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Sample records for module 1 privacy

  1. Privacy

    Broader source: Energy.gov [DOE]

    Welcome to the homepage of the Department of Energy, Privacy Office. Our mission is to assure the effective implementation of the Department of Energy Privacy Program. We’ve developed this section...

  2. PRIVACY IMPACT ASSESSMENT: Office

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Office of Information Resources - FOIAXpress Department of Energy Privacy Impact Assessment (PIA) Guidance is provided in the template. See DOE Order 206.1, Department of Energy Privacy Program, Appendix A, Privacy Impact Assessments, for requirements and additional guidance for conducting a PIA: http://www.directives.doe.gov/pdfs/doe/doetext/neword/206/02061.pdf Please complete electronically: no hand-written submissions will be accepted. This template may not be modified. MODULE 1- PRIVACY

  3. PRIVACY IMPACT ASSESSMENT: Occupational Medicine Assistant PIA

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Medicine - Assistant PIA Template Version 3 - May, 2009 Department of Energy Privacy Impact Assessment (PIA) Guidance is provided in the template. See DOE Order 206.1, Deparlment of Energy Privacy Program, Appendix A, Privacy Impact Assessments, for requirements and additional guidance for conducting a PIA: http://www.directives.doe.gov/pdfs/doe/doetextlneword/206/o2061.pdf Please complete electronically: no hand-written submissions will be accepted. This template may not be modified. MODULE 1-

  4. PRIVACY IMPACT ASSESSMENT: SPRO Physical Security Major Application

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    SPRO - Physical Security Major Application PIA Template Version 3 - May, 2009 Department of Energy Privacy Impact Assessment (PIA) Guidance is provided in the template. See DOE Order 206.1, Deparlment of Energy Privacy Program, Appendix A, Privacy Impact Assessments, for requirements and additional gUidance for conducting a PIA: http://www.directives.doe.gov/pdfs/doe/doetexUneword/206/o2061.pdf MODULE I - PRIVACY NEEDS ASSESSMENT Date Departmental Element & Site JUly 21, 2009 Office of

  5. WRAP module 1 treatment plan

    SciTech Connect (OSTI)

    Mayancsik, B.A.

    1995-05-01

    This document provides the methodology to treat waste in the Waste Receiving and Processing Module 1 facility to meet the Resource Conservation and Recovery Act (RCRA) land disposal restrictions or the Waste Isolation and Pilot Plant waste acceptance criteria. This includes Low-Level Mixed Waste, Transuranic Waste, and Transuranic Mixed Waste.

  6. Privacy Policy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    privacy policy Privacy Policy The National Energy Technology Laboratory strives to protect the privacy of website visitors. Information collected is strictly limited to the following: Information Collected and Stored Automatically The IP address, a number that is automatically assigned to each computer that connects to the World Wide Web Date and time of website access Pages browsed NETL reviews this information to help make the website more useful and informative. This information is used

  7. Privacy Resources

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Outreach Doing Business Expand Doing Business Skip navigation links Newsroom About Us Civil Rights - EEO Freedom of Information Act Investor Relations Library Privacy Request for...

  8. PRIVACY IMPACT ASSESSMENT: INL Communications

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Communications and Public Affairs Tour Tracker PIA Template Version 3 - May, 2009 Department of Energy Privacy Impact Assessment (PIA) Guidance is provided in the template. See DOE Order 206.1, Department of Energy Privacy Program, Appendix A, Privacy Impact Assessments, for reqUirements and additional guidance for conducting a PIA: http://www.directives.doe.gov/pdfs/doe/doetextlneword/206/o2061.pdf Please complete electronically: no hand-written submissions will be accepted. This template may

  9. Privacy Impact Assessment Template and Guidance

    Broader source: Energy.gov [DOE]

    Guidance is provided in the template. See DOE Order 206.1, Department of Energy Privacy Program, Appendix A, Privacy Impact Assessments, for requirements and additional guidance for conducting an...

  10. WRAP Module 1 sampling and analysis plan

    SciTech Connect (OSTI)

    Mayancsik, B.A.

    1995-03-24

    This document provides the methodology to sample, screen, and analyze waste generated, processed, or otherwise the responsibility of the Waste Receiving and Processing Module 1 facility. This includes Low-Level Waste, Transuranic Waste, Mixed Waste, and Dangerous Waste.

  11. Best Practices: Elements of a Federal Privacy Program

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Best Practices: Elements of a Federal Privacy Program Version 1.0 Sponsored By: Federal CIO Council Privacy Committee June 2010 Best Practices: Elements of a Federal Privacy Program June 2010 Page i Contents Acknowledgements __________________________________________________________________ ii Purpose ____________________________________________________________________________ 1 Introduction: Privacy Stewardship and Governance _________________________________________ 3 Element 1 -Leadership

  12. Privacy | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Services » Guidance » Privacy Privacy A yellow marker highlighting the word, "privacy." A yellow marker highlighting the word, "privacy." Welcome to the Department of Energy Privacy Program Office. The DOE Privacy Program is based on the Privacy Act of 1974, as implemented by Office of Management and Budget Circular A-130, the E-Government Act of 2002, and Departmental policies. The objective of the Program is to balance the information requirements and operational needs of

  13. PRIVACY IMPACT ASSESSMENT: OFFICE OF LEGACY MANAGEMENT: RECORDS

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    '" " * .1 * PRIVACY IMPACT ASSESSMENT: OFFICE OF LEGACY MANAGEMENT: RECORDS HANDLING SYSTEM: FREEDOM OF INFORMAnON ACT/ PRIVACY ACT PIA Template Version - May, 2009 Department of Energy Privacy Impact Assessment (PIA) Guidance is provided in the template. See DOE Order 206.1, Department of Energy Privacy Program, Appendix A, Privacy Impact Assessments, for requirements and additional guidance for conducting a PIA: http://www.directives.doe.gov/pdfs/doe/doetextlneword/206/02061.pdf

  14. Privacy Act of 1974; Publication of Compilation of Privacy Act...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Privacy Act of 1974; Publication of Compilation of Privacy Act Systems of Records Privacy Act of 1974; Publication of Compilation of Privacy Act Systems of Records Privacy Act of ...

  15. WRAP Module 1 waste characterization plan

    SciTech Connect (OSTI)

    Mayancsik, B.A.

    1995-01-23

    The purpose of this document is to present the characterization methodology for waste generated, processed, or otherwise the responsibility of the Waste Receiving and Processing (WRAP) Module 1 facility. The scope of this document includes all solid low level waste (LLW), transuranic (TRU), mixed waste (MW), and dangerous waste. This document is not meant to be all-inclusive of the waste processed or generated within WRAP Module 1, but to present a methodology for characterization. As other streams are identified, the method of characterization will be consistent with the other streams identified in this plan. The WRAP Module 1 facility is located in the 200 West Area of the Hanford Site. The facility`s function is two-fold. The first is to verify/characterize, treat and repackage contact handled (CH) waste currently in retrievable storage in the LLW Burial Grounds, Hanford Central Waste Complex, and the Transuranic Storage and Assay Facility (TRUSAF). The second is to verify newly generated CH TRU waste and LLW, including MW. The WRAP Module 1 facility provides NDE and NDA of the waste for both drums and boxes. The NDE is used to identify the physical contents of the waste containers to support waste characterization and processing, verification, or certification. The NDA results determine the radioactive content and distribution of the waste.

  16. Data Privacy Day

    Broader source: Energy.gov [DOE]

    Respecting Privacy, Safeguarding Data and Enabling Trust is the theme for Data Privacy Day (DPD), an international effort held annually on January 28 to create awareness about the importance of privacy and protecting personal information.

  17. Elements of a Federal Privacy Program | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Elements of a Federal Privacy Program Elements of a Federal Privacy Program The seven elements described in this document provide the basis for a robust federal privacy program, and will assist federal organizations to implement and sustain privacy awareness and stewardship. Elements of a Federal Privacy Program v1.0_June2010 Final.pdf (569.77 KB) More Documents & Publications PIA - GovTrip (DOE data) PIA - INL PeopleSoft - Human Resource System Energy Employees' Occupational Illness

  18. PRIVACY IMPACT ASSESSMENT: OCCUPATIONAL MEDICINE- INL OCCUPATIONAL

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    OCCUPATIONAL MEDICINE- INL OCCUPATIONAL MEDICAL SUVEILLANCE SYSTEM (OMSS) PIA Template Version 3 - May, 2009 Department of Energy Privacy Impact Assessment (PIA) Guidance is provided in the template. See DOE Order 206.1, Department of Energy Privacy Program, Appendix A, Privacy Impact Assessments, for requirements and additional guidance for conducting a PIA: http://www.directives.doe.gov/pdfs/doe/doetextlneword/206/o2061.pdf Please complete electronically: no hand-written submissions will be

  19. PRIVACY IMPACT ASSESSMENT: OCIO HSPD-12 Physical

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    OCIO - HSPD-12 Physical and Logical System PIA Template Version 4- June, 2009 Department of Energy Privacy Impact Assessment (PIA) Guidance is provided in the template. See DOE Order 206.1, Department of Energy Privacy Program, Appendix A, Privacy Impact Assessments, for requirements and additional guidance for conducting a PIA: http://www.directives.doe.gov/pdfs/doe/doetextlneword/206/o2061.pdf Please complete electronically: no hand-written submissions will be accepted. This template may not

  20. PRIVACY IMPACT ASSESSMENT: Occupational Safety Health Occupational

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Occupational Safety & Health - Occupational Injury & Illness System PIA Template Version 3 - May, 2009 Department of Energy Privacy Impact Assessment (PIA) Guidance is provided in the template. See DOE Order 206.1 J Department of Energy Privacy Program, Appendix A, Privacy Impact Assessments, for requirements and additional guidance for conducting a PIA: http://www.directives.doe.gov/pdfs/doe/doetextlneword/206/o2061.pdf Please complete electronically: no hand-written submissions will be

  1. PRIVACY IMPACT ASSESSMENT: OFFICE OF LEGACY MANAGEMENT: RECORDS

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    .. ,. - -i * PRIVACY IMPACT ASSESSMENT: OFFICE OF LEGACY MANAGEMENT: RECORDS HANDLING SYSTEM: FERNALD HISTORICAL RECORDS SYSTEM PIA Template Version - May, 2009 Department of Energy Privacy Impact Assessment (PIA) Guidance is provided in the template. See DOE Order 206.1, Department of Energy Privacy Program, Appendix A, Privacy Impact Assessments, for requirements and additional guidance for conducting a PIA: http://www.directives.doe.gov/pdfs/doe/doetextlneword/206/02061.pdf Please complete

  2. PRIVACY IMPACT ASSESSMENT: OFFICE OF LEGACY MANAGEMENT: RECORDS

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    :-. ., ,-- -.' * PRIVACY IMPACT ASSESSMENT: OFFICE OF LEGACY MANAGEMENT: RECORDS HANDLING SYSTEM: ELECTRONIC RECORDS KEEPING SYSTEM PIA Template Version - May, 2009 Department of Energy Privacy Impact Assessment (PIA) Guidance is provided in the template. See DOE Order 206.1. Department of Energy Privacy Program, Appendix A. Privacy Impact Assessments. for requirements and additional guidance for conducting a PIA: http://www.directives.doe.gov/pdfs/doe/doetext/neword/206/02061.pdf Please

  3. PRIVACY IMPACT ASSESSMENT: Shaw Areva MOX Services, LLC MOX

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    . ,-) ')7 73?¥i5": )~"'f"YC-:;'~dt?f(~"'f9'FrrZ , . PRIVACY IMPACT ASSESSMENT: Shaw Areva MOX Services, LLC MOX Services Unclassified Information System Template - January 30, 2009, Version 2 Department of Energy Privacy Impact Assessment (pIA) Guidance is provided in the template. See DOE Order 206.1, Department of Energy Privacy Program, Appendix A, Privacy Impact Assessments, for requirements and additional guidance for conducting a PIA:

  4. Privacy Impact Assessment (PIA) Template and Guidance | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Privacy Impact Assessment (PIA) Template and Guidance Privacy Impact Assessment (PIA) Template and Guidance Privacy_Impact_Assessment_Template_May_2009_w_Guidance.docx (1.74 MB) More Documents & Publications Manchester Software 1099 Reporting PIA, Idaho National Laboratory Occupational Medicine - Assistant PIA, Idaho National Laboratory Integrated Safety Management Workshop Registration, PIA, Idaho National Laboratory

  5. General Privacy Act Guidance | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Privacy Act Guidance General Privacy Act Guidance This document provides information on Privacy Act Requests and responses to general FAQs PDF icon General Privacy Act Guidance ...

  6. FOIA, The Privacy Act

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    FOIA, the Privacy Act Your Rights under the FOIA, the Privacy Act, and other Privacy Laws The Freedom of Information Act and Privacy Act Division/Office is responsible for administering policies, programs, and procedures to ensure DOE compliance with the Freedom of Information Act (FOIA) and the Privacy Act (PA), 5 U.S.C. 552 and 5 U.S.C. 552a, respectively. The resources on these pages are provided to aid in finding answers to your questions about programs of the Department of Energy and to

  7. Waste receiving and processing facility module 1 auditable safetyanalysis

    SciTech Connect (OSTI)

    Bottenus, R.J.

    1997-02-01

    The Waste Receiving and Processing Facility Module 1 Auditable Safety Analysis analyzes postulated accidents and determines controls to prevent the accidents or mitigate the consequences.

  8. WIPP Privacy Policy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    WIPP Privacy Policy and Disclaimers NOTICE: The Waste Isolation Pilot Plant (WIPP) Internet Server is provided as a service of the Department of Energy (DOE) for distribution of...

  9. Privacy | Department of Energy

    Energy Savers [EERE]

    Privacy Notice Energy.gov utilizes web measurement technology in order to improve our ... since we are utilizing a multi-session web measurement technology that does not ...

  10. DOE Privacy Steering Committee Charter

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Privacy Steering Committee Charter A. OBJECTIVE The purpose of the Department of Energy (DOE) Privacy Steering Committee (EPSC) is to advise the Senior Agency Official for Privacy (SAOP) and the Department's Privacy Program, providing recommendations to improve policies and program initiatives including breach response and notification, Privacy Impact Assessments, and other privacy matters. The EPSC is an essential component of DOE's ongoing efforts to identify processes to eliminate the

  11. DOE Privacy Program Brochure | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Privacy Program Brochure DOE Privacy Program Brochure Employee Guide to Privacy (79 KB) More Documents & Publications DEPARTMENT OF ENERGY Privacy Awareness Training Audit Report: IG-0771 Elements of a Federal Privacy Program

  12. Modules

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Modules Modules Modules Approach to Managing The Environment Modules is a system which you can use to specify what software you want to use. If you want to use a particular software package loading its module will take care of the details of modifying your environment as necessary. The advantage of the modules approach is that the you are not required to explicitly specify paths for different executable versions and try to keep their related man paths and environment variables coordinated.

  13. DOE - NNSA/NFO -- Privacy Act Exemptions

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Privacy Act > Exemptions NNSA/NFO Language Options U.S. DOE/NNSA - Nevada Field Office Privacy Act Exemptions subject to the provisions of section 552(b)(1) of the Freedom of Information Act (information properly classified in the interest of national security or foreign policy); investigatory material compiled for law enforcement purposes other than those spelled out in the general exemption; maintained in connection with providing protective services to the President of the United States or

  14. The Privacy Act of 1974

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Privacy Act of 1974 The Privacy Act of 1974, 5 U.S.C. §552a, governs an agency's collection, storage, and use of information about an individual. The Privacy Act protects the privacy of individuals by establishing fair information practices for the collection, maintenance, use, and dissemination of information by federal agencies. Frequently Asked Questions Who is an individual for the purposes of the Privacy Act? A (living) citizen of the United States or an alien lawfully admitted for

  15. Privacy Points of Contact | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    Microsoft Word - PrivacyContactListingSeptember212010 More Documents & Publications Privacy Act Officers Contact LIst DOE Privacy Program Contact Listing as of September 21,...

  16. PRIVACY IMPACT ASSESSMENT: OFFICE OF LEGACY MANAGEMENT: RECORDS

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    OFFICE OF LEGACY MANAGEMENT: RECORDS HANDLING SYSTEM: ENERGY EMPLOYEES OCCUPATIONAL ILLNESS COMPENSATION PROGRAM ACT PIA Template Version - May, 2009 Department of Energy Privacy Impact Assessment (PIA) Guidance Is provided in the template. See DOE Order 206.1, Department of Energy Privacy Program, Appendix A, Privacy Impact Assessments, for requirements and additional guidance for conducting a PIA: http://www.directives.doe.gov/pdfs/doe/doetextlneword/206/02061.pdf Please complete

  17. WIPP - Privacy Act of 1974

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Privacy Act Quick Links Affidavit For Surviving Relative Request for Report of Radiation Exposure History 5 U.S.C. § 552a 10 CFR 1008 Privacy Act of 1974 TABLE OF CONTENTS HOW TO MAKE A PRIVACY ACT REQUEST WITH THE U. S. DEPARTMENT OF ENERGY CARLSBAD FIELD OFFICE PRIVACY ACT OVERVIEW DISCLOSURE OF PERSONAL INFORMATION VIOLATIONS EXEMPTIONS FEES AND TIME LIMITS LINKS TO OTHER INTERESTING SITES HOW TO MAKE A PRIVACY ACT REQUEST WITH THE U. S. DEPARTMENT OF ENERGY CARLSBAD FIELD OFFICE Privacy Act

  18. DEPARTMENT OF ENERGY DATA ACCESS AND PRIVACY ISSUES RELATED TO SMART GRID

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    DEPARTMENT OF ENERGY DATA ACCESS AND PRIVACY ISSUES RELATED TO SMART GRID TECHNOLOGIES October 5, 2010 i TABLE OF CONTENTS INTRODUCTION AND EXECUTIVE SUMMARY.................................................................... 1 Overview of Data Access and Privacy Concerns ....................................................................... 2 Summary of Recommendations .................................................................................................. 3 KEY FINDINGS

  19. Energy Privacy Steering Committee | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Privacy Steering Committee Energy Privacy Steering Committee The Department of Energy (DOE) Privacy Steering Committee (EPSC) advises the Senior Agency Official for Privacy (SAOP) and the Department's Privacy Program regarding policies and program initiatives including breach response and notification, Privacy Impact Assessments, and other privacy matters. DOE Privacy Steering Committee Charter (23.37 KB) More Documents & Publications PIA - INL PeopleSoft - Human Resource System DOE

  20. Department of Energy Idaho - Privacy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Web Policies No Fear Act Site Map Privacy Phone Book You are here: DOE-ID Home > Privacy ... We collect no personal information about you when you visit a DOE Web site, unless ...

  1. Waste Receiving and Processing (WRAP) Module 1 Hazards Assessment

    SciTech Connect (OSTI)

    CAMPBELL, L.R.

    1999-09-29

    This document establishes the technical basis in support of Emergency Planning activities for the WRAP Module 1 Facility on the Hanford Site. Through this document, the technical basis for the development of facility specific Emergency Action Levels and Emergency Planning Zone is demonstrated.

  2. Making a Privacy Act Request - Hanford Site

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Making a Privacy Act Request Freedom of Information and Privacy Act DOE Headquarters FOIA Web Page A Citizen's Guide to the FOIA and Privacy Act Making a Privacy Act Request Freedom of Information Act, 5 U.S.C. Freedom of Information Act Regulations Privacy Act Regulations DOE Public Reading Room PNNL Technical Library Electronic FOIA Reading Room Freedom of Information Act & Privacy Act Contacts Records Previously Disclosed Helpful Links FOIA Home Making a Privacy Act Request Email Email

  3. PRIVACY IMPACT ASSESSMENT: INL INGSM2009 PIA Template Version

    Office of Environmental Management (EM)

    ... Data is encrypted at rest and while in transit. Has there .ben any attempt to verify PII does not exist on the I) 1 I " ( : ') 1) '1 l I . Il 'I Yes 2 * system? PRIVACY ...

  4. Module 1 - Introduction to Earned Value | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    and defines the framework necessary for proper Earned Value management implementation. ... Module 7 - Integrated Baseline Review and Change Control Module 8 - Reporting

  5. Privacy Act of 1974; Publication of Compilation of Privacy Act Systems of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Records | Department of Energy Privacy Act of 1974; Publication of Compilation of Privacy Act Systems of Records Privacy Act of 1974; Publication of Compilation of Privacy Act Systems of Records Privacy Act of 1974; Publication of Compilation of Privacy Act Systems of Records Privacy Act of 1974; Publication of Compilation of Privacy Act Systems of Records (524.84 KB) More Documents & Publications Federal Register Document, Federal Register / Vol. 69, No. 17 / Tuesday, January 27, 2004 /

  6. Beam Propagator for Weather Radars, Modules 1 and 2

    Energy Science and Technology Software Center (OSTI)

    2013-10-08

    This program simulates the beam propagation of weather radar pulses under particular and realistic atmospheric conditions (without using the assumption of standard refraction conditions). It consists of two modules: radiosondings_refract_index_many.pro (MAIN MODULE) beam_propagation_function.pro(EXTERNAL FUNCTION) FOR THE MAIN MODULE, THE CODE DOES OUTPUT--INTO A FILE--THE BEAM HEIGHT AS A FUNCTION OF RANGE. THE RADIOSONDE INPUT FILES SHOULD BE ALREADY AVAILABLE BY THE USER. FOR EXAMPLE, RADIOSONDE OBSERVATION FILES CAN BE OBTAINED AT: RADIOSONDE OBSERVATIONS DOWNLOADED ATmore » "http://weather.uwyo.edu/upperair/soounding.html" OR "http://jervis.pyr.ec.gc.ca" THE EXTERNAL FUNCTION DOES THE ACTUAL COMPUTATION OF BEAM PROPAGATION. IT INCLUDES CONDITIONS OF ANOMALOUS PROPAGATION AND NEGATIVE ELEVATION ANGLES. THE EQUATIONS USED HERE WERE DERIVED BY EDWIN CAMPOS, BASED ON THE SNELL-DESCARTES LAW OF REFRACTION, CONSIDERING THE EARTH CURVATURE. THE PROGRAM REQUIRES A COMPILER FOR THE INTERACTIVE DATA LANGUAGE (IDL). DESCRIPTION AND VALIDATION DETAILS HAVE BEEN PUBLISHED IN THE PEER-REVIEWED SCIENTIFIC LITERATURE, AS FOLLOWS: Campos E. 2012. Estimating weather radar coverage over complex terrain, pp.26-32, peer reviewed, in Weather Radar and Hydrology, edited by Moore RJ, Cole SJ and Illingworth AJ. International Association of Hydrological Sciences (IAHS) Press, IAHS Publ. 351. ISBN 978-1-907161-26-1.« less

  7. Brg1 modulates enhancer activation in mesoderm lineage commitment

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Alexander, Jeffrey M.; Hota, Swetansu K.; He, Daniel; Thomas, Sean; Ho, Lena; Pennacchio, Len A.; Bruneau, B. G.

