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Sample records for molecular biology university

  1. Structural Molecular Biology, SSRL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Workshops & Summer Schools Summer Students Structural Molecular Biology Illuminating ... major experimental driver for structural biology research, serving the needs of a large ...

  2. Structural Molecular Biology, SSRL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Molecular Biology Group hosted a 3-day comprehensive workshop on the use of non-crystalline small-angle x-ray scattering and diffraction techniques in structural biology research. ...

  3. Structural Molecular Biology, SSRL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Our Mission Our Mission The SSRL Structural Molecular Biology program operates as a integrated resource and has three primary areas (or cores) of technological research and ...

  4. Ringleader: Jay Nix, Beamline Director for the Molecular Biology Consortium

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Jay Nix, Beamline Director for the Molecular Biology Consortium Print Jay Nix started started the user program at Beamline 4.2.2 back in 2004, shortly after the Molecular Biology Consortium built the beamline. The macromolecular crystallography beamline is a little different than most at the ALS because it's privately managed by a consortium of 10 Midwest universities that pooled their money together to build the beamline, and now continue to do so to maintain it. Nix serves about 50 labs,

  5. Molecular biology of signal transduction in plants

    SciTech Connect (OSTI)

    Not Available

    1991-01-01

    This volume contains abstracts of oral presentations and poster sessions of the 1991 Cold Springs Harbor Meeting entitled Molecular Biology of Signal Transduction in Plants.

  6. Genetics and molecular biology of breast cancer

    SciTech Connect (OSTI)

    King, M.C.; Lippman, M.

    1992-12-31

    This volume contains the abstracts of oral presentations and poster sessions presented at the Cold Springs Harbor Meeting on Cancer Cells, this meeting entitled Genetics and Molecular Biology of Breast Cancer.

  7. Molecular Mechanism of Biological Proton Transport

    SciTech Connect (OSTI)

    Pomes, R.

    1998-09-01

    Proton transport across lipid membranes is a fundamental aspect of biological energy transduction (metabolism). This function is mediated by a Grotthuss mechanism involving proton hopping along hydrogen-bonded networks embedded in membrane-spanning proteins. Using molecular simulations, the authors have explored the structural, dynamic, and thermodynamic properties giving rise to long-range proton translocation in hydrogen-bonded networks involving water molecules, or water wires, which are emerging as ubiquitous H{sup +}-transport devices in biological systems.

  8. Frontiers of NMR in Molecular Biology

    SciTech Connect (OSTI)

    1999-08-25

    NMR spectroscopy is expanding the horizons of structural biology by determining the structures and describing the dynamics of blobular proteins in aqueous solution, as well as other classes of proteins including membrane proteins and the polypeptides that form the aggregates diagnostic of prion and amyloid diseases. Significant results are also emerging on DNA and RNA oligomers and their complexes with proteins. This meeting focused attention on key structural questions emanating from molecular biology and how NMR spectroscopy can be used to answer them.

  9. Ringleader: Jay Nix, Beamline Director for the Molecular Biology...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    the Molecular Biology Consortium Print Jay Nix started started the user program at Beamline 4.2.2 back in 2004, shortly after the Molecular Biology Consortium built the beamline. ...

  10. Ringleader: Jay Nix, Beamline Director for the Molecular Biology...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Jay Nix, Beamline Director for the Molecular Biology Consortium Print Jay Nix started started the user program at Beamline 4.2.2 back in 2004, shortly after the Molecular Biology ...

  11. 2009 Archaea: Ecology, Metabolism & Molecular Biology GRC

    SciTech Connect (OSTI)

    Dr. Julie Maupin- Furlow

    2009-07-26

    Archaea, one of three major evolutionary lineages of life, are a fascinating and diverse group of microbes with deep roots overlapping those of eukaryotes. The focus of the 'Archaea: Ecology Metabolism & Molecular Biology' GRC conference expands on a number of emerging topics highlighting new paradigms in archaeal metabolism, genome function and systems biology; information processing; evolution and the tree of life; the ecology and diversity of archaea and their viruses; and industrial applications. The strength of this conference lies in its ability to couple a field with a rich history in high quality research with new scientific findings in an atmosphere of stimulating exchange. This conference remains an excellent opportunity for younger scientists to interact with world experts in this field.

  12. 2011 Archaea: Ecology, Metabolism, & Molecular Biology

    SciTech Connect (OSTI)

    Keneth Stedman

    2011-08-05

    Archaea, one of three major evolutionary lineages of life, are a fascinating and diverse group of microbes with deep roots overlapping those of eukaryotes. The focus of the 'Archaea: Ecology Metabolism & Molecular Biology' GRC conference expands on a number of emerging topics highlighting new paradigms in archaeal metabolism, genome function and systems biology; information processing; evolution and the tree of life; the ecology and diversity of archaea and their viruses. The strength of this conference lies in its ability to couple a field with a rich history in high quality research with new scientific findings in an atmosphere of stimulating exchange. This conference remains an excellent opportunity for younger scientists to interact with world experts in this field.

  13. 2010 Plant Molecular Biology Gordon Research Conference

    SciTech Connect (OSTI)

    Michael Sussman

    2010-07-23

    The Plant Molecular Biology Conference has traditionally covered a breadth of exciting topics and the 2010 conference will continue in that tradition. Emerging concerns about food security have inspired a program with three main themes: (1) genomics, natural variation and breeding to understand adaptation and crop improvement, (2) hormonal cross talk, and (3) plant/microbe interactions. There are also sessions on epigenetics and proteomics/metabolomics. Thus this conference will bring together a range of disciplines, will foster the exchange of ideas and enable participants to learn of the latest developments and ideas in diverse areas of plant biology. The conference provides an excellent opportunity for individuals to discuss their research because additional speakers in each session will be selected from submitted abstracts. There will also be a poster session each day for a two-hour period prior to dinner. In particular, this conference plays a key role in enabling students and postdocs (the next generation of research leaders) to mingle with pioneers in multiple areas of plant science.

  14. Third international congress of plant molecular biology: Molecular biology of plant growth and development

    SciTech Connect (OSTI)

    Hallick, R.B.

    1995-02-01

    The Congress was held October 6-11, 1991 in Tucson with approximately 3000 scientists attending and over 300 oral presentations and 1800 posters. Plant molecular biology is one of the most rapidly developing areas of the biological sciences. Recent advances in the ability to isolate genes, to study their expression, and to create transgenic plants have had a major impact on our understanding of the many fundamental plant processes. In addition, new approaches have been created to improve plants for agricultural purposes. This is a book of presentation and posters from the conference.

  15. Molecular biology of signal transduction in plants. Abstracts

    SciTech Connect (OSTI)

    Not Available

    1991-12-31

    This volume contains abstracts of oral presentations and poster sessions of the 1991 Cold Springs Harbor Meeting entitled Molecular Biology of Signal Transduction in Plants.

  16. Genetics and Molecular Biology of Hydrogen Metabolism in Sulfate...

    Office of Scientific and Technical Information (OSTI)

    Title: Genetics and Molecular Biology of Hydrogen Metabolism in Sulfate-Reducing Bacteria The degradation of our environment and the depletion of fossil fuels make the exploration ...

  17. Overview of selected molecular biological databases

    SciTech Connect (OSTI)

    Rayl, K.D.; Gaasterland, T.

    1994-11-01

    This paper presents an overview of the purpose, content, and design of a subset of the currently available biological databases, with an emphasis on protein databases. Databases included in this summary are 3D-ALI, Berlin RNA databank, Blocks, DSSP, EMBL Nucleotide Database, EMP, ENZYME, FSSP, GDB, GenBank, HSSP, LiMB, PDB, PIR, PKCDD, ProSite, and SWISS-PROT. The goal is to provide a starting point for researchers who wish to take advantage of the myriad available databases. Rather than providing a complete explanation of each database, we present its content and form by explaining the details of typical entries. Pointers to more complete ``user guides`` are included, along with general information on where to search for a new database.

  18. STRUCTURAL BIOLOGY AND MOLECULAR MEDICINE RESEARCH PROGRAM (LSBMM)

    SciTech Connect (OSTI)

    Eisenberg, David S.

    2008-07-15

    The UCLA-DOE Institute of Genomics and Proteomics is an organized research unit of the University of California, sponsored by the Department of Energy through the mechanism of a Cooperative Agreement. Today the Institute consists of 10 Principal Investigators and 7 Associate Members, developing and applying technologies to promote the biological and environmental missions of the Department of Energy, and 5 Core Technology Centers to sustain this work. The focus is on understanding genomes, pathways and molecular machines in organisms of interest to DOE, with special emphasis on developing enabling technologies. Since it was founded in 1947, the UCLA-DOE Institute has adapted its mission to the research needs of DOE and its progenitor agencies as these research needs have changed. The Institute started as the AEC Laboratory of Nuclear Medicine, directed by Stafford Warren, who later became the founding Dean of the UCLA School of Medicine. In this sense, the entire UCLA medical center grew out of the precursor of our Institute. In 1963, the mission of the Institute was expanded into environmental studies by Director Ray Lunt. I became the third director in 1993, and in close consultation with David Galas and John Wooley of DOE, shifted the mission of the Institute towards genomics and proteomics. Since 1993, the Principal Investigators and Core Technology Centers are entirely new, and the Institute has separated from its former division concerned with PET imaging. The UCLA-DOE Institute shares the space of Boyer Hall with the Molecular Biology Institute, and assumes responsibility for the operation of the main core facilities. Fig. 1 gives the organizational chart of the Institute. Some of the benefits to the public of research carried out at the UCLA-DOE Institute include the following: The development of publicly accessible, web-based databases, including the Database of Protein Interactions, and the ProLinks database of genomicly inferred protein function linkages

  19. Computational approaches to discovering semantics in molecular biology

    SciTech Connect (OSTI)

    Lipton, R.J. ); Marr, T.G. . Theoretical Div.); Welsh, J.D. . Dept. of Biology)

    1989-07-01

    One of the central questions of molecular biology is the discovery of the semantics of DNA. This discovery relies in a critical way on a variety of expensive computations. In order to solve these computations, both parallel computers and special-purpose hardware play a major role.

  20. International Conference on the Cell and Molecular Biology of Chlamydomonas

    SciTech Connect (OSTI)

    Dr. Stephen Miller

    2010-06-10

    The 2010 Conference on the Cell and Molecular Biology of Chlamydomonas was held June 6-10 near Boston, MA, and attracted a record 273 participants, 146 from US labs, 10 from Canada, and the remainder from 18 other countries. The single-celled algal protist Chlamydomonas is a key research organism for many investigators, including those who study photosynthesis, cell motility, adaptation to environmental stresses, the evolution of multicellularity, and the production of biofuels. Chlamydomonas researchers gather every two years at a research conference to exchange methods, develop collaborative efforts, disseminate recent findings, and plan large-scale studies to improve the usefulness of this unique research organism. This conference provides the only opportunity for Chlamydomonas scientists who work on different research problems to meet face to face, and greatly speeds progress in their respective fields. An important function of these Chlamydomonas conferences is to promote and showcase the work of younger scientists, and to attract new investigators into the Chlamydomonas community. DOE award SC0004085 was used to offset the travel and registration costs for 18 young investigators, 9 of whom were women, including one African American. Most of these scientists would not have been able to attend the conference without DOE support. A total of 208 research presentations were made at the meeting, 80 talks (63 presented by students, postdocs, and pre-tenured faculty) and 128 posters. Cell motility and biofuels/metabolism were the best-represented research areas, with a total of 77 presentations. This fact underscores the growing importance of Chlamydomonas as a research and production tool in the rapidly expanding world of biofuels research. A total of 28 talks and posters were presented on the topics of photosynthesis and stress responses, which were among the next best-represented research areas. As at several recent Chlamydomonas meetings, important advances were

  1. Molecular biology of Homo sapiens: Abstracts of papers presented at the 51st Cold Spring Harbor symposium on quantitative biology

    SciTech Connect (OSTI)

    Watson, J.D.; Siniscalco, M.

    1986-01-01

    This volume contains abstracts of papers presented at the 51st Cold Springs Harbor Symposium on Quantitative Biology. The topic for this meeting was the ''Molecular Biology of Homo sapiens.'' Sessions were entitled Human Gene Map, Human Cancer Genes, Genetic Diagnosis, Human Evolution, Drugs Made Off Human Genes, Receptors, and Gene Therapy. (DT)

  2. 2012 PLANT MOLECULAR BIOLOGY GORDON RESEARCH CONFERENCE, JULY 15-20, 2012

    SciTech Connect (OSTI)

    Sussman, Michael

    2013-07-20

    The 2012 Gordon Conference on Plant Molecular Biology will present cutting-edge research on molecular aspects of plant growth and development, with particular emphasis on recent discoveries in molecular mechanisms involved with plant signaling systems. The Conference will feature a wide range of topics in plant molecular biology including hormone receptors and early events in hormone signaling, plant perception of and response to plant pathogen and symbionts, as well as technological and biological aspects of epigenomics particularly as it relates to signaling systems that regulate plant growth and development. Genomic approaches to plant signaling will be emphasized, including genomic profiling technologies for quantifying various biological subsystems, such as the epigenome, transcriptome, phosphorylome, and metabolome. The meeting will include an important session devoted to answering the question, "What are the biological and technological limits of plant breeding/genetics, and how can they be solved"?

  3. 2012 CELLULAR & MOLECULAR FUNGAL BIOLOGY GORDON RESEARCH CONFERENCE, JUNE 17 - 22, 2012

    SciTech Connect (OSTI)

    Judith Berman

    2012-06-22

    The Gordon Research Conference on CELLULAR & MOLECULAR FUNGAL BIOLOGY was held at Holderness School, Holderness New Hampshire, June 17 - 22, 2012. The 2012 Gordon Conference on Cellular and Molecular Fungal Biology (CMFB) will present the latest, cutting-edge research on the exciting and growing field of molecular and cellular aspects of fungal biology. Topics will range from yeast to filamentous fungi, from model systems to economically important organisms, and from saprophytes and commensals to pathogens of plants and animals. The CMFB conference will feature a wide range of topics including systems biology, cell biology and morphogenesis, organismal interactions, genome organisation and regulation, pathogenesis, energy metabolism, biomass production and population genomics. The Conference was well-attended with 136 participants. Gordon Research Conferences does not permit publication of meeting proceedings.

  4. Workshop in computational molecular biology, April 15, 1991--April 14, 1994

    SciTech Connect (OSTI)

    Tavare, S.

    1995-04-12

    Funds from this award were used to the Workshop in Computational Molecular Biology, `91 Symposium entitled Interface: Computing Science and Statistics, Seattle, Washington, April 21, 1991; the Workshop in Statistical Issues in Molecular Biology held at Stanford, California, August 8, 1993; and the Session on Population Genetics a part of the 56th Annual Meeting, Institute of Mathematical Statistics, San Francisco, California, August 9, 1993.

  5. Genetics and Molecular Biology of Hydrogen Metabolism in Sulfate-Reducing

    Office of Scientific and Technical Information (OSTI)

    Bacteria (Technical Report) | SciTech Connect Genetics and Molecular Biology of Hydrogen Metabolism in Sulfate-Reducing Bacteria Citation Details In-Document Search Title: Genetics and Molecular Biology of Hydrogen Metabolism in Sulfate-Reducing Bacteria The degradation of our environment and the depletion of fossil fuels make the exploration of alternative fuels evermore imperative. Among the alternatives is biohydrogen which has high energy content by weight and produces only water when

  6. Frontiers of Plant Cell Biology: Signals and Pathways, System-Based Approaches 22nd Symposium in Plant Biology (University of California-Riverside)

    SciTech Connect (OSTI)

    Minorsky, Peter V.

