Sample records for mri midwest research

  1. Operated for the U.S. Department of Energy by Midwest Research Institute Battelle Bechtel National Renewable Energy Laboratory

    E-Print Network [OSTI]

    Operated for the U.S. Department of Energy by Midwest Research Institute · Battelle · Bechtel #12;Operated for the U.S. Department of Energy by Midwest Research Institute · Battelle · Bechtel Institute · Battelle · Bechtel National Renewable Energy Laboratory Material and Energetic Criteria ·Band

  2. Reducing Health Disparities The Midwest Latino Health Research, Training and Policy Center (MLHRC) is a

    E-Print Network [OSTI]

    Illinois at Chicago, University of

    . The center is studying access to care and health disparities among underserved and minority women with breastReducing Health Disparities The Midwest Latino Health Research, Training and Policy Center (MLHRC of Excellence, and the UIC School of Public Health. MLHRC began with a minority research center on the Medical

  3. Original Research Comparison of MRI and 18

    E-Print Network [OSTI]

    Delp, Scott

    - age in the bone or cartilage as seen on MRI. Conclusion: Our results suggest that 18 F-NaF PET/CT may in increased tracer uptake (7). While 18F-NaF PET/CT is more expensive than Tc-99m MDP bone scintigraphy, there are a number of benefits of this modality. The advantages of 18 F-NaF PET/CT over bone scintigraphy techniques

  4. Clean Energy Manufacturing Initiative Midwest Regional Summit...

    Office of Environmental Management (EM)

    Clean Energy Manufacturing Initiative Midwest Regional Summit: Lightweighting Breakout Session Summary Clean Energy Manufacturing Initiative Midwest Regional Summit: Lightweighting...

  5. 72nd Midwest PDE Seminar

    E-Print Network [OSTI]

    2013-11-13T23:59:59.000Z

    72nd Midwest PDE Seminar. Purdue University, November 16–17, 2013. Charles Smart, MIT. Sat, Nov 16, 3:00–3:50, MATH 175. Quantitative stochastic ...

  6. MEEA Midwest Energy Solutions Conference

    Broader source: Energy.gov [DOE]

    Midwest Energy Efficiency Alliance (MEEA) is hosting its annual conference at the Chicago Hilton and Towers in Chicago, IL, on Jan. 28-30, 2015.

  7. Midwest Building Energy Program

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't YourTransport(FactDepartment3311,Official FileEnergy Midsize Wind Turbines for theMidwest

  8. Coordination of Retail Demand Response with Midwest ISO Markets

    E-Print Network [OSTI]

    Bharvirkar, Ranjit

    2008-01-01T23:59:59.000Z

    Serving Entity Midwest Independent System Operator Marketin the Midwest Independent System Operator (MISO) region and2007). The Midwest Independent System Operator (MISO) called

  9. Coordination of Retail Demand Response with Midwest ISO Markets

    E-Print Network [OSTI]

    Bharvirkar, Ranjit

    2008-01-01T23:59:59.000Z

    M T E P 06 - The Midwest ISO Transmission Expansion Plan,Demand Response in Midwest ISO Market," Presentation at MISODemand Response with Midwest ISO Wholesale Markets Ranjit

  10. Midwest Hydro Users Group Meeting

    Broader source: Energy.gov [DOE]

    The Midwest Hydro Users Group will be holding their annual Fall meeting on November 12th and 13th in Wausau, Wisconsin.  An Owners-only meeting on the afternoon of the 12th followed by a full...

  11. INVESTIGATION OF BULK POWER MIDWEST REGION

    E-Print Network [OSTI]

    Laughlin, Robert B.

    INVESTIGATION OF BULK POWER MARKETS MIDWEST REGION November 1, 2000 The analyses and conclusions Energy Regulatory Commission, any individual Commissioner, or the Commission itself #12;3-i Contents Page . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2-3 A. Description of the Midwest

  12. Midwest Forensics Resource Center | The Ames Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > The EnergyCenterDioxide Capture in the PresenceEnergyMolecularMidwest

  13. Midwest Transmission Workshop I Summary

    SciTech Connect (OSTI)

    Kevin Bryan

    2001-05-01T23:59:59.000Z

    OAK-B135 The meeting was opened with a review of the purposes of the workshop: (1) Present and discuss key studies and assessments of transmission upgrades, additions and related issues for the upper Midwest, including work that addresses the full range of views on these topics; (2) Understand the various transmission issues in the upper Midwest and discuss options for addressing the issues; and (3) Identify the decision makers and entities that need to play an active role if transmission issues are to be resolved, and agree on next steps for engaging these individuals and organizations through education, outreach, and information dissemination.

  14. Advanced Vehicles and Fuels Systems: Cooperative Research and Development Final Report, CRADA number CRD-03-00129

    SciTech Connect (OSTI)

    Farrington, R. B.

    2010-07-01T23:59:59.000Z

    Midwest Research Institute (MRI) and AVL Powertrain Engineering, Inc. (AVL) have executed a Software and Trademark License Agreement (Software License) by which AVL is granted the exclusive right to use, modify and improve and to commercialize by reproducing, distributing and granting sublicenses in, certain computer software known as ADVISOR 2003.

  15. Midwest Clean Energy Application Center

    SciTech Connect (OSTI)

    Cuttica, John; Haefke, Cliff

    2013-12-31T23:59:59.000Z

    The Midwest Clean Energy Application Center (CEAC) was one of eight regional centers that promoted and assisted in transforming the market for combined heat and power (CHP), waste heat to power (WHP), and district energy (DE) technologies and concepts throughout the United States between October 1, 2009 and December 31, 2013. The key services the CEACs provided included: ? Market Opportunity Analyses – Supporting analyses of CHP market opportunities in diverse markets including industrial, federal, institutional, and commercial sectors. ? Education and Outreach – Providing information on the energy and non-energy benefits and applications of CHP to state and local policy makers, regulators, energy end-users, trade associations and others. Information was shared on the Midwest CEAC website: www.midwestcleanergy.org. ? Technical Assistance – Providing technical assistance to end-users and stakeholders to help them consider CHP, waste heat to power, and/or district energy with CHP in their facility and to help them through the project development process from initial CHP screening to installation. The Midwest CEAC provided services to the Midwest Region that included the states of Illinois, Indiana, Iowa, Kansas, Michigan, Minnesota, Missouri, Nebraska, North Dakota, Ohio, South Dakota, and Wisconsin.

  16. Midwest Transmission Workshop II Summary

    SciTech Connect (OSTI)

    Kevin Bryan

    2002-12-05T23:59:59.000Z

    OAK-B135 After introductions of all participants, Abby Arnold, RESOLVE, reviewed the purpose of the meeting and the agenda. The purpose of the workshop was to share the results of the Midwest Independent System Operator (MISO) scenario development for wind and other fuel sources and the corresponding implications for transmission throughout the MISO control area. The workshop agenda is included in Attachment A.

  17. Midwest Renewable Energy Tracking System (Multiple States)

    Broader source: Energy.gov [DOE]

    The Midwest Renewable Energy Tracking System (M-RETS®) tracks renewable energy generation in participating States and Provinces and assists in verifying compliance with individual state/provincial...

  18. Coordination of Retail Demand Response with Midwest ISO Markets

    E-Print Network [OSTI]

    Bharvirkar, Ranjit

    2008-01-01T23:59:59.000Z

    Robinson, Michael, 2008, "Demand Response in Midwest ISOPresentation at MISO Demand Response Working Group Meeting,Coordination of Retail Demand Response with Midwest ISO

  19. EERE Leadership Discusses Energy Innovation in Midwest | Department...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    EERE Leadership Discusses Energy Innovation in Midwest EERE Leadership Discusses Energy Innovation in Midwest October 28, 2014 - 3:06pm Addthis EERE Leadership Discusses Energy...

  20. State and Local Code Implementation: Midwest Region - 2014 BTO...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Code Implementation: Midwest Region - 2014 BTO Peer Review Presenter: Isaac Elencave, Midwest Energy Efficiency Alliance View the Presentation State and Local Code...

  1. Midwest Nuclear Science and Engineering Consortium

    SciTech Connect (OSTI)

    Dr. Wynn Volkert; Dr. Arvind Kumar; Dr. Bryan Becker; Dr. Victor Schwinke; Dr. Angel Gonzalez; Dr. DOuglas McGregor

    2010-12-08T23:59:59.000Z

    The objective of the Midwest Nuclear Science and Engineering Consortium (MNSEC) is to enhance the scope, quality and integration of educational and research capabilities of nuclear sciences and engineering (NS/E) programs at partner schools in support of the U.S. nuclear industry (including DOE laboratories). With INIE support, MNSEC had a productive seven years and made impressive progress in achieving these goals. Since the past three years have been no-cost-extension periods, limited -- but notable -- progress has been made in FY10. Existing programs continue to be strengthened and broadened at Consortium partner institutions. The enthusiasm generated by the academic, state, federal, and industrial communities for the MNSEC activities is reflected in the significant leveraging that has occurred for our programs.

  2. What's happening in Midwest ISO market?

    E-Print Network [OSTI]

    Tesfatsion, Leigh

    -ahead and real- time markets were significantly lower in 2006. Lower natural gas prices Improved coordination attributable to significantly decreased natural gas, oil and coal prices. (fuel costs represent the vastWhat's happening in Midwest ISO market? Review of 2006 Market report for Midwest ISO Department

  3. Undergraduate Research Aide Appointment | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Undergraduates Internship Opportunities Temporary Employment Research Aide Appointment Undergraduate Symposium Louis Stokes Midwest Center for Excellence Research Catalog Contact...

  4. Midwest Transmission Workshop III Summary

    SciTech Connect (OSTI)

    Kevin Bryan

    2003-03-12T23:59:59.000Z

    OAK-B135 On March 12-13, 2002, the National Wind Coordinating Committee (NWCC), in cooperation with regional stakeholders, held a two-day workshop: Planning for Electrical Transmission Needs in the Upper Midwest. The workshop was the outgrowth of an effort to develop a forum and process for consideration of transmission options that strives for equitable allocation of benefits and impacts among all affected parties. The goal of this workshop was to provide a catalyst for an enhanced, inclusive process for transmission planning with participation of and acceptance by all affected stakeholders. Participants in the meeting included representatives of state and regional regulatory agencies, utilities and power generators, the wind industry, environmental and landowner interests, and other interested parties (see Attachment A for a list of meeting participants).

  5. Midwest Independent System Operator (Multiple States)

    Broader source: Energy.gov [DOE]

    Midwest Independent Transmission System Operator (MISO) is a Regional Transmission Organization, which administers wholesale electricity markets in all or parts of 11 U.S. states and the Canadian...

  6. Midwest Electric, Inc | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directedAnnual SiteofEvaluatingGroup |JilinLu anMicrogreen Polymers Inc Jump to:Jump to:MiddleMidwestMidwest

  7. The potential impacts of a competitive wholesale market in the midwest: A preliminary examination of centralized dispatch

    E-Print Network [OSTI]

    Lesieutre, Bernard C.; Bartholomew, Emily; Eto, Joseph H.; Hale, Douglas; Luong, Thanh

    2004-01-01T23:59:59.000Z

    Impacts of a Competitive Wholesale Market in the Midwest: AImpacts of a Competitive Wholesale Market in the Midwest: AImpacts of a Competitive Wholesale Market in the Midwest: A

  8. The potential impacts of a competitive wholesale market in the midwest: A preliminary examination of centralized dispatch

    E-Print Network [OSTI]

    Lesieutre, Bernard C.; Bartholomew, Emily; Eto, Joseph H.; Hale, Douglas; Luong, Thanh

    2004-01-01T23:59:59.000Z

    Company Midwest Independent System Operator Minnesota Power2005, the Midwest Independent System Operator (MISO) will2005, the Midwest Independent System Operator (MISO) will

  9. MIDWEST REGIONAL CARBON SEQUESTRATION PARTNERSHIP (MRCSP)

    SciTech Connect (OSTI)

    David Ball; Judith Bradbury; Rattan Lal; Larry Wickstrom; Neeraj Gupta; Robert Burns; Bob Dahowski

    2004-04-30T23:59:59.000Z

    This is the first semiannual report for Phase I of the Midwest Carbon Sequestration Partnership (MRCSP). The project consists of nine tasks to be conducted over a two year period that started in October 2003. The makeup of the MRCSP and objectives are described. Progress on each of the active Tasks is also described and where possible, for those Tasks at some point of completion, a summary of results is presented.

  10. Department of Bioengineering Spring 2013 MRI Compatible Gustometer for Childhood Obesity Research

    E-Print Network [OSTI]

    Demirel, Melik C.

    PENNSTATE Department of Bioengineering Spring 2013 MRI Compatible Gustometer for Childhood Obesity or obesity. A need exists to better understand the neurological perception of taste in order to create better

  11. The Midwest Regional Carbon Sequestration Partnership (MRCSP)

    SciTech Connect (OSTI)

    James J. Dooley; Robert Dahowski; Casie Davidson

    2005-12-01T23:59:59.000Z

    This final report summarizes the Phase I research conducted by the Midwest regional Carbon Sequestration Partnership (MRCSP). The Phase I effort began in October 2003 and the project period ended on September 31, 2005. The MRCSP is a public/private partnership led by Battelle with the mission of identifying the technical, economic, and social issues associated with implementation of carbon sequestration technologies in its seven state geographic region (Indiana, Kentucky, Maryland, Michigan, Ohio, Pennsylvania, and West Virginia) and identifying viable pathways for their deployment. It is one of seven partnerships that together span most of the U.S. and parts of Canada that comprise the U.S. Department of Energy's (DOE's) Regional Carbon Sequestration Program led by DOE's national Energy Technology Laboratory (NETL). The MRCSP Phase I research was carried out under DOE Cooperative Agreement No. DE-FC26-03NT41981. The total value of Phase I was $3,513,513 of which the DOE share was $2,410,967 or 68.62%. The remainder of the cost share was provided in varying amounts by the rest of the 38 members of MRCSP's Phase I project. The next largest cost sharing participant to DOE in Phase I was the Ohio Coal Development Office within the Ohio Air Quality Development Authority (OCDO). OCDO's contribution was $100,000 and was contributed under Grant Agreement No. CDO/D-02-17. In this report, the MRCSP's research shows that the seven state MRCSP region is a major contributor to the U. S. economy and also to total emissions of CO2, the most significant of the greenhouse gases thought to contribute to global climate change. But, the research has also shown that the region has substantial resources for sequestering carbon, both in deep geological reservoirs (geological sequestration) and through improved agricultural and land management practices (terrestrial sequestration). Geological reservoirs, especially deep saline reservoirs, offer the potential to permanently store CO2 for literally 100s of years even if all the CO2 emissions from the region's large point sources were stored there, an unlikely scenario under any set of national carbon emission mitigation strategies. The terrestrial sequestration opportunities in the region have the biophysical potential to sequester up to 20% of annual emissions from the region's large point sources of CO2. This report describes the assumptions made and methods employed to arrive at the results leading to these conclusions. It also describes the results of analyses of regulatory issues in the region affecting the potential for deployment of sequestration technologies. Finally, it describes the public outreach and education efforts carried out in Phase I including the creation of a web site dedicated to the MRCSP at www.mrcsp.org.

  12. EIA - Natural Gas Pipeline System - Midwest Region

    Annual Energy Outlook 2013 [U.S. Energy Information Administration (EIA)]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742 33 111 1,613 122 40Coal Stocks at1,066,688 760,877 951,322DevelopmentConfigurationMidwest Region

  13. Midwest Underground Technology | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are beingZealand Jump to: navigation, searchOfRose BendMiasole Inc JumpMicroPlanet Name: Midwest IndependentCredits

  14. Midwest Biodiesel Products | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov YouKizildere I Geothermal Pwer Plant JumpMarysville, Ohio:Menomonee| OpenMickeyDelaware: EnergyMidnight PointMidway,Midwest

  15. Midwest, Wyoming: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov YouKizildere I Geothermal Pwer Plant JumpMarysville, Ohio:Menomonee| OpenMickeyDelaware:Midwest, Wyoming: Energy Resources

  16. Midwest Electric Member Corp | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directedAnnual SiteofEvaluatingGroup |JilinLu anMicrogreen Polymers Inc Jump to:Jump to:MiddleMidwest

  17. Midwest Energy Inc | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directedAnnual SiteofEvaluatingGroup |JilinLu anMicrogreen Polymers Inc Jump to:JumpMidwest Energy Inc Jump

  18. Midwest Building Energy Program | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onYouTube YouTube Note: Since the.pdfBreaking ofOil &315_ArnibanPriority DataPART 970Midwest Building Energy Program

  19. Technical Report: Impacts of Land Management and Climate on Agroecosystem Greenhouse Gas Exchange in the Upper Midwest United States

    SciTech Connect (OSTI)

    Timothy J. Griffis; John M. Baker

    2007-07-01T23:59:59.000Z

    Our research is designed to improve the scientific understanding of how carbon is cycled between the land and atmosphere within a heavily managed landscape that is characteristic of the Upper Midwest. The Objectives are: 1) Quantify the seasonal and interannual variation of net ecosystem CO2 exchange of agricultural ecosystems in the Upper Midwest grown under different management strategies; 2) Partition net ecosystem CO2 exchange into photosynthesis and ecosystem respiration by combining micrometeorological and stable isotope techniques; 3) Examine the seasonal variation in canopy-scale photosynthetic discrimination and the isotope ratios of ecosystem respiration and photosynthesis.

  20. Coordination of Retail Demand Response with Midwest ISO Markets

    E-Print Network [OSTI]

    Bharvirkar, Ranjit

    2008-01-01T23:59:59.000Z

    ER08-___-000," December 31. MISO, 2007b, M T E P 06 - TheMidwest ISO Transmission Expansion Plan, February. MISO,2007c, "MISO Press Release," U R L : http://

  1. MIE Regional Climate Change Impact Webinar Series: Midwest

    Office of Energy Efficiency and Renewable Energy (EERE)

    The U.S. Department of Energy's (DOE's) Minorities in Energy Initiative (MIE) is hosting a webinar on Midwest impacts of climate change on minority and tribal communities featuring presentations by...

  2. Midwest Quantitative Biology Conference Mission Point Resort, Mackinac Island, Michigan

    E-Print Network [OSTI]

    Midwest Quantitative Biology Conference Mission Point Resort, Mackinac Island, Michigan September Exchange Method for the Free Energy of Conformational Fluctuations Michigan State University 3:05-3:30 Role

  3. Coordination of Retail Demand Response with Midwest ISO Markets

    E-Print Network [OSTI]

    Bharvirkar, Ranjit

    2008-01-01T23:59:59.000Z

    Data Collection for Demand-side Management for QualifyingPrepared by Demand-side Management Task Force of the4. Status of Demand Side Management in Midwest ISO 5.

  4. Evaluation of Wind Shear Patterns at Midwest Wind Energy Facilities: Preprint

    SciTech Connect (OSTI)

    Smith, K.; Randall, G.; Malcolm, D.; Kelley, N.; Smith, B.

    2002-05-01T23:59:59.000Z

    The U.S. Department of Energy-Electric Power Research Institute (DOE-EPRI) Wind Turbine Verification Program (TVP) has included several wind energy facilities in the Midwestern United States. At several of these projects, a strong diurnal shear pattern has been observed. During the day, low and sometimes negative shear has been measured. During night hours, very high positive shear is frequently observed. These high nighttime shear values are of concern due to the potential for high stresses across the rotor. The resulting loads on turbine components could result in failures. Conversely, the effects of high nighttime wind shear could benefit wind generated energy production in the Midwest by providing a source of greater hub-height wind speeds, particularly for multi-megawatt turbines that utilize tall towers. This paper presents an overview of the observed wind shear at each of the Midwest TVP projects, focusing on diurnal patterns and the frequency of very high nighttime shear at the sites. Turbine fault incidence is examined to determine the presence or absence of a correlation to periods of high shear. Implications of shear-related failures are discussed for other Midwest projects that use megawatt-scale turbines. In addition, this paper discusses the importance of accurate shear estimates for project development.

  5. Day-Ahead premiums on the Midwest ISO

    SciTech Connect (OSTI)

    Bowden, Nicholas; Hu, Su; Payne, James

    2009-03-15T23:59:59.000Z

    An examination of day-ahead premiums for the Midwest ISO from September 2005 to December 2007 reveals that premiums are positive and statistically significant across all five hubs, indicating inefficiency in the Midwest wholesale electricity market. Further, day-ahead premiums exhibit monthly seasonal variation with some indication of the day-ahead premiums declining over time in three of the five hubs. (author)

  6. The Potential Impacts of a Competitive Wholesale Market in the Midwest: A Preliminary Examination of

    E-Print Network [OSTI]

    LBNL-56503 The Potential Impacts of a Competitive Wholesale Market in the Midwest: A Preliminary-56503 The Potential Impacts of a Competitive Wholesale Market in the Midwest: A Preliminary Examination Wholesale Market in the Midwest: A Preliminary Examination of Centralized Dispatch ii Acknowledgements

  7. A Midwest Regional Inventory of Heavy-Duty Diesel Vehicle Emissions

    E-Print Network [OSTI]

    Wisconsin at Madison, University of

    A Midwest Regional Inventory of Heavy-Duty Diesel Vehicle Emissions by Christopher D. Dresser OF WISCONSIN - MADISON Abstract A Midwest Regional Inventory of Heavy-Duty Diesel Vehicle Emissions Christopher-duty diesel vehicles (HDDV) for a ten-state Midwest region (Mississippi Valley Freight Coalition) using

  8. Midwest Appropriate Technology Small Grants Program technical services. Final report

    SciTech Connect (OSTI)

    Not Available

    1984-03-01T23:59:59.000Z

    A total of 84 completed projects were reviewed, assessed, and summarized. These projects were also analyzed to determine characteristics of success and failure. Two significant documents resulted: Midwest ATSGP Project Summaries (DOE/CH/10122-19) and Midwest ATSGP Management Analysis (DOE/CH/10122-18). Additionally, 17 active projects were monitored. All grantees were contacted by telephone and 15 sites were visited. Technical assistance was provided to seven of the active grantees. Three grantees were found to be having serious difficulty. Information dissemination activities were limited at DOE-Chicago direction. Presentations at a meeting of state energy agency representatives and the American Solar Energy Society annual meeting were the highlights. Overall, DOE-Chicago was provided important assistance and documentation on the Midwest ATSGP. In addition, several grantees were assisted in the conduct of their project. A complete timetable of activities is included as Appendix E.

  9. Upper Midwest Food, Fuel and Fiber Network Tour

    E-Print Network [OSTI]

    2nd Annual Upper Midwest Food, Fuel and Fiber Network Tour Aug. 31 ­ Sept. 2, 2010 #12;Tuesday Dept. of Ag & Biological Engineering 9:30 a.m. Horizon Wind Energy Farm ­ (Construction vs. Finished Phases) http://www.horizonwind.com/home/ Gary Freymiller, WISER & Peter Park, Horizon Wind Energy 11:00 a

  10. Midwest Energy (Gas and Electric)- How$mart Energy Efficiency Finance Program

    Broader source: Energy.gov [DOE]

    Midwest Energy offers its residential and small commercial electricity and natural gas customers in good standing a way to finance energy efficiency improvements on eligible properties. Under the...

  11. Mapping the Midwest Future Kevin D. Kephart

    E-Print Network [OSTI]

    Levinson, David M.

    ;#12;· Five Regional University Centers #12;Bioenergy #12;Biomass Feedstocks Research · More than 200 projects, sustainable, affordable, commercial-scale biomass feedstocks is our first key enabler t

  12. MIDWEST REGIONAL CARBON SEQUESTRATION PARTNERSHIP (MRCSP) MANAGING CLIMATE CHANGE AND SECURING A FUTURE FOR THE MIDWEST'S INDUSTRIAL BASE

    SciTech Connect (OSTI)

    David Ball; Robert Burns; Judith Bradbury; Bob Dahowski; Casie Davidson; James Dooley; Neeraj Gupta; Rattan Lal; Larry Wickstrom

    2005-04-29T23:59:59.000Z

    This is the third semiannual report for Phase I of the Midwest Carbon Sequestration Partnership (MRCSP). The project consists of nine tasks to be conducted over a two-year period that started in October 2003. The makeup of the MRCSP and objectives are described. Progress on each of the active Tasks is also described and where possible, for those Tasks at some point of completion, a summary of results is presented.

  13. Portable MRI

    SciTech Connect (OSTI)

    Espy, Michelle A. [Los Alamos National Laboratory

    2012-06-29T23:59:59.000Z

    This project proposes to: (1) provide the power of MRI to situations where it presently isn't available; (2) perform the engineering required to move from lab to a functional prototype; and (3) leverage significant existing infrastructure and capability in ultra-low field MRI. The reasons for doing this: (1) MRI is the most powerful tool for imaging soft-tissue (e.g. brain); (2) Billions don't have access due to cost or safety issues; (3) metal will heat/move in high magnetic fields; (4) Millions of cases of traumatic brain injury in US alone; (5) even more of non-traumatic brain injury; (6) (e.g. stroke, infection, chemical exposure); (7) Need for early diagnostic; (8) 'Signature' wound of recent conflicts; (9) 22% of injuries; (10) Implications for post-traumatic stress disorder; and (11) chronic traumatic encephalopathy.

  14. AMERICAN INNOVATION:MANUFACTURING LOW CARBON TECHNOLOGIES IN THE MIDWEST JANUARY 2010

    E-Print Network [OSTI]

    Hoffman, Andrew J.

    AMERICAN INNOVATION:MANUFACTURING LOW CARBON TECHNOLOGIES IN THE MIDWEST JANUARY 2010 F R E D E R I by The Energy Foundation and the RE-AMP Global Warming Strategic Action Fund. The Climate Group would also like Hannon, Midwest Regional Manager, The Climate Group Acknowledgements We are grateful for the economic

  15. Impacts of Land Management on Agroecosystem Carbon Fluxes in the Upper Midwest, United States

    E-Print Network [OSTI]

    Minnesota, University of

    Impacts of Land Management on Agroecosystem Carbon Fluxes in the Upper Midwest, United States Investigators: T.J. Griffis and J.M. Baker Funding Source: United States Department of Energy, Office-soybean rotation systems located in the Upper Midwest. The management strategies will include: 1) Conventional corn

  16. KTFC Midwest Bible Radio Wind Farm | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are beingZealand Jump to: navigation, searchOf Kilauea Volcano, Hawaii |Island, Florida: EnergyKDOTII JumpKTFC Midwest

  17. MIE Regional Climate Change Impact Webinar Series: Midwest | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onYouTube YouTube Note: Since the.pdfBreaking ofOil & Gas »ofMarketing |Prepare For26,MICHIGANEnergy Midwest MIE

  18. Midwest Independent Transmission System Operator | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are beingZealand Jump to: navigation, searchOfRose BendMiasole Inc JumpMicroPlanet Name: Midwest Independent

  19. Midwest Renewable Energy Credits LLC | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are beingZealand Jump to: navigation, searchOfRose BendMiasole Inc JumpMicroPlanet Name: Midwest IndependentCredits LLC

  20. Midwest Energy Inc. Smart Grid Project | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directedAnnual SiteofEvaluatingGroup |JilinLu anMicrogreen Polymers Inc Jump to:JumpMidwest Energy Inc

  1. Midwest Independent Transmission System Operator Smart Grid Project | Open

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directedAnnual SiteofEvaluatingGroup |JilinLu anMicrogreen Polymers Inc Jump to:JumpMidwest Energy IncEnergy

  2. Midwest States Save Energy Now Partnership Program | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels Data Center Home Page onYouTube YouTube Note: Since the.pdfBreaking ofOil &315_ArnibanPriority DataPART 970Midwest Building Energy

  3. Implementation Study of Energy Conservation Recommendations in the Upper Midwest Region

    E-Print Network [OSTI]

    Heisinger, K. P.; Bassett, K.; Twedt, M. P.

    The South Dakota State University (SDSU) Industrial Energy Optimization Program (IEOP) and Energy Analysis and Diagnostic Center (EADC) program perform energy audits for industrial companies in the Upper Midwest region of the United States. Each...

  4. Midwest Interstate Compact on Low-Level Radioactive Waste (Multiple States)

    Broader source: Energy.gov [DOE]

    The Midwest Interstate Low-Level Radioactive Waste Compact is an agreement between the states of Indiana, Iowa, Minnesota, Missouri, Ohio, and Wisconsin that provides for the cooperative and safe...

  5. Coordination of Retail Demand Response with Midwest ISO Markets

    SciTech Connect (OSTI)

    Bharvirkar, Ranjit; Bharvirkar, Ranjit; Goldman, Charles; Heffner, Grayson; Sedano, Richard

    2008-05-27T23:59:59.000Z

    The Organization of Midwest ISO States (OMS) launched the Midwest Demand Resource Initiative (MWDRI) in 2007 to identify barriers to deploying demand response (DR) resources in the Midwest Independent System Operator (MISO) region and develop policies to overcome them. The MWDRI stakeholders decided that a useful initial activity would be to develop more detailed information on existing retail DR programs and dynamic pricing tariffs, program rules, and utility operating practices. This additional detail could then be used to assess any"seams issues" affecting coordination and integration of retail DR resources with MISO's wholesale markets. Working with state regulatory agencies, we conducted a detailed survey of existing DR programs, dynamic pricing tariffs, and their features in MISO states. Utilities were asked to provide information on advance notice requirements to customers, operational triggers used to call events (e.g. system emergencies, market conditions, local emergencies), use of these DR resources to meet planning reserves requirements, DR resource availability (e.g., seasonal, annual), participant incentive structures, and monitoring and verification (M&V) protocols. This report describes the results of this comprehensive survey and discusses policy implications for integrating legacy retail DR programs and dynamic pricing tariffs into organized wholesale markets. Survey responses from 37 MISO members and 4 non-members provided information on 141 DR programs and dynamic pricing tariffs with a peak load reduction potential of 4,727 MW of retail DR resource. Major findings of this study area:- About 72percent of available DR is from interruptible rate tariffs offered to large commercial and industrial customers, while direct load control (DLC) programs account for ~;;18percent. Almost 90percent of the DR resources included in this survey are provided by investor-owned utilities. - Approximately, 90percent of the DR resources are available with less than two hours advance notice and over 1,900 MW can be dispatched on less than thirty minutes notice. These legacy DR programs are increasingly used by utilities for economic in addition to reliability purposes, with over two-thirds (68percent) of these programs callable based on market conditions. - Approximately 60percent of DLC programs and 30percent of interruptible rate programs called ten or more DR events in 2006. Despite the high frequency of DR events, customer complaints remained low. The use of economic criteria to trigger DR events and the flexibility to trigger a large number of events suggests that DR resources can help improve the efficiency of MISO wholesale markets. - Most legacy DR programs offered a reservation payment ($/kW) for participation; incentive payment levels averaged about $5/kW-month for interruptible rate tariffs and $6/kW-month for DLC programs. Few programs offered incentive payments that were explicitly linked to actual load reductions during events and at least 27 DR programs do not have penalties for non-performance. - Measurement and verification (M&V) protocols to estimate load impacts vary significantly across MISO states. Almost half of the DR programs have not been evaluated in recent times and thus performance data for DR events is not available. For many DLC programs, M&V protocols may need to be enhancedin order to allow participation in MISO's proposed EDR schedule. System operators and planners will need to develop more accurate estimates of the load reduced capability and actual performance.

  6. Practices and Processes of Leading High Performance Home Builders in the Upper Midwest

    SciTech Connect (OSTI)

    Von Thoma, E.; Ojczyk, C.

    2012-12-01T23:59:59.000Z

    The NorthernSTAR Building America Partnership team proposed this study to gain insight into the business, sales, and construction processes of successful high performance builders. The knowledge gained by understanding the high performance strategies used by individual builders, as well as the process each followed to move from traditional builder to high performance builder, will be beneficial in proposing more in-depth research to yield specific action items to assist the industry at large transform to high performance new home construction. This investigation identified the best practices of three successful high performance builders in the upper Midwest. In-depth field analysis of the performance levels of their homes, their business models, and their strategies for market acceptance were explored. All three builders commonly seek ENERGY STAR certification on their homes and implement strategies that would allow them to meet the requirements for the Building America Builders Challenge program. Their desire for continuous improvement, willingness to seek outside assistance, and ambition to be leaders in their field are common themes. Problem solving to overcome challenges was accepted as part of doing business. It was concluded that crossing the gap from code-based building to high performance based building was a natural evolution for these leading builders.

  7. Threatened and endangered fish and wildlife of the midwest

    SciTech Connect (OSTI)

    Schafer, D.W.; Robeck, K.E.

    1980-06-01T23:59:59.000Z

    This report contains information of federally-listed endangered and/or threatened fish and wildlife occurring in the midwestern states of Illinois, Indiana, Iowa, Kansas, Michigan, Minnesota, Missouri, Nebraska, Ohio, and Wisconsin. The information was compiled as a support document for the Regional Issue Identification and Assessment (RIIA) project sponsored by the Regional Assessments Division of the Office of Technology Impacts within the Department of Energy. The information on midwestern endangered species distribution, habitats, and reasons for population decline included in this document are designed to help assess the potential for adverse impacts if energy activities are sited within the general range of an endangered species. It is hoped that this document will thereby enhance the reliability of one portion of energy-related assessments performed in the Midwest. This report considers only those species listed prior to October 1979 as endangered and/or threatened in the federal endangered species list published in the Federal Register and that have been known to occur in the region in the last 20 years.

  8. MRI: Acquisition of a computing cluster for nuclear physics and astrophysics research at the University of Richmond

    E-Print Network [OSTI]

    Gilfoyle, Jerry

    the NSF at Richmond. He has been the manager of that project since then. That existing system is near Impact of Project on Teaching and Research 13 6 Project Management Plans 14 7 Dissemination Plan 15 8 support from the US Department of Energy (DOE) (Gilfoyle in nuclear physics) and the National Science

  9. AMERICAN INNOVATION:MANUFACTURING LOW CARBON TECHNOLOGIES IN THE MIDWEST EXECUTIVE SUMMARY

    E-Print Network [OSTI]

    Hoffman, Andrew J.

    the manufacture of hundreds of additional low-carbon technologies not examined in this report, and opportunitiesAMERICAN INNOVATION:MANUFACTURING LOW CARBON TECHNOLOGIES IN THE MIDWEST EXECUTIVE SUMMARY JANUARY substantial energy efficiency savings, new jobs created outside of the manufacturing sector, benefits from

  10. Switchgrass Biomass Production in the Midwest USA: Harvest and Nitrogen Management

    E-Print Network [OSTI]

    Laughlin, Robert B.

    Switchgrass Biomass Production in the Midwest USA: Harvest and Nitrogen Management Kenneth P. Vogel.,for switchgrass (Panicum virgatum L.) grown as a biomass or bioen- 1998; Brejda, 2000; Muir et al., 2001). The N and N rates for biomass produc- ment of switchgrass used for hay or grazing largely de- tion

  11. Stream Restoration in the Upper Midwest, U.S.A. Gretchen G. Alexander1

    E-Print Network [OSTI]

    Allan, David

    Stream Restoration in the Upper Midwest, U.S.A. Gretchen G. Alexander1 and J. David Allan1,2 Abstract Restoration activities intended to improve the condition of streams and rivers are widespread types of activities and their effectiveness. We developed a database of 1,345 stream restoration

  12. Nuclear Instruments and Methods in Physics Research A 571 (2007) 102105 Preliminary studies of a simultaneous PET/MRI scanner based on the

    E-Print Network [OSTI]

    of a simultaneous PET/MRI scanner based on the RatCAP small animal tomograph C. Woodya,Ã?, D. Schlyera , P. Vaskaa data using positron emission tomography (PET). The approach is based on the technology used for the RatCAP conscious small animal PET tomograph which utilizes block detectors consisting of pixelated arrays of LSO

  13. The contribution of future agricultural trends in the US Midwest to global climate change mitigation

    SciTech Connect (OSTI)

    Thomson, Allison M.; Kyle, G. Page; Zhang, Xuesong; Bandaru, Varaprasad; West, Tristram O.; Wise, Marshall A.; Izaurralde, Roberto C.; Calvin, Katherine V.

    2014-01-19T23:59:59.000Z

    Land use change is a complex response to changing environmental and socioeconomic systems. Historical drivers of land use change include changes in the natural resource availability of a region, changes in economic conditions for production of certain products and changing policies. Most recently, introduction of policy incentives for biofuel production have influenced land use change in the US Midwest, leading to concerns that bioenergy production systems may compete with food production and land conservation. Here we explore how land use may be impacted by future climate mitigation measures by nesting a high resolution agricultural model (EPIC – Environmental Policy Indicator Climate) for the US Midwest within a global integrated assessment model (GCAM – Global Change Assessment Model). This approach is designed to provide greater spatial resolution and detailed agricultural practice information by focusing on the climate mitigation potential of agriculture and land use in a specific region, while retaining the global economic context necessary to understand the far ranging effects of climate mitigation targets. We find that until the simulated carbon prices are very high, the US Midwest has a comparative advantage in producing traditional food and feed crops over bioenergy crops. Overall, the model responds to multiple pressures by adopting a mix of future responses. We also find that the GCAM model is capable of simulations at multiple spatial scales and agricultural technology resolution, which provides the capability to examine regional response to global policy and economic conditions in the context of climate mitigation.

