Sample records for nems model involves

  1. National Energy Modeling System (NEMS)

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    The National Energy Modeling System (NEMS) is a computer-based, energy-economy modeling system of U.S. through 2030. NEMS projects the production, imports, conversion, consumption, and prices of energy, subject to assumptions on macroeconomic and financial factors, world energy markets, resource availability and costs, behavioral and technological choice criteria, cost and performance characteristics of energy technologies, and demographics. NEMS was designed and implemented by the Energy Information Administration (EIA) of the U.S. Department of Energy (DOE). NEMS can be used to analyze the effects of existing and proposed government laws and regulations related to energy production and use; the potential impact of new and advanced energy production, conversion, and consumption technologies; the impact and cost of greenhouse gas control; the impact of increased use of renewable energy sources; and the potential savings from increased efficiency of energy use; and the impact of regulations on the use of alternative or reformulated fuels. NEMS has also been used for a number of special analyses at the request of the Administration, U.S. Congress, other offices of DOE and other government agencies, who specify the scenarios and assumptions for the analysis. Modules allow analyses to be conducted in energy topic areas such as residential demand, industrial demand, electricity market, oil and gas supply, renewable fuels, etc.

  2. How to obtain the National Energy Modeling System (NEMS)

    Reports and Publications (EIA)

    2013-01-01T23:59:59.000Z

    The National Energy Modeling System (NEMS) NEMS is used by the modelers at the U. S. Energy Information Administration (EIA) who understand its structure and programming. NEMS has only been used by a few organizations outside of the EIA, because most people that requested NEMS found out that it was too difficult or rigid to use. NEMS is not typically used for state-level analysis and is poorly suited for application to other countries. However, many do obtain the model simply to use the data in its input files or to examine the source code.

  3. Price Responsiveness in the AEO2003 NEMS Residential and Commercial Buildings Sector Models

    Reports and Publications (EIA)

    2003-01-01T23:59:59.000Z

    This paper describes the demand responses to changes in energy prices in the Annual Energy Outlook 2003 versions of the Residential and Commercial Demand Modules of the National Energy Modeling System (NEMS). It updates a similar paper completed for the Annual Energy Outlook 1999 version of the NEMS.

  4. National Energy Modeling System (NEMS) | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directedAnnual SiteofEvaluatingGroup |JilinLuOpen Energy Information National AllianceDayNEMS) Jump to:

  5. Learning and cost reductions for generating technologies in the national energy modeling system (NEMS)

    SciTech Connect (OSTI)

    Gumerman, Etan; Marnay, Chris

    2004-01-16T23:59:59.000Z

    This report describes how Learning-by-Doing (LBD) is implemented endogenously in the National Energy Modeling System (NEMS) for generating plants. LBD is experiential learning that correlates to a generating technology's capacity growth. The annual amount of Learning-by-Doing affects the annual overnight cost reduction. Currently, there is no straightforward way to integrate and make sense of all the diffuse information related to the endogenous learning calculation in NEMS. This paper organizes the relevant information from the NEMS documentation, source code, input files, and output files, in order to make the model's logic more accessible. The end results are shown in three ways: in a simple spreadsheet containing all the parameters related to endogenous learning; by an algorithm that traces how the parameters lead to cost reductions; and by examples showing how AEO 2004 forecasts the reduction of overnight costs for generating technologies over time.

  6. NEMS industrial module documentation report

    SciTech Connect (OSTI)

    Not Available

    1994-01-01T23:59:59.000Z

    The NEMS Industrial Demand Model is a dynamic accounting model, bringing together the disparate industries and uses of energy in those industries, and putting them together in an understandable and cohesive framework. The Industrial Model generates mid-term (up to the year 2010) forecasts of industrial sector energy demand as a component of the NEMS integrated forecasting system. From the NEMS system, the Industrial Model receives fuel prices, employment data, and the value of output of industrial activity. Based on the values of these variables, the Industrial Model passes back to the NEMS system estimates of consumption by fuel types.

  7. Net Energy Metering (NEM)

    Broader source: Energy.gov (indexed) [DOE]

    the Arizona Public Service Co. (APS) request for a charge on future rooftop solar panel installations connected to the grid under the state's net energy metering (NEM)...

  8. NEMS integrating module documentation report

    SciTech Connect (OSTI)

    Not Available

    1993-12-14T23:59:59.000Z

    The National Energy Modeling System (NEMS) is a computer modeling system that produces a general equilibrium solution for energy supply and demand in the US energy markets. The model achieves a supply and demand balance in the end-use demand regions, defined as the nine Census Divisions, by solving for the prices of each energy type such that the quantities producers are willing to supply equal the quantities consumers wish to consume. The system reflects market economics, industry structure, and energy policies and regulations that influence market behavior. The NEMS Integrating Module is the central integrating component of a complex modeling system. As such, a thorough understanding of its role in the modeling process can only be achieved by placing it in the proper context with respect to the other modules. To that end, this document provides an overview of the complete NEMS model, and includes brief descriptions of the modules with which the Integrating Module interacts. The emphasis and focus, however, is on the structure and function of the Integrating Module of NEMS.

  9. Assessment and Suggestions to Improve the Commercial Building Module of EIA-NEMS

    E-Print Network [OSTI]

    O'Neal, D. L.; Reddy, T. A.; Sucher, B.

    1996-01-01T23:59:59.000Z

    The National Energy Modeling System (NEMS) is a comprehensive, computer-based, energy-economy modeling system developed and maintained by the Department of Energy's Energy Information Administration (EIA). NEMS forecasts the national production...

  10. U.S. Regional Demand Forecasts Using NEMS and GIS

    SciTech Connect (OSTI)

    Cohen, Jesse A.; Edwards, Jennifer L.; Marnay, Chris

    2005-07-01T23:59:59.000Z

    The National Energy Modeling System (NEMS) is a multi-sector, integrated model of the U.S. energy system put out by the Department of Energy's Energy Information Administration. NEMS is used to produce the annual 20-year forecast of U.S. energy use aggregated to the nine-region census division level. The research objective was to disaggregate this regional energy forecast to the county level for select forecast years, for use in a more detailed and accurate regional analysis of energy usage across the U.S. The process of disaggregation using a geographic information system (GIS) was researched and a model was created utilizing available population forecasts and climate zone data. The model's primary purpose was to generate an energy demand forecast with greater spatial resolution than what is currently produced by NEMS, and to produce a flexible model that can be used repeatedly as an add-on to NEMS in which detailed analysis can be executed exogenously with results fed back into the NEMS data flow. The methods developed were then applied to the study data to obtain residential and commercial electricity demand forecasts. The model was subjected to comparative and statistical testing to assess predictive accuracy. Forecasts using this model were robust and accurate in slow-growing, temperate regions such as the Midwest and Mountain regions. Interestingly, however, the model performed with less accuracy in the Pacific and Northwest regions of the country where population growth was more active. In the future more refined methods will be necessary to improve the accuracy of these forecasts. The disaggregation method was written into a flexible tool within the ArcGIS environment which enables the user to output the results in five year intervals over the period 2000-2025. In addition, the outputs of this tool were used to develop a time-series simulation showing the temporal changes in electricity forecasts in terms of absolute, per capita, and density of demand.

  11. Investigation of residential central air conditioning load shapes in NEMS

    SciTech Connect (OSTI)

    Hamachi LaCommare, Kristina; Marnay, Chris; Gumerman, Etan; Chan, Peter; Rosenquist, Greg; Osborn, Julie

    2002-05-01T23:59:59.000Z

    This memo explains what Berkeley Lab has learned about how the residential central air-conditioning (CAC) end use is represented in the National Energy Modeling System (NEMS). NEMS is an energy model maintained by the Energy Information Administration (EIA) that is routinely used in analysis of energy efficiency standards for residential appliances. As part of analyzing utility and environmental impacts related to the federal rulemaking for residential CAC, lower-than-expected peak utility results prompted Berkeley Lab to investigate the input load shapes that characterize the peaky CAC end use and the submodule that treats load demand response. Investigations enabled a through understanding of the methodology by which hourly load profiles are input to the model and how the model is structured to respond to peak demand. Notably, it was discovered that NEMS was using an October-peaking load shape to represent residential space cooling, which suppressed peak effects to levels lower than expected. An apparent scaling down of the annual load within the load-demand submodule was found, another significant suppressor of the peak impacts. EIA promptly responded to Berkeley Lab's discoveries by updating numerous load shapes for the AEO2002 version of NEMS; EIA is still studying the scaling issue. As a result of this work, it was concluded that Berkeley Lab's customary end-use decrement approach was the most defensible way for Berkeley Lab to perform the recent CAC utility impact analysis. This approach was applied in conjunction with the updated AEO2002 load shapes to perform last year's published rulemaking analysis. Berkeley Lab experimented with several alternative approaches, including modifying the CAC efficiency level, but determined that these did not sufficiently improve the robustness of the method or results to warrant their implementation. Work in this area will continue in preparation for upcoming rulemakings for the other peak coincident end uses, commercial air conditioning and distribution transformers.

  12. Comparison of Bottom-Up and Top-Down Forecasts: Vision Industry Energy Forecasts with ITEMS and NEMS

    E-Print Network [OSTI]

    Roop, J. M.; Dahowski, R. T

    Comparisons are made of energy forecasts using results from the Industrial module of the National Energy Modeling System (NEMS) and an industrial economic-engineering model called the Industrial Technology and Energy Modeling System (ITEMS), a model...

  13. NEMS Buildings Sector Working Group Meeting

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for On-Highway4,1,50022,3,,,,6,1,9,1,50022,3,,,,6,1,Decade1 Source: Office of FossilFoot) Year JanCubicXIV.Mr.NEMS Buildings

  14. Investigation of the effects of soluble boron tracking on coupled CTF / NEM, LWR simulations

    SciTech Connect (OSTI)

    Biery, M.; Avramova, M.; Ivanov, K. [Pennsylvania State University, Department of Mechanical and Nuclear Engineering, 331 Reber Building, University Park, PA 16802 (United States)

    2013-07-01T23:59:59.000Z

    The primary objective of this study is to evaluate the effects of introducing a boron tracking capability to the COBRA-TF / NEM code coupling. The Pennsylvania State University (PSU) versions of COBRA-TF - CTF, and Nodal Expansion Method (NEM) codes are utilized. Previous implementations of the CTF / NEM coupled code had no capability to model soluble boron feedback effects due to boron transport. This study builds upon the validation and qualification efforts of the boron tracking model implementation in CTF by modeling the boron feedback calculated by the CTF boron tracking model in NEM. The core model chosen for this study is the Purdue MOX/UO{sub 2} core model used in the 2007 OECD/NRC code benchmark study. Following the implementation of an explicit online coupling scheme and accompanying k-search routine, the newly coupled CTF / NEM code version with boron tracking is compared to prior results of the non-boron tracking CTF / NEM code version at steady-state hot full power and hot zero power conditions. It was found that the boron tracking model exhibited little influence on the hot zero power result as expected due to a smaller heat flux, which does not significantly change the moderator density and boron concentration as the moderator travels up the axial core length. Meanwhile the boron tracking model had a much greater impact on the hot full power results, predicting the critical inlet boron concentration to be 9.9 ppm below the non-boron tracking result due to greater and more rapid changes in boron concentration corresponding to the reduction in moderator density from being more rapidly heated. (authors)

  15. Overview of NEMS-H2, Version 1.0

    Broader source: Energy.gov [DOE]

    Presentation on Overview of NEMS-H2, Version 1.0 given by Frances Wood of OnLocation during the DOE Hydrogen Transition Analysis Workshop on January 26, 2006.

  16. A sensitivity analysis of the treatment of wind energy in the AEO99 version of NEMS

    SciTech Connect (OSTI)

    Osborn, Julie G; Wood, Frances; Richey, Cooper; Sanders, Sandy; Short, Walter; Koomey, Jonathan

    2001-01-01T23:59:59.000Z

    Each year, the U.S. Department of Energy's Energy Information Administration (EIA) publishes a forecast of the domestic energy economy in the Annual Energy Outlook (AEO). During the forecast period of the AEO (currently through 2020), renewable energy technologies have typically not achieved significant growth. The contribution of renewable technologies as electric generators becomes more important, however, in scenarios analyzing greenhouse gas emissions reductions or significant technological advancements. We examined the economic assumptions about wind power used for producing forecasts with the National Energy Modeling System (NEMS) to determine their influence on the projected capacity expansion of this technology. This analysis should help illustrate to policymakers what types of issues may affect wind development, and improve the general understanding of the NEMS model itself. Figure 1 illustrates the model structure and factors relevant to wind deployment. We found that NEMS uses various cost multipliers and constraints to represent potential physical and economic limitations to growth in wind capacity, such as resource depletion, costs associated with rapid manufacturing expansion, and grid stability with high levels of capacity from intermittent resources. The model's flexibility allows the user to make alternative assumptions about the magnitude of these factors. While these assumptions have little effect on the Reference Case forecast for the 1999 edition of the AEO, they can make a dramatic difference when wind is more attractive, such as under a carbon permit trading system. With $100/ton carbon permits, the wind capacity projection for 2020 ranges from 15 GW in the unaltered model (AEO99 Reference Case) to 168 GW in the extreme case when all the multipliers and constraints examined in this study are removed. Furthermore, if modifications are made to the model allowing inter-regional transmission of electricity, wind capacity is forecast to reach 214 GW when all limitations are removed. The figures in the upper end of these ranges are not intended to be viewed as reasonable projections, but their magnitude illustrates the importance of the parameters governing the growth of wind capacity and resource availability in forecasts using NEMS. In addition, many uncertainties exist regarding these assumptions that potentially affect the growth of wind power. We suggest several areas in which to focus future research in order to better model the potential development of this resource. Because many of the assumptions related to wind in the model are also used for other renewable technologies, these suggestions could be applied to other renewable resources as well.

  17. Appendix E: Other NEMS-MP results for the base case and scenarios.

    SciTech Connect (OSTI)

    Plotkin, S. E.; Singh, M. K.; Energy Systems

    2009-12-03T23:59:59.000Z

    The NEMS-MP model generates numerous results for each run of a scenario. (This model is the integrated National Energy Modeling System [NEMS] version used for the Multi-Path Transportation Futures Study [MP].) This appendix examines additional findings beyond the primary results reported in the Multi-Path Transportation Futures Study: Vehicle Characterization and Scenario Analyses (Reference 1). These additional results are provided in order to help further illuminate some of the primary results. Specifically discussed in this appendix are: (1) Energy use results for light vehicles (LVs), including details about the underlying total vehicle miles traveled (VMT), the average vehicle fuel economy, and the volumes of the different fuels used; (2) Resource fuels and their use in the production of ethanol, hydrogen (H{sub 2}), and electricity; (3) Ethanol use in the scenarios (i.e., the ethanol consumption in E85 vs. other blends, the percent of travel by flex fuel vehicles on E85, etc.); (4) Relative availability of E85 and H2 stations; (5) Fuel prices; (6) Vehicle prices; and (7) Consumer savings. These results are discussed as follows: (1) The three scenarios (Mixed, (P)HEV & Ethanol, and H2 Success) when assuming vehicle prices developed through literature review; (2) The three scenarios with vehicle prices that incorporate the achievement of the U.S. Department of Energy (DOE) program vehicle cost goals; (3) The three scenarios with 'literature review' vehicle prices, plus vehicle subsidies; and (4) The three scenarios with 'program goals' vehicle prices, plus vehicle subsidies. The four versions or cases of each scenario are referred to as: Literature Review No Subsidies, Program Goals No Subsidies, Literature Review with Subsidies, and Program Goals with Subsidies. Two additional points must be made here. First, none of the results presented for LVs in this section include Class 2B trucks. Results for this class are included occasionally in Reference 1. They represent a small, though noticeable, segment of the 'LV plus 2B' market (e.g., a little more than 3% of today's energy use in that market). We generally do not include them in this discussion, simply because it requires additional effort to combine the NEMS-MP results for them with the results for the other LVs. (Where there is an exception, we will indicate so.) Second, where reference is made to E85, the ethanol content is actually 74%. The Energy Information Administration (EIA) assumes that, to address cold-starting issues, the percent of ethanol in E85 will vary seasonally. The EIA uses an annual average ethanol content of 74% in its forecasts. That assumption is maintained in the NEMS-MP scenario runs.

  18. Nano-Electro-Mechanical (NEM) Relay Devices and Technology for Ultra-Low Energy Digital Integrated Circuits

    E-Print Network [OSTI]

    Nathanael, Rhesa

    2012-01-01T23:59:59.000Z

    Technology 3.1 Introduction Nano-electro-mechanical (NEM)improvements, a scaled nano-relay technology with optimizedNano-Electro-Mechanical (NEM) Relay Devices and Technology

  19. A sensitivity analysis of the treatment of wind energy in the AEO99 version of NEMS

    E-Print Network [OSTI]

    Osborn, Julie G.; Wood, Frances; Richey, Cooper; Sanders, Sandy; Short, Walter; Koomey, Jonathan

    2001-01-01T23:59:59.000Z

    Documentation Report: Wind Energy Submodule (WES). DOE/EIA-The Economic Value of Wind Energy at High Power SystemOF THE TREATMENT OF WIND ENERGY IN THE AEO99 VERSION OF NEMS

  20. Recycling Guide: Reduce, Reuse, Recycle Recycling Information Call 301-496-7990 or visit the NEMS Website at http://www.nems.nih.gov

    E-Print Network [OSTI]

    Baker, Chris I.

    Recycling Guide: Reduce, Reuse, Recycle Recycling Information ­ Call 301-496-7990 or visit the NEMS in COMMINGLED bin Rinse food/beverage containers before recycling No Pyrex or Styrofoam Printer and Copier Toner Cartridges in TONER CARTRIDGE bin Recycle packaging material in appropriate bin NIH charities

  1. Overview of NEMS-H2, Version 1.0 Frances Wood

    E-Print Network [OSTI]

    ConsumptionForm/Place Transformations Electricity Generation and Transmission Hydrogen Oil and Gas ProductionOverview of NEMS-H2, Version 1.0 Frances Wood OnLocation, Inc., Energy Systems Consulting (fwood markets ­ Focus is on economic, not engineering, aspects of hydrogen production, delivery, and consumption

  2. H Loop shaping control for PLL-based mechanical resonance tracking in NEMS resonant mass sensors

    E-Print Network [OSTI]

    Boyer, Edmond

    problem that rejects the disturbance described by the resonance frequency shift, attenuates the phase the measurement scheme to a disturbance rejection control issue which considers the resonance frequency variation--A simple dynamic detection of the resonance frequency shift in NEMS resonant mass sensors is described

  3. A SENSITIVITY ANALYSIS OF THE TREATMENT OF WIND ENERGY IN THE AEO99 VERSION OF NEMS

    E-Print Network [OSTI]

    LBNL-44070 TP-28529 A SENSITIVITY ANALYSIS OF THE TREATMENT OF WIND ENERGY IN THE AEO99 VERSION Analysis Department Environmental Energy Technologies Division Ernest Orlando Lawrence Berkeley National OF NEMS Julie Osborn, Frances Wood, Cooper Richey, Sandy Sanders, Walter Short, and Jonathan Koomey Energy

  4. Directory of Energy Information Administration Models 1993

    SciTech Connect (OSTI)

    Not Available

    1993-07-06T23:59:59.000Z

    This directory contains descriptions about each model, including the title, acronym, purpose, followed by more detailed information on characteristics, uses, and requirements. Sources for additional information are identified. Included in this directory are 35 EIA models active as of May 1, 1993. Models that run on personal computers are identified by ``PC`` as part of the acronym. EIA is developing new models, a National Energy Modeling System (NEMS), and is making changes to existing models to include new technologies, environmental issues, conservation, and renewables, as well as extend forecast horizon. Other parts of the Department are involved in this modeling effort. A fully operational model is planned which will integrate completed segments of NEMS for its first official application--preparation of EIA`s Annual Energy Outlook 1994. Abstracts for the new models will be included in next year`s version of this directory.

  5. Adaptive Density Estimation in the Pile-up Model Involving Measurement Errors

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Adaptive Density Estimation in the Pile-up Model Involving Measurement Errors Fabienne Comte, Tabea of nonparametric density estimation in the pile-up model. Adaptive nonparametric estimators are proposed for the pile-up model in its simple form as well as in the case of additional measurement errors. Furthermore

  6. National Energy Modeling System with Hydrogen Model (NEMS-H2)

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onYouTube YouTube Note: Since the.pdfBreaking ofOilNEW HAMPSHIRE BUILDS OFFNanolens WindowDepartmentRFI |Energy

  7. Pore scale modeling of reactive transport involved in geologic CO2 sequestration

    SciTech Connect (OSTI)

    Kang, Qinjin [Los Alamos National Laboratory; Lichtner, Peter C [Los Alamos National Laboratory; Viswanathan, Hari S [Los Alamos National Laboratory; Abdel-fattah, Amr I [Los Alamos National Laboratory

    2009-01-01T23:59:59.000Z

    We apply a multi-component reactive transport lattice Boltzmann model developed in previolls studies to modeling the injection of a C02 saturated brine into various porous media structures at temperature T=25 and 80 C. The porous media are originally consisted of calcite. A chemical system consisting of Na+, Ca2+, Mg2+, H+, CO2(aq), and CI-is considered. The fluid flow, advection and diHusion of aqueous species, homogeneous reactions occurring in the bulk fluid, as weB as the dissolution of calcite and precipitation of dolomite are simulated at the pore scale. The effects of porous media structure on reactive transport are investigated. The results are compared with continuum scale modeling and the agreement and discrepancy are discussed. This work may shed some light on the fundamental physics occurring at the pore scale for reactive transport involved in geologic C02 sequestration.

  8. Mechanochemical modeling of dynamic microtubule growth involving sheet-to-tube transition

    E-Print Network [OSTI]

    Xiang-Ying Ji; Xi-Qiao Feng

    2011-08-02T23:59:59.000Z

    Microtubule dynamics is largely influenced by nucleotide hydrolysis and the resultant tubulin configuration changes. The GTP cap model has been proposed to interpret the stabilizing mechanism of microtubule growth from the view of hydrolysis effects. Besides, the microtubule growth involves the closure of a curved sheet at its growing end. The curvature conversion also helps to stabilize the successive growth, and the curved sheet is referred to as the conformational cap. However, there still lacks theoretical investigation on the mechanical-chemical coupling growth process of microtubules. In this paper, we study the growth mechanisms of microtubules by using a coarse-grained molecular method. Firstly, the closure process involving a sheet-to-tube transition is simulated. The results verify the stabilizing effect of the sheet structure, and the minimum conformational cap length that can stabilize the growth is demonstrated to be two dimers. Then, we show that the conformational cap can function independently of the GTP cap, signifying the pivotal role of mechanical factors. Furthermore, based on our theoretical results, we describe a Tetris-like growth style of microtubules: the stochastic tubulin assembly is regulated by energy and harmonized with the seam zipping such that the sheet keeps a practically constant length during growth.

  9. Learning and cost reductions for generating technologies in the national energy modeling system (NEMS)

    E-Print Network [OSTI]

    Gumerman, Etan; Marnay, Chris

    2004-01-01T23:59:59.000Z

    Assumptions to the Annual Energy Outlook 2001. Report#:DOE/ENDOGENOUS LEARNING IN THE ANNUAL ENERGY OUTLOOK REFERENCEDepartment of Energy’s Annual Energy Outlook (AEO), which is

  10. Learning and cost reductions for generating technologies in the national energy modeling system (NEMS)

    E-Print Network [OSTI]

    Gumerman, Etan; Marnay, Chris

    2004-01-01T23:59:59.000Z

    of International Learning on Technology Cost. In Issues ofbetween initial new technology cost estimates and actualthe revolutionary technologies have cost reductions beyond

  11. A sensitivity analysis of the treatment of wind energy in the AEO99 version of NEMS

    E-Print Network [OSTI]

    Osborn, Julie G.; Wood, Frances; Richey, Cooper; Sanders, Sandy; Short, Walter; Koomey, Jonathan

    2001-01-01T23:59:59.000Z

    Energy Information Administration (EIA) National Energy Modeling System (Energy Information Administration’s (EIA) National Energy Modeling System (

  12. A sensitivity analysis of the treatment of wind energy in the AEO99 version of NEMS

    E-Print Network [OSTI]

    Osborn, Julie G.; Wood, Frances; Richey, Cooper; Sanders, Sandy; Short, Walter; Koomey, Jonathan

    2001-01-01T23:59:59.000Z

    Documentation Report: Wind Energy Submodule (WES). DOE/EIA-The Economic Value of Wind Energy at High Power Systemthe characterization of wind energy in the model as used for

  13. Optical model potentials involving loosely bound p-shell nuclei around 10 MeV/nucleon 

    E-Print Network [OSTI]

    Trache, L.; Azhari, A.; Clark, HL; Gagliardi, Carl A.; Lui, YW; Mukhamedzhanov, AM; Tribble, Robert E.; Carstoiu, F.

    2000-01-01T23:59:59.000Z

    model with real effective interactions the absorption is accounted for phenomenologically by adding an imaginary potential of the same shape as the real part U~r !5~NV1iNW!V fold~r !, ~15! whereas for the cases when the effective interaction also... reanalyzed all our elastic scattering data using double folding potentials obtained with the six effective interactions outlined above. The renormalization constants NV and NW were further adjusted to fit the elastic scattering data using Eq. ~15...

  14. Natural gas transmission and distribution model of the National Energy Modeling System

    SciTech Connect (OSTI)

    NONE

    1997-02-01T23:59:59.000Z

    The Natural Gas Transmission and Distribution Model (NGTDM) is the component of the National Energy Modeling System (NEMS) that is used to represent the domestic natural gas transmission and distribution system. NEMS was developed in the Office of Integrated Analysis and Forecasting of the Energy Information Administration (EIA). NEMS is the third in a series of computer-based, midterm energy modeling systems used since 1974 by the EIA and its predecessor, the Federal Energy Administration, to analyze domestic energy-economy markets and develop projections. From 1982 through 1993, the Intermediate Future Forecasting System (IFFS) was used by the EIA for its analyses, and the Gas Analysis Modeling System (GAMS) was used within IFFS to represent natural gas markets. Prior to 1982, the Midterm Energy Forecasting System (MEFS), also referred to as the Project Independence Evaluation System (PIES), was employed. NEMS was developed to enhance and update EIA`s modeling capability by internally incorporating models of energy markets that had previously been analyzed off-line. In addition, greater structural detail in NEMS permits the analysis of a broader range of energy issues. The time horizon of NEMS is the midterm period (i.e., through 2015). In order to represent the regional differences in energy markets, the component models of NEMS function at regional levels appropriate for the markets represented, with subsequent aggregation/disaggregation to the Census Division level for reporting purposes.

  15. Genome-Wide Identification and 3D Modeling of Proteins involved in DNA Damage Recognition and Repair (Final Report)

    SciTech Connect (OSTI)

    Ruben A. Abagyan, PhD

    2004-04-15T23:59:59.000Z

    OAK-B135 DNA Damage Recognition and Repair (DDR and R) proteins play a critical role in cellular responses to low-dose radiation and are associated with cancer. the authors have performed a systematic, genome-wide computational analysis of genomic data for human genes involved in the DDR and R process. The significant achievements of this project include: (1) Construction of the computational pipeline for searching DDR and R genes, building and validation of 3D models of proteins involved in DDR and R; (2) Functional and structural annotation of the 3D models and generation of comprehensive lists of suggested knock-out mutations; (3) Important improvement of macromolecular docking technology and its application to predict the DNA-Protein complex conformation; (4) Development of a new algorithm for improved analysis of high-density oligonucleotide arrays for gene expression profiling; (5) Construction and maintenance of the DNA Damage Recognition and Repair Database; and (6) Producing 14 research papers (10 published and 4 in preparation).

  16. Model documentation report: Industrial sector demand module of the National Energy Modeling System

    SciTech Connect (OSTI)

    NONE

    1997-01-01T23:59:59.000Z

    This report documents the objectives, analytical approach, and development of the National Energy Modeling System (NEMS) Industrial Demand Model. The report catalogues and describes model assumptions, computational methodology, parameter estimation techniques, and model source code. This document serves three purposes. First, it is a reference document providing a detailed description of the NEMS Industrial Model for model analysts, users, and the public. Second, this report meets the legal requirement of the Energy Information Administration (EIA) to provide adequate documentation in support of its models. Third, it facilitates continuity in model development by providing documentation from which energy analysts can undertake model enhancements, data updates, and parameter refinements as future projects. The NEMS Industrial Demand Model is a dynamic accounting model, bringing together the disparate industries and uses of energy in those industries, and putting them together in an understandable and cohesive framework. The Industrial Model generates mid-term (up to the year 2015) forecasts of industrial sector energy demand as a component of the NEMS integrated forecasting system. From the NEMS system, the Industrial Model receives fuel prices, employment data, and the value of industrial output. Based on the values of these variables, the Industrial Model passes back to the NEMS system estimates of consumption by fuel types.

  17. Parent Involvement

    E-Print Network [OSTI]

    Howard, Jeff W.

    2005-05-10T23:59:59.000Z

    To be successful, a 4-H program must have parent involvement. Although 4-H leaders and Extension agents may interest young people in becoming members, they need the parents' goodwill and support to keep them interested, enthusiastic and active. Here...

  18. Greenhouse Gas Initiatives - Analysis of McCain-Lieberman Bill S.280 ‘The ClimateStewardship and Innovation Act of 2007’ Using the National Energy Modeling System

    E-Print Network [OSTI]

    Ellsworth, C.

    2008-01-01T23:59:59.000Z

    , and prices, and the technologies and market mechanisms that are likely to be employed to reduce CO2 emissions. The paper also reports on the results of analysis of GHG bills performed by SAIC using the National Energy Modeling System (NEMS). NEMS...

  19. Greenhouse Gas Initiatives - Analysis of McCain-Lieberman Bill S.280 ‘The ClimateStewardship and Innovation Act of 2007’ Using the National Energy Modeling System 

    E-Print Network [OSTI]

    Ellsworth, C.

    2008-01-01T23:59:59.000Z

    , and prices, and the technologies and market mechanisms that are likely to be employed to reduce CO2 emissions. The paper also reports on the results of analysis of GHG bills performed by SAIC using the National Energy Modeling System (NEMS). NEMS...

  20. The National Energy Modeling System: An overview 1998

    SciTech Connect (OSTI)

    NONE

    1998-02-01T23:59:59.000Z

    The National Energy Modeling System (NEMS) is a computer-based, energy-economy modeling system of US energy markets for the midterm period through 2020. NEMS projects the production, imports, conversion, consumption, and prices of energy, subject to assumptions on macroeconomic and financial factors world energy markets, resource availability and costs, behavior and technological choice criteria, cost and performance characteristics of energy technologies, and demographics. This report presents an overview of the structure and methodology of NEMS and each of its components. The first chapter provides a description of the design and objectives of the system, followed by a chapter on the overall modeling structure and solution algorithm. The remainder of the report summarizes the methodology and scope of the component modules of NEMS. The model descriptions are intended for readers familiar with terminology from economics, operations research, and energy modeling. 21 figs.

  1. Model documentation report: Industrial sector demand module of the national energy modeling system

    SciTech Connect (OSTI)

    NONE

    1998-01-01T23:59:59.000Z

    This report documents the objectives, analytical approach, and development of the National Energy Modeling System (NEMS) Industrial Demand Model. The report catalogues and describes model assumptions, computational methodology, parameter estimation techniques, and model source code. This document serves three purposes. First, it is a reference document providing a detailed description of the NEMS Industrial Model for model analysts, users, and the public. Second, this report meets the legal requirements of the Energy Information Administration (EIA) to provide adequate documentation in support of its model. Third, it facilitates continuity in model development by providing documentation from which energy analysts can undertake model enhancements, data updates, and parameter refinements as future projects.

  2. Impacts of Modeled Recommendations of the National Commission on Energy Policy

    Reports and Publications (EIA)

    2005-01-01T23:59:59.000Z

    This report provides the Energy Information Administration's analysis of those National Commission on Energy Policy (NCEP) energy policy recommendations that could be simulated using the National Energy Modeling System (NEMS).

  3. Prozodi?ne možnosti v slovenskem knjižnem jeziku in slovenskih nare?jih

    E-Print Network [OSTI]

    Greenberg, Marc L.

    1987-01-01T23:59:59.000Z

    Following a mathematical model devised by Pavle Ivi?, the author provides an overview of functional load of suprasegmental contrasts in the strikingly variegated dialect systems of Slovene.

  4. Model documentation Renewable Fuels Module of the National Energy Modeling System

    SciTech Connect (OSTI)

    NONE

    1996-01-01T23:59:59.000Z

    This report documents the objectives, analaytical approach and design of the National Energy Modeling System (NEMS) Renewable Fuels Module (RFM) as it relates to the production of the 1996 Annual Energy Outlook forecasts. The report catalogues and describes modeling assumptions, computational methodologies, data inputs, and parameter estimation techniques. A number of offline analyses used in lieu of RFM modeling components are also described.

  5. Model documentation, Coal Market Module of the National Energy Modeling System

    SciTech Connect (OSTI)

    NONE

    1998-01-01T23:59:59.000Z

    This report documents the objectives and the conceptual and methodological approach used in the development of the National Energy Modeling System`s (NEMS) Coal Market Module (CMM) used to develop the Annual Energy Outlook 1998 (AEO98). This report catalogues and describes the assumptions, methodology, estimation techniques, and source code of CMM`s two submodules. These are the Coal Production Submodule (CPS) and the Coal Distribution Submodule (CDS). CMM provides annual forecasts of prices, production, and consumption of coal for NEMS. In general, the CDS integrates the supply inputs from the CPS to satisfy demands for coal from exogenous demand models. The international area of the CDS forecasts annual world coal trade flows from major supply to major demand regions and provides annual forecasts of US coal exports for input to NEMS. Specifically, the CDS receives minemouth prices produced by the CPS, demand and other exogenous inputs from other NEMS components, and provides delivered coal prices and quantities to the NEMS economic sectors and regions.

  6. Model documentation: Natural gas transmission and distribution model of the National Energy Modeling System. Volume 1

    SciTech Connect (OSTI)

    NONE

    1995-02-17T23:59:59.000Z

    The Natural Gas Transmission and Distribution Model (NGTDM) is the component of the National Energy Modeling System (NEMS) that is used to represent the domestic natural gas transmission and distribution system. NEMS was developed in the Office of integrated Analysis and Forecasting of the Energy information Administration (EIA). NEMS is the third in a series of computer-based, midterm energy modeling systems used since 1974 by the EIA and its predecessor, the Federal Energy Administration, to analyze domestic energy-economy markets and develop projections. The NGTDM is the model within the NEMS that represents the transmission, distribution, and pricing of natural gas. The model also includes representations of the end-use demand for natural gas, the production of domestic natural gas, and the availability of natural gas traded on the international market based on information received from other NEMS models. The NGTDM determines the flow of natural gas in an aggregate, domestic pipeline network, connecting domestic and foreign supply regions with 12 demand regions. The methodology employed allows the analysis of impacts of regional capacity constraints in the interstate natural gas pipeline network and the identification of pipeline capacity expansion requirements. There is an explicit representation of core and noncore markets for natural gas transmission and distribution services, and the key components of pipeline tariffs are represented in a pricing algorithm. Natural gas pricing and flow patterns are derived by obtaining a market equilibrium across the three main elements of the natural gas market: the supply element, the demand element, and the transmission and distribution network that links them. The NGTDM consists of four modules: the Annual Flow Module, the Capacity F-expansion Module, the Pipeline Tariff Module, and the Distributor Tariff Module. A model abstract is provided in Appendix A.

  7. Natural Gas Transmission and Distribution Model of the National Energy Modeling System. Volume 1

    SciTech Connect (OSTI)

    NONE

    1998-01-01T23:59:59.000Z

    The Natural Gas Transmission and Distribution Model (NGTDM) is the component of the National Energy Modeling System (NEMS) that is used to represent the domestic natural gas transmission and distribution system. The NGTDM is the model within the NEMS that represents the transmission, distribution, and pricing of natural gas. The model also includes representations of the end-use demand for natural gas, the production of domestic natural gas, and the availability of natural gas traded on the international market based on information received from other NEMS models. The NGTDM determines the flow of natural gas in an aggregate, domestic pipeline network, connecting domestic and foreign supply regions with 12 demand regions. The purpose of this report is to provide a reference document for model analysts, users, and the public that defines the objectives of the model, describes its basic design, provides detail on the methodology employed, and describes the model inputs, outputs, and key assumptions. Subsequent chapters of this report provide: an overview of NGTDM; a description of the interface between the NEMS and NGTDM; an overview of the solution methodology of the NGTDM; the solution methodology for the Annual Flow Module; the solution methodology for the Distributor Tariff Module; the solution methodology for the Capacity Expansion Module; the solution methodology for the Pipeline Tariff Module; and a description of model assumptions, inputs, and outputs.

  8. Understanding Energy Models and Modeling (ENV 715) Spring 2013 Tuesday/Thursday 10:05-11:20 am

    E-Print Network [OSTI]

    Ferrari, Silvia

    topics for Congress, and publishes the Annual Energy Outlook. At Duke, NI-NEMS has recently been used1 Understanding Energy Models and Modeling (ENV 715) Spring 2013 Tuesday/Thursday 10:05-11:20 am) Course Description and Learning Objectives Energy models are widely used for policy analysis, scenario

  9. Distributed generation capabilities of the national energy modeling system

    SciTech Connect (OSTI)

    LaCommare, Kristina Hamachi; Edwards, Jennifer L.; Marnay, Chris

    2003-01-01T23:59:59.000Z

    This report describes Berkeley Lab's exploration of how the National Energy Modeling System (NEMS) models distributed generation (DG) and presents possible approaches for improving how DG is modeled. The on-site electric generation capability has been available since the AEO2000 version of NEMS. Berkeley Lab has previously completed research on distributed energy resources (DER) adoption at individual sites and has developed a DER Customer Adoption Model called DER-CAM. Given interest in this area, Berkeley Lab set out to understand how NEMS models small-scale on-site generation to assess how adequately DG is treated in NEMS, and to propose improvements or alternatives. The goal is to determine how well NEMS models the factors influencing DG adoption and to consider alternatives to the current approach. Most small-scale DG adoption takes place in the residential and commercial modules of NEMS. Investment in DG ultimately offsets purchases of electricity, which also eliminates the losses associated with transmission and distribution (T&D). If the DG technology that is chosen is photovoltaics (PV), NEMS assumes renewable energy consumption replaces the energy input to electric generators. If the DG technology is fuel consuming, consumption of fuel in the electric utility sector is replaced by residential or commercial fuel consumption. The waste heat generated from thermal technologies can be used to offset the water heating and space heating energy uses, but there is no thermally activated cooling capability. This study consists of a review of model documentation and a paper by EIA staff, a series of sensitivity runs performed by Berkeley Lab that exercise selected DG parameters in the AEO2002 version of NEMS, and a scoping effort of possible enhancements and alternatives to NEMS current DG capabilities. In general, the treatment of DG in NEMS is rudimentary. The penetration of DG is determined by an economic cash-flow analysis that determines adoption based on the n umber of years to a positive cash flow. Some important technologies, e.g. thermally activated cooling, are absent, and ceilings on DG adoption are determined by some what arbitrary caps on the number of buildings that can adopt DG. These caps are particularly severe for existing buildings, where the maximum penetration for any one technology is 0.25 percent. On the other hand, competition among technologies is not fully considered, and this may result in double-counting for certain applications. A series of sensitivity runs show greater penetration with net metering enhancements and aggressive tax credits and a more limited response to lowered DG technology costs. Discussion of alternatives to the current code is presented in Section 4. Alternatives or improvements to how DG is modeled in NEMS cover three basic areas: expanding on the existing total market for DG both by changing existing parameters in NEMS and by adding new capabilities, such as for missing technologies; enhancing the cash flow analysis but incorporating aspects of DG economics that are not currently represented, e.g. complex tariffs; and using an external geographic information system (GIS) driven analysis that can better and more intuitively identify niche markets.

  10. Directory of energy information administration models 1995

    SciTech Connect (OSTI)

    NONE

    1995-07-13T23:59:59.000Z

    This updated directory has been published annually; after this issue, it will be published only biennially. The Disruption Impact Simulator Model in use by EIA is included. Model descriptions have been updated according to revised documentation approved during the past year. This directory contains descriptions about each model, including title, acronym, purpose, followed by more detailed information on characteristics, uses, and requirements. Sources for additional information are identified. Included are 37 EIA models active as of February 1, 1995. The first group is the National Energy Modeling System (NEMS) models. The second group is all other EIA models that are not part of NEMS. Appendix A identifies major EIA modeling systems and the models within these systems. Appendix B is a summary of the `Annual Energy Outlook` Forecasting System.

  11. Model documentation Coal Market Module of the National Energy Modeling System

    SciTech Connect (OSTI)

    NONE

    1996-04-30T23:59:59.000Z

    This report documents objectives and conceptual and methodological approach used in the development of the National Energy Modeling System (NEMS) Coal Market Module (CMM) used to develop the Annual Energy Outlook 1996 (AEO96). This report catalogues and describes the assumptions, methodology, estimation techniques, and source code of CMM`s three submodules: Coal Production Submodule, Coal Export Submodule, and Coal Distribution Submodule.

  12. Data gathering to build and validate small-scale social models for simulation. Two ways: strict control and stake-holders involvement

    E-Print Network [OSTI]

    Tesfatsion, Leigh

    Data gathering to build and validate small-scale social models for simulation. Two ways: strict.rouchier@univmed.fr Kyoto, 2005 - 10 - 13 Modelling and the search for realism Social simulation using multi-agent paradigm (sometimes called "agent-based simulation" or "simulation with agents") has developed quickly in the last

  13. A Model of U.S. Commercial Distributed Generation Adoption

    SciTech Connect (OSTI)

    LaCommare, Kristina Hamachi; Ryan Firestone; Zhou, Nan; Maribu,Karl; Marnay, Chris

    2006-01-10T23:59:59.000Z

    Small-scale (100 kW-5 MW) on-site distributed generation (DG) economically driven by combined heat and power (CHP) applications and, in some cases, reliability concerns will likely emerge as a common feature of commercial building energy systems over the next two decades. Forecasts of DG adoption published by the Energy Information Administration (EIA) in the Annual Energy Outlook (AEO) are made using the National Energy Modeling System (NEMS), which has a forecasting module that predicts the penetration of several possible commercial building DG technologies over the period 2005-2025. NEMS is also used for estimating the future benefits of Department of Energy research and development used in support of budget requests and management decisionmaking. The NEMS approach to modeling DG has some limitations, including constraints on the amount of DG allowed for retrofits to existing buildings and a small number of possible sizes for each DG technology. An alternative approach called Commercial Sector Model (ComSeM) is developed to improve the way in which DG adoption is modeled. The approach incorporates load shapes for specific end uses in specific building types in specific regions, e.g., cooling in hospitals in Atlanta or space heating in Chicago offices. The Distributed Energy Resources Customer Adoption Model (DER-CAM) uses these load profiles together with input cost and performance DG technology assumptions to model the potential DG adoption for four selected cities and two sizes of five building types in selected forecast years to 2022. The Distributed Energy Resources Market Diffusion Model (DER-MaDiM) is then used to then tailor the DER-CAM results to adoption projections for the entire U.S. commercial sector for all forecast years from 2007-2025. This process is conducted such that the structure of results are consistent with the structure of NEMS, and can be re-injected into NEMS that can then be used to integrate adoption results into a full forecast.

  14. Model documentation report: Commercial Sector Demand Module of the National Energy Modeling System

    SciTech Connect (OSTI)

    NONE

    1998-01-01T23:59:59.000Z

    This report documents the objectives, analytical approach and development of the National Energy Modeling System (NEMS) Commercial Sector Demand Module. The report catalogues and describes the model assumptions, computational methodology, parameter estimation techniques, model source code, and forecast results generated through the synthesis and scenario development based on these components. The NEMS Commercial Sector Demand Module is a simulation tool based upon economic and engineering relationships that models commercial sector energy demands at the nine Census Division level of detail for eleven distinct categories of commercial buildings. Commercial equipment selections are performed for the major fuels of electricity, natural gas, and distillate fuel, for the major services of space heating, space cooling, water heating, ventilation, cooking, refrigeration, and lighting. The algorithm also models demand for the minor fuels of residual oil, liquefied petroleum gas, steam coal, motor gasoline, and kerosene, the renewable fuel sources of wood and municipal solid waste, and the minor services of office equipment. Section 2 of this report discusses the purpose of the model, detailing its objectives, primary input and output quantities, and the relationship of the Commercial Module to the other modules of the NEMS system. Section 3 of the report describes the rationale behind the model design, providing insights into further assumptions utilized in the model development process to this point. Section 3 also reviews alternative commercial sector modeling methodologies drawn from existing literature, providing a comparison to the chosen approach. Section 4 details the model structure, using graphics and text to illustrate model flows and key computations.