    2003-06-01

    The symposium ''Frontiers of Plant Cell Biology: Signals and Pathways, Systems-Based Approaches'' was held January 15-18, 2003 at the Riverside Convention Center in Riverside, California. The host organization for the symposium was the Center for Plant Cell Biology (CEPCEB) at the University of California, Riverside (UCR). The meeting, focusing on systems-based approaches to plant cell biology research, was the first of this kind in the field of plant biology. The speakers and nearly 100 posters placed emphasis on recent developments in plant cellular biology and molecular genetics, particularly those employing emerging genomic tools, thereby sharing the most current knowledge in the field and stimulating future advances. In attendance were many well-established scientists and young investigators who approach plant cell biology from different but complementary conceptual and technical perspectives. Indeed, many disciplines are converging in the field of cell biology, producing synergies that will enable plant scientists to determine the function of gene products in the context of living cells in whole organisms. New, cross-disciplinary collaborations, as well as the involvement of computer scientists and chemists in plant biology research, are likely additional outcomes of the symposium. The program included 39 invited session speakers and workshop/panel speakers. Sessions were convened on the following themes: Cell-Cell Communication; Protein Trafficking; Cell Surface, Extracellular Matrix and Cell Wall; Signal Transduction; Signal Transduction and Proteosome; and Systems-Based Approaches to Plant Cell Biology. Workshops on Chemical Genetics and Visual Microscopy were also presented. Abstracts from each of the speaker presentations, as well as the posters presented at the meeting were published in a program booklet given to the 239 faculty members, researchers, postdoctoral scientists and graduate students in attendance. The booklet thus serves as a reference for

  7. Recent advances in yeast molecular biology: recombinant DNA. [Lead abstract

    SciTech Connect (OSTI)

    Not Available

    1982-09-01

    Separate abstracts were prepared for the 25 papers presented at a workshop focusing on chromosomal structure, gene regulation, recombination, DNA repair, and cell type control, that have been obtained by experimental approaches incorporating the new technologies of yeast DNA transformation, molecular cloning, and DNA sequence analysis. (KRM)

  8. Modeling human risk: Cell & molecular biology in context

    SciTech Connect (OSTI)

    1997-06-01

    It is anticipated that early in the next century manned missions into outer space will occur, with a mission to Mars scheduled between 2015 and 2020. However, before such missions can be undertaken, a realistic estimation of the potential risks to the flight crews is required. One of the uncertainties remaining in this risk estimation is that posed by the effects of exposure to the radiation environment of outer space. Although the composition of this environment is fairly well understood, the biological effects arising from exposure to it are not. The reasons for this are three-fold: (1) A small but highly significant component of the radiation spectrum in outer space consists of highly charged, high energy (HZE) particles which are not routinely experienced on earth, and for which there are insufficient data on biological effects; (2) Most studies on the biological effects of radiation to date have been high-dose, high dose-rate, whereas in space, with the exception of solar particle events, radiation exposures will be low-dose, low dose-rate; (3) Although it has been established that the virtual absence of gravity in space has a profound effect on human physiology, it is not clear whether these effects will act synergistically with those of radiation exposure. A select panel will evaluate the utilizing experiments and models to accurately predict the risks associated with exposure to HZE particles. Topics of research include cellular and tissue response, health effects associated with radiation damage, model animal systems, and critical markers of Radiation response.

  9. Inhibition Of Molecular And Biological Processes Using Modified Oligonucleotides

    DOE Patents [OSTI]

    Kozyavkin, Sergei A.; Malykh, Andrei G.; Polouchine, Nikolai N.; Slesarev, Alexei I.

    2003-04-15

    A method of inhibiting at least one molecular process in a sample, comprising administering to the sample an oligonucleotide or polynucleotide containing at least one monomeric unit having formula (I): wherein A is an organic moiety, n is at least 1, and each X is independently selected from the group consisting of --NRCOCONu, --NHCOCR.sub.2 CR.sub.2 CONu, --NHCOCR.dbd.CRCONu, and --NHCOSSCONu, wherein each R independently represents H or a substituted or unsubstituted alkyl group, and Nu represents a nucleophile, or a salt of the compound.

  10. Facilities for exploring molecular biology databases on the Web: A comparative study

    SciTech Connect (OSTI)

    Markowitz, V.M.; Chen, I.M.A.; Kosky, A.S.; Szeto, E.

    1996-12-31

    We discuss criteria for evaluating and comparing the main facilities provided by molecular biology databases (MBDs) for exploring (that is, retrieving and interpreting data) on the Web. We use these criteria for examining the facilities supported by typical MBDs such as Genbank, AtDB, GSDB, GDB, and MGD (as of September 5, 1996). 19 refs.

  11. Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biology @WIPP Life Begins at 250,000,000 Years WIPP's underground isn't just suited for physics experiments aiming to unlock the mysteries of the Universe, it is also a perfect "dig site" for biologists wanting to chronicle the history of life. 250 million years ago, the area around WIPP was all part of the Permian Sea. Today, the salt beds that make up the WIPP underground provide a time capsule, of sorts, to this ancient era. Researchers have uncovered ancient bacteria, cellulose and

  12. Molecular biology in marine science: Scientific questions, technological approaches, and practical implications

    SciTech Connect (OSTI)

    1994-12-31

    This report describes molecular techniques that could be invaluable in addressing process-oriented problems in the ocean sciences that have perplexed oceanographers for decades, such as understanding the basis for biogeochemical processes, recruitment processes, upper-ocean dynamics, biological impacts of global warming, and ecological impacts of human activities. The coupling of highly sophisticated methods, such as satellite remote sensing, which permits synoptic monitoring of chemical, physical, and biological parameters over large areas, with the power of modern molecular tools for ``ground truthing`` at small scales could allow scientists to address questions about marine organisms and the ocean in which they live that could not be answered previously. Clearly, the marine sciences are on the threshold of an exciting new frontier of scientific discovery and economic opportunity.

  13. Molecular Biology for the Environment: an EC-US hands-on Course in Environmental Biotechnology

    SciTech Connect (OSTI)

    Victor de Lorenzo; Juan Luis Ramos; Jerome Kukor; Gerben J. Zylstra

    2004-02-15

    One of the central goals of this activity is to bring together young scientists (at the late Ph.D. or early postdoctoral stages of their careers) in a forum that should result in future collaborations. The course is designed to give scientists hands-on experience in modern, up-to-date biotechnological methods at the interface between molecular biology and environmental biotechnology for the analysis of microorganisms and their activities with regard to the remediation of pollutants in the environment.

  14. Plant Molecular Biology 2008 Gordon Research Conference - July 13-18, 2008

    SciTech Connect (OSTI)

    Richard M. Amasino

    2009-08-28

    The Plant Molecular Biology Conference has traditionally covered a breadth of exciting topics and the 2008 conference will continue in that tradition. There will be sessions on metabolism; new methods to study genomes, proteomes and metabolomes; plant-microbe interactions; plant hormones; epigenetics. A new topic for the conference this year will be bioenergy. Thus this conference will bring together a range of disciplines to foster the exchange ideas and to permit the participants to learn of the latest developments and ideas in diverse areas of plant biology. The conference provides an excellent opportunity for individuals to discuss their research because additional speakers in each session will be selected from submitted abstracts. There will also be a poster session each day for a two-hour period prior to dinner.

  15. FINAL REPORT: DOE CONTRACT NUMBER FG0205ER64026 Biological Neutron Scattering: A Collaboration with the Oak Ridge Center for Structural Molecular Biology

    SciTech Connect (OSTI)

    Jill Trewhella

    2011-01-12

    The overarching goal of this project was to promote applications of small-angle scattering in structural molecular biology by providing model examples of cutting edge applications that demonstrate the unique capabilities and potential of the DOE national user facilities at Oak Ridge, especially the newly commissioned BioSANS. The approach taken was three-fold: (1) to engage in high impact collaborative research projects that would benefit from small-angle neutron scattering to both demonstrate the power of the technique while expanding the potential user community; (2) to provide access to scattering facilities established at the University of Utah to as broad a set of researchers as possible to increase the expertise in small-angle scattering generally; and (3) to develop new methods and tools for small-angle scattering. To these ends, three major research collaborations were pursued that resulted in a significant body of published work where neutron scattering and contrast variation played a major role. These major collaborations involved studies of protein complexes involved in (1) bacterial transcription regulation and adaptive response (a DOE/BER priority area); (2) regulation of cardiac muscle; and (3) neuronal disorders. In addition, to broaden the impact of the project, smaller collaborative efforts were supported that used either small-angle X-ray or neutron scattering. Finally, the DOE supported facilities at the University of Utah were made available to researchers on a service basis and a number of independent groups took advantage of this opportunity. In all of this work, there was an emphasis on the training of students and post docs in scattering techniques, and a set of publications (a book chapter, a review, and an encyclopedia article) were produced to guide the non-specialist potential user of scattering techniques in successful applications of the techniques. We also developed a suite of user friendly web-based computational tools currently

  16. 2010 CELL AND MOLECULAR FUNGAL BIOLOGY GORDON RESEARCH CONFERENCE, JUNE 13-18, 2010

    SciTech Connect (OSTI)

    Michelle Momany

    2010-06-18

    The Cellular and Molecular Fungal Biology Conference provides a forum for presentation of the latest advances in fungal research with an emphasis on filamentous fungi. This open-registration scientific meeting brings together the leading scientists from academia, government and industry to discuss current research results and future directions at Holderness School, an outstanding venue for scientific interaction. A key objective of the conference is to foster interaction among scientists working on model fungi such as Saccharomyces cerevisiae, Schizosaccharomyces pombe, Neurospora crassa and Aspergillus nidulans and scientists working on a variety of filamentous fungi whose laboratory tractability is often inversely proportional to their medical, industrial or ecological importance. Sessions will be devoted to Systems Biology, Fungi and Cellulosic Biomass, Small RNAs, Population Genomics, Symbioses, Pathogenesis, Membrane Trafficking and Polarity, and Cytoskeleton and Motors. A session will also be devoted to hot topics picked from abstracts. The CMFB conference provides a unique opportunity to examine the breadth of fungal biology in a small meeting format that encourages in-depth discussion among the attendees.

  17. Theoretical Biology and Biophysics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Theoretical Biology and Biophysics Modeling biological systems and analysis and informatics of molecular and cellular biological data Mathematical BiologyImmunology Fundamental ...

  18. WHOLE CELL TOMOGRAPHY/MOLECULAR BIOLOGY/STRUCTURAL BIOLOGY: Affordable x-ray microscopy with nanoscale resolution

    SciTech Connect (OSTI)

    Evans, James E.; Blackborow, Paul; Horne, Stephen J.; Gelb, Jeff

    2013-03-01

    Biological research spans 10 orders of magnitude from angstroms to meters. While electron microscopy can reveal structural details at most of these spatial length scales, transmission electron tomography only reliably reconstructs three-dimensional (3-D) volumes of cellular material with a spatial resolution between 1-5 nm from samples less than 500 nm thick1. Most biological cells are 2-30 times thicker than this threshold, which means that a cell must be cut into consecutive slices with each slice reconstructed individually in order to approximate the contextual information of the entire cell. Fortunately, due to a larger penetration depth2, X-ray computed tomography bypasses the need to physically section a cell and enables imaging of intact cells and tissues on the micrometer or larger scale with tens to hundreds of nanometer spatial resolution. While the technique of soft x-ray microscopy has been extensively developed in synchrotron facilities, advancements in laboratory x-ray source designs now increase its accessibility by supporting commercial systems suitable for a standard laboratory. In this paper, we highlight a new commercial compact cryogenic soft x-ray microscope designed for a standard laboratory setting and explore its capabilities for mesoscopic investigations of intact prokaryotic and eukaryotic cells.

  19. Molecular Dynameomics

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Dynameomics Molecular Dynameomics DaggettHiResWhitebg.png Key Challenges: Perform molecular dynamics simulations to characterize both native (i.e. biologically active) and...

  20. Universal Biology, the Genetic

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Cooperation | National Nuclear Security Administration | (NNSA) United States and the Republic of Korea Sign Agreement for Civil Nuclear Cooperation June 15, 2015 Washington, DC - Today Secretary of Energy Ernest J. Moniz and Korean Foreign Minister Yun signed the successor United States - Republic of Korea Agreement for Civil Nuclear Cooperation, or 123 Agreement, as they are referred to in the United States. The United States and the Republic of Korea (ROK) are world leaders in civil

  1. Structural Molecular Biology, SSRL

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Science Highlights Science Highlights Structure of Chinese Herbal-based Medicine Captured by ATP on a Human tRNA Synthetase For approximately 2,000 years, the Chinese have been ...

  2. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    sources, as well as lasers that can be used in total internal reflectance mode (TIRF). ... to aid in work with biomolecules, microbes, molecular biology techniques and cell culture. ...

  3. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Facility RLGarcia@lbl.gov 510.486.4125 Biography Education B.A. Molecular Biology, Scripps College, Claremont, CA, 2005 Previous Professional Positions Principal...

  4. University Partners Panel

    Office of Energy Efficiency and Renewable Energy (EERE)

    Matt Tirrell, Pritzker Director and Professor, Institute for Molecular Engineering, University of Chicago Thomas Glasmacher, Facility for Rare Isotope Beams (FRIB) Project Manager, Michigan State University

  5. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    NEWS Subatomic Microscopy Key to Building New Classes of Materials Molecular Foundry users from Penn State University and Cornell University have worked with staff to describe the first atomic scale evidence for strain-induced ferroelectricity in a layered oxide. [MORE] Molecular Foundry User Featured in MIT's Technology Review Cyclotron Road's Kendra Kuhl Featured in '35 Innovators Under 35' for 2016. [MORE] Foundry Fall Seminar Series Begins September 13 The next Molecular Foundry seminar

  6. Automated insertion of sequences into a ribosomal RNA alignment: An application of computational linguistics in molecular biology

    SciTech Connect (OSTI)

    Taylor, R.C.

    1991-11-01

    This thesis involved the construction of (1) a grammar that incorporates knowledge on base invariancy and secondary structure in a molecule and (2) a parser engine that uses the grammar to position bases into the structural subunits of the molecule. These concepts were combined with a novel pinning technique to form a tool that semi-automates insertion of a new species into the alignment for the 16S rRNA molecule (a component of the ribosome) maintained by Dr. Carl Woese's group at the University of Illinois at Urbana. The tool was tested on species extracted from the alignment and on a group of entirely new species. The results were very encouraging, and the tool should be substantial aid to the curators of the 16S alignment. The construction of the grammar was itself automated, allowing application of the tool to alignments for other molecules. The logic programming language Prolog was used to construct all programs involved. The computational linguistics approach used here was found to be a useful way to attach the problem of insertion into an alignment.

  7. Automated insertion of sequences into a ribosomal RNA alignment: An application of computational linguistics in molecular biology

    SciTech Connect (OSTI)

    Taylor, R.C.

    1991-11-01

    This thesis involved the construction of (1) a grammar that incorporates knowledge on base invariancy and secondary structure in a molecule and (2) a parser engine that uses the grammar to position bases into the structural subunits of the molecule. These concepts were combined with a novel pinning technique to form a tool that semi-automates insertion of a new species into the alignment for the 16S rRNA molecule (a component of the ribosome) maintained by Dr. Carl Woese`s group at the University of Illinois at Urbana. The tool was tested on species extracted from the alignment and on a group of entirely new species. The results were very encouraging, and the tool should be substantial aid to the curators of the 16S alignment. The construction of the grammar was itself automated, allowing application of the tool to alignments for other molecules. The logic programming language Prolog was used to construct all programs involved. The computational linguistics approach used here was found to be a useful way to attach the problem of insertion into an alignment.

  8. (Biological dosimetry)

    SciTech Connect (OSTI)

    Sega, G.A.