  14. Reconstruction algorithms for MRI

    E-Print Network [OSTI]

    Bilgic?, Berkin

    2013-01-01T23:59:59.000Z

    This dissertation presents image reconstruction algorithms for Magnetic Resonance Imaging (MRI) that aims to increase the imaging efficiency. Algorithms that reduce imaging time without sacrificing the image quality and ...

  15. What Will the 2014 Farm Bill Mean for Midwest Agriculture?

    E-Print Network [OSTI]

    (6%). All other programs such as trade, credit, rural development and Extension and research a misnomer since the majority of the spending is not directed toward production agriculture. The long bill outlays. The 2008 farm bill was projected to have about seventy percent of spending dedicated

  16. Improvements in Low Field MRI

    E-Print Network [OSTI]

    Ogier, Stephen E

    2013-02-01T23:59:59.000Z

    The world of clinical magnetic resonance imaging (MRI) is presently dominated by multi-million dollar machines that use large superconducting magnets to generate very high quality images. It is possible to perform MRI at lower magnetic field...

  17. DOE - Office of Legacy Management -- Midwest Manufacturing Co - IL 0-04

    Office of Legacy Management (LM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOn AprilA group currentBradleyTableSelling Corp - CT 0-01 FUSRAP ConsideredMill SiteMidwest

  18. SU-E-J-239: IMRT Planning of Prostate Cancer for a MRI-Linac Based On MRI Only

    SciTech Connect (OSTI)

    Chen, X; Prior, P; Paulson, E; Lawton, C; Li, X [Medical College of Wisconsin, Milwaukee, WI (United States)

    2014-06-01T23:59:59.000Z

    Purpose: : To investigate dosimetric differences between MRI- and CT-based IMRT planning for prostate cancer, the impact of a magnetic field in a MRI-Linac, and to explore the feasibility of IMRT planning based on MRI alone. Methods: IMRT plans were generated based on CT and MRI images acquired on two representative prostate-cancer patients using clinical dose volume constraints. A research planning system (Monaco, Elekta), which employs a Monte Carlo dose engine and includes a perpendicular magnetic field of 1.5T from an MRI-Linac, was used. Bulk electron density assignments based on organ-specific values from ICRU 46 were used to convert MRI (T2) to pseudo CT. With the same beam configuration as in the original CT plan, 5 additional plans were generated based on CT or MRI, with or without optimization (i.e., just recalculation) and with or without the magnetic field. The plan quality in terms of commonly used dose volume (DV) parameters for all plans was compared. The statistical uncertainty on dose was < 1%. Results: For plans with the same contour set but without re-optimization, the DV parameters were different from those for the original CT plan, mostly less than 5% with a few exceptions. These differences were reduced to mostly less than 3% when the plans were re-optimized. For plans with contours from MRI, the differences in the DV parameters varied depending on the difference in the contours as compared to CT. For the optimized plans with contours from MR, the differences for PTV were less than 3%. Conclusion: The prostate IMRT plans based on MRI-only for a MR-Linac were practically similar as compared to the CT plan under the same beam and optimization configuration if the difference on the structure delineation is excluded, indicating the feasibility of using MRI-only for prostate IMRT.

  19. Development Of Sustainable Biobased Products And Bioenergy In Cooperation With The Midwest Consortium For Sustainable Biobased Products And Energy

    SciTech Connect (OSTI)

    Michael Ladisch; Randy Woodson

    2009-03-18T23:59:59.000Z

    Collaborative efforts of Midwest Consortium have been put forth to add value to distiller's grains by further processing them into fermentable sugars, ethanol, and a protein rich co-product consistent with a pathway to a biorenewables industry (Schell et al, 2008). These studies were recently published in the enclosed special edition (Volume 99, Issue 12) of Bioresource Technology journal. Part of them have demonstrated the utilization of distillers grains as additional feedstock for increased ethanol production in the current dry grind process (Kim et al., 2008a, b; Dien et al.,2008, Ladisch et al., 2008a, b). Results showed that both liquid hot water (LHW) pretreatment and ammonia fiber expansion (AFEX) were effective for enhancing digestibility of distiller's grains. Enzymatic digestion of distiller's grains resulted in more than 90% glucose yield under standard assay conditions, although the yield tends to drop as the concentration of dry solids increases. Simulated process mass balances estimated that hydrolysis and fermentation of distillers grains can increase the ethanol yield by 14% in the current dry milling process (Kim et al., 2008c). Resulting co-products from the modified process are richer in protein and oil contents than conventional distiller's grains, as determined both experimentally and computationally. Other research topics in the special edition include water solubilization of DDGS by transesterification reaction with phosphite esters (Oshel el al., 2008) to improve reactivity of the DDGS to enzymes, hydrolysis of soluble oligomers derived from DDGS using functionalized mesoporous solid catalysts (Bootsma et al., 2008), and ABE (acetone, butanol, ethanol) production from DDGS by solventogenic Clostridia (Ezeji and Blaschek, 2008). Economic analysis of a modified dry milling process, where the fiber and residual starch is extracted and fermented to produce more ethanol from the distillers grains while producing highly concentrated protein co-product, has shown that the process is economically viable resulting in an increase in net present value (Perkis et al., 2008). According to the study, the revenue is expected to increase further with improved amino acid profile of the protein rich co-products and lower cost of cellulase enzyme mixture. Also, Kim and Dale (2008) discuss using life cycle analysis to enhance the environmental performance of the corn based ethanol. On the second phase of the research, concerted efforts were directed on assessing compositional variability of dry milling co-products collected from 4 different dry grind ethanol plants has been measured and its effect on enzymatic digestibility and fermentability. Fermentation utilized a recombinant glucose/xylose co-fermenting yeast (Saccharomyces cerevisiae 424A (LNH-ST)). No significant compositional variability among the samples was found. Simultaneous saccharification and glucose/xylose co-fermentation of the pretreated distillers grains at solids and cellulase loadings of 150 g dry solids per liter and 6.4 mg protein per g dry substrate, respectively, yielded 74-801% of theoretical maximum ethanol concentration using recombinant Saccharomyces cerevisiae 424A (LNH-ST). The paper summarizing the results from the second phase of the Midwest Consortium is currently submitted to Bioresource Technology journal. The copy of the paper submitted is enclosed.

  20. Impacts of a nuclear war in South Asia on soybean and maize production in the Midwest United States

    E-Print Network [OSTI]

    Robock, Alan

    Impacts of a nuclear war in South Asia on soybean and maize production in the Midwest United States conditions from war-related smoke. We combined observed climate conditions for the states of Iowa, Illinois phases also had an important effect. 1 Introduction In the event of nuclear war, targets in cities

  1. Impacts of a nuclear war in South Asia on soybean and maize production in the Midwest United States

    E-Print Network [OSTI]

    Robock, Alan

    Impacts of a nuclear war in South Asia on soybean and maize production in the Midwest United States and soybeans to cooler, drier, and darker conditions from war-related smoke. We combined observed climate had an important effect. 1 Introduction In the event of nuclear war, targets in cities and industrial

  2. Fuel-Cycle Fossil Energy Use and Greenhouse Gas Emissions of Fuel Ethanol Produced from U.S. Midwest Corn

    E-Print Network [OSTI]

    Patzek, Tadeusz W.

    #12;Fuel-Cycle Fossil Energy Use and Greenhouse Gas Emissions of Fuel Ethanol Produced from U on a mass emission per travel mile basis, the corn-to-ethanol fuel cycle for Midwest-produced ethanol% of total domestic ethanol production. That is, while the model still covers all alternative fuels and five

  3. MIDWEST ISO CO-OPTIMIZATION BASED REAL-TIME DISPATCH AND PRICING OF ENERGY AND ANCILLARY SERVICES

    E-Print Network [OSTI]

    Tesfatsion, Leigh

    day-ahead counterpart, real-time locational marginal prices (LMP) are calculated every fiveMIDWEST ISO CO-OPTIMIZATION BASED REAL-TIME DISPATCH AND PRICING OF ENERGY AND ANCILLARY SERVICES-time dispatch and pricing. The RT SCED formulation at the core of the real-time dispatch and pricing market

  4. University of Michigan, EECS, Ann Arbor The Midwest Computer Vision Workshop (MCVW) 2011 is an informal meeting of academic and

    E-Print Network [OSTI]

    Eustice, Ryan

    May 5th & 6th , 2010 University of Michigan, EECS, Ann Arbor The Midwest Computer Vision Workshop will be presented. Steering Comittee: Silvio Savarese, University of Michigan Derek Hoiem, University of Illinois Technological Institute at Chicago Local organizers Silvio Savarese, University of Michigan Byung-Soo Kim

  5. to the Midwest Regional Center of Excellence for Biodefense and Emerging Infectious Disease Research

    E-Print Network [OSTI]

    Saleska, Scott

    ,4 Marilyn J. Roossinck1 * A mutualistic association between a fungal endophyte and a tropical panic grass­8). However, the effect of mycoviruses on mutualistic fungal endophytes is unknown. There is only one report of a mycovirus from the well- known mutualistic endophyte, Epichloë festucae, but no phenotype has been

  6. Accepted for presentation at the 45th Midwest Symposium on Circuits and Systems, August 4-7, 2002, Tulsa, Oklahoma. Copyright IEEE 2002

    E-Print Network [OSTI]

    , Tulsa, Oklahoma. Copyright IEEE 2002 NONLINEAR RECONSTRUCTION OF OVER-SAMPLED COARSELY QUANTIZED SIGNALS Midwest Symposium on Circuits and Systems, August 4-7, 2002, Tulsa, Oklahoma. Copyright IEEE 2002

  7. Relationship to CCEFP strategy ! MRI Compatible Robot with an Active Cannula!

    E-Print Network [OSTI]

    Webster III, Robert James

    construction cost, zero maintenance) Test bed to the center: MRI scanners (3 at Vanderbilt and one at Georgia invasiveness. " " " " " · Constructed first (non-MRI compatible) prototype · Prototype construction underway.c.cardona@vanderbilt.edu http://research.vuse.vanderbilt.edu/MEDLab/index.htm ! Motivation! Challenges! · Must use components

  8. An fMRI study of multimodal semantic and phonological processing in reading disabled adolescents

    E-Print Network [OSTI]

    2009 /Accepted: 11 September 2009 # The International Dyslexia Association 2009 Abstract Using Dyslexia . fMRI . Performance . Phonology. Reading disability. Semantics Introduction The neurobiology of reading disability An increasing body of research suggests that the core deficit in developmental dyslexia

  9. MRI Beginnings - a Legacy | GE Global Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Legacy From Nobel Ideas to Industrial Success - Bill Edelstein's Legacy Scott Smith 2014.06.13 Edelsteinwith-MRmachine Nuclear magnetic resonance (NMR) was discovered in...

  10. MRI Beginnings - a Legacy | GE Global Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Science (SC)Integrated Codes |IsLove Your Home and It'll Love YouTokamak |MPC Equipment The

  11. Brain MRI Classification using the Expectation Maximization

    E-Print Network [OSTI]

    Chen, Tsuhan

    Brain MRI Classification using the Expectation Maximization made a brain magnetic resonance image (MRI) classification algorithm that uses a twostage applied to a set of normal brain MR images for further testing. We accomplished a working

  12. A pulsed electromagnet controller for prepolarized MRI

    E-Print Network [OSTI]

    Nam, Hyokwon

    2001-01-01T23:59:59.000Z

    Magnetic resonance imaging (MRI) is a popular medical imaging modality that provides high resolution images with superior contrast. Conventional MRI systems rely on large magnets to generate the main magnetic field, B?, that is both strong...

  13. The potential impacts of a competitive wholesale market in the midwest: A preliminary examination of centralized dispatch

    SciTech Connect (OSTI)

    Lesieutre, Bernard C.; Bartholomew, Emily; Eto, Joseph H.; Hale, Douglas; Luong, Thanh

    2004-07-01T23:59:59.000Z

    In March 2005, the Midwest Independent System Operator (MISO) will begin operating the first-ever wholesale market for electricity in the central and upper Midwestern portion of the United States. Region-wide, centralized, security-constrained, bid-based dispatch will replace the current system of decentralized dispatch by individual utilities and control areas. This report focuses on how the operation of generators may change under centralized dispatch. We analyze a stylized example of these changes by comparing a base case dispatch based on a ''snapshot'' taken from MISO's state estimator for an actual, historical dispatch (4 p.m., July 7, 2003) to a hypothetical, centralized dispatch that seeks to minimize the total system cost of production, using estimated cost data collected by the EIA. Based on these changes in dispatch, we calculate locational marginal prices, which in turn reveals the location of congestion within MISO's footprint, as well as the distribution of congestion revenues. We also consider two sensitivity scenarios that examine (1) the effect of changes in MISO membership (2003 vs. 2004 membership lists), and (2) different load and electrical data, based on a snapshot from a different date and time (1 p.m., Feb. 18, 2004). Although our analysis offers important insights into how the MISO market could operate when it opens, we do not address the question of the total benefits or costs of creating a wholesale market in the Midwest.

  14. Fuel ethanol produced from U.S. Midwest corn : help or hindrance to the vision of Kyoto?

    SciTech Connect (OSTI)

    Wang, M.; Saricks, C.; Wu, M.; Energy Systems

    1999-07-01T23:59:59.000Z

    In this study, we examined the role of corn-feedstock ethanol in reducing greenhouse gas (GHG) emissions, given present and near-future technology and practice for corn farming and ethanol production. We analyzed the full-fuel-cycle GHG effects of corn-based ethanol using updated information on corn operations in the upper Midwest and existing ethanol production technologies. Information was obtained from representatives of the U.S. Department of Agriculture, faculty of midwestern universities with expertise in corn production and animal feed, and acknowledged authorities in the field of ethanol plant engineering, design, and operations. Cases examined included use of E85 (85% ethanol and 15% gasoline by volume) and E10 (10% ethanol and 90% gasoline). Among key findings is that Midwest-produced ethanol outperforms conventional (current) and reformulated (future) gasoline with respect to energy use and GHG emissions (on a mass emission per travel mile basis). The superiority of the energy and GHG results is well outside the range of model noise. An important facet of this work has been conducting sensitivity analyses. These analyses let us rank the factors in the corn-to-ethanol cycle that are most important for limiting GHG generation. These rankings could help ensure that efforts to reduce that generation are targeted more effectively.

  15. Improvements in Low Field MRI 

    E-Print Network [OSTI]

    Ogier, Stephen E

    2013-02-01T23:59:59.000Z

    previously developed a desktop MRI system, but the receiver was not phase stable. By digitizing the second RF pulse in the pulse sequence, it is possible to extract information about system delays to correct for phase shifts, rendering the system phase stable...

  16. The 1999 Midwest Symposium on Circuits and Systems, New Mexico State University, Aug. 1999 Random-Process Formulation of Computationally Efficient

    E-Print Network [OSTI]

    Vanderbei, Robert J.

    The 1999 Midwest Symposium on Circuits and Systems, New Mexico State University, Aug. 1999 Random formulation of design con- straints in such an optimization setting and illustrates the concepts through dimensions of an approach developed earlier for the design of FIR digital filters in one dimension [4

  17. TransForumNews from Argonne's Transportation Research Program www.transportation.anl.gov

    E-Print Network [OSTI]

    Kemner, Ken

    page 10 A revolutionary advance in our understanding of how diesel engines work may unlock new at the local and regional level. 16 How Might Increased Biofuel Production Affect Midwest Water Supplies.S. Department of Energy's Advanced Research Projects Agency-Energy (ARPA-E), a government agency that funds

  18. Magnetic Resonance Imaging (MRI) of PEM Dehydration and Gas Manifold...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Resonance Imaging (MRI) of PEM Dehydration and Gas Manifold Flooding During Continuous Fuel Cell Operation. Magnetic Resonance Imaging (MRI) of PEM Dehydration and Gas Manifold...

  19. MRI Ventures | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov YouKizildere I Geothermal Pwer Plant Jump to:LandownersLuther, Oklahoma:EnergyECO Auger <SmarTurbineMIT-MRI Ventures

  20. Developing a Portfolio of Sustainable Bioenergy Feedstock Production Systems for the US Midwest: A Research and Demonstration Project

    E-Print Network [OSTI]

    Debinski, Diane M.

    a growing portion of our bioenergy feedstocks. While such second generation feedstocks show numerous on fossil fuels. In response, the demand for feedstocks for liquid biofuels will continue to grow

  1. Developing a Portfolio of Sustainable Bioenergy Feedstock Production Systems for the US Midwest: A Research and Demonstration Project

    E-Print Network [OSTI]

    Jager, Henriette I.

    a growing portion of our bioenergy feedstocks. While such "second generation" feedstocks show numerous on fossil fuels. In response, the demand for feedstocks for liquid biofuels will continue to grow

  2. NMR, MRI, and spectroscopic MRI in inhomogeneous fields

    DOE Patents [OSTI]

    Demas, Vasiliki; Pines, Alexander; Martin, Rachel W; Franck, John; Reimer, Jeffrey A

    2013-12-24T23:59:59.000Z

    A method for locally creating effectively homogeneous or "clean" magnetic field gradients (of high uniformity) for imaging (with NMR, MRI, or spectroscopic MRI) both in in-situ and ex-situ systems with high degrees of inhomogeneous field strength. THe method of imaging comprises: a) providing a functional approximation of an inhomogeneous static magnetic field strength B.sub.0({right arrow over (r)}) at a spatial position {right arrow over (r)}; b) providing a temporal functional approximation of {right arrow over (G)}.sub.shim(t) with i basis functions and j variables for each basis function, resulting in v.sub.ij variables; c) providing a measured value .OMEGA., which is an temporally accumulated dephasing due to the inhomogeneities of B.sub.0({right arrow over(r)}); and d) minimizing a difference in the local dephasing angle .phi.({right arrow over (r)},t)=.gamma..intg..sub.0.sup.t{square root over (|{right arrow over (B)}.sub.1({right arrow over (r)},t')|.sup.2+({right arrow over (r)}{right arrow over (G)}.sub.shimG.sub.shim(t')+.parallel.{right arrow over (B)}.sub.0({right arrow over (r)}).parallel..DELTA..omega.({right arrow over (r)},t'/.gamma/).sup.2)}dt'-.OMEGA. by varying the v.sub.ij variables to form a set of minimized v.sub.ij variables. The method requires calibration of the static fields prior to minimization, but may thereafter be implemented without such calibration, may be used in open or closed systems, and potentially portable systems.

  3. Research | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    membrane proteins. As part of their mandates, the Midwest Center for Structural Genomics (MCSG), the Center of Structural Genomics of Infectious Diseases (CSGID), and the...

  4. Combined PET/MRI scanner

    DOE Patents [OSTI]

    Schlyer, David (Bellport, NY); Woody, Craig L. (Setauket, NY); Rooney, William (Miller Place, NY); Vaska, Paul (Sound Beach, NY); Stoll, Sean (Wading River, NY); Pratte, Jean-Francois (Stony Brook, NY); O'Connor, Paul (Bellport, NY)

    2007-10-23T23:59:59.000Z

    A combined PET/MRI scanner generally includes a magnet for producing a magnetic field suitable for magnetic resonance imaging, a radiofrequency (RF) coil disposed within the magnetic field produced by the magnet and a ring tomograph disposed within the magnetic field produced by the magnet. The ring tomograph includes a scintillator layer for outputting at least one photon in response to an annihilation event, a detection array coupled to the scintillator layer for detecting the at least one photon outputted by the scintillator layer and for outputting a detection signal in response to the detected photon and a front-end electronic array coupled to the detection array for receiving the detection signal, wherein the front-end array has a preamplifier and a shaper network for conditioning the detection signal.

  5. Challenges for molecular neuroimaging with MRI

    E-Print Network [OSTI]

    Lelyveld, Victor S.

    Magnetic resonance (MRI)-based molecular imaging methods are beginning to have impact in neuroscience. A growing number of molecular imaging agents have been synthesized and tested in vitro, but so far relatively few have ...

  6. Proceedings of Midwest Artificial Intelligence and Cognitive Science Society Conference, Dayton, 1998, pp. 124-131.

    E-Print Network [OSTI]

    , 1998, pp. 124-131. 1 RELATIONSHIP BETWEEN TUTORIAL GOALS AND SENTENCE STRUCTURE IN A CORPUS OF TUTORING tutorial goal structure. In this paper we analyze clusters of sentences serving the same tutorial goal. We by the Cognitive Science Program, Office of Naval Research under Grant No. N000149410338 to Illinois Institute

  7. Comparison of MRI-based and CT/MRI fusion-based postimplant dosimetric analysis of prostate brachytherapy

    SciTech Connect (OSTI)

    Tanaka, Osamu [Department of Radiology, Gifu University School of Medicine, Gifu City (Japan)]. E-mail: osa-mu@umin.ac.jp; Hayashi, Shinya [Department of Radiology, Gifu University School of Medicine, Gifu City (Japan); Matsuo, Masayuki [Department of Radiology, Gifu University School of Medicine, Gifu City (Japan); Sakurai, Kota [Department of Radiology, Gifu University School of Medicine, Gifu City (Japan); Department of Urology, Gifu University School of Medicine, Gifu City (Japan); Nakano, Masahiro [Department of Urology, Gifu University School of Medicine, Gifu City (Japan); Maeda, Sunaho [Department of Radiology, Gifu University School of Medicine, Gifu City (Japan); Kajita, Kimihiro R.T. [Department of Radiology, Gifu University School of Medicine, Gifu City (Japan); Deguchi, Takashi [Department of Urology, Gifu University School of Medicine, Gifu City (Japan); Hoshi, Hiroaki [Department of Radiology, Gifu University School of Medicine, Gifu City (Japan)

    2006-10-01T23:59:59.000Z

    Purpose: The aim of this study was to compare the outcomes between magnetic resonance imaging (MRI)-based and computed tomography (CT)/MRI fusion-based postimplant dosimetry methods in permanent prostate brachytherapy. Methods and Materials: Between October 2004 and March 2006, a total of 52 consecutive patients with prostate cancer were treated by brachytherapy, and postimplant dosimetry was performed using CT/MRI fusion. The accuracy and reproducibility were prospectively compared between MRI-based dosimetry and CT/MRI fusion-based dosimetry based on the dose-volume histogram (DVH) related parameters as recommended by the American Brachytherapy Society. Results: The prostate volume was 15.97 {+-} 6.17 cc (mean {+-} SD) in MRI-based dosimetry, and 15.97 {+-} 6.02 cc in CT/MRI fusion-based dosimetry without statistical difference. The prostate V100 was 94.5% and 93.0% in MRI-based and CT/MRI fusion-based dosimetry, respectively, and the difference was statistically significant (p = 0.002). The prostate D90 was 119.4% and 114.4% in MRI-based and CT/MRI fusion-based dosimetry, respectively, and the difference was statistically significant (p = 0.004). Conclusion: Our current results suggested that, as with fusion images, MR images allowed accurate contouring of the organs, but they tended to overestimate the analysis of postimplant dosimetry in comparison to CT/MRI fusion images. Although this MRI-based dosimetric discrepancy was negligible, MRI-based dosimetry was acceptable and reproducible in comparison to CT-based dosimetry, because the difference between MRI-based and CT/MRI fusion-based results was smaller than that between CT-based and CT/MRI fusion-based results as previously reported.

  8. application ultrafast mri: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Jeffrey A. 11 Applications of MRI in Fluidics: Single Echo Acquisition MRI Toward Microfluidics Texas A&M University - TxSpace Summary: (13,14). A handheld lab-on-a-chip may...

  9. Engineered metalloproteins as contrast sensors for molecular fMRI

    E-Print Network [OSTI]

    Lelyveld, Victor S

    2010-01-01T23:59:59.000Z

    Functional brain imaging technologies seek to expand our understanding of intact neural systems. Present day functional MRI (fMRI) measures the delayed hemodynamic response that is indirectly associated with neural activity. ...

  10. Physics of MRI Polytechnic University, Brooklyn, NY 11201

    E-Print Network [OSTI]

    Suel, Torsten

    than CT, more susceptible to patient motion CT MRI PET #12;EL582 MRI Physics Yao Wang, Polytechnic U structure (as with X-ray CT) · Provide high contrast between different soft tissues (X-ray CT cannot

  11. Design of an MRI compatible robot for wrist rehabilitation

    E-Print Network [OSTI]

    Mendelowitz, Sarah E. (Sarah Elizabeth), 1980-

    2005-01-01T23:59:59.000Z

    Magnetic Resonance Imaging (MRI) can be used to study the effects of robotic therapy on stroke patients. This thesis focuses on the design of an MRI compatible wrist robot to be used as a clinical tool for studying the ...

  12. One-way coupling of an integrated assessment model and a water resources model: evaluation and implications of future changes over the US Midwest

    SciTech Connect (OSTI)

    Voisin, Nathalie; Liu, Lu; Hejazi, Mohamad I.; Tesfa, Teklu K.; Li, Hongyi; Huang, Maoyi; Liu, Ying; Leung, Lai-Yung R.

    2013-11-18T23:59:59.000Z

    An integrated model is being developed to advance our understanding of the interactions between human activities, terrestrial system and water cycle, and how system interactions will be affected by a changing climate at the regional scale. As a first step towards that goal, a global integrated assessment model including a waterdemand model is coupled offline with a land surface hydrology – routing – water resources management model. A spatial and temporal disaggregation approach is developed to project the annual regional water demand simulations into a daily time step and subbasin representation. The model demonstrated reasonable ability to represent the historical flow regulation and water supply over the Midwest (Missouri, Upper Mississippi and Ohio). Implications for the future flow regulation, water supply and supply deficit are investigated using a climate change projection with the B1 emission scenario which affects both natural flow and water demand. Over the Midwest, changes in flow regulation are mostly driven by the change in natural flow due to the limited storage capacity over the Ohio and Upper Mississippi river basins. The changes in flow and demand have a combined effect on the Missouri Summer regulated flow. The supply deficit tends to be driven by the change in flow over the region. Spatial analysis demonstrates the relationship between the supply deficit and the change in demand over urban areas not along a main river or with limited storage, and over areas upstream of groundwater dependent fields with therefore overestimated demand.

  13. Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Scienceand Requirements Recently ApprovedReliabilityPrincipal Investigators PostdoctoralResearch

  14. Applications of MRI in Fluidics: Single Echo Acquisition MRI Toward Microfluidics

    E-Print Network [OSTI]

    Bosshard, John

    2006-08-16T23:59:59.000Z

    resonance imaging (MRI) to microscale fluid flow quantification. This is important because development and improvement of microfluidic devices requires the ability to accurately and non-invasively measure microscale flow. Lab-on-a-chip aims to integrate...

  15. Midwest Forensics Resource Center

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    HPRT and SRY) versus high molecular weight products (i.e. Amel-X and Amel-Y) that is diagnostic for an analyst in assessing the extent of degradation of nuclear DNA recovered...

  16. Midwest Energy Codes Project

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't YourTransport(FactDepartment3311,Official FileEnergy Midsize Wind Turbines for

  17. Midwest Forensics Resource Center

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Science (SC)Integrated Codes |IsLove Your1 SECTION A. Revised:7, at 3:00 Science Bowl5 2.862

  18. atypical mri features: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    al. (2004) found that patients treated with typical antipsychotics exhibited 2 3-D MRI Brain Scan Feature Classification Using an Oct-tree Representation Computer Technologies and...

  19. Ultra-low field MRI of prostate cancer using SQUID detection

    E-Print Network [OSTI]

    Busch, Sarah Elizabeth

    2011-01-01T23:59:59.000Z

    coil. Chapter 3 3 Ultra low field MRI 3.1 Polarization TheUltra-low field MRI of prostate cancer using SQUID detectionSteven Conolly Spring 2011 Ultra-low field MRI of prostate

  20. Cost Effective Open Geometry HTS MRI System amended to BSCCO 2212 Wire for High Field Magnets

    SciTech Connect (OSTI)

    Kennth Marken

    2006-08-11T23:59:59.000Z

    The original goal of this Phase II Superconductivity Partnership Initiative project was to build and operate a prototype Magnetic Resonance Imaging (MRI) system using high temperature superconductor (HTS) coils wound from continuously processed dip-coated BSCCO 2212 tape conductor. Using dip-coated tape, the plan was for MRI magnet coils to be wound to fit an established commercial open geometry, 0.2 Tesla permanent magnet system. New electronics and imaging software for a prototype higher field superconducting system would have added significantly to the cost. However, the use of the 0.2 T platform would allow the technical feasibility and the cost issues for HTS systems to be fully established. Also it would establish the energy efficiency and savings of HTS open MRI compared with resistive and permanent magnet systems. The commercial goal was an open geometry HTS MRI running at 0.5 T and 20 K. This low field open magnet was using resistive normal metal conductor and its heat loss was rather high around 15 kolwatts. It was expected that an HTS magnet would dissipate around 1 watt, significantly reduce power consumption. The SPI team assembled to achieve this goal was led by Oxford Instruments, Superconducting Technology (OST), who developed the method of producing commercial dip coated tape. Superconductive Components Inc. (SCI), a leading US supplier of HTS powders, supported the conductor optimization through powder optimization, scaling, and cost reduction. Oxford Magnet Technology (OMT), a joint venture between Oxford Instruments and Siemens and the world’s leading supplier of MRI magnet systems, was involved to design and build the HTS MRI magnet and cryogenics. Siemens Magnetic Resonance Division, a leading developer and supplier of complete MRI imaging systems, was expected to integrate the final system and perform imaging trials. The original MRI demonstration project was ended in July 2004 by mutual consent of Oxford Instruments and Siemens. Between the project start and that date a substantial shift in the MRI marketplace occurred, with rapid growth for systems at higher fields (1.5 T and above) and a consequent decline in the low field market (<1.0 T). While the project aim appeared technically attainable at that time, the conclusion was reached that the system and market economics do not warrant additional investment. The program was redirected to develop BSCCO 2212 multifilament wire development for high field superconducting magnets for NMR and other scientific research upon an agreement between DOE and Oxford Instruments, Superconducting Technology. The work t took place between September, 2004 and the project end in early 2006 was focused on 2212 multifilamentary wire. This report summarizes the technical achievements both in 2212 dip coated for an HTS MRI system and in BSCCO 2212 multifilamentary wire for high field magnets.

  1. HIGH RESOLUTION, MRI-BASED, SEGMENTED, COMPUTERIZED HEAD PHANTOM.

    E-Print Network [OSTI]

    Duncan, James S.

    was created from 124 transverse MRI images of a healthy normal. The transverse T2 slices, recorded in a 256x. Internal volumes compare favorably to those described in the ICRP Reference Man. Conclusion and improved. We have developed a voxel based head phantom by manually drawing contours on 124 transverse MRI

  2. Automatic Tissue Classification for the Human Head from Multispectral MRI

    E-Print Network [OSTI]

    Utah, University of

    1 Automatic Tissue Classification for the Human Head from Multispectral MRI Tolga Tasdizen, David for classifying multispectral MR scans of the human head into nine tissue classes. User initialization is adopted. #12;Chapter 1 Introduction Classification of head magnetic resonance imaging (MRI) data

  3. abnormal brain mri: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    abnormal brain mri First Page Previous Page 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 Next Page Last Page Topic Index 1 Improvement of MRI brain...

  4. Clinical Evaluation of Stereotactic Target Localization Using 3-Tesla MRI for Radiosurgery Planning

    SciTech Connect (OSTI)

    MacFadden, Derek [University of Toronto Faculty of Medicine, Toronto, ON (Canada); Zhang Beibei; Brock, Kristy K. [Radiation Medicine Program, Princess Margaret Hospital, University Health Network, Toronto, ON (Canada); Hodaie, Mojgan [Division of Neurosurgery, Toronto Western Hospital, Toronto, ON (Canada); Laperriere, Normand [Radiation Medicine Program, Princess Margaret Hospital, University Health Network, Toronto, ON (Canada); Department of Radiation Oncology, University of Toronto, Toronto, ON (Canada); Schwartz, Michael [Division of Neurosurgery, Toronto Western Hospital, Toronto, ON (Canada); Tsao, May [Department of Radiation Oncology, University of Toronto, Toronto, ON (Canada); Department of Radiation Oncology, Sunnybrook Regional Cancer Centre, Toronto, ON (Canada); Stainsby, Jeffrey [Applied Science Laboratories, GE Healthcare, Mississauga, ON (Canada); Lockwood, Gina [Radiation Medicine Program, Princess Margaret Hospital, University Health Network, Toronto, ON (Canada); Mikulis, David [Department of Medical Imaging, University Health Network, Toronto, ON (Canada); Menard, Cynthia, E-mail: cynthia.menard@rmp.uhn.on.c [Radiation Medicine Program, Princess Margaret Hospital, University Health Network, Toronto, ON (Canada); Department of Radiation Oncology, University of Toronto, Toronto, ON (Canada)

    2010-04-15T23:59:59.000Z

    Purpose: Increasing the magnetic resonance imaging (MRI) field strength can improve image resolution and quality, but concerns remain regarding the influence on geometric fidelity. The objectives of the present study were to spatially investigate the effect of 3-Tesla (3T) MRI on clinical target localization for stereotactic radiosurgery. Methods and Materials: A total of 39 patients were enrolled in a research ethics board-approved prospective clinical trial. Imaging (1.5T and 3T MRI and computed tomography) was performed after stereotactic frame placement. Stereotactic target localization at 1.5T vs. 3T was retrospectively analyzed in a representative cohort of patients with tumor (n = 4) and functional (n = 5) radiosurgical targets. The spatial congruency of the tumor gross target volumes was determined by the mean discrepancy between the average gross target volume surfaces at 1.5T and 3T. Reproducibility was assessed by the displacement from an averaged surface and volume congruency. Spatial congruency and the reproducibility of functional radiosurgical targets was determined by comparing the mean and standard deviation of the isocenter coordinates. Results: Overall, the mean absolute discrepancy across all patients was 0.67 mm (95% confidence interval, 0.51-0.83), significantly <1 mm (p < .010). No differences were found in the overall interuser target volume congruence (mean, 84% for 1.5T vs. 84% for 3T, p > .4), and the gross target volume surface mean displacements were similar within and between users. The overall average isocenter coordinate discrepancy for the functional targets at 1.5T and 3T was 0.33 mm (95% confidence interval, 0.20-0.48), with no patient-specific differences between the mean values (p >.2) or standard deviations (p >.1). Conclusion: Our results have provided clinically relevant evidence supporting the spatial validity of 3T MRI for use in stereotactic radiosurgery under the imaging conditions used.

  5. An RF dosimeter for independent SAR measurement in MRI scanners

    SciTech Connect (OSTI)

    Qian, Di; Bottomley, Paul A. [Division of MR Research, Department of Radiology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287 and Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, Maryland 21218 (United States)] [Division of MR Research, Department of Radiology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287 and Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, Maryland 21218 (United States); El-Sharkawy, AbdEl-Monem M.; Edelstein, William A., E-mail: w.edelstein@gmail.com [Division of MR Research, Department of Radiology, Johns Hopkins School of Medicine, Baltimore, Maryland 21287 (United States)

    2013-12-15T23:59:59.000Z

    Purpose: The monitoring and management of radio frequency (RF) exposure is critical for ensuring magnetic resonance imaging (MRI) safety. Commercial MRI scanners can overestimate specific absorption rates (SAR) and improperly restrict clinical MRI scans or the application of new MRI sequences, while underestimation of SAR can lead to tissue heating and thermal injury. Accurate scanner-independent RF dosimetry is essential for measuring actual exposure when SAR is critical for ensuring regulatory compliance and MRI safety, for establishing RF exposure while evaluating interventional leads and devices, and for routine MRI quality assessment by medical physicists. However, at present there are no scanner-independent SAR dosimeters. Methods: An SAR dosimeter with an RF transducer comprises two orthogonal, rectangular copper loops and a spherical MRI phantom. The transducer is placed in the magnet bore and calibrated to approximate the resistive loading of the scanner's whole-body birdcage RF coil for human subjects in Philips, GE and Siemens 3 tesla (3T) MRI scanners. The transducer loop reactances are adjusted to minimize interference with the transmit RF field (B{sub 1}) at the MRI frequency. Power from the RF transducer is sampled with a high dynamic range power monitor and recorded on a computer. The deposited power is calibrated and tested on eight different MRI scanners. Whole-body absorbed power vs weight and body mass index (BMI) is measured directly on 26 subjects. Results: A single linear calibration curve sufficed for RF dosimetry at 127.8 MHz on three different Philips and three GE 3T MRI scanners. An RF dosimeter operating at 123.2 MHz on two Siemens 3T scanners required a separate transducer and a slightly different calibration curve. Measurement accuracy was ?3%. With the torso landmarked at the xiphoid, human adult whole?body absorbed power varied approximately linearly with patient weight and BMI. This indicates that whole-body torso SAR is on average independent of the imaging subject, albeit with fluctuations. Conclusions: Our 3T RF dosimeter and transducers accurately measure RF exposure in body-equivalent loads and provide scanner-independent assessments of whole-body RF power deposition for establishing safety compliance useful for MRI sequence and device testing.

