in SU(3) gauge theory, is examined for the case of twelve mass-degenerate fundamental quark flavors. We find that the vSChSB-ChP correspondence holds for regularized systems studied. Moreover, our results suggest that vSChSB occurs in two qualitatively different circumstances: there is a quark mass $m_c$ such that for $m > m_c$ the mode condensing Dirac spectrum exhibits standard monotonically increasing density, while for $m_{ch} < m < m_c$ the peak around zero separates from the bulk of the spectrum, with density showing a pronounced depletion at intermediate scales. Valence chiral symmetry restoration may occur at yet smaller masses $m < m_{ch}$, but this has not yet been seen by overlap valence probe, leaving the $m_{ch}=0$ possibility open. The latter option could place massless N$_f$=12 theory outside of conformal window. Anomalous behavior of overlap Dirac spectrum for $m_{ch} < m < m_c$ is qualitatively similar to one observed previously in zero and few-flavor theories as an effect of thermal agitation.

  3. Up, down, strange and charm quark masses with Nf = 2+1+1 twisted mass lattice QCD

    E-Print Network [OSTI]

    N. Carrasco; A. Deuzeman; P. Dimopoulos; R. Frezzotti; V. Gimenez; G. Herdoiza; P. Lami; V. Lubicz; D. Palao; E. Picca; S. Recker; L. Riggio; G. C. Rossi; F. Sanfilippo; L. Scorzato; S. Simula; C. Tarantino; C. Urbach; U. Wenger

    2014-08-21T23:59:59.000Z

    We present a lattice QCD calculation of the up, down, strange and charm quark masses performed using the gauge configurations produced by the European Twisted Mass Collaboration with Nf = 2 + 1 + 1 dynamical quarks, which include in the sea, besides two light mass degenerate quarks, also the strange and charm quarks with masses close to their physical values. The simulations are based on a unitary setup for the two light quarks and on a mixed action approach for the strange and charm quarks. The analysis uses data at three values of the lattice spacing and pion masses in the range 210 - 450 MeV, allowing for accurate continuum limit and controlled chiral extrapolation. The quark mass renormalization is carried out non-perturbatively using the RI-MOM method. The results for the quark masses converted to the bar{MS} scheme are: mud(2 GeV) = 3.70(17) MeV, ms(2 GeV) = 99.6(4.3) MeV and mc(mc) = 1.348(46) GeV. We obtain also the quark mass ratios ms/mud = 26.66(32) and mc/ms = 11.62(16). By studying the mass splitting between the neutral and charged kaons and using available lattice results for the electromagnetic contributions, we evaluate mu/md = 0.470(56), leading to mu = 2.36(24) MeV and md = 5.03(26) MeV.

  4. Seismic Attribute Analysis Using Higher Order Statistics

    E-Print Network [OSTI]

    Greenidge, Janelle Candice

    2009-05-15T23:59:59.000Z

    Seismic data processing depends on mathematical and statistical tools such as convolution, crosscorrelation and stack that employ second-order statistics (SOS). Seismic signals are non-Gaussian and therefore contain information beyond SOS. One...

  5. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics Seminar Series STEFFEN LAURITZEN Department of Statistics University of Oxford Bayesian Networks for the Analysis of DNA Mixtures MONDAY, May 21, 2009, at 4

  6. Statistical Review of California's Organic Agriculture

    E-Print Network [OSTI]

    Ferrara, Katherine W.

    Statistical Review of California's Organic Agriculture 2005 ­ 2009 Karen Klonsky Kurt Richter Agricultural Issues Center University of California March 2011 #12;Statistical Review of California's Organic Agriculture 2005 ­ 2009 Karen Klonsky Extension Specialist Department of Agricultural and Resource Economics

  7. |Research Focus Statistical decision theory and evolution

    E-Print Network [OSTI]

    Maloney, Laurence T.

    |Research Focus Statistical decision theory and evolution Laurence T. Maloney Department recent articles by Geisler and Diehl use Bayesian statistical decision theory to model the co, an advantage that ultimately translates into `reproductive success'. The balance between predator and prey

  8. Kansas Statistical Abstract 2005 (40th Edition)

    E-Print Network [OSTI]

    Policy Research Institute

    2008-10-21T23:59:59.000Z

    The Kansas Statistical Abstract contains state, county, and city-level data for Kansas on population, vital statistics and health, housing, elections, education, business and manufacturing, exports, employment, income, finance, state and local...

  9. Kansas Statistical Abstract 2013 (48th Edition)

    E-Print Network [OSTI]

    Institute for Policy & Social Research

    2014-09-01T23:59:59.000Z

    The Kansas Statistical Abstract 2013, contains the latest available state, county, and city-level data for Kansas on population, vital statistics and health, housing, education, business and manufacturing, exports, employment, ...

  10. Kansas Statistical Abstract 2001 (36th Edition)

    E-Print Network [OSTI]

    2002-12-01T23:59:59.000Z

    The Kansas Statistical Abstract contains state, county, and city-level data for Kansas on population, vital statistics and health, housing, elections, education, business and manufacturing, exports, employment, income, ...

  11. Kansas Statistical Abstract 2004 (39th Edition)

    E-Print Network [OSTI]

    Policy Research Institute

    2006-01-31T23:59:59.000Z

    The Kansas Statistical Abstract contains state, county, and city-level data for Kansas on population, vital statistics and health, housing, elections, education, business and manufacturing, exports, employment, income, ...

  12. Kansas Statistical Abstract 2003 (38th Edition)

    E-Print Network [OSTI]

    Policy Research Institute

    2004-09-01T23:59:59.000Z

    The Kansas Statistical Abstract contains state, county, and city-level data for Kansas on population, vital statistics and health, housing, elections, education, business and manufacturing, exports, employment, income, ...

  13. Kansas Statistical Abstract 2012 (47th Edition)

    E-Print Network [OSTI]

    Institute for Policy & Social Research

    2014-05-27T23:59:59.000Z

    The Kansas Statistical Abstract 2012, contains the latest available state, county, and city-level data for Kansas on population, vital statistics and health, housing, education, business and manufacturing, exports, employment, ...

  14. Kansas Statistical Abstract 2002 (37th Edition)

    E-Print Network [OSTI]

    2003-09-01T23:59:59.000Z

    The Kansas Statistical Abstract contains state, county, and city-level data for Kansas on population, vital statistics and health, housing, elections, education, business and manufacturing, exports, employment, income, ...

  15. Stratigraphic statistical curvature analysis techniques

    SciTech Connect (OSTI)

    Bengtson, C.A.; Ziagos, J.P.

    1987-05-01T23:59:59.000Z

    SCAT applies statistical techniques to dipmeter data to identify patterns of bulk curvature, determine transverse and longitudinal structural directions, and reconstruct cross sections and contour maps. STRAT-SCAT applies the same concepts to geometric interpretation of multistoried unimodal, bimodal, or trough-type cross-bedding and also to seismic stratigraphy-scale stratigraphic structures. Structural dip, which comprises the bulk of dipmeter data, is related to beds that (statistically) were deposited with horizontal attitudes; stratigraphic dip is related to beds that were deposited with preferentially oriented nonhorizontal attitudes or to beds that assumed such attitudes because of differential compaction. Stratigraphic dip generates local zones of departure from structural dip on special SCAT plots. The RMS (root-mean-square) of apparent structural dip is greatest in the (structural) T-direction and least in the perpendicular L-direction; the RMS of stratigraphic dip (measured with respect to structural dip) is greatest in the stratigraphic T*-direction and least in the stratigraphic L*-direction. Multistoried, cross-bedding appears on T*-plots as local zones of either greater scatter or statistically significant departure of stratigraphic median dip from structural dip. In contrast, the L*-plot (except for trough-type cross-bedding) is sensitive to cross-bedding. Seismic stratigraphy-scale depositional sequences are identified on Mercator dip versus azimuth plots and polar tangent plots as secondary cylindrical-fold patterns imposed on global structural patterns. Progradational sequences generate local cycloid-type patterns on T*-plots, and compactional sequences generate local cycloid-type patterns on T*-plots, and compactional sequences generate local half-cusp patterns. Both features, however, show only structural dip on L*-plots.

  16. Statistics Department University of California, Berkeley

    E-Print Network [OSTI]

    California at Santa Cruz, University of

    John Rice Statistics Department University of California, Berkeley Joint work with Peter Bickel, no matter how rich the dictionary from which you adaptively compose a detection statistic, no matter how to be a [closet] Bayesian and choose directions a priori. Lehman & Romano. Testing Statistical Hypotheses. Chapt

  17. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    The University of Chicago Department of Statistics BAHADUR MEMORIAL LECTURES JAMES O. BERGER Department of Statistical Science Duke University Bayesian Adjustment for Multiplicity MONDAY, April 11, 2011 for multiplicity in non-Bayesian statistics. Not all assignments of prior probabilities adjust for multiplicity

  18. Statistics and Causal Inference PAUL W. HOLLAND*

    E-Print Network [OSTI]

    Fitelson, Branden

    Statistics and Causal Inference PAUL W. HOLLAND* Problems involving causal inference have dogged conclusions drawn from a carefully designed experiment are often valid. What can a statistical model say about in the most unexpected places, for example, "If the statistics cannot relate cause and effect, they can

  19. Rich Levine Department of Mathematics and Statistics

    E-Print Network [OSTI]

    Goldberg, Fred M.

    Rich Levine Department of Mathematics and Statistics San Diego State University Integrating Change in statistics instruction through the SDSU ITS Course Design Institute (CDI) and the CSU Promising Course Redesign program. The studies consider student success in an online offering of a core applied statistics

  20. Online Course Syllabus STATS 7: Basic Statistics

    E-Print Network [OSTI]

    Loudon, Catherine

    Online Course Syllabus Page 1 STATS 7: Basic Statistics Summer Session I 2011 Class Meeting at UC Irvine where she has been teaching statistics for many years. She is also involved in the development of educational material for statistics, from helping to conceive a TV program for distance

  1. Peter Brien Bureau of Justice Statistics

    E-Print Network [OSTI]

    Hemmers, Oliver

    Peter Brien Bureau of Justice Statistics Overview Federal law prohibits the transfer of a firearm been convicted of a domestic violence misdemeanor (18 USC § 922(g)). The Bureau of Justice Statistics provides as part of its Firearm Inquiry Statistics (FIST) project. Some of the highlights from the survey

  2. STATISTICS COLLOQUIUM MONDAY, MARCH 24, 2014

    E-Print Network [OSTI]

    Schrag, Daniel

    STATISTICS COLLOQUIUM MONDAY, MARCH 24, 2014 TALK: 4:15 PM -- SCIENCE CENTER RM. 705 RECEPTION: 3 Department of Statistics University of California, Berkeley ABSTRACT In a 2009 PNAS article, based on work at appropriate speeds. We discuss these results and argue that while they are hard to interpret statistically

  3. STATISTICS COLLOQUIUM MONDAY, SEPTEMBER 12, 2011

    E-Print Network [OSTI]

    Schrag, Daniel

    STATISTICS COLLOQUIUM MONDAY, SEPTEMBER 12, 2011 TALK: 4:00 PM -- SCIENCE CENTER RM. 309 RECEPTION Dasgupta Statistics Department Harvard University ABSTRACT A framework for causal inference from two experiments. The framework allows for statistical inference from a finite population, permits definition

  4. 40.530: Statistics Professor Chen Zehua

    E-Print Network [OSTI]

    Chen, Zehua

    40.530: Statistics Professor Chen Zehua Singapore University of Design and Technology Professor Chen Zehua 40.530: Statistics #12;Lecture 4: Population and sample, models, Sufficiency and completeness Population, sample and statistic Natural population: A natural population is usually a collection

  5. College of Arts and Sciences STA Statistics

    E-Print Network [OSTI]

    MacAdam, Keith

    College of Arts and Sciences STA Statistics KEY: # = new course * = course changed = course dropped University of Kentucky 2013-2014 Undergraduate Bulletin 1 STA 200 STATISTICS: A FORCE IN HUMAN JUDGMENT. (3) This course is concerned with the interaction of the science and art of statistics with our

  6. DEPARTMENT OF STATISTICS University of Wisconsin

    E-Print Network [OSTI]

    Sheridan, Jennifer

    REPORT NO. 1173 March 11, 2013 Statistical Model Building, Machine Learning, and the Ah-Ha Moment Grace assorted remarks. Fol- lowing is my contribution. 1 #12;Chapter 1 Statistical Model Building, Machine to young statisticians. We conclude with remarks on issues relating to statistical model building/machine

  7. Inga Maslova Department of Mathematics and Statistics

    E-Print Network [OSTI]

    Lansky, Joshua

    Inga Maslova Department of Mathematics and Statistics American University, Washington, D.C. 20016 EXPERIENCE Professor, American University, D.C. Sept 2009 ­ present "Basic Statistics" (Stat202) "Data, and L.Zhu (2010), Statistical significance testing for the association of the magnetometer records

  8. Spatial Autocorrelation and Statistical Tests: Some Solutions

    E-Print Network [OSTI]

    Fortin, Marie Josee

    .fortin@utoronto.ca). 188 © 2009 American Statistical Association and the International Biometric Society JournalSpatial Autocorrelation and Statistical Tests: Some Solutions Mark R. T. DALE and Marie problem in analysis, affecting the significance rates of statistical tests, making them too liberal when

  9. Tutorials on AstroStatistics and R

    E-Print Network [OSTI]

    Wolfe, Patrick J.

    Tutorials on AstroStatistics and R by Eric Feigelson Jan 29 and Jan 31, 2014 Phillips Auditorium in astronomical research [general interest lecture] 10:00am - 11:00am : Introduction to the R statistical software language [lecture & practicum] 11:00am - 2:30pm : break [EF available for informal statistical consulting

  10. Unsupervised Segmentation for Statistical Machine Translation

    E-Print Network [OSTI]

    Koehn, Philipp

    Unsupervised Segmentation for Statistical Machine Translation Siriwan Sereewattana TH E U N I V E R for statistical machine translation. The approach requires no language- nor domain-specific knowledge whatsoever in principle the statistical framework of machine translation can be ap- plied to any language pair

  11. EPSRC CASE Studentship Statistical Modelling of Fingerprints

    E-Print Network [OSTI]

    Oakley, Jeremy

    and mathematics together with experience or strong interest in statistical computing (including programming in R1 EPSRC CASE Studentship Statistical Modelling of Fingerprints SUMMARY This CASE studentship involves working with researchers in the Statistics & Interpretation Group of the Forensic Science Service

  12. General Database Statistics Using Entropy Maximization

    E-Print Network [OSTI]

    Suciu, Dan

    (z) Estimate: q(y) :- R(x, y), S(y, z) Fig. 1. An example of a Statistical Program and a query, q whoseGeneral Database Statistics Using Entropy Maximization Raghav Kaushik1 , Christopher R´e2 , and Dan engines. The key object of our study is a statistical program, which is a set of pairs (v, d), where v

  13. Nonstationary statistical theory for multipactor

    SciTech Connect (OSTI)

    Anza, S.; Vicente, C.; Gil, J. [Aurora Software and Testing S.L., Edificio de Desarrollo Empresarial 9B, Universidad Politecnica de Valencia, Camino de Vera s/n, 46022 Valencia (Spain); Boria, V. E. [Departamento de Comunicaciones-iTEAM, Universidad Politecnica de Valencia, Camino de Vera s/n, 46022 Valencia (Spain); Gimeno, B. [Departamento de Fisica Aplicada y Electromagnetismo-ICMUV, Universitat de Valencia, c/Dr. Moliner, 50, 46100 Valencia (Spain); Raboso, D. [Payloads Systems Division, European Space Agency, 2200-AG Noordwijk (Netherlands)

    2010-06-15T23:59:59.000Z

    This work presents a new and general approach to the real dynamics of the multipactor process: the nonstationary statistical multipactor theory. The nonstationary theory removes the stationarity assumption of the classical theory and, as a consequence, it is able to adequately model electron exponential growth as well as absorption processes, above and below the multipactor breakdown level. In addition, it considers both double-surface and single-surface interactions constituting a full framework for nonresonant polyphase multipactor analysis. This work formulates the new theory and validates it with numerical and experimental results with excellent agreement.

  14. On statistics of molecular chaos

    E-Print Network [OSTI]

    Yuriy Kuzovlev

    2009-11-03T23:59:59.000Z

    It is shown that the BBGKY equations for a particle interacting with ideal gas imply exact relations between probability distribution of path of the particle, its derivatives in respect to the gas density and irreducible many-particle correlations of gas atoms with the path. These relations visualize that the correlations of any order always significantly contribute to evolution of the path distribution, so that the exact statistical mechanics theory does not reduce to the classical kinetics even in the low-density (or Boltzmann-Grad) limit.

  15. Entanglement distillation using particle statistics

    E-Print Network [OSTI]

    H. L. Huang; L. H. Cheng; X. X. Yi

    2005-10-25T23:59:59.000Z

    We extend the idea of entanglement concentration for pure states(Phys. Rev. Lett. {\\bf 88}, 187903) to the case of mixed states. The scheme works only with particle statistics and local operations, without the need of any other interactions. We show that the maximally entangled state can be distilled out when the initial state is pure, otherwise the entanglement of the final state is less than one. The distillation efficiency is a product of the diagonal elements of the initial state, it takes the maximum 50%, the same as the case for pure states.

  16. Transportation Statistics Annual Report 1997

    SciTech Connect (OSTI)

    Fenn, M.

    1997-01-01T23:59:59.000Z

    This document is the fourth Transportation Statistics Annual Report (TSAR) prepared by the Bureau of Transportation Statistics (BTS) for the President and Congress. As in previous years, it reports on the state of U.S. transportation system at two levels. First, in Part I, it provides a statistical and interpretive survey of the system—its physical characteristics, its economic attributes, aspects of its use and performance, and the scale and severity of unintended consequences of transportation, such as fatalities and injuries, oil import dependency, and environment impacts. Part I also explores the state of transportation statistics, and new needs of the rapidly changing world of transportation. Second, Part II of the report, as in prior years, explores in detail the performance of the U.S. transportation system from the perspective of desired social outcomes or strategic goals. This year, the performance aspect of transportation chosen for thematic treatment is “Mobility and Access,” which complements past TSAR theme sections on “The Economic Performance of Transportation” (1995) and “Transportation and the Environment” (1996). Mobility and access are at the heart of the transportation system’s performance from the user’s perspective. In what ways and to what extent does the geographic freedom provided by transportation enhance personal fulfillment of the nation’s residents and contribute to economic advancement of people and businesses? This broad question underlies many of the topics examined in Part II: What is the current level of personal mobility in the United States, and how does it vary by sex, age, income level, urban or rural location, and over time? What factors explain variations? Has transportation helped improve people’s access to work, shopping, recreational facilities, and medical services, and in what ways and in what locations? How have barriers, such as age, disabilities, or lack of an automobile, affected these accessibility patterns? How are commodity flows and transportation services responding to global competition, deregulation, economic restructuring, and new information technologies? How do U.S. patterns of personal mobility and freight movement compare with other advanced industrialized countries, formerly centrally planned economies, and major newly industrializing countries? Finally, how is the rapid adoption of new information technologies influencing the patterns of transportation demand and the supply of new transportation services? Indeed, how are information technologies affecting the nature and organization of transportation services used by individuals and firms?