    1990-11-06

    The traveler participated in an International Symposium on Trends in Biological Dosimetry and presented an invited paper entitled, Adducts in sperm protamine and DNA vs mutation frequency.'' The purpose of the Symposium was to examine the applicability of new methods to study quantitatively the effects of xenobiotic agents (radiation and chemicals) on molecular, cellular and organ systems, with special emphasis on human biological dosimetry. The general areas covered at the meeting included studies on parent compounds and metabolites; protein adducts; DNA adducts; gene mutations; cytogenetic end-points and reproductive methods.

  9. Autofermentative Biological Hydrogen Production by Cyanobacteria

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    BioSolarH 2 Autofermentative biological hydrogen production by cyanobacteria G.C. Dismukes Rutgers University Waksman Institute and Department of Chemistry & Chemical Biology ...

  10. Report on the research conducted under the funding of the Sloan foundation postdoctoral fellowship in Computational Molecular Biology [Systematic study of protein-protein complexes] Final report

    SciTech Connect (OSTI)

    Sheinerman, Felix

    2001-06-01

    A central question in molecular biology is what structural features are common at protein-protein interfaces and what energetic factors define the affinity and specificity of protein-protein association. Analysis of structural and mutational data on protein-protein interfaces revealed that protein-protein interfaces of different functional classes contain many more energetically important charged and polar residues than was previously thought. Since, in the context of protein folding studies, polar interactions are believed to destabilize the folded proteins, this observation raised the question as to the forces that determine the stability of protein complexes. To investigate this issue in detail, the authors developed a number of partitioning schemes that allowed them to investigate the role of selected residues, ion pairs, and networks of polar interactions in protein-protein association. The methods developed were applied to the analysis of four different protein-protein interfaces: the ribonuclease barnase and its inhibitor barstar, the human growth hormone and its receptor, subtype N9 influenze virus neuraminidase and NC41 antibody, and the Ras Binding Domain of kinase cRaf and a Ras homologue Rap1A. The calculations revealed a surprising variability in how polar interactions affect the stability of different complexes. The finding that positions of charged and polar residues on protein-protein interfaces are optimized with respect to electrostatic interactions suggests that this property can be employed for the discrimination between native conformations and trial complexes generated by a docking algorithm. Analysis indicated the presence of SH2 domains in Janus family of non-receptor protein tyrosine kinases.

  11. (Biological dosimetry)

    SciTech Connect (OSTI)

    Preston, R.J.

    1990-12-17

    The traveler attended the 1st International Conference on Biological Dosimetry in Madrid, Spain. This conference was organized to provide information to a general audience of biologists, physicists, radiotherapists, industrial hygiene personnel and individuals from related fields on the current ability of cytogenetic analysis to provide estimates of radiation dose in cases of occupational or environmental exposure. There is a growing interest in Spain in biological dosimetry because of the increased use of radiation sources for medical and occupational uses, and with this the anticipated and actual increase in numbers of overexposure. The traveler delivered the introductory lecture on Biological Dosimetry: Mechanistic Concepts'' that was intended to provide a framework by which the more applied lectures could be interpreted in a mechanistic way. A second component of the trip was to provide advice with regard to several recent cases of overexposure that had been or were being assessed by the Radiopathology and Radiotherapy Department of the Hospital General Gregorio Maranon'' in Madrid. The traveler had provided information on several of these, and had analyzed cells from some exposed or purportedly exposed individuals. The members of the biological dosimetry group were referred to individuals at REACTS at Oak Ridge Associated Universities for advice on follow-up treatment.

  12. Molecular and biological characterization of the 5 human-bovine rotavirus (WC3)-based reassortant strains of the pentavalent rotavirus vaccine, RotaTeq (registered)

    SciTech Connect (OSTI)

    Matthijnssens, Jelle; Joelsson, Daniel B.; Warakomski, Donald J.; Zhou, Tingyi; Mathis, Pamela K.; Maanen, Marc-Henri van; Ranheim, Todd S.; Ciarlet, Max

    2010-08-01

    RotaTeq (registered) is a pentavalent rotavirus vaccine that contains five human-bovine reassortant strains (designated G1, G2, G3, G4, and P1) on the backbone of the naturally attenuated tissue culture-adapted parental bovine rotavirus (BRV) strain WC3. The viral genomes of each of the reassortant strains were completely sequenced and compared pairwise and phylogenetically among each other and to human rotavirus (HRV) and BRV reference strains. Reassortants G1, G2, G3, and G4 contained the VP7 gene from their corresponding HRV parent strains, while reassortants G1 and G2 also contained the VP3 gene (genotype M1) from the HRV parent strain. The P1 reassortant contained the VP4 gene from the HRV parent strain and all the other gene segments from the BRV WC3 strain. The human VP7s had a high level of overall amino acid identity (G1: 95-99%, G2: 94-99% G3: 96-100%, G4: 93-99%) when compared to those of representative rotavirus strains of their corresponding G serotypes. The VP4 of the P1 reassortant had a high identity (92-97%) with those of serotype P1A[8] HRV reference strains, while the BRV VP7 showed identities ranging from 91% to 94% to those of serotype G6 HRV strains. Sequence analyses of the BRV or HRV genes confirmed that the fundamental structure of the proteins in the vaccine was similar to those of the HRV and BRV references strains. Sequences analyses showed that RotaTeq (registered) exhibited a high degree of genetic stability as no mutations were identified in the material of each reassortant, which undergoes two rounds of replication cycles in cell culture during the manufacturing process, when compared to the final material used to fill the dosing tubes. The infectivity of each of the reassortant strains of RotaTeq (registered) , like HRV strains, did not require the presence of sialic acid residues on the cell surface. The molecular and biologic characterization of RotaTeq (registered) adds to the significant body of clinical data supporting the

  13. California: Breakthrough in Algae Biology | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Breakthrough in Algae Biology California: Breakthrough in Algae Biology January 31, 2014 - 12:00am Addthis Researchers at the Scripps Institution of Oceanography at University of ...

  14. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    SEMINARS ARCHIVE The Molecular Foundry regularly offers seminars and events that feature compelling research and information for those who investigate at the nanoscale. Seminars occur on Tuesdays at 11:00 am, in Building 67, Room 3111 unless otherwise noted. < seminars and events Tuesday, June 28, 2016 at 11am Revealing the Mechanisms of Deformation in Structural Materials Using Advanced Characterization Techniques Mike Mills, The Ohio State University [MORE] Tuesday, June 14, 2016 at 11am

  15. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Emory Chan Brand Staff Scientist, Inorganic Nanostructures EMChan@lbl.gov 510.486.7874 personal website Biography Education Postdoctoral fellow, Molecular Foundry with Dr. Delia Milliron Ph. D., Chemistry, UC Berkeley with Prof. Paul Alivisatos and Prof. Richard Mathies, B. S., Chemistry, Stanford University with Prof. Hongjie Dai Expertise Dr. Chan's expertise lies in the combinatorial and high-throughput synthesis of colloidal inorganic nanoparticles. As part of the Foundry's Combinatorial

  16. Autofermentative Biological Hydrogen Production by Cyanobacteria

    Broader source: Energy.gov [DOE]

    Presentation by Charles Dismukes, Rutgers University, at the Biological Hydrogen Production Workshop held September 24-25, 2013, at the National Renewable Energy Laboratory in Golden, Colorado.

  17. New Types of Unstable Step-Flow Growth on Si(111)-(7x7) during Molecular Beam Epitaxy: Scaling and Universality

    SciTech Connect (OSTI)

    Omi, Hiroo; Homma, Yoshikazu; Tonchev, Vesselin; Pimpinelli, Alberto

    2005-11-18

    New types of unstable homoepitaxial growth of vicinal Si(111)-(7x7) surfaces are studied using ex situ atomic force microscopy. The growth features are two types of step bunching with straight step edges between 700 and 775 deg. C and one type of simultaneous bunching and meandering at 800 deg. C. The results of a quantitative size scaling analysis of the straight steps are discussed from the perspective of universality classes in bunching theory.

  18. Final Report - Montana State University - Microbial Activity...

    Office of Scientific and Technical Information (OSTI)

    Biological and chemical reactions all require diffusive transport of solutes to reaction sites at the molecular scale and accordingly, the success of processes at the meter-scale ...

  19. Biological Safety

    Office of Energy Efficiency and Renewable Energy (EERE)

    The DOE's Biological Safety Program provides a forum for the exchange of best practices, lessons learned, and guidance in the area of biological safety. This content is supported by the Biosurety Executive Team. The Biosurety Executive Team is a DOE-chartered group. The DOE Office of Worker Safety and Health Policy provides administrative support for this group. The group identifies biological safety-related issues of concern to the DOE and pursues solutions to issues identified.

  20. DockingShop: A Tool for Interactive Molecular Docking (Conference...

    Office of Scientific and Technical Information (OSTI)

    Country of Publication: United States Language: English Subject: 59 BASIC BIOLOGICAL ... FEEDBACK; FORECASTING; MOLECULAR STRUCTURE; NAVIGATION; OPTIMIZATION; PROTEINS; ...

  1. Plant Vascular Biology 2010

    SciTech Connect (OSTI)

    Ding, Biao

    2014-11-17

    This grant supported the Second International Conference on Plant Vascular Biology (PVB 2010) held July 24-28, 2010 on the campus of Ohio State University, Columbus, Ohio. Biao Ding (Ohio State University; OSU) and David Hannapel (Iowa State University; ISU) served as co-chairs of this conference. Biao Ding served as the local organizer. PVB is defined broadly here to include studies on the biogenesis, structure and function of transport systems in plants, under conditions of normal plant growth and development as well as of plant interactions with pathogens. The transport systems cover broadly the xylem, phloem, plasmodesmata and vascular cell membranes. The PVB concept has emerged in recent years to emphasize the integrative nature of the transport systems and approaches to investigate them.

  2. Institute for Molecular Engineering | Argonne National Laboratory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Learn more about the Institute for Molecular Engineering. When completed in early 2015, the William Eckhardt Research Center at the University of Chicago will be the home of the Institute of Molecular Engineering. Institute for Molecular Engineering The new Institute for Molecular Engineering explores innovative technologies that address fundamental societal problems through advances in nanoscale manipulation and design at a molecular scale. Addressing Societal Problems with Molecular Science

  3. Michael Levitt and Computational Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Michael Levitt and Computational Biology Resources with Additional Information * Publications Michael Levitt Courtesy of Linda A. Cicero / Stanford News Service Michael Levitt, PhD, professor of structural biology at the Stanford University School of Medicine, has won the 2013 Nobel Prize in Chemistry. ... Levitt ... shares the ... prize with Martin Karplus ... and Arieh Warshel ... "for the development of multiscale models for complex chemical systems." Levitt's work focuses on

  4. Algal Biology Toolbox Workshop Summary Report

    Office of Energy Efficiency and Renewable Energy (EERE)

    The Algal Biology Toolbox Workshop Summary Report summarizes an event hosted by the U.S. Department of Energy’s Bioenergy Technologies Office’s Advanced Algal Systems Program in May 2016. The purpose of the Algal Biology Toolbox Workshop was to collect input from experts in the field of algal biology regarding (1) the current state of algal biological tools, including our understanding of algal biology and biochemistry, available molecular toolboxes, omics databases, and other resources; (2) challenges to developing and applying a full suite of biological tools to improve algae performance and system robustness; and (3) strategies to advance progress toward commercial algal biofuels.

  5. The Development of New User Research Capabilities in Environmental Molecular Science: Workshop Report

    SciTech Connect (OSTI)

    Felmy, Andrew R.; Baer, Donald R.; Fredrickson, Jim K.; Gephart, Roy E.; Rosso, Kevin M.

    2006-10-31

    On August 1, and 2, 2006, 104 scientists representing 40 institutions including 24 Universities and 5 National Laboratories gathered at the W.R. Wiley Environmental Molecular Sciences Laboratory, a National scientific user facility, to outline important science challenges for the next decade and identify major capabilities needed to pursue advanced research in the environmental molecular sciences. EMSL’s four science themes served as the framework for the workshop. The four science themes are 1) Biological Interactions and Interfaces, 2) Geochemistry/Biogeochemistry and Surface Science, 3) Atmospheric Aerosol Chemistry, and 4) Science of Interfacial Phenomena.

  6. PULSE at Stanford University

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Photon Science @ SLAC - LCLS - LUSI - SSRL - PULSE - Stanford University Go Search Home Publications Atomic & Molecular Physics Condensed Matter Physics Single Molecule Imaging Single-Shot Nanoscale Imaging Ultrafast Chemical Processes Ultrafast Magnetic Switching Contact Us Office of Science/U.S. DOE Ultrafast Center PULSE (Photon Ultrafast Laser Science and Engineering) is based on a remarkable new venture at SLAC/Stanford – the construction of the world’s first x-ray free electron

  7. Local Universities

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Universities Local Universities Los Alamos Lab recruits the best minds on the planet and offers job search information and assistance to our dual career spouses or partners. Contact Us dualcareers@lanl.gov The listing of schools, colleges and universities in New Mexico is organized by region. Northern New Mexico Area Espanola Public Schools District (K-12) Los Alamos Public Schools McCurdy Charter School New Mexico School for the Deaf Northern New Mexico Community College Pojoaque Valley Schools

  8. University Research | U.S. DOE Office of Science (SC)

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    University Research Universities Universities Home Interactive Grants Map SC In Your State University Science Highlights University Research News Contact Information Office of Science U.S. Department of Energy 1000 Independence Ave., SW Washington, DC 20585 P: (202) 586-5430 University Research Print Text Size: A A A Subscribe FeedbackShare Page GO 09.02.16University Research Subatomic Microscopy Key to Building New Classes of Materials External link Researchers at Penn State and the Molecular

  9. National Laboratory] Basic Biological Sciences(59) Biological...

    Office of Scientific and Technical Information (OSTI)

    Achievements of structural genomics Terwilliger, Thomas C. Los Alamos National Laboratory Basic Biological Sciences(59) Biological Science Biological Science Abstract Not...

  10. Biological preconcentrator

    DOE Patents [OSTI]

    Manginell, Ronald P.; Bunker, Bruce C.; Huber, Dale L.

    2008-09-09

    A biological preconcentrator comprises a stimulus-responsive active film on a stimulus-producing microfabricated platform. The active film can comprise a thermally switchable polymer film that can be used to selectively absorb and desorb proteins from a protein mixture. The biological microfabricated platform can comprise a thin membrane suspended on a substrate with an integral resistive heater and/or thermoelectric cooler for thermal switching of the active polymer film disposed on the membrane. The active polymer film can comprise hydrogel-like polymers, such as poly(ethylene oxide) or poly(n-isopropylacrylamide), that are tethered to the membrane. The biological preconcentrator can be fabricated with semiconductor materials and technologies.

  11. EERE Success Story-California: Breakthrough in Algae Biology...

    Broader source: Energy.gov (indexed) [DOE]

    Researchers at the Scripps Institution of Oceanography at University of California, San ... of Algal Research EERE Success Story-California: Breakthrough in Algae Biology Algal ...

  12. Browse by Discipline -- E-print Network Subject Pathways: Biology...

    Office of Scientific and Technical Information (OSTI)

    Biological, and Environmental Engineering, Oregon State University Williams, John M. (John M. Williams) - Petroleum Engineering program, Petroleum Institute (Abu Dhabi) Go ...

  13. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    B.A., Theoretical Physics, Lanzhou University, China, 1986-1990 M.S., Theoretical Physics (General relativity and gauge theory), Lanzhou University, China, 1990-1993, Advisor: ...

  14. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Education 2002 Ph.D., Physics, University College Cork, Ireland 1999 B.Sc., Physics and Mathematics, University College Cork, Ireland Research Interests My research focuses on ...

  15. Howard University Researchers Represented in the E-print Network

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ww.biology.howard.edu FacultyFacultyBiosEckberg.htm Hindman, Neil - Department of Mathematics, Howard University http:mysite.verizon.netnhindman Sitaraman, Sankar -...