  6. NMR and MRI apparatus and method

    DOE Patents [OSTI]

    Clarke, John; Kelso, Nathan; Lee, SeungKyun; Moessle, Michael; Myers, Whittier; McDermott, Robert; ten Haken, Bernard; Pines, Alexander; Trabesinger, Andreas

    2007-03-06T23:59:59.000Z

    Nuclear magnetic resonance (NMR) signals are detected in microtesla fields. Prepolarization in millitesla fields is followed by detection with an untuned dc superconducting quantum interference device (SQUID) magnetometer. Because the sensitivity of the SQUID is frequency independent, both signal-to-noise ratio (SNR) and spectral resolution are enhanced by detecting the NMR signal in extremely low magnetic fields, where the NMR lines become very narrow even for grossly inhomogeneous measurement fields. Additional signal to noise benefits are obtained by use of a low noise polarization coil, comprising litz wire or superconducting materials. MRI in ultralow magnetic field is based on the NMR at ultralow fields. Gradient magnetic fields are applied, and images are constructed from the detected NMR signals.

  7. asl perfusion mri: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    high-resolution fMRI in the primate brain using a novel vertical large-bore 7 Tesla setup J. Pfeuffer1 Computer Technologies and Information Sciences Websites Summary:...

  8. IMMEDIATE JOB OPENING MRI technical developments and applications

    E-Print Network [OSTI]

    Duong, Timothy Q.

    ) the applications of these innovative imaging technologies to study anatomy, metabolism, physiology (such as blood + AC88 high performance gradient insert 6) MRI: 3T/90cm whole-body Philips Achieva There are also

  9. IMMEDIATE JOB OPENINGS MRI technical developments and applications

    E-Print Network [OSTI]

    Duong, Timothy Q.

    ) the applications of these innovative imaging technologies to study anatomy, metabolism, physiology (such as blood) MRI: 3T/90cm whole-body Siemens TIM Trio + AC88 high performance gradient insert, and 6) Access

  10. Simultaneous PET/fMRI for imaging neuroreceptor dynamics

    E-Print Network [OSTI]

    Sander, Christin Y. (Christin Yen-Ming)

    2014-01-01T23:59:59.000Z

    Whole-brain neuroimaging is a key technique for studying brain function and connectivity. Recent advances in combining two imaging modalities - magnetic resonance imaging (MRI) and positron emission tomography (PET) - into ...

  11. Comparing cropland net primary production estimates from inventory, a satellite-based model, and a process-based model in the Midwest of the United States

    SciTech Connect (OSTI)

    Li, Zhengpeng; Liu, Shuguang; Tan, Zhengxi; Bliss, N.; Young, Claudia J.; West, Tristram O.; Ogle, Stephen

    2014-05-06T23:59:59.000Z

    Accurately quantifying the spatial and temporal variability of net primary production (NPP) for croplands is essential to understand regional cropland carbon dynamics. We compared three NPP estimates for croplands in the Midwestern United States: inventory-based estimates using crop yield data from the U.S. Department of Agriculture (USDA) National Agricultural Statistics Service (NASS); estimates from the satellite-based Moderate Resolution Imaging Spectroradiometer (MODIS) NPP product; and estimates from the General Ensemble biogeochemical Modeling System (GEMS) process-based model. The three methods estimated mean NPP in the range of 469–687 g C m?2 yr?1 and total NPP in the range of 318–490 Tg C yr?1 for croplands in the Midwest in 2007 and 2008. The NPP estimates from crop yield data and the GEMS model showed the mean NPP for croplands was over 650 g C m?2 yr?1 while the MODIS NPP product estimated the mean NPP was less than 500 g C m?2 yr?1. MODIS NPP also showed very different spatial variability of the cropland NPP from the other two methods. We found these differences were mainly caused by the difference in the land cover data and the crop specific information used in the methods. Our study demonstrated that the detailed mapping of the temporal and spatial change of crop species is critical for estimating the spatial and temporal variability of cropland NPP. We suggest that high resolution land cover data with species–specific crop information should be used in satellite-based and process-based models to improve carbon estimates for croplands.

  12. Division of Clinical and Laboratory Investigation / Clinical Imagine Sciences Centre Research / Senior Radiographer Grade 7 (full time, permanent post)

    E-Print Network [OSTI]

    Jensen, Max

    Ref: 309 Division of Clinical and Laboratory Investigation / Clinical Imagine Sciences Centre provides an ideal opportunity to be involved in research and clinical MRI and PETCT at the Clinical Imaging and clinical trials. We also provide clinical services for PETCT and MRI memory assessment. You

  13. Mapping local hippocampal changes in Alzheimer's disease and normal ageing with MRI at 3 Tesla

    E-Print Network [OSTI]

    Thompson, Paul

    Mapping local hippocampal changes in Alzheimer's disease and normal ageing with MRI at 3 Tesla and Alzheimer's disease based on high resolution MRI at 3 Tesla. T1-weighted images were acquired from 19

  14. 3D He-3 diffusion MRI as a local in vivo morphometric tool to...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    He-3 diffusion MRI as a local in vivo morphometric tool to evaluate emphysematous rat lungs. 3D He-3 diffusion MRI as a local in vivo morphometric tool to evaluate emphysematous...

  15. High-resolution 7-Tesla fMRI of Human Hippocampal Subfields during Associative Learning.

    E-Print Network [OSTI]

    2014-01-01T23:59:59.000Z

    fMRI in the Human Brain at 7 Tesla: Combining Reduced Field-High-resolution 7-Tesla fMRI of Human Hippocampal Subfieldsrobustly using FMRI at 7 tesla. Journal of Neuroimaging, 23(

  16. WATER RESOURCES NEWS NEBRASKA WATER RESOURCES RESEARCH INSTITUTE

    E-Print Network [OSTI]

    Nebraska-Lincoln, University of

    , Northeast and Midwest areas of the n~tion. ~ . ".I.MeROVING HASLE. TREAT.MErlI A $1-1/4 million grant has

  17. SHEARING BOX SIMULATIONS OF THE MRI IN A COLLISIONLESS PLASMA Prateek Sharma and Gregory W. Hammett

    E-Print Network [OSTI]

    Hammett, Greg

    of the MRI in a collision- less plasma, focusing on local simulations in the shearing box limit. Quataert et

  18. BRIEF COMMUNICATION A 7 Tesla fMRI Study of Amygdala Responses to Fearful Faces

    E-Print Network [OSTI]

    Hadjikhani, Nouchine

    BRIEF COMMUNICATION A 7 Tesla fMRI Study of Amygdala Responses to Fearful Faces Wietske van der field strength. In this study, the feasibility of fMRI in the amygdalae at 7 Tesla was investigated in a fearful face depends on stimulus duration. Keywords Amygdala Á fMRI Á 7 Tesla Á Fear Á Face perception

  19. Efficient Concomitant and Remanence Field Artifact Reduction in Ultra-Low-Field MRI Using a

    E-Print Network [OSTI]

    Efficient Concomitant and Remanence Field Artifact Reduction in Ultra-Low-Field MRI Using: For ultra-low-field MRI, the spatial-encoding mag- netic fields generated by gradient coils can have strong to pre-polarize magnetization can improve the signal-to-noise ratio of ultra- low-field MRI. Yet

  20. Difficulties of T1 brain MRI segmentation techniques M S. Atkins*a

    E-Print Network [OSTI]

    Orchard, Jeffery J.

    : brain segmentation, T1-head MRI, IBSR data 1. INTRODUCTION We are interested in segmenting the brain in T1-weighted head scans to find the perimeter of the brain cortex, which is useful for functional MRI , is an automatic brain segmentation algorithm for MRI head scans. In the algorithm, a lower intensity threshold, t2

  1. Fluorine-19 MRI for Visualization and Quantification of Cell Migration in a Diabetes Model

    E-Print Network [OSTI]

    Laidlaw, David

    Fluorine-19 MRI for Visualization and Quantification of Cell Migration in a Diabetes Model Mangala the nonobese dia- betic mouse, an established model of type 1 diabetes, 19F MRI data were acquired showing Med 58: 725­734, 2007. © 2007 Wiley-Liss, Inc. Key words: T cells; diabetes; MRI; cell tracking

  2. Peptide functionalized superparamagnetic iron oxide nanoparticles as MRI contrast agents

    E-Print Network [OSTI]

    Atalar, Ergin

    of water molecules in different tissues create distinct signal intensities that enable detection of abnormal tissues.2 MRI uses radiofrequency in a magnetic field as source of radiation which has no harmful contrast. There are numerous types of contrast agents on the market and gadolinium (Gd3+ ) based CAs

  3. Analysis of Functional MRI Timeseries Data Using Signal Processing Techniques

    E-Print Network [OSTI]

    /39 #12;fMRI: The basic idea Experimental paradigm designed to activate neuronal metabolism Changes conjugate gradient Regularization parameter A found by crossvalidation strategy S. Chen ­ Final Exam optimization with conjugate gradient 0.5 s time resolution estimate from TR = 0.5 s dataset Supertemporal

  4. Bone motion analysis from dynamic MRI: acquisition and tracking

    E-Print Network [OSTI]

    Gilles, Benjamin

    overload, impingement or femoral head instability. For both the diagnosis and the surgical planningBone motion analysis from dynamic MRI: acquisition and tracking Benjamin Gilles1 , Rosalind Perrin2 methods in order to auto- matically extract active bone kinematics from multi-slice real-time dy- namic

  5. MRI Techniques for Noninvasive Monitoring of Transplanted Organs

    E-Print Network [OSTI]

    Moura, José

    (microimaging small animal mice, high resolution) ­ 2 Brucker Avance DRX (4.7 T and 7.0 T) MRI/MRS ­ Home the dynamic behavior of the transplanted organ Automatic segmentation of kidneys & their internal structures;12 Segmentation Algorithm Energy minimization by level set Identify the boundary of the cortex Preprocessing

  6. Wavelet smoothing of fMRI activation images Will Penny,

    E-Print Network [OSTI]

    Penny, Will

    Wavelet smoothing of fMRI activation images Will Penny, Wellcome Department of Imaging Neuroscience methods - such as wavelets. 100 #12;2 Wavelet Transform The wavelet spatial model is that introduced, a wavelet transform is defined in which an N-dimensional image is represented by an N-dimensional image

  7. UNSUPERVISED SEGMENTATION FOR AUTOMATIC DETECTION OF BRAIN TUMORS IN MRI

    E-Print Network [OSTI]

    Lefèvre, Sébastien

    a pre-segmentation to ex- tract the brain from the head. Then, a second segmentation is done insideUNSUPERVISED SEGMENTATION FOR AUTOMATIC DETECTION OF BRAIN TUMORS IN MRI A.S. Capelle, O. Alata, C- thod for magnetic resonance images. The aim of this seg- mentation is to divide the brain

  8. Evolution of the Midwest ISO

    E-Print Network [OSTI]

    Tesfatsion, Leigh

    -Transmission Owning Members Marketers · Allegheny Energy Supply · American Electric Power Co. · Automated Power Transmission System Operator, Inc. MAPP Fall Conference August 28, 2002 #12;Overview · General Background Information · MISO Today · MISO Evolution #12;General Background Information #12;General Utility Background

  9. 72nd Midwest PDE Seminar

    E-Print Network [OSTI]

    2013-11-14T23:59:59.000Z

    Nov 16, 2013 ... Stability of solutions to the dissipative quasi- ... Solitary water waves and their stability ... Hausdorff dimension and p-harmonic measure.

  10. MIDWEST ISO UPDATE Sherman Elliott

    E-Print Network [OSTI]

    Tesfatsion, Leigh

    power congestion through locational marginal pricing (LMP) energy market Long term regional transmission minutes · Manage congestion via Locational Marginal Pricing (LMP), Transmission Loading Relief (TLR reserve margin #12;9 MISO Market Operations Locational Marginal Pricing (LMP) based upon Security

  11. Midwest Numerical Analysis Day 2011

    E-Print Network [OSTI]

    by Car. From "South" to Purdue Union Club Hotel: Take I65-North, exit to St. Rd. 26-west;; Drive a few miles on Rd. 26, across the Wabash river, go up the hill to ...

  12. Midwest Numerical Analysis Day 2011

    E-Print Network [OSTI]

    May 7, 2011 ... Hybridizable Discontinuous Galerkin Methods for Elliptic Problems ... Department of Applied Mathematics, Illinois Institute of Technology ... Department of Computer Engineering & Informatics, University of Patras, Greece.

  13. Midwest Numerical Analysis Day 2011

    E-Print Network [OSTI]

    Pavel Bochev, Applied Mathematics and Applications, Sandia National Lab ... Such methods excel in controlling “structural” information losses responsible for the .... Efstratios Gallopoulos, Department of Computer Engineering & Informatics,

  14. MRI-compatible Haptics: Feasibility of using optical fiber Bragg grating strain-sensors to detect deflection of needles in an MRI environment

    E-Print Network [OSTI]

    Park, Yong-Lae

    MRI-compatible Haptics: Feasibility of using optical fiber Bragg grating strain-sensors to detect fiber-optic-based force and deflection sensors based on fiber Bragg grating (FBG) technology have been was developed using a single optical fiber and an MRI compatible biopsy needle (22ga x 15cm). The FBG sensor

  15. An Atlas-Based Electron Density Mapping Method for Magnetic Resonance Imaging (MRI)-Alone Treatment Planning and Adaptive MRI-Based Prostate Radiation Therapy

    SciTech Connect (OSTI)

    Dowling, Jason A., E-mail: jason.dowling@csiro.au [Australian e-Health Research Center, CSIRO ICT Commonwealth Scientific and Industrial Research Organisation Information and Communication Technologies Centre, Queensland (Australia); Lambert, Jonathan [Calvary Mater Newcastle Hospital, New South Wales (Australia); University of Newcastle, New South Wales (Australia); Parker, Joel [Calvary Mater Newcastle Hospital, New South Wales (Australia); Salvado, Olivier; Fripp, Jurgen [Australian e-Health Research Center, CSIRO ICT Commonwealth Scientific and Industrial Research Organisation Information and Communication Technologies Centre, Queensland (Australia); Capp, Anne; Wratten, Chris; Denham, James W.; Greer, Peter B. [Calvary Mater Newcastle Hospital, New South Wales (Australia); University of Newcastle, New South Wales (Australia)

    2012-05-01T23:59:59.000Z

    Purpose: Prostate radiation therapy dose planning directly on magnetic resonance imaging (MRI) scans would reduce costs and uncertainties due to multimodality image registration. Adaptive planning using a combined MRI-linear accelerator approach will also require dose calculations to be performed using MRI data. The aim of this work was to develop an atlas-based method to map realistic electron densities to MRI scans for dose calculations and digitally reconstructed radiograph (DRR) generation. Methods and Materials: Whole-pelvis MRI and CT scan data were collected from 39 prostate patients. Scans from 2 patients showed significantly different anatomy from that of the remaining patient population, and these patients were excluded. A whole-pelvis MRI atlas was generated based on the manually delineated MRI scans. In addition, a conjugate electron-density atlas was generated from the coregistered computed tomography (CT)-MRI scans. Pseudo-CT scans for each patient were automatically generated by global and nonrigid registration of the MRI atlas to the patient MRI scan, followed by application of the same transformations to the electron-density atlas. Comparisons were made between organ segmentations by using the Dice similarity coefficient (DSC) and point dose calculations for 26 patients on planning CT and pseudo-CT scans. Results: The agreement between pseudo-CT and planning CT was quantified by differences in the point dose at isocenter and distance to agreement in corresponding voxels. Dose differences were found to be less than 2%. Chi-squared values indicated that the planning CT and pseudo-CT dose distributions were equivalent. No significant differences (p > 0.9) were found between CT and pseudo-CT Hounsfield units for organs of interest. Mean {+-} standard deviation DSC scores for the atlas-based segmentation of the pelvic bones were 0.79 {+-} 0.12, 0.70 {+-} 0.14 for the prostate, 0.64 {+-} 0.16 for the bladder, and 0.63 {+-} 0.16 for the rectum. Conclusions: The electron-density atlas method provides the ability to automatically define organs and map realistic electron densities to MRI scans for radiotherapy dose planning and DRR generation. This method provides the necessary tools for MRI-alone treatment planning and adaptive MRI-based prostate radiation therapy.

  16. In Vivo Imaging with a Cell-Permeable Porphyrin-Based MRI Contrast

    E-Print Network [OSTI]

    Lee, Taekwan

    Magnetic resonance imaging (MRI) with molecular probes offers the potential to monitor physiological parameters with comparatively high spatial and temporal resolution in living subjects. For detection of intracellular ...

  17. In vivo imaging with a cell-permeable porphyrin-based MRI contrast agent

    E-Print Network [OSTI]

    Lee, Taekwan

    Magnetic resonance imaging (MRI) with molecular probes offers the potential to monitor physiological parameters with comparatively high spatial and temporal resolution in living subjects. For detection of intracellular ...

  18. An fMRI Study of Audiovisual Speech Perception Reveals Multisensory Interactions in Auditory Cortex

    E-Print Network [OSTI]

    Okada, Kayoko; Venezia, Jonathan H; Matchin, William; Saberi, Kourosh; Hickok, Gregory; Alain, Claude

    2013-01-01T23:59:59.000Z

    William Matchin, Kourosh Saberi, Gregory Hickok * DepartmentK, Venezia JH, Matchin W, Saberi K, Hickok G (2013) An fMRI

  19. A novel electron gun for inline MRI-linac configurations

    SciTech Connect (OSTI)

    Constantin, Drago? E., E-mail: dragos.constantin@varian.com; Fahrig, Rebecca [Department of Radiology, Stanford University, Stanford, California 94305 (United States)] [Department of Radiology, Stanford University, Stanford, California 94305 (United States); Holloway, Lois [Liverpool and Macarthur Cancer Therapy Centres, The University of Sydney, NSW 2006 (Australia)] [Liverpool and Macarthur Cancer Therapy Centres, The University of Sydney, NSW 2006 (Australia); Keall, Paul J. [Radiation Physics Laboratory, The University of Sydney, NSW 2006 (Australia)] [Radiation Physics Laboratory, The University of Sydney, NSW 2006 (Australia)

    2014-02-15T23:59:59.000Z

    Purpose: This work introduces a new electron gun geometry capable of robust functioning in the presence of a high strength external magnetic field for axisymmetric magnetic resonance imaging (MRI)-linac configurations. This allows an inline MRI-linac to operate without the need to isolate the linear accelerator (linac) using a magnetic shield. This MRI-linac integration approach not only leaves the magnet homogeneity unchanged but also provides the linac flexibility to move along the magnet axis of symmetry if the source to target distance needs to be adjusted. Methods: Simple electron gun geometry modifications of a Varian 600C electron gun are considered and solved in the presence of an external magnetic field in order to determine a set of design principles for the new geometry. Based on these results, a new gun geometry is proposed and optimized in the fringe field of a 0.5 T open bore MRI magnet (GE Signa SP). A computer model for the 6 MeV Varian 600C linac is used to determine the capture efficiency of the new electron gun-linac system in the presence of the fringe field of the same MRI scanner. The behavior of the new electron gun plus the linac system is also studied in the fringe fields of two other magnets, a 1.0 T prototype open bore magnet and a 1.5 T GE Conquest scanner. Results: Simple geometrical modifications of the original electron gun geometry do not provide feasible solutions. However, these tests show that a smaller transverse cathode diameter with a flat surface and a slightly larger anode diameter could alleviate the current loss due to beam interactions with the anode in the presence of magnetic fields. Based on these findings, an initial geometry resembling a parallel plate capacitor with a hole in the anode is proposed. The optimization procedure finds a cathode-anode distance of 5 mm, a focusing electrode angle of 5°, and an anode drift tube length of 17.1 mm. Also, the linac can be displaced with ±15 cm along the axis of the 0.5 T magnet without capture efficiency reduction below the experimental value in zero field. In this range of linac displacements, the electron beam generated by the new gun geometry is more effectively injected into the linac in the presence of an external magnetic field, resulting in approximately 20% increase of the target current compared to the original gun geometry behavior at zero field. The new gun geometry can generate and accelerate electron beams in external magnetic fields without current loss for fields higher than 0.11 T. The new electron-gun geometry is robust enough to function in the fringe fields of the other two magnets with a target current loss of no more than 16% with respect to the current obtained with no external magnetic fields. Conclusions: In this work, a specially designed electron gun was presented which can operate in the presence of axisymmetric strong magnetic fringe fields of MRI magnets. Computer simulations show that the electron gun can produce high quality beams which can be injected into a straight through linac such as Varian 600C and accelerated with more efficiency in the presence of the external magnetic fields. Also, the new configuration allows linac displacements along the magnet axis in a range equal to the diameter of the imaging spherical volume of the magnet under consideration. The new electron gun-linac system can function in the fringe field of a MRI magnet if the field strength at the cathode position is higher than 0.11 T. The capture efficiency of the linac depends on the magnetic field strength and the field gradient. The higher the gradient the better the capture efficiency. The capture efficiency does not degrade more than 16%.

  20. Combined fMRI and electrical microstimulation to determine functional connections in visual areas of the primate brain

    E-Print Network [OSTI]

    Ekstrom, Leeland Bruce

    2009-01-01T23:59:59.000Z

    The use of functional magnetic resonance imaging (fMRI) to study the non-human primate brain has been developed over the past decade. Primate fMRI has many attractive features: it allows validation of previous homology ...

  1. MRI of Heterogeneous Hydrogenation Reactions Using Parahydrogen Polarization

    SciTech Connect (OSTI)

    Burt, Scott R; Burt, Scott R.

    2008-06-25T23:59:59.000Z

    The power of magnetic resonance imaging (MRI) is its ability to image the internal structure of optically opaque samples and provide detailed maps of a variety of important parameters, such as density, diffusion, velocity and temperature. However, one of the fundamental limitations of this technique is its inherent low sensitivity. For example, the low signal to noise ratio (SNR) is particularly problematic for imaging gases in porous materials due to the low density of the gas and the large volume occluded by the porous material. This is unfortunate, as many industrially relevant chemical reactions take place at gas-surface interfaces in porous media, such as packed catalyst beds. Because of this severe SNR problem, many techniques have been developed to directly increase the signal strength. These techniques work by manipulating the nuclear spin populations to produce polarized} (i.e., non-equilibrium) states with resulting signal strengths that are orders of magnitude larger than those available at thermal equilibrium. This dissertation is concerned with an extension of a polarization technique based on the properties of parahydrogen. Specifically, I report on the novel use of heterogeneous catalysis to produce parahydrogen induced polarization and applications of this new technique to gas phase MRI and the characterization of micro-reactors. First, I provide an overview of nuclear magnetic resonance (NMR) and how parahydrogen is used to improve the SNR of the NMR signal. I then present experimental results demonstrating that it is possible to use heterogeneous catalysis to produce parahydrogen-induced polarization. These results are extended to imaging void spaces using a parahydrogen polarized gas. In the second half of this dissertation, I demonstrate the use of parahydrogen-polarized gas-phase MRI for characterizing catalytic microreactors. Specifically, I show how the improved SNR allows one to map parameters important for characterizing the heat and mass transport in a heterogeneous catalyst bed. This is followed by appendices containing detailed information regarding the design and use of my experimental setup.

  2. SQUID detected NMR and MRI at ultralow fields

    DOE Patents [OSTI]

    Clarke, John; McDermott, Robert; Pines, Alexander; Trabesinger, Andreas Heinz

    2005-04-26T23:59:59.000Z

    Nuclear magnetic resonance (NMR) signals are detected in microtesla fields. Prepolarization in millitesla fields is followed by detection with an untuned de superconducting quantum interference device (SQUID) magnetometer. Because the sensitivity of the SQUID is frequency independent, both signal-to-noise ratio (SNR) and spectral resolution are enhanced by detecting the NMR signal in extremely low magnetic fields, where the NMR lines become very narrow even for grossly inhomogeneous measurement fields. MRI in ultralow magnetic field is based on the NMR at ultralow fields. Gradient magnetic fields are applied, and images are constructed from the detected NMR signals.

  3. Squid detected NMR and MRI at ultralow fields

    DOE Patents [OSTI]

    Clarke, John; McDermott, Robert; Pines, Alexander; Trabesinger, Andreas Heinz

    2006-05-30T23:59:59.000Z

    Nuclear magnetic resonance (NMR) signals are detected in microtesla fields. Prepolarization in millitesla fields is followed by detection with an untuned dc superconducting quantum interference device (SQUID) magnetometer. Because the sensitivity of the SQUID is frequency independent, both signal-to-noise ratio (SNR) and spectral resolution are enhanced by detecting the NMR signal in extremely low magnetic fields, where the NMR lines become very narrow even for grossly inhomogeneous measurement fields. MRI in ultralow magnetic field is based on the NMR at ultralow fields. Gradient magnetic fields are applied, and images are constructed from the detected NMR signals.

  4. SQUID detected NMR and MRI at ultralow fields

    DOE Patents [OSTI]

    Clarke, John; McDermott, Robert; Pines, Alexander; Trabesinger, Andreas Heinz

    2006-10-03T23:59:59.000Z

    Nuclear magnetic resonance (NMR) signals are detected in microtesla fields. Prepolarization in millitesla fields is followed by detection with an untuned dc superconducting quantum interference device (SQUID) magnetometer. Because the sensitivity of the SQUID is frequency independent, both signal-to-noise ratio (SNR) and spectral resolution are enhanced by detecting the NMR signal in extremely low magnetic fields, where the NMR lines become very narrow even for grossly inhomogeneous measurement fields. MRI in ultralow magnetic field is based on the NMR at ultralow fields. Gradient magnetic fields are applied, and images are constructed from the detected NMR signals.

  5. Squid detected NMR and MRI at ultralow fields

    DOE Patents [OSTI]

    Clarke, John (Berkeley, CA); Pines, Alexander (Berkeley, CA); McDermott, Robert F. (Monona, WI); Trabesinger, Andreas H. (London, GB)

    2008-12-16T23:59:59.000Z

    Nuclear magnetic resonance (NMR) signals are detected in microtesla fields. Prepolarization in millitesla fields is followed by detection with an untuned dc superconducting quantum interference device (SQUID) magnetometer. Because the sensitivity of the SQUID is frequency independent, both signal-to-noise ratio (SNR) and spectral resolution are enhanced by detecting the NMR signal in extremely low magnetic fields, where the NMR lines become very narrow even for grossly inhomogeneous measurement fields. MRI in ultralow magnetic field is based on the NMR at ultralow fields. Gradient magnetic fields are applied, and images are constructed from the detected NMR signals.

  6. Squid detected NMR and MRI at ultralow fields

    DOE Patents [OSTI]

    Clarke, John (Berkeley, CA); McDermott, Robert (Louisville, CO); Pines, Alexander (Berkeley, CA); Trabesinger, Andreas Heinz (CH-8006 Zurich, CH)

    2007-05-15T23:59:59.000Z

    Nuclear magnetic resonance (NMR) signals are detected in microtesla fields. Prepolarization in millitesla fields is followed by detection with an untuned dc superconducting quantum interference device (SQUID) magnetometer. Because the sensitivity of the SQUID is frequency independent, both signal-to-noise ratio (SNR) and spectral resolution are enhanced by detecting the NMR signal in extremely low magnetic fields, where the NMR lines become very narrow even for grossly inhomogeneous measurement fields. MRI in ultralow magnetic field is based on the NMR at ultralow fields. Gradient magnetic fields are applied, and images are constructed from the detected NMR signals.

  7. Haptic System Design for MRI-Guided Needle Based Prostate Brachytherapy

    E-Print Network [OSTI]

    Camesano, Terri

    Gregory A. Cole Kevin Harrington Gregory S. Fischer ABSTRACT This paper presents the design of a hapticHaptic System Design for MRI-Guided Needle Based Prostate Brachytherapy Hao Su Weijian Shang system for prostate nee- dle brachytherapy under magnetic resonance imaging (MRI) guid- ance. This haptic

  8. fMRI Brain Image Retrieval Based on ICA Components bbai@cs.rutgers.edu

    E-Print Network [OSTI]

    fMRI Brain Image Retrieval Based on ICA Components Bing Bai bbai@cs.rutgers.edu Department This manuscript proposes a retrieval system for fMRI brain images. Our goal is to find a similarity- metric to enable us to support queries for "similar tasks" for retrieval on a large collection of brain ex

  9. 3D RECONSTRUCTION OF PLANT ROOTS FROM MRI IMAGES Hannes Schulz1

    E-Print Network [OSTI]

    Behnke, Sven

    distance measure by a multi-scale vesselness measure. As a result, paths running within good root candidates are preferred over paths in bare soil. We test this method using both virtually generated MRI) and Nuclear Magnetic Resonance Imaging (MRI) (Brown et al., 1990; Jahnke et al., 2009; Southon and Jones, 1992

  10. Multimodal dataset: Localising face-evoked responses using MEG, EEG, sMRI and

    E-Print Network [OSTI]

    Henson, Rik

    channel CTF Omega system; the sMRI data were acquired using a phased-array headcoil on a Siemens Sonata 1 transformation, random #12;2 phase permutation, inverse transformation and outline-masking of each face. Thus-weighted structural MRI of a young male was acquired on a 1.5T Siemens Sonata via an MDEFT sequence

  11. Suppressing Multi-Channel Ultra-Low-Field MRI Measurement Noise Using Data Consistency and Image

    E-Print Network [OSTI]

    Suppressing Multi-Channel Ultra-Low-Field MRI Measurement Noise Using Data Consistency and Image of Mathematics, National Taiwan University, Taipei, Taiwan, 4 Elekta Oy, Helsinki, Finland Abstract Ultra-low. (2013) Suppressing Multi-Channel Ultra-Low-Field MRI Measurement Noise Using Data Consistency and Image

  12. Automatic Scan Prescription for Brain MRI T. Ernst, L. Itti, L. Chang

    E-Print Network [OSTI]

    Itti, Laurent

    Automatic Scan Prescription for Brain MRI T. Ernst, L. Itti, L. Chang Harbor-UCLA Medical Center that allows the automatic prescription of brain MRI scans. This involves determination of the orientation of the current patient's brain, by matching his/her brain surface with a template brain surface. A desired

  13. MRI FINDINGS AND CLINICAL OUTCOME IN 45 DIVERS WITH SPINAL CORD DECOMPRESSION SICKNESS

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    1 MRI FINDINGS AND CLINICAL OUTCOME IN 45 DIVERS WITH SPINAL CORD DECOMPRESSION SICKNESS Emmanuel clinical outcome in divers with spinal cord DCS. The presence of medullary compressive factors was conducted to evaluate the relationship between spinal cord lesions on MRI and clinical findings in divers

  14. Abstract--Magnetic Resonance Imaging (MRI) guided nanorobotic systems that could perform diagnostic, curative

    E-Print Network [OSTI]

    Mavroidis, Constantinos

    groups have employed magnetized micro/ nanoparticles and have implemented magnetic propulsion techniquesAbstract-- Magnetic Resonance Imaging (MRI) guided nanorobotic systems that could perform on the use of a MRI scanner to induce the required external driving forces to guide magnetic nanocapsules

  15. Testing Oil Saturation Distribution in Migration Paths Using MRI1 Jianzhao Yan 1

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    - 1 - Testing Oil Saturation Distribution in Migration Paths Using MRI1 Jianzhao Yan 1 , Xiaorong media, and to measure oil and water saturation. Although this technique has great advantages compared14. Using15 MRI, the oil secondary migration paths are scanned to measure the saturation distribution during

  16. Real-time MRI-Guided Needle Placement Robot with Integrated Fiber Optic Force Sensing

    E-Print Network [OSTI]

    Camesano, Terri

    the robot mechanism, controller design, optical modeling and opto-mechanical design of the force sensor. MRI Control Box Needle Driver Module Cartesian Stage Module Piezoelectric Actuators Robot Fig. 1. (LeftReal-time MRI-Guided Needle Placement Robot with Integrated Fiber Optic Force Sensing Hao Su

  17. Automated Quality Assurance Routines for fMRI Data Applied to a Multicenter Study

    E-Print Network [OSTI]

    Gabrieli, John

    MRI) data and influence the sig- nificance and reliability of conclusions drawn from these data. Generally and Nichols, 2003], result reliability and variability [Casey et al., 1998; Le and Hu, 1997; Maitra et al of fMRI equipment has been considered less frequently [Simmons et al., 1999; Thulborn, 2002

  18. The neural correlates of statistical learning in a word segmentation task: An fMRI study

    E-Print Network [OSTI]

    Aslin, Richard N.

    history: Available online xxxx Keywords: fMRI Statistical learning Word segmentation Artificial language of this statistical learning mechanism in the do- main of language acquisition (see also Saffran, Aslin, & NewportThe neural correlates of statistical learning in a word segmentation task: An fMRI study Elisabeth

  19. A multichannel, real-time MRI RF power monitor for independent SAR determination

    SciTech Connect (OSTI)

    El-Sharkawy, AbdEl-Monem M.; Qian Di; Bottomley, Paul A.; Edelstein, William A. [Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins, University School of Medicine, Baltimore, Maryland 21287 (United States); Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins, University School of Medicine, Baltimore, Maryland 21287 (United States) and Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, Maryland 21287 (United States); Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins, University School of Medicine, Baltimore, Maryland 21287 (United States)

    2012-05-15T23:59:59.000Z

    Purpose: Accurate measurements of the RF power delivered during clinical MRI are essential for safety and regulatory compliance, avoiding inappropriate restrictions on clinical MRI sequences, and for testing the MRI safety of peripheral and interventional devices at known RF exposure levels. The goal is to make independent RF power measurements to test the accuracy of scanner-reported specific absorption rate (SAR) over the extraordinary range of operating conditions routinely encountered in MRI. Methods: A six channel, high dynamic range, real-time power profiling system was designed and built for monitoring power delivery during MRI up to 440 MHz. The system was calibrated and used in two 3 T scanners to measure power applied to human subjects during MRI scans. The results were compared with the scanner-reported SAR. Results: The new power measurement system has highly linear performance over a 90 dB dynamic range and a wide range of MRI duty cycles. It has about 0.1 dB insertion loss that does not interfere with scanner operation. The measurements of whole-body SAR in volunteers showed that scanner-reported SAR was significantly overestimated by up to about 2.2 fold. Conclusions: The new power monitor system can accurately and independently measure RF power deposition over the wide range of conditions routinely encountered during MRI. Scanner-reported SAR values are not appropriate for setting exposure limits during device or pulse sequence testing.

  20. MRI-free neuronavigation for transcranial magnetic stimulation in severe depression

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    MRI-free neuronavigation for transcranial magnetic stimulation in severe depression Beno^it Comb-35043 Rennes, France d Pontchaillou Univ. Hospital, Department of Neurosurgery, F-35033 Rennes, France e Syneika, F-35000 Rennes, France Abstract. This paper presents a MRI-free neuronavigation technique

  1. Asphalt roofing industry Fourier transform infrared spectroscopy modified bitumen

    SciTech Connect (OSTI)

    NONE

    1999-07-01T23:59:59.000Z

    A Request for Emissions Testing at Four Asphalt Roofing and Processing Facilities was submitted by the US EPA Emission Standards Division (ESD), Minerals and Inorganic Chemicals Group (MICG) to the Emission Measurement Center (EMC). The Emission Measurement Center directed Midwest Research Institute (MRI) to conduct emissions testing at asphalt roofing plants. This report presents results of MRI`s FTIR and Method 25A testing conducted at US Intec in Port Arthur, Texas. The field measurements were performed in September 1997 under several test conditions for both controlled and uncontrolled emissions.

  2. Atlas-based attenuation correction for small animal PET/MRI scanners Abhijit J. Chaudhari, ajchaudhari@ucdavis.edu,

    E-Print Network [OSTI]

    Leahy, Richard M.

    of MRI values to absolute CT intensities [3]. Rotating a PET transmission source around the animalAtlas-based attenuation correction for small animal PET/MRI scanners 1 Abhijit J. Chaudhari PET/MRI scanners producing anatomically co-registered simultaneously-acquired images of morphology

  3. RESEARCH REPORT 2012 ResearchResearchResearch

    E-Print Network [OSTI]

    Saldin, Dilano

    research on batteries and energy storage, and are part of a multimillion- dollar investment by Johnson Controls that aims to make Wisconsin a hub for energy-storage technology. #12;Chancellor's Welcome A great powerful UW-MILWAUKEE RESEARCH REPORT 2012 As Wisconsin's premier public urban institution, the University

  4. Applications of MRI in Fluidics: Single Echo Acquisition MRI Toward Microfluidics 

    E-Print Network [OSTI]

    Bosshard, John

    2006-08-16T23:59:59.000Z

    of mixing, much research has gone into constructing passive and active micromixers (60). Bend-induced vortices can enable a process called ?chaotic advection,? which accelerates mixing (25). One group has called the mixing of macromolecular analytes... them move randomly. Because they do not follow the flow exactly, time averaging is necessary, making PIV unsuited for unsteady flows (29). This system requires that at least part of the structure under study be optically transparent. Also...