  15. Involvement and Communication Committee.

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Science (SC)Integrated Codes | NationalCurriculum IntroductionInvestor andPublic Involvement

  16. Directory of Energy Information Administration Models 1994

    SciTech Connect (OSTI)

    Not Available

    1994-07-01T23:59:59.000Z

    This directory revises and updates the 1993 directory and includes 15 models of the National Energy Modeling System (NEMS). Three other new models in use by the Energy Information Administration (EIA) have also been included: the Motor Gasoline Market Model (MGMM), Distillate Market Model (DMM), and the Propane Market Model (PPMM). This directory contains descriptions about each model, including title, acronym, purpose, followed by more detailed information on characteristics, uses and requirements. Sources for additional information are identified. Included in this directory are 37 EIA models active as of February 1, 1994.

  17. Model documentation: Natural Gas Transmission and Distribution Model of the National Energy Modeling System; Volume 1

    SciTech Connect (OSTI)

    NONE

    1994-02-24T23:59:59.000Z

    The Natural Gas Transmission and Distribution Model (NGTDM) is a component of the National Energy Modeling System (NEMS) used to represent the domestic natural gas transmission and distribution system. NEMS is the third in a series of computer-based, midterm energy modeling systems used since 1974 by the Energy Information Administration (EIA) and its predecessor, the Federal Energy Administration, to analyze domestic energy-economy markets and develop projections. This report documents the archived version of NGTDM that was used to produce the natural gas forecasts used in support of the Annual Energy Outlook 1994, DOE/EIA-0383(94). The purpose of this report is to provide a reference document for model analysts, users, and the public that defines the objectives of the model, describes its basic design, provides detail on the methodology employed, and describes the model inputs, outputs, and key assumptions. It is intended to fulfill the legal obligation of the EIA to provide adequate documentation in support of its models (Public Law 94-385, Section 57.b.2). This report represents Volume 1 of a two-volume set. (Volume 2 will report on model performance, detailing convergence criteria and properties, results of sensitivity testing, comparison of model outputs with the literature and/or other model results, and major unresolved issues.) Subsequent chapters of this report provide: (1) an overview of the NGTDM (Chapter 2); (2) a description of the interface between the National Energy Modeling System (NEMS) and the NGTDM (Chapter 3); (3) an overview of the solution methodology of the NGTDM (Chapter 4); (4) the solution methodology for the Annual Flow Module (Chapter 5); (5) the solution methodology for the Distributor Tariff Module (Chapter 6); (6) the solution methodology for the Capacity Expansion Module (Chapter 7); (7) the solution methodology for the Pipeline Tariff Module (Chapter 8); and (8) a description of model assumptions, inputs, and outputs (Chapter 9).

  18. Model documentation: Renewable Fuels Module of the National Energy Modeling System

    SciTech Connect (OSTI)

    Not Available

    1994-04-01T23:59:59.000Z

    This report documents the objectives, analytical approach, and design of the National Energy Modeling System (NEMS) Renewable Fuels Module (RFM) as it related to the production of the 1994 Annual Energy Outlook (AEO94) forecasts. The report catalogues and describes modeling assumptions, computational methodologies, data inputs, and parameter estimation techniques. A number of offline analyses used in lieu of RFM modeling components are also described. This documentation report serves two purposes. First, it is a reference document for model analysts, model users, and the public interested in the construction and application of the RFM. Second, it meets the legal requirement of the Energy Information Administration (EIA) to provide adequate documentation in support of its models. The RFM consists of six analytical submodules that represent each of the major renewable energy resources -- wood, municipal solid waste (MSW), solar energy, wind energy, geothermal energy, and alcohol fuels. Of these six, four are documented in the following chapters: municipal solid waste, wind, solar and biofuels. Geothermal and wood are not currently working components of NEMS. The purpose of the RFM is to define the technological and cost characteristics of renewable energy technologies, and to pass these characteristics to other NEMS modules for the determination of mid-term forecasted renewable energy demand.

  19. MODELING THE DEMAND FOR E85 IN THE UNITED STATES

    SciTech Connect (OSTI)

    Liu, Changzheng [ORNL; Greene, David L [ORNL

    2013-10-01T23:59:59.000Z

    How demand for E85 might evolve in the future in response to changing economics and policies is an important subject to include in the National Energy Modeling System (NEMS). This report summarizes a study to develop an E85 choice model for NEMS. Using the most recent data from the states of Minnesota, North Dakota, and Iowa, this study estimates a logit model that represents E85 choice as a function of prices of E10 and E85, as well as fuel availability of E85 relative to gasoline. Using more recent data than previous studies allows a better estimation of non-fleet demand and indicates that the price elasticity of E85 choice appears to be higher than previously estimated. Based on the results of the econometric analysis, a model for projecting E85 demand at the regional level is specified. In testing, the model produced plausible predictions of US E85 demand to 2040.

  20. active user involvement: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    architecture. DBS was implemented on the Nano-Threads Programming Model (NPM) as part of NANOS, a large-scale project involving the development of a runtime...

  1. NEMS Freight Transportation Module Improvement Study

    U.S. Energy Information Administration (EIA) Indexed Site

    basic shapes 33. Articles of base metal 41. Waste and scrap 3. Processed food 5. Meat, fish, seafood, and their preparations 6. Milled grain products and preparations, and bakery...

  2. Model documentation renewable fuels module of the National Energy Modeling System

    SciTech Connect (OSTI)

    NONE

    1995-06-01T23:59:59.000Z

    This report documents the objectives, analytical approach, and design of the National Energy Modeling System (NEMS) Renewable Fuels Module (RFM) as it relates to the production of the 1995 Annual Energy Outlook (AEO95) forecasts. The report catalogues and describes modeling assumptions, computational methodologies, data inputs, and parameter estimation techniques. A number of offline analyses used in lieu of RFM modeling components are also described. The RFM consists of six analytical submodules that represent each of the major renewable energy resources--wood, municipal solid waste (MSW), solar energy, wind energy, geothermal energy, and alcohol fuels. The RFM also reads in hydroelectric facility capacities and capacity factors from a data file for use by the NEMS Electricity Market Module (EMM). The purpose of the RFM is to define the technological, cost and resource size characteristics of renewable energy technologies. These characteristics are used to compute a levelized cost to be competed against other similarly derived costs from other energy sources and technologies. The competition of these energy sources over the NEMS time horizon determines the market penetration of these renewable energy technologies. The characteristics include available energy capacity, capital costs, fixed operating costs, variable operating costs, capacity factor, heat rate, construction lead time, and fuel product price.

  3. STUDENT EMPLOYMENT Student Involvement Outcomes

    E-Print Network [OSTI]

    de Lijser, Peter

    STUDENT EMPLOYMENT Student Involvement Outcomes reflective assessment High impact practices. Employment Structure ASI employs approximately 645 staff, interns, and volunteers on average during the fall and spring semesters. In spring 2013, ASI employed: · 42 Interns · 59 Professional Staff Members · 162

  4. Transportation Sector Model of the National Energy Modeling System. Volume 1

    SciTech Connect (OSTI)

    NONE

    1998-01-01T23:59:59.000Z

    This report documents the objectives, analytical approach and development of the National Energy Modeling System (NEMS) Transportation Model (TRAN). The report catalogues and describes the model assumptions, computational methodology, parameter estimation techniques, model source code, and forecast results generated by the model. The NEMS Transportation Model comprises a series of semi-independent models which address different aspects of the transportation sector. The primary purpose of this model is to provide mid-term forecasts of transportation energy demand by fuel type including, but not limited to, motor gasoline, distillate, jet fuel, and alternative fuels (such as CNG) not commonly associated with transportation. The current NEMS forecast horizon extends to the year 2010 and uses 1990 as the base year. Forecasts are generated through the separate consideration of energy consumption within the various modes of transport, including: private and fleet light-duty vehicles; aircraft; marine, rail, and truck freight; and various modes with minor overall impacts, such as mass transit and recreational boating. This approach is useful in assessing the impacts of policy initiatives, legislative mandates which affect individual modes of travel, and technological developments. The model also provides forecasts of selected intermediate values which are generated in order to determine energy consumption. These elements include estimates of passenger travel demand by automobile, air, or mass transit; estimates of the efficiency with which that demand is met; projections of vehicle stocks and the penetration of new technologies; and estimates of the demand for freight transport which are linked to forecasts of industrial output. Following the estimation of energy demand, TRAN produces forecasts of vehicular emissions of the following pollutants by source: oxides of sulfur, oxides of nitrogen, total carbon, carbon dioxide, carbon monoxide, and volatile organic compounds.

  5. Model documentation report: Transportation sector model of the National Energy Modeling System

    SciTech Connect (OSTI)

    Not Available

    1994-03-01T23:59:59.000Z

    This report documents the objectives, analytical approach and development of the National Energy Modeling System (NEMS) Transportation Model (TRAN). The report catalogues and describes the model assumptions, computational methodology, parameter estimation techniques, model source code, and forecast results generated by the model. This document serves three purposes. First, it is a reference document providing a detailed description of TRAN for model analysts, users, and the public. Second, this report meets the legal requirements of the Energy Information Administration (EIA) to provide adequate documentation in support of its statistical and forecast reports (Public Law 93-275, 57(b)(1)). Third, it permits continuity in model development by providing documentation from which energy analysts can undertake model enhancements, data updates, and parameter refinements.

  6. Model documentation renewable fuels module of the National Energy Modeling System

    SciTech Connect (OSTI)

    NONE

    1997-04-01T23:59:59.000Z

    This report documents the objectives, analytical approach, and design of the National Energy Modeling System (NEMS) Renewable Fuels Module (RFM) as it relates to the production of the 1997 Annual Energy Outlook forecasts. The report catalogues and describes modeling assumptions, computational methodologies, data inputs. and parameter estimation techniques. A number of offline analyses used in lieu of RFM modeling components are also described. This documentation report serves three purposes. First, it is a reference document for model analysts, model users, and the public interested in the construction and application of the RFM. Second, it meets the legal requirement of the Energy Information Administration (EIA) to provide adequate documentation in support of its models. Finally, such documentation facilitates continuity in EIA model development by providing information sufficient to perform model enhancements and data updates as part of EIA`s ongoing mission to provide analytical and forecasting information systems.

  7. Cyber Incidents Involving Control Systems

    SciTech Connect (OSTI)

    Robert J. Turk

    2005-10-01T23:59:59.000Z

    The Analysis Function of the US-CERT Control Systems Security Center (CSSC) at the Idaho National Laboratory (INL) has prepared this report to document cyber security incidents for use by the CSSC. The description and analysis of incidents reported herein support three CSSC tasks: establishing a business case; increasing security awareness and private and corporate participation related to enhanced cyber security of control systems; and providing informational material to support model development and prioritize activities for CSSC. The stated mission of CSSC is to reduce vulnerability of critical infrastructure to cyber attack on control systems. As stated in the Incident Management Tool Requirements (August 2005) ''Vulnerability reduction is promoted by risk analysis that tracks actual risk, emphasizes high risk, determines risk reduction as a function of countermeasures, tracks increase of risk due to external influence, and measures success of the vulnerability reduction program''. Process control and Supervisory Control and Data Acquisition (SCADA) systems, with their reliance on proprietary networks and hardware, have long been considered immune to the network attacks that have wreaked so much havoc on corporate information systems. New research indicates this confidence is misplaced--the move to open standards such as Ethernet, Transmission Control Protocol/Internet Protocol, and Web technologies is allowing hackers to take advantage of the control industry's unawareness. Much of the available information about cyber incidents represents a characterization as opposed to an analysis of events. The lack of good analyses reflects an overall weakness in reporting requirements as well as the fact that to date there have been very few serious cyber attacks on control systems. Most companies prefer not to share cyber attack incident data because of potential financial repercussions. Uniform reporting requirements will do much to make this information available to Department of Homeland Security (DHS) and others who require it. This report summarizes the rise in frequency of cyber attacks, describes the perpetrators, and identifies the means of attack. This type of analysis, when used in conjunction with vulnerability analyses, can be used to support a proactive approach to prevent cyber attacks. CSSC will use this document to evolve a standardized approach to incident reporting and analysis. This document will be updated as needed to record additional event analyses and insights regarding incident reporting. This report represents 120 cyber security incidents documented in a number of sources, including: the British Columbia Institute of Technology (BCIT) Industrial Security Incident Database, the 2003 CSI/FBI Computer Crime and Security Survey, the KEMA, Inc., Database, Lawrence Livermore National Laboratory, the Energy Incident Database, the INL Cyber Incident Database, and other open-source data. The National Memorial Institute for the Prevention of Terrorism (MIPT) database was also interrogated but, interestingly, failed to yield any cyber attack incidents. The results of this evaluation indicate that historical evidence provides insight into control system related incidents or failures; however, that the limited available information provides little support to future risk estimates. The documented case history shows that activity has increased significantly since 1988. The majority of incidents come from the Internet by way of opportunistic viruses, Trojans, and worms, but a surprisingly large number are directed acts of sabotage. A substantial number of confirmed, unconfirmed, and potential events that directly or potentially impact control systems worldwide are also identified. Twelve selected cyber incidents are presented at the end of this report as examples of the documented case studies (see Appendix B).

  8. Studies involving low protein broiler diets

    E-Print Network [OSTI]

    Parkin, David Palmer

    1971-01-01T23:59:59.000Z

    STUDIES INVOLVING L(% PROTEIN BROILER DIETS A Thesis by David Palmer Parkin Submitted to the Graduate College of Texas A&M University in partial fulfillment of the requirement for the degree of MASTER OF SCIENCE May 1971 Major Subject...: Poultry Science STUDIES INVOLVING LS& PROTEIN BROILER DIETS A Thesis by David Palmer Parkin Approved as to style and content by: (Chairman of Commit e) ead of. Departmen Me er) (Member) (Memb ) May 1971 ABSTRACT Studies Involving Low Protein...

  9. The Leadership and Involvement Record Sponsored by the Center for Leadership and Involvement

    E-Print Network [OSTI]

    Sheridan, Jennifer

    The Leadership and Involvement Record Sponsored by the Center for Leadership and Involvement The Leadership and Involvement Record is an official document from the University of Wisconsin recording the leadership roles, student org involvement, or group membership students have had on campus. The record

  10. Graphic Designer Student Involvement and Leadership

    E-Print Network [OSTI]

    Subramanian, Venkat

    Graphic Designer Student Involvement and Leadership Position Overview The Graphic Designer standards of the Student Involvement and Leadership brand guardrails · Complete other duties as assigned-Design, and Illustrator · Must have experience creating print and web graphics, flyers, and other promotional materials

  11. Prefrontal involvement in the regulation of emotion: convergence of rat and human studies

    E-Print Network [OSTI]

    Quirk, Gregory J.

    experiments designed to bridge human and rodent models of emotion regulation. Addresses 1 Department of prefrontal involvement of emotion regula- tion using rat and human models, and suggest future experimentsPrefrontal involvement in the regulation of emotion: convergence of rat and human studies Gregory J

  12. Model documentation report: Commercial Sector Demand Module of the National Energy Modeling System

    SciTech Connect (OSTI)

    NONE

    1995-02-01T23:59:59.000Z

    This report documents the objectives, analytical approach and development of the National Energy Modeling System (NEMS) Commercial Sector Demand Module. The report catalogues and describes the model assumptions, computational methodology, parameter estimation techniques, model source code, and forecast results generated through the synthesis and scenario development based on these components. This report serves three purposes. First, it is a reference document providing a detailed description for model analysts, users, and the public. Second, this report meets the legal requirement of the Energy Information Administration (EIA) to provide adequate documentation in support of its statistical and forecast reports (Public Law 93-275, section 57(b)(1)). Third, it facilitates continuity in model development by providing documentation from which energy analysts can undertake model enhancements, data updates, and parameter refinements as future projects.

  13. Renewable Energy and Efficiency Modeling Analysis Partnership: An Analysis of How Different Energy Models Addressed a Common High Renewable Energy Penetration Scenario in 2025

    E-Print Network [OSTI]

    Blair, N.

    2010-01-01T23:59:59.000Z

    ACORE AEO ANL BNL CCS DOE EERE EIA EMF EPA FERC IGCC IPM ITCmodels are IPM, HAIKU, NEMS-EIA, NEMS-GPRA, WinDS, NE-MARKALInformation Administration (EIA), the American Council for

  14. Factors Involved in Search Dog Training

    E-Print Network [OSTI]

    Alexander, Michael B.

    2010-07-14T23:59:59.000Z

    involved in training competent search dogs. Obedience training methods, age training was initiated, previous handler canine training experience, and handler perception and emotional attachment to their search dog were examined through a sixty-six question...

  15. New Method and Reporting of Uncertainty in LBNL National Energy Modeling System Runs

    E-Print Network [OSTI]

    Gumerman, Etan Z.; LaCommare, Kristina Hamachi; Marnay, Chris

    2002-01-01T23:59:59.000Z

    GPRA Runs 3. Conclusion LBNL set out to establish a standarduncertainty into typical, LBNL-NEMS runs completed for GPRAwill be produced together with all future LBNL-NEMS runs.

  16. COMMUNITY INVOLVEMENT PLAN APRIL 15, 1999.

    SciTech Connect (OSTI)

    GEIGER,K.

    1999-04-15T23:59:59.000Z

    This Community Involvement Plan has been prepared by the Brookhaven National Laboratory's Community Involvement Office with the input of the community, Laboratory employees and representatives of the U.S. Department of Energy. The process to develop the plan began with the formation of a focus group consisting of representatives from: the community at large; special interest groups within the community; the business community; Laboratory retirees; senior and line management from the Laboratory; and the U.S. Department of Energy. The focus group reviewed an initial outline developed by the Office of Community involvement, held in-depth roundtable discussions of community involvement needs, and created a draft plan based on their discussions. A workshop was held to present the draft Community Involvement Plan to a wider audience for their input and insights on how Brookhaven should involve the community in decision making. This workshop was advertised in local newspapers and within the Laboratory. It was attended by community members, special interest group representatives, Laboratory employees and managers, U.S. Department of Energy-Brookhaven Group management, and members of the Laboratory's Community Advisory Council. The results of the workshop discussions are incorporated in this plan.

  17. Physical Models of Noncovalent Interactions Involving Aromatic Rings

    E-Print Network [OSTI]

    Bloom, Jacob Walter Goldstein

    2014-04-17T23:59:59.000Z

    of the interaction energies for sandwich dimers of Bz-X…Tz(N) versus Bz-X…Tz(C), at R = 4.0 Å. ............................................................................................................. 63 Figure 4.8: Electrostatic potential (solid colors, kcal...) for sandwich dimers of (a) Bz-X…Tz(C) versus Bz-X…Tz(N) and (b) Bz-X…Bz versus Bn(N)-X…Bz. ................................................................................................ 58 Figure 4.6: (a) Relative SAPT0 interaction energies (R = Re) and (b...

  18. Model documentation report: Residential sector demand module of the National Energy Modeling System

    SciTech Connect (OSTI)

    NONE

    1995-03-01T23:59:59.000Z

    This report documents the objectives, analytical approach, and development of the National Energy Modeling System (NEMS) Residential Sector Demand Module. The report catalogues and describes the model assumptions, computational methodology, parameter estimation techniques, and FORTRAN source code. This document serves three purposes. First, it is a reference document providing a detailed description for energy analysts, other users, and the public. Second, this report meets the legal requirement of the Energy Information Administration (EIA) to provide adequate documentation in support of its statistical and forecast reports according to Public Law 93-275, section 57(b)(1). Third, it facilitates continuity in model development by providing documentation from which energy analysts can undertake model enhancements, data updates, and parameter refinements.

  19. Frequency stabilization in nonlinear MEMS and NEMS oscillators

    DOE Patents [OSTI]

    Lopez, Omar Daniel; Antonio, Dario

    2014-09-16T23:59:59.000Z

    An illustrative system includes an amplifier operably connected to a phase shifter. The amplifier is configured to amplify a voltage from an oscillator. The phase shifter is operably connected to a driving amplitude control, wherein the phase shifter is configured to phase shift the amplified voltage and is configured to set an amplitude of the phase shifted voltage. The oscillator is operably connected to the driving amplitude control. The phase shifted voltage drives the oscillator. The oscillator is at an internal resonance condition, based at least on the amplitude of the phase shifted voltage, that stabilizes frequency oscillations in the oscillator.

  20. NEM Interpolant for Fourth-Order PDEs Internal Report

    E-Print Network [OSTI]

    Sukumar, N.

    Sibson's coordinate in the Bernstein-B#19;ezier representation of a cubic simplex, a C 1( interpolant and in the #12;eld of computer-aided geometric design [10]. A review article on triangular Bernstein- B#19;ezier of a simplex Ã? 2 R n 1 . A Bernstein-B#19;ezier surface of degree m over the simplex Ã? can be written

  1. U.S. Regional Demand Forecasts Using NEMS and GIS

    E-Print Network [OSTI]

    Cohen, Jesse A.; Edwards, Jennifer L.; Marnay, Chris

    2005-01-01T23:59:59.000Z

    Administration. 2004a. Annual Energy Outlook 2004. U.S.Assumptions of the Annual Energy Outlook 2004. DOE/EIA-0554(and Definitions AEO – Annual Energy Outlook ArcGIS - ESRI

  2. EIA Buildings Analysis of Consumer Behavior in NEMS

    U.S. Energy Information Administration (EIA) Indexed Site

    2015 2020 2025 2030 2035 2040 0 2 4 6 8 10 12 14 16 2010 2015 2020 2025 2030 2035 2040 PV Wind Natural gas Other For more information 15 Behavioral Economics Experts Meeting,...

  3. Appendix C: Map of NEMS Electricity Market Module Regions

    Annual Energy Outlook 2013 [U.S. Energy Information Administration (EIA)]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742 33 111 1,613 122 40CoalLease(Billion CubicPotentialNov-14 Dec-14 Jan-1538,469Appendix E44 Reference4

  4. Analysis and Representation of Miscellaneous Electric Loads in NEMS -

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for On-Highway4,1,50022,3,,,,6,1,9,1,50022,3,,,,6,1,Decade Year-0E (2001)gasoline prices4 OilU.S. OffshoreOil andEnergy

  5. Overview of NEMS-H2, Version 1.0

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn'tOrigin of Contamination in ManyDepartmentOutreach toTransmissionProgramTechnologies

  6. NEMS Freight Transportation Module Improvement Study - Energy Information

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Saleshttp://www.fnal.gov/directorate/nalcal/nalcal02_07_05_files/nalcal.gif Directorate - Events - Fermilab

  7. Environmental science and ecology involve studies

    E-Print Network [OSTI]

    Christensen, Dan

    Environmental science and ecology involve studies of the biosphere, hydro- sphere, and lithosphere in environmental science is conducted on spatial scales varying from a single algal cell to the Earth as a whole's environmental scientists require investigation by an interdisciplinary team, including members from several

  8. Increasing Public Involvement in Structural Biology

    E-Print Network [OSTI]

    Baker, David

    --often referred to as citizen science--provides a means of engaging people's skills, rather than just for the public to get actively involved in structural biology research? Citizen science projects can require areas for citizen science as structural problems both are amenable to human spatial-reasoning skills

  9. Undergraduate business and management students’ experiences of being involved in assessment 

    E-Print Network [OSTI]

    Tai, Chunming

    2012-11-29T23:59:59.000Z

    This study aimed to explore university undergraduates’ experiences of student involvement in assessment (SIA). Based on Biggs’ 3P model of student learning, this study focused on students’ experiences prior to SIA, during ...

  10. Model documentation: Electricity market module, electricity finance and pricing submodule

    SciTech Connect (OSTI)

    Not Available

    1994-04-07T23:59:59.000Z

    The purpose of this report is to define the objectives of the model, describe its basic approach, and provide detail on how it works. The EFP is a regulatory accounting model that projects electricity prices. The model first solves for revenue requirements by building up a rate base, calculating a return on rate base, and adding the allowed expenses. Average revenues (prices) are calculated based on assumptions regarding regulator lag and customer cost allocation methods. The model then solves for the internal cash flow and analyzes the need for external financing to meet necessary capital expenditures. Finally, the EFP builds up the financial statements. The EFP is used in conjunction with the National Energy Modeling System (NEMS). Inputs to the EFP include the forecast generating capacity expansion plans, operating costs, regulator environment, and financial data. The outputs include forecasts of income statements, balance sheets, revenue requirements, and electricity prices.

  11. Regulation of the genes involved in nitrification.

    SciTech Connect (OSTI)

    Arp, D.J.; Sayavedra-Soto, L.A.

    2003-08-14T23:59:59.000Z

    OAK-B135 This project focuses on the characterization of the regulation of the genes involved in nitrification in the bacterium Nitrosomonas europaea. The key genes in the nitrification pathway, amo and hao, are present in multiple copies in the genome. The promoters for these genes were identified and characterized. It was shown that there were some differences in the transcriptional regulation of the copies of these genes.

  12. Community Involvement Fund | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE: Alternative FuelsNovember 13, 2014 BuildingEnergy EfficiencyPast ProjectsCommunity Involvement

  13. UPDATING THE FREIGHT TRUCK STOCK ADJUSTMENT MODEL: 1997 VEHICLE INVENTORY AND USE SURVEY DATA

    SciTech Connect (OSTI)

    Davis, S.C.

    2000-11-16T23:59:59.000Z

    The Energy Information Administration's (EIA's) National Energy Modeling System (NEMS) Freight Truck Stock Adjustment Model (FTSAM) was created in 1995 relying heavily on input data from the 1992 Economic Census, Truck Inventory and Use Survey (TIUS). The FTSAM is part of the NEMS Transportation Sector Model, which provides baseline energy projections and analyzes the impacts of various technology scenarios on consumption, efficiency, and carbon emissions. The base data for the FTSAM can be updated every five years as new Economic Census information is released. Because of expertise in using the TIUS database, Oak Ridge National Laboratory (ORNL) was asked to assist the EIA when the new Economic Census data were available. ORNL provided the necessary base data from the 1997 Vehicle Inventory and Use Survey (VIUS) and other sources to update the FTSAM. The next Economic Census will be in the year 2002. When those data become available, the EIA will again want to update the FTSAM using the VIUS. This report, which details the methodology of estimating and extracting data from the 1997 VIUS Microdata File, should be used as a guide for generating the data from the next VIUS so that the new data will be as compatible as possible with the data in the model.

  14. Apolipoprotein gene involved in lipid metabolism

    DOE Patents [OSTI]

    Rubin, Edward (Berkeley, CA); Pennacchio, Len A. (Sebastopol, CA)

    2007-07-03T23:59:59.000Z

    Methods and materials for studying the effects of a newly identified human gene, APOAV, and the corresponding mouse gene apoAV. The sequences of the genes are given, and transgenic animals which either contain the gene or have the endogenous gene knocked out are described. In addition, single nucleotide polymorphisms (SNPs) in the gene are described and characterized. It is demonstrated that certain SNPs are associated with diseases involving lipids and triglycerides and other metabolic diseases. These SNPs may be used alone or with SNPs from other genes to study individual risk factors. Methods for intervention in lipid diseases, including the screening of drugs to treat lipid-related or diabetic diseases are also disclosed.

  15. Modeling Interregional Transmission Congestion in the National Energy Modeling System

    E-Print Network [OSTI]

    Gumerman, Etan; Chan, Peter; Lesieutre, Bernard; Marnay, Chris; Wang, Juan

    2006-01-01T23:59:59.000Z

    Total Number of New Plants Generating Capacity 7.2 GW 15.7that NEMS builds for generating plants, which are dedicatedOnly certain types of generating plants can be built off the

  16. What is the effect of 4-H involvement on levels of empathy, self-esteem, community involvement and positive view of the future on urban youth?

    E-Print Network [OSTI]

    Bonnett, Erika Dawn

    2007-04-25T23:59:59.000Z

    , self-esteem, positive view of the future, and community involvement. The study utilized a quantitative research model in which a survey was taken of youth presiding in urban areas in the state of Texas. Descriptive statistics were used to report subject...

  17. Genomic Aspects of Research Involving Polyploid Plants

    SciTech Connect (OSTI)

    Yang, Xiaohan [ORNL; Ye, Chuyu [ORNL; Tschaplinski, Timothy J [ORNL; Wullschleger, Stan D [ORNL; Tuskan, Gerald A [ORNL

    2011-01-01T23:59:59.000Z

    Almost all extant plant species have spontaneously doubled their genomes at least once in their evolutionary histories, resulting in polyploidy which provided a rich genomic resource for evolutionary processes. Moreover, superior polyploid clones have been created during the process of crop domestication. Polyploid plants generated by evolutionary processes and/or crop domestication have been the intentional or serendipitous focus of research dealing with the dynamics and consequences of genome evolution. One of the new trends in genomics research is to create synthetic polyploid plants which provide materials for studying the initial genomic changes/responses immediately after polyploid formation. Polyploid plants are also used in functional genomics research to study gene expression in a complex genomic background. In this review, we summarize the recent progress in genomics research involving ancient, young, and synthetic polyploid plants, with a focus on genome size evolution, genomics diversity, genomic rearrangement, genetic and epigenetic changes in duplicated genes, gene discovery, and comparative genomics. Implications on plant sciences including evolution, functional genomics, and plant breeding are presented. It is anticipated that polyploids will be a regular subject of genomics research in the foreseeable future as the rapid advances in DNA sequencing technology create unprecedented opportunities for discovering and monitoring genomic and transcriptomic changes in polyploid plants. The fast accumulation of knowledge on polyploid formation, maintenance, and divergence at whole-genome and subgenome levels will not only help plant biologists understand how plants have evolved and diversified, but also assist plant breeders in designing new strategies for crop improvement.

  18. Surface interactions involved in flashover with high density electronegative gases.

    SciTech Connect (OSTI)

    Hodge, Keith Conquest; Warne, Larry Kevin; Jorgenson, Roy Eberhardt; Wallace, Zachariah Red; Lehr, Jane Marie

    2010-01-01T23:59:59.000Z

    This report examines the interactions involved with flashover along a surface in high density electronegative gases. The focus is on fast ionization processes rather than the later time ionic drift or thermalization of the discharge. A kinetic simulation of the gas and surface is used to examine electron multiplication and includes gas collision, excitation and ionization, and attachment processes, gas photoionization and surface photoemission processes, as well as surface attachment. These rates are then used in a 1.5D fluid ionization wave (streamer) model to study streamer propagation with and without the surface in air and in SF6. The 1.5D model therefore includes rates for all these processes. To get a better estimate for the behavior of the radius we have studied radial expansion of the streamer in air and in SF6. The focus of the modeling is on voltage and field level changes (with and without a surface) rather than secondary effects, such as, velocities or changes in discharge path. An experiment has been set up to carry out measurements of threshold voltages, streamer velocities, and other discharge characteristics. This setup includes both electrical and photographic diagnostics (streak and framing cameras). We have observed little change in critical field levels (where avalanche multiplication sets in) in the gas alone versus with the surface. Comparisons between model calculations and experimental measurements are in agreement with this. We have examined streamer sustaining fields (field which maintains ionization wave propagation) in the gas and on the surface. Agreement of the gas levels with available literature is good and agreement between experiment and calculation is good also. Model calculations do not indicate much difference between the gas alone versus the surface levels. Experiments have identified differences in velocity between streamers on the surface and in the gas alone (the surface values being larger).

  19. Public involvement in radioactive waste management decisions

    SciTech Connect (OSTI)

    NONE

    1994-04-01T23:59:59.000Z

    Current repository siting efforts focus on Yucca Mountain, Nevada, where DOE`s Office of Civilian Radioactive Waste Management (OCRWM) is conducting exploratory studies to determine if the site is suitable. The state of Nevada has resisted these efforts: it has denied permits, brought suit against DOE, and publicly denounced the federal government`s decision to study Yucca Mountain. The state`s opposition reflects public opinion in Nevada, and has considerably slowed DOE`s progress in studying the site. The Yucca Mountain controversy demonstrates the importance of understanding public attitudes and their potential influence as DOE develops a program to manage radioactive waste. The strength and nature of Nevada`s opposition -- its ability to thwart if not outright derail DOE`s activities -- indicate a need to develop alternative methods for making decisions that affect the public. This report analyzes public participation as a key component of this openness, one that provides a means of garnering acceptance of, or reducing public opposition to, DOE`s radioactive waste management activities, including facility siting and transportation. The first section, Public Perceptions: Attitudes, Trust, and Theory, reviews the risk-perception literature to identify how the public perceives the risks associated with radioactivity. DOE and the Public discusses DOE`s low level of credibility among the general public as the product, in part, of the department`s past actions. This section looks at the three components of the radioactive waste management program -- disposal, storage, and transportation -- and the different ways DOE has approached the problem of public confidence in each case. Midwestern Radioactive Waste Management Histories focuses on selected Midwestern facility-siting and transportation activities involving radioactive materials.

  20. Hydrogen Bonds Involved in Binding the Qi-site Semiquinone in the bc1 Complex, Identified through Deuterium Exchange

    E-Print Network [OSTI]

    Crofts, Antony R.

    Hydrogen Bonds Involved in Binding the Qi-site Semiquinone in the bc1 Complex, Identified through them. The strength of interactions indicates that the protons are involved in hydrogen bonds with SQ. The hyperfine cou- plings differ from values typical for in-plane hydrogen bonds previously observed in model

  1. A Self-advocacy Program for Students with Disabilities: Adult Outcomes and Advocacy Involvement One to Six Years after Involvement

    E-Print Network [OSTI]

    Roberts, Eric

    2013-03-08T23:59:59.000Z

    attendance was higher than the national average for adults with disabilities. Participants with low incidence disabilities were involved in inclusive employment more often than the national average. A minority status increased the likelihood of involvement...

  2. DEA Efficiency Analysis Involving Multiple Production Processes with an Application to

    E-Print Network [OSTI]

    Illinois at Chicago, University of

    with which input resources are allocated to the subunits. It introduces a simple model for efficientlyDEA Efficiency Analysis Involving Multiple Production Processes with an Application to Urban Mass in the Department of Information Systems and Technology within in the College of Business Administration

  3. Electronic spectroscopy of intermediates involved in the conversion of methane to methanol by FeO

    E-Print Network [OSTI]

    Metz, Ricardo B.

    Electronic spectroscopy of intermediates involved in the conversion of methane to methanol by Fe.1063/1.1448489 I. INTRODUCTION The direct oxidation of methane to an easily transport- able liquid such as methanol process and as the simplest model for alkane oxidation.1,2 Although no direct, efficient methane­methanol

  4. Distributional properties of Euclidean distances in wireless networks involving road systems

    E-Print Network [OSTI]

    Schmidt, Volker

    1 Distributional properties of Euclidean distances in wireless networks involving road systems of large wireless networks. The network geometry is modelled by random geometric graphs, and the locations are closely related with the interference geometry and, consequently, the performance of wireless networks

  5. RISK ASSESSMENT OF A FIRE INVOLVING COMBUSTIBLE MATERIALS IN A WAREHOUSE

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    in "4. International seminar on fire and explosion hazards, Londonderry : Ireland (2003)" #12;SeRISK ASSESSMENT OF A FIRE INVOLVING COMBUSTIBLE MATERIALS IN A WAREHOUSE Wang, H.Y. ', Russo, P modeling into a rack fire in warehouse, and an identifi- cation of the visible flame shape when a fire

  6. Involvement of astrocyte metabolic coupling in Tourette syndrome pathogenesis

    E-Print Network [OSTI]

    2015-01-01T23:59:59.000Z

    Magistretti PJ: Brain energy metabolism: focus on astrocyte?involved  in  various  energy  metabolism  processes  that cycle for oxidative energy metabolism and for production of 

  7. Microsoft Word - Number of Public Involvement Deliverables _2...

    National Nuclear Security Administration (NNSA)

    numerous (+150) video clips and raw video * Maintain the Public Involvement portion of web-based Environmental Management Information System (includes uploading briefings,...

  8. activity involving yb-1: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  9. adenylyl cyclase involved: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  10. ahr repressor involving: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  11. anaemia potential involvement: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  12. antigens predominant involvement: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  13. actinobacillus pleuropneumoniae involved: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  14. aedes aegypti involvement: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  15. accidental fatalities involving: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  16. adenosinergic system involvement: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  17. aspergillus nidulans involves: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  18. aminoguanidine involve reduced: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  19. arteriovenous malformations involving: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  20. alternata involves active: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  1. anterior prefrontal involvement: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  2. adjuvant involved field: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  3. asymptomatic lymphangioma involving: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  4. alternaria alternata involves: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  5. antinociception involves endogenous: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  6. apoptosis involving activation: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  7. arteriovenous malformation involving: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  8. accidents involving external: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    25 Next Page Last Page Topic Index 1 Development and use of the ESReDA directory of accident databases involving chemicals Computer Technologies and Information Sciences Websites...

  9. INVOLVED IN DE NOVO 2-containing complex involved in RNA-directed DNA methylation in Arabidopsis

    SciTech Connect (OSTI)

    Ausin, Israel; Greenberg, Maxim V.C.; Simanshu, Dhirendra K.; Hale, Christopher J.; Vashisht, Ajay A.; Simon, Stacey A.; Lee, Tzuu-fen; Feng, Suhua; Española, Sophia D.; Meyers, Blake C.; Wohlschlegel, James A.; Patel, Dinshaw J.; Jacobsen, Steven E. (UCLA); (MSKCC); (Delaware)

    2012-10-23T23:59:59.000Z

    At least three pathways control maintenance of DNA cytosine methylation in Arabidopsis thaliana. However, the RNA-directed DNA methylation (RdDM) pathway is solely responsible for establishment of this silencing mark. We previously described INVOLVED IN DE NOVO 2 (IDN2) as being an RNA-binding RdDM component that is required for DNA methylation establishment. In this study, we describe the discovery of two partially redundant proteins that are paralogous to IDN2 and that form a stable complex with IDN2 in vivo. Null mutations in both genes, termed IDN2-LIKE 1 and IDN2-LIKE 2 (IDNL1 and IDNL2), result in a phenotype that mirrors, but does not further enhance, the idn2 mutant phenotype. Genetic analysis suggests that this complex acts in a step in the downstream portion of the RdDM pathway. We also have performed structural analysis showing that the IDN2 XS domain adopts an RNA recognition motif (RRM) fold. Finally, genome-wide DNA methylation and expression analysis confirms the placement of the IDN proteins in an RdDM pathway that affects DNA methylation and transcriptional control at many sites in the genome. Results from this study identify and describe two unique components of the RdDM machinery, adding to our understanding of DNA methylation control in the Arabidopsis genome.

  10. LESSONS LEARNED FROM A LANDFILL SLOPE FAILURE INVOLVING

    E-Print Network [OSTI]

    LESSONS LEARNED FROM A LANDFILL SLOPE FAILURE INVOLVING GEOSYTNTHETICS Virginia L. Wilson: Geosynthetics: Lessons Learned from Failures International Geosynthetics Society editors J.P. Giroud, K.L. Soderman and G.P. Raymond November 12, 1998 #12;LESSONS LEARNED FROM A LANDFILL SLOPE FAILURE INVOLVING

  11. Lessons Learned from Failures Involving Geofoam in Roads and Embankments

    E-Print Network [OSTI]

    Horvath, John S.

    Lessons Learned from Failures Involving Geofoam in Roads and Embankments Manhattan College Research July 1999) #12;Lessons Learned from Failures Involving Geofoam in Roads and Embankments Manhattan College Research Report No. CE/GE-99-1 ii This page intentionally left blank. #12;Lessons Learned from

  12. Citizen Involvement in Water Resources Issues in New England

    E-Print Network [OSTI]

    Gold, Art

    was developed and conducted in May of 2005. This survey was based on a template developed in the PacificCitizen Involvement in Water Resources Issues in New England Abstract A survey determined citizen the degree of current citizen involvement in water resources issues in New England, a public opinion survey

  13. Voluntary Associations and Their Involvement in Collaborative Forest Management

    E-Print Network [OSTI]

    Lu, Jiaying

    2012-02-14T23:59:59.000Z

    . This dissertation was aimed at gaining a better understanding of outdoor recreation and environmental voluntary associations and their involvement in collaborative forest management. Five objectives guided this study: (1) assessing the organizational characteristics...

  14. Unsaturated geotechnics applied to geoenvironmental engineering problems involving geosynthetics

    E-Print Network [OSTI]

    Zornberg, Jorge G.

    such as geotextiles and geosynthetic clay liners (GCLs) with particular focus on capillary barriers, liner performanceUnsaturated geotechnics applied to geoenvironmental engineering problems involving geosynthetics Available online 15 February 2013 Keywords: Capillary break Desiccation Flow Geosynthetics Interface shear

  15. A fast enriched FEM for Poisson equations involving interfaces

    E-Print Network [OSTI]

    Huynh, Thanh Le Ngoc

    2008-01-01T23:59:59.000Z

    We develop a fast enriched finite element method for solving Poisson equations involving complex geometry interfaces by using regular Cartesian grids. The presence of interfaces is accounted for by developing suitable jump ...

  16. Effects of Parent Expectations and Involvement on the School Readiness of Children in Head Start

    E-Print Network [OSTI]

    Cook, Krystal Tisha'

    2010-10-12T23:59:59.000Z

    EFFECTS OF PARENT EXPECTATIONS AND INVOLVEMENT ON THE SCHOOL READINESS OF CHILDREN IN HEAD START A Dissertation by KRYSTAL TISHA? COOK Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment... of children enrolled in Head Start. The study examined how these iv parent variables were related to children?s school readiness, and differences between ethnic groups, gender groups, and level of risk. The study tested a model whereby the effect...

  17. Documentation of the DRI Model of the US economy, December 1993

    SciTech Connect (OSTI)

    Not Available

    1994-02-28T23:59:59.000Z

    The Energy Information Administration (EIA) uses models of the US economy developed by Data Resources, Inc. (DRI) for conducting policy analyses, preparing forecasts for the Annual Energy Outlook, the Short-Term Energy Outlook, and related analyses in conjunction with EIA`s National Energy Modeling System (NEMS) and its other energy market models. Both the DRI Model of the US Economy and the DRI Personal Computer Input-Output Model (PC-IO){sup 2} were developed and are maintained by DRI as proprietary models. This report provides documentation, as required by EIA standards for the use of proprietary models; describes the theoretical basis, structure and functions of both DRI models; and contains brief descriptions of the models and their equations. Appendix A describes how the two large-scale models documented here are used to support the macroeconomic and interindustry modeling associated with the National Energy Modeling System. Appendix B is an article by Stephen McNees of the Federal Reserve Bank of Boston on ``How Large are Economic Forecast Errors.`` This article assesses the forecast accuracy of a number of economic forecasting models (groups) and is attached as an independent assessment of the forecast accuracy of the DRI Model of the US Economy.

  18. Model documentation natural gas transmission and distribution model (NGTDM) of the national energy modeling system. Volume II: Model developer`s report

    SciTech Connect (OSTI)

    Not Available

    1995-01-03T23:59:59.000Z

    To partially fulfill the requirements for {open_quotes}Model Acceptance{close_quotes} as stipulated in EIA Standard 91-01-01 (effective February 3, 1991), the Office of Integrated Analysis and Forecasting has conducted tests of the Natural Gas Transmission and Distribution Model (NGTDM) for the specific purpose of validating the forecasting model. This volume of the model documentation presents the results of {open_quotes}one-at-a-time{close_quotes} sensitivity tests conducted in support of this validation effort. The test results are presented in the following forms: (1) Tables of important model outputs for the years 2000 and 2010 are presented with respect to change in each input from the reference case; (2) Tables of percent changes from base case results for the years 2000 and 2010 are presented for important model outputs; (3) Tables of conditional sensitivities (percent change in output/percent change in input) for the years 2000 and 2010 are presented for important model outputs; (4) Finally, graphs presenting the percent change from base case results for each year of the forecast period are presented for selected key outputs. To conduct the sensitivity tests, two main assumptions are made in order to test the performance characteristics of the model itself and facilitate the understanding of the effects of the changes in the key input variables to the model on the selected key output variables: (1) responses to the amount demanded do not occur since there are no feedbacks of inputs from other NEMS models in the stand-alone NGTDM run. (2) All the export and import quantities from and to Canada and Mexico, and liquefied natural gas (LNG) imports and exports are held fixed (i.e., there are no changes in imports and exports between the reference case and the sensitivity cases) throughout the forecast period.

  19. A new 3-D EDDY current model

    SciTech Connect (OSTI)

    Polak, S.J.; van Welij, J.S.; Wachters, A.J.H.

    1983-11-01T23:59:59.000Z

    This paper presents a new EDDY current model. This model minimizes the number of unknown per point. The authors also discuss the uniqueness aspects involved.

  20. Final report on the public involvement process phase 1, Monitored Retrievable Storage Facility Feasibility Study

    SciTech Connect (OSTI)

    Moore, L.; Shanteau, C.

    1992-12-01T23:59:59.000Z

    This report summarizes the pubic involvement component of Phase 1 of the Monitored Retrievable Storage Facility (NM) Feasibility Study in San Juan County, Utah. Part of this summary includes background information on the federal effort to locate a voluntary site for temporary storage of nuclear waste, how San Juan County came to be involved, and a profile of the county. The heart of the report, however, summarizes the activities within the public involvement process, and the issues raised in those various forums. The authors have made every effort to reflect accurately and thoroughly all the concerns and suggestions expressed to us during the five month process. We hope that this report itself is a successful model of partnership with the citizens of the county -- the same kind of partnership the county is seeking to develop with its constituents. Finally, this report offers some suggestions to both county officials and residents alike. These suggestions concern how decision-making about the county's future can be done by a partnership of informed citizens and listening decision-makers. In the Appendix are materials relating to the public involvement process in San Juan County.