  17. Lectures on probability and statistics

    SciTech Connect (OSTI)

    Yost, G.P.

    1984-09-01T23:59:59.000Z

    These notes are based on a set of statistics lectures delivered at Imperial College to the first-year postgraduate students in High Energy Physics. They are designed for the professional experimental scientist. We begin with the fundamentals of probability theory, in which one makes statements about the set of possible outcomes of an experiment, based upon a complete a priori understanding of the experiment. For example, in a roll of a set of (fair) dice, one understands a priori that any given side of each die is equally likely to turn up. From that, we can calculate the probability of any specified outcome. We finish with the inverse problem, statistics. Here, one begins with a set of actual data (e.g., the outcomes of a number of rolls of the dice), and attempts to make inferences about the state of nature which gave those data (e.g., the likelihood of seeing any given side of any given die turn up). This is a much more difficult problem, of course, and one's solutions often turn out to be unsatisfactory in one respect or another.

  18. Statistical studies of supernova environments

    E-Print Network [OSTI]

    Anderson, Joseph P; Habergham, Stacey M; Galbany, Lluís; Kuncarayakti, Hanindyo

    2015-01-01T23:59:59.000Z

    Investigations of the environments of SNe allow statistical constraints to be made on progenitor properties. We review progress that has been made in this field. Pixel statistics using tracers of e.g. star formation within galaxies show differences in the explosion sites of, in particular SNe types II and Ibc (SNe II and SNe Ibc), suggesting differences in population ages. Of particular interest is that SNe Ic are significantly more associated with H-alpha emission than SNe Ib, implying shorter lifetimes for the former. In addition, such studies have shown that the interacting SNe IIn do not explode in regions containing the most massive stars, which suggests that at least a significant fraction of their progenitors arise from the lower end of the core-collapse SN mass range. Host HII region spectroscopy has been obtained for a significant number of core-collapse events, however definitive conclusions have to-date been elusive. Single stellar evolution models predict that the fraction of SNe Ibc to SNe II sho...

  19. Statistics Page 233Sonoma State University 2012-2013 Catalog DEPARTMENT OF MATHEMATICS AND STATISTICS

    E-Print Network [OSTI]

    Ravikumar, B.

    Statistics Page 233Sonoma State University 2012-2013 Catalog STATISTICS DEPARTMENT OF MATHEMATICS AND STATISTICS Darwin Hall 114 phone: (707) 664-2368 fax: (707) 664-3535 www.sonoma.edu/math DEPARTMENT CHAIR Sam Brannen STATISTICS PROGRAM ADVISORS Susan Herring Elaine McDonald-Newman Scott Nickleach ADMINISTRATIVE

  20. Branden Fitelson Remarks on the Philosophy of Statistics 0 SOME REMARKS ON THE PHILOSOPHY OF STATISTICS

    E-Print Network [OSTI]

    Fitelson, Branden

    Branden Fitelson Remarks on the Philosophy of Statistics 0 SOME REMARKS ON THE PHILOSOPHY OF STATISTICS BRANDEN FITELSON Department of Philosophy San Jos´e State University branden@fitelson.org http of Statistics 1 Overview of Presentation · What are the ends of statistical experiment, analysis

  1. Statistics Page 239Sonoma State University 2014-2015 Catalog DEPARTMENT OF MATHEMATICS AND STATISTICS

    E-Print Network [OSTI]

    Ravikumar, B.

    Statistics Page 239Sonoma State University 2014-2015 Catalog STATISTICS DEPARTMENT OF MATHEMATICS AND STATISTICS Darwin Hall 114 phone: (707) 664-2368 fax: (707) 664-3535 www.sonoma.edu/math DEPARTMENT CHAIR Brigitte Lahme STATISTICS PROGRAM ADVISORS Susan Herring Elaine Newman ADMINISTRATIVE COORDINATOR Marybeth

  2. Rosiglitazone attenuates NF-{kappa}B-dependent ICAM-1 and TNF-{alpha} production caused by homocysteine via inhibiting ERK{sub 1/2}/p38MAPK activation

    SciTech Connect (OSTI)

    Bai, Yong-Ping [Department of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha, Hunan 410078 (China); Liu, Yu-Hui [Department of Pharmacology, College of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi 330006 (China); Chen, Jia [Department of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha, Hunan 410078 (China); Song, Tao [Department of Pharmacology, School of Pharmaceutical Sciences, Central South University, Changsha, Hunan 410078 (China); You, Yu [Department of Digestive Medicine, Xiangya Second Hospital, Central South University, Changsha, Hunan 410078 (China); Tang, Zhen-Yan [Department of Urologic Surgery, Xiangya Hospital, Central South University, Changsha, Hunan 410078 (China); Li, Yuan-Jian [Department of Pharmacology, School of Pharmaceutical Sciences, Central South University, Changsha, Hunan 410078 (China); Zhang, Guo-Gang [Department of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha, Hunan 410078 (China)]. E-mail: xyzgg2006@sina.com

    2007-08-17T23:59:59.000Z

    Previous studies demonstrated an important interaction between nuclear factor-kappaB (NF-{kappa}B) activation and homocysteine (Hcy)-induced cytokines expression in endothelial cells and vascular smooth muscle cells. However, the underlying mechanism remains illusive. In this study, we investigated the effects of Hcy on NF-{kappa}B-mediated sICAM-1, TNF-{alpha} production and the possible involvement of ERK{sub 1/2}/p38MAPK pathway. The effects of rosiglitazone intervention were also examined. Our results show that Hcy increased the levels of sICAM-1 and TNF-{alpha} in cultured human umbilical vein endothelial cells (HUVECs) in a time- and concentration-dependent manner. This effect was significantly depressed by rosiglitazone and different inhibitors (PDTC, NF-{kappa}B inhibitor; PD98059, MEK inhibitor; SB203580, p38MAPK specific inhibitor; and staurosporine, PKC inhibitor). Next, we investigated the effect of Hcy on ERK{sub 1/2}/p38MAPK pathway and NF-{kappa}B activity in HUVECs. The results show that Hcy activated both ERK{sub 1/2}/p38MAPK pathway and NF-{kappa}B-DNA-binding activity. These effects were markedly inhibited by rosiglitazone as well as other inhibitors (SB203580, PD98059, and PDTC). Further, the pretreatment of staurosporine abrogated ERK{sub 1/2}/p38MAPK phosphorylation, suggesting that Hcy-induced ERK{sub 1/2}/p38MAPK activation is associated with PKC activity. Our results provide evidence that Hcy-induced NF-{kappa}B activation was mediated by activation of ERK{sub 1/2}/p38MAPK pathway involving PKC activity. Rosiglitazone reduces the NF-{kappa}B-mediated sICAM-1 and TNF-{alpha} production induced by Hcy via inhibition of ERK{sub 1/2}/p38MAPK pa0011thw.

  3. Workforce Statistics - NA SH | National Nuclear Security Administratio...

    National Nuclear Security Administration (NNSA)

    Us Our Operations Management and Budget Office of Civil Rights Workforce Statistics Workforce Statistics - NA SH Workforce Statistics - NA SH NA SH FY14 Year End...

  4. BS in STATISTICS: Applied Statistics and Analytics Emphasis (695234) MAP Sheet Department of Statistics

    E-Print Network [OSTI]

    Dahl, David B.

    ­2 1 1 1 1 1 2 1 1 1­2 1­2 1 3­4 Variable Hours 4.0 2.0 2.0 3­6.0 3.0 3.0 3.0 4.0 4.0 6.0 3.0 3.0 3­5.0 3­7.0 3.0 6.0 Variable 30.0 120.0 Classes Rel A 121/H & 122/H Rel A 211/H or 212/H Rel C 324/H Statistical Computing 2 4.0 4.0 3.0 3.0 3.0 3.0 1.0 1.0 2.0 3.0 3.0 1.0 3.0 3.0 3.0 3.0 Complete 18 credit

  5. Mining, Using and Maintaining Source Statistics for Adaptive Data Integration

    E-Print Network [OSTI]

    Kambhampati, Subbarao

    -Objective Optimization, Statistics Mining, Incremental Maintenance 1. INTRODUCTION The availability of structuredMining, Using and Maintaining Source Statistics for Adaptive Data Integration Jianchun Fan a framework for effectively mining multiple types of statistics including source coverage statistics, inter

  6. Anti-neuroinflammatory efficacy of the aldose reductase inhibitor FMHM via phospholipase C/protein kinase C-dependent NF-?B and MAPK pathways

    SciTech Connect (OSTI)

    Zeng, Ke-Wu [State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191 (China); Li, Jun [Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029 (China); Dong, Xin; Wang, Ying-Hong; Ma, Zhi-Zhong; Jiang, Yong; Jin, Hong-Wei [State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191 (China); Tu, Peng-Fei, E-mail: pengfeitu@vip.163.com [State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191 (China); Modern Research Center for Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029 (China)

    2013-11-15T23:59:59.000Z

    Aldose reductase (AR) has a key role in several inflammatory diseases: diabetes, cancer and cardiovascular diseases. Therefore, AR inhibition seems to be a useful strategy for anti-inflammation therapy. In the central nervous system (CNS), microglial over-activation is considered to be a central event in neuroinflammation. However, the effects of AR inhibition in CNS inflammation and its underlying mechanism of action remain unknown. In the present study, we found that FMHM (a naturally derived AR inhibitor from the roots of Polygala tricornis Gagnep.) showed potent anti-neuroinflammatory effects in vivo and in vitro by inhibiting microglial activation and expression of inflammatory mediators. Mechanistic studies showed that FMHM suppressed the activity of AR-dependent phospholipase C/protein kinase C signaling, which further resulted in downstream inactivation of the I?B kinase/I?B/nuclear factor-kappa B (NF-?B) inflammatory pathway. Therefore, AR inhibition-dependent NF-?B inactivation negatively regulated the transcription and expression of various inflammatory genes. AR inhibition by FMHM exerted neuroprotective effects in lipopolysaccharide-induced neuron–microglia co-cultures. These findings suggested that AR is a potential target for neuroinflammation inhibition and that FMHM could be an effective agent for treating or preventing neuroinflammatory diseases. - Highlights: • FMHM is a natural-derived aldose reductase (AR) inhibitor. • FMHM inhibits various neuroinflammatory mediator productions in vitro and in vivo. • FMHM inhibits neuroinflammation via aldose reductase/PLC/PKC-dependent NF-?B pathway. • FMHM inhibits neuroinflammation via aldose reductase/PLC/PKC-dependent MAPK pathway. • FMHM protects neurons against inflammatory injury in microglia-neuron co-cultures.

  7. Impaired NFAT and NF?B activation are involved in suppression of CD40 ligand expression by ?{sup 9}-tetrahydrocannabinol in human CD4{sup +} T cells

    SciTech Connect (OSTI)

    Ngaotepprutaram, Thitirat [Department of Pharmacology and Toxicology, Michigan State University (United States); Center for Integrative Toxicology, Michigan State University (United States); Kaplan, Barbara L.F. [Department of Pharmacology and Toxicology, Michigan State University (United States); Center for Integrative Toxicology, Michigan State University (United States); Neuroscience Program, Michigan State University (United States); Kaminski, Norbert E., E-mail: kamins11@msu.edu [Department of Pharmacology and Toxicology, Michigan State University (United States); Center for Integrative Toxicology, Michigan State University (United States)

    2013-11-15T23:59:59.000Z

    We have previously reported that ?{sup 9}-tetrahydrocannabinol (?{sup 9}-THC), the main psychoactive cannabinoid in marijuana, suppresses CD40 ligand (CD40L) expression by activated mouse CD4{sup +} T cells. CD40L is involved in pathogenesis of many autoimmune and inflammatory diseases. In the present study, we investigated the molecular mechanism of ?{sup 9}-THC-mediated suppression of CD40L expression using peripheral blood human T cells. Pretreatment with ?{sup 9}-THC attenuated CD40L expression in human CD4{sup +} T cells activated by anti-CD3/CD28 at both the protein and mRNA level, as determined by flow cytometry and quantitative real-time PCR, respectively. Electrophoretic mobility shift assays revealed that ?{sup 9}-THC suppressed the DNA-binding activity of both NFAT and NF?B to their respective response elements within the CD40L promoter. An assessment of the effect of ?{sup 9}-THC on proximal T cell-receptor (TCR) signaling induced by anti-CD3/CD28 showed significant impairment in the rise of intracellular calcium, but no significant effect on the phosphorylation of ZAP70, PLC?1/2, Akt, and GSK3?. Collectively, these findings identify perturbation of the calcium-NFAT and NF?B signaling cascade as a key mechanistic event by which ?{sup 9}-THC suppresses human T cell function. - Highlights: • ?{sup 9}-THC attenuated CD40L expression in activated human CD4+ T cells. • ?{sup 9}-THC suppressed DNA-binding activity of NFAT and NF?B. • ?{sup 9}-THC impaired elevation of intracellular Ca2+. • ?{sup 9}-THC did not affect phosphorylation of ZAP70, PLC?1/2, Akt, and GSK3?.

  8. Statistical assessment of Monte Carlo distributional tallies

    SciTech Connect (OSTI)

    Kiedrowski, Brian C [Los Alamos National Laboratory; Solomon, Clell J [Los Alamos National Laboratory

    2010-12-09T23:59:59.000Z

    Four tests are developed to assess the statistical reliability of distributional or mesh tallies. To this end, the relative variance density function is developed and its moments are studied using simplified, non-transport models. The statistical tests are performed upon the results of MCNP calculations of three different transport test problems and appear to show that the tests are appropriate indicators of global statistical quality.

  9. Quantum Statistical Mechanics. III. Equilibrium Probability

    E-Print Network [OSTI]

    Phil Attard

    2014-04-10T23:59:59.000Z

    Given are a first principles derivation and formulation of the probabilistic concepts that underly equilibrium quantum statistical mechanics. The transition to non-equilibrium probability is traversed briefly.

  10. 18.441 Statistical Inference, Spring 2002

    E-Print Network [OSTI]

    Hardy, Michael

    Reviews probability and introduces statistical inference. Point and interval estimation. The maximum likelihood method. Hypothesis testing. Likelihood-ratio tests and Bayesian methods. Nonparametric methods. Analysis of ...

  11. Essays on microeconomics and statistical decision making

    E-Print Network [OSTI]

    Nieto Barthaburu, Augusto

    2006-01-01T23:59:59.000Z

    An Introduction to Econometric Theory. Princeton Universityand S. Low (1989): An Econometric Analysis of the Bankextensive statistical and econometric literature concerned

  12. Statistical methods for nuclear material management

    SciTech Connect (OSTI)

    Bowen W.M.; Bennett, C.A. (eds.) [eds.

    1988-12-01T23:59:59.000Z

    This book is intended as a reference manual of statistical methodology for nuclear material management practitioners. It describes statistical methods currently or potentially important in nuclear material management, explains the choice of methods for specific applications, and provides examples of practical applications to nuclear material management problems. Together with the accompanying training manual, which contains fully worked out problems keyed to each chapter, this book can also be used as a textbook for courses in statistical methods for nuclear material management. It should provide increased understanding and guidance to help improve the application of statistical methods to nuclear material management problems.

  13. The NSVZ beta-function and the Schwinger-Dyson equations for N=1 SQED with N_f flavors, regularized by higher derivatives

    E-Print Network [OSTI]

    K. V. Stepanyantz

    2014-06-08T23:59:59.000Z

    The effective diagram technique based on the Schwinger-Dyson equations is constructed for N=1 SQED with N_f flavors, regularized by higher derivatives. Using these effective diagrams, it is possible to derive the exact NSVZ relation between the beta-function and the anomalous dimension of the matter superfields exactly in all loops, if the renormalization group functions are defined in terms of the bare coupling constant. In particular, we verify that all integrals which give the beta-function defined in terms of the bare coupling constant are integrals of double total derivatives and prove some identities relating Green functions.

  14. OSU-A9 inhibits angiogenesis in human umbilical vein endothelial cells via disrupting Akt–NF-?B and MAPK signaling pathways

    SciTech Connect (OSTI)

    Omar, Hany A. [Division of Medicinal Chemistry, College of Pharmacy, The Ohio State University, Columbus, OH 43210 (United States); Department of Pharmacology, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514 (Egypt); Arafa, El-Shaimaa A. [Department of Pharmacology, Faculty of Pharmacy, Beni-Suef University, Beni-Suef 62514 (Egypt); Salama, Samir A. [Department of Biochemistry, Faculty of Pharmacy, Al-Azhar University, Cairo 11511 (Egypt); Arab, Hany H. [Department of Biochemistry, Faculty of Pharmacy, Cairo University, Cairo 11562 (Egypt); Wu, Chieh-Hsi, E-mail: chhswu@mail.cmu.edu.tw [School of Pharmacy, China Medical University, Taichung 40402, Taiwan (China); Weng, Jing-Ru, E-mail: columnster@gmail.com [Department of Biological Science and Technology, China Medical University, Taichung 40402, Taiwan (China)

    2013-11-01T23:59:59.000Z

    Since the introduction of angiogenesis as a useful target for cancer therapy, few agents have been approved for clinical use due to the rapid development of resistance. This problem can be minimized by simultaneous targeting of multiple angiogenesis signaling pathways, a potential strategy in cancer management known as polypharmacology. The current study aimed at exploring the anti-angiogenic activity of OSU-A9, an indole-3-carbinol-derived pleotropic agent that targets mainly Akt–nuclear factor-kappa B (NF-?B) signaling which regulates many key players of angiogenesis such as vascular endothelial growth factor (VEGF) and matrix metalloproteinases (MMPs). Human umbilical vein endothelial cells (HUVECs) were used to study the in vitro anti-angiogenic effect of OSU-A9 on several key steps of angiogenesis. Results showed that OSU-A9 effectively inhibited cell proliferation and induced apoptosis and cell cycle arrest in HUVECs. Besides, OSU-A9 inhibited angiogenesis as evidenced by abrogation of migration/invasion and Matrigel tube formation in HUVECs and attenuation of the in vivo neovascularization in the chicken chorioallantoic membrane assay. Mechanistically, Western blot, RT-PCR and ELISA analyses showed the ability of OSU-A9 to inhibit MMP-2 production and VEGF expression induced by hypoxia or phorbol-12-myristyl-13-acetate. Furthermore, dual inhibition of Akt–NF-?B and mitogen-activated protein kinase (MAPK) signaling, the key regulators of angiogenesis, was observed. Together, the current study highlights evidences for the promising anti-angiogenic activity of OSU-A9, at least in part through the inhibition of Akt–NF-?B and MAPK signaling and their consequent inhibition of VEGF and MMP-2. These findings support OSU-A9's clinical promise as a component of anticancer therapy. - Highlights: • The antiangiogenic activity of OSU-A9 in HUVECs was explored. • OSU-A9 inhibited HUVECs proliferation, migration, invasion and tube formation. • OSU-A9 targeted signaling pathways mediated by Akt-NF-kB, VEGF, and MMP-2. • The anti-angiogenic activity of OSU-A9 supports its clinical promise.