  5. Evaluation of Artifacts and Distortions of Titanium Applicators on 3.0-Tesla MRI: Feasibility of Titanium Applicators in MRI-Guided Brachytherapy for Gynecological Cancer

    SciTech Connect (OSTI)

    Kim, Yusung, E-mail: yusung-kim@uiowa.edu [Department of Radiation Oncology, University of Iowa, Iowa City, IA (United States); Muruganandham, Manickam; Modrick, Joseph M.; Bayouth, John E. [Department of Radiation Oncology, University of Iowa, Iowa City, IA (United States)

    2011-07-01T23:59:59.000Z

    Purpose: The aim of this study was to characterize the levels of artifacts and distortions of titanium applicators on 3.0-Tesla magnetic resonance imaging (MRI). Methods and Materials: Fletcher-Suit-Delclos-style tandem and ovoids (T and O) and tandem and ring applicator (T and R) were examined. The quality assurance (QA) phantoms for each applicator were designed and filled with copper sulphate solution (1.5 g/l). The artifacts were quantified with the registration of corresponding computed tomography (CT) images. A favorable MR sequence was searched in terms of artifacts. Using the sequence, the artifacts were determined. The geometric distortions induced by the applicators were quantified through each registration of CT and MRI without applicators. The artifacts of T and O were also evaluated on in vivo MRI datasets of 5 patients. Results: T1-weighted MRI with 1-mm slice thickness was found as a favorable MR sequence. Applying the sequence, the artifacts at the tandem tip of T and O and T and R were determined as 1.5 {+-} 0.5 mm in a superior direction in phantom studies. In the ovoids of T and O, we found artifacts less than 1.5 {+-} 0.5 mm. The artifacts of a T and O tandem in vivo were found as less than 2.6 {+-} 1.3 mm on T1-weighted MRI, whereas less than 6.9 {+-} 3.4 mm on T2-weighted MRI. No more than 1.2 {+-} 0.6 mm (3.0 {+-} 1.5 mm) of distortions, due to a titanium applicator, were measured on T1-weighted MRI (T2-). Conclusion: In 3.0-Tesla MRI, we found the artifact widths at the tip of tandem were less than 1.5 {+-} 0.5 mm for both T and O and T and R when using T1-weighted MRI in phantom studies. However, exclusive 3.0-Tesla MRI-guided brachytherapy planning with a titanium applicator should be cautiously implemented.

  6. Proceedings of the Midwest Poultry Federation Convention, St. Paul, MN. March 16-18, 2004 Ammonia Emission from Iowa Layer Houses

    E-Print Network [OSTI]

    Kentucky, University of

    conversion as one of eight principles to reduce ammonia emission from layer hen houses. Research on reduction., Pittsburg, PA) for NH3 measurement and infrared sensor (0-5000 ± 20 ppm; Vaisala, Inc., Woburn, MA) for CO2 - Ammonia Emission from Iowa Layer Houses H. Xin1 , Y. Liang2 , R.S. Gates3 , E. F. Wheeler4 1 Professor

  7. NMR/MRI with hyperpolarized gas and high Tc SQUID

    DOE Patents [OSTI]

    Schlenga, Klaus (Eggenstein, DE); de Souza, Ricardo E. (Recife, BR); Wong-Foy, Annjoe (Berkeley, CA); Clarke, John (Berkeley, CA); Pines, Alexander (Berkeley, CA)

    2000-01-01T23:59:59.000Z

    A method and apparatus for the detection of nuclear magnetic resonance (NMR) signals and production of magnetic resonance imaging (MRI) from samples combines the use of hyperpolarized inert gases to enhance the NMR signals from target nuclei in a sample and a high critical temperature (Tc) superconducting quantum interference device (SQUID) to detect the NMR signals. The system operates in static magnetic fields of 3 mT or less (down to 0.1 mT), and at temperatures from liquid nitrogen (77K) to room temperature. Sample size is limited only by the size of the magnetic field coils and not by the detector. The detector is a high Tc SQUID magnetometer designed so that the SQUID detector can be very close to the sample, which can be at room temperature.

  8. Remote NMR/MRI detection of laser polarized gases

    DOE Patents [OSTI]

    Pines, Alexander; Saxena, Sunil; Moule, Adam; Spence, Megan; Seeley, Juliette A.; Pierce, Kimberly L.; Han, Song-I; Granwehr, Josef

    2006-06-13T23:59:59.000Z

    An apparatus and method for remote NMR/MRI spectroscopy having an encoding coil with a sample chamber, a supply of signal carriers, preferably hyperpolarized xenon and a detector allowing the spatial and temporal separation of signal preparation and signal detection steps. This separation allows the physical conditions and methods of the encoding and detection steps to be optimized independently. The encoding of the carrier molecules may take place in a high or a low magnetic field and conventional NMR pulse sequences can be split between encoding and detection steps. In one embodiment, the detector is a high magnetic field NMR apparatus. In another embodiment, the detector is a superconducting quantum interference device. A further embodiment uses optical detection of Rb--Xe spin exchange. Another embodiment uses an optical magnetometer using non-linear Faraday rotation. Concentration of the signal carriers in the detector can greatly improve the signal to noise ratio.

  9. Adjustable permanent magnet assembly for NMR and MRI

    DOE Patents [OSTI]

    Pines, Alexander; Paulsen, Jeffrey; Bouchard, Louis S; Blumich, Bernhard

    2013-10-29T23:59:59.000Z

    System and methods for designing and using single-sided magnet assemblies for magnetic resonance imaging (MRI) are disclosed. The single-sided magnet assemblies can include an array of permanent magnets disposed at selected positions. At least one of the permanent magnets can be configured to rotate about an axis of rotation in the range of at least +/-10 degrees and can include a magnetization having a vector component perpendicular to the axis of rotation. The single-sided magnet assemblies can further include a magnet frame that is configured to hold the permanent magnets in place while allowing the at least one of the permanent magnets to rotate about the axis of rotation.

  10. Numerical field simulation for parallel transmission in MRI at 7 tesla

    E-Print Network [OSTI]

    Bernier, Jessica A. (Jessica Ashley)

    2011-01-01T23:59:59.000Z

    Parallel transmission (pTx) is a promising improvement to coil design that has been demonstrated to mitigate B1* inhomogeneity, manifest as center brightening, for high-field magnetic resonance imaging (MRI). Parallel ...

  11. Neurovascular coupling to D2/D3 dopamine receptor occupancy using simultaneous PET/functional MRI

    E-Print Network [OSTI]

    Sander, Christin Yen-Ming

    This study employed simultaneous neuroimaging with positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) to demonstrate the relationship between changes in receptor occupancy measured by PET ...

  12. Probing the brain’s white matter with diffusion MRI and a tissue dependent diffusion model 

    E-Print Network [OSTI]

    Piatkowski, Jakub Przemyslaw

    2014-06-27T23:59:59.000Z

    While diffusion MRI promises an insight into white matter microstructure in vivo, the axonal pathways that connect different brain regions together can only partially be segmented using current methods. Here we present ...

  13. Solid-Cryogen Cooling Technique for Superconducting Magnets of NMR and MRI

    E-Print Network [OSTI]

    Iwasa, Yukikazu

    This paper describes a solid-cryogen cooling technique currently being developed at the M.I.T. Francis Bitter Magnet Laboratory for application to superconducting magnets of NMR and MRI. The technique is particularly ...

  14. Brown Adipose Tissue Quantification in Human Neonates Using Water-Fat Separated MRI

    E-Print Network [OSTI]

    2013-01-01T23:59:59.000Z

    1) derived directly from the Siemens operating system, aMRI was performed on a Siemens 3 T Tim Trio system (VB17the re-shim and default Siemens pre-scan preparations. The

  15. Solutions to various problems in reversible cooling fMRI studies

    E-Print Network [OSTI]

    Khachaturian, Mark Haig, 1979-

    2003-01-01T23:59:59.000Z

    Functional magnetic resonance imaging (fMRI) has been very useful in helping neuroscientists map the brain. One tool to investigate the interactions between brain regions is to disable a small region in the brain, and look ...

  16. Spiral-In/Out BOLD fMRI for Increased SNR and Reduced Susceptibility Artifacts

    E-Print Network [OSTI]

    Glover, Gary H.

    Spiral-In/Out BOLD fMRI for Increased SNR and Reduced Susceptibility Artifacts Gary H. Glover, and by Glover (9), who used extended coverage of kz-space with windowed reconstruc- tion to provide efficiency

  17. Automated perfusion-weighted MRI metrics via localized arterial input functions

    E-Print Network [OSTI]

    Lorenz, Cory, 1981-

    2004-01-01T23:59:59.000Z

    This thesis describes and validates a new method for calculating perfusion-weighted MRI (PWI) metrics, a non-invasive technique for calculating cerebral blood flow by tracking a bolus of contrast agent. Past methods to do ...

  18. Segmentation of Spin-Echo MRI brain images: a comparison study of Crisp and Fuzzy algorithms

    E-Print Network [OSTI]

    Chung, Maranatha

    1993-01-01T23:59:59.000Z

    This thesis presents a scheme for segmenting Spin-Echo MRI brain images based on Fuzzy C-Mean (FCM) clustering techniques. This scheme consists of feature extraction, feature conditioning or evaluation, and thresholded FCM clustering. Feature...

  19. agent-enhanced mri measuring: Topics by E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Thorstensen,1 M. Hofer,2 G. Sapiro,3 and H for population and longitudinal studies in brain imag- ing. Therefore, measuring cortical thickness from MRI data, and ignore the...

  20. MRI Magnetic Signature Imaging, Tracking and Navigation for Targeted Micro/Nano-capsule Therapeutics

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    - back for the microdevice and a propulsion sequence to enable interleaved magnetic propulsionMRI Magnetic Signature Imaging, Tracking and Navigation for Targeted Micro J. Nelson, Antoine Ferreira and Sergej Fatikow Abstract-- The propulsion of nano

  1. Undersampling to accelerate time-resolved MRI velocity measurement of carotid blood flow 

    E-Print Network [OSTI]

    Tao, Yuehui

    2009-01-01T23:59:59.000Z

    Time-resolved velocity information of carotid blood flow can be used to estimate haemodynamic conditions associated with carotid artery disease leading to stroke. MRI provides high-resolution measurement of such information ...

  2. Predictive models of tissue outcome in acute human cerebral ischemia using diffusion and perfusion weighted MRI

    E-Print Network [OSTI]

    Wu, Ona

    2002-01-01T23:59:59.000Z

    Diffusion (DWI) and perfusion weighted (PWI) magnetic resonance imaging (MRI) provide significant insight into acute stroke and can potentially be useful for clinical decision-making. In particular, current therapeutic ...

  3. A dual model HU conversion from MRI intensity values within and outside of bone segment for MRI-based radiotherapy treatment planning of prostate cancer

    SciTech Connect (OSTI)

    Korhonen, Juha, E-mail: juha.p.korhonen@hus.fi [Clinical Research Institute Helsinki University Central Hospital Ltd., POB-700, 00029 HUS (Finland) [Clinical Research Institute Helsinki University Central Hospital Ltd., POB-700, 00029 HUS (Finland); Department of Oncology, Helsinki University Central Hospital, POB-180, 00029 HUS (Finland); Kapanen, Mika [Clinical Research Institute Helsinki University Central Hospital Ltd., POB-700, 00029 HUS (Finland) [Clinical Research Institute Helsinki University Central Hospital Ltd., POB-700, 00029 HUS (Finland); Department of Oncology, Helsinki University Central Hospital, POB-180, 00029 HUS (Finland); Department of Medical Physics, Tampere University Hospital, POB-2000, 33521 Tampere (Finland); Keyriläinen, Jani; Seppälä, Tiina; Tenhunen, Mikko [Department of Oncology, Helsinki University Central Hospital, POB-180, 00029 HUS (Finland)] [Department of Oncology, Helsinki University Central Hospital, POB-180, 00029 HUS (Finland)

    2014-01-15T23:59:59.000Z

    Purpose: The lack of electron density information in magnetic resonance images (MRI) poses a major challenge for MRI-based radiotherapy treatment planning (RTP). In this study the authors convert MRI intensity values into Hounsfield units (HUs) in the male pelvis and thus enable accurate MRI-based RTP for prostate cancer patients with varying tissue anatomy and body fat contents. Methods: T{sub 1}/T{sub 2}*-weighted MRI intensity values and standard computed tomography (CT) image HUs in the male pelvis were analyzed using image data of 10 prostate cancer patients. The collected data were utilized to generate a dual model HU conversion technique from MRI intensity values of the single image set separately within and outside of contoured pelvic bones. Within the bone segment local MRI intensity values were converted to HUs by applying a second-order polynomial model. This model was tuned for each patient by two patient-specific adjustments: MR signal normalization to correct shifts in absolute intensity level and application of a cutoff value to accurately represent low density bony tissue HUs. For soft tissues, such as fat and muscle, located outside of the bone contours, a threshold-based segmentation method without requirements for any patient-specific adjustments was introduced to convert MRI intensity values into HUs. The dual model HU conversion technique was implemented by constructing pseudo-CT images for 10 other prostate cancer patients. The feasibility of these images for RTP was evaluated by comparing HUs in the generated pseudo-CT images with those in standard CT images, and by determining deviations in MRI-based dose distributions compared to those in CT images with 7-field intensity modulated radiation therapy (IMRT) with the anisotropic analytical algorithm and 360° volumetric-modulated arc therapy (VMAT) with the Voxel Monte Carlo algorithm. Results: The average HU differences between the constructed pseudo-CT images and standard CT images of each test patient ranged from ?2 to 5 HUs and from 22 to 78 HUs in soft and bony tissues, respectively. The average local absolute value differences were 11 HUs in soft tissues and 99 HUs in bones. The planning target volume doses (volumes 95%, 50%, 5%) in the pseudo-CT images were within 0.8% compared to those in CT images in all of the 20 treatment plans. The average deviation was 0.3%. With all the test patients over 94% (IMRT) and 92% (VMAT) of dose points within body (lower than 10% of maximum dose suppressed) passed the 1 mm and 1% 2D gamma index criterion. The statistical tests (t- and F-tests) showed significantly improved (p ? 0.05) HU and dose calculation accuracies with the soft tissue conversion method instead of homogeneous representation of these tissues in MRI-based RTP images. Conclusions: This study indicates that it is possible to construct high quality pseudo-CT images by converting the intensity values of a single MRI series into HUs in the male pelvis, and to use these images for accurate MRI-based prostate RTP dose calculations.

  4. Zinc ferrite nanoparticles as MRI contrast agentsw Carlos Ba rcena,a

    E-Print Network [OSTI]

    Gao, Jinming

    Zinc ferrite nanoparticles as MRI contrast agentsw Carlos Ba´ rcena,a Amandeep K. Sra,a Girija S, a series of spinel-structured ferrites, MFe2O4 (M = Mn2+ , Fe2+ , Co2+ , Ni2+ ), were reported as novel MRI.e., Mn2+ occupies both A and B sites), whereas the other metal ferrites have an inverse spinel structure

  5. Semi-automatic delineation using weighted CT-MRI registered images for radiotherapy of nasopharyngeal cancer

    SciTech Connect (OSTI)

    Fitton, I. [European Georges Pompidou Hospital, Department of Radiology, 20 rue Leblanc, 75015, Paris (France); Cornelissen, S. A. P. [Image Sciences Institute, UMC, Department of Radiology, P.O. Box 85500, 3508 GA Utrecht (Netherlands); Duppen, J. C.; Rasch, C. R. N.; Herk, M. van [The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Department of Radiotherapy, Plesmanlaan 121, 1066 CX Amsterdam (Netherlands); Steenbakkers, R. J. H. M. [University Medical Center Groningen, Department of Radiation Oncology, Hanzeplein 1, 9713 GZ Groningen (Netherlands); Peeters, S. T. H. [UZ Gasthuisberg, Herestraat 49, 3000 Leuven, Belgique (Belgium); Hoebers, F. J. P. [Maastricht University Medical Center, Department of Radiation Oncology (MAASTRO clinic), GROW School for Oncology and Development Biology Maastricht, 6229 ET Maastricht (Netherlands); Kaanders, J. H. A. M. [UMC St-Radboud, Department of Radiotherapy, Geert Grooteplein 32, 6525 GA Nijmegen (Netherlands); Nowak, P. J. C. M. [ERASMUS University Medical Center, Department of Radiation Oncology,Groene Hilledijk 301, 3075 EA Rotterdam (Netherlands)

    2011-08-15T23:59:59.000Z

    Purpose: To develop a delineation tool that refines physician-drawn contours of the gross tumor volume (GTV) in nasopharynx cancer, using combined pixel value information from x-ray computed tomography (CT) and magnetic resonance imaging (MRI) during delineation. Methods: Operator-guided delineation assisted by a so-called ''snake'' algorithm was applied on weighted CT-MRI registered images. The physician delineates a rough tumor contour that is continuously adjusted by the snake algorithm using the underlying image characteristics. The algorithm was evaluated on five nasopharyngeal cancer patients. Different linear weightings CT and MRI were tested as input for the snake algorithm and compared according to contrast and tumor to noise ratio (TNR). The semi-automatic delineation was compared with manual contouring by seven experienced radiation oncologists. Results: A good compromise for TNR and contrast was obtained by weighing CT twice as strong as MRI. The new algorithm did not notably reduce interobserver variability, it did however, reduce the average delineation time by 6 min per case. Conclusions: The authors developed a user-driven tool for delineation and correction based a snake algorithm and registered weighted CT image and MRI. The algorithm adds morphological information from CT during the delineation on MRI and accelerates the delineation task.

  6. A national laboratory of the U.S. Department of Energy Office of Energy Efficiency & Renewable Energy

    E-Print Network [OSTI]

    of Energy Office of Energy Efficiency and Renewable Energy by Midwest Research Institute · Battelle Contract is a national laboratory of the U.S. Department of Energy (DOE) managed by Midwest Research Institute for the U Department of Energy (DOE). Neither Midwest Research Institute, nor the DOE, nor the California Energy

  7. Amplification of Xenon NMR and MRI by remote detection

    SciTech Connect (OSTI)

    Moule, Adam J.; Spence, Megan M.; Han, Song-I.; Seeley, JulietteA.; Pierce, Kimberly L.; Saxena, Sunil; Pines, Alexander

    2003-03-31T23:59:59.000Z

    A novel technique is proposed in which a nuclear magneticresonance (NMR) spectrum or magnetic resonance image (MRI) is encoded andstored as spin polarization and is then moved to a different physicallocation to be detected. Remote detection allows the separateoptimization of the encoding and detection steps, permitting theindependent choice of experimental conditions, and excitation anddetection methodologies. In the first experimental demonstration of thistechnique, we show that NMR signal can be amplified by taking diluted129Xe from a porous sample placed inside a large encoding coil, andconcentrating it into a smaller detection coil. In general, the study ofNMR active molecules at low concentration that have low physical fillingfactor is facilitated by remote detection. In the second experiment, MRIinformation encoded in a very low field magnet (4-7mT) is transferred toa high field magnet (4.2 T) in order to be detected under optimizedconditions. Furthermore, remote detection allows the utilization ofultra-sensitive optical or superconducting detection techniques, whichbroadens the horizon of NMR experimentation.

  8. MAPPING HUMAN BRAIN FUNCTION WITH MRI AT 7 TESLA Xiaoping HU, Essa YACOUB, Josef PFEUFFER, Amir SCHUMEL,

    E-Print Network [OSTI]

    in a group of subjects at both 7 Tesla and 4 Telsa[1]. Functional MRI data were collected with multiple TEs

  9. SU-E-J-153: MRI Based, Daily Adaptive Radiotherapy for Rectal Cancer: Contour Adaptation

    SciTech Connect (OSTI)

    Kleijnen, J; Burbach, M; Verbraeken, T; Weggers, R; Zoetelief, A; Reerink, O; Lagendijk, J; Raaymakers, B; Asselen, B [University Medical Center Utrecht, Utrecht (Netherlands)

    2014-06-01T23:59:59.000Z

    Purpose: A major hurdle in adaptive radiotherapy is the adaptation of the planning MRI's delineations to the daily anatomy. We therefore investigate the accuracy and time needed for online clinical target volume (CTV) adaptation by radiation therapists (RTT), to be used in MRI-guided adaptive treatments on a MRI-Linac (MRL). Methods: Sixteen patients, diagnosed with early stage rectal cancer, underwent a T2-weighted MRI prior to each fraction of short-course radiotherapy, resulting in 4–5 scans per patient. On these scans, the CTV was delineated according to guidelines by an experienced radiation oncologist (RO) and considered to be the gold standard. For each patient, the first MRI was considered as the planning MRI and matched on bony anatomy to the 3–4 daily MRIs. The planning MRI's CTV delineation was rigidly propagated to the daily MRI scans as a proposal for adaptation. Three RTTs in training started the adaptation of the CTV conform guidelines, after a two hour training lecture and a two patient (n=7) training set. To assess the inter-therapist variation, all three RTTs altered delineations of 3 patients (n=12). One RTT altered the CTV delineations (n=53) of the remaining 11 patients. Time needed for adaptation of the CTV to guidelines was registered.As a measure of agreement, the conformity index (CI) was determined between the RTTs' delineations as a group. Dice similarity coefficients were determined between delineations of the RTT and the RO. Results: We found good agreement between RTTs' and RO's delineations (average Dice=0.91, SD=0.03). Furthermore, the inter-observer agreement between the RTTs was high (average CI=0.94, SD=0.02). Adaptation time reduced from 10:33 min (SD= 3:46) to 2:56 min (SD=1:06) between the first and last ten delineations, respectively. Conclusion: Daily CTV adaptation by RTTs, seems a feasible and safe way to introduce daily, online MRI-based plan adaptation for a MRL.

  10. MRI Investigations of Particle Motion within a Three-Dimensional Vibro-Fluidized Granular Bed

    E-Print Network [OSTI]

    Mick D. Mantle; Andrew J. Sederman; Lynn F. Gladden; Jonathan M. Huntley; Tom W. Martin Ricky D. Wildman; Mark D. Shattuck

    2007-02-08T23:59:59.000Z

    The unique ability of magnetic resonance imaging (MRI) to provide spatial and temporal information from optically opaque systems, in three dimensions, make it an ideal tool to study the internal motion of rapid granular flows. This paper will focus on the use of ultra-fast velocity compensated MRI measurements to study particle velocity and density distributions in a granular gas, produced by vibrating vertically a bed of mustard seeds at 40 Hz. Specifically, a velocity compensated, double spin-echo, triggered, one-dimensional MRI profiling pulse sequence was developed. This gives an MRI temporal resolution of approximately 2 ms and also minimises MRI velocity artefacts. 12 phase measurements per vibration cycle were used. The data can be used to extract values of the mustard seed average velocity and velocity propagators (probability distributions functions) as a function of the phase of the vibration cycle and vertical height within the cell. The data show strong transient effects during the impact phase of the vibration. A detailed discussion of the temporal passage of the individual phase resolved, height resolved velocity distributions, along with seed velocity propagators at a fix height from the vibrating base is presented.

  11. Research Report Age effects on load-dependent brain activations in working

    E-Print Network [OSTI]

    Research Report Age effects on load-dependent brain activations in working memory for novel being scanned with bold fMRI. The stimuli in the DIR task consisted of computer-generated closed-curve to the young participants. Spatial patterns of brain activation that corresponded to load-dependent (stimulus

  12. Seeking the neural basis of grammar : English noun and verb morphological processing investigated with rapid event-related fMRI and intracortical electrophysiology

    E-Print Network [OSTI]

    Sahin, Nedim T. (Nedim Turan), 1975-

    2003-01-01T23:59:59.000Z

    (cont.) the functionality of the fMRI data analysis and visualization tools used at Massachusetts General Hospital. I analyze and interpret an 18-subject fMRI experiment I ran using the new task design and software tools. ...

  13. National Renewable Energy Laboratory Innovation for Our Energy Future

    E-Print Network [OSTI]

    of the U.S. Department of Energy Office of Energy Efficiency & Renewable Energy NREL is operated by Midwest Energy by Midwest Research Institute · Battelle Contract No. DE-AC36-99-GO10337 #12;NOTICE This report.S. Department of Energy (DOE) managed by Midwest Research Institute for the U.S. Department of Energy under

  14. Plant root system analysis from MRI images Hannes Schulz1, Johannes A. Postma2, Dagmar van Dusschoten2,

    E-Print Network [OSTI]

    Behnke, Sven

    voxel to the base of the plant root, weighing the Euclidean distance measure by a multi-scale vesselness test this method using both virtually generated MRI images of Maize and real MRI images of Barley roots (Ferreira et al., 2010; Nakanishi et al., 2003; Pierret et al., 2003) and Nuclear Magnetic Resonance Imaging

  15. Stable Modality-Specific Activity Flows As Reflected by the Neuroenergetic Approach to the fMRI Weighted Maps

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    in the metabolic rate of glucose (PET with FDG) [5]. fMRI measures the consumption of energy by the brain through reflected by the increase of blood flow, blood oxygenation (PET with H2O15 and BOLD fMRI), the increase oxygen consumption, which is needed for the synthesis of the energy-carrying ATP molecules. This energy

  16. 1248 IEEE TRANSACTIONS ON NUCLEAR SCIENCE, VOL. 53, NO. 3, JUNE 2006 Aligning Emission Tomography and MRI Images

    E-Print Network [OSTI]

    . These methods depend on accurate registration of PET/SPECT and MRI/CT images. Herein, we consider registration using PET/SPECT projec- tion data only. Index Terms--CT, image reconstruction, MRI, PET, registra- tion, Fellow, IEEE Abstract--An important approach to reconstructing PET and SPECT (PET/SPECT) radiotracer

  17. Integrated microchip incorporating atomic magnetometer and microfluidic channel for NMR and MRI

    DOE Patents [OSTI]

    Ledbetter, Micah P. (Oakland, CA); Savukov, Igor M. (Los Alamos, NM); Budker, Dmitry (El Cerrito, CA); Shah, Vishal K. (Plainsboro, NJ); Knappe, Svenja (Boulder, CO); Kitching, John (Boulder, CO); Michalak, David J. (Berkeley, CA); Xu, Shoujun (Houston, TX); Pines, Alexander (Berkeley, CA)

    2011-08-09T23:59:59.000Z

    An integral microfluidic device includes an alkali vapor cell and microfluidic channel, which can be used to detect magnetism for nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI). Small magnetic fields in the vicinity of the vapor cell can be measured by optically polarizing and probing the spin precession in the small magnetic field. This can then be used to detect the magnetic field of in encoded analyte in the adjacent microfluidic channel. The magnetism in the microfluidic channel can be modulated by applying an appropriate series of radio or audio frequency pulses upstream from the microfluidic chip (the remote detection modality) to yield a sensitive means of detecting NMR and MRI.

  18. 2nd Annual Midwest Actuarial Student Conference

    E-Print Network [OSTI]

    2014-10-03T23:59:59.000Z

    Oct 3, 2014 ... The Conference has been set up to permit many attendees to arrive in the morning and leave in the late afternoon. However, if you arrive the ...

  19. Coal slurry pipeline based midwest fuel hub

    SciTech Connect (OSTI)

    Huettenhain, H. [Bechtel Technology & Consulting San Francisco, CA (United States)

    1998-12-31T23:59:59.000Z

    Low sulfur Powder River Basin (PRB) coal is a sought after fuel to comply with the year 2000 emission regulation for utility boilers. PRB coal is presently not competitive East of the Mississippi mainly because of railroad switching requirements and boiler designs not compatible with the PRB fuel characteristics. The use of the Lakes for transportation is an exception. The Lakes shipping lanes however, are only open part of the year. It is proposed to construct a coal slurry pipeline from the center of Wyoming coalfields to a hub near Detroit with access to low cost waste energy from power generation stations. The coal slurry pipeline will transport up to 25 million tons per year of fine PRB coal which has been removed from the conventionally transported coal, namely coal transported by rail. The rail delivered coal will have less dust. The system fits the DOE Vision 21 concept to mine and utilize coal in highly efficient systems and with the least environmental impact. The PRB coal is of subbituminous rank and not directly compatible with the boilers in Michigan/Indiana/Ohio area, which are designed to burn bituminous coal. Upgrading of the PRB coal using the hydrothermal slurry upgrading process can transform the PRB coal into a higher Btu content fuel by removing a large portion of the inherent moisture. Such upgraded PRB coal has proven an excellent reactive fuel when burned conventionally as PC fuel, or even when burned in slurry form as Coal Water Fuel (CWF). The cost of the process can be recovered when the process is combined with a coal slurry pipeline transport system. The result is an upgraded competitive fuel or fuels, which can be used for co-firing or re-burning applications to reduce SO{sub 2} and NOx emissions of utility boilers. The fuels can be powdered for direct fuel injection into boilers or blast furnaces as well as CWF. Depending on the stability of the upgraded PRB coal, the pipeline product could also be dewatered and prepared for export. This paper describes the concept and preliminary cost information. It also reports on reactions of the industries, which could be involved in the complex system, namely, coal mining companies, railroads, pipeline operators, fuel suppliers, and utilities.

  20. Midwest Partial Differential Equations Conference: Abstracts

    E-Print Network [OSTI]

    Much of the known theory for NLS blowup relies upon energy conservation and is thus restricted to H1 solutions, even though the NLS evolution problem is ...

  1. Schedule | 72nd Midwest PDE Seminar

    E-Print Network [OSTI]

    Charles Smart, MIT. Quantitative stochastic homogenization of non-divergence form elliptic equations. 4:00—4:30. Coffee break. MATH Library Lounge.

  2. Midwest Region Combined Heat and Power Projects

    Broader source: Energy.gov [DOE]

    DOE's CHP Technical Assistance Partnerships (CHP TAPs) have compiled a select number of combined heat and power (CHP) project profiles, which are available as Adobe Acrobat PDFs. 

  3. Mid-West Electric Consumers Association

    Broader source: Energy.gov (indexed) [DOE]

    new authority separately from its responsibilities under its Open Access Transmission Tariff (OATT); will give higher priority to these new projects than its current OATT...

  4. Public Evaluation of HSR, and Midwest Perspectives

    E-Print Network [OSTI]

    Bustamante, Fabián E.

    --why not? ­ Spillovers · Economic Development (eminent domain etc. who else can do the big projects?) ­ "Network" gains (connectivity/density) ­ Nodal development ­ "Job creation" macro-economic "costless resources" · Environment (market prices don't reflect these costs and benefits) · But let the public buyer

  5. Midwest Area Chinese American Resources Guide

    E-Print Network [OSTI]

    Chinese American Librarians Association - Midwest Chapter; Wu, Pei-ling; McElroy, Anna; Chang, Ling-li; Sanders, R. Bruce; Lin, Shao-Chen

    1995-01-01T23:59:59.000Z

    of ethnic Chinese from South East Asia. Generally speaking, since 1910, there has been a steady increase of the Chinese population in Chicago, regardless of the decrease of Chinese population coming into this country. Chinese Settlements in St. Louis... and began to settle in St. Louis and the other Midwestern cities in 1869. A majority of these Chinese became cigar makers. In 1874, White unionized cigar makers in San Francisco called on the proprietors of stores to boycott Chinese-made cigars...

  6. 2008 Midwest Levee Failure: Erosion Studies 

    E-Print Network [OSTI]

    Bernhardt, Michelle Lee

    2011-02-22T23:59:59.000Z

    The United States contains an estimated 100,000 miles (160000 km) of levees in which erosion related issues are the top priorities. Proper documentation of overtopping induced erosion is a complicated issue involving the ...

  7. Clean Energy Manufacturing Initiative Midwest Regional Summit:

    Office of Environmental Management (EM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742 33 1112011AT&T, Inc.'sEnergyTexas1. FeedstockCLEAN AIR ACT § 309* §7609.Lightweighting

  8. Clean Energy Manufacturing Initiative Midwest Regional Summit:

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742Energy China U.S. Department ofJuneWasteDepartmentUtilitiesStephen GraffofNeighborhood

  9. Midwest Biodiesel Producers LLC | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov YouKizildere I Geothermal Pwer Plant JumpMarysville, Ohio:Menomonee| OpenMickeyDelaware: EnergyMidnight PointMidway,

  10. Midwest Grain Processors MGP | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov YouKizildere I Geothermal Pwer Plant JumpMarysville, Ohio:Menomonee| OpenMickeyDelaware: EnergyMidnightProducers Inc

  11. Midwest Renewable Energy Corporation | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov YouKizildere I Geothermal Pwer Plant JumpMarysville, Ohio:Menomonee| OpenMickeyDelaware: EnergyMidnightProducers

  12. Midwest Renewable Energy LLC | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov YouKizildere I Geothermal Pwer Plant JumpMarysville, Ohio:Menomonee| OpenMickeyDelaware: EnergyMidnightProducersLLC Place:

  13. Midwest Wind Energy LLC | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov YouKizildere I Geothermal Pwer Plant JumpMarysville, Ohio:Menomonee| OpenMickeyDelaware: EnergyMidnightProducersLLCMidwest

  14. Midwest Wind Finance LLC | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov YouKizildere I Geothermal Pwer Plant JumpMarysville, Ohio:Menomonee| OpenMickeyDelaware:

  15. Midwest Energy Cooperative | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directedAnnual SiteofEvaluatingGroup |JilinLu anMicrogreen Polymers Inc Jump to:Jump

  16. ITC Midwest LLC | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directedAnnual SiteofEvaluatingGroup | OpenHunan Runhua New EnergyIT Power Limited Jump to: navigation,ITCITC

  17. ORIGINAL ARTICLES An fMRI Study of Anterior Cingulate Function in

    E-Print Network [OSTI]

    Whalen, Paul J.

    integrity of anterior cingulate cortex in PTSD. Methods: Eight Vietnam combat veterans with PTSD (PTSD Group) and eight Vietnam combat veterans without PTSD (non-PTSD Group) underwent functional magnetic resonance General Negative compar- ison, the non-PTSD group exhibited significant fMRI blood oxygenation level

  18. Quantitative Clinical Evaluation of a Simultaneous PETI MRI Breast Imaging System

    SciTech Connect (OSTI)

    Schlyer D. J.; Schlyer, D.J.

    2013-04-03T23:59:59.000Z

    A prototype simultaneous PET-MRI breast scanner has been developed for conducting clinical studies with the goal of obtaining high resolution anatomical and functional information in the same scan which can lead to faster and better diagnosis, reduction of unwanted biopsies, and better patient care.

  19. Off-resonance and detuned surface coils for B? inhomogeneity in 7-Tesla MRI

    E-Print Network [OSTI]

    Zakszewski, Elizabeth K

    2006-01-01T23:59:59.000Z

    A problem with high-field MRI is the lack of B1 homogeneity, particularly signal cancellation in the outer parts of the head. Here we attempt to correct this by adding surface coils. To adjust the mutual coupling, we vary ...

  20. A Framework for Integrating real-time MRI with Robot Control: Application to Simulated

    E-Print Network [OSTI]

    Azevedo, Ricardo

    1 A Framework for Integrating real-time MRI with Robot Control: Application to Simulated applications in urology [2], cardiac ablation with fluoroscopy guided Sensei robotic catheter system (Hansen interventional paradigms including image-guided robot assistance. Most often the use of an intraoperative imaging

  1. N-Alkyl-polyethylenimine 2 kDastabilized superparamagnetic iron oxide nanoparticles for MRI cell tracking

    E-Print Network [OSTI]

    Levin, Judith G.

    nanoparticles need to be coated with organic polymers or other materials for efficient cell labeling. This surface coating increases the stability of SPIO nanoparticles and allows further chemical modificationsN-Alkyl-polyethylenimine 2 kDa­stabilized superparamagnetic iron oxide nanoparticles for MRI cell

  2. Fractal-driven distortion of resting state functional networks in fMRI: a simulation study

    E-Print Network [OSTI]

    Fractal-driven distortion of resting state functional networks in fMRI: a simulation study Wonsang, Magdeburg, Germany E-mail: you@lin-magdeburg.de Fractals are self-similar and scale-invariant patterns found ubiquitously in nature. A lot of evidences implying fractal properties such as 1/f power spectrums have been

  3. SLIDING MODE CONTROL OF PIEZOELECTRIC VALVE REGULATED PNEUMATIC ACTUATOR FOR MRI-COMPATIBLE ROBOTIC INTERVENTION

    E-Print Network [OSTI]

    Camesano, Terri

    @wpi.edu ABSTRACT This paper presents the design of a magnetic resonance imaging (MRI) compatible pneumatic actuator@wpi.edu Gregory S. Fischer Mechanical Engineering Worcester Polytechnic Institute Worcester, MA 01609 gfischer provides high-fidelity soft tissue contrast and high spatial resolution. However, the high- field magnetic

  4. MRI Magnet Design: Search Space Analysis, EDAs and a Real-World Problem with Significant Dependencies

    E-Print Network [OSTI]

    Gallagher, Marcus

    MRI Magnet Design: Search Space Analysis, EDAs and a Real-World Problem with Significant Dependencies Bo Yuan School of Information Technology and Electrical Engineering The University of Queensland Technology and Electrical Engineering The University of Queensland QLD 4072, Australia +61-7-33656197 marcusg

  5. Tools of the Trade Region of interest analysis for fMRI

    E-Print Network [OSTI]

    Poldrack, Russ

    of California Los Angeles, Los Angeles, CA, USA A common approach to the analysis of fMRI data involves on the resulting data if the selection of the ROI was based on the same contrast; because the region was chosen assumptions. The first reason to perform an ROI analysis is simply to explore one's data. In complex designs

  6. High Gain Observer for Backstepping Control of a MRI-guided Therapeutic Microrobot in Blood Vessels

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    -planned trajectory inherited from the model, with robustness concerns. This paper reports modeling and controlHigh Gain Observer for Backstepping Control of a MRI-guided Therapeutic Microrobot in Blood Vessels Laurent Arcese, Ali Cherry, Matthieu Fruchard, Antoine Ferreira Abstract-- This paper reports modeling

  7. 7 Tesla fMRI Reveals Systematic Functional Organization for Binocular Disparity in Dorsal Visual Cortex

    E-Print Network [OSTI]

    Goncalves, Nuno R.; Ban, Hiroshi; Sánchez-Panchuelo, Rosa M.; Francis, Susan T.; Schluppeck, Denis; Welchman, Andrew E.

