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Sample records for ms ashley armstrong

  1. To: Ashley Armstrong, U.S. Department of Energy From: Amy Shepherd, General Counsel, AHRI

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    October 19, 2015 To: Ashley Armstrong, U.S. Department of Energy From: Amy Shepherd, General Counsel, AHRI Re: Ex Parte Communication on Central Air-Conditioner Test Procedure - ICM Issues On October 8, 2015, AHRI staff and Independent Coil Manufacturer (ICM) Representatives met with a representative from the Department of Energy (DOE) to discuss proposed amended test procedures for central air conditioners and how they would impact ICM manufacturers. The meeting was held at AHRI offices in

  2. Sheila Armstrong

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Sheila Armstrong Sheila Armstrong-Helping hospice patients and their loved ones say good-bye Sheila Armstrong of the X Theoretical Design Division began her Laboratory career in 1972 but in the 1990s took a break and trained to become a hospice volunteer. October 7, 2014 Sheila Armstrong Sheila Armstrong takes a well-deserved break among the trees. "At the end, everyone wants to feel that they made a difference, so my visits with patients often include tape-recording stories about their

  3. ashleye1 | The Ames Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ashleye1 Ames Laboratory Profile Ashley Augspurger Grad Asst-RA Chemical & Biological Sciences 122 Spedding Phone Number: 515-294-7568 Email Address: ashleye1

  4. Jason Armstrong

    Broader source: Energy.gov [DOE]

    Jason Armstrong is the Director of Operations for the Oak Ridge Office of Environmental Management.  The mission of the Operations Division is to provide oversight of contractor operations at...

  5. Andy Armstrong

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Andy Armstrong - Sandia Energy Energy Search Icon Sandia Home Locations Contact Us Employee Locator Energy & Climate Secure & Sustainable Energy Future Stationary Power Energy Conversion Efficiency Solar Energy Wind Energy Water Power Supercritical CO2 Geothermal Natural Gas Safety, Security & Resilience of the Energy Infrastructure Energy Storage Nuclear Power & Engineering Grid Modernization Battery Testing Nuclear Energy Defense Waste Management Programs Advanced Nuclear

  6. Ashley Cadby | Photosynthetic Antenna Research Center

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Ashley Cadby Ashley Cadby Ashley Cadby Ashley Cadby Senior Lecturer E-mail: a.cadby@sheffield.ac.uk Phone: +44 114 222 4295 Website: University of Sheffield Bio Research and...

  7. ATTENDEEES: Ashley Armstrong, DOE Laura Barhydt DOE Eric Stas...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Carnevale, Bradford White Corporation Mark Taylor, Bradford White Corporation Adam S. Olsen, Sconset Strategies, LLC on behalf of Bradford White Corporation MEETING DATE: Tuesday, ...

  8. ATTENDEES: Ashley Armstrong, Department of Energy Laura Barhydt...

    Broader source: Energy.gov (indexed) [DOE]

    Manufacturing Company- Fort Smith, AR Ted Schroder, Alston & Bird, on Behalf of Rheem Manufacturing Company- Washington, D.C. Josh Greene, AO Smith- Milwaukee Wisconsin Greg ...

  9. ORISE: Undergraduate Research Experiences - Ashley Cross

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Ashley Cross SULI participant modifies DNA to amp up ethanol production Ashley Cross at ORNL SULI participant Ashley Renee Cross used her bachelor's degree in biology to explore the DNA behind ethanol production and how bioengineering can improve biofuel yields. Ashley Renee Cross spent 16 weeks engineering something smaller than all the flakes of snow and points of pollen floating in the air: microorganisms. With mutant strains under the microscope, Cross, alongside her mentor Dr. Adam Guss,

  10. David Armstrong | Photosynthetic Antenna Research Center

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Armstrong David Armstrong David Armstrong Alumnus Dr. Armstrong completed his PhD under PARC PI Neil Hunter and is currently a staff member of the Bioinformatics Institute, Cambridge, United Kingdom

  11. Ashley Boyle | Argonne Leadership Computing Facility

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Ashley Boyle Administrative Secretary Argonne National Laboratory 9700 South Cass Avenue Building 240 - Wkstn. 3D16 Argonne, IL 60439 630-252-1385 aboyle@anl

  12. Ringleader: Ashley White, Director of Communications

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Ashley White, Director of Communications Print After many years as a researcher followed by a few in government and policy, Ashley White sees her new position as ALS Director of Communications as a perfect blend of it all. "I'm thrilled to be back in a research environment, since I started out my career as a researcher and loved being in the lab," she says. "When I walk around the ALS and see all the tin foil and the beamline equipment, it feels like home." After completing

  13. Armstrong Energy Pvt Ltd | Open Energy Information

    Open Energy Info (EERE)

    Energy Pvt Ltd Jump to: navigation, search Name: Armstrong Energy Pvt. Ltd. Place: Mumbai, Maharashtra, India Zip: 400 010 Sector: Biomass Product: Mumbai-based biomass project...

  14. SSLS Scientist Andy Armstrong Receives 2013 Employee Recognition Award

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Scientist Andy Armstrong Receives 2013 Employee Recognition Award - Sandia Energy Energy Search Icon Sandia Home Locations Contact Us Employee Locator Energy & Climate Secure & Sustainable Energy Future Stationary Power Energy Conversion Efficiency Solar Energy Wind Energy Water Power Supercritical CO2 Geothermal Natural Gas Safety, Security & Resilience of the Energy Infrastructure Energy Storage Nuclear Power & Engineering Grid Modernization Battery Testing Nuclear Energy

  15. Alternative schemes for production of chilled water and cogeneration of electricity at Ashley Plant

    SciTech Connect (OSTI)

    Not Available

    1989-01-01

    William Tao Associates, Inc. (TAO) evaluated alternative systems for the generation of Chilled Water at Ashley Plant. The generation of chilled water is necessary for several reason; initially as a source of revenue for St. Louis Thermal Energy Corporation (SLTEC), but more importantly as a necessary component of the Trash-to-Energy Plant proposed north of Ashley Plant. The chilled water system provides a base load for steam generated by the Trash-to-Energy Plant. The benefits include reduced tip-fees to the City of St. Louis, lower cost of energy to customers of both the district steam system and the proposed chilled water system, and will result in lower energy and operating costs for the system than if individual services are provided. This symbiotic relationship is main advantage of the Trash-to-Energy system. TAO provided preliminary engineering of the chilled water line route. The basic assumptions of an initial load of 10,000 tons with an ultimate load of 20,000 tons at a temperature difference of 16{degree}F remain. The findings of the pipeline study, although not incorporated into this document, remain valid. Assumptions include the following: An initial design load of 6000 tons which has the capability of growing to 20,000 tons; Incremental costs of steam generated by Ashley Plant and the Trash-to-Energy plant; The turbine room at Ashley Plant is suitable for gut rehab except for turbines No. 7 and No. 9 which should remain operational; and Daily chilled water flow and annual load profile. The paper describes the findings on 8 alternative chiller systems. Additional studies were performed on the following: chilled water storage; low-pressure absorption chiller for balancing plant steam loads; economizer cycle for chiller system; auxiliary equipment energy source; variable flow water pumps; and comparison to satellite chilled water plant study.

  16. Microsoft Word - Document1

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Greg Coulter [mailto:greg.coulter405@gmail.com] Sent: Friday, October 29, 2010 4:13 PM To: Barhydt, Laura Cc: Armstrong, Ashley; Leon Chapa Ismael Ricardo (GE Infra Energy Subject: GE-Prolec CCE Meeting October 19,2010 Ms. Barhydt, This e-mail documents the GE-Prolec CCE meeting of October 19, 2010 concerning Docket No. EERE-2010-BT-CE-0014. Mr. Ismael Leon and myself met with Ms. Ashley Armstrong, Ms. Celia Sher, Ms. Stephanie Weiner, and Ms. Laura Barhydt in your offices and discussed the

  17. Sheila Armstrong

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    may consist of a doctor, nurses, nurses' aides, a social worker, a massage therapist, a music therapist and volunteers like me. - 2 - I provide much-needed respites for family...

  18. Microsoft Word - Ex Parte Memo re Walk-in Coolers

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    The following individuals were present or on the telephone: John Cymbalsky, DOE Dan Cohen, DOE Ashley Armstrong, DOE Michael Kido, DOE Benjamin Longstreth, NRDC Joanna Mauer, ASAP ...

  19. Appliance Standards and Building Codes

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... Team Lead - Test Procedures and Certification, Compliance, and Enforcement Ashley Armstrong, (202) 586-6590 * Lucas Adin, (202) 287-1317 * Bryan Berringer, (202) 586-0371 * Josh ...

  20. Process Simulation of Cold Pressing and Sintering of Armstrong CP-Ti Powders

    SciTech Connect (OSTI)

    Gorti, Sarma B; Sabau, Adrian S; Peter, William H; Nunn, Stephen D; Yamamoto, Yukinori; Chen, Wei

    2011-01-01

    A computational methodology is presented for the process simulation of cold pressing and sintering of Armstrong CP-Ti powders. Since the powder consolidation is governed by specific pressure-dependent constitutive equations, solution algorithms were developed for the ABAQUS user material subroutine, UMAT, for computing the plastic strain increments based on an implicit integration of the nonlinear yield function, flow rule, and hardening equations. Sintering was simulated using a model based on diffusional creep using the user subroutine CREEP. The initial mesh, stress, and density for the simulation of sintering were obtained from the results of the cold pressing simulation, minimizing the errors from decoupling the cold pressing and sintering simulations. Numerical simulation results are presented for the cold compaction followed by a sintering step of the Ti powders. The numerical simulation results for the relative density were compared to those measured from experiments before and after sintering, showing that the relative density can be accurately predicted. Notice: This manuscript has been authored by UT-Battelle, LLC, under Contract No. DE-AC05-00OR22725 with the U.S. Department of Energy. The United States Government retains and the publisher, by accepting the article for publication, acknowledges that the United States Government retains a non-exclusive, paid-up, irrevocable, world-wide license to publish or reproduce the published form of this manuscript, or allow others to do so, for United States Government purposes. ACKNOWLEDGEMENTS This research was sponsored by the U.S. DOE, and carried out at ORNL, under Contract DE-AC05-00OR22725 with UT-Battelle, LLC. This research was sponsored by the U.S. DOE, EERE Industrial Technology Program Office under CPS Agreement # 17881.

  1. Sandia Energy Ashley Otero

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Detecting rare, abnormally large grains by x-ray diffraction http:energy.sandia.govdetecting-rare-abnormally-large-grains-by-x-ray-diffraction http:energy.sandia.gov...

  2. UL Ex Parte communications | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    UL Ex Parte communications UL Ex Parte communications On December 27, I was contacted by Ms. Ashley Armstrong, U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, Building Technologies Program and asked if I would be willing to meet with her and certain US DOE staff to discuss UL's "different testing and certification offerings as they relate to electric motors". Ex parte comm_1_7_2013.pdf (77.46 KB) More Documents & Publications ex parte communication

  3. Untitled.pdf

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    EERE-2012-BT-STD-0041. The attendees were: Ashley Armstrong, DOE Laura Barhydt, DOE Nathan Cardon, Keller and Heckman LLP David Case, DOE John Cymbalsky, DOE Daniel Cohen, DOE ...

  4. MS/MS Automated Selected Ion Chromatograms

    Energy Science and Technology Software Center (OSTI)

    2005-12-12

    This program can be used to read a LC-MS/MS data file from either a Finnigan ion trap mass spectrometer (.Raw file) or an Agilent Ion Trap mass spectrometer (.MGF and .CDF files) and create a selected ion chromatogram (SIC) for each of the parent ion masses chosen for fragmentation. The largest peak in each SIC is also identified, with reported statistics including peak elution time, height, area, and signal to noise ratio. It creates severalmore » output files, including a base peak intensity (BPI) chromatogram for the survey scan, a BPI for the fragmentation scans, an XML file containing the SIC data for each parent ion, and a "flat file" (ready for import into a database) containing summaries of the SIC data statistics.« less

  5. LA-983%MS

    Office of Legacy Management (LM)

    LA-983%MS p 1);: 3 -: ,,i .' . , , -- .. >: 1.. . bob l,,,o* atlonal t&,oratov is operated by the University of California for the United States Department of Energy under ...

  6. Ms. Maria Galanti

    Broader source: Energy.gov (indexed) [DOE]

    ... LPPIPORTS Administrative Record - CERCLA PPPO RecordsILEX PPP03-112943S-11 Ms. Maria Galanti Department of Energy PortsmouthPaducah Project Office 1017 Majestic Drive, Suite 200 ...

  7. LA-11224-MS

    Office of Scientific and Technical Information (OSTI)

    and UC-70 Issued: March 1988 LA--112 2 4-MS DE88 005902 FEHM: Finite Element Heat and Mass Transfer Code George Zyvoloski Zora Dash Sharad Kelkar DISCLAIMER This report was ...

  8. MS Based Metabonomics

    SciTech Connect (OSTI)

    Want, Elizabeth J.; Metz, Thomas O.

    2010-03-01

    Metabonomics is the latest and least mature of the systems biology triad, which also includes genomics and proteomics, and has its origins in the early orthomolecular medicine work pioneered by Linus Pauling and Arthur Robinson. It was defined by Nicholson and colleagues in 1999 as the quantitative measurement of perturbations in the metabolite complement of an integrated biological system in response to internal or external stimuli, and is often used today to describe many non-global types of metabolite analyses. Applications of metabonomics are extensive and include toxicology, nutrition, pharmaceutical research and development, physiological monitoring and disease diagnosis. For example, blood samples from millions of neonates are tested routinely by mass spectrometry (MS) as a diagnostic tool for inborn errors of metabolism. The metabonome encompasses a wide range of structurally diverse metabolites; therefore, no single analytical platform will be sufficient. Specialized sample preparation and detection techniques are required, and advances in NMR and MS technologies have led to enhanced metabonome coverage, which in turn demands improved data analysis approaches. The role of MS in metabonomics is still evolving as instrumentation and software becomes more sophisticated and as researchers realize the strengths and limitations of current technology. MS offers a wide dynamic range, high sensitivity, and reproducible, quantitative analysis. These attributes are essential for addressing the challenges of metabonomics, as the range of metabolite concentrations easily exceeds nine orders of magnitude in biofluids, and the diversity of molecular species ranges from simple amino and organic acids to lipids and complex carbohydrates. Additional challenges arise in generating a comprehensive metabolite profile, downstream data processing and analysis, and structural characterization of important metabolites. A typical workflow of MS-based metabonomics is shown in Figure

  9. Ms. Maggie Owen, Chair

    Office of Environmental Management (EM)

    8, 2013 Ms. Brenda Edwards U.S. Department of Energy, Buildings Technology Program Mail Stop EE-2J 1000 Independence Ave. SW Washington DC 20585-0121 RE: Revisions to Energy Efficiency Enforcement Regulations EERE-2011-BT-TD- 0005 Dear Ms. Edwards: The National Marine Manufacturers Association (NMMA) appreciates the opportunity to respond to the Department of Energy (DOE), Office of Energy Efficiency and Renewable Energy's request for information published in the Federal Register (78 Fed. Reg.

  10. IMS - MS Data Extractor

    Energy Science and Technology Software Center (OSTI)

    2015-10-20

    An automated drift time extraction and computed associated collision cross section software tool for small molecule analysis with ion mobility spectrometry-mass spectrometry (IMS-MS). The software automatically extracts drift times and computes associated collision cross sections for small molecules analyzed using ion mobility spectrometry-mass spectrometry (IMS-MS) based on a target list of expected ions provided by the user.

  11. ICP-MS Workshop

    SciTech Connect (OSTI)

    Carman, April J.; Eiden, Gregory C.

    2014-11-01

    This is a short document that explains the materials that will be transmitted to LLNL and DNN HQ regarding the ICP-MS Workshop held at PNNL June 17-19th. The goal of the information is to pass on to LLNL information regarding the planning and preparations for the Workshop at PNNL in preparation of the SIMS workshop at LLNL.

  12. Ms. Maria Galanti

    Office of Environmental Management (EM)

    HAR 2 4 lDII Ohio Environmental Protection Agency Southeast District Office 2195 Front Street Logan, Ohio 43138 Dear Ms. Galanti: PPPO-03-1158259-11 CONSTRUCTION COMPLETION REPORT FOR REMOVAL OF THE X-533 SWITCHYARD COMPLEX AT THE PORTSMOUTH GASEOUS DIFFUSION PLANT, PIKETON, OHIO The Department of Energy is submitting the enclosed Construction Completion Report for Removal of the X-533 Switchyard Complex at the Portsmouth Gaseous Diffusion Plant, Piketon, Ohio (DOEIPPPO/03-0174&D1) to the

  13. MS, II-J

    Office of Legacy Management (LM)

    I' ; ,' Departm&th of Energy 1 MS, II-J Washington. DC 20585 ' . I I The Honorable John Gallagher ,)fl', /',' ' 103 E. Michigan Avenue .i., ,.' Battle Creek, Michigan 49016 _. Dear Mayor Gallagheri d,---, " '/ approachto openness i.n: with the: public. In (FUSRAP)i.is responsible agencies, determining ~author~ity, performing remedial action to cleanup sites to meet current radiological protection requirements.. A conservative set of technical evaluation guidelines is used in these

  14. In-Situ Radiological Surveys to Address Nuclear Criticality Safety Requirements During Remediation Activities at the Shallow Land Disposal Area, Armstrong County, Pennsylvania - 12268

    SciTech Connect (OSTI)

    Norris, Phillip; Mihalo, Mark; Eberlin, John; Lambert, Mike; Matthews, Brian

    2012-07-01

    Cabrera Services Inc. (CABRERA) is the remedial contractor for the Shallow Land Disposal Area (SLDA) Site in Armstrong County Pennsylvania, a United States (US) Army Corps of Engineers - Buffalo District (USACE) contract. The remediation is being completed under the USACE's Formerly Utilized Sites Remedial Action Program (FUSRAP) which was established to identify, investigate, and clean up or control sites previously used by the Atomic Energy Commission (AEC) and its predecessor, the Manhattan Engineer District (MED). As part of the management of the FUSRAP, the USACE is overseeing investigation and remediation of radiological contamination at the SLDA Site in accordance with the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), 42 US Code (USC), Section 9601 et. seq, as amended and, the National Oil and Hazardous Substance Pollution Contingency Plan (NCP), Title 40 of the Code of Federal Regulations (CFR) Section 300.430(f) (2). The objective of this project is to clean up radioactive waste at SLDA. The radioactive waste contains special nuclear material (SNM), primarily U-235, in 10 burial trenches, Cabrera duties include processing, packaging and transporting the waste to an offsite disposal facility in accordance with the selected remedial alternative as defined in the Final Record of Decision (USACE, 2007). Of particular importance during the remediation is the need to address nuclear criticality safety (NCS) controls for the safe exhumation and management of waste containing fissile materials. The partnership between Cabrera Services, Inc. and Measutronics Corporation led to the development of a valuable survey tool and operating procedure that are essential components of the SLDA Criticality Safety and Material Control and Accountability programs. Using proven existing technologies in the design and manufacture of the Mobile Survey Cart, the continued deployment of the Cart will allow for an efficient and reliable methodology to

  15. LA-13859-MS

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    13859-MS Issued: September 2001 Nevada Test Site Radionuclide Inventory, 1951-1992 Scott M. Bowen David L. Finnegan Joseph L. Thompson Charles M. Miller (Deceased) Phyllis L. Baca Loretta F. Olivas Carmen G. Geoffrion David K. Smith* Wataru Goishi* Bradley K. Esser* Jesse W. Meadows* Neil Namboodiri* John F. Wild* *Lawrence Livermore National Laboratory, 7000 East Ave., Livermore, CA 94550-9234 Los Alamos N A T I O N A L L A B O R A T O R Y Los Alamos, New Mexico 87545 Nevada Test Site

  16. Ringleader: Ashley White, Director of Communications

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    like home." After completing her PhD in Materials Science from the University of Cambridge, White says she was looking for something "a little bit different" and heard about...

