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  1. National Energy Modeling System (NEMS)

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    The National Energy Modeling System (NEMS) is a computer-based, energy-economy modeling system of U.S. through 2030. NEMS projects the production, imports, conversion, consumption, and prices of energy, subject to assumptions on macroeconomic and financial factors, world energy markets, resource availability and costs, behavioral and technological choice criteria, cost and performance characteristics of energy technologies, and demographics. NEMS was designed and implemented by the Energy Information Administration (EIA) of the U.S. Department of Energy (DOE). NEMS can be used to analyze the effects of existing and proposed government laws and regulations related to energy production and use; the potential impact of new and advanced energy production, conversion, and consumption technologies; the impact and cost of greenhouse gas control; the impact of increased use of renewable energy sources; and the potential savings from increased efficiency of energy use; and the impact of regulations on the use of alternative or reformulated fuels. NEMS has also been used for a number of special analyses at the request of the Administration, U.S. Congress, other offices of DOE and other government agencies, who specify the scenarios and assumptions for the analysis. Modules allow analyses to be conducted in energy topic areas such as residential demand, industrial demand, electricity market, oil and gas supply, renewable fuels, etc.

  2. How to obtain the National Energy Modeling System (NEMS)

    Reports and Publications (EIA)

    2013-01-01

    The National Energy Modeling System (NEMS) NEMS is used by the modelers at the U. S. Energy Information Administration (EIA) who understand its structure and programming. NEMS has only been used by a few organizations outside of the EIA, because most people that requested NEMS found out that it was too difficult or rigid to use. NEMS is not typically used for state-level analysis and is poorly suited for application to other countries. However, many do obtain the model simply to use the data in its input files or to examine the source code.

  3. Price Responsiveness in the AEO2003 NEMS Residential and Commercial Buildings Sector Models

    Reports and Publications (EIA)

    2003-01-01

    This paper describes the demand responses to changes in energy prices in the Annual Energy Outlook 2003 versions of the Residential and Commercial Demand Modules of the National Energy Modeling System (NEMS). It updates a similar paper completed for the Annual Energy Outlook 1999 version of the NEMS.

  4. Modeling Distributed Electricity Generation in the NEMS Buildings Models

    Reports and Publications (EIA)

    2011-01-01

    This paper presents the modeling methodology, projected market penetration, and impact of distributed generation with respect to offsetting future electricity needs and carbon dioxide emissions in the residential and commercial buildings sector in the Annual Energy Outlook 2000 (AEO2000) reference case.

  5. International Energy Module - NEMS Documentation

    Reports and Publications (EIA)

    2014-01-01

    Summarizes the overall structure of the International Energy Model and its interface with other NEMS modules, mathematical specifications of behavioral relationships, and data sources and estimation methods.

  6. NEMS International Energy Module, model documentation report: World Oil Market, Petroleum Products Supply and Oxygenates Supply components

    SciTech Connect (OSTI)

    Not Available

    1994-04-04

    The Energy Information Administration (EIA) is developing the National Energy Modeling System (NEMS) to enhance its energy forecasting capabilities and to provide the Department of Energy with a comprehensive framework for analyzing alternative energy` futures. NEMS is designed with a multi-level modular structure that represents specific energy supply activities, conversion processes, and demand sectors as a series of self-contained units which are linked by an integrating mechanism. The NEMS International Energy Module (IEM) computes world oil prices and the resulting patterns of international trade in crude oil and refined products. This report is a reference document for energy analysts, model users, and the public that is intended to meet EIA`s legal obligation to provide adequate documentation for all statistical and forecast reports (Public Law 93-275, section 57(b)(1). Its purpose is to describe the structure of the IEM. Actual operation of the model is not discussed here. The report contains four sections summarizing the overall structure of the IEM and its interface with other NEMS modules, mathematical specifications of behavioral relationships, and data sources and estimation methods. Following a general description of the function and rationale of its key components, system and equation level information sufficient to permit independent evaluation of the model`s technical details is presented.

  7. Residential Demand Module - NEMS Documentation

    Reports and Publications (EIA)

    2014-01-01

    Model Documentation - Documents the objectives, analytical approach, and development of the National Energy Modeling System (NEMS) Residential Sector Demand Module. The report catalogues and describes the model assumptions, computational methodology, parameter estimation techniques, and FORTRAN source code.

  8. Renewable Fuels Module - NEMS Documentation

    Reports and Publications (EIA)

    2014-01-01

    This report documents the objectives, analytical approach, and design of the National Energy Modeling System (NEMS) Renewable Fuels Module (RFM) as it relates to the production of the Annual Energy Outlook forecasts.

  9. NEMS integrating module documentation report

    SciTech Connect (OSTI)

    Not Available

    1993-12-14

    The National Energy Modeling System (NEMS) is a computer modeling system that produces a general equilibrium solution for energy supply and demand in the US energy markets. The model achieves a supply and demand balance in the end-use demand regions, defined as the nine Census Divisions, by solving for the prices of each energy type such that the quantities producers are willing to supply equal the quantities consumers wish to consume. The system reflects market economics, industry structure, and energy policies and regulations that influence market behavior. The NEMS Integrating Module is the central integrating component of a complex modeling system. As such, a thorough understanding of its role in the modeling process can only be achieved by placing it in the proper context with respect to the other modules. To that end, this document provides an overview of the complete NEMS model, and includes brief descriptions of the modules with which the Integrating Module interacts. The emphasis and focus, however, is on the structure and function of the Integrating Module of NEMS.

  10. National Energy Modeling System with Hydrogen Model (NEMS-H2)

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious Rank EERE:Financing Tool Fits the BillDepartmentSites KDF SocialAdministratorNSIDCNatModeling System with

  11. Macroeconomic Activity Module - NEMS Documentation

    Reports and Publications (EIA)

    2014-01-01

    Documents the objectives, analytical approach, and development of the National Energy Modeling System (NEMS) Macroeconomic Activity Module (MAM) used to develop the Annual Energy Outlook for 2014 (AEO2014). The report catalogues and describes the module assumptions, computations, methodology, parameter estimation techniques, and mainframe source code

  12. Coal Market Module - NEMS Documentation

    Reports and Publications (EIA)

    2014-01-01

    Documents the objectives and the conceptual and methodological approach used in the development of the National Energy Modeling System's (NEMS) Coal Market Module (CMM) used to develop the Annual Energy Outlook 2014 (AEO2014). This report catalogues and describes the assumptions, methodology, estimation techniques, and source code of CMM's two submodules. These are the Coal Production Submodule (CPS) and the Coal Distribution Submodule (CDS).

  13. Assessment and Suggestions to Improve the Commercial Building Module of EIA-NEMS 

    E-Print Network [OSTI]

    O'Neal, D. L.; Reddy, T. A.; Sucher, B.

    1996-01-01

    The National Energy Modeling System (NEMS) is a comprehensive, computer-based, energy-economy modeling system developed and maintained by the Department of Energy's Energy Information Administration (EIA). NEMS forecasts the national production...

  14. U.S. Regional Demand Forecasts Using NEMS and GIS

    SciTech Connect (OSTI)

    Cohen, Jesse A.; Edwards, Jennifer L.; Marnay, Chris

    2005-07-01

    The National Energy Modeling System (NEMS) is a multi-sector, integrated model of the U.S. energy system put out by the Department of Energy's Energy Information Administration. NEMS is used to produce the annual 20-year forecast of U.S. energy use aggregated to the nine-region census division level. The research objective was to disaggregate this regional energy forecast to the county level for select forecast years, for use in a more detailed and accurate regional analysis of energy usage across the U.S. The process of disaggregation using a geographic information system (GIS) was researched and a model was created utilizing available population forecasts and climate zone data. The model's primary purpose was to generate an energy demand forecast with greater spatial resolution than what is currently produced by NEMS, and to produce a flexible model that can be used repeatedly as an add-on to NEMS in which detailed analysis can be executed exogenously with results fed back into the NEMS data flow. The methods developed were then applied to the study data to obtain residential and commercial electricity demand forecasts. The model was subjected to comparative and statistical testing to assess predictive accuracy. Forecasts using this model were robust and accurate in slow-growing, temperate regions such as the Midwest and Mountain regions. Interestingly, however, the model performed with less accuracy in the Pacific and Northwest regions of the country where population growth was more active. In the future more refined methods will be necessary to improve the accuracy of these forecasts. The disaggregation method was written into a flexible tool within the ArcGIS environment which enables the user to output the results in five year intervals over the period 2000-2025. In addition, the outputs of this tool were used to develop a time-series simulation showing the temporal changes in electricity forecasts in terms of absolute, per capita, and density of demand.

  15. Comparison of Bottom-Up and Top-Down Forecasts: Vision Industry Energy Forecasts with ITEMS and NEMS 

    E-Print Network [OSTI]

    Roop, J. M.; Dahowski, R. T

    2000-01-01

    Comparisons are made of energy forecasts using results from the Industrial module of the National Energy Modeling System (NEMS) and an industrial economic-engineering model called the Industrial Technology and Energy Modeling System (ITEMS), a model...

  16. U.S. Regional Demand Forecasts Using NEMS and GIS

    E-Print Network [OSTI]

    Cohen, Jesse A.; Edwards, Jennifer L.; Marnay, Chris

    2005-01-01

    Forecasts Using NEMS and GIS National Climatic Data Center.with Changing Boundaries." Use of GIS to Understand Socio-Forecasts Using NEMS and GIS Appendix A. Map Results Gallery

  17. Integrated NEMS and optoelectronics for sensor applications.

    SciTech Connect (OSTI)

    Czaplewski, David A.; Serkland, Darwin Keith; Olsson, Roy H., III; Bogart, Gregory R. (Symphony Acoustics, Rio Rancho, NM); Krishnamoorthy, Uma; Warren, Mial E.; Carr, Dustin Wade (Symphony Acoustics, Rio Rancho, NM); Okandan, Murat; Peterson, Kenneth Allen

    2008-01-01

    This work utilized advanced engineering in several fields to find solutions to the challenges presented by the integration of MEMS/NEMS with optoelectronics to realize a compact sensor system, comprised of a microfabricated sensor, VCSEL, and photodiode. By utilizing microfabrication techniques in the realization of the MEMS/NEMS component, the VCSEL and the photodiode, the system would be small in size and require less power than a macro-sized component. The work focused on two technologies, accelerometers and microphones, leveraged from other LDRD programs. The first technology was the nano-g accelerometer using a nanophotonic motion detection system (67023). This accelerometer had measured sensitivity of approximately 10 nano-g. The Integrated NEMS and optoelectronics LDRD supported the nano-g accelerometer LDRD by providing advanced designs for the accelerometers, packaging, and a detection scheme to encapsulate the accelerometer, furthering the testing capabilities beyond bench-top tests. A fully packaged and tested die was never realized, but significant packaging issues were addressed and many resolved. The second technology supported by this work was the ultrasensitive directional microphone arrays for military operations in urban terrain and future combat systems (93518). This application utilized a diffraction-based sensing technique with different optical component placement and a different detection scheme from the nano-g accelerometer. The Integrated NEMS LDRD supported the microphone array LDRD by providing custom designs, VCSELs, and measurement techniques to accelerometers that were fabricated from the same operational principles as the microphones, but contain proof masses for acceleration transduction. These devices were packaged at the end of the work.

  18. Investigation of the effects of soluble boron tracking on coupled CTF / NEM, LWR simulations

    SciTech Connect (OSTI)

    Biery, M.; Avramova, M.; Ivanov, K.

    2013-07-01

    The primary objective of this study is to evaluate the effects of introducing a boron tracking capability to the COBRA-TF / NEM code coupling. The Pennsylvania State University (PSU) versions of COBRA-TF - CTF, and Nodal Expansion Method (NEM) codes are utilized. Previous implementations of the CTF / NEM coupled code had no capability to model soluble boron feedback effects due to boron transport. This study builds upon the validation and qualification efforts of the boron tracking model implementation in CTF by modeling the boron feedback calculated by the CTF boron tracking model in NEM. The core model chosen for this study is the Purdue MOX/UO{sub 2} core model used in the 2007 OECD/NRC code benchmark study. Following the implementation of an explicit online coupling scheme and accompanying k-search routine, the newly coupled CTF / NEM code version with boron tracking is compared to prior results of the non-boron tracking CTF / NEM code version at steady-state hot full power and hot zero power conditions. It was found that the boron tracking model exhibited little influence on the hot zero power result as expected due to a smaller heat flux, which does not significantly change the moderator density and boron concentration as the moderator travels up the axial core length. Meanwhile the boron tracking model had a much greater impact on the hot full power results, predicting the critical inlet boron concentration to be 9.9 ppm below the non-boron tracking result due to greater and more rapid changes in boron concentration corresponding to the reduction in moderator density from being more rapidly heated. (authors)

  19. NEMS Freight Transportation Module Improvement Study

    Gasoline and Diesel Fuel Update (EIA)

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  20. NEMS Buildings Sector Working Group Meeting

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustments (Billion Cubic Feet) Wyoming963Residential2, 2014ProvedYear Jan Feb Mar AprCubic Feet)Rowe:NEMS

  1. Investigation of residential central air conditioning load shapes in NEMS

    E-Print Network [OSTI]

    Hamachi LaCommare, Kristina; Marnay, Chris; Gumerman, Etan; Chan, Peter; Rosenquist, Greg; Osborn, Julie

    2002-01-01

    of Residential Central Air Conditioning Load Shapes in NEMSof Residential Central Air Conditioning Load Shapes in NEMSof Residential Central Air Conditioning Load Shapes in NEMS

  2. Liquid Fuels Market Module - NEMS Documentation

    Reports and Publications (EIA)

    2014-01-01

    Defines the objectives of the Liquid Fuels Market Model (LFMM), describes its basic approach, and provides detail on how it works. This report is intended as a reference document for model analysts, users, and the public.

  3. Floating-point unit (FPU) designs with nano-electromechanical (NEM) relays

    E-Print Network [OSTI]

    Dutta, Sumit, S.M. Massachusetts Institute of Technology

    2013-01-01

    Nano-electromechanical (NEM) relays are an alternative to CMOS transistors as the fabric of digital circuits. Circuits with NEM relays offer energy-efficiency benefits over CMOS since they have zero leakage power and are ...

  4. A sensitivity analysis of the treatment of wind energy in the AEO99 version of NEMS

    SciTech Connect (OSTI)

    Osborn, Julie G; Wood, Frances; Richey, Cooper; Sanders, Sandy; Short, Walter; Koomey, Jonathan

    2001-01-01

    Each year, the U.S. Department of Energy's Energy Information Administration (EIA) publishes a forecast of the domestic energy economy in the Annual Energy Outlook (AEO). During the forecast period of the AEO (currently through 2020), renewable energy technologies have typically not achieved significant growth. The contribution of renewable technologies as electric generators becomes more important, however, in scenarios analyzing greenhouse gas emissions reductions or significant technological advancements. We examined the economic assumptions about wind power used for producing forecasts with the National Energy Modeling System (NEMS) to determine their influence on the projected capacity expansion of this technology. This analysis should help illustrate to policymakers what types of issues may affect wind development, and improve the general understanding of the NEMS model itself. Figure 1 illustrates the model structure and factors relevant to wind deployment. We found that NEMS uses various cost multipliers and constraints to represent potential physical and economic limitations to growth in wind capacity, such as resource depletion, costs associated with rapid manufacturing expansion, and grid stability with high levels of capacity from intermittent resources. The model's flexibility allows the user to make alternative assumptions about the magnitude of these factors. While these assumptions have little effect on the Reference Case forecast for the 1999 edition of the AEO, they can make a dramatic difference when wind is more attractive, such as under a carbon permit trading system. With $100/ton carbon permits, the wind capacity projection for 2020 ranges from 15 GW in the unaltered model (AEO99 Reference Case) to 168 GW in the extreme case when all the multipliers and constraints examined in this study are removed. Furthermore, if modifications are made to the model allowing inter-regional transmission of electricity, wind capacity is forecast to reach 214 GW when all limitations are removed. The figures in the upper end of these ranges are not intended to be viewed as reasonable projections, but their magnitude illustrates the importance of the parameters governing the growth of wind capacity and resource availability in forecasts using NEMS. In addition, many uncertainties exist regarding these assumptions that potentially affect the growth of wind power. We suggest several areas in which to focus future research in order to better model the potential development of this resource. Because many of the assumptions related to wind in the model are also used for other renewable technologies, these suggestions could be applied to other renewable resources as well.

  5. Appendix E: Other NEMS-MP results for the base case and scenarios.

    SciTech Connect (OSTI)

    Plotkin, S. E.; Singh, M. K.; Energy Systems

    2009-12-03

    The NEMS-MP model generates numerous results for each run of a scenario. (This model is the integrated National Energy Modeling System [NEMS] version used for the Multi-Path Transportation Futures Study [MP].) This appendix examines additional findings beyond the primary results reported in the Multi-Path Transportation Futures Study: Vehicle Characterization and Scenario Analyses (Reference 1). These additional results are provided in order to help further illuminate some of the primary results. Specifically discussed in this appendix are: (1) Energy use results for light vehicles (LVs), including details about the underlying total vehicle miles traveled (VMT), the average vehicle fuel economy, and the volumes of the different fuels used; (2) Resource fuels and their use in the production of ethanol, hydrogen (H{sub 2}), and electricity; (3) Ethanol use in the scenarios (i.e., the ethanol consumption in E85 vs. other blends, the percent of travel by flex fuel vehicles on E85, etc.); (4) Relative availability of E85 and H2 stations; (5) Fuel prices; (6) Vehicle prices; and (7) Consumer savings. These results are discussed as follows: (1) The three scenarios (Mixed, (P)HEV & Ethanol, and H2 Success) when assuming vehicle prices developed through literature review; (2) The three scenarios with vehicle prices that incorporate the achievement of the U.S. Department of Energy (DOE) program vehicle cost goals; (3) The three scenarios with 'literature review' vehicle prices, plus vehicle subsidies; and (4) The three scenarios with 'program goals' vehicle prices, plus vehicle subsidies. The four versions or cases of each scenario are referred to as: Literature Review No Subsidies, Program Goals No Subsidies, Literature Review with Subsidies, and Program Goals with Subsidies. Two additional points must be made here. First, none of the results presented for LVs in this section include Class 2B trucks. Results for this class are included occasionally in Reference 1. They represent a small, though noticeable, segment of the 'LV plus 2B' market (e.g., a little more than 3% of today's energy use in that market). We generally do not include them in this discussion, simply because it requires additional effort to combine the NEMS-MP results for them with the results for the other LVs. (Where there is an exception, we will indicate so.) Second, where reference is made to E85, the ethanol content is actually 74%. The Energy Information Administration (EIA) assumes that, to address cold-starting issues, the percent of ethanol in E85 will vary seasonally. The EIA uses an annual average ethanol content of 74% in its forecasts. That assumption is maintained in the NEMS-MP scenario runs.

  6. Overview of NEMS-H2, Version 1.0

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious RankADVANCED MANUFACTURINGEnergy Bills andOrder 422.1, CONDUCT OFER-B-00-020 DOEProgramNEMS-H2, Version 1.0

  7. National Energy Modeling System (NEMS) | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on QA:QAsource History ViewMayo, Maryland:NPI Ventures Ltd Jump to: navigation,Naples,Development and

  8. Energy Information Administration NEMS Petroleum Market Model Documentation

    Gasoline and Diesel Fuel Update (EIA)

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  9. The Practical Applications of Net Energy Metering (NEM) By: Ken Linder and Katie Noland

    E-Print Network [OSTI]

    Maxwell, Bruce D.

    Applications of Net Energy Metering (NEM) By: Ken Linder and Katie Noland Recommendations: Currently the Net Energy Metering (NEM) law in accordance to Montana state policy caps the amount of energy reimbursable by utility companies for personal production of energy. The goal of the capstone class policy group is to put

  10. A sensitivity analysis of the treatment of wind energy in the AEO99 version of NEMS

    E-Print Network [OSTI]

    Osborn, Julie G.; Wood, Frances; Richey, Cooper; Sanders, Sandy; Short, Walter; Koomey, Jonathan

    2001-01-01

    Documentation Report: Wind Energy Submodule (WES). DOE/EIA-The Economic Value of Wind Energy at High Power SystemOF THE TREATMENT OF WIND ENERGY IN THE AEO99 VERSION OF NEMS

  11. CNT-based MEMS/NEMS gas ionizers for portable mass spectrometry applications

    E-Print Network [OSTI]

    Velasquez-Heller, Luis Fernand

    We report the fabrication and experimental characterization of a carbon nanotube (CNT)-based MEMS/NEMS electron impact gas ionizer with an integrated extractor gate for portable mass spectrometry. The ionizer achieves ...

  12. Directory of Energy Information Administration Models 1993

    SciTech Connect (OSTI)

    Not Available

    1993-07-06

    This directory contains descriptions about each model, including the title, acronym, purpose, followed by more detailed information on characteristics, uses, and requirements. Sources for additional information are identified. Included in this directory are 35 EIA models active as of May 1, 1993. Models that run on personal computers are identified by ``PC`` as part of the acronym. EIA is developing new models, a National Energy Modeling System (NEMS), and is making changes to existing models to include new technologies, environmental issues, conservation, and renewables, as well as extend forecast horizon. Other parts of the Department are involved in this modeling effort. A fully operational model is planned which will integrate completed segments of NEMS for its first official application--preparation of EIA`s Annual Energy Outlook 1994. Abstracts for the new models will be included in next year`s version of this directory.

  13. H Loop shaping control for PLL-based mechanical resonance tracking in NEMS resonant mass sensors

    E-Print Network [OSTI]

    Boyer, Edmond

    problem that rejects the disturbance described by the resonance frequency shift, attenuates the phase the measurement scheme to a disturbance rejection control issue which considers the resonance frequency variation--A simple dynamic detection of the resonance frequency shift in NEMS resonant mass sensors is described

  14. MEMS/NEMS Design Automation and Synthesis Annual Report for NSF Grant # CCR-DES/CC-0306557

    E-Print Network [OSTI]

    Agogino, Alice M.

    1 MEMS/NEMS Design Automation and Synthesis Annual Report for NSF Grant # CCR-DES/CC-0306557 (2004: The goal of the project is to extend the existing SUGAR MEMS simulator into a design synthesis tool that supports the early stages of MEMS/NEMS conceptual design. We are developing a broad base of MEMS building

  15. MEMS/NEMS Design Automation and Synthesis Annual Report for NSF Grant # CCR-DES/CC-0306557

    E-Print Network [OSTI]

    Agogino, Alice M.

    1 MEMS/NEMS Design Automation and Synthesis Annual Report for NSF Grant # CCR-DES/CC-0306557 (2005: The goal of the project is to extend the existing SUGAR MEMS simulator into a design synthesis tool that supports the early stages of MEMS/NEMS conceptual design. We are developing a broad base of MEMS building

  16. Ultrananocrystalline and nanocrystalline diamond thin films for NEMS/MEMS applications.

    SciTech Connect (OSTI)

    Sumant, A. V.; Auciello, O.; Carpick, R. W.; Srinivasan, S.; Butler, J. E. (Center for Nanoscale Materials); ( MSD); ( PSC-USR)

    2010-04-01

    There has been a tireless quest by the designers of micro- and nanoelectro mechanical systems (MEMS/NEMS) to find a suitable material alternative to conventional silicon. This is needed to develop robust, reliable, and long-endurance MEMS/NEMS with capabilities for working under demanding conditions, including harsh environments, high stresses, or with contacting and sliding surfaces. Diamond is one of the most promising candidates for this because of its superior physical, chemical, and tribomechanical properties. Ultrananocrystalline diamond (UNCD) and nanocrystalline diamond (NCD) thin films, the two most studied forms of diamond films in the last decade, have distinct growth processes and nanostructures but complementary properties. This article reviews the fundamental and applied science performed to understand key aspects of UNCD and NCD films, including the nucleation and growth, tribomechanical properties, electronic properties, and applied studies on integration with piezoelectric materials and CMOS technology. Several emerging diamond-based MEMS/NEMS applications, including high-frequency resonators, radio frequency MEMS and photonic switches, and the first commercial diamond MEMS product - monolithic diamond atomic force microscopy probes - are discussed.

  17. Pore scale modeling of reactive transport involved in geologic CO2 sequestration

    SciTech Connect (OSTI)

    Kang, Qinjin [Los Alamos National Laboratory; Lichtner, Peter C [Los Alamos National Laboratory; Viswanathan, Hari S [Los Alamos National Laboratory; Abdel-fattah, Amr I [Los Alamos National Laboratory

    2009-01-01

    We apply a multi-component reactive transport lattice Boltzmann model developed in previolls studies to modeling the injection of a C02 saturated brine into various porous media structures at temperature T=25 and 80 C. The porous media are originally consisted of calcite. A chemical system consisting of Na+, Ca2+, Mg2+, H+, CO2(aq), and CI-is considered. The fluid flow, advection and diHusion of aqueous species, homogeneous reactions occurring in the bulk fluid, as weB as the dissolution of calcite and precipitation of dolomite are simulated at the pore scale. The effects of porous media structure on reactive transport are investigated. The results are compared with continuum scale modeling and the agreement and discrepancy are discussed. This work may shed some light on the fundamental physics occurring at the pore scale for reactive transport involved in geologic C02 sequestration.

  18. Modeling of battery energy storage in the National Energy Modeling System

    SciTech Connect (OSTI)

    Swaminathan, S.; Flynn, W.T.; Sen, R.K.

    1997-12-01

    The National Energy Modeling System (NEMS) developed by the U.S. Department of Energy`s Energy Information Administration is a well-recognized model that is used to project the potential impact of new electric generation technologies. The NEMS model does not presently have the capability to model energy storage on the national grid. The scope of this study was to assess the feasibility of, and make recommendations for, the modeling of battery energy storage systems in the Electricity Market of the NEMS. Incorporating storage within the NEMS will allow the national benefits of storage technologies to be evaluated.

  19. Fundamentals and application of materials integration for low-power piezoelectrically actuated ultra-nanocrystalline diamond MEMS/NEMS.

    SciTech Connect (OSTI)

    Auciello, O.; Srinivasan, S.; Hiller, J.; Kabius, B. (Center for Nanoscale Materials); ( MSD)

    2009-01-01

    Most current micro/nanoelectromechanical systems (MEMS/NEMS) are based on silicon. However, silicon exhibits relatively poor mechanical/tribological properties, compromising applications to several projected MEMS/NEMS devices, particularly those that require materials with high Young's modulus for MEMS resonators or low surface adhesion forces for MEMS/NEMS working in conditions with extensive surface contact. Diamond films with superior mechanical/tribological properties provide an excellent alternative platform material. Ultrananocrystalline diamond (UNCD{cflx W}) in film form with 2-5 nm grains exhibits excellent properties for high-performance MEMS/NEMS devices. Concurrently, piezoelectric Pb(Zr{sub x}Ti{sub 1-x})O{sub 3} (PZT) films provide high sensitivity/low electrical noise for sensing/high-force actuation at relatively low voltages. Therefore, integration of PZT and UNCD films provides a high-performance platform for advanced MEMS/NEMS devices. This paper describes the bases of such integration and demonstration of low voltage piezoactuated hybrid PZT/UNCD cantilevers.

  20. Brief Narrative Description of Research, Teaching, and Service Interests Research: My research involves modeling time-to-event data using flowgraph models.

    E-Print Network [OSTI]

    Huzurbazar, Aparna V.

    for Project AIR FORCE. The main projects involved issues in fleet assessment and programmed depot maintenance, Statistical Inference, Survival Analysis and Logistic Regression, Linear Models, Multivariate Analysis

  1. Appendix A: GPRA08 benefits estimates: NEMS and MARKAL Model Baseline Cases

    SciTech Connect (OSTI)

    None, None

    2009-01-18

    Document summarizes the results of the benefits analysis of EERE’s programs, as described in the FY 2008 Budget Request. EERE estimates benefits for its overall portfolio and nine Research, Development, Demonstration, and Deployment (RD3) programs.

  2. Learning and cost reductions for generating technologies in the national energy modeling system (NEMS)

    E-Print Network [OSTI]

    Gumerman, Etan; Marnay, Chris

    2004-01-01

    of International Learning on Technology Cost. In Issues ofbetween initial new technology cost estimates and actualthe revolutionary technologies have cost reductions beyond

  3. Model documentation: Electricity Market Module, Electricity Capacity Planning submodule

    SciTech Connect (OSTI)

    Not Available

    1994-04-07

    The National Energy Modeling System (NEMS) is a computer modeling system developed by the Energy Information Administration (EIA). The NEMS produces integrated forecasts for energy markets in the United States by achieving a general equilibrium solution for energy supply and demand. Currently, for each year during the period from 1990 through 2010, the NEMS describes energy supply, conversion, consumption, and pricing. The Electricity Market Module (EMM) is the electricity supply component of the National Energy Modeling System (NEMS). The supply of electricity is a conversion activity since electricity is produced from other energy sources (e.g., fossil, nuclear, and renewable). The EMM represents the generation, transmission, and pricing of electricity. The EMM consists of four main submodules: Electricity Capacity Planning (ECP), Electricity Fuel Dispatching (EFD), Electricity Finance and Pricing (EFP), and Load and Demand-Side Management (LDSM). The ECP evaluates changes in the mix of generating capacity that are necessary to meet future demands for electricity and comply with environmental regulations. The EFD represents dispatching (i.e., operating) decisions and determines how to allocate available capacity to meet the current demand for electricity. Using investment expenditures from the ECP and operating costs from the EFD, the EFP calculates the price of electricity, accounting for state-level regulations involving the allocation of costs. The LDSM translates annual demands for electricity into distributions that describe hourly, seasonal, and time-of-day variations. These distributions are used by the EFD and the ECP to determine the quantity and types of generating capacity that are required to insure reliable and economical supplies of electricity. The EMM also represents nonutility suppliers and interregional and international transmission and trade. These activities are included in the EFD and the ECP.

  4. A 2D/1D coupling neutron transport method based on the matrix MOC and NEM methods

    SciTech Connect (OSTI)

    Zhang, H.; Zheng, Y.; Wu, H.; Cao, L.

    2013-07-01

    A new 2D/1D coupling method based on the matrix MOC method (MMOC) and nodal expansion method (NEM) is proposed for solving the three-dimensional heterogeneous neutron transport problem. The MMOC method, used for radial two-dimensional calculation, constructs a response matrix between source and flux with only one sweep and then solves the linear system by using the restarted GMRES algorithm instead of the traditional trajectory sweeping process during within-group iteration for angular flux update. Long characteristics are generated by using the customization of commercial software AutoCAD. A one-dimensional diffusion calculation is carried out in the axial direction by employing the NEM method. The 2D and ID solutions are coupled through the transverse leakage items. The 3D CMFD method is used to ensure the global neutron balance and adjust the different convergence properties of the radial and axial solvers. A computational code is developed based on these theories. Two benchmarks are calculated to verify the coupling method and the code. It is observed that the corresponding numerical results agree well with references, which indicates that the new method is capable of solving the 3D heterogeneous neutron transport problem directly. (authors)

  5. Natural gas transmission and distribution model of the National Energy Modeling System

    SciTech Connect (OSTI)

    1997-02-01

    The Natural Gas Transmission and Distribution Model (NGTDM) is the component of the National Energy Modeling System (NEMS) that is used to represent the domestic natural gas transmission and distribution system. NEMS was developed in the Office of Integrated Analysis and Forecasting of the Energy Information Administration (EIA). NEMS is the third in a series of computer-based, midterm energy modeling systems used since 1974 by the EIA and its predecessor, the Federal Energy Administration, to analyze domestic energy-economy markets and develop projections. From 1982 through 1993, the Intermediate Future Forecasting System (IFFS) was used by the EIA for its analyses, and the Gas Analysis Modeling System (GAMS) was used within IFFS to represent natural gas markets. Prior to 1982, the Midterm Energy Forecasting System (MEFS), also referred to as the Project Independence Evaluation System (PIES), was employed. NEMS was developed to enhance and update EIA`s modeling capability by internally incorporating models of energy markets that had previously been analyzed off-line. In addition, greater structural detail in NEMS permits the analysis of a broader range of energy issues. The time horizon of NEMS is the midterm period (i.e., through 2015). In order to represent the regional differences in energy markets, the component models of NEMS function at regional levels appropriate for the markets represented, with subsequent aggregation/disaggregation to the Census Division level for reporting purposes.

  6. Genome-Wide Identification and 3D Modeling of Proteins involved in DNA Damage Recognition and Repair (Final Report)

    SciTech Connect (OSTI)

    Ruben A. Abagyan, PhD

    2004-04-15

    OAK-B135 DNA Damage Recognition and Repair (DDR and R) proteins play a critical role in cellular responses to low-dose radiation and are associated with cancer. the authors have performed a systematic, genome-wide computational analysis of genomic data for human genes involved in the DDR and R process. The significant achievements of this project include: (1) Construction of the computational pipeline for searching DDR and R genes, building and validation of 3D models of proteins involved in DDR and R; (2) Functional and structural annotation of the 3D models and generation of comprehensive lists of suggested knock-out mutations; (3) Important improvement of macromolecular docking technology and its application to predict the DNA-Protein complex conformation; (4) Development of a new algorithm for improved analysis of high-density oligonucleotide arrays for gene expression profiling; (5) Construction and maintenance of the DNA Damage Recognition and Repair Database; and (6) Producing 14 research papers (10 published and 4 in preparation).

  7. Genome-Wide Identification and 3D Modeling of Proteins involved in DNA Damage Recognition and Repair (Final Report)

    SciTech Connect (OSTI)

    Abagyan, Ruben; An, Jianghong

    2005-08-12

    DNA Damage Recognition and Repair (DDR&R) proteins play a critical role in cellular responses to low-dose radiation and are associated with cancer. We have performed a systematic, genome-wide computational analysis of genomic data for human genes involved in the DDR&R process. The significant achievements of this project include: 1) Construction of the computational pipeline for searching DDR&R genes, building and validation of 3D models of proteins involved in DDR&R; 2) Functional and structural annotation of the 3D models and generation of comprehensive lists of suggested knock-out mutations; and the development of a method to predict the effects of mutations. Large scale testing of technology to identify novel small binding pockets in protein structures leading to new DDRR inhibitor strategies 3) Improvements of macromolecular docking technology (see the CAPRI 1-3 and 4-5 results) 4) Development of a new algorithm for improved analysis of high-density oligonucleotide arrays for gene expression profiling; 5) Construction and maintenance of the DNA Damage Recognition and Repair Database; 6) Producing 15 research papers (12 published and 3 in preparation).

  8. Model documentation report: Industrial sector demand module of the National Energy Modeling System

    SciTech Connect (OSTI)

    NONE

    1997-01-01

    This report documents the objectives, analytical approach, and development of the National Energy Modeling System (NEMS) Industrial Demand Model. The report catalogues and describes model assumptions, computational methodology, parameter estimation techniques, and model source code. This document serves three purposes. First, it is a reference document providing a detailed description of the NEMS Industrial Model for model analysts, users, and the public. Second, this report meets the legal requirement of the Energy Information Administration (EIA) to provide adequate documentation in support of its models. Third, it facilitates continuity in model development by providing documentation from which energy analysts can undertake model enhancements, data updates, and parameter refinements as future projects. The NEMS Industrial Demand Model is a dynamic accounting model, bringing together the disparate industries and uses of energy in those industries, and putting them together in an understandable and cohesive framework. The Industrial Model generates mid-term (up to the year 2015) forecasts of industrial sector energy demand as a component of the NEMS integrated forecasting system. From the NEMS system, the Industrial Model receives fuel prices, employment data, and the value of industrial output. Based on the values of these variables, the Industrial Model passes back to the NEMS system estimates of consumption by fuel types.

  9. Parent Involvement 

    E-Print Network [OSTI]

    Howard, Jeff W.

    2005-05-10

    To be successful, a 4-H program must have parent involvement. Although 4-H leaders and Extension agents may interest young people in becoming members, they need the parents' goodwill and support to keep them interested, ...

  10. Comprehensive Electricity Competition Act: A Comparison of Model Results, The

    Reports and Publications (EIA)

    1999-01-01

    This report describes the Energy Information Administration's use of the National Energy Modeling System (NEMS) to evaluate the effects of the Administration's restructuring proposal using the parameter settings and assumptions from the Policy Office Electricity Modeling System (POEMS) analysis.

  11. A sensitivity analysis of the treatment of wind energy in the AEO99 version of NEMS

    E-Print Network [OSTI]

    Osborn, Julie G.; Wood, Frances; Richey, Cooper; Sanders, Sandy; Short, Walter; Koomey, Jonathan

    2001-01-01

    Documentation Report: Wind Energy Submodule (WES). DOE/EIA-The Economic Value of Wind Energy at High Power Systemthe characterization of wind energy in the model as used for

  12. The National Energy Modeling System: An overview

    SciTech Connect (OSTI)

    Not Available

    1994-05-01

    The National Energy Modeling System (NEMS) is a computer-based, energy-economy modeling system of US energy markets for the midterm period of 1990 to 2010. NEMS projects the production, imports, conversion, consumption, and prices of energy, subject to assumptions on macroeconomic and financial factors, world energy markets, resource availability and costs, behavioral and technological choice criteria, cost and performance characteristics of energy technologies, and demographics. This report presents an overview of the structure and methodology of NEMS and each of its components. The first chapter provides a description of the design and objectives of the system. The second chapter describes the modeling structure. The remainder of the report summarizes the methodology and scope of the component modules of NEMS. The model descriptions are intended for readers familiar with terminology from economics, operations research, and energy modeling. Additional background on the development of the system is provided in Appendix A of this report, which describes the EIA modeling systems that preceded NEMS. More detailed model documentation reports for all the NEMS modules are also available from EIA.

  13. Finding candidate genes under positive selection in Non-model species: examples of genes involved in host

    E-Print Network [OSTI]

    of positive selection were putatively involved in nutrient uptake from the host, secondary metabolite, UMR 7205, CNRS-MNHN, Origine, Structure et Evolution de la Biodiversite´, De´partement Syste and to develop vaccines or drugs. To elucidate the functions involved in host specialization, here we aimed

  14. The National Energy Modeling System: An overview 1998

    SciTech Connect (OSTI)

    1998-02-01

    The National Energy Modeling System (NEMS) is a computer-based, energy-economy modeling system of US energy markets for the midterm period through 2020. NEMS projects the production, imports, conversion, consumption, and prices of energy, subject to assumptions on macroeconomic and financial factors world energy markets, resource availability and costs, behavior and technological choice criteria, cost and performance characteristics of energy technologies, and demographics. This report presents an overview of the structure and methodology of NEMS and each of its components. The first chapter provides a description of the design and objectives of the system, followed by a chapter on the overall modeling structure and solution algorithm. The remainder of the report summarizes the methodology and scope of the component modules of NEMS. The model descriptions are intended for readers familiar with terminology from economics, operations research, and energy modeling. 21 figs.

  15. Finding Common Ground: Exploring the Experiences of Client Involvement in Medication Decisions Using a Shared Decision Making Model

    E-Print Network [OSTI]

    Goscha, Richard J.

    2009-12-01

    medications. Purposeful sampling, with an emphasis on achieving maximum variation, was used to better understand the interactive processes that contribute to as well as hinder client involvement in shared decision making. Multiple interviews with all...

  16. Net Energy Metering (NEM)

    Broader source: Energy.gov (indexed) [DOE]

    facilities on the military installation does not exceed 50% of the highest daily peak demand for electricity at that military installation over the course of the preceding...

  17. NEMS International Energy Module

    U.S. Energy Information Administration (EIA) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home PageMonthly","10/2015"4,"Ames5 Tables July 1996 Energy Information Administration Office of Coal, Nuclear,Decade Year-03.82 (MillionandIndustrialYear137

  18. Model documentation report: Industrial sector demand module of the national energy modeling system

    SciTech Connect (OSTI)

    NONE

    1998-01-01

    This report documents the objectives, analytical approach, and development of the National Energy Modeling System (NEMS) Industrial Demand Model. The report catalogues and describes model assumptions, computational methodology, parameter estimation techniques, and model source code. This document serves three purposes. First, it is a reference document providing a detailed description of the NEMS Industrial Model for model analysts, users, and the public. Second, this report meets the legal requirements of the Energy Information Administration (EIA) to provide adequate documentation in support of its model. Third, it facilitates continuity in model development by providing documentation from which energy analysts can undertake model enhancements, data updates, and parameter refinements as future projects.

  19. Impacts of Modeled Recommendations of the National Commission on Energy Policy

    Reports and Publications (EIA)

    2005-01-01

    This report provides the Energy Information Administration's analysis of those National Commission on Energy Policy (NCEP) energy policy recommendations that could be simulated using the National Energy Modeling System (NEMS).

  20. Model documentation, Coal Market Module of the National Energy Modeling System

    SciTech Connect (OSTI)

    NONE

    1998-01-01

    This report documents the objectives and the conceptual and methodological approach used in the development of the National Energy Modeling System`s (NEMS) Coal Market Module (CMM) used to develop the Annual Energy Outlook 1998 (AEO98). This report catalogues and describes the assumptions, methodology, estimation techniques, and source code of CMM`s two submodules. These are the Coal Production Submodule (CPS) and the Coal Distribution Submodule (CDS). CMM provides annual forecasts of prices, production, and consumption of coal for NEMS. In general, the CDS integrates the supply inputs from the CPS to satisfy demands for coal from exogenous demand models. The international area of the CDS forecasts annual world coal trade flows from major supply to major demand regions and provides annual forecasts of US coal exports for input to NEMS. Specifically, the CDS receives minemouth prices produced by the CPS, demand and other exogenous inputs from other NEMS components, and provides delivered coal prices and quantities to the NEMS economic sectors and regions.

  1. Model documentation: Natural gas transmission and distribution model of the National Energy Modeling System. Volume 1

    SciTech Connect (OSTI)

    1995-02-17

    The Natural Gas Transmission and Distribution Model (NGTDM) is the component of the National Energy Modeling System (NEMS) that is used to represent the domestic natural gas transmission and distribution system. NEMS was developed in the Office of integrated Analysis and Forecasting of the Energy information Administration (EIA). NEMS is the third in a series of computer-based, midterm energy modeling systems used since 1974 by the EIA and its predecessor, the Federal Energy Administration, to analyze domestic energy-economy markets and develop projections. The NGTDM is the model within the NEMS that represents the transmission, distribution, and pricing of natural gas. The model also includes representations of the end-use demand for natural gas, the production of domestic natural gas, and the availability of natural gas traded on the international market based on information received from other NEMS models. The NGTDM determines the flow of natural gas in an aggregate, domestic pipeline network, connecting domestic and foreign supply regions with 12 demand regions. The methodology employed allows the analysis of impacts of regional capacity constraints in the interstate natural gas pipeline network and the identification of pipeline capacity expansion requirements. There is an explicit representation of core and noncore markets for natural gas transmission and distribution services, and the key components of pipeline tariffs are represented in a pricing algorithm. Natural gas pricing and flow patterns are derived by obtaining a market equilibrium across the three main elements of the natural gas market: the supply element, the demand element, and the transmission and distribution network that links them. The NGTDM consists of four modules: the Annual Flow Module, the Capacity F-expansion Module, the Pipeline Tariff Module, and the Distributor Tariff Module. A model abstract is provided in Appendix A.

  2. Natural Gas Transmission and Distribution Model of the National Energy Modeling System. Volume 1

    SciTech Connect (OSTI)

    1998-01-01

    The Natural Gas Transmission and Distribution Model (NGTDM) is the component of the National Energy Modeling System (NEMS) that is used to represent the domestic natural gas transmission and distribution system. The NGTDM is the model within the NEMS that represents the transmission, distribution, and pricing of natural gas. The model also includes representations of the end-use demand for natural gas, the production of domestic natural gas, and the availability of natural gas traded on the international market based on information received from other NEMS models. The NGTDM determines the flow of natural gas in an aggregate, domestic pipeline network, connecting domestic and foreign supply regions with 12 demand regions. The purpose of this report is to provide a reference document for model analysts, users, and the public that defines the objectives of the model, describes its basic design, provides detail on the methodology employed, and describes the model inputs, outputs, and key assumptions. Subsequent chapters of this report provide: an overview of NGTDM; a description of the interface between the NEMS and NGTDM; an overview of the solution methodology of the NGTDM; the solution methodology for the Annual Flow Module; the solution methodology for the Distributor Tariff Module; the solution methodology for the Capacity Expansion Module; the solution methodology for the Pipeline Tariff Module; and a description of model assumptions, inputs, and outputs.