    2015-03-26

    The interplay between different levels of gene regulation in modulating developmental transcriptional programs, such as histone modifications and chromatin remodeling, is not well understood. Here, we show that the chromatin remodeling factor Brg1 is required for enhancer activation in mesoderm induction. In an embryonic stem cell-based directed differentiation assay, the absence of Brg1 results in a failure of cardiomyocyte differentiation and broad deregulation of lineage-specific gene expression during mesoderm induction. We find that Brg1 co-localizes with H3K27ac at distal enhancers and is required for robust H3K27 acetylation at distal enhancers that are activated during mesoderm induction. Brg1 is also requiredmore » to maintain Polycomb-mediated repression of non-mesodermal developmental regulators, suggesting cooperativity between Brg1 and Polycomb complexes. Thus, Brg1 is essential for modulating active and repressive chromatin states during mesoderm lineage commitment, in particular the activation of developmentally important enhancers. In conclusion, these findings demonstrate interplay between chromatin remodeling complexes and histone modifications that, together, ensure robust and broad gene regulation during crucial lineage commitment decisions.« less

  8. Brg1 modulates enhancer activation in mesoderm lineage commitment

    SciTech Connect (OSTI)

    Alexander, Jeffrey M.; Hota, Swetansu K.; He, Daniel; Thomas, Sean; Ho, Lena; Pennacchio, Len A.; Bruneau, B. G.

    2015-03-26

    The interplay between different levels of gene regulation in modulating developmental transcriptional programs, such as histone modifications and chromatin remodeling, is not well understood. Here, we show that the chromatin remodeling factor Brg1 is required for enhancer activation in mesoderm induction. In an embryonic stem cell-based directed differentiation assay, the absence of Brg1 results in a failure of cardiomyocyte differentiation and broad deregulation of lineage-specific gene expression during mesoderm induction. We find that Brg1 co-localizes with H3K27ac at distal enhancers and is required for robust H3K27 acetylation at distal enhancers that are activated during mesoderm induction. Brg1 is also required to maintain Polycomb-mediated repression of non-mesodermal developmental regulators, suggesting cooperativity between Brg1 and Polycomb complexes. Thus, Brg1 is essential for modulating active and repressive chromatin states during mesoderm lineage commitment, in particular the activation of developmentally important enhancers. In conclusion, these findings demonstrate interplay between chromatin remodeling complexes and histone modifications that, together, ensure robust and broad gene regulation during crucial lineage commitment decisions.

  9. DOE - NNSA/NFO -- Privacy Act Information

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Privacy Act Information NNSANFO Language Options U.S. DOENNSA - Nevada Field Office Privacy Act Overview The Privacy Act of 1974, Title 5, United States Code, Section 552a, ...

  10. Request for Privacy Act Records

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Outreach Doing Business Expand Doing Business Skip navigation links Newsroom About Us Civil Rights - EEO Freedom of Information Act Investor Relations Library Privacy Request for...

  11. Privacy, Security, & Legal Disclaimer Notice - Hanford Site

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Privacy, Security, & Legal Disclaimer Notice About Us About Hanford Cleanup Hanford History Hanford Site Wide Programs Contact Us Privacy, Security, & Legal Disclaimer Notice Email...

  12. YY1 modulates taxane response in epithelial ovarian cancer

    SciTech Connect (OSTI)

    Matsumura, Noriomi; Huang, Zhiqing; Baba, Tsukasa; Lee, Paula S.; Barnett, Jason C.; Mori, Seiichi; Chang, Jeffrey T.; Kuo, Wen-Lin; Gusberg, Alison H.; Whitaker, Regina S.; Gray, JoeW.; Fujii, Shingo; Berchuck, Andrew; Murphy, Susan K.

    2008-10-10

    The results of this study show that a high YY1 gene signature (characterized by coordinate elevated expression of transcription factor YY1 and putative YY1 target genes) within serous epithelial ovarian cancers is associated with enhanced response to taxane-based chemotherapy and improved survival. If confirmed in a prospective study, these results have important implications for the potential future use of individualized therapy in treating patients with ovarian cancer. Identification of the YY1 gene signature profile within a tumor prior to initiation of chemotherapy may provide valuable information about the anticipated response of these tumors to taxane-based drugs, leading to better informed decisions regarding chemotherapeutic choice. Survival of ovarian cancer patients is largely dictated by their response to chemotherapy, which depends on underlying molecular features of the malignancy. We previously identified YIN YANG 1 (YY1) as a gene whose expression is positively correlated with ovarian cancer survival. Herein we investigated the mechanistic basis of this association. Epigenetic and genetic characteristics of YY1 in serous epithelial ovarian cancer (SEOC) were analyzed along with YY1 mRNA and protein. Patterns of gene expression in primary SEOC and in the NCI60 database were investigated using computational methods. YY1 function and modulation of chemotherapeutic response in vitro was studied using siRNA knockdown. Microarray analysis showed strong positive correlation between expression of YY1 and genes with YY1 and transcription factor E2F binding motifs in SEOC and in the NCI60 cancer cell lines. Clustering of microarray data for these genes revealed that high YY1/E2F3 activity positively correlates with survival of patients treated with the microtubule stabilizing drug paclitaxel. Increased sensitivity to taxanes, but not to DNA crosslinking platinum agents, was also characteristic of NCI60 cancer cell lines with a high YY1/E2F signature. YY1

  13. U.S. DEPARTMENT OF ENERGY PRIVACY ACT INFORMATION REQUEST

    National Nuclear Security Administration (NNSA)

    Privacy Act Officer at the U.S. Department of Energy Headquarters or Field location. ... copy; sends original to the Department of Energy DOE F 531 (082013) Replaces DOE F 1800.1 ...

  14. Department of Energy Privacy Program

    Broader source: Directives, Delegations, and Requirements [Office of Management (MA)]

    2009-01-16

    The order establishes Departmental implementation of agency statutory and regulatory requirements for privacy, specifically those provided in the Privacy Act of 1974, as amended at Title 5 United States Code (U.S.C.) 552a, Section 208 of the E Government Act of 2002, and Office of Management and Budget directives. Cancels DOE N 206.5.

  15. PRIVACY/SECURITY NOTICE

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    PRIVACY/SECURITY NOTICE By continuing to use this system you indicate your awareness of and consent to the following terms and conditions of use. LOG OFF IMMEDIATELY if you do not agree to the conditions stated in this warning. SECURITY NOTICE This Web site is part of a Federal computer system used to accomplish Federal functions. The Department of Energy monitors this Web site for security purposes to ensure it remains available to all users and to protect information in the system. The system

  16. Order Module--DOE O 151.1C, COMPREHENSIVE EMERGENCY MANAGEMENT SYSTEM

    Broader source: Energy.gov [DOE]

    The familiar level of this module is designed to summarize the basic information in DOE O 151.1C, Comprehensive Emergency Management System. This module is divided into two sections. in the first...

  17. Implementation plan for WRAP Module 1 operational readiness review

    SciTech Connect (OSTI)

    Irons, L.G.

    1994-11-04

    The Waste Receiving and Processing Module 1 (WRAP 1) will be used to receive, sample, treat, and ship contact-handled (CH) transuranic (TRU), low-level waste (LLW), and low-level mixed waste (LLMW) to storage and disposal sites both on the Hanford site and off-site. The primary mission of WRAP 1 is to characterize and certify CH waste in 55-gallon and 85-gallon drums; and its secondary function is to certify CH waste standard waste boxes (SWB) and boxes of similar size for disposal. The WRAP 1 will provide the capability for examination (including x-ray, visual, and contents sampling), limited treatment, repackaging, and certification of CH suspect-TRU waste in 55-gallon drums retrieved from storage, as well as newly generated CH LLW and CH TRU waste drums. The WRAP 1 will also provide examination (X-ray and visual only) and certification of CH LLW and CH TRU waste in small boxes. The decision to perform an Operational Readiness Review (ORR) was made in accordance with WHC-CM-5-34, Solid Waste Disposal Operations Administration, Section 1.4, Operational Readiness Activities. The ORR will ensure plant and equipment readiness, management and personnel readiness, and management programs readiness for the initial startup of the facility. This implementation plan is provided for defining the conduct of the WHC ORR.

  18. PREDICTS 1: Results of Module-Level Power Electronics Accelerated...

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... attached PV modules in the field under normal usage conditions. ... About Energy & Climate News Events Publications Image Library Video Library Facilities Fact Sheets Contact Us ...

  19. BPD Privacy Terms | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Privacy Terms BPD Privacy Terms The Building Performance Database Privacy Terms. This document must be reviewed and accepted when submitting data for use in the BPD. BPD Privacy Terms.pdf (143.9 KB) More Documents & Publications Buildings Performance Database Overview BPD Security Buildings Performance Database - 2013

  20. Photovoltaic Module Reliability Workshop 2012: February 28 - March 1, 2012

    SciTech Connect (OSTI)

    Kurtz, S.

    2013-11-01

    NREL's Photovoltaic (PV) Module Reliability Workshop (PVMRW) brings together PV reliability experts to share information, leading to the improvement of PV module reliability. Such improvement reduces the cost of solar electricity and promotes investor confidence in the technology--both critical goals for moving PV technologies deeper into the electricity marketplace.

  1. DOE Privacy Program Contact Listing as of September 21, 2010...

    Broader source: Energy.gov (indexed) [DOE]

    DOE Privacy Program Contact Listing as of September 21, 2010 DOE Privacy Program Contact Listing as of September 21, 2010 More Documents & Publications Privacy Act Officers Contact...

  2. WRAP Module 1 sampling strategy and waste characterization alternatives study

    SciTech Connect (OSTI)

    Bergeson, C.L.

    1994-09-30

    The Waste Receiving and Processing Module 1 Facility is designed to examine, process, certify, and ship drums and boxes of solid wastes that have a surface dose equivalent of less than 200 mrem/h. These wastes will include low-level and transuranic wastes that are retrievably stored in the 200 Area burial grounds and facilities in addition to newly generated wastes. Certification of retrievably stored wastes processing in WRAP 1 is required to meet the waste acceptance criteria for onsite treatment and disposal of low-level waste and mixed low-level waste and the Waste Isolation Pilot Plant Waste Acceptance Criteria for the disposal of TRU waste. In addition, these wastes will need to be certified for packaging in TRUPACT-II shipping containers. Characterization of the retrievably stored waste is needed to support the certification process. Characterization data will be obtained from historical records, process knowledge, nondestructive examination nondestructive assay, visual inspection of the waste, head-gas sampling, and analysis of samples taken from the waste containers. Sample characterization refers to the method or methods that are used to test waste samples for specific analytes. The focus of this study is the sample characterization needed to accurately identify the hazardous and radioactive constituents present in the retrieved wastes that will be processed in WRAP 1. In addition, some sampling and characterization will be required to support NDA calculations and to provide an over-check for the characterization of newly generated wastes. This study results in the baseline definition of WRAP 1 sampling and analysis requirements and identifies alternative methods to meet these requirements in an efficient and economical manner.

  3. Transparent building-integrated PV modules. Phase 1: Comprehensive report

    SciTech Connect (OSTI)

    NONE

    1998-09-28

    This Comprehensive Report encompasses the activities that have been undertaken by Kiss + Cathcart, Architects, in conjunction with Energy Photovoltaics, Incorporated (EPV), to develop a flexible patterning system for thin-film photovoltaic (PV) modules for building applications. There are two basic methods for increasing transparency/light transmission by means of patterning the PV film: widening existing scribe lines, or scribing a second series of lines perpendicular to the first. These methods can yield essentially any degree of light transmission, but both result in visible patterns of light and dark on the panel surface. A third proposed method is to burn a grid of dots through the films, independent of the normal cell scribing. This method has the potential to produce a light-transmitting panel with no visible pattern. Ornamental patterns at larger scales can be created using combinations of these techniques. Kiss + Cathcart, Architects, in conjunction with EPV are currently developing a complementary process for the large-scale lamination of thin-film PVs, which enables building integrated (BIPV) modules to be produced in sizes up to 48 in. x 96 in. Flexible laser patterning will be used for three main purposes, all intended to broaden the appeal of the product to the building sector: To create semitransparent thin-film modules for skylights, and in some applications, for vision glazing.; to create patterns for ornamental effects. This application is similar to fritted glass, which is used for shading, visual screening, graphics, and other purposes; and to allow BIPV modules to be fabricated in various sizes and shapes with maximum control over electrical characteristics.

  4. Order Module--DOE O 433.1B, MAINTENANCE MANAGEMENT PROGRAM FOR...

    Office of Environmental Management (EM)

    3.1B, MAINTENANCE MANAGEMENT PROGRAM FOR DOE NUCLEAR FACILITIES Order Module--DOE O 433.1B, MAINTENANCE MANAGEMENT PROGRAM FOR DOE NUCLEAR FACILITIES "The familiar level of this ...

  5. Order Module--DOE O 460.1C, PACKAGING AND TRANSPORTATION SAFETY...

    Office of Environmental Management (EM)

    60.1C, PACKAGING AND TRANSPORTATION SAFETY, DOE O 460.2A, DEPARTMENTAL MATERIALS TRANSPORTATION AND PACKAGING MANAGEMENT Order Module--DOE O 460.1C, PACKAGING AND TRANSPORTATION...

  6. Order Module--DOE O 435.1 RADIOACTIVE WASTE MANAGEMENT | Department...

    Office of Environmental Management (EM)

    35.1 RADIOACTIVE WASTE MANAGEMENT Order Module--DOE O 435.1 RADIOACTIVE WASTE MANAGEMENT DOE Order 5820.2A, Radioactive Waste Management, was issued by DOE in September 1988. As ...

  7. Order Module--DOE O 433.1B, MAINTENANCE MANAGEMENT PROGRAM FOR DOE NUCLEAR

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    FACILITIES | Department of Energy 3.1B, MAINTENANCE MANAGEMENT PROGRAM FOR DOE NUCLEAR FACILITIES Order Module--DOE O 433.1B, MAINTENANCE MANAGEMENT PROGRAM FOR DOE NUCLEAR FACILITIES "The familiar level of this module is designed to summarize the basic information in DOE O 433.1B, Maintenance Management Program for DOE Nuclear Facilities. This Order canceled DOE O 433.1A. This module is divided into three sections. Section one contains the objective, general requirements, and the

  8. Order Module--DOE O 440.1B, WORKER PROTECTION PROGRAM FOR DOE (INCLUDING

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    NNSA) FEDERAL EMPLOYEES | Department of Energy 40.1B, WORKER PROTECTION PROGRAM FOR DOE (INCLUDING NNSA) FEDERAL EMPLOYEES Order Module--DOE O 440.1B, WORKER PROTECTION PROGRAM FOR DOE (INCLUDING NNSA) FEDERAL EMPLOYEES The familiar level of this module is divided into two sections. In the first section, we will discuss the objective, requirements, and the responsibilities assigned to the heads of field elements. In the second section, we will discuss the content of attachment 1, Functional

  9. "Order Module--DOE O 442.1, DEPARTMENT OF ENERGY EMPLOYEE CONCERNS PROGRAM

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    | Department of Energy "Order Module--DOE O 442.1, DEPARTMENT OF ENERGY EMPLOYEE CONCERNS PROGRAM "Order Module--DOE O 442.1, DEPARTMENT OF ENERGY EMPLOYEE CONCERNS PROGRAM The familiar level of this module is divided into two sections. In the first section, we will discuss the objectives, requirements, responsibilities, and definitions that are contained in the Order. In the second section, we will discuss the Guide. There is only one level of instruction for this Order. You will

  10. Order Module--DOE O 440.1B, WORKER PROTECTION PROGRAM FOR DOE...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    The practice will also help prepare you for the criterion test. DOE Order Self Study Modules - DOE O 440.1B, Worker Protection Management for DOE (Including the National Nuclear ...

  11. DOE Order Self Study Modules - DOE O 440.1B, Worker Protection...

    Office of Environmental Management (EM)

    May 17, 2011. Note: The following references, annotated in DOE O 440.1B, may be required to answer questions in the practice and criterion test for this module. 10 CFR 851, "Worker ...

  12. Cast polycrystalline silicon photovoltaic cell and module manufacturing technology improvements. Annual subcontract report, 1 December 1993--30 November 1994

    SciTech Connect (OSTI)

    Wohlgemuth, J.

    1995-09-01

    This report describes work performed under a 3-y contract to advance Solarex`s cast polycrystalline silicon manufacturing technology, reduce module production cost, increase module performance, and expand Solarex`s commercial production capacities. Specific objectives are to reduce manufacturing cost for polycrstalline silicon PV modules to less than $1.20/W and to increase manufacturing capacity by a factor of 3. Solarex is working on casting, wire saws, cell process, module assembly, frameless module development, and automated cell handling.

  13. UNITED STATES DEPARTMENT OF ENERGY (US DOE) DATA PRIVACY AND THE SMART GRID: A VOLUNTARY CODE OF CONDUCT (VCC)

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    DEPARTMENT OF ENERGY (US DOE) DATA PRIVACY AND THE SMART GRID: A VOLUNTARY CODE OF CONDUCT (VCC) Draft: 8/12/2014 MISSION STATEMENT The purpose of the Privacy Voluntary Code of Conduct, facilitated by the United States Department of Energy's Office of Electricity Delivery and Energy Reliability and the Federal Smart Grid Task Force, is to describe principles for voluntary adoption that: (1) encourage innovation while appropriately protecting the privacy and confidentiality of Customer Data and

  14. Microsoft Word - BPD Privacy Terms

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Data Privacy Terms (Updated 2014-12) Your company or organization (PROVIDER) has agreed to provide PROPRIETARY DATA regarding building energy performance to the Buildings Performance Database project that the Department of Energy (the Government) and its Laboratories (collectively referred to herein as the RECIPIENT) will use in its research. PROPRIETARY DATA is defined as follows: (a) DATA that embody trade secrets or are commercial or financial information that is confidential and privileged;

  15. DOE Order Self Study Modules - DOE O 151.1C Comprehensive Emergency Management System

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    O 151.1C COMPREHENSIVE EMERGENCY MANAGEMENT SYSTEM NATIONAL NUCLEAR SECURITY ADMINISTRATION SERVICE CENTER Change No: 3 DOE O 151.1C Level: Familiar Date: 12/1/08 1 DOE O 151.1C COMPREHENSIVE EMERGENCY MANAGEMENT SYSTEM FAMILIAR LEVEL _________________________________________________________________________ OBJECTIVES Given the familiar level of this module and the resources listed below, you will be able to: 1. List the objectives of DOE O 151.1C, Comprehensive Emergency Management System

  16. Privacy Act Officers Contact List | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Privacy Act Officers Contact List Privacy Act Officers Contact List Privacy Act Officers Contact List.docx (20.94 KB) More Documents & Publications Technical Standards Managers Contact List DOE-TSL-2-2002 VPP POINTS OF CONTACT

  17. Freedom of Information and Privacy Act - Hanford Site

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Act Freedom of Information and Privacy Act DOE Headquarters FOIA Web Page A Citizen's Guide to the FOIA and Privacy Act Making a Privacy Act Request Freedom of Information Act, 5...

  18. Waste Receiving and Processing Facility Module 1: Volume 1, Preliminary Design report

    SciTech Connect (OSTI)

    Not Available

    1992-03-01

    The Preliminary Design Report (Title 1) for the Waste Receiving and Processing (WRAP) Module 1 provides a comprehensive narrative description of the proposed facility and process systems, the basis for each of the systems design, and the engineering assessments that were performed to support the technical basis of the Title 1 design. The primary mission of the WRAP 1 Facility is to characterize and certify contact-handled (CH) waste in 55-gallon drums for disposal. Its secondary function is to certify CH waste in Standard Waste Boxes (SWBs) for disposal. The preferred plan consist of retrieving the waste and repackaging as necessary in the Waste Receiving and Processing (WRAP) facility to certify TRU waste for shipment to the Waste Isolation Pilot Plant (WIPP) in New Mexico. WIPP is a research and development facility designed to demonstrate the safe and environmentally acceptable disposal of TRU waste from National Defense programs. Retrieved waste found to be Low-Level Waste (LLW) after examination in the WRAP facility will be disposed of on the Hanford site in the low-level waste burial ground. The Hanford Site TRU waste will be shipped to the WIPP for disposal between 1999 and 2013.

  19. Order Module--DOE O 425.1D, VERIFICATION OF READINESS TO START UP OR

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    RESTART NUCLEAR FACILITIES | Department of Energy 5.1D, VERIFICATION OF READINESS TO START UP OR RESTART NUCLEAR FACILITIES Order Module--DOE O 425.1D, VERIFICATION OF READINESS TO START UP OR RESTART NUCLEAR FACILITIES "The familiar level of this module is divided into three sections. In the first section we will discuss the purpose of DOE O 425.1D and the requirements for 1) determining the level of readiness review (RR), 2) determining the startup authorization authority (SAA), and

  20. Order Module--DOE O 451.1B, NATIONAL ENVIRONMENTAL POLICY ACT COMPLIANCE PROGRAM

    Broader source: Energy.gov [DOE]

    DOE O 451.1B, National Environmental Policy Act Compliance Program, replacesDOE O 451.1A of the same name. DOE O 451.1B is ten pages long. Due to the concise nature of this Order, this module...

  1. DOE Order Self Study Modules - DOE O 435.1 Radioactive Waste Management

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    5.1 RADIOACTIVE WASTE MANAGEMENT ALBUQUERQUE OPERATIONS OFFICE Change No: 0 DOE O 435.1 Level: Familiar Date: 6/15/01 1 DOE O 435.1 RADIOACTIVE WASTE MANAGEMENT FAMILIAR LEVEL _________________________________________________________________________ OBJECTIVES Given the familiar level of this module and the resources listed below, you will be able to 1. Discuss the purpose and scope of DOE O 435.1, Radioactive Waste Management. Note: If you think that you can complete the practice at the end of

  2. Manager's Signature Log Privacy Impact Assessment, Office of...

    Office of Environmental Management (EM)

    Manager's Signature Log Privacy Impact Assessment, Office of Science Chicago Office Manager's Signature Log Privacy Impact Assessment, Office of Science Chicago Office Manager's ...