  17. Video:Ashley Anderson and Amber Stoesser

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Video: Watch the Open Data Google+ Hangout Video: Watch the Open Data Google+ Hangout February 21, 2013 - 5:10pm Addthis Did you miss our open data hangout? View it here. Matthew Loveless Matthew Loveless Data Integration Specialist, Office of Public Affairs Want more info? Check out these open data resources. Thank you to everyone who tuned in to our Google+ Hangout on the "Impact of Open Data." If you weren't able to attend, a recording of the discussion is available above. We hope

  18. METLIN: MS/MS metabolite data from the MAGGIE Project

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    METLIN is a metabolite database for metabolomics containing over 50,000 structures, it also represents a data management system designed to assist in a broad array of metabolite research and metabolite identification by providing public access to its repository of current and comprehensive MS/MS metabolite data. An annotated list of known metabolites and their mass, chemical formula, and structure are available on the METLIN website. Each metabolite is conveniently linked to outside resources such as the the Kyoto Encyclopedia of Genes and Genomes (KEGG) for further reference and inquiry. MS/MS data is also available on many of the metabolites. The list is expanding continuously as more metabolite information is being deposited and discovered. [from http://metlin.scripps.edu/] Metlin is a component of the MAGGIE Project. MAGGIE is funded by the DOE Genomics: GTL and is an acronym for "Molecular Assemblies, Genes, and Genomics Integrated Efficiently."

  19. Ms. Susan Leckband, Chair W

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    MAR 1 9 2009 Ms. Susan Leckband, Chair W o r d Advisory Board 713 Jadwin, Suite 4 achland, WA 99352 Dear Ms. Leckband: Thank you for your letter dated December 5,2008, providing the Hanford Advisory Bbard's (Board) Consensus Advice #211. I appreciate the Board's participation and counsel during the meetings to discuss the future of the Hanford Site cleanup program as well as the recommendations contained in your letter. I wish to assure you that the Board will continue to be consulted, through

  20. Ms. Maria Galanti Site Coordinator

    Office of Environmental Management (EM)

    DEC 23 ZDto PPPO-03-1088949-11 Ohio Environmental Protection Agency 2195 Front Street Logan, Ohio 43138 Dear Ms. Galanti: REVISED CONSTRUCTION COMPLETION REPORT FOR PHASE I OF THE REMOVAL OF THE X-633 RECIRCULATING COOLING WATER COMPLEX AT THE PORTSMOUTH GASEOUS DIFFUSION PLANT, PIKETON, OHIO AND RESPONSES TO COMMENTS The Department of Energy is SUbmitting the enclosed revised Construction Completion Report for Phase I of the Removal of the X-633 ReCirculating Cooling Water Complex at the

  1. Ms. Maria Galanti Site Coordinator

    Office of Environmental Management (EM)

    3 0 2015 Ohio Environmental Protection Agency Southeast District Office 2195 Front Street Logan, Ohio 43138 Dear Ms. Galanti: PPP0-03-3065331-15 FINAL RECORD OF DECISION FOR THE PROCESS BUILDINGS AND COMPLEX FACILITIES DECONTAMINATION AND DECOMMISSIONING EVALUATION PROJECT AT THE PORTSMOUTH GASEOUS DIFFUSION PLANT, PIKETON, OHIO (DOE/PPP0/03-0425&Dl) References: 1. Letter from W. Murphie to M. Galanti, "Record of Decision for the Process Buildings and Complex Facilities Decontamination

  2. LA-5097-MS INFORMAL REPORT

    Office of Legacy Management (LM)

    5097-MS INFORMAL REPORT lamos lamos scientific laboratory scientific laboratory of the University of California of the University of California LOS ALAMOS. NEW MEXICO 87544 LOS ALAMOS. NEW MEXICO 87544 Los AIamos Land Areas Environmental Radiation Survey 1972 . In the interest of prompt distribution, this LAMS re port was not edited by the Technical Information staff. Printed in the United States of America. Available from National Technical Information Service U. S. Department of Commerce 5285

  3. Category:Jackson, MS | Open Energy Information

    Open Energy Info (EERE)

    Jackson, MS Jump to: navigation, search Go Back to PV Economics By Location Media in category "Jackson, MS" The following 16 files are in this category, out of 16 total....

  4. Ms. Maria Galanti Site Coordinator

    Office of Environmental Management (EM)

    ? 5 2011 PPPO-03-1251788-11 Ohio Environmental Protection Agency Southeast District Office 2195 Front Street Logan, Ohio 43138 Dear Ms. Galanti: TRANSMITTAL OF Dl CONSTRUCTION COMPLETION REPORT FOR PHASES I AND II OF THE REMOVAL OF THE X-760 CHEMICAL ENGINEERING BUILDING AT THE PORTSMOUTH GASEOUS DIFFUSION PLANT, PIKETON, OHIO (DOE/PPPO/03-0196&Dl) Reference: Letter from M. Galanti to J. Bradbume, "Construction Completion Report for Phases I and II ofthe Removal of the X-760 Chemical

  5. Wardell Armstrong International | Open Energy Information

    Open Energy Info (EERE)

    Product: Provides consultancy and technical services for aquifer geothermal, wind, waste to energy and biomass projects. Coordinates: 50.443321, -4.93986 Show Map Loading...

  6. ARM - Campaign Instrument - ptr-ms

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    would love to hear from you Send us a note below or call us at 1-888-ARM-DATA. Send Campaign Instrument : Proton Transfer Reaction Mass Spectrometer (PTR-MS) Instrument...

  7. Enerkem Mississippi Biofuels Pontotoc, MS Facility

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Enerkem Mississippi Biofuels Pontotoc, MS Facility 2013 IBR Peer Review May 21 st , 2013 ... as part of the first wave of advanced biofuels projects in the U.S. The advanced and ...

  8. ARM - Campaign Instrument - pyran-eko-ms-801

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    eko-ms-801 Comments? We would love to hear from you! Send us a note below or call us at 1-888-ARM-DATA. Send Campaign Instrument : Pyranometer-eko-ms-801 (PYRAN-EKO-MS-801

  9. Mr. Christopher Lawrence and Ms. Julie Smith Office of Electricity...

    Broader source: Energy.gov (indexed) [DOE]

    Mr. Christopher Lawrence and Ms. Julie Smith Office of Electricity Delivery and Energy ... Lawrence and Ms. Smith, The Western Governors' Association (WGA) is submitting these ...

  10. LC-IMS-MS Feature Finder

    Energy Science and Technology Software Center (OSTI)

    2013-03-07

    LC-IMS-MS Feature Finder is a command line software application which searches for possible molecular ion signatures in multidimensional liquid chromatography, ion mobility spectrometry, and mass spectrometry data by clustering deisotoped peaks with similar monoisotopic mass values, charge states, elution times, and drift times. The software application includes an algorithm for detecting multiple conformations and co-eluting species in the ion mobility dimension. LC-IMS-MS Feature Finder is designed to create an output file with detected features thatmore » includes associated information about the detected features.« less

  11. LC-IMS-MS Feature Finder

    SciTech Connect (OSTI)

    2013-03-07

    LC-IMS-MS Feature Finder is a command line software application which searches for possible molecular ion signatures in multidimensional liquid chromatography, ion mobility spectrometry, and mass spectrometry data by clustering deisotoped peaks with similar monoisotopic mass values, charge states, elution times, and drift times. The software application includes an algorithm for detecting multiple conformations and co-eluting species in the ion mobility dimension. LC-IMS-MS Feature Finder is designed to create an output file with detected features that includes associated information about the detected features.

  12. MS-DM Nexus poster 081716

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Materials Science and Data Technology Nexus mini-symposium mini-symposium is 
 aligned with the CINT 2016 User Meeting, September 19 - 20. 
 You are encouraged to attend the CINT user workshop as well, as your schedule permits. Please go to https://conferences.newmexicoconsortium.org/ to register for both the CINT User Meeting and MS/DT Nexus.
 MS/DT Nexus registration fees will cover the mini-symposium talks, meals, and the evening reception on the 21st. Scope: Recent years have witnessed

  13. From: Ashley Foreman To: Congestion Study Comments Subject:

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    The compensation cannot begin to cover the all of the losses, tangible and intangible that ... Third, the eastern states should develop the utility scale wind resources conveniently ...

  14. Analysis of Phosphonic Acids: Validation of Semi-Volatile Analysis by HPLC-MS/MS by EPA Method MS999

    SciTech Connect (OSTI)

    Owens, J; Vu, A; Koester, C

    2008-10-31

    The Environmental Protection Agency's (EPA) Region 5 Chicago Regional Laboratory (CRL) developed a method titled Analysis of Diisopropyl Methylphosphonate, Ethyl Hydrogen Dimethylamidophosphate, Isopropyl Methylphosphonic Acid, Methylphosphonic Acid, and Pinacolyl Methylphosphonic Acid in Water by Multiple Reaction Monitoring Liquid Chromatography/Tandem Mass Spectrometry: EPA Version MS999. This draft standard operating procedure (SOP) was distributed to multiple EPA laboratories and to Lawrence Livermore National Laboratory, which was tasked to serve as a reference laboratory for EPA's Environmental Reference Laboratory Network (ERLN) and to develop and validate analytical procedures. The primary objective of this study was to validate and verify the analytical procedures described in EPA Method MS999 for analysis of the listed phosphonic acids and surrogates in aqueous samples. The gathered data from this validation study will be used to: (1) demonstrate analytical method performance; (2) generate quality control acceptance criteria; and (3) revise the SOP to provide a validated method that would be available for use during a homeland security event. The data contained in this report will be compiled, by EPA CRL, with data generated by other EPA Regional laboratories so that performance metrics of EPA Method MS999 can be determined.

  15. CONCURRENC RTG. SYMBOL GC-34 Ms. Mary Beth Brado

    Office of Legacy Management (LM)

    MAY 2 9 1980 CONCURRENC RTG. SYMBOL GC-34 Ms. Mary Beth Brado "*N'W Town of Lewiston * i.., 1375 Ridge Road r'8 Lewiston, New York 14092 RTG.SYuBOL Dear Ms. Brado: .- ,l13. ...

  16. Bioenergia Brasil S A MS | Open Energy Information

    Open Energy Info (EERE)

    Brasil S A MS Jump to: navigation, search Name: Bioenergia Brasil SA (MS) Place: Mato Grosso do Sul, Brazil Product: Company developing a 100m litre per year ethanol plant in Mato...

  17. LA--12O48-MS DE91

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    -12O48-MS DE91 010299 I ~ I i Tm Thou.mwl Yews of Solitude? 0)1 llzfuhwh!lll Illfrlwiml i)ffo fhc Wmtefsolfltiwl Pilot Project Rqwsitory GrL~gor!/B L')/fo)"(i* Craig W. Kirhood** HmwjOfwf7y Marfit~/. Pmquak!!i+ ~~~~n~~~~L..Al...s.Me. M.xico 87541 L A N L % D I O T D I U E Table of Contents Preface . . . . . . . . . . . . . . . . . . . . . . . . . . .. .. .. .. .. .. .. D O . . . . . . . . . . . ...ooOO.OO..OOOOO"OO".OO """"."" 'ti 1. Introduction . .

  18. Update and Overview of the U.S. Department of Energy's Rulemakings for ASHRAE 90.1 Equipment Presentation, dated June 26, 2011

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Program eere.energy.gov BUILDING TECHNOLOGIES PROGRAM Update and Overview of DOE Rulemakings for ASHRAE 90.1 Equipment Ashley Armstrong Department of Energy Energy Efficiency & Renewable Energy 6/26/2011 Introduction and Background 1 Introduction and Background Status of Current DOE ASHRAE 90.1 Equipment Rulemaking 2 Update and Overview for Individual ASHRAE 90.1 Equipment Types 3 2 | Building Technologies Program eere.energy.gov Introduction and Background * The "ASHRAE Trigger":

  19. CANADA-UNITED STATES REGULATORY COOPERATION COUNCIL

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    CANADA-UNITED STATES REGULATORY COOPERATION COUNCIL Webinar: Proposed Approach for Energy Efficiency Standards January 12, 2015 Natural Resources Ressources naturelles Canada Canada Key Contacts in U.S. and Canada NRCan * Debbie Scharf, Director of Equipment Division * Katherine Delves, Chief of Standards Development * Jamie Hulan, Team leader for Standards Development * Andrés Drew, RCC lead DOE * John Cymbalsky, Program Manager for Appliance Standards * Ashley Armstrong, Supervisory

  20. The International Authority on Air Movement Systems

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    International Authority on Air Movement Systems TO: expartecommunications@hq.doe.gov (sent via email) CC: Ashley.Armstrong@ee.doe.gov FROM: Mark Stevens, Executive Director of AMCA International DATE: November 9, 2015 RE: Memorandum Memorializing Ex Parte Communication, November 9, 2015 related to DOE impending coverage for commercial and industrial fans, blowers, and fume hoods, Docket No. EERE---2011---BT---DET---0045. Meeting Purpose: The meeting was requested by AMCA International to inform

  1. Memorandum for Chief Acquisition Officers, Senior Procurement Executives

    Office of Environmental Management (EM)

    GENERAL COUNSEL, DEPARTMENT OF ENERGY (DOE) From: JONATHAN MELCHI, HEATING, AIR-CONDITIONING AND REFRIGERATION DISTRIBUTORS INTERNATIONAL (HARDI) Date: 1/12/2012 Subject: EX PARTE COMMUNICATION MEMO DOE ATTENDEES: Ashley Armstrong, John Cymbalsky, David Case, Laura Barhydt HARDI ATTENDEES: Talbot Gee, Jonathan Melchi AREAS OF DISCUSSION: DOE Framework Document and Stakeholder Meeting regarding the Enforcement of the updated Energy Conservation Standards for Air Conditioners, Furnaces and Heat

  2. Workshop on Condensing Heating and Water Heating Equipment

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Workshop on Condensing Heating and Water Heating Equipment Thursday, October 9, 2014 List of Attendees Organization/Attendees DOE - John Cymbalsky - Ashley Armstrong - Johanna Hariharan AGA - Kathryn Clay - Rick Murphy - Lisa Dundon APGA - Dave Schryver - Bud Miller Gas Technology Institute - Neil Leslie Washington Gas Light - Melissa Adams - Kevin Dunn ACEEE - Harvey Sachs ASAP - Andrew deLaski ASE - Rodney Sobin NRDC - Elizabeth Noll AHRI - Frank Stanonik ACCA - Charlie McCrudden - Glenn

  3. Ex Parte Memo_September 25, 2013_Kitable (00019672).DOC

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    June 29, 2016 subject: Ex parte Communication; Docket No. EERE-2011-BT-DET-0072 This memo memorializes the meeting between AHAM and the Department of Energy on May 3, 2016, for inclusion in the public docket. In summary, we discussed AHAM's comments on DOE's Supplemental Notice of Proposed Determination of Miscellaneous Refrigeration Products as Covered Products; Docket No. EERE-2011-BT-DET-0072; RIN 1904-AC51, 81 Fed. Reg., 11454 (March 4, 2016). The attendees were as follows: Ashley Armstrong,

  4. Ex Parte Memo_September 26, 2013_RF TP Icemaker Comments (00031507).DOC

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    January 31, 2014) on DOE's Notice of Proposed Rulemaking on Test Procedures for Refrigerators, Refrigerator-Freezers, and Freezers, Docket No. EERE-2012-BT- TP-0016, RIN 1904-AC76. The attendees were as follows: Ashley Armstrong, DOE Laura Barhydt, DOE John Cymbalsky, DOE Michael Kido, DOE Tim Sutherland, Navigant Bill Brown, GE Appliances and Lighting Andrew Krause, GE Appliances and Lighting Travis Perkins, Whirlpool Corporation (phone) Jennifer Cleary, AHAM Sriram Gopal

  5. Ex Parte Memo_September 26, 2014_PAC TP Comments (00031509).DOC

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    June 9, 2014) on DOE's Notice of Data Availability for Portable Air Conditioners, Docket No. EERE-2014-BT-TP-0014, RIN 1904-AD22. The attendees were as follows: Ashley Armstrong, DOE Laura Barhydt, DOE Tim Sutherland, Navigant Mike Prager, De'Longhi USA Paolo Rognini, De'Longhi USA Stefano Vit, De'Longhi Jennifer Cleary, AHAM Sriram Gopal, AHAM Steve Leybourn, AHAM Wayne Morris

  6. Ex-Parte Meeting Summary | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Ex-Parte Meeting Summary Ex-Parte Meeting Summary On December 12, 2011 a meeting was held amongst Wes Anderson (DOE), Ashley Armstrong (DOE), and J.B. Hoyt (Whirlpool Corporation). cooking_products_def_issue.pdf (70.74 KB) More Documents & Publications Disclosure of Ex Parte Communication Lutron Electronics Co., Inc. ex-parte meeting at the U.S. Department of Energy GE-Prolec CCE Meeting October 19,2010

  7. MEMORANDUM To: DOE Office of General Counsel From: Tony Bacon

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    MEMORANDUM To: DOE Office of General Counsel From: Tony Bacon Date: August 6, 2015 Re: Ex Parte Communication Memo This memo provides a summary of the communications made to the DOE staff regarding proposed rules on ceiling fan test procedures as well as proposed energy efficiency rules for ceiling fan light kits. The communications occurred during a teleconference on July 30, 2015. The meeting attendees included: Lucy Debutts (DOE) Ashley Armstrong (DOE) David Turner (Hunter Fan Company) Tony

  8. MEMORANDUM To: DOE Office of General Counsel From: Tony Bacon

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    To: DOE Office of General Counsel From: Tony Bacon Date: June 15, 2016 Re: Ex Parte Communication Memo This memo provides a summary of the communications made to the DOE staff regarding proposed rules on ceiling fan test procedures. The communications occurred during a teleconference on June 7, 2016. The meeting attendees included: Lucy Debutts (DOE) Ashley Armstrong (DOE) Bill Walker (Hunter Fan Company) Tony Bacon (Hunter Fan Company) Phil Daniels (Degree Controls, the company which supplies

  9. Appliance Standards Update and Review of Certification, Compliance and Enforcement Powerpoint Presentation for ASHRAE Conference, January 31, 2011

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Buildings Regulatory Program Buildings Regulatory Program Appliance Standards Update and Review of Certification, Compliance and Enforcement John Cymbalsky, Ashley Armstrong, and Laura Barhydt US Department of Energy January 31, 2011 Presentation Outline Presentation Outline * Upcoming Relevant Rulemakings * Changes to Rulemaking Process * Executive Order 13563 * Overview of Compliance, Certification, and Enforcement * Detailed Questions and Answers 2 | U.S. Department of Energy energy.gov Long

  10. DOE Meeting Memorandum: Ex Parte Communications

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    June 4, 2013 DOE Attendees: Ashley Armstrong, Lucy DeButts, and John Cymbalsky, EERE Building Technologies Program; Eric Haas, General Counsel Outside attendees: Patrick Keal, Big Ass Fans; Janie Wise, Vern Simmons, & Terry Paul, Cassidy & Associates Meeting Contact: Janie Wise - jwise@cassidy.com / 202-585-2553 Subject: Pending rulemakings on (1) Commercial and industrial fans and (2) Residential fans and lighting kits. Summary: Big Ass Fans is headquartered in Lexington, Kentucky, and

  11. DOE Meeting Memorandum: Ex Parte Communications

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    September 17, 2014 DOE Attendees: Ashley Armstrong, EERE Outside attendees: Bob Sullivan, Ormat Technologies and Janie Wise, Cassidy & Associates Meeting Contact: Janie Wise - jwise@cassidy.com / 202-585-2553 Subject: Request for Information on Efficiency Standards for Natural Gas Compressors Summary: Ormat Technologies is headquartered in Reno Nevada and designs and manufactures waste heat recovery units that are commonly applied on natural gas pipeline compressor stations. Ormat met with

  12. On October 20, 2011, representatives of Howe Corporation, Gade Environmental, an

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    October 20, 2011, representatives of Howe Corporation, Gade Environmental, and Beecon ProfServe met with DOE to discuss the proposed rules EERE-2010 BT-TP-0036 RIN 1904-AC38 Energy Efficiency Program for Certain Commercial and Industrial Equipment: Test Procedures for Commercial Ice Makers. The meeting was held at the request of Howe Corporation at the DOE offices in Washington DC. In attendance: Ari Altman, DOE Ashley Armstrong, DOE Robert Bittner, Beecon ProfServe John Cymbalsky, DOE Mary

  13. ICP-MS Data Analysis Software

    Energy Science and Technology Software Center (OSTI)

    1999-01-14

    VG2Xl - this program reads binary data files generated by VG instrumentals inductively coupled plasma-mass spectrometers using PlasmaQuad Software Version 4.2.1 and 4.2.2 running under IBM OS/2. ICPCalc - this module is a macro for Microsoft Excel written in VBA (Virtual Basic for Applications) that performs data analysis for ICP-MS data required for nuclear materials that cannot readily be done with the vendor''s software. VG2GRAMS - This program reads binary data files generated by VGmore » instruments inductively coupled plasma mass spectrometers using PlasmaQuad software versions 4.2.1 and 4.2.2 running under IBM OS/2.« less

  14. Municipal Energy Agency of MS | Open Energy Information

    Open Energy Info (EERE)

    Name: Municipal Energy Agency of MS Place: Mississippi Phone Number: (601) 362-2252 Facebook: https:www.facebook.compagesMunicipal-Energy-Agency-of-Mississippi Outage...