  3. Understanding Energy Models and Modeling (ENV 715) Spring 2013 Tuesday/Thursday 10:05-11:20 am

    E-Print Network [OSTI]

    Ferrari, Silvia

    topics for Congress, and publishes the Annual Energy Outlook. At Duke, NI-NEMS has recently been used1 Understanding Energy Models and Modeling (ENV 715) Spring 2013 Tuesday/Thursday 10:05-11:20 am) Course Description and Learning Objectives Energy models are widely used for policy analysis, scenario

  4. Directory of energy information administration models 1995

    SciTech Connect (OSTI)

    1995-07-13

    This updated directory has been published annually; after this issue, it will be published only biennially. The Disruption Impact Simulator Model in use by EIA is included. Model descriptions have been updated according to revised documentation approved during the past year. This directory contains descriptions about each model, including title, acronym, purpose, followed by more detailed information on characteristics, uses, and requirements. Sources for additional information are identified. Included are 37 EIA models active as of February 1, 1995. The first group is the National Energy Modeling System (NEMS) models. The second group is all other EIA models that are not part of NEMS. Appendix A identifies major EIA modeling systems and the models within these systems. Appendix B is a summary of the `Annual Energy Outlook` Forecasting System.

  5. Model documentation Coal Market Module of the National Energy Modeling System

    SciTech Connect (OSTI)

    NONE

    1996-04-30

    This report documents objectives and conceptual and methodological approach used in the development of the National Energy Modeling System (NEMS) Coal Market Module (CMM) used to develop the Annual Energy Outlook 1996 (AEO96). This report catalogues and describes the assumptions, methodology, estimation techniques, and source code of CMM`s three submodules: Coal Production Submodule, Coal Export Submodule, and Coal Distribution Submodule.

  6. Data gathering to build and validate small-scale social models for simulation. Two ways: strict control and stake-holders involvement

    E-Print Network [OSTI]

    Tesfatsion, Leigh

    Data gathering to build and validate small-scale social models for simulation. Two ways: strict. Nowadays, it has become a norm to assess results with actually comparable data and to build the hypothesis for the right use of empirical data in the building of models (Moss and Edmonds, 2005). In this paper, we focus

  7. A Model of U.S. Commercial Distributed Generation Adoption

    SciTech Connect (OSTI)

    LaCommare, Kristina Hamachi; Ryan Firestone; Zhou, Nan; Maribu,Karl; Marnay, Chris

    2006-01-10

    Small-scale (100 kW-5 MW) on-site distributed generation (DG) economically driven by combined heat and power (CHP) applications and, in some cases, reliability concerns will likely emerge as a common feature of commercial building energy systems over the next two decades. Forecasts of DG adoption published by the Energy Information Administration (EIA) in the Annual Energy Outlook (AEO) are made using the National Energy Modeling System (NEMS), which has a forecasting module that predicts the penetration of several possible commercial building DG technologies over the period 2005-2025. NEMS is also used for estimating the future benefits of Department of Energy research and development used in support of budget requests and management decisionmaking. The NEMS approach to modeling DG has some limitations, including constraints on the amount of DG allowed for retrofits to existing buildings and a small number of possible sizes for each DG technology. An alternative approach called Commercial Sector Model (ComSeM) is developed to improve the way in which DG adoption is modeled. The approach incorporates load shapes for specific end uses in specific building types in specific regions, e.g., cooling in hospitals in Atlanta or space heating in Chicago offices. The Distributed Energy Resources Customer Adoption Model (DER-CAM) uses these load profiles together with input cost and performance DG technology assumptions to model the potential DG adoption for four selected cities and two sizes of five building types in selected forecast years to 2022. The Distributed Energy Resources Market Diffusion Model (DER-MaDiM) is then used to then tailor the DER-CAM results to adoption projections for the entire U.S. commercial sector for all forecast years from 2007-2025. This process is conducted such that the structure of results are consistent with the structure of NEMS, and can be re-injected into NEMS that can then be used to integrate adoption results into a full forecast.

  8. Model documentation report: Commercial Sector Demand Module of the National Energy Modeling System

    SciTech Connect (OSTI)

    1998-01-01

    This report documents the objectives, analytical approach and development of the National Energy Modeling System (NEMS) Commercial Sector Demand Module. The report catalogues and describes the model assumptions, computational methodology, parameter estimation techniques, model source code, and forecast results generated through the synthesis and scenario development based on these components. The NEMS Commercial Sector Demand Module is a simulation tool based upon economic and engineering relationships that models commercial sector energy demands at the nine Census Division level of detail for eleven distinct categories of commercial buildings. Commercial equipment selections are performed for the major fuels of electricity, natural gas, and distillate fuel, for the major services of space heating, space cooling, water heating, ventilation, cooking, refrigeration, and lighting. The algorithm also models demand for the minor fuels of residual oil, liquefied petroleum gas, steam coal, motor gasoline, and kerosene, the renewable fuel sources of wood and municipal solid waste, and the minor services of office equipment. Section 2 of this report discusses the purpose of the model, detailing its objectives, primary input and output quantities, and the relationship of the Commercial Module to the other modules of the NEMS system. Section 3 of the report describes the rationale behind the model design, providing insights into further assumptions utilized in the model development process to this point. Section 3 also reviews alternative commercial sector modeling methodologies drawn from existing literature, providing a comparison to the chosen approach. Section 4 details the model structure, using graphics and text to illustrate model flows and key computations.

  9. Diallylsulfide attenuates excessive collagen production and apoptosis in a rat model of bleomycin induced pulmonary fibrosis through the involvement of protease activated receptor-2

    SciTech Connect (OSTI)

    Kalayarasan, Srinivasan, E-mail: kalaivasanbio@gmail.com; Sriram, Narayanan; Soumyakrishnan, Syamala; Sudhandiran, Ganapasam, E-mail: sudhandiran@yahoo.com

    2013-09-01

    Pulmonary fibrosis (PF) can be a devastating lung disease. It is primarily caused by inflammation leading to severe damage of the alveolar epithelial cells. The pathophysiology of PF is not yet been clearly defined, but studying lung parenchymal injury by involving reactive oxygen species (ROS) through the activation of protease activated receptor-2 (PAR-2) may provide promising results. PAR-2 is a G-protein coupled receptor is known to play an important role in the development of PF. In this study, we investigated the inhibitory role of diallylsulfide (DAS) against ROS mediated activation of PAR-2 and collagen production accompanied by epithelial cell apoptosis. Bleomycin induced ROS levels may prompt to induce the expression of PAR-2 as well as extracellular matrix proteins (ECM), such as MMP 2 and 9, collagen specific proteins HSP-47, ?-SMA, and cytokines IL-6, and IL-8RA. Importantly DAS treatment effectively decreased the expression of all these proteins. The inhibitory effect of DAS on profibrotic molecules is mediated by blocking the ROS level. To identify apoptotic signaling as a mediator of PF induction, we performed apoptotic protein expression, DNA fragmentation analysis and ultrastructural details of the lung tissue were performed. DAS treatment restored all these changes to near normalcy. In conclusion, treatment of PF bearing rats with DAS results in amelioration of the ROS production, PAR-2 activation, ECM production, collagen synthesis and alveolar epithelial cell apoptosis during bleomycin induction. We attained the first evidence that treatment of DAS decreases the ROS levels and may provide a potential therapeutic effect attenuating bleomycin induced PF. - Highlights: • DAS inhibits PAR-2 activity; bleomycin stimulates PAR-2 activity. • Increase in PAR-2 activity is correlated with pulmonary fibrosis • DAS reduces pro-inflammatory activity linked to facilitating pulmonary fibrosis. • DAS inhibits apoptosis of alveolar epithelial cells.

  10. Model documentation report: Macroeconomic Activity Module (MAM) of the National Energy Modeling System

    SciTech Connect (OSTI)

    NONE

    1997-02-01

    This report documents the objectives, analytical approach, and development of the National Energy Modeling System (NEMS) Macroeconomic Activity Module (MAM) used to develop the Annual Energy Outlook for 1997 (AEO 97). The report catalogues and describes the module assumptions, computations, methodology, parameter estimation techniques, and mainframe source code. This document serves three purposes. First it is a reference document providing a detailed description of the NEMS MAM used for the AEO 1997 production runs for model analysts, users, and the public. Second, this report meets the legal requirement of the Energy Information Administration (EIA) to provide adequate documentation in support of its models. Third, it facilitates continuity in model development by providing documentation from which energy analysts can undertake model enhancements, data updates, and parameter refinements as future projects.

  11. Directory of Energy Information Administration Models 1994

    SciTech Connect (OSTI)

    Not Available

    1994-07-01

    This directory revises and updates the 1993 directory and includes 15 models of the National Energy Modeling System (NEMS). Three other new models in use by the Energy Information Administration (EIA) have also been included: the Motor Gasoline Market Model (MGMM), Distillate Market Model (DMM), and the Propane Market Model (PPMM). This directory contains descriptions about each model, including title, acronym, purpose, followed by more detailed information on characteristics, uses and requirements. Sources for additional information are identified. Included in this directory are 37 EIA models active as of February 1, 1994.

  12. Model documentation: Natural Gas Transmission and Distribution Model of the National Energy Modeling System; Volume 1

    SciTech Connect (OSTI)

    1994-02-24

    The Natural Gas Transmission and Distribution Model (NGTDM) is a component of the National Energy Modeling System (NEMS) used to represent the domestic natural gas transmission and distribution system. NEMS is the third in a series of computer-based, midterm energy modeling systems used since 1974 by the Energy Information Administration (EIA) and its predecessor, the Federal Energy Administration, to analyze domestic energy-economy markets and develop projections. This report documents the archived version of NGTDM that was used to produce the natural gas forecasts used in support of the Annual Energy Outlook 1994, DOE/EIA-0383(94). The purpose of this report is to provide a reference document for model analysts, users, and the public that defines the objectives of the model, describes its basic design, provides detail on the methodology employed, and describes the model inputs, outputs, and key assumptions. It is intended to fulfill the legal obligation of the EIA to provide adequate documentation in support of its models (Public Law 94-385, Section 57.b.2). This report represents Volume 1 of a two-volume set. (Volume 2 will report on model performance, detailing convergence criteria and properties, results of sensitivity testing, comparison of model outputs with the literature and/or other model results, and major unresolved issues.) Subsequent chapters of this report provide: (1) an overview of the NGTDM (Chapter 2); (2) a description of the interface between the National Energy Modeling System (NEMS) and the NGTDM (Chapter 3); (3) an overview of the solution methodology of the NGTDM (Chapter 4); (4) the solution methodology for the Annual Flow Module (Chapter 5); (5) the solution methodology for the Distributor Tariff Module (Chapter 6); (6) the solution methodology for the Capacity Expansion Module (Chapter 7); (7) the solution methodology for the Pipeline Tariff Module (Chapter 8); and (8) a description of model assumptions, inputs, and outputs (Chapter 9).

  13. Model documentation: Renewable Fuels Module of the National Energy Modeling System

    SciTech Connect (OSTI)

    Not Available

    1994-04-01

    This report documents the objectives, analytical approach, and design of the National Energy Modeling System (NEMS) Renewable Fuels Module (RFM) as it related to the production of the 1994 Annual Energy Outlook (AEO94) forecasts. The report catalogues and describes modeling assumptions, computational methodologies, data inputs, and parameter estimation techniques. A number of offline analyses used in lieu of RFM modeling components are also described. This documentation report serves two purposes. First, it is a reference document for model analysts, model users, and the public interested in the construction and application of the RFM. Second, it meets the legal requirement of the Energy Information Administration (EIA) to provide adequate documentation in support of its models. The RFM consists of six analytical submodules that represent each of the major renewable energy resources -- wood, municipal solid waste (MSW), solar energy, wind energy, geothermal energy, and alcohol fuels. Of these six, four are documented in the following chapters: municipal solid waste, wind, solar and biofuels. Geothermal and wood are not currently working components of NEMS. The purpose of the RFM is to define the technological and cost characteristics of renewable energy technologies, and to pass these characteristics to other NEMS modules for the determination of mid-term forecasted renewable energy demand.

  14. MODELING THE DEMAND FOR E85 IN THE UNITED STATES

    SciTech Connect (OSTI)

    Liu, Changzheng; Greene, David L

    2013-10-01

    How demand for E85 might evolve in the future in response to changing economics and policies is an important subject to include in the National Energy Modeling System (NEMS). This report summarizes a study to develop an E85 choice model for NEMS. Using the most recent data from the states of Minnesota, North Dakota, and Iowa, this study estimates a logit model that represents E85 choice as a function of prices of E10 and E85, as well as fuel availability of E85 relative to gasoline. Using more recent data than previous studies allows a better estimation of non-fleet demand and indicates that the price elasticity of E85 choice appears to be higher than previously estimated. Based on the results of the econometric analysis, a model for projecting E85 demand at the regional level is specified. In testing, the model produced plausible predictions of US E85 demand to 2040.

  15. Multiscale treatment of mechanical contact problems involving thin polymeric layers

    E-Print Network [OSTI]

    ) and nanoelectromechanical (NEMS) systems for industrial applications [1]. This field is concerned with the study of energy wasted because of friction, which occurs in particular between mechanical components such as gears and bearings. Hence it greatly influences the design of devices containing moving parts, like motors and hard

  16. Policy on Programs Involving Minors Policy on Programs Involving

    E-Print Network [OSTI]

    Sridhar, Srinivas

    Policy on Programs Involving Minors 6/4/2014 Policy on Programs Involving Minors I. Purpose in University-sponsored activities that take place off campus. This policy applies to University or facilities that are operated or sponsored by third parties. This policy provides program registration

  17. RESEARCH OR TEACHING INVOLVING ANIMALS

    E-Print Network [OSTI]

    Victoria, University of

    Page 1 RESEARCH OR TEACHING INVOLVING ANIMALS University Policy No: RH8110 Classification: Research Approving Authority: Vice-President Research Effective date: June, 2014 Supersedes: December, 2010 Last for Conducting Research or Teaching Involving Animals Animal Care Committee Terms of Reference PURPOSE 1

  18. Modeling Interregional Transmission Congestion in the National Energy Modeling System

    E-Print Network [OSTI]

    Gumerman, Etan; Chan, Peter; Lesieutre, Bernard; Marnay, Chris; Wang, Juan

    2006-01-01

    Central Area Reliability Coordination Council EMM region Electricity Capacity Planning submodule of NEMS Energy Efficiency and Renewable

  19. Some Ramsey Problems Involving Triangles -

    E-Print Network [OSTI]

    Radziszowski, Stanislaw P.

    Some Ramsey Problems Involving Triangles - Computational Approach Stanislaw Pawel Radziszowski Department of Computer Science Rochester Institute of Technology, NY ramsey@dimacs, 28 may 2009 1/40 #12;Outline - Triangles Everywhere or avoiding K3 in some/most colors 1 Ramsey Numbers - Two Colors Some known

  20. Radiological science involves technologists use

    E-Print Network [OSTI]

    Sibille, Etienne

    English Composition II Mathematics MATH 0110 Fundamentals of Mathematics THE HUMAN EXPERIENCE Students new Clinical Experience Radiographic Procedures II Radiation Protection II Radiographic Film ProcessingRadiological science involves technologists use X-rays to see the inside of the human body. Health

  1. Transportation Sector Model of the National Energy Modeling System. Volume 1

    SciTech Connect (OSTI)

    1998-01-01

    This report documents the objectives, analytical approach and development of the National Energy Modeling System (NEMS) Transportation Model (TRAN). The report catalogues and describes the model assumptions, computational methodology, parameter estimation techniques, model source code, and forecast results generated by the model. The NEMS Transportation Model comprises a series of semi-independent models which address different aspects of the transportation sector. The primary purpose of this model is to provide mid-term forecasts of transportation energy demand by fuel type including, but not limited to, motor gasoline, distillate, jet fuel, and alternative fuels (such as CNG) not commonly associated with transportation. The current NEMS forecast horizon extends to the year 2010 and uses 1990 as the base year. Forecasts are generated through the separate consideration of energy consumption within the various modes of transport, including: private and fleet light-duty vehicles; aircraft; marine, rail, and truck freight; and various modes with minor overall impacts, such as mass transit and recreational boating. This approach is useful in assessing the impacts of policy initiatives, legislative mandates which affect individual modes of travel, and technological developments. The model also provides forecasts of selected intermediate values which are generated in order to determine energy consumption. These elements include estimates of passenger travel demand by automobile, air, or mass transit; estimates of the efficiency with which that demand is met; projections of vehicle stocks and the penetration of new technologies; and estimates of the demand for freight transport which are linked to forecasts of industrial output. Following the estimation of energy demand, TRAN produces forecasts of vehicular emissions of the following pollutants by source: oxides of sulfur, oxides of nitrogen, total carbon, carbon dioxide, carbon monoxide, and volatile organic compounds.

  2. Model documentation report: Transportation sector model of the National Energy Modeling System

    SciTech Connect (OSTI)

    Not Available

    1994-03-01

    This report documents the objectives, analytical approach and development of the National Energy Modeling System (NEMS) Transportation Model (TRAN). The report catalogues and describes the model assumptions, computational methodology, parameter estimation techniques, model source code, and forecast results generated by the model. This document serves three purposes. First, it is a reference document providing a detailed description of TRAN for model analysts, users, and the public. Second, this report meets the legal requirements of the Energy Information Administration (EIA) to provide adequate documentation in support of its statistical and forecast reports (Public Law 93-275, 57(b)(1)). Third, it permits continuity in model development by providing documentation from which energy analysts can undertake model enhancements, data updates, and parameter refinements.

  3. Modeling renewable portfolio standards for the annual energy outlook 1998 - electricity market module

    SciTech Connect (OSTI)

    NONE

    1998-02-01

    The Electricity Market Module (EMM) is the electricity supply component of the National Energy Modeling System (NEMS). The EMM represents the generation, transmission, and pricing of electricity. It consists of four submodules: the Electricity Capacity Planning (ECP) Submodule, the Electricity Fuel Dispatch (EFD) Submodule, the Electricity Finance and Pricing (EFP) Submodule, and the Load and Demand-Side Management (LDSM) Submodule. For the Annual Energy Outlook 1998 (AEO98), the EMM has been modified to represent Renewable Portfolio Standards (RPS), which are included in many of the Federal and state proposals for deregulating the electric power industry. A RPS specifies that electricity suppliers must produce a minimum level of generation using renewable technologies. Producers with insufficient renewable generating capacity can either build new plants or purchase {open_quotes}credits{close_quotes} from other suppliers with excess renewable generation. The representation of a RPS involves revisions to the ECP, EFD, and the EFP. The ECP projects capacity additions required to meet the minimum renewable generation levels in future years. The EFD determines the sales and purchases of renewable credits for the current year. The EFP incorporates the cost of building capacity and trading credits into the price of electricity.

  4. Summary Impacts of Modeled Provisions of the 2003 Conference Energy Bill

    Reports and Publications (EIA)

    2004-01-01

    This service report was undertaken at the February 2, 2004, request of Senator John Sununu to perform an assessment of the Conference Energy Bill of 2003. This report summarizes the CEB provisions that can be analyzed using the National Energy Modeling System (NEMS) and have the potential to affect energy consumption, supply, and prices. The impacts are estimated by comparing the projections with the CEB provisions to the AEO2004 Reference Case.

  5. On an integral involving the digamma function

    E-Print Network [OSTI]

    Donal F. Connon

    2012-12-09

    We consider several possible approaches to evaluating an integral involving the digamma function and a related logarithmic series.

  6. Modeling Interregional Transmission Congestion in the National Energy Modeling System

    E-Print Network [OSTI]

    Gumerman, Etan; Chan, Peter; Lesieutre, Bernard; Marnay, Chris; Wang, Juan

    2006-01-01

    NEMS does not track electricity transmission within regions,international electricity transmission with Canada andwhen solving for electricity transmission, the coal plants

  7. Cyber Incidents Involving Control Systems

    SciTech Connect (OSTI)

    Robert J. Turk

    2005-10-01

    The Analysis Function of the US-CERT Control Systems Security Center (CSSC) at the Idaho National Laboratory (INL) has prepared this report to document cyber security incidents for use by the CSSC. The description and analysis of incidents reported herein support three CSSC tasks: establishing a business case; increasing security awareness and private and corporate participation related to enhanced cyber security of control systems; and providing informational material to support model development and prioritize activities for CSSC. The stated mission of CSSC is to reduce vulnerability of critical infrastructure to cyber attack on control systems. As stated in the Incident Management Tool Requirements (August 2005) ''Vulnerability reduction is promoted by risk analysis that tracks actual risk, emphasizes high risk, determines risk reduction as a function of countermeasures, tracks increase of risk due to external influence, and measures success of the vulnerability reduction program''. Process control and Supervisory Control and Data Acquisition (SCADA) systems, with their reliance on proprietary networks and hardware, have long been considered immune to the network attacks that have wreaked so much havoc on corporate information systems. New research indicates this confidence is misplaced--the move to open standards such as Ethernet, Transmission Control Protocol/Internet Protocol, and Web technologies is allowing hackers to take advantage of the control industry's unawareness. Much of the available information about cyber incidents represents a characterization as opposed to an analysis of events. The lack of good analyses reflects an overall weakness in reporting requirements as well as the fact that to date there have been very few serious cyber attacks on control systems. Most companies prefer not to share cyber attack incident data because of potential financial repercussions. Uniform reporting requirements will do much to make this information available to Department of Homeland Security (DHS) and others who require it. This report summarizes the rise in frequency of cyber attacks, describes the perpetrators, and identifies the means of attack. This type of analysis, when used in conjunction with vulnerability analyses, can be used to support a proactive approach to prevent cyber attacks. CSSC will use this document to evolve a standardized approach to incident reporting and analysis. This document will be updated as needed to record additional event analyses and insights regarding incident reporting. This report represents 120 cyber security incidents documented in a number of sources, including: the British Columbia Institute of Technology (BCIT) Industrial Security Incident Database, the 2003 CSI/FBI Computer Crime and Security Survey, the KEMA, Inc., Database, Lawrence Livermore National Laboratory, the Energy Incident Database, the INL Cyber Incident Database, and other open-source data. The National Memorial Institute for the Prevention of Terrorism (MIPT) database was also interrogated but, interestingly, failed to yield any cyber attack incidents. The results of this evaluation indicate that historical evidence provides insight into control system related incidents or failures; however, that the limited available information provides little support to future risk estimates. The documented case history shows that activity has increased significantly since 1988. The majority of incidents come from the Internet by way of opportunistic viruses, Trojans, and worms, but a surprisingly large number are directed acts of sabotage. A substantial number of confirmed, unconfirmed, and potential events that directly or potentially impact control systems worldwide are also identified. Twelve selected cyber incidents are presented at the end of this report as examples of the documented case studies (see Appendix B).

  8. Model documentation report: Commercial Sector Demand Module of the National Energy Modeling System

    SciTech Connect (OSTI)

    NONE

    1995-02-01

    This report documents the objectives, analytical approach and development of the National Energy Modeling System (NEMS) Commercial Sector Demand Module. The report catalogues and describes the model assumptions, computational methodology, parameter estimation techniques, model source code, and forecast results generated through the synthesis and scenario development based on these components. This report serves three purposes. First, it is a reference document providing a detailed description for model analysts, users, and the public. Second, this report meets the legal requirement of the Energy Information Administration (EIA) to provide adequate documentation in support of its statistical and forecast reports (Public Law 93-275, section 57(b)(1)). Third, it facilitates continuity in model development by providing documentation from which energy analysts can undertake model enhancements, data updates, and parameter refinements as future projects.

  9. Ramsey Numbers Involving Cycles Stanislaw P. Radziszowski

    E-Print Network [OSTI]

    Radziszowski, Stanislaw P.

    Ramsey Numbers Involving Cycles Stanislaw P. Radziszowski Department of Computer Science Rochester and data on Ramsey numbers involving cycles. This survey is based on the author's 2009 revi- sion #12 of the Dynamic Survey DS1, "Small Ramsey Numbers", at the Electronic Journal of Combinatorics. Table of Contents

  10. RESEARCH INVOLVING PRISONERS DEFINITIONS AND EXAMPLES

    E-Print Network [OSTI]

    1 RESEARCH INVOLVING PRISONERS 05/30/2008 DEFINITIONS AND EXAMPLES The DUHS IRB reviews and approves research involving prisoners in compliance with 45 CFR 46 Subpart C and other applicable regulations and laws. The provisions of Subpart C apply whenever the research targets prisoners as subjects

  11. Prefrontal involvement in the regulation of emotion: convergence of rat and human studies

    E-Print Network [OSTI]

    Quirk, Gregory J.

    experiments designed to bridge human and rodent models of emotion regulation. Addresses 1 Department of prefrontal involvement of emotion regula- tion using rat and human models, and suggest future experimentsPrefrontal involvement in the regulation of emotion: convergence of rat and human studies Gregory J

  12. Ethnic differences in parent involvement are moderated by type of involvement scale 

    E-Print Network [OSTI]

    Wong, Shuk Wa

    2006-10-30

    This study examines ethnic group differences on different dimensions of parentrated and teacher-rated parent involvement after adjusting for the influence of family socioeconomic factors, and the role of involvement scale ...

  13. Bounds on Some Ramsey Numbers Involving Quadrilateral +

    E-Print Network [OSTI]

    Radziszowski, Stanislaw P.

    Bounds on Some Ramsey Numbers Involving Quadrilateral + Xiaodong Xu Guangxi Academy of Sciences@cs.rit.edu Abstract. For graphs G 1 , G 2 , · · · , Gm , the Ramsey number R(G 1 , G 2 , · · · , Gm ) is defined Ramsey numbers involving quadrilateral C 4 , including R(C 4 , K 9 ) # 32, 19 # R(C 4 , C 4 , K 4 ) # 22

  14. Physical Models of Noncovalent Interactions Involving Aromatic Rings 

    E-Print Network [OSTI]

    Bloom, Jacob Walter Goldstein

    2014-04-17

    is expanded to the use of electric fields to reconcile unusual similarity in the substituent effects between benzene, triazine, and borazine. Substituent effects for different rings are similar as long as the electric fields of those rings are similar...

  15. Numerical modelling of flows involving submerged bodies and free surfaces 

    E-Print Network [OSTI]

    Topper, Mathew Bernard Robert

    2011-06-28

    Kinetic energy extraction devices for ocean and river flows are often located in the vicinity of the fluid free surface. This differs from wind turbines where the atmosphere may be considered to extend to infinity for ...

  16. Model documentation report: Residential sector demand module of the National Energy Modeling System

    SciTech Connect (OSTI)

    1997-01-01

    This report documents the objectives, analytical approach, and development of the National Energy Modeling System (NEMS) Residential Sector Demand Module. The report catalogues and describes the model assumptions, computational methodology, parameter estimation techniques, and FORTRAN source code. This document serves three purposes. First, it is a reference document that provides a detailed description for energy analysts, other users, and the public. Second, this report meets the legal requirement of the Energy Information Administration (EIA) to provide adequate documentation in support of its statistical and forecast reports according to Public Law 93-275, section 57(b)(1). Third, it facilitates continuity in model development by providing documentation from which energy analysts can undertake model enhancements, data updates, and parameter refinements.

  17. Some Ramsey Problems Involving Triangles -Computational Approach

    E-Print Network [OSTI]

    Radziszowski, Stanislaw P.

    Some Ramsey Problems Involving Triangles - Computational Approach Stanislaw P. Radziszowski at the Ramsey Theory Workshop DIMACS, Rutgers University, May 28, 2009 Definition 1. For graphs G and H, R(G, H graphs, and the multicolor Ramsey numbers R(G1, · · · , Gr). Computational problems for Ramsey numbers

  18. Fire Classifications Fires involving the ordinary

    E-Print Network [OSTI]

    Jia, Songtao

    , plastics, etc. Fires involving combustible or flammable liquids such as gasoline, kerosene, oils, grease to prevent fires. Personnel should neither create nor tolerate conditions that could cause or fuel a fire is protected by various devices such as smoke detectors, sprinkler systems, and manual fire alarm pull stations

  19. Environmental science and ecology involve studies

    E-Print Network [OSTI]

    Christensen, Dan

    Environmental science and ecology involve studies of the biosphere, hydro- sphere, and lithosphere in environmental science is conducted on spatial scales varying from a single algal cell to the Earth as a whole's environmental scientists require investigation by an interdisciplinary team, including members from several

  20. Physical mechanisms involved in grooved flat heat pipes: experimental and numerical analyses

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    1 Physical mechanisms involved in grooved flat heat pipes: experimental and numerical analyses.lefevre@insa-lyon.fr) Abstract An experimental database, obtained with flat plate heat pipes (FPHP) with longitudinal grooves to results of numerical models. Physical mechanisms involved in grooved heat pipes are discussed, including

  1. Model documentation: Electricity market module, electricity finance and pricing submodule

    SciTech Connect (OSTI)

    Not Available

    1994-04-07

    The purpose of this report is to define the objectives of the model, describe its basic approach, and provide detail on how it works. The EFP is a regulatory accounting model that projects electricity prices. The model first solves for revenue requirements by building up a rate base, calculating a return on rate base, and adding the allowed expenses. Average revenues (prices) are calculated based on assumptions regarding regulator lag and customer cost allocation methods. The model then solves for the internal cash flow and analyzes the need for external financing to meet necessary capital expenditures. Finally, the EFP builds up the financial statements. The EFP is used in conjunction with the National Energy Modeling System (NEMS). Inputs to the EFP include the forecast generating capacity expansion plans, operating costs, regulator environment, and financial data. The outputs include forecasts of income statements, balance sheets, revenue requirements, and electricity prices.

  2. Undergraduate business and management students’ experiences of being involved in assessment 

    E-Print Network [OSTI]

    Tai, Chunming

    2012-11-29

    This study aimed to explore university undergraduates’ experiences of student involvement in assessment (SIA). Based on Biggs’ 3P model of student learning, this study focused on students’ experiences prior to SIA, during ...

  3. Apolipoprotein gene involved in lipid metabolism

    DOE Patents [OSTI]

    Rubin, Edward (Berkeley, CA); Pennacchio, Len A. (Sebastopol, CA)

    2007-07-03

    Methods and materials for studying the effects of a newly identified human gene, APOAV, and the corresponding mouse gene apoAV. The sequences of the genes are given, and transgenic animals which either contain the gene or have the endogenous gene knocked out are described. In addition, single nucleotide polymorphisms (SNPs) in the gene are described and characterized. It is demonstrated that certain SNPs are associated with diseases involving lipids and triglycerides and other metabolic diseases. These SNPs may be used alone or with SNPs from other genes to study individual risk factors. Methods for intervention in lipid diseases, including the screening of drugs to treat lipid-related or diabetic diseases are also disclosed.

  4. Modeling Interregional Transmission Congestion in the National Energy Modeling System

    E-Print Network [OSTI]

    Gumerman, Etan; Chan, Peter; Lesieutre, Bernard; Marnay, Chris; Wang, Juan

    2006-01-01

    Total Number of New Plants Generating Capacity 7.2 GW 15.7that NEMS builds for generating plants, which are dedicatedOnly certain types of generating plants can be built off the

  5. The involvement of recurrent connections in area CA3 in establishing the properties of place elds

    E-Print Network [OSTI]

    Dayan, Peter

    The involvement of recurrent connections in area CA3 in establishing the properties of place #12 model of CA3 place #12;elds 51 text pages, 12 #12;gures, 1 table 206 words in abstract, 474- tions. We describe an attractor network model of area CA3 in which local, recurrent, excitatory

  6. Frequency stabilization in nonlinear MEMS and NEMS oscillators

    DOE Patents [OSTI]

    Lopez, Omar Daniel; Antonio, Dario

    2014-09-16

    An illustrative system includes an amplifier operably connected to a phase shifter. The amplifier is configured to amplify a voltage from an oscillator. The phase shifter is operably connected to a driving amplitude control, wherein the phase shifter is configured to phase shift the amplified voltage and is configured to set an amplitude of the phase shifted voltage. The oscillator is operably connected to the driving amplitude control. The phase shifted voltage drives the oscillator. The oscillator is at an internal resonance condition, based at least on the amplitude of the phase shifted voltage, that stabilizes frequency oscillations in the oscillator.

  7. NEMS Freight Transportation Module Improvement Study - Energy Information

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustments (Billion Cubic Feet) Wyoming963Residential2, 2014ProvedYear Jan Feb Mar AprCubic

  8. Appendix C: Map of NEMS Electricity Market Module Regions

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustments (Billion Cubic Feet)Decade Year-0ProvedDecade2,948 2,724 2,570Month PreviousDry4,645 8244420 U.S.

  9. Energy Information Administration NEMS Macroeconomic Activity Module Documentation Report

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustments (Billion Cubic Feet)DecadeYear Jan Feb Mar Apr May Jun2003 Detailed Tablesof1998 and 2002

  10. Frequency Stabilization in Nonlinear MEMS and NEMS Oscillators | Argonne

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverse (Journal Article)Forthcoming Upgrades toFreezing a Droplet to Stop-

  11. Analysis and Representation of Miscellaneous Electric Loads in NEMS -

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of Natural GasAdjustments (Billion Cubic Feet) Wyoming Dry NaturalPrices1 Table 1.10 CoolingNotesShaleOil andEnergy Information

  12. Genomic Aspects of Research Involving Polyploid Plants

    SciTech Connect (OSTI)

    Yang, Xiaohan [ORNL; Ye, Chuyu [ORNL; Tschaplinski, Timothy J [ORNL; Wullschleger, Stan D [ORNL; Tuskan, Gerald A [ORNL

    2011-01-01

    Almost all extant plant species have spontaneously doubled their genomes at least once in their evolutionary histories, resulting in polyploidy which provided a rich genomic resource for evolutionary processes. Moreover, superior polyploid clones have been created during the process of crop domestication. Polyploid plants generated by evolutionary processes and/or crop domestication have been the intentional or serendipitous focus of research dealing with the dynamics and consequences of genome evolution. One of the new trends in genomics research is to create synthetic polyploid plants which provide materials for studying the initial genomic changes/responses immediately after polyploid formation. Polyploid plants are also used in functional genomics research to study gene expression in a complex genomic background. In this review, we summarize the recent progress in genomics research involving ancient, young, and synthetic polyploid plants, with a focus on genome size evolution, genomics diversity, genomic rearrangement, genetic and epigenetic changes in duplicated genes, gene discovery, and comparative genomics. Implications on plant sciences including evolution, functional genomics, and plant breeding are presented. It is anticipated that polyploids will be a regular subject of genomics research in the foreseeable future as the rapid advances in DNA sequencing technology create unprecedented opportunities for discovering and monitoring genomic and transcriptomic changes in polyploid plants. The fast accumulation of knowledge on polyploid formation, maintenance, and divergence at whole-genome and subgenome levels will not only help plant biologists understand how plants have evolved and diversified, but also assist plant breeders in designing new strategies for crop improvement.

  13. Model documentation report: Transportation sector model of the National Energy Modeling System

    SciTech Connect (OSTI)

    1997-02-01

    Over the past year, several modifications have been made to the NEMS Transportation Model, incorporating greater levels of detail and analysis in modules previously represented in the aggregate or under a profusion of simplifying assumptions. This document is intended to amend those sections of the Model Documentation Report (MDR) which describe these superseded modules. Significant changes have been implemented in the LDV Fuel Economy Model, the Alternative Fuel Vehicle Model, the LDV Fleet Module, and the Highway Freight Model. The relevant sections of the MDR have been extracted from the original document, amended, and are presented in the following pages. A brief summary of the modifications follows: In the Fuel Economy Model, modifications have been made which permit the user to employ more optimistic assumptions about the commercial viability and impact of selected technological improvements. This model also explicitly calculates the fuel economy of an array of alternative fuel vehicles (AFV`s) which are subsequently used in the estimation of vehicle sales. In the Alternative Fuel Vehicle Model, the results of the Fuel Economy Model have been incorporated, and the program flows have been modified to reflect that fact. In the Light Duty Vehicle Fleet Module, the sales of vehicles to fleets of various size are endogenously calculated in order to provide a more detailed estimate of the impacts of EPACT legislation on the sales of AFV`s to fleets. In the Highway Freight Model, the previous aggregate estimation has been replaced by a detailed Freight Truck Stock Model, where travel patterns, efficiencies, and energy intensities are estimated by industrial grouping. Several appendices are provided at the end of this document, containing data tables and supplementary descriptions of the model development process which are not integral to an understanding of the overall model structure.

  14. Surface interactions involved in flashover with high density electronegative gases.

    SciTech Connect (OSTI)

    Hodge, Keith Conquest; Warne, Larry Kevin; Jorgenson, Roy Eberhardt; Wallace, Zachariah Red; Lehr, Jane Marie

    2010-01-01

    This report examines the interactions involved with flashover along a surface in high density electronegative gases. The focus is on fast ionization processes rather than the later time ionic drift or thermalization of the discharge. A kinetic simulation of the gas and surface is used to examine electron multiplication and includes gas collision, excitation and ionization, and attachment processes, gas photoionization and surface photoemission processes, as well as surface attachment. These rates are then used in a 1.5D fluid ionization wave (streamer) model to study streamer propagation with and without the surface in air and in SF6. The 1.5D model therefore includes rates for all these processes. To get a better estimate for the behavior of the radius we have studied radial expansion of the streamer in air and in SF6. The focus of the modeling is on voltage and field level changes (with and without a surface) rather than secondary effects, such as, velocities or changes in discharge path. An experiment has been set up to carry out measurements of threshold voltages, streamer velocities, and other discharge characteristics. This setup includes both electrical and photographic diagnostics (streak and framing cameras). We have observed little change in critical field levels (where avalanche multiplication sets in) in the gas alone versus with the surface. Comparisons between model calculations and experimental measurements are in agreement with this. We have examined streamer sustaining fields (field which maintains ionization wave propagation) in the gas and on the surface. Agreement of the gas levels with available literature is good and agreement between experiment and calculation is good also. Model calculations do not indicate much difference between the gas alone versus the surface levels. Experiments have identified differences in velocity between streamers on the surface and in the gas alone (the surface values being larger).

  15. Implementing an Employee Involvement Program Through an Innovation Competition

    E-Print Network [OSTI]

    Salichs, José G.

    2006-05-19

    . It is on these areas that it must be especially innovative to get advantage over its competitors. Moving in this direction, many organizations have recognized that the clue to innovation is employee involvement; an involvement that translates into assertive corporate...

  16. Solving convex problems involving powers using conic optimization

    E-Print Network [OSTI]

    Glineur, François

    Solving convex problems involving powers using conic optimization and a new self-concordant barrier CFG 07 Heidelberg University CFG 07 Solving convex problems involving powers using conic optimization remarks Future plans CFG 07 Solving convex problems involving powers using conic optimization 2 #12

  17. A Survey of Industrial Involvement in Open Source

    E-Print Network [OSTI]

    A Survey of Industrial Involvement in Open Source Øyvind Hauge and Andreas Røsdal {oyvind of industrial involvement in open source. The survey is performed in collaboration with participants from). The survey was performed to explore aspects of industrial involvement in open source, as industrial

  18. PRECLINICAL STUDY Prediction of lymph node involvement in breast cancer

    E-Print Network [OSTI]

    PRECLINICAL STUDY Prediction of lymph node involvement in breast cancer from primary tumor tissue- ther lymph node involvement in breast cancer is influenced by gene or miRNA expression of the primary tissue from a group of 96 breast cancer patients balanced for lymph node involvement using Affymetrix

  19. Hydrogen Bonds Involved in Binding the Qi-site Semiquinone in the bc1 Complex, Identified through Deuterium Exchange

    E-Print Network [OSTI]

    Crofts, Antony R.

    Hydrogen Bonds Involved in Binding the Qi-site Semiquinone in the bc1 Complex, Identified through them. The strength of interactions indicates that the protons are involved in hydrogen bonds with SQ. The hyperfine cou- plings differ from values typical for in-plane hydrogen bonds previously observed in model

  20. Distributional properties of Euclidean distances in wireless networks involving road systems

    E-Print Network [OSTI]

    Schmidt, Volker

    1 Distributional properties of Euclidean distances in wireless networks involving road systems of large wireless networks. The network geometry is modelled by random geometric graphs, and the locations are closely related with the interference geometry and, consequently, the performance of wireless networks

  1. Electronic spectroscopy of intermediates involved in the conversion of methane to methanol by FeO

    E-Print Network [OSTI]

    Metz, Ricardo B.

    Electronic spectroscopy of intermediates involved in the conversion of methane to methanol by Fe.1063/1.1448489 I. INTRODUCTION The direct oxidation of methane to an easily transport- able liquid such as methanol process and as the simplest model for alkane oxidation.1,2 Although no direct, efficient methane­methanol

  2. Microsoft Word - Number of Public Involvement Deliverables _2...

    National Nuclear Security Administration (NNSA)

    numerous (+150) video clips and raw video * Maintain the Public Involvement portion of web-based Environmental Management Information System (includes uploading briefings,...

  3. Probative Investigation of the Thermal Stability of Wastes Involved...

    Office of Environmental Management (EM)

    the Thermal Stability of Wastes Involved in February 2014 Waste Isolation Pilot Plant (WIPP) Waste Drum Breach Event Probative Investigation of the Thermal Stability of Wastes...

  4. RESEARCH INVOLVING HUMANS University Policy No.: RH8105

    E-Print Network [OSTI]

    Victoria, University of

    1 RESEARCH INVOLVING HUMANS University Policy No.: RH8105 Classification: Research Approving: Mandated Review: September, 2017 Associated Procedures Procedures for Conducting Human Research PURPOSE 1.00 The purpose of this policy is to: a) set out provisions to ensure Research Involving Human Participants

  5. UNLV DIVISION OF RESEARCH POLICY ON RESEARCH INVOLVING HUMAN SUBJECTS

    E-Print Network [OSTI]

    Walker, Lawrence R.

    UNLV DIVISION OF RESEARCH POLICY ON RESEARCH INVOLVING HUMAN SUBJECTS RESPONsmLE ADMINISTRATOR: VICE PRESIDENT FOR RESEARCH RESPONSmLE OFFICE(S): OFFICE OF RESEARCH INTEGRITY - HUMAN SUBJECTS rules and procedures, when conducting research involving human subjects. ENTITIES AFFECTED BY Tms POLICY

  6. Voluntary Associations and Their Involvement in Collaborative Forest Management 

    E-Print Network [OSTI]

    Lu, Jiaying

    2012-02-14

    . This dissertation was aimed at gaining a better understanding of outdoor recreation and environmental voluntary associations and their involvement in collaborative forest management. Five objectives guided this study: (1) assessing the organizational characteristics...

  7. Getting Involved in Manufacturing Day – College Educators Edition Webinar

    Broader source: Energy.gov [DOE]

    This webinar will help address questions on why and how community colleges, universities, and technical schools can get involved with MFG DAY.  Led by MFG DAY Co-Producers, the webinar will also...

  8. An exploration of meaningful involvement in ropes course programs 

    E-Print Network [OSTI]

    Haras, Katryna Stephanie

    2004-09-30

    Ropes course programs provide numerous benefits but what makes programs effective has been unclear. The purpose of the study was to: 1) determine if there was a measurable difference in meaningful involvement between the ...

  9. A fast enriched FEM for Poisson equations involving interfaces

    E-Print Network [OSTI]

    Huynh, Thanh Le Ngoc

    2008-01-01

    We develop a fast enriched finite element method for solving Poisson equations involving complex geometry interfaces by using regular Cartesian grids. The presence of interfaces is accounted for by developing suitable jump ...

  10. Documentation of the DRI Model of the US economy, December 1993

    SciTech Connect (OSTI)

    Not Available

    1994-02-28

    The Energy Information Administration (EIA) uses models of the US economy developed by Data Resources, Inc. (DRI) for conducting policy analyses, preparing forecasts for the Annual Energy Outlook, the Short-Term Energy Outlook, and related analyses in conjunction with EIA`s National Energy Modeling System (NEMS) and its other energy market models. Both the DRI Model of the US Economy and the DRI Personal Computer Input-Output Model (PC-IO){sup 2} were developed and are maintained by DRI as proprietary models. This report provides documentation, as required by EIA standards for the use of proprietary models; describes the theoretical basis, structure and functions of both DRI models; and contains brief descriptions of the models and their equations. Appendix A describes how the two large-scale models documented here are used to support the macroeconomic and interindustry modeling associated with the National Energy Modeling System. Appendix B is an article by Stephen McNees of the Federal Reserve Bank of Boston on ``How Large are Economic Forecast Errors.`` This article assesses the forecast accuracy of a number of economic forecasting models (groups) and is attached as an independent assessment of the forecast accuracy of the DRI Model of the US Economy.