  15. Statistical Mechanics and Quantum Cosmology

    E-Print Network [OSTI]

    B. L. Hu

    1995-11-29T23:59:59.000Z

    Statistical mechanical concepts and processes such as decoherence, correlation, and dissipation can prove to be of basic importance to understanding some fundamental issues of quantum cosmology and theoretical physics such as the choice of initial states, quantum to classical transition and the emergence of time. Here we summarize our effort in 1) constructing a unified theoretical framework using techniques in interacting quantum field theory such as influence functional and coarse-grained effective action to discuss the interplay of noise, fluctuation, dissipation and decoherence; and 2) illustrating how these concepts when applied to quantum cosmology can alter the conventional views on some basic issues. Two questions we address are 1) the validity of minisuperspace truncation, which is usually assumed without proof in most discussions, and 2) the relevance of specific initial conditions, which is the prevailing view of the past decade. We also mention how some current ideas in chaotic dynamics, dissipative collective dynamics and complexity can alter our view of the quantum nature of the universe.

  16. Mathematics & Statistics Coop Program Students from the Mathematics & Statistics Coop Program have conducted work terms in the fields of actuarial

    E-Print Network [OSTI]

    Hitchcock, Adam P.

    Mathematics & Statistics Coop Program Students from the Mathematics & Statistics Coop Program have design and data analysis, medical imaging, mathematical finance and statistical modeling. They have of Mathematics & Statistics Coop Work Terms Duties: Performed data mapping and analysis activities Derived

  17. American Statistical Association Announces 2011 Award Recipients Awards ceremony to be held at Joint Statistical Meetings in Miami Beach, FL

    E-Print Network [OSTI]

    Washington at Seattle, University of

    American Statistical Association Announces 2011 Award Recipients Awards ceremony to be held at Joint Statistical Meetings in Miami Beach, FL MIAMI BEACH, FL (PRWEB) AUGUST 1, 2011 ­ The American Statistical Association (ASA), the nation's preeminent professional statistical society, today announced

  18. BS in ACTUARIAL SCIENCE (695224) MAP Sheet Department of Statistics

    E-Print Network [OSTI]

    Olsen Jr., Dan R.

    BS in ACTUARIAL SCIENCE (695224) MAP Sheet Department of Statistics For students entering of Statistics Stat 151 Intro to Bayesian Statistics Stat 201 Statistics for Engineers & Scientists Stat 301 Statistics & Probability for Sec Ed Note: Students who have passed the AP statistics exam or an introductory

  19. November 2011 MSc and Diploma in Applied Statistics 2011

    E-Print Network [OSTI]

    Goldschmidt, Christina

    ;2 Statistical Methods 28 17 3.0 3 Statistical Theory 27 12 5.0 4 Statistical Theory 27 8 5.5 5 R Programming 28November 2011 MSc and Diploma in Applied Statistics 2011: Examiners' Report Part I A STATISTICS (1) Numbers and percentages in each category MSc in Applied Statistics Category Number Percentage 2010

  20. 8.334 Statistical Mechanics II: Statistical Mechanics of Fields, Spring 2004

    E-Print Network [OSTI]

    Kardar, Mehran

    A two-semester course on statistical mechanics. Basic principles are examined in 8.333: the laws of thermodynamics and the concepts of temperature, work, heat, and entropy. Postulates of classical statistical mechanics, ...

  1. Vortex methods and vortex statistics

    SciTech Connect (OSTI)

    Chorin, A.J.

    1993-05-01T23:59:59.000Z

    Vortex methods originated from the observation that in incompressible, inviscid, isentropic flow vorticity (or, more accurately, circulation) is a conserved quantity, as can be readily deduced from the absence of tangential stresses. Thus if the vorticity is known at time t = 0, one can deduce the flow at a later time by simply following it around. In this narrow context, a vortex method is a numerical method that makes use of this observation. Even more generally, the analysis of vortex methods leads, to problems that are closely related to problems in quantum physics and field theory, as well as in harmonic analysis. A broad enough definition of vortex methods ends up by encompassing much of science. Even the purely computational aspects of vortex methods encompass a range of ideas for which vorticity may not be the best unifying theme. The author restricts himself in these lectures to a special class of numerical vortex methods, those that are based on a Lagrangian transport of vorticity in hydrodynamics by smoothed particles (``blobs``) and those whose understanding contributes to the understanding of blob methods. Vortex methods for inviscid flow lead to systems of ordinary differential equations that can be readily clothed in Hamiltonian form, both in three and two space dimensions, and they can preserve exactly a number of invariants of the Euler equations, including topological invariants. Their viscous versions resemble Langevin equations. As a result, they provide a very useful cartoon of statistical hydrodynamics, i.e., of turbulence, one that can to some extent be analyzed analytically and more importantly, explored numerically, with important implications also for superfluids, superconductors, and even polymers. In the authors view, vortex ``blob`` methods provide the most promising path to the understanding of these phenomena.

  2. QUEEN'S UNIVERSITY STAT 367: Engineering Statistics

    E-Print Network [OSTI]

    Offin, Dan

    QUEEN'S UNIVERSITY STAT 367: Engineering Statistics Winter, 2010 Instructor: Charles Molson, Jeffery 206, cmolson@mast.queensu.ca, 613-533-2416 Text: Engineering Statistics 4th Edition, by D% or 10%, 10%, 80% evaluation schemes. You can logon to the course WebCT site at www

  3. Multimedia Statistical Labs & Toolkit (TILE) Deborah Nolan

    E-Print Network [OSTI]

    Nolan, Deborah

    Multimedia Statistical Labs & Toolkit (TILE) Deborah Nolan University of California, Department@research.bell-labs.com 1. Introduction The potential for multimedia to enhance the statistics curriculum is clear, but how to develop instructional materials that take advantage of the riches that multimedia has to offer

  4. Wavelet Methods in Statistics with R

    E-Print Network [OSTI]

    Nason, Guy

    Use R! G.P.Nason Use R! Wavelet Methods in Statistics with R WaveletMethodsinStatisticswithR Wavelet methods have recently undergone a rapid period of development with important impli- cations an introduction to wavelets and their uses in statistics; (ii) acting as a quick and broad reference to many

  5. Scientific Data Analysis via Statistical Learning

    E-Print Network [OSTI]

    Geddes, Cameron Guy Robinson

    observations and simulations. Statistical machine learning algorithms have enormous potential to provide data, and the analysis of hurricanes and tropical storms in climate simulations. #12;Supervised Learning for SupernovaScientific Data Analysis via Statistical Learning Raquel Romano romano at hpcrd dot lbl dot gov

  6. Empirical Comparison of Statistical Pavement Performance Models

    E-Print Network [OSTI]

    sections from the American Association of State Highway Officials AASHO Road Test Highway Research BoardEmpirical Comparison of Statistical Pavement Performance Models Chih-Yuan Chu1 and Pablo L. Durango-Cohen2 Abstract: We conduct an empirical comparison of nine representative statistical pavement

  7. Statistical Model Computation with UDFs Carlos Ordonez

    E-Print Network [OSTI]

    Ordonez, Carlos

    , USA Abstract--Statistical models are generally computed outside a DBMS due to their mathematical complexity. We introduce techniques to efficiently compute fundamental statistical models inside a DBMS of primitive scalar UDFs to score data sets. Experiments compare UDFs and SQL queries (running inside the DBMS

  8. NONEQUILIBRIUM QUANTUM STATISTICAL MECHANICS AND THERMODYNAMICS #

    E-Print Network [OSTI]

    NONEQUILIBRIUM QUANTUM STATISTICAL MECHANICS AND THERMODYNAMICS # Walid K. Abou Salem + Institut f recent progress in deriving the fundamental laws of thermodynamics (0 th , 1 st and 2 nd ­law) from nonequilibrium quantum statistical mechanics. Basic thermodynamic notions are clarified and di#erent reversible

  9. On statistical mechanics in noncommutative spaces

    E-Print Network [OSTI]

    S. A. Alavi

    2007-09-26T23:59:59.000Z

    We study the formulation of quantum statistical mechanics in noncommutative spaces. We construct microcanonical and canonical ensemble theory in noncommutative spaces. We consider for illustration some basic and important examples in the framework of noncommutative statistical mechanics : (i). An electron in a magnetic field. (ii). A free particle in a box. (iii). A linear harmonic oscillator.

  10. Factored Language Models for Statistical Machine Translation

    E-Print Network [OSTI]

    Koehn, Philipp

    Factored Language Models for Statistical Machine Translation Amittai E. Axelrod TH E U N I V E R . . . . . . . . . . . . . . . . . . . . . 10 2.4.3 Log-Linear, Phrase-Based Translation Models . . . . . . . . . 11 3 Statistical Language S ITY OF E D I N B U R G H Master of Science by Research Institute for Communicating and Collaborative

  11. Introduction to Statistical Linear Models Spring 2005

    E-Print Network [OSTI]

    of multivariate data and in the language of matrices and vectors. Broad introduction to MATLAB/Octave, R (SSyllabus Introduction to Statistical Linear Models 960:577:01 Spring 2005 Instructor: Farid Statistical Analysis" Fifth edition, Prentice Hall, 2002. Other sources may be required and will be posted

  12. : ( Statistical computing) : (Pi-Wen Tsai)

    E-Print Network [OSTI]

    Tsai, Pi-Wen

    computing "methods", with an emphasis on using the R language (http://www.r-project.org/) via an examples-Hastings algorithm, Gibbs sampler. 9. EM algorithm , (a) Rizzo, M. L. (2007), Statistical computing with R : ( Statistical computing) : (Pi-Wen Tsai) E-mail : pwtsai@math.ntnu.edu.tw or pwtsai

  13. Improving Statistical Machine Translation with Monolingual Collocation

    E-Print Network [OSTI]

    Wang, Haifeng

    monolingual collocations to improve Statistical Ma- chine Translation (SMT). We make use of the collocation for various kinds of SMT sys- tems and improving phrase table for phrase-based SMT. The experimental re- sults on a phrase-based SMT system and 1.76 BLEU score on a parsing-based SMT system. 1 Introduction Statistical

  14. Mathematics and Statistics College of Engineering

    E-Print Network [OSTI]

    Hickman, Mark

    and Statistics is located in the Erskine building. Reception is on Level 4 on the north side. The department has of computers in a wide range of academic areas has led to an increasing demand for statistical and mathematical new tools and techniques to deal with problems in areas from business management to biology, as well

  15. Degenerate U-and V -statistics under ergodicity: Asymptotics, bootstrap and applications in statistics

    E-Print Network [OSTI]

    Degenerate U- and V -statistics under ergodicity: Asymptotics, bootstrap and applications in statistics Anne Leucht Universit¨at Hamburg Fachbereich Mathematik, SPST Bundesstra�e 55 D-20146 Hamburg.neumann@uni-jena.de Abstract We derive the asymptotic distributions of degenerate U- and V -statistics of stationary

  16. Principles of Statistical Inference Department of Statistics, University of Toronto, Canada

    E-Print Network [OSTI]

    Reid, Nancy

    and D. R. Cox Nuffield College, Oxford, UK Abstract Statistical theory aims to provide a foundationPrinciples of Statistical Inference N. Reid Department of Statistics, University of Toronto, Canada, and a common language for summarizing results; ideally the foundations and common language ensure

  17. NF_Eder_2013

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Saleshttp://www.fnal.gov/directorate/nalcal/nalcal02_07_05_files/nalcal.gif Directorate1, Issue 23 NETL NEVIS- 97NEWS RELEASE For3

  18. JANEX-1, a JAK3 inhibitor, protects pancreatic islets from cytokine toxicity through downregulation of NF-{kappa}B activation and the JAK/STAT pathway

    SciTech Connect (OSTI)

    Lv, Na; Kim, Eun-Kyung; Song, Mi-Young [Department of Biochemistry, Medical School and Diabetes Research Center, Chonbuk National University, Jeonju, Jeonbuk 561-756 (Korea, Republic of)] [Department of Biochemistry, Medical School and Diabetes Research Center, Chonbuk National University, Jeonju, Jeonbuk 561-756 (Korea, Republic of); Choi, Ha-Na; Moon, Woo Sung [Department of Pathology, Medical School and Diabetes Research Center, Chonbuk National University, Jeonju, Jeonbuk 561-756 (Korea, Republic of)] [Department of Pathology, Medical School and Diabetes Research Center, Chonbuk National University, Jeonju, Jeonbuk 561-756 (Korea, Republic of); Park, Sung-Joo [Department of Herbology, School of Oriental Medicine, Wonkwang University, Iksan, Jeonbuk 570-749 (Korea, Republic of)] [Department of Herbology, School of Oriental Medicine, Wonkwang University, Iksan, Jeonbuk 570-749 (Korea, Republic of); Park, Jin-Woo [Department of Biochemistry, Medical School and Diabetes Research Center, Chonbuk National University, Jeonju, Jeonbuk 561-756 (Korea, Republic of)] [Department of Biochemistry, Medical School and Diabetes Research Center, Chonbuk National University, Jeonju, Jeonbuk 561-756 (Korea, Republic of); Kwon, Kang-Beom, E-mail: desson@wonkwang.ac.kr [Department of Physiology, School of Oriental Medicine, Wonkwang University, Iksan, Jeonbuk 570-749 (Korea, Republic of)] [Department of Physiology, School of Oriental Medicine, Wonkwang University, Iksan, Jeonbuk 570-749 (Korea, Republic of); Park, Byung-Hyun, E-mail: bhpark@chonbuk.ac.kr [Department of Biochemistry, Medical School and Diabetes Research Center, Chonbuk National University, Jeonju, Jeonbuk 561-756 (Korea, Republic of)] [Department of Biochemistry, Medical School and Diabetes Research Center, Chonbuk National University, Jeonju, Jeonbuk 561-756 (Korea, Republic of)

    2009-07-15T23:59:59.000Z

    JANEX-1/WHI-P131, a selective Janus kinase 3 (JAK3) inhibitor, has been shown to delay the onset of diabetes in the NOD mouse model. However, the molecular mechanism by which JANEX-1 protects pancreatic {beta}-cells is unknown. In the current study, we investigated the role of JANEX-1 on interleukin (IL)-1{beta} and interferon (IFN)-{gamma}-induced {beta}-cell damage using isolated islets. JANEX-1-pretreated islets showed resistance to cytokine toxicity, namely suppressed nitric oxide (NO) production, reduced inducible form of NO synthase (iNOS) expression, and decreased islet destruction. The molecular mechanism by which JANEX-1 inhibits iNOS expression was mediated through suppression of the nuclear factor {kappa}B (NF-{kappa}B) and JAK/signal transducer and activator of transcription (STAT) pathways. Islets treated with the cytokines downregulated the protein levels of suppressor of cytokine signaling (SOCS)-1 and SOCS-3, but pretreatment with JANEX-1 attenuated these decreases. Additionally, islets from JAK3{sup -/-} mice were more resistant to cytokine toxicity than islets from control mice. These results demonstrate that JANEX-1 protects {beta}-cells from cytokine toxicity through suppression of the NF-{kappa}B and JAK/STAT pathways and upregulation of SOCS proteins, suggesting that JANEX-1 may be used to preserve functional {beta}-cell mass.

  19. Early induction of cytokines/cytokine receptors and Cox2, and activation of NF-?B in 4-nitroquinoline 1-oxide-induced murine oral cancer model

    SciTech Connect (OSTI)

    Liu, Yu-Ching [Department of Medical Research, China Medical University Hospital, Taichung 404, Taiwan (China) [Department of Medical Research, China Medical University Hospital, Taichung 404, Taiwan (China); Department of Veterinary Medicine, National Chung Hsing University, Taichung 402, Taiwan (China); Ho, Heng-Chien; Lee, Miau-Rong [Department of Biochemistry, China Medical University, Taichung 404, Taiwan (China)] [Department of Biochemistry, China Medical University, Taichung 404, Taiwan (China); Lai, Kuang-Chi [Department of Surgery, China Medical University Beigang Hospital, Yunlin 651, Taiwan (China) [Department of Surgery, China Medical University Beigang Hospital, Yunlin 651, Taiwan (China); School of Medicine, China Medical University, Taichung 404, Taiwan (China); Yeh, Chung-Min; Lin, Yueh-Min [Department of Pathology, Changhua Christian Hospital, Changhua 500, Taiwan (China)] [Department of Pathology, Changhua Christian Hospital, Changhua 500, Taiwan (China); Ho, Tin-Yun [School of Chinese Medicine, China Medical University, Taichung 404, Taiwan (China)] [School of Chinese Medicine, China Medical University, Taichung 404, Taiwan (China); Hsiang, Chien-Yun, E-mail: cyhsiang@mail.cmu.edu.tw [Department of Microbiology, China Medical University, Taichung 404, Taiwan (China)] [Department of Microbiology, China Medical University, Taichung 404, Taiwan (China); Chung, Jing-Gung, E-mail: jgchung@mail.cmu.edu.tw [Department of Biological Science and Technology, China Medical University, Taichung 404, Taiwan (China) [Department of Biological Science and Technology, China Medical University, Taichung 404, Taiwan (China); Department of Biotechnology, Asia University, Taichung 413, Taiwan (China)

    2012-07-15T23:59:59.000Z

    The purpose of this study was to identify the genes induced early in murine oral carcinogenesis. Murine tongue tumors induced by the carcinogen, 4-nitroquinoline 1-oxide (4-NQO), and paired non-tumor tissues were subjected to microarray analysis. Hierarchical clustering of upregulated genes in the tumor tissues revealed an association of induced genes with inflammation. Cytokines/cytokine receptors induced early were subsequently identified, clearly indicating their involvement in oral carcinogenesis. Hierarchical clustering also showed that cytokine-mediated inflammation was possibly linked with Mapk6. Cox2 exhibited the greatest extent (9–18 fold) of induction in the microarray data, and its early induction was observed in a 2 h painting experiment by RT-PCR. MetaCore analysis showed that overexpressed Cox2 may interact with p53 and transcriptionally inhibit expression of several downstream genes. A painting experiment in transgenic mice also demonstrated that NF-?B activates early independently of Cox2 induction. MetaCore analysis revealed the most striking metabolic alterations in tumor tissues, especially in lipid metabolism resulting from the reduction of Ppar? and Rxrg. Reduced expression of Mapk12 was noted, and MetaCore analysis established its relationship with decreased efficiency of Ppar? phosphorylation. In conclusion, in addition to cytokines/cytokine receptors, the early induction of Cox2 and NF-?B activation is involved in murine oral carcinogenesis.