  15. Ms. Julie A. Smith Mr. Christopher Lawrence Office of Electricity...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    October 30, 2013 Ms. Julie A. Smith Mr. Christopher Lawrence Office of Electricity ... Smith and Mr. Lawrence: The Association of Fish and Wildlife Agencies (AFWA) would like to ...

  16. This is a paper model of the MS2 virus

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Researchers hope that MS2 therapies will help them around this problem. One cause of diabetes is an auto-immune reaction in which a person's immune system attacks the islet cells...

  17. Ms. Kimberly Krizanovic U.S. Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    0, 2012 Ms. Kimberly Krizanovic U.S. Department of Energy Office of the Chief Financial Officer 4 th Floor, Suite 4A-236 1000 Independence Avenue Washington, DC 20585 Dear Ms. Krizanovic: The American Institute of Certified Public Accountants (AICPA) is the national, professional association of CPAs, with 369,000 CPA members worldwide in business and industry, public practice, government, education, student affiliates and international associates. It sets ethical standards for the profession and

  18. Armstrong Teasdale Future Energy Group | Open Energy Information

    Open Energy Info (EERE)

    St. Louis, Missouri Zip: 63105 Sector: Bioenergy, Biofuels, Biomass, Buildings, Carbon, Efficiency, Geothermal energy, Hydro, Hydrogen, Renewable energy, Services, Solar,...

  19. Rock Sampling At Socorro Mountain Area (Armstrong, Et Al., 1995...

    Open Energy Info (EERE)

    SEM studies, and John Repetski (USGS, Reston, Virgina) conodont stratigraphy and color and textural alteration as guides to the carbonate rocks' thermal history. The...

  20. Ms. Paula Call NEPA Document Manager US Department of Energy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Via electronic mail landconveyanceEA@rl.doe.gov October 19, 2012 Ms. Paula Call NEPA Document Manager US Department of Energy Richland Operations Office P0 Box 550, MSIN A2-15 Richland, WA 99352 Re: Scoping Comments on the Department of Energy's Notice of Intent to Prepare an Environmental Assessment (EA) for the Proposed Conveyance of Land at the Hanford Site, Richland, WA and Notice of Potential Floodplain and Wetland Involvement. Dear Ms. Call, I am writing on behalf of Hanford Challenge to

  1. When worlds collide - Mac to MS-DOS. [Data transfer to and from Apple Macintosh computers and MS-DOS based personal computers

    SciTech Connect (OSTI)

    Busbey, A.B.

    1989-04-01

    A number of methods and products, both hardware and software, to allow data exchange between Apple Macintosh computers and MS-DOS based systems. These included serial null modem connections, MS-DOS hardware and/or software emulation, MS-DOS disk-reading hardware and networking.

  2. Method for factor analysis of GC/MS data

    DOE Patents [OSTI]

    Van Benthem, Mark H; Kotula, Paul G; Keenan, Michael R

    2012-09-11

    The method of the present invention provides a fast, robust, and automated multivariate statistical analysis of gas chromatography/mass spectroscopy (GC/MS) data sets. The method can involve systematic elimination of undesired, saturated peak masses to yield data that follow a linear, additive model. The cleaned data can then be subjected to a combination of PCA and orthogonal factor rotation followed by refinement with MCR-ALS to yield highly interpretable results.

  3. PNM Resources 2401 Aztec NE, MS-Z100

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    PNM Resources 2401 Aztec NE, MS-Z100 Albuquerque, NM 87107 505-241-2025 Fax 505 241-2384 PNMResources.com October 29, 2013 Mr. Christopher Lawrence Office of Electricity Delivery and Energy Reliability (OE-20) U.S. Department of Energy 1000 Independence Avenue, SW Washington, DC 20585 Submitted electronically via email to: Christopher.Lawrence@hq.doe.gov Dear Mr. Lawrence: Subject: Department of Energy (DOE)- Improving Performance of Federal Permitting and Review of Infrastructure Projects,

  4. ST. LCUIS ST. LallS JOKIN KFms Clrv S!. LrMS ST. Lcm

    Office of Legacy Management (LM)

    Ho. 30 !2121/87 smt6w cm ST. LCUIS ST. LallS JOKIN KFms Clrv S!. LrMS ST. Lcm

  5. Characterization of Fatty Acids in Crenarchaeota by GC-MS and...

    Office of Scientific and Technical Information (OSTI)

    Title: Characterization of Fatty Acids in Crenarchaeota by GC-MS and NMR Lipids composed ... Because lipids are energy currency and cell signaling molecules, their presence in Archaea ...

  6. PIK M.S. Onegin Petersburg Nuclear Physics Institute 2015 Super...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    isotopes production in high-flux reactor PIK M.S. Onegin Petersburg Nuclear Physics Institute 2015 Super Heavy Elements Symposium Reactor PIK 2011 - Criticality reached 2013 - ...

  7. ICP MS selection of radiopure materials for the GERDA experiment

    SciTech Connect (OSTI)

    Di Vacri, M. L.; Nisi, S.; Cattadori, C.; Janicsko, J.; Lubashevskiy, A.; Smolnikov, A.; Walter, M.

    2015-08-17

    The GERDA (GERmanium Detector Array) experiment, located in the Gran Sasso Underground Laboratory (LNGS, Italy) aims to search for neutrinoless double beta (0νββ) decay of the {sup 76}Ge isotope. Both an ultra-low radioactivity background environment and active techniques to abate the residual background are required to reach the background index (of 10{sup −3} counts/keV kg y) at the Q{sub ββ}. In order to veto and suppress those events that partially deposit energy in Ge detectors, the readout of liquid argon (LAr) scintillation light (SL) has been implemented for the second GERDA experimental Phase. A double veto system has been designed and constructed using highly radiopure materials (scintillating fibers, wavelength shifters, polymeric foils, reflective foils). This work describes the study of lead, thorium and uranium ultra-trace content, performed at the LNGS Chemistry Laboratory by High Resolution Mass Spectrometry (HR ICP MS), for the selection of all materials involved in the construction of the veto system.

  8. Gas chromatograph-mass spectrometer (GC/MS) system for quantitative analysis of reactive chemical compounds

    DOE Patents [OSTI]

    Grindstaff, Quirinus G.

    1992-01-01

    Described is a new gas chromatograph-mass spectrometer (GC/MS) system and method for quantitative analysis of reactive chemical compounds. All components of such a GC/MS system external to the oven of the gas chromatograph are programmably temperature controlled to operate at a volatilization temperature specific to the compound(s) sought to be separated and measured.

  9. On the Ionization and Ion Transmission Efficiencies of Different ESI-MS Interfaces

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Cox, Jonathan T.; Marginean, Ioan; Smith, Richard D.; Tang, Keqi

    2014-09-30

    It is well known that the achievable sensitivity of electrospray ionization mass spectrometry (ESI-MS) is largely determined by the ionization efficiency in the ESI source and ion transmission efficiency through the ESI-MS interface. In this report we systematically study the ion transmission and ionization efficiencies in different ESI-MS interface configurations. The configurations under investigation include a single emitter/single inlet capillary, single emitter/multi-inlet capillary, and a subambient pressure ionization with nanoelectrospray (SPIN) MS interfaces with a single emitter and an emitter array, respectively. We present an effective method to evaluate the overall ion utilization efficiency of an ESI-MS interface by measuringmore » the total gas phase ion current transmitted through the interface and correlating it to the observed ion abundance measured in the corresponding mass spectrum. Our experimental results suggest that the overall ion utilization efficiency in the SPIN-MS interface configurations is better than that in the inlet capillary based ESI-MS interface configurations.« less

  10. On the Ionization and Ion Transmission Efficiencies of Different ESI-MS Interfaces

    SciTech Connect (OSTI)

    Cox, Jonathan T.; Marginean, Ioan; Smith, Richard D.; Tang, Keqi

    2014-09-30

    It is well known that the achievable sensitivity of electrospray ionization mass spectrometry (ESI-MS) is largely determined by the ionization efficiency in the ESI source and ion transmission efficiency through the ESI-MS interface. In this report we systematically study the ion transmission and ionization efficiencies in different ESI-MS interface configurations. The configurations under investigation include a single emitter/single inlet capillary, single emitter/multi-inlet capillary, and a subambient pressure ionization with nanoelectrospray (SPIN) MS interfaces with a single emitter and an emitter array, respectively. We present an effective method to evaluate the overall ion utilization efficiency of an ESI-MS interface by measuring the total gas phase ion current transmitted through the interface and correlating it to the observed ion abundance measured in the corresponding mass spectrum. Our experimental results suggest that the overall ion utilization efficiency in the SPIN-MS interface configurations is better than that in the inlet capillary based ESI-MS interface configurations.

  11. Training is sponsoring two MS PowerPoint Courses. The course...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Training is sponsoring two MS PowerPoint Courses. The course options feature level 1 and level 2. This email is to gauge interest. The associated cost per class is 200.00. If...

  12. Paul W. King, Ph.D., M.S. | Bioenergy | NREL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Paul W. King Paul W. King, Ph.D., M.S. Scientist VI - Supervisor, Photobiology Group Paul.King@nrel.gov | 303-384-6277 Research Interests Paul King's research interests are broadly ...

  13. File:USDA-CE-Production-GIFmaps-MS.pdf | Open Energy Information

    Open Energy Info (EERE)

    MS.pdf Jump to: navigation, search File File history File usage Mississippi Ethanol Plant Locations Size of this preview: 776 600 pixels. Full resolution (1,650 1,275...

  14. Ms. Brenda Edwards U.S. Department of Energy, Buildings Technology Program

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    8, 2013 Ms. Brenda Edwards U.S. Department of Energy, Buildings Technology Program Mail Stop EE-2J 1000 Independence Ave. SW Washington DC 20585-0121 RE: Revisions to Energy Efficiency Enforcement Regulations EERE-2011-BT-TD- 0005 Dear Ms. Edwards: The National Marine Manufacturers Association (NMMA) appreciates the opportunity to respond to the Department of Energy (DOE), Office of Energy Efficiency and Renewable Energy's request for information published in the Federal Register (78 Fed. Reg.

  15. DOE - Office of Legacy Management -- Tatum Salt Dome Test Site - MS 01

    Office of Legacy Management (LM)

    Tatum Salt Dome Test Site - MS 01 Site ID (CSD Index Number): MS.01 Site Name: Tatum Salt Dome Test Site Site Summary: Site Link: http://www.lm.doe.gov/salmon/Sites.aspx External Site Link: Alternate Name(s): Tatum Salt Dome Test Site Alternate Name Documents: Location: Salmon, Mississippi Location Documents: Historical Operations (describe contaminants): Underground nuclear test site Historical Operations Documents: Eligibility Determination: Remediated by DOE Eligibility Determination

  16. Modeling and simulation of Red Teaming. Part 1, Why Red Team M&S?

    SciTech Connect (OSTI)

    Skroch, Michael J.

    2009-11-01

    Red teams that address complex systems have rarely taken advantage of Modeling and Simulation (M&S) in a way that reproduces most or all of a red-blue team exchange within a computer. Chess programs, starting with IBM's Deep Blue, outperform humans in that red-blue interaction, so why shouldn't we think computers can outperform traditional red teams now or in the future? This and future position papers will explore possible ways to use M&S to augment or replace traditional red teams in some situations, the features Red Team M&S should possess, how one might connect live and simulated red teams, and existing tools in this domain.

  17. Ms. Chris Andres, Chief Bureau of Federal Facilities Division of Environmental Protection

    Office of Legacy Management (LM)

    Ms. Chris Andres, Chief Bureau of Federal Facilities Division of Environmental Protection 2030 E. Flamingo Road, Suite 230 Las Vegas, NV 89119-0818 June 16,2014 PATH FORWARD: 2014 SHORT-TERM DATA ACQUISITION PLAN PROJECT SHOAL AREA, SUB SURF ACE CORRECTIVE ACTION UNIT 44 7, NEVADA Dear Ms. Andres: The U.S. Departtnent of Energy (DOE) Office of Legacy Management (LM) is providing this Short- Term Data Acquisition Plan for the Shoal, Nevada, Site, Subsurface Corrective Action Unit 447, near

  18. Improving Alpha Spectrometry Energy Resolution by Ion Implantation with ICP-MS

    SciTech Connect (OSTI)

    Dion, Michael P.; Liezers, Martin; Farmer, Orville T.; Miller, Brian W.; Morley, Shannon M.; Barinaga, Charles J.; Eiden, Gregory C.

    2015-01-01

    We report results of a novel technique using an Inductively Coupled Plasma Mass Spectrometer (ICP-MS) as a method of source preparation for alpha spectrometry. This method produced thin, contaminant free 241Am samples which yielded extraordinary energy resolution which appear to be at the lower limit of the detection technology used in this research.

  19. Dear Ms

    Office of Environmental Management (EM)

    31, 2012 Office of the General Counsel, Department of Energy Dear Mr. Cohen, Unfortunately we missed the dead line for the first set of comments regarding regulatory burden. We've searched the web at http://www.regulations.gov for any comments from the first round due on January 5, 2012 and could not find any. The situation we described last year (see below) has not improved. We are waiting for additional rules from DOE but don't believe they'll provide the needed relief from regulatory burden.

  20. Dear Ms

    Office of Environmental Management (EM)

    oral, as well as written. The main purpose of these discussions is to notify [insert name of offeror] of deficiencies and weaknesses in its proposal, as well as other aspects of its proposal that could be altered or explained. These deficiencies, weaknesses and other aspects of the proposal that could be altered or explained are specified in Attachment 1. [insert name of offeror] is requested to meet with the DOE SEB on [insert date] , beginning at [insert time] in [insert location] to discuss

  1. Dear Ms

    Office of Environmental Management (EM)

    in writing. The main purpose of these discussions is to notify [insert name of offeror] of deficiencies and weaknesses in its proposal, as well as other aspects of its proposal that could be altered or explained. These deficiencies, weaknesses and other aspects of the proposal that could be altered or explained are specified in Attachment 1. [insert name of offeror] should address each issue identified in Attachment 1 thoroughly in a written response to DOE. Your response is required no later

  2. An enhanced droplet-based liquid microjunction surface sampling system coupled with HPLC-ESI-MS/MS for spatially resolved analysis

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Van Berkel, Gary J.; Weiskittel, Taylor M.; Kertesz, Vilmos

    2014-11-07

    Droplet-based liquid microjunction surface sampling coupled with high-performance liquid chromatography (HPLC)-electrospray ionization (ESI)-tandem mass spectrometry (MS/MS) for spatially resolved analysis provides the possibility of effective analysis of complex matrix samples and can provide a greater degree of chemical information from a single spot sample than is typically possible with a direct analysis of an extract. Described here is the setup and enhanced capabilities of a discrete droplet liquid microjunction surface sampling system employing a commercially available CTC PAL autosampler. The system enhancements include incorporation of a laser distance sensor enabling unattended analysis of samples and sample locations of dramatically disparatemore » height as well as reliably dispensing just 0.5 μL of extraction solvent to make the liquid junction to the surface, wherein the extraction spot size was confined to an area about 0.7 mm in diameter; software modifications improving the spatial resolution of sampling spot selection from 1.0 to 0.1 mm; use of an open bed tray system to accommodate samples as large as whole-body rat thin tissue sections; and custom sample/solvent holders that shorten sampling time to approximately 1 min per sample. Lastly, the merit of these new features was demonstrated by spatially resolved sampling, HPLC separation, and mass spectral detection of pharmaceuticals and metabolites from whole-body rat thin tissue sections and razor blade (“crude”) cut mouse tissue.« less

  3. Response Model for Kodak Biomax-MS Film to X Rays

    SciTech Connect (OSTI)

    Knauer, J.P.; Marshall, F.J.; Yaakobi, B.; Anderson, D.; Schmitt, B.A.; Chandler, K.M.; Pikuz, S.A.; Shelkovenko, T.A.; Mitchell, M.D.; Hammer, D.A.

    2007-01-24

    X-raysensitive film is used for a variety of imaging and spectroscopic diagnostics for high-temperature plasmas. New film becomes available as older films are phased out of production. Biomax-MS is a T-grain class of film that is proposed as a replacement for Kodak DEF film. A model of its response to x rays is presented. Data from dimensional measurements of the film, x-ray transmission measurements, SEM micrograph images, and x-ray calibration are used to develop this sensitivity model of Biomax-MS film as a function of x-ray energy and angle of incidence. Relative response data provide a check of the applicability of this model to determine the x-ray flux from spectrum data. This detailed film characterization starts with simple mathematical models and extends them to T-grain type film.

  4. Response model for Kodak Biomax-MS film to x rays

    SciTech Connect (OSTI)

    Knauer, J. P.; Marshall, F. J.; Yaakobi, B.; Anderson, D.; Schmitt, B. A.; Chandler, K. M.; Pikuz, S. A.; Shelkovenko, T. A.; Mitchell, M. D.; Hammer, D. A.

    2006-10-15

    X-ray-sensitive film is used for a variety of imaging and spectroscopic diagnostics for high-temperature plasmas. Replacement film must be found as older films are phased out of production. Biomax-MS is a 'T-grain' class of film that is proposed as a replacement for Kodak DEF and a model of its response to x rays is presented. Data from dimensional measurements of the film, x-ray transmission measurements, scanning electron microscopy micrograph images, and x-ray calibration are used to develop this sensitivity model of Biomax-MS film as a function of x-ray energy and angle of incidence. Relative response data provide a check of the applicability of this model to determine the x-ray flux from spectrum data. This detailed film characterization starts with simple mathematical models and extends them to T-grain-type film.

  5. To: Ms. Brenda Edwards U.S. Department of Energy, Building Technologies Program

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    0, 2012 To: Ms. Brenda Edwards U.S. Department of Energy, Building Technologies Program Mailstop EE-2J, 1000 Independence Avenue Washington, DC 20585-0121 Phone: (202) 586-2945 cc: Michelle Blaise (VP, ComEd Engineering & Project Management) Joseph Watson (Director, Federal Government Affairs) Martin Rave (Prin Engineer, ComEd Distribution Standards) From: Peter Tyschenko (Manager, ComEd Distribution Standards) Two Lincoln Centre Oakbrook Terrace, IL 60181-4260 Phone: (630) 576-6998 Subject:

  6. To: Ms. Brenda Edwards U.S. Department of Energy, Building Technologies Program

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    8, 2011 To: Ms. Brenda Edwards U.S. Department of Energy, Building Technologies Program Mailstop EE-2J, 1000 Independence Avenue Washington, DC 20585-0121 Phone: (202) 586-2945 cc: Michelle Blaise (VP, ComEd Engineering & Project Management) Joseph Watson (Director, Federal Government Affairs) Martin Rave (Prin Engineer, ComEd Distribution Standards) From: Peter Tyschenko (Manager, ComEd Distribution Standards) Two Lincoln Centre Oakbrook Terrace, IL 60181-4260 Phone: (630) 576-6998 Subject:

  7. Ms Van T Nguyen | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Van T Nguyen Scientific User Facilities (SUF) Division SUF Home About Staff Dr. James B. Murphy What's New User Facilities Projects Accelerator & Detector Research Science Highlights Principal Investigators' Meetings BES Home Staff Ms. Van T Nguyen Print Text Size: A A A FeedbackShare Page Van T. Nguyen Program Manager Facility Coordination, Metrics, and Assessment Office of Basic Energy Sciences SC-22.3/Germantown Building U.S. Department of Energy 1000 Independence Avenue, SW Washington,

  8. Sources of Technical Variability in Quantitative LC-MS Proteomics: Human Brain Tissue Sample Analysis.

    SciTech Connect (OSTI)

    Piehowski, Paul D.; Petyuk, Vladislav A.; Orton, Daniel J.; Xie, Fang; Moore, Ronald J.; Ramirez Restrepo, Manuel; Engel, Anzhelika; Lieberman, Andrew P.; Albin, Roger L.; Camp, David G.; Smith, Richard D.; Myers, Amanda J.