    2015-02-18T23:59:59.000Z

    animal models, comparatively little is known about the local architecture of stereoscopic processing in the human brain. Here, we take advantage of the high spatial specificity and image contrast offered by 7 tesla fMRI to test for systematic organization...

  8. Bone Motion Analysis From Dynamic MRI: Ac-quisition and Tracking

    E-Print Network [OSTI]

    Gilles, Benjamin

    of mechanical overload, impingement or femoral head instability. For both diagnosis and surgical planning, an acBone Motion Analysis From Dynamic MRI: Ac- quisition and Tracking INTRODUCTION Periacetabular- curate estimate of hip joint bone motion is required. Orthopedists can use animated 3D models, prior

  9. Efficient Bayesian multivariate fMRI analysis using a sparsifying spatio-temporal prior

    E-Print Network [OSTI]

    Edinburgh, University of

    Efficient Bayesian multivariate fMRI analysis using a sparsifying spatio-temporal prior Marcel A Available online 1 December 2009 Keywords: Multivariate analysis Bayesian inference Expectation propagation Laplace prior is introduced as a multivariate approach to the analysis of neuroimaging data. It is shown

  10. Spatiotemporal wavelet analysis for functional MRI Chris Long,a,* Emery N. Brown,b,c

    E-Print Network [OSTI]

    Manoach, Dara S.

    Spatiotemporal wavelet analysis for functional MRI Chris Long,a,* Emery N. Brown,b,c Dara Manoach in their statistical formulations. To address these issues, we present a novel spatiotemporal wavelet procedure that uses a stimulus-convolved hemodynamic signal plus correlated noise model. The wavelet fits, computed

  11. The development of MRI for the determination of porosity distribution in reservoir core samples

    E-Print Network [OSTI]

    Shivers, Jon Blake

    1991-01-01T23:59:59.000Z

    Sandstone appeared to be very isotropic while the Austin Chalk exhibited varying degrees of correlation in the directions considered. A comparison between the correlation of MRI derived core plug size porosity distributions and foot by foot whole core.... . Spatial Correlation of Porosity Data. . . . . . . . . . . . . . . . . . . . . . Comparison with Foot by Foot Vertical Data. . Composite Sample Distribution. . Reproducibility. . 22 , 25 . . . . 30 . . . . . 4 2 . 44 . 47 CHAPTER V ? CONCLUSIONS...

  12. EXTRACTING GEOMETRIC FEATURES OF AORTIC VALVE ANNULUS MOTION FROM DYNAMIC MRI FOR GUIDING INTERVENTIONS

    E-Print Network [OSTI]

    Deng, Zhigang

    EXTRACTING GEOMETRIC FEATURES OF AORTIC VALVE ANNULUS MOTION FROM DYNAMIC MRI FOR GUIDING, Houston, TX 77030, USA ABSTRACT Transcatheter aortic valve implant (TAVI) has emerged as a prominent of the geometric features such as the diameter, center and orien- tation of the aortic valve annulus (AVA

  13. Designing Single-and Multiple-Shell Sampling Schemes for Diffusion MRI Using Spherical Code

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    is the Electrostatic Energy Minimiza- tion (EEM) method introduced in dMRI by Jones et al. However, the electrostatic energy formulation in EEM is not directly related to the goal of optimal sampling- scheme design, i invariance than the generalized EEM (gEEM) method currently used in the Human Connectome Project (HCP). 1

  14. Studying MRI acquisition protocols of sustained sounds with a multimodal acquisition system

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    system which utilizes infrared emit- ting diodes (IREDs) requires that the sensors to be visible from a multimodal acquisition system which uses electromagnetogra- phy sensors to locate the US probe a millimetric accuracy 3D MRI images of the vocal tract have enabled more accurate evaluations of vocal tract

  15. Development/Plasticity/Repair A Structural MRI Study of Human Brain Development from

    E-Print Network [OSTI]

    Utah, University of

    Development/Plasticity/Repair A Structural MRI Study of Human Brain Development from Birth to 2 Carolina, Chapel Hill, North Carolina 27599-7510 Brain development in the first 2 years after birth and schizophrenia. Knowledge regarding this period is currently quite limited. We studied structural brain

  16. MRI-Guided Coronary Catheterization and PTCA: A Feasibility Study on a Dog Model

    E-Print Network [OSTI]

    Atalar, Ergin

    of this work was to demonstrate the feasibility of MRI-guided coronary artery catheterization and intervention- cessful catheterization. Percutaneous transluminal coronary angioplasty (PTCA) was attempted after two of percutaneous transluminal coronary angio- plasty (PTCA) guided by X-ray fluoroscopy has been ex- plosive over

  17. MRI-based Microrobotic system for the Propulsion and Navigation of Ferromagnetic Microcapsules

    E-Print Network [OSTI]

    Boyer, Edmond

    MRI-based Microrobotic system for the Propulsion and Navigation of Ferromagnetic Microcapsules 3-D navigation of a microdevice in blood ves- sels, namely: (i) vessel path planner, (ii) magnetic, magnetic resonance imaging, minimally invasive interventions, real-time control Email address: antoine

  18. COMPUTATIONAL STUDIES OF CONTROLLED NANOPARTICLE AGGLOMERATIONS FOR MRI-GUIDED NANOROBOTIC DRUG-DELIVERY SYSTEMS

    E-Print Network [OSTI]

    Mavroidis, Constantinos

    groups have employed magnetized micro/ nanoparticles and have implemented magnetic propulsion techniques implementation is difficult and medically invasive. Finally, magnetic propulsion techniques #12;other thanEastern University Boston, MA 02115 mavro@coe.neu.edu ABSTRACT Magnetic Resonance Imaging (MRI) guided nanorobotic

  19. Using multi-voxel pattern analysis of fMRI data to interpret overlapping functional activations

    E-Print Network [OSTI]

    Downing, Paul

    by the two experimental conditions (but not the respective controls). For example, this interpretation has.A. et al. (2006) Beyond mind-reading: multi-voxel pattern analysis of fMRI data. Trends Cogn. Sci. 10 di Pellegrino, G. et al. (1992) Understanding motor events: a neurophysiological study. Exp. Brain

  20. Investigation of PET/MRI Image Fusion Schemes for Enhanced Breast Cancer Diagnosis

    E-Print Network [OSTI]

    with anatomical images is well appreciated in the advent of PET/CT. There is an increasing interest in expanding. Initial experience with combined PET (functional imaging) and x-ray computed tomography (CT, anatomicalInvestigation of PET/MRI Image Fusion Schemes for Enhanced Breast Cancer Diagnosis Karl G. Baum

  1. The neural correlates of statistical learning in a word segmentation task: An fMRI study

    E-Print Network [OSTI]

    Aslin, Richard N.

    language Sequence learning Broca's area LIFG a b s t r a c t Functional magnetic resonance imaging (f of this statistical learning mechanism in the do- main of language acquisition (see also Saffran, Aslin, & NewportThe neural correlates of statistical learning in a word segmentation task: An fMRI study Elisabeth

  2. fMRI visualisation of transient activations in the rat olfactory bulb using short odour stimulations

    E-Print Network [OSTI]

    Paris-Sud XI, Université de

    fMRI visualisation of transient activations in the rat olfactory bulb using short odour in the olfactory bulb OB displays both spatial and temporal organization. The difficulty when assessing spatio of the olfactory bulb (OB). Hence, in this structure, the identity of odorants is associated with a unique spatial

  3. Saline as the Sole Contrast Agent for Successful MRI-guided Epidural Injections

    SciTech Connect (OSTI)

    Deli, Martin, E-mail: martin.deli@web.de [University of Witten/Herdecke, Department of Radiology and Microtherapy, Groenemeyer Institute for Microtherapy (GIMT) (Germany); Fritz, Jan, E-mail: jfritz9@jhmi.edu [Johns Hopkins University School of Medicine, Russell H. Morgan Department of Radiology and Radiological Science (United States); Mateiescu, Serban, E-mail: mateiescu@microtherapy.de; Busch, Martin, E-mail: busch@microtherapy.de [University of Witten/Herdecke, Department of Radiology and Microtherapy, Groenemeyer Institute for Microtherapy (GIMT) (Germany); Carrino, John A., E-mail: jcarrin2@jhmi.edu [Johns Hopkins University School of Medicine, Russell H. Morgan Department of Radiology and Radiological Science (United States); Becker, Jan, E-mail: j.becker@microtherapy.de; Garmer, Marietta, E-mail: garmer@microtherapy.de; Groenemeyer, Dietrich, E-mail: dg@microtherapy.de [University of Witten/Herdecke, Department of Radiology and Microtherapy, Groenemeyer Institute for Microtherapy (GIMT) (Germany)

    2013-06-15T23:59:59.000Z

    Purpose. To assess the performance of sterile saline solution as the sole contrast agent for percutaneous magnetic resonance imaging (MRI)-guided epidural injections at 1.5 T. Methods. A retrospective analysis of two different techniques of MRI-guided epidural injections was performed with either gadolinium-enhanced saline solution or sterile saline solution for documentation of the epidural location of the needle tip. T1-weighted spoiled gradient echo (FLASH) images or T2-weighted single-shot turbo spin echo (HASTE) images visualized the test injectants. Methods were compared by technical success rate, image quality, table time, and rate of complications. Results. 105 MRI-guided epidural injections (12 of 105 with gadolinium-enhanced saline solution and 93 of 105 with sterile saline solution) were performed successfully and without complications. Visualization of sterile saline solution and gadolinium-enhanced saline solution was sufficient, good, or excellent in all 105 interventions. For either test injectant, quantitative image analysis demonstrated comparable high contrast-to-noise ratios of test injectants to adjacent body substances with reliable statistical significance levels (p < 0.001). The mean table time was 22 {+-} 9 min in the gadolinium-enhanced saline solution group and 22 {+-} 8 min in the saline solution group (p = 0.75). Conclusion. Sterile saline is suitable as the sole contrast agent for successful and safe percutaneous MRI-guided epidural drug delivery at 1.5 T.

  4. Optimization of experimental design in fMRI: a general framework using a genetic algorithm

    E-Print Network [OSTI]

    Optimization of experimental design in fMRI: a general framework using a genetic algorithm Tor D uses a genetic algorithm (GA), a class of flexible search algorithms that optimize designs with respect with respect to fitness criteria, allowing optimization over known or novel fitness measures. We describe how

  5. Learning to Identify Overlapping and Hidden Cognitive Processes from fMRI Data

    E-Print Network [OSTI]

    Gordon, Geoffrey J.

    We define a Hidden Process Model (HPM) as a set of processes, each described by its characteristic HDRs across multiple voxels in the brain. 2.1 Learning HPMs First consider learning an HPM (i.e., the HDR for each HPM process) given fMRI data plus the known timing and identity of each process

  6. Brief Communications Attentional Modulation of fMRI Responses in Human V1 Is

    E-Print Network [OSTI]

    Song, Joo-Hyun

    for the attended features (Martinez- Trujillo and Treue, 2004). This change can be detected using fMRI (Serences et- ings (Gc or Ga), and to detect small changes in the attended dimension (Fig. 1). Regardless of the task conditions (Gc, Ga) and the two attentional tasks (AO, AC). We hypothesized that our ability to classify

  7. MRI-Visible Micellar Nanomedicine for Targeted Drug Delivery to Lung Cancer Cells

    E-Print Network [OSTI]

    Gao, Jinming

    MRI-Visible Micellar Nanomedicine for Targeted Drug Delivery to Lung Cancer Cells Jagadeesh Setti micelle (MFM) system that is encoded with a lung cancer-targeting peptide (LCP), and encapsulated. The LCP-encoded MFM showed significantly increased Rv 6-dependent cell targeting in H2009 lung cancer

  8. Comparative analysis of nonlinear dimensionality reduction techniques for breast MRI segmentation

    SciTech Connect (OSTI)

    Akhbardeh, Alireza; Jacobs, Michael A. [Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 (United States); Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 (United States) and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 (United States)

    2012-04-15T23:59:59.000Z

    Purpose: Visualization of anatomical structures using radiological imaging methods is an important tool in medicine to differentiate normal from pathological tissue and can generate large amounts of data for a radiologist to read. Integrating these large data sets is difficult and time-consuming. A new approach uses both supervised and unsupervised advanced machine learning techniques to visualize and segment radiological data. This study describes the application of a novel hybrid scheme, based on combining wavelet transform and nonlinear dimensionality reduction (NLDR) methods, to breast magnetic resonance imaging (MRI) data using three well-established NLDR techniques, namely, ISOMAP, local linear embedding (LLE), and diffusion maps (DfM), to perform a comparative performance analysis. Methods: Twenty-five breast lesion subjects were scanned using a 3T scanner. MRI sequences used were T1-weighted, T2-weighted, diffusion-weighted imaging (DWI), and dynamic contrast-enhanced (DCE) imaging. The hybrid scheme consisted of two steps: preprocessing and postprocessing of the data. The preprocessing step was applied for B{sub 1} inhomogeneity correction, image registration, and wavelet-based image compression to match and denoise the data. In the postprocessing step, MRI parameters were considered data dimensions and the NLDR-based hybrid approach was applied to integrate the MRI parameters into a single image, termed the embedded image. This was achieved by mapping all pixel intensities from the higher dimension to a lower dimensional (embedded) space. For validation, the authors compared the hybrid NLDR with linear methods of principal component analysis (PCA) and multidimensional scaling (MDS) using synthetic data. For the clinical application, the authors used breast MRI data, comparison was performed using the postcontrast DCE MRI image and evaluating the congruence of the segmented lesions. Results: The NLDR-based hybrid approach was able to define and segment both synthetic and clinical data. In the synthetic data, the authors demonstrated the performance of the NLDR method compared with conventional linear DR methods. The NLDR approach enabled successful segmentation of the structures, whereas, in most cases, PCA and MDS failed. The NLDR approach was able to segment different breast tissue types with a high accuracy and the embedded image of the breast MRI data demonstrated fuzzy boundaries between the different types of breast tissue, i.e., fatty, glandular, and tissue with lesions (>86%). Conclusions: The proposed hybrid NLDR methods were able to segment clinical breast data with a high accuracy and construct an embedded image that visualized the contribution of different radiological parameters.

  9. SU-D-9A-03: STAMP: Simulator for Texture Analysis in MRI/PET

    SciTech Connect (OSTI)

    Laberge, S; Vallieres, M; Levesque, I R.; El Naqa, I [McGill University, Montreal, QC (Canada)

    2014-06-01T23:59:59.000Z

    Purpose: To develop a convenient simulation platform to facilitate PET/MR image analysis with the prospect of gaining a better understanding of the influence of acquisition parameters on PET/MRI textural features. The simulation platform is demonstrated by showing textural variations of a representative case study using different image acquisition parameters. Methods: The simulation platform is composed of MRI simulators JEMRIS and SIMRI to achieve simulations of customized MRI sequences on sample tumor models. The PET simulator GATE is used to get 2D and 3D Monte Carlo acquisitions of voxelized PET sources using a phantom geometry and a customized scanner architecture. The platform incorporates a series of graphical user interfaces written in Matlab. Two GUIs are used to facilitate communication with the simulation executables installed on a computer cluster. A third GUI is used to collect and display the clinical and simulated images, as well as fused PET/MRI images, and perform computation of textural features.To illustrate the capabilities of this platform, one FDG-PET and T1-weighted (T1w) digitized tumor models were generated from clinical images of a soft-tissue sarcoma patient. Numerically simulated MR images were produced using 3 different echo times (TE) and 5 different repetition times (TR). PET 2D images were simulated using an OSEM algorithm with 1 to 32 iterations and a post-reconstruction Gaussian filter of 0, 2, 4 or 6 mm width. Results: STAMP was successfully used to produce numerically simulated FDG-PET and MRI images, and to calculate their corresponding textures. Three typical textures (GLCM-Contrast, GLSZM-ZSV and NGTDM-Coarseness) were found to vary by a range of 45% on average compared to reference scanning conditions in the case of FDG-PET, and by a range of 40% in the case of T1w MRI. Conclusion: We have successfully developed a Matlab-based simulation platform to facilitate PET/MRI texture image analysis for outcome prediction.

  10. Research Statement

    E-Print Network [OSTI]

    2015-01-18T23:59:59.000Z

    entries in the natural numbers, into an undergraduate research project. ..... and developing the undergraduate research project described at the end of Section 2,

  11. A national laboratory of the U.S. Department of Energy Office of Energy Efficiency & Renewable Energy

    E-Print Network [OSTI]

    Renewable Energy Laboratory Technical Report NREL/TP-560-41655 March 2008 NREL is operated by Midwest.S. Department of Energy Office of Energy Efficiency and Renewable Energy by Midwest Research InstituteA national laboratory of the U.S. Department of Energy Office of Energy Efficiency & Renewable

  12. Emerging Markets for Renewable Energy Certificates

    E-Print Network [OSTI]

    .nrel.gov Operated for the U.S. Department of Energy Office of Energy Efficiency and Renewable Energy by Midwest.S. Department of Energy Office of Energy Efficiency and Renewable Energy by Midwest Research InstituteEmerging Markets for Renewable Energy Certificates: Opportunities and Challenges January 2005

  13. Investigation of Cryo-Cooled Microcoils for MRI

    E-Print Network [OSTI]

    Godley, Richard Franklin

    2012-10-19T23:59:59.000Z

    with interdigitated finger capacitors. 11 1 1 2. PLANAR PAIR COILS 2.1 Introduction In fall 2010, the project was in its later stages. At that time, work was ongoing on cooling planar pair coils used by our research group for an imaging technique...

  14. 4D tumor centroid tracking using orthogonal 2D dynamic MRI: Implications for radiotherapy planning

    SciTech Connect (OSTI)

    Tryggestad, Erik [Department of Radiation Oncology and Molecular Radiation Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231 and Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota 55905 (United States)] [Department of Radiation Oncology and Molecular Radiation Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231 and Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota 55905 (United States); Flammang, Aaron; Shea, Steven M. [Center for Applied Medical Imaging, Siemens Corporation, Corporate Technology, Baltimore, Maryland 21205 (United States)] [Center for Applied Medical Imaging, Siemens Corporation, Corporate Technology, Baltimore, Maryland 21205 (United States); Hales, Russell; Herman, Joseph; Lee, Junghoon; McNutt, Todd; Roland, Teboh; Wong, John [Department of Radiation Oncology and Molecular Radiation Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231 (United States)] [Department of Radiation Oncology and Molecular Radiation Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231 (United States)

    2013-09-15T23:59:59.000Z

    Purpose: Current pretreatment, 4D imaging techniques are suboptimal in that they sample breathing motion over a very limited “snapshot” in time. Heretofore, long-duration, 4D motion characterization for radiotherapy planning, margin optimization, and validation have been impractical for safety reasons, requiring invasive markers imaged under x-ray fluoroscopy. To characterize 3D tumor motion and associated variability over durations more consistent with treatments, the authors have developed a practical dynamic MRI (dMRI) technique employing two orthogonal planes acquired in a continuous, interleaved fashion.Methods: 2D balanced steady-state free precession MRI was acquired continuously over 9–14 min at approximately 4 Hz in three healthy volunteers using a commercial 1.5 T system; alternating orthogonal imaging planes (sagittal, coronal, sagittal, etc.) were employed. The 2D in-plane pixel resolution was 2 × 2 mm{sup 2} with a 5 mm slice profile. Simultaneous with image acquisition, the authors monitored a 1D surrogate respiratory signal using a device available with the MRI system. 2D template matching-based anatomic feature registration, or tracking, was performed independently in each orientation. 4D feature tracking at the raw frame rate was derived using spline interpolation.Results: Tracking vascular features in the lung for two volunteers and pancreatic features in one volunteer, the authors have successfully demonstrated this method. Registration error, defined here as the difference between the sagittal and coronal tracking result in the SI direction, ranged from 0.7 to 1.6 mm (1?) which was less than the acquired image resolution. Although the healthy volunteers were instructed to relax and breathe normally, significantly variable respiration was observed. To demonstrate potential applications of this technique, the authors subsequently explored the intrafraction stability of hypothetical tumoral internal target volumes and 3D spatial probability distribution functions. The surrogate respiratory information allowed the authors to show how this technique can be used to study correlations between internal and external (surrogate) information over these prolonged durations. However, compared against the gold standard of the time stamps in the dMRI frames, the temporal synchronization of the surrogate 1D respiratory information was shown to be likely unreliable.Conclusions: The authors have established viability of a novel and practical pretreatment, 4D tumor centroid tracking method employing a commercially available dynamic MRI sequence. Further developments from the vendor are likely needed to provide a reliably synchronized surrogate 1D respiratory signal, which will likely broaden the utility of this method in the pretreatment radiotherapy planning context.

  15. The cortical organization of audio-visual sentence comprehension: an fMRI study at 4 Tesla

    E-Print Network [OSTI]

    The cortical organization of audio-visual sentence comprehension: an fMRI study at 4 Tesla Cheryl M Tesla. Participants viewed the face and upper body of a speaker via a video screen while listening

  16. High-resolution 18F-FDG PET with MRI for monitoring response to treatment in rheumatoid arthritis

    E-Print Network [OSTI]

    2010-01-01T23:59:59.000Z

    of a dedicated breast PET/CT scanner during human imaging. Jhigh-resolution 18 F-FDG PET images (pseudocolor) overlaidMONTH High-resolution 18 F-FDG PET with MRI for monitoring

  17. Adaptive processing of thin structures to augment segmentation of dual-channel structural MRI of the human brain 

    E-Print Network [OSTI]

    Withers, James

    2010-01-01T23:59:59.000Z

    This thesis presents a method for the segmentation of dual-channel structural magnetic resonance imaging (MRI) volumes of the human brain into four tissue classes. The state-of-the-art FSL FAST segmentation software ...

  18. Detection power, temporal response, and spatial resolution of IRON fMRI in awake, behaving monkeys at 3 Tesla

    E-Print Network [OSTI]

    Leite, Francisca Maria Pais Horta

    2007-01-01T23:59:59.000Z

    The main goal of this thesis was to systematically characterize the detection sensitivity, temporal response, and spatial resolution of IRON contrast for fMRI within the awake, behaving monkey. Understanding these issues ...

  19. Postdoctoral Research Awards Annual Research Meeting: Joseph...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Joseph Mondloch Postdoctoral Research Awards Annual Research Meeting: Joseph Mondloch Postdoctoral Research Awards Annual Research Meeting: Joseph Mondloch poster presentation....

  20. Evaluation of potential internal target volume of liver tumors using cine-MRI

    SciTech Connect (OSTI)

    Akino, Yuichi, E-mail: akino@radonc.med.osaka-u.ac.jp [Department of Radiation Oncology, Osaka University Graduate School of Medicine, Suita, Osaka 5650871, Japan and Miyakojima IGRT Clinic, Miyakojima-ku, Osaka 5340021 (Japan); Oh, Ryoong-Jin; Masai, Norihisa; Shiomi, Hiroya; Inoue, Toshihiko [Miyakojima IGRT Clinic, Miyakojima-ku, Osaka 5340021 (Japan)

    2014-11-01T23:59:59.000Z

    Purpose: Four-dimensional computed tomography (4DCT) is widely used for evaluating moving tumors, including lung and liver cancers. For patients with unstable respiration, however, the 4DCT may not visualize tumor motion properly. High-speed magnetic resonance imaging (MRI) sequences (cine-MRI) permit direct visualization of respiratory motion of liver tumors without considering radiation dose exposure to patients. Here, the authors demonstrated a technique for evaluating internal target volume (ITV) with consideration of respiratory variation using cine-MRI. Methods: The authors retrospectively evaluated six patients who received stereotactic body radiotherapy (SBRT) to hepatocellular carcinoma. Before acquiring planning CT, sagittal and coronal cine-MRI images were acquired for 30 s with a frame rate of 2 frames/s. The patient immobilization was conducted under the same condition as SBRT. Planning CT images were then acquired within 15 min from cine-MRI image acquisitions, followed by a 4DCT scan. To calculate tumor motion, the motion vectors between two continuous frames of cine-MRI images were calculated for each frame using the pyramidal Lucas–Kanade method. The target contour was delineated on one frame, and each vertex of the contour was shifted and copied onto the following frame using neighboring motion vectors. 3D trajectory data were generated with the centroid of the contours on sagittal and coronal images. To evaluate the accuracy of the tracking method, the motion of clearly visible blood vessel was analyzed with the motion tracking and manual detection techniques. The target volume delineated on the 50% (end-exhale) phase of 4DCT was translated with the trajectory data, and the distribution of the occupancy probability of target volume was calculated as potential ITV (ITV {sub Potential}). The concordance between ITV {sub Potential} and ITV estimated with 4DCT (ITV {sub 4DCT}) was evaluated using the Dice’s similarity coefficient (DSC). Results: The distance between blood vessel positions determined with motion tracking and manual detection was analyzed. The mean and SD of the distance were less than 0.80 and 0.52 mm, respectively. The maximum ranges of tumor motion on cine-MRI were 2.4 ± 1.4 mm (range, 1.0–5.0 mm), 4.4 ± 3.3 mm (range, 0.8–9.4 mm), and 14.7 ± 5.9 mm (range, 7.4–23.4 mm) in lateral, anterior–posterior, and superior–inferior directions, respectively. The ranges in the superior–inferior direction were larger than those estimated with 4DCT images for all patients. The volume of ITV {sub Potential} was 160.3% ± 13.5% (range, 142.0%–179.2%) of the ITV {sub 4DCT}. The maximum DSC values were observed when the cutoff value of 24.7% ± 4.0% (range, 20%–29%) was applied. Conclusions: The authors demonstrated a novel method of calculating 3D motion and ITV {sub Potential} of liver cancer using orthogonal cine-MRI. Their method achieved accurate calculation of the respiratory motion of moving structures. Individual evaluation of the ITV {sub Potential} will aid in improving respiration management and treatment planning.

  1. MINERnA Introduction, Detector Progress and MRI Proposal

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > The EnergyCenter (LMI-EFRC) - CenterLinksLow

  2. Progress on detection of liquid explosives using ultra-low field MRI

    SciTech Connect (OSTI)

    Espy, Michelle A [Los Alamos National Laboratory; Matlashov, Andrei N [Los Alamos National Laboratory; Volegov, Petr L [Los Alamos National Laboratory; Schuttz, Larry M [Los Alamos National Laboratory; Baguisa, Shermiyah [Los Alamos National Laboratory; Dunkerley, David [Los Alamos National Laboratory; Magnelind, Per [Los Alamos National Laboratory; Owens, Tuba [Los Alamos National Laboratory; Sandin, Henrik [Los Alamos National Laboratory; Urbaitis, Algis [Los Alamos National Laboratory

    2010-01-01T23:59:59.000Z

    Nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) methods are widely used in medicine, chemistry and industry. Over the past several years there has been increasing interest in performing NMR and MRI in the ultra-low field (ULF) regime, with measurement field strengths of 10-100 microTesla and pre-polarization fields of 30-50 mTesla. The real-time signal-to-noise ratio for such measurements is about 100. Our group at LANL has built and demonstrated the performance of SQUID-based ULF NMR/MRI instrumentation for classification of materials and detection of liquid explosives via their relaxation properties measured at ULF, using T{sub 1}, and T{sub 2}, and T{sub 1} frequency dispersion. We are also beginning to investigate the performance of induction coils as sensors. Here we present recent progress on the applications of ULF MR to the detection of liquid explosives, in imaging and relaxometry.

  3. Microbiological Research ] (

    E-Print Network [OSTI]

    Sims, Gerald K.

    ) or to expand on previous research addressing the fate of nitrogen from agrochemicals (Bichat et al., 1999

  4. High spatial resolution brain functional MRI using submillimeter balanced steady-state free precession acquisition

    SciTech Connect (OSTI)

    Wu, Pei-Hsin; Chung, Hsiao-Wen [Department of Electrical Engineering, National Taiwan University, Taipei 10617, Taiwan (China)] [Department of Electrical Engineering, National Taiwan University, Taipei 10617, Taiwan (China); Tsai, Ping-Huei [Imaging Research Center, Taipei Medical University, Taipei 11031, Taiwan and Department of Medical Imaging, Taipei Medical University Hospital, Taipei Medical University, Taipei 11031, Taiwan (China)] [Imaging Research Center, Taipei Medical University, Taipei 11031, Taiwan and Department of Medical Imaging, Taipei Medical University Hospital, Taipei Medical University, Taipei 11031, Taiwan (China); Wu, Ming-Long, E-mail: minglong.wu@csie.ncku.edu.tw [Institute of Medical Informatics, National Cheng-Kung University, Tainan 70101, Taiwan and Department of Computer Science and Information Engineering, National Cheng-Kung University, Tainan 70101, Taiwan (China)] [Institute of Medical Informatics, National Cheng-Kung University, Tainan 70101, Taiwan and Department of Computer Science and Information Engineering, National Cheng-Kung University, Tainan 70101, Taiwan (China); Chuang, Tzu-Chao [Department of Electrical Engineering, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan (China)] [Department of Electrical Engineering, National Sun Yat-Sen University, Kaohsiung 80424, Taiwan (China); Shih, Yi-Yu [Siemens Limited Healthcare Sector, Taipei 11503, Taiwan (China)] [Siemens Limited Healthcare Sector, Taipei 11503, Taiwan (China); Huang, Teng-Yi [Department of Electrical Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan (China)] [Department of Electrical Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan (China)

    2013-12-15T23:59:59.000Z

    Purpose: One of the technical advantages of functional magnetic resonance imaging (fMRI) is its precise localization of changes from neuronal activities. While current practice of fMRI acquisition at voxel size around 3 × 3 × 3 mm{sup 3} achieves satisfactory results in studies of basic brain functions, higher spatial resolution is required in order to resolve finer cortical structures. This study investigated spatial resolution effects on brain fMRI experiments using balanced steady-state free precession (bSSFP) imaging with 0.37 mm{sup 3} voxel volume at 3.0 T. Methods: In fMRI experiments, full and unilateral visual field 5 Hz flashing checkerboard stimulations were given to healthy subjects. The bSSFP imaging experiments were performed at three different frequency offsets to widen the coverage, with functional activations in the primary visual cortex analyzed using the general linear model. Variations of the spatial resolution were achieved by removing outerk-space data components. Results: Results show that a reduction in voxel volume from 3.44 × 3.44 × 2 mm{sup 3} to 0.43 × 0.43 × 2 mm{sup 3} has resulted in an increase of the functional activation signals from (7.7 ± 1.7)% to (20.9 ± 2.0)% at 3.0 T, despite of the threefold SNR decreases in the original images, leading to nearly invariant functional contrast-to-noise ratios (fCNR) even at high spatial resolution. Activation signals aligning nicely with gray matter sulci at high spatial resolution would, on the other hand, have possibly been mistaken as noise at low spatial resolution. Conclusions: It is concluded that the bSSFP sequence is a plausible technique for fMRI investigations at submillimeter voxel widths without compromising fCNR. The reduction of partial volume averaging with nonactivated brain tissues to retain fCNR is uniquely suitable for high spatial resolution applications such as the resolving of columnar organization in the brain.

  5. Electron contamination modeling and reduction in a 1 T open bore inline MRI-linac system

    SciTech Connect (OSTI)

    Oborn, B. M. [Illawarra Cancer Care Centre (ICCC), Wollongong, NSW 2500, Australia and Centre for Medical Radiation Physics (CMRP), University of Wollongong, Wollongong, NSW 2500 (Australia)] [Illawarra Cancer Care Centre (ICCC), Wollongong, NSW 2500, Australia and Centre for Medical Radiation Physics (CMRP), University of Wollongong, Wollongong, NSW 2500 (Australia); Kolling, S. [Sydney Medical School, University of Sydney, NSW 2006 (Australia)] [Sydney Medical School, University of Sydney, NSW 2006 (Australia); Metcalfe, P. E. [Centre for Medical Radiation Physics (CMRP), University of Wollongong, Wollongong, NSW 2500, Australia and Ingham Institute for Applied Medical Research, Liverpool, NSW 2170 (Australia)] [Centre for Medical Radiation Physics (CMRP), University of Wollongong, Wollongong, NSW 2500, Australia and Ingham Institute for Applied Medical Research, Liverpool, NSW 2170 (Australia); Crozier, S. [School of Information Technology and Electric Engineering, University of Queensland, QLD 4072 (Australia)] [School of Information Technology and Electric Engineering, University of Queensland, QLD 4072 (Australia); Litzenberg, D. W. [Department of Radiation Oncology, University of Michigan Hospital and Health Systems, Ann Arbor, Michigan 48109 (United States)] [Department of Radiation Oncology, University of Michigan Hospital and Health Systems, Ann Arbor, Michigan 48109 (United States); Keall, P. J. [Sydney Medical School, University of Sydney, NSW 2006, Australia and Ingham Institute for Applied Medical Research, Liverpool, NSW 2170 (Australia)] [Sydney Medical School, University of Sydney, NSW 2006, Australia and Ingham Institute for Applied Medical Research, Liverpool, NSW 2170 (Australia)

    2014-05-15T23:59:59.000Z

    Purpose: A potential side effect of inline MRI-linac systems is electron contamination focusing causing a high skin dose. In this work, the authors reexamine this prediction for an open bore 1 T MRI system being constructed for the Australian MRI-Linac Program. The efficiency of an electron contamination deflector (ECD) in purging electron contamination from the linac head is modeled, as well as the impact of a helium gas region between the deflector and phantom surface for lowering the amount of air-generated contamination. Methods: Magnetic modeling of the 1 T MRI was used to generate 3D magnetic field maps both with and without the presence of an ECD located immediately below the MLC’s. Forty-seven different ECD designs were modeled and for each the magnetic field map was imported into Geant4 Monte Carlo simulations including the linac head, ECD, and a 30 × 30 × 30 cm{sup 3} water phantom located at isocenter. For the first generation system, the x-ray source to isocenter distance (SID) will be 160 cm, resulting in an 81.2 cm long air gap from the base of the ECD to the phantom surface. The first 71.2 cm was modeled as air or helium gas, with the latter encased between two windows of 50 ?m thick high density polyethlyene. 2D skin doses (at 70 ?m depth) were calculated across the phantom surface at 1 × 1 mm{sup 2} resolution for 6 MV beams of field size of 5 × 5, 10 × 10, and 20 × 20 cm{sup 2}. Results: The skin dose was predicted to be of similar magnitude as the generic systems modeled in previous work, 230% to 1400% ofD {sub max} for 5 × 5 to 20 × 20 cm{sup 2}, respectively. Inclusion of the ECD introduced a nonuniformity to the MRI imaging field that ranged from ?20 to ?140 ppm while the net force acting on the ECD ranged from ?151 N to ?1773 N. Various ECD designs were 100% efficient at purging the electron contamination into the ECD magnet banks; however, a small percentage were scattered back into the beam and continued to the phantom surface. Replacing a large portion of the extended air-column between the ECD and phantom surface with helium gas is a key element as it significantly minimized the air-generated contamination. When using an optimal ECD and helium gas region, the 70 ?m skin dose is predicted to increase moderately inside a small hot spot over that of the case with no magnetic field present for the jaw defined square beams examined here. These increases include from 12% to 40% of D {sub max} for 5 × 5 cm{sup 2}, 18% to 55% of D {sub max} for 10 × 10 cm{sup 2}, and from 23% to 65% of D {sub max} for 20 × 20 cm{sup 2}. Conclusions: Coupling an efficient ECD and helium gas region below the MLCs in the 160 cm isocenter MRI-linac system is predicted to ameliorate the impact electron contamination focusing has on skin dose increases. An ECD is practical as its impact on the MRI imaging distortion is correctable, and the mechanical forces acting on it manageable from an engineering point of view.