  20. High-loop perturbative renormalization constants for Lattice QCD (III): three-loop quark currents for Iwasaki gauge action and n_f=4 Wilson fermions

    E-Print Network [OSTI]

    M. Brambilla; F. Di Renzo; M. Hasegawa

    2014-06-23T23:59:59.000Z

    This is the third of a series of papers on three-loop computation of renormalization constants for Lattice QCD. Our main point of interest are results for the regularization defined by Iwasaki gauge action and n_f=4 Wilson fermions. Our results for quark bilinears renormalized according to the RI'-MOM scheme can be compared to non-perturbative results. The latter are available for Twisted Mass QCD: being defined in the chiral limit, renormalization constants must be the same. We also address more general problems. In particular, we discuss a few methodological issues connected to summing the perturbative series such as the effectiveness of Boosted Perturbation Theory and the disentanglement of irrelevant and finite volume contributions. Discussing these issues we consider ont only the new results of this paper, but also those for the regularization defined by tree-level Symanzik improved gauge action and n_f=2 Wilson fermions, which we presented in a recent paper of ours. We finally comment to which extent the techniques we put at work in the NSPT context can provide a fresher look into the lattice version of the RI'-MOM scheme.

  1. Topology for statistical modeling of petascale data.

    SciTech Connect (OSTI)

    Pascucci, Valerio (University of Utah, Salt Lake City, UT); Mascarenhas, Ajith Arthur; Rusek, Korben (Texas A& M University, College Station, TX); Bennett, Janine Camille; Levine, Joshua (University of Utah, Salt Lake City, UT); Pebay, Philippe Pierre; Gyulassy, Attila (University of Utah, Salt Lake City, UT); Thompson, David C.; Rojas, Joseph Maurice (Texas A& M University, College Station, TX)

    2011-07-01T23:59:59.000Z

    This document presents current technical progress and dissemination of results for the Mathematics for Analysis of Petascale Data (MAPD) project titled 'Topology for Statistical Modeling of Petascale Data', funded by the Office of Science Advanced Scientific Computing Research (ASCR) Applied Math program. Many commonly used algorithms for mathematical analysis do not scale well enough to accommodate the size or complexity of petascale data produced by computational simulations. The primary goal of this project is thus to develop new mathematical tools that address both the petascale size and uncertain nature of current data. At a high level, our approach is based on the complementary techniques of combinatorial topology and statistical modeling. In particular, we use combinatorial topology to filter out spurious data that would otherwise skew statistical modeling techniques, and we employ advanced algorithms from algebraic statistics to efficiently find globally optimal fits to statistical models. This document summarizes the technical advances we have made to date that were made possible in whole or in part by MAPD funding. These technical contributions can be divided loosely into three categories: (1) advances in the field of combinatorial topology, (2) advances in statistical modeling, and (3) new integrated topological and statistical methods.

  2. Spin - or, actually: Spin and Quantum Statistics

    E-Print Network [OSTI]

    Juerg Froehlich

    2008-02-29T23:59:59.000Z

    The history of the discovery of electron spin and the Pauli principle and the mathematics of spin and quantum statistics are reviewed. Pauli's theory of the spinning electron and some of its many applications in mathematics and physics are considered in more detail. The role of the fact that the tree-level gyromagnetic factor of the electron has the value g = 2 in an analysis of stability (and instability) of matter in arbitrary external magnetic fields is highlighted. Radiative corrections and precision measurements of g are reviewed. The general connection between spin and statistics, the CPT theorem and the theory of braid statistics are described.

  3. Scalable k-means statistics with Titan.

    SciTech Connect (OSTI)

    Thompson, David C.; Bennett, Janine C.; Pebay, Philippe Pierre

    2009-11-01T23:59:59.000Z

    This report summarizes existing statistical engines in VTK/Titan and presents both the serial and parallel k-means statistics engines. It is a sequel to [PT08], [BPRT09], and [PT09] which studied the parallel descriptive, correlative, multi-correlative, principal component analysis, and contingency engines. The ease of use of the new parallel k-means engine is illustrated by the means of C++ code snippets and algorithm verification is provided. This report justifies the design of the statistics engines with parallel scalability in mind, and provides scalability and speed-up analysis results for the k-means engine.

  4. Quantum Statistical Processes in the Early Universe

    E-Print Network [OSTI]

    B. L. Hu

    1993-02-22T23:59:59.000Z

    We show how the concept of quantum open system and the methods in non-equilibrium statistical mechanics can be usefully applied to studies of quantum statistical processes in the early universe. We first sketch how noise, fluctuation, dissipation and decoherence processes arise in a wide range of cosmological problems. We then focus on the origin and nature of noise in quantum fields and spacetime dynamics. We introduce the concept of geometrodynamic noise and suggest a statistical mechanical definition of gravitational entropy. We end with a brief discussion of the theoretical appropriateness to view the physical universe as an open system.

  5. Statistical regimes of random laser fluctuations

    SciTech Connect (OSTI)

    Lepri, Stefano [Istituto dei Sistemi Complessi, Consiglio Nazionale delle Ricerche, via Madonna del Piano 10, I-50019 Sesto Fiorentino (Italy); Cavalieri, Stefano [Dipartimento di Fisica, Universita di Firenze, via G. Sansone 1, I-50019 Sesto Fiorentino (Italy); European Laboratory for Non-linear Spectroscopy, via N. Carrara 1, I-50019 Sesto Fiorentino (Italy); Oppo, Gian-Luca [SUPA and Department of Physics, University of Strathclyde, 107 Rottenrow, Glasgow, G4 0NG, Scotland (United Kingdom); Wiersma, Diederik S. [European Laboratory for Non-linear Spectroscopy, via N. Carrara 1, I-50019 Sesto Fiorentino (Italy); BEC-INFM Center, I-38050 Povo, Trento (Italy)

    2007-06-15T23:59:59.000Z

    Statistical fluctuations of the light emitted from amplifying random media are studied theoretically and numerically. The characteristic scales of the diffusive motion of light lead to Gaussian or power-law (Levy) distributed fluctuations depending on external control parameters. In the Levy regime, the output pulse is highly irregular leading to huge deviations from a mean-field description. Monte Carlo simulations of a simplified model which includes the population of the medium demonstrate the two statistical regimes and provide a comparison with dynamical rate equations. Different statistics of the fluctuations helps to explain recent experimental observations reported in the literature.

  6. On Characterization of Two-Sample U-Statistics

    E-Print Network [OSTI]

    Schechtman, Gideon

    On Characterization of Two-Sample U-Statistics E. Schechtman #3; Department of Industrial@wisdom.weizmann.ac.il Abstract A veri#12;able condition for a symmetric statistic to be a two-sample U-statistic is given. As an illustration, we characterize which linear rank statistics with two-sample regression constants are U-statistics

  7. FISHERY STATISTICS I OF THE UNITED STATESmmmMM

    E-Print Network [OSTI]

    ^^ FISHERY STATISTICS I OF THE UNITED STATESmmmMM 'f^ gjIP^Ws^WI'l STATISTICAL DIGEST NO. 25 Fish Statistical Digest 25 FISHERY STATISTICS OF THE UNITED STATES 1949 BY A. W. ANDERSON and C. E. PETERSON UNITED. Government Printing Office, Washington 25, D. C. - - - Price $1.25 (paper) #12;Fishery Statistics

  8. Photon statistics dispersion in excitonic composites

    E-Print Network [OSTI]

    G. Ya. Slepyan; S. A. Maksimenko

    2006-05-22T23:59:59.000Z

    Linear media are predicted to exist whose relative permiability is an operator in the space of quantum states of light. Such media are characterized by a photon statistics--dependent refractive index. This indicates a new type of optical dispersion -- the photon statistics dispersion. Interaction of quantum light with such media modifies the photon number distribution and, in particular, the degree of coherence of light. An excitonic composite -- a collection of noninteracting quantum dots -- is considered as a realization of the medium with the photon statistics dispersion. Expressions are derived for generalized plane waves in an excitonic composite and input--output relations for a planar layer of the material. Transformation rules for different photon initial states are analyzed. Utilization of the photon statistics dispersion in potential quantum--optical devices is discussed.

  9. Generalized binomial distribution in photon statistics

    E-Print Network [OSTI]

    Aleksey Ilyin

    2014-11-20T23:59:59.000Z

    The photon-number distribution between two parts of a given volume is found for an arbitrary photon statistics. This problem is related to the interaction of a light beam with a macroscopic device, for example a diaphragm, that separates the photon flux into two parts with known probabilities. To solve this problem, a Generalized Binomial Distribution (GBD) is derived that is applicable to an arbitrary photon statistics satisfying probability convolution equations. It is shown that if photons obey Poisson statistics then the GBD is reduced to the ordinary binomial distribution, whereas in the case of Bose-Einstein statistics the GBD is reduced to the Polya distribution. In this case, the photon spatial distribution depends on the phase-space volume occupied by the photons. This result involves a photon bunching effect, or collective behavior of photons that sharply differs from the behavior of classical particles. It is shown that the photon bunching effect looks similar to the quantum interference effect.

  10. Springer Series in Statistics Trevor Hastie

    E-Print Network [OSTI]

    Tibshirani, Robeert

    of Statistical Learning Data Mining,Inference,and Prediction Second Edition #12;This is page v Printer: Opaque. Additive Models, Trees, and Related Methods 10. Boosting and Additive Trees New example from ecology; some

  11. 15.075 Applied Statistics, Spring 2003

    E-Print Network [OSTI]

    Newton, Elizabeth

    This course is an introduction to applied statistics and data analysis. Topics include collecting and exploring data, basic inference, simple and multiple linear regression, analysis of variance, nonparametric methods, and ...

  12. Statistical Risk Estimation for Communication System Design

    E-Print Network [OSTI]

    May 2012 SSL # 6-12 #12;#12;Statistical Risk Estimation for Communication System Design Alessandra Babuscia, David W. Miller May 2012 SSL # 6-12 This work is based on the unaltered text of the thesis

  13. Statistical analysis of correlated fossil fuel securities

    E-Print Network [OSTI]

    Li, Derek Z

    2011-01-01T23:59:59.000Z

    Forecasting the future prices or returns of a security is extraordinarily difficult if not impossible. However, statistical analysis of a basket of highly correlated securities offering a cross-sectional representation of ...

  14. Statistical criteria for characterizing irradiance time series.

    SciTech Connect (OSTI)

    Stein, Joshua S.; Ellis, Abraham; Hansen, Clifford W.

    2010-10-01T23:59:59.000Z

    We propose and examine several statistical criteria for characterizing time series of solar irradiance. Time series of irradiance are used in analyses that seek to quantify the performance of photovoltaic (PV) power systems over time. Time series of irradiance are either measured or are simulated using models. Simulations of irradiance are often calibrated to or generated from statistics for observed irradiance and simulations are validated by comparing the simulation output to the observed irradiance. Criteria used in this comparison should derive from the context of the analyses in which the simulated irradiance is to be used. We examine three statistics that characterize time series and their use as criteria for comparing time series. We demonstrate these statistics using observed irradiance data recorded in August 2007 in Las Vegas, Nevada, and in June 2009 in Albuquerque, New Mexico.

  15. ALICIA L. CARRIQUIRY Department of Statistics

    E-Print Network [OSTI]

    Carriquiry, Alicia

    ., Universidad de la República, Uruguay, December, 1981. EXPERIENCE Associate Provost, (three quarter and Biological Statistics, Universidad de la República del Uruguay, Montevideo, Uruguay, March 2009 to date

  16. Intelligent Transportation Systems Deployment Statistics Database

    E-Print Network [OSTI]

    Intelligent Transportation Systems Deployment Statistics Database Oak Ridge National Laboratory direction. In addition, through the ITS Deployment Tracking web site, the database supports other users in 2010. Users can also download the entire 2010 deployment tracking database through the website

  17. Statistical Models for Next Generation Sequencing Data

    E-Print Network [OSTI]

    Wang, Yiyi

    2013-04-01T23:59:59.000Z

    prior indexed by distances from Gene Ontology (GO). The use of the external biological information yields improvements in statistical power over the original Bayesian discovery procedure. The third model addresses the problem of identifying protein...

  18. Kansas Statistical Abstract 2008 (43rd Edition)

    E-Print Network [OSTI]

    Policy Research Institute

    2009-09-21T23:59:59.000Z

    The Kansas Statistical Abstract contains state, county, and city-level data for Kansas on agriculture, banking and finance, business and exports, climate, communications and information, crime, education, employment and ...

  19. Kansas Statistical Abstract 2009 (44th Edition)

    E-Print Network [OSTI]

    Policy Research Institute

    2011-03-02T23:59:59.000Z

    The Kansas Statistical Abstract contains state, county, and city-level data for Kansas on agriculture, banking and finance, business and exports, climate, communications and information, crime, education, employment and ...

  20. A novel shogaol analog suppresses cancer cell invasion and inflammation, and displays cytoprotective effects through modulation of NF-?B and Nrf2-Keap1 signaling pathways

    SciTech Connect (OSTI)

    Gan, Fei-Fei; Ling, Hui; Ang, Xiaohui; Reddy, Shridhivya A.; Lee, Stephanie S-H.; Yang, Hong; Tan, Sock-Hoon [Department of Pharmacy, Faculty of Science, National University of Singapore (Singapore); Hayes, John D. [Jacqui Wood Cancer Centre, Division of Cancer Research, Ninewells Hospital and Medical School, University of Dundee, Dundee, Scotland (United Kingdom); Chui, Wai-Keung [Department of Pharmacy, Faculty of Science, National University of Singapore (Singapore); Chew, Eng-Hui, E-mail: phaceh@nus.edu.sg [Department of Pharmacy, Faculty of Science, National University of Singapore (Singapore)

    2013-11-01T23:59:59.000Z

    Natural compounds containing vanilloid and Michael acceptor moieties appear to possess anti-cancer and chemopreventive properties. The ginger constituent shogaol represents one such compound. In this study, the anti-cancer potential of a synthetic novel shogaol analog 3-phenyl-3-shogaol (3-Ph-3-SG) was assessed by evaluating its effects on signaling pathways. At non-toxic concentrations, 3-Ph-3-SG suppressed cancer cell invasion in MDA-MB-231 and MCF-7 breast carcinoma cells through inhibition of PMA-activated MMP-9 expression. At similar concentrations, 3-Ph-3-SG reduced expression of the inflammatory mediators nitric oxide (NO), inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2) and prostanglandin-E{sub 2} (PGE{sub 2}) in RAW 264.7 macrophage-like cells. Inhibition of cancer cell invasion and inflammation by 3-Ph-3-SG were mediated through suppression of the nuclear factor-kappaB (NF-?B) signaling pathway. The 3-Ph-3-SG also demonstrated cytoprotective effects by inducing the antioxidant response element (ARE)-driven genes NAD(P)H quinone oxidoreductase-1 (NQO1) and heme oxygenase-1 (HO-1). Cytoprotection by 3-Ph-3-SG was achieved at least partly through modification of cysteine residues in the E3 ubiquitin ligase substrate adaptor Kelch-like ECH-associated protein 1 (Keap1), which resulted in accumulation of transcription factor NF-E2 p45-related factor 2 (Nrf2). The activities of 3-Ph-3-SG were comparable to those of 6-shogaol, the most abundant naturally-occurring shogaol, and stronger than those of 4-hydroxyl-null deshydroxy-3-phenyl-3-shogaol, which attested the importance of the 4-hydroxy substituent in the vanilloid moiety for bioactivity. In summary, 3-Ph-3-SG is shown to possess activities that modulate stress-associated pathways relevant to multiple steps in carcinogenesis. Therefore, it warrants further investigation of this compound as a promising candidate for use in chemotherapeutic and chemopreventive strategies. - Highlights: • Novel shogaol 3-phenyl-3-shogaol suppressed cancer cell invasion and inflammation. • Anti-invasive and anti-inflammatory effects were NF-?B-dependent. • 3-Phenyl-3-shogaol induced ARE-driven genes to achieve cytoprotection. • Cytoprotective effects were brought about by modification of cysteines in Keap1. • Chemopreventive activities of 3-phenyl-3-shogaol and 6-shogaol were comparable.