    2013-05-03

    To design a robust quantitative proteomics study, an understanding of both the inherent heterogeneity of the biological samples being studied as well as the technical variability of the proteomics methods and platform is needed. Additionally, accurately identifying the technical steps associated with the largest variability would provide valuable information for the improvement and design of future processing pipelines. We present an experimental strategy that allows for a detailed examination of the variability of the quantitative LC-MS proteomics measurements. By replicating analyses at different stages of processing, various technical components can be estimated and their individual contribution to technical variability can be dissected. This design can be easily adapted to other quantitative proteomics pipelines. Herein, we applied this methodology to our label-free workflow for the processing of human brain tissue. For this application, the pipeline was divided into four critical components: Tissue dissection and homogenization (extraction), protein denaturation followed by trypsin digestion and SPE clean-up (digestion), short-term run-to-run instrumental response fluctuation (instrumental variance), and long-term drift of the quantitative response of the LC-MS/MS platform over the 2 week period of continuous analysis (instrumental stability). From this analysis, we found the following contributions to variability: extraction (72%) >> instrumental variance (16%) > instrumental stability (8.4%) > digestion (3.1%). Furthermore, the stability of the platform and its suitability for discovery proteomics studies is demonstrated.

  9. Evaluation of ultra-low background materials for uranium and thorium using ICP-MS

    SciTech Connect (OSTI)

    Hoppe, E. W.; Overman, N. R.; LaFerriere, B. D.

    2013-08-08

    An increasing number of physics experiments require low background materials for their construction. The presence of Uranium and Thorium and their progeny in these materials present a variety of unwanted background sources for these experiments. The sensitivity of the experiments continues to drive the necessary levels of detection ever lower as well. This requirement for greater sensitivity has rendered direct radioassay impractical in many cases requiring large quantities of material, frequently many kilograms, and prolonged counting times, often months. Other assay techniques have been employed such as Neutron Activation Analysis but this requires access to expensive facilities and instrumentation and can be further complicated and delayed by the formation of unwanted radionuclides. Inductively Coupled Plasma Mass Spectrometry (ICP-MS) is a useful tool and recent advancements have increased the sensitivity particularly in the elemental high mass range of U and Th. Unlike direct radioassay, ICP-MS is a destructive technique since it requires the sample to be in liquid form which is aspirated into a high temperature plasma. But it benefits in that it usually requires a very small sample, typically about a gram. This paper discusses how a variety of low background materials such as copper, polymers, and fused silica are made amenable to ICP-MS assay and how the arduous task of maintaining low backgrounds of U and Th is achieved.

  10. Evaluation of Ultra-Low Background Materials for Uranium and Thorium Using ICP-MS

    SciTech Connect (OSTI)

    Hoppe, Eric W.; Overman, Nicole R.; LaFerriere, Brian D.

    2013-08-08

    An increasing number of physics experiments require low background materials for their construction. The presence of Uranium and Thorium and their progeny in these materials present a variety of unwanted background sources for these experiments. The sensitivity of the experiments continues to drive the necessary levels of detection ever lower as well. This requirement for greater sensitivity has rendered direct radioassay impractical in many cases requiring large quantities of material, frequently many kilograms, and prolonged counting times, often months. Other assay techniques have been employed such as Neutron Activation Analysis but this requires access to expensive facilities and instrumentation and can be further complicated and delayed by the formation of unwanted radionuclides. Inductively Coupled Plasma Mass Spectrometry (ICP-MS) is a useful tool and recent advancements have increased the sensitivity particularly in the elemental high mass range of U and Th. Unlike direct radioassay, ICP-MS is a destructive technique since it requires the sample to be in liquid form which is aspirated into a high temperature plasma. But it benefits in that it usually requires a very small sample, typically about a gram. Here we will discuss how a variety of low background materials such as copper, polymers, and fused silica are made amenable to ICP-MS assay and how the arduous task of maintaining low backgrounds of U and Th is achieved.

  11. Ion mobility spectrometry–mass spectrometry (IMS–MS) for on- and offline analysis of atmospheric gas and aerosol species

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Krechmer, Jordan E.; Groessl, Michael; Zhang, Xuan; Junninen, Heikki; Massoli, Paola; Lambe, Andrew T.; Kimmel, Joel R.; Cubison, Michael J.; Graf, Stephan; Lin, Ying-Hsuan; et al

    2016-07-25

    Measurement techniques that provide molecular-level information are needed to elucidate the multiphase processes that produce secondary organic aerosol (SOA) species in the atmosphere. Here we demonstrate the application of ion mobility spectrometry-mass spectrometry (IMS–MS) to the simultaneous characterization of the elemental composition and molecular structures of organic species in the gas and particulate phases. Molecular ions of gas-phase organic species are measured online with IMS–MS after ionization with a custom-built nitrate chemical ionization (CI) source. This CI–IMS–MS technique is used to obtain time-resolved measurements (5 min) of highly oxidized organic molecules during the 2013 Southern Oxidant and Aerosol Study (SOAS) ambientmore » field campaign in the forested SE US. The ambient IMS–MS signals are consistent with laboratory IMS–MS spectra obtained from single-component carboxylic acids and multicomponent mixtures of isoprene and monoterpene oxidation products. Mass-mobility correlations in the 2-D IMS–MS space provide a means of identifying ions with similar molecular structures within complex mass spectra and are used to separate and identify monoterpene oxidation products in the ambient data that are produced from different chemical pathways. Water-soluble organic carbon (WSOC) constituents of fine aerosol particles that are not resolvable with standard analytical separation methods, such as liquid chromatography (LC), are shown to be separable with IMS–MS coupled to an electrospray ionization (ESI) source. The capability to use ion mobility to differentiate between isomers is demonstrated for organosulfates derived from the reactive uptake of isomers of isoprene epoxydiols (IEPOX) onto wet acidic sulfate aerosol. Controlled fragmentation of precursor ions by collisionally induced dissociation (CID) in the transfer region between the IMS and the MS is used to validate MS peak assignments, elucidate structures of

  12. Toward Joint Hypothesis-Tests Seismic Event Screening Analysis: Ms|mb and Event Depth

    SciTech Connect (OSTI)

    Anderson, Dale; Selby, Neil

    2012-08-14

    Well established theory can be used to combine single-phenomenology hypothesis tests into a multi-phenomenology event screening hypothesis test (Fisher's and Tippett's tests). Commonly used standard error in Ms:mb event screening hypothesis test is not fully consistent with physical basis. Improved standard error - Better agreement with physical basis, and correctly partitions error to include Model Error as a component of variance, correctly reduces station noise variance through network averaging. For 2009 DPRK test - Commonly used standard error 'rejects' H0 even with better scaling slope ({beta} = 1, Selby et al.), improved standard error 'fails to rejects' H0.

  13. WILLIAM C. LOUIS Los Alamos National Laboratory M.S. H846 Los

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    WILLIAM C. LOUIS Los Alamos National Laboratory M.S. H846 Los Alamos, NM 87545 louis@lanl.gov, 505/667-6723 EMPLOYMENT Technical Staff Member, Los Alamos National Laboratory, P-Division, 1987-present Assistant Professor, Princeton University, 1981-1987 Research Associate, Rutherford Laboratory, 1978-1981 POSITIONS LANL Program Manager for Nuclear Physics, 2004-2009 Co-Spokesperson of the BooNE Neutrino Experiment at Fermilab, 1998-2007 Spokesperson of the LSND Neutrino Experiment at Los Alamos,

  14. ATOMIC ENERGY CO&lbiISSION ms AlAMos. NEW MMICO

    Office of Legacy Management (LM)

    ATOMIC ENERGY CO&lbiISSION ms AlAMos. NEW MMICO 87544 JUL 5 1973 H. C. Donnelly, Manager Albuquerque Operations UNNEEDED REAL PROPERTY - LOS AL-4MOS AREA OFFICE In our annual review of real property holdings at the Los Alamos Area Office we have identified four individual tracts within the community which are unneeded. An envi~konmental radioactivity survey has been conducted on each of the areas and no radiation or radiocontamination observations were encountered which are of radiological

  15. Market Research Survey of Commercial Off-The-Shelf (COTS) Portable MS Systems for IAEA Safeguards Applications

    SciTech Connect (OSTI)

    Hart, Garret L.; Hager, George J.; Barinaga, Charles J.; Duckworth, Douglas C.

    2013-02-01

    This report summarizes the results for the market research survey of mass spectrometers that are deemed pertinent to International Atomic Energy Agency (IAEA) needs and strategic objectives. The focus of the report is on MS instruments that represent currently available (or soon to be) commercial off-the shelf (COTS) technology and weigh less than 400 pounds. A compilation of all available MS instruments (36 COTS and 2 R&D) is presented, along with pertinent information regarding each instrument.

  16. Issues Pertaining to the Termination of Ms. Donna Busche, a Contractor Employee at the Waste Treatment Plant Project

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    REVIEW Issues Pertaining to the Termination of Ms. Donna Busche, a Contractor Employee at the Waste Treatment Plant Project DOE/IG-0923 October 2014 U.S. Department of Energy Office of Inspector General Office of Audits and Inspections Department of Energy Washington, DC 20585 October 17, 2014 MEMORANDUM FOR THE SECRETARY FROM: Gregory H. Friedman Inspector General SUBJECT: Special Review of "Issues Pertaining to the Termination of Ms. Donna Busche, a Contractor Employee at the Waste

  17. Recent advances in the speciation of selenium in petroleum refinery and municipal waste using ICP-MS and ICP-MS coupled with liquid chromatography

    SciTech Connect (OSTI)

    Roehl, R.

    1996-09-01

    An analytical scheme for the speciation of selenium in petroleum refinery waste waters reported at the 1994 Winter Plasma Conference included methods for the determination of total, dissolved, particulate and volatile selenium, as well as for the separate quantitation of dissolved selenite, selenate and selenocyanate. Several of those methods have been improved significantly. Determinations of total, dissolved, and particulate selenium are based on the ICP-MS quantitation of the {sup 82}Se isotope in waste water samples or sample fractions digested with hydrogen peroxide and nitric acid. These analyses now include corrections for potential isobaric interferences are minimized by monitoring the signals for Br{sup +} and m/z 79 and SO{sub 3}H{sup +} at m/z 83 and correcting the apparent {sup 82}Se{sup +} signal using appropriate equations with correction factors derived from the analysis of calibration solutions containing sulfate and bromide. The correction factors used in those equations relate ionic species of different composition to each other (e.g., Br{sup +} and HBr{sup +}). To help ensure that the relative rate of formation of those ions in the plasma is not sample dependent, high concentrations of sodium and other easily ionized elements are removed from the sample digests by cation-exchange.

  18. Characterization of CMPO and its radiolysis products by Direct Infusion ESI-MS

    SciTech Connect (OSTI)

    G. S. Groenewold; G. Elias; B. J. Mincher; S. P. Mezyk

    2012-09-01

    Direct infusion electrospray ionization-mass spectrometry (ESI-MS) approaches were developed for rapid identification of octyl,phenyl,(N,N-(diisobutyl)carbamoylmethyl) phosphine oxide (CMPO) and impurity compounds formed during alpha and gamma irradiation experiments. CMPO is an aggressive Lewis base, and produces extremely abundant metal complex ions in the ESI-MS analysis that make identification of low abundance compounds that are less nucleophilic challenging. Radiolysis products were identified using several approaches including restricting ion trapping so as to exclude the abundant natiated CMPO ions, extraction of acidic products using aqueous NaOH, and extraction of basic products using HNO3. These approaches generated protonated, natiated and deprotonated species derived from CMPO degradation products formed via radiolytic cleavages of several different bonds. Cleavages of the amide and methylene-phosphoryl bonds appear to be favored by both forms of irradiation, while alpha irradiation also appears to induce cleavage of the methylene-carbonyl bond. The degradation products observed are formed from recombination of the initially formed radicals with hydrogen, methyl, isopropyl and hydroxyl radicals that are derived either from CMPO, or the dodecane solvent.

  19. Reduction of Solvent Effect in Reverse Phase Gradient Elution LC-ICP-MS

    SciTech Connect (OSTI)

    Patrick Allen Sullivan

    2005-12-17

    Quantification in liquid chromatography (LC) is becoming very important as more researchers are using LC, not as an analytical tool itself, but as a sample introduction system for other analytical instruments. The ability of LC instrumentation to quickly separate a wide variety of compounds makes it ideal for analysis of complex mixtures. For elemental speciation, LC is joined with inductively coupled plasma mass spectrometry (ICP-MS) to separate and detect metal-containing, organic compounds in complex mixtures, such as biological samples. Often, the solvent gradients required to perform complex separations will cause matrix effects within the plasma. This limits the sensitivity of the ICP-MS and the quantification methods available for use in such analyses. Traditionally, isotope dilution has been the method of choice for LC-ICP-MS quantification. The use of naturally abundant isotopes of a single element in quantification corrects for most of the effects that LC solvent gradients produce within the plasma. However, not all elements of interest in speciation studies have multiple naturally occurring isotopes; and polyatomic interferences for a given isotope can develop within the plasma, depending on the solvent matrix. This is the case for reverse phase LC separations, where increasing amounts of organic solvent are required. For such separations, an alternative to isotope dilution for quantification would be is needed. To this end, a new method was developed using the Apex-Q desolvation system (ESI, Omaha, NE) to couple LC instrumentation with an ICP-MS device. The desolvation power of the system allowed greater concentrations of methanol to be introduced to the plasma prior to destabilization than with direct methanol injection into the plasma. Studies were performed, using simulated and actual linear methanol gradients, to find analyte-internal standard (AIS) pairs whose ratio remains consistent (deviations {+-} 10%) over methanol concentration ranges of 5

  20. Elemental speciation in biomolecules by LC-ICP-MS with magnetic sector and collision cell instruments

    SciTech Connect (OSTI)

    Wang, Jin

    1999-11-08

    A methodology that can monitor and identify inorganic elements in biological and environmental systems was developed. Size exclusion chromatography (SEC) separates biomolecules, which are then nebulized by a microconcentric nebulizer. The resulting aerosol is desolved and introduced into either a high resolution ICP-MS device or a quadrupole device with a collision cell. Because of the high sensitivity and spectral resolution and high sample introduction efficiency, many unusual or difficult elements, such as Cr, Se, Cd and U, can be observed at ambient levels bound to proteins in human serum. These measurements are made in only a few minutes without preliminary isolation and preconcentration steps. Serum samples can be titrated with spikes of various elements to determine which proteins bind a given metal and oxidation state. Experiments concerning the effects of breaking disulfide linkages and denaturation on metal binding in proteins were also investigated. Elemental distribution in liver extract was also obtained.

  1. Studies on the content of heavy metals in Aries River using ICP-MS

    SciTech Connect (OSTI)

    Voica, Cezara Kovacs, Melinda Feher, Ioana

    2013-11-13

    Among the industrial branches, the mining industry has always been an important source of environmental pollution, both aesthetically and chemically. Through this paper results of ICP-MS characterization of Aries River Basin are reported. Mining activities from this area has resulted in contamination of environment and its surrounding biota. This is clearly evidenced in analyzed water samples, especially from Baia de Aries site where increased amount of trace elements as Cr, Zn, As, Se, Cd, Pb and U were founded. Also in this site greater amount of rare earth elements was evidenced also. Through monitoring of Aries River from other non-mining area it was observed that the quantitative content of heavy metals was below the maximum permissible levels which made us to conclude that the water table wasn't seriously affected (which possibly might be attributed to the cessation of mining activities in this area from a few years ago)

  2. Pentaerythritol Tetranitrate (PETN) Surveillance by HPLC-MS: Instrumental Parameters Development

    SciTech Connect (OSTI)

    Harvey, C A; Meissner, R

    2005-11-04

    Surveillance of PETN Homologs in the stockpile here at LLNL is currently carried out by high performance liquid chromatography (HPLC) with ultra violet (UV) detection. Identification of unknown chromatographic peaks with this detection scheme is severely limited. The design agency is aware of the limitations of this methodology and ordered this study to develop instrumental parameters for the use of a currently owned mass spectrometer (MS) as the detection system. The resulting procedure would be a ''drop-in'' replacement for the current surveillance method (ERD04-524). The addition of quadrupole mass spectrometry provides qualitative identification of PETN and its homologs (Petrin, DiPEHN, TriPEON, and TetraPEDN) using a LLNL generated database, while providing mass clues to the identity of unknown chromatographic peaks.

  3. Mass Spectrometry Data from the Biological MS Data and Software Distribution Center

    DOE Data Explorer [Office of Scientific and Technical Information (OSTI)]

    Anderson, Gordon

    The mass spectrometry capabilities at Pacific Northwest National Laboratory (PNNL) are primarily applied to biological research, with an emphasis on proteomics and metabolomics. Many of these cutting-edge mass spectrometry capabilities and bioinformatics methods are housed in the Department of Energy's Environmental Molecular Sciences Laboratory (EMSL), a national scientific user facility operated by PNNL. These capabilities have been developed and acquired through cooperation between the EMSL national scientific user program and PNNL programmatic research. At the website of the Biological MS Data and Software Distribution Center, the following resources are made available: PNNL-developed software tools and source code, PNNL-generated raw data and processed results, links to publications that used the data and results available on this site, and tutorials and user manuals. [taken from http://omics.pnl.gov/

  4. Application of Printed Circuit Board Technology to FT-ICR MS Analyzer Cell Construction and Prototyping

    SciTech Connect (OSTI)

    Leach, Franklin E.; Norheim, Randolph V.; Anderson, Gordon A.; Pasa-Tolic, Ljiljana

    2014-12-01

    Although Fourier transform ion cyclotron resonance mass spectrometry (FT-ICRMS) remains themass spectrometry platform that provides the highest levels of performance for mass accuracy and resolving power, there is room for improvement in analyzer cell design as the ideal quadrupolar trapping potential has yet to be generated for a broadband MS experiment. To this end, analyzer cell designs have improved since the field’s inception, yet few research groups participate in this area because of the high cost of instrumentation efforts. As a step towards reducing this barrier to participation and allowing for more designs to be physically tested, we introduce a method of FT-ICR analyzer cell prototyping utilizing printed circuit boards at modest vacuum conditions. This method allows for inexpensive devices to be readily fabricated and tested over short intervals and should open the field to laboratories lacking or unable to access high performance machine shop facilities because of the required financial investment.

  5. Profiling of Adrenocorticotropic Hormone and Arginine Vasopressin in Human Pituitary Gland and Tumor Thin Tissue Sections using Droplet-Based Liquid Microjunction Surface Sampling-HPLC-ESI-MS/MS

    SciTech Connect (OSTI)

    Kertesz, Vilmos; Van Berkel, Gary J; Calligaris, David; Feldman, Daniel R; Changelian, Armen; Laws, Edward R; Santagata, Sandro; Agar, Nathalie YR

    2015-01-01

    Described here are the results from the profiling of the proteins arginine vasopressin (AVP) and adrenocorticotropic hormone (ACTH) from normal human pituitary gland and pituitary adenoma tissue sections using a fully automated droplet-based liquid microjunction surface sampling-HPLC-ESI-MS/MS system for spatially resolved sampling, HPLC separation, and mass spectral detection. Excellent correlation was found between the protein distribution data obtained with this droplet-based liquid microjunction surface sampling-HPLC-ESI-MS/MS system and those data obtained with matrix assisted laser desorption ionization (MALDI) chemical imaging analyses of serial sections of the same tissue. The protein distributions correlated with the visible anatomic pattern of the pituitary gland. AVP was most abundant in the posterior pituitary gland region (neurohypophysis) and ATCH was dominant in the anterior pituitary gland region (adenohypophysis). The relative amounts of AVP and ACTH sampled from a series of ACTH secreting and non-secreting pituitary adenomas correlated with histopathological evaluation. ACTH was readily detected at significantly higher levels in regions of ACTH secreting adenomas and in normal anterior adenohypophysis compared to non-secreting adenoma and neurohypophysis. AVP was mostly detected in normal neurohypophysis as anticipated. This work demonstrates that a fully automated droplet-based liquid microjunction surface sampling system coupled to HPLC-ESI-MS/MS can be readily used for spatially resolved sampling, separation, detection, and semi-quantitation of physiologically-relevant peptide and protein hormones, such as AVP and ACTH, directly from human tissue. In addition, the relative simplicity, rapidity and specificity of the current methodology support the potential of this basic technology with further advancement for assisting surgical decision-making.