  6. Concurrent segmentation of the prostate on MRI and CT via linked statistical shape models for radiotherapy planning

    SciTech Connect (OSTI)

    Chowdhury, Najeeb; Toth, Robert; Chappelow, Jonathan; Kim, Sung; Motwani, Sabin; Punekar, Salman; Lin Haibo; Both, Stefan; Vapiwala, Neha; Hahn, Stephen; Madabhushi, Anant

    2012-04-15T23:59:59.000Z

    Purpose: Prostate gland segmentation is a critical step in prostate radiotherapy planning, where dose plans are typically formulated on CT. Pretreatment MRI is now beginning to be acquired at several medical centers. Delineation of the prostate on MRI is acknowledged as being significantly simpler to perform, compared to delineation on CT. In this work, the authors present a novel framework for building a linked statistical shape model (LSSM), a statistical shape model (SSM) that links the shape variation of a structure of interest (SOI) across multiple imaging modalities. This framework is particularly relevant in scenarios where accurate boundary delineations of the SOI on one of the modalities may not be readily available, or difficult to obtain, for training a SSM. In this work the authors apply the LSSM in the context of multimodal prostate segmentation for radiotherapy planning, where the prostate is concurrently segmented on MRI and CT. Methods: The framework comprises a number of logically connected steps. The first step utilizes multimodal registration of MRI and CT to map 2D boundary delineations of the prostate from MRI onto corresponding CT images, for a set of training studies. Hence, the scheme obviates the need for expert delineations of the gland on CT for explicitly constructing a SSM for prostate segmentation on CT. The delineations of the prostate gland on MRI and CT allows for 3D reconstruction of the prostate shape which facilitates the building of the LSSM. In order to perform concurrent prostate MRI and CT segmentation using the LSSM, the authors employ a region-based level set approach where the authors deform the evolving prostate boundary to simultaneously fit to MRI and CT images in which voxels are classified to be either part of the prostate or outside the prostate. The classification is facilitated by using a combination of MRI-CT probabilistic spatial atlases and a random forest classifier, driven by gradient and Haar features. Results: The authors acquire a total of 20 MRI-CT patient studies and use the leave-one-out strategy to train and evaluate four different LSSMs. First, a fusion-based LSSM (fLSSM) is built using expert ground truth delineations of the prostate on MRI alone, where the ground truth for the gland on CT is obtained via coregistration of the corresponding MRI and CT slices. The authors compare the fLSSM against another LSSM (xLSSM), where expert delineations of the gland on both MRI and CT are employed in the model building; xLSSM representing the idealized LSSM. The authors also compare the fLSSM against an exclusive CT-based SSM (ctSSM), built from expert delineations of the gland on CT alone. In addition, two LSSMs trained using trainee delineations (tLSSM) on CT are compared with the fLSSM. The results indicate that the xLSSM, tLSSMs, and the fLSSM perform equivalently, all of them out-performing the ctSSM. Conclusions: The fLSSM provides an accurate alternative to SSMs that require careful expert delineations of the SOI that may be difficult or laborious to obtain. Additionally, the fLSSM has the added benefit of providing concurrent segmentations of the SOI on multiple imaging modalities.

  7. SU-E-J-144: MRI Visualization of a Metallic Fiducial Marker Used for Image Guided Prostate Radiotherapy

    SciTech Connect (OSTI)

    Yee, S; Krauss, D; Yan, D [William Beaumont Hospital, Royal Oak, MI (United States)

    2014-06-01T23:59:59.000Z

    Purpose: Unlike on the daily CBCT used for the image-guided radiation therapy, the visualization of an implantable metallic fiducial marker on the planning MRI images has been a challenge due to the inherent insensitivity of metal in MRI, and very thin (? 1 mm or less) diameter. Here, an MRI technique to visualize a marker used for prostate cancer radiotherapy is reported. Methods: During the MRI acquisitions, a multi-shot turbo spin echo (TSE) technique (TR=3500 ms, TE=8.6 ms, ETL=17, recon voxel=0.42x0.42x3.5 mm3) was acquired in Philips 3T Ingenia together with a T2-weighted multi-shot TSE (TR=5381 ms, TE=110 ms, ETL=17, recon voxel=0.47×0.47×3 mm3) and a balanced turbo field echo (bTFE, flip angle 60, TR=2.76 ms, TE=1.3 ms, 0.85×0.85×3 mm3, NSA=4). In acquiring the MRI to visualize the fiducial marker, a particular emphasis was made to improve the spatial resolution and visibility in the generally dark, inhomogeneous prostate area by adjusting the slice profile ordering and TE values of TSE acquisition (in general, the lower value of TE in TSE acquisition generates a brighter signal but at the cost of high spatial resolution since the k-space, responsible for high spatial resolution, is filled with noisier data). Results: While clearly visible in CT, the marker was not visible in either T2-weighted TSE or bTFE, although the image qualities of both images were superior. In the new TSE acquisition (? a proton-density weighted image) adjusted by changing the profile ordering and the TE value, the marker was visible as a negative (but clear) contrast in the magnitude MRI, and as a positive contrast in the imaginary image of the phase-sensitive MRI. Conclusion: A metallic fiducial marker used for image guidance before prostate cancer radiotherapy can be made visible in MRI, which may facilitate more use of MRI in planning and guiding such radiation therapy.

  8. Research Gallery

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Environmental Monitoring and Research Nanotechnology: The Science of the Small Algae to Biofuels: Squeezing Power from Pond Scum Living with Wildfire: A Shared Community...

  9. How MRI Compatible is 'MRI Compatible'? A Systematic Comparison of Artifacts Caused by Biopsy Needles at 3.0 and 1.5 T

    SciTech Connect (OSTI)

    Penzkofer, Tobias, E-mail: tpenzkofer@ukaachen.de [RWTH Aachen University Hospital, Department of Diagnostic and Interventional Radiology (Germany)] [RWTH Aachen University Hospital, Department of Diagnostic and Interventional Radiology (Germany); Peykan, Nilufar [Klinikum Osnabrueck, Roentgen- und Strahlenklinik (Germany)] [Klinikum Osnabrueck, Roentgen- und Strahlenklinik (Germany); Schmidt, Katja [RWTH Aachen University Hospital, Department of Diagnostic and Interventional Radiology (Germany)] [RWTH Aachen University Hospital, Department of Diagnostic and Interventional Radiology (Germany); Krombach, Gabriele [Justus-Liebig University Giessen, Department of Radiology (Germany)] [Justus-Liebig University Giessen, Department of Radiology (Germany); Kuhl, Christiane K. [RWTH Aachen University Hospital, Department of Diagnostic and Interventional Radiology (Germany)] [RWTH Aachen University Hospital, Department of Diagnostic and Interventional Radiology (Germany)

    2013-12-15T23:59:59.000Z

    Purpose: This study was designed to systematically investigate artifacts caused by interventional needles recommended for use in MRI, with focus on field strength, needle/mandrin type, orientation and sequence. Methods: Eight different MRI compatible needles were placed in porcine tissue and examined at 1.5 and 3.0 T with balanced-steady-state-free-precession (B-SSFP) and T1-weighted-spoiled-gradient-echo (T1-SPGR) sequences in different orientations to B{sub 0}. Artifact diameters with regards to the primary, inner, and secondary, outer artifacts were assessed and statistically evaluated. Results: The types and degree of artifacts varied considerably, especially between different mandrin types even for the same needles. Orientation of the needle in the magnetic field was another main contributor to the artifact dimensions. Less important factors were the type of pulse sequence and field strength. Artifacts ranged from 0.7 mm (steel, 0 Degree-Sign , B-SSFP, 3.0 T, inner) to 71.4 mm (nitinol, 90 Degree-Sign , B-SSFP, 1.5 T, outer). Inner artifact diameters in B-SSFP were slightly larger (8.2 {+-} 5.7 mm) than those in T1-SPGR (7.6 {+-} 5.4 mm) and comparable between 1.5 and 3.0 T (e.g., 8.0 vs. 8.4 mm, B-SSFP). Conclusions: Although all were sold as 'MR compatible,' the artifacts differed greatly between needle types, and even more so for different mandrins. The results suggest an empirical approach to the needle choice based on lesion type and approach angle.

  10. RESEARCH ARTICLE Community structure and differential responses of aquatic

    E-Print Network [OSTI]

    Swihart, Robert K. "Rob"

    , pollution, sedimentation, introduced species, or altered hydrology (Johnson et al. 2002). Modeling of future. The occurrence and abundance of several species also were modeled to test hypotheses regarding the importance an agricultural landscape of the Midwest. The ability of aquatic turtles to disperse in a frag- mented landscape

  11. Researchers, Appointments

    E-Print Network [OSTI]

    in Aviation Gas Turbine Combustion/Emissions Research and Design System Optimization (UTIAS) Luca ScardoviInnovative Researchers, Devoted Educators Academic Appointments 2009­2012 #12;Innovative is a centre of immense inspiration, remarkable innovation and endless possibilities. And since 2009, we have

  12. Postdoctoral Research Awards Annual Research Meeting: Padmaja...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Padmaja Gunda Postdoctoral Research Awards Annual Research Meeting: Padmaja Gunda Poster Presentation at 2012 EERE Annual Research Meeting, Postdoctoral Research Awards, from the...

  13. Postdoctoral Research Awards Annual Research Meeting: Brandon...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Brandon Mercado Postdoctoral Research Awards Annual Research Meeting: Brandon Mercado Poster Presentation at 2012 EERE Annual Research Meeting, Postdoctoral Research Awards, from...

  14. Apparatus for preparing a solution of a hyperpolarized noble gas for NMR and MRI analysis

    DOE Patents [OSTI]

    Pines, Alexander (Berkeley, CA); Budinger, Thomas (Berkeley, CA); Navon, Gil (Ramat Gan, IL); Song, Yi-Qiao (Berkeley, CA); Appelt, Stephan (Waiblingen, DE); Bifone, Angelo (Rome, IT); Taylor, Rebecca (Berkeley, CA); Goodson, Boyd (Berkeley, CA); Seydoux, Roberto (Berkeley, CA); Room, Toomas (Albany, CA); Pietrass, Tanja (Socorro, NM)

    2008-06-10T23:59:59.000Z

    The present invention relates generally to nuclear magnetic resonance (NMR) techniques for both spectroscopy and imaging. More particularly, the present invention relates to methods in which hyperpolarized noble gases (e.g., Xe and He) are used to enhance and improve NMR and MRI. Additionally, the hyperpolarized gas solutions of the invention are useful both in vitro and in vivo to study the dynamics or structure of a system. When used with biological systems, either in vivo or in vitro, it is within the scope of the invention to target the hyperpolarized gas and deliver it to specific regions within the system.

  15. Dosimetric feasibility of real-time MRI-guided proton therapy

    SciTech Connect (OSTI)

    Moteabbed, M., E-mail: mmoteabbed@partners.org; Schuemann, J.; Paganetti, H. [Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114 (United States)

    2014-11-01T23:59:59.000Z

    Purpose: Magnetic resonance imaging (MRI) is a prime candidate for image-guided radiotherapy. This study was designed to assess the feasibility of real-time MRI-guided proton therapy by quantifying the dosimetric effects induced by the magnetic field in patients’ plans and identifying the associated clinical consequences. Methods: Monte Carlo dose calculation was performed for nine patients of various treatment sites (lung, liver, prostate, brain, skull-base, and spine) and tissue homogeneities, in the presence of 0.5 and 1.5 T magnetic fields. Dose volume histogram (DVH) parameters such as D{sub 95}, D{sub 5}, and V{sub 20} as well as equivalent uniform dose were compared for the target and organs at risk, before and after applying the magnetic field. The authors further assessed whether the plans affected by clinically relevant dose distortions could be corrected independent of the planning system. Results: By comparing the resulting dose distributions and analyzing the respective DVHs, it was determined that despite the observed lateral beam deflection, for magnetic fields of up to 0.5 T, neither was the target coverage jeopardized nor was the dose to the nearby organs increased in all cases except for prostate. However, for a 1.5 T magnetic field, the dose distortions were more pronounced and of clinical concern in all cases except for spine. In such circumstances, the target was severely underdosed, as indicated by a decrease in D{sub 95} of up to 41% of the prescribed dose compared to the nominal situation (no magnetic field). Sites such as liver and spine were less affected due to higher tissue homogeneity, typically smaller beam range, and the choice of beam directions. Simulations revealed that small modifications to certain plan parameters such as beam isocenter (up to 19 mm) and gantry angle (up to 10°) are sufficient to compensate for the magnetic field-induced dose disturbances. The authors’ observations indicate that the degree of required corrections strongly depends on the beam range and direction relative to the magnetic field. This method was also applicable to more heterogeneous scenarios such as skull-base tumors. Conclusions: This study confirmed the dosimetric feasibility of real-time MRI-guided proton therapy and delivering a clinically acceptable dose to patients with various tumor locations within magnetic fields of up to 1.5 T. This work could serve as a guide and encouragement for further efforts toward clinical implementation of hybrid MRI–proton gantry systems.

  16. Enhancement of NMR and MRI in the presence of hyperpolarized noble gases

    DOE Patents [OSTI]

    Pines, Alexander; Budinger, Thomas; Navon, Gil; Song, Yi-Qiao; Appelt, Stephan; Bifone, Angelo; Taylor, Rebecca; Goodson, Boyd; Seydoux, Roberto; Room, Toomas; Pietrass, Tanja

    2004-11-16T23:59:59.000Z

    The present invention relates generally to nuclear magnetic resonance (NMR) techniques for both spectroscopy and imaging. More particularly, the present invention relates to methods in which hyperpolarized noble gases (e.g., Xe and He) are used to enhance and improve NMR and MRI. Additionally, the hyperpolarized gas solutions of the invention are useful both in vitro and in vivo to study the dynamics or structure of a system. When used with biological systems, either in vivo or in vitro, it is within the scope of the invention to target the hyperpolarized gas and deliver it to specific regions within the system.

  17. Portable MRI could aid wounded soldiers and children in the Third World

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Science (SC)IntegratedSpeeding accessPeptoidLabPhysicsPits |RegulationsPortable MRI could aid

  18. Approaches to Creating and Controlling Motion in MRI Gregory S. Fischer, Member, IEEE, Gregory Cole, Student Member, IEEE and Hao Su, Student Member, IEEE

    E-Print Network [OSTI]

    Camesano, Terri

    Approaches to Creating and Controlling Motion in MRI Gregory S. Fischer, Member, IEEE, Gregory Cole, Student Member, IEEE and Hao Su, Student Member, IEEE Abstract-- Magnetic Resonance Imaging (MRI) can is complicated by factors including: the high magnetic field strength, the requirement that such devices should

  19. The use of MRI to observe fractures in concrete E. Marfisi*, C. J. Burgoyne*, M. H. G. Amin and L. D. Hall

    E-Print Network [OSTI]

    Burgoyne, Chris

    of aggregate can clearly be seen. The third paper 2 reports on the testing of a rein- forced concrete beamThe use of MRI to observe fractures in concrete E. Marfisi*, C. J. Burgoyne*, M. H. G. Amin and L resonance imaging (MRI) of water allows the internal crack pattern of hardened concrete to be observed along

  20. The MagLab's ultra-wide-bore (105mm) 21.1T NMR/MRI magnet provides an opportunity to use low gamma, low

    E-Print Network [OSTI]

    McQuade, D. Tyler

    The MagLab's ultra-wide-bore (105mm) 21.1T NMR/MRI magnet provides an opportunity to use low gamma, low sensitive nuclei for MR imaging. The potential of nuclei such as chlorine remains largely and the capability of MRI at ultra high magnetic fields to observe glioma. The finding of an increased concentration

  1. Interactive Virtual Probing of 4D MRI Blood-Flow Roy van Pelt, Javier Olivan Bescos, Marcel Breeuwer, Rachel E. Clough,

    E-Print Network [OSTI]

    Interactive Virtual Probing of 4D MRI Blood-Flow Roy van Pelt, Javier Oliv´an Besc´os, Marcel of cardiovascular 4D MRI blood-flow data. Color in the leftmost rendition encodes the blood-flow vorticity, while color in other renditions conveys the local blood-flow speed. Abstract--Better understanding

  2. Longitudinal, intermodality registration of quantitative breast PET and MRI data acquired before and during neoadjuvant chemotherapy: Preliminary results

    SciTech Connect (OSTI)

    Atuegwu, Nkiruka C.; Williams, Jason M. [Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2310 and Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2675 (United States)] [Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2310 and Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2675 (United States); Li, Xia; Arlinghaus, Lori R. [Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2310 (United States)] [Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2310 (United States); Abramson, Richard G. [Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2310 (United States) [Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2310 (United States); Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2675 (United States); Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232-6838 (United States); Chakravarthy, A. Bapsi [Department of Radiation Oncology, Vanderbilt University Medical Center, Nashville, Tennessee 37232-5671 and Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232-6838 (United States)] [Department of Radiation Oncology, Vanderbilt University Medical Center, Nashville, Tennessee 37232-5671 and Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232-6838 (United States); Abramson, Vandana G. [Department of Medical Oncology, Vanderbilt University Medical Center, Nashville, Tennessee 37232-6307 and Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232-6838 (United States)] [Department of Medical Oncology, Vanderbilt University Medical Center, Nashville, Tennessee 37232-6307 and Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232-6838 (United States); Yankeelov, Thomas E., E-mail: thomas.yankeelov@vanderbilt.edu [Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2310 (United States); Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2675 (United States); Department of Physics and Astronomy, Vanderbilt University, Nashville, Tennessee 37240-1807 (United States); Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee 37232-6838 (United States); Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee 37235-1631 (United States); Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232-6838 (United States)

    2014-05-15T23:59:59.000Z

    Purpose: The authors propose a method whereby serially acquired DCE-MRI, DW-MRI, and FDG-PET breast data sets can be spatially and temporally coregistered to enable the comparison of changes in parameter maps at the voxel level. Methods: First, the authors aligned the PET and MR images at each time point rigidly and nonrigidly. To register the MR images longitudinally, the authors extended a nonrigid registration algorithm by including a tumor volume-preserving constraint in the cost function. After the PET images were aligned to the MR images at each time point, the authors then used the transformation obtained from the longitudinal registration of the MRI volumes to register the PET images longitudinally. The authors tested this approach on ten breast cancer patients by calculating a modified Dice similarity of tumor size between the PET and MR images as well as the bending energy and changes in the tumor volume after the application of the registration algorithm. Results: The median of the modified Dice in the registered PET and DCE-MRI data was 0.92. For the longitudinal registration, the median tumor volume change was ?0.03% for the constrained algorithm, compared to ?32.16% for the unconstrained registration algorithms (p = 8 × 10{sup ?6}). The medians of the bending energy were 0.0092 and 0.0001 for the unconstrained and constrained algorithms, respectively (p = 2.84 × 10{sup ?7}). Conclusions: The results indicate that the proposed method can accurately spatially align DCE-MRI, DW-MRI, and FDG-PET breast images acquired at different time points during therapy while preventing the tumor from being substantially distorted or compressed.

  3. Research | NREL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclear Press ReleasesIn the Inorganic PV thrust,ResearchResearch

  4. MRI Predictive Factors for Tumor Response in Rectal Cancer Following Neoadjuvant Chemoradiation Therapy - Implications for Induction Chemotherapy?

    SciTech Connect (OSTI)

    Yu, Stanley K.T.; Tait, Diana [Radiotherapy Department, The Royal Marsden, Sutton/London (United Kingdom); Chau, Ian [Department of Medicine, The Royal Marsden, Sutton/London (United Kingdom); Brown, Gina, E-mail: gina.brown@rmh.nhs.uk [Academic Radiology Department, The Royal Marsden, Sutton/London (United Kingdom)

    2013-11-01T23:59:59.000Z

    Purpose: Clinical and magnetic resonance imaging (MRI) characteristics at baseline and following chemoradiation therapy (CRT) most strongly associated with histopathologic response were investigated and survival outcomes evaluated in accordance with imaging and pathological response. Methods and Materials: Responders were defined as mrT3c/d-4 downstaged to ypT0-2 on pathology or low at risk mrT2 downstaged to ypT1 or T0. Multivariate logistic regression of baseline and posttreatment MRI: T, N, extramural venous invasion (EMVI), circumferential resection margin, craniocaudal length <5 cm, and MRI tumor height ?5 cm were used to identify independent predictor(s) for response. An association between induction chemotherapy and EMVI status was analyzed. Survival outcomes for pathologic and MRI responders and nonresponders were analyzed. Results: Two hundred eighty-one patients were eligible; 114 (41%) patients were pathology responders. Baseline MRI negative EMVI (odds ratio 2.94, P=.007), tumor height ?5 cm (OR 1.96, P=.02), and mrEMVI status change (positive to negative) following CRT (OR 3.09, P<.001) were the only predictors for response. There was a strong association detected between induction chemotherapy and ymrEMVI status change after CRT (OR 9.0, P<.003). ymrT0-2 gave a positive predictive value of 80% and OR of 9.1 for ypT0-2. ymrN stage accuracy of ypN stage was 75%. Three-year disease-free survival for pathology and MRI responders were similar at 80% and 79% and significantly better than poor responders. Conclusions: Tumor height and mrEMVI status are more important than baseline size and stage of the tumor as predictors of response to CRT. Both MRI- and pathologic-defined responders have significantly improved survival. “Good response” to CRT in locally advanced rectal cancer with ypT0-2 carries significantly better 3-year overall survival and disease-free survival. Use of induction chemotherapy for improving mrEMVI status and knowledge of MRI predictive factors could be taken into account in the pursuit of individualized neoadjuvant treatments for patients with rectal cancer.

  5. Materials Research Institute 199 Materials Research Institute Building

    E-Print Network [OSTI]

    Lee, Dongwon

    to biotechnology, building materials to automobiles, and much more. With more than a century of expertise projects in Penn State history. MRI and the Huck Institutes for the Life Sciences will join together

  6. AR Researchers

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    for fixed-wing unmanned aerial vehicles with an emphasis in cooperative unmanned vehicle research and intelligent remote sensing. Cal Christensen, M.S., P.E., P.M.P Cal...

  7. Battlefield MRI

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    other scans for detecting changes in soft tissue, and early intervention for even mild brain injuries has been shown to significantly improve a patient's long-term prognosis....

  8. 1610 IEEE ANTENNAS AND WIRELESS PROPAGATION LETTERS, VOL. 11, 2012 MRI-Derived 3-D-Printed Breast Phantom

    E-Print Network [OSTI]

    Hagness, Susan C.

    1610 IEEE ANTENNAS AND WIRELESS PROPAGATION LETTERS, VOL. 11, 2012 MRI-Derived 3-D-Printed Breast--We propose a 3-D-printed breast phantom for use in preclinical experimental microwave imaging studies the proce- dure for generating the 3-D-printed breast phantom and present the measured dielectric properties

  9. Abstract --Recent human pharmacological fMRI studies suggest that oxytocin (OT) is a centrally-acting

    E-Print Network [OSTI]

    Dascalu, Sergiu

    Abstract -- Recent human pharmacological fMRI studies suggest that oxytocin (OT) is a centrally-acting neurotransmitter important in the development and expression of trusting relationships in men and women. OT of several key interacting brain regions affected by OT neurophysiology during social trust behavior

  10. Journal of Neuroscience Methods 169 (2008) 7683 Visual stimulus presentation using fiber optics in the MRI scanner

    E-Print Network [OSTI]

    Sereno, Martin

    2008-01-01T23:59:59.000Z

    Journal of Neuroscience Methods 169 (2008) 76­83 Visual stimulus presentation using fiber optics-face space using fiber optics in the MRI scanner. The feasibility of fiber-optic based displays-encoded paradigms in both experiments. The results suggest that fiber-optic based displays can be a complementary

  11. Artificial Neural Network Model for fMRI timeseries and a Framework for Comparison of Convolution Models

    E-Print Network [OSTI]

    Nielsen, Finn Årup

    Artificial Neural Network Model for fMRI timeseries and a Framework for Comparison of Convolution of the hemodynamic response was proposed in [5]. Here we propose an artificial neural network (ANN) model. Method The specific neural network we will use is a two­layer feed­forward type. Parameters are optimized

  12. Infarction of Uterine Fibroids After Embolization: Relationship Between Postprocedural Enhanced MRI Findings and Long-Term Clinical Outcomes

    SciTech Connect (OSTI)

    Katsumori, Tetsuya, E-mail: katsumo@eurus.dti.ne.jp; Kasahara, Toshiyuki; Kin, Yoko; Nozaki, Taiki [Saiseikai Shiga Hospital, Department of Radiology (Japan)

    2008-01-15T23:59:59.000Z

    Purpose. To retrospectively evaluate the relationship between the degree of infarction of uterine fibroids on enhanced MRI after embolization and long-term clinical outcomes. Methods. During 92 months, 290 consecutive patients with symptomatic uterine fibroids were treated with embolization; 221 who underwent enhanced MRI before embolization and 1 week after embolization were included in this study. The infarction rates of all fibroid tissue were assessed using enhanced MRI after embolization. Patients were divided into three groups according to the infarction rates: group A (100% infarction, n 142), group B (90-99% infarction, n = 74), group C (<90% infarction, n = 5). The cumulative rates of clinical outcomes were compared among groups using the Kaplan-Meier limited method. Results. Group A had a significantly higher rate of symptom control than groups B and C. The cumulative rates of symptom control at 5 years were 93%, 71%, and 60% in groups A, B, and C, respectively. Group A had a significantly lower rate of gynecologic intervention after embolization than groups B and C. The cumulative rates of additional gynecologic intervention at 5 years were 3%, 15%, and 20% in groups A, B, and C, respectively. Conclusions. The degree of infarction of uterine fibroids after embolization on enhanced MRI was related to long-term clinical outcomes. Complete infarction of all fibroid tissue can induce a higher rate of symptom control, with a lower rate of additional gynecologic intervention in the long term compared with incomplete infarction of fibroid tissue.

  13. Modeling fMRI data generated by overlapping cognitive processes with unknown onsets using Hidden Process Models

    E-Print Network [OSTI]

    Gordon, Geoffrey J.

    different numbers and types of underlying mental processes. We describe the HPM framework and its learning algorithm to train HPMs from fMRI data, and an inference algorithm that applies an HPM to infer the probable identities and start times of processes to explain additional observed data. The HPM learning algorithm

  14. The Mate Retention Inventory-Short Form (MRI-SF) David M. Buss a,*, Todd K. Shackelford b

    E-Print Network [OSTI]

    Pillow, Jonathan

    The Mate Retention Inventory-Short Form (MRI-SF) David M. Buss a,*, Todd K. Shackelford b , William . E-mail address: dbuss@psy.utexas.edu (D.M. Buss). www.elsevier.com/locate/paid Personality distinct domains--effort devoted to attracting a mate (Buss, 1988a; Buss & Schmitt, 1996) and effort

  15. Research Areas

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    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclear Press Releases 2014References by WebsitehomeResearch Areas

  16. Research Areas

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    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclear Press Releases 2014References by WebsitehomeResearch

  17. Research Highlight

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    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclear Press Releases 2014References byLaboratoryResearchRegime

  18. Research Help

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Scienceand Requirements Recently ApprovedReliabilityPrincipalResearch Finds VitaminResearch

  19. Research Highlight

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    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Scienceand Requirements Recently ApprovedReliabilityPrincipalResearch Finds VitaminResearchClouds,

  20. Research Highlight

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's PossibleRadiation Protection Technical s o Freiberge s 3 % A PB 2 7 7Research Form Research

  1. Research Highlight

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    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's PossibleRadiation Protection Technical s o Freiberge s 3 % A PB 2 7 7Research Form ResearchThe

  2. Collaboration | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of the largest research projects are as follows: The Midwest Center for Structural Genomics (MCSG), a component of the Protein Structure Initiative (PSI), is supported by a...

  3. Temporary Employment Opportunities | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Symposium Louis Stokes Midwest Center for Excellence Research Catalog Temporary Employment "My internship helped me to learn a great deal and make an informed decision as to...

  4. Location | JCESR

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    of Energy's Argonne National Laboratory, 25 miles southwest of Chicago at the heart of the Midwest's broad industrial and academic research and transportation...

  5. Healthcare Energy Efficiency Research and Development

    E-Print Network [OSTI]

    Lanzisera,, Judy Lai, Steven M.

    2012-01-01T23:59:59.000Z

    is one), and data center. Cooling Systems 6.2.1. Generalcooling systems for specialty needs in hospitals, like imagining (MRI’s), data centers

  6. Cyclotron Research Centre Universit de Lige

    E-Print Network [OSTI]

    Wolper, Pierre

    -clinic (animal): micro-PET, micro-CT, high-field 9.3T MR. · Human: PET, 3T MRI (functional, structural, diffusion

  7. Research | Energy Frontier Research Centers

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclear Press ReleasesIn the Inorganic PV thrust,Research Home Below

  8. SQUID-Detected MRI in the Limit of Zero Static Field

    SciTech Connect (OSTI)

    Kelso, Nathan Dean

    2009-12-14T23:59:59.000Z

    This thesis describes an implementation of the so-called"zero-field MRI" (ZFMRI) pulse sequence, which allows for imaging in an arbitrarily low B(0) field. The ZFMRI sequence created an effective unidirectional gradient field by using a train of pi pulses to average out the concomitant gradient components during encoding. The signals were acquired using a low-transition temperature dc Superconducting QUantum Interference Device (low-Tc dc SQUID) coupled to a first-order axial gradiometer. The experiments were carried out in a liquid helium dewar which was magnetically shielded with a single-layer mu-metal can around the outside and a superconducting Pb can contained within the helium space. We increased the filling factor of the custom-made, double-walled Pyrex insert by placing the liquid alcohol sample, at a temperature of approximately -50 degrees C, at the center of one loop of the superconducting gradiometer, which was immersed in the helium bath.

  9. Harmonic analysis for the characterization and correction of geometric distortion in MRI

    SciTech Connect (OSTI)

    Tadic, Tony, E-mail: ttadic@gmail.com; Stanescu, Teodor [Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto M5G 2M9, Canada and Department of Radiation Oncology, University of Toronto, Toronto M5S 3E2 (Canada); Jaffray, David A. [Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto M5G 2M9 (Canada); Department of Radiation Oncology, University of Toronto, Toronto M5S 3E2 (Canada); Department of Medical Biophysics, University of Toronto, Toronto M5G 1L7 (Canada)

    2014-11-01T23:59:59.000Z

    Purpose: Magnetic resonance imaging (MRI) is gaining widespread use in radiation therapy planning, patient setup verification, and real-time guidance of radiation delivery. Successful implementation of these technologies relies on the development of simple and efficient methods to characterize and monitor the geometric distortions arising due to system imperfections and gradient nonlinearities. To this end, the authors present the theory and validation of a novel harmonic approach to the quantification of system-related distortions in MRI. Methods: The theory of spatial encoding in MRI is applied to demonstrate that the 3D distortion vector field (DVF) is given by the solution of a second-order boundary value problem (BVP). This BVP is comprised of Laplace’s equation and a limited measurement of the distortion on the boundary of a specified region of interest (ROI). An analytical series expansion solving this BVP within a spherical ROI is obtained, and a statistical uncertainty analysis is performed to determine how random errors in the boundary measurements propagate to the ROI interior. This series expansion is then evaluated to obtain volumetric DVF mappings that are compared to reference data obtained on a 3 T full-body scanner. This validation is performed within two spheres of 20 cm diameter (one centered at the scanner origin and the other offset +3 cm along each of the transverse directions). Initially, a high-order mapping requiring measurements at 5810 boundary points is used. Then, after exploring the impact of the boundary sampling density and the effect of series truncation, a reduced-order mapping requiring measurements at 302 boundary points is evaluated. Results: The volumetric DVF mappings obtained from the harmonic analysis are in good agreement with the reference data. Following distortion correction using the high-order mapping, the authors estimate a reduction in the mean distortion magnitude from 0.86 to 0.42 mm and from 0.93 to 0.39 mm within the central and offset ROIs, respectively. In addition, the fraction of points with a distortion magnitude greater than 1 mm is reduced from 35.6% to 2.8% and from 40.4% to 1.5%, respectively. Similarly, following correction using the reduced-order mapping, the mean distortion magnitude reduces to 0.45–0.42 mm within the central and offset ROIs, and the fraction of points with a distortion magnitude greater than 1 mm is reduced to 2.8% and 1.5%, respectively. Conclusions: A novel harmonic approach to the characterization of system-related distortions in MRI is presented. This method permits a complete and accurate mapping of the DVF within a specified ROI using a limited measurement of the distortion on the ROI boundary. This technique eliminates the requirement to exhaustively sample the DVF at a dense 3D array of points, thereby permitting the design of simple, inexpensive phantoms that may incorporate additional modules for auxiliary quality assurance objectives.

  10. Temperature elevation by HIFU in ex vivo porcine muscle: MRI measurement and simulation study

    SciTech Connect (OSTI)

    Solovchuk, Maxim A., E-mail: solovchuk@gmail.com [Center for Advanced Study in Theoretical Sciences (CASTS), National Taiwan University, Taipei 10617, Taiwan (China); Hwang, San Chao; Chang, Hsu [Medical Engineering Research Division, National Health Research Institute, Miaoli 35053, Taiwan (China)] [Medical Engineering Research Division, National Health Research Institute, Miaoli 35053, Taiwan (China); Thiriet, Marc [Sorbonne Universités, UPMC Univ Paris 06, UMR 7598, Laboratoire Jacques-Louis Lions, F-75005, Paris (France)] [Sorbonne Universités, UPMC Univ Paris 06, UMR 7598, Laboratoire Jacques-Louis Lions, F-75005, Paris (France); Sheu, Tony W. H., E-mail: twhsheu@ntu.edu.tw [Department of Engineering Science and Ocean Engineering, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei 10617, Taiwan, Republic of China and Center for Advanced Study in Theoretical Sciences (CASTS), National Taiwan University, Taipei 10617, Taiwan (China)] [Department of Engineering Science and Ocean Engineering, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei 10617, Taiwan, Republic of China and Center for Advanced Study in Theoretical Sciences (CASTS), National Taiwan University, Taipei 10617, Taiwan (China)

    2014-05-15T23:59:59.000Z

    Purpose: High-intensity focused ultrasound is a rapidly developing medical technology with a large number of potential clinical applications. Computational model can play a pivotal role in the planning and optimization of the treatment based on the patient's image. Nonlinear propagation effects can significantly affect the temperature elevation and should be taken into account. In order to investigate the importance of nonlinear propagation effects, nonlinear Westervelt equation was solved. Weak nonlinear propagation effects were studied. The purpose of this study was to investigate the correlation between the predicted and measured temperature elevations and lesion in a porcine muscle. Methods: The investigated single-element transducer has a focal length of 12 cm, an aperture of 8 cm, and frequency of 1.08 MHz. Porcine muscle was heated for 30 s by focused ultrasound transducer with an acoustic power in the range of 24–56 W. The theoretical model consists of nonlinear Westervelt equation with relaxation effects being taken into account and Pennes bioheat equation. Results: Excellent agreement between the measured and simulated temperature rises was found. For peak temperatures above 85–90?°C “preboiling” or cavitation activity appears and lesion distortion starts, causing small discrepancy between the measured and simulated temperature rises. From the measurements and simulations, it was shown that distortion of the lesion was caused by the “preboiling” activity. Conclusions: The present study demonstrated that for peak temperatures below 85–90?°C numerical simulation results are in excellent agreement with the experimental data in three dimensions. Both temperature rise and lesion size can be well predicted. Due to nonlinear effect the temperature in the focal region can be increased compared with the linear case. The current magnetic resonance imaging (MRI) resolution is not sufficient. Due to the inevitable averaging the measured temperature can be 10–30?°C lower than the peak temperature. Computational fluid dynamics can provide additional important information that is lost using a state of the art MRI device.

  11. Research Highlight

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Scienceand Requirements Recently ApprovedReliabilityPrincipalResearch

  12. Research and Development with Full Scale Research

    E-Print Network [OSTI]

    Sijpheer, N.; Bakker, E.J.; Opstelten, I.

    2010-01-01T23:59:59.000Z

    One of the research programs of the Energy research Centre of the Netherlands (ECN) concerns the built environment. Several facilities to conduct the research activities are at ECN's disposal. One of these facilities, are five research dwellings...

  13. Summary of Research Instruction Research Instruction

    E-Print Network [OSTI]

    Kaji, Hajime

    for Passive corium cooling system under severe accident and reactor components (e.g. Fuel assembly, Steam Master's Program Doctoral Program Summary of Research Instruction Research Instruction Doctoral Program Summary of Research Instruction Research Instruction Application Code Name

  14. Global Health Research | 2 Global Health Research

    E-Print Network [OSTI]

    Rambaut, Andrew

    Global Health Research | 2 Global Health Research Supporting researchers in low- and middle-income countries to carry out health- related research within their own countries. Gl bal Health #12;3 | Global Health Research #12;Global Health Research | 4 We are a global charitable foundation dedicated

  15. “Calm Down Dear, It’s Only a Simulator.” An investigation into the effects of the fMRI environment on cognition. 

    E-Print Network [OSTI]

    Black, Ashley Anne

    2007-01-01T23:59:59.000Z

    Functional Magnetic Resonance Imaging (fMRI) is a useful tool which permits the observation of the brain’s neuronal activity in a non-invasive, on-line manner. The usefulness of the technique has however been questioned ...

  16. 445ISSN 1755-519110.2217/IIM.10.33 2010 Future Medicine Ltd Imaging Med. (2010) 2(4), 445457 MRI artifacts and correction strategies

    E-Print Network [OSTI]

    Southern California, University of

    2010-01-01T23:59:59.000Z

    . Perhaps most importantly, because it does not rely on ionizing radiation, MRI is safe for serial by a superconductive coil, one or more radiofrequency (RF) fields, and several weak magnetic fields generated by three

  17. Performance Analysis between Two Sparsity Constrained MRI Methods: Highly Constrained Backprojection(HYPR) and Compressed Sensing(CS) for Dynamic Imaging 

    E-Print Network [OSTI]

    Arzouni, Nibal

    2012-10-19T23:59:59.000Z

    One of the most important challenges in dynamic magnetic resonance imaging (MRI) is to achieve high spatial and temporal resolution when it is limited by system performance. It is desirable to acquire data fast enough to capture the dynamics...