  1. Microtrenching-free two-step reactive ion etching of 4H-SiC using NF{sub 3}/HBr/O{sub 2} and Cl{sub 2}/O{sub 2}

    SciTech Connect (OSTI)

    Tseng, Yuan-Hung, E-mail: yhtseng.ee99g@nctu.edu.tw; Tsui, Bing-Yue [Department of Electronics Engineering, National Chiao Tung University, No. 1001, Daxue Rd., East Dist., Hsinchu City 30010, Taiwan (China)

    2014-05-15T23:59:59.000Z

    In this paper, the authors performed a reactive ion etch of a 4H-SiC substrate with a gas mixture of NF{sub 3}, HBr, and O{sub 2}, resulting in a microtrenching-free etch. The etch rate was 107.8?nm/min, and the selectivity over the oxide hard mask was ?3.85. Cross-sectional scanning electron microscopy showed no microtrenching compared with etches using plasmas of NF{sub 3}, NF{sub 3}/HBr, and NF{sub 3}/O{sub 2}. Analyzing a variety of HBr/O{sub 2} mixing ratios, the authors discuss the additive effect of each gas and their respective potential mechanisms for alleviating microtrenching. To increase the radius of gyration of the bottom corners, they introduced a second etch step with Cl{sub 2}/O{sub 2} plasma. Fabricating simple metal-oxide-semiconductor capacitors on the two-step etched surface, the authors found that the electrical characteristics of the etched sample were nearly the same as the nonetched sample.

  2. Calibration in High-Energy Astrophysics Statistical Methods

    E-Print Network [OSTI]

    van Dyk, David

    Calibration in High-Energy Astrophysics Statistical Methods Statistical Computation Empirical Illustrations Accounting for Calibration Uncertainty: High Energy Astrophysics and the PCG Sampler David A. van Dyk Accounting for Calibration Uncertainty #12;Calibration in High-Energy Astrophysics Statistical

  3. Indian Agricultural Statistics Research Institute (Indian Council of Agricultural Research)

    E-Print Network [OSTI]

    Rodriguez, Carlos

    #12;Indian Agricultural Statistics Research Institute (Indian Council of Agricultural Research, Indian Agricultural Statistics Research Institute (ICAR), Library Avenue, Pusa, New Delhi-110012 : July 2011 All Rights Reserved 2011, Indian Agricultural Statistics Research Institute (ICAR), New Delhi

  4. Estimating Wireless Network Properties with Spatial Statistics and Models

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Estimating Wireless Network Properties with Spatial Statistics and Models Janne Riihij statistics and models for different estimation problems related to wireless networks. We focus specifically wireless networks. We provide a concise survey of existing techniques from the spatial statistics

  5. Nonparametric Comparison of Densities Based on Statistical Bootstrap

    E-Print Network [OSTI]

    Nonparametric Comparison of Densities Based on Statistical Bootstrap De Brabanter, K.1 , Sahhaf, S. Keywords: Statistical Bootstrap, Variance Stabilization, Least Squares Support Vector Machines, Hypothesis on statistical bootstrap with variance stabilization and a nonparametric kernel density estimator, assisting

  6. Statistical Models for Images: Compression, Restoration and Synthesis

    E-Print Network [OSTI]

    Simoncelli, Eero

    /or nonlinear transfor­ mations, into statistically independent components. The classical approach, and the Sloan Center for Theoretical Neurobiology at NYU. 1. Wavelet Marginal Statistical Model Recently, multiStatistical Models for Images: Compression, Restoration and Synthesis Eero P. Simoncelli Center

  7. "!#$%&'$(0)132"45)(06)7 Mathematics -Math Education -Statistics

    E-Print Network [OSTI]

    Maxwell, Bruce D.

    of the American Statistical Association ­ Marty Hamilton · President's Excellence in Teaching Award ­ Ted Hodgson · Montana Chapter of the American Statistical Association ­ Marty Hamilton - Vice President ­ Sherry Heis ¢¡¤£¦¥¨§©¡© "!#¥$©%&¡'¥$©(0)1¥32"45)¤(0¡6)¤¡¤7 Mathematics - Math Education - Statistics MSU

  8. STANLEY WARNER'S CONTRIBUTIONS TO STATISTICALLY BALANCED INFORMATION TECHNOLOGY

    E-Print Network [OSTI]

    Federation? 3. Should the American Statistical Association adopt a program to certify statisticians? 4 Statistical Association, Stanley Warner first presented the issue of measuring the impact of advocacySTANLEY WARNER'S CONTRIBUTIONS TO STATISTICALLY BALANCED INFORMATION TECHNOLOGY Stephen E. Fienberg

  9. Relation between two-point Green functions of ${\\cal N}=1$ SQED with $N_f$ flavors, regularized by higher derivatives, in the three-loop approximation

    E-Print Network [OSTI]

    A. E. Kazantsev; K. V. Stepanyantz

    2014-10-05T23:59:59.000Z

    We verify the identity which relates the two-point Green functions of ${\\cal N}=1$ SQED with $N_f$ flavors, regularized by higher derivatives, by explicit calculations in the three-loop approximation. This identity explains why in the limit of the vanishing external momentum the two-point Green function of the gauge superfield is given by integrals of double total derivatives in the momentum space. It also allows to derive the NSVZ $\\beta$-function exactly in all loops if the renormalization group functions are defined in terms of the bare coupling constant. In order to verify the considered identity we use it for constructing integrals giving the three-loop $\\beta$-function starting from the two-point Green functions of the matter superfields in the two-loop approximation. Then we demonstrate that the results for these integrals coincide with the sums of the corresponding three-loop supergraphs.

  10. Equi-energy sampler with applications in statistical inference and statistical mechanics

    E-Print Network [OSTI]

    S. C. Kou; Qing Zhou; Wing Hung Wong

    2006-11-08T23:59:59.000Z

    We introduce a new sampling algorithm, the equi-energy sampler, for efficient statistical sampling and estimation. Complementary to the widely used temperature-domain methods, the equi-energy sampler, utilizing the temperature--energy duality, targets the energy directly. The focus on the energy function not only facilitates efficient sampling, but also provides a powerful means for statistical estimation, for example, the calculation of the density of states and microcanonical averages in statistical mechanics. The equi-energy sampler is applied to a variety of problems, including exponential regression in statistics, motif sampling in computational biology and protein folding in biophysics.

  11. 4-Hydroxyestradiol induces oxidative stress and apoptosis in human mammary epithelial cells: possible protection by NF-{kappa}B and ERK/MAPK

    SciTech Connect (OSTI)

    Chen Zhihua [National Research Laboratory of Molecular Carcinogenesis and Chemoprevention, College of Pharmacy, Seoul National University, Shinlim-dong, Kwanak-ku, Seoul 151-742 (Korea, Republic of); Na, Hye-Kyung [National Research Laboratory of Molecular Carcinogenesis and Chemoprevention, College of Pharmacy, Seoul National University, Shinlim-dong, Kwanak-ku, Seoul 151-742 (Korea, Republic of); Hurh, Yeon-Jin [National Research Laboratory of Molecular Carcinogenesis and Chemoprevention, College of Pharmacy, Seoul National University, Shinlim-dong, Kwanak-ku, Seoul 151-742 (Korea, Republic of); Surh, Young-Joon [National Research Laboratory of Molecular Carcinogenesis and Chemoprevention, College of Pharmacy, Seoul National University, Shinlim-dong, Kwanak-ku, Seoul 151-742 (Korea, Republic of)]. E-mail: surh@plaza.snu.ac.kr

    2005-10-01T23:59:59.000Z

    Catechol estrogens, the hydroxylated metabolites of 17{beta}-estradiol (E{sub 2}), have been considered to be implicated in estrogen-induced carcinogenesis. 4-Hydroxyestradiol (4-OHE{sub 2}), an oxidized metabolite of E{sub 2} formed preferentially by cytochrome P450 1B1, reacts with DNA to form depurinating adducts thereby exerting genotoxicity and carcinogenicity. 4-OHE{sub 2} undergoes 2-electron oxidation to quinone via semiquinone, and during this process, reactive oxygen species (ROS) can be generated to cause DNA damage and cell death. In the present study, 4-OHE{sub 2} was found to elicit cytotoxicity in cultured human mammary epithelial (MCF-10A) cells, which was blocked by the antioxidant trolox. MCF-10A cells treated with 4-OHE{sub 2} exhibited increased intracellular ROS accumulation and 8-oxo-7,8-dihydroxy-2'-deoxyguanosine formation, and underwent apoptosis as determined by poly(ADP-ribose)polymerase cleavage and disruption of mitochondrial transmembrane potential. The redox-sensitive transcription factor nuclear factor {kappa}B (NF-{kappa}B) was transiently activated by 4-OHE{sub 2} treatment. Cotreatment of MCF-10A cells with the NF-{kappa}B inhibitor, L-1-tosylamido-2-phenylethyl chloromethyl ketone, exacerbated 4-OHE{sub 2}-induced cell death. 4-OHE{sub 2} also caused transient activation of extracellular signal-regulated protein kinases (ERK) involved in transmitting cell survival or death signals. A pharmacological inhibitor of ERK aggravated the 4-OHE{sub 2}-induced cytotoxicity, supporting the pivotal role of ERK in protecting against catechol estrogen-induced oxidative cell death.

  12. Fact #602: December 21, 2009 Freight Statistics by Mode, 2007...

    Energy Savers [EERE]

    2: December 21, 2009 Freight Statistics by Mode, 2007 Commodity Flow Survey Fact 602: December 21, 2009 Freight Statistics by Mode, 2007 Commodity Flow Survey Results from the...

  13. Bell's fifth position is not supported by supermartingale statistics

    E-Print Network [OSTI]

    J. F. Geurdes

    2013-03-19T23:59:59.000Z

    It is demonstrated that the supermartingale statistics approach of Gill to the CHSH contrast contains a physical (and statistical) unrealistic assumption.

  14. User Statistics Collection Practices Archives | U.S. DOE Office...

    Office of Science (SC) Website

    Policies and Processes User Statistics Collection Practices User Statistics Collection Practices Archives User Facilities User Facilities Home User Facilities at a Glance...

  15. assessment statistical power: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of Statistical Downscaling of GCM Projections Materials Science Websites Summary: Assessment of Statistical Downscaling of GCM Projections for Water Resource Applications...

  16. applying statistical methods: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Methods II Spring 2012 Department of Applied Mathematics and Statistics, CSM Syllabus Fossil Fuels Websites Summary: MATH 531: Statistical Methods II Spring 2012...

  17. Statistical Design, Analysis and Graphics for the Guadalupe

    E-Print Network [OSTI]

    Statistical Design, Analysis and Graphics for the Guadalupe River Assessment Technical Memoranda Science Center (2013). Statistical Design, Analysis and Graphics for the Guadalupe River Assessment

  18. Stochastically Lighting Up Galaxies: Statistical Implications of Stellar Clustering

    E-Print Network [OSTI]

    da Silva, Robert Louis

    2014-01-01T23:59:59.000Z

    SANTA CRUZ STOCHASTICALLY LIGHTING UP GALAXIES: STATISTICAL2 SLUG - Stochastically Lighting Up Galaxies: Methods andx Abstract Stochastically Lighting Up Galaxies: Statistical

  19. Local asymptotic normality in quantum statistics

    E-Print Network [OSTI]

    Madalin Guta; Anna Jencova

    2007-05-24T23:59:59.000Z

    The theory of local asymptotic normality for quantum statistical experiments is developed in the spirit of the classical result from mathematical statistics due to Le Cam. Roughly speaking, local asymptotic normality means that the family varphi_{\\theta_{0}+ u/\\sqrt{n}}^{n} consisting of joint states of n identically prepared quantum systems approaches in a statistical sense a family of Gaussian state phi_{u} of an algebra of canonical commutation relations. The convergence holds for all "local parameters" u\\in R^{m} such that theta=theta_{0}+ u/sqrt{n} parametrizes a neighborhood of a fixed point theta_{0}\\in Theta\\subset R^{m}. In order to prove the result we define weak and strong convergence of quantum statistical experiments which extend to the asymptotic framework the notion of quantum sufficiency introduces by Petz. Along the way we introduce the concept of canonical state of a statistical experiment, and investigate the relation between the two notions of convergence. For reader's convenience and completeness we review the relevant results of the classical as well as the quantum theory.

  20. Tennessee Energy Statistics Quarterly. Second quarter 1984

    SciTech Connect (OSTI)

    Finley, T.F. III; Hensley, B.D.; Trotter, T.

    1985-01-01T23:59:59.000Z

    The Tennessee Energy Statistics Quarterly presents the most current energy statistics available which are specific to the State of Tennessee. In every instance possible, county-level energy data are also shown. The report covers three substantive areas of the energy flow production, consumption, and pricing. The specific energy types for which data are included are coal, petroleum, natural gas and electricity. The Tennessee Energy Statistics Quarterly has been developed by the Tennessee Energy Data Base Program to serve as a supplement to the Energy Division publication - The Tennessee Energy Profiles: 1960-1980. Historical data reported in this volume cover the production and utilization of major energy supplies by fuel type and economic sectors, as well as other energy data such as prices and fuel distribution. 12 figures, 12 tables.

  1. Agile manufacturing from a statistical perspective

    SciTech Connect (OSTI)

    Easterling, R.G. [Sandia National Labs., Albuquerque, NM (United States). New Initiatives Dept.

    1995-10-01T23:59:59.000Z

    The objective of agile manufacturing is to provide the ability to quickly realize high-quality, highly-customized, in-demand products at a cost commensurate with mass production. More broadly, agility in manufacturing, or any other endeavor, is defined as change-proficiency; the ability to thrive in an environment of unpredictable change. This report discusses the general direction of the agile manufacturing initiative, including research programs at the National Institute of Standards and Technology (NIST), the Department of Energy, and other government agencies, but focuses on agile manufacturing from a statistical perspective. The role of statistics can be important because agile manufacturing requires the collection and communication of process characterization and capability information, much of which will be data-based. The statistical community should initiate collaborative work in this important area.

  2. Spin-statistics violations in superstring theory

    SciTech Connect (OSTI)

    Jackson, Mark G. [Particle Astrophysics Center and Theory Group, Fermi National Accelerator Laboratory, Batavia, Illinois 60510 (United States)

    2008-12-15T23:59:59.000Z

    I describe how superstring theory may violate spin statistics in an experimentally observable manner. Reviewing the basics of superstring interactions and how to utilize these to produce a statistical phase, I then apply these ideas to two specific examples. The first is the case of heterotic world sheet linkings, whereby one small closed string momentarily enlarges sufficiently to pass over another, producing such a statistical phase. The second is the braneworld model with noncommutative geometry, whereby matter composed of open strings may couple to a background in which spacetime coordinates do not commute, modifying the field (anti)commutator algebra. I conclude with ways to sharpen and experimentally test these exciting avenues to possibly verify superstring theory.

  3. August 12, 2010 11:8 Journal of Applied Statistics Draft.5 Journal of Applied Statistics

    E-Print Network [OSTI]

    Reed, W.J.

    August 12, 2010 11:8 Journal of Applied Statistics Draft.5 Journal of Applied Statistics Vol. 00 of Victoria, PO Box 3060, Victoria, B.C., Canada V8W 3R4; (July, 2009) A new parametric (3-parameter) survival Taylor & Francis DOI: 10.1080/0266476YYxxxxxxxx http://www.informaworld.com #12;August 12, 2010 11

  4. STATISTICS and PROBABILITY Statistics is the science and practice of developing

    E-Print Network [OSTI]

    Bolch, Tobias

    to understand measurement systems variability, control processes (as #12;in statistical process control or SPC and uncertainty. Origin The word statistics comes from - the modern Latin phrase statisticum collegium (lecture whatever we can observe. This requires us to - plan our observations to control their variability

  5. BS in STATISTICS: Biostatistics Emphasis (695233) MAP Sheet Department of Statistics

    E-Print Network [OSTI]

    Olsen Jr., Dan R.

    121. Complete the following statistics core courses: Stat 123 Introduction to R Programming Stat 124 SAS Base Programming Skills Stat 223 Applied R Programming Stat 224 Applied SAS Programming Stat 230 to Reliability Stat 469 Applied Time Series & Forecasting Stat 497R Introduction to Statistical Research Stat 538

  6. Astrophysical Thermonuclear Functions for Boltzmann-Gibbs Statistics and Tsallis Statistics

    E-Print Network [OSTI]

    R. K. Saxena; A. M. Mathai; H. J. Haubold

    2004-06-22T23:59:59.000Z

    We present an analytic proof of the integrals for astrophysical thermonuclear functions which are derived on the basis of Boltzmann-Gibbs statistical mechanics. Among the four different cases of astrophysical thermonuclear functions, those with a depleted high-energy tail and a cut-off at high energies find a natural interpretation in q-statistics.

  7. On the explanation for quantum statistics

    E-Print Network [OSTI]

    Simon Saunders

    2005-11-15T23:59:59.000Z

    The concept of classical indistinguishability is analyzed and defended against a number of well-known criticisms, with particular attention to the Gibbs' paradox. Granted that it is as much at home in classical as in quantum statistical mechanics, the question arises as to why indistinguishability, in quantum mechanics but not in classical mechanics, forces a change in statistics. The answer, illustrated with simple examples, is that the equilibrium measure on classical phase space is continuous, whilst on Hilbert space it is discrete. The relevance of names, or equivalently, properties stable in time that can be used as names, is also discussed.

  8. Spectral statistics of nearly unidirectional quantum graphs

    E-Print Network [OSTI]

    Maram Akila; Boris Gutkin

    2015-03-04T23:59:59.000Z

    The energy levels of a quantum graph with time reversal symmetry and unidirectional classical dynamics are doubly degenerate and obey the spectral statistics of the Gaussian Unitary Ensemble. These degeneracies, however, are lifted when the unidirectionality is broken in one of the graph's vertices by a singular perturbation. Based on a Random Matrix model we derive an analytic expression for the nearest neighbour distribution between energy levels of such systems. As we demonstrate the result agrees excellently with the actual statistics for graphs with a uniform distribution of eigenfunctions. Yet, it exhibits quite substantial deviations for classes of graphs which show strong scarring.

  9. Spin, Statistics, and Reflections, II. Lorentz Invariance

    E-Print Network [OSTI]

    Bernd Kuckert; Reinhard Lorenzen

    2005-12-21T23:59:59.000Z

    The analysis of the relation between modular P$_1$CT-symmetry -- a consequence of the Unruh effect -- and Pauli's spin-statistics relation is continued. The result in the predecessor to this article is extended to the Lorentz symmetric situation. A model $\\G_L$ of the universal covering $\\widetilde{L_+^\\uparrow}\\cong SL(2,\\complex)$ of the restricted Lorentz group $L_+^\\uparrow$ is modelled as a reflection group at the classical level. Based on this picture, a representation of $\\G_L$ is constructed from pairs of modular P$_1$CT-conjugations, and this representation can easily be verified to satisfy the spin-statistics relation.