  6. A comparison of the y-Radiolysis of TODGA and T(EH)DGA using UHPLC-ESI-MS analysis

    SciTech Connect (OSTI)

    Zarzana, Christopher A.; Groenewold, Gary S.; Mincher, Bruce J.; Mezyk, Stephen P.; Wilden, Andreas; Schmidt, Holger; Modolo, Giuseppe; Wishart, James F.; Cook, Andrew R.

    2015-04-27

    Solutions of the diglycolamide extractants TODGA and T(EH)DGA in n-dodecane were subjected to?- irradiation in the presence and absence of an acidic aqueous phase. These solutions were then analyzed using UHPLC-ESI-MS to determine the rates of radiolytic decay of the two extractants neat and in contact with respect to the acidity of the contacted aqueous phase, as well as to identify radiolysis products. The presence or absence of an acidic aqueous phase was shown to have no influence on the measured decay rates, nor did the side-chain have an influence. A number of radiolysis products were identified, consistent with those previously identified for these two compounds using GC-MS. The identity of these radiolysis products suggests that the bonds most vulnerable to radiolytic attack are those in the dyglycolamide center of these molecules, and not on the side-chains.The agreement of these results with previous work using GC-MS indicates supports the further use of UHPLC-ESI-MS as a tool for studying diglycolamide extractant systems.

  7. A comparison of the y-Radiolysis of TODGA and T(EH)DGA using UHPLC-ESI-MS analysis

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Zarzana, Christopher A.; Groenewold, Gary S.; Mincher, Bruce J.; Mezyk, Stephen P.; Wilden, Andreas; Schmidt, Holger; Modolo, Giuseppe; Wishart, James F.; Cook, Andrew R.

    2015-04-27

    Solutions of the diglycolamide extractants TODGA and T(EH)DGA in n-dodecane were subjected to γ- irradiation in the presence and absence of an acidic aqueous phase. These solutions were then analyzed using UHPLC-ESI-MS to determine the rates of radiolytic decay of the two extractants neat and in contact with respect to the acidity of the contacted aqueous phase, as well as to identify radiolysis products. The presence or absence of an acidic aqueous phase was shown to have no influence on the measured decay rates, nor did the side-chain have an influence. A number of radiolysis products were identified, consistent with thosemore » previously identified for these two compounds using GC-MS. The identity of these radiolysis products suggests that the bonds most vulnerable to radiolytic attack are those in the dyglycolamide center of these molecules, and not on the side-chains.  The agreement of these results with previous work using GC-MS indicates supports the further use of UHPLC-ESI-MS as a tool for studying diglycolamide extractant systems.« less

  8. A comparison of the y-Radiolysis of TODGA and T(EH)DGA using UHPLC-ESI-MS analysis

    SciTech Connect (OSTI)

    Zarzana, Christopher A.; Groenewold, Gary S.; Mincher, Bruce J.; Mezyk, Stephen P.; Wilden, Andreas; Schmidt, Holger; Modolo, Giuseppe; Wishart, James F.; Cook, Andrew R.

    2015-04-27

    Solutions of the diglycolamide extractants TODGA and T(EH)DGA in n-dodecane were subjected to γ- irradiation in the presence and absence of an acidic aqueous phase. These solutions were then analyzed using UHPLC-ESI-MS to determine the rates of radiolytic decay of the two extractants neat and in contact with respect to the acidity of the contacted aqueous phase, as well as to identify radiolysis products. The presence or absence of an acidic aqueous phase was shown to have no influence on the measured decay rates, nor did the side-chain have an influence. A number of radiolysis products were identified, consistent with those previously identified for these two compounds using GC-MS. The identity of these radiolysis products suggests that the bonds most vulnerable to radiolytic attack are those in the dyglycolamide center of these molecules, and not on the side-chains.  The agreement of these results with previous work using GC-MS indicates supports the further use of UHPLC-ESI-MS as a tool for studying diglycolamide extractant systems.

  9. Characterization of Fatty Acids in Crenarchaeota by GC-MS and NMR

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Hamerly, Timothy; Tripet, Brian; Wurch, Louie; Hettich, Robert L.; Podar, Mircea; Bothner, Brian; Copié, Valérie

    2015-01-01

    Lipids composed of condensed isoprenyl units connected to glycerol backbones by ether linkages are a distinguishing feature of Archaea. Data suggesting that fatty acids with linear hydrocarbon chains are present in some Archaea have been available for decades. However, lack of genomic and biochemical evidence for the metabolic machinery required to synthesize and degrade fatty acids has left the field unclear on this potentially significant biochemical aspect. Because lipids are energy currency and cell signaling molecules, their presence in Archaea is significant for understanding archaeal biology. A recent large-scale bioinformatics analysis reignited the debate as to the importance ofmore » fatty acids in Archaea by presenting genetic evidence for the presence of enzymes required for anabolic and catabolic fatty acid metabolism across the archaeal domain. Here, we present direct biochemical evidence from gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR) spectroscopy for the presence of fatty acids in two members of the Crenarchaeota, Sulfolobus solfataricus and Ignicoccus hospitalis . This is the first report providing biochemical data for the existence of fatty acids in these Crenarchaeota, opening new discussions on energy balance and the potential for the discovery of new thermostable enzymes for industry.« less

  10. Staff | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Materials Sciences and Engineering (MSE) Division MSE Home About Staff What's New Research Areas Reports and Activities Science Highlights Principal Investigators' Meetings BES Home About Staff Print Text Size: A A A FeedbackShare Page Name Title Research Area of Responsibility Dr. Linda Horton Division Director Materials Sciences and Engineering Vacant Division Secretary Ms. Teresa Crockett Program Analyst Ashley Dyke Intern Dr. Arvind Kini Team Lead Materials Discovery, Design, and Synthesis

  11. Surface Cleaning Techniques: Ultra-Trace ICP-MS Sample Preparation and Assay of HDPE

    SciTech Connect (OSTI)

    Overman, Nicole R.; Hoppe, Eric W.; Addleman, Raymond S.

    2013-06-01

    The world’s most sensitive radiation detection and assay systems depend upon ultra-low background (ULB) materials to reduce unwanted radiological backgrounds. Herein, we evaluate methods to clean HDPE, a material of interest to ULB systems and the means to provide rapid assay of surface and bulk contamination. ULB level material and ultra-trace level detection of actinide elements is difficult to attain, due to the introduction of contamination from sample preparation equipment such as pipette tips, sample vials, forceps, etc. and airborne particulate. To date, literature available on the cleaning of such polymeric materials and equipment for ULB applications and ultra-trace analyses is limited. For these reasons, a study has been performed to identify an effective way to remove surface contamination from polymers in an effort to provide improved instrumental detection limits. Inductively Coupled Plasma Mass Spectroscopy (ICP-MS) was utilized to assess the effectiveness of a variety of leachate solutions for removal of inorganic uranium and thorium surface contamination from polymers, specifically high density polyethylene (HDPE). HDPE leaching procedures were tested to optimize contaminant removal of thorium and uranium. Calibration curves for thorium and uranium ranged from 15 ppq (fg/mL) to 1 ppt (pg/mL). Detection limits were calculated at 6 ppq for uranium and 7 ppq for thorium. Results showed the most effective leaching reagent to be clean 6 M nitric acid for 72 hour exposures. Contamination levels for uranium and thorium found in the leachate solutions were significant for ultralow level radiation detection applications.

  12. Characterization of Two Different Clay Materials by Thermogravimetry (TG), Differential Scanning Calorimetry (DSC), Dilatometry (DIL) and Mass Spectrometry (MS) - 12215

    SciTech Connect (OSTI)

    Post, Ekkehard; Henderson, Jack B.

    2012-07-01

    An illitic clay containing higher amounts of organic materials was investigated by dilatometry, thermogravimetry and differential scanning calorimetric. The evolved gases were studied during simultaneous TG-DSC (STA) and dilatometer measurements with simultaneous mass spectrometry in inert gas and oxidizing atmosphere. The dilatometer results were compared with the STA-MS results which confirmed and explained the reactions found during heating of the clay, like dehydration, dehydroxylation, shrinkage, sintering, quartz phase transition, combustion or pyrolysis of organics and the solid state reactions forming meta-kaolinite and mullite. The high amount of organic material effects in inert gas atmosphere most probably a reduction of the oxides which leads to a higher mass loss than in oxidizing atmosphere. Due to this reduction an additional CO{sub 2} emission at around 1000 deg. C was detected which did not occur in oxidizing atmosphere. Furthermore TG-MS results of a clay containing alkali nitrates show that during heating, in addition to water and CO{sub 2}, NO and NO{sub 2} are also evolved, leading to additional mass loss steps. These types of clays showed water loss starting around 100 deg. C or even earlier. This relative small mass loss affects only less shrinkage during the expansion of the sample. The dehydroxylation and the high crystalline quartz content result in considerable shrinkage and expansion of the clay. During the usual solid state reaction where the clay structure collapses, the remaining material finally shrinks down to a so-called clinker. With the help of MS the TG steps can be better interpreted as the evolved gases are identified. With the help of the MS it is possible to distinguish between CO{sub 2} and water (carbonate decomposition, oxidation of organics or dehydration/dehydroxylation). The MS also clearly shows that mass number 44 is found during the TG step of the illitic clay at about 900 deg. C in inert gas, which was interpreted

  13. How did contaminants get there?

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    comparison of Ashley Pond in the 1940s and 60 years later. Ashley Pond was named after Detroit businessman Ashley Pond who started the Los Alamos Ranch School in 1917. A comparison...

  14. Project Final Report: Ubiquitous Computing and Monitoring System (UCoMS) for Discovery and Management of Energy Resources

    SciTech Connect (OSTI)

    Tzeng, Nian-Feng; White, Christopher D.; Moreman, Douglas

    2012-07-14

    The UCoMS research cluster has spearheaded three research areas since August 2004, including wireless and sensor networks, Grid computing, and petroleum applications. The primary goals of UCoMS research are three-fold: (1) creating new knowledge to push forward the technology forefronts on pertinent research on the computing and monitoring aspects of energy resource management, (2) developing and disseminating software codes and toolkits for the research community and the public, and (3) establishing system prototypes and testbeds for evaluating innovative techniques and methods. Substantial progress and diverse accomplishment have been made by research investigators in their respective areas of expertise cooperatively on such topics as sensors and sensor networks, wireless communication and systems, computational Grids, particularly relevant to petroleum applications.

  15. Ms. Elizabeth Withers, EIS Document Manager U.S. Department of Energy (DOE), National Nuclear Security Administration (NNSA)

    National Nuclear Security Administration (NNSA)

    August 14, 2002 Ms. Elizabeth Withers, EIS Document Manager U.S. Department of Energy (DOE), National Nuclear Security Administration (NNSA) Office of Los Alamos Site Operations (OLASO) 528 35 th Street Los Alamos, NM 87544 Re: Comments regarding the scope of the Environmental Impact Statement (EIS) for the proposed Chemistry and Metallurgy Research (CMR) Building Replacement (CMRR) Project (CMRRP) at Los Alamos National Laboratory (LANL) (the "CMRRP EIS") Dear Elizabeth - I won't be

  16. Generation, characterization and in vivo biological activity of two distinct monoclonal anti-PEG IgMs

    SciTech Connect (OSTI)

    Hashimoto, Yosuke; Shimizu, Taro; Mima, Yu; Abu Lila, Amr S.; Ishida, Tatsuhiro; Kiwada, Hiroshi

    2014-05-15

    PEGylation, the attachment of polyethylene glycol (PEG) to nanocarriers and proteins, is a widely accepted approach to improving the in vivo efficacy of the non-PEGylated products. However, both PEGylated liposomes and PEGylated proteins reportedly trigger the production of specific antibodies, mainly IgM, against the PEG moiety, which possibly leads to a reduction in safety and therapeutic efficacy of the PEGylated products. In the present study, two monoclonal anti-PEG IgMs — HIK-M09 via immunization with an intravenous injection of PEGylated liposomes (SLs) and HIK-M11 via immunization with a subcutaneous administration of PEGylated ovalbumin (PEG-OVA) were successfully generated. The generated IgMs showed efficient reactivity to mPEG{sub 2000} conjugated to 1,2-distearoyl-sn-glycero-3-phospho-ethanolamine (DSPE), PEGylated liposome (SL) and PEG-OVA. It appears that HIK-M09 recognizes ethoxy (OCH{sub 2}CH{sub 2}) repeat units along with a terminal motif of PEG, while HIK-M11 recognizes only ethoxy repeat units of PEG. Such unique properties allow HIK-M09 to bind with dense PEG. In addition, their impact on the in vivo clearance of the PEGylated products was investigated. It was found that the generated ant-PEG IgMs induced a clearance of SL as they were intravenously administered with SL. Interestingly, the HIK-M11, generated by PEG-OVA, induced the clearance of both SL and PEG-OVA, while the HIK-M09, generated by SL, induced the clearance of SL only. We here revealed that the presence of serum anti-PEG IgM and the subsequent binding of anti-PEG IgM to the PEGylated products are not necessarily related to the enhanced clearance of the products. It appears that subsequent complement activation following anti-PEG IgM binding is the most important step in dictating the in vivo fate of PEGylated products. This study may have implications for the design, development and clinical application of PEGylated products and therapeutics. - Highlights: • Two monoclonal

  17. Many Voices Working for the Community

    Office of Environmental Management (EM)

    Others Present Chloe Ashley, TDEC Jeff Crane, Environmental Protection Agency (EPA), ... Owsley introduced Chloe Ashley as a TDEC intern. Mr. Crane - no comments. Public Comment ...

  18. Benchmarking the New RESRAD-OFFSITE Source Term Model with DUST-MS and GoldSim - 13377

    SciTech Connect (OSTI)

    Cheng, J.J.; Kamboj, S.; Gnanapragasam, E.; Yu, C.

    2013-07-01

    RESRAD-OFFSITE is a computer code developed by Argonne National Laboratory under the sponsorship of U.S. Department of Energy (DOE) and U.S. Nuclear Regulatory Commission (NRC). It is designed on the basis of RESRAD (onsite) code, a computer code designated by DOE and NRC for evaluating soil-contaminated sites for compliance with human health protection requirements pertaining to license termination or environmental remediation. RESRAD-OFFSITE has enhanced capabilities of modeling radionuclide transport to offsite locations and calculating potential radiation exposure to offsite receptors. Recently, a new source term model was incorporated into RESRAD-OFFSITE to enhance its capability further. This new source term model allows simulation of radionuclide releases from different waste forms, in addition to the soil sources originally considered in RESRAD (onsite) and RESRAD-OFFSITE codes. With this new source term model, a variety of applications can be achieved by using RESRAD-OFFSITE, including but not limited to, assessing the performance of radioactive waste disposal facilities. This paper presents the comparison of radionuclide release rates calculated by the new source term model of RESRAD-OFFSITE versus those calculated by DUST-MS and GoldSim, respectively. The focus of comparison is on the release rates of radionuclides from the bottom of the contaminated zone that was assumed to contain radioactive source materials buried in soil. The transport of released contaminants outside of the primary contaminated zone is beyond the scope of this paper. Overall, the agreement between the RESRAD-OFFSITE results and the DUST-MS and GoldSim results is fairly good, with all three codes predicting identical or similar radionuclide release profiles over time. Numerical dispersion in the DUST-MS and GoldSim results was identified as potentially contributing to the disagreement in the release rates. In general, greater discrepancy in the release rates was found for short

  19. Measurement of elemental speciation by liquid chromatography -- inductively coupled plasma mass spectrometry (LC-ICP-MS) with the direct injection nebulizer (DIN)

    SciTech Connect (OSTI)

    Shum, S.

    1993-05-01

    This thesis is divided into 4 parts: elemental speciation, speciation of mercury and lead compounds by microbore column LC-ICP-MS with direct injection nebulization, spatially resolved measurements of size and velocity distributions of aerosol droplets from a direct injection nebulizer, and elemental speciation by anion exchange and size exclusion chromatography with detection by ICP-MS with direct injection nebulization. Tabs, figs, refs.

  20. NanoLC-FT-ICR MS improves proteome coverage attainable for ~3000 laser microdissected breast carcinoma cells

    SciTech Connect (OSTI)

    Umar, Arzu; Luider, Theo N.; Foekens, J. A.; Pasa-Tolic, Liljiana

    2007-01-29

    Genomics and proteomics assays hold great promise for unrevealing molecular events that underlie human disease. Essential to this quest is the ability to effectively analyze clinical samples, but this task is considerably complicated by tissue heterogeneity. Laser capture microdissection (LCM) can be used to selectively isolate targeted cell populations (such as tumor cells) from their native tissue environment. However, the small number of cells that are typically procured by LCM severely limits the proteome coverage and biomarker discovery potential achievable by conventional proteomics platforms. Herein, we report on the use of a nano liquid chromatography-Fourier transform ion clyclotron resonance mass spectrometry (nLC-FTICR MS) platform for analyzing protein digests of approximately 3,000 LCM-derived tumor cells from breast carcinoma tissue, which corresponds to approximately 300 ng of total protein. A total of 2,836 peptides were identified by matching LC-MS data to accurate mass and time (AMT) tag databases that were previously established for the human mammary epithelium and several breast cancer cell lines. The peptide identifications correspond to 1,139 unique proteins confidently identified with 2 or more peptides. Based on categorization by Gene Ontology, identified proteins appear to cover a wide variety of biological functions and cellular compartments. This work demonstrates that a substantial number of proteins can be identified from a limited number of cells using the AMT tag approach and opens a door for high throughput in-depth proteomics analysis of clinical samples.

  1. Study of organic compounds evolved during the co-firing of coal and refuse derived fuel using TG/MS

    SciTech Connect (OSTI)

    Puroshothama, Shobha; Lu, R.; Yang, Xiaodong

    1996-10-01

    The evolution of organic compounds during the combustion of carbonaceous fuel coupled with solid waste disposal and limited landfill space has been a cause for concern. Co-firing high sulfur coal with refuse derived fuel seems an attractive alternative technique to tackle the dual problem of controlling SO{sub x} emissions as well as those of the chlorinated organic toxins. The TG serves to emulate the conditions of the fluidized bed combustor and the MS serves as the detector for evolved gases. This versatile combination is used to study the decomposition pathway as well as predict the conditions at which various compounds are formed and may serve as a means of reducing the formation of these chlorinated organic compounds.

  2. Identification and decay of the 0.48 ms 13/2{sup +} isomer in {sup 181}Hg

    SciTech Connect (OSTI)

    Andreyev, A. N.; Antalic, S.; Saro, S.; Ackermann, D.; Comas, V. F.; Heinz, S.; Heredia, J. A.; Hessberger, F. P.; Khuyagbaatar, J.; Kojouharov, I.; Kindler, B.; Lommel, B.; Mann, R.; Cocolios, T. E.; Elseviers, J.; Huyse, M.; Duppen, P. Van; Venhart, M.; Franchoo, S.; Hofmann, S.

    2009-10-15

    A new isomer with a half-life of 0.48(2) ms was identified in the nuclide {sup 181}Hg, which was produced in the complete fusion reaction {sup 40}Ca+{sup 144}Sm{yields}{sup 184}Pb* at the velocity filter SHIP (GSI, Darmstadt). The isomeric state was tentatively assigned a spin-parity of 13/2{sup +}. We propose that this isomer de-excites by a yet unobserved low-energy, strongly converted {gamma}-ray transition, followed by a newly identified cascade composed of a 90.3 keV M1 and a 71.4 keV E2 {gamma}-ray transition.

  3. A Comparison of the ?-Radiolysis of TODGA and T(EH)DGA Using UHPLC-ESI-MS Analysis

    SciTech Connect (OSTI)

    Zarzana, Chris A.; Groenewold, Gary S.; Mincher, Bruce J.; Mezyk, Stephen P.; Modolo, Giuseppe; Wildens, Andreas; Schmidt, Holgar; Wishart, James F.; Cook, Andrew R.

    2015-03-01

    Solutions of TODGA and T(EH)DGA in n-dodecane were subjected to ?-irradiation in the presence and absence of an aqueous nitric acid phase and analyzed using UHPLC-ESI-MS to determine the rates of radiolytic decay of the two extractants, as well as to identify radiolysis products. The DGA concentrations decreased exponentially with increasing dose, and the measured degradation rate constants were uninfluenced by the presence or absence of an acidic aqueous phase, or by chemical variations in the alkyl side-chains. The DGA degradation was attributed to reactions of the dodecane radical cation, whose kinetics were measured for TODGA using picosecond electron pulse radiolysis to be k2 = (9.72 ± 1.10) × 109 M-1 s-1. The identified radiolysis products suggest that the bonds most vulnerable to radiolytic attack are those in the diglycolamide center of these molecules and not on the side-chains.