  16. Ninth International Workshop on Plant Membrane Biology

    SciTech Connect (OSTI)

    Not Available

    1993-12-31

    This report is a compilation of abstracts from papers which were discussed at a workshop on plant membrane biology. Topics include: plasma membrane ATP-ases; plant-environment interactions, membrane receptors; signal transduction; ion channel physiology; biophysics and molecular biology; vaculor H+ pumps; sugar carriers; membrane transport; and cellular structure and function.

  17. Final report for Conference Support Grant "From Computational Biophysics to Systems Biology - CBSB12"

    SciTech Connect (OSTI)

    Hansmann, Ulrich H.E.

    2012-07-02

    This report summarizes the outcome of the international workshop “From Computational Biophysics to Systems Biology (CBSB12)” which was held June 3-5, 2012, at the University of Tennessee Conference Center in Knoxville, TN, and supported by DOE through the Conference Support Grant 120174. The purpose of CBSB12 was to provide a forum for the interaction between a data-mining interested systems biology community and a simulation and first-principle oriented computational biophysics/biochemistry community. CBSB12 was the sixth in a series of workshops of the same name organized in recent years, and the second that has been held in the USA. As in previous years, it gave researchers from physics, biology, and computer science an opportunity to acquaint each other with current trends in computational biophysics and systems biology, to explore venues of cooperation, and to establish together a detailed understanding of cells at a molecular level. The conference grant of $10,000 was used to cover registration fees and provide travel fellowships to selected students and postdoctoral scientists. By educating graduate students and providing a forum for young scientists to perform research into the working of cells at a molecular level, the workshop adds to DOE's mission of paving the way to exploit the abilities of living systems to capture, store and utilize energy.

  18. Genomics and Systems Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Genomics and Systems Biology LANL leads the world in computational finishing of microbial ... and experimental biology as the foundation of a dynamic systems biology capability. ...

  19. Systems biology approach to bioremediation

    SciTech Connect (OSTI)

    Chakraborty, Romy; Wu, Cindy H.; Hazen, Terry C.

    2012-06-01

    Bioremediation has historically been approached as a ‘black box’ in terms of our fundamental understanding. Thus it succeeds and fails, seldom without a complete understanding of why. Systems biology is an integrated research approach to study complex biological systems, by investigating interactions and networks at the molecular, cellular, community, and ecosystem level. The knowledge of these interactions within individual components is fundamental to understanding the dynamics of the ecosystem under investigation. Finally, understanding and modeling functional microbial community structure and stress responses in environments at all levels have tremendous implications for our fundamental understanding of hydrobiogeochemical processes and the potential for making bioremediation breakthroughs and illuminating the ‘black box’.

  20. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    University Distinguished Teaching Award. Research Interests Organic, Bioorganic, and Materials Chemistry - Self-assembling networks of inorganic nanocrystals from modified...

  1. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Mike Brady ed_barnard Joint Molecular Foundry/ALS Project Scientist mabrady@lbl.gov 510.486.6548

  2. Molecular Science

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Molecular Science NETL's Molecular Science competency provides technology-enabling computational and experimental insight into the atomic-level processes occurring in condensed matter and gas phase systems or at the heterogeneous surface-gas interfaces used for energy applications. Research includes molecular optimization as well as both classical and high-throughput material design, specifically: Molecular Optimization Development and application of new computational approaches in the general

  3. Open University

    ScienceCinema (OSTI)

    None

    2011-04-25

    Michel Pentz est née en Afrique du Sud et venu au Cern en 1957 comme physicien et président de l'associaion du personnel. Il est également fondateur du mouvement Antiapartheid de Genève et a participé à la fondation de l'Open University en Grande-Bretagne. Il nous parle des contextes pédagogiques, culturels et nationaux dans lesquels la méthode peut s'appliquer.

  4. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biological Nanostructures Staff Ron Zuckerman Ron Zuckermann Facility Director rnzuckermann@lbl.gov 510.486.7091 Caroline Ajo-Franklin Caroline Ajo-Franklin Staff Scientist...

  5. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Bachelor's of Science degree in Chemistry from California Polytechnic State University in San Luis Obispo, CA. After a short stint teaching high school chemistry, she joined the...

  6. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    natural sciences and his habilitation in physics performing spectroscopic studies on defects in semiconductors at the University of Cologne, Germany in 1985 and 1990, respectively. ...

  7. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Staff Scientist, Imaging and Manipulation of Nanostructures afweber-bargioni@lbl.gov 510.486.4026 personal website Biography Education University of Konstanz, Germany Physics B.S., ...

  8. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... Deep absorbing porphyrin molecules and their applications in organic solar cells Ke Gao, South China University of Technology Theory of Nanostructured Materials Facility High ...

  9. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Synthesis LMKlivansky@lbl.gov 510.486.4199 Biography Education B.Sc.(HONS) Chemistry, Monash University, Victoria, Australia, 1990 Previous Professional Positions...

  10. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Branden Brough Branden Director of Strategy and External Relations bbrough@lbl.gov 510.486.4206 Biography Branden Brough is the Molecular Foundry's Director of Strategy and...

  11. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    at the Molecular Foundry as a Scientific Engineering Associate since 2007. Expertise Tracy's main focus is assisting users with their research projects (helping design reactions ...

  12. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Liu's research aims to achieve coherent control of functionality and properties across different scales through molecular level design and synthesis. With the developed materials ...

  13. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Jeff Urban of the Molecular. Both of these positions involved the application of his laser physics and chemistry knowledge to implement various spectroscopic imaging techniques. ...

  14. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    User Guide Download the complete Users' Guide (PDF) Submit a Proposal Learn about the Molecular Foundry and its user program Explore Foundry capabilities and plan your proposal...

  15. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Flatter and Faster: Transition Metal Dichalcogendies at the Molecular Foundry (Part II) Brain Imaging and Optical Manipulation Active Nanointerfaces for Electrochemistry SAXS-WAXS...

  16. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Dmitry Soustin dmitry User Program Administrator dsoustin@lbl.gov 510.486.7687 Biography Dmitry Soustin is the Molecular Foundry's User Program Administrator. In this role, Dmitry...

  17. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Theory of Nanostructured Materials jbneaton@lbl.gov 510.486.4527 personal website Biography Jeffrey B. Neaton is Director of the Molecular Foundry, a Department of Energy...

  18. Modern concepts in molecular modeling

    SciTech Connect (OSTI)

    Bajorath, J.; Klein, T.E.

    1996-12-31

    This session focused on the application of computer models and the development and application of various energy functions to study the structure, energetics and dynamics of proteins and their interactions with ligands. These studies provide an exciting view of current developments in computer-aided molecular modeling and theoretical analysis of biological molecules.

  19. Genomics and Systems Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Genomics and Systems Biology Genomics and Systems Biology Los Alamos scientists perform research in functional genomics and structural genomics, and applications for such work ...

  20. Work with Biological Materials

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    cells, viruses), plant or soil samples (USDA quarantines), recombinant DNA, or blood-borne pathogen. Biological Use Authorization The great majority of biological work at...

  1. Micro/nanofabricated environments for synthetic biology

    SciTech Connect (OSTI)

    Collier, Pat [ORNL; Simpson, Michael L [ORNL

    2011-01-01

    A better understanding of how confinement, crowding and reduced dimensionality modulate reactivity and reaction dynamics will aid in the rational and systematic discovery of functionality in complex biological systems. Artificial micro- and nanofabricated structures have helped elucidate the effects of nanoscale spatial confinement and segregation on biological behavior, particularly when integrated with microfluidics, through precise control in both space and time of diffusible signals and binding interactions. Examples of nanostructured interfaces for synthetic biology include the development of cell-like compartments for encapsulating biochemical reactions, nanostructured environments for fundamental studies of diffusion, molecular transport and biochemical reaction kinetics, and regulation of biomolecular interactions as functions of micro- and nanofabricated topological constraints.

  2. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    B.E., & Chuang, H.-h.. Activity-dependent targeting of TRPV1 with a pore-permeating capsaicin analog. Proc. Natl. Acad. Sci. 108, 8497-8500 (2011). link Cohen, B.E. Biological...

  3. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Ralph J. Greenspan, Director, Center for Brain Activity Mapping; Professor of BiologyNeurobiology Section and of Cognitive Science, UC San Diego; Co-Director, Cal-BRAIN. Roger ...

  4. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Agenda March 24, 2016 Lawrence Berkeley National Laboratory AGENDA Registration 8:30 am - 9:00 am The Molecular Foundry's History and Impact 9:00 am - 10:30 am Jeff Neaton, Molecular Foundry Welcome Paul Alivisatos, Berkeley Lab/UC Berkeley The Creation of the Molecular Foundry Michael Witherell, Berkeley Lab Berkeley Lab Impact Brian Schowengerdt, Magic Leap Industry Impact Representative Mike Honda (D-CA) National Impact Break 10:30 am - 11:00 am Session 1: Functional Nanointerfaces 11:00 am -

  5. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biological Nanostructures This facility studies the synthesis, analysis and mimicry of biological nanostructures. Expertise and capabilities are available to develop new materials based on the folding and assembly of sequence-defined, bioinspired polymers (including peptides,,nucleic acids, and peptoids). New biocompatible imaging probes based on organic dyes and functionalized inorganic nanocrystals are being developed and are available to facilitate state-of-the-art bioimaging studies.

  6. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Rechovot, Israel Ph.D. in Chemical Physics, Awarded Finberg prize for outstanding graduate research 1995 Ben-Gurion University of the Negev, Beer-Sheva, Israel M. Sc. in ...

  7. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Senior Scientific Engineering Associate, NCEM csong@lbl.gov 510.486.6751 Biography Education B.S. in Materials Science, Zhejiang University, China M.S. in high Tc superconductor ...

  8. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    He received a B.A. in Mechanical Engineering and Economics from Yale University, and a M.S. and Ph.D. in Materials Science and Engineering from UC Berkeley. Research Interests Dr. ...

  9. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Basic understanding of this nature is required to achieve the mission of the Molecular Foundry, the atomic-level design, creation and control of energy-relevant materials. My group ...

  10. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Seminars occur on Tuesdays at 11:00 am, in Building 67, Room 3111 unless otherwise noted. To be added to the Molecular Foundry's seminar mailing list, please email Jason Sweet. ...

  11. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Meg Holm Meg Senior Administrator mcholm@lbl.gov 510.486.5135 Biography Meg is the Molecular Foundry's Senior Administrator. In this role, she supervises the Foundry budget...

  12. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Alison Hatt allison User Program Director ajhatt@lbl.gov 510.486.7154 Biography Alison Hatt is the Director of the User Program at the Molecular Foundry and a former Foundry...

  13. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Gil Torres Gil Torres gjtorres@lbl.gov 510.486.4395 Biography Gil is the Building Manager for MSD in buildings 62, 66, 2, 30, JCAP and the Molecular Foundry. Gil supports Foundry...

  14. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    See the Foundry's full equipment list Organic and Macromolecular Synthesis Capabilities & Tools Instrument Scheduler Major Instruments and Capabilities AB SCIEX TF4800 MALDI TOF-TOF Mass Spectrometer This instrument is the tandem time-of-flight mass spectrometer systems, providing the excellent level of molecular mass coverage in the range of molecular masses 500 and 150,000 Da, high throughput, and confidence in both qualitative and quantitative analyses. The analyzer combines all of the

  15. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Foundry Molecular Foundry HOME REGISTRATION AGENDA SYMPOSIA POSTERS EXHIBITOR INFO TRAVEL & LODGING Molecular Foundry User Meeting: August 11-12, 2016 This conference focuses on frontier research topics in nanoscale science, providing a forum for discussion and development of new results and ideas. Whether you are a returning user, a prospective user, or someone who is curious about the Foundry, you are encouraged to attend the User Meeting. Participants are invited to submit abstracts for

  16. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Media and Resources MEDIA Molecular Foundry Youtube Channel Berkeley Lab Youtube Channel Berkeley Lab Photo Archive Webcam The Molecular Foundry and its users benefit from its location at Berkeley Lab within the Bay Area's vibrant scientific ecosystem. The expansive views serve to fuel the imagination and build connections among the Foundry's diverse research community. Baycam Click here for a full screen view from our webcam. RESOURCES Style Guide PDF 308 KB Logos Signature Preferred 41 KB ZIP

  17. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Publications Advanced Materials Special Issue » The Molecular Foundry publication database lists peer-reviewed work that has resulted from internal and user research. New publications can be added to the database here. All published work resulting from the use of this facility must acknowledge the Molecular Foundry, regardless of whether Foundry staff are included as authors. Proper acknowledgement text can be found here. Citation Year Facility User Loading data from server

  18. Browse by Discipline -- E-print Network Subject Pathways: Biology...

    Office of Scientific and Technical Information (OSTI)

    L M N O P Q R S T U V W X Y Z Keller, Christopher (Christopher Keller) - Department of Biology, Minot State University Go back to Individual Researchers Collections: A B C D E F G ...

  19. Biological conversion system

    DOE Patents [OSTI]

    Scott, C.D.

    A system for bioconversion of organic material comprises a primary bioreactor column wherein a biological active agent (zymomonas mobilis) converts the organic material (sugar) to a product (alcohol), a rejuvenator column wherein the biological activity of said biological active agent is enhanced, and means for circulating said biological active agent between said primary bioreactor column and said rejuvenator column.

  20. [Studies of biologic activation associated with molecular receptor increase and tumor response in ChL6/L6 protocol patients; Studies in phantoms; Quantitative SPECT; Preclinical studies; and Clinical studies]. DOE annual report, 1994--95

    SciTech Connect (OSTI)

    DeNardo, S.J.

    1995-12-31

    The authors describe results which have not yet been published from their associated studies listed in the title. For the first, they discuss Lym-1 single chain genetically engineered molecules, analysis of molecular genetic coded messages to enhance tumor response, and human dosimetry and therapeutic human use radiopharmaceuticals. Studies in phantoms includes a discussion of planar image quantitation, counts coincidence correction, organ studies, tumor studies, and {sup 90}Y quantitation with Bremsstrahlung imaging. The study on SPECT discusses attenuation correction and scatter correction. Preclinical studies investigated uptake of {sup 90}Y-BrE-3 in mice using autoradiography. Clinical studies discuss image quantitation verses counts from biopsy samples, S factors for radiation dose calculation, {sup 67}Cu imaging studies for lymphoma cancer, and {sup 111}In MoAb imaging studies for breast cancer to predict {sup 90}Y MoAb therapy.

  1. Physics Meets Biology (LBNL Summer Lecture Series)

    ScienceCinema (OSTI)

    Chu, Steve [Director, LBNL

    2011-04-28

    Summer Lecture Series 2006: If scientists could take advantage of the awesomely complex and beautiful functioning of biologys natural molecular machines, their potential for application in many disciplines would be incalculable. Nobel Laureate and Director of the Lawrence Berkeley National Laboratory Steve Chu explores Possible solutions to global warming and its consequences.

  2. Molecular fountain.

    SciTech Connect (OSTI)

    Strecker, Kevin E.; Chandler, David W.