  3. DOE Convenes Multi-stakeholder Process to Address Privacy for...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Convenes Multi-stakeholder Process to Address Privacy for Data Enabled by Smart Grid Technologies DOE Convenes Multi-stakeholder Process to Address Privacy for Data Enabled by ...

  4. DOE - NNSA/NFO -- Disclaimer, Privacy and Security Notice

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Disclaimer, Privacy and Security Notice NNSANFO Language Options U.S. DOENNSA - Nevada Field Office Privacy and Security Notice Information from this server resides on a computer ...

  5. PII. DOE Order 206. I, Department of Energy Privacy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ... Vision Strengthen Privacy Protections by Building a Full Lifecycle, Integrated and Auditable Privacy Program that Preserves the Trust of the American People Employee Guide t o ...

  6. Department of Energy Data Access and Privacy Issues Related To...

    Office of Environmental Management (EM)

    Data Access and Privacy Issues Related To Smart Grid Technologies Department of Energy Data Access and Privacy Issues Related To Smart Grid Technologies This report by the ...

  7. NBP RFI: Data Access, Third Party Use, and Privacy- Comments...

    Office of Environmental Management (EM)

    Use, and Privacy- Comments of Oncor Electric Deliverty Company LLC NBP RFI: Data Access, ... NBP RFI: Data Access, Third Party Use, and Privacy- Comments of Oncor Electric Deliverty ...

  8. Public Roundtable- Data Access and Privacy Issues Related to...

    Energy Savers [EERE]

    Roundtable- Data Access and Privacy Issues Related to Smart Grid Technologies Public Roundtable- Data Access and Privacy Issues Related to Smart Grid Technologies Transcript of ...

  9. Waste receiving and processing facility module 1, detailed design report

    SciTech Connect (OSTI)

    Not Available

    1993-10-01

    WRAP 1 baseline documents which guided the technical development of the Title design included: (a) A/E Statement of Work (SOW) Revision 4C: This DOE-RL contractual document specified the workscope, deliverables, schedule, method of performance and reference criteria for the Title design preparation. (b) Functional Design Criteria (FDC) Revision 1: This DOE-RL technical criteria document specified the overall operational criteria for the facility. The document was a Revision 0 at the beginning of the design and advanced to Revision 1 during the tenure of the Title design. (c) Supplemental Design Requirements Document (SDRD) Revision 3: This baseline criteria document prepared by WHC for DOE-RL augments the FDC by providing further definition of the process, operational safety, and facility requirements to the A/E for guidance in preparing the design. The document was at a very preliminary stage at the onset of Title design and was revised in concert with the results of the engineering studies that were performed to resolve the numerous technical issues that the project faced when Title I was initiated, as well as, by requirements established during the course of the Title II design.

  10. DOE Order Self Study Modules - DOE O 442.1 Department of energy Employee Concerns Program

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    42.1 DEPARTMENT OF ENERGY EMPLOYEE CONCERNS PROGRAM ALBUQUERQUE OPERATIONS OFFICE Change No: 0 DOE O 442.1 Level: Familiar Date: 6/15/01 1 DOE O 442.1 DOE EMPLOYEE CONCERNS PROGRAM FAMILIAR LEVEL _________________________________________________________________________ OBJECTIVES Given the familiar level of this module and the resources listed below, you will be able to perform the following: 1. State three examples of criteria that should be used to assess the significance of an employee's

  11. December 11 Webinar on Smart Grid Data Privacy: A Voluntary Code of Conduct

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    | Department of Energy December 11 Webinar on Smart Grid Data Privacy: A Voluntary Code of Conduct December 11 Webinar on Smart Grid Data Privacy: A Voluntary Code of Conduct November 20, 2014 - 9:12am Addthis On Thursday, December 11, 2014, from 1 - 4 p.m. ET, the Office of Electricity Delivery and Energy Reliability (OE) in coordination with the Federal Smart Grid Task Force will conduct a webinar to conclude the development phase of a Voluntary Code of Conduct (VCC) related to privacy of

  12. Data Privacy Policy

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Career Opportunities ESnet Staff & Org Chart Contact Us Contact Us Technical Assistance: 1 ... Report Network Problems: trouble@es.net Provide Web Site Feedback: info@es.net Data ...

  13. Order Module--DOE O 458.1, RADIATION PROTECTION OF THE PUBLIC AND THE

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ENVIRONMENT | Department of Energy 58.1, RADIATION PROTECTION OF THE PUBLIC AND THE ENVIRONMENT Order Module--DOE O 458.1, RADIATION PROTECTION OF THE PUBLIC AND THE ENVIRONMENT The familiar level of this module is divided into two sections. In the first section, we will discuss the objectives and definitions related to the Order. In the second section, we will discuss the requirements in section four of the Order and the responsibilities of the field element managers for compliance with DOE

  14. Numerical study of self modulation instability of 1 nC electron bunch at ATF

    SciTech Connect (OSTI)

    Fang Yun; Mori, Warren; Muggli, Patric

    2012-12-21

    The development of self-modulation instability (SMI) is investigated numerically for the 1 nC electron bunch available at Accelerator Test Facility (ATF) of Brookhaven National Laboratory (BNL). Possible experiment based on the simulation results is proposed. All the simulations are performed with the 2D-cylindrically symmetric particle-in-cell code.

  15. Waste Receiving and Processing Facility Module 1 Data Management System Software Requirements Specification

    SciTech Connect (OSTI)

    Brann, E.C. II

    1994-09-09

    This document provides the software requirements for Waste Receiving and Processing (WRAP) Module 1 Data Management System (DMS). The DMS is one of the plant computer systems for the new WRAP 1 facility (Project W-026). The DMS will collect, store and report data required to certify the low level waste (LLW) and transuranic (TRU) waste items processed at WRAP 1 as acceptable for shipment, storage, or disposal.

  16. Order Module--DOE Order 422.1, CONDUCT OF OPERATIONS | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Order 422.1, CONDUCT OF OPERATIONS Order Module--DOE Order 422.1, CONDUCT OF OPERATIONS The general approach to implementing DOE O 422.1 is for contractors to develop, for DOE line management approval, documentation demonstrating implementation of the requirements in the contractor requirements document (CRD). DOE line management means the Federal officials such as Secretarial Officers and heads of field elements responsible for DOE facilities and operations. It is necessary to provide a conduct

  17. Development of flame retardant PV module encapsulants: Volume 1. Final report

    SciTech Connect (OSTI)

    Galica, J.P.

    1998-06-01

    This Phase 1 final report covers the work performed by Springborn Testing and Research, Inc., for the period October 1, 1997 to June 30, 1998 under the Department of Energy Cooperative Agreement Number DE-FC36-97GO10255, entitled Development of Flame Retardant PV Module Encapsulants. While use of roof-mounted arrays has always been an attractive means of deploying PV, only within recent years have such building integrated concepts (BIPV) found renewed interest among module makers and end-users. Prior to building integrated and rooftop applications, flammability requirements for modules have not been a great industry concern. However, with growing interest in BIPV and the requirement for building code requirements for commercial and industrial structures, flammability issues have become a barrier to entry for many module constructions into this potentially huge domestic market for PV. The overall goal of the 3 phase PV BONUS two project is to develop and commercialize a line of fire retardant encapsulation materials to serve the emerging building integrated and building mounted PV market. The objectives of the Phase 1 effort are limited to concept development and business planning activities.

  18. DEPARTMENT OF ENERGY Privacy Awareness Training | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    DEPARTMENT OF ENERGY Privacy Awareness Training DEPARTMENT OF ENERGY Privacy Awareness Training DEPARTMENT OF ENERGY Privacy Awareness Training DEPARTMENT OF ENERGY Privacy Awareness Training (440.3 KB) More Documents & Publications PIA - INL SECURITY INFORMATION MANAGEMENT SYSTEM BUSINESS ENCLAVE LM Records Handling System (LMRHS01) - Electronic Records Keeping System, Office of Legacy Management, LM Records Handling System-Freedom of Information/Privacy Act, Office of Legacy managemen

  19. Order Module--DOE O 414.1D, QUALITY ASSURANCE | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    14.1D, QUALITY ASSURANCE Order Module--DOE O 414.1D, QUALITY ASSURANCE "To ensure that DOE, including NNSA, products and services meet or exceed customers' requirements and expectations. To achieve quality for all work based upon the following principles: All work, as defined in this Order, is conducted through an integrated and effective management system. Management support for planning, organization, resources, direction, and control is essential to quality assurance (QA). Performance

  20. A Generic Biogeochemical Module for Earth System Models: Next Generation BioGeoChemical Module (NGBGC), Version 1.0

    SciTech Connect (OSTI)

    Fang, Yilin; Huang, Maoyi; Liu, Chongxuan; Li, Hongyi; Leung, Lai-Yung R.

    2013-11-13

    Physical and biogeochemical processes regulate soil carbon dynamics and CO2 flux to and from atmosphere, influencing global climate changes. Integration of these processes into earth system models (e.g., community land models (CLM)), however, currently faces three major challenges: 1) extensive efforts are required to modify modeling structures and to rewrite computer programs to incorporate new or updated processes as new knowledge is being generated, 2) computational cost is prohibitively expensive to simulate biogeochemical processes in land models due to large variations in the rates of biogeochemical processes, and 3) various mathematical representations of biogeochemical processes exist to incorporate different aspects of fundamental mechanisms, but systematic evaluation of the different mathematical representations is difficult, if not possible. To address these challenges, we propose a new computational framework to easily incorporate physical and biogeochemical processes into land models. The new framework consists of a new biogeochemical module with a generic algorithm and reaction database so that new and updated processes can be incorporated into land models without the need to manually set up the ordinary differential equations to be solved numerically. The reaction database consists of processes of nutrient flow through the terrestrial ecosystems in plants, litter and soil. This framework facilitates effective comparison studies of biogeochemical cycles in an ecosystem using different conceptual models under the same land modeling framework. The approach was first implemented in CLM and benchmarked against simulations from the original CLM-CN code. A case study was then provided to demonstrate the advantages of using the new approach to incorporate a phosphorus cycle into the CLM model. To our knowledge, the phosphorus-incorporated CLM is a new model that can be used to simulate phosphorus limitation on the productivity of terrestrial ecosystems.

  1. Points of Contact and Privacy Act Advisory

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Points of Contact Points of Contact and Privacy Act Advisory If you are trying to contact an agency other than the Department of Energy, use the web address: http:...

  2. Privacy and Security Notice | Jefferson Lab

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Privacy and Security Notice Security Notice This is a Federal computer system and is the property of the U.S. Government. It is for authorized use only. Users (authorized or unauthorized) have no explicit or implicit expectation of privacy. Any or all uses of this system, associated connected systems and all files may be intercepted, monitored, recorded, copied, audited, inspected, and disclosed to authorized site, Department of Energy, and law enforcement personnel, as well as authorized

  3. GridLAB-D Technical Support Document: Residential End-Use Module Version 1.0

    SciTech Connect (OSTI)

    Taylor, Zachary T.; Gowri, Krishnan; Katipamula, Srinivas

    2008-07-31

    1.0 Introduction The residential module implements the following end uses and characteristics to simulate the power demand in a single family home: • Water heater • Lights • Dishwasher • Range • Microwave • Refrigerator • Internal gains (plug loads) • House (heating/cooling loads) The house model considers the following four major heat gains/losses that contribute to the building heating/cooling load: 1. Conduction through exterior walls, roof and fenestration (based on envelope UA) 2. Air infiltration (based on specified air change rate) 3. Solar radiation (based on CLTD model and using tmy data) 4. Internal gains from lighting, people, equipment and other end use objects. The Equivalent Thermal Parameter (ETP) approach is used to model the residential loads and energy consumption. The following sections describe the modeling assumptions for each of the above end uses and the details of power demand calculations in the residential module.

  4. The Engineering Design of the 1.5 m Diameter Solenoid for the MICERFCC Modules

    SciTech Connect (OSTI)

    Wang, L.; Green, M.A.; Xu, F.Y.; Wu, H.; Li, L.K.; Gou, C.S.; Liu, C.S.; Han, G.; Jia, L.X.; Li, D.; Prestemon, S.O.; Virostek, S.P.

    2007-08-27

    The RF coupling coil (RFCC) module of MICE is where muonsthat have been cooled within the MICE absorber focus (AFC) modules arere-accelerated to their original longitudinal momentum. The RFCC moduleconsists of four 201.25 MHz RF cavities in a 1.4 meter diameter vacuumvessel. The muons are kept within the RF cavities by the magnetic fieldgenerated by a superconducting coupling solenoid that goes around the RFcavities. The coupling solenoid will be cooled using a pair of 4 K pulsetube cooler that will generate 1.5 W of cooling at 4.2 K. The magnet willbe powered using a 300 A two-quadrant power supply. This report describesthe ICST engineering design of the coupling solenoid forMICE.

  5. Order Module--DOE O 430.1B, REAL PROPERTY ASSET MANAGEMENT | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy 30.1B, REAL PROPERTY ASSET MANAGEMENT Order Module--DOE O 430.1B, REAL PROPERTY ASSET MANAGEMENT "The objective of DOE O 430.1B, Real Property Asset Management, is to establish a corporate, holistic, and performance-based approach to real property life-cycle asset management that links real property asset planning, programming, budgeting, and evaluation to program mission projections and performance outcomes. To accomplish the objective, this Order identifies requirements and

  6. Protocatechuic aldehyde ameliorates experimental pulmonary fibrosis by modulating HMGB1/RAGE pathway

    SciTech Connect (OSTI)

    Zhang, Liang Ji, Yunxia Kang, Zechun Lv, Changjun Jiang, Wanglin

    2015-02-15

    An abnormal high mobility group box 1 (HMGB1) activation and a decrease in receptor for advanced glycation end-product (RAGE) play a key role in the pathogenesis of pulmonary fibrosis. Protocatechuic aldehyde (PA) is a naturally occurring compound, which is extracted from the degradation of phenolic acids. However, whether PA has anti-fibrotic functions is unknown. In this study, the effects of PA on the transforming growth factor-β1 (TGF-β1)-mediated epithelial–mesenchymal transition (EMT) in A549 cells, on the apoptosis of human type I alveolar epithelial cells (AT I), on the proliferation of human lung fibroblasts (HLF-1) in vitro, and on bleomycin (BLM)-induced pulmonary fibrosis in vivo were investigated. PA treatment resulted in a reduction of EMT in A549 cells with a decrease in vimentin and HMGB, an increase of E-cadherin and RAGE, a reduction of HLF-1 proliferation with a decrease of fibroblast growth factor 2 (FGF-2) and platelet-derived growth factor (PDGF). Apoptosis of AT I was attenuated with an increase of RAGE. PA ameliorated BLM-induced pulmonary fibrosis in rats with a reduction of histopathological scores and collagen deposition, and a lower FGF-2, PDGF, α-smooth muscle actin (α-SMA) and HMGB1 expression, whereas higher RAGE was found in BLM-instilled lungs. Through the decrease of HGMB1 and the regulation of RAGE, PA reversed the EMT, inhibited HLF-1 proliferation as well as reduced apoptosis in AT I, and prevented pulmonary fibrosis in vivo. Collectively, our results demonstrate that PA prevents experimental pulmonary fibrosis by modulating HMGB1/RAGE pathway. - Highlights: • PA prevents EMT, reduces the apoptosis of AT1 in vitro. • PA decreases proliferation of HLF-1, reduces PDGF and FGF expression in vitro. • PA prevents experimental pulmonary fibrosis by modulating the HMGB1/RAGE pathway.

  7. Manager's Signature Log Privacy Impact Assessment, Office of Science

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Chicago Office | Department of Energy Manager's Signature Log Privacy Impact Assessment, Office of Science Chicago Office Manager's Signature Log Privacy Impact Assessment, Office of Science Chicago Office Manager's Signature Log Privacy Impact Assessment, Office of Science Chicago Office Manager's Signature Log Privacy Impact Assessment, Office of Science Chicago Office (110.12 KB) More Documents & Publications Integrated Safety Management Workshop Registration, PIA, Idaho National

  8. Freedom of Information and Privacy Act Database PIA, Idaho Operations

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Office | Department of Energy Information and Privacy Act Database PIA, Idaho Operations Office Freedom of Information and Privacy Act Database PIA, Idaho Operations Office Freedom of Information and Privacy Act Database PIA, Idaho Operations Office Freedom of Information and Privacy Act Database PIA, Idaho Operations Office (170.34 KB) More Documents & Publications PIA - Security Clearance Work Tracking and Budget System TRAIN-PIA.pdf Occupational Medicine - Assistant PIA, Idaho

  9. The Genetic Privacy Act and commentary

    SciTech Connect (OSTI)

    Annas, G.J.; Glantz, L.H.; Roche, P.A.

    1995-02-28

    The Genetic Privacy Act is a proposal for federal legislation. The Act is based on the premise that genetic information is different from other types of personal information in ways that require special protection. Therefore, to effectively protect genetic privacy unauthorized collection and analysis of individually identifiable DNA must be prohibited. As a result, the premise of the Act is that no stranger should have or control identifiable DNA samples or genetic information about an individual unless that individual specifically authorizes the collection of DNA samples for the purpose of genetic analysis, authorized the creation of that private information, and has access to and control over the dissemination of that information.

  10. MODULATION OF GALACTIC COSMIC RAYS OBSERVED AT L1 IN SOLAR CYCLE 23

    SciTech Connect (OSTI)

    Fludra, A.

    2015-01-20

    We analyze a unique 15yr record of galactic cosmic-ray (GCR) measurements made by the SOHO Coronal Diagnostic Spectrometer NIS detectors, recording integrated GCR numbers with energies above 1.0GeV between 1996 July and 2011 June. We are able to closely reproduce the main features of the SOHO/CDS GCR record using the modulation potential calculated from neutron monitor data by Usoskin etal. The GCR numbers show a clear solar cycle modulation: they decrease by 50% from the 1997 minimum to the 2000 maximum of the solar cycle, then return to the 1997 level in 2007 and continue to rise, in 2009 December reaching a level 25% higher than in 1997. This 25% increase is in contrast with the behavior of Ulysses/KET GCR protons extrapolated to 1 AU in the ecliptic plane, showing the same level in 2008-2009 as in 1997. The GCR numbers are inversely correlated with the tilt angle of the heliospheric current sheet. In particular, the continued increase of SOHO/CDS GCRs from 2007 until 2009 is correlated with the decrease of the minimum tilt angle from 30 in mid-2008 to 5 in late 2009. The GCR level then drops sharply from 2010 January, again consistent with a rapid increase of the tilt angle to over 35. This shows that the extended 2008 solar minimum was different from the 1997 minimum in terms of the structure of the heliospheric current sheet.

  11. A 1 MEGAWATT POLYPHASE BOOST CONVERTER-MODULATOR FOR KLYSTRON PULSE APPLICATION

    SciTech Connect (OSTI)

    W.A. REASS; J.D. DOSS; R.F. GRIBBLE

    2001-06-01

    This paper describes electrical design criteria and first operational results a 140 kV, 1 MW average, 11 MW peak, zero-voltage-switching 20 kHz polyphase bridge, boost converter/modulator for klystron pulse application. The DC-DC converter derives the buss voltages from a standard 13.8 kV to 2300 Y substation cast-core transformer. Energy storage and filtering is provided by self-clearing metallized hazy polypropylene traction capacitors. Three ''H-Bridge'' Insulated Gate Bipolar Transistor (IGBT) switching networks are used to generate the polyphase 20 kHz transformer primary drive waveforms. The 20 kHz drive waveforms are chirped the appropriate duration to generate the desired klystron pulse width. PWM (pulse width modulation) of the individual 20 kHz pulses is utilized to provide regulated output waveforms with adaptive feedforward and feedback techniques. The boost transformer design utilizes amorphous nanocrystalline material that provides the required low core loss at design flux levels and switching frequencies. Resonant shunt-peaking is used on the transformer secondary to boost output voltage and resonate transformer leakage inductance. With the appropriate transformer leakage inductance and peaking capacitance, zero-voltage-switching of the IGBT's is attained, minimizing switching losses. A review of these design parameters and the first results of the performance characteristics will be presented.

  12. Year Modules

    U.S. Energy Information Administration (EIA) Indexed Site

    dollars per peak watt) Year Modules 2004 $2.99 2005 $3.19 2006 $3.50 2007 $3.37 2008 $3.49 2009 $2.79 2010 $1.96 2011 $1.59 2012 $1.15 2013 $0.75 2014 $0.87 Table 4. Average value of photovoltaic modules, 2004-2014 Source: U.S. Energy Information Administration, Form EIA-63B, 'Annual Photovoltaic Cell/Module Shipments Report.' Note: Dollars are not adjusted for inflation.

  13. Waste Receiving and Processing Facility Module 2A: Advanced Conceptual Design Report. Volume 1

    SciTech Connect (OSTI)

    Not Available

    1994-03-01

    This ACDR was performed following completed of the Conceptual Design Report in July 1992; the work encompassed August 1992 to January 1994. Mission of the WRAP Module 2A facility is to receive, process, package, certify, and ship for permanent burial at the Hanford site disposal facilities the Category 1 and 3 contact handled low-level radioactive mixed wastes that are currently in retrievable storage at Hanford and are forecast to be generated over the next 30 years by Hanford, and waste to be shipped to Hanford from about DOE sites. This volume provides an introduction to the ACDR process and the scope of the task along with a project summary of the facility, treatment technologies, cost, and schedule. Major areas of departure from the CDR are highlighted. Descriptions of the facility layout and operations are included.

  14. MNK1 expression increases during cellular senescence and modulates the subcellular localization of hnRNP A1

    SciTech Connect (OSTI)

    Ziaei, Samira; The Graduate School and University Center of CUNY, New York, NY ; Shimada, Naoko; Kucharavy, Herman; Hubbard, Karen; The Graduate School and University Center of CUNY, New York, NY

    2012-03-10

    Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is an RNA-binding protein that modulates splice site usage, polyadenylation, and cleavage efficiency. This protein has also been implicated in mRNA stability and transport from the nucleus. We have previously demonstrated that hnRNP A1 had diminished protein levels and showed cytoplasmic accumulation in senescent human diploid fibroblasts. Furthermore, we have shown that inhibition of p38 MAPK, a key regulator of cellular senescence, elevated hnRNP A1 protein levels and inhibited hnRNP A1 cytoplasmic localization. In this study, we have explored the possible involvement of MNK1, one of the downstream effector of p38 MAPK, in the regulation of hnRNP A1. We have demonstrated that pharmacological inhibition of MNK1 by CGP 57380 decreased the phosphorylation levels of hnRNP A1 in young and senescent fibroblast cells and blocked the cytoplasmic accumulation of hnRNP A1 in senescent cells. In addition, MNK1 formed a complex with hnRNP A1 in vivo. The expression levels of MNK1, phospho-MNK1, and phospho-eIF4E proteins were found to be elevated in senescent cells. These data suggest that MNK1 regulates the phosphorylation and the subcellular distribution of hnRNP A1 and that MNK1 may play a role in the induction of senescence. -- Highlights: Black-Right-Pointing-Pointer MNK1 and not MAPKAPK2 phosphorylates hnRNP A1. Black-Right-Pointing-Pointer MNK1 has elevated levels in senescent cells, this has not been reported previously. Black-Right-Pointing-Pointer MNK1 activity induces cytoplasmic accumulation of hnRNP A1 in senescent cells. Black-Right-Pointing-Pointer Altered cytoplasmic localization of hnRNP A1 may alter gene expression patterns. Black-Right-Pointing-Pointer Our studies may increase our understanding of RNA metabolism during cellular aging.