  1. Final report on the public involvement process phase 1, Monitored Retrievable Storage Facility Feasibility Study

    SciTech Connect (OSTI)

    Moore, L.; Shanteau, C.

    1992-12-01T23:59:59.000Z

    This report summarizes the pubic involvement component of Phase 1 of the Monitored Retrievable Storage Facility (NM) Feasibility Study in San Juan County, Utah. Part of this summary includes background information on the federal effort to locate a voluntary site for temporary storage of nuclear waste, how San Juan County came to be involved, and a profile of the county. The heart of the report, however, summarizes the activities within the public involvement process, and the issues raised in those various forums. The authors have made every effort to reflect accurately and thoroughly all the concerns and suggestions expressed to us during the five month process. We hope that this report itself is a successful model of partnership with the citizens of the county -- the same kind of partnership the county is seeking to develop with its constituents. Finally, this report offers some suggestions to both county officials and residents alike. These suggestions concern how decision-making about the county`s future can be done by a partnership of informed citizens and listening decision-makers. In the Appendix are materials relating to the public involvement process in San Juan County.

  2. Model documentation, Renewable Fuels Module of the National Energy Modeling System

    SciTech Connect (OSTI)

    NONE

    1998-01-01T23:59:59.000Z

    This report documents the objectives, analytical approach, and design of the National Energy Modeling System (NEMS) Renewable Fuels Module (RFM) as it relates to the production of the Annual Energy Outlook 1998 (AEO98) forecasts. The report catalogues and describes modeling assumptions, computational methodologies, data inputs, and parameter estimation techniques. A number of offline analyses used in lieu of RFM modeling components are also described. For AEO98, the RFM was modified in three principal ways, introducing capital cost elasticities of supply for new renewable energy technologies, modifying biomass supply curves, and revising assumptions for use of landfill gas from municipal solid waste (MSW). In addition, the RFM was modified in general to accommodate projections beyond 2015 through 2020. Two supply elasticities were introduced, the first reflecting short-term (annual) cost increases from manufacturing, siting, and installation bottlenecks incurred under conditions of rapid growth, and the second reflecting longer term natural resource, transmission and distribution upgrade, and market limitations increasing costs as more and more of the overall resource is used. Biomass supply curves were also modified, basing forest products supplies on production rather than on inventory, and expanding energy crop estimates to include states west of the Mississippi River using information developed by the Oak Ridge National Laboratory. Finally, for MSW, several assumptions for the use of landfill gas were revised and extended.

  3. A Protein Export Pathway Involving Escherichia coli Porins

    E-Print Network [OSTI]

    McIntosh, Lawrence P.

    Structure Article A Protein Export Pathway Involving Escherichia coli Porins Gerd Prehna,1,2 Guijin@byron.biochem.ubc.ca (N.C.J.S.) DOI 10.1016/j.str.2012.04.014 SUMMARY Escherichia coli export the protein Yeb common to all E. coli strains has been reported, the mechanism of export has remained unclear. Herein, we

  4. Formation Mechanism for a Hybrid Supramolecular Network Involving Cooperative Interactions

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Formation Mechanism for a Hybrid Supramolecular Network Involving Cooperative Interactions Manuela of Materials, University of Oxford, Parks Road, Oxford OX1 3PH, United Kingdom; CEA, IRAMIS, SPCSI, Hybrid University, 24-29 St Giles, Oxford, OX1 3LB, United Kingdom 4 Department of Materials, University of Oxford

  5. Nuclear Decommissioning and Organisational Reliability: Involving Subcontractors in Collective Action

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    Page 1 Nuclear Decommissioning and Organisational Reliability: Involving Subcontractors to the decommissioning. The use of subcontractors is not new; in the nuclear industry it became widespread in the 1990s reliability is at the heart of the safety of at-risk systems. Many studies have been conducted in the nuclear

  6. Research Article Acetylcholinesterase in intestinal cell differentiation involves

    E-Print Network [OSTI]

    Tian, Weidong

    involved in the terminal differentiation of enterocytes. Butyrate, a short-chain fatty acid produced in the colonic lumen by microbial fermentation, is taken up by cells of the intestinal epithelium, and serves of acetylcholine to choline and acetate. Interestingly, the expression of AChE is not restricted to cholinergic

  7. If the internship is international or involves international travel, the

    E-Print Network [OSTI]

    Hart, Gus

    If the internship is international or involves international travel, the student does not need to complete the IRAMS student internship ap- plication, but should contact the Kennedy Center for internship approval and course registration. Flag will be removed, and students will be able to add their internship

  8. If the internship is international or involves international travel, the

    E-Print Network [OSTI]

    Dahl, David B.

    If the internship is international or involves international travel, the student does not need to complete the IRAMS student internship application, but should contact the Kennedy Center for internship approval and course registration. Flag will be removed, and students will be able to add their internship

  9. ORIGINAL PAPER Expression of genes involved in energy mobilization

    E-Print Network [OSTI]

    Lee Jr., Richard E.

    ORIGINAL PAPER Expression of genes involved in energy mobilization and osmoprotectant synthesis, mobilizing carbohydrate energy reserves to promote synthesis of low-molecular-mass osmoprotectants Department of Entomology, Ohio State University, Columbus, OH 43210, USA e-mail: teets.23@osu.edu Y

  10. Hypoxylon mammatum toxins: possible involvement in canker development on aspen

    E-Print Network [OSTI]

    Boyer, Edmond

    Hypoxylon mammatum toxins: possible involvement in canker development on aspen I. Genetet1 J. Pinon a stem canker on aspen (Populus tremula) and on some poplars of the Taca- hamaca section (Pinon, 1976 inhibited callus formation in wounds on aspen bark. Schipper (1978) and Ster- mer et aL, (1984) confirmed

  11. Mechanism of heterogeneous catalytic reactions involving molecular hydrogen

    SciTech Connect (OSTI)

    Golodets, G.I.

    1987-07-01T23:59:59.000Z

    By means of various physicochemical methods, including kinetics, the mechanism of a series of reactions involving molecular H/sub 2/ (the hydrogenation of carbonyl compounds, nitriles, carbon monoxide, molecular nitrogen, and oxygen) on metallic catalysts of different chemical compositions and degrees of dispersion has been investigated. Some general laws for reactions of this class are formulated.

  12. Argonne National Laboratory has been actively involved in the development

    E-Print Network [OSTI]

    Kemner, Ken

    Argonne National Laboratory has been actively involved in the development of advanced batteries at Argonne and named it the National Battery Test Laboratory (NBTL), for the purpose of conducting in these early days of the battery program, Argonne was internationally respected for its advanced battery work

  13. LESSONS LEARNED FROM AN IMPOUNDMENT SLOPE FAILURE INVOLVING GEOSYNTHETICS

    E-Print Network [OSTI]

    failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment. KEYWORDS: Geosynthetic clay liners, Interface Shear Strength, Waste containment, Strength, Stability to illustrate the importance of (i) properly storing geosynthetic clay liners (GCLs) to reduce the amount

  14. On some arithmetic properties of polynomial expressions involving Stirling numbers

    E-Print Network [OSTI]

    Klazar, Martin

    On some arithmetic properties of polynomial expressions involving Stirling numbers of the second by the grant SEP-CONACYT 37259-E. 1 #12;Abstract Let S(n, k) be the classical Stirling numbers of the second. We give similar but more particular results on the more general Stirling-like numbers T(n, k). 2 #12

  15. DEVELOPMENT AND USE OF A DIRECTORY OF ACCIDENT DATABASES INVOLVING

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    DEVELOPMENT AND USE OF A DIRECTORY OF ACCIDENT DATABASES INVOLVING CHEMICALS J.P.Pineau Institut from end-users of accident data who need validated data for dealing with risk assessment in which Data collection Data analysis, Reliability, Uncertainty, Accident, Hazardous material, Risk analysis

  16. "The Greek community will strive for excellence in scholarship, service, leadership, involvement, diversity, building community, and brotherhood/sisterhood."

    E-Print Network [OSTI]

    Linhardt, Robert J.

    fully support our project. As a model for chapter house budgeting and house operation, as well 1255 students) are leading the sustainability effort on campus with their Green Greeks vision and plan involved in class projects and coursework, and increase the sustainability of the Rensselaer community

  17. Chlorophyll antenna size adjustments by irradiance in Dunaliella salina involve coordinate regulation of chlorophyll a oxygenase (CAO)

    E-Print Network [OSTI]

    Chlorophyll antenna size adjustments by irradiance in Dunaliella salina involve coordinate and that of the Lhcb genes in the model organism Dunaliella salina. Among the chlorophyll biosynthesis enzymes tested are a dynamic compensation response (Melis, 1996; 1998). When HL-acclimated cells of D. salina were shifted

  18. analytical system involving: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Analytics. Desired: Successful completion of graduate courses in general linear models or statistical quality control Shepp, Larry 3 Analytic reconstruction of some...

  19. Get Involved with Home Energy Score | Department of Energy

    Energy Savers [EERE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directed offOCHCO2: FinalOffers3.pdf0-45.pdf0 Budget FossilGeothermalGeothermal developersGet Involved with

  20. NEPA-Related Public Involvement | Department of Energy

    Energy Savers [EERE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directed offOCHCO2:Introduction toManagement of theTechno-economicOctober 2013NEPA-Related Public Involvement

  1. Get Involved with Home Energy Score | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onYouTube YouTube Note: Since the.pdf Flash2006-52.pdf0.pdfDepartmentCounsel LawDemonstrationDepartmentGet Involved with

  2. Report on International Collaboration Involving the FE Heater and HG-A Tests at Mont Terri

    SciTech Connect (OSTI)

    Houseworth, Jim; Rutqvist, Jonny; Asahina, Daisuke; Chen, Fei; Vilarrasa, Victor; Liu, Hui-Hai; Birkholzer, Jens

    2013-11-06T23:59:59.000Z

    Nuclear waste programs outside of the US have focused on different host rock types for geological disposal of high-level radioactive waste. Several countries, including France, Switzerland, Belgium, and Japan are exploring the possibility of waste disposal in shale and other clay-rich rock that fall within the general classification of argillaceous rock. This rock type is also of interest for the US program because the US has extensive sedimentary basins containing large deposits of argillaceous rock. LBNL, as part of the DOE-NE Used Fuel Disposition Campaign, is collaborating on some of the underground research laboratory (URL) activities at the Mont Terri URL near Saint-Ursanne, Switzerland. The Mont Terri project, which began in 1995, has developed a URL at a depth of about 300 m in a stiff clay formation called the Opalinus Clay. Our current collaboration efforts include two test modeling activities for the FE heater test and the HG-A leak-off test. This report documents results concerning our current modeling of these field tests. The overall objectives of these activities include an improved understanding of and advanced relevant modeling capabilities for EDZ evolution in clay repositories and the associated coupled processes, and to develop a technical basis for the maximum allowable temperature for a clay repository. The R&D activities documented in this report are part of the work package of natural system evaluation and tool development that directly supports the following Used Fuel Disposition Campaign (UFDC) objectives: ? Develop a fundamental understanding of disposal-system performance in a range of environments for potential wastes that could arise from future nuclear-fuel-cycle alternatives through theory, simulation, testing, and experimentation. ? Develop a computational modeling capability for the performance of storage and disposal options for a range of fuel-cycle alternatives, evolving from generic models to more robust models of performance assessment. For the purpose of validating modeling capabilities for thermal-hydro-mechanical (THM) processes, we developed a suite of simulation models for the planned full-scale FE Experiment to be conducted in the Mont Terri URL, including a full three-dimensional model that will be used for direct comparison to experimental data once available. We performed for the first time a THM analysis involving the Barcelona Basic Model (BBM) in a full three-dimensional field setting for modeling the geomechanical behavior of the buffer material and its interaction with the argillaceous host rock. We have simulated a well defined benchmark that will be used for codeto- code verification against modeling results from other international modeling teams. The analysis highlights the complex coupled geomechanical behavior in the buffer and its interaction with the surrounding rock and the importance of a well characterized buffer material in terms of THM properties. A new geomechanical fracture-damage model, TOUGH-RBSN, was applied to investigate damage behavior in the ongoing HG-A test at Mont Terri URL. Two model modifications have been implemented so that the Rigid-Body-Spring-Network (RBSN) model can be used for analysis of fracturing around the HG-A microtunnel. These modifications are (1) a methodology to compute fracture generation under compressive stress conditions and (2) a method to represent anisotropic elastic and strength properties. The method for computing fracture generation under compressive load produces results that roughly follow trends expected for homogeneous and layered systems. Anisotropic properties for the bulk rock were represented in the RBSN model using layered heterogeneity and gave bulk material responses in line with expectations. These model improvements were implemented for an initial model of fracture damage at the HG-A test. While the HG-A test model results show some similarities with the test observations, differences between the model results and observations remain.

  3. Involvement of purinergic system in inflammation and toxicity induced by copper in zebrafish larvae

    SciTech Connect (OSTI)

    Leite, Carlos Eduardo, E-mail: carlos.leite@pucrs.br [Instituto de Toxicologia e Farmacologia, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, CEP 90619-900 (Brazil); Programa de Pós-Graduação em Medicina: Ciências Médicas, Universidade Federal do Rio Grande do Sul, Porto Alegre, CEP 90035-003 (Brazil); Maboni, Lucas de Oliveira [Instituto de Toxicologia e Farmacologia, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, CEP 90619-900 (Brazil); Faculdade de Biociências, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, CEP 90619-900 (Brazil); Cruz, Fernanda Fernandes [Instituto de Toxicologia e Farmacologia, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, CEP 90619-900 (Brazil); Faculdade de Farmácia, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, CEP 90619-900 (Brazil); Rosemberg, Denis Broock [Programa de Pós-graduação em Ciências Ambientais, Universidade Comunitária da Região de Chapecó, Chapecó, CEP 89809-000 (Brazil); and others

    2013-11-01T23:59:59.000Z

    The use of zebrafish (Danio rerio) is increasing as an intermediate preclinical model, to prioritize drug candidates for mammalian testing. As the immune system of the zebrafish is quite similar to that of mammals, models of inflammation are being developed for the screening of new drugs. The characterization of these models is crucial for studies that seek for mechanisms of action and specific pharmacological targets. It is well known that copper is a metal that induces damage and cell migration to hair cells of lateral line of zebrafish. Extracellular nucleotides/nucleosides, as ATP and adenosine (ADO), act as endogenous signaling molecules during tissue damage by exerting effects on inflammatory and immune responses. The present study aimed to characterize the inflammatory status, and to investigate the involvement of the purinergic system in copper-induced inflammation in zebrafish larvae. Fishes of 7 days post-fertilization were exposed to 10 ?M of copper for a period of 24 h. The grade of oxidative stress, inflammatory status, copper uptake, the activity and the gene expression of the enzymes responsible for controlling the levels of nucleotides and adenosine were evaluated. Due to the copper accumulation in zebrafish larvae tissues, the damage and oxidative stress were exacerbated over time, resulting in an inflammatory process involving IL-1?, TNF-?, COX-2 and PGE{sub 2}. Within the purinergic system, the mechanisms that control the ADO levels were the most involved, mainly the reactions performed by the isoenzyme ADA 2. In conclusion, our data shed new lights on the mechanisms related to copper-induced inflammation in zebrafish larvae. - Graphical abstract: This scheme provides a chronological proposition for the biochemical events induced by copper in zebrafish larvae. The dashed line shows the absorption of copper over the exposure time. After 1 h of exposure to copper, the release of PGE{sub 2} occurs, followed by an increase of MPO (as a consequence of neutrophil migration), increased expression of genes involved in inflammatory events (IL-1? and TNF-?) and, reduction of the anti-inflammatory cytokine IL-10 at 4 h. At 24 h, the copper concentration is found highly increased, what is coincident with oxidative stress. Regarding the purinergic system, it is possible to observe an inhibition of ecto-5?-NT and ADA, with the consequent increase of AMP and ADA, respectively, at 24 h. The expression of enzyme-related genes shows a decrease in the expression of ecto-5?-NT and variable expressions of ADA subfamily enzymes. - Highlights: • Copper led to increased oxidative stress, and decreased the antioxidants' defenses. • Copper induced time-related changes of IL-1?, TNF-?, IL-10 and PGE{sub 2} levels. • ADA activity controls the levels of adenosine in copper-induced inflammation. • ADA 2 is the main ADA subfamily involved. • The purinergic system seems to be involved in the resolution of inflammation.

  4. An external dose reconstruction involving a radiological dispersal device

    E-Print Network [OSTI]

    Hearnsberger, David Wayne

    2007-04-25T23:59:59.000Z

    phantom compared favorably to the derived organ absorbed doses measured by the Panasonic thermoluminescence dosimeters and with Monte Carlo �N� Particle modeled results. Additionally, a Victoreen 450P pressurized ion chamber measured...

  5. Cache Probabilistic Modeling for Basic Sparse Algebra Kernels involving Matrices with a Non Uniform Distribution

    E-Print Network [OSTI]

    Fraguela, Basilio B.

    ´ia (CICYT) under project TIC96-1125, Xunta de Galicia under Project XUGA20605B96 p pp ppp ppp ppp pp p pp ppp p ppp pppppp ppp pppppp pp p pp ppp p ppp pppppp ppp pppppp pp p pp ppp p pppppp ppp pppppp ppp pp ppp p pp p pppppp ppp pppppp ppp pp ppp p pp p pppppp ppp pppppp ppp pp p pp p pp p ppp ppp ppp ppp

  6. A Role-involved Conditional Purpose-based Access Control Model

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    control to achieve database security and available in database management systems. The structure helps. Access control is the process of limiting access to the re- sources of a system only to authorized users a secure privacy policy to remove the fear of customers. Thus in an internal management system, a reliable

  7. Optical model potentials involving loosely bound p-shell nuclei around 10 MeV/nucleon

    E-Print Network [OSTI]

    Trache, L.; Azhari, A.; Clark, HL; Gagliardi, Carl A.; Lui, YW; Mukhamedzhanov, AM; Tribble, Robert E.; Carstoiu, F.

    2000-01-01T23:59:59.000Z

    .86 1.07 0.7 4 241.36 37.45 0.82 1.06 0.7 5 306.44 39.14 0.81 1.05 0.6 13C (130 MeV)19Be 1 94.2 20.9 0.77 0.99 0.8 2 164.2 23.0 0.67 0.98 0.8 3 226.7 31.9 0.62 0.90 0.8 7Li (63 MeV)19Be 1 134.4 19.82 0.54 1.03 0.9 2 221.6 27.33 0.54 0.92 0.8 3... 276.5 37.3 0.61 0.81 0.7 7Li (63 MeV)113C 1 54.3 29.9 0.92 1.03 0.7 2 99.8 22.0 0.77 1.01 0.8 3 154.8 22.7 0.76 1.00 0.7 4 244.6 26.4 0.68 0.96 0.7 7Li (130 MeV)19Be 1 60.0 17.71 0.86 1.07 0.6 2 129.4 30.7 0.57 0.80 0.9 7Li (130 MeV)113C 1 123...

  8. COMPASS Hadron Spectroscopy -- Final states involving neutrals and kaons

    E-Print Network [OSTI]

    Frank Nerling; for the COMPASS collaboration

    2010-09-11T23:59:59.000Z

    The COMPASS experiment at CERN is well designed for light-hadron spectroscopy with emphasis on the detection of new states, in particular the search for $J^{PC}$-exotic states and glueballs. We have collected data with 190 GeV/c charged hadron beams on a liquid hydrogen and nuclear targets in 2008/09. The spectrometer features good coverage by electromagnetic calorimetry and a RICH detector further provides $\\pi$ / $K$ separation, allowing for studying final states involving neutral particles like $\\pi^0$ or $\\eta$ as well as hidden strangeness, respectively. We discuss the status of ongoing analyses with specific focus on diffractively produced $(\\pi^0\\pi^0\\pi)^{-}$ as well as $(K\\bar{K}\\pi)^{-}$ final states.

  9. A sensitivity analysis of the treatment of wind energy in the AEO99 version of NEMS

    E-Print Network [OSTI]

    Osborn, Julie G.; Wood, Frances; Richey, Cooper; Sanders, Sandy; Short, Walter; Koomey, Jonathan

    2001-01-01T23:59:59.000Z

    Administration. 1998. Annual Energy Outlook 1999: WithDepartment of Energy’s Annual Energy Outlook (AEO) forecastDepartment of Energy’s Annual Energy Outlook 1999 (AEO99)

  10. Ženski pari moških poimenovanj v slovenskem knjižnem jeziku 16. stoletja

    E-Print Network [OSTI]

    Merše, Majda

    2008-02-01T23:59:59.000Z

    , inu Neverni zhlovik dobre priatele smoti (DB 1584: II, 164a) – Denn ein zorniger Mensch zündet hadder an / vnd der Gottlose verwirret gute Freunde (LB 1545: 1791). 1.1.4 Med parnimi izsamostalniškimi tvorjenkami so tudi take, ki ozna?u- jejo...

  11. Review: Besedotvorni tematski blok na petnajstem mednarodnem slvisti?nem kongresu v Minsku (2013)

    E-Print Network [OSTI]

    Vorši?, Ines; Breznik, Irena Stramlji?

    2014-06-26T23:59:59.000Z

    — #20;#19;#28; — 2FHQH#15;#3;]DSLVNL#15;#3;SRURþLOD#3;±#3;5HYLHZV#15;#3;1RWHV#15;#3;5HSRUWV Y#3; HNVSUHVLRQLVWLþQR#3; VWLOQR#3; SDUDGLJPR#3; #11;#20;#28;#20;#23;±#20;#28;#21;#22;#12;#3;RSUDYLOD#3;L]MHPQR#3;]DKWHYQR#3; LQ#3; REVHåQR#3;GHOR#17;#3...;8VSHOR#3; ML#3; MH#3; ]DSROQLWL#3; YU]HO#3;PHG#3;HNVSUHVLRQLVWLþQR#3;SRH]LMR#3; LQ#3; GUDPDWLNR#15;#3; GR#3; VHGDM#3; EROM#3; UD]LVNDQLPD#3; SRGURþMHPD#17;#3; âWXGLMH#3; V#3; SRGURþMD#3;PHWD-­ IRULNH#3;]JRGQMH#3;HNVSUHVLRQLVWLþQH#3;NUDWNH#3; SUR]H#3;XYUãþ...

  12. Frequency Stabilization in Non-linear MEMS and NEMS Oscillators (IN-11-087)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville Power AdministrationField8,Dist.Newof Energy Forrestal NT oFF DepaPhysics Lab- Energy

  13. EIA model documentation: Documentation of the Oil and Gas Supply Module (OGSM)

    SciTech Connect (OSTI)

    NONE

    1997-01-01T23:59:59.000Z

    The purpose of this report is to define the objectives of the Oil and Gas Supply Model (OGSM), to describe the model`s basic approach, and to provide detail on how the model works. This report is intended as a reference document for model analysts, users, and the public. Projected production estimates of US crude oil and natural gas are based on supply functions generated endogenously within National Energy Modeling System (NEMS) by the OGSM. OGSM encompasses domestic crude oil and natural gas supply by both conventional and nonconventional recovery techniques. Nonconventional recovery includes enhanced oil recovery (EOR), and unconventional gas recovery (UGR) from tight gas formations, Devonian shale and coalbeds. Crude oil and natural gas projects are further disaggregated by geographic region. OGSM projects US domestic oil and gas supply for six Lower 48 onshore regions, three offshore regions, and Alaska. The general methodology relies on forecasted drilling expenditures and average drilling costs to determine exploratory and developmental drilling levels for each region and fuel type. These projected drilling levels translate into reserve additions, as well as a modification of the production capacity for each region. OGSM also represents foreign trade in natural gas, imports and exports by entry region.

  14. Renewable Energy and Efficiency Modeling Analysis Partnership: An Analysis of How Different Energy Models Addressed a Common High Renewable Energy Penetration Scenario in 2025

    E-Print Network [OSTI]

    Blair, N.

    2010-01-01T23:59:59.000Z

    taken from EIA’s Annual Energy Outlook (AEO), 20% windon Renewable Energy Annual Energy Outlook Argonne NationalNEMS for the 2006 Annual Energy Outlook (AEO). (Note: The

  15. Personnel involved in nuclear standards development: 1980 directory

    SciTech Connect (OSTI)

    Carr, S.J. (ed.)

    1980-03-01T23:59:59.000Z

    The development of nuclear standards is an active and necessary endeavor that is concerned with the safe, orderly, and economic development of nuclear potential. There are almost 4100 people from the teachnical community who are presently involved either in writing nuclear standards, including codes, or in the management and processing roles necessary for their approval and promulgation. This document identifies the current participation of each individual as member, chairman, cochairman (vice-chairman), or secretary of about 700 standards development committees and groups. The standards committees and groups are identified with the organizations that are responsible for the preparation, review, and maintenance of the standards and that provide support through supervisory committees and headquarters staff. This directory includes four major sections: personnel, employers, committees, and a Key-Word-in-Context (KWIC) Index of committee titles. It can also be used to identify the participation of employers as well as to recognize the contributions of individuals to the often interdisciplinary activity of standards development.

  16. Representation of analysis results involving aleatory and epistemic uncertainty.

    SciTech Connect (OSTI)

    Johnson, Jay Dean (ProStat, Mesa, AZ); Helton, Jon Craig (Arizona State University, Tempe, AZ); Oberkampf, William Louis; Sallaberry, Cedric J.

    2008-08-01T23:59:59.000Z

    Procedures are described for the representation of results in analyses that involve both aleatory uncertainty and epistemic uncertainty, with aleatory uncertainty deriving from an inherent randomness in the behavior of the system under study and epistemic uncertainty deriving from a lack of knowledge about the appropriate values to use for quantities that are assumed to have fixed but poorly known values in the context of a specific study. Aleatory uncertainty is usually represented with probability and leads to cumulative distribution functions (CDFs) or complementary cumulative distribution functions (CCDFs) for analysis results of interest. Several mathematical structures are available for the representation of epistemic uncertainty, including interval analysis, possibility theory, evidence theory and probability theory. In the presence of epistemic uncertainty, there is not a single CDF or CCDF for a given analysis result. Rather, there is a family of CDFs and a corresponding family of CCDFs that derive from epistemic uncertainty and have an uncertainty structure that derives from the particular uncertainty structure (i.e., interval analysis, possibility theory, evidence theory, probability theory) used to represent epistemic uncertainty. Graphical formats for the representation of epistemic uncertainty in families of CDFs and CCDFs are investigated and presented for the indicated characterizations of epistemic uncertainty.

  17. Model Wind Ordinance for Local Governments

    Broader source: Energy.gov [DOE]

    In 2006, Pennsylvania developed a model local ordinance for wind energy facilities through a collaborative effort involving several state departments and stakeholder groups. The purpose of the...

  18. Governance, participation and avoidance: everyday public involvement in the Scottish NHS 

    E-Print Network [OSTI]

    Stewart, Ellen Anderson

    2012-06-29T23:59:59.000Z

    Public involvement in health services is an area of policy where ostensibly good intentions appear to repeatedly fail in implementation. Since the late 1990s public involvement in the UK NHS has been subject to frequent ...

  19. Involvement of Shewanella oneidensis MR-1 LuxS in Biofilm Development...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Involvement of Shewanella oneidensis MR-1 LuxS in Biofilm Development and Sulfur Metabolism. Involvement of Shewanella oneidensis MR-1 LuxS in Biofilm Development and Sulfur...

  20. Application of Dissolution Dynamic Nuclear Polarization to the Characterization of Reactions Involving Large Molecules

    E-Print Network [OSTI]

    Lee, Youngbok

    2013-03-13T23:59:59.000Z

    aims to extend the applicability of D-DNP into new areas of chemistry, which involve the characterization of interactions and reactions involving large molecules. In a first project, fluorine hyperpolarization is exploited to investigate protein...

  1. OSPREY Model

    SciTech Connect (OSTI)

    Veronica J. Rutledge

    2013-01-01T23:59:59.000Z

    The absence of industrial scale nuclear fuel reprocessing in the U.S. has precluded the necessary driver for developing the advanced simulation capability now prevalent in so many other countries. Thus, it is essential to model complex series of unit operations to simulate, understand, and predict inherent transient behavior and feedback loops. A capability of accurately simulating the dynamic behavior of advanced fuel cycle separation processes will provide substantial cost savings and many technical benefits. The specific fuel cycle separation process discussed in this report is the off-gas treatment system. The off-gas separation consists of a series of scrubbers and adsorption beds to capture constituents of interest. Dynamic models are being developed to simulate each unit operation involved so each unit operation can be used as a stand-alone model and in series with multiple others. Currently, an adsorption model has been developed within Multi-physics Object Oriented Simulation Environment (MOOSE) developed at the Idaho National Laboratory (INL). Off-gas Separation and REcoverY (OSPREY) models the adsorption of off-gas constituents for dispersed plug flow in a packed bed under non-isothermal and non-isobaric conditions. Inputs to the model include gas, sorbent, and column properties, equilibrium and kinetic data, and inlet conditions. The simulation outputs component concentrations along the column length as a function of time from which breakthrough data is obtained. The breakthrough data can be used to determine bed capacity, which in turn can be used to size columns. It also outputs temperature along the column length as a function of time and pressure drop along the column length. Experimental data and parameters were input into the adsorption model to develop models specific for krypton adsorption. The same can be done for iodine, xenon, and tritium. The model will be validated with experimental breakthrough curves. Customers will be given access to OSPREY to used and evaluate the model.

  2. Panel - Generic Longitudinal Business Process Model

    E-Print Network [OSTI]

    Barkow, Ingo; Block, William C.; Greenfield, Jay; Hebing, Marcel; Hoyle, Larry; Thomas, Wendy

    2013-04-03T23:59:59.000Z

    This presentation described a model for the processes involved in a longitudinal study. The model was developed at a symposium-style workshop held at Dagstuhl in September of 2011 (http://www.dagstuhl.de/11382). The Generic Longitudinal Business...

  3. EPRI Cogeneration Models -- DEUS and COPE 

    E-Print Network [OSTI]

    Mauro, R.; Hu, S. D.

    1983-01-01T23:59:59.000Z

    portion of the study involved the development of a simulation model for evaluation of cogeneration systems on a site specific basis. Dual Energy Use Systems (DEUS) model contains an extensive data base with which to cost and size many different...

  4. EIA - Annual Energy Outlook (AEO) 2011 Data Tables

    Annual Energy Outlook 2013 [U.S. Energy Information Administration (EIA)]

    75. Imported Liquids by Source XLS Table 76. Conversion Factors XLS About the Annual Energy Outlook Contact Information and Staff About the National Energy Modeling System (NEMS)...

  5. Modeling Message Blocking and Deadlock in Interconnection Networks

    E-Print Network [OSTI]

    Pinkston, Timothy M.

    Modeling Message Blocking and Deadlock in Interconnection Networks Sugath Warnakulasuriya. This model allows various types of message blocking to be represented precisely, including deadlock. Our model of deadlock distinguishes between messages involved in deadlock and those simply dependent

  6. Simple ocean carbon cycle models

    SciTech Connect (OSTI)

    Caldeira, K. [Lawrence Livermore National Lab., CA (United States); Hoffert, M.I. [New York Univ., NY (United States). Dept. of Earth System Sciences; Siegenthaler, U. [Bern Univ. (Switzerland). Inst. fuer Physik

    1994-02-01T23:59:59.000Z

    Simple ocean carbon cycle models can be used to calculate the rate at which the oceans are likely to absorb CO{sub 2} from the atmosphere. For problems involving steady-state ocean circulation, well calibrated ocean models produce results that are very similar to results obtained using general circulation models. Hence, simple ocean carbon cycle models may be appropriate for use in studies in which the time or expense of running large scale general circulation models would be prohibitive. Simple ocean models have the advantage of being based on a small number of explicit assumptions. The simplicity of these ocean models facilitates the understanding of model results.

  7. The effects of school gardening on parent involvement in elementary schools

    E-Print Network [OSTI]

    Boyer, Roxanne Christina

    2002-01-01T23:59:59.000Z

    to helping with schoolwork at home (Henderson et al. , 1986). Some researchers divide types of involvement according to where it occurs such as in the home?school, or community (NCES, 1997). Others define parent involvement according to how... in parenting, communicating, volunteering, learning at home, decision making, and collaborating with the community (Epstein, 1995). Henderson and others (1986) define parent involvement in terms of the roles that parents have in education such as partners...

  8. Elementary Act of Consciousness or Cycle of Mind, involving Distant and Nonlocal Interaction

    E-Print Network [OSTI]

    Alex Kaivarainen

    2007-09-11T23:59:59.000Z

    Each macroscopic process can be subdivided on the quantum and classical stages. Particularly, the quantum stages of Cycle of Mind involves:1) the stimulation of dynamic correlation between water clusters in the same and remote microtubules (MTs) in state of mesoscopic Bose condensation (mBC) by phonons (acoustic waves) and by librational IR photons (electromagnetic-EM waves) distant exchange; 2) the transition from distant EM interaction between remote MTs to nonlocal quantum interaction, induced by IR photons exchange between clusters, the clusters Virtual Replicas multiplication (VRM) and virtual guides (VirG) formation between elementary particles of remote coherent water molecules. This process represents transition from mesoscopic Bose condensation to macroscopic nonuniform semi-virtual Bose condensation (VirBC) (Kaivarainen, 2006, http://arxiv.org/abs/physics/0207027); 3) the collapsing of corresponding macroscopic wave function, as a result of the optical bistability of the entangled water clusters and their disassembly due to librational photons pumping, shifting clusters to less stable state; 4) turning the clusterphilic interaction between water clusters in the open state of cavities between alpha and beta tubulins to hydrophobic one and the in-phase shift of these cavities to the closed state due to clusters disassembly (Kaivarainen, http://arxiv.org/abs/physics/0102086). The classical stages of our Hierarchic model of elementary act of Cycle of Mind are analyzed in detail.

  9. Molecular genetic analysis of activation-tagged transcription factors thought to be involved in photomorphogenesis

    SciTech Connect (OSTI)

    Neff, Michael M.

    2011-06-23T23:59:59.000Z

    This is a final report for Department of Energy Grant No. DE-FG02-08ER15927 entitled “Molecular Genetic Analysis of Activation-Tagged Transcription Factors Thought to be Involved in Photomorphogenesis”. Based on our preliminary photobiological and genetic analysis of the sob1-D mutant, we hypothesized that OBP3 is a transcription factor involved in both phytochrome and cryptochrome-mediated signal transduction. In addition, we hypothesized that OBP3 is involved in auxin signaling and root development. Based on our preliminary photobiological and genetic analysis of the sob2-D mutant, we also hypothesized that a related gene, LEP, is involved in hormone signaling and seedling development.

  10. aopex11-1 gene involved: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  11. antagonist labedipinedilol-a involves: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  12. aeruginosa w51d involves: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  13. analysis involving tvs-m: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  14. acetobutylicum involving non-coding: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  15. arene di-oxygenases involved: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    GEOSYNTHETICS Engineering Websites Summary: failure involving a reinforced geosynthetic clay liner in a sedimentation pond at a waste containment liners to hydrate during on-site...

  16. A Tomato Detached Leaf Assay for Chemical Genomics of an HLB Model System

    E-Print Network [OSTI]

    Patne, S.; Eulgem, T.; Roose, M. L.

    2014-01-01T23:59:59.000Z

    Leaf Assay for Chemical Genomics of an HLB Model Systemapproach known as chemical genomics with Tomato “Psyllida model of HLB. Chemical genomics involves three key stages

  17. Customer Involvement

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville Power Administration would likeConstitution4Customer-Comments Sign In About | Careers |

  18. Getting Involved

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Science (SC) Environmental AssessmentsGeoffrey

  19. Unravelling aspects of the gas phase chemistry involved in diamond chemical vapour deposition

    E-Print Network [OSTI]

    Bristol, University of

    of thin Ðlms of polycrystalline diamond by chemi- cal vapour deposition (CVD) methods,2h4 since which timeUnravelling aspects of the gas phase chemistry involved in diamond chemical vapour deposition been used to unravel details of the gas phase chemistry involved in diamond chemical vapour deposition

  20. Involving Geospatial Information in the Analysis of Land-Cover Change along the Tanzania Coast

    E-Print Network [OSTI]

    Wang, Y.Q. "Yeqiao"

    Involving Geospatial Information in the Analysis of Land-Cover Change along the Tanzania Coast.1080/08920750590883132 Involving Geospatial Information in the Analysis of Land-Cover Change along the Tanzania Coast YEQIAO WANG and the area of woodland interspersed with agriculture increased. This study demonstrates how geospatial

  1. New Developments involving the Stream Health Index for the Puget Sound Lowland

    E-Print Network [OSTI]

    Washington at Seattle, University of

    New Developments involving the Stream Health Index for the Puget Sound Lowland Grace Chiu Peter and ecological sciences. #12;#12;Full title: New Developments involving the Stream Health Index for the Puget;SUMMARY Since the introduction of the stream health index for the Puget Sound Lowland (SHIPSL) (Chiu

  2. ORIGINAL PAPER On the Role of the Difference in Surface Tensions Involved

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    ORIGINAL PAPER On the Role of the Difference in Surface Tensions Involved in the Allosteric was to develop the relationship between membrane surface tension, and the allosteric balance in a difference in surface tensions that is involved in the creation of a reservoir of intracellular vesicles

  3. Connecting models to the real world : game theory in action

    E-Print Network [OSTI]

    Alexandrova, Anna

    2006-01-01T23:59:59.000Z

    and Inference in Econometric Models: Festschrift in Honor ofthat involve econometric testing and experimentation. Casualand methods of statistical and econometric analysis, and the

  4. Dosimetric and Clinical Outcomes of Involved-Field Intensity-Modulated Radiotherapy After Chemotherapy for Early-Stage Hodgkin's Lymphoma With Mediastinal Involvement

    SciTech Connect (OSTI)

    Lu Ningning [Department of Radiation Oncology, Cancer Hospital, National Cancer Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (China)] [Department of Radiation Oncology, Cancer Hospital, National Cancer Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (China); Li Yexiong, E-mail: yexiong@yahoo.com [Department of Radiation Oncology, Cancer Hospital, National Cancer Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (China); Wu Runye; Zhang Ximei; Wang Weihu; Jin Jing; Song Yongwen; Fang Hui; Ren Hua; Wang Shulian; Liu Yueping; Liu Xinfan; Chen Bo; Dai Jianrong; Yu Zihao [Department of Radiation Oncology, Cancer Hospital, National Cancer Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (China)] [Department of Radiation Oncology, Cancer Hospital, National Cancer Center, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing (China)

    2012-09-01T23:59:59.000Z

    Purpose: To evaluate the dosimetric and clinical outcomes of involved-field intensity-modulated radiotherapy (IF-IMRT) for patients with early-stage Hodgkin's lymphoma (HL) with mediastinal involvement. Methods and Materials: Fifty-two patients with early-stage HL that involved the mediastinum were reviewed. Eight patients had Stage I disease, and 44 patients had Stage II disease. Twenty-three patients (44%) presented with a bulky mediastinum, whereas 42 patients (81%) had involvement of both the mediastinum and either cervical or axillary nodes. All patients received combination chemotherapy followed by IF-IMRT. The prescribed radiation dose was 30-40 Gy. The dose-volume histograms of the target volume and critical normal structures were evaluated. Results: The median mean dose to the primary involved regions (planning target volume, PTV1) and boost area (PTV2) was 37.5 Gy and 42.1 Gy, respectively. Only 0.4% and 1.3% of the PTV1 and 0.1% and 0.5% of the PTV2 received less than 90% and 95% of the prescribed dose, indicating excellent PTV coverage. The median mean lung dose and V20 to the lungs were 13.8 Gy and 25.9%, respectively. The 3-year overall survival, local control, and progression-free survival rates were 100%, 97.9%, and 96%, respectively. No Grade 4 or 5 acute or late toxicities were reported. Conclusions: Despite the large target volume, IF-IMRT gave excellent dose coverage and a favorable prognosis, with mild toxicity in patients with early-stage mediastinal HL.

  5. Involvement of the transcription factor FoxM1 in contact inhibition

    SciTech Connect (OSTI)

    Faust, Dagmar; Al-Butmeh, Firas; Linz, Berenike [Institute of Toxicology, Medical Center of the Johannes Gutenberg-University, Obere Zahlbacherstr. 67, 55131 Mainz (Germany)] [Institute of Toxicology, Medical Center of the Johannes Gutenberg-University, Obere Zahlbacherstr. 67, 55131 Mainz (Germany); Dietrich, Cornelia, E-mail: cdietric@uni-mainz.de [Institute of Toxicology, Medical Center of the Johannes Gutenberg-University, Obere Zahlbacherstr. 67, 55131 Mainz (Germany)] [Institute of Toxicology, Medical Center of the Johannes Gutenberg-University, Obere Zahlbacherstr. 67, 55131 Mainz (Germany)

    2012-10-05T23:59:59.000Z

    Highlights: Black-Right-Pointing-Pointer The transcription factor FoxM1 is downregulated upon contact inhibition. Black-Right-Pointing-Pointer The decrease in FoxM1 levels occurs very likely due to inhibition of ERK activity. Black-Right-Pointing-Pointer The decrease in FoxM1 is not sufficient, but required for contact inhibition. Black-Right-Pointing-Pointer We propose a new model of contact inhibition involving pRB/E2F and FoxM1. -- Abstract: Contact inhibition is a crucial mechanism regulating proliferation in vitro and in vivo. Although it is generally accepted that contact inhibition plays a pivotal role in maintaining tissue homeostasis, the molecular mechanisms of contact inhibition are still not fully understood. FoxM1 is known as a proliferation-associated transcription factor and is upregulated in many cancer types. Vice versa, anti-proliferative signals, such as TGF-{beta} and differentiation signals decrease FoxM1 expression. Here we investigated the role of FoxM1 in contact inhibition in fibroblasts. We show that protein expression of FoxM1 is severely and rapidly downregulated upon contact inhibition, probably by inhibition of ERK activity, which then leads to decreased expression of cyclin A and polo-like kinase 1. Vice versa, ectopic expression of FoxM1 prevents the decrease in cyclin A and polo-like kinase 1 and causes a two-fold increase in saturation density indicating loss of contact inhibition. Hence, we show that downregulation of FoxM1 is required for contact inhibition by regulating expression of cyclin A and polo-like kinase 1.

  6. Issues Involving The OSI Concept of Operation For Noble Gas Radionuclide Detection

    SciTech Connect (OSTI)

    Carrigan, C R; Sun, Y

    2011-01-21T23:59:59.000Z

    The development of a technically sound protocol for detecting the subsurface release of noble gas radionuclides is critical to the successful operation of an on site inspection (OSI) under the CTBT and has broad ramifications for all aspects of the OSI regime including the setting of specifications for both sampling and analysis equipment used during an OSI. With NA-24 support, we are investigating a variety of issues and concerns that have significant bearing on policy development and technical guidance regarding the detection of noble gases and the creation of a technically justifiable OSI concept of operation. The work at LLNL focuses on optimizing the ability to capture radioactive noble gases subject to the constraints of possible OSI scenarios. This focus results from recognizing the difficulty of detecting gas releases in geologic environments - a lesson we learned previously from the LLNL Non-Proliferation Experiment (NPE). Evaluation of a number of important noble gas detection issues, potentially affecting OSI policy, has awaited the US re-engagement with the OSI technical community. Thus, there have been numerous issues to address during the past 18 months. Most of our evaluations of a sampling or transport issue necessarily involve computer simulations. This is partly due to the lack of OSI-relevant field data, such as that provided by the NPE, and partly a result of the ability of LLNL computer-based models to test a range of geologic and atmospheric scenarios far beyond what could ever be studied in the field making this approach very highly cost effective. We review some highlights of the transport and sampling issues we have investigated during the past year. We complete the discussion of these issues with a description of a preliminary design for subsurface sampling that is intended to be a practical solution to most if not all the challenges addressed here.

  7. Ranacyclins, a New Family of Short Cyclic Antimicrobial Peptides: Biological Function, Mode of Action, and Parameters Involved in Target Specificity,,@

    E-Print Network [OSTI]

    Pompeu Fabra, Universitat

    of Action, and Parameters Involved in Target Specificity,,@ M. Luisa Mangoni, Niv Papo,§ Giuseppina Mignogna

  8. The role of involvement and commitment in explaining intention to engage in birding trips

    E-Print Network [OSTI]

    Kim, Seong-Seop

    1996-01-01T23:59:59.000Z

    -psychological involvement measures, and measures of commitment; (c) to ascertain how well Laurent and Kapferer's (1985) scale, Zaichkowsky's (1985) scale, a set of behavioral measures, and commitment nimures explain intention to go on birding trips; (4) to conceptualize...