    2009-09-01

    A molecular fountain directs slowly moving molecules against gravity to further slow them to translational energies that they can be trapped and studied. If the molecules are initially slow enough they will return some time later to the position from which they were launched. Because this round trip time can be on the order of a second a single molecule can be observed for times sufficient to perform Hz level spectroscopy. The goal of this LDRD proposal was to construct a novel Molecular Fountain apparatus capable of producing dilute samples of molecules at near zero temperatures in well-defined user-selectable, quantum states. The slowly moving molecules used in this research are produced by the previously developed Kinematic Cooling technique, which uses a crossed atomic and molecular beam apparatus to generate single rotational level molecular samples moving slowly in the laboratory reference frame. The Kinematic Cooling technique produces cold molecules from a supersonic molecular beam via single collisions with a supersonic atomic beam. A single collision of an atom with a molecule occurring at the correct energy and relative velocity can cause a small fraction of the molecules to move very slowly vertically against gravity in the laboratory. These slowly moving molecules are captured by an electrostatic hexapole guiding field that both orients and focuses the molecules. The molecules are focused into the ionization region of a time-of-flight mass spectrometer and are ionized by laser radiation. The new molecular fountain apparatus was built utilizing a new design for molecular beam apparatus that has allowed us to miniaturize the apparatus. This new design minimizes the volumes and surface area of the machine allowing smaller pumps to maintain the necessary background pressures needed for these experiments.

  3. Environmental Molecular Sciences Laboratory (EMSL) | U.S. DOE Office of

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Science (SC) Environmental Molecular Sciences Laboratory (EMSL) Biological and Environmental Research (BER) BER Home About Research Facilities User Facilities Atmospheric Radiation Measurement Climate Research Facility (ARM) Environmental Molecular Sciences Laboratory (EMSL) Joint Genome Institute (JGI) Science Highlights Benefits of BER Funding Opportunities Biological & Environmental Research Advisory Committee (BERAC) Community Resources Contact Information Biological and

  4. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    See the Foundry's full equipment list Research Themes Discovering the Future, Atom by Atom The six-story, 94,000 square-foot Molecular Foundry building at LBNL overlooks the UC Berkeley campus and, from a distance, the San Francisco Bay. Directly adjacent to the Foundry is the NCEM complex that was established in 1983 to maintain a forefront research center for electron microscopy with state-of-the-art instrumentation and expertise. Merged with the Molecular Foundry in 2014 to take advantage of

  5. Final Report for Integrated Multiscale Modeling of Molecular Computing Devices

    SciTech Connect (OSTI)

    Glotzer, Sharon C.

    2013-08-28

    In collaboration with researchers at Vanderbilt University, North Carolina State University, Princeton and Oakridge National Laboratory we developed multiscale modeling and simulation methods capable of modeling the synthesis, assembly, and operation of molecular electronics devices. Our role in this project included the development of coarse-grained molecular and mesoscale models and simulation methods capable of simulating the assembly of millions of organic conducting molecules and other molecular components into nanowires, crossbars, and other organized patterns.

  6. EERE Success Story-California: Breakthrough in Algae Biology | Department

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of Energy Breakthrough in Algae Biology EERE Success Story-California: Breakthrough in Algae Biology January 31, 2014 - 12:00am Addthis Researchers at the Scripps Institution of Oceanography at University of California, San Diego, have made a significant breakthrough in algal biology with implications for biofuels. Algae typically overproduce lipid oils-energy-storing fat molecules used in biofuel production-when they are starved for nutrients, but this starvation also limits their growth

  7. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Dinner March 24, 2016 Hotel Shattuck Plaza AGENDA Reception 6:30 pm - 7:15 pm Dinner 7:15 pm Special Presentation 7:30 pm Representative Barbara Lee (D-CA) Panel Discussion 7:45 pm Moderated by Jeff Neaton Paul Alivisatos, Berkeley Lab/UC Berkeley Vikram Bajaj, Google[x] Life Sciences Ambika Bumb, Bikanta Steve Chu, Stanford University MEDIA Group Anniversary Highlights Video [VIDEO] Group Dinner

  8. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    D. Frank Ogletree Ogletree Staff Engineer, Imaging and Manipulation of Nanostructures dfogletree@lbl.gov 510.486.4862 Biography Education Postdoctoral Research Fellow with Miquel Salmeron developing ultra-high vacuum scanning tunneling microscopy in the Materials and Chemical Sciences Division, Lawrence Berkeley Laboratory, 1987 - 1988. Ph.D. in Experimental Solid State Physics, 1986, University of California, Berkeley, California. Thesis title: "Extending the Range of Low Energy Electron

  9. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Molecular Foundry User Policies and Definitions Download the complete User Policies and Definitions (PDF) Guiding principles Safety Costs 50/50 staff time model User proposal types Proposal questions and evaluation criteria Proposal Review Board (PRB) and review process User agreements with Berkeley Lab Access to other user facilities at LBNL Final project report Publications and acknowledgement User feedback and end-of-project survey Users' Executive Committee (UEC) Scientific Advisory Board

  10. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    and Dinner On March 24, 2016, the Molecular Foundry celebrated the 10th anniversary of the dedication of its iconic building with a full day scientific symposium and dinner event. This celebration recognized the Foundry's major scientific and operational milestones and looked forward to the promising future of nanoscience. Leaders from Congress, DOE, academia, industry, and Berkeley Lab joined prominent Foundry users and staff, both past and present, to participate in this celebration.

  11. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    One of the World's Premier Nanoscience Research Institutions Supported by the Department of Energy Office of Basic Energy Sciences (BES) through their Nanoscale Science Research Center (NSRC) program, the Molecular Foundry is a national User Facility for nanoscale science serving hundreds of academic, industrial and government scientists around the world each year. Users come to the Foundry to perform multidisciplinary research beyond the scope of an individual's own laboratory. By taking

  12. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Theory of Nanostructured Materials The Theory of Nanostructured Materials Facility at the Molecular Foundry is focused on expanding our understanding of materials at the nanoscale. Our research connects the structural and dynamical properties of materials to their functions, such as electrical conductivity and storage, light-harvesting for electricity and fuel, or gas separation and sequestration. We develop and employ a broad range of tools, including advanced electronic-structure theory,

  13. Molecular Foundry

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    POLICIES AND DEFINITIONS PROPOSAL GUIDE USER GUIDE USER PROGRAM SUBMIT A PROPOSAL » Reviewer Login » Proposal Deadline September 30, 2016 Instrument Scheduler Nanofabrication Instrument Scheduler User Program The Molecular Foundry user program gives researchers access to expertise and equipment for cutting-edge nanoscience in a collaborative, multidisciplinary environment. The program is open to scientists from academia, industry, and research institutes worldwide. These users join a vibrant

  14. Biology and Medicine Division: Annual report 1986

    SciTech Connect (OSTI)

    Not Available

    1987-04-01

    The Biology and Medicine Division continues to make important contributions in scientific areas in which it has a long-established leadership role. For 50 years the Division has pioneered in the application of radioisotopes and charged particles to biology and medicine. There is a growing emphasis on cellular and molecular applications in the work of all the Division's research groups. The powerful tools of genetic engineering, the use of recombinant products, the analytical application of DNA probes, and the use of restriction fragment length polymorphic DNA are described and proposed for increasing use in the future.

  15. Biological tracer method

    DOE Patents [OSTI]

    Strong-Gunderson, J.M.; Palumbo, A.V.

    1998-09-15

    The present invention is a biological tracer method for characterizing the movement of a material through a medium, comprising the steps of: introducing a biological tracer comprising a microorganism having ice nucleating activity into a medium; collecting at least one sample of the medium from a point removed from the introduction point; and analyzing the sample for the presence of the biological tracer. The present invention is also a method for using a biological tracer as a label for material identification by introducing a biological tracer having ice nucleating activity into a material, collecting a sample of a portion of the labelled material and analyzing the sample for the presence of the biological tracer. 2 figs.

  16. Biological tracer method

    DOE Patents [OSTI]

    Strong-Gunderson, Janet M. (Ten Mile, TN); Palumbo, Anthony V. (Oak Ridge, TN)

    1998-01-01

    The present invention is a biological tracer method for characterizing the movement of a material through a medium, comprising the steps of: introducing a biological tracer comprising a microorganism having ice nucleating activity into a medium; collecting at least one sample of the medium from a point removed from the introduction point; and analyzing the sample for the presence of the biological tracer. The present invention is also a method for using a biological tracer as a label for material identification by introducing a biological tracer having ice nucleating activity into a material, collecting a sample of a portion of the labelled material and analyzing the sample for the presence of the biological tracer.

  17. Genomics and Systems Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Genomics and Systems Biology Genomics and Systems Biology Los Alamos scientists perform research in functional genomics and structural genomics, and applications for such work cover diverse fields such as energy, agriculture, and environmental cleanup. Contact Us Babetta Marrone Biofuels Program Manager Email Cheryl Kuske DOE BER Biological System Science Division Program Manager Email Kirsten McCabe Emerging Threats Program Manager Email Rebecca McDonald Bioscience Communications Email "We

  18. Genomics and Systems Biology

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Genomics and Systems Biology LANL leads the world in computational finishing of microbial genomes Read caption + In 2013, Los Alamos scientist Richard Sayre and his team genetically modified the organisms to harvest light more efficiently for maximum production. Overview of Research and Highlights Researchers at Los Alamos National Laboratory are using their renowned expertise in genomics, computation, and experimental biology as the foundation of a dynamic systems biology capability. Systems

  19. Biological detector and method

    DOE Patents [OSTI]

    Sillerud, Laurel; Alam, Todd M.; McDowell, Andrew F.

    2015-11-24

    A biological detector includes a conduit for receiving a fluid containing one or more magnetic nanoparticle-labeled, biological objects to be detected and one or more permanent magnets or electromagnet for establishing a low magnetic field in which the conduit is disposed. A microcoil is disposed proximate the conduit for energization at a frequency that permits detection by NMR spectroscopy of whether the one or more magnetically-labeled biological objects is/are present in the fluid.

  20. Biological detector and method

    DOE Patents [OSTI]

    Sillerud, Laurel; Alam, Todd M; McDowell, Andrew F

    2013-02-26

    A biological detector includes a conduit for receiving a fluid containing one or more magnetic nanoparticle-labeled, biological objects to be detected and one or more permanent magnets or electromagnet for establishing a low magnetic field in which the conduit is disposed. A microcoil is disposed proximate the conduit for energization at a frequency that permits detection by NMR spectroscopy of whether the one or more magnetically-labeled biological objects is/are present in the fluid.

  1. Biological detector and method

    DOE Patents [OSTI]

    Sillerud, Laurel; Alam, Todd M; McDowell, Andrew F

    2014-04-15

    A biological detector includes a conduit for receiving a fluid containing one or more magnetic nanoparticle-labeled, biological objects to be detected and one or more permanent magnets or electromagnet for establishing a low magnetic field in which the conduit is disposed. A microcoil is disposed proximate the conduit for energization at a frequency that permits detection by NMR spectroscopy of whether the one or more magnetically-labeled biological objects is/are present in the fluid.

  2. Yuan T. Lee and Molecular Beam Studies

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Yuan T. Lee and Molecular Beam Studies Resources with Additional Information * Awards Yuan T. Lee Courtesy of the Michigan State University Chemistry Department Yuan Tseh Lee 'received the 1986 Nobel Prize in Chemistry, ... for elucidating the collision dynamics of elementary chemical reactions. During a postdoctoral appointment at Harvard with [Dudley R.] Herschbach, Lee designed and built a technologically advanced "universal" machine with electron bombardment ionizer and mass

  3. The Intersection of Physics and Biology

    ScienceCinema (OSTI)

    Liphardt, Jan [University of California, Berkeley, California, United States

    2010-09-01

    In April 1953, Watson and Crick largely defined the program of 20th century biology: obtaining the blueprint of life encoded in the DNA. Fifty years later, in 2003, the sequencing of the human genome was completed. Like any major scientific breakthrough, the sequencing of the human genome raised many more questions than it answered. I'll brief you on some of the big open problems in cell and developmental biology, and I'll explain why approaches, tools, and ideas from the physical sciences are currently reshaping biological research. Super-resolution light microscopies are revealing the intricate spatial organization of cells, single-molecule methods show how molecular machines function, and new probes are clarifying the role of mechanical forces in cell and tissue function. At the same time, Physics stands to gain beautiful new problems in soft condensed matter, quantum mechanics, and non-equilibrium thermodynamics.

  4. Integrated Biological Control

    SciTech Connect (OSTI)

    JOHNSON, A.R.

    2002-09-01

    Biological control is any activity taken to prevent, limit, clean up, or remediate potential environmental, health and safety, or workplace quality impacts from plants, animals, or microorganisms. At Hanford the principal emphasis of biological control is to prevent the transport of radioactive contamination by biological vectors (plants, animals, or microorganisms), and where necessary, control and clean up resulting contamination. Other aspects of biological control at Hanford include industrial weed control (e.g.; tumbleweeds), noxious weed control (invasive, non-native plant species), and pest control (undesirable animals such as rodents and stinging insects; and microorganisms such as molds that adversely affect the quality of the workplace environment). Biological control activities may be either preventive (apriori) or in response to existing contamination spread (aposteriori). Surveillance activities, including ground, vegetation, flying insect, and other surveys, and apriori control actions, such as herbicide spraying and placing biological barriers, are important in preventing radioactive contamination spread. If surveillance discovers that biological vectors have spread radioactive contamination, aposteriori control measures, such as fixing contamination, followed by cleanup and removal of the contamination to an approved disposal location are typical response functions. In some cases remediation following the contamination cleanup and removal is necessary. Biological control activities for industrial weeds, noxious weeds and pests have similar modes of prevention and response.

  5. Integrated Biological Control

    SciTech Connect (OSTI)

    JOHNSON, A.R.

    2003-10-09

    Biological control is any activity taken to prevent, limit, clean up, or remediate potential environmental, health and safety, or workplace quality impacts from plants, animals, or microorganisms. At Hanford the principal emphasis of biological control is to prevent the transport of radioactive contamination by biological vectors (plants, animals, or microorganisms), and where necessary, control and clean up resulting contamination. Other aspects of biological control at Hanford include industrial weed control (e.g.; tumbleweeds), noxious weed control (invasive, non-native plant species), and pest control (undesirable animals such as rodents and stinging insects, and microorganisms such as molds that adversely affect the quality of the workplace environment). Biological control activities may be either preventive (a priori) or in response to existing contamination spread (a posteriori). Surveillance activities, including ground, vegetation, flying insect, and other surveys, and a priori control actions, such as herbicide spraying and placing biological barriers, are important in preventing radioactive contamination spread. If surveillance discovers that biological vectors have spread radioactive contamination, a posteriori control measures, such as fixing contamination, followed by cleanup and removal of the contamination to an approved disposal location are typical response functions. In some cases remediation following the contamination cleanup and removal is necessary. Biological control activities for industrial weeds, noxious weeds and pests have similar modes of prevention and response.

  6. University of Nebraska-Lincoln and University of Florida (Building...

    Open Energy Info (EERE)

    Nebraska-Lincoln and University of Florida (Building Energy Efficient Homes for America) Jump to: navigation, search Name: University of Nebraska-Lincoln and University of Florida...

  7. Biological sample collector

    DOE Patents [OSTI]

    Murphy, Gloria A.

    2010-09-07

    A biological sample collector is adapted to a collect several biological samples in a plurality of filter wells. A biological sample collector may comprise a manifold plate for mounting a filter plate thereon, the filter plate having a plurality of filter wells therein; a hollow slider for engaging and positioning a tube that slides therethrough; and a slide case within which the hollow slider travels to allow the tube to be aligned with a selected filter well of the plurality of filter wells, wherein when the tube is aligned with the selected filter well, the tube is pushed through the hollow slider and into the selected filter well to sealingly engage the selected filter well and to allow the tube to deposit a biological sample onto a filter in the bottom of the selected filter well. The biological sample collector may be portable.

  8. Lancaster University | Open Energy Information

    Open Energy Info (EERE)

    University Jump to: navigation, search Name: Lancaster University Address: Engineering Department Lancaster University Place: Lancaster Zip: LA1 4YR Region: United Kingdom Sector:...

  9. Napier University | Open Energy Information

    Open Energy Info (EERE)

    University Jump to: navigation, search Name: Napier University Place: Edinburgh, Scotland, United Kingdom Zip: EH14 1DJ Product: A university located in Edinburgh, Scotland that...