  15. PROPERTIES OF THE 24 DAY MODULATION IN GX 13+1 FROM NEAR-INFRARED AND X-RAY OBSERVATIONS

    SciTech Connect (OSTI)

    Corbet, Robin H. D.; Pearlman, Aaron B.; Buxton, Michelle; Levine, Alan M. E-mail: aaronp1@umbc.ed

    2010-08-10

    A 24 day period for the low-mass X-ray binary (LMXB) GX 13+1 was previously proposed on the basis of seven years of RXTE All-Sky Monitor (ASM) observations and it was suggested that this was the orbital period of the system. This would make it one of the longest known orbital periods for a Galactic LMXB powered by Roche lobe overflow. We present here the results of (1) K-band photometry obtained with the SMARTS Consortium CTIO 1.3 m telescope on 68 nights over a 10 month interval; (2) continued monitoring with the RXTE ASM, analyzed using a semi-weighted power spectrum instead of the data filtering technique previously used; and (3) Swift Burst Alert Telescope (BAT) hard X-ray observations. Modulation near 24 days is seen in both the K band and additional statistically independent ASM X-ray observations. However, the modulation in the ASM is not strictly periodic. The periodicity is also not detected in the Swift BAT observations, but modulation at the same relative level as seen with the ASM cannot be ruled out. If the 24 day period is the orbital period of system, this implies that the X-ray modulation is caused by structure that is not fixed in location. A possible mechanism for the X-ray modulation is the dipping behavior recently reported from XMM-Newton observations.

  16. Year Modules

    U.S. Energy Information Administration (EIA) Indexed Site

    Annual photovoltaic module shipments, 2004-2014 (peak kilowatts) Year Modules 2004 143,274 2005 204,996 2006 320,208 2007 494,148 2008 920,693 2009 1,188,879 2010 2,644,498 2011 3,772,075 2012 4,655,005 2013 4,984,881 2014 6,237,524 Source: U.S. Energy Information Administration, Form EIA-63B, 'Annual Photovoltaic Cell/Module Shipments Report.' Note: Includes both U.S. Shipments and Exports.

  17. Privacy Policy | Princeton Plasma Physics Lab

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Privacy Policy Security Notice The Princeton Plasma Physics Laboratory (PPPL) is operated by Princeton University for the United States Department of Energy (DOE). As such the following rules apply: This web site is part of a Federal computer system used to accomplish Federal functions. The Department of Energy monitors this web site for security purposes to ensure it remains available to all users and to protect information in the system. Users (authorized or unauthorized) have no explicit or

  18. Research on stable, high-efficiency amorphous silicon multijunction modules. Semiannual subcontract report, 1 March 1993--30 November 1993

    SciTech Connect (OSTI)

    Guha, S.

    1994-03-01

    This report describes the progress made during the first half of Phase III of the R&D program to obtain high-efficiency amorphous silicon alloy multijunction modules. The highlight of the work includes (1) demonstration of the world`s highest initial module efficiency (area of 0.09 m{sup 2}) of 11.4% as confirmed by NREL, and (2) demonstration of stable module efficiency of 9.5% after 1-sun light soaking for 1000 h at 50{degrees}C. In addition, fundamental studies were carried out to improve material properties of the component cells of the multijunction structure and to understand the optical losses associated with the back reflector.

  19. Medical information and the right to privacy

    SciTech Connect (OSTI)

    Drell, D.

    1994-06-01

    This report is a compilation of submitted abstracts of papers presented at the DOE-supported workshop on medical information and the right to privacy held at the National Academy of Sciences in Washington, DC, on June 9 and 10, 1994. The aim of this meeting is to provide a forum to discuss the legal, ethical and practical issues related to the computerization and use of medical data, as well as the potential impact the use of these data may have on an individual`s privacy. Topical areas include an overview of the Federal and legal requirements to collect medical data, historical experiences with worker screening programs, currently available medical surveillance technologies (both biomedical and computer technologies) and their limitations. In addition, an-depth assessment of the needs and interests of a wide spectrum of parties as they relate to the use of medical data from both a legal and privacy perspective is provided. The needs of the individual, the public (e.g., blood and tissue banks), private enterprises (e.g., industry and insurance carriers), and the government (e.g., FBI) are discussed. Finally, the practical and legal issues relating to the use of computers to carry, store and transmit this information are also examined. The abstracts are presented in the intended order of presentation as indicated in the agenda for the meeting.

  20. The Genetic Privacy Act and commentary

    SciTech Connect (OSTI)

    Annas, G.J.; Glantz, L.H.; Roche, P.A.

    1995-02-28

    The Genetic Privacy Act is a proposal for federal legislation. The Act is based on the premise that genetic information is different from other types of personal information in ways that require special protection. The DNA molecule holds an extensive amount of currently indecipherable information. The major goal of the Human Genome Project is to decipher this code so that the information it contains is accessible. The privacy question is, accessible to whom? The highly personal nature of the information contained in DNA can be illustrated by thinking of DNA as containing an individual`s {open_quotes}future diary.{close_quotes} A diary is perhaps the most personal and private document a person can create. It contains a person`s innermost thoughts and perceptions, and is usually hidden and locked to assure its secrecy. Diaries describe the past. The information in one`s genetic code can be thought of as a coded probabilistic future diary because it describes an important part of a unique and personal future. This document presents an introduction to the proposal for federal legislation `the Genetic Privacy Act`; a copy of the proposed act; and comment.

  1. U.S. DEPARTMENT OF ENERGY PRIVACY ACT INFORMATION REQUEST

    National Nuclear Security Administration (NNSA)

    PRIVACY ACT INFORMATION REQUEST (NOTE: Use of this form is recommended, but is not mandatory) To request Information or Action under the Act, complete appropriate Items in Part I. and establish identity in accordance with instructions on Reverse Side. Retain copy; submit original to the appropriate Privacy Act Officer at the U.S. Department of Energy Headquarters or Field location. Fax PA Form to 505-284-7512 Attention: Privacy Act Office NOTE: Records will be provided in CD format unless

  2. Privacy Act (PA) of 1974 | National Nuclear Security Administration |

    National Nuclear Security Administration (NNSA)

    (NNSA) Privacy Act (PA) of 1974 The purpose of the Privacy Act of 1974 (Act), Title 5, United States Code, Section 552a, is to balance the government's need to maintain information about individuals with the rights of individuals to be protected against unwarranted invasions of their privacy stemming from federal agencies' collection, maintenance, use, and disclosure of personal information about them. Therefore, unlike the Freedom of Information Act, the Act is not a disclosure Act and is

  3. U.S. DEPARTMENT OF ENERGY PRIVACY ACT INFORMATION REQUEST

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    PRIVACY ACT INFORMATION REQUEST (NOTE: Use of this form is recommended, but is not mandatory) To request Information or Action under the Act, complete appropriate Items in Part I. and establish identity in accordance with instructions on Reverse Side. Retain copy; submit original to the appropriate Privacy Act Officer at the U.S. Department of Energy Headquarters or Field location. . Fax PA Form to 202-586-8151 Attention: Privacy Act Office. NOTE: Records will be provided in CD format unless

  4. Privacy Impact Assessment | OSTI, US Dept of Energy Office of...

    Office of Scientific and Technical Information (OSTI)

    Privacy Impact Assessment Name of Project: Web Domains Maintained by the Office of Scientific and Technical Information (OSTI) Bureau: U.S. Department of Energy, Office of Science ...

  5. Freedom of Information and Privacy Act - Hanford Site

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    ... information). Please provide your specific justification for expedited processing: Make FOIA Request Contact Info and Privacy Act Advisory Share on Last Updated 08142016 9:52

  6. U.S. DEPARTMENT OF ENERGY PRIVACY ACT INFORMATION REQUEST

    National Nuclear Security Administration (NNSA)

    Privacy Act Officer at the U.S. Department of Energy Headquarters or Field location. ... Copy Distribution: Requester keeps copy; sends original to the Department of Energy . ...

  7. FOIA & PRIVACY ACT Appeal Information | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    FOIA & PRIVACY ACT Appeal Information FOIA & PRIVACY ACT Appeal Information The Freedom of Information Act, 5 U.S.C. § 552, and the Privacy Act, 5 U.S.C. § 552a, together contain the general principles under which executive agencies, such as the Department of Energy, make information in their possession available to the public and at the same time protect the privacy interest of individuals about whom the agency has obtained information. Each of these statutes requires the agencies to

  8. Carousel Trackers with 1-Sun or 3-Sun Modules for Commercial Building Rooftops

    SciTech Connect (OSTI)

    Gehl, Anthony C; Maxey, L Curt; Fraas, Dr. Lewis; Avery, James E.; Minkin, Leonid M; Huang, H,

    2008-01-01

    The goal is lower cost solar electricity. Herein, two evolutional steps are described toward achieving this goal. The first step is to follow the sun with a solar tracker. Herein, a carousel tracker is described for mounting on commercial building flat rooftops in order to produce more kWh per kW relative to fixed PV modules. The second evolutionary improvement is to produce lower cost 3-sun CPV modules where two thirds of the expensive single crystal silicon material is replaced by less expensive mirror material. This paper describes the performance and durability of two prototype installations demonstrating these evolutionary innovations. In the first case, the installation and operation of 2 carousels equipped with traditional flat plate modules is described. In the second case, the operation of a carousel equipped with new 3-sun CPV modules is described. Both systems have been operating as expected for several months through the winter of 2007.

  9. Computational Investigation of Glycosylation Effects on a Family 1 Carbohydrate-Binding Module

    SciTech Connect (OSTI)

    Taylor, C. B.; Talib, M. F.; McCabe, C.; Bu, L.; Adney, W. S.; Himmel, M. E.; Crowley, M. F.; Beckham, G. T.

    2012-01-27

    Carbohydrate-binding modules (CBMs) are ubiquitous components of glycoside hydrolases, which degrade polysaccharides in nature. CBMs target specific polysaccharides, and CBM binding affinity to cellulose is known to be proportional to cellulase activity, such that increasing binding affinity is an important component of performance improvement. To ascertain the impact of protein and glycan engineering on CBM binding, we use molecular simulation to quantify cellulose binding of a natively glycosylated Family 1 CBM. To validate our approach, we first examine aromatic-carbohydrate interactions on binding, and our predictions are consistent with previous experiments, showing that a tyrosine to tryptophan mutation yields a 2-fold improvement in binding affinity. We then demonstrate that enhanced binding of 3-6-fold over a nonglycosylated CBM is achieved by the addition of a single, native mannose or a mannose dimer, respectively, which has not been considered previously. Furthermore, we show that the addition of a single, artificial glycan on the anterior of the CBM, with the native, posterior glycans also present, can have a dramatic impact on binding affinity in our model, increasing it up to 140-fold relative to the nonglycosylated CBM. These results suggest new directions in protein engineering, in that modifying glycosylation patterns via heterologous expression, manipulation of culture conditions, or introduction of artificial glycosylation sites, can alter CBM binding affinity to carbohydrates and may thus be a general strategy to enhance cellulase performance. Our results also suggest that CBM binding studies should consider the effects of glycosylation on binding and function.

  10. LM Records Handling System-Freedom of Information/Privacy Act...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Freedom of InformationPrivacy Act, Office of Legacy management LM Records Handling System-Freedom of InformationPrivacy Act, Office of Legacy management LM Records Handling ...

  11. Data Privacy and the Smart Grid: A Voluntary Code of Conduct...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Conduct Data Privacy and the Smart Grid: A Voluntary Code of Conduct The Office of ... use services that addresses privacy related to data enabled by smart grid technologies. ...

  12. NBP RFI: Data Access, Third Party Use and Privacy- Comments of...

    Office of Environmental Management (EM)

    Use and Privacy- Comments of Baltimore Gas & Electric Company NBP RFI: Data Access, Third ... Empowering Customers and the Smart Grid: Data Access, Third Party Use, and Privacy NBP ...

  13. Data Privacy and the Smart Grid: A Voluntary Code of Conduct...

    Broader source: Energy.gov (indexed) [DOE]

    which addresses data privacy surrounding smart grid technologies, for public comment. ... In addition, in February 2012, the White House released the report, Consumer Data Privacy ...

  14. NBP RFI: Data Access, Third Party Use and Privacy- Comments of...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Use and Privacy- Comments of Utilities Telecom Council NBP RFI: Data Access, Third Party ... of Energy (DOE) request for information on data access, third party use, and privacy. ...

  15. DOE Order Self Study Modules - DOE O 433.1B, Maintenance Management Program for DOE Nuclear Facilities

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    433.1B MAINTENANCE MANAGEMENT PROGRAM FOR DOE NUCLEAR FACILITIES DOE O 433.1B Familiar Level August 2011 1 DOE O 433.1B MAINTENANCE MANAGEMENT PROGRAM FOR DOE NUCLEAR FACILITIES FAMILIAR LEVEL OBJECTIVES Given the familiar level of this module and the resources, you will be able to answer the following questions: 1. What is the objective of DOE O 433.1B, Maintenance Management Program for DOE Nuclear Facilities? 2. What is the purpose for quantitative indicators in maintenance management? 3.

  16. DOE Order Self Study Modules - DOE G 450.4-1B Integrated Safety Management Systems Guide

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    G 450.4-1B INTEGRATED SAFETY MANAGEMENT SYSTEM GUIDE ALBUQUERQUE OPERATIONS OFFICE Change No: 0 DOE G 450.4-1B Level: Familiar Date: 6/15/01 1 DOE G 450.4-1B INTEGRATED SAFETY MANAGEMENT SYSTEM (ISMS) GUIDE FAMILIAR LEVEL _________________________________________________________________________ OBJECTIVES Given the familiar level of this module and the resources listed below, you will be able to: 1. State the purpose of DOE G 450.4, ISMS Guide. 2. State the objectives of DOE G 450.4, ISMS Guide.

  17. Thermionic modules

    DOE Patents [OSTI]

    King, Donald B.; Sadwick, Laurence P.; Wernsman, Bernard R.

    2002-06-18

    Modules of assembled microminiature thermionic converters (MTCs) having high energy-conversion efficiencies and variable operating temperatures manufactured using MEMS manufacturing techniques including chemical vapor deposition. The MTCs incorporate cathode to anode spacing of about 1 micron or less and use cathode and anode materials having work functions ranging from about 1 eV to about 3 eV. The MTCs also exhibit maximum efficiencies of just under 30%, and thousands of the devices and modules can be fabricated at modest costs.

  18. Operators Manual and Technical Reference for the Z-Beamlet Phase Modulation Failsafe System: Version 1.

    SciTech Connect (OSTI)

    Armstrong, Darrell J.

    2014-09-01

    The need for pulse energies exceeding 4 kJ and pulse lengths [?] 2 ns in Sandia's Z-Beamlet laser (ZBL) requires that the single-frequency spectrum of its fiber-laser master oscillator be converted to a phase modulated spectrum with a modulation in dex [?] 5. Because accidental injection of single-frequency light into ZBL could result i n damage to optical materials from transverse stimulated Brillouin scattering, the presence of phase modulated (PM) light must be monitored by a reliable failsafe system that can stop a las er shot within of a few 10's of ns following a failure of the PM system. This requirement is met by combining optical heterodyne detection with high-speed electronics to indicate the pres ence or absence of phase modulated light. The transition time for the failsafe signal resultin g from a sudden failure using this technique is approximately 35 ns. This is sufficiently short to safely stop a single-frequency laser pulse from leaving ZBL's regenerative amplifier with a n approximately 35 ns margin of safety. This manual and technical reference contains detai led instructions for daily use of the PM failsafe system and provides enough additional informat ion for its maintenance and repair.

  19. Hop/STI1 modulates retinal proliferation and cell death independent of PrP{sup C}

    SciTech Connect (OSTI)

    Arruda-Carvalho, Maithe; Njaine, Brian; Silveira, Mariana S.; Linden, Rafael; Chiarini, Luciana B. . E-mail: chiarini@biof.ufrj.br

    2007-09-21

    Hop/STI1 is a co-chaperone adaptor protein for Hsp70/Hsp90 complexes. Hop/STI1 is found extracellularly and modulates cell death and differentiation through interaction with the prion protein (PrP{sup C}). Here, we investigated the expression of hop/STI1 and its role upon cell proliferation and cell death in the developing retina. Hop/STI1 is more expressed in developing rat retina than in the mature tissue. Hop/STI1 blocks retinal cell death in the neuroblastic layer (NBL) in a PrP{sup C} dependent manner, but failed to protect ganglion cells against axotomy-induced cell death. An antibody raised against hop/STI1 ({alpha}-STI1) blocked both ganglion cell and NBL cell death independent of PrP{sup C}. cAMP/PKA, ERK, PI3K and PKC signaling pathways were not involved in these effects. Hop/STI1 treatment reduced proliferation, while {alpha}-STI1 increased proliferation in the developing retina, both independent of PrP{sup C}. We conclude that hop/STI1 can modulate both proliferation and cell death in the developing retina independent of PrP{sup C}.

  20. 3D Torus Routing Engine Module for OFA OpenSM v. 1.0

    Energy Science and Technology Software Center (OSTI)

    2009-11-12

    This OpenFabrics Alliance (OFA) OpenSM routing engine module provides credit-loop-free routing while supporting two quality of service (QoS) levels for an InfiniBand fabric with a 3D torus topology. In addition it is able to route around multiple failed fabric links or a single failed fabric switch without introducing credit loops, and without changing path Service Level (SL) values granted before the failure.This OFA OpenSM routing engine module improves the operational characteristics of a parallel computermore » built using an InfiniBand fabric with a 3D torus topology. By providing two QoS levels, it allows system administrators to prevent application interprocess communication and file system communication from impacting each other. By providing the capability to route traffic around failed fabric components, it enables repair of failed components without impacting jobs running on the computer system.« less

  1. SCALE: A modular code system for performing Standardized Computer Analyses for Licensing Evaluation. Volume 1, Part 2: Control modules S1--H1; Revision 5

    SciTech Connect (OSTI)

    1997-03-01

    SCALE--a modular code system for Standardized Computer Analyses Licensing Evaluation--has been developed by Oak Ridge National Laboratory at the request of the US Nuclear Regulatory Commission. The SCALE system utilizes well-established computer codes and methods within standard analysis sequences that (1) allow an input format designed for the occasional user and/or novice, (2) automated the data processing and coupling between modules, and (3) provide accurate and reliable results. System development has been directed at problem-dependent cross-section processing and analysis of criticality safety, shielding, heat transfer, and depletion/decay problems. Since the initial release of SCALE in 1980, the code system has been heavily used for evaluation of nuclear fuel facility and package designs. This revision documents Version 4.3 of the system.

  2. SCALE: A modular code system for performing standardized computer analyses for licensing evaluation. Control modules -- Volume 1, Revision 4

    SciTech Connect (OSTI)

    Landers, N.F.; Petrie, L.M.; Knight, J.R.

    1995-04-01

    SCALE--a modular code system for Standardized Computer Analyses Licensing Evaluation--has been developed by Oak Ridge National Laboratory at the request of the US Nuclear Regulatory Commission. The SCALE system utilizes well-established computer codes and methods within standard analysis sequences that (1) allow an input format designed for the occasional user and/or novice, (2) automate the data processing and coupling between modules, and (3) provide accurate and reliable results. System development has been directed at problem-dependent cross-section processing and analysis of criticality safety, shielding, heat transfer, and depletion/decay problems. Since the initial release of SCALE in 1980, the code system has been heavily used for evaluation of nuclear fuel facility and package designs. This revision documents Version 4.2 of the system. This manual is divided into three volumes: Volume 1--for the control module documentation, Volume 2--for the functional module documentation, and Volume 3 for the documentation of the data libraries and subroutine libraries.

  3. Fast modulations of pulsating proton aurora related to subpacket structures of Pc1 geomagnetic pulsations at subauroral latitudes

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Ozaki, M.; Shiokawa, K.; Miyoshi, Y.; Kataoka, R.; Yagitani, S.; Inoue, T.; Ebihara, Y.; Jun, C. -W; Nomura, R.; Sakaguchi, K.; et al

    2016-08-14

    To understand the role of electromagnetic ion cyclotron (EMIC) waves in determining the temporal features of pulsating proton aurora (PPA) via wave-particle interactions at subauroral latitudes, high-time-resolution (1/8 s) images of proton-induced N2>+ emissions were recorded using a new electron multiplying charge-coupled device camera, along with related Pc1 pulsations on the ground. The observed Pc1 pulsations consisted of successive rising-tone elements with a spacing for each element of 100 s and subpacket structures, which manifest as amplitude modulations with a period of a few tens of seconds. In accordance with the temporal features of the Pc1 pulsations, the auroral intensitymore » showed a similar repetition period of 100 s and an unpredicted fast modulation of a few tens of seconds. Furthermore, these results indicate that PPA is generated by pitch angle scattering, nonlinearly interacting with Pc1/EMIC waves at the magnetic equator.« less

  4. 2015 Privacy Awareness Course (PAC) Annual Training | Department...

    Broader source: Energy.gov (indexed) [DOE]

    28, 2015 6:00AM to 9:00PM MDT Course Title: 2015 Privacy Awareness Course (PAC) Annual Training (COURSE 2015PACAICCv2) Completion Date: September 28, 2015 Audience: Mandatory...

  5. Genetic secrets: Protecting privacy and confidentiality in the genetic era

    SciTech Connect (OSTI)

    Rothstein, M.A.

    1998-07-01

    Few developments are likely to affect human beings more profoundly in the long run than the discoveries resulting from advances in modern genetics. Although the developments in genetic technology promise to provide many additional benefits, their application to genetic screening poses ethical, social, and legal questions, many of which are rooted in issues of privacy and confidentiality. The ethical, practical, and legal ramifications of these and related questions are explored in depth. The broad range of topics includes: the privacy and confidentiality of genetic information; the challenges to privacy and confidentiality that may be projected to result from the emerging genetic technologies; the role of informed consent in protecting the confidentiality of genetic information in the clinical setting; the potential uses of genetic information by third parties; the implications of changes in the health care delivery system for privacy and confidentiality; relevant national and international developments in public policies, professional standards, and laws; recommendations; and the identification of research needs.