  4. Absolute calibration of Kodak Biomax-MS film response to x rays in the 1.5- to 8-keV energy range

    SciTech Connect (OSTI)

    Marshall, F. J.; Knauer, J. P.; Anderson, D.; Schmitt, B. L

    2006-10-15

    The absolute response of Kodak Biomax-MS film to x rays in the range from 1.5- to 8-keV has been measured using a laboratory electron-beam generated x-ray source. The measurements were taken at specific line energies by using Bragg diffraction to produce monochromatic beams of x rays. Multiple exposures were taken on Biomax MS film up to levels exceeding optical densities of 2 as measured by a microdensitometer. The absolute beam intensity for each exposure was measured with a Si(Li) detector. Additional response measurements were taken with Kodak direct exposure film (DEF) so as to compare the results of this technique to previously published calibrations. The Biomax-MS results have been fitted to a semiempirical mathematical model (Knauer et al., these proceedings). Users of the model can infer absolute fluences from observed exposure levels at either interpolated or extrapolated energies. To summarize the results: Biomax MS has comparable sensitivity to DEF film below 3 keV but has reduced sensitivity above 3 keV ({approx}50%). The lower exposure results from thinner emulsion layers, designed for use with phosphor screens. The ease with which Biomax-MS can be used in place of DEF (same format film, same developing process, and comparable sensitivity) makes it a good replacement.

  5. A comparison of the γ-radiolysis of TODGA and T(EH)DGA using UHPLC-ESI-MS analysis

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Chris A. Zarzana; Cook, Andrew R.; Groenewold, Gary S.; Mincher, Bruce J.; Mezyk, Stephen P.; Wilden, Andreas; Schmidt, Holger; Modolo, Giuseppe; Wishart, James F.

    2015-03-11

    Solutions of TODGA and T(EH)DGA in n-dodecane were subjected to γ-irradiation in the presence and absence of an aqueous nitric acid phase and analyzed using UHPLC-ESI-MS to determine the rates of radiolytic decay of the two extractants, as well as to identify radiolysis products. The DGA concentrations decreased exponentially with increasing dose, and the measured degradation rate constants were uninfluenced by the presence or absence of an acidic aqueous phase, or by chemical variations in the alkyl side-chains. The DGA degradation was attributed to reactions of the dodecane radical cation, whose kinetics were measured for TODGA using picosecond electron pulsemore » radiolysis to be k2 = (9.72 ± 1.10) × 109 M–1 s–1. Furthermore, the identified radiolysis products suggest that the bonds most vulnerable to radiolytic attack are those in the diglycolamide center of these molecules and not on the side-chains.« less

  6. Validation predictions of a 13 m/s cross-wind fire for Fuego and the University of Waterloo dataset.

    SciTech Connect (OSTI)

    Brown, Alexander L.; Evans, Gregory Herbert; Gill, Walter; Jarboe, Daniel T.

    2008-03-01

    Detailed herein are the results of a validation comparison. The experiment involved a 2 meter diameter liquid pool of Jet-A fuel in a 13 m/s crosswind. The scenario included a large cylindrical blocking object just down-stream of the fire. It also included seven smaller calorimeters and extensive instrumentation. The experiments were simulated with Fuego. The model included several conduction regions to model the response of the calorimeters, the floor, and the large cylindrical blocking object. A blind comparison was used to compare the simulation predictions with the experimental data. The more upstream data compared very well with the simulation predictions. The more downstream data did not compare very well with the simulation predictions. Further investigation suggests that features omitted from the original model contributed to the discrepancies. Observations are made with respect to the scenario that are aimed at helping an analyst approach a comparable problem in a way that may help improve the potential for quantitative accuracy.

  7. Distributed computing strategies for processing of FT-ICR MS imaging datasets for continuous mode data visualization

    SciTech Connect (OSTI)

    Smith, Donald F.; Schulz, Carl; Konijnenburg, Marco; Kilic, Mehmet; Heeren, Ronald M.

    2015-03-01

    High-resolution Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry imaging enables the spatial mapping and identification of biomolecules from complex surfaces. The need for long time-domain transients, and thus large raw file sizes, results in a large amount of raw data (“big data”) that must be processed efficiently and rapidly. This can be compounded by largearea imaging and/or high spatial resolution imaging. For FT-ICR, data processing and data reduction must not compromise the high mass resolution afforded by the mass spectrometer. The continuous mode “Mosaic Datacube” approach allows high mass resolution visualization (0.001 Da) of mass spectrometry imaging data, but requires additional processing as compared to featurebased processing. We describe the use of distributed computing for processing of FT-ICR MS imaging datasets with generation of continuous mode Mosaic Datacubes for high mass resolution visualization. An eight-fold improvement in processing time is demonstrated using a Dutch nationally available cloud service.

  8. Is LA-12152-MS

    Office of Scientific and Technical Information (OSTI)

    the ABAOUS subroutine UMAT 12 5. The MOR test specimen configuration corresponding to ... There are various ways to handle the test data, but, from the test data, a Weibull ...

  9. Ms. Margaret Owen, Chair

    Office of Environmental Management (EM)

    Community input regarding deactivation and decommissioning (D&D) activities is gathered ... (RODs) for cleanup. Information on the status of RODs and opportunities for input ...

  10. Ms. Margaret Owen, Chair

    Office of Environmental Management (EM)

    recommending that the Department of Energy (DOE) consider using Federal transport and/or disposition funds to relocate designated cultural/historic property items to outside organizations, when the organizations are unable to fund the relocation themselves. As you summarized in your letter, it is the current policy of DOE and Office of Environmental Management (EM) to donate property with cultural or historic value when that property no longer has reuse value to the Government, has been deemed

  11. LA-11224-MS

    Office of Scientific and Technical Information (OSTI)

    ... conduction example. 42 ****** 3-d test mode1(1,4*4*4)***... node 08 001 003 011 013 ... 0.0e+00 res mass0.000000 kg vap mass-.212595e-09 kq energy 33.7959 mj net discharge ...

  12. LA-23336-MS

    Office of Scientific and Technical Information (OSTI)

    do not BCSSBT- ily state or renect those o f the ... It is a white solid with densities that may vary between 4.3-5.2 gcm3 depending on the method of preparation and ...

  13. Ms. Margaret Owen, Chair

    Office of Environmental Management (EM)

    facility in 2006 when the West Valley Demonstration Project (WVDP) began shipping waste drums to NNSS for disposal. While initial shipments were made by truck, this method was...

  14. LA-23336-MS

    Office of Scientific and Technical Information (OSTI)

    ... potential fouling of the heat exchanger are undesirable. The relative resistance to mass transfer of 24 metals and ... Ser. 4, Technology a d Engineering, Vol. 1, R. Hurst and S. ...

  15. LA-10256-MS

    Office of Legacy Management (LM)

    Radiological Survey and Evaluation of the Fallout Area fom the Trinity Test: Chupadera ... Radiological Survey and Evaluation of the Fallout Area from the Trinity Test: Chupadera ...

  16. MS FORTRAN Extended Libraries

    Energy Science and Technology Software Center (OSTI)

    1986-09-01

    DISPPAK is a set of routines for use with Microsoft FORTRAN programs that allows the flexible display of information on the screen of an IBM PC in both text and graphics modes. The text mode routines allow the cursor to be placed at an arbitrary point on the screen and text to be displayed at the cursor location, making it possible to create menus and other structured displays. A routine to set the color ofmore » the characters that these routines display is also provided. A set of line drawing routines is included for use with IBM''s Color Graphics Adapter or an equivalent board (such as the Enhanced Graphics Adapter in CGA emulation mode). These routines support both pixel coordinates and a user-specified set of real number coordinates. SUBPAK is a function library which allows Microsoft FORTRAN programs to calculate random numbers, issue calls to the operating system, read individual characters from the keyboard, perform Boolean and shift operations, and communicate with the I/O ports of the IBM PC. In addition, peek and poke routines, a routine that returns the address of any variable, and routines that can access the system time and date are included.« less

  17. ms.dvi

    Office of Scientific and Technical Information (OSTI)

    to difference images in the context of the Nearby Supernova Factory supernova search. ... feature, but it requires a detailed modeling of the PDF of each feature, including ...

  18. Ms. Maggie Owen, Chair

    Office of Environmental Management (EM)

    Myron Iwanski, Anderson County Mayor Mark Watson, Oak Ridge city Mayor Ron Woody, Roan ... FORS David Adler, EM-92 Melyssa Noe, EM-95 Joy Sager, EM-91 Susan M.Cange, Acting Manager ...

  19. Is LA-12152-MS

    Office of Scientific and Technical Information (OSTI)

    ... its introduction at the Los Alamos National Laboratory, the widely used ABAQUS code has become a production code for many users who deal with stress analysis and heat transfer. ...

  20. Absolute Calibration of Kodak Biomax-MS Film Response to X Rays in the 1.5- to 8-keV Energy Range

    SciTech Connect (OSTI)

    Marshall, F.J.; Knauer, J.P.; Anderson, D.; Schmitt, B.L.

    2006-09-28

    The absolute response of Kodak Biomax-MS film to x rays in the range from 1.5- to 8-keV has been measured using a laboratory e-beam generated x-ray source. The measurements were taken at specific line energies by using Bragg diffraction to produce monochromatic beams of x rays. Multiple exposures were taken on Biomax MS film up to levels exceeding optical densities of 2 as measured by a microdensitometer. The absolute beam intensity for each exposure was measured with a Si(Li) detector. Additional response measurements were taken with Kodak direct exposure film (DEF) so as to compare the results of this technique to previously published calibrations.

  1. Enhancing Biological Analyses with Three Dimensional Field Asymmetric Ion Mobility, Low Field Drift Time Ion Mobility and Mass Spectrometry (FAIMS/IMS-MS) Separations

    SciTech Connect (OSTI)

    Zhang, Xing; Ibrahim, Yehia M.; Chen, Tsung-Chi; Kyle, Jennifer E.; Norheim, Randolph V.; Monroe, Matthew E.; Smith, Richard D.; Baker, Erin Shammel

    2015-06-30

    We report the first evaluation of a platform coupling a high speed field asymmetric ion mobility spectrometry microchip (FAIMS) with drift tube ion mobility and mass spectrometry (IMS-MS). The FAIMS/IMS-MS platform was used to analyze biological samples and simultaneously acquire multidimensional information of detected features from the measured FAIMS compensation fields and IMS drift times, while also obtaining accurate ion masses. These separations thereby increase the overall separation power, resulting increased information content, and provide more complete characterization of more complex samples. The separation conditions were optimized for sensitivity and resolving power by the selection of gas compositions and pressures in the FAIMS and IMS separation stages. The resulting performance provided three dimensional separations, benefitting both broad complex mixture studies and targeted analyses by e.g. improving isomeric separations and allowing detection of species obscured by chemical noise and other interfering peaks.

  2. Fluorescence spectra and biological activity of aerosolized bacillus spores and MS2 bacteriophage exposed to ozone at different relative humidities in a rotating drum

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Ratnesar-Shumate, Shanna; Pan, Yong-Le; Hill, Steven C.; Kinahan, Sean; Corson, Elizabeth; Eshbaugh, Jonathan; Santarpia, Joshua L.

    2015-10-14

    Biological aerosols (bioaerosols) released into the environment may undergo physical and chemical transformations when exposed to atmospheric constituents such as solar irradiation, reactive oxygenated species, ozone, free radicals, water vapor and pollutants. Aging experiments were performed in a rotating drum chamber subjecting bioaerosols, Bacillus thuringiensis Al Hakam (BtAH) spores and MS2 bacteriophages to ozone at 0 and 150 ppb, and relative humidities (RH) at 10%, 50%, and 80+%. Fluorescence spectra and intensities of the aerosols as a function of time in the reaction chamber were measured with a single particle fluorescence spectrometer (SPFS) and an Ultra-Violet Aerodynamic Particle Sizer® Spectrometermore » (UV-APS). Losses in biological activity were measured by culture and quantitative polymerase chain reaction (q-PCR) assay. For both types of aerosols the largest change in fluorescence emission was between 280 and 400 nm when excited at 263 nm followed by fluorescence emission between 380 and 700 nm when excited at 351 nm. The fluorescence for both BtAH and MS2 were observed to decrease significantly at high ozone concentration and high RH when excited at 263 nm excitation. The decreases in 263 nm excited fluorescence are indicative of hydrolysis and oxidation of tryptophan in the aerosols. Fluorescence measured with the UV-APS (355-nm excitation) increased with time for both BtAH and MS2 aerosols. A two log loss of MS2 bacteriophage infectivity was observed in the presence of ozone at ~50% and 80% RH when measured by culture and normalized for physical losses by q-PCR. Viability of BtAH spores after exposure could not be measured due to the loss of genomic material during experiments, suggesting degradation of extracelluar DNA attributable to oxidation. The results of these studies indicate that the physical and biological properties of bioaerosols change significantly after exposure to ozone and water vapor.« less

  3. Fluorescence spectra and biological activity of aerosolized bacillus spores and MS2 bacteriophage exposed to ozone at different relative humidities in a rotating drum

    SciTech Connect (OSTI)

    Ratnesar-Shumate, Shanna; Pan, Yong-Le; Hill, Steven C.; Kinahan, Sean; Corson, Elizabeth; Eshbaugh, Jonathan; Santarpia, Joshua L.

    2015-10-14

    Biological aerosols (bioaerosols) released into the environment may undergo physical and chemical transformations when exposed to atmospheric constituents such as solar irradiation, reactive oxygenated species, ozone, free radicals, water vapor and pollutants. Aging experiments were performed in a rotating drum chamber subjecting bioaerosols, Bacillus thuringiensis Al Hakam (BtAH) spores and MS2 bacteriophages to ozone at 0 and 150 ppb, and relative humidities (RH) at 10%, 50%, and 80+%. Fluorescence spectra and intensities of the aerosols as a function of time in the reaction chamber were measured with a single particle fluorescence spectrometer (SPFS) and an Ultra-Violet Aerodynamic Particle Sizer® Spectrometer (UV-APS). Losses in biological activity were measured by culture and quantitative polymerase chain reaction (q-PCR) assay. For both types of aerosols the largest change in fluorescence emission was between 280 and 400 nm when excited at 263 nm followed by fluorescence emission between 380 and 700 nm when excited at 351 nm. The fluorescence for both BtAH and MS2 were observed to decrease significantly at high ozone concentration and high RH when excited at 263 nm excitation. The decreases in 263 nm excited fluorescence are indicative of hydrolysis and oxidation of tryptophan in the aerosols. Fluorescence measured with the UV-APS (355-nm excitation) increased with time for both BtAH and MS2 aerosols. A two log loss of MS2 bacteriophage infectivity was observed in the presence of ozone at ~50% and 80% RH when measured by culture and normalized for physical losses by q-PCR. Viability of BtAH spores after exposure could not be measured due to the loss of genomic material during experiments, suggesting degradation of extracelluar DNA attributable to oxidation. The results of these studies indicate that the physical and biological properties of bioaerosols change significantly after exposure to ozone and water vapor.

  4. Quantification of Semi-Volatile Oxygenated Components of Pyrolysis Bio-Oil by Gas Chromatography/Mass Spectrometry (GC/MS): Laboratory Analytical Procedure (LAP)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Quantification of Semi-Volatile Oxygenated Components of Pyrolysis Bio-Oil by Gas Chromatography/Mass Spectrometry (GC/MS) Laboratory Analytical Procedure (LAP) Issue Date: March 2, 2016 Earl Christensen and Jack Ferrell National Renewable Energy Laboratory Mariefel V. Olarte and Asanga B. Padmaperuma Pacific Northwest National Laboratory Technical Report NREL/TP-5100-65889 March 2016 NREL is a national laboratory of the U.S. Department of Energy Office of Energy Efficiency & Renewable

  5. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    ... balanced mixture of nitromethane and hydrogen peroxide Armstrong, M R ; Zaug, J M ; ... mixture of nitromethane and hydrogen peroxide Armstrong, M R ; Zaug, J M ; ...

  6. Alternative Fuels Data Center: Airport Shuttles Run on Propane

    Alternative Fuels and Advanced Vehicles Data Center [Office of Energy Efficiency and Renewable Energy (EERE)]

    " Don Duvernay, Airport Shuttle General Manager, Louis Armstrong New Orleans International The Louis Armstrong New Orleans International Airport in the Big Easy uses 27 ...

  7. Kickoff Meeting for New Fuel Cell Projects

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Jason Marcinkoski PNNL - Topic 5 Susan Stenkamp Tim Armstrong ANL - Topic 5 Di-Jia Liu Tim Armstrong LANL - Topic 6 Fernando Garzon John Garbak Award Requirements * ...

  8. Subcellular-level resolution MALDI-MS imaging of maize leaf metabolites by MALDI-linear ion trap-Orbitrap mass spectrometer

    SciTech Connect (OSTI)

    Korte, Andrew R.; Yandeau-Nelson, Marna D.; Nikolau, Basil J.; Lee, Young Jin

    2015-01-25

    A significant limiting factor in achieving high spatial resolution for matrix-assisted laser desorption ionization-mass spectrometry (MALDI-MS) imaging is the size of the laser spot at the sample surface. We present modifications to the beam-delivery optics of a commercial MALDI-linear ion trap-Orbitrap instrument, incorporating an external Nd:YAG laser, beam-shaping optics, and an aspheric focusing lens, to reduce the minimum laser spot size from ~50 μm for the commercial configuration down to ~9 μm for the modified configuration. This improved system was applied for MALDI-MS imaging of cross sections of juvenile maize leaves at 5-μm spatial resolution using an oversampling method. There are a variety of different metabolites including amino acids, glycerolipids, and defense-related compounds were imaged at a spatial resolution well below the size of a single cell. Such images provide unprecedented insights into the metabolism associated with the different tissue types of the maize leaf, which is known to asymmetrically distribute the reactions of C4 photosynthesis among the mesophyll and bundle sheath cell types. The metabolite ion images correlate with the optical images that reveal the structures of the different tissues, and previously known and newly revealed asymmetric metabolic features are observed.

  9. The use of DRIFTS-MS and kinetic studies to determine the role of acetic acid in the palladium-catalyzed vapor-phase synthesis of vinyl acetate

    SciTech Connect (OSTI)

    Augustine, S.M.; Blitz, J.P. (Quantum Chemical Corp., Cincinnati, OH (United States))

    1993-07-01

    Supported palladium catalyzes the synthesis of vinyl acetate (VA) by oxyacetylation of ethylene. Alkali promoters increase activity and selectivity. The role of acetic acid (HOAc) in these processes is not well understood. Activation energy studies show that HOAc alters the catalyst site and lowers the reaction barrier to VA formation. After correction for this effect, the kinetics reveal that as a reagent HOAc is zero order. This is probably due to a strong adsorption of HOAc and Pd which forms the catalyst active phase. Detailed spectroscopic studies support this conclusion. The surface processes on a supported vinyl acetate catalyst were studied using a method which couples diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) with mass spectrometry (MS). The DRIFTS-MS technique combines the capability of selectively analyzing IR-active surface species with sensitive detection of transient reaction products. By comparing the catalyst with mixtures of palladium acetate powder physically dispersed in potassium chloride, it is determined that the active phase on the catalyst is a form of palladium acetate. Compound formation is consistent with the strong chemisorption of HOAc on Pd. Kinetic analysis of temperature-programmed reaction(TPRxn) data suggests that Pd metal or metal oxide adjacent to the active site is important in the reaction mechanism. 25 refs., 10 figs., 2 tabs.