  10. Hamdard University | Open Energy Information

    Open Energy Info (EERE)

    Hamdard University Jump to: navigation, search Name: Hamdard University Place: Karachi, Pakistan Zip: 74600 Sector: Solar Product: University setting up Pakistan's first solar lab....

  11. Purdue University | Open Energy Information

    Open Energy Info (EERE)

    Purdue University Jump to: navigation, search Logo: Purdue University Name: Purdue University Address: West Lafayette, IN Zip: 47907 Phone Number: (765) 494-4600 Website:...

  12. Biological and Chemical Security

    SciTech Connect (OSTI)

    Fitch, P J

    2002-12-19

    The LLNL Chemical & Biological National Security Program (CBNP) provides science, technology and integrated systems for chemical and biological security. Our approach is to develop and field advanced strategies that dramatically improve the nation's capabilities to prevent, prepare for, detect, and respond to terrorist use of chemical or biological weapons. Recent events show the importance of civilian defense against terrorism. The 1995 nerve gas attack in Tokyo's subway served to catalyze and focus the early LLNL program on civilian counter terrorism. In the same year, LLNL began CBNP using Laboratory-Directed R&D investments and a focus on biodetection. The Nunn-Lugar-Domenici Defense Against Weapons of Mass Destruction Act, passed in 1996, initiated a number of U.S. nonproliferation and counter-terrorism programs including the DOE (now NNSA) Chemical and Biological Nonproliferation Program (also known as CBNP). In 2002, the Department of Homeland Security was formed. The NNSA CBNP and many of the LLNL CBNP activities are being transferred as the new Department becomes operational. LLNL has a long history in national security including nonproliferation of weapons of mass destruction. In biology, LLNL had a key role in starting and implementing the Human Genome Project and, more recently, the Microbial Genome Program. LLNL has over 1,000 scientists and engineers with relevant expertise in biology, chemistry, decontamination, instrumentation, microtechnologies, atmospheric modeling, and field experimentation. Over 150 LLNL scientists and engineers work full time on chemical and biological national security projects.

  13. Work with Biological Materials

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Work with Biological Materials Print Planning A complete Experiment Safety Sheet (ESS) is required before work can be done at the ALS. This ESS is either a part of the proposal process or may be completed as an independent document. In the ESS, identify each material (including all biological materials) with which you will be working. The regulatory oversight for biological work is very complicated and we need to understand the risk levels involved with the material you plan to use at the ALS,

  14. Work with Biological Materials

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Work with Biological Materials Print Planning A complete Experiment Safety Sheet (ESS) is required before work can be done at the ALS. This ESS is either a part of the proposal process or may be completed as an independent document. In the ESS, identify each material (including all biological materials) with which you will be working. The regulatory oversight for biological work is very complicated and we need to understand the risk levels involved with the material you plan to use at the ALS,

  15. Work with Biological Materials

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Work with Biological Materials Print Planning A complete Experiment Safety Sheet (ESS) is required before work can be done at the ALS. This ESS is either a part of the proposal process or may be completed as an independent document. In the ESS, identify each material (including all biological materials) with which you will be working. The regulatory oversight for biological work is very complicated and we need to understand the risk levels involved with the material you plan to use at the ALS,

  16. Institute for Molecular Medicine Research Program

    SciTech Connect (OSTI)

    Phelps, Michael E

    2012-12-14

    The objectives of the project are the development of new Positron Emission Tomography (PET) imaging instrumentation, chemistry technology platforms and new molecular imaging probes to examine the transformations from normal cellular and biological processes to those of disease in pre-clinical animal models. These technology platforms and imaging probes provide the means to: 1. Study the biology of disease using pre-clinical mouse models and cells. 2. Develop molecular imaging probes for imaging assays of proteins in pre-clinical models. 3. Develop imaging assays in pre-clinical models to provide to other scientists the means to guide and improve the processes for discovering new drugs. 4. Develop imaging assays in pre-clinical models for others to use in judging the impact of drugs on the biology of disease.

  17. Excitonic Quantum Random Walk in Biological Phycocyanin Nanowires |

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    MIT-Harvard Center for Excitonics Quantum Random Walk in Biological Phycocyanin Nanowires October 6, 2015 at 4:30pm/ 36-428 Yossi Paltiel Department of Applied Physics, The Hebrew University of Jerusalem yossi-3a The importance of quantum processes in biology is starting to be recognized. Quantum processes are being discussed in the context of enzyme function, olfaction, magnetic sensing and most prominently in photosynthetic light-harvesting complexes. These findings suggest that a key to

  18. Environmental Impacts of Wind Power Development on the Population Biology

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    of Greater Prairie-Chickens | Department of Energy Environmental Impacts of Wind Power Development on the Population Biology of Greater Prairie-Chickens Environmental Impacts of Wind Power Development on the Population Biology of Greater Prairie-Chickens This report summarizes the results of a seven-year, DOE-funded research project, conducted by researchers from Kansas State University and the National Wind Coordinating Collaborative, to assess the effects of wind energy development in

  19. Computational Biology: A Recipe for Ligand-Binding Proteins

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Computational Biology: A Recipe for Ligand-Binding Proteins Authors: Ghirlanda, G. Title: Computational Biology: A Recipe for Ligand-Binding Proteins Source: Nature Year: 2013 Volume: 501 Pages: 177-178 ABSTRACT: Cellular cross-talk, enzymatic catalysis and regulation of gene expression all depend on molecular recognition. A method that allows the design of proteins with desired recognition sites could thus be revolutionary Date of online publication: Thu, 2013-09-12 Link online:

  20. Duke University and Duke University Medical Center

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Duke University and Duke University Medical Center Date Revised: 3/5/97; 4/25/01 PERSONNEL DOSIMETER REQUEST AND RADIATION EXPOSURE HISTORY 1. Name (Please print - Last name, First name, MI) 2. Duke Unique ID 3. Date of Birth 4. Age (in full years) 5. Gender (circle one) Male Female 6. WORK Telephone No. 7. Name of Department AND Authorized User X-rays Specify type of equipment: 8. Type of radiation to be monitored Radioactive Materials Specify radioisotopes: Other Specify: 9. Have you been

  1. Biological and Environmental Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biological Science Biological Science The protozoan Plasmodium falciparum gliding through a cell in the gut of a mosquito, its primary host. Although five different species of Plasmodium can cause malaria, Plasmodium falciparum causes the most severe disease. | Photo courtesy of Wikipedia Commons. <a href="http://energy.gov/articles/malaria-researchers-find-weakness-global-killer">Read more</a> The protozoan Plasmodium falciparum gliding through a cell in the gut of a

  2. Biological and Environmental Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biological and Environmental Research Biological and Environmental Research Understanding how genomic information is translated to functional capabilities, and the roles of Earth's biogeochemical systems so we can predict climate decades or centuries into the future. Get Expertise Cheryl Kuske (505) 665-4800 Email James Bossert (505) 667-3644 Email Manvendra Dubey (505) 665-3128 Email Kim Nitschke (505) 667-1186 Email Phil Jones (505) 667-6387 Email Cathy Wilson (505) 667-0202 Email Conducting

  3. Nuclear Energy University Programs

    Broader source: Energy.gov (indexed) [DOE]

    * Awards that are experimental - 30 * Awards in materials and waste - 30 * Awards to Nuclear Engineering Faculty - 18 * Number of universities receiving awards - 26 * Number of...

  4. Fermilab Today | University Profiles

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    University Profiles Archive Subscribe | Contact Fermilab Today | Archive | Classifieds Search GO More than 2,000 scientists worldwide work with Fermilab. In the United States,...

  5. University Research Summaries

    Broader source: Energy.gov [DOE]

    The Idaho National Laboratory published the U.S. Department of Energy's (DOE) Geothermal Technologies Office 2001 University Research Summaries. 

  6. university of california

    National Nuclear Security Administration (NNSA)

    Led by University of California, Berkeley Awarded 25M NNSA Grant for Nuclear Science and Security Research http:nnsa.energy.govmediaroompressreleases...

  7. PNNL: Center for Molecular Electrocatalysis - Energy Frontier Research

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Center - Related Links Related Links Center for Molecular Electrocatalysis Members Pacific Northwest National Laboratory University of Illinois Yale University U.S. Department of Energy U.S. Department of Energy Office of Science Basic Energy Sciences Energy Frontier Research Centers

  8. Biological Effects of Ionizing Radiation

    DOE R&D Accomplishments [OSTI]

    Ingram, M.; Mason, W. B.; Whipple, G. H.; Howland, J. W.

    1952-04-07

    This report presents a review of present knowledge and concepts of the biological effects of ionizing radiations. Among the topics discussed are the physical and chemical effects of ionizing radiation on biological systems, morphological and physiological changes observed in biological systems subjected to ionizing radiations, physiological changes in the intact animal, latent changes following exposure of biological systems to ionizing radiations, factors influencing the biological response to ionizing radiation, relative effects of various ionizing radiations, and biological dosimetry.

  9. Green Biologics | Open Energy Information

    Open Energy Info (EERE)

    Biologics Jump to: navigation, search Name: Green Biologics Place: Oxfordshire, United Kingdom Sector: Biomass, Renewable Energy Product: Oxfordshire-based industrial biotech...

  10. Modeling the Molecular Basis of Parkinson's Disease | Argonne Leadership

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Computing Facility Alpha-synuclein pentamer constructed with 4ns molecular dynamics (MD) conformers after equilibration on the membrane with MD. Alpha-synuclein pentamer constructed with 4ns molecular dynamics (MD) conformers after equilibration on the membrane with MD. Modeling the Molecular Basis of Parkinson's Disease PI Name: Igor Tsigelny PI Email: itsigeln@ucsd.edu Institution: University of California-San Diego/SDSC Allocation Program: INCITE Allocation Hours at ALCF: 1.2 Million

  11. Report of the Structural Biology Subcommittee of the Biological...

    Office of Science (SC) Website

    ... David Kingsbury (absent from meeting) Chiron Corporation Emeryville, California Dr. Anthony Kossiakoff University of Chicago Chicago, Illinois Dr. Janet Smith Purdue University ...

  12. Biological applications of ultraviolet free-electron lasers

    SciTech Connect (OSTI)

    Sutherland, J.C.

    1997-10-01

    This review examines the possibilities for biological research using the three ultraviolet free-electron lasers that are nearing operational status in the US. The projected operating characteristics of major interest in biological research of the free-electron lasers at Brookhaven National Laboratory, the Thomas Jefferson National Accelerator Facility, and Duke University are presented. Experimental applications in the areas of far- and vacuum ultraviolet photophysics and photochemistry, structural biology, environmental photobiology, and medical research are discussed and the prospects for advances in these areas, based upon the characteristics of the new ultraviolet free-electron lasers, are evaluated.

  13. Final Report - Montana State University - Microbial Activity and

    Office of Scientific and Technical Information (OSTI)

    Precipitation at Solution-Solution Mixing Zones in Porous Media (Technical Report) | SciTech Connect Final Report - Montana State University - Microbial Activity and Precipitation at Solution-Solution Mixing Zones in Porous Media Citation Details In-Document Search Title: Final Report - Montana State University - Microbial Activity and Precipitation at Solution-Solution Mixing Zones in Porous Media Background. The use of biological and chemical processes that degrade or immobilize

  14. CMI Education Partner: Rutgers, The State University of New Jersey |

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Critical Materials Institute Rutgers, The State University of New Jersey Rutgers, the state university of New Jersey, offers courses in several areas: Materials Science and Engineering, undergraduate level MSE Energy Conversion and Storage Chemical and Biological Engineering Geology-related courses in School of Science and Art Materials Science and Engineering curriculum Online list can be found at http://mse.rutgers.edu/undergraduate-courses

  15. 7th Annual Systems Biology Symposium: Systems Biology and Engineering

    SciTech Connect (OSTI)

    Galitski, Timothy P.

    2008-04-01

    Systems biology recognizes the complex multi-scale organization of biological systems, from molecules to ecosystems. The International Symposium on Systems Biology has been hosted by the Institute for Systems Biology in Seattle, Washington, since 2002. The annual two-day event gathers the most influential researchers transforming biology into an integrative discipline investingating complex systems. Engineering and application of new technology is a central element of systems biology. Genome-scale, or very small-scale, biological questions drive the enigneering of new technologies, which enable new modes of experimentation and computational analysis, leading to new biological insights and questions. Concepts and analytical methods in engineering are now finding direct applications in biology. Therefore, the 2008 Symposium, funded in partnership with the Department of Energy, featured global leaders in "Systems Biology and Engineering."

  16. Biological effectiveness of neutrons: Research needs

    SciTech Connect (OSTI)

    Casarett, G.W.; Braby, L.A.; Broerse, J.J.; Elkind, M.M.; Goodhead, D.T.; Oleinick, N.L.

    1994-02-01

    The goal of this report was to provide a conceptual plan for a research program that would provide a basis for determining more precisely the biological effectiveness of neutron radiation with emphasis on endpoints relevant to the protection of human health. This report presents the findings of the experts for seven particular categories of scientific information on neutron biological effectiveness. Chapter 2 examines the radiobiological mechanisms underlying the assumptions used to estimate human risk from neutrons and other radiations. Chapter 3 discusses the qualitative and quantitative models used to organize and evaluate experimental observations and to provide extrapolations where direct observations cannot be made. Chapter 4 discusses the physical principles governing the interaction of radiation with biological systems and the importance of accurate dosimetry in evaluating radiation risk and reducing the uncertainty in the biological data. Chapter 5 deals with the chemical and molecular changes underlying cellular responses and the LET dependence of these changes. Chapter 6, in turn, discusses those cellular and genetic changes which lead to mutation or neoplastic transformation. Chapters 7 and 8 examine deterministic and stochastic effects, respectively, and the data required for the prediction of such effects at different organizational levels and for the extrapolation from experimental results in animals to risks for man. Gaps and uncertainties in this data are examined relative to data required for establishing radiation protection standards for neutrons and procedures for the effective and safe use of neutron and other high-LET radiation therapy.

  17. Bagley University Classroom Building

    High Performance Buildings Database

    Duluth, MN, MN LEED PLATINUM CERTIFIED AND PASSIVHAUS ( certification pending) CLASSROOM BUILDING The Nature Preserve where this building is located is a contiguous natural area, 55 acres in size, deeded to the University in the 1950's for educational and recreational use. The site has hiking trails through old growth hard woods frequented by the university students as well as the public. We were charged with designing a facility to serve eight different departments for the nature portions of their teaching and study at a regional University.

  18. Biological response modifiers

    SciTech Connect (OSTI)

    Weller, R.E.

    1991-10-01

    Much of what used to be called immunotherapy is now included in the term biological response modifiers. Biological response modifiers (BRMs) are defined as those agents or approaches that modify the relationship between the tumor and host by modifying the host's biological response to tumor cells with resultant therapeutic effects.'' Most of the early work with BRMs centered around observations of spontaneous tumor regression and the association of tumor regression with concurrent bacterial infections. The BRM can modify the host response in the following ways: Increase the host's antitumor responses through augmentation and/or restoration of effector mechanisms or mediators of the host's defense or decrease the deleterious component by the host's reaction; Increase the host's defenses by the administration of natural biologics (or the synthetic derivatives thereof) as effectors or mediators of an antitumor response; Augment the host's response to modified tumor cells or vaccines, which might stimulate a greater response by the host or increase tumor-cell sensitivity to an existing response; Decrease the transformation and/or increase differentiation (maturation) of tumor cells; or Increase the ability of the host to tolerate damage by cytotoxic modalities of cancer treatment.

  19. NEUP Approved Universities

    Broader source: Energy.gov [DOE]

    U.S. universities and colleges must apply to the U.S. Department of Energy to administer NEUP scholarships and fellowships.  That is done through a separate solicitation operated by the Department...