  11. Model documentation natural gas transmission and distribution model (NGTDM) of the national energy modeling system. Volume II: Model developer`s report

    SciTech Connect (OSTI)

    Not Available

    1995-01-03

    To partially fulfill the requirements for {open_quotes}Model Acceptance{close_quotes} as stipulated in EIA Standard 91-01-01 (effective February 3, 1991), the Office of Integrated Analysis and Forecasting has conducted tests of the Natural Gas Transmission and Distribution Model (NGTDM) for the specific purpose of validating the forecasting model. This volume of the model documentation presents the results of {open_quotes}one-at-a-time{close_quotes} sensitivity tests conducted in support of this validation effort. The test results are presented in the following forms: (1) Tables of important model outputs for the years 2000 and 2010 are presented with respect to change in each input from the reference case; (2) Tables of percent changes from base case results for the years 2000 and 2010 are presented for important model outputs; (3) Tables of conditional sensitivities (percent change in output/percent change in input) for the years 2000 and 2010 are presented for important model outputs; (4) Finally, graphs presenting the percent change from base case results for each year of the forecast period are presented for selected key outputs. To conduct the sensitivity tests, two main assumptions are made in order to test the performance characteristics of the model itself and facilitate the understanding of the effects of the changes in the key input variables to the model on the selected key output variables: (1) responses to the amount demanded do not occur since there are no feedbacks of inputs from other NEMS models in the stand-alone NGTDM run. (2) All the export and import quantities from and to Canada and Mexico, and liquefied natural gas (LNG) imports and exports are held fixed (i.e., there are no changes in imports and exports between the reference case and the sensitivity cases) throughout the forecast period.

  12. Community assessments: Road maps to successful public involvement

    SciTech Connect (OSTI)

    Forrest, C.J. [Equinox Environmental Consultants, Wheaton, IL (United States)

    1995-12-01

    This paper presents a framework for performing comprehensive community assessments to increase the effectiveness of public involvement efforts. The community assessment process involves systematic and critical examination of beliefs, attitudes, opinions and knowledge of the many groups in the community. A good community assessment gathers information on the concerns or issues directly related to an environmental project as well as other important community issues to ensure development of an effective public involvement program. The framework discusses types of people and organizations that should be included in the community assessment interview process. It also delineates steps that persons charged with performing assessments can take to ensure that the views of all potential stakeholders are included--a necessary consideration in communities that are ethnically, racially, or economically diverse. Lastly, the framework discusses types of written materials that can be analyzed for additional insight into communities. For example, it discusses methods for reviewing past issues of the local newspaper to provide both validation of the information gathered during interviews and an understanding of the ways that community members give and receive information and respond to conflict or perceived threats. This framework is designed to show environmental professionals who are responsible for public involvement how to perform an initial community assessment. It provides illustrations of instances in which information vital to a successful public involvement effort has been uncovered through a careful assessment of the community. Both the U.S. EPA and the public have made clear their intentions to require increased public involvement. Many of these efforts will succeed or fail based on how well those charged with the public involvement component of environmental projects identify community issues and design communications programs that successfully reach all stakeholders.

  13. Final report on the public involvement process phase 1, Monitored Retrievable Storage Facility Feasibility Study

    SciTech Connect (OSTI)

    Moore, L.; Shanteau, C.

    1992-12-01

    This report summarizes the pubic involvement component of Phase 1 of the Monitored Retrievable Storage Facility (NM) Feasibility Study in San Juan County, Utah. Part of this summary includes background information on the federal effort to locate a voluntary site for temporary storage of nuclear waste, how San Juan County came to be involved, and a profile of the county. The heart of the report, however, summarizes the activities within the public involvement process, and the issues raised in those various forums. The authors have made every effort to reflect accurately and thoroughly all the concerns and suggestions expressed to us during the five month process. We hope that this report itself is a successful model of partnership with the citizens of the county -- the same kind of partnership the county is seeking to develop with its constituents. Finally, this report offers some suggestions to both county officials and residents alike. These suggestions concern how decision-making about the county's future can be done by a partnership of informed citizens and listening decision-makers. In the Appendix are materials relating to the public involvement process in San Juan County.

  14. Final report on the public involvement process phase 1, Monitored Retrievable Storage Facility Feasibility Study

    SciTech Connect (OSTI)

    Moore, L.; Shanteau, C.

    1992-12-01

    This report summarizes the pubic involvement component of Phase 1 of the Monitored Retrievable Storage Facility (NM) Feasibility Study in San Juan County, Utah. Part of this summary includes background information on the federal effort to locate a voluntary site for temporary storage of nuclear waste, how San Juan County came to be involved, and a profile of the county. The heart of the report, however, summarizes the activities within the public involvement process, and the issues raised in those various forums. The authors have made every effort to reflect accurately and thoroughly all the concerns and suggestions expressed to us during the five month process. We hope that this report itself is a successful model of partnership with the citizens of the county -- the same kind of partnership the county is seeking to develop with its constituents. Finally, this report offers some suggestions to both county officials and residents alike. These suggestions concern how decision-making about the county`s future can be done by a partnership of informed citizens and listening decision-makers. In the Appendix are materials relating to the public involvement process in San Juan County.

  15. Projecting Fatalities in Crashes Involving Older Drivers, 20002025

    E-Print Network [OSTI]

    ORNL-6963 Projecting Fatalities in Crashes Involving Older Drivers, 2000­2025 Patricia S. Hu 2000 This research was funded by GM pursuant to an agreement between GM and the U.S. Department #12;#12;GM Project G.6 October 2000iii TABLE OF CONTENTS LIST OF FIGURES

  16. An Honors Thesis in English What does it involve?

    E-Print Network [OSTI]

    Martinez, Tony R.

    1 An Honors Thesis in English What does it involve? · Prospectus The prospectus is a document that establishes your intentions for your thesis and makes a strong case for why your project should constitute an Honors thesis. A strong thesis is usually a result of a well developed prospectus. Care and attention

  17. Research Summary Consultation and community involvement in forest planning

    E-Print Network [OSTI]

    Research Summary Consultation and community involvement in forest planning: research in Cranborne of the Forestry Commission's `Long-Term Forest Plan' process. It also builds on various investigations into stakeholder analysis and the use of participatory tools in relation to Forest Design Plans (FDPs). The NFNF

  18. A Protein Export Pathway Involving Escherichia coli Porins

    E-Print Network [OSTI]

    McIntosh, Lawrence P.

    Structure Article A Protein Export Pathway Involving Escherichia coli Porins Gerd Prehna,1,2 Guijin@byron.biochem.ubc.ca (N.C.J.S.) DOI 10.1016/j.str.2012.04.014 SUMMARY Escherichia coli export the protein Yeb common to all E. coli strains has been reported, the mechanism of export has remained unclear. Herein, we

  19. Arm Coordination in Octopus Crawling Involves Unique Motor Control Strategies

    E-Print Network [OSTI]

    Hochner, Binyamin

    Report Arm Coordination in Octopus Crawling Involves Unique Motor Control Strategies Highlights d Octopuses use unique strategies to coordinate their arms in crawling d They can crawl in any direction relative to the facing (body) direction d Arms create pushing thrust by simple shortening

  20. Patterns of Arm Muscle Activation Involved in Octopus Reaching Movements

    E-Print Network [OSTI]

    Hochner, Binyamin

    Patterns of Arm Muscle Activation Involved in Octopus Reaching Movements Yoram Gutfreund,1 Tamar, Stazione Zoologica "A. Dohrn," Naples 80121, Italy The extreme flexibility of the octopus arm allows a basic invariant motor structure: a bend traveling from the base of the arm toward the tip (Gutfreund et

  1. BARNARD COLLEGE Termination of a Research Protocol Involving Human Subjects

    E-Print Network [OSTI]

    BARNARD COLLEGE Termination of a Research Protocol Involving Human Subjects Title: Principal) Study subjects: A total of _____ subjects were enrolled since the last report to the IRB. Since initial study approval on _____________ a total of _____ subjects have been enrolled in this study and ____ have

  2. Research Article Acetylcholinesterase in intestinal cell differentiation involves

    E-Print Network [OSTI]

    Tian, Weidong

    involved in the terminal differentiation of enterocytes. Butyrate, a short-chain fatty acid produced cell line Caco-2 following exposure to sodium butyrate (NaBT), using alkaline phosphatase (ALP, butyrate sodium, G2/M. Introduction The epithelium of the gastrointestinal tract is a complex and dynamic

  3. A1D04: Committee on Public Involvement in Transportation State of the Practice: White Paper on Public Involvement

    E-Print Network [OSTI]

    Handy, Susan L.

    -West Gateway Coordinating Council Public involvement is the process of two-way communication between citizen the passage of the Intermodal Surface Transportation Efficiency Act of 1991 (ISTEA), there has been underserved populations. ISTEA's directive was reinforced by the passage of the Transportation Equity Act

  4. Workplace Charging Challenge Partner: JLA Public Involvement | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on DeliciousMathematics And Statistics » USAJobs SearchAMERICA'SEnergyof Energy JLA Public Involvement Workplace

  5. Listening, talking triumph in promoting effective public involvement

    SciTech Connect (OSTI)

    Forrest, C.J. [Equinox Environmental Consultants Ltd., Wheaton, IL (United States); Michaud, G.R. [Illinois Environmental Protection Agency`s, Springfield, IL (United States). Office of Community Relations

    1995-07-01

    When added to situations involving formal Superfund cleanups, RCRA permitting and other environmental issues, it is clear that understanding how to handle community concerns is rapidly becoming a necessity for many businesses. The terms public involvement, public participation and community relations all embody the same concept--establishing a dialogue with members of the public who are affected by environmental permitting, a contaminated site or other environmental issues. The goal of the dialogue is to promote public understanding about a project or issue, and ensure that citizens` concerns are considered and thoroughly addressed. Public concerns often are magnified by lack of information, misinformation or false information about an environmental issue. Failing to acknowledge concerns and provide appropriate information can lead to community resistance. In their extreme forms, such communications failures have slowed or blocked the permitting process, and even halted removal of hazardous wastes from residential and nonresidential areas. Community relations requirements under the Comprehensive Environmental Response, Compensation and Liability Act, and public participation requirements under the Resource Conservation and Recovery Act are intended to promote positive dialogue. In both cases, core activities and their timing are set by regulation.

  6. Optical model potentials involving loosely bound p-shell nuclei around 10 MeV/nucleon 

    E-Print Network [OSTI]

    Trache, L.; Azhari, A.; Clark, HL; Gagliardi, Carl A.; Lui, YW; Mukhamedzhanov, AM; Tribble, Robert E.; Carstoiu, F.

    2000-01-01

    were used: M3Y with zero range and finite range exchange term, two density dependent versions of M3Y and the effective interaction of Jeukenne, Lejeune, and Mahaux. We find that the latter one, which has an independent imaginary part, gives the best...

  7. Report on International Collaboration Involving the FE Heater and HG-A Tests at Mont Terri

    SciTech Connect (OSTI)

    Houseworth, Jim; Rutqvist, Jonny; Asahina, Daisuke; Chen, Fei; Vilarrasa, Victor; Liu, Hui-Hai; Birkholzer, Jens

    2013-11-06

    Nuclear waste programs outside of the US have focused on different host rock types for geological disposal of high-level radioactive waste. Several countries, including France, Switzerland, Belgium, and Japan are exploring the possibility of waste disposal in shale and other clay-rich rock that fall within the general classification of argillaceous rock. This rock type is also of interest for the US program because the US has extensive sedimentary basins containing large deposits of argillaceous rock. LBNL, as part of the DOE-NE Used Fuel Disposition Campaign, is collaborating on some of the underground research laboratory (URL) activities at the Mont Terri URL near Saint-Ursanne, Switzerland. The Mont Terri project, which began in 1995, has developed a URL at a depth of about 300 m in a stiff clay formation called the Opalinus Clay. Our current collaboration efforts include two test modeling activities for the FE heater test and the HG-A leak-off test. This report documents results concerning our current modeling of these field tests. The overall objectives of these activities include an improved understanding of and advanced relevant modeling capabilities for EDZ evolution in clay repositories and the associated coupled processes, and to develop a technical basis for the maximum allowable temperature for a clay repository. The R&D activities documented in this report are part of the work package of natural system evaluation and tool development that directly supports the following Used Fuel Disposition Campaign (UFDC) objectives: ? Develop a fundamental understanding of disposal-system performance in a range of environments for potential wastes that could arise from future nuclear-fuel-cycle alternatives through theory, simulation, testing, and experimentation. ? Develop a computational modeling capability for the performance of storage and disposal options for a range of fuel-cycle alternatives, evolving from generic models to more robust models of performance assessment. For the purpose of validating modeling capabilities for thermal-hydro-mechanical (THM) processes, we developed a suite of simulation models for the planned full-scale FE Experiment to be conducted in the Mont Terri URL, including a full three-dimensional model that will be used for direct comparison to experimental data once available. We performed for the first time a THM analysis involving the Barcelona Basic Model (BBM) in a full three-dimensional field setting for modeling the geomechanical behavior of the buffer material and its interaction with the argillaceous host rock. We have simulated a well defined benchmark that will be used for codeto- code verification against modeling results from other international modeling teams. The analysis highlights the complex coupled geomechanical behavior in the buffer and its interaction with the surrounding rock and the importance of a well characterized buffer material in terms of THM properties. A new geomechanical fracture-damage model, TOUGH-RBSN, was applied to investigate damage behavior in the ongoing HG-A test at Mont Terri URL. Two model modifications have been implemented so that the Rigid-Body-Spring-Network (RBSN) model can be used for analysis of fracturing around the HG-A microtunnel. These modifications are (1) a methodology to compute fracture generation under compressive stress conditions and (2) a method to represent anisotropic elastic and strength properties. The method for computing fracture generation under compressive load produces results that roughly follow trends expected for homogeneous and layered systems. Anisotropic properties for the bulk rock were represented in the RBSN model using layered heterogeneity and gave bulk material responses in line with expectations. These model improvements were implemented for an initial model of fracture damage at the HG-A test. While the HG-A test model results show some similarities with the test observations, differences between the model results and observations remain.

  8. Involvement in Early Childhood Special Education Among Chinese and Non-Chinese American Parents

    E-Print Network [OSTI]

    SooHoo, Tanya

    2012-01-01

    in early childhood special education: Opportunities forInvolvement in Early Childhood Special Education AmongInvolvement in Early Childhood Special Education Among

  9. Product-Process Development Simulation to Support Specialty Contractor Involvement in Early Design

    E-Print Network [OSTI]

    Tommelein, Iris D.

    design of architecture-engineering-construction (AEC) products. Lean construction theory advocates such involvement. The practice of involving suppliers in product development and in manufacturing has proven

  10. Involvement of purinergic system in inflammation and toxicity induced by copper in zebrafish larvae

    SciTech Connect (OSTI)

    Leite, Carlos Eduardo, E-mail: carlos.leite@pucrs.br [Instituto de Toxicologia e Farmacologia, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, CEP 90619-900 (Brazil); Programa de Pós-Graduação em Medicina: Ciências Médicas, Universidade Federal do Rio Grande do Sul, Porto Alegre, CEP 90035-003 (Brazil); Maboni, Lucas de Oliveira [Instituto de Toxicologia e Farmacologia, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, CEP 90619-900 (Brazil); Faculdade de Biociências, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, CEP 90619-900 (Brazil); Cruz, Fernanda Fernandes [Instituto de Toxicologia e Farmacologia, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, CEP 90619-900 (Brazil); Faculdade de Farmácia, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, CEP 90619-900 (Brazil); Rosemberg, Denis Broock [Programa de Pós-graduação em Ciências Ambientais, Universidade Comunitária da Região de Chapecó, Chapecó, CEP 89809-000 (Brazil); and others

    2013-11-01

    The use of zebrafish (Danio rerio) is increasing as an intermediate preclinical model, to prioritize drug candidates for mammalian testing. As the immune system of the zebrafish is quite similar to that of mammals, models of inflammation are being developed for the screening of new drugs. The characterization of these models is crucial for studies that seek for mechanisms of action and specific pharmacological targets. It is well known that copper is a metal that induces damage and cell migration to hair cells of lateral line of zebrafish. Extracellular nucleotides/nucleosides, as ATP and adenosine (ADO), act as endogenous signaling molecules during tissue damage by exerting effects on inflammatory and immune responses. The present study aimed to characterize the inflammatory status, and to investigate the involvement of the purinergic system in copper-induced inflammation in zebrafish larvae. Fishes of 7 days post-fertilization were exposed to 10 ?M of copper for a period of 24 h. The grade of oxidative stress, inflammatory status, copper uptake, the activity and the gene expression of the enzymes responsible for controlling the levels of nucleotides and adenosine were evaluated. Due to the copper accumulation in zebrafish larvae tissues, the damage and oxidative stress were exacerbated over time, resulting in an inflammatory process involving IL-1?, TNF-?, COX-2 and PGE{sub 2}. Within the purinergic system, the mechanisms that control the ADO levels were the most involved, mainly the reactions performed by the isoenzyme ADA 2. In conclusion, our data shed new lights on the mechanisms related to copper-induced inflammation in zebrafish larvae. - Graphical abstract: This scheme provides a chronological proposition for the biochemical events induced by copper in zebrafish larvae. The dashed line shows the absorption of copper over the exposure time. After 1 h of exposure to copper, the release of PGE{sub 2} occurs, followed by an increase of MPO (as a consequence of neutrophil migration), increased expression of genes involved in inflammatory events (IL-1? and TNF-?) and, reduction of the anti-inflammatory cytokine IL-10 at 4 h. At 24 h, the copper concentration is found highly increased, what is coincident with oxidative stress. Regarding the purinergic system, it is possible to observe an inhibition of ecto-5?-NT and ADA, with the consequent increase of AMP and ADA, respectively, at 24 h. The expression of enzyme-related genes shows a decrease in the expression of ecto-5?-NT and variable expressions of ADA subfamily enzymes. - Highlights: • Copper led to increased oxidative stress, and decreased the antioxidants' defenses. • Copper induced time-related changes of IL-1?, TNF-?, IL-10 and PGE{sub 2} levels. • ADA activity controls the levels of adenosine in copper-induced inflammation. • ADA 2 is the main ADA subfamily involved. • The purinergic system seems to be involved in the resolution of inflammation.

  11. File under: H Web name: Human Subjects, Policy on Research Involving [June 29, 2000] Official name: Policy on Research Involving Human Subjects [June 29, 2000] Location

    E-Print Network [OSTI]

    Prodiæ, Aleksandar

    File under: H Web name: Human Subjects, Policy on Research Involving [June 29, 2000] Official name: Policy on Research Involving Human Subjects [June 29, 2000] Location: https://share.utorcsi.utoronto.ca/sites/gc/Governing%20Council/All%20Policies/H/Human%20Subjects,%20Policy%20on%20Research %20Involving.docx [Official

  12. Boosting cooperation by involving extortion in spatial Prisoner's dilemma

    E-Print Network [OSTI]

    Wu, Zhi-Xi

    2014-01-01

    We study the evolution of cooperation in spatial Prisoner's dilemma games with and without extortion by adopting aspiration-driven strategy updating rule. We focus explicitly on how the strategy updating manner (whether synchronous or asynchronous) and also the introduction of extortion strategy affect the collective outcome of the games. By means of Monte Carlo (MC) simulations as well as dynamical cluster techniques, we find that the involvement of extortioners facilitates the boom of cooperators in the population (and whom can always dominate the population if the temptation to defect is not too large) for both synchronous and asynchronous strategy updating, in stark contrast to the otherwise case, where cooperation is promoted for intermediate aspiration level with synchronous strategy updating, but is remarkably inhibited if the strategy updating is implemented asynchronously. We explain the results by configurational analysis and find that the presence of extortion leads to the checkerboard-like orderin...

  13. Arc Plasma Torch Modeling

    E-Print Network [OSTI]

    Trelles, J P; Vardelle, A; Heberlein, J V R

    2013-01-01

    Arc plasma torches are the primary components of various industrial thermal plasma processes involving plasma spraying, metal cutting and welding, thermal plasma CVD, metal melting and remelting, waste treatment and gas production. They are relatively simple devices whose operation implies intricate thermal, chemical, electrical, and fluid dynamics phenomena. Modeling may be used as a means to better understand the physical processes involved in their operation. This paper presents an overview of the main aspects involved in the modeling of DC arc plasma torches: the mathematical models including thermodynamic and chemical non-equilibrium models, turbulent and radiative transport, thermodynamic and transport property calculation, boundary conditions and arc reattachment models. It focuses on the conventional plasma torches used for plasma spraying that include a hot-cathode and a nozzle anode.

  14. EIA model documentation: Documentation of the Oil and Gas Supply Module (OGSM)

    SciTech Connect (OSTI)

    1997-01-01

    The purpose of this report is to define the objectives of the Oil and Gas Supply Model (OGSM), to describe the model`s basic approach, and to provide detail on how the model works. This report is intended as a reference document for model analysts, users, and the public. Projected production estimates of US crude oil and natural gas are based on supply functions generated endogenously within National Energy Modeling System (NEMS) by the OGSM. OGSM encompasses domestic crude oil and natural gas supply by both conventional and nonconventional recovery techniques. Nonconventional recovery includes enhanced oil recovery (EOR), and unconventional gas recovery (UGR) from tight gas formations, Devonian shale and coalbeds. Crude oil and natural gas projects are further disaggregated by geographic region. OGSM projects US domestic oil and gas supply for six Lower 48 onshore regions, three offshore regions, and Alaska. The general methodology relies on forecasted drilling expenditures and average drilling costs to determine exploratory and developmental drilling levels for each region and fuel type. These projected drilling levels translate into reserve additions, as well as a modification of the production capacity for each region. OGSM also represents foreign trade in natural gas, imports and exports by entry region.

  15. Renewable Energy and Efficiency Modeling Analysis Partnership: An Analysis of How Different Energy Models Addressed a Common High Renewable Energy Penetration Scenario in 2025

    E-Print Network [OSTI]

    Blair, N.

    2010-01-01

    taken from EIA’s Annual Energy Outlook (AEO), 20% windon Renewable Energy Annual Energy Outlook Argonne NationalNEMS for the 2006 Annual Energy Outlook (AEO). (Note: The

  16. Examining the consistency relations describing the three-point functions involving tensors

    SciTech Connect (OSTI)

    Sreenath, V.; Sriramkumar, L., E-mail: sreenath@physics.iitm.ac.in, E-mail: sriram@physics.iitm.ac.in [Department of Physics, Indian Institute of Technology Madras, Chennai 600036 (India)

    2014-10-01

    It is well known that the non-Gaussianity parameter f{sub NL} characterizing the scalar bi-spectrum can be expressed in terms of the scalar spectral index in the squeezed limit, a property that is referred to as the consistency relation. In contrast to the scalar bi-spectrum, the three-point cross-correlations involving scalars and tensors and the tensor bi-spectrum have not received adequate attention, which can be largely attributed to the fact that the tensors had remained undetected at the level of the power spectrum until very recently. The detection of the imprints of the primordial tensor perturbations by BICEP2 and its indication of a rather high tensor-to-scalar ratio, if confirmed, can open up a new window for understanding the tensor perturbations, not only at the level of the power spectrum, but also in the realm of non-Gaussianities. In this work, we consider the consistency relations associated with the three-point cross-correlations involving scalars and tensors as well as the tensor bi-spectrum in inflationary models driven by a single, canonical, scalar field. Characterizing the cross-correlations in terms of the dimensionless non-Gaussianity parameters C{sub NL}{sup R} and C{sub NL}{sup ?} that we had introduced earlier, we express the consistency relations governing the cross-correlations as relations between these non-Gaussianity parameters and the scalar or tensor spectral indices, in a fashion similar to that of the purely scalar case. We also discuss the corresponding relation for the non-Gaussianity parameter h{sub NL} used to describe the tensor bi-spectrum. We analytically establish these consistency relations explicitly in the following two situations: a simple example involving a specific case of power law inflation and a non-trivial scenario in the so-called Starobinsky model that is governed by a linear potential with a sharp change in its slope. We also numerically verify the consistency relations in three types of inflationary models that permit deviations from slow roll and lead to scalar power spectra with features which typically result in an improved fit to the data than the more conventional, nearly scale invariant, spectra. We close with a summary of the results we have obtained.

  17. Representation of analysis results involving aleatory and epistemic uncertainty.

    SciTech Connect (OSTI)

    Johnson, Jay Dean; Helton, Jon Craig; Oberkampf, William Louis; Sallaberry, Cedric J.

    2008-08-01

    Procedures are described for the representation of results in analyses that involve both aleatory uncertainty and epistemic uncertainty, with aleatory uncertainty deriving from an inherent randomness in the behavior of the system under study and epistemic uncertainty deriving from a lack of knowledge about the appropriate values to use for quantities that are assumed to have fixed but poorly known values in the context of a specific study. Aleatory uncertainty is usually represented with probability and leads to cumulative distribution functions (CDFs) or complementary cumulative distribution functions (CCDFs) for analysis results of interest. Several mathematical structures are available for the representation of epistemic uncertainty, including interval analysis, possibility theory, evidence theory and probability theory. In the presence of epistemic uncertainty, there is not a single CDF or CCDF for a given analysis result. Rather, there is a family of CDFs and a corresponding family of CCDFs that derive from epistemic uncertainty and have an uncertainty structure that derives from the particular uncertainty structure (i.e., interval analysis, possibility theory, evidence theory, probability theory) used to represent epistemic uncertainty. Graphical formats for the representation of epistemic uncertainty in families of CDFs and CCDFs are investigated and presented for the indicated characterizations of epistemic uncertainty.

  18. Personnel involved in nuclear standards development: 1980 directory

    SciTech Connect (OSTI)

    Carr, S.J.

    1980-03-01

    The development of nuclear standards is an active and necessary endeavor that is concerned with the safe, orderly, and economic development of nuclear potential. There are almost 4100 people from the teachnical community who are presently involved either in writing nuclear standards, including codes, or in the management and processing roles necessary for their approval and promulgation. This document identifies the current participation of each individual as member, chairman, cochairman (vice-chairman), or secretary of about 700 standards development committees and groups. The standards committees and groups are identified with the organizations that are responsible for the preparation, review, and maintenance of the standards and that provide support through supervisory committees and headquarters staff. This directory includes four major sections: personnel, employers, committees, and a Key-Word-in-Context (KWIC) Index of committee titles. It can also be used to identify the participation of employers as well as to recognize the contributions of individuals to the often interdisciplinary activity of standards development.

  19. Projected Benefits of Federal Energy Efficiency and Renewable Energy Programs - FY 2004 – FY2020

    SciTech Connect (OSTI)

    None, None

    2004-04-01

    This report features results and data based on the National Energy Modeling System (NEMS) model, as well as EERE's benefits and Government Performance and Results Act (GPRA) guidance.

  20. Polo-like Kinase I is involved in Invasion through Extracellular Matrix

    SciTech Connect (OSTI)

    Bissell, Mina J; Rizki, Aylin; Mott, Joni D.; Bissell, Mina J

    2008-04-02

    Polo-like kinase 1, PLK1, has important functions in maintaining genome stability and is involved in regulation of mitosis. PLK1 is up regulated in many invasive carcinomas. We asked whether it may also play a role in acquisition of invasiveness, a crucial step in transition to malignancy. In a model of metaplastic basal-like breast carcinoma progression, we found that PLK1 expression is necessary but not sufficient to induce invasiveness through laminin-rich extracellular matrix. PLK1 mediates invasion via Vimentin and {beta}1 integrin, both of which are necessary. We observed that PLK1 phosphorylates Vimentin on serine 82, which in turn regulates cell surface levels of {beta}1 integrin. We found PLK1 to be also highly expressed in pre-invasive in situ carcinomas of the breast. These results support a role for the involvement of PLK1 in the invasion process and point to this pathway as a potential therapeutic target for pre-invasive and invasive breast carcinoma treatment.

  1. Model Wind Ordinance for Local Governments

    Office of Energy Efficiency and Renewable Energy (EERE)

    In 2006, Pennsylvania developed a model local ordinance for wind energy facilities through a collaborative effort involving several state departments and stakeholder groups. The purpose of the...

  2. OSPREY Model

    SciTech Connect (OSTI)

    Veronica J. Rutledge

    2013-01-01

    The absence of industrial scale nuclear fuel reprocessing in the U.S. has precluded the necessary driver for developing the advanced simulation capability now prevalent in so many other countries. Thus, it is essential to model complex series of unit operations to simulate, understand, and predict inherent transient behavior and feedback loops. A capability of accurately simulating the dynamic behavior of advanced fuel cycle separation processes will provide substantial cost savings and many technical benefits. The specific fuel cycle separation process discussed in this report is the off-gas treatment system. The off-gas separation consists of a series of scrubbers and adsorption beds to capture constituents of interest. Dynamic models are being developed to simulate each unit operation involved so each unit operation can be used as a stand-alone model and in series with multiple others. Currently, an adsorption model has been developed within Multi-physics Object Oriented Simulation Environment (MOOSE) developed at the Idaho National Laboratory (INL). Off-gas Separation and REcoverY (OSPREY) models the adsorption of off-gas constituents for dispersed plug flow in a packed bed under non-isothermal and non-isobaric conditions. Inputs to the model include gas, sorbent, and column properties, equilibrium and kinetic data, and inlet conditions. The simulation outputs component concentrations along the column length as a function of time from which breakthrough data is obtained. The breakthrough data can be used to determine bed capacity, which in turn can be used to size columns. It also outputs temperature along the column length as a function of time and pressure drop along the column length. Experimental data and parameters were input into the adsorption model to develop models specific for krypton adsorption. The same can be done for iodine, xenon, and tritium. The model will be validated with experimental breakthrough curves. Customers will be given access to OSPREY to used and evaluate the model.

  3. Classroom simulation of public involvement in H.L.W. issues featuring STS concepts

    SciTech Connect (OSTI)

    Bieniawski, Z.T.

    1996-12-01

    This paper reports on a classroom experiment, now in its third year, conducted by the author for students involvement in High-Level Waste disposal. The project involved designing a methodology for HLW management in the United States.

  4. Kindergarten Transition: Does family involvement make a difference in children's early school adjustment?

    E-Print Network [OSTI]

    Kang, Jean

    2010-07-30

    in kindergarten and the specific outcomes of family involvement is still very limited. Using a combination of quantitative and qualitative research methods, this study aims to investigate the impact of family involvement in kindergarten transition on children...

  5. Subbasin Planning Public Involvement Plan 1 Last Revised: 4/4/2004

    E-Print Network [OSTI]

    Subbasin Planning Public Involvement Plan 1 Last Revised: 4/4/2004 Walla Walla, Tucannon, Asotin & Lower Snake River Subbasin Planning Public Involvement Plan Background Public outreach and involvement is key to the success of the subbasin planning process. Without public acceptance and support of the plan

  6. SMALL AND LARGE-SCALE MAGNETIC FIELDS INVOLVED WITH SOLAR FLARES

    E-Print Network [OSTI]

    ABSTRACT SMALL AND LARGE-SCALE MAGNETIC FIELDS INVOLVED WITH SOLAR FLARES by Chang Liu Solar flares of an EUV sigmoid. #12;SMALL AND LARGE-SCALE MAGNETIC FIELDS INVOLVED WITH SOLAR FLARES by Chang Liu RESERVED #12;APPROVAL PAGE SMALL AND LARGE-SCALE MAGNETIC FIELDS INVOLVED WITH SOLAR FLARES Chang Liu Dr

  7. Panel - Generic Longitudinal Business Process Model

    E-Print Network [OSTI]

    Barkow, Ingo; Block, William C.; Greenfield, Jay; Hebing, Marcel; Hoyle, Larry; Thomas, Wendy

    2013-04-03

    This presentation described a model for the processes involved in a longitudinal study. The model was developed at a symposium-style workshop held at Dagstuhl in September of 2011 (http://www.dagstuhl.de/11382). The Generic Longitudinal Business...

  8. What is the effect of 4-H involvement on levels of empathy, self-esteem, community involvement and positive view of the future on urban youth? 

    E-Print Network [OSTI]

    Bonnett, Erika Dawn

    2007-04-25

    -1 WHAT IS THE EFFECT OF 4-H INVOLVEMENT ON LEVELS OF EMPATHY, SELF-ESTEEM, COMMUNITY INVOLVEMENT AND POSITIVE VIEW OF THE FUTURE ON URBAN YOUTH? A Thesis by ERIKA DAWN BONNETT Submitted to the Office of Graduate Studies of Texas A...-ESTEEM, COMMUNITY INVOLVEMENT AND POSITIVE VIEW OF THE FUTURE ON URBAN YOUTH? A Thesis by ERIKA DAWN BONNETT Submitted to the Office of Graduate Studies of Texas A&M University in partial fulfillment of the requirements for the degree of MASTER...

  9. A New Coal-Permeability Model: Internal Swelling Stress and Fracture–Matrix Interaction

    E-Print Network [OSTI]

    Liu, Hui-Hai; Rutqvist, Jonny

    2010-01-01

    processes in coal seams involving coupled liquid ?ow andfor coupled liquid ?ow A New Coal-Permeability Model and

  10. Overview of NEMS-H2, Version 1.0 Frances Wood

    E-Print Network [OSTI]

    Pipeline Compr. H2 Truck Electrolysis Coal Gasification Biomass Gasification Small City Station Rural sequestration) · Coal Gasification (with and without sequestration) · Biomass Gasification · Electrolysis (grid Residential Renewables: Wind Biomass Solar Geothermal Uranium Commercial Industrial Transportation demands

  11. A sensitivity analysis of the treatment of wind energy in the AEO99 version of NEMS

    E-Print Network [OSTI]

    Osborn, Julie G.; Wood, Frances; Richey, Cooper; Sanders, Sandy; Short, Walter; Koomey, Jonathan

    2001-01-01

    Documentation Report: Wind Energy Submodule (WES). DOE/EIA-The Economic Value of Wind Energy at High Power SystemReference Case, 0.8 GW of wind energy are added between 2000

  12. A sensitivity analysis of the treatment of wind energy in the AEO99 version of NEMS

    E-Print Network [OSTI]

    Osborn, Julie G.; Wood, Frances; Richey, Cooper; Sanders, Sandy; Short, Walter; Koomey, Jonathan

    2001-01-01

    refers to the distance to tranmission lines. Existing 115 kVSTV SPP NWP RA CNV This tranmission extension cost is added

  13. Robust Power Control of Optical Links with Time-Delay Nem Stefanovic and Lacra Pavel

    E-Print Network [OSTI]

    Pavel, Lacra

    of Electrical and Computer Engineering, University of Toronto, Toronto, Ontario, Canada pavel-delays. Primal-dual control algorithms adjust the signal powers at the channel sources and receiver to optimize the OSNR values. The link utilization price is regularly updated and fed back to the source algorithms. We

  14. Review: Besedotvorni tematski blok na petnajstem mednarodnem slvisti?nem kongresu v Minsku (2013)

    E-Print Network [OSTI]

    Vorši?, Ines; Breznik, Irena Stramlji?

    2014-06-26

    ; NRPXQLNDFLMH#17;#3; .RW#3; MH#3; XJRWRYLOD#15;#3; LPD#3; OHNVLNDOQD#3; NUHD-­ WLYQRVW#3;Y#3;WRYUVWQLK#3;EHVHGLOLK#3;SUHGYVHP#3; VWLOLVWLþQR#3;YORJR#3; LQ#3; XþLQNXMH#3; ]ODVWL#3; KX-­ PRUQR#3;DOL#3;LURQLþQR#17; 5XVLQMD#3;*DOLQD#3;3#17;#3;1HãþLPHQNR#3; #11...; JD#3; RGUDåDMR#3; WYRUMHQNH#3;Y#3;MH]LNX#3;PHGLMHY#15;#3;]ODVWL#3;Y#3;SX-­ EOLFLVWLþQLK#3; LQ#3; RJODVQLK#3; EHVHGLOLK#17;#3;.RW#3; XJRWDYOMD#3;$UL]DQNRYVND#3;MH#3;IHQRPHQ#3;SX-­ EOLFLVWLþQHJD#3; MH]LND#3; LQ#3; MH]LND#3; RJODVRY#3; — 111 — 2FHQH#15;#3...

  15. A SENSITIVITY ANALYSIS OF THE TREATMENT OF WIND ENERGY IN THE AEO99 VERSION OF NEMS

    E-Print Network [OSTI]

    and market penetration on the U.S. Department of Energy's Annual Energy Outlook (AEO) forecast for wind technologies. The AEO's annual report of energy supply, demand, and prices through 2020 is based on resultsLBNL-44070 TP-28529 A SENSITIVITY ANALYSIS OF THE TREATMENT OF WIND ENERGY IN THE AEO99 VERSION

  16. Frequency Stabilization in Non-linear MEMS and NEMS Oscillators (IN-11-087)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverse (Journal Article)Forthcoming Upgrades toFreezing a Droplet to Stop- Energy

  17. U.S. Energy Information Administration NEMS Residential Demand Module Documentation Report 2011

    U.S. Energy Information Administration (EIA) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home PageMonthly","10/2015"4,"Ames5 Tables July 1996 Energy Information Administration Office of Coal,Demand Module of the NationalSales (Million Barrels)New

  18. A Tomato Detached Leaf Assay for Chemical Genomics of an HLB Model System

    E-Print Network [OSTI]

    Patne, S.; Eulgem, T.; Roose, M. L.

    2014-01-01

    Leaf Assay for Chemical Genomics of an HLB Model Systemapproach known as chemical genomics with Tomato “Psyllida model of HLB. Chemical genomics involves three key stages

  19. 01-12-1998 - Bench Top FIre Involving Use of Alcohol and Burner...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    1998 - Bench Top FIre Involving Use of Alcohol and Burner Document Number: NA Effective Date: 011998 File (public): 01-12-1998...

  20. Molecular genetic analysis of activation-tagged transcription factors thought to be involved in photomorphogenesis

    SciTech Connect (OSTI)

    Neff, Michael M.

    2011-06-23

    This is a final report for Department of Energy Grant No. DE-FG02-08ER15927 entitled “Molecular Genetic Analysis of Activation-Tagged Transcription Factors Thought to be Involved in Photomorphogenesis”. Based on our preliminary photobiological and genetic analysis of the sob1-D mutant, we hypothesized that OBP3 is a transcription factor involved in both phytochrome and cryptochrome-mediated signal transduction. In addition, we hypothesized that OBP3 is involved in auxin signaling and root development. Based on our preliminary photobiological and genetic analysis of the sob2-D mutant, we also hypothesized that a related gene, LEP, is involved in hormone signaling and seedling development.

  1. Modeling U.S. Energy Use Changes with Global Climate Change

    SciTech Connect (OSTI)

    Hadley, Stanton W; Erickson III, David J; Hernandez Figueroa, Jose L

    2006-09-01

    Using a general circulation model of Earth climate (PCM-IBIS) to drive an energy use model (DD-NEMS), we calculated the energy use changes for each year from 2003-2025 for the nine U.S. Census regions. We used five scenarios: 1) a reference with no change in temperatures from the 1970-2003 average, 2) a gradual 1 F rise in temperature by 2025, 3) a gradual 3 F rise by 2025, 4) a climate simulation with low temperature response to CO2 doubling in the atmosphere, and 5) a climate simulation with a more extreme response. The low-?T scenario had a cumulative reduction in energy of 2.1 Quads but an increase in cost of $14.8 billion. The northern states had reductions in cost over the entire period, but most other regions had increases in costs because increases in cooling costs outweighed reductions in heating and other energy uses. Higher temperature sensitivity resulted in increased warming, especially in the winter months. Because heating needs decreased, total energy requirements declined by a cumulative 4.2 Quads. However, total cost still increased $6.1 billion and carbon emissions still rose as coal-based electricity for cooling needs grew.

  2. Customer Involvement

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would like submit theCovalent Bonding inCustomer-Comments Sign In About |

  3. Getting Involved

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverse (Journalvivo Low-Dose Low LETUseful Links Useful Links:Get

  4. Insensitizing controls for a heat equation with a nonlinear term involving the state and the

    E-Print Network [OSTI]

    González Burgos, Manuel

    Insensitizing controls for a heat equation with a nonlinear term involving the state In this paper we present two results on the existence of insensitizing controls for a heat equation in a bounded domain of IRN . We first consider a semilinear heat equation involving gradient terms with homogeneous

  5. Inclusion of Human Subjects in Research Human Subjects Involvement and Characteristics

    E-Print Network [OSTI]

    Firestone, Jeremy

    Inclusion of Human Subjects in Research Human Subjects Involvement and Characteristics: · Describe the proposed involvement of human subjects in the work outlined in the Research Design and Methods section. · Describe the characteristics of the subject population, including their anticipated number, age range

  6. Abstract--Many large scale system blackouts involve relay misoperations. Traditional relay algorithms and settings need to

    E-Print Network [OSTI]

    1 Abstract--Many large scale system blackouts involve relay misoperations. Traditional relay-wide blackouts involve relay misoperations [1]. Evaluation and improvement of existing relay algorithms

  7. Summary Results for Brine Migration Modeling Performed by LANL...

    Energy Savers [EERE]

    modeling related to coupled processes involving brine and vapor migration in geologic salt, focusing on recent developments and studies conducted at Sandia, Los Alamos, and...

  8. Involvement of the transcription factor FoxM1 in contact inhibition

    SciTech Connect (OSTI)

    Faust, Dagmar; Al-Butmeh, Firas; Linz, Berenike [Institute of Toxicology, Medical Center of the Johannes Gutenberg-University, Obere Zahlbacherstr. 67, 55131 Mainz (Germany)] [Institute of Toxicology, Medical Center of the Johannes Gutenberg-University, Obere Zahlbacherstr. 67, 55131 Mainz (Germany); Dietrich, Cornelia, E-mail: cdietric@uni-mainz.de [Institute of Toxicology, Medical Center of the Johannes Gutenberg-University, Obere Zahlbacherstr. 67, 55131 Mainz (Germany)] [Institute of Toxicology, Medical Center of the Johannes Gutenberg-University, Obere Zahlbacherstr. 67, 55131 Mainz (Germany)

    2012-10-05

    Highlights: Black-Right-Pointing-Pointer The transcription factor FoxM1 is downregulated upon contact inhibition. Black-Right-Pointing-Pointer The decrease in FoxM1 levels occurs very likely due to inhibition of ERK activity. Black-Right-Pointing-Pointer The decrease in FoxM1 is not sufficient, but required for contact inhibition. Black-Right-Pointing-Pointer We propose a new model of contact inhibition involving pRB/E2F and FoxM1. -- Abstract: Contact inhibition is a crucial mechanism regulating proliferation in vitro and in vivo. Although it is generally accepted that contact inhibition plays a pivotal role in maintaining tissue homeostasis, the molecular mechanisms of contact inhibition are still not fully understood. FoxM1 is known as a proliferation-associated transcription factor and is upregulated in many cancer types. Vice versa, anti-proliferative signals, such as TGF-{beta} and differentiation signals decrease FoxM1 expression. Here we investigated the role of FoxM1 in contact inhibition in fibroblasts. We show that protein expression of FoxM1 is severely and rapidly downregulated upon contact inhibition, probably by inhibition of ERK activity, which then leads to decreased expression of cyclin A and polo-like kinase 1. Vice versa, ectopic expression of FoxM1 prevents the decrease in cyclin A and polo-like kinase 1 and causes a two-fold increase in saturation density indicating loss of contact inhibition. Hence, we show that downregulation of FoxM1 is required for contact inhibition by regulating expression of cyclin A and polo-like kinase 1.

  9. 2003 Yerkes Summer Institute Day Lab 1 Solar System Model page-1 Building Models to Scale

    E-Print Network [OSTI]

    Collar, Juan I.

    2003 Yerkes Summer Institute Day Lab 1 ­ Solar System Model page-1 Building Models to Scale visualize our solar neighborhood? One way is to build a scale model. Take, for example, the model of a BMW Z Introduction Can you picture the dimensions of the solar system? Probably not. The sizes and distances involved

  10. 13 CHAPTER XIII: PRICE ENDOGENOUS MODELING 13 CHAPTER XIII: PRICE ENDOGENOUS MODELING ................................................... 1

    E-Print Network [OSTI]

    McCarl, Bruce A.

    13 CHAPTER XIII: PRICE ENDOGENOUS MODELING 13 CHAPTER XIII: PRICE ENDOGENOUS MODELING.................................................................................................................... 16 #12;13.1 Introduction A common economic application of nonlinear programming involves price endogenous models. In the standard LP model, input and output prices or quantities are assumed fixed

  11. The interactive effects of individual learning style, computer software, and teacher involvement on developing typing skill 

    E-Print Network [OSTI]

    Goodman, Sarina Renae

    1995-01-01

    This research examines the effects and interactions of an individual's learning style, the type of computer software, and the level of teacher involvement on students learning how to type on a computer keyboard. The research ...