  10. Subcellular-level resolution MALDI-MS imaging of maize leaf metabolites by MALDI-linear ion trap-Orbitrap mass spectrometer

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Korte, Andrew R.; Yandeau-Nelson, Marna D.; Nikolau, Basil J.; Lee, Young Jin

    2015-01-25

    A significant limiting factor in achieving high spatial resolution for matrix-assisted laser desorption ionization-mass spectrometry (MALDI-MS) imaging is the size of the laser spot at the sample surface. We present modifications to the beam-delivery optics of a commercial MALDI-linear ion trap-Orbitrap instrument, incorporating an external Nd:YAG laser, beam-shaping optics, and an aspheric focusing lens, to reduce the minimum laser spot size from ~50 μm for the commercial configuration down to ~9 μm for the modified configuration. This improved system was applied for MALDI-MS imaging of cross sections of juvenile maize leaves at 5-μm spatial resolution using an oversampling method. Theremore » are a variety of different metabolites including amino acids, glycerolipids, and defense-related compounds were imaged at a spatial resolution well below the size of a single cell. Such images provide unprecedented insights into the metabolism associated with the different tissue types of the maize leaf, which is known to asymmetrically distribute the reactions of C4 photosynthesis among the mesophyll and bundle sheath cell types. The metabolite ion images correlate with the optical images that reveal the structures of the different tissues, and previously known and newly revealed asymmetric metabolic features are observed.« less

  11. On the formation of carbonyl sulfide in the reduction of sulfur dioxide by carbon monoxide on lanthanum oxysulfide catalyst: A study by XPS and TPR/MS

    SciTech Connect (OSTI)

    Lau, N.T.; Fang, M. [Hong Kong Univ. of Science and Technology, Clear Water Bay (Hong Kong). Applied Technology Center] [Hong Kong Univ. of Science and Technology, Clear Water Bay (Hong Kong). Applied Technology Center

    1998-10-25

    Both the X-ray photoelectron spectroscopy (XPS) and temperature-programmed reaction, coupled with mass spectrometry (TPR/MS), are used to study the formation of carbonyl sulfide in the reduction of sulfur dioxide on lanthanum oxysulfide catalyst. It was found that the lattice sulfur of the oxysulfide is released and reacts with carbon monoxide to form carbonyl sulfide when the oxysulfide is heated. The oxysulfide is postulated to form sulfur vacancies at a temperature lower than that for the formation of carbonyl sulfide and atomic sulfur is released in the process. The atomic sulfur can either enter the gas phase and leave the oxysulfide catalyst or react with carbon monoxide to form carbonyl sulfide.

  12. The origin of the X-ray emission from the high-velocity cloud MS30.7–81.4–118

    SciTech Connect (OSTI)

    Henley, David B.; Shelton, Robin L.; Kwak, Kyujin E-mail: rls@physast.uga.edu

    2014-08-10

    A soft X-ray enhancement has recently been reported toward the high-velocity cloud MS30.7–81.4–118 (MS30.7), a constituent of the Magellanic Stream. In order to investigate the origin of this enhancement, we have analyzed two overlapping XMM-Newton observations of this cloud. We find that the X-ray enhancement is ∼6' or ∼100 pc across, and is concentrated to the north and west of the densest part of the cloud. We modeled the X-ray enhancement with a variety of spectral models. A single-temperature equilibrium plasma model yields a temperature of (3.69{sub −0.44}{sup +0.47})×10{sup 6} K and a 0.4-2.0 keV luminosity of 7.9 × 10{sup 33} erg s{sup –1}. However, this model underpredicts the on-enhancement emission around 1 keV, which may indicate the additional presence of hotter plasma (T ≳ 10{sup 7} K), or that recombination emission is important. We examined several different physical models for the origin of the X-ray enhancement. We find that turbulent mixing of cold cloud material with hot ambient material, compression or shock heating of a hot ambient medium, and charge exchange reactions between cloud atoms and ions in a hot ambient medium all lead to emission that is too faint. In addition, shock heating in a cool or warm medium leads to emission that is too soft (for reasonable cloud speeds). We find that magnetic reconnection could plausibly power the observed X-ray emission, but resistive magnetohydrodynamical simulations are needed to test this hypothesis. If magnetic reconnection is responsible for the X-ray enhancement, the observed spectral properties could potentially constrain the magnetic field in the vicinity of the Magellanic Stream.

  13. Untargeted metabolomics studies employing NMR and LC–MS reveal metabolic coupling between Nanoarcheum equitans and its archaeal host Ignicoccus hospitalis

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Hamerly, Timothy; Tripet, Brian P.; Tigges, Michelle; Giannone, Richard J.; Wurch, Louie; Hettich, Robert L.; Podar, Mircea; Copié, Valerie; Bothner, Brian

    2014-11-05

    Interactions between species are the basis of microbial community formation and infectious diseases. Systems biology enables the construction of complex models describing such interactions, leading to a better understanding of disease states and communities. However, before interactions between complex organisms can be understood, metabolic and energetic implications of simpler real-world host-microbe systems must be worked out. To this effect, untargeted metabolomics experiments were conducted and integrated with proteomics data to characterize key molecular-level interactions between two hyperthermophilic microbial species, both of which have reduced genomes. Metabolic changes and transfer of metabolites between the archaea Ignicoccus hospitalis and Nanoarcheum equitans weremore » investigated using integrated LC–MS and NMR metabolomics. The study of such a system is challenging, as no genetic tools are available, growth in the laboratory is challenging, and mechanisms by which they interact are unknown. Together with information about relative enzyme levels obtained from shotgun proteomics, the metabolomics data provided useful insights into metabolic pathways and cellular networks of I. hospitalis that are impacted by the presence of N. equitans, including arginine, isoleucine, and CTP biosynthesis. On the organismal level, the data indicate that N. equitans exploits metabolites generated by I. hospitalis to satisfy its own metabolic needs. Lastly, this finding is based on N. equitans’s consumption of a significant fraction of the metabolite pool in I. hospitalis that cannot solely be attributed to increased biomass production for N. equitans. Combining LC–MS and NMR metabolomics datasets improved coverage of the metabolome and enhanced the identification and quantitation of cellular metabolites.« less

  14. NAME ORGANIZATION E-MAIL PHONE

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    (865) 574-2105 (Alternate) Miller, Ruth Oak Ridge Nat'l Laboratory ... Ashley, Tom CWI, Idaho Cleanup Project thomas.ashley@icp.doe.gov (208) 360-3552 McGary, ...

  15. Profiling of adrenocorticotropic hormone and arginine vasopressin in human pituitary gland and tumor thin tissue sections using droplet-based liquid-microjunction surface-sampling-HPLC–ESI-MS–MS

    SciTech Connect (OSTI)

    Kertesz, Vilmos; Calligaris, David; Feldman, Daniel R.; Changelian, Armen; Laws, Edward R.; Santagata, Sandro; Agar, Nathalie Y. R.; Van Berkel, Gary J.

    2015-06-18

    Described here are the results from the profiling of the proteins arginine vasopressin (AVP) and adrenocorticotropic hormone (ACTH) from normal human pituitary gland and pituitary adenoma tissue sections using a fully automated droplet-based liquid microjunction surface sampling-HPLC-ESI-MS/MS system for spatially resolved sampling, HPLC separation, and mass spectral detection. Excellent correlation was found between the protein distribution data obtained with this droplet-based liquid microjunction surface sampling-HPLC-ESI-MS/MS system and those data obtained with matrix assisted laser desorption ionization (MALDI) chemical imaging analyses of serial sections of the same tissue. The protein distributions correlated with the visible anatomic pattern of the pituitary gland. AVP was most abundant in the posterior pituitary gland region (neurohypophysis) and ATCH was dominant in the anterior pituitary gland region (adenohypophysis). The relative amounts of AVP and ACTH sampled from a series of ACTH secreting and non-secreting pituitary adenomas correlated with histopathological evaluation. ACTH was readily detected at significantly higher levels in regions of ACTH secreting adenomas and in normal anterior adenohypophysis compared to non-secreting adenoma and neurohypophysis. AVP was mostly detected in normal neurohypophysis as anticipated. This work demonstrates that a fully automated droplet-based liquid microjunction surface sampling system coupled to HPLC-ESI-MS/MS can be readily used for spatially resolved sampling, separation, detection, and semi-quantitation of physiologically-relevant peptide and protein hormones, such as AVP and ACTH, directly from human tissue. In addition, the relative simplicity, rapidity and specificity of the current methodology support the potential of this basic technology with further advancement for assisting surgical decision-making.

  16. Profiling of adrenocorticotropic hormone and arginine vasopressin in human pituitary gland and tumor thin tissue sections using droplet-based liquid-microjunction surface-sampling-HPLC–ESI-MS–MS

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Kertesz, Vilmos; Calligaris, David; Feldman, Daniel R.; Changelian, Armen; Laws, Edward R.; Santagata, Sandro; Agar, Nathalie Y. R.; Van Berkel, Gary J.

    2015-06-18

    Described here are the results from the profiling of the proteins arginine vasopressin (AVP) and adrenocorticotropic hormone (ACTH) from normal human pituitary gland and pituitary adenoma tissue sections using a fully automated droplet-based liquid microjunction surface sampling-HPLC-ESI-MS/MS system for spatially resolved sampling, HPLC separation, and mass spectral detection. Excellent correlation was found between the protein distribution data obtained with this droplet-based liquid microjunction surface sampling-HPLC-ESI-MS/MS system and those data obtained with matrix assisted laser desorption ionization (MALDI) chemical imaging analyses of serial sections of the same tissue. The protein distributions correlated with the visible anatomic pattern of the pituitary gland.more » AVP was most abundant in the posterior pituitary gland region (neurohypophysis) and ATCH was dominant in the anterior pituitary gland region (adenohypophysis). The relative amounts of AVP and ACTH sampled from a series of ACTH secreting and non-secreting pituitary adenomas correlated with histopathological evaluation. ACTH was readily detected at significantly higher levels in regions of ACTH secreting adenomas and in normal anterior adenohypophysis compared to non-secreting adenoma and neurohypophysis. AVP was mostly detected in normal neurohypophysis as anticipated. This work demonstrates that a fully automated droplet-based liquid microjunction surface sampling system coupled to HPLC-ESI-MS/MS can be readily used for spatially resolved sampling, separation, detection, and semi-quantitation of physiologically-relevant peptide and protein hormones, such as AVP and ACTH, directly from human tissue. In addition, the relative simplicity, rapidity and specificity of the current methodology support the potential of this basic technology with further advancement for assisting surgical decision-making.« less

  17. TITLE AUTHORS SUBJECT SUBJECT RELATED DESCRIPTION PUBLISHER AVAILABILI...

    Office of Scientific and Technical Information (OSTI)

    SRP radioactive waste releases Startup through Ashley C NUCLEAR FUELS ENVIRONMENTAL SCIENCES RADIOACTIVE EFFLUENTS EMISSION ENVIRONMENTAL MATERIALS CONTAMINATION HIGH LEVEL...

  18. FUELS; 54 ENVIRONMENTAL SCIENCES; RADIOACTIVE EFFLUENTS; EMISSION...

    Office of Scientific and Technical Information (OSTI)

    SRP radioactive waste releases. Startup through 1959 Ashley, C. 05 NUCLEAR FUELS; 54 ENVIRONMENTAL SCIENCES; RADIOACTIVE EFFLUENTS; EMISSION; ENVIRONMENTAL MATERIALS;...

  19. A user's guide to the GoldSim/BLT-MS integrated software package:a low-level radioactive waste disposal performance assessment model.

    SciTech Connect (OSTI)

    Knowlton, Robert G.; Arnold, Bill Walter; Mattie, Patrick D.

    2007-03-01

    Sandia National Laboratories (Sandia), a U.S. Department of Energy National Laboratory, has over 30 years experience in the assessment of radioactive waste disposal and at the time of this publication is providing assistance internationally in a number of areas relevant to the safety assessment of radioactive waste disposal systems. In countries with small radioactive waste programs, international technology transfer program efforts are often hampered by small budgets, schedule constraints, and a lack of experienced personnel. In an effort to surmount these difficulties, Sandia has developed a system that utilizes a combination of commercially available software codes and existing legacy codes for probabilistic safety assessment modeling that facilitates the technology transfer and maximizes limited available funding. Numerous codes developed and endorsed by the United States Nuclear Regulatory Commission (NRC) and codes developed and maintained by United States Department of Energy are generally available to foreign countries after addressing import/export control and copyright requirements. From a programmatic view, it is easier to utilize existing codes than to develop new codes. From an economic perspective, it is not possible for most countries with small radioactive waste disposal programs to maintain complex software, which meets the rigors of both domestic regulatory requirements and international peer review. Therefore, revitalization of deterministic legacy codes, as well as an adaptation of contemporary deterministic codes, provides a credible and solid computational platform for constructing probabilistic safety assessment models. This document is a reference users guide for the GoldSim/BLT-MS integrated modeling software package developed as part of a cooperative technology transfer project between Sandia National Laboratories and the Institute of Nuclear Energy Research (INER) in Taiwan for the preliminary assessment of several candidate low

  20. Improved resolution of hydrocarbon structures and constitutional isomers in complex mixtures using Gas Chromatography-Vacuum Ultraviolet-Mass Spectrometry (GC-VUV-MS)

    SciTech Connect (OSTI)

    Aerosol Dynamics Inc; Aerodyne Research, Inc.,; Tofwerk AG, Thun; Isaacman, Gabriel; Wilson, Kevin R.; Chan, Arthur W. H.; Worton, David R.; Kimmel, Joel R.; Nah, Theodora; Hohaus, Thorsten; Gonin, Marc; Kroll, Jesse H.; Worsnop, Doug R.; Goldstein, Allen H.

    2011-09-13

    Understanding the composition of complex hydrocarbon mixtures is important for environmental studies in a variety of fields, but many prevalent compounds cannot be confidently identified using traditional gas chromatography-mass spectrometry (GC-MS) techniques. This work uses vacuum-ultraviolet (VUV) ionization to elucidate the structures of a traditionally"unresolved complex mixture" by separating components by GC retention time, tR, and mass-to-charge ratio, m/Q, which are used to determine carbon number, NC, and the number of rings and double bonds, NDBE. Constitutional isomers are resolved based on tR, enabling the most complete quantitative analysis to date of structural isomers in an environmentally-relevant hydrocarbon mixture. Unknown compounds are classified in this work by carbon number, degree of saturation, presence of rings, and degree of branching, providing structural constraints. The capabilities of this analysis are explored using diesel fuel, in which constitutional isomer distribution patterns are shown to be reproducible between carbon numbers and follow predictable rules. Nearly half of the aliphatic hydrocarbon mass is shown to be branched, suggesting branching is more important in diesel fuel than previously shown. The classification of unknown hydrocarbons and the resolution of constitutional isomers significantly improves resolution capabilities for any complex hydrocarbon mixture.

  1. Identification of volatile butyl rubber thermal-oxidative degradation products by cryofocusing gas chromatography/mass spectrometry (cryo-GC/MS).

    SciTech Connect (OSTI)

    Smith, Jonell Nicole; White, Michael Irvin; Bernstein, Robert; Hochrein, James Michael

    2013-02-01

    Chemical structure and physical properties of materials, such as polymers, can be altered as aging progresses, which may result in a material that is ineffective for its envisioned intent. Butyl rubber formulations, starting material, and additives were aged under thermal-oxidative conditions for up to 413 total days at up to 124 %C2%B0C. Samples included: two formulations developed at Kansas City Plant (KCP) (%236 and %2310), one commercially available formulation (%2321), Laxness bromobutyl 2030 starting material, and two additives (polyethylene AC-617 and Vanax MBM). The low-molecular weight volatile thermal-oxidative degradation products that collected in the headspace over the samples were preconcentrated, separated, and detected using cryofocusing gas chromatography mass spectrometry (cryo-GC/MS). The majority of identified degradation species were alkanes, alkenes, alcohols, ketones, and aldehydes. Observations for Butyl %2310 aged in an oxygen-18 enriched atmosphere (18O2) were used to verify when the source of oxygen in the applicable degradation products was from the gaseous environment rather than the polymeric mixture. For comparison purposes, Butyl %2310 was also aged under non-oxidative thermal conditions using an argon atmosphere.

  2. Gilbert_etal_MS_FIGS

    Office of Scientific and Technical Information (OSTI)

    nanoparticles Benjamin Gilbert* ,1 , Jordan E. Katz 1 , Jonathan D. Denlinger 2 , ... nanoparticles Benjamin Gilbert* ,1 , Jordan E. Katz 1 , Jonathan D. Denlinger 2 , ...

  3. ARM - Datastreams - irt200ms

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    KS (Extended) SGP E10 Browse Data Tyro, KS (Extended) retired SGP E11 Browse Data Byron, OK (Extended) SGP E12 Browse Data Pawhuska, OK (Extended) SGP E13 Browse Data Lamont, OK...

  4. Ms. Maria Galanti Site Coordinator

    Broader source: Energy.gov (indexed) [DOE]

    ... was overcome in the AEP coal yard that was northwest of ... Combustion of PCBs by incineration as approved under Section ... wastes and residuals under 40 CFR 761.79(g), ...

  5. PHYSOR 2014 Template MS Word

    Office of Scientific and Technical Information (OSTI)

    ... Section 3. Section 4 presents the results of the design search, including the fresh core reactivity, once-through and multi-batch performances, and the reactivity coeffi- cients. ...

  6. MS_07_Number_14.pdf

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Mergedsounding VAP: Recent Enhancements David Troyan 1 , Michael Jensen 1 , David Turner 2 , Mark Miller 1 , Jennifer Delamere 3 , Eli Mlawer 3 , Gerald Mace 4 Author Affiliations ...

  7. LA-10733-MS UC-15

    Office of Scientific and Technical Information (OSTI)

    These corrections involve the solution of a rather simple differential equation, a process taught in all elementary courses on differential equations. The solution to this equation ...

  8. PHYSOR 2014 Template MS Word

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... blankets have lower enrichment with respect to the remainder central part of the fuel stack and consist of solid pellets in non IFBA fuel rods, and annular pellets in IFBA rods. ...

  9. Ms. Maria Galanti Site Coordinator

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Galanti: TRANSMITTAL OF Dl CONSTRUCTION COMPLETION REPORT FOR PHASES I AND II OF THE ... from M. Galanti to J. Bradbume, "Construction Completion Report for Phases I and II ...

  10. Ms. Maria Galanti Site Coordinator

    Broader source: Energy.gov (indexed) [DOE]

    Galanti: REVISED CONSTRUCTION COMPLETION REPORT FOR PHASE I OF THE REMOVAL OF THE X-633 ... is SUbmitting the enclosed revised Construction Completion Report for Phase I of the ...

  11. PHYSOR 2014 Template MS Word

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    1 / 21 AP1000 ® PWR REACTOR PHYSICS ANALYSIS WITH VERA-CS AND KENO-VI - PART II: POWER DISTRIBUTION F. Franceschini Westinghouse Electric Co. LLC, Cranberry Township, Pennsylvania, USA francef@westinghouse.com A. T. Godfrey, J. C. Gehin Oak Ridge National Laboratory godfreyat@ornl.gov ABSTRACT Westinghouse has applied the Core Simulator of the Virtual Environment for Reactor Ap- plications, VERA-CS, under development by the Consortium for Advanced Simulation of LWRs (CASL) to the core physics

  12. MS_08_15.pdf

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Jim Mather and Sally McFarlane, PNNL Eli Mlawer and Jennifer Delamere, AER, Inc. Mark Miller, Rutger University Dave Turner, University of Wisconsin Jay Mace, University of Utah...

  13. ARM - Instrument - ptr-ms

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Aerosols This instrument measures low concentrations of volatile organic compounds-important precursors in aerosol formation-in the atmosphere by positively ionizing the...

  14. PHYSOR 2014 Template MS Word

    Office of Scientific and Technical Information (OSTI)

    SIMULATION OF WATTS BAR INITIAL STARTUP TESTS WITH CONTINUOUS ENERGY MONTE CARLO METHODS A. T. Godfrey, J. C. Gehin, K. B. Bekar, C. Celik Oak Ridge National Laboratory Oak Ridge, ...

  15. A survey of Existing V&V, UQ and M&S Data and Knowledge Bases in Support of the Nuclear Energy - Knowledge base for Advanced Modeling and Simulation (NE-KAMS)

    SciTech Connect (OSTI)

    Hyung Lee; Rich Johnson, Ph.D.; Kimberlyn C. Moussesau

    2011-12-01

    The Nuclear Energy - Knowledge base for Advanced Modeling and Simulation (NE-KAMS) is being developed at the Idaho National Laboratory in conjunction with Bettis Laboratory, Sandia National Laboratories, Argonne National Laboratory, Oak Ridge National Laboratory, Utah State University and others. The objective of this consortium is to establish a comprehensive knowledge base to provide Verification and Validation (V&V) and Uncertainty Quantification (UQ) and other resources for advanced modeling and simulation (M&S) in nuclear reactor design and analysis. NE-KAMS will become a valuable resource for the nuclear industry, the national laboratories, the U.S. NRC and the public to help ensure the safe operation of existing and future nuclear reactors. A survey and evaluation of the state-of-the-art of existing V&V and M&S databases, including the Department of Energy and commercial databases, has been performed to ensure that the NE-KAMS effort will not be duplicating existing resources and capabilities and to assess the scope of the effort required to develop and implement NE-KAMS. The survey and evaluation have indeed highlighted the unique set of value-added functionality and services that NE-KAMS will provide to its users. Additionally, the survey has helped develop a better understanding of the architecture and functionality of these data and knowledge bases that can be used to leverage the development of NE-KAMS.