  10. Statistical data of the uranium industry

    SciTech Connect (OSTI)

    none,

    1982-01-01T23:59:59.000Z

    Statistical Data of the Uranium Industry is a compendium of information relating to US uranium reserves and potential resources and to exploration, mining, milling, and other activities of the uranium industry through 1981. The statistics are based primarily on data provided voluntarily by the uranium exploration, mining, and milling companies. The compendium has been published annually since 1968 and reflects the basic programs of the Grand Junction Area Office (GJAO) of the US Department of Energy. The production, reserves, and drilling information is reported in a manner which avoids disclosure of proprietary information.

  11. arXiv:physics/001003915Oct2000 Maximally Informative Statistics

    E-Print Network [OSTI]

    George, Edward I.

    arXiv:physics/001003915Oct2000 Maximally Informative Statistics Maximally Informative Statistics: egeorge@mail.utexas.edu Revision history: April 1996. Presented Bayesian Statistics 6, Valencia, 1998 of sufficiency, relevance, and representation. Maximally informative statistics are shown to minimize a Kullback

  12. What can I do with a degree in Statistics?

    E-Print Network [OSTI]

    Hickman, Mark

    What can I do with a degree in Statistics? ENGINEERING Planning your career Choosing a career.canterbury.ac.nz/liaison/best_prep.shtml What is Statistics? Statistics is a rapidly advancing science. It is a very broad subject with many branches. These range from statistical theory to its application in biology, medicine, the social sciences

  13. Statistics Major and Minor www.stat.pitt.edu

    E-Print Network [OSTI]

    Jiang, Huiqiang

    Statistics Major and Minor www.stat.pitt.edu Revised: 10/2012 The field of statistical science decisions in the face of uncertainties. Statistical reasoning is fundamental to research in many scientific. Recent high profile court cases have shown the importance of the use of probability and statistics in law

  14. Chapter 1 The Nature of Probability and Statistics

    E-Print Network [OSTI]

    Hong, Don

    Chapter 1 The Nature of Probability and Statistics 1.1 Introduction Definition. Statistics based on probability theory. This chapter introduces the basic concepts of probability and statistics by answering questions like: · what are the branches of statistics · what are data · how are samples selected 1

  15. Computer Models in Astronomy and Statistics Stellar Evolution

    E-Print Network [OSTI]

    van Dyk, David

    Computer Models in Astronomy and Statistics Stellar Evolution Calibration of X-ray Detectors Embedding Astronomical Computer Models into Complex Statistical Models David A. van Dyk Statistics Section Dyk Complex Analyses with Computer Models in Astronomy #12;Computer Models in Astronomy and Statistics

  16. 1 888 939 3333 | cancer.ca Cancer Statistics

    E-Print Network [OSTI]

    Habib, Ayman

    1 888 939 3333 | cancer.ca Canadian Cancer Statistics 2013 Special topic: Liver cancer Produced by Canadian Cancer Society, Statistics Canada, Public Health Agency of Canada, Provincial/Territorial Cancer Registries cancer.ca/statistics #12;2Canadian Cancer Society n Canadian Cancer Statistics 2013 Citation

  17. David S. Stoffer Department of Statistics [412] 624-8496

    E-Print Network [OSTI]

    , Denver, 2008. Fellow, American Statistical Association, 2006. Recipient of the American Statistical Association's Outstanding Statistical Application Award, 1989. Research award from the Earle C. Anthony FundDavid S. Stoffer Department of Statistics [412] 624-8496 University of Pittsburgh [412] 648

  18. Experiences with a Course on \\Web{Based Statistics"

    E-Print Network [OSTI]

    Symanzik, Jürgen

    Experiences with a Course on \\Web{Based Statistics" Jurgen Symanzik Natascha Vukasinovic Utah State@sunfs.math.usu.edu Abstract Many Statistics courses have been taught that make use of Web{based statistical tools such as teachware tools, electronic textbooks, and statistical software on the Web. However, to our best knowledge

  19. Teaching Experiences with a Course on ``Web--Based Statistics''

    E-Print Network [OSTI]

    Symanzik, Jürgen

    Teaching Experiences with a Course on ``Web--Based Statistics'' J¨urgen Symanzik Natascha@sunfs.math.usu.edu Abstract Many Statistics courses have been taught that make use of Web--based statistical tools such as teachware tools, electronic textbooks, and statistical software on the Web. However, to our best knowledge

  20. Teaching Experiences with a Course on \\Web{Based Statistics"

    E-Print Network [OSTI]

    Symanzik, Jürgen

    Teaching Experiences with a Course on \\Web{Based Statistics" Jurgen Symanzik Natascha Vukasinovic@sunfs.math.usu.edu Abstract Many Statistics courses have been taught that make use of Web{based statistical tools such as teachware tools, electronic textbooks, and statistical software on the Web. However, to our best knowledge

  1. Teaching computing in statistical theory courses David R. Hunter

    E-Print Network [OSTI]

    Hunter, David

    Teaching computing in statistical theory courses David R. Hunter Department of Statistics of Gentle (2004), who states that ". . . all graduate programs in statistics should offer at least one The Pennsylvania State University June 27, 2005 Abstract Graduate-level instruction in statistical computing need

  2. BS in ACTUARIAL SCIENCE (695224) MAP Sheet Department of Statistics

    E-Print Network [OSTI]

    Seamons, Kent E.

    of Statistical Results Stat 330 Introduction to Regression Stat 340 Inference Program Requirements: Complete 496R Academic Internship: Statistics Stat 497R Introduction to Statistical Research RecommendedBS in ACTUARIAL SCIENCE (695224) MAP Sheet Department of Statistics For students entering

  3. 10-702: Statistical Machine Learning Syllabus, Spring 2010

    E-Print Network [OSTI]

    Guestrin, Carlos

    for the course are to be completed using the R programming lan- guage. R is an 10-702: Statistical Machine Learning Syllabus, Spring 2010 http://www.cs.cmu.edu/~10702 Statistical Machine Learning (10-701) and Intermediate Statistics (36-705). The term "statistical" in the title

  4. Linearity -statistics 1.1B training

    E-Print Network [OSTI]

    Linearity - statistics IPAT 1.1B training 300M training D0 resolution is evaluated using 100k single muon events (same events in all 3 plots). Red is the default 11L FTK bank trained using 300M muons on narrow beam of muons (central eta, fixed phi, high fixed pT). Using two types of training: default FTK

  5. INDIAN STATISTICAL INSTITUTE SQC & OR Unit

    E-Print Network [OSTI]

    Bandyopadhyay, Antar

    INDIAN STATISTICAL INSTITUTE SQC & OR Unit Bangalore Announces Certification Program for SIX SIGMA.isi@gmail.com, sanjitisi@yahoo.co.in 6th - 8th, 12th ­ 14th September; 2014 Bangalore #12;EXPECTATION! Six Sigma is like, Dean Witter, Discover & Co. (Report on Business Magazine, October 1997) Six Sigma initiative has

  6. INDIAN STATISTICAL INSTITUTE SQC & OR Unit

    E-Print Network [OSTI]

    Bandyopadhyay, Antar

    INDIAN STATISTICAL INSTITUTE SQC & OR Unit Bangalore Announces Certification Program for SIX SIGMA.isi@gmail.com, sanjitisi@yahoo.co.in #12;EXPECTATION! Six Sigma is like that old Wella Balsam shampoo commercial: `She Magazine, October 1997) Six Sigma initiative has become a rage. Every organization wants to implement Six

  7. Spectral statistics for scaling quantum graphs

    E-Print Network [OSTI]

    Yu. Dabaghian

    2006-08-09T23:59:59.000Z

    The explicit solution to the spectral problem of quantum graphs is used to obtain the exact distributions of several spectral statistics, such as the oscillations of the quantum momentum eigenvalues around the average, $\\delta k_{n}=k_{n}-\\bar k_{n}$, and the nearest neighbor separations, $s_{n}=k_{n}-k_{n-1}$.

  8. Statistical High-Level Synthesis under Process

    E-Print Network [OSTI]

    Giles, C. Lee

    designers is process variability, which causes considerable fluctu- ations in performance and power with variability has be- come one of the major design focuses for nanoscale VLSI design. Traditionally, performanceStatistical High-Level Synthesis under Process Variability Yuan Xie and Yibo Chen Pennsylvania

  9. KALMAN FILTERING WITH STATISTICAL STATE CONSTRAINTS

    E-Print Network [OSTI]

    Simon, Dan

    KALMAN FILTERING WITH STATISTICAL STATE CONSTRAINTS T. L. Chia ControlSoft Inc. 5387 Avion Park with white process and measurement noise, the Kalman ¯lter is known to be the minimum variance linear state estimator. In the case that the random quantities are Gaussian, then the Kalman ¯lter is the minimim

  10. UNIQUE NUMBERS: 04610, 04620 STATISTICS AND MODELING

    E-Print Network [OSTI]

    Ghosh, Joydeep

    . The Statistical Analysis part of the course focuses on determining the existence of relationships between variables and the quantification of such relationships. The main tool we will use to determining the existence of relationships between variables in data and to quantify the strength of the relationships

  11. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    Stephens, Matthew

    of Statistics The University of Chicago Market Efficiency of Crude Oil Futures; A Multivariate Approach THURSDAY, May 12, 2011, at 4:00 PM 110 Eckhart Hall, 5734 S. University Avenue ABSTRACT Crude oil futures commodity, and thus constitute a multivariate framework for describing the cointegrating relationship among

  12. Notes on the MUF-D statistic

    SciTech Connect (OSTI)

    Picard, R.R. (Los Alamos National Lab., NM (USA))

    1987-01-01T23:59:59.000Z

    Verification of an inventory or of a reported material unaccounted for (MUF) calls for the remeasurement of a sample of items by an inspector followed by comparison of the inspector's data to the facility's reported values. Such comparison is intended to protect against falsification of accounting data that could conceal material loss. In the international arena, the observed discrepancies between the inspector's data and the reported data are quantified using the D statistic. If data have been falsified by the facility, the standard deviations of the D and MUF-D statistics are inflated owing to the sampling distribution. Moreover, under certain conditions the distributions of those statistics can depart markedly from normality, complicating evaluation of an inspection plan's performance. Detection probabilities estimated using standard deviations appropriate for the no-falsification case in conjunction with assumed normality can be far too optimistic. Under very general conditions regarding the facility's and/or the inspector's measurement error procedures and the inspector's sampling regime, the variance of the MUF-D statistic can be broken into three components. The inspection's sensitivity against various falsification scenarios can be traced to one or more of these components. Obvious implications exist for the planning of effective inspections, particularly in the area of resource optimization.

  13. MINI-WORKSHOP ANNOUNCEMENT Department of Statistics

    E-Print Network [OSTI]

    Stephens, Matthew

    MINI-WORKSHOP ANNOUNCEMENT Department of Statistics Space-time Modeling of Air Pollution Levels and deposition values of various air pollutants. We propose a space-time modeling approach for combining CMAQ output with observations to produce an improved map of air pollution levels. Methodologies to evaluate

  14. ANOVA and Statistical Models R. A. Bailey

    E-Print Network [OSTI]

    Bailey, R. A.

    ANOVA and Statistical Models R. A. Bailey School of Mathematical Sciences r.a.bailey depends on diet. Model: yield on cow i = KA +i if on diet A KB +i if on diet B KC +i if on diet C where +i if on diet B KC +i if on diet C where 1, ..., 11 are independent (normal) random variables

  15. Wavelet Decomposition Approaches to Statistical Inverse Problems

    E-Print Network [OSTI]

    Abramovich, Felix

    Wavelet Decomposition Approaches to Statistical Inverse Problems BY F. ABRAMOVICH Department alternative is the wavelet­vaguelette decomposition method, based on the expansion of the unknown in wavelet series. In the vaguelette­wavelet decomposition method proposed here, the observed data are expanded

  16. Undergraduate Department of Applied Mathematics and Statistics

    E-Print Network [OSTI]

    Ghosh, Somnath

    of the School of Arts and Sciences or the School of Engineering, respectively, and the departmental requirements be admitted early to concurrent graduate work. The department also offers a Minor in Applied Mathematics and Statistics which is open to undergraduate students majoring in any department of the School of Engineering

  17. Heat pump market and statistics report 2013

    E-Print Network [OSTI]

    Oak Ridge National Laboratory

    #12;Heat pump market and statistics report 2013 Thomas Nowak Secretary General European Heat Pump Summit 15.10./16.10.2013 | Nuremberg #12;European Heat Pump Association (EHPA) · 107 members from 22 countries (status 08/2013) ­ Heat pump manufacturers ­ Component manufacturers ­ National associations

  18. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    Stephens, Matthew

    Department of Statistics The University of Chicago An Empirical Study on Variants of k-Means Clustering which k-means is one of the most mature methods. This paper will talk about its relations with EM and its underlying limitations; an improved k-means algorithm, x-means, will then be discussed

  19. Training Statistics Teachers at Iowa State University*

    E-Print Network [OSTI]

    Froelich, Amy G.

    (intro - agricultural and biological) ­ 5 course instructors. · Stat 226 (intro - business) ­ 5 course Instructors ­ Good evaluations = "promoted" to course instructor. #12;5 Training Process ­ Year 2 · Course · Professors-in-Charge involved in Statistics Education. ­ Current accepted "best" practices ­ Mentoring

  20. Interactive Database Access with Statistics and Graphics

    E-Print Network [OSTI]

    Princeton Plasma Physics Laboratory

    DbAccess The Manual Interactive Database Access with Statistics and Graphics Version 2.1.1 D. M and graphical needs of NSTX Physicists. Flexible views and joins are possible, including options for complex SQL General Atomics (GA Plot Objects) adds extensive graphical and interactive capabilities (and documentation

  1. A Statistical Framework for Spatial Comparative Genomics

    E-Print Network [OSTI]

    A Statistical Framework for Spatial Comparative Genomics Rose Hoberman May 2007 CMU-CS-07, or the U.S. Government. #12;Keywords: spatial comparative genomics, comparative genomics, gene clusters, max-gap clusters, gene teams, whole genome duplication, paralogons, synteny, ortholog detection #12

  2. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    Stephens, Matthew

    and Statistics The University of Chicago GARCH Local Approximation for Non-stationary Financial Data Through 1958 in practice. In this paper, I show that for certain time periods when market is unstable, GARCH model mean square error between locally approximated short- term (ST) GARCH models and long-term (LT) GARCH

  3. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    Stephens, Matthew

    stocks from the alleged internet dot-com episode of 1998­2001, where price bubbles were widely thought Department of Statistics Columbia University Detecting Financial Bubbles in Real Time MONDAY, October 31 the 2007 credit crisis, financial bubbles have once again emerged as a topic of current concern. An open

  4. QUANTUM STATISTICS OF METASTABLE LIQUID HELIUM

    E-Print Network [OSTI]

    Caupin, Frédéric

    QUANTUM STATISTICS OF METASTABLE LIQUID HELIUM FR´ED´ERIC CAUPIN AND S´EBASTIEN BALIBAR Laboratoire in the spinodal line of liquid helium 3, for which experimental evidence has been reported. The calculations in the case of superfluid helium 4; we also consider the overpressurized region, and the location

  5. The University of Chicago Department of Statistics

    E-Print Network [OSTI]

    Stephens, Matthew

    Department of Statistics The University of Chicago Biofuel FeedStock Commodity Pricing FRIDAY, May 13, 2011. We empirically test models using biofuel feedstock commodity futures data traded in CBOT: corn estimation. We answered the questions: whether the prices for biofuel feedstock commodities (corn and soybean

  6. DEPARTMENT OF STATISTICS University of Wisconsin

    E-Print Network [OSTI]

    Chung, Moo K.

    approach. The theoretical construction and the numerical implementation issues are explainedDEPARTMENT OF STATISTICS University of Wisconsin 1300 University Ave. Madison, WI 53706 TECHNICAL-SPHARM generalizes the classical-SPHARM with an additional parameter that modulates the high frequency content

  7. Report on Activities And Usage Statistics of

    E-Print Network [OSTI]

    Patzek, Tadeusz W.

    of the Mobile Learning Portal, at mobilelearningportal.org. This Web site is a #12;Learning Technology CenterReport on Activities And Usage Statistics of Learning Technology Center Services and Facilities 2009-2010 #12;Learning Technology Center Review 2009-2010 December 2010 2 Report on Activities

  8. Remarks on statistical errors in equivalent widths

    E-Print Network [OSTI]

    Klaus Vollmann; Thomas Eversberg

    2006-07-03T23:59:59.000Z

    Equivalent width measurements for rapid line variability in atomic spectral lines are degraded by increasing error bars with shorter exposure times. We derive an expression for the error of the line equivalent width $\\sigma(W_\\lambda)$ with respect to pure photon noise statistics and provide a correction value for previous calculations.

  9. On diagram algebras and statistical mechanics

    E-Print Network [OSTI]

    Haase, Markus

    to discuss relationship structures of towers of diagram algebras statistical mechanical models of many body framework H may have interpretation of Energy (ergodic hypothesis) (as in, the more energy required to sustain a state s, the less likely we are to be in it -- idea being that high energy states are less

  10. STATISTICAL ANALYSIS OF PROTEIN FOLDING KINETICS

    E-Print Network [OSTI]

    Dinner, Aaron

    STATISTICAL ANALYSIS OF PROTEIN FOLDING KINETICS AARON R. DINNER New Chemistry Laboratory for Protein Folding: Advances in Chemical Physics, Volume 120. Edited by Richard A. Friesner. Series Editors Experimental and theoretical studies have led to the emergence of a unified general mechanism for protein

  11. STATISTICS 579 R Tutorial : Programming in R

    E-Print Network [OSTI]

    Fall 2005 STATISTICS 579 R Tutorial : Programming in R 1. Conditional computation in R: The basic control structure available in R for conditional computation is of the form if (cond) expr-1 else expr-2 where cond is an expression that evaluates to a logical value, expr-1 is an R expression

  12. SYLLABUS MATH 7608 STATISTICAL PROGRAMMING WITH R

    E-Print Network [OSTI]

    Hagen, Thomas

    SYLLABUS ­ MATH 7608 STATISTICAL PROGRAMMING WITH R SPRING 2014 11:30- 12:25 MWF DUNN HALL 207:00-4:00 MW or by appointment Textbook: Scientific Programming and Simulation Using R, by Owen Jones, Robert will have a due date assigned and will be turned in via drop box. The program must run in R without error

  13. Statistics of dislocation pinning at localized obstacles

    SciTech Connect (OSTI)

    Dutta, A. [S. N. Bose National Centre for Basic Sciences, Salt Lake, Kolkata 700098 (India); Bhattacharya, M., E-mail: mishreyee@vecc.gov.in; Barat, P. [Variable Energy Cyclotron Centre, 1/AF Bidhannagar, Kolkata 700064 (India)

    2014-10-14T23:59:59.000Z

    Pinning of dislocations at nanosized obstacles like precipitates, voids, and bubbles is a crucial mechanism in the context of phenomena like hardening and creep. The interaction between such an obstacle and a dislocation is often studied at fundamental level by means of analytical tools, atomistic simulations, and finite element methods. Nevertheless, the information extracted from such studies cannot be utilized to its maximum extent on account of insufficient information about the underlying statistics of this process comprising a large number of dislocations and obstacles in a system. Here, we propose a new statistical approach, where the statistics of pinning of dislocations by idealized spherical obstacles is explored by taking into account the generalized size-distribution of the obstacles along with the dislocation density within a three-dimensional framework. Starting with a minimal set of material parameters, the framework employs the method of geometrical statistics with a few simple assumptions compatible with the real physical scenario. The application of this approach, in combination with the knowledge of fundamental dislocation-obstacle interactions, has successfully been demonstrated for dislocation pinning at nanovoids in neutron irradiated type 316-stainless steel in regard to the non-conservative motion of dislocations. An interesting phenomenon of transition from rare pinning to multiple pinning regimes with increasing irradiation temperature is revealed.