  12. Removing the HUD: The Impact of Non-Diegetic Game Elements and Expertise on Player Involvement

    E-Print Network [OSTI]

    Cairns, Paul

    Removing the HUD: The Impact of Non-Diegetic Game Elements and Expertise on Player Involvement-character can see and interact with; and the latter does not, e.g. classic heads-up displays (HUDs) showing

  13. Examination of offsite radiological emergency protective measures for nuclear reactor accidents involving core melt

    E-Print Network [OSTI]

    Aldrich, David C.

    1979-01-01

    Evacuation, sheltering followed by population relocation, and iodine prophylaxis are evaluated as offsite public protective measures in response to nuclear reactor accidents involving core-melt. Evaluations were conducted ...

  14. The obligation nation : America's involvement in the affairs of the World

    E-Print Network [OSTI]

    Francel, Leif (Leif G.)

    2012-01-01

    Does America have an obligation, whether through foreign aid, military involvement, or by spreading democracy, to change the world? This thesis answers these above questions in intimate detail through the moral framework ...

  15. Cold shock response of Salmonella enterica serovar typhimurium; the involvement of the CspA paralogues 

    E-Print Network [OSTI]

    Woodall, Katy Anna

    2011-11-24

    Salmonella enterica sv. typhimurium is a major food-borne pathogen, in part because of its ability to persist and multiply at low temperatures. Adaptation to refrigerated temperatures involves induction of a multigenic ...

  16. School-Based Family Involvement: Patterns and Predictors in the NLTS2 

    E-Print Network [OSTI]

    Frew, Leigh Ann

    2012-10-19

    This investigation used data from the National Longitudinal Transition Study 2 (NLTS2) to investigate patterns among student, family, and school characteristics, school outreach programs, and school-based family involvement for families of 5...

  17. A study of parental involvement and school climate: Perspective from the middle school 

    E-Print Network [OSTI]

    Dixon, Shantina Rayford

    2009-05-15

    This study examines school level differences on different dimensions of teacherrated parent involvement and school climate while adjusting for age, gender, ethnicity, how certified, and number of years teaching. Two hundred twenty-four elementary...

  18. Offline Memory Reprocessing: Involvement of the Brain's Default Network in Spontaneous Thought Processes

    E-Print Network [OSTI]

    Jiang,Tianzi

    Offline Memory Reprocessing: Involvement of the Brain's Default Network in Spontaneous Thought active during the task-free state. Interestingly, we found that offline reprocessing of previously integration and functional separation among its component regions to execute offline memory reprocessing

  19. IDENTIFICATIONS AND APPLICATIONS OF COUPLED CLIMATE MODELS

    E-Print Network [OSTI]

    Yu, Jin-Yi

    IDENTIFICATIONS AND APPLICATIONS OF COUPLED CLIMATE MODELS Jin-Yi Yu Department of Earth System of environmental system models. 1. Introduction The Earth climate system consists of several major components of global warming, all four components of the Earth climate system are involved. Coupled climate models

  20. Boolean models for genetic regulatory networks 

    E-Print Network [OSTI]

    Xiao, Yufei

    2009-05-15

    This dissertation attempts to answer some of the vital questions involved in the genetic regulatory networks: inference, optimization and robustness of the mathe- matical models. Network inference constitutes one of the central goals of genomic...

  1. Commodity market modeling and physical trading strategies

    E-Print Network [OSTI]

    Ellefsen, Per Einar

    2010-01-01

    Investment and operational decisions involving commodities are taken based on the forward prices of these commodities. These prices are volatile, and a model of their evolution must correctly account for their volatility ...

  2. Genome-wide assessment of the carriers involved in the cellular uptake of drugs: a model system in yeast.

    E-Print Network [OSTI]

    Lanthaler, Karin; Bilsland, Elizabeth; Dobson, Paul D; Moss, Harry J; Pir, Pinar; Kell, Douglas B; Oliver, Stephen G

    2011-10-24

    -mediated raises the question of which drugs use which carriers. Results To answer this, we have constructed a chemical genomics platform built upon the yeast gene deletion collection, using competition experiments in batch fermenters and robotic automation...

  3. Co-relation of Variables Involved in the Occurrence of Crane Accidents in U.S. through Logit Modeling

    E-Print Network [OSTI]

    Bains, Amrit Anoop Singh

    2010-10-12

    technical challenges, which has lead to escalation of danger on a construction site. Data from OSHA show that crane accidents have increased rapidly from 2000 to 2004. By analyzing the characteristics of all the crane accident inspections, we can better...

  4. The cost of public involvement lessons learned: How we can reinvest in the future

    SciTech Connect (OSTI)

    Baranski, S.C. [Equinox Environmental, Inc., Shushan, NY (United States); McMullin, K.M. [Equinox Environmental, Inc., Ballston Spa, NY (United States)

    1996-12-31

    Throughout the history of environmental remediation and restoration projects, education programs have been viewed as something to develop when the financial climate is good, and something to eliminate when the financial picture declines. Technology and risk are issues that citizens and interested community members have come to be concerned about regardless of the purpose of the project. Many times the public response to an environmental remediation effort is unanticipated. Government and industry representatives often forget that even a {open_quotes}cleanup{close_quotes} effort can cause unrest in a community. Past education and public involvement efforts have been costly, from both a financial perspective and from a public policy and programmatic perspective. Money alone cannot provide education and public involvement opportunities that will enable a project to go forward to completion. Investment in environmental programs and projects for education, public involvement and communication activities has been substantial, from a financial point of view. Investment, from a policy and program success perspective, has not yielded high returns on the investment. One must examine past and current education and public involvement {open_quotes}investments{close_quotes} and where emphasis has been place in development of the programs. In this review, the authors suggest the need to look at the level of investment from the following perspectives: (1) Financial, (2) Educational Opportunity, (3) Public Involvement Opportunity, (4) Policy and Programmatic Success, (5) Evaluation of Cost and Resulting Benefit, and (6) Reinvesting Our Financial Commitments for the Future.

  5. The Community Environmental Monitoring Program: Reducing Public Perception of Risk through Stakeholder Involvement

    SciTech Connect (OSTI)

    William T. Hartwell

    2007-05-21

    The Community Environmental Monitoring Program (CEMP) has promoted stakeholder involvement, awareness, and understanding of radiological surveillance in communities surrounding the Nevada Test Site (NTS) since 1981. It involves stakeholders in the operation, data collection, and dissemination of information obtained from a network of 29 stations across a wide area of Nevada, Utah and California. It is sponsored by the U.S. Department of Energy, National Nuclear Security Administration’s Nevada Site Office (NNSA/NSO) and administered by the Desert Research Institute (DRI) of the Nevada System of Higher Education. Integration of a near real-time communications system, a public web site, training workshops for involved stakeholders, and educational programs all help to alleviate public perception of risk of health effects from past activities conducted at the NTS.

  6. Proposed Tenaska Washington II Generation Project : Final Environmental Impact Statement. Volume 2: Public Involvement.

    SciTech Connect (OSTI)

    United States. Bonneville Power Administration.

    1994-01-01

    In regard to the proposed Tenaska Washington II Generation Project, the goal of the Bonneville Power Administration`s (BPA) Environmental Impact Statement (EIS) public involvement process is to determine the issues to be examined and pertinent analyses to be conducted and to solicit comments on the content and quality of information presented in the Draft Environmental Impact Statement (DEIS). Comments and questions are solicited from the public and government agencies during the scoping process and during the comment period and public hearing on the DEIS, to find out what is of most concern to them. The end product of the public involvement process is the Comment Report which follows in part of this volume on Public Involvement.

  7. Getting the lead out: Citizen involvement in the Williamsburg Bridge lead paint removal project

    SciTech Connect (OSTI)

    Forker, T.R.

    1997-08-01

    This paper examines the process and results of citizen involvement in developing new environmental control and compliance procedures used by the New York City Department of Transportation (NYC DOT) for lead paint removal on the Williamsburg Bridge and other structures. As a case study of the effects of public involvement in environmental decision-making, the study identifies and discusses the factors that produced failures or successes in satisfying the citizen`s concerns about health risks and the effectiveness of the selected pollution control technology.

  8. The Impact of Extent and Location of Mediastinal Lymph Node Involvement on Survival in Stage III Non-Small Cell Lung Cancer Patients Treated With Definitive Radiotherapy

    SciTech Connect (OSTI)

    Fernandes, Annemarie T.; Mitra, Nandita; Xanthopoulos, Eric; Evans, Tracey; Stevenson, James; Langer, Corey; Kucharczuk, John C.; Lin, Lilie; Rengan, Ramesh

    2012-05-01

    Purpose: Several surgical series have identified subcarinal, contralateral, and multilevel nodal involvement as predictors of poor overall survival in patients with Stage III non-small-cell lung cancer (NSCLC) treated with definitive resection. This retrospective study evaluates the impact of extent and location of mediastinal lymph node (LN) involvement on survival in patients with Stage III NSCLC treated with definitive radiotherapy. Methods and Materials: We analyzed 106 consecutive patients with T1-4 N2-3 Stage III NSCLC treated with definitive radiotherapy at University of Pennsylvania between January 2003 and February 2009. For this analysis, mediastinal LN stations were divided into four mutually exclusive groups: supraclavicular, ipsilateral mediastinum, contralateral mediastinum, and subcarinal. Patients' conditions were then analyzed according to the extent of involvement and location of mediastinal LN stations. Results: The majority (88%) of patients received sequential or concurrent chemotherapy. The median follow-up time for survivors was 32.6 months. By multivariable Cox modeling, chemotherapy use (hazard ratio [HR]: 0.21 [95% confidence interval (CI): 0.07-0.63]) was associated with improved overall survival. Increasing primary tumor [18F]-fluoro-2-deoxy-glucose avidity (HR: 1.11 [CI: 1.06-1.19]), and subcarinal involvement (HR: 2.29 [CI: 1.11-4.73]) were significant negative predictors of overall survival. On univariate analysis, contralateral nodal involvement (HR: 0.70 [CI: 0.33-1.47]), supraclavicular nodal involvement (HR: 0.78 [CI: 0.38-1.67]), multilevel nodal involvement (HR: 0.97 [CI: 0.58-1.61]), and tumor size (HR: 1.04 [CI: 0.94-1.14]) did not predict for overall survival. Patients with subcarinal involvement also had lower rates of 2-year nodal control (51.2% vs. 74.9%, p = 0.047) and 2-year distant control (28.4% vs. 61.2%, p = 0.043). Conclusions: These data suggest that the factors that determine oncologic outcome in Stage III NSCLC patients treated with definitive radiotherapy are distinct from those observed in patients who undergo surgical resection. The ultimate efficacy of radiation in locally advanced NSCLC is dependent on the intrinsic biology of the tumor.

  9. Mechanistic Studies on the Radical S-Adenosylmethionine Enzymes Involved in Molybdopterin, Thiamin and Vitamin B12 Biosynthesis 

    E-Print Network [OSTI]

    Mehta, Angad P

    2015-02-09

    ) hydroxybenzimidazole synthase, HBI synthase, involved in anaerobic vitamin B12 biosynthesis. MoaA catalyzes the first step in molydopterin biosynthesis where GTP is converted to pterin. This catalysis involves a remarkable rearrangement reaction where the C8...

  10. The EMBO Journal vol. 13 no. 1 1 pp.2592 -2599, 1994 Genetic and molecular analyses of mutations involved in

    E-Print Network [OSTI]

    Higgins, Darren

    involved in Drosophila raf signal transduction Xiangyi Lu, Michael B.Melnick, Jui-Chou Hsu and Norbert

  11. INVOLVEMENT OF THE FGFR4 Arg388 ALLELE IN HEAD AND NECK SQUAMOUS CELL CARCINOMA

    E-Print Network [OSTI]

    Ullrich, Axel

    INVOLVEMENT OF THE FGFR4 Arg388 ALLELE IN HEAD AND NECK SQUAMOUS CELL CARCINOMA Sylvia STREIT 1/Arg polymorphism (388) in head and neck squamous cell carcinomas (HNSCCs) of the oral cavity and the oropharynx and graded into a low, intermediate, or high degree of staining. FGFR4 expression was scored as high in 17

  12. Sensor applications have now touched onto the realms of real-time data processing involving

    E-Print Network [OSTI]

    Najjar, Walid A.

    sensing needs, coupled with an interface integrating up to gigabyte scale energy efficient data storage sound / voice samples. Such applications demand real time storage, filtering, frequency domain analysis involving algorithms as sophisticated as Fast Fourier Transform (FFT), Finite Impulse Response (FIR

  13. The Penrose inequality in general relativity and volume comparison theorems involving scalar curvature (thesis)

    E-Print Network [OSTI]

    Hubert L. Bray

    2009-02-18

    In this thesis we describe how minimal surface techniques can be used to prove the Penrose inequality in general relativity for two classes of 3-manifolds. We also describe how a new volume comparison theorem involving scalar curvature for 3-manifolds follows from these same techniques.

  14. Computationally efficient parabolic equation solutions to seismo-acoustic problems involving

    E-Print Network [OSTI]

    Computationally efficient parabolic equation solutions to seismo-acoustic problems involving thin converged solutions. In this paper, a seismo-acoustic parabolic equation solution is derived utilizing require finer grids to fully sample effects due to elasticity within the layer. As shear wave speeds

  15. [21] FusionBased Strategies to Identify Genes Involved in Degradation of a Specific Substrate

    E-Print Network [OSTI]

    Hampton, Randy

    [21] FusionBased Strategies to Identify Genes Involved in Degradation of a Specific Substrate By RANDOLPH Y. HAMPTON Abstract Fusion proteins have been used in many instances to allow genetic screening Principles of Using Fusion Reporters to Discover Degradation Genes Because protein degradation is highly

  16. Arabidopsis genomes uncoupled 5 (GUN5) mutant reveals the involvement of Mg-chelatase H subunit

    E-Print Network [OSTI]

    Brusslan, Judy

    Arabidopsis genomes uncoupled 5 (GUN5) mutant reveals the involvement of Mg-chelatase H subunit nuclear- and chloroplast-localized genes that encode photosynthesis-related proteins. Arabidopsis GUN (ge. Unlike wild-type plants, gun mutants have nuclear Lhcb1 expression in the absence of chloroplast

  17. Local Involvement in Measuring and Governing Carbon Stocks in China, Vietnam, Indonesia and Laos

    E-Print Network [OSTI]

    26 Local Involvement in Measuring and Governing Carbon Stocks in China, Vietnam, Indonesia and Laos-REDD+ study sites in China, Vietnam, Indonesia and Laos have been trained in establishing vegetation plots in China, Indonesia, Lao PDR and Vietnam from 2011 to 2014. ___________________________ 1 Skindergade 23

  18. Parabolic equation solution of seismo-acoustics problems involving variations in bathymetry and sediment thickness

    E-Print Network [OSTI]

    and sediment thickness Jon M. Collisa and William L. Siegmann Rensselaer Polytechnic Institute110 8th Street within elastic sediment layers. When these methods are implemented together, the parabolic equation method can be applied to problems involving variations in bathymetry and the thickness of sediment layers

  19. Response to Xanthomonas campestris pv. vesicatoria in Tomato Involves Regulation of Ethylene Receptor

    E-Print Network [OSTI]

    Klee, Harry J.

    Response to Xanthomonas campestris pv. vesicatoria in Tomato Involves Regulation of Ethylene ethylene's role in plant response to virulent and avirulent strains of Xanthomonas campestris pv overexpressing a wild-type NR cDNA were infected with virulent X. campestris pv. vesicatoria. Like the Nr mutant

  20. Emergency Action Plan For incidents involving hazardous materials, fires, explosions, or natural gas

    E-Print Network [OSTI]

    Mojzsis, Stephen J.

    -492-6025. For Non-Emergency Fire and Natural Gas Questions call the CU Fire Marshall @ 303-492-4042. AdditionalEmergency Action Plan For incidents involving hazardous materials, fires, explosions, or natural gas leaks, the following actions should be taken: 1) Life Safety First 2) Evacuate Immediate Area 3

  1. Marketing involves the design, pricing, promotion and distribution of goods and services for consumers.

    E-Print Network [OSTI]

    5/2013 MARKETING Marketing involves the design, pricing, promotion and distribution of goods marketing's critical role in analyzing consumer needs and the importance of securing information designed and services for consumers. Marketing encompasses consumer behavior, retail business site selection, store

  2. Study: Among Street-Involved Youth, Women Twice as Likely to be Infected with Hepatitis C

    E-Print Network [OSTI]

    Kavanagh, Karen L.

    Study: Among Street-Involved Youth, Women Twice as Likely to be Infected with Hepatitis C Vancouver the hepatitis C virus (HCV), according to a new study by the BC Centre for Excellence in HIV/AIDS (BC surveillance data, on a national scale, men have higher rates of hepatitis C diagnosis than women (36.8 per 100

  3. Planning for multiple mobile robots in dynamic environ ments involves determining the optimal path each robot

    E-Print Network [OSTI]

    Stentz, Tony

    Abstract Planning for multiple mobile robots in dynamic environ­ ments involves determining the optimal path each robot should follow to accomplish the goals of the mission, given the current knowledge reassign robots to goals in order to continually minimize the time to complete the mission. In this paper

  4. On the Cover: One route to harvesting the energy of the sun involves learning to mimic

    E-Print Network [OSTI]

    Wu, Zhigang

    #12;On the Cover: One route to harvesting the energy of the sun involves learning to mimic natural the chlorophylls, which play a central role in capturing light and using its energy for photosynthesis in green, and atmospheric carbon dioxide. #12;BASIC RESEARCH NEEDS FOR SOLAR ENERGY UTILIZATION Report on the Basic Energy

  5. Differing Professional Opinions Manual for Technical Issues Involving Environment, Safety, and Health

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2006-11-16

    This Manual establishes a differing professional opinion (DPO) policy to a Department of Energy (DOE) Differing Professional Opinion (DPO) Process to encourage and facilitate dialogue and resolution on DPOs from employees for technical issues involving environment, safety, and health. Does not cancel other directives. Canceled by DOE O 442.2.

  6. Quantitative traits loci (QTL) involved in body colour, wing morphometry, cuticular hydrocarbons

    E-Print Network [OSTI]

    Quantitative traits loci (QTL) involved in body colour, wing morphometry, cuticular hydrocarbons for wing morphometry, 12 for cuticular hydrocarbons and five for venom components. We detected 50 QTL / cuticular hydrocarbons / venom 1. INTRODUCTION The first genetic map built from RAPD markers (Hunt and Page

  7. Statistical Issues in the Study of Air Pollution Involving Airborne Particulate Matter

    E-Print Network [OSTI]

    Washington at Seattle, University of

    Statistical Issues in the Study of Air Pollution Involving Airborne Particulate Matter Lawrence H which provides the Center's primary funding. #12;1 STATISTICAL ISSUES IN THE STUDY OF AIR POLLUTION.S. cities. This and other scientific and policy information formed the basis on which the U.S. Environmental

  8. A ash-drag effect in random motion reveals involvement of preattentive motion processing

    E-Print Network [OSTI]

    Whitney, David

    A ash-drag effect in random motion reveals involvement of preattentive motion processing Department-ku, Tokyo, JapanIkuya Murakami The ash-drag (FDE) effect refers to the phenomenon in which the position of a stationary ashed object in one location appears shifted in the direction of nearby motion. Over the past

  9. Real and padic expansions involving symmetric patterns Boris ADAMCZEWSKI & Yann BUGEAUD

    E-Print Network [OSTI]

    Bugeaud, Yann

    , and by questions related to the expected normality of irrational algebraic numbers. We introduce a class symmetric patterns. Then, we prove several transcendence statements involving both real and p­adic numbers) expansion of irrational algebraic real (resp. p­adic) numbers. Moreover, it is expected that these numbers

  10. 3280 J. Am. Chem. Soc. 1982, 104, 3280-3287 Energetics and Mechanisms for Reactions Involving

    E-Print Network [OSTI]

    Goddard III, William A.

    is thought4 to involve several of species I-IX. In addition, thermochemical studies of I-IX provide limited thermochemical data are available. Several ab initio calculations on N2H20isomers have previously ;>N-N- 37.6 35.4 3.0 IX Table 11. Relative Enthalpies (at 298 K) Useful in AnalyzingReaction 57 NH

  11. Introduction Animals must feed to survive, but foraging often involves a

    E-Print Network [OSTI]

    Sokolowski, Marla

    from predators, parasites, exhaustion or toxins, for example. Many risk-mitigation adaptations, which., 2006). Within a species, individuals may exhibit polymorphic and/or plastic responses to fluctuating food availability. Naturally varying genes involved in plastic responses to changes in food

  12. The Case for APICS Involvement with Auto-ID Technology Edmund W. Schuster

    E-Print Network [OSTI]

    Brock, David

    members. The establishment of industry standards for the Universal Product Code (UPC) is a major reason so many organizations belong to the UCC. Though APICS is not in a position to develop industry standards of the reason traces to a historical lack of involvement from the food industry in society matters

  13. Defining and Model Checking Abstractions of Complex Railway Models using CSP||B

    E-Print Network [OSTI]

    Doran, Simon J.

    Defining and Model Checking Abstractions of Complex Railway Models using CSP||B Faron Moller1. In [11, 10] we propose a new modelling approach for railway interlockings. We use CSP||B [13], which involves events such as train movements and, in the interlocking, state based reasoning. In this sense, CSP

  14. A General Hippocampal Computational Model Combining Episodic and Spatial Memory in a Spiking Model 

    E-Print Network [OSTI]

    Aguiar, Paulo de Castro

    The hippocampus, in humans and rats, plays crucial roles in spatial tasks and nonspatial tasks involving episodic-type memory. This thesis presents a novel computational model of the hippocampus (CA1, CA3 and dentate ...

  15. RNS and Pure Spinors Equivalence for Type I Tree Level Amplitudes Involving up to Four Fermions

    E-Print Network [OSTI]

    G. Alencar; M. O. Tahim; R. R. Landim; R. N. Costa Filho

    2011-11-25

    In this paper we give a proof of the equivalence between the RNS and Pure Spinor formalism for Type I tree level amplitudes involving up to four fermions. This result have been obtained previously for amplitudes involving only closed or open amplitudes and here we extend it to include Type I amplitudes. For this we first prove the cyclic symmetry of Type I superstring in a way that it is also valid for the Pure Spinor formalism. The technique used is applied to simplify the calculation of the tree level three point amplitude previously computed. As a byproduct, we are able to calculate the gauge anomaly amplitude of type I Superstrings in this formalism.

  16. NEAMS FPL M2 Milestone Report: Development of a UO? Grain Size Model using Multicale Modeling and Simulation

    SciTech Connect (OSTI)

    Michael R Tonks; Yongfeng Zhang; Xianming Bai

    2014-06-01

    This report summarizes development work funded by the Nuclear Energy Advanced Modeling Simulation program's Fuels Product Line (FPL) to develop a mechanistic model for the average grain size in UO? fuel. The model is developed using a multiscale modeling and simulation approach involving atomistic simulations, as well as mesoscale simulations using INL's MARMOT code.

  17. Multicolor Ramsey Numbers Involving K3 + e and K4 -e

    E-Print Network [OSTI]

    Radziszowski, Stanislaw P.

    On Some Multicolor Ramsey Numbers Involving K3 + e and K4 - e Daniel S. Shetler Department: The Ramsey number R(G1, G2, G3) is the smallest positive in- teger n such that for all 3-colorings color. We study the bounds on various 3-color Ramsey numbers R(G1, G2, G3), where Gi {K3, K3 + e, K4

  18. TEC protein tyrosine kinase is involved in the Erk signaling pathway induced by HGF

    SciTech Connect (OSTI)

    Li, Feifei; Jiang, Yinan [Department of Pathophysiology, Anhui Medical University, Hefei 230032 (China)] [Department of Pathophysiology, Anhui Medical University, Hefei 230032 (China); Zheng, Qiping [Department of Anatomy and Cell Biology, Rush University Medical Center, Chicago, IL 60612 (United States)] [Department of Anatomy and Cell Biology, Rush University Medical Center, Chicago, IL 60612 (United States); Yang, Xiaoming [Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850 (China)] [Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850 (China); Wang, Siying, E-mail: sywang@ahmu.edu.cn [Department of Pathophysiology, Anhui Medical University, Hefei 230032 (China)] [Department of Pathophysiology, Anhui Medical University, Hefei 230032 (China)

    2011-01-07

    Research highlights: {yields} TEC is rapidly tyrosine-phosphorylated and activated by HGF-stimulation in vivo or after partial hepatectomy in mice. {yields} TEC enhances the activity of Elk and serum response element (SRE) in HGF signaling pathway in hepatocyte. {yields} TEC promotes hepatocyte proliferation through the Erk-MAPK pathway. -- Abstract: Background/aims: TEC, a member of the TEC family of non-receptor type protein tyrosine kinases, has recently been suggested to play a role in hepatocyte proliferation and liver regeneration. This study aims to investigate the putative mechanisms of TEC kinase regulation of hepatocyte differentiation, i.e. to explore which signaling pathway TEC is involved in, and how TEC is activated in hepatocyte after hepatectomy and hepatocyte growth factor (HGF) stimulation. Methods: We performed immunoprecipitation (IP) and immunoblotting (IB) to examine TEC tyrosine phosphorylation after partial hepatectomy in mice and HGF stimulation in WB F-344 hepatic cells. The TEC kinase activity was determined by in vitro kinase assay. Reporter gene assay, antisense oligonucleotide and TEC dominant negative mutant (TEC{sup KM}) were used to examine the possible signaling pathways in which TEC is involved. The cell proliferation rate was evaluated by {sup 3}H-TdR incorporation. Results: TEC phosphorylation and kinase activity were increased in 1 h after hepatectomy or HGF treatment. TEC enhanced the activity of Elk and serum response element (SRE). Inhibition of MEK1 suppressed TEC phosphorylation. Blocking TEC activity dramatically decreased the activation of Erk. Reduced TEC kinase activity also suppressed the proliferation of WB F-344 cells. These results suggest TEC is involved in the Ras-MAPK pathway and acts between MEK1 and Erk. Conclusions: TEC promotes hepatocyte proliferation and regeneration and is involved in HGF-induced Erk signaling pathway.

  19. Deuteron stripping and pickup involving halo nuclei 11Be and 15C

    E-Print Network [OSTI]

    A. Deltuva

    2009-04-22

    Three-body calculations of (d,p) and (p,d) reactions involving one-neutron halo nuclei 11Be and 15C are performed using the framework of Faddeev-type scattering equations. Important effects of the optical potential nonlocality are found improving the description of the experimental data. The obtained values for the neutron spectroscopic factor are consistent with estimations from other approaches.

  20. Spatial arrangement of trail markers and visitor involvement on a self-guided interpretive trail 

    E-Print Network [OSTI]

    Marcy, Julie Benedict

    1982-01-01

    be presented by asking "what constitutes an effective SGT in terms of visitor involvement with t'ne trail, leaflet suggestions, and the spacing of stakes or markers on the trail?" An effecrive program or technique is one which achieves its desired... concluded with open-ended questions on suggested improvements for the trail and leaflet. Sontag (27) states rhat there are three main ccmponents of t. rail evaluation: personal objeccive evaluation, observing visitor reaction, and questionnaires...

  1. Temperature of aircraft cargo flame exposure during accidents involving fuel spills

    SciTech Connect (OSTI)

    Mansfield, J.A.

    1993-01-01

    This report describes an evaluation of flame exposure temperatures of weapons contained in alert (parked) bombers due to accidents that involve aircraft fuel fires. The evaluation includes two types of accident, collisions into an alert aircraft by an aircraft that is on landing or take-off, and engine start accidents. Both the B-1B and B-52 alert aircraft are included in the evaluation.

  2. 35.1 Introduction Flows.involving.phase.change.are.ubiquitous.in.geophysical.and.

    E-Print Network [OSTI]

    Huppert, Herbert

    467 35.1 Introduction Flows.involving.phase.change.are.ubiquitous.in.geophysical.and. industrial.and.atmosphere.but.also.some.that.occur.in.water- saturated.soils,.in.magmatic.systems,.and.in.industrial.processes. 35.2 Principles Changes.of.phase,.from.and.associated.buoyancy.forces..The.importance.of.phase. change.to.a.given.flow.can.be.assessed.by.estimating.certain.key. dimensionless.parameters. 35

  3. Involvement of HIF-2?-mediated inflammation in arsenite-induced transformation of human bronchial epithelial cells

    SciTech Connect (OSTI)

    Xu, Yuan; Zhao, Yue; Xu, Wenchao; Luo, Fei; Wang, Bairu; Li, Yuan; Pang, Ying; Liu, Qizhan, E-mail: drqzliu@hotmail.com

    2013-10-15

    Arsenic is a well established human carcinogen that causes diseases of the lung. Some studies have suggested a link between inflammation and lung cancer; however, it is unknown if arsenite-induced inflammation causally contributes to arsenite-caused malignant transformation of cells. In this study, we investigated the molecular mechanisms underlying inflammation during neoplastic transformation induced in human bronchial epithelial (HBE) cells by chronic exposure to arsenite. The results showed that, on acute or chronic exposure to arsenite, HBE cells over-expressed the pro-inflammatory cytokines, interleukin-6 (IL-6), interleukin-8 (IL-8), and interleukin-1? (IL-1?). The data also indicated that HIF-2? was involved in arsenite-induced inflammation. Moreover, IL-6 and IL-8 were essential for the malignant progression of arsenite-transformed HBE cells. Thus, these experiments show that HIF-2? mediates arsenite-induced inflammation and that such inflammation is involved in arsenite-induced malignant transformation of HBE cells. The results provide a link between the inflammatory response and the acquisition of a malignant transformed phenotype by cells chronically exposed to arsenite and thus establish a previously unknown mechanism for arsenite-induced carcinogenesis. - Highlights: • Arsenite induces inflammation. • Arsenite-induced the increases of IL-6 and IL-8 via HIF-2?. • Inflammation is involved in arsenite-induced carcinogenesis.

  4. Quality control procedures for dynamic treatment delivery techniques involving couch motion

    SciTech Connect (OSTI)

    Yu, Victoria Y.; Fahimian, Benjamin P.; Xing, Lei; Hristov, Dimitre H.

    2014-08-15

    In this study, the authors introduce and demonstrate quality control procedures for evaluating the geometric and dosimetric fidelity of dynamic treatment delivery techniques involving treatment couch motion synchronous with gantry and multileaf collimator (MLC). Tests were designed to evaluate positional accuracy, velocity constancy and accuracy for dynamic couch motion under a realistic weight load. A test evaluating the geometric accuracy of the system in delivering treatments over complex dynamic trajectories was also devised. Custom XML scripts that control the Varian TrueBeam™ STx (Serial #3) axes in Developer Mode were written to implement the delivery sequences for the tests. Delivered dose patterns were captured with radiographic film or the electronic portal imaging device. The couch translational accuracy in dynamic treatment mode was 0.01 cm. Rotational accuracy was within 0.3°, with 0.04 cm displacement of the rotational axis. Dose intensity profiles capturing the velocity constancy and accuracy for translations and rotation exhibited standard deviation and maximum deviations below 3%. For complex delivery involving MLC and couch motions, the overall translational accuracy for reproducing programmed patterns was within 0.06 cm. The authors conclude that in Developer Mode, TrueBeam™ is capable of delivering dynamic treatment delivery techniques involving couch motion with good geometric and dosimetric fidelity.

  5. Kinetics and dynamics of oxidation reactions involving adsorbed CO species on bulk supported Pt and copper oxides. Final project report, January 1, 1991--December 31, 1993

    SciTech Connect (OSTI)

    Conner, Wm.C.; Harold, M.

    1995-02-01

    This research was an integrated experimental and modeling study of oxidation reactions involving CO as a key player - be it a reactant, adsorbed intermediate, and/or partial oxidation product - in the catalytic sequence and chemistry. The reaction systems of interest in the project include CO, formaldehyde, and methanol oxidation by O{sub 2}, and CO oxidation by NO, on both Pt and copper oxide catalysts. These reactions are of importance in automobile exhaust catalysis. There is a paucity of rate data in the literature for these important environmental control reactions. A complicating factor is the propensity of these reactions to exhibit complex steady state and dynamic behavior, including multiple rate controlling steps, steady state multiplicity, and oscillatory phenomena. Such phenomena are rooted in some of the central issues of catalysis, including adsorbate interactions, and catalyst structural instabilities, such as surface reconstruction and surface chemical changes by oxidation- reduction. The goal of this research is to better understand the catalytic chemistry and kinetics of oxidations reactions involving CO as an adsorbed intermediate. Successfully meeting this goal requires an integration of basic kinetic measurements, in situ catalyst surface monitoring, kinetic modeling, and nonlinear mathematical tools. While the kinetics experiments have standard microreactor design, the potential for multiple and periodic rate states demands detailed procedures to pinpoint the bifurcation (ignition, extinction, Hopf) points. Kinetic models are constructed from rational mechanistic sequences and sound surface chemistry.

  6. Computationally Efficient Model for Dopant Precipitation Kinetics

    E-Print Network [OSTI]

    Dunham, Scott

    Computationally Efficient Model for Dopant Precipitation Kinetics Iuval Clejan and Scott T. Dunham and precipitates. Dopant deactivation is typically modeled using a steady­state solid solubility or clustering such as dopant activation/deactivation, it is essential to consider the fact that precipitation involves a range

  7. Investigation of Skin Tribology and Its Effects on Coefficient of Friction and Other Tactile Attributes Involving Polymer Applications 

    E-Print Network [OSTI]

    Darden, Matthew Aguirre

    2012-02-14

    OF SKIN TRIBOLOGY AND ITS EFFECTS ON COEFFICIENT OF FRICTION AND OTHER TACTILE ATTRIBUTES INVOLVING POLYMER APPLICATIONS A Thesis by MATTHEW AGUIRRE DARDEN Submitted to the Office of Graduate Studies of Texas A&M University in partial... Tactile Attributes Involving Polymer Applications Copyright 2010 Matthew Aguirre Darden INVESTIGATION OF SKIN TRIBOLOGY AND ITS EFFECTS ON COEFFICIENT OF FRICTION AND OTHER TACTILE ATTRIBUTES INVOLVING POLYMER APPLICATIONS A Thesis...

  8. Report on International Collaboration Involving the FE Heater and HG-A Tests at Mont Terri

    E-Print Network [OSTI]

    Houseworth, Jim

    2014-01-01

    BBM Barcelona Basic Model CIEMAT Centro de Investigacionesdesign (Nater, 2012). 2) CIEMAT and UPC of Spain conductedmodel as applied by the CIEMAT and UPC (Garitte and Gens,

  9. THE RELATIONSHIP BETWEEN HIGH INVOLVEMENT WORK SYSTEMS, SUPERVISORY SUPPORT, AND ORGANIZATIONAL EFFECTIVENESS: THE ROLE OF EMPLOYEE EXPERIENCES AT WORK

    E-Print Network [OSTI]

    Wadhwa, Preeti

    2012-08-31

    This study adopts a multilevel, multiple stakeholder perspective to examine the impact of high involvement work systems (HIWS) and supervisory support on organizational effectiveness. Organizational effectiveness is measured ...

  10. Identification and Characterization of Soluble Factors Involved in Delayed Effects of Low Dose Radiation. Final report

    SciTech Connect (OSTI)

    Baulch, Janet

    2013-09-11

    This is a 'glue grant' that was part of a DOE Low Dose project entitled 'Identification and Characterization of Soluble Factors Involved in Delayed Effects of Low Dose Radiation'. This collaborative program has involved Drs. David L. Springer from Pacific Northwest National Laboratory (PNNL), John H. Miller from Washington State University, Tri-cities (WSU) and William F. Morgan then from the University of Maryland, Baltimore (UMB). In July 2008, Dr. Morgan moved to PNNL and Dr. Janet E. Baulch became PI for this project at University of Maryland. In November of 2008, a one year extension with no new funds was requested to complete the proteomic analyses. The project stemmed from studies in the Morgan laboratory demonstrating that genomically unstable cells secret a soluble factor or factors into the culture medium, that cause cytogenetic aberrations and apoptosis in normal parental GM10115 cells. The purpose of this project was to identify the death inducing effect (DIE) factor or factors, estimate their relative abundance, identify the cell signaling pathways involved and finally recapitulate DIE in normal cells by exogenous manipulation of putative DIE factors in culture medium. As reported in detail in the previous progress report, analysis of culture medium from the parental cell line, and stable and unstable clones demonstrated inconsistent proteomic profiles as relate to candidate DIE factors. While the proposed proteomic analyses did not provide information that would allow DIE factors to be identified, the analyses provided another important set of observations. Proteomic analysis suggested that proteins associated with the cellular response to oxidative stress and mitochondrial function were elevated in the medium from unstable clones in a manner consistent with mitochondrial dysfunction. These findings correlate with previous studies of these clones that demonstrated functional differences between the mitochondria of stable and unstable clones. These mitochondrial abnormalities in the unstable clones contributes to oxidative stress.

  11. LOFAR-UK White Paper: A Science case for UK involvement in LOFAR

    E-Print Network [OSTI]

    P. N. Best; the LOFAR-UK Consortium

    2008-02-08

    LOFAR, the Low-Frequency Array, is a next-generation software-driven radio telescope operating between 30 and 240MHz, currently under construction by ASTRON in the Netherlands. This low frequency radio band is one of the few largely unexplored regions of the electromagnetic spectrum. The sensitivity and angular resolution offered by LOFAR will be two to three orders of magnitude better than existing telescopes, and as such it will open up this new window on the Universe. LOFAR will impact on a broad range of astrophysics, from cosmology to solar system studies. There is growing European involvement in LOFAR, driven by the need to add stations far from the main core in order to improve angular resolution. LOFAR-UK is a project aimed at cementing UK participation in LOFAR via the operation of four stations within the UK. LOFAR-UK ground stations will allow LOFAR observations to reach sub-arcsecond scales at the highest frequencies, and as a result will also improve the (confusion-limited) sensitivity limit of the telescope for deep surveys. LOFAR-UK will achieve involvement for UK astronomers in a world-leading science facility operating in the immediate future. It will allow the UK to build up important scientific and technical expertise in `next generation' radio astronomy in preparation for the Square Kilometre Array (SKA), and will play an important role in broadening the UK community that has an interest in radio astronomy. This White Paper outlines the strategic importance to the UK astronomy community of gaining involvement in the LOFAR project, the scientific interests of UK researchers in using the telescope, and the technical challenges that will need to be overcome [abridged].

  12. Fatal accidents involving roof falls in coal mining, 1996--1998

    SciTech Connect (OSTI)

    Not Available

    1999-01-01

    This publication presents information on fatalities involving roof and rib falls that occurred in coal mining operations from January 1996 through December 1998. It includes statistics for the fatalities, as well as abstracts, best practices and illustrations. Conclusion statements have been substituted for best practices where no Title 30 Code of Regulations violations were cited during the accident investigation. From January 1996 through December 1998, 36 miners died at coal operations from accidents classified as roof falls. The information in the report is based on statistics taken from the 1996 through 1998 MSHA Fatal Illustration Programs: Roof Fall Fatalities by District.

  13. Fatal accidents involving roof falls in coal mining, 1996--1998

    SciTech Connect (OSTI)

    NONE

    1999-11-01

    This publication presents information on fatalities involving roof and rib falls that occurred in coal mining operations from January 1996 through December 1998. It includes statistics for the fatalities, as well as abstracts, best practices and illustrations. Conclusion statements have been substituted for best practices where no Title 30 Code of Regulations violations were cited during the accident investigation. From January 1996 through December 1998, 36 miners died at coal operations from accidents classified as roof falls. The information in the report is based on statistics taken from the 1996 through 1998 MSHA Fatal Illustration Programs: Roof Fall Fatalities by District.

  14. Use of Science in Gulf of Mexico Decision Making Involving Climate Change 

    E-Print Network [OSTI]

    Vedlitz, Arnold; Alston, Letitia T.; Laska, Shirley B.; Gramling, Robert B.; Harwell, Mark A.; Worthen, Helen D.

    2007-01-01

    Decision Making Involving Climate Change EPA COOPERATIVE AGREEMENT: R?83023601?0 September 2002 ? December 2007 Dr. ArnolD VeDlitz, Director & BoB Bullock chAir in GoVernment AnD PuBlic Policy institute for science, technoloGy AnD PuBlic Policy... Policy ? The Bush School ? Texas A&M University i Acknowledgements Research Support This material is based upon research supported by the U.S. Environmental Protection Agency's National Center for Environmental Assessment/Global Change Research...

  15. Involvement of ERK in NMDA receptor-independent cortical neurotoxicity of hydrogen sulfide

    SciTech Connect (OSTI)

    Kurokawa, Yuko; Sekiguchi, Fumiko; Kubo, Satoko; Yamasaki, Yoshiko; Matsuda, Sachi; Okamoto, Yukari; Sekimoto, Teruki; Fukatsu, Anna; Nishikawa, Hiroyuki [Division of Pharmacology and Pathophysiology, Kinki University School of Pharmacy, 3-4-1 Kowakae, Higashi-Osaka 577-8502 (Japan)] [Division of Pharmacology and Pathophysiology, Kinki University School of Pharmacy, 3-4-1 Kowakae, Higashi-Osaka 577-8502 (Japan); Kume, Toshiaki [Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-shimoadachi-cho, Sakyo-ku, Kyoto 606-8501 (Japan)] [Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-shimoadachi-cho, Sakyo-ku, Kyoto 606-8501 (Japan); Fukushima, Nobuyuki [Division of Molecular Neurobiology, Department of Life Sciences, Kinki University School of Science and Engineering, 3-4-1 Kowakae, Higashi-Osaka 577-8502 (Japan)] [Division of Molecular Neurobiology, Department of Life Sciences, Kinki University School of Science and Engineering, 3-4-1 Kowakae, Higashi-Osaka 577-8502 (Japan); Akaike, Akinori [Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-shimoadachi-cho, Sakyo-ku, Kyoto 606-8501 (Japan)] [Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-shimoadachi-cho, Sakyo-ku, Kyoto 606-8501 (Japan); Kawabata, Atsufumi, E-mail: kawabata@phar.kindai.ac.jp [Division of Pharmacology and Pathophysiology, Kinki University School of Pharmacy, 3-4-1 Kowakae, Higashi-Osaka 577-8502 (Japan)] [Division of Pharmacology and Pathophysiology, Kinki University School of Pharmacy, 3-4-1 Kowakae, Higashi-Osaka 577-8502 (Japan)

    2011-11-04

    Highlights: Black-Right-Pointing-Pointer Hydrogen sulfide causes NMDA receptor-independent neurotoxicity in mouse fetal cortical neurons. Black-Right-Pointing-Pointer Activation of ERK mediates the toxicity of hydrogen sulfide. Black-Right-Pointing-Pointer Apoptotic mechanisms are involved in the hydrogen-induced cell death. -- Abstract: Hydrogen sulfide (H{sub 2}S), a gasotransmitter, exerts both neurotoxicity and neuroprotection, and targets multiple molecules including NMDA receptors, T-type calcium channels and NO synthase (NOS) that might affect neuronal viability. Here, we determined and characterized effects of NaHS, an H{sub 2}S donor, on cell viability in the primary cultures of mouse fetal cortical neurons. NaHS caused neuronal death, as assessed by LDH release and trypan blue staining, but did not significantly reduce the glutamate toxicity. The neurotoxicity of NaHS was resistant to inhibitors of NMDA receptors, T-type calcium channels and NOS, and was blocked by inhibitors of MEK, but not JNK, p38 MAP kinase, PKC and Src. NaHS caused prompt phosphorylation of ERK and upregulation of Bad, followed by translocation of Bax to mitochondria and release of mitochondrial cytochrome c, leading to the nuclear condensation/fragmentation. These effects of NaHS were suppressed by the MEK inhibitor. Our data suggest that the NMDA receptor-independent neurotoxicity of H{sub 2}S involves activation of the MEK/ERK pathway and some apoptotic mechanisms.

  16. Towards a Model of the Costs of Security David Larochelle

    E-Print Network [OSTI]

    Huang, Wei

    areas, in information security there is no free lunch. The process of system design involves trade technical advances. In our model, the software design process involves trade-offs between security, there is an implicit trade-off between security and functionality. We refer to the set of points that represent

  17. Comparison of isotopic transmutation modelling codes 

    E-Print Network [OSTI]

    Beard, Carl Allen

    1990-01-01

    test case involved modelling a fission pulse, while the second concerned the modelling of a long irradiation period. CINDER-10 was found to utilize an analytically based solution scheme allowing it to correctly model nearly all possible nuclear... Contribution of Fission Products to Total Decay Heat at a Cooling Time of 10 Seconds Due to a Fission Pulse . . . . . . . . . . . 30 Contribution of Fission Products tg Total Decay Heat at a Cooling Time of 10 Seconds Due to a Fission Pulse 31 III...