  9. A study of parental involvement and school climate: Perspective from the middle school

    E-Print Network [OSTI]

    Dixon, Shantina Rayford

    2009-05-15T23:59:59.000Z

    This study examines school level differences on different dimensions of teacherrated parent involvement and school climate while adjusting for age, gender, ethnicity, how certified, and number of years teaching. Two hundred twenty-four elementary...

  10. School-Based Family Involvement: Patterns and Predictors in the NLTS2

    E-Print Network [OSTI]

    Frew, Leigh Ann

    2012-10-19T23:59:59.000Z

    This investigation used data from the National Longitudinal Transition Study 2 (NLTS2) to investigate patterns among student, family, and school characteristics, school outreach programs, and school-based family involvement for families of 5...

  11. Examination of offsite radiological emergency protective measures for nuclear reactor accidents involving core melt

    E-Print Network [OSTI]

    Aldrich, David C.

    1979-01-01T23:59:59.000Z

    Evacuation, sheltering followed by population relocation, and iodine prophylaxis are evaluated as offsite public protective measures in response to nuclear reactor accidents involving core-melt. Evaluations were conducted ...

  12. Nucleotide diversity and neutrality testing in genes involved in adaptation in Douglas-fir

    E-Print Network [OSTI]

    Nucleotide diversity and neutrality testing in genes involved in adaptation in Douglas-fir B. Pande-Oregon region, and 684 SNPs were identified in total. We report the estimation of nucleotide diversity and tests

  13. Use of associated polynomials for division involving polynomials over arbitrary fields

    E-Print Network [OSTI]

    Jones, James Edgar

    1968-01-01T23:59:59.000Z

    USE OF ASSOCIATED POLYNOMIALS FOR DIVISION INVOLVING POLYNOMIALS OVER ARBITRARY FIELDS A Thesis by JAMES EDGAR JOiVES Submitted to the Graduate College of the Texas A&M University in partiai fulfillment of the requirements for the degree... of MASTER OF SCIENCE August 1968 Major Subject: MATHEJRTICS USE OF ASSOCIATED POLYNOMIALS FOR DIVISION INVOLVING POLYNOMIALS OVER ARBITRARY FIELDS A Thesis by JAMES EDGAR JONES Approved as to style and content by (Chairman of Committee) (Head...

  14. Modeling Compressed Turbulence

    SciTech Connect (OSTI)

    Israel, Daniel M. [Los Alamos National Laboratory

    2012-07-13T23:59:59.000Z

    From ICE to ICF, the effect of mean compression or expansion is important for predicting the state of the turbulence. When developing combustion models, we would like to know the mix state of the reacting species. This involves density and concentration fluctuations. To date, research has focused on the effect of compression on the turbulent kinetic energy. The current work provides constraints to help development and calibration for models of species mixing effects in compressed turbulence. The Cambon, et al., re-scaling has been extended to buoyancy driven turbulence, including the fluctuating density, concentration, and temperature equations. The new scalings give us helpful constraints for developing and validating RANS turbulence models.

  15. SPE 91413SPE 91413 Anangela Garcia

    E-Print Network [OSTI]

    Mohaghegh, Shahab

    Regional Meeting #12;SPE Eastern Regional Meeting #12;SPE Eastern Regional Meeting Annual Energy Outlook (2025) EIA's National Energy Modeling System (NEMS) Annual Energy Outlook (2025) EIA's National Energy Modeling System (NEMS) Energy Information Administration #12;SPE Eastern Regional Meeting Back propagation

  16. Are Standard Solar Models Reliable?

    E-Print Network [OSTI]

    John N. Bahcall; M. H. Pinsonneault; Sarbani Basu; J. Christensen-Dalsgaard

    1996-12-20T23:59:59.000Z

    The sound speeds of solar models that include element diffusion agree with helioseismological measurements to a rms discrepancy of better than 0.2% throughout almost the entire sun. Models that do not include diffusion, or in which the interior of the sun is assumed to be significantly mixed, are effectively ruled out by helioseismology. Standard solar models predict the measured properties of the sun more accurately than is required for applications involving solar neutrinos.

  17. Kinetic models of opinion formation

    E-Print Network [OSTI]

    G. Toscani

    2006-05-17T23:59:59.000Z

    We introduce and discuss certain kinetic models of (continuous) opinion formation involving both exchange of opinion between individual agents and diffusion of information. We show conditions which ensure that the kinetic model reaches non trivial stationary states in case of lack of diffusion in correspondence of some opinion point. Analytical results are then obtained by considering a suitable asymptotic limit of the model yielding a Fokker-Planck equation for the distribution of opinion among individuals.

  18. Commodity market modeling and physical trading strategies

    E-Print Network [OSTI]

    Ellefsen, Per Einar

    2010-01-01T23:59:59.000Z

    Investment and operational decisions involving commodities are taken based on the forward prices of these commodities. These prices are volatile, and a model of their evolution must correctly account for their volatility ...

  19. Reform of the EIA process in Indonesia: improving the role of public involvement

    SciTech Connect (OSTI)

    Purnama, Dadang

    2003-07-01T23:59:59.000Z

    The implementation of Environmental Impact Assessment (EIA) as a planning tool has been utilised for a relatively long time in Indonesia. It was introduced formally through the Act No. 4/1982. Supporting regulation was established in 1986 when Government Regulation No. 29 was enacted. After developing the EIA system for 14 years, Indonesia finally recognized the importance of emphasizing public involvement in the EIA guidelines of 2000. EIA in the previous Indonesian regulations, i.e. Regulation No. 29/1986 and No. 51/1993, did not have provisions for direct public involvement. The Indonesian Government Regulation No. 27/1999 is currently accommodating the above issue. Guidelines for public announcement and public involvement have been introduced in a decree issued by the Head of Indonesia's Environmental Impact Management Agency No. KepDal 08/2000. This was officially enacted on 7 November 2000 in response to the demand for more public involvement, an issue that was ambiguous in the previous legislation. This paper discusses: the implementation of the new guidelines; what has been achieved; and the challenges during implementation. While the paper focuses its review on the Indonesian EIA system, Indonesia's experience is relevant to many other developing countries that are starting to adopt public involvement in their decision-making processes.

  20. Co-relation of Variables Involved in the Occurrence of Crane Accidents in U.S. through Logit Modeling.

    E-Print Network [OSTI]

    Bains, Amrit Anoop Singh

    2010-10-12T23:59:59.000Z

    One of the primary reasons of the escalating rates of injuries and fatalities in the construction industry is the ever so complex, dynamic and continually changing nature of construction work. Use of cranes has become imperative to overcome...

  1. TOWARD END-TO-END MODELING FOR NUCLEAR EXPLOSION MONITORING: SIMULATION OF UNDERGROUND NUCLEAR EXPLOSIONS AND EARTHQUAKES USING HYDRODYNAMIC AND ANELASTIC SIMULATIONS, HIGH-PERFORMANCE COMPUTING AND THREE-DIMENSIONAL EARTH MODELS

    SciTech Connect (OSTI)

    Rodgers, A; Vorobiev, O; Petersson, A; Sjogreen, B

    2009-07-06T23:59:59.000Z

    This paper describes new research being performed to improve understanding of seismic waves generated by underground nuclear explosions (UNE) by using full waveform simulation, high-performance computing and three-dimensional (3D) earth models. The goal of this effort is to develop an end-to-end modeling capability to cover the range of wave propagation required for nuclear explosion monitoring (NEM) from the buried nuclear device to the seismic sensor. The goal of this work is to improve understanding of the physical basis and prediction capabilities of seismic observables for NEM including source and path-propagation effects. We are pursuing research along three main thrusts. Firstly, we are modeling the non-linear hydrodynamic response of geologic materials to underground explosions in order to better understand how source emplacement conditions impact the seismic waves that emerge from the source region and are ultimately observed hundreds or thousands of kilometers away. Empirical evidence shows that the amplitudes and frequency content of seismic waves at all distances are strongly impacted by the physical properties of the source region (e.g. density, strength, porosity). To model the near-source shock-wave motions of an UNE, we use GEODYN, an Eulerian Godunov (finite volume) code incorporating thermodynamically consistent non-linear constitutive relations, including cavity formation, yielding, porous compaction, tensile failure, bulking and damage. In order to propagate motions to seismic distances we are developing a one-way coupling method to pass motions to WPP (a Cartesian anelastic finite difference code). Preliminary investigations of UNE's in canonical materials (granite, tuff and alluvium) confirm that emplacement conditions have a strong effect on seismic amplitudes and the generation of shear waves. Specifically, we find that motions from an explosion in high-strength, low-porosity granite have high compressional wave amplitudes and weak shear waves, while an explosion in low strength, high-porosity alluvium results in much weaker compressional waves and low-frequency compressional and shear waves of nearly equal amplitude. Further work will attempt to model available near-field seismic data from explosions conducted at NTS, where we have accurate characterization of the sub-surface from the wealth of geological and geophysical data from the former nuclear test program. Secondly, we are modeling seismic wave propagation with free-surface topography in WPP. We have model the October 9, 2006 and May 25, 2009 North Korean nuclear tests to investigate the impact of rugged topography on seismic waves. Preliminary results indicate that the topographic relief causes complexity in the direct P-waves that leads to azimuthally dependent behavior and the topographic gradient to the northeast, east and southeast of the presumed test locations generate stronger shear-waves, although each test gives a different pattern. Thirdly, we are modeling intermediate period motions (10-50 seconds) from earthquakes and explosions at regional distances. For these simulations we run SPECFEM3D{_}GLOBE (a spherical geometry spectral element code). We modeled broadband waveforms from well-characterized and well-observed events in the Middle East and central Asia, as well as the North Korean nuclear tests. For the recent North Korean test we found that the one-dimensional iasp91 model predicts the observed waveforms quite well in the band 20-50 seconds, while waveform fits for available 3D earth models are generally poor, with some exceptions. Interestingly 3D models can predict energy on the transverse component for an isotropic source presumably due to surface wave mode conversion and/or multipathing.

  2. The Community Environmental Monitoring Program: Reducing Public Perception of Risk through Stakeholder Involvement

    SciTech Connect (OSTI)

    William T. Hartwell

    2007-05-21T23:59:59.000Z

    The Community Environmental Monitoring Program (CEMP) has promoted stakeholder involvement, awareness, and understanding of radiological surveillance in communities surrounding the Nevada Test Site (NTS) since 1981. It involves stakeholders in the operation, data collection, and dissemination of information obtained from a network of 29 stations across a wide area of Nevada, Utah and California. It is sponsored by the U.S. Department of Energy, National Nuclear Security Administration’s Nevada Site Office (NNSA/NSO) and administered by the Desert Research Institute (DRI) of the Nevada System of Higher Education. Integration of a near real-time communications system, a public web site, training workshops for involved stakeholders, and educational programs all help to alleviate public perception of risk of health effects from past activities conducted at the NTS.

  3. Proposed Tenaska Washington II Generation Project : Final Environmental Impact Statement. Volume 2: Public Involvement.

    SciTech Connect (OSTI)

    United States. Bonneville Power Administration.

    1994-01-01T23:59:59.000Z

    In regard to the proposed Tenaska Washington II Generation Project, the goal of the Bonneville Power Administration`s (BPA) Environmental Impact Statement (EIS) public involvement process is to determine the issues to be examined and pertinent analyses to be conducted and to solicit comments on the content and quality of information presented in the Draft Environmental Impact Statement (DEIS). Comments and questions are solicited from the public and government agencies during the scoping process and during the comment period and public hearing on the DEIS, to find out what is of most concern to them. The end product of the public involvement process is the Comment Report which follows in part of this volume on Public Involvement.

  4. Staying Competitive in the 90's: How to Make Public Involvement Work for Your Energy Project

    E-Print Network [OSTI]

    Loveless, K. W.

    STAYING COMPETITIVE IN THE 90'S: HOW TO MAKE PUBLIC INVOL VEMENT WORK FOR YOUR ENERGY PROJECT Kat11Y Wood LOVl;!cSS, Prcsidl;l1t, Loveless EnLerprises, Inc., Salt Lake City, Utah ABSTRACT Gone are the days when energy companies could develop... in Washington, D. c., and Denver. She has been analyzing, planning, conducting public involvement events for more than 2 decades. For a free copy of more public involvement techniques call 801-363-1807 or write: 267 E. North Sandrun Rd.,Salt Lake City, Utah...

  5. Study Finds that Children with Autism and Gastrointestinal Symptoms Have Altered Expression of Genes Involved in Digestion

    E-Print Network [OSTI]

    Salzman, Daniel

    of Genes Involved in Digestion These changes may also affect the mix of bacteria present in the digestive disturbances have altered expression of genes involved in digestion. These variations may contribute to changes

  6. A study to examine community involvement in major U.S.military base closures and realignments from 1988 to 2001

    E-Print Network [OSTI]

    Yahn, Nancy Stiles

    2005-11-01T23:59:59.000Z

    This study examines community involvement in major U.S. military base closures and realignments from 1988 to 2001. There were four waves of base closures during this time. They were in 1988, 1991, 1993, and 1995. Community involvement became...

  7. Amination of Ketenes: Evidence for a Mechanism Involving Enols of Amides as Intermediates

    E-Print Network [OSTI]

    Nguyen, Minh Tho

    effects are modeled by different methods: Onsager SCRF, PCM, and SCI-PCM electrostatic continuum solvation

  8. Nano-Electro-Mechanical (NEM) Relay Devices and Technology for Ultra-Low Energy Digital Integrated Circuits

    E-Print Network [OSTI]

    Nathanael, Rhesa

    2012-01-01T23:59:59.000Z

    II,” Journal of Microelectromechanical Systems, vol. 12, no.Journal of Microelectromechanical Systems, vol. 6, no. 2,Journal of Microelectromechanical Systems, vol. 16, no. 1,

  9. Nano-Electro-Mechanical (NEM) Relay Devices and Technology for Ultra-Low Energy Digital Integrated Circuits

    E-Print Network [OSTI]

    Nathanael, Rhesa

    2012-01-01T23:59:59.000Z

    designing circuits using relays. Test chips were fabricatedwith the test setup cooled with liquid nitrogen show relaystests [15]. Unfortunately, it is not practical to keep testing the relay

  10. Comparison of Bottom-Up and Top-Down Forecasts: Vision Industry Energy Forecasts with ITEMS and NEMS 

    E-Print Network [OSTI]

    Roop, J. M.; Dahowski, R. T

    2000-01-01T23:59:59.000Z

    of the Department of Energy's Office of Industrial Technologies, EIA extracted energy use infonnation from the Annual Energy Outlook (AEO) - 2000 (8) for each of the seven # The Pacific Northwest National Laboratory is operated by Battelle Memorial Institute... Energy Technology Conference, Houston, Texas, pp.115-124. 7. U.S. Department of Energy. 1994. Manufacturing Consumption ofEnergy, J99J. DOEIEIA-0512(91). Washington, D. C. 8. U.S. Department of Energy. 1999. Annual Energy Outlook. 2000...

  11. REL ATRIO DE DESENVOLVIMENTO HUMANO 2007/2008 1 "O progresso humano no automtico nem inevitvel. Somos actualmente con ontados

    E-Print Network [OSTI]

    pobres do mundo, milhões de pessoas são já obrigadas a lidar com os impactos das alterações climáticas. Esses impactos não captam uma atenção de destaque nos meios de comunicação mundiais en- quanto eventos número de situações de seca, de tempestades mais violentas, de cheias, e de stress ambiental está

  12. Developing governmental decision strategies for determining involvement in highly uncertain, large-scale capital investment projects

    E-Print Network [OSTI]

    Golden, Robert J

    1978-01-01T23:59:59.000Z

    to the project. Finally, in order to test the model's applicability in assisting governmental decision-makers to rationally allocate resources, the model has been empirically tested by a Westinghouse proposal (concerning offshore floating nuclear power... . Classification of Models . Models as a Frame of Reference The Contextual Matrix Development of the Matrix Model Methodology Exmployed to Utilize ~ ~ ~ ~ the 27 29 30 32 33 Matrix Framework . IV. WESTINGHOUSE'S OFFSHORE FLOATING NUCLEAR POWER PLANT...

  13. RASRAFMEK-dependent oxidative cell death involving voltage-dependent anion channels

    E-Print Network [OSTI]

    Stockwell, Brent R.

    LETTERS RAS­RAF­MEK-dependent oxidative cell death involving voltage-dependent anion channels J. Fridman1 , Adam J. Wolpaw1 , Inese Smukste1 , John M. Peltier3 , J. Jay Boniface3 , Richard Smith that discriminate between the genetic makeup of normal cells and tumour cells are valuable for treating and under

  14. Quantitative traits loci (QTL) involved in body colour, wing morphometry, cuticular hydrocarbons

    E-Print Network [OSTI]

    Quantitative traits loci (QTL) involved in body colour, wing morphometry, cuticular hydrocarbons for wing morphometry, 12 for cuticular hydrocarbons and five for venom components. We detected 50 QTL / cuticular hydrocarbons / venom 1. INTRODUCTION The first genetic map built from RAPD markers (Hunt and Page

  15. A continuous fluorescence displacement assay for BioA: An enzyme involved in biotin biosynthesis

    E-Print Network [OSTI]

    Thomas, David D.

    ) carboxylases involved in fatty acid metabolism and pyruvate carboxylase in gluco- neogenesis [5]. Biotin] and alanine to afford (8S)-8-amino-7-oxononanoic acid 2, whose more common trivial name is 7-keto-8-aminopelargonic acid (KAPA) (Fig. 1) [9,10]. In the second step, KAPA 2 is transaminated to (7R,8S)-7

  16. CLOUD CHAMBER: A PERFORMANCE INVOLVING REAL TIME TWO-WAY INTERACTION BETWEEN SUBATOMIC RADIOACTIVE

    E-Print Network [OSTI]

    Miranda, Eduardo Reck

    " by the radiation-generated ion patterns in the glass chamber. If John plays in one way the ion particlesCLOUD CHAMBER: A PERFORMANCE INVOLVING REAL TIME TWO-WAY INTERACTION BETWEEN SUBATOMIC RADIOACTIVE, Harwell, Oxford, UK ABSTRACT ,,Cloud Chamber is a live performance created by composer Alexis Kirke

  17. Response to Xanthomonas campestris pv. vesicatoria in Tomato Involves Regulation of Ethylene Receptor

    E-Print Network [OSTI]

    Klee, Harry J.

    Response to Xanthomonas campestris pv. vesicatoria in Tomato Involves Regulation of Ethylene ethylene's role in plant response to virulent and avirulent strains of Xanthomonas campestris pv overexpressing a wild-type NR cDNA were infected with virulent X. campestris pv. vesicatoria. Like the Nr mutant

  18. Guidance for Preparing Research Proposals Involving Diagnostic Use of Ionizing Radiation in Human Use Research

    E-Print Network [OSTI]

    Kay, Mark A.

    Guidance for Preparing Research Proposals Involving Diagnostic Use of Ionizing Radiation in Human Use Research Introduction This guidance has been prepared by the Clinical Radiation Safety Committee of ionizing radiation. CRSCo serves under California Department of Health Services regulations and Nuclear

  19. On the Cover: One route to harvesting the energy of the sun involves learning to mimic

    E-Print Network [OSTI]

    Wu, Zhigang

    #12;On the Cover: One route to harvesting the energy of the sun involves learning to mimic natural the chlorophylls, which play a central role in capturing light and using its energy for photosynthesis in green, and atmospheric carbon dioxide. #12;BASIC RESEARCH NEEDS FOR SOLAR ENERGY UTILIZATION Report on the Basic Energy

  20. Ohio State Colleges/Units Involved College of Arts and Sciences

    E-Print Network [OSTI]

    Nahar, Sultana Nurun

    Affairs Community Partners Involved Indian Universities: Aligarh Muslim University Delhi University Saudi Arabian universities Obama-Singh 21st Century Knowledge Initiative Award Project: STEM Education members. For the project, the OSU partnership with Aligarh Muslim University (AMU) in India received one

  1. Director, MIT Libraries A great benefit of involvement in the planning for MIT's 150th

    E-Print Network [OSTI]

    Reuter, Martin

    Director, MIT Libraries A great benefit of involvement in the planning for MIT's 150th anniversary, and then sustain, MIT's novel and visionary educational philosophy of "Mens et Manus." MIT's future- oriented a university library system that is, like MIT itself, inventive and forward looking. From an early expectation

  2. DNA Identification of Mountain Lions Involved in Livestock Predation and Public Safety Incidents and Investigations

    E-Print Network [OSTI]

    Ernest, Holly

    1 DNA Identification of Mountain Lions Involved in Livestock Predation and Public Safety Incidents concolor, bobcat, forensic, genetics, DNA techniques, noninvasive sampling, fecal DNA, prey swab DNA ABSTRACT Using three case studies, we demonstrated the utility of techniques to analyze DNA from trace

  3. Involvement of the Czech environmental movements in the European game: which impact on their repertory of

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    73 Involvement of the Czech environmental movements in the European game: which impact observe that each country is embedded in its own history. Communism for example, has been experienced. In my own case, these issues have been analysed using Czech environmental actors. #12;Social Movement

  4. PROJECT GOALS This project involved the development of the first Carbon

    E-Print Network [OSTI]

    emissions, which will in turn allow prioritisation of actions to reduce the ANU carbon footprint. TYPEPROJECT GOALS This project involved the development of the first Carbon Emissions Inventory report and master Excel spreadsheet Figure 1: ANU Carbon Emission by Category (t CO2e) DESCRIPTION

  5. MINIMIZERS OF COST-FUNCTIONS INVOLVING NONSMOOTH DATA-FIDELITY TERMS. APPLICATION TO THE

    E-Print Network [OSTI]

    Nikolova, Mila

    MINIMIZERS OF COST-FUNCTIONS INVOLVING NONSMOOTH DATA-FIDELITY TERMS. APPLICATION TO THE PROCESSING cost- function F(x, y) = (x, y) + (x), where is a data-fidelity term, is a smooth regularization term construct a cost-function allowing aberrant data (outliers) to be detected and to be selectively smoothed

  6. PCA-based bootstrap confidence interval tests for gene-disease association involving multiple SNPs

    E-Print Network [OSTI]

    Peng, Qianqian; Zhao, Jinghua; Xue, Fuzhong

    2010-01-26T23:59:59.000Z

    2005, 77:567-581. 23. Kallberg H, Padyukov L, Plenge RM, Ronnelid J, Gregersen PK, Helm-van Mil van der AHM, Toes REM, Huizinga TW, Klareskog L, Alfredsson L, et al: Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking...

  7. Cytosolic High Km 5 -Nucleotidase and 5 (3 )-Deoxyribonucleotidase in Substrate Cycles Involved in Nucleotide Metabolism*

    E-Print Network [OSTI]

    Bianchi, Vera

    in Nucleotide Metabolism* Received for publication, August 21, 2000, and in revised form, November 14, 2000 that the hkm-NT is not involved in the regulation of deoxyribo- nucleotide pools but affects IMP and GTP pools. dNT-1, instead, appears to be the catabolic arm of substrate cycles regulating pyrimidine nucleotide

  8. Statistical Issues in the Study of Air Pollution Involving Airborne Particulate Matter

    E-Print Network [OSTI]

    Washington at Seattle, University of

    of the Workshop was to initiate a statistical research program relevant to setting air quality standardsStatistical Issues in the Study of Air Pollution Involving Airborne Particulate Matter Lawrence H. Cox NRCSET e c h n i c a l R e p o r t S e r i e s NRCSE-TRS No. 041 January 10, 2000 The NRCSEwas

  9. Emergency Action Plan For incidents involving hazardous materials, fires, explosions, or natural gas

    E-Print Network [OSTI]

    Mojzsis, Stephen J.

    -492-6025. For Non-Emergency Fire and Natural Gas Questions call the CU Fire Marshall @ 303-492-4042. AdditionalEmergency Action Plan For incidents involving hazardous materials, fires, explosions, or natural gas leaks, the following actions should be taken: 1) Life Safety First 2) Evacuate Immediate Area 3

  10. Differing Professional Opinions Manual for Technical Issues Involving Environment, Safety, and Health

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2006-11-16T23:59:59.000Z

    This Manual establishes a differing professional opinion (DPO) policy to a Department of Energy (DOE) Differing Professional Opinion (DPO) Process to encourage and facilitate dialogue and resolution on DPOs from employees for technical issues involving environment, safety, and health. Does not cancel other directives. Canceled by DOE O 442.2.

  11. Utility/Industry Partnerships Involving Distributed Generation Technologies in Evolving Electricity Markets

    E-Print Network [OSTI]

    Rastler, D. M.

    Wires Manage Wires defer capital Optimize Energy Services Not Utility Business Not Utility Business New Business Opportunities DISTRIBUTED GENERATION Distributed generation includes small gas turbines, micro-turbines, fuel cells, storage...UTILITYIINDUSTRY PARTNERSHIPS INVOLVING DISTRIBUTED GENERATION TECHNOLOGIES IN EVOLVING ELECTRICITY MARKETS Daniel M. Rastler Manager, Fuel Cells and Distributed Generation Electric Power Research Institute Palo Alto, California ABSTRACT...

  12. Weather encapsulates the state of the atmosphere, primarily involving the component which affects

    E-Print Network [OSTI]

    Allan, Richard P.

    1 #12;2 Weather encapsulates the state of the atmosphere, primarily involving the component which and Telegraph readers tend to use oF #12;5 The human body has an energy balance just like the Earth (solar range in larger on still, clear days, when solar heating is strong at the surface and is not offset

  13. Eight interesting identities involving the exponential function, derivatives, and Stirling numbers of the second kind

    E-Print Network [OSTI]

    Qi, Feng

    2012-01-01T23:59:59.000Z

    In the paper, the author establishes some identities which show that the functions $\\frac1{(1-e^{\\pm t})^k}$ and the derivatives $\\bigl(\\frac1{e^{\\pm t}-1}\\bigr)^{(i)}$ can be expressed each other by linear combinations with coefficients involving the combinatorial numbers and the Stirling numbers of the second kind, where $t\

  14. Thermal Sciences The thermal sciences area involves the study of energy conversion and transmission, power

    E-Print Network [OSTI]

    New Hampshire, University of

    Thermal Sciences The thermal sciences area involves the study of energy conversion and transmission, power generation, the flow of liquids and gases, and the transfer of thermal energy (heat) by means in virtually all energy conversion devices and systems. One may think of the jet engine as a mechanical device

  15. Second-order integrals of motion for spin involving systems in $E_2$

    E-Print Network [OSTI]

    Ismet Yurdusen

    2014-07-16T23:59:59.000Z

    In two-dimensional Euclidean plane, existence of second-order integrals of motion is investigated for integrable Hamiltonian systems involving spin (\\emph{e.g.,} those systems describing interaction between two particles with spin 0 and spin 1/2) and it has been shown that no nontrivial second-order integrals of motion exist for such systems.

  16. Predicting Pelvic Lymph Node Involvement in Current-Era Prostate Cancer

    SciTech Connect (OSTI)

    Rahman, Sophia, E-mail: sophs1578@yahoo.com [Kaiser Permanente Medical Center, Department of Radiation Oncology, Los Angeles, CA (United States); Cosmatos, Harry [Kaiser Permanente Medical Center, Department of Radiation Oncology, Los Angeles, CA (United States); Dave, Giatri [Kaiser Permanente Medical Center, Department of Radiation Oncology, Fresno, CA (United States); Williams, Stephen [Kaiser Permanente Medical Center, Department of Urology, Los Angeles, CA (United States); Tome, Michael [Kaiser Permanente Medical Center, Department of Radiation Oncology, Los Angeles, CA (United States)

    2012-02-01T23:59:59.000Z

    Purpose: The Roach formula [2/3 Multiplication-Sign prostate-specific antigen + (Gleason score - 6) Multiplication-Sign 10], derived in 1993 during the early prostate specific antigen (PSA) screening era, has been used to predict the risk of pelvic lymph node involvement in patients with prostate cancer. In the current era of widespread PSA screening with a shift to earlier disease stages, there is evidence to suggest that the Roach score overestimates risk of nodal metastasis. This study retrospectively reviews the validity of this formula as a prediction tool. Methods and Materials: We conducted a retrospective institutional review including men with clinical T1c-T3 prostate cancer, with baseline PSA levels and biopsy-obtained Gleason scores who underwent radical prostatectomy with pelvic node dissection from 2001 through 2009 (N = 1,022). The predicted risk of nodal involvement was calculated for each patient using the Roach formula and then compared with actual rates following surgery. Results: The study included 1,022 patients; 99.6% had clinical T1c/T2 disease, with a mean of 10.3 lymph nodes surgically evaluated. Overall, 42 patients (4.1%) had nodal metastasis. For every range of scores, the Roach formula overestimates the risk of nodal involvement. Observed nodal positivity was 1%, 6.3%, 10%, 15.2%, and 16.7% for Roach scores {<=}10%, >10%-20%, >20%-30%, >30%-40%, and >40%, respectively. The Roach score overestimates the risk by approximately 4.5-fold in patients with scores {<=}10%, by 2.5-fold for all scores between 10% and 40%, and by 4-fold for scores >40%. Conclusion: The Roach formula overpredicts the risk of pelvic nodal involvement in current-era prostate cancer patients undergoing regular PSA screening and with mainly T1c/T2 disease. Contemporary patients are much less likely to have nodal involvement for a given PSA and Gleason score.

  17. The potential of plug-in hybrid electric vehicles to reduce petroleum use issues involved in developing reliable estimates.

    SciTech Connect (OSTI)

    Vyas, A. D.; Santini, D. J.; Johnson, L. R.; Energy Systems

    2009-01-01T23:59:59.000Z

    This paper delineates the various issues involved in developing reliable estimates of the petroleum use reduction that would result from the wide-spread introduction of plug-in hybrid electric vehicles (PHEVs). Travel day data from the 2001 National Household Travel Survey (NHTS) were analyzed to identify the share of vehicle miles of travel (VMT) that could be transferred to grid electricity. Various PHEV charge-depleting (CD) ranges were evaluated, and 100% CD mode and potential blended modes were analyzed. The NHTS data were also examined to evaluate the potential for PHEV battery charging multiple times a day. Data from the 2005 American Housing Survey (AHS) were analyzed to evaluate the availability of garages and carports for at-home charging of the PHEV battery. The AHS data were also reviewed by census region and household location within or outside metropolitan statistical areas. To illustrate the lag times involved, the historical new vehicle market share increases for the diesel power train in France (a highly successful case) and the emerging hybrid electric vehicles in the United States were examined. A new vehicle technology substitution model is applied to illustrate a historically plausible successful new PHEV market share expansion. The trends in U.S. light-duty vehicle sales and light-duty vehicle stock were evaluated to estimate the time required for hypothetical successful new PHEVs to achieve the ultimately attainable share of the existing vehicle stock. Only when such steps have been accomplished will the full oil savings potential for the nation be achieved.

  18. Defining and Model Checking Abstractions of Complex Railway Models using CSP||B

    E-Print Network [OSTI]

    Doran, Simon J.

    Defining and Model Checking Abstractions of Complex Railway Models using CSP||B Faron Moller1. In [11, 10] we propose a new modelling approach for railway interlockings. We use CSP||B [13], which involves events such as train movements and, in the interlocking, state based reasoning. In this sense, CSP

  19. MODELLING GAS HYDRATE EQUILIBRIA USING THE ELECTROLYTE NON-RANDOM TWO-LIQUID (ENRTL) MODEL

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    MODELLING GAS HYDRATE EQUILIBRIA USING THE ELECTROLYTE NON-RANDOM TWO-LIQUID (ENRTL) MODEL Matthias" developed in our group and allowing for performing equilibrium calculations involving gas hydrate phases of state approach for the gas phase, the van-der-Waals and Platteeuw model for the clathrate hydrate phase

  20. Alternatives to traditional model comparison strategies for covariance structure models

    E-Print Network [OSTI]

    Preacher, K. J.; Cai, Li; MacCallum, R. C.

    2007-01-01T23:59:59.000Z

    involving an extension of recently introduced methods to nested model scenarios. Following our discussion of power, we further explore the potential value of adopting a model selection approach that avoids hypoth- a105 ?Chapter3?Preacher? ? 2007/2/12 ? 15... is literally true, there is an obvious logical problem in testing the null hypothesis that a model fits data perfectly in the population. Yet, this is precisely the hypothesis tested by the popular LR test of model a105 ?Chapter3?Preacher? ? 2007/2/12 ? 15...

  1. How to explore new business models for technological innovations

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    How to explore new business models for technological innovations Valérie Chanal Grenoble University also involved business model innovation. Exploration of new business models is however particularly to target. This article proposes a scenario-based method for exploring business models for technological

  2. Public involvement in integrated resource planning: A study of demand-side management collaboratives

    SciTech Connect (OSTI)

    Raab, J. (Raab (J.), Boston, MA (United States)); Schweitzer, M. (Oak Ridge National Lab., TN (United States))

    1992-02-01T23:59:59.000Z

    Many utilities and nonutility parties (NUPs) across the country have tried a new approach to reaching agreement on Demand-Side Management (DSM) program design and policy issues. Through this, which is called the DSM collaborative process, parties who have often been adversaries in the past attempt to reach consensus rather than using traditional litigation to resolve differences. We examined nine cases of DSM collaboration involving 24 utilities and approximately 50 NUPs in 10 states. This is the first comprehensive, in-depth review and assessment of collaboratives and it allows conclusions to be drawn about the collaborative process and the factors that contribute to successful efforts of this type. Collaboratives are described in terms of four major contextual and organizational characteristics: regulatory and legal history, parties involved and parties excluded, collaborative scope, and the collaborative process itself.

  3. Spatial arrangement of trail markers and visitor involvement on a self-guided interpretive trail 

    E-Print Network [OSTI]

    Marcy, Julie Benedict

    1982-01-01T23:59:59.000Z

    be presented by asking "what constitutes an effective SGT in terms of visitor involvement with t'ne trail, leaflet suggestions, and the spacing of stakes or markers on the trail?" An effecrive program or technique is one which achieves its desired... concluded with open-ended questions on suggested improvements for the trail and leaflet. Sontag (27) states rhat there are three main ccmponents of t. rail evaluation: personal objeccive evaluation, observing visitor reaction, and questionnaires...

  4. TEC protein tyrosine kinase is involved in the Erk signaling pathway induced by HGF

    SciTech Connect (OSTI)

    Li, Feifei; Jiang, Yinan [Department of Pathophysiology, Anhui Medical University, Hefei 230032 (China)] [Department of Pathophysiology, Anhui Medical University, Hefei 230032 (China); Zheng, Qiping [Department of Anatomy and Cell Biology, Rush University Medical Center, Chicago, IL 60612 (United States)] [Department of Anatomy and Cell Biology, Rush University Medical Center, Chicago, IL 60612 (United States); Yang, Xiaoming [Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850 (China)] [Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850 (China); Wang, Siying, E-mail: sywang@ahmu.edu.cn [Department of Pathophysiology, Anhui Medical University, Hefei 230032 (China)] [Department of Pathophysiology, Anhui Medical University, Hefei 230032 (China)

    2011-01-07T23:59:59.000Z

    Research highlights: {yields} TEC is rapidly tyrosine-phosphorylated and activated by HGF-stimulation in vivo or after partial hepatectomy in mice. {yields} TEC enhances the activity of Elk and serum response element (SRE) in HGF signaling pathway in hepatocyte. {yields} TEC promotes hepatocyte proliferation through the Erk-MAPK pathway. -- Abstract: Background/aims: TEC, a member of the TEC family of non-receptor type protein tyrosine kinases, has recently been suggested to play a role in hepatocyte proliferation and liver regeneration. This study aims to investigate the putative mechanisms of TEC kinase regulation of hepatocyte differentiation, i.e. to explore which signaling pathway TEC is involved in, and how TEC is activated in hepatocyte after hepatectomy and hepatocyte growth factor (HGF) stimulation. Methods: We performed immunoprecipitation (IP) and immunoblotting (IB) to examine TEC tyrosine phosphorylation after partial hepatectomy in mice and HGF stimulation in WB F-344 hepatic cells. The TEC kinase activity was determined by in vitro kinase assay. Reporter gene assay, antisense oligonucleotide and TEC dominant negative mutant (TEC{sup KM}) were used to examine the possible signaling pathways in which TEC is involved. The cell proliferation rate was evaluated by {sup 3}H-TdR incorporation. Results: TEC phosphorylation and kinase activity were increased in 1 h after hepatectomy or HGF treatment. TEC enhanced the activity of Elk and serum response element (SRE). Inhibition of MEK1 suppressed TEC phosphorylation. Blocking TEC activity dramatically decreased the activation of Erk. Reduced TEC kinase activity also suppressed the proliferation of WB F-344 cells. These results suggest TEC is involved in the Ras-MAPK pathway and acts between MEK1 and Erk. Conclusions: TEC promotes hepatocyte proliferation and regeneration and is involved in HGF-induced Erk signaling pathway.

  5. Temperature of aircraft cargo flame exposure during accidents involving fuel spills

    SciTech Connect (OSTI)

    Mansfield, J.A.

    1993-01-01T23:59:59.000Z

    This report describes an evaluation of flame exposure temperatures of weapons contained in alert (parked) bombers due to accidents that involve aircraft fuel fires. The evaluation includes two types of accident, collisions into an alert aircraft by an aircraft that is on landing or take-off, and engine start accidents. Both the B-1B and B-52 alert aircraft are included in the evaluation.

  6. Involvement of HIF-2?-mediated inflammation in arsenite-induced transformation of human bronchial epithelial cells

    SciTech Connect (OSTI)

    Xu, Yuan; Zhao, Yue; Xu, Wenchao; Luo, Fei; Wang, Bairu; Li, Yuan; Pang, Ying; Liu, Qizhan, E-mail: drqzliu@hotmail.com

    2013-10-15T23:59:59.000Z

    Arsenic is a well established human carcinogen that causes diseases of the lung. Some studies have suggested a link between inflammation and lung cancer; however, it is unknown if arsenite-induced inflammation causally contributes to arsenite-caused malignant transformation of cells. In this study, we investigated the molecular mechanisms underlying inflammation during neoplastic transformation induced in human bronchial epithelial (HBE) cells by chronic exposure to arsenite. The results showed that, on acute or chronic exposure to arsenite, HBE cells over-expressed the pro-inflammatory cytokines, interleukin-6 (IL-6), interleukin-8 (IL-8), and interleukin-1? (IL-1?). The data also indicated that HIF-2? was involved in arsenite-induced inflammation. Moreover, IL-6 and IL-8 were essential for the malignant progression of arsenite-transformed HBE cells. Thus, these experiments show that HIF-2? mediates arsenite-induced inflammation and that such inflammation is involved in arsenite-induced malignant transformation of HBE cells. The results provide a link between the inflammatory response and the acquisition of a malignant transformed phenotype by cells chronically exposed to arsenite and thus establish a previously unknown mechanism for arsenite-induced carcinogenesis. - Highlights: • Arsenite induces inflammation. • Arsenite-induced the increases of IL-6 and IL-8 via HIF-2?. • Inflammation is involved in arsenite-induced carcinogenesis.

  7. A review of two recent occurrences at the Advanced Test Reactor involving subcontractor activities

    SciTech Connect (OSTI)

    Dahlke, H.J.; Jensen, N.C.; Vail, J.A.

    1997-11-01T23:59:59.000Z

    This report documents the results of a brief, unofficial investigation into two incidents at the Idaho National Engineering and Environmental Laboratory (INEEL) Advanced Test Reactor (ATR) facility, reported on October 25 and 31, 1997. The first event was an unanticipated breach of confinement. The second involved reactor operation with an inoperable seismic scram subsystem, violating the reactor`s Technical Specifications. These two incidents have been found to be unrelated. A third event that occurred on December 16, 1996, is also discussed because of its similarities to the first event listed above. Both of these incidents were unanticipated breaches of confinement, and both involved the work of construction subcontractor personnel. The cause for the subcontractor related occurrences is a work control process that fails to effectively interface with LMITCO management. ATR Construction Project managers work sufficient close with construction subcontractor personnel to understand planned day-to-day activities. They also have sufficient training and understanding of reactor operations to ensure adherence to applicable administrative requirements. However, they may not be sufficiently involved in the work authorization and control process to bridge an apparent communications gap between subcontractor employees and Facility Operations/functional support personnel for work inside the reactor facility. The cause for the inoperable seismic scram switch (resulting from a disconnected lead) is still under investigation. It does not appear to be subcontractor related.

  8. NEAMS FPL M2 Milestone Report: Development of a UO? Grain Size Model using Multicale Modeling and Simulation

    SciTech Connect (OSTI)

    Michael R Tonks; Yongfeng Zhang; Xianming Bai

    2014-06-01T23:59:59.000Z

    This report summarizes development work funded by the Nuclear Energy Advanced Modeling Simulation program's Fuels Product Line (FPL) to develop a mechanistic model for the average grain size in UO? fuel. The model is developed using a multiscale modeling and simulation approach involving atomistic simulations, as well as mesoscale simulations using INL's MARMOT code.

  9. Thermodynamic and kinetic modeling of transcriptional pausing

    E-Print Network [OSTI]

    Chen, Kuang-Yu

    in the cotranscriptional RNA secondary structure upstream of the RNA exit channel. The calculations involve no adjustable of recovery of backtracked paused complexes. A crucial ingredient of our model is the incorporation of kinetic secondary structure, an aspect not included explicitly in previous attempts at modeling the transcrip- tion

  10. Lessons 6 Graphs of Functional Models

    E-Print Network [OSTI]

    2013-08-30T23:59:59.000Z

    Aug 30, 2013 ... One of the problems (#1) illustrates the principle of supply and demand, ... All of the problems involve building up a function model (see Lesson 5) ... Granite Management rents out several apartment complexes in the .... Side. 0.001 per cm2. Bottom. 0.005 per cm2. Lessons 6 Graphs of Functional Models.

  11. Queuing models System dynamics models

    E-Print Network [OSTI]

    Glushko, Robert J.

    models Value chain models Business Model / Organizational Perspective Process Perspective Information#12;#12;#12;#12;Queuing models System dynamics models #12;#12;#12;#12;Blueprint or touchpoint

  12. The Function and Genetic Interactions of Zebrafish atoh1 and sox2: Genes Involved in Hair Cell Development and Regeneration

    E-Print Network [OSTI]

    Millimaki, Bonny Butler

    2010-10-12T23:59:59.000Z

    THE FUNCTION AND GENETIC INTERACTIONS OF ZEBRAFISH atoh1 AND sox2: GENES INVOLVED IN HAIR CEL DEVELOPMENT AND REGENERATION A Disertation by BONY BUTLER MILIMAKI Submited to the Ofice of Graduate Studies of Texas A... Involved in Hair Cel Development and Regeneration. Copyright 2010 Bonny Butler Milimaki THE FUNCTION AND GENETIC INTERACTIONS OF ZEBRAFISH atoh1 AND sox2: GENES INVOLVED IN HAIR CEL DEVELOPMENT AND REGENERATION A Disertation by BONY...

  13. THE RELATIONSHIP BETWEEN HIGH INVOLVEMENT WORK SYSTEMS, SUPERVISORY SUPPORT, AND ORGANIZATIONAL EFFECTIVENESS: THE ROLE OF EMPLOYEE EXPERIENCES AT WORK

    E-Print Network [OSTI]

    Wadhwa, Preeti

    2012-08-31T23:59:59.000Z

    This study adopts a multilevel, multiple stakeholder perspective to examine the impact of high involvement work systems (HIWS) and supervisory support on organizational effectiveness. Organizational effectiveness is measured ...

  14. Identification and Characterization of Soluble Factors Involved in Delayed Effects of Low Dose Radiation. Final report

    SciTech Connect (OSTI)

    Baulch, Janet

    2013-09-11T23:59:59.000Z

    This is a 'glue grant' that was part of a DOE Low Dose project entitled 'Identification and Characterization of Soluble Factors Involved in Delayed Effects of Low Dose Radiation'. This collaborative program has involved Drs. David L. Springer from Pacific Northwest National Laboratory (PNNL), John H. Miller from Washington State University, Tri-cities (WSU) and William F. Morgan then from the University of Maryland, Baltimore (UMB). In July 2008, Dr. Morgan moved to PNNL and Dr. Janet E. Baulch became PI for this project at University of Maryland. In November of 2008, a one year extension with no new funds was requested to complete the proteomic analyses. The project stemmed from studies in the Morgan laboratory demonstrating that genomically unstable cells secret a soluble factor or factors into the culture medium, that cause cytogenetic aberrations and apoptosis in normal parental GM10115 cells. The purpose of this project was to identify the death inducing effect (DIE) factor or factors, estimate their relative abundance, identify the cell signaling pathways involved and finally recapitulate DIE in normal cells by exogenous manipulation of putative DIE factors in culture medium. As reported in detail in the previous progress report, analysis of culture medium from the parental cell line, and stable and unstable clones demonstrated inconsistent proteomic profiles as relate to candidate DIE factors. While the proposed proteomic analyses did not provide information that would allow DIE factors to be identified, the analyses provided another important set of observations. Proteomic analysis suggested that proteins associated with the cellular response to oxidative stress and mitochondrial function were elevated in the medium from unstable clones in a manner consistent with mitochondrial dysfunction. These findings correlate with previous studies of these clones that demonstrated functional differences between the mitochondria of stable and unstable clones. These mitochondrial abnormalities in the unstable clones contributes to oxidative stress.