  6. Microsoft Word - Privacy_Contact_Listing_September_21_2010

    Energy Savers [EERE]

    Chief Privacy Officer Jerry Hanley U.S. Department of Energy 1000 Independence Avenue, SW Washington, DC 20585 jerry.hanley@hq.doe.gov Phone: (202) 586-0483 Fax: (202) 586-0575...

  7. Freedom of Information Act (FOIA) and Privacy Act Requests |...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    penalty in the Privacy Act for requesting or obtaining access to records under false pretenses, and 2) include a declaration that your statement is true and correct under penalty ...

  8. Toward protocols for quantum-ensured privacy and secure voting

    SciTech Connect (OSTI)

    Bonanome, Marianna; Buzek, Vladimir; Ziman, Mario; Hillery, Mark

    2011-08-15

    We present a number of schemes that use quantum mechanics to preserve privacy, in particular, we show that entangled quantum states can be useful in maintaining privacy. We further develop our original proposal [see M. Hillery, M. Ziman, V. Buzek, and M. Bielikova, Phys. Lett. A 349, 75 (2006)] for protecting privacy in voting, and examine its security under certain types of attacks, in particular dishonest voters and external eavesdroppers. A variation of these quantum-based schemes can be used for multiparty function evaluation. We consider functions corresponding to group multiplication of N group elements, with each element chosen by a different party. We show how quantum mechanics can be useful in maintaining the privacy of the choices group elements.

  9. Module process optimization and device efficiency improvement for stable, low-cost, large-area, cadmium telluride-based photovoltaic module production. Annual subcontract report, 1 July 1990--31 December 1991

    SciTech Connect (OSTI)

    Albright, S.P.; Ackerman, B.; Chamberlin, R.R.; Jordan, J.F.

    1992-04-01

    This report describes work under a three-year phased subcontract to develop CdS/CdTe devices and modules and to further improve the technology base at Photon Energy, Inc. (PEI) to better address the commercialization issues and objectives of the PEI and the US Department of Energy. During this reporting period we (1) achieved efficiencies of 12.7% on small area devices, (2) achieved 1-ft{sup 2} modules with over 8% aperture-area efficiency (and active area efficiencies up to {approximately}10%), (3) tested 4-ft{sup 2} modules at NREL at 23.1 (21.3) watts, normalized (6.3% efficiency), and (4) found no inherent stability problems with CdTe technology during life testing, at both NREL and PEI. 7 refs.

  10. Smart Grid Privacy Workshop Summary Report (January 2012)

    Office of Energy Efficiency and Renewable Energy (EERE)

    To provide a collaborative environment for a variety of stakeholders to express their thoughts, opinions, and perspectives on smart grid consumer data privacy, OE hosted the Smart Grid Privacy Workshop on January 31, 2012. More than 80 representatives from several stakeholder groups attended the meeting. Participants represented 16 utilities, 15 third-party vendors and carriers, 12 consumer advocate organizations, 3 state commissions, and 9 federal agencies.

  11. Privacy Act Links to Related Sites | National Nuclear Security

    National Nuclear Security Administration (NNSA)

    Administration | (NNSA) Links to Related Sites The Privacy Act of 1974 (Title 5, United States Code, Section 552a). The Federal Register is the official daily publication for Rules, Proposed Rules, and Notices of Federal agencies and organizations, as well as Executive Orders and other Presidential Documents. The Privacy Act Issuances Compilation contains descriptions of Federal agency systems of records maintained on individuals and rules agencies follow to assist individuals who request

  12. A Phase 1 Study of Everolimus + Weekly Cisplatin + Intensity Modulated Radiation Therapy in Head-and-Neck Cancer

    SciTech Connect (OSTI)

    Fury, Matthew G.; Lee, Nancy Y.; Sherman, Eric; Ho, Alan L.; Rao, Shyam; Heguy, Adriana; Shen, Ronglai; Korte, Susan; Lisa, Donna; Ganly, Ian; Patel, Snehal; Wong, Richard J.; Shaha, Ashok; Shah, Jatin; Haque, Sofia; Katabi, Nora; Pfister, David G.

    2013-11-01

    Purpose: Elevated expression of eukaryotic protein synthesis initiation factor 4E (eIF4E) in histologically cancer-free margins of resected head and neck squamous cell carcinomas (HNSCCs) is mediated by mammalian target of rapamycin complex 1 (mTORC1) and has been associated with increased risk of disease recurrence. Preclinically, inhibition of mTORC1 with everolimus sensitizes cancer cells to cisplatin and radiation. Methods and Materials: This was single-institution phase 1 study to establish the maximum tolerated dose of daily everolimus given with fixed dose cisplatin (30 mg/m{sup 2} weekly 6) and concurrent intensity modulated radiation therapy for patients with locally and/or regionally advanced head-and-neck cancer. The study had a standard 3 + 3 dose-escalation design. Results: Tumor primary sites were oral cavity (4), salivary gland (4), oropharynx (2), nasopharynx (1), scalp (1), and neck node with occult primary (1). In 4 of 4 cases in which resected HNSCC surgical pathology specimens were available for immunohistochemistry, elevated expression of eIF4E was observed in the cancer-free margins. The most common grade ?3 treatment-related adverse event was lymphopenia (92%), and dose-limiting toxicities (DLTs) were mucositis (n=2) and failure to thrive (n=1). With a median follow up of 19.4 months, 2 patients have experienced recurrent disease. The maximum tolerated dose was everolimus 5 mg/day. Conclusions: Head-and-neck cancer patients tolerated everolimus at therapeutic doses (5 mg/day) given with weekly cisplatin and intensity modulated radiation therapy. The regimen merits further evaluation, especially among patients who are status post resection of HNSCCs that harbor mTORC1-mediated activation of eIF4E in histologically negative surgical margins.

  13. DOE Order Self Study Modules - DOE O 451.1B National Environmental...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    ENVIRONMENTAL POLICY ACT COMPLIANCE PROGRAM ALBUQUERQUE OPERATIONS OFFICE Change No: 1 DOE O 451.1B Level: Familiar Date: 61501 1 DOE O 451.1B NATIONAL ENVIRONMENTAL POLICY ACT ...

  14. Order Module--DOE O 460.1C, PACKAGING AND TRANSPORTATION SAFETY, DOE O 460.2A, DEPARTMENTAL MATERIALS TRANSPORTATION AND PACKAGING MANAGEMENT

    Office of Energy Efficiency and Renewable Energy (EERE)

    "The familiar level of this module is divided into two sections. The objectives and requirements of DOE O 460.1C and DOE O 460.2A will be discussed in the first and second sections, respectively....

  15. SCALE: A modular code system for performing standardized computer analyses for licensing evaluation. Functional modules F1--F8 -- Volume 2, Part 1, Revision 4

    SciTech Connect (OSTI)

    Greene, N.M.; Petrie, L.M.; Westfall, R.M.; Bucholz, J.A.; Hermann, O.W.; Fraley, S.K.

    1995-04-01

    SCALE--a modular code system for Standardized Computer Analyses Licensing Evaluation--has been developed by Oak Ridge National Laboratory at the request of the US Nuclear Regulatory Commission. The SCALE system utilizes well-established computer codes and methods within standard analysis sequences that (1) allow an input format designed for the occasional user and/or novice, (2) automate the data processing and coupling between modules, and (3) provide accurate and reliable results. System development has been directed at problem-dependent cross-section processing and analysis of criticality safety, shielding, heat transfer, and depletion/decay problems. Since the initial release of SCALE in 1980, the code system has been heavily used for evaluation of nuclear fuel facility and package designs. This revision documents Version 4.2 of the system. The manual is divided into three volumes: Volume 1--for the control module documentation; Volume 2--for functional module documentation; and Volume 3--for documentation of the data libraries and subroutine libraries.

  16. Cast polycrystalline silicon photovoltaic module manufacturing technology improvements. Semiannual technical report, 1 January 1996--30 June 1996

    SciTech Connect (OSTI)

    Wohlgemuth, J.

    1997-01-01

    Two specific objectives of Solarex`s program are to reduce the manufacturing cost for polycrystalline silicon photovoltaic modules to less than $1.20/watt and to increase the manufacturing capacity by a factor of three. This report highlights accomplishments during the period of January 1 through June 30, 1996. Accomplishments include: began the conversion of production casting stations to increase ingot size; operated the wire saw in a production mode with higher yields and lower costs than achieved on the ID saws; developed and qualified a new wire guide coating material that doubles the wire guide lifetime and produces significantly less scatter in wafer thickness; completed a third pilot run of the cost-effective Al paste back-surface-field (BSF) process, verifying a 5% increase in cell efficiency and demonstrating the ability to process and handle the BSF paste cells; completed environmental qualification of modules using cells produced by an all-print metallization process; optimized the design of the 15.2-cm by 15.2-cm polycrystalline silicon solar cells; demonstrated the application of a high-efficiency process in making 15.2-cm by 15.2-cm solar cells; demonstrated that cell efficiency increases with decreasing wafer thickness for the Al paste BSF cells; qualified a vendor-supplied Tedlar/ethylene vinyl acetate (EVA) laminate to replace the combination of separate sheets of EVA and Tedlar backsheet; demonstrated the operation of a prototype unit to trim/lead attach/test modules; and demonstrated the operation of a wafer pull-down system for cassetting wet wafers.

  17. Pregnane and Xenobiotic Receptor gene expression in liver cells is modulated by Ets-1 in synchrony with transcription factors Pax5, LEF-1 and c-jun

    SciTech Connect (OSTI)

    Kumari, Sangeeta; Saradhi, Mallampati; Rana, Manjul; Chatterjee, Swagata; Aumercier, Marc; Mukhopadhyay, Gauranga; Tyagi, Rakesh K.

    2015-01-15

    Nuclear receptor PXR is predominantly expressed in liver and intestine. Expression of PXR is observed to be dysregulated in various metabolic disorders indicating its involvement in disease development. However, information available on mechanisms of PXR self-regulation is fragmentary. The present investigation identifies some of the regulatory elements responsible for its tight regulation and low cellular expression. Here, we report that the PXR-promoter is a target for some key transcription factors like PU.1/Ets-1, Pax5, LEF-1 and c-Jun. Interestingly, we observed that PXR-promoter responsiveness to Pax5, LEF-1 and c-Jun, is considerably enhanced by Ets transcription factors (PU.1 and Ets-1). Co-transfection of cells with Ets-1, LEF-1 and c-Jun increased PXR-promoter activity by 5-fold and also induced expression of endogenous human PXR. Site-directed mutagenesis and transfection studies revealed that two Ets binding sites and two of the three LEF binding sites in the PXR-promoter are functional and have a positive effect on PXR transcription. Results suggest that expression of Ets family members, in conjunction with Pax5, LEF-1 and c-Jun, lead to coordinated up-regulation of PXR gene transcription. Insights obtained on the regulation of PXR gene have relevance in offering important cues towards normal functioning as well as development of several metabolic disorders via PXR signaling. - Highlights: • The study identified cis-regulatory elements in the nuclear receptor PXR promoter. • Several trans-acting factors modulating the PXR-promoter have been identified. • PU.1/Ets-1, Pax5, LEF-1, c-Jun, LyF-VI and NF-1 act as modulators of the PXR-promoter. • Ets-1 in conjunction with LEF-1 and c-Jun exhibit 5-fold activation of the PXR-promoter. • Insights into PXR-regulation have relevance in normal and pathological conditions.

  18. Insights into Regulated Ligand Binding Sites from the Structure of ZO-1 Src Homology 3-Guanylate Kinase Module

    SciTech Connect (OSTI)

    Lye, Ming F.; Fanning, Alan S.; Su, Ying; Anderson, James M.; Lavie, Arnon (UNC); (UIC)

    2010-11-09

    Tight junctions are dynamic components of epithelial and endothelial cells that regulate the paracellular transport of ions, solutes, and immune cells. The assembly and permeability of these junctions is dependent on the zonula occludens (ZO) proteins, members of the membrane-associated guanylate kinase homolog (MAGUK) protein family, which are characterized by a core Src homology 3 (SH3)-GUK module that coordinates multiple protein-protein interactions. The structure of the ZO-1 SH3-GUK domain confirms that the interdependent folding of the SH3 and GUK domains is a conserved feature of MAGUKs, but differences in the orientation of the GUK domains in three different MAGUKs reveal interdomain flexibility of the core unit. Using pull-down assays, we show that an effector loop, the U6 region in ZO-1, forms a novel intramolecular interaction with the core module. This interaction is divalent cation-dependent and overlaps with the binding site for the regulatory molecule calmodulin on the GUK domain. These findings provide insight into the previously observed ability of the U6 region to regulate TJ assembly in vivo and the structural basis for the complex protein interactions of the MAGUK family.

  19. Order Module--DOE O 425.1D, VERIFICATION OF READINESS TO START...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    In the first section we will discuss the purpose of DOE O 425.1D and the requirements for 1) determining the level of readiness review (RR), 2) determining the startup ...

  20. Order Module--DOE O 451.1B, NATIONAL ENVIRONMENTAL POLICY ACT...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    DOE O 451.1B, National Environmental Policy Act Compliance Program, replaces DOE O 451.1A of the same name. DOE O 451.1B is ten pages long. Due to the concise nature of this Order, ...

  1. Wwox suppresses breast cancer cell growth through modulation of the hedgehog–GLI1 signaling pathway

    SciTech Connect (OSTI)

    Xiong, Anwen; Wei, Li; Ying, Mingzhen; Wu, Hongmei; Hua, Jin; Wang, Yajie

    2014-01-24

    Highlights: • We investigated Gli1 as a novel partner of Wwox. • We observed a physical association between Wwox and the Gli1. • Wwox–Gli1 interaction affects Gli1 intracellular localization. • Gli1 Blocks Wwox-induced growth inhibition and apoptosis in T47D cells. - Abstract: Wwox is a tumor suppressor that is frequently deleted or altered in several cancer types, including breast cancer. Previous studies have shown that ectopic expression of Wwox inhibits proliferation of breast cancer cells. However, the underlying mechanism remains unclear. To better understand the molecular mechanisms of Wwox function, we investigated novel partners of this protein. Utilizing the coimmunoprecipitation assay, we observed a physical association between Wwox and the Gli1 zinc-finger transcription factor involved in the hedgehog pathway. Our results further demonstrated that Wwox expression triggered redistribution of nuclear Gli1 to the cytoplasm. Additionally, ectopic expression of Wwox reduced Gli1 expression in vitro. Furthermore, Gli1 Blocks Wwox-induced breast cancer cell growth inhibition. These findings suggest a functional crosstalk between Wwox and hedgehog–GLI1 signaling pathway in tumorigenesis.

  2. Order Module--DOE Order 225.1B, ACCIDENT INVESTIGATIONS

    Broader source: Energy.gov [DOE]

    DOE O 225.1B prescribes organizational responsibilities, authorities, and requirements for conducting investigations of certain accidents occurring at DOE sites, facilities, areas, operations, and...

  3. User Instructions for the Systems Assessment Capability, Rev. 1, Computer Codes Volume 1: Inventory, Release, and Transport Modules

    SciTech Connect (OSTI)

    Eslinger, Paul W.; Miley, Terri B.; Engel, David W.; Nichols, William E.; Gerhardstein, Lawrence H.; Strenge, Dennis L.; Lopresti, Charles A.; Wurstner, Signe K.

    2004-09-12

    This document contains detailed user instructions for the transport codes for Rev. 1 of the System Assessment Capability.

  4. "A Regulator's Privacy Guide to Third-Party Data Access for Energy...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    "A Regulator's Privacy Guide to Third-Party Data Access for Energy Efficiency" Now Available "A Regulator's Privacy Guide to Third-Party Data Access for Energy Efficiency" Now...

  5. Data Privacy and the Smart Grid: A Voluntary Code of Conduct...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Data Privacy and the Smart Grid: A Voluntary Code of Conduct (VCC) - Draft for Public Comment (September 2014) Data Privacy and the Smart Grid: A Voluntary Code of Conduct (VCC) - ...

  6. CPEB1 modulates lipopolysaccharide-mediated iNOS induction in rat primary astrocytes

    SciTech Connect (OSTI)

    Kim, Ki Chan; Hyun Joo, So; Shin, Chan Young

    2011-06-17

    Highlights: {yields} Expression and phosphorylation of CPEB1 is increased by LPS stimulation in rat primary astrocytes. {yields} JNK regulates expression and phosphorylation of CPEB1 in reactive astrocytes. {yields} Down-regulation of CPEB1 using siRNA inhibits oxidative stress and iNOS induction by LPS stimulation. {yields} CPEB1 may play an important role in regulating inflammatory responses in reactive astrocytes induced by LPS. -- Abstract: Upon CNS damage, astrocytes undergo a series of biological changes including increased proliferation, production of inflammatory mediators and morphological changes, in a response collectively called reactive gliosis. This process is an essential part of the brains response to injury, yet much is unknown about the molecular mechanism(s) that induce these changes. In this study, we investigated the role of cytoplasmic polyadenylation element binding protein 1 (CPEB1) in the regulation of inflammatory responses in a model of reactive gliosis, lipopolysaccharide-stimulated astrocytes. CPEB1 is an mRNA-binding protein recently shown to be expressed in astrocytes that may play a role in astrocytes migration. After LPS stimulation, the expression and phosphorylation of CPEB1 was increased in rat primary astrocytes in a JNK-dependent process. siRNA-induced knockdown of CPEB1 expression inhibited the LPS-induced up-regulation of iNOS as well as NO and ROS production, a hallmark of immunological activation of astrocytes. The results from the study suggest that CPEB1 is actively involved in the regulation of inflammatory responses in astrocytes, which might provide new insights into the regulatory mechanism after brain injury.

  7. Aluminium induced oxidative stress results in decreased mitochondrial biogenesis via modulation of PGC-1? expression

    SciTech Connect (OSTI)

    Sharma, Deep Raj; Sunkaria, Aditya; Wani, Willayat Yousuf; Sharma, Reeta Kumari; Kandimalla, Ramesh J.L.; Bal, Amanjit; Gill, Kiran Dip

    2013-12-01

    The present investigation was carried out to elucidate a possible molecular mechanism related to the effects of aluminium-induced oxidative stress on various mitochondrial respiratory complex subunits with special emphasis on the role of Peroxisome proliferator activated receptor gamma co-activator 1? (PGC-1?) and its downstream targets i.e. Nuclear respiratory factor-1(NRF-1), Nuclear respiratory factor-2(NRF-2) and Mitochondrial transcription factor A (Tfam) in mitochondrial biogenesis. Aluminium lactate (10 mg/kg b.wt./day) was administered intragastrically to rats for 12 weeks. After 12 weeks of exposure, we found an increase in ROS levels, mitochondrial DNA oxidation and decrease in citrate synthase activity in the Hippocampus (HC) and Corpus striatum (CS) regions of rat brain. On the other hand, there was a decrease in the mRNA levels of the mitochondrial encoded subunitsNADH dehydrogenase (ND) subunits i.e. ND1, ND2, ND3, Cytochrome b (Cytb), Cytochrome oxidase (COX) subunits i.e. COX1, COX3, ATP synthase (ATPase) subunit 6 along with reduced expression of nuclear encoded subunits COX4, COX5A, COX5B of Electron transport chain (ETC). Besides, a decrease in mitochondrial DNA copy number and mitochondrial content in both regions of rat brain was observed. The PGC-1? was down-regulated in aluminium treated rats along with NRF-1, NRF-2 and Tfam, which act downstream from PGC-1? in aluminium treated rats. Electron microscopy results revealed a significant increase in the mitochondrial swelling, loss of cristae, chromatin condensation and decreases in mitochondrial number in case of aluminium treated rats as compared to control. So, PGC-1? seems to be a potent target for aluminium neurotoxicity, which makes it an almost ideal target to control or limit the damage that has been associated with the defective mitochondrial function seen in neurodegenerative diseases. - Highlights: Aluminium decreases the mRNA levels of mitochondrial and nuclear encoded subunits

  8. Public Roundtable- Data Access and Privacy Issues Related to Smart Grid

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Technologies | Department of Energy Roundtable- Data Access and Privacy Issues Related to Smart Grid Technologies Public Roundtable- Data Access and Privacy Issues Related to Smart Grid Technologies Transcript of public meeting regarding Data Access and Privacy Issues Related to Smart Grid Technologies Public Roundtable- Data Access and Privacy Issues Related to Smart Grid Technologies (292.33 KB) More Documents & Publications Testimony Public Meeting Transcript: Sustainable Design

  9. LM Records Handling System-Freedom of Information/Privacy Act, Office of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Legacy management | Department of Energy Freedom of Information/Privacy Act, Office of Legacy management LM Records Handling System-Freedom of Information/Privacy Act, Office of Legacy management LM Records Handling System-Freedom of Information/Privacy Act, Office of Legacy management LM Records Handling System-Freedom of Information/Privacy Act, Office of Legacy management (503.75 KB) More Documents & Publications LM Records Handling System-Fernald Historical Records System, Office of

  10. Data Privacy and the Smart Grid: A Voluntary Code of Conduct (VCC) - Draft

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    for Public Comment (September 2014) | Department of Energy Data Privacy and the Smart Grid: A Voluntary Code of Conduct (VCC) - Draft for Public Comment (September 2014) Data Privacy and the Smart Grid: A Voluntary Code of Conduct (VCC) - Draft for Public Comment (September 2014) In January 2012, OE hosted a Smart Grid Privacy Workshop to facilitate a dialogue among key industry stakeholders. In addition, in February 2012, the White House released the report, Consumer Data Privacy in a

  11. NBP RFI: Data Access, Third Party Use and Privacy- Comments of Baltimore

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Gas & Electric Company | Department of Energy Use and Privacy- Comments of Baltimore Gas & Electric Company NBP RFI: Data Access, Third Party Use and Privacy- Comments of Baltimore Gas & Electric Company Comments from Baltimore Gas & Electric on DOE Request for Information-Implementing the National Broadband Plan by Empowering Customers and the Smart Grid: Data Access, Third Party Use, and Privacy NBP RFI: Data Access, Third Party Use and Privacy- Comments of Baltimore Gas

  12. DOE Order Self Study Modules - DOE O 425.1D, Verification of...

    Office of Environmental Management (EM)

    ... restart nuclear facilities in accordance with DOE O 226.1B, Implementation of Department of Energy Oversight Policy, and DOE-STD-3006, Planning and Conducting Readiness Reviews. ...