  20. Program in Functional Genomics of Autoimmunity and Immunology of yhe University of Kentucky and the University of Alabama

    SciTech Connect (OSTI)

    Alan M Kaplan

    2012-10-12

    This grant will be used to augment the equipment infrastructure and core support at the University of Kentucky and the University of Alabama particularly in the areas of genomics/informatics, molecular analysis and cell separation. In addition, we will promote collaborative research interactions through scientific workshops and exchange of scientists, as well as joint exploration of the role of immune receptors as targets in autoimmunity and host defense, innate and adaptive immune responses, and mucosal immunity in host defense.

  1. Oak Ridge Associated Universities

    Office of Legacy Management (LM)

    Facility and Site Decommissioning U.S. Department of Energy ORAU 89lA-42 VERIFICATION OF REMEDIAL ACTION ON VENTILATION SYSTEMS JONES CHEMICAL LABORATORY UNIVERSITY OF CHICAGO CHICAGO, ILLINOIS M. R. LANDIS Radiological Site Assessment Program Manpower Education, Research, and Training Division FINAL REPORT JANUARY 1989 ORAU 89IA-42 3 VERIFICATION OF REMEDIAL ACTION ON VENTILATION SYSTEMS JONES CHEMICAL LABORATORY UNIVERSITY OF CHICAGO CHICAGO, ILLINOIS Prepared by M.R. Landis Radiological Site

  2. The Runaway Universe

    SciTech Connect (OSTI)

    Blanford, Roger

    2004-10-26

    The Universe appears to be flat, accelerating and lightweight. In this talk, I will explain what these terms mean, how we developed this view and its implications. I will also discuss the connection between cosmology and particle physics experiments being conducted at accelerators and in underground laboratories. I will conclude with a description of some proposed telescopes that will help us understand much more about the geometry, expansion and contents of our Universe.

  3. College / University Programs - SRSCRO

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    header-college College/University Programs Colleges and universities in the SRSCRO region offer a variety of educational opportunities that prepare students for careers in the nuclear industry. Programs are designed for students choosing to start a career for the first time and those seeking to enhance or change careers. Aiken Technical College Certificate and associate degree opportunities are available for students interested in pursuing a career in the nuclear industry, including nuclear

  4. Healthcare Energy: State University of New York Upstate Medical University

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    East Wing | Department of Energy State University of New York Upstate Medical University East Wing Healthcare Energy: State University of New York Upstate Medical University East Wing The Building Technologies Office conducted a healthcare energy end-use monitoring project in partnership with two hospitals. This page contains highlights from monitoring at the East Wing, a hospital building addition at the State University of New York Upstate Medical University. In the figure above, click on

  5. University contracts summary book

    SciTech Connect (OSTI)

    1980-08-01

    The principal objectives of the Fossil Energy Program are to seek new ideas, new data, fundamental knowledge that will support the ongoing programs, and new processes to better utilize the nation's fossil energy resources with greater efficiency and environmental acceptability. Toward this end, the Department of Energy supports research projects conducted by universities and colleges to: Ensure a foundation for innovative technology through the use of the capabilities and talents in our academic institutions; provide an effective, two-way channel of communication between the Department of Energy and the academic community; and ensure that trained technical manpower is developed to carry out basic and applied research in support of DOE's mission. Fossil Energy's university activities emphasize the type of research that universities can do best - research to explore the potential of novel process concepts, develop innovative methods and materials for improving existing processes, and obtain fundamental information on the structure of coal and mechanisms of reactions of coal, shale oil, and other fossil energy sources. University programs are managed by different Fossil Energy technical groups; the individual projects are described in greater detail in this book. It is clear that a number of research areas related to the DOE Fossil Energy Program have been appropriate for university involvement, and that, with support from DOE, university scientific and technical expertise can be expected to continue to play a significant role in the advancement of fossil energy technology in the years to come.

  6. University) [Johns Hopkins University] 71 CLASSICAL AND QUANTUM...

    Office of Scientific and Technical Information (OSTI)

    Zlatko (Johns Hopkins University) Johns Hopkins University 71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS; 75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND SUPERFLUIDITY;...

  7. Biological particle identification apparatus

    DOE Patents [OSTI]

    Salzman, Gary C.; Gregg, Charles T.; Grace, W. Kevin; Hiebert, Richard D.

    1989-01-01

    An apparatus and method for making multiparameter light scattering measurements from suspensions of biological particles is described. Fourteen of the sixteen Mueller matrix elements describing the particles under investigation can be substantially individually determined as a function of scattering angle and probing radiations wavelength, eight elements simultaneously for each of two apparatus configurations using an apparatus which incluees, in its simplest form, two polarization modulators each operating at a chosen frequency, one polarizer, a source of monochromatic electromagnetic radiation, a detector sensitive to the wavelength of radiation employed, eight phase-sensitive detectors, and appropriate electronics. A database of known biological particle suspensions can be assembled, and unknown samples can be quickly identified once measurements are performed on it according to the teachings of the subject invention, and a comparison is made with the database.

  8. BIOLOGICAL IRRADIATION FACILITY

    DOE Patents [OSTI]

    McCorkle, W.H.; Cern, H.S.

    1962-04-24

    A facility for irradiating biological specimens with neutrons is described. It includes a reactor wherein the core is off center in a reflector. A high-exposure room is located outside the reactor on the side nearest the core while a low-exposure room is located on the opposite side. Means for converting thermal neutrons to fast neutrons are movably disposed between the reactor core and the high and low-exposure rooms. (AEC)

  9. Murdoch University | Open Energy Information

    Open Energy Info (EERE)

    offers a university education of the highest quality and has been ranked the best teaching campus of all Australia's public universities in an independent national survey of...

  10. Universally oriented renewable liquid mirror

    DOE Patents [OSTI]

    Ryutov, Dmitri D.; Toor, Arthur

    2004-07-20

    A universally oriented liquid mirror. A liquid and a penetrable unit are operatively connected to provide a mirror that can be universally oriented.

  11. Sichuan University | Open Energy Information

    Open Energy Info (EERE)

    Sichuan University Place: Chengdu, Sichuan Province, China Zip: 610065 Product: A comprehensive university in south-west China. Coordinates: 30.67, 104.071022 Show Map Loading...

  12. Uppsala University | Open Energy Information

    Open Energy Info (EERE)

    University Jump to: navigation, search Name: Uppsala University Address: Box 534 Place: Uppsala Zip: 75121 Region: Sweden Sector: Marine and Hydrokinetic Phone Number:...

  13. Split University | Open Energy Information

    Open Energy Info (EERE)

    Name: Split University Place: Zagreb, Croatia Sector: Hydro, Solar Product: Croatia-based electrical engineering faculty of Split University. Involved in developing small hydro and...

  14. Universal Energy | Open Energy Information

    Open Energy Info (EERE)

    Energy Jump to: navigation, search Name: Universal Energy Place: Nanjing, Jiangsu Province, China Sector: Solar Product: Universal Energy is a PV module and solar hot water systems...

  15. Fermilab Today | Brown University Profile

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Brown University April 29, 2010 NAME: Brown University HOME TOWN: Providence, Rhode Island MASCOT: Bruno the Bear SCHOOL COLORS: Seal brown and cardinal red PARTICLE PHYSICS...

  16. Fermilab Today | Kansas State University

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Kansas State University Feb. 27, 2013 NAME: Kansas State University HOME TOWN: Manhattan, Kan. MASCOT: Willie the Wildcat COLORS: Royal purple COLLABORATING AT FERMILAB SINCE: 1993...

  17. Fermilab Today | Purdue University Calumet

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    University Calumet Jan. 9, 2013 NAME: Purdue University Calumet HOME TOWN: Hammond, Ind. MASCOT: Peregrine COLORS: Black and gold COLLABORATING AT FERMILAB SINCE: 2005 WORLDWIDE...

  18. Fermilab Today | Wayne State University

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Wayne State University May 29, 2013 NAME: Wayne State University HOME TOWN: Detroit, Mich. COLORS: Green and gold COLLABORATING AT FERMILAB SINCE: 1995 WORLDWIDE PARTICLE PHYSICS...

  19. Report of The Structural Biology Subcommittee of The Biological and

    Office of Science (SC) Website

    Environmental Research Advisory Committee | U.S. DOE Office of Science (SC) Report of The Structural Biology Subcommittee of The Biological and Environmental Research Advisory Committee Biological and Environmental Research Advisory Committee (BERAC) BERAC Home Meetings Members Charges/Reports Current BERAC Charges Archive of BERAC Reports Charter .pdf file (135KB) BER Committees of Visitors Federal Advisory Committees BER Home Charges/Reports Report of The Structural Biology Subcommittee of

  20. Multiscale reactive molecular dynamics | Argonne Leadership Computing

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Facility reactive molecular dynamics Authors: Chris KnighT, Gerrick E. Lindberg, Gregory A. Voth Many processes important to chemistry, materials science, and biology cannot be described without considering electronic and nuclear-level dynamics and their coupling to slower, cooperative motions of the system. These inherently multiscale problems require computationally efficient and accurate methods to converge statistical properties. In this paper, a method is presented that uses data

  1. Music of the Universe

    SciTech Connect (OSTI)

    2010-01-01

    Scientists are quite familiar with what a supernova looks like when these stars are destroyed in the most massive explosions in the universe, they leave their mark as one of the brightest objects in space, at least for several weeks. While the supernova can be seen, it cant be heard, as sound waves cannot travel through space. But what if the light waves emitted by the exploding star and other cosmological phenomena could be translated into sound? Thats the idea behind a Rhythms of the Universe, a musical project to sonify the universe by Grateful Dead percussionist and Grammy award-winning artist Mickey Hart that caught the attention of Nobel Prize-winning astrophysicist George Smoot of Lawrence Berkeley National Laboratory. Sounds courtesy of Keith Jackson. Images courtesy of NASA

  2. Arms Control: US and International efforts to ban biological weapons

    SciTech Connect (OSTI)

    Not Available

    1992-12-01

    The Bacteriological (Biological) and Toxin Weapons Convention, the treaty that bans the development, production, and stockpiling and acquisition of biological weapons was opened for signature in 1972 and came into force in 1975 after being ratified by 22 governments, including the depository nations of the USA, the United Kingdom, and the former Soviet Union. In support of the Convention, the USA later established export controls on items used to make biological weapons. Further, in accordance with the 1990 President`s Enhanced Proliferation Control Initiative, actions were taken to redefine and expand US export controls, as well as to encourage multilateral controls through the Australia Group. Thus far, the Convention has not been effective in stopping the development of biological weapons. The principal findings as to the reasons of the failures of the Convention are found to be: the Convention lacks universality, compliance measures are effective, advantage of verification may outweigh disadvantages. Recommendations for mitigating these failures are outlined in this report.

  3. Abengoa Mojave Final Biological Opinion

    Broader source: Energy.gov [DOE]

    Biological Opinion on Mojave Solar, LLC's Mojave Solar Project, San Bernardino County, California (8-8-11-F-3)

  4. Oregon State University | Open Energy Information

    Open Energy Info (EERE)

    University Jump to: navigation, search Logo: Oregon State University Name: Oregon State University Address: Oregon State University Corvallis, OR Zip: 97331-4501 Year Founded: 1868...

  5. Pennsylvania State University | Open Energy Information

    Open Energy Info (EERE)

    University Jump to: navigation, search Logo: Pennsylvania State University Name: Pennsylvania State University Address: 201 Shields Building University Park, PA 16802 Zip: 16802...

  6. Molecular Science Research Center 1992 annual report

    SciTech Connect (OSTI)

    Knotek, M.L.

    1994-01-01

    The Molecular Science Research Center is a designated national user facility, available to scientists from universities, industry, and other national laboratories. After an opening section, which includes conferences hosted, appointments, and projects, this document presents progress in the following fields: chemical structure and dynamics; environmental dynamics and simulation; macromolecular structure and dynamics; materials and interfaces; theory, modeling, and simulation; and computing and information sciences. Appendices are included: MSRC staff and associates, 1992 publications and presentations, activities, and acronyms and abbreviations.

  7. Elements in biological AMS

    SciTech Connect (OSTI)

    Vogel, J.S.; McAninch, J.; Freeman, S.

    1996-08-01

    AMS (Accelerator Mass Spectrometry) provides high detection sensitivity for isotopes whose half-lives are between 10 years and 100 million years. {sup 14}C is the most developed of such isotopes and is used in tracing natural and anthropogenic organic compounds in the Earth`s biosphere. Thirty-three elements in the main periodic table and 17 lanthanides or actinides have long lived isotopes, providing potential tracers for research in elemental biochemistry. Overlap of biologically interesting heavy elements and possible AMS tracers is discussed.

  8. Method and apparatus for the gas phase decontamination of chemical and biological agents

    DOE Patents [OSTI]

    O'Neill, Hugh J.; Brubaker, Kenneth L.

    2003-10-07

    An apparatus and method for decontaminating chemical and biological agents using the reactive properties of both the single atomic oxygen and the hydroxyl radical for the decontamination of chemical and biological agents. The apparatus is self contained and portable and allows for the application of gas reactants directly at the required decontamination point. The system provides for the use of ultraviolet light of a specific spectral range to photolytically break down ozone into molecular oxygen and hydroxyl radicals where some of the molecular oxygen is in the first excited state. The excited molecular oxygen will combine with water vapor to produce two hydroxyl radicals.

  9. Universal nonlinear entanglement witnesses

    SciTech Connect (OSTI)

    Kotowski, Marcin; Kotowski, Michal [College of Inter-Faculty Individual Studies in Mathematics and Natural Sciences, Warsaw University, PL-Warszawa (Poland); Center for Theoretical Physics, Polish Academy of Sciences, Aleja Lotnikow 32/44, PL-02-668 Warszawa (Poland); Kus, Marek [Center for Theoretical Physics, Polish Academy of Sciences, Aleja Lotnikow 32/44, PL-02-668 Warszawa (Poland)

    2010-06-15

    We give a universal recipe for constructing nonlinear entanglement witnesses able to detect nonclassical correlations in arbitrary systems of distinguishable and/or identical particles for an arbitrary number of constituents. The constructed witnesses are expressed in terms of expectation values of observables. As such, they are, at least in principle, measurable in experiments.

  10. Cleantech University Prize

    Broader source: Energy.gov [DOE]

    The U.S. Department of Energy’s (DOE’s) Cleantech University Prize (Cleantech UP) aims to inspire the next generation of clean energy entrepreneurs and innovators by providing them with competitive funding for business development and commercialization training and other educational opportunities.

  11. PROJECT PROFILE: Boston University

    Office of Energy Efficiency and Renewable Energy (EERE)

    The Boston University project under CSP: Apollo will use laboratory-scale electrodynamic-screen self-cleaning solar technology with heliostat mirrors and parabolic troughs in large scale solar plants. The objective is to reduce both the need to clean mirrors with water and the degradation of CSP collector performance due to deposited dust.

  12. CASL - University of Michigan

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    University of Michigan Ann Arbor, MI The U-M College of Engineering is home to four leading engineering departments that are actively participating in CASL: Nuclear Engineering and Radiological Sciences Aerospace Engineering Materials Science and Engineering Mechanical Engineering Key Contributions Computational methods development for radiation transport and coupled multiphysics simulation Uncertainty quantification for computational fluid dynamics with adjoint methods Analysis of structural

  13. Computational methods for molecular docking

    SciTech Connect (OSTI)

    Klebe, G.; Lengauer, T.