  15. Endoplasmic reticulum stress is involved in arsenite-induced oxidative injury in rat brain

    SciTech Connect (OSTI)

    Lin, Anya M.Y. [Department of Physiology, National Yang-Ming University, Taipei, Taiwan (China); Department of Medical Research and Education, Taipei Veterans General Hospital, Taipei, Taiwan (China); Chao, P.L.; Fang, S.F.; Chi, C.W. [Department of Medical Research and Education, Taipei Veterans General Hospital, Taipei, Taiwan (China); Yang, C.H. [Department of Oncology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan (China)], E-mail: chihyang@ntu.edu.tw

    2007-10-15T23:59:59.000Z

    The mechanism underlying sodium arsenite (arsenite)-induced neurotoxicity was investigated in rat brain. Arsenite was locally infused in the substantia nigra (SN) of anesthetized rat. Seven days after infusion, lipid peroxidation in the infused SN was elevated and dopamine level in the ipsilateral striatum was reduced in a concentration-dependent manner (0.3-5 nmol). Furthermore, local infusion of arsenite (5 nmol) decreased GSH content and increased expression of heat shock protein 70 and heme oxygenase-1 in the infused SN. Aggregation of {alpha}-synuclein, a putative pathological protein involved in several CNS neurodegenerative diseases, was elevated in the arsenite-infused SN. From the breakdown pattern of {alpha}-spectrin, both necrosis and apoptosis were involved in the arsenite-induced neurotoxicity. Pyknotic nuclei, cellular shrinkage and cytoplasmic disintegration, indicating necrosis, and TUNEL-positive cells and DNA ladder, indicating apoptosis was observed in the arsenite-infused SN. Arsenite-induced apoptosis was mediated via two different organelle pathways, mitochondria and endoplasmic reticulum (ER). For mitochondrial activation, cytosolic cytochrome c and caspase-3 levels were elevated in the arsenite-infused SN. In ER pathway, arsenite increased activating transcription factor-4, X-box binding protein 1, C/EBP homologues protein (CHOP) and cytosolic immunoglobulin binding protein levels. Moreover, arsenite reduced procaspase 12 levels, an ER-specific enzyme in the infused SN. Taken together, our study suggests that arsenite is capable of inducing oxidative injury in CNS. In addition to mitochondria, ER stress was involved in the arsenite-induced apoptosis. Arsenite-induced neurotoxicity clinically implies a pathophysiological role of arsenite in CNS neurodegeneration.

  16. Fatal accidents involving roof falls in coal mining, 1996--1998

    SciTech Connect (OSTI)

    Not Available

    1999-01-01T23:59:59.000Z

    This publication presents information on fatalities involving roof and rib falls that occurred in coal mining operations from January 1996 through December 1998. It includes statistics for the fatalities, as well as abstracts, best practices and illustrations. Conclusion statements have been substituted for best practices where no Title 30 Code of Regulations violations were cited during the accident investigation. From January 1996 through December 1998, 36 miners died at coal operations from accidents classified as roof falls. The information in the report is based on statistics taken from the 1996 through 1998 MSHA Fatal Illustration Programs: Roof Fall Fatalities by District.

  17. Fatal accidents involving roof falls in coal mining, 1996--1998

    SciTech Connect (OSTI)

    NONE

    1999-11-01T23:59:59.000Z

    This publication presents information on fatalities involving roof and rib falls that occurred in coal mining operations from January 1996 through December 1998. It includes statistics for the fatalities, as well as abstracts, best practices and illustrations. Conclusion statements have been substituted for best practices where no Title 30 Code of Regulations violations were cited during the accident investigation. From January 1996 through December 1998, 36 miners died at coal operations from accidents classified as roof falls. The information in the report is based on statistics taken from the 1996 through 1998 MSHA Fatal Illustration Programs: Roof Fall Fatalities by District.

  18. The Conducting of a Mining Negotiation Showing the Scheme of Engineering Involved

    E-Print Network [OSTI]

    Hansen, George T.

    1911-01-01T23:59:59.000Z

    and capable of lifting the heaviest piece of any one of these machines. CEAIIT BLOCKS:- One fl) 8 ton triplex chain block, complete, equip- ped with sufficient chain for a 14* lift. One (1) 3 ton triplex chain block, equipped with sufficient chain for a 22... E S I S , "The conducting of a Mining negotiation Show- ng the Scheme of Engineering Involved." Taken from Actual Practice 13 7 SEQRGE T. HAISB1 MIIIIS SALES EET5IHEBR ALLIS GHALMBBS OOMPASY ST. LOUIS, MISSOURI Presented to the College...

  19. A new approach for modeling the peak utility impacts from a proposed CUAC standard

    E-Print Network [OSTI]

    LaCommare, Kristina Hamachi; Gumerman, Etan; Marnay, Chris; Chan, Peter; Coughlin, Katie

    2004-01-01T23:59:59.000Z

    47 6.5 The 11 Blocks that Represent the LDC in28 Figure 17. The LDC from 6x TSL 4 for ECAR Region in YearCUAC DOE EIA EMM GW kW LCC LDC LDSM MEF NEMS NERC NES PNNL

  20. Involvement of ERK in NMDA receptor-independent cortical neurotoxicity of hydrogen sulfide

    SciTech Connect (OSTI)

    Kurokawa, Yuko; Sekiguchi, Fumiko; Kubo, Satoko; Yamasaki, Yoshiko; Matsuda, Sachi; Okamoto, Yukari; Sekimoto, Teruki; Fukatsu, Anna; Nishikawa, Hiroyuki [Division of Pharmacology and Pathophysiology, Kinki University School of Pharmacy, 3-4-1 Kowakae, Higashi-Osaka 577-8502 (Japan)] [Division of Pharmacology and Pathophysiology, Kinki University School of Pharmacy, 3-4-1 Kowakae, Higashi-Osaka 577-8502 (Japan); Kume, Toshiaki [Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-shimoadachi-cho, Sakyo-ku, Kyoto 606-8501 (Japan)] [Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-shimoadachi-cho, Sakyo-ku, Kyoto 606-8501 (Japan); Fukushima, Nobuyuki [Division of Molecular Neurobiology, Department of Life Sciences, Kinki University School of Science and Engineering, 3-4-1 Kowakae, Higashi-Osaka 577-8502 (Japan)] [Division of Molecular Neurobiology, Department of Life Sciences, Kinki University School of Science and Engineering, 3-4-1 Kowakae, Higashi-Osaka 577-8502 (Japan); Akaike, Akinori [Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-shimoadachi-cho, Sakyo-ku, Kyoto 606-8501 (Japan)] [Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-shimoadachi-cho, Sakyo-ku, Kyoto 606-8501 (Japan); Kawabata, Atsufumi, E-mail: kawabata@phar.kindai.ac.jp [Division of Pharmacology and Pathophysiology, Kinki University School of Pharmacy, 3-4-1 Kowakae, Higashi-Osaka 577-8502 (Japan)] [Division of Pharmacology and Pathophysiology, Kinki University School of Pharmacy, 3-4-1 Kowakae, Higashi-Osaka 577-8502 (Japan)

    2011-11-04T23:59:59.000Z

    Highlights: Black-Right-Pointing-Pointer Hydrogen sulfide causes NMDA receptor-independent neurotoxicity in mouse fetal cortical neurons. Black-Right-Pointing-Pointer Activation of ERK mediates the toxicity of hydrogen sulfide. Black-Right-Pointing-Pointer Apoptotic mechanisms are involved in the hydrogen-induced cell death. -- Abstract: Hydrogen sulfide (H{sub 2}S), a gasotransmitter, exerts both neurotoxicity and neuroprotection, and targets multiple molecules including NMDA receptors, T-type calcium channels and NO synthase (NOS) that might affect neuronal viability. Here, we determined and characterized effects of NaHS, an H{sub 2}S donor, on cell viability in the primary cultures of mouse fetal cortical neurons. NaHS caused neuronal death, as assessed by LDH release and trypan blue staining, but did not significantly reduce the glutamate toxicity. The neurotoxicity of NaHS was resistant to inhibitors of NMDA receptors, T-type calcium channels and NOS, and was blocked by inhibitors of MEK, but not JNK, p38 MAP kinase, PKC and Src. NaHS caused prompt phosphorylation of ERK and upregulation of Bad, followed by translocation of Bax to mitochondria and release of mitochondrial cytochrome c, leading to the nuclear condensation/fragmentation. These effects of NaHS were suppressed by the MEK inhibitor. Our data suggest that the NMDA receptor-independent neurotoxicity of H{sub 2}S involves activation of the MEK/ERK pathway and some apoptotic mechanisms.

  1. Innocuous oil as an additive for reductive reactions involving zero valence iron

    SciTech Connect (OSTI)

    Cary, J.W.; Cantrell, K.J.

    1994-11-01T23:59:59.000Z

    Reductive reactions involving zero valence iron appear to hold promise for in situ remediation of sites containing chlorinated hydrocarbon solvents and certain reducible metals and radionuclides. Treatment involves the injection of metallic iron and the creation of low levels of dissolved oxygen in the aqueous phase through oxidation of the metallic iron. The use of a biodegradable immiscible and innocuous organic liquid such as vegetable oil as an additive offers several intriguing possibilities. The oil phase creates a large oil-water interface that is immobile with respect to flow in the aqueous phase. This phase will act as a trap for chlorinated hydrocarbons and could potentially increase the reaction efficiency of reductive dehalogenation of chlorinated hydrocarbons by the metallic iron. When iron particles are suspended in the oil before injection they are preferentially held in the oil phase and tend to accumulate at the oil-water interface. Thus oil injection can serve as a mechanism for creating a stable porous curtain of metallic iron in the vadose to maintain a low oxygen environment which will minimize the consumption of the iron by molecular oxygen.

  2. Pseudobond parameters for QM/MM studies involving nucleosides, nucleotides, and their analogs

    SciTech Connect (OSTI)

    Chaudret, Robin [Duke University, North Carolina] [Duke University, North Carolina; Parks, Jerry M [ORNL] [ORNL; Yang, Weitao [Duke University, North Carolina] [Duke University, North Carolina

    2013-01-01T23:59:59.000Z

    In biological systems involving nucleosides, nucleotides, or their respective analogs, the ribose sugar moiety is the most common reaction site, for example, during DNA replication and repair. How- ever, nucleic bases, which comprise a sizable portion of nucleotide molecules, are usually unreactive during such processes. In quantum mechanical/molecular simulations of nucleic acid reactivity, it may therefore be advantageous to describe specific ribosyl or ribosyl phosphate groups quantum me- chanically and their respective nucleic bases with a molecular mechanics potential function. Here, we have extended the pseudobond approach to enable quantum mechanical/molecular mechanical simulations involving nucleotides, nucleosides, and their analogs in which the interface between the two subsystems is located between the sugar and the base, namely, the C(sp3) N(sp2) bond. The pseudobond parameters were optimized on a training set of 10 molecules representing several nu- cleotide and nucleoside bases and analogs, and they were then tested on a larger test set of 20 diverse molecules. Particular emphasis was placed on providing accurate geometries and electrostatic prop- erties, including electrostatic potential, natural bond orbital (NBO) and atoms in molecules (AIM) charges and AIM first moments. We also tested the optimized parameters on five nucleotide and nu- cleoside analogues of pharmaceutical relevance and a small polypeptide (triglycine). Accuracy was maintained for these systems, which highlights the generality and transferability of the pseudobond approach. 2013 American Institute of Physics. [http://dx.doi.org/10.1063/1.4772182

  3. To examine how the dynamics of recall processes are affected by the control processes involved with search termination, to study

    E-Print Network [OSTI]

    Dougherty, Michael

    involved with search termination, to study the implications of these control processes for the development at understanding the metacognitive control processes involved with the decision to terminate memory search. Specifically, research examines the impact of search termination decisions on the natural retrieval dynamics

  4. NRF2 activation is involved in ozonated human serum upregulation of HO-1 in endothelial cells

    SciTech Connect (OSTI)

    Pecorelli, Alessandra [Department of Molecular and Developmental Medicine, University of Siena (Italy); Child Neuropsychiatry Unit, University Hospital, AOUS, Siena (Italy); Bocci, Velio [Department of Physiology, University of Siena (Italy); Acquaviva, Alessandra [Department of Molecular and Developmental Medicine, University of Siena (Italy); Belmonte, Giuseppe [Department of Biomedical Sciences, University of Siena (Italy); Gardi, Concetta [Department of Molecular and Developmental Medicine, University of Siena (Italy); Virgili, Fabio [INRAN, Rome (Italy); Ciccoli, Lucia [Department of Molecular and Developmental Medicine, University of Siena (Italy); Valacchi, Giuseppe, E-mail: giuseppe.valacchi@unife.it [Department of Life Sciences and Biotechnology, University of Ferrara (Italy); Department of Food and Nutrition, Kyung Hee University, Seoul (Korea, Republic of)

    2013-02-15T23:59:59.000Z

    During the last decade, it has been shown that the activation of NRF2 and the binding to electrophile-responsive element (EpREs), stimulates the expression of a great number of genes responsible for the synthesis of phase I and phase II proteins, including antioxidants enzymes and heme oxygenase-1 (HO-1). This critical cell response occurs in cardiovascular, degenerative and chronic infective diseases aggravated by a chronic oxidative stress. In our previous reports we have shown that ozonated plasma is able to up-regulate HO-1 expression in endothelial cells. In the present work we investigated a candidate mechanism involved in this process. After treatment with increasing doses of ozonated serum (20, 40 and 80 ?g/mL O{sub 3} per mL of serum), a clear dose dependent activation of NRF2 and the subsequent induction of HO-1 and NAD(P)H quinone oxidoreductase 1(NQO1) was observed. This effect was also present when cells were treated with serum and hydrogen peroxide (H{sub 2}O{sub 2}) or serum and 4-hydroxynonenal (4HNE). Moreover, the treatment with ozonated serum was associated with a dose-dependent activation of extracellular-signal-regulated kinases (ERK1/2) and p38 MAP kinases (p38), not directly involved in NRF2 activation. These data, provide a new insight on the mechanism responsible for the induction of HO-1 expression by ozonated serum in the endothelium, and have a practical importance as an expedient approach to the treatment of patients with both effective orthodox drugs and ozonated autohemotherapy, targeted to the restoration of redox homeostasis. - Highlights: ? Endothelial HO1 is upregulated by ozonated plasma ? This activation is induced by NRF2 and it is ERK independent. ? 4HNE and H{sub 2}O{sub 2} are the main molecules involved in this process. ? Ozonated plasma induced a hormetic effect ? Combination of orthodox medicine and ozonated plasma can be a useful treatment.

  5. Machining dynamics and stability analysis in longitudinal turning involving workpiece whirling

    E-Print Network [OSTI]

    Dassanayake, Achala Viomy

    2009-06-02T23:59:59.000Z

    to the machining surface to be three-dimensionally established as functions of spindle speed, instantaneous DOC, rate of material removal and whirling. Excluding workpiece vibrations from the cutting model is found improper. A rich set of nonlinear behaviors...

  6. Forward and reverse genetic approaches to identify genes involved in leg morphogenesis in Drosophila

    E-Print Network [OSTI]

    Wang, Xiaochen

    2010-04-26T23:59:59.000Z

    Development of Drosophila leg imaginal discs provides an ideal model to study hormone-regulated morphogenesis. During the onset of metamorphosis, a pulse of ecdysone triggers the rapid transformation of flat leg imaginal ...

  7. Microstructure and strength modelling of AlCuMg alloys during non-isothermal

    E-Print Network [OSTI]

    -clusters Introduction Non-isothermal processes may involve very rapid temperature changes, such as in welding to test/verify the model predictions in situ and in a companion paper the model is applied to welding

  8. Basic Features of a Cell Electroporation Model: Illustrative Behavior for Two Very Different Pulses

    E-Print Network [OSTI]

    Son, Reuben S.

    Science increasingly involves complex modeling. Here we describe a model for cell electroporation in which membrane properties are dynamically modified by poration. Spatial scales range from cell membrane thickness (5 nm) ...

  9. Mathematical Models and Methods in Applied Sciences Vol. 18, No. 10 (2008) 17411785

    E-Print Network [OSTI]

    Bürger, Raimund

    2008-01-01T23:59:59.000Z

    Scientific Publishing Company A GENERALIZED KINETIC MODEL OF SEDIMENTATION OF POLYDISPERSE SUSPENSIONS-dimensional kinematic model for batch sedimentation of polydisperse suspensions of small equal- density spheres.1. Scope Numerous engineering applications involve the sedimentation of small solid particles dispersed

  10. The optimization of a function involving an integral by linear programming techniques

    E-Print Network [OSTI]

    Goeble, Harold Everett

    1969-01-01T23:59:59.000Z

    D. George [13] developed a particular model* to study the production and investment problems of the competitive firm using calculus of variations and optimal control theory. Applications of this work have been performed by Mange [14], Farnsworth... + $88. 69 = $282. 87. Therefore, due to the nature of the time interval as described by the Thompson-George model, the discount function is essential in considering the purchasing power of the firm's capital and it does not realistically assume...

  11. Taking Man Out of the Loop: Methods to Reduce Human Involvement in Search and Surveillance Applications

    E-Print Network [OSTI]

    Brink, Kevin Michael

    2012-02-14T23:59:59.000Z

    for two varied camera parameters. : : : : : : : : : : : : : : : : : : : : : : : : : : : : 30 18 Complementary form Kalman lter design of vision-aided INS sys- tems. The dashed line represents the slower update rate of camera measurements... to source localization using a high delity environment model to directly provide vehicle updates. The approach is an extension of a standard quadratic model that provides linear updates. The new approach leverages information from the higher-order terms...

  12. Closure models for turbulent reacting flows

    SciTech Connect (OSTI)

    Dutta, A.; Tarbell, J.M. (Pennsylvania State Univ., University Park, PA (USA). Dept. of Chemical Engineering)

    1989-12-01T23:59:59.000Z

    In this paper, a simple procedure based on fast and slow reaction asymptotics has been employed to drive first-order closure models for the nonlinear reaction terms in turbulent mass balances from mechanistic models of turbulent mixing and reaction. The coalescence-redispersion (CRD) model, the interaction by exchange with the mean (IEM) model, the three-environment (3E) model, and the four-environment (4E) model have been used to develop closure equations. The closure models have been tested extensively against experimental data for both single and multiple reactions. The closures based on slow asymptotics for the CRD, 3E and 4E models provide very good predictions of all of the experimental data, while other models available either in the literature or derived here are not adequate. The simple new closure equations developed in this paper may be useful in modeling systems involving turbulent mixing and complex chemical reactions.

  13. Health Information Modeling, Simulation, and Analysis: ABMS of HIE Network

    E-Print Network [OSTI]

    Kemner, Ken

    Health Information Exchange Modeling, Simulation, and Analysis: ABMS of HIE Network Opportunity.S. healthcare system would provide a secure, nationwide, interoperable health information infrastructure that connects providers, consumers, and others involved in supporting health and healthcare. Effectively

  14. Effectiveness-Equity Models for Facility Location Problems on Tree ...

    E-Print Network [OSTI]

    2013-01-19T23:59:59.000Z

    pecially in situations that involve public facilities or resources. ... Department of Decision Sciences, School of Business, The George Washington University, Washington, ... First, the proposed models allow one to identify efficient (or Pareto opti-.

  15. Phenomenological models in biological physics : cell growth and pluripotency maintenance

    E-Print Network [OSTI]

    Youk, Hyun

    2010-01-01T23:59:59.000Z

    A persistent challenge in quantitatively modeling a biological system is that the system often involves many components and just as dizzying number of interactions among those components. To further complicate matters, the ...

  16. Engineering change modelling using a function-behaviour-structure scheme

    E-Print Network [OSTI]

    Hamraz, Bahram

    2013-11-12T23:59:59.000Z

    an FBS Linkage model is demonstrated. The method’s potential benefits are discussed. Finally, the application of the method to two industrial case studies involving a diesel engine and a scanning electron microscope is presented. The method evaluation...

  17. Involvement of calcium-sensing receptor in ischemia/reperfusion-induced apoptosis in rat cardiomyocytes

    SciTech Connect (OSTI)

    Zhang Weihua [Department of Pathophysiology, Harbin Medical University, Harbin 150086 (China); Fu Songbin [Department of Genetics, Harbin Medical University, Harbin 150086 (China); Bio-pharmaceutical Key Laboratory of Heilongjiang Province, Harbin 150086 (China); Lu Fanghao [Department of Pathophysiology, Harbin Medical University, Harbin 150086 (China)]. E-mail: lufanghao1973@yahoo.com.cn; Wu Bo [Department of Pathophysiology, Harbin Medical University, Harbin 150086 (China); Gong Dongmei [Department of Pharmacology, Harbin Medical University, Harbin 150086 (China); Pan, Zhen-wei [Department of Pharmacology, Harbin Medical University, Harbin 150086 (China); Lv Yanjie [Department of Pharmacology, Harbin Medical University, Harbin 150086 (China); Zhao Yajun [Department of Pathophysiology, Harbin Medical University, Harbin 150086 (China); Li Quanfeng [Department of Pathophysiology, Harbin Medical University, Harbin 150086 (China); Wang Rui [Department of Pathophysiology, Harbin Medical University, Harbin 150086 (China); Department of Biology, Lakehead University, Thunder Bay, Ont., P7B5E1 (Canada); Yang Baofeng [Department of Pharmacology, Harbin Medical University, Harbin 150086 (China); Bio-pharmaceutical Key Laboratory of Heilongjiang Province, Harbin 150086 (China); Xu Changqing [Department of Pathophysiology, Harbin Medical University, Harbin 150086 (China) and Bio-pharmaceutical Key Laboratory of Heilongjiang Province, Harbin 150086 (China)]. E-mail: xucq@163.com

    2006-09-08T23:59:59.000Z

    The calcium-sensing receptor (CaR) is a seven-transmembrane G-protein coupled receptor, which activates intracellular effectors, for example, it causes inositol phosphate (IP) accumulation to increase the release of intracellular calcium. Although intracellular calcium overload has been implicated in the cardiac ischemia/reperfusion (I/R)-induced apoptosis, the role of CaR in the induction of apoptosis has not been fully understood. This study tested the hypothesis that CaR is involved in I/R cardiomyocyte apoptosis by increasing [Ca{sup 2+}]{sub i}. The isolated rat hearts were subjected to 40-min ischemia followed by 2 h of reperfusion, meanwhile GdCl{sub 3} was added to reperfusion solution. The expression of CaR increased at the exposure to GdCl{sub 3} during I/R. By laser confocal microscopy, it was observed that the intracellular calcium was significantly increased and exhibited a collapsed {delta}{psi} {sub m}, as monitored by 5,5',6,6'-tetrachloro-1,1',3,3'- tetraethylbenzimidazolcarbocyanine iodide (JC-1) during reperfusion with GdCl{sub 3}. Furthermore, the number of apoptotic cells was significantly increased as shown by TUNEL assay. Typical apoptotic cells were observed with transmission electron microscopy in I/R with GdCl{sub 3} but not in the control group. The expression of cytosolic cytochrome c and activated caspase-9 and caspase-3 was significantly increased whereas the expression of mitochondrial cytochrome c significantly decreased in I/R with GdCl{sub 3} in comparison to the control. In conclusion, these results suggest that CaR is involved in the induction of cardiomyocyte apoptosis during ischemia/reperfusion through activation of cytochrome c-caspase-3 signaling pathway.

  18. Musashi2 modulates K562 leukemic cell proliferation and apoptosis involving the MAPK pathway

    SciTech Connect (OSTI)

    Zhang, Huijuan; Tan, Shi; Wang, Juan; Chen, Shana; Quan, Jing; Xian, Jingrong; Zhang, Shuai shuai; He, Jingang; Zhang, Ling, E-mail: lingzhang@cqmu.edu.cn

    2014-01-01T23:59:59.000Z

    The RNA-binding protein Musashi2 (Msi2) has been identified as a master regulator within a variety of stem cell populations via the regulation of translational gene expression. A recent study has suggested that Msi2 is strongly expressed in leukemic cells of acute myeloid leukemia patients, and elevated Msi2 is associated with poor prognosis. However, the potential role of Msi2 in leukemogenesis is still not well understood. Here, we investigated the effect of Msi2 knockdown on the biological properties of leukemic cells. High expression of Msi2 was found in K562 and KG-1a leukemic cell lines, and low expression was observed in the U937 cell line. We transduced K562 cells with two independent adenoviral shRNA vectors targeting Msi2 and confirmed knockdown of Msi2 at the mRNA and protein levels. Msi2 silencing inhibited cell growth and caused cell cycle arrest by increasing the expression of p21 and decreasing the expression of cyclin D1 and cdk2. In addition, knockdown of Msi2 promoted cellular apoptosis via the upregulation of Bax and downregulation of Bcl-2 expression. Furthermore, Msi2 knockdown resulted in the inactivation of the ERK/MAPK and p38/MAPK pathways, but no remarkable change in p-AKT was observed. These data provide evidence that Msi2 plays an important role in leukemogenesis involving the MAPK signaling pathway, which indicates that Msi2 may be a novel target for leukemia treatment. - Highlights: • Knockdown of Msi2 inhibited K562 cell growth and arrested cell cycle progression. • Knockdown of Msi2 induced K562 cell apoptosis via the regulation of Bax and Bcl-2. • The MAPK pathway was involved in the process of Msi2-mediated leukemogenesis. • Our data indicate that Msi2 is a potential new target for leukemia treatment.

  19. The Orosomucoid 1 protein is involved in the vitamin D – mediated macrophage de-activation process

    SciTech Connect (OSTI)

    Gemelli, Claudia, E-mail: claudia.gemelli@unimore.it [Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 287, 41125 Modena (Italy); Center for Regenerative Medicine, University of Modena and Reggio Emilia, Via Gottardi 100, 41125 Modena (Italy); Martello, Andrea; Montanari, Monica; Zanocco Marani, Tommaso; Salsi, Valentina; Zappavigna, Vincenzo; Parenti, Sandra; Vignudelli, Tatiana; Selmi, Tommaso; Ferrari, Sergio; Grande, Alexis [Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 287, 41125 Modena (Italy)

    2013-12-10T23:59:59.000Z

    Orosomucoid 1 (ORM1), also named Alpha 1 acid glycoprotein A (AGP-A), is an abundant plasma protein characterized by anti-inflammatory and immune-modulating properties. The present study was designed to identify a possible correlation between ORM1 and Vitamin D3 (1,25(OH)2D3), a hormone exerting a widespread effect on cell proliferation, differentiation and regulation of the immune system. In particular, the data described here indicated that ORM1 is a 1,25(OH)2D3 primary response gene, characterized by the presence of a VDRE element inside the 1 kb sequence of its proximal promoter region. This finding was demonstrated with gene expression studies, Chromatin Immunoprecipitation and luciferase transactivation experiments and confirmed by VDR full length and dominant negative over-expression. In addition, several experiments carried out in human normal monocytes demonstrated that the 1,25(OH)2D3 – VDR – ORM1 pathway plays a functional role inside the macrophage de-activation process and that ORM1 may be considered as a signaling molecule involved in the maintenance of tissue homeostasis and remodeling. - Highlights: • ORM1 is a Vitamin D primary response gene. • VD and its receptor VDR are involved in the de-activation process mediated by human resident macrophages. • The signaling pathway VD-VDR-ORM1 plays an important role in the control of macrophage de-activation process. • ORM1 may be defined as a signaling molecule implicated in the maintenance of tissue homeostasis and remodeling.

  20. Action Selection and Mental Transformation Based on a Chain of Forward Models

    E-Print Network [OSTI]

    Hoffmann, Heiko

    are internal sensorimotor models that predict how the sensory situation changes as a result of an agent- motor models and specifically forward models are sup- posed to be involved. Wolpert et al. (2003) for using a chain of forward models for prediction). Instead of trying to model hu- mans or animals, we

  1. Kinetic model for nitric oxide formation during pulverized coal combustion

    SciTech Connect (OSTI)

    Mitchell, J.W.; Tarbell, J.M.

    1982-03-01T23:59:59.000Z

    A mathematical model of NO formation during pulverised coal combustion was developed from a proposed kinetic mechanism involving 12 overall chemical reactions. Most significantly, the model describes the complex conversion of coal bound nitrogen compounds to NO during combustion. The predictions of the model compare favourably with literature data and are in qualitative agreement with trends observed in practical coal combustion.

  2. Efficiently Mining Approximate Models of Associations in Evolving Databases

    E-Print Network [OSTI]

    Zaki, Mohammed Javeed

    and data mining has relied on devising efficient techniques to build accurate models from the data data mining purposes (where response time is often more important than model quality as long as model on is typically very large, and the tasks involved are inherently I/O intensive. Second, the computational demands

  3. Using Linear Genetic Programming to Develop a C/C++ Simulation Model of a Waste Incinerator. Larry M Deschaine PE

    E-Print Network [OSTI]

    Fernandez, Thomas

    /C++ computer simulation model that mimics the performance of the concentrations of carbon dioxide. It #12;involves variable input material properties (solids, liquids and gaseous), high temperature, large

  4. Optimal linear Glauber model

    E-Print Network [OSTI]

    Shaon Sahoo; Soumya Kanti Ganguly

    2015-02-01T23:59:59.000Z

    Contrary to the actual nonlinear Glauber model (NLGM), the linear Glauber model (LGM) is exactly solvable, although the detailed balance condition is not generally satisfied. This motivates us to address the issue of writing the transition rate ($w_j$) in a best possible linear form such that the mean squared error in satisfying the detailed balance condition is least. The advantage of this work is that, by studying the LGM analytically, we will be able to anticipate how the kinetic properties of an arbitrary Ising system depend on the temperature and the coupling constants. The analytical expressions for the optimal values of the parameters involved in the linear $w_j$ are obtained using a simple Moore-Penrose pseudoinverse matrix. This approach is quite general, in principle applicable to any system and can reproduce the exact results for one dimensional Ising system. In the continuum limit, we get a linear time-dependent Ginzburg-Landau (TDGL) equation from the Glauber's microscopic model of non-conservative dynamics. We analyze the critical and dynamic properties of the model, and show that most of the important results obtained in different studies can be reproduced by our new mathematical approach. We will also show in this paper that the effect of magnetic field can easily be studied within our approach; in particular, we show that the inverse of relaxation time changes quadratically with (weak) magnetic field and that the fluctuation-dissipation theorem is valid for our model.

  5. 6/6/2014 1 of 6 OHS 11-033 revision Animal Research Protocols Involving Hazardous Chemicals

    E-Print Network [OSTI]

    Kay, Mark A.

    OHS 11-033 revision Animal Research Protocols Involving Hazardous Chemicals I. OVERVIEW Hazardous Chemicals: Known or suspect carcinogens, reproductive toxins or other highly toxic substances (e. Reference the SU Chemical Hygiene Plan for hazardous chemical definitions. Potential Exposures: Research

  6. Interactions among College and University Faculty and Students Involved in Academic Student Organizations: An Analysis of Qualitative and Quantitative Engagement

    E-Print Network [OSTI]

    Holzweiss, Peggy Carol

    2011-10-21T23:59:59.000Z

    The purpose of this study was to describe what kind of student-faculty interactions are occurring in the context of academic student organizations as well as identify the quality and quantity of such interactions and what factors are involved...

  7. Supply chain management (SCM) involves the management of materials and information across the entire supply chain. This includes raw material

    E-Print Network [OSTI]

    Calgary, University of

    Supply chain management (SCM) involves the management of materials and information across this concentration will be required to take three core courses: Materials and Supply Chain Management, Transportation Purchasing identify global sources of materials, select vendors, and manage negotiati

  8. Talking about living and dying with the oldest old: public involvement in a study on end of life care in care homes.

    E-Print Network [OSTI]

    Goodman, Claire; Mathie, Elspeth; Cowe, Marion; Mendoza, Alex; Westwood, Daphne; Munday, Diane; Wilson, Patricia M; Crang, Clare; Froggatt, Katherine; Iliffe, Steve; Manthorpe, Jill; Gage, Heather; Barclay, Stephen

    2011-11-23T23:59:59.000Z

    , governance and safeguarding, and the discussion and interpretation of emergent findings with the older people living in the care homes. PPI as collaborators in the recruitment process Recruitment to the study was a staged process, that involved securing care... expressed doubts about participation Table 1 Public involvement in different stages of research process PIR Involvement Level of Involvement Study Design Input on grant proposal and development of method for public involvement within the study Steering...

  9. The Effects of an Intervention to Foster a Caring and Task-Involving Climate at a University Recreation Center

    E-Print Network [OSTI]

    Brown, Theresa Clare

    2011-04-21T23:59:59.000Z

    using constructs from the POMS (depression, anxiety, fearful, fatigue, hostility; Usala & 18 Hertzog, 1989). An advantage of the instruments selected is there flexibility for the researcher to 19 indicate time frame (Pressman & Cohen, 2005...-Being, Self-Assuredness, Attentiveness) 6 were positively related to the task-involving climate. All but fatigue of the negative mood states 7 (i.e., Depressed, Anxiety, Hostility, Fearful) were positively associated to the ego-involving 8 climate...

  10. Responses of Magnocellular Neurons to Osmotic Stimulation Involves Coactivation of Excitatory and Inhibitory Input: An

    E-Print Network [OSTI]

    Feng, Jianfeng

    of normal rats respond to intra- venous infusions of hypertonic saline with gradual, linear in- creases response to such infusions. We show that a simple computational model can reproduce these responses well, but only if it is assumed that hypertonic infusions coacti- vate excitatory and inhibitory synaptic inputs

  11. NJITMAGA-HARDCOPY Some of those involved in the public policy debate may have

    E-Print Network [OSTI]

    Bieber, Michael

    customers and protecting con- sumers from the full impact of skyrocketing costs of natural gas and other competing economic models. Those of us in the business, however, never lost sight of the fact, cleaner technologies. Competitive electric markets are still developing. The process is more advanced

  12. Parabolic equation solution of seismo-acoustics problems involving variations in bathymetry and sediment thickness

    E-Print Network [OSTI]

    , Troy, New York 12180 Finn B. Jensen and Mario Zampolli NATO Undersea Research Center, 19126 La Spezia solutions. We also apply the approach to a model problem based on a complex environment off the New Jersey to outgoing and incoming energy. These factors give rise to the parabolic wave equations7 r ur w = ± i L-1 M 1

  13. Uniqueness of Solutions to Single-Stage Isobaric Flash Processes Involving

    E-Print Network [OSTI]

    Lucia, Angelo

    of material stability, the Gibbs-Duhem equation, and the Cauchy interlace theorem. Results for the other solutions. Solution curves for the energy balance equation (for the QP case) and the vapor specification. The question of uniqueness arises because the set of model equations that describeseparation processes

  14. R-Axion: A New LHC Physics Signature Involving Muon Pairs

    SciTech Connect (OSTI)

    Goh, Hock-Seng; /UC, Berkeley /LBL, Berkeley; Ibe, Masahiro; /SLAC

    2012-04-12T23:59:59.000Z

    In a class of models with gauge mediated supersymmetry breaking, the existence of a light pseudo scalar particle, R-axion, with a mass in hundreds MeV range is predicted. The striking feature of such a light R-axion is that it mainly decays into a pair of muons and leaves a displaced vertex inside detectors once it is produced. In this talk, we show how we can search for the R-axion at the coming LHC experiments. The one main goal of the LHC experiments is discovering supersymmetry which has been anticipated for a long time to solve the hierarchy problem. Once the supersymmetric standard model (SSM) is confirmed experimentally, the next question is how the supersymmetry is broken and how the effects of symmetry breaking are mediated to the SSM sector. In most cases, such investigations on 'beyond the SSM physics' rely on arguments based on extrapolations of the observed supersymmetry mass parameters to higher energies. However, there is one class of models of supersymmetry breaking where we can get a direct glimpse of the structure of the hidden sector with the help of the R-symmetry. The R-symmetry plays an important role in rather generic models of spontaneous supersymmetry breaking. At the same time, however, it must be broken in some way in order for the gauginos in the SSM sector to have non-vanishing masses. One possibility of the gaugino mass generation is to consider models where the gaugino masses are generated as a result of the explicit breaking of the R-symmetries. Unfortunately, in those models, the R-symmetry leaves little trace for the collider experiments, since the mass of the R-axion is typically heavy and beyond the reach of the LHC experiments. In this talk, instead, we consider a class of models with gauge mediation where the R-symmetry in the hidden/messenger sectors is exact in the limit of the infinite reduced Planck scale, i.e. M{sub PL} {yields} {infinity}. In this case, the gaugino masses are generated only after the R-symmetry is broken spontaneously. We also assume that the R-symmetry is respected by the SSM sector as well as the origin of the higgsino mass {mu} and the Higgs mass mixing B{mu} at the classical level. We call this scenario, the minimal R-symmetry breaking scenario.

  15. Spred2 is involved in imatinib-induced cytotoxicity in chronic myeloid leukemia cells

    SciTech Connect (OSTI)

    Liu, Xiao-Yun; Yang, Yue-Feng; Wu, Chu-Tse; Xiao, Feng-Jun; Zhang, Qun-Wei [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China)] [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China); Ma, Xiao-Ni [Lanzhou University of Technology, Lanzhou 730050 (China)] [Lanzhou University of Technology, Lanzhou 730050 (China); Li, Qing-Fang; Yan, Jun [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China)] [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China); Wang, Hua, E-mail: wanghualjh@gmail.com [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China)] [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China); Wang, Li-Sheng, E-mail: wangls@nic.bmi.ac.cn [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China)] [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China)

    2010-03-19T23:59:59.000Z

    Spreds, a recently established class of negative regulators of the Ras-ERK (extracellular signal-regulated kinase) pathway, are involved in hematogenesises, allergic disorders and tumourigenesis. However, their role in hematologic neoplasms is largely unknown. Possible effects of Spreds on other signal pathways closely related to Ras-ERK have been poorly investigated. In this study, we investigated the in vitro effects of Spred2 on chronic myeloid leukemia (CML) cells. In addition to inhibiting the well-established Ras-ERK cascade, adenovirus-mediated Spred2 over-expression inhibits constitutive and stem cell factor (SCF)-stimulated sphingosine kinase-1 (SPHK1) and Mcl-1 expression, as well as inhibiting proliferation and inducing apoptosis in CML cells. In K562 cells and primary CML cells, imatinib induces endogenous Spred2 expression. Spred2 silencing by stable RNA interference partly protects K562 cells against imatinib-induced apoptosis. Together, these data implicate Spred2 in imatinib-induced cytotoxicity in CML cells, possibly by inhibiting the Ras-ERK cascade and the pro-survival signaling molecules SPHK1 and Mcl-1. These findings reveal potential targets for selective therapy of CML.

  16. Depletion of bovine pituitary prolactin by cysteamine involves a thiol:disulfide mechanism

    SciTech Connect (OSTI)

    Lorenson, M.Y.; Jacobs, L.S.

    1984-10-01T23:59:59.000Z

    Cysteamine (2-aminoethanethiol (CySH)) reduces measurable PRL concentrations in vivo and in vitro. Since secretion is also inhibited, CySH may block conversion from a poorly assayable hormone storage form(s) to readily assayable, releasable PRL. This would represent a previously unrecognized mechanism for secretory regulation. We undertook the present study to identify the sites involved in the loss of measurable PRL (depletion) induced by cysteamine. The disulfide cystamine was ineffective on secretory granules unless combined with reduced glutathione, indicating the generation of the active CySH-thiol form. Pretreatment of granules with thiol-blocking agents resulted in dose-dependent enhancement of CySH inhibition, achieving nearly complete inhibition with 5 mM iodoacetamide. In contrast, pretreatment with reduced glutathione or dithiothreitol, respectively, impaired or abolished the CySH effect. These data suggest that the mechanism by which CySH causes PRL depletion is mediated by granule disulfides and the -SH of CySH. The regulation of thiol:disulfide equilibria appears to be an important determinant of the detectability of PRL storage forms and of their secretion.

  17. Identification of a Xylogalacturonan Xylosyltransferase Involved in Pectin Biosynthesis in Arabidopsis

    SciTech Connect (OSTI)

    Pauly, Markus; Sorensen, Susanne Oxenboll; Harholt, Jesper; Geshi, Naomi; Sakuragi, Yumiko; Moller, Isabel; Zandleven, Joris; Bernal, Adriana J.; Jensen, Niels Bjerg; Sorensen, Charlotte; Jensen, Jacob K.; Beldman, Gerrit; Willats, William G.T.; Scheller, Henrik

    2009-08-19T23:59:59.000Z

    Xylogalacturonan (XGA) is a class of pectic polysaccharide found in plant cell walls. The Arabidopsis thaliana locus At5g33290 encodes a predicted Type II membrane protein, and insertion mutants of the At5g33290 locus had decreased cell wall xylose. Immunological studies, enzymatic extraction of polysaccharides, monosaccharide linkage analysis, and oligosaccharide mass profiling were employed to identify the affected cell wall polymer. Pectic XGA was reduced to much lower levels in mutant than in wild-type leaves, indicating a role of At5g33290 in XGA biosynthesis. The mutated gene was designated xylogalacturonan deficient1 (xgd1). Transformation of the xgd1-1 mutant with the wild-type gene restored XGA to wild-type levels. XGD1 protein heterologously expressed in Nicotiana benthamiana catalyzed the transfer of xylose from UDP-xylose onto oligogalacturonides and endogenous acceptors. The products formed could be hydrolyzed with an XGA-specific hydrolase. These results confirm that the XGD1 protein is a XGA xylosyltransferase. The protein was shown by expression of a fluorescent fusion protein in N. benthamiana to be localized in the Golgi vesicles as expected for a glycosyltransferase involved in pectin biosynthesis.

  18. From public participation to stakeholder involvement: The rocky road to more inclusiveness

    SciTech Connect (OSTI)

    Peelle, E.

    1995-07-01T23:59:59.000Z

    Surviving always at the edge of extinction, public participation in environmental decision making has an uncertain and problematic history. From its emergence from the urban planning and delivery system efforts of the 1960s to many siting and non-siting uses today, it remains a battleground, with few successes and many failures. While some compelling structural, organizational and cultural explanations for this state of affairs exist, the author offers a further one--a too-limited definition and vision of public participation. One then can argue for a more inclusive process such as stakeholder involvement (SI) to enable a more viable approach to decision making. One can argue that the narrow conceptualization offered in the term public participation (PP) is partly responsible for the meager results of decades of efforts by earnest practitioners. Because of the limited, unique, and self-selected publics that respond to the major PP mechanisms such as public hearings, PP has become largely the province of organized activist groups and is largely accepted as such by most parties, including PP professionals. The author reviews the roles of Congress, federal agencies/proponents, local governments, activist groups and PP professionals in creating the current limited PP processes. She discusses trends and prospects for moving to broader based, more inclusive SI approaches. The emerging SI approach presents major methodological and organizational challenges, but offers the promise of outcomes more likely to be legitimated and potentially more lasting.

  19. Effect of short-term exposure to dichlorvos on synaptic plasticity of rat hippocampal slices: Involvement of acylpeptide hydrolase and {alpha}{sub 7} nicotinic receptors

    SciTech Connect (OSTI)

    Olmos, Cristina; Sandoval, Rodrigo [Laboratory of Environmental Neurotoxicology, Department of Biomedical Sciences, Faculty of Medicine, Universidad Catolica del Norte, Larrondo 1281, 178-1421 Coquimbo (Chile); Rozas, Carlos [Laboratory of Neurosciences, Department of Biology, Faculty of Chemistry and Biology, Universidad de Santiago de Chile, Alameda 3363, Santiago (Chile); Navarro, Sebastian [Laboratory of Environmental Neurotoxicology, Department of Biomedical Sciences, Faculty of Medicine, Universidad Catolica del Norte, Larrondo 1281, 178-1421 Coquimbo (Chile); Wyneken, Ursula [Laboratory of Neurosciences, Faculty of Medicine, Universidad de Los Andes, San Carlos de Apoquindo 2200, Santiago (Chile); Zeise, Marc [School of Psychology, Faculty of Humanities, University of Santiago de Chile, Alameda 3363, Santiago (Chile); Morales, Bernardo [Laboratory of Neurosciences, Department of Biology, Faculty of Chemistry and Biology, Universidad de Santiago de Chile, Alameda 3363, Santiago (Chile); Pancetti, Floria [Laboratory of Environmental Neurotoxicology, Department of Biomedical Sciences, Faculty of Medicine, Universidad Catolica del Norte, Larrondo 1281, 178-1421 Coquimbo (Chile)], E-mail: pancetti@ucn.cl

    2009-07-01T23:59:59.000Z

    Dichlorvos is the active molecule of the pro-drug metrifonate used to revert the cognitive deficits associated with Alzheimer's disease. A few years ago it was reported that dichlorvos inhibits the enzyme acylpeptide hydrolase at lower doses than those necessary to inhibit acetylcholinesterase to the same extent. Therefore, the aim of our investigation was to test the hypothesis that dichlorvos can enhance synaptic efficacy through a mechanism that involves acylpeptide hydrolase instead of acetylcholinesterase inhibition. We used long-term potentiation induced in rat hippocampal slices as a model of synaptic plasticity. Our results indicate that short-term exposures (20 min) to 50 {mu}M dichlorvos enhance long-term potentiation in about 200% compared to the control condition. This effect is correlated with approximately 60% inhibition of acylpeptide hydrolase activity, whereas acetylcholinesterase activity remains unaffected. Paired-pulse facilitation and inhibition experiments indicate that dichlorvos does not have any presynaptic effect in the CA3 {yields} CA1 pathway nor affect gabaergic interneurons. Interestingly, the application of 100 nM methyllicaconitine, an {alpha}{sub 7} nicotinic receptor antagonist, blocked the enhancing effect of dichlorvos on long-term potentiation. These results indicate that under the exposure conditions described above, dichlorvos enhances long-term potentiation through a postsynaptic mechanism that involves (a) the inhibition of the enzyme acylpeptide hydrolase and (b) the modulation of {alpha}{sub 7} nicotinic receptors.