  14. Statistical Methods in Surveying by Trilateration

    E-Print Network [OSTI]

    Hereman, Willy A.M.

    positions. In practice, distances are measured with error, and statistical methods can quantify squares technique performs best, but in some situations a linear estimator could in theory be constructed is removed via controlled explosions, both accurate positioning of the drill and precise measurement

  15. Biological Statistics and Computational Biology Seminar Series

    E-Print Network [OSTI]

    Keinan, Alon

    Science and the Center for Computational Biology and Bioinformatics at Columbia University. Dr. PeBiological Statistics and Computational Biology Seminar Series Dr. Itsik Pe'er Associate Professor of Computer Science Columbia University Itsik Pe'er is an associate professor in the Department of Computer

  16. Biological Statistics and Computational Biology Seminar Series

    E-Print Network [OSTI]

    Keinan, Alon

    . Williams Professor of Biomedical Informations and Co-Director, Yale Computational Biology & Bioinformatics co-director of the Yale Computational Biology and Bioinformatics Program. In addition to the KeckBiological Statistics and Computational Biology Seminar Series Dr. Mark B. Gerstein Albert L

  17. The Determinants of Attitudes towards Strategic Default on Mortgages

    E-Print Network [OSTI]

    their house in the Salinas, CA metropolitan statistical area (MSA) in 2006 was -$214,305.2 Unfortunately, we

  18. 2030 Metropolitan Transportation Plan for the Albuquerque Metropolitan Planning Area

    E-Print Network [OSTI]

    Mid-Region Metropolitan Planning Organization

    2007-04-26T23:59:59.000Z

    ...................................................................13-13 #0;#1;#0;#1; #0;5#0;"#0;##0;-#0;4#0;#1; 2-1 Population Density by Municipality, 2000-2004 ..........................................................................................2-2 2-2 Population by Municipality, 2000-2004..........................................................................................................2-3... .....................................................................................14-2 14-2 Neighborhood Association and Community Group MTP Meetings....................................................14-3 #0;#1; #0;'#0;*#0;(#0;6#0;3#0;4#0;#1; 2-1 Residential Building Permits, 1990...

  19. Abilene Metropolitan Area Metropolitan Transportation Plan 2010-2035

    E-Print Network [OSTI]

    Abilene Metropolitan Planning Organization

    2010-01-12T23:59:59.000Z

    City City of Abilene, Texas Class. Classification Col. Collector E. East Equip. Equipment FAA Federal Aviation Administration FHWA Federal Highway Administration FTA Federal Transit Administration FR or fr Frontage Road FM..., Texas Jones County Taylor County Texas Department of Transportation United States Department of Transportation Federal Highway Administration Federal Transit Administration Adopted by Policy Board January 12, 2010 Table...

  20. 2030 Metropolitan Transportation Plan for the Albuquerque Metropolitan Planning Area 

    E-Print Network [OSTI]

    Mid-Region Metropolitan Planning Organization

    2007-04-26T23:59:59.000Z

    ;B#0;O#0;#1;#0;5#0;S#0;B#0;O#0;T#0;Q#0;P#0;S#0;U#0;B#0;U#0;J#0;P#0;O#0;#1;#0;1#0;M#0;B#0;O#0;#1;#0; #0;.#0;5#0;1#0; #0;#1; #0;G#0;P#0;S#0;#1;#0;U#0;I#0;F#0;#1;#0;"#0;M#0;C#0;V#0;R#0;V#0;F#0;S#0;R#0;V#0;F#0;#1;#0;.#0;F#0;U#0;S#0;P#0;Q#0;P#0;M#0;J#0;U#0...#0;#19;#0;#17;#0;#20;#0;#17;#0;#1;#0;.#0;F#0;U#0;S#0;P#0;Q#0;P#0;M#0;J#0;U#0;B#0;O#0;#1;#0;5#0;S#0;B#0;O#0;T#0;Q#0;P#0;S#0;U#0;B#0;U#0;J#0;P#0;O#0;#1;#0;1#0;M#0;B#0;O#0;#1;#0; #0;.#0;5#0;1#0; #0;#1; #0;G#0;P#0;S#0;#1;#0;U#0;I#0;F#0;#1;#0;"#0;M#0;C#0...

  1. Finding Statistics & Data at Queen's Sept/08 STATISTICS Facts & figures in tables, charts, time series, graphs, etc.

    E-Print Network [OSTI]

    Abolmaesumi, Purang

    Finding Statistics & Data at Queen's Sept/08 STATISTICS Facts & figures in tables, charts, time series, graphs, etc. 1. Statistics Canada www.statcan.ca English use the search box... REMEMBER: Don't Pay Contact madgic@queensu.ca to get statistics for free if faced with a fee! 2. Social

  2. ENGI 4421 Descriptive Statistics Page 1-01 A Brief Definition of "Statistics": [Navidi Chapter 1 & Devore Chapter 1

    E-Print Network [OSTI]

    George, Glyn

    & Devore Chapter 1] "Statistics" is the science of making decisions in the absence of certainty. . Some Probability Devore Ch. 2-6; Navidi Ch. 2-4 Notes Ch. 2-11 Inferential Statistics Devore Ch. 7-9, 12, 14ENGI 4421 Descriptive Statistics Page 1-01 A Brief Definition of "Statistics": [Navidi Chapter 1

  3. Summary Recommendations of Review of Statistical Research Methods Training and Research Support (including the Statistical Consulting Unit)

    E-Print Network [OSTI]

    Botea, Adi

    (including the Statistical Consulting Unit) Training in statistics for postgraduates R1: The senior a co-ordinated approach to the statistical training of postgraduate students. R2: If the senior, and which is designed to capture postgraduates in programs where statistics training is not routinely

  4. 8.333 Statistical Mechanics I: Statistical Mechanics of Particles, Fall 2007

    E-Print Network [OSTI]

    Kardar, Mehran

    Statistical Mechanics is a probabilistic approach to equilibrium properties of large numbers of degrees of freedom. In this two-semester course, basic principles are examined. Topics include: thermodynamics, probability ...

  5. 8.333 Statistical Mechanics I: Statistical Mechanics of Particles, Fall 2005

    E-Print Network [OSTI]

    Kardar, Mehran

    Statistical Mechanics is a probabilistic approach to equilibrium properties of large numbers of degrees of freedom. In this two-semester course, basic principles are examined. Topics include: thermodynamics, probability ...

  6. 8.334 Statistical Mechanics II: Statistical Physics of Fields, Spring 2008

    E-Print Network [OSTI]

    Kardar, Mehran

    This is the second term in a two-semester course on statistical mechanics. Basic principles are examined in 8.334, such as the laws of thermodynamics and the concepts of temperature, work, heat, and entropy. Topics from ...

  7. MANCHESTER METROPOLITAN DISABILITY EQUALITY SCHEME

    E-Print Network [OSTI]

    assessment following the creation of a dedicated Equalities Impact Assessment (EIA) team. In order to keep up has been made a priority for the Equalities and EIA teams by the Development & Training Manager

  8. MANCHESTER METROPOLITAN UNIVERSITY POLICY FRAMEWORK

    E-Print Network [OSTI]

    AND ACADEMIC SERVICES GOVERNANCE AND SECRETARIAT TEAM POLICY FRAMEWORK AND EQUALITY IMPACT ASSESSMENT (EIA date, date EIA approved, approval body and review date. Other points to consider include: Additional

  9. Mobility 2035 Metropolitan Transportation Plan

    E-Print Network [OSTI]

    Killeen-Temple Urban Transportation Study

    2009-05-20T23:59:59.000Z

    totality to include the ecological, physical (natural and manmade), social, political, aesthetic, and economic environments.? The Federal Highway Administration (FHWA) defines three basic principles of environmental justice: ? Avoid, minimize... ............................................................................................................... 2 Creation of Mobility 2035 and Who is Involved ...................................................................................... 2 Federal and State Requirements...

  10. Prepared for: New York Metropolitan

    E-Print Network [OSTI]

    Qiu, Weigang

    .............................................................................................................................2-2 Power................................................................................................................................2-2 Purchase Recommendations

  11. a sustainable Manchester Metropolitan University

    E-Print Network [OSTI]

    Management Plan which has been used as an exemplar of best practice across the public sector by the Carbon of student demand and consequent financial sustainability. Despite this, MMU remains in a strong position commitment to environmental responsibility; we remain determined to lead the sector in attaining

  12. Metropolitan Landfill Abatement Act (Minnesota)

    Broader source: Energy.gov [DOE]

    A fee is imposed on operators of mixed municipal solid waste disposal facilities corresponding to the amount of waste taken in. Waste residue from recycling facilities or resource recovery...

  13. Manchester Metropolitan University Travel Plan

    E-Print Network [OSTI]

    by providing more assistance to staff who are considering sharing car journeys, switching to public transport with the introduction of schemes to facilitate car sharing and the purchase of discounted season tickets on public.2 Measures to Reduce Car Use...............................................................................9

  14. San Angelo Metropolitan Transportation Plan

    E-Print Network [OSTI]

    San Angelo Metropolitan Planning Organization

    2009-11-16T23:59:59.000Z

    : City of San Angelo Tom Green County Concho Valley Transit District Texas Department of Transportation U.S. Department of Transportation Federal Highway Administration Federal Transit Administration Approved... Director Concho Valley Council of Governments * Elected Non-Voting Members Drew Darby* State Representative, State of Texas Robert Duncan* State Senator, State of Texas Peggy Thurin Statewide Planning Coordinator...

  15. Consequences of Flooding on Spectral Statistics

    E-Print Network [OSTI]

    Torsten Rudolf; Normann Mertig; Steffen Löck; Arnd Bäcker

    2012-04-05T23:59:59.000Z

    We study spectral statistics in systems with a mixed phase space, in which regions of regular and chaotic motion coexist. Increasing their density of states, we observe a transition of the level-spacing distribution P(s) from Berry-Robnik to Wigner statistics, although the underlying classical phase-space structure and the effective Planck constant remain unchanged. This transition is induced by flooding, i.e., the disappearance of regular states due to increasing regular-to-chaotic couplings. We account for this effect by a flooding-improved Berry-Robnik distribution, in which an effectively reduced size of the regular island enters. To additionally describe power-law level repulsion at small spacings, we extend this prediction by explicitly considering the tunneling couplings between regular and chaotic states. This results in a flooding- and tunneling-improved Berry-Robnik distribution which is in excellent agreement with numerical data.

  16. Mathematical and Statistical Opportunities in Cyber Security

    SciTech Connect (OSTI)

    Meza, Juan; Campbell, Scott; Bailey, David

    2009-03-23T23:59:59.000Z

    The role of mathematics in a complex system such as the Internet has yet to be deeply explored. In this paper, we summarize some of the important and pressing problems in cyber security from the viewpoint of open science environments. We start by posing the question 'What fundamental problems exist within cyber security research that can be helped by advanced mathematics and statistics'? Our first and most important assumption is that access to real-world data is necessary to understand large and complex systems like the Internet. Our second assumption is that many proposed cyber security solutions could critically damage both the openness and the productivity of scientific research. After examining a range of cyber security problems, we come to the conclusion that the field of cyber security poses a rich set of new and exciting research opportunities for the mathematical and statistical sciences.

  17. Statistical Mechanical Models and Topological Color Codes

    E-Print Network [OSTI]

    H. Bombin; M. A. Martin-Delgado

    2007-11-03T23:59:59.000Z

    We find that the overlapping of a topological quantum color code state, representing a quantum memory, with a factorized state of qubits can be written as the partition function of a 3-body classical Ising model on triangular or Union Jack lattices. This mapping allows us to test that different computational capabilities of color codes correspond to qualitatively different universality classes of their associated classical spin models. By generalizing these statistical mechanical models for arbitrary inhomogeneous and complex couplings, it is possible to study a measurement-based quantum computation with a color code state and we find that their classical simulatability remains an open problem. We complement the meaurement-based computation with the construction of a cluster state that yields the topological color code and this also gives the possibility to represent statistical models with external magnetic fields.

  18. Statistical approach to nuclear level density

    SciTech Connect (OSTI)

    Sen'kov, R. A.; Horoi, M. [Department of Physics, Central Michigan University, Mount Pleasant, MI 48859 (United States); Zelevinsky, V. G. [Department of Physics and Astronomy and National Superconducting Cyclotron Laboratory, Michigan State University, East Lansing, MI 48824-1321 (United States)

    2014-10-15T23:59:59.000Z

    We discuss the level density in a finite many-body system with strong interaction between the constituents. Our primary object of applications is the atomic nucleus but the same techniques can be applied to other mesoscopic systems. We calculate and compare nuclear level densities for given quantum numbers obtained by different methods, such as nuclear shell model (the most successful microscopic approach), our main instrument - moments method (statistical approach), and Fermi-gas model; the calculation with the moments method can use any shell-model Hamiltonian excluding the spurious states of the center-of-mass motion. Our goal is to investigate statistical properties of nuclear level density, define its phenomenological parameters, and offer an affordable and reliable way of calculation.

  19. New paradigms for the statistics profession

    SciTech Connect (OSTI)

    Iman, R.L.

    1995-02-01T23:59:59.000Z

    This paper is a presentation made in support of the statistics profession. This field can say it has had a major impact in most major fields of study presently undertaken by man, yet it is not perceived as an important, or critical field of study. It is not a growth field either, witness the almost level number of faculty and new PhD`s produced over the past twenty years. The author argues the profession must do a better job of selling itself to the students it educates. Awaken them to the impact of statistics in their lives and their business worlds, so that they see beyond the formulae to the application of these principles.

  20. Robust statistical reconstruction for charged particle tomography

    DOE Patents [OSTI]

    2013-10-08T23:59:59.000Z

    Systems and methods for charged particle detection including statistical reconstruction of object volume scattering density profiles from charged particle tomographic data to determine the probability distribution of charged particle scattering using a statistical multiple scattering model and determine a substantially maximum likelihood estimate of object volume scattering density using expectation maximization (ML/EM) algorithm to reconstruct the object volume scattering density. The presence of and/or type of object occupying the volume of interest can be identified from the reconstructed volume scattering density profile. The charged particle tomographic data can be cosmic ray muon tomographic data from a muon tracker for scanning packages, containers, vehicles or cargo. The method can be implemented using a computer program which is executable on a computer.

  1. A different approach to introducing statistical mechanics

    E-Print Network [OSTI]

    Moore, Thomas A

    2015-01-01T23:59:59.000Z

    The basic notions of statistical mechanics (microstates, multiplicities) are quite simple, but understanding how the second law arises from these ideas requires working with cumbersomely large numbers. To avoid getting bogged down in mathematics, one can compute multiplicities numerically for a simple model system such as an Einstein solid -- a collection of identical quantum harmonic oscillators. A computer spreadsheet program or comparable software can compute the required combinatoric functions for systems containing a few hundred oscillators and units of energy. When two such systems can exchange energy, one immediately sees that some configurations are overwhelmingly more probable than others. Graphs of entropy vs. energy for the two systems can be used to motivate the theoretical definition of temperature, $T= (\\partial S/\\partial U)^{-1}$, thus bridging the gap between the classical and statistical approaches to entropy. Further spreadsheet exercises can be used to compute the heat capacity of an Einst...

  2. Emergent irreversibility and entanglement spectrum statistics

    E-Print Network [OSTI]

    Claudio Chamon; Alioscia Hamma; Eduardo R. Mucciolo

    2014-06-24T23:59:59.000Z

    We study the problem of irreversibility when the dynamical evolution of a many-body system is described by a stochastic quantum circuit. Such evolution is more general than a Hamiltonian one, and since energy levels are not well defined, the well-established connection between the statistical fluctuations of the energy spectrum and irreversibility cannot be made. We show that the entanglement spectrum provides a more general connection. Irreversibility is marked by a failure of a disentangling algorithm and is preceded by the appearance of Wigner-Dyson statistical fluctuations in the entanglement spectrum. This analysis can be done at the wave-function level and offers an alternative route to study quantum chaos and quantum integrability.

  3. Professor C. N. Yang and Statistical Mechanics

    E-Print Network [OSTI]

    F. Y. Wu

    2010-10-09T23:59:59.000Z

    Professor Chen Ning Yang has made seminal and influential contributions in many different areas in theoretical physics. This talk focuses on his contributions in statistical mechanics, a field in which Professor Yang has held a continual interest for over sixty years. His Master's thesis was on a theory of binary alloys with multi-site interactions, some 30 years before others studied the problem. Likewise, his other works opened the door and led to subsequent developments in many areas of modern day statistical mechanics and mathematical physics. He made seminal contributions in a wide array of topics, ranging from the fundamental theory of phase transitions, the Ising model, Heisenberg spin chains, lattice models, and the Yang-Baxter equation, to the emergence of Yangian in quantum groups. These topics and their ramifications will be discussed in this talk.