    1995-12-31

    This tutorial was one of eight tutorials selected to be presented at the Third International Conference on Intelligent Systems for Molecular Biology which was held in the United Kingdom from July 16 to 19, 1995. Recently, it has been demonstrated that the knowledge of the three-dimensional structure of the protein can be used to derive new protein ligands with improved binding properties. This tutorial focuses on the following questions: What is its binding affinity toward a particular receptor? What are putative conformations of a ligand at the binding site? What are the similarities of different ligands in terms of their recognition capabilities? Where and in which orientation will a ligand bind to the active site? How is a new putative protein ligand selected? An overview is presented of the algorithms which are presently used to handle and predict protein-ligand interactions and to dock small molecule ligands into proteins.

  14. Neutron instrumentation for biology

    SciTech Connect (OSTI)

    Mason, S.A.

    1994-12-31

    In the October 1994 round of proposals at the ILL, the external biology review sub- committee was asked to allocate neutron beam time to a wide range of experiments, on almost half the total number of scheduled neutron instruments: on 3 diffractometers, on 3 small angle scattering instruments, and on some 6 inelastic scattering spectrometers. In the 3.5 years since the temporary reactor shutdown, the ILL`s management structure has been optimized, budgets and staff have been trimmed, the ILL reactor has been re-built, and many of the instruments up-graded, many powerful (mainly Unix) workstations have been introduced, and the neighboring European Synchrotron Radiation Facility has established itself as the leading synchrotron radiation source and has started its official user program. The ILL reactor remains the world`s most intense dedicated neutron source. In this challenging context, it is of interest to review briefly the park of ILL instruments used to study the structure and energetics of small and large biological systems. A brief summary will be made of each class of experiments actually proposed in the latest ILL proposal round.

  15. 6th Annual Systems Biology Symposium: Systems Biology and the Environment

    SciTech Connect (OSTI)

    Galitski, Timothy, P.

    2007-04-01

    Systems biology recognizes the complex multi-scale organization of biological systems, from molecules to ecosystems. The International Symposium on Systems Biology is an annual two-day event gathering the most influential researchers transforming biology into an integrative discipline investigating complex systems. In recognition of the fundamental similarity between the scientific problems addressed in environmental science and systems biology studies at the molecular, cellular, and organismal levels, the 2007 Symposium featured global leaders in “Systems Biology and the Environment.” The objective of the 2007 “Systems Biology and the Environment” International Symposium was to stimulate interdisciplinary thinking and research that spans systems biology and environmental science. This Symposium was well aligned with the DOE’s Genomics:GTL program efforts to achieve scientific objectives for each of the three DOE missions: • Develop biofuels as a major secure energy source for this century, • Develop biological solutions for intractable environmental problems, and • Understand biosystems’ climate impacts and assess sequestration strategies Our scientific program highlighted world-class research exemplifying these priorities. The Symposium featured 45 minute lectures from 12 researchers including: Penny/Sallie Chisholm of MIT gave the keynote address “Tiny Cells, Global Impact: What Prochlorococcus Can Teach Us About Systems Biology”, plus Jim Fredrickson of PNNL, Nitin Baliga of ISB, Steve Briggs of UCSD, David Cox of Perlegen Sciences, Antoine Danchin of Institut Pasteur, John Delaney of the U of Washington, John Groopman of Johns Hopkins, Ben Kerr of the U of Washington, Steve Koonin of BP, Elliott Meyerowitz of Caltech, and Ed Rubin of LBNL. The 2007 Symposium promoted DOE’s three mission areas among scientists from multiple disciplines representing academia, non-profit research institutions, and the private sector. As in all previous

  16. 2013 Biological Hydrogen Production Workshop Summary Report ...

    Energy Savers [EERE]

    Biological Hydrogen Production Workshop Summary Report 2013 Biological Hydrogen Production Workshop Summary Report November 2013 summary report for the 2013 Biological Hydrogen ...

  17. COLLOQUIUM: Plasma Mediated Effects on Biological Cells | Princeton Plasma

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Physics Lab October 8, 2014, 4:00pm to 5:30pm Colloquia MBG Auditorium COLLOQUIUM: Plasma Mediated Effects on Biological Cells Professor Mounir Laroussi Old Dominion University Low temperature plasma (LTP) in air-containing gas mixtures produce reactive oxygen species (ROS) such as O, O2-, and OH and reactive nitrogen species (RNS) such as NO and NO2 which exhibit strong oxidative properties and/or trigger signaling pathways in biological cells. For example oxidation of the lipids and

  18. FY2005 SSRLUO Executive Committee

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    SSRL Liaison Structural Molecular Biology corner corner Juana Acrivos CSU San Jose, ... Oregon Health Sciences University, Biochemistry & Molecular Biology, 3181 S.W. Sam Jackson ...

  19. Biology Division progress report, October 1, 1993--September 30, 1995

    SciTech Connect (OSTI)

    1995-10-01

    This Progress Report summarizes the research endeavors of the Biology Division of the Oak Ridge National Laboratory during the period October 1, 1993, through September 30, 1995. The report is structured to provide descriptions of current activities and accomplishments in each of the Division`s major organizational units. Lists of information to convey the entire scope of the Division`s activities are compiled at the end of the report. Attention is focused on the following research activities: molecular, cellular, and cancer biology; mammalian genetics and development; genome mapping program; and educational activities.

  20. Accelerated Molecular Dynamics Methods

    Broader source: Energy.gov [DOE]

    This presentation on Accelerated Molecular Dynamics Methods was given at the DOE Theory Focus Session on Hydrogen Storage Materials on May 18, 2006.

  1. William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) | U.S.

    Office of Science (SC) Website

    DOE Office of Science (SC) William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) Biological and Environmental Research (BER) BER Home About Research Biological Systems Science Division (BSSD) Climate and Environmental Sciences Division (CESD) ARM Climate Research Facility Atmospheric System Research (ASR) Program Data Management Earth System Modeling (ESM) Program William R. Wiley Environmental Molecular Sciences Laboratory (EMSL) Integrated Assessment of Global Climate Change

  2. Fermilab Today | University of Arizona

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    A&M University Dec. 12, 2012 NAME: Texas A&M University HOME TOWN: College Station, Texas MASCOT: Reveille COLORS: Maroon and white COLLABORATING AT FERMILAB SINCE: Early 1980s....

  3. Triangle Universities Nuclear Laboratory : 2011

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Hill KamLAND: Hugon Karwowski and Ryan Rohm, UNC at Chapel Hill; Christopher Gould and Albert Young, NC State University; Diane Markoff, NC Central University; and Werner Tornow,...

  4. Biological Safety | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Biological Select Agents Inspection Report: IG-0681, Concerns Regarding a Non-Viable (Dead) "Anthrax Sport" Research Project at the Oak Ridge National Laboratory Inspection ...

  5. Biological Applications of Synchrotron Radiation:

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Biological Applications of Synchrotron Radiation: An Evaluation of the State of the Field ... Maxwell's equations show that electromagnetic radiation is generated when charged ...

  6. Biological & Environmental Research Abstracts Database

    Office of Scientific and Technical Information (OSTI)

    Welcome to the Biological and Environmental Research Abstracts Database The U.S. ... This database contains abstracts of research projects supported by the program. Work was ...

  7. The Biological Implications of the PP2A Crystal Structure

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The Biological Implications of the PP2A Crystal Structure Print Phosphatases, enzymes that remove a phosphate group from amino-acid substrates, can be subdivided according to their substrate specificity. Myriad evidence has demonstrated that protein phosphatase 2A (PP2A), a family of serine/threonine-specific (Ser/Thr) phosphatases, regulates many, if not most, aspects of cellular activities and is a critical tumor suppressor. A team at the University of Washington recently determined the first

  8. The Biological Implications of the PP2A Crystal Structure

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The Biological Implications of the PP2A Crystal Structure Print Phosphatases, enzymes that remove a phosphate group from amino-acid substrates, can be subdivided according to their substrate specificity. Myriad evidence has demonstrated that protein phosphatase 2A (PP2A), a family of serine/threonine-specific (Ser/Thr) phosphatases, regulates many, if not most, aspects of cellular activities and is a critical tumor suppressor. A team at the University of Washington recently determined the first

  9. The Biological Implications of the PP2A Crystal Structure

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The Biological Implications of the PP2A Crystal Structure Print Phosphatases, enzymes that remove a phosphate group from amino-acid substrates, can be subdivided according to their substrate specificity. Myriad evidence has demonstrated that protein phosphatase 2A (PP2A), a family of serine/threonine-specific (Ser/Thr) phosphatases, regulates many, if not most, aspects of cellular activities and is a critical tumor suppressor. A team at the University of Washington recently determined the first

  10. Electronic Structure and Excited State Dynamics in Biological and Nanoscale

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Systems | MIT-Harvard Center for Excitonics Electronic Structure and Excited State Dynamics in Biological and Nanoscale Systems February 25, 2009 at 3pm/36-428 Gregory D. Scholes Department of Chemistry, University of Toronto scholes2 abstract: After photoexcitation, energy absorbed by a molecule can be transferred efficiently over a distance of up to several tens of Ångstrom to another molecule by the process of resonance energy transfer, RET (also commonly known as electronic energy

  11. The Biological Implications of the PP2A Crystal Structure

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    The Biological Implications of the PP2A Crystal Structure Print Phosphatases, enzymes that remove a phosphate group from amino-acid substrates, can be subdivided according to their substrate specificity. Myriad evidence has demonstrated that protein phosphatase 2A (PP2A), a family of serine/threonine-specific (Ser/Thr) phosphatases, regulates many, if not most, aspects of cellular activities and is a critical tumor suppressor. A team at the University of Washington recently determined the first

  12. In Situ Biological Uranium Remediation within a Highly Contaminated Aquifer

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    In Situ Biological Uranium Remediation within a Highly Contaminated Aquifer Matthew Ginder-Vogel1, Wei-Min Wu1, Jack Carley2, Phillip Jardine2, Scott Fendorf1 and Craig Criddle1 1Stanford University, Stanford, CA 2Oak Ridge National Laboratory, Oak Ridge, TN Microbial Respiration Figure 1. Uranium(VI) reduction is driven by microbial respiration resulting in the precipitation of uraninite. Uranium contamination of ground and surface waters has been detected at numerous sites throughout the

  13. UNIVERSITY OF CALIFORNIA

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Jean-Luc Vay With inputs from J. Amundson, J. Cary, W. Mori, C.-K. Ng, R. Ryne, J. Qiang Exascale Requirements Reviews: High Energy Physics June 10-12, 2015 Traditional HPC needs: particle accelerators 2 2 UNIVERSITY OF CALIFORNIA Office of Science Advanced s imula.ons p lay a n i ncreasingly i mportant r ole in the design, o pera.on and t uning o f a ccelerators. CERN ( HL---)LHC FNAL P IP(---II/III) "Conven.onal a ccelerators" accelerate b eams i n R F c avi.es "Advanced c

  14. THE UNIVERSITY' OF CHICAGO

    Office of Legacy Management (LM)

    .G: THE UNIVERSITY' OF CHICAGO DATE December 28, 194s I_ TO C. F. Hiskey DLP*Rr"LNT MUCtf=t+-3I ~ DEPARTMENT This document ConhtS Of...2, IN RE: Bloaaningtcn' Experiments pages and ._____._ L? ____ ~--~-~----7 Nos~f&COplES, Merle &aft Chicago on Sunday, Deccrmber 12, for Bloomington, Indian where I was to work in oonjuncticn with Dr. Mitohell. Carried along approxi- mately 1200 grams of D20. On Monday, Deomber 13, 8aue ne0eesW-y equi&.anent arrived from Chicago. was unpaoked,

  15. Drexel University Temperature Sensors

    SciTech Connect (OSTI)

    K. L. Davis; D. L. Knudson; J. L. Rempe; B. M. Chase

    2014-09-01

    This document summarizes background information and presents results related to temperature measurements in the Advanced Test Reactor (ATR) National Scientific User Facility (NSUF) Drexel University Project 31091 irradiation. The objective of this test was to assess the radiation performance of new ceramic materials for advanced reactor applications. Accordingly, irradiations of transition metal carbides and nitrides were performed using the Hydraulic Shuttle Irradiation System (HSIS) in the B-7 position and in static capsules inserted into the A-3 and East Flux Trap Position 5 locations of the ATR.

  16. Labs & Universities | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Michigan State University Minnesota, University of Mississippi State University Missouri, University of New Hampshire, University of New Mexico, University of New Mexico State ...

  17. psu-molecular-basket | netl.doe.gov

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    CO2 Capture from Flue Gas Using Solid Molecular Basket Sorbents Project No.: FE0000458 Pennsylvania State University (PSU) is developing a new generation of solid polymer-based sorbents for more efficient capture and separation of carbon dioxide (CO2) from flue gas of coal-fired power plants. The project is based on the concept of a "molecular basket" sorbent which was invented and developed at PSU. The idea of a molecular basket sorbent development is to load CO2-philic polymers

  18. Modular Construction - on a Molecular Scale | U.S. DOE Office of Science

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    (SC) Modular Construction - on a Molecular Scale Biological and Environmental Research (BER) BER Home About Research Facilities Science Highlights Searchable Archive of BER Highlights External link Benefits of BER Funding Opportunities Biological & Environmental Research Advisory Committee (BERAC) Community Resources Contact Information Biological and Environmental Research U.S. Department of Energy SC-23/Germantown Building 1000 Independence Ave., SW Washington, DC 20585 P: (301)

  19. University of Cape Town | Open Energy Information

    Open Energy Info (EERE)

    to: navigation, search Name: University of Cape Town Place: South Africa Product: Teaching and research university. References: University of Cape Town1 This article is a...

  20. Robert Gordon University | Open Energy Information

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    Gordon University Jump to: navigation, search Name: Robert Gordon University Address: Centre for Research in Energy and the Environment The Robert Gordon University Schoolhill...

  1. Case Western University | Open Energy Information

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    University Jump to: navigation, search Name Case Western University Facility Case Western University Sector Wind energy Facility Type Small Scale Wind Facility Status In Service...

  2. Polytechnic University of Madrid | Open Energy Information

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    Polytechnic University of Madrid Jump to: navigation, search Name: Polytechnic University of Madrid Place: Madrid, Spain Sector: Solar Product: University piloting a 2.7MW solar...

  3. North Carolina State University | Open Energy Information

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    University Jump to: navigation, search Name: North Carolina State University Place: Raleigh, North Carolina Zip: 27695 Sector: Biofuels, Biomass, Solar Product: Public university...

  4. Michigan State University | Open Energy Information

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    State University Jump to: navigation, search Name: Michigan State University Place: East Lansing, MI Website: www.michiganstateuniversity.co References: Michigan State University...

  5. Washington State University | Open Energy Information

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    University Jump to: navigation, search Name: Washington State University Place: Spokane, WA Website: www.washingtonstateuniversity. References: Washington State University1...

  6. Kansas State University | Open Energy Information

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    University Jump to: navigation, search Name Kansas State University Facility Kansas State University Sector Wind energy Facility Type Small Scale Wind Facility Status In Service...

  7. Fermilab Today | Johns Hopkins University Profile

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Hopkins University September 9, 2010 NAME: The Johns Hopkins University HOME TOWN: Baltimore, Maryland MASCOT: Blue jay SCHOOL COLORS: The university's official colors are gold...

  8. University Park Data Dashboard | Department of Energy

    Energy Savers [EERE]

    Data Dashboard University Park Data Dashboard The data dashboard for University Park, Maryland, a partner in the Better Buildings Neighborhood Program. University Park Data ...

  9. University of Delaware Wind | Open Energy Information

    Open Energy Info (EERE)

    search Name University of Delaware Wind Facility University of Delaware Wind Sector Wind energy Facility Type Community Wind Facility Status In Service Owner University of...

  10. University of Neuchatel | Open Energy Information

    Open Energy Info (EERE)

    Neuchatel Jump to: navigation, search Name: University of Neuchatel Place: Switzerland Product: The University of Neuchatel, Switzerland References: University of Neuchatel1 This...