  20. Fermionic Models with Superconducting Circuits

    E-Print Network [OSTI]

    U. Las Heras; L. García-Álvarez; A. Mezzacapo; E. Solano; L. Lamata

    2015-03-31T23:59:59.000Z

    We propose a method for the efficient quantum simulation of fermionic systems with superconducting circuits. It consists in the suitable use of Jordan-Wigner mapping, Trotter decomposition, and multiqubit gates, be with the use of a quantum bus or direct capacitive couplings. We apply our method to the paradigmatic cases of 1D and 2D Fermi-Hubbard models, involving couplings with nearest and next-nearest neighbours. Furthermore, we propose an optimal architecture for this model and discuss the benchmarking of the simulations in realistic circuit quantum electrodynamics setups.

  1. Chemical kinetics and combustion modeling

    SciTech Connect (OSTI)

    Miller, J.A. [Sandia National Laboratories, Livermore, CA (United States)

    1993-12-01T23:59:59.000Z

    The goal of this program is to gain qualitative insight into how pollutants are formed in combustion systems and to develop quantitative mathematical models to predict their formation rates. The approach is an integrated one, combining low-pressure flame experiments, chemical kinetics modeling, theory, and kinetics experiments to gain as clear a picture as possible of the process in question. These efforts are focused on problems involved with the nitrogen chemistry of combustion systems and on the formation of soot and PAH in flames.

  2. Fermionic Models with Superconducting Circuits

    E-Print Network [OSTI]

    U. Las Heras; L. García-Álvarez; A. Mezzacapo; E. Solano; L. Lamata

    2014-11-10T23:59:59.000Z

    We propose a method for the efficient quantum simulation of fermionic systems with superconducting circuits. It consists in the suitable use of Jordan-Wigner mapping, Trotter decomposition, and multiqubit gates, be with the use of a quantum bus or direct capacitive couplings. We apply our method to the paradigmatic cases of 1D and 2D Fermi-Hubbard models, involving couplings with nearest and next-nearest neighbours. Furthermore, we propose an optimal architecture for this model and discuss the benchmarking of the simulations in realistic circuit quantum electrodynamics setups.

  3. Influence Of Recruitment Methods On Couple Involvement In Transition To Parenthood Intervention

    E-Print Network [OSTI]

    Coca, Vanessa Albina

    2009-09-30T23:59:59.000Z

    controlled trials. Journal of Consulting and Clinical Psychology, 73, 6-14. Schulz, M. S., Cowan, C. P., & Cowan, P. A. (2006). Promoting healthy beginnings: A randomized controlled trial of a preventive intervention to preserve marital quality... of a brief version of the dyadic adjustment scale with a nonparametric item analysis model. Psychological Assessment, 17, 15-27. Shadish, W. R., & Baldwin, S. A. (2005). Effects of behavioral marital therapy: A meta- analysis of randomized...

  4. Lifecycle Model

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1997-05-21T23:59:59.000Z

    This chapter describes the lifecycle model used for the Departmental software engineering methodology.

  5. Investigations of the Fundamental Surface Reactions Involved in the Sorption and Desorption of Radionuclides

    SciTech Connect (OSTI)

    Czerwinski, Ken; Heske, Clemens; Moser, Duane; Misra, Mnoranjan; McMillion, Glen

    2011-04-20T23:59:59.000Z

    Models for describing solution- and surface-phase reactions have been used for 30 years, but only recently applicable to complex surfaces. Duff et al., using micro-XANES, found that Pu was concentrated on Mn-oxide and smectite phases of zeolitic tuff, providing an evaluation of contaminant speciation on surfaces for modeling. Experiments at Los Alamos demonstrated that actinides display varying surface residence time distributions, probably reflective of mineral surface heterogeneity. We propose to investigate the sorption/desorption behavior of radionuclides from mineral surfaces, as effected by microorganisms, employing isolates from Nevada Test Site deep alluvium as a model system. Characterizations will include surface area, particle size distribution, x-ray diffraction (XRD), microprobe analysis, extractions, and microbiology. Surface interactions will be assessed by electron spectroscopy (XPS), x-ray absorption fine structure spectroscopy (XAFS), X-ray emission spectroscopy, transmission electron microscopy (TEM) and Scanning electron microscopy (SEM). Desert Research Institute (DRI), University of Nevada, Reno (UNR), and University of Nevada, Las Vegas (UNLV) researchers will collaborate to enhance scientific infrastructure and the understanding of contaminant behavior on surfaces, with broader implications for the management of DOE sites.

  6. Combining Modeling and Gaming for Predictive Analytics

    SciTech Connect (OSTI)

    Riensche, Roderick M.; Whitney, Paul D.

    2012-08-22T23:59:59.000Z

    Many of our most significant challenges involve people. While human behavior has long been studied, there are recent advances in computational modeling of human behavior. With advances in computational capabilities come increases in the volume and complexity of data that humans must understand in order to make sense of and capitalize on these modeling advances. Ultimately, models represent an encapsulation of human knowledge. One inherent challenge in modeling is efficient and accurate transfer of knowledge from humans to models, and subsequent retrieval. The simulated real-world environment of games presents one avenue for these knowledge transfers. In this paper we describe our approach of combining modeling and gaming disciplines to develop predictive capabilities, using formal models to inform game development, and using games to provide data for modeling.

  7. A supersymmetric model for graphene

    E-Print Network [OSTI]

    Everton M. C. Abreu; Marco A. De Andrade; Leonardo P. G. de Assis; Jose A. Helayel-Neto; A. L. M. A. Nogueira; Ricardo C. Paschoal

    2014-07-21T23:59:59.000Z

    In this work, we focus on the fermionic structure of the low-energy excitations of graphene (a monolayer of carbon atoms) to propose a new supersymmetric field-theoretic model for this physical system. In the current literature, other proposals for describing graphene physics have been contemplated at the level of supersymmetric quantum mechanics. Also, by observing the inhomogeneities between neighbor carbon atoms, Jackiw {\\it et al.} have set up an interesting chiral Abelian gauge theory. We show in this paper that our formulation encompasses models discussed previously as sectors of an actually richer (supersymmetric) planar gauge model. Possible interpretations for the fields involved in the present graphene model are proposed and the question of supersymmetry breaking is discussed.

  8. Symposium: Micro & Nano Fluidics 2014 Nanotech 2014 (17th) Conference History

    E-Print Network [OSTI]

    Oh, Kwang W.

    | Photonic Materials & Devices | Soft Matter and Colloids | Bio Nano Materials | Nanostructured Coatings Infrastructure | Modeling & Simulation at the Nanoscale | Carbon Nano Structures & Devices Advanced Materials & NEMS Devices & Applications | Organic, Flexible and Printed Electronics | Photonic Materials & Devices

  9. Distributed Generation Potential of the U.S. Commercial Sector

    E-Print Network [OSTI]

    LaCommare, Kristina Hamachi; Edwards, Jennifer L.; Gumerman, Etan; Marnay, Chris

    2005-01-01T23:59:59.000Z

    GPRA NEMS O&M R&D Annual Energy Outlook combined heat andnotably the Annual Energy Outlook (AEO). EIA’s forecasts areto produce the Annual Energy Outlook (AEO), and model runs

  10. Hot Water Distribution System Model Enhancements

    SciTech Connect (OSTI)

    Hoeschele, M.; Weitzel, E.

    2012-11-01T23:59:59.000Z

    This project involves enhancement of the HWSIM distribution system model to more accurately model pipe heat transfer. Recent laboratory testing efforts have indicated that the modeling of radiant heat transfer effects is needed to accurately characterize piping heat loss. An analytical methodology for integrating radiant heat transfer was implemented with HWSIM. Laboratory test data collected in another project was then used to validate the model for a variety of uninsulated and insulated pipe cases (copper, PEX, and CPVC). Results appear favorable, with typical deviations from lab results less than 8%.

  11. Cosmological models in the nonsymmetric Kaluza-Klein Theory

    E-Print Network [OSTI]

    M. W. Kalinowski

    2003-12-30T23:59:59.000Z

    We consider a dynamics of Higgs' field in the framework of cosmological models involving the scalar field from Nonsymmetric Kaluza-Klein (Jordan-Thiry) Theory. The field plays here a role of a quintessence field. We consider phase transition in cosmological models of the second and of the first order due to evolution of Higgs' field. We developed inflationary models including calculation of an amount of inflation. We match some cosmological models, calculating a Hubble parameter and an age of the Universe.

  12. Modeling Control Mechanisms with Normative Multiagent Systems

    E-Print Network [OSTI]

    van der Torre, Leon

    of renewable energy. We apply a conceptual model based on normative multiagent systems (NMAS). We propose to stimulate the production of #12;energy from renewable sources [20]. The ruling involves an obligation for energy sup- pliers to produce evidence of having distributed a certain minimal amount of renewable energy

  13. EPSRC CASE Studentship Statistical Modelling of Fingerprints

    E-Print Network [OSTI]

    Oakley, Jeremy

    and mathematics together with experience or strong interest in statistical computing (including programming in R1 EPSRC CASE Studentship Statistical Modelling of Fingerprints SUMMARY This CASE studentship involves working with researchers in the Statistics & Interpretation Group of the Forensic Science Service

  14. MODELING OF ALUMINUM NANOPARTICLE FORMATION R. Schefflan

    E-Print Network [OSTI]

    MODELING OF ALUMINUM NANOPARTICLE FORMATION R. Schefflan D. Kalyon S. Kovenklioglu Stevens Picatinny Arsenal's process for making alumina coated nanoparticles of aluminum involves the conversion of gaseous aluminum, in the presence of helium carrier gas, to solid nanoparticles and their subsequent

  15. A look at the ocean in the EC-Earth climate model Andreas Sterl Richard Bintanja Laurent Brodeau Emily Gleeson

    E-Print Network [OSTI]

    Haak, Hein

    to the special issue on EC-Earth, a global climate and earth system model based on the seasonal forecast system-011-1239-2 #12;phytoplankton) processes are involved. To study such complex interactions, Earth System Models

  16. Modeling Harry's Brook Watershed Alexandra Konings, REU 2006 Tracing the Water

    E-Print Network [OSTI]

    Petta, Jason

    for Undergraduates, 2006 #12;Modeling Harry's Brook Watershed Alexandra Konings, REU 2006 Urban Hydrology Water's Storm Water Management Model (SWMM) Solves differential and algebraic equations involved in calculatingModeling Harry's Brook Watershed Alexandra Konings, REU 2006 Tracing the Water: Detailed Modeling

  17. Public Involvement Plan Public Involvement Plan

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOn April 23, 2014, an OHASeptember 2010 |ofDepartment ofPart 1021 | DepartmentofAPublic

  18. TRISO Fuel Performance: Modeling, Integration into Mainstream Design Studies, and Application to a Thorium-fueled Fusion-Fission Hybrid Blanket

    E-Print Network [OSTI]

    Powers, Jeffrey

    2011-01-01T23:59:59.000Z

    Models and Methodologies incineration [49, 51, 57]. Duringlater in life. The incineration phase involves operation atoperation ends and incineration phase operation begins, on

  19. Application of the SCALE TSUNAMI Tools for the Validation of Criticality Safety Calculations Involving 233U

    SciTech Connect (OSTI)

    Mueller, Don [ORNL; Rearden, Bradley T [ORNL; Hollenbach, Daniel F [ORNL

    2009-02-01T23:59:59.000Z

    The Radiochemical Development Facility at Oak Ridge National Laboratory has been storing solid materials containing 233U for decades. Preparations are under way to process these materials into a form that is inherently safe from a nuclear criticality safety perspective. This will be accomplished by down-blending the {sup 233}U materials with depleted or natural uranium. At the request of the U.S. Department of Energy, a study has been performed using the SCALE sensitivity and uncertainty analysis tools to demonstrate how these tools could be used to validate nuclear criticality safety calculations of selected process and storage configurations. ISOTEK nuclear criticality safety staff provided four models that are representative of the criticality safety calculations for which validation will be needed. The SCALE TSUNAMI-1D and TSUNAMI-3D sequences were used to generate energy-dependent k{sub eff} sensitivity profiles for each nuclide and reaction present in the four safety analysis models, also referred to as the applications, and in a large set of critical experiments. The SCALE TSUNAMI-IP module was used together with the sensitivity profiles and the cross-section uncertainty data contained in the SCALE covariance data files to propagate the cross-section uncertainties ({Delta}{sigma}/{sigma}) to k{sub eff} uncertainties ({Delta}k/k) for each application model. The SCALE TSUNAMI-IP module was also used to evaluate the similarity of each of the 672 critical experiments with each application. Results of the uncertainty analysis and similarity assessment are presented in this report. A total of 142 experiments were judged to be similar to application 1, and 68 experiments were judged to be similar to application 2. None of the 672 experiments were judged to be adequately similar to applications 3 and 4. Discussion of the uncertainty analysis and similarity assessment is provided for each of the four applications. Example upper subcritical limits (USLs) were generated for application 1 based on trending of the energy of average lethargy of neutrons causing fission, trending of the TSUNAMI similarity parameters, and use of data adjustment techniques.

  20. Probabilities of delayed processes for nuclei involved in the r-process

    SciTech Connect (OSTI)

    Panov, I. V., E-mail: Igor.Panov@itep.ru [Institute for Theoretical and Experimental Physics (Russian Federation); Korneev, I. Yu.; Lutostansky, Yu. S. [National Research Center Kurchatov Institute (Russian Federation)] [National Research Center Kurchatov Institute (Russian Federation); Thielemann, F.-K. [University of Basel, Institute of Physics (Switzerland)] [University of Basel, Institute of Physics (Switzerland)

    2013-01-15T23:59:59.000Z

    Delayed fission, along with induced and spontaneous fission, is responsible for the suppression of the production of superheavy elements both during the r-process and after its completion. Beta-decay strength functions are required for calculating delayed fission. In the present study, respective strength functions are calculated by relying on the theory of finite Fermi systems and by predominantly employing nuclear masses and fission barriers predicted by a generalized Thomas-Fermi model. The probabilities for delayed fission and for the emission of delayed neutrons are calculated for a number of isotopes. On the basis of calculations performed in order to determine the probabilities for delayed processes, it is shown that some of the delayed-fission probabilities calculated thus far were substantially overestimated. The application of these new results to calculating the r-process may change substantially both the r-process path and the yields of superheavy nuclei.

  1. Four-photon spectroscopy of ultrathin nickel films involving picosecond biharmonic pumping

    SciTech Connect (OSTI)

    Petnikova, V M; Rudenko, K V; Shuvalov, Vladimir V [International Laser Center, M. V. Lomonosov Moscow State University, Moscow (Russian Federation)

    1999-07-31T23:59:59.000Z

    Ultrathin (5 - 25 nm thick) nickel films were investigated experimentally by the picosecond biharmonic pumping method. Characteristic side resonances in the wing of the dependence of the self-diffraction efficiency on the frequency detuning of the biharmonic pumping components were observed. A model of the electronic part of the cubic nonlinear susceptibility was constructed. It takes into account the real structure of the spectrum of the electronic states of nickel, its quantum-size renormalisation and spin splitting, interband and intraband relaxation, as well as selection rules for the electronic transitions. For interband polarisation relaxation times T{sub 2} > 300 fs, a qualitative agreement was obtained between the calculated relationships and the experimental data. In the frequency-degenerate case, points at which the nonlinear response should be absent were found on the frequency scale. (this issue is dedicated to the memory of s a akhmanov)

  2. A new development in microcomputer software for mine ventilation planning involving the installation of fans

    SciTech Connect (OSTI)

    O'Leary, M.S.J.; McPherson, M.J.

    1989-01-01T23:59:59.000Z

    This paper introduces a computer simulation that extends the use of microcomputer systems for mine ventilation planning. The program was developed as part of an ongoing study to produce a simulation model that would determine the optimum duties of a main fan and a booster fan without requiring the trial-and-error runs that are necessary with currently available programs. To use the new program, the user specifies the location of one main fan and one booster fan, and the minimum required airflows in any number of working places. The computer determines the fan duties that maintains the required airflows at the lowest operating costs without causing undesired recirculation. The methodology of the program and an example showing how it can be applied are presented.

  3. ORIGINAL PAPER Modeling of Thermal-Assisted Dislocation Friction

    E-Print Network [OSTI]

    Marks, Laurence D.

    ORIGINAL PAPER Modeling of Thermal-Assisted Dislocation Friction Y. Liao · L. D. Marks Received: 25+Business Media, LLC 2009 Abstract We generalize a model for friction at a sliding interface involving the motion of thermally activated friction. Going further, we suggest a plausible method for generalizing the fric- tional

  4. Facilitating Communication with Open Learner Models: A Semiotic Engineering Perspective

    E-Print Network [OSTI]

    Bull, Susan

    , communication, multiple users. 1 Introduction Open learner models (OLM) are learner models that are accessible by users. We here consider the multiple users of OLMs at school level. We envisage that communication around OLMs will not only be of the 'classic' computer-user type, but will increas- ingly involve the OLM

  5. Modelling precipitation of niobium carbide in austenite: multicomponent diffusion, capillarity,

    E-Print Network [OSTI]

    Cambridge, University of

    Modelling precipitation of niobium carbide in austenite: multicomponent diffusion, capillarity, and coarsening N. Fujita and H. K. D. H. Bhadeshia The growth of niobium carbide in austenite involves the diffusion of both niobium and carbon. These elements diffuse at very different rates. A model is presented

  6. A Geometric Construction of Traveling Waves in a Bioremediation Model

    E-Print Network [OSTI]

    Beck, Margaret

    A Geometric Construction of Traveling Waves in a Bioremediation Model M. Beck , A. Doelman , T. J email: mabeck@math.bu.edu Abstract Bioremediation is a promising technique for cleaning contam- inated groundwater and soil. We study a bioremediation model involving a substrate (contaminant to be removed

  7. Global trade in dairy products involves complex and con-tentious issues. Viewed broadly from the perspective of

    E-Print Network [OSTI]

    Radeloff, Volker C.

    Global trade in dairy products involves complex and con- tentious issues. Viewed broadly from the perspective of "society," there are large benefits from liberalizing trade. Viewed narrowly from the perspective of dairy producers, liberalized trade is desirable only if it expands exports and reduces imports

  8. Project Brief: These works, part of the project to complete the RSM and Bessemer Buildings, involve refurbishment of level 3

    E-Print Network [OSTI]

    Project Brief: These works, part of the project to complete the RSM and Bessemer Buildings, involve London and acts as a focus for interdisciplinary research into nanoscale materials. It attracts academics in this field, fuelled by the prospect of a new generation of high performance materials with applications

  9. Abstract--Network security against possible attacks involves making decisions under uncertainty. Not only may one be

    E-Print Network [OSTI]

    ], security in wireless networks [12], [13] and cyber-security [14], [15], [16]. In [17] the readers can find1 Abstract--Network security against possible attacks involves making decisions under uncertainty for a further DDoS (Distributed Denial of Service) botnet attack on servers). Due to limited defense

  10. Abstract --The growth of non-conventional renewable energies involves a new challenge for optimal network expansion. A better

    E-Print Network [OSTI]

    Catholic University of Chile (Universidad Católica de Chile)

    1 Abstract -- The growth of non-conventional renewable energies involves a new challenge and implementation of policies to develop Non-Conventional Renewable Energies (NCRE), they can be seen as a mechanism for optimal network expansion. A better integration of renewables will be allowed by determining transmission

  11. Japan, EU adamant about their proposals to host ITER, put off negotiations to next year; Joint construction plan involving Japan,

    E-Print Network [OSTI]

    Japan, EU adamant about their proposals to host ITER, put off negotiations to next year; Joint construction plan involving Japan, U.S. South Korea also emerging NIHON KEIZAI, December 20, 2004 Japan are likely to enter a crucial stage early in the next year. In addition to Japan and the EU, the United

  12. Involvement of Extracellular Signal-Regulated Kinase (ERK) in Pardaxin-Induced Dopamine Release from PC12 Cells

    E-Print Network [OSTI]

    Linial, Michal

    Involvement of Extracellular Signal-Regulated Kinase (ERK) in Pardaxin-Induced Dopamine Release kinase (ERK)/mitogen-activated protein kinase (MAPK) in pardaxin-induced dopamine (DA) release DA release. Time course exper- iments indicated that PX, at nontoxic concentrations, stimu- lated ERK

  13. Transportation of Dangerous Goods Anyone involved with the Transportation of Dangerous Goods must be trained. This includes shipping

    E-Print Network [OSTI]

    TDG Transportation of Dangerous Goods Anyone involved with the Transportation of Dangerous Goods must be trained. This includes shipping and receiving. All receiving of Dangerous Goods for the Science in Departmental Offices or labs. How do you know if the package is a dangerous goods shipment? Parcels containing

  14. 162 Electrical and Computer Engineering 163 Courses and projects that actively involve them in their own education and

    E-Print Network [OSTI]

    Richards-Kortum, Rebecca

    162 Electrical and Computer Engineering 163 · Courses and projects that actively involve them · A broad education outside of engineering and science that emphasizes the role of electrical and computer of technology Graduate and undergraduate programs in electrical and computer engineering offer concentrations

  15. What is Your Environmental Wellness? The environmental dimension involves accepting the impact we have on our world and doing something

    E-Print Network [OSTI]

    sprays. _____ 7. I do not litter. _____ 8. I volunteer my time for environmental conservation projectsWhat is Your Environmental Wellness? The environmental dimension involves accepting the impact we points _____ 1. I consciously conserve energy (electricity, heat, light, water, etc.) in my place

  16. CER4 Encodes an Alcohol-Forming Fatty Acyl-Coenzyme A Reductase Involved in Cuticular Wax Production

    E-Print Network [OSTI]

    Kunst, Ljerka

    CER4 Encodes an Alcohol-Forming Fatty Acyl-Coenzyme A Reductase Involved in Cuticular Wax surfaces of land plants. It is composed of a cutin polymer matrix and waxes. Cuticular waxes are complex and characterization of CER4, a wax bio- synthetic gene from Arabidopsis (Arabidopsis thaliana). Arabidopsis cer4

  17. TERC Research in the Chilean Patagonia TERC is involved in a collaborative research effort with the EULA Center of the

    E-Print Network [OSTI]

    Schladow, S. Geoffrey

    TERC Research in the Chilean Patagonia TERC is involved in a collaborative research effort of the Chilean Patagonia. The lakes, rivers, glaciers, wetlands and other aquatic environments of the Chilean Patagonia offer a globally unique opportunity for science. They represent the most undisturbed aquatic

  18. Control of Major-Accident Hazards Involving Land Transmission Charlotte BOUISSOU, Project Manager for Pipelines Risk Assessment

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    aims to help authorities to balance the requirement of the new pipeline regulation with regardsControl of Major-Accident Hazards Involving Land Transmission Pipelines Charlotte BOUISSOU, Project Manager for Pipelines Risk Assessment Sandrine DESCOURRIERE, Project Manager for Plants Risk Assessment

  19. Abstract--This paper reports on studies involving brain-machine interfaces (BMIs) that provide near-instantaneous

    E-Print Network [OSTI]

    Guenther, Frank

    Abstract--This paper reports on studies involving brain- machine interfaces (BMIs) that provide output. I. INTRODUCTION ECENT years have seen the development of brain- machine interfaces (BMIs or electroencephalography (EEG). In the current paper we focus on a specific subset of brain-machine interfaces: those aimed

  20. Development and application of a hybrid method involving interpolation and ab initio calculations for the determination of transition states

    E-Print Network [OSTI]

    Bell, Alexis T.

    optimization P-RFO method. Such methods tend to work well if information about the potential energy surfaceDevelopment and application of a hybrid method involving interpolation and ab initio calculations scheme was used to estimate the energy and gradient, thereby reducing the calls to the quantum mechanical

  1. Enhanced Postischemic Functional Recovery in CYP2J2 Transgenic Hearts Involves Mitochondrial ATP-Sensitive K

    E-Print Network [OSTI]

    Hammock, Bruce D.

    Enhanced Postischemic Functional Recovery in CYP2J2 Transgenic Hearts Involves Mitochondrial ATP, Bruce D. Hammock, Elizabeth Murphy, Darryl C. Zeldin Abstract--Human CYP2J2 is abundant in heart and its eicosanoid products in the heart remains unknown. Transgenic mice with cardiomyocyte

  2. Most fish have a forward undulatory swimming mechanism that involves a kinematic propulsive wave travelling down the

    E-Print Network [OSTI]

    D'Août, Kristiaan

    Most fish have a forward undulatory swimming mechanism that involves a kinematic propulsive wave backwards in a similar way. We compared the kinematics (wave speed, cycle frequency, amplitude, local in the direction opposite to that of swimming. We observe two major kinematic differences. First, the slope of wave

  3. A Lipid-modified Phosphoinositide-specific Phospholipase C (TcPI-PLC) Is Involved in Differentiation of Trypomastigotes to

    E-Print Network [OSTI]

    Singer, Randall

    A Lipid-modified Phosphoinositide-specific Phospholipase C (TcPI-PLC) Is Involved C (PI- PLC) is an important component of the inositol phos- phate/diacylglycerol signaling pathway. A newly discov- ered Trypanosoma cruzi PI-PLC (TcPI-PLC) is lipid modified in its N terminus, targeted

  4. Nonadiabatic dynamics for processes involving multiple avoided curve crossings: Double proton transfer and proton-coupled electron transfer

    E-Print Network [OSTI]

    Hammes-Schiffer, Sharon

    Nonadiabatic dynamics for processes involving multiple avoided curve crossings: Double proton transfer and proton-coupled electron transfer reactions Jian-Yun Fang and Sharon Hammes June 1997; accepted 26 August 1997 The extension of the surface hopping method ``molecular dynamics

  5. Thomas Meyer Basic Infobase Change Abstract. Generalisations of theory change involving arbitrary sets of w s instead of

    E-Print Network [OSTI]

    Meyer, Tommie

    Thomas Meyer Basic Infobase Change Abstract. Generalisations of theory change involving arbitrary these lines by Meyer et al. 15]. We take an infobase as a nite sequence of w s, with each element Kluwer Academic Publishers. Printed in the Netherlands. #12;216 T. Meyer In this paper we propose a form

  6. Using Software Development Standards to Analyse Accidents Involving Electrical, Electronic or Programmable, Electronic Systems: The Blade Mill PLC Case Study

    E-Print Network [OSTI]

    Johnson, Chris

    -1- Using Software Development Standards to Analyse Accidents Involving Electrical, Electronic developed by the US Department of Energy (1992). The intention is that both the lightweight flowcharts's (HSE) mission is to ensure that risks to people's health and safety from work activities are properly

  7. Optimization-based Design of Plant-Friendly Input Signals for Model-on-Demand Estimation and Model Predictive Control

    E-Print Network [OSTI]

    Mittelmann, Hans D.

    is shown by applying it to a case study involving composition control of a binary distillation column. I is demonstrated in a binary high-purity distillation column case study by Weischedel and McAvoy [7], a demandingOptimization-based Design of Plant-Friendly Input Signals for Model-on-Demand Estimation and Model

  8. Climate change scenario planning in Alaska's National Parks: Stakeholder involvement in the decision-making process

    SciTech Connect (OSTI)

    Ernst, Kathleen M [ORNL] [ORNL; Van Riemsdijk, Dr. Micheline [University of Tennessee (UT)] [University of Tennessee (UT)

    2013-01-01T23:59:59.000Z

    This article studies the participation of stakeholders in climate change decision-making in Alaska s National Parks. We place stakeholder participation within literatures on environmental and climate change decision-making. We conducted participant observation and interviews in two planning workshops to investigate the decision-making process, and our findings are three-fold. First, the inclusion of diverse stakeholders expanded climate change decision-making beyond National Park Service (NPS) institutional constraints. Second, workshops of the Climate Change Scenario Planning Project (CCSPP) enhanced institutional understandings of participants attitudes towards climate change and climate change decision-making. Third, the geographical context of climate change influences the decisionmaking process. As the first regional approach to climate change decision-making within the NPS, the CCSPP serves as a model for future climate change planning in public land agencies. This study shows how the participation of stakeholders can contribute to robust decisions, may move climate change decision-making beyond institutional barriers, and can provide information about attitudes towards climate change decision-making.

  9. Climate Change Scenario Planning in Alaska's National Parks: Stakeholder Involvement in the Decision-Making Process

    SciTech Connect (OSTI)

    Ernst, Kathleen M [ORNL] [ORNL; Van Riemsdijk, Dr. Micheline [University of Tennessee (UT)] [University of Tennessee (UT)

    2013-01-01T23:59:59.000Z

    This article studies the participation of stakeholders in climate change decision-making in Alaska s National Parks. We place stakeholder participation within literatures on environmental and climate change decision-making. We conducted participant observation and interviews in two planning workshops to investigate the decision-making process, and our findings are three-fold. First, the inclusion of diverse stakeholders expanded climate change decision-making beyond National Park Service (NPS) institutional constraints. Second, workshops of the Climate Change Scenario Planning Project (CCSPP) enhanced institutional understandings of participants attitudes towards climate change and climate change decision-making. Third, the geographical context of climate change influences the decision-making process. As the first regional approach to climate change decision-making within the NPS, the CCSPP serves as a model for future climate change planning in public land agencies. This study shows how the participation of stakeholders can contribute to robust decisions, may move climate change decision-making beyond institutional barriers, and can provide information about attitudes towards climate change decision-making.

  10. Maturity Model for Advancing Smart Grid Interoperability

    SciTech Connect (OSTI)

    Knight, Mark; Widergren, Steven E.; Mater, J.; Montgomery, Austin

    2013-10-28T23:59:59.000Z

    Abstract—Interoperability is about the properties of devices and systems to connect and work properly. Advancing interoperability eases integration and maintenance of the resulting interconnection. This leads to faster integration, lower labor and component costs, predictability of projects and the resulting performance, and evolutionary paths for upgrade. When specifications are shared and standardized, competition and novel solutions can bring new value streams to the community of stakeholders involved. Advancing interoperability involves reaching agreement for how things join at their interfaces. The quality of the agreements and the alignment of parties involved in the agreement present challenges that are best met with process improvement techniques. The GridWise® Architecture Council (GWAC) sponsored by the United States Department of Energy is supporting an effort to use concepts from capability maturity models used in the software industry to advance interoperability of smart grid technology. An interoperability maturity model has been drafted and experience is being gained through trials on various types of projects and community efforts. This paper describes the value and objectives of maturity models, the nature of the interoperability maturity model and how it compares with other maturity models, and experiences gained with its use.

  11. Ventilation Model

    SciTech Connect (OSTI)

    H. Yang

    1999-11-04T23:59:59.000Z

    The purpose of this analysis and model report (AMR) for the Ventilation Model is to analyze the effects of pre-closure continuous ventilation in the Engineered Barrier System (EBS) emplacement drifts and provide heat removal data to support EBS design. It will also provide input data (initial conditions, and time varying boundary conditions) for the EBS post-closure performance assessment and the EBS Water Distribution and Removal Process Model. The objective of the analysis is to develop, describe, and apply calculation methods and models that can be used to predict thermal conditions within emplacement drifts under forced ventilation during the pre-closure period. The scope of this analysis includes: (1) Provide a general description of effects and heat transfer process of emplacement drift ventilation. (2) Develop a modeling approach to simulate the impacts of pre-closure ventilation on the thermal conditions in emplacement drifts. (3) Identify and document inputs to be used for modeling emplacement ventilation. (4) Perform calculations of temperatures and heat removal in the emplacement drift. (5) Address general considerations of the effect of water/moisture removal by ventilation on the repository thermal conditions. The numerical modeling in this document will be limited to heat-only modeling and calculations. Only a preliminary assessment of the heat/moisture ventilation effects and modeling method will be performed in this revision. Modeling of moisture effects on heat removal and emplacement drift temperature may be performed in the future.

  12. Thermodynamic model for mineral solubility in aqueous fluids: theory, calibration and application to model

    E-Print Network [OSTI]

    Manning, Craig

    describes the energetics of solvation more accurately than does the Born electrostatic theory and can be extended beyond the limits of experimental measurements of the dielectric constant of H2O. The new model, their dissolution energet- ics involve a relatively small contribution from the solvent volumetric properties

  13. Model Selection for the Competing-Risks Model With and Without Masking

    E-Print Network [OSTI]

    Lee, Chun Man "Thomas"

    Department of Statistics Colorado State University Fort Collins, CO 80523-1877 (tlee@stat.colostate.edu) The competing-risks model is useful in settings in which individuals (or units) may die (or fail) because for competing-risks data with and without masking involves the specification of cause-specific hazard rates

  14. Moist multi-scale models for the hurricane embryo

    SciTech Connect (OSTI)

    Majda, Andrew J. [New York University; Xing, Yulong [ORNL; Mohammadian, Majid [University of Ottawa, Canada

    2010-01-01T23:59:59.000Z

    Determining the finite-amplitude preconditioned states in the hurricane embryo, which lead to tropical cyclogenesis, is a central issue in contemporary meteorology. In the embryo there is competition between different preconditioning mechanisms involving hydrodynamics and moist thermodynamics, which can lead to cyclogenesis. Here systematic asymptotic methods from applied mathematics are utilized to develop new simplified moist multi-scale models starting from the moist anelastic equations. Three interesting multi-scale models emerge in the analysis. The balanced mesoscale vortex (BMV) dynamics and the microscale balanced hot tower (BHT) dynamics involve simplified balanced equations without gravity waves for vertical vorticity amplification due to moist heat sources and incorporate nonlinear advective fluxes across scales. The BMV model is the central one for tropical cyclogenesis in the embryo. The moist mesoscale wave (MMW) dynamics involves simplified equations for mesoscale moisture fluctuations, as well as linear hydrostatic waves driven by heat sources from moisture and eddy flux divergences. A simplified cloud physics model for deep convection is introduced here and used to study moist axisymmetric plumes in the BHT model. A simple application in periodic geometry involving the effects of mesoscale vertical shear and moist microscale hot towers on vortex amplification is developed here to illustrate features of the coupled multi-scale models. These results illustrate the use of these models in isolating key mechanisms in the embryo in a simplified content.

  15. Ventilation Model

    SciTech Connect (OSTI)

    V. Chipman

    2002-10-05T23:59:59.000Z

    The purpose of the Ventilation Model is to simulate the heat transfer processes in and around waste emplacement drifts during periods of forced ventilation. The model evaluates the effects of emplacement drift ventilation on the thermal conditions in the emplacement drifts and surrounding rock mass, and calculates the heat removal by ventilation as a measure of the viability of ventilation to delay the onset of peak repository temperature and reduce its magnitude. The heat removal by ventilation is temporally and spatially dependent, and is expressed as the fraction of heat carried away by the ventilation air compared to the fraction of heat produced by radionuclide decay. One minus the heat removal is called the wall heat fraction, or the remaining amount of heat that is transferred via conduction to the surrounding rock mass. Downstream models, such as the ''Multiscale Thermohydrologic Model'' (BSC 2001), use the wall heat fractions as outputted from the Ventilation Model to initialize their post-closure analyses. The Ventilation Model report was initially developed to analyze the effects of preclosure continuous ventilation in the Engineered Barrier System (EBS) emplacement drifts, and to provide heat removal data to support EBS design. Revision 00 of the Ventilation Model included documentation of the modeling results from the ANSYS-based heat transfer model. The purposes of Revision 01 of the Ventilation Model are: (1) To validate the conceptual model for preclosure ventilation of emplacement drifts and verify its numerical application in accordance with new procedural requirements as outlined in AP-SIII-10Q, Models (Section 7.0). (2) To satisfy technical issues posed in KTI agreement RDTME 3.14 (Reamer and Williams 2001a). Specifically to demonstrate, with respect to the ANSYS ventilation model, the adequacy of the discretization (Section 6.2.3.1), and the downstream applicability of the model results (i.e. wall heat fractions) to initialize post-closure thermal models (Section 6.6). (3) To satisfy the remainder of KTI agreement TEF 2.07 (Reamer and Williams 2001b). Specifically to provide the results of post-test ANSYS modeling of the Atlas Facility forced convection tests (Section 7.1.2). This portion of the model report also serves as a validation exercise per AP-SIII.10Q, Models, for the ANSYS ventilation model. (4) To further satisfy KTI agreements RDTME 3.01 and 3.14 (Reamer and Williams 2001a) by providing the source documentation referred to in the KTI Letter Report, ''Effect of Forced Ventilation on Thermal-Hydrologic Conditions in the Engineered Barrier System and Near Field Environment'' (Williams 2002). Specifically to provide the results of the MULTIFLUX model which simulates the coupled processes of heat and mass transfer in and around waste emplacement drifts during periods of forced ventilation. This portion of the model report is presented as an Alternative Conceptual Model with a numerical application, and also provides corroborative results used for model validation purposes (Section 6.3 and 6.4).

  16. Macro-System Model: A Federated Object Model for Cross-Cutting Analysis of Hydrogen Production, Delivery, Consumption and Associated Emissions; Preprint

    SciTech Connect (OSTI)

    Ruth, M.; Diakov, V.; Goldsby, M. E.; Sa, T. J.

    2010-12-01T23:59:59.000Z

    It is commonly accepted that the introduction of hydrogen as an energy carrier for light-duty vehicles involves concomitant technological development of infrastructure elements, such as production, delivery, and consumption, all associated with certain emission levels. To analyze these at a system level, the suite of corresponding models developed by the United States Department of Energy and involving several national laboratories is combined in one macro-system model (MSM). The macro-system model is being developed as a cross-cutting analysis tool that combines a set of hydrogen technology analysis models. Within the MSM, a federated simulation framework is used for consistent data transfer between the component models. The framework is built to suit cross-model as well as cross-platform data exchange and involves features of 'over-the-net' computation.

  17. Structural system identification: Structural dynamics model validation

    SciTech Connect (OSTI)

    Red-Horse, J.R.

    1997-04-01T23:59:59.000Z

    Structural system identification is concerned with the development of systematic procedures and tools for developing predictive analytical models based on a physical structure`s dynamic response characteristics. It is a multidisciplinary process that involves the ability (1) to define high fidelity physics-based analysis models, (2) to acquire accurate test-derived information for physical specimens using diagnostic experiments, (3) to validate the numerical simulation model by reconciling differences that inevitably exist between the analysis model and the experimental data, and (4) to quantify uncertainties in the final system models and subsequent numerical simulations. The goal of this project was to develop structural system identification techniques and software suitable for both research and production applications in code and model validation.

  18. Wind Technology Modeling Within the System Advisor Model (SAM) (Poster)

    SciTech Connect (OSTI)

    Blair, N.; Dobos, A.; Ferguson, T.; Freeman, J.; Gilman, P.; Whitmore, J.

    2014-05-01T23:59:59.000Z

    This poster provides detail for implementation and the underlying methodology for modeling wind power generation performance in the National Renewable Energy Laboratory's (NREL's) System Advisor Model (SAM). SAM's wind power model allows users to assess projects involving one or more large or small wind turbines with any of the detailed options for residential, commercial, or utility financing. The model requires information about the wind resource, wind turbine specifications, wind farm layout (if applicable), and costs, and provides analysis to compare the absolute or relative impact of these inputs. SAM is a system performance and economic model designed to facilitate analysis and decision-making for project developers, financers, policymakers, and energy researchers. The user pairs a generation technology with a financing option (residential, commercial, or utility) to calculate the cost of energy over the multi-year project period. Specifically, SAM calculates the value of projects which buy and sell power at retail rates for residential and commercial systems, and also for larger-scale projects which operate through a power purchase agreement (PPA) with a utility. The financial model captures complex financing and rate structures, taxes, and incentives.

  19. The molecular mechanisms involved in the genetic instability of the CCTG. CAGG repeats associated with myotonic dystrophy type 2

    E-Print Network [OSTI]

    Dere, Ruhee J.

    2006-08-16T23:59:59.000Z

    THE MOLECULAR MECHANISMS INVOLVED IN THE GENETIC INSTABILITY OF THE CCTG?CAGG REPEATS ASSOCIATED WITH MYOTONIC DYSTROPHY TYPE 2 A Dissertation by RUHEE J. DERE Submitted to the Office of Graduate Studies of Texas A&M University... TYPE 2 A Dissertation by RUHEE J. DERE Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements for the degree...

  20. Exploring the Behavioral and Psychological Differences between Male and Female Youth with a History of Fire Involvement

    E-Print Network [OSTI]

    Morris, Ed M.

    2014-08-31T23:59:59.000Z

    . While it is supported that fire-involved youth tend to be males, recent statistics published by the National Fire Protection Association (NFPA) indicated sex differences in the type of fires set. Specifically, the NFPA report found that female youth... expression and found it surprising that females were associated with covert emotional expression through firesetting behavior because they are typically socialized to express emotions overtly. If the female-dominated structure fires documented by NFPA...

  1. Examining students' perceptions of study abroad programs involving sport through application of the social cognitive career theory

    E-Print Network [OSTI]

    Jones, Gregory C.

    2009-06-02T23:59:59.000Z

    OF SCIENCE Approved by: Chair of Committee, George B. Cunningham Committee Members, Michael Sagas Ben Welch Head of Department, Steve Dorman August 2006 Major Subject: Kinesiology iii ABSTRACT Examining Students...? Perceptions of Study Abroad Programs Involving Sport Through Application of the Social Cognitive Career Theory. (August 2006) Gregory C. Jones, B.S., Sam Houston State University Chair of Advisory Committee: Dr. George B. Cunningham With sport...

  2. The effects of ego-involvement with the task upon the self-esteem/task performance relationship

    E-Print Network [OSTI]

    Nilles, Carol Anne

    1983-01-01T23:59:59.000Z

    study by Cottrell (1965). Not all of the research results involving task-speci- fic self-esteem have supported Korman's consistency theo- ry, however, As previously mentioned, several studies have yielded only partial support. Cohen and Lefkowitz... are motivated to maintain consistency between their self-esteem and their task performance (Korman, 1970). The research evidence re- garding this contention has generally been mixed. While numerous studies have provided support for Korman's con- sistency...

  3. Conversion of DAP models to SPEEDUP

    SciTech Connect (OSTI)

    Aull, J.E.

    1993-08-01T23:59:59.000Z

    Several processes at the Savannah River Site are modeled using Bechtel`s Dynamic Analysis Program (DAP) which uses a sequential modular modeling architecture. The feasibility of conversion of DAP models to SPEEDUP was examined because of the benefits associated with this de facto industry standard. The equation-based approach used in SPEEDUP gives accuracy, stability, and ease of maintenance. The DAP licenses on our site are for single-user PS/2 machines whereas the SPEEDUP product is licensed on a VAX minicomputer which provides faster execution and ease of integration with existing visualization tools. In this paper the basic unit operations of a DAP model that simulates a ventilation system are described. The basic operations were modeled with both DAP and SPEEDUP, and the two models yield results that are in close agreement. Since the basic unit operations of the DAP model have been successfully duplicated using SPEEDUP, it is feasible to proceed with model conversion. DAP subroutines and functions that involve only algebraic manipulation may be inserted directly into the SPEEDUP model or their underlying equations may be extracted and written as SPEEDUP model equations. A problem modeled in SPEEDUP running on a VAX 8810 runs approximately fifteen times faster in elapsed time than the same problem modeled with DAP on a 33 MHz Intel 80486 processor.

  4. Test models for improving filtering with model errors through stochastic parameter estimation

    SciTech Connect (OSTI)

    Gershgorin, B. [Department of Mathematics and Center for Atmosphere and Ocean Science, Courant Institute of Mathematical Sciences, New York University, NY 10012 (United States); Harlim, J. [Department of Mathematics, North Carolina State University, NC 27695 (United States)], E-mail: jharlim@ncsu.edu; Majda, A.J. [Department of Mathematics and Center for Atmosphere and Ocean Science, Courant Institute of Mathematical Sciences, New York University, NY 10012 (United States)

    2010-01-01T23:59:59.000Z

    The filtering skill for turbulent signals from nature is often limited by model errors created by utilizing an imperfect model for filtering. Updating the parameters in the imperfect model through stochastic parameter estimation is one way to increase filtering skill and model performance. Here a suite of stringent test models for filtering with stochastic parameter estimation is developed based on the Stochastic Parameterization Extended Kalman Filter (SPEKF). These new SPEKF-algorithms systematically correct both multiplicative and additive biases and involve exact formulas for propagating the mean and covariance including the parameters in the test model. A comprehensive study is presented of robust parameter regimes for increasing filtering skill through stochastic parameter estimation for turbulent signals as the observation time and observation noise are varied and even when the forcing is incorrectly specified. The results here provide useful guidelines for filtering turbulent signals in more complex systems with significant model errors.