  18. To examine how the dynamics of recall processes are affected by the control processes involved with search termination, to study

    E-Print Network [OSTI]

    Dougherty, Michael

    involved with search termination, to study the implications of these control processes for the development at understanding the metacognitive control processes involved with the decision to terminate memory search. Specifically, research examines the impact of search termination decisions on the natural retrieval dynamics

  19. Nano-Electro-Mechanical (NEM) Relay Devices and Technology for Ultra-Low Energy Digital Integrated Circuits

    E-Print Network [OSTI]

    Nathanael, Rhesa

    2012-01-01

    Alon, and T. -J. K. Liu, "Mechanical computing redux: Relaysof integrated micro-electro-mechanical (MEM) switch circuitsof integrated micro-electro-mechanical (MEM) switch circuits

  20. Supercomputer Piz Daint, so genannt nach ei-nem Berg in Val Mstair im Graubnden, hat bei

    E-Print Network [OSTI]

    Peak Performance 7.787 Petaflops Memory Capacity per node 32 GB (DDR3-1600); 6 GB non-ECC GDDR5 Memory Bandwidth per node 51.2 GB/s DDR3 ; 250.0 GB/s non-ECC GDDR5 Total System Memory 169 TB DDR3; 32 TB non

  1. Nano-Electro-Mechanical (NEM) Relay Devices and Technology for Ultra-Low Energy Digital Integrated Circuits

    E-Print Network [OSTI]

    Nathanael, Rhesa

    2012-01-01

    designing circuits using relays. Test chips were fabricatedwith the test setup cooled with liquid nitrogen show relaystests [15]. Unfortunately, it is not practical to keep testing the relay

  2. Prozodi?ne možnosti v slovenskem knjižnem jeziku in slovenskih nare?jih

    E-Print Network [OSTI]

    Greenberg, Marc L.

    1987-01-01

    :ša), vklju?no z novimi akuti iz umikov (gl. spodaj), npr. že:na (knj. zè:na). Naglas na kra?ini je ostal in dolgi nosilec c i r k u m f l e k s a j e p o s t a l k r a t e k , n p r . 'krœx ( k n j . 'krux), 'nu? ( k n j . no:?). 'vidim ( k n j . vhditn), nu...

  3. Nano-Electro-Mechanical (NEM) Relay Devices and Technology for Ultra-Low Energy Digital Integrated Circuits

    E-Print Network [OSTI]

    Nathanael, Rhesa

    2012-01-01

    Low temperature atomic layer deposition of titania thin2 O 3 deposited by atomic layer deposition (ALD) was used asSUNALE R150 Atomic Layer Deposition (ALD) tool provided the

  4. Nano-Electro-Mechanical (NEM) Relay Devices and Technology for Ultra-Low Energy Digital Integrated Circuits

    E-Print Network [OSTI]

    Nathanael, Rhesa

    2012-01-01

    II,” Journal of Microelectromechanical Systems, vol. 12, no.Journal of Microelectromechanical Systems, vol. 6, no. 2,Journal of Microelectromechanical Systems, vol. 16, no. 1,

  5. Nano-Electro-Mechanical (NEM) Relay Devices and Technology for Ultra-Low Energy Digital Integrated Circuits

    E-Print Network [OSTI]

    Nathanael, Rhesa

    2012-01-01

    II,” Journal of Microelectromechanical Systems, vol. 12, no.structures,” Journal of Microelectromechanical Systems, vol.Journal of Microelectromechanical Systems, vol. 16, no. 1,

  6. 1018 JOURNAL OF MICROELECTROMECHANICAL SYSTEMS, VOL. 13, NO. 6, DECEMBER 2004 Limit Cycle Oscillations in CW Laser-Driven NEMS

    E-Print Network [OSTI]

    Rand, Richard H.

    method (FEM), laser drive, limit cycle oscillation, self-oscillation, thermal stress. I. INTRODUCTION1018 JOURNAL OF MICROELECTROMECHANICAL SYSTEMS, VOL. 13, NO. 6, DECEMBER 2004 Limit Cycle, Richard Rand, Alan Zehnder, Jeevak Parpia, and Harold Craighead, Member, IEEE Abstract--Limit cycle

  7. Closure models for turbulent reacting flows

    SciTech Connect (OSTI)

    Dutta, A.; Tarbell, J.M. (Pennsylvania State Univ., University Park, PA (USA). Dept. of Chemical Engineering)

    1989-12-01

    In this paper, a simple procedure based on fast and slow reaction asymptotics has been employed to drive first-order closure models for the nonlinear reaction terms in turbulent mass balances from mechanistic models of turbulent mixing and reaction. The coalescence-redispersion (CRD) model, the interaction by exchange with the mean (IEM) model, the three-environment (3E) model, and the four-environment (4E) model have been used to develop closure equations. The closure models have been tested extensively against experimental data for both single and multiple reactions. The closures based on slow asymptotics for the CRD, 3E and 4E models provide very good predictions of all of the experimental data, while other models available either in the literature or derived here are not adequate. The simple new closure equations developed in this paper may be useful in modeling systems involving turbulent mixing and complex chemical reactions.

  8. Machining dynamics and stability analysis in longitudinal turning involving workpiece whirling 

    E-Print Network [OSTI]

    Dassanayake, Achala Viomy

    2009-06-02

    Tool chatter in longitudinal turning is addressed with a new perspective using a complex machining model describing the coupled tool-workpiece dynamics subject to nonlinear regenerative cutting forces, instantaneous depth-of-cut (DOC) and workpiece...

  9. Physical Simulation of an Embedded Surface Mesh Involving Deformation and Fracture 

    E-Print Network [OSTI]

    Clack, Billy

    2012-07-16

    Simulating virtual objects which can deform or break apart within their environments is now common in state-of-the-art virtual simulations such as video games or surgery simulations. Real-time performance requires a physical model which provides...

  10. NRF2 activation is involved in ozonated human serum upregulation of HO-1 in endothelial cells

    SciTech Connect (OSTI)

    Pecorelli, Alessandra [Department of Molecular and Developmental Medicine, University of Siena (Italy); Child Neuropsychiatry Unit, University Hospital, AOUS, Siena (Italy); Bocci, Velio [Department of Physiology, University of Siena (Italy); Acquaviva, Alessandra [Department of Molecular and Developmental Medicine, University of Siena (Italy); Belmonte, Giuseppe [Department of Biomedical Sciences, University of Siena (Italy); Gardi, Concetta [Department of Molecular and Developmental Medicine, University of Siena (Italy); Virgili, Fabio [INRAN, Rome (Italy); Ciccoli, Lucia [Department of Molecular and Developmental Medicine, University of Siena (Italy); Valacchi, Giuseppe, E-mail: giuseppe.valacchi@unife.it [Department of Life Sciences and Biotechnology, University of Ferrara (Italy); Department of Food and Nutrition, Kyung Hee University, Seoul (Korea, Republic of)

    2013-02-15

    During the last decade, it has been shown that the activation of NRF2 and the binding to electrophile-responsive element (EpREs), stimulates the expression of a great number of genes responsible for the synthesis of phase I and phase II proteins, including antioxidants enzymes and heme oxygenase-1 (HO-1). This critical cell response occurs in cardiovascular, degenerative and chronic infective diseases aggravated by a chronic oxidative stress. In our previous reports we have shown that ozonated plasma is able to up-regulate HO-1 expression in endothelial cells. In the present work we investigated a candidate mechanism involved in this process. After treatment with increasing doses of ozonated serum (20, 40 and 80 ?g/mL O{sub 3} per mL of serum), a clear dose dependent activation of NRF2 and the subsequent induction of HO-1 and NAD(P)H quinone oxidoreductase 1(NQO1) was observed. This effect was also present when cells were treated with serum and hydrogen peroxide (H{sub 2}O{sub 2}) or serum and 4-hydroxynonenal (4HNE). Moreover, the treatment with ozonated serum was associated with a dose-dependent activation of extracellular-signal-regulated kinases (ERK1/2) and p38 MAP kinases (p38), not directly involved in NRF2 activation. These data, provide a new insight on the mechanism responsible for the induction of HO-1 expression by ozonated serum in the endothelium, and have a practical importance as an expedient approach to the treatment of patients with both effective orthodox drugs and ozonated autohemotherapy, targeted to the restoration of redox homeostasis. - Highlights: ? Endothelial HO1 is upregulated by ozonated plasma ? This activation is induced by NRF2 and it is ERK independent. ? 4HNE and H{sub 2}O{sub 2} are the main molecules involved in this process. ? Ozonated plasma induced a hormetic effect ? Combination of orthodox medicine and ozonated plasma can be a useful treatment.

  11. Uncertainty assessment of complex models with application to aviation environmental systems

    E-Print Network [OSTI]

    Allaire, Douglas L

    2009-01-01

    Numerical simulation models that support decision-making and policy-making processes are often complex, involving many disciplines, and long computation times. These models typically have many factors of different character, ...

  12. Kinetic model for nitric oxide formation during pulverized coal combustion

    SciTech Connect (OSTI)

    Mitchell, J.W.; Tarbell, J.M.

    1982-03-01

    A mathematical model of NO formation during pulverised coal combustion was developed from a proposed kinetic mechanism involving 12 overall chemical reactions. Most significantly, the model describes the complex conversion of coal bound nitrogen compounds to NO during combustion. The predictions of the model compare favourably with literature data and are in qualitative agreement with trends observed in practical coal combustion.

  13. Dynamical systems modeling of Continuous Flash Suppression Daisuke Shimaoka

    E-Print Network [OSTI]

    Kaneko, Kunihiko

    : Binocular rivalry Adaptation Neural modeling a b s t r a c t Continuous Flash Suppression (CFS is considered to be involved in CFS, but does not reproduce CFS. We then extend the model by including of visibility observed in CFS. In addition, this model captured some defining characteristics of CFS

  14. Astrophysical S-factors for fusion reactions involving C, O, Ne and Mg isotopes

    E-Print Network [OSTI]

    M. Beard; A. V. Afanasjev; L. C. Chamon; L. R. Gasques; M. Wiescher; D. G. Yakovlev

    2010-02-03

    Using the Sao Paulo potential and the barrier penetration formalism we have calculated the astrophysical factor S(E) for 946 fusion reactions involving stable and neutron-rich isotopes of C, O, Ne, and Mg for center-of-mass energies E varying from 2 MeV to 18-30 MeV (covering the range below and above the Coulomb barrier). We have parameterized the energy dependence S(E) by an accurate universal 9-parameter analytic expression and present tables of fit parameters for all the reactions. We also discuss the reduced 3-parameter version of our fit which is highly accurate at energies below the Coulomb barrier, and outline the procedure for calculating the reaction rates. The results can be easily converted to thermonuclear or pycnonuclear reaction rates to simulate various nuclear burning phenomena, in particular, stellar burning at high temperatures and nucleosynthesis in high density environments.

  15. The Orosomucoid 1 protein is involved in the vitamin D – mediated macrophage de-activation process

    SciTech Connect (OSTI)

    Gemelli, Claudia, E-mail: claudia.gemelli@unimore.it [Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 287, 41125 Modena (Italy); Center for Regenerative Medicine, University of Modena and Reggio Emilia, Via Gottardi 100, 41125 Modena (Italy); Martello, Andrea; Montanari, Monica; Zanocco Marani, Tommaso; Salsi, Valentina; Zappavigna, Vincenzo; Parenti, Sandra; Vignudelli, Tatiana; Selmi, Tommaso; Ferrari, Sergio; Grande, Alexis [Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 287, 41125 Modena (Italy)

    2013-12-10

    Orosomucoid 1 (ORM1), also named Alpha 1 acid glycoprotein A (AGP-A), is an abundant plasma protein characterized by anti-inflammatory and immune-modulating properties. The present study was designed to identify a possible correlation between ORM1 and Vitamin D3 (1,25(OH)2D3), a hormone exerting a widespread effect on cell proliferation, differentiation and regulation of the immune system. In particular, the data described here indicated that ORM1 is a 1,25(OH)2D3 primary response gene, characterized by the presence of a VDRE element inside the 1 kb sequence of its proximal promoter region. This finding was demonstrated with gene expression studies, Chromatin Immunoprecipitation and luciferase transactivation experiments and confirmed by VDR full length and dominant negative over-expression. In addition, several experiments carried out in human normal monocytes demonstrated that the 1,25(OH)2D3 – VDR – ORM1 pathway plays a functional role inside the macrophage de-activation process and that ORM1 may be considered as a signaling molecule involved in the maintenance of tissue homeostasis and remodeling. - Highlights: • ORM1 is a Vitamin D primary response gene. • VD and its receptor VDR are involved in the de-activation process mediated by human resident macrophages. • The signaling pathway VD-VDR-ORM1 plays an important role in the control of macrophage de-activation process. • ORM1 may be defined as a signaling molecule implicated in the maintenance of tissue homeostasis and remodeling.

  16. Musashi2 modulates K562 leukemic cell proliferation and apoptosis involving the MAPK pathway

    SciTech Connect (OSTI)

    Zhang, Huijuan; Tan, Shi; Wang, Juan; Chen, Shana; Quan, Jing; Xian, Jingrong; Zhang, Shuai shuai; He, Jingang; Zhang, Ling, E-mail: lingzhang@cqmu.edu.cn

    2014-01-01

    The RNA-binding protein Musashi2 (Msi2) has been identified as a master regulator within a variety of stem cell populations via the regulation of translational gene expression. A recent study has suggested that Msi2 is strongly expressed in leukemic cells of acute myeloid leukemia patients, and elevated Msi2 is associated with poor prognosis. However, the potential role of Msi2 in leukemogenesis is still not well understood. Here, we investigated the effect of Msi2 knockdown on the biological properties of leukemic cells. High expression of Msi2 was found in K562 and KG-1a leukemic cell lines, and low expression was observed in the U937 cell line. We transduced K562 cells with two independent adenoviral shRNA vectors targeting Msi2 and confirmed knockdown of Msi2 at the mRNA and protein levels. Msi2 silencing inhibited cell growth and caused cell cycle arrest by increasing the expression of p21 and decreasing the expression of cyclin D1 and cdk2. In addition, knockdown of Msi2 promoted cellular apoptosis via the upregulation of Bax and downregulation of Bcl-2 expression. Furthermore, Msi2 knockdown resulted in the inactivation of the ERK/MAPK and p38/MAPK pathways, but no remarkable change in p-AKT was observed. These data provide evidence that Msi2 plays an important role in leukemogenesis involving the MAPK signaling pathway, which indicates that Msi2 may be a novel target for leukemia treatment. - Highlights: • Knockdown of Msi2 inhibited K562 cell growth and arrested cell cycle progression. • Knockdown of Msi2 induced K562 cell apoptosis via the regulation of Bax and Bcl-2. • The MAPK pathway was involved in the process of Msi2-mediated leukemogenesis. • Our data indicate that Msi2 is a potential new target for leukemia treatment.

  17. Modeling Chemical Reactions with Single Reactant Specie Abhyudai Singh and Jo~ao Pedro Hespanha

    E-Print Network [OSTI]

    Hespanha, João Pedro

    Modeling Chemical Reactions with Single Reactant Specie Abhyudai Singh and Jo~ao Pedro Hespanha Abstract-- A procedure for constructing approximate stochastic models for chemical reactions involving involved in a chemical reaction as the continuous state of a polynomial Stochastic Hybrid System (p

  18. Using Linear Genetic Programming to Develop a C/C++ Simulation Model of a Waste Incinerator. Larry M Deschaine PE

    E-Print Network [OSTI]

    Fernandez, Thomas

    /C++ computer simulation model that mimics the performance of the concentrations of carbon dioxide. It #12;involves variable input material properties (solids, liquids and gaseous), high temperature, large

  19. Localized customized mortality prediction modeling for patients with acute kidney injury admitted to the intensive care unit

    E-Print Network [OSTI]

    Celi, Leo Anthony G

    2009-01-01

    Introduction. Models for mortality prediction are traditionally developed from prospective multi-center observational studies involving a heterogeneous group of patients to optimize external validity. We hypothesize that ...

  20. Lifecycle Model

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    1997-05-21

    This chapter describes the lifecycle model used for the Departmental software engineering methodology.

  1. Optimal Design for Problems Involving Flow and Transport Phenomena in Saturated

    E-Print Network [OSTI]

    of injection wells p set of model parameters q Darcy velocity, or volumetric ux p uid pressure q y ; q z maximum injection rate Q T total net pumping rate rate Q e T total extraction rate Q max T maximum total

  2. Responses of Magnocellular Neurons to Osmotic Stimulation Involves Coactivation of Excitatory and Inhibitory Input: An

    E-Print Network [OSTI]

    Feng, Jianfeng

    of normal rats respond to intra- venous infusions of hypertonic saline with gradual, linear in- creases response to such infusions. We show that a simple computational model can reproduce these responses well, but only if it is assumed that hypertonic infusions coacti- vate excitatory and inhibitory synaptic inputs

  3. Exploring the Behavioral and Psychological Differences between Male and Female Youth with a History of Fire Involvement

    E-Print Network [OSTI]

    Morris, Ed M.

    2014-08-31

    Study objectives were to explore a sample of fire-involved youth by 1) describing their overall psychological characteristics, thoughts, and behaviors, 2) comparing the psychological characteristics, thoughts, and behaviors of their male and female...

  4. 6/6/2014 1 of 6 OHS 11-033 revision Animal Research Protocols Involving Hazardous Chemicals

    E-Print Network [OSTI]

    Kay, Mark A.

    OHS 11-033 revision Animal Research Protocols Involving Hazardous Chemicals I. OVERVIEW Hazardous Chemicals: Known or suspect carcinogens, reproductive toxins or other highly toxic substances (e. Reference the SU Chemical Hygiene Plan for hazardous chemical definitions. Potential Exposures: Research

  5. An Exploration of How Involvement in a Freshman Retention Program Relates to Intention to Complete an Undergraduate Degree

    E-Print Network [OSTI]

    Clounch, Teresa Lynn

    2010-07-15

    The study examined the relationship of the level and type of involvement of freshman students in the Hawk Link Retention Program, a first-year program at the University of Kansas, to intent to return and graduate. The study ...

  6. Vitellogenin Receptor and Neuropeptide Receptors Involved in Reproduction of the Red Imported Fire Ant (Solenopsis invicta Buren) 

    E-Print Network [OSTI]

    Lu, Hsiao Ling

    2012-02-14

    Social insects have complex forms of social organization. Molecular mechanisms involved in the regulation of their reproduction are not fully understood. This dissertation investigated the vitellogenin receptor (VgR), ...

  7. Community Involvement in the Preservation of World Heritage Sites: The Case of the Ukrainian Carpathian Wooden Churches 

    E-Print Network [OSTI]

    Schneider, Hans Rainer

    2013-05-30

    Encouraging the participation of the local population in the preservation of World Heritage Sites is one of the mission’s of UNESCO’s World Heritage Centre. Community involvement is also critical in the planning process. ...

  8. Involvement of voltage-sensitive calcium ion channels in release of luteinizing hormone-releasing hormone from the bovine infundibulum 

    E-Print Network [OSTI]

    Dippel, Wendy Wrae

    1993-01-01

    Bovine infundibular explants (INFE) were cultured to confirm calcium (Ca.) and voltage-sensitive calcium channel (VSCC) involvement in luteinizing hormone-releasing hormone (LHRH) release. Mid-sagitally sectioned INFE, randomly assigned to control...

  9. Endovascular Treatment of Infrarenal Abdominal Aortic Lesions With or Without Common Iliac Artery Involvement

    SciTech Connect (OSTI)

    Oender, Hakan; Oguzkurt, Levent; Guer, Serkan; Tekbas, Gueven; Guerel, Kamil; Coskun, Isa; Oezkan, Ugur

    2013-02-15

    To evaluate the results of stent placement for obstructive atherosclerotic aortic disease with or without involvement of the common iliac artery. Forty patients had self-expanding stents primarily or after balloon dilatation in the abdominal aorta between January 2005 and May 2011. All patients had trouble walking. Follow-up examinations were performed with clinical visits; these included color Doppler ultrasonography and computed tomographic angiography. Technical, clinical, and hemodynamic success was achieved in all patients. None of the patients underwent reintervention during the follow-up period, which ranged from 3 months to 6 years (median 24 months). Nine complications occurred in six patients. Of the nine complications, four were distal thromboembolisms, which were successfully treated with catheter-directed thrombolysis or anticoagulation therapy. Endovascular treatment of the obstructive aortic disease using self-expanding stents was safe and effective, with high technical success and long-term patency. Thromboembolic complications were high even though direct stenting was considered protective for thromboembolism formation. Particularly for infrarenal aortic stenosis, it can be recommended as the first-line treatment option for patients with obstructive atherosclerotic aortic disease.

  10. Risk of Developing Cardiovascular Disease After Involved Node Radiotherapy Versus Mantle Field for Hodgkin Lymphoma

    SciTech Connect (OSTI)

    Maraldo, Maja V., E-mail: dra.maraldo@gmail.com [Department of Radiation Oncology, Rigshospitalet, Copenhagen (Denmark); Brodin, Nils Patrik; Vogelius, Ivan R.; Aznar, Marianne C.; Munck af Rosenschoeld, Per; Petersen, Peter M. [Department of Radiation Oncology, Rigshospitalet, Copenhagen (Denmark); Specht, Lena [Department of Radiation Oncology, Rigshospitalet, Copenhagen (Denmark); Faculty of Health Sciences, University of Copenhagen, Copenhagen (Denmark)

    2012-07-15

    Purpose: Hodgkin lymphoma (HL) survivors are known to have increased cardiac mortality and morbidity. The risk of developing cardiovascular disease after involved node radiotherapy (INRT) is currently unresolved, inasmuch as present clinical data are derived from patients treated with the outdated mantle field (MF) technique. Methods and Materials: We included all adolescents and young adults with supradiaphragmatic, clinical Stage I-II HL treated at our institution from 2006 to 2010 (29 patients). All patients were treated with chemotherapy and INRT to 30 to 36 Gy. We then simulated a MF plan for each patient with a prescribed dose of 36 Gy. A logistic dose-response curve for the 25-year absolute excess risk of cardiovascular disease was derived and applied to each patient using the individual dose-volume histograms. Results: The mean doses to the heart, four heart valves, and coronary arteries were significantly lower for INRT than for MF treatment. However, the range in doses with INRT treatment was substantial, and for a subgroup of patients, with lymphoma below the fourth thoracic vertebrae, we estimated a 25-year absolute excess risk of any cardiac event of as much as 5.1%. Conclusions: Our study demonstrates a potential for individualizing treatment by selecting the patients for whom INRT provides sufficient cardiac protection for current technology; and a subgroup of patients, who still receive high cardiac doses, who would benefit from more advanced radiation technique.

  11. Identification of a Xylogalacturonan Xylosyltransferase Involved in Pectin Biosynthesis in Arabidopsis

    SciTech Connect (OSTI)

    Pauly, Markus; Sorensen, Susanne Oxenboll; Harholt, Jesper; Geshi, Naomi; Sakuragi, Yumiko; Moller, Isabel; Zandleven, Joris; Bernal, Adriana J.; Jensen, Niels Bjerg; Sorensen, Charlotte; Jensen, Jacob K.; Beldman, Gerrit; Willats, William G.T.; Scheller, Henrik

    2009-08-19

    Xylogalacturonan (XGA) is a class of pectic polysaccharide found in plant cell walls. The Arabidopsis thaliana locus At5g33290 encodes a predicted Type II membrane protein, and insertion mutants of the At5g33290 locus had decreased cell wall xylose. Immunological studies, enzymatic extraction of polysaccharides, monosaccharide linkage analysis, and oligosaccharide mass profiling were employed to identify the affected cell wall polymer. Pectic XGA was reduced to much lower levels in mutant than in wild-type leaves, indicating a role of At5g33290 in XGA biosynthesis. The mutated gene was designated xylogalacturonan deficient1 (xgd1). Transformation of the xgd1-1 mutant with the wild-type gene restored XGA to wild-type levels. XGD1 protein heterologously expressed in Nicotiana benthamiana catalyzed the transfer of xylose from UDP-xylose onto oligogalacturonides and endogenous acceptors. The products formed could be hydrolyzed with an XGA-specific hydrolase. These results confirm that the XGD1 protein is a XGA xylosyltransferase. The protein was shown by expression of a fluorescent fusion protein in N. benthamiana to be localized in the Golgi vesicles as expected for a glycosyltransferase involved in pectin biosynthesis.

  12. Spred2 is involved in imatinib-induced cytotoxicity in chronic myeloid leukemia cells

    SciTech Connect (OSTI)

    Liu, Xiao-Yun; Yang, Yue-Feng; Wu, Chu-Tse; Xiao, Feng-Jun; Zhang, Qun-Wei [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China)] [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China); Ma, Xiao-Ni [Lanzhou University of Technology, Lanzhou 730050 (China)] [Lanzhou University of Technology, Lanzhou 730050 (China); Li, Qing-Fang; Yan, Jun [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China)] [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China); Wang, Hua, E-mail: wanghualjh@gmail.com [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China)] [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China); Wang, Li-Sheng, E-mail: wangls@nic.bmi.ac.cn [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China)] [Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing 100850 (China)

    2010-03-19

    Spreds, a recently established class of negative regulators of the Ras-ERK (extracellular signal-regulated kinase) pathway, are involved in hematogenesises, allergic disorders and tumourigenesis. However, their role in hematologic neoplasms is largely unknown. Possible effects of Spreds on other signal pathways closely related to Ras-ERK have been poorly investigated. In this study, we investigated the in vitro effects of Spred2 on chronic myeloid leukemia (CML) cells. In addition to inhibiting the well-established Ras-ERK cascade, adenovirus-mediated Spred2 over-expression inhibits constitutive and stem cell factor (SCF)-stimulated sphingosine kinase-1 (SPHK1) and Mcl-1 expression, as well as inhibiting proliferation and inducing apoptosis in CML cells. In K562 cells and primary CML cells, imatinib induces endogenous Spred2 expression. Spred2 silencing by stable RNA interference partly protects K562 cells against imatinib-induced apoptosis. Together, these data implicate Spred2 in imatinib-induced cytotoxicity in CML cells, possibly by inhibiting the Ras-ERK cascade and the pro-survival signaling molecules SPHK1 and Mcl-1. These findings reveal potential targets for selective therapy of CML.

  13. Fracture Mechanics implications for apparent static friction coefficient in contact problems involving slip-weakening laws

    E-Print Network [OSTI]

    A. Papangelo; M. Ciavarella; J. R. Barber

    2015-06-19

    We consider the effect of differing coefficients of static and dynamic friction coefficients on the behaviour of contacts involving microslip. The classic solutions of Cattaneo and Mindlin are unchanged if the transition in coefficients is abrupt, but if it occurs over some small slip distance, the solution has some mathematical similarities with those governing the normal tractions in adhesive contact problems. In particular, if the transition to dynamic slip occurs over a sufficiently small area, we can identify a `JKR' approximation, where the transition region is condensed to a line. A local singularity in shear traction is then predicted, with a stress-intensity factor that is proportional to the the square root of the local contact pressure and to a certain integral of the friction coefficient-slip distance relation. We can also define an equivalent of the `small-scale yielding' criterion, which enables us to assess when the singular solution provides a good approximation. One consequence of the results is that the static coefficient of friction determined from force measurements in experiments is significantly smaller than the value that holds at the microscale.

  14. Involvement of growth factors and their receptors in radon-induced rat lung tumors

    SciTech Connect (OSTI)

    Leung, F.C.; Dagle, G.E.; Cross, F.T. [Pacific Northwest Lab., Richland, WA (United States)

    1992-12-31

    In this paper we examine the role of growth factors (GF) and their receptors (GFR) in radon-induced rat lung tumors. Inhalation exposure of radon and its daughters induced lung tumors in rats, but the molecule/cellular mechanisms are not known. Recent evidence suggests that GF/GFR play a critical role in the growth and development of lung cancer in humans and animals. We have developed immunocytochemical methods for identifying sites of production and action of GF/GFR at the cellular level; for example, the avidin-biotin horseradish peroxidase technique. In radon-induced rat epidermoid carcinomas, epidermal growth factor (EGF), EGF-receptors (EGF-R), transforming growth factor alpha (TGF-{alpha}), and bombesin were found to be abnormally expressed. These abnormal expressions, mainly associated with epidermoid carcinomas of the lung, were not found in any other lung tumor types. Our data suggest that EGF, EGF-R, TGF-{alpha}, and bombesin are involved in radon oncogenesis in rat lungs, especially in epidermoid carcinomas, possibly through the autocrine/paracrine pathway.

  15. Chemical kinetics and combustion modeling

    SciTech Connect (OSTI)

    Miller, J.A. [Sandia National Laboratories, Livermore, CA (United States)

    1993-12-01

    The goal of this program is to gain qualitative insight into how pollutants are formed in combustion systems and to develop quantitative mathematical models to predict their formation rates. The approach is an integrated one, combining low-pressure flame experiments, chemical kinetics modeling, theory, and kinetics experiments to gain as clear a picture as possible of the process in question. These efforts are focused on problems involved with the nitrogen chemistry of combustion systems and on the formation of soot and PAH in flames.

  16. Fermionic Models with Superconducting Circuits

    E-Print Network [OSTI]

    U. Las Heras; L. García-Álvarez; A. Mezzacapo; E. Solano; L. Lamata

    2015-03-31

    We propose a method for the efficient quantum simulation of fermionic systems with superconducting circuits. It consists in the suitable use of Jordan-Wigner mapping, Trotter decomposition, and multiqubit gates, be with the use of a quantum bus or direct capacitive couplings. We apply our method to the paradigmatic cases of 1D and 2D Fermi-Hubbard models, involving couplings with nearest and next-nearest neighbours. Furthermore, we propose an optimal architecture for this model and discuss the benchmarking of the simulations in realistic circuit quantum electrodynamics setups.

  17. Modelling Time

    E-Print Network [OSTI]

    Burra G. Sidharth

    2008-09-03

    We briefly review two concepts of time - the usual time associated with "being" and more recent ideas, answering to the description of "becoming". The approximation involved in the former is examined. Finally we argue that it is (unpredictable) fluctuations that underlie time.

  18. Methodology for the Assessment of the Macroeconomic Impacts of Stricter CAFE Standards - Addendum

    Reports and Publications (EIA)

    2002-01-01

    This assessment of the economic impacts of Corporate Average Fuel Economy (CAFÉ) standards marks the first time the Energy Information Administration has used the new direct linkage of the DRI-WEFA Macroeconomic Model to the National Energy Modeling System (NEMS) in a policy setting. This methodology assures an internally consistent solution between the energy market concepts forecast by NEMS and the aggregate economy as forecast by the DRI-WEFA Macroeconomic Model of the U.S. Economy.

  19. Investigations of the Fundamental Surface Reactions Involved in the Sorption and Desorption of Radionuclides

    SciTech Connect (OSTI)

    Czerwinski, Ken; Heske, Clemens; Moser, Duane; Misra, Mnoranjan; McMillion, Glen

    2011-04-20

    Models for describing solution- and surface-phase reactions have been used for 30 years, but only recently applicable to complex surfaces. Duff et al., using micro-XANES, found that Pu was concentrated on Mn-oxide and smectite phases of zeolitic tuff, providing an evaluation of contaminant speciation on surfaces for modeling. Experiments at Los Alamos demonstrated that actinides display varying surface residence time distributions, probably reflective of mineral surface heterogeneity. We propose to investigate the sorption/desorption behavior of radionuclides from mineral surfaces, as effected by microorganisms, employing isolates from Nevada Test Site deep alluvium as a model system. Characterizations will include surface area, particle size distribution, x-ray diffraction (XRD), microprobe analysis, extractions, and microbiology. Surface interactions will be assessed by electron spectroscopy (XPS), x-ray absorption fine structure spectroscopy (XAFS), X-ray emission spectroscopy, transmission electron microscopy (TEM) and Scanning electron microscopy (SEM). Desert Research Institute (DRI), University of Nevada, Reno (UNR), and University of Nevada, Las Vegas (UNLV) researchers will collaborate to enhance scientific infrastructure and the understanding of contaminant behavior on surfaces, with broader implications for the management of DOE sites.

  20. A supersymmetric model for graphene

    E-Print Network [OSTI]

    Everton M. C. Abreu; Marco A. De Andrade; Leonardo P. G. de Assis; Jose A. Helayel-Neto; A. L. M. A. Nogueira; Ricardo C. Paschoal

    2014-07-21

    In this work, we focus on the fermionic structure of the low-energy excitations of graphene (a monolayer of carbon atoms) to propose a new supersymmetric field-theoretic model for this physical system. In the current literature, other proposals for describing graphene physics have been contemplated at the level of supersymmetric quantum mechanics. Also, by observing the inhomogeneities between neighbor carbon atoms, Jackiw {\\it et al.} have set up an interesting chiral Abelian gauge theory. We show in this paper that our formulation encompasses models discussed previously as sectors of an actually richer (supersymmetric) planar gauge model. Possible interpretations for the fields involved in the present graphene model are proposed and the question of supersymmetry breaking is discussed.

  1. Involvement of Arabidopsis RACK1 in Protein Translation and Its Regulation by Abscisic Acid

    SciTech Connect (OSTI)

    Guo, Jianjun [University of British Columbia, Vancouver; Wang, Shucai [University of British Columbia, Vancouver; Valerius, Oliver [Universitaet Goettingen, Goettingen, Germany; Hall, Hardy [University of British Columbia, Vancouver; Zeng, Qingning [University of British Columbia, Vancouver; Li, Jian-Feng [Harvard University; Weston, David [ORNL; Ellis, Brian [University of British Columbia, Vancouver; Chen, Jay [ORNL

    2011-01-01

    Earlier studies have shown that RACK1 functions as a negative regulator of ABA responses in Arabidopsis, but the molecular mechanism of the action of RACK1 in these processes remains elusive. Global gene expression profiling revealed that approximately 40% of the genes affected by ABA treatment were affected in a similar manner by the rack1 mutation, supporting the view that RACK1 is an important regulator of ABA responses. On the other hand, co-expression analysis revealed that >80% of the genes co-expressed with RACK1 encode ribosome proteins, implying a close relationship between RACK1 s function and the ribosome complex. These results implied that the regulatory role for RACK1 in ABA responses may be partially due to its putative function in protein translation, which is one of the major cellular processes that mammalian and yeast RACK1 is involved in. Consistently, all three Arabidopsis RACK1 homologous genes, namely RACK1A, RACK1B and RACK1C, complemented the growth defects of the S. cerevisiae cpc2/rack1 mutant. In addition, RACK1 physically interacts with Arabidopsis Eukaryotic Initiation Factor 6 (eIF6), whose mammalian homologue is a key regulator of 80S ribosome assembly. Moreover, rack1 mutants displayed hypersensitivity to anisomycin, an inhibitor of protein translation, and displayed characteristics of impaired 80S functional ribosome assembly and 60S ribosomal subunit biogenesis in a ribosome profiling assay. Gene expression analysis revealed that ABA inhibits the expression of both RACK1 and eIF6. Taken together, these results suggest that RACK1 may be required for normal production of 60S and 80S ribosomes and that its action in these processes may be regulated by ABA.

  2. Consent Versus Consensus - Stakehold Involvement in the Identification of Necessary and Sufficient Transportation

    SciTech Connect (OSTI)

    Fawcett, Ricky Lee; Kramer, George Leroy Jr.

    2003-03-01

    Transportation (DOT) and the Nuclear Regulatory Commission (NRC) to provide for the protection of the public and the environment; historically these regulations have proven quite sufficient. Even so, when the Department of Energy (DOE) makes radioactive materials shipments, that are deemed to be a major federal activity, regulations under the National Environmental Policy Act require that public input on safety issues be sought. This requirement leads to interactions with State, Tribal and local stakeholders that often result in the imposition of extra-regulatory requirements – requirements beyond those prescribed by DOT and NRC regulations. Unfortunately, these additional requirements virtually always increase costs and delay schedules, and usually do so without significantly increasing, and possibly even decreasing overall transportation safety. We believe that this problem arises because of efforts to achieve stakeholder consensus rather than stakeholder consent, where “consensus” connotes universal agreement with all aspects of the program, while “consent”, as used here, is simple agreement with the overall course of action. Gaining consensus entails extensive negotiations because all aspects and requirements of the project must be agreed to by each stakeholder. Gaining consent, on the other hand, requires only that stakeholders be satisfied that the project, as planned, provides adequately for their safety needs. This article addresses the issue of consent versus consensus and proposes a systematic, decision science process for reaching consent. Key steps in this proposed process are early identification and involvement of stakeholders, compilation of their concerns, perceptions, needs, causes, and translation of that information into an appropriate set of “derived requirements.” These derived requirements, along with already-established DOT and NRC regulatory requirements, form the necessary and sufficient conditions for safe transportation and for obtaining stakeholder consent.

  3. Substrate binding by a bacterial ABC transporter involved in polysaccharide export

    SciTech Connect (OSTI)

    Cuthbertson, Leslie; Kimber, Matthew S.; Whitfield, Chris (Guelph)

    2008-04-02

    ATP-binding-cassette (ABC) transporters are responsible for the export of a wide variety of cell-surface glycoconjugates in both Gram-positive and Gram-negative bacteria. These include the O-antigenic polysaccharide (O-PS) portion of lipopolysaccharide, a crucial virulence determinant in Gram-negative pathogens. O-PSs are synthesized by one of two fundamentally different pathways. Escherichia coli O serotypes O8 and O9a provide the prototype systems for studying O-PS export via ABC transporters. The transporter is composed of the transmembrane component Wzm and the nucleotide-binding component Wzt. Although the N-terminal domain of Wzt is a conventional ABC protein, the C-terminal domain of Wzt (C-Wzt) is a unique structural element that determines the specificity of the transporter for either the O8 or O9a O-PS. We show here that the two domains of Wzt can function when expressed as separate polypeptides; both are essential for export. In vitro, C-Wzt binds its cognate O-PS by recognizing a residue located at the nonreducing end of the polymer. The crystal structure of C-WztO9a is reported here and reveals a {beta} sandwich with an immunoglobulin-like topology that contains the O-PS-binding pocket. Substrate interactions with nucleotide-binding domains have been demonstrated in an ABC exporter previously. However, to our knowledge substrate binding by a discrete, cytoplasmic accessory domain in an extended nucleotide-binding domain polypeptide has not previously been demonstrated. Elucidation of the substrate-recognition system involved in O-PS export provides insight into the mechanism that coordinates polymer biosynthesis, termination, and export.

  4. Hot Water Distribution System Model Enhancements

    SciTech Connect (OSTI)

    Hoeschele, M.; Weitzel, E.

    2012-11-01

    This project involves enhancement of the HWSIM distribution system model to more accurately model pipe heat transfer. Recent laboratory testing efforts have indicated that the modeling of radiant heat transfer effects is needed to accurately characterize piping heat loss. An analytical methodology for integrating radiant heat transfer was implemented with HWSIM. Laboratory test data collected in another project was then used to validate the model for a variety of uninsulated and insulated pipe cases (copper, PEX, and CPVC). Results appear favorable, with typical deviations from lab results less than 8%.

  5. Modeling Control Mechanisms with Normative Multiagent Systems

    E-Print Network [OSTI]

    van der Torre, Leon

    of renewable energy. We apply a conceptual model based on normative multiagent systems (NMAS). We propose to stimulate the production of #12;energy from renewable sources [20]. The ruling involves an obligation for energy sup- pliers to produce evidence of having distributed a certain minimal amount of renewable energy

  6. A Dark Energy Model in Lyra Manifold

    E-Print Network [OSTI]

    Hoavo Hova

    2012-04-11

    We consider, in normal-gauge Lyra's geometry, evolution of a homogeneous isotropic universe in a gravitational model involving only the standard matter in interaction with a displacement vector field $\\phi_{\\mu}$. Considering both constant and time-dependent displacement vector field we show that the observed cosmic acceleration could be explained without considering an alien energy component with a negative pressure.

  7. A Dark Energy Model in Lyra Manifold

    E-Print Network [OSTI]

    Hova, Hoavo

    2012-01-01

    We consider, in normal-gauge Lyra's geometry, evolution of a homogeneous isotropic universe in a gravitational model involving only the standard matter in interaction with a displacement vector field $\\phi_{\\mu}$. Considering both constant and time-dependent displacement vector field we show that the observed cosmic acceleration could be explained without considering an alien energy component with a negative pressure.

  8. Predicting species invasions using ecological niche modeling

    E-Print Network [OSTI]

    Peterson, A. Townsend; Vieglais, David A.

    2001-05-01

    ) and commission (including niche space not ,lctually occupied by the 'pecies). Each algorithm for modeling specIes' ecological niches involves a specific com binatiol1 of errors of omission ,md commission. A rel.ltively new approach, called the (;enetic...

  9. Water Budget Analysis and Groundwater Inverse Modeling 

    E-Print Network [OSTI]

    Farid Marandi, Sayena

    2012-07-16

    and seasonality of local/regional hydrological processes. The model involved a transient two- dimensional hydrogeological simulation of the multi-layered aquifer. In the second part of the thesis, a Markov Chain Monte Carlo (MCMC) method were developed to estimate...

  10. EPSRC CASE Studentship Statistical Modelling of Fingerprints

    E-Print Network [OSTI]

    Oakley, Jeremy

    and mathematics together with experience or strong interest in statistical computing (including programming in R1 EPSRC CASE Studentship Statistical Modelling of Fingerprints SUMMARY This CASE studentship involves working with researchers in the Statistics & Interpretation Group of the Forensic Science Service

  11. Impacts of Unconventional Gas Technology in the Annual Energy Outlook 2000

    Reports and Publications (EIA)

    2000-01-01

    This paper describes the methodology used in the National Energy Modeling System (NEMS) to represent unconventional gas technologies and their impacts on projections in the Annual Energy Outlook 2000 (AEO2000).

  12. Computational Nanotechnology: From Clusters to Devices David Tomnek

    E-Print Network [OSTI]

    Tománek, David

    Computational Nanotechnology: From Clusters to Devices David Tománek Physics and Astronomy contraction, and even nanoscale bonding systems for NEMS devices. Keywords: Nanotechnology, Supercomputing to design and test future building blocks of Nanotechnology. Computer modeling is an indispensable tool

  13. A look at the ocean in the EC-Earth climate model Andreas Sterl Richard Bintanja Laurent Brodeau Emily Gleeson

    E-Print Network [OSTI]

    Haak, Hein

    to the special issue on EC-Earth, a global climate and earth system model based on the seasonal forecast system-011-1239-2 #12;phytoplankton) processes are involved. To study such complex interactions, Earth System Models

  14. Public Involvement Plan Public Involvement Plan

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page on Delicious RankADVANCED MANUFACTURINGEnergy BillsNo. 195 - Oct. 7, 2011 | DepartmentFunds for2002 | DepartmentPublic

  15. Application of the SCALE TSUNAMI Tools for the Validation of Criticality Safety Calculations Involving 233U

    SciTech Connect (OSTI)

    Mueller, Don [ORNL; Rearden, Bradley T [ORNL; Hollenbach, Daniel F [ORNL

    2009-02-01

    The Radiochemical Development Facility at Oak Ridge National Laboratory has been storing solid materials containing 233U for decades. Preparations are under way to process these materials into a form that is inherently safe from a nuclear criticality safety perspective. This will be accomplished by down-blending the {sup 233}U materials with depleted or natural uranium. At the request of the U.S. Department of Energy, a study has been performed using the SCALE sensitivity and uncertainty analysis tools to demonstrate how these tools could be used to validate nuclear criticality safety calculations of selected process and storage configurations. ISOTEK nuclear criticality safety staff provided four models that are representative of the criticality safety calculations for which validation will be needed. The SCALE TSUNAMI-1D and TSUNAMI-3D sequences were used to generate energy-dependent k{sub eff} sensitivity profiles for each nuclide and reaction present in the four safety analysis models, also referred to as the applications, and in a large set of critical experiments. The SCALE TSUNAMI-IP module was used together with the sensitivity profiles and the cross-section uncertainty data contained in the SCALE covariance data files to propagate the cross-section uncertainties ({Delta}{sigma}/{sigma}) to k{sub eff} uncertainties ({Delta}k/k) for each application model. The SCALE TSUNAMI-IP module was also used to evaluate the similarity of each of the 672 critical experiments with each application. Results of the uncertainty analysis and similarity assessment are presented in this report. A total of 142 experiments were judged to be similar to application 1, and 68 experiments were judged to be similar to application 2. None of the 672 experiments were judged to be adequately similar to applications 3 and 4. Discussion of the uncertainty analysis and similarity assessment is provided for each of the four applications. Example upper subcritical limits (USLs) were generated for application 1 based on trending of the energy of average lethargy of neutrons causing fission, trending of the TSUNAMI similarity parameters, and use of data adjustment techniques.