  13. Order Module--DOE O 420.1B, FACILITY SAFETY | Department of Energy

    Broader source: Energy.gov (indexed) [DOE]

    To ensure that new DOE nuclear reactors comply with the requirements of DOE O 420.1B and the design requirements of DOE O 5480.30, Nuclear Reactor Safety Design Criteria. DOE Order ...

  14. EOS7CA Version 1.0: TOUGH2 Module for Gas Migration in Shallow Subsurface Porous Media Systems

    SciTech Connect (OSTI)

    Oldenburg, Curtis M.

    2015-06-22

    EOS7CA is a TOUGH2 module for mixtures of a non-condensible gas (NCG) and air (with or without a gas tracer), an aqueous phase, and water vapor. The user can select the NCG as being CO2, N2, or CH4. EOS7CA uses a cubic equation of state with a multiphase version of Darcy’s Law to model flow and transport of gas and aqueous phase mixtures over a range of pressures and temperatures appropriate to shallow subsurface porous media systems. The limitation to shallow systems arises from the use of Henry’s Law for gas solubility which is appropriate for low pressures but begins to over-predict solubility starting at pressures greater than approximately 1 MPa (10 bar). The components modeled in EOS7CA are water, brine, NCG, gas tracer, air, and optional heat.

  15. EOS7CA Version 1.0: TOUGH2 Module for Gas Migration in Shallow Subsurface Porous Media Systems

    Energy Science and Technology Software Center (OSTI)

    2015-06-22

    EOS7CA is a TOUGH2 module for mixtures of a non-condensible gas (NCG) and air (with or without a gas tracer), an aqueous phase, and water vapor. The user can select the NCG as being CO2, N2, or CH4. EOS7CA uses a cubic equation of state with a multiphase version of Darcy’s Law to model flow and transport of gas and aqueous phase mixtures over a range of pressures and temperatures appropriate to shallow subsurface porousmore » media systems. The limitation to shallow systems arises from the use of Henry’s Law for gas solubility which is appropriate for low pressures but begins to over-predict solubility starting at pressures greater than approximately 1 MPa (10 bar). The components modeled in EOS7CA are water, brine, NCG, gas tracer, air, and optional heat.« less

  16. Development of Automated Production Line Processes for Solar Brightfield Modules: Final Report, 1 June 2003-30 November 2007

    SciTech Connect (OSTI)

    Nowlan, M.

    2008-04-01

    Summary of progress by Spire Corporation under NREL's PV Manufacturing R&D Project to develop new automated systems for fabricating very large photovoltaic modules.

  17. DOE Order Self Study Modules - DOE O 460.1C Packaging and Transportation Safety and DOE O 460.2A Departmental Materials Transportation and Packaging Management

    Office of Environmental Management (EM)

    2.1 DEPARTMENT OF ENERGY EMPLOYEE CONCERNS PROGRAM ALBUQUERQUE OPERATIONS OFFICE Change No: 0 DOE O 442.1 Level: Familiar Date: 6/15/01 1 DOE O 442.1 DOE EMPLOYEE CONCERNS PROGRAM FAMILIAR LEVEL _________________________________________________________________________ OBJECTIVES Given the familiar level of this module and the resources listed below, you will be able to perform the following: 1. State three examples of criteria that should be used to assess the significance of an employee's

  18. Binding Preferences, Surface Attachment, Diffusivity, and Orientation of a Family 1 Carbohydrate-Binding Module on Cellulose

    SciTech Connect (OSTI)

    Nimlos, M. R.; Beckham, G. T.; Matthews, J. F.; Bu, L.; Himmel, M. E.; Crowley, M. F.

    2012-06-08

    Cellulase enzymes often contain carbohydrate-binding modules (CBMs) for binding to cellulose. The mechanisms by which CBMs recognize specific surfaces of cellulose and aid in deconstruction are essential to understand cellulase action. The Family 1 CBM from the Trichoderma reesei Family 7 cellobiohydrolase, Cel7A, is known to selectively bind to hydrophobic surfaces of native cellulose. It is most commonly suggested that three aromatic residues identify the planar binding face of this CBM, but several recent studies have challenged this hypothesis. Here, we use molecular simulation to study the CBM binding orientation and affinity on hydrophilic and hydrophobic cellulose surfaces. Roughly 43 {mu}s of molecular dynamics simulations were conducted, which enables statistically significant observations. We quantify the fractions of the CBMs that detach from crystal surfaces or diffuse to other surfaces, the diffusivity along the hydrophobic surface, and the overall orientation of the CBM on both hydrophobic and hydrophilic faces. The simulations demonstrate that there is a thermodynamic driving force for the Cel7A CBM to bind preferentially to the hydrophobic surface of cellulose relative to hydrophilic surfaces. In addition, the simulations demonstrate that the CBM can diffuse from hydrophilic surfaces to the hydrophobic surface, whereas the reverse transition is not observed. Lastly, our simulations suggest that the flat faces of Family 1 CBMs are the preferred binding surfaces. These results enhance our understanding of how Family 1 CBMs interact with and recognize specific cellulose surfaces and provide insights into the initial events of cellulase adsorption and diffusion on cellulose.

  19. Facility effluent monitoring plan for the Waste Receiving and Processing Facility Module 1

    SciTech Connect (OSTI)

    Lewis, C.J.

    1995-10-01

    A facility effluent monitoring plan is required by the US Department of Energy in Order 5400.1 for any operations that involve hazardous materials and radioactive substances that could impact employee or public safety or the environment. This document is prepared using the specific guidelines identified in A Guide for Preparing Hanford Site Facility Effluent Monitoring Plans, WHC-EP-0438. This facility effluent monitoring plan assesses effluent monitoring systems and evaluates whether they are adequate to ensure the public health and safety as specified in applicable federal state, and local requirements. This facility effluent monitoring plan shall ensure lonq-range integrity of the effluent monitoring systems by requiring an update whenever a new process or operation introduces new hazardous materials or significant radioactive materials. This document must be reviewed annually even if there are no operational changes, and it must be updated as a minimum every three years.

  20. Freedom of Information Act (FOIA) and Privacy Act Requests | Department of

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Energy Freedom of Information Act (FOIA) and Privacy Act Requests Freedom of Information Act (FOIA) and Privacy Act Requests FOIA and Privacy Act Requests FOIA Requests FOIA Requester Service Center 1000 Independence Avenue, SW Mail Stop MA-90 Washington, DC 20585 Or by facsimile at (202) 586-0575. If you have any questions, please give us a call at (202) 586-5955. Privacy Act Requests Privacy Act requests can not be submitted electronically. They must be submitted in writing or in person

  1. Weatherization Guidance on Maintaining Privacy of Recipients of Services

    Broader source: Energy.gov [DOE]

    U.S. Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy (EERE) Weatherization Assistance Program Notice 10-08 dealing with requirements of weatherization service providers to maintain the privacy of low-income residents receiving energy efficiency services in their homes.

  2. Module Configuration

    DOE Patents [OSTI]

    Oweis, Salah; D'Ussel, Louis; Chagnon, Guy; Zuhowski, Michael; Sack, Tim; Laucournet, Gaullume; Jackson, Edward J.

    2002-06-04

    A stand alone battery module including: (a) a mechanical configuration; (b) a thermal management configuration; (c) an electrical connection configuration; and (d) an electronics configuration. Such a module is fully interchangeable in a battery pack assembly, mechanically, from the thermal management point of view, and electrically. With the same hardware, the module can accommodate different cell sizes and, therefore, can easily have different capacities. The module structure is designed to accommodate the electronics monitoring, protection, and printed wiring assembly boards (PWAs), as well as to allow airflow through the module. A plurality of modules may easily be connected together to form a battery pack. The parts of the module are designed to facilitate their manufacture and assembly.

  3. Research on stable, high-efficiency amorphous silicon multijunction modules. Final subcontract report, 1 January 1991--31 August 1994

    SciTech Connect (OSTI)

    Guha, S.

    1994-10-01

    The principal objective of this program is to conduct research on semiconductor materials and non-semiconductor materials to enhance the performance of multibandgap, multijunction, large-area amorphous silicon-based alloy modules. The goal for this program is to demonstrate stabilized module efficiency of 12% for multijunction modules of area greater than 900 cm{sup 2}. Double-junction and triple-junction cells are made on Ag/ZnO back reflector deposited on stainless steel substrates. The top cell uses a-Si alloy; a-SiGe alloy is used for the i layer in the middle and the bottom cells. After evaporation of antireflection coating, silver grids and bus bars are put on the top surface, and the panel is encapsulated in an ethylene vinyl acetate (EVA)/Tefzel structure to make a one-square-foot monolithic module.

  4. Structure and Function of the Clostridium thermocellum Cellobiohydrolase A X1-Module Repeat: Enhancement Through Stabilization of the CbhA Complex

    SciTech Connect (OSTI)

    Brunecky, R.; Alahuhta, M.; Bomble, Y. J.; Xu, Q.; Baker, J. O.; Ding, S. Y.; Himmel, M. E.; Lunin, V. V.

    2012-03-01

    The efficient deconstruction of lignocellulosic biomass remains a significant barrier to the commercialization of biofuels. Whereas most commercial plant cell-wall-degrading enzyme preparations used today are derived from fungi, the cellulosomal enzyme system from Clostridium thermocellum is an equally effective catalyst, yet of considerably different structure. A key difference between fungal enzyme systems and cellulosomal enzyme systems is that cellulosomal enzyme systems utilize self-assembled scaffolded multimodule enzymes to deconstruct biomass. Here, the possible function of the X1 modules in the complex multimodular enzyme system cellobiohydrolase A (CbhA) from C. thermocellum is explored. The crystal structures of the two X1 modules from C. thermocellum CbhA have been solved individually and together as one construct. The role that calcium may play in the stability of the X1 modules has also been investigated, as well as the possibility that they interact with each other. Furthermore, the results show that whereas the X1 modules do not seem to act as cellulose disruptors, they do aid in the thermostability of the CbhA complex, effectively allowing it to deconstruct cellulose at a higher temperature.

  5. MiR-145 is downregulated in human ovarian cancer and modulates cell growth and invasion by targeting p70S6K1 and MUC1

    SciTech Connect (OSTI)

    Wu, Huijuan; Xiao, ZhengHua; Wang, Ke; Liu, Wenxin; Hao, Quan

    2013-11-29

    Highlights: MiR-145 is downregulated in human ovarian cancer. MiR-145 targets p70S6K1 and MUC1. p70S6K1 and MUC1 are involved in miR-145 mediated tumor cell growth and cell invasion, respectively. -- Abstract: MicroRNAs (miRNAs) are a family of small non-coding RNA molecules that regulate gene expression at post-transcriptional levels. Previous studies have shown that miR-145 is downregulated in human ovarian cancer; however, the roles of miR-145 in ovarian cancer growth and invasion have not been fully demonstrated. In the present study, Northern blot and qRT-PCR analysis indicate that miR-145 is downregulated in ovarian cancer tissues and cell lines, as well as in serum samples of ovarian cancer, compared to healthy ovarian tissues, cell lines and serum samples. Functional studies suggest that miR-145 overexpression leads to the inhibition of colony formation, cell proliferation, cell growth viability and invasion, and the induction of cell apoptosis. In accordance with the effect of miR-145 on cell growth, miR-145 suppresses tumor growth in vivo. MiR-145 is found to negatively regulate P70S6K1 and MUC1 protein levels by directly targeting their 3?UTRs. Importantly, the overexpression of p70S6K1 and MUC1 can restore the cell colony formation and invasion abilities that are reduced by miR-145, respectively. MiR-145 expression is increased after 5-aza-CdR treatment, and 5-aza-CdR treatment results in the same phenotype as the effect of miR-145 overexpression. Our study suggests that miR-145 modulates ovarian cancer growth and invasion by suppressing p70S6K1 and MUC1, functioning as a tumor suppressor. Moreover, our data imply that miR-145 has potential as a miRNA-based therapeutic target for ovarian cancer.

  6. Protecting Privacy of Shared Epidemiologic Data without Compromising Analysis Potential

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Cologne, John; Grant, Eric J.; Nakashima, Eiji; Chen, Yun; Funamoto, Sachiyo; Katayama, Hiroaki

    2012-01-01

    Objective . Ensuring privacy of research subjects when epidemiologic data are shared with outside collaborators involves masking (modifying) the data, but overmasking can compromise utility (analysis potential). Methods of statistical disclosure control for protecting privacy may be impractical for individual researchers involved in small-scale collaborations. Methods . We investigated a simple approach based on measures of disclosure risk and analytical utility that are straightforward for epidemiologic researchers to derive. The method is illustrated using data from the Japanese Atomic-bomb Survivor population. Results . Masking by modest rounding did not adequately enhance security but rounding to remove several digits ofmore » relative accuracy effectively reduced the risk of identification without substantially reducing utility. Grouping or adding random noise led to noticeable bias. Conclusions . When sharing epidemiologic data, it is recommended that masking be performed using rounding. Specific treatment should be determined separately in individual situations after consideration of the disclosure risks and analysis needs.« less

  7. Information integrity and privacy for computerized medical patient records

    SciTech Connect (OSTI)

    Gallegos, J.; Hamilton, V.; Gaylor, T.; McCurley, K.; Meeks, T.

    1996-09-01

    Sandia National Laboratories and Oceania, Inc. entered into a Cooperative Research and Development Agreement (CRADA) in November 1993 to provide ``Information Integrity and Privacy for Computerized Medical Patient Records`` (CRADA No. SC93/01183). The main objective of the project was to develop information protection methods that are appropriate for databases of patient records in health information systems. This document describes the findings and alternative solutions that resulted from this CRADA.

  8. NBP RFI: Data Access, Third Party Use and Privacy- Comments of Utilities

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Telecom Council | Department of Energy Use and Privacy- Comments of Utilities Telecom Council NBP RFI: Data Access, Third Party Use and Privacy- Comments of Utilities Telecom Council The Utilities Telecom Council hereby comments in response to the Department of Energy (DOE) request for information on data access, third party use, and privacy. In summary, UTC submits that the innovative deployment by energy utilities of smart meters and smart control systems will create a smart energy grid

  9. Thermal Modeling of NUHOMS HSM-15 and HSM-1 Storage Modules at Calvert Cliffs Nuclear Power Station ISFSI

    SciTech Connect (OSTI)

    Suffield, Sarah R.; Fort, James A.; Adkins, Harold E.; Cuta, Judith M.; Collins, Brian A.; Siciliano, Edward R.

    2012-10-01

    As part of the Used Fuel Disposition Campaign of the Department of Energy (DOE), visual inspections and temperature measurements were performed on two storage modules in the Calvert Cliffs Nuclear Power Station’s Independent Spent Fuel Storage Installation (ISFSI). Detailed thermal models models were developed to obtain realistic temperature predictions for actual storage systems, in contrast to conservative and bounding design basis calculations.

  10. SCALE: A modular code system for performing standardized computer analyses for licensing evaluation: Functional modules F1-F8

    SciTech Connect (OSTI)

    1997-03-01

    This Manual represents Revision 5 of the user documentation for the modular code system referred to as SCALE. The history of the SCALE code system dates back to 1969 when the current Computational Physics and Engineering Division at Oak Ridge National Laboratory (ORNL) began providing the transportation package certification staff at the U.S. Atomic Energy Commission with computational support in the use of the new KENO code for performing criticality safety assessments with the statistical Monte Carlo method. From 1969 to 1976 the certification staff relied on the ORNL staff to assist them in the correct use of codes and data for criticality, shielding, and heat transfer analyses of transportation packages. However, the certification staff learned that, with only occasional use of the codes, it was difficult to become proficient in performing the calculations often needed for an independent safety review. Thus, shortly after the move of the certification staff to the U.S. Nuclear Regulatory Commission (NRC), the NRC staff proposed the development of an easy-to-use analysis system that provided the technical capabilities of the individual modules with which they were familiar. With this proposal, the concept of the Standardized Computer Analyses for Licensing Evaluation (SCALE) code system was born. This volume consists of the section of the manual dealing with eight of the functional modules in the code. Those are: BONAMI - resonance self-shielding by the Bondarenko method; NITAWL-II - SCALE system module for performing resonance shielding and working library production; XSDRNPM - a one-dimensional discrete-ordinates code for transport analysis; XSDOSE - a module for calculating fluxes and dose rates at points outside a shield; KENO IV/S - an improved monte carlo criticality program; COUPLE; ORIGEN-S - SCALE system module to calculate fuel depletion, actinide transmutation, fission product buildup and decay, and associated radiation source terms; ICE.

  11. Privacy Act Advisory | U.S. DOE Office of Science (SC)

    Office of Science (SC) Website

    Freedom of Information ActPrivacy Act Officer U.S. Department of Energy SC Integrated ... to FOIA requests; to maintain case files to comply with records disposal ...

  12. A Regulator's Privacy Guide to Third-Party Data Access for Energy...

    Broader source: Energy.gov (indexed) [DOE]

    approaches taken by states on privacy and security issues related to third-party access to customer data and provides guidance on policy options for providing access to...

  13. Module Experimental Process System Development Unit (MEPSDU). Quarterly report No. 1, November 26, 1980-February 28, 1981

    SciTech Connect (OSTI)

    Not Available

    1981-01-01

    The purpose of this program is to demonstrate the technical readiness of a cost-effective process sequence that has the potential for the production of flat plate photovoltaic modules which met the price goal in 1986 of 70 cents or less per Watt peak. During this initial program quarter, the efforts have included preparation and submission of the Work Breakdown Structure, the Baseline Cost Estimate and the Program Plan. The proposed process sequence was reviewed and laboratory verification experiments were conducted. The preliminary process includes the following features: semicrystalline silicon (10 cm x 10 cm) as the silicon input material, spray-on dopant diffusion source, Al paste BSF formation, spray-on AR coating, electroless Ni plate-solder dip Metallization, laser scribe edges, K and S tabbing and stringing machine, and laminated EVA modules.

  14. Research on stable, high-efficiency amorphous silicon multijunction modules. Annual subcontract report, 1 December 1991--31 October 1992

    SciTech Connect (OSTI)

    Ghosh, M.; DelCueto, J.: Kampas, F.; Xi, J.

    1993-02-01

    This report describes results from the first phase of a three-phase contract for the development of stable, high-efficiency, same-band-gap, amorphous silicon (a-Si) multijunction photovoltaic (PV) modules. The program involved improving the properties of individual layers of semiconductor and non-semiconductor materials and small-area single-junction and multijunction devices, as well as the multijunction modules. The semiconductor materials research was performed on a-Si p, i, and n layers, and on microcrystalline silicon n layers. These were deposited using plasma-enhanced chemical vapor deposition. The non-semiconductor materials studied were tin oxide, for use as a transparent-conducting-oxide (TCO), and zinc oxide, for use as a back reflector and as a buffer layer between the TCO and the semiconductor layers. Tin oxide was deposited using atmospheric-pressure chemical vapor deposition. Zinc oxide was deposited using magnetron sputtering. The research indicated that the major challenge in the fabrication of a-Si multijunction PV modules is the contact between the two p-i-n cells. A structure that has low optical absorption but that also facilitates the recombination of electrons from the first p-i-n structure with holes from the second p-i-n structure is required. Non-semiconductor layers and a-Si semiconductor layers were tested without achieving the desired result.

  15. BPA-2011-00311-Privacy Act Request

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    B1' YOU OFFICE THIS DATE: 11,f11 DUE DATE: LOG 0 -)i -- Dd--A4 Page 1 of 2 Winn,Kim S - DK-7 From: Sent: Sunday, April 17, 2011 11:22 PM To: FOIA Subject: FOIA Request The...

  16. Initial test results from the RedFlow 5 kW, 10 kWh zinc-bromide module, phase 1.

    SciTech Connect (OSTI)

    Ferreira, Summer Rhodes; Rose, David Martin

    2012-02-01

    In this paper the performance results of the RedFlow zinc-bromide module (ZBM) Gen 2.0 are reported for Phase 1 of testing, which includes initial characterization of the module. This included physical measurement, efficiency as a function of charge and discharge rates, efficiency as a function of maximum charge capacity, duration of maximum power supplied, and limited cycling with skipped strip cycles. The goal of this first phase of testing was to verify manufacturer specifications of the zinc-bromide flow battery. Initial characterization tests have shown that the ZBM meets the manufacturer's specifications. Further testing, including testing as a function of temperature and life cycle testing, will be carried out during Phase 2 of the testing, and these results will be issued in the final report, after Phase 2 testing has concluded.

  17. A Regulator's Privacy Guide to Third-Party Data Access for Energy Efficiency

    Office of Energy Efficiency and Renewable Energy (EERE)

    A Regulator's Privacy Guide to Third-Party Data Access for Energy Efficiency summarizes approaches taken by states on privacy and security issues related to third-party access to customer data and provides guidance on policy options for providing access to customer data.

  18. Solar-parabolic dish-Stirling-engine-system module. Task 1: Topical report, market assessment/conceptual design

    SciTech Connect (OSTI)

    Not Available

    1982-11-30

    The major activities reported are: a market study to identify an early market for a dish-Stirling module and assess its commercial potential; preparation of a conceptual system and subsystem design to address this market; and preparation of an early sales implementation plan. A study of the reliability of protection from the effects of walk-off, wherein the sun's image leaves the receiver if the dish is not tracking, is appended, along with an optical analysis and structural analysis. Also appended are the relationship between PURPA and solar thermal energy development and electric utility pricing rationale. (LEW)

  19. Privacy Act Requests | National Nuclear Security Administration | (NNSA)

    National Nuclear Security Administration (NNSA)

    Requests How to make a request Requests for records pursuant to the Act can be submitted to the NNSA Albuquerque Complex in writing at the following address: NNSA Albuquerque Complex Office of the General Counsel P. O. Box 5400 Albuquerque, NM 87185-5400 In your request, please advise you are requesting the records pursuant to the Privacy Act of 1974 and describe the records being sought as clearly as possible and state whether you are seeking access or requesting an amendment. You may request

  20. Commercial and Multifamily Building Tenant Energy Usage Aggregation and Privacy

    SciTech Connect (OSTI)

    Livingston, Olga V.; Pulsipher, Trenton C.; Wang, Na

    2014-11-17

    In a number of cities and states, building owners are required to disclose and/or benchmark their building energy use. This requires the building owner to possess monthly whole-building energy usage information, which can be challenging for buildings in which individual tenants have their own utility meters and accounts with the utility. Some utilities and utility regulators have turned to aggregation of customer data as a way to give building owners the whole-building energy usage data while protecting customer privacy. However, no utilities or regulators appear to have conducted a concerted statistical, cybersecurity, and privacy analysis to justify the level of aggregation selected. Therefore, the Tennant Data Aggregation Task was established to help utilities address these issues and provide recommendations as well as a theoretical justification of the aggregation threshold. This study is focused on the use case of submitting data for ENERGY STAR Portfolio Manager (ESPM), but it also looks at other potential use cases for monthly energy consumption data.