  5. Future climate trends from a first-difference atmospheric carbon dioxide regression model involving emissions scenarios for business as usual and for peak fossil fuel

    E-Print Network [OSTI]

    Leggett, L M W

    2014-01-01T23:59:59.000Z

    This paper investigates the implications of the future continuation of the demonstrated past (1960-2012) strong correlation between first-difference atmospheric CO2 and global surface temperature. It does this, for the period from the present to 2050, for a comprehensive range of future global fossil fuel energy use scenarios. The results show that even for a business-as-usual (the mid-level IPCC) fossil fuel use estimate, global surface temperature will rise at a slower rate than for the recent period 1960-2000. Concerning peak fossil fuel, for the most common scenario the currently observed (1998-2013)temperature plateau will turn into a decrease. The observed trend to date for temperature is compared with that for global climate disasters: these peaked in 2005 and are notably decreasing. The temperature and disaster results taken together are consistent with either a reduced business-as-usual fossil fuel use scenario into the future, or a peak fossil fuel scenario, but not with the standard business-as-usu...

  6. Sandia Energy - Systems Modeling

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Simulation Model Energy, Power & Water Simulation Model SunCity Model Water, Energy and Carbon Sequestration Model Gila Basin-Az Water Settlement Model Electrical Grid Storage...

  7. Modeling and design of compact microwave components and systems for wireless communications and power transmission

    E-Print Network [OSTI]

    Zepeda, Paola

    2004-09-30T23:59:59.000Z

    The contribution of the work here presented involves three main topics: Wireless Power Transmission (WPT) technology, phased array systems, and microwave components design and modeling. The first topic presents the conceptual design of a WPT system...

  8. Mathematical Modelling and Numerical Analysis Will be set by the publisher Modelisation Mathematique et Analyse Numerique

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    of underground storage facilities for nuclear waste. The processes involved in near-field models are extremely field u : [0, T ] × R3 and a pressure field p : [0, T ] × R such that - ·(u) + b p = f, in [0

  9. Reliable Phase Stability Analysis for Asymmetric Models , William D. Haynes2*

    E-Print Network [OSTI]

    Stadtherr, Mark A.

    ; Interval analysis; Validated computing; Equation of state; NRTL. * Current address: NFS Inc., 1205 Banner several examples, involving as many as eight components, with NRTL as the liquid phase model and a cubic

  10. The Pugh Controlled Convergence Method: Model-Based Evaluation and Implications for Design Theory

    E-Print Network [OSTI]

    Wijnia, Ype

    This paper evaluates the Pugh Controlled Convergence method and its relationship to recent developments in design theory. Computer executable models are proposed simulating a team of people involved in iterated cycles of ...

  11. Exploring a capability-demand interaction model for inclusive design evaluation

    E-Print Network [OSTI]

    Persad, Umesh

    2012-03-06T23:59:59.000Z

    of supporting analytical design evaluation for Inclusive Design. The analytical evaluation process involves evaluating products with user data rather than testing with actual users. The work focuses on the exploration of a capability-demand model of product...

  12. Mesoscale modeling of electrical percolation in fiber-filled systems Sameer S. Rahatekar and Marc Hamm

    E-Print Network [OSTI]

    Elliott, James

    Mesoscale modeling of electrical percolation in fiber-filled systems Sameer S. Rahatekar and Marc online 4 October 2005 The research described in this paper primarily involves mesoscale simulations

  13. Mathematical Model Reformulation for Lithium-Ion Battery Simulations: Galvanostatic Boundary Conditions

    E-Print Network [OSTI]

    Subramanian, Venkat

    Mathematical Model Reformulation for Lithium-Ion Battery Simulations: Galvanostatic Boundary of physics-based lithium-ion battery models to improve computational efficiency. While the additional steps, 2008. Published January 30, 2009. Mathematical modeling of lithium-ion batteries involves

  14. MicroScale Modeling of an AnodeSupported Planar Solid Oxide Fuel Cell

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    1 Micro­Scale Modeling of an Anode­Supported Planar Solid Oxide Fuel Cell P. Chinda1 , W. Wechsatol A micro ­ scale model of a Solid Oxide Fuel Cell (SOFC) involving the mass transfer together the available literatures. Keywords: Solid Oxide Fuel Cells, Micro ­ Scale Model, Mass Transfer, Electrochemical

  15. A Systematic Method for the Intentional Modelling and Verification of Business

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    A Systematic Method for the Intentional Modelling and Verification of Business Applications I appears to be a good candidate for involving business people in the early modelling of business applications, reducing the risk of business-IT systems misalignment. Furthermore, in the context of Model

  16. A Model-driven Approach to Designing Cross-enterprise Business Processes

    E-Print Network [OSTI]

    Bauer, Bernhard

    A Model-driven Approach to Designing Cross- enterprise Business Processes Bernhard Bauer1, Jörg P.p.mueller@siemens.com Abstract. Modeling and managing business processes that span multiple or- ganizations involves new for interoperability. In this paper, we present an approach to modeling cross-enterprise business processes based

  17. Modeling Quality Information within Business Process Models

    E-Print Network [OSTI]

    Paech, Barbara

    Modeling Quality Information within Business Process Models Robert Heinrich, Alexander Kappe. Business process models are a useful means to document information about structure and behavior literature and tool survey on modeling quality information within business process models. Keywords: Business

  18. Modeling Arcs

    SciTech Connect (OSTI)

    Insepov, Z.; Norem, J. [Argonne National Lab, Argonne, IL 60439 (United States); Vetizer, S.; Mahalingam, S. [Tech-X Corp., Boulder, CO (United States)

    2011-12-23T23:59:59.000Z

    Although vacuum arcs were first identified over 110 years ago, they are not yet well understood. We have since developed a model of breakdown and gradient limits that tries to explain, in a self-consistent way: arc triggering, plasma initiation, plasma evolution, surface damage and gradient limits. We use simple PIC codes for modeling plasmas, molecular dynamics for modeling surface breakdown, and surface damage, and mesoscale surface thermodynamics and finite element electrostatic codes for to evaluate surface properties. Since any given experiment seems to have more variables than data points, we have tried to consider a wide variety of arcing (rf structures, e beam welding, laser ablation, etc.) to help constrain the problem, and concentrate on common mechanisms. While the mechanisms can be comparatively simple, modeling can be challenging.

  19. Programming models

    SciTech Connect (OSTI)

    Daniel, David J [Los Alamos National Laboratory; Mc Pherson, Allen [Los Alamos National Laboratory; Thorp, John R [Los Alamos National Laboratory; Barrett, Richard [SNL; Clay, Robert [SNL; De Supinski, Bronis [LLNL; Dube, Evi [LLNL; Heroux, Mike [SNL; Janssen, Curtis [SNL; Langer, Steve [LLNL; Laros, Jim [SNL

    2011-01-14T23:59:59.000Z

    A programming model is a set of software technologies that support the expression of algorithms and provide applications with an abstract representation of the capabilities of the underlying hardware architecture. The primary goals are productivity, portability and performance.

  20. LEDCOM Model

    Broader source: Energy.gov [DOE]

    Zip file containing the LEDCOM model as an excel worksheet, the backend database, and an operating information document. Extract all files to the same local directory on your computer.

  1. Proceedings of the ASME 2011 Pacific Rim Technical Conference and Exhibition on Packaging and Integration of Electronic and Photonic Systems,MEMS and NEMS

    E-Print Network [OSTI]

    Lee, Hsien-Hsin "Sean"

    nearly 13% -18% cooling energy. INTRODUCTION Internet-based services supplied by companies like Ama- zon depends on many factors, including power distribution, thermal load and conse- quent cooling costs the efficiency of both cooling and power usage, across and within racks. To help implement spatially aware load

  2. The Yanks are Coming Over There: The Role of Anglo-Saxonism and American Involvement in the First World War

    E-Print Network [OSTI]

    Buenviaje, Dino Ejercito

    2014-01-01T23:59:59.000Z

    introduced the bondage of feudalism. This also coincidedcorrupted by Norman feudalism and continental absolutism. Bythe ideal model for the feudalism that was established since

  3. THE NGA-DOE GRANT TO EXAMINE CRITICAL ISSUES RELATED TO RADIOACTIVE WASTE AND MATERIALS DISPOSITION INVOLVING DOE FACILITIES

    SciTech Connect (OSTI)

    Ann M. Beauchesne

    2000-01-01T23:59:59.000Z

    Through the National Governors Association (NGA) project ``Critical Issues Related to Radioactive Waste and Materials Disposition Involving DOE Facilities'' NGA brings together Governors' policy advisors, state regulators, and DOE officials to examine critical issues related to the cleanup and operation of DOE nuclear weapons and research facilities. Topics explored through this project include: Decisions involving disposal of mixed, low-level, and transuranic (TRU) waste and disposition of nuclear materials; Decisions involving DOE budget requests and their effect on environmental cleanup and compliance at DOE facilities; Strategies to treat mixed, low-level, and transuranic (TRU) waste and their effect on individual sites in the complex; Changes to the FFCA site treatment plans as a result of proposals in the Department's Accelerating Cleanup: Paths to Closure plan and contractor integration analysis; Interstate waste and materials shipments; and Reforms to existing RCRA and CERCLA regulations/guidance to address regulatory overlap and risks posed by DOE wastes. The overarching theme of this project is to help the Department improve coordination of its major program decisions with Governors' offices and state regulators and to ensure such decisions reflect input from these key state officials and stakeholders. This report summarizes activities conducted during the period from October 1, 1999 through January 31, 2000, under the NGA grant. The work accomplished by the NGA project team during the past three months can be categorized as follows: maintained open communication with DOE on a variety of activities and issues within the DOE environmental management complex; convened and facilitated the October 6--8 NGA FFCA Task Force Meeting in Oak Ridge, Tennessee; maintained communication with NGA Federal Facilities Compliance Task Force members regarding DOE efforts to formulate a configuration for mixed low-level waste and low-level treatment and disposal, external regulation of DOE; and continued to facilitate interactions between the states and DOE to develop a foundation for an ongoing substantive relationship between the Governors of key states and the Department.

  4. THE NGA-DOE GRANT TO EXAMINE CRITICAL ISSUES RELATED TO RADIOACTIVE WASTE AND MATERIALS DISPOSITION INVOLVING DOE FACILITIES

    SciTech Connect (OSTI)

    NONE

    1998-07-01T23:59:59.000Z

    Through the National Governors' Association (NGA) project ''Critical Issues Related to Radioactive Waste and Materials Disposition Involving DOE Facilities'' NGA brings together Governors' policy advisors, state regulators, and DOE officials to examine critical issues related to the cleanup and operation of DOE nuclear weapons and research facilities. Topics explored through this project include: Decisions involving disposal of mixed, low-level, and transuranic (TRU) waste and disposition of nuclear materials. Decisions involving DOE budget requests and their effect on environmental cleanup and compliance at DOE facilities. Strategies to treat mixed, low-level, and transuranic (TRU) waste and their effect on individual sites in the complex. Changes to the FFCA site treatment plans as a result of proposals in DOE's Accelerating Cleanup: Paths to Closure strategy and contractor integration analysis. Interstate waste and materials shipments. Reforms to existing RCRA and CERCLA regulations/guidance to address regulatory overlap and risks posed by DOE wastes. The overarching theme of this project is to help the Department improve coordination of its major program decisions with Governors' offices and state regulators and to ensure such decisions reflect input from these key state officials and stakeholders. This report summarizes activities conducted during the quarter from April 30, 1998 through June 30, 1998 under the NGA project. The work accomplished by the NGA project team during the past four months can be categorized as follows: maintained open communication with DOE on a variety of activities and issues within the DOE environmental management complex; and provided ongoing support to state-DOE interactions. maintained communication with NGA Federal Facilities Compliance Task Force members regarding DOE efforts to formulate a configuration for mixed low-level waste and low-level treatment and disposal, DOE's Environmental Management Budget, and DOE's proposed Intersite Discussions.

  5. Error handling strategies in multiphase inverse modeling

    SciTech Connect (OSTI)

    Finsterle, S.; Zhang, Y.

    2010-12-01T23:59:59.000Z

    Parameter estimation by inverse modeling involves the repeated evaluation of a function of residuals. These residuals represent both errors in the model and errors in the data. In practical applications of inverse modeling of multiphase flow and transport, the error structure of the final residuals often significantly deviates from the statistical assumptions that underlie standard maximum likelihood estimation using the least-squares method. Large random or systematic errors are likely to lead to convergence problems, biased parameter estimates, misleading uncertainty measures, or poor predictive capabilities of the calibrated model. The multiphase inverse modeling code iTOUGH2 supports strategies that identify and mitigate the impact of systematic or non-normal error structures. We discuss these approaches and provide an overview of the error handling features implemented in iTOUGH2.

  6. Factors involved in the seasonal and geographical regulation of diapause in the boll weevil, Anthonomus grandis Boheman

    E-Print Network [OSTI]

    Sterling, W. L

    1966-01-01T23:59:59.000Z

    FACTORS INVOLVED IN 'ZHE SEASONAL AND GEOGEAPNICAL EMQULATION OF DIAPAUSE Ill ttlL BOLL itl' 'VIL I~it&I UNOiliUG OtOtBDIB BOtlIIiBB A thesis by Ninfield Linsoln Sterling Submitted to the Qraduate College of Texas AM Universe. tp in Fartial... under tsy water in wxuc-bottom disseotion dishes. Elgtrae and hind wings were removed and disseotions maCe un4ex' a miorosooye at S0s image. Gne ohaxeoter used fox' the determination of 4iayause was Che hyyertroyhS of Che abdominal fat body...

  7. Use of a Trellis Device for Endovascular Treatment of Venous Thrombosis Involving a Duplicated Inferior Vena Cava

    SciTech Connect (OSTI)

    Saettele, Megan R., E-mail: SaetteleM@umkc.edu [University of Missouri, Kansas City, Department of Radiology, Saint Luke's Hospital (United States); Morelli, John N., E-mail: dr.john.morelli@gmail.com [Texas A and M University Health Science Center, Department of Radiology, Scott and White Clinic and Hospital (United States); Chesis, Paul; Wible, Brandt C. [University of Missouri, Kansas City, Department of Interventional Radiology, Saint Luke's Hospital (United States)] [University of Missouri, Kansas City, Department of Interventional Radiology, Saint Luke's Hospital (United States)

    2013-12-15T23:59:59.000Z

    Congenital anomalies of the inferior vena cava (IVC) are increasingly recognized with CT and venography techniques. Although many patients with IVC anomalies are asymptomatic, recent studies have suggested an association with venous thromboembolism. We report the case of a 62-year-old woman with extensive venous clot involving the infrarenal segment of a duplicated left IVC who underwent pharmacomechanical thrombectomy and tissue plasminogen activator catheter-directed thrombolysis with complete deep venous thrombosis resolution. To our knowledge this is the first reported case in the English literature of the use of a Trellis thrombectomy catheter in the setting of duplicated IVC.

  8. Dynamic Modeling of Cascading Failure in Power Systems

    E-Print Network [OSTI]

    Song, Jiajia; Ghanavati, Goodarz; Hines, Paul D H

    2014-01-01T23:59:59.000Z

    The modeling of cascading failure in power systems is difficult because of the many different mechanisms involved; no single model captures all of these mechanisms. Understanding the relative importance of these different mechanisms is an important step in choosing which mechanisms need to be modeled for particular types of cascading failure analysis. This work presents a dynamic simulation model of both power networks and protection systems, which can simulate a wider variety of cascading outage mechanisms, relative to existing quasi-steady state (QSS) models. The model allows one to test the impact of different load models and protections on cascading outage sizes. This paper describes each module of the developed dynamic model and demonstrates how different mechanisms interact. In order to test the model we simulated a batch of randomly selected $N-2$ contingencies for several different static load configurations, and found that the distribution of blackout sizes and event lengths from the proposed dynamic...

  9. Model systems This year's model

    E-Print Network [OSTI]

    Raines, Ronald T.

    @biochem.wisc.edu RTR received ScB degrees in chemistry and biology from the Massachusetts Institute of Technology that initially inspired the chemical simplification. In such cases, the later stages of model studies can seem

  10. Parent Involvement (Spanish) 

    E-Print Network [OSTI]

    Howard, Jeff W.

    2005-05-10T23:59:59.000Z

    producidas por el servicio de Extensi?n en el Internet: http://tcebookstore.org Los programas educativos del Servicio de Extensi?n Agr?cola de Texas est?n disponibles para todas las personas, sin distinci?n de raza, color, sexo, minusvalidez, religi?n, edad...

  11. Parent Involvement (Spanish)

    E-Print Network [OSTI]

    Howard, Jeff W.

    2005-05-10T23:59:59.000Z

    producidas por el servicio de Extensi?n en el Internet: http://tcebookstore.org Los programas educativos del Servicio de Extensi?n Agr?cola de Texas est?n disponibles para todas las personas, sin distinci?n de raza, color, sexo, minusvalidez, religi?n, edad...

  12. Involvement & Outreach

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > The Energy Materials Center atdiffusivities in mesopores |Business

  13. Involvement and Communication Committee.

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Science (SC)Integrated Codes | NationalCurriculum IntroductionInvestor and entrepreneurBudget

  14. Involvement and Communication Committee.

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Science (SC)Integrated Codes | NationalCurriculum IntroductionInvestor and

  15. Involvement and Communication Committee.

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Science (SC)Integrated Codes | NationalCurriculum IntroductionInvestor andPublic

  16. Involvement and Communication Committee.

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Science (SC)Integrated Codes | NationalCurriculum IntroductionInvestor andPublicTank Waste

  17. Commitment to Public Involvement

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville Power Administration would like submit the following commentsCurrent-Promotions015 NMMSS

  18. TPA Public Involvement Survey

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What'sis Taking Over Our InstagramStructureProposedPAGE Creating a Geologic Play BookEnergyTOj

  19. Involvement of VAMP-2 in exocytosis of IL-1{beta} in turbot (Scophthalmus maximus) leukocytes after Vibrio anguillarum infection

    SciTech Connect (OSTI)

    Chai Yingmei [Department of Life Science, Ocean University of China, Qingdao 266003 (China); Marine Bioactive Substances Laboratory, First Institute of Oceanography, SOA, Qingdao 266061 (China); College of Marine Life Sciences, Shandong University at Weihai, Weihai 264209 (China); Huang Xiaohang [Marine Bioactive Substances Laboratory, First Institute of Oceanography, SOA, Qingdao 266061 (China)]. E-mail: xiaohanghuang@yahoo.ca; Cong Bailin [Marine Bioactive Substances Laboratory, First Institute of Oceanography, SOA, Qingdao 266061 (China); Liu Shenghao [Marine Bioactive Substances Laboratory, First Institute of Oceanography, SOA, Qingdao 266061 (China); Chen Kui [Marine Bioactive Substances Laboratory, First Institute of Oceanography, SOA, Qingdao 266061 (China); Li Guangyou [Marine Bioactive Substances Laboratory, First Institute of Oceanography, SOA, Qingdao 266061 (China); Gaisano, Herbert Y. [Department of Medicine, University of Toronto, Toronto, M5S 1A8 (Canada)

    2006-04-07T23:59:59.000Z

    Vibrio anguillarum is a major pathogen threatening the fish aquaculture in China. Infection of cultivated turbot (Scophthalmus maximus) with V. anguillarum induced rapid synthesis and secretion of IL-1{beta}, which initiates the innate immune response. SNARE proteins are known to regulate vesicular trafficking and fusion in all eukaryotes. Here, we determined whether SNARE proteins, specifically vesicle-associated membrane protein-2 (VAMP-2), are involved in regulated exocytosis of IL-1{beta} of leukocytes in marine fish. We show that VAMP-2 is present in turbot blood leukocytes, with nucleotide sequence identity of 88.2% and 93.0% to those of zebra fish and sea bass, respectively. After Vibrio infection, turbot leukocyte VAMP-2 was increased at the levels of transcription and translation in a temporal pattern coinciding with leukocyte IL-1{beta} secretion. Confocal microscopy localized VAMP-2 to vesicle structures in leukocytes. Taken together, our results suggest that VAMP-2 is involved in regulated exocytosis of cytokines in immunocytes in fish.

  20. The negative cell cycle regulator, Tob (transducer of ErbB-2), is involved in motor skill learning

    SciTech Connect (OSTI)

    Wang Xinming [Laboratory of Higher Brain Functions, Institute of Neurobiology, Fudan University, 220 Han-Dan Road, Shanghai 200433 (China); Shanghai Institute of Physiology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031 (China); Gao Xiang [Laboratory of Molecular Cell Biology, Laboratory of Stem Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031 (China); Zhang Xuehan [Laboratory of Higher Brain Functions, Institute of Neurobiology, Fudan University, 220 Han-Dan Road, Shanghai 200433 (China); Tu Yanyang [Laboratory of Molecular Cell Biology, Laboratory of Stem Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031 (China); Jin Meilei [Research Center of Biotechnology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 500 Cao-Bao Road, Shanghai 200233 (China); Zhao Guoping [Chinese National Human Genome Center at Shanghai, 351 Guo-Shou-Jing Road, Zhang-Jiang Hi-Tech Park, Shanghai 201203 (China); Yu Lei [Department of Genetics and Center of Alcohol Studies, Rutgers University, 145 Bevier Road, Piscataway, NJ 08854 (United States); Jing Naihe [Laboratory of Molecular Cell Biology, Laboratory of Stem Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yue-Yang Road, Shanghai 200031 (China); Li Baoming [Laboratory of Higher Brain Functions, Institute of Neurobiology, Fudan University, 220 Han-Dan Road, Shanghai 200433 (China)]. E-mail: bmli@fudan.edu.cn

    2006-02-24T23:59:59.000Z

    Tob (transducer of ErbB-2) is a negative cell cycle regulator with anti-proliferative activity in peripheral tissues. Our previous study identified Tob as a protein involved in hippocampus-dependent memory consolidation (M.L. Jin, X.M. Wang, Y.Y. Tu, X.H. Zhang, X. Gao, N. Guo, Z.Q. Xie, G.P. Zhao, N.H. Jing, B.M. Li, Y.Yu, The negative cell cycle regulator, Tob (Transducer of ErbB-2), is a multifunctional protein involved in hippocampus-dependent learning and memory, Neuroscience 131 (2005) 647-659). Here, we provide evidence that Tob in the central nervous system is engaged in acquisition of motor skill. Tob has a relatively high expression in the cerebellum. Tob expression is up-regulated in the cerebellum after rats receive training on a rotarod-running task. Rats infused with Tob antisense oligonucleotides into the 4th ventricle exhibit a severe deficit in running on a rotating rod or walking across a horizontally elevated beam.

  1. The Crystal Structure and Mechanism of an Unusual Oxidoreductase, GilR, Involved in Gilvocarcin V Biosynthesis

    SciTech Connect (OSTI)

    Noinaj, Nicholas; Bosserman, Mary A.; Schickli, M. Alexandra; Piszczek, Grzegorz; Kharel, Madan K.; Pahari, Pallab; Buchanan, Susan K.; Rohr, Jürgen (NIH); (Kentucky)

    2012-11-26T23:59:59.000Z

    GilR is a recently identified oxidoreductase that catalyzes the terminal step of gilvocarcin V biosynthesis and is a unique enzyme that establishes the lactone core of the polyketide-derived gilvocarcin chromophore. Gilvocarcin-type compounds form a small distinct family of anticancer agents that are involved in both photo-activated DNA-alkylation and histone H3 cross-linking. High resolution crystal structures of apoGilR and GilR in complex with its substrate pregilvocarcin V reveals that GilR belongs to the small group of a relatively new type of the vanillyl-alcohol oxidase flavoprotein family characterized by bicovalently tethered cofactors. GilR was found as a dimer, with the bicovalently attached FAD cofactor mediated through His-65 and Cys-125. Subsequent mutagenesis and functional assays indicate that Tyr-445 may be involved in reaction catalysis and in mediating the covalent attachment of FAD, whereas Tyr-448 serves as an essential residue initiating the catalysis by swinging away from the active site to accommodate binding of the 6R-configured substrate and consequently abstracting the proton of the hydroxyl residue of the substrate hemiacetal 6-OH group. These studies lay the groundwork for future enzyme engineering to broaden the substrate specificity of this bottleneck enzyme of the gilvocarcin biosynthetic pathway for the development of novel anti-cancer therapeutics.

  2. ISDAC Modeling

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville PowerCherries 82981-1cnHigh School footballHydrogen andHypernucleiNORTHWESTOfficeModeling Modeling

  3. MODELING HUMAN RELIABILITY ANALYSIS USING MIDAS

    SciTech Connect (OSTI)

    Ronald L. Boring; Donald D. Dudenhoeffer; Bruce P. Hallbert; Brian F. Gore

    2006-05-01T23:59:59.000Z

    This paper summarizes an emerging collaboration between Idaho National Laboratory and NASA Ames Research Center regarding the utilization of high-fidelity MIDAS simulations for modeling control room crew performance at nuclear power plants. The key envisioned uses for MIDAS-based control room simulations are: (i) the estimation of human error with novel control room equipment and configurations, (ii) the investigative determination of risk significance in recreating past event scenarios involving control room operating crews, and (iii) the certification of novel staffing levels in control rooms. It is proposed that MIDAS serves as a key component for the effective modeling of risk in next generation control rooms.

  4. Computational fire modeling for aircraft fire research

    SciTech Connect (OSTI)

    Nicolette, V.F.

    1996-11-01T23:59:59.000Z

    This report summarizes work performed by Sandia National Laboratories for the Federal Aviation Administration. The technical issues involved in fire modeling for aircraft fire research are identified, as well as computational fire tools for addressing those issues, and the research which is needed to advance those tools in order to address long-range needs. Fire field models are briefly reviewed, and the VULCAN model is selected for further evaluation. Calculations are performed with VULCAN to demonstrate its applicability to aircraft fire problems, and also to gain insight into the complex problem of fires involving aircraft. Simulations are conducted to investigate the influence of fire on an aircraft in a cross-wind. The interaction of the fuselage, wind, fire, and ground plane is investigated. Calculations are also performed utilizing a large eddy simulation (LES) capability to describe the large- scale turbulence instead of the more common k-{epsilon} turbulence model. Additional simulations are performed to investigate the static pressure and velocity distributions around a fuselage in a cross-wind, with and without fire. The results of these simulations provide qualitative insight into the complex interaction of a fuselage, fire, wind, and ground plane. Reasonable quantitative agreement is obtained in the few cases for which data or other modeling results exist Finally, VULCAN is used to quantify the impact of simplifying assumptions inherent in a risk assessment compatible fire model developed for open pool fire environments. The assumptions are seen to be of minor importance for the particular problem analyzed. This work demonstrates the utility of using a fire field model for assessing the limitations of simplified fire models. In conclusion, the application of computational fire modeling tools herein provides both qualitative and quantitative insights into the complex problem of aircraft in fires.

  5. Modelling osteomyelitis

    E-Print Network [OSTI]

    Liò, Pietro; Paoletti, Nicola; Moni, Mohammad A; Atwell, Kathryn; Merelli, Emanuela; Viceconti, Marco

    2012-09-07T23:59:59.000Z

    13 of 14 12. Paoletti N, Lio P, Merelli E, Viceconti M: Multi-level Computational Modeling and Quantitative Analysis of Bone Remodeling. IEEE/ACM Transactions on Computational Biology and Bioinformatics 2012, 99(PrePrints). 13. Geris L, Vander Sloten...

  6. Criticality Model

    SciTech Connect (OSTI)

    A. Alsaed

    2004-09-14T23:59:59.000Z

    The ''Disposal Criticality Analysis Methodology Topical Report'' (YMP 2003) presents the methodology for evaluating potential criticality situations in the monitored geologic repository. As stated in the referenced Topical Report, the detailed methodology for performing the disposal criticality analyses will be documented in model reports. Many of the models developed in support of the Topical Report differ from the definition of models as given in the Office of Civilian Radioactive Waste Management procedure AP-SIII.10Q, ''Models'', in that they are procedural, rather than mathematical. These model reports document the detailed methodology necessary to implement the approach presented in the Disposal Criticality Analysis Methodology Topical Report and provide calculations utilizing the methodology. Thus, the governing procedure for this type of report is AP-3.12Q, ''Design Calculations and Analyses''. The ''Criticality Model'' is of this latter type, providing a process evaluating the criticality potential of in-package and external configurations. The purpose of this analysis is to layout the process for calculating the criticality potential for various in-package and external configurations and to calculate lower-bound tolerance limit (LBTL) values and determine range of applicability (ROA) parameters. The LBTL calculations and the ROA determinations are performed using selected benchmark experiments that are applicable to various waste forms and various in-package and external configurations. The waste forms considered in this calculation are pressurized water reactor (PWR), boiling water reactor (BWR), Fast Flux Test Facility (FFTF), Training Research Isotope General Atomic (TRIGA), Enrico Fermi, Shippingport pressurized water reactor, Shippingport light water breeder reactor (LWBR), N-Reactor, Melt and Dilute, and Fort Saint Vrain Reactor spent nuclear fuel (SNF). The scope of this analysis is to document the criticality computational method. The criticality computational method will be used for evaluating the criticality potential of configurations of fissionable materials (in-package and external to the waste package) within the repository at Yucca Mountain, Nevada for all waste packages/waste forms. The criticality computational method is also applicable to preclosure configurations. The criticality computational method is a component of the methodology presented in ''Disposal Criticality Analysis Methodology Topical Report'' (YMP 2003). How the criticality computational method fits in the overall disposal criticality analysis methodology is illustrated in Figure 1 (YMP 2003, Figure 3). This calculation will not provide direct input to the total system performance assessment for license application. It is to be used as necessary to determine the criticality potential of configuration classes as determined by the configuration probability analysis of the configuration generator model (BSC 2003a).

  7. Sandia National Laboratories: Modeling

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Mark Boslough Featured in NOVA Special about the Chelyabinsk Meteor On April 3, 2013, in Capabilities, Computational Modeling & Simulation, Modeling, Modeling, Modeling & Analysis,...

  8. Exploring the Genome and Proteome of Desulfitobacterium hafniense DCB2 for its Protein Complexes Involved in Metal Reduction and Dechlorination

    SciTech Connect (OSTI)

    Kim, Sang-Hoon, Christina Harzman, John K. Davis, Rachel Hutcheson, Joan B. Broderick, Terence L. Marsh, James M. Tiedje.

    2012-09-27T23:59:59.000Z

    Desulfitobacteria are of interest to DOE mission because of their ability to reduce many electron acceptors including Fe(III), U(VI), Cr(VI), As(V), Mn(IV), Se(VI), NO3- and well as CO2, sulfite, fumarate and humates, their ability to colonize more stressful environments because they form spores, fix nitrogen and they have the more protective Gram positive cell walls. Furthermore at least some of them reductively dechlorinate aromatic and aliphatic pollutants. Importantly, most of the metals and the organochlorine reductions are coupled to ATP production and support growth providing for the organism's natural selection at DOE's contaminant sites. This work was undertaken to gain insight into the genetic and metabolic pathways involved in dissimilatory metal reduction and reductive dechlorination, (ii) to discern the commonalities among these electron-accepting processes, (iii) to identify multi-protein complexes catalyzing these functions and (iv) to elucidate the coordination in expression of these pathways and processes.

  9. DNA rearrangement in human follicular lymphoma can involve the 5' or the 3' region of the bcl-2 gene

    SciTech Connect (OSTI)

    Tsujimoto, Y.; Bashir, M.M.; Givol, I.; Cossman, J.; Jaffe, E.; Croce, C.M.

    1987-03-01T23:59:59.000Z

    In most human lymphomas, the chromosome translocation t(14;18) occurs within two breakpoint clustering regions on chromosome 18, the major one at the 3' untranslated region of the bcl-2 gene and the minor one at 3' of the gene. Analysis of a panel of follicular lymphoma DNAs using probes for the first exon of the bcl-2 gene indicates that DNA rearrangements may also occur 5' to the involved bcl-2 gene. In this case the IgH locus and the bcl-2 gene are found in an order suggesting that an inversion also occurred during the translocation process. The coding region of the bcl-2 gene, however, are left intact in all cases of follicular lymphoma studied to date.

  10. DOE Technical Standards List. Directory of DOE and contractor personnel involved in non-government standards activities

    SciTech Connect (OSTI)

    NONE

    1997-06-01T23:59:59.000Z

    This is a periodic report on the level of agency participation in non-Government standards activities. This technical standards list is intended to assist US Department of Energy (DOE) management and other personnel involved in the DOE technical Standards Program by identifying those participating individuals. The body of this document contains a listing of DOE employees and DOE contractors who have submitted a Record of Non-Government Standards Activity. Additional names were added from rosters supplied by non-Government standards bodies. Appendices to this document are provided to list the information by parent employment organization, by non-Government standards activity, and by the proper names of the non-Government standards organizations and committees.

  11. Structural characterization of a family of cytochromes c{sub 7} involved in Fe(III) respiration by Geobacter sulfurreducens.

    SciTech Connect (OSTI)

    Pokkuluri, P. R.; Londer, Y. Y.; Yang, X.; Duke, N. E. C.; Erickson, J.; Orshonsky, V.; Johnson, G.; Schiffer, M.; Biosciences Division

    2010-02-01T23:59:59.000Z

    Periplasmic cytochromes c{sub 7} are important in electron transfer pathway(s) in Fe(III) respiration by Geobacter sulfurreducens. The genome of G. sulfurreducens encodes a family of five 10-kDa, three-heme cytochromes c{sub 7}. The sequence identity between the five proteins (designated PpcA, PpcB, PpcC, PpcD, and PpcE) varies between 45% and 77%. Here, we report the high-resolution structures of PpcC, PpcD, and PpcE determined by X-ray diffraction. This new information made it possible to compare the sequences and structures of the entire family. The triheme cores are largely conserved but are not identical. We observed changes, due to different crystal packing, in the relative positions of the hemes between two molecules in the crystal. The overall protein fold of the cytochromes is similar. The structure of PpcD differs most from that of the other homologs, which is not obvious from the sequence comparisons of the family. Interestingly, PpcD is the only cytochrome c{sub 7} within the family that has higher abundance when G. sulfurreducens is grown on insoluble Fe(III) oxide compared to ferric citrate. The structures have the highest degree of conservation around 'heme IV'; the protein surface around this heme is positively charged in all of the proteins, and therefore all cytochromes c{sub 7} could interact with similar molecules involving this region. The structures and surface characteristics of the proteins near the other two hemes, 'heme I' and 'heme III', differ within the family. The above observations suggest that each of the five cytochromes c{sub 7} could interact with its own redox partner via an interface involving the regions of heme I and/or heme III; this provides a possible rationalization for the existence of five similar proteins in G. sulfurreducens.

  12. Comprehensive computer model for magnetron sputtering. II. Charged particle transport

    SciTech Connect (OSTI)

    Jimenez, Francisco J., E-mail: fjimenez@ualberta.ca; Dew, Steven K. [Department of Electrical and Computer Engineering, University of Alberta, Edmonton T6G 2V4 (Canada); Field, David J. [Smith and Nephew (Alberta) Inc., Fort Saskatchewan T8L 4K4 (Canada)

    2014-11-01T23:59:59.000Z

    Discharges for magnetron sputter thin film deposition systems involve complex plasmas that are sensitively dependent on magnetic field configuration and strength, working gas species and pressure, chamber geometry, and discharge power. The authors present a numerical formulation for the general solution of these plasmas as a component of a comprehensive simulation capability for planar magnetron sputtering. This is an extensible, fully three-dimensional model supporting realistic magnetic fields and is self-consistently solvable on a desktop computer. The plasma model features a hybrid approach involving a Monte Carlo treatment of energetic electrons and ions, along with a coupled fluid model for thermalized particles. Validation against a well-known one-dimensional system is presented. Various strategies for improving numerical stability are investigated as is the sensitivity of the solution to various model and process parameters. In particular, the effect of magnetic field, argon gas pressure, and discharge power are studied.

  13. SECURITY MODELING FOR MARITIME PORT DEFENSE RESOURCE ALLOCATION

    SciTech Connect (OSTI)

    Harris, S.; Dunn, D.

    2010-09-07T23:59:59.000Z

    Redeployment of existing law enforcement resources and optimal use of geographic terrain are examined for countering the threat of a maritime based small-vessel radiological or nuclear attack. The evaluation was based on modeling conducted by the Savannah River National Laboratory that involved the development of options for defensive resource allocation that can reduce the risk of a maritime based radiological or nuclear threat. A diverse range of potential attack scenarios has been assessed. As a result of identifying vulnerable pathways, effective countermeasures can be deployed using current resources. The modeling involved the use of the Automated Vulnerability Evaluation for Risks of Terrorism (AVERT{reg_sign}) software to conduct computer based simulation modeling. The models provided estimates for the probability of encountering an adversary based on allocated resources including response boats, patrol boats and helicopters over various environmental conditions including day, night, rough seas and various traffic flow rates.

  14. Methodology for Modeling Building Energy Performance across the Commercial Sector

    SciTech Connect (OSTI)

    Griffith, B.; Long, N.; Torcellini, P.; Judkoff, R.; Crawley, D.; Ryan, J.

    2008-03-01T23:59:59.000Z

    This report uses EnergyPlus simulations of each building in the 2003 Commercial Buildings Energy Consumption Survey (CBECS) to document and demonstrate bottom-up methods of modeling the entire U.S. commercial buildings sector (EIA 2006). The ability to use a whole-building simulation tool to model the entire sector is of interest because the energy models enable us to answer subsequent 'what-if' questions that involve technologies and practices related to energy. This report documents how the whole-building models were generated from the building characteristics in 2003 CBECS and compares the simulation results to the survey data for energy use.

  15. Comparative evaluation of network flow programming and conventional reservoir system simulation models

    E-Print Network [OSTI]

    Yerramreddy, Anilkumar

    1993-01-01T23:59:59.000Z

    ANALYSIS MODELS Operating river/reservoir systems in an optimal manner is an important and com- plex area of water resources planning and management. Reservoir system operation involves: allocating storage capacity and water resources between multiple... broad array of analysis capabilities, have been developed over the past several decades to support planning studies and management decisions. Reservoir system analysis models can be categorized as (I) simulation models, (2) optimization models...

  16. Arguments towards the construction of a matrix model groundstate

    E-Print Network [OSTI]

    Boulton, L; Restuccia, A

    2015-01-01T23:59:59.000Z

    We discuss the existence and uniqueness of wavefunctions for inhomogenoeus boundary value problems associated to x^2y^2-type matrix model on a bounded domain of R^2. Both properties involve a combination of the Cauchy-Kovalewski Theorem and a explicit calculations.

  17. Model-Based Dependability Analysis of Programmable Drug Infusion Pumps

    E-Print Network [OSTI]

    Sankaranarayanan, Sriram

    Model-Based Dependability Analysis of Programmable Drug Infusion Pumps Sriram Sankaranarayanan.lastname@colorado.edu Abstract. Infusion pumps are commonly used in home/hospital care to inject drugs into a patient a case-study involving an infusion pump used to manage pain through the infusion of analgesic drugs

  18. Using Active Deformable Models in Robotic Visual Servoing

    E-Print Network [OSTI]

    of Minnesota 4-192 EE/CS Building 200 Union Street SE Minneapolis, MN 55455 September 9, 1997 Submitted to the book \\Event-Based Sensing, Planning and Control of a Robotic System: An Integrated Approach" #12 are updated at frame rates by minimizing an energy function involving the relative position of model points

  19. Mathematical Modeling of Blood Clotting: The Interplay of Coagulation Chemistry,

    E-Print Network [OSTI]

    Ciocan-Fontanine, Ionut

    Mathematical Modeling of Blood Clotting: The Interplay of Coagulation Chemistry, Platelet of a blood clot inside of a blood vessel, a process known as thrombosis, involves the intertwined processes, of aggregated platelets, fibrin polymer mesh, and trapped red and white blood cells. Thrombosis can be initiated

  20. Revised NIH Model M-CRADA Monday, October 22, 2007

    E-Print Network [OSTI]

    Baker, Chris I.

    Revised NIH Model M-CRADA Monday, October 22, 2007 Page 1 of 10 NATIONAL INSTITUTES OF HEALTH Agreement ("M-CRADA") has been adopted for use by the Institutes and Centers of the National Institutes are collected in Appendix B. Appendices A and B are incorporated herein by reference. This M-CRADA involves

  1. Duhem Models for Hysteresis in Sliding and Presliding Friction* JinHyoung Oh, Ashwani K. Padthe, Dennis S. Bernstein, Demosthenis D. Rizos, and Spilios D. Fassois

    E-Print Network [OSTI]

    Sontag, Eduardo

    , namely, Coulomb friction, is discontinuous. Discontinuous dry friction models are studied in [15]. Some is challenging since some models involve nonsmooth dynamics. For example, the most widely used dry friction modelDuhem Models for Hysteresis in Sliding and Presliding Friction* JinHyoung Oh, Ashwani K. Padthe

  2. Modification and Validation of a Universal Thermodynamic Chiller Model Used to Evaluate the Performance of Water-Cooled Centrifugal Chillers

    E-Print Network [OSTI]

    Figueroa, I. E.; Cathey, M.; Medina, M. A.; Nutter, D. W.

    1998-01-01T23:59:59.000Z

    This paper presents modifications made to the procedure used to develop a universal thermodynamic model of chillers (Gordon and Ng, 1995). The modifications were necessary to capture physical phenomena involved when water is the coolant fluid...

  3. ccsd-00085042,version1-11Jul2006 A Two-dimensional eddy current model using thin

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    ccsd-00085042,version1-11Jul2006 A Two-dimensional eddy current model using thin inductors Youcef a mathematical model for eddy currents in two dimensional geometries where the conductors are thin domains. We Mathematical modelling of eddy current problems often involves multiple conductors with various sizes

  4. Modelling of Gas Clathrate Hydrate Equilibria using the Electrolyte Non-Random Two-Liquid (eNRTL) Model

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    1 Modelling of Gas Clathrate Hydrate Equilibria using the Electrolyte Non-Random Two-Liquid (e + salt2 + gas} systems (salt = NaCl, KCl, CaCl2; gas = CH4, CO2) comprising a gas clathrate hydrate phase-electrolyte aqueous systems involving gas hydrate phases. In the H-Lw-G calculations, fugacities in the gas phase were

  5. Accurate Computer Simulation of Phase Equilibrium for Complex Fluid Mixtures. Application to Binaries Involving Isobutene, Methanol, Methyl tert-Butyl Ether, and

    E-Print Network [OSTI]

    Lisal, Martin

    to Binaries Involving Isobutene, Methanol, Methyl tert-Butyl Ether, and n-Butane Martin Li´sal,*,, William R + methyl tert-butyl ether (MTBE) and the binaries formed by methanol with isobutene, MTBE, and n

  6. DOE Partnerships with States, Tribes and Other Federal Programs Help Responders Prepare for Challenges Involving Transport of Radioactive Materials

    SciTech Connect (OSTI)

    Marsha Keister

    2001-02-01T23:59:59.000Z

    DOE Partnerships with States, Tribes and Other Federal Programs Help Responders Prepare for Challenges Involving Transport of Radioactive Materials Implementing adequate institutional programs and validating preparedness for emergency response to radiological transportation incidents along or near U.S. Department of Energy (DOE) shipping corridors poses unique challenges to transportation operations management. Delayed or insufficient attention to State and Tribal preparedness needs may significantly impact the transportation operations schedule and budget. The DOE Transportation Emergency Preparedness Program (TEPP) has successfully used a cooperative planning process to develop strong partnerships with States, Tribes, Federal agencies and other national programs to support responder preparedness across the United States. DOE TEPP has found that building solid partnerships with key emergency response agencies ensures responders have access to the planning, training, technical expertise and assistance necessary to safely, efficiently and effectively respond to a radiological transportation accident. Through the efforts of TEPP over the past fifteen years, partnerships have resulted in States and Tribal Nations either using significant portions of the TEPP planning resources in their programs and/or adopting the Modular Emergency Response Radiological Transportation Training (MERRTT) program into their hazardous material training curriculums to prepare their fire departments, law enforcement, hazardous materials response teams, emergency management officials, public information officers and emergency medical technicians for responding to transportation incidents involving radioactive materials. In addition, through strong partnerships with Federal Agencies and other national programs TEPP provided technical expertise to support a variety of radiological response initiatives and assisted several programs with integration of the nationally recognized MERRTT program into other training venues, thus ensuring consistency of radiological response curriculums delivered to responders. This presentation will provide an overview of the steps to achieve coordination, to avoid redundancy, and to highlight several of the successful partnerships TEPP has formed with States, Tribes, Federal agencies and other national programs. Events, accident scenarios, and training where TEPP was proven to be integral in building the radiological response capabilities for first responders to actual radiological incidents are also highlighted. Participants will gain an appreciation for the collaborative efforts States and Tribes are engaging in with the DOE to ensure that responders all along the DOE transportation corridors are adequately prepared to respond to shipments of radioactive materials through their communities.