  18. PNNL: Research

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    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclear Astrophysics OneOutreach EffortsSearch Welcome to

  19. Research Highlight

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    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclear Press Releases 2014References

  20. Research Highlight

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    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclear Press Releases 2014ReferencesStereo Photogrammetry Reveals

  1. Research Highlights

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    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclear Press Releases 2014ReferencesStereo Photogrammetry

  2. Research Library

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  4. Research Techniques

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  5. Research Tools

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  6. UNIRIB: Research

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  7. Research Gallery

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  8. Research Highlight

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  9. Research Highlight

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  10. Research Highlight

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  11. Research Highlight

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  12. Research Highlight

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  13. Research Highlight

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  14. Research Highlight

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  15. Research Highlight

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  17. Research Highlight

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  18. Research Highlight

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  20. Research Highlight

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  1. Research Highlight

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  2. Research Highlight

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  3. Research Highlight

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  4. Research Highlight

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  5. Research Highlight

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  6. Research Library

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

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  7. Research Projects

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  8. Research Facility,

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  9. Research Highlight

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  10. Research Highlight

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  11. Research Highlight

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  12. Research Highlight

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  13. Research Highlight

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  14. Research Highlight

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  15. Research Highlight

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  16. Research Highlight

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  17. Research Highlight

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  18. Research | Photosynthetic Antenna Research Center

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

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  19. NREL: Biomass Research - Research Staff

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Saleshttp://www.fnal.gov/directorate/nalcal/nalcal02_07_05_files/nalcal.gifNREL NRELChemical and CatalystNewResearch Staff Find

  20. SU-E-J-90: MRI-Based Treatment Simulation and Patient Setup for Radiation Therapy of Brain Cancer

    SciTech Connect (OSTI)

    Yang, Y [UCLA School of Medicine, Los Angeles, AA (United States); Cao, M; Han, F; Santhanam, A; Neylon, J; Gomez, C; Kaprealian, T; Sheng, K; Agazaryan, N; Low, D; Hu, P

    2014-06-01T23:59:59.000Z

    Purpose: Traditional radiation therapy of cancer is heavily dependent on CT. CT provides excellent depiction of the bones but lacks good soft tissue contrast, which makes contouring difficult. Often, MRIs are fused with CT to take advantage of its superior soft tissue contrast. Such an approach has drawbacks. It is desirable to perform treatment simulation entirely based on MRI. To achieve MR-based simulation for radiation therapy, bone imaging is an important challenge because of the low MR signal intensity from bone due to its ultra-short T2 and T1, which presents difficulty for both dose calculation and patient setup in terms of digitally reconstructed radiograph (DRR) generation. Current solutions will either require manual bone contouring or multiple MR scans. We present a technique to generate DRR using MRI with an Ultra Short Echo Time (UTE) sequence which is applicable to both OBI and ExacTrac 2D patient setup. Methods: Seven brain cancer patients were scanned at 1.5 Tesla using a radial UTE sequence. The sequence acquires two images at two different echo times. The two images were processed using in-house software. The resultant bone images were subsequently loaded into commercial systems to generate DRRs. Simulation and patient clinical on-board images were used to evaluate 2D patient setup with MRI-DRRs. Results: The majority bones are well visualized in all patients. The fused image of patient CT with the MR bone image demonstrates the accuracy of automatic bone identification using our technique. The generated DRR is of good quality. Accuracy of 2D patient setup by using MRI-DRR is comparable to CT-based 2D patient setup. Conclusion: This study shows the potential of DRR generation with single MR sequence. Further work will be needed on MR sequence development and post-processing procedure to achieve robust MR bone imaging for other human sites in addition to brain.

  1. SU-D-18C-06: Initial Experience with Implementing MRI Safety Guidelines for Patients with Pacemakers - Medical Physicist Perspective

    SciTech Connect (OSTI)

    James, J; Place, V; Panda, A [Mayo Clinic, Scottsdale, AZ (United States); Edmonson, H [Mayo Clinic College of Medicine, Rochester, MN (United States); Felmlee, J [Mayo Clinic, Rochester, MN (United States); Pooley, R [Mayo Clinic, Jacksonville, FL (United States)

    2014-06-01T23:59:59.000Z

    Purpose: Several institutions have developed MRI guidelines for patients with MR-unsafe or MR-conditional pacemakers. Here we highlight the role of a medical physicist in implementing these guidelines for non-pacemaker dependent patients. Guidelines: Implementing these guidelines requires involvement from several medical specialties and a strong collaboration with the site MRI supervisor to develop a structured workflow. A medical physicist is required to be present during the scan to supervise the MR scanning and to maintain a safety checklist that ensures: 1) uninterrupted patient communication with the technologist, 2) continuous patient physiologic monitoring (e.g. blood pressure and electrocardiography) by a trained nurse, 3) redundant patient vitals monitoring (e.g. pulse oximetry) due to the possibility of in vivo electrocardiography reading fluctuations during image acquisition. A radiologist is strongly recommended to be available to review the images before patients are discharged from the scanner. Pacemaker MRI should be restricted to 1.5T field strength. The MRI sequences should be optimized by the physicist with regards to: a) SAR: limited to <1.5 W/Kg for MR-unsafe pacemakers in normal operating mode, b) RF exposure time: <30 min, c) Coils: use T/R coils but not restricted to such, d) Artifacts: further optimization of sequences whenever image quality is compromised due to the pacemaker. In particular, cardiac, breast and left-shoulder MRIs are most susceptible to these artifacts. Possible strategies to lower the SAR include: a) BW reduction, 2) echo-train-length reduction, 3) increase TR, 4) decrease number of averages, 5) decrease flip angle, 6) reduce slices and/or a combination of all the options. Conclusion: A medical physicist in collaboration with the MR supervisor plays an important role in the supervision/implementation of safe MR scanning of pacemaker patients. Developing and establishing a workflow has enabled our institution to scan over 30 patients with pacemakers without complications, including 3 cardiac MR exams.

  2. Clinical Research Unit Translating research from

    E-Print Network [OSTI]

    Bandettini, Peter A.

    Clinical Research Unit Translating research from bench to bedside www.niehs.nih.gov/clinicalunit #12;National Institute of Environmental Health Sciences Clinical Research Program The National Institute of Environmental Health Sciences (NIEHS) Clinical Research Program and the Clinical Research Unit

  3. Detection of renal ischemic lesions using Gd-DTPA enhanced turbo FLASH MRI: Experimental and clinical results

    SciTech Connect (OSTI)

    Vosshenrich, R.; Fischer, U.; Funke, M.; Kopka, L.; Grabbe, E. [Univ. of Goettingen (Germany)] [and others] [Univ. of Goettingen (Germany); and others

    1996-03-01T23:59:59.000Z

    Our goal was to investigate the role of Gd-DTPA-enhanced dynamic MRI in the evaluation of renal ischemic lesions. With a turbo FLASH sequence before and after injection of Gd-DTPA, nine foxhound dogs after 60-120 min of renal ischemia underwent MR examination. In addition, five patients with a tumor in a solitary kidney were examined before and after nephron-sparing renal surgery to evaluate renal perfusion and function. The experimental and clinical findings were correlated with conventional measurements of kidney function and with histological findings. Complete renal ischemia leads to a poor corticomedullary differentiation in Gd-DTPA-enhanced turbo FLASH MRI. The signal-intensity-versus-time plots of kidneys with significant postischemic changes show a less steep increase of signal intensity in the cortex and a steeper increase of signal intensity in the medulla than those of normal kidneys. Dynamic MRI demonstrate renal morphology and reflect the functional status of the renal vasculature. 21 refs., 8 figs., 1 tab.

  4. MRI-based treatment planning with pseudo CT generated through atlas registration

    SciTech Connect (OSTI)

    Uh, Jinsoo, E-mail: jinsoo.uh@stjude.org; Merchant, Thomas E.; Hua, Chiaho [Department of Radiological Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee 38105 (United States)] [Department of Radiological Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee 38105 (United States); Li, Yimei; Li, Xingyu [Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105 (United States)] [Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105 (United States)

    2014-05-15T23:59:59.000Z

    Purpose: To evaluate the feasibility and accuracy of magnetic resonance imaging (MRI)-based treatment planning using pseudo CTs generated through atlas registration. Methods: A pseudo CT, providing electron density information for dose calculation, was generated by deforming atlas CT images previously acquired on other patients. The authors tested 4 schemes of synthesizing a pseudo CT from single or multiple deformed atlas images: use of a single arbitrarily selected atlas, arithmetic mean process using 6 atlases, and pattern recognition with Gaussian process (PRGP) using 6 or 12 atlases. The required deformation for atlas CT images was derived from a nonlinear registration of conjugated atlas MR images to that of the patient of interest. The contrasts of atlas MR images were adjusted by histogram matching to reduce the effect of different sets of acquisition parameters. For comparison, the authors also tested a simple scheme assigning the Hounsfield unit of water to the entire patient volume. All pseudo CT generating schemes were applied to 14 patients with common pediatric brain tumors. The image similarity of real patient-specific CT and pseudo CTs constructed by different schemes was compared. Differences in computation times were also calculated. The real CT in the treatment planning system was replaced with the pseudo CT, and the dose distribution was recalculated to determine the difference. Results: The atlas approach generally performed better than assigning a bulk CT number to the entire patient volume. Comparing atlas-based schemes, those using multiple atlases outperformed the single atlas scheme. For multiple atlas schemes, the pseudo CTs were similar to the real CTs (correlation coefficient, 0.787–0.819). The calculated dose distribution was in close agreement with the original dose. Nearly the entire patient volume (98.3%–98.7%) satisfied the criteria of chi-evaluation (<2% maximum dose and 2 mm range). The dose to 95% of the volume and the percentage of volume receiving at least 95% of the prescription dose in the planning target volume differed from the original values by less than 2% of the prescription dose (root-mean-square, RMS < 1%). The PRGP scheme did not perform better than the arithmetic mean process with the same number of atlases. Increasing the number of atlases from 6 to 12 often resulted in improvements, but statistical significance was not always found. Conclusions: MRI-based treatment planning with pseudo CTs generated through atlas registration is feasible for pediatric brain tumor patients. The doses calculated from pseudo CTs agreed well with those from real CTs, showing dosimetric accuracy within 2% for the PTV when multiple atlases were used. The arithmetic mean process may be a reasonable choice over PRGP for the synthesis scheme considering performance and computational costs.

  5. Research and Development with Full Scale Research 

    E-Print Network [OSTI]

    Sijpheer, N.; Bakker, E.J.; Opstelten, I.

    2010-01-01T23:59:59.000Z

    One of the research programs of the Energy research Centre of the Netherlands (ECN) concerns the built environment. Several facilities to conduct the research activities are at ECN's disposal. One of these facilities, are ...

  6. Use of 3.0-T MRI for Stereotactic Radiosurgery Planning for Treatment of Brain Metastases: A Single-Institution Retrospective Review

    SciTech Connect (OSTI)

    Saconn, Paul A.; Shaw, Edward G.; Chan, Michael D.; Squire, Sarah E. [Department of Radiation Oncology, Wake Forest University School of Medicine, Winston-Salem, North Carolina (United States); Johnson, Annette J. [Department of Radiology, Wake Forest University School of Medicine, Winston-Salem, North Carolina (United States); McMullen, Kevin P. [Department of Radiation Oncology, Wake Forest University School of Medicine, Winston-Salem, North Carolina (United States); Tatter, Stephen B.; Ellis, Thomas L. [Department of Neurosurgery, Wake Forest University School of Medicine, Winston-Salem, North Carolina (United States); Lovato, James [Department of Biostatistics, Wake Forest University School of Medicine, Winston-Salem, North Carolina (United States); Bourland, J. Daniel; Ekstrand, Kenneth E.; DeGuzman, Allan F. [Department of Radiation Oncology, Wake Forest University School of Medicine, Winston-Salem, North Carolina (United States); Munley, Michael T., E-mail: mmunley@wfubmc.ed [Department of Radiation Oncology, Wake Forest University School of Medicine, Winston-Salem, North Carolina (United States)

    2010-11-15T23:59:59.000Z

    Purpose: To investigate the efficacy of 3.0-T magnetic resonance imaging (MRI) for detecting brain metastases for stereotactic radiosurgery (SRS) planning. Methods and Materials: All adult patients scheduled for SRS treatment for brain metastases at our institution between October 2005 and January 2008 were eligible for analysis. All patients underwent radiosurgery treatment planning 3.0-T MRI on the day of scheduled radiosurgery and a diagnostic 1.5-T MRI in the days or weeks prior to radiosurgery for comparison. Both scans were interpreted by neuroradiologists who reported their findings in the radiology reports. We performed a retrospective review of the radiology reports to determine the number of brain metastases identified using each MRI system. Results: Of 254 patients scheduled for treatment from October 2005 to January 2008, 138 patients had radiology reports that explicitly described the number of metastases identified on both scans. With a median interval of 17 days (range, 1-82) between scans, the number of metastases detected using 1.5-T MRI system ranged from 1 to 5 and from 1 to 8 using the 3.0 T-MRI system. Twenty-two percent of patients were found to have a greater number of metastases with the 3.0 T-MRI system. The difference in number of metastases detected between the two scans for the entire cohort ranged from 0 to 6. Neither histology (p = 0.52 by chi-sq test) nor time between scans (p = 0.62 by linear regression) were significantly associated with the difference in number of metastases between scans. Conclusions: The 3.0-T MRI system appears to be superior to a 1.5-T MRI system for detecting brain metastases, which may have significant implications in determining the appropriate treatment modality. Our findings suggest the need for a prospectively designed study to further evaluate the use of a 3.0 T-MRI system for stereotactic radiosurgery planning in the treatment of brain metastases.

  7. Research Frontiers Cutting-Edge Research

    E-Print Network [OSTI]

    Takada, Shoji

    Research Frontiers Cutting-Edge Research in Kyoto University Kyoto University is known. Some of them exhibit circularly polarized light (CPL) with unprecedented anisotropy factors: they emit

  8. TransForumNews from Argonne's Transportation Research Program www.transportation.anl.gov

    E-Print Network [OSTI]

    Kemner, Ken

    page 10 A revolutionary advance in our understanding of how diesel engines work may unlock new at the local and regional level. 16 How Might Increased Biofuel Production Affect Midwest Water Supplies Laboratory recently won a three-year, $3.44 million grant from the U.S. Department of Energy's Advanced

  9. 84 Topics, Problems, and Questions Suggested for Faculty-Supervised Undergraduate or Graduate Research Projects

    E-Print Network [OSTI]

    Rose, Michael R.

    energy producers as far away as the Midwest (typically, wind farm consortia) while carbon system that meets California air quality standards and is acceptable to the campus community? Note acceptance of on-site incineration or "conversion technology" (by whatever name). 2. An in-depth study

  10. Research Documentation Guidelines Capturing knowledge, improving research

    E-Print Network [OSTI]

    Sommerville, Ian

    researchers. The RAISER development process is an SDLC specific to Software Engineering by Computer Science

  11. Information Brief on Green Power Marketing

    E-Print Network [OSTI]

    -3393 NREL is a U.S. Department of Energy Laboratory Operated by Midwest Research Institute ···· Battelle Golden, Colorado 80401-3393 NREL is a U.S. Department of Energy Laboratory Operated by Midwest Research Swezey and Lori Bird National Renewable Energy Laboratory 1617 Cole Boulevard Golden, Colorado 80401

  12. September 2004 NREL/TP-620-36833 Trends in Utility Green Pricing

    E-Print Network [OSTI]

    Energy by Midwest Research Institute · Battelle Contract No. DE-AC36-99-GO10337 #12;September 2004 · NREL Efficiency and Renewable Energy by Midwest Research Institute · Battelle Contract No. DE-AC36-99-GO10337 #12 and Karen Cardinal National Renewable Energy Laboratory 1617 Cole Boulevard, Golden, Colorado 80401-3393 303

  13. PVWATTS Version 2 Enhanced Spatial Resolution

    E-Print Network [OSTI]

    of Energy Laboratory Operated by Midwest Research Institute ···· Battelle ···· Bechtel Contract No. DE-AC36 Renewable Energy Laboratory 1617 Cole Boulevard Golden, Colorado 80401-3393 NREL is a U.S. Department-99-GO10337 #12;NOTICE The submitted manuscript has been offered by an employee of the Midwest Research

  14. A national laboratory of the U.S. Department of Energy Office of Energy Efficiency & Renewable Energy

    E-Print Network [OSTI]

    by Midwest Research Institute Battelle Contract No. DE-AC36-99-GO10337 #12;Renewable Energy Price Energy by Midwest Research Institute · Battelle Contract No. DE-AC36-99-GO10337 #12;NOTICE This reportA national laboratory of the U.S. Department of Energy Office of Energy Efficiency & Renewable

  15. A national laboratory of the U.S. Department of Energy Office of Energy Efficiency & Renewable Energy

    E-Print Network [OSTI]

    by Midwest Research Institute Battelle Contract No. DE-AC36-99-GO10337 #12;National Renewable Energy.S. Department of Energy Office of Energy Efficiency and Renewable Energy by Midwest Research InstituteA national laboratory of the U.S. Department of Energy Office of Energy Efficiency & Renewable

  16. September 1998 ! NREL/SR-580-25145 Methane Recovery from

    E-Print Network [OSTI]

    Laughlin, Robert B.

    Managed by Midwest Research Institute for the U.S. Department of Energy under contract No. DE-AC36-83CH.S. Department of Energy Managed by Midwest Research Institute for the U.S. Department of Energy under contract Casebook P. Lusk Resource Development Associates Washington, DC National Renewable Energy Laboratory 1617

  17. Magnetization curves of sintered heavy tungsten alloys for applications in MRI-guided radiotherapy

    SciTech Connect (OSTI)

    Kolling, Stefan [Sydney Medical School, University of Sydney, NSW 2006 (Australia)] [Sydney Medical School, University of Sydney, NSW 2006 (Australia); Oborn, Bradley M. [Illawarra Cancer Care Centre (ICCC), Wollongong, NSW 2500, Australia and Centre for Medical Radiation Physics (CMRP), University of Wollongong, Wollongong, NSW 2500 (Australia)] [Illawarra Cancer Care Centre (ICCC), Wollongong, NSW 2500, Australia and Centre for Medical Radiation Physics (CMRP), University of Wollongong, Wollongong, NSW 2500 (Australia); Keall, Paul J., E-mail: paul.keall@sydney.edu.au [Sydney Medical School, University of Sydney, NSW 2006, Australia and Ingham Institute for Applied Medical Research, Liverpool, NSW 2170 (Australia); Horvat, Joseph [Institute for Superconducting and Electronic Materials, University of Wollongong, Wollongong, NSW 2500, Australia and School of Physics, University of Wollongong, Wollongong, NSW 2500 (Australia)] [Institute for Superconducting and Electronic Materials, University of Wollongong, Wollongong, NSW 2500, Australia and School of Physics, University of Wollongong, Wollongong, NSW 2500 (Australia)

    2014-06-15T23:59:59.000Z

    Purpose: Due to the current interest in MRI-guided radiotherapy, the magnetic properties of the materials commonly used in radiotherapy are becoming increasingly important. In this paper, measurement results for the magnetization (BH) curves of a range of sintered heavy tungsten alloys used in radiation shielding and collimation are presented. Methods: Sintered heavy tungsten alloys typically contain >90?% tungsten and <10?% of a combination of iron, nickel, and copper binders. Samples of eight different grades of sintered heavy tungsten alloys with varying binder content were investigated. Using a superconducting quantum interference detector magnetometer, the induced magnetic momentm was measured for each sample as a function of applied external field H{sub 0} and the BH curve derived. Results: The iron content of the alloys was found to play a dominant role, directly influencing the magnetizationM and thus the nonlinearity of the BH curve. Generally, the saturation magnetization increased with increasing iron content of the alloy. Furthermore, no measurable magnetization was found for all alloys without iron content, despite containing up to 6% of nickel. For two samples from different manufacturers but with identical quoted nominal elemental composition (95% W, 3.5% Ni, 1.5% Fe), a relative difference in the magnetization of 11%–16% was measured. Conclusions: The measured curves show that the magnetic properties of sintered heavy tungsten alloys strongly depend on the iron content, whereas the addition of nickel in the absence of iron led to no measurable effect. Since a difference in the BH curves for two samples with identical quoted nominal composition from different manufacturers was observed, measuring of the BH curve for each individual batch of heavy tungsten alloys is advisable whenever accurate knowledge of the magnetic properties is crucial. The obtained BH curves can be used in FEM simulations to predict the magnetic impact of sintered heavy tungsten alloys.

  18. Nanomaterials driven energy, environmental and biomedical research

    SciTech Connect (OSTI)

    Sharma, Prakash C.; Srinivasan, Sesha S.; Wilson, Jeremiah F. [Department of Physics, College of Arts and Sciences, Tuskegee University, Tuskegee, AL 36088 (United States)

    2014-03-31T23:59:59.000Z

    We have developed state-of-the-art nanomaterials such as nanofibers, nanotubes, nanoparticles, nanocatalysts and nanostructures for clean energy, environmental and biomedical research. Energy can neither be created nor be destroyed, but it can be converted from one form to another. Based on this principle, chemical energy such as hydrogen has been produced from water electrolysis at a much lower voltage using RuO{sub 2} nanoparticles on the Si wafer substrate. Once the hydrogen is produced from the clean sources such as solar energy and water, it has to be stored by physisorption or chemisorption processes on to the solid state systems. For the successful physical adsorption of hydrogen molecule, we have developed novel polyaniline nanostructures via chemical templating and electrospinning routes. Chemical or complex hydrides involving nano MgH{sub 2} and transition metal nanocatalysts have been synthesized to tailor both the thermodynamics and kinetics of hydrogen (chemi) sorption respectively. Utilization of solar energy (UV-Vis) and a coupling of novel semiconductor oxide nanoparticles have been recently demonstrated with enhancement in photo-oxidation and/or photo-reduction processes for the water/air detoxification and sustainable liquid fuel production respectively. Magnetic nanoparticles such as ZnFe{sub 2}O{sub 4} have been synthesized and optimized for biomedical applications such as targeted drug delivery and tumor diagnostic sensing (MRI)

  19. Geographic Visualization of the 1993 Midwest Flood Water Balance

    E-Print Network [OSTI]

    White, W. Scott; Ridd, Merrill K.; Mizgalewicz, Pawel J.; Maidment, David R.

    2003-01-01T23:59:59.000Z

    , flooding, and water storage. By the middle of July, large amounts of water were being stored in the southern part of the UMRB, particularly around the St. Louis area where the Mississippi and Missouri Rivers meet. Water was also being stored in larger...) includes the Mississippi River basin from the river’s headwaters in Minnesota to Cairo, Illinois, and the Lower Missouri River basin below Gavins Point dam, South Dakota, to St. Louis, Missouri (Figure 1.1). Using a digital elevation model of the study...

  20. Midwest Jewish Studies Association Conference York University, Toronto, Canda

    E-Print Network [OSTI]

    Cavusoglu, Cenk

    and IB 1A: Crypto-Jewish Identity, Real and Imagined Chair: Peter Haas, Case Western Reserve University" Judith Neulander, Case Western Reserve University "Music and Identity in Iberian Jewish and Crypto) "Patriot Games: Ottoman Jews, Transnational Ties, and Divided Loyalties during the Balkan Wars and World

  1. Midwest Consortium for Wind Turbine Reliability and Optimization

    SciTech Connect (OSTI)

    Scott R. Dana; Douglas E. Adams; Noah J. Myrent

    2012-05-11T23:59:59.000Z

    This report provides an overview of the efforts aimed to establish a student focused laboratory apparatus that will enhance Purdue's ability to recruit and train students in topics related to the dynamics, operations and economics of wind turbines. The project also aims to facilitate outreach to students at Purdue and in grades K-12 in the State of Indiana by sharing wind turbine operational data. For this project, a portable wind turbine test apparatus was developed and fabricated utilizing an AirX 400W wind energy converter. This turbine and test apparatus was outfitted with an array of sensors used to monitor wind speed, turbine rotor speed, power output and the tower structural dynamics. A major portion of this project included the development of a data logging program used to display real-time sensor data and the recording and creation of output files for data post-processing. The apparatus was tested in an open field to subject the turbine to typical operating conditions and the data acquisition system was adjusted to obtain desired functionality to facilitate use for student projects in existing courses offered at Purdue University and Indiana University. Data collected using the data logging program is analyzed and presented to demonstrate the usefulness of the test apparatus related to wind turbine dynamics and operations.

  2. 72nd Midwest PDE Seminar | Fall 2013 | Purdue University

    E-Print Network [OSTI]

    Charles Smart, MIT Shu-Ming Sun, Virginia Tech Vladimir Sverak, University of Minnesota Konstantina Trivisa, University of Maryland Shankar Venakataramani

  3. Midwest Motor Systems Consortium- A Unique Business Partnership

    E-Print Network [OSTI]

    Hackner, R.; Cockrill, C.

    be more efficient because the needs of all the parties are considered from the start. A collaborative process avoids solutions that will have to be redesigned later because previously un known factors were not considered. Sweden has used collaborative... processes to solve problems in the construction industry. One example is the retrofitting of elevators in older buildings. Sweden, like the U.S., has a wowing population of older people. Many of them live on upper floors of older apartment buildings...

  4. CHP in the Midwest - Presentation from the July 2010 Advancing...

    Broader source: Energy.gov (indexed) [DOE]

    improving manufacturing competitiveness and standard of living. recycledenergymidwestCHP More Documents & Publications QER - Comment of International District Energy...

  5. Coordination of Retail Demand Response with Midwest ISO Markets

    E-Print Network [OSTI]

    Bharvirkar, Ranjit

    2008-01-01T23:59:59.000Z

    MISO MP MRO MWDRI M&V NYISO PJM PUC RAP RFC RTO RTP SERC AirRTOs such as New England or PJM. In 2005 MISO became theEdison is a member of PJM). Interruptible (Total = 3398, N =

  6. Coordination of Retail Demand Response with Midwest ISO Markets

    E-Print Network [OSTI]

    Bharvirkar, Ranjit

    2008-01-01T23:59:59.000Z

    MISO, 2006) 2: MISO Reliability "Footprint" (Source: ICF,for power. Figure 2: MISO Reliability "Footprint" (Source:resources as part of the MISO reliability planning process.

  7. Midwest Appropriate Technology Small Grants Program: management analysis

    SciTech Connect (OSTI)

    Not Available

    1983-10-01T23:59:59.000Z

    This report reviews 84 projects conducted with DOE funding. The projects cover a number of energy-related topics, including biomass conversion, solar energy, wind energy, energy education, energy conservation, and recycling. In an effort to assist DOE-Chicago in analyzing what types of grantees were more successful and why, the projects were ranked and grouped by several variables. To determine if particular characteristics functioned to make one project more successful than another, several statistical tests were conducted. While the results of quantitative testing are somewhat offset by the subjective nature of the project rankings, some patterns did seem to develop: The overall distribution of the projects showed a normal division: 23% superior, 55% average, and 23% poor. No particular grantee type was significantly more successful than the others, but colleges and universities did have fewer highly ranked projects than any other group. Michigan had proportionately more superior projects; Illinois and Ohio proportionately fewer. Grant awards over $40,000 yielded fewer superior projects.

  8. Sustainable bioenergy production from marginal lands in the US Midwest

    SciTech Connect (OSTI)

    Gelfand, Ilya; Sahajpal, Ritvik; Zhang, Xuesong; Izaurralde, Roberto C.; Gross, Katherine L.; Robertson, G. P.

    2013-01-24T23:59:59.000Z

    Long-term measurements of global warming impact coupled with spatially explicit modeling suggests that both climate benefits and the production potential of cellulosic crops grown on marginal lands of the US North Central region are substantial but will be insufficient to meet long-term biofuel needs.

  9. EERE Leadership Discusses Energy Innovation in Midwest | Department of

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742Energy China U.S.ContaminationJulySavannah RiverSustainability |Innovations inP agov

  10. Tribal Rights, Sovereignty, and Economic Development in the Midwest

    Office of Energy Efficiency and Renewable Energy (EERE)

    Throughout Indian Country, there are significant legal issues impacting Tribal rights and sovereignty. As most of you are aware, Indian Country squeaked out a win for tribal sovereignty in the...

  11. DOE Recognizes Midwest Industrial Efficiency Leaders | Department of Energy

    Office of Environmental Management (EM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742 33 111 1,613PortsmouthBartlesvilleAbout »Department of2 DOEDepartment| DepartmentRailcarDOE

  12. Midwest Renewable Energy Corporation Partners LLC | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directedAnnual Siteof Energy 2,AUDIT REPORTEnergyFarmsPower CoLongxingPartners LLC Place: Florida Zip: FL

  13. Midwest Renewable Energy Projects LLC | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are being directedAnnual Siteof Energy 2,AUDIT REPORTEnergyFarmsPower CoLongxingPartners LLC Place: Florida Zip:

  14. Midwest (PADD 2) Total Crude Oil and Products Imports

    U.S. Energy Information Administration (EIA) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov YouKizildere IRaghuraji Agro IndustriesTownDells,1Stocks Nov-14 Dec-14 Jan-15LiquidBG 0 20 40 60 8079,

  15. Upper Midwest Hydrogen Initiative UMHI | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are beingZealand Jump to:Ezfeedflag JumpID-fTri Global Energy LLCEnergy) Redirect page JumpCorpUniversityLPUpland,UMHI

  16. Midwest (PADD 2) Total Crude Oil and Products Imports

    Gasoline and Diesel Fuel Update (EIA)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for On-Highway4,1,50022,3,,,,6,1,9,1,50022,3,,,,6,1,Decade1 Source: Office of Fossil Energy, U.S. Department of28Fuel Ethanol

  17. Midwest Regional Carbon Sequestration Partnership-Validation Phase

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOEThe Bonneville PowerCherries 82981-1cnHighandSWPA / SPRA / USACE625Data ShowC -9MicrowaveFuel Ethanol

  18. DOE Recognizes Midwest Industrial Efficiency Leaders | Department of Energy

    Office of Environmental Management (EM)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742 33 1112011AT&T,Office of Policy, OAPM |TRU WasteAdministrator |20.1CPlanEP9425 701

  19. EA-343 Midwest Independent Transmission Operator (MISO) | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't Your Destiny:Revised Finding of No53197EFindingEA-257-CEA-296-B22

  20. Hawkeye Renewables formerly Midwest Renewables | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov You are8COaBulkTransmissionSitingProcess.pdfGetec AG|Information OpenEIHas Been Happening Jump to:Hawaiian

  1. Midwest (PADD 2) Gasoline and Diesel Retail Prices

    U.S. Energy Information Administration (EIA) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov YouKizildere IRaghuraji Agro IndustriesTownDells, Wisconsin:DeploymentSite Name:24,High824 2.839 2.835 2.826OE-417,0

  2. EA-343 Midwest Independent Transmission Operator (MISO) | Department of

    Broader source: Energy.gov (indexed) [DOE]

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742Energy China 2015 Business42.1Energy |Final Site-WideBPAPowerEE US No.SubsidaryShellEnergy

  3. Midwest City, Oklahoma: Energy Resources | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov YouKizildere I Geothermal Pwer Plant JumpMarysville, Ohio:Menomonee| OpenMickeyDelaware: EnergyMidnight

  4. Midwest Ethanol Producers Inc MEPI | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov YouKizildere I Geothermal Pwer Plant JumpMarysville, Ohio:Menomonee| OpenMickeyDelaware: EnergyMidnightProducers Inc MEPI

  5. Midwest Renewable Energy Services LLC | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov YouKizildere I Geothermal Pwer Plant JumpMarysville, Ohio:Menomonee| OpenMickeyDelaware: EnergyMidnightProducersLLC

  6. Midwest Region Alternative Fuels Project | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't YourTransport(FactDepartment3311,Official FileEnergy Midsize Wind Turbines forDepartment of2

  7. Midwest Region Alternative Fuels Project | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't YourTransport(FactDepartment3311,Official FileEnergy Midsize Wind Turbines forDepartment

  8. Midwest Region Alternative Fuels Project | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't YourTransport(FactDepartment3311,Official FileEnergy Midsize Wind Turbines forDepartment0

  9. Midwest/Mountain Alternative Fuel Initiative | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page on Google Bookmark EERE: Alternative Fuels DataDepartment of Energy Your Density Isn't YourTransport(FactDepartment3311,Official FileEnergy Midsize Wind Turbines

  10. The Midwest Energy Efficiency Alliance | Open Energy Information

    Open Energy Info (EERE)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative Fuels Data Center Home Page onYou are now leaving Energy.gov You are now leaving Energy.gov YouKizildere IRaghuraji Agro Industries PvtStratosolarTharaldson Ethanol LLC Jump to:Uncertainty of1801 - 1891(d)) |

  11. Forensic Science Education Programs in the Midwest | The Ames Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Science (SC) Environmental Assessments (EA)Budget(DANCE) Target 1Annual Waste Forecast

  12. Gradient Echo MRI Characterization of Development of Atherosclerosis in the Abdominal Aorta in Watanabe Heritable Hyperlipidemic Rabbits

    SciTech Connect (OSTI)

    Wang, Yi-Xiang J., E-mail: yi-xiang.wang@astrazeneca.com; Kuribayashi, Hideto [AstraZeneca (United Kingdom); Wagberg, Maria [AstraZeneca (Sweden); Holmes, Andrew P.; Tessier, Jean J.; Waterton, John C. [AstraZeneca (United Kingdom)

    2006-08-15T23:59:59.000Z

    Purpose. The Watanabe Heritable Hyperlipidemic (WHHL) rabbit provides an important model of spontaneous atherosclerosis. With a strain of WHHL rabbits which do not develop abdominal aorta lumen stenosis even with advanced atherosclerosis, we studied the MRI-histology correlation, and the natural progression of atherosclerosis in the abdominal aorta. In addition, intra-reader segmentation repeatability and scan-rescan reproducibility were assessed. Methods. Two batches of female WHHL rabbits were used. The first batch of 6 rabbits was scanned at 20 weeks old. A second batch of 17 rabbits was scanned at 50 weeks old and then randomly divided into two subgroups: 8 were killed for histologic investigation; 9 were kept alive for follow-up, with repeat scanning a week later to assess scan-rescan reproducibility, and again at 73 weeks old to assess disease progression. MR images were acquired at 4.7 T using a chemical shift selective fat suppression gradient echo with a saturation band suppressing blood signal within the aortic lumen. Five slices per animal were acquired, centered around the renal artery region of the abdominal aorta, with in-plane resolution of 0.195 mm and slice thickness of 3 mm. Results. The coefficient of variation for intra-reader reproducibility for aortic wall thickness measurements was 2.5% for repeat segmentations of the same scans on the same day, but segmentations of these same scans made 8 months later showed a systematic change, suggesting that intra-reader bias as well as increased variability could compromise assessments made over time. Comparative analyses were therefore performed in one postprocessing session. The coefficient of variation for scan-rescan reproducibility for aortic wall thickness was 5.5% for nine pairs of scans acquired a week apart and segmented on the same day. Good MRI-histology correlation was obtained. The MRI-measured mean aortic wall thickness of animals at 20 weeks of age was 76% that of animals at 50 weeks of age (p < 0.001). There was a small increase in aortic wall thickness between 50 and 73 weeks of age, but this was not significant (p > 0.05). The corresponding differences in lumen cross-sectional areas at 20, 50, and 73 weeks of age were not significant. These results were consistent with in-house historical histology data on this strain of rabbits. Conclusions. High-resolution gradient echo MRI can follow disease progression in the WHHL rabbit spontaneous atherosclerosis disease model.

  13. Summary of the Midwest conference on small-scale hydropower in the Midwest: an old technology whose time has come

    SciTech Connect (OSTI)

    None

    1980-05-01T23:59:59.000Z

    A variety of decision makers convened to examine and discuss certain significant problems associated with small-scale hydroelectric development in the Midwestern region, comprised of Illinois, Indiana, Kentucky, Michigan, Ohio, West Virginia, and Wisconsin. The conference opened with an introductory panel of resource persons who outlined the objectives of the conference, presented information on small-scale hydro, and described the materials available to conference participants. A series of workshop sessions followed. Two of the workshop sessions discussed problems and policy responses raised by state and Federal regulation. The remaining two workshops dealt with economic issues confronting small-scale hydro development and the operation and usefulness of the systems dynamics model developed by the Thayer School of Engineering at Dartmouth College. A plenary session and recommendations completed the workshop.

  14. Research Councils UK Transforming

    E-Print Network [OSTI]

    Berzins, M.