  1. Single crystal neutron diffraction study of lattice and magnetic structures of 5M modulated Ni2Mn1.14Ga0.86

    SciTech Connect (OSTI)

    Pramanick, Abhijit; Wang, Xiaoping; An, Ke; Stoica, Alexandru Dan; Hoffmann, Christina; Wang, Xun-Li

    2012-01-01

    A comprehensive description of the crystal and magnetic structures of Ni-Mn-Ga magnetic shape memory alloys is important to understand the physical origins of their magnetoelastic properties. These structural details for an off-stoichiometric Ni2Mn1.14Ga0.86 alloy have been obtained from refinement of high-resolution single crystal neutron diffraction data following a (3+1)-dimensional superspace formalism. In particular, the structure adopts a P2/m( 0 )00 (3+1)-D superspace symmetry with the following fundamental lattice parameters: a=4.255(4) , b=5.613(4) , c=4.216(3) , a commensurate periodicity of 5M and a modulation wave vector of . The magnetic moments are aligned along the b-axis. The modulations for atomic site displacements, site occupancies and magnetic moments are elucidated from a (3+1)-D refinement of the neutron diffraction data. In addition to atomic displacements corresponding to shear waves along <110>, distortions of Ni-centric tetrahedra are also evident. Physical interpretations for the different structural distortions and their relationship with magnetic properties are discussed.

  2. EOS7C Version 1.0 TOUGH2 Module for Carbon Dioxide or Nitrogen in Natural Gas

    Energy Science and Technology Software Center (OSTI)

    2008-01-11

    EOS7C is a TOUGH2 module for multicomponent gas mixtures in the systems methane-carbon dioxide (CH{sub 4}-CO{sub 2}) or methane-nitrogen (CH{sub 4}-N{sub 2}) with or without an aqueous phase and H{sub 2}O vapor. EOS7C uses a cubic equation of state and an accurate solubility formulation along with a multiphase Darcy's Law to model flow and transport of gas and aqueous phase mixtures over a wide range of pressures and temperatures appropriate to subsurface geologic carbon sequestrationmore » sites and natural gas reservoirs. EOS7C models supercritical CO{sub 2{ and subcritical CO{sub 2} as a non-condensible gas, hence EOS7C does not model the transitions to liquid or solid CO{sub 2} conditions. The components modeled in EOS7C are water, brine, non-condensible gas, gas tracer, methane, and optional heat. The non-condensible gas (NCG) can be selected by the user to be CO{sub 2} or N{sub 2}. The real gas properties module has options for Peng-Robinson, Redlich-Kwong, or Soave-Redlich-Kwong equations of state to calculate gas mixture density, enthalpy departure, and viscosity. Partitioning of the NCG and CH{sub 4} between the aqueous and gas phases is calculated using a very accurate chemical equilibrium approach. Transport of the gaseous and dissolved components is by advection and Fickian molecular diffusion. EOS7C is written in FORTAN77.« less

  3. DOE F 1800.1

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    800.1 (11-96) All Other Editions Are Obsolete U.S. DEPARTMENT OF ENERGY PRIVACY ACT INFORMATION REQUEST (NOTE: Use of this form is recommended, but is not mandatory) OMB Control...

  4. Neutron-scattering evidence for a periodically modulated superconducting phase in the underdoped cuprate La1.905Ba0.095CuO4

    DOE Public Access Gateway for Energy & Science Beta (PAGES Beta)

    Xu, Zhijun; Stock, C.; Chi, Songxue; Kolesnikov, A. I.; Xu, Guangyong I.; Gu, Genda; Tranquada, J. M.

    2014-10-01

    The role of antiferromagnetic spin correlations in high-temperature superconductors remains a matter of debate. We present inelastic neutron-scattering evidence that gapless spin fluctuations coexist with superconductivity in La1.905Ba0.095CuO4. Furthermore, we observe that both the low-energy magnetic spectral weight and the spin incommensurability are enhanced with the onset of superconducting correlations. We propose that the coexistence occurs through intertwining of spatial modulations of the pair wave function and the antiferromagnetic correlations. This proposal is also directly relevant to sufficiently underdoped La2-xSrxCuO4 and YBa2Cu3O6+x.

  5. Development of large-area monolithically integrated silicon-film{trademark} photovoltaic modules. Final subcontract report, May 1, 1991--December 31, 1994

    SciTech Connect (OSTI)

    Hall, R.B.; Rand, J.A.; Cotter, J.E.

    1995-04-01

    The objective of this program is to develop Silicon Film{trademark} Product III into a low-cost, stable solar cell for large-scale terrestrial power applications. The Product III structure is a thin (<100 {mu}m) polycrystalline layer of silicon on a durable, insulating, ceramic substrate. The insulating substrate allows the silicon layer to be isolated and metallized to form a monolithically interconnected array of solar cells. High efficiency is achieved by the use of light trapping and passivated surfaces. This project focused on the development of five key technologies associated with the monolithic sub-module device structure: (1) development of the film deposition and growth processes; (2) development of the low-cost ceramic substrate; (3) development of a metallurgical barrier technology; (4) development of sub-element solar cell processing techniques; and (5) development of sub-module (isolation and interconnection) processes. This report covers the development approaches and results relating to these technologies. Significant progress has been made in the development of all of the related technologies. This is evidenced by the fabrication of a working 12.0 cm{sup 2} prototype sub-module consisting of 7 elements and testing with an open circuit voltage of 3.9 volts, a short circuit current of 35.2 mA and a fill factor of 63% and an overall efficiency of 7.3%. Another significant result achieved is a 13.4% (NREL verified), 1.0 cm{sup 2} solar cell fabricated from material deposited and grown on a graphite cloth substrate. The significant technological hurdle of the program was and remains the low quality of the photovoltaic layer which is caused by contamination of the photovoltaic layer from the low-cost ceramic substrate by trace impurities found in the substrate precursor materials. The ceramic substrate and metallurgical barrier are being developed specifically to solve this problem.

  6. Thermoelectric module

    DOE Patents [OSTI]

    Kortier, William E.; Mueller, John J.; Eggers, Philip E.

    1980-07-08

    A thermoelectric module containing lead telluride as the thermoelectric mrial is encapsulated as tightly as possible in a stainless steel canister to provide minimum void volume in the canister. The lead telluride thermoelectric elements are pressure-contacted to a tungsten hot strap and metallurgically bonded at the cold junction to iron shoes with a barrier layer of tin telluride between the iron shoe and the p-type lead telluride element.

  7. DOE Convenes Multi-stakeholder Process to Address Privacy for Data Enabled

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    by Smart Grid Technologies | Department of Energy Convenes Multi-stakeholder Process to Address Privacy for Data Enabled by Smart Grid Technologies DOE Convenes Multi-stakeholder Process to Address Privacy for Data Enabled by Smart Grid Technologies February 12, 2013 - 3:53pm Addthis DOE's Office of Electricy Delivery and Energy Reliability (OE) issued a notice of an open meeting on Tuesday, February 26, 2013 (9:30 a.m. to 4:30 p.m. ET) of the smart grid data privacy multi-stakeholder

  8. "Data Privacy and the Smart Grid: A Voluntary Code of Conduct" Now

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Available | Department of Energy "Data Privacy and the Smart Grid: A Voluntary Code of Conduct" Now Available "Data Privacy and the Smart Grid: A Voluntary Code of Conduct" Now Available January 12, 2015 - 11:00am Addthis The Office of Electricity Delivery and Energy Reliability (OE) and the Federal Smart Grid Task Force have facilitated a multi-stakeholder process to develop a Voluntary Code of Conduct (VCC) for utilities and third parties that addresses privacy related

  9. Photovoltaic module and module arrays

    DOE Patents [OSTI]

    Botkin, Jonathan; Graves, Simon; Lenox, Carl J. S.; Culligan, Matthew; Danning, Matt

    2012-07-17

    A photovoltaic (PV) module including a PV device and a frame. The PV device has a PV laminate defining a perimeter and a major plane. The frame is assembled to and encases the laminate perimeter, and includes leading, trailing, and side frame members, and an arm that forms a support face opposite the laminate. The support face is adapted for placement against a horizontal installation surface, to support and orient the laminate in a non-parallel or tilted arrangement. Upon final assembly, the laminate and the frame combine to define a unitary structure. The frame can orient the laminate at an angle in the range of 3.degree.-7.degree. from horizontal, and can be entirely formed of a polymeric material. Optionally, the arm incorporates integral feature(s) that facilitate interconnection with corresponding features of a second, identically formed PV module.

  10. Photovoltaic module and module arrays

    DOE Patents [OSTI]

    Botkin, Jonathan; Graves, Simon; Lenox, Carl J. S.; Culligan, Matthew; Danning, Matt

    2013-08-27

    A photovoltaic (PV) module including a PV device and a frame, The PV device has a PV laminate defining a perimeter and a major plane. The frame is assembled to and encases the laminate perimeter, and includes leading, trailing, and side frame members, and an arm that forms a support face opposite the laminate. The support face is adapted for placement against a horizontal installation surface, to support and orient the laminate in a non-parallel or tilted arrangement. Upon final assembly, the laminate and the frame combine to define a unitary structure. The frame can orient the laminate at an angle in the range of 3.degree.-7.degree. from horizontal, and can be entirely formed of a polymeric material. Optionally, the arm incorporates integral feature(s) that facilitate interconnection with corresponding features of a second, identically formed PV module.

  11. Commercial Building Tenant Energy Usage Aggregation and Privacy

    SciTech Connect (OSTI)

    Livingston, Olga V.; Pulsipher, Trenton C.; Anderson, David M.; Wang, Na

    2014-10-31

    A growing number of building owners are benchmarking their building energy use. This requires the building owner to acquire monthly whole-building energy usage information, which can be challenging for buildings in which individual tenants have their own utility meters and accounts with the utility. Some utilities and utility regulators have turned to aggregation of customer energy use data (CEUD) as a way to give building owners whole-building energy usage data while protecting customer privacy. Meter profile aggregation adds a layer of protection that decreases the risk of revealing CEUD as the number of meters aggregated increases. The report statistically characterizes the similarity between individual energy usage patterns and whole-building totals at various levels of meter aggregation.

  12. Microsoft PowerPoint - FinalModule7.ppt

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    7: Integrated Baseline Review and Change Control Prepared by: Module 7 - Integrated Baseline Review and Change Control 1 Prepared by: Booz Allen Hamilton Module 7: Integrated ...

  13. SENP1 inhibition induces apoptosis and growth arrest of multiple myeloma cells through modulation of NF-κB signaling

    SciTech Connect (OSTI)

    Xu, Jun; Sun, Hui-Yan; Xiao, Feng-Jun; Wang, Hua; Yang, Yang; Wang, Lu; Gao, Chun-Ji; Guo, Zi-Kuan; Wu, Chu-Tse; Wang, Li-Sheng

    2015-05-01

    SUMO/sentrin specific protease 1 (Senp1) is an important regulation protease in the protein sumoylation, which affects the cell cycle, proliferation and differentiation. The role of Senp1 mediated protein desumoylation in pathophysiological progression of multiple myeloma is unknown. In this study, we demonstrated that Senp1 is overexpressed and induced by IL-6 in multiple myeloma cells. Lentivirus-mediated Senp1 knockdown triggers apoptosis and reduces viability, proliferation and colony forming ability of MM cells. The NF-κB family members including P65 and inhibitor protein IkBα play important roles in regulation of MM cell survival and proliferation. We further demonstrated that Senp1 inhibition decreased IL-6-induced P65 and IkBα phosphorylation, leading to inactivation of NF-kB signaling in MM cells. These results delineate a key role for Senp1in IL-6 induced proliferation and survival of MM cells, suggesting it may be a potential new therapeutic target in MM. - Highlights: • Senp1 is overexpressed and induced by IL-6 in multiple myeloma cells. • Senp1 knockdown triggers apoptosis and reduces proliferation of MM cells. • Senp1 inhibition decreased IL-6-induced P65 and IkBα phosphorylation.

  14. A Regulators Privacy Guide to Third-Party Data Access for Energy Efficiency

    SciTech Connect (OSTI)

    Customer Information and Behavior Working Group

    2012-12-20

    Summarizes approaches taken by states on privacy and security issues related to third-party access to customer data and provides guidance on policy options for providing access to customer data.

  15. DOE Hosts Public Roundtable Discussion of Smart-Grid Data Access and Privacy Issues

    Broader source: Energy.gov [DOE]

    On June 29, 2010, the Department of Energy will host a public roundtable panel discussion to collect additional information about the data access and privacy implications of smart-grid technologies...

  16. Genetic secrets: Protecting privacy and confidentiality in the genetic era. Final report

    SciTech Connect (OSTI)

    Rothstein, M.A.

    1998-09-01

    Few developments are likely to affect human beings more profoundly in the long run than the discoveries resulting from advances in modern genetics. Although the developments in genetic technology promise to provide many additional benefits, their application to genetic screening poses ethical, social, and legal questions, many of which are rooted in issues of privacy and confidentiality. The ethical, practical, and legal ramifications of these and related questions are explored in depth. The broad range of topics includes: the privacy and confidentiality of genetic information; the challenges to privacy and confidentiality that may be projected to result from the emerging genetic technologies; the role of informed consent in protecting the confidentiality of genetic information in the clinical setting; the potential uses of genetic information by third parties; the implications of changes in the health care delivery system for privacy and confidentiality; relevant national and international developments in public policies, professional standards, and laws; recommendations; and the identification of research needs.

  17. "A Regulator's Privacy Guide to Third-Party Data Access for Energy Efficiency" Now Available

    Office of Energy Efficiency and Renewable Energy (EERE)

    The State and Local Energy Efficiency Action Network’s (SEE Action) Customer Information and Behavior Working Group has released “A Regulator’s Privacy Guide to Third-Party Data Access for Energy Efficiency.”

  18. EI04~ PRIVACY IMPACT ASSESSMENT: INL PeopleSoft Human Resource

    Broader source: Energy.gov (indexed) [DOE]

    EI04 PRIVACY IMPACT ASSESSMENT: INL PeopleSoft - Human Resource System PIA Template ... Name 'of Infonnatlon System, or IT Project INL PeopleSoft - Human Resource System exhibit ...

  19. Photovoltaic concentrator module improvements study

    SciTech Connect (OSTI)

    Levy, S.L.; Kerschen, K.A. ); Hutchison, G. ); Nowlan, M.J. )

    1991-08-01

    This report presents results of a project to design and fabricate an improved photovoltaic concentrator module. Using previous work as a baseline, this study conducted analyses and testing to select major module components and design features. The lens parquet and concentrator solar cell were selected from the highest performing, available components. A single 185X point-focus module was fabricated by the project team and tested at Sandia. Major module characteristics include a 6 by 4 compression-molded acrylic lens parquet (0.737 m{sup 2} area), twenty-four 0.2 ohms-cm, FZ, p-Si solar cells (1.56 cm{sup 2} area) soldered to ceramic substrates and copper heat spreaders, and an aluminized steel housing with corrugated bottom. This project marked the first attempt to use prismatic covers on solar cells in a high-concentration, point-focus application. Cells with 15 percent metallization were obtained, but problems with the fabrication and placement of prismatic covers on these cells lead to the decision not to use covers in the prototype module. Cell assembly fabrication, module fabrication, and module optical design activities are presented here. Test results are also presented for bare cells, cell assemblies, and module. At operating conditions of 981 watts/m{sup 2} DNI and an estimated cell temperature of 65{degrees}C, the module demonstrated an efficiency of 13.9 percent prior to stressed environmental exposure. 12 refs., 56 figs., 7 tabs.

  20. NBP RFI: Data Access, Third Party Use, and Privacy- Comments of Oncor

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Electric Deliverty Company LLC | Department of Energy Use, and Privacy- Comments of Oncor Electric Deliverty Company LLC NBP RFI: Data Access, Third Party Use, and Privacy- Comments of Oncor Electric Deliverty Company LLC Oncor Electric Delivery Company LLC (Oncor) is a regulated electric transmission and distribution utility that serves the north-central, eastern and western parts of Texas, including the cities of Dallas and Fort Worth. Oncor operates the largest electric transmission and

  1. Modulation of farnesoid X receptor results in post-translational modification of poly (ADP-ribose) polymerase 1 in the liver

    SciTech Connect (OSTI)

    Zhu, Yan; Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, Kansas City, KS ; Li, Guodong; Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, Kansas City, KS ; Dong, Yafeng; Zhou, Helen H.; Kong, Bo; Aleksunes, Lauren M.; Richardson, Jason R.; Li, Fei; Guo, Grace L.

    2013-01-15

    The farnesoid X receptor (FXR) is a bile acid-activated transcription factor belonging to the nuclear receptor superfamily. FXR deficiency in mice results in cholestasis, metabolic disorders, and tumorigenesis in liver and intestine. FXR is known to contribute to pathogenesis by regulating gene transcription; however, changes in the post-transcriptional modification of proteins associated with FXR modulation have not been determined. In the current study, proteomic analysis of the livers of wild-type (WT) and FXR knockout (FXR-KO) mice treated with a FXR synthetic ligand or vehicle was performed. The results identified five proteins as novel FXR targets. Since FXR deficiency in mice leads to liver tumorigenesis, poly (ADP-ribose) polymerase family, member 1 (Parp1) that is important for DNA repair, was validated in the current study by quantitative real-time PCR, and 1- and 2-dimensional gel electrophoresis/western blot. The results showed that Parp1 mRNA levels were not altered by FXR genetic status or by agonist treatment. However, total Parp1 protein levels were increased in FXR-KO mice as early as 3 month old. Interestingly, total Parp1 protein levels were increased in WT mice in an age-dependent manner (from 3 to 18 months), but not in FXR-KO mice. Finally, activation of FXR in WT mice resulted in reduction of phosporylated Parp1 protein in the liver without affecting total Parp1 protein levels. In conclusion, this study reveals that FXR genetic status and agonist treatment affects basal levels and phosphorylation state of Parp1, respectively. These alterations, in turn, may be associated with the hepatobiliary alterations observed in FXR-KO mice and participate in FXR agonist-induced protection in the liver. -- Highlights: ? Proteomic analysis identified novel FXR targets. ? FXR modification altered post-translational modification of the Parp1 protein. ? Altered Parp1 function may contribute to mechanisms of FXR regulation of liver functions.

  2. MicroRNA-26a modulates transforming growth factor beta-1-induced proliferation in human fetal lung fibroblasts

    SciTech Connect (OSTI)

    Li, Xiaoou; Liu, Lian; Shen, Yongchun; Wang, Tao; Chen, Lei; Xu, Dan; Wen, Fuqiang

    2014-11-28

    Highlights: • Endogenous miR-26a inhibits TGF-beta 1 induced proliferation of lung fibroblasts. • miR-26a induces G1 arrest through directly targeting 3′-UTR of CCND2. • TGF indispensable receptor, TGF-beta R I, is regulated by miR-26a. • miR-26a acts through inhibiting TGF-beta 2 feedback loop to reduce TGF-beta 1. • Collagen type I and connective tissue growth factor are suppressed by miR-26a. - Abstract: MicroRNA-26a is a newly discovered microRNA that has a strong anti-tumorigenic capacity and is capable of suppressing cell proliferation and activating tumor-specific apoptosis. However, whether miR-26a can inhibit the over-growth of lung fibroblasts remains unclear. The relationship between miR-26a and lung fibrosis was explored in the current study. We first investigated the effect of miR-26a on the proliferative activity of human lung fibroblasts with or without TGF-beta1 treatment. We found that the inhibition of endogenous miR-26a promoted proliferation and restoration of mature miR-26a inhibited the proliferation of human lung fibroblasts. We also examined that miR-26a can block the G1/S phase transition via directly targeting 3′-UTR of CCND2, degrading mRNA and decreasing protein expression of Cyclin D2. Furthermore, we showed that miR-26a mediated a TGF-beta 2-TGF-beta 1 feedback loop and inhibited TGF-beta R I activation. In addition, the overexpression of miR-26a also significantly suppressed the TGF-beta 1-interacting-CTGF–collagen fibrotic pathway. In summary, our studies indicated an essential role of miR-26a in the anti-fibrotic mechanism in TGF-beta1-induced proliferation in human lung fibroblasts, by directly targeting Cyclin D2, regulating TGF-beta R I as well as TGF-beta 2, and suggested the therapeutic potential of miR-26a in ameliorating lung fibrosis.

  3. Development of Large High-Voltage PV Modules with Improved Reliability and Lower Cost: Final Subcontract Report, 1 April 2006--31 August 2007

    SciTech Connect (OSTI)

    Wohlgemuth, J.

    2009-05-01

    The overall objective was to provide NREL with technical results that enhance its capability to improve PV manufacturing technology by developing a PV module with specified characteristics.

  4. Supported PV module assembly

    DOE Patents [OSTI]

    Mascolo, Gianluigi; Taggart, David F.; Botkin, Jonathan D.; Edgett, Christopher S.

    2013-10-15

    A supported PV assembly may include a PV module comprising a PV panel and PV module supports including module supports having a support surface supporting the module, a module registration member engaging the PV module to properly position the PV module on the module support, and a mounting element. In some embodiments the PV module registration members engage only the external surfaces of the PV modules at the corners. In some embodiments the assembly includes a wind deflector with ballast secured to a least one of the PV module supports and the wind deflector. An array of the assemblies can be secured to one another at their corners to prevent horizontal separation of the adjacent corners while permitting the PV modules to flex relative to one another so to permit the array of PV modules to follow a contour of the support surface.