  4. Statistical Issues in Searches for New Physics

    E-Print Network [OSTI]

    Louis Lyons

    2014-09-05T23:59:59.000Z

    Given the cost, both financial and even more importantly in terms of human effort, in building High Energy Physics accelerators and detectors and running them, it is important to use good statistical techniques in analysing data. Some of the statistical issues that arise in searches for New Physics are discussed briefly. They include topics such as: Should we insist on the 5 sigma criterion for discovery claims? The probability of A, given B, is not the same as the probability of B, given A. The meaning of p-values. What is Wilks Theorem and when does it not apply? How should we deal with the `Look Elsewhere Effect'? Dealing with systematics such as background parametrisation. Coverage: What is it and does my method have the correct coverage? The use of p0 versus p1 plots.

  5. ASTROPHYSICAL FLUID DYNAMICS VIA DIRECT STATISTICAL SIMULATION

    SciTech Connect (OSTI)

    Tobias, S. M. [Department of Applied Mathematics, University of Leeds, Leeds LS2 9JT (United Kingdom); Dagon, K.; Marston, J. B., E-mail: smt@maths.leeds.ac.uk [Department of Physics, Brown University, Providence, RI 02912-1843 (United States)

    2011-02-01T23:59:59.000Z

    In this paper, we introduce the concept of direct statistical simulation for astrophysical flows. This technique may be appropriate for problems in astrophysical fluids where the instantaneous dynamics of the flows are of secondary importance to their statistical properties. We give examples of such problems including mixing and transport in planets, stars, and disks. The method is described for a general set of evolution equations, before we consider the specific case of a spectral method optimized for problems on a spherical surface. The method is illustrated for the simplest non-trivial example of hydrodynamics and magnetohydrodynamics on a rotating spherical surface. We then discuss possible extensions of the method both in terms of computational methods and the range of astrophysical problems that are of interest.

  6. Statistical review of coal in Canada, 1997

    SciTech Connect (OSTI)

    Not Available

    1999-01-01T23:59:59.000Z

    The paper presents an annual review of the coal industry, including production, exports and imports, and consumption. An overview is given, followed by more detailed statistical data for the current year and preceding decade (supply and demand, value and volume of supply by province, coal production by class or province, exports by destination, coal consumed in power generation by province, electrical energy production by fuel type, domestic demand for primary energy by type).

  7. Spectral statistics for weakly correlated random potentials

    E-Print Network [OSTI]

    Frédéric Klopp

    2012-10-29T23:59:59.000Z

    We study localization and derive stochastic estimates (in particular, Wegner and Minami estimates) for the eigenvalues of weakly correlated random discrete Schr\\"odinger operators in the localized phase. We apply these results to obtain spectral statistics for general discrete alloy type models where the single site perturbation is neither of finite rank nor of fixed sign. In particular, for the models under study, the random potential exhibits correlations at any range.

  8. A comparison of D statistic approaches

    SciTech Connect (OSTI)

    Franklin, M. [Commission of the European Communities, Ispra (Italy). Joint Research Centre

    1993-12-31T23:59:59.000Z

    This paper compares the traditional D statistic with a ratio estimator (R) of the true material discrepancy in the verification of nuclear material accounts. The purpose of the paper is to discuss whether there is any practical advantage in using R in place of D. The paper discusses D and R in terms of bias, standard deviation and its` estimation, reliability of confidence intervals and information requirements for implementation.

  9. ANOVA and Statistical Models R. A. Bailey

    E-Print Network [OSTI]

    Bailey, R. A.

    ANOVA and Statistical Models R. A. Bailey School of Mathematical Sciences r.a.bailey@qmul.ac.uk ESD on cow i = KA +i if on diet A KB +i if on diet B KC +i if on diet C where 1, ..., 11 are independent: yield depends on diet. Model: yield on cow i = KA +i if on diet A KB +i if on diet B KC +i if on diet

  10. Statistical analysis in multispectral remote sensing

    E-Print Network [OSTI]

    Albert, Walter Gerald

    1970-01-01T23:59:59.000Z

    and examines various statistical techniques for their usefulness in crop pre- diction. These techniques include multiple regression, discriminant analysis, and likelihood ratio tests. Other procedures employed in this paper are univsriate and multivariate... analysis of variance. Several transformations are performed on the data, sets in an attempt to increase accuracy for discrimination of crops, Conclu- sions of the work undertaken in this paper are presented, and recommendations are made for further...

  11. Nature of Roberge-Weiss transition end points for heavy quarks in $N_f=2$ lattice QCD with Wilson fermions

    E-Print Network [OSTI]

    Liang-Kai Wu; Xiang-Fei Meng

    2014-10-26T23:59:59.000Z

    The phase structure of QCD with imaginary chemical potential provides information on the phase diagram of QCD with real chemical potential. With imaginary chemical potential $i\\mu_I=i\\pi T$, previous studies show that the Roberge-Weiss (RW) transition end points are triple points at both large and small quark masses, and second order transition points at intermediate quark masses. The triple and second order end points are separated by two tricritical ones. We present simulations with $ N_f=2 $ Wilson fermions to investigate the nature of RW transition end points. The simulations are carried out at 8 values of the hopping parameter $\\kappa$ ranging from 0.020 to 0.140 on different lattice volumes. The Binder cumulant, susceptibility and reweighted distribution of the imaginary part of Polyakov loop are employed to determine the nature of RW transition end points. The simulations show that the two tricritical points are within the range $0.070-0.080$ and $0.120-0.140$, respectively.

  12. Measurement of the F2n/F2p and d/u Ratios in Deep Inelastic Electron Scattering off 3H and 3He

    E-Print Network [OSTI]

    G. G. Petratos; I. R. Afnan; F. Bissey; J. Gomez; A. T. Katramatou; W. Melnitchouk; A. W. Thomas

    2000-10-19T23:59:59.000Z

    We discuss a possible measurement of the ratio of the nucleon structure functions, F2n/F2p, and the ratio of the up to down quark distributions, u/d, at large x, by performing deep inelastic electron scattering from the 3H and 3He mirror nuclei with the 11 GeV upgraded beam of Jefferson Lab. The measurement is expected to be almost free of nuclear effects, which introduce a significant uncertainty in the extraction of these two ratios from deep inelastic scattering off the proton and deuteron. The results are expected to test perturbative and non-perturbative mechanisms of spin-flavor symmetry breaking in the nucleon, and constrain the structure function parameterizations needed for the interpretation of high energy e-p, p-p and p-pbar collider data. The precision of the expected data can also allow for testing competing parameterizations of the nuclear EMC effect and provide valuable constraints on models of its dynamical origin.

  13. Lattice NRQCD study of S- and P-wave bottomonium states in a thermal medium with $N_f=2+1$ light flavors

    E-Print Network [OSTI]

    Seyong Kim; Peter Petreczky; Alexander Rothkopf

    2014-09-12T23:59:59.000Z

    We investigate the properties of S-and P-wave bottomonium states in the vicinity of the deconfinement transition temperature. The light degrees of freedom are represented by dynamical lattice QCD configurations of the HotQCD collaboration with $N_f = 2 + 1$ flavors. Bottomonium correlators are obtained from bottom quark propagators, computed in Non-Relativistic QCD (NRQCD) under the background of these gauge field configurations. The spectral functions for the $^3S_1$ ($\\Upsilon$) and $^3P_1$ ($\\chi_{b1}$) channel are extracted from the Euclidean time correlators using a novel Bayesian approach in the temperature region $140 {\\rm MeV} \\le T \\le 249 {\\rm MeV}$ and the results are contrasted to those from the standard Maximum Entropy Method. We find that the new Bayesian approach is far superior to the Maximum Entropy Method and enables us to study reliably the first peak in the spectral functions even under the limitations present in the finite temperature setup. We find that $\\chi_{b1}$ survives up to $T=249 {\\rm MeV}$, the highest temperature considered in our study and put stringent constraints on the size of the medium modification of $\\Upsilon$ and $\\chi_{b1}$ states.

  14. Weatherization Assistance Program - Background Data and Statistics

    SciTech Connect (OSTI)

    Eisenberg, Joel Fred [ORNL

    2010-03-01T23:59:59.000Z

    This technical memorandum is intended to provide readers with information that may be useful in understanding the purposes, performance, and outcomes of the Department of Energy's (DOE's) Weatherization Assistance Program (Weatherization). Weatherization has been in operation for over thirty years and is the nation's largest single residential energy efficiency program. Its primary purpose, established by law, is 'to increase the energy efficiency of dwellings owned or occupied by low-income persons, reduce their total residential energy expenditures, and improve their health and safety, especially low-income persons who are particularly vulnerable such as the elderly, the handicapped, and children.' The American Reinvestment and Recovery Act PL111-5 (ARRA), passed and signed into law in February 2009, committed $5 Billion over two years to an expanded Weatherization Assistance Program. This has created substantial interest in the program, the population it serves, the energy and cost savings it produces, and its cost-effectiveness. This memorandum is intended to address the need for this kind of information. Statistically valid answers to many of the questions surrounding Weatherization and its performance require comprehensive evaluation of the program. DOE is undertaking precisely this kind of independent evaluation in order to ascertain program effectiveness and to improve its performance. Results of this evaluation effort will begin to emerge in late 2010 and 2011, but they require substantial time and effort. In the meantime, the data and statistics in this memorandum can provide reasonable and transparent estimates of key program characteristics. The memorandum is laid out in three sections. The first deals with some key characteristics describing low-income energy consumption and expenditures. The second section provides estimates of energy savings and energy bill reductions that the program can reasonably be presumed to be producing. The third section deals with estimates of program cost-effectiveness and societal impacts such as carbon reduction and reduced national energy consumption. Each of the sections is brief, containing statistics, explanatory graphics and tables as appropriate, and short explanations of the statistics in order to place them in context for the reader. The companion appendices at the back of the memorandum explain the methods and sources used in developing the statistics.

  15. A tree-to-tree model for statistical machine translation

    E-Print Network [OSTI]

    Cowan, Brooke A. (Brooke Alissa), 1972-

    2008-01-01T23:59:59.000Z

    In this thesis, we take a statistical tree-to-tree approach to solving the problem of machine translation (MT). In a statistical tree-to-tree approach, first the source-language input is parsed into a syntactic tree ...

  16. STATISTICAL MODELS FOR MULTIPLE SEQUENCE ALIGNMENT: UNIFICATIONS AND GENERALIZATIONS

    E-Print Network [OSTI]

    Liu, Jun

    , Stanford University; Charles E. Lawrence, NYS­DOH Jun S. Liu, Department of Statistics, Stanford University and our main point of interest. We believe that building explicit statistical model is an important

  17. Outline of the talk Statistics on Graphs, Exponential Formula and

    E-Print Network [OSTI]

    Poinsot, Laurent

    Outline of the talk Statistics on Graphs, Exponential Formula and Combinatorial Physics G and Complexity" Laurent Poinsot Statistics on Graphs, Exponential Formula and Combinatorial Physics #12;Exponential Formula : Informal Version Ingredients for the exponential formula Partial commutative monoids

  18. Statistical estimation of water distribution system pipe break risk

    E-Print Network [OSTI]

    Yamijala, Shridhar

    2009-05-15T23:59:59.000Z

    and maintenance decisions. A number of statistical methods have been proposed for this estimation problem. This thesis focuses on comparing these statistical models on the basis of short time histories. The goals of this research are to estimate the likelihood...

  19. Cloud-Based Statistical Analysis from Users' Perspective Botong Huang

    E-Print Network [OSTI]

    Yang, Jun

    efficient statistical analysis programs requires tremendous expertise and effort. Most statisticians would much prefer programming in languages familiar to them, such as R and MATLAB, Copyright 2014 IEEECumulon: Cloud-Based Statistical Analysis from Users' Perspective Botong Huang Department

  20. university-logo Introduction to Statistical Machine Translation

    E-Print Network [OSTI]

    Goldschmidt, Christina

    university-logo . . . . . . Introduction to Statistical Machine Translation Phil Blunsom phil Week 6 1 / 47 #12;university-logo . . . . . . Outline . ..1 Introduction . ..2 Parallel corpora . ..3) Statistical Machine Translation Michaelmas Week 6 2 / 47 #12;university-logo . . . . . . Outline . ..1

  1. REANALYSIS OF F-STATISTIC GRAVITATIONAL-WAVE SEARCHES WITH THE HIGHER CRITICISM STATISTIC

    SciTech Connect (OSTI)

    Bennett, M. F.; Melatos, A. [School of Physics, University of Melbourne, Parkville, VIC 3010 (Australia)] [School of Physics, University of Melbourne, Parkville, VIC 3010 (Australia); Delaigle, A.; Hall, P., E-mail: mfb@unimelb.edu.au [Department of Mathematics and Statistics, University of Melbourne, Parkville, VIC 3010 (Australia)

    2013-04-01T23:59:59.000Z

    We propose a new method of gravitational-wave detection using a modified form of higher criticism, a statistical technique introduced by Donoho and Jin. Higher criticism is designed to detect a group of sparse, weak sources, none of which are strong enough to be reliably estimated or detected individually. We apply higher criticism as a second-pass method to synthetic F-statistic and C-statistic data for a monochromatic periodic source in a binary system and quantify the improvement relative to the first-pass methods. We find that higher criticism on C-statistic data is more sensitive by {approx}6% than the C-statistic alone under optimal conditions (i.e., binary orbit known exactly) and the relative advantage increases as the error in the orbital parameters increases. Higher criticism is robust even when the source is not monochromatic (e.g., phase-wandering in an accreting system). Applying higher criticism to a phase-wandering source over multiple time intervals gives a {approx}> 30% increase in detectability with few assumptions about the frequency evolution. By contrast, in all-sky searches for unknown periodic sources, which are dominated by the brightest source, second-pass higher criticism does not provide any benefits over a first-pass search.

  2. ORIGINAL ARTICLE Quantification of the Statistical Effects of Spatiotemporal

    E-Print Network [OSTI]

    Rowe, Daniel B.

    that such operations have on the statistical properties of the acquired data are unaccounted for, neuroscientists could

  3. Statistical Properties of the Cluster Dynamics of the Systems of ...

    E-Print Network [OSTI]

    1910-70-12T23:59:59.000Z

    Landau Institute of Theoretical Physics, Moscow, Russia. §. Department of Mathematics and Statistics, University of Nevada, Reno, NV 89557,. USA ...

  4. Statistics from Lagrangian observations J.H. LaCasce *

    E-Print Network [OSTI]

    LaCasce, Joseph H.

    Review Statistics from Lagrangian observations J.H. LaCasce * Department of Geosciences, University February 2008 Keywords: Lagrangian statistics Floats Drifters Absolute and relative dispersion a b s t r a c t We review statistical analyses of Lagrangian data from the ocean. These can be grouped

  5. Statistics Twentyfirst Century Astrometry K. Eichhorn Memorial Lecture

    E-Print Network [OSTI]

    Jefferys, William

    Statistics Twenty­first Century Astrometry Heinrich K. Eichhorn Memorial Lecture William Je#erys (bill@astro.as.utexas.edu University at Austin, Abstract. Eichhorn statistics scientific a number of significant contributions statistical treatment of astrometric problems. a movement for the reintroduction

  6. Photon statistics: Nonlinear spectroscopy of single quantum systems Shaul Mukamel

    E-Print Network [OSTI]

    Mukamel, Shaul

    Photon statistics: Nonlinear spectroscopy of single quantum systems Shaul Mukamel Department of their infor- mation content. A general formal expression for photon counting statistics from single quantum counting statistics which had proven to be a most valuable measure of coherence has been formulated

  7. Statistics for Analysis of Experimental Data Catherine A. Peters

    E-Print Network [OSTI]

    Peters, Catherine A.

    Statistics for Analysis of Experimental Data Catherine A. Peters Department of Civil Engineering Processes Laboratory Manual S. E. Powers, Ed. AEESP, Champaign, IL 2001 1 #12;Statistics Princeton University Princeton, NJ 08544 Statistics is a mathematical tool for quantitative analysis of data

  8. Online Course Syllabus STATS 8: Introduction to Biological Statistics

    E-Print Network [OSTI]

    Loudon, Catherine

    Online Course Syllabus Page 1 STATS 8: Introduction to Biological Statistics Summer Session II 2011. Baldi is a lecturer at UC Irvine where she has been teaching statistics for many years. She is also involved in the development of educational material for statistics, from helping to conceive a TV program

  9. Helping Doctors and Patients Make Sense of Health Statistics

    E-Print Network [OSTI]

    Heubach, Silvia

    Helping Doctors and Patients Make Sense of Health Statistics Gerd Gigerenzer,1,2 Wolfgang, patients, journalists, and politi- cians alike do not understand what health statistics mean or draw wrong conclusions without noticing. Collective statistical illiteracy refers to the widespread inability

  10. DATA MINING AT THE INTERFACE OF COMPUTER SCIENCE AND STATISTICS

    E-Print Network [OSTI]

    Smyth, Padhraic

    Chapter 1 DATA MINING AT THE INTERFACE OF COMPUTER SCIENCE AND STATISTICS \\Lambda Padhraic Smyth a better understanding of the role of statistical thinking in modern data mining. Data mining has at the application of a variety of techniques from both computer science and statistics. The chapter discusses how

  11. Explicit Expressions for Moments of Log Normal Order Statistics

    E-Print Network [OSTI]

    Sidorov, Nikita

    Explicit Expressions for Moments of Log Normal Order Statistics Saralees Nadarajah First version: 31 December 2006 Research Report No. 23, 2006, Probability and Statistics Group School of Mathematics, The University of Manchester #12;Explicit Expressions for Moments of Log Normal Order Statistics by Saralees

  12. Gille-SIO 221C 1 Objective Mapping: Anisotropic Statistics

    E-Print Network [OSTI]

    Gille, Sarah T.

    Gille-SIO 221C 1 Objective Mapping: Anisotropic Statistics Objective mapping discussions often assume that covariance statistics are isotropic and homogeneous. However, in the ocean and atmosphere. The equations used to carry out objective mapping are easily modified to allow for anisotropic statistics

  13. RSM 512 Statistics for Environmental Management Instructor: Elizabeth A. Babcock

    E-Print Network [OSTI]

    Miami, University of

    RSM 512 Statistics for Environmental Management Instructor: Elizabeth A. Babcock Division of Marine. Introductory Statistics with R. 2nd Edition. Springer. Course Description: This course is intended for students in the life sciences and environmental sciences who have never taken a statistics class, and who

  14. arXiv:physics/0010039 Maximally Informative Statistics

    E-Print Network [OSTI]

    Wolf, David R.

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