    Research Councils UK Transforming our energy future #12;Research funded by the Research Councils in 2002 to create a viable renewable energy research community to foster industrial engagement of research, expertise and the business capability to develop and exploit them commercially. Energy and its

  15. External Research Funding Agreements

    E-Print Network [OSTI]

    Victoria, University of

    1 External Research Funding Agreements University Policy No: RH8200 Classification: Research and university employees under Research Funding Agreements. DEFINITIONS 2.00 Research Funding Agreement means funding provided through an agreement with the university to be used for research purposes, whether

  16. Forest Research: Climate Change

    E-Print Network [OSTI]

    Forest Research: Climate Change projects Forest Research is part of the Forestry Commission of climate change-related research is wide-ranging, covering impact assessment and monitoring, adaptation around a quarter of its research budget with Forest Research on climate change and related programmes

  17. RESEARCH INFRASTRUCTURES Roadmap 2008

    E-Print Network [OSTI]

    Horn, David

    RESEARCH INFRASTRUCTURES FOR FRANCE Roadmap 2008 #12;INTRODUCTION European research infrastructures and development, benefiting to Europe's economy and competitiveness. This roadmap for the research infrastructures....................................................................................................6 3. The roadmap: existing and already decided RIs and others at the planning stage

  18. INTERNATIONAL PACIFIC RESEARCH CENTER

    E-Print Network [OSTI]

    Wang, Yuqing

    INTERNATIONAL PACIFIC RESEARCH CENTER APRIL 2004­MARCH 2005 REPORT SCHOOL OF OCEAN AND EARTH RESEARCH HIGHLIGHTS Indo-Pacific Ocean Climate Pacific Research Center Design by: Susan Yamamoto Printed by: Hagadone Printing Company Photo: Waikiki

  19. Universiteit Antwerpen Research Methods

    E-Print Network [OSTI]

    Nierstrasz, Oscar

    Methods Science vs. Engineering 5 Science Engineering Physics Chemistry Biology Mathematics ElectroUniversiteit Antwerpen Research Methods in Computer Science (Serge Demeyer -- University of Antwerp Introduction · Origins of Computer Science · Research Philosophy Research Methods · Feasibility study · Pilot

  20. Applying for Research Awards

    E-Print Network [OSTI]

    ... 53.22 KB APPLYING FOR RESEARCH AWARDS The Eastern Bird Banding Association seeks applicants for its annual $500 research awards in aid of research using banding techniques or bird banding data. ...

  1. Sandia Hydrogen Combustion Research

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Hydrogen Combustion Research Sandia Hydrogen Combustion Research Sebastian A. Kaiser (PI) Sandia National Laboratories Christopher M. White University of New Hampshire Sponsor: DoE...

  2. Nuclear Physics: Experiment Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    UserResearcher Information print version Research Highlights Public Interest Nuclear Physics Accelerator Free Electron Laser (FEL) Medical Imaging Physics Topics Campaigns...

  3. Operations Research Analyst

    Broader source: Energy.gov [DOE]

    The incumbent in this position will serve as an Operations Research Analyst in the Generation Scheduling (PGS). The Operations Research Analyst is responsible for analytical work that involves...

  4. National Renewable Energy Laboratory Innovation for Our Energy Future

    E-Print Network [OSTI]

    of the U.S. Department of Energy Office of Energy Efficiency & Renewable Energy NREL is operated by Midwest Efficiency and Renewable Energy by Midwest Research Institute · Battelle Contract No. DE-AC36-99-GO10337 #12National Renewable Energy Laboratory Innovation for Our Energy Future A national laboratory

  5. September 2004 NREL/TP-620-36823 Green Power Marketing in the

    E-Print Network [OSTI]

    of Energy Efficiency and Renewable Energy by Midwest Research Institute · Battelle Contract No. DE-AC36.nrel.gov Operated for the U.S. Department of Energy Office of Energy Efficiency and Renewable Energy by Midwest Seventh Edition Lori Bird and Blair Swezey National Renewable Energy Laboratory 1617 Cole Boulevard

  6. Green Power Marketing in the United States: A Status Report

    E-Print Network [OSTI]

    80401-3393 NREL is a U.S. Department of Energy Laboratory Operated by Midwest Research Institute Boulevard Golden, Colorado 80401-3393 NREL is a U.S. Department of Energy Laboratory Operated by Midwest-28738 Blair Swezey and Lori Bird National Renewable Energy Laboratory 1617 Cole Boulevard Golden, Colorado

  7. Green Power Marketing in the United States: A Status Report

    E-Print Network [OSTI]

    , Colorado 80401-3393 NREL is a U.S. Department of Energy Laboratory Operated by Midwest Research Institute Boulevard Golden, Colorado 80401-3393 NREL is a U.S. Department of Energy Laboratory Operated by Midwest/TP-620-35119 Lori Bird and Blair Swezey National Renewable Energy Laboratory 1617 Cole Boulevard Golden

  8. NOVEL CONCEPTS RESEARCH IN GEOLOGIC STORAGE OF CO2 PHASE III THE OHIO RIVER VALLEY CO2 STORAGE PROJECT

    SciTech Connect (OSTI)

    Neeraj Gupta

    2005-05-26T23:59:59.000Z

    As part of the Department of Energy's (DOE) initiation on developing new technologies for storage of carbon dioxide in geologic reservoir, Battelle has been awarded a project to investigate the feasibility of CO{sub 2} sequestration in the deep saline reservoirs in the Ohio River Valley region. This project is the Phase III of Battelle's work under the Novel Concepts in Greenhouse Gas Management grant. The main objective of the project is to demonstrate that CO{sub 2} sequestration in deep formations is feasible from engineering and economic perspectives, as well as being an inherently safe practice and one that will be acceptable to the public. In addition, the project is designed to evaluate the geology of deep formations in the Ohio River Valley region in general and in the vicinity of AEP's Mountaineer Power Plant in particular, in order to determine their potential use for conducting a long-term test of CO{sub 2} disposal in deep saline formations and potentially in nearby deep coal seams. The current technical progress report summarizes activities completed for the January through March 2005 period of the project. As discussed in the report, the technical activities focused on development of injection well design, preparing a Class V Underground Injection Control permit, assessment of monitoring technologies, analysis of coal samples for testing the capture system by Mitsubishi Heavy Industry, and presentation of project progress at several venues. In addition, related work has progressed on a collaborative risk assessment project with Japan research institute CREIPI and technical application for the Midwest Regional Carbon Sequestration Partnership.

  9. Eddy currents in a transverse MRI gradient coil. J.M.B. Kroot, S.J.L. van Eijndhoven, A.A.F. van de Ven

    E-Print Network [OSTI]

    Eindhoven, Technische Universiteit

    Eddy currents in a transverse MRI gradient coil. J.M.B. Kroot, S.J.L. van Eijndhoven, A.A.F. van de logarithmically singular kernel represents inductive effects related to the occurrence of eddy currents on the development of eddy currents in the gradient coils, which have a negative effect on the uniformity

  10. A wavelet-based estimator of the degrees of freedom in denoised fMRI time series for probabilistic testing of functional connectivity and brain graphs

    E-Print Network [OSTI]

    Patel, Ameera X.; Bullmore, Edward T.

    2015-05-03T23:59:59.000Z

    by denoising algorithms for head movement. Here, we used a wavelet-based method both to denoise fMRI data and to estimate the (effective) df of the denoised process. We show that seed voxel correlations corrected for locally variable df could be tested...

  11. ANTENNAS AND WIRELESS PROPAGATION LETTERS, VOL. X, NO. X, JANUARY 2013 1 MRI-derived 3D-printed breast phantom for

    E-Print Network [OSTI]

    Van Veen, Barry D.

    ANTENNAS AND WIRELESS PROPAGATION LETTERS, VOL. X, NO. X, JANUARY 2013 1 MRI-derived 3D-printed--We propose a 3D-printed breast phantom for use in pre-clinical experimental microwave imaging studies the procedure for generating the 3D-printed breast phantom and present the measured dielectric properties

  12. Figure 1: The MRI robot controller system we developed a modular control system including a set of 4-ch low noise, high-power, waveform synthesizers that

    E-Print Network [OSTI]

    Camesano, Terri

    the accuracy limits of traditional mechanical templates (5mm resolution), 2) robots can be designed for interventional procedures. We have developed a modular MRI robot controller (Fig. 1) designed for operating all. The robot, shown in Fig. 2 (right), provides for three axes of Cartesian positioning (2-DOF lateral

  13. Int. J. Patt. Recog. Art. Intell., Special Issue on MR Brain Image Analysis, 1997 1 An Integrated Approach for Locating Neuroanatomical Structure from MRI1

    E-Print Network [OSTI]

    Duncan, James S.

    Int. J. Patt. Recog. Art. Intell., Special Issue on MR Brain Image Analysis, 1997 1 An Integrated Approach for Locating Neuroanatomical Structure from MRI1 Lawrence H. Staib , Amit Chakrabortyy and James S results on synthetic and MR brain images show a significant improvement is achieved as a consequence

  14. Int. J. Patt. Recog. Art. Intell., Special Issue on MR Brain Image Analysis, 1997 1 An Integrated Approach for Locating Neuroanatomical Structure from MRI 1

    E-Print Network [OSTI]

    Int. J. Patt. Recog. Art. Intell., Special Issue on MR Brain Image Analysis, 1997 1 An Integrated Approach for Locating Neuroanatomical Structure from MRI 1 Lawrence H. Staib \\Lambda , Amit Chakraborty y gradient­ based surface finder. Experimental results on synthetic and MR brain images show a significant

  15. Real-time prediction of the reversibility of the ultrasound-induced blood-brain barrier opening using passive cavitation detection with MRI validation

    E-Print Network [OSTI]

    Konofagou, Elisa E.

    using passive cavitation detection with MRI validation Tao Sun1 , Gesthimani Samiotaki1 and Elisa E, represented by the cavitation dose, as monitored during BBB opening to the reversibility of BBB opening). A single-element, pulse-echo ultrasound transducer served as a passive cavitation detector was used

  16. Research at Research Development Services and

    E-Print Network [OSTI]

    · $400M ongoing upgrade · FEL Light Source (~14kW) CEBAF #12;Alternative Energy ·Algal Biodiesel Research

  17. Sandia National Laboratories: Research: Research Foundations...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Radiation Effects and High Energy Density Science Rings of Saturn, Sandia's workhorse pulsed-power machine. The Radiation Effects and High Energy Density Science Research...

  18. Postdoctoral Research Awards Annual Research Meeting: Jun Lu...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Jun Lu Postdoctoral Research Awards Annual Research Meeting: Jun Lu Poster Presentation at 2012 EERE Annual Research Meeting, Postdoctoral Research Awards, from the U.S. Department...

  19. Postdoctoral Research Awards Annual Research Meeting: Jared Clark...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Jared Clark Postdoctoral Research Awards Annual Research Meeting: Jared Clark Poster Presentation at the 2012 EERE Annual Research Meeting, Postdoctoral Research Awards, from the...

  20. Postdoctoral Research Awards Annual Research Meeting: Sarah Hobdey...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Sarah Hobdey Postdoctoral Research Awards Annual Research Meeting: Sarah Hobdey Poster Presentation at 2012 EERE Annual Research Meeting, Postdoctoral Research Awards, from the...

  1. Postdoctoral Research Awards Annual Research Meeting: Neil Dasgupta...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Neil Dasgupta Postdoctoral Research Awards Annual Research Meeting: Neil Dasgupta Poster Presentation at 2012 EERE Annual Research Meeting, Postdoctoral Research Awards, from the...

  2. Postdoctoral Research Awards Annual Research Meeting: David Lampert...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    David Lampert Postdoctoral Research Awards Annual Research Meeting: David Lampert Poster Presentation at 2012 EERE Annual Research Meeting, Postdoctoral Research Awards, from the...

  3. Postdoctoral Research Awards Annual Research Meeting: Brian Larsen...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Brian Larsen Postdoctoral Research Awards Annual Research Meeting: Brian Larsen Poster Presentation at 2012 EERE Annual Research Meeting, Postdoctoral Research Awards, from the...

  4. Animal Testing Medical Research

    E-Print Network [OSTI]

    Bech, Claus

    Arondsen Marit Gystøl #12;ZO-8091 Forsøksdyrlære Animal experiments in medical research NTNU ­ Norges ..................................................................................................................................................... 14 #12;ZO-8091 Forsøksdyrlære Animal experiments in medical research NTNU ­ Norges Teknisk have come from animal research. Animal research is defined as the use of non-human animals

  5. Jahresbericht der Research Academy

    E-Print Network [OSTI]

    Schüler, Axel

    Jahresbericht der Research Academy Leipzig 2008 #12;Inhalt Die Research Academy Leipzig 3 Vorwort Research Academy Leipzig im Aufwind 3 Die Arbeit der RAL-Doktorandenvertretung 2008 4 Fächerübergreifendes Qualifikationsprogramm Die Veranstaltungen der Research Academy Leipzig 2008 5 Seminar ,,Junge Wissenschaft und Praxis" 6

  6. Microsoft External Research Backgrounder

    E-Print Network [OSTI]

    Narasayya, Vivek

    are undeniable. M icrosoft Research believes that collaboration between the public and private sectors, combined with the power of computing, can help researchers as they work to solve the most urgent challenges in medicine, Building the Future of Technology Microsoft External Research Backgrounder #12;The team promotes research

  7. Mapping motion from 4D-MRI to 3D-CT for use in 4D dose calculations: A technical feasibility study

    SciTech Connect (OSTI)

    Boye, Dirk [Center for Proton Therapy, Paul Scherrer Institut, 5232 Villigen-PSI (Switzerland); Computer Vision Laboratory, ETH Zuerich, 8092 Zuerich (Switzerland); Lomax, Tony [Center for Proton Therapy, Paul Scherrer Institut, 5232 Villigen-PSI (Switzerland); ETH Zuerich, 8092 Zuerich (Switzerland); Knopf, Antje [Center for Proton Therapy, Paul Scherrer Institut, 5232 Villigen-PSI (Switzerland)

    2013-06-15T23:59:59.000Z

    Purpose: Target sites affected by organ motion require a time resolved (4D) dose calculation. Typical 4D dose calculations use 4D-CT as a basis. Unfortunately, 4D-CT images have the disadvantage of being a 'snap-shot' of the motion during acquisition and of assuming regularity of breathing. In addition, 4D-CT acquisitions involve a substantial additional dose burden to the patient making many, repeated 4D-CT acquisitions undesirable. Here the authors test the feasibility of an alternative approach to generate patient specific 4D-CT data sets. Methods: In this approach motion information is extracted from 4D-MRI. Simulated 4D-CT data sets [which the authors call 4D-CT(MRI)] are created by warping extracted deformation fields to a static 3D-CT data set. The employment of 4D-MRI sequences for this has the advantage that no assumptions on breathing regularity are made, irregularities in breathing can be studied and, if necessary, many repeat imaging studies (and consequently simulated 4D-CT data sets) can be performed on patients and/or volunteers. The accuracy of 4D-CT(MRI)s has been validated by 4D proton dose calculations. Our 4D dose algorithm takes into account displacements as well as deformations on the originating 4D-CT/4D-CT(MRI) by calculating the dose of each pencil beam based on an individual time stamp of when that pencil beam is applied. According to corresponding displacement and density-variation-maps the position and the water equivalent range of the dose grid points is adjusted at each time instance. Results: 4D dose distributions, using 4D-CT(MRI) data sets as input were compared to results based on a reference conventional 4D-CT data set capturing similar motion characteristics. Almost identical 4D dose distributions could be achieved, even though scanned proton beams are very sensitive to small differences in the patient geometry. In addition, 4D dose calculations have been performed on the same patient, but using 4D-CT(MRI) data sets based on variable breathing patterns to show the effect of possible irregular breathing on active scanned proton therapy. Using a 4D-CT(MRI), including motion irregularities, resulted in significantly different proton dose distributions. Conclusions: The authors have demonstrated that motion information from 4D-MRI can be used to generate realistic 4D-CT data sets on the basis of a single static 3D-CT data set. 4D-CT(MRI) presents a novel approach to test the robustness of treatment plans in the circumstance of patient motion.

  8. U.S, Department of Energy's Bioenergy Research Centers An Overview of the Science

    SciTech Connect (OSTI)

    None

    2009-07-01T23:59:59.000Z

    Alternative fuels from renewable cellulosic biomass--plant stalks, trunks, stems, and leaves--are expected to significantly reduce U.S. dependence on imported oil while enhancing national energy security and decreasing the environmental impacts of energy use. Ethanol and other advanced biofuels from cellulosic biomass are renewable alternatives that could increase domestic production of transportation fuels, revitalize rural economies, and reduce carbon dioxide and pollutant emissions. According to U.S. Secretary of Energy Steven Chu, 'Developing the next generation of biofuels is key to our effort to end our dependence on foreign oil and address the climate crisis while creating millions of new jobs that can't be outsourced'. In the United States, the Energy Independence and Security Act (EISA) of 2007 is an important driver for the sustainable development of renewable biofuels. As part of EISA, the Renewable Fuel Standard mandates that 36 billion gallons of biofuels are to be produced annually by 2022, of which 16 billion gallons are expected to come from cellulosic feedstocks. Although cellulosic ethanol production has been demonstrated on a pilot level, developing a cost-effective, commercial-scale cellulosic biofuel industry will require transformational science to significantly streamline current production processes. Woodchips, grasses, cornstalks, and other cellulosic biomass are widely abundant but more difficult to break down into sugars than corn grain--the primary source of U.S. ethanol fuel production today. Biological research is key to accelerating the deconstruction of cellulosic biomass into sugars that can be converted to biofuels. The Department of Energy (DOE) Office of Science continues to play a major role in inspiring, supporting, and guiding the biotechnology revolution over the past 25 years. The DOE Genomic Science Program is advancing a new generation of research focused on achieving whole-systems understanding for biology. This program is bringing together scientists in diverse fields to understand the complex biology underlying solutions to DOE missions in energy production, environmental remediation, and climate change science. New interdisciplinary research communities are emerging, as are knowledgebases and scientific and computational resources critical to advancing large-scale, genome-based biology. To focus the most advanced biotechnology-based resources on the biological challenges of biofuel production, DOE established three Bioenergy Research Centers (BRCs) in September 2007. Each center is pursuing the basic research underlying a range of high-risk, high-return biological solutions for bioenergy applications. Advances resulting from the BRCs will provide the knowledge needed to develop new biobased products, methods, and tools that the emerging biofuel industry can use. The scientific rationale for these centers and for other fundamental genomic research critical to the biofuel industry was established at a DOE workshop involving members of the research community (see sidebar, Biofuel Research Plan, below). The DOE BRCs have developed automated, high-throughput analysis pipelines that will accelerate scientific discovery for biology-based biofuel research. The three centers, which were selected through a scientific peer-review process, are based in geographically diverse locations--the Southeast, the Midwest, and the West Coast--with partners across the nation. DOE's Oak Ridge National Laboratory leads the BioEnergy Science Center (BESC) in Tennessee; the University of Wisconsin-Madison leads the Great Lakes Bioenergy Research Center (GLBRC); and DOE's Lawrence Berkeley National Laboratory leads the DOE Joint BioEnergy Institute (JBEI) in California. Each center represents a multidisciplinary partnership with expertise spanning the physical and biological sciences, including genomics, microbial and plant biology, analytical chemistry, computational biology and bioinformatics, and engineering. Institutional partners include DOE national laboratories, universities, private companies,

  9. Research Roadmap Presentation

    E-Print Network [OSTI]

    Sloman, Aaron

    Research Roadmap Presentation: euCognition Meeting, Munich 12 Jan 2007 http://www.eucognition.org/six_monthly_meeting_2.htm What's a Research Roadmap For? Why do we need one? How can we produce one? Aaron Sloman ( http.cs.bham.ac.uk/research/projects/cosy/papers/#pr0701 See also the euCognition Research Roadmap project: http://www.eucognition.org/wiki/index.php?title=Research_Roadmap

  10. Non-invasive, MRI-compatible fibreoptic device for functional near-IR reflectometry of human brain

    SciTech Connect (OSTI)

    Sorvoja, H.S.S.; Myllylae, T S; Myllylae, Risto A [University of Oulu, Optoelectronics and Measurements Techniques Laboratory (Finland); Kirillin, M Yu; Sergeeva, Ekaterina A [Institute of Applied Physics, Russian Academy of Sciences, Nizhnii Novgorod (Russian Federation); Elseoud, A A; Nikkinen, J; Tervonen, O; Kiviniemi, V [MRI Research Unit, Department of Diagnostic Radiology, Oulu University Hospital, Oulu (Finland)

    2011-01-24T23:59:59.000Z

    A non-invasive device for measuring blood oxygen variations in human brain is designed, implemented, and tested for MRI compatibility. The device is based on principles of near-IR reflectometry; power LEDs serve as sources of probing radiation delivered to patient skin surface through optical fibres. Numerical Monte Carlo simulations of probing radiation propagation in a multilayer brain model are performed to evaluate signal levels at different source - detector separations at three operation wavelengths and an additional wavelength of 915 nm. It is shown that the device can be applied for brain activity studies using power LEDs operating at 830 and 915 nm, while employment of wavelength of 660 nm requires an increased probing power. Employment of the wavelength of 592 nm in the current configuration is unreasonable. (application of lasers and laser-optical methods in life sciences)

  11. Computational Modeling of an MRI Guided Drug Delivery System Based on Magnetic Nanoparticle Aggregations for the Navigation of Paramagnetic Nanocapsules

    E-Print Network [OSTI]

    N. K. Lampropoulos; E. G. Karvelas; I. E. Sarris

    2015-04-14T23:59:59.000Z

    A computational method for magnetically guided drug delivery is presented and the results are compared for the aggregation process of magnetic particles within a fluid environment. The model is developed for the simulation of the aggregation patterns of magnetic nanoparticles under the influence of MRI magnetic coils. A novel approach for the calculation of the drag coefficient of aggregates is presented. The comparison against experimental and numerical results from the literature is showed that the proposed method predicts well the aggregations in respect to their size and pattern dependance, on the concentration and the strength of the magnetic field, as well as their velocity when particles are driven through the fluid by magnetic gradients.

  12. Disruption of the neural response to rapid acoustic stimuli in dyslexia: Evidence from functional MRI

    E-Print Network [OSTI]

    Poldrack, Russ

    Disruption of the neural response to rapid acoustic stimuli in dyslexia: Evidence from functional. M. Merzenich, September 27, 2000 The biological basis for developmental dyslexia remains unknown. Research has suggested that a fundamental deficit in dyslexia is the inability to process sensory input

  13. The need for clinical quantification of combined PET/MRI data in pediatric epilepsy

    E-Print Network [OSTI]

    Hua, Jing

    decade PET/CT showed the added value of multi- modality integration for both research and clinical oncology. In fact, since 2000, the world market share of PET/CT scanners increased from less than 5 by combined PET and CT imaging has improved both the localization and staging of tumors in addition

  14. Semiautomatic segmentation and follow-up of multicomponent low-grade tumors in longitudinal brain MRI studies

    SciTech Connect (OSTI)

    Weizman, Lior, E-mail: weizmanl@gmail.com [School of Engineering and Computer Science, The Hebrew University of Jerusalem, Jerusalem 91904 (Israel)] [School of Engineering and Computer Science, The Hebrew University of Jerusalem, Jerusalem 91904 (Israel); Sira, Liat Ben [Department of Radiology, Tel Aviv Medical Center, Tel Aviv University, Tel Aviv 64239 (Israel)] [Department of Radiology, Tel Aviv Medical Center, Tel Aviv University, Tel Aviv 64239 (Israel); Joskowicz, Leo [School of Engineering and Computer Science and The Edmond and Lily Safra Center for Brain Sciences (ELSC), The Hebrew University of Jerusalem, Jerusalem 91904 (Israel)] [School of Engineering and Computer Science and The Edmond and Lily Safra Center for Brain Sciences (ELSC), The Hebrew University of Jerusalem, Jerusalem 91904 (Israel); Rubin, Daniel L.; Yeom, Kristen W. [Department of Radiology, Stanford University, Stanford, California 94305 (United States)] [Department of Radiology, Stanford University, Stanford, California 94305 (United States); Constantini, Shlomi; Shofty, Ben [Tel Aviv Medical Center, Dana Children's Hospital, Tel Aviv University, Tel Aviv 64239 (Israel)] [Tel Aviv Medical Center, Dana Children's Hospital, Tel Aviv University, Tel Aviv 64239 (Israel); Bashat, Dafna Ben [Tel Aviv Medical Center, Functional Brain Center, Tel Aviv University, Tel Aviv 64239 (Israel)] [Tel Aviv Medical Center, Functional Brain Center, Tel Aviv University, Tel Aviv 64239 (Israel)

    2014-05-15T23:59:59.000Z

    Purpose: Tracking the progression of low grade tumors (LGTs) is a challenging task, due to their slow growth rate and associated complex internal tumor components, such as heterogeneous enhancement, hemorrhage, and cysts. In this paper, the authors show a semiautomatic method to reliably track the volume of LGTs and the evolution of their internal components in longitudinal MRI scans. Methods: The authors' method utilizes a spatiotemporal evolution modeling of the tumor and its internal components. Tumor components gray level parameters are estimated from the follow-up scan itself, obviating temporal normalization of gray levels. The tumor delineation procedure effectively incorporates internal classification of the baseline scan in the time-series as prior data to segment and classify a series of follow-up scans. The authors applied their method to 40 MRI scans of ten patients, acquired at two different institutions. Two types of LGTs were included: Optic pathway gliomas and thalamic astrocytomas. For each scan, a “gold standard” was obtained manually by experienced radiologists. The method is evaluated versus the gold standard with three measures: gross total volume error, total surface distance, and reliability of tracking tumor components evolution. Results: Compared to the gold standard the authors' method exhibits a mean Dice similarity volumetric measure of 86.58% and a mean surface distance error of 0.25 mm. In terms of its reliability in tracking the evolution of the internal components, the method exhibits strong positive correlation with the gold standard. Conclusions: The authors' method provides accurate and repeatable delineation of the tumor and its internal components, which is essential for therapy assessment of LGTs. Reliable tracking of internal tumor components over time is novel and potentially will be useful to streamline and improve follow-up of brain tumors, with indolent growth and behavior.

  15. Research Teams - Combustion Energy Frontier Research Center

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645U.S. DOE Office of Scienceand Requirements RecentlyElectronic Public Reading Room ElectronicResearchResearchResearch

  16. Senior Research Associate Taconite Industry Minerals Research Endowed Chair

    E-Print Network [OSTI]

    Netoff, Theoden

    Senior Research Associate Taconite Industry Minerals Research Endowed Chair Job Requisition 170892 Coleraine Minerals Research Laboratory Natural Resources Research Institute University of Minnesota Duluth (www.nrri.umn.edu) Position Description The Taconite Industry Minerals Research Endowed Chair

  17. 2009 Wind Technologies Market Report

    E-Print Network [OSTI]

    Wiser, Ryan

    2010-01-01T23:59:59.000Z

    Offered Rate Midwest Independent System Operator MMS MNDOCInterconnection, Midwest Independent System Operator (MISO),2009. Midwest Independent Transmission System Operator, Inc.

  18. Gasification Research BIOENERGY PROGRAM

    E-Print Network [OSTI]

    Gasification Research BIOENERGY PROGRAM Description Researchers inthe@tamu.edu Skid-mounted gasifier: 1.8 tons-per-day pilot unit Gasification of cotton gin trash The new Texas A

  19. Photocatalysis Currently, the research

    E-Print Network [OSTI]

    Vollmer, Heribert

    Photocatalysis Currently, the research activit in the area ofies Photocatalysis focus on the topics Photocatalysis and Prof. Dr. Detlef Bahnemann Nanotechnology Research Topics Bioprocess Engineering Bioprocess Modeling and Control Photocatalysis and Nanotechnology Institute of Technical Chemistry Contact Person

  20. University Research Summaries

    Broader source: Energy.gov [DOE]

    The Idaho National Laboratory published the U.S. Department of Energy's (DOE) Geothermal Technologies Office 2001 University Research Summaries. 

  1. Xu Zhang's Homepage - Research

    E-Print Network [OSTI]

    Research Interests. Numerical Methods for Partial Differential Equations; Finite Element and Discontinuous Galerkin Methods; Immersed Finite Element Methods

  2. Graduate Research Scholarships

    E-Print Network [OSTI]

    and Engineering Research Council of Canada Master's scholarships (17,5K, one year, non- renewable) Doctoral Research of Canada Master's scholarships (17,5K for one year, non- renewable) Doctoral scholarships (30k scholarships (20K per year, first nine semesters) Social Sciences and Humanities Research Council of Canada

  3. RESEARCH BUILDING AT NORTHWESTERN

    E-Print Network [OSTI]

    Engman, David M.

    BIOMEDICAL RESEARCH BUILDING AT NORTHWESTERN MEDICINE #12;"Our new Biomedical Research Building-intensive medical schools. Perkins+Will has designed a building that will be superbly functional and have great a magnificent 12-story Biomedical Research Building to address this priority. The new 600,000 square foot

  4. INTERNATIONAL PACIFIC RESEARCH CENTER

    E-Print Network [OSTI]

    Wang, Yuqing

    INTERNATIONAL PACIFIC RESEARCH CENTER Annual Report April 2006 ­ March 2007 School of Ocean Research Center 1 2 The Year's Highlights 3 Research Accomplishments Indo-Pacific Ocean Climate 4 Regional-Ocean Ocean Climate: To understand climate variations in the Pacific and Indian oceans on inter- annual

  5. Natural Sciences Research Outlook

    E-Print Network [OSTI]

    Sciences (July 2009), including: UK Research Councils: Biotechnology and Biological· Sciences ResearchEpARTmENT oF phySICS 14 CENTRE FoR ENVIRoNmENTAL poLICy 15 RESEARCh INSTITUTES ANd CENTRES 16 ENERGy ANd ENVIRo

  6. Researchers Edition 2014

    E-Print Network [OSTI]

    Genève, Université de

    on the thematic priorities "Translational biomedical research and medical techno- logy" and "Renewable Energy of Geneva (UNIGE). UNIGE's researchers annually obtain more than 130 million Swiss Francs, earmarked for research, from sources such as: the Swiss National Science Foundation (SNSF), the European Union (EU

  7. BRAZIL RESEARCH INITIATIVES

    E-Print Network [OSTI]

    Liu, Taosheng

    BRAZIL RESEARCH INITIATIVES Michigan State University (MSU) identifies Brazil as a global priority and challenges become increasingly part of the U.S.-Brazil agenda, MSU desires partnerships aimed at producing in the U.S. and one in Brazil, to share research strategies and explore joint projects in several research

  8. Reservoir Characterization Research Laboratory

    E-Print Network [OSTI]

    Texas at Austin, University of

    Reservoir Characterization Research Laboratory for Carbonate Studies Executive Summary for 2014 Outcrop and Subsurface Characterization of Carbonate Reservoirs for Improved Recovery of Remaining/Al 0.00 0.02 0.04 Eagle Ford Fm #12;#12; Reservoir Characterization Research Laboratory Research Plans

  9. Louisiana Transportation Research Center

    E-Print Network [OSTI]

    Harms, Kyle E.

    Louisiana Transportation Research Center LTRC www.ltrc.lsu.edu 2012-13 ANNUALREPORT #12;The Louisiana Transportation Research Center (LTRC) is a research, technology transfer, and training center administered jointly by the Louisiana Department of Transportation and Development (DOTD) and Louisiana State

  10. HR Strategy for Researchers

    E-Print Network [OSTI]

    Fabra, established in 1990, is a research-oriented, public higher education institution. UPF has of international researchers that it recruits. Consistent with this commitment to internationalization, UPF signed of Researchers (hereafter, the Charter and Code) in 2010. UPF belongs to the 3rd Cohort of the Human Resources

  11. Research Councils UK Engaging Young

    E-Print Network [OSTI]

    Rambaut, Andrew

    Research Councils UK Engaging Young People with Cutting Edge Research: a guide for researchers to the feel-good factor researchers can have a hand in inspiring the next generation of researchers, to secure

  12. The Cost of Transmission for Wind Energy: A Review of Transmission Planning Studies

    E-Print Network [OSTI]

    Mills, Andrew D.

    2009-01-01T23:59:59.000Z

    2007. “Inclusion of Wind in the MISO Transmission Expansionhttp://www.jcspstudy.org/ Midwest ISO (MISO). 2007. Midwest+Planning Midwest ISO (MISO). 2003. Midwest Transmission

  13. U.S. Department of Energy's Bioenergy Research Centers An Overview of the Science

    SciTech Connect (OSTI)

    None

    2010-07-01T23:59:59.000Z

    Alternative fuels from renewable cellulosic biomass - plant stalks, trunks, stems, and leaves - are expected to significantly reduce U.S. dependence on imported oil while enhancing national energy security and decreasing the environmental impacts of energy use. Ethanol and other advanced biofuels from cellulosic biomass are renewable alternatives that could increase domestic production of transportation fuels, revitalize rural economies, and reduce carbon dioxide and pollutant emissions. According to U.S. Secretary of Energy Steven Chu, 'Developing the next generation of biofuels is key to our effort to end our dependence on foreign oil and address the climate crisis while creating millions of new jobs that can't be outsourced.' Although cellulosic ethanol production has been demonstrated on a pilot level, developing a cost-effective, commercial-scale cellulosic biofuel industry will require transformational science to significantly streamline current production processes. Woodchips, grasses, cornstalks, and other cellulosic biomass are widely abundant but more difficult to break down into sugars than corn grain - the primary source of U.S. ethanol fuel production today. Biological research is key to accelerating the deconstruction of cellulosic biomass into sugars that can be converted to biofuels. The Department of Energy (DOE) Office of Science continues to play a major role in inspiring, supporting, and guiding the biotechnology revolution over the past 30 years. The DOE Genomic Science program is advancing a new generation of research focused on achieving whole-systems understanding of biology. This program is bringing together scientists in diverse fields to understand the complex biology underlying solutions to DOE missions in energy production, environmental remediation, and climate change science. For more information on the Genomic Science program, see p. 26. To focus the most advanced biotechnology-based resources on the biological challenges of biofuel production, DOE established three Bioenergy Research Centers (BRCs) in September 2007. Each center is pursuing the basic research underlying a range of high-risk, high-return biological solutions for bioenergy applications. Advances resulting from the BRCs are providing the knowledge needed to develop new biobased products, methods, and tools that the emerging biofuel industry can use (see sidebar, Bridging the Gap from Fundamental Biology to Industrial Innovation for Bioenergy, p. 6). The DOE BRCs have developed automated, high-throughput analysis pipelines that will accelerate scientific discovery for biology-based biofuel research. The three centers, which were selected through a scientific peer-review process, are based in geographically diverse locations - the Southeast, the Midwest, and the West Coast - with partners across the nation (see U.S. map, DOE Bioenergy Research Centers and Partners, on back cover). DOE's Lawrence Berkeley National Laboratory leads the DOE Joint BioEnergy Institute (JBEI) in California; DOE's Oak Ridge National Laboratory leads the BioEnergy Science Center (BESC) in Tennessee; and the University of Wisconsin-Madison leads the Great Lakes Bioenergy Research Center (GLBRC). Each center represents a multidisciplinary partnership with expertise spanning the physical and biological sciences, including genomics, microbial and plant biology, analytical chemistry, computational biology and bioinformatics, and engineering. Institutional partners include DOE national laboratories, universities, private companies, and nonprofit organizations.

  14. Supporting Your Research at Ohio State Office of Research

    E-Print Network [OSTI]

    ­ Randy Moses · Food, Agricultural, & Environmental Sciences ­ Steve Slack · Law ­ Donald Tobin · Medicine at Ohio State Office of Research Research Support Resources Visit the Office of Research web site

  15. Sandia National Laboratories: Research: Research Foundations

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level: National5Sales for4,645 3,625 1,006 492 742EnergyOnItemResearch > TheNuclearHomeland and NuclearReportMaterials ScienceResearch

  16. Research Form | Photosynthetic Antenna Research Center

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    AFDC Printable Version Share this resource Send a link to EERE: Alternative Fuels Data Center Home Page to someone by E-mail Share EERE: Alternative Fuels Data Center Home Page on Facebook Tweet about EERE: Alternative Fuels Data Center Home Page on Twitter Bookmark EERE: Alternative1 First Use of Energy for All Purposes (Fuel and Nonfuel), 2002; Level:Energy: Grid Integration Redefining What's PossibleRadiation Protection Technical s o Freiberge s 3 % A PB 2 7 7Research Form Research Form

  17. RESEARCH PERSONNEL AND ENGINEERING STAFF

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Physicist Dennis Utley, Research Associate (25%) Computer Systems Staff Robert Burch, Jr., Research Associate John C. Hagel, Assoc. Research Scientist (50%) Maxim...

  18. Sponsored Research | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Research and Development Agreement A Cooperative Research and Development Agreement (CRADA) defines and governs an Argonne-industry collaborative research relationship with the...

  19. 18 Research Activities 2012 Research Frontiers

    E-Print Network [OSTI]

    Takada, Shoji

    the changing process of people's lives under globalization and examine its links with the current socio that understanding India will shed light upon a path towards a diversity-enhancing globalization. INDAS is keen undertakes research on Islamic law and economics, including the recently developed Islamic economy

  20. 2009 SEAri Annual Research Summit Research Topic

    E-Print Network [OSTI]

    de Weck, Olivier L.

    Massachusetts Institute of Technology 6 Tradespace Exploration Paradigm: Avoiding Point Designs Cost Utility, 2009 Cambridge, MA Massachusetts Institute of Technology #12;seari.mit.edu SEAri Annual Research Summit © 2009 Massachusetts Institute of Technology 2 Tradespace Exploration (TSE) · Model-based, high