  5. Nonlinear interference noise in 100-Gbit s{sup -1} communication lines with the DP-QPSK modulation format

    SciTech Connect (OSTI)

    Gurkin, N V; Nanii, Oleg E; Novikov, A G; Plaksin, S O; Treshchikov, V N; Ubaydullaev, Rustam R

    2013-06-30

    The nonlinear interference noise power was measured experimentally as a function of the signal power and the length of the fibre coherent 100-Gbit s{sup -1} communication line, in which chromatic dispersion is not optically compensated. An expression was derived for the optimal signal power corresponding to a maximal excess of the measured optical signal-to-noise ratio (OSNR) over the OSNR required for conditionally error-free operation. The dependence of signal optimal power measured experimentally well agrees with the theoretical formula derived. (optical information transmission)

  6. Protecting Consumer Privacy while Building a Smarter Grid

    Broader source: Energy.gov [DOE]

    Smart grid technologies have the capacity to create tremendous new value for electricity consumers: from advanced IT and communication technologies that improve the overall operation of our nation’s electricity transmission and distribution networks; to smart meters and digital sensors that help utilities quickly identify and minimize the extent of outages when they do occur. In addition, consumers now have the ability to monitor and manage their electricity use in far greater detail by tapping into the data generated by smart meters. Many of these emerging technologies—which provide tremendous benefits not only for the nation’s electric system but for consumers throughout the United States—will result in an increase in the amount of data collected regarding grid operating characteristics, including customer energy use data. As the nation’s electric infrastructure is modernized, it is critically important to ensure that the collection of data is performed in a manner that yields the greatest benefits for consumers, while continuing to rigorously protect their privacy. Much progress has been made toward this goal to date. Earlier this month, the U.S. Department of Energy’s (DOE’s) Office of Electricity Delivery and Energy Reliability, in coordination with the Federal Smart Grid Task Force, finalized a 22-month multi-stakeholder effort to develop a Voluntary Code of Conduct (VCC) for utilities and third parties on protecting electricity consumers’ Customer Data which includes energy usage information.

  7. Modulation of DNA repair capacity and mRNA expression levels of XRCC1, hOGG1 and XPC genes in styrene-exposed workers

    SciTech Connect (OSTI)

    Hanova, Monika; Stetina, Rudolf; Vodickova, Ludmila; Vaclavikova, Radka; Hlavac, Pavel; Smerhovsky, Zdenek; Naccarati, Alessio; Polakova, Veronika; Soucek, Pavel; Kuricova, Miroslava; Manini, Paola; Kumar, Rajiv; Hemminki, Kari; Vodicka, Pavel

    2010-11-01

    Decreased levels of single-strand breaks in DNA (SSBs), reflecting DNA damage, have previously been observed with increased styrene exposure in contrast to a dose-dependent increase in the base-excision repair capacity. To clarify further the above aspects, we have investigated the associations between SSBs, micronuclei, DNA repair capacity and mRNA expression in XRCC1, hOGG1 and XPC genes on 71 styrene-exposed and 51 control individuals. Styrene concentrations at workplace and in blood characterized occupational exposure. The workers were divided into low (below 50 mg/m{sup 3}) and high (above 50 mg/m{sup 3}) styrene exposure groups. DNA damage and DNA repair capacity were analyzed in peripheral blood lymphocytes by Comet assay. The mRNA expression levels were determined by qPCR. A significant negative correlation was observed between SSBs and styrene concentration at workplace (R = - 0.38, p = 0.001); SSBs were also significantly higher in men (p = 0.001). The capacity to repair irradiation-induced DNA damage was the highest in the low exposure group (1.34 {+-} 1.00 SSB/10{sup 9} Da), followed by high exposure group (0.72 {+-} 0.81 SSB/10{sup 9} Da) and controls (0.65 {+-} 0.82 SSB/10{sup 9} Da). The mRNA expression levels of XRCC1, hOGG1 and XPC negatively correlated with styrene concentrations in blood and at workplace (p < 0.001) and positively with SSBs (p < 0.001). Micronuclei were not affected by styrene exposure, but were higher in older persons and in women (p < 0.001). In this study, we did not confirm previous findings on an increased DNA repair response to styrene-induced genotoxicity. However, negative correlations of SSBs and mRNA expression levels of XRCC1, hOGG1 and XPC with styrene exposure warrant further highly-targeted study.

  8. Ballasted photovoltaic module and module arrays

    DOE Patents [OSTI]

    Botkin, Jonathan; Graves, Simon; Danning, Matt

    2011-11-29

    A photovoltaic (PV) module assembly including a PV module and a ballast tray. The PV module includes a PV device and a frame. A PV laminate is assembled to the frame, and the frame includes an arm. The ballast tray is adapted for containing ballast and is removably associated with the PV module in a ballasting state where the tray is vertically under the PV laminate and vertically over the arm to impede overt displacement of the PV module. The PV module assembly can be installed to a flat commercial rooftop, with the PV module and the ballast tray both resting upon the rooftop. In some embodiments, the ballasting state includes corresponding surfaces of the arm and the tray being spaced from one another under normal (low or no wind) conditions, such that the frame is not continuously subjected to a weight of the tray.

  9. VERDE Analytic Modules

    Energy Science and Technology Software Center (OSTI)

    2008-01-15

    The Verde Analytic Modules permit the user to ingest openly available data feeds about phenomenology (storm tracks, wind, precipitation, earthquake, wildfires, and similar natural and manmade power grid disruptions and forecast power outages, restoration times, customers outaged, and key facilities that will lose power. Damage areas are predicted using historic damage criteria of the affected area. The modules use a cellular automata approach to estimating the distribution circuits assigned to geo-located substations. Population estimates servedmore » within the service areas are located within 1 km grid cells and converted to customer counts by conversion through demographic estimation of households and commercial firms within the population cells. Restoration times are estimated by agent-based simulation of restoration crews working according to utility published prioritization calibrated by historic performance.« less

  10. Modulation of mitochondrial function and morphology by interaction of Omi/HtrA2 with the mitochondrial fusion factor OPA1

    SciTech Connect (OSTI)

    Kieper, Nicole; Holmstroem, Kira M.; Ciceri, Dalila; Fiesel, Fabienne C.; Wolburg, Hartwig; Ziviani, Elena; Whitworth, Alexander J.; Martins, L. Miguel; Kahle, Philipp J.; Krueger, Rejko

    2010-04-15

    Loss of Omi/HtrA2 function leads to nerve cell loss in mouse models and has been linked to neurodegeneration in Parkinson's and Huntington's disease. Omi/HtrA2 is a serine protease released as a pro-apoptotic factor from the mitochondrial intermembrane space into the cytosol. Under physiological conditions, Omi/HtrA2 is thought to be involved in protection against cellular stress, but the cytological and molecular mechanisms are not clear. Omi/HtrA2 deficiency caused an accumulation of reactive oxygen species and reduced mitochondrial membrane potential. In Omi/HtrA2 knockout mouse embryonic fibroblasts, as well as in Omi/HtrA2 silenced human HeLa cells and Drosophila S2R+ cells, we found elongated mitochondria by live cell imaging. Electron microscopy confirmed the mitochondrial morphology alterations and showed abnormal cristae structure. Examining the levels of proteins involved in mitochondrial fusion, we found a selective up-regulation of more soluble OPA1 protein. Complementation of knockout cells with wild-type Omi/HtrA2 but not with the protease mutant [S306A]Omi/HtrA2 reversed the mitochondrial elongation phenotype and OPA1 alterations. Finally, co-immunoprecipitation showed direct interaction of Omi/HtrA2 with endogenous OPA1. Thus, we show for the first time a direct effect of loss of Omi/HtrA2 on mitochondrial morphology and demonstrate a novel role of this mitochondrial serine protease in the modulation of OPA1. Our results underscore a critical role of impaired mitochondrial dynamics in neurodegenerative disorders.

  11. Word Pro - Untitled1

    U.S. Energy Information Administration (EIA) Indexed Site

    7 Table 10.8 Photovoltaic Cell and Module Shipments by Type, Trade, and Prices, 1982-2010 Year U.S. Companies Reporting Shipments Shipments Trade Prices 1 Crystalline Silicon Thin-Film Total 2 Imports Exports Cells Modules Cells and Modules Modules Only Cells and Modules Modules Only Cells and Modules Modules Only Cells and Modules Modules Only Cells and Modules Modules Only Number Peak Kilowatts 3 Dollars 4 per Peak Watt 3 1982 19 NA NA NA NA 6,897 NA NA NA NA NA NA NA 1983 18 NA NA NA NA

  12. Module 4- Budgeting

    Broader source: Energy.gov [DOE]

    This module outlines basic costing concepts such as control accounts, work packages and planning packages.

  13. Modules Software Environment

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Environment » Modules Environment Modules Software Environment NERSC uses the module utility to manage nearly all software. There are two huge advantages of the module approach: NERSC can provide many different versions and/or installations of a single software package on a given machine, including a default version as well as several older and newer versions; and Users can easily switch to different versions or installations without having to explicitly specify different paths. With modules,

  14. Photovoltaic (PV) Module Level Remote Safety Disconnect - Energy Innovation

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    Portal Find More Like This Return to Search Photovoltaic (PV) Module Level Remote Safety Disconnect National Renewable Energy Laboratory Contact NREL About This Technology Figure 1: System configuration of emergency module-level disconnect using module-level &lsquo;Isolation Detection Units&rsquo; (IDU).<br /> Figure 1: System configuration of emergency module-level disconnect using module-level 'Isolation Detection Units' (IDU). Technology Marketing Summary The ability to

  15. Simultaneous Integrated Boost–Intensity Modulated Radiation Therapy With Concomitant Capecitabine and Mitomycin C for Locally Advanced Anal Carcinoma: A Phase 1 Study

    SciTech Connect (OSTI)

    Deenen, Maarten J.; Dewit, Luc; Boot, Henk; Beijnen, Jos H.; Faculty of Science, Department of Pharmaceutical Sciences, Division of Pharmaco-epidemiology and Clinical Pharmacology, Utrecht University, Utrecht ; Schellens, Jan H.M.; Faculty of Science, Department of Pharmaceutical Sciences, Division of Pharmaco-epidemiology and Clinical Pharmacology, Utrecht University, Utrecht ; Cats, Annemieke

    2013-04-01

    Purpose: Newer radiation techniques, and the application of continuous 5-FU exposure during radiation therapy using oral capecitabine may improve the treatment of anal cancer. This phase 1, dose-finding study assessed the feasibility and efficacy of simultaneous integrated boost–intensity modulated radiation therapy (SIB-IMRT) with concomitant capecitabine and mitomycin C in locally advanced anal cancer, including pharmacokinetic and pharmacogenetic analyses. Methods and Materials: Patients with locally advanced anal carcinoma were treated with SIB-IMRT in 33 daily fractions of 1.8 Gy to the primary tumor and macroscopically involved lymph nodes and 33 fractions of 1.5 Gy electively to the bilateral iliac and inguinal lymph node areas. Patients received a sequential radiation boost dose of 3 × 1.8 Gy on macroscopic residual tumor if this was still present in week 5 of treatment. Mitomycin C 10 mg/m{sup 2} (maximum 15 mg) was administered intravenously on day 1, and capecitabine was given orally in a dose-escalated fashion (500-825 mg/m{sup 2} b.i.d.) on irradiation days, until dose-limiting toxicity emerged in ≥2 of maximally 6 patients. An additional 8 patients were treated at the maximum tolerated dose (MTD). Results: A total of 18 patients were included. The MTD of capecitabine was determined to be 825 mg/m{sup 2} b.i.d. The predominant acute grade ≥3 toxicities included radiation dermatitis (50%), fatigue (22%), and pain (6%). Fifteen patients (83% [95%-CI: 66%-101%]) achieved a complete response, and 3 (17%) patients a partial response. With a median follow-up of 28 months, none of the complete responders, and 2 partial responders had relapsed. Conclusions: SIB-IMRT with concomitant single dose mitomycin C and capecitabine 825 mg/m{sup 2} b.i.d. on irradiation days resulted in an acceptable safety profile, and proved to be a tolerable and effective treatment regimen for locally advanced anal cancer.

  16. DOE HQ F 1511.1 | Department of Energy

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    511.1 DOE HQ F 1511.1 Form is used to identify individuals using the DOE Shuttle service. It is not retrievable by a personal identifier and is, therefore, not being kept in a Privacy Act system of records. Shuttle Bus Passenger List (5.89 KB) More Documents & Publications PIA - GovTrip (DOE data) General Privacy Act Guidance DOE F 206.1

  17. Photovoltaic manufacturing cost and throughput improvements for thin-film CIGS-based modules: Phase 1 technical report, July 1998--July 1999

    SciTech Connect (OSTI)

    Wiedeman, S.; Wendt, R.G.

    2000-03-01

    The primary objectives of the Global Solar Energy (GSE) Photovoltaic Manufacturing Technology (PVMaT) subcontract are directed toward reducing cost and expanding the production rate of thin-film CuInGaSe{sub 2} (CIGS)-based PV modules on flexible substrates. Improvements will be implemented in monolithic integration, CIGS deposition, contact deposition, and in-situ CIGS control and monitoring. In Phase 1, GSE has successfully attacked many of the highest risk aspects of each task. All-laser, selective scribing processes for CIGS have been developed, and many end-of-contract goals for scribing speed have been exceeded in the first year. High-speed ink-jet deposition of insulating material in the scribes now appears to be a viable technique, again exceeding some end-of-contract goals in the first year. Absorber deposition of CIGS was reduced corresponding to throughput speeds of up to 24-in/min, also exceeding an end-of-contract goal. Alternate back-contact materials have been identified that show potential as candidates for replacement of higher-cost molybdenum, and a novel, real-time monitoring technique (parallel-detector spectroscopic ellipsometry) has shown remarkable sensitivity to relevant properties of the CIGS absorber layer for use as a diagnostic tool. Currently, one of the bilayers has been baselined by GSE for flexible CIGS on polymeric substrates. Resultant back-contacts meet sheet-resistance goals and exhibit much less intrinsic stress than Mo. CIGS has been deposited, and resultant devices are comparable in performance to pure Mo back-contacts. Debris in the chamber has been substantially reduced, allowing longer roll-length between system cleaning.

  18. Wide-range voltage modulation

    SciTech Connect (OSTI)

    Rust, K.R.; Wilson, J.M.

    1992-06-01

    The Superconducting Super Collider`s Medium Energy Booster Abort (MEBA) kicker modulator will supply a current pulse to the abort magnets which deflect the proton beam from the MEB ring into a designated beam stop. The abort kicker will be used extensively during testing of the Low Energy Booster (LEB) and the MEB rings. When the Collider is in full operation, the MEBA kicker modulator will abort the MEB beam in the event of a malfunction during the filling process. The modulator must generate a 14-{mu}s wide pulse with a rise time of less than 1 {mu}s, including the delay and jitter times. It must also be able to deliver a current pulse to the magnet proportional to the beam energy at any time during ramp-up of the accelerator. Tracking the beam energy, which increases from 12 GeV at injection to 200 GeV at extraction, requires the modulator to operate over a wide range of voltages (4 kV to 80 kV). A vacuum spark gap and a thyratron have been chosen for test and evaluation as candidate switches for the abort modulator. Modulator design, switching time delay, jitter and pre-fire data are presented.

  19. 70005 MODULE AT-- U-X ASSY - Sh

    Broader source: All U.S. Department of Energy (DOE) Office Webpages (Extended Search)

    5 MODULE AT-- U-X ASSY MODULE U-X ASS'Y 1:10 1 6 RSF RSF RSF 70005 21607 - 21607 - - - INITIAL ISSUE - - WEIGHT: 3081 LBS FRONT (UPSTREAM SIDE) Parts List ITEM NO. QTY...

  20. Single Vocal Cord Irradiation: Image Guided Intensity Modulated Hypofractionated Radiation Therapy for T1a Glottic Cancer: Early Clinical Results

    SciTech Connect (OSTI)

    Al-Mamgani, Abrahim; Kwa, Stefan L.S.; Tans, Lisa; Moring, Michael; Fransen, Dennie; Mehilal, Robert; Verduijn, Gerda M.; Baatenburg de Jong, Rob J.; Heijmen, Ben J.M.; Levendag, Peter C.

    2015-10-01

    Purpose: To report, from a retrospective analysis of prospectively collected data, on the feasibility, outcome, toxicity, and voice-handicap index (VHI) of patients with T1a glottic cancer treated by a novel intensity modulated radiation therapy technique developed at our institution to treat only the involved vocal cord: single vocal cord irradiation (SVCI). Methods and Materials: Thirty patients with T1a glottic cancer were treated by means of SVCI. Dose prescription was set to 16 × 3.63 Gy (total dose 58.08 Gy). The clinical target volume was the entire vocal cord. Setup verification was done by means of an online correction protocol using cone beam computed tomography. Data for voice quality assessment were collected prospectively at baseline, end of treatment, and 4, 6, and 12 weeks and 6, 12, and 18 months after treatment using VHI questionnaires. Results: After a median follow-up of 30 months (range, 7-50 months), the 2-year local control and overall survival rates were 100% and 90% because no single local recurrence was reported and 3 patients died because of comorbidity. All patients have completed the intended treatment schedule; no treatment interruptions and no grade 3 acute toxicity were reported. Grade 2 acute dermatitis or dysphagia was reported in only 5 patients (17%). No serious late toxicity was reported; only 1 patient developed temporary grade 2 laryngeal edema, and responded to a short-course of corticosteroid. The VHI improved significantly, from 33.5 at baseline to 9.5 and 10 at 6 weeks and 18 months, respectively (P<.001). The control group, treated to the whole larynx, had comparable local control rates (92.2% vs 100%, P=.24) but more acute toxicity (66% vs 17%, P<.0001) and higher VHI scores (23.8 and 16.7 at 6 weeks and 18 months, respectively, P<.0001). Conclusion: Single vocal cord irradiation is feasible and resulted in maximal local control rate at 2 years. The deterioration in VHI scores was slight and temporary and

  1. Detailed Course Module Description

    Broader source: Energy.gov [DOE]

    This document lists the course modules for building science courses offered at Cornell's Collaborator Sustainable Buildingi Practice course.

  2. Module 8- Reporting

    Broader source: Energy.gov [DOE]

    This module illustrates and defines the different cost performance reports (CPR) available for reporting earned value information.

  3. Table 10.8 Photovoltaic Cell and Module Shipments by Type, Trade, and Prices, 1982-2010

    U.S. Energy Information Administration (EIA) Indexed Site

    Photovoltaic Cell and Module Shipments by Type, Trade, and Prices, 1982-2010 Year U.S. Companies Reporting Shipments Shipments Trade Prices 1 Crystalline Silicon Thin-Film Total 2 Imports Exports Cells Modules Cells and Modules Modules Only Cells and Modules Modules Only Cells and Modules Modules Only Cells and Modules Modules Only Cells and Modules Modules Only Number Peak Kilowatts 3 Dollars 4 per Peak Watt 3 1982 19 NA NA NA NA 6,897 NA NA NA NA NA NA NA 1983 18 NA NA NA NA 12,620 NA NA NA

  4. Integrating Module - NEMS Documentation

    Reports and Publications (EIA)

    2014-01-01

    Provides an overview of the complete National Energy Modeling System (NEMS) model, and includes brief descriptions of the modules with which the Integrating Module interacts. The emphasis and focus, however, is on the structure and function of the Integrating Module of NEMS.

  5. Modulating lignin in plants

    DOE Patents [OSTI]

    Apuya, Nestor; Bobzin, Steven Craig; Okamuro, Jack; Zhang, Ke

    2013-01-29

    Materials and methods for modulating (e.g., increasing or decreasing) lignin content in plants are disclosed. For example, nucleic acids encoding lignin-modulating polypeptides are disclosed as well as methods for using such nucleic acids to generate transgenic plants having a modulated lignin content.

  6. Compact nanomechanical plasmonic phase modulators

    SciTech Connect (OSTI)

    Dennis, B. S.; Haftel, M. I.; Czaplewski, D. A.; Lopez, D.; Blumberg, G.; Aksyuk, V. A.

    2015-03-30

    Highly confined optical energy in plasmonic devices is advancing miniaturization in photonics. However, for mode sizes approaching ≈10 nm, the energy increasingly shifts into the metal, raising losses and hindering active phase modulation. Here, we propose a nanoelectromechanical phase-modulation principle exploiting the extraordinarily strong dependence of the phase velocity of metal–insulator–metal gap plasmons on dynamically variable gap size. We experimentally demonstrate a 23-μm-long non-resonant modulator having a 1.5π rad range, with 1.7 dB excess loss at 780 nm. Analysis shows that by simultaneously decreasing the gap, length and width, an ultracompact-footprint π rad phase modulator can be realized. This is achieved without incurring the extra loss expected for plasmons confined in a decreasing gap, because the increasing phase-modulation strength from a narrowing gap offsets rising propagation losses. Such small, high-density electrically controllable components may find applications in optical switch fabrics and reconfigurable plasmonic optics.

  7. Thermoelectric power generator module of 16x16 Bi{sub 2}Te{sub 3} and 0.6%ErAs:(InGaAs){sub 1-x}(InAlAs){sub x} segmented elements

    SciTech Connect (OSTI)

    Zeng Gehong; Bahk, Je-Hyeong; Bowers, John E.; Lu Hong; Gossard, Arthur C.; Singer, Suzanne L.; Majumdar, Arun; Bian, Zhixi; Zebarjadi, Mona; Shakouri, Ali

    2009-08-24

    We report the fabrication and characterization of thermoelectric power generator modules of 16x16 segmented elements consisting of 0.8 mm thick Bi{sub 2}Te{sub 3} and 50 {mu}m thick ErAs:(InGaAs){sub 1-x}(InAlAs){sub x} with 0.6% ErAs by volume. An output power up to 6.3 W was measured when the heat source temperature was at 610 K. The thermoelectric properties of (InGaAs){sub 1-x}(InAlAs){sub x} were characterized from 300 up to 830 K. The finite element modeling shows that the performance of the generator modules can further be enhanced by improving the thermoelectric properties of the element materials, and reducing the electrical and thermal parasitic losses.

  8. PV Cell and Module Calibrations at NREL

    SciTech Connect (OSTI)

    Emery, Keith

    2012-10-22

    NREL has equipment to measure any conceivable cell or module technology. The lack of standards for low concentration modules complicates matters. Spectrally adjustable simulators are critical for more than three junctions. NREL's 10-channel fiber optic simulator has shown that the light can be set for each junction within 1% of what it would be under the reference spectrum for up to a five-junction cell. Uncertainty in module simulators dominated by spatial nonuniformity for calibration labs. Manufacturers can mitigate this error by using matched reference modules instead of cells.

  9. http://www1.eere.energy.gov/financing/solicitations_detail.html

    National Nuclear Security Administration (NNSA)

    Printable Version EERE Financial Opportunities Home | EERE Home | U.S. Department of Energy Webmaster | Web Site Policies | Security & Privacy | USA.gov Page 1 of 1 EERE Financial ...

  10. Thermoelectrics Partnership: Automotive Thermoelectric Modules...

    Office of Energy Efficiency and Renewable Energy (EERE) Indexed Site

    Solution for Automotive Thermoelectric Modules Application Thermoelectrics Partnership: Automotive Thermoelectric Modules with Scalable Thermo- and Electro-Mechanical Interfaces