  7. Projecting Fatalities in Crashes Involving Older Drivers, 2000–2025, CRADA No. ORNL98-0500 Final Report

    SciTech Connect (OSTI)

    Hu, Patricia S. [ORNL] [ORNL; Jones, Donald W. [ORNL] [ORNL; Reuscher, Timothy [Oak Ridge Institute for Science and Education] [Oak Ridge Institute for Science and Education; Schmoyer, Richard S. [ORNL] [ORNL; Truett, Lorena F. [ORNL] [ORNL

    2000-04-01T23:59:59.000Z

    At the turn of the century – the 20th century that is – the median age in the United States was under 30 years; America was 60% rural in nature; and there were only 36 highway fatalities all year. As we leave the 20th century behind, the route into the 21st century is very different. “Intelligent” cars speed down multi-lane “smart” highways in a nation that is 75% urban. According to the Federal Highway Administration’s Highway Statistics, there are 28,000 times more vehicles on the road in 2000 than there were in 1900, and these vehicles travel about 2.6 trillion miles each year. Annual fatalities resulting from highway crashes have also increased – by over 1100%. We see other changes as well. The face of America is changing. It is growing older. In 2025, persons 65 and over will make up 18.5% of the total population. The number of persons aged 85 and over is increasing more rapidly than any other age group. More importantly, the elderly are taking more trips, driving further, and continuing to drive much later in life. These conditions lead to concerns about traffic safety. Although the elderly are healthier and drive safer cars than they did just two decades ago, their frailty makes them more susceptible to injury than younger persons involved in traffic crashes of the same severity. In addition, visual, physical, and cognitive skills, all of which contribute to driving abilities, decrease with advancing age. The familiar “U”-shaped curve depicting the rate of fatalities per vehicle miles traveled, shows that the elderly experience a higher highway fatality rate than any other age group except teenagers. While the overall number of highway fatalities has decreased regularly since 1972, the number of fatalities of elderly travelers has continued to increase steadily. This increase is cause for concern for both the elderly driver and for other persons on the roads who migh tbe placed in danger through crashes involving elderly drivers.

  8. Interfaces and Free Boundaries 11 (2009), 239258 Two-phase flows involving capillary barriers in heterogeneous porous media

    E-Print Network [OSTI]

    Porretta, Alessio

    2009-01-01T23:59:59.000Z

    and immiscible oil-water flow through , and thus through each i. By Darcy's law, the conservation of oil medium leads to the phenomena of oil-trapping and oil-expulsion, which is modelled with discontinuous and water phases is given for all (x, t) i ×]0, T [ by the equations it ui(x, t) - · o,i(ui(x, t))( po

  9. Translating Model Simulators to Analysis Models

    E-Print Network [OSTI]

    de Lara, Juan

    Translating Model Simulators to Analysis Models Juan de Lara1 and Hans Vangheluwe2 1 Polytechnic generation of model-to-model transformations given a description of the operational semantics of the source of operational triple graph grammar rules that transform the static information (initial model) and the dynamics

  10. Graphical models, causal inference, and econometric models

    E-Print Network [OSTI]

    Spirtes, Peter

    Graphical models, causal inference, and econometric models Peter Spirtes Abstract A graphical model modeling has historical ties to causal modeling in econometrics and other social sciences, there have been isolated from the econometric tradition. In this paper I will describe a number of recent developments

  11. A Simulation and Modeling Framework for Space Situational Awareness

    SciTech Connect (OSTI)

    Olivier, S S

    2008-09-15T23:59:59.000Z

    This paper describes the development and initial demonstration of a new, integrated modeling and simulation framework, encompassing the space situational awareness enterprise, for quantitatively assessing the benefit of specific sensor systems, technologies and data analysis techniques. The framework is based on a flexible, scalable architecture to enable efficient, physics-based simulation of the current SSA enterprise, and to accommodate future advancements in SSA systems. In particular, the code is designed to take advantage of massively parallel computer systems available, for example, at Lawrence Livermore National Laboratory. The details of the modeling and simulation framework are described, including hydrodynamic models of satellite intercept and debris generation, orbital propagation algorithms, radar cross section calculations, optical brightness calculations, generic radar system models, generic optical system models, specific Space Surveillance Network models, object detection algorithms, orbit determination algorithms, and visualization tools. The use of this integrated simulation and modeling framework on a specific scenario involving space debris is demonstrated.

  12. Visible light stimulating dual-wavelength emission and O vacancy involved energy transfer behavior in luminescence for coaxial nanocable arrays

    SciTech Connect (OSTI)

    Yang, Lei, E-mail: nanoyang@qq.com [College of Materials Science and Engineering, Hunan University, Changsha 410082 (China); Hunan Province Key Laboratory for Spray Deposition Technology and Application, Hunan University, Changsha 410082 (China); Dong, Jiazhang; Jiang, Zhongcheng [College of Materials Science and Engineering, Hunan University, Changsha 410082 (China); Pan, Anlian; Zhuang, Xiujuan [Key Laboratory for Micro-Nano Physics and Technology of Hunan Province, Hunan University, Changsha 410082 (China)

    2014-06-14T23:59:59.000Z

    We report a strategy to investigate O vacancy (V{sub O}) involved energy transfer and dual-wavelength yellow emission in coaxial nanocable. By electric field deposition and subsequent sol-gel template approach, ZnO:Tb/Y{sub 2}O{sub 3}:Eu coaxial nanocable arrays are synthesized. After visible light excitation, system is promoted to O vacancy charge transfer state of V{sub O}(0/+). In the following cross relaxation, energy transfer from V{sub O} to the excitation energy level of Tb{sup 3+} in ZnO:Tb core area. While in Y{sub 2}O{sub 3}:Eu shell area, energy transfer to the excitation energy level of Eu{sup 3+}. Subsequently, dual-wavelength emission is observed. By constructing nanocable with dual-wavelength emission, yellow luminescence is obtained. Adjust doping concentration of Eu{sup 3+} or Tb{sup 3+} in the range of 0.01–0.05, chromaticity coordinates of ZnO:Tb/Y{sub 2}O{sub 3}:Eu nanocable stably stays at yellow region in color space except ZnO:Tb{sub 0.01}/Y{sub 2}O{sub 3}:Eu{sub 0.01}. As Vo states act as media in energy transfer process in nanocablers, visible light can stimulate dual-wavelength emissions. Yellow luminescent nanocable arrays will have great applications in light-emitting diode luminescence.

  13. Nuclear substructure reorganization during late stageerythropoiesis is selective and does not involve caspase cleavage ofmajor nuclear substructural proteins

    SciTech Connect (OSTI)

    Krauss, Sharon Wald; Lo, Annie J.; Short, Sarah A.; Koury, MarkJ.; Mohandas, Narla; Chasis, Joel Anne

    2005-04-06T23:59:59.000Z

    Enucleation, a rare feature of mammalian differentiation, occurs in three cell types: erythroblasts, lens epithelium and keratinocytes. Previous investigations suggest that caspase activation functions in lens epithelial and keratinocyte enucleation, as well as in early erythropoiesis encompassing BFU-E differentiation to proerythroblast. To determine whether caspase activation contributes to later erythropoiesis and whether nuclear substructures other than chromatin reorganize, we analyzed distributions of nuclear subcompartment proteins and assayed for caspase-induced cleavage of subcompartmental target proteins in mouse erythroblasts. We found that patterns of lamin B in the filamentous network interacting with both the nuclear envelope and DNA, nuclear matrix protein NuMA, and splicing factors Sm and SC35 persisted during nuclear condensation, consistent with effective transcription of genes expressed late in differentiation. Thus nuclear reorganization prior to enucleation is selective, allowing maintenance of critical transcriptional processes independent of extensive chromosomal reorganization. Consistent with these data, we found no evidence for caspase-induced cleavage of major nuclear subcompartment proteins during late erythropoiesis, in contrast to what has been observed in early erythropoiesis and in lens epithelial and keratinocyte differentiation. These findings imply that nuclear condensation and extrusion during terminal erythroid differentiation involve novel mechanisms that do not entail major activation of apoptotic machinery.

  14. G-protein-coupled estrogen receptor 1 is involved in brain development during zebrafish (Danio rerio) embryogenesis

    SciTech Connect (OSTI)

    Shi, Yanan; Liu, Xiaochun [State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals and Guangdong Provincial Key Laboratory for Aquatic Economic Animals, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275 (China)] [State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals and Guangdong Provincial Key Laboratory for Aquatic Economic Animals, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275 (China); Zhu, Pei; Li, Jianzhen; Sham, Kathy W.Y. [School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong (China)] [School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong (China); Cheng, Shuk Han [Department of Biology and Chemistry, City University of Hong Kong, Kowloon, Hong Kong (China)] [Department of Biology and Chemistry, City University of Hong Kong, Kowloon, Hong Kong (China); Li, Shuisheng; Zhang, Yong [State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals and Guangdong Provincial Key Laboratory for Aquatic Economic Animals, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275 (China)] [State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals and Guangdong Provincial Key Laboratory for Aquatic Economic Animals, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275 (China); Cheng, Christopher H.K., E-mail: chkcheng@cuhk.edu.hk [School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong (China); Lin, Haoran, E-mail: lsslhr@mail.sysu.edu.cn [State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals and Guangdong Provincial Key Laboratory for Aquatic Economic Animals, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275 (China) [State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals and Guangdong Provincial Key Laboratory for Aquatic Economic Animals, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275 (China); College of Ocean, Hainan University, Haikou 570228, Hainan (China)

    2013-05-24T23:59:59.000Z

    Highlights: •The Gper expression was detected in the developing brain of zebrafish. •Gper morpholino knockdown induced apoptosis of brain cells. •Gper morpholino knockdown reduced expression in neuron markers. •Zebrafish Gper may be involved in neuronal development. -- Abstract: G-protein-coupled estrogen receptor 1 (Gper, formerly known as GPR30) is found to be a trophic and protective factor in mediating action of estrogen in adult brain, while its role in developing brain remains to be elucidated. Here we present the expression pattern of Gper and its functions during embryogenesis in zebrafish. Both the mRNA and protein of Gper were detected throughout embryogenesis. Whole mount in situ hybridization (WISH) revealed a wide distribution of gper mRNAs in various regions of the developing brain. Gper knockdown by specific morpholinos resulted in growth retardation in embryos and morphological defects in the developing brain. In addition, induced apoptosis, decreased proliferation of the brain cells and maldevelopment of sensory and motor neurons were also found in the morphants. Our results provide novel insights into Gper functions in the developing brain, revealing that Gper can maintain the survival of the brain cells, and formation and/or differentiation of the sensory and motor neurons.

  15. A cytoskeleton-associated protein, TMAP/CKAP2, is involved in the proliferation of human foreskin fibroblasts

    SciTech Connect (OSTI)

    Jeon, Sang-Min [Department of Molecular Cell Biology and Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Suwon (Korea, Republic of); Choi, Bongkun [Department of Molecular Cell Biology and Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Suwon (Korea, Republic of); Hong, Kyung Uk [Department of Molecular Cell Biology and Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Suwon (Korea, Republic of); Kim, Eunhee [Department of Molecular Cell Biology and Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Suwon (Korea, Republic of); Seong, Yeon-Sun [Department of Biochemistry, Dankook University College of Medicine, Chunan (Korea, Republic of); Bae, Chang-Dae [Department of Molecular Cell Biology and Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Suwon (Korea, Republic of); Park, Joobae [Department of Molecular Cell Biology and Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Suwon (Korea, Republic of)]. E-mail: jbpark@med.skku.ac.kr

    2006-09-15T23:59:59.000Z

    Previously, we reported the cloning of a cytoskeleton-associated protein, TMAP/CKAP2, which was up-regulated in primary human gastric cancers. Although TMAP/CKAP2 has been found to be expressed in most cancer cell lines examined, the function of CKAP2 is not known. In this study, we found that TMAP/CKAP2 was not expressed in G0/G1 arrested HFFs, but that it was expressed in actively dividing cells. After initiating the cell cycle, TMAP/CKAP2 levels remained low throughout most of the G1 phase, but gradually increased between late G1 and G2/M. Knockdown of TMAP/CKAP2 reduced pRB phosphorylation and increased p27 expression, and consequently reduced HFF proliferation, whereas constitutive TMAP/CKAP2 expression increased pRB phosphorylation and enhanced proliferation. Our results show that this novel cytoskeleton-associated protein is expressed cell cycle dependently and that it is involved in cell proliferation.

  16. Conformation Changes N-terminal Involvement and cGMP Signal Relay in the Phosphodiesterase-5 GAF Domain

    SciTech Connect (OSTI)

    H Wang; H Robinson; H Ke

    2011-12-31T23:59:59.000Z

    The activity of phosphodiesterase-5 (PDE5) is specific for cGMP and is regulated by cGMP binding to GAF-A in its regulatory domain. To better understand the regulatory mechanism, x-ray crystallographic and biochemical studies were performed on constructs of human PDE5A1 containing the N-terminal phosphorylation segment, GAF-A, and GAF-B. Superposition of this unliganded GAF-A with the previously reported NMR structure of cGMP-bound PDE5 revealed dramatic conformational differences and suggested that helix H4 and strand B3 probably serve as two lids to gate the cGMP-binding pocket in GAF-A. The structure also identified an interfacial region among GAF-A, GAF-B, and the N-terminal loop, which may serve as a relay of the cGMP signal from GAF-A to GAF-B. N-terminal loop 98-147 was physically associated with GAF-B domains of the dimer. Biochemical analyses showed an inhibitory effect of this loop on cGMP binding and its involvement in the cGMP-induced conformation changes.

  17. Molecular cloning and sequence of the thdF gene involved in the thiophene and furan oxidation by Escherichia coli

    SciTech Connect (OSTI)

    Alam, K.Y.; Clark, D.P.

    1990-01-01T23:59:59.000Z

    Since sulfur dioxide emission from burning high sulfur coals is a major contributor to acid rain, it is important to develop bacteria which are capable of efficiently removing the sulfur from coal before combustion. Inorganic sulfur can be removed from coal by certain strains of Thiobacillus or Sulfolobus; however the organic sulfur remains intransigent. Since high sulfur Illinois coals typically contain 60% to 70% of their sulfur in the form of the heterocyclic thiophene ring we have started to investigate the biodegradation of derivatives of thiophene and the corresponding oxygen heterocycle, furan. Our previous work resulted in the isolation of a triple mutant, NAR30, capable of oxidizing a range of furan and thiophene derivatives. However, NAR30 does not completely degrade thiophenes or furans and its oxidation of these compounds is slow and inefficient. We decided to clone the thd genes both in order to increase the efficiency of degradation and to investigate the nature of the reactions involved. 37 refs., 4 figs., 3 tabs.

  18. A framework for modeling the consequences of the propagation of automation degradation: application to

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    A framework for modeling the consequences of the propagation of automation degradation: application of automation degradation in the context of a socio-technical network. This modelling approach involves two integrating these two views for describing the evolution of system performances under automation degradation

  19. CALTECH ASCI TECHNICAL REPORT 165 Reconstruction of subgrid models for nonpremixed combustion

    E-Print Network [OSTI]

    CALTECH ASCI TECHNICAL REPORT 165 Reconstruction of subgrid models for nonpremixed combustion J. P. Medallo, S. Sarkar and C. Pantano #12;Reconstruction subgrid models for nonpremixed combustion J. P 2003; published 16 September 2003 Large-eddy simulation of combustion problems involves highly

  20. A comparative study of continuous-time modelings for scheduling of crude oil operations

    E-Print Network [OSTI]

    Grossmann, Ignacio E.

    on its efficient performance for industrial problems. Keywords: Crude oil scheduling; event-based model problem is the first and critical stage of the crude oil refining process. The problem involves crude oilA comparative study of continuous-time modelings for scheduling of crude oil operations Xuan Chena

  1. Models of Sequential Learning Paul J. Reber, Daniel J. Sanchez, Eric W. Gobel

    E-Print Network [OSTI]

    Stehr, Mark-Oliver

    with this type of learning, suggesting that a common computational mechanism in this region may be involved in many types of syntax. Computational models that do statistical learning can be based on simple BayesianModels of Sequential Learning Paul J. Reber, Daniel J. Sanchez, Eric W. Gobel Department

  2. THE MULTILINEAR ICA DECOMPOSITION WITH APPLICATIONS TO NSS MODELING Raghu G. Raj and Alan C. Bovik

    E-Print Network [OSTI]

    Texas at Austin, University of

    ], most of which involve the construction of different cost functions (usually variations or special cases and discuss applications to non-stationarity detection and natural scene statistics (NSS) modeling. Index The construction of accurate prior models of source data is essential to many applications, such as low

  3. Cognitive Science Q270, section 11246 Experiments and Models in Cognition

    E-Print Network [OSTI]

    Indiana University

    report. The project should either involve experimenting on human subjects or the formal modeling of human 11246 Experiments and Models in Cognition Fall 2009 Tu, Th 2:30-3:45, Room 228 Psychology Bldg project: 15% Lab 2 Apparent motion experiment & computational simulation: 11% Lab 3 Word perception

  4. Prediction of tree diameter growth using quantile regression and mixed-effects models

    E-Print Network [OSTI]

    Cao, Quang V.

    Prediction of tree diameter growth using quantile regression and mixed-effects models Som B. Bohora diameter predictions for the same tree in the future. Another approach considered in this study involved and mixed-effects models in predicting tree diameter growth. Tree diameter at the end of each growth period

  5. Probabilistic models for feedback systems.

    SciTech Connect (OSTI)

    Grace, Matthew D.; Boggs, Paul T.

    2011-02-01T23:59:59.000Z

    In previous work, we developed a Bayesian-based methodology to analyze the reliability of hierarchical systems. The output of the procedure is a statistical distribution of the reliability, thus allowing many questions to be answered. The principal advantage of the approach is that along with an estimate of the reliability, we also can provide statements of confidence in the results. The model is quite general in that it allows general representations of all of the distributions involved, it incorporates prior knowledge into the models, it allows errors in the 'engineered' nodes of a system to be determined by the data, and leads to the ability to determine optimal testing strategies. In this report, we provide the preliminary steps necessary to extend this approach to systems with feedback. Feedback is an essential component of 'complexity' and provides interesting challenges in modeling the time-dependent action of a feedback loop. We provide a mechanism for doing this and analyze a simple case. We then consider some extensions to more interesting examples with local control affecting the entire system. Finally, a discussion of the status of the research is also included.

  6. Modelling intonational structure using hidden markov models

    E-Print Network [OSTI]

    Wright, Helen; Taylor, Paul A

    1997-01-01T23:59:59.000Z

    A method is introduced for using hidden Markov models (HMMs) to model intonational structure. HMMs are probabilistic and can capture the variability in structure which previous finite state network models lack. We show ...

  7. Impact of a body against a rigid wall. Problem involving non-smooth and history dependent energy dissipation mechanism

    E-Print Network [OSTI]

    Zorica, Dusan; Grahovac, Nenad

    2013-01-01T23:59:59.000Z

    We study the impact of a body against a rigid wall. The body consists of a rigid block and a viscoelastic rod described by the fractional Zener model. Translatory motion of a body is influenced by the dry friction, described by the set-valued Coulomb friction law. The problem is treated analytically by the use of the Laplace transform method and solutions are obtained in a convolution form. These solutions are compared with the ones obtained by using the numerical method.

  8. Modeling Traffic Flow Emissions

    E-Print Network [OSTI]

    Cappiello, Alessandra

    2002-09-17T23:59:59.000Z

    The main topic of this thesis is the development of light-duty vehicle dynamic emission models and their integration with dynamic traffic models. Combined, these models

  9. Hydrologic Modeling Capabilities

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Management Programs has both experience and technical knowledge to use and develop Earth systems models. Hydrological Modeling Models are simplified representations of...

  10. Reaction mechanisms in aromatic hydrocarbon formation involving the C{sub 5}H{sub 5} cyclopentadienyl moiety

    SciTech Connect (OSTI)

    Melius, C.F.; Colvin, M.E. [Sandia National Labs., Livermore, CA (United States); Marinov, N.M.; Pitz, W.J. [Lawrence Livermore National Lab., CA (United States); Senkan, S.M. [Univ. of California, Los Angeles, CA (United States). Dept. of Chemical Engineering

    1996-02-01T23:59:59.000Z

    The quantum chemical BAC-MP4 and BAC-MP2 methods have been used to investigate the reaction mechanisms leading to polycyclic aromatic hydrocarbon (PAH) ring formation. In particular the authors have determined the elementary reaction steps in the conversion of two cyclopentadienyl radicals to naphthalene. This reaction mechanism is shown to be an extension of the mechanism occurring in the H atom-assisted conversion of fulvene to benzene. The net reaction involves the formation of dihydrofulvalene, which eliminates a hydrogen atom and then rearranges to form naphthalene through a series of ring closures and openings. The importance of forming the {single_bond}CR({center_dot}){single_bond}CHR{single_bond}CR{prime}{double_bond}CR{double_prime}-moiety, which can undergo rearrangement to form three-carbon-atom ring structures, is illustrated with the C{sub 4}H{sub 7} system. The ability of hydrogen atoms to migrate around the cyclopentadienyl moiety is illustrated both for methyl-cyclopentadiene, C{sub 5}H{sub 5}CH{sub 3}, and dihydrofulvalene, C{sub 5}H{sub 5}C{sub 5}H{sub 5}, as well as for their radical species, C{sub 6}H{sub 7} and C{sub 5}H{sub 5}C{sub 5}H{sub 4}. The mobility of hydrogen in the cyclopentadienyl moiety plays an important role both in providing resonance-stabilized radical products and in creating the {single_bond}CR({center_dot}){single_bond}CHR{single_bond}CR{prime}{double_bond}CR{double_prime}-moiety for ring formation. The results illustrate the radical pathway for converting five-membered rings to aromatic six-membered rings. Furthermore, the results indicate the important catalytic role of H atoms in the aromatic ring formation process.

  11. Botryllus schlosseri (Tunicata) whole colony irradiation: Do senescent zooid resorption and immunological resorption involve similar recognition events

    SciTech Connect (OSTI)

    Rinkevich, B.; Weissman, I.L. (Israel Oceanographic and Limnological Research, Haifa (Israel))

    1990-02-01T23:59:59.000Z

    The colonial tunicate Botryllus schlosseri undergoes cyclic blastogenesis where feeding zooids are senescened and resorbed and a new generation of zooids takes over the colony. When non-identical colonies come into direct contact, they either reject each other or fuse. Fusion is usually followed by the resorption of one of the partners in the chimera (immunological resorption). The striking morphological similarities between the two resorption phenomena suggest that both may involve tissue destruction following self-nonself recognition events. Here we attempt to modify these two events by whole colony gamma irradiation assays. Three sets of experiments were performed: (1) different doses of whole colony irradiation for determination of irradiation effects (110 colonies); (2) pairs of irradiated-nonirradiated isografts of clonal replicates for the potential of reconstruction of the irradiated partners (23 pairs); (3) chimeras of irradiated-nonirradiated partners for analysis of resorption hierarchy. Mortality increased with the irradiation dose. All colonies exposed to more than 5,000 rads died within 19 days, while no colony died below 2,000 rads. The average mortality periods, in days, for doses of 6,000-8,000, 5,000, and 2,500-4,000 rads were 14.4 +/- 3.1 (n = 24), 19.8 +/- 6.0 (n = 15), and 19.6 + 5.1 (n = 22), respectively. Younger colonies (3-6 months old) may survive radiation better than older ones (more than 13 months). Many morphological alterations were recorded in irradiated colonies: ampullar contraction and/or dilation, accumulation of pigment cells within ampullae, abnormal bleeding from blood vessels, sluggish blood circulation, necrotic zones, reduction in bud number, and irregularities in zooid and system structures. With doses of 3,000-4,000 rads and above, irradiation arrested the formation of new buds and interrupted normal takeover.

  12. Surface photovoltage measurements and finite element modeling of SAW devices.

    SciTech Connect (OSTI)

    Donnelly, Christine

    2012-03-01T23:59:59.000Z

    Over the course of a Summer 2011 internship with the MEMS department of Sandia National Laboratories, work was completed on two major projects. The first and main project of the summer involved taking surface photovoltage measurements for silicon samples, and using these measurements to determine surface recombination velocities and minority carrier diffusion lengths of the materials. The SPV method was used to fill gaps in the knowledge of material parameters that had not been determined successfully by other characterization methods. The second project involved creating a 2D finite element model of a surface acoustic wave device. A basic form of the model with the expected impedance response curve was completed, and the model is ready to be further developed for analysis of MEMS photonic resonator devices.

  13. Modeling direct interband tunneling. I. Bulk semiconductors

    SciTech Connect (OSTI)

    Pan, Andrew, E-mail: pandrew@ucla.edu [Department of Electrical Engineering, University of California, Los Angeles, Los Angeles, California 90095 (United States); Chui, Chi On [Department of Electrical Engineering, University of California, Los Angeles, Los Angeles, California 90095 (United States); California NanoSystems Institute, University of California, Los Angeles, Los Angeles, California 90095 (United States)

    2014-08-07T23:59:59.000Z

    Interband tunneling is frequently studied using the semiclassical Kane model, despite uncertainty about its validity. Revisiting the physical basis of this formula, we find that it neglects coupling to other bands and underestimates transverse tunneling. As a result, significant errors can arise at low and high fields for small and large gap materials, respectively. We derive a simple multiband tunneling model to correct these defects analytically without arbitrary parameters. Through extensive comparison with band structure and quantum transport calculations for bulk InGaAs, InAs, and InSb, we probe the accuracy of the Kane and multiband formulas and establish the superiority of the latter. We also show that the nonlocal average electric field should be used when applying either of these models to nonuniform potentials. Our findings are important for efficient analysis and simulation of bulk semiconductor devices involving tunneling.

  14. Pearle's Hidden-Variable Model Revisited

    E-Print Network [OSTI]

    Richard D. Gill

    2015-05-19T23:59:59.000Z

    Pearle (1970) gave an example of a local hidden variables model which exactly reproduced the singlet correlations of quantum theory, through the device of data-rejection: particles can fail to be detected in a way which depends on the hidden variables carried by the particles and on the measurement settings. If the experimenter computes correlations between measurement outcomes of particle pairs for which both particles are detected, he is actually looking at a subsample of particle pairs, determined by interaction involving both measurement settings and the hidden variables carried in the particles. We correct a mistake in Pearle's formulas (a normalization error) and more importantly show that the model is more simple than first appears. We illustrate with visualisations of the model and with a small simulation experiment, with code in the statistical programming language R included in the paper. Open problems are discussed.

  15. Topological insulators and topological nonlinear {sigma} models

    SciTech Connect (OSTI)

    Yao Hong; Lee, Dung-Hai [Department of Physics, University of California at Berkeley, Berkeley, California 94720 (United States) and Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720 (United States)

    2010-12-15T23:59:59.000Z

    In this paper we link the physics of topological nonlinear {sigma} models with that of Chern-Simons insulators. We show that corresponding to every 2n-dimensional Chern-Simons insulator there is a (n-1)-dimensional topological nonlinear {sigma} model with the Wess-Zumino-Witten term. Breaking internal symmetry in these nonlinear {sigma} models leads to nonlinear {sigma} models with the {theta} term. [This is analogous to the dimension reduction leading from 2n-dimensional Chern-Simons insulators to (2n-1) and (2n-2)-dimensional topological insulators protected by discrete symmetries.] The correspondence described in this paper allows one to derive the topological term in a theory involving fermions and order parameters (we shall referred to them as ''fermion-{sigma} models'') when the conventional gradient-expansion method fails. We also discuss the quantum number of solitons in topological nonlinear {sigma} model and the electromagnetic action of the (2n-1)-dimensional topological insulators. Throughout the paper we use a simple model to illustrate how things work.

  16. Space and Time: Wind in an Investment Planning Model

    E-Print Network [OSTI]

    Neuhoff, Karsten; Ehrenmann, A; Butler, Lucy; Cust, J; Hoexter, Harriet; Keats, Kim; Kreczko, Adam; Sinden, Graham

    2006-03-14T23:59:59.000Z

    in different regions. Given the stock of existing capacity and the new investment the model then solves for the cheapest way to dispatch the system to satisfy demand. This could also involve demand side response, which we currently model to be avail- able... , generation and wind data as described in the previous section. The model then calculates the forward looking least cost invest- ment and operation plan to serve demand. Figure 4 illustrates the resulting cumulative new build in each of the regions. 10...

  17. I&C Modeling in SPAR Models

    SciTech Connect (OSTI)

    John A. Schroeder

    2012-06-01T23:59:59.000Z

    The Standardized Plant Analysis Risk (SPAR) models for the U.S. commercial nuclear power plants currently have very limited instrumentation and control (I&C) modeling [1]. Most of the I&C components in the operating plant SPAR models are related to the reactor protection system. This was identified as a finding during the industry peer review of SPAR models. While the Emergency Safeguard Features (ESF) actuation and control system was incorporated into the Peach Bottom Unit 2 SPAR model in a recent effort [2], various approaches to expend resources for detailed I&C modeling in other SPAR models are investigated.

  18. Disease Prediction Models and Operational Readiness

    SciTech Connect (OSTI)

    Corley, Courtney D.; Pullum, Laura L.; Hartley, David M.; Benedum, Corey M.; Noonan, Christine F.; Rabinowitz, Peter M.; Lancaster, Mary J.

    2014-03-19T23:59:59.000Z

    INTRODUCTION: The objective of this manuscript is to present a systematic review of biosurveillance models that operate on select agents and can forecast the occurrence of a disease event. One of the primary goals of this research was to characterize the viability of biosurveillance models to provide operationally relevant information for decision makers to identify areas for future research. Two critical characteristics differentiate this work from other infectious disease modeling reviews. First, we reviewed models that attempted to predict the disease event, not merely its transmission dynamics. Second, we considered models involving pathogens of concern as determined by the US National Select Agent Registry (as of June 2011). Methods: We searched dozens of commercial and government databases and harvested Google search results for eligible models utilizing terms and phrases provided by public health analysts relating to biosurveillance, remote sensing, risk assessments, spatial epidemiology, and ecological niche-modeling, The publication date of search results returned are bound by the dates of coverage of each database and the date in which the search was performed, however all searching was completed by December 31, 2010. This returned 13,767 webpages and 12,152 citations. After de-duplication and removal of extraneous material, a core collection of 6,503 items was established and these publications along with their abstracts are presented in a semantic wiki at http://BioCat.pnnl.gov. Next, PNNL’s IN-SPIRE visual analytics software was used to cross-correlate these publications with the definition for a biosurveillance model resulting in the selection of 54 documents that matched the criteria resulting Ten of these documents, However, dealt purely with disease spread models, inactivation of bacteria, or the modeling of human immune system responses to pathogens rather than predicting disease events. As a result, we systematically reviewed 44 papers and the results are presented in this analysis.

  19. Combustion instability modeling and analysis

    SciTech Connect (OSTI)

    Santoro, R.J.; Yang, V.; Santavicca, D.A. [Pennsylvania State Univ., University Park, PA (United States); Sheppard, E.J. [Tuskeggee Univ., Tuskegee, AL (United States). Dept. of Aerospace Engineering

    1995-12-31T23:59:59.000Z

    It is well known that the two key elements for achieving low emissions and high performance in a gas turbine combustor are to simultaneously establish (1) a lean combustion zone for maintaining low NO{sub x} emissions and (2) rapid mixing for good ignition and flame stability. However, these requirements, when coupled with the short combustor lengths used to limit the residence time for NO formation typical of advanced gas turbine combustors, can lead to problems regarding unburned hydrocarbons (UHC) and carbon monoxide (CO) emissions, as well as the occurrence of combustion instabilities. The concurrent development of suitable analytical and numerical models that are validated with experimental studies is important for achieving this objective. A major benefit of the present research will be to provide for the first time an experimentally verified model of emissions and performance of gas turbine combustors. The present study represents a coordinated effort between industry, government and academia to investigate gas turbine combustion dynamics. Specific study areas include development of advanced diagnostics, definition of controlling phenomena, advancement of analytical and numerical modeling capabilities, and assessment of the current status of our ability to apply these tools to practical gas turbine combustors. The present work involves four tasks which address, respectively, (1) the development of a fiber-optic probe for fuel-air ratio measurements, (2) the study of combustion instability using laser-based diagnostics in a high pressure, high temperature flow reactor, (3) the development of analytical and numerical modeling capabilities for describing combustion instability which will be validated against experimental data, and (4) the preparation of a literature survey and establishment of a data base on practical experience with combustion instability.

  20. Nano-Continuum Modeling of a Nuclear Glass Specimen Altered for 25 Years

    SciTech Connect (OSTI)

    Steefel, Carl

    2014-01-06T23:59:59.000Z

    The purpose of this contribution is to report on preliminary nano-continuum scale modeling of nuclear waste glass corrosion. The focus of the modeling is an experiment involving a French glass SON68 specimen leached for 25 years in a granitic environment. In this report, we focus on capturing the nano-scale concentration profiles. We use a high resolution continuum model with a constant grid spacing of 1 nanometer to investigate the glass corrosion mechanisms.

  1. Forward Modeling of the Induction Log Response of a Fractured Geologic Formation

    E-Print Network [OSTI]

    Bray, Steven Hunter

    2013-05-02T23:59:59.000Z

    3.1 Layered Earth Model The environment used for the induction log simulations is a layered Earth model. The model consists of six layers that are assigned different thicknesses and conductivities based on the desired induction log... Tx-Rx pair has a fixed separation and is moved along a vertical profile through the subsurface taking measurements at predetermined logging points. 20 The second change to the original Seatem code involves the surrounding environment. The code...

  2. Forward Modeling of the Induction Log Response of a Fractured Geologic Formation 

    E-Print Network [OSTI]

    Bray, Steven Hunter

    2013-05-02T23:59:59.000Z

    3.1 Layered Earth Model The environment used for the induction log simulations is a layered Earth model. The model consists of six layers that are assigned different thicknesses and conductivities based on the desired induction log... Tx-Rx pair has a fixed separation and is moved along a vertical profile through the subsurface taking measurements at predetermined logging points. 20 The second change to the original Seatem code involves the surrounding environment. The code...

  3. Technical advantages and political necessity of public involvement in environmental remediation: The case of the U.S. and Russian weapons complexes

    SciTech Connect (OSTI)

    Shideler, J.C. [JK Research Associates, Inc., Arlington, VA (United States)

    1993-12-31T23:59:59.000Z

    Environmental remediation is an enormous challenge for the governments of the US, Russia, and other states in eastern and central Europe. Historically, governments have withheld issues related to nuclear weapons from public policy debate. As a result of revelations about human health impacts and environmental contamination, serious credibility problems exist for managers of weapons facilities. However, public involvement can contribute to better definition of problems, to identification of a range of potential solutions, and to increased public acceptance of outcomes. Decision makers can maximize the benefits of public involvement by integrating specific processes into their environmental remediation project planning and management.

  4. FACT SHEET: Projects with the Federal Emergency Management Agency (FEMA) CCICADA is involved in several projects in partnership with FEMA Region II (which covers NJ, NY, Puerto Rico, and the

    E-Print Network [OSTI]

    is involved in several projects in partnership with FEMA Region II (which covers NJ, NY, Puerto Rico

  5. Bringing Alaska North Slope Natural Gas to Market (released in AEO2009)

    Reports and Publications (EIA)

    2009-01-01T23:59:59.000Z

    At least three alternatives have been proposed over the years for bringing sizable volumes of natural gas from Alaska's remote North Slope to market in the lower 48 states: a pipeline interconnecting with the existing pipeline system in central Alberta, Canada; a gas-to-liquids (GTL) plant on the North Slope; and a large liquefied natural gas (LNG) export facility at Valdez, Alaska. The National Energy Modeling System (NEMS) explicitly models the pipeline and GTL options. The what if LNG option is not modeled in NEMS.

  6. Topological Massive Sigma Models

    E-Print Network [OSTI]

    N. D. Lambert

    1995-05-03T23:59:59.000Z

    In this paper we construct topological sigma models which include a potential and are related to twisted massive supersymmetric sigma models. Contrary to a previous construction these models have no central charge and do not require the manifold to admit a Killing vector. We use the topological massive sigma model constructed here to simplify the calculation of the observables. Lastly it is noted that this model can be viewed as interpolating between topological massless sigma models and topological Landau-Ginzburg models.

  7. Center for Leadership and Involvement University of Wisconsin-Madison 239 Red Gym, 716 Langdon Street Phone: 608-263-0365

    E-Print Network [OSTI]

    Wisconsin at Madison, University of

    involvement as an integral part of a University education, registers over 750 student organizations, and provides services, information, education, support, advising, and interpretation of university policies evaluations are submitted. Maintain and track the grant's budget. Provide budget updates at Review Committee

  8. CONCLUSIONS AND RECOMMENDATIONS This report summarizes the findings of a four-year research effort involving more than 4,000

    E-Print Network [OSTI]

    -year research effort involving more than 4,000 wind turbines, and aimed at better understanding bird mortality at the world's largest wind farm, the Altamont Pass Wind Resource Area. Yet, as with most research efforts, we finished with many questions remaining unanswered about the factors associated with fatalities at wind

  9. How to connect to the University of Exeter VPN service *****Important Part of the process of using the VPN service involves the automatic

    E-Print Network [OSTI]

    Mumby, Peter J.

    the VPN service involves the automatic download and installation of Juniper Network Connect software administrator rights on your computer to be able to install this software. Once this has been installed you can use it regardless of having administrator rights or not. Additionally, you can check the last page

  10. What does it take to earn a BS degree in Electrical Engineering? A BS degree in Electrical Engineering is earned through a 4-year program involving a fundamental

    E-Print Network [OSTI]

    Maxwell, Bruce D.

    What does it take to earn a BS degree in Electrical Engineering? A BS degree in Electrical Engineering is earned through a 4-year program involving a fundamental understanding of electrical and electronic circuits and systems. Electrical engineers get to work with microscopic circuit components

  11. The naval Research Laboratory has been actively involved in research in unmanned and autonomous systems since its opening in 1923. From one of the first unmanned

    E-Print Network [OSTI]

    systems since its opening in 1923. From one of the first unmanned ground vehicles to the developmentThe naval Research Laboratory has been actively involved in research in unmanned and autonomous of more than 200 prototype air, ground, underwater, and space platforms, and from smart sensors to smart

  12. Value of Citizen Science Monitoring Involving citizen scientists in the sea star wasting disease survey effort will greatly expand our spatial

    E-Print Network [OSTI]

    California at Santa Cruz, University of

    Value of Citizen Science Monitoring Involving citizen scientists in the sea star wasting disease survey effort will greatly expand our spatial and temporal coverage. Citizen science groups can collect. A researcher from the MARINe group should accompany each citizen science group in the field to assist

  13. LIGHT is involved in the pathogenesis of rheumatoid arthritis by inducing the expression of pro-inflammatory cytokines and MMP-9

    E-Print Network [OSTI]

    Lee, Won-Ha

    LIGHT is involved in the pathogenesis of rheumatoid arthritis by inducing the expression of pro inflammation and cartilage destruction.7­9 LIGHT (TNFSF14) is a member of tumor necrosis factor superfamily and is the ligand for TR2 (TNFRSF14/HVEM/ HveA/LIGHTR/ATAR) and lymphotoxin (LT)-b.10­12 LIGHT is known

  14. In Vitro Drug Sensitivity-Gene Expression Correlations Involve a Tissue of Origin C. R. Andersson, M. Fryknas, L. Rickardson, R. Larsson, A. Isaksson, and

    E-Print Network [OSTI]

    In Vitro Drug Sensitivity-Gene Expression Correlations Involve a Tissue of Origin Dependency C. R concern of chemogenomics is to associate drug activity with biological variables. Several reports have clustered cell line drug activity profiles as well as drug activity-gene expression correlation profiles

  15. Andreja Sarlah Research interests I have been involved in physical research for 4 years now. In that time I have been work-

    E-Print Network [OSTI]

    Sarlah, Andreja

    . In that time I have been work- ing in the field of liquid crystals. My main research interest has been. This is what in my opinion makes the research work interesting and what gives the assuranceAndreja Sarlah ­ Research interests I have been involved in physical research for 4 years now

  16. Lynne Ellyn is the senior vice president and chief information officer at DTE Energy (NYSE: DTE), a Detroit-based diversified energy company involved in the development and

    E-Print Network [OSTI]

    Health System Foundation, the Henry Ford Health System Quality Committee, and the DTE Energy Charitable: DTE), a Detroit-based diversified energy company involved in the development and management of energy of Management in Information Technology Advisory Board. She serves on the board of trustees of the Henry Ford

  17. Runtime Tracing of The Community Earth System Model: Feasibility and Benefits

    SciTech Connect (OSTI)

    Wang, Dali [ORNL] [ORNL; Domke, Jens [ORNL] [ORNL

    2011-01-01T23:59:59.000Z

    Community Earth System Models (CESM) is one of US's leading earth system modeling systems, which has over decades of development history and embraced by large, active user communities. In this paper, we first review the history of CESM software development and layout the general objectives of performance analysis. Then we present an offline global community land model simulation within the CESM framework to demonstrate the procedure of runtime tracing of CESM using the Vampir toolset. Finally, we explain the benefits of runtime tracing to the general earth system modeling community. We hope those considerations can also be beneficial to many other modeling research programs involving legacy high-performance computing applications.

  18. Non-LTE Balmer line formation in late-type spectra: Effects of atomic processes involving hydrogen atoms

    E-Print Network [OSTI]

    P. S. Barklem

    2007-02-08T23:59:59.000Z

    (*** abridged ***) Context: The wings of Balmer lines are often used as effective temperature diagnostics for late-type stars under the assumption they form in local thermodynamic equilibrium. Aims: Our goal is to investigate the non-LTE formation of Balmer lines in late-type stellar atmospheres, to establish if the assumption of LTE is justified. Furthermore, we aim to determine which collision processes are important for the problem; in particular, the role of collision processes with hydrogen atoms is investigated. Method: A model hydrogen atom for non-LTE calculations has been constructed accounting for various collision processes using the best available data from the literature. The processes included are inelastic collisions with electrons and hydrogen atoms, mutual neutralisation and Penning ionisation. Non-LTE calculations are performed, and the relative importance of the collision processes is investigated. Results: Our calculations show electron collisions alone are not sufficient to establish LTE for the formation of Balmer line wings. The role of inelastic collisions with neutral hydrogen is unclear. The available data for these processes is of questionable quality, and different prescriptions for the rate coefficents give significantly different results for the Balmer line wings. Conclusions: Improved calculations or experimental data are needed for excitation and, particularly, ionisation of hydrogen atoms in low-lying states by hydrogen atom impact at near threshold energies. Until such data are available, the assumption of LTE for the formation of Balmer line wings in late-type stars is questionable.

  19. Development of long-term performance models for radioactive waste forms

    SciTech Connect (OSTI)

    Bacon, Diana H.; Pierce, Eric M.

    2011-03-22T23:59:59.000Z

    The long-term performance of solid radioactive waste is measured by the release rate of radionuclides into the environment, which depends on corrosion or weathering rates of the solid waste form. The reactions involved depend on the characteristics of the solid matrix containing the radioactive waste, the radionuclides of interest, and their interaction with surrounding geologic materials. This chapter describes thermo-hydro-mechanical and reactive transport models related to the long-term performance of solid radioactive waste forms, including metal, ceramic, glass, steam reformer and cement. Future trends involving Monte-Carlo simulations and coupled/multi-scale process modeling are also discussed.

  20. A Relativistic Dynamical Collapse Model

    E-Print Network [OSTI]

    Philip Pearle

    2014-12-21T23:59:59.000Z

    A model is discussed where all operators are constructed from a quantum scalar field whose energy spectrum takes on all real values. The Schr\\"odinger picture wave function depends upon space and time coordinates for each particle, as well as an inexorably increasing evolution parameter $s$ which labels a foliation of space-like hypersurfaces. The model is constructed to be manifestly Lorentz invariant in the interaction picture. Free particle states and interactions are discussed in this framework. Then, the formalism of the CSL (Continuous Spontaneous Localization) theory of dynamical collapse is applied. The collapse-generating operator is chosen to to be the particle number space-time density. Unlike previous relativistically invariant models, the vacuum state is not excited. The collapse dynamics depends upon two parameters, a parameter $\\Lambda$ which represents the collapse rate/volume and a scale factor $\\ell$. A common example of collapse dynamics, involving a clump of matter in a superposition of two locations, is analyzed. The collapse rate is shown to be identical to that of non-relativistic CSL when the GRW-CSL choice of $\\ell=a=10^{-5}$cm, is made, along with $\\Lambda=\\lambda/a^{3}$ (GRW-CSL choice $\\lambda=10^{-16}s^{-1}$). However, it is also shown that the change of mass of a nucleon over the age of the universe is then unacceptably large. The case where $\\ell$ is the size of the universe is then considered. It is shown that the collapse behavior is satisfactory and the change of mass over the age of the universe is acceptably small, when $\\Lambda= \\lambda/\\ell a^{2}$.