  16. Systematic identification of genes and transduction pathways involved in radio-adaptive response

    SciTech Connect (OSTI)

    Wu, Honglu

    2015-05-22

    Low doses of radiation have been shown to protect against the biological effects of later exposure to toxic levels of radiation. In this study, we propose to identify the molecular mechanisms of this adaptive response by systematically identifying the genes that play a role in radio-protection. In the original proposal, a human cell line that is well-documented to exhibit the radio-adaptive effect was to be used. In this revised study plan, we will use a mouse model, C57BL/6, which has also been well investigated for radio-adaptation. The goal of the proposed study is to enhance our understanding of cellular responses to low doses of radiation exposure at the molecular level.

  17. A new development in microcomputer software for mine ventilation planning involving the installation of fans

    SciTech Connect (OSTI)

    O'Leary, M.S.J.; McPherson, M.J.

    1989-01-01

    This paper introduces a computer simulation that extends the use of microcomputer systems for mine ventilation planning. The program was developed as part of an ongoing study to produce a simulation model that would determine the optimum duties of a main fan and a booster fan without requiring the trial-and-error runs that are necessary with currently available programs. To use the new program, the user specifies the location of one main fan and one booster fan, and the minimum required airflows in any number of working places. The computer determines the fan duties that maintains the required airflows at the lowest operating costs without causing undesired recirculation. The methodology of the program and an example showing how it can be applied are presented.

  18. Early Brain Response to Low-Dose Radiation Exposure Involves Molecular Networks and Pathways Associated with Cognitive Functions, Advanced Aging and Alzheimer's Disease

    E-Print Network [OSTI]

    Lowe, Xiu R

    2009-01-01

    Early brain response to low-dose radiation exposure involvesRunning Title: Low dose radiation affects cognitive functionEarly brain response to low-dose radiation exposure involves

  19. Particle-Hole Optical Model: Fantasy or Reality?

    E-Print Network [OSTI]

    M. H. Urin

    2010-05-13

    An attempt to formulate the optical model of particle-hole-type excitations (including giant resonances) is undertaken. The model is based on the Bethe--Goldstone equation for the particle-hole Green function. This equation involves a specific energy-dependent particle-hole interaction that is due to virtual excitation of many-quasiparticle configurations and responsible for the spreading effect. After energy averaging, this interaction involves an imaginary part. The analogy between the single-quasiparticle and particle-hole optical models is outlined.

  20. Enhancing Financial Decision-Making Using Social Behavior Modeling

    E-Print Network [OSTI]

    movements. This pro- cess can be modeled by connecting online social behavior and future trading behaviorEnhancing Financial Decision-Making Using Social Behavior Modeling Ruoqian Liu, Ankit Agrawal, Wei is a social activity that involves every par- ticipant's decision making. Meanwhile, people's online be

  1. A Deep Hybrid Model for Weather Forecasting Aditya Grover

    E-Print Network [OSTI]

    Horvitz, Eric

    @microsoft.com ABSTRACT Weather forecasting is a canonical predictive challenge that has depended primarily on model-based methods. We ex- plore new directions with forecasting weather as a data- intensive challenge that involves the joint statistics of a set of weather-related vari- ables. We show how the base model can be enhanced

  2. Modeling civil violence: An agent-based computational approach

    E-Print Network [OSTI]

    Tesfatsion, Leigh

    ," I do so advisedly, recognizing that no political or social order is represented in the model of revolutions properly speaking. The dynamics of decentralized upheaval, rather than its political substance Against Central Authority This model involves two categories of actors. ``Agents'' are members

  3. BIOMECHANICAL MODELING AND SIMULATION WITHIN A MEDICAL SIMULATOR FRAMEWORK

    E-Print Network [OSTI]

    Wolf, Christian

    BIOMECHANICAL MODELING AND SIMULATION WITHIN A MEDICAL SIMULATOR FRAMEWORK -- 18 months post the LIRIS Lab. (http://liris.cnrs.fr/~saara) is involved in the elaboration of an optimal biomechanical in the development of modules for bio-mechanical modeling and simulation, and their integrated within a framework (i

  4. Autism: Reduced Connectivity between Cortical Areas Involved in Face Expression, Theory of Mind, and the Sense of Self

    E-Print Network [OSTI]

    Feng, Jianfeng

    1 Autism: Reduced Connectivity between Cortical Areas Involved in Face Expression, Theory of Mind head: Functional connectivity in autism # These authors contributed equally to this work resting-state functional connectivity was analyzed in 523 people with autism and 452 typically developing

  5. Robotics Minor Robotics is a truly interdisciplinary minor, involving expertise in the fields of computer science, electrical

    E-Print Network [OSTI]

    Massachusetts at Lowell, University of

    Robotics Minor Robotics is a truly interdisciplinary minor, involving expertise in the fields-requisites to the minor courses: Calculus I, Calculus II, Physics I, and Physics II or electricity. Robotics Minor.265 Logic Design 16.317 Microprocessors Systems Design I 22.211 Statics 22.213 Dynamics 22.579 Robotics

  6. Holistic Therapy Holistic Massage: This hour long session involves a complete relaxation of the body while easing

    E-Print Network [OSTI]

    O'Mahony, Donal E.

    Elements Holistic Therapy Clinic Holistic Massage: This hour long session involves a complete. Leaving you re-vitalised, supple and ready for life. 1 ½ hours available. Back, Neck and Shoulders boost Massage: This half an hour session relieves the back of stress knots and stiffness built up within

  7. CER4 Encodes an Alcohol-Forming Fatty Acyl-Coenzyme A Reductase Involved in Cuticular Wax Production

    E-Print Network [OSTI]

    Kunst, Ljerka

    CER4 Encodes an Alcohol-Forming Fatty Acyl-Coenzyme A Reductase Involved in Cuticular Wax surfaces of land plants. It is composed of a cutin polymer matrix and waxes. Cuticular waxes are complex and characterization of CER4, a wax bio- synthetic gene from Arabidopsis (Arabidopsis thaliana). Arabidopsis cer4

  8. What is Your Environmental Wellness? The environmental dimension involves accepting the impact we have on our world and doing something

    E-Print Network [OSTI]

    What is Your Environmental Wellness? The environmental dimension involves accepting the impact we sprays. _____ 7. I do not litter. _____ 8. I volunteer my time for environmental conservation projects about doing my part to preserve the environment. _____ Total for Environmental Wellness SCORE MEANING 15

  9. Bottomonium spectroscopy and radiative transitions involving the ?[subscript bJ](1P,2P) states at BaBar

    E-Print Network [OSTI]

    Lees, J.?P.

    We use (121 ± 1) million ?(3S) and (98 ± 1) million ?(2S) mesons recorded by the BABAR detector at the PEP-II e[superscript +]e[superscript -] collider at SLAC to perform a study of radiative transitions involving the ...

  10. Identification and characterization of a pyridoxal reductase involved in the vitamin B6 salvage pathway in Arabidopsis

    E-Print Network [OSTI]

    Daub, Margaret

    Identification and characterization of a pyridoxal reductase involved in the vitamin B6 salvage Springer Science+Business Media B.V. 2011 Abstract Vitamin B6 (pyridoxal phosphate) is an essen- tial between the six vitamin B6 vitamers. A putative pyridoxal reductase (PLR1) was identified in Arabidopsis

  11. 162 Electrical and Computer Engineering 163 Courses and projects that actively involve them in their own education and

    E-Print Network [OSTI]

    Richards-Kortum, Rebecca

    · A broad education outside of engineering and science that emphasizes the role of electrical and computer162 Electrical and Computer Engineering 163 · Courses and projects that actively involve them in their own education and enhance their ability to formulate and solve real-world design and research problems

  12. Supply chain management (SCM) involves the management of materials and information across the entire supply chain. This includes raw material

    E-Print Network [OSTI]

    Calgary, University of

    the entire supply chain. This includes raw material suppliers, component producers, final assemblySupply chain management (SCM) involves the management of materials and information across this concentration will be required to take three core courses: Materials and Supply Chain Management, Transportation

  13. Benzodiazepine Withdrawal-Induced Glutamatergic Plasticity Involves Up-Regulation of GluR1-Containing -Amino-3-

    E-Print Network [OSTI]

    Abraham, Nader G.

    Benzodiazepine Withdrawal-Induced Glutamatergic Plasticity Involves Up-Regulation of GluR1 and addiction. Benzodiazepine withdrawal results in increased glutamatergic strength, but whether -amino-3 remodeled during benzodiazepine withdrawal is uncertain. Whole-cell recordings of rat hippocampal CA1

  14. In this effort, we describe a face database obtained by using an involved acquisition system for the collection of

    E-Print Network [OSTI]

    Abidi, Mongi A.

    relies heavily on illumination. Thermal IR imagery, being a representation of the radiated thermal energy when involving multi-band visible and thermal information. The database has applications/monochromatic image, one thermal image and the spectral distribution of the illumination of the scene. The complete

  15. Distinct osmo-sensing protein kinase pathways are involved in signalling moderate and severe hyper-osmotic

    E-Print Network [OSTI]

    Hirt, Heribert

    Distinct osmo-sensing protein kinase pathways are involved in signalling moderate and severe hyper-osmotic is severely affected by hyper-osmotic salt conditions. Although a number of salt-induced genes have been and extreme hyper-osmotic conditions. A 46 kDa protein kinase was found to be activated by elevated salt

  16. Transportation of Dangerous Goods Anyone involved with the Transportation of Dangerous Goods must be trained. This includes shipping

    E-Print Network [OSTI]

    TDG Transportation of Dangerous Goods Anyone involved with the Transportation of Dangerous Goods must be trained. This includes shipping and receiving. All receiving of Dangerous Goods for the Science in Departmental Offices or labs. How do you know if the package is a dangerous goods shipment? Parcels containing

  17. Whether it's designing rehabilitation strategies involving electricity to `retrain' damaged nerves, developing optical imaging systems to build

    E-Print Network [OSTI]

    Whether it's designing rehabilitation strategies involving electricity to `retrain' damaged nerves-ready rehabilitation products is only part of the equation. As part of her CARE (CREATE Academic Rehabilitation in the commercialization of two important rehabilitation products for the Staxi Corporation.Working out of the iDAPT `Home

  18. The Effects of an Intervention to Foster a Caring and Task-Involving Climate at a University Recreation Center

    E-Print Network [OSTI]

    Brown, Theresa Clare

    2011-04-21

    of the following: a) climate (e.g. perceptions of the caring, task-, and ego-involving climates), b) psychological needs (e.g. autonomy, competence, and relatedness), c) motivational responses (e.g. extrinsic and intrinsic motivation), d) commitment to exercise...

  19. Involvement of Extracellular Signal-Regulated Kinase (ERK) in Pardaxin-Induced Dopamine Release from PC12 Cells

    E-Print Network [OSTI]

    Linial, Michal

    Involvement of Extracellular Signal-Regulated Kinase (ERK) in Pardaxin-Induced Dopamine Release kinase (ERK)/mitogen-activated protein kinase (MAPK) in pardaxin-induced dopamine (DA) release DA release. Time course exper- iments indicated that PX, at nontoxic concentrations, stimu- lated ERK

  20. Planning for multiple mobile robots in dynamic environ-ments involves determining the optimal path each robot

    E-Print Network [OSTI]

    Stentz, Tony

    Abstract Planning for multiple mobile robots in dynamic environ- ments involves determining the optimal path each robot should follow to accomplish the goals of the mission, given the current knowledge reassign robots to goals in order to continually minimize the time to complete the mission. In this paper

  1. A Lipid-modified Phosphoinositide-specific Phospholipase C (TcPI-PLC) Is Involved in Differentiation of Trypomastigotes to

    E-Print Network [OSTI]

    Singer, Randall

    A Lipid-modified Phosphoinositide-specific Phospholipase C (TcPI-PLC) Is Involved C (PI- PLC) is an important component of the inositol phos- phate/diacylglycerol signaling pathway. A newly discov- ered Trypanosoma cruzi PI-PLC (TcPI-PLC) is lipid modified in its N terminus, targeted

  2. Human Fertilisation and Embryology Bill A briefing for MPs on the need for research involving human and human admixed embryos.

    E-Print Network [OSTI]

    Rambaut, Andrew

    cells for research. The Bill allows research, under license, on four types of HAEs, which contain bothHuman Fertilisation and Embryology Bill A briefing for MPs on the need for research involving human and human admixed embryos. Prepared by the Academy of Medical Sciences, the Medical Research Council

  3. Mass Spectroscopy of Chemical Reaction of 3d Metal Clusters Involved in Chemical Vapor Deposition Synthesis of Carbon Nanotubes

    E-Print Network [OSTI]

    Maruyama, Shigeo

    -labeled experiments. KEYWORDS: cluster, iron, cobalt, nickel, FT-ICR, single-walled carbon nanotubes *Present address Synthesis of Carbon Nanotubes Shuhei Inoue* and Shigeo Maruyama Department of Mechanical Engineering importance. For example, these reactions are involved in the synthesis of single-walled carbon nanotubes

  4. NPS Institutional Review Board (IRB) Interim Guidance on Human Subjects Research Involving Surveys, Questionnaires, Interviews, and Focus Groups

    E-Print Network [OSTI]

    NPS Institutional Review Board (IRB) Interim Guidance on Human Subjects Research Involving Surveys only those data collection activities related to human subjects research. To ensure NPS by the IRB must balance the needs, responsibilities, and risks related to the research subjects, the student

  5. Honours Programmes involving Physics and Astronomy, March 2015 Page 1 Entering SH within Physics and Astronomy and Joint Degrees -2015

    E-Print Network [OSTI]

    Greenaway, Alan

    Honours Programmes involving Physics and Astronomy, March 2015 Page 1 Entering SH within Physics subject to University approvals, we plan to offer BSc Mathematics and Physics students a choice of Maths or Physics project. Some details of the modules open to you are in the University's Course Catalogue

  6. Resource allocatiion: sequential data collection for reliability analysis involving systems and component level data

    SciTech Connect (OSTI)

    Anderson-cooke, Christine M [Los Alamos National Laboratory

    2010-01-01

    In analyzing the reliability of complex systems, several types of data from full-system tests to component level tests are commonly available and are used. After a preliminary analysis, additional resources may be available to collect new data. The goal of resource allocation is to identify the best new data to collect to maximally improve the prediction of system reliability. While several possible definitions of 'maximally improve' are possible, we focus on reducing the uncertainty or the width of the uncertainty interval for the prediction of system reliability at a user-specified age(s). In this paper, we present an algorithm that allows us to estimate the anticipated improvement to the analysis with the addition of new data, based on current understanding of all of the statistical model parameters. This quantitative assessment of the anticipated improvement can be helpful to justify the benefits of collecting new data. Additionally by comparing different potential allocations, it is possible to determine what new data should be collected to improve our understanding of the response. This optimization takes into account the relative cost of different data types and can be based on flexible allocation options, or subject to logistical constraints.

  7. Climate Change Scenario Planning in Alaska's National Parks: Stakeholder Involvement in the Decision-Making Process

    SciTech Connect (OSTI)

    Ernst, Kathleen M; Van Riemsdijk, Dr. Micheline

    2013-01-01

    This article studies the participation of stakeholders in climate change decision-making in Alaska s National Parks. We place stakeholder participation within literatures on environmental and climate change decision-making. We conducted participant observation and interviews in two planning workshops to investigate the decision-making process, and our findings are three-fold. First, the inclusion of diverse stakeholders expanded climate change decision-making beyond National Park Service (NPS) institutional constraints. Second, workshops of the Climate Change Scenario Planning Project (CCSPP) enhanced institutional understandings of participants attitudes towards climate change and climate change decision-making. Third, the geographical context of climate change influences the decision-making process. As the first regional approach to climate change decision-making within the NPS, the CCSPP serves as a model for future climate change planning in public land agencies. This study shows how the participation of stakeholders can contribute to robust decisions, may move climate change decision-making beyond institutional barriers, and can provide information about attitudes towards climate change decision-making.

  8. Climate change scenario planning in Alaska's National Parks: Stakeholder involvement in the decision-making process

    SciTech Connect (OSTI)

    Ernst, Kathleen M; Van Riemsdijk, Dr. Micheline

    2013-01-01

    This article studies the participation of stakeholders in climate change decision-making in Alaska s National Parks. We place stakeholder participation within literatures on environmental and climate change decision-making. We conducted participant observation and interviews in two planning workshops to investigate the decision-making process, and our findings are three-fold. First, the inclusion of diverse stakeholders expanded climate change decision-making beyond National Park Service (NPS) institutional constraints. Second, workshops of the Climate Change Scenario Planning Project (CCSPP) enhanced institutional understandings of participants attitudes towards climate change and climate change decision-making. Third, the geographical context of climate change influences the decisionmaking process. As the first regional approach to climate change decision-making within the NPS, the CCSPP serves as a model for future climate change planning in public land agencies. This study shows how the participation of stakeholders can contribute to robust decisions, may move climate change decision-making beyond institutional barriers, and can provide information about attitudes towards climate change decision-making.

  9. Maturity Model for Advancing Smart Grid Interoperability

    SciTech Connect (OSTI)

    Knight, Mark; Widergren, Steven E.; Mater, J.; Montgomery, Austin

    2013-10-28

    Abstract—Interoperability is about the properties of devices and systems to connect and work properly. Advancing interoperability eases integration and maintenance of the resulting interconnection. This leads to faster integration, lower labor and component costs, predictability of projects and the resulting performance, and evolutionary paths for upgrade. When specifications are shared and standardized, competition and novel solutions can bring new value streams to the community of stakeholders involved. Advancing interoperability involves reaching agreement for how things join at their interfaces. The quality of the agreements and the alignment of parties involved in the agreement present challenges that are best met with process improvement techniques. The GridWise® Architecture Council (GWAC) sponsored by the United States Department of Energy is supporting an effort to use concepts from capability maturity models used in the software industry to advance interoperability of smart grid technology. An interoperability maturity model has been drafted and experience is being gained through trials on various types of projects and community efforts. This paper describes the value and objectives of maturity models, the nature of the interoperability maturity model and how it compares with other maturity models, and experiences gained with its use.

  10. Model Selection for the Competing-Risks Model With and Without Masking

    E-Print Network [OSTI]

    Lee, Thomas

    Department of Statistics Colorado State University Fort Collins, CO 80523-1877 (tlee@stat.colostate.edu) The competing-risks model is useful in settings in which individuals (or units) may die (or fail) because for competing-risks data with and without masking involves the specification of cause-specific hazard rates

  11. Modeling of Laser-Induced Metal Combustion

    SciTech Connect (OSTI)

    Boley, C D; Rubenchik, A M

    2008-02-20

    Experiments involving the interaction of a high-power laser beam with metal targets demonstrate that combustion plays an important role. This process depends on reactions within an oxide layer, together with oxygenation and removal of this layer by the wind. We present an analytical model of laser-induced combustion. The model predicts the threshold for initiation of combustion, the growth of the combustion layer with time, and the threshold for self-supported combustion. Solutions are compared with detailed numerical modeling as benchmarked by laboratory experiments.

  12. Heavy Flavor Simplified Models at the LHC

    SciTech Connect (OSTI)

    Essig, Rouven; /YITP, Stony Brook /Princeton, Inst. Advanced Study /SLAC; Izaguirre, Eder; /SLAC /Stanford U., Phys. Dept.; Kaplan, Jared; Wacker, Jay G.; /SLAC

    2012-04-03

    We consider a comprehensive set of simplified models that contribute to final states with top and bottom quarks at the LHC. These simplified models are used to create minimal search strategies that ensure optimal coverage of new heavy flavor physics involving the pair production of color octets and triplets. We provide a set of benchmarks that are representative of model space, which can be used by experimentalists to perform their own optimization of search strategies. For data sets larger than 1 fb{sup -1}, same-sign dilepton and 3b search regions become very powerful. Expected sensitivities from existing and optimized searches are given.

  13. Moist multi-scale models for the hurricane embryo

    SciTech Connect (OSTI)

    Majda, Andrew J. [New York University; Xing, Yulong [ORNL; Mohammadian, Majid [University of Ottawa, Canada

    2010-01-01

    Determining the finite-amplitude preconditioned states in the hurricane embryo, which lead to tropical cyclogenesis, is a central issue in contemporary meteorology. In the embryo there is competition between different preconditioning mechanisms involving hydrodynamics and moist thermodynamics, which can lead to cyclogenesis. Here systematic asymptotic methods from applied mathematics are utilized to develop new simplified moist multi-scale models starting from the moist anelastic equations. Three interesting multi-scale models emerge in the analysis. The balanced mesoscale vortex (BMV) dynamics and the microscale balanced hot tower (BHT) dynamics involve simplified balanced equations without gravity waves for vertical vorticity amplification due to moist heat sources and incorporate nonlinear advective fluxes across scales. The BMV model is the central one for tropical cyclogenesis in the embryo. The moist mesoscale wave (MMW) dynamics involves simplified equations for mesoscale moisture fluctuations, as well as linear hydrostatic waves driven by heat sources from moisture and eddy flux divergences. A simplified cloud physics model for deep convection is introduced here and used to study moist axisymmetric plumes in the BHT model. A simple application in periodic geometry involving the effects of mesoscale vertical shear and moist microscale hot towers on vortex amplification is developed here to illustrate features of the coupled multi-scale models. These results illustrate the use of these models in isolating key mechanisms in the embryo in a simplified content.

  14. Wind Technology Modeling Within the System Advisor Model (SAM) (Poster)

    SciTech Connect (OSTI)

    Blair, N.; Dobos, A.; Ferguson, T.; Freeman, J.; Gilman, P.; Whitmore, J.

    2014-05-01

    This poster provides detail for implementation and the underlying methodology for modeling wind power generation performance in the National Renewable Energy Laboratory's (NREL's) System Advisor Model (SAM). SAM's wind power model allows users to assess projects involving one or more large or small wind turbines with any of the detailed options for residential, commercial, or utility financing. The model requires information about the wind resource, wind turbine specifications, wind farm layout (if applicable), and costs, and provides analysis to compare the absolute or relative impact of these inputs. SAM is a system performance and economic model designed to facilitate analysis and decision-making for project developers, financers, policymakers, and energy researchers. The user pairs a generation technology with a financing option (residential, commercial, or utility) to calculate the cost of energy over the multi-year project period. Specifically, SAM calculates the value of projects which buy and sell power at retail rates for residential and commercial systems, and also for larger-scale projects which operate through a power purchase agreement (PPA) with a utility. The financial model captures complex financing and rate structures, taxes, and incentives.

  15. Macro-System Model: A Federated Object Model for Cross-Cutting Analysis of Hydrogen Production, Delivery, Consumption and Associated Emissions; Preprint

    SciTech Connect (OSTI)

    Ruth, M.; Diakov, V.; Goldsby, M. E.; Sa, T. J.

    2010-12-01

    It is commonly accepted that the introduction of hydrogen as an energy carrier for light-duty vehicles involves concomitant technological development of infrastructure elements, such as production, delivery, and consumption, all associated with certain emission levels. To analyze these at a system level, the suite of corresponding models developed by the United States Department of Energy and involving several national laboratories is combined in one macro-system model (MSM). The macro-system model is being developed as a cross-cutting analysis tool that combines a set of hydrogen technology analysis models. Within the MSM, a federated simulation framework is used for consistent data transfer between the component models. The framework is built to suit cross-model as well as cross-platform data exchange and involves features of 'over-the-net' computation.

  16. Modeling water waves beyond perturbations

    E-Print Network [OSTI]

    Clamond, Didier

    2015-01-01

    In this chapter, we illustrate the advantage of variational principles for modeling water waves from an elementary practical viewpoint. The method is based on a `relaxed' variational principle, i.e., on a Lagrangian involving as many variables as possible, and imposing some suitable subordinate constraints. This approach allows the construction of approximations without necessarily relying on a small parameter. This is illustrated via simple examples, namely the Serre equations in shallow water, a generalization of the Klein-Gordon equation in deep water and how to unify these equations in arbitrary depth. The chapter ends with a discussion and caution on how this approach should be used in practice.

  17. Low-Dose Involved-Field Radiation in the Treatment of Non-Hodgkin Lymphoma: Predictors of Response and Treatment Failure

    SciTech Connect (OSTI)

    Russo, Andrea L.; Chen, Yu-Hui; Martin, Neil E.; Vinjamoori, Anant; Luthy, Sarah K.; Freedman, Arnold; Michaelson, Evan M.; Silver, Barbara; Mauch, Peter M.; Ng, Andrea K.

    2013-05-01

    Purpose: To investigate clinical and pathologic factors significant in predicting local response and time to further treatment after low-dose involved-field radiation therapy (LD-IFRT) for non-Hodgkin lymphoma (NHL). Methods and Materials: Records of NHL patients treated at a single institution between April 2004 and September 2011 were retrospectively reviewed. Low-dose involved-field radiation therapy was given as 4 Gy in 2 fractions over 2 consecutive days. Treatment response and disease control were determined by radiographic studies and/or physical examination. A generalized estimating equation model was used to assess the effect of tumor and patient characteristics on disease response. A Cox proportional hazards regression model was used to assess time to further treatment. Results: We treated a total of 187 sites in 127 patients with LD-IFRT. Histologies included 66% follicular, 9% chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma, 10% marginal zone, 6% mantle cell lymphoma (MCL), and 8% other. Median follow-up time was 23.4 months (range, 0.03-92.2 months). The complete response, partial response, and overall response rates were 57%, 25%, and 82%, respectively. A CLL histology was associated with a lower response rate (odds ratio 0.2, 95% confidence interval 0.1-0.5, P=.02). Tumor size, site, age at diagnosis, and prior systemic therapy were not associated with response. The median time to first recurrence was 13.6 months. Those with CLL and age ?50 years at diagnosis had a shorter time to further treatment for local failures (hazard ratio [HR] 3.63, P=.01 and HR 5.50, P=.02, respectively). Those with CLL and MCL had a shorter time to further treatment for distant failures (HR 11.1 and 16.3, respectively, P<.0001). Conclusions: High local response rates were achieved with LD-IFRT across most histologies. Chronic lymphocytic leukemia and MCL histologies and age ?50 years at diagnosis had a shorter time to further treatment after LD-IFRT.

  18. Involvement of a eukaryotic-like ubiquitin-related modifier in the proteasome pathway of the archaeon Sulfolobus acidocaldarius

    E-Print Network [OSTI]

    Anjum, Rana S.; Bray, Sian M.; Blackwood, John K.; Kilkenny, Mairi L.; Coelho, Matthew A.; Foster, Benjamin M.; Li, Shurong; Howard, Julie A.; Pellegrini, Luca; Albers, Sonja-Verena; Deery, Michael J.; Robinson, Nicholas P.

    2015-01-01

    1 Involvement of a eukaryotic-like ubiquitin-related modifier in the proteasome pathway of the archaeon Sulfolobus acidocaldarius. Rana S. Anjum 1*, Sian M. Bray 1*, John K. Blackwood 1, Mairi L. Kilkenny 1, Matthew A. Coelho... , UK. 2) Cambridge Centre for Proteomics, Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, UK. 3) Molecular Biology of Archaea, Max Planck Institute for Terrestrial Microbiology, 35043...

  19. Future climate trends from a first-difference atmospheric carbon dioxide regression model involving emissions scenarios for business as usual and for peak fossil fuel

    E-Print Network [OSTI]

    Leggett, L M W

    2014-01-01

    This paper investigates the implications of the future continuation of the demonstrated past (1960-2012) strong correlation between first-difference atmospheric CO2 and global surface temperature. It does this, for the period from the present to 2050, for a comprehensive range of future global fossil fuel energy use scenarios. The results show that even for a business-as-usual (the mid-level IPCC) fossil fuel use estimate, global surface temperature will rise at a slower rate than for the recent period 1960-2000. Concerning peak fossil fuel, for the most common scenario the currently observed (1998-2013)temperature plateau will turn into a decrease. The observed trend to date for temperature is compared with that for global climate disasters: these peaked in 2005 and are notably decreasing. The temperature and disaster results taken together are consistent with either a reduced business-as-usual fossil fuel use scenario into the future, or a peak fossil fuel scenario, but not with the standard business-as-usu...

  20. The Effect of Parent School Involvement and Parent Perceptions about School on Children’s Perceived Academic Competence and Behavioral Engagement: A Mediational Model 

    E-Print Network [OSTI]

    Dede, Brandy Taylor

    2015-05-21

    . Non- demographic study variables ranged from -0.96 to 1.13 for skewness and -1.05 to 2.61 25 for kurtosis. According to Curran, West, and Finch (1996), these levels meet criteria for multivariate normality. Descriptive statistics...

  1. Modeling Quality Information within Business Process Models

    E-Print Network [OSTI]

    Paech, Barbara

    Modeling Quality Information within Business Process Models Robert Heinrich, Alexander Kappe. Business process models are a useful means to document information about structure and behavior literature and tool survey on modeling quality information within business process models. Keywords: Business

  2. Mathematical Model Reformulation for Lithium-Ion Battery Simulations: Galvanostatic Boundary Conditions

    E-Print Network [OSTI]

    Subramanian, Venkat

    Mathematical Model Reformulation for Lithium-Ion Battery Simulations: Galvanostatic Boundary of physics-based lithium-ion battery models to improve computational efficiency. While the additional steps, 2008. Published January 30, 2009. Mathematical modeling of lithium-ion batteries involves

  3. MicroScale Modeling of an AnodeSupported Planar Solid Oxide Fuel Cell

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    1 Micro­Scale Modeling of an Anode­Supported Planar Solid Oxide Fuel Cell P. Chinda1 , W. Wechsatol A micro ­ scale model of a Solid Oxide Fuel Cell (SOFC) involving the mass transfer together the available literatures. Keywords: Solid Oxide Fuel Cells, Micro ­ Scale Model, Mass Transfer, Electrochemical

  4. Biochimica et BiophysicaActa, 726 (1983) 265-292 265 MODEL REACTIONS IN PHOTOSYNTHESIS

    E-Print Network [OSTI]

    Boxer, Steven G.

    1983-01-01

    of this field from the particular perspective of attempts to model photosynthesis in artificial systems .................................................................................. 288 I. What are we trying to model? 1A. Introduction Photosynthesis involves a very large number. In addition, models in photosynthesis research play a prominent role in testing theoretical concepts

  5. A Model-driven Approach to Designing Cross-enterprise Business Processes

    E-Print Network [OSTI]

    Bauer, Bernhard

    A Model-driven Approach to Designing Cross- enterprise Business Processes Bernhard Bauer1, Jörg P.p.mueller@siemens.com Abstract. Modeling and managing business processes that span multiple or- ganizations involves new for interoperability. In this paper, we present an approach to modeling cross-enterprise business processes based

  6. Mesoscale modeling of electrical percolation in fiber-filled systems Sameer S. Rahatekar and Marc Hamm

    E-Print Network [OSTI]

    Elliott, James

    Mesoscale modeling of electrical percolation in fiber-filled systems Sameer S. Rahatekar and Marc online 4 October 2005 The research described in this paper primarily involves mesoscale simulations

  7. An Efficient Multiperiod MINLP Model for Optimal Planning of Offshore Oil and Gas Field Infrastructure

    E-Print Network [OSTI]

    Grossmann, Ignacio E.

    horizon, the model involves decisions related to FPSO (floating production, storage and offloading planning, FPSO * E-mail: vijaygup@andrew.cmu.edu To whom all correspondence should be addressed. E

  8. Statistical Modeling of Daily Energy Consumption in Commercial Buildings Using Multiple Regression and Principal Component Analysis 

    E-Print Network [OSTI]

    Reddy, T. A.; Claridge, D.; Wu, J.

    1992-01-01

    Statistical models of energy use in commercial buildings are being increasingly used not only for predicting retrofit savings but also for identifying improper operation of HVAC systems. The conventional approach involves using multiple regression...

  9. Measuring cognitive load management in a traditional martial arts training model 

    E-Print Network [OSTI]

    Maier, Herbert N.

    2005-08-29

    A training method utilized in a few martial arts was found to agree strongly with current cognitive psychology theory. Further study extracted a procedural model for learning a complex set of whole-body, dyadic motor skills involving high...

  10. CEE 812 Structural Engineering Seminar Series Modeling seismic isolation systems for critical

    E-Print Network [OSTI]

    Kamat, Vineet R.

    hazards. At much smaller scales, seismic qualification criteria for telecommunications equipment involvesCEE 812 ­ Structural Engineering Seminar Series Modeling seismic isolation systems for critical operations. The use of seismic isolation in the protection of these facilities is predicated upon

  11. Theory of ultra dense matter and the dynamics of high energy interactions involving nuclei. Progress report, December 15, 1993--December 14, 1994

    SciTech Connect (OSTI)

    Gyulassy, M.

    1994-09-12

    This report summarizes the progress made during the second year of the three year DOE agreement DE-FG02-93ER40764 on theoretical nuclear physics research performed at the Columbia University and presents a detailed budget adjustment for the third year period December 15, 1994 to December 14, 1995. Sections 1.1 to 1.8 highlight the technical progress made on the following general areas: Multiple scattering and radiative processes in QCD; the quark-gluon plasma transition in nuclear matter; QCD transport theory and dissipative mechanism in dense matter; phenomenological models of high energy interactions involving nuclei; signatures of quark-gluon plasma formation in A+A; neurocomputation theory. Section 2 contains a bibliography of published papers and invited conference papers. Section 3 lists the Columbia nuclear theory members for the December 15, 1994 to December 14, 1995 period. Finally, the budget adjustment requesting $319,830 for the third year relative to the original $320,000 is presented in section 6. Copies of the research papers accompany this report.

  12. GABA/sub B/ receptor activation inhibits Ca/sup 2 +/-activated potassium channels in synaptosomes: involvement of G-proteins

    SciTech Connect (OSTI)

    Ticku, M.K.; Delgado, A.

    1989-01-01

    /sup 86/Rb-efflux assay from preloaded synaptosomes of rat cerebral cortex was developed to study the effect of GABA/sub B/ receptor agonist baclofen on Ca/sup 2 +/-activated K/sup +/-channels. Depolarization of /sup 86/Rb-loaded synaptosomes in physiological buffer increased Ca/sup 2 +/-activated /sup 86/Rb-efflux by 400%. The /sup 86/Rb-efflux was blocked by quinine sulfate, tetraethylammonium, and La/sup 3 +/ indicating the involvement of Ca/sup 2 +/-activated K/sup +/-channels. (-)Baclofen inhibited Ca/sup 2 +/-activated /sup 86/Rb-efflux in a stereospecific manner. The inhibitory effect of (-)baclofen was mediated by GABA/sub B/ receptor activation, since it was blocked by GABA/sub B/ antagonist phaclofen, but not by bicuculline. Further, pertussis toxin also blocked the ability of baclofen or depolarizing action to affect Ca/sup 2 +/-activated K/sup +/-channels. These results suggest that baclofen inhibits Ca/sup 2 +/-activated K/sup +/-channels in synaptosomes and these channels are regulated by G-proteins. This assay may provide an ideal in vitro model to study GABA/sub B/ receptor pharmacology.

  13. Top decays in extended models

    SciTech Connect (OSTI)

    Gaitan, R.; Miranda, O. G.; Cabral-Rosetti, L. G.

    2009-04-20

    Top quark decays are interesting as a mean to test the Standard Model (SM) predictions. The Cabbibo-Kobayashi-Maskawa (CKM)-suppressed process t{yields}cWW, and the rare decays t{yields}cZ, t{yields}H{sup 0}+c, and t{yields}c{gamma} an excellent window to probe the predictions of theories beyond the SM. We evaluate the flavor changing neutral currents (FCNC) decay t{yields}H{sup 0}+c in the context of Alternative Left-Right symmetric Models (ALRM) with extra isosinglet heavy fermions; the FCNC decays may place at tree level and are only supressed by the mixing between ordinary top and charm quarks. We also comment on the decay process t{yields}c+{gamma}, which involves radiative corrections.

  14. The Yanks are Coming Over There: The Role of Anglo-Saxonism and American Involvement in the First World War

    E-Print Network [OSTI]

    Buenviaje, Dino Ejercito

    2014-01-01

    introduced the bondage of feudalism. This also coincidedcorrupted by Norman feudalism and continental absolutism. Bythe ideal model for the feudalism that was established since

  15. Cytoplasmic polyadenylation and cytoplasmic polyadenylation element-dependent mRNA regulation are involved in Xenopus retinal axon development

    E-Print Network [OSTI]

    Lin, Andrew C; Tan, Chin Lik; Lin, Chien-Ling; Strochlic, Laure; Huang, Yi-Shuian; Richter, Joel D; Holt, Christine E

    2009-03-02

    ) RFP/RBM-transfected embryos have bright RFP-positive axons in the optic pathway projecting correctly to the tectum, while RFP/AA-transfected embryos do not. Scale bars: 65 ?m (A, B, M, N); 10 ?m (D, F, J, K); 5 ?m (I). Blue, DAPI; green, CPEB1-GFP... AcceCResearch article Cytoplasmic polyadenylation and cytoplasmic polyadenylation element-dependent mRNA regulation are involved in Xenopus retinal axon development Andrew C Lin1,3, Chin Lik Tan1,4, Chien-Ling Lin2, Laure Strochlic1,5, Yi- Shuian...

  16. Characterization of the ptr5{sup +} gene involved in nuclear mRNA export in fission yeast

    SciTech Connect (OSTI)

    Watanabe, Nobuyoshi; Ikeda, Terumasa; Mizuki, Fumitaka [Department of Biological Sciences, Graduate School of Science and Technology, Kumamoto University, Kurokami, Kumamoto 860-8555 (Japan)] [Department of Biological Sciences, Graduate School of Science and Technology, Kumamoto University, Kurokami, Kumamoto 860-8555 (Japan); Tani, Tokio, E-mail: ttani@sci.kumamoto-u.ac.jp [Department of Biological Sciences, Graduate School of Science and Technology, Kumamoto University, Kurokami, Kumamoto 860-8555 (Japan)] [Department of Biological Sciences, Graduate School of Science and Technology, Kumamoto University, Kurokami, Kumamoto 860-8555 (Japan)

    2012-02-03

    Highlights: Black-Right-Pointing-Pointer We cloned the ptr5{sup +} gene involved in nuclear mRNA export in fission yeast. Black-Right-Pointing-Pointer The ptr5{sup +} gene was found to encode nucleoporin 85 (Nup85). Black-Right-Pointing-Pointer Seh1p and Mlo3p are multi-copy suppressors for the ptr5 mutation. Black-Right-Pointing-Pointer Ptr5p/Nup85p functions in nuclear mRNA export through the mRNA export factor Rae1p. Black-Right-Pointing-Pointer Ptr5p/Nup85p interacts genetically with pre-mRNA splicing factors. -- Abstract: To analyze the mechanisms of mRNA export from the nucleus to the cytoplasm, we have isolated eleven mutants, ptr [poly(A){sup +} RNA transport] 1 to 11, which accumulate poly(A){sup +} RNA in the nucleus at a nonpermissive temperature in Schizosaccharomyces pombe. Of those, the ptr5-1 mutant shows dots- or a ring-like accumulation of poly(A){sup +} RNA at the nuclear periphery after shifting to the nonpermissive temperature. We cloned the ptr5{sup +} gene and found that it encodes a component of the nuclear pore complex (NPC), nucleoporin 85 (Nup85). The ptr5-1 mutant shows no defects in protein transport, suggesting the specific involvement of Ptr5p/Nup85p in nuclear mRNA export in S. pombe. We identified Seh1p, a nucleoporin interacting with Nup85p, an mRNA-binding protein Mlo3p, and Sac3p, a component of the TREX-2 complex involved in coupling of nuclear mRNA export with transcription, as multi-copy suppressors for the ptr5-1 mutation. In addition, we found that the ptr5-1 mutation is synthetically lethal with a mutation of the mRNA export factor Rae1p, and that the double mutant exaggerates defective nuclear mRNA export, suggesting that Ptr5p/Nup85p is involved in nuclear mRNA export through Rae1p. Interestingly, the ptr5-1 mutation also showed synthetic effects with several prp pre-mRNA splicing mutations, suggesting a functional linkage between the NPCs and the splicing apparatus in the yeast nucleus.

  17. Abstract --Impaired lateral balance involving the frontal plane is particularly relevant to the problem of falls with aging.

    E-Print Network [OSTI]

    for the two types of stepping response. Our tool for these evaluations was a computational model of the center mathematical model of biomechanics and neural control is a promising way of differentiating behavior between) is with the Sensory Motor Performance Program, Rehabilitation Institute of Chicago, Physical Medicine & Rehabilitation

  18. Modelling osteomyelitis

    E-Print Network [OSTI]

    Liò, Pietro; Paoletti, Nicola; Moni, Mohammad A; Atwell, Kathryn; Merelli, Emanuela; Viceconti, Marco

    2012-09-07

    be: x < xmax ? ? : x = x + 1 x < xmin ? ? : x = x ? 1 where xmax and xmin are the maximum and the mini- mum x, resp. In other words, growth rates in the ODE model become the stochastic rates in a transition incre- menting the population size, while...

  19. Counting Problems involving Symmetry

    E-Print Network [OSTI]

    Donu Arapura

    2013-04-12

    Group theory can be applied to counting problems invloving symmetry. Here ... problem is to count the set of orbits H/S3. ... a partition of G. By corollary 3.10,.

  20. Counting Problems involving Symmetry*

    E-Print Network [OSTI]

    Group theory can be applied to counting problems invloving symmetry. Here ... problem is to count the set of orbits H/S3. .... a partition of G. By corollary 2.3,.

  1. Parent Involvement (Spanish) 

    E-Print Network [OSTI]

    Howard, Jeff W.

    2005-05-10

    Para que un programa de 4-Hh sea exitoso, debe contar con la participaci?n de los padres. Aunque los l?deres de 4-H y los agentes de Extensi?n pueden interesar a los j?venes en ser miembros, necesitan la buena voluntad de los padres y su apoyo para...?deres voluntarios, los agentes de Extensi?n y lo que los miembros del 4-H esperan. Cuando los padres participan solamente super- ficialmente y no se les informa sobre las actividades del club, se puede esperar poca cooperaci?n de ellos. Se debe informar a los...

  2. Commitment to Public Involvement

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity ofkandz-cm11 Outreach Home Room News PublicationsAuditsCluster Compatibilitydefault Sign In About | Careers |Create a

  3. TPA Public Involvement Survey

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power AdministrationRobust,Field-effectWorking With LivermoreSustainableDEPARTMENT OFEnergy Innovation

  4. Involvement & Outreach

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantity of NaturalDukeWakefieldSulfateSciTechtail.Theory ofDid you notHeat Pumps Heat PumpsfacilityviaGasforVendors »

  5. Involvement and Communication Committee.

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverseIMPACT EVALUATIONIntroducing the RichardBudget and Contracts Committee Chair 1

  6. Involvement and Communication Committee.

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverseIMPACT EVALUATIONIntroducing the RichardBudget and Contracts Committee Chair

  7. Involvement and Communication Committee.

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverseIMPACT EVALUATIONIntroducing the RichardBudget and Contracts Committee

  8. Involvement and Communication Committee.

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverseIMPACT EVALUATIONIntroducing the RichardBudget and Contracts CommitteeRiver

  9. Involvement and Communication Committee.

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverseIMPACT EVALUATIONIntroducing the RichardBudget and Contracts

  10. Criticality Model

    SciTech Connect (OSTI)

    A. Alsaed

    2004-09-14

    The ''Disposal Criticality Analysis Methodology Topical Report'' (YMP 2003) presents the methodology for evaluating potential criticality situations in the monitored geologic repository. As stated in the referenced Topical Report, the detailed methodology for performing the disposal criticality analyses will be documented in model reports. Many of the models developed in support of the Topical Report differ from the definition of models as given in the Office of Civilian Radioactive Waste Management procedure AP-SIII.10Q, ''Models'', in that they are procedural, rather than mathematical. These model reports document the detailed methodology necessary to implement the approach presented in the Disposal Criticality Analysis Methodology Topical Report and provide calculations utilizing the methodology. Thus, the governing procedure for this type of report is AP-3.12Q, ''Design Calculations and Analyses''. The ''Criticality Model'' is of this latter type, providing a process evaluating the criticality potential of in-package and external configurations. The purpose of this analysis is to layout the process for calculating the criticality potential for various in-package and external configurations and to calculate lower-bound tolerance limit (LBTL) values and determine range of applicability (ROA) parameters. The LBTL calculations and the ROA determinations are performed using selected benchmark experiments that are applicable to various waste forms and various in-package and external configurations. The waste forms considered in this calculation are pressurized water reactor (PWR), boiling water reactor (BWR), Fast Flux Test Facility (FFTF), Training Research Isotope General Atomic (TRIGA), Enrico Fermi, Shippingport pressurized water reactor, Shippingport light water breeder reactor (LWBR), N-Reactor, Melt and Dilute, and Fort Saint Vrain Reactor spent nuclear fuel (SNF). The scope of this analysis is to document the criticality computational method. The criticality computational method will be used for evaluating the criticality potential of configurations of fissionable materials (in-package and external to the waste package) within the repository at Yucca Mountain, Nevada for all waste packages/waste forms. The criticality computational method is also applicable to preclosure configurations. The criticality computational method is a component of the methodology presented in ''Disposal Criticality Analysis Methodology Topical Report'' (YMP 2003). How the criticality computational method fits in the overall disposal criticality analysis methodology is illustrated in Figure 1 (YMP 2003, Figure 3). This calculation will not provide direct input to the total system performance assessment for license application. It is to be used as necessary to determine the criticality potential of configuration classes as determined by the configuration probability analysis of the configuration generator model (BSC 2003a).