  16. Publications | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    I. S. Archer, C. Archuleta, J. Armstrong, Robert Armstrong, T. G. Arnold, K. Arora, N. ... F. Higdon, D. Hill, C. Hinson, E. Hirsch, P. R. Hittinger, J. Hjorth-Jensen, M. ...

  17. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    ... Filter by Author Allerman, Andrew A. (1) Armstrong, Andrew (1) Crawford, Mary Hagerott (1) ... The Influence of Al Composition on Point Defect Incorporation in AlGaN. Armstrong, Andrew ...

  18. Lab provides environmental support for county construction projects

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Lab provides environmental support for county construction projects Community Connections: Your link to news and opportunities from Los Alamos National Laboratory Latest Issue: September 1, 2016 all issues All Issues » submit Lab provides environmental support for county construction projects A face-lift for Ashley Pond November 1, 2013 Ashley Pond in Los Alamos under construction in the fall of 2013 Ashley Pond in Los Alamos under construction in the fall of 2013 Contact Community Programs

  19. NERSC Hosts Application Readiness and Portability Meeting with...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Antypas, NERSC; Ashley Barker, OLCF; Matt Cordery, NERSC; Jack Deslippe, NERSC; Carter Edwards, SNL; Hal Finkel, ALCF; Fernanda Foertter, OLCF; Scott French, NERSC; Scott Futral,...

  20. Meeting_Summary.pdf

    Broader source: Energy.gov (indexed) [DOE]

    and commercial air conditioning equipment. Representing Ingersoll RandTrane was Jordan Doria, Jill Hootman and David Modi. From the Department were John Cymbalsky and Ashley ...

  1. SciTech Connect:

    Office of Scientific and Technical Information (OSTI)

    Barker, Ashley D" Name Name ORCID Search Authors Type: All BookMonograph ConferenceEvent Journal Article Miscellaneous Patent Program Document Software Manual Technical Report...

  2. Gratiot County, Michigan: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    Climate Zone Number 5 Climate Zone Subtype A. Places in Gratiot County, Michigan Alma, Michigan Ashley, Michigan Breckenridge, Michigan Ithaca, Michigan Perrinton, Michigan...

  3. CNMS User Newsletter

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Free-standing Piezoelectric Ferroelectric Nanostructures from PZT Material Ashley Bernal, 1 Alexander Tselev, 2 Sergei Kalinin, 2 Nazanin Bassiri-Gharb 1 1 G.W. Woodruff...

  4. How did contaminants get there?

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    How did contaminants get there? How did contaminants get there? During the Manhattan Project, Los Alamos hosted thousands of employees, including many Nobel Prize-winning scientists. Historical operations used the best available waste handling methods for that time. August 1, 2013 A comparison of Ashley Pond in the 1940s and 60 years later. Ashley Pond was named after Detroit businessman Ashley Pond who started the Los Alamos Ranch School in 1917. A comparison of Ashley Pond in the 1940s and 60

  5. Crystal Structures of mPGES-1 Inhibitor Complexes Form a Basis...

    Office of Scientific and Technical Information (OSTI)

    Srinivasan ; Backer, Ryan ; Zhang, Aiping ; Russell, Marijane ; Chang, Shawn S. ; Harvey, Anita ; Sloan, Ashley V. ; Fisher, Matthew J. 1 ; Lilly) 2 + Show Author ...

  6. GBTL Workshop Attendees

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... Liz Moore, DOE, Bioenergy Technologies Office Ashley Rose*, BCS Incorporated Bob Rozmiarek, Virent, Inc. Kate Shenk, Biotechnology Industry Organization Wayne Simmons, Sundrop ...

  7. ALS Communications Group

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ALS Communications Group Print From left: Ashley White, Lori Tamura, Keri Troutman, and Carina Braun. The ALS Communications staff maintain the ALS Web site; write and edit all...

  8. September 2013 Most Viewed Documents for Environmental Sciences...

    Office of Scientific and Technical Information (OSTI)

    in vapor compression for refrigeration and air-conditioning in the United States ... Startup through 1959 Ashley, C. (1960) 26 Statistical methods for environmental pollution ...

  9. ashheath | The Ames Laboratory

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    ashheath Ames Laboratory Profile Ashley Heath Lab Assistant-X Simulation, Modeling, & Decision Science 1620 Howe Phone Number: 515-294-3891 Email Address: ashheath

  10. ashleymc | The Ames Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ashleymc Ames Laboratory Profile Ashley Cruikshank Grad Asst-RA Chemical & Biological Sciences 2236 Hach Phone Number: 515-294-7568 Email Address: ashleymc

  11. award

    National Nuclear Security Administration (NNSA)

    Delgado-Goudschaal, Olivarez and Davis. Back row from left, Frances Tillery, Barbara Smith, Teresa Albus, Jeff Gillmore, Tammi Pedro, Randy Lucas, Ashley Hayton and Diane...

  12. Steuben County, Indiana: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    Steuben County, Indiana Steuben County Rural E M C Places in Steuben County, Indiana Angola, Indiana Ashley, Indiana Clear Lake, Indiana Fremont, Indiana Hamilton, Indiana...

  13. Involvement of the [beta]3-[alpha]3 Loop of the Proline Dehydrogenase...

    Office of Scientific and Technical Information (OSTI)

    Authors: Zhu, Weidong ; Haile, Ashley M. ; Singh, Ranjan K. ; Larson, John D. ; Smithen, Danielle ; Chan, Jie Y. ; Tanner, John J. ; Becker, Donald F. 1 ; UMC) 2 + Show Author ...

  14. TITLE AUTHORS SUBJECT SUBJECT RELATED DESCRIPTION PUBLISHER AVAILABILI...

    Office of Scientific and Technical Information (OSTI)

    audit of SRP radioactive waste Ashley C NUCLEAR FUELS ENVIRONMENTAL SCIENCES SAVANNAH RIVER PLANT ENVIRONMENTAL EFFECTS RADIOACTIVE EFFLUENTS EMISSION HIGH LEVEL RADIOACTIVE WASTES...

  15. ENVIRONMENTAL SCIENCES; SAVANNAH RIVER PLANT; ENVIRONMENTAL EFFECTS...

    Office of Scientific and Technical Information (OSTI)

    5 audit of SRP radioactive waste Ashley, C. 05 NUCLEAR FUELS; 54 ENVIRONMENTAL SCIENCES; SAVANNAH RIVER PLANT; ENVIRONMENTAL EFFECTS; RADIOACTIVE EFFLUENTS; EMISSION; HIGH-LEVEL...

  16. TITLE AUTHORS SUBJECT SUBJECT RELATED DESCRIPTION PUBLISHER AVAILABILI...

    Office of Scientific and Technical Information (OSTI)

    audit of SRP radioactive waste Ashley C NUCLEAR FUELS ENVIRONMENTAL SCIENCES ENVIRONMENTAL MATERIALS CONTAMINATION RADIOACTIVE EFFLUENTS EMISSION HIGH LEVEL RADIOACTIVE WASTES...

  17. ENVIRONMENTAL SCIENCES; ENVIRONMENTAL MATERIALS; CONTAMINATION...

    Office of Scientific and Technical Information (OSTI)

    audit of SRP radioactive waste Ashley, C. 05 NUCLEAR FUELS; 54 ENVIRONMENTAL SCIENCES; ENVIRONMENTAL MATERIALS; CONTAMINATION; RADIOACTIVE EFFLUENTS; EMISSION; HIGH-LEVEL...

  18. Clay-sewage sludge co-pyrolysis. A TG-MS and Py-GC study on potential advantages afforded by the presence of clay in the pyrolysis of wastewater sewage sludge

    SciTech Connect (OSTI)

    Ischia, Marco; Maschio, Roberto Dal; Grigiante, Maurizio; Baratieri, Marco

    2011-01-15

    Wastewater sewage sludge was co-pyrolyzed with a well characterized clay sample, in order to evaluate possible advantages in the thermal disposal process of solid waste. Characterization of the co-pyrolysis process was carried out both by thermogravimetric-mass spectrometric (TG-MS) analysis, and by reactor tests, using a lab-scale batch reactor equipped with a gas chromatograph for analysis of the evolved gas phase (Py-GC). Due to the presence of clay, two main effects were observed in the instrumental characterization of the process. Firstly, the clay surface catalyzed the pyrolysis reaction of the sludge, and secondly, the release of water from the clay, at temperatures of approx. 450-500 deg. C, enhanced gasification of part of carbon residue of the organic component of sludge following pyrolysis. Moreover, the solid residue remaining after pyrolysis process, composed of the inorganic component of sludge blended with clay, is characterized by good features for possible disposal by vitrification, yielding a vitreous matrix that immobilizes the hazardous heavy metals present in the sludge.

  19. To: Ms. Dorothy Riehle, FOIA Officer,

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    request. Please advise. We will accept electronic copy. If mailed, please mail to: Don Dickson Government Training Inc. 5372 Sandhamn Place Longboat Key, Florida 34228 Respectfully...

  20. LA-8318-MS Informal Report I

    Office of Scientific and Technical Information (OSTI)

    ... D. (E-3) 2-75 QUANTITATION OF CELL FUSION BY TWENTY-ONE STRAINS OF NEWCASTLE DISEASE VIRUS USING FLOW MICROFLUOROMETRY. J. GEN. VIROL., V.41. P.27-36. 1978. CRAM, L. SCOTT (H-10) ...

  1. WSRC-MS-99-00210

    Office of Scientific and Technical Information (OSTI)

    included standard machining, gas-tungsten arc (GTA) welding, pinch welding, and casting. Each assembly is small enough to hold in two hands and weighs 44 pounds or less....

  2. Microsoft Word - benzyl-ms-Revisednoyellow.doc

    Office of Scientific and Technical Information (OSTI)

    ... Introduction The preparation and reactions of 1,2,4-(Me 3 C) 3 C 5 H 2 2 CeH, ... Cp' 2 CeH and Cp' 2 CeF are monomeric in the solid state and presumably in solution as well. ...

  3. LA-11873-MS The Forster, Dexter, and

    Office of Scientific and Technical Information (OSTI)

    ... This is a theoretical development of phonon energy transfer. It makes no engineering ... TN 37831 prices available from (61S)576-8401, FTS 616-8401 Available 10 the public from ...

  4. Microsoft Word - Fischer_MS.doc

    Office of Scientific and Technical Information (OSTI)

    ... The clock signal of the synchrotron triggers a fast electronic pulser, which launches pulses with a rise time of about 100ps into a waveguide structure. These pump pulses create ...

  5. LA-9252-MS UC-70a

    Office of Legacy Management (LM)

    ... Scientific Committee on the Effects of Atomic Radiation, "Sources and Effects of ... Gogolak, "In situ Ge(Li) and NaI(T1) Gamma-Ray Spectrometry," Health amSafety Laboratory ...

  6. Optimal construction of theoretical spectra for MS/MS spectra identification

    SciTech Connect (OSTI)

    Fridman, Tamah; Protopopescu, Vladimir A; Hurst, Gregory {Greg} B; Borziak, Andrei; Gorin, Andrey A

    2005-01-01

    We derive the optimal number of peaks (defined as the minimum number that provides the required efficiency of spectra identification) in the theoretical spectra as a function of: (i) the experimental accuracy, , of the measured ratio m/z; (ii) experimental spectrum density; (iii) size of the database; (iv) number of peaks in the theoretical spectra; and (v) types of ions that the peaks represent. We show that if theoretical spectra are constructed including b and y ions alone, then for =0.5, which is typical for high throughput data, peptide chains of 8 amino acids or longer can be identified based on the positions of peaks alone, at a rate of false identification below 1%. To discriminate between shorter peptides, additional (e.g., intensity-inferred) information is necessary. We derive the dependence of the probability of false identification on the number of peaks in the theoretical spectra and on the types of ions that the peaks represent. Our results suggest that the class of mass spectrum identification problems for which more elaborate development of fragmentation rules (such as intensity model, etc.) is required, can be reduced to the problems that involve homologous peptides.

  7. Neutron and Nuclear Science To/MS: Distribution From/MS: Stephen...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    I. LANSCE-NS Additional Duty Assignments ALARA Coordinator Ron Nelson Crane Coordinator ... E4. Curriculum: Qualified Crane Operator Training Requirements Curriculum 123 Name Z ...

  8. "FERC423",2007,1,195,"Alabama Power Co",3,"Barry","AL","C","application/vnd.ms-excel","Coal","BIT",45,"IM","SU","County Unknown",999,"MINA PRIBBENOW",289050,22.732,0.5,5.2,217.3

    U.S. Energy Information Administration (EIA) Indexed Site

    7,1,195,"Alabama Power Co",3,"Barry","AL","C","application/vnd.ms-excel","Coal","BIT",45,"IM","SU","County Unknown",999,"MINA PRIBBENOW",289050,22.732,0.5,5.2,217.3 "FERC423",2007,1,195,"Alabama Power Co",3,"Barry","AL","C","application/vnd.ms-excel","Coal","BIT",45,"IM","SU","County

  9. "application/vnd.ms-excel","AEGEAN BUNKERING USA LLC",2,510,"Residual Fuel, Over 1.00% Sulfur",1601,"CHARLESTON, SC","SOUTH CAROLINA",1,"TD","TRINIDAD AND TOBAGO",60,2.06,0,,,,,,

    U.S. Energy Information Administration (EIA) Indexed Site

    RPT_PERIOD","R_S_NAME","LINE_NUM","PROD_CODE","PROD_NAME","PORT_CODE","PORT_CITY","PORT_STATE","PORT_PADD","GCTRY_CODE","CNTRY_NAME","QUANTITY","SULFUR","APIGRAVITY","PCOMP_RNAM","PCOMP_SITEID","PCOMP_SNAM","PCOMP_STAT","STATE_NAME","PCOMP_PADD" "application/vnd.ms-excel","AEGEAN BUNKERING

  10. LANL12-RS-107J PYTHON radiography analysis tool final report...

    Office of Scientific and Technical Information (OSTI)

    Authors: Temple, Brian Allen 1 ; Armstrong, Jerawan Chudoung 1 + Show Author Affiliations Los Alamos National Lab. (LANL), Los Alamos, NM (United States) Publication Date: ...

  11. Howard County, Missouri: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    in Howard County, Missouri Armstrong, Missouri Fayette, Missouri Franklin, Missouri Glasgow, Missouri New Franklin, Missouri Retrieved from "http:en.openei.orgw...

  12. Browse by Discipline -- E-print Network Subject Pathways: Multidiscipl...

    Office of Scientific and Technical Information (OSTI)

    Allain) - Department of Chemistry and Physics, Southeastern Louisiana University Allen, ... (Lloyd Armstrong Jr.) - Department of Physics and Astronomy, University of Southern ...

  13. Advisors | Solid State Solar Thermal Energy Conversion

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Advisors Robert Armstrong Director, MIT Energy Initiative Visit Website George W. Crabtree Senior Scientist, Argonne National Laboratory Argonne Distinguished Fellow Visit Website ...

  14. Hydrogen Fueling Station in Honolulu, Hawaii Feasibility Analysis

    Office of Energy Efficiency and Renewable Energy (EERE)

    This feasibility report assesses the technical and economic feasibility of deploying a hydrogen fueling station at the Fort Armstrong site in Honolulu.

  15. THE 8TH NON-LTE KINETICS WORKSHOP (Conference) | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    Authors: Fontes, Christopher J. 1 ; Armstrong, Gregory 1 ; Colgan, James P. 1 ; Kilcrease, David P. 1 ; Zhang, Honglin 1 + Show Author Affiliations Los Alamos National ...

  16. Missouri's 3rd congressional district: Energy Resources | Open...

    Open Energy Info (EERE)

    congressional district A2Wind Limited Affinity Wind LLC Akermin Inc Armstrong Teasdale Future Energy Group Clean Power Design CleanTech Biofuels International Fuel Technology...

  17. Missouri's 1st congressional district: Energy Resources | Open...

    Open Energy Info (EERE)

    congressional district A2Wind Limited Affinity Wind LLC Akermin Inc Armstrong Teasdale Future Energy Group Clean Power Design CleanTech Biofuels Confluence Solar International...

  18. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    ... Deep Level Characterization: Electrical and Optical Methods - book chapter. Armstrong, Andrew ; Kaplar, Robert Abstract not provided. November 2015 , Springer Ultra-Wide-Bandgap ...

  19. p

    Gasoline and Diesel Fuel Update (EIA)

    ... Armstrong Hutchinson Childress Dallam Collingsworth Hartley Harmon Oldham Cotton Canadian Deaf Smith Kingfisher Grant Hardeman Hale Floyd Lamb Motley Cottle Wilbarger Grady ...

  20. Microsoft Word - EM QA Corporate Board Meeting Minutes - February...

    Office of Environmental Management (EM)

    of Nuclear Safety Ken Armstrong - EMCBC* Russell McCallister - PortsmouthPaducah Mike Brown- Carlsbad Brian Harkins - River Protection Bob Murray (vice-chair) - Headquarters...

  1. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    ... Filter by Author Fuchey, Eric (3) Albataineh, Hisham (2) Aniol, Konrad (2) Armstrong, ... at Jefferson Lab Hall A, to extract the ep yields eppisup 0 crossmore section. ...

  2. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    Kaplar, Robert (12) Allerman, Andrew A. (11) Smith, Mark A. (10) Chow, Weng W. (8) ... Andrew A. ; Armstrong, Andrew M. ; Smith, Michael L. ; Cross, Karen C. We ...

  3. Laser diodes with 353 nm wavelength enabled by reduced-dislocation...

    Office of Scientific and Technical Information (OSTI)

    Authors: Crawford, Mary H. 1 ; Allerman, Andrew A. 1 ; Armstrong, Andrew M. 1 ; Smith, Michael L. 1 ; Cross, Karen C. 1 + Show Author Affiliations Sandia National Lab. ...

  4. Final LDRD report : science-based solutions to achieve high-performanc...

    Office of Scientific and Technical Information (OSTI)

    Authors: Armstrong, Andrew M. ; Miller, Mary A. ; Crawford, Mary Hagerott ; Alessi, Leonard J. ; Smith, Michael L. ; Henry, Tanya A. ; Westlake, Karl R. ; Cross, Karen Charlene ; ...

  5. Neppel Wind Power Project | Open Energy Information

    Open Energy Info (EERE)

    Developer Alliant Energy Energy Purchaser AlliantIES Utilities Location Armstrong IA Coordinates 43.402001, -94.578989 Show Map Loading map... "minzoom":false,"mappings...

  6. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    ... Allada, Kalyan (2) Armstrong, Whitney (2) Averett, Todd (2) Bertozzi, William (2) Boeglin, Werner (2) Camsonne, Alexandre (2) Daniel, Aji (2) Deconinck, Wouter (2) Flay, David (2) ...

  7. "Title","Creator/Author","Publication Date","OSTI Identifier...

    Office of Scientific and Technical Information (OSTI)

    subsequent to shock in an unreacted, oxygen balanced mixture of nitromethane and hydrogen peroxide","Armstrong, M R; Zaug, J M; Grant, C D; Crowhurst, J C; Bastea,...

  8. Search for: All records | SciTech Connect

    Office of Scientific and Technical Information (OSTI)

    ... Armstrong, Whitney (3) Averett, Todd (3) Benmokhtar, Fatiha (3) Camsonne, Alexandre (3) Chen, Chunhua (3) Dalton, Mark (3) Deconinck, Wouter (3) Flay, David (3) Friend, Megan (3) ...

  9. St. Louis, Missouri: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    Limited Affinity Wind LLC Akermin Inc Armstrong Teasdale Future Energy Group Clean Power Design CleanTech Biofuels International Fuel Technology Inc Secure Energy Inc Solar...

  10. Method for generation of THz frequency radiation and sensing...

    Office of Scientific and Technical Information (OSTI)

    Inventors: Reed, Evan J. 1 ; Armstrong, Michael R. 2 + Show Author Affiliations (Pine Island, MN) (Albuquerque, NM) Issue Date: 2010-09-07 OSTI Identifier: 1014664 Assignee: ...