  11. Purely Mechanical Memristors: Perfect Massless Memory Resistors, the Missing Perfect Mass-Involving Memristor, and Massive Memristive Systems

    E-Print Network [OSTI]

    Sascha Vongehr

    2015-08-15

    We define a mechanical analog to the electrical basic circuit element M = d{\\phi}/dQ, namely the ideal mechanical memristance M = dp/dx; p is momentum. We then introduce a mechanical memory resistor which has M(x) independent of velocity v, so it is a perfect (= not-just-memristive) memristor, although its memristance does not crucially involve inert mass. It is practically realizable with a 1cm radius hollow sphere in heavy fuel oil with a temperature gradient. It has a pinched hysteretic loop that collapses at high frequency in the v versus p plot. The mechanical system clarifies the nature of memristor devices that can be hypothesized on grounds of physical symmetries. We hypothesize a missing mechanical perfect memristor, which must be crucially mass-involving (MI) precisely like the 1971 implied EM memristor device needs magnetism. We also construct MI memristive nano systems, which clarifies why perfect MI memristors and EM memristors are still missing and likely impossible.

  12. MODELING HUMAN RELIABILITY ANALYSIS USING MIDAS

    SciTech Connect (OSTI)

    Ronald L. Boring; Donald D. Dudenhoeffer; Bruce P. Hallbert; Brian F. Gore

    2006-05-01

    This paper summarizes an emerging collaboration between Idaho National Laboratory and NASA Ames Research Center regarding the utilization of high-fidelity MIDAS simulations for modeling control room crew performance at nuclear power plants. The key envisioned uses for MIDAS-based control room simulations are: (i) the estimation of human error with novel control room equipment and configurations, (ii) the investigative determination of risk significance in recreating past event scenarios involving control room operating crews, and (iii) the certification of novel staffing levels in control rooms. It is proposed that MIDAS serves as a key component for the effective modeling of risk in next generation control rooms.

  13. Nuclear Models

    SciTech Connect (OSTI)

    Fossion, Ruben [Instituto de Ciencias Nucleares, Universidad Nacional Autonoma de Mexico, Apartado Postal 70-543, Mexico D. F., C.P. 04510 (Mexico)

    2010-09-10

    The atomic nucleus is a typical example of a many-body problem. On the one hand, the number of nucleons (protons and neutrons) that constitute the nucleus is too large to allow for exact calculations. On the other hand, the number of constituent particles is too small for the individual nuclear excitation states to be explained by statistical methods. Another problem, particular for the atomic nucleus, is that the nucleon-nucleon (n-n) interaction is not one of the fundamental forces of Nature, and is hard to put in a single closed equation. The nucleon-nucleon interaction also behaves differently between two free nucleons (bare interaction) and between two nucleons in the nuclear medium (dressed interaction).Because of the above reasons, specific nuclear many-body models have been devised of which each one sheds light on some selected aspects of nuclear structure. Only combining the viewpoints of different models, a global insight of the atomic nucleus can be gained. In this chapter, we revise the the Nuclear Shell Model as an example of the microscopic approach, and the Collective Model as an example of the geometric approach. Finally, we study the statistical properties of nuclear spectra, basing on symmetry principles, to find out whether there is quantum chaos in the atomic nucleus. All three major approaches have been rewarded with the Nobel Prize of Physics. In the text, we will stress how each approach introduces its own series of approximations to reduce the prohibitingly large number of degrees of freedom of the full many-body problem to a smaller manageable number of effective degrees of freedom.

  14. The Minimal Supersymmetric Fat Higgs Model

    SciTech Connect (OSTI)

    Harnik, Roni; Kribs, Graham D.; Larson, Daniel T.; Murayama, Hitoshi

    2003-11-26

    We present a calculable supersymmetric theory of a composite"fat'" Higgs boson. Electroweak symmetry is broken dynamically through a new gauge interaction that becomes strong at an intermediate scale. The Higgs mass can easily be 200-450 GeV along with the superpartner masses, solving the supersymmetric little hierarchy problem. We explicitly verify that the model is consistent with precision electroweak data without fine-tuning. Gauge coupling unification can be maintained despite the inherently strong dynamics involved in electroweak symmetry breaking. Supersymmetrizing the Standard Model therefore does not imply a light Higgs mass, contrary to the lore in the literature. The Higgs sector of the minimal Fat Higgs model has a mass spectrum that is distinctly different from the Minimal Supersymmetric Standard Model.

  15. DOE Technical Standards List. Directory of DOE and contractor personnel involved in non-government standards activities

    SciTech Connect (OSTI)

    NONE

    1997-06-01

    This is a periodic report on the level of agency participation in non-Government standards activities. This technical standards list is intended to assist US Department of Energy (DOE) management and other personnel involved in the DOE technical Standards Program by identifying those participating individuals. The body of this document contains a listing of DOE employees and DOE contractors who have submitted a Record of Non-Government Standards Activity. Additional names were added from rosters supplied by non-Government standards bodies. Appendices to this document are provided to list the information by parent employment organization, by non-Government standards activity, and by the proper names of the non-Government standards organizations and committees.

  16. DNA rearrangement in human follicular lymphoma can involve the 5' or the 3' region of the bcl-2 gene

    SciTech Connect (OSTI)

    Tsujimoto, Y.; Bashir, M.M.; Givol, I.; Cossman, J.; Jaffe, E.; Croce, C.M.

    1987-03-01

    In most human lymphomas, the chromosome translocation t(14;18) occurs within two breakpoint clustering regions on chromosome 18, the major one at the 3' untranslated region of the bcl-2 gene and the minor one at 3' of the gene. Analysis of a panel of follicular lymphoma DNAs using probes for the first exon of the bcl-2 gene indicates that DNA rearrangements may also occur 5' to the involved bcl-2 gene. In this case the IgH locus and the bcl-2 gene are found in an order suggesting that an inversion also occurred during the translocation process. The coding region of the bcl-2 gene, however, are left intact in all cases of follicular lymphoma studied to date.

  17. SECURITY MODELING FOR MARITIME PORT DEFENSE RESOURCE ALLOCATION

    SciTech Connect (OSTI)

    Harris, S.; Dunn, D.

    2010-09-07

    Redeployment of existing law enforcement resources and optimal use of geographic terrain are examined for countering the threat of a maritime based small-vessel radiological or nuclear attack. The evaluation was based on modeling conducted by the Savannah River National Laboratory that involved the development of options for defensive resource allocation that can reduce the risk of a maritime based radiological or nuclear threat. A diverse range of potential attack scenarios has been assessed. As a result of identifying vulnerable pathways, effective countermeasures can be deployed using current resources. The modeling involved the use of the Automated Vulnerability Evaluation for Risks of Terrorism (AVERT{reg_sign}) software to conduct computer based simulation modeling. The models provided estimates for the probability of encountering an adversary based on allocated resources including response boats, patrol boats and helicopters over various environmental conditions including day, night, rough seas and various traffic flow rates.

  18. Comprehensive computer model for magnetron sputtering. II. Charged particle transport

    SciTech Connect (OSTI)

    Jimenez, Francisco J., E-mail: fjimenez@ualberta.ca; Dew, Steven K. [Department of Electrical and Computer Engineering, University of Alberta, Edmonton T6G 2V4 (Canada); Field, David J. [Smith and Nephew (Alberta) Inc., Fort Saskatchewan T8L 4K4 (Canada)

    2014-11-01

    Discharges for magnetron sputter thin film deposition systems involve complex plasmas that are sensitively dependent on magnetic field configuration and strength, working gas species and pressure, chamber geometry, and discharge power. The authors present a numerical formulation for the general solution of these plasmas as a component of a comprehensive simulation capability for planar magnetron sputtering. This is an extensible, fully three-dimensional model supporting realistic magnetic fields and is self-consistently solvable on a desktop computer. The plasma model features a hybrid approach involving a Monte Carlo treatment of energetic electrons and ions, along with a coupled fluid model for thermalized particles. Validation against a well-known one-dimensional system is presented. Various strategies for improving numerical stability are investigated as is the sensitivity of the solution to various model and process parameters. In particular, the effect of magnetic field, argon gas pressure, and discharge power are studied.

  19. Selection of potential IAEA inspection strategies involving cascade access at the Portsmouth Gas Centrifuge Enrichment Plant (GCEP)

    SciTech Connect (OSTI)

    Not Available

    1981-04-13

    This report has been prepared as a US contribution to Team 4 of the Hexapartite Safeguards Project. It provides to the Team 4 participants one example of an approach, which has been used in the United States, to developing a range of safeguards strategies involving differing degrees of access to cascade areas of centrifuge enrichment plants. Its purpose is to facilitate the work of other Hexapartite participants in completing Task II of Team 4's terms of reference. The scope of this report is limited to identifying safeguards approaches for the Portsmouth Gas Centrifuge Enrichment Plant (GCEP) which involve differing degrees of access to the cascade area. This report provides a method for selecting cascade access inspection strategies at GCEP which appear promising for more detailed evaluation. It is quite important to note, however, that the effectiveness and practicability of these strategies have not been established at the present. In addition, some strategies have been included on the basis of very preliminary calculations and considerations which have not been validated. Thus, some of these strategies may ultimately be rejected because they prove to be impracticable. Considerations of cost and the possible transfer of information and technology related to the production of enriched uranium will also be pertinent in considering the degrees and frequency of access to the cascade areas of centrifuge enrichment plants. This report describes the process for combining technical measures, implementation approaches and objectives to arrive at the total number of theoretically possible combinations. It then describes how these combinations may be reduced in a series of steps to a number that is more manageable for detailed evaluation. The process is shown schematically.

  20. Involvement of caspase-12-dependent apoptotic pathway in ionic radiocontrast urografin-induced renal tubular cell injury

    SciTech Connect (OSTI)

    Wu, Cheng Tien [Institute of Toxicology, College of Medicine, National Taiwan University, Taipei, Taiwan (China)] [Institute of Toxicology, College of Medicine, National Taiwan University, Taipei, Taiwan (China); Weng, Te I. [Department of Forensic Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan (China)] [Department of Forensic Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan (China); Chen, Li Ping [Department of Dentistry, Chang Gang Memorial Hospital, Chang Gang University, Taoyuan, Taiwan (China)] [Department of Dentistry, Chang Gang Memorial Hospital, Chang Gang University, Taoyuan, Taiwan (China); Chiang, Chih Kang [Department of Integrated Diagnostics and Therapeutics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan (China) [Department of Integrated Diagnostics and Therapeutics, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan (China); Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan (China); Liu, Shing Hwa, E-mail: shinghwaliu@ntu.edu.tw [Institute of Toxicology, College of Medicine, National Taiwan University, Taipei, Taiwan (China); Department of Urology, National Taiwan University Hospital, Taipei, Taiwan (China)

    2013-01-01

    Contrast medium (CM) induces a direct toxic effect on renal tubular cells. This toxic effect subjects in the disorder of CM-induced nephropathy. Our previous work has demonstrated that CM shows to activate the endoplasmic reticulum (ER)-related adaptive unfolding protein response (UPR) activators. Glucose-regulated protein 78 (GRP78)/eukaryotic initiation factor 2? (eIF2?)-related pathways play a protective role during the urografin (an ionic CM)-induced renal tubular injury. However, the involvement of ER stress-related apoptotic signals in the urografin-induced renal tubular cell injury remains unclear. Here, we examined by the in vivo and in vitro experiments to explore whether ER stress-regulated pro-apoptotic activators participate in urografin-induced renal injury. Urografin induced renal tubular dilation, tubular cells detachment, and necrosis in the kidneys of rats. The tubular apoptosis, ER stress-related pro-apoptotic transcriptional factors, and kidney injury marker-1 (kim-1) were also conspicuously up-regulated in urografin-treated rats. Furthermore, treatment of normal rat kidney (NRK)-52E tubular cells with urografin augmented the expressions of activating transcription factor-6 (ATF-6), C/EBP homologous protein (CHOP), Bax, caspase-12, JNK, and inositol-requiring enzyme (IRE) 1 signals. Urografin-induced renal tubular cell apoptosis was not reversed by the inhibitors of ATF-6, JNK signals or CHOP siRNA transfection, but it could be partially reversed by the inhibitor of caspase-12. Taken together, the present results and our previous findings suggest that exposure of CM/urografin activates the ER stress-regulated survival- and apoptosis-related signaling pathways in renal tubular cells. Caspase-12-dependent apoptotic pathway may be partially involved in the urografin-induced nephropathy. -- Highlights: ? Ionic contrast medium-urografin induces renal tubular cell apoptosis. ? Urografin induces the ER stress-regulated survival and apoptosis signals. ? Caspase-12 signaling participates in urografin-induced renal cell apoptosis.

  1. Methodology for Modeling Building Energy Performance across the Commercial Sector

    SciTech Connect (OSTI)

    Griffith, B.; Long, N.; Torcellini, P.; Judkoff, R.; Crawley, D.; Ryan, J.

    2008-03-01

    This report uses EnergyPlus simulations of each building in the 2003 Commercial Buildings Energy Consumption Survey (CBECS) to document and demonstrate bottom-up methods of modeling the entire U.S. commercial buildings sector (EIA 2006). The ability to use a whole-building simulation tool to model the entire sector is of interest because the energy models enable us to answer subsequent 'what-if' questions that involve technologies and practices related to energy. This report documents how the whole-building models were generated from the building characteristics in 2003 CBECS and compares the simulation results to the survey data for energy use.

  2. PHENOMENOLOGY Wireless Channel Modeling

    E-Print Network [OSTI]

    Giridhar, K.

    PHENOMENOLOGY Wireless Channel Modeling Clarke's, Jakes' and modified Jakes' models Koyalkar Raman? What is channel modeling? Wireless channel modeling Modeling Fading ­ Rayleigh Clarke's, Jakes, they are short ranged, motion restricted. Channel Wired - Single Path - Motion Restricted Wireless - Multipath

  3. Models Datasets

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration wouldMass map shines light on77 PAGEMission MissionModeling distributed generation in8 May

  4. ISDAC Modeling

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Homesum_a_epg0_fpd_mmcf_m.xls" ,"Available from WebQuantityBonneville Power Administration would likeUniverse (JournalvivoHighHussein KhalilResearch88 Sign In About | WorkshopModeling

  5. IEOR 6711: Stochastic Models I Fall 2014, Professor Whitt

    E-Print Network [OSTI]

    Whitt, Ward

    IEOR 6711: Stochastic Models I Fall 2014, Professor Whitt Topics for Discussion: Thursday, October 9 The Renewal Equation, the Renewal Function and the Renewal Theorems Renewal theory involves only a few key ideas. First, renewal theory is about renewal processes. A key quantity is the renewal

  6. Neural network model of creep strength of austenitic stainless steels

    E-Print Network [OSTI]

    Cambridge, University of

    Neural network model of creep strength of austenitic stainless steels T. Sourmail, H. K. D. H, and solution treatment temperature. The method involved a neural network analysis of a vast and general, and stress. Neural networks represent a more general regression method, which ameliorates most

  7. Model hydrocracking reactions over monometallic and bimetallic dispersed catalysts

    SciTech Connect (OSTI)

    Schmidt, E.; Song, C. [Penn State Univ., University Park, PA (United States)

    1994-12-31

    Coal liquefaction involves the cleavage of methylene and dimethylene bridges connecting polycyclic aromatic units. The selected compound for model reactions is 4-(1-naphthylmethyl)bibenzyl (NMBB). This work describes the synthesis and screening of several metallic complex precursors as dispersed catalysts for hydrocracking of NMBB.

  8. Realistic shell-model calculations: current status and open problems

    E-Print Network [OSTI]

    A. Covello; A. Gargano

    2010-03-29

    The main steps involved in realistic shell-model calculations employing two-body low-momentum interactions are briefly reviewed. The practical value of this approach is exemplified by the results of recent calculations and some remaining open questions and directions for future research are discussed.

  9. Continuous time Markov chain models for chemical reaction networks

    E-Print Network [OSTI]

    Kurtz, Tom

    Continuous time Markov chain models for chemical reaction networks David F. Anderson Departments Abstract A reaction network is a chemical system involving multiple reactions and chemical species exploit the representation of the stochastic equation for chemical reaction networks and, under what

  10. Modeling of a detonation driven, linear electric generator facility

    E-Print Network [OSTI]

    Texas at Arlington, University of

    Modeling of a detonation driven, linear electric generator facility E.M. Braun, E. Baydar, and F demonstrated that a PDE can be used for power generation and may be more efficient than a deflagration that involve coupling a PDE with different systems to drive a generator and produce electricity [2, 3]. One

  11. Modeling Blast Loading on Buried Reinforced Concrete Structures with Zapotec

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Bessette, Greg C.

    2008-01-01

    A coupled Euler-Lagrange solution approach is used to model the response of a buried reinforced concrete structure subjected to a close-in detonation of a high explosive charge. The coupling algorithm is discussed along with a set of benchmark calculations involving detonations in clay and sand.

  12. Model-Based Dependability Analysis of Programmable Drug Infusion Pumps

    E-Print Network [OSTI]

    Sankaranarayanan, Sriram

    Model-Based Dependability Analysis of Programmable Drug Infusion Pumps Sriram Sankaranarayanan.lastname@colorado.edu Abstract. Infusion pumps are commonly used in home/hospital care to inject drugs into a patient a case-study involving an infusion pump used to manage pain through the infusion of analgesic drugs

  13. TEPP Planning Products Model Needs Assessment Self Assessment...

    Office of Environmental Management (EM)

    used in the event of an incident involving safeguards material. Model Needs Assessment T r a n s p o r t a t i o n E m e r g e n c y P r e p a r e d n e s s P r o g r a m R E V 8...

  14. Modeling rf breakdown arcs II: plasma / materials interactions

    E-Print Network [OSTI]

    Insepov, Zeke; Proslier, Thomas; Mahalingam, Sudhakar; Veitzer, S

    2010-01-01

    Continuing the description of rf vacuum arcs from an earlier paper, we describe some aspects of the interaction of vacuum arcs that involve the surface. This paper describes aspects of plasma materials interactions that affect the arc and models measurement of the surface field using the Tonks-Frenkel and the spinodal electrohydrodynamic instabilities, a realistic model for the generation and evaluation of high field enhancements, unipolar arcs, creep and other effects.

  15. Protein Structure Modeling With MODELLER Narayanan Eswar$

    E-Print Network [OSTI]

    Sali, Andrej

    of MODELLER to construct a comparative model for a protein with unknown structure. Automation of similar se- quence and the template(s); (iii) building a model based on the alignment with the cho- sen user intervention and within minutes on a desktop computer. Apart from model building, MODELLER can

  16. Multivariate Receptor Models and Model Uncertainty

    E-Print Network [OSTI]

    Washington at Seattle, University of

    Multivariate Receptor Models and Model Uncertainty Eun Sug Park Man-Suk Oh Peter Guttorp NRCSET e c provides the Center's primary funding. #12;Multivariate Receptor Models and Model Uncertainty Eun Sug Park1 composition profiles, and the source contributions is the main interest in multivariate receptor modeling. Due

  17. ccsd-00085042,version1-11Jul2006 A Two-dimensional eddy current model using thin

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    ccsd-00085042,version1-11Jul2006 A Two-dimensional eddy current model using thin inductors Youcef a mathematical model for eddy currents in two dimensional geometries where the conductors are thin domains. We Mathematical modelling of eddy current problems often involves multiple conductors with various sizes

  18. Seismic surface waves and associated phenomena in a system involving a shallow, thin, high-velocity layer 

    E-Print Network [OSTI]

    Egar, Joseph Michael

    1959-01-01

    systems installed in commercial buildings. A large prototypical office building (124,000 ft2) was used in simulation modeling. The DOE-2.1e program was used for whole building simulation, F-Chart (Beckman et al., 1977) for solar thermal systems... analysis, and PV F-Chart (Klein and Beckman, 1983) for solar PV systems analysis. INTRODUCTION This study is an extension of previous research. The preceding studies were (1) development of a detailed calibrated simulation model for a large office...

  19. Novel mechanism for scavenging of hypochlorite involving a periplasmic methionine-rich peptide and methionine sulfoxide reductase

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Melnyk, Ryan A.; Youngblut, Matthew D.; Clark, Iain C.; Carlson, Hans K.; Wetmore, Kelly M.; Price, Morgan N.; Lavarone, Anthony T.; Deutschbauer, Adam M.; Arkin, Adam P.; Coates, John D.

    2015-05-12

    Reactive chlorine species (RCS) defense mechanisms are important for bacterial fitness in diverse environments. In addition to the anthropogenic use of RCS in the form of bleach, these compounds are also produced naturally through photochemical reactions of natural organic matter and in vivo by the mammalian immune system in response to invading microorganisms. To gain insight into bacterial RCS defense mechanisms, we investigated Azospira suillum strain PS, which produces periplasmic RCS as an intermediate of perchlorate respiration. Our studies identified an RCS response involving an RCS stress-sensing sigma/anti-sigma factor system (SigF/NrsF), a soluble hypochlorite-scavenging methionine-rich periplasmic protein (MrpX), and amore »putative periplasmic methionine sulfoxide reductase (YedY1). We investigated the underlying mechanism by phenotypic characterization of appropriate gene deletions, chemogenomic profiling of barcoded transposon pools, transcriptome sequencing, and biochemical assessment of methionine oxidation. Our results demonstrated that SigF was specifically activated by RCS and initiated the transcription of a small regulon centering around yedY1 and mrpX. A yedY1 paralog (yedY2) was found to have a similar fitness to yedY1 despite not being regulated by SigF. Markerless deletions of yedY2 confirmed its synergy with the SigF regulon. MrpX was strongly induced and rapidly oxidized by RCS, especially hypochlorite. Our results suggest a mechanism involving hypochlorite scavenging by sacrificial oxidation of the MrpX in the periplasm. Reduced MrpX is regenerated by the YedY methionine sulfoxide reductase activity. The phylogenomic distribution of this system revealed conservation in several Proteobacteria of clinical importance, including uropathogenic Escherichia coli and Brucella spp., implying a putative role in immune response evasion in vivo. In addition, bacteria are often stressed in the environment by reactive chlorine species (RCS) of either anthropogenic or natural origin, but little is known of the defense mechanisms they have evolved. Using a microorganism that generates RCS internally as part of its respiratory process allowed us to uncover a novel defense mechanism based on RCS scavenging by reductive reaction with a sacrificial methionine-rich peptide and redox recycling through a methionine sulfoxide reductase. This system is conserved in a broad diversity of organisms, including some of clinical importance, invoking a possible important role in innate immune system evasion.« less

  20. Projecting Fatalities in Crashes Involving Older Drivers, 2000–2025, CRADA No. ORNL98-0500 Final Report

    SciTech Connect (OSTI)

    Hu, Patricia S. [ORNL] [ORNL; Jones, Donald W. [ORNL] [ORNL; Reuscher, Timothy [Oak Ridge Institute for Science and Education] [Oak Ridge Institute for Science and Education; Schmoyer, Richard S. [ORNL] [ORNL; Truett, Lorena F. [ORNL] [ORNL

    2000-04-01

    At the turn of the century – the 20th century that is – the median age in the United States was under 30 years; America was 60% rural in nature; and there were only 36 highway fatalities all year. As we leave the 20th century behind, the route into the 21st century is very different. “Intelligent” cars speed down multi-lane “smart” highways in a nation that is 75% urban. According to the Federal Highway Administration’s Highway Statistics, there are 28,000 times more vehicles on the road in 2000 than there were in 1900, and these vehicles travel about 2.6 trillion miles each year. Annual fatalities resulting from highway crashes have also increased – by over 1100%. We see other changes as well. The face of America is changing. It is growing older. In 2025, persons 65 and over will make up 18.5% of the total population. The number of persons aged 85 and over is increasing more rapidly than any other age group. More importantly, the elderly are taking more trips, driving further, and continuing to drive much later in life. These conditions lead to concerns about traffic safety. Although the elderly are healthier and drive safer cars than they did just two decades ago, their frailty makes them more susceptible to injury than younger persons involved in traffic crashes of the same severity. In addition, visual, physical, and cognitive skills, all of which contribute to driving abilities, decrease with advancing age. The familiar “U”-shaped curve depicting the rate of fatalities per vehicle miles traveled, shows that the elderly experience a higher highway fatality rate than any other age group except teenagers. While the overall number of highway fatalities has decreased regularly since 1972, the number of fatalities of elderly travelers has continued to increase steadily. This increase is cause for concern for both the elderly driver and for other persons on the roads who migh tbe placed in danger through crashes involving elderly drivers.

  1. Second-order model selection in mixture experiments

    SciTech Connect (OSTI)

    Redgate, P.E.; Piepel, G.F.; Hrma, P.R.

    1992-07-01

    Full second-order models for q-component mixture experiments contain q(q+l)/2 terms, which increases rapidly as q increases. Fitting full second-order models for larger q may involve problems with ill-conditioning and overfitting. These problems can be remedied by transforming the mixture components and/or fitting reduced forms of the full second-order mixture model. Various component transformation and model reduction approaches are discussed. Data from a 10-component nuclear waste glass study are used to illustrate ill-conditioning and overfitting problems that can be encountered when fitting a full second-order mixture model. Component transformation, model term selection, and model evaluation/validation techniques are discussed and illustrated for the waste glass example.

  2. An Agent-Based Modeling for Pandemic Influenza in Egypt

    E-Print Network [OSTI]

    Khalil, Khaled M; Nazmy, Taymour T; Salem, Abdel-Badeeh M

    2010-01-01

    Pandemic influenza has great potential to cause large and rapid increases in deaths and serious illness. The objective of this paper is to develop an agent-based model to simulate the spread of pandemic influenza (novel H1N1) in Egypt. The proposed multi-agent model is based on the modeling of individuals' interactions in a space time context. The proposed model involves different types of parameters such as: social agent attributes, distribution of Egypt population, and patterns of agents' interactions. Analysis of modeling results leads to understanding the characteristics of the modeled pandemic, transmission patterns, and the conditions under which an outbreak might occur. In addition, the proposed model is used to measure the effectiveness of different control strategies to intervene the pandemic spread.

  3. Data Models Avi Silberschatz

    E-Print Network [OSTI]

    Silberschatz, Avi

    . The various data models that have been proposed fall into three di erent groups: object-based logical models, record-based logical models, and physical data models. Physical data models are used to describe data models. Object-based logical models provide exible structuring capabilities and allow data constraints

  4. SEER Forward Plan for 2013/2014 The SEER project involves understanding a number of natural and human systems which

    E-Print Network [OSTI]

    Bateman, Ian J.

    ; impacts upon water quality; impacts on carbon balance and greenhouse gas emissions; land use effects of natural and human systems which are related to changes to land use. These systems include the drivers bringing together natural and social science models. Methodological improvements in the valuation

  5. Accurate Computer Simulation of Phase Equilibrium for Complex Fluid Mixtures. Application to Binaries Involving Isobutene, Methanol, Methyl tert-Butyl Ether, and

    E-Print Network [OSTI]

    Lisal, Martin

    to Binaries Involving Isobutene, Methanol, Methyl tert-Butyl Ether, and n-Butane Martin Li´sal,*,, William R + methyl tert-butyl ether (MTBE) and the binaries formed by methanol with isobutene, MTBE, and n

  6. University of Twente Scientific Integrity Complaints Procedure Within the University of Twente all persons involved in education and research have a personal

    E-Print Network [OSTI]

    Boucherie, Richard J.

    (the suspicion of) a violation of scientific integrity by an employee Complainant: A person whoUniversity of Twente Scientific Integrity Complaints Procedure Preamble Within the University of Twente all persons involved in education and research have a personal responsibility

  7. Modeling Traffic Flow Emissions

    E-Print Network [OSTI]

    Cappiello, Alessandra

    2002-09-17

    The main topic of this thesis is the development of light-duty vehicle dynamic emission models and their integration with dynamic traffic models. Combined, these models

  8. Sandia Energy - Phenomenological Modeling

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Phenomenological Modeling Home Stationary Power Nuclear Fuel Cycle Nuclear Energy Safety Technologies Phenomenological Modeling Phenomenological ModelingTara Camacho-Lopez2015-05-1...

  9. Visible light stimulating dual-wavelength emission and O vacancy involved energy transfer behavior in luminescence for coaxial nanocable arrays

    SciTech Connect (OSTI)

    Yang, Lei, E-mail: nanoyang@qq.com [College of Materials Science and Engineering, Hunan University, Changsha 410082 (China); Hunan Province Key Laboratory for Spray Deposition Technology and Application, Hunan University, Changsha 410082 (China); Dong, Jiazhang; Jiang, Zhongcheng [College of Materials Science and Engineering, Hunan University, Changsha 410082 (China); Pan, Anlian; Zhuang, Xiujuan [Key Laboratory for Micro-Nano Physics and Technology of Hunan Province, Hunan University, Changsha 410082 (China)

    2014-06-14

    We report a strategy to investigate O vacancy (V{sub O}) involved energy transfer and dual-wavelength yellow emission in coaxial nanocable. By electric field deposition and subsequent sol-gel template approach, ZnO:Tb/Y{sub 2}O{sub 3}:Eu coaxial nanocable arrays are synthesized. After visible light excitation, system is promoted to O vacancy charge transfer state of V{sub O}(0/+). In the following cross relaxation, energy transfer from V{sub O} to the excitation energy level of Tb{sup 3+} in ZnO:Tb core area. While in Y{sub 2}O{sub 3}:Eu shell area, energy transfer to the excitation energy level of Eu{sup 3+}. Subsequently, dual-wavelength emission is observed. By constructing nanocable with dual-wavelength emission, yellow luminescence is obtained. Adjust doping concentration of Eu{sup 3+} or Tb{sup 3+} in the range of 0.01–0.05, chromaticity coordinates of ZnO:Tb/Y{sub 2}O{sub 3}:Eu nanocable stably stays at yellow region in color space except ZnO:Tb{sub 0.01}/Y{sub 2}O{sub 3}:Eu{sub 0.01}. As Vo states act as media in energy transfer process in nanocablers, visible light can stimulate dual-wavelength emissions. Yellow luminescent nanocable arrays will have great applications in light-emitting diode luminescence.

  10. Bottomonium spectroscopy and radiative transitions involving the chi_bJ(1P,2P) states at BABAR

    E-Print Network [OSTI]

    J. P. Lees; for the BABAR Collaboration

    2014-10-16

    We use $(121\\pm1)$ million $\\Upsilon(3S)$ and $(98\\pm1)$ million $\\Upsilon(2S)$ mesons recorded by the BABAR detector at the PEP-II $e^+e^-$ collider at SLAC to perform a study of radiative transitions involving the $\\chi_{b\\mathrm{J}}(1P,2P)$ states in exclusive decays with $\\mu^+\\mu^-\\gamma\\gamma$ final states. We reconstruct twelve channels in four cascades using two complementary methods. In the first we identify both signal photon candidates in the Electromagnetic Calorimeter (EMC), employ a calorimeter timing-based technique to reduce backgrounds, and determine branching-ratio products and fine mass splittings. These results include the best observational significance yet for the $\\chi_{b0}(2P)\\rightarrow\\gamma\\Upsilon(2S)$ and $\\chi_{b0}(1P)\\rightarrow\\gamma\\Upsilon(1S)$ transitions. In the second method, we identify one photon candidate in the EMC and one which has converted into an $e^+e^-$ pair due to interaction with detector material, and we measure absolute product branching fractions. This method is particularly useful for measuring $\\Upsilon(3S)\\rightarrow\\gamma\\chi_{b1,2}(1P)$ decays. Additionally, we provide the most up-to-date derived branching fractions, matrix elements and mass splittings for $\\chi_b$ transitions in the bottomonium system. Using a new technique, we also measure the two lowest-order spin-dependent coefficients in the nonrelativistic QCD Hamiltonian.

  11. G-protein-coupled estrogen receptor 1 is involved in brain development during zebrafish (Danio rerio) embryogenesis

    SciTech Connect (OSTI)

    Shi, Yanan; Liu, Xiaochun; Zhu, Pei; Li, Jianzhen; Sham, Kathy W.Y.; Cheng, Shuk Han; Li, Shuisheng; Zhang, Yong; Cheng, Christopher H.K.; Lin, Haoran; College of Ocean, Hainan University, Haikou 570228, Hainan

    2013-05-24

    Highlights: •The Gper expression was detected in the developing brain of zebrafish. •Gper morpholino knockdown induced apoptosis of brain cells. •Gper morpholino knockdown reduced expression in neuron markers. •Zebrafish Gper may be involved in neuronal development. -- Abstract: G-protein-coupled estrogen receptor 1 (Gper, formerly known as GPR30) is found to be a trophic and protective factor in mediating action of estrogen in adult brain, while its role in developing brain remains to be elucidated. Here we present the expression pattern of Gper and its functions during embryogenesis in zebrafish. Both the mRNA and protein of Gper were detected throughout embryogenesis. Whole mount in situ hybridization (WISH) revealed a wide distribution of gper mRNAs in various regions of the developing brain. Gper knockdown by specific morpholinos resulted in growth retardation in embryos and morphological defects in the developing brain. In addition, induced apoptosis, decreased proliferation of the brain cells and maldevelopment of sensory and motor neurons were also found in the morphants. Our results provide novel insights into Gper functions in the developing brain, revealing that Gper can maintain the survival of the brain cells, and formation and/or differentiation of the sensory and motor neurons.

  12. Evidence of extra-telomeric effects of hTERT and its regulation involving a feedback loop

    SciTech Connect (OSTI)

    Lai, Serene R.; Cunningham, Amanda P.; Huynh, Vu Q.; Andrews, Lucy G.; Tollefsbol, Trygve O. . E-mail: trygve@uab.edu

    2007-01-15

    The human telomerase reverse transcriptase (hTERT) is the catalytic subunit of the enzyme telomerase which is responsible for telomeric maintenance and extension. Using RNA interference to knock down hTERT mRNA expression, we provide evidence that hTERT exerts extra-telomeric effects on the cell cycle and on its own regulatory proteins, specifically: p53 and p21. We tested our hypothesis that hTERT regulates its own expression through effects on upstream regulatory genes using transformed human embryonic kidney (HEK 293) cells, p53 and p16 {sup INK4a} null human ovarian cancer SKOV-3 cells, and p53-null MDA-MB-157 human mammary cancer cells. In HEK 293 cells, hTERT knockdown resulted in elevated p53 and p21 transcription and a decrease in cellular proliferation. Similar results were observed in the MDA-MB-157 cell line where p21 was upregulated, correlating with cell growth inhibition. In contrast, we observed a decrease in expression of p21 in SKOV-3 cells with hTERT knockdown and cell growth appeared to be unaffected. These findings suggest that hTERT may be involved in a feedback loop system, thereby playing a role in its own regulation.

  13. H2-M polymorphism in mice susceptible to collagen-induced arthritis involves the peptide binding groove

    SciTech Connect (OSTI)

    Walter, W.; Loos, M.; Maeurer, M.J.

    1996-12-31

    The ability to develop type II collagen (CII)-induced arthritis (CIA) in mice is associated with the major histocompatibility I-A gene and with as yet poorly defined regulatory molecules of the major histocompatibility complex (MHC) class II antigen processing and presentation pathway. H2-M molecules are thought to be involved in the loading of antigenic peptides into the MHC class II binding cleft. We sequenced H2-Ma, H2-Mb1, and H2-Mb2 genes from CIA-susceptible and -resistant mouse strains and identified four different Ma and Mb2 alleles, and three different Mb1 alleles defined by polymorphic residues within the predicted peptide binding groove. Most CIA-resistant mouse strains share common Ma, Mb1, and Mb2 alleles. In contrast, H2-M alleles designated Ma-III, Ma-IV, Mb1-III, and Mb2-IV could be exclusively identified in the CIA-susceptible H2{sup r} and H2{sup q} haplotypes, suggesting that allelic H2-M molecules may modulate the composition of different CII peptides loaded onto MHC class II molecules, presumably presenting {open_quotes}arthritogenic{close_quotes} epitopes to T lymphocytes. 42 refs., 4 figs., 3 tabs.

  14. THE MULTILINEAR ICA DECOMPOSITION WITH APPLICATIONS TO NSS MODELING Raghu G. Raj and Alan C. Bovik

    E-Print Network [OSTI]

    Texas at Austin, University of

    ], most of which involve the construction of different cost functions (usually variations or special cases and discuss applications to non-stationarity detection and natural scene statistics (NSS) modeling. Index The construction of accurate prior models of source data is essential to many applications, such as low

  15. Cognitive Science Q270, section 11246 Experiments and Models in Cognition

    E-Print Network [OSTI]

    Indiana University

    report. The project should either involve experimenting on human subjects or the formal modeling of human 11246 Experiments and Models in Cognition Fall 2009 Tu, Th 2:30-3:45, Room 228 Psychology Bldg project: 15% Lab 2 Apparent motion experiment & computational simulation: 11% Lab 3 Word perception

  16. Mathematical Analysis of a model describing the invasion of bacteria in burn wounds #

    E-Print Network [OSTI]

    Eindhoven, Technische Universiteit

    and references). The rapid development of antibiotic resistance among bacteria has added urgency to the taskMathematical Analysis of a model describing the invasion of bacteria in burn wounds # D. Hilhorst arises as a model for host tissue degradation by bacteria and involves a parameter describing

  17. Mathematical Analysis of a model describing the invasion of bacteria in burn wounds

    E-Print Network [OSTI]

    Eindhoven, Technische Universiteit

    and references). The rapid development of antibiotic resistance among bacteria has added urgency to the taskMathematical Analysis of a model describing the invasion of bacteria in burn wounds D. Hilhorst arises as a model for host tissue degradation by bacteria and involves a parameter describing

  18. A topological analysis of the magnetic breakout model for an eruptive solar flare

    E-Print Network [OSTI]

    Priest, Eric

    A topological analysis of the magnetic breakout model for an eruptive solar flare BY RHONA MACLEAN model gives an elegant explanation for the onset of an eruptive solar flare, involving magnetic types of bifurcation. Keywords: solar flare; magnetic breakout; magnetic topology; solar corona 1

  19. ``lyngby'' --a modeler's Matlab toolbox for spatiotemporal analysis of functional neuroimages

    E-Print Network [OSTI]

    Nielsen, Finn Årup

    combination of biological and engineering mechanisms involved in the acquission of functional brain images of modeling tools). To further this research we have developed a software toolbox based on the popular Matlab for removing time trends, inter­repetition offsets etc.; modeling and visualisation of brain maps (summary

  20. Modeling Silicon Photonics in Distributed Computing Systems: from the Device to the Rack

    E-Print Network [OSTI]

    Bergman, Keren

    systems involving millions of devices have to be modeled. We review key model transformation methods. Introduction Optical systems have dominated the long haul telecom market for a few decades now. Medium to long dissipation over long distances. However, as photonics expands to the datacom market and tries to get

  1. CLIMATE SCIENCE The Community Climate System Model results from a multi-agency collaboration

    E-Print Network [OSTI]

    Long, Nicholas

    . Thus, climate science--which by nature involves advanced computing technology and methods--has beenCLIMATE SCIENCE The Community Climate System Model results from a multi-agency collaboration designed to construct cutting-edge climate science simulation models for a broad research community

  2. Proceedings of the ASME 2011 Pacific Rim Technical Conference and Exhibition on Packaging and Integration of Electronic and Photonic Systems,MEMS and NEMS

    E-Print Network [OSTI]

    Lee, Hsien-Hsin "Sean"

    ], but in addition, companies face the fact that annual data center op-ex costs can exceed the cap-ex costs

  3. Pearle's Hidden-Variable Model Revisited

    E-Print Network [OSTI]

    Richard D. Gill

    2015-05-19

    Pearle (1970) gave an example of a local hidden variables model which exactly reproduced the singlet correlations of quantum theory, through the device of data-rejection: particles can fail to be detected in a way which depends on the hidden variables carried by the particles and on the measurement settings. If the experimenter computes correlations between measurement outcomes of particle pairs for which both particles are detected, he is actually looking at a subsample of particle pairs, determined by interaction involving both measurement settings and the hidden variables carried in the particles. We correct a mistake in Pearle's formulas (a normalization error) and more importantly show that the model is more simple than first appears. We illustrate with visualisations of the model and with a small simulation experiment, with code in the statistical programming language R included in the paper. Open problems are discussed.

  4. A Biomechanical Model for Dictyostelium Motility

    E-Print Network [OSTI]

    Buenemann, Mathias; Rappel, Wouter-Jan; Sander, Leonard M

    2009-01-01

    The crawling motion of Dictyostelium discoideum on substrata involves a number of coordinated events including cell contractions and cell protrusions. The mechanical forces exerted on the substratum during these contractions have recently been quantified using traction force experiments. Based on the results from these experiments, we present a biomechanical model of Dictyostelium discoideum motility with an emphasis on the adhesive properties of the cell-substratum contact. Our model assumes that the cell contracts at a constant rate and is bound to the substratum by adhesive bridges which are modeled as elastic springs. These bridges are established at a spatially uniform rate while detachment occurs at a spatially varying, load-dependent rate. Using Monte-Carlo simulations and assuming a rigid substratum, we find that the cell speed depends only weakly on the adhesive properties of the cell-substratum, in agreement with experimental data. Varying the parameters that control the adhesive and contractile pro...

  5. Modeling direct interband tunneling. I. Bulk semiconductors

    SciTech Connect (OSTI)

    Pan, Andrew; Chui, Chi On

    2014-08-07

    Interband tunneling is frequently studied using the semiclassical Kane model, despite uncertainty about its validity. Revisiting the physical basis of this formula, we find that it neglects coupling to other bands and underestimates transverse tunneling. As a result, significant errors can arise at low and high fields for small and large gap materials, respectively. We derive a simple multiband tunneling model to correct these defects analytically without arbitrary parameters. Through extensive comparison with band structure and quantum transport calculations for bulk InGaAs, InAs, and InSb, we probe the accuracy of the Kane and multiband formulas and establish the superiority of the latter. We also show that the nonlocal average electric field should be used when applying either of these models to nonuniform potentials. Our findings are important for efficient analysis and simulation of bulk semiconductor devices involving tunneling.

  6. Chemistry Old Models New Models The Mayo-Lewis Copolymerization Model

    E-Print Network [OSTI]

    Ponomarenko, Vadim

    Chemistry Old Models New Models The Mayo-Lewis Copolymerization Model Vadim Ponomarenko Department://www-rohan.sdsu.edu/vadim/mayolewis.pdf #12;Chemistry Old Models New Models Outline Chemistry Old Models New Models #12;Chemistry Old Models New Models Outline Chemistry Old Models New Models #12;Chemistry Old Models New Models Basics

  7. Surface photovoltage measurements and finite element modeling of SAW devices.

    SciTech Connect (OSTI)

    Donnelly, Christine

    2012-03-01

    Over the course of a Summer 2011 internship with the MEMS department of Sandia National Laboratories, work was completed on two major projects. The first and main project of the summer involved taking surface photovoltage measurements for silicon samples, and using these measurements to determine surface recombination velocities and minority carrier diffusion lengths of the materials. The SPV method was used to fill gaps in the knowledge of material parameters that had not been determined successfully by other characterization methods. The second project involved creating a 2D finite element model of a surface acoustic wave device. A basic form of the model with the expected impedance response curve was completed, and the model is ready to be further developed for analysis of MEMS photonic resonator devices.

  8. Identification of slow molecular order parameters for Markov model construction

    E-Print Network [OSTI]

    Perez-Hernandez, Guillermo; Giorgino, Toni; de Fabritiis, Gianni; Noé, Frank

    2013-01-01

    A goal in the kinetic characterization of a macromolecular system is the description of its slow relaxation processes, involving (i) identification of the structural changes involved in these processes, and (ii) estimation of the rates or timescales at which these slow processes occur. Most of the approaches to this task, including Markov models, Master-equation models, and kinetic network models, start by discretizing the high-dimensional state space and then characterize relaxation processes in terms of the eigenvectors and eigenvalues of a discrete transition matrix. The practical success of such an approach depends very much on the ability to finely discretize the slow order parameters. How can this task be achieved in a high-dimensional configuration space without relying on subjective guesses of the slow order parameters? In this paper, we use the variational principle of conformation dynamics to derive an optimal way of identifying the "slow subspace" of a large set of prior order parameters - either g...

  9. MODELS AND HISTORY OF MODELING Hermann Schichl

    E-Print Network [OSTI]

    Schichl, Hermann

    -Sun and Earth-Moon and, best known, the circumference of the Earth by a mathemati- cal/geometric model mechanics by circles, developed by 150 AD a mathematical model of the solar system with circlesChapter 2 MODELS AND HISTORY OF MODELING Hermann Schichl Institut f¨ur Mathematik der Universit

  10. I&C Modeling in SPAR Models

    SciTech Connect (OSTI)

    John A. Schroeder

    2012-06-01

    The Standardized Plant Analysis Risk (SPAR) models for the U.S. commercial nuclear power plants currently have very limited instrumentation and control (I&C) modeling [1]. Most of the I&C components in the operating plant SPAR models are related to the reactor protection system. This was identified as a finding during the industry peer review of SPAR models. While the Emergency Safeguard Features (ESF) actuation and control system was incorporated into the Peach Bottom Unit 2 SPAR model in a recent effort [2], various approaches to expend resources for detailed I&C modeling in other SPAR models are investigated.

  11. Yes-associated protein homolog, YAP-1, is involved in the thermotolerance and aging in the nematode Caenorhabditis elegans

    SciTech Connect (OSTI)

    Iwasa, Hiroaki [Department of Medical Biochemistry, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo 113-8519 (Japan); Maimaiti, Sainawaer [Department of Medical Biochemistry, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo 113-8519 (Japan); Department of Psychotherapy, The Fourth People's Hospital of Urumqi, Urumqi 830000 (China); Kuroyanagi, Hidehito [Laboratory of Gene Expression, Graduate School of Biomedical Science, Tokyo Medical and Dental University, Tokyo 113-8519 (Japan); Kawano, Shodai; Inami, Kazutoshi; Timalsina, Shikshya; Ikeda, Mitsunobu; Nakagawa, Kentaro [Department of Medical Biochemistry, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo 113-8519 (Japan); Hata, Yutaka, E-mail: yuhammch@tmd.ac.jp [Department of Medical Biochemistry, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo 113-8519 (Japan)

    2013-04-15

    The mammalian Hippo pathway comprises mammalian Ste20-like kinases (MST1/2) and large tumor suppressor kinases (LATS1/2). LATS1/2, which are activated by MST1/2, phosphorylate a transcriptional co-activator, yes-associated protein (YAP), and induce the recruitment of YAP by 14-3-3 to cytoplasm, so that the TEAD-dependent gene transcriptions are turned off. Although the core components of the Hippo pathway are well conserved in metazoans, it has been discussed that Caenorhabditis elegans lacks YAP ortholog, we found that F13E6.4 gene encodes a protein that shows sequence similarities to YAP in the N-terminal TEAD-binding domain and in the WW domain. We designated this gene as yap-1. YAP-1 is widely expressed in various cells such as epithelial cells, muscles, hypodermal cells, gonadal sheath cells, spermatheca, and hypodermal cells. YAP-1 is distributed in cytoplasm and nuclei. wts-1 (LATS ortholog) and ftt-2 (14-3-3 ortholog) knockdowns cause nuclear accumulation of YAP-1, supporting that the subcellular localization of YAP-1 is regulated in a similar way as that of YAP. Heat shock also causes the nuclear accumulation of YAP-1 but after heat shock, YAP-1 translocates to cytoplasm. Knockdowns of DAF-21 (HSP90 ortholog) and HSF-1block the nuclear export of YAP-1 during this recovery. YAP-1 overexpression is beneficial for thermotolerance, whereas YAP-1 hyperactivity induced by wts-1 and ftt-2 knockdowns is deleterious on thermal response and yap-1 deficiency promotes health aging. In short, YAP-1 partially shares basal characters with mammalian YAP and plays a role in thermal stress response and healthy aging. - Highlights: ? We named Caenorhabditis elegans F13E6.4 gene yap-1 as a putative YAP homolog. ? The localization of YAP-1 is regulated by WTS-1 and FTT-2. ? YAP-1 is involved in healthy aging and thermosensitivity.

  12. Hierarchical Dynamic Models

    E-Print Network [OSTI]

    Penny, Will

    Hierarchical Dynamic Models Will Penny OU Processes Embedding OU(2) process Dynamic Models Hierarchical Dynamic Models Will Penny 26th May 2011 #12;Hierarchical Dynamic Models Will Penny OU Processes Dynamic Models Will Penny OU Processes Embedding OU(2) process Dynamic Models Generalised coordinates

  13. Using Van Manen's model to assess levels of reflectivity among preservice physical education teachers 

    E-Print Network [OSTI]

    Ballard, Kristy Kay

    2006-10-30

    of the lesson, what should be changed, and was the content covered important to the students? Zeichner and Liston (1987) also identified four levels of reflective thought in their model. The first level is factual, where the teacher focuses on facts... are introduced to and involved in activities such as dialogue journals, developing a philosophy of education, and ?thinking outside the box.? In the second stage, students are involved in developing lesson plans for particular content areas. After...

  14. Development of Reference Models and Design Tools (LCOE Models...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Development of Reference Models and Design Tools (LCOE Models) Development of Reference Models and Design Tools (LCOE Models) Development of Reference Models and Design Tools (LCOE...

  15. Combustion instability modeling and analysis

    SciTech Connect (OSTI)

    Santoro, R.J.; Yang, V.; Santavicca, D.A.; Sheppard, E.J.

    1995-12-31

    It is well known that the two key elements for achieving low emissions and high performance in a gas turbine combustor are to simultaneously establish (1) a lean combustion zone for maintaining low NO{sub x} emissions and (2) rapid mixing for good ignition and flame stability. However, these requirements, when coupled with the short combustor lengths used to limit the residence time for NO formation typical of advanced gas turbine combustors, can lead to problems regarding unburned hydrocarbons (UHC) and carbon monoxide (CO) emissions, as well as the occurrence of combustion instabilities. The concurrent development of suitable analytical and numerical models that are validated with experimental studies is important for achieving this objective. A major benefit of the present research will be to provide for the first time an experimentally verified model of emissions and performance of gas turbine combustors. The present study represents a coordinated effort between industry, government and academia to investigate gas turbine combustion dynamics. Specific study areas include development of advanced diagnostics, definition of controlling phenomena, advancement of analytical and numerical modeling capabilities, and assessment of the current status of our ability to apply these tools to practical gas turbine combustors. The present work involves four tasks which address, respectively, (1) the development of a fiber-optic probe for fuel-air ratio measurements, (2) the study of combustion instability using laser-based diagnostics in a high pressure, high temperature flow reactor, (3) the development of analytical and numerical modeling capabilities for describing combustion instability which will be validated against experimental data, and (4) the preparation of a literature survey and establishment of a data base on practical experience with combustion instability.

  16. Disease Prediction Models and Operational Readiness

    SciTech Connect (OSTI)

    Corley, Courtney D.; Pullum, Laura L.; Hartley, David M.; Benedum, Corey M.; Noonan, Christine F.; Rabinowitz, Peter M.; Lancaster, Mary J.

    2014-03-19

    INTRODUCTION: The objective of this manuscript is to present a systematic review of biosurveillance models that operate on select agents and can forecast the occurrence of a disease event. One of the primary goals of this research was to characterize the viability of biosurveillance models to provide operationally relevant information for decision makers to identify areas for future research. Two critical characteristics differentiate this work from other infectious disease modeling reviews. First, we reviewed models that attempted to predict the disease event, not merely its transmission dynamics. Second, we considered models involving pathogens of concern as determined by the US National Select Agent Registry (as of June 2011). Methods: We searched dozens of commercial and government databases and harvested Google search results for eligible models utilizing terms and phrases provided by public health analysts relating to biosurveillance, remote sensing, risk assessments, spatial epidemiology, and ecological niche-modeling, The publication date of search results returned are bound by the dates of coverage of each database and the date in which the search was performed, however all searching was completed by December 31, 2010. This returned 13,767 webpages and 12,152 citations. After de-duplication and removal of extraneous material, a core collection of 6,503 items was established and these publications along with their abstracts are presented in a semantic wiki at http://BioCat.pnnl.gov. Next, PNNL’s IN-SPIRE visual analytics software was used to cross-correlate these publications with the definition for a biosurveillance model resulting in the selection of 54 documents that matched the criteria resulting Ten of these documents, However, dealt purely with disease spread models, inactivation of bacteria, or the modeling of human immune system responses to pathogens rather than predicting disease events. As a result, we systematically reviewed 44 papers and the results are presented in this analysis.

  17. Model reduction of systems with localized nonlinearities.

    SciTech Connect (OSTI)

    Segalman, Daniel Joseph

    2006-03-01

    An LDRD funded approach to development of reduced order models for systems with local nonlinearities is presented. This method is particularly useful for problems of structural dynamics, but has potential application in other fields. The key elements of this approach are (1) employment of eigen modes of a reference linear system, (2) incorporation of basis functions with an appropriate discontinuity at the location of the nonlinearity. Galerkin solution using the above combination of basis functions appears to capture the dynamics of the system with a small basis set. For problems involving small amplitude dynamics, the addition of discontinuous (joint) modes appears to capture the nonlinear mechanics correctly while preserving the modal form of the predictions. For problems involving large amplitude dynamics of realistic joint models (macro-slip), the use of appropriate joint modes along with sufficient basis eigen modes to capture the frequencies of the system greatly enhances convergence, though the modal nature the result is lost. Also observed is that when joint modes are used in conjunction with a small number of elastic eigen modes in problems of macro-slip of realistic joint models, the resulting predictions are very similar to those of the full solution when seen through a low pass filter. This has significance both in terms of greatly reducing the number of degrees of freedom of the problem and in terms of facilitating the use of much larger time steps.

  18. An extracytoplasmic function sigma factor-dependent periplasmic glutathione peroxidase is involved in oxidative stress response of Shewanella oneidensis

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Dai, Jingcheng; Wei, Hehong; Tian, Chunyuan; Damron, Fredrick; Zhou, Jizhong; Qiu, Dongru

    2015-01-01

    Background: Bacteria use alternative sigma factors (?s) to regulate condition-specific gene expression for survival and Shewanella harbors multiple ECF (extracytoplasmic function) ? genes and cognate anti-sigma factor genes. Here we comparatively analyzed two of the rpoE-like operons in the strain MR-1: rpoE-rseA-rseB-rseC and rpoE2-chrR. Results: RpoE was important for bacterial growth at low and high temperatures, in the minimal medium, and high salinity. The degP/htrA orthologue, required for growth of Escherichia coli and Pseudomonas aeruginosa at high temperature, is absent in Shewanella, while the degQ gene is RpoE-regulated and is required for bacterial growth at high temperature. RpoE2 was essentialmore »for the optimal growth in oxidative stress conditions because the rpoE2 mutant was sensitive to hydrogen peroxide and paraquat. The operon encoding a ferrochelatase paralogue (HemH2) and a periplasmic glutathione peroxidase (PgpD) was identified as RpoE2-dependent. PgpD exhibited higher activities and played a more important role in the oxidative stress responses than the cytoplasmic glutathione peroxidase CgpD under tested conditions. The rpoE2-chrR operon and the identified regulon genes, including pgpD and hemH2, are coincidently absent in several psychrophilic and/or deep-sea Shewanella strains. Conclusion: In S. oneidensis MR-1, the RpoE-dependent degQ gene is required for optimal growth under high temperature. The rpoE2 and RpoE2-dependent pgpD gene encoding a periplasmic glutathione peroxidase are involved in oxidative stress responses. But rpoE2 is not required for bacterial growth at low temperature and it even affected bacterial growth under salt stress, indicating that there is a tradeoff between the salt resistance and RpoE2-mediated oxidative stress responses.« less

  19. Continuous lumping model for simulation of hydrocracking

    SciTech Connect (OSTI)

    Laxminarasimhan, C.S.; Verma, R.P. [Indian Oil Corp., Faridabad (India). R and D Centre] [Indian Oil Corp., Faridabad (India). R and D Centre; Ramachandran, P.A. [Washington Univ., St. Louis, MO (United States). Dept. of Chemical Engineering] [Washington Univ., St. Louis, MO (United States). Dept. of Chemical Engineering

    1996-09-01

    Hydrocracking of vacuum gas oil is an important chemical process involving complex reaction mixtures. The reaction is carried out in a trickle-bed reactor, considering reaction kinetics along with such hydrodynamic effects as mass transfer, intraparticle diffusion, and partial wetting. Since reaction kinetics is critical to modeling and simulation of a hydrocracking reactor, a modeling approach needs to capture the complex chemistry of the process, along with the elegance of the solution method. The complex chemistry of hydrocarbon is represented by an elegant continuous lumping approach to modeling. The true boiling point of the mixture is used as the characterization parameter. Since the rate constant of hydrocracking is assumed to be a monotonic function of the true boiling point, it is possible to reformulate mass-balance equations in terms of rate constant as a continuous variable. A novel distribution function p(k,K), which determines the fractional yield distribution of species, was formulated based on data from the cracking patterns of various model compounds. Resulting integrodifferential equations are solved numerically to obtain yields of various fractions as a function of reactor residence time. Model predictions are compared with limited published data to show the utility of the model.

  20. Notes on Mayer Expansions and Matrix Models

    E-Print Network [OSTI]

    Jean-Emile Bourgine

    2014-02-03

    Mayer cluster expansion is an important tool in statistical physics to evaluate grand canonical partition functions. It has recently been applied to the Nekrasov instanton partition function of $\\mathcal{N}=2$ 4d gauge theories. The associated canonical model involves coupled integrations that take the form of a generalized matrix model. It can be studied with the standard techniques of matrix models, in particular collective field theory and loop equations. In the first part of these notes, we explain how the results of collective field theory can be derived from the cluster expansion. The equalities between free energies at first orders is explained by the discrete Laplace transform relating canonical and grand canonical models. In a second part, we study the canonical loop equations and associate them to similar relations on the grand canonical side. It leads to relate the multi-point densities, fundamental objects of the matrix model, to the generating functions of multi-rooted clusters. Finally, a method is proposed to derive loop equations directly on the grand canonical model.

  1. E6 inspired composite Higgs model

    E-Print Network [OSTI]

    Nevzorov, R

    2015-01-01

    We consider a composite Higgs model embedded into a Grand Unified Theory(GUT) based on the E_6 gauge group. The phenomenological viability of this E_6 inspired composite Higgs model (E6CHM) implies that standard model (SM) elementary fermions with different baryon or lepton number should stem from different 27 representations of E_6. We present a six-dimensional orbifold GUT model in which the E_6 gauge symmetry is broken to the SM gauge group so that the appropriate splitting of the bulk 27-plets takes place. In this model the strongly coupled sector is localised on one of the branes and possesses an SU(6) global symmetry that contains the SU(3)_C\\times SU(2)_W\\times U(1)_Y subgroup. In this case the approximate gauge coupling unification can be attained if the right-handed top quark is a composite state and the elementary sector involves extra exotic matter beyond the SM which ensures anomaly cancellation. The breakdown of the approximate SU(6) symmetry at low energies in this model results in a set of the ...

  2. Topological Massive Sigma Models

    E-Print Network [OSTI]

    N. D. Lambert

    1995-05-03

    In this paper we construct topological sigma models which include a potential and are related to twisted massive supersymmetric sigma models. Contrary to a previous construction these models have no central charge and do not require the manifold to admit a Killing vector. We use the topological massive sigma model constructed here to simplify the calculation of the observables. Lastly it is noted that this model can be viewed as interpolating between topological massless sigma models and topological Landau-Ginzburg models.

  3. Nano-Continuum Modeling of a Nuclear Glass Specimen Altered for 25 Years

    SciTech Connect (OSTI)

    Steefel, Carl

    2014-01-06

    The purpose of this contribution is to report on preliminary nano-continuum scale modeling of nuclear waste glass corrosion. The focus of the modeling is an experiment involving a French glass SON68 specimen leached for 25 years in a granitic environment. In this report, we focus on capturing the nano-scale concentration profiles. We use a high resolution continuum model with a constant grid spacing of 1 nanometer to investigate the glass corrosion mechanisms.

  4. Conventional regression models Unlabelled units

    E-Print Network [OSTI]

    McCullagh, Peter

    Conventional regression models Unlabelled units Consequences Sampling bias in logistic models Peter effects #12;Conventional regression models Unlabelled units Consequences Outline 1 Conventional regression models Gaussian models Binary regression model Properties of conventional models 2 Unlabelled units Point

  5. Model solution State variable model: differential equation

    E-Print Network [OSTI]

    Limburg, Karin E.

    2/26/2014 1 Model solution State variable model: differential equation Models a rate of change equation General solution: the antiderivative Particular solution: require initial and boundary conditions up the general solution to a differential equation in a book Solve for initial and boundary

  6. Bringing Alaska North Slope Natural Gas to Market (released in AEO2009)

    Reports and Publications (EIA)

    2009-01-01

    At least three alternatives have been proposed over the years for bringing sizable volumes of natural gas from Alaska's remote North Slope to market in the lower 48 states: a pipeline interconnecting with the existing pipeline system in central Alberta, Canada; a gas-to-liquids (GTL) plant on the North Slope; and a large liquefied natural gas (LNG) export facility at Valdez, Alaska. The National Energy Modeling System (NEMS) explicitly models the pipeline and GTL options. The what if LNG option is not modeled in NEMS.

  7. Model-independent approaches for the XFEM in fracture Safdar Abbas1 Alaskar Alizada2 and Thomas-Peter Fries2

    E-Print Network [OSTI]

    Model-independent approaches for the XFEM in fracture mechanics Safdar Abbas1 Alaskar Alizada2 to fracture mechanics involve enriching the regions near the crack-tips. The accuracy of such approximations fields in the near-tip region for the fracture model considered. Consequently, for each fracture model

  8. A Relativistic Dynamical Collapse Model

    E-Print Network [OSTI]

    Philip Pearle

    2014-12-21

    A model is discussed where all operators are constructed from a quantum scalar field whose energy spectrum takes on all real values. The Schr\\"odinger picture wave function depends upon space and time coordinates for each particle, as well as an inexorably increasing evolution parameter $s$ which labels a foliation of space-like hypersurfaces. The model is constructed to be manifestly Lorentz invariant in the interaction picture. Free particle states and interactions are discussed in this framework. Then, the formalism of the CSL (Continuous Spontaneous Localization) theory of dynamical collapse is applied. The collapse-generating operator is chosen to to be the particle number space-time density. Unlike previous relativistically invariant models, the vacuum state is not excited. The collapse dynamics depends upon two parameters, a parameter $\\Lambda$ which represents the collapse rate/volume and a scale factor $\\ell$. A common example of collapse dynamics, involving a clump of matter in a superposition of two locations, is analyzed. The collapse rate is shown to be identical to that of non-relativistic CSL when the GRW-CSL choice of $\\ell=a=10^{-5}$cm, is made, along with $\\Lambda=\\lambda/a^{3}$ (GRW-CSL choice $\\lambda=10^{-16}s^{-1}$). However, it is also shown that the change of mass of a nucleon over the age of the universe is then unacceptably large. The case where $\\ell$ is the size of the universe is then considered. It is shown that the collapse behavior is satisfactory and the change of mass over the age of the universe is acceptably small, when $\\Lambda= \\lambda/\\ell a^{2}$.

  9. Sandia Modeling Tool Webinar

    Office of Energy Efficiency and Renewable Energy (EERE)

    Webinar attendees will learn what collaborative, stakeholder-driven modeling is, how the models developed have been and could be used, and how specifically this process and resulting models might...

  10. Sandia Energy - Theory & Modeling

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Theory & Modeling Home Transportation Energy Predictive Simulation of Engines Combustion Chemistry Theory & Modeling Theory & ModelingAshley Otero2015-10-28T02:44:07+00:00 The CRF...

  11. Nonlinear models Nonlinear Regression

    E-Print Network [OSTI]

    Penny, Will

    Nonlinear models Will Penny Nonlinear Regression Nonlinear Regression Priors Energies Posterior Metropolis-Hasting Proposal density References Nonlinear models Will Penny Bayesian Inference Course, WTCN, UCL, March 2013 #12;Nonlinear models Will Penny Nonlinear Regression Nonlinear Regression Priors

  12. Runtime Tracing of The Community Earth System Model: Feasibility and Benefits

    SciTech Connect (OSTI)

    Wang, Dali [ORNL] [ORNL; Domke, Jens [ORNL] [ORNL

    2011-01-01

    Community Earth System Models (CESM) is one of US's leading earth system modeling systems, which has over decades of development history and embraced by large, active user communities. In this paper, we first review the history of CESM software development and layout the general objectives of performance analysis. Then we present an offline global community land model simulation within the CESM framework to demonstrate the procedure of runtime tracing of CESM using the Vampir toolset. Finally, we explain the benefits of runtime tracing to the general earth system modeling community. We hope those considerations can also be beneficial to many other modeling research programs involving legacy high-performance computing applications.

  13. Buried pipelines essentially involve problems of soil-structure interaction that include several complex factors such as geometry, material properties, and boundary

    E-Print Network [OSTI]

    Al-Shayea, Naser Abdul-Rahman

    1 Abstract Buried pipelines essentially involve problems of soil-structure interaction that include Bend, and Buckling Check. Keywords: buried pipelines, regression, horizontal bend, vertical bend, homoscedasticity, normality. 1 Introduction Analysis and design of buried pipelines are usually based on classical

  14. Rea1, a Dynein-related Nuclear AAA-ATPase, Is Involved in Late rRNA Processing and Nuclear Export of 60 S Subunits*S

    E-Print Network [OSTI]

    Nissan, Tracy

    Rea1, a Dynein-related Nuclear AAA-ATPase, Is Involved in Late rRNA Processing and Nuclear Export we report that Rea1 is required for maturation and nuclear export of the pre-60 S subunit. Rea1. Using an in vivo 60 S subunit export assay, a strong accumulation of the large subunit reporter Rpl25

  15. In an international collaboration, Drs Thomas Roscoe and Ljerka Kunst are developing powerful genetic approaches to identify the mechanisms involved in regulating oil production in seeds. Their

    E-Print Network [OSTI]

    genetic approaches to identify the mechanisms involved in regulating oil production in seeds in the regulation of seed oil production in the embryo by the French team; third, the discovery of new information. Their exciting work will lead to the development of new crops for biofuel production As joint project

  16. LIGHT is involved in the pathogenesis of rheumatoid arthritis by inducing the expression of pro-inflammatory cytokines and MMP-9

    E-Print Network [OSTI]

    Lee, Won-Ha

    LIGHT is involved in the pathogenesis of rheumatoid arthritis by inducing the expression of pro inflammation and cartilage destruction.7­9 LIGHT (TNFSF14) is a member of tumor necrosis factor superfamily and is the ligand for TR2 (TNFRSF14/HVEM/ HveA/LIGHTR/ATAR) and lymphotoxin (LT)-b.10­12 LIGHT is known

  17. In Vitro Drug Sensitivity-Gene Expression Correlations Involve a Tissue of Origin C. R. Andersson, M. Fryknas, L. Rickardson, R. Larsson, A. Isaksson, and

    E-Print Network [OSTI]

    In Vitro Drug Sensitivity-Gene Expression Correlations Involve a Tissue of Origin Dependency C. R concern of chemogenomics is to associate drug activity with biological variables. Several reports have clustered cell line drug activity profiles as well as drug activity-gene expression correlation profiles

  18. How Reliable are Parallel Disk Systems When Energy-Saving Schemes are Involved? Shu Yin, Xiaojun Ruan, Adam Manzanares, and Xiao Qin

    E-Print Network [OSTI]

    Qin, Xiao

    How Reliable are Parallel Disk Systems When Energy-Saving Schemes are Involved? Shu Yin, Xiaojun, growing evidence shows that energy-saving schemes in disk drives usually have negative impacts on storage - called MINT - to evaluate the reliability of a parallel disk system where energy-saving mechanisms

  19. Value of Citizen Science Monitoring Involving citizen scientists in the sea star wasting disease survey effort will greatly expand our spatial

    E-Print Network [OSTI]

    California at Santa Cruz, University of

    Value of Citizen Science Monitoring Involving citizen scientists in the sea star wasting disease survey effort will greatly expand our spatial and temporal coverage. Citizen science groups can collect. A researcher from the MARINe group should accompany each citizen science group in the field to assist

  20. Automatically Creating Design Models from 3D Anthropometry Data

    E-Print Network [OSTI]

    Wuhrer, Stefanie; Bose, Prosenjit

    2011-01-01

    When designing a product that needs to fit the human shape, designers often use a small set of 3D models, called design models, either in physical or digital form, as representative shapes to cover the shape variabilities of the population for which the products are designed. Until recently, the process of creating these models has been an art involving manual interaction and empirical guesswork. The availability of the 3D anthropometric databases provides an opportunity to create design models optimally. In this paper, we propose a novel way to use 3D anthropometric databases to generate design models that represent a given population for design applications such as the sizing of garments and gear. We generate the representative shapes by solving a covering problem in a parameter space. Well-known techniques in computational geometry are used to solve this problem. We demonstrate the method using examples in designing glasses and helmets.

  1. Multiscale modeling of solar cells with interface phenomena

    E-Print Network [OSTI]

    Foster, David H; Peszynska, Malgorzata; Schneider, Guenter

    2013-01-01

    We describe a mathematical model for heterojunctions in semiconductors which can be used, e.g., for modeling higher efficiency solar cells. The continuum model involves well-known drift-diffusion equations posed away from the interface. These are coupled with interface conditions with a nonhomogeneous jump for the potential, and Robin-like interface conditions for carrier transport. The interface conditions arise from approximating the interface region by a lower-dimensional manifold. The data for the interface conditions are calculated by a Density Functional Theory (DFT) model over a few atomic layers comprising the interface region. We propose a domain decomposition method (DDM) approach to decouple the continuum model on subdomains which is implemented in every step of the Gummel iteration. We show results for CIGS/CdS, Si/ZnS, and Si/GaAs heterojunctions.

  2. Relativistic nuclear matter with alternative derivative coupling models

    SciTech Connect (OSTI)

    Delfino, A.; Coelho, C.T.; Malheiro, M. (Instituto de Fisica-Universidade Federal Fluminense, Outeiro de Sao Joao Batista s/n, 24020-004 Centro, Niteroi, Rio de Janeiro (Brazil))

    1995-04-01

    Effective Lagrangians involving nucleons coupled to scalar and vector fields are investigated within the framework of relativistic mean-field theory. The study presents the traditional Walecka model and different kinds of scalar derivative couplings suggested by Zimanyi and Moszkowski. The incompressibility (presented in an analytical form), scalar potential, and vector potential at the saturation point of nuclear matter are compared for these models. The real optical potential for the models are calculated and one of the models fits well the experimental curve from [minus]50 to 400 MeV while also giving a soft equation of state. By varying the coupling constants and keeping the saturation point of nuclear matter approximately fixed, only the Walecka model presents a first order phase transition for finite temperature at zero density.

  3. Progress in D-brane model building

    E-Print Network [OSTI]

    Fernando Marchesano

    2007-03-05

    The state of the art in D-brane model building is briefly reviewed, focusing on recent achievements in the construction of D=4 N = 1 type II string vacua with semi-realistic gauge sectors. Such progress relies on a better understanding of the spectrum of BPS D-branes, the effective field theory obtained from them and the explicit construction of vacua. We first consider D-branes in standard Calabi-Yau compactifications, and then the more involved case of compactifications with fluxes. We discuss how the non-trivial interplay between D-branes and fluxes modifies the previous model-building rules, as well as provides new possibilities to connect string theory to particle physics.

  4. CAMPUS ENERGY MODEL

    Energy Science and Technology Software Center (OSTI)

    003655IBMPC00 Campus Energy Model for Control and Performance Validation  https://github.com/NREL/CampusEnergyModeling/releases/tag/v0.2.1 

  5. Modeling and Analysis

    Broader source: Energy.gov [DOE]

    DOE modeling and analysis activities focus on reducing uncertainties and improving transparency in photovoltaics (PV) and concentrating solar power (CSP) performance modeling. The overall goal of...

  6. Development of long-term performance models for radioactive waste forms

    SciTech Connect (OSTI)

    Bacon, Diana H.; Pierce, Eric M.

    2011-03-22

    The long-term performance of solid radioactive waste is measured by the release rate of radionuclides into the environment, which depends on corrosion or weathering rates of the solid waste form. The reactions involved depend on the characteristics of the solid matrix containing the radioactive waste, the radionuclides of interest, and their interaction with surrounding geologic materials. This chapter describes thermo-hydro-mechanical and reactive transport models related to the long-term performance of solid radioactive waste forms, including metal, ceramic, glass, steam reformer and cement. Future trends involving Monte-Carlo simulations and coupled/multi-scale process modeling are also discussed.

  7. A View on Future Building System Modeling and Simulation

    SciTech Connect (OSTI)

    Wetter, Michael

    2011-04-01

    This chapter presents what a future environment for building system modeling and simulation may look like. As buildings continue to require increased performance and better comfort, their energy and control systems are becoming more integrated and complex. We therefore focus in this chapter on the modeling, simulation and analysis of building energy and control systems. Such systems can be classified as heterogeneous systems because they involve multiple domains, such as thermodynamics, fluid dynamics, heat and mass transfer, electrical systems, control systems and communication systems. Also, they typically involve multiple temporal and spatial scales, and their evolution can be described by coupled differential equations, discrete equations and events. Modeling and simulating such systems requires a higher level of abstraction and modularisation to manage the increased complexity compared to what is used in today's building simulation programs. Therefore, the trend towards more integrated building systems is likely to be a driving force for changing the status quo of today's building simulation programs. Thischapter discusses evolving modeling requirements and outlines a path toward a future environment for modeling and simulation of heterogeneous building systems.A range of topics that would require many additional pages of discussion has been omitted. Examples include computational fluid dynamics for air and particle flow in and around buildings, people movement, daylight simulation, uncertainty propagation and optimisation methods for building design and controls. For different discussions and perspectives on the future of building modeling and simulation, we refer to Sahlin (2000), Augenbroe (2001) and Malkawi and Augenbroe (2004).

  8. Int. J. Environment and Pollution, Vol. 54, No. 1, 2014 17 Spline interpolation for modelling of accumulated

    E-Print Network [OSTI]

    Dimov, Ivan

    consideration is of great importance when modelling results, obtained after running large-scale air pollution his PhD in 2007 with thesis about the numerical simulation of the transboundary air pollution over SE, numerical modelling, air pollution and planetary boundary layer dynamics. He has been involved

  9. A simple model for amplified spontaneous emission in dyes

    SciTech Connect (OSTI)

    Garrison, J.C.; Hong, Chung Ki; Nathel, H.

    1990-01-09

    Amplified spontaneous emission in dyes is modelled by replacing the actual molecular spectrum by an effective four-level atom which includes the levels involved in pumping and stimulated emission. Propagation of the signal and pump waves is described in the slowly varying envelope approximation. It is shown that the saturation intensity of the signal depends on the pump intensity, and reciprocally that the pump saturation intensity depends on the signal intensity. 1 fig.

  10. Collaborative Research: Towards Advanced Understanding and Predictive Capability of Climate Change in the Arctic Using a High-Resolution Regional Arctic Climate Model

    SciTech Connect (OSTI)

    Cassano, John

    2013-06-30

    The primary research task completed for this project was the development of the Regional Arctic Climate Model (RACM). This involved coupling existing atmosphere, ocean, sea ice, and land models using the National Center for Atmospheric Research (NCAR) Community Climate System Model (CCSM) coupler (CPL7). RACM is based on the Weather Research and Forecasting (WRF) atmospheric model, the Parallel Ocean Program (POP) ocean model, the CICE sea ice model, and the Variable Infiltration Capacity (VIC) land model. A secondary research task for this project was testing and evaluation of WRF for climate-scale simulations on the large pan-Arctic model domain used in RACM. This involved identification of a preferred set of model physical parameterizations for use in our coupled RACM simulations and documenting any atmospheric biases present in RACM.

  11. Studies involving high temperature desulfurization/regeneration reactions of metal oxides for fuel cell development. Final report

    SciTech Connect (OSTI)

    Jalan, V.

    1983-10-01

    Research conducted at Giner, Inc. during 1981 to 1983 under the present contract has been a continuation of the investigation of a high temperature regenerable desulfurization process capable of reducing the sulfur content in coal gases from 200 ppM to 1 ppM. The overall objective has been the integration of a coal gasifier with a molten carbonate fuel cell, which requires that the sulfur content be below 1 ppM. Commercially available low temperature processes incur an excessive energy penalty. Results obtained with packed-bed and fluidized bed reactors have demonstrated that a CuO/ZnO mixed oxide sorbent is regenerable and capable of lowering the sulfur content (as H/sub 2/S and COS) from 200 ppM in simulated hot coal-derived gases to below 1 ppM level at 600 to 650/sup 0/C. Four potential sorbents (copper, tungsten oxide, vanadium oxide and zinc oxide) were initially selected for experimental use in hot regenerable desulfurization in the temperature range 500 to 650/sup 0/C. Based on engineering considerations, such as desulfurization capacity in per weight or volume of sorbents, a coprecipitated CuO/ZnO was selected for further study. A structural reorganization mechanism, unique to mixed oxides, was identified: the creation of relatively fine crystallites of the sulfided components (Cu/sub 2/S and ZnS) to counteract the loss of surface area due to sintering during regeneration. Studies with 9 to 26% water vapor in simulated coal gases show that sulfur levels below 1 ppM can be achieved in the temperature range of 500/sup 0/ to 650/sup 0/C. The ability of CuO/ZnO to remove COS, CS/sub 2/ and CH/sub 3/SH at these conditions has been demonstrated in this study. Also a previously proposed pore-plugging model was further developed with good success for data treatment of both packed bed and fluidized-bed reactors. 96 references, 42 figures, 21 tables.

  12. Biomass Scenario Model

    SciTech Connect (OSTI)

    2015-09-01

    The Biomass Scenario Model (BSM) is a unique, carefully validated, state-of-the-art dynamic model of the domestic biofuels supply chain which explicitly focuses on policy issues, their feasibility, and potential side effects. It integrates resource availability, physical/technological/economic constraints, behavior, and policy. The model uses a system dynamics simulation (not optimization) to model dynamic interactions across the supply chain.

  13. Next Generation Calibration Models with Dimensional Modeling...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Decision Tree Based Control Model-Based Transient Calibration Optimization for Next Generation Diesel Engines An Accelerated Aging Method for Diesel Exhaust Aftertreatment Systems...

  14. Dynamic cable analysis models

    SciTech Connect (OSTI)

    Palo, P.A.; Meggitt, D.J.; Nordell, W.J.

    1983-05-01

    This paper presents a summary of the development and validation of undersea cable dynamics computer models by the Naval Civil Engineering Laboratory (NCEL) under the sponsorship of the Naval Facilities Engineering Command. These models allow for the analysis of both small displacement (strumming) and large displacement (static and dynamic) deformations of arbitrarily configured cable structures. All of the large displacement models described in this paper are available to the public. This paper does not emphasize the theoretical development of the models (this information is available in other references) but emphasizes the various features of the models, the comparisons between model output and experimental data, and applications for which the models have been used.

  15. Innovative mathematical modeling in environmental remediation

    SciTech Connect (OSTI)

    Yeh, Gour T. [Taiwan Typhoon and Flood Research Institute (Taiwan); National Central Univ. (Taiwan); Univ. of Central Florida (United States); Gwo, Jin Ping [Nuclear Regulatory Commission (NRC), Rockville, MD (United States); Siegel, Malcolm D. [Sandia National Laboratories, Albuquerque, NM (United States); Li, Ming-Hsu [National Central Univ. (Taiwan); ; Fang, Yilin [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Zhang, Fan [Inst. of Tibetan Plateau Research, Chinese Academy of Sciences (China); Luo, Wensui [Inst. of Tibetan Plateau Research, Chinese Academy of Sciences (China); Yabusaki, Steven B. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)

    2013-05-01

    There are two different ways to model reactive transport: ad hoc and innovative reaction-based approaches. The former, such as the Kd simplification of adsorption, has been widely employed by practitioners, while the latter has been mainly used in scientific communities for elucidating mechanisms of biogeochemical transport processes. It is believed that innovative mechanistic-based models could serve as protocols for environmental remediation as well. This paper reviews the development of a mechanistically coupled fluid flow, thermal transport, hydrologic transport, and reactive biogeochemical model and example-applications to environmental remediation problems. Theoretical bases are sufficiently described. Four example problems previously carried out are used to demonstrate how numerical experimentation can be used to evaluate the feasibility of different remediation approaches. The first one involved the application of a 56-species uranium tailing problem to the Melton Branch Subwatershed at Oak Ridge National Laboratory (ORNL) using the parallel version of the model. Simulations were made to demonstrate the potential mobilization of uranium and other chelating agents in the proposed waste disposal site. The second problem simulated laboratory-scale system to investigate the role of natural attenuation in potential off-site migration of uranium from uranium mill tailings after restoration. It showed inadequacy of using a single Kd even for a homogeneous medium. The third example simulated laboratory experiments involving extremely high concentrations of uranium, technetium, aluminum, nitrate, and toxic metals (e.g.,Ni, Cr, Co).The fourth example modeled microbially-mediated immobilization of uranium in an unconfined aquifer using acetate amendment in a field-scale experiment. The purposes of these modeling studies were to simulate various mechanisms of mobilization and immobilization of radioactive wastes and to illustrate how to apply reactive transport models for environmental remediation.The second problem simulated laboratory-scale system to investigate the role of natural attenuation in potential off-site migration of uranium from uranium mill tailings after restoration. It showed inadequacy of using a single Kd even for a homogeneous medium.

  16. Model development for household waste prevention behaviour

    SciTech Connect (OSTI)

    Bortoleto, Ana Paula; Kurisu, Kiyo H.; Hanaki, Keisuke

    2012-12-15

    Highlights: Black-Right-Pointing-Pointer We model waste prevention behaviour using structure equation modelling. Black-Right-Pointing-Pointer We merge attitude-behaviour theories with wider models from environmental psychology. Black-Right-Pointing-Pointer Personal norms and perceived behaviour control are the main behaviour predictors. Black-Right-Pointing-Pointer Environmental concern, moral obligation and inconvenience are the main influence on the behaviour. Black-Right-Pointing-Pointer Waste prevention and recycling are different dimensions of waste management behaviour. - Abstract: Understanding waste prevention behaviour (WPB) could enable local governments and decision makers to design more-effective policies for reducing the amount of waste that is generated. By merging well-known attitude-behaviour theories with elements from wider models from environmental psychology, an extensive cognitive framework that provides new and valuable insights is developed for understanding the involvement of individuals in waste prevention. The results confirm the usefulness of the theory of planned behaviour and of Schwartz's altruistic behaviour model as bases for modelling participation in waste prevention. A more elaborate integrated model of prevention was shown to be necessary for the complete analysis of attitudinal aspects associated with waste prevention. A postal survey of 158 respondents provided empirical support for eight of 12 hypotheses. The proposed structural equation indicates that personal norms and perceived behaviour control are the main predictors and that, unlike the case of recycling, subjective norms have a weak influence on WPB. It also suggests that, since social norms have not presented a direct influence, WPB is likely to be influenced by a concern for the environment and the community as well by perceptions of moral obligation and inconvenience. Results also proved that recycling and waste prevention represent different dimensions of waste management behaviour requiring particular approaches to increase individuals' engagement in future policies.

  17. Sensitivity analysis of the fission gas behavior model in BISON.

    SciTech Connect (OSTI)

    Swiler, Laura Painton; Pastore, Giovanni; Perez, Danielle; Williamson, Richard

    2013-05-01

    This report summarizes the result of a NEAMS project focused on sensitivity analysis of a new model for the fission gas behavior (release and swelling) in the BISON fuel performance code of Idaho National Laboratory. Using the new model in BISON, the sensitivity of the calculated fission gas release and swelling to the involved parameters and the associated uncertainties is investigated. The study results in a quantitative assessment of the role of intrinsic uncertainties in the analysis of fission gas behavior in nuclear fuel.

  18. Reducing Model Systematic Error through Super Modelling

    E-Print Network [OSTI]

    Selten, Frank

    al., 2011 #12;Structure of Super Model COSMOS model (MPI, Germany) AGCM: ECHAM5, T31L19 (~3.75 degrees horizontally) OGCM: MPIOM, GR30L40 (~3 degrees) #12;Correlation of Wind Stress Ocean Atmosphere Performance Index (PI): Reichler & Kim, 2008, BAMS (1 )Nordeng TiedtkeQ Q Q = + - Mass , Momentum, Energy #12

  19. Generation IV benchmarking of TRISO fuel performance models under accident conditions. Modeling input data

    SciTech Connect (OSTI)

    Blaise Collin

    2014-09-01

    This document presents the benchmark plan for the calculation of particle fuel performance on safety testing experiments that are representative of operational accidental transients. The benchmark is dedicated to the modeling of fission product release under accident conditions by fuel performance codes from around the world, and the subsequent comparison to post-irradiation experiment (PIE) data from the modeled heating tests. The accident condition benchmark is divided into three parts: the modeling of a simplified benchmark problem to assess potential numerical calculation issues at low fission product release; the modeling of the AGR-1 and HFR-EU1bis safety testing experiments; and, the comparison of the AGR-1 and HFR-EU1bis modeling results with PIE data. The simplified benchmark case, thereafter named NCC (Numerical Calculation Case), is derived from ''Case 5'' of the International Atomic Energy Agency (IAEA) Coordinated Research Program (CRP) on coated particle fuel technology [IAEA 2012]. It is included so participants can evaluate their codes at low fission product release. ''Case 5'' of the IAEA CRP-6 showed large code-to-code discrepancies in the release of fission products, which were attributed to ''effects of the numerical calculation method rather than the physical model''[IAEA 2012]. The NCC is therefore intended to check if these numerical effects subsist. The first two steps imply the involvement of the benchmark participants with a modeling effort following the guidelines and recommendations provided by this document. The third step involves the collection of the modeling results by Idaho National Laboratory (INL) and the comparison of these results with the available PIE data. The objective of this document is to provide all necessary input data to model the benchmark cases, and to give some methodology guidelines and recommendations in order to make all results suitable for comparison with each other. The participants should read this document thoroughly to make sure all the data needed for their calculations is provided in the document. Missing data will be added to a revision of the document if necessary.

  20. Delayed energy injection model for gamma-ray burst afterglows

    SciTech Connect (OSTI)

    Geng, J. J.; Huang, Y. F.; Yu, Y. B. [Department of Astronomy, Nanjing University, Nanjing 210093 (China); Wu, X. F., E-mail: hyf@nju.edu.cn, E-mail: xfwu@pmo.ac.cn [Purple Mountain Observatory, Chinese Academy of Sciences, Nanjing 210008 (China)

    2013-12-10

    The shallow decay phase and flares in the afterglows of gamma-ray bursts (GRBs) are widely believed to be associated with the later activation of the central engine. Some models of energy injection involve a continuous energy flow since the GRB trigger time, such as the magnetic dipole radiation from a magnetar. However, in the scenario involving a black hole accretion system, the energy flow from the fall-back accretion may be delayed for a fall-back time ?t {sub fb}. Thus, we propose a delayed energy injection model. The delayed energy would cause a notable rise to the Lorentz factor of the external shock, which will 'generate' a bump in the multiple band afterglows. If the delayed time is very short, our model degenerates to the previous models. Our model can explain the significant re-brightening in the optical and infrared light curves of GRB 081029 and GRB 100621A. A considerable fall-back mass is needed to provide the later energy; this indicates that GRBs accompanied with fall-back material may be associated with a low energy supernova so that the fraction of the envelope can survive during eruption. The fall-back time can give meaningful information on the properties of GRB progenitor stars.